WorldWideScience

Sample records for carbono api x65

  1. Effect of Microstructural Parameters on Fatigue Crack Propagation in an API X65 Pipeline Steel

    Science.gov (United States)

    Mohtadi-Bonab, M. A.; Eskandari, M.; Ghaednia, H.; Das, S.

    2016-09-01

    In the current research, we investigate fatigue crack growth in an API X65 pipeline steel by using an Instron fatigue testing machine. To this, first the microstructure of steel was accurately investigated using scanning electron microscope. Since nonmetallic inclusions play a key role during crack propagation, the type and distribution of such inclusions were studied through the thickness of as-received X65 steel using energy-dispersive spectroscopy technique. It was found that the accumulation of such defects at the center of thickness of the pipe body was higher than in other regions. Our results showed that there were very fine oxide inclusions (1-2 µm in length) appeared throughout the cross section of X65 steel. Such inclusions were observed not at the fatigue crack path nor on both sides of the fatigue crack. However, we found that large manganese sulfide inclusions (around 20 µm in length) were associated with fatigue crack propagation. Fatigue experiments on CT specimens showed that the crack nucleated when the number of fatigue cycles was higher than 340 × 103. On fracture surfaces, crack propagation also occurred by joining the microcracks at tip of the main crack.

  2. Effect of Microstructural Parameters on Fatigue Crack Propagation in an API X65 Pipeline Steel

    Science.gov (United States)

    Mohtadi-Bonab, M. A.; Eskandari, M.; Ghaednia, H.; Das, S.

    2016-11-01

    In the current research, we investigate fatigue crack growth in an API X65 pipeline steel by using an Instron fatigue testing machine. To this, first the microstructure of steel was accurately investigated using scanning electron microscope. Since nonmetallic inclusions play a key role during crack propagation, the type and distribution of such inclusions were studied through the thickness of as-received X65 steel using energy-dispersive spectroscopy technique. It was found that the accumulation of such defects at the center of thickness of the pipe body was higher than in other regions. Our results showed that there were very fine oxide inclusions (1-2 µm in length) appeared throughout the cross section of X65 steel. Such inclusions were observed not at the fatigue crack path nor on both sides of the fatigue crack. However, we found that large manganese sulfide inclusions (around 20 µm in length) were associated with fatigue crack propagation. Fatigue experiments on CT specimens showed that the crack nucleated when the number of fatigue cycles was higher than 340 × 103. On fracture surfaces, crack propagation also occurred by joining the microcracks at tip of the main crack.

  3. Correction factors for safe performance of API X65 pipeline steel

    Energy Technology Data Exchange (ETDEWEB)

    Hashemi, Sayyed H. [Department of Mechanical Engineering, the University of Birjand, P.O. Box 97175/615, Birjand (Iran, Islamic Republic of)], E-mail: shhashemi@birjand.ac.ir

    2009-08-15

    Prediction of required Charpy energy for fracture arrest is vital for safe performance of gas transportation pipelines. This is commonly estimated through failure models calibrated in the past on fracture data from combined Charpy tests and full-thickness burst experiments. Unfortunately, such pipeline failure models are unable to correctly predict the minimum arrest toughness of thermo-mechanical controlled rolled (TMCR) steels. To refine the existing failure models, different empirical adjustments have been proposed in recent years. In this paper, similar correction factors were derived from fracture information of instrumented Charpy impact tests on API X65 steel. The contribution of different fracture mechanisms of impact test specimens was determined through energy partitioning analysis. Parts of the energy contribution were correlated then to the source of uncertainty observed in similar experiments. The applied technique was similar to that of previous studies on X70 and X100 steels, and proved to be encouraging in giving consistent results compared to available test data.

  4. Risk of Galvanic Corrosion among API X65, 316L and Inconel 625%API X65、316L不锈钢及Inconel 625间电偶腐蚀风险研究

    Institute of Scientific and Technical Information of China (English)

    田永芹; 常炜; 胡丽华; 贾旭; 周晓红; 邢云颖; 余晓毅; 于湉

    2016-01-01

    ABSTRACT:Objective To determine the galvanic corrosion risk among API X65, 316L and inconel 625.Methods Elec-trochemical corrosion test, standard galvanic corrosion evaluation experiment and simulation experiment were carried out to analyze the corrosion risk.Results The corrosion potential of X65 was around-0.75 V, while that of 316L and 625 potential was both around-0.35 V. For standard galvanic corrosion evaluation experiment, in the open solution or 100 kPa and 500 kPa CO2 solution, the galvanic current of X65-316L was the largest, followed by X65-625 and then 316L-625. Galvanic corrosion oc-curred when X65 met either 316L or 625. For simulation experiment, obvious galvanic corrosion occurred among X65, 316L and 625. There was a serious groove corrosion near the weld joint position in X65. The corrosion rate of X65 without galvanic corrosion was 1.24 mm/a. The galvanic corrosion increased this value. The average galvanic corrosion rate of X65-316L was 1.49 mm/a and that of X65-625 was 1.75 mm/a. The local galvanic corrosion rate of X65-316L was 16.8 mm/a and that of X65-625 was 26.4 mm/a, which was over ten times as high as the corrosion rate of X65 without galvanic corrosion. The galvan-ic corrosion rate of X65 and 316L was larger than that of X65 and 625. There was almost no galvanic corrosion between 316L stainless steel and 625 nickel base alloy.ConclusionGalvanic corrosion risk between X65 and 316L was larger than that be-tween X65 and 625. Galvanic corrosion risk between 316L and 625 was very small.%目的:确定API X65、316L不锈钢及inconel625相互偶接后的电偶腐蚀风险。方法采用电化学测试、标准电偶腐蚀评价实验和腐蚀模拟实验对电偶腐蚀进行分析研究。结果在模拟地层水中,经过电化学测试,X65的自腐蚀电位在-0.75 V左右,316L和625的电位在-0.35 V左右。对于标准电偶腐蚀评价实验,敞口溶液及CO2分压分别为100 kPa和500 kPa的溶液中,X65与316L之间的

  5. Effect of heat treatments on the hydrogen embrittlement susceptibility of API X-65 grade line-pipe steel

    Indian Academy of Sciences (India)

    G Ananta Nagu; Amarnath; T K G Namboodhiri

    2003-06-01

    Delayed failure tests were carried out on hydrogen charged API X-65 grade line-pipe steel in as received (controlled rolled), normalized, and quenched and tempered conditions. The resistance to hydrogen embrittlement was found in the order of controlled rolled $\\gt$ quenched and tempered $\\gt$ normalized. The fracture mode in the hydrogen embrittled steel was ductile.

  6. Comparative study of the microbiological corrosion among an AISI 304L and an API X65; Estudio comparativo de la corrosion microbiologica entre un AISI 304L y un API X65

    Energy Technology Data Exchange (ETDEWEB)

    Diaz S, A.; Arganis J, C.; Luna C, P.; Carapia M, L. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico); Gonzalez F, E. [ITT, Toluca, Estado de Mexico (Mexico)

    2004-07-01

    Metallic samples of AISI 304L sensitized and API X65, were subjected to the action of an inoculated media with reductive sulphate microorganisms (SBR), carrying out electrochemical evaluations by means of the techniques of Polarization Resistance (RP), Tafel extrapolation (ET) and Electrochemical Noise (RE). The generated information was complemented with the analysis and diagnostic of the present damage in the surfaces exposed in both metals. The used electrochemical techniques allow to determine the corrosion velocities associated to each system, establishing that the uniform corrosion is not affected by the effect of the microorganisms; however, electrochemical noise, evidenced the formation of stings associated to the presence of bacteria. (Author)

  7. DESGASTE POR ABRASIÓN DEL ACERO API 5L X65 REVESTIDO CON NIOBIO POR ASPERSIÓN TÉRMICA A PLASMA Y CON INCONEL 625 POR SOLDADURA

    Directory of Open Access Journals (Sweden)

    JOSE MATOS

    2012-01-01

    Full Text Available El objetivo de este trabajo fue evaluar y caracterizar el comportamiento mecánico en desgaste del acero API 5L X65, revestido con niobio en comparación al desempeño del revestimiento de la aleación de inconel 625 empleados en la industria de petróleo y gas. El revestimiento de niobio fue obtenido por el proceso de aspersión térmica a plasma de arco no transferido y el revestimiento inconel 625 por soldadura con electrodo revestido. La resistencia al desgaste por abrasión fue evaluada según la norma Petrobras N-2568, en un tribómetro CTER, la rugosidad y el volumen de material desgastado se determinó a través de perfilometría y la dureza de los revestimientos por microscopia Vickers. Los revestimientos obtenidos fueron caracterizados respecto a su morfología por microscopia electrónica de barrido (MEB y microscopía óptica (MO. La mayor dureza del revestimiento con niobio obtenido puede haber contribuido a reducir la tasa de desgaste en comparación con el revestimiento de inconel 625.

  8. APIs

    CERN Document Server

    Jacobson, Daniel; Woods, Dan

    2011-01-01

    Programmers used to be the only people excited about APIs, but now a growing number of companies see them as a hot new product channel. This concise guide describes the tremendous business potential of APIs, and demonstrates how you can use them to provide valuable services to clients, partners, or the public via the Internet. You'll learn all the steps necessary for building a cohesive API business strategy from experts in the trenches. Facebook and Twitter APIs continue to be extremely successful, and many other companies find that API demand greatly exceeds website traffic. This book offe

  9. Comparative study in the induced corrosion by sulfate reducing microorganisms, in a stainless steel 304L sensitized and a carbon steel API X65; Estudio comparativo de la corrosion inducida por microorganismos sulfatorreductores, en un acero inoxidable 304L sensibilizado y un acero al carbono API X65

    Energy Technology Data Exchange (ETDEWEB)

    Diaz S, A.; Gonzalez F, E.; Arganis J, C.; Luna C, P.; Carapia M, L. [ININ, Carretera Mexico-Toluca Km. 36.5, 52045 Estado de Mexico (Mexico)]. e-mail: ads@nuclear.inin.mx

    2004-07-01

    In spite of the operational experience related with the presence of the phenomenon of microbiological corrosion (MIC) in industrial components, it was not but until the decade of the 80 s when the nuclear industry recognized its influence in some systems of Nuclear Generating Power plants. At the moment, diverse studies that have tried to explain the generation mechanism of this phenomenon exist; however, they are even important queries that to solve, especially those related with the particularities of the affected metallic substrates. Presently work, the electrochemical behavior of samples of stainless steel AISI 304L sensitized is evaluated and the carbon steel APIX65, before the action of sulfate reducing microorganisms low the same experimental conditions; found that for the APIX65 the presence of this type of bacteria promoted the formation of a stable biofilm that allowed the maintenance of the microorganisms that damaged the material in isolated places where stings were generated; while in the AISI 304L, it was not detected damage associated to the inoculated media. The techniques of Resistance to the Polarization and Tafel Extrapolation, allowed the calculation of the speed of uniform corrosion, parameter that doesn't seem to be influenced by the presence of the microorganisms; while that noise electrochemical it distinguished in real time, the effect of the sulfate reducing in the steel APIX65. (Author)

  10. A comparative study on the electrochemical corrosion behavior of iron and X-65 steel in 4.0 wt % sodium chloride solution after different exposure intervals.

    Science.gov (United States)

    Sherif, El-Sayed M

    2014-07-09

    In this work, the results obtained from studying the anodic dissolution of pure iron and API X-65 5L pipeline steel after 40 min and 12 h exposure period in 4.0 wt % NaCl solutions at room temperature were reported. Potential-time, electrochemical impedance spectroscopy, potentiodynamic polarization, and chronoamperometric current-time at constant potential techniques were employed. It has been found that the iron electrode corrodes in the chloride test solutions faster than the API X-65 5L steel does under the same conditions. Increasing the exposure period for the electrodes from 40 min to 12 h showed a significant reduction in the corrosion parameters for both iron and steel in the 4.0 wt % NaCl solution. Results together confirmed clearly that the X-65 steel is superior to iron against corrosion in sodium chloride solutions.

  11. X65管线钢的TRIP效应研究%Study on TRIP effect of X65 pipeline steel

    Institute of Scientific and Technical Information of China (English)

    张德丰; 陆建生; 吕建国; 宋鹏

    2011-01-01

    通过扩展Avrami相变动力学模型、开发线性混合热膨胀模型、应用有限元单胞法,考虑了相变诱导塑性(TRIP)、相变膨胀、热膨胀等机制,建立了热力耦合有限元单胞模型.用该模型研究了X65管线钢分别在0、±50、±100、±150、±200 MPa拉、压单轴外载作用下,以1℃/s的冷速从540℃冷却至480℃的控冷过程,标定了TRIP系数,定量分析了TRIP效应对应变、应力的影响.结果表明:本模型适用于研究X65管线钢中由Greenwood-Johnson机制产生的TRIP效应,TRIP系数为5.35×10;控冷结束,拉应力外载产生的ε占ε的比例最低22%,最高79%;拉、压外载作用下,TRIP效应产生的最高残余拉、压应力分别为346 MPa和-103 MPa的.%A thermo-mechanical coupled finite element unit cell model was established, where the modified Avrami model, the developed linear mixture thermal expansion model and the method of finite element unit cell were utilized. In this model transformation induced plasticity (TRIP), transformation dilatation, thermal expansion are considered. The identification of TRIP parameters was implemented and the effects of TRIP on strain, stress field were analyzed quantitatively during controlled cooling of X65 pipeline steel with a cooling speed of 1 ℃/s in temperatures between 540 ℃ and 480 ℃, under uniaxial tensile or compressive external loading, such as 0, ±50, ±1O0, ± 150 or ±200 MPa. The results show that the model is suitable to study the effect of TRIP from Greenwood-Johnson effect during controlled cooling of X65 pipeline steel. The coefficient of TRIP is 5.35 × 10-5. The minimum and maximum percent of TRIP strain in total strain are 22 % and 79 %respectively under tensile external loading. The maximum residual tensile stress from TRIP effect is 346 MPa under uniaxial tensile external loading, and -103 MPa for compressive condition.

  12. Fracture toughness and safety assessment of X65 offshore pipeline welded joints

    Institute of Scientific and Technical Information of China (English)

    Zhang Li; Zhang Yufeng; Huo Lixing; Deng Caiyan

    2005-01-01

    In this investigation, the mechanical properties and low-temperature fracture toughness of API 5L X65 offshore pipeline welded joints were studied. Structure Integrity Assessment Procedure (SINTAP)-Failure Assessment Diagram (FAD) method was applied to the pipe structure with surface flaw at the weld toe. According to the ISO standard BS7448,the CTOD fracture toughness of the welded joints was determined at the temperature of 0℃. For the heat-affected zone (HAZ) specimens, post-test metallographic analysis was performed to verify that the tip of the crack was located in the coarse crystal zone in order to confirm the validity of the above results. The failure lines of analysis level 1 and 3 of weld metal were derived from the results of the mechanical property test. The assessment was performed, considering the maximum lay stress, residual stress conservatively assumed to be uniform tensile stress, and minimum CTOD value. The results of the assessment showed that pipeline structure with a surface flaw ( the height and length are respectively 2. 2 mm and 5 mm) at the weld toe is safe. This study lays the foundation of application of SINTAP to pipeline structure assessment.

  13. APPLICATION OF SINTAP TO THE SAFETY ASSESSMENT OF X65 PIPELINE STEEL

    Institute of Scientific and Technical Information of China (English)

    Deng Caiyan; Zhang Yufeng; Huo Lixing

    2005-01-01

    The recently developed European flaw assessment procedure, structural integrity assessment procedure(SINTAP) is applied to assessment for welded joints of the API 5L X65 pipeline steel with an assumed embedded flaw and surface flaw at the weld toe. As one of the basic input data, fracture toughness crack tip opening displacement (CTOD) tests are conducted at 0 ℃ and performed according to the requirements of the standard of BS7448. For the heat affected zone (HAZ) specimens, the microstructure observation is performed to insure that the tip of the crack is located in the coarse grain zone. The result explains the dispersity of the test values. In structural integrity assessment procedure-fracture assessment diagram(SINTAP FAD) method, the failure curves of welded joints at level 1 and 3 are derived from the tensile test results. The results of the assessment show that all assessment points are located within the failure lines of analysis level 1 and 3. So the welded joint of the pipeline is safe. This study laid the foundation of application of SINTAP to pipeline structure assessment.

  14. Development and Production of X65 HTP Type Pipeline Steel at Jigang%HTP型X65管线钢的开发与生产

    Institute of Scientific and Technical Information of China (English)

    刘晓东; 孙玮

    2007-01-01

    介绍了济钢在3 200/3 500 mm双四辊轧机上首次大规模研制生产X65管线钢的工艺和性能.所研制的管线钢采用低C、S、P和高Nb、无V、Mo的成分设计,有低的碳当量CE(≤0.34)和PCM(≤0.17).应用精轧机HTP和ACC快速冷却工艺获得针状铁素体组织,采用堆垛缓冷实现热扩散处理,获得优良性能.采用所开发的X65管线钢板制成的直缝埋弧焊钢管具有良好的力学性能和焊接性能.

  15. Uma breve revisão histórica do desenvolvimento da soldagem dos aços API para tubulações A brief history review of development on API steels welding for pipeline

    Directory of Open Access Journals (Sweden)

    Jaime Casanova Soeiro Junior

    2013-06-01

    Full Text Available Este trabalho enfoca o desenvolvimento dos aços API para tubulações desde o aço API 5L X42, desenvolvido em 1948, através de laminação a quente seguida de tratamento térmico. Desde então foram feitos diferentes desenvolvimentos visando aumentar a resistência mecânica e a tenacidade, além de melhorar a soldabilidade. Entre eles, a adição de elementos de liga, produzindo os aços ARBL e a utilização de rotas de processamento termomecânico durante a laminação. Inicialmente a rota utilizada era a laminação a quente controlada (TMCR, com utilização de elemento microligante como Nb para os aços X60 e o conjunto Nb e V para os aços X65 e X70, associado a uma redução do teor de carbono. Posteriormente foi implantada a rota de fabricação do aço por laminação controlada seguida de resfriamento controlado (TMCP, com redução de carbono e adição de Nb e Ti para os aços X80, e adições de Mo, Nb, Be Ti para os X100. A redução do carbono foi motivada também para melhorar a sua soldabilidade e, por este motivo, estes aços são soldados por diferentes processos de soldagem, como o eletrodo revestido. Desenvolvimentos recentes com raiz feita com MAG-TC e enchimento com arame tubular tem dado resultados animadores.This paper is a brief history on the development of pipelines steels since the API 5L X42 steel, developed in 1948 by hot rolling followed by heat treatment. Subsequently different developments were made to increase the strength and toughness of these materials, and to improve their weldability. Among them, the addition of microalloying elements, producing HSLA steels and thermomechanical processing routes during hot rolling. Initially the route used was the controlled hot rolling (TMCR, together with microalloying element such as Nb for X60 steel and Nb plus V for X65 and X70 steels, associated with a reduction in carbon content. Later, the thermomechanical controlled process (TMCP manufacturing route was

  16. X65 Steel Subsea Pipeline in CO2/H2S Conditions%X65钢海管在CO2/H2S环境中的腐蚀研究

    Institute of Scientific and Technical Information of China (English)

    刘晖; 杨秘; 向安; 王聚锋; 赵东胜; 张立娜; 刘智勇; 李晓刚

    2012-01-01

      中海石油(中国)有限公司天津分公司为了节能减排,在渤海湾某油田开展了天然气利用项目,天然气外输海管选用X65管线钢铺设完成.随着油田不断深入开发,天然气中CO2和H2S含量都达到了较高水平,使该海底管线在运行过程中面临潜在的不确定性腐蚀风险.因此,本文研究了在不同运行工况条件下的X65钢海管焊缝区及热影响区的腐蚀形态和腐蚀规律.试验结果表明,在管线钢的焊缝区和热影响区存在不同程度的均匀腐蚀,而点蚀相对比较轻微;试样整体均匀腐蚀速率达0.1~0.3mm/a,属于中等偏高的腐蚀程度;pH降低、温度升高会使腐蚀速率增大,在管线运行和维护过程中需针对均匀腐蚀采取控制措施.本研究可以为今后海底管线选材、焊接工艺以及后期运维等工作提供借鉴.%  CNOOC (China) Limited-Tianjin carried out an offshore NG utilization project in Bohai Bay of China for energy saving and emission reduction, and API 5L X65 steel was selected for the subsea NG transmission pipeline. Whereas, CO2 and H2S content in NG is increasing along with the continuous and in-depth development of offshore oilfield, and high levels of souring gases may lead to unknown corrosion risks towards the subsea pipeline. Therefore, this paper studies on the corrosion forms and corrosion regularity of weld and heat-affected zone (HAZ) in the X65 steel pipeline under different running conditions. Results of the experiment show that uniform corrosion of varying degrees existed at both weld and HAZ, however, pitting corrosion is relatively slight. The total corrosion rate of the coupon reached 0.1-0.3 mm/a which is medium to high levels of corrosion, and the corrosion rate increased in lower pH and higher temperature in the experiment, so control measures towards uniform corrosion should be taken in its running and maintenance process. Thus, this study would be a significant reference for

  17. Micro Structural Comparison of Friction Stir Weldment and Shielded Metal Arc Welding in API-X65 Pipe Line

    Directory of Open Access Journals (Sweden)

    Amin Shahinfar

    2015-04-01

    Full Text Available The study was conducted to investigate the microstructure and microhardness properties of the friction stir welded zones and shielded metal arc welded. Microstructural analysis of the weld was carried out using optical microscopy. Under FSW process base metal microstructure fully changed. Different heat inputs were obtained using a fix travel (welding speed in combination with several spindle speeds. Heat input during welding process had a significant influence on the microstructure and mechanical proprieties in the various weld regions.it can be concluded that with decrease in heat input the bainitic structure in the hard zone becomes finer and so hard zone hardness increase.

  18. Helioviewer API

    Data.gov (United States)

    National Aeronautics and Space Administration — The Helioviewer Project maintains a set of Public APIs with the goal of improving access to solar and heliospheric datasets to scientists, educators, developers,...

  19. Recalls API

    Data.gov (United States)

    General Services Administration — This Recalls API allows you to tap into a list of (1) drug and food safety recalls from the Food and Drug Administration, Food Safety and Inspection Service, and...

  20. Jobs API

    Data.gov (United States)

    General Services Administration — This Jobs API returns job openings across the federal government and includes all current openings posted on USAJobs.gov that are open to the public and located in...

  1. X65级高频焊接钢管爆裂原因分析%Cause Analysis on Bursting of X65 High Frequency Welded Steel Pipe

    Institute of Scientific and Technical Information of China (English)

    张良; 罗金恒; 冯耀荣; 张华; 张广利

    2011-01-01

    Bursting reasons for the φ457 mm× 7.1 mm X65 grade high frequency welded (HFW) pipeline was analyzed by means of chemical compositions analysis, mechanical properties test, metallographic examination and scanning electron microscope analysis.The results show that existing cold welding defects in the welding line and disqualification of impact ductility of the welding line were main reasons for the bursting.The effective bearing area reduced because of the cold welding defects and the original cracks initiated and expanded in the welding line.At the same time the ability of resistance the crack spreading was worsened because of low impact ductility of the welding line.So the X65 grade pipeline burst at the welding line under the force of hydraulic pressure test.%通过化学成分分析、力学性能测试、金相检验以及扫描电镜分析等方法对某规格为φ457 mm×7.1 mm的X65级高频焊(HFW)钢管水压试验时发生爆裂的原因进行了分析.结果表明:钢管爆裂失效是由于其直焊缝上存在冷焊缺陷以及焊缝冲击韧度不合格所致;焊缝中存在冷焊缺陷使其有效承载面积减小,原始裂纹在冷焊缺陷处萌生并扩展,加之焊缝冲击韧度低,抗裂纹扩展能力差,在水压试验压力作用下最终导致该钢管于焊缝处失稳爆裂.

  2. X65管线厚板控制冷却时的相变效应%Transformation Effect During Controlled Cooling of X65 Heavy Pipeline Plate

    Institute of Scientific and Technical Information of China (English)

    张德丰; 陆建生; 宋鹏; 吕建国

    2012-01-01

    为明确相变效应对X65管线厚板控制冷却的影响,通过开发线性混合热膨胀模型、拓展Avrami相变动力学模型和应用Leblond模型建立了热力耦合有限元模型.用该模型研究了X65管线厚板在上下层流冷却系数分别为3和1 kW/(m2·K)的非对称控制冷却时,相变效应对温度、残余应力和应变的影响.结果表明:相变期间,潜热减缓心部和下表面的冷却速度达50%、25%;潜热和TRIP效应分别产生峰值为89、- 89 MPa,并且130、- 170 MPa的应力可减小整体残余应力;相变膨胀产生峰值为723、- 479 MPa的组织应力决定了整体残余应力大小及分布.%To study the phase transformation effect during the controlled cooling of X65 heavy pipeline plate, a thermomechanical coupled finite element model was established, where the developed linear mixture thermal expansion model, the modified Avrami transformation dynamics model, and the Leblond model were combined. Using the model, the influence of transformation effect on temperature, residual stress, and strain was studied during the asymmetric controlled cooling of X65 heavy pipeline plates with 3 kW/( m ·K) laminar cooling coefficient on top surface and 1 kW/( m ·K) on bottom surface. The result shows that latent beat slowed the coaling speed of inner and bottom surface by 50% and 25% , respectively, during the phase transformation. Peak stresses, 89 MPa and -89 MPa, were induced due to latent heat, and 130 MPa and - 170 MPa from TRIP (transformation induced plasticity) effect. Because of the coexistence of tensile and compressive stresses caused by latent heat and TRIP effect, the overall residual stresses were reduced. Moreover, the magnitude and distribution of the overall residual stresses were dependent significantly on the structural stress with peak values of 723 MPa and - 479 MPa from transformation dilatation.

  3. Filamentos de carbono en hormigones

    Directory of Open Access Journals (Sweden)

    J. Vera-Agulló

    2010-01-01

    Full Text Available En el presente artículo se exponen las principales ventajas de las fibras de carbono en su aplicación como refuerzo en hormigones, haciendo también mención a sus importantes limitaciones económicas.

  4. Mechanism of protective film formation during CO2 corrosion of X65 pipeline steel

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Electrochemical techniques,X-ray diffraction (XRD),and scanning electron microscopy (SEM) were applied to study the corrosion behaviors of X65 steel in static solution with carbon dioxide (CO2 at 65℃.The results show that iron carbonate (FeCO3deposits on the steel surface as a corrosion product scale.This iron carbonate scale acts as a barrier to CO2 corrosion,and can reduce the general corrosion rate.The protection ability of the scale is closely related to the scale morphological characteristics.

  5. Drug Interaction API

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Interaction API is a web service for accessing drug-drug interactions. No license is needed to use the Interaction API. Currently, the API uses DrugBank for its...

  6. 复合管X65/316L在模拟产出水中的电偶腐蚀行为%Galvanic Corrosion Behaviors of X65-316L Bimetal Tube in Simulated Production Water

    Institute of Scientific and Technical Information of China (English)

    邓洪达; 曾顺鹏

    2015-01-01

    海洋天然气输送用复合金属管内外层因内层金属输送介质渗漏将构建电偶对,加速外层金属腐蚀.本工作采用浸泡试验和电化学技术分析X65-316L电偶对在模拟产出水中的电偶腐蚀行为.采用SEM观察电偶对金属腐蚀前后形貌变化;分析X65和316L偶接前后开路电位(OCP)和偶接电流密度(Jcc)随时间的变化曲线,以及其对电化学参数的影响.结果显示,X65-316L电偶对在模拟产出水中X65为阳极,316L为阴极;与偶接前相比,X65腐蚀速率增加,316L腐蚀速率下降,同时X65阴极极化率减小,316L阳极极化率增加.

  7. Improving fatigue performance of welded joints of X65 pipeline steel by UIT

    Institute of Scientific and Technical Information of China (English)

    Liu Jinming; Chen Tong; Zhang Yufeng

    2005-01-01

    Treating weld toes properly can improve the fatigue performance. Ultrasonic impact treatment (UIT) is a more effective and convenient method to enhance the fatigue strength of welded joints and suchlike structures. Fatigue tests were conducted on the specimens made of X65 pipeline steel. The test specimens were investigated on the fatigue strength and the fatigue life at the same stress range level by comparing the ones peened by UIT with the others without the treatment: the fatigue strength of the specimens as UIT, 90% of the fatigue strength of the base mental, is increased by 38% compared with that of as welded only; the fatigue life of the ones as UIT is prolonged by 11 multiples of the ones as welded only.

  8. Study of an API migration for two XML APIs

    NARCIS (Netherlands)

    Bartholomei, T.T.; Czarnecki, K.; Lämmel, R.; Storm, T. van der; Brand, M.G.J. van den; Gasevic, D.; Gray, J.

    2010-01-01

    API migration refers to adapting an application such that its dependence on a given API (the source API) is eliminated in favor of depending on an alternative API (the target API) with the source and target APIs serving the same domain. One may attempt to automate API migration by code transformatio

  9. Analyzing the Change-Proneness of APIs and web APIs

    NARCIS (Netherlands)

    Romano, D.

    2015-01-01

    Analyzing the Change-Proneness of APIs and web APIs APIs and web APIs are used to expose existing business logic and, hence, to ease the reuse of functionalities across multiple software systems. Software systems can use the business logic of legacy systems by binding their APIs and web APIs. With t

  10. Healthcare Finder API

    Data.gov (United States)

    U.S. Department of Health & Human Services — All of the data used on the Finder.HealthCare.gov web application is available through this API. There are multiple collections of data available through the API. 1....

  11. NASA Techport API

    Data.gov (United States)

    National Aeronautics and Space Administration — The NASA TechPort system provides a RESTful web services API to make technology project data available in a machine-readable format. This API can be used to export...

  12. Android quick APIs reference

    CERN Document Server

    Cinar, Onur

    2015-01-01

    The Android Quick APIs Reference is a condensed code and APIs reference for the new Google Android 5.0 SDK. It presents the essential Android APIs in a well-organized format that can be used as a handy reference. You won't find any technical jargon, bloated samples, drawn out history lessons, or witty stories in this book. What you will find is a software development kit and APIs reference that is concise, to the point and highly accessible. The book is packed with useful information and is a must-have for any mobile or Android app developer or programmer. In the Android Quick APIs Refe

  13. Processing, basic characterization and standard dielectric measurements on PLZT x/65/35 (4 ≤ x ≤ 11) ceramics

    Science.gov (United States)

    Pytel, Krzysztof; Suchanicz, Jan; Livinsh, Maris; Sternberg, Andris

    2014-11-01

    The influence of external stress (0-800 bar) on the dielectric properties of lead lanthanum zirconium titanate (PLZT) x/65/35 (4 ≤ x ≤ 11) ceramics was investigated. Applying uniaxial pressure leads to a change in the peak intensity of the electric permittivity (ɛ), in its frequency dispersion as well as in the dielectric hysteresis. The peak intensity of ɛ becomes broader and shifts to lower temperatures for PLZT x/65/35 with x = 4, 7, 9.75 and 11, with increasing pressure, on heating. It was concluded that applying uniaxial pressure induces an increase of Tm, and thus has a similar effect as the increase of the Ti ion concentration in the lead zirconium titanate (PZT) system. Results based on nanoregion switching processes under combined electromechanical loading were interpreted. Studies clearly showed that applied stress has a significant influence on the dielectric properties of PLZT ceramics.

  14. Study on H2S stress corrosion test of welded joint for X65 pipeline steel and numerical analysis

    Institute of Scientific and Technical Information of China (English)

    金晓军; 霍立兴; 张玉凤; 白秉仁; 李晓巍; 曹军

    2004-01-01

    The susceptibility of welded joint for the X65 pipeline steel to H2S stress corrosion cracking (SCC) is investigated. SCC tests on the steel are carried out in the environment based on NACE TM-01-77 solution with saturated gaseous H2S. The threshold stress intensity factor and crack propagation velocity are calculated according to wedge-opening loading (WOL) specimens. The three-dimensional elastic-plastic finite element analysis of WOL specimens is performed by using the FEM programming package ANSYS. Stress field and concentration of hydrogen distribution property ahead of the crack tip are obtained. This paper surveyed the microstructure of welded joint and studied on the mechanical properties of X65 pipeline steel. It provides experimental basis for studying stress corrosion. The results of numerical analysis are consistent with conclusions of stress corrosion test.

  15. API Global Sourcing Strategies 2010.

    Science.gov (United States)

    Bennett, Shannon

    2010-09-01

    The API Global Sourcing Strategies 2010 Conference, held in Berlin, included topics covering new developments in the field of global sourcing of active pharmaceutical ingredients (APIs). This conference report highlights selected presentations on development in Eastern API markets, specifically India and China, factors influencing changes in global API sourcing, and risk mitigation in API sourcing.

  16. TA1/X65复合板焊接工艺及焊缝组织和性能研究%Research on Welding Process, Microstructure and Mechanical Property of TA1/X65 Clad Plates

    Institute of Scientific and Technical Information of China (English)

    杨军; 毕宗岳; 牛辉; 刘海璋; 张万鹏; 田磊; 黄晓江; 张超

    2015-01-01

    采用TIG+MIG+MAG焊接工艺对TA1/X65复合板进行了以V/Cu作为中间过渡填充金属的板-板对接焊试验。利用金相显微镜、扫描电镜、 X射线衍射、 EDS能谱面扫描和显微硬度试验,研究了焊缝区组织特征、界面元素分布、主要物相与显微硬度分布。研究结果表明,坡口设计和过渡金属纯度及各元素间物理、化学特性差异对焊接质量有较大影响。探讨了焊缝区裂纹缺陷的形成及脆硬金属间化合物的产生等问题,为TA1/X65钛钢复合板工程化焊接及焊接中易出现问题的规避和解决积累了经验。%Adopting the welding process of TIG(gas tungsten arc welding)+MIG(metal inert-gas welding)+MAG(metal active-gas welding) to carry out plate-plate butt welding test, with V/Cu as transition filler metal. By using optical microscopy, scanning electron microscopy, X-ray diffraction, EDS element mapping and microhardness test, the microstructure characteristics of weld area, interface element distribution, main phase and microhardness distribution were investigated. The results indicated that the welding quality of TA1/X65 pipeline steel clad plates butt joints was greatly influenced by weld groove design, transition-metals purity and differences between the physical and chemical properties. It also discussed some problems, such as the formation of weld area crack defects, the generation of brittle intermetallic compounds etc., which provide experience for avoiding and solving some problems easily appeared in titanium TA1/X65 steel clad plates engineering welding.

  17. Calculation and comparison between alternate and continuous controlled cooling technology for X65 pipeline steel plate%X65管线钢板交替与连续控冷工艺的计算与比较

    Institute of Scientific and Technical Information of China (English)

    张德丰; 陆建生; 吕建国; 宋鹏; 杜重麟

    2012-01-01

    为减小X65管线钢板控制冷却后的残余应力和翘曲,通过开发线性混合热膨胀模型、拓展Avrami相变动力学模型和应用Leblond的相变诱发塑性(TRIP)模型建立了热力耦合有限元模型,考虑了控冷时的弹塑性变形、热膨胀、相变潜热、相变膨胀、TRIP等所有物理效应.用该模型研究了2种控制冷却工艺下X65管线钢板的温度、残余应力、残余应变及翘曲.结果表明:与连续控冷相比,交替控冷使板的温度进一步降低7℃;上表面一侧的残余拉应力峰值进一步减小44 MPa;下表面一侧的残余总压应变峰值进一步增加0.001;翘曲由0.54×10-3减至0.09×10-3;故交替控冷可降低板内的残余应力,并减小翘曲.%To decrease the residual stress and warping of X65 pipeline steel plate after controlled cooling, a thermo-mechanical coupled FEM model was established according to linear mixture thermal expansion model, modified Avrami transformation dynamics model and Leblond transformation induced plasticity (TRIP) model. All relevant physical effects of elastoplastic deformation, thermal expansion, latent heat, transformation dilatation and TRIP effect were considered in the FEM model. Temperature, residual stress, residual strain and warping of X65 pipeline steel plate were analyzed by the proposed model under two controlled cooling technologies. The results show that the temperature of plate under alternate controlled cooling is 7 ℃ less than that under continuous controlled cooling. The residual tensile stress peak value near top surface is decreased by 44 Mpa with enhanced residual compressive strain peak value of 0.001 near bottom surface, while the warping is reduced from 0. 54 × 10-3 to 0. 09 × 10-3. Alternate controlled cooling can reduce residual stress and warping of plate.

  18. Electrochemical Investigation of the Corrosion of Different Microstructural Phases of X65 Pipeline Steel under Saturated Carbon Dioxide Conditions

    Directory of Open Access Journals (Sweden)

    Yuanfeng Yang

    2015-05-01

    Full Text Available The aim of this research was to investigate the influence of metallurgy on the corrosion behaviour of separate weld zone (WZ and parent plate (PP regions of X65 pipeline steel in a solution of deionised water saturated with CO2, at two different temperatures (55 °C and 80 °C and at initial pH~4.0. In addition, a non-electrochemical immersion experiment was also performed at 80 °C in CO2, on a sample portion of X65 pipeline containing part of a weld section, together with adjacent heat affected zones (HAZ and parent material. Electrochemical impedance spectroscopy (EIS was used to evaluate the corrosion behaviour of the separate weld and parent plate samples. This study seeks to understand the significance of the different microstructures within the different zones of the welded X65 pipe in CO2 environments on corrosion performance; with particular attention given to the formation of surface scales; and their composition/significance. The results obtained from grazing incidence X-ray diffraction (GIXRD measurements suggest that, post immersion, the parent plate substrate is scale free, with only features arising from ferrite (α-Fe and cementite (Fe3C apparent. In contrast, at 80 °C, GIXRD from the weld zone substrate, and weld zone/heat affected zone of the non-electrochemical sample indicates the presence of siderite (FeCO3 and chukanovite (Fe2CO3(OH2 phases. Scanning Electron Microscopy (SEM on this surface confirmed the presence of characteristic discrete cube-shaped crystallites of siderite together with plate-like clusters of chukanovite.

  19. Production of Baosteel X65 High Strength and High Toughness Pipeline Steel%宝钢X65高强度高韧性管线用板卷钢的生产

    Institute of Scientific and Technical Information of China (English)

    郑磊; 陈钰珊

    2001-01-01

    This article introduces the development, production andapplication of Baosteel X65 high strength and high toughness pipeline steel . Baosteel has mastered the modern pipeline steel production and quality control technology, the product's quality is stable and meet the pipeline steel plate demand requirements of customers. It is not only solved the problem of long distance pipeline steel relying on import, realized import substitute , and also successfully applied on pipeline project both home and abroad.%介绍了宝钢发展X65高强度高韧性管线钢所进行的研制、生产及应用情况。宝钢已较好地掌握了现代管线钢的生产和质量控制技术,产品质量稳定,满足国内外用户对管线钢板卷的需求。不仅解决了我国长输管线用钢长期依靠进口的问题,产品能替代进口,并在国外管线工程上得到了成功的应用。

  20. Google Ajax Search API

    CERN Document Server

    Fitzgerald, Michael

    2007-01-01

    Use the Google Ajax Search API to integrateweb search, image search, localsearch, and other types of search intoyour web site by embedding a simple, dynamicsearch box to display search resultsin your own web pages using a fewlines of JavaScript. For those who do not want to write code,the search wizards and solutions builtwith the Google Ajax Search API generatecode to accomplish common taskslike adding local search results to a GoogleMaps API mashup, adding videosearch thumbnails to your web site, oradding a news reel with the latest up todate stories to your blog. More advanced users can

  1. The Study of Controlled Cooling Technology and Warping of X65 Heavy Pipeline Plate%X65厚管线板控冷工艺与翘曲分析

    Institute of Scientific and Technical Information of China (English)

    张德丰; 陆建生; Thomas Antretter; 吕建国; 宋鹏

    2011-01-01

    A thermo-mechanical coupled finite element model is established, which combines the modified Avrami transformation dynamics model, the linear mixture thermal expansion model, and the Leblond transformation induced plasticity (TRIP)model. The model considers latent heat, transformation dilatation, TRIP effect, as well as thermal expansion and elasto plastic deformation. The influence of three different controlled cooling modes on temperature field and stress, strain field of X65 heavy pipeline plate is simulated and the warping of plate is analyzed. The result shows that the main reason of warping is the temperature difference between the top and bottom surfaces from unsymmetric cooling, which causes the unsymmetric distribution of stress and strain field. Alternate cooling, in which laminar cooling and air cooling appear alternately, decreases the temperature difference and reduces the magnitude of warping strongly. To avoid warping and to realize the uniformity of properties, it is more effective to maintain the cooling homogeneity between the top and bottom surface of plate during controlled cooling, and to use alternate cooling.%通过扩展Avrami相变动力学模型、开发线性混合热膨胀模型和使用Leblond相变诱导塑性(TRIP)模型建立了X65厚管线板控冷过程的热力耦合有限元模型,全面考虑了相变潜热、相变膨胀、TRIP效应、热膨胀等机制.用该模型对3种控冷模式下X65厚管线板控冷过程的温度场和应力/应变场进行了模拟,并分析了控冷模式对翘曲变形的影响.结果表明:不对称冷却产生的上下表面间的温差所导致的应力/应变场的不对称分布是材料翘曲的根本原因;交替冷却不仅可降低温差,还可大幅减小材料的翘曲;实现上下表面对称冷却和采用交替冷却是保证产品平直和性能均匀的有效方法.

  2. HTP型X65级管线钢连续冷却相变的研究%Research on Continuous Cooling Phase Transformation of HTP Type X65 Grade Pipeline Steel

    Institute of Scientific and Technical Information of China (English)

    黄明浩; 黄国建; 徐烽; 孔祥磊

    2009-01-01

    利用Gleeble-3800热摸拟试验机,测定了HTP型X65级管线钢的动态CCT曲线,并通过光学显微镜和电子显微镜(SEM和TEM)对连续冷却后的组织和第二相析出物进行了详细观察和分析.随着冷却速度的提高,在连续冷却转变组织中依次出现多边形铁素体、珠光体、针状铁素体,且各阶段冷却后试样的硬度也逐渐增加,M/A数量逐渐增多,分布越来越均匀,第二相析出物增多且变得弥散细小.

  3. Corporate Consumer Contact API

    Data.gov (United States)

    General Services Administration — The data in the Corporate Consumer Contact API is based on the content you can find in the Corporate Consumer Contact listing in the Consumer Action Handbook (PDF)....

  4. Mars Rover Photos API

    Data.gov (United States)

    National Aeronautics and Space Administration — This API is designed to collect image data gathered by NASA's Curiosity, Opportunity, and Spirit rovers on Mars and make it more easily available to other...

  5. GIBS API for Developers

    Data.gov (United States)

    National Aeronautics and Space Administration — API using Global Imagery Browse Services (GIBS) designed to deliver global, full-resolution satellite imagery to users in a highly responsive manner, enabling...

  6. 复合管X65/316L在模拟产出水中电偶腐蚀行为研究

    Institute of Scientific and Technical Information of China (English)

    邓洪达[1; 曾顺鹏[2; 曹献龙[1; 兰伟[1

    2015-01-01

    海洋天然气输送用复合金属管由于内层金属穿孔常发生内外层问电偶腐蚀。本文采用浸泡试验和电化学技术分析X65—316L构成电偶对在模拟产出水中电偶腐蚀行为。采用SEM观察腐蚀前后形貌变化;分析X65和316L偶接前后开路电位(OCP)和偶接电流(Icc)随时间变化,以及电化学参数变化。结果显示,X65—316L电偶对在模拟产出水中X65为阳极,316L为负极;与偶接前相比,X65腐蚀速率增加,316L腐蚀速率下降,同时X65阴极极化率减小,316L阳极极化率增加。

  7. IBM System i APIs at Work

    CERN Document Server

    Vining, Bruce; Hawkins, Ron

    2007-01-01

    This new edition of the bestselling i5 application programming interface (API) book includes powerful new APIs and updated code to give programmers a working knowledge of the APIs available under i5/OS. Using real business-world examples, this book explains APIs that serve webpages, list APIs, APIs that work with user spaces, dynamic index APIs, APIs that retrieve system values, job information and job queue information APIs, APIs that work with data queues, APIs for error handling and message handling, and spool file APIs, among many others. Completely revised and including eight new chapters

  8. X65钢和3Cr钢作为海底管道用钢抗CO2腐蚀性能研究%Research on the CO2 corrosion resistance of X65 and 3Cr steels applied to subsea pipeline

    Institute of Scientific and Technical Information of China (English)

    胡丽华; 常炜; 张雷; 李忠涛; 于湉; 许立宁; 路民旭

    2011-01-01

    The high-pressure high temperature au toclave was used to simulate the typical corrosion environment for oil and gas pipeline, and the CO2 corrosion resistance of X65 and 3Cr steels applied to subsca pipeline was researched.The corrosion rates of both X65 and 3Cr steels were low in mild corrosion environment, so we could choose X65 steel in this environment.With temperature and CO2 par tial pressure increasing, the CO2 corrosion resistance of 3Cr was superior to X65 steel; the average corro sion rate of 3Cr steel was obviously lower than X65 in the middling corrosion environment and 3Cr steel can avoid local corrosion in the middling and severe corrosion environments, so the 3Cr steel was more appropriate than X65 steel in such corrosion environ ment.The corrosion product scale enriched with Cr element was formed on the surface of the steel to protect the matrix from corrosion, which was the main reason that the CO2 corrosion resistance of 3Cr steel was superior to that of X65.%用高温高压反应釜模拟油气输送管道典型腐蚀环境,研究X65钢和3Cr钢作为海底管道用钢的抗CO2腐蚀性能.在温和腐蚀环境,X65钢与3Cr钢的平均腐蚀速率均较低,使用X65钢是安全的.随着温度和CO2分压提高,与X65钢相比3Cr钢表现出更优越的抗CO2腐蚀性能:在中等腐蚀环境3Cr钢平均腐蚀速率较X65钢大幅降低,在中等和苛刻腐蚀环境3Cr钢可有效抑制局部腐蚀的发生;在这样的腐蚀条件下,3Cr钢作为海底管道用钢较X65钢安全.3Cr钢较X65钢抗CO2腐蚀性能提高的主要原因是表面形成了富Cr的腐蚀产物膜,结构致密,对基体起到了有效的保护作用.

  9. X65厚管线板控冷时的相变潜热及TRIP效应%Latent heat and TRIP effect of X65 heavy pipeline plate during controlled cooling

    Institute of Scientific and Technical Information of China (English)

    张德丰; 陆建生; 宋鹏; 林清华; 吕建国

    2011-01-01

    通过开发线性混合热膨胀模型、使用Leblond相变诱导塑性(TRIP)模型和拓展Avrami相变动力学模型建立了热力耦合有限元模型,考虑了相变潜热、相变膨胀、TRIP效应、热膨胀等机制.用该模型分析了X65厚管线板从860℃至低温的非对称(上下表面层流冷却系数分别为3,1mW/mm2K)控冷过程,定量研究了相变潜热、TRIP效应对温度、残余应力的影响.结果表明:相变期间,潜热升温52.7℃,并减缓下表面和心部的温降分别为50%,25%;控冷终了,潜热提高板温44℃.潜热和TRIP效应分别产生峰值为±89M%Based on the developed linear mixture thermal expansion model,the Leblond transformation induced plasticity(TRIP)model,and the modified Avrami transformation dynamics model,a thermo-mechanical coupled finite element model was established,which considered latent heat,transformation dilatation,TRIP effect,thermal expansion,and so on.By the model,the influence of latent heat,TRIP effect on temperature and residual stress was investigated quantitatively during unsymmetrical controlled cooling of X65 heavy pipeline plate from 860℃ to low temperature with 3mW/mm2K laminar cooling coefficient on top surface and 1mW/mm2K laminar cooling coefficient on bottom surface.The results show that the latent heat enhances about 52.7℃ during phase transformation and the cooling speed of bottom surface and inner slows 50% and 25% respectively because of the increasing of latent heat,and the latent heat increases the temperature of plate 44℃ finally.The magnitude and distribution of residual stress are influenced by shifting the stress peak due to latent heat and TRIP effect.

  10. Contracting the Facebook API

    Directory of Open Access Journals (Sweden)

    Ben Rubinger

    2010-09-01

    Full Text Available In recent years, there has been an explosive growth in the popularity of online social networks such as Facebook. In a new twist, third party developers are now able to create their own web applications which plug into Facebook and work with Facebook's "social" data, enabling the entire Facebook user base of more than 400 million active users to use such applications. These client applications can contain subtle errors that can be hard to debug if they misuse the Facebook API. In this paper we present an experience report on applying Microsoft's new code contract system for the .NET framework to the Facebook API.We wrote contracts for several classes in the Facebook API wrapper which allows Microsoft .NET developers to implement Facebook applications. We evaluated the usefulness of these contracts during implementation of a new Facebook application. Our experience indicates that having code contracts provides a better and quicker software development experience.

  11. Mars Atmospheric Aggregation System API

    Data.gov (United States)

    National Aeronautics and Space Administration — The {MAAS} API is an open source REST API built to help make it easier and more efficient to build interactive applications that want to utilize the wealth of...

  12. Data.gov CKAN API

    Data.gov (United States)

    General Services Administration — The data.gov catalog is powered by CKAN, a powerful open source data platform that includes a robust API. Please be aware that data.gov and the data.gov CKAN API...

  13. Butt Welding of 2205/X65 Bimetallic Sheet and Study on the Inhomogeneity of the Properties of the Welded Joint

    Science.gov (United States)

    Gou, Ning-Nian; Zhang, Jian-Xun; Wang, Jian-Long; Bi, Zong-Yue

    2017-03-01

    The explosively welded 2205 duplex stainless steel/X65 pipe steel bimetallic sheets were butt jointed by multilayer and multi-pass welding (gas tungsten arc welding for the flyer and gas metal arc welding for the transition and parent layers of the bimetallic sheets). The microstructure and mechanical properties of the welded joint were investigated. The results showed that in the thickness direction, microstructure and mechanical properties of the welded joint exhibited obvious inhomogeneity. The microstructures of parent filler layers consisted of acicular ferrite, widmanstatten ferrite, and a small amount of blocky ferrite. The microstructure of the transition layer and flyer layer consisted of both austenite and ferrite structures; however, the transition layer of weld had a higher volume fraction of austenite. The results of the microhardness test showed that in both weld metal (WM) and heat-affected zone (HAZ) of the parent filler layers, the average hardness decreased with the increasing (from parent filler layer 1 to parent filler layer 3) welding heat input. The results of hardness test also indicated that the hardness of the WM and the HAZ for the flyer and transition layers was equivalent. The tensile test combined with Digital Specklegram Processing Technology demonstrated that the fracturing of the welded joint started at the HAZ of the flyer, and then the fracture grew toward the base metal of the parent flyer near the parent HAZ. The stratified impact test at -5 °C showed that the WM and HAZ of the flyer exhibited lower impact toughness, and the fracture mode was ductile and brittle mixed fracture.

  14. Web API Fragility: How Robust is Your Web API Client

    NARCIS (Netherlands)

    Espinha, T.; Zaidman, A.; Gross, H.G.

    2014-01-01

    Web APIs provide a systematic and extensible approach for application-to-application interaction. A large number of mobile applications makes use of web APIs to integrate services into apps. Each Web API’s evolution pace is determined by their respective developer and mobile application developers a

  15. Learning Bing maps API

    CERN Document Server

    Sinani, Artan

    2013-01-01

    This is a practical, hands-on guide with illustrative examples, which will help you explore the vast universe of Bing maps.If you are a developer who wants to learn how to exploit the numerous features of Bing Maps then this book is ideal for you. It can also be useful for more experienced developers who wish to explore other areas of the APIs. It is assumed that you have some knowledge of JavaScript, HTML, and CSS. For some chapters a working knowledge of .Net and Visual Studio is also needed.

  16. AUTOMATED API TESTING APPROACH

    Directory of Open Access Journals (Sweden)

    SUNIL L. BANGARE

    2012-02-01

    Full Text Available Software testing is an investigation conducted to provide stakeholders with information about the quality of the product or service under test. With the help of software testing we can verify or validate the software product. Normally testing will be done after development of software but we can perform the software testing at the time of development process also. This paper will give you a brief introduction about Automated API Testing Tool. This tool of testing will reduce lots of headache after the whole development of software. It saves time as well as money. Such type of testing is helpful in the Industries & Colleges also.

  17. Contracting the Facebook API

    OpenAIRE

    2010-01-01

    In recent years, there has been an explosive growth in the popularity of online social networks such as Facebook. In a new twist, third party developers are now able to create their own web applications which plug into Facebook and work with Facebook's "social" data, enabling the entire Facebook user base of more than 400 million active users to use such applications. These client applications can contain subtle errors that can be hard to debug if they misuse the Facebook API. In this paper w...

  18. H2S Stress Corrosion Tests of Welded Joint for X65 Pipeline Steel and Finite Element Numerical Analysis of Crack Tip

    Institute of Scientific and Technical Information of China (English)

    金晓军; 霍立兴; 张玉凤; 白秉仁; 李小巍; 曹军

    2003-01-01

    The microstructure of welded joint is surveyed and the mechanical properties of X65 pipeline steel are studied in this paper, which provides experimental basis of performance effect on stress corrosion. H2S stress corrosion cracking (SCC) tests on the steel are carried out in the environment based on NACE TM-01-77 solution. The threshold stress intensity factor and crack propagation velocity for base metal and HAZ are obtained. The susceptibility of welded joint for X65 pipeline steel to H2S stress corrosion cracking is investigated. The programming package ANSYS of finite element model (FEM) is used to perform the three-dimensional elastic-plastic finite element analysis of WOL specimens. Stress field and concentration of hydrogen distribution property of the crack tip are obtained.

  19. Twitter manager GO API intended for GNU Social API

    OpenAIRE

    Janiga, Jaroslav

    2015-01-01

    The bachelor’s thesis had two goals. The first one was to create API for GO programming language that communicates with GNU Social API. The second one was to create an application that uses the mentioned API. The main purpose of creating the application was to reduce the time spent with the login and logout of the accounts by the members in the white team. The application is intended for training purposes in JYVSECTEC project at JAMK University of Applied Sciences. JYVSECTEC sta...

  20. A Review on Genomics APIs

    Directory of Open Access Journals (Sweden)

    Rajeswari Swaminathan

    2016-01-01

    Full Text Available The constant improvement and falling prices of whole human genome Next Generation Sequencing (NGS has resulted in rapid adoption of genomic information at both clinics and research institutions. Considered together, the complexity of genomics data, due to its large volume and diversity along with the need for genomic data sharing, has resulted in the creation of Application Programming Interface (API for secure, modular, interoperable access to genomic data from different applications, platforms, and even organizations. The Genomics APIs are a set of special protocols that assist software developers in dealing with multiple genomic data sources for building seamless, interoperable applications leading to the advancement of both genomic and clinical research. These APIs help define a standard for retrieval of genomic data from multiple sources as well as to better package genomic information for integration with Electronic Health Records. This review covers three currently available Genomics APIs: a Google Genomics, b SMART Genomics, and c 23andMe. The functionalities, reference implementations (if available and authentication protocols of each API are reviewed. A comparative analysis of the different features across the three APIs is provided in the Discussion section. Though Genomics APIs are still under active development and have yet to reach widespread adoption, they hold the promise to make building of complicated genomics applications easier with downstream constructive effects on healthcare.

  1. Intro to the Zotero API

    Directory of Open Access Journals (Sweden)

    Amanda Morton

    2013-04-01

    Full Text Available In this lesson, you’ll learn how to use python with the Zotero API to interact with your Zotero library. The Zotero API is a powerful interface that would allow you to build a complete Zotero client from scratch if you so desired. But like most APIs, it works in small, discrete steps, so we have to build our way up to the complicated requests we might want to use to access our Zotero libraries. But this incremental building gives us plenty of time to learn as we go along.

  2. ALMACÉN DE CARBONO EN SISTEMAS AGROFORESTALES CON CAFÉ

    OpenAIRE

    William Espinoza-Domínguez; L. Krishnamurthy; Antonio Vázquez-Alarcón; Antonio Torres- Rivera

    2012-01-01

    El presente estudio se realizó con el objetivo de estimar el almacén de carbono en sistemas agroforestales (SAF) con base en café en la región de Huatusco, zona de mayor producción de café (Coffea arabiga L.) en el estado de Veracruz, México, a fin de obtener información cuantitativa sobre el potencial de mitigación de carbono en los SAF de la región. Para ello, se estimaron los reservorios de carbono en biomasa vegetal y la materia orgánica edáfica existentes en sistemas agroforestales de ca...

  3. Maximização do teor de carbono fixo em biocarvão aplicado ao sequestro de carbono

    Directory of Open Access Journals (Sweden)

    Alessandra L. da Róz

    2015-08-01

    Full Text Available RESUMOA emissão de dióxido de carbono é, atualmente, a principal causa do aquecimento global, devido ao efeito estufa. Ao redor do planeta pesquisadores têm-se esforçado na busca de soluções viáveis para o problema; com isto, o biocarvão está entre as mais recentes propostas de mitigação das mudanças climáticas em razão da sua simplicidade e eficiência. Desta forma, este trabalho teve, por objetivo, maximizar o teor de carbono fixo na produção de biocarvão. Para isso, analisaram-se sete tratamentos, temperaturas de pirólise: 200, 250, 300, 350, 400, 450 e 500 °C. A partir do rendimento gravimétrico de produção e do teor de carbono fixo calcularam-se os respectivos fatores de rendimento gravimétrico para cada tratamento, os quais indicam em qual temperatura se tem a maior quantidade de carbono fixo em função do biocarvão produzido. A pirólise com temperatura máxima de 300 °C indicou o maior fator de rendimento gravimétrico, atingindo 0,22672 C/biocarvão.

  4. Automated Ply Inspection (API) for AFP Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Automated Ply Inspection (API) system autonomously inspects layups created by high speed automated fiber placement (AFP) machines. API comprises a high accuracy...

  5. USAJOBS Job Opportunity Announcements (JOA) SOAP API

    Data.gov (United States)

    Office of Personnel Management — The purpose of the SOAP based API is to provide the full Federal Job Opportunity Announcement (JOA) content to the consumer. It is anticipated that this API will be...

  6. USAJOBS Job Opportunity Announcements (JOA) REST API

    Data.gov (United States)

    Office of Personnel Management — This REST-based API is designed to support lightweight Federal Job Opportunity Announcement (JOA) content consumption by consumers. It is anticipated that this API...

  7. Dielectric properties of PLZT-x/65/35 (2≤x≤13 under mechanical stress, electric field and temperature loading

    Directory of Open Access Journals (Sweden)

    K. Pytel

    2013-01-01

    Full Text Available We investigated the effect of uniaxial pressure (0÷1000 bars applied parallely to the ac electric field on dielectric properties of PLZT-x/65/35 (2≤x≤13 ceramics. There was revealed a significant effect of the external stress on these properties. The application of uniaxial pressure leads to the change of the peak intensity of the electric permittivity (ϵ, of the frequency dispersion as well as of the dielectric hysteresis. The peak intensity ϵ becomes diffused/sharpened and shifts to a higher/lower temperatures with increasing the pressure. It was concluded that the application of uniaxial pressure induces similar effects as increasing the Ti ion concentration in PZT system. We interpreted our results based on the domain switching processes under the action of combined electromechanical loading.

  8. X65钢在含超临界CO2的NaCl溶液中腐蚀机制的讨论%CORROSION MECHANISM DISCUSSION OF X65 STEEL IN NaCl SOLUTION SATURATED WITH SUPERCRITICAL CO2

    Institute of Scientific and Technical Information of China (English)

    魏亮; 庞晓露; 高克玮

    2015-01-01

    利用高温高压反应釜研究了X65管线钢在含有超临界CO2(supercritical CO.SC CO2)的3.5%NaC1溶液、去离子水以及溶解有NaC1溶液的超临界CO2相中的腐蚀行为.结果表明,C1-的存在导致X65钢在含有饱和SC CO2的NaC1溶液中的腐蚀速率显著升高,腐蚀产物膜的晶粒形貌发生改变.X65钢在超临界CO2相中的腐蚀速率远远低于在NaCl溶液中的腐蚀速率,但出现局部腐蚀.X65钢在含有SC CO2的NaC1溶液中的腐蚀分为3个阶段:第一个阶段为基体快速溶解阶段,表面没有FeCO3生成;第二阶段为FeCO3开始沉积阶段,形成的FeCO3腐蚀产物膜不完整,增大了阴极还原反应面积,导致腐蚀加速;第三阶段为腐蚀产物膜保护阶段,形成的腐蚀产物膜致密性逐渐提高,保护性好,但C1-仍然可以穿过腐蚀产物膜到达膜基界面,从而加速钢的腐蚀.建立了普通管线钢在含C1-溶液中的超临界CO2腐蚀模型.

  9. Automated information extraction from web APIs documentation

    OpenAIRE

    Ly, Papa Alioune; Pedrinaci, Carlos; Domingue, John

    2012-01-01

    A fundamental characteristic of Web APIs is the fact that, de facto, providers hardly follow any standard practices while implementing, publishing, and documenting their APIs. As a consequence, the discovery and use of these services by third parties is significantly hampered. In order to achieve further automation while exploiting Web APIs we present an approach for automatically extracting relevant technical information from the Web pages documenting them. In particular we have devised two ...

  10. Accessing Inaccessible Android APIs: An Empirical Study

    OpenAIRE

    Li, LI; Bissyande, Tegawendé François D Assise; Le Traon, Yves; Klein, Jacques

    2016-01-01

    As Android becomes a de-facto choice of development platform for mobile apps, developers extensively leverage its accompanying Software Development Kit to quickly build their apps. This SDK comes with a set of APIs which developers may find limited in comparison to what system apps can do or what framework developers are preparing to harness capabilities of new generation devices. Thus, developers may attempt to explore in advance the normally “inaccessible” APIs for building unique API-based...

  11. BusinessUSA Resource Access API

    Data.gov (United States)

    General Services Administration — BusinessUSA connects businesses to government services and information. The API provides access to resource abstracts including programs, services, data, events, and...

  12. AKTIVITAS ANTIOKSIDAN DAN EFEK HEPATOPROTEKTIF DAUN BAKAU API-API PUTIH

    Directory of Open Access Journals (Sweden)

    safrina dyah hardiningtyas

    2014-07-01

    Full Text Available Penelitian ini bertujuan untuk mendapatkan ekstrak kasar daun api-api putih yang memiliki aktivitas antioksidan terbaik, menentukan kandungan fitokimia dan efek Hepatoprotektif ekstrak kasar yang dipilih secara in vivo. Daun api-api putih diekstrak menggunakan tiga jenis pelarut, yakni metanol, etil asetat dan n-heksana. Dalam uji in vivo dilakukan evaluasi terhadap kadar malondialdehid (MDA, enzim aspartat transaminase (AST, enzim alanin transaminase (ALT, dan histopatologi. Hasil penelitian menunjukkan bahwa ekstraksi daun api-api putih dengan pelarut etil asetat menghasilkan aktivitas antioksidan terbaik dengan kandungan fitokimia terdiri dari flavonoid dan steroid/triterpenoid. Pemberian ekstrak etil asetat daun api-api putih pada tikus yang telah diinduksi CCl4 dapat menormalkan berbagai parameter biokimia stres oksidatif (kadar MDA, AST, dan ALT dibandingkan dengan standar Silymarin. Ekstrak daun api-api putih berpotensi untuk melindungi hati tikus dari kerusakan oksidatif yang diinduksi CCl4. Efek Hepatoprotektif ekstrak daun api-api putih berkorelasi dengan aktivitas antioksidannya.Kata kunci: antioksidan, Avicennia marina, ekstrak, hepatoprotektor

  13. Evidence of Apis cerana Sacbrood virus Infection in Apis mellifera

    Science.gov (United States)

    Gong, Hong-Ri; Chen, Xiu-Xian; Chen, Yan Ping; Hu, Fu-Liang; Zhang, Jiang-Lin; Lin, Zhe-Guang; Yu, Ji-Wei

    2016-01-01

    Sacbrood virus (SBV) is one of the most destructive viruses in the Asian honeybee Apis cerana but is much less destructive in Apis mellifera. In previous studies, SBV isolates infecting A. cerana (AcSBV) and SBV isolates infecting A. mellifera (AmSBV) were identified as different serotypes, suggesting a species barrier in SBV infection. In order to investigate this species isolation, we examined the presence of SBV infection in 318 A. mellifera colonies and 64 A. cerana colonies, and we identified the genotypes of SBV isolates. We also performed artificial infection experiments under both laboratory and field conditions. The results showed that 38 A. mellifera colonies and 37 A. cerana colonies were positive for SBV infection. Phylogenetic analysis based on RNA-dependent RNA polymerase (RdRp) gene sequences indicated that A. cerana isolates and most A. mellifera isolates formed two distinct clades but two strains isolated from A. mellifera were clustered with the A. cerana isolates. In the artificial-infection experiments, AcSBV negative-strand RNA could be detected in both adult bees and larvae of A. mellifera, although there were no obvious signs of the disease, demonstrating the replication of AcSBV in A. mellifera. Our results suggest that AcSBV is able to infect A. mellifera colonies with low prevalence (0.63% in this study) and pathogenicity. This work will help explain the different susceptibilities of A. cerana and A. mellifera to sacbrood disease and is potentially useful for guiding beekeeping practices. PMID:26801569

  14. Para onde vamos com o sequestro de carbono? A rede sociotécnica do carbono assimilado por manguezais

    OpenAIRE

    Viviane Fernandez

    2015-01-01

    O presente estudo defende a tese de que o desenvolvimento da capacidade de abordar a realidade de forma integrada, através de exercícios interdisciplinares e/ou transdisciplinares, torna a ciência mais interessante, completa e, ao mesmo tempo, mais comum. Para alcançá-la, em lugar de abordar o "estoque e sequestro de carbono em manguezais" como um objeto de estudo natural e pertinente às disciplinas Oceanografia, Ecologia, Engenharia Florestal e outras do mesmo campo, optou-se ...

  15. Validation of the Parlay API through prototyping

    NARCIS (Netherlands)

    Hellenthal, J.W.; Planken, F.J.M.; Wegdam, M.

    2001-01-01

    The desire within the telecommunications world for new and faster business growth has been a major drive towards the development of open network API. Over the past 7 years several (semi) standardization groups have announced work on network API, including TINA-C, JAIN, IEEE P1520, INforum, 3GPP, JAI

  16. Modelo global do ciclo biogeoquímico do carbono-enxofre

    OpenAIRE

    Cleyde Corrêa Roncaratti

    1995-01-01

    Os dois ciclos mais importantes nas reações de oxi-redução, no ambiente de superfície, são o do carbono e o do enxofre que fazem parte de um sistema maior que compreende a atmosfera, biosfera e litosfera sedimentar. Levando isso em conta, partimos de um modelo de simulação numérica do ciclo biogeoquímico global, para investigar o papel do sistema carbono-oxigênio-enxofre. A modelagem se baseia em estudos nos quais o ciclo do carbono é conjugado com o ciclo do enxofre, elaborada a partir dos p...

  17. Evidence of Apis cerana Sacbrood virus Infection in Apis mellifera.

    Science.gov (United States)

    Gong, Hong-Ri; Chen, Xiu-Xian; Chen, Yan Ping; Hu, Fu-Liang; Zhang, Jiang-Lin; Lin, Zhe-Guang; Yu, Ji-Wei; Zheng, Huo-Qing

    2016-04-01

    Sacbrood virus(SBV) is one of the most destructive viruses in the Asian honeybee Apis cerana but is much less destructive in Apis mellifera In previous studies, SBV isolates infecting A. cerana(AcSBV) and SBV isolates infecting A. mellifera(AmSBV) were identified as different serotypes, suggesting a species barrier in SBV infection. In order to investigate this species isolation, we examined the presence of SBV infection in 318A. mellifera colonies and 64A. cerana colonies, and we identified the genotypes of SBV isolates. We also performed artificial infection experiments under both laboratory and field conditions. The results showed that 38A. mellifera colonies and 37A. cerana colonies were positive for SBV infection. Phylogenetic analysis based on RNA-dependent RNA polymerase (RdRp) gene sequences indicated that A. cerana isolates and most A. mellifera isolates formed two distinct clades but two strains isolated fromA. mellifera were clustered with theA. cerana isolates. In the artificial-infection experiments, AcSBV negative-strand RNA could be detected in both adult bees and larvae ofA. mellifera, although there were no obvious signs of the disease, demonstrating the replication of AcSBV inA. mellifera Our results suggest that AcSBV is able to infectA. melliferacolonies with low prevalence (0.63% in this study) and pathogenicity. This work will help explain the different susceptibilities ofA. cerana and A. melliferato sacbrood disease and is potentially useful for guiding beekeeping practices.

  18. How do developers use APIs? A case study in concurrency

    NARCIS (Netherlands)

    Blom, Stefan; Kiniry, Joseph; Huisman, Marieke

    2013-01-01

    With the omnipresent usage of APIs in software development, it has become important to analyse how the routines and functionalities of APIs are actually used. This information is in particular useful for API developers, to make decisions about future updates of the API. However, also for developers

  19. Web API Growing Pains: Loosely Coupled yet Strongly Tied

    NARCIS (Netherlands)

    Espinha, T.; Zaidman, A.; Gross, H.G.

    2014-01-01

    Web APIs provide a systematic and extensible approach for application-toapplication interaction. Developers using web APIs are forced to accompany the API providers in their software evolution tasks. In order to understand the distress caused by this imposition on web API client developers we perfor

  20. Analysis and Applications API eBay

    OpenAIRE

    ŠIK, Martin

    2013-01-01

    The subject of this bachelor thesis "Analysis and Applications API eBay" is to create application based on the use of Application Programming Interface (API), released by eBay. The theoretical part is focused on explaining the fundamental issue of Internet auctions, e-commmerce, comparsion of auction portals and term "trust" as a key attribute of e-commerce. The practical part is based on analyse of principles and instruments of eBay API and create an application based on this interface. The ...

  1. DySectAPI: Scalable Prescriptive Debugging

    DEFF Research Database (Denmark)

    Jensen, Nicklas Bo; Karlsson, Sven; Quarfot Nielsen, Niklas;

    We present the DySectAPI, a tool that allow users to construct probe trees for automatic, event-driven debugging at scale. The traditional, interactive debugging model, whereby users manually step through and inspect their application, does not scale well even for current supercomputers. While...... lightweight debugging models scale well, they can currently only debug a subset of bug classes. DySectAPI fills the gap between these two approaches with a novel user-guided approach. Using both experimental results and analytical modeling we show how DySectAPI scales and can run with a low overhead...

  2. El lago Chinchaycocha en el mercado de bonos de carbono

    Directory of Open Access Journals (Sweden)

    Wilfredo Bulege Gutiérrez

    2012-12-01

    Full Text Available El cambio climático como fenómeno global preocupa a todo el mundo y se manifiesta en lo cotidiano a través de diversos desórdenes del clima. El Panel Intergubernamental de Cambio Climático (IPCC, en su cuarto informe de evaluación presentado el 2007, y la Organización Mundial de Meteorología (OMM han establecido que desde el 2001 la temperatura media global en el planeta registra el nivel de aumento más alto de nuestra historia. A este ritmo, y por lo difícil que resulta encontrar una solución aun en el mediano plazo, todo indica que el 2013 no será la excepción. Las causas del cambio climático son atribuidas a factores naturales pero también antropogénicos; existe ya consenso respecto a la influencia de los gases de efecto invernadero (GEI, sobre todo el dióxido de carbono (CO2 en este proceso acelerado de calentamiento del planeta. Esta crisis del clima, como una forma de ser enfrentada, hoy está obligando a los países a promover proyectos que reduzcan las emisiones de GEI y permitan el almacenamiento de carbono. Uno de los mecanismos internacionales establecidos para concretar este objetivo son los bonos de carbono, iniciativa dispuesta por el Protocolo de Kioto, acuerdo jurídicamente vinculante firmado en 1997 y en vigor desde el 2005. Expiró el año pasado, pero la histórica Conferencia de Doha, Catar, decidió en diciembre último prorrogar la vigencia del tratado hasta el 2020. El protocolo, en su primera fase, exige a las grandes potencias reducir durante el período 2008-2012 la emisión de gases en un 5,2% por debajo del nivel de 1990. Lo interesante es que las empresas de tales potencias, para cumplir esta obligación, pueden hacerlo en cualquier lugar o comprar bonos de carbono de países que superen las metas exigidas. La emisión de estos bonos es, después de todo, una iniciativa de descontaminación, que permite que los países industrializados sigan con sus prácticas contaminantes, en tanto

  3. Real World Uses For Nagios APIs

    Science.gov (United States)

    Singh, Janice

    2014-01-01

    This presentation describes the Nagios 4 APIs and how the NASA Advanced Supercomputing at Ames Research Center is employing them to upgrade its graphical status display (the HUD) and explain why it's worth trying to use them yourselves.

  4. BeXRB Monitor Data API

    Data.gov (United States)

    National Aeronautics and Space Administration — A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples. This is a monitor using data from Swift/BAT, MAXI and Fermi/GBM...

  5. ChemSpell Web Service API

    Data.gov (United States)

    U.S. Department of Health & Human Services — The ChemSpell Web Service API provides chemical name spell checking and chemical name synonym look-up. ChemSpell contains more than 1.3 million chemical names...

  6. System for Award Management (SAM) API

    Data.gov (United States)

    General Services Administration — The SAM API is a RESTful method of retrieving public information about the businesses, organizations, or individuals (referred to as entities) within the SAM entity...

  7. Catalizadores Pd/líquido iónico soportados en materiales de carbono: diseño, preparación y aplicación en reacciones de formación de enlace carbono-carbono

    OpenAIRE

    Menéndez Vázquez, Carmen

    2012-01-01

    El presente trabajo consiste en la preparación y evaluación de la actividad de los catalizadores soportados sobre material de carbono y el estudio de su reutilización. A su vez, se lleva a cabo un estudio de la posible influencia que pueda tener el propio diseño del catalizador sobre el rendimiento del mismo.

  8. Compuestos del ciclo del carbono en la zona litoral del municipio Playa, Ciudad de la Habana, Cuba.

    OpenAIRE

    Montalvo, J. F.; García, I.; Esponda, S.C.; Cesar, M.E.; Alburquerque, O.

    2009-01-01

    Se realizaron cinco muestreos entre enero de 2007 y junio de 2008 a la zona costera del municipio Playa, con el fin de evaluar los contenidos de los compuestos del ciclo del carbono. Los parámetros estudiados en la matriz agua fueron carbón orgánico, pH, alcalinidad total, alcalinidad al carbonato, dióxido de carbono total, dióxido de carbono libre, presión parcial de CO2, y contenidos de bicarbonato y carbonato. Los compuestos de carbono orgánico e inorgánico tuvieron una distribución muy he...

  9. APIs and Researchers: The Emperor's New Clothes?

    Directory of Open Access Journals (Sweden)

    Jennifer Edmond

    2015-02-01

    Full Text Available As part of the Europeana Cloud (eCloud project, Trinity College Dublin investigated best practice in the use of web services, such as APIs, for accessing large data sets from cultural heritage collections. This research looked into the provision and use of APIs, and moreover, whether or not more customised programmatic access to datasets is what researchers want or need. In order to understand whether current patterns of API usage reflect a skills gap on the part of researchers or a mismatch of tool to purpose, we looked not only at the creators and developer/users of APIs, but also at humanists already re-using big data; approaches in cultural heritage institutions and other research infrastructures to bring API use to non-technical audiences; and the kinds of training and other support services available or emerging within the data-intensive humanities research lifecycle. We conducted both desk research and a series of 11 interviews with figures working as researchers, developers or data providers, including figures from both the API development and the data usage communities. This research, conducted under the eCloud project and supported by the European Commission’s ICT Policy and Support Programme (Grant number 325091, was begun in March 2014 and is now in its concluding validation stage. The results of the research are not yet finalised, but the contribution is already emerging of this work to the debate about APIs being either the way forward for digital cultural heritage collections, or the Emperor’s New Clothes (or maybe a bit of both.

  10. Comparative Foraging Behavior of Apis Cerana F. and Apis Mellifera L. in Rapeseed under Cage Condition in Chitwan, Nepal

    Directory of Open Access Journals (Sweden)

    Rameshwor Pudasaini

    2014-12-01

    Full Text Available An experiment was conducted to determine the foraging behavior of Apis mellifera L. and Apis cerana F. in rapeseed under cage condition in Chitwan, Nepal during 2012-2013. This experiment showed that Apis cerana F. foraged extra 42 minute per day as compared to Apis mellifera L. Apis cerana F. were more attracted to nectar, whereas Apis mellifera L. were more attracted to pollen collection throughout the day. The activities, in into hives and out from hives, for both species were recorded more at 2:00 pm and least at 8:00 am. The highest in-out were observed at 2:00 pm on both species as Apis mellifera L. 44.33 bees entered into hives and 49.66 bees went out of hives, whereas lower number of Apis cerana F. 43.66 bees entered into hives and 48.16 bees were out of hives. Apis mellifera L. collect 1.22:1 and 0.41:1 pollen nectar ratio at 10:00 am and 4:00 am whereas at same hours Apis cerana collect 1.16:1 and 0.30:1 pollen nectar ratio. Apis cerana F. foraged significantly higher number of rapeseed flowers and plants as compared to Apis mellifera L. under caged condition. It shows that Apis cerana F. was more efficient pollinator as compared to Apis mellifera L. under caged condition.

  11. Development of API 5L X70 and X80 in the Brazilian Vallourec and Mannesmann Tubes industry; Desenvolvimento de acos API 5L X70 e X80 na Vallourec e Mannesmann Tubes

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Julio M. Silveira e; Carvalho, Ricardo N. de [Vallourec and Mannesmann Tubes - V e M do Brasil, Belo Horizonte, MG (Brazil)

    2000-07-01

    The demand for seamless pipes with resistance higher than those for API 5L X60 and X65 grades has increased in the last years. They are traditionally used up to now for applications on rigid risers for production and exportation and line pipes for oil and gas. In the case of seamless pipes, the great challenge is to fulfill the requirements of mechanical properties for X70 and X80 grades, quenched and tempered, with values of carbon equivalent low enough to assure a good weldability. This paper presents the results obtained by Vallourec and Mannesmann Tubes - V and M do Brazil on producing seamless pipes of X70 and X80 API grades, with outside diameter lower than 8 5/8{sup (} 219,1 mm ) and wall thickness up to 0,562{sup (} 14,3 mm ). Results of tensile, Charpy notch impact resistance and hardness tests are shown. Hydrogen-Induced and Environmental Cracking tests were also carried out, since for some applications is required a good resistance to these kinds of embrittlement mechanisms. The mechanical properties, microstructure and physical characteristics of welded joints were also evaluated. The results obtained up to now are quite promising, showing good suitability to the aimed final applications. (author)

  12. CALIBRATION, OPTIMIZATION, AND SENSITIVITY AND UNCERTAINTY ALGORITHMS APPLICATION PROGRAMMING INTERFACE (COSU-API)

    Science.gov (United States)

    The Application Programming Interface (API) for Uncertainty Analysis, Sensitivity Analysis, and Parameter Estimation (UA/SA/PE API) tool development, here fore referred to as the Calibration, Optimization, and Sensitivity and Uncertainty Algorithms API (COSU-API), was initially d...

  13. Advanced API security securing APIs with OAuth 2.0, OpenID Connect, JWS, and JWE

    CERN Document Server

    Siriwardena, Prabath

    2014-01-01

    Advanced API Security is a complete reference to the next wave of challenges in enterprise security--securing public and private APIs. API adoption in both consumer and enterprises has gone beyond predictions. It has become the 'coolest' way of exposing business functionalities to the outside world. Both your public and private APIs, need to be protected, monitored and managed. Security is not an afterthought, but API security has evolved a lot in last five years. The growth of standards, out there, has been exponential. That's where AdvancedAPI Security comes in--to wade through the weeds

  14. Comparative virulence and competition between Nosema apis and Nosema ceranae in honey bees (Apis mellifera).

    Science.gov (United States)

    Milbrath, Meghan O; van Tran, Toan; Huang, Wei-Fong; Solter, Leellen F; Tarpy, David R; Lawrence, Frank; Huang, Zachary Y

    2015-02-01

    Honey bees (Apis mellifera) are infected by two species of microsporidia: Nosema apis and Nosemaceranae. Epidemiological evidence indicates that N. ceranae may be replacing N. apis globally in A. mellifera populations, suggesting a potential competitive advantage of N. ceranae. Mixed infections of the two species occur, and little is known about the interactions among the host and the two pathogens that have allowed N. ceranae to become dominant in most geographical areas. We demonstrated that mixed Nosema species infections negatively affected honey bee survival (median survival=15-17days) more than single species infections (median survival=21days and 20days for N. apis and N. ceranae, respectively), with median survival of control bees of 27days. We found similar rates of infection (percentage of bees with active infections after inoculation) for both species in mixed infections, with N. apis having a slightly higher rate (91% compared to 86% for N. ceranae). We observed slightly higher spore counts in bees infected with N. ceranae than in bees infected with N. apis in single microsporidia infections, especially at the midpoint of infection (day 10). Bees with mixed infections of both species had higher spore counts than bees with single infections, but spore counts in mixed infections were highly variable. We did not see a competitive advantage for N. ceranae in mixed infections; N. apis spore counts were either higher or counts were similar for both species and more N. apis spores were produced in 62% of bees inoculated with equal dosages of the two microsporidian species. N. ceranae does not, therefore, appear to have a strong within-host advantage for either infectivity or spore growth, suggesting that direct competition in these worker bee mid-guts is not responsible for its apparent replacement of N. apis.

  15. Unified Medical Language System Terminology Services (UTS) API

    Data.gov (United States)

    U.S. Department of Health & Human Services — The UTS API is intended for application developers to perform Web service calls and retrieve UMLS data within their own applications. The UTS API provides the...

  16. MODAPS Web Services API for LANCE-MODIS

    Data.gov (United States)

    National Aeronautics and Space Administration — MODAPS Web Services API for LANCE-MODIS. This Application Programming Interface (API) encompasses a library of functions that provides programmatic data access to...

  17. Comparing Speech Recognition Systems (Microsoft API, Google API And CMU Sphinx

    Directory of Open Access Journals (Sweden)

    Veton Këpuska

    2017-03-01

    Full Text Available The idea of this paper is to design a tool that will be used to test and compare commercial speech recognition systems, such as Microsoft Speech API and Google Speech API, with open-source speech recognition systems such as Sphinx-4. The best way to compare automatic speech recognition systems in different environments is by using some audio recordings that were selected from different sources and calculating the word error rate (WER. Although the WER of the three aforementioned systems were acceptable, it was observed that the Google API is superior.

  18. Pro REST API development with nodejs

    CERN Document Server

    Doglio, Fernando

    2015-01-01

    Pro REST API Development with Node.js is your guide to managing and understanding the full capabilities of successful REST development. API design is a hot topic in the programming world, but not many resources exist for developers to really understand how you can leverage the advantages. This book will provide a brief background on REST and the tools it provides (well known and not so well known). Understand how there is more to REST than just JSON and URLs. You will then cover and compare the maintained modules currently available in the npm community, including Express, Restify, Vatican,

  19. Crecimiento de nanotubos de carbono sobre materiales de uso convencional en ingeniería

    OpenAIRE

    García Ruiz, Máximo

    2012-01-01

    Los nanotubos de carbono son una forma alotrópica del carbono, como el diamante o el grafito, que, debido a sus propiedades físicas, mecánicas y eléctricas están generando un gran interés de investigación en los últimos años. Típicamente, éstos son formados a partir de precursores tales como el monóxido de carbono, metano, acetileno, tolueno, alcohol, etc. En este proyecto se utilizó tolueno para la síntesis, empleando ferroceno como catalizador. El método utilizado para llevarlo a cabo, fue ...

  20. 47 CFR 61.46 - Adjustments to the API.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Adjustments to the API. 61.46 Section 61.46... Rules for Dominant Carriers § 61.46 Adjustments to the API. (a) Except as provided in paragraphs (d) and... carrier must calculate an API for each affected basket pursuant to the following methodology: APIt =...

  1. Dinámica del carbono (almacenes y flujos) en manglares de México

    OpenAIRE

    2016-01-01

    La cobertura de los manglares de México los coloca en cuarto lugar a nivel mundial. Se reconocen sus múltiples servicios ecosistémicos, pero también altas tasas de deforestación. Evaluaciones en otras partes del mundo destacan el papel de los manglares en el ciclo del carbono, principalmente como almacenes de carbono orgánico (Corg) en los sedimentos y exportadores de Corg disuelto y particulado. Para estimar la contribución de los manglares, a escala local, regional y de país, en estrategias...

  2. Nanomateriales de carbono, síntesis, funcionalización y aplicaciones

    OpenAIRE

    González Velázquez, Viviana Jehová

    2016-01-01

    Mención Internacional en el título de doctor La presente tesis trata acerca del estudio y la búsqueda de aplicaciones de nanomateriales de carbono, principalmente enfocándonos en nanotubos de carbono y grafeno oxidado. La razón por la cual se eligieron estos nanomateriales es debido a su gran versatilidad, a sus excelentes propiedades tanto eléctricas, mecánicas, su gran aspecto superficial que en si engloban a todos estos materiales, haciéndolos candidatos para la era del postsilicio,...

  3. Standard methods for Apis mellifera propolis research

    Science.gov (United States)

    Propolis is one of the most fascinating honey bee (Apis mellifera L.) products. It is a plant derived product that bees produce from resins that they collect from different plant organs and with which they mix beeswax. Propolis is a building material and a protective agent in the beehive. It also pl...

  4. The Apis mellifera filamentous virus genome

    Science.gov (United States)

    A complete reference genome of the Apis mellifera Filamentous virus (AmFV) was determined using Illumina Hiseq sequencing. The AmFV genome is a double strand DNA molecule of approximately 498’500 nucleotides with a GC content of 50.8%. It encompasses 251 non overlapping open reading frames (ORFs), e...

  5. Integrated platform and API for electrophysiological data.

    Science.gov (United States)

    Sobolev, Andrey; Stoewer, Adrian; Leonhardt, Aljoscha; Rautenberg, Philipp L; Kellner, Christian J; Garbers, Christian; Wachtler, Thomas

    2014-01-01

    Recent advancements in technology and methodology have led to growing amounts of increasingly complex neuroscience data recorded from various species, modalities, and levels of study. The rapid data growth has made efficient data access and flexible, machine-readable data annotation a crucial requisite for neuroscientists. Clear and consistent annotation and organization of data is not only an important ingredient for reproducibility of results and re-use of data, but also essential for collaborative research and data sharing. In particular, efficient data management and interoperability requires a unified approach that integrates data and metadata and provides a common way of accessing this information. In this paper we describe GNData, a data management platform for neurophysiological data. GNData provides a storage system based on a data representation that is suitable to organize data and metadata from any electrophysiological experiment, with a functionality exposed via a common application programming interface (API). Data representation and API structure are compatible with existing approaches for data and metadata representation in neurophysiology. The API implementation is based on the Representational State Transfer (REST) pattern, which enables data access integration in software applications and facilitates the development of tools that communicate with the service. Client libraries that interact with the API provide direct data access from computing environments like Matlab or Python, enabling integration of data management into the scientist's experimental or analysis routines.

  6. DySectAPI: Scalable Prescriptive Debugging

    DEFF Research Database (Denmark)

    Jensen, Nicklas Bo; Karlsson, Sven; Quarfot Nielsen, Niklas;

    We present the DySectAPI, a tool that allow users to construct probe trees for automatic, event-driven debugging at scale. The traditional, interactive debugging model, whereby users manually step through and inspect their application, does not scale well even for current supercomputers. While...

  7. How Do Developers Use APIs? A Case Study in Concurrency

    DEFF Research Database (Denmark)

    Blom, Stefan; Kiniry, Joseph; Huisman, Marieke

    2013-01-01

    With the omnipresent usage of APIs in software development, it has become important to analyse how the routines and functionalities of APIs are actually used. This information is in particular useful for API developers, to make decisions about future updates of the API. However, also for developers...... of static analysis and verification tools this information is highly important, because it indicates where and how to put the most efficient effort in annotating APIs, to make them usable for the static analysis and verification tools. This paper presents an analysis of the usage of the routines...

  8. An Implementation Model of Parlay MMCCS API Based on SIP

    Institute of Scientific and Technical Information of China (English)

    GUAN You-qing; SHEN Su-bin

    2006-01-01

    Parlay Multi Media Call Control Services(MMCCS) Application Programming Interfaces (API) based on Session Initiation Protocol (SIP) is essential for the implementation of Parlay Call Control (CC) API. This paper first proposes an implementation model of Parlay MMCCS API based on SIP, then presents a mapping between SIP and MMCCS API as far as methods and parameters are concerned, illustrates corresponding relationships between different components of SIP and MMCCS API by means of an application collaboration diagram, and finally presents an application using Java codes as well as some SIP messages. The application shows that a majority of MMCCS API based on SIP can be implemented and therefore verifies our mapping between MMCCS API and SIP.

  9. Funcionalización de nanomateriales de carbono: Propiedades optoelectrónicas de nanotubos de carbono y aplicaciones de nanopartículas de diamante en catálisis y biocatálisis

    OpenAIRE

    Martín González, Roberto

    2011-01-01

    TÍTULO: Funcionalización de nanomateriales de carbono: Propiedades optoelectrónicas de nanotubos de carbono y aplicaciones de nanopartículas de diamante en catálisis y biocatálisis. INTRODUCCIÓN: En las últimas décadas los nanomateriales han adquirido gran importancia debido a su repercusión en la sociedad. De entre los nanomateriales, aquellos basados en carbono se encuentran entre los más estudiados por sus potenciales aplicaciones. La presente tesis doctoral se ha centrado en la fun...

  10. Nuevos recubrimientos basados en disposiciones ordenadas de nanoparticulas metálicas y nanofibras de carbono

    Directory of Open Access Journals (Sweden)

    A. Berenguer-Murcia

    2010-12-01

    Full Text Available Debido al alto grado de control que permite llevar a cabo, el depósito químico en fase vapor (CVD catalizado es uno de los métodos más atractivos para el crecimiento de nanotubos y nanofibras de carbono sobre distintas superficies.

  11. Population Genetics of Nosema apis and Nosema ceranae: One Host (Apis mellifera) and Two Different Histories.

    Science.gov (United States)

    Maside, Xulio; Gómez-Moracho, Tamara; Jara, Laura; Martín-Hernández, Raquel; De la Rúa, Pilar; Higes, Mariano; Bartolomé, Carolina

    2015-01-01

    Two microsporidians are known to infect honey bees: Nosema apis and Nosema ceranae. Whereas population genetics data for the latter have been released in the last few years, such information is still missing for N. apis. Here we analyze the patterns of nucleotide polymorphism at three single-copy loci (PTP2, PTP3 and RPB1) in a collection of Apis mellifera isolates from all over the world, naturally infected either with N. apis (N = 22) or N. ceranae (N = 23), to provide new insights into the genetic diversity, demography and evolution of N. apis, as well as to compare them with evidence from N. ceranae. Neutral variation in N. apis and N. ceranae is of the order of 1%. This amount of diversity suggests that there is no substantial differentiation between the genetic content of the two nuclei present in these parasites, and evidence for genetic recombination provides a putative mechanism for the flow of genetic information between chromosomes. The analysis of the frequency spectrum of neutral variants reveals a significant surplus of low frequency variants, particularly in N. ceranae, and suggests that the populations of the two pathogens are not in mutation-drift equilibrium and that they have experienced a population expansion. Most of the variation in both species occurs within honey bee colonies (between 62%-90% of the total genetic variance), although in N. apis there is evidence for differentiation between parasites isolated from distinct A. mellifera lineages (20%-34% of the total variance), specifically between those collected from lineages A and C (or M). This scenario is consistent with a long-term host-parasite relationship and contrasts with the lack of differentiation observed among host-lineages in N. ceranae (mellifera worldwide population is a recent event.

  12. Las nanoestructuras de carbono como analitos y herramientas en la química analítica actual

    OpenAIRE

    Suárez González, Beatriz

    2011-01-01

    Esta Tesis Doctoral se ha centrado en: 1,- El desarrollo de procesos analíticos eficaces y fiables que permitan la caracterización y cuantificación de nanoestructuras de carbono (fundamentalmente nanotubos de carbono mono- y multicapa). 2,- Desarrollar nuevas herramientas analíticas basadas en el uso de nanoestructuras de carbonos que comprenden dos aspectos básicos: como material absorbente en procesos de extracción en fase sólida y como fase pseudoestacionaria con vistas al desarrollo de nu...

  13. Aspectos Contábeis dos Créditos de Carbono: Estudo com Autores Nacionais

    Directory of Open Access Journals (Sweden)

    Vanderlei dos Santos

    2013-12-01

    Full Text Available O estudo objetiva verificar o entendimento de autores nacionais no que concerne à classificação, forma de reconhecimento e mensuração das operações com créditos de carbono. O estudo de natureza descritiva foi realizado em 2011, por meio de pesquisa de levantamento ou survey, com abordagem quantitativa. Utilizou-se o questionário como instrumento de coleta de dados, que foi enviado a 23 pesquisadores nacionais que possuem publicação de artigos relacionados à contabilização dos créditos de carbono em periódicos nacionais. Obtiveram-se nove respostas, que constituíram numa amostra por acessibilidade. Para a análise dos dados obtidos optou-se pelo uso da técnica da entropia informacional. Os resultados do estudo mostraram que, quanto à classificação dos créditos de carbono, há um entendimento maior entre os autores de que se trata de ativos especiais e que não podem ser considerados como commodity. Observou-se que não há consenso entre os autores em classificar os créditos de carbono como ativo intangível ou estoque. Deste modo, concluiu-se que ainda existem divergências no entendimento dos autores analisados no que concerne aos aspectos contábeis das operações com créditos de carbono. O artigo contribui principalmente na medida em que busca consolidar diferentes opiniões de autores, que pesquisam sobre a temática, demonstrando aspectos convergentes e divergentes, além de enfatizar lacunas para desenvolver pesquisas futuras.

  14. Experiencias prácticas de aplicación de Huella de Carbono a productos agroalimentarios

    OpenAIRE

    Campus de Excelencia Internacional Agroalimentario (ceiA3)

    2012-01-01

    Experiencias prácticas de aplicación de Huella de Carbono a productos agroalimentarios ¿Cómo ser más competitivo ecoinnovando? La huella ambiental de productos agroalimentarios.Estrategias y resultados

  15. Método de producción de nanotubos de carbono en ausencia de catalizadores metálicos

    OpenAIRE

    2011-01-01

    Hemos patentado una nueva técnica para la síntesis de nanotubos de carbono a partir de la descomposición, de sustancias con contenido en carbono, por un plasma a presión atmosférica, sin la utilización de catalizadores metálicos ni procesos químicos complementarios. . El método de producción consiste en introducir en estado gaseoso la fuente de carbono en una plasma a presión atmosférica. Las partículas del plasma rompen los enlaces de las moléculas de dicha fuente de carbono dando lugar a la...

  16. APIs for QoS configuration in Software Defined Networks

    DEFF Research Database (Denmark)

    Caba, Cosmin Marius; Soler, José

    2015-01-01

    such as configuration of devices, ports, queues, etc. An Application Programming Interface (API) for dynamic configuration of QoS resources in the network devices is implemented herein, by using the capabilities of OVSDB. Further, the paper demonstrates the possibility to create network services with coarse granularity...... on top of the fine granular services exposed by the QoS configuration API at the SDNC. A series of tests emphasize the capabilities and the performance of the implemented QoS configuration API....

  17. Privacy Issues of the W3C Geolocation API

    CERN Document Server

    Doty, Nick; Wilde, Erik

    2010-01-01

    The W3C's Geolocation API may rapidly standardize the transmission of location information on the Web, but, in dealing with such sensitive information, it also raises serious privacy concerns. We analyze the manner and extent to which the current W3C Geolocation API provides mechanisms to support privacy. We propose a privacy framework for the consideration of location information and use it to evaluate the W3C Geolocation API, both the specification and its use in the wild, and recommend some modifications to the API as a result of our analysis.

  18. Integration of Environmental Sensors with BIM: case studies using Arduino, Dynamo, and the Revit API

    Directory of Open Access Journals (Sweden)

    Kensek, K. M.

    2014-12-01

    Full Text Available This paper investigates the feasibility of connecting environmental sensors such as light, humidity, or CO2 receptors to a building information model (BIM. A base case was created in Rhino; using Grasshopper and Firefly, a simple digital model responded to lighting-levels detected by a photoresistor on an Arduino board. The case study was duplicated using Revit Architecture, a popular BIM software, and Dynamo, a visual programming environment, in an innovative application. Another case study followed a similar procedure by implementing the Revit API directly instead of using Dynamo. Then the process was reversed to demonstrate that not only could data could be sent from sensors to change the 3D model, but changes to parameters of a 3D model could effect a physical model through the use of actuators. It is intended that these virtual/physical prototypes could be used as the basis for testing intelligent façade systems before constructing full size mock-ups.Este estudio investiga la posibilidad de conectar sensores ambientales como de luz, humedad, o dióxido de carbono con un modelo de información de un edificio (siglas BIM en inglés. Un caso base fue creado en Rhino; usando Grasshopper and Firefly, donde un simple modelo digital respondió a niveles de luz detectados por un foto resistor en una tarjeta Arduino. El caso de estudio fue duplicado usando Revit Architecture, una herramienta popular en BIM, y Dynamo, un ambiente de programación gráfica, en una creativa aplicación. Un segundo caso de estudio siguió un procedimiento similar implementando Revit API directamente en vez de usar Dynamo. Entonces el proceso fue revertido para demostrar que no solamente la información podría ser enviada desde sensores para cambiar el modelo tridimensional, pero cambios en los parámetros de un modelo tridimensional podrían afectar un modelo físico mediante el uso de actuadores. Se espera que esos modelos virtuales puedan ser usados como base para

  19. Reatividade de intermediários inseridos em matriz de carbono

    OpenAIRE

    2008-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia Química Tem sido proposto que a redução de SO2 em carbonos acontece através de intermediários reativos unidos a matriz de carbono, no qual 2-oxido de 1,2-oxatieteno (ou sultina), e 1,3,2-dioxatiolano são decompostos formando epissulfeto e CO2. A reatividade desses intermediários foi estudada neste trabalho através de várias reações, usando espectros XPS e NMR para po...

  20. Estabelecimento de parâmetros reológicos na obtenção de compósitos carbono/fenólica

    OpenAIRE

    Edson C. Botelho; Scherbakoff,Natália; Mirabel C Rezende

    1999-01-01

    As resinas fenólicas têm sido utilizadas no processamento de compósitos carbono/carbono, produzindo um material intermediário conhecido como compósito carbono/fenólica. O presente trabalho mostra os resultados obtidos de análises reológicas, cromatográficas e por calorimetria exploratória diferencial (DSC) de duas amostras de resinas fenólicas tipo novolaca e uma resol, visando escolher a matéria-prima e os parâmetros mais adequados ao processamento de compósitos carbono/fenólica. Os resultad...

  1. Adaptive runtime for a multiprocessing API

    Energy Technology Data Exchange (ETDEWEB)

    Antao, Samuel F.; Bertolli, Carlo; Eichenberger, Alexandre E.; O' Brien, John K.

    2016-10-11

    A computer-implemented method includes selecting a runtime for executing a program. The runtime includes a first combination of feature implementations, where each feature implementation implements a feature of an application programming interface (API). Execution of the program is monitored, and the execution uses the runtime. Monitor data is generated based on the monitoring. A second combination of feature implementations are selected, by a computer processor, where the selection is based at least in part on the monitor data. The runtime is modified by activating the second combination of feature implementations to replace the first combination of feature implementations.

  2. Adaptive runtime for a multiprocessing API

    Energy Technology Data Exchange (ETDEWEB)

    Antao, Samuel F.; Bertolli, Carlo; Eichenberger, Alexandre E.; O' Brien, John K.

    2016-11-15

    A computer-implemented method includes selecting a runtime for executing a program. The runtime includes a first combination of feature implementations, where each feature implementation implements a feature of an application programming interface (API). Execution of the program is monitored, and the execution uses the runtime. Monitor data is generated based on the monitoring. A second combination of feature implementations are selected, by a computer processor, where the selection is based at least in part on the monitor data. The runtime is modified by activating the second combination of feature implementations to replace the first combination of feature implementations.

  3. Rare royal families in honeybees, Apis mellifera

    Science.gov (United States)

    Moritz, Robin F. A.; Lattorff, H. Michael G.; Neumann, Peter; Kraus, F. Bernhard; Radloff, Sarah E.; Hepburn, H. Randall

    2005-10-01

    The queen is the dominant female in the honeybee colony, Apis mellifera, and controls reproduction. Queen larvae are selected by the workers and are fed a special diet (royal jelly), which determines caste. Because queens mate with many males a large number of subfamilies coexist in the colony. As a consequence, there is a considerable potential for conflict among the subfamilies over queen rearing. Here we show that honeybee queens are not reared at random but are preferentially reared from rare “royal” subfamilies, which have extremely low frequencies in the colony's worker force but a high frequency in the queens reared.

  4. Mutantes de Lactobacilus casei con regulación defectuosa del catabolismo del carbono

    OpenAIRE

    Pérez Martínez, Gaspar; Monedero, Vicente; Deutscher, Josef; Viana, Rosa; Benbadis, Laurent; Pierson, Anne; Faurie, Jean Michel

    2007-01-01

    Utilización de un mutante de L. casei que presenta por lo menos una mutación en el gen ptsI, en la que dicha mutación perjudica la regulación de un mecanismo de represión catabólica por carbono (CCR) que implica la proteína PTS HPr, para la preparación de un producto alimenticio.

  5. Tozaltı Ark Kaynak Yöntemi ile Birleştirilen X60, X65 ve X70 Çeliklerin Kaynak Bölgesinin Etüdü

    OpenAIRE

    Ali Akın Akay, ,; Yakup Kaya; Nizamettin Kahraman

    2013-01-01

    Bu çalışmada, petrol ve doğal gaz hatlarında kullanılan, düşük alaşımlı, ince taneli ve yüksek mukavemetli X60, X65 ve X70 çelikleri, tozaltı ark kaynak yöntemi ile iki farklı tel (S1 ve S2Mo) ve toz (LN761 ve P223) kullanılarak birleştirilmiştir. Kaynaklı birleştirmelere, öncelikle yüzey ve yüzey altı kusurların belirlenebilmesi için tahribatsız muayene yöntemlerinden gözle ve ultrasonik muayeneye teknikleri uygulanmış, sonrasında birleştirmelerin dayanımlarını belirlemek amacıyla, çekme ve ...

  6. Renovação do carbono-13 em figueiras 'Roxo de Valinhos'

    Directory of Open Access Journals (Sweden)

    Andréa Carvalho da Silva

    2011-06-01

    Full Text Available O objetivo do trabalho foi determinar a taxa de renovação do carbono-13 ("turnover", dos diferentes órgãos da figueira 'Roxo de Valinhos'. O experimento foi conduzido no pomar da Faculdade de Ciências Agronômicas, FCA/UNESP, Câmpus de Botucatu-SP. Determinou-se previamente, através das trocas gasosas com um medidor aberto portátil de fotossíntese, IRGA, a principal folha fotossinteticamente ativa. Essa folha foi colocada em uma câmara onde ocorreu a injeção do gás enriquecido. O tempo de enriquecimento da folha foi de 30 minutos. Os tratamentos foram constituídos por sete plantas de figueira, que foram retiradas do solo após: 6; 24; 48; 72; 120; 168 e 360 horas do enriquecimento com 13C, e suas partes seccionadas em: gema apical, folha jovem, folhas adultas (fotossinteticamente ativas, brotações laterais, frutos e ramo. Os resultados obtidos permitiram o estabelecimento da sequência de metabolização do carbono-13 nas partições estudadas: Folhas novas > Frutos > Brotações > Folhas Adultas > Gema Apical > Ramo > Folha marcada. Plantas de figueira 'Roxo de Valinhos' apresentam reciclagem do 13C de 24 horas e um tempo de meia-vida de duração do carbono-13 inferior a 11 horas.

  7. XEROGELES DE CARBONO COMPETITIVOS DISEÑADOS PARA APLICACIONES ESPECÍFICAS

    Directory of Open Access Journals (Sweden)

    Ángel H. Moreno

    2013-01-01

    Full Text Available A pesar de su gran potencial, los xerogeles de carbono no se producen a gran escala debido a los largos y tediosos procesos tradicionales de obtención. El objetivo ha sido desarrollar un nuevo método de síntesis que permita su producción a gran escala de forma competitiva, sin perder el control de las propiedades y la posibilidad de producirlos a medida de cada aplicación. En este trabajo se presenta un nuevo proceso de obtención que permite reducir notablemente el tiempo del proceso de síntesis (>75% y utilizando un único dispositivo, constituyendo un paso muy importante para la implementación a escala industrial de la producción de xerogeles de carbono. En este trabajo se presentan resultados notables de dichos xerogeles de carbono en aplicaciones tan diversas como el almacenamiento de hidrógeno, como material activo en supercondensadores o como material de relleno en columnas de separación de gases, mostrando la gran versatilidad de estos materiales.

  8. grlc Makes GitHub Taste Like Linked Data APIs

    NARCIS (Netherlands)

    Meroño-Peñuela, A.; Hoekstra, Rinke; Sack, H; Rizzo, G; Steinmetz, N; Mladenić, D; Auer, S; Lange, C

    2016-01-01

    Building Web APIs on top of SPARQL endpoints is becoming a common practice to enable universal access to the integration favorable dataspace of Linked Data. However, the Linked Data community cannot expect users to learn SPARQL to query this dataspace, and Web APIs are the most extended way of enabl

  9. API and CPTDC Jointly Promote Chinese Enterprises to Go Abroad

    Institute of Scientific and Technical Information of China (English)

    Li Chunhui

    2005-01-01

    @@ In order to push the certification forward and help more Chinese enterprises to go abroad, API (American Petroleum Institute) and CPTDC (China Petroleum Technology & Development Corporation) jointly held a meeting between March 4 and 8, 2004, to promote API certification of Chinese enterprises.

  10. Interfacing RASCAL with Java APIs. Automated mapping with Apache POI

    NARCIS (Netherlands)

    Marmanidis, G.

    2013-01-01

    Interfacing RASCAL with Java APIs and reusing existing implementations is a required functionality in order to reduce effort and time in contrast with implementing a new one from scratch. In this study we are trying to interface RASCAL with Apache POI, a Java implemented API in order to import and a

  11. Experience API: Flexible, Decentralized and Activity-Centric Data Collection

    Science.gov (United States)

    Kevan, Jonathan M.; Ryan, Paul R.

    2016-01-01

    This emerging technology report describes the Experience API (xAPI), a new e-learning specification designed to support the learning community in standardizing and collecting both formal and informal distributed learning activities. Informed by Activity Theory, a framework aligned with constructivism, data is collected in the form of activity…

  12. Investigating an API for resilient exascale computing.

    Energy Technology Data Exchange (ETDEWEB)

    Stearley, Jon R.; Tomkins, James; VanDyke, John P.; Ferreira, Kurt Brian; Laros, James H.,; Bridges, Patrick

    2013-05-01

    Increased HPC capability comes with increased complexity, part counts, and fault occurrences. In- creasing the resilience of systems and applications to faults is a critical requirement facing the viability of exascale systems, as the overhead of traditional checkpoint/restart is projected to outweigh its bene ts due to fault rates outpacing I/O bandwidths. As faults occur and propagate throughout hardware and software layers, pervasive noti cation and handling mechanisms are necessary. This report describes an initial investigation of fault types and programming interfaces to mitigate them. Proof-of-concept APIs are presented for the frequent and important cases of memory errors and node failures, and a strategy proposed for lesystem failures. These involve changes to the operating system, runtime, I/O library, and application layers. While a single API for fault handling among hardware and OS and application system-wide remains elusive, the e ort increased our understanding of both the mountainous challenges and the promising trailheads. 3

  13. API E MIELE NEL MEDITERRANEO ANTICO

    Directory of Open Access Journals (Sweden)

    Matteo Bormetti

    2014-09-01

    Full Text Available L’importanza del miele come sostanza culturalmente ed economicamente rilevante nel mondo antico non è stata ancora del tutto indagata. Il miele e le api sono nondimeno presenze assidue e trasversali ai generi e alle tipologie di fonti antiche greche e romane, ed è pertanto da esse che una ricerca sull’argomento deve partire. I manufatti, le tecniche e i concetti descritti dagli antichi devono però essere relazionati con cautela al materiale archeologico rinvenuto, per fare ciò pare indispensabile un approccio che tenga conto delle nozioni biologiche, etologiche e zootecniche di base. Attraverso quest’ottica sono state ricapitolate le evidenze materiali provenienti dal bacino del Mediterraneo e concernenti gli strumenti e le strutture relative all’apicoltura, dalle arnie agli apiari, peril lungo arco cronologico che va dall’età del bronzo alla tarda antichità. Ciò è possibile per la tematica apicola grazie alla conservatività delle tecniche, strettamente legate ai severi dettami della natura fino alla rivoluzione ottocentesca delle arnie razionali a telai mobili del reverendo Langstroth. Sono inoltre analizzati gli utilizzi più frequenti del miele per come descritti dalle fonti letterarie nonché le implicazioni di api e miele nella ritualità e nel simbolismo della morte, del genere e della regalità, sebbene i risultati siano scarsi data la povertà dei riscontri archeologici e la limitata attenzione di cui questo argomento ha fin ora goduto.

  14. Almacenamiento de carbono en especies predominantes de flora en el lago Chinchaycocha

    Directory of Open Access Journals (Sweden)

    Ronald Medrano Yanqui

    2012-12-01

    Full Text Available Objetivos: Evaluar la cantidad de carbono que almacenan las especies predominantes de flora del lago Chinchaycocha. Métodos: La investigación fue de tipo básica, de corte transversal y con un nivel exploratorio-comparativo. El estudio se hizo en tres ecosistemas dentro del humedal: bofedal, pajonal y totoral, las áreas fueron identificadas con ayuda de imágenes satelitales Landsat. El procedimiento estuvo basado en la recolección de muestras divididas en: biomasa aérea, biomasa radicular y muestras de suelo, hallándose el contenido de carbono de cada una. Resultados: En el totoral se obtuvo que Schoenoplectus californicus Var. Tatora almacena 30,65 tC/ha y Juncos arcticus Var. Andicola 8,70 tC/ha. En el pajonal Deyeuxia recta Kunth almacena 7,02 tC/ha en su biomasa aérea y 8,41 tC/ha en su biomasa radicular. En el bofedal: Plantago tubulosa almacena 0,81 t C/ha en su biomasa aérea y 1,88 t C/ha en su biomasa radicular, Eleocharis albibracteata almacena 0,22 t C/ha en su biomasa aérea y 2,95 tC/ha en su biomasa radicular, y Limosella australis almacena 0,22 tC/ha en su biomasa aérea y 0,38 tC/ha en su biomasa radicular. En el almacenamiento de carbono en suelos se determinó 774,76 tC/ ha en pajonales y 684,58 tC/ha en bofedales. Conclusiones: Se concluye que en el lago Chinchaycocha el ecosistema que brinda mayor almacenamiento de carbono es el totoral, seguido por el pajonal y en menor proporción el bofedal. Asimismo los suelos son considerados los mayores sumideros de carbono.

  15. CARBONO LÁBIL COMO UN INDICADOR DE CAMBIOS EN DOS SUELOS BAJO DIFERENTES USOS

    Directory of Open Access Journals (Sweden)

    Milagros Ginebra Aguilar

    2015-01-01

    Full Text Available La materia orgánica en el suelo es un componente clave en la reserva y ciclo del carbono. En condiciones naturales el carbono se incorpora al suelo a través del aporte continuo de material orgánico; sin embargo, existen prácticas de uso de la tierra que generan una disminución del carbono orgánico en el tiempo, a la vez hay prácticas de uso sostenible que favorecen su captura y acumulación. La determinación de fracciones lábiles de carbono orgánico del suelo, constituye una práctica frecuente para evaluar cambios en la calidad de la materia orgánica bajo distintos manejos. Se comparó el contenido de carbono lábil (COS L en la capa 0-20 cm de un suelo Ferralítico Rojo Típico con el de un Ferrítico Rojo Oscuro Típico, sometidos a tres usos del suelo (sin explotación, cultivo diversificado y cultivo intensivo. La extracción del COS L se realizó por oxidación con permanganato de potasio a 0,02 mg L -1 y las determinaciones se hicieron colorimétricamente. Se encontró que independientemente del uso, el contenido de COS L fue superior en el suelo Ferralítico que en el Ferrítico y que para ambos suelos los contenidos disminuyeron en las áreas bajo cultivo intensivo con relación a las áreas sin explotación; además, en el sistema diversificado, donde se aplican principios de Manejo Sostenible de Tierras, este indicador tiende a recuperarse. Estos resultados sugieren la inclusión de la determinación del COS L , como indicador de alerta del efecto de los usos del suelo sobre su calidad

  16. Coming 5th Edition of the API Standard 618: major changes compared to the API 618, 4th edition

    NARCIS (Netherlands)

    Pyle, A.; Eijk, A.; Elferink, H.

    2003-01-01

    This paper will present the highlights of changes that will be found in the 5th Edition of API 618, which is expected to be published in late 2003 or early 2004. Approximately every 5 years the API Standards are revised in such a way that the latest field experiences and proven designs are included

  17. Comparison of learning and memory of Apis cerana and Apis mellifera.

    Science.gov (United States)

    Qin, Qiu-Hong; He, Xu-Jiang; Tian, Liu-Qing; Zhang, Shao-Wu; Zeng, Zhi-Jiang

    2012-10-01

    The honeybee is an excellent model organism for research on learning and memory among invertebrates. Learning and memory in honeybees has intrigued neuroscientists and entomologists in the last few decades, but attention has focused almost solely on the Western honeybee, Apis mellifera. In contrast, there have been few studies on learning and memory in the Eastern honeybee, Apis cerana. Here we report comparative behavioral data of color and grating learning and memory for A. cerana and A. mellifera in China, gathered using a Y-maze apparatus. We show for the first time that the learning and memory performance of A. cerana is significantly better on both color and grating patterns than that of A. mellifera. This study provides the first evidence of a learning and memory difference between A. cerana and A. mellifera under controlled conditions, and it is an important basis for the further study of the mechanism of learning and memory in honeybees.

  18. Compositional mining of multiple object API protocols through state abstraction.

    Science.gov (United States)

    Dai, Ziying; Mao, Xiaoguang; Lei, Yan; Qi, Yuhua; Wang, Rui; Gu, Bin

    2013-01-01

    API protocols specify correct sequences of method invocations. Despite their usefulness, API protocols are often unavailable in practice because writing them is cumbersome and error prone. Multiple object API protocols are more expressive than single object API protocols. However, the huge number of objects of typical object-oriented programs poses a major challenge to the automatic mining of multiple object API protocols: besides maintaining scalability, it is important to capture various object interactions. Current approaches utilize various heuristics to focus on small sets of methods. In this paper, we present a general, scalable, multiple object API protocols mining approach that can capture all object interactions. Our approach uses abstract field values to label object states during the mining process. We first mine single object typestates as finite state automata whose transitions are annotated with states of interacting objects before and after the execution of the corresponding method and then construct multiple object API protocols by composing these annotated single object typestates. We implement our approach for Java and evaluate it through a series of experiments.

  19. The pheromones of laying workers in two honeybee sister species: Apis cerana and Apis mellifera.

    Science.gov (United States)

    Tan, Ken; Yang, Mingxian; Wang, Zhengwei; Radloff, Sarah E; Pirk, Christian W W

    2012-04-01

    When a honeybee colony loses its queen, workers activate their ovaries and begin to lay eggs. This is accompanied by a shift in their pheromonal bouquet, which becomes more queen like. Workers of the Asian hive bee Apis cerana show unusually high levels of ovary activation and this can be interpreted as evidence for a recent evolutionary arms race between queens and workers over worker reproduction in this species. To further explore this, we compared the rate of pheromonal bouquet change between two honeybee sister species of Apis cerana and Apis mellifera under queenright and queenless conditions. We show that in both species, the pheromonal components HOB, 9-ODA, HVA, 9-HDA, 10-HDAA and 10-HDA have significantly higher amounts in laying workers than in non-laying workers. In the queenright colonies of A. mellifera and A. cerana, the ratios (9-ODA)/(9-ODA + 9-HDA + 10-HDAA + 10-HDA) are not significantly different between the two species, but in queenless A. cerana colonies the ratio is significant higher than in A. mellifera, suggesting that in A. cerana, the workers' pheromonal bouquet is dominated by the queen compound, 9-ODA. The amount of 9-ODA in laying A. cerana workers increased by over 585% compared with the non-laying workers, that is 6.75 times higher than in A. mellifera where laying workers only had 86% more 9-ODA compared with non-laying workers.

  20. A framework for API solubility modelling

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul; Crafts, Peter

    The solubility of solid organic compounds in water and organic solvents is a fundamental thermodynamic property for many purposes such as product-process design and optimization, for the chemical and pharmaceutical industry. Experimental literature solubility data are usually scarce and temperature......-dependent measurements are expensive in terms of time and resources. The few available data are badly organized and difficult to use for fast solubility calculations and solvent screening. Available models often require time consuming and complex implementation together with a good user expertise for their efficient use....... In addition, most of the models are not predictive and requires experimental data for the calculation of the needed parameters. This work aims at developing an efficient framework for the solubility modelling of Active Pharmaceutical Ingredients (API) in water and organic solvents. With this framework...

  1. Building Hypermedia APIs with HTML5 and Node

    CERN Document Server

    Amundsen, Mike

    2011-01-01

    With this concise book, you'll learn the art of building hypermedia APIs that don't simply run on the Web, but that actually exist in the Web. You'll start with the general principles and technologies behind this architectural approach, and then dive hands-on into three fully-functional API examples. Too many APIs rely on concepts rooted in desktop and local area network patterns that don't scale well-costly solutions that are difficult to maintain over time. This book shows system architects and web developers how to design and implement human- and machine-readable web services that remain

  2. Incentivos econômicos e projeto de supply chain para captura e sequestro de carbono: caso Brasil

    Directory of Open Access Journals (Sweden)

    Ernesto del Rosario Santibañez Gonzalez

    2014-12-01

    Full Text Available Neste artigo, analisamos uma estratégia para reduzir as emissões de carbono que combina simultaneamente a criação de políticas de incentivo econômico e o desenvolvimento de uma infraestrutura de rede para captura e sequestro de carbono (CCS. Propomos um modelo de otimização linear inteira mista que considera aspectos técnicos e teóricos e permite analisar simultaneamente os efeitos de estabelecer preços para as emissões de carbono (carbon tax em conjunto com uma estratégia de implementação de uma rede de supply chain para capturar, transportar e sequestrar CO2 em reservatórios geológicos. Apresentamos resultados para o caso da indústria de cimento do Brasil usando CO2 tax estabelecidas atualmente em outros países.

  3. A PEGADA DE CARBONO DA UNIDADE SEDE DA PETROBRAS EM NATAL-RN

    Directory of Open Access Journals (Sweden)

    Ricardo Teixeira Gregório Andrade

    2011-03-01

    Full Text Available Face ao contexto contemporâneo das alterações climáticas, os setores industriais e empresariais têm buscado medidas para minimizar os impactos das suas emissões de Gases Efeito Estufa. Contudo, a maioria das ações de Responsabilidade SocioAmbiental Empresarial quanto à temática referem-se apenas às emissões diretas dos principais processos produtivos empresariais, sem considerar as emissões upstream e downstream, que originam a maior parte das emissões derivadas da existência de uma empresa. A consideração das emissões de todo o ciclo de vida produtivo de produtos e processos, desde a extração da matéria-prima até a distribuição do produto final e descarte, constitui a Pegada de Carbono. O objetivo desse estudo foi a mensuração, e estudo de formas de minoração, de parte da Pegada de Carbono da Unidade Sede da Petrobras em Natal-RN. Trata-se de um levantamento, em que os dados foram submetidos à metodologia apropriada e laborados com uso do software GEMIS 4.6. Os itens avaliados foram os veículos automotivos (emissões diretas, energia elétrica, papel e copos plásticos descartáveis (emissões indiretas, totalizando emissões de 3.811,94 tCO2eq em 2009. Dado o porte da Petrobras, sua atenção quanto à redução de sua Pegada de Carbono serve de exemplo a outras empresas, instruindo lições de gestão e melhores práticas ambientais.

  4. Estudio reológico de dispersiones de líquido iónico con nanotubos de carbono

    OpenAIRE

    García Sánchez, Juan

    2012-01-01

    Los objetivos principales de este proyecto son:1. Caracterización reológica de líquido iónico y dispersiones con nanotubos de carbono. 2. Estudio comparativo del comportamiento reológico de líquido iónico y dispersiones con nanotubos de carbono. 3. Influencia de la temperatura. 4. Influencia de la velocidad de cizalla. 5. Determinación de las curvas de viscosidad Escuela Técnica Superior de Ingeniería Industrial Universidad Politécnica de Cartagena

  5. Balanço de carbono em fotobiorreato com cultivo de Chlorella bulgaris em excesso de 'C 'O IND.2'

    OpenAIRE

    Mônica Regina Piovani

    2012-01-01

    Resumo: As microalgas são microrganismos que vem sendo utilizados na bioconversão de carbono em produtos com interesse comercial como, por exemplo, biocombustíveis, corantes, suplementos alimentares e cosméticos. Elas podem ser cultivadas em sistemas autotróficos e heterotróficas sendo que as fontes de carbono, gasosas ou líquidas, podem ser provenientes de resíduos industriais reduzindo os custos de sua produção. Para identificar quais os possíveis produtos gerados durante o cultivo o objeti...

  6. Reserva de carbono en biomasa forestal y suelos minerales en el Parque Nacional Malinche (México)

    OpenAIRE

    María Eugenia Valdez Pérez; Gandhi González Guerrero; Rafael Morales Ibarra; Rut Yadira Bolaños Suárez

    2016-01-01

    Las áreas naturales protegidas representan una de las estrategias para la mitigación del cambio climático. El objetivo de esta investigación consistió en estimar el contenido de carbono en biomasa forestal en suelos minerales y calcular las pérdidas de carbono por cambios de uso del suelo en el Parque Nacional Malinche (PNM). La superficie de bosque del PNM es de 17.496,34 ha y almacena 1.544.377,66 mg en bosque y 4.148.985,97 mg en suelos. Para estimar el contenido de biomasa forestal se apl...

  7. Tóxicos detectados en muertes relacionadas con fuegos e intoxicaciones por monóxido de carbono

    OpenAIRE

    2003-01-01

    Se presentan en este trabajo las conclusiones del estudio realizado sobre los resultados de los análisis efectuados en muestras de sangre de 882 personas que resultaron fallecidas o intoxicadas en fuegos o a consecuencia de la inhalación de monóxido de carbono y/o de otros gases de combustión. En ellas se investigó la presencia de monóxido de carbono, cianuro y otros tóxicos tales como el alcohol etílico y los psicofármacos. Se realizan dos subgrupos, el de muertes produc...

  8. Uma modelagem de sequestro e armazenamento de dióxido de carbono atmosférico

    OpenAIRE

    Ferrufino, Gretta Larisa Aurora Arce [UNESP

    2008-01-01

    O dióxido de carbono (CO2) é um importante gás de efeito estufa. No entanto, um aumento gradual ameaça substancialmente o clima. Um dos principais desafios do planejamento ambiental é identificar um modelo que vincule todos os fatores do ciclo de carbono, ou seja, oceano – ecossistema terrestre – emissão antropogênica – atmosfera. Princípios básicos de Termodinâmica podem ser aplicados em uma modelagem estatística com bases em séries históricas para obter concentrações de CO2 na atmosfera, po...

  9. Materiales de carbono para desalinización de aguas mediante desionización capacitiva

    OpenAIRE

    Díaz Baizán, Patricia

    2012-01-01

    El presente trabajo muestra los resultados obtenidos al emplear materiales de carbono de elevada área superficial en el proceso de desalinización de aguas mediante desionización capacitiva (CDI). Esta técnica electroquímica, basada en la formación de la doble capa eléctrica en la interfase electrodo/electrolito para retener las sales presentes en el agua tratada, es una alternativa energéticamente menos costosa a las tecnologías comúnmente empleadas como son la ósmosis inversa y la destilació...

  10. Financiamiento de proyectos urbano-ecológicos mediante intercambio de bonos de carbono

    OpenAIRE

    Gino Pérez Lancellotti

    2015-01-01

    Esta publicación, presenta una de las posibilidades que existen hoy en el mundo de poder fi nanciar en parte ya sea la construcción, la operación o el mantenimiento de proyectos urbanos y territoriales, diseñados o ejecutados dentro de un esquema de sustentabilidad y amabilidad con el Medio Ambiente. Se trata de la generación por parte de estos proyectos de los llamados Bonos Verdes o bonos de carbono los cuales pueden ser transados en el mercado internacional. Los proyectos que pueden gen...

  11. FINANCIAMIENTO DE PROYECTOS URBANO-ECOLÓGICOS MEDIANTE INTERCAMBIO DE BONOS DE CARBONO

    Directory of Open Access Journals (Sweden)

    Gino Pérez Lancellotti

    2010-01-01

    a diversas escalas, nos concentraremos específi camente en proyectos a escala urbana, los llamados proyectos "Ecociudad". Los bonos verdes o bonos de carbono, son instrumentos fi nancieros hasta hoy muy utilizados en proyectos más bien ligados a la generación de energías renovables. Este trabajo, revisará principalmente algunos proyectos de Ecociudad que se están llevando, a cabo y específi camente el caso de Dongtan en China.

  12. CAMBIOS EN LAS RESERVAS DE CARBONO ORGÁNICO DEL SUELO BAJO DIFERENTES COBERTURAS

    OpenAIRE

    José I. Bojórquez Serrano; Lucía A. Castillo Pacheco; Alberto Hernández Jiménez; Juan D. García Paredes; Alberto Madueño Molina

    2015-01-01

    Las reservas de carbono orgánico en los suelos (COS) y sus cambios en el tiempo son un tema ambiental de actualidad, asimismo las pérdidas de COS que ocurren con la conversión de ecosistemas naturales a agrosistemas, contribuyen con emisiones a la atmósfera, al calentamiento global y el cambio climático. El objetivo de este trabajo fue estudiar los cambios en las reservas de COS bajo diferentes coberturas de la cuenca del río Mololoa, Nayarit, México. El análisis de los cambios se rea...

  13. Efecto del boro en la deformación en caliente de un acero al carbono

    OpenAIRE

    2005-01-01

    En el presente estudio se evalúa el comportamiento a fluencia de tres aceros al carbono con distinto contenido en boro. Las curvas de fluencia se han obtenido a partir de ensayos de compresión uniaxial en caliente, realizada sobre probetas cilíndricas en una máquina de ensayos INSTRON que disponía de un horno de calentamiento por radiación adaptado al sistema. Los ensayos se realizaron a velocidad de deformación constante de 0,1s-1, 0,01s-1 y 0,001s-1, y las temperaturas de ens...

  14. Efecto del contenido de silicio en el comportamiento a fluencia de un acero al carbono

    OpenAIRE

    2004-01-01

    En el presente estudio se evalúa el comportamiento a fluencia de tres aceros al carbono con distinto contenido en silicio. Las curvas experimentales de fluencia se han obtenido a partir de ensayos de compresión en caliente, realizados sobre probetas cilíndricas en una máquina universal de ensayos, que disponía de un horno de calentamiento por radiación adaptado al sistema. Los ensayos se realizaron a velocidades de deformación constante sobre un intervalo de 3·10-4 s-1 a 0,1 s-1, y a las temp...

  15. Variacion del modulo de 'Young' con el tratamiento termico en aceros al carbono hipoeutectoides

    OpenAIRE

    Villuendas Latorre, Aránzazu; Jorba, Jordi; Roca, Antoni

    2005-01-01

    En trabajos anteriores se ha constatado que varios aceros al carbono hipoeutectoides, en estado de temple, presentan valores del módulo de Young inferiores a los correspondientes en estado de revenido. En todos los casos la determinación se ha realizado mediante ultrasonidos. En concreto, para el acero C22E (EN 10083), el módulo se incrementa ligeramente desde 209 GPa (material templado) hasta 211 GPa (revenido a 650 °C), para el acero C45E el módulo aumenta desde 199 GPa hasta 211 GPa (reven...

  16. Anclaje químico para barras de fibra de carbono. Aproximación experimental

    OpenAIRE

    2010-01-01

    Se han llevado a cabo diferentes ensayos experimentales casi – estáticos en un entorno de laboratorio para poder determinar el diagrama de tensión tangencial en las uniones adhesivas entre resina estructural y laminado fibra de carbono. Por otra parte, se ha determinado la tensión tangencial media en el momento de rotura de dicha unión. Toda esta información experimental se ha contrastado con el método analítico de Volkersen de uniones adhesivas de doble solape. Puesto que los valores e...

  17. Videografia digital na estimativa de carbono em florestas implantadas com espécies nativas

    OpenAIRE

    Couto, Hilton Thadeu Zarate do; Universidade de São Paulo - USP - Escola Superior de Agricultura Queiroz Filho; Justo, Guilherme do Couto; Universidade de São Paulo - USP - Escola Superior de Agricultura Queiroz Filho; Polizel, Jefferson Lordelo; Universidade de São Paulo - USP; Silva Filho, Demóstenes Ferreira da; Universidade de São Paulo - USP

    2009-01-01

    O objetivo do presente trabalho e utilizar a videografia digital como ferramenta para a estimativa do carbono em florestas implantadas com essências nativas, utilizando para isso o índice de vegetação NDVI. As imagens aéreas foram obtidas com o auxilio de uma aeronave modelo Cessna 180, equipada com o sistema de rastreamento e armazenamento de dados, que inclui uma câmera digital multiespectral de alta resolução. A partir das imagens geradas pelo sistema foi analisado o índice de vegetação ou...

  18. Practical Implementation of 10 Rules for Writing REST APIs

    Directory of Open Access Journals (Sweden)

    Jiri Hradil

    2017-01-01

    Full Text Available This paper shows a practical implementation of “10 Rules for Writing REST APIs introduced in the article” (Hradil, 2016. The application is done in Invoice Home (Wikilane, 2016, an invoicing web application for small business and entrepreneurs available world-wide. The API is implemented in JSON hypermedia format (ECMA International, 2016 and with Ruby on Rails framework (Hansson, 2016. The main purpose of the API is to allow connection of Invoice Home with external systems and offer Invoice Home data in simpler format compared to the current HTML format of the full-stack web application. The paper could be also used as a basic template or pattern for any other implementation of the JSON API in any web-based application.

  19. Drone competition at drone congregation areas in four Apis species

    OpenAIRE

    2005-01-01

    International audience; In Apis mellifera the estimated average number of drones visiting a drone congregation area (DCA) was 11 750 + 2 145. Drones of the species Apis cerana, A. koschevnikovi, A. dorsata and A. mellifera, which pursued a queen dummy moving in circular course, flew in a comet shaped formation. Median numbers of drones in a comet ranged from 9 drones (A. koschevnikovi) to 31 drones (A. mellifera). In none of the species we observed aggression between drones. Drone density beh...

  20. Pengaruh Busur Api Terhadap Kekuatan Dielektrik Gas SF6

    OpenAIRE

    Jhony

    2011-01-01

    Bahan isolasi gas yang sering digunakan adalah gas SF6. Sifat –sifat dari gas SF6 ini tidak berwarna, tidak beracun, tidak berbau. Salah satu pemanfaatan dari gas SF6 ini sebagai bahan isolasi adalah pada pemutus tenaga (circuit breaker). Jika pemutus tenaga SF6 membuka, maka pada sela kontaknya akan terjadi busur api. Busur api akan menaikkan temperatur gas SF6 sehingga ada dugaan gas SF6 mengalami perubahan struktur kimia, sehingga sifat listriknya berubah. Tugas akhir ini ak...

  1. GIANT API: an application programming interface for functional genomics

    Science.gov (United States)

    Roberts, Andrew M.; Wong, Aaron K.; Fisk, Ian; Troyanskaya, Olga G.

    2016-01-01

    GIANT API provides biomedical researchers programmatic access to tissue-specific and global networks in humans and model organisms, and associated tools, which includes functional re-prioritization of existing genome-wide association study (GWAS) data. Using tissue-specific interaction networks, researchers are able to predict relationships between genes specific to a tissue or cell lineage, identify the changing roles of genes across tissues and uncover disease-gene associations. Additionally, GIANT API enables computational tools like NetWAS, which leverages tissue-specific networks for re-prioritization of GWAS results. The web services covered by the API include 144 tissue-specific functional gene networks in human, global functional networks for human and six common model organisms and the NetWAS method. GIANT API conforms to the REST architecture, which makes it stateless, cacheable and highly scalable. It can be used by a diverse range of clients including web browsers, command terminals, programming languages and standalone apps for data analysis and visualization. The API is freely available for use at http://giant-api.princeton.edu. PMID:27098035

  2. Mining Effective Temporal Specifications from Heterogeneous API Data

    Institute of Scientific and Technical Information of China (English)

    Qian Wu; Guang-Tai Liang; Qian-Xiang Wang; Hong Mei

    2011-01-01

    Temporal specifications for Application Programming Interfaces (APIs) serve as an important basis for many defect detection tools.As these specifications are often not well documented,various approaches have been proposed to automatically mine specifications typically from API library source code or from API client programs.However,the library-based approaches take substantial computational resources and produce rather limited useful specifications,while the client-based approaches suffer from high false positive rates.To address the issues of existing approaches,we propose a novel specification miniug approach,called MineHEAD,which exploits heterogeneous API data,including information from API client programs as well as API library source code and comments,to produce effective specifications for defect detection with low cost.In particular,MineHEAD first applies client-based specification mining to produce a collection of candidate specifications,and then exploits the related library source code and comments to identify and refine the real specifications from the candidates.Our evaluation results on nine open source projects show that MineHEAD produces effective specifications with average precision of 97.2%.

  3. GIANT API: an application programming interface for functional genomics.

    Science.gov (United States)

    Roberts, Andrew M; Wong, Aaron K; Fisk, Ian; Troyanskaya, Olga G

    2016-07-08

    GIANT API provides biomedical researchers programmatic access to tissue-specific and global networks in humans and model organisms, and associated tools, which includes functional re-prioritization of existing genome-wide association study (GWAS) data. Using tissue-specific interaction networks, researchers are able to predict relationships between genes specific to a tissue or cell lineage, identify the changing roles of genes across tissues and uncover disease-gene associations. Additionally, GIANT API enables computational tools like NetWAS, which leverages tissue-specific networks for re-prioritization of GWAS results. The web services covered by the API include 144 tissue-specific functional gene networks in human, global functional networks for human and six common model organisms and the NetWAS method. GIANT API conforms to the REST architecture, which makes it stateless, cacheable and highly scalable. It can be used by a diverse range of clients including web browsers, command terminals, programming languages and standalone apps for data analysis and visualization. The API is freely available for use at http://giant-api.princeton.edu.

  4. Identification of Complete Repertoire of Apis florea Odorant Receptors Reveals Complex Orthologous Relationships with Apis mellifera.

    Science.gov (United States)

    Karpe, Snehal D; Jain, Rikesh; Brockmann, Axel; Sowdhamini, Ramanathan

    2016-09-26

    We developed a computational pipeline for homology based identification of the complete repertoire of olfactory receptor (OR) genes in the Asian honey bee species, Apis florea Apis florea is phylogenetically the most basal honey bee species and also the most distant sister species to the Western honey bee Apis mellifera, for which all OR genes had been identified before. Using our pipeline, we identified 180 OR genes in A. florea, which is very similar to the number of ORs identified in A. mellifera (177 ORs). Many characteristics of the ORs including gene structure, synteny of tandemly repeated ORs and basic phylogenetic clustering are highly conserved. The composite phylogenetic tree of A. florea and A. mellifera ORs could be divided into 21 clades which are in harmony with the existing Hymenopteran tree. However, we found a few nonorthologous OR relationships between both species as well as independent pseudogenization of ORs suggesting separate evolutionary changes. Particularly, a subgroup of the OR gene clade XI, which had been hypothesized to code cuticular hydrocarbon receptors showed a high number of species-specific ORs RNAseq analysis detected a total number of 145 OR transcripts in male and 162 in female antennae. Most of the OR genes were highly expressed on the female antennae. However, we detected five distinct male-biased OR genes, out of which three genes (AfOr11, AfOr18, AfOr170P) were shown to be male-biased in A. mellifera, too, thus corroborating a behavioral function in sex-pheromone communication.

  5. Variance in spermatozoa number among Apis dorsata drones and among Apis mellifera drones

    OpenAIRE

    Koeniger, Gudrun; KOENIGER, Nikolaus; Tingek, Salim; Phiancharoen, Mananya

    2005-01-01

    International audience; Published estimates of the mean spermatozoa numbers for Apis dorsata drones vary from 1.2 × 106 and 2.4 × 106; the number of spermatozoa per individual drone vary from 0.22 × 106 to 2.65 × 106. Counts presented here revealed 1.19 × 106 + 0.25 × 106 spermatozoa in drones sampled near a colony and 1.59 × 106 + 0.18 × 106 in drones sampled at a drone congregation area (DCA) in Sabah, Borneo. The difference between the two sites is significant. Further, the degree of varia...

  6. Honeybee (Apis mellifera ligustica) drone embryo proteomes.

    Science.gov (United States)

    Li, Jianke; Fang, Yu; Zhang, Lan; Begna, Desalegn

    2011-03-01

    Little attention has been paid to the drone honeybee (Apis mellifera ligustica) which is a haploid individual carrying only the set of alleles that it inherits from its mother. Molecular mechanisms underlying drone embryogenesis are poorly understood. This study evaluated protein expression profiles of drone embryogenesis at embryonic ages of 24, 48 and 72h. More than 100 reproducible proteins were analyzed by mass spectrometry on 2D electrophoresis gels. Sixty-two proteins were significantly changed at the selected three experimental age points. Expression of the metabolic energy requirement-related protein peaked at the embryonic age of 48h, whereas development and metabolizing amino acid-related proteins expressed optimally at 72h. Cytoskeleton, protein folding and antioxidant-related proteins were highly expressed at 48 and 72h. Protein networks of the identified proteins were constructed and protein expressions were validated at the transcription level. This first proteomic study of drone embryogenesis in the honeybee may provide geneticists an exact timetable and candidate protein outline for further manipulations of drone stem cells.

  7. The Apis mellifera Filamentous Virus Genome

    Directory of Open Access Journals (Sweden)

    Laurent Gauthier

    2015-07-01

    Full Text Available A complete reference genome of the Apis mellifera Filamentous virus (AmFV was determined using Illumina Hiseq sequencing. The AmFV genome is a double stranded DNA molecule of approximately 498,500 nucleotides with a GC content of 50.8%. It encompasses 247 non-overlapping open reading frames (ORFs, equally distributed on both strands, which cover 65% of the genome. While most of the ORFs lacked threshold sequence alignments to reference protein databases, twenty-eight were found to display significant homologies with proteins present in other large double stranded DNA viruses. Remarkably, 13 ORFs had strong similarity with typical baculovirus domains such as PIFs (per os infectivity factor genes: pif-1, pif-2, pif-3 and p74 and BRO (Baculovirus Repeated Open Reading Frame. The putative AmFV DNA polymerase is of type B, but is only distantly related to those of the baculoviruses. The ORFs encoding proteins involved in nucleotide metabolism had the highest percent identity to viral proteins in GenBank. Other notable features include the presence of several collagen-like, chitin-binding, kinesin and pacifastin domains. Due to the large size of the AmFV genome and the inconsistent affiliation with other large double stranded DNA virus families infecting invertebrates, AmFV may belong to a new virus family.

  8. The Apis mellifera Filamentous Virus Genome.

    Science.gov (United States)

    Gauthier, Laurent; Cornman, Scott; Hartmann, Ulrike; Cousserans, François; Evans, Jay D; de Miranda, Joachim R; Neumann, Peter

    2015-07-09

    A complete reference genome of the Apis mellifera Filamentous virus (AmFV) was determined using Illumina Hiseq sequencing. The AmFV genome is a double stranded DNA molecule of approximately 498,500 nucleotides with a GC content of 50.8%. It encompasses 247 non-overlapping open reading frames (ORFs), equally distributed on both strands, which cover 65% of the genome. While most of the ORFs lacked threshold sequence alignments to reference protein databases, twenty-eight were found to display significant homologies with proteins present in other large double stranded DNA viruses. Remarkably, 13 ORFs had strong similarity with typical baculovirus domains such as PIFs (per os infectivity factor genes: pif-1, pif-2, pif-3 and p74) and BRO (Baculovirus Repeated Open Reading Frame). The putative AmFV DNA polymerase is of type B, but is only distantly related to those of the baculoviruses. The ORFs encoding proteins involved in nucleotide metabolism had the highest percent identity to viral proteins in GenBank. Other notable features include the presence of several collagen-like, chitin-binding, kinesin and pacifastin domains. Due to the large size of the AmFV genome and the inconsistent affiliation with other large double stranded DNA virus families infecting invertebrates, AmFV may belong to a new virus family.

  9. Uso de dióxido de carbono na agricultura Use of carbon dioxide in agriculture

    Directory of Open Access Journals (Sweden)

    José Maria Pinto

    2000-10-01

    Full Text Available O ciclo do carbono na biosfera tem sido significativamente alterado pela atividade do homem nos últimos 150 anos. O CO2 emitido pela atividade humana é da ordem de 8,5 bilhões de toneladas anuais, como conseqüência a concentração de CO2 atmosférico está aumentando. Estudos relacionando os efeitos do aumento artificial da concentração de CO2 nas plantas para obtenção de produtos em maior quantidade e melhor qualidade permitem conhecer a capacidade das plantas de adaptarem-se a esses ambientes. No entanto, fatores relacionados à aplicação de dióxido de carbono necessitam de estudos ecofisiológicos mais detalhados referentes às trocas de CO2.The carbon cycle in the biosphere has been significantly altered by man's activities in the last 150 years. The CO2 emitted by human activity is approximately 8.5 billion of tons yearly, as a consequence, the carbon dioxide concentration is increasing. Studies related to the artificial increase effects of CO2 concentration on plants used for obtaining products in greater quantity and with a better quality permit us to know the capacity of the plants to adapt in this environment. Therefore, factors related to the application of carbon dioxide need more accurate studies concerning to carbon dioxide changes.

  10. Nanotubos de carbono: Estructura porosa y sus implicaciones en el campo de la energía

    OpenAIRE

    Ansón Casaos, Alejandro

    2005-01-01

    Tesis doctoral Universidad de Zaragoza, Facultad de Ciencias, Departamento de Química Orgánica y Química Física e Instituto de Carboquímica (ICB-CSIC), Grupo de Nanoestructuras de Carbono y Nanotecnología.-- Fecha de lectura: 01/04/2005

  11. Inhibiting DNA methylation alters olfactory extinction but not acquisition learning in Apis cerana and Apis mellifera.

    Science.gov (United States)

    Gong, Zhiwen; Wang, Chao; Nieh, James C; Tan, Ken

    2016-07-01

    DNA methylation plays a key role in invertebrate acquisition and extinction memory. Honey bees have excellent olfactory learning, but the role of DNA methylation in memory formation has, to date, only been studied in Apis mellifera. We inhibited DNA methylation by inhibiting DNA methyltransferase (DNMT) with zebularine (zeb) and studied the resulting effects upon olfactory acquisition and extinction memory in two honey bee species, Apis cerana and A. mellifera. We used the proboscis extension reflex (PER) assay to measure memory. We provide the first demonstration that DNA methylation is also important in the olfactory extinction learning of A. cerana. DNMT did not reduce acquisition learning in either species. However, zeb bidirectionally and differentially altered extinction learning in both species. In particular, zeb provided 1h before acquisition learning improved extinction memory retention in A. mellifera, but reduced extinction memory retention in A. cerana. The reasons for these differences are unclear, but provide a basis for future studies to explore species-specific differences in the effects of methylation on memory formation.

  12. Tozaltı Ark Kaynak Yöntemi ile Birleştirilen X60, X65 ve X70 Çeliklerin Kaynak Bölgesinin Etüdü

    Directory of Open Access Journals (Sweden)

    Ali Akın Akay, ,

    2013-12-01

    Full Text Available Bu çalışmada, petrol ve doğal gaz hatlarında kullanılan, düşük alaşımlı, ince taneli ve yüksek mukavemetli X60, X65 ve X70 çelikleri, tozaltı ark kaynak yöntemi ile iki farklı tel (S1 ve S2Mo ve toz (LN761 ve P223 kullanılarak birleştirilmiştir. Kaynaklı birleştirmelere, öncelikle yüzey ve yüzey altı kusurların belirlenebilmesi için tahribatsız muayene yöntemlerinden gözle ve ultrasonik muayeneye teknikleri uygulanmış, sonrasında birleştirmelerin dayanımlarını belirlemek amacıyla, çekme ve eğme testi uygulanmıştır. Ayrıca numuneler üzerinde sertlik ve makroyapı çalışmaları gerçekleştirilmiştir. Kaynaklı numuneler üzerinde yapılan gözle ve ultrasonik muayene sonucunda, kaynak bölgesinde herhangi bir kaynak hatasına rastlanılmamıştır. Yapılan çekme testleri sonucunda, tüm numunelerde kopma, ana malzemeden gerçekleşmiş ve bütün bağlantı dayanımları, ana malzemelerden daha yüksek bulunmuştur. Eğme testleri sonucunda, kaynak bölgesinde herhangi bir çatlak, yırtık vb. hata görülmemiştir. Yapılan sertlik testleri sonucunda, en yüksek sertlik değerleri kaynak metalinden ölçülürken onu sırasıyla ITAB ve ana malzeme takip etmektedir. Makroyapı resimleri incelendiğinde kaynak bölgesinde çatlaklara, yırtılmalara, boşluklara, ergime/nüfuziyet azlığına, curuf kalıntılarına ve yanma oluklarına rastlanılmamıştır. Deney sonuçları genel olarak değerlendirildiğinde, X70 malzemede kullanılan, S2Mo teli ve P223 tozu en verimli mekanik test sonuçları vermiştir.

  13. Factores críticos para lograr la carbono neutralidad: Mejorando la vinculación del sector forestal costarricense con las empresas C-Neutral

    OpenAIRE

    Meza-Picado, Víctor; Chavarría-Vargas, Manuel; Barrantes-Rodríguez, Alfonso

    2016-01-01

    : Costa Rica se propuso alcanzar la "carbono neutralidad" para el año 2021. Para lograrlo, dos actores claves han sido identificados: por un lado se encuentran las organizaciones que contribuyen con la emisión de gases de efecto invernadero y; por otro, el componente forestal, el cual contribuye a la mitigación por medio de la remoción y almacenamiento del dióxido de carbono en sus componentes. Con la intención de alcanzar la Marca País C-Neutral (lograr la declaración de carbono neutralidad ...

  14. Estoques de carbono e agregados do solo cultivado com cana-de-açucar: efeito da palhada e do clima no centro-sul do Brasil

    OpenAIRE

    Gábor Gyula Julius Szakács

    2007-01-01

    O estudo foi dividido em quatro partes. Na primeira parte analisou-se o impacto do clima na estocagem de carbono em solos de canaviais sem a queima da palhada. Foram escolhidos três regimes climáticos contrastantes do centro-sul do Brasil. O potencial de seqüestro de carbono orgânica no solo (COS) foi determinado, em cada regime climático, de acordo com a taxa anual de carbono remanescente no solo proveniente da palhada depositada. Para obter esta taxa, compararam-se os estoques de COS em can...

  15. A quick guide to API 510 certified pressure vessel inspector syllabus example questions and worked answers

    CERN Document Server

    Matthews, Clifford

    2010-01-01

    The API Individual Certification Programs (ICPs) are well established worldwide in the oil, gas, and petroleum industries. This Quick Guide is unique in providing simple, accessible and well-structured guidance for anyone studying the API 510 Certified Pressure Vessel Inspector syllabus by summarizing and helping them through the syllabus and providing multiple example questions and worked answers.Technical standards are referenced from the API 'body of knowledge' for the examination, i.e. API 510 Pressure vessel inspection, alteration, rerating; API 572 Pressure vessel inspection; API

  16. A knowledge discovery object model API for Java

    Directory of Open Access Journals (Sweden)

    Jones Steven JM

    2003-10-01

    Full Text Available Abstract Background Biological data resources have become heterogeneous and derive from multiple sources. This introduces challenges in the management and utilization of this data in software development. Although efforts are underway to create a standard format for the transmission and storage of biological data, this objective has yet to be fully realized. Results This work describes an application programming interface (API that provides a framework for developing an effective biological knowledge ontology for Java-based software projects. The API provides a robust framework for the data acquisition and management needs of an ontology implementation. In addition, the API contains classes to assist in creating GUIs to represent this data visually. Conclusions The Knowledge Discovery Object Model (KDOM API is particularly useful for medium to large applications, or for a number of smaller software projects with common characteristics or objectives. KDOM can be coupled effectively with other biologically relevant APIs and classes. Source code, libraries, documentation and examples are available at http://www.bcgsc.ca/bioinfo/software.

  17. Thermodynamic phase behavior of API/polymer solid dispersions.

    Science.gov (United States)

    Prudic, Anke; Ji, Yuanhui; Sadowski, Gabriele

    2014-07-07

    To improve the bioavailability of poorly soluble active pharmaceutical ingredients (APIs), these materials are often integrated into a polymer matrix that acts as a carrier. The resulting mixture is called a solid dispersion. In this work, the phase behaviors of solid dispersions were investigated as a function of the API as well as of the type and molecular weight of the carrier polymer. Specifically, the solubility of artemisinin and indomethacin was measured in different poly(ethylene glycol)s (PEG 400, PEG 6000, and PEG 35000). The measured solubility data and the solubility of sulfonamides in poly(vinylpyrrolidone) (PVP) K10 and PEG 35000 were modeled using the perturbed-chain statistical associating fluid theory (PC-SAFT). The results show that PC-SAFT predictions are in a good accordance with the experimental data, and PC-SAFT can be used to predict the whole phase diagram of an API/polymer solid dispersion as a function of the kind of API and polymer and of the polymer's molecular weight. This remarkably simplifies the screening process for suitable API/polymer combinations.

  18. Dinámica del carbono (almacenes y flujos en manglares de México

    Directory of Open Access Journals (Sweden)

    Jorge A. Herrera Silveira

    2016-03-01

    Full Text Available La cobertura de los manglares de México los coloca en cuarto lugar a nivel mundial. Se reconocen sus múltiples servicios ecosistémicos, pero también altas tasas de deforestación. Evaluaciones en otras partes del mundo destacan el papel de los manglares en el ciclo del carbono, principalmente como almacenes de carbono orgánico (Corg en los sedimentos y exportadores de Corg disuelto y particulado. Para estimar la contribución de los manglares, a escala local, regional y de país, en estrategias como la Reducción de Emisiones por Deforestación y Degradación (REDD+, es indispensable determinar los almacenes de Corg como línea base de emisiones. En este estudio se realizó una búsqueda bibliográfica sobre almacenes y flujos de carbono en manglares de México mediante diferentes fuentes de información. De más de 200 estudios, solo 48 contenían datos o información para hacer una revisión del estado que guarda el conocimiento de almacenes y flujos de Corg en los manglares de México. Regionalmente, la zona del Pacífico Central tiene menos información y la Península de Yucatán donde más datos existen. Los mayores almacenes de Corg total se localizan en el Golfo de México y en los manglares de tipo ribereño (>1200 Mg C ha-1. Existe menos información sobre flujos de Corg, dominando los relacionados con la caída de hojarasca. En la zona del Pacífico Sur y en el manglar ribereño se observaron los valores más altos. La extensión y variabilidad de condiciones ambientales en los manglares de México son una oportunidad para desarrollar múltiples temas de investigación, como la caracterización de paisajes y mapas locales de coberturas relacionados con variables del agua (hidroperíodo, del suelo (topografía y procesos microbiológicos. La extensión y distribución de los manglares ofrecen la oportunidad para formar grupos de investigadores a escala regional y abordar de forma consensada estudios bajo una estrategia metodol

  19. Nosema ceranae in drone honey bees (Apis mellifera).

    Science.gov (United States)

    Traver, Brenna E; Fell, Richard D

    2011-07-01

    Nosema ceranae is a microsporidian intracellular parasite of honey bees, Apis mellifera. Previously Nosema apis was thought to be the only cause of nosemosis, but it has recently been proposed that N. ceranae is displacing N. apis. The rapid spread of N. ceranae could be due to additional transmission mechanisms, as well as higher infectivity. We analyzed drones for N. ceranae infections using duplex qPCR with species specific primers and probes. We found that both immature and mature drones are infected with N. ceranae at low levels. This is the first report detecting N. ceranae in immature bees. Our data suggest that because drones are known to drift from their parent hives to other hives, they could provide a means for disease spread within and between apiaries.

  20. Acinetobacter apis sp. nov., isolated from the intestinal tract of a honey bee, Apis mellifera.

    Science.gov (United States)

    Kim, Pil Soo; Shin, Na-Ri; Kim, Joon Yong; Yun, Ji-Hyun; Hyun, Dong-Wook; Bae, Jin-Woo

    2014-08-01

    A novel Gram-negative, obligate aerobic, non-motile, and both coccobacillus- and bacillus-shaped bacterium, designated strain HYN18(T), was isolated from the intestinal tract of a honey bee (Apis mellifera). The isolate was oxidase-negative and catalase-positive. Strain HYN18(T) showed optimum growth at 25°C, pH 6-7, and in the presence of 1% (w/v) NaCl in trypticase soy broth medium. The isolate was negative for hydrolyses of starch, casein, gelatin and urea, indole production from tryptone and hemolysis on sheep blood agar. A phylogenetic analysis based on the 16S rRNA gene and rpoB gene sequence showed that strain HYN18(T) was most closely related to Acinetobacter nectaris SAP 763.2(T) and A. boissieri SAP 284.1(T) with 98.3% and 98.1% similarity (16S rRNA gene), respectively, and 84.4% similarity with Acinetobacter nectaris SAP 763.2(T) (rpoB gene). The major cellular fatty acids were summed features 3 (comprising C16:1ω7c /C16:1ω6c ), C12:0 and C16:0. The main isoprenoid quinone was ubiquinone-9 (Q-9). The polar lipids of strain HYN18(T) were phosphatidylethanolamine, three unidentified lipids, an unidentified phospholipid and an unidentified glycolipid. The DNA G+C content was 40.6 mol%. DNA-DNA hybridization experiments indicated less than 33 ± 10% relatedness to the closest phylogenetic species, Acinetobacter nectaris SAP 763.2(T). Thus, the phenotypic, phylogenetic and genotypic analyses indicate that strain HYN18(T) is a novel species within the genus Acinetobacter, for which the name Acinetobacter apis is proposed. The type strain is HYN18(T) (=KACC 16906(T) =JCM 18575(T)).

  1. Efecto del vanadio en la forja en tibio de un acero con contenido medio de carbono

    Directory of Open Access Journals (Sweden)

    García-Mateo, C.

    1998-05-01

    Full Text Available In the present work the influence of vanadium on the microstructure and mechanical properties of a medium carbon steel forged below 900°C is analysed. Undisolved V(CN refines the microstructure and together with reprecipitated particles during cooling contribute to strengthening. Both effects maintain mechanical strength levels without decreasing toughness values.

    En el presente trabajo se analiza la influencia del vanadio en la microestructura y en la resistencia mecánica de un acero con contenido medio de carbono, tras ser deformado por compresión plana a temperaturas inferiores a 900°C. Los carbonitruros de vanadio no disueltos afinan la microestructura y junto a los reprecipitados durante el enfriamiento contribuyen al endurecimiento por precipitación, manteniendo la resistencia mecánica y logrando una tenacidad aceptable al bajar la temperatura de deformación.

  2. The global warming, public goods and carbon market; Calentamiento global, bienes publicos y mercado de carbono

    Energy Technology Data Exchange (ETDEWEB)

    Quadri de la Torre, Gabriel [EcoSecurities (Mexico)

    2007-07-15

    The global warming is an issue of the public goods, and demands an outstanding multilateral action, which must to ensure both efficiency and unchanging transition towards an economy of low intensity of carbon. The new system, which is going to replace the Kyoto Protocol, will have compromises for the developing countries and deep implication in the relative competitivity of the nations and companies. [Spanish] El calentamiento global es un problema de bienes publicos que exige una extraordinaria accion multilateral. Esta debe asegurar eficiencia y una transicion fluida hacia una economia de baja intensidad de carbono. El nuevo sistema que sucedera al Protocolo de Kyoto significara compromisos para los paises en vias de desarrollo, y tendra profundas implicaciones en la competitividad relativa de naciones y empresas.

  3. La Dieta del Dióxido de Carbono (CO2

    Directory of Open Access Journals (Sweden)

    Jorge Medina Valtierra

    2010-01-01

    Full Text Available Hoy en día y frecuentemente estamos viviendo el incremento de los desastres naturales en nuestro planeta y además sabemos que esto se debe al fenómeno llamado calentamiento global. Si este fenómeno continúa en aumento, muy pronto se tendrá un resultado devastador en el clima de la Tierra, aún para un aumento global de tan solo 2 ºC en un tiempo corto. El dióxido de carbono (CO2 es un importante contaminante cuya concentración aumenta y contribuye notablemente a tal sistema anómalo. Pero, un aumento en la temperatura del aire incrementará también la cantidad de vapor de agua en la atmósfera, añadiendo con esto más "fuego" al fenómeno señalado.

  4. Carbon Bonds and the saving of energy; Bonos de carbono y el ahorro de energia

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez Ramirez, Alejandro [NovaEnergia (Mexico)

    2005-07-01

    This document deals with the development of the carbon bond project, the energy saving and the entry into force of the Kyoto Protocol at a world-wide level. In this project Mexico opts for a development model in which the economic growth brakes ties with the discharge of greenhouse effect gases and in which the progress does not mean more damages to our planet. [Spanish] Este documento trata sobre el desarrollo del proyecto de bonos de carbono, ahorro de energia y la entrada en vigor del Protocolo de Kyoto a nivel mundial, en el cual Mexico opta por un modelo de desarrollo en el que el crecimiento economico esta desvinculado de la emision de gases de efecto invernadero y en donde el progreso no signifique mas danos a nuestro planeta.

  5. Selección automatizada de electrodos para la soldadura manual de los aceros al carbono

    Directory of Open Access Journals (Sweden)

    Alexander Velázquez Font

    2008-01-01

    Full Text Available Se aborda lo relativo a un sistema para la selección automatizada de electrodos en la soldadura de los aceros al carbono. Se inicia con una breve revisión de los problemas que presentan estos en su soldabilidad y los factores concernientes a la selección correcta del electrodo en los mismos. En el mismo se expone el fundamento teórico sobre el diseño del sistema el cual da solución a lo anteriormente expuesto. En la elaboración del software se tiene en cuenta los siguientes principios: propiedades mecánicas de la unión soldada, tipo de revestimiento, posición de la soldadura, etc. Se tienen en cuenta en el trabajo diferentes firmas y normas de fabricantes de electrodos y países que mas se utilizan en la industria mecánica en Cuba. El software tiene la ventaja de ser sencillo, rápido y seguro, garantizando la selección correcta de los electrodos para cada caso y situación. El software supone que el usuario no tenga que tener conocimientos profundos de soldadura, debido a que el sistema se encarga de la mayor parte de las decisiones para la selección del electrodo, procedimiento que con métodos convencionales, exigen del usuario una determinada experiencia en la selección de estos materiales para la soldadura de los aceros al carbono.

  6. Formas de carbono orgánico en suelos con diferentes usos en el departamento del Magdalena (Colombia

    Directory of Open Access Journals (Sweden)

    José Rafael Vásquez-Polo

    2011-12-01

    Full Text Available Las fracciones de materia orgánica del suelo (MOS lábiles y humificadas pueden ser afectadas por las prácticas de uso y manejo; sin embargo el impacto de estos cambios no se ha evaluado en suelos y ambientes tropicales. El presente estudio tuvo como objetivo evaluar los contenidos y algunas formas de carbono orgánico del suelo (COS en cinco zonas de clima cálido tropical (0 - 1110 m.s.n.m. del departamento del Magdalena (Colombia y el efecto que sobre ellas han tenido las prácticas asociadas a suelos cultivados con café (Coffea arabica, banano (Musa sp., palma africana (Elaeis guineensis y sábila (Aloe vera, comparados con suelos de bosques naturales. No se encontraron diferencias (P < 0.05 tanto entre zonas como entre usos del suelo, se presentaron valores medios a bajos de MOS en las zonas de estudio y contenidos de carbono total (Ct mayores en suelos de bosques que en suelos cultivados, así los suelos de bosques presentan una acumulación media de Ct de 42.4 mg/ha a 20 cm, frente a 33.8 mg/ha en los suelos cultivados, esto equivale a una pérdida media de Ct del 23% por efecto del manejo de los cultivos. En relación con el carbono extraíble con pirofosfato sódico altamente relacionado con las fracciones humificadas de la MOS (Cp se observaron valores muy bajos en los suelos cultivados y casi nulos en suelos de bosques; sin embargo estos últimos presentan mayor contenido de formas de carbono no-oxidables o estables (Cnox determinado por diferencia entre Ct - carbono oxidable (Cox. En el suelo cultivado con banano, el Ct corresponde en su totalidad a formas de Cox; mientras que en el suelo cultivado con palma africana las formas estables Cnox representaron 83% del carbono total.

  7. Formas de carbono orgánico en suelos con diferentes usos en el departamento del Magdalena (Colombia

    Directory of Open Access Journals (Sweden)

    Menjivar Flores Juan Carlos

    2011-12-01

    Full Text Available Las fracciones de materia orgánica del suelo (MOS lábiles y humificadas pueden ser afectadas por las prácticas de uso y manejo; sin embargo el impacto de estos cambios no se ha evaluado en suelos y ambientes tropicales. El presente estudio tuvo como objetivo evaluar los contenidos y algunas formas de carbono orgánico del suelo (COS en cinco zonas de clima cálido tropical (0 - 1110 m.s.n.m. del departamento del Magdalena (Colombia y el efecto que sobre ellas han tenido las prácticas asociadas a suelos cultivados con café (Coffea arabica, banano (Musa sp., palma africana (Elaeis guineensis y sábila (Aloe vera, comparados con suelos de bosques naturales. No se encontraron diferencias (P < 0.05 tanto entre zonas como entre usos del suelo, se presentaron valores medios a bajos de MOS en las zonas de estudio y contenidos de carbono total (Ct mayores en suelos de bosques que en suelos cultivados, así los suelos de bosques presentan una acumulación media de Ct de 42.4 mg/ha a 20 cm, frente a 33.8 mg/ha en los suelos cultivados, esto equivale a una pérdida media de Ct del 23% por efecto del manejo de los cultivos. En relación con el carbono extraíble con pirofosfato sódico altamente relacionado con las fracciones humificadas de la MOS (Cp se observaron valores muy bajos en los suelos cultivados y casi nulos en suelos de bosques; sin embargo estos últimos presentan mayor contenido de formas de carbono no-oxidables o estables (Cnox determinado por diferencia entre Ct - carbono oxidable (Cox. En el suelo cultivado con banano, el Ct corresponde en su totalidad a formas de Cox; mientras que en el suelo cultivado con palma africana las formas estables Cnox representaron 83% del carbono total.

  8. Sperm use economy of honeybee (Apis mellifera) queens

    DEFF Research Database (Denmark)

    Baer, Boris; Collins, Jason; Maalaps, Kristiina;

    2016-01-01

    the fecundity and longevity of queens and therefore colony fitness. We quantified the number of sperm that honeybee (Apis mellifera) queens use to fertilize eggs. We examined sperm use in naturally mated queens of different ages and in queens artificially inseminated with different volumes of semen. We found...

  9. Standard methods for research on apis mellifera gut symbionts

    Science.gov (United States)

    Gut microbes can play an important role in digestion, disease resistance, and the general health of animals, but little is known about the biology of gut symbionts in Apis mellifera. This paper is part of a series on honey bee research methods, providing protocols for studying gut symbionts. We desc...

  10. The Proteins API: accessing key integrated protein and genome information.

    Science.gov (United States)

    Nightingale, Andrew; Antunes, Ricardo; Alpi, Emanuele; Bursteinas, Borisas; Gonzales, Leonardo; Liu, Wudong; Luo, Jie; Qi, Guoying; Turner, Edd; Martin, Maria

    2017-04-05

    The Proteins API provides searching and programmatic access to protein and associated genomics data such as curated protein sequence positional annotations from UniProtKB, as well as mapped variation and proteomics data from large scale data sources (LSS). Using the coordinates service, researchers are able to retrieve the genomic sequence coordinates for proteins in UniProtKB. This, the LSS genomics and proteomics data for UniProt proteins is programmatically only available through this service. A Swagger UI has been implemented to provide documentation, an interface for users, with little or no programming experience, to 'talk' to the services to quickly and easily formulate queries with the services and obtain dynamically generated source code for popular programming languages, such as Java, Perl, Python and Ruby. Search results are returned as standard JSON, XML or GFF data objects. The Proteins API is a scalable, reliable, fast, easy to use RESTful services that provides a broad protein information resource for users to ask questions based upon their field of expertise and allowing them to gain an integrated overview of protein annotations available to aid their knowledge gain on proteins in biological processes. The Proteins API is available at (http://www.ebi.ac.uk/proteins/api/doc).

  11. Fertile diploid drones in africanized honeybees, Apis mellifera adansonii.

    Science.gov (United States)

    Chaud-Netto, J

    1977-02-15

    59 diploid drones of Apis mellifera adansonii, 12-37 days old, were tested for the presence of semen after provoked ejaculation; 13 drones ejaculated semen enough to be used in an instrumental insemination, but only three on them (5%) furnished 1 mm3 of semen. The problems referring to the attainment of descendants from the 2n drones are briefly discussed.

  12. The MPO API: A tool for recording scientific workflows

    Energy Technology Data Exchange (ETDEWEB)

    Wright, John C., E-mail: jcwright@mit.edu [MIT Plasma Science and Fusion Center, Cambridge, MA (United States); Greenwald, Martin; Stillerman, Joshua [MIT Plasma Science and Fusion Center, Cambridge, MA (United States); Abla, Gheni; Chanthavong, Bobby; Flanagan, Sean; Schissel, David; Lee, Xia [General Atomics, San Diego, CA (United States); Romosan, Alex; Shoshani, Arie [Lawrence Berkeley Laboratory, Berkeley, CA (United States)

    2014-05-15

    Highlights: • A description of a new framework and tool for recording scientific workflows, especially those resulting from simulation and analysis. • An explanation of the underlying technologies used to implement this web based tool. • Several examples of using the tool. - Abstract: Data from large-scale experiments and extreme-scale computing is expensive to produce and may be used for high-consequence applications. The Metadata, Provenance and Ontology (MPO) project builds on previous work [M. Greenwald, Fusion Eng. Des. 87 (2012) 2205–2208] and is focused on providing documentation of workflows, data provenance and the ability to data-mine large sets of results. While there are important design and development aspects to the data structures and user interfaces, we concern ourselves in this paper with the application programming interface (API) – the set of functions that interface with the data server. Our approach for the data server is to follow the Representational State Transfer (RESTful) software architecture style for client–server communication. At its core, the API uses the POST and GET methods of the HTTP protocol to transfer workflow information in message bodies to targets specified in the URL to and from the database via a web server. Higher level API calls are built upon this core API. This design facilitates implementation on different platforms and in different languages and is robust to changes in the underlying technologies used. The command line client implementation can communicate with the data server from any machine with HTTP access.

  13. PrismTech Data Distribution Service Java API Evaluation

    Science.gov (United States)

    Riggs, Cortney

    2008-01-01

    My internship duties with Launch Control Systems required me to start performance testing of an Object Management Group's (OMG) Data Distribution Service (DDS) specification implementation by PrismTech Limited through the Java programming language application programming interface (API). DDS is a networking middleware for Real-Time Data Distribution. The performance testing involves latency, redundant publishers, extended duration, redundant failover, and read performance. Time constraints allowed only for a data throughput test. I have designed the testing applications to perform all performance tests when time is allowed. Performance evaluation data such as megabits per second and central processing unit (CPU) time consumption were not easily attainable through the Java programming language; they required new methods and classes created in the test applications. Evaluation of this product showed the rate that data can be sent across the network. Performance rates are better on Linux platforms than AIX and Sun platforms. Compared to previous C++ programming language API, the performance evaluation also shows the language differences for the implementation. The Java API of the DDS has a lower throughput performance than the C++ API.

  14. The Automatic Start Method of Application Program Using API

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    This paper introduces on a method about the au-tomactic start of application program. Through defining Registryby API function, the automatic start of specified application pro-gram is fulfilled when Windows98 is taking action. It gives facil-ities to many computer application works.

  15. Modelling the subgenual organ of the honeybee, Apis mellifera

    DEFF Research Database (Denmark)

    Storm, Jesper; Kilpinen, Ole

    1998-01-01

    In a recent study on the honeybee (Apis mellifera), the subgenual organ was observed moving inside the leg during sinusoidal vibrations of the leg (Kilpinen and Storm 1997). The subgenual organ of the honeybee is suspended in a haemolymph channel in the tibia of each leg. When the leg accelerates...

  16. Equações alométricas para estimativa de carbono em árvores de uma área urbana em Viçosa-MG

    Directory of Open Access Journals (Sweden)

    Daniel Brianezi

    2013-12-01

    Full Text Available Objetivou-se com este estudo gerar equações para estimar o carbono presente na arborização do campus-sede da Universidade Federal de Viçosa, contribuindo para o conhecimento sobre a capacidade das áreas verdes urbanas no sequestro e estocagem de carbono. Assim, inventariaram-se todas as árvores com DAP igual ou superior a 5 cm presentes na Universidade. Para as árvores não palmeiras, selecionaram-se 721 árvores-amostra, que foram cubadas rigorosamente em pé através da aplicação sucessiva da expressão de Smalian até o diâmetro-limite de 5 cm, tanto para o fuste quanto para os galhos. No caso das palmeiras, cubaram-se 100% dos indivíduos utilizando a expressão de Huber. A densidade básica da madeira com casca e o teor de carbono foram obtidos, nas palmeiras, com a retirada de um disco na porção do DAP, dada a dificuldade de tradagem. Já nas demais árvores, utilizou-se um trado mecânico. Com base no volume, na densidade básica e no teor de carbono, calcularam-se o carbono total e o carbono dos galhos. Ademais, avaliaram-se os modelos de Schumacher e Hall (1933 e Spurr (1952, modificado para estimar o carbono fixado nesses indivíduos. Nas árvores não palmeiras do campus-sede da Universidade Federal de Viçosa, o carbono total e o carbono dos galhos podem ser estimados, em kg, em razão do Diâmetro à Altura do Peito (DAP, em cm e da Altura Total (Ht, em m, por -0,906586+1,60421*LnDAP+0,37162*LnHt e por -2,052673+1,89903*LnDAP+0,24156*LnHt, respectivamente. Nas palmeiras, o carbono total pode ser estimado por -4,46988+199082*LnDAP+1,06420*LnHt.

  17. Evaluación de la susceptibilidad a la corrosión por picado del acero API 5L x42 expuesto a un ambiente con cloruros y CO2 mediante la técnica de ruido electroquímico

    Directory of Open Access Journals (Sweden)

    Rodríguez-Vanegas, N.

    2011-10-01

    Full Text Available The concentration of chloride ions and the partial pressure of CO2 play an important role in the degradation of low-carbon steels used for the construction of pipelines in oil and gas industry. In order to evaluate the susceptibility of carbon steel API 5L X42 to pitting corrosion electrochemical noise and linear polarization resistance measurements were carried out in aqueous solutions containing chloride ions and CO2. The concentration of chloride ions was varied between, 10000 and 18000 ppm, and the CO2 partial pressure between 10 psi and 18 psi. Experimental results pointed out that the formation of protective layer, consisting mainly of FeCO 3, depends on the partial pressure of CO2 in the system. Nevertheless, the stability of this layer was considerably affected by increasing the concentration of chloride ions causing that localized corrosion has taken place in some areas of the surface of API 5L X42, which were detected by electrochemical noise echnique.La concentración de iones cloruro y la presión parcial de CO2, tienen un papel importante en el proceso de degradación de los aceros de bajo carbono empleados en la construcción de líneas de transporte en industrias petroleras. Con el fin de evaluar la susceptibilidad del acero al carbono API 5L X42 a la corrosión por picado, se realizaron medidas de ruido electroquímico y resistencia a la polarización lineal en soluciones acuosas de iones cloruro con concentraciones entre 10.000 y 18.000 ppm, variando la presión parcial de CO2 entre 10 psi y 18 psi. Los resultados indican que la formación de una capa protectora, constituida principalmente por FeCO3, depende de la presión parcial de CO2 del sistema. No obstante, la estabilidad de dicha capa es afectada significativamente por el aumento de la concentración de iones cloruro, que producen fenómenos de corrosión localizada en algunas áreas de la superficie del acero API 5L X42, los cuales fueron detectados por la técnica de

  18. Reserva de carbono en biomasa forestal y suelos minerales en el Parque Nacional Malinche (México

    Directory of Open Access Journals (Sweden)

    María Eugenia Valdez Pérez

    2016-01-01

    Full Text Available Las áreas naturales protegidas representan una de las estrategias para la mitigación del cambio climático. El objetivo de esta investigación consistió en estimar el contenido de carbono en biomasa forestal en suelos minerales y calcular las pérdidas de carbono por cambios de uso del suelo en el Parque Nacional Malinche (PNM. La superficie de bosque del PNM es de 17.496,34 ha y almacena 1.544.377,66 mg en bosque y 4.148.985,97 mg en suelos. Para estimar el contenido de biomasa forestal se aplicaron ecuaciones alométricas y se trabajó con la cartografía del Instituto Nacional de Estadística y Geografía (INEGI en el análisis espacio-temporal de los cambios de uso de suelo. Para el carbono en suelos se aplicaron los valores del Panel Intergubernamental de Cambio Climático (IPCC.

  19. Comportamiento del monóxido de carbono y el clima en la ciudad de Toluca, de 1995 a 2001

    Directory of Open Access Journals (Sweden)

    Julio César Hernández Romero

    2004-01-01

    Full Text Available Uno de los gases contaminantes con mayor distribución y concentración en Toluca y su área metropolitana es el monóxido de carbono que, al igual que el dióxido de azufre y el dióxido de carbono, es generado principalmente por la combustión automotriz y, en segundo lugar por el sector industrial. Sin embargo, debido a la activa dinámica de los vientos en la mayor parte del año, estos gases tienden a dispersarse en todo el valle; solamente durante el invierno la concentración y la distribución del monóxido de carbono se encuentran por encima de las normas establecidas en la legislación vigente. Por eso se considera la calidad del aire como satisfactoria, aunque por su combinación con las bajas temperaturas del periodo invernal y la baja humedad del aire, tiende a representar riesgos para la salud humana.

  20. Solubilização de fostatos por microrganismos na presença de fontes de carbono

    Directory of Open Access Journals (Sweden)

    G. N. Silva Filho

    2000-06-01

    Full Text Available O potencial de solubilização de fosfatos por bactérias e fungos cultivados em meio de cultura GEL (Glicose-Extrato de Levedura, suplementado com diferentes formas de fosfatos (cálcio, alumínio e ferro e fontes de carbono (celulose, amido, sacarose, glicose, frutose e xilose, foi avaliado em laboratório. O crescimento, o diâmetro da área solubilizada e a relação halo/colônia variaram conforme o tipo de microrganismo e a fonte de fósforo e de carbono. Dos 57 isolados utilizados, 56 formaram halo na presença de fosfato de cálcio e cinco apenas na presença de fosfato de alumínio e nenhum foi capaz de solubilizar fosfato de ferro. Contudo, seis isolados cresceram melhor no meio com fosfato de ferro em comparação com o meio testemunha. As maiores colônias e halos foram observados nos isolados de Rhizopus e Aspergillus, enquanto as maiores relações halo/colônia foram encontradas em Paecilomyces e Penicillium. Todos os isolados cresceram no meio GEL base (testemunha sem açúcar, mas a solubilização ocorreu apenas na presença de carbono adicionado ao meio, destacando-se xilose, glicose, frutose e sacarose.

  1. EXPERIENCE API – NEW STANDARD OF E-LEARNING SOFTWARE AND EXAMPLES OF ITS PRACTICAL USE

    Directory of Open Access Journals (Sweden)

    Oleksandr A. Shcherbyna

    2016-07-01

    Full Text Available The purpose of the article is to analyze features of the new standard of e-learning software - Experience API (xAPI, previously also known as the Tin Can API. The standard defines a way of interaction between xAPI-clients – software which students work with while e-learning process, and xAPI-servers – Learning Record Stores (LRS, which store data about their results. Standard also defines LRS data representation format and a way of data transfers between LRS, which makes it possible to combine several LRS into distributed database that could accumulate information about people training in formal, non-formal and informal education throughout life. The article contains review of available xAPI-clients, xAPI-servers, and the results of their testing, which prove the possibility of their usage in our educational institutions.

  2. Host Specificity in the Honeybee Parasitic Mite, Varroa spp. in Apis mellifera and Apis cerana.

    Directory of Open Access Journals (Sweden)

    Alexis L Beaurepaire

    Full Text Available The ectoparasitic mite Varroa destructor is a major global threat to the Western honeybee Apis mellifera. This mite was originally a parasite of A. cerana in Asia but managed to spill over into colonies of A. mellifera which had been introduced to this continent for honey production. To date, only two almost clonal types of V. destructor from Korea and Japan have been detected in A. mellifera colonies. However, since both A. mellifera and A. cerana colonies are kept in close proximity throughout Asia, not only new spill overs but also spill backs of highly virulent types may be possible, with unpredictable consequences for both honeybee species. We studied the dispersal and hybridisation potential of Varroa from sympatric colonies of the two hosts in Northern Vietnam and the Philippines using mitochondrial and microsatellite DNA markers. We found a very distinct mtDNA haplotype equally invading both A. mellifera and A. cerana in the Philippines. In contrast, we observed a complete reproductive isolation of various Vietnamese Varroa populations in A. mellifera and A. cerana colonies even if kept in the same apiaries. In light of this variance in host specificity, the adaptation of the mite to its hosts seems to have generated much more genetic diversity than previously recognised and the Varroa species complex may include substantial cryptic speciation.

  3. Changes in Alternative Splicing in Apis Mellifera Bees Fed Apis Cerana Royal Jelly

    Directory of Open Access Journals (Sweden)

    Shi Yuan Yuan

    2014-12-01

    Full Text Available The Western honey bee (Apis mellifera is a social insect characterized by caste differentiation in which the queen bee and worker bees display marked differences in morphology, behavior, reproduction, and longevity despite their identical genomes. The main causative factor in caste differentiation is the food fed to queen larvae, termed royal jelly (RJ. Alternative splicing (AS is an important RNA-mediated post-transcriptional process in eukaryotes. Here we report AS changes in A. mellifera after being fed either A. mellifera RJ or A. cerana RJ. The results demonstrated that the RJ type affected 4 types of AS in adult A. mellifera: exon skipping, intron retention, alternative 5’ splice sites, and alternative 3’splice sites. After feeding with A. cerana RJ, AS occurred in many genes in adult A. mellifera that encode proteins involved in development, growth, the tricarboxylic acid cycle, and substance metabolism. This study provides the first evidence that heterospecific RJ can influence the AS of many genes related to honey bee development and growth.

  4. Host Specificity in the Honeybee Parasitic Mite, Varroa spp. in Apis mellifera and Apis cerana.

    Science.gov (United States)

    Beaurepaire, Alexis L; Truong, Tuan A; Fajardo, Alejandro C; Dinh, Tam Q; Cervancia, Cleofas; Moritz, Robin F A

    2015-01-01

    The ectoparasitic mite Varroa destructor is a major global threat to the Western honeybee Apis mellifera. This mite was originally a parasite of A. cerana in Asia but managed to spill over into colonies of A. mellifera which had been introduced to this continent for honey production. To date, only two almost clonal types of V. destructor from Korea and Japan have been detected in A. mellifera colonies. However, since both A. mellifera and A. cerana colonies are kept in close proximity throughout Asia, not only new spill overs but also spill backs of highly virulent types may be possible, with unpredictable consequences for both honeybee species. We studied the dispersal and hybridisation potential of Varroa from sympatric colonies of the two hosts in Northern Vietnam and the Philippines using mitochondrial and microsatellite DNA markers. We found a very distinct mtDNA haplotype equally invading both A. mellifera and A. cerana in the Philippines. In contrast, we observed a complete reproductive isolation of various Vietnamese Varroa populations in A. mellifera and A. cerana colonies even if kept in the same apiaries. In light of this variance in host specificity, the adaptation of the mite to its hosts seems to have generated much more genetic diversity than previously recognised and the Varroa species complex may include substantial cryptic speciation.

  5. Cogeneration and Carbon bonds: clean development; Cogeneracion y bonos de carbono: desarrollo limpio

    Energy Technology Data Exchange (ETDEWEB)

    Navarro Perez, Nidia [Facultad de Contaduria y Administracion, Universidad Nacional Autonoma de Mexico, Mexico, D.F. (Mexico)

    2004-06-15

    The growing preoccupation for the environment in our country and its interest to ratify the Kyoto Protocol with respect to the contamination of the atmosphere, offers great opportunities for the cogeneration so that it fortifies the scientific and technological research and gives a good international image about the sustainable development and care of the environment, so that companies that invest in clean technology will be able to assign a monetary value to their environmental patrimony, this through the so called Green Bonds or Carbon Bonds, this opens a new dimension to finance projects by means of these bonds that can be negotiated at an international level; by means of the Clean of Energy Production the investment can be stimulated and revenues for projects that contribute to the sustainable development of the country and the power efficiency. At the moment the country has at least 13 projects in different analysis stages to enter the carbon bond market, which are presented as co-generation projects of energy, in addition to the formation of the Mexican Committee for Projects of Reduction and Capture of Gas Discharges of Greenhouse Effect. [Spanish] La creciente preocupacion por el medio ambiente en nuestro pais y su interes por ratificar el Protocolo de Kyoto en lo referente a la contaminacion de la atmosfera, ofrece grandes oportunidades para la cogeneracion de manera que fortalezca la investigacion cientifica y tecnologica y dar una buena imagen internacional en torno a temas de desarrollo sustentable y cuidado del medio ambiente, de manera que empresas que invierten en tecnologia limpia podran asignar un valor monetario a su patrimonio ambiental, esto a traves de los llamados Bonos Verdes o Bonos de Carbono, esto abre una dimension nueva para financiar proyectos por medio de estos bonos que pueden negociarse a nivel internacional; por medio de la Produccion Limpia de energia se puede estimular inversion y ganancias para proyectos que contribuyan al

  6. ANÁLISE ISOTÓPICA DO CARBONO EM NÉCTARES DE CAJU

    Directory of Open Access Journals (Sweden)

    Ricardo FIGUEIRA

    2011-12-01

    Full Text Available Os objetivos deste trabalho foram determinar a composição isotópica de néctares comerciais de caju e, por meio de modelos de mistura, quantificar aporcentagem de carbono proveniente de plantas do ciclo fotossintético C3 , a fim de identificar as bebidas que não estavam em conformidade com as normas do Ministério da Agricultura, Pecuária e Abastecimento (MAPA. Para isso, foram produzidos néctares em laboratório conforme a legislação brasileira. Também foi produzida bebida adulterada com quantidade de polpa de caju abaixo do limite estabelecido. Nesses néctares, as porcentagens teóricas de fonte C3 foram calculadas por meio do balanço de massa de sólidos solú- veis. Para a análise isotópica foram mensurados os valores isotópicos dos açúcares de cana, dos néctares de caju e de suas frações açúcares purificados e sólidos insolúveis. Com esses valores, foram calculadas as porcentagens práticas de fonte C3 (reais por meio da análise isotópica, em espectrô- metro de massa. Os resultados práticos foram comparados com os teóricos para definir a melhor forma de quantifi- cação de fonte C3 . Para identificar os néctares comerciais adulterados, foi desenvolvido um limite de legalidade conforme a legislação brasileira. Quatro marcas de néctares de caju foram analisadas e todas classificadas como legais. O limite de legalidade possibilitou identificar as bebidas em conformidade com a lei. A metodologia foi eficiente para quantificar o carbono de origem C3 em néctares comerciais de caju.

  7. Almacén y dinámica del carbono orgánico del suelo en bosques templados de México

    Directory of Open Access Journals (Sweden)

    Leopoldo Galicia

    2016-03-01

    Full Text Available Los bosques templados se establecen sobre diversos tipos de suelo, sin embargo la información sobre las características físicas, químicas y biológicas de estos suelos y su influencia en el ciclo del carbono es escasa. El objetivo de la presente revisión fue conocer el almacenamiento de carbono en suelos cubiertos por bosques templados. Estos bosques se distribuyen sobre 23 tipos de suelo, principalmente Leptosoles, Regosoles, Luvisoles, Phaeozems, Cambisoles, Umbrisoles y Andosoles formados a partir de materiales volcánicos en el centro del país, sedimentarios en la Sierra Madre Oriental y una variedad amplia de sustratos en la Sierra Madre Occidental. La información sobre el potencial de captura de carbono en los bosques templados está sesgada a la biomasa aérea; y existe menos información sobre los almacenes de carbono edáficos y un escaso entendimiento de los procesos de su estabilización. El almacenamiento de carbono del suelo varió con el tipo de suelo, la composición de especies y el relieve. Los Andosoles, a pesar de su escasa abundancia, son los suelos con la mayor capacidad de almacenar carbono debido a sus características mineralógicas. Los cambios en el carbono orgánico del suelo y los flujos de carbono en los bosques templados en México son el resultado de cambios locales, generados por las actividades humanas como el cambio de uso, el manejo forestal, los incendios, la regeneración y la sustitución de especies. El cambio de uso de suelo es uno de los principales factores que explican los flujos de carbono en estos ecosistemas, sin embargo, aún no existe evidencia clara de que sea en sentido negativo. Esta revisión resume la información existente y propone investigaciones futuras que permitan conocer mejor los procesos de estabilización de la materia orgánica en los suelos de bosques templados.

  8. Infra-population and -community dynamics of the parasites Nosema apis and Nosema ceranae, and consequences for honey bee (Apis mellifera hosts.

    Directory of Open Access Journals (Sweden)

    Geoffrey R Williams

    Full Text Available Nosema spp. fungal gut parasites are among myriad possible explanations for contemporary increased mortality of western honey bees (Apis mellifera, hereafter honey bee in many regions of the world. Invasive Nosema ceranae is particularly worrisome because some evidence suggests it has greater virulence than its congener N. apis. N. ceranae appears to have recently switched hosts from Asian honey bees (Apis cerana and now has a nearly global distribution in honey bees, apparently displacing N. apis. We examined parasite reproduction and effects of N. apis, N. ceranae, and mixed Nosema infections on honey bee hosts in laboratory experiments. Both infection intensity and honey bee mortality were significantly greater for N. ceranae than for N. apis or mixed infections; mixed infection resulted in mortality similar to N. apis parasitism and reduced spore intensity, possibly due to inter-specific competition. This is the first long-term laboratory study to demonstrate lethal consequences of N. apis and N. ceranae and mixed Nosema parasitism in honey bees, and suggests that differences in reproduction and intra-host competition may explain apparent heterogeneous exclusion of the historic parasite by the invasive species.

  9. Secuestro de carbono en la biomasa aérea de un sistema agrosilvopastoril de Cocos nucifera, Leucaena leucocephala Var. Cunningham y Pennisetum purpureum Cuba CT-115

    Directory of Open Access Journals (Sweden)

    J. M. Anguiano

    2013-01-01

    Full Text Available Con el objetivo de estimar el secuestro de carbono en la biomasa aérea de un sistema agrosilvopastoril (sasp compuesto por cocotero (Cocos nucifera, Leucaena leucocephala Var. Cunningham sembrada en alta densidad y Pennisetum purpureum Cuba CT-115, se llevó a cabo un estudio en un suelo con textura franco arcillo- arenosa. Se utilizó un diseño en bloques al azar con arreglo en parcelas divididas con cuatro tratamientos 0, 40, 60 y 80 mil árboles de leucaena ha-1 y tres repeticiones; la evaluación duró desde su establecimiento hasta 340 días de edad. Los resultados muestran diferencia estadística (P<0.001 en el secuestro de carbono con 101.19d, 109.73c, 122.00b y 128.62a t C+ha-1año-1 para los sasp de 0, 40, 60 y 80 mil plantas de leucaena ha-1, respectivamente. El mayor aporte de secuestro de carbono lo realizó el cocotero que aportó del 60 al 80% del total del sasp y existió una relación inversa de secuestro de carbono de la gramínea al incrementar la densidad de la leguminosa. El tratamiento que incorpora la siembra en alta densidad de la leguminosa arbórea logró un mayor secuestro de carbono.

  10. PREPARACIÓN DE CATALIZADORES DE HIERRO Y COBALTO SOPORTADOS EN AEROGELES DE CARBONO

    Directory of Open Access Journals (Sweden)

    Ingrid Y. Aguilar

    2010-09-01

    Full Text Available Se prepararon catalizadores de hierro y cobalto, soportados en aerogeles de carbono (AGC, por los métodos de humedad incipiente, intercambio catiónico y adición de una sal del metal a la mezcla precursora de los aerogeles. La caracterización de los catalizadores se realizó por adsorción de N2 a 77 K, descomposición con temperatura programada (DTP y difracción de rayos X (DRX. Se encontró que los catalizadores preparados por humedad incipiente e intercambio catiónico tienen una textura microporosa, mientras que los preparados por adición de la sal del metal a la mezcla inicial son mesoporosos. Los resultados de DTP muestran que la química superficial del aerogel está influida por el método de preparación y la naturaleza química del metal, y los análisis de DRX pusieron en evidencia que la matriz carbonosa de los aerogeles tiene un carácter reductor capaz de carburizar o reducir el metal incorporado.

  11. Nanotubos de carbono aplicados às neurociências: perspectivas e desafios

    Directory of Open Access Journals (Sweden)

    Virginia Oliveira

    2011-01-01

    Full Text Available INTRODUÇÃO: Os nanotubos de carbono (NTCs são os nanomateriais mais promissores para aplicação terapêutica em doenças neurodegenerativas. Aplicações potenciais incluem sistemas de liberação controlada de fármacos, interfaces elétricas e substratos para crescimento celular. OBJETIVO: Descrever o estado da arte e as perspectivas e desafios da aplicação dos NTCs nas neurociências. MÉTODO: Procedeu-se a uma busca sistemática nos indexadores Medline, Lilacs e SciELO, utilizando os descritores "carbon nanotubes", "drug delivery", "electrical interface", "tissue regeneration", "neuroscience", "biocompatibility" e "nanotechnology", devidamente agrupados. RESULTADOS: A revisão da literatura evidenciou controvérsias nos estudos relativos à biocompatibilidade dos NTCs, embora tenha ratificado o seu potencial para a neuromedicina e neurociências. CONCLUSÃO: Os dados obtidos apontam a necessidade de estudos padronizados sobre as aplicações e interações dessas nanoestruturas com os sistemas biológicos.

  12. Bonos de carbono: financiarización del medioambiente en México

    Directory of Open Access Journals (Sweden)

    Vania López-Toache

    2016-01-01

    Full Text Available El trabajo tiene como objetivo analizar las medidas de mitigación para la emisión de gases efecto invernadero ( GEI al medioambiente –bonos de carbono– establecidos en el Protocolo de Kyoto. Estos parten del estudio del Teorema de Coase, el cual plantea que el mercado asignará de manera adecuada los derechos de propiedad de las externalidades provocadas por los distintos agentes económicos. Por los resultados se puede afirmar que los bonos de carbono son una forma de financiarización del medioambiente, lo cual está creando en la práctica derechos de contaminación, lo que permite que los países industrializados y empresas contaminantes reduzcan sus emisiones de GEI en países subdesarrollados como México a través de proyectos de energía renovables donde les resulta más económico y rentable.

  13. “Wrapping” X3DOM around Web Audio API

    Directory of Open Access Journals (Sweden)

    Andreas Stamoulias

    2015-12-01

    Full Text Available Spatial sound has a conceptual role in the Web3D environments, due to highly realism scenes that can provide. Lately the efforts are concentrated on the extension of the X3D/ X3DOM through spatial sound attributes. This paper presents a novel method for the introduction of spatial sound components in the X3DOM framework, based on X3D specification and Web Audio API. The proposed method incorporates the introduction of enhanced sound nodes for X3DOM which are derived by the implementation of the X3D standard components, enriched with accessional features of Web Audio API. Moreover, several examples-scenarios developed for the evaluation of our approach. The implemented examples established the achievability of new registered nodes in X3DOM, for spatial sound characteristics in Web3D virtual worlds.

  14. The Auroral Planetary Imaging and Spectroscopy (APIS) service

    CERN Document Server

    Lamy, Laurent; Henry, Florence; Sidaner, Pierre Le

    2015-01-01

    The Auroral Planetary Imaging and Spectroscopy (APIS) service, accessible online, provides an open and interactive access to processed auroral observations of the outer planets and their satellites. Such observations are of interest for a wide community at the interface between planetology and magnetospheric and heliospheric physics. APIS consists of (i) a high level database, built from planetary auroral observations acquired by the Hubble Space Telescope (HST) since 1997 with its mostly used Far-UltraViolet spectro-imagers, (ii) a dedicated search interface aimed at browsing efficiently this database through relevant conditional search criteria and (iii) the ability to interactively work with the data online through plotting tools developed by the Virtual Observatory (VO) community, such as Aladin and Specview. This service is VO compliant and can therefore also been queried by external search tools of the VO community. The diversity of available data and the capability to sort them out by relevant physical...

  15. Draft genome sequence of the Algerian bee Apis mellifera intermissa.

    Science.gov (United States)

    Haddad, Nizar Jamal; Loucif-Ayad, Wahida; Adjlane, Noureddine; Saini, Deepti; Manchiganti, Rushiraj; Krishnamurthy, Venkatesh; AlShagoor, Banan; Batainh, Ahmed Mahmud; Mugasimangalam, Raja

    2015-06-01

    Apis mellifera intermissa is the native honeybee subspecies of Algeria. A. m. intermissa occurs in Tunisia, Algeria and Morocco, between the Atlas and the Mediterranean and Atlantic coasts. This bee is very important due to its high ability to adapt to great variations in climatic conditions and due to its preferable cleaning behavior. Here we report the draft genome sequence of this honey bee, its Whole Genome Shotgun project has been deposited at DDBJ/EMBL/GenBank under the accession JSUV00000000. The 240-Mb genome is being annotated and analyzed. Comparison with the genome of other Apis mellifera sub-species promises to yield insights into the evolution of adaptations to high temperature and resistance to Varroa parasite infestation.

  16. Metadata and API Based Environment Aware Content Delivery Architecture

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    One of the limitations of current content delivery networks is lack of support for environment aware content delivery. This paper first discusses the requirements of such support, and proposes a new metadata gateway based environment aware content delivery architecture. The paper discusses in some details key functions and technologies of environment aware content delivery architecture, including its APIs and control policies. Finally the paper presents an application to illustrate advantages of environment aware content delivery architecture in the context of next generation network.

  17. Apis florea en Jordanie : origine de la population fondatrice

    OpenAIRE

    HADDAD, Nizar; FUCHS, Stefan; Randall Hepburn, H.; Radloff, Sarah E.

    2009-01-01

    International audience; A recent isolated population of Apis florea has been reported from Aqaba in Jordan at the Red Sea, consisting of numerous colonies within a still limited range which apparently is expanding. This region is about 1500 km apart from its next occurrences in Sudan where it had been introduced and first detected in 1985 and about 2000 km apart from its next natural occurrences in Iran and Oman. These bees apparently have been imported by human transport, most likely by ship...

  18. ADS 2.0: New Architecture, API and Services

    Science.gov (United States)

    Chyla, R.; Accomazzi, A.; Holachek, A.; Grant, C. S.; Elliott, J.; Henneken, E. A.; Thompson, D. M.; Kurtz, M. J.; Murray, S. S.; Sudilovsky, V.

    2015-09-01

    The ADS platform is undergoing the biggest rewrite of its 20-year history. While several components have been added to its architecture over the past couple of years, this talk will concentrate on the underpinnings of ADS's search layer and its API. To illustrate the design of the components in the new system, we will show how the new ADS user interface is built exclusively on top of the API using RESTful web services. Taking one step further, we will discuss how we plan to expose the treasure trove of information hosted by ADS (10 million records and fulltext for much of the Astronomy and Physics refereed literature) to partners interested in using this API. This will provide you (and your intelligent applications) with access to ADS's underlying data to enable the extraction of new knowledge and the ingestion of these results back into the ADS. Using this framework, researchers could run controlled experiments with content extraction, machine learning, natural language processing, etc. In this talk, we will discuss what is already implemented, what will be available soon, and where we are going next.

  19. Carbonic anhydrase from Apis mellifera: purification and inhibition by pesticides.

    Science.gov (United States)

    Soydan, Ercan; Güler, Ahmet; Bıyık, Selim; Şentürk, Murat; Supuran, Claudiu T; Ekinci, Deniz

    2017-12-01

    Carbonic anhydrase (CA) enzymes have been shown to play an important role in ion transport and in pH regulation in several organisms. Despite this information and the wealth of knowledge regarding the significance of CA enzymes, few studies have been reported about bee CA enzymes and the hazardous effects of chemicals. Using Apis mellifera as a model, this study aimed to determine the risk of pesticides on Apis mellifera Carbonic anhydrase enzyme (Am CA). CA was initially purified from Apis mellifera spermatheca for the first time in the literature. The enzyme was purified with an overall purification of ∼35-fold with a molecular weight of ∼32 kDa. The enzyme was then exposed to pesticides, including tebuconazole, propoxur, carbaryl, carbofuran, simazine and atrazine. The six pesticides dose-dependently inhibited in vitro AmCA activity at low micromolar concentrations. IC50 values for the pesticides were 0.0030, 0.0321, 0.0031, 0.0087, 0.0273 and 0.0165 μM, respectively. The AmCA inhibition mechanism of these compounds is unknown at this moment.

  20. Variation morphogeometrics of Africanized honey bees (Apis mellifera in Brazil

    Directory of Open Access Journals (Sweden)

    Lorena A. Nunes

    2012-09-01

    Full Text Available The morphometrics of the honey bee Apis mellifera L., 1758 has been widely studied mainly because this species has great ecological importance, high adaptation capacity, wide distribution and capacity to effectively adapt to different regions. The current study aimed to investigate the morphometric variations of wings and pollen baskets of honey bees Apis mellifera scutellata Lepeletier, 1836 from the five regions in Brazil. We used geometric morphometrics to identify the existence of patterns of variations of shape and size in Africanized honey bees in Brazil 16 years after the classic study with this species, allowing a temporal and spatial comparative analysis using new technological resources to assess morphometrical data. Samples were collected in 14 locations in Brazil, covering the five geographical regions of the country. The shape analysis and multivariate analyses of the wing allowed to observe that there is a geographical pattern among the population of Apis mellifera in Brazil. The geographical variations may be attributed to the large territorial extension of the country in addition to the differences between the bioregions.

  1. Improving the API dissolution rate during pharmaceutical hot-melt extrusion I: Effect of the API particle size, and the co-rotating, twin-screw extruder screw configuration on the API dissolution rate.

    Science.gov (United States)

    Li, Meng; Gogos, Costas G; Ioannidis, Nicolas

    2015-01-15

    The dissolution rate of the active pharmaceutical ingredients in pharmaceutical hot-melt extrusion is the most critical elementary step during the extrusion of amorphous solid solutions - total dissolution has to be achieved within the short residence time in the extruder. Dissolution and dissolution rates are affected by process, material and equipment variables. In this work, we examine the effect of one of the material variables and one of the equipment variables, namely, the API particle size and extruder screw configuration on the API dissolution rate, in a co-rotating, twin-screw extruder. By rapidly removing the extruder screws from the barrel after achieving a steady state, we collected samples along the length of the extruder screws that were characterized by polarized optical microscopy (POM) and differential scanning calorimetry (DSC) to determine the amount of undissolved API. Analyses of samples indicate that reduction of particle size of the API and appropriate selection of screw design can markedly improve the dissolution rate of the API during extrusion. In addition, angle of repose measurements and light microscopy images show that the reduction of particle size of the API can improve the flowability of the physical mixture feed and the adhesiveness between its components, respectively, through dry coating of the polymer particles by the API particles.

  2. The end of polling: why and how to transform a REST API into a Data Streaming API?

    CERN Document Server

    CERN. Geneva

    2017-01-01

    We know interactivity is the key to keep our user’s interest alive but we can’t reduce animation to UI anymore. Twitter, Waze, Slack… users are used to have real-time data in applications they love. But how can you turn your static API into a stream of data? By pulling? Pushing? Webhook-ing? When talking about data streaming, we often think about WebSockets. But have you ever heard of Server-Sent Events? In this tools-in-action we will compare those technologies to understand which one you should opt for depending on your usecase, and I’ll show you how we have been reducing the amount of data to transfer even further with JSON-Patch. And because real-time data is not only needed by web (and because it’s much more fun), I’ll show you how we can make a drone dance on streamed APIs.

  3. Total organic and residual carbon contents of oxissol under diferents crop systems / Efeitos dos sistemas de manejo sobre o carbono orgânico total e carbono residual de um latossolo vermelho eutroférrico

    Directory of Open Access Journals (Sweden)

    Maria de Fátima Guimarães

    2009-07-01

    Full Text Available The soil degradation is related to inadequate use of tillage systems, which result in decrease of organic matter content, chemical fertility and physical attributes. The no-tillage system is effective in protection of the soil surface. This study aimed to evaluate the carbon content of the oxissol under conventional tillage, no-tillage and pasture systems, using a secondary forest in regeneration as reference. As smaller the mobilization and larger the maintenance in soil of the vegetable residue, larger were the content of organic carbon and of residual carbon.A degradação dos solos é atribuída à utilização de sistemas de manejo inadequados, do qual resulta a diminuição da matéria orgânica, da fertilidade química e de atributos físicos. O plantio direto é eficaz na proteção da superfície do solo devido à deposição dos resíduos culturais. Este trabalho teve por objetivo avaliar o carbono orgânico total e residual de um Latossolo Vermelho eutroférrico sob os sistemas de manejo convencional, plantio direto e pasto, utilizando uma mata secundária em processo de regeneração como referência. Quanto menor a mobilização e maior a manutenção dos resíduos vegetais sobre o solo, maiores foram os teores de carbono orgânico total e de carbono residual.

  4. A SNP based high-density linkage map of Apis cerana reveals a high recombination rate similar to Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Yuan Yuan Shi

    Full Text Available BACKGROUND: The Eastern honey bee, Apis cerana Fabricius, is distributed in southern and eastern Asia, from India and China to Korea and Japan and southeast to the Moluccas. This species is also widely kept for honey production besides Apis mellifera. Apis cerana is also a model organism for studying social behavior, caste determination, mating biology, sexual selection, and host-parasite interactions. Few resources are available for molecular research in this species, and a linkage map was never constructed. A linkage map is a prerequisite for quantitative trait loci mapping and for analyzing genome structure. We used the Chinese honey bee, Apis cerana cerana to construct the first linkage map in the Eastern honey bee. RESULTS: F2 workers (N = 103 were genotyped for 126,990 single nucleotide polymorphisms (SNPs. After filtering low quality and those not passing the Mendel test, we obtained 3,000 SNPs, 1,535 of these were informative and used to construct a linkage map. The preliminary map contains 19 linkage groups, we then mapped the 19 linkage groups to 16 chromosomes by comparing the markers to the genome of A. mellfiera. The final map contains 16 linkage groups with a total of 1,535 markers. The total genetic distance is 3,942.7 centimorgans (cM with the largest linkage group (180 loci measuring 574.5 cM. Average marker interval for all markers across the 16 linkage groups is 2.6 cM. CONCLUSION: We constructed a high density linkage map for A. c. cerana with 1,535 markers. Because the map is based on SNP markers, it will enable easier and faster genotyping assays than randomly amplified polymorphic DNA or microsatellite based maps used in A. mellifera.

  5. Aggressiveness index of Apis Mellifera (Hymenoptera: Aapidae) Índice de agresividad en Apis mellifera ( Hymenoptera: Aapidae )

    OpenAIRE

    Sierra Omar Danilo; Insuasty Torres Jennyfer

    2004-01-01

    An index measuring the aggressiveness among ten colonies of Apis mellifera was elaborated based on the third generation synthetic indices by Charum et al. (1999). The index values are subject to a fixed parameter used as the beginning or standard value, and correspond to the aggressive features of some Africans colonies studied by Rothenbuler et al. (1968). In the ten colonies the index values are notably smaller than those of African colonies and are biased to the lowest values. This indicat...

  6. Obtención de fibras y gránulos de carbono para la inmovilización de enzimas

    OpenAIRE

    Martha L. Malagón M.; Yolanda Rico R.; Helda A. De López; Luis Alfonso Caicedo M.

    2011-01-01

    Se prepararon fibras y gránulos de carbono a partir de brea de carbón. Previa filtración, estabilización a 330°C y atmósfera de nitrógeno. Las fibras se obtuvieron por extrusión y los gránulos por inyección sobre agua. La inmovilización de lactasa por adsorción mostró que los gránulos de carbono fueron el soporte más adecuado, teniendo como criterios la menor caída de presión y la mayor capacidad de inmovilización. Los gránulos de carbono fueron caracterizados obteniéndose una densidad de par...

  7. Induction bending of API 5L X80 pipes; Curvamento a quente de tubos API 5L X80

    Energy Technology Data Exchange (ETDEWEB)

    Batista, Gilmar Z. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)]. E-mail: g.zacca@petrobras.com.br; Naschpitz, Leonardo [Primus Processamento de Tubos S.A. - PROTUBO, Campo Grande, RJ (Brazil)]. E-mail: naschpitz@protubo.com.br

    2005-07-01

    The present work is a part of an extensive program to make possible the application of API 5L X80 in pipeline construction in Brazil. At this stage, the effect of the induction bending process on the microstructure and mechanical properties of the pipe is presented. For this study an API 5L X80 pipe, made by the UOE process, is used. The pipe was manufactured from a plate produced by thermo-mechanically controlled rolling without accelerated cooling. The pipe bending was carried out applying a local induction heating following by water quenching. The bend section, outer and inner curvature regions, of the pipe bend were evaluated and compared with the original pipe. The longitudinal weld and transition zones were not evaluated at this stage. Dimensional analyses, microstructural evaluation, Charpy-V impact tests, and tensile tests were performed. A significant microstructural change was verified in the bend area. The yield strength of the pipe bend was found to be lower than original pipe and standard requirements. Other tensile properties and impact properties are compatible with API 5L X80 requirements. (author)

  8. Is the Sample Good Enough? Comparing Data from Twitter's Streaming API with Twitter's Firehose

    OpenAIRE

    Morstatter, Fred; Pfeffer, Jürgen; Liu, Huan; Carley, Kathleen M.

    2013-01-01

    Twitter is a social media giant famous for the exchange of short, 140-character messages called "tweets". In the scientific community, the microblogging site is known for openness in sharing its data. It provides a glance into its millions of users and billions of tweets through a "Streaming API" which provides a sample of all tweets matching some parameters preset by the API user. The API service has been used by many researchers, companies, and governmental institutions that want to extract...

  9. Use of the API 20E system to identify veterinary Enterobacteriaceae.

    OpenAIRE

    Swanson, E C; Collins, M T

    1980-01-01

    A total of 503 veterinary enteric bacterial pathogens obtained from state veterinary diagnostic laboratories were tested on API 20E strips to determine whether this rapid microidentification system could be utilized for veterinary clinical microbiology. The API 20E strip accurately identified 96% of the veterinary isolates and misidentified 3%. Identifications by the API system and the diagnostic laboratories were in agreement in 85% of the isolates, disagreement on 16% of the isolates, and 1...

  10. Contribuição dos créditos de carbono na viabilidade econômica dos contratos de fomento florestal no sul da Bahia

    Directory of Open Access Journals (Sweden)

    Erlon Barbosa Valdetaro

    2011-12-01

    Full Text Available A região do extremo sul da Bahia é caracterizada por sua extensa produção de eucalipto. Grandes empresas do setor de celulose e papel desempenham importante função na economia da região através dos programas de fomento florestal. Além disso, tem-se que alguns produtores fomentados por essas empresas possuem interesse em incrementar o retorno financeiro de seus contratos de fomento florestal através do recebimento de crédito de carbono. Nesse contexto, este trabalho teve como objetivo avaliar a contribuição dos créditos de carbono na viabilidade econômica nos contratos de fomento florestal da região. O Valor Presente Líquido (VPL, a Taxa Interna de Retorno (TIR e o Valor Anual Equivalente (VAE foram os indicadores utilizados na avaliação financeira, a uma taxa de desconto de 10% ao ano, em 45 contratos de fomento distribuídos em 11 municípios da região, e estimou-se o potencial de estocagem de carbono utilizando dados de estoque de carbono do momento em que os contratos atingiram a idade técnica de corte. Os produtores florestais informaram dados referentes à produção, produtividade e rentabilidade do plantio de eucalipto em seus contratos de fomento. Os resultados da pesquisa mostram que a comercialização dos créditos de carbono pode aumentar consideravelmente a viabilidade financeira do contrato de fomento. Dessa forma, pode-se concluir que o comércio de créditos de carbono é uma atividade viável na região e aumentará os ganhos dos produtores fomentados.

  11. Tóxicos detectados en muertes relacionadas con fuegos e intoxicaciones por monóxido de carbono

    Directory of Open Access Journals (Sweden)

    J. Gómez

    2003-01-01

    Full Text Available Se presentan en este trabajo las conclusiones del estudio realizado sobre los resultados de los análisis efectuados en muestras de sangre de 882 personas que resultaron fallecidas o intoxicadas en fuegos o a consecuencia de la inhalación de monóxido de carbono y/o de otros gases de combustión. En ellas se investigó la presencia de monóxido de carbono, cianuro y otros tóxicos tales como el alcohol etílico y los psicofármacos. Se realizan dos subgrupos, el de muertes producidas por intoxicación por monóxido de carbono y el de las ocurridas en fuegos. Se puede observar que las concentraciones de carboxihemoglobina alcanzadas en uno y otro grupo difieren sensiblemente, siendo muy superiores las encontradas en el primer grupo, con frecuencias máximas entre 50% y 70% de carboxihemoglobina frente a las detectadas en el segundo grupo cuyas frecuencias máximas se hallan entre 1% y 15%. En las muertes ocurridas en fuegos se detecta además cianuro en concentraciones variables ( 0,2 - 12 µg / ml e independientes del nivel de carboxihemoglobina detectado en cada caso. Entre los otros tóxicos más frecuentes se detectan el alcohol etílico, las benzodiacepinas, el butano y los antidepresivos, entre otros. El alcohol etílico se detecta en diferentes concentraciones observándose una mayor concentración en los casos de fuegos, lo que indica que puede tener influencia en la ocurrencia de accidentes relacionados con ellos

  12. Gestión Ambiental empresarial: cálculo de la huella de carbono en la industria vitivinícola.

    OpenAIRE

    Rosa Ana Rodriguez; Adriana Belfort Martinez; Stella Maris Udaquiola

    2014-01-01

    La huella de carbono es un indicador ambiental que busca cuantificar la cantidad de emisiones de gases de efecto invernadero (GHG). Su medición se convierte en una herramienta que permite trabajar bajo el concepto de eco-eficiencia e identificar oportunidades de reducción de consumo energético, ya que este último es la principal fuente de emisión de GHG a nivel mundial. El presente trabajo aplica la metodología PAS 2050:2011 para la medición de la huella de carbono, en la producción del vino ...

  13. Comportamiento de vigas de hormigón reforzadas a cortante con tejidos de fibras de carbono pegados con resina epoxi

    OpenAIRE

    2010-01-01

    En este trabajo se muestran los resultados experimentales obtenidos sobre vigas de hormigón reforzadas a cortante con tejidos de fibra de carbono pegados exteriormente con resinas epoxi. Durante el desarrollo del trabajo se han analizado los desplazamientos de las vigas reforzadas con CFRP (polímeros reforzados con fibras de carbono) y se ha realizado una comparación del comportamiento mecánico de los sistemas de refuerzo estudiados. Se han realizado cuatro vigas de hormigón de 1.200 mm ...

  14. Niveles de carbono orgánico total en el Suelo de Conservación del Distrito Federal, centro de México

    OpenAIRE

    Gilberto Vela Correa; Jorge López Blanco; María de Lourdes Rodríguez Gamiño

    2012-01-01

    El Suelo de Conservación (SC) del Distrito Federal es un reservorio de carbono, por lo que es importante contar con datos sobre su capacidad de almacenamiento bajo diferentes tipos de cobertura vegetal. En este trabajo se estimó el contenido de carbono orgánico total en suelos (COS) de áreas con cobertura de bosque, uso agrícola y en áreas reforestadas. Se delimitaron unidades geomorfogenéticas que sirvieron de base para el muestreo de suelos. En total se estudiaron 50 sitios con muestras ...

  15. OPORTUNIDADES DO MERCADO DE CRÉDITO DE CARBONO PARA USINAS SUCROALCOOLEIRAS DO BRASIL

    Directory of Open Access Journals (Sweden)

    RODRIGUES, Elaine Miranda

    2009-04-01

    Full Text Available Because of production and competitiveness in industry and technology, the global climate is in constant change, involving important discussions about this issue, for example, the increaseof carbon dioxide released into the atmosphere by industrially countries. The questions have as objective to revert the situation, involving some steps and processes that demonstrate the importance of this discussion as an current model of sustainable use of nature. From these negotiations that Kyoto’s Protocol was created, generating new income resources. The general objective of this paper was to investigate, by literature, what opportunities are been created to the firms, specially of cane sugar cultivation – animportant segment to invest cause of the energy co-generation projects – with the purpose to reduce the environmental damage and increase the incomes, by the concept of Clean DevelopmentMechanism. After an important process of interviews we can conclude that there are opportunities to the firms of cane sugar process and cultivation, because of the national and international demand by clean energy use.Com o aumento da produção e competitividade no ramo industrial e tecnológico, o climado planeta vem passando por constantes transformações, envolvendo sérias discussões sobre o assunto, aexemplo disso, o aumento de gás carbônico lançado na atmosfera por países mais industrializados. Oquestionamento tem como relevância reverter à situação em que se encontra o mundo, envolvendoalgumas das etapas que demonstram a importância do assunto no modelo atual de consumo sustentável danatureza. E a partir de negociações como essas é que se deu a origem do Protocolo de Kyoto em 1997 noJapão, que estipula metas de redução das emissões de poluição para países mais desenvolvidos, ofertandoassim a possibilidade de países em desenvolvimento comercializarem emissões no Mercado de Crédito deCarbono, gerando uma nova fonte de renda. O

  16. Distribución a profundidad del carbono orgánico en los suelos de México

    Directory of Open Access Journals (Sweden)

    Fernando Paz

    2016-07-01

    Full Text Available La caracterización de la distribución vertical del carbono orgánico en los suelos (COS en México es una tarea importante, dada la evidencia acumulada que muestra que el COS puede ser desestabilizado por diferentes mecanismos al incrementar la profundidad a la que se encuentra en el perfil. Con el objetivo de modelar la variación del COS con la profundidad, se analizó una base de datos de COS de perfiles de suelos distribuidos en todo México (base de datos INEGI-COLPOS. Esta base se depuró usando diferentes restricciones congruentes con el objetivo de desarrollar modelos matemáticos de la distribución del carbono con la profundidad (z. Los resultados de los ajustes estadísticos mostraron que modelo logarítmico, COS(z=a-b ln(z, resultó adecuado para lo planteado, por lo que se procedió a su síntesis. Se usó la propiedad de que un conjunto de rectas que se intersectan en un punto común, sus parámetros generan una línea recta. Con base en ella se desarrolló un esquema para estimar el carbono orgánico inerte (COI del espacio b-a del modelo logarítmico. Adicionalmente, para realizar estimaciones del COS a profundidad (hasta su valor máximo usando sólo el valor del COS de 0 a 30 cm, se desarrolló un método para realizar estas estimaciones a partir de parámetros asociados a los ecosistemas y tipos de vegetación. Los resultados de los ejercicios realizados para estimar el COI y el carbono orgánico a profundidad en los suelo usando sólo el COS 30 cm muestran ser adecuados y pueden ser implementados en forma operativa.

  17. Efeito de leguminosas nos atributos físicos e carbono orgânico de um Luvissolo

    OpenAIRE

    Nascimento,João Tavares; Silva,Ivandro de França da; Santiago,Roberval Diniz; Silva Neto,Luiz de França da

    2005-01-01

    A degradação de um solo sob cultivo é resultante, principalmente, de seu manejo inadequado, com reflexos nas baixas produtividades das culturas. Com a finalidade de avaliar o efeito de leguminosas nos atributos físicos e carbono orgânico (CO) de um Luvissolo, realizou-se, no município de Alagoinha (PB), um experimento entre 1997 e 1999, com as seguintes espécies: crotalária (Crotalaria juncea, L), guandu (Cajanus cajan,L), guandu anão (Cajanus cajan (L) Millsp), calopogônio (Calopogonium mucu...

  18. Remoción de Contaminantes Atmosféricos Sox y Nox mediante Nanotubos de Carbono

    OpenAIRE

    Saavedra Labastida, Erika

    2013-01-01

    En el presente proyecto de investigación se realizó la evaluación de la remoción de los contaminantes atmosféricos provenientes de fuentes móviles, mediante nanotubos de carbono (NTC) comerciales. Para conocer las propiedades de los NTC empleados, fueron caracterizados fisicoquímicamente mediante diferentes análisis tales como MEB, MET, Raman, DRX y BET, los resultados que se obtuvieron mostraron óptimas propiedades fisicoquímicas las cuales permiten que sean empleados como ...

  19. Influência do nanotubo de carbono no processo de cura da resina epóxi

    OpenAIRE

    Luciana De Simone Cividanes Coppio

    2012-01-01

    Recentemente, nanotubos de carbono (CNTs), em especial os funcionalizados, têm sido adicionados em matrizes epóxi devido às suas extraordinárias propriedades mecânicas, elétricas e térmicas. Entretanto, não está claro como os nanotubos, funcionalizados ou não, influenciam o processo de cura da resina epóxi. Assim, o objetivo deste trabalho é estudar a influência de CNTs, funcionalizados ou não, no processo de cura da resina epóxi, utilizando em especial a técnica de espectroscopia de luminesc...

  20. Aportes para la estimación de la huella de carbono en los grandes asentamientos urbanos de Argentina

    OpenAIRE

    Rosana Ferraro; María Cecilia Gareis; Laura Zulaica

    2013-01-01

    El cambio climático y su efecto más inmediato, el calentamiento global, plantean desafíos para la gestión ambiental de las ciudades. Uno de ellos es estimar su huella de carbono con la finalidad de morigerar los potenciales impactos. El presente trabajo propone calcular las emisiones de CO2 producidas por las actividades antrópicas de los 15 asentamientos urbanos de Argentina de más de 300.000 habitantes. Para ello se analizaron por localidad los consumos de energía eléctrica y se calcularon ...

  1. Síntesis, Activación Química y Aplicaciones de Nanoestructuras de Carbono

    OpenAIRE

    Jiménez Cotillas, Vicente

    2012-01-01

    El presente trabajo forma parte de un amplio programa de investigación sobre la preparación de nanoestructuras de carbono y su aplicación en procesos de interés energético, industrial y medioambiental que, desde el año 2003 hasta la actualidad, se está desarrollando en el Departamento de Ingeniería Química de la Universidad de Castilla-La Mancha (UCLM). Durante las últimas décadas se ha asistido al inicio de una revolución científica basada en la capacidad de medir, manipular y organizar l...

  2. Propriedades microbiológicas e bioquímicas do ciclo do carbono em solo sob diferentes coberturas vegetais

    OpenAIRE

    Marina Yumi Horta Miyauchi

    2007-01-01

    Os distúrbios causados pela interferência humana no ambiente demandam atenção quanto a alterações nas propriedades químicas, físicas, microbiológicas e bioquímicas do solo, as quais podem ser usadas como indicadoras de sustentabilidade de um determinado ecossistema terrestre. O objetivo desse trabalho foi avaliar algumas propriedades microbiológicas e bioquímicas relacionadas ao ciclo do carbono em solo sob quatro diferentes coberturas vegetais (vegetação nativa - NAT, área reflorestada com a...

  3. Sistema de seguridad para elaborar nanopartículas de carbono a escala de laboratorio

    Directory of Open Access Journals (Sweden)

    Dania Soguero González

    2012-08-01

    Full Text Available Las nanopartículas de carbono (NPC han sido de las más utilizadas, debido a sus propiedades. Muchas de estas propiedades que hacen tan útil a las NPC también pueden hacerlas tóxicas para las células y el organismo y por lo tanto deben ser manipuladas con precaución. El Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear (CEADEN está desarrollando un programa de investigación que incluye la síntesis NPC usando el método de descarga de arco sumergida en agua. En este trabajo se describe el sistema de nanoseguridad implementado en los laboratorios del CEADEN para el desarrollo de las mejores prácticas con NPC. Dicho sistema se construyó sobre la base de un análisis de seguridad. Se usó el método ¿Qué pasa si? y un procedimiento que emplea un árbol de decisiones que permite clasificar los laboratorios en clases de acuerdo a niveles de peligrosidad. Se identificaron los peligros de importancia significativa. Para la estimación del riesgo de estas se construyó una matriz Probabilidad/Consecuencia, donde se reflejó el riesgo asociado a cada uno de los eventos analizados y se clasificó en las categorías de alto, medio y bajo riesgo. Finalmente, se procedió a implementar las medidas de protección personal, técnicas y organizativas definidas a partir del análisis de riesgo efectuado en forma de procedimientos.

  4. Microbiological corrosion in low carbon steels; Corrosion microbiologica en aceros de bajo carbono

    Energy Technology Data Exchange (ETDEWEB)

    Medina-Custodio, O; Ortiz-Prado, A; Jacobo-Armendariz, V. H; Schouwenaars-Franssens, R [Universidad Nacional Autonoma de Mexico, Mexico, D.F. (Mexico)]. E-mail: medina_1979@yahoo.com; armandoo@servidor.unam.mx; vjacobo@dgapa.unam.mx; raf_schouweenaars@yahoo.com

    2009-01-15

    The Microbiologically Induced Corrosion affects several industries, such as oil industry where it is estimated that 20% to 30% pipes failures are related with microorganism. The chemical reactions generate ions transfer, this validate the use of electrochemical technique for its analysis. Coupons submerged in a nutritional medium with presence and absence of three different microorganisms during two periods, 48 hours and 28 days were studied. Polarization resistance (Rp) and Electrochemical Impedance Spectroscopy (EIS) techniques were applied to determine the corrosively of the systems. The results show a greater corrosive effect of abiotic systems, this indicates a microorganisms protection effect to the metal, opposite to the first hypothesis. This result was ratified observing surface coupons by using Scanning Electron Microscopy (SEM) technique. A possible mechanism based on Evans - Tafel graph is proposed to explain inhibitor microorganism effect. [Spanish] La corrosion microbiologica es un tipo comun de deterioro que afecta diversas industrias, una de ellas es la petrolera en la que se estiman que el 20% o 30% de fallas en las tuberias de trasporte de hidrocarburos es favorecida por microorganismos. Las reacciones quimicas que sustentan estos, generan transferencia de iones, lo que justifica el empleo de tecnicas electroquimicas para su analisis. En este trabajo, se estudiaron probetas de acero de bajo carbono SAE 1018, sumergidas en un medio nutritivo rico en cloruros en presencia y ausencia de tres diferentes cargas microbianas, en tiempos de exposicion de 48 horas y 28 dias. Se realizaron ensayos de resistencia a la polarizacion (Rp) y espectroscopia de impedancia electroquimica (EIS) para determinar el efecto corrosivo de los diferentes sistemas. Los resultados muestran que el medio abiotico causa el mayor efecto corrosivo, lo que indica un efecto protector de los microorganismos al metal contradiciendo la hipotesis inicialmente propuesta. La observacion

  5. CAMBIOS EN LAS RESERVAS DE CARBONO ORGÁNICO DEL SUELO BAJO DIFERENTES COBERTURAS

    Directory of Open Access Journals (Sweden)

    José I. Bojórquez Serrano

    2015-01-01

    Full Text Available Las reservas de carbono orgánico en los suelos (COS y sus cambios en el tiempo son un tema ambiental de actualidad, asimismo las pérdidas de COS que ocurren con la conversión de ecosistemas naturales a agrosistemas, contribuyen con emisiones a la atmósfera, al calentamiento global y el cambio climático. El objetivo de este trabajo fue estudiar los cambios en las reservas de COS bajo diferentes coberturas de la cuenca del río Mololoa, Nayarit, México. El análisis de los cambios se realiza por diferencia en las reservas de COS en los primeros 20 cm de 13 perfiles de suelos con diferentes coberturas, dos en bosques de encino, dos en bosques de pino, uno en pastizal, uno en cultivo de aguacate y siete en terrenos cultivados con caña de azúcar. Las coberturas estables de bosque y pastizal generan ganancias en las reservas de COS; siendo el pastizal el que registra la mayor cantidad (2,65 Mg ha -1 año -1 , seguido por el bosque de encino (0,40-0,47 Mg ha -1 año -1 , el bosque de pino (0,15-0,38 Mg ha -1 año -1 y la arboleda de aguacate (0,29 Mg ha -1 año -1 . Mientras que la cobertura de cultivo de caña de azúcar generó pérdidas en las reservas de COS, entre 0,12-0,84 Mg ha -1 año -1

  6. Solar Eclipse Computer API: Planning Ahead for August 2017

    Science.gov (United States)

    Bartlett, Jennifer L.; Chizek Frouard, Malynda; Lesniak, Michael V.; Bell, Steve

    2016-01-01

    With the total solar eclipse of 2017 August 21 over the continental United States approaching, the U.S. Naval Observatory (USNO) on-line Solar Eclipse Computer can now be accessed via an application programming interface (API). This flexible interface returns local circumstances for any solar eclipse in JavaScript Object Notation (JSON) that can be incorporated into third-party Web sites or applications. For a given year, it can also return a list of solar eclipses that can be used to build a more specific request for local circumstances. Over the course of a particular eclipse as viewed from a specific site, several events may be visible: the beginning and ending of the eclipse (first and fourth contacts), the beginning and ending of totality (second and third contacts), the moment of maximum eclipse, sunrise, or sunset. For each of these events, the USNO Solar Eclipse Computer reports the time, Sun's altitude and azimuth, and the event's position and vertex angles. The computer also reports the duration of the total phase, the duration of the eclipse, the magnitude of the eclipse, and the percent of the Sun obscured for a particular eclipse site. On-line documentation for using the API-enabled Solar Eclipse Computer, including sample calls, is available (http://aa.usno.navy.mil/data/docs/api.php). The same Web page also describes how to reach the Complete Sun and Moon Data for One Day, Phases of the Moon, Day and Night Across the Earth, and Apparent Disk of a Solar System Object services using API calls.For those who prefer using a traditional data input form, local circumstances can still be requested that way at http://aa.usno.navy.mil/data/docs/SolarEclipses.php. In addition, the 2017 August 21 Solar Eclipse Resource page (http://aa.usno.navy.mil/data/docs/Eclipse2017.php) consolidates all of the USNO resources for this event, including a Google Map view of the eclipse track designed by Her Majesty's Nautical Almanac Office (HMNAO). Looking further ahead, a

  7. Influencia del carbono y el cromo en el comportamiento tribológico de aleaciones férreas

    Directory of Open Access Journals (Sweden)

    García, A.

    2005-12-01

    Full Text Available This study compares the abrasive wear resistance of a carbon steel, used in the linings of coal mills, and ferrous alloys with different chromium and carbon content. It also analyses the influence of chromium and carbon content on mechanical properties, such as hardness, and microstructure. The abrasive wear resistance of the different materials was determined by means of ASTM G 105, "Standard Test Method for Conducting Wet Sand/Rubber Wheel Abrasion Test". A blasting test was used to study erosive wear resistance.

    En este estudio se analiza la influencia, en las propiedades tribológicas, del contenido en carbono para distintas aleaciones férreas con similares contenidos en cromo, así como la influencia del cromo cuando el contenido en carbono es semejante. También, se analizó la influencia de estos elementos en propiedades como la dureza y en la microestructura de las aleaciones. Para el estudio tribológico se llevaron a cabo dos ensayos, el ensayo descrito en la norma ASTM G105: Standard Test Method for Conducting Wet Sand/Rubber Wheel Abrasion Test y ensayos de chorreo.

  8. DESCRIPCIÓN DE LA DINÁMICA DE CARBONO EN SUELOS FORESTALES MEDIANTE UN MODELO DE RESERVORIOS

    Directory of Open Access Journals (Sweden)

    Gustavo Orellana-Rivadeneyra

    2012-01-01

    Full Text Available Se propone una aproximación sobre variables medioambientales mediante funciones de distribución dependientes del tiempo para simplificar un modelo de la dinámica del carbono orgánico en el suelo. El modelo se basa en el concepto de reservorios, que supone que los diferentes estados de la materia orgánica del suelo constituyen masas homogéneas. Este modelo se enfoca en el intercambio de materia orgánica entre dichas masas, estableciendo relaciones de contacto. Usando el modelo simplificado se calculó la acumulación de materia orgánica en el suelo y la emisión de CO2 desde un ecosistema de bosque de pino (Pinus elliottii ubicado en Gainesville, Florida, EU. Se verificó la viabilidad de las aproximaciones en el modelo para estudiar la dinámica del carbono orgánico en suelos forestales. Se calculó la acumulación relativa de materia orgánica en el suelo. Con esto se obtuvo una estimación de la actividad del bosque de P. elliottii como secuestrador.

  9. Análisis de soldabilidad de aceros inoxidables con aceros de medio y bajo carbono por SMAW

    Directory of Open Access Journals (Sweden)

    José Luddey Marulanda Arevalo

    2013-12-01

    Full Text Available Se presenta un estudio de la soldabilidad de aceros inoxidables austeníticos AISI 304 y AISI 316 con aceros de bajo y medio carbono AISI 1020 – AISI 1045, empleando como materiales de aporte los electrodos EutecTrode® 52 NG, 54 NG y 57 NG, mediante el proceso de arco eléctrico con electrodo revestido (SMAW. Para analizar la soldabilidad de estos electrodos cuando se realiza la unión de aceros inoxidables con aceros al carbono, se practicaron pruebas metalográficas y ensayos mecánicos de dureza, doblez y tracción, con el fin de observar el comportamiento tanto de la zona afectada térmicamente como del cordón de soldadura, a partir del cambio en las propiedades mecánicas y metalúrgicas en las diferentes regiones de las uniones soldadas. Durante el proceso de soldadura se siguió una especificación del procedimiento de soldadura (WPS, para que los resultados fueran repetibles, minimizando los problemas de agrietamiento en caliente, agrietamiento en frío, formación de fase sigma y precipitación de carburos.

  10. Flujo de Carbono Orgánico Total (COT en una cuenca andina: caso subcuenca Río Las Piedras

    Directory of Open Access Journals (Sweden)

    María Cristina Ordóñez Díaz

    2014-06-01

    Full Text Available El estudio se realizó para calcular el flujo de carbono transportado por la cuenca del río Las Piedras, típica representativa de los Andes tropicales suramericanos, reservorio estratégico del recurso hídrico. Se desarrolló una investigación observacional durante 20 meses sobre el recurso hídrico, mediante un diseño completamente aleatorio, estratificado por altura (msnm, analizando el contenido de COT, las propiedades físico-químicas del agua y variables hidrometeorológicas (caudal y variación estacional. La concentración promedio de COT aportada principalmente desde la zona alta fue 9 mgL-1. Se transporta en promedio un flujo de 2003,5 Kg.dia-1 de COT, asociado al caudal y la estacionalidad húmeda. El análisis en relación con variables físico-químicas permite concluir que el río disuelve CO2 en sus aguas. Este estudio contribuye al análisis del comportamiento de los ríos andinos y su aporte al ciclo global del carbono.

  11. Macelignan inhibits bee pathogenic fungi Ascophaera apis growth through HOG1 pathway

    Directory of Open Access Journals (Sweden)

    Y.K. Shin

    2016-01-01

    Full Text Available Ascosphaera apis is a bee pathogen that causes bee larvae infection disease, to which treatment is not yet well investigated. The aim of this study was to investigate antifungal susceptibility in vitro against A. apis and to identify a new antifungal agent for this pathogen through minimal inhibitory concentration (MIC assay and western blot analysis. Macelignan had 1.56 and 3.125 μg/mL MIC against A. apis after 24 and 48 h, respectively, exhibiting the strongest growth inhibition against A. apis among the tested compounds (corosolic acid, dehydrocostus lactone, loganic acid, tracheloside, fangchinoline and emodin-8-O-β-D-glucopyranoside. Furthermore, macelignan showed a narrow-ranged spectrum against various fungal strains without any mammalian cell cytotoxicity. In spite of miconazole having powerful broad-ranged anti-fungal activity including A. apis, it demonstrated strong cytotoxicity. Therefore, even if macelignan alone was effective as an antifungal agent to treat A. apis, combined treatment with miconazole was more useful to overcome toxicity, drug resistance occurrence and cost effectiveness. Finally, HOG1 was revealed as a target molecule of macelignan in the anti-A. apis activity by inhibiting phosphorylation using S. cerevisiae as a model system. Based on our results, macelignan, a food-grade antimicrobial compound, would be an effective antifungal agent against A. apis infection in bees.

  12. Improvements and extensions to API 618 related to pulsation and mechanical response studies

    NARCIS (Netherlands)

    Eijk, A.; Smeulers, J.P.M.; Blodgett, L.E.; Smalley, A.J.

    1999-01-01

    Purchasers of reciprocating compressors need a standard to help ensure reliable installations. The PNEUROP standard evolved in Europe, and the API 618 Standard in the U.S.A. Frequent application and generally good experience, worldwide, have led to four releases of API 618, the last dated June 1995.

  13. Influence of humidity on the phase behavior of API/polymer formulations.

    Science.gov (United States)

    Prudic, Anke; Ji, Yuanhui; Luebbert, Christian; Sadowski, Gabriele

    2015-08-01

    Amorphous formulations of APIs in polymers tend to absorb water from the atmosphere. This absorption of water can induce API recrystallization, leading to reduced long-term stability during storage. In this work, the phase behavior of different formulations was investigated as a function of relative humidity. Indomethacin and naproxen were chosen as model APIs and poly(vinyl pyrrolidone) (PVP) and poly(vinyl pyrrolidone-co-vinyl acetate) (PVPVA64) as excipients. The formulations were prepared by spray drying. The water sorption in pure polymers and in formulations was measured at 25°C and at different values of relative humidity (RH=25%, 50% and 75%). Most water was absorbed in PVP-containing systems, and water sorption was decreasing with increasing API content. These trends could also be predicted in good agreement with the experimental data using the thermodynamic model PC-SAFT. Furthermore, the effect of absorbed water on API solubility in the polymer and on the glass-transition temperature of the formulations was predicted with PC-SAFT and the Gordon-Taylor equation, respectively. The absorbed water was found to significantly decrease the API solubility in the polymer as well as the glass-transition temperature of the formulation. Based on a quantitative modeling of the API/polymer phase diagrams as a function of relative humidity, appropriate API/polymer compositions can now be selected to ensure long-term stable amorphous formulations at given storage conditions.

  14. Alótropos del carbono: experimentos de laboratorio que se hacen famosos años después

    Directory of Open Access Journals (Sweden)

    F. Rodríguez Reinoso

    2011-03-01

    Full Text Available Es destacable que el “descubrimiento” de los tres últimos alótropos del elemento carbono se haya producido en un intervalo de pocos años: fullerenos en 1985, nanotubos en 1991 y grafeno en 2004.

  15. APIS - a novel approach for conditioning honey bees

    Directory of Open Access Journals (Sweden)

    Nicholas Hagen Kirkerud

    2013-04-01

    Full Text Available Honey bees perform robustly in different conditioning paradigms. This makes them excellent candidates for studying mechanisms of learning and memory at both an individual and a population level. Here we introduce a novel method of honey bee conditioning: APIS, the Automatic Performance Index System. In an enclosed walking arena where the interior is covered with an electric grid, presentation of odours from either end can be combined with weak electric shocks to form aversive associations. To quantify behavioural responses, we continuously monitor the movement of the bee by an automatic tracking system. We found that escapes from one side to the other, changes in velocity as well as distance and time spent away from the punished odour are suitable parameters to describe the bee’s learning capabilities.Our data show that in a short-term memory test the response rate for the conditioned stimulus in APIS correlates well with response rate obtained from conventional Proboscis Extension Response (PER-conditioning. Additionally, we discovered that bees modulate their behaviour to aversively learned odours by reducing their rate, speed and magnitude of escapes and that both generalisation and extinction seem to be different between appetitive and aversive stimuli. The advantages of this automatic system make it ideal for assessing learning rates in a standardised and convenient way, and its flexibility adds to our toolbox for studying honey bee behaviour.

  16. From where did the Western honeybee (Apis mellifera) originate?

    Science.gov (United States)

    Han, Fan; Wallberg, Andreas; Webster, Matthew T

    2012-08-01

    The native range of the honeybee Apis mellifera encompasses Europe, Africa, and the Middle East, whereas the nine other species of Apis are found exclusively in Asia. It is therefore commonly assumed that A. mellifera arose in Asia and expanded into Europe and Africa. However, other hypotheses for the origin of A. mellifera have also been proposed based on phylogenetic trees constructed from genetic markers. In particular, an analysis based on >1000 single-nucleotide polymorphism markers placed the root of the tree of A. mellifera subspecies among samples from Africa, suggestive of an out-of-Africa expansion. Here, we re-evaluate the evidence for this and other hypotheses by testing the robustness of the tree topology to different tree-building methods and by removing specimens with a potentially hybrid background. These analyses do not unequivocally place the root of the tree of A. mellifera subspecies within Africa, and are potentially consistent with a variety of hypotheses for honeybee evolution, including an expansion out of Asia. Our analyses also support high divergence between western and eastern European populations of A. mellifera, suggesting they are likely derived from two distinct colonization routes, although the sources of these expansions are still unclear.

  17. Genetic variation in natural honeybee populations, Apis mellifera capensis

    Science.gov (United States)

    Hepburn, Randall; Neumann, Peter; Radloff, Sarah E.

    2004-09-01

    Genetic variation in honeybee, Apis mellifera, populations can be considerably influenced by breeding and commercial introductions, especially in areas with abundant beekeeping. However, in southern Africa apiculture is based on the capture of wild swarms, and queen rearing is virtually absent. Moreover, the introduction of European subspecies constantly failed in the Cape region. We therefore hypothesize a low human impact on genetic variation in populations of Cape honeybees, Apis mellifera capensis. A novel solution to studying genetic variation in honeybee populations based on thelytokous worker reproduction is applied to test this hypothesis. Environmental effects on metrical morphological characters of the phenotype are separated to obtain a genetic residual component. The genetic residuals are then re-calculated as coefficients of genetic variation. Characters measured included hair length on the abdomen, width and length of wax plate, and three wing angles. The data show for the first time that genetic variation in Cape honeybee populations is independent of beekeeping density and probably reflects naturally occurring processes such as gene flow due to topographic and climatic variation on a microscale.

  18. Parasitic Cape honeybee workers, Apis mellifera capensis, evade policing

    Science.gov (United States)

    Martin, Stephen J.; Beekman, Madeleine; Wossler, Theresa C.; Ratnieks, Francis L. W.

    2002-01-01

    Relocation of the Cape honeybee, Apis mellifera capensis, by bee-keepers from southern to northern South Africa in 1990 has caused widespread death of managed African honeybee, A. m. scutellata, colonies. Apis mellifera capensis worker bees are able to lay diploid, female eggs without mating by means of automictic thelytoky (meiosis followed by fusion of two meiotic products to restore egg diploidy), whereas workers of other honeybee subspecies are able to lay only haploid, male eggs. The A. m. capensis workers, which are parasitizing and killing A. m. scutellata colonies in northern South Africa, are the asexual offspring of a single, original worker in which the small amount of genetic variation observed is due to crossing over during meiosis (P. Kryger, personal communication). Here we elucidate two principal mechanisms underlying this parasitism. Parasitic A. m. capensis workers activate their ovaries in host colonies that have a queen present (queenright colonies), and they lay eggs that evade being killed by other workers (worker policing)-the normal fate of worker-laid eggs in colonies with a queen. This unique parasitism by workers is an instance in which a society is unable to control the selfish actions of its members.

  19. Polymorphism analysis of csd gene in six Apis mellifera subspecies.

    Science.gov (United States)

    Wang, Zilong; Liu, Zhiyong; Wu, Xiaobo; Yan, Weiyu; Zeng, Zhijiang

    2012-03-01

    The complementary sex determination (csd) gene is the primary gene determining the gender of honey bees (Apis spp). In this study we analyzed the polymorphism of csd gene in six Apis mellifera subspecies. The genomic region 3 of csd gene in these six A. mellifera was cloned, and identified. A total of 79 haplotypes were obtained from these six subspecies. Analysis showed that region 3 of csd gene has a high level of polymorphism in all the six A. mellifera subspecies. The A. m. anatolica subspecies has a slightly higher nucleotide diversity (π) than other subspecies, while the π values showed no significant difference among the other five subspecies. The phylogenetic tree showed that all the csd haplotypes from different A. mellifera subspecies are scattered throughout the tree, without forming six different clades. Population differentiation analysis showed that there are significant genetic differentiations among some of the subspecies. The NJ phylogenetic tree showed that the A. m. caucasica and A. m. carnica have the closest relationship, followed by A. m. ssp, A. m. ligustica, A. m. carpatica and A. m. anatolica that were gathered in the tree in turn.

  20. 往复压缩机标准API-618、API-11P的异同点及其应用浅谈%The Similarities and Differences of Reciprocating Compressor Standards of API-618 and API-11P and Discussion of Its Application

    Institute of Scientific and Technical Information of China (English)

    李明悦; 扈滨

    2011-01-01

    PI Standard 618 and API Specification 11P are the standards for reciprocating compressors by American Petroleum Institute ( API) .This paper has speeified the applications of the two standards in the compressors which used in the Cas Treatment Plant of SES natural gas pmject.And the similarities and differences between them are compared.%API Standard 618和API Specification 11P都是美国石油学会(API)针对往复压缩机制定的标准.结合中海石油SES天然气项目中的气体处理厂压缩机单元对这两个标准的应用,对两者之间的异同点进行比较.

  1. Towards Standardized Patient Data Exchange: Integrating a FHIR Based API for the Open Medical Record System.

    Science.gov (United States)

    Kasthurirathne, Suranga N; Mamlin, Burke; Grieve, Grahame; Biondich, Paul

    2015-01-01

    Interoperability is essential to address limitations caused by the ad hoc implementation of clinical information systems and the distributed nature of modern medical care. The HL7 V2 and V3 standards have played a significant role in ensuring interoperability for healthcare. FHIR is a next generation standard created to address fundamental limitations in HL7 V2 and V3. FHIR is particularly relevant to OpenMRS, an Open Source Medical Record System widely used across emerging economies. FHIR has the potential to allow OpenMRS to move away from a bespoke, application specific API to a standards based API. We describe efforts to design and implement a FHIR based API for the OpenMRS platform. Lessons learned from this effort were used to define long term plans to transition from the legacy OpenMRS API to a FHIR based API that greatly reduces the learning curve for developers and helps enhance adhernce to standards.

  2. Evaluación del secuestro de carbono con diferentes alternativas de gestión selvícola en monte bajo de castaño en el Norte de España

    OpenAIRE

    Prada Monteagudo, Marta

    2014-01-01

    Las masas forestales y las actividades de manejo forestal juegan un papel importante en la fijación del carbono. Los objetivos del estudio fueron determinar la línea base de almacenamiento de carbono en monte bajo de castaño (Castanea sativa Mill.), evaluar el efecto de la gestión forestal y validar los resultados del modelo. El área de estudio se localiza en el norte de España. El modelo CO2FIX se utilizó para estimar el contenido de carbono en la biomasa, suelo y productos, evaluándose 5 al...

  3. The Ruby UCSC API: accessing the UCSC genome database using Ruby

    Directory of Open Access Journals (Sweden)

    Mishima Hiroyuki

    2012-09-01

    Full Text Available Abstract Background The University of California, Santa Cruz (UCSC genome database is among the most used sources of genomic annotation in human and other organisms. The database offers an excellent web-based graphical user interface (the UCSC genome browser and several means for programmatic queries. A simple application programming interface (API in a scripting language aimed at the biologist was however not yet available. Here, we present the Ruby UCSC API, a library to access the UCSC genome database using Ruby. Results The API is designed as a BioRuby plug-in and built on the ActiveRecord 3 framework for the object-relational mapping, making writing SQL statements unnecessary. The current version of the API supports databases of all organisms in the UCSC genome database including human, mammals, vertebrates, deuterostomes, insects, nematodes, and yeast. The API uses the bin index—if available—when querying for genomic intervals. The API also supports genomic sequence queries using locally downloaded *.2bit files that are not stored in the official MySQL database. The API is implemented in pure Ruby and is therefore available in different environments and with different Ruby interpreters (including JRuby. Conclusions Assisted by the straightforward object-oriented design of Ruby and ActiveRecord, the Ruby UCSC API will facilitate biologists to query the UCSC genome database programmatically. The API is available through the RubyGem system. Source code and documentation are available at https://github.com/misshie/bioruby-ucsc-api/ under the Ruby license. Feedback and help is provided via the website at http://rubyucscapi.userecho.com/.

  4. Valoración económica del almacenamiento de agua y carbono en la comunidad campesina Villa de Junín

    Directory of Open Access Journals (Sweden)

    Miguel Vila Balbin

    2015-12-01

    Full Text Available El objetivo ha sido estimar el valor económico que generan los bofedales en el almacenamiento de agua y carbono en la comunidad campesina Villa de Junín en el departamento de Junín, Perú. El proceso de recolección de datos a estado enfocado en datos meteorológicos (temperatura y precipitación, datos de la actividad económica predominante (ganadería, recolección de muestras de suelo para hallar el contenido de carbono y capacidad volumétrica; posteriormente se hizo la comparación del beneficio percibido por la actividad ganadera y el beneficio que se podría obtener por los servicios que brinda un bofedal (almacenamiento de agua y carbono. Entre los resultados respecto a la precipitación anual se ha determinado 22 367 664 m3/año, del cual un 42,56 % (9 294 933,67 m3/ año regresa a la atmósfera a través del proceso de la evapotranspiración, quedando una oferta hídrica disponible de 13 072 730,33 m3/año, que representa un 57,44 % de la oferta hídrica total; la productividad hídrica es de 0,01 S/./m3. El costo de oportunidad que tiene la ganadería es de 200,38 S/./ha /año; el valor económico de agua y carbono es de S/. 48 974 181,79 y S/. 44 305 010,31 respectivamente. Se concluye que el almacenamiento de agua y carbono brindan mayores ingresos económicos a la población que la actividad ganadera.

  5. UTILIZAÇÃO DE LODO ANAERÓBIO COMO FONTE EXTERNA DE CARBONO NO PROCESSO DE DESNITRIFICAÇÃO DE ÁGUAS RESIDUÁRIAS

    Directory of Open Access Journals (Sweden)

    José Tavares de Sousa

    1999-04-01

    Full Text Available RESUMO O processo de desnitrificação reduz, de forma geral, nitrato a nitrogênio molecular; essa redução acontece associada ao ganho de elétrons. Na desnitrificação, as bactérias heterotróficas utilizam carbono orgânico como fonte doadora de elétrons. No caso de esgotos sanitários já tratados (tratamento secundário e como estes não dispõem de carbono orgânico suficiente exigem, portanto, uma fonte externa de carbono orgânico. Assim sendo, o objetivo desta pesquisa foi avaliar o potencial de desnitrificação de uma coluna preenchida com lodo anaeróbio sem o uso de outra fonte externa de carbono; esta coluna foi carregada pelo topo superior com lodo e, por meio de bomba peristáltica, o afluente nitrificado alimentava a coluna em fluxo ascendente. Durante 30 semanas de operação, a eficiência de remoção na coluna de desnitrificação permaneceu em torno de 72%, o lodo anaróbio se comportou como fonte externa de carbono adequada para o processo e a maior eficiência de remoção de nitrato ocorreu quando a coluna foi operada com maior concentração de sólidos suspenso voláteis (SSV; portanto, a eficiência de remoção de nitrato é função da concentração de SSV e, consequentemente, da masssa de lodo na coluna.

  6. Asynchronous API Pattern and its Application%异步接口模式及其应用

    Institute of Scientific and Technical Information of China (English)

    何华海; 丁柯

    2002-01-01

    In distributed systems,high efficiency can be achieved using asynchronous API between client and server.This paper provides an architectural pattern that implements asynchronous API generally. Asynchronous methods donot execute operations directly,however,they delegate the sending and receiving process to individual threads via aqueue ,the client deals with results by means of callback ,wait or check. Synchronous API is implemented on the baseof asynchronous API. Presently the asynchronous API pattern has been employed in the implementation of messagequeue middleware ISMQ.

  7. Research on API Based on Visual Programming Platforms%基于可视化平台的 API 接口研究

    Institute of Scientific and Technical Information of China (English)

    关玉蓉

    2015-01-01

    In a variety of visual programming platforms, especially with the external network environment, , a large number of API functions under Windows can help reflect strong advanced programming skills proving to be a multiplier effect. This paper firstly introduces the API function and the dynamic link library DLL, then briefly ex-plains the classification of API functions, and focuses on how to call the API function and its application of API function in the visual platform. The paper finally describes the skills and notes to pay attention for users when call-ing the API function, which enables them to master the advanced programming skills of API interface.%在各种可视化编程平台中,尤其是与外部网络环境相结合,为了体现强大的高级编程能力,可用Windows系统提供的大量API函数,必然会起到事半功倍的效果。本文首先介绍了API函数以及动态链接库DLL,其次简要说明了API函数的分类,然后重点分析了在可视化平台中如何调用API函数及其应用API函数的高级编程能力,最后阐述了用户调用API函数的技巧和注意事项,以提高用户灵活掌握API接口的高级编程应用能力。

  8. API5 confers cancer stem cell-like properties through the FGF2-NANOG axis

    Science.gov (United States)

    Song, K-H; Cho, H; Kim, S; Lee, H-J; Oh, S J; Woo, S R; Hong, S-O; Jang, H S; Noh, K H; Choi, C H; Chung, J-Y; Hewitt, S M; Kim, J-H; Son, M; Kim, S-H; Lee, B I; Park, H-C; Bae, Y-K; Kim, T W

    2017-01-01

    Immune selection drives the evolution of tumor cells toward an immune-resistant and cancer stem cell (CSC)-like phenotype. We reported that apoptosis inhibitor-5 (API5) acts as an immune escape factor, which has a significant role in controlling immune resistance to antigen-specific T cells, but its functional association with CSC-like properties remains largely unknown. In this study, we demonstrated for the first time that API5 confers CSC-like properties, including NANOG expression, the frequency of CD44-positive cells and sphere-forming capacity. Critically, these CSC-like properties mediated by API5 are dependent on FGFR1 signaling, which is triggered by E2F1-dependent FGF2 expression. Furthermore, we uncovered the FGF2-NANOG molecular axis as a downstream component of API5 signaling that is conserved in cervical cancer patients. Finally, we found that the blockade of FGFR signaling is an effective strategy to control API5high human cancer. Thus, our findings reveal a crucial role of API5 in linking immune resistance and CSC-like properties, and provide the rationale for its therapeutic application for the treatment of API5+ refractory tumors. PMID:28092370

  9. Apoptosis inhibitor 5 (API-5; AAC-11; FIF) is upregulated in human carcinomas in vivo.

    Science.gov (United States)

    Koci, Lenka; Chlebova, Katarina; Hyzdalova, Martina; Hofmanova, Jirina; Jira, Miroslav; Kysela, Petr; Kozubik, Alois; Kala, Zdenek; Krejci, Pavel

    2012-04-01

    Apoptosis inhibitor 5 (API-5) is a 55 kDa nuclear protein with potent anti-apoptotic signaling in tumor cells in vitro. In this study, we analyzed the expression of the API-5 protein in vivo in a broad spectrum of human carcinomas, including those of the colon, lung, liver, kidney, pancreas, stomach and esophagus using tumor tissues obtained during tumor resection. The results showed significant upregulation of API-5 expression in biopsies of lung (23%, n=13) and colorectal tumors (33%, n=27) in comparison with biopsies from the adjacent normal tissue. Colon cancer biopsies were used to study the cell populations with an upregulated level of expression of API-5 more closely. Using a magnetic bead-based selection for the epithelial cell marker EpCAM, we purified epithelial cells from the tumor and control tissues and analyzed these cells for API-5 expression by western immunoblotting. We observed that EpCAM-positive tumor cells expressed API-5 in all three colorectal cancer cases tested, in contrast to the control EpCAM-positive and EpCAM-negative cells isolated from the control or tumor tissues. These data suggest that the expression of the API-5 protein is upregulated in tumor epithelial cells and may serve as a prognostic marker in colorectal cancer.

  10. api, A novel Medicago truncatula symbiotic mutant impaired in nodule primordium invasion.

    Science.gov (United States)

    Teillet, Alice; Garcia, Joseph; de Billy, Françoise; Gherardi, Michèle; Huguet, Thierry; Barker, David G; de Carvalho-Niebel, Fernanda; Journet, Etienne-Pascal

    2008-05-01

    Genetic approaches have proved to be extremely useful in dissecting the complex nitrogen-fixing Rhizobium-legume endosymbiotic association. Here we describe a novel Medicago truncatula mutant called api, whose primary phenotype is the blockage of rhizobial infection just prior to nodule primordium invasion, leading to the formation of large infection pockets within the cortex of noninvaded root outgrowths. The mutant api originally was identified as a double symbiotic mutant associated with a new allele (nip-3) of the NIP/LATD gene, following the screening of an ethylmethane sulphonate-mutagenized population. Detailed characterization of the segregating single api mutant showed that rhizobial infection is also defective at the earlier stage of infection thread (IT) initiation in root hairs, as well as later during IT growth in the small percentage of nodules which overcome the primordium invasion block. Neither modulating ethylene biosynthesis (with L-alpha-(2-aminoethoxyvinylglycine or 1-aminocyclopropane-1-carboxylic acid) nor reducing ethylene sensitivity in a skl genetic background alters the basic api phenotype, suggesting that API function is not closely linked to ethylene metabolism or signaling. Genetic mapping places the API gene on the upper arm of the M. truncatula linkage group 4, and epistasis analyses show that API functions downstream of BIT1/ERN1 and LIN and upstream of NIP/LATD and the DNF genes.

  11. Investigation into process-induced de-aggregation of cohesive micronised API particles.

    Science.gov (United States)

    Hoffmann, Magnus; Wray, Patrick S; Gamble, John F; Tobyn, Mike

    2015-09-30

    The aim of this study was to assess the impact of unit processes on the de-aggregation of a cohesive micronised API within a pharmaceutical formulation using near-infrared chemical imaging. The impact on the primary API particles was also investigated using an image-based particle characterization system with integrated Raman analysis. The blended material was shown to contain large, API rich domains which were distributed in-homogeneously across the sample, suggesting that the blending process was not aggressive enough to disperse aggregates of micronised drug particles. Cone milling, routinely used to improve the homogeneity of such cohesive formulations, was observed to substantially reduce the number and size of API rich domains; however, several smaller API domains survived the milling process. Conveyance of the cone milled formulation through the Alexanderwerk WP120 powder feed system completely dispersed all remaining aggregates. Importantly, powder feed transmission of the un-milled formulation was observed to produce an equally homogeneous API distribution. The size of the micronised primary drug particles remained unchanged during powder feed transmission. These findings provide further evidence that this powder feed system does induce shear, and is in fact better able to disperse aggregates of a cohesive micronised API within a blend than the blend-mill-blend step.

  12. EDGE REMOVAL OF 3D POLYGONAL MODEL USING MAYA API

    Directory of Open Access Journals (Sweden)

    SAMEER ARORA

    2010-09-01

    Full Text Available In various applications of computer graphics, 3D polygonal modeling is used, which consists millions of triangular polygon. In this polygon attributes – vertices, edges and faces’ details are to be stored. In order to control the processing time, storing space, and transfer speed, it is often required to reduce the information ofthese polygonal 3D models. In this paper an effort is made to reduce the number of edges. There are various methods to reduce faces and edges of these 3D models. A C++ dynamic link library as Maya Plugin has been created to remove number of edges of 3D triangular polygon model using the Quadric Error Metrics (QEM in MAYA v2010 x64 API. QEM allows fast and accurate geometric simplification of 3D models.

  13. AES Encryption and Decryption Using Direct3D 10 API

    Directory of Open Access Journals (Sweden)

    Adrian Marius Chiuta

    2011-06-01

    Full Text Available Current video cards (GPUs – Graphics Processing Units are very programmable, have become much more powerful than the CPUs and they are very affordable. In this paper, we present an implementation for the AES algorithm using Direct3D 10 certified GPUs. The graphics API Direct3D 10 is the first version that allows the use of integer operations, making from the traditional GPUs (that works only with floating point numbers, General Purpose GPUs that can be used for a large number of algorithms, including encryption. We present the performance of the symmetric key encryption algorithm – AES, on a middle range GPU and on a middle range quad core CPU. On the testing system, the developed solution is almost 3 times faster on the GPU than on one single core CPU, showing that the GPU can perform as an efficient cryptographic accelerator.

  14. Fragilización por Hidrógeno de los Aceros API 5L X60 y API 5L X80 Hydrogen Embrittlement of API 5L X60 and API 5L X80 Steels

    OpenAIRE

    Bruno A Araújo; Jorge A Palma; Vilar, Eudésio O.; Silva, Antonio A.

    2011-01-01

    Se ha determinado el comportamiento mecánico de los aceros API 5L grados X60 y X80, fragilizados por hidrógeno ambiental y por hidrógeno interno. El potencial y la densidad de corriente para la generación del hidrógeno fueron determinados por polarización potenciodinámica, y el tiempo de saturación estimado a partir de datos de difusividad y solubilidad obtenidos en ensayos de permeación con una célula electroquímica. La carga de hidrógeno para reproducir las condiciones de la fragilización p...

  15. API, Cloud computing, WebGIS and cartography

    Directory of Open Access Journals (Sweden)

    Andrea Favretto

    2013-05-01

    Full Text Available This paper explores some of the digital mapping processes available on the Internet in order to analyse their cartographic congruence. It will focus on WebGIS-based cartography in relation to what is produced using Mash-up site maps. These websites often use Googlebased maps in order to produce their own cartography. Thus, we can identify two main typologies of Internet mapping sites, which are characterized by the ownership or non-ownership of their cartographic bases. This paper will critically assess the cartography employed in the two different instances. A concise introduction to the Cloud Computing Internet propagated phenomenon is also premised in order to provide the reader with an accurate frame of reference. Cloud Computing has encouraged a significant Internet participation via the Application Programming Interface software (API, leading to mash-up cartographic websites.

  16. Pheromonal contest between honeybee workers ( Apis mellifera capensis)

    Science.gov (United States)

    Moritz, R. F. A.; Simon, U. E.; Crewe, R. M.

    2000-10-01

    Queenless workers of the Cape honeybee ( Apis mellifera capensis) can develop into reproductives termed pseudoqueens. Although they morphologically remain workers they become physiologically queenlike, produce offspring, and secrete mandibular gland pheromones similar to those of true queens. However, after queen loss only very few workers gain pseudoqueen status. A strong intracolonial selection governs which workers start oviposition and which remain sterile. The "queen substance", 9-keto-2(E)-decenoic acid (9-ODA), the dominant compound of the queen's mandibular gland pheromones, suppresses the secretion of queenlike mandibular gland pheromones in workers. It may act as an important signal in pseudoqueen selection. By analysing the mandibular gland pheromones of workers kept in pairs, we found that A. m. capensis workers compete to produce the strongest queen-like signal.

  17. A non-policing honey bee colony (Apis mellifera capensis)

    Science.gov (United States)

    Beekman, Madeleine; Good, Gregory; Allsopp, Mike; Radloff, Sarah; Pirk, Chris; Ratnieks, Francis

    2002-09-01

    In the Cape honey bee Apis mellifera capensis, workers lay female eggs without mating by thelytokous parthenogenesis. As a result, workers are as related to worker-laid eggs as they are to queen-laid eggs and therefore worker policing is expected to be lower, or even absent. This was tested by transferring worker- and queen-laid eggs into three queenright A. m. capensis discriminator colonies and monitoring their removal. Our results show that worker policing is variable in A. m. capensis and that in one colony worker-laid eggs were not removed. This is the first report of a non-policing queenright honey bee colony. DNA microsatellite and morphometric analysis suggests that the racial composition of the three discriminator colonies was different. The variation in policing rates could be explained by differences in degrees of hybridisation between A. m. capensis and A. m. scutellata, although a larger survey is needed to confirm this.

  18. ATRIBUTOS FÍSICO-HÍDRICOS E ESTOQUE DE CARBONO EM NEOSSOLO QUARTZARÊNICO SOB PLANTIO DE Eucalyptus urograndis

    Directory of Open Access Journals (Sweden)

    Allan Libanio Pelissari

    2013-11-01

    Full Text Available O objetivo  do  trabalho foi avaliar o efeito da colheita do eucalipto  nos atributos físico-hídricos e no estoque de carbono em Neossolo Quartzarênico. O estudo foi conduzido em um povoamento  de  Eucalyptus urograndis  com sete anos de idade, em Dom Aquino, MT, Brasil.  As avaliações  foram realizadas em dois períodos do ano (chuvoso e seco, e coletadas amostras de solo nas profundidades de 0–0,2; 0,2–0,4; 0,4–0,6; 0,6–0,8 e 0,8–1,0 m, antes e após a colheita semimecanizada, para a determinação da porosidade total, densidade, condutividade hidráulica saturada, conteúdo de água e estoque de carbono no solo, enquanto a resistência à penetração foi determinada até  0,8 m. O sistema semimecanizado de colheita alterou significativamente a resistência do solo à penetração e a porosidade total no período chuvoso do ano. A densidade do solo  foi inferior nas camadas superficiais, ao passo que a condutividade hidráulica saturada reduziu após a colheita. O conteúdo de água no solo foi o atributo que regulou  o impacto da colheita semimecanizada sobre o solo.  O estoque de carbono aumentou  após a colheita no período chuvoso.Palavra-chave compactação do solo, carbono orgânico, colheita de madeira.PHYSICAL-HYDRIC ATTRIBUTES AND CARBON STOCK IN TYPIC QUARTZIPISAMMENT UNDER Eucalyptus urograndis STANDS ABSTRACTThe aim of this study was to evaluate the effect of eucalyptus harvesting in the physical-hydric attributes and carbon storage in Typic Quartzipisamment. The study was conducted with seven years old Eucalyptus urograndis stand, in Dom Aquino, MT, Brazil. The evaluations were conducted in two seasons (wet and dry, with soil sampling at depths of 0-0.2, 0.2-0.4, 0.4-0.6, 0.6-0.8 and 0.8-1.0 m, before and after the semi-mechanized harvesting, for the total porosity determination, bulk density, hydraulic conductivity, water content and soil carbon stock, while the soil penetration resistance was

  19. Síntesis y caracterización de materiales híbridos basados en nanotubos de carbono

    OpenAIRE

    García Gutiérrez, Ángel Pablo

    2013-01-01

    Los nanotubos de carbono están despertando un gran interés investigativo en los últimos años debido a sus excepcionales propiedades electrónicas, mecánicas, térmicas, químicas y por sus potenciales aplicaciones en nanociencia y nanotecnología. Por otro lado, el óxido de zinc también genera un gran interés tanto científico como tecnológico debido a sus extraordinarias propiedades ópticas y eléctricas. Se trata de un material semiconductor con demostradas propiedades fotocatalíticas, que le con...

  20. Aportes para la estimación de la huella de carbono en los grandes asentamientos urbanos de Argentina

    Directory of Open Access Journals (Sweden)

    Rosana Ferraro

    2013-01-01

    Full Text Available El cambio climático y su efecto más inmediato, el calentamiento global, plantean desafíos para la gestión ambiental de las ciudades. Uno de ellos es estimar su huella de carbono con la finalidad de morigerar los potenciales impactos. El presente trabajo propone calcular las emisiones de CO2 producidas por las actividades antrópicas de los 15 asentamientos urbanos de Argentina de más de 300.000 habitantes. Para ello se analizaron por localidad los consumos de energía eléctrica y se calcularon las emisiones de CO2 por sector de demanda eléctrica. Los resultados muestran que Argentina, en general, y los grandes asentamientos, en particular, tienen una baja contribución de emisiones de CO2, que se asocian en orden decreciente con la actividad industrial, residencial y comercial.

  1. Aportes para la estimación de la huella de carbono en los grandes asentamientos urbanos de Argentina

    Directory of Open Access Journals (Sweden)

    Rosana Ferraro

    2013-07-01

    Full Text Available El cambio climático y su efecto más inmediato, el calentamiento global, plantean desafíos para la gestión ambiental de las ciudades. Uno de ellos es estimar su huella de carbono con la finalidad de morigerar los potenciales impactos. El presente trabajo propone calcular las emisiones de CO2 producidas por las actividades antrópicas de los 15 asentamientos urbanos de Argentina de más de 300.000 habitantes. Para ello se analizaron por localidad los consumos de energía eléctrica y se calcularon las emisiones de CO2 por sector de demanda eléctrica. Los resultados muestran que Argentina, en general, y los grandes asentamientos, en particular, tienen una baja contribución de emisiones de CO2, que se asocian en orden decreciente con la actividad industrial, residencial y comercial.

  2. Projeto e análise de uma roda em fibra de carbono de um jato regional.

    OpenAIRE

    Rodrigo Borin

    2008-01-01

    Esta dissertação apresenta o projeto preliminar e a análise estrutural por elementos finitos de uma roda em fibra de carbono com perfil aerodinâmico de uma aeronave da categoria jato regional, juntamente com seus componentes, como rolamentos e chavetas de transmissão de força de frenagem. Será descrito o perfil aerodinâmico das hélices, assim como a geometria da roda e os materiais selecionados. Considerações térmicas e aerodinâmicas a respeito da roda também serão levadas em conta, assim com...

  3. Dinámica del carbono en los ecosistemas de páramo de los Andes neotropicales: revisión de literatura sobre modelos y parámetros relevantes

    NARCIS (Netherlands)

    Sevink, J.; Tonneijck, F.H.; Kalbitz, K.; Cammeraat, L.H.; Cuesta, F.; Sevink, J.; Llambí, L.D.; De Bièvre, B.; Posner, J.

    2014-01-01

    Resumen Los suelos del páramo almacenan cantidades excepcionales de carbono debido a las condiciones edáficas y climáticas sobre las cuales se desarrollan. Este gran reservorio de carbono está amenazado debido a los efectos del cambio climático y las dinámicas de uso de la tierra. No obstante, el de

  4. Genetic structure of Apis mellifera macedonica in the Balkan Peninsula based on microsatellite DNA polymorphism

    DEFF Research Database (Denmark)

    Uzunov, Aleksandar; Meixner, Marina D; Kiprijanovska, Hrisula;

    2014-01-01

    The genetic variability of honey bees (Apis mellifera L.) from south eastern Europe was investigated using microsatellite analyses of 107 samples from Albania, the Republic of Macedonia, Greece and Bulgaria together with 42 reference samples (Apis mellifera carnica) from Slovenia. Genetic structure...... and spatial analyses of the microsatellite data showed a clear distinction between the Slovenian bees and all other populations, and confirmed the existence of Apis mellifera macedonica as an indigenous honey bee population in the regions that were sampled. In most areas however, varying degrees...

  5. Clarification of some api characteristics in relation to caribou (Rangifer tarandus

    Directory of Open Access Journals (Sweden)

    William O. Pruitt, Jr.

    1990-09-01

    Full Text Available A total of 2177 comparisons of api hardness vs. density in northern Saskatchewan, southeastern Manitoba and northeastern Finland revealed no consistent correlation (r varied from +.70 to -.17. A total of 1395 comparisons of horizontal hardness of the top layer of api to vertical hardness of the same layer of api in southeastern Manitoba, northeastern Finland and far eastern middle Finland revealed no consistent correlation (r varied from +.99 to -.20. Therefore one cannot substitute density for hardness nor horizontal hardness of the top layer for vertical hardness of the top layer in the terms of the Värriö Snow Index.

  6. Estimación de carbono almacenado en bosques de oyamel y ciprés en Texcoco, Estado de México

    Directory of Open Access Journals (Sweden)

    Yunuen Bolaños González

    2017-01-01

    Full Text Available Las emisiones de carbono (C a la atmósfera, así como sus reservorios, en el sector de agricultura, silvicultura y otros usos del suelo son significativas en el balance global del ciclo del carbono; sin embargo, a pesar de esta importancia, es el sector con la mayor incertidumbre en el balance global debido principalmente a la falta de conocimiento preciso de los factores de emisión, por lo que se requiere mayor investigación en el tema. Debido a lo anterior, este trabajo tuvo como objetivo estimar el C almacenado en los cinco depósitos considerados en ecosistemas forestales: biomasa viva sobre el suelo, biomasa viva debajo del suelo, madera muerta sobre el suelo, mantillo y carbono orgánico del suelo (COS en dos sitios de muestreo ubicados en las faldas del Monte Tláloc, Texcoco, Estado de México: el primero en un bosque de oyamel (Abies religiosa y el segundo en un bosque de ciprés (Cupressus lusitanica. El promedio de la densidad de carbono en el bosque de oyamel en los cinco depósitos estimados fue de 376 Mg ha‑1, siendo el depósito más importante el de biomasa aérea (59%, seguido del COS (22%; en tanto que en el bosque de ciprés fue de 205 Mg ha-1, siendo el depósito con mayor densidad el COS (50%, seguido de biomasa aérea (36%. Los valores de densidad de carbono para biomasa aérea en el caso de bosque de oyamel fueron superiores a los reportados en otros trabajos; lo cual se explica por la existencia de árboles de grandes dimensiones de esta especie en el sitio de muestreo, lo cual nos da una idea precisa del potencial como almacén de carbono que este tipo de vegetación tiene cuando llegan a estados maduros.

  7. The Arabidopsis apyrase AtAPY1 is localized in the Golgi instead of the extracellular space

    Directory of Open Access Journals (Sweden)

    Schiller Madlen

    2012-07-01

    Full Text Available Abstract Background The two highly similar Arabidopsis apyrases AtAPY1 and AtAPY2 were previously shown to be involved in plant growth and development, evidently by regulating extracellular ATP signals. The subcellular localization of AtAPY1 was investigated to corroborate an extracellular function. Results Transgenic Arabidopsis lines expressing AtAPY1 fused to the SNAP-(O6-alkylguanine-DNA alkyltransferase-tag were used for indirect immunofluorescence and AtAPY1 was detected in punctate structures within the cell. The same signal pattern was found in seedlings stably overexpressing AtAPY1-GFP by indirect immunofluorescence and live imaging. In order to identify the nature of the AtAPY1-positive structures, AtAPY1-GFP expressing seedlings were treated with the endocytic marker stain FM4-64 (N-(3-triethylammoniumpropyl-4-(p-diethylaminophenyl-hexatrienyl-pyridinium dibromide and crossed with a transgenic line expressing the trans-Golgi marker Rab E1d. Neither FM4-64 nor Rab E1d co-localized with AtAPY1. However, live imaging of transgenic Arabidopsis lines expressing AtAPY1-GFP and either the fluorescent protein-tagged Golgi marker Membrin 12, Syntaxin of plants 32 or Golgi transport 1 protein homolog showed co-localization. The Golgi localization was confirmed by immunogold labeling of AtAPY1-GFP. There was no indication of extracellular AtAPY1 by indirect immunofluorescence using antibodies against SNAP and GFP, live imaging of AtAPY1-GFP and immunogold labeling of AtAPY1-GFP. Activity assays with AtAPY1-GFP revealed GDP, UDP and IDP as substrates, but neither ATP nor ADP. To determine if AtAPY1 is a soluble or membrane protein, microsomal membranes were isolated and treated with various solubilizing agents. Only SDS and urea (not alkaline or high salt conditions were able to release the AtAPY1 protein from microsomal membranes. Conclusions AtAPY1 is an integral Golgi protein with the substrate specificity typical for Golgi apyrases. It is

  8. IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom allergen Api m 10 evaluated by protein array technology.

    Science.gov (United States)

    Van Vaerenbergh, Matthias; De Smet, Lina; Rafei-Shamsabadi, David; Blank, Simon; Spillner, Edzard; Ebo, Didier G; Devreese, Bart; Jakob, Thilo; de Graaf, Dirk C

    2015-02-01

    Api m 10 has recently been established as novel major allergen that is recognized by more than 60% of honeybee venom (HBV) allergic patients. Previous studies suggest Api m 10 protein heterogeneity which may have implications for diagnosis and immunotherapy of HBV allergy. In the present study, RT-PCR revealed the expression of at least nine additional Api m 10 transcript isoforms by the venom glands. Two distinct mechanisms are responsible for the generation of these isoforms: while the previously known variant 2 is produced by an alternative splicing event, novel identified isoforms are intragenic chimeric transcripts. To the best of our knowledge, this is the first report of the identification of chimeric transcripts generated by the honeybee. By a retrospective proteomic analysis we found evidence for the presence of several of these isoforms in the venom proteome. Additionally, we analyzed IgE reactivity to different isoforms by protein array technology using sera from HBV allergic patients, which revealed that IgE recognition of Api m 10 is both isoform- and patient-specific. While it was previously demonstrated that the majority of HBV allergic patients display IgE reactivity to variant 2, our study also shows that some patients lacking IgE antibodies for variant 2 display IgE reactivity to two of the novel identified Api m 10 variants, i.e. variants 3 and 4.

  9. Histochemical Comparison of the Hypopharyngeal Gland in Apis cerana Fabricius, 1793 Workers and Apis mellifera Linnaeus, 1758 Workers

    Directory of Open Access Journals (Sweden)

    Guntima Suwannapong

    2010-01-01

    Full Text Available Hypopharyngeal glands of honeybee are age-dependent structures that change with the size of acini and are correlated with various social behaviors. The histochemical structure of Apis cerana and A. mellifera worker hypopharyngeal glands in four different developmental stages wes stained with ninhydrin Schiff's and periodic acid Schiff's reagents (PAS for localization of proteins and carbohydrates, respectively, and examined with light microscopy. Nurse bees of both honeybee species had significantly larger glands as compared to guards and forgers, but there were no statistically significant differences between these two species after accounting for caste. Gland protein concentration increased progressively in nurse bees, and this was correlated with the appearance of enriched protein granules in the cytoplasm. In addition, the hypopharyngeal gland protein concentration of A. mellifera was higher than that of A. cerana even though gland size was not significantly different between species. However, gland size was shown to have decreased progressively in foragers and guards.

  10. Homology differences between complete Sacbrood virus genomes from infected Apis mellifera and Apis cerana honeybees in Korea.

    Science.gov (United States)

    Reddy, Kondreddy Eswar; Yoo, Mi Sun; Kim, Young-Ha; Kim, Nam-Hee; Ramya, Mummadireddy; Jung, Ha-Na; Thao, Le Thi Bich; Lee, Hee-Soo; Kang, Seung-Won

    2016-04-01

    Sacbrood virus (SBV) represents a serious threat to the health of managed honeybees. We determined four complete SBV genomic sequences (AmSBV-Kor1, AmSBV-Kor2, AcSBV-Kor3, and AcSBV-Kor4) isolated from Apis mellifera and Apis cerana in various regions of South Korea. A phylogenetic tree was constructed from the complete genomic sequences of these Korean SBVs (KSBVs) and 21 previously reported SBV sequences from other countries. Three KSBVs (not AmSBV-Kor1) clustered with previously reported Korean genomes, but separately from SBV genomes from other countries. The KSBVs shared 90-98 % identity, and 89-97 % identity with the genomes from other countries. AmSBV-Kor1 was least similar (~90 % identity) to the other KSBVs, and was most similar to previously reported strains AmSBV-Kor21 (97 %) and AmSBV-UK (93 %). Phylogenetic analysis of the partial VP1 region sequences indicated that SBVs clustered by host species and country of origin. The KSBVs were aligned with nine previously reported complete SBV genomes and compared. The KSBVs were most different from the other genomes at the end of the 5' untranslated region and in the entire open reading frame. A SimPlot graph of the VP1 region confirmed its high variability, especially between the SBVs infecting A. mellifera and A. cerana. In this genomic region, SBVs from A. mellifera species contain an extra continuous 51-nucleotide sequence relative to the SBVs from A. cerana. This genomic diversity may reflect the adaptation of SBV to specific hosts, viral cross-infections, and the spatial distances separating the KSBVs from other SBVs.

  11. Telephone Interpreter Services (TIS)-Asian and Pacific Islander (API) Language Fiscal Year Quarterly Dataset

    Data.gov (United States)

    Social Security Administration — This dataset displays our quarterly national TIS call volume for over 45 API languages for the current fiscal year. A fiscal year runs from October through September...

  12. Telephone Interpreter Services (TIS)-Asian and Pacific Islander (API) Language Yearly Dataset

    Data.gov (United States)

    Social Security Administration — This dataset displays our national TIS call volume for over 45 API languages for the last three fiscal years. A fiscal year runs from October through September. We...

  13. Bilingual education, indigenous language and culture: the case of Apyãwa Tapirapé

    Directory of Open Access Journals (Sweden)

    Maria Gorete Neto

    Full Text Available Bilingual schools are recognized as an important resource to increase the chances of language survival but in many cases have proven to be ineffective. Within the Apyãwa Tapirapé Indian Tribe (central Brazil, an effective bilingual school does exist; however, this study shows that even a successful school brings complications for the community. Audio-recorded interviews, in which teachers and leaders discuss their bilingual school and its consequences for the Apyãwa Tapirapé people, reveal that they feel that the school has changed the Apyãwa Tapirapé lifestyle in both negative and positive ways. A continuous evaluation and ongoing reconstruction of educational aspects is proposed as a way to both attend to the needs and to relieve the worries of groups like the Apyãwa Tapirapé with respect to the impact of their school on the community.

  14. A review on the taste masking of bitter APIs: hot-melt extrusion (HME) evaluation.

    Science.gov (United States)

    Maniruzzaman, Mohammed; Boateng, Joshua S; Chowdhry, Babur Z; Snowden, Martin J; Douroumis, Dennis

    2014-02-01

    The majority of active pharmaceutical ingredients (APIs) found in oral dosage forms have a bitter taste. Masking the unpleasant taste of bitter, APIs is a major challenge in the development of such oral dosage forms. Taste assessment is an important quality-control parameter for evaluating taste-masked formulations of any new molecular entity. Hot-melt extrusion (HME) techniques, have very recently, been accepted from an industrial compliance viewpoint in relation to both manufacturing operations and development of pharmaceuticals. HME achieves taste masking of bitter APIs via various mechanisms such as the formation of solid dispersions and inter-molecular interactions and this has led to its wide-spread use in pharmaceutical formulation research. In this article, the uses of various taste evaluation methods and HME as continuous processing techniques for taste masking of bitter APIs used for the oral delivery of drugs are reviewed.

  15. Candida albicans response to spaceflight (NASA STS-115) --- GSM1231690_Slide_43 API

    Data.gov (United States)

    National Aeronautics and Space Administration — A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic...

  16. Dosis Letal Media (DL50 de algunos aceites esenciales y biocidas efectivos para el control de Ascosphaera apis en Apis mellifera L. - Median Lethal Dose (LD50 of some essential oils and biocides effective for the control of Ascosphaera apis on Apis mellifera L

    Directory of Open Access Journals (Sweden)

    Albo, Graciela N

    2010-10-01

    Full Text Available ResumenLa ascofaeriosis o cría yesificada, es una enfermedad de la abeja melífera (Apis mellifera L. causada por el hongo Ascosphaera apis que produce la momificación de las larvas. Los aceites esenciales poseen efectos antimicrobianos y han sido utilizados para el control de cría yesificada. Por otra parte, a nivel mundial se han probado gran cantidad de productos de síntesis, pero ninguno ha resultado 100 % eficaz. SummaryChalkbrood is a disease of the honeybee (Apis mellifera L caused by the fungus Ascosphaera apis that transforms larvae into mummies. Essential oils have showed antimicrobial activity and have been used in the control of chalkbrood. Moreover, world-wide, great number of synthesized products have been assayed but no one has resulted 100% effective.

  17. S E- GEOD-50881 Study Samples --- Candida albicans response to spaceflight (NASA STS-115) API

    Data.gov (United States)

    National Aeronautics and Space Administration — A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic...

  18. A E- GEOD-50881 Gene Chip Assay --- Candida albicans response to spaceflight (NASA STS-115) API

    Data.gov (United States)

    National Aeronautics and Space Administration — A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic...

  19. BUILDING MODEL ANALYSIS APPLICATIONS WITH THE JOINT UNIVERSAL PARAMETER IDENTIFICATION AND EVALUATION OF RELIABILITY (JUPITER) API

    Science.gov (United States)

    The open-source, public domain JUPITER (Joint Universal Parameter IdenTification and Evaluation of Reliability) API (Application Programming Interface) provides conventions and Fortran-90 modules to develop applications (computer programs) for analyzing process models. The input ...

  20. Three-dimensional model of the honeybee venom allergen Api m 7: structural and functional insights.

    Science.gov (United States)

    Georgieva, Dessislava; Greunke, Kerstin; Betzel, Christian

    2010-06-01

    Api m 7 is one of the major protease allergens of the honeybee venom. It consists of a serine protease-like (SPL) and a CUB domain. The knowledge about the structure and function of Api m 7 is limited mainly to its amino acid sequence. Three-dimensional models of the two structural domains were constructed using their amino acid sequences and the crystallographic coordinates of prophenoloxidase-activating factor (PPAF-II) as a template for the SPL domain and the coordinates of porcine spermadhesin PSP-II for the CUB domain. The structural organization of Api m 7 suggests that the CUB domain is involved in interactions with natural substrates while the SPL domain probably activates zymogens. IgE epitopes and antigenic sites were predicted. Api m 7 shows structural and functional similarity to the members of the PPAF-II family. Possible substrates, function and evolution of the enzyme are discussed in the paper.

  1. Antagonistic Effect of Gut Bacteria in the Hybrid Carniolan Honey Bee, Apis Mellifera Carnica, Against Ascosphaera Apis, the Causal Organism of Chalkbrood Disease

    Directory of Open Access Journals (Sweden)

    Omar Mohamed O. M.

    2014-06-01

    Full Text Available The objective of this study was to isolate and characterize bacterial strains associated with the gut of the hybrid Carniolan honey bee, Apis mellifera carnica, and to determine their in vitro and in vivo potential against Ascosphaera apis, the causal organism of chalkbrood disease, with the purpose of exploring feasible biological control. Six bacterial strains were isolated from healthy worker honey bees by culture-dependent methods. Six fungal strains (A3, A4, A7, A8, A9, and A15 of A. apis were isolated from larvae suffering from chalkbrood disease on Yeast-Glucose-Starch agar (YGPSA medium. All bacteria were identified by a combination of morphology, Gram stain, and 16S rRNA sequence analysis, and fungal strains were identified by morphology and 5.8S rRNA. In vitro and in vivo inhibition assays were carried out to determine the ability of bacterial isolates to inhibit A. apis, the causal agent of chalkbrood disease. The analysis of 16S rRNA sequences revealed that four bacterial strains (B2, B4, B10, and B100 belong to Bacillus subtilis species, and two strains (P1 and P5 belong to Pseudomonas fluorescence. Significant differences in antagonistic activity of all bacterial strains were observed. B. subtilis isolate B2 showed the highest antagonistic activity, as measured by the inhibition zone against A. apis, followed by the P1 strain of P. fluorescence. SEM analysis also supports the antagonistic activity of these bacteria against A. apis. This study provides a theoretical basis for biological control of honey bee chalkbrood disease.

  2. Revoke and Let Live: A Secure Key Revocation API for Cryptographic Devices

    OpenAIRE

    Cortier, Véronique; Steel,Graham; Wiedling, Cyrille

    2012-01-01

    While extensive research addresses the problem of establishing session keys through cryptographic protocols, relatively little work has appeared addressing the problem of revocation and update of long term keys. We present an API for symmetric key management on embedded devices that supports revocation and prove security properties design in the symbolic model of cryptography. Our API supports two modes of revocation: a passive mode where keys have an expiration time, and an active mode where...

  3. Sensitivity Analysis of Fatigue Crack Growth Model for API Steels in Gaseous Hydrogen

    Science.gov (United States)

    Amaro, Robert L; Rustagi, Neha; Drexler, Elizabeth S; Slifka, Andrew J

    2014-01-01

    A model to predict fatigue crack growth of API pipeline steels in high pressure gaseous hydrogen has been developed and is presented elsewhere. The model currently has several parameters that must be calibrated for each pipeline steel of interest. This work provides a sensitivity analysis of the model parameters in order to provide (a) insight to the underlying mathematical and mechanistic aspects of the model, and (b) guidance for model calibration of other API steels. PMID:26601024

  4. Sensitivity Analysis of Fatigue Crack Growth Model for API Steels in Gaseous Hydrogen.

    Science.gov (United States)

    Amaro, Robert L; Rustagi, Neha; Drexler, Elizabeth S; Slifka, Andrew J

    2014-01-01

    A model to predict fatigue crack growth of API pipeline steels in high pressure gaseous hydrogen has been developed and is presented elsewhere. The model currently has several parameters that must be calibrated for each pipeline steel of interest. This work provides a sensitivity analysis of the model parameters in order to provide (a) insight to the underlying mathematical and mechanistic aspects of the model, and (b) guidance for model calibration of other API steels.

  5. A RESTful API for accessing microbial community data for MG-RAST.

    Science.gov (United States)

    Wilke, Andreas; Bischof, Jared; Harrison, Travis; Brettin, Tom; D'Souza, Mark; Gerlach, Wolfgang; Matthews, Hunter; Paczian, Tobias; Wilkening, Jared; Glass, Elizabeth M; Desai, Narayan; Meyer, Folker

    2015-01-01

    Metagenomic sequencing has produced significant amounts of data in recent years. For example, as of summer 2013, MG-RAST has been used to annotate over 110,000 data sets totaling over 43 Terabases. With metagenomic sequencing finding even wider adoption in the scientific community, the existing web-based analysis tools and infrastructure in MG-RAST provide limited capability for data retrieval and analysis, such as comparative analysis between multiple data sets. Moreover, although the system provides many analysis tools, it is not comprehensive. By opening MG-RAST up via a web services API (application programmers interface) we have greatly expanded access to MG-RAST data, as well as provided a mechanism for the use of third-party analysis tools with MG-RAST data. This RESTful API makes all data and data objects created by the MG-RAST pipeline accessible as JSON objects. As part of the DOE Systems Biology Knowledgebase project (KBase, http://kbase.us) we have implemented a web services API for MG-RAST. This API complements the existing MG-RAST web interface and constitutes the basis of KBase's microbial community capabilities. In addition, the API exposes a comprehensive collection of data to programmers. This API, which uses a RESTful (Representational State Transfer) implementation, is compatible with most programming environments and should be easy to use for end users and third parties. It provides comprehensive access to sequence data, quality control results, annotations, and many other data types. Where feasible, we have used standards to expose data and metadata. Code examples are provided in a number of languages both to show the versatility of the API and to provide a starting point for users. We present an API that exposes the data in MG-RAST for consumption by our users, greatly enhancing the utility of the MG-RAST service.

  6. A RESTful API for accessing microbial community data for MG-RAST.

    Directory of Open Access Journals (Sweden)

    Andreas Wilke

    2015-01-01

    Full Text Available Metagenomic sequencing has produced significant amounts of data in recent years. For example, as of summer 2013, MG-RAST has been used to annotate over 110,000 data sets totaling over 43 Terabases. With metagenomic sequencing finding even wider adoption in the scientific community, the existing web-based analysis tools and infrastructure in MG-RAST provide limited capability for data retrieval and analysis, such as comparative analysis between multiple data sets. Moreover, although the system provides many analysis tools, it is not comprehensive. By opening MG-RAST up via a web services API (application programmers interface we have greatly expanded access to MG-RAST data, as well as provided a mechanism for the use of third-party analysis tools with MG-RAST data. This RESTful API makes all data and data objects created by the MG-RAST pipeline accessible as JSON objects. As part of the DOE Systems Biology Knowledgebase project (KBase, http://kbase.us we have implemented a web services API for MG-RAST. This API complements the existing MG-RAST web interface and constitutes the basis of KBase's microbial community capabilities. In addition, the API exposes a comprehensive collection of data to programmers. This API, which uses a RESTful (Representational State Transfer implementation, is compatible with most programming environments and should be easy to use for end users and third parties. It provides comprehensive access to sequence data, quality control results, annotations, and many other data types. Where feasible, we have used standards to expose data and metadata. Code examples are provided in a number of languages both to show the versatility of the API and to provide a starting point for users. We present an API that exposes the data in MG-RAST for consumption by our users, greatly enhancing the utility of the MG-RAST service.

  7. Using DLL as Interface between API an VC#.NET Applications

    Directory of Open Access Journals (Sweden)

    Marian DARDALA

    2006-01-01

    Full Text Available This paper presents a solution for using complex Win32API data structures and functions in Visual C# .NET applications. We built DLL (Dynamic Link Library to manage the API functions and data structures and we used DLL modules in a C# application. This is an easier working way compared with the traditional way of importing and managing API’s functions in C# programs.

  8. Hot-stage microscopy for determination of API particles in a formulated tablet.

    Science.gov (United States)

    Simek, Michal; Grünwaldová, Veronika; Kratochvíl, Bohumil

    2014-01-01

    Although methods exist to readily determine the particle size distribution (PSD) of an active pharmaceutical ingredient (API) before its formulation into a final product, the primary challenge is to develop a method to determine the PSD of APIs in a finished tablet. To address the limitations of existing PSD methods, we used hot-stage microscopy to observe tablet disintegration during temperature change and, thus, reveal the API particles in a tablet. Both mechanical and liquid disintegration were evaluated after we had identified optimum milling time for mechanical disintegration and optimum volume of water for liquid disintegration. In each case, hot-stage micrographs, taken before and after the API melting point, were compared with image analysis software to obtain the PSDs. Then, the PSDs of the APIs from the disintegrated tablets were compared with the PSDs of raw APIs. Good agreement was obtained, thereby confirming the robustness of our methodology. The availability of such a method equips pharmaceutical scientists with an in vitro assessment method that will more reliably determine the PSD of active substances in finished tablets.

  9. The Matchmaker Exchange API: automating patient matching through the exchange of structured phenotypic and genotypic profiles.

    Science.gov (United States)

    Buske, Orion J; Schiettecatte, François; Hutton, Benjamin; Dumitriu, Sergiu; Misyura, Andriy; Huang, Lijia; Hartley, Taila; Girdea, Marta; Sobreira, Nara; Mungall, Chris; Brudno, Michael

    2015-10-01

    Despite the increasing prevalence of clinical sequencing, the difficulty of identifying additional affected families is a key obstacle to solving many rare diseases. There may only be a handful of similar patients worldwide, and their data may be stored in diverse clinical and research databases. Computational methods are necessary to enable finding similar patients across the growing number of patient repositories and registries. We present the Matchmaker Exchange Application Programming Interface (MME API), a protocol and data format for exchanging phenotype and genotype profiles to enable matchmaking among patient databases, facilitate the identification of additional cohorts, and increase the rate with which rare diseases can be researched and diagnosed. We designed the API to be straightforward and flexible in order to simplify its adoption on a large number of data types and workflows. We also provide a public test data set, curated from the literature, to facilitate implementation of the API and development of new matching algorithms. The initial version of the API has been successfully implemented by three members of the Matchmaker Exchange and was immediately able to reproduce previously identified matches and generate several new leads currently being validated. The API is available at https://github.com/ga4gh/mme-apis.

  10. An analysis of multifractal characteristics of API time series in Nanjing, China

    Science.gov (United States)

    Shen, Chen-hua; Huang, Yi; Yan, Ya-ni

    2016-06-01

    This paper describes multifractal characteristics of daily air pollution index (API) records in Nanjing from 2001 to 2012. The entire daily API time series is first divided into 12 parts that serve as research objects, and the generalized Hurst exponent is calculated for each series. And then, the multifractal sources are analyzed and singularity spectra are shown. Next, based on a singularity spectrum, the multifractal-characteristics parameters (maximum exponent α0, spectrum width Δ α, and asymmetry Δ αas) are introduced. The results show that the fractality of daily API for each year is multifractal. The multifractal sources originate from both a broad probability density function and different long-range correlations with small and large fluctuations. The strength of the distribution multifractality is stronger than that of the correlation multifractality. The variation in the structure of API time series with increasing years is mainly related to long-range correlations. The structure of API time series in some years is richer. These findings can provide a scientific basis for further probing into the complexity of API.

  11. Caracterización del aceite de semilla de borraja extraído con dióxido de carbono supercrítico

    Directory of Open Access Journals (Sweden)

    Delgado Andújar, A.

    1999-08-01

    Full Text Available The present work is based on a comparative study of the borage seed's oil obtained with supercritical carbon dioxide by means of the conventional extraction using hexane as a solvent. In the optimal working conditions, the results obtained in the extraction with carbon dioxide are comparable to those obtained in the extraction with hexane, although the oil's quality is higher. Therefore, the process of supercritical extraction with carbon dioxide could be more effective than conventional extraction because the solvent removal is not necessary and several steps of the oil refining process can be reduced notably.

    En el presente trabajo se realiza un estudio comparativo de la calidad del aceite de semilla de borraja obtenido con dióxido de carbono supercrítico y mediante extracción convencional empleando hexano como disolvente. La calidad del aceite extraído con dióxido de carbono es superior. En las condiciones óptimas de operación, los rendimientos encontrados en la extracción con dióxido de carbono, son comparables a los obtenidos en la extracción con hexano, si bien la calidad del aceite es superior. Por tanto, el proceso de Extracción Supercrítica con dióxido de carbono, al eliminar la etapa de recuperación del disolvente y simplificar sensiblemente el proceso de refinado del aceite, se presenta como una alternativa competitiva con la extracción convencional.

  12. Modelación simple y operativa de la distribución del carbono orgánico por fracciones físicas en los suelos

    Directory of Open Access Journals (Sweden)

    Fernando Paz

    2016-07-01

    Full Text Available Las emisiones de gases efecto invernadero asociadas al carbono orgánico del suelo (COS son importantes para estudiar cambios en los ecosistemas terrestres. Hay modelos simples que, ofrecen la oportunidad de analizar la dinámica de las alteraciones provocadas por los cambios en el uso de suelo, la vegetación y las prácticas de manejo. En México se dispone de información del COS total y la textura del suelo. En el presente trabajo se analizan diferentes esquemas para parametrizar el modelo COLPOS, el cual se desarrolló para caracterizar la distribución del COS en fracciones físicas del suelo. El modelo considera el COS de diferentes almacenes: materia orgánica particulada (MOP, materia orgánica lábil y complejos organominerales (MO + arena-limo-arcilla. El carbono orgánico inerte (COI, con tiempos medios de residencia de cientos a miles de años, y el tamaño de partícula asociado, permiten precisar los parámetros del modelo COLPOS y determinar las pérdidas potenciales de carbono orgánico del suelo. La validación de los métodos de parametrización del modelo COLPOS permite su implementación operativa empleando solamente la información disponible en México (COS y textura del suelo. La parametrización se desarrolló con base en los datos de experimentos de distribución del carbono asociadas al fraccionamiento físico de los suelos, después de la aplicación de dispersión ultrasónica para lograr fraccionamientos completos.

  13. Simulação e análise dosimétrica de protonterapia e íons de carbono no tratamento do melanoma uveal

    Directory of Open Access Journals (Sweden)

    Marília Tavares Christóvão

    2011-12-01

    Full Text Available OBJETIVO: Este artigo apresenta a avaliação dosimétrica da radioterapia por íons de carbono em comparação à protonterapia. MATERIAIS E MÉTODOS: As simulações computacionais foram elaboradas no código Geant4 (GEometry ANd Tracking. Um modelo de olho discretizado em voxels implementado no sistema Siscodes (sistema computacional para dosimetria em radioterapia foi empregado, em que perfis de dose em profundidade e curvas de isodose foram gerados e superpostos. Nas simulações com feixe de íons de carbono, distintos valores de energia do feixe foram adotados, enquanto nas simulações com feixe de prótons os dispositivos da linha de irradiação foram incluídos e diferentes espessuras do material absorvedor foram aplicadas. RESULTADOS: As saídas das simulações foram processadas e integradas ao Siscodes para gerar as distribuições espaciais de dose no modelo ocular, considerando alterações do posicionamento de entrada do feixe. Os percentuais de dose foram normalizados em função da dose máxima para um feixe em posição de entrada específica, energia da partícula incidente e número de íons de carbono e de prótons incidentes. CONCLUSÃO: Os benefícios descritos e os resultados apresentados contribuem para o desenvolvimento das aplicações clínicas e das pesquisas em radioterapia ocular por íons de carbono e prótons.

  14. Fluxos fluviais de carbono orgânico dissolvido para o complexo estuarino de Paranaguá, Paraná, Brasil

    OpenAIRE

    Libardoni, Bruno Guides

    2013-01-01

    Resumo: O crescimento populacional desordenado e a degradacao excessiva dos recursos naturais, como os cursos d fagua, limitam a sustentabilidade dos sistemas naturais e dos humanos que deles dependem. Dentre os diversos constituintes particulados e dissolvidos, carreados por estes cursos d fagua, encontra-se o Carbono Organico Dissolvido (COD), cujo transporte e ciclo biogeoquimico podem ser transformados e modificados pelas atividades humanas. Este constituinte e de grande importancia nas i...

  15. Procesos de certificación de proyectos de captura de gases de efecto invernadero (GEI En los Mercados Internacionales de Carbono

    Directory of Open Access Journals (Sweden)

    Sabogal Aguilar Javier

    2011-11-01

    Full Text Available En el marco de la mitigación al cambio climático, subyacen dos tipos de mecanismos destinados a disminuir las concentraciones de gases efecto invernadero: en primer lugar, la reducción de emisiones por las fuentes contaminantes; y en segundo lugar, el secuestro o captura de los gases de efecto invernadero (GEI cuantificados en CO2 equivalente en proyectos forestales (conocidos como LULUCF.Los proyectos de mitigación se abordan en el presente artículo por la comparación de los procesos de certificación que deben cumplir los proyectos de captura de gases de efecto invernadero, para acceder a los Mercados Internacionales de Carbono, tanto del Mecanismo de Desarrollo Limpio (MDL adoptado por el Protocolo de Kioto, como de los Mercados Voluntarios de Carbono (MVC.Como resultados, se presenta el aporte al desarrollo sustentable "local y regional": social, económico y ambiental en disponibilidad y mantenimiento de bienes y servicios ambientales; se resaltan las críticas a los esquemas de mercado analizados, y la incidencia del aporte a la sustentabilidad regional y local en la aprobación. De acuerdo con a lo anterior, los mercados voluntarios de carbono resultan ser más acordes con proyectos de pequeña y mediana escala mientras que el mecanismo de desarrollo limpio favorece en mayor medida aquellos proyectos de mediana y gran escala.

  16. Modelo para calculo estimación del carbono en Tipo Forestal Roble-Raulí-Coigüe en la Reserva Nacional Malleco: Chile

    Directory of Open Access Journals (Sweden)

    Norman Moreno Garcia

    2011-12-01

    Full Text Available El objetivo de este trabajo es la selección de un modelo para estimación de carbono en Tipo Forestal Roble-Raulí y Coigüe. La recolección de datos se realizo en la Reserva Nacional Malleco. Cada sitio fue representado por un grupo de 5 parcelas (cuadradas, de lado 35m, superficie 1225m2, ubicadas en un transecto según la pendiente más fuerte. Fueron estimados los volúmenes de madera con y sin corteza de la totalidad de los individuos por medio de funciones para cada especie del tipo forestal en estudio. La cantidad de carbono almacenado a nivel de fuste de las parcelas fue estimada aplicando la función universal de carbono. En cada parcela se contabilizaron los árboles por clase diamétrico de DAP, siendo definidas las clases a partir del DAP mínimo de 3 cm y con una amplitud de 5 cm. Fueron ajustados los modelos de Spurr, Meyer, Stoate, Naslund y Schumacher-Hall. El modelo Schumacher-Hall presento el mejor ajuste de acuerdo a los indicadores estadísticos considerados, además de una mejor distribución de residuales.

  17. blend4php: a PHP API for galaxy.

    Science.gov (United States)

    Wytko, Connor; Soto, Brian; Ficklin, Stephen P

    2017-01-01

    Galaxy is a popular framework for execution of complex analytical pipelines typically for large data sets, and is a commonly used for (but not limited to) genomic, genetic and related biological analysis. It provides a web front-end and integrates with high performance computing resources. Here we report the development of the blend4php library that wraps Galaxy's RESTful API into a PHP-based library. PHP-based web applications can use blend4php to automate execution, monitoring and management of a remote Galaxy server, including its users, workflows, jobs and more. The blend4php library was specifically developed for the integration of Galaxy with Tripal, the open-source toolkit for the creation of online genomic and genetic web sites. However, it was designed as an independent library for use by any application, and is freely available under version 3 of the GNU Lesser General Public License (LPGL v3.0) at https://github.com/galaxyproject/blend4phpDatabase URL: https://github.com/galaxyproject/blend4php.

  18. When API Mass Spectrometry Meets Super Atmospheric Pressure Ion Sources.

    Science.gov (United States)

    Chen, Lee Chuin

    2015-01-01

    In a tutorial paper on the application of free-jet technique for API-MS, John Fenn mentioned that "…for a number of years and a number of reasons, it has been found advantageous in many situations to carry out the ionization process in gas at pressures up to 1000 Torr or more" (Int. J. Mass Spectrom. 200: 459-478, 2000). In fact, the first ESI mass spectrometer constructed by Yamashita and Fenn had a counter-flow curtain gas source at 1050 Torr (ca. 1.4 atm) to sweep away the neutral (J. Phys. Chem. 88: 4451-4459, 1984). For gaseous ionization using electrospray plume, theoretical analysis also shows that "super-atmospheric operation would be more preferable in space-charge-limited situations."(Int. J. Mass Spectrom. 300: 182-193, 2011). However, electrospray and the corona-based chemical ion source (APCI) in most commercial instrument are basically operated under an atmospheric pressure ambient, perhaps out of the concern of safety, convenience and simplicity in maintenance. Running the ion source at pressure much higher than 1 atm is not so common, but had been done by a number of groups as well as in our laboratory. A brief review on these ion sources will be given in this paper.

  19. Mating flights select for symmetry in honeybee drones (Apis mellifera).

    Science.gov (United States)

    Jaffé, Rodolfo; Moritz, Robin F A

    2010-03-01

    Males of the honeybee (Apis mellifera) fly to specific drone congregation areas (DCAs), which virgin queens visit in order to mate. From the thousands of drones that are reared in a single colony, only very few succeed in copulating with a queen, and therefore, a strong selection is expected to act on adult drones during their mating flights. In consequence, the gathering of drones at DCAs may serve as an indirect mate selection mechanism, assuring that queens only mate with those individuals having a better flight ability and a higher responsiveness to the queen's visual and chemical cues. Here, we tested this idea relying on wing fluctuating asymmetry (FA) as a measure of phenotypic quality. By recapturing marked drones at a natural DCA and comparing their size and FA with a control sample of drones collected at their maternal hives, we were able to detect any selection on wing size and wing FA occurring during the mating flights. Although we found no solid evidence for selection on wing size, wing FA was found to be significantly lower in the drones collected at the DCA than in those collected at the hives. Our results demonstrate the action of selection during drone mating flights for the first time, showing that developmental stability can influence the mating ability of honeybee drones. We therefore conclude that selection during honeybee drone mating flights may confer some fitness advantages to the queens.

  20. Energetic feedings influence beeswax production by Apis mellifera L. honeybees

    Directory of Open Access Journals (Sweden)

    Marcela Pedraza Carrillo

    2015-02-01

    Full Text Available The effect of different types of energy feeding (sugar syrup, inverted sugar and juice of sugar-cane on beeswax production and its economic feasibility are evaluated. Twenty beehives of Africanized Apis mellifera were selected, and five were used for each type of feeding. The treatments were T1 (sugar-cane juice, T2 (sugar syrup and T3 (inverted sugar. Feedings was provided by Boardman feeders and the amount was adjusted according to consumption. A layer of beeswax was manually set up into the honeybee nest and beeswax built area was measured weekly. Total reducing sugar, calorimetry, dry matter and ashes of all feedings were analyzed. Data were analyzed by analysis of variance with Tukey’s test to determine differences among averages. The average consumption of inverted sugar was significantly lower than that of other treatments. The highest beeswax production average occurred in the sugar syrup treatment. The highest average of ashes, dry matter and reducing sugar occurred, respectively, in sugar-cane juice, inverted sugar and sugar syrup. Sugar syrup may be an alternative energy source for beeswax production, although sugar-cane juice may be more profitable.

  1. Web API for biology with a workflow navigation system.

    Science.gov (United States)

    Kwon, Yeondae; Shigemoto, Yasumasa; Kuwana, Yoshikazu; Sugawara, Hideaki

    2009-07-01

    DNA Data Bank of Japan (DDBJ) provides Web-based systems for biological analysis, called Web APIs for biology (WABI). So far, we have developed over 20 SOAP services and several workflows that consist of a series of method invocations. In this article, we present newly developed services of WABI, that is, REST-based Web services, additional workflows and a workflow navigation system. Each Web service and workflow can be used as a complete service or a building block for programmers to construct more complex information processing systems. The workflow navigation system aims to help non-programming biologists perform analysis tasks by providing next applicable services on Web browsers according to the output of a previously selected service. With this function, users can apply multiple services consecutively only by following links without any programming or manual copy-and-paste operations on Web browsers. The listed services are determined automatically by the system referring to the dictionaries of service categories, the input/output types of services and HTML tags. WABI and the workflow navigation system are freely accessible at http://www.xml.nig.ac.jp/index.html and http://cyclamen.ddbj.nig.ac.jp/, respectively.

  2. The Influence of Niobium on SSC Resistance in API Steels

    Energy Technology Data Exchange (ETDEWEB)

    Malina, J.; Malina, M.; Novosel-Radovic, V. [Zagreb Univ., Faculty of Metallurgy (Croatia)

    2004-07-01

    Full text of publication follows: Oil country tubular goods are often exposed to aggressive sour environments in oil wells where H{sub 2}S promotes sulfide stress cracking, SSC. This is one of the most dangerous corrosion phenomena characterized by unpredictable and sudden cracking of steel constructions in service. SSC results in a variety of fracture features having a common relationship to the presence of hydrogen in metal and therefore it belongs to hydrogen embrittlement phenomena, HE. For the production of sulfide stress cracking resistant (SSC) tubing from steels included in Group 3 of API Specification 5CT, in this study two experimental Cr-Mo steels (without niobium and with niobium microalloyed) were tested. The influence of Nb precipitates in pipeline steels on the sensitivity to sulfide stress cracking was examined in laboratory experiments using three point bent beam tests. High mechanical properties were achieved through quenching and tempering procedures. Better corrosion resistance of Nb-containing steel is the consequence of microstructural parameters obtained through strengthening mechanism with microalloying element. Besides the usual mechanical, metallographic, SEM and TEM analyses, as complementary method the X-ray diffraction was used. It was revealed that tetragonality of crystal lattice, dislocation density and residual stresses are in good correlation with Sc-vales from corrosion tests. Nb precipitates (especially niobium carbides) have beneficial influence when producing the steels with low sensitivity to SSC. (authors)

  3. SIP APIs for Voice and Video Communications on the Web

    CERN Document Server

    Davids, Carol; Singh, Kundan; Sinnreich, Henry; Wimmreuter, Wilhelm

    2011-01-01

    Existing standard protocols for the web and Internet telephony fail to deliver real-time interactive communication from within a web browser. In particular, the client-server web protocol over reliable TCP is not always suitable for end-to-end low latency media path needed for interactive voice and video communication. To solve this, we compare the available platform options using the existing technologies such as modifying the web programming language and protocol, using an existing web browser plugin, and a separate host resident application that the web browser can talk to. We argue that using a separate application as an adaptor is a promising short term as well as long-term strategy for voice and video communications on the web. Our project aims at developing the open technology and sample implementations for web-based real-time voice and video communication applications. We describe the architecture of our project including (1) a RESTful web communication API over HTTP inspired by SIP message flows, (2)...

  4. Nosema Tolerant Honeybees (Apis mellifera) Escape Parasitic Manipulation of Apoptosis

    Science.gov (United States)

    Kurze, Christoph; Le Conte, Yves; Dussaubat, Claudia; Erler, Silvio; Kryger, Per; Lewkowski, Oleg; Müller, Thomas; Widder, Miriam; Moritz, Robin F. A.

    2015-01-01

    Apoptosis is not only pivotal for development, but also for pathogen defence in multicellular organisms. Although numerous intracellular pathogens are known to interfere with the host’s apoptotic machinery to overcome this defence, its importance for host-parasite coevolution has been neglected. We conducted three inoculation experiments to investigate in the apoptotic respond during infection with the intracellular gut pathogen Nosema ceranae, which is considered as potential global threat to the honeybee (Apis mellifera) and other bee pollinators, in sensitive and tolerant honeybees. To explore apoptotic processes in the gut epithelium, we visualised apoptotic cells using TUNEL assays and measured the relative expression levels of subset of candidate genes involved in the apoptotic machinery using qPCR. Our results suggest that N. ceranae reduces apoptosis in sensitive honeybees by enhancing inhibitor of apoptosis protein-(iap)-2 gene transcription. Interestingly, this seems not be the case in Nosema tolerant honeybees. We propose that these tolerant honeybees are able to escape the manipulation of apoptosis by N. ceranae, which may have evolved a mechanism to regulate an anti-apoptotic gene as key adaptation for improved host invasion. PMID:26445372

  5. Nosema Tolerant Honeybees (Apis mellifera Escape Parasitic Manipulation of Apoptosis.

    Directory of Open Access Journals (Sweden)

    Christoph Kurze

    Full Text Available Apoptosis is not only pivotal for development, but also for pathogen defence in multicellular organisms. Although numerous intracellular pathogens are known to interfere with the host's apoptotic machinery to overcome this defence, its importance for host-parasite coevolution has been neglected. We conducted three inoculation experiments to investigate in the apoptotic respond during infection with the intracellular gut pathogen Nosema ceranae, which is considered as potential global threat to the honeybee (Apis mellifera and other bee pollinators, in sensitive and tolerant honeybees. To explore apoptotic processes in the gut epithelium, we visualised apoptotic cells using TUNEL assays and measured the relative expression levels of subset of candidate genes involved in the apoptotic machinery using qPCR. Our results suggest that N. ceranae reduces apoptosis in sensitive honeybees by enhancing inhibitor of apoptosis protein-(iap-2 gene transcription. Interestingly, this seems not be the case in Nosema tolerant honeybees. We propose that these tolerant honeybees are able to escape the manipulation of apoptosis by N. ceranae, which may have evolved a mechanism to regulate an anti-apoptotic gene as key adaptation for improved host invasion.

  6. Cytosine modifications in the honey bee (Apis mellifera worker genome

    Directory of Open Access Journals (Sweden)

    Erik Magne Koscielniak Rasmussen

    2015-02-01

    Full Text Available Epigenetic changes enable genomes to respond to changes in the environment, such as altered nutrition, activity, or social setting. Epigenetic modifications, thereby, provides a source of phenotypic plasticity in many species. The honey bee (Apis mellifera uses nutritionally sensitive epigenetic control mechanisms in the development of the royal caste (queens and the workers. The workers are functionally sterile females that can take on a range of distinct physiological and/or behavioral phenotypes in response to environmental changes. Honey bees have a wide repertoire of epigenetic mechanisms which, as in mammals, includes cytosine methylation, hydroxymethylated cytosines, together with the enzymatic machinery responsible for these cytosine modifications. Current data suggests that honey bees provide an excellent system for studying the social repertoire of the epigenome. In this review, we elucidate what is known so far about the honey bee epigenome and its mechanisms. Our discussion includes what may distinguish honey bees from other model animals, how the epigenome can influence worker behavioral task separation, and how future studies can answer central questions about the role of the epigenome in social behavior.

  7. blend4php: a PHP API for galaxy

    Science.gov (United States)

    Wytko, Connor; Soto, Brian; Ficklin, Stephen P.

    2017-01-01

    Galaxy is a popular framework for execution of complex analytical pipelines typically for large data sets, and is a commonly used for (but not limited to) genomic, genetic and related biological analysis. It provides a web front-end and integrates with high performance computing resources. Here we report the development of the blend4php library that wraps Galaxy’s RESTful API into a PHP-based library. PHP-based web applications can use blend4php to automate execution, monitoring and management of a remote Galaxy server, including its users, workflows, jobs and more. The blend4php library was specifically developed for the integration of Galaxy with Tripal, the open-source toolkit for the creation of online genomic and genetic web sites. However, it was designed as an independent library for use by any application, and is freely available under version 3 of the GNU Lesser General Public License (LPGL v3.0) at https://github.com/galaxyproject/blend4php. Database URL: https://github.com/galaxyproject/blend4php PMID:28077564

  8. Activity of telomerase and telomeric length in Apis mellifera.

    Science.gov (United States)

    Korandová, Michala; Frydrychová, Radmila Čapková

    2016-06-01

    Telomerase is an enzyme that adds repeats of DNA sequences to the ends of chromosomes, thereby preventing their shortening. Telomerase activity is associated with proliferative status of cells, organismal development, and aging. We report an analysis of telomerase activity and telomere length in the honeybee, Apis mellifera. Telomerase activity was found to be regulated in a development and caste-specific manner. During the development of somatic tissues of larval drones and workers, telomerase activity declined to 10 % of its level in embryos and remained low during pupal and adult stages but was upregulated in testes of late pupae, where it reached 70 % of the embryo level. Upregulation of telomerase activity was observed in the ovaries of late pupal queens, reaching 160 % of the level in embryos. Compared to workers and drones, queens displayed higher levels of telomerase activity. In the third larval instar of queens, telomerase activity reached the embryo level, and an enormous increase was observed in adult brains of queens, showing a 70-fold increase compared to a brain of an adult worker. Southern hybridization of terminal TTAGG fragments revealed a high variability of telomeric length between different individuals, although the same pattern of hybridization signals was observed in different tissues of each individual.

  9. Mating flights select for symmetry in honeybee drones ( Apis mellifera)

    Science.gov (United States)

    Jaffé, Rodolfo; Moritz, Robin F. A.

    2010-03-01

    Males of the honeybee ( Apis mellifera) fly to specific drone congregation areas (DCAs), which virgin queens visit in order to mate. From the thousands of drones that are reared in a single colony, only very few succeed in copulating with a queen, and therefore, a strong selection is expected to act on adult drones during their mating flights. In consequence, the gathering of drones at DCAs may serve as an indirect mate selection mechanism, assuring that queens only mate with those individuals having a better flight ability and a higher responsiveness to the queen’s visual and chemical cues. Here, we tested this idea relying on wing fluctuating asymmetry (FA) as a measure of phenotypic quality. By recapturing marked drones at a natural DCA and comparing their size and FA with a control sample of drones collected at their maternal hives, we were able to detect any selection on wing size and wing FA occurring during the mating flights. Although we found no solid evidence for selection on wing size, wing FA was found to be significantly lower in the drones collected at the DCA than in those collected at the hives. Our results demonstrate the action of selection during drone mating flights for the first time, showing that developmental stability can influence the mating ability of honeybee drones. We therefore conclude that selection during honeybee drone mating flights may confer some fitness advantages to the queens.

  10. Comparative sucrose responsiveness in Apis mellifera and A. cerana foragers.

    Science.gov (United States)

    Yang, Wenchao; Kuang, Haiou; Wang, Shanshan; Wang, Jie; Liu, Wei; Wu, Zhenhong; Tian, Yuanyuan; Huang, Zachary Y; Miao, Xiaoqing

    2013-01-01

    In the European honey bee, Apis mellifera, pollen foragers have a higher sucrose responsiveness than nectar foragers when tested using a proboscis extension response (PER) assay. In addition, Africanized honey bees have a higher sucrose responsiveness than European honey bees. Based on the biology of the Eastern honey bee, A. cerana, we hypothesized that A. cerana should also have a higher responsiveness to sucrose than A. mellifera. To test this hypothesis, we compared the sucrose thresholds of pollen foragers and nectar foragers in both A. cerana and A. mellifera in Fujian Province, China. Pollen foragers were more responsive to sucrose than nectar foragers in both species, consistent with previous studies. However, contrary to our hypothesis, A. mellifera was more responsive than A. cerana. We also demonstrated that this higher sucrose responsiveness in A. mellifera was not due to differences in the colony environment by co-fostering two species of bees in the same mixed-species colonies. Because A. mellifera foragers were more responsive to sucrose, we predicted that their nectar foragers should bring in less concentrated nectar compared to that of A. cerana. However, we found no differences between the two species. We conclude that A. cerana shows a different pattern in sucrose responsiveness from that of Africanized bees. There may be other mechanisms that enable A. cerana to perform well in areas with sparse nectar resources.

  11. Western honeybee drones and workers (Apis mellifera ligustica) have different olfactory mechanisms than eastern honeybees (Apis cerana cerana).

    Science.gov (United States)

    Woltedji, Dereje; Song, Feifei; Zhang, Lan; Gala, Alemayehu; Han, Bin; Feng, Mao; Fang, Yu; Li, Jianke

    2012-09-07

    The honeybees Apis mellifera ligustica (Aml) and Apis cerana cerana (Acc) are two different western and eastern bee species that evolved in distinct ecologies and developed specific antennal olfactory systems for their survival. Knowledge of how their antennal olfactory systems function in regards to the success of each respective bee species is scarce. We compared the antennal morphology and proteome between respective sexually mature drones and foraging workers of both species using a scanning electron microscope, two-dimensional electrophoresis, mass spectrometry, bioinformatics, and quantitative real-time polymerase chain reaction. Despite the general similarities in antennal morphology of the drone and worker bees between the two species, a total of 106 and 100 proteins altered their expression in the drones' and the workers' antennae, respectively. This suggests that the differences in the olfactory function of each respective bee are supported by the change of their proteome. Of the 106 proteins that altered their expression in the drones, 72 (68%) and 34 (32%) were overexpressed in the drones of Aml and Acc, respectively. The antennae of the Aml drones were built up by the highly expressed proteins that were involved in carbohydrate metabolism and energy production, molecular transporters, antioxidation, and fatty acid metabolism in contrast to the Acc drones. This is believed to enhance the antennal olfactory functions of the Aml drones as compared to the Acc drones during their mating flight. Likewise, of the 100 proteins with expression changes between the worker bees of the two species, 67% were expressed in higher levels in the antennae of Aml worker contrasting to 33% in the Acc worker. The overall higher expressions of proteins related to carbohydrate metabolism and energy production, molecular transporters, and antioxidation in the Aml workers compared with the Acc workers indicate the Aml workers require more antennal proteins for their olfactory

  12. The construction of prokaryotic expression system for human Api6 fusion protein%人Api6融合蛋白原核表达系统的构建

    Institute of Scientific and Technical Information of China (English)

    方严; 练雪梅

    2011-01-01

    Objective:To further study the pathophysiological function of human Api6 fusion protein expression using a prokaryotic expression system. Methods: Api6 cDNA was inserted into ppSUMO vector to form recombinant plasmid pp-SUMO-Api6;recombinant plasmid ppSUMO-Api6 was trans-formed into prokaryotic expression host E.coli Rosetta;prokaryotic expression method was optimized to induce expression of recombi-nant protein Api6 in different conditions of E.coli density,temperature,IPTG concentration and induction time;recombinant protein Api6 was identified by Western blot. Results:The recombinant plasmid ppSUMO-Api6 was successfully constructed;the recombinant protein Api6 was successfully induced,and the expression of recombinant protein ppSUMO-Api6 from the prokaryotic expression system was optimized in the condition of OD600=0.5-0.8,16℃,0.5 mmol/L IPTG and 16 h induction.Conclusion:Recombinant plasmid ppSUMO-Api6 was converted into the prokaryotic expression host E.coli Rosetta to get the recombinant strain ppSUMO-Api6-Rosetta.Recombinant protein ppSUMO-Api6 was expressed using a prokaryotic expression system at the optimal expression conditions.%目的:本研究拟采用蛋白原核表达的方法,诱导表达人Api6(Apoptosis inhibitor 6)融合蛋白,为进一步研究Api6在凋亡抑制、脂质代谢和肿瘤发生中的作用奠定基础.方法:利用PCR技术扩增人Api6基因,将其克隆至原核表达载体ppSUMO,构建重组质粒ppSUMO-Api6;重组质粒转化原核表达宿主菌E.coli Rosetta感受态;采用蛋白原核表达的方法,不同诱导前菌液浓度,不同温度、不同异丙基硫化半乳糖苷(Isopropy 1-β-D-thiogalaotopyrano-side,IPTG)浓度、不同诱导时间,筛选诱导表达Api6重组蛋白的最优条件;Western blot鉴定其表达情况.结果:成功构建重组质粒ppSUMO-Api6;成功诱导Api6重组蛋白的原核表达,表达的最优条件为:OD600=0.5~0.8的重组菌,16℃、0.5 mmol/L IPTG诱导16 h.结论:含有人Api6 c

  13. Fraccionamiento químico del carbono en suelos con diferentes usos en el departamento de Magdalena, Colombia

    Directory of Open Access Journals (Sweden)

    José Rafael Vásquez Polo

    2017-01-01

    Full Text Available El cambio en el uso y manejo de los suelos puede afectar su capacidad para capturar carbono, cuya magnitud es desconocida en la región norte del departamento de Magdalena, Colombia. En este sentido es importante avanzar en estudios de caracterización cualitativa de la materia orgánica del suelo y el efecto que sobre ella han tenido los cambios de uso y el manejo de suelos dedicados al monocultivo. Por tal motivo se estudió la relación de los diferentes usos del suelo sobre los contenidos y formas de carbono (C en seis zonas edafoclimáticas al norte de dicho departamento, ubicado entre 5 y 956 m de altitud, con temperaturas medias entre 24 y 30 °C y precipitaciones medias entre 663 y 2000 mm. En cada zona se muestrearon dos sitios, cultivos tropicales y bosques (húmedos y secos tropicales, tomando cuatro muestras compuestas por diez submuestras aleatorias por sitio, en las que se determinó C total (Ct, C oxidable total (Cox, C hidrolizable con HCl 6N (Ch, C ligado al material húmico (Cp mediante extracción con pirofosfato sódico y C no oxidable (Cnox o C recalcitrante calculado como la diferencia Ct-Cox. El C total almacenado (Cta por unidad de superficie se calculó teniendo en cuenta la densidad aparente (Da y la profundidad de muestreo. Se encontraron diferencias estadísticas significativas por el efecto de las zonas, los valores mayores en porcentaje de Nt (0.32, Ct (3.90, Cox (3.85, Ch (2.05 y Cp (1.15 y Cta (109 Mg ha-1 se presentaron en los suelos de bosque húmedo de la zona 1, siendo la de mayor altitud (956 m, precipitación (2000 mm y menor temperatura (24 °C. Para el factor usos del suelo solo presentaron diferencias significativas las propiedades: Nt, Ct, Cox y Ch. Los valores de las formas de C más estables para los suelos de bosques, superaron los de los suelos de cultivo, en este contexto, Cox y Cnox representaron 95% y 5% del Ct, respectivamente Se observó en promedio una pérdida de 26% del Ct en suelos de

  14. Depósito de capas de nitruro de carbono mediante ablación láser

    Directory of Open Access Journals (Sweden)

    Soto, R.

    1998-04-01

    Full Text Available The preparation of carbon nitride thin films by ablation of different target compounds (graphite, guanazole in a reactive atmosphere of ammonia with an ArF excimer laser (193 nm is reported. The films were deposited on different substrates (silicon wafers and aluminium plates and were analysed with different techniques such as profilometry, Fourier transform infrared (FTIR and energy dispersive X-ray spectroscopy (EDX. For both targets, a comparative study of the influence of the ammonia total pressure on the growth rate, composition and properties of the obtained material has been done. A gradual nitrogen incorporation in the films with increasing ammonia pressure and also the presence of nitrogen bonded to carbon in different configurations (simple, double and/or triple bonds was observed. The use of guanazole targets leads to higher efficiency in the nitrogen incorporation and in the formation of simple C-N bonds.

    Se presenta la preparación de capas finas de nitruro de carbono mediante la ablación de diferentes tipos de blancos (grafito, guanazol en una atmósfera reactiva de amoniaco utilizando un láser de excímero de ArF (193 nm. Las capas se han depositado sobre diferentes soportes (obleas de silicio y aluminio y se han analizado empleando técnicas de caracterización básicas como la espectroscopia infrarroja mediante transformada de Fourier (FTIR, espectroscopia de rayos X por dispersión de energía (EDX y perfilometría. Se ha realizado, para los dos blancos utilizados, un estudio comparativo de la influencia de la presión total de amoniaco en la velocidad de depósito, composición y propiedades del material obtenido. Se ha observado en ambos casos la progresiva incorporación de nitrógeno en las capas con el aumento de la presión de amoniaco, estando el nitrógeno enlazado al carbono en diferentes configuraciones (enlaces simples, dobles y/o triples. La utilización del blanco de guanazol se muestra más eficiente en

  15. Evaluación preliminar del potencial de indicadores de salud y calidad relacionados con el ciclo del carbono de suelos del humedal de Jaboque (Cundinamarca, Colombia

    Directory of Open Access Journals (Sweden)

    Pulido Barrios Hannier Wadith

    2006-06-01

    Full Text Available En el presente trabajo se evaluó el potencial de las actividades enzimáticas celulasa y ‚glucosidasa, de la
    biomasa microbiana por carbono, del porcentaje de carbono orgánico total y del pH en suelos y sedimentos aledaños al humedal de Jaboque (Bogotá-Colombia para determinar su posible utilidad como indicadores del estado de salud y calidad. Para ello se evaluaron los resultados obtenidos en dos épocas del año y en nueve puntos del humedal, que corresponden a problemáticas específicas: cuatro de ellos son suelos, dos son de carácter agrícola, mientras que los cinco puntos restantes son sedimentos. El análisis estadístico de los datos se realizó por el método no paramétrico de Kruskal-Wallis (p=0,05 arrojando diferencias significativas entre los diferentes puntos del humedal y los diferentes tiempos de muestreo, excepto para el parámetro ecofisiológico tasa metabólica (qCO2. La biomasa por carbono en general se relaciona con la respiración y el porcentaje de acumulación de la materia orgánica. Se encontró que las actividades enzimáticas junto con los otros parámetros medidos, exceptuando la tasa metabólica varían significativamente en los distintos puntos
    de muestreo y en las dos épocas de muestreo. Para todos los puntos de muestreo se hizo una aproximación al estado de los procesos involucrados en el ciclo de carbono en el humedal. Los porcentajes de carbono orgánico son significativamente altos, lo que estaría implicando una eutrofización generalizada para todo el humedal. Las diferencias significativas encontradas en los parámetros medidos dan cuenta de la sensibilidad de éstos al problema de contaminación del humedal.

  16. Carbono orgánico en suelos agrícolas de México: investigación y políticas públicas

    Directory of Open Access Journals (Sweden)

    Helena Cotler

    2016-03-01

    Full Text Available El análisis de una extensa revisión bibliográfica sobre la investigación en conservación de carbono en suelos de México muestra que prácticas de agricultura de conservación y diversos sistemas de producción tradicionales pueden incrementar de manera considerable el carbono orgánico en suelos, lo que repercute en su resistencia ante el impacto de la lluvia, mejora la tasa de infiltración y la cantidad de agua disponible, incrementa el contenido de la biomasa microbiana, disminuye la erosión y mitiga la emisión de gases de efecto invernadero. La relevancia que adquiere la calidad de los suelos en la seguridad alimentaria y en los impactos ambientales, incluyendo el cambio climático, explica la importancia de su incorporación en las políticas públicas del país. Sin embargo, la revisión de instrumentos de política pública del presente sexenio (2013-2018 expone grandes vacíos y contradicciones que se presentan a través de ejemplos concretos de acciones. El escaso presupuesto destinado a la conservación de suelos (2.12% del presupuesto total de SAGARPA en 2014 aplicado mayormente (más de 80% a infraestructura hidráulica señala por un lado, la ausencia del reconocimiento del suelo como medio para infiltrar y retener agua; y por el otro, la incipiente incorporación de los estudios sobre carbono en suelos en los instrumentos de política pública correspondientes. Se identifican varios aspectos necesarios para mejorar la transversalidad en torno a la conservación de carbono en suelos: (i generar políticas públicas que reconozcan las funciones y los servicios ecosistémicos que proveen los suelos, (ii fortalecer la institucionalidad acerca del tema de suelos, (iii incentivar los programas de conservación de suelos in situ, que incorporen carbono a través de la promoción de agroecosistemas adaptados a las diversas condiciones territoriales.

  17. Comparison of API 20E and invA PCR for identification of Salmonella enterica isolates from swine production units.

    Science.gov (United States)

    Nucera, Daniele M; Maddox, Carol W; Hoien-Dalen, Patricia; Weigel, Ronald M

    2006-09-01

    API 20E and invA PCR were evaluated for the identification of Salmonella enterica isolates from swine farms. API 20E had the highest agreement with other tests at the 99.9% likelihood level. Both tests had 100% sensitivity and 96% specificity compared to 16S rRNA sequencing. Compared to serotyping, both tests had 96% sensitivity; specificity was 86% for API 20E and 79% for invA PCR.

  18. Mutational epitope analysis and cross-reactivity of two isoforms of Api g 1, the major celery allergen.

    Science.gov (United States)

    Wangorsch, Andrea; Ballmer-Weber, Barbara K; Rösch, Paul; Holzhauser, Thomas; Vieths, Stefan

    2007-04-01

    For better understanding the cross-reactivity between the major birch pollen and celery allergens, Bet v 1 and Api g 1, respectively, putative epitope areas and structurally important positions for IgE-binding of the isoforms Api g 1.01 and Api g 1.02 were point mutated. The IgE binding capacities were measured in ELISA, the IgE cross-reactivity between the isoforms, mutants and Bet v 1 investigated by ELISA-inhibition experiments with serum pools from patients with confirmed celery allergy (DBPCFC). Api g 1.01 displayed a clearly higher frequency and capacity of IgE binding than Api g 1.02. In Api g 1.01, substitution of lysine against glutamic acid at amino acid position 44, a key residue of the Bet v 1 "P-loop", increased the IgE-binding properties. Structural instability due to proline insertion at position 111/112 resulted in loss of IgE binding of Api g 1.01, but not of Api g 1.02. Between Api g 1.01 and Api g 1.02 only partial cross-reactivity was seen. The data suggest that the IgE epitopes of the two isoforms are distinct and that in contrast to Api g 1.01, the "P-loop" region plays an important role for IgE binding of celery allergic subjects to Api g 1.02. Understanding and investigation of the molecular mechanisms in celery allergy is an important step to generate hypoallergenic proteins for safe and efficacious immunotherapy of food allergy.

  19. Software Defined GPS API: Development and Implementation of GPS Correlator Architectures Using MATLAB with Focus on SDR Implementations

    Science.gov (United States)

    2014-05-18

    NO. 0704-0188 3. DATES COVERED (From - To) - UU UU UU UU Approved for public release; distribution is unlimited. Software Defined GPS API : Development...and Implementation of GPS Correlator Architectures Using MATLAB with Focus on SDR Implementations The Software Defined GPS API was created with the...ABOVE ADDRESS. Polytechnic University of Puerto Rico 377 Ponce de Leon Ave. Hato Rey, PR 00918 -0000 ABSTRACT Software Defined GPS API : Development and

  20. Windows API funkcijų sekų perėmimo bibliotekų tyrimas Windows API Hooking Libraries Research

    Directory of Open Access Journals (Sweden)

    Lukas Radvilavičius

    2011-08-01

    Full Text Available

    Nagrinėjamos bibliotekos, skirtos Windows API funkcijų sekų perėmimui. Sekų perėmimas gali būti panaudojamas įvairiose srityse: siekiant išsiaiškinti operacinės sistemos veikimo principus, norint atlikti programos derinimą arba pridėti papildomą funkcionalumą prie jau esamo. Straipsnyje apžvelgiamos Windows API ir pateikiamos trečiųjų šalių priemonės funkcijų sekoms  perimti. Aptariamos jų teikiamos galimybės, panaudojimo specifika. Taip pat atlikti testai, siekiant išsiaiškinti, kuri biblioteka su užduotimis susitvarko greičiausiai. Tyrimui pasirinkti du nemokami gaminiai: Microsoft Detours ir EasyHook bibliotekos.

    Straipsnis lietuvių kalba

    The paper describes methods how to apply Windows API hooking with third party libraries and solutions. In this research were used Windows API function SetWindowsHookEx, Detours and EasyHook libraries. Libraries methods, features and advantages were discussed in this paper. The practical part contains libraries tests. In analysis we tested target program start with hooking library and injected function call.

    Article in Lithuanian

  1. Development of API 5 CT grade P110 steel casing; Desenvolvimento de tubos casing API 5 CT grau P110

    Energy Technology Data Exchange (ETDEWEB)

    Kojima, Sergio Seijo; Roza, Juliana Espinossi

    2003-07-01

    This paper has as objective to discuss the results gotten in experiences carried through in industrial scale for the development of pipes class API 5CT P110 (1), with 244 mm of diameter and 12 mm of thickness. The pipes were welded longitudinally by process ERW (electric resistance welding) and submitted to quenching and tempering heat treatments. A C-Mn-Cr alloy with adequate quenching ability was used for the attainment of a martensite microstructure after quenching. The pipes at a temperature of 880 deg C were quenched in water and subsequently tempered at 515 deg C. The integrity of the weld region was evaluated through non destructive tests and flattening tests, Charpy impact tests and fracture toughness tests (CTOD). The pipes achieved the tension properties stipulated in the standard (yield strength bigger limit of 758 Mpa), and also the energy in the Charpy impact test (transversal), considering that the energy value obtained was 55 J (at 0 deg C) for base metal and 44 J in the weld metal. (author)

  2. [Melissopalynology and trophic niche of Apis cerana ceraca and Apis mellifera ligustica in Yunnan Province of Southwest China].

    Science.gov (United States)

    Liu, Yu-Jia; Zhao, Tian-Rui; Zhao, Feng-Yun

    2013-01-01

    In 2010 and 2011, the honey samples of Apis cerana cerana and A. mellifera ligustica were collected from Kunming and Mengzi of Yunnan Province, respectively, aimed to analyze the melissopalynology and tropic niche of the two bee species. The absolute pollen concentration of the honey of A. cerana cerana was 1.55 x 10(4) ind x g(-1), being significantly higher than that (1.01 x 10(4) ind x g(-1)) of A. mellifera ligustica, and the number of nectar plant species collected by A. cerana cerana was 12.9, also significantly higher than that (7.7) collected by A. mellifera ligustica, indicating that A. cerana cerana could utilize more nectar plants, while A. mellifera ligustica had stronger selectivity to the nectar plants. The trophic niche breadth of A. cerana cerana was 0.35, which was significantly higher than that (0.23) of A. mellifera ligustica. The trophic niche overlap index between the two bee species was 0.71, and the interspecific competition index was 0.93, suggesting that the food competition between A. cerana cerana and A. mellifera ligustica was fierce.

  3. 一种基于新型图模型的 API 推荐系统%APISynth:A New Graph-Based API Recommender System

    Institute of Scientific and Technical Information of China (English)

    吕晨; 姜伟; 虎嵩林

    2015-01-01

    对象实例化是软件工程类库复用中一个常见、复杂的问题.即根据已知源类型的对象,用户需要编写代码对目标类型进行实例化.研究人员提出了若干种 API 自动推荐系统辅助用户解决上述问题.然而这些系统不能同时兼顾准确率和查全率,因此在一定程度上影响了系统的实用性.该文提出了一种兼顾准确率和查全率,基于新型图模型的 API 推荐系统———APISynth.在查全率方面,APISynth 使用一个新颖的全局图模型来表达类库中所有的API 依赖关系和 API 历史使用信息.利用新的全局图模型具有的特殊 Tag 元素和可达性质以避免错误的 API 调用.在准确率方面,APISynth 首先将对象实例化问题建模为 Top-K 子图查询问题,然后设计一种新的支持 DAG 形式解的图搜索算法,避免了传统的最短路径图搜索算法导致的查不准问题.实验结果表明,与现有多种方法相比, APISynth 在准确率和查全率两方面均获得了较大提升.%How to perform object instantiation is a common and complex problem in reusing an existing library.In this problem,given the object of source type,users need to write code to instantiate the destination type.Recently,researchers have proposed a variety of related API automatic recommender systems to fulfill this problem.These systems can assist users to solve the above issue in some degree.However,it is very difficult for such systems to achieve both good recall and precision,which affects the usability.This paper presents APISynth,a new graph-based API recommender system.In order to improve the recall,APISynth utilizes a new global graph model to give a better representation for the API dependencies in the relevant class library,and to include API historical usage information in.A special tag element is added to the new graph together with a new reach ability property to avoid false invocation of APIs

  4. Transcriptome analysis of the Asian honey bee Apis cerana cerana.

    Directory of Open Access Journals (Sweden)

    Zi Long Wang

    Full Text Available BACKGROUND: The Eastern hive honey bee, Apis cerana cerana is a native and widely bred honey bee species in China. Molecular biology research about this honey bee species is scarce, and genomic information for A. c. cerana is not currently available. Transcriptome and expression profiling data for this species are therefore important resources needed to better understand the biological mechanisms of A. c. cerana. In this study, we obtained the transcriptome information of A. c. cerana by RNA-sequencing and compared gene expression differences between queens and workers of A. c. cerana by digital gene expression (DGE analysis. RESULTS: Using high-throughput Illumina RNA sequencing we obtained 51,581,510 clean reads corresponding to 4.64 Gb total nucleotides from a single run. These reads were assembled into 46,999 unigenes with a mean length of 676 bp. Based on a sequence similarity search against the five public databases (NR, Swissport, GO, COG, KEGG with a cut-off E-value of 10(-5 using BLASTX, a total of 24,630 unigenes were annotated with gene descriptions, gene ontology terms, or metabolic pathways. Using these transcriptome data as references we analyzed the gene expression differences between the queens and workers of A. c. cerana using a tag-based digital gene expression method. We obtained 5.96 and 5.66 million clean tags from the queen and worker samples, respectively. A total of 414 genes were differentially expressed between them, with 189 up-regulated and 225 down-regulated in queens. CONCLUSIONS: Our transcriptome data provide a comprehensive sequence resource for future A. c. cerana study, establishing an important public information platform for functional genomic studies in A. c. cerana. Furthermore, the DGE data provide comprehensive gene expression information for the queens and workers, which will facilitate our understanding of the molecular mechanisms of the different physiological aspects of the two castes.

  5. Social waves in giant honeybees (Apis dorsata) elicit nest vibrations.

    Science.gov (United States)

    Kastberger, Gerald; Weihmann, Frank; Hoetzl, Thomas

    2013-07-01

    Giant honeybees (Apis dorsata) nest in the open and have developed a wide array of strategies for colony defence, including the Mexican wave-like shimmering behaviour. In this collective response, the colony members perform upward flipping of their abdomens in coordinated cascades across the nest surface. The time-space properties of these emergent waves are response patterns which have become of adaptive significance for repelling enemies in the visual domain. We report for the first time that the mechanical impulse patterns provoked by these social waves and measured by laser Doppler vibrometry generate vibrations at the central comb of the nest at the basic (='natural') frequency of 2.156 ± 0.042 Hz which is more than double the average repetition rate of the driving shimmering waves. Analysis of the Fourier spectra of the comb vibrations under quiescence and arousal conditions provoked by mass flight activity and shimmering waves gives rise to the proposal of two possible models for the compound physical system of the bee nest: According to the elastic oscillatory plate model, the comb vibrations deliver supra-threshold cues preferentially to those colony members positioned close to the comb. The mechanical pendulum model predicts that the comb vibrations are sensed by the members of the bee curtain in general, enabling mechanoreceptive signalling across the nest, also through the comb itself. The findings show that weak and stochastic forces, such as general quiescence or diffuse mass flight activity, cause a harmonic frequency spectrum of the comb, driving the comb as an elastic plate. However, shimmering waves provide sufficiently strong forces to move the nest as a mechanical pendulum. This vibratory behaviour may support the colony-intrinsic information hypothesis herein that the mechanical vibrations of the comb provoked by shimmering do have the potential to facilitate immediate communication of the momentary defensive state of the honeybee nest to

  6. Viruses associated with ovarian degeneration in Apis mellifera L. queens.

    Directory of Open Access Journals (Sweden)

    Laurent Gauthier

    Full Text Available Queen fecundity is a critical issue for the health of honeybee (Apis mellifera L. colonies, as she is the only reproductive female in the colony and responsible for the constant renewal of the worker bee population. Any factor affecting the queen's fecundity will stagnate colony development, increasing its susceptibility to opportunistic pathogens. We discovered a pathology affecting the ovaries, characterized by a yellow discoloration concentrated in the apex of the ovaries resulting from degenerative lesions in the follicles. In extreme cases, marked by intense discoloration, the majority of the ovarioles were affected and these cases were universally associated with egg-laying deficiencies in the queens. Microscopic examination of the degenerated follicles showed extensive paracrystal lattices of 30 nm icosahedral viral particles. A cDNA library from degenerated ovaries contained a high frequency of deformed wing virus (DWV and Varroa destructor virus 1 (VDV-1 sequences, two common and closely related honeybee Iflaviruses. These could also be identified by in situ hybridization in various parts of the ovary. A large-scale survey for 10 distinct honeybee viruses showed that DWV and VDV-1 were by far the most prevalent honeybee viruses in queen populations, with distinctly higher prevalence in mated queens (100% and 67%, respectively for DWV and VDV-1 than in virgin queens (37% and 0%, respectively. Since very high viral titres could be recorded in the ovaries and abdomens of both functional and deficient queens, no significant correlation could be made between viral titre and ovarian degeneration or egg-laying deficiency among the wider population of queens. Although our data suggest that DWV and VDV-1 have a role in extreme cases of ovarian degeneration, infection of the ovaries by these viruses does not necessarily result in ovarian degeneration, even at high titres, and additional factors are likely to be involved in this pathology.

  7. Detection of Illicit Drugs by Trained Honeybees (Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Matthias Schott

    Full Text Available Illegal drugs exacerbate global social challenges such as substance addiction, mental health issues and violent crime. Police and customs officials often rely on specially-trained sniffer dogs, which act as sensitive biological detectors to find concealed illegal drugs. However, the dog "alert" is no longer sufficient evidence to allow a search without a warrant or additional probable cause because cannabis has been legalized in two US states and is decriminalized in many others. Retraining dogs to recognize a narrower spectrum of drugs is difficult and training new dogs is time consuming, yet there are no analytical devices with the portability and sensitivity necessary to detect substance-specific chemical signatures. This means there is currently no substitute for sniffer dogs. Here we describe an insect screening procedure showing that the western honeybee (Apis mellifera can sense volatiles associated with pure samples of heroin and cocaine. We developed a portable electroantennographic device for the on-site measurement of volatile perception by these insects, and found a positive correlation between honeybee antennal responses and the concentration of specific drugs in test samples. Furthermore, we tested the ability of honeybees to learn the scent of heroin and trained them to show a reliable behavioral response in the presence of a highly-diluted scent of pure heroin. Trained honeybees could therefore be used to complement or replace the role of sniffer dogs as part of an automated drug detection system. Insects are highly sensitive to volatile compounds and provide an untapped resource for the development of biosensors. Automated conditioning as presented in this study could be developed as a platform for the practical detection of illicit drugs using insect-based sensors.

  8. Acaricide, fungicide and drug interactions in honey bees (Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Reed M Johnson

    Full Text Available BACKGROUND: Chemical analysis shows that honey bees (Apis mellifera and hive products contain many pesticides derived from various sources. The most abundant pesticides are acaricides applied by beekeepers to control Varroa destructor. Beekeepers also apply antimicrobial drugs to control bacterial and microsporidial diseases. Fungicides may enter the hive when applied to nearby flowering crops. Acaricides, antimicrobial drugs and fungicides are not highly toxic to bees alone, but in combination there is potential for heightened toxicity due to interactive effects. METHODOLOGY/PRINCIPAL FINDINGS: Laboratory bioassays based on mortality rates in adult worker bees demonstrated interactive effects among acaricides, as well as between acaricides and antimicrobial drugs and between acaricides and fungicides. Toxicity of the acaricide tau-fluvalinate increased in combination with other acaricides and most other compounds tested (15 of 17 while amitraz toxicity was mostly unchanged (1 of 15. The sterol biosynthesis inhibiting (SBI fungicide prochloraz elevated the toxicity of the acaricides tau-fluvalinate, coumaphos and fenpyroximate, likely through inhibition of detoxicative cytochrome P450 monooxygenase activity. Four other SBI fungicides increased the toxicity of tau-fluvalinate in a dose-dependent manner, although possible evidence of P450 induction was observed at the lowest fungicide doses. Non-transitive interactions between some acaricides were observed. Sublethal amitraz pre-treatment increased the toxicity of the three P450-detoxified acaricides, but amitraz toxicity was not changed by sublethal treatment with the same three acaricides. A two-fold change in the toxicity of tau-fluvalinate was observed between years, suggesting a possible change in the genetic composition of the bees tested. CONCLUSIONS/SIGNIFICANCE: Interactions with acaricides in honey bees are similar to drug interactions in other animals in that P450-mediated detoxication

  9. Neutralization of Apis mellifera bee venom activities by suramin.

    Science.gov (United States)

    El-Kik, Camila Z; Fernandes, Fabrício F A; Tomaz, Marcelo Amorim; Gaban, Glauco A; Fonseca, Tatiane F; Calil-Elias, Sabrina; Oliveira, Suellen D S; Silva, Claudia L M; Martinez, Ana Maria Blanco; Melo, Paulo A

    2013-06-01

    In this work we evaluated the ability of suramin, a polysulfonated naphthylurea derivative, to antagonize the cytotoxic and enzymatic effects of the crude venom of Apis mellifera. Suramin was efficient to decrease the lethality in a dose-dependent way. The hemoconcentration caused by lethal dose injection of bee venom was abolished by suramin (30 μg/g). The edematogenic activity of the venom (0.3 μg/g) was antagonized by suramin (10 μg/g) in all treatment protocols. The changes in the vascular permeability caused by A. mellifera (1 μg/g) venom were inhibited by suramin (30 μg/g) in the pre- and posttreatment as well as when the venom was preincubated with suramin. In addition, suramin also inhibited cultured endothelial cell lesion, as well as in vitro myotoxicity, evaluated in mouse extensor digitorum longus muscle, which was inhibited by suramin (10 and 25 μM), decreasing the rate of CK release, showing that suramin protected the sarcolemma against damage induced by components of bee venom (2.5 μg/mL). Moreover, suramin inhibited the in vivo myotoxicity induced by i.m. injection of A. mellifera venom in mice (0.5 μg/g). The analysis of the area under the plasma CK vs. time curve showed that preincubation, pre- and posttreatment with suramin (30 μg/g) inhibited bee venom myotoxic activity in mice by about 89%, 45% and 40%, respectively. Suramin markedly inhibited the PLA2 activity in a concentration-dependent way (1-30 μM). Being suramin a polyanion molecule, the effects observed may be due to the interaction of its charges with the polycation components present in A. mellifera bee venom.

  10. DINÂMICA DOS ATRIBUTOS FÍSICO-QUÍMICOS E VARIAÇÃO SAZONAL DOS ESTOQUES DE CARBONO NO SOLO EM DIFERENTES FITOFISIONOMIAS DO PANTANAL NORTE MATO-GROSSENSE

    Directory of Open Access Journals (Sweden)

    Juliana Milesi Mello

    2015-04-01

    Full Text Available O bioma Pantanal pode ser considerado um ambiente de hipersazonalidade, onde há um período de inundação pronunciada seguido por extenso período seco com temperaturas muito elevadas. A diversidade de suas fitofisionomias ocasiona aportes de carbono para o solo em quantidade e qualidade distintas. Com esse foco, este trabalho teve por objetivo verificar o efeito do ciclo hidrológico do Pantanal (enchente, cheia, vazante e estiagem sobre a dinâmica do estoque carbono orgânico do solo nas fitofisionomias de Cambarazal, de Floresta Ripária, de Cordilheira e de Espinheiral. Verificou-se que as fitofisionomias puderam ser separadas pela análise de componentes principais (ACP em três grupos distintos, caracterizados pela reserva de nutrientes e pela acidez do solo. O estoque de carbono do solo está condicionado por fatores sazonais e igualmente dependentes da fitofisionomia local que ocorreram nas fitofisionomias que apresentaram maior nível de fertilidade natural, ou seja, respectivamente o Cambarazal e o Espinheiral. O maior teor de carbono foi observado no período de enchente, na maioria das fitofisionomias, e o menor estoque de carbono aconteceu no período de vazante (2008, após o período de anaerobiose em razão da enchente e antes que o período seco passasse a ser determinante.

  11. ESTUDIO DE LA RESISTENCIA MECÁNICA DE MATERIALES COMPUESTOS POLIMÉRICOS REFORZADOS CON FIBRAS DE CARBONO

    Directory of Open Access Journals (Sweden)

    Enrique Rocha-Rangel

    2011-01-01

    Full Text Available Materiales compuestos hechos de una resina epóxica reforzada con diferentes contenidos de fibra de carbono, fueron preparados por dos técnicas de laminación diferentes. Se aplicó 1 Kg/cm2 de presión en los laminados, mientras, que otros laminados se sometieron a un vacío de 1 atm. De los resultados se tiene que las resistencias a la flexión y tensión de los compósitos son mejoradas con el aumento en el contenido de fibra en los mismos. Los compósitos resultantes presentan un mejor comportamiento mecánico bajo esfuerzos de tensión que cuando lo hacen bajo esfuerzos de flexión, debido a que en flexión las fibras se rompen eventualmente, provocando que el material falle a bajos valores de esfuerzo. Cuando los materiales compuestos son sometidos a tensión, las fibras trasmiten los esfuerzos entre ellas y el material falla hasta que se acumula la energía necesaria para romper todas las fibras de una sola vez.

  12. EXTRACCIÓN DE PLAGUICIDAS EN SUELO EMPLEANDO DIÓXIDO DE CARBONO SUPERCRÍTICO-COSOLVENTES

    Directory of Open Access Journals (Sweden)

    Jose Forero

    2010-04-01

    Full Text Available En este estudio se evaluó la eficiencia de tres solventes orgánicos (acetato de etilo, metanol y acetona empleados como cosolventes en la extracción con fluidos supercríticos (EFS de una mezcla de plaguicidas con diferentes características fisicoquímicas. Los análisis se realizaron por medio de cromatografía de gases con detección simultánea por microcaptura electrónica (_ECD y nitrógeno-fósforo (NPD acoplados en paralelo. Se hicieron extracciones a muestras de suelo fortificadas con los plaguicidas empleando dióxido de carbono supercrítico (CO2SC como fase extractante a 35 ºC y 14 MPa adicionando 10 mL de cada cosolvente. Se encontró que el metanol ofrece la mayor eficiencia en el proceso de extracción obteniendo valores de recuperación entre 51,24 y 123,50%.

  13. An Effective Method for Protecting Native API Hook Attacks in User-mode

    Directory of Open Access Journals (Sweden)

    K. Muthumanickam

    2015-01-01

    Full Text Available Today, many modern malware developers is taking the advantage of Application Programming Interface (API hook technique to take the control of the victim computer which making it difficult to detect their presence. Because of the sophistication of rootkit tools, a remote attacker can use native API to compromise any computer which can later be used for many illegal activities such as sniffing network lines, capturing passwords, sending spam and DDoS attack, etc. Thus to protect end-system by identifying and preventing native API malicious code hooking is a challenging problem to the defenders. Today, many different malware-analysis tools incur specific features against malwares but manual and error-prone. In this study, we proposed a behavior-based monitoring detection system to effectively deal native API hooks in user-mode. Unlike other malware identification techniques, our approach involved dynamically analyzing the behavior of native API call hooking malwares. Comparing our experimental evaluation results with existing tools show better performance with no false positive.

  14. Produtos naturais no comportamento defensivo de Apis mellifera L. = Natural products in the defensive behaviour of Apis mellifera L.

    Directory of Open Access Journals (Sweden)

    Renata Leonardo Lomele

    2010-07-01

    Full Text Available Os objetivos do estudo foram investigar a influência de produtos naturais como capim-limão (Cymbopogon citratus, folhas de abacateiro (Persea americana, casca de café (Coffea arabica e sementes de mamona (Ricinus communis na defensividade de Apis mellifera, e avaliar o efeito destes produtos no desenvolvimento populacional da colmeia. O comportamento defensivo foi avaliado por meio do tempo da primeira ferroada (TPF, número de ferrões (NFB e, o desenvolvimento populacional, pela área de cria aberta e fechada. Observou-se que o tratamento fumaça + sete sementes de mamona apresentou aumento significativo no TPF, em relação ao tratamento sem e com fumaça de maravalha. Com relação ao NFB, verificou-se que os tratamentos fumaça de maravalha + sete sementes de mamona e fumaça de maravalha + 20% de folhas de café foram diferentes do tratamento sem e com fumaça. Os demais tratamentos não diferiram significativamente em relação ao uso da fumaça ou sua ausência. A casca de café e a semente de mamona nãointerferiram no desenvolvimento populacional, sugerindo que estes compostos não foram tóxicos. Pode-se concluir que o uso de sementes de mamona e casca de café na fumaça pode representar importante ferramenta para a redução da defensividade, sem promover toxicidade para A. mellifera.The goal was to investigate the influence of natural products such as lemongrass (Cymbopogon citratus, dried avocado leaves (Persea americana, coffee husk (Coffea arabica and castor bean (Ricinus communis in the defense of Apis mellifera, as well the effect of these products on the population development of the beehive. Defensive behavior was evaluated by time of first sting (TFS and number of stingers (NS, and population development, by open brood area and operculated brood. It was observed that the treatment with smoke + seven castor beans presented significant increase in the TFS, for treatment without and with smoke. Regarding NS, it was verified

  15. [New Approach to the Mitotype Classification in Black Honeybee Apis mellifera mellifera and Iberian Honeybee Apis mellifera iberiensis].

    Science.gov (United States)

    Ilyasov, R A; Poskryakov, A V; Petukhov, A V; Nikolenko, A G

    2016-03-01

    The black honeybee Apis mellifera mellifera L. is today the only subspecies of honeybee which is suitable for commercial breeding in the climatic conditions of Northern Europe with long cold winters. The main problem of the black honeybee in Russia and European countries is the preservation of the indigenous gene pool purity, which is lost as a result of hybridization with subspecies, A. m. caucasica, A. m. carnica, A. m. carpatica, and A. m. armeniaca, introduced from southern regions. Genetic identification of the subspecies will reduce the extent of hybridization and provide the gene pool conservation of the black honeybee. Modern classification of the honeybee mitotypes is mainly based on the combined use ofthe DraI restriction endonuclease recognition site polymorphism and sequence polymorphism of the mtDNA COI-COII region. We performed a comparative analysis of the mtDNA COI-COII region sequence polymorphism in the honeybees ofthe evolutionary lineage M from Ural and West European populations of black honeybee A. m. mellifera and Spanish bee A. m. iberiensis. A new approach to the classification of the honeybee M mitotypes was suggested. Using this approach and on the basis of the seven most informative SNPs of the mtDNA COI-COII region, eight honeybee mitotype groups were identified. In addition, it is suggested that this approach will simplify the previously proposed complicated mitotype classification and will make it possible to assess the level of the mitotype diversity and to identify the mitotypes that are the most valuable for the honeybee breeding and rearing.

  16. API SPEC 5L会标认证审核企业需做的主要准备工作%The Main Preparatory Work for Enterprise API SPEC 5L Monogram Certification

    Institute of Scientific and Technical Information of China (English)

    方晓东

    2009-01-01

    随着TSG Z0004标准实施和API SPEC 5L以及API SPEC Q1标准的换版,当前申请API SPEC 5L会标使用许可证的企业应及时做好各项准备工作,接受审核组的审核.审核前需做的准备工作主要包括:①及时与审核员充分沟通;②各种审核文件的整理和完善;③维护和保养生产现场设备,完善各岗位现场作业指导文件,确保现场各种记录完整清楚.%Along TSG Z0004 standard implement and renewal edition of API SPEC 5L and API SPEC Q1,enterprises should make all preparations for applying API SPEC 5L monogram use permit right to receive auditor check.The main preparatory work include:①to completely communicate with auditor in time;②to file and improve all kinds of documents which will be checked;③to maintain equipments in production site,improve each job-site guidance document,and insure all kinds of records integrity and clarity. Key words:certification audit;API SPEC 5L;API SPEC Q1;monogram use permit

  17. A Comparison of Article Search APIs via Blinded Experiment and Developer Review

    Directory of Open Access Journals (Sweden)

    Jonathan Rochkind

    2013-01-01

    Full Text Available This study looks at perceived user preference between products that can provide a scholarly article search service via an application programming interface (API. The study set up a blinded review and asked users at Johns Hopkins to select the service that provided the most useful results. Few statistically significant preferences were detected, and some interpretation is provided of what the results might tell us. The specific products evaluated for this study are: Serials Solutions Summon, Ex Libris Primo, EBSCO EDS, EBSCOHost ‘traditional’ API, and Elsevier Scopus. Re-usable open source tools for implementing article search were created to support the study and future development, and a developer review of the APIs is included based on the developer's experience in this implementation.

  18. Studi Eksperimen Distribusi Temperatur Nyala Api Kompor Bioetanol Tipe Side Burner dengan Variasi Diameter Firewall

    Directory of Open Access Journals (Sweden)

    R.R. Vienna Sona Saputri Soetadi

    2012-09-01

    Full Text Available Untuk mendapatkan kompor bioetanol efisiensi thermal maksimal diperlukan penelitian komprehensif. Salah satunya adalah penelitian terhadap posisi peletakkan beban pada kompor bioetanol kompak. Pengujian dilakukan pada kompor uji bioetanol dengan kadar 99%, yaitu kompor bioetanol tipe side burner dengan firewall 2.5 inci dan firewall 3 inci. Pengukuran temperatur api dengan 13 thermocouple K dengan pengukuran searah api keatas setiap 5 mm-an. Kemudian, water boiling test dilakukan untuk mendapatkan daya dan beban dan dilanjutkan mengukur waktu pendidihan air. Hasil penelitian ini menunjukkan gambaran total distribusi temperatur nyala api difusi. Hasil menunjukkan untuk kompor 2.5 inci dengan daya 1.6 kW mempunyai temperatur 542 ºC dengan jarak ketinggian 5 mm dari rim kompor sedangkan kompor 3 inci menghasilkan daya 2.38 kW dengan temperatur 516 ºC.

  19. API2-MALT1 oncoprotein promotes lymphomagenesis via unique program of substrate ubiquitination and proteolysis.

    Science.gov (United States)

    Rosebeck, Shaun; Lim, Megan S; Elenitoba-Johnson, Kojo S J; McAllister-Lucas, Linda M; Lucas, Peter C

    2016-02-26

    Lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is the most common extranodal B cell tumor and accounts for 8% of non-Hodgkin's lymphomas. Gastric MALT lymphoma is the best-studied example and is a prototypical neoplasm that occurs in the setting of chronic inflammation brought on by persistent infection or autoimmune disease. Cytogenetic abnormalities are commonly acquired during the course of disease and the most common is chromosomal translocation t(11;18)(q21;q21), which creates the API2-MALT1 fusion oncoprotein. t(11;18)-positive lymphomas can be clinically aggressive and have a higher rate of dissemination than t(11;18)-negative tumors. Many cancers, including MALT lymphomas, characteristically exhibit deregulated over-activation of cellular survival pathways, such as the nuclear factor-κB (NF-κB) pathway. Molecular characterization of API2-MALT1 has revealed it to be a potent activator of NF-κB, which is required for API2-MALT1-induced cellular transformation, however the mechanisms by which API2-MALT1 exerts these effects are only recently becoming apparent. The API2 moiety of the fusion binds tumor necrosis factor (TNF) receptor associated factor (TRAF) 2 and receptor interacting protein 1 (RIP1), two proteins essential for TNF receptor-induced NF-κB activation. By effectively mimicking ligand-bound TNF receptor, API2-MALT1 promotes TRAF2-dependent ubiquitination of RIP1, which then acts as a scaffold for nucleating and activating the canonical NF-κB machinery. Activation occurs, in part, through MALT1 moiety-dependent recruitment of TRAF6, which can directly modify NF-κB essential modulator, the principal downstream regulator of NF-κB. While the intrinsic MALT1 protease catalytic activity is dispensable for this canonical NF-κB signaling, it is critical for non-canonical NF-κB activation. In this regard, API2-MALT1 recognizes NF-κB inducing kinase (NIK), the essential upstream regulator of non-canonical NF-κB, and cleaves it to

  20. The SEMAINE API: Towards a Standards-Based Framework for Building Emotion-Oriented Systems

    Directory of Open Access Journals (Sweden)

    Marc Schröder

    2010-01-01

    Full Text Available This paper presents the SEMAINE API, an open source framework for building emotion-oriented systems. By encouraging and simplifying the use of standard representation formats, the framework aims to contribute to interoperability and reuse of system components in the research community. By providing a Java and C++ wrapper around a message-oriented middleware, the API makes it easy to integrate components running on different operating systems and written in different programming languages. The SEMAINE system 1.0 is presented as an example of a full-scale system built on top of the SEMAINE API. Three small example systems are described in detail to illustrate how integration between existing and new components is realised with minimal effort.

  1. Using the RxNorm web services API for quality assurance purposes.

    Science.gov (United States)

    Peters, Lee; Bodenreider, Olivier

    2008-11-06

    Auditing large, rapidly evolving terminological systems is still a challenge. In the case of RxNorm, a standardized nomenclature for clinical drugs, we argue that quality assurance processes can benefit from the recently released application programming interface (API) provided by RxNav. We demonstrate the usefulness of the API by performing a systematic comparison of alternative paths in the RxNorm graph, over several thousands of drug entities. This study revealed potential errors in RxNorm, currently under review. The results also prompted us to modify the implementation of RxNav to navigate the RxNorm graph more accurately. The RxNav web services API used in this experiment is robust and fast.

  2. An API for Integrating Spatial Context Models with Spatial Reasoning Algorithms

    DEFF Research Database (Denmark)

    Kjærgaard, Mikkel Baun

    2006-01-01

    The integration of context-aware applications with spatial context models is often done using a common query language. However, algorithms that estimate and reason about spatial context information can benefit from a tighter integration. An object-oriented API makes such integration possible and ...... modeling. The utility of the API is evaluated in several real-world cases from an indoor location system, and spans several types of spatial reasoning algorithms.......The integration of context-aware applications with spatial context models is often done using a common query language. However, algorithms that estimate and reason about spatial context information can benefit from a tighter integration. An object-oriented API makes such integration possible...

  3. APIS : a value-added database of HST UV planetary auroral observations acquired since 1997

    Science.gov (United States)

    Lamy, L.; Henry, F.; Prangé, R.; Le Sidaner, P.

    2014-04-01

    The APIS service http://lesia.obspm.fr/apis/ (Auroral Planetary Imaging and Spectroscopy), aimed at facilitating the use of planetary auroral observations, was presented at EPSC last year, following its opening to the community in July 2013. This facility consists of : - a high level database derived from public Far-UV observations of Jupiter, Io, Ganymede, Saturn, Titan and Uranus acquired by the Hubble Space Telescope since 1997 (36 observational campaigns so far) ; - a specific search interface (Figure 1), aimed at browsing the database freely, quickly and efficiently through relevant search criteria (as planetary longitudes, moon or spacecraft ephemeris etc.). - Virtual-Observatory tools which enable the user to interactively work with images and spectra online. We will present the updated capabilities of APIS and illustrate them with several examples. Several tutorials are also directly available online.

  4. API2-MALT1 oncoprotein promotes lymphomagenesis via unique program of substrate ubiquitination and proteolysis

    Institute of Scientific and Technical Information of China (English)

    Shaun Rosebeck; Megan S Lim; Kojo SJ Elenitoba-Johnson; Linda MMcAllister-Lucas; Peter C Lucas

    2016-01-01

    Lymphoma of mucosa-associated lymphoid tissue(MALT lymphoma) is the most common extranodal B cell tumor and accounts for 8% of non-Hodgkin’s lymphomas. Gastric MALT lymphoma is the best-studied example and is a prototypical neoplasm that occurs in the setting of chronic inflammation brought on by persistent infection or autoimmune disease. Cytogenetic abnormalities are commonly acquired during the course of disease and the most common is chromosomal translocation t(11;18)(q21;q21), which creates the API2-MALT1 fusion oncoprotein. t(11;18)-positive lymphomas can be clinically aggressive and have a higher rate of dissemination than t(11;18)-negative tumors. Many cancers, including MALT lymphomas, characteristically exhibit deregulated over-activation of cellular survival pathways, such as the nuclear factor-κB(NF-κB) pathway. Molecular characterization of API2-MALT1 has revealed it to be a potent activator of NF-κB, which is required for API2-MALT1-induced cellular transformation, however the mechanisms by which API2-MALT1 exerts these effects are only recently becoming apparent. The API2 moiety of the fusion binds tumor necrosis factor(TNF) receptor associated factor(TRAF) 2 and receptor interacting protein 1(RIP1), two proteins essential for TNF receptor induced NF-κB activation. By effectively mimicking ligand-bound TNF receptor, API2-MALT1 promotes TRAF2-dependent ubiquitination of RIP1, which then acts as a scaffold for nucleating and activating the canonical NF-κB machinery. Activation occurs, in part, through MALT1 moiety-dependent recruitment of TRAF6, which can directly modify NF-κB essential modulator, the principal downstream regulator of NF-κB. While theintrinsic MALT1 protease catalytic activity is dispensable for this canonical NF-κB signaling, it is critical for noncanonical NF-κB activation. In this regard, API2-MALT1 recognizes NF-κB inducing kinase(NIK), the essential upstream regulator of non-canonical NF-κB, and cleaves it to generate

  5. MicroRNA-1 promotes apoptosis of hepatocarcinoma cells by targeting apoptosis inhibitor-5 (API-5).

    Science.gov (United States)

    Li, Dong; Liu, Yu; Li, Hua; Peng, Jing-Jing; Tan, Yan; Zou, Qiang; Song, Xiao-Feng; Du, Min; Yang, Zheng-Hui; Tan, Yong; Zhou, Jin-Jun; Xu, Tao; Fu, Zeng-Qiang; Feng, Jian-Qiong; Cheng, Peng; chen, Tao; Wei, Dong; Su, Xiao-Mei; Liu, Huan-Yi; Qi, Zhong-Chun; Tang, Li-Jun; Wang, Tao; Guo, Xin; Hu, Yong-He; Zhang, Tao

    2015-01-02

    Although microRNA-1 (miR-1) is a known liver cancer suppressor, the role of miR-1 in apoptosis of hepatoma cells has remained largely unknown. Our study shows that ectopic miR-1 overexpression induced apoptosis of liver hepatocellular carcinoma (HepG2) cells. Apoptosis inhibitor 5 (API-5) was found to be a potential regulator of miR-1 induced apoptosis, using a bioinformatics approach. Furthermore, an inverse relationship between miR-1 and API-5 expression was observed in human liver cancer tissues and adjacent normal liver tissues. Negative regulation of API-5 expression by miR-1 was demonstrated to promote apoptosis of HepG2 cells. Our study provides a novel regulatory mechanism of miR-1 in the apoptosis of hepatoma cells.

  6. The Design and Implementation of Cryptographic API%加密API的设计与实现

    Institute of Scientific and Technical Information of China (English)

    王军

    2004-01-01

    文章设计了一种简单易用、可扩展和可移植的加密API,简称SEPC-API.SEPC-API采用标准的C/C++来编写,并使用抽象密钥类分层结构来构造.文中详细描述了SEPC-API的设计和实现,并给出了应用示例.此外,SEPC-API中的多数函数设计遵循微软Crypto API的语法,这意味着微软Crypto API用户只需修改很少的代码就可以移植到SEPC-API.

  7. Estudo e comparação de materiais eletrocatalíticos de Pd e PdBi suportados em carbono e nanotubos de carbono para posterior uso em uma célula a combustível alcalina alimentada diretamente por etanol

    OpenAIRE

    2015-01-01

    Orientador: Prof. Dr. Mauro Coelho dos Santos Dissertação (mestrado) - Universidade Federal do ABC. Programa de Pós-Graduação em Ciência e Tecnologia/Química, 2015. A reação de oxidação eletroquímica do etanol foi estudada em meio alcalino utilizando-se os eletrocatalisadores Pd e PdBi (razões atômicas 90:10, 50:50 e 70:30 em 20% de metais) suportados em carbono e nanotubos de carbono. As formulações propostas foram preparadas pelo método de redução por borohidreto de sódio. Os eletroca...

  8. AN OVERVIEW OF THE UNCERTAINTY ANALYSIS, SENSITIVITY ANALYSIS, AND PARAMETER ESTIMATION (UA/SA/PE) API AND HOW TO IMPLEMENT IT

    Science.gov (United States)

    The Application Programming Interface (API) for Uncertainty Analysis, Sensitivity Analysis, andParameter Estimation (UA/SA/PE API) (also known as Calibration, Optimization and Sensitivity and Uncertainty (CUSO)) was developed in a joint effort between several members of both ...

  9. An overview of the CellML API and its implementation

    Directory of Open Access Journals (Sweden)

    Halstead Matt

    2010-04-01

    Full Text Available Abstract Background CellML is an XML based language for representing mathematical models, in a machine-independent form which is suitable for their exchange between different authors, and for archival in a model repository. Allowing for the exchange and archival of models in a computer readable form is a key strategic goal in bioinformatics, because of the associated improvements in scientific record accuracy, the faster iterative process of scientific development, and the ability to combine models into large integrative models. However, for CellML models to be useful, tools which can process them correctly are needed. Due to some of the more complex features present in CellML models, such as imports, developing code ab initio to correctly process models can be an onerous task. For this reason, there is a clear and pressing need for an application programming interface (API, and a good implementation of that API, upon which tools can base their support for CellML. Results We developed an API which allows the information in CellML models to be retrieved and/or modified. We also developed a series of optional extension APIs, for tasks such as simplifying the handling of connections between variables, dealing with physical units, validating models, and translating models into different procedural languages. We have also provided a Free/Open Source implementation of this application programming interface, optimised to achieve good performance. Conclusions Tools have been developed using the API which are mature enough for widespread use. The API has the potential to accelerate the development of additional tools capable of processing CellML, and ultimately lead to an increased level of sharing of mathematical model descriptions.

  10. Carbono, matéria orgânica leve e frações oxidáveis do carbono orgânico sob sistemas de aléias

    Directory of Open Access Journals (Sweden)

    Roni Fernandes Guareschi

    2013-06-01

    Full Text Available O objetivo deste estudo foi avaliar os teores de carbono orgânico (COT do solo, matéria orgânica leve (MOL em água e as frações oxidáveis do COT em uma área de cultivo de milho em aléias de Flemingia macrophylla submetida a diferentes manejos de sua parte aérea. A área de estudo está localizada na “Fazendinha Agroecológica”, no município de Seropédica, Rio de Janeiro, Brasil. O desenho experimental foi em blocos ao acaso, com 3 tratamentos e 8 repetições, consistindo dos seguintes tratamentos: testemunha (cultivo de milho com ausência de aléias; cultivo de milho em sistema de aléias com poda de 0,6 m de altura e cultivo de milho em sistema de aléias sem poda. Em cada uma das áreas foram coletadas amostras compostas nas profundidades de 0-5 cm. A presença de aléias, bem como, as podas realizadas em Flemingia macrophylla na área que essa encontrava-se associada ao cultivo de milho não alterou o teor de COT do solo. No entanto, a utilização dos caules e das folhas como adubo verde oriunda do tratamento onde se realizou a poda da parte aérea das aléias de Flemingia macrophylla, proporcionou ao solo aumento dos teores de MOL, Conteúdo de C da MOL e da fração F1.

  11. There-apy: The Use of Task, Imagery, and Symbolism To Connect the Inner and Outer Worlds.

    Science.gov (United States)

    Eisenstein-Naveh, A. Rosa

    2001-01-01

    Presents a model of therapy called there-apy, which weaves together the use of task, symbolism, and imagery into an ongoing process. Concrete tasks take on symbolic meaning, and symbolism gets actualized through achieving concrete tasks. There-apy connects the individual's outside and inside worlds and often involves the partner or family in the…

  12. Physicochemical characterisation and investigation of the bonding mechanisms of API-titanate nanotube composites as new drug carrier systems.

    Science.gov (United States)

    Sipos, Barbara; Pintye-Hódi, Klára; Kónya, Zoltán; Kelemen, András; Regdon, Géza; Sovány, Tamás

    2017-02-25

    Titanate nanotube (TNT) has recently been explored as a new carrier material for active pharmaceutical ingredients (API). The aim of the present work was to reveal the physicochemical properties of API-TNT composites, focusing on the interactions between the TNTs and the incorporated APIs. Drugs belonging to different Biopharmaceutical Classification System (BCS) classes were loaded into TNTs: diltiazem hydrochloride (BCS I.), diclofenac sodium (BCS II.), atenolol (BCS III.) and hydrochlorothiazide (BCS IV.). Experimental results demonstrated that it is feasible for spiral cross-sectioned titanate nanotubes to carry drugs and maintain their bioactivity. The structural properties of the composites were characterized by a range of analytical techniques, including FT-IR, DSC, TG-MS, etc. The interactions between APIs and TNTs were identified as electrostatic attractions, mainly dominated by hydrogen bonds. Based on the results, it can be stated that the strength of the association depends on the hydrogen donor strength of the API. The drug release of incorporated APIs was evaluated from compressed tablets and compared to that of pure APIs. Differences noticed in the dissolution profiles due to incorporation showed a correlation with the strength of interactions between the APIs and the TNTs observed in the above analytical studies.

  13. A geographical information system using the Google Map API for guidance to referral hospitals.

    Science.gov (United States)

    Kobayashi, Shinji; Fujioka, Tetsushi; Tanaka, Yuji; Inoue, Michiyoshi; Niho, Yoshiyuki; Miyoshi, Akira

    2010-12-01

    Our hospital acts as a regional core hospital through inter-hospital collaboration. Geographical information is necessary to guide patients to the other hospitals. Although paper maps, which contain directions, nearest public transportation, etc., are usually provided to guide patients to the hospitals, the geographical information tends to change daily. However, updating the geographical information on the maps is costly. We constructed an electronic geographical information system using the Google Map API ( http://code.google.com/apis/maps/ ) with open source software to improve our ability to collaborate with other clinics.

  14. Oriental orchid (Cymbidium pumilum) attracts drones of the Japanese honeybee (Apis cerana japonica) as pollinators.

    Science.gov (United States)

    Sasaki, M; Ono, M; Asada, S; Yoshida, T

    1991-12-01

    The discovery that drones of the Japanese honeybee (Apis cerana japonica) pollinate the oriental orchid (Cymbidium pumilum) is reported. Drones are attracted to the orchid flower aroma mainly during their mating flights in April through May. Some drones cluster on the flower racemes and others insert their heads deep into the flowers. Drones with pollinia on their scutellum visit other orchids, which facilitates pollination. Individual workers and swarming colonies are also strongly attracted by the flower aroma, but the allopatric western honeybee (Apis mellifera) is not attracted.

  15. When is it Biased? Assessing the Representativeness of Twitter's Streaming API

    OpenAIRE

    Morstatter, Fred; Pfeffer, Jürgen; Liu, Huan

    2014-01-01

    Twitter has captured the interest of the scientific community not only for its massive user base and content, but also for its openness in sharing its data. Twitter shares a free 1% sample of its tweets through the "Streaming API", a service that returns a sample of tweets according to a set of parameters set by the researcher. Recently, research has pointed to evidence of bias in the data returned through the Streaming API, raising concern in the integrity of this data service for use in res...

  16. Develop 3G Application with The J2ME SATSA API

    Science.gov (United States)

    JunWu, Xu; JunLing, Liang

    This paper describes research in the use of the Security and Trust Services API for J2ME (SATSA) to develop mobile applications. for 3G networks. SATSA defines a set of APIs that allows J2ME applications to communicate with and access functionality, secure storage and cryptographic operations provided by security elements such as smart cards and Wireless Identification Modules (WIM). A Java Card application could also work as an authentication module in a J2ME-based e-bank application. The e-bank application would allow its users to access their bank accounts using their cell phones.

  17. Heterosis en la longevidad de obreras Apis mielífera

    Directory of Open Access Journals (Sweden)

    Soares AE.

    2001-06-01

    Full Text Available Se estimó la media y la heterosis de la longevidad en obreras de abejas Apis mellifera. El expe-rimento fue desarrollado en el Apiario del Departamento de Genética de la Facultad de Medi-cina de la USP-Ribeirão Preto-Brasil y en Jaboticabal-SP, de 03/1997 a 05/1999. Seleccionamos 8 matrices inseminadas del apiário-USP (2africanizadas, 2italianas, 2cárnicasy 2italianas*cárnicos y 2 matrices (grupo-testigo de abejas Africanizadas-Silvestres.

  18. Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy

    DEFF Research Database (Denmark)

    Frick, Marcel; Fischer, Jörg; Helbling, Arthur;

    2016-01-01

    BACKGROUND: Component resolution recently identified distinct sensitization profiles in honey bee venom (HBV) allergy, some of which were dominated by specific IgE to Api m 3 and/or Api m 10, which have been reported to be underrepresented in therapeutic HBV preparations. OBJECTIVE: We performed...... a retrospective analysis of component-resolved sensitization profiles in HBV-allergic patients and association with treatment outcome. METHODS: HBV-allergic patients who had undergone controlled honey bee sting challenge after at least 6 months of HBV immunotherapy (n = 115) were included and classified...

  19. Atributos físicos e estoque de carbono do solo em áreas de Terra Preta Arqueológica da Amazônia

    Directory of Open Access Journals (Sweden)

    José Maurício da Cunha

    2017-03-01

    Full Text Available Para se avaliar a qualidade do solo e a sustentabilidade em ambientes de Terra Preta Arqueológica da Amazônia, é importante a caracterização dos impactos de uso de solo dos diferentes tipos de cobertura. Sendo assim, o objetivo deste trabalho foi avaliar os atributos físicos e o carbono orgânico em áreas de Terra Preta Arqueológica, no município de Novo Aripuanã, AM, sob os cultivos feijão guandu (Cajanus cajan e pastagem, em comparação com a cobertura de floresta, com base em técnicas de estatística tradicional univariada e multivariada e de geoestatística. Para isso foram delimitadas malhas com espaçamentos regulares e 88 pontos amostrais georreferenciados por malha. Foram coletadas amostras em blocos de solo com estrutura preservada e anéis volumétricos, para a determinação das propriedades físicas e do carbono orgânico do solo. O feijão guandu e pastagem diferem estatisticamente da floresta, que apresentaram características de estabilidade dos agregados acima da média, mas características texturais e carbono orgânico abaixo da média. O modelo exponencial, pelo semivariograma escalonado, mostrou que atributos físicos do solo apresentaram predominância, com grau de dependência de forte a moderado, sendo a área sob feijão guandu com maior variabilidade dos atributos do solo.

  20. Gestión Ambiental empresarial: cálculo de la huella de carbono en la industria vitivinícola.

    Directory of Open Access Journals (Sweden)

    Rosa Ana Rodriguez

    2014-12-01

    Full Text Available La huella de carbono es un indicador ambiental que busca cuantificar la cantidad de emisiones de gases de efecto invernadero (GHG. Su medición se convierte en una herramienta que permite trabajar bajo el concepto de eco-eficiencia e identificar oportunidades de reducción de consumo energético, ya que este último es la principal fuente de emisión de GHG a nivel mundial. El presente trabajo aplica la metodología PAS 2050:2011 para la medición de la huella de carbono, en la producción del vino blanco. La misma excluye las emisiones asociadas con los insumos humanos de energía, el transporte de los consumidores al punto de venta y el transporte provisto por animales. Sin embargo, se consideran todas las emisiones involucradas con el ciclo de vida del producto. Como producto principal de este trabajo, se obtuvo una planilla de cálculo que puede aplicarse al cálculo de huella de carbono de cualquier producción de vino blanco, independientemente de su tamaño y proceso. Se incluyó una estimación de la emisión de GHG, teniendo en cuenta todas las posibles variantes que pudiese tener el proceso en la región de Cuyo, definiéndose los límites de la empresa y operaciones a evaluar, desde la vendimia hasta la disposición final.

  1. The Assessment of DNA in Royal Jelly from Apis mellifera and Apis cerana by RAPD markers%中蜂与意蜂王浆中DNA的RAPD分析

    Institute of Scientific and Technical Information of China (English)

    邹阳; 黄康; 颜伟玉; 曾志将

    2007-01-01

    以中华蜜蜂(Apis cerana cerana)和意大利蜜蜂( Apis mellifera ligustica)王浆为材料,用改进的苯酚-氯仿法提取蜂王浆中的DNA,利用35个随机引物对提取出来的DNA进行RAPD扩增,结果表明:有6个随机引物能扩增出谱带,其中1个引物对所有王浆DNA样品的扩增结果完全相同,5个引物出现多态性.共检测到32条扩增谱带,其中24条为多态带.

  2. Variabilidad climática y la acumulación de carbono orgánico en el sector sur de la Corriente de California durante las etapas isotópicas marinas 1, 2 y 3

    OpenAIRE

    Alberto Sánchez; Carriquiry, José D.; B. Estela López-Ortiz

    2010-01-01

    La bomba biológica en el océano desempeña un papel muy importante en el ciclo de carbono global. Las tasas de enterramiento de carbono orgánico (Corg) al sur de los 40° de latitud norte en el Pacífico nororiental sugieren una mejor preservación de la productividad exportada durante el último periodo glaciar. La compilación de datos sobre la tasa de acumulación de Corg permitió extender el registro del Pacífico nororiental al sector sur de la Corriente de California, que corresponde al Pacífic...

  3. Estudo das propriedades elétricas do compósito de polianilina e nanotubos de carbono com palicação em transistores de efeito de campo

    OpenAIRE

    2013-01-01

    Resumo: Neste trabalho, é apresentado um estudo das propriedades elétricas e morfológicas de nanocompósitos de polianilina e nanotubos de carbono preenchidos com óxido de ferro ou ferro metálico, bem como a sua utilização na construção de dispositivos transistores de efeito de campo - FET (Field Effect Transistor). Desses estudos, pode-se verificar que o nanocompósito de polianilina com nanotubos de carbono apresenta um aumento de três ordens de grandeza na condutividade elétrica e de duas o...

  4. Integración del ciclo del carbono en el proceso de nutrición y bioquímica celular para alcanzar aprendizajes significativos en estudiantes del grado 11 de la Escuela Normal Superior De Ibagué

    OpenAIRE

    2012-01-01

    El presente trabajo pretende a través de estrategias pedagógicas de aula Iintegrar el ciclo del carbono en el proceso nutrición y la bioquímica celular para potenciar un aprendizaje significativo, desarrollar habilidades de pensamiento, y lograr una reflexión en torno a la protección del ambiente, y al auto-cuidado del cuerpo, se espera que los alumnos del grado undécimo de la Escuela Normal Superior de Ibagué tomen conciencia de la importancia del carbono en los carbohidratos, lípidos, prot...

  5. Equações para estimar o estoque de carbono no fuste de árvores individuais e em plantios comerciais de eucalipto Equations to estimate carbon stock in stems of individual trees ans stands of eucalyptus

    OpenAIRE

    Carlos Pedro Boechat Soares; Helio Garcia Leite; Eric Bastos Görgens

    2005-01-01

    O objetivo deste trabalho foi ajustar equações para estimar o carbono presente no fuste de árvores individuais de eucalipto e o estoque de carbono, por unidade de área, em diferentes condições de plantio. Para isso, foram utilizadas 532 árvores para ajustar a equação referente ao modelo alométrico de Schumacher e Hall (1933) e 95 parcelas permanentes para ajustar as equações referentes aos modelos de crescimento e produção, incluindo as seguintes variáveis independentes: idade (I), área basal...

  6. Efecto de plantaciones dendroenergéticas en el carbono a nivel de suelo, en dos suelos contrastantes de la región de Biobío, Chile

    OpenAIRE

    Edwin Esquivel; Rafael Rubilar; Simón Sandoval; Eduardo Acuña; Jorge Cancino; Miguel Espinosa; Fernando Muñoz

    2013-01-01

    La biomasa forestal como fuente de energía proveniente de plantaciones dendroenergéticas, al compararla con combustibles fósiles, presenta la ventaja de producir energía carbono-neutral, dado el secuestro de carbono (C) fijado en la biomasa producida y los aportes al suelo. Plantaciones forestales de corta rotación, altas densidades, y localizadas en terrenos marginales pueden representar una excelente oportunidad de producción de biomasa para la producción de energía o combustibles. Sin emba...

  7. Cirrose experimental induzida pela inalação de tetracloreto de carbono: adaptação da técnica e avaliação da peroxidação lipídica

    Directory of Open Access Journals (Sweden)

    CREMONESE Ricardo Viégas

    2001-01-01

    Full Text Available Racional - Administração a longo prazo de tetracloreto de carbono é modelo experimental para produzir fibrose hepática. O estresse oxidativo parece ser o mecanismo envolvido na hepatoxicidade por tetracloreto de carbono, onde as espécies ativas de oxigênio têm importante papel na patogênese da fibrose hepática. Objetivos - Avaliar a eficácia de um modelo experimental de cirrose hepática induzida pela inalação de tetracloreto de carbono em ratos, bem como avaliar a peroxidação lipídica e as características do líquido de ascite neste modelo. Material e Métodos - Inicialmente, acompanhou-se a evolução dos achados histológicos, através da técnica de hematoxilina e eosina, mediante o uso de tetracloreto de carbono inalatório ao longo das diferentes semanas (5ª, 7ª, 9ª, 12ª. Posteriormente, ao final da 15ª semana de estudo, os ratos, então divididos em três grupos (controle; controle + fenobarbital; e tetracloreto de carbono + fenobarbital, foram avaliados em sua histologia hepática, peroxidação lipídica e as características do líquido de ascite. Para as análises de peroxidação lipídica utilizaram-se as técnicas de substâncias reativas ao ácido tiobarbitúrico e de quimiluminescência. No líquido de ascite avaliaram-se a citologia e a bacteriologia. Resultados - Observou-se entre a 12ª e 15ª semanas de inalação o estabelecimento de cirrose em 100% dos animais submetidos a inalação com tetracloreto de carbono, acompanhada de um aumento significante na peroxidação lipídica no fígado dos ratos inalados com tetracloreto de carbono. Evidenciou-se a presença de infecção do líquido de ascite em um dos sete casos nos quais esta estava presente. Conclusão - O método inalatório desenvolvido é eficaz na indução de cirrose hepática e formação de ascite, sendo o estresse oxidativo um dos principais mecanismos da indução de cirrose pelo tetracloreto de carbono.

  8. Secuestro de carbono en la biomasa aérea de un sistema agrosilvopastoril de Cocos nucifera, Leucaena leucocephala Var. Cunningham y Pennisetum purpureum Cuba CT-115

    OpenAIRE

    J. M. Anguiano; Aguirre, J.; Palma, J.M. (José Manuel)

    2013-01-01

    Con el objetivo de estimar el secuestro de carbono en la biomasa aérea de un sistema agrosilvopastoril (sasp) compuesto por cocotero (Cocos nucifera), Leucaena leucocephala Var. Cunningham sembrada en alta densidad y Pennisetum purpureum Cuba CT-115, se llevó a cabo un estudio en un suelo con textura franco arcillo- arenosa. Se utilizó un diseño en bloques al azar con arreglo en parcelas divididas con cuatro tratamientos 0, 40, 60 y 80 mil árboles de leucaena ha-1 y tres repeticiones; la eval...

  9. SÍNTESIS DE NANOTUBOS DE CARBONO POR PIRÓLISIS DE ALFA-PINENO: MODELADO MATEMÁTICO Y VALIDACIÓN EXPERIMENTAL

    OpenAIRE

    López Tinoco, Julián

    2012-01-01

    El objetivo de este trabajo fue realizar y validar de manera experimental un modelo matemático para hacer más eficiente la producción de nanotubos de carbono (NTC). La síntesis de los NTC se llevó a cabo mediante el método de spray pirólisis variando los flujos del gas acarreador de 2.5 lpm a 7.5 lpm, manteniendo constante la concentración de catalizador y la temperatura de reacción. Los materiales obtenidos se caracterizaron mediante Análisis Termogravimetrico (TGA) y Micro...

  10. Diseño de un proceso de fabricación de un material compuesto de aluminio reforzado con fibra de carbono

    OpenAIRE

    De Robles Besné, Blanca; Morera Roca, Sara

    2013-01-01

    En el presente proyecto se diseña un proceso para la fabricación de un material compuesto con matriz de Al12Si y refuerzo de fibras de carbono de alto módulo. Se ha escogido el proceso de pulvimetalurgia ya que es uno de los menos investigados para estos materiales. El proceso de experimentación empieza con el mezclado de los materiales. La proporción se mantuvo en todo momento entre el 5% y el 10% en volumen de refuerzo. La medida de las fibras se fijó en 5 mm. Esta longitud se redujo a e...

  11. Cálculo de la Huella de Carbono en la Universidad Politécnica de Cartagena : en busca de la ecoeficiencia

    OpenAIRE

    Hermosilla Alcaraz, Arantzazu

    2015-01-01

    El presente Trabajo Fin de Máster se plantea como objetivo global el estudio de la problemática ambiental en la Universidad Politécnica de Cartagena (UPCT), a través de la herramienta de gestión ambiental conocida como Huella de Carbono, con el deseo de que sirva como referencia para estudios y campañas posteriores de sensibilización ambiental de nuestra comunidad universitaria. Para ello, se plantean los siguientes objetivos específicos: I. Dar a conocer las distintas herramientas que exi...

  12. Avaliação do ciclo de vida e estoque de carbono da produção de leite em Pastoreio Racional Voisin

    OpenAIRE

    Seó, Hizumi Lua Sarti

    2015-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Agroecossistemas, Florianópolis, 2015. Neste trabalho avaliou-se o desempenho ambiental do sistema de manejo Pastoreio Racional Voisin (PRV). Para tanto, estimou-se o estoque de carbono neste sistema e comparou-se ao sistema de plantio direto (SPD) de milho em sucessão com consórcio de azevém e aveia. Durante a produção de leite, ocorre a emissão de poluentes ao ambien...

  13. Modelo para calculo estimación del carbono en Tipo Forestal Roble-Raulí-Coigüe en la Reserva Nacional Malleco: Chile

    OpenAIRE

    Norman Moreno Garcia; Miguel Angel Herrera Machuca; Rinaldo Luiz Caraciolo Ferreira

    2011-01-01

    El objetivo de este trabajo es la selección de un modelo para estimación de carbono en Tipo Forestal Roble-Raulí y Coigüe. La recolección de datos se realizo en la Reserva Nacional Malleco. Cada sitio fue representado por un grupo de 5 parcelas (cuadradas, de lado 35m, superficie 1225m2), ubicadas en un transecto según la pendiente más fuerte. Fueron estimados los volúmenes de madera con y sin corteza de la totalidad de los individuos por medio de funciones para cada especie del tipo forestal...

  14. Decomposição de diferentes doses de palhada de cana-de-açúcar e seu efeito sobre o carbono do solo

    OpenAIRE

    José Geraldo de Abreu Sousa Junior

    2015-01-01

    O objetivo desta pesquisa foi avaliar a decomposição de diferentes quantidades iniciais de palhada de cana-de-açúcar depositadas sobre o solo, sob diferentes práticas de manejo e determinar o acúmulo de carbono orgânico total (COT) neste solo ao longo de três cortes da cana. Para tanto, foram instalados três ensaios em lavoura de cana-de-açúcar no município de Piracicaba. No experimento 1 foram depositadas na entrelinha da cultura, sobre o solo, diferentes quantidades de palhada (3,5; 7; 14 e...

  15. An example of how to handle amorphous fractions in API during early pharmaceutical development: SAR114137--a successful approach.

    Science.gov (United States)

    Petzoldt, Christine; Bley, Oliver; Byard, Stephen J; Andert, Doris; Baumgartner, Bruno; Nagel, Norbert; Tappertzhofen, Christoph; Feth, Martin Philipp

    2014-04-01

    The so-called pharmaceutical solid chain, which encompasses drug substance micronisation to the final tablet production, at pilot plant scale is presented as a case study for a novel, highly potent, pharmaceutical compound: SAR114137. Various solid-state analytical methods, such as solid-state Nuclear Magnetic Resonance (ssNMR), Differential Scanning Calorimetry (DSC), Dynamic Water Vapour Sorption Gravimetry (DWVSG), hot-stage Raman spectroscopy and X-ray Powder Diffraction (XRPD) were applied and evaluated to characterise and quantify amorphous content during the course of the physical treatment of crystalline active pharmaceutical ingredient (API). DSC was successfully used to monitor the changes in amorphous content during micronisation of the API, as well as during stability studies. (19)F solid-state NMR was found to be the method of choice for the detection and quantification of low levels of amorphous API, even in the final drug product (DP), since compaction during tablet manufacture was identified as a further source for the formation of amorphous API. The application of different jet milling techniques was a critical factor with respect to amorphous content formation. In the present case, the change from spiral jet milling to loop jet milling led to a decrease in amorphous API content from 20-30 w/w% to nearly 0 w/w% respectively. The use of loop jet milling also improved the processability of the API. Stability investigations on both the milled API and the DP showed a marked tendency for recrystallisation of the amorphous API content on exposure to elevated levels of relative humidity. No significant impact of amorphous API on either the chemical stability or the dissolution rate of the API in drug formulation was observed. Therefore, the presence of amorphous content in the oral formulation was of no consequence for the clinical trial phases I and II.

  16. Comportamiento mecánico de la aleación AZ31 reforzada con nanofibras de carbono

    Directory of Open Access Journals (Sweden)

    Adeva, P.

    2010-12-01

    Full Text Available The aim of this study is to investigate the effect of reinforcing AZ31 with carbon nanofibres. The materials AZ31, AZ31-1 % C y AZ31-2 % C were produced by a conventional powder metallurgy route consisting of mechanical mixing of nanofibres and powders of AZ31, cool compactation and extrusion at 350 °C. After extrusion the three materials exhibited a recrystallized microstructure of similar grain size, fine and rather inhomogeneous. Furthermore, they presented a weak fibre texture with basal plane parallel to the extrusion direction. The tensile properties were affected by the nanofibres presence only at 100 °C. At this temperature, yield strength and tensile strength were 30% higher than in the unreinforced alloy.

    En este trabajo se ha estudiado el efecto de la adición de nanofibras de carbono en las propiedades mecánicas de la aleación AZ31 procesada por una ruta pulvimetalúrgica convencional. Se prepararon tres materiales, AZ31, AZ31- 1 % C y AZ31-2 % C. Tras una mezcla mecánica de las nanofibras con los polvos de AZ31, se precompactaron en frío y se extruyeron a 350 °C. Los tres presentan una microestructura recristalizada con un tamaño de grano similar, fino aunque algo heterogéneo. Los tres materiales presentan una débil textura de fibra con el plano basal paralelo a la dirección de extrusión. Las propiedades mecánicas a tracción únicamente se ven afectadas por la presencia de nanofibras a 100 °C superando los materiales reforzados en un 30 % a los valores de límite elástico y resistencia de la aleación sin reforzar.

  17. Calidad del carbono orgánico del suelo en diferentes técnicas de manejo de residuos forestales

    Directory of Open Access Journals (Sweden)

    Ana Maria Lupi

    2012-06-01

    Full Text Available http://dx.doi.org/10.5902/198050985736Las distintas técnicas de cosecha y manejo de residuos pueden provocar cambios en la cantidad y calidad de la materia orgánica (MO del suelo. El objetivo de este trabajo fue evaluar las modificaciones en la concentración y la calidad de la MO en un Ultisol con diferentes manejos de los residuos de la cosecha forestal del Pinus elliottii Engelm, al inicio de la segunda rotación. Los tratamientos analizados fueron: a extracción manual de los residuos de la cosecha y del piso forestal, suelo descubierto (ER, b quema de residuos y del mantillo, y laboreo con rastra (PI, c conservación de residuos y del mantillo sobre el suelo (PC. Se determinó el carbono orgánico (CO en todo el suelo y en las fracciones de ácidos fúlvicos (AF, ácidos húmicos (AH, huminas (HU y en la fracción liviana (CL. La conservación de los residuos de la cosecha no aumentó el CO ni el CL. Se observó una pérdida de la fracción de ácidos fúlvicos (AF particularmente en PI. Los tratamientos sin residuos forestales (ER y PI muestran un aumento en el grado de estabilización de la MO con un incremento de las HU y de la relación CAH/CAF.

  18. Influência da relação estequiométrica resina/endurecedor em propriedades mecânicas de compósitos ternários hierárquicos resina - epóxi/tecido de fibra de carbono/nanotubos de carbono

    Directory of Open Access Journals (Sweden)

    Kássio André Lacerda

    2014-01-01

    Full Text Available A produção de materiais que apresentem alto desempenho em suas aplicações exige avanços tecnológicos e científicos. Os elevados valores de resistência à tração e módulo de elasticidade, aliados à flexibilidade, baixa densidade e alta razão de aspecto, fazem dos nanotubos de carbono excepcionais candidatos para reforçar compósitos poliméricos. Preparamos por laminação sistemas compósitos ternários à base de resina epóxi/tecidos de fibra de carbono (para os binários, acrescendo nanotubos de carbono para os sistemas ternários. Os parâmetros estequiométricos do sistema epoxídico (valor de Phr e concentração de nanotubos de carbono empregado nos sistemas compósitos tiveram avaliadas suas morfologias (MEV, propriedades térmicas (TG e mecânicas (ASTM D790. Embora o sistema epoxídico com Phr 10,0 tenha apresentado uma maior estabilidade térmica, os compósitos ternários produzidos a partir do sistema com Phr 26,6 mostraram valores de tensão máxima e módulo de elasticidade até 8 vezes maiores que aqueles produzidos com o sistema Phr 10. A adição de nanotubos de carbono aos compósitos com Phr 26,6 resultou em ganhos adicionais de aproximadamente 38 e 15% na tensão máxima e no módulo de elasticidade, respectivamente. Esses resultados revelaram a limitação nos métodos de integralização de nanoestruturas a sistemas compósitos, onde as dispersões estão limitadas a uma série de fatores inerentes a interação química e/ou física durante a fabricação dos compósitos nanoestruturados.

  19. Insights into social insects from the genome of the honeybee Apis mellifera

    DEFF Research Database (Denmark)

    Hauser, Frank; Cazzamali, Giuseppe; Williamson, Michael

    2006-01-01

    Here we report the genome sequence of the honeybee Apis mellifera, a key model for social behaviour and essential to global ecology through pollination. Compared with other sequenced insect genomes, the A. mellifera genome has high A+T and CpG contents, lacks major transposon families, evolves mo...

  20. Sperm use economy of honeybee (Apis mellifera) queens

    DEFF Research Database (Denmark)

    Baer, Boris; Collins, Jason; Maalaps, Kristiina;

    2016-01-01

    the fecundity and longevity of queens and therefore colony fitness. We quantified the number of sperm that honeybee (Apis mellifera) queens use to fertilize eggs. We examined sperm use in naturally mated queens of different ages and in queens artificially inseminated with different volumes of semen. We found...

  1. Synergistic effects of non-Apis bees and honey bees for pollination services.

    Science.gov (United States)

    Brittain, Claire; Williams, Neal; Kremen, Claire; Klein, Alexandra-Maria

    2013-03-07

    In diverse pollinator communities, interspecific interactions may modify the behaviour and increase the pollination effectiveness of individual species. Because agricultural production reliant on pollination is growing, improving pollination effectiveness could increase crop yield without any increase in agricultural intensity or area. In California almond, a crop highly dependent on honey bee pollination, we explored the foraging behaviour and pollination effectiveness of honey bees in orchards with simple (honey bee only) and diverse (non-Apis bees present) bee communities. In orchards with non-Apis bees, the foraging behaviour of honey bees changed and the pollination effectiveness of a single honey bee visit was greater than in orchards where non-Apis bees were absent. This change translated to a greater proportion of fruit set in these orchards. Our field experiments show that increased pollinator diversity can synergistically increase pollination service, through species interactions that alter the behaviour and resulting functional quality of a dominant pollinator species. These results of functional synergy between species were supported by an additional controlled cage experiment with Osmia lignaria and Apis mellifera. Our findings highlight a largely unexplored facilitative component of the benefit of biodiversity to ecosystem services, and represent a way to improve pollinator-dependent crop yields in a sustainable manner.

  2. Gas chromatography coupled to atmospheric pressure ionization mass spectrometry (GC-API-MS): review.

    Science.gov (United States)

    Li, Du-Xin; Gan, Lin; Bronja, Amela; Schmitz, Oliver J

    2015-09-03

    Although the coupling of GC/MS with atmospheric pressure ionization (API) has been reported in 1970s, the interest in coupling GC with atmospheric pressure ion source was expanded in the last decade. The demand of a "soft" ion source for preserving highly diagnostic molecular ion is desirable, as compared to the "hard" ionization technique such as electron ionization (EI) in traditional GC/MS, which fragments the molecule in an extensive way. These API sources include atmospheric pressure chemical ionization (APCI), atmospheric pressure photoionization (APPI), atmospheric pressure laser ionization (APLI), electrospray ionization (ESI) and low temperature plasma (LTP). This review discusses the advantages and drawbacks of this analytical platform. After an introduction in atmospheric pressure ionization the review gives an overview about the history and explains the mechanisms of various atmospheric pressure ionization techniques used in combination with GC such as APCI, APPI, APLI, ESI and LTP. Also new developments made in ion source geometry, ion source miniaturization and multipurpose ion source constructions are discussed and a comparison between GC-FID, GC-EI-MS and GC-API-MS shows the advantages and drawbacks of these techniques. The review ends with an overview of applications realized with GC-API-MS.

  3. Dispersibility of lactose fines as compared to API in dry powders for inhalation.

    Science.gov (United States)

    Thalberg, Kyrre; Åslund, Simon; Skogevall, Marcus; Andersson, Patrik

    2016-05-17

    This work investigates the dispersion performance of fine lactose particles as function of processing time, and compares it to the API, using Beclomethasone Dipropionate (BDP) as model API. The total load of fine particles is kept constant in the formulations while the proportions of API and lactose fines are varied. Fine particle assessment demonstrates that the lactose fines have higher dispersibility than the API. For standard formulations, processing time has a limited effect on the Fine Particle Fraction (FPF). For formulations containing magnesium stearate (MgSt), FPF of BDP is heavily influenced by processing time, with an initial increase, followed by a decrease at longer mixing times. An equation modeling the observed behavior is presented. Surprisingly, the dispersibility of the lactose fines present in the same formulation remains unaffected by mixing time. Magnesium analysis demonstrates that MgSt is transferred to the fine particles during the mixing process, thus lubrication both BDP and lactose fines, which leads to an increased FPF. Dry particle sizing of the formulations reveals a loss of fine particles at longer mixing times. Incorporation of fine particles into the carrier surfaces is believed to be behind this, and is hence a mechanism of importance as regards the dispersion performance of dry powders for inhalation.

  4. ApiNATOMY: a novel toolkit for visualizing multiscale anatomy schematics with phenotype-related information.

    Science.gov (United States)

    de Bono, Bernard; Grenon, Pierre; Sammut, Stephen John

    2012-05-01

    A significant proportion of biomedical resources carries information that cross references to anatomical structures across multiple scales. To improve the visualization of such resources in their anatomical context, we developed an automated methodology that produces anatomy schematics in a consistent manner,and provides for the overlay of anatomy-related resource information onto the same diagram. This methodology, called ApiNATOMY, draws upon the topology of ontology graphs to automatically lay out treemaps representing body parts as well as semantic metadata linking to such ontologies. More generally, ApiNATOMY treemaps provide an efficient and manageable way to visualize large biomedical ontologies in a meaningful and consistent manner. In the anatomy domain, such treemaps will allow epidemiologists, clinicians, and biomedical scientists to review, and interact with, anatomically aggregated heterogeneous data and model resources. Such an approach supports the visual identification of functional relations between anatomically colocalized resources that may not be immediately amenable to automation by ontology-based inferencing. We also describe the application of ApiNATOMY schematics to integrate, and add value to, human phenotype-related information—results are found at http://apinatomy.org. The long-term goal for the ApiNATOMY toolkit is to support clinical and scientific graphical user interfaces and dashboards for biomedical resource management and data analytics.

  5. Spatial and temporal variation of metal concentrations in adult honeybees (Apis mellifera L.)

    NARCIS (Netherlands)

    Steen, van der J.J.M.; Kraker, J.; Grotenhuis, J.T.C.

    2012-01-01

    Honeybees (Apis mellifera L.) have great potential for detecting and monitoring environmental pollution, given their wide-ranging foraging behaviour. Previous studies have demonstrated that concentrations of metals in adult honeybees were significantly higher at polluted than at control locations. T

  6. Testing of the structure of macromolecular polymer films containing solid active pharmaceutical ingredient (API) particles

    Energy Technology Data Exchange (ETDEWEB)

    Boelcskei, E. [Department of Pharmaceutical Technology, University of Szeged, H-6720 Szeged, Eoetvoes u. 6 (Hungary); Suevegh, K. [Laboratory of Nuclear Chemistry, Eoetvoes Lorand University, H-1518 Budapest 112, P.O. Box 32 (Hungary); Marek, T. [Hungarian Academy of Sciences, Research Group for Nuclear Techniques in Structural Chemistry, Eoetvoes Lorand University, H-1518 Budapest 112, P.O. Box 32 (Hungary); Regdon, G. [Department of Pharmaceutical Technology, University of Szeged, H-6720 Szeged, Eoetvoes u. 6 (Hungary); Pintye-Hodi, K., E-mail: klara.hodi@pharm.u-szeged.h [Department of Pharmaceutical Technology, University of Szeged, H-6720 Szeged, Eoetvoes u. 6 (Hungary)

    2011-07-15

    The aim of the present study was to investigate the structure of free films of Eudragit{sup L} 30D-55 containing different concentrations (0%, 1% or 5%) of diclofenac sodium by positron annihilation spectroscopy. The data revealed that the size of the free-volume holes and the lifetimes of ortho-positronium atoms decreased with increase of the API concentration. Films containing 5% of the API exhibited a different behavior during storage (17 {sup o}C, 65% relative humidity (RH)) in consequence of the uptake of water from the air. -- Highlights: {yields} The aim of the present study was to investigate the structure of free films of Eudragit{sup L} 30D-55 containing different concentrations (0%, 1% or 5%) of diclofenac sodium by positron annihilation spectroscopy. {yields} The data revealed that the size of the free-volume holes and the lifetimes of ortho-positronium atoms decreased with increase of the API concentration (). {yields} The API distorts the original polymer structure, but as time goes by, the metastable structure relaxes and it is almost totally restored after 3 weeks of storage (17 {sup o}C, 65% RH).

  7. ACME algorithms for contact in a multiphysics environment API version 2.2.

    Energy Technology Data Exchange (ETDEWEB)

    Heinstein, Martin Wilhelm; Glass, Micheal W.; Gullerud, Arne S.; Brown, Kevin H.; Voth, Thomas Eugene; Jones, Reese E.

    2004-07-01

    An effort is underway at Sandia National Laboratories to develop a library of algorithms to search for potential interactions between surfaces represented by analytic and discretized topological entities. This effort is also developing algorithms to determine forces due to these interactions for transient dynamics applications. This document describes the Application Programming Interface (API) for the ACME (Algorithms for Contact in a Multiphysics Environment) library.

  8. Reliability of the Advanced Psychodiagnostic Interpretation (API) Scoring System for the Bender Gestalt.

    Science.gov (United States)

    Aucone, Ernest J.; Raphael, Alan J.; Golden, Charles J.; Espe-Pfeifer, Patricia; Seldon, Jen; Pospisil, Tanya; Dornheim, Liane; Proctor-Weber, Zoe; Calabria, Michael

    1999-01-01

    Assessed the interrater reliability of the revised Advanced Psychodiagnostic Interpretation (API) (A. Raphael and C. Golden, 1998) scoring system for the Bender Gestalt Test (L. Bender, 1938). Agreement across nine raters exceeded 90% for each of three clinical protocols, and kappa statistics indicated good interrater reliability. (SLD)

  9. Identification of clinical yeasts by Vitek MS system compared with API ID 32 C.

    Science.gov (United States)

    Durán-Valle, M Teresa; Sanz-Rodríguez, Nuria; Muñoz-Paraíso, Carmen; Almagro-Moltó, María; Gómez-Garcés, José Luis

    2014-05-01

    We performed a clinical evaluation of the Vitek MS matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) system with the commercial database version 2.0 for rapid identification of medically important yeasts as compared with the conventional phenotypic method API ID 32 C. We tested 161 clinical isolates, nine isolates from culture collections and five reference strains. In case of discrepant results or no identification with one or both methods, molecular identification techniques were employed. Concordance between both methods was observed with 160/175 isolates (91.42%) and misidentifications by both systems occurred only when taxa were not included in the respective databases, i.e., one isolate of Candida etchellsii was identified as C. globosa by Vitek MS and two isolates of C. orthopsilosis were identified as C. parapsilosis by API ID 32 C. Vitek MS could not identify nine strains (5.14%) and API ID 32 C did not identify 13 (7.42%). Vitek MS was more reliable than API ID 32 C and reduced the time required for the identification of clinical isolates to only a few minutes.

  10. Continuous API-crystal coating via coacervation in a tubular reactor.

    Science.gov (United States)

    Besenhard, M O; Thurnberger, A; Hohl, R; Faulhammer, E; Rattenberger, J; Khinast, J G

    2014-11-20

    We present a proof-of-concept study of a continuous coating process of single API crystals in a tubular reactor using coacervation as a microencapsulation technique. Continuous API crystal coating can have several advantages, as in a single step (following crystallization) individual crystals can be prepared with a functional coating, either to change the release behavior, to protect the API from gastric juice or to modify the surface energetics of the API (i.e., to tailor the hydrophobic/hydrophilic characteristics, flowability or agglomeration tendency, etc.). The coating process was developed for the microencapsulation of a lipophilic core material (ibuprofen crystals of 20 μm- to 100 μm-size), with either hypromellose phthalate (HPMCP) or Eudragit L100-55. The core material was suspended in an aqueous solution containing one of these enteric polymers, fed into the tubing and mixed continuously with a sodium sulfate solution as an antisolvent to induce coacervation. A subsequent temperature treatment was applied to optimize the microencapsulation of crystals via the polymer-rich coacervate phase. Cross-linking of the coating shell was achieved by mixing the processed material with an acidic solution (pH<3). Flow rates, temperature profiles and polymer-to-antisolvent ratios had to be tightly controlled to avoid excessive aggregation, leading to pipe plugging. This work demonstrates the potential of a tubular reactor design for continuous coating applications and is the basis for future work, combining continuous crystallization and coating.

  11. Does Year Round Schooling Affect the Outcome and Growth of California's API Scores?

    Science.gov (United States)

    Wu, Amery D.; Stone, Jake E.

    2010-01-01

    This paper examined whether year round schooling (YRS) in California had an effect upon the outcome and growth of schools' Academic Performance Index (API) scores. While many previous studies had examined the connection between YRS and academic achievement, most had lacked the statistical rigour required to provide reliable interpretations. As a…

  12. An Auto-Configuration System for the GMSEC Architecture and API

    Science.gov (United States)

    Moholt, Joseph; Mayorga, Arturo

    2007-01-01

    A viewgraph presentation on an automated configuration concept for The Goddard Mission Services Evolution Center (GMSEC) architecture and Application Program Interface (API) is shown. The topics include: 1) The Goddard Mission Services Evolution Center (GMSEC); 2) Automated Configuration Concept; 3) Implementation Approach; and 4) Key Components and Benefits.

  13. Responses of Varroa-resistant honey bees (Apis mellifera L.) to Deformed wing virus

    Science.gov (United States)

    The negative impact of Deformedwing virus (DWV) on European honey bees Apis mellifera is magnified by Varroa destructor parasitism. This study compared the responses of two Varroa-resistant honey bee stocks, pure Russian honey bees (RHB) and out-crossed Varroa Sensitive Hygienic bees, Pol-line (POL)...

  14. Young and old honey bee (Apis mellifera) larvae differentially prime the developmental maturation of their caregivers

    Science.gov (United States)

    In eusocial insects daughters rear the offspring of the queen to adulthood. In the honey bee, Apis mellifera, nurses differentially regulate larval nutrition. Among worker-destined larvae, younger instars receive an unrestricted diet paralleling that of queen larvae in protein composition but with r...

  15. Involvement of Phosphorylated "Apis Mellifera" CREB in Gating a Honeybee's Behavioral Response to an External Stimulus

    Science.gov (United States)

    Gehring, Katrin B.; Heufelder, Karin; Feige, Janina; Bauer, Paul; Dyck, Yan; Ehrhardt, Lea; Kühnemund, Johannes; Bergmann, Anja; Göbel, Josefine; Isecke, Marlene; Eisenhardt, Dorothea

    2016-01-01

    The transcription factor cAMP-response element-binding protein (CREB) is involved in neuronal plasticity. Phosphorylation activates CREB and an increased level of phosphorylated CREB is regarded as an indicator of CREB-dependent transcriptional activation. In honeybees ("Apis mellifera") we recently demonstrated a particular high…

  16. Polymorphic DNA sequences of the fungal honey bee pathogen Ascosphaera apis

    DEFF Research Database (Denmark)

    Jensen, Annette B; Welker, Dennis L; Kryger, Per

    2012-01-01

    was then compared among the different loci, and three were found to have the greatest detection power for identifying A. apis haplotypes. The described loci can help to resolve strain differences and population genetic structures, to elucidate host–pathogen interaction and to test evolutionary hypotheses...

  17. Enabling Mobile Air Quality App Development with an AirNow API

    Science.gov (United States)

    Dye, T.; White, J. E.; Ludewig, S. A.; Dickerson, P.; Healy, A. N.; West, J. W.; Prince, L. A.

    2013-12-01

    The U.S. Environmental Protection Agency's (EPA) AirNow program works with over 130 participating state, local, and federal air quality agencies to obtain, quality control, and store real-time air quality observations and forecasts. From these data, the AirNow system generates thousands of maps and products each hour. Each day, information from AirNow is published online and in other media to assist the public in making health-based decisions related to air quality. However, an increasing number of people use mobile devices as their primary tool for obtaining information, and AirNow has responded to this trend by publishing an easy-to-use Web API that is useful for mobile app developers. This presentation will describe the various features of the AirNow application programming interface (API), including Representational State Transfer (REST)-type web services, file outputs, and RSS feeds. In addition, a web portal for the AirNow API will be shown, including documentation on use of the system, a query tool for configuring and running web services, and general information about the air quality data and forecasts available. Data published via the AirNow API includes corresponding Air Quality Index (AQI) levels for each pollutant. We will highlight examples of mobile apps that are using the AirNow API to provide location-based, real-time air quality information. Examples will include mobile apps developed for Minnesota ('Minnesota Air') and Washington, D.C. ('Clean Air Partners Air Quality'), and an app developed by EPA ('EPA AirNow').

  18. Huella de carbono en cinco establecimientos de salud del tercer nivel de atención de Perú, 2013

    Directory of Open Access Journals (Sweden)

    Celso Bambarén-Alatrista

    Full Text Available Se realizó un estudio para calcular la huella de carbono generada por los establecimientos de salud del tercer nivel de atención ubicados en la ciudad de Lima, Perú, en el año 2013. Se obtuvieron los reportes del consumo de recursos energéticos y agua, así como la generación de residuos de cinco establecimientos, los cuales contribuyeron al cambio climático con la emisión de 14 462 teq CO2. El 46% de estas emisiones están asociadas al consumo de combustible para el funcionamiento de la casa de fuerza, generadores eléctricos y vehículos de transporte. Un 44% se relacionan con el consumo de energía eléctrica, y el restante 10% con la utilización de agua y generación de residuos sólidos hospitalarios. CO2, N2O y CH4 son los gases de efecto invernadero incluidos en la estimación de la huella de carbono. Los hospitales tienen un impacto ambiental negativo, principalmente debido al consumo de combustibles fósiles.

  19. Estudio Experimental de Piezas Lineales de Hormigón Reforzadas con Fibras de Carbono Experimental Study of Reinforced Concrete Beams Strengthened with Carbon Fibers

    Directory of Open Access Journals (Sweden)

    M. Valcuende

    2004-01-01

    Full Text Available Se ha estudiado el comportamiento de seis vigas reforzadas simultáneamente con láminas y tejidos de fibra de carbono. Se analiza, para este tipo de refuerzos, la validez de dos de los métodos de cálculo posiblemente más utilizados. En ambos métodos se plantean las ecuaciones de equilibrio de fuerzas y momentos, pero se introducen suposiciones diferentes: i el acero tiene suficiente capacidad plástica para no romperse y ii el agotamiento se produce siempre por rotura de la lámina. Los resultados obtenidos ponen de manifiesto que refuerzos de láminas y tejidos de fibra de carbono influyen notablemente sobre las piezas, mejorando su capacidad portante y modificando su comportamiento estructural en cuanto a rigidez y ductilidadA study on the behaviour of six beams reinforced with carbon fiber laminates and fabrics was done. The validity of the two most commonly used methods of evaluating the effects of these reinforcements was analyzed. Both methods propose equilibrium equations based on forces and moments, although introducing two different suppositions: i that the steel posesses enough elasticity to avoid breakage, and ii failure is always produced by the breakage of the laminate. The results obtained demonstrate that carbon fiber laminates and fabric reinforcements have notable influence on the pieces, improving their loading capacities and modifying their structural behavior regarding stiffness and ductility

  20. Questionando a comensuração do carbono: Algumas emissões são mais iguais que outras

    Directory of Open Access Journals (Sweden)

    Ricardo Sequeiros Coelho

    2012-12-01

    Full Text Available O comércio de emissões é normalmente apresentado na literatura económica como um instrumento de regulação que permite atingir um objetivo ambiental minimizando os custos. Abrindo a “caixa negra” do processo de construção de um mercado de emissões, contudo, é possível ver como pressupõe um conjunto de processos sociais que vão influenciar a sua performance de formas não previstas pelos seus defensores.Com base na literatura crítica dos mercados de carbono, este artigo apresenta uma revisão das críticas à comensuração de emissões, enquadrando‑as numa taxonomia de argumentos baseados em ideias de rigor científico, justiça, sustentabilidade ou democracia. Estes argumentos mostram como os processos de comensuração inerentes aos mercados de carbono excluem do processo de decisão informação relevante e invisibilizam atores e instituições envolvidos. A conclusão apresenta uma discussão sobre o potencial de reforma destes mercados.

  1. AVALIAÇÃO DA FORÇA DE RETENÇÃO DE COMPOSTOS ORGÂNICOS (COV EM NANOESTRUTURAS DE CARBONO “CUP STACKED”

    Directory of Open Access Journals (Sweden)

    Waldir Nagel Schirmer

    2009-01-01

    Full Text Available Adsorventes carbonados estão entre as melhores opções na remoção de compostos orgânicos voláteis (COV de correntes gasosas, pela boa afinidade que apresentam com compostos dessa natureza, além de baixo custo e disponibilidade. O presente trabalho avalia o desempenho do ciclo adsorção/dessorção de dois compostos orgânicos voláteis (fenol e tolueno em nanotubos de carbono (NTC comparativamente a um carbono grafitizado de aplicação tipicamente analítica (Carbotrap. As metodologias de amostragem e análise empregadas compreendem a coleta de gases por bombeamento (amostragem ativa em cartuchos (tubos, contendo o material adsorvente com posterior análise por cromatografia gasosa e espectrometria de massa (CG/EM, de acordo com o Método TO-17 da USEPA. Em relação ao desempenho dos adsorventes, o nanotubo obteve clara vantagem em relação ao Carbotrap, conseguindo reter mais adsorbato por massa de adsorvente. Além disso, não foi verificada interação diferenciada do fenol e tolueno com os dois adsorventes, tanto na etapa de adsorção quanto na de dessorção.

  2. AVALIAÇÃO DA FORÇA DE RETENÇÃO DE COMPOSTOS ORGÂNICOS (COV EM NANOESTRUTURAS DE CARBONO “CUP STACKED”

    Directory of Open Access Journals (Sweden)

    Waldir Nagel Schirmer

    2008-12-01

    Full Text Available Adsorventes carbonados estão entre as melhores opções na remoção de compostos orgânicos voláteis (COV de correntes gasosas,pela boa afinidade que apresentam com compostos dessa natureza, além de baixo custo e disponibilidade. O presente trabalhoavalia o desempenho do ciclo adsorção/dessorção de dois compostos orgânicos voláteis (fenol e tolueno em nanotubos de carbono(NTC comparativamente a um carbono grafitizado de aplicação tipicamente analítica (Carbotrap. As metodologias deamostragem e análise empregadas compreendem a coleta de gases por bombeamento (amostragem ativa em cartuchos (tubos,contendo o material adsorvente com posterior análise por cromatografia gasosa e espectrometria de massa (CG/EM, de acordocom o Método TO-17 da USEPA. Em relação ao desempenho dos adsorventes, o nanotubo obteve clara vantagem em relação aoCarbotrap, conseguindo reter mais adsorbato por massa de adsorvente. Além disso, não foi verificada interação diferenciada dofenol e tolueno com os dois adsorventes, tanto na etapa de adsorção quanto na de dessorção.

  3. Alteration Summary of the 8th Edition API SPEC Q1 as Opposed to the 7th Edition%API SPEC Q1第8版相对第7版变更摘要

    Institute of Scientific and Technical Information of China (English)

    方晓东

    2009-01-01

    @@ API SPEC Q1是API标准中一项重要的技术政策性标准,通用于API的所有产品规范.API Q1第8版于2007年12月发布, 2008年6月15日生效.2008年6月15日以后对申请会标公司质量管理体系的审核,将按API Q1第8版的要求进行.

  4. Small Molecule APY606 Displays Extensive Antitumor Activity in Pancreatic Cancer via Impairing Ras-MAPK Signaling

    Science.gov (United States)

    Guo, Na; Liu, Zuojia; Zhao, Wenjing; Wang, Erkang; Wang, Jin

    2016-01-01

    Pancreatic cancer has been found with abnormal expression or mutation in Ras proteins. Oncogenic Ras activation exploits their extensive signaling reach to affect multiple cellular processes, in which the mitogen-activated protein kinase (MAPK) signaling exerts important roles in tumorigenesis. Therapies targeted Ras are thus of major benefit for pancreatic cancer. Although small molecule APY606 has been successfully picked out by virtual drug screening based on Ras target receptor, its in-depth mechanism remains to be elucidated. We herein assessed the antitumor activity of APY606 against human pancreatic cancer Capan-1 and SW1990 cell lines and explored the effect of Ras-MAPK and apoptosis-related signaling pathway on the activity of APY606. APY606 treatment resulted in a dose- and time-dependent inhibition of cancer cell viability. Additionally, APY606 exhibited strong antitumor activity, as evidenced not only by reduction in tumor cell invasion, migration and mitochondrial membrane potential but also by alteration in several apoptotic indexes. Furthermore, APY606 treatment directly inhibited Ras-GTP and the downstream activation of MAPK, which resulted in the down-regulation of anti-apoptotic protein Bcl-2, leading to the up-regulation of mitochondrial apoptosis pathway-related proteins (Bax, cytosolic Cytochrome c and Caspase 3) and of cyclin-dependent kinase 2 and Cyclin A, E. These data suggest that impairing Ras-MAPK signaling is a novel mechanism of action for APY606 during therapeutic intervention in pancreatic cancer. PMID:27223122

  5. Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular carcinoma cells through NF-kappaB pathway.

    Science.gov (United States)

    Ren, Ke; Zhang, Wei; Shi, Yujun; Gong, Jianping

    2010-06-01

    Pim-2 is proved to be relevant to the tumorigenesis of hepatocellular carcinoma (HCC), but the mechanism is unclear. We studied the relationship among Pim-2, NF-kappaB and API-5. In our experiment, expression level of the three factors and phosphorylation level of API-5, as well as NF-kappaB activity, were detected in HCC tissues and the nontumorous controls. Then Pim-2 gene was transfected into nontumorous liver cells L02, and Pim-2 SiRNA was transfected into hepatoblastoma cell line HepG2. Parthenolide was added as NF-kappaB inhibitor. The same detections as above were repeated in the cells, along with the apoptosis analysis. We found the levels of Pim-2, NF-kappaB and API-5, as well as NF-kappaB activity, were significantly higher in HCC tissues. Pim-2 level was increased in L02 cells after the transfection of Pim-2 gene, but decreased in HepG2 cells after the transfection of Pim-2 SiRNA. The levels of NF-kappaB and API-5, as well as NF-kappaB activity and API-5 phosphorylation level, were in accordance with Pim-2 level, but could be reversed by Parthenolide. Cell apoptosis rates were negatively correlated with API-5 phosphorylation level. Therefore, we infer that Pim-2 could activate API-5 to inhibit the apoptosis of liver cells, and NF-kappaB is the key regulator.

  6. El uso de las cubiertas verdes como reducción de la huella de carbono por absorción vegetal. Caso de Villaverde

    Directory of Open Access Journals (Sweden)

    Jorge Miguel Carretero Monteagudo

    2013-09-01

    Full Text Available ResumenEl tema de este trabajo es a grandes rasgos la comprobación de la eficacia de las cubiertas verdes en la reducción de la huella de carbono, centrándonos exclusivamente en las capacidades asimilativas del dióxido de carbono de la vegetación contenida sobre estas cubiertas. La presente comprobación de la eficacia de las cubiertas verdes, fue realizada sobre el contexto del distrito de Villaverde en la Periferia Sur de Madrid. Sobre este distrito, se analizaron diferentes factores en relación con la eficacia de las cubiertas verdes. Para a posteriori establecer cuáles podrían ser los casos de zona homogénea dentro del distrito que pudieran dar datos más relevantes acerca de la eficacia de las cubiertas verdes. Considerando paralelamente un análisis de las capacidades de asimilación de los diferentes tipos de cubierta verde (Intensiva y extensiva. Finalmente se establecieron cuatro escenarios de aplicación sobre las zonas más relevantes derivadas de la selección anterior, para comprobar finalmente las aportaciones en la reducción de dióxido de carbono que una cubierta verde puede aportar a un tejido urbano. Se comprobó que la eficacia de las cubiertas verdes en la absorción del dióxido de carbono es muy limitada, siendo más adecuada la regeneración natural del espacio público.Palabras clave  Reducción Dióxido Carbono Tejidos Naturalización CubiertasAbstractThe main issue of this report is the study of the green roofs reliability aimed to carbon footprint reduction, Focusing only in carbon dioxin assimilative capabilities of vegetation placed on. This study was done in the background of Villaverde district placed in the southern outskirts of Madrid. About this district, different facts related to the reliability of green roofs were analyzed, in order to remark the most relevant cases of urban fabrics within the district, whose results could be the most interesting ones about the efficiency of green roofs. In a

  7. Symptomatic nucleus of homeopathic remedies derived from carbon. Nucleo sintomático de los medicamentos homeopaticos derivados de carbono Núcleo sintomático dos medicamentos homeopáticos derivados do Carbono

    Directory of Open Access Journals (Sweden)

    Luciana Costa Lima Thomaz

    2009-03-01

    Full Text Available

    Homeopathic clinical practice requires both accuracy and agility in diagnosis and prescription of treatment during real-time consultations. Several approaches have been attempted to facilitate this process including different criteria to group homeopathic remedies. This study sought to establish whether classification according to the chemical composition of substances used as basis of homeopathic remedies have correspondence in the experimental homeopathic materia medica. Methods: The homeopathic remedies derived from carbon were selected as case-study. The experimental symptoms of these remedies were compared and a nucleus of symptoms common to all could be found. This nucleus was then compared to similarly obtained nuclei of experimental symptoms of homeopathic remedies derived from sulfur and phosphor to test qualitative specificity and finally to the traditionally described clinical picture of the so-called homeopathic carbonic constitution to establish whether the latter has homeopathic experimental grounds. Results: a nucleus of experimental symptoms common to homeopathic remedies derived from carbon was found, qualitatively different from the symptomatic nuclei of homeopathic remedies derived from sulfur and phosphor; no correlation was found, however, with the clinical image of so-called carbonic constitution.

    Keywords: Homeopathy; Materia Medica; Remedies; Classes; Carbon.

     
    Núcleo sintomático dos medicamentos homeopáticos derivados do Carbono
  1. Renovação do carbono-13 em figueiras 'Roxo de Valinhos' Carbon-13 turnover in fig trees 'Roxo de Valinhos'

    Directory of Open Access Journals (Sweden)

    Andréa Carvalho da Silva

    2011-06-01

    Full Text Available O objetivo do trabalho foi determinar a taxa de renova��ão do carbono-13 ("turnover", dos diferentes órgãos da figueira 'Roxo de Valinhos'. O experimento foi conduzido no pomar da Faculdade de Ciências Agronômicas, FCA/UNESP, Câmpus de Botucatu-SP. Determinou-se previamente, através das trocas gasosas com um medidor aberto portátil de fotossíntese, IRGA, a principal folha fotossinteticamente ativa. Essa folha foi colocada em uma câmara onde ocorreu a injeção do gás enriquecido. O tempo de enriquecimento da folha foi de 30 minutos. Os tratamentos foram constituídos por sete plantas de figueira, que foram retiradas do solo após: 6; 24; 48; 72; 120; 168 e 360 horas do enriquecimento com 13C, e suas partes seccionadas em: gema apical, folha jovem, folhas adultas (fotossinteticamente ativas, brotações laterais, frutos e ramo. Os resultados obtidos permitiram o estabelecimento da sequência de metabolização do carbono-13 nas partições estudadas: Folhas novas > Frutos > Brotações > Folhas Adultas > Gema Apical > Ramo > Folha marcada. Plantas de figueira 'Roxo de Valinhos' apresentam reciclagem do 13C de 24 horas e um tempo de meia-vida de duração do carbono-13 inferior a 11 horas.The aim of this study was to assess carbon-13 turnover in different organs of the fig tree cultivar 'Roxo de Valinhos'. The experiment was carried out in an orchard at School of Agronomical Sciences, FCA/UNESP, Botucatu Campus, São Paulo State, Brazil. The main photosynthetically active leaf was previously determined based on gas exchanges by means of an open portable photosynthesis system, IRGA. That leaf was placed in a chamber where the enriched gas injection occurred. The leaf enrichment time was 30 minutes. Treatments were constituted of seven fig trees harvested of soil after: 6; 24; 48; 72; 120; 168 and 360 hours of enrichment using 13C, and their parts were sectioned into: apical bud, young leaves, adult leaves (photosynthetically active

  2. Analysis of API2-MALT1 fusion, trisomies, and immunoglobulin VH genes in pulmonary mucosa-associated lymphoid tissue lymphoma.

    Science.gov (United States)

    Xia, Hongjing; Nakayama, Takahisa; Sakuma, Hidenori; Yamada, Seiji; Sato, Fumihiko; Takino, Hisashi; Okabe, Mitsukuni; Fujiyoshi, Yukio; Hattori, Hideo; Inagaki, Hiroshi

    2011-09-01

    Pulmonary mucosa-associated lymphoid tissue lymphoma is unique in that chronic inflammation is rare and that API2-MALT1 fusion, resulting from t(11;18)(q21;q21), occurs frequently. In this study, we examined 20 cases for API2-MALT1 fusion using the multiplex reverse-transcription polymerase chain reaction and looked for trisomy 3, trisomy 18, and abnormalities of MALT1 and IGH genes using fluorescence in situ hybridization. In addition, we analyzed VH genes by subcloning of the monoclonal polymerase chain reaction products. Of 20 cases studied, we detected gene abnormalities in 16: API2-MALT1 fusion in 9, trisomy 3 in 5, trisomy 18 in 4, MALT1 abnormality in 13, and IGH abnormality in 1. MALT1 gene abnormalities were concordant with API2-MALT1 fusion or trisomy 18. One case showed API2-MALT1 fusion and trisomy 3. On detection of API2-MALT1 fusion and trisomies, we were able to divide our cases into 3 groups, API2-MALT1 positive, trisomy positive, and no detectable gene abnormality, suggesting that tumor development had processed along different genetic pathways. All 20 cases were analyzed for VH genes. Most of the VH genes selected by the lymphomas belonged to the VH3 family, but there was no restriction to any particular VH fragment. Of interest, VH genes were unmutated in 7 cases, suggesting that T-cell-independent extrafollicular B-cell maturation may be important in the development of this lymphoma. In addition, both mutated and unmutated tumor cases were found to carry the API2-MALT1 fusion and trisomy 3. This observation suggests that these gene abnormalities may occur in microenvironments found before or outside of follicular germinal centers.

  3. 环境空气中臭氧API评价探讨%Study on Air Ozone API Evaluation

    Institute of Scientific and Technical Information of China (English)

    徐建平

    2012-01-01

    Air ozone API evaluation is considered that area of influence on ozone concentration exceed ambient air quality, ozone API correction on hours on ozone concentration exceed ambient air quality and Ozone average concentration exceed ambient air quality.%环境空气中臭氧API评价应考虑臭氧超标影响范围、臭氧超标小时数和超标平均浓度对臭氧API修正.

  4. Test-retest reliability of the Advanced Psychodiagnostic Interpretation (API) scoring system for the Bender Gestalt in chronic schizophrenics.

    Science.gov (United States)

    Aucone, E J; Wagner, E E; Raphael, A J; Golden, C J; Espe-Pfeifer, P; Dornheim, L; Seldon, J; Pospisil, T; Proctor-Weber, Z; Calabria, M

    2001-09-01

    This study assesses the test-retest reliability of the revised Advanced Psychodiagnostic Interpretation (API) scoring system for the Bender Gestalt Test (BGT). The API system identifies 207 possible distortions in a BGT protocol. Test-retest reliability for 40 schizophrenic patients tested twice with a mean interval of 6.4 years (SD=3.8 years) was good, ranging from .71 to .80. Further reliability and validity studies are needed to further demonstrate the effectiveness of the system.

  5. OWL应用接口的比较分析%Comparative Analysis of APIs for OWL Ontology

    Institute of Scientific and Technical Information of China (English)

    熊振辉; 于娟

    2015-01-01

    The paper comparatively analyzes three types of APIs for OWL, including Jena API、Protégé API and OWL API, from aspects of characteristics, platforms which they base on, languages which they can process and OWL ontology models. It focuses on commonly-used functions of OWL API and obtains related conclusions: (1) Jena API cannot achieve all functions of OWL because it bases on RDF triple;(2) OWL API is specifically designed for OWL and it supports structural specification of OWL2 which is the latest edition of OWL;(3) current APIs for OWL ontology mostly base on Java platform, whereas APIs base on other platforms (e.g. .net plat-form) have not appeared.%比较分析了Jena API、Protégé API、OWL API这三种OWL应用接口(API)的特点、所基于的平台、可处理的语言以及描述OWL本体的模型,重点介绍了OWL API的常用基本功能,得出了相关结论:(1)Jena API基于RDF三元组的特点使其不能实现OWL语言的全部功能;(2)OWL API针对OWL语言设计,且支持最新的OWL2语言的结构规范;(3)目前这些API都是基于Java平台的,对于其它平台(如.net平台),尚未见有成熟的API出现。

  6. Evaluation of different glycoforms of honeybee venom major allergen phospholipase A2 (Api m 1) produced in insect cells

    DEFF Research Database (Denmark)

    Blank, Simon; Seismann, Henning; Plum, Melanie;

    2011-01-01

    Allergic reactions to hymenoptera stings are one of the major reasons for IgE-mediated anaphylaxis. However, proper diagnosis using venom extracts is severely affected by molecular cross-reactivity. In this study recombinant honeybee venom major allergen phospholipase A2 (Api m 1) was produced......-derived recombinant Api m 1 with defined CCD phenotypes might provide further insights into hymenoptera venom IgE reactivities and contribute to an improved diagnosis of hymenoptera venom allergy....

  7. The API2-MALT1 fusion exploits TNFR pathway-associated RIP1 ubiquitination to promote oncogenic NF-κB signaling.

    Science.gov (United States)

    Rosebeck, S; Rehman, A O; Apel, I J; Kohrt, D; Appert, A; O'Donnell, M A; Ting, A T; Du, M-Q; Baens, M; Lucas, P C; McAllister-Lucas, L M

    2014-05-08

    The API2-MALT1 fusion oncoprotein is created by the recurrent t(11;18)(q21;q21) chromosomal translocation in mucosa-associated lymphoid tissue (MALT) lymphoma. We identified receptor interacting protein-1 (RIP1) as a novel API2-MALT1-associated protein, and demonstrate that RIP1 is required for API2-MALT1 to stimulate canonical nuclear factor kappa B (NF-κB). API2-MALT1 promotes ubiquitination of RIP1 at lysine (K) 377, which is necessary for full NF-κB activation. Furthermore, we found that TNF receptor-associated factor 2 (TRAF2) recruitment is required for API2-MALT1 to induce RIP1 ubiquitination, NF-κB activation and cellular transformation. Although both TRAF2 and RIP1 interact with the API2 moiety of API2-MALT1, this moiety alone is insufficient to induce RIP1 ubiquitination or activate NF-κB, indicating that API2-MALT1-dependent RIP1 ubiquitination represents a gain of function requiring the concerted actions of both the API2 and MALT1 moieties of the fusion. Intriguingly, constitutive RIP1 ubiquitination was recently demonstrated in several solid tumors, and now our study implicates RIP1 ubiquitination as a critical component of API2-MALT1-dependent lymphomagenesis.

  8. Comparative proteomic analysis reveals mite (Varroa destructor) resistance-related proteins in Eastern honeybees (Apis cerana).

    Science.gov (United States)

    Ji, T; Shen, F; Liu, Z; Yin, L; Shen, J; Liang, Q; Luo, Y X

    2015-08-21

    The mite (Varroa destructor) has become the greatest threat to apiculture worldwide. As the original host of the mite, Apis cerana can effectively resist the mite. An increased understanding of the resistance mechanisms of Eastern honeybees against V. destructor may help researchers to protect other species against these parasites. In this study, the proteomes of 4 Apis cerana colonies were analyzed using an isobaric tag for relative and absolute quantitation technology. We determined the differences in gene and protein expression between susceptible and resistant colonies that were either unchallenged or challenged by V. destructor. The results showed that a total of 1532 proteins were identified. Gene Ontology enrichment analysis suggested that the transcription factors and basic metabolic and respiratory processes were efficient and feasible factors controlling this resistance, and 12 differentially expressed proteins were identified in Venn analysis. The results were validated by quantitative polymerase chain reaction. This study may provide insight into the genetic mechanisms underlying the resistance of honeybee to mites.

  9. Developing a Digital Video Library with the YouTube Data API

    Directory of Open Access Journals (Sweden)

    Jason Clark

    2013-04-01

    Full Text Available MSU Library has created a digital video library using the YouTube API to power our local library channel. It is a complete search and browse application with item level views, microdata, a caching and optimization routine, and a file backup routine. The article will discuss applying the YouTube API as a database application layer: workflow efficiencies, metadata procedures and local backup and optimization procedures. Code samples in PHP, .htaccess examples, and shell commands used in developing the application and routines will be explained at length. And finally, a complete prototype application will be released on github for other libraries to get started using the lessons learned. A live version of the application is here: http://www.lib.montana.edu/channel/. The real benefit of this method is the low overhead for smaller shops and the ability to scale production and distribution of digital video.

  10. Temporal genetic structure of a drone congregation area of the giant Asian honeybee (Apis dorsata).

    Science.gov (United States)

    Kraus, F B; Koeniger, N; Tingek, S; Moritz, R F A

    2005-12-01

    The giant Asian honeybee (Apis dorsata), like all other members of the genus Apis, has a complex mating system in which the queens and males (drones) mate at spatially defined drone congregation areas (DCAs). Here, we studied the temporal genetic structure of a DCA of A. dorsata over an 8-day time window by the genotyping of sampled drones with microsatellite markers. Analysis of the genotypic data revealed a significant genetic differentiation between 3 sampling days and indicated that the DCA was used by at least two subpopulations at all days in varying proportions. The estimation of the number of colonies which used the DCA ranged between 20 and 40 colonies per subpopulation, depending on the estimation procedure and population. The overall effective population size was estimated as high as N (e)=140. The DCA seems to counteract known tendencies of A. dorsata for inbreeding within colony aggregations by facilitating gene flow among subpopulations and increasing the effective population size.

  11. Opening the Door: A First Look at the OCLC WorldCat Metadata API

    Directory of Open Access Journals (Sweden)

    Terry Reese

    2014-07-01

    Full Text Available Libraries have long relied on OCLC’s WorldCat database as a way to cooperatively share bibliographic data and declare library holdings to support interlibrary loan services. As curator, OCLC has traditionally mediated all interactions with the WorldCat database through their various cataloging clients to control access to the information. As more and more libraries look for new ways to interact with their data and streamline metadata operations and workflows, these clients have become bottlenecks and an inhibitor of library innovation. To address some of these concerns, in early 2013 OCLC announced the release of a set of application programming interfaces (APIs supporting read and write access to the WorldCat database. These APIs offer libraries their first opportunity to develop new services and workflows that directly interact with the WorldCat database, and provide opportunities for catalogers to begin redefining how they work with OCLC and their data.

  12. Bauschinger effect on API 5L B and X56 steel plates under repeating bending load

    Science.gov (United States)

    Chandra, Icho Y.; Korda, Akhmad A.

    2017-01-01

    During steel pipe fabrication, hot rolled coil steel will undergo coiling and uncoiling process, where the steel plate is bent repeatedly. When cyclic loading is imposed on steel, tensile and compressive stress will occur in it resulting in softening caused by Bauschinger effect. This research is focused on Bauschinger effect and cyclic loading during coiling and uncoiling process on API 5L B and API 5L X56 steel. Both types of steel were given repeated bend loading with variation in loading cycle and the curvature radius. The steel's response was then observed by using tensile testing, microhardness testing, and microstructure observation. A decrease in yield strength is observed during lower cycles and on smaller radii. After higher loading cycle, the yield strength of the steel was increased. Microhardness testing also reported similar results on the subsurface part of the steel where loading is at its highest.

  13. TogoWS: integrated SOAP and REST APIs for interoperable bioinformatics Web services.

    Science.gov (United States)

    Katayama, Toshiaki; Nakao, Mitsuteru; Takagi, Toshihisa

    2010-07-01

    Web services have become widely used in bioinformatics analysis, but there exist incompatibilities in interfaces and data types, which prevent users from making full use of a combination of these services. Therefore, we have developed the TogoWS service to provide an integrated interface with advanced features. In the TogoWS REST (REpresentative State Transfer) API (application programming interface), we introduce a unified access method for major database resources through intuitive URIs that can be used to search, retrieve, parse and convert the database entries. The TogoWS SOAP API resolves compatibility issues found on the server and client-side SOAP implementations. The TogoWS service is freely available at: http://togows.dbcls.jp/.

  14. Beginning the 21st century with advanced Automatic Parts Identification (API)

    Science.gov (United States)

    Schramm, Fred; Roxby, Don

    1994-01-01

    Under the direction of the NASA George C. Marshall Space Flight Center, Huntsville, Alabama, the development and commercialization of an advanced Automated Parts Indentification (API) system is being undertaken by Rockwell International Corporation. The new API system is based on a variable sized, machine-readable, two-dimensioanl matrix symbol that can be applied directly onto most metallic and nonmetallic materials using safe, permanent marking methods. Its checkerboard-like structure is the most space efficient of all symbologies. This high data-density symbology can be applied to products of different material sizes and geometries using application-dependent, computer-driven marking devices. The high fidelity markings produced by these devices can then be captured using a specially designed camera linked to any IBM-compatible computer. Applications of compressed symbology technology will reduce costs and improve quality, productivity, and processes in a wide variety of federal and commercial applications.

  15. Genetic reincarnation of workers as queens in the Eastern honeybee Apis cerana.

    Science.gov (United States)

    Holmes, M J; Tan, K; Wang, Z; Oldroyd, B P; Beekman, M

    2015-01-01

    Thelytokous parthenogenesis, or the asexual production of female offspring, is rare in the animal kingdom, but relatively common in social Hymenoptera. However, in honeybees, it is only known to be ubiquitous in one subspecies of Apis mellifera, the Cape honeybee, A. mellifera capensis. Here we report the appearance of queen cells in two colonies of the Eastern honeybee Apis cerana that no longer contained a queen or queen-produced brood to rear queens from. A combination of microsatellite genotyping and the timing of the appearance of these individuals excluded the possibility that they had been laid by the original queen. Based on the genotypes of these individuals, thelytokous production by natal workers is the most parsimonious explanation for their existence. Thus, we present the first example of thelytoky in a honeybee outside A. mellifera. We discuss the evolutionary and ecological consequences of thelytoky in A. cerana, in particular the role thelytoky may play in the recent invasions by populations of this species.

  16. csd alleles in the red dwarf honey bee (Apis florea,Hymenoptera: Apidae) show exceptionally high nucleotide diversity

    Institute of Scientific and Technical Information of China (English)

    Zhi-Yong Liu; Zi-Long Wang; Xiao-Bo Wu; Wei-Yu Yan; Zhi-Jiang Zeng

    2011-01-01

    The single locus complementary sex determination (sl-csd) gene is the primary gene determining the gender of honey bees (Apis spp.).While the csd gene has been well studied in the Western honey bee (Apis mellifera),and comparable data exist in both the Eastern honey bee (Apis cerana) and the giant honey bee (Apis dorsata),no studies have been conducted in the red dwarf honey bee,Apisflorea.In this study we cloned the genomic region 3 of the A.florea csd gene from 60 workers,and identified 12 csd alleles.Analysis showed that similar to A.mellifera,region 3 of the csd gene contains a RS domain at the N terminal,a proline-rich domain at the C terminal,and a hypervariable region in the middle.However,the A.florea csd gene possessed a much higher level of nucleotide diversity,compared to A.mellifera,A.cerana and Apis dorsata.We also show that similar to the other three Apis species,in A.florea,nonsynonymous mutations in the csd gene are selectively favored in young alleles.

  17. Novel insights into excipient effects on the biopharmaceutics of APIs from different BCS classes: Lactose in solid oral dosage forms.

    Science.gov (United States)

    Kubbinga, Marlies; Moghani, Laura; Langguth, Peter

    2014-09-30

    Excipients encompass a wide range of properties that are of importance for the resulting drug product. Regulatory guidelines on biowaivers for immediate release formulations require an in depth understanding of the biopharmaceutic effects of excipients in order to establish bioequivalence between two different products carrying the same API based on dissolution tests alone. This paper describes a new approach in evaluating biopharmaceutic excipient effects. Actually used quantities of a model excipient, lactose, formulated in combination with APIs from different BCS classes were evaluated. The results suggest that companies use different (relative) amounts depending on the characteristics of the API. The probability of bioinequivalence due to a difference in lactose content between test and reference products was classified as low for BCS class I APIs and medium for BCS class II and III APIs, whereas a high probability was assigned to the combination of lactose and BCS class IV APIs. If repeated for other excipients, this retrospective, top-down approach may lead to a new database and more widespread applications of the biowaiver approach.

  18. Dry coating of micronized API powders for improved dissolution of directly compacted tablets with high drug loading.

    Science.gov (United States)

    Han, Xi; Ghoroi, Chinmay; Davé, Rajesh

    2013-02-14

    Motivated by our recent study showing improved flow and dissolution rate of the active pharmaceutical ingredient (API) powders (20 μm) produced via simultaneous micronization and surface modification through continuous fluid energy milling (FEM) process, the performance of blends and direct compacted tablets with high drug loading is examined. Performance of 50 μm API powders dry coated without micronization is also considered for comparison. Blends of micronized, non-micronized, dry coated or uncoated API powders at 30, 60 and 70% drug loading, are examined. The results show that the blends containing dry coated API powders, even micronized ones, have excellent flowability and high bulk density compared to the blends containing uncoated API, which are required for direct compaction. As the drug loading increases, the difference between dry coated and uncoated blends is more pronounced, as seen in the proposed bulk density-FFC phase map. Dry coating led to improved tablet compactibility profiles, corresponding with the improvements in blend compressibility. The most significant advantage is in tablet dissolution where for all drug loadings, the t(80) for the tablets with dry coated APIs was well under 5 min, indicating that this approach can produce nearly instant release direct compacted tablets at high drug loadings.

  19. Hydrogen sulfide corrosion of weld regions in API X52 steel; Corrosion por acido sulfhidrico de las regiones de soldadura en acero API X52

    Energy Technology Data Exchange (ETDEWEB)

    Arenas-Martinez, L.F [Universidad Autonoma de Coahuila, Coahuila (Mexico)]. E-mail: fernando.arenas@uadec.edu.mx; Garcia-Cerecero, G. [Corporacion Mexicana de Investigacion en Materiales S.A. de C.V., Saltillo, Coahuila (Mexico)]. E-mail: ggarcia@comimsa.com

    2012-10-15

    The corrosion behavior of gas metal arc welding (GMAW) regions has been studied using potentiodynamic polarization and polarization resistance (LPR) techniques. Experiments were conducted in hydrogen sulfide (H{sub 2}S)-containing brine and in H{sub 2}S-free brine. Welds were made on API 5L X52 steel. Due to differences in their microstructure, chemical composition and residual stress level, weld regions exhibited different responses under H{sub 2}S corrosion. Base metal exhibited the highest corrosion rate (CR) and the most cathodic corrosion potential. [Spanish] Se estudio el comportamiento ante la corrosion de las regiones de soldadura de un cordon realizado por arco metalico con gas (GMAW) sobre un acero grado API X52 mediante las tecnicas de polarizacion potencio dinamica y resistencia a la polarizacion (LPR). Los experimentos se realizaron utilizando salmuera con 300 ppm de acido sulfhidrico (H{sub 2}S) y salmuera libre de H{sub 2}S como electrolitos. Debido a las diferencias en su microestructura, composicion quimica y el nivel de esfuerzos residuales, las regiones de soldadura mostraron diferentes respuestas a la corrosion por H{sub 2}S. El metal base exhibio la velocidad de corrosion (VC) mas alta y el potencial de corrosion mas catodico.

  20. Efeitos de atrativos e repelentes sobre o comportamento da abelha (Apis mellifera, l. Effect of attractants and repellents on the behavior of honey bees (Apis mellipera, L.

    Directory of Open Access Journals (Sweden)

    D.T. MALERBO-SOUZA

    1998-01-01

    Full Text Available O objetivo do presente ensaio foi testar diversas substâncias e verificar sua atratividade e repelência para abelhas, Apis mellifera, L. Para isso, foram realizados testes em discos próximos às colméias e em cana picada oferecida como alimentação para gado bovino confinado. Nos discos próximos à colméia, o produto mais atrativo foi Bee-Here e o mais repelente foi o óleo de citronela. No cocho para bovinos, o repelente mais efetivo foi n-octyl-acetato.The experiment aimed to study honey bee (Apis mellifera attractants and repellents in vitro and on chopped sugar cane for bovine feeding. Tests were performed on plates located near to the hives and on bovine-hods. On plates, Bee-Here® was the most attractive and citronela oil the most repellent. On bovine-hods the most effective was n-octyl-acetate.

  1. Protease activity of the API2-MALT1 fusion oncoprotein in MALT lymphoma development and treatment.

    Science.gov (United States)

    Rosebeck, Shaun; Lucas, Peter C; McAllister-Lucas, Linda M

    2011-05-01

    Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is a prototypical cancer that occurs in the setting of chronic inflammation and an important model for understanding how deregulated NF-κB transcriptional activity contributes to malignancy. Most gastric MALT lymphomas require ongoing antigenic stimulation for continued tumor growth, and Stage I disease is usually cured by eradicating the causative microorganism, Helicobacter pylori, with antibiotics. However, in a subset of MALT lymphomas, chromosomal translocations are acquired that render the lymphoma antigen-independent. The recurrent translocation t(11;18)(q21;q21) is associated with failure to respond to antibiotic therapy and increased rate of dissemination. This translocation creates the API2-MALT1 fusion oncoprotein, which comprises the amino terminus of inhibitor of apoptosis 2 (API2 or cIAP2) fused to the carboxy terminus of MALT1. A common characteristic of chromosomal translocations in MALT lymphoma, including t(11;18), is that genes involved in the regulation of the NF-κB transcription factor are targeted by the translocations, and these genetic perturbations thereby result in deregulated, constitutive NF-κB stimulation. In the last decade, great insights into the roles of API2 and MALT1 in NF-κB signaling have been made. For example, recent pivotal studies have uncovered the long sought-after proteolytic activity of MALT1 and have demonstrated its critical involvement in the survival of certain lymphomas. Here, we review the current understanding of the role of MALT1 in normal lymphocyte function and lymphomagenesis. We then highlight our recent work that has revealed an intriguing link between the proteolytic activity of the API2-MALT1 fusion and its ability to influence lymphomagenesis by cleaving a key NF-κB regulatory protein, NF-κB-inducing kinase.

  2. Manipulating API and AOD data to distinguish transportation of aerosol at high altitude in Penang, Malaysia

    Science.gov (United States)

    Tan, F.; Lim, H. S.; Abdullah, K.; Yoon, T. L.; Matjafri, M. Z.; Holben, B.

    2014-02-01

    Air pollution index (API) is an index commonly used in Malaysia to determine the air quality level. It is a ground truth data measurement which is unable to unambiguously quantify air quality level at higher atmosphere. On the other hand, aerosol optical depth (AOD) from AERONET data obtained using sun photometer provides reading of the air quality for a column of atmosphere from ground surface. We first determine the quantitative correlation between the API and AOD data collected in Penang, Malaysia, between January - September, 2012, using two independent methods, one based on regression analysis and the other interpolation. Our purpose is to establish a systematic numerical procedure to determine whether aerosol transported in high altitude from other location has occurred. Two independent methods for establishing the quantitative relationship between the API and AOD data were used as a way to facilitate the verification of our approach. In our method, data from southwest monsoon period (August to September) were used as "calibration dataset" to establish the quantitative correlation between the AOD and API data. The established calibrated coefficients is then used to predict the AOD of other months, which are then compared against the data actually measured. Discrepancy between the predicted and measured AOD data can then be interpreted as an indication of whether the atmosphere at high altitude is polluted by aerosol transported from other location. If the predicted AOD is much larger than that measured, back trajectory analysis was applied to identify the aerosol transported source. This procedure is very helpful to investigate the aerosol transportation and distribution patterns during monsoon and non monsoon periods.

  3. The nicotinic acetylcholine receptor gene family of the honey bee, Apis mellifera

    OpenAIRE

    Jones, Andrew K.; Raymond-Delpech, Valerie; Steeve H Thany; Gauthier, Monique; Sattelle, David B.

    2006-01-01

    Nicotinic acetylcholine receptors (nAChRs) mediate fast cholinergic synaptic transmission and play roles in many cognitive processes. They are under intense research as potential targets of drugs used to treat neurodegenerative diseases and neurological disorders such as Alzheimer's disease and schizophrenia. Invertebrate nAChRs are targets of anthelmintics as well as a major group of insecticides, the neonicotinoids. The honey bee, Apis mellifera, is one of the most beneficial insects worldw...

  4. Hydrocarbon Composition of Beeswax (Apis Mellifera) Collected from Light and Dark Coloured Combs

    OpenAIRE

    Waś Ewa; Szczęsna Teresa; Rybak-Chmielewska Helena

    2014-01-01

    The hydrocarbon composition of beeswax secreted by Apis mellifera was characterised. In the studies, analyses were made of virgin beeswax (obtained from light combs, socalled „wild-built combs“) that was collected at different dates, and beeswax obtained from dark combs („brood combs“). A qualitative analysis did not show any differences in the hydrocarbon composition of beeswax originating from light and dark coloured combs. The same hydrocarbons (n-alkanes, alkenes, and dienes) were identif...

  5. Microstructure and mechanical properties of two API steels for iron ore pipelines.

    OpenAIRE

    Godefroid,Leonardo Barbosa; Cândido,Luiz Cláudio; Toffolo,Rodrigo Vicente Bayão; Barbosa,Luiz Henrique Soares

    2014-01-01

    This research compares the mechanical behavior of two API steels (X60 and X70) used in the longest pipeline in the world for the conveyance of iron ore. Tensile tests, Charpy impact tests, CTOD tests and fatigue crack growth tests are performed at ambient temperature. Metallographic examination showed a banded microstructure consisting of polygonal ferrite and pearlite in both steels, with smaller grain size and the presence of a small quantity of bainite in the X70 steel. All the mechanical ...

  6. Galenics: studies of the toxicity and distribution of sugar substitutes on Apis mellifera

    OpenAIRE

    RADEMACHER, Eva; Fahlberg, Anja; Raddatz, Marlene; Schneider, Saskia; Voigt, Kathrin

    2013-01-01

    International audience; The aim of this study was to find a substitute to sugar water in medicinal treatments of honey bee colonies with the same properties but without being ingested by bees or being toxic to them. Tylose MH, sorbitol and glycerol were tested for their attractiveness to Apis mellifera, their application ability, toxicity via individual application and distribution in small groups respectively a small colony. Neither of the substances proved attractive or toxic. All had good ...

  7. Use of oxalic acid to control Varroa destructor in honeybee (Apis mellifera L.) colonies

    OpenAIRE

    Akyol, Ethem; YENİNAR, Halil

    2009-01-01

    This study was carried out to determine the effects of oxalic acid (OA) on reducing Varroa mite (Varroa destructor) populations in honeybee (Apis mellifera L.) colonies in the fall. Twenty honeybee colonies, in wooden Langstroth hives, were used in this experiment. Average Varroa infestation levels (%) of the OA and control groups were 25.87% and 24.57% on adult workers before the treatments. The OA treatments were applied twice, on 3 November and 13 November 2006. Average Varroa infestation ...

  8. Phosphorus 30 CH to control Varroa population in Apis mellifera colonies

    OpenAIRE

    Moscatelli, Francesca; Pietropaoli, Marco; Brocherel, Giuseppina; Martini, Andrea; Formato, Giovanni

    2016-01-01

    Varroa destructor is considered to be the main cause of European honeybee (Apis mellifera ssp. Linnaeus 1758) colony losses. The use of homeopathic products in veterinary practices has consistently increased in the last 50 years, but limited data are available on the application of homeopathic treatments to honeybees. The aims of this study were to investigate the acaricide efficacy and tolerability for honeybees treated for 35 days with the homeopathic product Phosphorus 30 CH. Methods...

  9. Transcriptional markers of sub-optimal nutrition in developing Apis mellifera nurse workers

    OpenAIRE

    Corby-Harris, Vanessa; Jones, Beryl M.; Walton, Alexander; Schwan, Melissa R; Kirk E Anderson

    2014-01-01

    Background Honey bees (Apis mellifera) contribute substantially to the worldwide economy and ecosystem health as pollinators. Pollen is essential to the bee’s diet, providing protein, lipids, and micronutrients. The dramatic shifts in physiology, anatomy, and behavior that accompany normal worker development are highly plastic and recent work demonstrates that development, particularly the transition from nurse to foraging roles, is greatly impacted by diet. However, the role that diet plays ...

  10. Studies of the eddy structure in the lower ionosphere by the API technique

    Science.gov (United States)

    Bakhmetieva, Nataliya V.; Grigoriev, Gennadii I.; Lapin, Victor G.

    2016-07-01

    We present a new application of the API technique to study of turbulent phenomena in the lower ionosphere. The main objective of these studies is experimental diagnostics of natural ordered eddy structures at the altitudes of the mesosphere and lower thermosphere, such as those that occur when internal gravity waves propagate in stratified flows in the atmospheric boundary layer. To this end, we considered the impact of eddy motions in the mesosphere and lower thermosphere on the relaxation time and the frequency of the signal scattered by periodic irregularities. Theoretical study of eddy structures base on experiments using SURA heating facility (56,14 N; 44,1 W). It is known, artificial periodic irregularities (APIs) are formed in the field of the powerful standing wave as a result of the interference of the incident wave and reflected from the ionosphere (Belikovich et al., Ionospheric Research by Means of Artificial Periodic Irregularities - 2002. Katlenburg-Lindau, Germany. Copernicus GmbH. 160 p.). The relaxation or decay of the periodic structure is specified by the ambipolar diffusion process. The atmospheric turbulence causes reduction of the amplitude and decay time of the API scattered signal in comparison with the diffusion time. We found a relation between the eddy period and the characteristic decay time of scattered signal, for which the synchronism of the waves scattered by a periodic structure is broken. Besides, it is shown, when the eddy structure moves by a horizontal wind exists at these heights, the frequency of the radio wave scattered by API structure will periodically increase and decrease compared with the frequency of the radiated diagnostic (probing) radio-wave. The work was supported by the Russian Science Foundation under grant No 14-12-00556.

  11. Comparison of ground based indices (API and AQI) with satellite based aerosol products.

    Science.gov (United States)

    Zheng, Sheng; Cao, Chun-Xiang; Singh, Ramesh P

    2014-08-01

    Air quality in mega cities is one of the major concerns due to serious health issues and its indirect impact to the climate. Among mega cities, Beijing city is considered as one of the densely populated cities with extremely poor air quality. The meteorological parameters (wind, surface temperature, air temperature and relative humidity) control the dynamics and dispersion of air pollution. China National Environmental Monitoring Centre (CNEMC) started air pollution index (API) as of 2000 to evaluate air quality, but over the years, it was felt that the air quality is not well represented by API. Recently, the Ministry of Environmental Protection (MEP) of the People's Republic of China (PRC) started using a new index "air quality index (AQI)" from January 2013. We have compared API and AQI with three different MODIS (MODIS - Moderate Resolution Imaging SpectroRadiometer, onboard the Terra/Aqua satellites) AOD (aerosol optical depth) products for ten months, January-October, 2013. The correlation between AQI and Aqua Deep Blue AOD was found to be reasonably good as compared with API, mainly due to inclusion of PM2.5 in the calculation of AQI. In addition, for every month, the correlation coefficient between AQI and Aqua Deep Blue AOD was found to be relatively higher in the month of February to May. According to the monthly average distribution of precipitation, temperature, and PM10, the air quality in the months of June-September was better as compared to those in the months of February-May. AQI and Aqua Deep Blue AOD show highly polluted days associated with dust event, representing true air quality of Beijing.

  12. An analysis of the intrinsic cross-correlations between API and meteorological elements using DPCCA

    Science.gov (United States)

    Shen, Chen-hua; Li, Cao-ling

    2016-03-01

    In order to reveal the intrinsic cross-correlations between air pollution index (API) records and synchronously meteorological elements data, the detrended partial cross-correlation (DPCC) coefficients are analyzed using a detrended partial cross-correlation analysis (DPCCA). DPCC coefficients for different spatial locations and seasons are calculated and compared. The results show that DPCCA can uncover intrinsic cross-correlations between API and meteorological elements, and most of their interactional mechanisms can be explained. DPCC coefficients are either positive or negative, and vary with spatial locations and seasons, with consistently interactional mechanisms. More remarkable, we find that detrended cross-correlation analysis can present the cross-correlations between the fluctuations in two nonstationary time series, but this cross-correlation does not always fully reflect the interactional mechanism for the original time series. Despite this, DPCCA is recommended as a comparatively reliable method for revealing intrinsic cross-correlations between API and meteorological elements, and it can also be useful for our understanding of their interactional mechanisms.

  13. Super-Atmospheric Pressure Ion Sources: Application and Coupling to API Mass Spectrometer.

    Science.gov (United States)

    Chen, Lee Chuin; Rahman, Md Matiur; Hiraoka, Kenzo

    2014-01-01

    Pressurizing the ionization source to gas pressure greater than atmospheric pressure is a new tactic aimed at further improving the performance of atmospheric pressure ionization (API) sources. In principle, all API sources, such as ESI, APCI and AP-MALDI, can be operated at pressure higher than 1 atm if suitable vacuum interface is available. The gas pressure in the ion source can have different role for different ionization. For example, in the case of ESI, stable electrospray could be sustained for high surface tension liquid (e.g., pure water) under super-atmospheric pressure, owing to the absence of electric discharge. Even for nanoESI, which is known to work well with aqueous solution, its stability and sensitivity were found to be enhanced, particularly in the negative mode when the ion source was pressurized. For the gas phase ionization like APCI, measurement of gaseous compound also showed an increase in ion intensity with the ion source pressure until an optimum pressure at around 4-5 atm. The enhancement was due to the increased collision frequency among reactant ion and analyte that promoted the ion/molecule reaction and a higher intake rate of gas to the mass spectrometer. Because the design of vacuum interface for API instrument is based on the upstream pressure of 1 atm, some coupling aspects need to be considered when connecting the high pressure ion source to the mass spectrometer. Several coupling strategies are discussed in this paper.

  14. PEMANFAATAN TEKNOLOGI GOOGLE MAPS API UNTUK APLIKASI LAPORAN KRIMINAL BERBASIS ANDROID PADA POLRESTABES MAKASSAR

    Directory of Open Access Journals (Sweden)

    Rismayani Rismayani

    2016-12-01

    Full Text Available Polrestabes Makassar adalah institusi negara yang berada di bawah naungan kepolisian daerah Sulawesi Selatan yang memiliki tugas dan tanggung jawab untuk melayani masyarakat kota Makassar dalam proses penanganan berbagai macam permasalahan keamanan dan kriminalitas pada masyarakat kota Makassar. Adapun permasalahan pada penelitian ini adalah bagaimana masyarakat dapat melaporkan tindak kriminal yang terjadi di sekitar mereka tanpa harus datang ke kantor polisi dan bagaimana aparat dapat menerima langsung laporan kriminal dari masyarakat tanpa harus bertemu dan dapat melihat kejadian  dari foto yang dikirimkan serta dapat mengetahui lokasi kejadian tindak kriminal di wilayah kota Makassar. Tujuan dari penelitian ini adalah membuat aplikasi berbasis android dengan memanfaatkan teknologi Google Maps API untuk mengirim laporan kriminal dalah bentuk foto serta mengirimkan lokasi kejadian tindak kriminal dari masyarakat ke aparat kepolisian. Adapun metode atau teknologi yang digunakan adalah Google Maps API dan berbasis Android, google maps api adalah adalah sebuah jasa peta global virtual gratis dan online yangdisediakan oleh perusahaan Google. Google Maps yang dapat ditemukan di alamat http://maps.google.com  dan berbasis android adalah sistem operasi berbasis Linux yang dirancang untuk perangkat bergerak layar sentuh seperti telepon pintar dan komputer tablet. Hasil dari penelitian ini adalah dengan adanya aplikasi tersebut maka masyarakat dapat melaporkan tindak kriminal yang terjadi di sekitar mereka tanpa harus datang ke kantor polisi dan memudahkan para aparat kepolisian untuk melihat laporan kriminal dari masyarakat dengan melihat gambar dan lokasi kejadian kriminal.

  15. CernVM WebAPI - Controlling Virtual Machines from the Web

    Science.gov (United States)

    Charalampidis, I.; Berzano, D.; Blomer, J.; Buncic, P.; Ganis, G.; Meusel, R.; Segal, B.

    2015-12-01

    Lately, there is a trend in scientific projects to look for computing resources in the volunteering community. In addition, to reduce the development effort required to port the scientific software stack to all the known platforms, the use of Virtual Machines (VMs)u is becoming increasingly popular. Unfortunately their use further complicates the software installation and operation, restricting the volunteer audience to sufficiently expert people. CernVM WebAPI is a software solution addressing this specific case in a way that opens wide new application opportunities. It offers a very simple API for setting-up, controlling and interfacing with a VM instance in the users computer, while in the same time offloading the user from all the burden of downloading, installing and configuring the hypervisor. WebAPI comes with a lightweight javascript library that guides the user through the application installation process. Malicious usage is prohibited by offering a per-domain PKI validation mechanism. In this contribution we will overview this new technology, discuss its security features and examine some test cases where it is already in use.

  16. O SUDÁRIO DE TURIM: ENTRE A HISTÓRIA DA ARTE E A DATAÇÃO DO CARBONO 14

    Directory of Open Access Journals (Sweden)

    Prof. Dr. Antônio Jackson de Souza Brandão

    2014-03-01

    Full Text Available Quando se publicaram, em 1989, os resultados do teste do Carbono 14 do Sudário de Turim, muitos cientistas, agnósticos e teístas de diversas agremiações religiosas não católicas comemoraram seu resultado diante do “desmascaramento” da estranha relíquia. Esqueceram-se, porém, de que a história da arte, mais do que documentada há séculos, demonstra exatamente o contrário: sua confecção imagética seria inconcebível entre 1260 a 1390, período apontado como de sua provável criação.

  17. ALGUNOS RESULTADOS SOBRE LAS PÉRDIDAS DE CARBONO EN ECOSISTEMAS CON SUELOS FERRALÍTICOS ROJOS LIXIVIADOS EN CLIMA TROPICAL SUBHÚMEDO DE CUBA

    OpenAIRE

    2007-01-01

    Se determinan las reservas de carbono en dos ecosistemas de suelos Ferralíticos Rojos Lixiviados de Cuba (Ferrálicos Nitisoles Ródicos), en la llanura roja formada de roca caliza en la región de San José de las Lajas, La Habana, y en las Alturas de Pizarras de la región de La Palma, Pinar del Río. En ambos casos, se hacen los cálculos con patrones comparativos desde suelos con vegetación conservada y suelos cultivados durante muchos años. Para la región de San José de las Lajas, se estudiaron...

  18. IMPLANTACIÓN DE ENERGIAS RENOVABLES Y ESTIMACIÓN DE LA HUELLA DE CARBONO EN EL MUNICIPIO DE BLANCA (MURCIA

    Directory of Open Access Journals (Sweden)

    José Molina Ruiz

    2012-01-01

    Full Text Available La introducción del concepto de sostenibilidad en el mercado energético implica la potenciación de las energías renovables activando políticas que fomenten su implantación. El éxito de estas políticas se plasmará en el incremento de participación de las energías renovables en el mix energético, en la reducción de emisiones de CO2 y en el cumplimiento de los compromisos internacionales. Este trabajo analiza el grado de implantación de las energías renovables en un municipio de la Región de Murcia (Blanca, valorando la incidencia de la legislación sectorial energética y estimando la huella de carbono derivada del consumo de energía eléctrica.

  19. Emprego do glicerol como fonte de carbono na produção fermentativa de 2,3-Butanodiol por Enterobacter aerogenes ATCC 13048

    OpenAIRE

    Girardi, Viviane

    2014-01-01

    Neste trabalho, estudou-se o uso de glicerol como fonte de carbono para o crescimento celular e a produção de 2,3-butanodiol/acetoína em cultivo de Enterobacter aerogenes ATCC 13048. A influência da concentração inicial do substrato (S0) e da velocidade de transferência de oxigênio (OTR) foi avaliada em ensaios em regime descontínuo. Inicialmente, foram realizados cultivos com S0 na faixa aproximada de 20 a 180 g/L, frequência dos agitadores de 500 rpm e fluxo específico de ar de 0,50 vvm, co...

  20. Determinação espectrofotométrica da caboxiemoglobinemia em indivíduos expostos ocupacionalmente ao monóxido de carbono

    OpenAIRE

    Ana Cristina Calhabeutt Gabriel da Costa Malheiro

    1991-01-01

    O monóxido de carbono (CO) constitui sério risco à saúde de indivíduos expostos a este gás. Os efeitos nocivos aparecem como conseqüência de sua combinação com a hemoglobina formando a carboxiemoglobina(COHb). A avaliação da exposição ao CO pela monitorização biológica é realizada, preferencialmente, pela determinação da carboxiemoglobinemia. O método espectrofotométrico proposto, para a determinação de COHb, utiliza a leitura na região Soret (420 e 432 nm) e fatores de calibração do espectro...

  1. Glutamina e turnover do carbono da mucosa intestinal de leitões desmamados Glutamine and carbon turnover of the intestinal mucosa of weaned piglets

    Directory of Open Access Journals (Sweden)

    Fabiana Ribeiro Caldara

    2010-12-01

    Full Text Available Um experimento foi conduzido para verificar a influência da glutamina no turnover do carbono na mucosa intestinal de leitões desmamados. Nove matrizes receberam dietas compostas basicamente de plantas do ciclo fotossintético C4 durante toda a gestação (d‰13C = 17,12 e lactação (d‰13C = -19,26. Os leitões foram desmamados aos 21 dias de idade e 68 deles foram alimentados com ração composta de plantas do ciclo fotossintético C3 (d‰13C = -25,12. Os leitões foram aleatoriamente distribuídos em duas dietas: uma sem suplementação de glutamina; e outra suplementada com 1% de glutamina. Aos 0; 1; 1,5; 2; 2,5; 3; 3,5; 4; 4,5; 5; 5,5; 8; 11; 15, 20; 29 e 46 dias pós-desmame, dois leitões de cada dieta foram abatidos para coleta de amostras da mucosa intestinal, que foram analisadas quanto à composição isotópica de d‰13C e mensurada a velocidade de substituição do carbono no tempo. Os valores da meia-vida do carbono para a mucosa intestinal foram de 6,0 e 3,5 dias para as dietas controle e com glutamina, respectivamente. A glutamina acelerou a velocidade de substituição do carbono na mucosa intestinal, evidenciando sua ação benéfica na recuperação da estrutura do intestino após o desmame.An experiment was carried out to evaluate the influence of glutamine on the carbon turnover in the intestinal mucosa of weaned piglets. Nine matrices received diets predominantly composed by photosintetic cycle C4 plants during the gestation (d‰13C = -17.12 and lactation (d‰13C = -19.26. The piglets were weaned at 21 days of age, and 68 animals were fed rations composed by photosintetic cycle C3 plants (d‰13C = -25.12. The piglets were distributed at random in two treatments: one diet without glutamine supplementation and the other diet supplemented with 1% of glutamine. On days 0; 1; 1.5; 2; 2.5; 3; 3.5; 4; 4.5; 5; 5.5; 8; 11; 15, 20; 29 and 46 after weaning, two piglets from each diet were slaughtered for collection of samples

  2. Analise dos impactos tecnico-economicos da utilização do piche de alcatrão de eucalipto como precursor de fibras de carbono ativadas

    OpenAIRE

    2000-01-01

    Resumo: Apresenta-se um estudo do processo de obtenção de fibras de carbono ativadas a partir do piche vegetal com objetivo de aumentar valor agregado de sub-produtos da produção de carvão vegetal, abrindo desta forma, a possibilidade de novos mercados para esses sub-produtos. Para tanto, analisou-se através de séries históricas, a evolução da produção de carvão vegetal, sua demanda e oferta, assim como os principais setores consumidores, destacando-se dentre outros o setor industrial. Atravé...

  3. Diseño de polvos de molde para colada continua de slabs de aceros bajo carbono

    Directory of Open Access Journals (Sweden)

    Cruz-Ramírez, A.

    2004-02-01

    Full Text Available Commercial fluxes were characterized by laboratory tests, and their original properties were changed with additions of chemical reagents in order to establish criteria and design strategies to produce new fluxes. The characterization of the commercial fluxes reveals that they are produced by simple mechanical blend of minerals, using feldspars and clays as base materials, containing SiO2, Al2O3, Na2 O and in less quantity K2O, MgO, Fe2 O3and MnO; limestone as the main source of CaO, fluorspar (CaF2 used to control the viscosity and graphite as carbon source. Melting-solidification tests revealed melting and fluidity temperatures and the existence of abundant mineralogical phases formed during the flux solidification. Some important mineralogical compounds are the nepheline (NaAlSiO4 and cuspidine (Ca4Si2O7F2; these species have a direct influence on the heat transfer phenomena from strand to mold and therefore on the phase transformations and the shrinkage of the steel.

    A partir de la caracterización de polvos comerciales mediante pruebas de laboratorio y la modificación de sus propiedades mediante adiciones de compuestos químicos, se identificaron y desarrollaron criterios y estrategias de diseño que sirvieron de base para elaborar nuevos polvos. La caracterización de los polvos comerciales indica que se fabrican por simple mezcla mecánica de minerales, utilizando feldespatos y arcillas como materiales base, que contienen SiO2, Al2O3, Na2 O y, en menor proporción, K 2O, MgO, Fe2 O3 y MnO, caliza como fuente principal de CaO, fluorita (CaF2 como fluidificante y grafito como fuente de carbono. Mediante pruebas de fusión-solidificación se determinaron las temperaturas de fusión y fluidez de los polvos y

  4. Isótopos estáveis e produção de bebidas: de onde vem o carbono que consumimos?

    Directory of Open Access Journals (Sweden)

    Ana Cristina B. Oliveira

    2002-12-01

    Full Text Available A composição isotópica do carbono (delta13C foi utilizada na determinação da origem botânica (C3 x C4 de amostras de café, vinho, cerveja e vodka, de diferentes marcas e procedências, comercializadas no Brasil. Dentre as marcas de café analisadas, apenas uma apresentou um elevado percentual de plantas C4 em sua composição, evidenciado pelo valor de delta13C (-16,2‰. Os valores de delta13C das amostras de vinhos brasileiros, variaram entre -25,1 e -17,1‰, indicando a presença de carbono de origem C4 nas amostras que tiveram os maiores valores de delta13C. Duas marcas de vinhos importados, por sua vez, apresentaram delta13C característico de planta C3 (-27,1 e -26,3‰. Os valores de delta13C das vodkas importadas variaram entre -26,4 e -23,9‰, e as brasileiras entre -12,8 e -11,8‰, excetuando-se uma marca que apresentou valor -23,1‰. As marcas de cervejas importadas, em sua maioria, apresentaram valores mais negativos (-27,3 a -20,7‰ que as nacionais (-25,9 a -18,4‰. Estes resultados evidenciam a eficiência desta metodologia na determinação da origem do C e percentual de mistura destas bebidas.

  5. Isótopos estáveis e produção de bebidas: de onde vem o carbono que consumimos?

    Directory of Open Access Journals (Sweden)

    Oliveira Ana Cristina B.

    2002-01-01

    Full Text Available A composição isotópica do carbono (delta13C foi utilizada na determinação da origem botânica (C3 x C4 de amostras de café, vinho, cerveja e vodka, de diferentes marcas e procedências, comercializadas no Brasil. Dentre as marcas de café analisadas, apenas uma apresentou um elevado percentual de plantas C4 em sua composição, evidenciado pelo valor de delta13C (-16,2‰. Os valores de delta13C das amostras de vinhos brasileiros, variaram entre -25,1 e -17,1‰, indicando a presença de carbono de origem C4 nas amostras que tiveram os maiores valores de delta13C. Duas marcas de vinhos importados, por sua vez, apresentaram delta13C característico de planta C3 (-27,1 e -26,3‰. Os valores de delta13C das vodkas importadas variaram entre -26,4 e -23,9‰, e as brasileiras entre -12,8 e -11,8‰, excetuando-se uma marca que apresentou valor -23,1‰. As marcas de cervejas importadas, em sua maioria, apresentaram valores mais negativos (-27,3 a -20,7‰ que as nacionais (-25,9 a -18,4‰. Estes resultados evidenciam a eficiência desta metodologia na determinação da origem do C e percentual de mistura destas bebidas.

  6. Metabolismo de los hidratos de carbono en el síndrome de ovario poliquístico Metabolism of Carbohydrates in the Polycystic Ovary Syndrome

    Directory of Open Access Journals (Sweden)

    Melina Sabán

    2012-06-01

    Full Text Available El síndrome de ovario poliquístico (SOP es una entidad fisiopatológica compleja caracterizada por la presencia de: Irregularidades menstruales, hirsutismo, acné, obesidad y resistencia a la insulina. La frecuencia de intolerancia a los hidratos de carbono y diabetes mellitus en pacientes con SOP es del 30-40 % y 5-10 %; respectivamente. En pacientes con SOP el riesgo de desarrollar diabetes mellitus tipo 2 es mayor que el de la población general. Se debe destacar que la tolerancia a la glucosa alterada, representa un factor de riesgo importante para el desarrollo de diabetes y enfermedad cardiovascular. El método más sensible para detectar tolerancia a la glucosa alterada, en mujeres con SOP, es la prueba de tolerancia oral a la glucosa. De esta manera, el objetivo fue analizar los distintos mecanismos implicados en el SOP y las alteraciones del metabolismo de los hidratos carbono. Los autores declaran no poseer conflictos de interés.Polycystic ovary syndrome (PCO is a complex pathophysiological entity characterized by the presence of: menstrual irregularities, hirsutism, acne, obesity and insulin resistance. The estimated frequency of intolerance to carbohydrates and diabetes mellitus in patients with PCOS is 30-40 % and 5-10 %, respectively. In patients with PCO, the risk of developing type 2 diabetes mellitus is higher than in the general population. It should be noted that glucose intolerance is a major risk factor for developing diabetes and cardiovascular disease. The most sensitive test to detect glucose intolerance in women with PCO is the oral glucose tolerance test. Thus, the aim of this study was to analyze the different mechanisms involved in PCO and disorders of carbohydrate metabolism. No financial conflicts of interest exist.

  7. EVALUACIÓN DE PARÁMETROS DE CALIDAD PARA LA DETERMINACIÓN DE CARBONO ORGÁNICO EN SUELOS

    Directory of Open Access Journals (Sweden)

    johnbrynner García Galvis

    2008-03-01

    Full Text Available En el estudio de la cuantificación de carbono orgánico en suelos por el método Walkley-Black se compararon dos técnicas de análisis (colorimetría y volumetría con el fin de evaluar los parámetros de calidad y así indicar la técnica más conveniente para implementarla en el análisis de suelos. Se determinó un intervalo lineal de 5 a 50 mg/mL de sacarosa a una longitud de onda de máxima absorción de 585 nm del ácido crómico reducido. Al comparar los dos métodos de cuantificación se encontraron evidencias de errores sistemáticos en el método volumétrico para los niveles evaluados (alto, medio y bajo de concentración de sacarosa, mientras que por el método colorimétrico la cuantificación fue más exacta y además los valores de desviación estándar y coeficientes de variación fueron menores, parámetros que lo catalogan como el método más preciso. Además, para tener un mayor soporte analítico se implementaron las metodologías en diferentes tipos de suelos; los resultados indicaron que el método colorimétrico para la determinación de carbono orgánico en suelos presentó menores costos y número de reactivos por análisis, y a su vez fue el que ofreció la mejor repetibilidad.

  8. Labile carbon pools and biological activity in volcanic soils of the Canary Islands Fracciones de carbono orgánico lábil y actividad biológica en suelos de origen volcánico de las Islas Canarias Frações de carbono orgânico lábil e actividade biológica em solos de origem vulcânica das Ilhas Canárias

    Directory of Open Access Journals (Sweden)

    Cecilia María Armas Herrera

    2013-03-01

    (0.77 g kg-1, which represents an SOC pool of low bioavailability, was protected by its adsorption to allophane in silandic Andosols.La medida de la susceptibilidad del carbono orgánico del suelo (SOC a la mineralización es esencial para predecir la respuesta a corto plazo de los reservorios biosféricos de carbono a los cambios en las condiciones ambientales. En este trabajo abordamos el estudio del SOC lábil (fácilmente mineralizable en suelos volcánicos, donde la biodisponibilidad del SOC se ve característicamente afectada por mecanismos de estabilización físico-química propios de estos suelos. Con este fin seleccionamos diez suelos representativos (sobre todo Andosoles de los principales hábitats naturales (matorral xerofítico, monteverde y pinar en las Islas Canarias, un archipiélago de origen volcánico. Durante dos años medimos diversas fracciones de SOC a las que se atribuye un distinto grado de biodisponibilidad: carbono soluble en agua en muestras frescas de suelo (WSC y en el extracto saturado (WSCse, carbono extraíble en agua caliente (HWC, carbono extraíble con sulfato potásico (PSC, carbono ligado a la biomasa microbiana (MBC, carbono orgánico particulado (POC, carbono de sustancias húmicas (HSC, y carbono orgánico total (TOC, y realizamos ensayos de incubación de las emisiones de CO2. Relacionamos estas medidas con los posibles aportes de carbono procedentes de la hojarasca y las raíces, y la actividad de enzimas hidrolíticas (CM-celulasa, ?-D-glucosidasa, y deshidrogenasa implicadas en el ciclado del carbono. La medida in vitro de la mineralización en ensayos cortos (10 días se ajustó a un modelo cinético simple de primer orden, un procedimiento sencillo que nos permitió obtener no sólo una estimación del SOC más inmediatamente mineralizable, sino también de la heterogeneidad de los sustratos consumidos durante la incubación. Los suelos volcánicos investigados mostraron una gran riqueza de SOC lábil, en los que

  9. Valoración Económica del Manglar por el Almacenamiento de Carbono, Ciénaga Grande de Santa Marta

    Directory of Open Access Journals (Sweden)

    Arnold De la Peña

    2014-01-01

    Full Text Available La Ciénaga Grande de Santa Marta (CGSM genera diferentes bienes y servicios ambientales, por ejemplo, sumidero de carbono, hábitat de flora y fauna, despensa de alimentos y materias primas, entre otros. Se presenta una aproximación a la cuantificación monetaria del servicio de almacenamiento de carbono, con el fin de establecer información base para las decisiones de su uso. Lo anterior se hizo con base en muestreo de campo de 15 árboles de manglar y en mediciones realizadas en cuatro estaciones de monitoreo de la CGSM (Caño Grande, Rinconada, Aguas Negras y Luna por INVEMAR (2008. Para tal fin, se estimó la biomasa aérea total, las existencias de carbono y de dióxido de carbono equivalente (CO2e discriminada por especie y zona. Los resultados indican que en términos relativos el bosque de manglar de la CGSM puede almacenar entre 6,9 (la Luna y 45,7 (Rinconada t C ha-1. La valoración monetaria se encuentran entre US$ 87,76 y 591,41 t CO2e ha-1, según los precios pagados por el Banco Mundial, correspondiente a los Certificados de Emisiones Reducidas (CERs forestales no permanentes. El valor monetario amplia la importancia de iniciar un proceso que permita incorporar estos beneficios económicos a los actuales mecanismos de mercado y contribuyan a los esfuerzos locales de conservación.Palabras Clave: Manglar; almacenamiento de carbono; biomasa aérea; dióxido de carbono equivalente y valoración económica. Economic Valuation of Mangrove for the Carbon Storage in the Ciénaga Grande de Santa MartaAbstractThe Cienaga Grande de Santa Marta (CGSM Generate Different Environmental goods and services, for instance, carbon sink, habitat for flora and fauna, stocks of foods and raw materials, etc. This paper presents an attempt to value in monetary terms the service of carbon storage, with the aim to establish inputs for the decisions process of used. This paper presents an Attempt to Terms Monetary value in the service of carbon storage

  10. A Sensor Observation Service Extension for the GeoServices REST API

    Science.gov (United States)

    Bröring, A.; Sankaran, S.; Jirka, S.; Wytzisk, A.

    2012-04-01

    This presentation demonstrates an extension for the GeoServices REST API implemented on the ArcGIS server platform to provide near real time environmental data. The software has been developed by 52° North in context of a project with the European Environment Agency (EEA). The EEA collects huge amounts of environmental data from various agencies of the different EU member states and needs to redistribute them to decision makers as well as the general public. The key element of EEA's strategy to distribute these data is the compliancy to open standards. Relevant standards are developed and governed by the Open Geospatial Consortium (OGC); on the one hand the GeoServices REST API, currently making its way through the standardization process, and on the other hand the Sensor Observation Service (SOS), a web service interface specialized for the retrieval of sensor observations. In this work, we have combined these two standards. Therefore, we have extended the GeoServices REST API to support the provision of sensor observations, by resembling the functionality of the SOS 2.0 interface. The defined extension for the GeoServices REST API offers a simple request and response encoding of the SOS 2.0. It is aligned with the abstract service model of the SOS 2.0 specification, but provides a new implementation of this standard which complies to the GeoServices REST API. The SOS extension allows querying of observations, metadata about sensors, as well as descriptions of features observed by the sensors. These data sets are made available as resources. Either all available resource instances can be queried or the resources can be filtered with powerful query operations. The software is implemented as a so-called Server Object Extension, or short SOE, for ArcGIS Server 10.1. This presentation will demonstrate the SOE deployed for air quality observations measured from a network of over 1.500 stations all across Europe. In the coming weeks, the SOS Extension will be further

  11. Variações nos teores de carbono orgânico em função do desmatamento e revegetação natural do solo

    Directory of Open Access Journals (Sweden)

    Sidinei Leandro Klöckner Stürmer

    2011-06-01

    Full Text Available A flutuação no conteúdo de matéria orgânica do solo é severamente afetada pelo uso e manejo do solo. Em solos física e quimicamente frágeis a destruição da vegetação nativa pode levar a diminuição drástica do estoque de carbono. No entanto, solos jovens que apresentam alta resiliência, quando manejados adequadamente, podem recuperar facilmente os valores originais de carbono. O objetivo deste trabalho foi quantificar os teores de carbono orgânico de um Neossolo e um Chernossolo em decorrência de seu uso, em especial após o desmatamento e revegetação natural. Coletaram-se amostras de duas camadas (0-5 e 5-15 cm em dois solos (Neossolo e Chernossolo ocorrentes numa pequena bacia hidrográfica com relevo fortemente ondulado, com quatro condições de uso (mata nativa, lavoura nova, lavoura velha e revegetação com capoeira. Avaliaram-se a distribuição granulométrica, a densidade do solo e os teores de carbono orgânico. Os dados foram submetidos à análise estatística considerando um delineamento inteiramente casualizado, num esquema trifatorial (tipos de solos, tipos de usos e camadas amostradas. O estoque de carbono do solo diminuiu após o desmatamento para a inastalação de culturas anuais com baixa adição de resíduos e revolvimento intenso do solo. A revegetação natural das áreas degradadas pelo cultivo convencional recuperou rapidamente o estoque de carbono dos solos, mesmo permanecendo as impressões herdadas da erosão (menor teor de argila e da aplicação de fertilizantes e corretivos (menor acidez potencial e maior disponibilidade de fósforo e potássio.

  12. Efeito da glutamina sobre o turnover do carbono (d13C de músculos e vísceras de leitões desmamados: glutamina e turnover de carbono tecidual = Effect of glutamine on carbon (d13C turnover in the muscles and viscera of weaned piglets

    Directory of Open Access Journals (Sweden)

    Fabiana Ribeiro Caldara

    2008-07-01

    Full Text Available O estudo foi conduzido para verificar a influência da glutamina no turnover do carbono em tecidos de leitões. Nove porcas foram cobertas e receberam dietas compostas predominantemente por grãos de plantas do ciclo fotossintético C4 durante gestação e lactação. Aos 21 dias de idade, 48 leitões foram distribuídos aleatoriamente nos tratamentos: T1 = dieta C3, sem suplementação de glutamina, e T2 = dieta C3, suplementada com 1% de glutamina. Nos dias 0, 1, 2, 3, 4, 5, 8, 11, 15, 20, 29 e 46 pós-desmame, foram abatidos dois leitões/tratamento. Amostras dos músculos Psoas major e Masseter, fígado e pâncreas foram coletadas e analisadas quanto à composição em d‰13C e mensurada a substituição do carbono em função do tempo. A glutamina acelerou a substituição do carbono em ambos os músculos, como observado pelos valores de meia-vida (T destes tecidos (T = 51,4 e 21,7 dias para Masseter e 31,5 e 20,3 dias para Psoas major, nos tratamentos sem e com suplementação de glutamina, respectivamente. Os valores de meia-vida do carbono das vísceras indicam que esse aminoácido também acelerou o turnover do carbono nestes órgãos. Os resultados indicam estímulo anabólico da glutamina sobre os tecidos avaliados.The study was carried out to verify the influence of glutamineon carbon turnover in the muscles and viscera of piglets. Nine sows were bred and received diets predominantly composed by grains of C4 photosynthetic cycle plants during gestation and lactation. The piglets were weaned at 21 days of age, and 48 animals were distributed at random in two treatments: T1 = C3 diet, without glutamine supplementation; and T2 = C3 diet, supplemented with 1% glutamine. On days 0, 1, 2, 3, 4, 5, 8, 11, 15, 20, 29 and 46 postweaning, two piglets per treatment were slaughtered. Samples of the Psoas major and Masseter muscles, liver and pancreas were collected and analyzed for d‰13C composition, and carbon turnover was measured as a

  13. In-Depth N-Glycosylation Reveals Species-Specific Modifications and Functions of the Royal Jelly Protein from Western (Apis mellifera) and Eastern Honeybees (Apis cerana).

    Science.gov (United States)

    Feng, Mao; Fang, Yu; Han, Bin; Xu, Xiang; Fan, Pei; Hao, Yue; Qi, Yuping; Hu, Han; Huo, Xinmei; Meng, Lifeng; Wu, Bin; Li, Jianke

    2015-12-04

    Royal jelly (RJ), secreted by honeybee workers, plays diverse roles as nutrients and defense agents for honeybee biology and human health. Despite being reported to be glycoproteins, the glycosylation characterization and functionality of RJ proteins in different honeybee species are largely unknown. An in-depth N-glycoproteome analysis and functional assay of RJ produced by Apis mellifera lingustica (Aml) and Apis cerana cerana (Acc) were conducted. RJ produced by Aml yielded 80 nonredundant N-glycoproteins carrying 190 glycosites, of which 23 novel proteins harboring 35 glycosites were identified. For Acc, all 43 proteins glycosylated at 138 glycosites were reported for the first time. Proteins with distinct N-glycoproteomic characteristics in terms of glycoprotein species, number of N-glycosylated sites, glycosylation motif, abundance level of glycoproteins, and N-glycosites were observed in this two RJ samples. The fact that the low inhibitory efficiency of N-glycosylated major royal jelly protein 2 (MRJP2) against Paenibacillus larvae (P. larvae) and the absence of antibacterial related glycosylated apidaecin, hymenoptaecin, and peritrophic matrix in the Aml RJ compared to Acc reveal the mechanism for why the Aml larvae are susceptible to P. larvae, the causative agent of a fatal brood disease (American foulbrood, AFB). The observed antihypertension activity of N-glycosylated MRJP1 in two RJ samples and a stronger activity found in Acc than in Aml reveal that specific RJ protein and modification are potentially useful for the treatment of hypertensive disease for humans. Our data gain novel understanding that the western and eastern bees have evolved species-specific strategies of glycosylation to fine-tune protein activity for optimizing molecular function as nutrients and immune agents for the good of honeybee and influence on the health promoting activity for human as well. This serves as a valuable resource for the targeted probing of the biological

  14. Effects of Microsatellite Genetic Polymorphisms of Apis mellifera ligustica on Nutritional Crossbreed between Apis cerana cerana and Apis mellifera ligustica%中蜂与意蜂营养杂交对意蜂微卫星遗传多态性的影响

    Institute of Scientific and Technical Information of China (English)

    何旭江; 汪志平; 秦秋红; 吴小波; 陈利华

    2011-01-01

    In this paper,we breed hybridizing queen of the Jiangshan honey bee No. 2 and French Apis mellifera ligustica through the technology of artificially feeding royal jelly of Apis cerana cerana, and then the genetic polymorphisms of microsatellite of the workers were measured. The workers were from the Jiangshan honey bee No. 2 colonies, French Apis mellifera ligustica colonies, local Apis cerana cerana colonies, the 1 hybridizing offspring as well as the 4 consecutive hybridizing offspring of nutritional crossbreeding French Apis. merllifera. L queen and the Jiangshan honey bee No. 2 drone colonies. The results showed that the genetic distance of parents and hybridizing offspring was varied, and the unique DNA bands of Apis cerana cerana and Apis melli fera ligustica were shifted.%通过人工添加中华蜜蜂王浆技术来培育江山2号与法国意蜂的杂交蜂王,并测定江山2号、法国意蜂、中华蜜蜂、营养杂交子1代和子4代工蜂的微卫星遗传多态性.结果表明,经过营养杂交,亲本蜜蜂与营养杂交子代的遗传距离发生明显的变化,中华蜜蜂和意大利蜜蜂的特有DNA条带发生了转移.说明通过蜂种之间的营养杂交可以改变其微卫星多态性.

  15. OXIDACIÓN POR VÍA HÚMEDA CATALÍTICA DE EFLUENTES INDUSTRIALES EMPLEANDO UN CATALIZADOR DE Pt SOPORTADO EN NANOTUBOS DE CARBONO DE PARED MÚLTIPLE

    Directory of Open Access Journals (Sweden)

    Gabriel Ovejero

    2011-01-01

    Full Text Available En el presente trabajo se ha estudiado la efectividad de la oxidación por vía húmeda catalítica para tratar aguas residuales industriales en un reactor por lote. Para ello se han realizado ensayos con un contaminante modelo, el colorante básico Amarillo Directo 11 empleando como catalizador platino soportado en nanotubos de carbono de pared múltiple (Pt/MWNT. Así mismo se ha realizado el tratamiento de dos efluentes industriales. Los resultados muestran tanto la alta efectividad del tratamiento en presencia del catalizador, como una importante disminución del carbono orgánico total y de la toxicidad en el efluente final. Se concluye que el proceso se ha demostrado eficaz tanto para el tratamiento del colorante básico ensayado, como en los dos efluentes residuales industriales.

  16. PRODUCCIÓN DE NANOPARTÍCULAS DEL SISTEMA Al‐Cu‐Fe POR MOLIENDA MECÁNICA PARA SINTETIZAR NANOESTRUCTURAS DE CARBONO Y PRODUCCIÓN DE HIDRÓGENO

    OpenAIRE

    Patiño Carachure, Cristobal

    2012-01-01

    En este trabajo, se estudia la síntesis de nanoestructuras de carbono empleando como un nuevo método, la molienda mecánica de nanopartículas del sistema Al-Cu-Fe en un medio de etanol. Siendo éste una fuente de carbono. Por otro lado, también es evaluada la producción de hidrógeno como subproducto de la reacción de fragilización inducida por la molienda mecánica de bolas en un medio húmedo de las aleaciones, cuya composición poseen una cantidad de aluminio en mayor proporción. ...

  17. COMPORTAMIENTO HIDRODINÁMICO Y ABSORCIÓN DE DIÓXIDO DE CARBONO MEDIANTE REACCIÓN QUÍMICA CON GLUCOSAMINA EN UN REACTOR AIR-LIFT

    Directory of Open Access Journals (Sweden)

    Alicia García-Abuín

    2010-01-01

    Full Text Available En el presente trabajo se ha estudiado el comportamiento de disoluciones acuosas de glucosamina como absorbente para la captura de dióxido de carbono, empleando un reactor “air-lift”. Los resultados experimentales indican que este reactivo (glucosamina muestra un comportamiento similar al observado para otras disoluciones acuosas de aminas ampliamente utilizadas para la captura de dióxido de carbono, en relación a la velocidad a la cual se produce la absorción. El valor de la velocidad de transferencia de masa ha sido determinado, así como el efecto de distintas condiciones de operación sobre el valor de este parámetro y del área interfacial gas-líquido, tales como concentración de amina, pH o caudal de gas alimentado.

  18. JUPITER: Joint Universal Parameter IdenTification and Evaluation of Reliability - An Application Programming Interface (API) for Model Analysis

    Science.gov (United States)

    Banta, Edward R.; Poeter, Eileen P.; Doherty, John E.; Hill, Mary C.

    2006-01-01

    The Joint Universal Parameter IdenTification and Evaluation of Reliability Application Programming Interface (JUPITER API) improves the computer programming resources available to those developing applications (computer programs) for model analysis. The JUPITER API consists of eleven Fortran-90 modules that provide for encapsulation of data and operations on that data. Each module contains one or more entities: data, data types, subroutines, functions, and generic interfaces. The modules do not constitute computer programs themselves; instead, they are used to construct computer programs. Such computer programs are called applications of the API. The API provides common modeling operations for use by a variety of computer applications. The models being analyzed are referred to here as process models, and may, for example, represent the physics, chemistry, and(or) biology of a field or laboratory system. Process models commonly are constructed using published models such as MODFLOW (Harbaugh et al., 2000; Harbaugh, 2005), MT3DMS (Zheng and Wang, 1996), HSPF (Bicknell et al., 1997), PRMS (Leavesley and Stannard, 1995), and many others. The process model may be accessed by a JUPITER API application as an external program, or it may be implemented as a subroutine within a JUPITER API application . In either case, execution of the model takes place in a framework designed by the application programmer. This framework can be designed to take advantage of any parallel processing capabilities possessed by the process model, as well as the parallel-processing capabilities of the JUPITER API. Model analyses for which the JUPITER API could be useful include, for example: * Compare model results to observed values to determine how well the model reproduces system processes and characteristics. * Use sensitivity analysis to determine the information provided by observations to parameters and predictions of interest. * Determine the additional data needed to improve selected

  19. Respiración del suelo como herramienta para evaluar calidad de fondos en acuicultura. i. desarrollo de un protocolo estándar para medir dióxido de Carbono

    OpenAIRE

    2003-01-01

    Respiración del suelo como herramienta para evaluar calidad de fondos en acuicultura. I. Desarrollo de un protocolo estándar para medir dióxido de carbono La calidad de los suelos es determinada principalmente por métodos químicos tales como: contenido de materia orgánica (MO), azufre, elementos minerales, potencial de hidrógeno (pH) y potencial redox, entre otros.

  20. Loop-mediated isothermal amplification (LAMP) assays for rapid detection and differentiation of Nosema apis and N. ceranae in honeybees.

    Science.gov (United States)

    Ptaszyńska, Aneta A; Borsuk, Grzegorz; Woźniakowski, Grzegorz; Gnat, Sebastian; Małek, Wanda

    2014-08-01

    Nosemosis is a contagious disease of honeybees (Apis mellifera) manifested by increased winter mortality, poor spring build-up and even the total extinction of infected bee colonies. In this paper, loop-mediated isothermal amplifications (LAMP) were used for the first time to identify and differentiate N. apis and N. ceranae, the causative agents of nosemosis. LAMP assays were performed at a constant temperature of 60 °C using two sets of six species-specific primers, recognising eight distinct fragments of 16S rDNA gene and GspSSD polymerase with strand displacement activity. The optimal time for LAMP and its Nosema species sensitivity and specificity were assessed. LAMP only required 30 min for robust identification of the amplicons. Ten-fold serial dilutions of total DNA isolated from bees infected with microsporidia were used to determine the detection limit of N. apis and N. ceranae DNAs by LAMP and standard PCR assays. LAMP appeared to be 10(3) -fold more sensitive than a standard PCR in detecting N. apis and N. ceranae. LAMP methods developed by us are highly Nosema species specific and allow to identify and differentiate N. apis and N. ceranae.