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Sample records for carcinoma preliminary results

  1. Therapy of neuroendocrine carcinoma with Y-90 DOTA- preliminary results

    International Nuclear Information System (INIS)

    Full text: Aim: Cell membrane-specific somatostatin receptors are usually expressed by neuroendocrine tumors. Radiolabelled receptor-binding somatostatin analogues target tissues expressing these receptors and can be used for visualization and treatment. After the localization of tumors bearing somatostatin receptors with 111In or 99mTc labeled somatostatin analogues, in the case of high tumor uptake related to non target tissues, different radioisotopes have been used for their treatment. Thus, application of high doses of 111In- DTPA-octreotide had an impact on improvement of the clinical symptoms, without significant reduction of the tumor mass. However, 90Y somatostatin analogues (DOTA TOC, lanreotide) may be more effective for reduction of the tissue of the larger tumors while 177Lu labeled ones may be applied in smaller tumors. Combination of both of them seems to be the most effective therapy, particularly in tumors bearing both small and large lesions. The aim of this work is presentation of the preliminary results of the therapy of NETs with another octreotide analogue, 90Y DOTA TATE, which so far has been proved to have high therapeutic potential when labeled with 177Lu. Patients and methods: We investigated 7 patients with neuroendocrine tumors (two patients had neuroendocrine pancreatic carcinomas with liver metastases (one of them had metastases in peritoneal lymph nodes), one patient with operated (resected) bronchial carcinoid and liver metastases, three patients with neuroendocrine carcinomas of unknown origin and hepatic metastases (one with skeletal metastases) and one with pancreatic gastrinoma without metastases (surgery was impossible to perform). In all of them, together with other laboratory analyses and imaging methods, scintigraphy with somatostatin analogues was performed (in 3 with 111In Octreoscan and in the other 4 with 99mTc HYNIC TOC) and high tumor uptake was observed. The therapy was performed with 2- 4,5 GBq 90Y DOTA TATE per

  2. Preliminary results of 3-dimensional conformal radiotherapy for primary unresectable hepatocellular carcinoma

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    Keum, Ki Chang; Park, Hee Chul; Seong, Jin Sil; Chang, Sei Kyoung; Han, Kwang Hyub; Chon, Chae Yoon; Moon, Young Myoung; Kim, Gwi Eon; Suh, Chang Ok [Hallym University College of Medicine, Seoul (Korea, Republic of)

    2002-06-15

    The purpose of this study was to determine the potential role of three-dimensional conformal radiotherapy (3D-CRT) in the treatment of primary unresectable hepatocellular carcinoma. The preliminary results on the efficacy and the toxicity of 3D-CRT are reported. Seventeen patients were enrolled in this study, which was conducted prospectively from January 1995 to June 1997. The exclusion criteria included the presence of extrahepatic metastasis, liver cirrhosis of Child-Pugh classification C, tumors occupying more than two thirds of the entire liver, and a performance status of more than 3 on the ECOG scale. Two patients were treated with radiotherapy only while the remaining 15 were treated with combined transcatheter arterial chemoembolization. Radiotherapy was given to the field including the tumor plus a 1.5 cm margin using a 3D-CRT technique. The radiation dose ranged from 36 {approx} 60 Gy (median: 59.4 Gy). Tumor response was based on a radiological examination such as the CT scan, MR imaging, and hepatic artery angiography at 4 {approx} 8 weeks following the completion of treatment. The acute and subacute toxicities were monitored. An objective response was observed in 11 out of 17 patients, giving a response rate of 64.7%. The actuarial survival rate at 2 years was 21.2% from the start of radiotherapy (median survival; 19 months). Six patients developed a distant metastasis consisting of a lung metastasis in 5 patients and bone metastasis in one. The complications related to 3D-CRT were gastro-duodenitis ({>=} grade 2) in 2 patients. There were no treatment related deaths and radiation induced hepatitis. The preliminary results show that 3D-CRT is a reliable and effective treatment modality for primary unresectable hepatocellular carcinoma compared to other conventional modalities. Further studies to evaluate the definitive role of the 3D-CRT technique in the treatment of primary unresectable hepatocellular carcinoma are needed.

  3. Preliminary results of 3-dimensional conformal radiotherapy for primary unresectable hepatocellular carcinoma

    International Nuclear Information System (INIS)

    The purpose of this study was to determine the potential role of three-dimensional conformal radiotherapy (3D-CRT) in the treatment of primary unresectable hepatocellular carcinoma. The preliminary results on the efficacy and the toxicity of 3D-CRT are reported. Seventeen patients were enrolled in this study, which was conducted prospectively from January 1995 to June 1997. The exclusion criteria included the presence of extrahepatic metastasis, liver cirrhosis of Child-Pugh classification C, tumors occupying more than two thirds of the entire liver, and a performance status of more than 3 on the ECOG scale. Two patients were treated with radiotherapy only while the remaining 15 were treated with combined transcatheter arterial chemoembolization. Radiotherapy was given to the field including the tumor plus a 1.5 cm margin using a 3D-CRT technique. The radiation dose ranged from 36 ∼ 60 Gy (median: 59.4 Gy). Tumor response was based on a radiological examination such as the CT scan, MR imaging, and hepatic artery angiography at 4 ∼ 8 weeks following the completion of treatment. The acute and subacute toxicities were monitored. An objective response was observed in 11 out of 17 patients, giving a response rate of 64.7%. The actuarial survival rate at 2 years was 21.2% from the start of radiotherapy (median survival; 19 months). Six patients developed a distant metastasis consisting of a lung metastasis in 5 patients and bone metastasis in one. The complications related to 3D-CRT were gastro-duodenitis (≥ grade 2) in 2 patients. There were no treatment related deaths and radiation induced hepatitis. The preliminary results show that 3D-CRT is a reliable and effective treatment modality for primary unresectable hepatocellular carcinoma compared to other conventional modalities. Further studies to evaluate the definitive role of the 3D-CRT technique in the treatment of primary unresectable hepatocellular carcinoma are needed

  4. Very accelerated radiation therapy: preliminary results in locally unresectable head and neck carcinomas

    International Nuclear Information System (INIS)

    Purpose: To report preliminary results of a very accelerated radiation therapy Phase I/II trial in locally advanced head and squamous cell carcinomas (HNSCC). Methods and Materials: Between 01/92 and 06/93, 35 patients with an unresectable HNSCC were entered in this study. Thirty-two (91%) had Stage IV, and 3 had Stage III disease. The mean nodal diameter, in patients with clinically involved nodes (83%), was 6.3 cm. The median Karnovsky performance status was 70. The treatment consisted of a twice daily schedule (BID) giving 62 Gy in 20 days. Results: In all cases, confluent mucositis was observed, which started about day 15 and resolved within 6 to 10 weeks. Eighty percent of patients had enteral nutritional support. The nasogastric tube or gastrostomy was maintained in these patients for a mean duration of 51.8 days. Eighteen patients (53%) were hospitalized during the course of treatment due to a poor medical status or because they lived far from the center (mean 25 days). Nineteen patients (56%) (some of whom were initially in-patients) were hospitalized posttreatment for toxicity (mean 13 days). Five patients (15%) were never hospitalized. During the follow-up period, 12 local and/or regional failures were observed. The actuarial 18-month loco-regional control rate was 59% (95% confidence interval, 45-73%). Conclusions: The dramatic shortening of radiation therapy compared to conventional schedules in our series of very advanced HNSCC resulted in: (a) severe acute mucosal toxicity, which was manageable but required intensive nutritional support in all cases; and (b) high loco-regional response rates, strongly suggesting that the time factor is likely to be critical for tumor control in this type of cancer

  5. Preliminary results of phase I/II study of simultaneous modulated accelerated (SMART) for nasopharyngeal carcinoma

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    Park, Jin Hong; Lee, Sang Wook; Back, Geum Mun [College of Medicine, University of Ulsan, Asan Medical Center, Seoul (Korea, Republic of)] (and others)

    2006-03-15

    To present preliminary results of intensity-modulated radiotherapy (IMRT) using the simultaneous modulated accelerated radiation therapy (SMART) boost technique in patients with nasopharyngeal carcinoma (NPC). Twenty patients who underwent IMRT for non-metastatic NPC at the Asan Medical Center between September 2001 and December 2003 were prospectively evaluated. IMRT was delivered using the 'step and shoot' SMART technique at prescribed doses of 72 Gy (2.4 Gy/day) to the gross tumor volume (GTV), 60 Gy (2 Gy/day) to the clinical target volume (CTV) and metastatic nodal station, and 46 Gy (2 Gy/day) to the clinically negative neck region. Eighteen patients also received concurrent chemotherapy using cisplatin once per week. The median follow-up period was 27 months. Nineteen patients completed the treatment without interruption; the remaining patient interrupted treatment for 2 weeks owing to severe pharyngitis and malnutrition. Five patients (25%) had RTOG grade 3 mucositis, whereas nine (45%) had grade 3 pharyngitis. Seven patients (35%) lost more than 10% of their pretreatment weight, whereas 11 (55%) required intravenous fluids and/or tube feeding. There was no grade 3 or 4 chronic xerostomia. All patients showed complete response. Two patients had distant metastases and loco-regional recurrence, respectively. IMRT using the SMART boost technique allows parotid sparing, as shown clinically and by dosimetry, and may also be more effective biologically. A larger population of patients and a longer follow-up period are needed to evaluate ultimate tumor control and late toxicity.

  6. Preliminary results of chemoradiation as a primary treatment for vulvar carcinoma

    International Nuclear Information System (INIS)

    Purpose: To assess the role of chemoradiation as a primary treatment for vulvar carcinoma. Methods and Materials: Between December 1989 and August 1997, there were 14 patients with the diagnosis of squamous cell carcinoma of the vulva. Two patients were excluded from this study because of advanced stage at presentation. Key information about the remaining 12 patients was extracted from their charts. All patients had biopsy prior to treatment, and were treated with chemoradiation. Radiation was administered to the vulva only. Surgical biopsies from the vulva and inguinal nodal dissection were done 4-6 weeks after radiation treatment. All patients were followed for evaluation of response and clinical detection of recurrence. The period of follow-up ranged from 8 to 125 months. Mean follow-up period was 41 months. Results: All 12 patients showed complete response to the treatment. Only 1 patient (8.3%) developed local recurrence at 3 months posttreatment. Another patient (8.3%) developed nodal recurrence at 30 months posttreatment. Both patients were salvaged by surgical treatment and remained disease free. The actuarial 5-year disease-free survival was 43%. The actuarial 3-year disease-free survival was 84%. The majority of patients developed mild-to-moderate complications due to chemoradiation. These were well tolerated and responded to medical treatment. None of the patients developed late complications to chemoradiation treatment. Conclusions: Chemoradiation is an effective primary treatment for vulvar carcinoma as shown by these successfully managed cases

  7. 18F-fluorodeoxyglucose PET in ovarian carcinoma: methodology and preliminary results

    International Nuclear Information System (INIS)

    Aim of the present study was to evaluate 18FDG PET as a diagnostic tool in primary and recurrent ovarian cancer. Methods: PET of the abdomen and the pelvis was performed in 26 patients suspected for primary (n=17) or recurrent (n=9) ovarian cancer with an ECAT 953/15 scanner 45 min after intravenous administration of 245 MBq 18F-FDG (mean). PET findings were validated by surgery, histology and/or cytology. Results: Ovarian malignancies or recurrent ovarian cancer were demonstrated by PET in 16 out of 19 cases. Malignancy was excluded in six out of seven cases. False negative findings were obtained in two cases of low malignant potential tumors (LMP) and in one case of low grade serous/mucinous ovarian cystadenocarcinoma. PET yielded one false positive result in a case of salpingoophoritis. Quantitative analysis revealed a mean SUV of 6.8±2.3 in primary ovarian carcinoma vs. 2.6±1.2 in benign masses (p18FDG PET to be useful in diagnosis of recurrent ovarian cancer. PET is of limited use in differentiating LMP from benign tumors and ovarian cancer from inflammatory processes. Concerning this differentiation, quantitative analysis does not improve diagnostic accuracy. (orig.)

  8. Percutaneous microwave coagulation therapy combined with transcatheter arterial chmoembolization for hepatocellular carcinoma: preliminary results

    International Nuclear Information System (INIS)

    To evaluate the efficacy of percutaneous microwave coagulation therapy (PMCT) combined with transcatheter arterial chemoemboization (TACE) for the treatment of hepatocellular carcinoma (HCC). Twenty-five nodular HCCs (long diameter of 1.2-10 (mean, 3.4) cm) in 19 patients (15 males and 4 females) were treated by PMCT 4-138 days after TACE. Under ultrasound guidance, the carcinoma were punctured with a 14-G guideneedle through which a microwave electrode (25.0 cm in length, 1.6 mm in diameter) was inserted. To coagulate the HCCs and surrounding hepatic parenchyma, microwave irradiation at 60W for 45-60 seconds was then applied. One to three sessions of PMCT were performed at intervals of 2-6 days, and one week to 29 months later, the therapeutic effect was evaluated by spiral CT, angiography, and serum alpha-fetoprotein. Eighteen of 25 HCCs (72.0%) were necrotized completely, but seven (28.0%) recurred. Ninety percent of HCCs smaller than 4 cm in long diameter showed complete remission, but all those larger than 4 cm recurred. Alpha-fetoprotein levels decreased markedly in five patients (26.3 %), while in 12 (63.2%), asparate aminotransferase (AST)/alanine aminotransferase (ALT) showed transient elevation. Minor complications occurred after PMCT (mild abdominal pain in 8 patients, fever in 7, pleural effusion in 3, portal vein thrombosis in 1, and hepatic abscess in 1), but in no case was this serious. PMCT combined with TACE provides effective and safe treatment for nodular HCCs with a long diameter of less than 4 cm. (author)

  9. Preliminary results of transarterial Rhenium-188 HDD Lipiodol in treatment of inoperable primary hepatocellular carcinoma

    International Nuclear Information System (INIS)

    Full text: In this paper we present our early experience with a new radio-conjugate, namely rhenium-188 HDD Lipiodol (Re-188 lipiodol). Imported radiopharmaceuticals are generally expensive, particularly for developing countries. A Tungsten (W-188-Re 188) generator obtained from ORNL (Oak Ridge National Laboratory, Tennessee, USA) allows us on-site production of a beta emitting therapeutic isotope (Re-188) for up to 6 months from a single generator. The objectives of this study were to establish the safety of trans-arterial Re-188 lipiodol in patients with inoperable HCC, and determine the adverse effects and efficacy for this radio-conjugate treatment in a multi-center study of patients with advanced HCC. A multi-center study was sponsored by the International Atomic Energy Agency (Vienna) to assess the safety and efficacy of trans-arterial Re-188 HDD conjugated lipiodol (radio-conjugate) in the treatment of patients with inoperable hepatocellular carcinoma (HCC), The radio-conjugate was prepared by using a HDD (4-hexadecyl 1-2, 9, 9-tetramethyl-4, 7-diaza-1, 10-decanethiol) kit developed in Korea, and lipiodol. Over a period of eighteen months seventy patients received at least one treatment of radio-conjugate. Some patients were re-treated if there was no evidence of disease progression. The level of radio-conjugate administered was based on radiation-absorbed dose to critical normal organs, calculated following a 'scout' dose of radio-conjugate. The organs at greatest risk for radiation toxicity are the normal liver, the lung and the bone marrow. A specially designed spreadsheet was used to determine maximum tolerated activity (MTA), defined as the amount of radioactivity calculated to deliver no more than 12 Gray (Gy) to lungs, or 30 Gy to liver, or 1.5 Gy to bone marrow. These doses have been found to be safe in multiple trials using external beam therapy and systemically administered radiopharmaceuticals. Patients were followed for at least twelve weeks

  10. Preliminary results of transarterial rhenium-188 HDD lipiodol in the treatment of inoperable primary hepatocellular carcinoma

    International Nuclear Information System (INIS)

    of the study, when the activities administered started at 1.8 GBq (50 mCi) and rose to 7.7 GBq (206 mCi). In the efficacy phase of the study a further 54 patients were treated. Both groups of patients are included in this paper. The treatment activity of 188Re-lipiodol administered transarterially ranged from 1.8 to 9.8 GBq (50-265 mCi), with a mean activity of 4.6 GBq (124 mCi). Survival at 3 months was 90%, and at 6 months, 60%; 19% survived for 1 year. Mean survival after treatment in the total treated group of 70 patients was 9.5 months, with a range of 1-18 months. The results of the study show that 188Re-lipiodol is a safe and cost-effective method to treat primary HCC via the transarterial route. (orig.)

  11. Lobar Hepatocellular Carcinoma with Ipsilateral Portal Vein Tumor Thrombosis Treated with Yttrium-90 Glass Microsphere Radioembolization: Preliminary Results

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    M. Pracht

    2013-01-01

    Full Text Available Portal vein tumor thrombosis (PVTT is a common complication of hepatocellular carcinoma (HCC and has a negative impact on prognosis. This characteristic feature led to the rationale of the present trial designed to assess the efficacy and the safety of yttrium-90 glass-microsphere treatment for advanced-stage lobar HCC with ipsilateral PVTT. 18 patients with unresectable lobar HCC and ipsilateral PVTT were treated in our institution with 90Y-microS radioembolization. Patients were evaluated every 3 to 6 months for response, survival, and toxicity. Mean follow-up was 13.0 months (2.2–50.6. Outcomes were: complete response (n=2, partial response (n=13, stable disease (n=1, and progressive disease (n=2 giving a disease control rate of 88.9%. Four patients were downstaged. Treating lobar hepatocellular carcinoma with ipsilateral portal vein thrombosis with yttrium-90 glass-microsphere radioembolization is safe and efficacious. Further clinical trials are warranted to confirm these results and to compare 90Y-microS with sorafenib, taking into account not only survival but also the possibility of secondary surgery for putative curative intention after downstaging.

  12. Predicting tumor sizes of ductal carcinoma in situ from immunohistochemical images using a novel approach of mathematical pathology: preliminary results, potentials and challenges ahead

    Science.gov (United States)

    Chuang, Yao-Li; Edgerton, Mary; Macklin, Paul; Yang, Wei; Bearer, Elaine; Cristini, Vittorio

    2012-02-01

    Differential equation models have recently drawn increasing attentions as a useful tool to help advance the knowledge in cancer research. However, challenges remain for applying such models to clinical practices on a patient-specific basis to assist surgical decisions. Clinical diagnoses essentially at a single time point are often insufficient to fully constrain the time-dependent differential equations. Here we present a novel mathematical pathology approach, identifying robust indicators for time-invariant predictions of the model that can be used for surgical planning. We demonstrate this approach by predicting the sizes of ductal carcinoma in situ by calibrating model parameters from immunohistochemical images. Our preliminary studies of 17 excised tumor cases resulted in a better agreement with the actual measured sizes than the other estimates available to us, showing the potential of our approach for patient-specific cancer diagnosis. Conversely, our studies also revealed challenges to overcome before we can take this approach to the next level.

  13. Evaluation of image quality and dose in thoracic spiral CT examination in patients with pulmonary carcinoma. Preliminary results

    International Nuclear Information System (INIS)

    We have applied criteria for CT quality defined in the European Guidelines to a samples of thoracic CT examinations for the indication of pulmonary carcinoma of 5 institutions of the Community of Madrid that have spiral CT equipment. The selected examinations have been evaluated independently by five radiologists to determine the degree of adherence to the quality criteria for image defined in the Guidelines s for examinations of general thorax. Dosimetric measurements carried out in parallel have served to estimate the values of CT (CTDIw) dose indices, dose-length product (DLP) and effective dose for every patient. The result show a high global adherence to the quality criteria (96%), with averages per institution being between 94% (in two institutions) and 98% (in three institutions). There are 10 of 16 criteria that are adhered to in all examinations of the sample: those which are not adhered to systematically are: two of visualization (1.1 and 1.4), with 92-96% fulfillment, and four of critical reproduction (2.6; 2.8; 2.9 and 2.10), with percentages of adherence between 91% and 96%. The average CTDIw values per institution are in the interval 12.9-19.1 mGy; those of DLP between 263 and 577 mGy cm and those of effective dose between 4.2 and 9.2 mSv. The DLP-image quality correlation in institutions with the best image quality was null in two of them and direct and moderate in the third. In both institutions with the poorest image: (Author) 20 refs

  14. Preliminary results of magnetic resonance imaging-aided high-dose-rate interstitial brachytherapy for recurrent uterine carcinoma after curative surgery

    International Nuclear Information System (INIS)

    This report presents initial experience with imaging-aided high-dose-rate interstitial brachytherapy (HDR-ISBT) for post-operative recurrence of uterine carcinoma. Fourteen patients presenting with post-operative recurrence of uterine carcinoma (nine cervix and five corpus) between July 2005 and October 2008 were enrolled in this study (median follow-up: 37 months, range: 6-59 months). We implanted magnetic resonance imaging (MRI)-compatible plastic applicators using our own ambulatory technique. HDR-ISBT treatment consisted of twice-a-day irradiation of 6 Gy each with at least a six-hour interval to provide the total prescribed dose. Treatment was based on treatment planning-computed tomography with MRI as a reference. Seven patients were treated with a combination of ISBT (median 30 Gy/5 fractions; range: 27-33 Gy) and external beam radiation therapy (EBRT), and the other seven with brachytherapy only (median 54 Gy/9 fractions; range: 48-54 Gy), one of whom had previously received pelvic EBRT. The three-year estimates of local control and overall survival rates were 77.9% (95% confidence interval (CI): 55.8-100%) and 77.1% (95% CI: 54.2-100%), respectively. Two patients, who had received combined treatment with EBRT showed untoward reactions, including a grade 3 subileus and grade 2 constipation. Another patient, who had been treated with ISBT alone, developed grade 2 urinary constriction. Our imaging-aided HDR-ISBT for post-operative recurrence of uterine carcinoma was found to be practical with promising preliminary results. (author)

  15. Dynamic contrast-enhanced computed tomography as a potential biomarker in patients with metastatic renal cell carcinoma: preliminary results from the Danish Renal Cancer Group Study-1

    DEFF Research Database (Denmark)

    Mains, Jill Rachel; Donskov, Frede; Pedersen, Erik Morre;

    2014-01-01

    OBJECTIVES: The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS: Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group...... and clear cell mRCC participating in an ongoing prospective randomized phase II trial comprising interleukin-2-based immunotherapy and bevacizumab were included in this preliminary analysis. All patients had a follow-up time of at least 2 years. Interpretation of DCE-CT (max slope method) was...

  16. Positron emission tomography with [18F]FDOPA and [18F]FDG in the imaging of small cell lung carcinoma: preliminary results

    International Nuclear Information System (INIS)

    Small cell lung carcinomas (SCLC) express neuroendocrine markers, and dihydroxyphenylalanine (DOPA) is known to accumulate in neuroendocrine tumours. This study was performed with the aim of evaluating the uptake of 3,4-dihydroxy-6-18F-fluoro-phenylalanine ([18F]FDOPA) by SCLC, based on comparison with the results of fluorine-18 fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) and standard imaging procedures. [18F]FDG PET and [18F]FDOPA PET were performed on four patients with newly diagnosed SCLC. There was agreement between the results of [18F]FDOPA PET and [18F]FDG PET in four tumoural sites out of 11, whereas [18F]FDG PET and standard imaging procedures were in full agreement. A semi-quantitative analysis based on standardised uptake values (SUVs) was performed in order to compare [18F]FDG and [18F]FDOPA tumour uptake. The median [18F]FDG SUVmax was 5.9 (with a 95% confidence interval from 4.4 to 9.2), while the median [18F]FDOPA SUVmax was 1.9 (with a 95% confidence interval from 1.6 to 3.8). The difference between [18F]FDG SUVmax and [18F]FDOPA SUVmax was significant (P18F]FDOPA PET appeared less sensitive than [18F]FDG PET and standard imaging procedures in the staging of SCLC. No clear relation between [18F]FDOPA uptake and positivity of neuroendocrine markers on immunohistochemistry emerged from these preliminary results; however, since [18F]FDOPA uptake may reflect better differentiation of the tumour, and possibly a better prognosis, this point warrants clarification in a larger study. (orig.)

  17. Clinical effect of meso-tetrahydroxyphenylchlorine based photodynamic therapy in recurrent carcinoma of the ovary: preliminary results.

    Science.gov (United States)

    Wierrani, F; Fiedler, D; Grin, W; Henry, M; Dienes, E; Gharehbaghi, K; Krammer, B; Grünberger, W

    1997-03-01

    This article addresses the use of meso-tetrahydroxyphenylchlorin-based photodynamic therapy (m-THPC-PDT) to treat recurrent gynaecologic malignancies of the ovary. Photodynamic therapy is an experimental approach in the treatment of neoplasms and results indicate it is a highly tissue selective, relatively simple intervention with few side effects, therefore reducing the overall burden on the patient. Of the three patients involved in the initial study, two were treated solely with photodynamic therapy by laparoscopy, and one underwent additional palliative debulking surgery of metastatic tumours. After a post-operative period of more than two years all three women remained free of relapses. PMID:9091020

  18. [Preliminary results of treatment of hormone-dependent metastatic carcinoma of the breast with the bromocriptin-medroxyprogesterone acetate combination].

    Science.gov (United States)

    Mussa, A; Dogliotti, L; Di Carlo, F

    1977-06-30

    A brief account of the concept of hormone dependence in breast neoplasia is followed by the presentation of results obtained with an association of medroxyprogesterone acetate (MAP) and 2-bromo-alpha-ergocriptine (CB 154) in 14 women with metastatic cancer of the breast, hormone dependent due to the presence of the cytoplasmic receptor for 17-beta-oestradiol. All patients, in fertile or premenopausal stage, were subjected to prior surgical ovariectomy. MAP was given i.m. at a dose of 1 g/day for 30 days and then 150 mg/day. In the same time 2.5 mg CB 154 were administered every 6 hr per os. Evaluation in accordance with the criteria proposed by the Coop Breast Cancer Group showed that rapid improvement was obtained in all cases, persisting (at the time of writing) for a minimum of 6 months to a maximum of 2 yr of observation. In addition, rapid disappearance of pain was noted, particularly in subjects with secondary bone lesions. Side-effects were in all cases of slight consequence and suspension of the treatment was never necessary. The mechanism of the two drugs and the advantages of their association are discussed. PMID:577604

  19. Combined proton and photon conformal radiation therapy for locally advanced carcinoma of the prostate: preliminary results of a phase I/II study

    International Nuclear Information System (INIS)

    Purpose: A study was developed to evaluate the use of combined photons and protons for the treatment of locally advanced carcinoma of the prostate. This report is a preliminary assessment of treatment-related morbidity and tumor response. Methods and Materials: One hundred and six patients in stages T2b (B2), T2c (B2), and T3 (C) were treated with 45 Gy photon-beam irradiation to the pelvis and an additional 30 Cobalt Gray Equivalent (CGE) to the prostate with 250-MeV protons, yielding a total prostate dose of 75 CGE in 40 fractions. Median follow-up time was 20.2 months (range: 10-30 months). Toxicity was scored according to the Radiation Therapy Oncology Group (RTOG) grading system; local control was evaluated by serial digital rectal examination (DRE) and prostate specific antigen (PSA) measurements. Results: Morbidity evaluation was available on 104 patients. The actuarial 2-year rate of Grade 1 or 2 late morbidity was 12% (8% rectal, 4% urinary). No patients demonstrated Grade 3 or 4 late mobidity. Treatment response was evaluated on 100 patients with elevated pretreatment serum PSA levels. The actuarial 2-year rate of PSA normalization was 96%, 97%, and 63% for pretreatment PSAS of > 4-10, > 10-20, and > 20, respectively. The 13 patients with rising PSA demonstrated local recurrence (3 patients), distant metastasis (8 patients), or no evidence of disease except increasing PSA (2 patients). Conclusion: The low incidence of side effects, despite the tumor dose of 75 CGE, demonstrates that conformal protons can deliver higher doses of radiation to target tissues without increasing complications to surrounding normal tissues. The initial tumor response, as assessed by the high actuarial rate of normalization with pretreatment PSA ≤ 20, and the low rate of recurrences within the treatment field (2.8%), are encouraging

  20. {sup 18}F-fluorodeoxyglucose PET in ovarian carcinoma: methodology and preliminary results; {sup 18}F-Fluordeoxyglukose PET beim Ovarialkarzinom: Methodik und erste Ergebnisse

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    Zimny, M.; Cremerius, U.; Buell, U. [Technische Hochschule Aachen (Germany). Klinik fuer Nuklearmedizin; Schroeder, W.; Wolters, S.; Rath, W. [Technische Hochschule Aachen (Germany). Frauenklinik

    1997-10-01

    Aim of the present study was to evaluate {sup 18}FDG PET as a diagnostic tool in primary and recurrent ovarian cancer. Methods: PET of the abdomen and the pelvis was performed in 26 patients suspected for primary (n=17) or recurrent (n=9) ovarian cancer with an ECAT 953/15 scanner 45 min after intravenous administration of 245 MBq {sup 18}F-FDG (mean). PET findings were validated by surgery, histology and/or cytology. Results: Ovarian malignancies or recurrent ovarian cancer were demonstrated by PET in 16 out of 19 cases. Malignancy was excluded in six out of seven cases. False negative findings were obtained in two cases of low malignant potential tumors (LMP) and in one case of low grade serous/mucinous ovarian cystadenocarcinoma. PET yielded one false positive result in a case of salpingoophoritis. Quantitative analysis revealed a mean SUV of 6.8{+-}2.3 in primary ovarian carcinoma vs. 2.6{+-}1.2 in benign masses (p<0.05). Conclusion: These preliminary data show {sup 18}FDG PET to be useful in diagnosis of recurrent ovarian cancer. PET is of limited use in differentiating LMP from benign tumors and ovarian cancer from inflammatory processes. Concerning this differentiation, quantitative analysis does not improve diagnostic accuracy. (orig.) [Deutsch] Ziel der vorliegenden Studie war die Evaluierung der PET mit {sup 18}F-Fluordeoxyglukose in der Primaer- und Rezidivdiagnostik von Ovarialkarzinomen. Methoden: Untersucht wurden 26 Patientinnen mit Verdacht auf primaeres Ovarialkarzinom (n=17) bzw. Rezidivverdacht (n=9). Die PET-Untersuchung von Abdomen und Becken erfolgte mit einem ECAT 953/15-Scanner beginnend 45 min nach i.v. Applikation von im Mittel 245 MBq {sup 18}FDG. Die PET-Ergebnisse wurden anhand von intraoperativem Befund, Histologie und Zytologie validiert. Ergebnisse: Der richtige Nachweis eines primaeren, malignen Ovarialtumors bzw. eines Rezidivs gelang in 16 von 19 Faellen, der Malignomausschluss in sechs von sieben Faellen. Falsch negative PET

  1. Evaluation of patients with metastatic bone lesions from breast carcinoma using whole body scintigraphy with pentavalent technetium-99m dimercaptosuccinic acid: preliminary results

    International Nuclear Information System (INIS)

    Pentavalent technetium-99m dimercaptosuccinic acid (DMSA(V)-99mTc) was designed as a tumor-seeking agent, chemically different from its analog trivalent used in renal tubular studies. This radiopharmaceutical was introduced in 1984 and has been used in oncologic application. It was proposed as a new agent for detecting metastases from breast carcinoma in 1992. Aim: To evaluate the sensibility and specificity of the scintigraphic study with DMSA(V)-99mTc in bone metastatic disease from breast carcinoma. Materials and Methods: Prospective study was done in 10 female patients, with average age of 49.8 years (42 to 73) with breast carcinoma and metastatic bone disease. All patients were submitted to whole body scanning with methylene diphosphonate-99mTc (MDP-99mTc) and DMSA(V)-99mTc. The sensibility and the specificity were calculated. Results: A total of one hundred eighty-nine bone lesions were diagnosed clinically and by follow-up, radiographic exams, scintigraphy or biopsy. The presence of 178 metastatic lesions and 11 benign lesions was detected. DMSA(V)-99mTc concentrated in 165 lesions that matched with the MDP-99mTc concentration. Only one benign lesion concentrated the DMSA(V)-99mTc and was established as a false-positive by biopsy. No concentration of DMSA(V)-99mTc was found in other 10 benign lesions that had increased uptake of MDP-99mTc. High accumulation of DMSA(V)-99mTc was observed in liver metastases on one patient with no corresponding concentration of MDP-99mTc. In this study, the use of DMSA(V)-99mTc to detect bone metastases showed 92.1% of sensibility and 90.9% of specificity. Conclusion: High sensibility and specificity to metastatic bone disease from breast carcinoma were found on scintigraphic study with DMSA(V)-99mTc. It suggests that it could be used as an adjuvant technique in scintigraphic bone evaluation in patients with breast carcinoma, improving the specificity of MDP-99mTc bone scans

  2. Concurrent Chemoradiotherapy With Paclitaxel and Nedaplatin Followed by Consolidation Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Uterine Cervix: Preliminary Results of a Phase II Study

    International Nuclear Information System (INIS)

    Purpose: To evaluate the efficacy and toxicities of concurrent chemoradiotherapy (CCRT) and consolidation chemotherapy in patients with locally advanced squamous cell cervical carcinoma. Methods and Materials: Patients with LASCC (FIGO Stage IIB-IIIB) were treated with pelvic external beam radiotherapy (45 Gy for Stage IIB and 50 Gy for Stage III) and high-dose-rate intracavitary brachytherapy (50 Gy for Stage IIB and 35 Gy for Stage III). The cumulative dose at point A was 50 Gy for Stage IIB and 65 Gy for Stage III. Concurrent chemotherapy with paclitaxel (35 mg/m2) and nedaplatin (20 mg/m2) was given every week for 6 weeks. Consolidation chemotherapy with paclitaxel (135 mg/m2) and nedaplatin (60 mg/m2) was administered every 3 weeks for 4 cycles. Results: All patients completed CCRT, and 28 of 34 patients completed consolidation chemotherapy. The complete response rate was 88% (95% CI, 73-96%). The most common Grade 3 or higher toxicities were leukopenia/neutropenia (10.9% of the cycles). During a median follow up of 23 months (range, 14-30 months), 5 patients had locoregional failure and 1 patient had distant metastasis. The estimated 2-year progression-free survival and overall survival were 82% (95% CI, 68-95%) and 93% (95% CI, 83-100%), respectively. Grade 3 late complications occurred in 3 patients (9%). Conclusions: CCRT with paclitaxel and nedaplatin followed by consolidation chemotherapy is well tolerated and effective in patients with locally advanced squamous cell cervical carcinoma. Further randomized trials of comparing this regimen with the standard treatment are worth while.

  3. Development and application of dynamic MR-imaging for evaluation of perfusion changes in rectal carcinoma during a course of radiotherapy in clinical use. Preliminary results

    International Nuclear Information System (INIS)

    Purpose: This study was aimed at measuring microcirculatory parameters and contrast medium accumulation within the rectal carcinoma during fractionated radiotherapy in the clinical setting. Material and methods: Perfusion data were observed in patients with rectal carcinoma (n=8) who underwent a preoperative combined chemo-radiotherapy. To acquire perfusion data, an ultrafast T1 mapping sequence was carried out on a 1.5-Tesla whole body imager to obtain T1 maps at intervals of 14 or 120 seconds. The overall measurement time was 40 minutes. The transaxial slice thickness (5 mm) was chosen in such a way that both arterial vessels and the tumor could be clearly identified. The gadolinium-DTPA (Gd-DTPA) concentration time curve was evaluated for arterial blood and tumor after intravenous constant rate infusion. The method allows a spatial resolution of 2x2x5 mm and a temporal resolution of 14 seconds. Patients underwent MR imaging before and at constant intervals during fractionated radiotherapy. Results: Spatial and temporal resolution of dynamic T1 mapping was sufficient to reveal varying CM accumulation levels within the tumor and to identify the great arteries in the pelvis. In 6 patients Gd-DTPA concentration-time-curves were evaluated within the tumor during radiation. Pi index of Gd-DTPA versus radiation dose showed a significant increase in the first or second week of treatment, then either returned slowly to retreatment level or a renewed increase was observed. The average Pi-value at the beginning was 0.16 (±0.049), reaching highest level of 0.23 (±0.058). In all groups the rise from the Pi-value to the Pi-maximum was statistically significant. The relative increase in perfusion ranged between 20 to 83%. Conclusion: The results show, that the ultrafast MR-technique described above provide a suitable tool for monitoring tumor microcirculation during therapeutic interventions and offers the potential for an individualized optimization of therapeutic

  4. Thyroid medullary carcinoma and PET/CT with {sup 18}F-DOPA in the post surgery follow up: preliminary results; Carcinome medullaire de la thyroide et TEP/TDM a la {sup 18}F-DOPA dans le suivi post-chirurgical: resultats preliminaires

    Energy Technology Data Exchange (ETDEWEB)

    Keomany, J.; Rust, E.; Constantinesco, A.; Imperiale, A. [CHU de Strasbourg, Service de biophysique et medecine nucleaire, 67 (France); Detour, J. [CHU de Strasbourg, Service de radiopharmacie, 67 (France); Chabrier, G.; Goichot, B. [CHU de Strasbourg, Service de medecine interne, endocrinologie et nutrition, 67 (France); Schneegans, O. [FNCLCC Paul-Strauss, 67 - Strasbourg (France)

    2010-07-01

    Purpose: to study the contribution of the PET/CT with {sup 18}F DOPA in the therapy follow-up of patients with a history of medullary thyroid carcinoma and biological suspicion of residual disease or recurrence. Conclusions: The preliminary results show the interest of the PET/CT with {sup 18}F DOPA in the therapy follow-up and the management of patients suffering of medullary thyroid carcinoma in biological relapse. (N.C.)

  5. Advanced Hepatocellular Carcinoma: Early evaluation of response to targeted therapy and prognostic value of Perfusion CT and Dynamic Contrast Enhanced-Ultrasound. Preliminary results

    International Nuclear Information System (INIS)

    Purpose: To investigate whether there is any correlation between standard endpoints and tumor perfusion measurements with Perfusion CT and Dynamic Contrast-Enhanced Ultrasonography (DCE-US) in patients with advanced Hepatocellular Carcinoma (HCC) treated with targeted therapy. Materials and methods: Nineteen patients were evaluated during targeted therapy (sorafenib n = 16, sunitinib n = 3). Changes in tumor perfusion measurements between baseline and month 1 were assessed and compared using RECIST progression criteria at month 2. Results: Median time to progression according to RECIST was 117 days and median time to death was 208 days. Perfusion CT values before treatment were significantly increased in HCC compared to the surrounding liver (n = 17, P < .02). Eleven patients received complete examinations with both techniques at baseline and month 1. A non-significant decrease was found in all Perfusion CT values between RECIST nonprogressors (n = 7) and progressors (n = 4): mean Blood Volume: −27.9 vs. −11.1% and mean Blood Flow: −25.0 vs. −11.7% respectively. With DCE-US, opposite changes were found (mean Area Under the Curve AUC: −38.3 vs. 436.3%). RECIST progression at month 2 was significantly correlated with a threshold 40% decrease in AUC (P = .015). None of the patients with a decrease in AUC ≥ 40% was a progressor at month 2. Conclusion: Despite perfusion changes with both Perfusion CT and DCE-US in patients receiving treatment, only DCE-US at month 1 (with a decrease in the AUC of more than 40%) predicted non-progression at month 2 and may be a potential surrogate marker of tumor response during targeted therapy

  6. Advanced Hepatocellular Carcinoma: Early evaluation of response to targeted therapy and prognostic value of Perfusion CT and Dynamic Contrast Enhanced-Ultrasound. Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Frampas, Eric, E-mail: eric.frampas@chu-nantes.fr [Central Department of Radiology and Medical Imaging, Hôtel-Dieu, 1 Place Alexis Ricordeau, 44093 Nantes Cedex 1 (France); Lassau, Nathalie, E-mail: Nathalie.LASSAU@igr.fr [IR4M UMR 8081, Université Paris Sud 11, Institut Gustave Roussy, 114 Av. Edouard Vaillant, 94805 Villejuif (France); Zappa, Magaly, E-mail: magaly.zappa@bjn.aphp.fr [Department of Radiology, APHP Assistance Publique-Hôpitaux de Paris, Hôpital Beaujon, 100 Bd du général Leclerc, 92110 Clichy (France); Vullierme, Marie-Pierre, E-mail: marie-pierre.vullierme@bjn.aphp.fr [Department of Radiology, APHP Assistance Publique-Hôpitaux de Paris, Hôpital Beaujon, 100 Bd du général Leclerc, 92110 Clichy (France); Koscielny, Serge, E-mail: serge.koscielny@igr.fr [Department of Biostatistics, Institut Gustave Roussy, 114 Av. Edouard Vaillant, 94805 Villejuif (France); Vilgrain, Valérie, E-mail: valerie.vilgrain@bjn.aphp.fr [Department of Radiology, APHP Assistance Publique-Hôpitaux de Paris, Hôpital Beaujon, 100 Bd du général Leclerc, 92110 Clichy (France); Université Paris Diderot, Sorbonne Paris Cité, INSERM CRB3 U773, 75018 Paris (France)

    2013-05-15

    Purpose: To investigate whether there is any correlation between standard endpoints and tumor perfusion measurements with Perfusion CT and Dynamic Contrast-Enhanced Ultrasonography (DCE-US) in patients with advanced Hepatocellular Carcinoma (HCC) treated with targeted therapy. Materials and methods: Nineteen patients were evaluated during targeted therapy (sorafenib n = 16, sunitinib n = 3). Changes in tumor perfusion measurements between baseline and month 1 were assessed and compared using RECIST progression criteria at month 2. Results: Median time to progression according to RECIST was 117 days and median time to death was 208 days. Perfusion CT values before treatment were significantly increased in HCC compared to the surrounding liver (n = 17, P < .02). Eleven patients received complete examinations with both techniques at baseline and month 1. A non-significant decrease was found in all Perfusion CT values between RECIST nonprogressors (n = 7) and progressors (n = 4): mean Blood Volume: −27.9 vs. −11.1% and mean Blood Flow: −25.0 vs. −11.7% respectively. With DCE-US, opposite changes were found (mean Area Under the Curve AUC: −38.3 vs. 436.3%). RECIST progression at month 2 was significantly correlated with a threshold 40% decrease in AUC (P = .015). None of the patients with a decrease in AUC ≥ 40% was a progressor at month 2. Conclusion: Despite perfusion changes with both Perfusion CT and DCE-US in patients receiving treatment, only DCE-US at month 1 (with a decrease in the AUC of more than 40%) predicted non-progression at month 2 and may be a potential surrogate marker of tumor response during targeted therapy.

  7. Preliminary Results of a Prospective Randomized Trial Comparing Concurrent Chemoradiotherapy Plus Adjuvant Chemotherapy With Radiotherapy Alone in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma in Endemic Regions of China

    International Nuclear Information System (INIS)

    Purpose: A prospective randomized trial was performed to evaluate the efficacy of concurrent chemotherapy and adjuvant chemotherapy in patients with locoregionally advanced nasopharyngeal carcinoma (NPC) in endemic regions of China. Methods and Materials: Between July 2002 and September 2005, 316 eligible patients were randomly assigned to receive either radiotherapy alone (RT) or chemoradiotherapy concurrent with adjuvant chemotherapy (CRT). All patients received 70 Gy in 7 weeks using standard RT portals and techniques. The CRT patients were given concurrent cisplatin (40 mg/m2 on Day 1) weekly during RT, followed by cisplatin (80 mg/m2 on Day 1) and fluorouracil (800 mg/m2 on Days 1-5) every 4 weeks (Weeks 5, 9, and 13) for three cycles after completion of RT. All patients were analyzed by intent-to-treat analysis. Results: The two groups were well-balanced in all prognostic factors and RT parameters. The CRT group experienced significantly more acute toxicity (62.6% vs. 32%, p = 0.000). A total of 107 patients (68%) and 97 patients (61%) completed all cycles of concurrent chemotherapy and adjuvant chemotherapy, with a median follow-up time of 29 months. The 2-year overall survival rate, failure-free survival rate, distant failure-free survival rate, and locoregional failure-free survival rate for the CRT and RT groups were 89.8% vs. 79.7% (p = 0.003), 84.6% vs. 72.5% (p = 0.001), 86.5% vs. 78.7% (p = 0.024), and 98.0% vs. 91.9% (p = 0.007), respectively. Conclusions: This trial demonstrated the significant survival benefits of concurrent chemotherapy plus adjuvant chemotherapy in patients with locoregionally advanced NPC in endemic regions of China

  8. MR analysis of nasopharyngeal carcinoma: correlation of the pattern of tumor extent at the primary site with the distribution of metastasized cervical lymph nodes. Preliminary results

    International Nuclear Information System (INIS)

    The purpose of this study was to correlate the pattern of tumor extent of nasopharyngeal carcinoma at the primary site on magnetic resonance (MR) imaging with the distribution of cervical lymph node metastasis. MR images of 32 patients with biopsy-proven nasopharyngeal carcinoma were reviewed and classified into five patterns of tumor extent in correlation with the distribution of cervical lymphadenopathy. The assessment of cervical lymph node metastasis was done on the basis of the computed tomography (CT) findings. The tumor volume was also correlated with the occurrence of contralateral lymphadenopathy. Of the 32 patients, five (16 %) presented as type 1, tumor limited to the nasopharyngeal mucosa; 12 (38 %) as type 2 a, tumor which had invaded either lateral side but did not extend over the roof of nasopharynx; three (9 %) as type 2 b, tumor which had invaded bilaterally across the midline but did not extend over the roof of nasopharynx; three (9 %) as type 2 c, tumor which had invaded mainly the skull base but did not cross the midline; and nine (28 %) as type 3, tumor which had extended anteriorly to the nasal cavity without invasion. Twenty-five patients (78 %) demonstrated cervical lymphadenopathy. Patients with type 1, type 2 b and type 3 spread had frequent bilateral cervical lymphadenopathy; those with type 2 a had only ipsilateral lymphadenopathy. There was statistical significance (P < 0.005) regarding the existence of contralateral lymphadenopathy with midline tumors as well as the absence of contralateral cervical lymphadenopathy with non-midline tumors. This study therefore suggests that the distribution of metastasized lymph nodes depends on the pattern of tumor extent at the primary site. (orig.)

  9. EUPORIAS: plans and preliminary results

    Science.gov (United States)

    Buontempo, C.

    2013-12-01

    Recent advances in our understanding and ability to forecast climate variability have meant that skilful predictions are beginning to be routinely made on seasonal to decadal (s2d) timescales. Such forecasts have the potential to be of great value to a wide range of decision-making, where outcomes are strongly influenced by variations in the climate. In 2012 the European Commission funded EUPORIAS, a four year long project to develop prototype end-to-end climate impact prediction services operating on a seasonal to decadal timescale, and assess their value in informing decision-making. EUPORIAS commenced on 1 November 2012, coordinated by the UK Met Office leading a consortium of 24 organisations representing world-class European climate research and climate service centres, expertise in impacts assessments and seasonal predictions, two United Nations agencies, specialists in new media, and commercial companies in climate-vulnerable sectors such as energy, water and tourism. The poster describes the setup of the project, its main outcome and some of the very preliminary results.

  10. Preliminary results of ANAIS-25

    CERN Document Server

    Amaré, J; Cuesta, C; García, E; Ginestra, C; Martínez, M; Oliván, M A; Ortigoza, Y; de Solórzano, A Ortiz; Pobes, C; Puimedón, J; Sarsa, M L; Villar, P; Villar, J A

    2013-01-01

    The ANAIS (Annual Modulation with NaI(Tl) Scintillators) experiment aims at the confirmation of the DAMA/LIBRA signal using the same target and technique at the Canfranc Underground Laboratory. 250 kg of ultrapure NaI(Tl) crystals will be used as a target, divided into 20 modules, each coupled to two photomultipliers. Two NaI(Tl) crystals of 12.5 kg each, grown by Alpha Spectra from a powder having a potassium level under the limit of our analytical techniques, form the ANAIS-25 set-up. The background contributions are being carefully studied and preliminary results are presented: their natural potassium content in the bulk has been quantified, as well as the uranium and thorium radioactive chains presence in the bulk through the discrimination of the corresponding alpha events by PSA, and due to the fast commissioning, the contribution from cosmogenic activated isotopes is clearly identified and their decay observed along the first months of data taking. Following the procedures established with ANAIS-0 and ...

  11. Feasibility study of single agent cisplatin and concurrent radiotherapy in Japanese patients with squamous cell carcinoma of the head and neck. Preliminary results

    International Nuclear Information System (INIS)

    Concurrent chemoradiotherapy with the single agent cisplatin (CDDP+RT) has been recognized worldwide as the standard treatment for unresectable locally advanced SCCHN. The objective of this study was to clarify the feasibility of CDDP+RT in Japanese patients. Patients with unresectable squamous cell carcinoma of the head and neck were given single daily fractionated radiation (70 Gy at 2 Gy/day) and chemotherapy consisting of a 2 h infusion of CDDP 100 mg/m2 on days 1, 22 and 43. The primary endpoint was the rate of completion of CDDP+RT. Between November 2005 and January 2007, 20 patients were enrolled, 19 males and one female with a median age of 61.5 years (range 50-74). One patient had recurrent unresectable disease after surgery and the remaining 19 had stage IV disease. No grade 4 hematologic toxicities were observed. The incidence of grade 3 mucositis was 55% and no treatment-related death occurred. Full-dose irradiation was performed in all patients, with a median duration of radiotherapy of 50 days (range 48-54). Although all patients received the first two administrations of CDDP, the third dose was administed in 17 patients (85%). The rate of completion of CDDP+RT was 85% and the dose intensity of CDDP was 28.9 mg/m2/week (relative dose intensity 89%). Overall complete response rate was 50% and the rate of primary complete response was 90%. Concurrent chemoradiation therapy with the standard dose of CDDP is feasible in Japanese patients. Treatment modification based on racial differences is not necessary. (author)

  12. Preliminary Results Towards Contract Monitorability

    OpenAIRE

    Vella, Annalizz; Francalanza, Adrian

    2016-01-01

    This paper discusses preliminary investigations on the monitorability of contracts for web service descriptions. There are settings where servers do not guarantee statically whether they satisfy some specified contract, which forces the client (i.e., the entity interacting with the server) to perform dynamic checks. This scenario may be viewed as an instance of Runtime Verification, where a pertinent question is whether contracts can be monitored for adequately at runtime, otherwise stated as...

  13. A Phase II Study of Bevacizumab in Combination With Definitive Radiotherapy and Cisplatin Chemotherapy in Untreated Patients With Locally Advanced Cervical Carcinoma: Preliminary Results of RTOG 0417

    Energy Technology Data Exchange (ETDEWEB)

    Schefter, Tracey E., E-mail: tracey.schefter@ucdenver.edu [University of Colorado-Denver, Aurora, CO (United States); Winter, Kathryn [RTOG Statistical Center, Philadelphia, PA (United States); Kwon, Janice S. [University of British Columbia and BC Cancer Agency, Vancouver, BC (Canada); Stuhr, Kelly [Anschutz Cancer Pavilion, Aurora, CO (United States); Balaraj, Khalid [King Faisal Specialist Hospital and Research Centre, Riyadh (Saudi Arabia); Yaremko, Brian P. [University of Western Ontario, London Regional Cancer Program, London, ON (Canada); Small, William [The Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL (United States); Gaffney, David K. [University of Utah Health Science Center, Salt Lake City, UT (United States)

    2012-07-15

    Purpose: Concurrent cisplatin-based chemoradiotherapy (CRT) is the standard treatment for locally advanced cervical cancer. RTOG 0417 was a Phase II study exploring the safety and efficacy of the addition of bevacizumab to standard CRT. Methods and Materials: Eligible patients with bulky tumors (Stage IB-IIIB) were treated with once-weekly cisplatin (40 mg/m{sup 2}) chemotherapy and standard pelvic radiotherapy and brachytherapy. Bevacizumab was administered at 10 mg/kg intravenously every 2 weeks for three cycles. Treatment-related serious adverse event (SAE) and other adverse event (AE) rates within the first 90 days from treatment start were determined. Treatment-related SAEs were defined as any Grade {>=}4 vaginal bleeding or thrombotic event or Grade {>=}3 arterial event, gastrointestinal (GI) bleeding, or bowel/bladder perforation, or any Grade 5 treatment-related death. Treatment-related AEs included all SAEs and Grade 3 or 4 GI toxicity persisting for >2 weeks despite medical intervention, Grade 4 neutropenia or leukopenia persisting for >7 days, febrile neutropenia, Grade 3 or 4 other hematologic toxicity, and Grade 3 or 4 GI, renal, cardiac, pulmonary, hepatic, or neurologic AEs. All AEs were scored using the National Cancer Institute Common Terminology Criteria (CTCAE) v 3.0 (MedDRA version 6.0). Results: A total of 60 patients from 28 institutions were enrolled between 2006 and 2009, and of these, 49 patients were evaluable. The median follow-up was 12.4 months (range, 4.6-31.4 months).The median age was 45 years (range, 22-80 years). Most patients had FIGO Stage IIB (63%) and were of Zubrod performance status of 0 (67%). 80% of cases were squamous. There were no treatment-related SAEs. There were 15 (31%) protocol-specified treatment-related AEs within 90 days of treatment start; the most common were hematologic (12/15; 80%). 18 (37%) occurred during treatment or follow-up at any time. 37 of the 49 patients (76%) had cisplatin and bevacizumab

  14. Results of surgical therapy for lung carcinoma.

    Science.gov (United States)

    Paris, F; Padilla, J; Tarazona, V; Blasco, E; Canto, A; Pastor, J; Zarza, A G

    1979-01-01

    A series of 300 pulmonary resections in patients with lung carcinoma is presented. Total survival rate of the series since the operation, including surgical mortality, was 33% at 3 years and 24% at 5 years. The survival rate and surgical criteria were correlated, having better results when standard surgery was performed. The authors emphasize that the surgical figures of the series are of great value as the surgical indications were large and nonselective, with 85% of resectability in the thoracotomies. PMID:229985

  15. Rare earth optogalvanic spectroscopy: preliminary results

    International Nuclear Information System (INIS)

    The IEAv has special interest in the studies of rare earth isotope applications in laser medium and integrated optics as well as aerospace research. We are starting to work with Ytterbium, Erbium, Dysprosium and Neodymium laser selective photoionization research. This paper describes the preliminary results of emission and optogalvanic spectroscopy obtained from a Neodymium hollow cathode lamps. Furthermore these results were used to setup our laser systems to work to leads a Nd isotopes selective laser photoionization. (author)

  16. Preliminary results of ground-motion characteristics

    Directory of Open Access Journals (Sweden)

    Francesca Bozzoni

    2012-10-01

    Full Text Available The preliminary results are presented herein for the engineering applications of the characteristics of the ground motion induced by the May 20, 2012, Emilia earthquake. Shake maps are computed to provide estimates of the spatial distribution of the induced ground motion. The signals recorded at the Mirandola (MRN station, the closest to the epicenter, have been processed to obtain acceleration, velocity and displacement response spectra. Ground-motion parameters from the MRN recordings are compared with the corresponding estimates from recent ground-motion prediction equations, and with the spectra prescribed by the current Italian Building Code for different return periods. The records from the MRN station are used to plot the particle orbit (hodogram described by the waveform. The availability of results from geotechnical field tests that were performed at a few sites in the Municipality of Mirandola prior to this earthquake of May 2012 has allowed preliminary assessment of the ground response. The amplification effects at Mirandola are estimated using fully stochastic site-response analyses. The seismic input comprises seven actual records that are compatible with the Italian code-based spectrum that refers to a 475-year return period. The computed acceleration response spectrum and the associated dispersion are compared to the spectra calculated from the recordings of the MRN station. Good agreement is obtained for periods up to 1 s, especially for the peak ground acceleration. For the other periods, the spectral acceleration of the MRN recordings exceeds that of the computed spectra.

  17. Breakthrough propulsion physics workshop preliminary results

    International Nuclear Information System (INIS)

    In August, 1997, a NASA workshop was held to assess the prospects emerging from physics that might lead to creating the ultimate breakthroughs in space transportation: propulsion that requires no propellant mass, attaining the maximum transit speeds physically possible, and breakthrough methods of energy production to power such devices. Because these propulsion goals are presumably far from fruition, a special emphasis was to identify affordable, near-term, and credible research that could make measurable progress toward these propulsion goals. Experiments and theories were discussed regarding the coupling of gravity and electromagnetism, vacuum fluctuation energy, warp drives and wormholes, and superluminal quantum tunneling. Preliminary results of this workshop are presented, along with the status of the Breakthrough Propulsion Physics program that conducted this workshop

  18. Breakthrough Propulsion Physics Workshop Preliminary Results

    Science.gov (United States)

    Millis, Marc G.

    1997-01-01

    In August, 1997, a NASA workshop was held to assess the prospects emerging from physics that might lead to creating the ultimate breakthroughs in space transportation: propulsion that requires no propellant mass, attaining the maximum transit speeds physically possible, and breakthrough methods of energy production to power such devices. Because these propulsion goals are presumably far from fruition, a special emphasis was to identify affordable, near-term, and credible research that could make measurable progress toward these propulsion goals. Experiments and theories were discussed regarding the coupling of gravity and electromagnetism, vacuum fluctuation energy, warp drives and wormholes, and superluminal quantum tunneling. Preliminary results of this workshop are presented, along with the status of the Breakthrough Propulsion Physics program that conducted this workshop.

  19. Preliminary results from an advanced lighting controlstestbed

    Energy Technology Data Exchange (ETDEWEB)

    Avery, Douglas; Jennings, Judity; Rubinstein, Francis

    1998-03-01

    Preliminary results from a large-scale testbed of advanced lighting control technologies at the Phillip Burton Federal Building at 450 Golden Gate Ave. in San Francisco are presented. The first year objective of this project is to determine the sustainable energy savings and cost-effectiveness of different lighting control technologies compared to a portion of the building where only minimal controls are installed. The paper presents the analyzed results from six months of tests focused on accurately characterizing the energy savings potential of one type of daylight-linked lighting controls compared to the lighting in similar open-planned areas without dimming controls. After analyzing a half year;s data, we determined that the annual energy savings for this type of daylight- linked controls was 41% and 30% for the outer rows of lights on the South and North sides of the building, respectively. The annual energy savings dropped to 22% and 16% for the second row of lights for the South and North, respectively, and was negligible for the third rows of lights.

  20. Modeling Malaysia's Energy System: Some Preliminary Results

    Directory of Open Access Journals (Sweden)

    Ahmad M. Yusof

    2011-01-01

    Full Text Available Problem statement: The current dynamic and fragile world energy environment necessitates the development of new energy model that solely caters to analyze Malaysia’s energy scenarios. Approach: The model is a network flow model that traces the flow of energy carriers from its sources (import and mining through some conversion and transformation processes for the production of energy products to final destinations (energy demand sectors. The integration to the economic sectors is done exogeneously by specifying the annual sectoral energy demand levels. The model in turn optimizes the energy variables for a specified objective function to meet those demands. Results: By minimizing the inter temporal petroleum product imports for the crude oil system the annual extraction level of Tapis blend is projected at 579600 barrels per day. The aggregate demand for petroleum products is projected to grow at 2.1% year-1 while motor gasoline and diesel constitute 42 and 38% of the petroleum products demands mix respectively over the 5 year planning period. Petroleum products import is expected to grow at 6.0% year-1. Conclusion: The preliminary results indicate that the model performs as expected. Thus other types of energy carriers such as natural gas, coal and biomass will be added to the energy system for the overall development of Malaysia energy model.

  1. Viking first encounter of phobos: preliminary results.

    Science.gov (United States)

    Tolson, R H; Duxbury, T C; Born, G H; Christensen, E J; Diehl, R E; Farless, D; Hildebrand, C E; Mitchell, R T; Molko, P M; Morabito, L A; Palluconi, F D; Reichert, R J; Taraji, H; Veverka, J; Neugebauer, G; Findlay, J T

    1978-01-01

    During the last 2 weeks of February 1977, an intensive scientific investigation of the martian satellite Phobos was conducted by the Viking Orbiter-1 (VO-1) spacecraft. More than 125 television pictures were obtained during this period and infrared observations were made. About 80 percent of the illuminated hemisphere was imaged at a resolution of about 30 meters. Higher resolution images of limited areas were also obtained. Flyby distances within 80 kilometers of the surface were achieved. An estimate of the mass of Phobos (GM) was obtained by observing the effect of Phobos's gravity on the orbit of VO-1 as sensed by Earth-based radiometric tracking. Preliminary results indicate a value of GM of 0.00066 +/- 0.00012 cubic kilometer per second squared (standard deviation of 3) and a mean density of about 1.9 +/- 0.6 gram per cubic centimeter (standard deviation of 3). This low density, together with the low albedo and the recently determined spectral reflectance, suggest that Phobos is compositionally similar to type I carbonaceous chondrites. Thus, either this object formed in the outer part of the asteroid belt or Lewis's theory that such material cannot condense at 1.5 astronomical units is incorrect. The data on Phobos obtained during this first encounter period are comparable in quantity to all of the data on Mars returned by Mariner flights 4, 6, and 7. PMID:17841954

  2. Endovascular repair of aortic aneurysm: Preliminary results

    Directory of Open Access Journals (Sweden)

    Davidović Lazar

    2009-01-01

    Full Text Available Introduction. Endovascular aneurysm repair (EVAR has been introduced into clinical practice at the beginning of the 90's of the last century. Because of economic, political and social problems during the last 25 years, the introduction of this procedure in Serbia was not possible. Objective. The aim of this study was to present preliminary experiences and results of the Clinic for Vascular Surgery of the Serbian Clinical Centre in Belgrade in endovascular treatment of thoracic and abdominal aortic aneurysms. Methods. The procedure was performed in 33 patients (3 female and 30 male, aged from 42 to 83 years. Ten patients had a descending thoracic aorta aneurysm (three atherosclerotic, four traumatic - three chronic and one acute as a part of polytrauma, one dissected, two penetrated atherosclerotic ulcers, while 23 patients had the abdominal aortic aneurysm, one ruptured and two isolated iliac artery aneurysms. The indications for EVAR were isthmic aneurismal localisation, aged over 80 years and associated comorbidity (cardiac, pulmonary and cerebrovasular diseases, previous thoracotomy or multiple laparotomies associated with abdominal infection, idiopatic thrombocitopaenia. All of these patients had three or more risk factors. The diagnosis was established using duplex ultrasonography, angiography and MSCT. In the case of thoracic aneurysm, a Medtronic-Valiant® endovascular stent graft was implanted, while for the abdominal aortic aneurysm Medtronic-Talent® endovascular stent grafts with delivery systems were used. In three patients, following EVAR a surgical repair of the femoral artery aneurysm was performed, and in another three patients femoro-femoral cross over bypass followed implantation of aortouniiliac stent graft. Results. During procedure and follow-up period (mean 1.6 years, there were: one death, one conversion, one endoleak type 1, six patients with endoleak type 2 that disappeared during the follow-up period, one early graft

  3. Maxillary sinus carcinoma: result of radiation therapy

    International Nuclear Information System (INIS)

    This hundred and sixteen patients with carcinoma of the maxillary sinus received primary therapy consisting of external beam irradiation alone or in combination with surgery and/or chemotherapy at the Department of Radiology, Tokyo Medical and Dental University Hospital, between 1953 and 1982. In our institution, methods of treating cancer of the maxillary sinus have been changed from time to time and showed different control rates and clinical courses. An actuarial 10-year survival rate of 21% has been obtained by the megavoltage irradiation alone as well as 34% actuarial 10-year survival rate by megavoltage irradiation with surgery. After the introduction of conservative surgery followed by conventional trimodal combination therapy, the local control rate has been improved. The amount of functional, cosmetic, and brain damages have been remarkably decreased by this mode of therapy. The actuarial five year survival rate was 67%. In addition, along with the improvement of the local control rate, the control of nodal and distant organ metastases have been emerging as one of the important contributions to the prognosis of this disease

  4. Preliminary results of toxicity, biochemical and histological response in patients with carcinoma of the prostate treated on a prospective dose-finding study with 3-D conformal mixed neutron and photon irradiation

    International Nuclear Information System (INIS)

    Purpose: To determine the incidence of chronic toxicity and the probabilities of biochemical and histologic response among patients with carcinoma of the prostate (CaP) treated with 3D conformal mixed neutron and photon irradiation with or without neo-adjuvant hormonal therapy. Materials and Methods: Between November 1991 and December 1994, 150 patients with prostate cancer were entered on 3 prospective dose-finding studies of conformal mixed neutron and photon irradiation. The neutrons were produced from a superconducting cyclotron with a 48 MeV deuteron beam. Patients with low stage, low to intermediate grade CaP (T1-2, Nx,M0, Gleason score ≤ 7) were treated with conformal photon irradiation (38 PhGy) plus non-axial conformal neutron irradiation to 9 Neutron Gy (51 pts) or 10 N Gy (52 patients). Forty-seven patients with locally advanced CaP (T3-4, N0-N1, M0, Gleason score ≥ 8) received 15 N Gy plus 18 Ph Gy to the prostate and 9 NGy + 18 PhGy to the pelvic lymph nodes. The mean pre-treatment PSA values for the two groups were 11.3 and 46.1 ng/ml, respectively. Major prognostic factors were balanced between the 78 patients who did and the 72 who did not receive neo-adjuvant hormonal therapy. Toxicity was scored according to the RTOG toxicity scale. The median follow-up was 12 months. Results: The overall incidence of gastrointestinal (GI) toxicity at 12 months was: grade (0(I)) 92.5%, grade II = 7%, grade III = 1.5%, grade IV = 0%. The overall incidence of genitourinary (GU) toxicity at 12 months was: grade (0(I)) = 94%, grade II = 3%, grade III = 3%, grade IV = 0%. Grade II skin toxicity was recorded in 15% of patients. Stiffness in flexing or abducting the hips at doses of 9 or 10 and 15 NGy was 20% and 42% respectively (p < 0.05). Severe hip stiffness was seen in 0% and 26% of patients, respectively (p < 0.05). At 9 or 10 NGy, 2.6% of patients had grade II GI or GU complications compared with 21% grade II and III at 15 NGy (p < 0.05). Potency was retained

  5. The Result of Radiotherapy in Esophageal Carcinoma

    International Nuclear Information System (INIS)

    During the period between March 1983 and December 1990, 74 patients with esophageal carcinoma(EC) were treated with radiation therapy(RT) at the Department of Therapeutic Radiology, Kangnam St. Mary Hospital, Catholic University Medical College. Of these, 6 patients were lost to follow-up, and 13 patients were interrupted. So the remaining 55 patients were analyzed, retrospectively. 32 patients were irradiated with curative aim, 12 patients with palliative intent, 10 patients postoperatively, and 1 patient pre- and post-operatively. Among these 55 patients, 28 patients were treated with chemoradiation modality, and 27 patients with RT alone. All patients were followed for a minimum of 20 months or Hntil death. of 32 patients irradiated by curative aim, 22 patients(69%) showed partial remission (PR), 6 patients(19%) complete remission(CR). Overall mean survival and two-year survival rate were 15.6 months and 22%. With respect to sex, age, pathologic differentiation, tumor location, tumor size, stage, RT aim, RT response, RT dose, use of chemotherapy and functional categories(FC) of dysphagia at initiation of RT and at finishing RT : Tumor size, stage, RT response had great influences on prognosis and FC at finishing RT had a slight influence on prognosis. Especially, the mean survival and 2-year survival rate in patients with postoperative RT were 24.7 months and 63%, which could be compared with 29.1 months and 43% in radically treated patients with CR. And the mean survival duration and 2-year survival rate in patients irradiated with doses more than 60 Gy were 22.4 months and 29%, and 50-60 Gy were 12.2 months and 12%, respectively. However, no significant difference was shown statistically. Among 12 patients treated with palliative intent, 9 patients (75%) had good improvement in dysphagia and the mean duration of palliative response was 10.6 months

  6. Brachytherapy in Lip Carcinoma: Long-Term Results

    International Nuclear Information System (INIS)

    Purpose: The aim of this study was to evaluate the effectiveness of low-dose-rate brachytherapy for local control and relapse-free survival in squamous cell and basal cell carcinomas of the lips. We compared two groups: one with tumors on the skin and the other with tumors on the lip. Patients and methods: All patients had been treated at Claudius Regaud Cancer Centre from 1990 to 2008 for squamous cell or basal cell carcinoma. Low-dose-rate brachytherapy was performed with iridium 192 wires according to the Paris system rules. On average, the dose delivered was 65 Gy. Results: 172 consecutive patients were included in our study; 69 had skin carcinoma (squamous cell or basal cell), and 92 had squamous cell mucosal carcinoma. The average follow-up time was 5.4 years. In the skin cancer group, there were five local recurrences and one lymph node recurrence. In the mucosal cancer group, there were ten local recurrences and five lymph node recurrences. The 8-year relapse-free survival for the entire population was 80%. The 8-year relapse-free survival was 85% for skin carcinoma 75% for mucosal carcinoma, with no significant difference between groups. The functional results were satisfactory for 99% of patients, and the cosmetic results were satisfactory for 92%. Maximal toxicity observed was Grade 2. Conclusions: Low-dose-rate brachytherapy can be used to treat lip carcinomas at Stages T1 and T2 as the only treatment with excellent results for local control and relapse-free survival. The benefits of brachytherapy are also cosmetic and functional, with 91% of patients having no side effects.

  7. Brachytherapy in Lip Carcinoma: Long-Term Results

    Energy Technology Data Exchange (ETDEWEB)

    Guibert, Mireille, E-mail: mireilleguib@voila.fr [Department of Head and Neck Surgery, Larrey Hospital, Toulouse (France); David, Isabelle [Department of Radiation Oncology, Claudius Regaud Institut, Toulouse (France); Vergez, Sebastien [Department of Head and Neck Surgery, Larrey Hospital, Toulouse (France); Rives, Michel [Department of Radiation Oncology, Claudius Regaud Institut, Toulouse (France); Filleron, Thomas [Department of Epidemiology, Claudius Regaud Institut, Toulouse (France); Bonnet, Jacques; Delannes, Martine [Department of Radiation Oncology, Claudius Regaud Institut, Toulouse (France)

    2011-12-01

    Purpose: The aim of this study was to evaluate the effectiveness of low-dose-rate brachytherapy for local control and relapse-free survival in squamous cell and basal cell carcinomas of the lips. We compared two groups: one with tumors on the skin and the other with tumors on the lip. Patients and methods: All patients had been treated at Claudius Regaud Cancer Centre from 1990 to 2008 for squamous cell or basal cell carcinoma. Low-dose-rate brachytherapy was performed with iridium 192 wires according to the Paris system rules. On average, the dose delivered was 65 Gy. Results: 172 consecutive patients were included in our study; 69 had skin carcinoma (squamous cell or basal cell), and 92 had squamous cell mucosal carcinoma. The average follow-up time was 5.4 years. In the skin cancer group, there were five local recurrences and one lymph node recurrence. In the mucosal cancer group, there were ten local recurrences and five lymph node recurrences. The 8-year relapse-free survival for the entire population was 80%. The 8-year relapse-free survival was 85% for skin carcinoma 75% for mucosal carcinoma, with no significant difference between groups. The functional results were satisfactory for 99% of patients, and the cosmetic results were satisfactory for 92%. Maximal toxicity observed was Grade 2. Conclusions: Low-dose-rate brachytherapy can be used to treat lip carcinomas at Stages T1 and T2 as the only treatment with excellent results for local control and relapse-free survival. The benefits of brachytherapy are also cosmetic and functional, with 91% of patients having no side effects.

  8. Topology and phase transitions I. Preliminary results

    International Nuclear Information System (INIS)

    In this first paper, we demonstrate a theorem that establishes a first step toward proving a necessary topological condition for the occurrence of first- or second-order phase transitions: we prove that the topology of certain submanifolds of configuration space must necessarily change at the phase transition point. The theorem applies to smooth, finite-range and confining potentials V bounded below, describing systems confined in finite regions of space with continuously varying coordinates. The relevant configuration space submanifolds are both the level sets {Σv:=VN-1(v)}velementofR of the potential function VN and the configuration space submanifolds enclosed by the Σv defined by {Mv:=VN-1((-∞,v])}velementofR, which are labeled by the potential energy value v, and where N is the number of degrees of freedom. The proof of the theorem proceeds by showing that, under the assumption of diffeomorphicity of the equipotential hypersurfaces {Σv}velementofR, as well as of the {Mv}velementofR, in an arbitrary interval of values for v-bar =v/N, the Helmholtz free energy is uniformly convergent in N to its thermodynamic limit, at least within the class of twice differentiable functions, in the corresponding interval of temperature. This preliminary theorem is essential to prove another theorem-in (paper II)-which makes a stronger statement about the relevance of topology for phase transitions

  9. Magnetic Resonance Elastography of Liver Tumors- Preliminary Results

    Science.gov (United States)

    Venkatesh, Sudhakar K; Yin, Meng; Glockner, James F; Takahashi, Naoki; Araoz, Philip A; Talwalkar, Jayant A; Ehman, Richard L

    2010-01-01

    Aim To evaluate the potential value of magnetic resonance elastography (MRE) for characterizing solid liver tumors. Materials and Methods Forty-four liver tumors (metastases-14, hepatocellular carcinoma- 12, hemangioma-9, cholangiocarcinoma-5, focal nodular hyperplasia-3, and hepatic adenoma-1) were evaluated with MRE. MRE was performed on a 1.5 T scanner with a modified phase-contrast, gradient echo sequence to collect axial wave images sensitized along the through-plane motion direction. The tumors were identified in T2-, T1-weighted and gadolinium enhanced T1-weighted images and the MRE images were obtained through the tumor. A stiffness map (elastogram) was generated by an automated process using an inversion algorithm. The mean shear stiffness of the tumor was calculated using a manually specified region of interest placed over the tumor in the stiffness map. The stiffness value of non-tumor bearing hepatic parenchyma was also calculated. Statistical analysis was performed on the stiffness values for differentiation between normal liver, fibrotic liver, benign tumors and malignant tumors. Results Malignant liver tumors had significantly higher mean shear stiffness than benign tumors, fibrotic liver and normal liver (10.1kPa vs. 2.7kpa (p<0.001), vs. 5.9kPa (p<0.001) and vs. 2.3kPa (p<0.001) respectively). Fibrotic livers had stiffness values overlapping both the benign and malignant tumors. Cut-off values of 5kPa accurately differentiate malignant tumors from benign tumors and normal liver parenchyma in this preliminary investigation. Conclusions MR elastography is a promising, non-invasive technique for assessing solid liver tumors. MRE may provide new, quantitative tissue characterization parameters for differentiating benign and malignant liver tumors. PMID:18492904

  10. Treatment of anal canal carcinoma with concomitant radiotherapy and chemotherapy. Preliminary results from Hospital do Cancer A.C. Camargo, Sao Paulo State, Brazil; Tratamento do carcinoma do canal anal com radioterapia e quimioterapia concomitantes. Resultados preliminares do Hospital do Cancer A.C. Camargo

    Energy Technology Data Exchange (ETDEWEB)

    Lima Junior, Carlos Genesio Bezerra; Ferrigno, Robson; Salvajoli, Joao Victor [Hospital do Cancer A.C. Camargo, Sao Paulo, SP (Brazil). Dept. de Radioterapia]. E-mail: rferrigno@uol.com.br; David Filho, Waldec Jose [Hospital do Cancer A.C. Camargo, Sao Paulo, SP (Brazil). Dept. de Oncologia Clinica; Rossi, Benedito Mauro; Lopes, Ademar [Hospital do Cancer A.C. Camargo, Sao Paulo, SP (Brazil). Dept. de Cirurgia Pelvica

    2001-02-01

    Background: To report our results of anal canal carcinoma treatment with concomitant radiotherapy and chemotherapy. Method: From January 1992 to May 1998, 24 patients with anatomo-pathologic diagnosis of anal canal carcinoma were treated. Age ranged from 35 years old to 74 years old median of 59 years old. Female and male ratio was 3:1. The number of patients per stage was: I - 1, II - 13, III - 9 and IV - 1. Radiotherapy was delivered with doses of 45 Gy at the whole pelvis with 4 MeV Linear Accelerator followed by boost to the anal canal until 55 Gy through direct field at Cobalt unit. Chemotherapy consisted of 5-FU (1000 mg/m{sup 2}) and Mitomycin C (10 mg/m{sup 2}) during the first and last five days of radiotherapy. Results: The mean follow-up period was 34 months. Complete response was observed in 23 (95,8%) patients. Fourteen (58,3%) patients are alive with no cancer, 3 (12%) are alive with cancer, 5 (20,8%) died with cancer and 1 (4,2%) died with no evidence of cancer. Local recurrences occurred in 5 (20,8%) and distant metastasis in 4 (16,6%). All patients with local recurrence were salvaged with abdominal perineal resection. Sphincter function was preserved in 18 (75%) patients. Acute and chronic complications were observed in 19 (79,2%) and in 9 (37,5%) patients, respectively. Conclusions: The treatment was effective in terms of local control and sphincter preservation, but a with high incidence of acute and late complications. Lower dose of radiation at the whole pelvis should be a reasonable approach to improve acute and late side effects. A larger number of patients and a longer follow-up will give more information about this treatment approach. (author)

  11. A randomized phase II/III study of adverse events between sequential (SEQ) versus simultaneous integrated boost (SIB) intensity modulated radiation therapy (IMRT) in nasopharyngeal carcinoma; preliminary result on acute adverse events

    International Nuclear Information System (INIS)

    To investigate acute and late toxicities comparing sequential (SEQ-IMRT) versus simultaneous integrated boost intensity modulated radiotherapy (SIB-IMRT) in nasopharyngeal carcinoma (NPC) patients. Newly diagnosed stage I-IVB NPC patients were randomized to receive SEQ-IMRT or SIB-IMRT, with or without chemotherapy. SEQ-IMRT consisted of two sequential radiation treatment plans: 2Gy x 25 fractions to low-risk planning target volume (PTV-LR) followed by 2Gy x 10 fractions to high-risk planning target volume (PTV-HR). In contrast, SIB-IMRT consisted of only one treatment plan: 2.12Gy and 1.7Gy x 33 fractions to PTV-HR and PTV-LR, respectively. Toxicities were evaluated according to CTCAE version 4.0. Between October 2010 and November 2013, 122 eligible patients were randomized between SEQ-IMRT (54 patients) and SIB-IMRT (68 patients). With median follow-up time of 16.8 months, there was no significant difference in toxicities between the two IMRT techniques. During chemoradiation, the most common grade 3–5 acute toxicities were mucositis (15.4 % vs 13.6 %, SEQ vs SIB, p = 0.788) followed by dysphagia (9.6 % vs 9.1 %, p = 1.000) and xerostomia (9.6 % vs 7.6 %, p = 0.748). During the adjuvant chemotherapy period, 25.6 % and 32.7 % experienced grade 3 weight loss in SEQ-IMRT and SIB-IMRT (p = 0.459). One-year overall survival (OS) and progression-free survival (PFS) were 95.8 % and 95.5 % in SEQ-IMRT and 98 % and 90.2 % in SIB-IMRT, respectively (p = 0.472 for OS and 0.069 for PFS). This randomized, phase II/III trial comparing SIB-IMRT versus SEQ-IMRT in NPC showed no statistically significant difference between both IMRT techniques in terms of acute adverse events. Short-term tumor control and survival outcome were promising

  12. The results of postoperative radiotherapy for hypopharyngeal carcinoma

    International Nuclear Information System (INIS)

    This study was carried out to confirm clinical values and limitations of postoperative radiotherapy for hypopharyngeal carcinoma, to evaluate various prognostic factors which may affect to the treatment results and to use these results as fundamental data for making a new treatment strategy. A retrospective analysis was performed on 64 previously untreated patients with squamous cell carcinoma of the hypopharynx, seen between 1988 and 1999 at Pusan National University Hospital. Most of patients were treated by laryngopharyngectomy and neck dissection followed by conventional fractionated postoperative radiotherapy on surgical bed and cervical nodal areas. The five-year overall survival rate and cause-specific survival rate were 42.2 percent and 51.6 percent, respectively. Univariate analysis of various clinical and pathologic factors confirmed the overall stage, TN-stage, secondary primary cancers, surgical positive margin, nodal extracapsular extension, total radiation doses as significant prognostic factors of hypopharyngeal carcinomas. But in multivariate analysis. TN-stage, surgical positive margin and extracapsular extension were only statistically significant. In resectable cases of hypopharyngeal carcinoma, combined surgery and postoperative radiotherapy obtained good treatment results, even though sacrificing the function of larynx and pharynx. But in advanced and unresectable cases, with respect to survivals and quality of life issues, we were able to confirm some limitations of combined therapy. So we recommend that comparative of recent various chemo-radiotherapy methods and advanced radiotherapy techniques with these data should be needed

  13. Preliminary results of impeller design modifications

    International Nuclear Information System (INIS)

    Power consumption in the oil mixing process is very much affected by the impeller design. Minor modification on the impeller design might result in better mixing and less energy consumption. This paper reports an early stage of applying the observation technique to modify three standard impellers, namely the Pitched blade turbine impeller, the CHEMSHEAR impeller and the Vertical Flat-Blade Turbine Impeller. The advantages and disadvantages of these three impellers were analyzed; accordingly minor modification on the impeller design is adopted. The CFD tool is used to evaluate one of the modified impellers; results indicated that the modified impeller achieves better fluid dispersion.

  14. Danish Anaesthesia Allergy Centre - preliminary results

    DEFF Research Database (Denmark)

    Garvey, L H; Roed-Petersen, J; Menné, T;

    2001-01-01

    cases. Patients are tested with all substances they were exposed to, including antibiotics, colloids, latex and chlorhexidine. RESULTS: A total of 68 patients have been referred to date (July 2001) and 36 have completed investigations. Positive test results were mainly seen in patients with more severe...... reactions, and there were more men than women in the group with the most severe reactions. Six patients had positive specific IgE, three for penicillin, two for latex and one for thiopental. In all, 21 patients had positive skin tests to various substances, of whom four men with anaphylactic shock tested...

  15. Preliminary results of steel containment vessel model test

    Energy Technology Data Exchange (ETDEWEB)

    Luk, V.K.; Hessheimer, M.F. [Sandia National Labs., Albuquerque, NM (United States); Matsumoto, T.; Komine, K.; Arai, S. [Nuclear Power Engineering Corp., Tokyo (Japan); Costello, J.F. [Nuclear Regulatory Commission, Washington, DC (United States)

    1998-04-01

    A high pressure test of a mixed-scaled model (1:10 in geometry and 1:4 in shell thickness) of a steel containment vessel (SCV), representing an improved boiling water reactor (BWR) Mark II containment, was conducted on December 11--12, 1996 at Sandia National Laboratories. This paper describes the preliminary results of the high pressure test. In addition, the preliminary post-test measurement data and the preliminary comparison of test data with pretest analysis predictions are also presented.

  16. Viking magnetic properties investigation: preliminary results.

    Science.gov (United States)

    Hargraves, R B; Collinson, D W; Spitzer, C R

    1976-10-01

    Three permanent magnet arrays are aboard the Viking lander. By sol 35, one array, fixed on a photometric reference test chart on top of the lander, has clearly attracted magnetic particles from airborne dust; two other magnet arrays, one strong and one weak, incorporated in the backhoe of the surface sampler, have both extracted considerable magnetic mineral from the surface as a result of nine insertions associated with sample acquisition. The loose martian surface material around the landing site is judged to contain 3 to 7 percent highly magnetic mineral which, pending spectrophotometric study, is thought to be mainly magnetite. PMID:17793086

  17. Viking magnetic properties investigation - Preliminary results

    Science.gov (United States)

    Hargraves, R. B.; Collinson, D. W.; Spitzer, C. R.

    1976-01-01

    Three permanent-magnet arrays are aboard the Viking lander. By sol 35, one array, fixed on a photometric reference test chart on top of the lander, has clearly attracted magnetic particles from airborne dust; two other magnet arrays, one strong and one weak, incorporated in the backhoe of the surface sampler, have both extracted considerable magnetic mineral from the surface as a result of nine insertions associated with sample acquisition. The loose Martian surface material around the landing site is judged to contain 3 to 7 per cent highly magnetic mineral which, pending spectrophotometric study, is thought to be mainly magnetite.

  18. Medical Radioisotope Data Survey: 2002 Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Siciliano, Edward R.

    2004-06-23

    A limited, but accurate amount of detailed information about the radioactive isotopes used in the U.S. for medical procedures was collected from a local hospital and from a recent report on the U.S. Radiopharmaceutical Markets. These data included the total number of procedures, the specific types of procedures, the specific radioisotopes used in these procedures, and the dosage administered per procedure. The information from these sources was compiled, assessed, pruned, and then merged into a single, comprehensive and consistent set of results presented in this report. (PIET-43471-TM-197)

  19. Discovery program for bright quasars: preliminary results

    International Nuclear Information System (INIS)

    A program has been undertaken to obtain a complete sample of bright quasars on the basis of ultraviolet color excess. Spectroscopic examination of candidates selected from two-color Schmidt telescope films has yielded four new quasars brighter than B = 16/sup m/5, with the candidate list containing two more previously identified. Magnitudes, color indices, and redshifts are presented for the new discoveries, along with positions and finding charts. Although the sample is not yet complete, these first results suggest that bright quasars have a low surface density

  20. Voice change after radiotherapy: some preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Colton, R.H.; Sagerman, R.H.; Chung, C.T.; Yu, Y.W.; Reed, G.F.

    1978-06-01

    A one-third octave spectral analysis was performed on two sentences spoken by 5 patients with laryngeal cancer, 5 with head/neck cancer not involving the vocal cords, and 12 normal subjects. Recordings were made prior to and at weekly intervals during radiotherapy as well as at periodic intervals post-treatment. Patients with laryngeal cancer exhibited lower spectral levels than normal throughout radiotherapy as well as several months post-treatment. By one year after treatment, the spectral levels of these patients were largely in the normal range. Patients with head/neck cancer not involving the vocal cords exhibited greater than normal sound pressure levels throughout most of the spectrum. These levels remained high even at one month post-treatment. Irradiation of normal vocal cord tissue also seems to result in higher spectral levels.

  1. Modelling Extortion Racket Systems: Preliminary Results

    Science.gov (United States)

    Nardin, Luis G.; Andrighetto, Giulia; Székely, Áron; Conte, Rosaria

    Mafias are highly powerful and deeply entrenched organised criminal groups that cause both economic and social damage. Overcoming, or at least limiting, their harmful effects is a societally beneficial objective, which renders its dynamics understanding an objective of both scientific and political interests. We propose an agent-based simulation model aimed at understanding how independent and combined effects of legal and social norm-based processes help to counter mafias. Our results show that legal processes are effective in directly countering mafias by reducing their activities and changing the behaviour of the rest of population, yet they are not able to change people's mind-set that renders the change fragile. When combined with social norm-based processes, however, people's mind-set shifts towards a culture of legality rendering the observed behaviour resilient to change.

  2. Preliminary results of a PACS implementation

    Science.gov (United States)

    Kishore, Sheel; Khalsa, Satjeet S.; Seshadri, Sridhar B.; Arenson, Ronald L.

    1991-07-01

    The Radiology Department at the University of Pennsylvania is in the process of clinically testing the first phase of its PACS implementation. The first phase has been designed to support two Intensive Care Units, two GE SIGNA MR units and a Du Pont FD 2000 Film Digitizer. The entire system has been running clinically for about three months. Any PACS effort involves integrating software and hardware from different manufactures. Some of the equipment on a PACS network are often 'closed' and provide limited access. In addition, the entire PACS system is expected to provide uninterrupted service, have adequate throughput and ensure data integrity. By and large, these goals have been met. Clinical testing has provided valuable insights about system integration and highlighted areas of improvement in the system design. A detailed discussion of these results is presented.

  3. Emetophobia: preliminary results of an internet survey.

    Science.gov (United States)

    Lipsitz, J D; Fyer, A J; Paterniti, A; Klein, D F

    2001-01-01

    Through electronic mail, we surveyed members of an internet support group for emetophobia (fear of vomiting). Respondents were 50 women and 6 men with a mean age of 31 years. Results suggest that, for this sample, emetophobia is a disorder of early onset and chronic course, with highly persistent and intrusive symptoms. Emetophobia is implicated in social, home-marital, and occupational impairment and it causes significant constriction of leisure activities. Nearly half of women avoided or delayed becoming pregnant. About three quarters of respondents have eating rituals or significantly limit the foods they eat. Respondents describe other problems such as depression, panic attacks, social anxiety, compulsions, and frequent history of childhood separation anxiety. PMID:11668669

  4. Voice change after radiotherapy: some preliminary results

    International Nuclear Information System (INIS)

    A one-third octave spectral analysis was performed on two sentences spoken by 5 patients with laryngeal cancer, 5 with head/neck cancer not involving the vocal cords, and 12 normal subjects. Recordings were made prior to and at weekly intervals during radiotherapy as well as at periodic intervals post-treatment. Patients with laryngeal cancer exhibited lower spectral levels than normal throughout radiotherapy as well as several months post-treatment. By one year after treatment, the spectral levels of these patients were largely in the normal range. Patients with head/neck cancer not involving the vocal cords exhibited greater than normal sound pressure levels throughout most of the spectrum. These levels remained high even at one month post-treatment. Irradiation of normal vocal cord tissue also seems to result in higher spectral levels

  5. Renal imaging at 7 Tesla: preliminary results

    International Nuclear Information System (INIS)

    To investigate the feasibility of 7T MR imaging of the kidneys utilising a custom-built 8-channel transmit/receive radiofrequency body coil. In vivo unenhanced MR was performed in 8 healthy volunteers on a 7T whole-body MR system. After B0 shimming the following sequences were obtained: 1) 2D and 3D spoiled gradient-echo sequences (FLASH, VIBE), 2) T1-weighted 2D in and opposed phase 3) True-FISP imaging and 4) a T2-weighted turbo spin echo (TSE) sequence. Visual evaluation of the overall image quality was performed by two radiologists. Renal MRI at 7T was feasible in all eight subjects. Best image quality was found using T1-weighted gradient echo MRI, providing high anatomical details and excellent conspicuity of the non-enhanced vasculature. With successful shimming, B1 signal voids could be effectively reduced and/or shifted out of the region of interest in most sequence types. However, T2-weighted TSE imaging remained challenging and strongly impaired because of signal heterogeneities in three volunteers. The results demonstrate the feasibility and diagnostic potential of dedicated 7T renal imaging. Further optimisation of imaging sequences and dedicated RF coil concepts are expected to improve the acquisition quality and ultimately provide high clinical diagnostic value. (orig.)

  6. Preliminary results of stevia plant (Stevia rebaudiana

    Directory of Open Access Journals (Sweden)

    NOC FASLLIA

    2014-06-01

    Full Text Available The study was conducted at the experimental plots of the Agricultural Technology Transfer Center(ATTC Fushe - Kruja, from 2013 to 2014. The objectives of this study were, recognition with bio morphology of the growth and development of Stevios plant under conditions of our country. The study design consists of 30 plant pots planted with the STEVIAS. Indicators studied, were: time of planting, the beginning of growth, plant growth height in cm, number of brothers, number of branches in the main branch, the average number of leaves, total number of leaves. Planting was carried out on 20 February 2013, followed by the onset of growth on 3/25/2013 to 3/04/2014, ripening and harvest in September 5-10 October. At the end of the production these results were taken according to the study indicators. The height of the plant was carried 71.53 ± 11.08cm, depending on feeding conditions and illumination which according to requirements of this plant is one of the most dominant factors. The average number of brothers per branch is to 10.6 ± 2.4, which shows a high potential for stevia plant production. The average number of leaves per branch is 48.13 ± 9.26, and with a total leaves of 517. 03 ± 176.25, which are quantitative harvestable indicators of plant. Weight of plant was conducted at 49.46 ± 4.987gr.

  7. Evaluation of image quality and dose in thoracic spiral CT examination in patients with pulmonary carcinoma. Preliminary results; Evaluacion de la calidad de imagen y de la dosis en examenes de TC helicoidal de torax en pacientes con carcinoma de pulmon. Resultados preliminares

    Energy Technology Data Exchange (ETDEWEB)

    Moran-Blanco, L. M.; Rodriguez-Gonzalez, R.; Calzado-Cantera, A.; Arenas de Pablo, A.; Baeza-Trujillo, M.; Cuevas-Ibanez, A.; Garcia-Castano, B.; Gomez-Leon, N.; Turrero-Nogues, A.; Moran-Penco, P.

    2002-07-01

    We have applied criteria for CT quality defined in the European Guidelines to a samples of thoracic CT examinations for the indication of pulmonary carcinoma of 5 institutions of the Community of Madrid that have spiral CT equipment. The selected examinations have been evaluated independently by five radiologists to determine the degree of adherence to the quality criteria for image defined in the Guidelines s for examinations of general thorax. Dosimetric measurements carried out in parallel have served to estimate the values of CT (CTDI{sub w}) dose indices, dose-length product (DLP) and effective dose for every patient. The result show a high global adherence to the quality criteria (96%), with averages per institution being between 94% (in two institutions) and 98% (in three institutions). There are 10 of 16 criteria that are adhered to in all examinations of the sample: those which are not adhered to systematically are: two of visualization (1.1 and 1.4), with 92-96% fulfillment, and four of critical reproduction (2.6; 2.8; 2.9 and 2.10), with percentages of adherence between 91% and 96%. The average CTDI{sub w} values per institution are in the interval 12.9-19.1 mGy; those of DLP between 263 and 577 mGy cm and those of effective dose between 4.2 and 9.2 mSv. The DLP-image quality correlation in institutions with the best image quality was null in two of them and direct and moderate in the third. In both institutions with the poorest image: (Author) 20 refs.

  8. MRT monitoring of prostate carcinoma after cryosurgery: initial results

    International Nuclear Information System (INIS)

    Purpose: To assess the morphological changes in the prostate gland and adjacent tissue after cryosurgery by high resolution MRI in patients with histological proven prostatic carcinoma. Method: 15 patients (mean age 66 years) with histologically proven prostate carcinoma underwent T2- and contrast-enhanced T1-weighted high-resolution MRI examinations with fat suppression. Follow-up MRI with an identical imaging protocol were performed at different time intervals (24-72 h, 2-6, 12, 26-52 weeks). Results: Mean prostate volume had decreased by 30% in all patients 12-52 weeks after cryosurgery. After cryosurgery, zonal differentiation was lost in all patients with abnormalities in the periprostatic tissue in all patients, and rectal wall thickening in 47% of patients. Cryosugery-induced changes in the prostate could not be differentiated from tumour recurrence. Conclusion: High resolution MRI allows precise recognition of intraprostatic and adjacent tissue alterations after cryosurgery of prostatic carcinomas. However, reliable detection of tumour recurrence was impossible due to cryosurgically induced signal changes. (orig.)

  9. Connecticut Transit (CTTRANSIT) Fuel Cell Transit Bus: Preliminary Evaluation Results

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2008-10-01

    This report provides preliminary results from a National Renewable Energy Laboratory evaluation of a protoptye fuel cell transit bus operating at Connecticut Transit in Hartford. Included are descriptions of the planned fuel cell bus demonstration and equipment; early results and agency experience are also provided.

  10. Metal rich stars in omega Cen: preliminary FLAMES GTO results

    CERN Document Server

    Pancino, E

    2004-01-01

    I present preliminary results for a sample of ~700 red giants in omega Cen, observed during the Ital-FLAMES Consortium GTO time in May 2003, for the Bologna Project on omega Cen. Preliminary Fe and Ca abundances confirm previous results: while the metal-poor and intermediate populations show a normal halo alpha-enhancement of [alpha/Fe]=$+0.3, the most metal-rich stars show a significantly lower [alpha/Fe]=+0.1. If the metal-rich stars have evolved within the cluster in a process of self-enrichment, the only way to lower their alpha-enhancement would be SNe type Ia intervention.

  11. A PRELIMINARY STUDY ON SURVIVIN AND BCL-2 EXPRESSION IN CERVICAL CARCINOMAS

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Objective To study the expression of a novel inhibitor of apptosis and survivin in cervical carcinoma and its relationship to the expression of Bcl-2.Methods Using SP immunohistochemical technique, we examined the expression of survivin and Bcl-2 in 59 cervical invasive squamous cell carcinomas.Results Survivin was expressed in 41 of 59 cases(69.5%) of cervical carcinomas. In contrast, no expression of survivin in normal cervical tissues was observed. Overexpression of survivin was related to the tumor grade and clinical stage. Survivin positive cases were strongly associated with Bcl-2 expression(80% versus 35.7%;P<0.005).Conclusion Apoptosis inhibition by survivin abnormal expression, alone or in cooperation with Bcl-2, may participate in the onset and progression of cervical carcinoma. Survivin is a new diagnostic/therapeutic target in cervical cancer.

  12. Hydrogen-burn survival: preliminary thermal model and test results

    Energy Technology Data Exchange (ETDEWEB)

    McCulloch, W.H.; Ratzel, A.C.; Kempka, S.N.; Furgal, D.T.; Aragon, J.J.

    1982-08-01

    This report documents preliminary Hydrogen Burn Survival (HBS) Program experimental and analytical work conducted through February 1982. The effects of hydrogen deflagrations on safety-related equipment in nuclear power plant containment buildings are considered. Preliminary results from hydrogen deflagration experiments in the Sandia Variable Geometry Experimental System (VGES) are presented and analytical predictions for these tests are compared and discussed. Analytical estimates of component thermal responses to hydrogen deflagrations in the upper and lower compartments of an ice condenser, pressurized water reactor are also presented.

  13. Hydrogen-burn survival: preliminary thermal model and test results

    International Nuclear Information System (INIS)

    This report documents preliminary Hydrogen Burn Survival (HBS) Program experimental and analytical work conducted through February 1982. The effects of hydrogen deflagrations on safety-related equipment in nuclear power plant containment buildings are considered. Preliminary results from hydrogen deflagration experiments in the Sandia Variable Geometry Experimental System (VGES) are presented and analytical predictions for these tests are compared and discussed. Analytical estimates of component thermal responses to hydrogen deflagrations in the upper and lower compartments of an ice condenser, pressurized water reactor are also presented

  14. The 2dF Galaxy Redshift Survey: Preliminary Results

    OpenAIRE

    Maddox, S.

    1997-01-01

    Spectroscopic observations for a new survey of 250 000 galaxy redshifts are underway, using the 2dF instrument at the AAT. The input galaxy catalogue and commissioning data are described. The first result from the preliminary data is a new estimate of the galaxy luminosity function at =0.1.

  15. Preliminary results of neutron production in Sahand plasma focus device

    International Nuclear Information System (INIS)

    We report in this paper the preliminary results of neutron generation during fusion reaction in deuterium in the Sahand Filipov type plasma focus, recently installed and put in operation at Tabriz University. The special calibration procedure for neutron detection system, using activation method is described

  16. On the quadratic stability of switched interval systems: Preliminary results

    OpenAIRE

    Zeheb, Ezra; Mason, Oliver; SOLMAZ, Selim; Shorten, Robert

    2005-01-01

    In this paper we present some preliminary results on the quadratic stability of switched systems with uncertain parameters. We show that the quadratic stability of a class of switched uncertain systems may be readily verified using simple algebraic conditions. Examples are presented to demonstrate the efficacy of our techniques.

  17. Structural investigations of biogenic iron oxide samples. Preliminary results

    International Nuclear Information System (INIS)

    Some preliminary results on morphology and structure of iron oxide particles formed inside Klebsiella oxytoca bacteria are presented. In particular, by means of optical microscopy, scanning electron microscopy and small-angle X-ray scattering the effect of the bacteria age (the duration of growth) on the nanoparticles properties is studied

  18. Radon concentrations in Norwegian kindergartens: survey planning and preliminary results

    International Nuclear Information System (INIS)

    An extensive radon survey in Norwegian kindergartens and schools was started in early 1997; so far 2481 kindergartens were examined. Preliminary results of the first phase of the survey are presented in tabular and graphic form including, among others, the dependence of average radon concentration on the construction year of the kindergartens and on the age of the buildings. (A.K.)

  19. Preliminary results of the surveillance extension program of NPP Paks

    International Nuclear Information System (INIS)

    The paper describes the preliminary stage of the surveillance extension programme at NPP Paks. To prepare the surveillance extension programme 5 set of specimens including 6 different forging and weldment have been irradiated and tested. The obtained results are used in the final design of the extended surveillance programme of NPP Paks. (author). 3 refs, 6 figs, 1 tab

  20. The friction of polymers around Tg,Tm : Preliminary results

    DEFF Research Database (Denmark)

    Sivebæk, Ion Marius; Samoilov, V N; Persson, B N J

    We present Molecular Dynamics calculations involving polymers of different lengths. Polymers with lengths from 20 to 1400 carbon atoms are considered. The systems are able to simulate friction between polymer surfaces and polymer against metal. The results we present are very preliminary and they...

  1. The activity of energy-providing enzymes of Guerin's carcinoma transplanted under a preliminary low-dose irradiation

    International Nuclear Information System (INIS)

    The intensity of mitochondria swelling and the H+-ATP-ase and succinate dehydrogenase activities are studied in the dynamics of Guerin's carcinoma growth under condition of preliminary low-dose irradiation. The increase of Guerin's carcinoma mitochondria swelling with a maximum at terminal stages with a tendency of inhibition of the H+-ATP-ase and succinate dehydrogenase activities is determined. Low-dose preliminary irradiation caused an increase of high amplitude mitochondria swelling and a decrease of studied activities of mitochondria membrane-associated enzymes at the latent stage of oncogenesis as compared with those in unirradiated rats with tumor.

  2. Hellenic Amateur Astronomy Association's activities: Preliminary results on Perseids 2010

    Science.gov (United States)

    Maravelias, G.

    2011-01-01

    Preliminary results on the Perseids 2010 are presented. Visual and video observations were obtained by the author and a first reduction of the visual data shows that a maximum of ZHR ~120 was reached during the night 12-13 of August 2010. Moreover, a video setup was tested (DMK camera and UFO Capture v2) and the results show that, under some limitations, valuable data can be obtained.

  3. Ethmoid sinus carcinomas: natural history and treatment results

    International Nuclear Information System (INIS)

    Purpose: This retrospective study was undertaken to assess the clinical features and results of treatment of carcinomas of the ethmoid sinus. Materials and methods: The records of 34 patients with ethmoid sinus carcinomas treated with curative intent at the U.T.M.D. Anderson Cancer Center (UTMDACC) between January 1969 and December 1993 were reviewed. The age of the patients ranged from 28 to 73 years with a median of 57 years. There were 28 Whites, four Hispanics, one Black and one Asian. A simple staging based on anatomical criteria was used to describe the extent of the disease. Six patients had T1, 13 patients had T2 and 15 patients had T3 disease. Twenty-one patients were treated with surgery plus radiation and 13 patients were treated with radiotherapy alone; nine patients received adjuvant chemotherapy. Radiation was given at ∼2 Gy per fraction to total doses of 50 Gy preoperatively, 52-66 Gy (median 60 Gy) postoperatively and 50-70 Gy (median 63 Gy) when no surgery was performed. Results: The actuarial 5-year overall, disease-free and disease-specific survival rates were 55%, 58% and 63%, respectively. The actuarial 5-year local control rate was 71% for the whole group (74% for surgery plus radiation and 64% for radiation alone). Local recurrence occurred in nine patients, nodal relapse occurred in three patients and distant metastases occurred in four patients. Histologically proven dura mater invasion was associated with a poorer local control rate in patients undergoing surgery and radiation. The simple T-staging system used in this study was a good discriminator for local control. Of nine patients receiving chemotherapy, three had complete responses and four had partial responses; six of the seven responders had undifferentiated carcinoma. Severe complications of therapy occurred in patients treated between 1969 and 1984 and consisted mainly of visual impairment and brain necrosis. Conclusions: This retrospective review of a large single institutional

  4. Uso de mitomicina C tópico no tratamento da neoplasia intra-epitelial córneo-conjuntival e carcinoma espinocelular conjuntival: resultados preliminares Topical use of mitomycin C for the treatment of corneal-conjunctival intraepithelial neoplasia and conjunctival squamous cell carcinoma: preliminary results

    OpenAIRE

    Priscilla Luppi Ballalai; José Álvaro Pereira Gomes; Myrna Serapião dos Santos; Denise de Freitas; Clélia Maria Erwenne; Moacyr Rigueiro

    2003-01-01

    OBJETIVO: Avaliar a segurança, a eficácia e a recidiva tumoral após o uso de mitomicina C (MMC) tópica no tratamento de neoplasias intra-epiteliais (NIC) primárias e recidivadas e carcinomas espinocelulares (CEC) recidivados. MÉTODOS: Dois grupos de pacientes foram tratados. Grupo 1 com diagnóstico de NIC primário ou recidivado fez uso do colírio de MMC 0,02%, 4 vezes ao dia por 28 dias. O grupo 2 com diagnóstico de CEC recidivado fez uso do colírio de MMC 0,02%, 4 vezes ao dia por 21 a 28 di...

  5. Preliminary Simulation Results of the 23 June, 2001 Peruvian Tsunami

    Science.gov (United States)

    Titov, V. V.; Koshimura, S.; Ortiz, M.; Borrero, J.

    2001-12-01

    The tsunami generated by the June 23, 2001 Peruvian earthquake devastated a 50--km section of coast near the earthquake epicenter and was recorded on tide-gages throughout the Pacific. The coastal town of Camana sustained the most damage with tsunami waves penetrating up to 1--km inland and runup exceeding 5--m. The extreme local effects and widespread impact motivated modeling efforts to produce a realistic tsunami simulation of this event. Preliminary results were produced by the TIME center using two resident numerical models, TUNAMI--2 and MOST. Both models were used to produce preliminary simulations shortly after the earthquake, and first results were posted on the Internet a day after the event (http://www.pmel.noaa.gov/tsunami/peru_pmel.html). These numerical results aimed to quantify the magnitude of the tsunami and, to certain extent, to guide the post-tsunami survey. The first simulations have been revised using new data about the seismic source and the results of the post-tsunami survey. Measured inundation distances, flow depths, and runup along topographic transects are used to constrain the inundation model. Preliminary numerical analysis of tsunami inundation will be presented.

  6. Preliminary Results of the MOSES II 2015 Flight

    Science.gov (United States)

    Smart, Roy; Courrier, Hans; Kankelborg, Charles

    2016-05-01

    The Multi-Order Extreme Ultraviolet Spectrograph (MOSES) is a slitless spectrograph which aims to produce simultaneous spatial-spectral imaging of the solar transition region. This is accomplished through a multilayer concave diffraction grating which produces three images for the spectral orders m = 0, ± 1. The multilayer coating provides a narrow passband, dominated by Ne VII (46.5 nm), which allows the three images to be compared in order to determine line broadenings and identify explosive events in the Solar Transition Region. Here, we examine the preliminary results of MOSES II, the instrument’s second flight which was launched on a sounding rocket from White Sands Missile Range, NM in August 2015. We present the first images of the Sun in Ne VII since Skylab and the preliminary results of observed doppler shifts within an active region.

  7. Preliminary results of the echo-seeding experiment at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, D.; Colby, E.; Ding, Y.; Dunning, M.; Frederico, J.; Gilevich, S.; Hast, C.; Jobe, K.; McCormick, D.; Nelson, J.; Raubenheimer, T.O.; Soong, K.; Stupakov, G.; Szalata, Z.; Walz, D.; Weathersby, S.; Woodley, M.; Corlett, J.; Qiang, J.; Penn, G.; Prestemon, S.; Schlueter, R.; Venturini, M.; Wan, W.; Pernet, P-L.

    2010-05-23

    ECHO-7 is a proof-of-principle echo-enabled harmonic generation FEL experiment in the Next Linear Collider Test Accelerator (NLCTA) at SLAC. The experiment aims to generate coherent radiation at 318 nm and 227 nm, which are the 5th and 7th harmonic of the infrared seed laser. In this paper we present the preliminary results from the commissioning run of the completed experimental setup which started in April 2010.

  8. Intercomparison Of Spectroradiometers For Solar Spectral Irradiance Measurements. Preliminary Results.

    OpenAIRE

    Galleano, Roberto; ZAAIMAN Willem; MORABITO Paolo; Minuto, Alessandro; Spena, Angelo; Bartocci, Simona; Fucci, Raffaele; Leanza, Gianni; PAVANELLO Diego; VIRTUANI Alessandro; FASANARO Daniela; CATENA Mario; NORTON Matthew

    2011-01-01

    This paper describes the preliminary results of an intercomparison of spectroradiometers for direct (DNI) and global normal incidence (GNI) irradiance in the visible (VIS) and near infrared (NIR) region. Seven institutions and six spectroradiometers, representing different technologies and manufacturers were involved. All instruments were able to measure GNI; a restricted sub-group of four instruments had the possibility to also measure DNI when equipped with proper collimators. P...

  9. 9.4T Human MRI: Preliminary Results

    OpenAIRE

    VAUGHAN, THOMAS; DelaBarre, Lance; Snyder, Carl; Tian, Jinfeng; Akgun, Can; Shrivastava, Devashish; Liu, Wanzahn; Olson, Chris; Adriany, Gregor; Strupp, John; Andersen, Peter; Gopinath, Anand; Van de Moortele, Pierre-Francois; Garwood, Michael; Ugurbil, Kamil

    2006-01-01

    This work reports the preliminary results of the first human images at the new high-field benchmark of 9.4T. A 65-cm-diameter bore magnet was used together with an asymmetric 40-cm-diameter head gradient and shim set. A multichannel transmission line (transverse electromagnetic (TEM)) head coil was driven by a programmable parallel transceiver to control the relative phase and magnitude of each channel independently. These new RF field control methods facilitated compensation for RF artifacts...

  10. Preliminary Results of Lunar Topography by KAGUYA-LALT Mission

    Science.gov (United States)

    Araki, Hiroshi; Tazawa, Seiichi; Noda, Hirotomo; Migita, Emiko; Kamiya, Izumi; Kawano, Nobuyuki; Sasaki, Sho

    The Laser Altimeter (LALT) on board the main orbiter of KAGUYA (SELENE) started nominal observation on December 30, 2007 for mapping the lunar topography. As of March 31, 2008, LALT has obtained about 6.7 million topographic data and the return rate is 97%. Several qualifications of the data to produce reliable topography are now in progress. The present status and preliminary results are reported in this article.

  11. Preliminary results of Digital Pulse Shape Acquisition from Chimera

    Energy Technology Data Exchange (ETDEWEB)

    Alderighi, D.M.; Sechi, G. [INFN Milano and IASF, CNR, Milano (France); Anzalone, A.; Cavallaro, S.; Giustolisi, F.; Laguidara, E.; Lanzalone, G.; Porto, F. [Catania Univ., LNS and Dipartimento di Fisica (France); Bassini, R.; Boiano, C.; Guazzoni, P.; Russo, S.; Sassi, M.; Zetta, L. [Milano Univ., INFN and Dipartimento di Fisica (Italy); Cardella, G.; Defilippo, S.E.; Lanzano, G.; Paganod, A.; Papa, M.; Pirrone, S.; Politi, G. [Catania Univ., INFN and Dipartimento di Fisica (Italy); Geraci, E. [Bologna Univ., INFN and Dipartimento di Fisica (Italy)

    2003-07-01

    A 100 MS/s 14-bit Sampling Analog-to-Digital converter has been used to perform digital pulse-shape acquisition of signals collected from CHIMERA telescopes. The signals from a typical CHIMERA detection cell have been collected using both a standard CHIMERA electronic chain up to the amplifier, and a very simple analog front end, basically reduced to the preamplifier. The preliminary on-beam results are presented. (authors)

  12. Preliminary results of Digital Pulse Shape Acquisition from Chimera

    International Nuclear Information System (INIS)

    A 100 MS/s 14-bit Sampling Analog-to-Digital converter has been used to perform digital pulse-shape acquisition of signals collected from CHIMERA telescopes. The signals from a typical CHIMERA detection cell have been collected using both a standard CHIMERA electronic chain up to the amplifier, and a very simple analog front end, basically reduced to the preamplifier. The preliminary on-beam results are presented. (authors)

  13. Preliminary result of Indonesian strain map based on geodetic measurements

    Science.gov (United States)

    Susilo, Meilano, Irwan; Abidin, Hasanuddin Z.; Sapiie, Benyamin; Efendi, Joni; Wijanarto, Antonius B.

    2016-05-01

    GPS measurements from 1993 until 2014 across Indonesia region are providing longer time series at 2 - 3 millimetre-level precision from which surface velocity estimates are derived. In this study, we use this GPS velocities field to construct a crustal strain rate map and not including the physical model yet. In our preliminary result, we only compute the magnitude of the strain rate. The strain map is useful to construct the deformation model in Indonesia and to support the Indonesia datum.

  14. Rad51 Expression in Nasopharyngeal Carcinoma and Its Association with Tumor Reduction: A Preliminary Study in Indonesia

    Science.gov (United States)

    Cahyanti, Dian; Rachmadi, Lisnawati; Wulani, Vally; Adham, Marlinda

    2016-01-01

    Background: Overexpression of Rad51 protein in many tumor cells has been proven to increase radioresistance and can be related to the resistance of chemosensitivity of tumor cells. This preliminary study was conducted to determine the relationship between the Rad51 expression level in nasopharyngeal carcinoma and the response of the treatment based on the measurement of the tumor reduction. Methods: Thirteen cases of the NPCs were analyzed. The expression levels of the Rad51 were examined from the pretreatment biopsies. Furthermore, tumor reductions were determined based on the change in sum longest diameter of the nasopharyngeal CT-scan before and after therapy. Results: The expression level of the Rad51 was associated with the reduction of tumor mass. The P value was 0.049 and the correlation coefficient was 0.479. Conclusion: The tumor cells Rad51 expression levels may affect the tumor reduction of NPC after the therapy.

  15. Treatment results of pediatric nasopharyngeal carcinoma, NCI, Cairo University experience

    International Nuclear Information System (INIS)

    Investigate treatment outcome, prognostic factors and survival among selected group of Egyptian pediatric nasopharyngeal carcinoma patients. Patients and methods Thirty patients treated from non-metastatic nasopharyngeal carcinoma between 1997 and 2012 were retrospectively evaluated including: TNM staging, chemo-radiotherapy regimens. Survival analysis was done using Kaplan–Meier survival curves. Results Twenty-three males and 7 females (M:F 3.2:1) with median age of 14 years; 84% with stages III/IV. Neck node enlargement was reported in 90% (27/30). Induction chemotherapy followed by radiotherapy was implemented in 80% of patients. Mucositis (87%) was the commonest treatment related toxicity. Nineteen patients (63%) were in CR with a median FU of 69 months (range 24–160). Eleven patients had treatment local and distant failures (2 local, 7 distant and 2 local/distant) at a median FU of 24 and 34 months respectively. 5-year overall and event-free survival rates were 77% and 63% respectively. Prolonged OAP of RT ⩾ 50 days, Hb<11 g% and T4 stage affected EFS and OAS on UVA; while on MVA; prolonged OAP of RT ⩾ 50 days (ρ = 0.002) and T4 stage (ρ = 0.004) affected EFS and only Hb < 11 g% (ρ = 0.019) affected OAS. Late toxicity was reported in 70% of irradiated patients. Conclusion Radio-chemotherapy management for pediatric NPC resulted in comparable treatment outcomes with tolerable late effects. Response adapted radio-chemotherapy regimens in addition to the potential use of IMRT should be recommended to decrease treatment related side effects. Prolonged OAP of RT ⩾ 50 days and low Hb level were encountered as adverse prognostic factors; findings that need further investigation.

  16. I Might Have Some Bad News: Disclosing Preliminary Pathology Results.

    Science.gov (United States)

    Roh, Michael H; Shuman, Andrew G

    2016-01-01

    Cytopathology is a subspecialty of pathology in which pathologists frequently interact directly with patients. Often this interaction is in the context of fine needle aspiration (FNA) procedures performed at the bedside by the cytopathologist or by another clinician with the cytopathologist present. Patient requests for preliminary results in such settings raise fundamental questions about professional scope of practice and communication of uncertainty that apply not merely to pathologists but to all clinicians. In certain settings, cytopathologists may share preliminary diagnostic impressions directly with patients. Essential to these conversations is the need to articulate potential uncertainty about both the diagnosis and next steps. In addition, the involvement and notification of the referring physician is obligatory, both for care coordination and to ensure that patients receive a consistent message. PMID:27550561

  17. Preliminary Results on Uncertainty Quantification for Pattern Analytics

    Energy Technology Data Exchange (ETDEWEB)

    Stracuzzi, David John [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Brost, Randolph [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Chen, Maximillian Gene [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Malinas, Rebecca [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Peterson, Matthew Gregor [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Phillips, Cynthia A. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Robinson, David G. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Woodbridge, Diane [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    This report summarizes preliminary research into uncertainty quantification for pattern ana- lytics within the context of the Pattern Analytics to Support High-Performance Exploitation and Reasoning (PANTHER) project. The primary focus of PANTHER was to make large quantities of remote sensing data searchable by analysts. The work described in this re- port adds nuance to both the initial data preparation steps and the search process. Search queries are transformed from does the specified pattern exist in the data? to how certain is the system that the returned results match the query? We show example results for both data processing and search, and discuss a number of possible improvements for each.

  18. The role of apparent diffusion coefficient values in detecting testicular intraepithelial neoplasia: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Tsili, Athina C., E-mail: a_tsili@yahoo.gr [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Ntorkou, Alexandra, E-mail: alexdorkou@yahoo.com [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Baltogiannis, Dimitrios, E-mail: Greece.dbaltog@cc.uoi.gr [Department of Urology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Goussia, Anna, E-mail: agoussia@uoi.gr [Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Astrakas, Loukas G., E-mail: astrakas@uoi.gr [Department of Medical Physics, Medical School, University of Ioannina, 45110 Ioannina (Greece); Malamou-Mitsi, Vasiliki, E-mail: vmalamou@cc.uoi.gr [Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Sofikitis, Nikolaos, E-mail: akrosnin@hotmail.com [Department of Urology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Argyropoulou, Maria I., E-mail: margyrop@cc.uoi.gr [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece)

    2015-05-15

    Highlights: • ADC values proved useful in the discrimination between TGCNs and normal testis. • Testicular intraepithelial neoplasia represents the precursor of most TGCNs. • ADC values cannot be used to detect testicular intraepithelial neoplasia. - Abstract: Introduction: The aim of this study is to improve detection of testicular intraepithelial neoplasia (TIN) by measurement of apparent diffusion coefficient (ADC) values. Materials and methods: Fifty-six MRI examinations of the scrotum, including 26 histologically proven testicular germ cell neoplasms were retrospectively evaluated. DWI was performed using a single shot, multi-slice spin-echo planar diffusion pulse sequence and b-values of 0 and 900 s mm{sup −2}. ADC measurements were classified into three groups according to their location: group 1 (n = 19), non-tumoral part, adjacent to testicular carcinoma, where the possible location of TIN was; group 2 (n = 26), testicular carcinoma; and group 3 (n = 60), normal testicular parenchyma. Analysis of variance (ANOVA) followed by post hoc analysis (Dunnett T3) was used for statistical purposes. Results: The mean ± s.d. of ADC values (×10{sup −3} mm{sup 2}/s) of different groups were: group 1, 1.08 ± 0.20; group 2, 0.72 ± 0.27; and group 3, 1.11 ± 0.14. ANOVA revealed differences of mean ADC between groups (F = 38.859, P < 0.001). Post hoc analysis showed differences between groups 2 and 3 (P < 0.001), groups 2 and 1 (P < 0.001), but not between groups 3 and 1 (P = 0.87). Conclusions: Based on our preliminary results, ADC values do not provide a reliable differentiation between TIN and testicular carcinoma or normal testicular parenchyma.

  19. The role of apparent diffusion coefficient values in detecting testicular intraepithelial neoplasia: Preliminary results

    International Nuclear Information System (INIS)

    Highlights: • ADC values proved useful in the discrimination between TGCNs and normal testis. • Testicular intraepithelial neoplasia represents the precursor of most TGCNs. • ADC values cannot be used to detect testicular intraepithelial neoplasia. - Abstract: Introduction: The aim of this study is to improve detection of testicular intraepithelial neoplasia (TIN) by measurement of apparent diffusion coefficient (ADC) values. Materials and methods: Fifty-six MRI examinations of the scrotum, including 26 histologically proven testicular germ cell neoplasms were retrospectively evaluated. DWI was performed using a single shot, multi-slice spin-echo planar diffusion pulse sequence and b-values of 0 and 900 s mm−2. ADC measurements were classified into three groups according to their location: group 1 (n = 19), non-tumoral part, adjacent to testicular carcinoma, where the possible location of TIN was; group 2 (n = 26), testicular carcinoma; and group 3 (n = 60), normal testicular parenchyma. Analysis of variance (ANOVA) followed by post hoc analysis (Dunnett T3) was used for statistical purposes. Results: The mean ± s.d. of ADC values (×10−3 mm2/s) of different groups were: group 1, 1.08 ± 0.20; group 2, 0.72 ± 0.27; and group 3, 1.11 ± 0.14. ANOVA revealed differences of mean ADC between groups (F = 38.859, P < 0.001). Post hoc analysis showed differences between groups 2 and 3 (P < 0.001), groups 2 and 1 (P < 0.001), but not between groups 3 and 1 (P = 0.87). Conclusions: Based on our preliminary results, ADC values do not provide a reliable differentiation between TIN and testicular carcinoma or normal testicular parenchyma

  20. Preliminary Neutronics Results for the OECD MHTGR-350 Benchmark

    International Nuclear Information System (INIS)

    The benchmark problem is based on the MHTGR-350 reactor designed by General Atomics (GA). Phase I of the problem has three steady state exercises : Exercise 1 for neutronics stand alone with fixed cross-sections, Exercise 2 for thermal-fluids stand alone and Exercise 3 for coupled steady state. Phase II is defined for coupled transient cases. Phase III is defined to test the depletion capabilities of lattice physics codes. Phase III has two exercises : Exercise 1 for cold state and Exercise 2 for hot state. In this paper, a preliminary results for Exercise 1 of Phase I obtained by using CAPP code and the results for Phase III by McCARD code are presented. In this paper, some preliminary neutronics results for the OECD/NEA MHTGR-350 neutronics/thermal fluids coupled benchmark problem were presented and some of the global parameters for Phase I Exercise 1 were compared with those presented by INL research group. They showed a good agreement with each other. The results for Phase III were also reasonable. The benchmark is ongoing and more comparisons with the results of other research groups will be made as soon as they are available

  1. Preliminary results on Niobium sputtered films inside TESLA type cavities

    International Nuclear Information System (INIS)

    In the framework of the ARES project and as a possible application for TESLA we realized a test set-up to study the deposition of Nb films inside a single-cell TESLA type cavity. The plasma confinement was obtained with two external coils centered on the cavity axis in a magnetic bottle configuration. The system is operational and optimization of the discharge parameters is in progress: samples are produced to test the film quality. This paper covers a brief description of the test set-up and preliminary results on samples (thickness, RRR, and XRD measurements). (author)

  2. Escherichia coli O26 IN RAW BUFFALO MILK: PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    A. Rella

    2013-02-01

    Full Text Available Escherichia coli O26 is considered to be one of the most important food-borne pathogen. In this study, 120 buffalo milk samples collected in Lazio and in Apulia regions were tested for the presence of E. coli O26. One buffalo milk sample (0,8% tested positive for E. coli O26; the isolate was positive at the verocytotoxicity test and it showed resistance properties to different antimicrobial classes. These preliminary results highlight the need to monitor the foods of animal origin used for production and eaten by a wide range of persons, respect VTEC organism.

  3. Ruptured Achilles tendon--preliminary results of a new treatment.

    OpenAIRE

    Cetti, R.

    1988-01-01

    The preliminary results of a new treatment of ruptured Achilles tendons are presented. The new treatment consists of a new tendon suture and a new post-operative cast in which it is possible to make non-weight bearing movements of the ankle immediately after the operation. This makes it possible to walk the day after the operation, causes very little discomfort during the time in a cast, gives a quick return to normal mobility with normal plantar flexion strength and makes it possible to resu...

  4. V and V Efforts of Auroral Precipitation Models: Preliminary Results

    Science.gov (United States)

    Zheng, Yihua; Kuznetsova, Masha; Rastaetter, Lutz; Hesse, Michael

    2011-01-01

    Auroral precipitation models have been valuable both in terms of space weather applications and space science research. Yet very limited testing has been performed regarding model performance. A variety of auroral models are available, including empirical models that are parameterized by geomagnetic indices or upstream solar wind conditions, now casting models that are based on satellite observations, or those derived from physics-based, coupled global models. In this presentation, we will show our preliminary results regarding V&V efforts of some of the models.

  5. Clinical results of salvage surgery in hypopharynx carcinoma after chemoradiotherapy

    International Nuclear Information System (INIS)

    The incidence of post-operative complications and treatment results of 60 cases of hypopharynx carcinoma receiving laryngo-pharyngo-esophagectomy followed by reconstruction with jejunum after chemoradiotherapy (CRT) from 1997 to 2006 in 6 hospitals was analyzed. The overall complication rate was 57%. There were 3 cases with carotid artery rupture (5%), 4 with jejunum necrosis (6%), 6 with major salivary fistula (10%), 8 with minor salivary fistula (13%), 8 with abscess alone (13%), 3 with trachea stoma necrosis (5%), and 3 with skin flap necrosis (5%). The death rate due to surgical complications was 3% (2/60). When the cases were divided into two groups, namely the cases with fistula and the cases without fistula, the number of days that permitted drinking was 18.1 in the latter and 81.8 in the former. The 5-year overall survival rate among all cases was 37%. We found that salvage surgery after CRT was effective for recurrent cases. These findings suggest that reconstruction with jejunum is a suitable type of operation with better surgical results. Care is required to reduce the incidence of post-operative complications. (author)

  6. Preliminary Results Of A 600 Joules Small Plasma Focus Device

    Science.gov (United States)

    Lee, S. H.; Yap, S. L.; Wong, C. S.

    2009-07-01

    Preliminary results of a 600 J (3.7 μF, 18 kV) Mather type plasma focus device operated at low pressure will be presented. The discharge is formed between a solid anode with length of 6 cm and six symmetrically and coaxially arranged cathode rods of same lengths. The cathode base is profiled in a knife-edge design and a set of coaxial plasma gun are attached to it in order to initiate the breakdown and enhance the current sheath formation. The experiments have been performed in argon gas under a low pressure condition of several microbars. The discharge current and the voltage across the electrodes during the discharge are measured with high voltage probe and current coil. The current and voltage characteristics are used to determine the possible range of operating pressure that gives good focusing action. At a narrow pressure regime of 9.0±0.5 μbar, focusing action is observed with good reproducibility. Preliminary result of ion beam energy is presented. More work will be carried out to investigate the radiation output.

  7. Transarterial Chemoembolization (TACE) in hepatocellular carcinoma: Technique, indication and results

    International Nuclear Information System (INIS)

    To present current data on technique, indications and results of transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). The principle of TACE is the intra-arterial injection of chemotherapeutic drug combinations like doxorubicin, cisplatin and mitomycin into the hepatic artery, followed by lipiodol injection, Gelfoam for vessel occlusion and degradable microspheres. The side effects and complications after TACE range from fever, upper abdominal pain and vomiting to acute or chronic liver cell failure. The palliative effect in unresectable HCC using TACE allows local tumor control in 15 to 60% of cases and 5-year survival rates ranging from 8 - 43%. The potentially curative treatment option allows local tumor control from 18 - 63%. The neoadjuvant treatment option of TACE in combination with other treatment options like percutaneous ethanol injection (PEI) or radiofrequency ablation (RFA) reach local tumor control rates between 80 - 96%. The bridging effect of TACE before liver transplantation reaches 5-year survival rates from 59 - 93%. The symptomatic therapy option of TACE is used to counteract pain directly caused by HCC and acute/subacute bleeding in the HCC. The local tumor response reaches up to 88% and the bleeding control is from 83 to 100%. (orig.)

  8. Results of combined therapy for maxillary sinus squamous cell carcinoma

    International Nuclear Information System (INIS)

    The results of 54 cases of maxillary sinus squamous cell carcinoma treated between 1980 and 2002 were analyzed retrospectively. The T classification according to the 1997 Union Internationale Contre le Cancer (UICC) was as follows: 2 with stage T1, 29 with T3, and 23 with T4. Ten patients (18.5 %) had lymph node metastases at diagnosis. All patients underwent combined therapy including radiotherapy, surgery, and regional or systemic chemotherapy. Fifteen patients received hyperfractionated twice-daily radiotherapy (1.2 Gy or 1.5 Gy/fraction), and the remaining 39 patients received a conventional once-daily regimen (1.5-2 Gy/fraction). The 5-year overall survival and 5-year disease-free survival for all patients were 56.0% and 46.7%, respectively. The N classification was the only significant prognostic factor for 5-year disease-free survival by univariate analysis (favoring N=0, p=0.04). There were no significant differences in other prognostic factors including gender, T classification (T1-3 vs. T4), hyperfractionated radiotherapy (yes vs. no), total dose (biological effective dose (BED): 10 vs. ≥69 Gy10), and intra-arterial chemotherapy (yes vs. no). Although radiation-induced cataract was observed in 9 patients, no other severe late complications developed. (author)

  9. MR angiography of the abdominal aorta: Preliminary results

    International Nuclear Information System (INIS)

    Flowing blood can be demonstrated as bright signal in MR-imaging resulting in MR-angiography (MRA). This study presents the results of MRA using the 'time of flight'-effect in which projection angiograms along the longitudinal axis were established by a row of 2D-gradient echo (GE) images (FLASH) in breathhold technique. The method was proven in 5 normal volunteers and evaluated against DSA in 21 patients with aortic diseases. The preliminary results demonstrate a satisfactory flow signal in the normally perfused aorta; thus occlusions, stenoses, and aneurysms could be defined clearly. In smaller vessels the signal was still insufficient. Diagnostic problems of vascular overlapping can be solved in most cases by rotating the angiograms, and by additional analysis of individual 2D-GE images. In the present form the quality of MRA is still inferior to that of DSA. (orig.)

  10. Preliminary Results Of LOCA Problem For APR1400 Reactor

    International Nuclear Information System (INIS)

    Several features of NPP with APR1400 nuclear reactor during a loss of coolant accident (LOCA) are investigated in this study. The report describes some main design characteristics of an engineering safety systems of APR1400 and the thermal hydraulic calculation results for steady-state using MARS and RELAP/SCDAPSIM codes. Large Break LOCA accident has been analyzed and evaluated based on acceptable criteria for ECCS given by US NRC. The results from cold leg break LOCA with broken area of 0.0465 m2 in case of high pressure safety injection system (HPSI) failed to operate or 2 and 4 HPSI pumps are activated. The preliminary results of this work is a part of collaboration between INST researchers and KAERI experts in using RELAP tool for safety analysis of NPPs. (author)

  11. Implications of Scheduled ITC Reversion for RPS Compliance: Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Lowder, Travis; Miller, John; O' Shaughnessy, Eric; Heeter, Jenny

    2015-09-14

    This poster presents DRAFT initial results of a forthcoming NREL analysis. The analysis investigates the impacts of the scheduled investment tax credit (ITC) reversion from 30 percent to 10 percent for certain solar photovoltaic projects. Specifically, it considers whether the reversion will result in increased use of alternative compliance payments (ACPs) in lieu of solar renewable energy credits (SRECs) for renewable portfolio standard (RPS) compliance. The analysis models the effect of a 10 percent ITC on power purchase agreement (PPA) prices for non-residential systems in the eight states with solar carve-outs and solar ACPs. Our preliminary results suggest that states will likely install sufficient capacity to meet long-term targets through SRECs rather than ACPs following the ITC reversion. However, the analysis shows that the ITC reversion could affect project economics such that capacity shortfalls in certain states could temporarily increase the use of ACPs. NREL anticipates publishing a full report of this analysis in fall 2015. credits (SRECs) for renewable portfolio standard (RPS) compliance. The analysis models the effect of a 10 percent ITC on power purchase agreement (PPA) prices for non-residential systems in the eight states with solar carve-outs and solar ACPs. Our preliminary results suggest that states will likely install sufficient capacity to meet long-term targets through SRECs rather than ACPs following the ITC reversion. However, the analysis shows that the ITC reversion could affect project economics such that capacity shortfalls in certain states could temporarily increase the use of ACPs. NREL anticipates publishing a full report of this analysis in fall 2015.

  12. Comparison of Treatment Results Between Adult and Juvenile Nasopharyngeal Carcinoma

    International Nuclear Information System (INIS)

    Purpose: Nasopharyngeal carcinoma (NPC) has a bimodal age distribution. In contrast to the adult variant, little is known about the juvenile form. This study examined the treatment results between adult (aNPC) and juvenile NPC (jNPC) patients for future treatment considerations in jNPC. Methods and Materials: The jNPC population included 53 patients treated at two institutions between 1972 and 2004. The aNPC population included 84 patients treated at one institution. The patients had received a median dose of 66 Gy of external beam radiotherapy and 72% underwent chemotherapy. The mean follow-up for surviving patients was 12.6 years for jNPC and 6.6 years for aNPC. Results: The jNPC patients presented with more advance stages than did the aNPC patients (92% vs. 67% Stage III-IV, p = .006). However, jNPC patients had significantly better overall survival (OS) than did aNPC patients. The 5-year OS rate was 71% for jNPC and 58% for aNPC (p = .03). The jNPC group also demonstrated a trend for greater relapse-free survival than the aNPC group (5-year relapse-free survival rate, 69% vs. 49%; p = .056). The pattern of failure analysis revealed that the jNPC patients had greater locoregional control and freedom from metastasis but the differences were not statistically significant. Univariate analysis for OS revealed that age group, nodal classification, and chemotherapy use were significant prognostic factors. Age group remained significant for OS on multivariate analysis, after adjusting for N classification and treatment. Conclusion: Despite more advance stage at presentation, jNPC patients had better survival than did aNPC patients. Future treatment strategies should take into consideration the long-term complications in these young patients.

  13. Favourable results of Mohs micrographic surgery for basal cell carcinoma

    DEFF Research Database (Denmark)

    Gniadecki, Robert; Glud, Martin; Mortensen, Kia;

    2015-01-01

    INTRODUCTION: Basal cell carcinoma (BCC) is the most common malignant neoplasm with an annual incidence approaching 200/100,000 person-years. Mohs micrographic surgery (MMS) is widely used in North America and in Europe for treatment of BCC. This technique ensures radical tumour removal, sparing of...

  14. Preliminary results on epidemiology of Coconut Lethal Yellowing in Ghana

    Directory of Open Access Journals (Sweden)

    Bonnot François

    2009-03-01

    Full Text Available Epidemiological studies are of major importance in understanding the determinants of plant diseases in order to control the risks of their spreading. A research programme on the epidemiology of coconut lethal yellowing, or Cape Saint Paul Wilt Disease (CSPWD, in Ghana was launched in March 2007. The objective was to characterize the distribution and spread of the disease in space and time at various scales, and their relation with the environment. This article presents the general strategy used to evaluate the incidence of CSPWD along with the environmental, ecological and agronomical variables at regional level. A survey was undertaken on 1,166 plots of Coconut Sector Development Project (CSDP planted with Malayan Yellow Dwarf (MYD × Vanuatu Tall (VTT hybrids in Western Region and Central Region. Preliminary results on the distribution of CSPWD and outside variables at regional scale, along with their relations, are given.

  15. Ex vivo accommodation simulator II: concept and preliminary results

    Science.gov (United States)

    Ehrmann, Klaus; Ho, Arthur; Parel, Jean-Marie

    2004-07-01

    A new instrument was developed to simulate the accommodation of excised human and animal crystalline lenses. The sclera is attached to 8 radially arranged translation stages and dissected into 8 segments. Change in accommodation is simulated by pulling and releasing the scleral segments, varying the load on the zonules and the capsular bag. Each translation stage is equipped with a sensitive force transducer for simultaneous recording of load and displacement. Additionally, changes in optical power, lens diameter, lens thickness and lens shape can be observed and quantified while the lens is stretched and released. The sensitivity and accuracy of the instrument was verified using steel springs and elastic bands. Preliminary results from sensitivity testing and instrument calibration are presented.

  16. Whole-body imaging at 7T: preliminary results.

    Science.gov (United States)

    Vaughan, J Thomas; Snyder, Carl J; DelaBarre, Lance J; Bolan, Patrick J; Tian, Jinfeng; Bolinger, Lizann; Adriany, Gregor; Andersen, Peter; Strupp, John; Ugurbil, Kamil

    2009-01-01

    The objective of this study was to investigate the feasibility of whole-body imaging at 7T. To achieve this objective, new technology and methods were developed. Radio frequency (RF) field distribution and specific absorption rate (SAR) were first explored through numerical modeling. A body coil was then designed and built. Multichannel transmit and receive coils were also developed and implemented. With this new technology in hand, an imaging survey of the "landscape" of the human body at 7T was conducted. Cardiac imaging at 7T appeared to be possible. The potential for breast imaging and spectroscopy was demonstrated. Preliminary results of the first human body imaging at 7T suggest both promise and directions for further development. PMID:19097214

  17. Preliminary results from LADEE's Neutral Mass Spectrometer (NMS)

    Science.gov (United States)

    Benna, Mehdi; Mahaffy, Paul; Hodges, Richard

    2014-05-01

    The Neutral Mass Spectrometer (NMS) of the Lunar Atmosphere and Dust Environment Explorer (LADEE) Mission is a high sensitivity quadrupole mass spectrometer designed to measure the composition and variability of the tenuous lunar atmosphere. The instrument has been observing the lunar exosphere since 10/17/2013, initially from a near circular 250 km altitude orbit and since 11/11/2013 from an elliptical orbit that reaches to 30-60 km altitude near the sunrise terminator. During its first four months in orbit, the NMS instrument successfully detected exospheric helium, argon and neon and mapped their spatial and temporal variability. Furthermore, the NMS instrument was able to establish new upper limits for many other exospheric species either sputtered or thermally evolved from the lunar surface. This talk will summarize these preliminary results from the NMS measurements.

  18. Preliminary Test Results for the MICE Spectrometer Superconducting Solenoids

    Energy Technology Data Exchange (ETDEWEB)

    Virostek, Steve P.; Green, Michael A; Li, Derun; Zisman, Michael S.; Wang, S.T.; Wahrer, R.; Taylor, Clyde; Lu, X.; Chen, J. Y.; Wang, Mimi; Juang, Tiki

    2008-08-02

    This report describes the MICE spectrometer solenoids as built. Each magnet consists of five superconducting coils. Two coils are used to tune the beam going from or to the MICE spectrometer from the rest of the MICE cooling channel. Three spectrometer coils (two end coils and a long center coil) are used to create a uniform 4 T field (to {+-}0.3 percent) over a length of 1.0 m within a diameter of 0.3 m. The three-coil spectrometer set is connected in series. The two end coils use small power supplies to tune the uniform field region where the scintillating fiber tracker is located. This paper will present the results of the preliminary testing of the first spectrometer solenoid.

  19. Preliminary Test Results for the MICE Spectrometer Superconducting Solenoids

    International Nuclear Information System (INIS)

    This report describes the MICE spectrometer solenoids as built. Each magnet consists of five superconducting coils. Two coils are used to tune the beam going from or to the MICE spectrometer from the rest of the MICE cooling channel. Three spectrometer coils (two end coils and a long center coil) are used to create a uniform 4 T field (to ±0.3 percent) over a length of 1.0 m within a diameter of 0.3 m. The three-coil spectrometer set is connected in series. The two end coils use small power supplies to tune the uniform field region where the scintillating fiber tracker is located. This paper will present the results of the preliminary testing of the first spectrometer solenoid

  20. Preliminary Results of the CASCADE Hidden Sector Photon Search

    CERN Document Server

    Woollett, Nathan; Burt, Graeme; Chattopadhyay, Swapan; Dainton, John; Dexter, Amos; Goudket, Phillipe; Jenkins, Michael; Kalliokoski, Matti; Moss, Andrew; Pattalwar, Shrikant; Thakker, Trina; Williams, Peter

    2015-01-01

    Light shining through a wall experiments can be used to make measurements of photon-WISP couplings. The first stage of the CASCADE experiment at the Cockcroft Institute of Accelerator Science and Technology is intended to be a proof-of-principle experiment utilising standard microwave technologies to make a modular, cryogenic HSP detector to take advantage of future high-power superconducting cavity tests. In these proceedings we will be presenting the preliminary results of the CASCADE LSW experiment showing a peak expected exclusion of $1.10 \\times 10^{-8}$ in the mass range from 1.96$\\mu$eV to 5.38$\\mu$eV, exceeding current limits.

  1. Preliminary results of the first paleontologic investigations in Uruguayan Antarctica

    International Nuclear Information System (INIS)

    Preliminary results of the first Uruguayan paleontollogic and biostratigraphical investigations in Antartica are presented. The field work was performed in fildes Peninsula, King George Island, near Uruguayan station Base Cientifica Antarctica Artigas.Some fossiliferous outcrops were geologic and paleontologically analyzed, among them Fossil Hills, situated in the center part of the peninsula, in front of Ardley Island, between the chinese and chilean stations.This hill is composed of fossil bearing piroclastic and epiclastic rocks, assigned to the fossil Hill Fm. Vegetal remains(petrified wood and leaf impronts) were observed and collected in this unit and it is remarkable the presence of Nothofagus sp. and invertebrate trace fossils, Cochlichmus isp and Helminthopsis isp.The depositional environment deduced from the fossil association in lacustrine, under a warm and humid climate.In the same deposits, other investigators have collected aquatic and ratite bird trace fossils. Paleontologic evidence is not contradictory with the Eocene age previously proposed for the studied deposits. (author)

  2. Status of EUROBALL IV and preliminary physics results

    International Nuclear Information System (INIS)

    Complete text of publication follows. The study of nuclear structure at the limits of angular momentum and isospin is only possible with very selective and powerful detection setups. The EUROBALL γ-ray spectrometer and the many associated ancillary detectors have been designed for that purpose. In its fourth phase, EUROBALL includes an inner BGO ball which works, with the Ge detectors and their suppression shields, like a multiplicity filter and a calorimeter and improves the selectivity of the device. EUROBALL IV is in operation at IReS-Strasbourg since june 1999. More than 20 experiments have already been performed with this very efficient instrument and preliminary results of some of them will be presented in this talk. (author)

  3. Contribution to the radiotherapy of collum and corpus carcinoma (Marburg results 1960-1979)

    International Nuclear Information System (INIS)

    The subject of this work is the therapeutic success of radiation therapy, respectively operation, with uterine carcinoma. For the evaluation 938 patients of the Marburg University Radiation Clinic from the years 1960 to 1979 were included. The 5-year survival rate with collum carcinoma was 56.99% (stage I 79.62%, II 57.29%, III 31.13%, IV 5.88%). With patients with corpus carcinoma the 5-year survival rate was 74.27% (stage II 80.79%, I 77.50%, III 57.50%, IV 30.00%). The results of various radiotherapeutic methods ('Duesseldorf method', 'Marburg method') were discussed. With respect to the international results published in 'Annual Report' the Marburg results for the treatment of collum carcinoma (the 5-year survival rates) are at world level, and the successes in the treatment of corpus carcinoma are clearly better. (TRV)

  4. Benchmarking the Integration of WAVEWATCH III Results into HAZUS-MH: Preliminary Results

    Science.gov (United States)

    Berglund, Judith; Holland, Donald; McKellip, Rodney; Sciaudone, Jeff; Vickery, Peter; Wang, Zhanxian; Ying, Ken

    2005-01-01

    The report summarizes the results from the preliminary benchmarking activities associated with the use of WAVEWATCH III (WW3) results in the HAZUS-MH MR1 flood module. Project partner Applied Research Associates (ARA) is integrating the WW3 model into HAZUS. The current version of HAZUS-MH predicts loss estimates from hurricane-related coastal flooding by using values of surge only. Using WW3, wave setup can be included with surge. Loss estimates resulting from the use of surge-only and surge-plus-wave-setup were compared. This benchmarking study is preliminary because the HAZUS-MH MR1 flood module was under development at the time of the study. In addition, WW3 is not scheduled to be fully integrated with HAZUS-MH and available for public release until 2008.

  5. Surgery for recurrent biliary carcinoma: results for 27 recurrent cases

    OpenAIRE

    Noji, Takehiro; Tsuchikawa, Takahiro; Mizota, Tomoko; Okamura, Keisuke; Nakamura, Toru; Tamoto, Eiji; Shichinohe, Toshiaki; Hirano, Satoshi

    2015-01-01

    Background Various chemotherapies have been used as best practice to treat recurrent biliary malignancies. Conversely, relatively few surgeries have been described for recurrent extrahepatic biliary carcinoma (RExBC), so whether surgery for RExBC is feasible has remained unclear. This retrospective study was conducted to evaluate the feasibility of surgery for RExBC. Methods From February 2000 to January 2014, a total of 27 patients, comprising 18 patients with extrahepatic cholangiocarcinoma...

  6. Techniques and results of brachytherapy for carcinoma of the tongue

    International Nuclear Information System (INIS)

    Three hundred and twelve patients with 1987 UICC T1, 2 carcinoma of the tongue, who underwent definitive brachytherapy from November, 1978 to March, 1991 in the Department of Radiology, Kyushu University Hospital, and from January, 1985 to December, 1994 in the Department of Radiotherapy, Kyushu Cancer Center, were reviewed retrospectively. All patients were admitted 15-30 mg Pentazocine and O.25 mg Atropine sulfate as the premedication. Thirty to 60 minutes after, the tip of tongue and the lesion were put under local infiltration anesthesia with 10-20 ml of 1-2% Lidocaine or 1% Procaine HCL. The tongue was pulled out by the thread of the tip. Partial resection or wide excisional biopsy of the tumor was performed to reduce the tumor volume and the radiation volume and also to estimate Jacobson-Yamamoto's grading histologically in the bottom of the tumor. Radium needles or Iridium hair pins were implanted in the lesion following Paterson's method, and left for 3-10 days to the minimum tumor dose of 70 Gy calculated by computer. The secondary neck lymph node metastases rates of the patients with T1 carcinoma of the tongue were 27% and 53% in the Jacobson-Yamamoto grading 1-3 group and 4 group. The rates of the patients with T2 were 28% and 82% in 1-3 group and 4 group. Two year's local control rates of the patients with T1 and T2 carcinoma were 95% and 82%. Two year's late reaction (mandibular bone exposure or refractory ulcer of soft tissue) rates of the patients with T1 and T2 carcinoma were 7% and 12%. (author)

  7. Preliminary on-orbit results of trigger system for DAMPE

    Science.gov (United States)

    Zhang, Yongqiang; Chang, Jin; Guo, Jian hua; Dong, TieKuang; Liu, Yang

    2016-07-01

    The Dark Matter Particle Explorer (DAMPE), Chinese first high energy cosmic ray explorer in space, has been successfully launched at Jiuquan Satellite Launch Center, with the mission of searching dark matter particle. Large energy range for electron/gamma, good energy resolution, and excellent PID ability, make DAMPE to be the most promising detector so far to find the signal of dark matter. DAMPE consists of four sub-detectors: Plastic Scintillation detector, Silicon-Tungsten tracker, BGO calorimeter and Neutron detector. The hit signals generated by the BGO calorimeter and the trigger board (in DAQ) constitute the trigger system of DAMPE, which will generate trigger signals for the four sub-detectors to start data acquisition. The trigger system reduces the trigger rates on orbit from about 1kHz to 70~100Hz, that releases the stress of DAQ transmitting data to ground. In this paper, we will introduce the trigger system of DAMPE, and present some preliminary on-orbit results e.g. trigger efficiency, together with the beam test results at CERN and the simulation results as comparison.

  8. Uranium and thorium recovery in thorianite ore-preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Gaiotte, Joao V.M. [Universidade Federal de Alfenas, Pocos de Caldas, MG (Brazil); Villegas, Raul A.S.; Fukuma, Henrique T., E-mail: rvillegas@cnen.gov.br, E-mail: htfukuma@cnen.gov.br [Comissao Nacional de Energia Nuclear (CNEN), Pocos de Caldas, MG (Brazil). Lab. de Pocos de Caldas

    2011-07-01

    This work presents the preliminary results of the studies aiming to develop a hydrometallurgical process to produce uranium and thorium concentrates from thorianite ore from Amapa State, Brazil. This process comprises two major parts: acid leaching and Th/U recovery using solvent extraction strategies. Thorianite ore has a typical composition of 60 - 70% of thorium, 8 - 10% lead and 7 - 10% uranium. Sulfuric acid leaching operational conditions were defined as follows: acid/ore ratio 7.5 t/t, ore size below 65 mesh (Tyler), 2 hours leaching time and temperature of 100 deg C. Leaching tests results showed that uranium and thorium recovery exceeded 95%, whereas 97% of lead ore content remained in the solid form. Uranium and thorium simultaneous solvent extraction is necessary due to high sulfate concentration in the liquor obtained from leaching, so the Primene JM-T primary anime was used for this extraction step. Aqueous raffinate from extraction containing sulfuric acid was recycled to the leaching step, reducing acid uptake around 60%, to achieve a net sulfuric acid consumption of 3 t/t of ore. Uranium and thorium simultaneous stripping was performed using sodium carbonate solution. In the aqueous stripped it was added sulfuric acid at pH 1.5, followed by a second solvent extraction step using the tertiary amine Alamine 336. The following stripping step was done with a solution of sodium chloride, resulting in a final solution of 23 g L-1 uranium. (author)

  9. Preliminary comparative proteomics study of cervical carcinoma tissues with different sensitivity to concurrent chemoradiotherapy

    International Nuclear Information System (INIS)

    Objective: To investigate the proteomics differences between the high-sensitivity(HS) and the low-sensitivity(LS) groups of cervical carcinoma treated by concurrent chemoradiotherapy, and to confirm the sensitivity associated proteins in intermediate stage and advanced cervical carcinoma. Methods: Fresh carcinoma tissues were collected from 10 untreated cervical carcinoma patients. According to the response to concurrent chemoradiotherapy, the tissues were classified into HS group and LS group. In the first part of our experiment, protein separation was performed using two-dimensional gel electrophoresis (2-DE) with Amersham 18 cm linear pH 3-10 immobilized pH gradient(IPG) strips. The images of the gels were analyzed by PD-quest 7.0 software to find the differentially expressed protein-spots in each group. Then the differentially expressed protein-spots were incised from the gels and digested by trypsin. The peptide mass fingerprintings (PMF) was acquired by matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS). The proteins were identified by data searched in the Mascot-database. Two differentially expressed proteins were assayed by western blot and immunohistochemical methods. Results: Most of the gels were clear and successfully analyzed by PD-quest 7.0 software. Most of the protein-spots concentrated on the area of 20-100 KDa(Mw) and pH4-8. The average number of the protein-spots was 781 ± 74 in HS group and 766 ± 52 in LS group. The match rate was 87.6% between the two groups. Eight proteins highly in HS group but lowly expressed in LS group included hemoglobin subunit beta, caspase-14 precursor, calmodulindike, S100-A9 protein(MRP-14), galectin-7, HSKERC4, keratin 19 and actin. Ten proteins highly in LS group but lowly expression in HS group included anti HBs antibody light-chain Fab, lamin-B1, WARS protein, flavin reductase, glutamate dehydrogenase 1, nuclear matrix protein 238, retinal dehydrogenase 1, AF165172

  10. InRidge program: Preliminary results from the first cruise

    Digital Repository Service at National Institute of Oceanography (India)

    Mukhopadhyay, R.; Murthy, K.S.R.; Iyer, S.D.; Rao, M.M.M.; Banerjee, R.; Subrahmanyam, A.S.; Shirodkar, P.V.; Ghose, I.

    thicknesses and fresh basaltic nuclei. Preliminary studies indicate a possible mixed hydrothermal and hydrogenous source for these nodules. The water column was also sampled at the Vema and Vityaz transform fault areas....

  11. The Myres Hill remote sensing intercomparison study: preliminary results

    Science.gov (United States)

    Clive, P. J. M.; Chindurza, I.; Ravey, I.; Bass, J.; Boyle, R. J.; Jones, P.; Lang, S. J.; Bradley, S.; Hay, L.; Oldroyd, A.; Stickland, M.

    2008-05-01

    Two remote sensing techniques (SODAR and LIDAR) have been developed for measuring wind speed and turbulence from ground level up to altitudes of 300 m or higher. Although originally developed in the defence sector, these techniques are now generating considerable interest in the renewable energy and meteorological sectors. Despite the benefits of these instruments they are not yet generally accepted for due diligence measurements by wind energy developers and financial institutions. There is a requirement for a series of independent assessments of these new metrology techniques, comparing their measurements with the approved cup-type anemometer readings. This is being addressed at TUV NEL's Myres Hill wind turbine test site in a measurement programme supported by the DIUS National Measurement Systems Measurement for Innovators scheme and a consortium of 21 industrial collaborators. Data from SODAR and LIDAR systems are being compared with results from cup-type anemometers mounted at different heights on an 80m meteorological mast. An ultrasonic sensor is also mounted on the mast. The objective of the test programme is to assess the effectiveness of SODAR and LIDAR wind speed measurement techniques under different operating regimes and atmospheric conditions. Results from the measurements will provide definitive data on the performance of the remote wind speed sensing techniques under test on complex terrain typical of many wind farm sites. Preliminary measurements based on data acquired during the initial measurement campaign are presented.

  12. Preliminary experimental results from a linear reciprocating magnetic refrigerator prototype

    International Nuclear Information System (INIS)

    A linear reciprocating magnetic refrigerator prototype was designed and built with the aid of an industrial partner. The refrigerator is based on the Active Magnetic Regenerative cycle, and exploits two regenerators working in parallel. The active material is Gadolinium in plates, 0.8 mm thick, for a total mass of 0.36 kg. The device is described and results about magnetic field and temperature span measurements are presented. The designed permanent magnet structure, based on an improved cross-type arrangement, generates a maximum magnetic field intensity of 1.55 T in air, over a gap of (13 × 50 × 100) mm3. The maximum temperature span achieved is 5.0 K, in a free run condition. -- Highlights: ► We give preliminary results from a linear reciprocating magnetic refrigerator prototype. ► The design is intended to process visualization and investigation. ► The prototype behavior gives us various suggestions to improve its general performance

  13. Magnetic resonance imaging urodynamics: technique development and preliminary results

    Directory of Open Access Journals (Sweden)

    Gustavo Borghesi

    2006-06-01

    Full Text Available OBJECTIVES: In this preliminary study we report the development of the video urodynamic technique using magnetic resonance imaging (MRI. MATERIALS AND METHODS: We studied 6 women with genuine stress urinary incontinence, diagnosed by history and physical examination. Urodynamic examination was performed on multichannel equipment with the patient in the supine position. Coughing and Valsalva maneuvers were performed at volumes of 150, 250 and 350 mL. Simultaneously, MRI was carried out by using 1.5 T GE Signa CV/i high-speed scanner with real time fluoroscopic imaging possibilities. Fluoroscopic imaging was accomplished in the corresponding planes with T2-weighted single shot fast spin echo sequences at a speed of about 1 frame per second. Both studies were recorded and synchronized, resulting in a single video urodynamic examination. RESULTS: Dynamic MRI with cine-loop reconstruction of 1 image per second demonstrated the movement of all compartment of the relaxed pelvis during straining with the concomitant registration of abdominal and intravesical pressures. In 5 patients, urinary leakage was demonstrated during straining and the Valsalva leak point pressure (VLPP was determined as the vesical pressure at leak subtracted from baseline bladder pressure. Mean VLPP was 72.6 cm H2O (ranging from 43 to 122 cm H2O. CONCLUSIONS: The concept of MRI video urodynamics is feasible. In a clinical perspective, practical aspects represent a barrier to daily use and it should be recommended for research purposes.

  14. In situ photoimmunotherapy for melanoma: preliminary clinical results

    Science.gov (United States)

    Naylor, Mark F.; Nordquist, Robert E.; Teauge, T. Kent; Perry, Lisa A.; Chen, Wei R.

    2006-02-01

    Although melanoma accounts for only 4% of skin cancer cases, it causes 79% of all skin cancer deaths. Patients with metastatic melanoma have a poor prognosis, and long term survival is only about 5% [1, 2]. Conventional therapies such as surgery and radiation therapy usually do not cure stage III or stage IV melanoma, while traditional chemotherapy is primarily palliative. Over the last decade we have been developing new methods for treating solid tumors like melanoma, first in animal models and now in humans. We present here preliminary results from a new technique that utilizes a combination of laser stimulation and drug therapy to stimulate brisk immunological responses in cases of advanced melanoma with cutaneous metastases. A high-power, near-infrared diode laser (805 nm) is used to kill tumors in situ and a topical toll-like receptor agonist (imiquimod cream, 5%) is used to intensify the resulting immunological response. This is essentially an in situ, tumor vaccine approach to treating solid tumors.

  15. The Myres Hill remote sensing intercomparison study: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Clive, P J M; Chindurza, I [SgurrEnergy Ltd, 79 Coplaw Street, Glasgow G42 7JG, Scotland (United Kingdom); Ravey, I; Bass, J [RES Group Ltd, James Blyth House, 7000 Academy Park, Glasgow, Scotland (United Kingdom); Boyle, R J; Jones, P [TUV NEL Ltd, East Kilbride, Glasgow G75 0QF, Scotland (United Kingdom); Lang, S J [Sustainable Energy Research Group, University College Cork (Ireland); Bradley, S [Mighty River Power, Level 14, 23-29 Albert Street, Auckland (New Zealand); Hay, L [Garrad Hassan and Partners Ltd, 2064 Maryhill Road, Glasgow G20 0AB, Scotland (United Kingdom); Oldroyd, A [Oldbaum Services Ltd, Schoolhouse, Brig o' Turk, Callander, Scotland (United Kingdom); Stickland, M [University of Strathclyde, 16 Richmond Street, Glasgow G1 1XQ, Scotland (United Kingdom)], E-mail: peter.clive@sgurrenergy.com

    2008-05-01

    Two remote sensing techniques (SODAR and LIDAR) have been developed for measuring wind speed and turbulence from ground level up to altitudes of 300 m or higher. Although originally developed in the defence sector, these techniques are now generating considerable interest in the renewable energy and meteorological sectors. Despite the benefits of these instruments they are not yet generally accepted for due diligence measurements by wind energy developers and financial institutions. There is a requirement for a series of independent assessments of these new metrology techniques, comparing their measurements with the approved cup-type anemometer readings. This is being addressed at TUV NEL's Myres Hill wind turbine test site in a measurement programme supported by the DIUS National Measurement Systems Measurement for Innovators scheme and a consortium of 21 industrial collaborators. Data from SODAR and LIDAR systems are being compared with results from cup-type anemometers mounted at different heights on an 80m meteorological mast. An ultrasonic sensor is also mounted on the mast. The objective of the test programme is to assess the effectiveness of SODAR and LIDAR wind speed measurement techniques under different operating regimes and atmospheric conditions. Results from the measurements will provide definitive data on the performance of the remote wind speed sensing techniques under test on complex terrain typical of many wind farm sites. Preliminary measurements based on data acquired during the initial measurement campaign are presented.

  16. The Myres Hill remote sensing intercomparison study: preliminary results

    International Nuclear Information System (INIS)

    Two remote sensing techniques (SODAR and LIDAR) have been developed for measuring wind speed and turbulence from ground level up to altitudes of 300 m or higher. Although originally developed in the defence sector, these techniques are now generating considerable interest in the renewable energy and meteorological sectors. Despite the benefits of these instruments they are not yet generally accepted for due diligence measurements by wind energy developers and financial institutions. There is a requirement for a series of independent assessments of these new metrology techniques, comparing their measurements with the approved cup-type anemometer readings. This is being addressed at TUV NEL's Myres Hill wind turbine test site in a measurement programme supported by the DIUS National Measurement Systems Measurement for Innovators scheme and a consortium of 21 industrial collaborators. Data from SODAR and LIDAR systems are being compared with results from cup-type anemometers mounted at different heights on an 80m meteorological mast. An ultrasonic sensor is also mounted on the mast. The objective of the test programme is to assess the effectiveness of SODAR and LIDAR wind speed measurement techniques under different operating regimes and atmospheric conditions. Results from the measurements will provide definitive data on the performance of the remote wind speed sensing techniques under test on complex terrain typical of many wind farm sites. Preliminary measurements based on data acquired during the initial measurement campaign are presented

  17. Preliminary results of centroiding experiment for the STEP mission

    Science.gov (United States)

    Li, Haitao; Li, Baoquan; Cao, Yang; Chen, Ding; Li, Ligang

    2015-08-01

    Search for Terrestrial Exo-Planet (STEP)[1] was originally proposed in 2013 by the National Space Science Center, Chinese Academy of Sciences, which is currently being under background engineering study phase in China. The STEP mission is a space astrometry telescope working at visible light wavelengths. The STEP aims at the nearby terrestrial planets detection through micro-arcsecond-level astrometry. Determination of the separation between star images on a detector with high precision is very important for astrometric exoplanets detection through the observation of star wobbles due to planets. The requirement of centroiding accuracy for STEP is 1e-5 pixel. A centroiding experiment have been carried out on a metrology testbed in open laboratory. In this paper, we present the preliminary results of determining the separations between star images. Without calibration of pixel positions and intra-pixel response, we have demonstrated that the standard deviation of differential centroiding is below 7.4e-3 pixel by the algorithm of linear corrected photon weighted means(LCPWM)[2,3]. For comparison, the photon weighted means(PWM) and Gauss fitting are also used in the data reduction. These results pave the way for the geometrical calibration and the intra-pixel quantum efficiency(QE) calibration of detector array equipment for micro-pixel accuracy centroiding.

  18. Analytic study of the Tadoma method: background and preliminary results.

    Science.gov (United States)

    Norton, S J; Schultz, M C; Reed, C M; Braida, L D; Durlach, N I; Rabinowitz, W M; Chomsky, C

    1977-09-01

    Certain deaf-blind persons have been taught, through the Tadoma method of speechreading, to use vibrotactile cues from the face and neck to understand speech. This paper reports the results of preliminary tests of the speechreading ability of one adult Tadoma user. The tests were of four major types: (1) discrimination of speech stimuli; (2) recognition of words in isolation and in sentences; (3) interpretation of prosodic and syntactic features in sentences; and (4) comprehension of written (Braille) and oral speech. Words in highly contextual environments were much better perceived than were words in low-context environments. Many of the word errors involved phonemic substitutions which shared articulatory features with the target phonemes, with a higher error rate for vowels than consonants. Relative to performance on word-recognition tests, performance on some of the discrimination tests was worse than expected. Perception of sentences appeared to be mildly sensitive to rate of talking and to speaker differences. Results of the tests on perception of prosodic and syntactic features, while inconclusive, indicate that many of the features tested were not used in interpreting sentences. On an English comprehension test, a higher score was obtained for items administered in Braille than through oral presentation. PMID:904318

  19. Preliminary results of a vapor extraction remediation in low permeability

    International Nuclear Information System (INIS)

    A pressurized underground pipeline ruptured and released approximately 80,000 gallons of JP-4 jet fuel in June, 1988 at Kelly AFB, Texas. The JP-4 spill contaminated unsaturated silt and clay-rich soils. A December 1990 Soil Vapor Extraction (SVE) pilot-scale test at the site showed that SVE was feasible in low permeability soils. The pilot test utilized one vapor extraction well and 12 multi-depth piezometers. Application of 72 inches of water vacuum (iwv) at the extraction well caused pressure drawdowns at piezometers within 20 feet of the extraction well. Pressure data indicated an extraction well radius of influence of 20 feet at a flow rate of 13 standard cubic feet per minute (scfm). The maximum hydrocarbon extraction rate was 286 pounds per day. A full-scale SVE system was designed and installed. Preliminary results indicate an initial hydrocarbon extraction rate of 29 pounds per hour which decreased to approximately 12 pounds per hour after 2 months of operation. Concurrently, the system air flow rate increased from 300 scfm to 500 scfm, and wellhead vacuums dropped from 70 iwv to 23 iwv. In-situ biodegradation of jet fuel is being studied at the site. An in-situ respiration test indicated a biodegradation rate of about 1 milligram of JP-4 removed per kilogram of soil per day

  20. Auroral Spatial Structures Probe Sub-Orbital Mission Preliminary Results

    Science.gov (United States)

    Pratt, J.; Swenson, C.; Martineau, R. J.; Fish, C. S.; Conde, M.; Hampton, D.; Crowley, G.

    2015-12-01

    The NASA Auroral Spatial Structures Probe, 49.002, was launched January 28, 2015 from the Poker Flat Research Range into active aurora over the northern coast of Alaska. The primary objective of this mission was to determine the contribution of small spatial and temporal scale fluctuations of the electric fields to the larger-scale energy deposition processes associated with the aurora. The Auroral Spatial Structures Probe Sub-Orbital Mission consisted of a formation of 7 spacecraft (a main payload with 6 deployable sub-payloads) designed for multiple temporally spaced co-located measurements of electric and magnetic fields in the earth's ionosphere. The mission was able to make observations at a short time scale and small spatial scale convergence that is unobservable by either satellite or ground-based observations. The payloads included magnetometers, electric field double probes, and Langmuir probes as well as a sweeping impedance probe on the main payload. We present here preliminary results from the measurements taken that hint at the underlying spatial structure of the currents and energy deposition in the aurora. The Poynting flux derived from the observations is shown and implications are discussed in terms of the contribution of small spatial scale, rapid temporal scale fluctuations in the currents that deposit energy in the auroral region. Funding provided by NASA Grants NNX11AE23G and NNX13AN20A.

  1. Laboratory study of corrosion of steam generator tubes: Preliminary results

    International Nuclear Information System (INIS)

    The secondary side intergranular attack (IGA) and intergranular stress corrosion cracking (IGSCC) of steam generator tubes often occurs in crevices where impurities are concentrated, due to local elevated temperatures and restricted water flow. From the analysis of tubes pulled from plants, it is believed that alumino-silicates deposits and/or organic species may play a role in the development of IGA in near neutral environments. New observations suggest that similar environments and similar processes are operative inside the corroded grain boundaries. A former study using autoclave tests was mainly devoted to the formation of alumino-silicate deposits similar to those observed in plants. The present work pursued the study of local environments responsible for IGA/SC. It confirms former results on the catalytic decomposition of organic species into acetates and presents more details on the mechanism of formation of alumino-silicate deposits on alloy 600, particularly on the role of iron and, to a lesser extent, nickel cations. It was showed that, under the alumino-silicate deposits and in the presence of some organic species, a non-protective chromium rich layer may grow instead of the usual protective spinel oxide. The mechanism responsible for the formation of this layer is believed to involve interaction between iron and, to a lesser extent, nickel with silica and/or possible interaction between chromium and acetates. Preliminary capsule tests indicate that these conditions may induce the initiation of IGA

  2. Paleomagnetism of subsurface Trenton Group carbonates, southwestern Ontario : preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Garner, N.; Cioppa, M.T. [Windsor Univ., ON (Canada). Dept. of Earth Sciences

    2004-07-01

    The oil and gas industry in Canada and the United States has expressed renewed exploration interest in the Ordovician Trenton and Black River Group carbonates of southwestern Ontario. The hydrocarbon reservoirs in the area are associated with non-porous limestones and isolated areas of dolomitization. Paleomagnetic studies have been conducted on unoriented core from the dolomite-rich Hillman Field to determine if previously characterized dolomitic phases can be distinguished magnetically. More than 200 specimens were collected from a single well, providing a nearly complete section through the Sherman Falls Formation. Preliminary measurements were made using a multi-step alternating field or thermal demagnetization sequence. There were at least two magnetization components in the specimens measured. These included a normal polarity low temperature/low coercivity remanent magnetization, and a reversed polarity characteristic remanent magnetization (ChRM). Results suggest that pyrrhotite and magnetite is present. Although the origin of the high temperature magnetization has not been determined, the generally low temperature magnetization of the ChRM suggests that the magnetization is the Permian Kiaman overprint that is observed in the Appalachian Basin.

  3. Genetic Variation A mong European Lophodermium piceae Populations - Preliminary Results

    Directory of Open Access Journals (Sweden)

    MÜLLER, Michael M.

    2007-01-01

    Full Text Available Lophodermium piceae is a common needle endophyte of Norway spruce (Picea abies. The aim of the present study was to examine the degree of differentiation within and among European populations separated by various distances and geographical obstacles. For this purpose, populations (including > 10 isolates/subpopulation were collected along a north-south transect stretching from the northern timberline in Finnish Lapland to the southern border of the distribution area of Norway spruce in northern Italy. Differentiation between L. piceae populations was determined from DNA sequences of three genetic markers. One of the markers was the internal transcribed spacer (ITS of the ribosomal DNA and the other two (LP1 and LP2 were based on sequence characterized amplified regions (SCAR designed for L. piceae. Preliminary results including sequences of Finnish, Swiss and Italian isolates show low differentiation among populations. According to analysis of molecular variance the among population variation was 1%, 5% and 0% in ITS, LP1 and LP2 markers, respectively.

  4. SWCX Emission from the Helium Focusing Cone - Preliminary Results

    Science.gov (United States)

    Snowden, S. L.; Kuntz, K. D.; Collier, M. R.

    2008-01-01

    Preliminary results from an XMM-Newton campaign to study solar wind charge exchange (SWCX) emission from the heliospheric focusing cone of interstellar helium are presented. The detections of enhanced O VII and O VIII emission from the cone are at the 2(sigma) and 4(sigma) levels. The solar wind charge exchange (SWCX) emission in the heliosphere not associated with distinct objects (e.g., comets and planets including exospheric material in and near Earth s magnetosheath) is proportional to the flux of the solar wind and the space density of neutral material. The neutral material originates in the interstellar medium (ISM) and passes through the solar system due to the relative motion of the Sun and the ISM. The flow of the neutral material through the solar system is strongly perturbed by the Sun both by gravity and by radiation pressure. Because of the relative radiative scattering cross sections and the effect of solar gravitation the density of interstellar hydrogen near the Sun is reduced while interstellar helium is gravitationally focused. This creates a helium focusing cone downstream of the Sun [e.g., 1, and references therein].

  5. Preliminary results of the LAT Calibration Unit beam tests

    International Nuclear Information System (INIS)

    The calibration strategy of the GLAST Large Area Telescope (LAT) combines analysis of cosmic ray data with accelerator particle beams measurements. An advanced Monte Carlo simulation of the LAT, based on the Geant4 package, was set up to reproduce the LAT response to such radiation and to benchmark the event reconstruction and the background rejection strategy before launch and during operation. To validate the LAT simulation, a massive campaign of beam tests was performed between July and November 2006, in parallel with the LAT integration and test, on the LAT Calibration Unit. This is a detector built with spare flight modules and flight-like readout electronics, which was exposed to a large variety of beams, representing the whole spectrum of the signal that will be detected by the LAT, using the CERN and the GSI accelerator facilities. Beams of photons (0 - 2.5 GeV), electrons (1 - 300 GeV), hadrons (π and p, a few GeV - 100 GeV) and ions (C; Xe, 1.5 GeV/n) were shot through the CU to measure the physical processes taking place in the detector and eventually fine-tune their description in the LAT Monte Carlo simulation. This paper describes the motivations and goals of the test runs, the many different experimental setups used, the measured detector performance and preliminary results of the LAT Monte Carlo validation

  6. Preliminary Results of the LAT Calibration Unit Beam Tests

    International Nuclear Information System (INIS)

    The calibration strategy of the GLAST Large Area Telescope (LAT) combines analysis of cosmic ray data with accelerator particle beams measurements. An advanced Monte Carlo simulation of the LAT, based on the Geant4 package, was set up to reproduce the LAT response to such radiation and to benchmark the event reconstruction and the background rejection strategy before launch and during operation. To validate the LAT simulation, a massive campaign of beam tests was performed between July and November 2006, in parallel with the LAT integration and test, on the LAT Calibration Unit. This is a detector built with spare flight modules and flight-like readout electronics, which was exposed to a large variety of beams, representing the whole spectrum of the signal that will be detected by the LAT, using the CERN and the GSI accelerator facilities. Beams of photons (0 - 2.5 GeV), electrons (1 - 300 GeV), hadrons (p and p, a few GeV - 100 GeV) and ions (C Xe, 1.5 GeV/n) were shot through the CU to measure the physical processes taking place in the detector and eventually fine-tune their description in the LAT Monte Carlo simulation. This paper describes the motivations and goals of the test runs, the many different experimental setups used, the measured detector performance and preliminary results of the LAT Monte Carlo validation

  7. Favourable results of Mohs micrographic surgery for basal cell carcinoma

    DEFF Research Database (Denmark)

    Gniadecki, Robert; Glud, Martin; Mortensen, Kia;

    2015-01-01

    INTRODUCTION: Basal cell carcinoma (BCC) is the most common malignant neoplasm with an annual incidence approaching 200/100,000 person-years. Mohs micrographic surgery (MMS) is widely used in North America and in Europe for treatment of BCC. This technique ensures radical tumour removal, sparing of...... to 40% smaller skin defects than standard excisions with 4 or 6 mm margins. Closure of skin defects was achieved by side-to-side closure in 49% and by local flaps in 40%. There were no relapses during the observation time. The safety, cosmetic and functional outcome were excellent. CONCLUSIONS: We...

  8. Fast neutron therapy of bronchus carcinoma: the pooled results from two european centres

    International Nuclear Information System (INIS)

    The Berlin-Buch and Heidelberg centres used fast neutron therapy in bronchial carcinomas. The neutron source was a cyclotron in Berlin-Buch/Rossendorf and a d-t generator in Heidelberg. Three hundred twelve patients with inoperable bronchial carcinoma were treated with fast neutron therapy alone or in combination with photons. The results were then compared with those obtained from 594 patients treated only with photons. Altogether, 788 were treated in Berlin-Buch and 188 in Heidelberg. The results suggest that neutron therapy for bronchial carcinoma can be a good alternative in curative and palliative situations in the early stages. (author)

  9. Single-Antenna Microwave Ablation Under Contrast-Enhanced Ultrasound Guidance for Treatment of Small Renal Cell Carcinoma: Preliminary Experience

    International Nuclear Information System (INIS)

    The purpose of this study was to determine the safety, effectiveness, and feasibility of microwave ablation (MWA) of small renal cell carcinomas (RCCs) in selected patients. Institutional review board and informed consent were obtained. From December 2007 to January 2009, 12 patients (8 male, 4 female) were enrolled in a treatment group, in which percutaneous MWA of small RCCs was performed under contrast-enhanced ultrasound guidance. The tumors were 1.7-2.9 cm in diameter (mean diameter, 2.0 cm).Therapeutic effects were assessed at follow-up with computed tomography. All patients were followed up for 3-14 months (mean, 6 months) to observe the therapeutic effects and complications (according to SIR classification). Assessment was carried out with CT imaging. No severe complications or unexpected side effects were observed after the MWA procedures. In all cases technical success was achieved. Clinical effectiveness was 100%; none of the patients showed recurrence on imaging. In conclusion, our preliminary results support the use of MWA for the treatment of small renal tumors. This technology can be applied in select patients who are not candidates for surgery, as an alternative to other ablative techniques.

  10. Results of radiation therapy for carcinoma of the uterine cervix

    International Nuclear Information System (INIS)

    Fifty-nine consecutive patients who were treated with radiation therapy for carcinoma of the uterine cervix between April 1982 and December 1986 were reviewed. Twelve patients were treated with low dose-rate intracavitary irradiation using radium-226, and 46 were treated with high dose-rate irradiation using a remote afterloading system combined with external irradiation, and the other one was treated with external irradiation alone. The 5-year-survival rates for stage Ib, IIa, IIb, IIIb, and IVa were 77.8, 85.7, 87.5, 45.5 and 40.0%, respectively. The 5-year-survival rates for the low and high dose-rates irradiation were 66.7 and 73.9%, respectively. The most common complication of radiation therapy was rectal bleeding, which required conservative treatment (grade 2) in 11 (18.6%). The morbidities for the low and high dose-rates irradiation were similar. The causes of death in 17 patients were local recurrence in 14, metastases in 2 and other specified in one. These findings suggest that high dose-rate intracavitary irradiation is as effective as low dose-rate irradiation for carcinoma of the uterine cervix, and that further efforts for controlling the local tumors with stage IIIb disease without an increased rate of side-effects is required. (author)

  11. Varfarin in the complex treatment of antiphospholipid syndrome: preliminary results

    Directory of Open Access Journals (Sweden)

    T M Reshetnyak

    2003-01-01

    Full Text Available Objective. To assess efficacy and tolerance of varfarin in prophylaxis and therapy of thrombotic complications in patients with antiphospholipid syndrome (APS. Methods. 20 pts with APS (5 male and 15 female received varfarin during a year. 8 of them had primary APS (PAPS and 12 -systemic lupus erythematosus with APS (SLE+APS. 2 other pts (I with SLE+APS and I with PAPS received varfarin during the last 4 years. Nobody from 9 pts with PAPS received corticosteroids (CS. In SLE+APS pts CS dose varied from 4 to 20 mg/day and was not increased during follow up. During the study prothrombine time (PT was examined with thromboplastin ( manufactured by Renam having international sensitivity index 1,2 and international normalization relation (INR. Depending on treatment scheme APS pts were divided into 3 groups. Group 1 included 8 pts with INR<2,0, Group 2-7 with INR >3,0, group 3 - 7 pts with INR<2,0 receiving as additional treatment thrombo ASS 100 mg/day and vasonit from 600 to 1200 mg/day. Results. Two pts with INR = 1,8 had thrombosis recurrence (due to leg thrombophlebitis. There were no recurrences in other groups. 2 from 22 pts had "large" bleedings. "Small" bleedings episodes were noted in 7 from 22 pts. Largely that were subcutaneous bleedings (in 4 pts no more than 5 cm of size. Two pts receiving varfarin with INR 1,8 and 2,4 had renal colic. Conclusion. Our preliminary results prove the necessity of inclusion of varfarin in the treatment of pts with APS and thrombosis but intensive anticoagulant effect is not always desired.

  12. Preliminary results of the XR2-1 experiment

    Energy Technology Data Exchange (ETDEWEB)

    Gauntt, R.O.; Helmick, P.H. [Sandia National Labs., Albuquerque, NM (United States); Humphries, L. [SAIC, Albuquerque, NM (United States)

    1996-03-01

    The XR2-1 (Ex-Reactor) experiment, investigating metallic core-melt relocation in boiling water reactor geometry, was performed on October 12, 1995, following two previous simpler XR1-series tests in August and November of 1993. The XR2-1 test made use of a highly detailed replication of the lower region of the BWR core, including the control blade and channel box structures, fuel rods, fuel canister nosepieces, control blade velocity limiter, and fuel support pieces, in order to investigate a key core melt progression uncertainty for BWR Station Blackout type accidents. The purpose of this experiment program is to examine the behavior of downward-draining molten metallic core materials in a severe reactor accident in a dry BWR core, and to determine conditions under which the molten materials drain out of the core region, or freeze to form blockages in the lower portion of the core. In the event that the draining metallic materials do not form stable blockages in the lower core region, and instead erode the lower core structures such as the lower core plate, then the subsequent core melt progression processes may proceed quite differently than was observed in the TMI-2 accident, with correspondingly different impact on vessel loading and vessel release behavior. The results of the Ex-Reactor tests are preliminary. All of the tests conducted have shown a significant degree of channel box destruction induced by the draining control blade materials. The XR2-1 test further showed that the draining zircaloy melt causes significant disruption of the fuel rod geometry. All of the tests have shown tendencies to form interim blockages as the melts temporarily freeze, but that these blockages re-melt, assisted by eutectic interactions, resulting in the sudden draining of accumulated metallic melt pools.

  13. Preliminary study for non – invasive optical detection of squamous and basal cell carcinomas

    Directory of Open Access Journals (Sweden)

    Ali Ahmed Mohammed

    2012-11-01

    Full Text Available Abstract Background The early detection of skin cancer may highly increase the chances of its healing. One of the non-invasive methods of such detection based on the Oblique- Incidence Diffuse Reflectance (OIDR measurements of the reflected diode laser light from the skin. In this research we designed and implemented the OIDR reflectometry measuring system with a 650 nm diode laser source to aid physicians in diagnosing both squamous cell carcinomas (SCC and basal cell carcinomas(BCC. Method The laser is delivered obliquely to the skin surface by an optical fiber fitted through a tube holder of CCD camera. The diffused reflected laser light from the skin is captured by the CCD camera and sent to a computer, which is supplied by a specially prepared Matlab program to analyze these images in order to decide in a time whether the lesion is malignant or benign. Fifty cases were diagnosed under supervision of the consultant section of The Governmental Specialized Marjan Teaching Hospital – MOH – Iraq. Result The fifty diagnosed cases by this technique, the results were 90% accurate. Conclusion The method of laser oblique-incidence diffuse reflectance (OIDR combined with using the developed algorithms that have high classification rates may prove useful in the clinic as the process is fast, noninvasive and accurate.

  14. Simultaneous chemoradiotherapy with Taxol/Carboplatin in advanced head and neck cancer. Preliminary results

    International Nuclear Information System (INIS)

    Background: The purpose of simultaneous chemoradiotherapy is to increase local-regional control and to decrease the incidence of distant metastases. Regimens containing cisplatin/5-FU chemotherapy are widely accepted as standard treatment in advanced head and neck cancer. Most studies reported promising response and survival data, but also severe mucosal toxicity. In recent years the newly developed drug Taxol demonstrated interesting activity in head and neck cancer as a single agent and as well in combination drug regimens. In the present outpatient phase-II trial we investigated the combination of Taxol/carboplatin with 40 Gy radiotherapy in a neoadjuvant setting of operable Stage-III/IV squamous cell carcinoma of the oral cavity and oropharynx. Patients and Methods: Twelve patients were enrolled in this ongoing trial with a projected number of 30 patients and received 5 cycles of weekly Taxol (40 mg/m2) and carboplatin (AUC 1.5) with conventional radiotherapy (40 Gy). Within 3 to 4 weeks after chemoradiotherapy resection of the primary tumor and the regional neck nodes was performed. Results: So far 12 patients were evaluable for toxicity and response. Complete response was noted in 8/12 patients (Cr 66%). In 6/10 patients (60%) complete pathologic response was documented in the resection specimens. Conclusion: Our preliminary results demonstrated excellent clinical and pathological response rates of concurrent Taxol/carboplatin and radiotherapy as preoperative treatment modality in advanced oral and oropharyngeal cancer. (orig.)

  15. Preliminary Characterization Results from the DebriSat Project

    Science.gov (United States)

    Rivero, M.; Shiotani, B.; Kleespies, J.; Toledo-Burdett, R.; Moraguez, M.; Carrasquila, M.; Fitz-Coy, N.; Liou, J.-C.; Sorge, M.; Huynh, T.

    2016-01-01

    preliminary results presented. Additionally, lessons learned from the implemented automations and their impacts on the integrity of the results are discussed.

  16. Autonomous Ozone and Aerosol Lidar Platform: Preliminary Results

    Science.gov (United States)

    Strawbridge, K. B.

    2014-12-01

    Environment Canada is developing an autonomous tropospheric ozone and aerosol lidar system for deployment in support of short-term field studies. Tropospheric ozone and aerosols (PM10 and PM2.5) are important atmospheric constituents in low altitude pollution affecting human health and vegetation. Ozone is photo-chemically active with nitrogen oxides and can have a distinct diurnal variability. Aerosols contribute to the radiative budget, are a tracer for pollution transport, undergo complex mixing, and contribute to visibility and cloud formation. This particular instrument will employ two separate lidar transmitter and receiver assemblies. The tropospheric ozone lidar, based on the differential absorption lidar (DIAL) technique, uses the fourth harmonics of a Nd:YAG laser directed into a CO2 Raman cell to produce 276 nm, 287nm and 299 nm (first to third Stokes lines) output wavelengths. The aerosol lidar is based on the 3+2 design using a tripled Nd:YAG to output 355 nm, 532 nm and 1064nm wavelengths. Both lidars will be housed in a modified cargo trailer allowing for easy deployment to remote areas. The unit can be operated and monitored 24 hours a day via an internet link and requires an external power source. Simultaneous ozone and aerosol lidar measurements will provide the vertical context necessary to understand the complex mixing and transformation of pollutants - particularly when deployed near other ground-based in-situ sensors. Preliminary results will be shown from a summer field study at the Centre For Atmospheric Research Experiments (CARE).

  17. COSMIC EVOLUTION OF DUST IN GALAXIES: METHODS AND PRELIMINARY RESULTS

    Energy Technology Data Exchange (ETDEWEB)

    Bekki, Kenji [ICRAR, M468, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009 (Australia)

    2015-02-01

    We investigate the redshift (z) evolution of dust mass and abundance, their dependences on initial conditions of galaxy formation, and physical correlations between dust, gas, and stellar contents at different z based on our original chemodynamical simulations of galaxy formation with dust growth and destruction. In this preliminary investigation, we first determine the reasonable ranges of the most important two parameters for dust evolution, i.e., the timescales of dust growth and destruction, by comparing the observed and simulated dust mass and abundances and molecular hydrogen (H{sub 2}) content of the Galaxy. We then investigate the z-evolution of dust-to-gas ratios (D), H{sub 2} gas fraction (f{sub H{sub 2}}), and gas-phase chemical abundances (e.g., A {sub O} = 12 + log (O/H)) in the simulated disk and dwarf galaxies. The principal results are as follows. Both D and f{sub H{sub 2}} can rapidly increase during the early dissipative formation of galactic disks (z ∼ 2-3), and the z-evolution of these depends on initial mass densities, spin parameters, and masses of galaxies. The observed A {sub O}-D relation can be qualitatively reproduced, but the simulated dispersion of D at a given A {sub O} is smaller. The simulated galaxies with larger total dust masses show larger H{sub 2} and stellar masses and higher f{sub H{sub 2}}. Disk galaxies show negative radial gradients of D and the gradients are steeper for more massive galaxies. The observed evolution of dust masses and dust-to-stellar-mass ratios between z = 0 and 0.4 cannot be reproduced so well by the simulated disks. Very extended dusty gaseous halos can be formed during hierarchical buildup of disk galaxies. Dust-to-metal ratios (i.e., dust-depletion levels) are different within a single galaxy and between different galaxies at different z.

  18. Intraspecific variability of European larch for wood properties: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Paques, L.E.; Rozenberg, P. [Institut National de Recherches Agronomiques (INRA), 45 - Olivet (France). Station d`Amelioration des Arbres Forestiers

    1995-12-31

    Wood properties of several natural populations of European larch (Larix decidua Mill) were determined from samples collected in one replicate of the II. International IUFRO provenance experiment, planted in Brittany in 1959. According to provenances, proportion of heartwood ranges from 35 to 58% of basal area, basic density from 442 to 505 g/dm{sup 3} and Young modulus of elasticity from 8474 to 14522 MPa. Positive correlations between girth and heartwood proportion and between wood density and modulus of elasticity but negative correlations between ring width and both density and MOE have been found both at the individual and at the population levels. Variability between and within provenances is high for two major traits (proportion of heartwood and Young modulus of elasticity) for which a SW - NE gradient is shown. For wood density parameters including pilodyn, a greater homogeneity is observed. Besides a now largely recognized superiority for growth traits, Central European populations from the Sudetan Mountains and Central Poland would also produce wood with better properties. On the reverse, Alpine populations from the French Alps growing at low elevations have a slower growth, a denser wood with less heartwood and less strength. Used as a control, the hybrid larch origin (Larix x eurolepis) represents the best compromise for wood properties with the highest strength but an average wood density and one of the highest proportion of heartwood. These preliminary results must be confirmed from a larger set of provenances and completed with other major wood properties such as durability and shrinkage. 17 refs, 2 figs, 6 tabs

  19. Mycodiversity in marine sediments contaminated by heavy metals: preliminary results

    Science.gov (United States)

    Zotti, Mirca; Carbone, Cristina; Cecchi, Grazia; Consani, Sirio; Cutroneo, Laura; Di Piazza, Simone; Gabutto, Giacomo; Greco, Giuseppe; Vagge, Greta; Capello, Marco

    2016-04-01

    .6 CFU per gram of sediments. The maximum value of 11 CFU g-1 has been recorded in two stations (off the Sestri Levante Tombolo), while the minimum value has been recorded closer to the coast. As concern qualitative results, the most recurrent genera are Aspergillus and Penicillium. These data confirm the occurrence of a mycobiota in these heavy metal contaminated sediments. Our preliminary results are a first contribution to the knowledge of presence of microfungi in marine sediments, and propel us to increase our research in order to find out new organisms for bioremediation purpose.

  20. Anisotropy of Pore Structure and Permeability in Granite: Preliminary Results

    Science.gov (United States)

    Onishi, C. T.; Shimizu, I.; Mizoguchi, K.; Uehara, S.; Shimamoto, T.

    2001-12-01

    of 25- 200 MPa, with pore pressure kept around 20 MPa. Preliminary results indicate relatively high permeability for undeformed biotite granite, about 10-16m2 at the initial confining pressure (Pc=30MPa), and with a gradual decrease to 10-17m2 at the highest Pc(=198MPa). The fractured sample with cataclastic seams has lower permeability (in the order of 10-17 to 10-18m2) possibly due to crack sealing by hydrothermal activities.

  1. Dynamics of the Caspian Sea: Preliminary results of isotope studies

    International Nuclear Information System (INIS)

    The water level of the Caspian Sea, the world's largest inland water body, rose by approximately 2 m within the last 20 years. To explore the potential of isotope techniques for studying the water balance and dynamics of the Caspian Sea and aspects related to the recent sea level rise, two research-training cruises were carried out in September 1995 and 1996 within the framework of an IAEA technical co-operation project. The paper presents a preliminary evaluation of the results obtained so far. By correlating sea level fluctuations and freshwater inflow variations observed in previous studies, it has been found that changes of the sea level are caused by changes in the water budget, mainly in the river input. The water of the Caspian Sea is enriched in oxygen-18 with respect to the total inflow (rivers plus precipitation) by about 9 per mille. The vertical distribution of δ18O observed in the southern and central basins of the Caspian Sea indicates that the main water body of the sea (between 200 m and 800 m depth) is enriched in oxygen-18 with respect to the surface layer by approximately 0.3 per mille. This enrichment suggests that water at depth most probably represents the previous low level stand of the Caspian Sea (1950-1977) and that the total inflow exceeded the evaporation by about 10% during the recent sea level rise. Vertical temperature and salinity gradients observed during the 1995 and 1996 expeditions suggest that deep water exchange in the central and southern basins of the Caspian Sea cannot be triggered by cooling of surface water alone but also requires an increase of salinity. The presence of bomb tritium and tritiogenic helium-3 in the deep water of the central and southern basins points to rather intense vertical water exchange in both basins. The water ages calculated from tritium and helium-3 increase from shallow to deep water in both basins; near the bottom, a maximum model age of some 20 to 25 years was. (author) obtained

  2. Imaging of brain metastases of bronchial carcinomas with 7 T MRI. Initial results

    Energy Technology Data Exchange (ETDEWEB)

    Moenninghoff, C. [Universitaetsklinikum Essen (Germany). Inst. fuer Diagnostische und Interventionelle Radiologie und Neuroradiologie; Maderwald, S.; Theysohn, J.M.; Kraff, O.; Ladd, S.C.; Wanke, I. [Universitaetsklinikum Essen (Germany). Inst. fuer Diagnostische und Interventionelle Radiologie und Neuroradiologie; Duisburg-Essen Univ. (Germany). Erwin L. Hahn Inst. fuer Magnetresonanztomographie; Schuett, P.; Gauler, T. [Universitaetsklinikum Essen (Germany). Klinik fuer Innere Medizin, Konservative Onkologie; Ladd, M.E. [Duisburg-Essen Univ. (Germany). Erwin L. Hahn Inst. fuer Magnetresonanztomographie

    2010-09-15

    Purpose: To compare the depiction of brain metastases of bronchial carcinomas on susceptibility-weighted and contrast-enhanced images with 7 T and at 1.5 T MRI. Materials and Methods: Twelve patients with brain metastases of bronchial carcinomas underwent 7 T and 1.5 T MRI. Minimum intensity projections (MinIP) of a 1.5 T SWI sequence (voxel size = 0.9 x 0.9 x 2.0 mm{sup 3}) were compared to 7 T SWI MinIPs (voxel size = 0.4 x 0.4 x 1.5 mm{sup 3}). A T 1-w 3D MPRAGE at 1.5 T (voxel size = 1 x 1 x 1 mm{sup 3} after double-dose (DD) gadoterate meglumine, Gd-DOTA) was compared to a 7 T MPRAGE sequence (voxel size = 0.7 x 0.7 x x 0.7 mm{sup 3}, single dose (SD) Gd-DOTA) in all patients, and to DD Gd-DOTA in 6 patients after a 10 minute delay. The number of intracranial microhemorrhages in SWI MinIPs and the number of contrast-enhancing metastases in MPRAGE images were compared in each patient grouped into three size ranges ({<=} 2 mm, > 2 mm and < 6 mm, {>=} 6 mm) by two radiologists in consensus. Results: In all 12 patients the 7 T SWI with spatially higher resolution allowed the identification of 87 versus 67 cerebral microhemorrhages at 1.5 T. 7 T T 1-w images after SD Gd-DOTA depicted 198 brain metastases versus 238 at 1.5 T after DD Gd-DOTA. After doubling the contrast dose in six patients, 4 additional brain metastases were identified at 7 T. Conclusion: Our preliminary results indicate that despite the higher spatial resolution the detection of brain metastases on 7 T MPRAGE images is almost equal to 1.5 T MPRAGE images. The 7 T SWI sequence with spatially higher resolution allowed the detection of 20 % more microhemorrhages in brain metastases compared to the 1.5 T SWI sequence. (orig.)

  3. Preliminary Results from SCEC Earthquake Simulator Comparison Project

    Science.gov (United States)

    Tullis, T. E.; Barall, M.; Richards-Dinger, K. B.; Ward, S. N.; Heien, E.; Zielke, O.; Pollitz, F. F.; Dieterich, J. H.; Rundle, J. B.; Yikilmaz, M. B.; Turcotte, D. L.; Kellogg, L. H.; Field, E. H.

    2010-12-01

    realistic fault geometies and slip rates taken from California, excluding the Cascadia subduction zone. In order to make as close comparisons between the simulators as possible we have developed shared data formats for both input and output and a growing set of tools that can be used to make statistical comparisons between the simulator outputs. To date all five simulators have run a Northern California fault model and are in various stages of working on an All California fault model. The plan in the near future is to run them on the UCERF2 fault model. Initial comparisons show significant differences among the simulators and some differences from observed earthquake statistics. However, it is too early in the process to infer too much from these preliminary results. For example, the differences in how each simulator treats fault friction means that they may each need to use values for the assumed stress drops that are better tuned to their approach than are the common values used in the first comparison.

  4. Results of radiation therapy for squamous cell carcinoma of vulva

    International Nuclear Information System (INIS)

    From 1962 to 1982, 20 cases of patients with squamous cell carcinoma of the vulva were treated by radiation alone at National Cancer Center Hospital, Tokyo. 80% (16/20) of these cases were over 60 years old. Treatment was made by interstitial irradiation (Radium needle or Au-Grain) and external irradiation (Betatron electron or Linac X-rays), alone or with various combinations. As for the stage of these cases, Stage I was 3 cases (15%), Stage II was 5 (25%) and Stage III was 12 (60%). Serious complications after treatment were observed in 15% (3/20) and all cases were treated with external irradiation alone. The 5 year survival rates by stage were as follows; Stage I 100% (3/3), Stage II 50% (2/4) and Stage III 22.2% (2/9). Surgery is considered the treatment of choice in this disease. However, radiation therapy may be indicated when the tumor has extended beyond the limit of surgical resections; when distant metastases are present; when the patient's general condition precludes surgery, or when surgery is refused. (author)

  5. Results of radiation therapy for squamous cell carcinoma of vulva

    Energy Technology Data Exchange (ETDEWEB)

    Tsukiyama, Iwao; Kakehi, Masae; Ono, Ryosuke (National Cancer Center, Tokyo (Japan). Hospital)

    1984-04-01

    From 1962 to 1982, 20 cases of patients with squamous cell carcinoma of the vulva were treated by radiation alone at National Cancer Center Hospital, Tokyo. 80% (16/20) of these cases were over 60 years old. Treatment was made by interstitial irradiation (Radium needle or Au-Grain) and external irradiation (Betatron electron or Linac X-rays), alone or with various combinations. As for the stage of these cases, Stage I was 3 cases (15%), Stage II was 5 (25%) and Stage III was 12 (60%). Serious complications after treatment were observed in 15% (3/20) and all cases were treated with external irradiation alone. The 5 year survival rates by stage were as follows; Stage I 100% (3/3), Stage II 50% (2/4) and Stage III 22.2% (2/9). Surgery is considered the treatment of choice in this disease. However, radiation therapy may be indicated when the tumor has extended beyond the limit of surgical resections; when distant metastases are present; when the patient's general condition precludes surgery, or when surgery is refused.

  6. Preliminary results of the PREFER FP7 Project

    Science.gov (United States)

    Fusilli, Lorenzo; Laneve, Giovanni; De Bonis, Roberto; Sebastian, Ana; Ferrucci, Fabrizio; Oliveira, Sandra

    2014-05-01

    The need to improve the information and intelligence support for forest fire prevention is widely recognized. Fire prevention is still the most cost-effective strategy when compared to firefighting and extinguishing that are costly, local, and triggered only in response to already ongoing crises. PREFER project, funded under the EU FP7 (G.A. 312931), intends to contribute at responding to such a pragmatic need of southern Europe's forests by: providing timely information products based on the exploitation of all available spacecraft sensors, offering a portfolio of products focused on pre- and post-crisis forest fire emergency, suitable for the users in the different countries of the European Mediterranean area. The PREFER Service portfolio consists of two main services: 1. Information Support to Fire Preparedness/Prevention Phase" (ISP) Service 2. Information Support to Fire Recovery/Reconstruction Phase" (ISR) Service This service is already at an advanced stage having completed the first year of activity. During this time several products have been consolidated: seasonal fuel maps; daily and seasonal fire hazard maps; seasonal risk maps; prescribed fire maps. This paper aims at presenting the preliminary results of the research activity carried out in the framework of the PREFER project, focusing, in particular, on these recalled above. As for Fire Risk and Hazard assessment, many indexes have been developed in the last years. Hardly any of them uses data derived from satellite images. The FPI index is an exception to this rule which, in addition, makes use of meteorological data. In spite of being a very complete index, the FPI still allows room for improvement which justify the interest of PREFER in it. PREFER's innovative approach to FPI will allow taking into account the effect of solar illumination conditions in determining the humidity present in the dead vegetation, and therefore its proneness to burn. PREFER innovation also focus in allowing the index to

  7. Metabolic syndrome in rheumatoid arthritis: role of adiponectin (preliminary results

    Directory of Open Access Journals (Sweden)

    Yulia Nikolaevna Gorbunova

    2013-01-01

    were encountered with the same frequency in early- and end-stage RA. The early RA group showed a correlation between SDAI (r = -0.34, body mass index (r = -0.41, high-density lipoprotein cholesterol (r = 0.33, erythrocyte sedimentation rate (r =-0.35, and adiponectin. The >2-year RA group displayed no relationship between adipokins, activity markers, and metabolic disturbances. Conclusion. The preliminary results suggest the high rate of MS in patients with a high level of early RA disease activity untreated with disease-modifying antirheumatic drugs, thus determining the high risk of CVEs just at disease onset. The role of adiponectin in the development of MS, CVEs in rheumatic diseases remains to be solved, which is the subject of further investigations. It is possible that normalization of adiponectin concentrations may promote reductions in the incidence of CVD, mortality rates due to atherosclerosis-induced CVEs, and the prevalence of MS and insulin resistance.

  8. Results of Surgical Therapy in Patients with Medullary Thyroid Carcinoma.

    Science.gov (United States)

    Vlad, Mihaela; Zosin, Ioana; Timar, Bogdan; Lazar, Fulger; Vlad, Adrian; Timar, Romulus; Cornianu, Marioara

    2016-08-01

    Medullary thyroid carcinoma (MTC) is a rare form of malignancy, having an intermediate prognosis. Controversies exist regarding the best surgical approach. The aim of the study was to analyze the outcome in a group of patients with MTC, diagnosed and followed up in a single care center. We performed a retrospective analysis of all the patients diagnosed with MTC in the Department of Endocrinology from the County Emergency Hospital Timisoara between 1992 and 2012. The study group included 19 patients, 6 men (31.6 %), mean age 41.2 ± 12.5 years (20-72 years). The preoperative diagnosis was based on the protocol for nodular thyroid disease. Total or near-total thyroidectomy was performed in 10 out of 16 patients who could be operated. Postoperative follow-up included repeated measurements of serum calcitonin and imaging investigations. Nine out of the total of 19 (47.3 %) patients had hereditary forms of MTC. Most of the cases (84.2 %) were submitted to surgery. The median duration of follow-up was 84 months. The pTNM staging indicated that the majority of the patients with hereditary MTC were diagnosed in an earlier stage. Disease remission was achieved in 7 cases (43.8 %). Four patients, all with sporadic forms, died. Survival rates at 1, 5 and 10 years were significantly higher (p = 0.048) in patients with hereditary MTC. An early diagnosis of MTC allows a better surgical approach and an improved survival rate. We support the general recommendation that modified radical neck dissection is not necessary for all the patients with MTC. PMID:27574350

  9. Optical scattering (TAOS) by tire debris particles: preliminary results

    Science.gov (United States)

    Crosta, Giovanni F.; Camatini, Marina C.; Zomer, Simeone; Holler, Stephen; Pan, Yongle; Bhaskara, Praveena; Muangchareon, Pongphisanu; Sung, Changmo; Cencetti, Simone; Regazzoni, Claudia

    2001-03-01

    Tire debris particles from low severity laboratory wear tests have been investigated by the TAOS optical scattering facility at Yale University. The incident wavelength is 532 nm. After the TAOS event some particle samples have been imaged by a scanning electron microscope and microanalyzed. The TAOS intensity patterns recorded within a solid angle in the backward sector have been processed by cluster analysis and compared with the patterns computed by a T-matrix code. Preliminary agreement has been found between TAOS data and the particle models (size, shape, refractive index). The purpose of the investigation is to obtain signatures of the material, based on its TAOS pattern.

  10. Warming Effect on Miriplatin-Lipiodol Suspension as a Chemotherapeutic Agent for Transarterial Chemoembolization for Hepatocellular Carcinoma: Preliminary Clinical Experience

    Energy Technology Data Exchange (ETDEWEB)

    Kora, Shinn-ichi; Urakawa, Hiroshi; Mitsufuji, Toshimichi; Osame, Akinobu [Fukuoka University, Department of Radiology, Faculty of Medicine (Japan); Higashihara, Hideyuki [Fukuoka University Chikushi Hospital, Department of Radiology (Japan); Yoshimitsu, Kengo, E-mail: kengo@fukuoka-u.ac.jp [Fukuoka University, Department of Radiology, Faculty of Medicine (Japan)

    2013-08-01

    PurposeTo retrospectively elucidate the preliminary clinical impact of warmed miriplatin-lipiodol suspension (MPT-LPD) when used as a chemotherapeutic agent for transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC).Materials and MethodsBetween June and December 2010, TACE was performed with MPT-LPD at room temperature (RT group), and after January 2011, TACE with MPT-LPD warmed to 40 Degree-Sign C was performed (W group). The intraarterial appearance of MPT-LPD immediately after injection through microcatheters at the second-order branches was compared between the two groups with a 5-point grading system. Local therapeutic effects of HCCs as assessed by follow-up computed tomography (CT) obtained 1-3 months after TACE were compared between the groups with a 4-point grading system (TE1-TE4). After April 2011, angiography-assisted CT was routinely performed at TACE, and HCCs that revealed apparent corona enhancement (CE) were retrospectively selected. The degree of concordance between CE and MPT-LPD accumulation as assessed by CT immediately after TACE was assessed with a 3-point grading scale.ResultsMPT-LPD therapy resulted in a smooth and continuous appearance in the W group (grades 1, 2, 3, 4, and 5 were, respectively, 1, 2, 11, 18, and 4) compared to the RT group (4, 0, 1, 2, and 0). The W group (TE1, TE2, TE3, and TE4 were 1, 9, 11, and 12) revealed better local therapeutic effects than the RT group (6, 3, 9, and 0) (p < 0.05). CE was found in 26 HCC nodules, and concordance between CE and MPT-LPD accumulation was observed in 66 % (grades 1, 2, and 3 were, respectively, 2, 8, and 19).ConclusionWarmed MPT-LPD flowed more smoothly within vascular lumen, passed through tumor sinusoid of HCC, and had better local therapeutic effects at short-term observation than MPT-LPD at room temperature.

  11. 78 FR 77651 - Seamless Refined Copper Pipe and Tube From Mexico: Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2013-12-24

    ... Refined Copper Pipe and Tube From Mexico: Final Results of Antidumping Duty New Shipper Review, 77 FR... International Trade Administration Seamless Refined Copper Pipe and Tube From Mexico: Preliminary Results of... are invited to comment on these preliminary results. \\1\\ See Seamless Refined Copper Pipe and...

  12. Computer-aided hepatic tumour ablation requirements and preliminary results

    CERN Document Server

    Voirin, D; Amavizca, M; Letoublon, C; Troccaz, J; Voirin, David; Payan, Yohan; Amavizca, Miriam; Letoublon, Christian; Troccaz, Jocelyne

    2002-01-01

    Surgical resection of hepatic tumours is not always possible, since it depends on different factors, among which their location inside the liver functional segments. Alternative techniques consist in local use of chemical or physical agents to destroy the tumour. Radio frequency and cryosurgical ablations are examples of such alternative techniques that may be performed percutaneously. This requires a precise localisation of the tumour placement during ablation. Computer-assisted surgery tools may be used in conjunction with these new ablation techniques to improve the therapeutic efficiency, whilst they benefit from minimal invasiveness. This paper introduces the principles of a system for computer-assisted hepatic tumour ablation and describes preliminary experiments focusing on data registration evaluation. To keep close to conventional protocols, we consider registration of pre-operative CT or MRI data to intra-operative echographic data.

  13. Preliminary Results on Lunar Interior Properties from the GRAIL Mission

    Science.gov (United States)

    Williams, James G.; Konopliv, Alexander S.; Asmar, Sami W.; Lemoine, H. Jay; Melosh, H. Jay; Neumann, Gregory A.; Phillips, Roger J.; Smith, David E.; Solomon, Sean C.; Watkins, Michael M.; Wieczorek, Mark A.; Zuber, Maria T.; Andrews-Hanna, Jeffrey C.; Head, James W.; Kiefer, Walter S.; Matsuyama, Isamu; McGovern, Patrick J.; Nimmo, Francis; Weber, Renee C.; Boggs, D. H.; Goossens, Sander J.; Kruizinga, Gerhard L.; Mazarico, Erwan; Park, Ryan S.; Yuan, Dah-Ning

    2013-01-01

    The Gravity Recovery and Interior Laboratory (GRAIL) mission has provided lunar gravity with unprecedented accuracy and resolution. GRAIL has produced a high-resolution map of the lunar gravity field while also determining tidal response. We present the latest gravity field solution and its preliminary implications for the Moon's interior structure, exploring properties such as the mean density, moment of inertia of the solid Moon, and tidal potential Love number k2. Lunar structure includes a thin crust, a deep mantle, a fluid core, and a suspected solid inner core. An accurate Love number mainly improves knowledge of the fluid core and deep mantle. In the future GRAIL will search for evidence of tidal dissipation and a solid inner core.

  14. 78 FR 34649 - Aluminum Extrusions From the People's Republic of China: Preliminary Results of Countervailing...

    Science.gov (United States)

    2013-06-10

    ..., 76 FR 30653 (May 26, 2011) (Order). \\3\\ See ``Decision Memorandum for Preliminary Results of the... International Trade Administration Aluminum Extrusions From the People's Republic of China: Preliminary Results...) is conducting an administrative review of the countervailing duty (CVD) order on aluminum...

  15. 75 FR 48310 - Purified Carboxymethylcellulose From the Netherlands; Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2010-08-10

    ...: Purified Carboxymethylcellulose from the Netherlands, 70 FR 28275 (May 17, 2005). We have not completed a... Netherlands; Preliminary Results of Antidumping Duty Administrative Review, 74 FR 24823 (May 26, 2009) at... Carboxymethylcellulose From the Netherlands; Preliminary Results of Antidumping Duty Administrative Review, 74 FR...

  16. Magnetization transfer imaging of normal and abnormal testis: preliminary results

    International Nuclear Information System (INIS)

    The aim was to determine the magnetization transfer ratio (MTR) of normal testes, possible variations with age and to assess the feasibility of MTR in characterizing various testicular lesions. Eighty-six men were included. A three-dimensional gradient-echo MT sequence was performed, with/without an on-resonance binomial prepulse. MTR was calculated as: (SIo-SIm)/(SIo) x 100 %, where SIm and SIo refers to signal intensities with and without the saturation pulse, respectively. Subjects were classified as: group 1, 20-39 years; group 2, 40-65 years; and group 3, older than 65 years of age. Analysis of variance (ANOVA) followed by the least significant difference test was used to assess variations of MTR with age. Comparison between the MTR of normal testis, malignant and benign testicular lesions was performed using independent-samples t testing. ANOVA revealed differences of MTR between age groups (F = 7.51, P = 0.001). Significant differences between groups 1, 2 (P = 0.011) and 1, 3 (P < 0.001) were found, but not between 2, 3 (P = 0.082). The MTR (in percent) of testicular carcinomas was 55.0 ± 3.2, significantly higher than that of benign lesions (50.3 ± 4.0, P = 0.02) and of normal testes (47.4 ± 2.2, P < 0.001). MTR of normal testes decreases with age. MTR might be helpful in the diagnostic work-up of testicular lesions. (orig.)

  17. Magnetization transfer imaging of normal and abnormal testis: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Tsili, Athina C.; Ntorkou, Alexandra; Maliakas, Vasilios; Argyropoulou, Maria I. [University of Ioannina, Department of Clinical Radiology, Medical School, Ioannina (Greece); Baltogiannis, Dimitrios; Sylakos, Anastasios; Sofikitis, Nikolaos [University of Ioannina, Department of Urology, Medical School, Ioannina (Greece); Stavrou, Sotirios [University of Ioannina, Department of Urology, Medical School, Ioannina (Greece); University Hospital of Ioannina, Leoforos S. Niarchou, Department of Urology, Ioannina (Greece); Astrakas, Loukas G. [University of Ioannina, Department of Medical Physics, Medical School, Ioannina (Greece)

    2016-03-15

    The aim was to determine the magnetization transfer ratio (MTR) of normal testes, possible variations with age and to assess the feasibility of MTR in characterizing various testicular lesions. Eighty-six men were included. A three-dimensional gradient-echo MT sequence was performed, with/without an on-resonance binomial prepulse. MTR was calculated as: (SIo-SIm)/(SIo) x 100 %, where SIm and SIo refers to signal intensities with and without the saturation pulse, respectively. Subjects were classified as: group 1, 20-39 years; group 2, 40-65 years; and group 3, older than 65 years of age. Analysis of variance (ANOVA) followed by the least significant difference test was used to assess variations of MTR with age. Comparison between the MTR of normal testis, malignant and benign testicular lesions was performed using independent-samples t testing. ANOVA revealed differences of MTR between age groups (F = 7.51, P = 0.001). Significant differences between groups 1, 2 (P = 0.011) and 1, 3 (P < 0.001) were found, but not between 2, 3 (P = 0.082). The MTR (in percent) of testicular carcinomas was 55.0 ± 3.2, significantly higher than that of benign lesions (50.3 ± 4.0, P = 0.02) and of normal testes (47.4 ± 2.2, P < 0.001). MTR of normal testes decreases with age. MTR might be helpful in the diagnostic work-up of testicular lesions. (orig.)

  18. Genesis Silicon Carbide Concentrator Target 60003 Preliminary Ellipsometry Mapping Results

    Science.gov (United States)

    Calaway, M. J.; Rodriquez, M. C.; Stansbery, E. K.

    2007-01-01

    The Genesis concentrator was custom designed to focus solar wind ions primarily for terrestrial isotopic analysis of O-17/O-16 and O-18/O-16 to +/-1%, N-15/N-14 to +/-1%, and secondarily to conduct elemental and isotopic analysis of Li, Be, and B. The circular 6.2 cm diameter concentrator target holder was comprised of four quadrants of highly pure semiconductor materials that included one amorphous diamond-like carbon, one C-13 diamond, and two silicon carbide (SiC). The amorphous diamond-like carbon quadrant was fractured upon impact at Utah Test and Training Range (UTTR), but the remaining three quadrants survived fully intact and all four quadrants hold an important collection of solar wind. The quadrants were removed from the target holder at NASA Johnso n Space Center Genesis Curation Laboratory in April 2005, and have been housed in stainless steel containers under continual nitrogen purge since time of disintegration. In preparation for allocation of a silicon carbide target for oxygen isotope analyses at UCLA, the two SiC targets were photographed for preliminary inspection of macro particle contamination from the hard non-nominal landing as well as characterized by spectroscopic ellipsometry to evaluate thin film contamination. This report is focused on Genesis SiC target sample number 60003.

  19. FDG-PET of autoimmune-related pancreatitis: preliminary results

    International Nuclear Information System (INIS)

    The purpose of this retrospective study was to elucidate the fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) findings in autoimmune-related pancreatitis (AIP), which is a reversible chronic pancreatitis with an autoimmune cause. The study group comprised six patients with clinically diagnosed AIP. After 370 MBq (10 mCi) of FDG had been injected intravenously, the abdomen and/or the whole body was scanned at 1 h post injection in all patients, and scanning was repeated at 2 h in four patients. PET findings were evaluated visually and/or semiquantitatively using the standardized uptake value (SUV). In four of the six patients, PET demonstrated intense uptake in the whole pancreas, which appeared swollen on computed tomography, and the accumulation increased with time in three patients. In one patient, intense focal uptake in the pancreatic head was observed, and the accumulation decreased over time. In the remaining patient, no abnormal accumulation in the pancreas was observed. Follow-up PET scanning after steroid therapy was performed in three patients, and intense FDG uptake was no longer observed. Our preliminary data show that AIP can cause intense FDG uptake in the pancreas. This fact, and the benign status of the condition, should be kept in mind when making a diagnosis with FDG-PET in patients with pancreatic disorders. (orig.)

  20. Preliminary Cluster Size and Efficiencies results of CMS RPC at GIF++

    CERN Document Server

    Gonzalez Blanco Gonzalez, Genoveva

    2016-01-01

    A brief description and first preliminary results of the Efficiencies and Cluster Size measurements of the CMS Resistive Plate Chambers, will be presented inside the Gamma Irradiation Facility GIF++ at CERN. Preliminary studies that sets the base performance measurements of CMS RPC for starting aging studies.

  1. Cosmetic result with radiations in lip carcinoma treatment

    International Nuclear Information System (INIS)

    The lip forms a complex sphinterian mechanism which is part of several functions: speaking, feeding, breathing and swallowing. Modern technical surgical of reconstruction exist, that conserve partially the anatomy and function of the lip, without getting the functional and a sthetic results of excellence. The radiotherapy gets results with intact skin and muscular innervation. (The author)

  2. Preliminary Results on Sediment Sorting Under Intense Bedload Transport

    Science.gov (United States)

    Hernandez Moreira, R. R.; Vautin, D.; Mathews, S. L.; Kuprenas, R.; Viparelli, E.

    2014-12-01

    Previous experiments show that parallel-laminated deposits are emplaced under upper plane bed regime by the migration of small-amplitude, long-wavelength bedforms. The present research focuses on how sediment is sorted under upper plane bed and sheet flow transport regimes, and whether parallel-lamination is inhibited during sheet flow transport. The problem of studying the sorting of sediment under so intense transport conditions is plagued by the uncertainties related to flow resistances and bedload transport rates. We simplify the problem by first running the experiments with uniform sediment, to establish a baseline that will aid in the design of the experiments with poorly sorted material. We are running experiments at the Hydraulics Laboratory of the Department of Civil and Environmental Engineering at the University of South Carolina in Columbia, in a unidirectional sediment-feed flume, 9 meters long by 0.2 meters wide, of which 7 meters are used as test section. During the experiments, water surface and bed elevations are periodically measured to characterize the global parameters of the flow, e.g. mean flow velocity and bed shear stress. When the flow and the sediment transport reach conditions of mobile bed equilibrium, bed elevation fluctuations are measured with ultrasonic transducer systems at six fixed locations. Channel bed aggradation is then induced by slowly raising the tail gate of the flume such that there is no change in transport regime, as confirmed by additional measurements of water surface and bed elevation and bed elevation fluctuations. Preliminary observations under upper plane bed regime show the formation of the small-amplitude and long-wavelength bedforms, as well as hints of parallel lamination in the deposits. In the near future we aim to achieve sheet flow transport conditions with both uniform and non-uniform grain size distributions to look at the internal structure of the emplaced deposit.

  3. Xanthogranulomatous cholecystitis mimicking gallbladder carcinoma with a false-positive result on fluorodeoxyglucose PET

    Institute of Scientific and Technical Information of China (English)

    Isamu Makino; Takahiro Yamaguchi; Nariatsu Sato; Toshiaki Yasui; Ichiro Kita

    2009-01-01

    Recently, several reports have demonstrated that fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) is useful in differentiating between benign and mal ignant lesions in the gallbladder. However, there is a limitation in the ability of FDG-PET to differentiate between inflammatory and malignant lesions. We herein present a case of xanthogranulomatous cholecystitis misdiagnosed as gallbladder carcinoma by ultrasonography and computed tomography. FDG-PET also showed increased activity. In this case, FDG-PET findings resulted in a false-positive for the diagnosis of gallbladder carcinoma.

  4. Elective brain irradiation in patients with small-cell carcinoma of the lung: preliminary report

    International Nuclear Information System (INIS)

    The brain is a common site of metastases in small-cell carcinoma of the lung. Prophylactic brain irradiation with doses of 4000-4500 rads in 3-4 weeks appears to decrease the occurrence of brain metastases although it does not prevent this completely. In a group of patients with small-cell carcinoma of the lung and without evidence of brain metastases, the authors review the site and extent of the primary, the methods of treatment, the techniques of brain irradiation, and the relapses rate in relation to the status of the primary and the rate of brain metastases in another group without prophylactic brain irradiation. They further attempt to investigate combined modalities of treatment which would prolong life and prevent neurological complications in the small number of long survivors with small-cell carcinoma of the lung. (Auth.)

  5. Microbial extremophiles from the 2008 Schirmacher Oasis Expedition: preliminary results

    Science.gov (United States)

    Hoover, Richard B.; Pikuta, Elena V.; Townsend, Alisa; Anthony, Joshua; Guisler, Melissa; McDaniel, Jasmine; Bej, Asim; Storrie-Lombardi, Michael

    2008-08-01

    Among the most interesting targets for Astrobiology research are the polar ice caps and the permafrost of Mars and the ice and liquid water bodies that may lie beneath the frozen crusts of comets, the icy moons of Jupiter (Europa, Io and Ganymede) and Saturn (Titan and Enceladus). The permanently ice-covered lakes of Antarctica, such as Lake Vostok and Lake Untersee, provide some of the best terrestrial analogues for these targets. The 2008 International Tawani Schirmacher Oasis/Lake Untersee Expeditions have been organized to conduct studies of novel microbial extremophiles and investigate the biodiversity of the glaciers and ice-covered lakes of Dronning Maud Land, East Antarctica. This paper describes the preliminary analysis of the anaerobic microbial extremophiles isolated from samples collected during the 2008 International Schirmacher Oasis Antarctica Reconnaissance Expedition. These samples showed great diversity of psychrophlic and psychrotolerant bacteria. Six new anaerobic strains have been isolated in pure cultures and partially characterized. Two of them (strains ARHSd-7G and ARHSd-9G) were isolated from a small tidal pool near the colony of African Penguins Spheniscus demersus. Strain ARHSd-7G was isolated on mineral anaerobic medium with 3 % NaCl, pH 7 and D-glucose, it has motile, vibrion shape cells, and is Gram variable. Strain ARHSd-9G grew on anaerobic, alkaline medium with pH 9 and 1 % NaCl at 3°C. The substrate was D-glucose supplemented with yeast extract (0.05 %). Cells of strain ARHSd-9G had morphology of straight or slightly curved elongated rods and demonstrated unusual optical effects under dark-field visible light microscopy. The cells were spore-forming and Gram positive. From the mat sample collected near Lake Zub, the new strain LZ-3 was isolated in pure culture at 3°C. Strain LZ-3 was anaerobic and grew on 0.5 % NaCl mineral medium with Dglucose as a substrate. The gram positive cells were spore-forming. They exhibited a

  6. Treatment results of pediatric nasopharyngeal carcinoma, NCI, Cairo University experience

    Directory of Open Access Journals (Sweden)

    Ehab M. Khalil

    2015-09-01

    Conclusion: Radio-chemotherapy management for pediatric NPC resulted in comparable treatment outcomes with tolerable late effects. Response adapted radio-chemotherapy regimens in addition to the potential use of IMRT should be recommended to decrease treatment related side effects. Prolonged OAP of RT ⩾ 50 days and low Hb level were encountered as adverse prognostic factors; findings that need further investigation.

  7. Relevance of intra operative radiotherapy in the treatment of uterine carcinoma - Lyon preliminary experience

    International Nuclear Information System (INIS)

    Aim: Retrospective analysis of Intra operative Radiotherapy (IORT) in recurrent uterine carcinoma (RUC) and prospective pilot study of IORT in advanced cervix cancer (ACC) with high risk of local failure. Patients-Treatments: (1) RUC: from 1988 to 1991, 34 patients with RUC have been treated. Primary cancer was: cervix uterus: 28, endometrium: six. Site of recurrence: centro pelvis: four, latero pelvis: 25, lombo aortic: five. Total gross resection was only possible in 12 patients. A dose of 15 to 22 Gy was given by IORT according to the residual tumour size. External beam irradiation was added in 16 patients; (2) ACC: January 1991 to November 1992, 20 patients were included in this pilot study, stage IIB: seven, stage III: 12, stage IV: 1. Preoperative retroperitoneal pelviscopy showed 13 pN1 patients and NMR imaging ten tumours of 6 cm or larger in diameter. Treatment started with concomitant pelvic irradiation (44 Gy) and one concomitant cycle of 5 Fu-CDDP, followed by a short course of high dose rate upper vagina brachytherapy (4Gy). Four weeks later a radical Wertheim operation was performed together with IORT on the lateral pelvis. Results: (1) RUC: overall survival (Kaplan Meier) at 4 years is 32% (±8). Local relapse in the field of IORT was observed in six patients. Grade 2-3 complications: six patients (radiation proctitis, neuritis, vertebral collapse, ureteral stenosis); (2) ACC: the median follow up is short (18 months). Four cases of pelvic relapse, no postoperative death. The first line radio chemotherapy was associated with two G3 early complications. Postoperative radiation complication was less than 10% G3. Discussion: promising results of IORT in RUC have been observed especially if no irradiation is given during the primary treatment. Good feasibility of the pilot study of IORT in ACC was also observed. It could be followed by a multicentric feasibility trial. (authors). 38 refs., 4 tabs., 1 fig

  8. Feasibility and early results of accelerated radiotherapy for head and neck carcinoma in the elderly

    OpenAIRE

    Allal, Abdelkarim Said; Maire, Daphne Isabel; Becker, Minerva; Dulguerov, Pavel

    2000-01-01

    Accelerated radiotherapy (RT) represents a promising method with which to improve the treatment outcome in patients with head and neck carcinoma. However, its applicability to elderly patients has not been well established. This study assessed treatment toxicities, patient compliance, and oncologic results in patients age >/= 70 years who were treated with an accelerated concomitant boost RT schedule.

  9. The Mount Logan (Yukon) Ice Cores: Preliminary Results

    Science.gov (United States)

    Fisher, D. A.

    2004-05-01

    Bourgeois, Mike Demuth, David Fisher, Roy Koerner,Chris Zdanowicz, James Zheng. University of Ottawa: Ian Clarke,Raphaelle Cardyn. National Institute of Polar Research (Japan): Kumiko Goto-Azuma University of New Hampshire: Cam Wake, Kaplan Yalcin. University of Maine: Karl Kreutz, Paul Mayewski, Erich Osterberg. Arctic Institute of North America: Gerald Holdsworth. University of Washington: Eric J. Steig, Summer B. Rupper. University of Copenhagen: Dorthe Dahl-Jensen. David Fisher is the presenter but many contributed to what is a joint preliminary offering.

  10. The Sunphotometer Airborne Validation Experiment 2012: Preliminary Results

    Science.gov (United States)

    Estellés, Victor; Marenco, Franco; Ryder, Claire L.; Campanelli, Monica; Expósito, Francisco; Solá, Yolanda; Segura, Sara; Marcos, Carlos; Toledano, Carlos; Berjón, Alberto; Guirado, Carmen; Claxton, Bernard; Todd, Martin

    2013-04-01

    to provide detailed vertically resolved aerosol measurements, in order to compare these to sunphotometer retrievals. Simultaneously, 4 different ground AERONET - Cimel sites were deployed in the Tenerife island, at different latitudes and altitudes for further investigation of spatial and vertical variability. Three of these sites also measured solar radiation components with CM21 pyranometers and CHP1 pirheliometers, for further research on radiative forcing of aerosols. One site was equipped with a Prede POM sun-sky radiometer for comparison with Cimel sunphotometer. On the other hand, for the FENNEC campaign another AERONET Cimel sunphotometer was deployed in Zouerate (Mauritania). The ideal conditions for such a comparison consisted of cloudless skies and high mineral aerosol burdens, brought by the Saharan outflow. Although these conditions were not reached in the Tenerife area during the scheduled field campaign, appropriate conditions were met in western Mauritania, over the AERONET Zouerate site. In this study, we perform a preliminary analysis of the columnar properties of aerosols in the Canary Islands and West Sahara areas during the FENNEC 2011 and FENNEC-SAVEX 2012 field campaigns, with an emphasis on the comparison between the size distributions retrieved from both AERONET and SKYRAD algorithms using the Zouerate Cimel site data. Validation of the vertical integrated aerosol size distributions will be also presented. References - M.Campanelli, V.Estelles, T. Smyth, T. Nakajima, M. Hashimoto, A.Lupi, C. Tomas, "Retrieval of aerosol radiative properties from sun-sky radiometers measurements of ESR network: comparison between the inversion codes Skyrad4.2.pack and the new Skyrad5.pack", European Aerosol Conference, 2011. - V. Estellés, M. Campanelli, M. P. Utrillas, F. Expósito, and J. A. Martínez-Lozano, "Comparison of AERONET and SKYRAD4.2 inversion products retrieved from a Cimel CE318 sunphotometer", Atmos. Meas. Tech. 5, 569—579, 2012.

  11. High-intensity focused ultrasound ablation for treatment of hepatocellular carcinoma and hypersplenism: preliminary study.

    Science.gov (United States)

    Zhu, Jing; Zhu, Hui; Mei, Zhechuan; Jin, Chengbing; Ran, Lifeng; Zhou, Kun; Yang, Wei; Zhang, Lian; She, Chaokun

    2013-10-01

    The purpose of this work was to preliminarily investigate the efficacy and safety of high-intensity focused ultrasound treatment of hepatocellular carcinoma and hypersplenism. Nine patients with hepatocellular carcinoma complicated by hypersplenism (5 male and 4 female; median age, 56 years; range, 51-66 years) were treated with ultrasound-guided high-intensity focused ultrasound. Complications were recorded. Laboratory examination and magnetic resonance imaging were used to evaluate the efficacy. After high-intensity focused ultrasound treatment, mean spleen ablation ± SD of 28.76% ± 6.1% was discovered; meanwhile, the white blood cell count, platelet count, and liver function of the patients were substantially improved during the follow-up period. In addition, symptoms such as epistaxis and gingival bleeding were ameliorated or even eliminated, and the quality of life was improved. Follow-up imaging showed a nonperfused volume in the spleen and an absence of a tumor blood supply at the treated lesions in the liver. For the first time to our knowledge, high-intensity focused ultrasound ablation was used to treat hepatocellular carcinoma complicated by hypersplenism. High-intensity focused ultrasound may be an effective and safe alternative for treatment of hepatocellular carcinoma complicated by hypersplenism, but further studies are necessary to clarify the mechanisms. PMID:24065267

  12. Multicentric ductal and lobular atypia and occult carcinoma in prophylactic subcutaneous mastectomies: a preliminary report.

    Science.gov (United States)

    Goin, J M; Kern, W H

    1979-02-01

    A report is made on 2 patients undergoing prophylactic subcutaneous mastectomy and reconstruction following treatment for carcinoma of the opposite breast. The dangers of augmenting, reducing, or correcting the shape of the remaining breast to match the reconstructed one are also examined. PMID:426453

  13. Differentiating hepatocellular carcinoma from angiomyolipoma of the liver with CT spectral imaging: A preliminary study

    International Nuclear Information System (INIS)

    Aim: To investigate the value of computed tomography (CT) spectral imaging in differentiating hepatocellular carcinoma (HCC) from angiomyolipoma (AML) during the arterial phase (AP) and portal venous phase (PP). Materials and method: Fifty-three patients underwent spectral CT during the AP and PP. Forty-five patients had 45 HCC and eight patients had eight AML. Iodine concentrations in the lesions were normalized to those of the aorta. The normalized iodine concentrations (NIC) and the lesion-normal parenchyma iodine concentration ratio (LNR) were calculated. The two-sample t-test was performed to compare quantitative parameters. Two readers qualitatively assessed lesion types on the basis of imaging features. Sensitivity and specificity were compared between the qualitative and quantitative studies. Results: NICs and LNRs in patients with HCC differed significantly from those in patients with AML: mean NICs were 0.25 ± 0.06 mg/ml versus 0.59 ± 0.03 mg/ml, respectively, during the AP and 0.52 ± 0.12 mg/ml versus 0.78 ± 0.03 mg/ml, respectively, during the PP. Mean LNRs were 2.97 ± 0.42 versus 5.85 ± 0.43, respectively, during the AP and 0.99 ± 0.17 versus 1.36 ± 0.05, respectively, during the PP. The NICs and LNRs for HCC were lower than those of AML during the AP and PP. The differences were significant (p < 0.05). The threshold NIC and LNR had high sensitivity and specificity in differentiating HCC from AML. Conclusion: CT spectral imaging with the quantitative analysis of iodine concentration may help increase the accuracy of differentiating HCC from AML

  14. In vitro study of UHMWPE/MWCNT – Preliminary results

    OpenAIRE

    Reis, J.; J. Potes; Capela e Silva, F.; Pereira, A.; S. Kanagaraj; Oliveira, M.; Simões, J.

    2008-01-01

    Reinforcement of ultra high molecular weight polyethylene (UHMWPE) by adding multiwalled carbon nanotubes (MWCNT) allows improvement of mechanical characteristics for biomedical applications. However, there is controversy when it comes to carbon nanotubes toxicity. Our objective was the in vitro study of UHMWPE/MWCNT. The results show good biocompatibility of the nanocomposite, comparable to results obtained by other authors.

  15. Correlation between PET/CT results and histological and immunohistochemical findings in breast carcinomas

    Directory of Open Access Journals (Sweden)

    Almir Galvão Vieira Bitencourt

    2014-04-01

    Full Text Available Objective To correlate the results of 18F-fluoro-2-deoxy-D-glucose (18F-FDG positron emission tomography/computed tomography (PET/CT performed with a specific protocol for assessment of breasts with histological/immunohistochemical findings in breast carcinoma patients. Materials and Methods Cross-sectional study with prospective data collection, where patients with biopsy-confirmed breast carcinomas were studied. The patients underwent PET/CT examination in prone position, with a specific protocol for assessment of breasts. PET/CT findings were compared with histological and immunohistochemical data. Results The authors identified 59 malignant breast lesions in 50 patients. The maximum diameter of the lesions ranged from 6 to 80 mm (mean: 32.2 mm. Invasive ductal carcinoma was the most common histological type (n = 47; 79.7%. At PET/CT, 53 (89.8% of the lesions demonstrated anomalous concentrations of 18F-FDG, with maximum SUV ranging from 0.8 to 23.1 (mean: 5.5. A statistically significant association was observed between higher values of maximum SUV and histological type, histological grade, molecular subtype, tumor diameter, mitotic index and Ki-67 expression. Conclusion PET/CT performed with specific protocol for assessment of breasts has demonstrated good sensitivity and was associated with relevant histological/immunohistochemical factors related to aggressiveness and prognosis of breast carcinomas.

  16. Value of three-dimensional reconstructions in pancreatic carcinoma using multidetector CT: Initial results

    Institute of Scientific and Technical Information of China (English)

    Miriam Klauβ; Max Sch(o)binger; Ivo Wolf; Jens Werner; Hans-Peter Meinzer; Hans-Ulrich Kauczor; Lars Grenacher

    2009-01-01

    AIM: To evaluate the use of three-dimensional imaging of pancreatic carcinoma using multidetector computed tomography (CT) in a prospective study. METHODS: Ten patients with suspected pancreatic tumors were examined prospectively using multidetector CT (Somatom Sensation 16, Siemens, Erlangen, Germany). The images were evaluated for the presence of a pancreatic carcinoma and invasion of the peripancreatic vessels and surrounding organs. Using the isotropic CT data sets, a three-dimensional image was created with automatic vascular analysis and semiautomatic segmentation of the organs and pancreatic tumor by a radiologist. The CT examinations and the three-dimensional images were presented to the surgeon directly before and during the patient's operation using the Medical Imaging Interaction Toolkit-based software "ReLiver". Immediately after surgery, the value of the two images was judged by the surgeon. The operation and the histological results served as the gold standard. RESULTS: Nine patients had a pancreatic carcinoma (all pT3), and one patient had a serous cystadenoma. One tumor infiltrated the superior mesenteric vein. The infiltration was correctly evaluated. All carcinomas were resectable. In comparison to the CT image with axial and coronal reconstructions, the three-dimensional image was judged by the surgeons as better for operation planning and consistently described as useful. CONCLUSION: A 3D-image of the pancreas represents an invaluable aid to the surgeon. However, the 3D-software must be further developed in order to be integrated into daily clinical routine.

  17. Uranium-liquid argon calorimetry: preliminary results from the DO tests

    International Nuclear Information System (INIS)

    The motivations for using uranium and liquid argon in sampling calorimetry are reviewed and the pros and cons of the technique are discussed. Preliminary results of the DO uranium-liquid argon test program are presented. 9 refs., 7 figs

  18. PRELIMINARY RESULTS OF INTRA CYTOPLASMIC SPERM INJECTION (ICSI) APPLIED ON RABBIT : A TECHNICAL NOTE.

    OpenAIRE

    Escribá, M.J.; García- Ximénez, F.

    1999-01-01

    Abstract not available. Escribá, M.; García- Ximénez, F. (1999). PRELIMINARY RESULTS OF INTRA CYTOPLASMIC SPERM INJECTION (ICSI) APPLIED ON RABBIT : A TECHNICAL NOTE. http://hdl.handle.net/10251/10364.

  19. 77 FR 66580 - Certain Preserved Mushrooms From India: Preliminary Results of Antidumping Duty Administrative...

    Science.gov (United States)

    2012-11-06

    ... India, 64 FR 8311 (February 19, 1999) (Mushroom Antidumping Duty Order), remains dispositive... International Trade Administration Certain Preserved Mushrooms From India: Preliminary Results of Antidumping... review of the antidumping duty order on certain preserved mushrooms (mushrooms) from India. The period...

  20. Event-Based Control over Networks: Some Research Questions and Preliminary Results

    OpenAIRE

    Henningsson, Toivo; Cervin, Anton

    2006-01-01

    The paper discusses some research questions related to event-based control over networks and presents preliminary results regarding event-based minimum-variance control of first-order systems with specified minimum inter-event times.

  1. Adenovirus mediated homozygous endometrial epithelial Pten deletion results in aggressive endometrial carcinoma

    International Nuclear Information System (INIS)

    Pten is the most frequently mutated gene in uterine endometriod carcinoma (UEC) and its precursor complex atypical hyperplasia (CAH). Because the mutation frequency is similar in CAH and UEC, Pten mutations are thought to occur relatively early in endometrial tumorigenesis. Previous work from our laboratory using the Pten+/- mouse model has demonstrated somatic inactivation of the wild type allele of Pten in both CAH and UEC. In the present study, we injected adenoviruses expressing Cre into the uterine lumen of adult Pten floxed mice in an attempt to somatically delete both alleles of Pten specifically in the endometrium. Our results demonstrate that biallelic inactivation of Pten results in an increased incidence of carcinoma as compared to the Pten+/- mouse model. In addition, the carcinomas were more aggressive with extension beyond the uterus into adjacent tissues and were associated with decreased expression of nuclear ERα as compared to associated CAH. Primary cultures of epithelial and stromal cells were prepared from uteri of Pten floxed mice and Pten was deleted in vitro using Cre expressing adenovirus. Pten deletion was evident in both the epithelial and stromal cells and the treatment of the primary cultures with estrogen had different effects on Akt activation as well as Cyclin D3 expression in the two purified components. This study demonstrates that somatic biallelic inactivation of Pten in endometrial epithelium in vivo results in an increased incidence and aggressiveness of endometrial carcinoma compared to mice carrying a germline deletion of one allele and provides an important in vivo and in vitro model system for understanding the genetic underpinnings of endometrial carcinoma.

  2. Adenovirus mediated homozygous endometrial epithelial Pten deletion results in aggressive endometrial carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, Ayesha; Ellenson, Lora Hedrick, E-mail: lora.ellenson@med.cornell.edu

    2011-07-01

    Pten is the most frequently mutated gene in uterine endometriod carcinoma (UEC) and its precursor complex atypical hyperplasia (CAH). Because the mutation frequency is similar in CAH and UEC, Pten mutations are thought to occur relatively early in endometrial tumorigenesis. Previous work from our laboratory using the Pten{sup +/-} mouse model has demonstrated somatic inactivation of the wild type allele of Pten in both CAH and UEC. In the present study, we injected adenoviruses expressing Cre into the uterine lumen of adult Pten floxed mice in an attempt to somatically delete both alleles of Pten specifically in the endometrium. Our results demonstrate that biallelic inactivation of Pten results in an increased incidence of carcinoma as compared to the Pten{sup +/-} mouse model. In addition, the carcinomas were more aggressive with extension beyond the uterus into adjacent tissues and were associated with decreased expression of nuclear ER{alpha} as compared to associated CAH. Primary cultures of epithelial and stromal cells were prepared from uteri of Pten floxed mice and Pten was deleted in vitro using Cre expressing adenovirus. Pten deletion was evident in both the epithelial and stromal cells and the treatment of the primary cultures with estrogen had different effects on Akt activation as well as Cyclin D3 expression in the two purified components. This study demonstrates that somatic biallelic inactivation of Pten in endometrial epithelium in vivo results in an increased incidence and aggressiveness of endometrial carcinoma compared to mice carrying a germline deletion of one allele and provides an important in vivo and in vitro model system for understanding the genetic underpinnings of endometrial carcinoma.

  3. Plasma technology for treating hazardous, radioactive, and mixed waste: Critical technology issues and preliminary results

    International Nuclear Information System (INIS)

    Plasma processing technology is currently being considered for the treatment of hazardous, radioactive, and mixed waste. The paper reviews the technology and proposes critical issues to be addressed in applying plasma to waste treatment. Preliminary results from a small scale plasma arcjet experiment with acetone were compared with predictions from ASPEN, a chemical equilibrium code. Preliminary results indicate that proper mixing and models describing the high temperature plasma chemical kinetics are needed to adequately predict the composition of the offgases

  4. Treatment results and prognostic factors of clear cell ovarian carcinomas and ovarian carcinomas with clear cell component

    Directory of Open Access Journals (Sweden)

    M. D. Ahmedova

    2014-07-01

    Full Text Available The most important prognostic factors for clear cell carcinoma (CCC are clinical and morphological signs and clinical stage of the disease. Analyses of 5-year survival in patients with I stage of CCC is 69 %, in II stage – 55 %, in III stage – 14 % and in IV stage – 4 % patients. We analyzed distant results of treatment of 71 patients with CCC and of 25 patients with mixed malignant ovaries neoplasm with obligatory clear cell component taking into consideration main clinical and morphological sings of disease. On the base of performed reseal we revealed that morphological structure of the tumors and stage of the disease exerted heist influence on the exponent of survival of the patients with clear CCC ovaries neoplasm. Besides, there is a correlation between exponent of patients’ survival and radicalized of surgery, character of tumor growth, differentiation degree, cell anaplasia and mitotic activity of tumor cells.

  5. Outcome of Patients With Metastatic Sarcomatoid Renal Cell Carcinoma: Results From the International Metastatic Renal Cell Carcinoma Database Consortium

    DEFF Research Database (Denmark)

    Kyriakopoulos, Christos E; Chittoria, Namita; Choueiri, Toni K;

    2015-01-01

    BACKGROUND: Sarcomatoid renal cell carcinoma is associated with poor prognosis. Data regarding outcome in the targeted therapy era are lacking. PATIENTS AND METHODS: Clinical, prognostic, and treatment parameters in metastatic renal cell carcinoma patients with and without sarcomatoid histology...... of sRCC is needed to develop alternative therapeutics....

  6. Preliminary results of standard quantitative analysis by ED-XRF

    International Nuclear Information System (INIS)

    A comparison between the results of elemental concentration proposed by XRS-FP software , using data obtained by EDXRF technique with those obtained by stoichiometric calculation was performed. For this purpose, five standard samples of known compounds were produced: two lead- oxide, magnesium chloride and iodine in controlled amounts. The compounds were subsequently mixed and compressed to form tablets. The samples were irradiated in three endpoints, according to an orientation. The measurements were performed at the Laboratory for Radiological UTFPR using X-123SDD the Amptek detector and X-ray tube with silver target from the same manufacturer. The operating conditions tube were 05μA current to a 40 kV voltage. Finally, the 15 spectra analyzed with the software to determine the concentration of chlorine, iodine and lead. Data from this analysis were compared with results expected in stoichiometric calculations. The data provided by the program, a convergence of results, indicating homogeneity of the samples was found. Compared to the stoichiometric calculation, a considerable discrepancy that may be the result of a misconfiguration or contamination of the sample was found. At the end, we created a proposal for continuation of the work using an auxiliary calculation should be developed in the next step

  7. Preliminary results of standard quantitative analysis by ED-XRF

    Energy Technology Data Exchange (ETDEWEB)

    Lara, Alessandro L. de; Franca, Alana C.; Neto, Manoel R.M.; Paschuk, Sergei A., E-mail: alellara@hotmail.com [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil). Dept. de Fisica; Denyak, Valeriy, E-mail: denyak@gmail.com [Instituto de Pesquisa Pele Pequeno Principe (IPPP), Curitiba, PR (Brazil)

    2013-07-01

    A comparison between the results of elemental concentration proposed by XRS-FP software , using data obtained by EDXRF technique with those obtained by stoichiometric calculation was performed. For this purpose, five standard samples of known compounds were produced: two lead- oxide, magnesium chloride and iodine in controlled amounts. The compounds were subsequently mixed and compressed to form tablets. The samples were irradiated in three endpoints, according to an orientation. The measurements were performed at the Laboratory for Radiological UTFPR using X-123SDD the Amptek detector and X-ray tube with silver target from the same manufacturer. The operating conditions tube were 05μA current to a 40 kV voltage. Finally, the 15 spectra analyzed with the software to determine the concentration of chlorine, iodine and lead. Data from this analysis were compared with results expected in stoichiometric calculations. The data provided by the program, a convergence of results, indicating homogeneity of the samples was found. Compared to the stoichiometric calculation, a considerable discrepancy that may be the result of a misconfiguration or contamination of the sample was found. At the end, we created a proposal for continuation of the work using an auxiliary calculation should be developed in the next step.

  8. Preliminary results of in vitro propagation of Guayule

    Science.gov (United States)

    Dastoor, M. N.; Schubert, W. W.; Petersen, G. R.

    1981-01-01

    Guayule, Parthenium argentatum Gray, was first established in tissue culture by Bonner and Arreguin (1950) as a means to study the effects of various chemicals and extracts on rubber production. The propagation of whole guayule plants from tissue culture, however, has not been accomplished. The reported investigation is concerned with such an objective. In an attempt to stimulate rubber production in Guayule, Yokoyama et al. (1977) sprayed juvenile plants with 2-(3,4-dichloro-phenoxy)triethylamine (TEA derivative). This treatment resulted in increased isoprenoid levels in the plant tissue. In the current investigation, experiments were conducted to study the effect of TEA derivative on in vitro cultures. It was found that a suppression of callus formation occurs at a 10 mg/L concentration of TEA derivative with a resultant increase of shoot formation. Lower and higher concentrations of TEA derivative promote callus formation.

  9. Magnetic field studies at Jupiter by Voyager 2 - Preliminary results

    Science.gov (United States)

    Ness, N. F.; Acuna, M. H.; Lepping, R. P.; Burlaga, L. F.; Behannon, K. W.; Neubauer, F. M.

    1979-01-01

    The Voyager 2 magnetic field experiment, for which the instrumentation is identical to that on Voyager 1, operated flawlessly throughout the second Jupiter encounter. The paper presents a brief overview of the results obtained to date on the Jovian magnetosphere, the bow shock, the magnetopause, and the extended magnetic tail. The results and the magnetic field geometry confirm the earlier conclusion from Voyager 1 that Jupiter has an enormous magnetic tail, approximately 300-400 Jupiter radii in diameter, trailing behind the planet with respect to the supersonic flow of the solar wind. Additional observations of the distortion of the inner magnetosphere by a concentrated plasma show a spatial merging of the equatorial magnetodisk current with the current sheet in the magnetic tail. Disturbances near Ganymede are discussed.

  10. Preliminary results on Alfven wave system in the TCABR tokamak

    International Nuclear Information System (INIS)

    A brief review of the Alfven Wave Excitation System (AWES) designed for the TCABR tokamak and the first experimental results on RF plasma heating are presented. One of four antenna modules has been completely installed in the vacuum chamber and the initial experiments were carried out in the low power regime using the four-phase RF generator. The main objectives were the antenna tuning according to the typical plasma parameters of TCABR and the evaluation of the antenna parasitic loading, as well as the calibration of the RF diagnostic tools in real discharge conditions. The first results have been obtained with standard diagnostics and with the RF signals measured using high sampling rate digital oscilloscopes. They showed that daily antenna cleaning and correct wave helicity excitation reduce significantly the parasitic loading and are crucial for efficient plasma coupling

  11. How Resilient Are Our Societies? Analyses, Models, and Preliminary Results

    OpenAIRE

    Florio, Vincenzo; Pajaziti, Arianit

    2015-01-01

    Traditional social organizations such as those for the management of healthcare and civil defence are the result of designs and realizations that matched well with an operational context considerably different from the one we are experiencing today: A simpler world, characterized by a greater amount of resources to match less users producing lower peaks of requests. The new context reveals all the fragility of our societies: unmanageability is just around the corner unless we do not complemen...

  12. Processed Vietnamese ginseng: Preliminary results in chemistry and biological activity

    OpenAIRE

    Le, Thi Hong Van; Lee, Seo Young; Kim, Tae Ryong; Kim, Jae Young; Kwon, Sung Won; NGUYEN, NGOC KHOI; Park, Jeong Hill; Nguyen, Minh Duc

    2013-01-01

    Background This study was carried out to investigate the effect of the steaming process on chemical constituents, free radical scavenging activity, and antiproliferative effect of Vietnamese ginseng. Methods Samples of powdered Vietnamese ginseng were steamed at 120°C for various times and their extracts were subjected to chemical and biological studies. Results Upon steaming, contents of polar ginsenosides, such as Rb1, Rc, Rd, Re, and Rg1, were rapidly decreased, whereas less polar ginsenos...

  13. Impediments to Marketing African Natural products From Ghana: Preliminary Results

    OpenAIRE

    Govindasamy, Ramu; Onyango, Benjamin M.; Puduri, Venkata S.; Simon, James E.; Asante-Dartey, Juliana; Arthur, Hanson; Diawuo, Bismarck; Acquaye, Dan

    2006-01-01

    For most of the African countries agriculture still remains the mainstay of the economies supplying both food and incomes via marketable surpluses. However, many odds against agriculture such low productivity, poor prices, and drought among others make it unsustainable. Results thus far show that such dependence has contributed little to neither economic development nor growth. Still many of its people living on and from agriculture remain poor, and are susceptible to hunger and malnutrition....

  14. Preliminary results from an indoor radon thoron survey in Hungary

    International Nuclear Information System (INIS)

    More than half of the radiation dose of natural origin comes from radon. However, according to some surveys in certain cases, the radiation dose originating from thoron may be considerable. Among the factors disturbing the measurement of radon, the presence of thoron may also influence the measured radon value, making the estimated radiation exposure imprecise. Thoron has previously been surveyed, mainly in Asia; however, recent surveys for some European locations have found that significant thoron concentrations also need to be considered. In this survey, several types of commercially available SSNTDs (solid-state nuclear track detectors) capable of measuring both radon and thoron were placed at the same time in 73 houses and 7 workplaces in Hungary with 3-month exposition periods. In order to measure thoron, the distance of the detector sets was fixed as 15-20 cm from the walls. The radon concentration was measured with five types of SSNTDs: NRPB, NRPB SSI, Raduet, DTPS and DRPS. The first four types had relatively good accordance (within ± 10 %), but the results of the DRPS detectors were considerably lower when compared with other detectors for radon concentrations over 100 Bq m-3. The thoron averages were provided by two different types of detectors: Raduet and DTPS. The difference between their average results was more than 30 % and was six times the maximum values. Therefore, the thoron measurement results were judged to be erroneous, and their measurement protocol should be clearly established for future work. (authors)

  15. Status and preliminary results of the ANAIS experiment at Canfranc

    International Nuclear Information System (INIS)

    ANAIS (Annual Modulation with NaI's) is an experiment planned to investigate seasonal modulation effects in the signal of galactic WIMPs using up to 107 kg of NaI(Tl) in the Canfranc Underground Laboratory (Spain). A prototype using one single crystal (10.7 kg) is being developed before the installation of the complete experiment; the first results presented here show an average background level of 1.2 counts/(keV kg day) from threshold (Ethr ∼ 4 keV) up to 10 keV

  16. Preliminary results of ITEC over an equatorial station

    International Nuclear Information System (INIS)

    Total electron content (TEC) was obtained from bottomside ionograms recorded at an equatorial station (Ouagadougou, 12.4 deg. N, 358.5 deg. E). Variability in TEC obtained in this way (ITEC) was investigated. Diurnal, seasonal and solar cycle effects were observed. Both absolute and relative variability were considered. The results obtained were compared with those of another equatorial station (Ghana, 5.63 deg. N, 359.8 deg. E) where the TEC was obtained by the Faraday rotation technique. The variations in variability at both stations follow the same trend. (author)

  17. ATOM PROBE STUDY OF TITANIUM BASE ALLOYS : PRELIMINARY RESULTS

    OpenAIRE

    Menand, A.; Chambreland, S.; Martin, C

    1986-01-01

    Two different titanium base alloys, Ti46 Al54 and Ti88.8 Cu2.3, Al8.9, have been studied by atom probe microanalysis. A precipitate of Ti2 Al was analysed in the binary alloys. Micro-analysis of Ti Cu Al alloy revealed the presence of Copper enriched zones. The study has also exhibited a penetration of Hydrogen in the samples, probably due to preparation technique. The results demonstrate the feasibility of studies on titanium base alloys by mean of atom probe.

  18. Development and preliminary results of radio frequency ion source

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Yahong, E-mail: xieyh@ipp.ac.cn; Hu, Chundong; Jiang, Caichao; Chen, Yuqian; Gu, Yumin; Su, Renxue; Xie, Yuanlai; Liu, Zhimin [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China)

    2016-02-15

    A radio frequency (RF) ion source was designed and developed for neutral beam injector. A RF driver test bed was used with a RF generator with maximum power of 25 kW with 1 MHz frequency and a matching box. In order to study the characteristic of RF plasma generation, the capacitance in the matching box was adjusted with different cases. The results show that lower capacitance will better the stability of the plasma with higher RF power. In the future, new RF coils and matching box will be developed for plasma generators with higher RF power of 50 kW.

  19. Interdisciplinary investigation of Boda clay-stone formation - preliminary results

    International Nuclear Information System (INIS)

    Document available in extended abstract form only. The aim of GEOCHEM Ltd.'s, partly EU-funded project, which started in 2008, was the comparison of the results of laboratory and field investigations, the assessment of their differences and the determination of scale in case of Boda clay-stone Formation (BCF - Mecsek Mts.). The formation has been researched as the potential host rock for the deep geological disposal of high level radioactive waste since 1999. Although the rock has been analyzed from numerous various aspects, its reservoir characteristics are still less known. As the achievement of the project's research and development activity, the reliable and fast measurement of petrophysical features became possible, as well as the comparison of results with the results of geophysical and geochemical investigations and their complex assessment. Petrophysical investigations of BCF have also been performed by the SzKFI, Geopard Ltd. and by the Department of Reservoir Engineering of Research Institute of Applied Chemistry, University of Miskolc (ME AFKI) that showed 0.04 - 3 % porosity and between 10-15- 10-21 m2 water permeability values. Similar, 10-15 and 10-19 m2 permeability values were produced by the in-situ packer tests of Mecsekerc Plc. The results clearly show that this rock is extremely tight and its petrophysical characteristics are hard to measure. An even more serious problem is to determine how laboratory results can be extended to the rock body itself, that is, can the scale dependence of data be determined. The project tries to realize this goal in three steps, by well logs in the given borehole, by CT and core scanning on the whole core and by mineralogical, geophysical, pore structure and permeability measurements performed on plugs prepared for laboratory investigations. Individual sub-tasks are performed as subcontractors by the Eoetvoes Lorand Geophysical Institute, the Research Institute of Applied Earth Sciences of the University of Miskolc

  20. Everolimus in Metastatic Renal Cell Carcinoma: Preliminary Experience from Chang Gung Memorial Hospital

    OpenAIRE

    Wen-Kuan Huang; Chuang-Chi Liaw; See-Tong Pang; Cheng-Keng Chuang; Yang-Jen Chiang; Chun-Te Wu; Ying-Hsu Chang; Hung-Ming Wang; Yung-Chang Lin; Jia-Juan Hsieh; Li-Ying Ou; Shih-I Tsai; Chih-Hsun Yang; Cheng-Ta Yang; John Wen-Cheng Chang

    2012-01-01

    Background: Everolimus has been approved for second-line treatment of patients with metastatic renal cell carcinoma (mRCC) after failure of sorafenib or sunitinib. The purpose of this retrospective study was to assess the efficacy and safety of everolimus in Taiwanese patients with mRCC.Methods: Between March 2009 and August 2011, 24 mRCC patients treated with everolimus were analyzed. Prior to everolimus, each patient had received therapy with at least one vascular endothelial growth factor ...

  1. Early carcinoma of the penis treated with radiation therapy: a preliminary report

    International Nuclear Information System (INIS)

    Four patients with stage 1 carcinoma of the penis were treated with radical external beam radiotherapy using individualized wax bolus. All patients are alive and doing well at the time of this report, 2 years after treatment. No patient had local recurrence and all had preservation of the organ and its function. Radiotherapy can be used as an alternative modality to surgery especially in the early stages of penile cancers. (author). 13 refs., 1 tab

  2. Design and preliminary results of the IMA plasma focus experiment

    International Nuclear Information System (INIS)

    The present paper describes the design, operation and characteristics of aton 1MA plasma focus device, which built in egypt at the plasma physics department, N.R.C., atomic energy authority. The main parts of the system are: the coaxial electrodes of mather type, the expansion chamber, the condenser bank of 75 kJ stored energy, the pressurized spark gap switches and Blumlein trigger system. Measurement of the breakdown voltage between plasma focus electrodes and discharge current, using half of the condenser bank, showed that, for Uc h = 32 kV, the discharge current was 0.5 Ma. In the discharge current and voltage traces a sharp drop in discharge current correspondingly to a sudden rise in voltage have been observed, which characterize the focus regime. Time structure of the x-ray emission measurements have been performed by means of scintillation detectors. by using a hydrogen gas the results showed that, the x-ray intensity is increased with increasing the hydrogen gas pressure. plasma sheath current density, J-Z distribution in axial direction during the acceleration phase of the discharge is studied, using a miniature Rogovsky coil. The results cleared that Jz is increased with the axial distance from breech to muzzle at different hydrogen gas pressures. 12 figs

  3. Simulation of diurnal thermal energy storage systems: Preliminary results

    Science.gov (United States)

    Katipamula, S.; Somasundaram, S.; Williams, H. R.

    1994-12-01

    This report describes the results of a simulation of thermal energy storage (TES) integrated with a simple-cycle gas turbine cogeneration system. Integrating TES with cogeneration can serve the electrical and thermal loads independently while firing all fuel in the gas turbine. The detailed engineering and economic feasibility of diurnal TES systems integrated with cogeneration systems has been described in two previous PNL reports. The objective of this study was to lay the ground work for optimization of the TES system designs using a simulation tool called TRNSYS (TRaNsient SYstem Simulation). TRNSYS is a transient simulation program with a sequential-modular structure developed at the Solar Energy Laboratory, University of Wisconsin-Madison. The two TES systems selected for the base-case simulations were: (1) a one-tank storage model to represent the oil/rock TES system; and (2) a two-tank storage model to represent the molten nitrate salt TES system. Results of the study clearly indicate that an engineering optimization of the TES system using TRNSYS is possible. The one-tank stratified oil/rock storage model described here is a good starting point for parametric studies of a TES system. Further developments to the TRNSYS library of available models (economizer, evaporator, gas turbine, etc.) are recommended so that the phase-change processes is accurately treated.

  4. Preliminary time-phased TWRS process model results

    International Nuclear Information System (INIS)

    This report documents the first phase of efforts to model the retrieval and processing of Hanford tank waste within the constraints of an assumed tank farm configuration. This time-phased approach simulates a first try at a retrieval sequence, the batching of waste through retrieval facilities, the batching of retrieved waste through enhanced sludge washing, the batching of liquids through pretreatment and low-level waste (LLW) vitrification, and the batching of pretreated solids through high-level waste (HLW) vitrification. The results reflect the outcome of an assumed retrieval sequence that has not been tailored with respect to accepted measures of performance. The batch data, composition variability, and final waste volume projects in this report should be regarded as tentative. Nevertheless, the results provide interesting insights into time-phased processing of the tank waste. Inspection of the composition variability, for example, suggests modifications to the retrieval sequence that will further improve the uniformity of feed to the vitrification facilities. This model will be a valuable tool for evaluating suggested retrieval sequences and establishing a time-phased processing baseline. An official recommendation on tank retrieval sequence will be made in September, 1995

  5. Preliminary time-phased TWRS process model results

    Energy Technology Data Exchange (ETDEWEB)

    Orme, R.M.

    1995-03-24

    This report documents the first phase of efforts to model the retrieval and processing of Hanford tank waste within the constraints of an assumed tank farm configuration. This time-phased approach simulates a first try at a retrieval sequence, the batching of waste through retrieval facilities, the batching of retrieved waste through enhanced sludge washing, the batching of liquids through pretreatment and low-level waste (LLW) vitrification, and the batching of pretreated solids through high-level waste (HLW) vitrification. The results reflect the outcome of an assumed retrieval sequence that has not been tailored with respect to accepted measures of performance. The batch data, composition variability, and final waste volume projects in this report should be regarded as tentative. Nevertheless, the results provide interesting insights into time-phased processing of the tank waste. Inspection of the composition variability, for example, suggests modifications to the retrieval sequence that will further improve the uniformity of feed to the vitrification facilities. This model will be a valuable tool for evaluating suggested retrieval sequences and establishing a time-phased processing baseline. An official recommendation on tank retrieval sequence will be made in September, 1995.

  6. Robot-assisted radical prostatectomy in Brazil: preliminary results

    Directory of Open Access Journals (Sweden)

    Jose Roberto Colombo Junior

    2009-12-01

    Full Text Available Purpose: To report the initial experience on robot-assisted radical prostatectomy in Brazil. Methods: From March 2008 to March 2009, a hundred patients were treated with robot-assisted radical prostatectomy. Patient’s demographic data, as well as perioperative results of the procedures, are described in this study. Rresults: Patients’ mean age and mean PSA were 58 years and 7.58 ng/ml, respectively. All procedures were performed through transperitoneal approach, with a mean bleeding of 480 mL and surgical time of 298 minutes. A surgical margin affected by cancer was present in 16% of the cases. There were four complications: bleeding requiring transfusion (two cases, rectal perforation corrected on the spot and inadequate functioning of the robot. There was no conversion to another access or obit occurrences in this caseload. Cconclusions: Robot-assisted prostatectomy is a reality in Brazil and the results herein presented demonstrate that this procedure can be safely performed. Long-term follow-up is still necessary to assess the oncological and functional outcomes.

  7. Simulating lightning into the RAMS model: implementation and preliminary results

    Directory of Open Access Journals (Sweden)

    S. Federico

    2014-05-01

    Full Text Available This paper shows the results of a tailored version of a previously published methodology, designed to simulate lightning activity, implemented into the Regional Atmospheric Modeling System (RAMS. The method gives the flash density at the resolution of the RAMS grid-scale allowing for a detailed analysis of the evolution of simulated lightning activity. The system is applied in detail to two case studies occurred over the Lazio Region, in Central Italy. Simulations are compared with the lightning activity detected by the LINET network. The cases refer to two thunderstorms of different intensity. Results show that the model predicts reasonably well both cases and that the lightning activity is well reproduced especially for the most intense case. However, there are errors in timing and positioning of the convection, whose magnitude depends on the case study, which mirrors in timing and positioning errors of the lightning distribution. To assess objectively the performance of the methodology, standard scores are presented for four additional case studies. Scores show the ability of the methodology to simulate the daily lightning activity for different spatial scales and for two different minimum thresholds of flash number density. The performance decreases at finer spatial scales and for higher thresholds. The comparison of simulated and observed lighting activity is an immediate and powerful tool to assess the model ability to reproduce the intensity and the evolution of the convection. This shows the importance of the use of computationally efficient lightning schemes, such as the one described in this paper, in forecast models.

  8. Speckle imaging with the MAMA detector: Preliminary results

    Science.gov (United States)

    Horch, E.; Heanue, J. F.; Morgan, J. S.; Timothy, J. G.

    1994-01-01

    We report on the first successful speckle imaging studies using the Stanford University speckle interferometry system, an instrument that uses a multianode microchannel array (MAMA) detector as the imaging device. The method of producing high-resolution images is based on the analysis of so-called 'near-axis' bispectral subplanes and follows the work of Lohmann et al. (1983). In order to improve the signal-to-noise ratio in the bispectrum, the frame-oversampling technique of Nakajima et al. (1989) is also employed. We present speckle imaging results of binary stars and other objects from V magnitude 5.5 to 11, and the quality of these images is studied. While the Stanford system is capable of good speckle imaging results, it is limited by the overall quantum efficiency of the current MAMA detector (which is due to the response of the photocathode at visible wavelengths and other detector properties) and by channel saturation of the microchannel plate. Both affect the signal-to-noise ratio of the power spectrum and bispectrum.

  9. Ramadan fasting: Evidence or expert opinion? Results of preliminary studies

    Directory of Open Access Journals (Sweden)

    1Maryam Kazemi

    2013-11-01

    Full Text Available Each year, over a billion Muslims fast worldwide during the month of Ramadan. Through this religious practice, not only will one have spiritual growth, but can improve his/her diet, which is of pivotal importance in this month. Conversely, the available evidence regarding the health benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many of them fast conceivably and their clinical condition is prone to deteriorate. This is due to the persistent gap between current expert knowledge and conclusive, strong evidence regarding the pathophysiologic and metabolic alterations by fasting, and the consensus that healthcare professionals should reach, in order to manage various patient groups during this month. In this review, we summarize the results of our initial studies regarding the effects of Ramadan fasting on some clinical conditions including alterations of body composition. We also go through the important clinical results of patients who have had previous history of cardiovascular disease, type 2 diabetes, asthma and renal colic. Our studies have presented some evidence in favor of Ramadan fasting and encourage those with mentioned diseases to consult their physicians and follow medical and scientific recommendations. We attempt to present some relevant evidence clarify future scopes in this area of study, and provide suggestions for future investigations.

  10. Ramadan fasting: Evidence or expert opinion? Results of preliminary studies

    Directory of Open Access Journals (Sweden)

    Maryam Kazemi

    2013-12-01

    Full Text Available Each year, over a billion Muslims fast worldwide during the month of Ramadan.  Through this religious practice, not only will one have spiritual growth, but can improve his/her diet, which is of pivotal importance in this month. Conversely, the available evidence regarding the health benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many of them fast conceivably and their clinical condition is prone to deteriorate. This is due to the persistent gap between current expert knowledge and conclusive, strong evidence regarding the pathophysiologic and metabolic alterations by fasting, and the consensus that healthcare professionals should reach, in order to manage various patient groups during this month. In this review, we summarize the results of our initial studies regarding the effects of Ramadan fasting on some clinical conditions including alterations of body composition. We also go through the important clinical results of patients who have had previous history of cardiovascular disease, type 2 diabetes, asthma and renal colic. Our studies have presented some evidence in favor of Ramadan fasting and encourage those with mentioned diseases to consult their physicians and follow medical and scientific recommendations. We attempt to present some relevant evidence clarify future scopes in this area of study, and provide suggestions for future investigations.

  11. Radiation pasteurization of poultry feed: Preliminary results of feeding tests

    International Nuclear Information System (INIS)

    Feed used to rear farm animals for human consumption has often been implicated as a vehicle for dissemination of microbial pathogens that can adversely affect both animals or birds, and humans. Radiation pasteurization of animal feed to improve its microbiological quality should reduce the incidence of feed-borne infection in the herd or flock. This would result in safer food for the consumer, and improved economic performance of the production unit. This latter benefit is particularly important because it would directly offset the cost of treating the feed. The likelihood of occurrence, as well as the magnitude, of any improved economic performance in the herd or flock consuming the irradiated feed must be determined experimentally. Accordingly, short term feeding tests were carried out to determine the effect of radiation pasteurization of poultry feed on growth performance of young chicks. The results suggest that radiation pasteurization of poultry feed may have a beneficial effect on the feed conversion efficiency of the birds consuming that feed. 10 refs, 8 tabs

  12. Preliminary Hydrogeologic Characterization Results from the Wallula Basalt Pilot Study

    Energy Technology Data Exchange (ETDEWEB)

    B.P. McGrail; E. C. Sullivan; F. A. Spane; D. H. Bacon; G. Hund; P. D. Thorne; C. J. Thompson; S. P. Reidel; F. S. Colwell

    2009-12-01

    The DOE's Big Sky Regional Carbon Sequestration Partnership has completed drilling the first continental flood basalt sequestration pilot borehole to a total depth (TD) of 4,110 feet on the Boise White Paper Mill property at Wallula, Washington. Site suitability was assessed prior to drilling by the 2007-2008 acquisition, processing and analysis of a four-mile, five-line three component seismic swath, which was processed as a single data-dense line. Analysis of the seismic survey data indicated a composite basalt formation thickness of {approx}8,000 feet and absence of major geologic structures (i.e., faults) along the line imaged by the seismic swath. Drilling of Wallula pilot borehole was initiated on January 13, 2009 and reached TD on April 6, 2009. Based on characterization results obtained during drilling, three basalt breccia zones were identified between the depth interval of 2,716 and 2,910 feet, as being suitable injection reservoir for a subsequent CO2 injection pilot study. The targeted injection reservoir lies stratigraphically below the massive Umtanum Member of the Grande Ronde Basalt, whose flow-interior section possesses regionally recognized low-permeability characteristics. The identified composite injection zone reservoir provides a unique and attractive opportunity to scientifically study the reservoir behavior of three inter-connected reservoir intervals below primary and secondary caprock confining zones. Drill cuttings, wireline geophysical logs, and 31one-inch diameter rotary sidewall cores provided geologic data for characterization of rock properties. XRF analyses of selected rock samples provided geochemical characterizations of the rocks and stratigraphic control for the basalt flows encountered by the Wallula pilot borehole. Based on the geochemical results, the pilot borehole was terminated in the Wapshilla Ridge 1 flow of the Grande Ronde Basalt Formation. Detailed hydrologic test characterizations of 12 basalt interflow

  13. Gastrointestinal transfer of neptunium (V) in newborn baboons: preliminary results

    International Nuclear Information System (INIS)

    To measure gastrointestinal neptunium absorption, baboons aged from 17 hours to 26 days were gavaged with an oral dose of 0.002 ug/kg of neptunium-239 nitrate. Absorption ranged from 3.71 to 0.113 per cent of the gavaged dose which was, 88 to 3 times higher than the values for adults. This range was reduced to 41 to 3 when doubtful results were discarded because of possible lung contamination. Absorption was expressed in terms of retention per animal at killing since collection of urine and faeces from neonates was not possible. For the same animals the skeleton/liver ratio of the neptunium burden rose continuously in the 26 dav-old baboon and reached twice the mean adult value

  14. Bioelectrical impedance analysis for bovine milk: Preliminary results

    Science.gov (United States)

    Bertemes-Filho, P.; Valicheski, R.; Pereira, R. M.; Paterno, A. S.

    2010-04-01

    This work reports the investigation and analysis of bovine milk quality by using biological impedance measurements using electrical impedance spectroscopy (EIS). The samples were distinguished by a first chemical analysis using Fourier transform midinfrared spectroscopy (FTIR) and flow citometry. A set of milk samples (100ml each) obtained from 17 different cows in lactation with and without mastitis were analyzed with the proposed technique using EIS. The samples were adulterated by adding distilled water and hydrogen peroxide in a controlled manner. FTIR spectroscopy and flow cytometry were performed, and impedance measurements were made in a frequency range from 500Hz up to 1MHz with an implemented EIS system. The system's phase shift was compensated by measuring saline solutions. It was possible to show that the results obtained with the Bioelectrical Impedance Analysis (BIA) technique may detect changes in the milk caused by mastitis and the presence of water and hydrogen peroxide in the bovine milk.

  15. SOME PRELIMINARY RESULTS FROM STUDY OF CRUSTAL DEFORMATION IN VIETNAM

    Institute of Scientific and Technical Information of China (English)

    Cao Dinh Trieu; Le Van Dung; Nguyen Huu Tuyen; Pham Nam Hung

    2003-01-01

    In this work, the authors present some results of strain monitoring within the territory of Vietnam from 1984 to 2001. Data analysis shows that (1) the Phu Lien area is tectonically stable with low strain rate, 1×10-6/a; (2) the Hoa Binh area has indication of tectonic instability with relatively high strain rate of the earth crust: absolute value of the strain reaching 100 × 10-6 , usual average strain amplitude of 60 × 10-6 , whereas the monthly average strain intensity varies in a range from 30× 10-6 to 50× 10-6 (3) there are clear indications of the strain state of the earth crust before occurrence of earthquakes of medium or higher magnitude. This is a very important indication in the research and short-term prediction of earthquakes, especially for the areas with low seismic stability like the NW of Vietnam.

  16. Preliminary Results of Testing of Flow Effects on Evaporator Scaling

    Energy Technology Data Exchange (ETDEWEB)

    Hu, M.Z.

    2002-02-15

    This investigation has focused on the effects of fluid flow on solids deposition from solutions that simulate the feed to the 2H evaporator at the Savannah River Site. Literature studies indicate that the fluid flow (or shear) affects particle-particle and particle-surface interactions and thus the phenomena of particle aggregation in solution and particle deposition (i.e., scale formation) onto solid surfaces. Experimental tests were conducted with two configurations: (1) using a rheometer to provide controlled shear conditions and (2) using controlled flow of reactive solution through samples of stainless steel tubing. All tests were conducted at 80 C and at high silicon and aluminum concentrations, 0.133 M each, in solutions containing 4 M sodium hydroxide and 1 A4 each of sodium nitrate and sodium nitrite. Two findings from these experiments are important for consideration in developing approaches for reducing or eliminating evaporator scaling problems: (1) The rheometer tests suggested that for the conditions studied, maximum solids deposition occurs at a moderate shear rate, approximately 12 s{sup -1}. That value is expected to be on the order of shear rates that will occur in various parts of the evaporator system; for instance, a 6 gal/min single-phase liquid flow through the 2-in. lift or gravity drain lines would result in a shear rate of approximately 16 s{sup -1}. These results imply that engineering approaches aimed at reducing deposits through increased mixing would need to generate shear near all surfaces significantly greater than 12 s{sup -1}. However, further testing is needed to set a target value for shear that is applicable to evaporator operation. This is because the measured trend is not statistically significant at the 95% confidence interval due to variability in the results. In addition, testing at higher temperatures and lower concentrations of aluminum and silicon would more accurately represent conditions in the evaporator. Without

  17. Preliminary results on scintigraphic evaluation of malignant external otitis

    International Nuclear Information System (INIS)

    Malignant external otitis (MEO) is a potentially fatal otitis occurring in diabetic and immunosuppressed patients, which may cause cranial nerve palsies and massive thrombophlebitis of the brain. We studied five diabetic patients with the clinical diagnosis of external otitis who were suspected of having MEO and one diabetic patient presumed cured from MEO. All of them underwent methylene diphosphonate, nanocolloid and gallium single-photon emission tomography studies with quantitative analysis on the basis of regions of interest and count profile curves. This combined assessment helped us to diagnose and follow-up soft tissue and temporal bone infection, especially in the case of transsphenoidal extension of the disease, since conventional radiology and computed tomography were of no particular help. On the basis of these results, we consider scintigraphic demonstration of skull base infection as a fourth criterion of MEO given that the classical Chandler's triad (diabetes, granuloma, and Pseudomonas aeruginosa) is not always present. (orig.)

  18. Bioenergy potentials from forestry to 2050. Preliminary results

    International Nuclear Information System (INIS)

    In this study a bottom-up scenario analysis of the global bioenergy production potential is carried out, with specific attention for the impact of underlying factors, existing outlook studies on demand and supply and gaps in the knowledge base that explain the large range in estimates. Key variables are the demand for industrial roundwood and fuelwood, plantation establishment rates and natural forest growth. Key uncertainties are the supply of wood from trees outside and the impact of sustainable forest management (SFM) of yields. Results show that the world is capable of meeting the future demand for industrial roundwood and fuelwood, without further deforestation. The total potential of bioenergy from surplus forest growth and residues is estimated at 27 to 140 EJy-1 in 2050

  19. Preliminary results from the MAMA detectors for the SOHO mission

    Science.gov (United States)

    Slater, David C.; Bergamini, Paolo; Bumala, Robert W.; Timothy, J. G.

    1993-01-01

    Multi-Anode Microchannel Array (MAMA) detector systems are being fabricated and tested for use in the Solar Ultraviolet Measurements of Emitted Radiation (SUMER) and the Ultraviolet Coronagraph Spectrometer (UVCS) instruments on the ESA/NASA Solar and Heliospheric Observatory (SOHO) mission. The SOHO MAMA detector systems have formats of 360 x 1024 pixels and pixel dimensions of 25 x 25 sq microns and are optimized for operation at Extreme Ultraviolet (EUV) wavelengths between 40 and 160 nm. In this paper we report on the initial results of measurements of the performance characteristics of the first flight-configuration detector system employing the new custom Application Specific Integrated Circuits (ASICs) which are designed to improve both the dynamic range and the uniformity of response. The performance characteristics of this detector system are compared with those of earlier breadboard systems employing discrete-component electronics circuits.

  20. Automated Optical Meteor Fluxes and Preliminary Results of Major Showers

    Science.gov (United States)

    Blaauw, R.; Campbell-Brown, M.; Cooke, W.; Kingery, A.; Weryk, R.; Gill, J.

    2014-01-01

    NASA's Meteoroid Environment Office (MEO) recently established a two-station system to calculate daily automated meteor fluxes in the millimeter-size-range for both single-station and double-station meteors. The cameras each consist of a 17 mm focal length Schneider lens (f/0.95) on a Watec 902H2 Ultimate CCD video camera, producing a 21.7x15.5 degree field of view. This configuration sees meteors down to a magnitude of +6. This paper outlines the concepts of the system, the hardware and software, and results of 3,000+ orbits from the first 18 months of operations. Video from the cameras are run through ASGARD (All Sky and Guided Automatic Real-time Detection), which performs the meteor detection/photometry, and invokes MILIG and MORB (Borovicka 1990) codes to determine the trajectory, speed, and orbit of the meteor. A subroutine in ASGARD allows for approximate shower identification in single-station detections. The ASGARD output is used in routines to calculate the flux. Before a flux can be calculated, a weather algorithm indicates if sky conditions are clear enough to calculate fluxes, at which point a limiting magnitude algorithm is employed. The limiting stellar magnitude is found using astrometry.net (Lang et al. 2012) to identify stars and translated to the corresponding shower and sporadic limiting meteor magnitude. It is found every 10 minutes and is able to react to quickly changing sky conditions. The extensive testing of these results on the Geminids and Eta Aquariids is shown. The flux involves dividing the number of meteors by the collecting area of the system, over the time interval for which that collecting area is valid. The flux algorithm employed here differs from others currently in use in that it does not make the gross oversimplication of choosing a single height to calculate the collection area of the system. In the MEO system, the volume is broken up into a set of height intervals, with the collecting areas determined by the position of the

  1. Results of radiation therapy in carcinomas of the floor of the mouth

    International Nuclear Information System (INIS)

    This report is chiefly based on the results achieved with radiation therapy alone in a group of patients suffering from floor-of-the-mouth carcinomas which, at an advanced stage (T3 and T4), are suggestive of a particularly unfavourable patient outcome in no less than 85% of the cases. In addition to results of treatment recorded at this clinic, a general survey is given on the various regimens currently used for radiotherapeutic procedures. (orig.)

  2. 3D inversion of lunar gravity data and preliminary results

    Science.gov (United States)

    Liang, Q.; Chen, C.; Li, Y.

    2010-12-01

    Gravity anomaly tells how the subsurface density varies or where the mass concentrations are located at. Inversion of gravity data gives a way to directly recover the density distributions. It has been demonstrated that the inversion is capable of retrieving density structures in resources exploration on the Earth. With increasing interests in interior structures of the Moon, scientists have obtained its gravity field with improved resolution on the lunar far side. We may thus utilize the inverse method to recover the lunar density structures beneath mascon basins or the density inhomogeneities in the crust and mantle. However, if considering the spherical gravity data in global scale, there are limitations in the previous inversion because the methods were based on the Cartesian coordinates system. In order to solve the problems, we developed a new 3D inverse method with three aspects involved: 1) A new model objective function adaptive to spherical coordinate system was established in the light of the Backus-Gilbert model appraisal theory. 2) A depth weighting function in inversion was also developed to approximately compensate for the kernel’s natural decay in potential field. And, 3) Non-uniqueness was suppressed by using model constraints and Tikhonov regularization tool. With the above developments and techniques, our method can quantitatively interpret the spherical gravity data. We firstly performed the inversion of synthetic data and confirmed that the locations of anomaly bodies were well defined, and then applied this method to the Bouguer gravity anomaly of the Moon which has been previously calculated based on the Chang'E-1 topography data and the SELENE gravity field model. Results showed that, on the one hand, the positive density anomalies beneath the mascon basins concentrated at the depth of 20-50km. Their residual densities are larger than 0.3g/cm^3 close to the density difference between lunar mantle and crust. Density structures along radial

  3. The ABC Schizophrenia Study: a preliminary overview of the results.

    Science.gov (United States)

    Häfner, H; Maurer, K; Löffler, W; an der Heiden, W; Munk-Jørgensen, P; Hambrecht, M; Riecher-Rössler, A

    1998-08-01

    The ABC Schizophrenia Study, a large-scale epidemiological and neurobiological research project commenced in 1987, initially pursued two aims: (1) to elucidate the possible causes of the sex difference in age at first admission for schizophrenia and (2) to analyse the early course of the disorder from onset until first contact and its implications for further course and outcome. First, transnational case-register data (for Denmark and Germany) were compared, second, a population-based sample of first-episode cases of schizophrenia (n = 232) were selected and third, the results obtained were compared with data from the WHO Determinants of Outcome Study by using a systematic methodology. A consistent result was a 3-4 years higher age of onset for women by any definition of onset, which was not explainable by social variables, such as differences in the male-female societal roles. A sensitivity-reducing effect of oestrogen on central D2 receptors was identified as the underlying neurobiological mechanism in animal experiments. Applicability to humans with schizophrenia was established in a controlled clinical study. A comparison of familial and sporadic cases showed that in cases with a high genetic load, the sex difference in age of onset disappeared due to a clearly reduced age of onset in women, whereas in sporadic cases it increased. To analyse early course retrospectively, a semistructured interview, IRAOS, was developed. The early stages of the disorder were reconstructed in comparison with age- and sex-matched controls from the same population of origin. The initial signs consisted mainly of negative and affective symptoms, which accumulated exponentially until the first episode, as did the later emerging positive symptoms. Social disability appeared 2-4 years before first admission on average. In early-onset cases, social course and outcome, studied prospectively over 5 years, was determined by the level of social development at onset through social stagnation

  4. Radiation therapy for macular degeneration: technical considerations and preliminary results

    International Nuclear Information System (INIS)

    Purpose: This study was undertaken to assess the toxicity and possible benefits from the administration of low-dose external-beam irradiation for Age-Related Macular Degeneration (ARMD). The premise of the treatment is that radiation induces regression and/or promotes inactivation of the subretinal neo-vasculature, resulting in reabsorption of fluid and blood thus reducing the risk for further leakage or bleeding, as well as subretinal fibrosis. Clinically, the beneficial effect could be translated into stabilization of visual acuity and prevention of progression of the wet type of ARMD with the possibility for some visual improvement. Methods and Materials: Allegheny University Hospitals, Hahnemann, Department of Radiation Oncology, treated 278 patients prospectively beginning in January 1995 with low-dose irradiation for wet-type macular degeneration. Two hundred forty-nine patients were treated with a total dose of 14.40 Gy in eight fractions of 1.80 Gy over 10-13 elapsed days, and 27 patients with 20 Gy at 2 Gy per fraction over 12-15 days. The first two patients were treated to a total dose of 10.00 Gy in five fractions of 2.00 Gy. Patients were evaluated at 2-3 weeks and 2-3 months. A percentage (36.7%) of the patients had previously received laser treatments in the study eye, 21.9% once, 5% twice, 9.7% three or more. Subjective visual acuity and toxicity data was collected on all patients. Results: At 2-3 weeks after treatment 195 patients (70%) retained their visual acuity without change, 68 patients (24.5%) stated they had improved vision, and 15 patients (4.8%) stated their vision continued to decrease. Two to 3 months after treatment, 183 patients (65.8%) had no change in their vision. 75 patients (27%) patients had an improvement in their vision, and 20 patients (7.2%) had a decrease in visual acuity. Transient acute reactions occurred in 14 of the 278 patients treated. Conclusion: Our observations in this group of 278 patients support the conclusion

  5. Magnetic field studies at jupiter by voyager 2: preliminary results.

    Science.gov (United States)

    Ness, N F; Acuna, M H; Lepping, R P; Burlaga, L F; Behannon, K W; Neubauer, F M

    1979-11-23

    Data from the Goddard Space Flight Center magnetometers on Voyager 2 have yielded on inbound trajectory observations of multiple crossings of the bow shock and magnetosphere near the Jupiter-sun line at radial distances of 99 to 66 Jupiter radii (RJ) and 72 to 62 RJ, respectively. While outbound at a local hour angle of 0300, these distances increase appreciably so that at the time of writing only the magnetopause has been observed between 160 and 185 RJ. These results and the magnetic field geometry confirm the earlier conclusion from Voyager I studies that Jupiter has an enormous magnetic tail, approximately 300 to 400 RJ in diameter, trailing behind the planet with respect to the supersonic flow of the solar wind. Addi- tional observations of the distortion of the inner magnetosphere by a concentrated plasma show a spatial merging of the equatorial magnetodisk current with the cur- rent sheet in the magnetic tail. The spacecraft passed within 62,000 kilometers of Ganymede (radius = 2,635 kilometers) and observed characteristic fluctuations in- terpreted tentatively as being due to disturbances arising from the interaction of the Jovian magnetosphere with Ganymede. PMID:17733916

  6. Preliminary results from the heavy ions in space experiment

    Science.gov (United States)

    Adams, James H., Jr.; Beahm, Lorraine P.; Tylka, Allan J.

    1992-01-01

    The Heavy Ions In Space (HIIS) experiment has two primary objectives: (1) to measure the elemental composition of ultraheavy galactic cosmic rays, beginning in the tin-barium region of the periodic table; and (2) to study heavy ions which arrive at LDEF below the geomagnetic cutoff, either because they are not fully stripped of electrons or because their source is within the magnetosphere. Both of these objectives have practical as well as astrophysical consequences. In particular, the high atomic number of the ultraheavy galactic cosmic rays puts them among the most intensely ionizing particles in Nature. They are therefore capable of upsetting electronic components normally considered immune to such effects. The below cutoff heavy ions are intensely ionizing because of their low velocity. They can be a significant source of microelectronic anomalies in low inclination orbits, where Earth's magnetic field protects satellites from most particles from interplanetary space. The HIIS results will lead to significantly improved estimates of the intensely ionizing radiation environment.

  7. Eight Pulse Performance of DARHT Axis II - Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Schulze, Martin E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-12-08

    The DARHT-II accelerator produces a 1.65-kA, 17-MeV beam in a 1600-ns pulse. Standard operation of the DARHT Axis II accelerator involves extracting four short pulses from the 1.6 us long macro-pulse produced by the LIA. The four short pulses are extracted using a fast kicker in combination with a quadrupole septum magnet and then transported for several meters to a high-Z material target for conversion to x-rays for radiography. The ability of the DARHT Axis 2 kicker to produce more than the standard four pulse format has been previously demonstrated. This capability was developed to study potential risks associated with beam transport during an initial commissioning phase at low energy (8 MeV) and low current (1.0 kA).The ability of the kicker to deliver more than four pulses to the target has been realized for many years. This note describes the initial results demonstrating this capability.

  8. Leaching in the material balance of peatlands - preliminary results

    International Nuclear Information System (INIS)

    The hydrology and hydrochemistry of Lakkasuo (Orivesi, central Finland) was studied for a 12 month period (Sep. 1991 - Aug. 1992). Results from four monitored catchments in Lakkasuo are presented. The catchments represent a bog and a fen, both in the natural stage and as drained for forestry 30 years ago. In the relatively wet study period (runoff 414 mm for the undrained bog), the catchments released 8.0-16.6 g/m2 of organic carbon (mainly dissolved) into runoff waters. All the catchments retained total N and sulfate provided by deposition or groundwater very effectively (65-80 % and 52-72 %, respectively); undrained catchments retained also total P. The net output rates of all the elements except H+ were greater from the drained catchments compared with the undrained ones. The leaching rates of Mg and Ca from the drained catchments were greater compared with the pool of these elements in the surface peat, whereas the K pool is more effectively retained and added to by deposition

  9. Preliminary results on isotopic methods for the control of wines

    International Nuclear Information System (INIS)

    Full text: Isotopic methods have shown to be a major tool for checking the compliance of food products and beverages with national and international regulations. This paper presents some results on isotopic methods for control of wines. We developed a method for determining 13C/12C and 18O/16O isotope ratios in wine's ethanol and water. These ratios are significantly influenced by geo-climatic conditions of the origin region of wine, the type of plant (species or subspecies), and the year of harvest. The determination of 13C/12C ratio of wine ethanol was performed in three steps: (I) 500 ml of a wine sample was distilled at constant reflux ratio, (10). The distillate was collected with an ethanol content of about 93 % (mass), without significant isotope fractionation; (II) The ethanol was converted into CO2 by combustion in excess of oxygen; (III) The carbon isotope ratio of CO2 was analyzed using the isotope ratio mass spectrometry (IRMS). The 18O/16O ratio of the wine water was determined by IRMS using CO2 obtained after equilibration of wine with carbon dioxide. We developed this method in order to get a data bank of isotope ratios for authentic samples of wine as well as for the routine control of many marketed wines. (authors)

  10. Light propagation in inhomogeneous universes. I. Methodology and preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Premadi, Premana; Matzner, Richard [Center for Relativity and Department of Physics, University of Texas, Austin, Texas78712 (United States)] Martel, Hugo [Department of Astronomy, University of Texas, Austin, Texas 78712 (United States)] Matzner, Richard [Orson Anderson Scholar, Los Alamos National Laboratory, 1996--1997 (United States)

    1998-01-01

    We describe a numerical algorithm that simulates the propagation of light in inhomogeneous universes. This algorithm computes the trajectories of light rays between the observer, located at redshift z=0, and distant sources located at high redshift using the multiple lens plane method. The deformation and deflection of light beams as they interact with each lens plane are computed using the filled-beam approximation. We use a particle-particle/particle-mesh (P{sup 3}M) N-body numerical code to simulate the formation of large-scale structure in the universe. We extend the length resolution of the simulations to sub-megaparsec scales by using a Monte Carlo method for locating galaxies inside the computational volume according to the underlying distribution of background matter. The observed galaxy two-point correlation function is reproduced. This algorithm constitutes a major improvement over previous methods, which either neglected the presence of large-scale structure, neglected the presence of galaxies, neglected the contribution of distant matter (matter located far from the beam), or used the Zeldovich approximation for simulating the formation of large-scale structure. In addition, we take into account the observed morphology-density relation when assigning morphological types to galaxies, something that was ignored in all previous studies. To test this algorithm, we perform 1981 simulations for three different cosmological models: an Einstein-de Sitter model with density parameter {Omega}{sub 0}=1, an open model with {Omega}{sub 0}=0.2, and a flat, low-density model with {Omega}{sub 0}=0.2 and a cosmological constant of {lambda}{sub 0}=0.8. In all models, the initial density fluctuations correspond to a cold dark matter power spectrum normalized to {ital COBE}. In each simulation, we compute the shear and magnification resulting from the presence of inhomogeneities. Our results are the following: (1) The magnification is totally dominated by the convergence

  11. Preliminary results on noncollocated torque control of space robot actuators

    Science.gov (United States)

    Tilley, Scott W.; Francis, Colin M.; Emerick, Ken; Hollars, Michael G.

    1989-01-01

    In the Space Station era, more operations will be performed robotically in space in the areas of servicing, assembly, and experiment tending among others. These robots may have various sets of requirements for accuracy, speed, and force generation, but there will be design constraints such as size, mass, and power dissipation limits. For actuation, a leading motor candidate is a dc brushless type, and there are numerous potential drive trains each with its own advantages and disadvantages. This experiment uses a harmonic drive and addresses some inherent limitations, namely its backdriveability and low frequency structural resonances. These effects are controlled and diminished by instrumenting the actuator system with a torque transducer on the output shaft. This noncollocated loop is closed to ensure that the commanded torque is accurately delivered to the manipulator link. The actuator system is modelled and its essential parameters identified. The nonlinear model for simulations will include inertias, gearing, stiction, flexibility, and the effects of output load variations. A linear model is extracted and used for designing the noncollocated torque and position feedback loops. These loops are simulated with the structural frequency encountered in the testbed system. Simulation results are given for various commands in position. The use of torque feedback is demonstrated to yield superior performance in settling time and positioning accuracy. An experimental setup being finished consists of a bench mounted motor and harmonic drive actuator system. A torque transducer and two position encoders, each with sufficient resolution and bandwidth, will provide sensory information. Parameters of the physical system are being identified and matched to analytical predictions. Initial feedback control laws will be incorporated in the bench test equipment and various experiments run to validate the designs. The status of these experiments is given.

  12. Thermal plasma treatment of cell-phone waste : preliminary result

    Energy Technology Data Exchange (ETDEWEB)

    Ruj, B. [Central Mechanical Engineering Research Inst., Durgapur (India). Thermal Engineering Group; Chang, J.S.; Li, O.L. [McMaster Univ., Hamilton, ON (Canada). Dept. of Engineering Physics; Pietsch, G. [RWTH Aachen Univ., Aachen (Germany)

    2010-07-01

    The cell phone is an indispensable service facilitator, however, the disposal and recycling of cell phones is a major problem. While the potential life span of a mobile phone, excluding batteries, is over 10 years, most of the users upgrade their phones approximately four times during this period. Cell phone waste is significantly more hazardous than many other municipal wastes as it contains thousands of components made of toxic chemicals and metals like lead, cadmium, chromium, mercury, polyvinyl chlorides (PVC), brominated flame retardants, beryllium, antimony and phthalates. Cell phones also use many expensive rare metals. Since cell phones are made up of plastics, metals, ceramics, and trace other substances, primitive recycling or disposal of cell phone waste to landfills and incinerators creates irreversible environmental damage by polluting water and soil, and contaminating air. In order to minimize releases into the environment and threat to human health, the disposal of cell phones needs to be managed in an environmentally friendly way. This paper discussed a safer method of reducing the generation of syngas and hydrocarbons and metal recovery through the treatment of cell phone wastes by a thermal plasma. The presentation discussed the experiment, with particular reference to sample preparation; experimental set-up; and results four samples with different experimental conditions. It was concluded that the plasma treatment of cell phone waste in reduced condition generates gaseous components such as hydrogen, carbon monoxide, and hydrocarbons which are combustible. Therefore, this system is an energy recovery system that contributes to resource conservation and reduction of climate change gases. 5 refs., 2 tabs., 2 figs.

  13. The HCV Synthesis Project: Scope, methodology, and preliminary results

    Directory of Open Access Journals (Sweden)

    Scheinmann Roberta

    2008-09-01

    Full Text Available Abstract Background The hepatitis C virus (HCV is hyper-endemic in injecting drug users. There is also excess HCV among non-injection drug users who smoke, snort, or sniff heroin, cocaine, crack, or methamphetamine. Methods To summarize the research literature on HCV in drug users and identify gaps in knowledge, we conducted a synthesis of the relevant research carried out between 1989 and 2006. Using rigorous search methods, we identified and extracted data from published and unpublished reports of HCV among drug users. We designed a quality assurance system to ensure accuracy and consistency in all phases of the project. We also created a set of items to assess study design quality in each of the reports we included. Results We identified 629 reports containing HCV prevalence rates, incidence rates and/or genotype distribution among injecting or non-injecting drug user populations published between January 1989 and December 2006. The majority of reports were from Western Europe (41%, North America (26%, Asia (11% and Australia/New Zealand (10%. We also identified reports from Eastern Europe, South America, the Middle East, and the Caribbean. The number of publications reporting HCV rates in drug users increased dramatically between 1989 and 2006 to 27–52 reports per year after 1998. Conclusion The data collection and quality assurance phases of the HCV Synthesis Project have been completed. Recommendations for future research on HCV in drug users have come out of our data collection phase. Future research reports can enhance their contributions to our understanding of HCV etiology by clearly defining their drug user participants with respect to type of drug and route of administration. Further, the use of standard reporting methods for risk factors would enable data to be combined across a larger set of studies; this is especially important for HCV seroconversion studies which suffer from small sample sizes and low power to examine risk

  14. Flight Test 4 Preliminary Results: NASA Ames SSI

    Science.gov (United States)

    Isaacson, Doug; Gong, Chester; Reardon, Scott; Santiago, Confesor

    2016-01-01

    Realization of the expected proliferation of Unmanned Aircraft System (UAS) operations in the National Airspace System (NAS) depends on the development and validation of performance standards for UAS Detect and Avoid (DAA) Systems. The RTCA Special Committee 228 is charged with leading the development of draft Minimum Operational Performance Standards (MOPS) for UAS DAA Systems. NASA, as a participating member of RTCA SC-228 is committed to supporting the development and validation of draft requirements as well as the safety substantiation and end-to-end assessment of DAA system performance. The Unmanned Aircraft System (UAS) Integration into the National Airspace System (NAS) Project conducted flight test program, referred to as Flight Test 4, at Armstrong Flight Research Center from April -June 2016. Part of the test flights were dedicated to the NASA Ames-developed Detect and Avoid (DAA) System referred to as JADEM (Java Architecture for DAA Extensibility and Modeling). The encounter scenarios, which involved NASA's Ikhana UAS and a manned intruder aircraft, were designed to collect data on DAA system performance in real-world conditions and uncertainties with four different surveillance sensor systems. Flight test 4 has four objectives: (1) validate DAA requirements in stressing cases that drive MOPS requirements, including: high-speed cooperative intruder, low-speed non-cooperative intruder, high vertical closure rate encounter, and Mode CS-only intruder (i.e. without ADS-B), (2) validate TCASDAA alerting and guidance interoperability concept in the presence of realistic sensor, tracking and navigational errors and in multiple-intruder encounters against both cooperative and non-cooperative intruders, (3) validate Well Clear Recovery guidance in the presence of realistic sensor, tracking and navigational errors, and (4) validate DAA alerting and guidance requirements in the presence of realistic sensor, tracking and navigational errors. The results will be

  15. The Hyperspectral Thermal Emission Spectrometer (HyTES): Preliminary Results

    Science.gov (United States)

    Hook, Simon; Johnson, William R.; Eng, Bjorn T.; Gunapala, Sarah D.; Lamborn, Andrew U.; Mouroulis, Pantazis, Z.; Mouroulis, Pantazis, Z.; Paine, Christopher G.; Soibel, Alexander; Wilson, Daniel W.

    2011-01-01

    The Hyperspectral Thermal Emission Spectrometer (HyTES) is being developed as part of the risk reduction activities associated with the Hyperspectral Infrared Imager (HyspIRI). HyspIRI is one of the Tier 2 Decadal Survey Missions. HyTES will provide information on how to place the filters on the HyspIRI Thermal Infrared Instrument (TIR) as well as provide antecedent science data. The pushbroom design has 512 spatial pixels over a 50-degree field of view and 256 spectral channels between 7.5 micrometers to 12 micrometers. HyTES includes many key enabling state-of-the-art technologies including a high performance convex diffraction grating, a quantum well infrared photodetector (QWIP) focal plane array, and a compact Dyson-inspired optical design. The Dyson optical design allows for a very compact and optically fast system (F/1.6). It also minimizes cooling requirements due to the fact it has a single monolithic prism-like grating design which allows baffling for stray light suppression. The monolithic configuration eases mechanical tolerancing requirements which are a concern since the complete optical assembly is operated at cryogenic temperatures ((is) approximately 100K). The QWIP allows for optimum spatial and spectral uniformity and provides adequate responsivity or D-star to allow 200mK noise equivalent temperature difference (NEDT) operation across the LWIR passband. Assembly of the system is nearly complete. After completion, alignment results will be presented which show low keystone and smile distortion. This is required to minimize spatial-spectral mixing between adjacent spectral channels and spatial positions. Predictions show the system will have adequate signal to noise for laboratory calibration targets.

  16. Elaboration of a chemical decontamination technology: preliminary results

    International Nuclear Information System (INIS)

    background and knowledge evolved at Paks NPP in the course of the chemical decontamination. As a consequence of the long-established achievements, it is practical to develop a procedure based on the methodology of the AP-CITROX (or CORD) technology. It should, however, be noted that the comprehensive analysis of the risk factors, which may be emerged during the application of oxalic acid is unavoidable. In this talk, we will present a brief overview on the fundamental issues of the R and D project focused on the elaboration of the required technology and - based on the results of some recent studies in the fields of solution chemistry, electrochemistry and surface science - summarize the main characteristics of an optimal decontamination procedure. (author)

  17. Quaternary sedimentation and active faulting along the Ecuadorian shelf : preliminary results of the ATACAMES Cruise (2012)

    OpenAIRE

    Michaud, François; Proust, J. N.; Collot, Jean-Yves; Lebrun, J.F.; De Witt, C.; Ratzov, G.; H. Pouderoux; Martillo, C.; Hernandez, M.J.; Loayza, G.; Penafiel, L.; Schenini, Laure; Dano, A.; Gonzalez, M; Barba, D

    2015-01-01

    Selected high-resolution seismic-reflection profiles and multibeam bathymetry acquired along the convergent Ecuador margin during the ATACAMES cruise on onboard the R/V L'Atalante (Jan.15-Feb.18, 2012) allow a preliminary evaluation of the neotectonic development and stratigraphic evolution of the margin based on the sismo-stratigraphic analysis of Quaternary sediment preserved on the margin shelf and upper slope. We present three major preliminary results. (1) The evolution of the Esmeraldas...

  18. EM techniques for archaeological laboratory experiments: preliminary results

    Science.gov (United States)

    Capozzoli, Luigi; De Martino, Gregory; Giampaolo, Valeria; Raffaele, Luongo; Perciante, Felice; Rizzo, Enzo

    2015-04-01

    model. The integration of electric and electromagnetic data allowed us to overcome the limits of each technique, especially in terms of resolution and depth, in humid/saturated conditions was investigated and the effectiveness of three-dimensional acquisitions was studied to better explore archeological sites and reduce the uncertainties related on the interpretation of geophysical analysis. The complexity of the relationship between archaeological features in the subsoil and their geophysical response requires efforts in the interpretation of resulting data. Reference Campana S. and Piro, S., (2009): Seeing the unseen - Geophysics and landscape archaeology., CRC Press, London, 2. No. of pages: 376. ISBN: 978-0-415-44721-8. Conyers, L. and Goodman, D., (1997): Ground-Penetrating Radar: An Introduction for Archaeologists. Walnut Creek, Calif.: AltaMira Press. Davis, J.L. and Annan, A.P. (1989): Ground-penetrating radar for high-resolution mapping of soil and rock stratigraphy. Geophysical Prospecting, 37, 531-551.

  19. Dating of polyhalite and langbeinite: preliminary results from German Zechstein

    Science.gov (United States)

    Neubauer, Franz; Schorn, Anja; Leitner, Christoph; Genser, Johann

    2013-04-01

    formation temperatures are given between 57.1 ° C or more commonly 83 ° C (e.g. Neitzel, 1992 and references therein), is mined as potash ore at the German Zechstein deposits. Neitzel (1992) summarized two main types of langbeinite formation (1) from kainite and halite (due to thermal metamorphism) and (2) from sylvinitic Hartsalz (= mixture of sylvite, kieserite and halite) due to solution metamorphism. The mineral might also form by decomposition of polyhalite to langbeinite and anhydrite during prograde metamorphism. In the following, we discuss the first successful results of polyhalite and langbeinite dating in Zechstein salts of Germany (Morsleben, Neuhof). Extremely fine-grained (grain sizes International Journal of Earth Sciences, DOI 10.1007/s00531-012-0836-6. Neitzel, U., 1992. 100 Jahre Langbeinit. Kali und Steinsalz, 11/1, 7-13. Renne, P. R., Sharp, W. D. Montañez, I. P., Becker, R. A., Zierenberg, R. A., 2001. 40Ar/39Ar dating of Late Permian evaporites, southeastern New Mexico, USA. Earth and Planetary Science Letters, 193, 539-547. Warren, J. K., 2006. Evaporites: Sediments, Resources and Hydrocarbons. Springer, Berlin Heidelberg, 1035 p. Wollmann, G., 2010. Crystallization Fields of Polyhalite and its Heavy Metal Analogues. Ph.D. thesis, University Bergakademie Freiberg. Wollmann, G., Freyer, D., Voigt, W., 2008. Polyhalite and its analogous triple salts. Monatshefte für Chemie, 139, 739-745.

  20. A comparison of results by sequential and concurrent chemo radiotherapy in locally advanced carcinoma esophagus

    Directory of Open Access Journals (Sweden)

    V Bhandari

    2013-01-01

    Full Text Available Aim: Many Trials using sequential and concurrent chemo radiotherapy have been done so far and has established the role of concurrent chemo radiotherapy in treatment of inoperable carcinoma esophagus. In this study, we have compared the results of concurrent chemo radiotherapy with sequential chemo radiotherapy. We have treated inoperable carcinoma esophagus in both the settings and present here the comparison of results in the two settings. Materials and Methods: There were 26 patients of carcinoma esophagus in sequential and 31 in concurrent chemo radiotherapy arm. In sequential arm methotrexate and Cisplatin followed by radiotherapy was given whereas in concurrent arm, Cisplatin was given once weekly along with radiotherapy. Results: The 2 year survival was 38% in sequential and35.5% in the concurrent setting and the median survival was 19.5 and 18 months respectively in the two arms.The toxicities in both the arms were comparable. P value of 0.4774 with confidence interval of 95% was obtained, which is not significant. Dysphagia was improved earlier in sequential than in the concurrent arm. Conclusion: As the results and toxicities in both the arms are almost similar with better symptom control, so larger randomized trials are required to assess the response and the use of methotrexate in sequential chemo radiotherapy can be further explored.

  1. Activation of c-Yes in hepatocellular carcinoma: A preliminary study

    Institute of Scientific and Technical Information of China (English)

    Hah Feng; Hisakazu Iwama; Hisashi Usuki; Hisao Wakabayashi; Kunihiko Izuishi; Hitoshi Yoshiji; Kazutaka Kurokohchi; Shigeki Kuriyama; Tsutomu Masaki; Takako Nonomura; Asahiro Morishita; Gong Jian; Seiji Nakai; Akihiro Deguchi; Naohito Uchida; Takashi Himoto

    2006-01-01

    @@ TO THE EDITOR Hepatocellular carcinoma (HCC) is thought to develop through a multistep process[1]. A long history of viral hepatitis or prolonged exposure to environmental toxins predisposes liver cells to mutations of the genes critical in the control of hepatocyte growth. In fact, both activation of cellular oncogenes and inactivation of tumorsuppressor genes are involved in the development of HCC. Activation of oncogenes by hepatitis virus integration has been shown in the woodchuck animal model[2],although the significance of this finding in human hepatocarcinogenesis is still under investigation.

  2. Long-term results of radiotherapy in primary carcinoma of the vagina

    Energy Technology Data Exchange (ETDEWEB)

    Hegemann, Stefan; Willich, Normann [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Schaefer, Ulrich [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Lippe Hospital, Lemgo (Germany). Dept. of Radiotherapy; Lelle, Ralph [University Hospital, Muenster (Germany). Dept. of Gynecology and Gynecologic Oncology; Micke, Oliver [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Franziskus Hospital, Bielefeld (Germany). Dept. of Radiotherapy and Radiation Oncology

    2009-03-15

    Background: The long-term results of radiotherapy in primary carcinoma of the vagina are not well defined. Patients and Methods: The treatment results of 41 patients with primary malignancies of the vagina were analyzed. The mean follow-up period was 77.3 months (2.3-404 months). The predominant histology was squamous cell carcinoma, FIGO stages I: n = 7 (17.1%), II: n = 13 (31.7%), III: n = 13 (31.7%), and IVa: n = 8 (19.5%). Radiotherapy was the primary treatment for all patients. None of the patients had undergone prior surgery for vaginal carcinoma. The majority of patients received pelvic irradiation, including treatment of the inguinal lymphatics (median dose: 50 Gy). 26 patients received additional intravaginal brachytherapy. Results: Overall, 21 patients (51.2%) achieved complete remission, 17 patients (41.5%) had partial responses, and three patients (7.3%) had no change or progressive disease. The total median survival of the analyzed patients was 41.3 months. The 1-year survival probability was 85.4%, the 5-year survival probability 40.6%, and the 10-year survival probability 27.2%. Univariate analysis revealed a survival advantage for earlier tumor stages (FIGO I and II) compared to advanced stages (FIGO III and IV), with a median survival of 58.1 months compared to 26.8 months. Treatment side effects were tolerable and easily managed. Conclusion: Definite radiotherapy is the treatment of choice for primary carcinomas of the vagina. Considering that primary malignancies of the vagina are typically diseases of the elderly, it should be noted that radiotherapy is especially well tolerated in this population. (orig.)

  3. Spectral CT evaluation of interstitial brachytherapy in pancreatic carcinoma xenografts: preliminary animal experience

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Shudong [Jiangsu University, Department of Radiology, The Affiliated Renmin Hospital, Zhenjiang, Jiangsu (China); Shanghai Jiao tong University, School of Medicine, Department of Radiology, Ruijin Hospital, Shanghai (China); Huang, Wei; Song, Qi; Lin, Xiaozhu; Wang, Zhongmin; Chen, Kemin [Shanghai Jiao tong University, School of Medicine, Department of Radiology, Ruijin Hospital, Shanghai (China); Chen, Yerong [Jiangsu University, Department of Radiology, The Affiliated Renmin Hospital, Zhenjiang, Jiangsu (China)

    2014-09-15

    We sought to evaluate the capability of spectral CT to detect the therapeutic response to {sup 125}I interstitial brachytherapy in a pancreatic carcinoma xenograft nude mouse model. Twenty mice bearing SWl990 human pancreatic cancer cell xenografts were randomly separated into two groups: experimental (n = 10; 1.0 mCi) and control (n = 10; 0 mCi). After a two-week treatment, spectral CT was performed. Contrast-to-noise ratio (CNR) and iodine concentration (IC) in the lesions were measured and normalized to the muscle tissue, and nIC CD31 immunohistochemistry was used to measure microvessel density (MVD). The relationships between the nIC and MVD of the tumours were analysed. The nIC of the experimental group was significantly lower than that of the control group during the multiphase examination. A significant difference in the MVD was observed between the two groups (P <0.001). The nIC values of the three-phase scans have a certain positive correlation with MVD (r = 0.57, p < 0.0001; r = 0.48, p = 0.002; r = 0.63, p = 0.0017 in the 10, 25, and 60 s phase, respectively). Spectral CT can be a useful non-invasive imaging modality in evaluating the therapeutic effect of {sup 125}I interstitial brachytherapy to a pancreatic carcinoma. (orig.)

  4. Results of radiotherapy and a combined radio- and chemotherapy for hypopharyngeal carcinomas

    International Nuclear Information System (INIS)

    We analyzed the results of radiotherapy in 36 patients with hypopharyngeal carcinoma. The overall 2-year and 5-year survival rates were 45.3% and 31.1%, respectively. For 23 patients given radical irradiation, the corresponding figures were 37.8% and 28.3%. However, in 16 patients receiving a combined therapy of radical irradiation and chemotherapy, mainly an intraarterial injection of cisplatin, the survivals were better; the 2-year survival rate was 50.0% and four patients have survived for more than three years without recurrence. In managing patients with hypopharyngeal carcinoma, this combined therapy would improve therapeutic outcome and also assist in larynx preservation. (J.P.N.)

  5. Decision-Making in Flight with Different Convective Weather Information Sources: Preliminary Results

    Science.gov (United States)

    Latorella, Kara A.; Chamberlain, James P.

    2004-01-01

    This paper reports preliminary and partial results of a flight experiment to address how General Aviation (GA) pilots use weather cues to make flight decisions. This research presents pilots with weather cue conditions typically available to GA pilots in visual meteorological conditions (VMC) and instrument meteorological conditions (IMC) today, as well as in IMC with a Graphical Weather Information System (GWIS). These preliminary data indicate that both VMC and GWIS-augmented IMC conditions result in better confidence, information sufficiency and perceived performance than the current IMC condition. For all these measures, the VMC and GWIS-augmented conditions seemed to provide similar pilot support. These preliminary results are interpreted for their implications on GWIS display design, training, and operational use guidelines. Final experimental results will compare these subjective data with objective data of situation awareness and decision quality.

  6. Preliminary results from the 51Cr neutrino source experiment in GALLEX

    International Nuclear Information System (INIS)

    The GALLEX collaboration performed a second 51Cr neutrino source experiment during fall 1995. The full results from this second source experiment will not be available before the end of 1996. Meanwhile, we present a short description and preliminary results in this informal note. The (preliminary) value of the activity obtained form direct measurements has been found equal to (68.7 ±0.7) PBq (with 1-sigma error). This value, which is about 10% higher than the activity of the first source, was achieved by optimizing the irradiation conditions in the Siloacute e reactor and doing a longer irradiation of the enriched chromium. Preliminary results show that the ratio, R, of the radiochemically determined activity from 71Ge counting (57.1 ± PBq) to the directly measured activity is (0.83 ± 0.10). The combined value of R for the two source experiments is (0.92 ± 0.08)

  7. Long-term results of curative intraluminal high dose rate brachytherapy for endobronchial carcinoma

    International Nuclear Information System (INIS)

    The treatment strategy of central lung tumors is not established. Intraluminal brachytherapy (ILBT) is widely used for palliative treatment of endobronchial tumors, however, it is also a promising option for curative treatment with limited data. This study evaluates the results after ILBT for endobronchial carcinoma. Sixteen-endobronchial carcinoma of 13 patients treated with ILBT in curative intent for 2000 to 2008 were retrospectively reviewed. ILBT using high dose rate 192 iridium thin wire system was performed with 5 Gy/fraction at mucosal surface. The patient age ranged from 57 to 82 years old with median 75 years old. The 16 lesions consisted of 13 central endobronchial cancers including 7 roentgenographically occult lung cancers and 3 of tracheal cancers. Of them, 10 lesions were treated with ILBT of median 20 Gy combined with external beam radiation therapy of median 45 Gy and 6 lesions were treated with ILBT alone of median 25 Gy. Median follow-up time was 32.5 months. Two-year survival rate and local control rate were 92.3% and 86.2%, respectively. Local recurrences were observed in 2 lesions. Three patients died due to lung cancer (1 patient) and intercurrent disease (2 patients). Complications greater than grade 2 were not observed except for one grade 3 dyspnea. ILBT combined with or without EBRT might be a curative treatment option in inoperable endobronchial carcinoma patients with tolerable complication

  8. Sequential hemibody and local irradiation with combination chemotherapy for small cell lung carcinoma: a preliminary analysis

    International Nuclear Information System (INIS)

    Sequential hemibody irradiation (SHB) was integrated with combination chemotherapy and local irradiation (LRT) in the induction and consolidation phases of a therapeutic protocol for small cell lung carcinoma (SCLC). Forty-one previously untreated patients were entered into this program. Among 38 evaluable patients (20 with limited disease [LD] and 18 with extensive disease [ED]), the overall response rate was 63% (90% in LD and 33% in ED patients). The estimated overall survival is 8.1 months. The major toxicity has been myelosuppression - especially thrombocytopenia. The frequency of previously described acute radiation syndromes and radiation pneumonitis associated with hemibody irradiation have been substantially decreased at the current dosage with premedication and shielding techniques

  9. 76 FR 2655 - Honey From Argentina: Preliminary Results of Antidumping Duty Administrative Review

    Science.gov (United States)

    2011-01-14

    ...: Honey From Argentina, 66 FR 63672 (December 10, 2001). On December 1, 2009, the Department published in... Memorandum; see e.g., Honey from Argentina: Final Results of Antidumping Duty Administrative Review, 70 FR... to Patagonik. See, e.g., Honey From Argentina: Preliminary Results of New Shipper Review, 71 FR...

  10. Registration and matching of tomographic and projection images: preliminary results of an hybrid solution in radiosurgery

    International Nuclear Information System (INIS)

    A new method for 2-dimensional/3-dimensional registration, applied to Magnetic Resonance Imaging (3-dimensional) and to X-Ray angiography (2-dimensional), has been adapted and used for planning treatment in radiosurgery. The imaging flow needed for planning radiosurgery is considerable and using registration technique would make lighter the imaging protocol without restricting planning. We describe the preliminary results of the evaluation giving criteria to compare registration technique and localization using stereotactic frame, which is the gold standard method. Preliminary results obtained during this first step in validating registration put forward which kind of MRI sequence are more suitable to registration. (authors)

  11. Early results of combined chemotherapy followed by Co60 radiotherapy in patients with undifferentiated pulmonary carcinoma

    International Nuclear Information System (INIS)

    The results of combined treatment of a group of 17 patients with the diagnosis of microcellular pulmonary carcinoma are reported. The received chemotherapy with three drugs (cyclophosphamide, vincristine, methotrexate) and radiotherapy from Co60 by the sandwich method as suggested by the ALGB group. The obtained results resembled those reported from other clinical centres: 29% of the patients survived one year after treatment onset. Complete remission was achieved in 60% of cases, its mean duration was 11.3 months, and the mean survival time of these patients was 15.5 months. Side effects were slight, and the survival time of the patients achieving complete remission was evidently prolonged. (author)

  12. Cognitive Task Analysis of Business Jet Pilots' Weather Flying Behaviors: Preliminary Results

    Science.gov (United States)

    Latorella, Kara; Pliske, Rebecca; Hutton, Robert; Chrenka, Jason

    2001-01-01

    This report presents preliminary findings from a cognitive task analysis (CTA) of business aviation piloting. Results describe challenging weather-related aviation decisions and the information and cues used to support these decisions. Further, these results demonstrate the role of expertise in business aviation decision-making in weather flying, and how weather information is acquired and assessed for reliability. The challenging weather scenarios and novice errors identified in the results provide the basis for experimental scenarios and dependent measures to be used in future flight simulation evaluations of candidate aviation weather information systems. Finally, we analyzed these preliminary results to recommend design and training interventions to improve business aviation decision-making with weather information. The primary objective of this report is to present these preliminary findings and to document the extended CTA methodology used to elicit and represent expert business aviator decision-making with weather information. These preliminary findings will be augmented with results from additional subjects using this methodology. A summary of the complete results, absent the detailed treatment of methodology provided in this report, will be documented in a separate publication.

  13. Nb/NiCu bilayers in single and stacked superconductive tunnel junctions: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Pepe, G.P. E-mail: ruotolo_antonio@tin.it; Ruotolo, A.; Parlato, L.; Peluso, G.; Ausanio, G.; Carapella, G.; Latempa, R

    2004-05-01

    We present preliminary experimental results concerning both single and stacked tunnel junctions in which one of the electrodes was formed by a superconductor/ferromagnet (S/F) bi-layer. In particular, in the stacked configuration a Nb/NiCu bi-layer was used as the intermediate electrode, and it was probed by tunneling on both sides. Tunnel junctions have been characterized in terms of current-voltage characteristics (IVC), and differential conductance. Preliminary steady-state injection-detection measurements performed in the stacked devices at T=4.2 K are also presented and discussed.

  14. Nb/NiCu bilayers in single and stacked superconductive tunnel junctions: preliminary results

    International Nuclear Information System (INIS)

    We present preliminary experimental results concerning both single and stacked tunnel junctions in which one of the electrodes was formed by a superconductor/ferromagnet (S/F) bi-layer. In particular, in the stacked configuration a Nb/NiCu bi-layer was used as the intermediate electrode, and it was probed by tunneling on both sides. Tunnel junctions have been characterized in terms of current-voltage characteristics (IVC), and differential conductance. Preliminary steady-state injection-detection measurements performed in the stacked devices at T=4.2 K are also presented and discussed

  15. Preliminary results of the scientific experiments on the Kosmos-936 biosatellite

    Science.gov (United States)

    1977-01-01

    The scientific equipment and experiments on the Kosmos-936 biosatellite are described, including various ground controls and the lab unit for studies at the descent vehicle landing site. Preliminary results are presented of the physiological experiment with rats, biological experiments with drosophila and higher and lower plants, and radiation physics and radiobiology studies for the planning of biological protection on future space flights. The most significant conclusion from the preliminary data is that rats tolerate space flight better with an artificial force of gravity.

  16. Proteomic Study of HPV-Positive Head and Neck Cancers: Preliminary Results

    Directory of Open Access Journals (Sweden)

    Géraldine Descamps

    2014-01-01

    Full Text Available Human papillomavirus (HPV was recently recognized as a new risk factor for head and neck squamous cell carcinoma. For oropharyngeal cancers, an HPV+ status is associated with better prognosis in a subgroup of nonsmokers and nondrinkers. However, HPV infection is also involved in the biology of head and neck carcinoma (HNC in patients with a history of tobacco use and/or alcohol consumption. Thus, the involvement of HPV infection in HN carcinogenesis remains unclear, and further studies are needed to identify and analyze HPV-specific pathways that are involved in this process. Using a quantitative proteomics-based approach, we compared the protein expression profiles of two HPV+ HNC cell lines and one HPV− HNC cell line. We identified 155 proteins that are differentially expressed (P<0.01 in these three lines. Among the identified proteins, prostate stem cell antigen (PSCA was upregulated and eukaryotic elongation factor 1 alpha (EEF1α was downregulated in the HPV+ cell lines. Immunofluorescence and western blotting analyses confirmed these results. Moreover, PSCA and EEF1α were differentially expressed in two clinical series of 50 HPV+ and 50 HPV− oral cavity carcinomas. Thus, our study reveals for the first time that PSCA and EEF1α are associated with the HPV-status, suggesting that these proteins could be involved in HPV-associated carcinogenesis.

  17. Retrospective study of the local control and the cosmetic result of 147 face carcinomas after interstitial brachytherapy

    International Nuclear Information System (INIS)

    The purpose was to evaluate retrospectively the local control rate and the cosmetic results for patients that received an interstitial brachytherapy for a base or spino-cellular carcinoma of face orifices areas. The interstitial brachytherapy by iridium 192 is an excellent alternative to surgery in the skin carcinomas of the face, as well at the level of local control as the cosmetic and functional results. (N.C.)

  18. 77 FR 73422 - Seamless Refined Copper Pipe and Tube From Mexico: Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2012-12-10

    ... International Trade Administration Seamless Refined Copper Pipe and Tube From Mexico: Preliminary Results of... administrative review of the antidumping duty order on seamless refined copper pipe and tube from Mexico. The... description, available in Seamless Refined Copper Pipe and Tube From Mexico and the People's Republic of...

  19. Three-dimensional Simulations of Thermonuclear Detonation with α-Network: Numerical Method and Preliminary Results

    Science.gov (United States)

    Khokhlov, A.; Domínguez, I.; Bacon, C.; Clifford, B.; Baron, E.; Hoeflich, P.; Krisciunas, K.; Suntzeff, N.; Wang, L.

    2012-07-01

    We describe a new astrophysical version of a cell-based adaptive mesh refinement code ALLA for reactive flow fluid dynamic simulations, including a new implementation of α-network nuclear kinetics, and present preliminary results of first three-dimensional simulations of incomplete carbon-oxygen detonation in Type Ia Supernovae.

  20. 78 FR 34644 - Stainless Steel Plate in Coils From Belgium: Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2013-06-10

    ... International Trade Administration Stainless Steel Plate in Coils From Belgium: Preliminary Results of... administrative review of the antidumping duty order on stainless steel plate in coils (steel plate) from Belgium...: Scope of the Order The product covered by this order is certain stainless steel plate in...

  1. 75 FR 81217 - Stainless Steel Plate in Coils From Belgium: Preliminary Results of Full Sunset Review

    Science.gov (United States)

    2010-12-27

    ... International Trade Administration Stainless Steel Plate in Coils From Belgium: Preliminary Results of Full... review of the countervailing duty (``CVD'') order on certain stainless steel plate in coils from Belgium... June 2, 2010, the Department initiated the second sunset review of the CVD order on stainless...

  2. 78 FR 7395 - Stainless Steel Bar From India: Preliminary Results of Antidumping Duty Administrative Review...

    Science.gov (United States)

    2013-02-01

    ... Determination of Sales at Less Than Fair Value: Stainless Steel Bar from India, 59 FR 66915, 66921 (December 28... International Trade Administration Stainless Steel Bar From India: Preliminary Results of Antidumping Duty... the antidumping duty order on stainless steel bar (SSB) from India. The period of review (POR)...

  3. The effect of parental involvement in CBT of anxious children: Preliminary results from a RCT study

    DEFF Research Database (Denmark)

    Esbjørn, Barbara Hoff; Breinholst, Sonja; Reinholdt-Dunne, Marie Louise;

    2011-01-01

    Esbjørn, B. H., Breinholst, S., Reinholdt-Dunne, M. L., & Leth, I. (2011). The effect of parental involvement in CBT of anxious children: Preliminary results from a RCT study. Poster accepted for the Association for Behavioral and Cognitive Therapies, Toronto, Canada....

  4. 76 FR 26241 - Polyethylene Retail Carrier Bags From Thailand: Extension of Time Limit for Preliminary Results...

    Science.gov (United States)

    2011-05-06

    ..., 75 FR 60076 (September 29, 2010). The preliminary results of this administrative review are currently... International Trade Administration Polyethylene Retail Carrier Bags From Thailand: Extension of Time Limit for... polyethylene retail carrier bags from Thailand for the period August 1, 2009, through July 31, 2010....

  5. Preliminary Results from Second Phase Sea Testing of the Wave Dragon Prototype Wave Energy Converter

    DEFF Research Database (Denmark)

    Soerensen, Hans Chr.; Tedd, James; Friis-Madsen, Erik; Kofoed, Jens Peter

    2006-01-01

    In March 2006 the prototype Wave Dragon has been redeployed to a more energetic site in Nissum Bredning an inland sea in Western Denmark. This has followed a period of renovation of many aspects of the device which have resulted in 20% higher energy output. This paper describes the preliminary...

  6. 77 FR 42273 - Solid Urea From the Russian Federation: Preliminary Results of Antidumping Duty Administrative...

    Science.gov (United States)

    2012-07-18

    ... Revocation in Part, 76 FR 53404 (August 26, 2011). \\3\\ See Solid Urea From the Russian Federation: Extension of Time Limit for Preliminary Results of Antidumping Duty Administrative Review, 77 FR 17410 (March...: Final Modification, 77 FR 8101 (February 14, 2012) (``Final Modification for Reviews''). When...

  7. 78 FR 28192 - Polyethylene Retail Carrier Bags From Thailand: Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2013-05-14

    ... Carrier Bags From Thailand, 75 FR 48940 (August 12, 2010) (Section 129 Determination). Preliminary Results....69 Sun Pack Inter Co. Ltd 4.69 Apple Film Company, Ltd 4.69 Trinity Pac Co. Ltd 122.88 * No shipments... Antidumping and Countervailing Duty Proceedings: Assessment of Antidumping Duties, 68 FR 23954 (May 6,...

  8. Gas enhanced magnetic resonance angiography of the cerebrum using carbon dioxide and oxygen - preliminary results

    DEFF Research Database (Denmark)

    Pedersen, Mads Møller; Hansen, Kristoffer Lindskov; Ohlhues, Anders;

    meninges may obscure the signal from the arteries of interest. It is known that oxygen enhances the T1-weighted signal and that carbon dioxide increases the arterial blood flow. This paper presents preliminary results of gas enhanced MRA using combinations of atmospheric air, O2 and CO2. Subjects and...

  9. Preliminary results of the round-robin testing of F82H

    Energy Technology Data Exchange (ETDEWEB)

    Shiba, K.; Yamanouchi, N.; Tohyama, A.

    1996-10-01

    Preliminary results of metallurgical, physical and mechanical properties of low activation ferritic steel F82H (IEA heat) were obtained in the round-robin test in Japan. The properties of IEA heat F82H were almost the same as the original F82H.

  10. 77 FR 61742 - Certain Lined Paper Products From India: Preliminary Results of Countervailing Duty...

    Science.gov (United States)

    2012-10-11

    ... Duty Orders: Certain Lined Paper Products from India and Indonesia, 71 FR 56949 (September 28, 2006... International Trade Administration Certain Lined Paper Products From India: Preliminary Results of... administrative review of the countervailing duty order on certain lined paper products from India. The period...

  11. 78 FR 62584 - Certain Lined Paper Products From India: Preliminary Results of Countervailing Duty...

    Science.gov (United States)

    2013-10-22

    ... Duty Orders: Certain Lined Paper Products from India and Indonesia, 71 FR 56949 (September 28, 2006... International Trade Administration Certain Lined Paper Products From India: Preliminary Results of... administrative review of the countervailing duty (CVD) order on certain lined paper products from India....

  12. 76 FR 47558 - Polyethylene Terephthalate Film, Sheet, and Strip From India: Preliminary Results of...

    Science.gov (United States)

    2011-08-05

    ... interest-free contingent liability loans See, e.g., PET Film Preliminary Results of 2003 Review, 70 FR at... Terephthalate Film, Sheet, and Strip (PET Film) from India, 67 FR 44179 (July 1, 2002). On July 1, 2010, the... Administrative Review, 75 FR 38074 (July 1, 2010). The Department received a request for review from...

  13. 77 FR 32503 - Certain Polyester Staple Fiber From Taiwan: Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2012-06-01

    ... Review, 75 FR 39208 (July 8, 2010). \\2\\ See Initiation of Antidumping and Countervailing Duty Administrative Reviews and Requests for Revocation in Part, 76 FR 37781 (June 28, 2011). On January 30, 2012, in...: Extension of Time Limit for Preliminary Results of Antidumping Duty Administrative Review, 77 FR...

  14. Breast-conserving surgery after neoadjuvant chemotherapy in patients with locally advanced cancer. Preliminary results

    OpenAIRE

    VERGINE, M.; SCIPIONI, P.; GARRITANO, S.; COLANGELO, M.; Di Paolo, A; LIVADOTI, G.; MATURO, A.; Monti, M

    2013-01-01

    Neoadjuvant chemotherapy (NACT) in locally advanced breast tumors may allow an adequate control of the disease impossible with surgery alone. Moreover, NACT increases the chance of breast-conserving surgery. Between 2008 and 2012, we treated with NACT 83 patients with locally advanced breast cancer. We report the preliminary results evaluating the impact of NACT on the type of surgery.

  15. Preliminary results from a laboratory study of charging mechanisms in a dusty plasma

    International Nuclear Information System (INIS)

    A laboratory investigation has been developed to experimentally study the interaction of micron sized particles with plasmas and electromagnetic radiation. The intent is to investigate under what conditions particles of various compositions and sizes become charged, or discharged, while exposed to an electron beam. Primary emphasis in this report is on secondary emission of electrons. Preliminary results are presented

  16. 77 FR 73615 - Lightweight Thermal Paper From Germany; Preliminary Results of Antidumping Duty Administrative...

    Science.gov (United States)

    2012-12-11

    ... Thermal Paper from Germany and the People's Republic of China, 73 FR 70959 (November 24, 2008) (Orders...: Assessment of Antidumping Duties, 68 FR 23954 (May 6, 2003). Assessment of Antidumping Duties We intend to... International Trade Administration Lightweight Thermal Paper From Germany; Preliminary Results of...

  17. 78 FR 15686 - Certain Frozen Warmwater Shrimp From Thailand: Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2013-03-12

    ... FR 40881, 40883 (July 12, 2011); see also the ``Preliminary Determination To Revoke Order, In Part... Administrative Review, 73 FR 12088 (March 6, 2008), unchanged in Certain Frozen Warmwater Shrimp From Thailand: Final Results and Final Partial Rescission of Antidumping Duty Administrative Review, 73 FR...

  18. 76 FR 4292 - Certain Frozen Fish Fillets From the Socialist Republic of Vietnam: Preliminary Results of...

    Science.gov (United States)

    2011-01-25

    ... Fillets from the Socialist Republic of Vietnam, 68 FR 47909 (August 12, 2003) (``Order''). The Department... Socialist Republic of Vietnam (``Verification Report''), issued concurrently with these preliminary results... Antidumping Duty New Shipper Reviews, 75 FR 57261(September 20, 2010). Surrogate Country and Surrogate...

  19. Investigation of the results of therapy of anaplastic thyroid gland carcinomas

    International Nuclear Information System (INIS)

    The results of the treatment of 28 patients with an anaplastic thyroid gland carcinoma are investigated, to see whether an optimal therapy is indicated. The execution of an operation before radiotherapy does not appear to improve the prognosis (statistically this conclusion is not wholly justified). The presence of metastases at the beginning of the therapy gave rise to a worse prognosis than the absence of metastases. The combination treatment of chemotherapy and either surgery or radiotherapy was only applied to two patients so no conclusions can be made about its benefit. (C.F.)

  20. Long-term results of curative intraluminal high dose rate brachytherapy for endobronchial carcinoma

    Directory of Open Access Journals (Sweden)

    Kawamura Hidemasa

    2012-07-01

    Full Text Available Abstract Background The treatment strategy of central lung tumors is not established. Intraluminal brachytherapy (ILBT is widely used for palliative treatment of endobronchial tumors, however, it is also a promising option for curative treatment with limited data. This study evaluates the results after ILBT for endobronchial carcinoma. Method Sixteen-endobronchial carcinoma of 13 patients treated with ILBT in curative intent for 2000 to 2008 were retrospectively reviewed. ILBT using high dose rate 192 iridium thin wire system was performed with 5 Gy/fraction at mucosal surface. The patient age ranged from 57 to 82 years old with median 75 years old. The 16 lesions consisted of 13 central endobronchial cancers including 7 roentgenographically occult lung cancers and 3 of tracheal cancers. Of them, 10 lesions were treated with ILBT of median 20 Gy combined with external beam radiation therapy of median 45 Gy and 6 lesions were treated with ILBT alone of median 25 Gy. Results Median follow-up time was 32.5 months. Two-year survival rate and local control rate were 92.3% and 86.2%, respectively. Local recurrences were observed in 2 lesions. Three patients died due to lung cancer (1 patient and intercurrent disease (2 patients. Complications greater than grade 2 were not observed except for one grade 3 dyspnea. Conclusions ILBT combined with or without EBRT might be a curative treatment option in inoperable endobronchial carcinoma patients with tolerable complication.

  1. Preliminary Study of MR Diffusion Tensor Imaging of the Liver for the Diagnosis of Hepatocellular Carcinoma.

    Directory of Open Access Journals (Sweden)

    Xinghui Li

    Full Text Available To evaluate the feasibility of differentiating between hepatocellular carcinomas (HCC and healthy liver using diffusion tensor imaging (DTI.All subjects underwent an abdominal examination on a 3.0T MRI scanner. Two radiologists independently scored the image quality (IQ. An optimal set of DTI parameters was obtained from a group of fifteen volunteers with multiple b-values (100, 300, 500, and 800 s/mm2 and various diffusion-encoding directions (NED = 6, 9, and 12using two way ANOVA analysis. Eighteen Patients with HCC underwent DTI scans with the optimized parameters. Fractional anisotropy(FA and average apparent diffusion coefficient (ADC values were measured. The differences of FA and ADC values between liver healthy region and HCC lesion were compared through paired t tests.There were no significant changes in liver IQ and FA/ADC values with increased NED(P >0.05, whereas the liver IQ and FA/ADC values decreased significantly with increased b-values(P <0.05. Good IQ, acceptable scan time and reasonable FA/ADC values were acquired using NED = 9 with b-value of (0,300 s/mm2. Using the optimized DTI sequence, ADC value of the tumor lesion was significantly lower than that of the healthy liver region (1.30 ± 0.34×10-3 vs 1.52 ± 0.27×10-3 mm2/s, P = 0.013, whereas the mean FA value of the tumor lesion (0.42 ± 0.11 was significantly higher than the normal liver region (0.32 ± 0.10 (P = 0.004.Either FA or ADC value from DTI can be used to differentiate HCC from healthy liver. HCC lead to higher FA value and lower ADC value on DTI than healthy liver.

  2. Analysis of treatment and results in patients with advanced hypopharyngeal carcinomas

    International Nuclear Information System (INIS)

    Between 1991 and 1997, 42 patients with advanced stage III or IVA or IVB hypopharyngeal cancer received primary treatment at our clinic. Treatment and results in these cases were analyzed retrospectively. Thirty three patients with resectable hypopharyngeal carcinomas received 1-3 courses of neoadjuvant chemotherapy (NAC) involving a combination of cisplatin 60 mg/m2 and 5-fluorouracil 800 or 1,000 mg/m2 x 5 days, followed by total laryngopharyngectomy plus postoperative radiotherapy in 24 patients (group A) or followed by 70 Gy radiotherapy with radiation sensitizer in 9 patients because of self rejection of the operation (group B). Nine patients with unresectable hypopharyngeal carcinomas received neoadjuvant chemotherapy followed by radiotherapy or received radiotherapy only (group C). For the entire group, 5-year overall survival was 38% (group A 53%, group B 22%, group C 0%). The survival was statistically better (p<0.05) in group A than in group B. Better results were obtained for combined therapy including radical surgery in terms of overall survival. The response rate of NAC was 70%. In the patients who received operation, clinical and pathological CR rate was (8% in primary lesion, clinical CR rate was 5% and pathological CR rate was 23% in regional lymph nodes. Therefore sensitivity of the clinical CR evaluation was 50% in primary lesion and 20% in regional lymph nodes. Specificity of the clinical CR evaluation was 95% in primary lesion and 100% in regional lymph nodes. (author)

  3. Treatment of locally recurrent rectal carcinoma--results and prognostic factors

    International Nuclear Information System (INIS)

    Purpose: To assess the local control and survival in patients who received pelvic irradiation for locally recurrent rectal carcinoma. Methods and Materials: The records of 519 patients with locally recurrent rectal carcinoma treated principally with external-beam radiation therapy between 1975 to 1985 at a single institute were retrospectively reviewed. These included 326 patients who relapsed locally following previous abdominoperineal resection, 151 after previous low anterior resection, and 42 after previous local excision or electrocoagulation for the primary. No patients had received adjuvant radiation therapy or chemotherapy for the primary disease. Concurrent extrapelvic distant metastases were found in 164 (32%) patients at local recurrence and, in the remaining 355, the relapse was confined to the pelvis. There were 290 men and 229 women whose age ranged from 23 to 91 years (median = 65). Median time from initial surgery to radiation therapy for local recurrence was 18 months (3-138 months). Radiation therapy was given with varying dose-fractionation schedules, total doses ranging from 4.4 to 65.0 Gy (median = 30 Gy) over 1 to 92 days (median = 22 days). For 214 patients who received a total dose ≥35 Gy, radiation therapy was given in 1.8 to 2.5 Gy daily fractions. Results: The median survival was 14 months and the median time to local disease progression was 5 months from date of pelvic irradiation. The 5-year survival was 5%, and the pelvic disease progression-free rate was 7%. Twelve patients remained alive and free of disease at 5 years after pelvic irradiation. Upon multivariate analysis, overall survival was positively correlated with ECOG performance status (p = 0.0001), absence of extrapelvic metastases (p = 0.0001), long intervals from initial surgery to radiation therapy for local recurrence (p 0.0001), total radiation dose (p = 0.0001), and absence of obstructive uropathy (p = 0.0013). Pelvic disease progression-free rates were positively

  4. P53 overexpression in head and neck carcinoma and radiotherapy results

    International Nuclear Information System (INIS)

    Purpose: P53 gene mutations are the common genetic changes encountered in human cancers, and there is extensive evidence that the P53 status may determine tumor response to therapy. This study was carried out to investigate whether there is any correlation between accumulation (overexpression) of P53 protein and poor prognosis in patients with head and neck carcinomas treated with radical radiotherapy. Methods and Materials: Seventy-nine patients with head and neck carcinomas who were diagnosed and treated in 1989-90 with curative radiotherapy were studied retrospectively. Paraffin sections from archival material were studied using immunohistochemical staining (IHC) with mouse monoclonal antibodies (D0-7) to human P53 protein. Univariate and multivariate analysis of loco-regional tumor control and patient survival were performed on possible prognostic factors. Results: Forty-two (53%) patients showed positive IHC staining in their tumors. Fifty-three percent of the laryngeal, 64% of the oropharyngeal, and 43% of the oral cavity carcinomas showed P53 overexpression. All tumor specimens with vascular, lymphatic, and/or sarcolemmal invasion showed P53 overexpression. The proportion of tumor-stained nuclei was higher in the poorly differentiated than in the well and moderately differentiated tumors (p < 0.05), but there was no correlation with the patient overall or disease-free 5-year actuarial survival. There was no difference in the 5-year actuarial survival and disease-free survival between patients with P53 immunostaining in their tumors and those with no immunostaining (59% vs. 65% and 57% vs. 51%, respectively). The TNM tumor stage was the most significant prognostic factor with 5-year actuarial survival of 87% for early and 14% for late stages (p << 0.0001). There was a significant correlation between immunostaining and history of smoking (p = 0.02). Conclusion: The data demonstrate that the P53 accumulation as detected by immunohistochemical staining in a

  5. Vapour explosions (fuel-coolant interactions) resulting from the sub-surface injection of water into molten metals: preliminary results

    International Nuclear Information System (INIS)

    Preliminary experiments are reported on the relationship between the injection mode of contact and the occurrence and magnitude of vapour explosions. Water was injected beneath the surface of molten metals, chiefly tin at 250 to 9000C. Vapour explosions occurred in many, but not all, cases. The results are compared with Dullforce's observations (Culham Report (CLM-P424) on the dropping mode of contact and it appears that rather different behaviour is found; in particular, the present results suggest that the Temperature Interaction Zone is different for the two modes of contact. (author)

  6. Preliminary results of natural radioactivity measurements in the southern part of Ethiopia

    International Nuclear Information System (INIS)

    The paper presents the first results of natural radioactivity measurements in the Southern part of Ethiopia (Bale Zone-Oromiya Regional State). The preliminary results indicate that radiation levels in the mining areas of Kallido Mountain are elevated compared with those in the town of Negele Borena (background area). Both external gamma radiation and alpha surface contamination levels are significantly elevated above local background levels

  7. Intracoronary irradiation with rhenium 188 to reduce restenosis following a coronary angioplasty. Preliminary results

    International Nuclear Information System (INIS)

    This paper shows the preliminary results from our contribution to a coordinated project with the International Atomic Energy Agency, which corroborates that the intracoronary irradiation allows to reduce the restenosis following a percutaneous transluminal coronary angioplasty (PTCA) in patients with ischemic cardiopathy as a result of neointima hyperplasia reduction. In the treatment, both beta and gamma emitters can be used, but with the latter (specifically with rhenium 188), its is possible to use an angioplasty balloon catheter for therapy purposes

  8. Results of radiotherapy for cancer of head and neck region, 3. Pharyngeal cancer, carcinoma of the oral tongue and oral cavity

    Energy Technology Data Exchange (ETDEWEB)

    Fujimura, Noriharu; Shinzato, Jintetsu; Watanabe, Keikichi; Habu, Kenjiro; Hirayama, Haruyuki

    1988-04-01

    A total of 122 patients with pharyngeal cancer (55 cases), carcinoma of the oral tongue (28 cases) and carcinoma of the oral cavity (39 cases) were treated by external irradiation at the Department of Radiology, Kumamoto National Hospital. In the retrospective study, therapeutic results in pharyngeal cancer (39 cases), in carcinoma of the oral tongue (20 cases) and in carcinoma of the oral cavity (30 cases) were analyzed. 1) Thirty-nine cases of pharyngeal cancer consitituted 9 cases of epipharyngeal cancer, 17 of mesopharyngeal cancer and 13 of hypopharyngeal cancer. The five-year survival rate was 35 % for epipharyngeal cancer, 13 % for mesopharyngeal cancer and 10 % for hypopharyngeal cancer. 2) Twenty cases of carcinoma of the oral tongue were treated by external irradiation and intraoral electron therapy. The five-year survival rate was 28 %. Three cases survived more than five years ; 2 were preoperative irradiation and 1 undergoing a curative irradiation was salvaged with surgery. 3) Thirty cases of carcinoma of the oral cavity consitituted 10 cases of carcinoma of the floor of the mouth, 9 of carcinoma of the cheek mucosa, 7 of carcinoma of the gum, 2 of carcinoma of the hard palate and 2 of carcinoma of the lip. An overall survival rate was 27 %. Five cases survived more than five years ; 3 were carcinoma of the gum and 2 were carcinoma of the cheek mucosa.

  9. Invasive neuroendocrine carcinoma of the breast: a population-based study from the surveillance, epidemiology and end results (SEER) database

    International Nuclear Information System (INIS)

    Neuroendocrine carcinoma (NEC) of the breast is a rare type of carcinoma that has not been well studied or characterized. Of the limited number of studies reported in the literature, most are case reports. A few small retrospective series studies have been reported. We reviewed data on 142 cases of mammary NEC recorded in the surveillance, epidemiology, and end results (SEER) database during 2003–2009 and evaluated disease incidence and patient age, sex, and race/ethnicity; clinicopathologic characteristics; and survival in comparison to invasive mammary carcinoma, not otherwise specified. We also performed univariate and multivariate analyses to identify prognostic factors in this disease. Review of the 142 SEER cases revealed that NEC is an aggressive variant of invasive mammary carcinoma. It generally occurred in older women (>60 years); present with larger tumor size (>20 mm), higher histologic grade, and higher clinical stage; and result in shorter overall survival and disease-specific survival than invasive mammary carcinoma, not otherwise specified (IMC-NOS). Overall survival and disease-specific survival were shorter in NEC at each stage than in IMC-NOS of the same stage. Furthermore, when all NEC and IMC-NOS cases were pooled together, neuroendocrine differentiation itself was an adverse prognostic factor independent of other known prognostic factors, including age, tumor size, nodal status, histologic grade, estrogen/progesterone receptor status, and therapy. NEC is a rare but aggressive type of mammary carcinoma. Novel therapeutic approaches should be explored for this uniquely clinical entity

  10. Treatment results for nasopharyngeal carcinoma in the modern era: The Hong Kong experience

    International Nuclear Information System (INIS)

    Purpose: To analyze the treatment results achievable for nasopharyngeal carcinoma in the modern era to identify the key failures for future improvement and to provide an updated baseline for future trials. Methods and materials: The results of 2687 consecutive patients treated at all public oncology centers in Hong Kong during 1996-2000 were retrospectively analyzed. The stage distribution (by American Joint Committee on Cancer and International Union Against Cancer staging system, 1997) was 7% Stage I, 41% Stage II, 25% Stage III, and 28% Stage IVA-B. All patients were irradiated with 6-MV photons and the median total dose was 66 Gy. Only 23% of patients had additional treatment with chemotherapy. Results: The 5-year local, nodal, and distant failure-free rates were 85%, 94%, and 81%, respectively; patients with local failure had significantly higher risk of nodal and distant failures. The 5-year progression-free, overall, and cancer-specific survival rates were 63%, 75%, and 80%, respectively. The presenting stage was the most important prognostic factor for all endpoints: with overall survival decreasing from 90% for Stage I to 58% for Stage IVA-B. The results achieved by the 2070 patients treated by radiotherapy alone were almost identical to that of the whole series, the distant failure-free rate among patients with locoregional control was 89% for Stage I-II and 75% for Stage III-IVB. The 860 patients (32%) staged with magnetic resonance imaging achieved significantly better results than those staged by computed tomography, the overall survival being 93% vs. 83% for Stages I-II, and 72% vs. 63% for Stages III-IVB (p = 0.001). Conclusions: Treatment results for nasopharyngeal carcinoma have substantially improved in the modern era; future trials should be based on updated baseline results. Further reduction of distant failure is important for future breakthrough, particularly for patients with advanced disease

  11. Preliminary experimental results on studying possibility of variable mass liner (VML) formation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    The main objective of the present experiment was to study the formation process and initial stage of acceleration of a variable-mass plasma liner (VML). The method is based on magnetic acceleration of a liner with the mass reduced during such acceleration. The experiment was carried out on February 16 at VNIIEF. This report describes the results of measurements obtained in the experiment and preliminary analysis of the results characterizing operation of the test facility main units: helical EMG; 5-module disk EMG 400 mm in diameter (DEMG); ponderomotive unit (PU) with a cylindric condensed liner and a special tooth-cutoff. The first part of the report presents measurement results obtained on the VNIIEF`s diagnostic equipment that are compared with those obtained by American specialists on their diagnostic equipment. Information submitted by American specialists is included in part 2 of this report. The second part of the report presents preliminary computational-theoretic analysis of the main measured results describing operation of DEMG TL system in the experiment; experimental data are compared with theoretical ones obtained before and after the experiment. But more emphasis is placed on the data preliminary analysis indicating that in the experiment a variable mass liner is formed (VML or plasma bubble).

  12. Preliminary experimental results on studying possibility of variable mass liner (VML) formation

    International Nuclear Information System (INIS)

    The main objective of the present experiment was to study the formation process and initial stage of acceleration of a variable-mass plasma liner (VML). The method is based on magnetic acceleration of a liner with the mass reduced during such acceleration. The experiment was carried out on February 16 at VNIIEF. This report describes the results of measurements obtained in the experiment and preliminary analysis of the results characterizing operation of the test facility main units: helical EMG; 5-module disk EMG 400 mm in diameter (DEMG); ponderomotive unit (PU) with a cylindric condensed liner and a special tooth-cutoff. The first part of the report presents measurement results obtained on the VNIIEF's diagnostic equipment that are compared with those obtained by American specialists on their diagnostic equipment. Information submitted by American specialists is included in part 2 of this report. The second part of the report presents preliminary computational-theoretic analysis of the main measured results describing operation of DEMG TL system in the experiment; experimental data are compared with theoretical ones obtained before and after the experiment. But more emphasis is placed on the data preliminary analysis indicating that in the experiment a variable mass liner is formed (VML or plasma bubble)

  13. Phase II Study of Consolidation Chemotherapy After Concurrent Chemoradiation in Cervical Cancer: Preliminary Results

    International Nuclear Information System (INIS)

    Purpose: Our aim was to determine the efficacy of consolidation chemotherapy after concurrent chemoradiation (CCRT) using high-dose-rate brachytherapy in patients with locally advanced cervical carcinoma. Methods and Materials: Patients with cervical carcinoma (FIGO stage IB2-IVA) were treated with external beam radiation therapy to the whole pelvis (50.4 Gy) and high-dose-rate brachytherapy (24 Gy to point A). Cisplatin 60 mg/m2 (Day 1) and 5-fluorouracil 1000 mg/m2 (Days 1-5) were given every 3 weeks starting concurrently with the radiation and followed by 3 more cycles of consolidation for a total of 6 cycles. Results: Thirty patients (94%) received 3 more cycles of post-CCRT consolidation chemotherapy and were evaluable for the toxicity and efficacy of consolidation. The most common toxicities of Grade 2 or higher were nausea or vomiting (47%) and anemia (33%). Late complications of the rectum and bladder occurred in 13% and 6% of the patients, respectively. The clinical complete response rate was 87% (95% CI, 75%-99%). During a median follow-up of 27 months (range, 6-58 months), 5 patients (17%) had recurrence; the sites of failure were 3 (10%) inside the radiation field and 2 (7%) outside the radiation field. The estimated 3-year progression-free survival rate was 83% (95% CI, 67%-99%) and overall survival rate was 91% (95% CI, 79%-100%). Conclusions: Consolidation chemotherapy after CCRT is well tolerated and effective in patients with locally advanced cervical carcinoma. A prospective randomized trial to compare this treatment strategy with standard CCRT seems to be worthwhile

  14. Preliminary results of fast neutron treatments in carcinoma of the pancreas

    Science.gov (United States)

    Gahbauer, R.; Koh, K. Y.; Rodriguez-Antunez, A.; Jelden, G. L.; Turco, R. F.; Horton, J.; Bukowski, R.; Reimer, R.; Blue, J.; Roberts, W.

    1980-01-01

    A group of 30 patients with adenocarcinoma of the pancreas including some patients with very advanced disease, were treated with the so-called mixed beam modality employing photon treatments three times per week and neutron treatments twice a week. Two hundred Rads or equivalent Rads (RBE 3.3) were given in daily fractions aiming at a total dose of 6000 Rads in 6 to 8 weeks. The treatments were well tolerated and significant palliation was achieved in 26 to 30 cases. Twelve months survival was 33 percent with a median survival of 7 months or 210 days. Treatment techniques and localization procedures are discussed.

  15. Preliminary results of centralized HER2 testing in ductal carcinoma in situ (DCIS): NSABP B-43

    Science.gov (United States)

    Siziopikou, Kalliopi P.; Anderson, Stewart J.; Cobleigh, Melody A.; Arthur, Douglas W.; Zheng, Ping; Mamounas, Eleftherios P.; Pajon, Eduardo R.; Behrens, Robert J.; Eakle, Janice F.; Leasure, Nick C.; Atkins, James N.; Polikoff, Jonathan A.; Seay, Thomas E.; McCaskill-Stevens, Worta J.; Rabinovitch, Rachel; Costantino, Joseph P.; Wolmark, Norman

    2016-01-01

    NSABP B-43 is the first prospective, randomized phase III multi-institution clinical trial targeting high-risk, HER2-positive DCIS. It compares whole breast irradiation alone with WBI given concurrently with trastuzumab in women with HER2-positive DCIS treated by lumpectomy. The primary aim is to determine if trastuzumab plus radiation will reduce in-breast tumor recurrence. HER2-positive DCIS was previously estimated at >50 %, occurring primarily in ER-negative, comedo-type DCIS of high nuclear grade. There has been no documented centralized multi-institutional HER2 analysis of DCIS. NSABP B-43 provides a unique opportunity to evaluate this in a large cohort of DCIS patients. Patients undergoing lumpectomy for DCIS without evidence of an invasive component are eligible. A central review of each patient’s pure DCIS lesion is carried out by immunohistochemistry analysis. If the lesion is 2+, FISH analysis is performed. Patients whose tumors are HER2 3+ or FISH-positive are randomly assigned to receive two doses of trastuzumab during WBI or WBI alone. NSABP B-43 opened 11/9/08. As of 7/31/2013, 5,861 patients have had specimens received centrally, and 5,645 of those had analyzable blocks; 1,969 (34.9 %) were HER2 positive. A total of 1,428 patients have been accrued, 1,137 (79.6 %) of whom have follow-up information. The average follow-up time for the 1,137 patients is 23.3 months. No grade 4 or 5 toxicity has been observed. In NSABP B-43 the HER2-positive rate for pure DCIS among patients undergoing breast-preserving surgery is 34.9 %, lower than the previously reported rate. No trastuzumab-related safety signals have been observed. Interest in this trial has been robust. PMID:24202240

  16. Comparison of abdominopelvic CT results and findings at second-look laparotomy in ovarian carcinoma patients

    International Nuclear Information System (INIS)

    Restaging in epithelial ovarian carcinoma after primary therapy has proven difficult by standard noninvasive methods and commonly requires second-look laparotomy. In the authors' study to date preoperative abdominopelvic CT (CBT) results and operative findings have been compared in 24 patients (25 studies) with ovarian adenocarcinoma currently clinically free of disease originally graded as FIGO stage III or IV, except for one patient with stage IC, undergoing second-look laparotomy to determine tumor status. There were ten true-negative, three false-negative, 12 true-positive, and no false-positive CBTs. Negative studies were associated with positive findings at laparotomy, including microscopic foci, in only 12% of all cases; thus, CBT in the series has shown a better correlation with surgery than in previous studies. Currently the authors are combining monoclonal antibody scanning with the CBT results with the goal of possibly avoiding second-look surgery in certain patients

  17. Nucleon resonance decay by the $K^{0} \\sum^{+}$ channel: Preliminary results

    Indian Academy of Sciences (India)

    S V Shende; R Castelijns; J C S Bacelar; H Löhner; J Messchendorp; CBELSA/TAPS Collaboration

    2006-05-01

    The strange meson production on a proton target in the $K^{0} \\sum^{+}$ channel is sensitive to nucleon resonance contributions. The $K^{0}$ production on a deuteron target can provide information on the hyperon-nucleon final-state interaction. The experiments $ p → K^{0} \\sum^{+}$ and $ d → K^{0} \\sum^{+} n$ have been carried out at the ELSA facility at Bonn. In this paper, we report the preliminary results of both experiments.

  18. Preliminary Results of the Echo-Seeding Experiment ECHO-7 at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, D.; Colby, E.; Ding, Y.; Dunning, M.; Frederico, J.; Gilevich, S.; Hast, C.; Jobe, K.; McCormick, D.; Nelson, J.; Raubenheimer, T.O.; Soong, K.; Stupakov, G.; Szalata, Z.; Walz, D.; Weathersby, S.; Woodley, M.; /SLAC; Corlett, J.; Qiang, J.; Penn, G.; Prestemon, S.; /LBL, Berkeley /LPHE, Lausanne

    2010-06-15

    ECHO-7 is a proof-of-principle echo-enabled harmonic generation FEL experiment in the Next Linear Collider Test Accelerator (NLCTA) at SLAC. The experiment aims to generate coherent radiation at 318 nm and 227 nm, which are the 5th and 7th harmonic of the infrared seed laser. In this paper we present the preliminary results from the commissioning run of the completed experimental setup which started in April 2010.

  19. First steps of laparoscopic surgery in Lubumbashi: problems encountered and preliminary results

    OpenAIRE

    Arung, Willy; Dinganga, Nathalie; Ngoie, Emmanuel; Odimba, Etienne; Detry, Olivier

    2015-01-01

    For many reasons, laparoscopic surgery has been performed worldwide. Due to logistical constraints its first steps occurred in Lubumbashi only in 2008. The aim of this presentation was to report authors’ ten-month experience of laparoscopic surgery at Lubumbashi Don Bosco Missionary Hospital (LDBMH): problems encountered and preliminary results. The study was a transsectional descriptive work with a convenient sampling. It only took in account patients with abdominal surgical condition who co...

  20. Facial emotional recognition in schizophrenia: preliminary results of the virtual reality program for facial emotional recognition

    OpenAIRE

    Teresa Souto; Alexandre Baptista; Diana Tavares; Cristina Queirós; Marques António

    2013-01-01

    BACKGROUND: Significant deficits in emotional recognition and social perception characterize patients with schizophrenia and have direct negative impact both in inter-personal relationships and in social functioning. Virtual reality, as a methodological resource, might have a high potential for assessment and training skills in people suffering from mental illness. OBJECTIVES: To present preliminary results of a facial emotional recognition assessment designed for patients with schizophrenia,...

  1. The evaluation of GL impact in Physical sciences using bibliometric indicators : preliminary results

    OpenAIRE

    Di Cesare, Rosa; GreyNet, Grey Literature Network Service

    1994-01-01

    A bibliometric study of the Italian grey literature in SIGLE database. Preliminary results. Given the increasing importance of Grey Literature (GL) for the information and documentation field, it is essential to apply a bibliometric analysis similar to the one widely used for the conventional literature. Study objectives: 1) impact evalutation of grey literature in physical sciences; and 2) differentiation between scientific and non scientific grey literature documents in the same discipline,...

  2. The RPC-based IFR system at BaBar experiment preliminary results

    CERN Document Server

    Piccolo, D; Bagnasco, S; Baldini, R; Band, H R; Bionta, R; Buzzo, A; Calcaterra, A; Cavallo, N; Contri, R; Crosetti, G; De Nardo, Gallieno; De Sangro, R; Fabozzi, F; Falciai, D; Finocchiaro, G; Gatto, C; Johnson, J; Lista, L; Lo Vetere, M; Macri, M; Monge, R; Palano, A; Paolucci, P; Passaggio, S; Patrignani, C; Patteri, P; Peruzzi, I; Piccolo, M; Robutti, E; Santroni, A; Sciacca, C; Wright, D; Yu, Z; Zallo, A

    2002-01-01

    The IFR system is a RPC-based detector used to identify muons and neutral hadrons in the BaBar experiment at PEP II machine in SLAC. The RPC system can be used to reconstruct the trajectory of muons, pions and neutral hadrons interacting in the iron of the IFR. The different range and hit pattern allow to discriminate different particles crossing the IFR. An overview of the system design and the preliminary results on the IFR performances are reported.

  3. Preliminary results from a passive seismic array over the Chicxulub impact structure in Mexico

    OpenAIRE

    P. K. H. Maguire; Mackenzie, G D; Denton, P.; Trejo, A.; Rainer Kind

    1998-01-01

    A passive, 20-element, short-period (1 Hz) and broadband seismic array was deployed over the Chicxulub impact structure for c. 100 days in early 1996. The principal objective was to study the shear-wave anisotropy associated with the structure; in particular, to determine the presence (or absence= of radial symmetry which will allow comment on the time variance of that anisotropy. A total of 15 teleseismic, 75 regional, and 100 local events were recorded. Preliminary results from studies of t...

  4. Parallel Guided Local Search and Some Preliminary Experimental Results for Continuous Optimization

    Directory of Open Access Journals (Sweden)

    Nasser Tairan

    2014-02-01

    Full Text Available This paper proposes a Parallel Guided Local Search (PGLS framework for continuous optimization. In PGLS, several guided local search (GLS procedures (agents are run for solving the optimization problem. The agents exchan ge information for speeding up the search. For example, the information exchanged could be kno wledge about the landscape obtained by the agents. The proposed algorithm is applied to co ntinuous optimization problems. The preliminary experimental results show that the algo rithm is very promising .

  5. Neolithic plant use in the western Mediterranean region: preliminary results from the AGRIWESTMED Project

    OpenAIRE

    Peña-Chocarro, Leonor; Pérez Jordá, Guillem; Morales Mateos, Jacob; Zapata, Lydia

    2013-01-01

    This contribution focuses on the preliminary results of the AGRIWESTMED project which focuses on the archaeobotanical analyses of early Neolithic sites in the western Mediterranean region (both in Iberia and in northern Morocco). A large number of sites has been studied producing an interesting dataset of plant remains which places the earliest examples of domesticated plants in the second half of the 6th millennium cal BC. Plant diversity is high as it is shown by the large number o...

  6. Preliminary results and analyses of using IGS GPS data to determine global ionospheric TEC

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Using the spherical harmonic (SH) function model and the dual frequency GPS data of 139 International GPS Service (IGS) stations for July 15 of 2000, the global ionospheric total electron content (TEC) is calculated and the basic method is investigated. Here, preliminary results are reported and the problems and difficulties to be solved for using GPS data to determine the global ionospheric TEC are discussed.

  7. Holocene evolution and sedimentation rate of Alikes Lagoon, Zakynthos island, Western Greece – preliminary results

    OpenAIRE

    P. Avramidis; N. Kontopoulos

    2009-01-01

    In the present study we present preliminary results of Zakynthos Alikes lagoon, which is one of the most seismically active regions of Greece. In order to estimate – interpret the Holocene evolution of the area and to reconstruct the palaeonvironmental changes, we based on the data of a 21 m sediment core. Sediment types, structure, colour, as well as contact depths and bed characteristics, were recorded in the field. Standarised sedimentological analysis were carried out, on 46 samples inclu...

  8. Investigation of polarized-proton target materials by differential calorimetry: preliminary results

    International Nuclear Information System (INIS)

    A simple differential calorimeter was designed and operated for an investigation of the thermodynamic properties of polarized target materials. The calibration and use of the calorimeter are discussed, after a brief exposition of our motivation for this work. The results of a preliminary study of target materials is presented with emphasis on the relevance of the glass state to dynamic polarization in chemically-doped targets

  9. Results of salvage radiotherapy after inadequate surgery in invasive cervical carcinoma patients: A retrospective analysis

    International Nuclear Information System (INIS)

    Purpose: To evaluate the results of salvage radiotherapy (RT) after inadequate surgery in patients with invasive carcinoma of the cervix. Methods and Materials: Between 1996 and 2001, 105 invasive cervical carcinoma patients were treated at our center with external beam RT with or without intracavitary RT after having undergone total/subtotal hysterectomy at outside institutions. Results: The median follow-up was 34 months. The gap between surgery and RT was 23-198 days (median, 80). Clinically visible residual disease was present in 81 patients (77.1%). Total hysterectomy had been done in 82 patients (78%) and subtotal hysterectomy in 23 patients (22%). The 5-year overall survival, disease-free survival, and pelvic control rates of all patients were 55.2%, 53.3%, and 72.4%, respectively. On univariate analysis, older age, total hysterectomy, hemoglobin level >10 g% before RT, nonsquamous histologic type, use of intracavitary RT, a shorter gap between surgery and RT, and the absence of, or a small volume of, residual disease favorably affected the outcome. The 5-year actuarial rate of late toxicity (Radiation Therapy Oncology Group Criteria) was 19% in the rectum, 4.8% in the bladder, 24.8% in the skin, and 14.3% in the small intestine. Conclusions: Inadequate and inappropriate surgery in invasive cervical cancer with resulting gross residual disease is common in India. Factors such as the use of intracavitary RT, the correction of anemia, and a shorter gap between surgery and RT will enable postoperative RT to achieve acceptable results with minimal morbidity

  10. Most significant preliminary results of the probabilistic safety analysis on the Juragua nuclear power plant

    International Nuclear Information System (INIS)

    Since 1990 the Group for PSA Development and Applications (GDA/APS) is working on the Level-1 PSA for the Juragua-1 NPP, as a part of an IAEA Technical Assistance Project. The main objective of this study, which is still under way, is to assess, in a preliminary way, the Reactor design safety to find its potential 'weak points' at the construction stage, using a eneric data base. At the same time, the study allows the PSA team to familiarize with the plant design and analysis techniques for the future operational PSA of the plant. This paper presents the most significant preliminary results of the study, which reveal some advantages of the safety characteristics of the plant design in comparison with the homologous VVER-440 reactors and some areas, where including slight modifications would improve the plant safety, considering the level of detail at which the study is carried out. (author). 13 refs, 1 fig, 2 tabs

  11. Protocol and result of neoadjuvant chemotherapy for locally advanced esophageal carcinoma

    International Nuclear Information System (INIS)

    The protocol and result were described of chemotherapy and radiotherapy for locally advanced esophageal carcinoma, especially for A3 stage one with metastasis at neighboring tissues such as aorta, trachea and bronchia. Chemotherapy was done with 5-FU and CDDP and radiotherapy, with 30 Gy/15 fx/3 wk. Double contrast roentgenography, dynamic CT and MRI were performed to follow the process. The efficacy rate was 55.0% with 4 CR and 7 PR in 20 cases. Three CR patients survived at present. Major adverse effects were leukopenia and thrombocytopenia, of which grade 4 were found in 14 and 12% cases, respectively. Low-dose FP therapy might be useful for lowering the adverse effects and for elevating the efficacy rates. (K.H.)

  12. Results of radiotherapy for carcinomas of the floor of the mouth

    International Nuclear Information System (INIS)

    Results and problems of radiotherapy for carcinomas of the floor of the mouth were analyzed for 54 patients treated from 1967 through 1995. Twenty-six of the 52 patients who received external irradiation were treated also with brachytherapy. Five-year cause-specific survival rates were 89% in stage I, 85% in stage II, 64% in stage III, and 63% in stage IV. The survival rate was 57% for patients with clinically positive nodes but was 88% in node-negative patients. Surgical treatment was performed in seven patients (13%) with late complications, such as osteoradionecrosis and severe soft tissue ulcers. Multiple primary cancers arose in 12 of 54 (22%) patients. Although radiotherapy was confirmed to be an excellent procedure because of its high curability and preservation of function and appearance, ways must be found improve survival in node-positive patients, reduce complications, and early detect secondary cancers at an earlier stage. (author)

  13. Endogenous sex steroids and risk of cervical carcinoma: results from the EPIC study

    DEFF Research Database (Denmark)

    Rinaldi, Sabina; Plummer, Martyn; Biessy, Carine;

    2011-01-01

    Epidemiologic data and animal models suggest that, despite the predominant role of human papillomavirus infection, sex steroid hormones are also involved in the etiology of invasive cervical carcinoma (ICC).......Epidemiologic data and animal models suggest that, despite the predominant role of human papillomavirus infection, sex steroid hormones are also involved in the etiology of invasive cervical carcinoma (ICC)....

  14. Low Dose BCG Regimen in T1 Transitional Cell Carcinoma of the Bladder: Long Term Results

    International Nuclear Information System (INIS)

    BCG has been used for more than 30 years and is currently the most effective agent for non-muscle invasive bladder cancer therapy after transurethral resection. The high-grade T1 lesion treated by transurethral resection alone is reported to progress to muscle invasion in 30% to 50% of the patients. Until now, optimal treatment schedule and optimal dose have not been defined as the toxicity related to BCG therapy is significant. In this study we tried to evaluate the efficacy and toxicity of 60 mg intravesical BCG (Pasteur strain) therapy in patients with T1 transitional cell carcinoma of the bladder. Patients and Methods: From January 2000 till December 2007, 74 patients with single T1 transitional cell carcinoma (TCC) of the urinary bladder (grade 3 in 24 patients and grade 2 in 50 patients) were treated by complete transurethral resection followed by a 6-weeks course of 60 mg BCG intravesically. Follow-up ranged from 26- 96 months with median of 61 months. Results: Nine patients (12.1%) exhibited recurrence with muscle invasion after 6-18 months (5 with grade 3 tumors and 4 with grade 2), all were subjected to radical cystectomy and urine diversion. Whereas 19 patients (29.2%) showed recurrent T1 tumor after 16-45 months (7 with grade 3 tumors and 12 with grade 2) and were treated by TUR-T followed by a second 6-weeks course of 60 mg BCG intravesically. Recurrence index was 0.82/100 patients/month and the median tumor free period was 20 months. Regarding toxicity; irritative symptoms occurred in 24% of patients, fever in 9%, microscopic hematuria in 14%; which appeared to be significantly low when compared with the rates reported for higher doses of BCG. Conclusion: Intravesical therapy of 60 mg BCG is effective in prophylaxis against recurrence and progression of T1 TCC of the bladder. Decreasing the dose resulted

  15. Radiation Therapy Results of Invasive Cervical Carcinoma Found After Inappropriate Hysterectomy

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Doo Ho; Kim, Eun Seog; Nam, Kae Hyun; Huh, Seung Jae [Soonchunhyang University College of Medicine, Seoul (Korea, Republic of)

    1996-09-15

    Purpose : Hysterectomy without lymph node dissection was considered an inadequate treatment method for invasive uterine cervix cancer. Usually the procedure was performed inadvertently on patients who were thought to have benign or premalignant conditions preoperatively. We analysed radiotherapy results of such patients to evaluate survival rates, failure patterns and prognostic factors according to various conditions. Methods and Materials : Sixty one patients undergoing hysterectomy in the presence of invasive cervical carcinoma were reviewed retrospectively. Preoperative diagnosis were carcioma in situ (38 cases), severe dysplasia(2), myoma(6), uterine bleeding (4), uterine prolapse (2), and early invasive cervix cancer (10) (One patient had myoma and carcinoma in situ coincidently). Patients received postoperative megavoltage radiotherapy form August 1985 to December 1993, and minimum follow-up period was 24 months. Eight patients reveived ICR only, 6 patients ICR and external radiation, and 47 patients received external radiation therapy only. Results : Overall 5-year survival rate and relapse-free survival rate were 83.8%, 86.9% respectively. For patients with retrospective stage IA, IB, IIB (gross residual after surgery), and vaginal cuff recurrence were 90.9%, 88.8%, 38.4%, and 100% respectively. There were 8 cases of treatment failure, most of them (5/8) were in patients with gross residual disease, other patients were full thickness involvement of cervix wall (2/8) except one. Patients with early vaginal cuff recurrence and microinvasive cervical cncer (stage IA) had no treatment related failure. Prognostic factors affecting survival by univariate analysis were status of residual disease, tumor histology and retrospective stage. Conclusion : Adjuvant radiotherapy appeared to be effective treatment method for patients with presumed stage IA, IB and early local recurrent disease after inadvertent hysterectomy. Survivals for patients with gross disease

  16. Accelerated radiotherapy for T1, 2 glottic carcinoma: analysis of results with KI-67 index

    International Nuclear Information System (INIS)

    Purpose: Hyperfractionated and accelerated radiotherapy without a split was performed to improve the local control probability of early glottic carcinomas. We analyzed the results of this regimen by using the Ki-67 index. Methods and Materials: Over a 12-year period, 85 T1N0M0 glottic cancers and 50 T2N0M0 glottic cancers were treated with conventional fractionation (CF) from 1984 to 1989 and with accelerated fractionation (AF) since 1990. The CF program consisted of five daily fractions of 2 Gy per week, for a total of 64 Gy. The AF program consisted of 1.72 Gy per fraction, two fractions per day, 5 days a week, for a total of 55 or 58 Gy. The specimens, taken before radiotherapy, were immunohistochemically stained with anti-Ki-67 antibody. Results: The 5-year local control probability for T1 tumors was 79.6 ± 6.9% with CF treatment, whereas with AF it was 86.9 ± 5.6%. For T2 tumors it was 62.7 ± 12.2% with CF, whereas it was 74.7 ± 7.8% with AF. The difference between CF and AF did not reach the point of statistical significance. However, when T1 tumors had a Ki-67 index lower than 50%, the local control rate achieved with AF was significantly better than that with CF (p = 0.018). When the tumors had a Ki-67 index that was 50% or more, there was no difference in the local control rate between CF and AF, whether they were T1 or T2. The peak mucosal reactions at the larynx and/or hypopharynx were much more severe and appeared at smaller doses and earlier in AF than in CF. The patients with AF showed no severe late complications. Conclusions: AF could not obtain statistically significant improvement in local control probability of T1 or T2 glottic carcinomas

  17. Efficacy of sorafenib on metastatic renal cell carcinoma in Asian patients: Results from a multicenter study

    Directory of Open Access Journals (Sweden)

    Shen Yijun

    2009-07-01

    Full Text Available Abstract Background The effects of sorafenib in the treatment of advanced renal cell carcinoma (RCC have been confirmed in an international collaborative phase III trial. This study aims to confirm similar efficacy and treatment-induced toxicities of sorafenib in the treatment of metastatic RCC in ethnic Chinese patients. Methods Ninety-eight consecutive and non-selected patients with pathologically confirmed metastatic RCC were treated according to an institutional treatment protocol. All patients were treated with 400 mg of sorafenib orally twice daily on a continuous basis until disease progression or intolerance to treatment occurred. Dose reduction to 400 mg once daily was required if grade 3 or 4 toxicities occurred. All patients except for 7 received nephrectomy in the course of their disease. All patients were assessed for tumor response, progression-free survival (PFS, overall survival (OS, and treatment-induced toxicities. Results The median follow-up time was 76 weeks (range 2–296 weeks for the entire group of patients. Radiologically confirmed complete response (CR, partial response (PR, stable disease (SD of more than 4 months, and disease progression as best objective responses were observed in 1 (1%, 23 (23.5%, 62 (63.3%, and 12 (12.2% patients, respectively. The tumor control rate (CR+PR+SD of >4 months was 87.8%. The 1-year estimated PFS and OS were 58.4% and 64.6%, respectively. The median progression-free survival (PFS time was 60 weeks (95% CI 41–79; and the median overall survival (OS time was not reached with a follow-up of 76 weeks. Reduction of sorafenib dose was required in 26 patients who developed grade 3 or 4 treatment-cause adverse-effects. An additional 9 patients discontinued sorafenib treatment due to severe adverse-effects. No grade 5 toxicity occurred. Multivariate analysis revealed that independent predictive factors for tumor response to sorafenib treatment included ECOG status, presence of lymph node

  18. Squamous cell carcinoma of the oropharynx--an analysis of treatment results in 289 consecutive patients

    International Nuclear Information System (INIS)

    In this retrospective study the results of primary and salvage treatment of oropharyngeal carcinoma were evaluated. A total of 289 consecutive patients (103 females and 186 males) were included in the study. Most tumours originated in the tonsil area (58%) and comprised stages I 8%, II 19%, III 46% and IV 28%. The primary treatment was delivered with curative intent in 276 cases (96%). Of these, 266 received primary radiotherapy. The median radiation dose was 62 Gy, given as laterally opposed fields to the primary tumour and bilateral neck. Eight patients were treated with primary surgery and two with chemotherapy as part of a curatively intended treatment programme including radiotherapy. Six patients received palliative treatment, and seven were not treated at all. Out of 276 tumours treated with curative intent, 173 reappeared; 72% recurred in T position, 38% in N position, and 12% at distant metastatic sites, some in combination. Salvage surgery was possible in 52 patients, and 24 treatments were successful. Salvage radiotherapy or cryotherapy was used in 22 patients and 4 were controlled. For the entire group, the 5-year locoregional tumour control, disease-specific survival and overall survival rates were 38%, 44% and 31%, respectively. For patients treated with curative intent, clinical T- and N-stage, stage, tumour size, gender, age, and pretreatment haemoglobin were significant prognostic parameters in a univariate analysis. The Cox multivariate analysis showed that T-stage, N-stage and gender were independent prognostic factors. It is concluded that T-stage, N-stage and gender are significant independent prognostic factors. The primary control of the carcinoma in the T-position is crucial for overall success, but salvage surgery is found to have a favourable success rate in patients suitable for relapse treatment

  19. Squamous cell carcinoma of the oropharynx--an analysis of treatment results in 289 consecutive patients

    Energy Technology Data Exchange (ETDEWEB)

    Johansen, L.V.; Grau, C.; Overgaard, J. [Aarhus Univ. Hospital (Denmark). Dept. of Experimental Clinical Oncology

    2001-01-01

    In this retrospective study the results of primary and salvage treatment of oropharyngeal carcinoma were evaluated. A total of 289 consecutive patients (103 females and 186 males) were included in the study. Most tumours originated in the tonsil area (58%) and comprised stages I 8%, II 19%, III 46% and IV 28%. The primary treatment was delivered with curative intent in 276 cases (96%). Of these, 266 received primary radiotherapy. The median radiation dose was 62 Gy, given as laterally opposed fields to the primary tumour and bilateral neck. Eight patients were treated with primary surgery and two with chemotherapy as part of a curatively intended treatment programme including radiotherapy. Six patients received palliative treatment, and seven were not treated at all. Out of 276 tumours treated with curative intent, 173 reappeared; 72% recurred in T position, 38% in N position, and 12% at distant metastatic sites, some in combination. Salvage surgery was possible in 52 patients, and 24 treatments were successful. Salvage radiotherapy or cryotherapy was used in 22 patients and 4 were controlled. For the entire group, the 5-year locoregional tumour control, disease-specific survival and overall survival rates were 38%, 44% and 31%, respectively. For patients treated with curative intent, clinical T- and N-stage, stage, tumour size, gender, age, and pretreatment haemoglobin were significant prognostic parameters in a univariate analysis. The Cox multivariate analysis showed that T-stage, N-stage and gender were independent prognostic factors. It is concluded that T-stage, N-stage and gender are significant independent prognostic factors. The primary control of the carcinoma in the T-position is crucial for overall success, but salvage surgery is found to have a favourable success rate in patients suitable for relapse treatment.

  20. Results of electron beam therapy using intra-oral cone for carcinoma of the oral tongue

    International Nuclear Information System (INIS)

    Retrospective analyses were performed to evaluate the therapeutic efficacy of intra-oral cone (IOC) radiation therapy for carcinoma of the oral tongue, especially about its faculty of local control and complications. Thirty-nine patients with squamous cell carcinoma of the oral tongue were treated with IOC radiation therapy alone or in combination with external irradiation. IOC radiation therapy was given not only for T1 and T2, but also for T3 tumors. Hypofractionation was used for IOC radiation therapy. The 2 year local control rates, including surgical salvage, for T1, T2, T3 and T4 were 100%, 73.3%, 40% and 0%, respectively. The 5 year actuarial survival rates for Stage I, II, III and IV were 100%, 65.3%, 35.4% and 0%, respectively. The incidences of radiation complications, i.e. soft tissue ulceration and osteoradionecrosis, were 42.9% and 2.9%, respectively. It is suggested that relatively high rate of soft tissue ulceration was due to hypofractionation. We have found summated Gy dosage correlate better than summated TDF values for both local control and complication rates for IOC radiation therapy with hypofractionation method. If complete disappearance of primary tumor was not achieved after IOC radiation therapy of 30 Gy, it is not reasonable to add external irradiation. Surgical resection of the residual tumor is the treatment of choice in view of local control and complication. These results suggest that selection of the cases suitable for IOC is important and re-evaluation of the adequate fractionation scheme for IOC is necessary. (author)

  1. Ion currents and energies in reactive low-voltage ion plating: preliminary results

    Science.gov (United States)

    Edlinger, Johannes P.; Pulker, Hans K.

    1990-12-01

    Reactive Low-Voltage Ion Plating (RLVIP) is a plasma-assisted evaporation process that produces anorganic oxide- and nitride films with a closed microstructure. in order to better understand the process and the resulting film properties a BALZERS PPM 400 Plasmamonitor, a combination of a quadrupole mass filter and an energy selective ion optics, has been used to study the relative abundancies and energy distributions of the ions impinging on the growing film in the RLVIP process. The device is discussed and preliminary results are presented: The plasma is anisotropic. Surprisingly it contains ions with higher energies than expected from the self-bias potential.

  2. [Preliminary results of lymphatic chemotherapy in the treatment of rectal cancer].

    Science.gov (United States)

    Narvuzov, S N; Zkbarov, E T; Abduzhabborov, S B; Khakimov, A M; Bobokulov, Kh B; Sidikov, U R

    2004-03-01

    Preliminary results of treatment of 28 patients with cancer recti, in whom lymphatic chemotherapy was applied and operative intervention as well, were studied. The results of treatment in control group, consisting of 28 patients, to whom neoadjuvant systemic chemotherapy was conducted, are adduced. Comparative analysis performed have shown that general toxic signs occurred three times lesser in patients of the main group, than in a control one; the postoperative complications was two times lesser. In one-year follow-up in the main group the recurrences and metastases were absent, in a control group the tumor recurrence had occurred in 3 (10%) of patients. PMID:15154248

  3. Radon and radon daughters' concentration in spring and wells waters from Presidente Prudente: preliminary results

    International Nuclear Information System (INIS)

    This work presents the preliminary results about the concentration of radon and radon daughters in wells and springs water from Presidente Prudente. Six water samples were studied: three from well-water, two from springs water and one from potable water. For the determination of α-activity the samples were placed inside plastic containers where the CR-39 tracks detectors were outside the water. The track density of α-particles were measured by using optical microscopy. The results show that one sample from well-water presented higher concentration of radon and radon daughters than the other samples. (author)

  4. Preliminary results of the large experimental wind turbine phase of the national wind energy program

    Science.gov (United States)

    Thomas, R. L.; Sholes, T.; Sholes, J. E.

    1975-01-01

    The preliminary results of two projects in the development phase of reliable wind turbines designed to supply cost-competitive electrical energy were discussed. An experimental 100 kW wind turbine design and its status are first reviewed. The results of two parallel design studies for determining the configurations and power levels for wind turbines with minimum energy costs are also discussed. These studies predict wind energy costs of 1.5 to 7 cents per kW-h for wind turbines produced in quantities of 100 to 1000 per year and located at sites having average winds of 12 to 18 mph.

  5. Some preliminary photometric results of QSOs useful for the link between future Gaia CRF and ICRF

    Science.gov (United States)

    Damljanovic, G.; Taris, F.; Boeva, S.

    2015-08-01

    Gaia was launched in December 2013 as cornerstone mission of the European Space Agency (ESA). It is going to map the entire sky (over one billion stars) and more than 500,000 quasars (QSOs); all objects with apparent V band magnitudes in the range 5.6 Serbia). Some preliminary photometric results are presented as a part of astrophotometric and astrophysical investigations of ERS in the framework of the reference systems. Also, some photometric results following from the data obtained by using the TJO (Telescopi Juan Oro, D = 0.8 m) in OAdM (Observatori Astronomic del Montsec, Spain) are presented.

  6. Polimorfismi nei geni metabolici come fattori dirischio per il carcinoma gastrico (GC: risultati preliminari di uno studio caso-controllo

    Directory of Open Access Journals (Sweden)

    S. Boccia

    2003-05-01

    Full Text Available

    Obiettivi: valutare le frequenze dei principali geni metabolici in un campione di casi di GC (Carcinoma Gastrico e di controlli, per determinare se esiste un’associazione con il rischio di GC, e considerare le possibili associazioni tra i genotipi studiati ed alcuni parametri clinico-patologici.

    Metodi: è stato condotto uno studio caso-controllo ospedaliero, tra novembre 1999 e maggio 2003 reclutando 48 pazienti con diagnosi di adenocarcinoma gastrico sottoposti a gastrectomia, e 48 controlli appaiati per sesso ed età presso il Policlinico Universitario “A. Gemelli” in Roma. Per genotipizzare gli individui rispetto ai geni GSTM1, NAT2, SULT1A1, CYP1A1, CYP2E1 (5’ flanking e introne 6, è stata usata la tecnica della PCR con analisi del profilo dei frammenti di restrizione (PCR-RFLP. L’analisi statistica ha previsto l’impiego di test non parametrici e della regressione logistica.

    Risultati: le frequenze dei polimorfismi nei geni metabolici sono risultate in alcuni casi differenti nei casi rispetto ai controlli sebbene non si evidenzi una differenza statisticamente significativa. In particolare il genotipo GSMT1 null è più elevato nei pazienti rispetto ai controlli (63.8% vs. 51% e gli individui NAT2 acetilatori lenti risultano più frequenti nei casi rispetto ai controlli (69.6% vs. 57.45%. L’istotipo diffuso di GC è associato significativamente ai pazienti eterozigoti per l’allele SULT1A1 (c_= 8.216; p= 0.018, ed i pazienti NAT2 acetilatori lenti tendono ad avere un grading tumorale alto (c_= 7.425; p= 0.006.

    Conclusioni: i risultati preliminari di questo studio evidenziano associazioni tra alcuni genotipi metabolici e parametri clinico-patologici, che se confermati potrebbero permettere di identificare sottogruppi con prognosi più sfavorevole di GC da indirizzare preventivamente verso trattamenti specifici.

  7. 75 FR 65449 - Stainless Steel Bar From India: Extension of Time Limit for the Preliminary Results of the...

    Science.gov (United States)

    2010-10-25

    ... International Trade Administration Stainless Steel Bar From India: Extension of Time Limit for the Preliminary... Revocation in Part, 75 FR 15679 (March 30, 2010). The preliminary results for this administrative review are... duty order on stainless steel bar from India covering the period February 1, 2009, through January...

  8. Hybridization among wild boars, local breeds and commercial breeds - preliminary results

    DEFF Research Database (Denmark)

    Iacolina, Laura; Bakan, Jana; Cubric-Curik, Vlatka;

    2016-01-01

    . Hybridization with the domestic pig is known to occur in Europe, however the degree and extent of the phenomenon is not fully understood yet. Introgression is considered to be a treat to biodiversity and could lead to loss of local adaptation or introgression in the wild population of human selected genes. A...... gradients in variability levels among the analysed wild and domestic populations. This preliminary results will be further investigated to address the possible presence of hybrid zone(s) in Europe and the possible implications for conservation and management of both wild populations and local pig breeds, as...

  9. UAS Integration into the NAS: iHTL: DAA Display Evaluation Preliminary Results

    Science.gov (United States)

    Fern, Lisa; Rorie, Conrad; Shively, Jay

    2014-01-01

    The integrated human-in-the-loop (iHITL) simulation examined the effect of four different Detect-and-Avoid (DAA) display concepts on unmanned aircraft system (UAS) pilots' ability to maintain safe separation. The displays varied in the type and amount of guidance they provided to pilots. The study's background and methodology are discussed, followed by a presentation of the preliminary 'measured response' data (i.e., pilots' end-to-end response time in reacting to traffic alerts on their DAA display). Results indicate that display type had moderate to no affect on pilot measured response times.

  10. MISSE-7 MESA Miniaturized Electrostatic Analyzer - Ion Spectra Analysis Preliminary Results

    Science.gov (United States)

    Enloe, C. L.; Balthazor, R. L.; McHarg, M. G.; Clark, A. L.; Waite, D.; Wallerstein, A. J.; Wilson, K. A.

    2011-12-01

    The 7th Materials on the International Space Station Experiment (MISSE-7) was launched in November 2009 and retrieved on STS-134 in April 2011. One of the onboard experiments, the Miniaturized Electrostatic Analyzer (MESA), is a small low-cost low-size/weight/power ion and electron spectrometer that was pointed into ram during the majority of the time onboard. Over 800 Mb of data has been obtained by taking spectra every three minutes on-orbit. The data has been analyzed with a novel "parameterizing the parameters" method suitable for on-orbit data analysis using low-cost microcontrollers. Preliminary results are shown.

  11. Pyrolysis process for treatment of automobile shredder residue: preliminary experimental results

    Energy Technology Data Exchange (ETDEWEB)

    Galvagno, S.; Fortuna, F.; Cornacchia, G.; Casu, S.; Coppola, T.; Sharma, V.K. [ENEA C.R. Trisaia, AMB-TEIN-RIF Unit, Policoro (Italy)

    2001-03-01

    The main objective of the present research work is to evaluate both the process performances and characteristics of the products obtained from the treatment of automobile shredder residue (ASR) using pilot scale experimental pyrolysis plant operating under different load and varying process temperatures. ASR samples used for the treatment, solid and liquid by-products obtained and syngas produced were analysed both through on-line monitoring (gas) and laboratory analysis. Brief descriptions of the plant as well as the preliminary experimental results obtained are presented here. (Author)

  12. Preliminary Results of Ion Beam Extraction Tests on EAST Neutral Beam Injector

    Institute of Scientific and Technical Information of China (English)

    胡纯栋

    2012-01-01

    The neutral beam injection (NBI) system is one of the most important auxiliary plasma heating and current driving methods for fusion device. A high power ion beam of 3 MW with 80 keV beam energy in 0.5 s beam duration and a long pulse ion beam of 4 s with 50 keV beam energy ion beam extraction were achieved on the EAST neutral beam injector on the teststand. The preliminary results show that the EAST-NBI system was developed successfully on schedule.

  13. VNIIEF-ORNL Joint Plutonium Measurements with NMIS and Results of Plutonium Attributes Preliminary Evaluations

    International Nuclear Information System (INIS)

    Within the frameworks of TO No.007 between ORNL and VNIIEF on Nuclear Materials Identification System (NMIS) mastering at VNIIEF in July 2000 there had been finalized joint measurements, in which NMIS-technique equipment was used that had been placed at VNIIEF's disposal by ORNL, as well as VNIIEF-produced unclassified samples of fissile materials. In the report there are presented results of experimental data preliminary processing to obtain absolute values of some attributes used in plutonium shells measurements: values of their mass and thickness. Possibility of fissile materials parameters absolute values obtaining from measurement data essentially widens NMIS applicability to the tasks relevant to these materials inspections

  14. Preliminary results of Lean method implementation in a pathology lab from Northeastern Brazil

    Directory of Open Access Journals (Sweden)

    Josiane S. Quetz

    2015-02-01

    Full Text Available Oncologic care shows a growing and unmet demand, and requires the search for alternatives that allow the efficient use of limited resources, the building of autonomy, and the endeavour for continuous improvement of processes. In the present work, we present the implementation of Lean philosophy at a pathology laboratory of an oncology hospital. Among the preliminary results, we highlight the redefinition of the dynamics of the staff, and the physical reorganization of the area. Such important changes culminated in an expressive reduction of lead time, even with a significant increase in the monthly load of exams.

  15. Postmortem study of stable carbon isotope ratios in human cerebellar DNA: preliminary results

    International Nuclear Information System (INIS)

    It is observed that 13C/12C ratios in tissue specimens removed postmortem in the United States and Canada are significantly different from corresponding ratios in European specimens. On the basis of this information, measurements of carbon isotope ratios in DNA isolated from cerebella of native-born and European-born North Americans are in progress with the goal of estimating the average lifetime rate of DNA turnover in human neurons. Preliminary results from twenty postmortem examinations are consistent with the hypothesis that a significant proportion of human cerebellar DNA is renewed during the lifetime of an individual

  16. Preliminary Results from Small-Pixel CdZnTe and CdTe Arrays

    Science.gov (United States)

    Ramsey, B. D.; Sharma, D. P.; Meisner, J.; Austin, R. A.

    1999-01-01

    We have evaluated 2 small-pixel (0.75 mm) Cadmium-Zinc-Telluride arrays, and one Cadmium-Telluride array, all fabricated for MSFC by Metorex (Finland) and Baltic Science Institute (Riga, Latvia). Each array was optimized for operating temperature and collection bias. It was then exposed to Cadmium-109 and Iron-55 laboratory isotopes, to measure the energy resolution for each pixel and was then scanned with a finely-collimated x-ray beam, of width 50 micron, to examine pixel to pixel and inter-pixel charge collections efficiency. Preliminary results from these array tests will be presented.

  17. Preliminary results of mental workload and task engagement assessment using electroencephalogram in a space suit.

    Science.gov (United States)

    Rabbi, Ahmed F; Zony, Abongwa N; de Leon, Pablo; Fazel-Rezai, Reza

    2012-01-01

    In this paper, we present preliminary results of subject's mental workload and task engagement assessment in an experimental space suit. We have quantified the mental workload and task engagement based on changes in electroencephalogram (EEG). EEG signals were collected from subjects scalp using a commercial wireless EEG device in two experimental conditions - when subjects did not wear space suit (control condition) and when subjects wore space suit. Brain state changes were estimated and compared with the direct responses for different tasks and different conditions. We found that the spacesuit experiment introduced a greater mental workload where subject's stress levels were higher than control experiment. PMID:23366693

  18. Influence of peripheral blood hemoglobin concentration on the result of radiotherapy for nasopharyngeal carcinoma

    International Nuclear Information System (INIS)

    Objective: To determine the influence of peripheral blood hemoglobin concentration on the radiotherapy result of nasopharyngeal carcinoma (NPC). Methods: From January 1989 to December 1998, 304 patients with pathologically confirmed NPC received radical radiation. There were 209 males and 95 females. The ages ranged from 16 to 77 years with a median of 42. All patients were irradiated by 60Co or 6 MV external beam with a total dose of 64 - 76 Gy for the primary tumor and 46 - 77 Gy for the cervical lymph nodes. The peripheral blood hemoglobin concentration for all patients was measured before, during and after radiotherapy. These patients were divided into three groups according to the peripheral blood hemoglobin concentration before radiotherapy: anemia ( 160 g/L), and into two groups according to the change in the peripheral blood hemoglobin concentration during radiotherapy as increased and decreased groups. Results: All patients were followed with a follow-up rate of 90.5%. The peripheral blood hemoglobin concentration had a significant effect on the survival of NPC patients. Its decrease or increase during radiotherapy affected the survival and local control rates of NPC patients. Conclusions: The change of peripheral hemoglobin concentration affecting the oxygen content in the blood, can influence the local control and survival rates of NPC patients. Increase results in higher survival

  19. The Swedish National Care Programme for Anal Carcinoma. Implementation and overall results

    International Nuclear Information System (INIS)

    The Swedish National Care Programme for Anal Carcinoma (SNCPAC) was instituted in order to create a uniform handling policy for anal cancer and thus to accrue a population-based material allowing unbiased analyses. This study evaluates the degree of implementation of the SNCPAC guidelines, and presents overall treatment results in a total of 356 patients with epidermoid cancer of the anus and the perianal region diagnosed in Sweden between 1985 and 1989. Primary treatment according to the guidelines was irradiation up to 40 Gy. Bleomycin was administered intramuscularly before the first 18 fractions. After a 3-week pause, radiotherapy was to be continued up to a dose of 60-64 Gy, if at least an almost complete response was achieved. Otherwise, the patient was recommended surgery within a week. The guidelines were applied in 90% of cases where such treatment was possible. The 5-year tumour-specific survival rate was 72%. The survival rate was more favourable in perianal tumours (90%) than in anal canal tumours (68%, p<0.01). The 5-year probability of having a preserved anus was 64% (anal canal/perianal 58%/91%, p<0.001). Bleomycin did not appear to have any effect on treatment results. The care programme has had a rapid and almost complete nation-wide penetration, and has created the desired uniformity allowing proper analyses. The treatment results also appear comparable with specialised referral centres. (orig.)

  20. Dissolved air flotation for treating wastewater of the nuclear industry. Preliminary results

    International Nuclear Information System (INIS)

    Preliminary testing of dissolved air flotation (DAF) for wastewater treatment is presented. A combined coagulation-flocculation/DAF column system is used to remove oil and 60Co from nuclear industry wastewater. In this work, operational conditions and coagulant/flocculant concentrations are optimized by varying pH. Determinations of air-solids ratio (G/S), retention time (θ), pressure (P), volume of depressurized air-water mixture (V), turbidity and 60Co concentrations are reported. The effect of the treatment on the efficiency of separation of oily residues is also discussed. The results establish that the coagulant/flocculant system, formed by a modified polyamine (25 mgL-1) and a slightly cationic polyacrylamide (1.5 mgL-1), under specific operational conditions (pH = 7, mixing intensity Im1 = 300 s-1 and Im2 = 30 s-1), allowed the destabilization of colloidal matter, resulting in resistant flocs. It was concluded that by using G/S = 0.3, θ = 15 min, P = 620 kPa and V = 0.0012 m3, the greatest percentage removals of oil, turbidity, total cobalt and 60Co were obtained. These preliminary results then show that dissolved air flotation represents a good alternative for treatment of nuclear industry wastewater contaminated with radionuclides. (author)

  1. Consumption of vegetables and fruits and risk of ovarian carcinoma: Results from the Netherlands Cohort Study on Diet and Cancer

    NARCIS (Netherlands)

    Mommers, M.; Schouten, L.J.; Goldbohm, R.A.; Brandt, P.A. van den

    2005-01-01

    BACKGROUND. To the authors' knowledge, only a few prospective studies to date have investigated the correlation between vegetable and fruit consumption and the risk of ovarian carcinoma and their results have been inconclusive. METHODS. Vegetable and fruit intake was assessed in relation to ovarian

  2. Nuclear Reactor Component Code CUPID-I: Numerical Scheme and Preliminary Assessment Results

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Hyoung Kyu; Jeong, Jae Jun; Park, Ik Kyu; Kim, Jong Tae; Yoon, Han Young

    2007-12-15

    A component scale thermal hydraulic analysis code, CUPID (Component Unstructured Program for Interfacial Dynamics), is being developed for the analysis of components of a nuclear reactor, such as reactor vessel, steam generator, containment, etc. It adopted three-dimensional, transient, two phase and three-field model. In order to develop the numerical schemes for the three-field model, various numerical schemes have been examined including the SMAC, semi-implicit ICE, SIMPLE, Row Scheme and so on. Among them, the ICE scheme for the three-field model was presented in the present report. The CUPID code is utilizing unstructured mesh for the simulation of complicated geometries of the nuclear reactor components. The conventional ICE scheme that was applied to RELAP5 and COBRA-TF, therefore, were modified for the application to the unstructured mesh. Preliminary calculations for the unstructured semi-implicit ICE scheme have been conducted for a verification of the numerical method from a qualitative point of view. The preliminary calculation results showed that the present numerical scheme is robust and efficient for the prediction of phase changes and flow transitions due to a boiling and a flashing. These calculation results also showed the strong coupling between the pressure and void fraction changes. Thus, it is believed that the semi-implicit ICE scheme can be utilized for transient two-phase flows in a component of a nuclear reactor.

  3. Qualitative Measurement of Landscape Structure in an Urbanizing Region: A New Method and Preliminary Results

    Science.gov (United States)

    Bunn, J. T.

    2006-12-01

    Landscape pattern analysis typically involves the mathematical derivation of quantitative metrics from classified rasterized aerial images and/or maps. Recent work by architect Christopher Alexander, however, suggests a new holistic approach to the measurement of landscape structure, based on properties of the relationships between coherent wholes. Measurement of these properties and relationships relies upon qualitative judgment and aesthetic perception, but can be quantified using ordinal scaling and tests of intersubject agreement. I demonstrate how these qualitative pattern measures can be assessed through the use of aerial orthophotographs, and describe preliminary results relating them to an indicator of biodiversity in the urbanizing Pacific Northwest (USA) landscape. I conducted a double-blind survey in which subjects used Alexander's properties to compare aerial photographs of 1 km2 landscapes along an urban to rural gradient in the vicinity of Seattle, Washington. The photographs were of locations with measured avian biodiversity, and represent a range of land-cover types and development patterns. Subjects compared 23 pairs of images, using aesthetic judgement to choose the one in each pair that they felt expresses Alexander's properties to a greater degree. Preliminary results indicate that intersubjective agreement is significantly better than chance for most image pairs (p <= 0.05), and that for most subjects the photographs judged higher in Alexander's properties correspond to the locations with higher bird species richness, at a frequency significantly greater than would be expected by chance (p <= 0.05).

  4. Preliminary results of combined ESR/U-series dating of fossil teeth from Longgupo cave, China

    International Nuclear Information System (INIS)

    Longgupo Cave site, located in Wushan County, Chongqing, China has attracted continuous attention since its discovery of hominid remains in association with late Pliocene-early Pleistocene fauna and numerous lithic artefacts. In 2003-2006, new excavation was carried out on this site, allowing the description of a detailed stratigraphy of the highly complex cave in-fillings and the sampling of teeth for combined ESR/U-series analyses. Here we report preliminary dating results of seven herbivorous fossil teeth from different archaeological layers of the lowest geological unit (C III). Uranium-series analyses indicate that no obvious uranium leaching has occurred and all the teeth (except one) underwent a very recent uranium uptake history. The obtained US-ESR results show that the age of six teeth are basically consistent, between similar to 1.4 and 1.8 Ma. At the same time, we observed an inverse correlation of two samples with the stratigraphic sequence. This could be caused by the distinct uranium uptake history of one sample, high uranium content in the enamel for another or bad estimation of external dose rate. Due to the complexity of the stratigraphic sequence, supplementary in situ gamma dose rate measurement should be performed for all the samples during the following excavations in order to confirm this preliminary ESR/U-series chronology. (authors)

  5. Treatment results and prognostic factors in 101 men treated for squamous carcinoma of the penis

    International Nuclear Information System (INIS)

    Purpose: This retrospective study was performed to assess the treatment outcome and prognostic factors in 101 men with invasive squamous carcinoma of the penis treated at the Royal Marsden Hospital between 1960-1990. Methods and Materials: The tumor was confined to the glans penis (T1) in 79 patients, 82 were node negative (N0), and two patients had distant metastases at presentation. The histology was Grade 1 (G1) in 36, Grade 2 (G2) in 18, Grade 3 (G3) in 28, and unknown in 19 patients. Node-positive disease was commoner in patients with G3 (p = 0.02) or T2/3/4 tumors (p = 0.007). Treatment for the primary tumor was external beam radiotherapy (EBRT) in 59, interstitial brachytherapy in 13, and partial or total penectomy in 29 patients. The median dose, dose/fraction, and treatment time for EBRT was 60 Gy, 2 Gy/fraction, and 46 days, respectively. Eighty patients received no inguinal node treatment, 13 had EBRT (4 with chemotherapy), and 8 underwent groin dissection at presentation. Results: During a median follow-up of 5.2 years (2 months-22 years), 56 patients died (penile cancer 31, inter-current illness 23 and unknown cause 2), giving 10 year overall and cause-specific survival (CSS) of 39 and 57%, respectively. Adverse prognostic factors for CSS on univariate analysis were G3, ulcerative/fungating or T2/3/4 tumors, node positive, Jackson's Stage 2/3/4, and surgical treatment for the primary. All but the last two were significant independent prognostic factors for CSS on multivariate analysis. Penile or perineal recurrence or residual disease after initial treatment was seen in 36 out of 98 evaluable patients, giving a 10-year local failure rate (LFR) of 45%. Local failure after initial treatment was successfully salvaged in the majority (26 out of 36) of patients with further surgery or radiotherapy, and local control was achieved ultimately in 74 out of 77 T1, 7 out of 12 T2; 3 out of 3 T3, and 3 out of 5 T4 tumors. In the 44 evaluable patients with T1

  6. Preliminary results from the investigation of thermal effects in electrokinetics soil remediation

    International Nuclear Information System (INIS)

    Electrokinetics is an emerging soil remediation technology. Contaminants are extracted from the soil as a result of a complex set of phenomena that occur when an electric gradient is imposed across a soil-water system. The primary phenomena include electroosmosis, electromigration, and electrophoresis. Secondary phenomena, such as changes in solubility or speciation of various chemical components, may occur as a result of electrically induced changes in the chemical environment of the system. Numerous factors, such as temperature, may affect each of these phenomena and, consequently, the overall process efficiency. We have begun an investigation of thermal effects in the extraction of potassium dichromate from kaolinite soils under conditions of constant saturation and dewatering. Preliminary results suggest that increasing the soil temperature from 21 to 55 degrees C may decrease the processing time under saturated conditions. However, increasing the soil temperature under dewatering, conditions causes soil cracking, which reduces the overall process efficiency

  7. Indications and results of postoperative radiotherapy in case of vulvar carcinoma

    International Nuclear Information System (INIS)

    Between 1968 and 1979, 132 patients with squamous cell carcinomas of the vulva were submitted to a more or less radical operation. Then they were irradiated at the Radiologic Center of the GHS Essen. All patients received irradiations of the vulvar region with high energy electrons combined with photons (n=78) as well as photons or electrons alone (n=15 and 39, respectively). The dose was generally 40 to 60 Gy. 81 patients (61.4%) were additionally irradiated in the inguinal region. The overall three-year and five-year survival rate is 48.5 and 34.1%, respectively. The median survival time is 31.5 months. Contrary to expectation there were no significantly different recurrence rates after radical vulvectomy and large excision combined with postoperative irradiation. This is attributed to the favorable effect of radiotherapy. A graduated conception has been elaborated based on the results of our retrospective analysis and the communications of literature. Radical vulvectomy and inguinal lymphadenectomy is the therapy of choice. Radiotherapy in the vulvar region should be applied if radical surgery seems problematic or is not possible. Irradiation of lymph node regions is indicated if they are involved or if a resection is not possible. (orig.)

  8. Indications and results of postoperative radiotherapy in case of vulvar carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Alberti, W.; Katsilieris, I.; Schulz, U.; Callies, R.

    1986-08-01

    Between 1968 and 1979, 132 patients with squamous cell carcinomas of the vulva were submitted to a more or less radical operation. Then they were irradiated at the Radiologic Center of the GHS Essen. All patients received irradiations of the vulvar region with high energy electrons combined with photons (n=78) as well as photons or electrons alone (n=15 and 39, respectively). The dose was generally 40 to 60 Gy. 81 patients (61.4%) were additionally irradiated in the inguinal region. The overall three-year and five-year survival rate is 48.5 and 34.1%, respectively. The median survival time is 31.5 months. Contrary to expectation there were no significantly different recurrence rates after radical vulvectomy and large excision combined with postoperative irradiation. This is attributed to the favorable effect of radiotherapy. A graduated conception has been elaborated based on the results of our retrospective analysis and the communications of literature. Radical vulvectomy and inguinal lymphadenectomy is the therapy of choice. Radiotherapy in the vulvar region should be applied if radical surgery seems problematic or is not possible. Irradiation of lymph node regions is indicated if they are involved or if a resection is not possible.

  9. A preliminary study on transcatheter arterial chemoembolization with polyvinyl alcohol particles in patients with large hepatocellular carcinoma

    International Nuclear Information System (INIS)

    Objective: To evaluate the efficacy and safety of transcatheter arterial chemoembolization (TACE) with 355-500 μm polyvinyl alcohol (PVA) particles for treatment of larger hepatocellular carcinoma (HCC). Methods: Seventy-three patients with larger HCC had been undergone TACE. Median tumor size was 12.3 (range 8.4-20.4) cm with Child-Pugh class A in all patients. The chemotherapy agents, Lipiodol and PVA were injected into tumor artery for each patient, with dose of PVA 100 mg for 71 patients. 200 mg and 50 mg for each of other cases, respectively. The changes and responses of liver function and tumor size were noted. Results: The tumor size decreased with an average of 3 cm (P<0.01). The iatrogenic insult of liver function was increased (P<0.001). Conclusions: TACE with use of PVA for larger HCC is an effective and feasible treatment modality, but preventive therapy for liver function failure has to be taken after the TACE. (authors)

  10. A color spectrographic phonocardiography (CSP applied to the detection and characterization of heart murmurs: preliminary results

    Directory of Open Access Journals (Sweden)

    Hassani Kamran

    2011-05-01

    Full Text Available Abstract Background Although cardiac auscultation remains important to detect abnormal sounds and murmurs indicative of cardiac pathology, the application of electronic methods remains seldom used in everyday clinical practice. In this report we provide preliminary data showing how the phonocardiogram can be analyzed using color spectrographic techniques and discuss how such information may be of future value for noninvasive cardiac monitoring. Methods We digitally recorded the phonocardiogram using a high-speed USB interface and the program Gold Wave http://www.goldwave.com in 55 infants and adults with cardiac structural disease as well as from normal individuals and individuals with innocent murmurs. Color spectrographic analysis of the signal was performed using Spectrogram (Version 16 as a well as custom MATLAB code. Results Our preliminary data is presented as a series of seven cases. Conclusions We expect the application of spectrographic techniques to phonocardiography to grow substantially as ongoing research demonstrates its utility in various clinical settings. Our evaluation of a simple, low-cost phonocardiographic recording and analysis system to assist in determining the characteristic features of heart murmurs shows promise in helping distinguish innocent systolic murmurs from pathological murmurs in children and is expected to useful in other clinical settings as well.

  11. Radioinduced modifications of the skin relief: preliminary results in the pig

    International Nuclear Information System (INIS)

    The evolution of the cutaneous relief depends on physiological and physical parameters such as sex, aging, hydratation and radiations. Composed of plateaus crossed by valleys, the skin surface topography can be studied by a 3D topographic and a 2D profilometric analysis of the distribution of the relief parameters. This preliminary study of the irradiated skin topography showed a relative decrease of the vertical amplitude parameters (-15%) of the skin relief in three pigs irradiated with single doses of 90Sr-90Y β rays (32,64 and 96 Gy under 7 mg/cm2; skin source distance: 2.6 cm) and one pig irradiated with a single dose of 192Ir γ rays (160 Gy skin surface dose; skin source distance: 1.7 cm), 24 h after irradiation whatever the dose. This preliminary result will be developed in a larger study group of pigs and a longer time period, to define the threshold dose of irradiation that induces modifications of the skin topography, before being validated in humans. (authors). 26 refs., 3 figs., 2 tabs

  12. Preliminary assessment of the Long Island National Wildlife Refuge Complex Environmental contaminants background survey: Second year results

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report represents the preliminary results of the second year of the multiyear study, The Long Island National Wildlife Refuge Complex (Complex) Environmental...

  13. Properties of ABNT 41xx and 86xx cast steel modified with niobium; evaluation methodology and experimental preliminary results

    International Nuclear Information System (INIS)

    The experimental methodology to evaluate the mechanical properties of ABNT 41xx and 86xx steels modified with NB in the as cast and heat treated conditions and the first preliminary results obtained in a laboratory scale, are presented. (Author)

  14. Preliminary assessment of the Long Island National Wildlife Refuge Complex environmental contaminants background study: Fifth year results

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report represents the preliminary results of the fifth year of the multiyear study entitled, "The Long Island National Wildlife Refuge Complex (Complex)...

  15. Hybrid Spectral Micro-CT: System Design, Implementation, and Preliminary Results

    CERN Document Server

    Bennett, James R; Xu, Qiong; Yu, Hengyong; Walsh, Michael; Butler, Anthony; Butler, Phillip; Cao, Guohua; Mohs, Aaron; Wang, Ge

    2014-01-01

    Spectral CT has proven an important development in biomedical imaging, and there have been several publications in the past years demonstrating its merits in pre-clinical and clinical applications. In 2012, Xu et al. reported that near-term implementation of spectral micro-CT could be enhanced by a hybrid architecture: a narrow-beam spectral "interior" imaging chain integrated with a traditional wide-beam "global" imaging chain. This hybrid integration coupled with compressive sensing (CS)-based interior tomography demonstrated promising results for improved contrast resolution, and decreased system cost and radiation dose. The motivation for the current study is implementation and evaluation of the hybrid architecture with a first-of-its-kind hybrid spectral micro-CT system. Preliminary results confirm improvements in both contrast and spatial resolution. This technology is shown to merit further investigation and potential application in future spectral CT scanner design.

  16. Modelling lung cancer due to radon and smoking in WISMUT miners: Preliminary results

    International Nuclear Information System (INIS)

    A mechanistic two-stage carcinogenesis model has been applied to model lung-cancer mortality in the largest uranium-miner cohort available. Models with and without smoking action both fit the data well. As smoking information is largely missing from the cohort data, a method has been devised to project this information from a case-control study onto the cohort. Model calculations using 256 projections show that the method works well. Preliminary results show that if an explicit smoking action is absent in the model, this is compensated by the values of the baseline parameters. This indicates that in earlier studies performed without smoking information, the results obtained for the radiation parameters are still valid. More importantly, the inclusion of smoking-related parameters shows that these mainly influence the later stages of lung-cancer development. (authors)

  17. MAX-DOAS measurements of tropospheric NO2 over San Salvador: preliminary results

    Science.gov (United States)

    Alberti, Carlos; Wagner, Thomas

    2015-04-01

    We present the first Multi-AXis-Differential Optical Absorption Spectroscopy (MAX-DOAS) measurements at San Salvador. MAX-DOAS observes spectra of scattered sun light taken at different elevation angles. From the spectra the so called slant column density (SCD, the integrated trace gas concentration along the atmospheric light path) is derived. We quantify the dSCD of NO2 at different measurement conditions. From the measured NO2 SCDs we calculate the tropospheric vertical column density using the so called geometric approximation. The preliminary results of this MAX DOAS observations and the diurnal variation of the retrieved trace gas dSCDs will be presented. We also use the MAX-DOAS results for the validation of satellite observations.

  18. Comparison of stroke infarction between CT perfusion and diffusion weighted imaging: preliminary results

    Science.gov (United States)

    Abd. Rahni, Ashrani Aizzuddin; Arka, Israna Hossain; Chellappan, Kalaivani; Mukari, Shahizon Azura; Law, Zhe Kang; Sahathevan, Ramesh

    2016-03-01

    In this paper we present preliminary results of comparison of automatic segmentations of the infarct core, between that obtained from CT perfusion (based on time to peak parameter) and diffusion weighted imaging (DWI). For each patient, the two imaging volumes were automatically co-registered to a common frame of reference based on an acquired CT angiography image. The accuracy of image registration is measured by the overlap of the segmented brain from both images (CT perfusion and DWI), measured within their common field of view. Due to the limitations of the study, DWI was acquired as a follow up scan up to a week after initial CT based imaging. However, we found significant overlap of the segmented brain (Jaccard indices of approximately 0.8) and the percentage of infarcted brain tissue from the two modalities were still fairly highly correlated (correlation coefficient of approximately 0.9). The results are promising with more data needed in future for clinical inference.

  19. RR Lyrae search and stellar populations study in Canis Major: Preliminary Results

    CERN Document Server

    Mateu, C E; Zinn, R; Miller, L; Mateu, Cecilia E.; Zinn, Robert; Miller, Lissa

    2005-01-01

    We present preliminary results of a RR Lyrae star search and stellar populations study performed in the Canis Major overdensity, spanning an area of 8.35sq deg. The observations were made in R and V bands, with the QUEST camera installed in the 1m Jurgen Stock Telescope, at the Venezuela National Observatory. The resulting Hess diagram shows a possible, but weak, red giant branch and no obvious horizontal branch, red clump or main sequence turnoff. After a multi--epoch photometric search, 6 RR Lyrae stars were confirmed with further observations obtained at the 1.0 and 1.3m telescopes of the SMARTS consortium at CTIO. Of these confirmed RR Lyrae stars, 5 have heliocentric distances between 5 and 7 kpc. Confirmation of their physsical association with the Canis Major system awaits for a study of their radial velocities.

  20. PDM performance Test Results and Preliminary Analysis: Incompressible and Compressible Fluids

    Energy Technology Data Exchange (ETDEWEB)

    Dreesen, D.S.; Gruenhagan, E.; Cohen, J.C.; Moran, D.W.

    1999-02-01

    Three, small diameter, Moineau, positive displacement (drilling) motors (PDMs) were dynamometer tested using water, air-water mist, air-water foam, and aerated water. The motors included (1) a 1.5-inch OD, single-lobe mud motor; (2) a 1.69-inch OD, 5:6 multi-lobe mud motor; and (3) a 1.75-inch OD, 5:6 multi-lobe air motor. This paper describes the test apparatus, procedures, data analysis, and results. Incompressible and compressible fluid performance are compared; linear performance, predicted by a positive displacement motor model, is identified where it occurs. Preliminary results and conclusions are (1) the performance of all three motors is accurately modeled using a two-variable, linear model for incompressible fluid and (2) the model was not successfully adapted to model compressible fluid performance.

  1. MAX-DOAS observations of trace gases over Mainz: preliminary results

    Science.gov (United States)

    Alberti, Carlos; Gu, Myojeong; Remmers, Julia; Wagner, Thomas

    2014-05-01

    In this work we report on levels of trace gases in ambient atmosphere in Mainz, Germany. We measured the differential Slant Column Density (dSCD) of NO2, HCHO and O4 in the ultraviolet region of the electromagnetic spectrum using a Mini-MAX-DOAS instrument. The MAX-DOAS observations were taken at Max Planck Institute for Chemistry in Mainz, from January to March 2014, at different elevation angles. The main aim of the study is to compare the results of the Mini-MAX-DOAS instrument with those from a 'scientific' MAX-DOAS instrument operated simultaneously at the same location. We quantify systematic differences and random and errors of both data sets for different measurement conditions. The preliminary results of this MAX DOAS observations and the diurnal variation of the retrieved trace gas DSCDs will be discussed in this work.

  2. Preliminary results of measurement of natural environmental radiation levels and doses to population in China

    International Nuclear Information System (INIS)

    In this paper the preliminary results of measurement of natural environmental radiation levels in China with RSS-111 high pressure ionization chamber and estimated doses to population are reported. A total of 2,723 indoor locales throughout China were measured. The results showed that the average absorbed dose rates in air due to gamma radiation for indoors and outdoors were 11.0 x 10-8 Gy.h-1 and 7.4 x 10-8 Gy.h-1, respectively, and those due to cosmic rays were 3.2 x 10-8 Gy.h-1 and 3.7 x 10-8 Gy.h-1, respectively. The annual average effective dose equivalent to population was 919 μSv, including 630 μSv from natural gamma radiation and 289 μSv from cosmic rays

  3. Measurement of pressure ridges in SAR images of sea ice - Preliminary results on scattering theory

    Science.gov (United States)

    Vesecky, J. F.; Smith, M. P.; Daida, J. M.; Samadani, R.; Camiso, J. C.

    1992-01-01

    Sea ice ridges and keels (hummocks and bummocks) are important in sea ice research for both scientific and practical reasons. A long-term objective is to make quantitative measurements of sea ice ridges using synthetic aperture radar (SAR) images. The preliminary results of a scattering model for sea ice ridge are reported. The approach is through the ridge height variance spectrum Psi(K), where K is the spatial wavenumber, and the two-scale scattering model. The height spectrum model is constructed to mimic height statistics observed with an airborne optical laser. The spectrum model is used to drive a two-scale scattering model. Model results for ridges observed at C- and X-band yield normalized radar cross sections that are 10 to 15 dB larger than the observed cross sections of multiyear ice over the range of angles of incidence from 10 to 70 deg.

  4. Development of methods to measure hemoglobin adducts by gel electrophoresis - Preliminary results

    International Nuclear Information System (INIS)

    Chemical adducts formed on blood hemoglobin may be a useful biomarker for assessing human exposures to these compounds. This paper reports preliminary results in the development of methods to measure such adducts that may be generally applicable for a wide variety of chemicals. Male F344/N rats were intraperitoneally injected with 14C-BaP dissolved in corn oil. Twenty-four hours later, the rats were sacrificed. Blood samples were collected and globin was isolated. Globin protein was then cleaved into peptide fragments using cyanogen bromide and the fragments separated using 2-dimensional gel electrophoresis. The results showed that the adducted 14C-globin fragments migrated to different areas of the gel than did unadducted fragments. Further research is being conducted to develop methods that will allow quantitation of separated adducted globin fragments from human blood samples without the use of a radiolabel. (author)

  5. Modelled and Observed Diurnal SST Signals: "SSTDV:R.EX.-IM.A.M." Project Preliminary Results

    DEFF Research Database (Denmark)

    Karagali, Ioanna; Høyer, Jacob; LeBorgne, Pierre;

    2013-01-01

    This study presents some of the preliminary results from the ESA Support To Science Element (STSE) funded project on the Diurnal Variability of the Sea Surface Temperature, regarding its Regional Extend and Implications in Atmospheric Modelling (SSTDV:R.EX.–IM.A.M.). During this phase of the...... project, the focus is on the regional extend of diurnal variability. Particularly, extensive sensitivity tests regarding the definition of SSTfound fields show that using only quality 5 SEVIRI data results in warmer foundation fields SSTfound while there is an added ∼0.2 K variability when using multi......-day composites. Diurnal warming signals exceeding 1 K are identified in the European Seas but also in the mid-latitudes of the North and South Atlantic as well as in areas with strong currents. In the attempt to connect temperature measurements from satellites and in situ instruments, the 1-dimensional General...

  6. Sugars as double-signal high dose dosimeters of ionizing radiation. Preliminary results

    International Nuclear Information System (INIS)

    Preliminary results of investigation of some sugars (maltose, saccharose, commercial sugar) as sensor materials for a high dose dosimetry of ionizing radiation are presented. An advantage of using sugars consists in fact that ionizing radiation creates in them two kind of signals: colour centers (spectrophotometric read-out) and paramagnetic centers (read-out by EPR method). This allows to chose more convenient - in particular conditions a method of analysis and more exactly to estimate uncertainties connected with analytical procedures. The results indicate saccharose as better than others dosimetric material with a threshold at ∼ 100 Gy for the EPR method and ∼ 5 Gy for the optical one. The investigation reveals a high discrepancy of physicochemical parameters and generally a low quality of Polish grocery sugar. (author)

  7. Life span studies on mice exposed to heavy charged particles or photons: preliminary results

    International Nuclear Information System (INIS)

    This chapter summarizes the results currently available where dose-dependent mortality is compared among the single cohort that received fractionated doses of carbon ions and the first replicate that received single doses. At this time, 17% mortality has occurred in both groups and had enhanced life shortening been produced by fractionation of the carbon ion dose, somewhat higher mortality might be expected. Cautious interpretation of these preliminary results is necessary, but the mortality data available at this time provides no evidence for enhancement by dose fractionation with carbon ions. In sum, at this time, it appears the Q factor used for fission spectrum neutrons could be conservative if it were used for assessment of risk following exposure to 400 MeV carbon ions

  8. Parotid carcinoma

    DEFF Research Database (Denmark)

    Sørensen, Kristine Bjørndal; Godballe, Christian; de Stricker, Karin;

    2006-01-01

    OBJECTIVES: Our aim is to investigate the expression of kit protein (KIT) and epidermal growth factor receptor (EGFR) in parotid carcinomas in order to correlate the expression to histology and prognosis. Further we want to perform mutation analysis of KIT-positive adenoid cystic carcinomas....... PATIENTS AND METHODS: Formalin-fixed paraffin-embedded sections from 73 patients with parotid gland carcinomas were used for the study. The sections were stained with both KIT and EGFR polyclonal antibodies. Twelve KIT-positive adenoid cystic carcinomas were examined for c-kit mutation in codon 816....... RESULTS: Of all carcinomas 25% were KIT-positive and 79% were EGFR-positive. Ninety-two percentage of the adenoid cystic carcinomas were KIT-positive. None of the adenoid cystic carcinomas had mutations in codon 816 of the c-kit gene. CONCLUSION: Neither KIT- nor EGFR-expression seem to harbour...

  9. Differentiating laryngeal carcinomas from precursor lesions by diffusion-weighted magnetic resonance imaging at 3.0 T: a preliminary study.

    Directory of Open Access Journals (Sweden)

    De-Sheng Shang

    Full Text Available BACKGROUND: Diffusion-weighted magnetic resonance imaging (DWI has been introduced in head and neck cancers. Due to limitations in the performance of laryngeal DWI, including the complex anatomical structure of the larynx leading to susceptibility effects, the value of DWI in differentiating benign from malignant laryngeal lesions has largely been ignored. We assessed whether a threshold for the apparent diffusion coefficient (ADC was useful in differentiating preoperative laryngeal carcinomas from precursor lesions by turbo spin-echo (TSE DWI and 3.0-T magnetic resonance. METHODS: We evaluated DWI and the ADC value in 33 pathologically proven laryngeal carcinomas and 17 precancerous lesions. RESULTS: The sensitivity, specificity, and accuracy were 81.8%, 64.7%, 76.0% by laryngostroboscopy, respectively. The sensitivity, specificity, and accuracy of conventional magnetic resonance imaging were 90.9%, 76.5%, 86.0%, respectively. Qualitative DWI analysis produced sensitivity, specificity, and accuracy values of 100.0, 88.2, and 96.0%, respectively. The ADC values were lower for patients with laryngeal carcinoma (mean 1.195±0.32×10(-3 mm(2/s versus those with laryngeal precancerous lesions (mean 1.780±0.32×10(-3 mm(2/s; P<0.001. ROC analysis showed that the area under the curve was 0.956 and the optimum threshold for the ADC was 1.455×10(-3 mm(2/s, resulting in a sensitivity of 94.1%, a specificity of 90.9%, and an accuracy of 92.9%. CONCLUSIONS: Despite some limitations, including the small number of laryngeal carcinomas included, DWI may detect changes in tumor size and shape before they are visible by laryngostroboscopy. The ADC values were lower for patients with laryngeal carcinoma than for those with laryngeal precancerous lesions. The proposed cutoff for the ADC may help distinguish laryngeal carcinomas from laryngeal precancerous lesions.

  10. Towards seasonal hydrological forecasting in mountain catchments: preliminary results from the APRIL project

    Science.gov (United States)

    Pistocchi, Alberto; Mazzoli, Paolo; Bagli, Stefano; Notarnicola, Claudia; Pasolli, Luca

    2013-04-01

    The APRIL project aims at addressing the long term quantitative prediction of monthly discharge from mountain catchments and setting up a system which can then be used operationally. More specifically, its objectives are: - To investigate the potential of EO products (snow cover extent, vegetation and soil moisture statust) and weather/climatic variables for the prediction of water streamflow from mountain catchments - To develop a robust methodology for the long term quantitative forecast of montly discharge from EO and weather/climatic data - To build a fully operational system for seasonal hydrological forecasting. This contribution illustrates the general concept of the project as well as some preliminary results. Water discharge in mountain catchments is physically related to antecedent snow cover and climatology (precipitation, temperature). Other factors may play a role, such as vegetation/soil status and topography. Historical discharge measurements and earth observation (EO) data are a valuable source for inferring the quantitative relationship between the discharge and its predictors using appropriate techniques. The prediction is based on the Support Vector Regression (SVR)technique, a state of the art machine learning regression method with good intrinsic generalization ability and robustness. In the contribution we present and discuss results of a preliminary analysis on water discharge prediction ( with lead time of 1 to 3 months) in South Tyrol, Italy. Despite the use of a limited set of predictors (among which mainly snow cover area), the results are encouraging. The analysis is in the process of being extended at different spatial scales, which will give the possibility to investigate different aspects of the problem and develop different prediction systems; by updating on the current developments, the contribution discusses also perspectives and current limitations towards the set up of a fully operational seasonal hydrological forecasting system

  11. Treatment Result in Advanced T3 and T4 Glottic Carcinoma; YUMC Experience

    International Nuclear Information System (INIS)

    Between January 1980 and September 1988, 68 patients with advanced T3 and T4 glottic carcinoma were treated with RT and surgery/RT in the Department of Radiation Oncology, Yonsei Cancer Center and ENT, Yonsei University College of Medicine. The mean age was 60 years old (range 33 to 79 year old). The 34 patients were treated with irradiation alone, and the remaining 34 patients with surgery and irradiation. Initial nodal presentation was 37% (25/68); 31% (11/34) in RT alone group and 41% (14/34) in combined treatment group. The minimum follow-up was 2 years. The local control rate after treatment was 47% in RT alone group and 65% in combined treatment group; 57% for node negative and 27% for node positive patients treated with RT alone; 65% for node negative and 64% for node positive patients treated with combined treatment. The treatment failure was observed in 30 patients; 14 patients for primary local failure, 6 patients for regional nodal failure, 6 patients for local and regional failure, 26 patients for primary failure and/or distant metastasis, and 2 patient for regional failure and/or distant metastasis. The overall 5-year survival rate was 57%; 37% in RT alone group and 76% in combined treatment group; 55% for node negative and 20% for node positive patients treated with RT alone; 73% for node negative and 77% for node positive patients treated with combined treatment. In conclusion, the combined treatment groups in the treatment of advanced T3 and T4 glottic cancer showed the better results in local control rates and 5-year actuarial survival rates than RT alone group. We suggest that total laryngectomy and postoperative RT in the most patients of advanced glottic cancer were performed. However, in cases of node negative patients, RT alone is prefer as a treatment modality over combined surgery and RT since the treatment results were comparable and furthermore functional preservation could be achieved

  12. The midterm results of concurrent superselective arterial chemoradiotherapy for carcinoma of the external auditory canal and middle ear

    International Nuclear Information System (INIS)

    This study retrospectively reports the midterm results of concurrent superselective arterial chemoradiotherapy for carcinoma of the external auditory canal and middle ear. Fifteen patients (7 males and 8 females) who were treated for carcinoma of the external auditory canal and middle ear between March 2003 and July 2009 were enrolled in this study. The median follow-up period was 14 months (4-44 months). All patients were staged according to the Pittsburgh staging system by Moody as follows: T1 (n=1), T2 (n=1), T3 (n=1), T4 (n=12). Thirteen patients had squamous cell carcinoma, one had adenocarcinoma, and one had undifferentiated carcinoma. All catheterizations were performed via a transfemoral approach by the Seldinger method. After identifying the feeding arteries of the primary tumor, cisplatin (50 mg/body) was injected. Simultaneously a cisplatin antagonist, sodium thiosulfate, was administered intravenously. Four or five courses of arterial infusion were given weekly. The catheter was removed after each session. External beam irradiation was performed five times a week at 2 Gy per fraction. Total dose ranged from 40 to 60 Gy (median: 60 Gy). The toxicity was evaluated by Common Terminology Criteria for Adverse Events (CTC-AE) ver. 3.0. The 2-year overall survival (OS) rate was 73.4%, and progression free survival (PFS) rate was 53.3% for all patients. Concerning acute toxicity, one patient had Grade 3 dermatitis, and one had Grade 3 leucopenia. No catheter-related complications and no treatment-related deaths were observed. No severe late complications were observed, but one patient had a mild inflammation on the subcutaneous tissue. These results are comparable with those of other reports, suggesting that this method for carcinoma of the external auditory canal and middle ear is acceptable, but the OS rate and PFS rate need improvement. Further investigations are required with larger series to evaluate the long-term survival rate with this treatment. (author)

  13. Self-potential time series analysis in a seismic area of the Southern Apennines: preliminary results

    Directory of Open Access Journals (Sweden)

    V. Tramutoli

    1994-06-01

    Full Text Available The self-potential time series recorded during the period May 1991 - August 1992 by an automatic station, located in a seismic area of Southern Apennines, is analyzed. We deal with the spectral and the statistical features of the electrotellurie precursors: they can play a major role in the approach to seismic prediction. The time-dynamics of the experimental time series is investigated, the cyclic components and the time trends are removed. In particular we consider the influence of external noise, related to anthropic activities and meteoclimatic parameters, and pick out the anomalies from the residual series. Finally we show the preliminary results of the correlation between the anomalies in the time patterns of self-potential data and the earthquakes which occurred in the area.

  14. Raman scattering investigation of the water-bridge phenomenon: Some preliminary results

    Directory of Open Access Journals (Sweden)

    Francesco Aliotta

    2010-09-01

    Full Text Available A floating water-bridge is formed if a high-voltage direct current is applied between two beakers filled of chemically pure water. Raman spectra of the OH-stretching region have been obtained at ambient condition of temperature and pressure. These preliminary results seem to indicate that the hydrogen-bond structure is only slightly modified by the presence of the electric field applied to form the floating water-bridge in agreement with recent neutron scattering investigation. In fact, the polarized Raman spectrum of the pure water and of the water-bridge is almost superimposable. We are planning to carry out further spectroscopic analysis, at different thermodynamic conditions, for better understanding the role played by the hydrogen-bond in driving the formation of the floating water-bridge.

  15. Preliminary Results from VOC measurements in the Lower Fraser Valley in July/Aug 2012

    Science.gov (United States)

    Schiller, C. L.; Jones, K.; Vingarzan, R.; Leaitch, R.; Macdonald, A.; Osthoff, H. D.; Reid, K.

    2012-12-01

    In July/August 2012, a pilot study looking at the effect of ClNO2 production on the ozone concentrations in the lower Fraser valley near Abbotsford, BC was conducted. The lower Fraser valley in British Columbia Canada has some of the highest ozone concentrations and visibility issues in Canada. Abbotsford is located approximately 80 kms east of Vancouver, BC and approximately 30 kms from the ocean. The site was located in a largely agricultural area with fruit farms (raspberries and blueberries) and poultry barns predominating. During the study biogenic and anthropogenic VOCs were measured in situ using a GCMS/FID with hourly samples. Particle composition was measured using an ACSM and size distribution using an SMPS. Preliminary results from the study will be discussed.

  16. Polarimetry at 1.3 mm using MILLIPOL - methods and preliminary results for Orion

    International Nuclear Information System (INIS)

    This paper describes a polarimeter for use at wavelengths near 1 mm, designed to be self-contained and portable. Only minor modifications should be required to adapt this instrument for use on any of several millimeter and submillimeter telescopes. The polarimeter system and data-taking techniques are described, and a preliminary measurement is reported of the polarized dust emission from the Orion KL region at 1.3 mm using the NRAO 12 m telescope. The results are similar to previous polarization measurements of Orion at far-infrared and submillimeter wavelengths. The magnetic field direction implied by the polarization position angle is parallel to that found in the surrounding Orion region using optical and near- to midinfrared polarimetric techniques. 17 references

  17. Microwave frequency sweep interferometer for plasma density measurements in ECR ion sources: Design and preliminary results

    Science.gov (United States)

    Torrisi, Giuseppe; Mascali, David; Neri, Lorenzo; Leonardi, Ornella; Sorbello, Gino; Celona, Luigi; Castro, Giuseppe; Agnello, Riccardo; Caruso, Antonio; Passarello, Santi; Longhitano, Alberto; Isernia, Tommaso; Gammino, Santo

    2016-02-01

    The Electron Cyclotron Resonance Ion Sources (ECRISs) development is strictly related to the availability of new diagnostic tools, as the existing ones are not adequate to such compact machines and to their plasma characteristics. Microwave interferometry is a non-invasive method for plasma diagnostics and represents the best candidate for plasma density measurement in hostile environment. Interferometry in ECRISs is a challenging task mainly due to their compact size. The typical density of ECR plasmas is in the range 1011-1013 cm-3 and it needs a probing beam wavelength of the order of few centimetres, comparable to the chamber radius. The paper describes the design of a microwave interferometer developed at the LNS-INFN laboratories based on the so-called "frequency sweep" method to filter out the multipath contribution in the detected signals. The measurement technique and the preliminary results (calibration) obtained during the experimental tests will be presented.

  18. Microwave frequency sweep interferometer for plasma density measurements in ECR ion sources: Design and preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Torrisi, Giuseppe [INFN - Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy); University Mediterranea of Reggio Calabria, Reggio Calabria (Italy); Mascali, David; Neri, Lorenzo; Leonardi, Ornella; Celona, Luigi; Castro, Giuseppe; Agnello, Riccardo; Caruso, Antonio; Passarello, Santi; Longhitano, Alberto; Gammino, Santo [INFN - Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy); Sorbello, Gino [INFN - Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy); University of Catania, Catania, Italy and INFN-LNS, Catania (Italy); Isernia, Tommaso [University Mediterranea of Reggio Calabria, Reggio Calabria (Italy)

    2016-02-15

    The Electron Cyclotron Resonance Ion Sources (ECRISs) development is strictly related to the availability of new diagnostic tools, as the existing ones are not adequate to such compact machines and to their plasma characteristics. Microwave interferometry is a non-invasive method for plasma diagnostics and represents the best candidate for plasma density measurement in hostile environment. Interferometry in ECRISs is a challenging task mainly due to their compact size. The typical density of ECR plasmas is in the range 10{sup 11}–10{sup 13} cm{sup −3} and it needs a probing beam wavelength of the order of few centimetres, comparable to the chamber radius. The paper describes the design of a microwave interferometer developed at the LNS-INFN laboratories based on the so-called “frequency sweep” method to filter out the multipath contribution in the detected signals. The measurement technique and the preliminary results (calibration) obtained during the experimental tests will be presented.

  19. Preliminary Results on the Experimental Investigation of the Structure Functions of Bound Nucleons

    Energy Technology Data Exchange (ETDEWEB)

    Bodek, Arie [University of Rochester, Rochester, NY

    2015-09-01

    We present preliminary results on an experimental study of the nuclear modification of the longitudinal (σL) and transverse (σT) structure functions of nucleons bound in nuclear targets. The origin of these modifications (commonly referred as as the EMC effect) is not fully understood. Our measurements of R= σLT for nuclei (RA) and for deuterium (RD) indicate that nuclear modifications of the structure functions of bound nucleons are different for the longitudinal and transverse structure functions, and that contrary to expectation from several theoretical models, RA < RD.

  20. Preliminary results for the diffusion of water into fibre optic oil well sensors

    International Nuclear Information System (INIS)

    Preliminary results are presented on a measurement technique for determination of water penetration into fibre optic sensors under high pressure, high temperature conditions. Both fibre optic sensors and communication fibres were subjected to prolonged treatment in heavy water at temperatures up to 250 deg. C and pressures of 40 bar. Deuterium penetration is measured by a nuclear reaction technique based on a 3He micro-focussed ion beam, which permits two-dimensional mapping of the deuterium penetration into cleaved fibres. Water penetration can be detected whilst still confined to the cladding, well before any optical effects become apparent, permitting prediction of likely fibre lifetime under down-hole conditions after realistic experimental times

  1. Microwave frequency sweep interferometer for plasma density measurements in ECR ion sources: Design and preliminary results

    International Nuclear Information System (INIS)

    The Electron Cyclotron Resonance Ion Sources (ECRISs) development is strictly related to the availability of new diagnostic tools, as the existing ones are not adequate to such compact machines and to their plasma characteristics. Microwave interferometry is a non-invasive method for plasma diagnostics and represents the best candidate for plasma density measurement in hostile environment. Interferometry in ECRISs is a challenging task mainly due to their compact size. The typical density of ECR plasmas is in the range 1011–1013 cm−3 and it needs a probing beam wavelength of the order of few centimetres, comparable to the chamber radius. The paper describes the design of a microwave interferometer developed at the LNS-INFN laboratories based on the so-called “frequency sweep” method to filter out the multipath contribution in the detected signals. The measurement technique and the preliminary results (calibration) obtained during the experimental tests will be presented

  2. Radiotherapy of heterotopic bone formation in patients with paraplegia. Preliminary results

    International Nuclear Information System (INIS)

    In 20 patients with paralysis, 25 regions were irradiated with (mostly) 10 Gy in single fractions of 2 to 2.5 Gy using 8 MW photons. In 15 patients radiotherapy was performed as a primary treatment in the status of myositis; 7 patients were treated after (subtotal) resection of already manifest ossifications (2 patients were treated twice, primarily and postoperatively). In a minimum follow-up 12 weeks, none of the 20 irradiated patients showed any progression of the developing or already manifest ossification; thus mobilisation and rehabilitation could be carried out as desired. No side effects occurred. The preliminary results of the present study suggest that radiotherapy is an effective local treatment with minimal side effects for the prevention of heterotopic bone formation in patients with paraplegia. (orig.)

  3. Preliminary interpretation of the Libretto-2 experimental results in terms of tritium permeation barrier efficiency

    International Nuclear Information System (INIS)

    Within the framework of a European Community programme aiming at the development of a water-cooled lithium-lead (Pb17Li) blanket concept for a demonstration fusion reactor, important experimental works are devoted to the development of efficient tritium permeation barriers. Among them, in-pile tests (LIBRETTO experiments) with closed capsules containing stagnant Pb17Li are intended to assess under irradiation the efficiency of these barriers. In this paper, a method for interpreting LIBRETTO data is presented, which relies on the use of a 2-dimensional finite element simulation model exploiting the analogy between tritium migration and heat conduction. Preliminary results obtained with this model are also discussed, which seem to indicate that, under conditions comparable with the experiment, the permeation barrier tested in LIBRETTO-2 would reduce tritium permeation by a factor of about 80

  4. Preliminary interpretation of the LIBRETTO-2 experimental results in terms of tritium permeation barrier efficiency

    International Nuclear Information System (INIS)

    Within the framework of a European Community program aiming at the development of a water-cooled lithium-lead (Pb17Li) blanket concept for a demonstration fusion reactor [1,2], experimental works are devoted to the development of efficient tritium permeation barriers. These works include in-pile tests (LIBRETTO experiments) with closed steel capsules containing stagnant Pb17Li, intended to assess under irradiation the efficiency of these barriers. In this paper, a method for interpreting LIBRETTO data is presented, which relies on the use of a 2-dimensional finite element simulation model exploiting the analogy between tritium migration and heat conduction. Preliminary results obtained with this model are also discussed, which seem to indicate that, under conditions comparable with the experiment, the permeation barrier tested in LIBRETTO-2 would reduce tritium permeation by about two orders of magnitude. (orig.)

  5. Fuzzy-logic-based hybrid locomotion mode classification for an active pelvis orthosis: Preliminary results.

    Science.gov (United States)

    Yuan, Kebin; Parri, Andrea; Yan, Tingfang; Wang, Long; Munih, Marko; Vitiello, Nicola; Wang, Qining

    2015-08-01

    In this paper, we present a fuzzy-logic-based hybrid locomotion mode classification method for an active pelvis orthosis. Locomotion information measured by the onboard hip joint angle sensors and the pressure insoles is used to classify five locomotion modes, including two static modes (sitting, standing still), and three dynamic modes (level-ground walking, ascending stairs, and descending stairs). The proposed method classifies these two kinds of modes first by monitoring the variation of the relative hip joint angle between the two legs within a specific period. Static states are then classified by the time-based absolute hip joint angle. As for dynamic modes, a fuzzy-logic based method is proposed for the classification. Preliminary experimental results with three able-bodied subjects achieve an off-line classification accuracy higher than 99.49%. PMID:26737144

  6. Microwave frequency sweep interferometer for plasma density measurements in ECR ion sources: Design and preliminary results.

    Science.gov (United States)

    Torrisi, Giuseppe; Mascali, David; Neri, Lorenzo; Leonardi, Ornella; Sorbello, Gino; Celona, Luigi; Castro, Giuseppe; Agnello, Riccardo; Caruso, Antonio; Passarello, Santi; Longhitano, Alberto; Isernia, Tommaso; Gammino, Santo

    2016-02-01

    The Electron Cyclotron Resonance Ion Sources (ECRISs) development is strictly related to the availability of new diagnostic tools, as the existing ones are not adequate to such compact machines and to their plasma characteristics. Microwave interferometry is a non-invasive method for plasma diagnostics and represents the best candidate for plasma density measurement in hostile environment. Interferometry in ECRISs is a challenging task mainly due to their compact size. The typical density of ECR plasmas is in the range 10(11)-10(13) cm(-3) and it needs a probing beam wavelength of the order of few centimetres, comparable to the chamber radius. The paper describes the design of a microwave interferometer developed at the LNS-INFN laboratories based on the so-called "frequency sweep" method to filter out the multipath contribution in the detected signals. The measurement technique and the preliminary results (calibration) obtained during the experimental tests will be presented. PMID:26932081

  7. Equity in transportation: new approach in transport planning – preliminary results of case study in Cracow

    Directory of Open Access Journals (Sweden)

    Lidia ZAKOWSKA

    2014-09-01

    Full Text Available The goal of the paper is to present the concept of equity as a new approach in transport and land-use planning. This concept is consistent with the objectives of sustainable development and it is becoming more common in European and world literature. Understanding the idea of equity in the context of the transport system development is very important in creating sustainable cities and regions without discriminating any social groups and creating a cohesive society not exposed to social exclusion due to lack of access to primary and secondary activities. The paper presents some results of the preliminary analysis on transport equity in Cracow. The basic equity level which has been considered here concerns senior citizens, older people living in Cracow area, in terms of their accessibility to transport infrastructure. Taking into account living conditions of elderly pedestrians, contour measures were used, in order to determine accessibility as equity indicator.

  8. THE BREED TRACEABILITY OF SHEEP MEAT BY USING MOLECULAR GENETICS METHODS: PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    A. Bramante

    2011-04-01

    Full Text Available Safety and quality foods of animal origin are extremely important for consumers. The aim of this work was to evaluate the feasibility of a method to track the breed origin of sheep meat all along the production chain using molecular genetics tools. A total of 800 samples evenly distributed among seven Italian sheep breeds have been typed at 19 STR markers, together with 90 samples from both imported sheep animals and local crossbred animals withdrawn at slaughterhouses. A maximum likelihood assignment test was adopted to evaluate STR ability to allocate samples to their true breed of origin. Sarda animals were all correctly allocated, as well as more than 98% of samples from the other breeds. Only slightly worst allocation performances were observed for imported and crossbred animals. Preliminary results seem quite promising, though further analyses will be needed in order to better understand the statistical power of such an assignment test before implementation in the sheep meat production chain.

  9. Description and preliminary results of a meteorological network for high altitudes

    Science.gov (United States)

    Duran-Montejano, L.

    2003-04-01

    A high resolution meteorological network has been implemented for monitoring temperature, relative humidity and precipitation at very high altitudes. The system is made up by a specially designed “terrestrial buoy” for high altitudes of very low power requirement and great robustness. The complete system consists of seven of these terrestrial buoys installed in less than 20 Km2 and with more than one measuring point per 150 m of altitude difference. A brief description of the system is presented with some of the preliminary results, including spatial generalization of the point meteorological data to the whole domain of the network using a simple spatial interpolation algorithm and a high resolution terrain digital model in order to be used as inputs for eco-biological models.

  10. Preliminary dating results for ancient ceramics from Romania by means of thermoluminescence

    International Nuclear Information System (INIS)

    The preliminary results from dating two types of ancient ceramic from Romania by means of thermoluminescence are presented. The measurements are the first TL dating in a Romanian laboratory. Pottery collected from two Eneolithical sites (Petresti culture) and two types of Roman ceramic were investigated using the quartz inclusion technique and an additive dose procedure. The annual dose was estimated using instrumental neutron activation and the calculated values ranged between 2.7 and 3.7mGy per annum. The analysis yielded reproductible growth curves and the ages obtained range between 5321+/-257 and 5850+/-509y in good agreement with the dates assigned by archaeologists (5000-6000y) for the Neolithic samples. The ages for the Roman samples, 1790+/-125 and 1850+/-170y were also consistent with their known ages

  11. Instrumentation development for space debris optical observation system in Indonesia: Preliminary results

    Science.gov (United States)

    Dani, Tiar; Rachman, Abdul; Priyatikanto, Rhorom; Religia, Bahar

    2015-09-01

    An increasing number of space junk in orbit has raised their chances to fall in Indonesian region. So far, three debris of rocket bodies have been found in Bengkulu, Gorontalo and Lampung. LAPAN has successfully developed software for monitoring space debris that passes over Indonesia with an altitude below 200 km. To support the software-based system, the hardware-based system has been developed based on optical instruments. The system has been under development in early 2014 which consist of two systems: the telescopic system and wide field system. The telescopic system uses CCD cameras and a reflecting telescope with relatively high sensitivity. Wide field system uses DSLR cameras, binoculars and a combination of CCD with DSLR Lens. Methods and preliminary results of the systems will be presented.

  12. Radiotherapy and healing results of cervical carcinoma at the University Clinic of Freiburg during the years 1964-1973

    International Nuclear Information System (INIS)

    The most important results after 10 years of telecobalt therapy of cervical carcinoma are as follows: When compared with the years 1955-1963, no statistically significant improvement of the healing results could be obtained by introducing the telecobalt therapy. The healing results can be called very good if compared with the results of the whole world compiled in the ANNUAL REPORT. Radium between 4000 and 6000 mgh and at the same time telecobalt between 3000 and 5000 R focal dose are seen as sufficient therapeutical doses for the irradiation of cervical carcinoma. If three radium administrations were effected there were significantly less local relapses at the portio and cervix than with two administrations. Radiation hazards at the intestine showed a significant dependence on the height of the telecobalt dose. An increase in the radiation reaction at the intestine could be noticed from the rectal exposition of 2000 Rad on. (orig./MG)

  13. Multidrug chemotherapy (vincristine-bleomycin-methotrexate) followed by radiotherapy in inoperable carcinomas of the head and neck: preliminary report of a pilot study of the Radiation Therapy Oncology Group

    International Nuclear Information System (INIS)

    This is a preliminary report on the Radiation Therapy Oncology Group (RTOG) pilot study 77-08, of a combination of chemotherapy with vincristine-bleomycin-methotrexate, followed by radiotherapy, for inoperable carcinomas of the head and neck. The main objectives of the study were to determine toxicity and tumor control. Patients who were included had untreated carcinomas, with no distant metastases, and with adequate pulmonary, renal, and liver function. Forty patients were registered for the study. Chemotherapy started with vincristine--1.5 mgs/m2 (maximum of 2 mgs) by I.V. injection, followed by bleomycin drip for 48 hours (15 units/day), and then methotrexate (200 mgs/m2 divided in equal doses 6 hours apart) with folinic acid rescue. Eleven patients received one course of the stated chemotherapy; 28 were given two courses with one week rest period between them. Radical curative radiotherapy was started usually two weeks after chemotherapy. A surgical procedure was considered if the patient was found operable after receiving a dose of 5000 rad with continuous therapy or at 3000 rad with split-course therapy. The level of toxicity that resulted from this combined therapy was considered acceptable. The percentage of complete response of the primary tumor was 6% with chemotherapy; this increased to 46% after irradiation, and to 65% when surgery was added

  14. Cosmetic results after breast conserving carcinoma treatment in patients with intramammarian seromas

    International Nuclear Information System (INIS)

    Introduction: There were 373 patients irradiated after breast conserving carcinoma treatment. A planning computed tomography revealed in 97 of these patients seromas and tissue defects exceeding 2 cm in diameter. The cosmetic results in those patients and the impact of seromas herein had to be evaluated. Patients and methods: Mean age was 59 years. A quadrant resection was performed in 17,5 percent of the patients, a segmental resection in 27,8 percent and a tumour excision in 54,6 percent. Radiation therapy was applied with the linear accelerator and 6 MeV photons up to a total dose in the residual breast of 50 Gy followed by a boost dose to the former tumour bed on 10 Gy. A distinct evaluation and documentation of therapy related side effects and the resulting cosmesis was done in 51 patients. Results: In all the examined seroma patients there were moderate acute skin reactions grade 1 to 3. As late effects in 82,3 percent scar indurations were noticed. At the skin 51 percent showed enhanced pigmentation, 68,6 percent atrophia and only 11 percent teleangiectasia. Subcutaneous fibrosis occurred in 56,9 percent of the patients, 78,4 percent of the women had breast asymmetries. In 41,2 percent there were a lymphedema subcutaneously, in 72,5 percent impaired sensibility. The overall cosmetic result documented with a 5 point score was 'very good' (score 1) in 19,6 percent and 'good' (score 2) in 33,3 percent, 37,3 percent were 'satisfactory' (score 3) and 9,8 percent 'bad' (score 4) respectively. No 'very bad' results (score 5) were seen. Conclusions: The cosmetic results in the examined group of seroma and hematoma patients were inferior to those reported in the literature. We conclude that post-operative seroma and hematoma have an adverse effect on the resulting cosmesis and that their frequency and extent have to be reduced in future by the responsible surgeons. (orig.)

  15. Preliminary results of a lidar-dial integrated system for the automatic detection of atmospheric pollutants

    Science.gov (United States)

    Gaudio, P.; Gelfusa, M.; Richetta, M.

    2012-11-01

    In the last decades, atmospheric pollution in urban and industrial areas has become a major concern of both developed and developing countries. In this context, surveying relative large areas in an automatic way is an increasing common objective of public health organisations. The Lidar-Dial techniques are widely recognized as a cost-effective approach to monitor large portions of the atmosphere and, for example, they have been successful applied to the early detection of forest fire. The studies and preliminary results reported in this paper concern the development of an integrated Lidar-Dial system able to detect sudden releases in air of harmful and polluting substances. The propose approach consists of continuous monitoring of the area under surveillance with a Lidar type measurement (by means of a low cost system). Once a significant increase in the density of a pollutant is revealed, the Dial technique is used to identify the released chemicals. In this paper, the specifications of the proposed station are discussed. The most stringent requirement is the need for a very compact system with a range of at least 600-700 m. Of course, the optical wavelengths must be in an absolute eye-safe range for humans. A conceptual design of the entire system is described and the most important characteristic of the main elements are provided. In particular the capability of the envisaged laser sources, Nd:YAG and CO2 lasers, to provide the necessary quality of the measurements is carefully assessed. Since the detection of dangerous substances must be performed in an automatic way, the monitoring station will be equipped with an adequate set of control and communication devices for independent autonomous operation. The results of the first preliminary tests illustrate the potential of the chosen approach.

  16. Robotic image-guided reirradiation of lateral pelvic recurrences: preliminary results

    International Nuclear Information System (INIS)

    The first-line treatment of a pelvic recurrence in a previously irradiated area is surgery. Unfortunately, few patients are deemed operable, often due to the location of the recurrence, usually too close to the iliac vessels, or the associated surgical morbidity. The objective of this study is to test the viability of robotic image-guided radiotherapy as an alternative treatment in inoperable cases. Sixteen patients previously treated with radiotherapy were reirradiated with CyberKnife® for lateral pelvic lesions. Recurrences of primary rectal cancer (4 patients), anal canal (6), uterine cervix cancer (4), endometrial cancer (1), and bladder carcinoma (1) were treated. The median dose of the previous treatment was 45 Gy (EqD2 range: 20 to 96 Gy). A total dose of 36 Gy in six fractions was delivered with the CyberKnife over three weeks. The responses were evaluated according to RECIST criteria. Median follow-up was 10.6 months (1.9 to 20.5 months). The actuarial local control rate was 51.4% at one year. Median disease-free survival was 8.3 months after CyberKnife treatment. The actuarial one-year survival rate was 46%. Acute tolerance was limited to digestive grade 1 and 2 toxicities. Robotic stereotactic radiotherapy can offer a short and well-tolerated treatment for lateral pelvic recurrences in previously irradiated areas in patients otherwise not treatable. Efficacy and toxicity need to be evaluated over the long term, but initial results are encouraging

  17. Pre- and post-radiotherapy MRI results as a predictive model for response in laryngeal carcinoma

    NARCIS (Netherlands)

    Ljumanovic, Redina; Langendijk, Johannes A.; Hoekstra, Otto S.; Knol, Dirk L.; Leemans, C. Rene; Castelijns, Jonas A.

    2008-01-01

    The purpose was to determine if pre-radiotherapy (RT) and/or post-radiotherapy magnetic resonance (MR) imaging can predict response in patients with laryngeal carcinoma treated with RT. Pre- and post-RT MR examinations of 80 patients were retrospectively reviewed and associated with regard to local

  18. Vegetable and fruit consumption and risk of renal cell carcinoma: Results from the Netherlands cohort study

    NARCIS (Netherlands)

    Dijk, B.A.C. van; Schouten, L.J.; Kiemeney, L.A.L.M.; Goldbohm, R.A.; Brandt, P.A. van den

    2005-01-01

    Vegetable and fruit consumption is generally inversely associated with various cancer types, including renal cell carcinoma (RCC). The Netherlands cohort study on diet and cancer (NLCS) consists of 120,852 men and women, aged 55-69 years, who filled out a self-administered questionnaire that include

  19. Vegetable and fruit consumption and risk of renal cell carcinoma: results from the Netherlands cohort study.

    NARCIS (Netherlands)

    Dijk, B.A. van; Schouten, L.J.; Kiemeney, L.A.L.M.; Goldbohm, R.A.; Brandt, P.A. van den

    2005-01-01

    Vegetable and fruit consumption is generally inversely associated with various cancer types, including renal cell carcinoma (RCC). The Netherlands cohort study on diet and cancer (NLCS) consists of 120,852 men and women, aged 55-69 years, who filled out a self-administered questionnaire that include

  20. Intensity-modulated radiation therapy for T4 nasopharyngeal carcinoma. Treatment results and locoregional

    Energy Technology Data Exchange (ETDEWEB)

    Chen, J.L.Y.; Tsai, C.L.; Chen, W.Y.; Wang, C.W. [National Taiwan Univ. Hospital, Taipei (China). Div. of Radiation Oncology; Huang, Y.S.; Chen, Y.F. [National Taiwan Univ. Hospital, Taipei (China). Dept. of Medical Imaging; Kuo, S.H. [National Taiwan Univ. Hospital, Taipei (China). Div. of Radiation Oncology; National Taiwan Univ. College of Medicine, Taipei (China). Graduate Inst. of Clinical Medicine; Hong, R.L. [National Taiwan Univ. Hospital, Taipei (China). Div. of Medical Oncology; Ko, J.Y.; Lou, P.J. [National Taiwan Univ. Hospital, Taipei (China). Dept. of Otolaryngology

    2013-12-15

    Purpose: The purpose of this work was to examine outcomes in patients with T4 nasopharyngeal carcinoma (NPC) treated with intensity-modulated radiation therapy (IMRT). Methods and materials: Between 2007 and 2010, 154 patients with nonmetastatic T4 NPC were treated with IMRT to a total dose of 70 Gy in 33-35 fractions. In addition, 97 % of patients received concurrent platinum-based chemotherapy. The median follow-up time was 52.8 months. Results: The rates of 5-year actuarial locoregional control, distant metastasis-free survival, progression free-survival, and overall survival (OS) were 81.2, 72.2, 61.9, and 78.1 %, respectively. A total of 27 patients had locoregional recurrence: 85.2 % in-field failures, 11.1 % marginal failures, and 3.7 % out-of-field failures. Fourteen patients with locoregional recurrence received aggressive treatments, including nasopharyngectomy, neck dissection, or re-irradiation, and the 5-year OS rate tended to be better (61.9 %) compared to those receiving conservative treatment (32.0 %, p = 0.051). In patients treated with 1 course of radiotherapy, grade {>=} 3 toxicities of ototoxicity, neck fibrosis, xerostomia, epistaxis, and radiographic temporal lobe necrosis occurred in 18.2, 9.8, 6.3, 2.1, and 5.6 % of patients, respectively. Increased ototoxicity, osteonecrosis, severe nasal bleeding, and temporal necrosis were observed in patients treated by re-irradiation. Conclusion: IMRT offers good locoregional control in patients with T4 NPC. For patients with locoregional recurrence after definitive radiotherapy, aggressive local treatment may be considered for a better outcome. (orig.)

  1. ¹⁸F-FDG PET metabolic parameters and MRI perfusion and diffusion parameters in hepatocellular carcinoma: a preliminary study.

    Directory of Open Access Journals (Sweden)

    Sung Jun Ahn

    Full Text Available OBJECTIVES: Glucose metabolism, perfusion, and water diffusion may have a relationship or affect each other in the same tumor. The understanding of their relationship could expand the knowledge of tumor characteristics and contribute to the field of oncologic imaging. The purpose of this study was to evaluate the relationships between metabolism, vasculature and cellularity of advanced hepatocellular carcinoma (HCC, using multimodality imaging such as ¹⁸F-FDG positron emission tomography (PET, dynamic contrast enhanced (DCE-MRI, and diffusion weighted imaging(DWI. MATERIALS AND METHODS: Twenty-one patients with advanced HCC underwent ¹⁸F-FDG PET, DCE-MRI, and DWI before treatment. Maximum standard uptake values (SUV(max from ¹⁸F-FDG-PET, variables of the volume transfer constant (K(trans from DCE-MRI and apparent diffusion coefficient (ADC from DWI were obtained for the tumor and their relationships were examined by Spearman's correlation analysis. The influence of portal vein thrombosis on SUV(max and variables of K(trans and ADC was evaluated by Mann-Whitney test. RESULTS: SUV(max showed significant negative correlation with K(trans(max (ρ = -0.622, p = 0.002. However, variables of ADC showed no relationship with variables of K(trans or SUV(max (p>0.05. Whether portal vein thrombosis was present or not did not influence the SUV max and variables of ADC and K(trans (p>0.05. CONCLUSION: In this study, SUV was shown to be correlated with K(trans in advanced HCCs; the higher the glucose metabolism a tumor had, the lower the perfusion it had, which might help in guiding target therapy.

  2. Preliminary results on photometric properties of materials at the Sagan Memorial Station, Mars

    Science.gov (United States)

    Johnson, J. R.; Kirk, R.; Soderblom, L.A.; Gaddis, L.; Reid, R.J.; Britt, D.T.; Smith, P.; Lemmon, M.; Thomas, N.; Bell, J.F., III; Bridges, N.T.; Anderson, R.; Herkenhoff, K. E.; Maki, J.; Murchie, S.; Dummel, A.; Jaumann, R.; Trauthan, F.; Arnold, G.

    1999-01-01

    Reflectance measurements of selected rocks and soils over a wide range of illumination geometries obtained by the Imager for Mars Pathfinder (IMP) camera provide constraints on interpretations of the physical and mineralogical nature of geologic materials at the landing site. The data sets consist of (1) three small "photometric spot" subframed scenes, covering phase angles from 20?? to 150??; (2) two image strips composed of three subframed images each, located along the antisunrise and antisunset lines (photometric equator), covering phase angles from ???0?? to 155??; and (3) full-image scenes of the rock "Yogi," covering phase angles from 48?? to 100??. Phase functions extracted from calibrated data exhibit a dominantly backscattering photometric function, consistent with the results from the Viking lander cameras. However, forward scattering behavior does appear at phase angles >140??, particularly for the darker gray rock surfaces. Preliminary efforts using a Hapke scattering model are useful in comparing surface properties of different rock and soil types but are not well constrained, possibly due to the incomplete phase angle availability, uncertainties related to the photometric function of the calibration targets, and/or the competing effects of diffuse and direct lighting. Preliminary interpretations of the derived Hapke parameters suggest that (1) red rocks can be modeled as a mixture of gray rocks with a coating of bright and dark soil or dust, and (2) gray rocks have macroscopically smoother surfaces composed of microscopically homogeneous, clear materials with little internal scattering, which may imply a glass-like or varnished surface. Copyright 1999 by the American Geophysical Union.

  3. Results of conservative surgery and radiation for mammographically detected ductal carcinoma in situ (DCIS)

    International Nuclear Information System (INIS)

    Purpose: The role of conservative surgery and radiation for mammographically detected ductal carcinoma in situ (DCIS) is controversial. In particular, there is little data for outcome with radiation in a group of patients comparable to those treated with local excision and surveillance (mammographic calcifications ≤2.5cm, negative resection margins, negative post biopsy mammogram). This study reports outcome of conservative surgery and radiation for mammographically detected DCIS with an emphasis on results in patients considered candidates for excision alone. Methods and Materials: >From 1983 to 1992, 110 women with mammographically detected DCIS (77% calcifications ± mass) and no prior history of breast cancer underwent needle localization and biopsy with (55%) or without a re excision and radiation. Final margins of resection were negative in 62%, positive 7%, close 11%, and unknown 20%. The median patient age was 56 years. The most common histologic subtype was comedo (54%), followed by cribriform (22%). The median pathologic tumor size was 8 mm (range 2 mm to 5 cm). Forty-seven percent of patients with calcifications only had a negative post biopsy mammogram prior to radiation. Radiation consisted of treatment to the entire breast (median 50.00 Gy) and a boost to the primary site (97%) for a median total dose of 60.40 Gy. Results: With a median follow-up of 5.3 years, three patients developed a recurrence in the treated breast. The median interval to recurrence was 8.8 years and all were invasive cancers. Two (67%) occurred outside the initial quadrant. The 5- and 10-year actuarial rates of recurrence were 1 and 15%. Cause-specific survival was 100% at 5 and 10 years. Contralateral breast cancer developed in two patients. There were too few failures for statistical significance to be achieved with any of the following factors: patient age, family history, race, mammographic findings, location primary, pathologic size, histologic subtype, re excision, or

  4. Resultados oncológicos da laringectomia parcial no carcinoma glótico inicial Oncologic results of the partial laryngectomy for early glottic carcinoma

    Directory of Open Access Journals (Sweden)

    Otávio Alberto Curioni

    2002-10-01

    for 5 years of 65%-70%. Aim: Evaluation of the results after partial laringectomy for early glottic squamous cell carcinoma. Study design: Clinical retrospective. Material and Method: Retrospective analysis of the 59 patients' handbook was accomplished submitted to the partial laringectomy. There were excluded patients with previous treatment, tumor extension larger than 10 mm below the glottis, lesions with macroscopicextension for vestibular folds and lesions with decrease of the mobility vocal cords laryngoscopy and follow-up of 36 months or more. Results: 12 patients (20,3% presented recurrence, being 1 a regional recurrence (1,7% and 11 local recurrences (18,6%, with surgical rescue (total laringectomy and oncologic control in 75% of those cases. Severe complications (glottic stenosis and aspiration happened in only 2 patients (3,4%. Conclusions: The partial laringectomy is safe and an effective procedure for the treatment of majority of early glottic carcinoma. In addition, for its versatility, check safety in the oncologic radically and make possible, also, the functional readaptation for the patient

  5. Poor results with technetium-99m (V) DMS and iodine-131 MIBG in the imaging of medullary thyroid carcinoma

    International Nuclear Information System (INIS)

    The value of [/sup 99m/Tc(V)]DMS and [131I]MIBG in imaging medullary carcinoma of the thyroid was investigated in five patients. Results with [/sup 99m/Tc(V)]DMS were negative in all five patients as well as with [131I]MIBG in four patients; however, there was significant tumor uptake in one patient with [131I]MIBG

  6. IBIS preliminary results on Cygnus X-1 spectral and temporal characteristics

    CERN Document Server

    Bazzano, A; Capitanio, F; Santo, M D; Ubertini, P; Zdziarski, A A; Cocco, G D; Falanga, M; Goldoni, P; Goldwurm, A; Laurent, P; Lebrun, F; Malaguti, G; Segreto, A

    2003-01-01

    We report preliminary results of a broadband spectral and temporal study of the black-hole binary Cyg X-1 performed with the IBIS telescope. Cyg X-1 was the first pointed celestial target of IBIS during the INTEGRAL Performance and Verification Phase, 2002 Nov.-Dec., for a total observing time of 2 Ms in both staring and dithering mode. Here, we report on only the staring, on-axis, observation performed in a stable instrument configuration. During the observing period the source was in its characteristic low/hard state, in which a few flares and dips have been detected. The IBIS/ISGRI results demonstrate that the INTEGRAL observatory offers a unique capability for studying correlations between hardness and/or flux in different bands over a wide photon energy range. One of our new results is finding that the hardness-flux correlation changes the sign twice over the 20-220 keV; first from positive to negative at 50 keV, and then back to positive at 120 keV. The former change appears to be due to the spectral cu...

  7. The genetic variability of the Podolica cattle breed from the Gargano area. Preliminary results

    Directory of Open Access Journals (Sweden)

    Dario Cianci

    2010-01-01

    Full Text Available The Podolica cattle breed is autochthonous of Southern Italy and denoted by its particular rusticity. This study presents the preliminary results of the genetic characterization of the Podolica breed using DNA STR markers. A total of 20 microsatellite loci were analysed in 79 individuals reared in the Gargano area. Number of polymorphisms, allele fre- quencies, deviations from Hardy-Weinberg proportions, linkage disequilibrium between loci and genetic similarities between animals were calculated. The results showed a high deficiency of heterozygotes, the observed mean of het- erozygosis being 0.449, whereas the expected mean was 0.766. Many markers showed also deviations from the Hardy- Weinberg proportions and significant linkage disequilibrium between loci. However the genetic similarity within the pop- ulation was low (0.281 and the average number of alleles per locus was high (10, representing a high genetic vari- ability. In order to explain these results, a stratification of the breed in sub-populations with a high interior genetic homo- geneity but markedly differentiated one from each other could be hypothesized; this situation probably derived from non- random mating within each herd (consanguinity and from the lack of exchange of genetic material between the herds. A further study is needed on a wider sample and extending the analysis to FAO-ISAG microsatellite panel in order to con- firm this hypothesis. This could eventually provide the information necessary for the correct management of the repro- ductive schemes and for genomic traceability of meat production.

  8. Preliminary results of local earthquake tomography around Bali, Lombok, and Sumbawa regions

    Energy Technology Data Exchange (ETDEWEB)

    Nugraha, Andri Dian, E-mail: nugraha@gf.itb.ac.id; Puspito, Nanang T; Yudistira, Tedi [Global Geophysical Reserach Group, Faculty of Mining and Petroleum Engineering, Institute of Technology Bandung, JlGanesa 10, Bandung, 40132 (Indonesia); Kusnandar, Ridwan; Sakti, Artadi Pria [Meteorological, Climatological, and Geophysical Agency (MCGA) of Indonesian, Jakarta (Indonesia)

    2015-04-24

    Bali, Sumbawa, and Lombok regions are located in active tectonic influence by Indo-Australia plate subducts beneath Sunda plate in southern part and local back-arc thrust in northern part the region. Some active volcanoes also lie from eastern part of Java, Bali, Lombok and Sumbawa regions. Previous studies have conducted subsurface seismic velocity imaging using regional and global earthquake data around the region. In this study, we used P-arrival time from local earthquake networks compiled by MCGA, Indonesia within time periods of 2009 up to 2013 to determine seismic velocity structure and simultaneously hypocenter adjustment by applying seismic tomography inversion method. For the tomographic inversion procedure, we started from 1-D initial velocity structure. We evaluated the resolution of tomography inversion results through checkerboard test and calculating derivative weigh sum. The preliminary results of tomography inversion show fairly clearly high seismic velocity subducting Indo-Australian and low velocity anomaly around volcano regions. The relocated hypocenters seem to cluster around the local fault system such as back-arc thrust fault in northern part of the region and around local fault in Sumbawa regions. Our local earthquake tomography results demonstrated consistent with previous studies and improved the resolution. For future works, we will determine S-wave velocity structure using S-wave arrival time to enhance our understanding of geological processes and for much better interpretation.

  9. Facial emotional recognition in schizophrenia: preliminary results of the virtual reality program for facial emotional recognition

    Directory of Open Access Journals (Sweden)

    Teresa Souto

    2013-01-01

    Full Text Available BACKGROUND: Significant deficits in emotional recognition and social perception characterize patients with schizophrenia and have direct negative impact both in inter-personal relationships and in social functioning. Virtual reality, as a methodological resource, might have a high potential for assessment and training skills in people suffering from mental illness. OBJECTIVES: To present preliminary results of a facial emotional recognition assessment designed for patients with schizophrenia, using 3D avatars and virtual reality. METHODS: Presentation of 3D avatars which reproduce images developed with the FaceGen® software and integrated in a three-dimensional virtual environment. Each avatar was presented to a group of 12 patients with schizophrenia and a reference group of 12 subjects without psychiatric pathology. RESULTS: The results show that the facial emotions of happiness and anger are better recognized by both groups and that the major difficulties arise in fear and disgust recognition. Frontal alpha electroencephalography variations were found during the presentation of anger and disgust stimuli among patients with schizophrenia. DISCUSSION: The developed program evaluation module can be of surplus value both for patient and therapist, providing the task execution in a non anxiogenic environment, however similar to the actual experience.

  10. Polyurethane-Covered Self-expandable Nitinol Stent for Malignant Biliary Obstruction: Preliminary Results

    International Nuclear Information System (INIS)

    Purpose: To evaluate the immediate and long-term results in ten patients with malignant biliary obstruction using a polyurethane-covered, self-expandable nitinol stent.Methods: A nitinol stent, fully covered with high-elasticity polyurethane, with an unconstrained diameter of 10 mm and a total length of 60-80 mm, was placed transhepatically under fluoroscopic guidance in ten patients. The length of the biliary obstruction varied between 30-50 mm. The follow-up examination included a clinical assessment, serum bilirubin measurement, and ultrasound examinations at one-month intervals in all patients. Results: Initial stent deployment was successful in eight patients. Two patients experienced proximal migration,which was solved by insertion of two, uncovered Wallstents. One patient had the stent removed after two weeks because of severe nausea and vomiting. One patient had delayed migration of the covered stent after 40 weeks. The follow-up duration was 3-40 weeks (Mean: 16.9 weeks). Seven patients died(3-26 weeks) and three patients survived (24-40 weeks). The bilirubin measurements in all patients had significantly decreased one week after stent insertion. The levels of amylase and lipase had did not increase after stent insertion. Conclusions: Apolyurethane-covered, self-expandable nitinol stent can be used effectively and safely in the treatment of malignant biliary obstruction. The preliminary results are favorable, but there is a need for further large studies to determine both long-term survival and patency

  11. Preliminary results of local earthquake tomography around Bali, Lombok, and Sumbawa regions

    International Nuclear Information System (INIS)

    Bali, Sumbawa, and Lombok regions are located in active tectonic influence by Indo-Australia plate subducts beneath Sunda plate in southern part and local back-arc thrust in northern part the region. Some active volcanoes also lie from eastern part of Java, Bali, Lombok and Sumbawa regions. Previous studies have conducted subsurface seismic velocity imaging using regional and global earthquake data around the region. In this study, we used P-arrival time from local earthquake networks compiled by MCGA, Indonesia within time periods of 2009 up to 2013 to determine seismic velocity structure and simultaneously hypocenter adjustment by applying seismic tomography inversion method. For the tomographic inversion procedure, we started from 1-D initial velocity structure. We evaluated the resolution of tomography inversion results through checkerboard test and calculating derivative weigh sum. The preliminary results of tomography inversion show fairly clearly high seismic velocity subducting Indo-Australian and low velocity anomaly around volcano regions. The relocated hypocenters seem to cluster around the local fault system such as back-arc thrust fault in northern part of the region and around local fault in Sumbawa regions. Our local earthquake tomography results demonstrated consistent with previous studies and improved the resolution. For future works, we will determine S-wave velocity structure using S-wave arrival time to enhance our understanding of geological processes and for much better interpretation

  12. Impulsivity in Multiplayer Online Battle Arena Gamers: Preliminary Results on Experimental and Self-Report Measures.

    Science.gov (United States)

    Nuyens, Filip; Deleuze, Jory; Maurage, Pierre; Griffiths, Mark D; Kuss, Daria J; Billieux, Joël

    2016-06-01

    Background and aims Multiplayer Online Battle Arena (MOBA) games have become the most popular type of video games played worldwide, superseding the playing of Massively Multiplayer Online Role-Playing Games and First-Person Shooter games. However, empirical studies focusing on the use and abuse of MOBA games are still very limited, particularly regarding impulsivity, which is an indicator of addictive states but has not yet been explored in MOBA games. In this context, the objective of the present study is to explore the associations between impulsivity and symptoms of addictive use of MOBA games in a sample of highly involved League of Legends (LoL, currently the most popular MOBA game) gamers. Methods Thirty-six LoL gamers were recruited and completed both experimental (Single Key Impulsivity Paradigm) and self-reported impulsivity assessments (s-UPPS-P Impulsive Behavior Scale, Barratt Impulsiveness Scale), in addition to an assessment of problematic video game use (Problematic Online Gaming Questionnaire). Results Results showed links between impulsivity-related constructs and signs of excessive MOBA game involvement. Findings indicated that impaired ability to postpone rewards in an experimental laboratory task was strongly related to problematic patterns of MOBA game involvement. Although less consistent, several associations were also found between self-reported impulsivity traits and signs of excessive MOBA game involvement. Conclusions Despite these results are preliminary and based upon a small (self-selected) sample, the present study highlights potential psychological factors related to the addictive use of MOBA games. PMID:27156376

  13. Preliminary results on timing properties of CVD diamond detectors for MIPs

    International Nuclear Information System (INIS)

    Due to the large band gap, radiation hardness and fast charge collection, the CVD diamond detectors have been investigated and developed in the last decade for possible use as trackers in high luminosity hadron colliders. Recently they have been successfully used for high resolution 'time zero' detectors in heavy ion experiments. The results of preliminary tests on timing properties of CVD diamond detectors for minimum ionizing particles (MIPs) are reported in this contribution. A unpolished CVD sample of 700 μm with a collection distance of about 60 μm was used for these measurements. All the reported results have been obtained using a 90 Sr β source and an applied electric field of ED = 1 V/μm. A low noise, 50 Ω, 3 GHz amplifier developed at GSI has been used. The reference time signal was delivered by a NE102 plastic scintillator. A figure is given showing amplitude - time of flight correlations. An amplitude dependence of the maxima in the time distribution, a reduction of the dispersion going to larger amplitudes and an asymmetry of the distributions with the larger tail towards higher values of the time of flight can be observed. A time spectrum for CVD amplitudes larger than channel 900 is also given. One TDC channel corresponds to 60 psec. The Gaussian fit has been done on selected window such to enhance the contribution of the left side of the time spectra, where the tail is less pronounced. If we subtract quadratically the time resolution of the plastic scintillator estimated to be ≅ 95 psec, a CVD time resolution of 95 psec is obtained.Taking into account the quality of the CVD diamond used in the present tests relative to the performance reached during the last period, a factor of at least 4 in the amplitude can be easily gained. In such conditions we consider that the preliminary results reported here are quite convincing that using high quality CVDs and appropriate electronics for signal processing (including probably some corrections), CVD

  14. The Leeds results for radiotherapy in HBO for carcinoma of the head and neck

    International Nuclear Information System (INIS)

    Follow-up data at five years are reported for 24 patients with squamous cell carcinoma of the head and neck, included in a randomised prospective MRC study of radiotherapy in hyperbaric oxygen (10 fractions) or air (15 or 20 fractions). Although few, the data show a significant gain in local control (P < 0.001) and survival (P < 0.05) with the use of hyperbaric oxygen but no increased tissue reactions or morbidity. (author)

  15. Induction of cytotoxic T lymphocytes primed with Tumor RNA-loaded Dendritic Cells in esophageal squamous cell carcinoma: preliminary step for DC vaccine design

    International Nuclear Information System (INIS)

    Dendritic Cells (DC) are potent antigen presenting cells with the ability to prime naïve T cells and convert them to cytotoxic T-lymphocytes (CTL). We evaluated the capability of autologous DCs transfected with total tumor and normal RNA to induce cytotoxic CTL as the preliminary step to design a DC-based vaccine in the esophageal squamous cell carcinoma (ESCC). Monocytes-derived DCs were electroporated with either total tumor RNA or normal RNA. T cells were then primed with tumor RNA transfected DCs and lytic effects of the generated CTL were measured with Cytotoxicity assay and IFN-γ Release Elispot assay. Cytotoxicity was induced against DCs loaded with tumoral RNA (%24.8 ± 5.2 SEM) while in normal RNA-loaded DCs, it was minimal (%6.1 ± 2.4 SEM) and significantly lower (p < 0.05). INF-γ secretion was more than 2-folds higher in tumoral RNA-loaded DCs when compared with normal RNA-loaded DCs (p < 0.05). Electroporating DCs with tumor RNA generated tumor antigen presenting cells which in turn enhanced cytotoxic effects of the T cells against ESCC. This may be a useful autologous ex vivo screening tool for confirming the lytic effects of primed T cells on tumors and evaluate probable further adverse effects on noncancerous tissues. These data provide crucial preliminary information to establish a total tumor RNA-pulsed DC vaccine therapy of ESCC

  16. Preliminary performance results for the ATLAS RPC test stand in Lecce

    International Nuclear Information System (INIS)

    We present here a preliminary performance analysis of the ATLAS RPC tested at the Lecce cosmic ray testing facility. In this paper we define the operating working point for our detectors and show the distribution of the principal operating parameters

  17. 78 FR 21107 - Circular Welded Carbon Steel Pipes and Tubes from Turkey: Preliminary Results of Countervailing...

    Science.gov (United States)

    2013-04-09

    ... Steel Pipes and Tubes from Turkey (Preliminary Decision Memorandum) from Edward C. Yang, Senior Director... 5084: Allocation of Free Land and Purchase of Land for less than Adequate Remuneration (LTAR) F....

  18. Stage IB carcinoma of the cervix, the Norwegian radium hospital, 1968--1970: results of treatment annd major complications

    Energy Technology Data Exchange (ETDEWEB)

    Martimbeau, P.W.; Kjorstad, K.E.; Kolstad, P.

    1978-06-15

    Different methods of treatment have been debated over the years for Stage IB carcinoma of the cervix, especially in view of the results and complications. We have reviewed the experience of the Norwegian Radium Hospital for carcinoma of the cervix, Stage IB, for the years 1968, 1969, and 1970; most of the patients receive preoperative intrauterine and intravaginal radium, followed by radical hysterectomy and pelvic lymphadenectomy; if the nodes are involved, they also receive external pelvic irradiation. During this period, 437 patients had Stage IB; the 5 year survival was 80.2 per cent (not corrected). We focused our attention on lymphedema following such a method of treatment; of 402 patients operated upon, 23.4% developed lymphedema ranging from mild to moderate to severe; 20 patients (5%) had severe lymphedema; factors involved are analyzed.

  19. Rhenium-188 Lipiodol Therapy of Hepatocellular Carcinoma: Results of a multicentre-multinational study

    International Nuclear Information System (INIS)

    Full text: A multi-centre study was sponsored by the IAEA to assess the safety and efficacy of trans-arterial Rhenium-188 HDD Lipiodol in the treatment of inoperable Hepatocellular Carcinoma. The radioconjugate was prepared by using an HDD kit and Lipiodol. Over three years, 185 patients received at least one treatment. The dose administered was based on radiation absorbed dose to critical normal organs, calculated following a ''scout'' dose (approximately 4 mCi) of radioconjugate. The organs at greatest risk for radiation toxicity are the liver, the lung and the bone marrow. An Excel spreadsheet was used to determine maximum tolerated activity, defined as the amount of radioactivity calculated to deliver no more than 12 Gy to lungs, 30 Gy to liver, or 1.5 Gy to bone marrow. A single treatment was given to 134 patients, 42 patients received two doses, 8 received three and one patient received four treatments. The total injected activity including the scout dose during the first treatment ranged from 21 to 364 mCi (average 108 mCi). Patients were followed for at least l2 weeks after therapy. The clinical parameters evaluated included toxicity, response as determined objectively by contrast enhanced computed tomography, palliation of symptoms, overall survival, performance status (Karnofsky), and hepatic function (Child's classification). Liver function tests, serum alpha-fetoprotein (AFP) levels and complete blood counts were done at each follow-up visit. Side effects were minimal and usually presented as loss of appetite, right hypochondrial discomfort and low-grade fever. Liver function tests at 24 and 72 hours showed no significant changes and complete blood counts at 1 week, 4 weeks and 12 weeks showed no changes (no bone marrow suppression). Data on largest tumour diameter after therapy and/or tumour response as evaluated from CT scans are available for 88 patients. Complete disappearance of tumour was recorded in 3 (3%), partial response in 19 (22%), stable

  20. Holocene evolution and sedimentation rate of Alikes Lagoon, Zakynthos island, Western Greece - preliminary results

    Science.gov (United States)

    Avramidis, P.; Kontopoulos, N.

    2009-03-01

    In the present study we present preliminary results of Zakynthos Alikes lagoon, which is one of the most seismically active regions of Greece. In order to estimate - interpret the Holocene evolution of the area and to reconstruct the palaeonvironmental changes, we based on the data of a 21 m sediment core. Sediment types, structure, colour, as well as contact depths and bed characteristics, were recorded in the field. Standarised sedimentological analysis were carried out, on 46 samples including grain size analysis, calculation of moment measures, and micro- and molluscan fossils of 17 selected samples. Moreover, radiocarbon age determinations have been made on individual Cardium shells from two horizons and whole - core Magnetic Susceptibility (MS) measurements were taken. The interpretation of depositional environments suggests a coastal environment (restricted-shallow) with reduced salinity such as a lagoon margin and in a tidal flat and/or marsh particularly. The maximum age of the study sediments is about 8500 BP. The rate of sedimentation between 8280 BP and 5590 BP was 5.3 mm/yr and between 5590 BP and modern times 1.03 mm/yr. The rate of sedimentation was higher until mid-Holocene while decrease after to 1.03 mm/yr, results which are similar to other coastal areas of western Greece.

  1. Holocene evolution and sedimentation rate of Alikes Lagoon, Zakynthos island, Western Greece: preliminary results

    Science.gov (United States)

    Avramidis, P.; Kontopoulos, N.

    2009-07-01

    In the present study we present preliminary results from Alikes lagoon in Zakynthos island, an area that is one of the most seismically active regions of Greece. In order to estimate - interpret the Holocene evolution of the area and to reconstruct the palaeoenvironmental changes, we based on data derived from a 21 m sediment core. Sediment types, structure, colour, as well as contact depths and bed characteristics were recorded in the field. Standarised sedimentological analysis was carried out, on 46 samples including grain size analysis, calculation of moment measures, and micro- and molluscan fossils of 17 selected samples. Moreover, radiocarbon age determinations have been made on individual Cardium shells from two horizons and whole - core Magnetic Susceptibility (MS) measurements were taken. The interpretation of depositional environments suggests a coastal environment (restricted-shallow) with reduced salinity such as a lagoon margin and in a tidal flat and/or marsh particularly. The maximum age of the studied sediments is about 8500 BP. The rate of sedimentation between 8280 BP while 5590 BP was 5.3 mm/yr and between 5590 BP and modern times is on the order of 1.03 mm/yr. These sedimentation rates results are similar to other coastal areas of western Greece.

  2. Preliminary results of a balloon flight of the solar disk sextant

    Science.gov (United States)

    Maier, E.; Twigg, L.; Sofia, S.

    1992-01-01

    Preliminary results of a balloon flight on October 11, 1991, of the solar disk sextant (SDS) experiment are reported. The SDS is an instrument which measures the solar diameter at different orientations with respect to the solar polar axis. Fitting straight lines through two fixed-angle data sets with time as the independent variable yields slopes of (7.1 +/ - 1.5) x 10 exp -3 and (6.7 +/- 1.6) x 10 exp -3/mas s, consistent with the value of 6.47 x 10 exp -3/mas s expected from the earth's approach to the sun due to the orbital motion toward perihelion. Upon the instrument's rotation on its axis a sinusoidal component of the diameter measurement was observed in each rotation cycle, with a variable amplitude of about 150 mas. The present result is epsilon of (5.6 +/- 6.3) x 10 exp -6, about 30 deg offset from the polar-equator position. The absolute diameter obtained by means of the FFT definition is found to be 1919.269 +/- 0.240 arcsec or 1919.131 +/- 0.240 arcsec, depending on the orientation mode of the measurement.

  3. Preliminary results of a national quality audit programme in radiotherapy services in Cuba

    International Nuclear Information System (INIS)

    The current state of radiotherapy in Cuba has allowed to pass to a superior stage in the process of quality assurance, the establishment of a National Quality Audit Program (PNAC). The National Control Center for Medical Devices, as national regulator entity for the control and supervision of the medical devices of the National Health System, is responsible for the implementation of this program. This paper presents the preliminary results of the execution of the PNAC in teletherapy services with isotopic units of 60Co. The audits were carried out according to the methodology settled down in the normalized procedure of operation of the PNAC. The physical aspects related with the treatment were audited, such as: the installation and unit's safety, mechanical and dosimetric aspects of the treatment unit and organizational aspects of the institution quality assurance program. Also carried out, in the clinical aspect, verifications of cases type planned by the qualified personnel of the service. The results corresponding to the determination of the reference dose for each institution were compared with those obtained in a postal audit with the International Atomic Energy Agency. These first audits allowed to evaluate the performance of the institutions' program of quality assurance and a feedback for the setting about to the PNAC. (author)

  4. Application of a PCR method for the diagnosis of ulcerative enteritis: preliminary results

    Directory of Open Access Journals (Sweden)

    Fabrizio Agnoletti

    2010-01-01

    Full Text Available Ulcerative enteritis or “quail disease” is an acute clostridial infection of young birds reported in many avian species, chicken and turkey included. Clostridium colinum is the causative agent of ulcerative enteritis and because of the difficulties bound to the isolation and identification of this bacterium by means of classic bacteriological techniques, its detection appears very hard and the prevalence of this disease could be underestimated. To investigate the diffusion of C. colinum in enteric disease of birds, a recently developed PCR protocol was applied to 42 cultural broths previously inoculated with organs and intestinal samples collected from diseased subjects. PCR-positive broths were cultivated to attempt the isolation of C. colinum. Samples collected from positive birds were subjected to histological examinations. 4 birds (3 broilers chickens and 1 pigeon resulted PCR-positive and, in one case, C. colinum was isolated. Gross and histological lesions of positive birds were compatible with those described in other ulcerative enteritis outbreaks. These preliminary results demonstrates that C. colinum is sporadically implicated in enteric diseases of broiler chickens (14.2%. In addition, the PCR assay proved to be an useful and reliable instrument to support the diagnosis of ulcerative enteritis and to facilitate the isolation of C. colinum.

  5. Biological image construction by using Raman radiation and Pca: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Martinez E, J. C. [IPN, Unidad Profesional Interdisciplinaria de Ingenieria, Campus Guanajuato, Av. Mineral de Valenciana 200, Col. Fracc. Industrial Puerto Interior, 36275 Silao, Guanajuato (Mexico); Cordova F, T. [Universidad de Guanajuato, DIC, Departamento de Ingenieria Fisica, Loma del Bosque No. 103, Col. Lomas del Campestre, 37150 Leon, Guanajuato (Mexico); Hugo R, V., E-mail: jcmartineze@ipn.mx [Universidad de Guadalajara, Centro Universitario de Tonala, Morelos No. 180, 69584 Tonala, Jalisco (Mexico)

    2015-10-15

    Full text: In the last years, the Raman spectroscopy (Rs) technique has had some applications in the study and analysis of biological samples, due to it is able to detect concentrations or presence of certain organic and inorganic compounds of medical interest. In this work, raw data were obtained through measurements in selected points on a square regions in order to detect specific organic / inorganic compounds on biological samples. Gold nano stars samples were prepared and coated with membrane markers (CD 10+ and CD 19+) and diluted in leukemic B lymphocytes. Each data block was evaluated independently by the method of principal component analysis (Pca) in order to find representative dimensionless values (Cp) for each Raman spectrum in a specific coordinate. Each Cp was normalized in a range of 0-255 in order to generate a representative image of 8 bits of the region under study. Data acquisition was performed with Raman microscopy system Renishaw in Via in the range of 550 to 1700 cm-1 with a 785 nm laser source, with a power of 17 m W and 15 s of exposure time were used for each spectrum. In preliminary results could detect the presence of molecular markers CD 10+ and CD 19+ with gold nano stars and discrimination between both markers. The results suggest conducting studies with specific concentrations organic and inorganic materials. (Author)

  6. Systematic Search of the Nearest Stars for Exoplanetary Radio Emission: Preliminary results from LOFAR

    Science.gov (United States)

    Winterhalter, Daniel; Knapp, Mary

    2016-04-01

    Radio observations have been used as a tool to search for exoplanets since before the confirmed discovery of the first extrasolar planet. To date, neither targeted observations of known exoplanets nor surveys have produced definitive detections of exoplanetary radio emission. We present the framework for, and initial results from, a blind radio survey of the nearest star systems for exoplanetary radio emission. The very closest stars were chosen to minimize the dilution of potential radio signals by distance and thereby increase the probability of a detection. The goal of this survey is to obtain, at minimum, physically meaningful upper limits on radio emission from (or modulated by) substellar companions of the nearest stars. The target selection criteria for this survey are restricted to distance, observability for LOFAR and the VLA, and data quality metrics only. Stellar properties are not considered because preconceptions about the types of systems most likely to exhibit radio emission have not been observationally confirmed and may be incorrect. Two survey targets, GJ 411 and GJ 725A/B, have been observed with the LOFAR telescope LBA (30-75 MHz) system. A series of 4 2-hour integrations and 1 3-hour integration were made for each target of a period of approximately 2 weeks. Additional observations are underway with LOFAR as well as the VLA. Preliminary results from the first LOFAR observations are presented.

  7. Holocene evolution and sedimentation rate of Alikes Lagoon, Zakynthos island, Western Greece – preliminary results

    Directory of Open Access Journals (Sweden)

    P. Avramidis

    2009-03-01

    Full Text Available In the present study we present preliminary results of Zakynthos Alikes lagoon, which is one of the most seismically active regions of Greece. In order to estimate – interpret the Holocene evolution of the area and to reconstruct the palaeonvironmental changes, we based on the data of a 21 m sediment core. Sediment types, structure, colour, as well as contact depths and bed characteristics, were recorded in the field. Standarised sedimentological analysis were carried out, on 46 samples including grain size analysis, calculation of moment measures, and micro- and molluscan fossils of 17 selected samples. Moreover, radiocarbon age determinations have been made on individual Cardium shells from two horizons and whole – core Magnetic Susceptibility (MS measurements were taken. The interpretation of depositional environments suggests a coastal environment (restricted-shallow with reduced salinity such as a lagoon margin and in a tidal flat and/or marsh particularly. The maximum age of the study sediments is about 8500 BP. The rate of sedimentation between 8280 BP and 5590 BP was 5.3 mm/yr and between 5590 BP and modern times 1.03 mm/yr. The rate of sedimentation was higher until mid-Holocene while decrease after to 1.03 mm/yr, results which are similar to other coastal areas of western Greece.

  8. A mm-Wave Polarisation Analyser Using LEKIDs: Strategy and Preliminary Numerical Results

    Science.gov (United States)

    Tartari, A.; Belier, B.; Calvo, M.; Cammilleri, V. D.; Monfardini, A.; Piat, M.; Prêle, D.; Smoot, G. F.

    2014-08-01

    The context of this study is the development of polarisation sensitive detectors in view of future Cosmic Microwave Background experiments. Our goal is to demonstrate the possibility to make a mm-wave polarisation analyser at 150 GHz using Lumped Element Kinetic Inductance Detectors (LEKIDs). Although LEKIDs are very attractive for the relative ease of fabrication, they have an intrinsic optical response which is weakly polarisation-senstive, i.e. orthogonal linear polarisations are absorbed with comparable efficiencies (with a separation typically not exceeding few dB). To overcome this difficulty, we achieve a polarised response by means of small () superconducting Nb wire-grids. Each grid is deposited on the rear side of the 300 micron Si substrate, on which 20 nm Al resonators are patterned, so that each pixel may in principle respond as an independent polarisation analyser. Simulations show encouraging results, with a deep (-20 dB) rejection of the unwanted polarisation. Although what we present here is not yet a polarimeter, this pilot study allows us to address some relevant questions that may be crucial in view of a full polarimetric architecture development. In particular, our first prototypes will allow to assess the behaviour of small grids, the interaction between adjacent polarised pixels, and to choose the most suitable resonator geometry. What we present here are preliminary design results about devices which are currently being realised, and soon ready for optical response characterisation.

  9. Experimental Impeller Fragmentation of Iliocaval Thrombosis Under Tulip Filter Protection: Preliminary Results

    International Nuclear Information System (INIS)

    Purpose: To assess the efficacy of catheter fragmentation of massive caval thrombosis and of filter protection against procedure-related pulmonary embolism. Methods: In 10 sheep, a self-expanding tulip-shaped filter made from Wallstent mesh (diameter 25 mm) was introduced from the right jugular approach into the proximal inferior vena cava. Experimentally induced massive iliocaval thrombosis was fragmented by an impeller catheter (expanded diameter 14 mm), which was advanced coaxially through the sheath of the expanded filter. Post-procedural cavography and pulmonary angiography were performed to document the extent of caval recanalization and pulmonary embolism. Results: In all cases, impeller fragmentation cleared the inferior vena cava and the iliac veins of thrombi completely. Fragments washed downstream were trapped in the filter. In two of the first cases, parts of the clots caused pulmonary embolism before the filter was in place. Further events were avoided by a modification of the experimental setup. Except for some small peripheral perfusion defects in two cases, pulmonary angiograms did not show any incidence of pulmonary embolism. Conclusion: Our preliminary results suggest that impeller fragmentation of iliocaval thrombi under tulip filter protection is effective and does not cause significant pulmonary embolism

  10. Preliminary Results from an Investigation into Nanostructured Nuclear Radiation Detectors for Non-Proliferation Applications

    Energy Technology Data Exchange (ETDEWEB)

    ,

    2012-10-01

    In recent years, the concept of embedding composite scintillators consisting of nanosized inorganic crystals in an organic matrix has been actively pursued. Nanocomposite detectors have the potential to meet many of the homeland security, non-proliferation, and border and cargo-screening needs of the nation and, by virtue of their superior nuclear identification capability over plastic, at roughly the same cost as plastic, have the potential to replace all plastic detectors. Nanocomposites clearly have the potential of being a gamma ray detection material that would be sensitive yet less expensive and easier to produce on a large scale than growing large, whole crystals of similar sensitivity. These detectors would have a broad energy range and a sufficient energy resolution to perform isotopic identification. The material can also be fabricated on an industrial scale, further reducing cost. This investigation focused on designing and fabricating prototype core/shell and quantum dot (QD) detectors. Fourteen core/shell and four QD detectors, all with the basic consistency of a mixture of nanoparticles in a polymer matrix with different densities of nanoparticles, were prepared. Nanoparticles with sizes <10 nm were fabricated, embedded in a polystyrene matrix, and the resultant scintillators’ radiation detector properties were characterized. This work also attempted to extend the gamma energy response on both low- and high-energy regimes by demonstrating the ability to detect low-energy and high-energy gamma rays. Preliminary results of this investigation are consistent with a significant response of these materials to nuclear radiation.

  11. PRELIMINARY RESULTS OF BOWL TRAPPING BEES (HYMENOPTERA, APOIDEA IN A SOUTHERN BRAZIL FOREST FRAGMENT

    Directory of Open Access Journals (Sweden)

    Rodrigo B. Gonçalves

    2013-05-01

    Full Text Available In recent years bowl traps have gained attention as a useful method for sampling bees and are now commonly used across the world for this purpose. However, specific questions about the method itself have not yet been tested on different regions of the globe. We present the preliminary results of bowl trapping in a Semidecidual Seasonal forest fragment in southern Brazil, including the test of two different color bowls, two different habitats, and the interaction of these variables in bee species number and composition. We used blue and yellow bowls in the border and in the core trails of the forest fragment. In five sampling days between October to December bowl traps captured 745 specimens of 37 morphospecies, with Halictinae bees being the richest and most abundant group. Non parametrical statistical analyses suggested that different colors of bowl traps influenced bee richness and composition and thus, they should be used together for a more complete sampling. Different trails influenced only the composition, while the interaction with different colors did not have a significant effect. These results, as well as the higher taxonomic composition of the inventoried bees, are similar to other studies reported in the literature.

  12. Preliminary Results from the PrimEx-II experiment at Jefferson Lab

    Energy Technology Data Exchange (ETDEWEB)

    Gasparian, Ashot [NCA& T, Greensboro, NC; Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2016-06-01

    Properties of the neutral pion, as the lightest hadron in Nature, are most sensitive to the basic symmetries and their partial breaking effects in the theory of the strong interaction (QCD). In particular, the po →gg decay width is primarily defined by the spontaneous chiral symmetry breaking effect (chiral anomaly) in QCD. The next order corrections to the anomaly have been shown to be small and are known to a 1% precision level. The PrimEx Collaboration at JLab has developed and performed two Primakoff type experiments to measure the po →gg decay width with a similar precision. The published result from the PrimEx-I experiment, G(p0 →gg ) = 7.82±0.14 (stat.)±0.17 (syst.) eV, was a factor of two more precise than the average value quoted in PDG-2010 [1]. The second experiment was performed in 2010 with a goal of 1.4% total uncertainty to address the next-to-leading-order theory calculations. The preliminary results from the PrimEx-II experiment are presented and discussed in this note.

  13. [A new locking nail for proximal humerus fractures: the Telegraph nail, technique and preliminary results].

    Science.gov (United States)

    Cuny, C; Pfeffer, F; Irrazi, M; Chammas, M; Empereur, F; Berrichi, A; Metais, P; Beau, P

    2002-02-01

    We present a new nail, the telegraph nail, designed for the treatment of proximal fractures of the humerus. This nail has a new locking system providing a self-stabilization of the cancelous screws inserted in small fragments. We discuss the surgical technique and present preliminary results. The anterolateral approach and nail insertion through the medial and well vascularized part of the cuff is described for simple fractures. With the cup and ball technique, this nail can also be used for complex fractures of the proximal humerus with three or four fragments and major displacement. With this method, the nail is inserted before reduction and locked in the distal humerus before fixation of the head and tuberosities around the head once the targeting device removed. We report results for the first 64 nails inserted in our unit during the first year (1998-1999). Outcome was assessed at 11 months mean follow-up using the Constant score. Outcome was favorable, including in patients with complex fractures involving 3 or 4 separate displaced fragments. Besides providing an anatomically stable reconstruction, the telegraph nail has the advantage of allowing early mobilization of the shoulder joint. This method is a useful alternative to prosthetic reconstruction for traumatic fractures of the proximal humerus. PMID:11973536

  14. Preliminary experimental results of tungsten wire-array Z-pinches on primary test stand

    International Nuclear Information System (INIS)

    The Primary Test Stand (PTS) developed at the China Academy of Engineering Physics is a 20 TW pulsed power driver, which can deliver a ∼10 MA, 70 ns rise-time (10%–90%) current to a short-circuit load and has important applications in Z-pinch driven inertial confinement fusion and high energy density physics. Preliminary results of tungsten wire-array Z-pinch experiments on PTS are presented. The load geometries investigated include 15-mm-tall cylindrical single and nested arrays with diameter ranging from 13 mm to 30 mm, consisting of 132–300 tungsten wires with 5–10 μm in diameter. Multiple diagnostics were fielded to characterize the x-ray radiation from wire-array Z pinches. The x-ray peak power (∼50 TW) and total radiated energy (∼500 kJ) were obtained from a single 20-mm-diam array with 80-ns stagnation time. The highest x-ray peak power up to 80 TW with 2.4 ns FWHM was achieved by using a nested array with 20-mm outer diameter, and the total x-ray energy from the nested array is comparable to that of single array. Implosion velocity estimated from the time-resolved image measurement exceeds 30 cm/μs. The detailed experimental results and other findings are presented and discussed

  15. Preliminary experimental results of tungsten wire-array Z-pinches on primary test stand

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Xian-Bin; Zhou, Shao-Tong; Dan, Jia-Kun; Ren, Xiao-Dong, E-mail: amosrxd@163.com; Wang, Kun-Lun; Zhang, Si-Qun; Li, Jing; Xu, Qiang; Cai, Hong-Chun; Duan, Shu-Chao; Ouyang, Kai; Chen, Guang-Hua; Ji, Ce; Wei, Bing; Feng, Shu-Ping; Wang, Meng; Xie, Wei-Ping; Deng, Jian-Jun [Key Laboratory of Pulsed Power, Institute of Fluid Physics, China Academy of Engineering Physics, P.O. Box 919-108, Mianyang, Sichuan 621999 (China); Zhou, Xiu-Wen; Yang, Yi [Research Center of Laser Fusion, China Academy of Engineering Physics, P.O. Box 919-987, Mianyang, Sichuan 621999 (China)

    2015-07-15

    The Primary Test Stand (PTS) developed at the China Academy of Engineering Physics is a 20 TW pulsed power driver, which can deliver a ∼10 MA, 70 ns rise-time (10%–90%) current to a short-circuit load and has important applications in Z-pinch driven inertial confinement fusion and high energy density physics. Preliminary results of tungsten wire-array Z-pinch experiments on PTS are presented. The load geometries investigated include 15-mm-tall cylindrical single and nested arrays with diameter ranging from 13 mm to 30 mm, consisting of 132–300 tungsten wires with 5–10 μm in diameter. Multiple diagnostics were fielded to characterize the x-ray radiation from wire-array Z pinches. The x-ray peak power (∼50 TW) and total radiated energy (∼500 kJ) were obtained from a single 20-mm-diam array with 80-ns stagnation time. The highest x-ray peak power up to 80 TW with 2.4 ns FWHM was achieved by using a nested array with 20-mm outer diameter, and the total x-ray energy from the nested array is comparable to that of single array. Implosion velocity estimated from the time-resolved image measurement exceeds 30 cm/μs. The detailed experimental results and other findings are presented and discussed.

  16. Palliation of Postoperative Gastrointestinal Anastomotic Malignant Strictures with Flexible Covered Metallic Stents: Preliminary Results

    International Nuclear Information System (INIS)

    Purpose: To evaluate the efficacy of the placement of covered metallic stents for palliation of gastrointestinal anastomotic strictures secondary to recurrent gastric cancer.Methods: Under fluoroscopic guidance, placement of one or two self-expandable covered metallic stents was attempted perorally in 11 patents (aged 48-76 years) with anastomotic stenoses due to recurrent gastric malignancies. The strictures involved both the afferent and efferent loops in three patients. All patients had poor peroral food intake with severe nausea and vomiting after ingestion. The technical and clinical success was evaluated.Results: Placement of the covered stent was technically successful in 13 of 15 (87%) attempts in ten patients. After the procedure, 9 of 11 (82%) patients overall were able to ingest at least a liquid diet and had markedly decreased incidence of vomiting. During the follow-up of 2-31 weeks (mean 8.5 weeks) there were no major complications.Conclusion: These preliminary results suggest that flexible, covered stents may provide effective palliation of malignant anastomotic stricture secondary to recurrent gastric cancer

  17. Low-dose helical chest CT in asbestos exposed workers in the Veneto Region: preliminary results

    International Nuclear Information System (INIS)

    Purpose. To evaluate the preliminary results of low-dose helical chest CT in a group of individuals with an occupational exposure to asbestos. Materials and methods. Between October 2000 and May 2004, 1512 asymptomatic subjects, selected by Occupational Health physicians of the Veneto Region among those with a significant exposure to asbestos, underwent low-dose helical chest CT without contrast media administration. According to their features, all pulmonary nodules identified underwent pathology, further CT evaluation or follow-up with low-dose CT. Results. Apart tram benign pleural findings (in 40% of subjects), 590 pulmonary nodules were identified. Eleven nodules underwent pathologic examination, which detected 5 malignant lesions, and 51 were evaluated with other CT techniques, in all cases demonstrating benign features. In followup low-dose CT scans, performed in the remaining 528 nodules, a minimal increase in size occurred in 4 cases only. Conclusions. Screening for clinically relevant pulmonary lesions in asymptomatic people with occupational exposure to asbestos may be useful if rigorous enrolment criteria are adopted. The management of abnormal findings is cost-effective if it is based on the morphological features of each finding

  18. Simplified benchmark based on 2670 ISTC WWER post-irradiation examinations - specification and preliminary results

    International Nuclear Information System (INIS)

    Experimental validation of depletion computer codes is an ongoing need in spent fuel management. In WWER application area the lack of well-documented experimental data concerning depleted fuel is serious, being an obstacle to introduce new effective technologies and approaches in spent fuel management, e.g. burnup credit (BUC). In 2004, the final report of ISTC 2670 project on post-irradiation examinations (PIE) of eight samples from Novovoronezh-4 NPP (specimens taken from one assembly covering burnup range from 22 to 45 MWd/kgU) was released and published. The 2670 WWER-440 post-irradiation is the first publicly available measurement providing also fission product concentrations for the 'BUC set' of isotopes. Although the documentation of the experiment was quite comprehensive, still there were missing some important data needed for a precise depletion simulation. Therefore in 2006, NRI in collaboration with RIAR Dimitrovgrad, where the measurements were carried out, gathered the missing data and prepared a well-specified simplified benchmark, based on this measurement. Its specification as well as results of preliminary calculations using several depletion codes are presented in this paper. Final evaluation of the results calculated by all benchmark participants is expected for presentation in 2008 (Authors)

  19. Biological image construction by using Raman radiation and Pca: preliminary results

    International Nuclear Information System (INIS)

    Full text: In the last years, the Raman spectroscopy (Rs) technique has had some applications in the study and analysis of biological samples, due to it is able to detect concentrations or presence of certain organic and inorganic compounds of medical interest. In this work, raw data were obtained through measurements in selected points on a square regions in order to detect specific organic / inorganic compounds on biological samples. Gold nano stars samples were prepared and coated with membrane markers (CD 10+ and CD 19+) and diluted in leukemic B lymphocytes. Each data block was evaluated independently by the method of principal component analysis (Pca) in order to find representative dimensionless values (Cp) for each Raman spectrum in a specific coordinate. Each Cp was normalized in a range of 0-255 in order to generate a representative image of 8 bits of the region under study. Data acquisition was performed with Raman microscopy system Renishaw in Via in the range of 550 to 1700 cm-1 with a 785 nm laser source, with a power of 17 m W and 15 s of exposure time were used for each spectrum. In preliminary results could detect the presence of molecular markers CD 10+ and CD 19+ with gold nano stars and discrimination between both markers. The results suggest conducting studies with specific concentrations organic and inorganic materials. (Author)

  20. A Morphing Technique Applied to Lung Motions in Radiotherapy: Preliminary Results

    Directory of Open Access Journals (Sweden)

    R. Laurent

    2010-01-01

    Full Text Available Organ motion leads to dosimetric uncertainties during a patient’s treatment. Much work has been done to quantify the dosimetric effects of lung movement during radiation treatment. There is a particular need for a good description and prediction of organ motion. To describe lung motion more precisely, we have examined the possibility of using a computer technique: a morphing algorithm. Morphing is an iterative method which consists of blending one image into another image. To evaluate the use of morphing, Four Dimensions Computed Tomography (4DCT acquisition of a patient was performed. The lungs were automatically segmented for different phases, and morphing was performed using the end-inspiration and the end-expiration phase scans only. Intermediate morphing files were compared with 4DCT intermediate images. The results showed good agreement between morphing images and 4DCT images: fewer than 2 % of the 512 by 256 voxels were wrongly classified as belonging/not belonging to a lung section. This paper presents preliminary results, and our morphing algorithm needs improvement. We can infer that morphing offers considerable advantages in terms of radiation protection of the patient during the diagnosis phase, handling of artifacts, definition of organ contours and description of organ motion.

  1. Upper Pleistocene - Holocene activity of the Carrascoy Fault (Murcia, SE Spain): preliminary results from paleoseismological research.

    Science.gov (United States)

    Martin-Banda, Raquel; Garcia-Mayordomo, Julian; Insua-Arevalo, Juan M.; Salazar, Angel; Rodriguez-Escudero, Emilio; Alvarez-Gomez, Jose A.; Martinez-Diaz, Jose J.; Herrero, Maria J.; Medialdea, Alicia

    2014-05-01

    The Carrascoy Fault is located in the Internal Zones of the Betic Cordillera (Southern Spain). In particular, the Carrascoy Fault is one of the major faults forming the Eastern Betic Shear Zone, the main structure accommodating the convergence between Nubian and Eurasian plates in the westernmost Mediterranean. So far, the Carrascoy Fault has been defined as a left-lateral strike-slip fault. It extends for at least 31 km in a NE-SW trend from the village of Zeneta (Murcia) at its northeastern tip, to the Cañaricos village, controlling the northern edge of the Carrascoy Range and its linkage to the Guadalentin Depression towards the southwest. This is an area of moderate seismic activity, but densely populated, the capital of the region, Murcia, being settled very close to the fault. Hence, the knowledge of the structure and kinematics of the Carrascoy Fault is essential for assessing reliably the seismic hazard of the region. We present a detailed-scale geological and geomorphological map along the fault zone created from a LIDAR DEM combined with fieldwork, and geological and geophysical information. Furthermore, a number of trenches have been dug across the fault at different locations providing insights in the fault most recent activity as well as paleoseismic data. Preliminary results suggest that the Cararscoy Fault has recently changed its kinematic showing a near pure reverse motion. According to this, the fault can be divided into two distinct segments, the eastern one: Zeneta - Fuensanta, and the western one: Fuensanta - Cañaricos, each one having its own characteristic style and geodynamics. Some new active strands of the fault locate at the foot of the very first relief towards the North of the older strand, forming the current southern border of the Guadalentin Depression. These new faults show an increasingly reverse component westwards, so that the Fuensanta - Cañaricos segment is constituted by thrusts, which are blind at its western end

  2. Epigenetic perturbations in the pathogenesis of mustard toxicity; hypothesis and preliminary results

    International Nuclear Information System (INIS)

    The pathogenesis of sulfur mustard (SM) toxicity is not fully understood, although it is related to reactive oxygen and nitrogen species, oxidative stress, DNA damage, poly (ADP-ribose) polymerase activation within the affected cell. We, therefore, made an attempt whether epigenetic aberrations may contribute to pathogenesis of SM poisoning in rats' lung. A total of 40 male SD rats were divided into 4 groups. Group 1 served as control and given 2 ml saline, three groups received single dose of mechlorethamine (MEC) (3.5 mg/kg subcutaneously) with the same time intervals. Group 2 received MEC only; group 3 received histone deacetylase (HDAC) inhibitor (Trichostatine A) (1 mg/kg) and group 4 received DNA methyl transferase (DNMT) inhibitor (5-Azacytidine) (0.02 mg/kg), intraperitoneally. MEC injection resulted in severe lung toxicity with strong interstitial and alveolar edema, hemorrhage, emphysematous changes as well as mild inflammatory cell infiltration and septal thickening. In group 3, the HDAC inhibitor significantly reduced interstitial and alveolar edema, hemorrhage and inflammatory cell infiltration. On the other hand, we have observed severe lung damage by using DNMT inhibitor (group 4). In HDAC inhibitor group, the results were close to sham group. In DNMT inhibitor group, however, lungs were worse than MEC group results. These preliminary results revealed that, SM itself and/or its intracellular metabolites may perturb the epigenetic environment of the affected cell in lung tissue. Hypothetically, MEC may cause HDAC induction leading to a variety of gene silencing. Trichostatine A can reduce the active enzyme level and can reactivate the already silenced genes. Further studies are needed to clarify the involvement of epigenetic perturbations in the pathogenesis of mustard toxicity.(author)

  3. Measurement of single kidney contrast media clearance by multiphasic spiral computed tomography: preliminary results

    International Nuclear Information System (INIS)

    Objective. We present preliminary results of a new method (hereinafter called 'CT-clearance') to measure single kidney contrast media clearance by performing multiphasic helical CT of the kidneys. CT-clearance was calculated according to an extension of the Patlak-Plot. In contrast to prior investigators, who repeatedly measured a single slice, this method makes it possible to calculate single kidney clearance from at least three spiral CTs, utilizing the whole kidney volume. Methods. Spiral CT of the kidneys was performed unenhanced and about 30 and 100 s after administration of about 120 ml iopromide. Sum-density of the whole kidneys and aortic density was calculated from this data. Using this data, renal clearance of contrast media was calculated by CT-clearance in 29 patients. As reference, Serum-clearance was calculated in 24 patients by application of a modified one-exponential slope model. Information on the relative kidney function was gained by renal scintigraphy with Tc99m-MAG-3 or Tc99m-DMSA in 29 patients. Results. Linear regression analysis revealed a correlation coefficient of CT-clearance with Serum-clearance of r=0.78 with Cl (CT) [ml/min]=22.2+1.03 * Cl (serum), n=24. Linear regression of the relative kidney function (rkf) of the right kidney calculated by CT-clearance compared to scintigraphy results provided a correlation coefficient r=0.89 with rkf(CT)[%]=18.6+0.58 * rkf(scintigraphy), n=29. Conclusion. The obtained results of contrast media clearance measured by CT-clearance are in the physiological range of the parameter. Future studies should be performed to improve the methodology with the aim of higher accuracy. More specifically, better determination of the aortic density curve might improve the accuracy

  4. Preliminary Results from Hydrologic Monitoring of Mill and Farm Ponds in Burgundy, France

    Science.gov (United States)

    Strano, S.; Misner, T.; Rosenmeier, M.; Bain, D.; Straffin, E.

    2008-12-01

    This paper presents the preliminary results from a year-long intensive hydrologic monitoring study completed in three small freshwater reservoirs (mill and farm ponds) within the Arroux River Valley, Burgundy, France. The study includes assessment of the seasonal variability of reservoir water levels and chemistry and hydrologic modeling of the watersheds. Several shallow monitoring wells were installed around each reservoir, and groundwater and surface water inflows and outflows were sampled monthly. All water samples were analyzed for major cations (Na, Mg, K, Ca) and anions (F, Cl, SO4, NO2, NO3) as well as stable isotopic composition. Monthly well and continuous reservoir water levels were also recorded. The water monitoring data was combined with nearby weather station data (available from 1955 to present) to model the hydroclimatology and hydrogeochemistry of the reservoirs. This modern data will be used to interpret (i.e., calibrate and validate) geochemical records from sediment cores collected from the reservoirs, which date to at least 1200 A.D. Modern watershed and sediment core data will also be compared with known local land use histories to examine the relative influence of climate and human activity on watershed dynamics. This work thus has broad implications for many watershed studies where historical records of land use and climate change are not available but instead are inferred from geological or ecological evidence.

  5. Preliminary Paleomagnetic Results From Tertiary Rocks of Sedimentary Basins in Northern Vietnam and Tectonic Implications

    Science.gov (United States)

    Zhao, X.; Liu, Z.; Le, K.; Zhao, Y.; Hoang, V.; Phan, D.

    2013-12-01

    The South China Sea (SCS) is a classical representative of western Pacific marginal seas and contains records of Cenozoic tectonic events of SE Asia. The SCS has been at the center stage of many first-order tectonic and paleoclimatic events since the Mesozoic. One clear way to evaluate the relationship between tectonic uplift and climate is to study the resulting changes in marginal sea strata. To this end, we will conduct an integrated paleomagnetic and stratigraphic investigation on Tertiary strata from Phu Tho and Yen Bai provinces, northern Vietnam to help understand the causal linkages among geological and tectonic events and their consequences related to the SCS evolution. We will collect paleomagnetic samples at sections where the most continuous, complete, and best preserved Eocene-Miocene successions. Standard paleomagnetic field tests, such as the fold, reversal, and conglomerate tests will be used to determine the relative age of the magnetization. In addition to detailed thermal and alternating field demagnetization and analysis, selected samples will also be subjected to several rock magnetic analyses to identify magnetic carriers in the rocks. In particular, the hysteresis parameters Jrs/Js and Hcr /Hc ratios will enable us to apply techniques for detecting low-temperature remagnetization of sedimentary rocks. Preliminary finding of this ongoing project will be presented.

  6. The Geoengineering Model Intercomparison Project Phase 6 (GeoMIP6). Simulation Design and Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Kravitz, Benjamin S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Robock, Alan [Rutgers Univ., New Brunswick, NJ (United States); Tilmes, S. [National Center for Atmospheric Research, Boulder, CO (United States); Boucher, Olivier [Laboratoire de Meteorologie Dynamique, Paris (France); English, J. [NOAA Earth System Research Lab. and Univ. of Colorado, Boulder, CO (United States); Irvine, Peter [Inst. of Advanced Sustainability Studies, Potsdam (Germany); Jones, Andrew [Met Office Hadley Centre, Exeter (United Kingdom); Lawrence, M. G. [Inst. of Advanced Sustainability Studies, Potsdam (Germany); Maccracken, Michael C. [Climate Inst., Washington, DC (United States); Muri, Helene O. [Univ. of Oslo (Norway); Moore, John [Beijing Normal Univ., Beijing (China); Niemeier, Ulrike [Max Planck Inst. for Meterology, Hamburg (Germany); Phipps, Steven [Univ. of New South Wales, Sydney, NSW (Australia); Sillmann, Jana [Center for International Climate and Environmental Research, Oslo (Norway); Storelvmo, Trude [Yale Univ., New Haven, CT (United States); Wang, Hailong [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Watanabe, Shingo [Japan Agency for Marine-Earth Science and Technology, Yokohama (Japan)

    2015-10-27

    We present a suite of new climate model experiment designs for the Geoengineering Model Intercomparison Project (GeoMIP). This set of experiments, named GeoMIP6 (to be consistent with the Coupled Model Intercomparison Project Phase 6), builds on the previous GeoMIP project simulations, and has been expanded to address several further important topics, including key uncertainties in extreme events, the use of geoengineering as part of a portfolio of responses to climate change, and the relatively new idea of cirrus cloud thinning to allow more longwave radiation to escape to space. We discuss experiment designs, as well as the rationale for those designs, showing preliminary results from individual models when available. We also introduce a new feature, called the GeoMIP Testbed, which provides a platform for simulations that will be performed with a few models and subsequently assessed to determine whether the proposed experiment designs will be adopted as core (Tier 1) GeoMIP experiments. This is meant to encourage various stakeholders to propose new targeted experiments that address their key open science questions, with the goal of making GeoMIP more relevant to a broader set of communities.

  7. Characterization of sediments from Voglajna and Savinja rivers – preliminary results

    Directory of Open Access Journals (Sweden)

    Stanislav Frančišković-Bilinski

    2002-12-01

    Full Text Available Preliminary mineralogical, geochemical and Mössbauer studies of six surface sediments (fraction <63 μm from Voglajna and Savinja rivers (Slovenia are reported for the first time. The location was chosen because of two reasons. One was possible pollution due to industry in Celje. Another was presumed high concentration of iron (later found 2.8 – 5.6 %, easily studied by Mössbauer spectroscopy. XRD data showed that quartz is present in all samples. Other minerals are different in different locations. Iron can be present in Fe-chlorite and in montmorillonite, found by XRD as trace minerals. Microelements were determined by ICP-MS method. Sediment of Voglajna near Štore contain the highest concentrations of S, P, Cr, Ni, Pb, Cu, Mo, Sb, W and Hg. Sediment of Savinja at Tremerje contain the highest concentrations of Zn, Cd, Ag and Au. These results indicate industrial pollution around Celje. Further characterization of Fe (II and Fe (III was performed by 57Fe Mössbauer spectroscopy at room temperature. Spectra were fitted with two and in one case with three doublets. In addition to the presence of two doublets, two magnetic sextets are present in the sediment of Voglajna at Štore, suggesting minor quantity of Fe3O4. The Fe (III / Fe (II ratio decreases downstream the Voglajna river. The work is in progress on additional sampling stations.

  8. Observation of seismicity based on DOMERAPI and BMKG seismic networks: A preliminary result from DOMERAPI project

    Science.gov (United States)

    Ramdhan, Mohamad; Nugraha, Andri Dian; Widiyantoro, Sri; Kristyawan, Said; Sembiring, Andry Syaly; Mtaxian, Jean-Philippe

    2016-05-01

    DOMERAPI project has involved earth scientists from Indonesia and France to conduct comprehensively a study of the internal structure of Mt. Merapi and its vicinity based on seismic tomographic imaging. The DOMERAPI seismic network was running from October 2013 to April 2015 consisting of 53 broad-band seismometers, covering Mt. Merapi and Mt. Merbabu, and some geological features such as Opak and Dengkeng faults. Earthquake hypocenter determination conducted in this study is an important step before seismic tomographic imaging. The earthquake events were identified and picked manually and carefully. The majority of earthquakes occured outside the DOMERAPI network. The ray paths of seismic waves from these earthquakes passed through the deep part of the study area around Merapi. The joint data of BMKG and DOMERAPI networks can minimize the azimuthal gap, which is often used to obtain an indication of the reliability of the epicentral solution. Our preliminary results show 279 events from October 2013 to mid August 2014. For future work, we will incorporate the BPPTKG (Center for Research and Technology Development of Geological Disaster) data catalogue in order to enrich seismic ray paths. The combined data catalogues will provide information as input for further advanced studies and volcano hazards mitigation.

  9. Preliminary results of the analysis of the administered activities in diagnostic studies of nuclear medicine

    International Nuclear Information System (INIS)

    The worldwide use of Nuclear Medicine diagnostic procedures and the tendency to its increment, infers an important exposure of the population to ionising radiation; it has motivated that the IAEA in the International Basic Safety Standards (BSS), emits recommendations for the establishment of guidance levels of activities administered to the patients in diagnostic procedures. Taking into account the above-mentioned and that in Cuba there exist 20 departments of Nuclear Medicine that in the majority possess equipment with more than 20 years of operation, which influences directly the medical exposure. A survey was designed and applied in 10 of these departments. The survey evaluates the compliance with the BSS requirements, and specifically, the activities administered to the patients in Nuclear Medicine diagnostic procedures are analysed. In the present work the obtained preliminary results of the statistical analysis carried out on the activity values used in Nuclear Medicine departments are presented, and comparisons made for a proposal of guidance levels for the national practice, which is compared with those recommended internationally. (author)

  10. Diagnosis of breast cancer using elastic-scattering spectroscopy: preliminary clinical results

    Science.gov (United States)

    Bigio, Irving J.; Brown, Stephen G.; Briggs, Gavin M.; Kelley, Christine; Lakhani, Sunil; Pickard, David; Ripley, Paul M.; Rose, Ian; Saunders, Christobel

    2000-04-01

    We report on the first stages of a clinical study designed to test elastic-scattering spectroscopy, medicated by fiberoptic probes, for three specific clinical applications in breast-tissue diagnosis: (1) a transdermal-needle (interstitial) measurement for instant diagnosis with minimal invasiveness similar to fine-needle aspiration but with sensitivity to a larger tissue volume, (2) a hand-held diagnostic probe for use in assessing tumor/resection margins during open surgery, and (3) use of the same probe for real-time assessment of the `sentinel' node during surgery to determine the presence or absence of tumor (metastatic). Preliminary results from in vivo measurements on 31 women are encouraging. Optical spectra were measured on 72 histology sites in breast tissue, and 54 histology sites in sentinel nodes. Two different artificial intelligence methods of spectral classification were studied. Artificial neural networks yielded sensitivities of 69% and 58%, and specificities of 85% and 93%, for breast tissue and sentinel nodes, respectively. Hierarchical cluster analysis yielded sensitivities of 67% and 91%, and specificities of 79% and 77%, for breast tissue and sentinel nodes, respectively. These values are expected to improve as the data sets continue to grow and more sophisticated data preprocessing is employed. The study will enroll up to 400 patients over the next two years.

  11. Preliminary result of earthquake hypocenter determination using hypoellipse around western Java region

    Science.gov (United States)

    Supendi, Pepen; Nugraha, Andri Dian

    2016-05-01

    West Java region is located in high seismicity and active tectonic setting region influenced by subducting Indo-Australian plate beneath Eurasia plate. There are several on land active faults namely Cimandiri fault, Lembang fault, and Baribis fault in the region. MCGA earthquake data catalog from 2009 to 2014 shows the earthquakes were located not only around active faults but also relatively far away from the active faults in West Java region. In this study, we determined the earthquake location through re-picking of P-and S-wave arrival times recording by MCGA network. Earthquake location was determined by using Hypoellipse code that employs a single event determination method. We then relocated the events using hypocenter double-difference method. We also have been conducting focal mechanism analysis to estimate the type of fault slip. Our preliminary results show generally the epicenter location were distributed around the on land active fault which have the focus depth less than 30 km. For ongoing and future works, we have been determining focal mechanism of selected event related to on land active fault for this region..

  12. Preliminary results from simulations of temperature oscillations in Stirling engine regenerator matrices

    International Nuclear Information System (INIS)

    The objective of this study has been to create a Stirling engine model for studying the effects of regenerator matrix temperature oscillations on Stirling engine performance. A one-dimensional model with axial discretisation of engine components has been formulated using the control volume method. The model contains a system of ordinary differential equations (ODEs) derived from mass and energy balances for gas filled control volumes and energy balances for regenerator matrix control masses. Interpolation methods with filtering properties are used for state variables at control volume interfaces to reduce numerical diffusion and/or non-physical oscillations. Loss mechanisms are included directly in the governing equations as terms in the mass and energy balances. Steady state periodic solutions that satisfy cyclic boundary conditions and integral conditions are calculated using a custom built shooting method. It has been found possible to accurately solve the stiff ODE system that describes the coupled thermodynamics of the gas and the regenerator matrix and to reliably find periodic steady state solutions to the model. Preliminary results indicate that the regenerator matrix temperature oscillations do have significant impact on the regenerator loss, the cycle power output, and the cycle efficiency and thus deserve further study

  13. Preliminary results from simulations of temperature oscillations in Stirling engine regenerator matrices

    Energy Technology Data Exchange (ETDEWEB)

    Andersen, Stig Kildegaard [Department of Mechanical Engineering, Technical University of Denmark, DK-2800 Lyngby (Denmark)]. E-mail: ska@mek.dtu.dk; Carlsen, Henrik [Department of Mechanical Engineering, Technical University of Denmark, DK-2800 Lyngby (Denmark); Thomsen, Per Grove [Informatics and Mathematical Modelling, Technical University of Denmark, DK-2800 Lyngby (Denmark)

    2006-08-15

    The objective of this study has been to create a Stirling engine model for studying the effects of regenerator matrix temperature oscillations on Stirling engine performance. A one-dimensional model with axial discretisation of engine components has been formulated using the control volume method. The model contains a system of ordinary differential equations (ODEs) derived from mass and energy balances for gas filled control volumes and energy balances for regenerator matrix control masses. Interpolation methods with filtering properties are used for state variables at control volume interfaces to reduce numerical diffusion and/or non-physical oscillations. Loss mechanisms are included directly in the governing equations as terms in the mass and energy balances. Steady state periodic solutions that satisfy cyclic boundary conditions and integral conditions are calculated using a custom built shooting method. It has been found possible to accurately solve the stiff ODE system that describes the coupled thermodynamics of the gas and the regenerator matrix and to reliably find periodic steady state solutions to the model. Preliminary results indicate that the regenerator matrix temperature oscillations do have significant impact on the regenerator loss, the cycle power output, and the cycle efficiency and thus deserve further study.

  14. Gamma radiation measurement in select sand samples from Camburi beach - Vitoria, Espirito Santo, Brazil: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Barros, Livia F.; Pecequilo, Brigitte R.S.; Aquino, Reginaldo R., E-mail: lfbarros@ipen.b, E-mail: brigitte@ipen.b, E-mail: raquino@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    The variation of natural radioactivity along the surface of the beach sands of Camburi, located in Vitoria, capital of Espirito Santo, southeastern Brazil, was determined from the contents of {sup 226}Ra, {sup 232}Th and {sup 40}K. Eleven collecting points was selected along all the 6 km extension of the Camburi beach. Sand samples collected from all established points on January 2011 were dried and sealed in standard 100 mL polyethylene flasks and measured by high resolution gamma spectrometry after a 4 weeks ingrowth period, in order to allow the secular equilibrium in the {sup 238}U and {sup 232}Th series. The {sup 226}Ra concentration was determined from the weighted average concentrations of {sup 214}Pb and {sup 214}Bi. The {sup 232}Th concentration was determined from the weighted average concentrations of {sup 228}Ac, {sup 212}Pb and {sup 212}Bi and the {sup 40}K from its single gamma transition. Preliminary results show activity concentrations varying from 5 Bq.kg{sup -1} to {sup 222} Bq.kg{sup -1} for {sup 226}Ra and from 14 Bq.kg{sup -1} to 1074 Bq.kg{sup -'}1 for {sup 232}Th, both with the highest values for Camburi South and Central. For {sup 40}K, the activity concentrations ranged from 14 Bq.kg{sup -1} to 179 Bq.kg{sup -1} and the highest values were obtained for Camburi South. (author)

  15. Cernavoda NPP impact study on terrestrial and aquatic biota. Preliminary results

    International Nuclear Information System (INIS)

    Recently, the awareness of the vulnerability of the environment has increased and the need to protect it against industrial pollutants has been recognized. The concept of sustainable development, requires new and developing international policies for environmental protection. See 'Protection of the environment from the effects of ionizing radiation' IAEA-TECDOC-1091, International Atomic Energy Agency, Vienna. As it is recommended in 'Cernavoda Unit No. 2 NPP Environmental Impact Assessment CES-03702-IAD-006', it is Cernavoda NPP responsibility to conduct an Ecological Risk Assessment study, mainly to assess the impact of nuclear power plant operation on terrestrial and aquatic biota. Long records from normal operation of Cernavoda Unit 1, wind pattern, meteorological conditions, and source terms data were used to evaluate areas of interest for environmental impact, conducting to a circle of 20 km radius around mentioned nuclear objective. The screening campaign established tritium level (because Cernavoda NPP is a CANDU type reactor, and tritium is the most important radioisotope evacuated in the environment) in air, water, soil and vegetation, focusing the interest area on particular ecosystem. Using these primary data it was evaluated which are the monitored ecological receptors and which are the measurement endpoints.This paper presents the Ecological Risk Assessment at Cernavoda NPP technical requirements, and the preliminary results of evaluating criteria for representative ecosystem components at Cernavoda NPP. (authors)

  16. The DEEP-South: Preliminary Photometric Results from the KMTNet-CTIO

    Science.gov (United States)

    Kim, Myung-Jin; Moon, Hong-Kyu; Choi, Young-Jun; Yim, Hong-Suh; Bae, Youngho; Roh, Dong-Goo; the DEEP-South Team

    2015-08-01

    The DEep Ecliptic Patrol of the Southern sky (DEEP-South) will not only conduct characterization of targeted asteroids and blind survey at the sweet spots, but also utilize data mining of small Solar System bodies in the whole KMTNet archive. As round-the-clock observation with the KMTNet is optimized for spin characterization of tumbling and slow-rotating bodies as it facilitates debiasing previously reported lightcurve observations. It is also most suitable for detection and rapid follow-up of Atens and Atiras, the “difficult objects” that are being discovered at lower solar elongations.For the sake of efficiency, we implemented an observation scheduler, SMART (Scheduler for Measuring Asteroids RoTation), designed to conduct follow-up observations in a timely manner. It automatically updates catalogs, generates ephemerides, checks priorities, prepares target lists, and sends a suite of scripts to site operators. We also developed photometric analysis software called ASAP (Asteroid Spin Analysis Package) that aids to find a set of appropriate comparison stars in an image, to derive spin parameters and reconstruct lightcurve simultaneously in a semi-automatic manner. In this presentation, we will show our preliminary results of time series analyses of a number of km-sized Potentially Hazardous Asteroids (PHAs), 5189 (1990 UQ), 12923 (1999 GK4), 53426 (1999 SL5), 136614 (1993 VA6), 385186 (1994 AW1), and 2000 OH from test runs in February and March 2015 at the KMTNet-CTIO.

  17. REGAT: The Algerian Permanent GPS Network. Strategy, configuration and preliminary results.

    Science.gov (United States)

    Yelles-Chaouche, Abdelkarim; Lammali, Kamel; Bellik, Amar; Mahsas, Abdelhakim; Bacha, Wahab; Bougrine, Amina

    2013-04-01

    Northern Algeria, located along the Eurasiatic-African boundary plate is characterised by a moderate to strong seismic activity. During History, some violent earthquakes occurred mainly in the Atlas region, particularly in the Tellian area, leading sometimes to destruction of major cities of Algeria (Algiers, 1716; Oran, 1790; Blida, 1825; El Asnam, 1980; Constantine, 1985; Boumerdes, 2003…). In order to improve the knowledge of the deformation pattern of the Atlasic region, and more globally of the African (Nubia)-Eurasia plate boundary along the Algerian margin, the Research Center of Astronomy, Astrophysics and Geophysics (CRAAG) started since six year to implement a permanent GPS network. The REGAT (REseau Géodésique de l'Atlas), consists on a set of 56 continuous GPS stations deployed in the Atlas region, from the coastal area to the Sahara Platform with one station at Tamanrasset, in the southern part of the country. The deployment strategy consisted in two phases: - The first one began on 2004 with 14 stations installed - The second phase, which started in 2011concerns a set of 42 stations. We present here the procedure used to collect, store and process the GPS data from the REGAT network and present the preliminary results of the stations which observed more than three years. Keywords: Earthquake, GPS, Networks, REGAT.

  18. The Geographic Climate Information System Project (GEOCLIMA): Overview and preliminary results

    Science.gov (United States)

    Feidas, H.; Zanis, P.; Melas, D.; Vaitis, M.; Anadranistakis, E.; Symeonidis, P.; Pantelopoulos, S.

    2012-04-01

    The project GEOCLIMA aims at developing an integrated Geographic Information System (GIS) allowing the user to manage, analyze and visualize the information which is directly or indirectly related to climate and its future projections in Greece. The main components of the project are: a) collection and homogenization of climate and environmental related information, b) estimation of future climate change based on existing regional climate model (RCM) simulations as well as a supplementary high resolution (10 km x 10 km) simulation over the period 1961-2100 using RegCM3, c) compilation of an integrated uniform geographic database, and d) mapping of climate data, creation of digital thematic maps, and development of the integrated web GIS application. This paper provides an overview of the ongoing research efforts and preliminary results of the project. First, the trends in the annual and seasonal time series of precipitation and air temperature observations for all available stations in Greece are assessed. Then the set-up of the high resolution RCM simulation (10 km x 10 km) is discussed with respect to the selected convective scheme. Finally, the relationship of climatic variables with geophysical features over Greece such as altitude, location, distance from the sea, slope, aspect, distance from climatic barriers, land cover etc) is investigated, to support climate mapping. The research has been co-financed by the European Union (European Regional Development Fund) and Greek national funds through the Operational Program "Competitiveness and Entrepreneurship" of the National Strategic Reference Framework (NSRF) - Research Funding Program COOPERATION 2009.

  19. Extremity exposure in nuclear medicine: Preliminary results of a European study

    International Nuclear Information System (INIS)

    The Work Package 4 of the ORAMED project, a collaborative project (2008-11) supported by the European Commission within its seventh Framework Programme, is concerned with the optimisation of the extremity dosimetry of medical staff in nuclear medicine. To evaluate the extremity doses and dose distributions across the hands of medical staff working in nuclear medicine departments, an extensive measurement programme has been started in 32 nuclear medicine departments in Europe. This was done using a standard protocol recording all relevant information for radiation exposure, i.e. radiation protection devices and tools. This study shows the preliminary results obtained for this measurement campaign. For diagnostic purposes, the two most-used radionuclides were considered: 99mTc) and 18F. For therapeutic treatments, Zevalin R and DOTATOC (both labelled with 90Y) were chosen. Large variations of doses were observed across the hands depending on different parameters. Furthermore, this study highlights the importance of the positioning of the extremity dosemeter for a correct estimate of the maximum skin doses. (authors)

  20. The Geoengineering Model Intercomparison Project Phase 6 (GeoMIP6: simulation design and preliminary results

    Directory of Open Access Journals (Sweden)

    B. Kravitz

    2015-10-01

    Full Text Available We present a suite of new climate model experiment designs for the Geoengineering Model Intercomparison Project (GeoMIP. This set of experiments, named GeoMIP6 (to be consistent with the Coupled Model Intercomparison Project Phase 6, builds on the previous GeoMIP project simulations, and has been expanded to address several further important topics, including key uncertainties in extreme events, the use of geoengineering as part of a portfolio of responses to climate change, and the relatively new idea of cirrus cloud thinning to allow more longwave radiation to escape to space. We discuss experiment designs, as well as the rationale for those designs, showing preliminary results from individual models when available. We also introduce a new feature, called the GeoMIP Testbed, which provides a platform for simulations that will be performed with a few models and subsequently assessed to determine whether the proposed experiment designs will be adopted as core (Tier 1 GeoMIP experiments. This is meant to encourage various stakeholders to propose new targeted experiments that address their key open science questions, with the goal of making GeoMIP more relevant to a broader set of communities.

  1. 18F - fluorodeoxyglucose (FDG) and broncho-pulmonary cancer. Preliminary results

    International Nuclear Information System (INIS)

    The metabolic imaging allowed by emission positron tomography (EPT) represents a new approach in the cancer diagnosis. The augmentation of glycoprotein metabolism in malignant lesions can be evidenced by FDG. The broncho-pulmonary cancer (BPC) poses clinical problems of tissue characterization which are not solved optimally by radiological imaging, so that the new technique presents a major interest. The authors report the first data obtained in France with a positron chamber in 12 patients studied since June 1996, namely 10 cases of pulmonary nodules and two of mediastinal ganglionic extension of BPC. Cross sections from skull to pelvis were achieved 45 minutes after the IV injection of 37 MBq of FDG per 10 kg of weight. The anatomical-pathological examination was systematic and the agreement with EPT was good in 10 cases of 12 (9 positive trues and 1 negative true), in addition, new sites were evidenced, 3 times of 12. They were overlooked by the radiological technique and thus, susceptible of modifying the treatment. These preliminary results are coherent with those reported in the international literature. They incited starting a prospective large-scale study of measuring the diagnosis performances of FDG in EPT in determining the malignity of solitary nodules and mediastinal extension of primary tumors

  2. Elemental composition of size-fractionated urban aerosol collected in Florence, Italy; preliminary results

    Science.gov (United States)

    Del Carmine, P.; Lucarelli, F.; Mandò, P. A.; Valerio, M.; Prati, P.; Zucchiatti, A.

    1999-04-01

    An extensive investigation is in progress aiming at the characterisation of the air particulate composition in Florence. We present here the preliminary results concerning the analysis of size-fractionated aerosol samples taken by two-stage streaker samplers in two sites characterised by different urban settings (one in a heavy traffic area, one in a green area). The sampling period (21 January-22 February) includes two days during which the Municipality of Florence has banned the circulation of non-catalytic cars, due to the increase of NO 2 above the "recommended safety values". Hourly concentrations of 20 elements from Na to Pb were determined using the external beam PIXE facility of the I.N.F.N. Van de Graaff accelerator at the Physics Department of the Florence University. Factor analysis on the data set confirms that traffic is the main source of atmospheric pollution in Florence. The ban of non-catalytic cars seems to have produced no effect on the concentration of detected elements (in particular Pb and Br).

  3. Two-dimensional computer simulation of hypervelocity impact cratering: some preliminary results for Meteor Crater, Arizona

    International Nuclear Information System (INIS)

    A computational approach used for subsurface explosion cratering was extended to hypervelocity impact cratering. Meteor (Barringer) Crater, Arizona, was selected for the first computer simulation because it is one of the most thoroughly studied craters. It is also an excellent example of a simple, bowl-shaped crater and is one of the youngest terrestrial impact craters. Initial conditions for this calculation included a meteorite impact velocity of 15 km/s, meteorite mass of 1.67 x 108 kg, with a corresponding kinetic energy of 1.88 x 1016 J (4.5 megatons). A two-dimensional Eulerian finite difference code called SOIL was used for this simulation of a cylindrical iron projectile impacting at normal incidence into a limestone target. For this initial calculation, a Tillotson equation-of-state description for iron and limestone was used with no shear strength. Results obtained for this preliminary calculation of the formation of Meteor Crater are in good agreement with field measurements. A color movie based on this calculation was produced using computer-generated graphics. 19 figures, 5 tables, 63 references

  4. Climate Change Impact on Hydrological Extremes: Preliminary Results from the Polish-Norwegian Project

    Directory of Open Access Journals (Sweden)

    Romanowicz Renata J

    2016-04-01

    Full Text Available This paper presents the background, objectives, and preliminary outcomes from the first year of activities of the Polish–Norwegian project CHIHE (Climate Change Impact on Hydrological Extremes. The project aims to estimate the influence of climate changes on extreme river flows (low and high and to evaluate the impact on the frequency of occurrence of hydrological extremes. Eight “twinned” catchments in Poland and Norway serve as case studies. We present the procedures of the catchment selection applied in Norway and Poland and a database consisting of near-natural ten Polish and eight Norwegian catchments constructed for the purpose of climate impact assessment. Climate projections for selected catchments are described and compared with observations of temperature and precipitation available for the reference period. Future changes based on those projections are analysed and assessed for two periods, the near future (2021–2050 and the far-future (2071–2100. The results indicate increases in precipitation and temperature in the periods and regions studied both in Poland and Norway.

  5. Upper crustal structure beneath East Java from ambient noise tomography: A preliminary result

    International Nuclear Information System (INIS)

    East Java has a fairly complex geological structure. Physiographically East Java can be divided into three zones, i.e. the Southern Mountains zone in the southern part, the Kendeng zone in the middle part, and the Rembang zone in the northern part. Most of the seismic hazards in this region are due to processes in the upper crust. In this study, the Ambient Noise Tomography (ANT) method is used to image the upper crustal structure beneath East Java. We have used seismic waveform data recorded by 8Meteorological, Climatological and Geophysical Agency (BMKG) stationary seismographic stations and 16 portable seismographs installed for 2 to 8 weeks. The data were processed to obtain waveforms fromnoise cross-correlation between pairs of seismographic stations. Our preliminary results indicate that the Kendeng zone, an area of low gravity anomaly, is associated with a low velocity zone. On the other hand, the southern mountain range, which has a high gravity anomaly, is related to a high velocity anomaly as shown by our tomographic images

  6. Preliminary results of the aerosol optical depth retrieval in Johor, Malaysia

    International Nuclear Information System (INIS)

    Monitoring of atmospheric aerosols over the urban area is important as tremendous amounts of pollutants are released by industrial activities and heavy traffic flow. Air quality monitoring by satellite observation provides better spatial coverage, however, detailed aerosol properties retrieval remains a challenge. This is due to the limitation of aerosol retrieval algorithm on high reflectance (bright surface) areas. The aim of this study is to retrieve aerosol optical depth over urban areas of Iskandar Malaysia; the main southern development zone in Johor state, using Moderate Resolution Imaging Spectroradiometer (MODIS) 500 m resolution data. One of the important steps is the aerosol optical depth retrieval is to characterise different types of aerosols in the study area. This information will be used to construct a Look Up Table containing the simulated aerosol reflectance and corresponding aerosol optical depth. Thus, in this study we have characterised different aerosol types in the study area using Aerosol Robotic Network (AERONET) data. These data were processed using cluster analysis and the preliminary results show that the area is consisting of coastal urban (65%), polluted urban (27.5%), dust particles (6%) and heavy pollution (1.5%) aerosols

  7. Preliminary results of CCD observations of Himalia at Yunnan Observatories in 2015

    CERN Document Server

    Peng, H W; Peng, Q Y

    2016-01-01

    In order to study the potential in high precision CCD astrometry of irregular satellites, we have made experimental observations for Himalia, the sixth and irregular satellite of Jupiter. A total of 185 CCD observations were obtained by using the 2.4 m telescope and 1 m telescope at Yunnan Observatories over ten nights. Preliminary analysis for the observations were made, including the geometric distortion, the atmospheric refraction, and also the phase effect. All positions of Himalia are measured relative to the reference stars from the catalogue UCAC4 in each CCD field of view. The theoretical positions of Himalia were retrieved from the IMCCE, while the positions of Jupiter were obtained based on the planetary theory INPOP13C. The results show that the mean (O-C) (observed minus computed) residuals are -0.004 and -0.002 arcsec in right ascension and declination, respectively. The standard deviation of (O-C) residuals are estimated at about 0.04 arcsec in each direction.

  8. Experimental studies in a single-phase parallel channel natural circulation system. Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Bodkha, Kapil; Pilkhwal, D.S.; Jana, S.S.; Vijayan, P.K. [Bhabha Atomic Research Centre, Mumbai (India). Reactor Engineering Div.

    2016-03-15

    Natural circulation systems find extensive applications in industrial engineering systems. One of the applications is in nuclear reactor where the decay heat is removed by natural circulation of the fluid under off-normal conditions. The upcoming reactor designs make use of natural circulation in order to remove the heat from core under normal operating conditions also. These reactors employ multiple vertical fuel channels with provision of on-power refueling/defueling. Natural circulation systems are relatively simple, safe and reliable when compared to forced circulation systems. However, natural circulation systems are prone to encounter flow instabilities which are highly undesirable for various reasons. Presence of parallel channels under natural circulation makes the system more complicated. To examine the behavior of parallel channel system, studies were carried out for single-phase natural circulation flow in a multiple vertical channel system. The objective of the present work is to study the flow behavior of the parallel heated channel system under natural circulation for different operating conditions. Steady state and transient studies have been carried out in a parallel channel natural circulation system with three heated channels. The paper brings out the details of the system considered, different cases analyzed and preliminary results of studies carried out on a single-phase parallel channel system.

  9. Multitemporal Spaceborne SAR Data For Urbanization Monitoring In China: Preliminary Result

    Science.gov (United States)

    Ban, Yifang; Yousif, Osama Adam

    2010-10-01

    The objective of this research is to investigate multitemporal spaceborne SAR data for urbanization monitoring in China. A generalized version of Kittler- Illingworth minimum-error thresholding algorithm, that takes into account the non-Gaussian distribution of SAR images, was tested to automatically classify the change variable derived from SAR multitemporal images into two classes, change and no change. A modified ratio operator was examined for identifying both positive and negative changes by comparing the multitemporal SAR images on a pixel-by-pixel basis. Various probability density functions such as Log normal, Generalized Gaussian, Nakagami ratio, and Weibull ratio models were tested to model the distribution of the change and no change classes. The preliminary results showed that this unsupervised change detection algorithm is very effective in detecting temporal changes in urban areas using multitemporal SAR images. The initial findings indicated that change detection accuracy varies depending on how the assumed conditional class density function fits the histograms of change and no change classes.

  10. Experimental studies in a single-phase parallel channel natural circulation system. Preliminary results

    International Nuclear Information System (INIS)

    Natural circulation systems find extensive applications in industrial engineering systems. One of the applications is in nuclear reactor where the decay heat is removed by natural circulation of the fluid under off-normal conditions. The upcoming reactor designs make use of natural circulation in order to remove the heat from core under normal operating conditions also. These reactors employ multiple vertical fuel channels with provision of on-power refueling/defueling. Natural circulation systems are relatively simple, safe and reliable when compared to forced circulation systems. However, natural circulation systems are prone to encounter flow instabilities which are highly undesirable for various reasons. Presence of parallel channels under natural circulation makes the system more complicated. To examine the behavior of parallel channel system, studies were carried out for single-phase natural circulation flow in a multiple vertical channel system. The objective of the present work is to study the flow behavior of the parallel heated channel system under natural circulation for different operating conditions. Steady state and transient studies have been carried out in a parallel channel natural circulation system with three heated channels. The paper brings out the details of the system considered, different cases analyzed and preliminary results of studies carried out on a single-phase parallel channel system.

  11. Preliminary results on the implantation of a laboratory for the measurement of natural radiocarbon

    International Nuclear Information System (INIS)

    Though the project 'Amazonia I', activity 'Paleoclimatology', sub-project 'hydrologic cycle', the Centro de Energia Nuclear da Agricultura (CENA) from Universidade de Sao Paulo has received recently, from Atomic Energy International Agency a research apparatus for the tranformation of carbon from benzene samples and a liquid scintillator spectrometer of low background, for the detection of natural radiocarbon. In the production of 3ml of benzene, synthetized from oxalic acid P.A. and calcium carbonate P.A., it was obtained a performance of more than 80%; preliminary results were also obtained for shell and coal samples. For the detection of radiocarbon, after optimization of the spectral region, and selection of samples, it was seen that the efficiency of the spectrometer was of the order of 55%, with a base counting rate of 1,3 cmp. The age limit, under the actual operation conditions was 41.600 years 95% (2σ) and 36.700 years for 99% (3σ) considering a time counting of 1000 minutes for the sample and the bacground radiation. (A.C.A.S.)

  12. Integrated Bio-ISRU and Life Support Systems at the Lunar Outpost: Concept and Preliminary Results

    Science.gov (United States)

    Brown, I. I.; Garrison, D. H.; Allen, C. C.; Pickering, K.; Sarkisova, S. A.; Galindo, C., Jr.; Pan, D.; Foraker, E.; Mckay, D. S.

    2009-01-01

    We continue the development of our concept of a biotechnological loop for in-situ resource extraction along with propellant and food production at a future lunar outpost, based on the cultivation of litholytic cyanobacteria (LCB) with lunar regolith (LR) in a geobioreactor energized by sunlight. Our preliminary studies have shown that phototropic cultivation of LCB with simulants of LR in a low-mineralized medium supplemented with CO2 leads to rock dissolution (bioweathering) with the resulting accumulation of Fe, Mg and Al in cyanobacterial cells and in the medium. LCB cultivated with LR simulants produces more O2 than the same organisms cultivated in a high-mineralized medium. The loss of rock mass after bioweathering with LCB suggests the release of O from regolith. Further studies of chemical pathways of released O are required. The bioweathering process is limited by the availability of CO2, N, and P. Since lunar regolith is mainly composed of O, Si, Ca, Al and Mg, we propose to use organic waste to supply a geobioreactor with C, N and P. The recycling of organic waste, including urine, through a geobioreactor will allow for efficient element extraction as well as oxygen and biomass production. The most critical conclusion is that a biological life support system tied to a geobioreactor might be more efficient for supporting an extraterrestrial outpost than a closed environmental system.

  13. Upper crustal structure beneath East Java from ambient noise tomography: A preliminary result

    Energy Technology Data Exchange (ETDEWEB)

    Martha, Agustya Adi [Meteorological, Climatological and Geophysical Agency, Jakarta (Indonesia); Graduate Research on Earthquakes and Active Tectonics, Institut Teknologi Bandung, Bandung (Indonesia); Widiyantoro, Sri [Global Geophysics Group, Institut Teknologi Bandung, Bandung (Indonesia); Center for Disaster Mitigation, Institut Teknologi Bandung, Bandung (Indonesia); Cummins, Phil; Saygin, Erdinc [Research School of Earth Sciences, Australian National University, Canberra (Australia); Masturyono [Meteorological, Climatological and Geophysical Agency, Jakarta (Indonesia)

    2015-04-24

    East Java has a fairly complex geological structure. Physiographically East Java can be divided into three zones, i.e. the Southern Mountains zone in the southern part, the Kendeng zone in the middle part, and the Rembang zone in the northern part. Most of the seismic hazards in this region are due to processes in the upper crust. In this study, the Ambient Noise Tomography (ANT) method is used to image the upper crustal structure beneath East Java. We have used seismic waveform data recorded by 8Meteorological, Climatological and Geophysical Agency (BMKG) stationary seismographic stations and 16 portable seismographs installed for 2 to 8 weeks. The data were processed to obtain waveforms fromnoise cross-correlation between pairs of seismographic stations. Our preliminary results indicate that the Kendeng zone, an area of low gravity anomaly, is associated with a low velocity zone. On the other hand, the southern mountain range, which has a high gravity anomaly, is related to a high velocity anomaly as shown by our tomographic images.

  14. Joint pain and swelling prevalence in residents of different regions of Russian Federation (preliminary results

    Directory of Open Access Journals (Sweden)

    Sh F Erdes

    2004-08-01

    Full Text Available Objective. To reveal in a population sample people with joint pain and swelling. Material and methods. A screening questionnaire for revelation arthritis and arthralgia was filled for each adult resident of 18 years or older. Screening examination was performed in country and city samples. Universal examination was performed among country residents, representative sample was formed for city residents. Results. 23438 residents were screened, mean age was 48,1 ±17,6 years. Women were prevalent - 60%. 8016 were city and 15422 - country residents. Joint pain prevalence was 45%, joint swelling - 27%. These symptoms disappeared with time in 7% and 6% respectively. In other people they became chronic. Population prevalence of joint complaints is connected with sex and depends on age. In people younger than 20 years of age prevalence of joint pain was 9% and swelling - 3%. Conclusion. Preliminary analysis of the screening part of the study showed scale of the joint pathology problem and allowed to get the first data on prevalence of arthralgia and arthritis in Russia.

  15. Trajectory planning method for reduced patient risk in image-guided neurosurgery: concept and preliminary results

    Science.gov (United States)

    Shamir, Reuben R.; Joskowicz, Leo; Antiga, Luca; Foroni, Roberto I.; Shoshan, Yigal

    2010-02-01

    We present a new preoperative planning method to quantify and help reduce the risk associated with needle and tool insertion trajectories in image-guided keyhole neurosurgery. The goal is to quantify the risk of a proposed straight trajectory, and/or to find the trajectory with the lowest risk to nearby brain structures based on pre-operative CT/MRI images. The method automatically computes the risk associated with a given trajectory, or finds the trajectory with the lowest risk to nearby brain structures based on preoperative image segmentation and on a risk volume map. The surgeon can revise the suggested trajectory, add a new one using interactive 3D visualization, and obtain a quantitative risk measure. The trajectory risk is evaluated based on the tool placement uncertainty, on the proximity of critical brain structures, and on a predefined table of quantitative geometric risk measures. Our preliminary results on a clinical dataset with eight targets show a significant reduction in trajectory risk and a shortening of the preoperative planning time as compared to the conventional method.

  16. Aerobic Capacity Following Long Duration International Spaces Station (ISS) Missions: Preliminary Results

    Science.gov (United States)

    Moore, Alan D.; Lee, S.M.C.; Everett, M.E.; Guined, J.R.; Knudsen, P.

    2010-01-01

    Maximum oxygen uptake (VO2max) is reduced immediately following space flights lasting 6%. WRmax also decreased on R+1/2 compared to preflight (Pre: 245+/-69, R+1/2: 210+/-45 W). On R+10, VO2max was 2.86+/-0.62 L(dot)/min, with 2 subjects still demonstrating a loss of > 6% from preflight. WRmax on R+10 was 240+/-49 W. HRmax did not change from pre to post-flight. Conclusions: These preliminary results, from the first 5 of 12 planned subjects of an ongoing ISS study, suggest that the majority of astronauts will experience a decrease in VO2max after long-duration space-flight. Interestingly, the two astronauts with the highest preflight VO2max had the greatest loss on R+1/2, and the astronaut with the lowest preflight VO2max increased by 13%. Thus, maintenance of VO2max may be more difficult in astronauts who have a high aerobic capacity, perhaps requiring more intense in-flight exercise countermeasure prescriptions.

  17. Extraction of metals from automotive shredder residue:Preliminary results of different leaching systems

    Institute of Scientific and Technical Information of China (English)

    Francesco Ferella; Ida De Michelis; Agostino Scocchera; Mario Pelino; Francesco Vegliò

    2015-01-01

    The study is focused on the extraction of valuable metals from automotive shredder residue (ASR) by different leaching solutions. First, ASR samples were roasted at 600 °C to simulate a thermal treatment processing. Distil ed water, citric and sulphuric acid were preliminarily investigated, thus two further full factorial systems entailing H2SO4–H2O2 and H2SO4–H2O2–Fe3+ were tested. The preliminary experimental results showed that 0.1 mol·L−1 H2SO4 solution extracted 100%of Cu, Fe and Zn, whereas citric acid leached 100%of Zn and Pb, 59%of Fe and 62%of Cu;whereas, H2SO4–H2O2 and H2SO4–H2O2–Fe3+(Fenton's) leaching media showed that Cu, Fe and Zn can be extracted simultaneously and completely from the ASR ashes before final disposal.

  18. Preliminary clinical results from the EORTC 11961 trial at the petten irradiation facility

    International Nuclear Information System (INIS)

    Based on the pre-clinical work of the European Collaboration on Boron Neutron Capture Therapy a study protocol was prepared in 1995 to initiate Boron Neutron Capture Therapy (BNCT) in patients at the High Flux Reactor (HFR) in Petten. Bio-distribution and pharmacokinetics data of the boron drug Na2B12H11SH (BSH) as well as the radiobiological effects of BNCT with BSH in healthy brain tissue of dogs were considered in designing the strategy for this clinical Phase I trial. The primary goal of the radiation dose escalation study is the investigation of possible adverse events due to BNCT; i.e. to establish the dose limiting toxicity and the maximal tolerated radiation dose. The treatment is delivered in 4 fractions at a defined average boron concentration in blood. After an observation period of at least 6 months, the dose is increased by 10% for the next cohort. The preliminary results of the first cohort are presented here. The evaluated dose level can be considered to be safe. (author)

  19. PRELIMINARY RESULTS OF QUALITY STUDY OF WATER FROM SMALL MICHALICE RESERVOIR ON WIDAWA RIVER

    Directory of Open Access Journals (Sweden)

    Mirosław Wiatkowski

    2014-10-01

    Full Text Available The paper presents an analysis of water quality of the small Michalice reservoir. A preliminary assessment of the reservoir water quality and its usability was made. The quality of water in the reservoir is particularly important as the main functions of the reservoir are agricultural irrigation, recreation and flood protection . The following physico-chemical parameters of the Widawa River were analyzed: NO3 -, NO2 -, NH4 +, PO4 3-, COD, water temperature, pH and electrolytic conductivity. Main descriptive statistical data were presented for the analyzed water quality indicators. The research results indicate that the reservoir contributed to the reduced concentrations of the following water quality indicators: nitrates, nitrites, phosphates, electrolytic conductivity and COD (in the outflowing water – St.3 in comparison to the water flowing into the reservoir – St.1. In the water flowing out of the Psurów reservoir higher values of the remaining indicators were observed if compared with the inflowing water. It was stated, as well, that analised waters are not vulnerable to nitrogen compounds pollution coming from the agricultural sources and are eutrophic. For purpose obtaining of the précised information about condition of Michalice reservoir water purity as well as river Widawa it becomes to continue the hydrological monitoring and water quality studies.

  20. Long-term results of the maxillary sinus carcinoma with irradiation and intraarterial infusion of 5-FU

    International Nuclear Information System (INIS)

    Therapeutic results of 33 primary cases of maxillary sinus carcinoma treated with irradiation and intraarterial infusion of 5-FU between 1972 and 1984 were analyzed. The 5-year crude survival rate for the group with stage T2 carcinoma (n=10) was 50.0%, and for those with T3 (n=15) and T4 (n=8) it was 46.7% and 25.0%, respectively. The overall 5-year crude survival rate was 42.4%. Eight patients who did not undergo maxillectomy survived for 5 years after irradiation and intraarterial infusion. Recurrence of the tumor after the irradiation and intraarterial infusion occurred in 63.6%, and was frequently observed at the ethmoidal region and the orbita. In the areas in which the tumor extended to regions such as the ethmoid sinus and orbita, which are nourished by arteries other than the maxillary artery, conventional intraarterial infusion was ineffective for complete tumor eradication. Therefore, in most of the patients with advanced maxillary sinus carcinoma, partial or total maxillectomy following combined therapy of intraarterial infusion and irradiation is necessary to improve a prognosis. (author)