WorldWideScience

Sample records for carbon 10 beams

  1. Ion beam induced charge collection (IBICC) from integrated circuit test structures using a 10 MeV carbon microbeam

    Energy Technology Data Exchange (ETDEWEB)

    Guo, B.N.; Bouanani, M.E.; Duggan, J.L.; McDaniel, F.D. [Ion Beam Modification and Analysis Laboratory, Department of Physics, University of North Texas, Denton, Texas 76203 (United States); Doyle, B.L.; Walsh, D.S. [Ion Beam Materials Research Laboratory, Sandia National Laboratories, MS 1056, PO Box 5800, Albuquerque, New Mexico 87185 (United States)] Aton, T.J. [Silicon Technology Development, Texas Instruments Inc., PO Box 650311, MS 3704, Dallas, Texas 75265 (United States)

    1999-06-01

    As feature sizes of Integrated Circuits (ICs) continue to shrink, the sensitivity of these devices, particularly SRAMs and DRAMs, to natural radiation is increasing. In this paper, the Ion Beam Induced Charge Collection (IBICC) technique is utilized to simulate neutron-induced Si recoil effects in ICs. The IBICC measurements, conducted at the Sandia National Laboratories, employed a 10 MeV carbon microbeam with 1{mu}m diameter spot to scan test structures on specifically designed ICs. With the aid of IC layout information, an analysis of the charge collection efficiency from different test areas is presented. {copyright} {ital 1999 American Institute of Physics.}

  2. Ion Beam Induced Charge Collection (IBICC) from Integrated Circuit Test Structures Using a 10 MeV Carbon Microbeam

    Energy Technology Data Exchange (ETDEWEB)

    Aton, T.J.; Doyle, B.L.; Duggan, J.L.; El Bouanani, M.; Guo, B.N.; McDaniel, F.D.; Renfrow, S.N.; Walsh, D.S.

    1998-11-18

    As future sizes of Integrated Circuits (ICs) continue to shrink the sensitivity of these devices, particularly SRAMs and DRAMs, to natural radiation is increasing. In this paper, the Ion Beam Induced Charge Collection (IBICC) technique is utilized to simulate neutron-induced Si recoil effects in ICS. The IBICC measurements, conducted at the Sandia National Laboratories employed a 10 MeV carbon microbeam with 1pm diameter spot to scan test structures on specifically designed ICS. With the aid of layout information, an analysis of the charge collection efficiency from different test areas is presented. In the present work a 10 MeV Carbon high-resolution microbeam was used to demonstrate the differential charge collection efficiency in ICS with the aid of the IC design Information. When ions strike outside the FET, the charge was only measured on the outer ring, and decreased with strike distance from this diode. When ions directly strike the inner and ring diodes, the collected charge was localized to these diodes. The charge for ions striking the gate region was shared between the inner and ring diodes. I The IBICC measurements directly confirmed the interpretations made in the earlier work.

  3. Carbon beam dosimetry using VIP polymer gel and MRI

    DEFF Research Database (Denmark)

    Kantemiris, I; Petrokokkinos, L; Angelopoulos, A;

    2009-01-01

    VIP polymer gel dosimeter was used for Carbon ion beam dosimetry using a 150 MeV/n beam with 10 Gy plateau dose and a SOBP irradiation scheme with 5 Gy Bragg peak dose. The results show a decrease by 8 mm in the expected from Monte Carlo simulation range in water, suggesting that the dosimeter...

  4. Plasma beam discharge in carbon dioxide

    International Nuclear Information System (INIS)

    The paper deals with the dissociation of carbon dioxide in nonequilibrium plasma of a stationary plasma-beam discharge. Experimental results of spectroscopic and probe measurements of plasma parameters are given. Moreover, a mass-spectrometric analysis of gaseous products of the chemical reactions is presented. In addition the measurement of the deposition rate of solid products by means of a quartz oscillator is described. The results show that plasma beam discharge is an effective tool for inducing plasma-chemical reactions. (author)

  5. Carbon beams, production and acceleration

    International Nuclear Information System (INIS)

    Installation, test and working conditions of a new negative-ion facility of the Salazar EN tandem are briefly described. Carbon is the material used for the test and the heavy ion stripping phenomenon is reviewed. (author)

  6. Electron beam processing of carbon fibre reinforced braided composites beams

    International Nuclear Information System (INIS)

    Complete text of publication follows. In this paper the possibility of producing a new type carbon fiber reinforced composite is examined by applying braiding, a well-known process of textile technology. The appearance of the new Hungarian carbon fiber with excellent mechanical properties in the market enables the development of newer type carbon fiber reinforced composites in the continuously widening range of engineering applications. Advanced hollow profiles, pipes and other composite products can be manufactured in continuous operation. A new way of composite production of this kind is the manufacturing of reinforcing structure by braiding technology producing a composite with sufficient mechanical properties from this cross directional fabric-like textile structure by impregnation. This manufacturing process can complete the variety of hollow products serving the same purpose as pultrusion or filament winding. This way a profile type framework element with a hollow cross section is manufactured having favorable mechanical properties. Owing to its small mass and high specific strength this product can be applied in dynamically loaded structures e.g. in the automotive industry. For crosslinking of the matrix the method of high-speed electron beam curing has been examined in order to reach continuous operation. The field of use and application of carbon fiber braided structures has a great chance especially in machine engineering and in the automotive industry. The main reason for this is that braiding processes are capable of producing structures having good mechanical properties at a low processing price. The mass of the composite load-bearing structure produced this way is one fifth of the steel product having similar geometry, and its specific mechanical properties are nearly as good as that of the most commonly applied semiproduct and structural component, the welded steel profile

  7. Intensive irradiation of carbon nanotubes by Si ion beam

    Institute of Scientific and Technical Information of China (English)

    NI Zhichun; LI Qintao; YAN Long; GONG Jinlong; ZHU Dezhang; ZHU Zhiyuan

    2007-01-01

    Multi-walled carbon nanotubes were irradiated with 40 keV Si ion beam to a dose of 1×1017 cm-2. The multiple-way carbon nanowire junctions and the Si doping in carbon nanowires were realized. Moreover, the formation processes of carbon nanowire junctions and the corresponding mechanism were studied.

  8. Shunting arc plasma source for pure carbon ion beam

    Energy Technology Data Exchange (ETDEWEB)

    Koguchi, H.; Sakakita, H.; Kiyama, S.; Shimada, T.; Sato, Y.; Hirano, Y. [Energy Technology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Umezono, Tsukuba, Ibaraki 305-8568 (Japan)

    2012-02-15

    A plasma source is developed using a coaxial shunting arc plasma gun to extract a pure carbon ion beam. The pure carbon ion beam is a new type of deposition system for diamond and other carbon materials. Our plasma device generates pure carbon plasma from solid-state carbon material without using a hydrocarbon gas such as methane gas, and the plasma does not contain any hydrogen. The ion saturation current of the discharge measured by a double probe is about 0.2 mA/mm{sup 2} at the peak of the pulse.

  9. Shunting arc plasma source for pure carbon ion beam.

    Science.gov (United States)

    Koguchi, H; Sakakita, H; Kiyama, S; Shimada, T; Sato, Y; Hirano, Y

    2012-02-01

    A plasma source is developed using a coaxial shunting arc plasma gun to extract a pure carbon ion beam. The pure carbon ion beam is a new type of deposition system for diamond and other carbon materials. Our plasma device generates pure carbon plasma from solid-state carbon material without using a hydrocarbon gas such as methane gas, and the plasma does not contain any hydrogen. The ion saturation current of the discharge measured by a double probe is about 0.2 mA∕mm(2) at the peak of the pulse.

  10. Shunting arc plasma source for pure carbon ion beam.

    Science.gov (United States)

    Koguchi, H; Sakakita, H; Kiyama, S; Shimada, T; Sato, Y; Hirano, Y

    2012-02-01

    A plasma source is developed using a coaxial shunting arc plasma gun to extract a pure carbon ion beam. The pure carbon ion beam is a new type of deposition system for diamond and other carbon materials. Our plasma device generates pure carbon plasma from solid-state carbon material without using a hydrocarbon gas such as methane gas, and the plasma does not contain any hydrogen. The ion saturation current of the discharge measured by a double probe is about 0.2 mA∕mm(2) at the peak of the pulse. PMID:22380206

  11. 10 MeV Medical Cyclotron Prototype Beam Commissioning

    Institute of Scientific and Technical Information of China (English)

    GUAN; Feng-ping; GE; Tao; YIN; Zhi-guo; SONG; Guo-fang; ZHANG; Tian-jue; JI; Bin; LI; Peng-zhan; CAO; Lei; HOU; Shi-gang; LIU; Geng-shou; WANG; Feng; LEI; Yu; WU; Long-cheng; WEN; Li-peng; LI; Zhen-guo; CUI; Tao; JIA; Xian-lu; YAO; Hong-juan; PAN; Gao-feng; ZHANG; Su-ping; CAI; Hong-ru; XIE; Huai-dong

    2012-01-01

    <正>A 10 MeV medical cyclotron prototype for the production of short-lived isotopes has been developed independently at CIAE with a time span of 2 years. On the inner target, 8 hours stability test has been finished. The extraction beam is 10 MeV with a beam intensity of 100 μA.

  12. Modeling the Biophysical Effects in a Carbon Beam Delivery Line using Monte Carlo Simulation

    CERN Document Server

    Cho, Ilsung; Cho, Sungho; Kim, Eun Ho; Song, Yongkeun; Shin, Jae-ik; Jung, Won-Gyun

    2016-01-01

    Relative biological effectiveness (RBE) plays an important role in designing a uniform dose response for ion beam therapy. In this study the biological effectiveness of a carbon ion beam delivery system was investigated using Monte Carlo simulation. A carbon ion beam delivery line was designed for the Korea Heavy Ion Medical Accelerator (KHIMA) project. The GEANT4 simulation tool kit was used to simulate carbon beam transporting into media. An incident energy carbon ion beam in the range between 220 MeV/u and 290 MeV/u was chosen to generate secondary particles. The microdosimetric-kinetic (MK) model is applied to describe the RBE of 10% survival in human salivary gland (HSG) cells. The RBE weighted dose was estimated as a function of the penetrating depth of the water phantom along the incident beam direction. A biologically photon-equivalent Spread Out Bragg Peak (SOBP) was designed using the RBE weighted absorbed dose. Finally, the RBE of mixed beams was predicted as a function of the water phantom depth.

  13. Modeling the biophysical effects in a carbon beam delivery line by using Monte Carlo simulations

    Science.gov (United States)

    Cho, Ilsung; Yoo, SeungHoon; Cho, Sungho; Kim, Eun Ho; Song, Yongkeun; Shin, Jae-ik; Jung, Won-Gyun

    2016-09-01

    The Relative biological effectiveness (RBE) plays an important role in designing a uniform dose response for ion-beam therapy. In this study, the biological effectiveness of a carbon-ion beam delivery system was investigated using Monte Carlo simulations. A carbon-ion beam delivery line was designed for the Korea Heavy Ion Medical Accelerator (KHIMA) project. The GEANT4 simulation tool kit was used to simulate carbon-ion beam transport into media. An incident energy carbon-ion beam with energy in the range between 220 MeV/u and 290 MeV/u was chosen to generate secondary particles. The microdosimetric-kinetic (MK) model was applied to describe the RBE of 10% survival in human salivary-gland (HSG) cells. The RBE weighted dose was estimated as a function of the penetration depth in the water phantom along the incident beam's direction. A biologically photon-equivalent Spread Out Bragg Peak (SOBP) was designed using the RBE-weighted absorbed dose. Finally, the RBE of mixed beams was predicted as a function of the depth in the water phantom.

  14. Improvement of carbon fiber surface properties using electron beam irradiation

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Carbon fiber-reinforced advance composites have been used for struetural applications, mainly on account of their mechanical properties. The main factor for a good mechanical performance of carbon fiber-reinforced composite is the interfacial interaction between its components, which are carbon fiber and polymeric matrix. The aim of this study is to improve the surface properties of the carbon fiber using ionizing radiation from an electron beam to obtain better adhesion properties in the resultant composite. EB radiation was applied on the carbon fiber itself before preparing test specimens for the mechanical tests. Experimental results showed that EB irradiation improved the tensile strength of carbon fiber samples. The maximum value in tensile strength was reached using doses of about 250kGy. After breakage, the morphology aspect of the tensile specimens prepared with irradiated and non-irradiated carbon fibers were evaluated. SEM micrographs showed modifications on the carbon fiber surface.

  15. Dose Response of Alanine Detectors Irradiated with Carbon Ion Beams

    DEFF Research Database (Denmark)

    Herrmann, Rochus; Jäkel, Oliver; Palmans, Hugo;

    2011-01-01

    . Methods: Alanine detectors have been irradiated with carbon ions with an energy range of 89-400 MeV/u. The relative effectiveness of alanine has been measured in this regime. Pristine and spread out Bragg peak depth-dose curves have been measured with alanine dosimeters. The track-structure based alanine......Purpose: The dose response of the alanine detector shows a dependence on particle energy and type, when irradiated with ion beams. The purpose of this study is to investigate the response behaviour of the alanine detector in clinical carbon ion beams and compare the results with model predictions...... of the detector geometry implemented in the Monte Carlo simulations....

  16. FIDDLING CARBON STRINGS WITH POLARIZED PROTON BEAMS.

    Energy Technology Data Exchange (ETDEWEB)

    HUANG, H.; KURITA, K.

    2006-05-01

    An innovative polarimeter based on proton carbon elastic scattering in the Coulomb Nuclear Interference (CNI) region was first tested in the Brookhaven AGS successfully. CNI Polarimeters were then installed in the AGS and both RHIC rings. The polarimeter consists of ultra-thin carbon targets and silicon strip detectors. The waveform digitizers are used for signal readout, which allows deadtime-less data processing on the fly. Polarimeters are crucial instrumentation for the RHIC spin physics program. This paper summarizes the polarimeter design issues and operation results.

  17. Biological effect of carbon beams on cultured human cells

    International Nuclear Information System (INIS)

    This study was performed to determine the biological effect of carbon beams on 13 human tumor cells, in comparison with 200 KVp X-rays. Carbon beams were generated by the Riken Ring Cyclotron. The RBE (relative biological effectiveness) values were distributed from 1.46 to 2.20 for LET of 20 keV/μm, and 2.29-3.54 for 80 keV/μm. The RBEs were increased in all cell lines as the LET of carbon beams was increased from 20 to 80 keV/μm. There was no significant difference in radiosensitivity between cells from adenocarcinoma and those from squamous cell carcinoma. The relationship between the radiosensitivity of cells to X-rays and RBE was analyzed, but no significant correlation was suggested. Several survival curves of 20-40 keV/μm carbon beam irradiation showed the initial shoulders and the recovery ratios between two split doses were determined. Recovery was observed for LET of 2O keV/μm but not for that of 40 keV/μm. Furthermore, recovery ratios were 1.0-1.8, smaller than those for X-rays (1.5-2.4). (author)

  18. Design Study of a Superconducting Gantry for Carbon Beam Therapy

    CERN Document Server

    Kim, J

    2016-01-01

    This paper describes the design study of a gantry for a carbon beam. The designed gantry is compact such that its size is comparable to the size of the proton gantry. This is possible by introducing superconducting double helical coils for dipole magnets. The gantry optics is designed in such a way that it provides rotation-invariant optics and variable beam size as well as point-to-parallel scanning of a beam. For large-aperture magnet, three-dimensional magnetic field distribution is obtained by invoking a computer code, and a number of particles are tracked by integrating equations of motion numerically together with three-dimensional interpolation. The beam-shape distortion due to the fringe field is reduced to an acceptable level by optimizing the coil windings with the help of genetic algorithm. Higher-order transfer coefficients are calculated and shown to be reduced greatly with appropriate optimization of the coil windings.

  19. Modification and alignment of beam line of 10 MeV RF electron beam accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Barnwal, R; Ghodke, S R; Bhattacharjee, D; Kumar, M; Jayaprakash, D; Chindarkar, A R; Mishra, R L; Kumar, M; P, Dixit K; S, Acharya; Barje, S R; Lawangare, N K; C, Saroj P; Nimje, V T; Chandan, S; Tillu, A R; V, Sharma; Chavan, R B [Accelerator and Pulse Power Division, BARC, Mumbai, India-400085 (India); Dolas, S [Centre for Design and Manufacturing, BARC, Mumbai, India-400085 (India); Kulkarni, S Y [SAMEER, IIT Powai campus, Mumbai, India-400076 (India)], E-mail: rajesh_barc47@indiatimes.com (and others)

    2008-05-01

    A 10 MeV, 10 kW RF industrial Electron linac designed and developed at BARC is installed at the Electron Beam Center Kharghar, Navi Mumbai. The entire RF accelerator assembly consists of Electron gun, RF source, RF linac structure, Beam diagnostic chamber, Drift tube, Scanning magnet, Beam sensing aperture, Scan horn, and is spread over two floors at EBC. The paper discusses in detail about the alignment procedure adopted for the equipments of 10 MeV RF beamline. The complete electron beamline will be maintained under ultra high vacuum of the order of 10-7 torr. The paper discusses about the present problem of alignment, measurement technique of alignment, reason for misalignment, possible ways to solve the problem, equipment used for alignment, supports and arrestors, verification of alignment under vacuum.

  20. Modification & alignment of beam line of 10 MeV RF electron beam accelerator

    Science.gov (United States)

    Barnwal, R.; Ghodke, S. R.; Bhattacharjee, D.; Kumar, M.; Jayaprakash, D.; Chindarkar, A. R.; Mishra, R. L.; Dolas, S.; Kulkarni, S. Y.; Kumar, M.; P, Dixit K.; S, Acharya; Barje, S. R.; Lawangare, N. K.; C, Saroj P.; Nimje, V. T.; Chandan, S.; Tillu, A. R.; V, Sharma; Chavan, R. B.; V, Yadav; P, Roychowdhury; Mittal, K. C.; Chakravarthy, D. P.; Ray, A. K.

    2008-05-01

    A 10 MeV, 10 kW RF industrial Electron linac designed and developed at BARC is installed at the Electron Beam Center Kharghar, Navi Mumbai. The entire RF accelerator assembly consists of Electron gun, RF source, RF linac structure, Beam diagnostic chamber, Drift tube, Scanning magnet, Beam sensing aperture, Scan horn, and is spread over two floors at EBC. The paper discusses in detail about the alignment procedure adopted for the equipments of 10 MeV RF beamline. The complete electron beamline will be maintained under ultra high vacuum of the order of 10-7 torr. The paper discusses about the present problem of alignment, measurement technique of alignment, reason for misalignment, possible ways to solve the problem, equipment used for alignment, supports & arrestors, verification of alignment under vacuum

  1. The Variation of Surface Dose by Beam Spoiler in 10 MV Photon Beam from Linear Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Seong Cheol; Kim, Jun Ho; Lee, Choul Soo [Dept. of Radiation Oncology, Kosin University Gospel Hospital, Busan (Korea, Republic of)

    2006-03-15

    The purpose of this study is to find a optimal beam spoiler condition on the dose distribution near the surface, when treating a squamous cell carcinoma of the head and neck and a lymphatic region with 10 MV photon beam. The use of a optimal spoiler allows delivering high dose to a superficial tumor volume, while maintaining the skin-sparing effect in the area between the surface to the depth of 0.4 cm. The lucite beam spoiler, which were a tissue equivalent, were made and placed between the surface and the photon collimators of linear accelerator. The surface-dose, the dose at the depth of 0.4 cm, and the maximum dose at the dmax were measured with a parallel-plate ionization chamber for 5 x 5 cm to 30 x 30 cm{sup 2} field sizes using lucite spoilers with different thicknesses at varying skin-to-spoiler separation (SSS). In the same condition, the dose was measured with bolus and compared with beam spoiler. The spoiler increased the surface and build-up dose and shifted the depth of maximum dose toward the surface. With a 10 MV x-ray beam and a optimal beam spoiler when treating a patient, a similar build-up dose with a 6 MV photon beam could be achieved, while maintaining a certain amount of skin spring. But it was provided higher surface dose under SSS of less than 5 cm, the spoiler thickness of more than 1.8 cm or more, and larger field size than 20 x 20 cm{sup 2} provided higher surface dose like bolus and obliterated the spin-sparing effect. the effects of the beam spoiler on beam profile was reduced with increasing depths. The lucite spoiler allowed using of a 10 MV photon beam for the radiation treatment of head and neck caner by yielding secondary scattered electron on the surface. The dose at superficial depth was increased and the depth of maximum dose was moved to near the skin surface. Spoiling the 10 MV x-ray beam resulted in treatment plans that maintained dose homogeneity without the consequence of increased skin reaction or treat volume underdose

  2. Track detector based dosimetry for therapeutic carbon beams

    CERN Document Server

    Osinga, J -M; Brabcová, K Pachnerová; Akselrod, M S; Jäkel, O; Davídková, M; Greilich, S

    2013-01-01

    The ability of plastic and fluorescent nuclear track detectors (PNTDs and FNTDs) to measure fluence and the linear energy transfer (LET) of clinical carbon ion beams was investigated. We employed coincident measurements with both systems and registered the results at the level of single tracks. Irradiations were performed in the entrance channel of the monoenergetic carbon ion beam covering the therapeutically useful energy range from 80 to 425 MeV/u. About 99 % of all primary particle tracks detected by both detectors were successfully matched, while 1 % of the particles were only detected by the FNTDs because of their superior spatial resolution. We conclude that both PNTDs and FNTDs are suitable for clinical carbon beam dosimetry with a detection efficiency of at least 98.82 % and 99.83 % respectively, if irradiations are performed with low fluence in the entrance channel of the ion beam. Additionally, a relationship between the mean LET as determined with PNTDs and the mean fluorescence amplitude of the p...

  3. HIGHLIGHTS LHC First Beam - Accelerating Science : 10 September 2008

    CERN Multimedia

    CERN Audiovisual Service

    2008-01-01

    First beam in the LHC - accelerating science A historic moment in the CERN Control Centre: the beam was successfully steered around the accelerator. Channel 1 : International Channel 2 : English guide A historic moment in the CERN Control Centre: the beam was successfully steered around the accelerator. Geneva, 10 September 2008. The first beam in the Large Hadron Collider at CERN1 was successfully steered around the full 27 kilometres of the world’s most powerful particle accelerator at 10h28 this morning. This historic event marks a key moment in the transition from over two decades of preparation to a new era of scientific discovery. “It’s a fantastic moment,” said LHC project leader Lyn Evans, “we can now look forward to a new era of understanding about the origins and evolution of the universe.” Starting up a major new particle accelerator takes much more than flipping a switch. Thousands of individual elements have to work in harmony, timings have to be synchronized to under a billionth of a...

  4. Practical biological spread-out Bragg peak design of carbon beam

    OpenAIRE

    Kim, Chang Hyeuk; Lee, Hwa-Ryun; Chang, Seduk; Jang, Hong Suk; Kim, Jeong Hwan; Park, Dong Wook; Hwang, Won Taek; Yang, Tea-Keun

    2015-01-01

    The carbon beams show more advantages on the biological properties compared with proton beams in radiation therapy. The carbon beam shows high linear energy transfer (LET) to medium and it increases the relative biological effectiveness (RBE). To design spread-out Bragg peak (SOBP) of biological dose using carbon beam, a practical method was purposed by using the linear-quadratic (LQ) model and Geant4 based Monte Carlo simulation code. The various Bragg peak profiles and LET was calculated fo...

  5. Response of SOI image sensor to therapeutic carbon ion beam

    CERN Document Server

    Matsumura, Akihiko

    2015-01-01

    Carbon ion radiotherapy is known as a less invasive cancer treatment. The radiation quality is an important parameter to evaluate the biological effect and the clinical dose from the measured physical dose. The performance of SOPHIAS detector, which is the SOI image sensor having a wide dynamic range and large active area, was tested by using therapeutic carbon ion beam at Gunma University Heavy Ion Medical Center (GHMC). It was shown that the primary carbon and secondary particles can be distinguishable by SOPHIAS detector. On the other hand, a LET dependence was observed especially at the high LET region. This phenomenon will be studied by using the device simulator together with Monte Carlo simulation.

  6. 10 September: the LHC’s first circulating beam

    CERN Multimedia

    On 10 September, a first beam of protons will circulate in the LHC. The first moments in the life of the LHC will be an exciting time for the CERN staff, and will be captured by more than 250 media organizations from all over the world. The first injection of the beam into the machine will be between 9:00 and 10:00 a. m. At 9:15 the LHC project leader, Lyn Evans, will give a brief explanation of the day’s proceedings in French followed by some words from Robert Aymar, CERN Director general. CERN personnel are invited to follow the first beam day events, which will be shown in the following rooms around CERN: All day: Council Chamber, Main Auditorium, IT Auditorium, AB Auditorium Prévessin, Conference Room 40-S2-A01, Conference Room 40-S2-C01. Afternoon: AB Auditorium Meyrin, AT Auditorium. Please note that the event will also be webcast but, given the limited number of connections, this option is intended for use of the public outside CERN. CERN personnel are encouraged to follow the event from the confe...

  7. Carbon dust particles in a beam-plasma discharge

    Science.gov (United States)

    Koval, O. A.; Vizgalov, V.; Shalpegin, A. V.

    2016-09-01

    This paper focuses on dynamics of micro-sized carbon dust grains in beam-plasma discharge (BPD) plasmas. It was demonstrated that injected dust particles can be captured and transported along the discharge. Longitudinal average velocity of the particles in the central area of the plasma column was 17 m/sec, and 2 m/sec in the periphery. Dust injection caused a decrease of emission intensity of metastable nitrogen molecular ion. This effect is suggested for a spectroscopy method for particles’ potential measurements. Five-micron radius carbon dust grains obtained potential above 500 V in the experiments on PR-2 installation, proving the feasibility of BPDs for the charging of fine dust particles up to high potential values, unattainable in similar plasma conditions.

  8. Measurement and Simulation of Beam Centering on CYCIAE-10

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The beam centering is very important for the compact cyclotron, especially for the cyclotrons with the axial injection. It is critical that the cyclotron has a good beam centering to increase the beam current and reduce the beam loss. In the accelerating process,

  9. Carbon doping in molecular beam epitaxy of GaAs from a heated graphite filament

    Science.gov (United States)

    Malik, R. J.; Nottenberg, R. N.; Schubert, E. F.; Walker, J. F.; Ryan, R. W.

    1988-01-01

    Carbon doping of GaAs grown by molecular beam epitaxy has been obtained for the first time by use of a heated graphite filament. Controlled carbon acceptor concentrations over the range of 10 to the 17th-10 to the 20th/cu cm were achieved by resistively heating a graphite filament with a direct current power supply. Capacitance-voltage, p/n junction and secondary-ion mass spectrometry measurements indicate that there is negligible diffusion of carbon during growth and with postgrowth rapid thermal annealing. Carbon was used for p-type doping in the base of Npn AlGaAs/GaAs heterojunction bipolar transistors. Current gains greater than 100 and near-ideal emitter heterojunctions were obtained in transistors with a carbon base doping of 1 x 10 to the 19th/cu cm. These preliminary results indicate that carbon doping from a solid graphite source may be an attractive substitute for beryllium, which is known to have a relatively high diffusion coefficient in GaAs.

  10. Electron beam influence on the carbon contamination of electron irradiated hydroxyapatite thin films

    International Nuclear Information System (INIS)

    Highlights: • Carbon contamination mechanisms of electron-beam-irradiated hydroxyapatite. • Atomic force microscopy phase imaging used to detect carbon contamination. • Carbon contamination dependence on electron energy, irradiation time, beam current. • Simulation of backscattered electrons confirms the experimental results. - Abstract: Electron beam irradiation which is considered a reliable method for tailoring the surface charge of hydroxyapatite is hindered by carbon contamination. Separating the effects of the carbon contamination from those of irradiation-induced trapped charge is important for a wide range of biological applications. In this work we focus on the understanding of the electron-beam-induced carbon contamination with special emphasis on the influence of the electron irradiation parameters on this phenomenon. Phase imaging in atomic force microscopy is used to evaluate the influence of electron energy, beam current and irradiation time on the shape and size of the resulted contamination patterns. Different processes involved in the carbon contamination of hydroxyapatite are discussed

  11. Beam-dump/diagnostics box for a 10-kA 50-MeV, 50-ns electron beam

    International Nuclear Information System (INIS)

    We have developed a dump for the ATA beam that consists of a series of carbon plates whose collective thickness totals approximately 1.5 ranges at 50 MeV. The energy dissipated in the plates is radiated to a water-cooled wall. The dump is designed to dissipate up to 175 kW of average power. A small hole along the axis of the plates forms a beamlet that passes through an energy analyzer. The analyzer consists of a 600 bending magnet and two high-sensitivity beam-current/position monitors. The ratio of the beamlet current to full current is used to estimate the beam emittance

  12. Experiments with the newly available carbon beams at ISOLDE

    CERN Multimedia

    Garcia borge, M J; Koester, U H; Koldste, G T

    2002-01-01

    Recent target-ions-source developments at ISOLDE providing significantly increased yields for carbon isotopes, open up for new and intriguing experiments. We propose to exploit this in two different ways. In particular we wish to do an elastic resonance scattering experiment of $^{9}$C on a proton target to gain information on the particle unbound system $^{10}$N. Furthermore we wish to perform decay experiments of the neutron-rich carbon isotopes, with special focus on $^{17-19}$C but also including a test to see whether the even more neutron-rich isotopes $^{20,22}$C are accessible at ISOLDE.

  13. Enhancement of neutral beam deposition in hydrogen discharge using carbon pellet injection in LHD

    International Nuclear Information System (INIS)

    The central ion temperature in the large helical device (LHD), as measured by charge-exchange recombination spectroscopy, has been improved to a record 5.6 keV by combining 21 MW of neutral beam heating with the injection of a carbon pellet. The intensity of the neutral beam emission of the hydrogen Balmer line (Hα: n=3 → 2) was observed to weaken along the beam injection axis following the carbon pellet injection due to the increased beam attenuation. The beam-emission intensity was reconstructed by calculating the density distribution, and the beam-stopping coefficients, along a beam injection axis and was found to fit well to the measured beam-emission for a mixed hydrogen and carbon target plasma. The dynamics of the neutral beam deposition power and the carbon fraction were estimated from the beam-emission measurements using data from ADAS. We conclude that the beam deposition power in a carbon pellet discharge is enhanced over that of a pure hydrogen discharge. (author)

  14. Kinetics of ion beam deposition of carbon at room temperature

    International Nuclear Information System (INIS)

    Growth rates of carbon films grown by ion beam deposition using methane gas were measured in situ as a function of deposition conditions. The methane pressure dependence of the growth rate was used to measure the cross-section for charge exchange. Variations in deposition rate per incident energetic particle found for each ion energy were related to ion current density. It was found that rates of growth per incident energetic specie were (i) largest for the smallest current densities, (ii) decreased monotonically with increasing current density, and (iii) were consistently larger than can be explained by deposition directly from the energetic flux alone. These observations were interpreted in terms of irradiation-induced surface interactions which promote chemisorption of methane physisorbed from the ambient atmosphere. (orig.)

  15. In silico carbon molecular beam epitaxial growth of graphene on the h-BN substrate: carbon source effect on van der Waals epitaxy

    Science.gov (United States)

    Lee, Jonghoon; Varshney, Vikas; Park, Jeongho; Farmer, Barry L.; Roy, Ajit K.

    2016-05-01

    during the initial phase of graphene growth simulation using a carbon trimer beam is captured. An initially sp hybridized carbon atom (red colored) becomes sp2 hybridized as a result of additional covalent bonding with the impinging carbon trimer. As the bond angle around the red carbon changes from 180 degree (sp) to 120 degree (sp2), nearby carbon atoms enclose to form a hexagon structure composed of 6 carbon atoms. See DOI: 10.1039/c6nr01396a

  16. Biological intercomparison using gut crypt survivals for proton and carbon-ion beams

    International Nuclear Information System (INIS)

    Charged particle therapy depends on biological information for the dose prescription. Relative biological effectiveness or RBE for this requirement could basically be provided by experimental data. As RBE values of protons and carbon ions depend on several factors such as cell/tissue type, biological endpoint, dose and fractionation schedule, a single RBE value could not deal with all different radiosensitivities. However, any biological model with accurate reproducibility is useful for comparing biological effectiveness between different facilities. We used mouse gut crypt survivals as endpoint, and compared the cell killing efficiency of proton beams at three Japanese facilities. Three Linac X-ray machines with 4 and 6 MeV were used as reference beams, and there was only a small variation (coefficient of variance<2%) in biological effectiveness among them. The RBE values of protons relative to Linac X-rays ranged from 1.0 to 1.11 at the middle of a 6-cm SOBP (spread-out Bragg peak) and from 0.96 to 1.01 at the entrance plateau. The coefficient of variance for protons ranged between 4.0 and 5.1%. The biological comparison of carbon ions showed fairly good agreement in that the difference in biological effectiveness between National Institute of Radiological Sciences (NIRS)/ Heavy Ion Medical Accelerator in Chiba (HIMAC) and Gesellschaft fur Schwerionenforschung (GSI)/Heavy Ion Synchrotron (SIS) was 1% for three positions within the 6-cm SOBP. The coefficient of variance was <1.7, <0.6 and <1.6% for proximal, middle and distal SOBP, respectively. We conclude that the inter-institutional variation of biological effectiveness is smaller for carbon ions than protons, and that beam-spreading methods of carbon ions do not critically influence gut crypt survival. (author)

  17. Carbon-ion beam irradiation kills X-ray-resistant p53-null cancer cells by inducing mitotic catastrophe.

    Directory of Open Access Journals (Sweden)

    Napapat Amornwichet

    Full Text Available BACKGROUND AND PURPOSE: To understand the mechanisms involved in the strong killing effect of carbon-ion beam irradiation on cancer cells with TP53 tumor suppressor gene deficiencies. MATERIALS AND METHODS: DNA damage responses after carbon-ion beam or X-ray irradiation in isogenic HCT116 colorectal cancer cell lines with and without TP53 (p53+/+ and p53-/-, respectively were analyzed as follows: cell survival by clonogenic assay, cell death modes by morphologic observation of DAPI-stained nuclei, DNA double-strand breaks (DSBs by immunostaining of phosphorylated H2AX (γH2AX, and cell cycle by flow cytometry and immunostaining of Ser10-phosphorylated histone H3. RESULTS: The p53-/- cells were more resistant than the p53+/+ cells to X-ray irradiation, while the sensitivities of the p53+/+ and p53-/- cells to carbon-ion beam irradiation were comparable. X-ray and carbon-ion beam irradiations predominantly induced apoptosis of the p53+/+ cells but not the p53-/- cells. In the p53-/- cells, carbon-ion beam irradiation, but not X-ray irradiation, markedly induced mitotic catastrophe that was associated with premature mitotic entry with harboring long-retained DSBs at 24 h post-irradiation. CONCLUSIONS: Efficient induction of mitotic catastrophe in apoptosis-resistant p53-deficient cells implies a strong cancer cell-killing effect of carbon-ion beam irradiation that is independent of the p53 status, suggesting its biological advantage over X-ray treatment.

  18. Measurement of inclusive charged current interactions on carbon in a few-GeV neutrino beam

    CERN Document Server

    jima, Y Naka; Brice, S J; Bugel, L; Catala-Perez, J; Cheng, G; Conrad, J M; Djurcic, Z; Dore, U; Finley, D A; Franke, A J; Giganti, C; Gomez-Cadenas, J J; Guzowski, P; Hanson, A; Hayato, Y; Hiraide, K; Jover-Manas, G; Karagiorgi, G; Katori, T; Kobayashi, Y K; Kobilarcik, T; Kubo, H; Kurimoto, Y; Louis, W C; Loverre, P F; Ludovici, L; Mahn, K B M; Mariani, C; Masuike, S; Matsuoka, K; McGary, V T; Metcalf, W; Mills, G B; Mitsuka, G; Miyachi, Y; Mizugashira, S; Moore, C D; Nakaya, T; Napora, R; Nienaber, P; Orme, D; Otani, M; Russell, A D; Sanchez, F; Shaevitz, M H; Shibata, T -A; Sorel, M; Stefanski, R J; Takei, H; Tanaka, H -K; Tanaka, M; Tayloe, R; Taylor, I J; Tesarek, R J; Uchida, Y; Van de Water, R; Walding, J J; Wascko, M O; White, H B; Yokoyama, M; Zeller, G P; Zimmerman, E D

    2010-01-01

    The SciBooNE Collaboration reports a measurement of inclusive charged current interactions of muon neutrinos on carbon with an average energy of 0.8~GeV using the Fermilab Booster Neutrino Beam. We compare our measurement with two neutrino interaction simulations: NEUT and NUANCE. The charged current interaction rates (product of flux and cross section) are extracted by fitting the muon kinematics, with a precision of 6-15% for the energy dependent and 3% for the energy integrated analyses. We also extract CC inclusive interaction cross sections from the observed rates, with a precision of 10-30% for the energy dependent and 8% for the energy integrated analyses. This is the first measurement of the CC inclusive cross section on carbon around 1 GeV. These results can be used to convert previous SciBooNE cross section ratio measurements to absolute cross section values.

  19. Radiation biophysical studies with mammalian cells and a modulated carbon ion beam

    International Nuclear Information System (INIS)

    Chinese hamster (V-79) and human kidney (T-1) cells were irradiated in stirred suspensions placed at various positions in the plateau and extended Bragg peak of a 400-MeV/amu carbon ion beam. The range of the ions was modulated by a lead (translational) ridge filter and a brass (spiral) ridge filter designed to produce extended peaks of approximately 4 and 10 cm, respectively. Stationary-phase and G1-phase populations of Chinese hamster cells were found to have different absolute radiosensitivities which, in turn, were different from that of asynchronous human kidney cells. The increase in relative biological effectiveness (RBE) observed as carbon ions were slowed down and stopped in water was similar for the three cell populations at doses greater than 400 rad. At lower doses the RBE was greater for the hamster cell populations than for the human kidney cells. The gain in RBE (at the 50% survival level) between the plateaus and the middle region of the extended peaks was approximately 2.0 and 1.7 for the 4- and 10-cm extended peaks, respectively. Oxygen enhancement ratios (OER) were determined at the 10% survival levels with stationary-phase populations of hamster cells. Values of 2.8, 2.65, and 1.65 were obtained for the OER of 220-kV x rays, plateau carbon, and the middle region of the 4-cm carbon peak, respectively. Across the 10-cm carbon peak the OER was found to vary between values of 2.4 to 1.55 from the proximal to distal positions

  20. Interaction of the CERN Large Hadron Collider (LHC) Beam with Carbon Collimators

    CERN Document Server

    Schmidt, R; Hoffmann, Dieter H H; Kadi, Y; Shutov, A; Piriz, AR

    2006-01-01

    The LHC will operate at an energy of 7 TeV with a luminosity of 1034cm-2s-1. This requires two beams, each with 2808 bunches. The energy stored in each beam of 362 MJ. In a previous paper the mechanisms causing equipment damage in case of a failure of the machine protection system was discussed, assuming that the entire beam is deflected into a copper target [1, 2]. Another failure scenario is the deflection of beam into carbon material. Carbon collimators and beam absorbers are installed in many locations around the LHC to diffuse or absorb beam losses. Since the collimator jaws are close to the beam, it is very likely that they are hit first when the beam is accidentally deflected. Here we present the results of two-dimensional hydrodynamic simulations of the heating of a solid carbon cylinder irradiated by the LHC beam with nominal parameters, carried out using the BIG-2 computer code [3] while the energy loss of the 7 TeV protons in carbon is calculated using the well known FLUKA code [4]. Our calculation...

  1. Imaging the interphase of carbon fiber composites using transmission electron microscopy:Preparations by focused ion beam, ion beam etching, and ultramicrotomy

    Institute of Scientific and Technical Information of China (English)

    Wu Qing; Li Min; Gu Yizhuo; Wang Shaokai; Zhang Zuoguang

    2015-01-01

    Three sample preparation techniques, focused ion beam (FIB), ion beam (IB) etching, and ultramicrotomy (UM) were used in comparison to analyze the interphase of carbon fiber/epoxy composites using transmission electron microscopy. An intact interphase with a relatively uniform thickness was obtained by FIB, and detailed chemical analysis of the interphase was investigated by electron energy loss spectroscopy. It shows that the interphase region is 200 nm wide with an increasing oxygen-to-carbon ratio from 10% to 19% and an almost constant nitrogen-to-carbon ratio of about 3%. However, gallium implantation of FIB tends to hinder fine structure analysis of the interphase. For IB etching, the interphase region is observed with transition morphology from amorphous resin to nano-crystalline carbon fiber, but the uneven sample thickness brings difficulty for quantitative chemical analysis. Moreover, UM tends to cause damage and/or deformation on the interphase. These results are meaningful for in-depth understanding on the interphase characteristic of carbon fiber composites.

  2. Dosimetric characterization and application of an imaging beam line with a carbon electron target for megavoltage cone beam computed tomography.

    Science.gov (United States)

    Flynn, Ryan T; Hartmann, Julia; Bani-Hashemi, Ali; Nixon, Earl; Alfredo, R; Siochi, C; Pennington, Edward C; Bayouth, John E

    2009-06-01

    Imaging dose from megavoltage cone beam computed tomography (MVCBCT) can be significantly reduced without loss of image quality by using an imaging beam line (IBL), with no flattening filter and a carbon, rather than tungsten, electron target. The IBL produces a greater keV-range x-ray fluence than the treatment beam line (TBL), which results in a more optimal detector response. The IBL imaging dose is not necessarily negligible, however. In this work an IBL was dosimetrically modeled with the Philips Pinnacle3 treatment planning system (TPS), verified experimentally, and applied to clinical cases. The IBL acquisition dose for a 200 degrees gantry rotation was verified in a customized acrylic cylindrical phantom at multiple imaging field sizes with 196 ion chamber measurements. Agreement between the measured and calculated IBL dose was quantified with the 3D gamma index. Representative IBL and TBL imaging dose distributions were calculated for head and neck and prostate patients and included in treatment plans using the imaging dose incorporation (IDI) method. Surface dose was measured for the TBL and IBL for four head and neck cancer patients with MOSFETs. The IBL model, when compared to the percentage depth dose and profile measurements, had 97% passing gamma indices for dosimetric and distance acceptance criteria of 3%, 3 mm, and 100% passed for 5.2%, 5.2 mm. For the ion chamber measurements of phantom image acquisition dose, the IBL model had 93% passing gamma indices for acceptance criteria of 3%, 3 mm, and 100% passed for 4%, 4 mm. Differences between the IBL- and TBL-based IMRT treatment plans created with the IDI method were dosimetrically insignificant for both the prostate and head and neck cases. For IBL and TBL beams with monitor unit values that would result in the delivery of the same dose to the depth of maximum dose under standard calibration conditions, the IBL imaging surface dose was higher than the TBL imaging surface dose by an average of 18

  3. Ion beam deposition of amorphous carbon films with diamond like properties

    Science.gov (United States)

    Angus, John C.; Mirtich, Michael J.; Wintucky, Edwin G.

    1982-01-01

    Carbon films were deposited on silicon, quartz, and potassium bromide substrates from an ion beam. Growth rates were approximately 0.3 micron/hour. The films were featureless and amorphous and contained only carbon and hydrogen in significant amounts. The density and carbon/hydrogen ratio indicate the film is a hydrogen deficient polymer. One possible structure, consistent with the data, is a random network of methylene linkages and tetrahedrally coordinated carbon atoms.

  4. Production of a sub-10 fs electron beam with 107 electrons

    Science.gov (United States)

    Han, Jang-Hui

    2011-05-01

    We study the possibility to produce a 1.6 pC electron beam (107 electrons) with a bunch length of less than 10 fs and a beam energy of a few MeV. Such a short, relativistic beam will be useful for an electron diffraction experiment with a 10 fs time resolution. An electron beam with 107 electrons will allow a single-shot experiment with a laser pulse pump and an electron beam probe. In this design, an S-band photocathode gun is used for generating and accelerating a beam and a buncher consisting of two S-band four-cell cavities is used for temporally compressing the beam. Focusing solenoids control the beam transverse divergence and size at the sample. Numerical optimization is carried out to achieve a beam with a 4 fs full-width-at-half-maximum length, a 26 microradian root-mean-square divergence, and a 2 nm transverse coherence length at a 3.24 MeV beam energy. When state-of-the-art rf stability is considered, beam arrival time jitter at the sample is calculated to be about 10 fs.

  5. Sub-10 nm focused electron beam induced deposition

    NARCIS (Netherlands)

    Van Dorp, W.F.

    2008-01-01

    Work started with a critical review of literature from the past 70-odd years. The review shows that the physical processes occurring in EBID are generally well understood. By combining models for electron scattering in a solid and electron beam induced heating and knowledge of growth regimes, the ma

  6. Electron Cloud in Steel Beam Pipe vs Titanium Nitride Coated and Amorphous Carbon Coated Beam Pipes in Fermilab's Main Injector

    Energy Technology Data Exchange (ETDEWEB)

    Backfish, Michael

    2013-04-01

    This paper documents the use of four retarding field analyzers (RFAs) to measure electron cloud signals created in Fermilab’s Main Injector during 120 GeV operations. The first data set was taken from September 11, 2009 to July 4, 2010. This data set is used to compare two different types of beam pipe that were installed in the accelerator. Two RFAs were installed in a normal steel beam pipe like the rest of the Main Injector while another two were installed in a one meter section of beam pipe that was coated on the inside with titanium nitride (TiN). A second data run started on August 23, 2010 and ended on January 10, 2011 when Main Injector beam intensities were reduced thus eliminating the electron cloud. This second run uses the same RFA setup but the TiN coated beam pipe was replaced by a one meter section coated with amorphous carbon (aC). This section of beam pipe was provided by CERN in an effort to better understand how an aC coating will perform over time in an accelerator. The research consists of three basic parts: (a) continuously monitoring the conditioning of the three different types of beam pipe over both time and absorbed electrons (b) measurement of the characteristics of the surrounding magnetic fields in the Main Injector in order to better relate actual data observed in the Main Injector with that of simulations (c) measurement of the energy spectrum of the electron cloud signals using retarding field analyzers in all three types of beam pipe.

  7. Emulsion Cloud Chamber technique to measure the fragmentation of a high-energy carbon beam

    OpenAIRE

    De Lellis, G.; Buontempo., S; Di Capua, F.; Marotta, A; Migliozzi, P.; Petukhov, Y.; Pistillo, C; Russo, A; Lavina, L. Scotto; Strolin, P.(Dipartimento di Fisica dell’Università Federico II di Napoli, 80125 , Naples, Italy); Tioukov, V.; Ariga, A.(Albert Einstein Center for Fundamental Physics, Laboratory for High Energy Physics (LHEP), University of Bern, CH-3012, Bern, Switzerland); Naganawa, N.; Toshito, T.; Furusawa, Y.

    2007-01-01

    Beams of Carbon nuclei are used or planned to be used in various centers for cancer treatment around the world because of their therapeutic advantages over proton beams. The knowledge of the fragmentation of Carbon nuclei when they interact with the human body is important to evaluate the spatial profile of their energy deposition in the tissues, hence the damage to the tissues neighboring the tumor. In this respect, the identification of the fragmentation products is a key element. We presen...

  8. Beam commissioning of a superconducting rotating-gantry for carbon-ion radiotherapy

    Science.gov (United States)

    Iwata, Y.; Fujimoto, T.; Matsuba, S.; Fujita, T.; Sato, S.; Furukawa, T.; Hara, Y.; Mizushima, K.; Saraya, Y.; Tansho, R.; Saotome, N.; Shirai, T.; Noda, K.

    2016-10-01

    A superconducting rotating-gantry for carbon-ion radiotherapy was developed. This isocentric gantry can transport carbon ions having kinetic energies of between E=430 and 48 MeV/u to an isocenter over an angle of ±180°, and is further capable of performing three-dimensional raster-scanning irradiation. Construction of the entire rotating-gantry system was completed by the end of September 2015. Prior to beam commissioning, phase-space distributions of extracted carbon beams from the synchrotron were deduced by using an empirical method. In this method, phase-space distributions at the extraction channel of the synchrotron were modeled with 8 parameters, and the best parameters were determined so as to minimize a difference between the calculated and measured beam profiles by using a simplex method. Based on the phase-space distributions, beam optics through the beam-transport lines as well as the rotating gantry were designed. Since horizontal and vertical beam emittances, as extracted slowly from the synchrotron, generally differ with each other, a horizontal-vertical beam coupling would occur when the gantry rotates. Thus, the size and shape of beam spots at the isocenter should vary depending on the gantry angle. To compensate for the difference in the emittances, we employed a method to utilize multiple Coulomb scattering of the beam particles by a thin scatterer. Having compensated for the emittances and designed beam optics through the rotating gantry, beam commissioning over various combinations of gantry angles and beam energies was performed. By finely tuning the superconducting quadrupoles of the rotating gantry, we could successfully obtain the designed beam quality, which satisfies the requirements of scanning irradiation.

  9. Shear strengthening of pre-damaged reinforced concrete beams with carbon fiber reinforced polymer sheet strips

    Institute of Scientific and Technical Information of China (English)

    Feras ALZOUBI; ZHANG Qi; LI Zheng-liang

    2007-01-01

    This paper presents the results of an experimental investigation on the response of pre-damaged reinforced concrete (RC) beam strengthened in shear using applied-epoxy unidirectional carbon fiber reinforced polymer (CFRP) sheet. The reasearch included four test rectangular simply supported RC beams in shear capacity. One is the control beam, two RC beams are damaged to a predetermined degree from ultimate shear capacity of the control beam, and the last beam is left without pre-damaged and then strengthened with using externally bonded carbon fiber reinforced polymer to upgrade their shear capacity. We focused on the damage degree to beams during strengthening, therefore, only the beams with side-bonded CFRPs strips and horizontal anchored strips were used. The results show the feasibility of using CFRPs to restore or increase the load-carrying capacity in the shear of damaged RC beams. The failure mode of all the CFRP-strengthened beams is debonding of CFRP vertical strips. Two prediction available models in ACI-440 and fib European code were compared with the experimental results.

  10. Bending of metal-filled carbon nanotube under electron beam irradiation

    Directory of Open Access Journals (Sweden)

    Abha Misra

    2012-03-01

    Full Text Available Electron beam irradiation induced, bending of Iron filled, multiwalled carbon nanotubes is reported. Bending of both the carbon nanotube and the Iron contained within the core was achieved using two approaches with the aid of a high resolution electron microscope (HRTEM. In the first approach, bending of the nanotube structure results in response to the irradiation of a pristine kink defect site, while in the second approach, disordered sites induce bending by focusing the electron beam on the graphite walls. The HRTEM based in situ observations demonstrate the potential for using electron beam irradiation to investigate and manipulate the physical properties of confined nanoscale structures.

  11. Numerical Investigation Of The Bombardment Of A Graphene Sheet By A Beam Of Carbon Atoms

    Directory of Open Access Journals (Sweden)

    O.V. Khomenko

    2009-01-01

    Full Text Available Classical molecular dynamics simulations of the bombardment of a graphene sheet by a beam of carbon atoms are carried out. Covalent bonds in the irradiated sample are described by the Brenner potential. The approximation of elastic balls interacting with graphene via the Lennard-Jones potential is used for particles in a beam. The influence of the energy and density of irradiating carbon atoms and of the presence of a thermostat on physical processes occurring during the collisions with the sample is investigated. Energy values of the particles in a beam, which are enough for the sample destruction, are defined.

  12. Enhancement of Charpy impact value by electron beam irradiation of carbon fiber reinforced polymer

    International Nuclear Information System (INIS)

    Influences of electron beam irradiation on Charpy impact value of carbon fiber reinforced polymer (CFRP) have been investigated. The irradiation, which is one of short-time treatments, enhanced the Charpy impact value of CFRP. Furthermore, strengthening of carbon fiber, ductility enhancement of polymer and interface effects on impact test explains the impact value enhancement of CFRP. (author)

  13. Using Pyrolysis Molecular Beam Mass Spectrometry to Characterize Soil Organic Carbon in Native Prairie Soils

    Science.gov (United States)

    The objective of this study was to characterize soil organic carbon (SOC) with pyrolysis molecular beam mass spectrometry (py-MBMS) and then to determine correlations between the mass spectra and associated soil characterization data. Both soil carbon chemistry and the organic forms in which SOC is...

  14. Enhanced electromagnetic properties of nickel nanoparticiles dispersed carbon fiber via electron beam irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yeong Ju; Kim, Hyun Bin; Lee, Seung Jun; Kang, Phil Hyun [Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of)

    2015-02-15

    Carbon fiber has received much attention owing to its properties, including a large surface-to-volume ratio, chemical and thermal stability, high thermal and electrical conductivity, and high mechanical strengths. In particular, magnetic nanopowder dispersed carbon fiber has been attractive in technological applications such as the electrochemical capacitor and electromagnetic wave shielding. In this study, the nickel-oxide-nanoparticle dispersed polyacrylonitrile (PAN) fibers were prepared through an electrospinning method. Electron beam irradiation was carried out with a 2.5 MeV beam energy to stabilize the materials. The samples were then heat treated for stabilization and carbonization. The nanofiber surface was analyzed using a field emission scanning electron microscope (FE-SEM). The crystal structures of the carbon matrix and nickel nanopowders were analysed using X-ray diffraction (XRD). In addition, the magnetic and electrical properties were analyzed using a vibrating sample magnetometer (VSM) and 4 point probe. As the irradiation dose increases, the density of the carbon fiber was increased. In addition, the electrical properties of the carbon fiber improved through electron beam irradiation. This is because the amorphous region of the carbon fiber decreases. This electron beam effect of PAN fibers containing nickel nanoparticles confirmed their potential as a high performance carbon material for various applications.

  15. Treatment of industrial effluents using electron beam accelerator and adsorption with activated carbon: a comparative study

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira Sampa, M.H. de E-mail: mhosampa@ipen.br; Rela, Paulo Roberto; Las Casas, Alexandre; Nunes Mori, Manoel; Lopes Duarte, Celina

    2004-10-01

    This paper presents preliminary results of a study that compares the use of electron beam processing and activated carbon adsorption to clean up a standardized organic aqueous solution and a real industrial effluent. The electron beam treatment was performed in a batch system using the IPEN's Electron Beam Accelerators from Radiation Dynamics Inc., Dynamitron 37.5 kW. The granular activated carbon removal treatment was performed using charcoal made from wood 'pinus'. If the adequate irradiation dose is delivered to the organic pollutant, it is possible to conclude for the studied compounds that the Electron Beam Process is similar to the activated carbon process in organic removal efficiency.

  16. Practical biological spread-out Bragg peak design of carbon beam

    CERN Document Server

    Kim, Chang Hyeuk; Chang, Seduk; Jang, Hong Suk; Kim, Jeong Hwan; Park, Dong Wook; Hwang, Won Taek; Yang, Tea-Keun

    2015-01-01

    The carbon beams show more advantages on the biological properties compared with proton beams in radiation therapy. The carbon beam shows high linear energy transfer (LET) to medium and it increases the relative biological effectiveness (RBE). To design spread-out Bragg peak (SOBP) of biological dose using carbon beam, a practical method was purposed by using the linear-quadratic (LQ) model and Geant4 based Monte Carlo simulation code. The various Bragg peak profiles and LET was calculated for each slice at the target region. To generate appropriate biological SOBP, a set of weighting factor, which is a power function in terms of energy step, was applied to the obtained each physical dose. The designed biological SOBP showed 1.34 % of uniformity.

  17. Three dimensional reconstruction of therapeutic carbon ion beams in phantoms using single secondary ion tracks

    CERN Document Server

    Reinhart, Anna Merle; Jakubek, Jan; Martisikova, Maria

    2016-01-01

    Carbon ion beam radiotherapy enables a very localised dose deposition. However, already small changes in the patient geometry or positioning errors can significantly distort the dose distribution. A live monitoring system of the beam delivery within the patient is therefore highly desirable and could improve patient treatment. We present a novel three-dimensional imaging method of the beam in the irradiated object, exploiting the measured tracks of single secondary ions emerging under irradiation. The secondary particle tracks are detected with a TimePix stack, a set of parallel pixelated semiconductor detectors. We developed a three-dimensional reconstruction algorithm based on maximum likelihood expectation maximisation. We demonstrate the applicability of the new method in an irradiation of a cylindrical PMMA phantom of human head size with a carbon ion pencil beam of 226MeV/u. The beam image in the phantom is reconstructed from a set of 9 discrete detector positions between -80 and 50 degrees from the bea...

  18. Different effects of carbon ion beams and X-rays on clonogenic survival and DNA repair in human pancreatic cancer stem-like cells

    International Nuclear Information System (INIS)

    Purpose: The effects of a carbon ion beam and X-rays on human pancreatic cancer stem-like cells were examined from the point of view of clonogenic survival and DNA repair. Materials and methods: Human pancreatic cancer stem-like cells were treated with and without carbon ion and X-ray irradiation, and then colony, spheroid and tumor formation assays as well as γH2AX foci formation assay were performed. Results: The relative biological effectiveness (RBE) values of a carbon ion beam relative to X-ray for the MIA PaCa-2 and BxPc-3 cells at the D10 values were 1.85–2.10. The ability for colony, spheroid formation, and tumorigenicity from cancer stem-like CD44+/CD24+ cells is significantly higher than that from non-cancer stem-like CD44−/CD24−cells. FACS data showed that CD44+/CD24+ cells were more highly enriched after X-rays compared to carbon ion irradiation at isoeffective doses. The RBE values for the carbon ion beam relative to X-ray at the D10 levels for CD44+/CD24+ cells were 2.0–2.19. The number of γH2AX foci in CD44−/CD24− cells was higher than that of CD44+/CD24+ cells after irradiation with either X-ray or carbon ion beam. The number of γH2AX foci in CD44+/CD24+ cells was almost the same in the early time, but it persists significantly longer in carbon ion beam irradiated cells compared to X-rays. Conclusions: Carbon ion beam has superior potential to kill pancreatic cancer stem cell-like cells, and prolonged induction of DNA damage might be one of the pivotal mechanisms of its high radiobiological effects compared to X-rays.

  19. Effect of electron beam irradiation on the properties of carbon fiber

    International Nuclear Information System (INIS)

    Carbon fibers are used as a reinforcement material in an epoxy matrix in advanced composites due to their high mechanical strength, rigidity and low specific density. An important aspect of the mechanical properties of composites is associated to the adhesion between the surface of the carbon fiber and the epoxy matrix. This paper aimed to evaluate the effects of electron beam irradiation on the physicochemical properties of carbon fibers to obtain better adhesion properties in resultant composite. Chemical structure and surface of carbon fiber were determined by FT-IR, elemental analysis and X-ray photoelectron spectroscopy, which indicated that the oxygen content increased significantly with increasing the radiation dose. Thermal stability of the carbon fibers was studied via the thermal gravimetric analysis. Surface morphology of carbon fiber was analyzed by scanning electron microscope. It was found that the degree of surface roughness was increased by electron beam irradiation

  20. Stress corrosion cracking tests on electron beam welded carbon steel specimens in carbonate-bicarbonate solution

    International Nuclear Information System (INIS)

    Stress corrosion cracking tests have been performed on tapered carbon steel test pieces containing electron beam welds with a view to defining susceptibility to such cracking in a carbonate-bicarbonate solution at 90 C and an appropriate electrode potential. The tests involved applying cyclic loads to the specimens and it is shown that the threshold stress for cracking reduces linearly with increase in the magnitude of the cyclic load component. Extrapolation of these trends to zero fluctuating stress indicates static load threshold stresses in the vicinity of the yield stress (i.e. about 300 N/mm2 for parent plate without a weld, 400 N/mm2 for specimens with welds on one side only and 600 N/mm2 for specimens having welds penetrating through the thickness of the specimen). The averages of the maximum crack velocities observed were least for parent plate material and greatest for weld metal, the former being essentially intergranular in morphology and the latter mostly transgranular, with heat affected zone material being intermediate between these extremes. (author)

  1. Strain measurements on concrete beam and carbon fiber cable with distributed optical fiber Bragg grating sensors

    Science.gov (United States)

    Nellen, Philipp M.; Bronnimann, Rolf; Sennhauser, Urs J.; Askins, Charles G.; Putnam, Martin A.

    1996-09-01

    We report on civil engineering applications of wavelength multiplexed optical fiber Bragg grating arrays directly produced on the draw tower for testing and surveying advanced structures and materials such as carbon fiber reinforced concrete elements and prestressing cables. We equipped a 6 by 0.9 by 0.5 m concrete beam, which was reinforced with carbon fiber reinforced epoxy laminates, and a 7-m long prestressing carbon fiber cable made of seven twisted strands, with optical fiber Bragg grating sensors. Static strains up to 8000 micrometers/m and dynamic strains up to 1200 micrometers/m were measured with a Michelson interferometer used as Fourier spectrometer with a resolution of about 10 micrometers/m for all sensors. Comparative measurements with electrical resistance strain gauges were in good agreement with the fiber optical results. We installed the fiber sensors in two different arrangements: some Bragg grating array elements measured local strain while others were applied in an extensometric configuration to measure moderate strain over a base length of 0.1 to 1 m.

  2. Water equivalent thickness values of materials used in beams of protons, helium, carbon and iron ions.

    Science.gov (United States)

    Zhang, Rui; Taddei, Phillip J; Fitzek, Markus M; Newhauser, Wayne D

    2010-05-01

    Heavy charged particle beam radiotherapy for cancer is of increasing interest because it delivers a highly conformal radiation dose to the target volume. Accurate knowledge of the range of a heavy charged particle beam after it penetrates a patient's body or other materials in the beam line is very important and is usually stated in terms of the water equivalent thickness (WET). However, methods of calculating WET for heavy charged particle beams are lacking. Our objective was to test several simple analytical formulas previously developed for proton beams for their ability to calculate WET values for materials exposed to beams of protons, helium, carbon and iron ions. Experimentally measured heavy charged particle beam ranges and WET values from an iterative numerical method were compared with the WET values calculated by the analytical formulas. In most cases, the deviations were within 1 mm. We conclude that the analytical formulas originally developed for proton beams can also be used to calculate WET values for helium, carbon and iron ion beams with good accuracy.

  3. Water equivalent thickness values of materials used in beams of protons, helium, carbon and iron ions.

    Science.gov (United States)

    Zhang, Rui; Taddei, Phillip J; Fitzek, Markus M; Newhauser, Wayne D

    2010-05-01

    Heavy charged particle beam radiotherapy for cancer is of increasing interest because it delivers a highly conformal radiation dose to the target volume. Accurate knowledge of the range of a heavy charged particle beam after it penetrates a patient's body or other materials in the beam line is very important and is usually stated in terms of the water equivalent thickness (WET). However, methods of calculating WET for heavy charged particle beams are lacking. Our objective was to test several simple analytical formulas previously developed for proton beams for their ability to calculate WET values for materials exposed to beams of protons, helium, carbon and iron ions. Experimentally measured heavy charged particle beam ranges and WET values from an iterative numerical method were compared with the WET values calculated by the analytical formulas. In most cases, the deviations were within 1 mm. We conclude that the analytical formulas originally developed for proton beams can also be used to calculate WET values for helium, carbon and iron ion beams with good accuracy. PMID:20371908

  4. Irradiation of 135 MeV/u carbon and neon beams for studies of radiation biology

    International Nuclear Information System (INIS)

    A heavy ion irradiation system was designed and constructed at RIKEN ring cyclotron facility for studies of radiation physics and radiation biology. Carbon and neon beams of 135 MeV/u were firstly used for the experiments. A pair of wobbler magnets and a scatterer were used for obtaining the uniform radiation field of about 10 cm in diameter. A parallel plate ionization chamber was used for dose monitoring. A range shifter was used for degrading the initial energy of the heavy ions. Precise depth dose distributions were measured by a small parallel plate ionization chamber and a variable length water column. LET (linear energy transfer) of the heavy ion radiation fields were measured by a parallel plate proportional chamber. From these basic measurements, biological experiments using these heavy ions are now carried out at this facility. (author)

  5. Cell survival in carbon beams - comparison of amorphous track model predictions

    DEFF Research Database (Denmark)

    Grzanka, L.; Greilich, S.; Korcyl, M.;

    Introduction: Predictions of the radiobiological effectiveness (RBE) play an essential role in treatment planning with heavy charged particles. Amorphous track models ( [1] , [2] , also referred to as track structure models) provide currently the most suitable description of cell survival under ion...... distribution models, and gamma response models was developed. This software can be used for direct numerical comparison between the models, submodels and their parameters and experimental data. In the present paper, we look at 10%-survival data from cell lines irradiated in vitro with carbon and proton beams...... irradiation. The aim of this paper is to compare the predictions from different amorphous approaches found in the literature - more specifically the phenomenological, analytical model by Katz and co-workers [1] and a Monte-Carlo based full as implemented for example in the local effect model by Scholz et al...

  6. Nano-carbon black and carbon fiber as conductive materials for the diagnosing of the damage of concrete beam

    OpenAIRE

    Yining Ding; Zhipei Chen; Zhibo Han; Yulin Zhang; Torgal, Fernando Pacheco

    2013-01-01

    The nano-carbon black (NCB) and carbon fiber (CF) as electric conductive materials were added into the concrete. The effect of the NCB and CF on the mechanical properties and on the fractional change in resistance (FCR) of concrete was investigated. The relationships among the FCR, the strain of initial geometrical neutral axis (IGNA) and the beam damage degree were developed. The results showed that the relationship between the FCR and IGNA strain can be described by the First Or...

  7. Geant4 Simulation Study of Dose Distribution and Energy Straggling for Proton and Carbon Ion Beams in Water

    OpenAIRE

    Zhao Qiang; Zhang Zheng; Li Yang

    2016-01-01

    Dose distribution and energy straggling for proton and carbon ion beams in water are investigated by using a hadrontherapy model based on the Geant4 toolkit. By gridding water phantom in N×N×N voxels along X, Y and Z axes, irradiation dose distribution in all the voxels is calculated. Results indicate that carbon ion beams have more advantages than proton beams. Proton beams have bigger width of the Bragg peak and broader lateral dose distribution than carbon ion beams for the same position o...

  8. Particle beam radiation therapy using carbon ions and protons for oligometastatic lung tumors

    International Nuclear Information System (INIS)

    A study was undertaken to analyze the efficacy and feasibility of particle beam radiation therapy (PBRT) using carbon ions and protons for the treatment of patients with oligometastatic lung tumors. A total of 47 patients with 59 lesions who underwent PBRT for oligometastatic lung tumors between 2003 and 2011 were included in this study. Patient median age was 66 (range, 39–84) years. The primary tumor site was the colorectum in 11 patients (23.4%), lung in 10 patients (21.3%) and a variety of other sites in 26 patients (55.3%). Thirty-one patients (66%) received chemotherapy prior to PBRT. Thirty-three lesions were treated with 320-MeV carbon ions and 26 were treated with 150- or 210-Mev protons in 1–4 portals. A median total dose of 60 (range, 52.8–70.2) GyE was delivered at the isocenter in 8 (range, 4–26) fractions. The median follow-up time was 17 months. The local control, overall survival and progression-free survival rates at 2 years were 79%, 54 and 27% respectively. PBRT-related toxicities were observed; six patients (13%) had grade 2 toxicity (including grade 2 radiation pneumonitis in 2) and six patients (13%) had grade 3 toxicity. Univariate analysis indicated that patients treated with a biologically equivalent dose of 10 (BED10) <110 GyE10, had a significantly higher local recurrence rate. Local control rates were relatively lower in the subsets of patients with the colorectum as the primary tumor site. No local progression was observed in metastases from colorectal cancer irradiated with a BED10 ≥ 110 GyE10. There was no difference in treatment results between proton and carbon ion therapy. PRBT is well tolerated and effective in the treatment of oligometastatic lung tumors. To further improve local control, high-dose PBRT with a BED10 ≥ 110 GyE10 may be promising. Further investigation of PBRT for lung oligometastases is warranted

  9. Hadron Cancer Therapy - relative merits of X-ray, proton and carbon beams

    Science.gov (United States)

    Jakel, Oliver

    2014-03-01

    -Heidelberg University has a long experience in radiotherapy with carbon ions, starting with a pilot project at GSI in 1997. This project was jointly run by the Dep. for Radiation Oncology of Heidelberg University, GSI and the German Cancer Research Center (DKFZ). A hospital based heavy ion center at Heidelberg University, the Heidelberg Ion Beam Therapy Center (HIT) was proposed by the same group in 1998 and started clinical operation in late 2009. Since then nearly 2000 patients were treated with beams of carbon ions and protons. Just recently the operation of the world's first and only gantry for heavy ions also started at HIT. Patient treatments are performed in three rooms. Besides that, a lot of research projects are run in the field of Medical Physics and Radiobiology using a dedicated experimental area and the possibility to use beams of protons, carbon, helium and oxygen ions being delivered with the raster scanning technique.

  10. Annual carbon balance of a peatland 10 yr following restoration

    Directory of Open Access Journals (Sweden)

    M. Strack

    2013-05-01

    Full Text Available Undisturbed peatlands represent long-term net sinks of carbon; however, peat extraction converts these systems into large and persistent sources of greenhouse gases. Although rewetting and restoration following peat extraction have taken place over the last several decades, very few studies have investigated the longer term impact of this restoration on peatland carbon balance. We determined the annual carbon balance of a former horticulturally-extracted peatland restored 10 yr prior to the study and compared these values to the carbon balance measured at neighboring unrestored and natural sites. Carbon dioxide (CO2 and methane (CH4 fluxes were measured using the chamber technique biweekly during the growing season from May to October 2010 and three times over the winter period. Dissolved organic carbon (DOC export was measured from remnant ditches in the unrestored and restored sites. During the growing season the restored site had greater uptake of CO2 than the natural site when photon flux density was greater than 1000 μmol m−2 s−1, while the unrestored site remained a source of CO2. Ecosystem respiration was similar between natural and restored sites, which were both significantly lower than the unrestored site. Methane flux remained low at the restored site except from open water pools, created as part of restoration, and remnant ditches. Export of DOC during the growing season was 5.0 and 28.8 g m−2 from the restored and unrestored sites, respectively. Due to dry conditions during the study year all sites acted as net carbon sources with annual balance of the natural, restored and unrestored sites of 250.7, 148.0 and 546.6 g C m−2, respectively. Although hydrological conditions and vegetation community at the restored site remained intermediate between natural and unrestored conditions, peatland restoration resulted in a large reduction in annual carbon loss from the system resulting in a carbon balance more similar to a natural

  11. Nanoscale Soldering of Positioned Carbon Nanotubes using Highly Conductive Electron Beam Induced Gold Deposition

    DEFF Research Database (Denmark)

    Madsen, Dorte Nørgaard; Mølhave, Kristian; Mateiu, Ramona Valentina;

    2003-01-01

    We have developed an in-situ method for controlled positioning of carbon nanotubes followed by highly conductive contacting of the nanotubes, using electron beam assisted deposition of gold. The positioning and soldering process takes place inside an Environmental Scanning Electron Microscope (E...... in a carbon matrix. Nanoscale soldering of multi-walled carbon nanotubes (MWNT) onto microelectrodes was achieved by deposition of a conducting gold line across a contact point between nanotube and electrode. The solderings were found to be mechanically stronger than the carbon nanotubes. We have positioned...

  12. Geant4 Simulation Study of Dose Distribution and Energy Straggling for Proton and Carbon Ion Beams in Water

    Directory of Open Access Journals (Sweden)

    Zhao Qiang

    2016-01-01

    Full Text Available Dose distribution and energy straggling for proton and carbon ion beams in water are investigated by using a hadrontherapy model based on the Geant4 toolkit. By gridding water phantom in N×N×N voxels along X, Y and Z axes, irradiation dose distribution in all the voxels is calculated. Results indicate that carbon ion beams have more advantages than proton beams. Proton beams have bigger width of the Bragg peak and broader lateral dose distribution than carbon ion beams for the same position of Bragg peaks. Carbon ion has a higher local ionization density and produces more secondary electrons than proton, so carbon ion beams can achieve a higher value of relative biological effectiveness.

  13. Carbon beam extraction with 14.5 GHz electron cyclotron resonance ion source at Korea Atomic Energy Research Institute

    Science.gov (United States)

    Lee, Cheol Ho; Oh, Byung-Hoon; Chang, Dae-Sik; Jeong, Sun-Chan

    2014-02-01

    A 14.5 GHz Electron Cyclotron Resonance ion source (ECRIS) has been made to produce C4+ beam for using a carbon therapy facility and recently tested at KAERI. Highly charged carbon ions have been successfully extracted. When using only CO2 gas, the beam current of C4+ was almost 14 μA at 15 kV extraction voltage. To get higher current of the C4+ beam, while optimizing confinement magnetic field configuration (e.g., axial strengths at minimum and extraction side), gas-mixing (CO2/He), and biased disk were introduced. When the gas mixing ratio of the CO2/He gas is 1:8 at an operational pressure of 5 × 10-7 mbar and the disk was biased to -150 V relative to the ion source body, the highest current of the C4+ beam was achieved to be 50 μA, more than three times higher than previously observed only with CO2 gas. Some details on the operating conditions of the ECRIS were discussed.

  14. Cancer stem cells: The potential of carbon ion beam radiation and new radiosensitizers (Review).

    Science.gov (United States)

    Baek, Sung-Jae; Ishii, Hideshi; Tamari, Keisuke; Hayashi, Kazuhiko; Nishida, Naohiro; Konno, Masamitsu; Kawamoto, Koichi; Koseki, Jun; Fukusumi, Takahito; Hasegawa, Shinichiro; Ogawa, Hisataka; Hamabe, Atsushi; Miyo, Masaaki; Noguchi, Kozo; Seo, Yuji; Doki, Yuichiro; Mori, Masaki; Ogawa, Kazuhiko

    2015-11-01

    Cancer stem cells (CSCs) are a small population of cells in cancer with stem-like properties such as cell proliferation, multiple differentiation and tumor initiation capacities. CSCs are therapy-resistant and cause cancer metastasis and recurrence. One key issue in cancer therapy is how to target and eliminate CSCs, in order to cure cancer completely without relapse and metastasis. To target CSCs, many cell surface markers, DNAs and microRNAs are considered as CSC markers. To date, the majority of the reported markers are not very specific to CSCs and are also present in non-CSCs. However, the combination of several markers is quite valuable for identifying and targeting CSCs, although more specific identification methods are needed. While CSCs are considered as critical therapeutic targets, useful treatment methods remain to be established. Epigenetic gene regulators, microRNAs, are associated with tumor initiation and progression. MicroRNAs have been recently considered as promising therapeutic targets, which can alter the therapeutic resistance of CSCs through epigenetic modification. Moreover, carbon ion beam radiotherapy is a promising treatment for CSCs. Evidence indicates that the carbon ion beam is more effective against CSCs than the conventional X-ray beam. Combination therapies of radiosensitizing microRNAs and carbon ion beam radiotherapy may be a promising cancer strategy. This review focuses on the identification and treatment resistance of CSCs and the potential of microRNAs as new radiosensitizers and carbon ion beam radiotherapy as a promising therapeutic strategy against CSCs. PMID:26330103

  15. Strong Metal-Support Interaction: Growth of Individual Carbon Nanofibers from Amorphous Carbon Interacting with an Electron Beam

    DEFF Research Database (Denmark)

    Zhang, Wei; Kuhn, Luise Theil

    2013-01-01

    The article discusses the growth behavior of carbon nanofibers (CNFs). It mentions that CNFs can be synthesized using methods such as arc-discharge, laser ablation and chemical vapor deposition. It further states that CNFs can be grown from a physical mixing of amorphous carbon and CGO/Ni nanopar......The article discusses the growth behavior of carbon nanofibers (CNFs). It mentions that CNFs can be synthesized using methods such as arc-discharge, laser ablation and chemical vapor deposition. It further states that CNFs can be grown from a physical mixing of amorphous carbon and CGO....../Ni nanoparticles, devoid of any gaseous carbon source and external heating and stimulated by an electron beam in a 300 kilo volt transmission electron microscope....

  16. Average Frequency – RA Value for Reinforced Concrete Beam Strengthened with Carbon Fibre Sheet

    Directory of Open Access Journals (Sweden)

    Mohamad M. Z.

    2016-01-01

    Full Text Available Acoustic Emission (AE is one of the tools that can be used to detect the crack and to classify the type of the crack of reinforced concrete (RC structure. Dislocation or movement of the material inside the RC may release the transient elastic wave. In this situation, AE plays important role whereby it can be used to capture the transient elastic wave and convert it into AE parameters such as amplitude, count, rise time and duration. Certain parameter can be used directly to evaluate the crack behavior. But in certain cases, the AE parameter needs to add and calculate by using related formula in order to observe the behavior of the crack. Using analysis of average frequency and RA value, the crack can be classified into tensile or shear cracks. In this study, seven phases of increasing static load were used to observe the crack behavior. The beams were tested in two conditions. For the first condition, the beams were tested in original stated without strengthened with carbon fibre sheet (CFS at the bottom of the beam or called as tension part of the beam. For the second condition, the beams were strengthened with CFS at the tension part of the beam. It was found that, beam wrapped with CFS enhanced the strength of the beams in term of maximum ultimate load. Based on the relationship between average frequency (AF and RA value, the cracks of the beams can be classified.

  17. Advanced Electron Beam Ion Sources (EBIS) for 2-nd generation carbon radiotherapy facilities

    International Nuclear Information System (INIS)

    In this work we analyze how advanced Electron Beam Ion Sources (EBIS) can facilitate the progress of carbon therapy facilities. We will demonstrate that advanced ion sources enable operation of 2-nd generation ion beam therapy (IBT) accelerators. These new accelerator concepts with designs dedicated to IBT provide beams better suited for therapy and, are more cost efficient than contemporary IBT facilities. We will give a sort overview of the existing new IBT concepts and focus on those where ion source technology is the limiting factor. We will analyse whether this limitation can be overcome in the near future thanks to ongoing EBIS development

  18. Analysis of the strength and stiffness of timber beams reinforced with carbon fiber and glass fiber

    Directory of Open Access Journals (Sweden)

    Juliano Fiorelli

    2003-06-01

    Full Text Available An experimental analysis of pinewood beams (Pinus caribea var hondurensis reinforced with glass and/or carbon fibers is discussed. The theoretical model employed to calculate the beam's bending strength takes into account the timber's ultimate limit states of tensile strength and failure by compression, considering a model of fragile elastic tension and plastic elastic compression. The validity of the theoretical model is confirmed by a comparison of the theoretical and experimental results, while the efficiency of the fiber reinforcement is corroborated by the increased strength and stiffness of the reinforced timber beams.

  19. Comparison of methods for the quantification of carbonate carbon in atmospheric PM10 aerosol samples

    Science.gov (United States)

    Jankowski, Nicole; Schmidl, Christoph; Marr, Iain L.; Bauer, Heidi; Puxbaum, Hans

    Carbonate carbon (CC) represents an important fraction of atmospheric PM10 along with organic carbon (OC) and elemental carbon (EC), if specific sources (e.g. street abrasion, construction sites, desert dust) contribute to its composition. However, analytical methods for an easy and unambiguous determination of CC in atmospheric aerosols collected on filter matrices are scarce. We propose here a method for the determination of CC based on a heating pretreatment of the sample to remove OC and EC, followed by a total carbon determination to measure CC. This procedure is used for the correction of EC also determined by a heating pretreatment (Cachier, H., Bremond, M.P., Buat-Ménard, P., 1989. Determination of atmospheric soot carbon with a simple thermal method. Tellus 41B, 379-390) but without previous HCl fumigation, as proposed. Comparison of the carbon remaining after the proposed thermal treatment at 460 °C for 60 min in an oxygen stream showed good correlation for the carbonate carbon derived by calculation from the ionic balance for ambient air and street dust samples. Using the "three step" combustion technique it is now possible to determine OC, EC and CC by the use of a TC analyser in the concentration range of 2-200 μg carbon per sample aliquot, with good precision (3-5% RSD for TC and 5-10% for CC) and accuracy. In ambient air samples from a sampling site in Vienna with elevated PM10 levels ("Liesing") CC values as high as 25% of TC and 27% CO 32-; for street dust samples 32% of TC and 25% CO 32- of total PM10 mass were observed.

  20. Design and analysis of automotive carbon fiber composite bumper beam based on finite element analysis

    Directory of Open Access Journals (Sweden)

    Tie Wang

    2015-06-01

    Full Text Available In this article, the most important part of the automotive front bumper system, namely, the bumper beam, is studied by changing the material and thickness to improve the crashworthiness performance in low-velocity impact. According to the low-speed standard of automotives stated in E.C.E. United Nations Agreement, Regulation no. 42, the low-velocity impact simulation based on finite element analysis is carried out. Lightweight is the main purpose of this article. First, the bumper beam analysis is accomplished for carbon fiber composite and steel material to analyze their deformation, weight, impact force, energy absorption, and the acceleration of the impactor. As a consequence, the bumper beam made by carbon fiber composite achieves better impact behavior. Second, on the purpose of lightweight, the bumper beams of different thickness including 5.4, 6, 6.6, and 7.2 mm are investigated. The results show that the 5.4 mm bumper beam is the best selection without sacrificing the impact performance. Third, according to the stress distribution, the thickness distribution of the bumper beam is changed to get better lightweight results. It is indicated that the weight of the improved bumper beam is further reduced and the impact performance is not weakened.

  1. Beam asymmetry Σ in π0 photoproduction off protons bound in carbon nuclei

    International Nuclear Information System (INIS)

    In order to study the dynamics of the inner components of the nucleon, its excitation spectrum is investigated through meson-photoproduction. Due to the strong overlap of the nucleon's excited states, it is insufficient to determine the cross section only. To identify all resonance contributions unambiguously, single and double polarization observables have to be measured. At the Crystal Barrel experiment at ELSA in Bonn, this is achieved utilizing linearly or circularly polarized photons and longitudinally or transversely polarized nucleons. Polarized protons are realized in a butanol target, which consists of hydrogen, oxygen and carbon. A pure carbon target was used to perform a background measurement. The results for the beam asymmetry Σ in π0 photoproduction, obtained with a carbon target and a linearly polarized photon beam, are presented. Furthermore, the influence of carbon background on the measured polarization observables is discussed.

  2. Reinforcement of timber beams with carbon fibers reinforced plastics

    Science.gov (United States)

    Gugutsidze, G.; Draškovič, F.

    2010-06-01

    Wood is a polymeric material with many valuable features and which also lacks some negative features. In order to keep up with high construction rates and the minimization of negative effects, wood has become one of the most valuable materials in modern engineering. But the use of timber material economically is also an actual problem in order to protect the environment and improve natural surroundings. A panel of scientists is interested in solving these problems and in creating rational structures, where timber can be used efficiently. These constructions are as follows: glue-laminated (gluelam), composed and reinforced wooden constructions. Composed and reinforced wooden constructions are examined less, but according to researches already carried out, it is clear that significant work can be accomplished in creating rational, highly effective and economic timber constructions. The paper deals with research on the formation of composed fiber-reinforced beams (CFRP) made of timber and provide evidence of their effectiveness. The aim of the paper is to investigate cross-bending of CFRP-reinforced gluelaminated timber beams. According to the results we were able to determine the additional effectiveness of reinforcement with CFRP (which depends on the CFRP material's quality, quantity and module of elasticity) on the mechanical features of timber and a whole beam.

  3. Experimental control of the beam properties of laser-accelerated protons and carbon ions

    Energy Technology Data Exchange (ETDEWEB)

    Amin, Munib

    2008-12-15

    The laser generation of energetic high quality beams of protons and heavier ions has opened up the door to a plethora of applications. These beams are usually generated by the interaction of a short pulse high power laser with a thin metal foil target. They could already be applied to probe transient phenomena in plasmas and to produce warm dense matter by isochoric heating. Other applications such as the production of radioisotopes and tumour radiotherapy need further research to be put into practice. To meet the requirements of each application, the properties of the laser-accelerated particle beams have to be controlled precisely. In this thesis, experimental means to control the beam properties of laser-accelerated protons and carbon ions are investigated. The production and control of proton and carbon ion beams is studied using advanced ion source designs: Experiments concerning mass-limited (i.e. small and isolated) targets are conducted. These targets have the potential to increase both the number and the energy of laser-accelerated protons. Therefore, the influence of the size of a plane foil target on proton beam properties is measured. Furthermore, carbon ion sources are investigated. Carbon ions are of particular interest in the production of warm dense matter and in cancer radiotherapy. The possibility to focus carbon ion beams is investigated and a simple method for the production of quasi-monoenergetic carbon ion beams is presented. This thesis also provides an insight into the physical processes connected to the production and the control of laser-accelerated ions. For this purpose, laser-accelerated protons are employed to probe plasma phenomena on laser-irradiated targets. Electric fields evolving on the surface of laser-irradiated metal foils and hollow metal foil cylinders are investigated. Since these fields can be used to displace, collimate or focus proton beams, understanding their temporal and spatial evolution is crucial for the design of

  4. Geant4 simulation for a study of a possible use of carbon ion pencil beams for the treatment of ocular melanomas with the active scanning system at CNAO

    Science.gov (United States)

    Farina, E.; Piersimoni, P.; Riccardi, C.; Rimoldi, A.; Tamborini, A.; Ciocca, M.

    2015-12-01

    The aim of this work was to study a possible use of carbon ion pencil beams (delivered with active scanning modality) for the treatment of ocular melanomas at the Centro Nazionale di Adroterapia Oncologica (CNAO). The promising aspect of carbon ions radiotherapy for the treatment of this disease lies in its superior relative radio-biological effectiveness (RBE). The Monte Carlo (MC) Geant4 10.00 toolkit was used to simulate the complete CNAO extraction beamline, with the active and passive components along it. A human eye modeled detector, including a realistic target tumor volume, was used as target. Cross check with previous studies at CNAO using protons allowed comparisons on possible benefits on using such a technique with respect to proton beams. Experimental data on proton and carbon ion beams transverse distributions were used to validate the simulation.

  5. Electron beam welding of 180 MM thick 15 CD 9 10 steel

    International Nuclear Information System (INIS)

    In the context of heavy component welding for the nuclear industry, an electron beam weldability study was undertaken on 180 mn thick 15 CD 9 10 (21/4 Cr-1-1 Mo) steel plates. The purpose of this study, performed using the CEA/STA 100 kW electron beam welding facilities, was to determine the welding parameters assuring sound weld beads during nominal conditions and to assess the electron beam weldability of this grade of steel in the event of very thick plates. This paper describes the procedure adopted to determine the welding parameters and gives an initial metallurgical characterization of the welds obtained for as-welded and stress-relieved states. The study confirms the operating feasibility of electron beam welding on 180 mn thick 15 CD 9.10 steel plates, during nominal conditions. However, problems related to beam start and extinction are disregarded, as are those concerning magnetic remanence. The effects on weld beam compactness of variations in the welding parameters were analyzed. Acceptable latitudes amply suffice in most cases to ensure satisfactory result reproducibility. The beam circular vibratory amplitude would appear to be a highly sensitive welding parameter. The HAZ cooling rate, the microstructure obtained consisting mainly of martensite and the hardness values measured in both heat-affected and fusion zones (high for as-welded states and leveled after stress-relieving) lead us to expect satisfactory mechanical properties for these welds. (authors). 4 refs., 6 figs

  6. Dosimetric characterization of a microDiamond detector in clinical scanned carbon ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Marinelli, Marco; Prestopino, G., E-mail: giuseppe.prestopino@uniroma2.it; Verona, C.; Verona-Rinati, G. [INFN—Dipartimento di Ingegneria Industriale, Università di Roma “Tor Vergata,” Via del Politecnico 1, Roma 00133 (Italy); Ciocca, M.; Mirandola, A.; Mairani, A. [Fondazione CNAO, Strada Campeggi 53, Pavia 27100 (Italy); Raffaele, L. [INFN—Laboratori Nazionali del Sud, Via S. Sofia 62, Catania 95123, Italy and Fondazione CNAO, Strada Campeggi 53, Pavia 27100 (Italy); Magro, G. [INFN—Dipartimento di Fisica, Università degli Studi di Pavia, Via U. Bassi 6, Pavia 27100, Italy and Fondazione CNAO, Strada Campeggi 53, Pavia 27100 (Italy)

    2015-04-15

    Purpose: To investigate for the first time the dosimetric properties of a new commercial synthetic diamond detector (PTW microDiamond) in high-energy scanned clinical carbon ion beams generated by a synchrotron at the CNAO facility. Methods: The detector response was evaluated in a water phantom with actively scanned carbon ion beams ranging from 115 to 380 MeV/u (30–250 mm Bragg peak depth in water). Homogeneous square fields of 3 × 3 and 6 × 6 cm{sup 2} were used. Short- and medium-term (2 months) detector response stability, dependence on beam energy as well as ion type (carbon ions and protons), linearity with dose, and directional and dose-rate dependence were investigated. The depth dose curve of a 280 MeV/u carbon ion beam, scanned over a 3 × 3 cm{sup 2} area, was measured with the microDiamond detector and compared to that measured using a PTW Advanced Markus ionization chamber, and also simulated using FLUKA Monte Carlo code. The detector response in two spread-out-Bragg-peaks (SOBPs), respectively, centered at 9 and 21 cm depths in water and calculated using the treatment planning system (TPS) used at CNAO, was measured. Results: A negligible drift of detector sensitivity within the experimental session was seen, indicating that no detector preirradiation was needed. Short-term response reproducibility around 1% (1 standard deviation) was found. Only 2% maximum variation of microDiamond sensitivity was observed among all the evaluated proton and carbon ion beam energies. The detector response showed a good linear behavior. Detector sensitivity was found to be dose-rate independent, with a variation below 1.3% in the evaluated dose-rate range. A very good agreement between measured and simulated Bragg curves with both microDiamond and Advanced Markus chamber was found, showing a negligible LET dependence of the tested detector. A depth dose curve was also measured by positioning the microDiamond with its main axis oriented orthogonally to the beam

  7. Quasi-steady carbon plasma source for neutral beam injector.

    Science.gov (United States)

    Koguchi, H; Sakakita, H; Kiyama, S; Shimada, T; Sato, Y; Hirano, Y

    2014-02-01

    Carbon plasma is successfully sustained during 1000 s without any carrier gas in the bucket type ionization chamber with cusp magnetic field. Every several seconds, seed plasmas having ∼3 ms duration time are injected into the ionization chamber by a shunting arch plasma gun. The weakly ionized carbon plasma ejected from the shunting arch is also ionized by 2.45 GHz microwave at the electron cyclotron resonance surface and the plasma can be sustained even in the interval of gun discharges. Control of the gun discharge interval allows to keep high pressure and to sustain the plasma for long duration.

  8. Quasi-steady carbon plasma source for neutral beam injector

    International Nuclear Information System (INIS)

    Carbon plasma is successfully sustained during 1000 s without any carrier gas in the bucket type ionization chamber with cusp magnetic field. Every several seconds, seed plasmas having ∼3 ms duration time are injected into the ionization chamber by a shunting arch plasma gun. The weakly ionized carbon plasma ejected from the shunting arch is also ionized by 2.45 GHz microwave at the electron cyclotron resonance surface and the plasma can be sustained even in the interval of gun discharges. Control of the gun discharge interval allows to keep high pressure and to sustain the plasma for long duration

  9. Quasi-steady carbon plasma source for neutral beam injector.

    Science.gov (United States)

    Koguchi, H; Sakakita, H; Kiyama, S; Shimada, T; Sato, Y; Hirano, Y

    2014-02-01

    Carbon plasma is successfully sustained during 1000 s without any carrier gas in the bucket type ionization chamber with cusp magnetic field. Every several seconds, seed plasmas having ∼3 ms duration time are injected into the ionization chamber by a shunting arch plasma gun. The weakly ionized carbon plasma ejected from the shunting arch is also ionized by 2.45 GHz microwave at the electron cyclotron resonance surface and the plasma can be sustained even in the interval of gun discharges. Control of the gun discharge interval allows to keep high pressure and to sustain the plasma for long duration. PMID:24593646

  10. ELECTRO-THERMAL EFFECTS AND DEFORMATION RESPONSE OF CARBON FIBER MAT CEMENT BEAMS

    Institute of Scientific and Technical Information of China (English)

    ZhuSirong; LiZhuoqiu; SongXianhui

    2003-01-01

    A carbon fiber mat is a sheet composed of intercrossing short carbon fibers, which has more stable and lower electrical resistivity compared with dispersed short carbon fiber mixed in cement. Thereby carbon fiber mat cement could exhibit obvious electro-thermal effect. When electrified, the temperature of composite structures made up of cement mortar and carbon fiber mat will rise rapidly. If the temperature field is not uniform, temperature difference will cause structures to deform, which can be used to adjust the deformation of structures. The temperature field and deformation response driven by the electro-thermal effects of a type of carbon fiber mat cement beams are studied. Firstly, the temperature and deformation responses are studied using theories of thermal conduction and elasticity. Secondly, experimental results are given to verify the theoretical solution. These two parts lay the foundation for temperature and deformation adjustment.

  11. DNA damage response signaling in lung adenocarcinoma A549 cells following gamma and carbon beam irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, Somnath [Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085 (India); Narang, Himanshi, E-mail: himinarang@gmail.com [Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085 (India); Sarma, Asitikantha [Radiation Biology Laboratory, Inter University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi 110 067 (India); Krishna, Malini [Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085 (India)

    2011-11-01

    Carbon beams (5.16 MeV/u, LET = 290 keV/{mu}m) are high linear energy transfer (LET) radiation characterized by higher relative biological effectiveness than low LET radiation. The aim of the current study was to determine the signaling differences between {gamma}-rays and carbon ion-irradiation. A549 cells were irradiated with 1 Gy carbon or {gamma}-rays. Carbon beam was found to be three times more cytotoxic than {gamma}-rays despite the fact that the numbers of {gamma}-H2AX foci were same. Percentage of cells showing ATM/ATR foci were more with {gamma}-rays however number of foci per cell were more in case of carbon irradiation. Large BRCA1 foci were found in all carbon irradiated cells unlike {gamma}-rays irradiated cells and prosurvival ERK pathway was activated after {gamma}-rays irradiation but not carbon. The noteworthy finding of this study is the early phase apoptosis induction by carbon ions. In the present study in A549 lung adenocarcinoma, authors conclude that despite activation of same repair molecules such as ATM and BRCA1, differences in low and high LET damage responses might be due to their distinct macromolecular complexes rather than their individual activation and the activation of cytoplasmic pathways such as ERK, whether it applies to all the cell lines need to be further explored.

  12. Reactions of carbon atoms in pulsed molecular beams

    Energy Technology Data Exchange (ETDEWEB)

    Reisler, H. [Univ. of Southern California, Los Angeles (United States)

    1993-12-01

    This research program consists of a broad scope of experiments designed to unravel the chemistry of atomic carbon in its two spin states, P and D, by using well-controlled initial conditions and state-resolved detection of products. Prerequisite to the proposed studies (and the reason why so little is known about carbon atom reactions), is the development of clean sources of carbon atoms. Therefore, in parallel with the studies of its chemistry and reaction dynamics, the authors continuously explore new, state-specific and efficient ways of producing atomic carbon. In the current program, C({sup 3}P) is produced via laser ablation of graphite, and three areas of study are being pursued: (i) exothermic reactions with small inorganic molecules (e.g., O{sub 2}, N{sub 2}O, NO{sub 2}) that can proceed via multiple pathways; (ii) the influence of vibrational and translational energy on endothermic reactions involving H-containing reactants that yield CH products (e.g., H{sub 2}O H{sub 2}CO); (iii) reactions of C({sup 3}P) with free radicals (e.g., HCO, CH{sub 3}O). In addition, the authors plan to develop a source of C({sup 1}D) atoms by exploiting the pyrolysis of diazotetrazole and its salts in the ablation source. Another important goal involves collaboration with theoreticians in order to obtain relevant potential energy surfaces, rationalize the experimental results and predict the roles of translational and vibrational energies.

  13. Interfacial electrical properties of ion-beam sputter deposited amorphous carbon on silicon

    Science.gov (United States)

    Khan, A. A.; Woollam, J. A.; Chung, Y.; Banks, B.

    1983-01-01

    Amorphous, 'diamond-like' carbon films have been deposited on Si substrates, using ion-beam sputtering. The interfacial properties are studied using capacitance and conductance measurements. Data are analyzed using existing theories for interfacial electrical properties. The density of electronic states at the interface, along with corresponding time constants are determined.

  14. Influence of electron beam irradiation on physicochemical properties of poly(trimethylene carbonate)

    NARCIS (Netherlands)

    Jozwiakowska, Joanna; Wach, Radoslaw A.; Rokita, Bozena; Ulanski, Piotr; Nalawade, Sameer P.; Grijpma, Dirk W.; Feijen, Jan; Rosiak, Janusz M.

    2011-01-01

    Electron beam (EB) irradiation of poly(trimethylene carbonate) (PTMC), an amorphous, biodegradable polymer used in the field of biomaterials, results in predominant cross-linking and finally in the formation of gel fraction, thus enabling modification of physicochemical properties of this material w

  15. Morphological and structural modifications of multiwalled carbon nanotubes by electron beam irradiation

    Science.gov (United States)

    Elsehly, Emad M.; Chechenin, N. G.; Makunin, A. V.; Motaweh, H. A.

    2016-10-01

    Effects of electron beam irradiation on a morphology and structure of multiwalled carbon nanotubes sample in a normal imaging regime of a scanning electron microscope (SEM) were investigated. Direct SEM observations give evidence that irradiation by electron beam in SEM eliminates morphological unevenness, in the form of round spots of white contrast, on the surface of carbon nanotubes (CNTs) and makes the tubes thinner. Electron dispersive analysis and Raman spectroscopy are used to explore the origin and nature of these spots. From this analysis we found that e-beam irradiation improves the CNTs graphitization. The synergy of thermal heating and ionization produced by the irradiation are discussed as possible mechanisms of the observed effects.

  16. Making junctions between carbon nanotubes using an ion beam

    CERN Document Server

    Krasheninnikov, A V; Keinonen, J; Banhart, F

    2003-01-01

    Making use of empirical potential molecular dynamics, we study ion bombardment of crossed single-walled carbon nanotubes as a tool to join the nanotubes. We demonstrate that ion irradiation should result in welding of crossed nanotubes, both suspended and deposited on substrates. We further predict optimum ion doses and energies for ion-mediated nanotube welding which may potentially be used for developing complicated networks of joined nanotubes.

  17. Design of optic system for 500 keV/10 mA electron beam machine

    International Nuclear Information System (INIS)

    In the 1995/1996 Research Year design of Electron Beam Machine components i.e. : Electron Source, High Voltage Supply, Accelerator Tube, Focussing System, Steering System, Scanning System, Vacuum System, Radiation Facility and Conveyer System also Electronics and Control System was carried out. This paper describes the design of Focussing, Steering and Scanning System. The Focussing System was an iron sheathed solenoid the Steering System was two sets of electromagnet placed perpendicular each other and the Scanning System was a set of alternating current electromagnet. The first Focussing System was designed to have 1 m focus distance for electron beam of 10 keV energy the second Focussing System was designed to have 1 m focus distance for electron beam of 1 MeV energy, the Steering System was designed to have 30o deflection angle for electron beam of 1 MeV energy and the Scanning System was designed to have 120 cm deflection distance and 20o deflection angle for electron beam of 1 MeV. Using these systems the 500 keV/10 mA Electron Beam Machine could be controlled. (author)

  18. The RHIC p-Carbon CNI Polarimeter Upgrade For The Beam Polarization And Intensity Measurements

    International Nuclear Information System (INIS)

    Proton polarization measurements in the AGS and RHIC (Relativistic Heavy Ion Collider at the beam energies 24-250 GeV) are based on proton-carbon and proton-proton elastic scattering in the Coulomb Nuclear Interference (CNI) region. Polarimeter operation in the scanning mode also gives polarization profile and beam intensity profile (beam emittance) measurements. Bunch by bunch emittance measurement is a very powerful tool for machine setup. Presently, the polarization and beam intensity profile measurements (in both vertical and horizontal planes) are restricted by the long target switching time and possible target destruction during this complicated motion. The RHIC polarimeters were operated near the limit of the counting rate for present silicon strip detectors. The ongoing polarimeter upgrade for the 2009 run will address all these problems. The upgrade should allow significant reduction of the polarization measurement errors by making feasible the complete polarization measurements, which includes polarization profiles in both the horizontal and vertical planes.

  19. Effect of Electron Beam Irradiation on the Tensile Properties of Carbon Nanotubes Sheets and Yarns

    Science.gov (United States)

    Williams, Tiffany S.; Miller, Sandi G.; Baker, James S.; McCorkle, Linda S.; Meador, Michael A.

    2013-01-01

    Carbon nanotube sheets and yarns were irradiated using electron beam (e-beam) energy to determine the effect of irradiation dose on the tensile properties. Results showed that a slight change in tensile strength occurred after irradiating as-received CNT sheets for 20 minutes, and a slight decrease in tensile strength as the irradiation time approached 90 minutes. On the other hand, the addition of small molecules to the CNT sheet surface had a greater effect on the tensile properties of e-beam irradiated CNT sheets. Some functionalized CNT sheets displayed up to a 57% increase in tensile strength following 90 minutes of e-beam exposure. In addition, as-received CNT yarns showed a significant increase in tensile strength as the irradiation time increased.

  20. Experimental study on fatigue crack propagation rate of RC beam strengthened with carbon fiber laminate

    Science.gov (United States)

    Huang, Peiyan; Liu, Guangwan; Guo, Xinyan; Huang, Man

    2008-11-01

    The experimental research on fatigue crack propagation rate of reinforced concrete (RC) beams strengthened with carbon fiber laminate (CFL) is carried out by MTS system in this paper. The experimental results show that, the main crack propagation on strengthened beam can be summarized into three phases: 1) fast propagation phase; 2) steady propagation and rest phase; 3) unsteady propagation phase. The phase 2-i.e. steady propagation and rest stage makes up about 95% of fatigue life of the strengthened beam. The propagation rate of the main crack, da/dN, in phase 2 can be described by Paris formula, and the constant C and m can be confirmed by the fatigue crack propagation experiments of the RC beams strengthened with CFL under three-point bending loads.

  1. Measurement of neutral current coherent neutral pion production on carbon in a few-GeV neutrino beam

    OpenAIRE

    Kurimoto, Y; Alcaraz-Aunion, J. L.; Brice, S J; Bugel, L.; Catala-Perez, J.; Cheng, G.; Conrad, J.M.; Djurcic, Z.; Dore, U.; Finley, D. A.; Franke, A. J.; C. Giganti; Gomez-Cadenas, J. J.; Guzowski, P.; Hanson, A.

    2010-01-01

    The SciBooNE Collaboration reports a measurement of neutral current coherent neutral pion production on carbon by a muon neutrino beam with average energy 0.8 GeV. The separation of coherent from inclusive neutral pion production has been improved by detecting recoil protons from resonant neutral pion production. We measure the ratio of the neutral current coherent neutral pion production to total charged current cross sections to be (1.16 +/- 0.24) x 10-2. The ratio of charged current cohere...

  2. Hardness and stress of amorphous carbon film deposited by glow discharge and ion beam assisting deposition

    CERN Document Server

    Marques, F C

    2000-01-01

    The hardness and stress of amorphous carbon films prepared by glow discharge and by ion beam assisting deposition are investigated. Relatively hard and almost stress free amorphous carbon films were deposited by the glow discharge technique. On the other hand, by using the ion beam assisting deposition, hard films were also obtained with a stress of the same order of those found in tetrahedral amorphous carbon films. A structural analysis indicates that all films are composed of a sp sup 2 -rich network. These results contradict the currently accepted concept that both stress and hardness are only related to the concentration of sp sup 3 sites. Furthermore, the same results also indicate that the sp sup 2 sites may also contribute to the hardness of the films.

  3. Intense heavy ion beam-induced temperature effects in carbon-based stripper foils

    International Nuclear Information System (INIS)

    At the future FAIR facility, reliably working solid carbon stripper foils are desired for providing intermediate charge states to SIS18. With the expected high beam intensities, the foils experience enhanced degradation and limited lifetime due to severe radiation damage, stress waves, and thermal effects. This work presents systematic measurements of the temperature of different carbon-based stripper foils (amorphous, diamond-like, and carbon-nanotube based) exposed to 4.8 MeV/u U, Bi, and Au beams of different pulse intensities. Thermal and spectroscopic analyses were performed by means of infrared thermography and Fourier transform infrared spectroscopy. The resulting temperature depends on the foil thickness and strongly increases with increasing pulse intensity and repetition rate. (author)

  4. Experimental studies of superhard materials carbon nitride CNx prepared by ion-beam synthesis method

    Institute of Scientific and Technical Information of China (English)

    辛火平; 林成鲁; 许华平; 邹世昌; 石晓红; 吴兴龙; 朱宏; P.L.FHemment

    1996-01-01

    Formation of superhard materials carbon nitride CNt by using ion-beam synthesis method is reported.100-keV high-dose N+ ions were implanted into carbon thin films at different temperatures.The samples were evaluated by X-ray photoelectron spectroscopy (XPS),Fourier transformation-infrared absorption spectroscopy (FTIR),Raman spectroscopy,cross-sectional transmission electron microscopy (XTEM),Rutherford backscattering spectroscopy (RBS).X-ray diffraction analysis (XRD) and Vickers microhardness measurement.The results show that the buried carbon nitride CN> layer has been successfully formed by using 100-keV high-dose N+ ions implantation into carbon thin film.Implantation of reactive ions into silicon (IRIS) computer program has been used to simulate the formation of the buried β-C3N4 layer as N+ ions are implanted into carbon.A good agreement between experimental measurements and IRIS simulation is found.

  5. Establishment of the method for profile evaluation in matter using the therapeutic carbon pencil beam

    International Nuclear Information System (INIS)

    The scanning irradiation of the pencil beam is superior in comparison to the conventional extended-field irradiation in dose concentration. The carbon pencil beam spreads its profile in matter. The factors that cause the profile change are the nuclear fragmentation reactions and the multiple Coulomb scatterings. The fragmentation reaction is a type of nuclear reactions, where the high-energy incident particles interact with target nuclei and fragment the incident particles themselves or the target nucleus. In order to improve the accuracy of the treatment planning for the carbon beam, it is necessary to evaluate quantitatively the effect of the nuclear fragmentation reactions. The objective of this study is to establish the evaluation method for the carbon pencil beam profile in matter by selectively acquiring the nuclear fragmentation reactions and the multiple Coulomb scattering. This experiment was proposed to carry out in three years. Events with the nuclear fragmentation reactions and the multiple Coulomb scatterings were separately identified by a dedicated detector devised by our group. Profiles of these events were successfully measured. (author)

  6. Vacuum performance of a carbon fibre cryosorber for the LHC LSS beam screen

    CERN Document Server

    Anashin, V V; Dostovalov, R V; Korotaeva, Z A; Krasnov, A A; Malyshev, O B; Poluboyarov, V A

    2004-01-01

    A new carbon fibre material was developed at the Institute of Solid State Chemistry and Mechanochemistry at the Siberian Branch of the Russian Academy of Science (SB RAS) to meet the large hadron collider (LHC) vacuum chamber. The material must have a large sorbing capacity, a certain pumping speed, a working temperature range between 5 and 20K, a low activation temperature (below room temperature), a certain size in order to fit into the limited space available and it should be easy to mount. The vacuum parameters of the LHC vacuum chamber prototype with a carbon fibre cryosorber mounted onto the beam screen were studied in the beam screen temperature range from 14 to 25K at the Budker Institute of Nuclear Physics SB RAS. This carbon fibre material has shown sufficient sorption capacity for hydrogen at operational temperatures of the beam screen in the LHC long straight sections. It is also very important that this material does not crumble and makes a convenient fixation onto the beam screen in comparison t...

  7. Carbon-ion beams induce production of an immune mediator protein, high mobility group box 1, at levels comparable with X-ray irradiation

    International Nuclear Information System (INIS)

    X-ray radiotherapy activates tumor antigen-specific T-cell responses, and increases in the serum levels of high mobility group box 1 (HMGB1) induced by X-ray irradiation play a pivotal role in activating anti-tumor immunity. Here, we examined whether carbon-ion beams, as well as X-rays, can induce HMGB1 release from human cancer cell lines. The study examined five human cancer cell lines: TE2, KYSE70, A549, NCI-H460 and WiDr. The proportion of cells surviving X- or carbon-ion beam irradiation was assessed in a clonogenic assay. The D10, the dose at which 10% of cells survive, was calculated using a linear–quadratic model. HMGB1 levels in the culture supernatants were assessed by an ELISA. The D10 dose for X-rays in TE2, KYSE70, A549, NCI-H460 and WiDr cells was 2.1, 6.7, 8.0, 4.8 and 7.1 Gy, respectively, whereas that for carbon-ion beams was 0.9, 2.5, 2.7, 1.8 and 3.5 Gy, respectively. X-rays and carbon-ion beams significantly increased HMGB1 levels in the culture supernatants of A549, NCI-H460 and WiDr cells at 72 h post-irradiation with a D10 dose. Furthermore, irradiation with X-rays or carbon-ion beams significantly increased HMGB1 levels in the culture supernatants of all five cell lines at 96 h post-irradiation. There was no significant difference in the amount of HMGB1 induced by X-rays and carbon-ion beams at any time-point (except at 96 h for NCI-H460 cells); thus we conclude that comparable levels of HMGB1 were detected after irradiation with iso-survival doses of X-rays and carbon-ion beams. (author)

  8. Clinical output factors for carbon-ion beams passing through polyethylene

    CERN Document Server

    Kanematsu, Nobuyuki; Ogata, Risa; Himukai, Takeshi

    2013-01-01

    Purpose: A recent study suggested that polyethylene (PE) range compensators would cause extra carbon-ion attenuation by 0.45%/cm due to limitations in water equivalence. The present study aims to assess its influence on tumor dose in carbon-ion radiotherapy. Methods: Carbon-ion radiation was modeled to be composed of primary carbon ions and secondary particles. For these components, tumor dose fraction and relative biological effectiveness (RBE) were estimated at a reference depth in the middle of spread-out Bragg peak. The PE effect was estimated for clinical carbon-ion beams and was partially tested by experiment. The two-component model was integrated into a treatment-planning system, with which the PE effect on tumor dose was investigated in two clinical cases. Results: The fluence and clinical attenuation coefficients for dose decrease per polyethylene thickness were estimated to be 0.1%-0.3%/cm and 0.2%-0.4%/cm, depending on energy and modulation of clinical carbon-ion beams. In the treatment-planning s...

  9. Nano-structural Modification of Amorphous Carbon Thin Films by Low-energy Electron Beam Irradiation

    Institute of Scientific and Technical Information of China (English)

    EijiIwamura; MasanoriYamaguchi

    2004-01-01

    A new approach using a low-energy electron beam radiation system was investigated to synthesize carbon hybrid structures in amorphous carbon thin films. Two types of amorphous carbon films, which were 15at% iron containing film and with column/inter-column structures, were deposited onto Si substrates by a sputtering technique and subsequently exposed to an electron shower of which the energy and dose rate were much smaller compared to an intense electron beam used in a transmission electron microscopy. As a result of the low-energy and low-dose electron irradiation process, graphitic structures formed in amorphous matrix at a relatively low temperature up to 450 K. Hybrid carbon thin films containing onion-like structures in an amorphous carbon matrix were synthesized by dynamic structural modification of iron containing amorphous carbon thin films. It was found that the graphitization progressed more in the electron irradiation than in annealing at 773K, and it was attributed to thermal and catalytic effects which are strongly related to grain growth of metal clusters. On the other hand, a reversal of TEM image contrast was observed in a-C films with column/inter-column structures. It is presumed that preferable graphitization occurred in the inter-column regions induced by electron irradiation.

  10. Nano-structural Modification of Amorphous Carbon Thin Films by Low-energy Electron Beam Irradiation

    Institute of Scientific and Technical Information of China (English)

    Eiji Iwamura; Masanori Yamaguchi

    2004-01-01

    A new approach using a low-energy electron beam radiation system was investigated to synthesize carbon hybrid structures in amorphous carbon thin films. Two types of amorphous carbon films, which were 15at% iron containing film and with column/inter-column structures, were deposited onto Si substrates by a sputtering technique and subsequently exposed to an electron shower of which the energy and dose rate were much smaller compared to an intense electron beam used in a transmission electron microscopy. As a result of the low-energy and low-dose electron irradiation process,graphitic structures formed in amorphous matrix at a relatively low temperature up to 450 K. Hybrid carbon thin films containing onion-like structures in an amorphous carbon matrix were synthesized by dynamic structural modification of iron containing amorphous carbon thin films. It was found that the graphitization progressed more in the electron irradiation than in annealing at 773K, and it was attributed to thermal and catalytic effects which are strongly related to grain growth of metal clusters. On the other hand, a reversal of TEM image contrast was observed in a-C films with column/inter-column structures. It is presumed that preferable graphitization occurred in the inter-column regions induced by electron irradiation.

  11. Alanine Radiation Detectors in Therapeutic Carbon Ion Beams

    DEFF Research Database (Denmark)

    Herrmann, Rochus; Jäkel, Oliver; Palmans, Hugo;

    proportional to absorbed dose. A model by Hansen and Olsen, based on the Track Structure Theory is available, which can predict the relative efficiency of some detectors, when the particle spectrum is known. For alanine detectors the model was successfully validated by Hansen and Olsen for several ion species...... at energies below 20 MeV/u. We implemented this model in the Monte Carlo code FLUKA. At the GSI heavy ion facility in Darmstadt, Germany, alanine has been irradiated with carbon ions at energies between 88 an 400 MeV/u, which is the energy range used for therapy. The irradiation and the detector response have...... been simulated with FLUKA. We found an agreement between measured values of the relative efficiency with values predicted by the Hansen and Olsen model with divergence less than 4%. With the implementation in FLUKA we are able to simulate the detector response in the depth dose curves with precisions...

  12. Ultra-low-energy (<10 eV/u) ion beam bombardment effect on naked DNA

    Energy Technology Data Exchange (ETDEWEB)

    Thopan, P. [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Thongkumkoon, P. [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Prakrajang, K. [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Faculty of Science, Maejo University, Chiang Mai 50290 (Thailand); Suwannakachorn, D. [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Yu, L.D., E-mail: yuld@thep-center.org [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Thailand Center of Excellence in Physics, Commission on Higher Education, 328 Si Ayutthaya Road, Bangkok 10400 (Thailand)

    2014-05-01

    Highlights: • Decelerated ultra-low energy ion beam bombarded naked DNA. • DNA form change induced by ion bombardment was investigated. • N-ion bombardment at 32 eV induced DNA single and double strand breaks. • Ar-ion bombardment at a-few-hundreds eV induced DNA single strand break. - Abstract: Since ion energy deposition in the ion-bombarded materials dominantly occurs in the low-energy range, it is very interesting to know effects from ultra-low-energy ion interaction with DNA for understanding ion-beam-induced genetic mutation. Tens-keV Ar- and N-ion beams were decelerated to ultra-low energy ranging from 20 to 100 eV, or only a few to 10 eV/u, to bombard naked plasmid DNA. The bombarded DNA was analyzed using gel electrophoresis for DNA form changes. The original DNA supercoiled form was found to change to relaxed and linear forms, indicating single or double strand breaks after bombarded by tens-eV ion beam. N-ion beam was found more effective in inducing DNA change and mutation than Ar-ion beam. The study demonstrated that the ion bombardment with energy as low as several-tens eV was able to break DNA strands and thus potentially to cause genetic modification of biological cells. The experimental results were discussed in terms of direct atomic collision between the ions and DNA atoms.

  13. The influence of lateral beam profile modifications in scanned proton and carbon ion therapy: a Monte Carlo study

    CERN Document Server

    Parodi, K; Kraemer, M; Sommerer, F; Naumann, J; Mairani, A; Brons, S

    2010-01-01

    Scanned ion beam delivery promises superior flexibility and accuracy for highly conformal tumour therapy in comparison to the usage of passive beam shaping systems. The attainable precision demands correct overlapping of the pencil-like beams which build up the entire dose distribution in the treatment field. In particular, improper dose application due to deviations of the lateral beam profiles from the nominal planning conditions must be prevented via appropriate beam monitoring in the beamline, prior to the entrance in the patient. To assess the necessary tolerance thresholds of the beam monitoring system at the Heidelberg Ion Beam Therapy Center, Germany, this study has investigated several worst-case scenarios for a sensitive treatment plan, namely scanned proton and carbon ion delivery to a small target volume at a shallow depth. Deviations from the nominal lateral beam profiles were simulated, which may occur because of misaligned elements or changes of the beam optic in the beamline. Data have been an...

  14. Electron-beam heat treatment of thin band of low-carbon steel

    International Nuclear Information System (INIS)

    Using the methods of raster electron microscopy, X-ray structural and chemical analysis and also X-ray microanalysis, the change was studied in the mechanical properies of a band made of low-carbon steel 08 kp that takes place after electron-beam heat treatment. It has been shown that the above change is due to a specific character of the α reversible γ phase transition. After electron-beam treatment under optimum conditions, the properties of the band made of steel 08 kp and 0.15 mm thick (plasticity, ultimate strength, etc.) are similar to those obtained using the conventional procedures (annealing and skin pass rolling)

  15. Deposition of diamond like carbon films by using a single ion gun with varying beam source

    Institute of Scientific and Technical Information of China (English)

    JIANG Jin-qiu; Chen Zhu-ping

    2001-01-01

    Diamond like carbon films have been successfully deposited on the steel substrate, by using a single ion gun with varying beam source. The films may appear blue, yellow and transparent in color, which was found related to contaminants from the sample holder and could be avoided. The thickness of the films ranges from tens up to 200 nanometers, and the hardness is in the range 20 to 30 GPa. Raman analytical results reveal the films are in amorphous structure. The effects of different beam source on the films structure are further discussed.

  16. Raman shift on n-doped amorphous carbon thin films grown by electron beam evaporation

    Energy Technology Data Exchange (ETDEWEB)

    Rebollo P., B. [Departamento de Fisica, Pontificia Universidad Catolica de Rio de Janeiro (Brazil); Facultad de Ciencias Fisico-Matematicas, Benemerita Universidad Autonoma de Puebla (Mexico); Freire L., F. Jr. [Departamento de Fisica, Pontificia Universidad Catolica de Rio de Janeiro (Brazil); Lozada M., R.; Palomino M., R. [Facultad de Ciencias Fisico-Matematicas, Benemerita Universidad Autonoma de Puebla (Mexico); Jimenez S., S. [Centro de Investigacion y de Estudios Avanzados del IPN, Laboratorio de Investigacion en Materiales, Queretaro (Mexico); Zelaya A., O. [Centro de Investigacion y de Estudios Avanzados del IPN, Departamento de Fisica, CINVESTAV-IPN, P.O. Box 14-740, Mexico 07360 D.F. (Mexico)

    2007-04-15

    The structural properties of carbon thin films synthesized under an atmosphere of nitrogen by means of electron beam evaporation were studied by Raman scattering spectroscopy. The electron beam evaporation technique is an important alternative to grown layers of this material with interesting structural properties. The observed shift of the Raman G band shows that the structure of the films tends to become more graphitic upon the increase of the deposition time. (copyright 2007 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  17. Surface analysis and a novel application of carbon sheet pump in the GAMMA 10 tandem mirror

    International Nuclear Information System (INIS)

    Samples of carbon sheet pump (CSP) exposed to fast neutrals have been analyzed by using microscopic techniques in order to improve the performance of CSP and to examine the applicability of CSP to actual devices. It has been confirmed from the microscopic viewpoint for the first time that fast neutrals emitted from plasmas generated by the actual confinement device (GAMMA 10) are trapped by the C/C material. A numerical simulation is performed by means of the Monte Carlo simulation code TRIM (ver. TRVMC95) for the sake of the evaluation of the results obtained by elastic recoil detection technique. CSP has been newly applied to the shine-through beam dump of a neutral beam injector in order to test the pumping effect of CSP under the conditions of high heat and particle load (several MW/m2 and 2.5x1021 H/m2 s at the beam center, respectively). It also has been found from pressure-balance analysis that 80% of incident particles are trapped by CSP

  18. Off-line production of intense {sup 7,10}Be{sup +} beams

    Energy Technology Data Exchange (ETDEWEB)

    Koester, U. E-mail: ulli.koster@cern.ch; Argentini, M.; Catherall, R.; Fedoseyev, V.N.; Gaeggeler, H.W.; Jonsson, O.C.; Weinreich, R

    2003-05-01

    {sup 7}Be and {sup 10}Be were produced by 590 MeV proton bombardment of a graphite target at PSI. Parts of this graphite target were transferred into an ISOLDE target and ion source unit and ionized with the ISOLDE resonance ionization laser ion source. Thus intense radioactive ion beams of 300 nA of {sup 7,10}Be{sup +} were produced off-line.

  19. Off-line production of intense $^{7,10}Be^{+}$ beams

    CERN Document Server

    Köster, U; Catherall, R; Fedosseev, V; Gäggeler, H W; Jonsson, O C; Weinreich, R

    2003-01-01

    $^7$Be and $^{10}$Be were produced by 590~MeV proton bombardment of a graphite target at PSI. Parts of this graphite target were transferred into an ISOLDE target and ion source unit and ionized with the ISOLDE resonance ionization laser ion source (RILIS). Thus intense radioactive ion beams of 300~nA of $^{7,10}$Be$^+$ were produced off-line.

  20. Compilation of erosion yields of metal-doped carbon materials by deuterium impact from ion beam and low temperature plasma

    Energy Technology Data Exchange (ETDEWEB)

    Balden, M., E-mail: Martin.Balden@ipp.mpg.de [Max-Planck-Institut fuer Plasmaphysik, EURATOM Association, 85748 Garching (Germany); Starke, P. [Lehrstuhl fuer Experimentelle Plasmaphysik, Institut fuer Physik, Universitaet Augsburg, D-86135 Augsburg (Germany); Garcia-Rosales, C. [CEIT and Tecnun (University of Navarra), E-20018 San Sebastian (Spain); Adelhelm, C.; Sauter, P.A. [Max-Planck-Institut fuer Plasmaphysik, EURATOM Association, 85748 Garching (Germany); Lopez-Galilea, I.; Ordas, N. [CEIT and Tecnun (University of Navarra), E-20018 San Sebastian (Spain); Fernandez, J.M. Ramos; Escandell, M. Martinez [Departamento de Quimica Inorganica, University of Alicante, E-03690 Alicante (Spain)

    2011-10-01

    The erosion yield by deuterium impact was determined for various doped carbon-based materials. Ion beam bombardment with 30 and 200 eV at elevated temperatures (600-850 K) and low temperature plasma exposure with 30 eV ion energy ({approx}7 x 10{sup 20} ions/m{sup 2}s) and about 170 times higher thermal atomic deuterium flux at 300 K and 630 K were performed. The total yield of fine-grain graphites doped with 4 at.% Ti and Zr is reduced by a factor of 4 for 30 and 200 eV D impact at elevated temperatures at D fluences above 10{sup 24} m{sup -2} compared to undoped graphite. Extensive carbide particle loss can be excluded up to fluences of {approx}10{sup 25} m{sup -2}.

  1. Polarimetry diagnostic on OMEGA EP using a 10-ps, 263-nm probe beam

    Energy Technology Data Exchange (ETDEWEB)

    Davies, A., E-mail: adavies@lle.rochester.edu; Haberberger, D.; Boni, R.; Ivancic, S.; Brown, R.; Froula, D. H. [Laboratory for Laser Energetics, University of Rochester, Rochester, New York 14623 (United States)

    2014-11-15

    A polarimetry diagnostic was built and characterized for magnetic-field measurements in laser-plasma experiments on the OMEGA EP laser. This diagnostic was built into the existing 4ω (263-nm) probe system that employs a 10-ps laser pulse collected with an f/4 imaging system. The diagnostic measures the rotation of the probe beam's polarization. The polarimeter uses a Wollaston prism to split the probe beam into orthogonal polarization components. Spatially localized intensity variations between images indicate polarization rotation. Magnetic fields can be calculated by combining the polarimetry data with the measured plasma density profile obtained from angular filter refractometry.

  2. Charge equilibrium of a laser-generated carbon-ion beam in warm dense matter

    International Nuclear Information System (INIS)

    Using ion carbon beams generated by high intensity short pulse lasers we perform measurements of single shot mean charge equilibration in cold or isochorically heated solid density aluminum matter. We demonstrate that plasma effects in such matter heated up to 1 eV do not significantly impact the equilibration of carbon ions with energies 0.045-0.5 MeV/nucleon. Furthermore, these measurements allow for a first evaluation of semiempirical formulas or ab initio models that are being used to predict the mean of the equilibrium charge state distribution for light ions passing through warm dense matter. (authors)

  3. Tribological properties of ion beam deposited diamond-like carbon film on silicon nitride

    International Nuclear Information System (INIS)

    The present article reports on the physical characterization and tribological properties of diamond-like carbon (DLC) films deposited on structural Si3N4 substrates. The films were deposited by the direct ion beam deposition technique. The ion beam was produced by plasma discharge of pre-mixed methane and hydrogen gas in a Kaufman-type ion source. The deposited films were found to be amorphous and contained about 70% carbon and 30% hydrogen. The friction coefficient of an uncoated Si3N4 ball on a DLC coated Si3N4 disc starts at about 0.2, then decreases rapidly to 0.1-0.15 with increasing sliding distance. Increasing humidity results in a slight increase in friction coefficient, but a significant decrease in wear factor. The wear factor for the tests at ≅60% rh (relative humidity) are about an order of magnitude smaller than the tests at 3% rh. (orig.)

  4. Radiological characteristics of MRI-based VIP polymer gel under carbon beam irradiation

    Science.gov (United States)

    Maeyama, T.; Fukunishi, N.; Ishikawa, K. L.; Furuta, T.; Fukasaku, K.; Takagi, S.; Noda, S.; Himeno, R.; Fukuda, S.

    2015-02-01

    We study the radiological characteristics of VIP polymer gel dosimeters under carbon beam irradiation with energy of 135 and 290 AMeV. To evaluate dose response of VIP polymer gels, the transverse (or spin-spin) relaxation rate R2 of the dosimeters measured by magnetic resonance imaging (MRI) as a function of linear energy transfer (LET), rather than penetration depth, as is usually done in previous reports. LET is evaluated by use of the particle transport simulation code PHITS. Our results reveal that the dose response decreases with increasing dose-averaged LET and that the dose response-LET relation also varies with incident carbon beam energy. The latter can be explained by taking into account the contribution from fragmentation products.

  5. Consumption of carbon fiber plates in the reinforced concrete beams strengthened with CFPs

    Institute of Scientific and Technical Information of China (English)

    BU Liangtao; SONG Li; SHI Chuxian

    2007-01-01

    Four-point bending flexural tests were conducted to one full-size reinforced concrete (RC) beam and three full-size RC beams strengthened with carbon fiber plates (CFPs).The experimental results showed that the consumption of CFP had significant effects on failure modes and the flexural capacity.An analytical procedure,based on the limit failure ode and ductility,was presented to predict the applied area of CFP.An analytical program,based on Smith-Teng model and Cheng-Teng model,was provided to calculate the bonding length of CFP.The test results are used to validate the proposed procedure.The results are also applied to the design and construction of RC beam strengthened with CFP.

  6. Characterization of focused beam of desktop 10-Hz capillary-discharge 46.9-nm laser

    Science.gov (United States)

    Vyšin, Ludek; Burian, Tomás; Chalupský, Jaromír; Grisham, Michael; Hájková, Vera; Heinbuch, Scott; Jakubczak, Krzysztof; Martz, Dale; Mocek, Tomás; Pira, Peter; Polan, Jirí; Rocca, Jorge J.; Rus, Bedrich; Sobota, Jaroslav; Juha, Libor

    2009-05-01

    The desktop capillary-discharge Ne-like Ar laser (CDL) providing 10-μJ nanosecond pulses of coherent 46.9-nm radiation with a repetition rate up to 12 Hz was developed and built at the Colorado State University in Fort Collins and then installed in Prague. The beam of the laser was focused by a spherical mirror covered with Si/Sc multilayer coating onto the surface of poly(methyl methacrylate) - PMMA. Interaction parameters vary by changing the distance between sample surface and beam focus. The samples were exposed to various numbers of shots. Analysis of damaged PMMA by atomic force (AFM) and Nomarski (DIC - differential interference contrast) microscopes allows not only to determine the key characteristics of the focused beam (e.g. Rayleigh's parameter, focal spot diameter, tight focus position, etc.) but also to investigate mechanisms of the radiation-induced erosion processes.

  7. 8 and 10 MeV electron beam small field profiles through Fricke xylenol gel dosimeter

    International Nuclear Information System (INIS)

    The dose distribution evaluation along of an ionizing radiation field central axis is one of the factors that contribute to the absorbed dose accuracy in the target volume. This distribution can show specific characteristics of an electron beam as the parameters penumbra, symmetry and homogeneity (flatness), which can be depicted from beam profiles. In this work was evaluated the behavior of these parameters as a function of the electron beam energy and the field size. The Fricke Xylenol Gel (FXG) is a chemical dosimeter that has an effective atomic number of 7.75 and density of 1.05 g/cm3, near to those of soft tissue. For beam profile analysis were used: the dosimeters FXG and the ionization chamber (IC), source skin distance of 100 cm, square and circular small field sizes configurations and 8 and 10 MeV electron energies. From the obtained results one could verify that the penumbra values were higher for the higher energy and larger field sizes, while the symmetry and flatness presented variation only with the energy, being this variation for flatness almost insignificant. The parameter results for both dosimeters, present similar behaviors and values in agreement with the established tolerances. Through these results one can conclude that the FXG can be applied as dosimeter in the evaluation of parameters that characterizes clinical electron beams for small field sizes. (author)

  8. Characterization of polyacrylonitrile based carbon nanofiber mats via electron beam processing.

    Science.gov (United States)

    Kim, Du-Yeong; Shin, Hye-Kyoung; Jeun, Joon-Pyo; Kim, Hyun-Bin; Oh, Seung-Hwan; Kang, Phil-Hyun

    2012-07-01

    The aim of this study was to evaluate the ability of electron beam irradiation to drive stabilization reactions within PAN nanofiber mats to obtain carbon nanofiber mats. PAN nanofiber mats with fiber diameters of 300-400 nm were prepared via an electrospinning method. Electrospun PAN nanofiber mats were stabilized by electron beam irradiation with various doses up to 5,000 kGy. Using the irradiation-stabilized PAN nanofiber mats, carbon nanofibers were obtained by pyrolysis in a tube furnace for 1 h at 1,000 degrees C under an N2 atmosphere. FT-IR analysis indicated that the transformation of C[triple bond]N groups to C==N groups was accelerated by electron beam stabilization. The thermal behavior of the PAN nanofiber mats was studied using DSC and TGA. DSC thermograms showed that the peak temperatures of the exothermic reactions were found to decrease with increasing electron beam irradiation doses. Irradiation-stabilized PAN nanofiber mats were not observed to dramatically decrease in weight between 290 degrees C and 320 degrees C, an observation presumed to be related to cyclization. The char yields of PAN were found to increase with increasing irradiation doses. PMID:22966719

  9. Mutagenic effects of carbon ion beam irradiations on dry Lotus japonicus seeds

    Science.gov (United States)

    Luo, Shanwei; Zhou, Libin; Li, Wenjian; Du, Yan; Yu, Lixia; Feng, Hui; Mu, Jinhu; Chen, Yuze

    2016-09-01

    Carbon ion beam irradiation is a powerful method for creating mutants and has been used in crop breeding more and more. To investigate the effects of carbon ion beams on Lotus japonicus, dry seeds were irradiated by 80 MeV/u carbon ion beam at dosages of 0, 100, 200, 300, 400, 500 and 600 Gy. The germination rate, survival rate and root length of M1 populations were explored and the dose of 400 Gy was selected as the median lethal dose (LD50) for a large-scale mutant screening. Among 2472 M2 plants, 127 morphological mutants including leaf, stem, flower and fruit phenotypic variation were found, and the mutation frequency was approximately 5.14%. Inter simple sequence repeat (ISSR) assays were utilized to investigate the DNA polymorphism between seven mutants and eight plants without phenotypic variation from M2 populations. No remarkable differences were detected between these two groups, and the total polymorphic rate was 0.567%.

  10. Electrochemical impedance spectroscopy on nanostructured carbon electrodes grown by supersonic cluster beam deposition

    Energy Technology Data Exchange (ETDEWEB)

    Bettini, Luca Giacomo; Bardizza, Giorgio; Podesta, Alessandro; Milani, Paolo; Piseri, Paolo, E-mail: piseri@mi.infn.it [Universita degli Studi di Milano, Dipartimento di Fisica and CIMaINa (Italy)

    2013-02-15

    Nanostructured porous films of carbon with density of about 0.5 g/cm{sup 3} and 200 nm thickness were deposited at room temperature by supersonic cluster beam deposition (SCBD) from carbon clusters formed in the gas phase. Carbon film surface topography, determined by atomic force microscopy, reveals a surface roughness of 16 nm and a granular morphology arising from the low kinetic energy ballistic deposition regime. The material is characterized by a highly disordered carbon structure with predominant sp2 hybridization as evidenced by Raman spectroscopy. The interface properties of nanostructured carbon electrodes were investigated by cyclic voltammetry and electrochemical impedance spectroscopy employing KOH 1 M solution as aqueous electrolyte. An increase of the double layer capacitance is observed when the electrodes are heat treated in air or when a nanostructured nickel layer deposited by SCBD on top of a sputter deposited film of the same metal is employed as a current collector instead of a plain metallic film. This enhancement is consistent with an improved charge injection in the active material and is ascribed to the modification of the electrical contact at the interface between the carbon and the metal current collector. Specific capacitance values up to 120 F/g have been measured for the electrodes with nanostructured metal/carbon interface.

  11. Focused-electron-beam-induced processing (FEBIP) for emerging applications in carbon nanoelectronics

    International Nuclear Information System (INIS)

    Focused-electron-beam-induced processing (FEBIP), a resist-free additive nanomanufacturing technique, is an actively researched method for ''direct-write'' processing of a wide range of structural and functional nanomaterials, with high degree of spatial and time-domain control. This article attempts to critically assess the FEBIP capabilities and unique value proposition in the context of processing of electronics materials, with a particular emphasis on emerging carbon (i.e., based on graphene and carbon nanotubes) devices and interconnect structures. One of the major hurdles in advancing the carbon-based electronic materials and device fabrication is a disjoint nature of various processing steps involved in making a functional device from the precursor graphene/CNT materials. Not only this multi-step sequence severely limits the throughput and increases the cost, but also dramatically reduces the processing reproducibility and negatively impacts the quality because of possible between-the-step contamination, especially for impurity-susceptible materials such as graphene. The FEBIP provides a unique opportunity to address many challenges of carbon nanoelectronics, especially when it is employed as part of an integrated processing environment based on multiple ''beams'' of energetic particles, including electrons, photons, and molecules. This avenue is promising from the applications' prospective, as such a multi-functional (electron/photon/molecule beam) enables one to define shapes (patterning), form structures (deposition/etching), and modify (cleaning/doping/annealing) properties with locally resolved control on nanoscale using the same tool without ever changing the processing environment. It thus will have a direct positive impact on enhancing functionality, improving quality and reducing fabrication costs for electronic devices, based on both conventional CMOS and emerging carbon (CNT/graphene) materials. (orig.)

  12. Focused-electron-beam-induced processing (FEBIP) for emerging applications in carbon nanoelectronics

    Science.gov (United States)

    Fedorov, Andrei G.; Kim, Songkil; Henry, Mathias; Kulkarni, Dhaval; Tsukruk, Vladimir V.

    2014-12-01

    Focused-electron-beam-induced processing (FEBIP), a resist-free additive nanomanufacturing technique, is an actively researched method for "direct-write" processing of a wide range of structural and functional nanomaterials, with high degree of spatial and time-domain control. This article attempts to critically assess the FEBIP capabilities and unique value proposition in the context of processing of electronics materials, with a particular emphasis on emerging carbon (i.e., based on graphene and carbon nanotubes) devices and interconnect structures. One of the major hurdles in advancing the carbon-based electronic materials and device fabrication is a disjoint nature of various processing steps involved in making a functional device from the precursor graphene/CNT materials. Not only this multi-step sequence severely limits the throughput and increases the cost, but also dramatically reduces the processing reproducibility and negatively impacts the quality because of possible between-the-step contamination, especially for impurity-susceptible materials such as graphene. The FEBIP provides a unique opportunity to address many challenges of carbon nanoelectronics, especially when it is employed as part of an integrated processing environment based on multiple "beams" of energetic particles, including electrons, photons, and molecules. This avenue is promising from the applications' prospective, as such a multi-functional (electron/photon/molecule beam) enables one to define shapes (patterning), form structures (deposition/etching), and modify (cleaning/doping/annealing) properties with locally resolved control on nanoscale using the same tool without ever changing the processing environment. It thus will have a direct positive impact on enhancing functionality, improving quality and reducing fabrication costs for electronic devices, based on both conventional CMOS and emerging carbon (CNT/graphene) materials.

  13. Reactions with a 10Be beam to study the one-neutron halo nucleus 11Be

    Science.gov (United States)

    Jones, K. L.

    2016-07-01

    Halo nuclei are excellent examples of few-body systems consisting of a core and weakly-bound halo nucleons. Where there is only one nucleon in the halo, as in 11Be, the many-body problem can be reduced to a two-body problem. The contribution of the 1s1/2 orbital to the ground state configuration in 11Be, characterized by the spectroscopic factor, S, has been extracted from direct reaction data by many groups over the past five decades with discrepant results. An experiment was performed at the Holifield Radioactive Ion Beam Facility using a 10Be primary beam at four different energies with the goal of resolving the discrepancy through a consistent analysis of elastic, inelastic, and transfer channels. Faddeev-type calculations, released after the publication of the experimental results, show that dynamic core excitation in the transfer process can lead to reduced differential cross sections at higher beam energies. This reduction would lead to the extraction of decreasing values of S with increasing beam energy. A 10Be(d,p) measurement at Ed greater than 25 MeV is necessary to investigate the effects of core excitation in the reaction.

  14. Tilting of carbon encapsulated metallic nanocolumns in carbon-nickel nanocomposite films by ion beam assisted deposition

    Energy Technology Data Exchange (ETDEWEB)

    Krause, Matthias [Helmholtz-Zentrum Dresden-Rossendorf, PF-510119, 01314 Dresden (Germany); Technische Universitaet Dresden, D-01062 Dresden (Germany); Muecklich, Arndt; Zschornak, Matthias; Wintz, Sebastian; Gemming, Sibylle; Abrasonis, Gintautas [Helmholtz-Zentrum Dresden-Rossendorf, PF-510119, 01314 Dresden (Germany); Oates, Thomas W. H. [Leibniz-Institut fuer Analytische Wissenschaft, ISAS e.V., Albert-Einstein-Str. 9, 12489 Berlin (Germany); Luis Endrino, Jose [Surfaces and Coatings Department, Instituto de Ciencia de Materiales de Madrid, c/Sor Juana Ines de la Cruz 3, Cantoblanco, 28049 Madrid (Spain); Baehtz, Carsten; Shalimov, Artem [Helmholtz-Zentrum Dresden-Rossendorf, PF-510119, 01314 Dresden (Germany); Rossendorf Beamline, European Synchrotron Radiation Facility, F-38043 Grenoble (France)

    2012-07-30

    The influence of assisting low-energy ({approx}50-100 eV) ion irradiation effects on the morphology of C:Ni ({approx}15 at. %) nanocomposite films during ion beam assisted deposition (IBAD) is investigated. It is shown that IBAD promotes the columnar growth of carbon encapsulated metallic nanoparticles. The momentum transfer from assisting ions results in tilting of the columns in relation to the growing film surface. Complex secondary structures are obtained, in which a significant part of the columns grows under local epitaxy via the junction of sequentially deposited thin film fractions. The influence of such anisotropic film morphology on the optical properties is highlighted.

  15. Reinforced concrete beams strengthened with carbon fiber reinforced polymer by friction hybrid bond technique: Experimental investigation

    International Nuclear Information System (INIS)

    Highlights: • Friction Hybrid Bonded FRP Technique is conducted to strengthen RC beams. • Six specimens with different reinforced methods were tested. • The strengthened effects of different strengthening methods were discussed. • The results obtained from the FEA and experiments are agreed very well. - Abstract: Carbon fiber reinforced polymer (CFRP) can be used to strengthen the reinforced concrete (RC) beams. But premature debonding is the main failure model in ordinary bond technique, and the strengthening effect is limited. In order to improve bonding and restricting sliding displacement, Friction Hybrid Bonded FRP Technique (FHB-FRP) is developed. Six simple-span RC specimen beams with different strengthened methods were tested in four-point bending. The experiment results indicate that FRP debonding can be effectively prevented by the FHB-FRP strengthened beam. The ultimate load-carrying capacity of the specimen strengthened by FHB-FRP technique is able to increase by a factor of 2.13 times compared with the beam strengthened with ordinary bond technique (U-jacketing technique). In addition, the cracking and yielding loads are improved more significantly by FHB-FRP technique than U-jacketing technique. Specimens strengthened with FHB-FRP technique have cracks with a more limited distribution and width. Finally, the finite element method (FEM) is conducted to simulate the behavior of the test specimens. The results obtained from the finite element method are compared with experiment. Excellent agreements have been achieved in the comparison of results

  16. Irradiation of an IBL stave in a 10MeV beta beam

    CERN Document Server

    Bilbao de Mendizabal, J; The ATLAS collaboration; Nuiry, FX; Seez, W

    2013-01-01

    The new IBL detector (Insertable B-Layer), due to be integrated into the ATLAS detector as the closest Pixel layer to the beam pipe during the first LHC long-shutdown (2013), is composed of fourteen stave sub-assemblies. These staves have a triangular cross section carbon foam core, sandwiched between a triangular carbon fibre plate (omega) and a flat top plate (faceplate) onto which the silicon detector modules and services are glued. The assembly is strongly dependant on glue and thermal grease interfaces; high density amorphous materials prone to degradation under high radiation doses. In order to evaluate the mechanical stability and integrity of one of these staves it was decided to impose a very high radiation dose upon it, representative of the full dose IBL will receive in its life-cycle. Because of the lack of availability of proton beams - the closest approximation to the radiation received in operation - with a large enough sweep area and dose it was decided to undertake the experiment using an ind...

  17. Attenuation of 10 MeV electron beam energy to achieve low doses does not affect Salmonella spp. inactivation kinetics

    Science.gov (United States)

    Hieke, Anne-Sophie Charlotte; Pillai, Suresh D.

    2015-05-01

    The effect of attenuating the energy of a 10 MeV electron beam on Salmonella inactivation kinetics was investigated. No statistically significant differences were observed between the D10 values of either Salmonella 4,[5],12:i:- or a Salmonella cocktail (S. 4,[5],12:i:-, Salmonella Heidelberg, Salmonella Newport, Salmonella Typhimurium, Salmonella) when irradiated with either a non-attenuated 10 MeV eBeam or an attenuated 10 MeV eBeam (~2.9±0.22 MeV). The results show that attenuating the energy of a 10 MeV eBeam to achieve low doses does not affect the inactivation kinetics of Salmonella spp. when compared to direct 10 MeV eBeam irradiation.

  18. Measurement of characteristic prompt gamma rays emitted from oxygen and carbon in tissue-equivalent samples during proton beam irradiation

    OpenAIRE

    Polf, Jerimy C.; Panthi, Rajesh; Mackin, Dennis S; McCleskey, Matt; Saastamoinen, Antti; Roeder, Brian T; Beddar, Sam

    2013-01-01

    The purpose of this work was to characterize how prompt gamma (PG) emission from tissue changes as a function of carbon and oxygen concentration, and to assess the feasibility of determining elemental concentration in tissues irradiated with proton beams. For this study, four tissue-equivalent water-sucrose samples with differing densities and concentrations of carbon, hydrogen, and oxygen were irradiated with a 48 MeV proton pencil beam. The PG spectrum emitted from each sample was measured ...

  19. Finite Element Modeling and Free Vibration Analysis of Functionally Graded Nanocomposite Beams Reinforced by Randomly Oriented Carbon Nanotubes

    Directory of Open Access Journals (Sweden)

    Benedict Thomas

    2013-12-01

    Full Text Available This article deals with the finite element modeling and free vibration analysis of functionally graded nanocomposite beams reinforced by randomly oriented straight single-walled carbon nanotubes (SWCNTs. Nanostructural materials can be used to alter mechanical, thermal and electrical properties of polymer-based composite materials, because of their superior properties and perfect atom arrangement. Timoshenko beam theory is used to evaluate dynamic characteristics of the beam. The Eshelby–Mori–Tanaka approach based on an equivalent fiber is used to investigate the material properties of the beam. The equations of motion are derived by using Hamilton’s principle. The finite element method is employed to discretize the model and obtain a numerical approximation of the motion equation. Different SWCNTs distributions in the thickness direction are introduced to improve fundamental natural frequency and dynamic behavior of uniform functionally graded nanocomposite beam. Results are presented in tabular and graphical forms to show the effects of various material distributions, carbon nanotube orientations, shear deformation, slenderness ratios and boundary conditions on the dynamic behavior of the beam. The first five normalized mode shapes for functionally graded carbon nanotube reinforced composite (FG-CNTRC beams with different boundary conditions and different carbon nanotubes (CNTs orientation are presented. The results show that the above mentioned effects play very important role on the dynamic behavior of the beam.

  20. 40 CFR 458.10 - Applicability; description of the carbon black furnace process subcategory.

    Science.gov (United States)

    2010-07-01

    ... carbon black furnace process subcategory. 458.10 Section 458.10 Protection of Environment ENVIRONMENTAL... CATEGORY Carbon Black Furnace Process Subcategory § 458.10 Applicability; description of the carbon black furnace process subcategory. The provisions of this subpart are applicable to discharges resulting...

  1. Localized surface grafting reactions on carbon nanofibers induced by gamma and e-beam irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Evora, M.C., E-mail: cecilia@ieav.cta.br [Institute for Advanced Studies-IEAV/DCTA, Av. Cel Jose Alberto Albano do Amarante, 1-Putim, 12228-001 São Jose dos Campos, SP (Brazil); Araujo, J.R., E-mail: jraraujo@inmetro.gov.br [Instituto Nacional de Metrologia, Qualidade e Tecnologia, Av. Nossa Sra. das Graças, 50, 25250-020 Duque de Caxias, RJ (Brazil); Ferreira, E.H.M. [Instituto Nacional de Metrologia, Qualidade e Tecnologia, Av. Nossa Sra. das Graças, 50, 25250-020 Duque de Caxias, RJ (Brazil); Strohmeier, B.R. [Thermo Fisher Scientific, 5225 Verona Road, Madison, WI 53711 (United States); Silva, L.G.A., E-mail: lgasilva@ipen.br [Institute for Nuclear and Energy Research- IPEN, Av. Prof lineu Prestes, 2242- Cidade Universitaria, 05508-000 SP (Brazil); Achete, C.A. [Instituto Nacional de Metrologia, Qualidade e Tecnologia, Av. Nossa Sra. das Graças, 50, 25250-020 Duque de Caxias, RJ (Brazil)

    2015-04-30

    Graphical abstract: - Highlights: • Methodology for the functionalization of carbon nanofibers was investigated. • Two radiation sources were used to promote grafting reactions: gamma and electron beam. • We report the optimum inhibitor concentration to achieve the functionalization. • Surface of carbon nanofibers showed an increase of oxygen content after irradiation. • The radiation-induced graphitization did not damage the overall sp{sup 2} structure. - Abstract: Electron beam and gamma-ray irradiation have potential application to modify the carbon fiber nanostructures in order to produce useful defects in the graphitic structure and create reactive sites. In this study, the methodology to functionalize carbon nanofiber (CNF), via a radiation process and using acrylic acid as a source of oxygen functional groups, was investigated. The samples were submitted to a direct grafting radiation process with electron beam and gamma-ray source. Several parameters were changed such as: acrylic acid concentration, radiation dose and percentage of inhibitor necessary to achieve functionalization, with higher percentage of oxygen functional groups on CNF surface, and better dispersion. The better results achieved were when mixing CNF in a solution of acrylic acid with 6% of inhibitor (FeSO{sub 4}·7H{sub 2}O) and irradiated at 100 kGy. The samples were characterized by X-ray photoelectron spectroscopy and the surface composition (atomic%) showed a significant increase of oxygen content for the samples after irradiation. Also, the dispersion of the functionalized CNF in water was stable during months which may be a good indication that the functionalization process of CNF via ionizing radiation was successful.

  2. Reactions with a 10Be beam to study the one-neutron halo nucleus 11Be

    CERN Document Server

    Jones, K L

    2016-01-01

    Halo nuclei are excellent examples of few-body systems consisting of a core and weakly-bound halo nucleons. Where there is only one nucleon in the halo, as in 11Be, the many-body problem can be reduced to a two-body problem. The contribution of the 1s1/2 orbital to the ground state configuration in 11Be, characterized by the spectroscopic factor, S, has been extracted from direct reaction data by many groups over the past five decades with discrepant results. An experiment was performed at the Holifield Radioactive Ion Beam Facility using a 10Be primary beam at four different energies with the goal of resolving the discrepancy through a consistent analysis of elastic, inelastic, and transfer channels. Faddeev-type calculations, released after the publication of the experimental results, show that dynamic core excitation in the transfer process can lead to reduced differential cross sections at higher beam energies. This reduction would lead to the extraction of decreasing values of S with increasing beam ener...

  3. Surface dose variations in 6 and 10 MV flattened and flattening filter-free (FFF) photon beams.

    Science.gov (United States)

    Cashmore, Jason

    2016-01-01

    As the use of linear accelerators operating in flattening filter-free (FFF) modes becomes more widespread, it is important to have an understanding of the surface doses delivered to patients with these beams. Flattening filter removal alters the beam quality and relative contributions of low-energy X-rays and contamination electrons in the beam. Having dosimetric data to describe the surface dose and buildup regions under a range of conditions for FFF beams is important if clinical decisions are to be made. An Elekta Synergy linac with standard MLCi head has been commissioned to run at 6 MV and 10 MV running with the flattening filter in or out. In this linac the 6 MV FFF beam has been energy-matched to the clinical beam on the central axis (D10). The 10 MV beam energy has not been adjusted. The flattening filter in both cases is replaced by a thin (2 mm) stainless steel plate. A thin window parallel plate chamber has been used to measure a comprehensive set of surface dose data in these beams for variations in field size and SSD, and for the presence of attenuators (wedge, shadow tray, and treatment couch). Surface doses are generally higher in FFF beams for small field sizes and lower for large field sizes with a crossover at 10 × 10 cm2 at 6 MV and 25 × 25 cm2 at 10 MV. This trend is also seen in the presence of the wedge, shadow tray, and treatment couch. Only small differences (SSD. At both 6 and 10 MV the filter-free beams show far less variation with field size than conventional beams. By removing the flattening filter, a source of contamination electrons is exchanged for a source of low-energy photons (as these are no longer attenuated). In practice these two components almost balance out. No significant effects on surface dose are expected by the introduction of FFF delivery. PMID:27685127

  4. Charged particle's flux measurement from PMMA irradiated by 80 MeV/u carbon ion beam

    CERN Document Server

    Agodi, C; Bellini, F; Cirrone, G A P; Collamati, F; Cuttone, G; De Lucia, E; De Napoli, M; Di Domenico, A; Faccini, R; Ferroni, F; Fiore, S; Gauzzi, P; Iarocci, E; Marafini, M; Mattei, I; Muraro, S; Paoloni, A; Patera, V; Piersanti, L; Romano, F; Sarti, A; Sciubba, A; Vitale, E; Voena, C

    2012-01-01

    Hadrontherapy is an emerging technique in cancer therapy that uses beams of charged particles. To meet the improved capability of hadrontherapy in matching the dose release with the cancer position, new dose monitoring techniques need to be developed and introduced into clinical use. The measurement of the fluxes of the secondary particles produced by the hadron beam is of fundamental importance in the design of any dose monitoring device and is eagerly needed to tune Monte Carlo simulations. We report the measurements done with charged secondary particles produced from the interaction of a 80 MeV/u fully stripped carbon ion beam at the INFN Laboratori Nazionali del Sud, Catania, with a Poly-methyl methacrylate target. Charged secondary particles, produced at 90$\\degree$ with respect to the beam axis, have been tracked with a drift chamber, while their energy and time of flight has been measured by means of a LYSO scintillator. Secondary protons have been identified exploiting the energy and time of flight in...

  5. Evaluation of plastic materials for range shifting, range compensation, and solid-phantom dosimetry for carbon-ion beams

    CERN Document Server

    Kanematsu, Nobuyuki; Ogata, Risa

    2012-01-01

    Purpose: Beam range control is the essence of radiotherapy with heavy charged particles. In conventional broad-beam delivery, fine range adjustment is achieved by insertion of range shifting and compensating materials. Ideally, such material should be water equivalent as well as that for dosimetry. In this study, we evaluated dosimetric water equivalency of four common plastics, HDPE, PMMA, PET, and POM, by uniformity of effective densities for carbon-ion-beam interactions. Methods: Using the Bethe formula for stopping, the Gottschalk formula for multiple scattering, and the Sihver formula for nuclear interactions, we calculated the effective densities of the plastics for these interactions. We tested HDPE, PMMA, and POM in carbon-ion-beam experiment and measured attenuations of carbon ions, which were compared with empirical linear-attenuation-model calculations. Results: The theoretical calculations resulted in reduced multiple scattering and increased nuclear interactions for HDPE compared to water, which ...

  6. 10 MeV Electron Beam Test Using Gas Electron Multiplier (GEM) Detectors

    Science.gov (United States)

    Hahn, C. H.; Kim, I. G.; Park, S. T.; Kim, W. J.; Yoo, D. S.; Moon, B. S.; Ha, S. Y.; Ahn, B. J.; Ha, Y. J.; Jung, C. Y.; Jung, S. H.; Cho, B. H.; Lee, B. C.; Han, Y. H.; Chung, C. E.; Li, J.; White, A. P.; Yu, J.

    2006-10-01

    10 MeV electron beam has been tested using a single channel double gas electron multiplier (GEM) detector constructed by Changwon National University and a multi-channel double GEM chamber by the University of Texas at Arlington. It has been demonstrated that both detectors are able to detect signals generated by high energy electrons as well as x-rays. By analyzing the chamber output signals captured by oscilloscope, it is believed that the x-ray was produced by bremsstrahlung while electrons were decelerating in a 2 mm lead plate. The time profile of the KAERI's 10 MeV electron beam bunches was determined based on the calculated angular distribution of electrons by multiple scattering in the lead plate. Furthermore, the spatial electron density distribution has been extrapolated by using the time profile. The effective gain of the GEM chamber has been estimated by analyzing the measured output currents of the chamber. It is important that the time and spatial profiles of the high energy electron beam could be determined using GEM detectors, which suggests that GEM might have an application as a calorimeter for a large scale accelerator. Details of experimental procedure will be discussed.

  7. Non-invasive monitoring of therapeutic carbon ion beams in a homogeneous phantom by tracking of secondary ions.

    Science.gov (United States)

    Gwosch, K; Hartmann, B; Jakubek, J; Granja, C; Soukup, P; Jäkel, O; Martišíková, M

    2013-06-01

    Radiotherapy with narrow scanned carbon ion beams enables a highly accurate treatment of tumours while sparing the surrounding healthy tissue. Changes in the patient's geometry can alter the actual ion range in tissue and result in unfavourable changes in the dose distribution. Consequently, it is desired to verify the actual beam delivery within the patient. Real-time and non-invasive measurement methods are preferable. Currently, the only technically feasible method to monitor the delivered dose distribution within the patient is based on tissue activation measurements by means of positron emission tomography (PET). An alternative monitoring method based on tracking of prompt secondary ions leaving a patient irradiated with carbon ion beams has been previously suggested. It is expected to help in overcoming the limitations of the PET-based technique like physiological washout of the beam induced activity, low signal and to allow for real-time measurements. In this paper, measurements of secondary charged particle tracks around a head-sized homogeneous PMMA phantom irradiated with pencil-like carbon ion beams are presented. The investigated energies and beam widths are within the therapeutically used range. The aim of the study is to deduce properties of the primary beam from the distribution of the secondary charged particles. Experiments were performed at the Heidelberg Ion Beam Therapy Center, Germany. The directions of secondary charged particles emerging from the PMMA phantom were measured using an arrangement of two parallel pixelated silicon detectors (Timepix). The distribution of the registered particle tracks was analysed to deduce its dependence on clinically important beam parameters: beam range, width and position. Distinct dependencies of the secondary particle tracks on the properties of the primary carbon ion beam were observed. In the particular experimental set-up used, beam range differences of 1.3 mm were detectable. In addition, variations in

  8. Laser transformation hardening on rod-shaped carbon steel byGaussian beam

    Institute of Scientific and Technical Information of China (English)

    Jong-Do KIM; Myeong-Hoon LEE; Su-Jin LEE; Woon-Ju KANG

    2009-01-01

    Laser transformation hardening(LTH) is one of the laser surface modification processes. The surface hardening of rod-shaped carbon steel (SM45C) was performed by lathe-based laser composite processor with Gaussian-beam optical head. The LTH characteristics by dominant processes, longitudinal and depth directional hardness distributions and behaviors of phase transformation in hardened zones were examined. Especially, two concepts of circumferential speed and theoretical overlap rate were applied. When laser power increased or circumferential speed decreased, the surface hardening depth gradually increases due to the increased heat input. Moreover, the longitudinal hardness distribution particularly shows periodicity of repetitive increase and decrease, which results from tempering effect by overlap. Finally, the feasibility of laser transformation hardening is verified by using the beam with Gaussian intensity distribution.

  9. Surface dose variations in 6 and 10 MV flattened and flattening filter-free (FFF) photon beams.

    Science.gov (United States)

    Cashmore, Jason

    2016-01-01

    As the use of linear accelerators operating in flattening filter-free (FFF) modes becomes more widespread, it is important to have an understanding of the surface doses delivered to patients with these beams. Flattening filter removal alters the beam quality and relative contributions of low-energy X-rays and contamination electrons in the beam. Having dosimetric data to describe the surface dose and buildup regions under a range of conditions for FFF beams is important if clinical decisions are to be made. An Elekta Synergy linac with standard MLCi head has been commissioned to run at 6 MV and 10 MV running with the flattening filter in or out. In this linac the 6 MV FFF beam has been energy-matched to the clinical beam on the central axis (D10). The 10 MV beam energy has not been adjusted. The flattening filter in both cases is replaced by a thin (2 mm) stainless steel plate. A thin window parallel plate chamber has been used to measure a comprehensive set of surface dose data in these beams for variations in field size and SSD, and for the presence of attenuators (wedge, shadow tray, and treatment couch). Surface doses are generally higher in FFF beams for small field sizes and lower for large field sizes with a crossover at 10 × 10 cm2 at 6 MV and 25 × 25 cm2 at 10 MV. This trend is also seen in the presence of the wedge, shadow tray, and treatment couch. Only small differences (free beams show far less variation with field size than conventional beams. By removing the flattening filter, a source of contamination electrons is exchanged for a source of low-energy photons (as these are no longer attenuated). In practice these two components almost balance out. No significant effects on surface dose are expected by the introduction of FFF delivery.

  10. Carbon doping of GaN with CBr4 in radio-frequency plasma-assisted molecular beam epitaxy

    OpenAIRE

    Green, D S; Mishra, U. K.; Speck, J.S.

    2004-01-01

    Carbon tetrabromide (CBr4) was studied as an intentional dopant during rf plasma molecular beam epitaxy of GaN. Secondary ion mass spectroscopy was used to quantify incorporation behavior. Carbon was found to readily incorporate under Ga-rich and N-rich growth conditions with no detectable bromine incorporation. The carbon incorporation [C] was found to be linearly related to the incident CBr4 flux. Reflection high-energy electron diffraction, atomic force microscopy and x-ray diffraction wer...

  11. Relative biological effects of carbon ion beams on mouse intestinal crypts

    Energy Technology Data Exchange (ETDEWEB)

    Basaki, Kiyoshi; Abe, Yoshinao [Hirosaki Univ., Aomori (Japan). School of Medicine; Tatsuzaki, Hideo; Akaizawa, Takashi; Ando, Soichiro; Ando, Koichi

    1998-03-01

    The relative biological effect (RBE) of carbon ion beams on mouse intestinal crypt cells were studied. Survival fractions of apoptotic sensitive cells, mitotic delay and colony assay were used for endpoints. Female C3H mice were total body irradiated using a carbon ion beam (290 MeV/u, 6 cm SOBP) at the National Institute of Radiological Science. For counting apoptosis and mitosis, the animals were irradiated either at LET of 70 keV/mm or 40 keV/mm. Fifteen minutes after irradiation, the mice received vincristine sulfate (0.8 mg/kg) and were sacrificed 2 hours and 45 minutes later. For colony assay, the animals were irradiated at an LET of 70 keV/mm and were sacrificed 3.5 days later. Jejunum were excised, fixed and cut into slices. The slides were stained with Hematoxylin and Eosin. Apoptosis-pyknotic cell- and mitosis were counted and survival fractions of apoptotic sensitive cells and mitotic delay time were obtained. The number of colonies were counted and survival fractions per circumference were obtained. Using these endpoints, RBEs were obtained. For survival fractions of apoptotic sensitive cells, no LET difference was observed and RBE was 1.7. For mitotic delay time, RBE was 2.3 and 1.7 at an LET of 70 keV/mm and 40 keV/mm, respectively. For colony assay, the RBE was 2.0-2.1. The different RBEs from three endpoints of the jejunal crypt may reflect each nature of the radiosensitivity to the carbon ion beam. In summary that mitotic delay time exhibited the same RBE as colony assay and RBE regarding apoptosis was less than those RBEs. (author)

  12. Fractional frequency instability in the 10{sup -14} range with a thermal beam optical frequency reference

    Energy Technology Data Exchange (ETDEWEB)

    McFerran, John J.; Luiten, Andre N. [School of Physics, University of Western Australia, 35 Stirling Highway, Crawley 6009, W.A. (Australia)

    2010-02-15

    We demonstrate a means of increasing the signal-to-noise ratio in a Ramsey-Borde interferometer with spatially separated oscillatory fields on a thermal atomic beam. The {sup 1}S{sub 0}{r_reversible}{sup 3}P{sub 1} intercombination line in neutral {sup 40}Ca is used as a frequency discriminator, with an extended cavity diode laser at 423 nm probing the ground state population after a Ramsey-Borde sequence of 657 nm light-field interactions with the atoms. Evaluation of the instability of the Ca frequency reference is carried out by comparison with (i) a hydrogen-maser and (ii) a cryogenic sapphire oscillator. In the latter case the Ca reference exhibits a square-root {Lambda} variance of 9.2x10{sup -14} at 1 s and 2.0x10{sup -14} at 64 s. This is an order-of-magnitude improvement for optical beam frequency references, to our knowledge. The shot noise of the readout fluorescence produces a limiting square-root {Lambda} variance of 7x10{sup -14}/{radical}({tau}), highlighting the potential for improvement. This work demonstrates the feasibility of a portable frequency reference in the optical domain with 10{sup -14} range frequency instability.

  13. Experimental study on fire protection methods of reinforced concrete beams strengthened with carbon fiber reinforced polymer

    Institute of Scientific and Technical Information of China (English)

    HU Kexu; HE Guisheng; LU Fan

    2007-01-01

    In this paper,two reinforced concrete (RC) beams strengthened with carbon fiber reinforced polymer (CFRP)and attached with thick-painted fire resistant coating were tested for fire resistance following the standard fire testing procedures.The experimental results show that the specimen pasted with the insulated layer of 50 mm in thickness could resist fire for 2.5 h.It is also demonstrated that the steel wire mesh embedded in the insulated layer can effectively prevent it from cracking and eroding under firing.

  14. Measurement of neutral current coherent neutral pion production on carbon in a few-GeV neutrino beam

    CERN Document Server

    Kurimoto, Y; Brice, S J; Bugel, L; Catala-Perez, J; Cheng, G; Conrad, J M; Djurcic, Z; Dore, U; Finley, D A; Franke, A J; Giganti, C; Gomez-Cadenas, J J; Guzowski, P; Hanson, A; Hayato, Y; Hiraide, K; Jover-Manas, G; Karagiorgi, G; Katori, T; Kobayashi, Y K; Kobilarcik, T; Kubo, H; Louis, W C; Loverre, P F; Ludovici, L; Mahn, K B M; Mariani, C; Masuike, S; Matsuoka, K; McGary, V T; Metcalf, W; Mills, G B; Mitsuka, G; Miyachi, Y; Mizugashira, S; Moore, C D; Nakajima, Y; Nakaya, T; Napora, R; Nienaber, P; Orme, D; Otani, M; Russell, A D; Sanchez, F; Shaevitz, M H; Shibata, T -A; Sorel, M; Stefanski, R J; Takei, H; Tanaka, H -K; Tanaka, M; Tayloe, R; Taylor, I J; Tesarek, R J; Uchida, Y; Van de Water, R; Walding, J J; Wascko, M O; White, H B; Wilking, M J; Yokoyama, M; Zeller, G P; Zimmerman, E D

    2010-01-01

    The SciBooNE Collaboration reports a measurement of neutral current coherent neutral pion production on carbon by a muon neutrino beam with average energy 0.8 GeV. The separation of coherent from inclusive neutral pion production has been improved by detecting recoil protons from resonant neutral pion production. We measure the ratio of the neutral current coherent neutral pion production to total charged current cross sections to be (1.16 +/- 0.24) x 10-2. The ratio of charged current coherent pion to neutral current coherent pion production is calculated to be 0.14+0.30 -0.28, using our published charged current coherent pion measurement.

  15. Two Types of Mass Abundance Distributions for Anionic Carbon Clusters Investigated by Laser Vaporization and Pulsed Molecular Beam Techniques

    Institute of Scientific and Technical Information of China (English)

    ZHAI Hua-Jin; LIU Bing-Chen; NI Guo-Quan; XUZhi-Zhan

    2000-01-01

    Two types of mass spectra for anionic carbon clusters Cn- have been revealed using laser vaporization and pulsed molecular beam techniques. The less structured mass spectrum characteristic of the magic-numbers at n = 5, 8,11, 15, and 17 is established at the early stage of the cluster formation process, namely, in the laser vaporization process. The more structured one is featured for a regular odd-even alternation and the magic numbers at n =10, 12, 16, 18, 22, and 28, and has been developed only after extensive clustering and qnenching processes, where low-energy electron attachment plays a vital role. Transition between these two types of mass spectra can be realized by controlling either the strength of the pulsed gas flow or the synchronism between the gas flow and the laser vaporization.

  16. Study on Regeneration of Powdered Activated Carbon by Electron Beam%电子束再生粉状活性炭的研究

    Institute of Scientific and Technical Information of China (English)

    吴明红; 包伯荣; 陈捷; 陆丽蓉

    2001-01-01

    The powdered activated carbon which had adsorbed phenylglycine solution from pharmaceutics factory can be regenerated by mean of irradiation of high-energy electron beams in oxygen, nitrogen and water vapor respectively. The effects of radiation dose and beam current on regeneration of activated carbon in different atmosphere were studied. Differential scanning calorimetry (DSC) and the iodine number of activated carbon were used to monitor the change of carbon adsorption. The results show that the powder activated carbon polluted with phenlglycine could be regenerated effectively by irradiation of high energy electron beams in nitrogen stream. The generation did not need high temperature, and the weight loss of carbon and energy consumption were minimum.

  17. 电子束再生粉状活性炭的研究%Study on Regeneration of Powdered Activated Carbon by Electron Beam

    Institute of Scientific and Technical Information of China (English)

    吴明红; 包伯荣; 陈捷; 陆丽蓉

    2000-01-01

    The powdered activated carbon which had adsorbed phenylglycine solution from pharmaceutics factory can be regenerated by mean of irradiation of high-energy electron beams in oxygen, nitrogen and water vapor respectively. The effects of radiation dose and beam current on regeneration of activated carbon in different atmosphere were studied. Differential scanning calorimetry (DSC) and the iodine number of activated carbon were used to monitor the change of carbon adsorption. The results show that the powder activated carbon polluted with phenlglycine could be regenerated effectively by irradiation of high energy electron beams in nitrogen stream. The generation did not need high temperature, and the weight loss of carbon and energy consumption were minimum.

  18. Treatment of industrial effluents using electron beam accelerator and adsorption with activated carbon. A comparative study

    International Nuclear Information System (INIS)

    Several methods are used In the pollutant removal from Industrial and domestic wastewater. However when the degradation of toxic organic pollutants, mainly the recalcitrant is objectified, the conventional treatments usually do not meet the desirable performance in the elimination or decrease the impact when the effluent are released to the environment what takes to the research of alternative methods that seek the improvement of the efficiency of the wastewater treatment systems jointly employees or separately. This work presents a study of degradation/removal of pollutants organic compounds comparing two methods using radiation from industrial electron beam and granular activated carbon (GAC). The removal efficiency of the pollutants was evaluated and it was verified that the efficiency of adsorption with activated carbon is similar to the radiation method. The obtained results allowed to evaluated the relative costs of these methods. (author)

  19. Transplantation of ES cells to Parkinson model rat irradiated with carbon ion beam

    International Nuclear Information System (INIS)

    The present study was designed to make a new Parkinson disease model using carbon ion beam. We irradiated right medial forebrain bundle of adult SD rats with charged carbon particles (290 MeV/nucleon, Mono peak, 150 Gy) and damaged right dopaminergic neurons pathway. To irradiate precisely, rats were set in the stereotactic frame with ear bars. Four weeks after the irradiation, behavioral test and in vitro autoradiography showed hemi-Parkinson model as well as 6-OHDA lesioned rats. Pathological examinations showed cell death, gliosis and inflammations at the irradiated area. However, no obvious alteration was observed at the surrounding normal tissue. These results indicated utility and validity of this method. (author)

  20. Neutron contamination of Varian Clinac iX 10 MV photon beam using Monte Carlo simulation

    Science.gov (United States)

    Yani, S.; Tursinah, R.; Rhani, M. F.; Soh, R. C. X.; Haryanto, F.; Arif, I.

    2016-03-01

    High energy medical accelerators are commonly used in radiotherapy to increase the effectiveness of treatments. As we know neutrons can be emitted from a medical accelerator if there is an incident of X-ray that hits any of its materials. This issue becomes a point of view of many researchers. The neutron contamination has caused many problems such as image resolution and radiation protection for patients and radio oncologists. This study concerns the simulation of neutron contamination emitted from Varian Clinac iX 10 MV using Monte Carlo code system. As neutron production process is very complex, Monte Carlo simulation with MCNPX code system was carried out to study this contamination. The design of this medical accelerator was modelled based on the actual materials and geometry. The maximum energy of photons and neutron in the scoring plane was 10.5 and 2.239 MeV, respectively. The number and energy of the particles produced depend on the depth and distance from beam axis. From these results, it is pointed out that the neutron produced by linac 10 MV photon beam in a typical treatment is not negligible.

  1. The CBS-The Most Cost Effective and High Performance Carbon Beam Source Dedicated for a New Generation Cancer Therapy

    CERN Document Server

    Kumada, Masayuki; Leivichev, E B; Parkhomchuk, Vasily; Podgorny, Fedor; Rastigeev, Sergey; Reva, Vladimir B; Skrinsky, Aleksander Nikolayevich; Vostrikov, Vladimir

    2005-01-01

    A Carbon ion beam is a superior tool to x-rays or a proton beam in both physical and biological doses in treating a cancer. A Carbon beam has an advantage in treating radiation resistant and deep-seated tumors. Its radiological effect is of a mitotic independent nature. These features improve hypofractionation, typically reducing the number of irradiations per patient from 35 to a few. It has been shown that a superior QOL(Quality Of Life) therapy is possible by a carbon beam.The only drawback is its high cost. Nevertheless, tens of Prefectures and organizations are eagerly considering the possibility of having a carbon ion therapy facility in Japan. Germany, Austria, Italy, China, Taiwan and Korea also desire to have one.A carbon beam accelerator of moderate cost is about 100 Million USD. With the "CBS" design philosophy, which will be described in this paper, the cost could be factor of 2 or 3 less, while improving its performance more than standard designs. Novel extraction techniques, a new approach to a ...

  2. Study of the RP-10 reactor neutron beam applied to the neutron radiography

    International Nuclear Information System (INIS)

    We have studied the RP-10 reactor radial neutron beam No. 3, which is used for neutron radiographies, by comparing radiograph's with and without the inner duct, and neutron flux determination with in flakes along the external duct, being the presence of photons creating signals at comparable levels of neutron effects, which reduce the quality of the analysis, values around 106 and 104 n/cm2s for thermal and epithermal flux were obtained respectively. It is recommended evaluate the design of the internal duct which presents strong photon emission. (authors).

  3. Localized surface grafting reactions on carbon nanofibers induced by gamma and e-beam irradiation

    Science.gov (United States)

    Evora, M. C.; Araujo, J. R.; Ferreira, E. H. M.; Strohmeier, B. R.; Silva, L. G. A.; Achete, C. A.

    2015-04-01

    Electron beam and gamma-ray irradiation have potential application to modify the carbon fiber nanostructures in order to produce useful defects in the graphitic structure and create reactive sites. In this study, the methodology to functionalize carbon nanofiber (CNF), via a radiation process and using acrylic acid as a source of oxygen functional groups, was investigated. The samples were submitted to a direct grafting radiation process with electron beam and gamma-ray source. Several parameters were changed such as: acrylic acid concentration, radiation dose and percentage of inhibitor necessary to achieve functionalization, with higher percentage of oxygen functional groups on CNF surface, and better dispersion. The better results achieved were when mixing CNF in a solution of acrylic acid with 6% of inhibitor (FeSO4·7H2O) and irradiated at 100 kGy. The samples were characterized by X-ray photoelectron spectroscopy and the surface composition (atomic%) showed a significant increase of oxygen content for the samples after irradiation. Also, the dispersion of the functionalized CNF in water was stable during months which may be a good indication that the functionalization process of CNF via ionizing radiation was successful.

  4. Effects of carbon ion beam irradiation on the shoot regeneration from in vitro axillary bud explants of the Impatiens hawkeri

    Science.gov (United States)

    Zhou, Libin; Zhou, Libin; Li, Wenjian; Li, Ping; Dong, Xicun; Qu, Ying; Ma, Shuang; Li, Qiang

    Accelerated ion beams is an excellent mutagen in plant breeding which can induce higher mutation frequencies and wider mutation spectrum than those of low linear energy transfer (LET) irradiations, such as X-rays (Okamura et al. 2003, Yamaguchi et al. 2003). Mutation breeding operation of two Saintpaulia ionahta cultivars using the method combining plant tissue culture technique and carbon ion beam irradiations were set out at Institute of Modern Physics from 2005 (Zhou et al. 2006). The effects of 960 MeV carbon ion beam and 8 MeV X-ray irradiations on regenerated shoots of Impatiens hawkeri from another kind of explants named in vitro axillary buds explants were studied recently. The biology endpoints in this study included relative number of roots (RNR), relative length of roots (RLR), relative height of shoots (RHS), relative number of nodes (RNN), survival fraction (SF) and morphology changes in the regenerated shoots. The experimental results showed that carbon ion beams inhibited the root and stem developments of axillary bud explants more severely than X-rays did. And the 50% lethal dose (LD50 ) is about 23.3 Gy for the carbon ion beam and 49.1 Gy for the X-rays, respectively. Relative biological effectiveness (RBE) of Impatiens hawkeri with respect to X-rays according to 50% SF was about two. Secondly, the percentage of shoots regenerated with malformed shoots including curliness, carnification, nicks in all Impatiens hawkeri axillary bud explants irradiated with carbon ion beam at 20 Gy accounted for 55.6%, while the highest number for the 40 Gy X-ray irradiation was 40%. Last, many regenerated shoots whose vascular bundle fused together were obtained only from explants irradiated with carbon ion beams. Based on the results above, it can be concluded that the effect of mutation induction by carbon ion beam irradiation on the axillary explants of Impatiens hawkeri is better than that by X-ray irradiation; and the optimal mutagenic dose varies from 20 Gy

  5. Flexural rigidity evolvement laws of reinforced concrete beams strengthened with carbon fiber laminates

    Institute of Scientific and Technical Information of China (English)

    NIU Peng-zhi; HUANG Pei-yan; DENG Jun; HAN Qiang

    2007-01-01

    Extensive research has shown that externally bonded carbon fiber reinforced polymer (CFRP) laminates are particularly suitable for improving the fatigue behavior of reinforced concrete (RC) beams. This paper presents the research on flexural rigidity evolvement laws by testing 14 simple-supported RC beams strengthened with carbon fiber laminates (CFL) under cyclic load, and 2 under monotone load as a reference. The cyclic load tests revealed the peak load applied onto the surface of a supported RC beam strengthened with CFL is linear to the logarithm of its fatigue life, and the flexural rigidity evolvement undergoes three distinct phases: a rapid decrease from the start to about 5% of the fatigue life; an even development from 5% to about 99% of the fatigue life; and a succedent rapid decrease to failure. When the ratio of fatigue cycles to the fatigue life is within 0.05 to 0.99, the flexural rigidity varies linearly with the ratio. The peak load does not affect the flexural rigidity evolvement if it is not high enough to make the main reinforcements yield. The dependences of the flexural rigidity of specimens formed in the same group upon their fatigue cycles normalized by fatigue life are almost coincident. This implies the flexural rigidity may be a material parameter independent of the stress level. These relationships of flexural rigidity to fatigue cycles, and fatigue life may be able to provide some hints for fatigue design and fatigue life evaluation of RC member strengthened with CFL; nevertheless the findings still need verifying by more experiments.

  6. Charge exchange recombination spectroscopy measurements in the extreme ultraviolet region of central carbon concentrations during high power neutral beam heating in TFTR [Tokamak Fusion Test Reactor

    International Nuclear Information System (INIS)

    The carbon concentration in the central region of TFTR discharges with high power neutral beam heating has been measured by charge-extracted recombination spectroscopy (CXRS) of the C+5 n = 3--4 transition in the extreme ultraviolet region. The carbon concentrations were deduced from absolute measurements of the line brightness using a calculation of the beam attenuation and the appropriate cascade-corrected line excitation rates. As a result of the high ion temperatures in most of the discharges, the contribution of beam halo neutrals to the line brightness was significant and therefore had to be included in the modeling of the data. Carbon concentrations have been measured in discharges with Ip = 1.0-1.6 MA and beam power in the range of 2.6-30 MW, including a number of supershots. The results are in good agreement with carbon concentrations deduced from the visible bremsstrahlung Zeff and metallic impurity concentrations measured by x-ray pulse-height analysis, demonstrating the reliability of the atomic rates used in the beam attenuation and line excitation calculations. Carbon is the dominant impurity species in these discharges; the oxygen concentration measured via CXRS in a high beam power case was 0.0006 of ne, compard to 0.04 for carbon. Trends with Ip and beam power in the carbon concentration and the inferred deuteron concentration are presented. The carbon concentration is independent of Ip and decreases from 0.13 at 2.6 MW beam power to 0.04 at 30 MW, while the deuteron concentration increases from 0.25 to 0.75 over the same range of beam power. These changes are primarily the result of beam particle fueling, as the carbon density did not vary significantly with beam power. The time evolutions of the carbon and deuteron concentrations during two high power beam pulses, one which exhibited a carbon bloom and one which did not, are compared. 30 refs., 12 figs., 2 tabs

  7. Assessment of adhesive setting time in reinforced concrete beams strengthened with carbon fibre reinforced polymer laminates

    International Nuclear Information System (INIS)

    Highlights: ► This study investigated the effect of adhesive setting time on the modal parameters. ► Modal parameters recommend the 18th day as the maturity age of the adhesive. ► Static data recommend 7th day as the maturity age of the adhesive. ► Setting time affects the modal parameters as tool for assessment repaired structures. ► Carrying the modal parameters after 1st day results in 55% loss of the actual improvement. -- Abstract: The strengthened effectiveness and the performance capacity of repaired Reinforced Concrete (RC) structures with Carbon Fibre Reinforced Polymer (CFRP) sheets is dependent on the properties of the adhesive interface layer. Adhesive material requires a specific setting time to achieve the maximum design capacity. Adhesive producer provides technical data which demonstrates the increase with time of the capacity, up to the maximum. The aim of this study is to investigate the effect of the adhesive setting time on the modal parameters as an indication of the effectiveness of CFRP on repaired RC beams. Firstly, datum modal parameters were determined on the undamaged beam and subsequently the parameters were obtained when damaged was induced on the RC beam by application of load until the appearance of the first crack. Finally, the RC beam is repaired with externally bonded CFRP sheets, and modal parameters are once again applied after 0.5, 1, 2, 3, 5, 8, 11, 15 and 18 days. The comparison is made with the data based on half day results in order to monitor the change in the modal parameters corresponding to the adhesive setting time. The modal parameters where used as indicators for the effectiveness of CFRP are affected by the adhesive time as shown in this study. Results are compared with the adhesive technical data provided by the adhesive producer.

  8. Analytic expressions for the inelastic scattering and energy loss of electron and proton beams in carbon nanotubes

    International Nuclear Information System (INIS)

    We have determined ''effective'' Bethe coefficients and the mean excitation energy of stopping theory (I-value) for multiwalled carbon nanotubes (MWCNTs) and single-walled carbon nanotube (SWCNT) bundles based on a sum-rule constrained optical-data model energy loss function with improved asymptotic properties. Noticeable differences between MWCNTs, SWCNT bundles, and the three allotropes of carbon (diamond, graphite, glassy carbon) are found. By means of Bethe's asymptotic approximation, the inelastic scattering cross section, the electronic stopping power, and the average energy transfer to target electrons in a single inelastic collision, are calculated analytically for a broad range of electron and proton beam energies using realistic excitation parameters.

  9. Analytic expressions for the inelastic scattering and energy loss of electron and proton beams in carbon nanotubes

    Science.gov (United States)

    Emfietzoglou, D.; Kyriakou, I.; Garcia-Molina, R.; Abril, I.; Kostarelos, K.

    2010-09-01

    We have determined "effective" Bethe coefficients and the mean excitation energy of stopping theory (I-value) for multiwalled carbon nanotubes (MWCNTs) and single-walled carbon nanotube (SWCNT) bundles based on a sum-rule constrained optical-data model energy loss function with improved asymptotic properties. Noticeable differences between MWCNTs, SWCNT bundles, and the three allotropes of carbon (diamond, graphite, glassy carbon) are found. By means of Bethe's asymptotic approximation, the inelastic scattering cross section, the electronic stopping power, and the average energy transfer to target electrons in a single inelastic collision, are calculated analytically for a broad range of electron and proton beam energies using realistic excitation parameters.

  10. Ion-beam and microwave-stimulated functionalization and derivatization of carbon nanotubes

    Science.gov (United States)

    Makala, Raghuveer S.

    Derivatizing carbon nanotubes (CNTs) with other low-dimensional nanostructures is of widespread interest for creating CNT-based nanocomposites and devices. Conventional routes based on wet-chemical oxidation or hydrophobic adsorption do not allow premeditated control over the location or spatial extent of functionalization. Moreover, aggressive oxidative treatments and agitation in corrosive environments lead to CNT shortening, damage, and incorporation of excess impurity concentrations. Thus, it is imperative to explore and develop alternative functionalization methods to overcome these shortcomings. The work presented in this thesis outlines two such methodologies: one based on focused ion irradiation for siteselective functionalization and the other that employs microwave-stimulation for mild, yet rapid and homogenous CNT functionalization. The utility of 10 and 30 kcV Ga+ focused ion beams (FIB) to thin, slice, weld, and alter the structure and composition at precise locations along the CNT axis is presented. This strategy of harnessing ion-beam-induced defect generation and doping is attractive for modulating chemical and electrical properties along the CNT length, and fabricate CNT-based heterostructures and networks. A novel approach that utilizes focused ion irradiation to site-selectively derivatize preselected segments of CNTs with controlled micro-/nano-scale lateral spatial resolution is demonstrated. Irradiation followed by air-exposure results in functionalized CNT segments ranging from the nanoscopic to the macroscopic scale. The functional moieties are utilized to site-selectively anchor Au nanoparticles, fluorescent nanospheres, an amino acid---lysine, a charge-transfer metalloprotein---azurin, and a photoactive protein---bacteriorhodopsin by means of electrostatic or covalent interactions. This approach is versatile and can be extended to obtaining other molecular moieties and derivatives opening up possibilities for building new types of nano

  11. Measurement of analyzing power for proton-carbon elastic scattering in the coulomb-nuclear interference region with a 22-GeV/c polarized proton beam.

    Science.gov (United States)

    Tojo, J; Alekseev, I; Bai, M; Bassalleck, B; Bunce, G; Deshpande, A; Doskow, J; Eilerts, S; Fields, D E; Goto, Y; Huang, H; Hughes, V; Imai, K; Ishihara, M; Kanavets, V; Kurita, K; Kwiatkowski, K; Lewis, B; Lozowski, W; Makdisi, Y; Meyer, H-O; Morozov, B V; Nakamura, M; Przewoski, B; Rinckel, T; Roser, T; Rusek, A; Saito, N; Smith, B; Svirida, D; Syphers, M; Taketani, A; Thomas, T L; Underwood, D; Wolfe, D; Yamamoto, K; Zhu, L

    2002-07-29

    The analyzing power for proton-carbon elastic scattering in the Coulomb-nuclear interference region of momentum transfer, 9.0x10(-3)<-t<4.1x10(-2) (GeV/c)(2), was measured with a 21.7 GeV/c polarized proton beam at the Alternating Gradient Synchrotron of Brookhaven National Laboratory. The ratio of hadronic spin-flip to nonflip amplitude, r(5), was obtained from the analyzing power to be Rer(5)=0.088+/-0.058 and Imr(5)=-0.161+/-0.226. PMID:12144435

  12. Extraction of 10 sec/75 keV/70 A ion beams at prototype neutral beam injector unit for JT-60

    International Nuclear Information System (INIS)

    A prototype neutral beam injector for JT-60 was constructed to test and demonstrate a single beam line performance before fabrication of fourteen injector units for JT-60. The system has been operated over 4 months without serious troubles. Ion beams of 10 sec/75 keV/70 A were extracted repeatedly and most of design values were achieved. Accelerator grids were stable during 10 sec pulse, and other components of the system were confirmed to be sufficiently reliable. The system was also operated with a magnetic field which simulated a stray field from JT-60 tokamak. With the stray field applied, no choking effect in a drift tube like PLT or Culham effects were observed at all. (author)

  13. Emulsion Cloud Chamber technique to measure the fragmentation of a high-energy carbon beam

    CERN Document Server

    De Lellis, G; Buontempo, S; Capua, F D; Furusawa, Y; Lavina, L S; Marotta, A; Migliozzi, P; Naganawa, N; Petukhov, Yu P; Pistillo, C; Russo, A; Strolin, P; Tioukov, V; Toshito, T; Yasuda, N

    2007-01-01

    Beams of Carbon nuclei are now in use or planned to be used in various centers for cancer treatment around the world. The knowledge of the fragmentation of Carbon nuclei when they interact with the human body is important for evaluating of the spatial profile of their energy deposition in the tissues, hence the damage to tissues neighbouring the tumor. To this purpose, the identification of the fragmentation products is a key element. We present in this paper the charge measurement of about 3000 fragments produced by the interaction of $^{12}$C nuclei with an energy of 400 MeV/nucleon in a detector simulating the density of the human body. The nuclear emulsion technique is used, by means of the so-called Emulsion Cloud Chamber. The nuclear emulsions are inspected using fast automated microscopes recently developed. A charge assignment efficiency of more than 99% is achieved. The separation of Hydrogen, Helium, Lithium, Berillium, Boron and Carbon can be achieved at two standard deviations or considerably more...

  14. Deflection analysis of reinforced concrete beams strengthened with carbon fibre reinforced polymer under long-term load action

    Institute of Scientific and Technical Information of China (English)

    Mykolas DAUGEVI(C)IUS; Juozas VALIVONIS; Gediminas MAR(C)IUKAITIS

    2012-01-01

    This paper presents the results of an experimental research on reinforced concrete beams strengthened with an external carbon fibre reinforced polymer (CFRP) layer under long-term load action that lasted for 330 d.We describe the characteristics of deflection development of the beams strengthened with different additional anchorages of the external carbon fibre composite layer during the period of interest.The conducted experiments showed that the additional anchorage influences the slip of the extemal layer with respect to the strengthened element.Thus,concrete and carbon fibre composite interface stiffness decreases with a long-term load action.Therefore,the proposed method of analysis based on the built-up-bars theory can be used to estimate concrete and carbon fibre composite interface stiffness in the case of long-term load.

  15. An Intense $\\gamma$-ray Beam Line of 10 MeV Order Based on Compton Backscattering

    CERN Document Server

    Guo, W; Chen, J G; Lu, G C; Ma, Y G; Shen, W Q; Wang, C B; Wang, H W; Wei, Z Y; Xu, J Q; Xu, W; Xu, Y; Yan, Z; Yuan, R Y

    2006-01-01

    Shanghai Laser Electron Gamma Source, a $\\gamma$-ray beam line of 10MeV order was proposed recently. The beam line is expected to generate $\\gamma$-ray with maximum energy of 22MeV by backward Compton scattering between CO$_2$ laser and electron in the 3.5GeV storage ring of future Shanghai Synchrotron Radiation Facility. The flux of non-collimated $\\gamma$-ray can be 10$^9$ $\\sim$ 10$^{10}$s$^{-1}$ if a commercial CO$_2$ laser of 100W order output power is employed and injected with optimized settings.

  16. Production of clinically useful positron emitter beams during carbon ion deceleration

    Science.gov (United States)

    Lazzeroni, M.; Brahme, A.

    2011-03-01

    In external beam radiation therapy, radioactive beams offer the best clinical solution to simultaneously treat and in vivo monitor the dose delivery and tumor response using PET or PET-CT imaging. However, difficulties mainly linked to the low production efficiency have so far limited their use. This study is devoted to the analysis of the production of high energy 11C fragments, preferably by projectile fragmentation of a stable monodirectional and monoenergetic primary 12C beam in different absorbing materials (decelerators) in order to identify the optimal elemental composition. The study was performed using the Monte Carlo code SHIELD-HIT07. The track length and fluence of generated secondary particles were scored in a uniform absorber of 300 cm length and 10 cm radius, divided into slices of 1 cm thickness. The 11C fluence build-up and mean energy variation with increasing decelerator depth are presented. Furthermore, the fluence of the secondary 11C beam was studied as a function of its mean energy and the corresponding remaining range in water. It is shown that the maximum 11C fluence build-up is high in compounds where the fraction by weight of hydrogen is high, being the highest in liquid hydrogen. Furthermore, a cost effective alternative solution to the single medium initially envisaged is presented: a two-media decelerator that comprises a first liquid hydrogen section followed by a second decelerating section made of a hydrogen-rich material, such as polyethylene (C2H4). The purpose of the first section is to achieve a fast initial 11C fluence build-up, while the second section is primarily designed to modulate the mean energy of the generated 11C beam in order to reach the tumor depth. Finally, it was demonstrated that, if the intensity of the primary 12C beam can be increased by an order of magnitude, a sufficient intensity of the secondary 11C beam is achieved for therapy and subsequent therapeutic PET imaging sessions. Such an increase in the

  17. Electron-beam assisted selective growth of graphenic carbon thin films on SiO2/Si and quartz substrates

    OpenAIRE

    Knyazev, Maxim; Sedlovets, Daria; Trofimov, Oleg; Redkin, Arkady

    2015-01-01

    The first selective growth of graphenic carbon thin films on silicon dioxide is reported. A preliminary e-beam exposure of the substrate is found to strongly affect the process of such films growth. The emphasis is placed on the influence of substrate exposure on the rate of carbon deposition. The explanation of this effect is proposed. The data of electrical and optical measurements and the results of atomic force and scanning electron microscopy and Raman spectroscopy studies are reported. ...

  18. New onset of myasthenia gravis 10 years after proton beam therapy for thymoma.

    Science.gov (United States)

    Karasaki, Takahiro; Murakawa, Tomohiro; Nagayama, Kazuhiro; Nitadori, Jun-Ichi; Anraku, Masaki; Kikuchi, Yoshinao; Shinozaki-Ushiku, Aya; Igaki, Hiroshi; Nakajima, Jun

    2016-05-01

    A 36-year-old woman underwent proton beam therapy for encapsulated type B1 thymoma for curative intent at 66 GyE. Radiographically partial response was achieved. Although the tumor size had been stable since that time, she developed systemic myasthenia gravis 10 years after the proton therapy. Extended thymectomy was performed. There were no adhesions between the tumor and the pericardium, and there were no adhesions also between the tumor and the sternum, probably due to the favor of Bragg peak effect. Extensive hyalinization with small foci of viable tumor cells showing degenerated type A-like morphology was observed in the resected tumor. Whether the viable cells represented recurrence with degenerative changes or de novo tumor formation was unable to be determined, and whether the viable cells were responsible for the onset of myasthenia gravis remained unclear. PMID:25301055

  19. Induced photonuclear interaction by Rhodotron-TT200 10 MeV electron beam

    Indian Academy of Sciences (India)

    Farshid Tabbakh; Mojtaba Mostajab Aldaavati; Mahdieh Hoseyni; Khadijeh Rezaee Ebrahim Saraee

    2012-02-01

    In this paper the photonuclear interaction induced by 10 MeV electron beam generating high-intensity neutrons is studied. Since the results depend on the target material, the calculations are performed for Pb, Ta and W targets which have high , in a simple geometry. MCNPX code has been used to simulate the whole process. Also, the results of photon generation has been compared with the experimental results to evaluate the reliability of the calculation. The results show that the obtained neutron flux can reach up to 1012 n/cm2 /s with average energies of 0.9 MeV, 0.4 MeV and 0.9 MeV for these three elements respectively with the maximum heat deposited as 3000 W/c3,4500 W/c3 and 6000 W/c3.

  20. Simulation and optimization of a 10 A electron gun with electrostatic compression for the electron beam ion source

    International Nuclear Information System (INIS)

    Increasing the current density of the electron beam in the ion trap of the Electron Beam Ion Source (EBIS) in BNL's Relativistic Heavy Ion Collider facility would confer several essential benefits. They include increasing the ions’ charge states, and therefore, the ions’ energy out of the Booster for NASA applications, reducing the influx of residual ions in the ion trap, lowering the average power load on the electron collector, and possibly also reducing the emittance of the extracted ion beam. Here, we discuss our findings from a computer simulation of an electron gun with electrostatic compression for electron current up to 10 A that can deliver a high-current-density electron beam for EBIS. The magnetic field in the cathode-anode gap is formed with a magnetic shield surrounding the gun electrodes and the residual magnetic field on the cathode is (5 ÷ 6) Gs. It was demonstrated that for optimized gun geometry within the electron beam current range of (0.5 ÷ 10) A the amplitude of radial beam oscillations can be maintained close to 4% of the beam radius by adjusting the injection magnetic field generated by a separate magnetic coil. Simulating the performance of the gun by varying geometrical parameters indicated that the original gun model is close to optimum and the requirements to the precision of positioning the gun elements can be easily met with conventional technology.

  1. Simulation and optimization of a 10 A electron gun with electrostatic compression for the electron beam ion source.

    Science.gov (United States)

    Pikin, A; Beebe, E N; Raparia, D

    2013-03-01

    Increasing the current density of the electron beam in the ion trap of the Electron Beam Ion Source (EBIS) in BNL's Relativistic Heavy Ion Collider facility would confer several essential benefits. They include increasing the ions' charge states, and therefore, the ions' energy out of the Booster for NASA applications, reducing the influx of residual ions in the ion trap, lowering the average power load on the electron collector, and possibly also reducing the emittance of the extracted ion beam. Here, we discuss our findings from a computer simulation of an electron gun with electrostatic compression for electron current up to 10 A that can deliver a high-current-density electron beam for EBIS. The magnetic field in the cathode-anode gap is formed with a magnetic shield surrounding the gun electrodes and the residual magnetic field on the cathode is (5 ÷ 6) Gs. It was demonstrated that for optimized gun geometry within the electron beam current range of (0.5 ÷ 10) A the amplitude of radial beam oscillations can be maintained close to 4% of the beam radius by adjusting the injection magnetic field generated by a separate magnetic coil. Simulating the performance of the gun by varying geometrical parameters indicated that the original gun model is close to optimum and the requirements to the precision of positioning the gun elements can be easily met with conventional technology.

  2. Simulation and optimization of a 10 A electron gun with electrostatic compression for the electron beam ion source

    Energy Technology Data Exchange (ETDEWEB)

    Pikin, A.; Beebe, E. N.; Raparia, D. [Brookhaven National Laboratory, Upton, New York 11973 (United States)

    2013-03-15

    Increasing the current density of the electron beam in the ion trap of the Electron Beam Ion Source (EBIS) in BNL's Relativistic Heavy Ion Collider facility would confer several essential benefits. They include increasing the ions' charge states, and therefore, the ions' energy out of the Booster for NASA applications, reducing the influx of residual ions in the ion trap, lowering the average power load on the electron collector, and possibly also reducing the emittance of the extracted ion beam. Here, we discuss our findings from a computer simulation of an electron gun with electrostatic compression for electron current up to 10 A that can deliver a high-current-density electron beam for EBIS. The magnetic field in the cathode-anode gap is formed with a magnetic shield surrounding the gun electrodes and the residual magnetic field on the cathode is (5 Division-Sign 6) Gs. It was demonstrated that for optimized gun geometry within the electron beam current range of (0.5 Division-Sign 10) A the amplitude of radial beam oscillations can be maintained close to 4% of the beam radius by adjusting the injection magnetic field generated by a separate magnetic coil. Simulating the performance of the gun by varying geometrical parameters indicated that the original gun model is close to optimum and the requirements to the precision of positioning the gun elements can be easily met with conventional technology.

  3. Surface treatment of 0.20% C carbon steel by high-current pulsed electron beam

    Institute of Scientific and Technical Information of China (English)

    XU Guo-cheng; FU Shi-you; GUAN Qing-feng

    2006-01-01

    A high-current pulsed electron beam(HCPEB) generated on the system of Nadezhda-2 was applied to improve the microstructure and performance of 0.20% C low carbon steel. Surface layers of the samples bombarded by explosive electron beam at different pulses was observed by using electron microscopy. The physical model of the thermal-stress process and related modification mechanism as a result of HCPEB irradiation was also investigated. After HCPEB post treatments, obvious changes in microstructure and significant hardening occur in the depth of 200-250 μm from the surface after HCPEB irradiation. Rapid heating and subsequent rapid solidification induce heavy plastic deformation, which results in that the laminated structure of pearlite is substituted by dispersive rounded-like cementites in the near-surface. The effect of HCPEB treatment can reach more than 500 m depth from the surface. The original crystalline structure is changed to a different degree that grows with the numbers of bombardment, and in the surface layer amorphous states and nanocrystaline structures consisting of grains of γ-phase and cementite are found. The violent stress induced by HCPEB irradiation is the origin of the nanostructured and amorphous structure formation.

  4. Inferring phytoplankton carbon and eco-physiological rates from diel cycles of spectral particulate beam-attenuation coefficient

    Directory of Open Access Journals (Sweden)

    G. Dall'Olmo

    2011-11-01

    Full Text Available The diurnal fluctuations in solar irradiance impose a fundamental frequency on ocean biogeochemistry. Observations of the ocean carbon cycle at these frequencies are rare, but could be considerably expanded by measuring and interpreting the inherent optical properties. A method is presented to analyze diel cycles in particulate beam-attenuation coefficient (cp measured at multiple wavelengths. The method is based on fitting observations with a size-structured population model coupled to an optical model to infer the particle size distribution and physiologically relevant parameters of the cells responsible for the measured diel cycle in cp. Results show that the information related to size and contained in the spectral data can be exploited to independently estimate growth and loss rates during the day and night. In addition, the model can characterize the population of particles affecting the diel variability in cp. Application of this method to spectral cp measured at a station in the oligotrophic Mediterranean Sea suggests that most of the observed variations in cp can be ascribed to a synchronized population of cells with an equivalent spherical diameter around 4.6±1.5 μm. The inferred carbon biomass of these cells was about 5.2–6.0 mg m−3 and accounted for approximately 10% of the total particulate organic carbon. If successfully validated, this method may improve our in situ estimates of primary productivity.

  5. Reactions of a Be-10 beam on proton and deuteron targets

    CERN Document Server

    Schmitt, K T; Ahn, S; Bardayan, D W; Bey, A; Blackmon, J C; Brown, S M; Chae, K Y; Chipps, K A; Cizewski, J A; Hahn, K I; Kolata, J J; Kozub, R L; Liang, J F; Matei, C; Matos, M; Matyas, D; Moazen, B; Nesaraja, C D; Nunes, F M; Malley, P D O; Pain, S D; Peters, W A; Pittman, S T; Roberts, A; Shapira, D; Shriner, J F; Smith, M S; Spassova, I; Stracener, D W; Upadhyay, N J; Villano, A N; Wilson, G L

    2013-01-01

    The extraction of detailed nuclear structure information from transfer reactions requires reliable, well-normalized data as well as optical potentials and a theoretical framework demonstrated to work well in the relevant mass and beam energy ranges. It is rare that the theoretical ingredients can be tested well for exotic nuclei owing to the paucity of data. The halo nucleus Be-11 has been examined through the 10Be(d,p) reaction in inverse kinematics at equivalent deuteron energies of 12,15,18, and 21.4 MeV. Elastic scattering of Be-10 on protons was used to select optical potentials for the analysis of the transfer data. Additionally, data from the elastic and inelastic scattering of Be-10 on deuterons was used to fit optical potentials at the four measured energies. Transfers to the two bound states and the first resonance in Be-11 were analyzed using the Finite Range ADiabatic Wave Approximation (FR-ADWA). Consistent values of the spectroscopic factor of both the ground and first excited states were extrac...

  6. Integration of carbon nanotubes with semiconductor technology: fabrication of hybrid devices by III–V molecular beam epitaxy

    DEFF Research Database (Denmark)

    Stobbe, Søren; Lindelof, P. E.; Nygård, J.

    2006-01-01

    on incorporation of singlewall nanotubes in III–V semiconductor heterostructures grown by molecular beam epitaxy (MBE). We demonstrate that singlewall carbon nanotubes can be overgrown using MBE; electrical contacts to the nanotubes are obtained by GaMnAs grown at 250 °C. The resulting devices can exhibit field...

  7. Study of the time and space distribution of $\\beta^+$ emitters from $80\\ \\mega\\electronvolt/$u carbon ion beam irradiation on PMMA

    CERN Document Server

    Agodi, C; Cirrone, G A P; Collamati, F; Cuttone, G; De Lucia, E; De Napoli, M; Di Domenico, A; Faccini, R; Ferroni, F; Fiore, S; Gauzzi, P; Iarocci, E; Marafini, M; Mattei, I; Paoloni, A; Patera, V; Piersanti, L; Romano, F; Sarti, A; Sciubba, A; Voena, C

    2012-01-01

    Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments and the on-line knowledge of the Bragg peak position is still a matter of research. A possible technique exploits the collinear $511\\ \\kilo\\electronvolt$ photons produced by positrons annihilation from $\\beta^+$ emitters created by the beam. This paper reports rate measurements of the $511\\ \\kilo\\electronvolt$ photons emitted after the interactions of a $80\\ \\mega\\electronvolt / u$ fully stripped carbon ion beam at the Laboratori Nazionali del Sud (LNS) of INFN, with a Poly-methyl methacrylate target. The time evolution of the $\\beta^+$ rate was parametrized and the dominance of $^{11}C$ emitters over the other species ($^{13}N$, $^{15}O$, $^{14}O$) was observed, measuring the fraction of carbon ions activating $\\beta^+$ emitters $A_0=(10.3\\pm0.7)\\cdot10^{-3}$. The average depth in the PMMA of the positron annihilation from $\\beta^+$ emitters was also meas...

  8. Study of the time and space distribution of {beta}{sup +} emitters from 80MeV/u carbon ion beam irradiation on PMMA

    Energy Technology Data Exchange (ETDEWEB)

    Agodi, C. [Laboratori Nazionali del Sud dell' INFN, Catania (Italy); Bellini, F. [Dipartimento di Fisica, Sapienza Universita di Roma, Roma (Italy); INFN Sezione di Roma, Roma (Italy); Cirrone, G.A.P. [Laboratori Nazionali del Sud dell' INFN, Catania (Italy); Collamati, F. [Dipartimento di Fisica, Sapienza Universita di Roma, Roma (Italy); INFN Sezione di Roma, Roma (Italy); Cuttone, G. [Laboratori Nazionali del Sud dell' INFN, Catania (Italy); De Lucia, E. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); De Napoli, M. [Laboratori Nazionali del Sud dell' INFN, Catania (Italy); Di Domenico, A.; Faccini, R.; Ferroni, F. [Dipartimento di Fisica, Sapienza Universita di Roma, Roma (Italy); INFN Sezione di Roma, Roma (Italy); Fiore, S. [Dipartimento di Fisica, Sapienza Universita di Roma, Roma (Italy); Gauzzi, P. [Dipartimento di Fisica, Sapienza Universita di Roma, Roma (Italy); INFN Sezione di Roma, Roma (Italy); Iarocci, E. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Dipartimento di Scienze di Base e Applicate per l' Ingegneria, Sapienza Universita di Roma, Roma (Italy); Marafini, M., E-mail: michela.marafini@roma1.infn.it [Museo Storico della Fisica e Centro Studi e Ricerche ' E. Fermi' , Roma (Italy); Mattei, I. [Dipartimento di Fisica, Roma Tre Universita di Roma, Roma (Italy); Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Paoloni, A. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); and others

    2012-07-15

    Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments and the on-line knowledge of the Bragg peak position is still a matter of research. A possible technique exploits the collinear 511keV photons produced by positrons annihilation from {beta}{sup +} emitters created by the beam. This paper reports rate measurements of the 511keV photons emitted after the interactions of a 80MeV/u fully stripped carbon ion beam at the Laboratori Nazionali del Sud (LNS) of INFN, with a poly-methyl methacrylate target. The time evolution of the {beta}{sup +} rate was parametrized and the dominance of {sup 11}C emitters over the other species ({sup 13}N, {sup 15}O, {sup 14}O) was observed, measuring the fraction of carbon ions activating {beta}{sup +} emitters to be (10.3{+-}0.7) Multiplication-Sign 10{sup -3}. The average depth in the PMMA of the positron annihilation from {beta}{sup +} emitters was also measured, D{sub {beta}{sup +}}=5.3{+-}1.1mm, to be compared to the expected Bragg peak depth D{sub Bragg}=11.0{+-}0.5mm obtained from simulations.

  9. RBEs of thermal neutron beam and the 10B(n,α)7Li reaction on skin in the hamster

    International Nuclear Information System (INIS)

    The skin relative biologic effectiveness (RBE) of a thermal neutron beam and the 10B(n,α)7Li reaction were determined by using Syrian (Golden) hamsters and compared with the RBE of a 9-MeV electron beam. The boron used in our experiment was 10B-paraboronophenylalanine (10B-BPA). The Kyoto University Research Reactor was used as the source of thermal neutrons. In the skin dose-response curve, thermal neutron beams produced an almost linear relationship between the maximum skin reaction and the absorbed dose. The RBE obtained in this experimental system was about 2.0. The RBEs of the 14N(n,p)14C and the 10B(n,α)7Li reaction were estimated as 3.1 and about 1.6, respectively, with the assumption that each component of radiation was additive

  10. Radiosensitivity of pimonidazole-unlabelled intratumour quiescent cell population to γ-rays, accelerated carbon ion beams and boron neutron capture reaction.

    OpenAIRE

    Masunaga, S; Sakurai, Y.; Tanaka, H.; Hirayama, R; Matsumoto, Y; Uzawa, A; Suzuki, M.; Kondo, N; Narabayashi, M.; Maruhashi, A; Ono, K.

    2013-01-01

    [Objectives] To detect the radiosensitivity of intratumour quiescent (Q) cells unlabelled with pimonidazole to accelerated carbon ion beams and the boron neutron capture reaction (BNCR). [Methods] EL4 tumour-bearing C57BL/J mice received 5-bromo-2′-deoxyuridine (BrdU) continuously to label all intratumour proliferating (P) cells. After the administration of pimonidazole, tumours were irradiated with γ-rays, accelerated carbon ion beams or reactor neutron beams with the prior administration of...

  11. One-dimensional carbon nanostructures for terahertz electron-beam radiation

    Science.gov (United States)

    Tantiwanichapan, Khwanchai; Swan, Anna K.; Paiella, Roberto

    2016-06-01

    One-dimensional carbon nanostructures such as nanotubes and nanoribbons can feature near-ballistic electronic transport over micron-scale distances even at room temperature. As a result, these materials provide a uniquely suited solid-state platform for radiation mechanisms that so far have been the exclusive domain of electron beams in vacuum. Here we consider the generation of terahertz light based on two such mechanisms, namely, the emission of cyclotronlike radiation in a sinusoidally corrugated nanowire (where periodic angular motion is produced by the mechanical corrugation rather than an externally applied magnetic field), and the Smith-Purcell effect in a rectilinear nanowire over a dielectric grating. In both cases, the radiation properties of the individual charge carriers are investigated via full-wave electrodynamic simulations, including dephasing effects caused by carrier collisions. The overall light output is then computed with a standard model of charge transport for two particularly suitable types of carbon nanostructures, i.e., zigzag graphene nanoribbons and armchair single-wall nanotubes. Relatively sharp emission peaks at geometrically tunable terahertz frequencies are obtained in each case. The corresponding output powers are experimentally accessible even with individual nanowires, and can be scaled to technologically significant levels using array configurations. These radiation mechanisms therefore represent a promising paradigm for light emission in condensed matter, which may find important applications in nanoelectronics and terahertz photonics.

  12. Increased Tensile Strength of Carbon Nanotube Yarns and Sheets through Chemical Modification and Electron Beam Irradiation

    Science.gov (United States)

    Miller, Sandi G.; Williams, Tiffany S.; Baker, James S.; Sola, Francisco; Lebron-Colon, Marisabel; McCorkle, Linda S.; Wilmoth, Nathan G.; Gaier, James; Chen, Michelle; Meador, Michael A.

    2014-01-01

    The inherent strength of individual carbon nanotubes offers considerable opportunity for the development of advanced, lightweight composite structures. Recent work in the fabrication and application of carbon nanotube (CNT) forms such as yarns and sheets has addressed early nanocomposite limitations with respect to nanotube dispersion and loading; and has pushed the technology toward structural composite applications. However, the high tensile strength of an individual CNT has not directly translated to macro-scale CNT forms where bulk material strength is limited by inter-tube electrostatic attraction and slippage. The focus of this work was to assess post processing of CNT sheet and yarn to improve the macro-scale strength of these material forms. Both small molecule functionalization and e-beam irradiation was evaluated as a means to enhance tensile strength and Youngs modulus of the bulk CNT material. Mechanical testing results revealed a tensile strength increase in CNT sheets by 57 when functionalized, while an additional 48 increase in tensile strength was observed when functionalized sheets were irradiated; compared to unfunctionalized sheets. Similarly, small molecule functionalization increased yarn tensile strength up to 25, whereas irradiation of the functionalized yarns pushed the tensile strength to 88 beyond that of the baseline yarn.

  13. Measurement of large angle fragments induced by 400 MeV n-1 carbon ion beams

    Science.gov (United States)

    Aleksandrov, Andrey; Consiglio, Lucia; De Lellis, Giovanni; Di Crescenzo, Antonia; Lauria, Adele; Montesi, Maria Cristina; Patera, Vincenzo; Sirignano, Chiara; Tioukov, Valeri

    2015-09-01

    The use of carbon ion beams in radiotherapy presents significant advantages when compared to traditional x-ray. In fact, carbon ions deposit their energy inside the human body at the end of their range, the Bragg peak. Unlike x-ray beams, where the energy deposition decreases exponentially inside the irradiated volume, the shape of carbon beams is sharp and focused. Advantages are an increased energy released in the cancer volume while minimizing the irradiation to healthy tissues. Currently, the use of carbon beams is limited by the poor knowledge we have about the effects of the secondary fragments on the irradiated tissues. The secondary particles produced and their angular distribution is crucial to determine the global dose deposition. The knowledge of the flux of secondary particles plays a key role in the real time monitoring of the dose profile in hadron therapy. We present a detector based on nuclear emulsions for fragmentation measurements that performs a sub-micrometric tridimensional spatial resolution, excellent multi-particle separation and large angle track recognition. Nuclear emulsions are assembled in order to realize a hybrid detector (emulsion cloud chamber (ECC)) made of 300 μm nuclear emulsion films alternated with lead as passive material. Data reported here have been obtained by exposing two ECC detectors to the fragments produced by a 400 MeV n-1 12C beam on a composite target at the GSI laboratory in Germany. The ECC was exposed inside a more complex detector, named FIRST, in order to collect fragments with a continuous angular distribution in the range 47°-81° with respect to the beam axis. Results on the angular distribution of fragments as well as their momentum estimations are reported here.

  14. Development and characterization of a 2D scintillation detector for quality assurance in scanned carbon ion beams

    Science.gov (United States)

    Tamborini, A.; Raffaele, L.; Mirandola, A.; Molinelli, S.; Viviani, C.; Spampinato, S.; Ciocca, M.

    2016-04-01

    At the Centro Nazionale di Adroterapia Oncologica (CNAO Foundation), a two-dimensional high resolution scintillating dosimetry system has been developed and tested for daily Quality Assurance measurements (QA) in carbon ion radiotherapy with active scanning technique, for both single pencil beams and scanned fields produced by a synchrotron accelerator. The detector consists of a thin plane organic scintillator (25×25 cm2, 2 mm thick) coupled with a high spatial resolution CCD camera (0.25 mm) in a light-tight box. A dedicated Labview software was developed for image acquisition triggered with the beam extraction, data post-processing and analysis. The scintillator system was preliminary characterized in terms of short-term reproducibility (found to be within±0.5%), linearity with the number of particles (linear fit χ2 = 0.996) and dependence on particle flux (measured to be < 1.5 %). The detector was then tested for single beam spot measurements (Full Width at Half Maximum and position) and for 6×6 cm2 reference scanned field (determination of homogeneity) for carbon ions with energy from 115 MeV/u up to 400 MeV/u. No major differences in the investigated beam parameters measured with scintillator system and the radiochromic EBT3 reference films were observed. The system allows therefore real-time monitoring of the carbon ion beam relevant parameters, with a significant daily time saving with respect to films currently used. The results of this study show the suitability of the scintillation detector for daily QA in a carbon ion facility with an active beam delivery system.

  15. Measurement of large angle fragments induced by 400 MeV n−1 carbon ion beams

    International Nuclear Information System (INIS)

    The use of carbon ion beams in radiotherapy presents significant advantages when compared to traditional x-ray. In fact, carbon ions deposit their energy inside the human body at the end of their range, the Bragg peak. Unlike x-ray beams, where the energy deposition decreases exponentially inside the irradiated volume, the shape of carbon beams is sharp and focused. Advantages are an increased energy released in the cancer volume while minimizing the irradiation to healthy tissues. Currently, the use of carbon beams is limited by the poor knowledge we have about the effects of the secondary fragments on the irradiated tissues. The secondary particles produced and their angular distribution is crucial to determine the global dose deposition. The knowledge of the flux of secondary particles plays a key role in the real time monitoring of the dose profile in hadron therapy.We present a detector based on nuclear emulsions for fragmentation measurements that performs a sub-micrometric tridimensional spatial resolution, excellent multi-particle separation and large angle track recognition. Nuclear emulsions are assembled in order to realize a hybrid detector (emulsion cloud chamber (ECC)) made of 300 μm nuclear emulsion films alternated with lead as passive material.Data reported here have been obtained by exposing two ECC detectors to the fragments produced by a 400 MeV n−1 12C beam on a composite target at the GSI laboratory in Germany. The ECC was exposed inside a more complex detector, named FIRST, in order to collect fragments with a continuous angular distribution in the range 47°–81° with respect to the beam axis. Results on the angular distribution of fragments as well as their momentum estimations are reported here. (paper)

  16. Dynamic response of RC beams strengthened with near surface mounted Carbon-FRP rods subjected to damage

    Science.gov (United States)

    Capozucca, R.; Blasi, M. G.; Corina, V.

    2015-07-01

    Near surface mounted (NSM) technique with fiber reinforced polymer (FRP) is becoming a common method in the strengthening of concrete beams. The availability of NSM FRP technique depends on many factors linked to materials and geometry - dimensions of the rods used, type of FRP material employed, rods’ surface configuration, groove size - and to adhesion between concrete and FRP rods. In this paper detection of damage is investigated measuring the natural frequency values of beam in the case of free-free ends. Damage was due both to reduction of adhesion between concrete and carbon-FRP rectangular and circular rods and cracking of concrete under static bending tests on beams. Comparison between experimental and theoretical frequency values evaluating frequency changes due to damage permits to monitor actual behaviour of RC beams strengthened by NSM CFRP rods.

  17. Measurement of analyzing power for proton-carbon elastic scattering in the Coulomb-nuclear interference region with a 22-GeV/c polarized proton beam

    International Nuclear Information System (INIS)

    The analyzing power for proton-carbon elastic scattering in the Coulomb-nuclear interference region of momentum transfer, 9.0x10-3-2 (GeV/c)2, was measured with a 21.7 GeV/c polarized proton beam at the Alternating Gradient Synchrotron of Brookhaven National Laboratory. The ratio of hadronic spin-flip to nonflip amplitude, r5, was obtained from the analyzing power to be Rer5=0.088±0.058 and Imr5=-0.161±0.226

  18. Robust, easily shaped, and epoxy-free carbon-fiber-aluminum cathodes for generating high-current electron beams

    Science.gov (United States)

    Liu, Lie; Li, Limin; Wen, Jianchun; Wan, Hong

    2009-02-01

    This paper presents the construction of carbon-fiber-aluminum (CFA) cathode by squeezing casting and its applications for generating high-current electron beams to drive high-power microwave sources. The fabrication process avoided using epoxy, a volatile deteriorating the vacuum system. These cathodes had a higher hardness than conventional aluminum, facilitating machining. After surface treatment, carbon fibers became the dominator determining emission property. A multineedle CFA cathode was utilized in a triode virtual cathode oscillator (vircator), powered by a ˜450 kV, ˜400 ns pulse. It was found that 300-400 MW, ˜250 ns microwave was radiated at a dominant frequency of 2.6 GHz. Further, this cathode can endure high-current-density emission without detectable degradation in performance as the pulse shot proceeded, showing the robust nature of carbon fibers as explosive emitters. Overall, this new class of cold cathodes offers a potential prospect of developing high-current electron beam sources.

  19. Deposition of Diamond-Like carbon Films by High-Intensity Pulsed Ion Beam Ablation at Various Substrate Temperatures

    Institute of Scientific and Technical Information of China (English)

    梅显秀; 刘振民; 马腾才; 董闯

    2003-01-01

    Diamond-like carbon (DLC) films have been deposited on to Si substrates at substrate temperatures from 25℃to 400 ℃ by a high-intensity pulsed-ion-beam (HIPIB) ablation deposition technique. The formation of DLC is confirmed by Raman spectroscopy. According to an x-ray photoelectron spectroscopy analysis, the concentration of spa carbon in the films is about 40% when the substrate temperature is below 300 ℃. With increasing substrate temperature from 25 ℃ to 400 ℃, the concentration of sp3 carbon decreases from 43% to 8%. In other words,sp3 carbon is graphitized into sp2 carbon when the substrate temperature is above 300 ℃. The results of xray diffraction and atomic force microscopy show that, with increasing the substrate temperature, the surface roughness and the friction coefficient increase, and the microhardness and the residual stress of the films decrease.

  20. Chemical effects of 100 keV primary electrons in an e-beam sustained carbon dioxide laser discharge

    International Nuclear Information System (INIS)

    The dissociation of carbon dioxide and the reaction of carbon monoxide with oxygen caused by a high-energy (approx 100 kev) electron beam in a typical carbon dioxide laser gas mixture has been observed. The variation of reaction rates with electron energy and current, interelectrode spacing, and gas composition has been studied. The rates of both processes suggest that the reactions are caused by unthermalized secondary electrons. The conditions were investigated under which the carbon monoxide oxidation reaction could be used to offset dissociation in a laser and thus prolong its sealed life. For a secondary to primary current ratio of one hundred this condition should be satisfied for any practical device. A sealed run was carried out which demonstrated that dissociation by secondary electrons could be offset by the oxidation of carbon monoxide by the primary electrons. (author)

  1. Generation and diagnostics of pulsed intense ion beams with an energy density of 10 J/cm{sup 2}

    Energy Technology Data Exchange (ETDEWEB)

    Isakova, Yu., E-mail: isakova-yulia@tpu.ru; Pushkarev, A.; Khailov, I. [Tomsk Polytechnic University, 30, Lenin Ave., 634050 Tomsk (Russian Federation); Zhong, H., E-mail: zhonghaowen@buaa.edu.cn [Beihang University, Beijing 100191 (China)

    2015-07-15

    The paper presents the results of a study on transportation and focusing of a pulsed ion beam at gigawatt power level, generated by a diode with explosive-emission cathode. The experiments were carried out with the TEMP-4M accelerator operating in double-pulse mode: the first pulse is of negative polarity (500 ns, 100-150 kV), and this is followed by a second pulse of positive polarity (120 ns, 200-250 kV). To reduce the beam divergence, we modified the construction of the diode. The width of the anode was increased compared to that of the cathode. We studied different configurations of planar and focusing strip diodes. It was found that the divergence of the ion beam formed by a planar strip diode, after construction modification, does not exceed 3° (half-angle). Modification to the construction of a focusing diode made it possible to reduce the beam divergence from 8° to 4°-5°, as well as to increase the energy density at the focus up to 10-12 J/cm{sup 2}, and decrease the shot to shot variation in the energy density from 10%-15% to 5%-6%. When measuring the ion beam energy density above the ablation threshold of the target material (3.5-4 J/cm{sup 2}), we used a metal mesh with 50% transparency to lower the energy density. The influence of the metal mesh on beam transport has been studied.

  2. Beam pen lithography based on arrayed polydimethylsiloxane (PDMS) micro-pyramids spin-coated with carbon black photo-resist

    International Nuclear Information System (INIS)

    This paper presents a new method for preparing a polydimethylsiloxane (PDMS) mold which can be used in beam pen lithography for patterning a photo-resist (PR) layer in a maskless and direct-write manner. The PDMS mold contains an array of micro-pyramids on its surface and is spin-coated with a layer of carbon black PR which is an opaque material. Because of the arrayed pyramidal surface profile, the spin-coated carbon black PR layer is either thinner at the pyramid tips or does not cover the tips at all, which allows ultraviolet (UV) light to pass through the PDMS mold and forms an array of UV beams. The aperture size of the UV beams can be controlled at a sub-micrometer scale and hence can be used for micro/nano-patterning. Applying this carbon black-PR-coated PDMS mold in beam pen lithography along with a metal lift-off process, various metal dot patterns with a dot-size around 400 to 500 nm are successfully obtained. Both experimental results and theoretical analysis are given along with possible improvements and applications in the future. (paper)

  3. Structural changes of electron and ion beam-deposited contacts in annealed carbon-based electrical devices

    KAUST Repository

    Batra, Nitin M

    2015-10-09

    The use of electron and ion beam deposition to make devices containing discrete nanostructures as interconnectors is a well-known nanofabrication process. Classically, one-dimensional materials such as carbon nanotubes (CNTs) have been electrically characterized by resorting to these beam deposition methods. While much attention has been given to the interconnectors, less is known about the contacting electrodes (or leads). In particular, the structure and chemistry of the electrode–interconnector interface is a topic that deserves more attention, as it is critical to understand the device behavior. Here, the structure and chemistry of Pt electrodes, deposited either with electron or ion beams and contacted to a CNT, are analyzed before and after thermally annealing the device in a vacuum. Free-standing Pt nanorods, acting as beam-deposited electrode models, are also characterized pre- and post-annealing. Overall, the as-deposited leads contain a non-negligible amount of amorphous carbon that is consolidated, upon heating, as a partially graphitized outer shell enveloping a Pt core. This observation raises pertinent questions regarding the definition of electrode–nanostructure interfaces in electrical devices, in particular long-standing assumptions of metal-CNT contacts fabricated by direct beam deposition methods.

  4. Conversion from dose-to-graphite to dose-to-water in an 80 MeV/A carbon ion beam.

    Science.gov (United States)

    Rossomme, S; Palmans, H; Shipley, D; Thomas, R; Lee, N; Romano, F; Cirrone, P; Cuttone, G; Bertrand, D; Vynckier, S

    2013-08-21

    Based on experiments and numerical simulations, a study is carried out pertaining to the conversion of dose-to-graphite to dose-to-water in a carbon ion beam. This conversion is needed to establish graphite calorimeters as primary standards of absorbed dose in these beams. It is governed by the water-to-graphite mass collision stopping power ratio and fluence correction factors, which depend on the particle fluence distributions in each of the two media. The paper focuses on the experimental and numerical determination of this fluence correction factor for an 80 MeV/A carbon ion beam. Measurements have been performed in the nuclear physics laboratory INFN-LNS in Catania (Sicily, Italy). The numerical simulations have been made with a Geant4 Monte Carlo code through the GATE simulation platform. The experimental data are in good agreement with the simulated results for the fluence correction factors and are found to be close to unity. The experimental values increase with depth reaching 1.010 before the Bragg peak region. They have been determined with an uncertainty of 0.25%. Different numerical results are obtained depending on the level of approximation made in calculating the fluence correction factors. When considering carbon ions only, the difference between measured and calculated values is maximal just before the Bragg peak, but its value is less than 1.005. The numerical value is close to unity at the surface and increases to 1.005 near the Bragg peak. When the fluence of all charged particles is considered, the fluence correction factors are lower than unity at the surface and increase with depth up to 1.025 before the Bragg peak. Besides carbon ions, secondary particles created due to nuclear interactions have to be included in the analysis: boron ions ((10)B and (11)B), beryllium ions ((7)Be), alpha particles and protons. At the conclusion of this work, we have the conversion of dose-to-graphite to dose-to-water to apply to the response of a graphite

  5. Characterization of nanometer-scale porosity in reservoir carbonate rock by focused ion beam-scanning electron microscopy.

    Science.gov (United States)

    Bera, Bijoyendra; Gunda, Naga Siva Kumar; Mitra, Sushanta K; Vick, Douglas

    2012-02-01

    Sedimentary carbonate rocks are one of the principal porous structures in natural reservoirs of hydrocarbons such as crude oil and natural gas. Efficient hydrocarbon recovery requires an understanding of the carbonate pore structure, but the nature of sedimentary carbonate rock formation and the toughness of the material make proper analysis difficult. In this study, a novel preparation method was used on a dolomitic carbonate sample, and selected regions were then serially sectioned and imaged by focused ion beam-scanning electron microscopy. The resulting series of images were used to construct detailed three-dimensional representations of the microscopic pore spaces and analyze them quantitatively. We show for the first time the presence of nanometer-scale pores (50-300 nm) inside the solid dolomite matrix. We also show the degree of connectivity of these pores with micron-scale pores (2-5 μm) that were observed to further link with bulk pores outside the matrix.

  6. Flexural behaviour of partially bonded carbon fibre reinforced polymers strengthened concrete beams: Application to fire protection systems design

    International Nuclear Information System (INIS)

    Highlights: • The mechanical behaviour of partially bonded CFRP strengthened beams was modelled. • Two dimensional non-linear finite element models were developed. • Partially bonded beams can present similar flexural strength to fully bonded ones. • Relations between the bonded length and the strength reduction were proposed. • The proposed relations were used for the design of fire protection systems. - Abstract: Recent fire resistance tests on reinforced concrete (RC) beams strengthened with carbon fibre reinforced polymers (CFRP) laminates showed that it is possible to attain considerable fire endurance provided that thermal insulation is applied at the anchorage zones of the strengthening system. With such protection, although the CFRP laminate prematurely debonds in the central part of the beam, it transforms into a cable fixed at the extremities until one of the anchorage zones loses its bond strength. The main objective of this paper is to propose a simplified methodology for the design of fire protection systems for CFRP strengthened-RC beams, which is based on applying thicker insulation at the anchorage zones (promoting the above mentioned “cable behaviour”) and a thinner one at the current zone (avoiding tensile rupture of the carbon fibres). As a first step towards the validation of this methodology, finite element (FE) models were developed to simulate the flexural behaviour at ambient temperature of full-scale RC beams strengthened with CFRP laminates according to the externally bonded reinforcement (EBR) and near surface mounted (NSM) techniques, in both cases fully or partially bonded (the latter simulating the cable). The FE models were calibrated with results of 4-point bending tests on small-scale beams and then extended for different beam geometries, with spans (L) varying from 2 m to 5 m, in which the influence of the CFRP bonded length (lb) and the loading type (point or uniformly distributed) on the strength reduction was

  7. Gorsky effect and diffusion of carbon in grade VT1-0 titanium

    International Nuclear Information System (INIS)

    By means of transmitting electron microscopy one showed the presence of metastable phase formations on the basis of carbon related coherently to matrix in VT1-0 titanium. Within 300-550 deg C temperature range when conducting three-point bending testings one observe the Gorsky effect by carbon determined at reverse deformation of creep. One justified the techniques enabling to determine diffusion coefficient of intrusion impurity causing the Gorsky effect. Using that technique one determined the diffusion efficient coefficients of carbon within 300-550 deg C range in VT1-0 specimens with grain various size. It is shown that in the ultrafinely-grain state (grain size is about 0.3 μm) the grain-boundary diffusion is the basic mechanism of carbon diffusion. One determined activation energy values of grain-boundary and volume diffusion of carbon equal to 103 and 177 kJ/mole

  8. Water equivalent thickness values of materials used in beams of protons, helium, carbon and iron ions

    OpenAIRE

    Zhang, Rui; Taddei, Phillip J.; Fitzek, Markus M.; Newhauser, Wayne D.

    2010-01-01

    Heavy charged particle beam radiotherapy for cancer is of increasing interest because it delivers a highly conformal radiation dose to the target volume. Accurate knowledge of the range of a heavy charged particle beam after it penetrates a patient’s body or other materials in the beam line is very important and is usually stated in terms of the water equivalent thickness (WET). However, methods of calculating WET for heavy charged particle beams are lacking. Our objective was to test several...

  9. SU-F-BRD-10: Lung IMRT Planning Using Standardized Beam Bouquet Templates

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, L; Wu, Q J.; Yin, F [Duke University Medical Center, Durham, NC (United States); Ge, Y [University of North Carolina at Charlotte, Charlotte, NC (United States)

    2014-06-15

    Purpose: We investigate the feasibility of choosing from a small set of standardized templates of beam bouquets (i.e., entire beam configuration settings) for lung IMRT planning to improve planning efficiency and quality consistency, and also to facilitate automated planning. Methods: A set of beam bouquet templates is determined by learning from the beam angle settings in 60 clinical lung IMRT plans. A k-medoids cluster analysis method is used to classify the beam angle configuration into clusters. The value of the average silhouette width is used to determine the ideal number of clusters. The beam arrangements in each medoid of the resulting clusters are taken as the standardized beam bouquet for the cluster, with the corresponding case taken as the reference case. The resulting set of beam bouquet templates was used to re-plan 20 cases randomly selected from the database and the dosimetric quality of the plans was evaluated against the corresponding clinical plans by a paired t-test. The template for each test case was manually selected by a planner based on the match between the test and reference cases. Results: The dosimetric parameters (mean±S.D. in percentage of prescription dose) of the plans using 6 beam bouquet templates and those of the clinical plans, respectively, and the p-values (in parenthesis) are: lung Dmean: 18.8±7.0, 19.2±7.0 (0.28), esophagus Dmean: 32.0±16.3, 34.4±17.9 (0.01), heart Dmean: 19.2±16.5, 19.4±16.6 (0.74), spinal cord D2%: 47.7±18.8, 52.0±20.3 (0.01), PTV dose homogeneity (D2%-D99%): 17.1±15.4, 20.7±12.2 (0.03).The esophagus Dmean, cord D02 and PTV dose homogeneity are statistically better in the plans using the standardized templates, but the improvements (<5%) may not be clinically significant. The other dosimetric parameters are not statistically different. Conclusion: It's feasible to use a small number of standardized beam bouquet templates (e.g. 6) to generate plans with quality comparable to that of clinical

  10. SU-F-BRD-10: Lung IMRT Planning Using Standardized Beam Bouquet Templates

    International Nuclear Information System (INIS)

    Purpose: We investigate the feasibility of choosing from a small set of standardized templates of beam bouquets (i.e., entire beam configuration settings) for lung IMRT planning to improve planning efficiency and quality consistency, and also to facilitate automated planning. Methods: A set of beam bouquet templates is determined by learning from the beam angle settings in 60 clinical lung IMRT plans. A k-medoids cluster analysis method is used to classify the beam angle configuration into clusters. The value of the average silhouette width is used to determine the ideal number of clusters. The beam arrangements in each medoid of the resulting clusters are taken as the standardized beam bouquet for the cluster, with the corresponding case taken as the reference case. The resulting set of beam bouquet templates was used to re-plan 20 cases randomly selected from the database and the dosimetric quality of the plans was evaluated against the corresponding clinical plans by a paired t-test. The template for each test case was manually selected by a planner based on the match between the test and reference cases. Results: The dosimetric parameters (mean±S.D. in percentage of prescription dose) of the plans using 6 beam bouquet templates and those of the clinical plans, respectively, and the p-values (in parenthesis) are: lung Dmean: 18.8±7.0, 19.2±7.0 (0.28), esophagus Dmean: 32.0±16.3, 34.4±17.9 (0.01), heart Dmean: 19.2±16.5, 19.4±16.6 (0.74), spinal cord D2%: 47.7±18.8, 52.0±20.3 (0.01), PTV dose homogeneity (D2%-D99%): 17.1±15.4, 20.7±12.2 (0.03).The esophagus Dmean, cord D02 and PTV dose homogeneity are statistically better in the plans using the standardized templates, but the improvements (<5%) may not be clinically significant. The other dosimetric parameters are not statistically different. Conclusion: It's feasible to use a small number of standardized beam bouquet templates (e.g. 6) to generate plans with quality comparable to that of clinical

  11. Commissioning of a compact laser-based proton beam line for high intensity bunches around 10Â MeV

    Science.gov (United States)

    Busold, S.; Schumacher, D.; Deppert, O.; Brabetz, C.; Kroll, F.; Blažević, A.; Bagnoud, V.; Roth, M.

    2014-03-01

    We report on the first results of experiments with a new laser-based proton beam line at the GSI accelerator facility in Darmstadt. It delivers high current bunches at proton energies around 9.6 MeV, containing more than 109 particles in less than 10 ns and with tunable energy spread down to 2.7% (ΔE/E0 at FWHM). A target normal sheath acceleration stage serves as a proton source and a pulsed solenoid provides for beam collimation and energy selection. Finally a synchronous radio frequency (rf) field is applied via a rf cavity for energy compression at a synchronous phase of -90 deg. The proton bunch is characterized at the end of the very compact beam line, only 3 m behind the laser matter interaction point, which defines the particle source.

  12. Evaluation of beam delivery and ripple filter design for non-isocentric proton and carbon ion therapy

    International Nuclear Information System (INIS)

    This study aims at selecting and evaluating a ripple filter design compatible with non-isocentric proton and carbon ion scanning beam treatment delivery for a compact nozzle. The use of non-isocentric treatments when the patient is shifted as close as possible towards the nozzle exit allows for a reduction in the air gap and thus an improvement in the quality of scanning proton beam treatment delivery. Reducing the air gap is less important for scanning carbon ions, but ripple filters are still necessary for scanning carbon ion beams to reduce the number of energy steps required to deliver homogeneous SOBP. The proper selection of ripple filters also allows a reduction in the possible transverse and depth-dose inhomogeneities that could appear in non-isocentric conditions in particular.A thorough review of existing ripple filter designs over the past 16 years is performed and a design for non-isocentric treatment delivery is presented. A unique ripple filter quality index (QIRiFi) independent of the particle type and energy and representative of the ratio between energy modulation and induced scattering is proposed. The Bragg peak width evaluated at the 80% dose level (BPW80) is proposed to relate the energy modulation of the delivered Bragg peaks and the energy layer step size allowing the production of homogeneous SOBP. Gate/Geant4 Monte Carlo simulations have been validated for carbon ion and ripple filter simulations based on measurements performed at CNAO and subsequently used for a detailed analysis of the proposed ripple filter design.A combination of two ripple filters in a series has been validated for non-isocentric delivery and did not show significant transverse and depth-dose inhomogeneities. Non-isocentric conditions allow a significant reduction in the spot size at the patient entrance (up to 350% and 200% for protons and carbon ions with range shifter, respectively), and therefore in the lateral penumbra in the patients. (paper)

  13. Evaluation of beam delivery and ripple filter design for non-isocentric proton and carbon ion therapy

    Science.gov (United States)

    Grevillot, L.; Stock, M.; Vatnitsky, S.

    2015-10-01

    This study aims at selecting and evaluating a ripple filter design compatible with non-isocentric proton and carbon ion scanning beam treatment delivery for a compact nozzle. The use of non-isocentric treatments when the patient is shifted as close as possible towards the nozzle exit allows for a reduction in the air gap and thus an improvement in the quality of scanning proton beam treatment delivery. Reducing the air gap is less important for scanning carbon ions, but ripple filters are still necessary for scanning carbon ion beams to reduce the number of energy steps required to deliver homogeneous SOBP. The proper selection of ripple filters also allows a reduction in the possible transverse and depth-dose inhomogeneities that could appear in non-isocentric conditions in particular. A thorough review of existing ripple filter designs over the past 16 years is performed and a design for non-isocentric treatment delivery is presented. A unique ripple filter quality index (QIRiFi) independent of the particle type and energy and representative of the ratio between energy modulation and induced scattering is proposed. The Bragg peak width evaluated at the 80% dose level (BPW80) is proposed to relate the energy modulation of the delivered Bragg peaks and the energy layer step size allowing the production of homogeneous SOBP. Gate/Geant4 Monte Carlo simulations have been validated for carbon ion and ripple filter simulations based on measurements performed at CNAO and subsequently used for a detailed analysis of the proposed ripple filter design. A combination of two ripple filters in a series has been validated for non-isocentric delivery and did not show significant transverse and depth-dose inhomogeneities. Non-isocentric conditions allow a significant reduction in the spot size at the patient entrance (up to 350% and 200% for protons and carbon ions with range shifter, respectively), and therefore in the lateral penumbra in the patients.

  14. Monte Carlo validation of the TrueBeam 10XFFF phase–space files for applications in lung SABR

    Energy Technology Data Exchange (ETDEWEB)

    Teke, Tony, E-mail: tteke2@bccancer.bc.ca [Medical Physics, BC Cancer Agency—Centre for the Southern Interior, Kelowna, British Columbia V1Y 5L3 (Canada); Duzenli, Cheryl; Bergman, Alanah; Viel, Francis; Atwal, Parmveer; Gete, Ermias [Medical Physics, BC Cancer Agency—Vancouver Centre, Vancouver, British Columbia V5Z 4E6 (Canada)

    2015-12-15

    Purpose: To establish the clinical acceptability of universal Monte Carlo phase–space data for the 10XFFF (flattening filter free) photon beam on the Varian TrueBeam Linac, including previously unreported data for small fields, output factors, and inhomogeneous media. The study was particularly aimed at confirming the suitability for use in simulations of lung stereotactic ablative radiotherapy treatment plans. Methods: Monte Carlo calculated percent depth doses (PDDs), transverse profiles, and output factors for the TrueBeam 10 MV FFF beam using generic phase–space data that have been released by the Varian MC research team were compared with in-house measurements and published data from multiple institutions (ten Linacs from eight different institutions). BEAMnrc was used to create field size specific phase–spaces located underneath the jaws. Doses were calculated with DOSXYZnrc in a water phantom for fields ranging from 1 × 1 to 40 × 40 cm{sup 2}. Particular attention was paid to small fields (down to 1 × 1 cm{sup 2}) and dose per pulse effects on dosimeter response for high dose rate 10XFFF beams. Ion chamber measurements were corrected for changes in ion collection efficiency (P{sub ion}) with increasing dose per pulse. MC and ECLIPSE ANISOTROPIC ANALYTICAL ALGORITHM (AAA) calculated PDDs were compared to Gafchromic film measurement in inhomogeneous media (water, bone, lung). Results: Measured data from all machines agreed with Monte Carlo simulations within 1.0% and 1.5% for PDDs and in-field transverse profiles, respectively, for field sizes >1 × 1 cm{sup 2} in a homogeneous water phantom. Agreements in the 80%–20% penumbra widths were better than 2 mm for all the fields that were compared. For all the field sizes considered, the agreement between their measured and calculated output factors was within 1.1%. Monte Carlo results for dose to water at water/bone, bone/lung, and lung/water interfaces as well as within lung agree with film

  15. Monte Carlo validation of the TrueBeam 10XFFF phase–space files for applications in lung SABR

    International Nuclear Information System (INIS)

    Purpose: To establish the clinical acceptability of universal Monte Carlo phase–space data for the 10XFFF (flattening filter free) photon beam on the Varian TrueBeam Linac, including previously unreported data for small fields, output factors, and inhomogeneous media. The study was particularly aimed at confirming the suitability for use in simulations of lung stereotactic ablative radiotherapy treatment plans. Methods: Monte Carlo calculated percent depth doses (PDDs), transverse profiles, and output factors for the TrueBeam 10 MV FFF beam using generic phase–space data that have been released by the Varian MC research team were compared with in-house measurements and published data from multiple institutions (ten Linacs from eight different institutions). BEAMnrc was used to create field size specific phase–spaces located underneath the jaws. Doses were calculated with DOSXYZnrc in a water phantom for fields ranging from 1 × 1 to 40 × 40 cm2. Particular attention was paid to small fields (down to 1 × 1 cm2) and dose per pulse effects on dosimeter response for high dose rate 10XFFF beams. Ion chamber measurements were corrected for changes in ion collection efficiency (Pion) with increasing dose per pulse. MC and ECLIPSE ANISOTROPIC ANALYTICAL ALGORITHM (AAA) calculated PDDs were compared to Gafchromic film measurement in inhomogeneous media (water, bone, lung). Results: Measured data from all machines agreed with Monte Carlo simulations within 1.0% and 1.5% for PDDs and in-field transverse profiles, respectively, for field sizes >1 × 1 cm2 in a homogeneous water phantom. Agreements in the 80%–20% penumbra widths were better than 2 mm for all the fields that were compared. For all the field sizes considered, the agreement between their measured and calculated output factors was within 1.1%. Monte Carlo results for dose to water at water/bone, bone/lung, and lung/water interfaces as well as within lung agree with film measurements to within 2.8% for 10

  16. Carbon ion beam treatment in patients with primary and recurrent sacrococcygeal chordoma

    Energy Technology Data Exchange (ETDEWEB)

    Uhl, Matthias; Jensen, Alexandra; Herfarth, Klaus [University of Heidelberg, Department of Radiation Oncology, Heidelberg (Germany); Heidelberg Ion Beam Therapy Center (HIT), Heidelberg (Germany); Welzel, Thomas [University of Heidelberg, Department of Radiation Oncology, Heidelberg (Germany); Ellerbrock, Malte; Haberer, Thomas [Heidelberg Ion Beam Therapy Center (HIT), Heidelberg (Germany); Jaekel, Oliver [University of Heidelberg, Department of Radiation Oncology, Heidelberg (Germany); Heidelberg Ion Beam Therapy Center (HIT), Heidelberg (Germany); German Cancer Research Center (dkfz), Heidelberg (Germany); Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg (Germany); Debus, Juergen [University of Heidelberg, Department of Radiation Oncology, Heidelberg (Germany); Heidelberg Ion Beam Therapy Center (HIT), Heidelberg (Germany); German Cancer Research Center (dkfz), Heidelberg (Germany); Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg (Germany); Deutsches Konsortium fuer Translationale Krebsforschung (DKTK), Heidelberg (Germany)

    2015-07-15

    The purpose of this work was to evaluate the results of high-dose radiation treatment using carbon ion therapy, alone or combined with intensity-modulated radiation treatment (IMRT), in patients with sacral chordoma. Between 2009 and 2012, 56 patients with sacral chordoma were treated in our center. The tumor was located above S3 in 33 patients and in S3 or below in 23 patients. In all, 41 patients received radiation therapy for the primary tumor, while 15 patients were treated for the recurrent tumor. Toxicity was measured using NCI CTCAE v.4.03. Local control (LC) and overall survival (OS) were evaluated with the Kaplan-Meier method. A total of 23 patients were irradiated with carbon ions in combination with photon IMRT, while 33 received carbon ion therapy only. Forty-three patients had a macroscopic tumor at treatment start with a median tumor size (GTV) of 244 ml (range 5-1188 ml). The median total dose was 66 Gy (range 60-74 Gy; RBE). After a median follow-up time of 25 months, the 2- and 3-year local control probability was 76 % and 53 %, respectively. The overall survival rate was 100 %. Treatment for primary tumor and male patients resulted in significant better local control. No higher toxicity occurred within the follow-up time. High-dose photon/carbon ion beam radiation therapy is safe and, especially for primary sacral chordomas, highly effective. A randomized trial is required to evaluate the role of primary definitive hypofractionated particle therapy compared with surgery with or without adjuvant radiotherapy. (orig.) [German] Evaluierung der Ergebnisse nach hochdosierter Kohlenstoffionentherapie, allein oder in Kombination mit einer intensitaetsmodulierten Photonenbestrahlung (IMRT), bei Patienten mit einem sakralen Chordom. Zwischen 2009 und 2012 wurden 56 Patienten mit sakralen Chordomen in unserem Zentrum behandelt. Der Tumor war bei 33 Patienten oberhalb von S3 und bei 23 Patienten auf Hoehe von S3 oder unterhalb davon lokalisiert. Insgesamt

  17. Secondary organic carbon quantification and source apportionment of PM10 in Kaifeng, China

    Institute of Scientific and Technical Information of China (English)

    WU Lin; FENG Yinchang; WU Jianhui; ZHU Tan; BI Xiaohui; HAN Bo; YANG Weihong; YANG Zhiqiang

    2009-01-01

    During 2005, the filter samples of ambient PM10 from five sites and the source samples of particulate matter were collected in Kaifeng, Henan province of China. Nineteen elements, water-soluble ions, total carbon (TC) and organic carbon (OC) contained in samples were analyzed. Seven contributive source types were identified and their contributions to ambient PM10 were estimated by chemical mass balance (CMB) receptor model. Weak associations between the concentrations of organic carbon and element carbon (EC) were observed during the sampling periods, indicating that there was secondary organic aerosol pollution in the urban atmosphere. An indirect method of "OC/EC minimum ratio" was applied to estimate the concentration of secondary organic carbon (SOC). The results showed that SOC contributed 26.2%, 32.4% and 18.0% of TC in spring, summer-fall and winter respectively, and the annual average SOC concentration was 7.07 μg/m3, accounting for 5.73% of the total mass in ambient PM10. The carbon species concentrations in ambient PM10 were recalculated by subtracting the SOC concentrations from measured concentrations of TC and OC to increase the compatibility of source and receptor measurements for CMB model.

  18. MODIFICATION OF CARBON STEEL BY LASER SURFACE MELTING: PART I: EFFECT OF LASER BEAM TRAVELLING SPEED ON MICROSTRUCTURAL FEATURES AND SURFACE HARDNESS

    OpenAIRE

    Hashem F. El-Labban; Abdelaziz, M.; Essam R.I. Mahmoud

    2013-01-01

    The present study aims to improve the surface hardness of carbon steel by application of laser surface melting of effective conditions. The travelling speed of laser beam during this treatment is one of the important treatment conditions. This study aims to investigate the effect of laser surface melting with different beam speeds on macro and microstructure as well as the hardness distribution through the thickness of carbon steel. To achieve this target, three different travelling speeds (1...

  19. Very high temperature chemical vapor deposition of new carbon thin films using organic semiconductor molecular beam sources

    Energy Technology Data Exchange (ETDEWEB)

    Noguchi, Takuya [Department of Chemistry, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033 (Japan); Shimada, Toshihiro, E-mail: shimada@chem.s.u-tokyo.ac.j [Department of Chemistry, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033 (Japan); Hanzawa, Akinori; Hasegawa, Tetsuya [Department of Chemistry, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033 (Japan)

    2009-11-30

    We carried out the preparation and characterization of new carbon films deposited using an organic molecular beam deposition apparatus with very high substrate temperature (from room temperature to 2670 K), which we newly developed. When we irradiated molecular beam of organic semiconductor perylene tetracarboxylic acid dianhydride (PTCDA) on Y{sub 0.07}Zr{sub 0.93}O{sub 2} (111) at 2170 K, a new carbon material was formed via decomposition and fusing of the molecules. The films were characterized with an atomic force microscope (AFM), Raman spectroscopy, X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). Zirconium carbide (ZrC) films were identified beneath the topmost carbon layer by XRD and XPS analyses, which results from chemical reactions of the substrate and the molecules. Partially graphitized aromatic rings of PTCDA were observed from Raman spectroscopy. The present technique - very high temperature chemical vapor deposition using organic semiconductor sources - will be useful to study a vast unexplored field of covalent carbon solids.

  20. Performance of three pencil-type ionization chambers (10 cm) in computed tomography standard beams

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Maysa C. de; Xavier, Marcos; Caldas, Linda V.E., E-mail: mcastro@ipen.br, E-mail: mxavier@ipen.br, E-mail: lcaldas@ipen.br [Instituto de Pesquisas Energeticas e Nucleres (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    The use of computed tomography (CT) has increased over the years, thus generating a concern about the doses received by patients undergoing this procedure. Therefore, it is necessary to perform routinely beam dosimetry with the use of a pencil-type ionization chamber. This detector is the most utilized in the procedures of quality control tests on this kind of equipment. The objective of this work was to perform some characterization tests in standard CT beams, as the saturation curve, polarity effect, ion collection efficiency and linearity of response, using three ionization chambers, one commercial and two developed at the IPEN. (author)

  1. Performance of three pencil-type ionization chambers (10 cm) in computed tomography standard beams

    Science.gov (United States)

    de Castro, Maysa C.; Xavier, Marcos; Caldas, Linda V. E.

    2016-07-01

    The use of computed tomography (CT) has increased over the years, thus generating a concern about the doses received by patients undergoing this procedure. Therefore, it is necessary to perform routinely beam dosimetry with the use of a pencil-type ionization chamber. This detector is the most utilized in the procedures of quality control tests on this kind of equipment. The objective of this work was to perform some characterization tests in standard CT beams, as the saturation curve, polarity effect, ion collection efficiency and linearity of response, using three ionization chambers, one commercial and two developed at the IPEN.

  2. Diallyl disulfide enhances carbon ion beams-induced apoptotic cell death in cervical cancer cells through regulating Tap73 /ΔNp73.

    Science.gov (United States)

    Di, Cuixia; Sun, Chao; Li, Hongyan; Si, Jing; Zhang, Hong; Han, Lu; Zhao, Qiuyue; Liu, Yang; Liu, Bin; Miao, Guoying; Gan, Lu; Liu, Yuanyuan

    2015-01-01

    Diallyl disulfide (DADS), extracted from crushed garlic by steam-distillation, has been reported to provide the anticancer activity in several cancer types. However, the effect of DADS on high-LET carbon beams - induced cell death remains unknown. Therefore, we used human cervical cancer cells to elucidate the molecular effects of this diallyl sulfide. Radiotherapy remains the mainstay of treatment, especially in advanced cervical cancer and there is still space to improve the radiosensitivity to reduce radiation dosage. In this study, we found that radiation effects evoked by high-LET carbon beam was marked by inhibition of cell viability, cell cycle arrest, significant rise of apoptotic cells, regulation of transcription factor, such as p73, as well as alterations of crucial mediator of the apoptosis pathway. We further demonstrated that pretreatment of 10 µM DADS in HeLa cells exposed to radiation resulted in decrease in cell viability and increased radiosensitivity. Additionally, cells pretreated with DADS obviously inhibited the radiation-induced G2/M phase arrest, but promoted radiation-induced apoptosis. Moreover, combination DADS and the radiation exacerbated the activation of apoptosis pathways through up-regulated ration of pro-apoptotic Tap73 to anti-apoptotic ΔNp73, and its downstream proteins, such as FASLG, and APAF1. Taken together, these results suggest that DADS is a potential candidate as radio sensitive agent for cervical cancer. PMID:26505313

  3. Effects of porous carbon additives and induced fluorine on low dielectric constant polyimide synthesized with an e-beam

    International Nuclear Information System (INIS)

    We report the synthesis of a polyimide matrix with a low dielectric constant for application as an intercalation material between metal interconnections in electronic devices. Porous activated carbon was embedded in the polyimide to reduce the dielectric constant, and a thin film of the complex was obtained using the spin-coating and e-beam irradiation methods. The surface of the thin film was modified with fluorine functional groups to impart water resistance and reduce the dielectric constant further. The water resistance was significantly improved by the modification with hydrophobic fluorine groups. The dielectric constant was effectively decreased by porous activated carbon. The fluorine modification also resulted in a low dielectric constant on the polyimide surface by reducing the polar surface free energy. The dielectric constant of polyimide film decreased from 2.98 to 1.9 by effects of porous activated carbon additive and fluorine surface modification.

  4. Friction and Wear of Ion-Beam-Deposited Diamondlike Carbon on Chemical-Vapor-Deposited, Fine-Grain Diamond

    Science.gov (United States)

    Miyoshi, Kazuhisa; Wu, Richard L. C.; Lanter, William C.

    1996-01-01

    Friction and wear behavior of ion-beam-deposited diamondlike carbon (DLC) films coated on chemical-vapor-deposited (CVD), fine-grain diamond coatings were examined in ultrahigh vacuum, dry nitrogen, and humid air environments. The DLC films were produced by the direct impact of an ion beam (composed of a 3:17 mixture of Ar and CH4) at ion energies of 1500 and 700 eV and an RF power of 99 W. Sliding friction experiments were conducted with hemispherical CVD diamond pins sliding on four different carbon-base coating systems: DLC films on CVD diamond; DLC films on silicon; as-deposited, fine-grain CVD diamond; and carbon-ion-implanted, fine-grain CVD diamond on silicon. Results indicate that in ultrahigh vacuum the ion-beam-deposited DLC films on fine-grain CVD diamond (similar to the ion-implanted CVD diamond) greatly decrease both the friction and wear of fine-grain CVD diamond films and provide solid lubrication. In dry nitrogen and in humid air, ion-beam-deposited DLC films on fine-grain CVD diamond films also had a low steady-state coefficient of friction and a low wear rate. These tribological performance benefits, coupled with a wider range of coating thicknesses, led to longer endurance life and improved wear resistance for the DLC deposited on fine-grain CVD diamond in comparison to the ion-implanted diamond films. Thus, DLC deposited on fine-grain CVD diamond films can be an effective wear-resistant, lubricating coating regardless of environment.

  5. Zn-10.2% Fe coating over carbon steel atmospheric corrosion resistance. Comparison with zinc coating

    International Nuclear Information System (INIS)

    Zn-10.2% Fe galvanized coating versus hot galvanized coating over carbon steel corrosion performance has been studied. Different periods of atmospheric exposures in various Valencia Community sites, and salt spray accelerated test have been done. Carbon steel test samples have been used simultaneously in order to classify exposure atmosphere corrosivity, and environmental exposure atmosphere characteristics have been analyzed. Corrosion Velocity versus environmental parameters has been obtained. (Author) 17 refs

  6. Fresnel absorption of 1 μm- and 10 μm-laser beams at the keyhole wall during laser beam welding: Comparison between smooth and wavy surfaces

    International Nuclear Information System (INIS)

    The angle-dependent absorption of laser beams at metal surfaces is described by the Fresnel-equations. During keyhole laser welding the essential interaction takes place at very striping angles of incidence of the order of 1-8 degrees at the front of the vapour capillary, called the keyhole. For a smooth vapour capillary, laser beams with a wavelength of about 1 μm operate in a Fresnel-regime where the absorptance increases with the angle of incidence at the wall, towards the weak Brewster-angle maximum. In contrast, for 10 μm-lasers high absorptance around the more pronounced Brewster-angle peak takes place. From high speed imaging keyhole surface waves were observed. Mathematical modelling of the laser-keyhole interaction demonstrates that already relatively little waviness of the melt surface at the keyhole strongly modulates the angles of incidence and in turn the Fresnel-absorption due to varying angles of incidence, soon also leading to shadow zones. Due to this local variation of the angle of incidence the absorptance tends towards the angle-averaged value, with the consequence that for 1 μm-lasers the direct absorptance and in turn the penetration depth increases, particularly at low welding speed, while for 10 μm-lasers it generally decreases.

  7. Resist and Exposure Processes for Sub-10-nm Electron and Ion Beam Lithography

    NARCIS (Netherlands)

    Sidorkin, V.A.

    2010-01-01

    The research work described in this thesis deals with studying the ultimate resolution capabilities of electron and ion beam lithography (EBL and IBL respectively) with a focus on resist and exposure processes. The aim of this research was to enlarge knowledge and improve methods on the formation of

  8. Low-dose (10-Gy) total skin electron beam therapy for cutaneous T-cell lymphoma

    DEFF Research Database (Denmark)

    Kamstrup, Maria R; zbr735, zbr735; Iversen, Lars;

    2015-01-01

    PURPOSE: Cutaneous T-cell lymphomas (CTCLs) are dominated by mycosis fungoides (MF) and Sézary syndrome (SS), and durable disease control is a therapeutic challenge. Standard total skin electron beam therapy (TSEBT) is an effective skin-directed therapy, but the possibility of retreatments...

  9. Experimental study of the water-to-air stopping power ratio of monoenergetic carbon ion beams for particle therapy

    Science.gov (United States)

    Sánchez-Parcerisa, D.; Gemmel, A.; Jäkel, O.; Parodi, K.; Rietzel, E.

    2012-06-01

    Reference dosimetry with ionization chambers requires a number of chamber-specific and beam-specific calibration factors. For carbon ion beams, IAEA report TRS-398 yields a total uncertainty of 3% in the determination of the absorbed dose to water, for which the biggest contribution arises from the water-to-air stopping power ratio (sw, air), with an uncertainty of 2%. The variation of (sw, air) along the treatment field has been studied in several Monte Carlo works presented over the last few years. Their results were, in all cases, strongly dependent on the choice of mean ionization potentials (I-values) for air and water. A smaller dependence of (sw, air) with penetration depth was observed. Since a consensus on Iw, air and Iair has not yet been reached, the validity of such studies for clinical use cannot be assessed independently. Our approach is based on a direct experimental measurement of water-equivalent thicknesses of different air gaps at different beam energies. A theoretical expression describing the variation of the stopping power ratio with kinetic energy, sw,air(E), was derived from the Bethe-Bloch formula and fit to the measured data, yielding a coherent pair of Iw and Iair values with Iair/Iw = 1.157 ± 0.023. Additionally, the data from five different beam energies were combined in an average value of sw,air = 1.132 ± 0.003 (statistical) ± 0.003 (variation over energy range), valid for monoenergetic carbon ion beams at the plateau area of the depth dose distribution. A detailed uncertainty analysis was performed on the data, in order to assess the limitations of the method, yielding an overall standard uncertainty below 1% in sw,air(E). Therefore, when properly combined with the appropriate models for the fragment spectra, our experimental work can contribute to narrow the uncertainty margins currently in use in absorbed dose to water determination for dosimetry of carbon ion beam radiotherapy.

  10. Extended high order sandwich panel theory for bending analysis of sandwich beams with carbon nanotube reinforced face sheets

    Science.gov (United States)

    Jedari Salami, S.

    2016-02-01

    Bending analysis of a sandwich beam with soft core and carbon nanotube reinforced composite (CNTRC) face sheets in the literature is presented based on Extended High order Sandwich Panel Theory (EHSAPT). Distribution of fibers through the thickness of the face sheets could be uniform or functionally graded (FG). In this theory the face sheets follow the first order shear deformation theory (FSDT). Besides, the two dimensional elasticity is used for the core. The field equations are derived via the Ritz based solution which is suitable for any essential boundary condition. The influences of boundary conditions on bending response of the sandwich panel with soft core and CNTRC face sheet are investigated. In each type of boundary condition the effect of distribution pattern of CNTRCs on many essential involved parameters of the sandwich beam with functionally graded carbon nanotube reinforced composite (FG- CNTRC) face sheets are studied in detail. Finally, experimental result have been compared with those obtained based on developed solution method. It is concluded that, the sandwich beam with X distribution figure of face sheets is the strongest with the smallest transverse displacement, and followed by the UD, O and ∧-ones, respectively.

  11. Reinforced concrete T-beams externally prestressed with unbonded carbon fiber-reinforced polymer tendons

    DEFF Research Database (Denmark)

    Bennitz, Anders; Nilimaa, Jonny; Ravn, Dorthe Lund;

    2012-01-01

    force, and the presence of a deviator were investigated. The results were compared to those observed with analogous beams prestressed with steel tendons, common beam theory, and predictions made using an analytical model adapted from the literature. It was found that steel and CFRP tendons had very...

  12. Comparison of Head Scatter Factor for 6MV and 10MV flattened (FB) and Unflattened (FFF) Photon Beam using indigenously Designed Columnar Mini Phantom.

    Science.gov (United States)

    Ashokkumar, Sigamani; Nambi Raj, N Arunai; Sinha, Sujit Nath; Yadav, Girigesh; Thiyagarajan, Rajesh; Raman, Kothanda; Mishra, Manindra Bhushan

    2014-07-01

    To measure and compare the head scatter factor for flattened (FB) and unflattened (FFF) of 6MV and 10MV photon beam using indigenously designed mini phantom. A columnar mini phantom was designed as recommended by AAPM Task Group 74 with low and high atomic number materials at 10 cm (mini phantom) and at approximately twice the depth of maximum dose water equivalent thickness (brass build-up cap). Scatter in the accelerator (Sc) values of 6MV-FFF photon beams are lesser than that of the 6MV-FB photon beams (0.66-2.8%; Clinac iX, 2300CD) and (0.47-1.74%; True beam) for field sizes ranging from 10 × 10 cm(2) to 40 × 40 cm(2). Sc values of 10MV-FFF photon beams are lesser (0.61-2.19%; True beam) than that of the 10MV-FB photons beams for field sizes ranging from 10 × 10 cm(2) to 40 × 40 cm(2). The SSD had no influence on head scatter for both flattened and unflattened beams and irrespective of head design of the different linear accelerators. The presence of field shaping device influences the Sc values. The collimator exchange effect reveals that the opening of the upper jaw increases Sc irrespective of FB or FFF photon beams and different linear accelerators, and it is less significant in FFF beams. Sc values of 6MV-FB square field were in good agreement with that of AAPM, TG-74 published data for Varian (Clinac iX, 2300CD) accelerator. Our results confirm that the removal of flattening filter decreases in the head scatter factor compared to flattened beam. This could reduce the out-of-field dose in advanced treatment delivery techniques.

  13. Using of beam spoilers in linear accelerators with photons of 10 MV; Empleo de degradadores del haz en aceleradores lineales con fotones de 10 MV

    Energy Technology Data Exchange (ETDEWEB)

    Sansogne, R.; Palacios, V.; Arbiser, S. [Vidt Centro Medico- CETRO. Vidt 1924- (1428) Buenos Aires (Argentina)

    1998-12-31

    This work come along of the necessity to utilize an unique High-Energy Electron Linear Accelerator (10 MV) for radiant treatments which require higher doses in the surface levels of tissue. It is analyzed the interposition of acrylic degraders (spoilers) in the beam, especially for opposed and parallel fields in the cases of head and neck. It was analyzed the possible combinations of the following parameters: 1) Field sizes defined at isocenter (100 cm) 6 x 6 cm{sup 2}, 8 x 8 cm{sup 2} and 10 x 10 cm{sup 2} ; 2) Surface-spoiler distance (DSS) of 4, 7 and 10 cm; 3) Spoilers with different thickness 1.1 and 1.5 cm. It was observed a displacement of the maximum dose toward the surface, and an increase in the percentile doses in the build-up zone when the spoiler is nearing and/or increasing its thickness. It is verified that the use of spoilers, support the symmetry and plane of the beam inside of the clinically acceptable margins. When the results obtained are analyzed then it is proposed as a calculation method to incorporate an attenuation factor. (Author)

  14. Study on reinforced concrete beams strengthened using shape memory alloy wires in combination with carbon-fiber-reinforced polymer plates

    Science.gov (United States)

    Li, Hui; Liu, Zhi-qiang; Ou, Jin-ping

    2007-12-01

    It has been proven that carbon-fiber-reinforced polymer (CFRP) sheets or plates are capable of improving the strength of reinforced concrete (RC) structures. However, residual deformation of RC structures in service reduces the effect of CFRP strengthening. SMA can be applied to potentially decrease residual deformation and even close concrete cracks because of its recovery forces imposed on the concrete when heated. Therefore, a method of a RC structure strengthened by CFRP plates in combination with SMA wires is proposed in this paper. The strengthening effect of this method is investigated through experiments and numerical study based on the nonlinear finite element software ABAQUS in simple RC beams. Parametric analysis and assessment of damage by defining a damage index are carried out. The results indicate that recovery forces of SMA wires can decrease deflections and even close cracks in the concrete. The recovery rate of deflection of the beam increases with increasing the ratio of SMA wires. The specimen strengthened with CFRP plates has a relatively large stiffness and smaller damage index value when the residual deformation of the beam is first reduced by activation of the SMA wires. The effectiveness of this strengthening method for RC beams is verified by experimental and numerical results.

  15. Beam optics of a 10-cm diameter high current heavy ion diode

    International Nuclear Information System (INIS)

    Typically a large diameter surface ionization source is used to produce > 0.5 A K+ current with emittance < 1 π-mm-mrad for heavy ion fusion experiments. So far we have observed aberrations that are slightly different from those predicted by computer simulations. We have now set up an experiment to study in detail the beam optics of such a large diameter ion diode and to benchmark the simulation code

  16. Proton, Helium and Carbon Radiation Beam Targeting Reactive Oxygen, Nitrogen and Halogenated Species in TRIM-SRIM Model

    International Nuclear Information System (INIS)

    Nowadays proton beam radiation therapy is considered in few centers for management of malignancies. This study is aimed to explore the effect of proton, helium or carbon irradiation on free radicals. This study was conducted in department of Physiology/Medical physics, College of Medicine, Al-Mustansiriya University in Baghdad, Iraq during October 2009. TRIM-SRIM software version 1998 and2003 were used for computed Bragg peak and for calculated the effect of proton, helium and carbon ions against free radicals related to oxygen, nitrogen and halogen species. The lowest stopping power near Bragg's peak of proton targeting free radicals was against superoxide anion and its curve (the stopping power against energy) was shifted down while that of peroxynitrite(ONOO-) was shifted up. The stopping powers of helium targeting all studied free radicals were lower than corresponding proton irradiation but it required higher energy. Lower stopping power of carbon irradiation targeted hydroxyl(OH-) and halogenated radicals than the other reactive species were observed. It concludes that such from of external beam irradiation is associated with direct scavenging effect on free radicals of whatever sources.

  17. Effects of E-Beam Irradiation on the Chemical, Physical, and Electrochemical Properties of Activated Carbons for Electric Double-Layer Capacitors

    OpenAIRE

    Min-Jung Jung; Mi-Seon Park; Young-Seak Lee

    2015-01-01

    Activated carbons (ACs) were modified via e-beam irradiation at various doses for use as an electrode material in electric double-layer capacitors (EDLCs). The chemical compositions of the AC surfaces were largely unchanged by the e-beam irradiation. The ACs treated with the e-beam at radiation doses of 200 kGy exhibited higher nanocrystallinity than the untreated ACs. The specific surface areas and pore volumes of the e-beam irradiated ACs were also higher than those of the untreated ACs. Th...

  18. Formation of nanoscale carbon structures in the surface layer of metals under the impact of high intensity ion beam

    Energy Technology Data Exchange (ETDEWEB)

    Remnev, G.E., E-mail: remnev@hvd.tpu.ru [High-Voltage Research Institute at Tomsk Polytechnic University, 2a Lenin Ave., Tomsk 634028 (Russian Federation); Uglov, V.V., E-mail: uglov@bsu.by [Belarusian State University, 4 Nezavisimosti Ave., Minsk 220030 (Belarus); Shymanski, V.I. [Belarusian State University, 4 Nezavisimosti Ave., Minsk 220030 (Belarus); Pavlov, S.K. [High-Voltage Research Institute at Tomsk Polytechnic University, 2a Lenin Ave., Tomsk 634028 (Russian Federation); Kuleshov, A.K. [Belarusian State University, 4 Nezavisimosti Ave., Minsk 220030 (Belarus)

    2014-08-15

    Highlights: • Carbide phases in metals were formed by high-intense pulsed ion beam (HPIB) impact. • Tungsten and titanium carbides are characterized by nanoscale dimensions. • Carbides formation in surface layer provides its hardening. - Abstract: This work represents the results of phase composition and the mechanical properties of tungsten and titanium after high-intensity pulsed ion beam (HPIB) treatment. It was shown that nanoscale carbide particles are formed under the HPIB influence in the surface layers of metals. Raising the pulse number results in increase of volume fraction of the carbide phases. The microhardness is 1.5–2 times more than the initial value and wear resistance of the metals improves in response to alloying of tungsten and titanium with carbon atoms accompanied by the formation of carbides.

  19. Study the structure of neutron deficient carbon isotopes: 10C and 11C. Elastic and inelastic scattering on proton target

    International Nuclear Information System (INIS)

    This work is devoted to the study of the structure of neutron-deficient carbon isotopes: 10C and 11C. A theoretical model predicts a special behaviour for these nuclei: different deformations for neutron and proton densities. To test these predictions and to obtain information on the structure of these nuclei, we measured angular distribution for elastic and inelastic scattering on proton target with inverse kinematics at 40 MeV per nucleon. The angular distribution is deduced from the proton energy and angle scattering, measured by the MUST detector. Experimental set-up is completed with plastic detectors for scattered nucleus identification and with two CATS detectors for measurement of position and angle for each beam particle on the target. Angular distributions are calculated with an analytic method. This method is tested with a simulation and with 12C + p scattering analysis. Angular distributions are analysed in terms of a complex microscopic potential JLM with different microscopic matter densities. Elastic scattering gives an information on 10C and 11C matter root mean square radii. Both radii are larger than the one for the stable 12C isotope. Inelastic scattering is treated in DWBA approximation with microscopic transition densities. 10C inelastic scattering gives an information on neutron contribution of nucleus excitation. With 11C inelastic scattering, we could constrain transition densities and we could extract an information on the type of the transition. However, it is very difficult to confirm or to annul predictions of different deformations for proton and neutrons densities. (author)

  20. Generation of oxygen, carbon and metallic ion beams by a compact microwave source

    International Nuclear Information System (INIS)

    A small microwave ion source fabricated from a quartz tube and enclosed externally by a cavity has been operated with different geometries and for various gases in a cw mode. This source has been used to generate oxygen ion beams with energy as low as 5.5 eV. Beam energy spread has been measured to be less than 1 eV. By installing different metal plates on the front extraction electrode, metallic ion beams such as (Be, Cu, Al, etc.) can be produced

  1. Phase space generation for proton and carbon ion beams for external users’ applications at the Heidelberg Ion Therapy Center

    Directory of Open Access Journals (Sweden)

    Thomas eTessonnier

    2016-01-01

    Full Text Available In the field of radiation therapy, accurate and robust dose calculation is required. For this purpose, precise modeling of the irradiation system and reliable computational platforms are needed. At the Heidelberg Ion Therapy Center (HIT, the beamline has been already modeled in the FLUKA Monte Carlo code. However, this model was kept confidential for disclosure reasons and was not available for any external team. The main goal of this study was to create efficiently phase space (PS files for proton and carbon ion beams, for all energies and foci available at HIT. PS are representing the characteristics of each particle recorded (charge, mass, energy, coordinates, direction cosines, generation at a certain position along the beam path. In order to achieve this goal, keeping a reasonable data size but maintaining the requested accuracy for the calculation, we developed a new approach of beam PS generation with the Monte-Carlo code FLUKA. The generated PS were obtained using an infinitely narrow beam and recording the desired quantities after the last element of the beamline, with a discrimination of primaries or secondaries. In this way, a unique PS can be used for each energy to accommodate the different foci by combining the narrow-beam scenario with a random sampling of its theoretical Gaussian beam in vacuum. PS can also reproduce the different patterns from the delivery system, when properly combined with the beam scanning information. MC simulations using PS have been compared to simulations including the full beamline geometry and have been found in very good agreement for several cases (depth dose distributions, lateral dose profiles, with relative dose differences below 0.5%. This approach has also been compared with measured data of ion beams with different energies and foci, resulting in a very satisfactory agreement. Hence, the proposed approach was able to fulfill the different requirements and has demonstrated its capability for

  2. Measurement of the analyzing power for proton-carbon elastic scattering in the CNI region with a 22 GeV/c polarized proton beam

    International Nuclear Information System (INIS)

    We have carried out the experiment BNL-AGS E950 to measure the analyzing power for proton-carbon elastic scattering in the Coulomb-Nuclear Interference (CNI) region with a 22 GeV/c polarized proton beam. Recoil carbons from 300 keV to a few MeV in the CNI region, were detected inside the AGS ring to identify proton-carbon elastic scattering. The preliminary results of the analyzing power measurement are presented

  3. Carbon-10: Example of cyclotron production of positron emitters as an open research field

    DEFF Research Database (Denmark)

    Alves, F.; Lima, J.J.P.; Nickles, R.J.;

    2007-01-01

    This paper supports the thesis that significant improvement of PET output response to clinical questions can be achieved by innovation in radionuclide production. Moreover, that development can be performed with the resources available at a clinical centre. Carbon-10 production parameters studies...

  4. Resonant Enhancement of Coherent Phonons in Carbon Nanotubes Observed with Sub-10fs Time Resolution

    Directory of Open Access Journals (Sweden)

    Yanagi K.

    2013-03-01

    Full Text Available Using wavelength-resolved pump-probe spectroscopy with a sub-10-fs laser, we investigated resonant enhancement of radial breathing mode and G-mode coherent phonons in carbon nanotubes (CNTs, and successfully distinguished the electronic states of CNTs with different chiralities.

  5. Vacuum Electron-Beam Evaporation of Fe Nanocrystals on Si3N4 Buffer Layer for carbon Nanotube Growth

    Institute of Scientific and Technical Information of China (English)

    万青; 王太宏; 林成鲁

    2003-01-01

    Vacuum electron-beam evaporated iron nanocrystal is used for the growth of carbon nanotubes. Atomic force microscopy and Raman scattering studies reveal the formation of beta-iron silicide islands on bare silicon substrate after annealing at 700°C in N2 ambient. In order to eliminate the influence of iron-silicon interaction, Si3N4 buffer layer with the thickness of 80 nm is used. This technical route prevents effectively the formation of iron silicide and improves the quality of the iron nanocrystals. Using these iron nanocrystals with high density (about 7 × 1010/cm2) as catalyst, high-density multiwall carbon nanotubes are synthesized on Si3N4/Si substrate.

  6. Formation of Carbonized Polystyrene Sphere/hemisphere Shell Arrays by Ion Beam Irradiation and Subsequent Annealing or Chloroform Treatment

    Science.gov (United States)

    Song, Xianyin; Dai, Zhigao; Xiao, Xiangheng; Li, Wenqing; Zheng, Xudong; Shang, Xunzhong; Zhang, Xiaolei; Cai, Guangxu; Wu, Wei; Meng, Fanli; Jiang, Changzhong

    2015-01-01

    Heat-resistant two-dimensional (2D) sphere/hemisphere shell array is significant for the fabrication of novel nanostructures. Here large-area, well-ordered arrays of carbonized polystyrene (PS) hollow sphere/hemisphere with controlled size and morphology are prepared by combining the nanosphere self-assembly, kV Ag ion beam modification, and subsequent annealing or chloroform treatment. Potential mechanisms for the formation and evolution of the heat-resistant carbonized PS spherical shell with increasing ion fluence and energy are discussed. Combined with noble metal or semiconductor, these modified PS sphere arrays should open up new possibilities for high-performance nanoscale optical sensors or photoelectric devices. PMID:26640125

  7. Monte Carlo simulations of the relative biological effectiveness for DNA double strand breaks from 300 MeV u−1 carbon-ion beams

    International Nuclear Information System (INIS)

    Monte Carlo simulations are used to calculate the relative biological effectiveness (RBE) of 300 MeV u−1 carbon-ion beams at different depths in a cylindrical water phantom of 10 cm radius and 30 cm long. RBE values for the induction of DNA double strand breaks (DSB), a biological endpoint closely related to cell inactivation, are estimated for monoenergetic and energy-modulated carbon ion beams. Individual contributions to the RBE from primary ions and secondary nuclear fragments are simulated separately. These simulations are based on a multi-scale modelling approach by first applying the FLUKA (version 2011.2.17) transport code to estimate the absorbed doses and fluence energy spectra, then using the MCDS (version 3.10A) damage code for DSB yields. The approach is efficient since it separates the non-stochastic dosimetry problem from the stochastic DNA damage problem. The MCDS code predicts the major trends of the DSB yields from detailed track structure simulations. It is found that, as depth is increasing, RBE values increase slowly from the entrance depth to the plateau region and change substantially in the Bragg peak region. RBE values reach their maxima at the distal edge of the Bragg peak. Beyond this edge, contributions to RBE are entirely from nuclear fragments. Maximum RBE values at the distal edges of the Bragg peak and the spread-out Bragg peak are, respectively, 3.0 and 2.8. The present approach has the flexibility to weight RBE contributions from different DSB classes, i.e. DSB0, DSB+ and DSB++. (paper)

  8. Detection of the linear carbon cluster C10: rotationally resolved diode-laser spectroscopy.

    Science.gov (United States)

    Giesen, T F; Berndt, U; Yamada, K M; Fuchs, G; Schieder, R; Winnewisser, G; Provencal, R A; Keutsch, F N; Van Orden, A; Saykally, R J

    2001-04-17

    Detected in interstellar space and as intermediates in soot formation, molecules of pure carbon in the form of linear chains or ring structures have interested researchers for several decades, who attempt to elucidate their physical properties and the processes govering their formation. A high-resolution infrared spectrometer housing a tunable diode laser and combined with an effective laser ablation source for the cluster production has been used to study the molecular properties of small carbon clusters; reported herein is the first gas-phase spectrum of linear C10.

  9. Optical alignment and characterization of the radial neutron beam duct number 4 of de RP-10 nuclear reactor

    International Nuclear Information System (INIS)

    We show the process of optical axis alignment of the neutrography device and the optical axis of the neutron beam from the radial duct number 4 of the RP-10 Nuclear Reactor, using optical methods, assisted by radiography, which facilitates the location of the optical axis of the neutron beam by the photographic recording of the space, allowing the alignment of the neutrography plate later. In the process, the location and orientation of the source depends on the placement of the fuel elements immersed inside the duct and between the core and the collimator in the Nuclear Reactor wall. This part of the process depends on the reactor operating personnel who calculate optimally the fuel burn and perform the analysis of the spatial distribution of radiation. The power measurement and the final adjustment of the optical axis of the neutron beam with the optical axis of the instrument are shown in this paper, which will make possible neutrography experiments, as well as neutron diffraction, neutron spectroscopy and neutron optics among others. (orig.)

  10. Cationic concentration effects on electron beam cured of carbon-epoxy composites

    International Nuclear Information System (INIS)

    Electron beam (e-beam) curing is a technology that offers advantages over the thermal curing process, that usually requires high temperature and are time-consuming. E-beam curing is faster and occurs at low temperatures that help reduce residual mechanical stresses in a thermoset composite. The aim of the present study is to analyze the effects of cationic initiator (diaryliodonium hexafluoroantimonate) ranged from 1 to 3 wt% in DGEBA (diglycidyl ether of bisphenol A) epoxy resin when cured by a 1.5 MeV electron beam. The specimens were cured to a total dose of 200.4 kGy for 40 min. Analyses by dynamic mechanical thermal analysis (DMTA) and differential scanning calorimetry (DSC) show that the e-beam irradiated samples with 2 wt% cationic initiator were 96% cured obtained a glass transition temperature (tan δ) of 167 deg. C. The same epoxy resin, thermally cured for 16 h with an anhydride hardener, reached a Tg (tan δ) of 136 deg. C. So, the irradiated sample had its Tg increased approximately 20% and the curing process was much less time consuming.

  11. Cationic concentration effects on electron beam cured of carbon-epoxy composites

    Energy Technology Data Exchange (ETDEWEB)

    Nishitsuji, D.A., E-mail: delmo_amari@yahoo.com.b [Brazilian Navy Technological Center, Sao Paulo (Brazil); Marinucci, G. [Brazilian Navy Technological Center, Sao Paulo (Brazil); Energetic and Nuclear Research Institute-IPEN-CNEN/SP, Av. Prof. Lineu Prestes, 2242-Cidade Universitaria, 05508-000 Sao Paulo/SP (Brazil); Evora, M.C. [Institute of Advanced Studies/CTA, Sao Jose dos Campos/SP (Brazil); Silva, L.G.A. [Energetic and Nuclear Research Institute-IPEN-CNEN/SP, Av. Prof. Lineu Prestes, 2242-Cidade Universitaria, 05508-000 Sao Paulo/SP (Brazil)

    2010-03-15

    Electron beam (e-beam) curing is a technology that offers advantages over the thermal curing process, that usually requires high temperature and are time-consuming. E-beam curing is faster and occurs at low temperatures that help reduce residual mechanical stresses in a thermoset composite. The aim of the present study is to analyze the effects of cationic initiator (diaryliodonium hexafluoroantimonate) ranged from 1 to 3 wt% in DGEBA (diglycidyl ether of bisphenol A) epoxy resin when cured by a 1.5 MeV electron beam. The specimens were cured to a total dose of 200.4 kGy for 40 min. Analyses by dynamic mechanical thermal analysis (DMTA) and differential scanning calorimetry (DSC) show that the e-beam irradiated samples with 2 wt% cationic initiator were 96% cured obtained a glass transition temperature (tan delta) of 167 deg. C. The same epoxy resin, thermally cured for 16 h with an anhydride hardener, reached a T{sub g} (tan delta) of 136 deg. C. So, the irradiated sample had its T{sub g} increased approximately 20% and the curing process was much less time consuming.

  12. TH-C-12A-10: Surface Dose Enhancement Using Novel Hybrid Electron and Photon Low-Z Therapy Beams: Monte Carlo Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Parsons, C; Parsons, D [Dept of Physics and Atmospheric Science, Dalhousie University, Halifax, Nova Scotia (Canada); Robar, J; Kelly, R [Dept of Physics and Atmospheric Science, Dalhousie University, Halifax, Nova Scotia (Canada); Dept of Radiation Oncology, Dalhousie University, Halifax, Nova Scotia (Canada); Nova Scotia Cancer Centre, Halifax, NS (Canada)

    2014-06-15

    Purpose: The introduction of the TrueBeam linac platform provides access to an in-air target assembly making it possible to apply novel treatments using multiple target designs. One such novel treatment uses multiple low-Z targets to enhance surface dose replacing the use of synthetic tissue equivalent material (bolus). This treatment technique will decrease the common dosimetric and set up errors prevalent in using physical treatment accessories like bolus. The groundwork for a novel treatment beam used to enhance surface dose to within 80-100% of the dose at dmax by utilizing low-Z (Carbon) targets of various percent CSDA range thickness operated at 2.5–4 MeV used in conjunction with a clinical 6 MV beam is presented herein. Methods: A standard Monte Carlo model of a Varian Clinac accelerator was developed to manufacturers specifications. Simulations were performed using Be, C, AL, and C, as potential low-Z targets, placed in the secondary target position. The results determined C to be the target material of choice. Simulations of 15, 30 and 60% CSDA range C beams were propagated through slab phantoms. The resulting PDDs were weighted and combined with a standard 6 MV treatment beam. Versions of the experimental targets were installed into a 2100C Clinac and the models were validated. Results: Carbon was shown to be the low-Z material of choice for this project. Using combinations of 15, 30, 60% CSDA beams operated at 2.5 and 4 MeV in combination with a standard 6 MV treatment beam the surface dose was shown to be enhanced to within 80–100% the dose at dmax. Conclusion: The modeled low-Z beams were successfully validated using machined versions of the targets. Water phantom measurements and slab phantom simulations show excellent correlation. Patient simulations are now underway to compare the use of bolus with the proposed novel beams. NSERC.

  13. Sci—Sat AM: Stereo — 04: Evaluation of VMAT interplay effect for lung SABR using TrueBeam 10XFFF beam

    Energy Technology Data Exchange (ETDEWEB)

    Huang, V; Thomas, SD [BC Cancer Agency, Fraser Valley Cancer Centre (Canada); Teke, T [BC Cancer Agency, Centre for the Southern Interior (Canada)

    2014-08-15

    During a VMAT treatment delivery, the interplay effect between the moving target and varying machine parameters result in dose distributions that are different from those initially planned. In this work, we investigate this effect for lung SABR by using 4D dose calculation derived from the Varian TrueBeam trajectory log file. The impact of treatment start phase is also evaluated. A QUASAR™ respiratory motion phantom was scanned with motion amplitudes of 0.4, 1, 2 and 3 cm with a 4 second period. MIP and the average dataset were generated from the 4DCT. A static CT was also acquired with the tumor in its centre position. Plans were optimized with 10X FFF beam until PTV and fictitious critical structures met the dose constraints. Ten temporally interleaved plans were constructed with the temporal machine parameter information from the trajectory log file. Ten plans were calculated with isocentre shifts to simulate respiratory motion and then summed. For each motion amplitude, three separate sum plans were created with various phase shifts (no phase shift, maximum inhalation and maximum exhalation) to assess the impact of treatment start phase. For all the phase shifts investigated, the DVH for PTV demonstrated good dose coverage. However, a careful review of slice by slice plan comparison indicates dose “holes” are observed within PTV. The PTV dose difference between various treatment start phases can be as high as 19%. This assumes all treatment fractions have identical treatment start phase. Our future work includes evaluation of interplay effect for various breathing periods.

  14. 10 Orders of Magnitude Current Measurement Digitisers for the CERN Beam Loss Systems

    CERN Document Server

    Vigano, W; Dehning, B; Kwiatkowski, M; Venturini, G G; Zamantzas, C

    2014-01-01

    A wide range current digitizer card is needed for the acquisition module of the beam loss monitoring systems in the CERN Injector Complex. The fully differential frequency converter allows measuring positive and negative input currents with a resolution of 31nA in an integration window of 2μs. Increasing the integration window, the dynamic range covers 2•1010 were the upper part of the range is converted by measuring directly the voltage drop on a resistor. The key elements of this design are the fully differential integrator and the switches operated by an FPGA. The circuit is designed to avoid any dead time in the acquisition and reliability and failsafe operational considerations are main design goals. The circuit will be discussed in detail and lab and field measurements will be shown.

  15. 10 orders of magnitude current measurement digitisers for the CERN beam loss systems

    Science.gov (United States)

    Viganò, W.; Alsdorf, M.; Dehning, B.; Kwiatkowski, M.; Venturini, G. G.; Zamantzas, C.

    2014-02-01

    A wide range current digitizer card is needed for the acquisition module of the beam loss monitoring systems in the CERN Injector Complex. The fully differential frequency converter allows measuring positive and negative input currents with a resolution of 31 nA in an integration window of 2 μs. Increasing the integration window, the dynamic range covers 21010 were the upper part of the range is converted by measuring directly the voltage drop on a resistor. The key elements of this design are the fully differential integrator and the switches operated by an FPGA. The circuit is designed to avoid any dead time in the acquisition and reliability and failsafe operational considerations are main design goals. The circuit will be discussed in detail and lab and field measurements will be shown.

  16. Management of the installation of a 10 MeV, 50 kW electron-beam irradiator

    International Nuclear Information System (INIS)

    An IMPELA-10/50 electron-beam irradiator has been installed by AECL Accelerators in Iotron Industries' service centre near Vancouver. Construction of the facility, installation of the accelerator and conveyor, and commissioning to the full rated power of 50 kW were completed in 12 months. Iotron began commercial irradiation immediately and the first continuous operation achieved 250 hours of production in 12 days. The engineering, production and project management organizations and activities to complete the on-schedule installation and commissioning are reviewed. (author). 3 refs., 2 tabs., 1 fig

  17. Chemical investigations of isotope separation on line target units for carbon and nitrogen beams

    CERN Document Server

    Franberg, H; Gäggeler, H W; Köster, U

    2006-01-01

    Radioactive ion beams (RIBs) are of significant interest in a number of applications. Isotope separation on line (ISOL) facilities provide RIB with high beam intensities and good beam quality. An atom that is produced within the ISOL target will first diffuse out from the target material. During the effusion towards the transfer line and into the ion source the many contacts with the surrounding surfaces may cause unacceptable delays in the transport and, hence, losses of the shorter-lived isotopes. We performed systematic chemical investigations of adsorption in a temperature and concentration regime relevant for ISOL targets and ion source units, with regard to CO/sub x/ and NOmaterials are potential construction materials for the above-mentioned areas. Off-line and on-line tests have been performed using a gas thermochromatography setup with radioactive tracers. The experiments were performed at the production of tracers for atmospheric chemistry (PROTRAC) facility at the Paul Schener Institute in Villigen...

  18. MODIFICATION OF CARBON STEEL BY LASER SURFACE MELTING: PART II: EFFECT OF LASER BEAM POWER ON MICROSTRUCTURAL FEATURES AND SURFACE HARDNESS

    OpenAIRE

    Hashem F. El-Labban; Abdelaziz, M.; Essam R.I. Mahmoud

    2013-01-01

    The surface hardness has an important effect on the wear resistance of different materials. The present study aims to improve the surface hardness of carbon steel through the application of laser surface melting with suitable conditions. The laser beam power and travelling speed are the main factors that affect the properties of the treated zone. In this study, three different conditions of laser beam power (1800, 1500 and 1200 W) at fixed travelling speed of 1000 mm min-1 were chosen to stud...

  19. Amorphous track modelling of luminescence detector efficiency in proton and carbon beams

    DEFF Research Database (Denmark)

    Greilich, Steffen; Grzanka, Leszek; Bassler, Niels;

    Introduction: The radioluminescence (RL) and optically stimulated luminescence (OSL) response of Al2O3:C crystals attached to optical fibres can be used for active and passive in-vivo dosimetry in radiotherapy treatments and clinical imaging techniques. Their use in particle beams, however, can b...

  20. A Study of Charged Current Single Charged Pion Productions on Carbon in a Few-GeV Neutrino Beam

    Energy Technology Data Exchange (ETDEWEB)

    Hiraide, Katsuki; /Kyoto U.

    2009-01-01

    Understanding single charged pion production via neutrino-nucleus charged current interaction in the neutrino energy region of a few GeV is essential for future neutrino oscillation experiments since this process is a dominant background for {nu}{sub {mu}} {yields} {nu}{sub x} oscillation measurements. There are two contributions to this process: single pion production via baryonic resonance ({nu}{sub {mu}}N {yields} {mu}{sup -} N{pi}{sup +}) and coherent pion production interacting with the entire nucleus ({nu}{sub {mu}}A {yields} {mu}{sup -} A{pi}{sup +}), where N is nucleon in the nucleus and A is the nucleus. The purpose of the study presented in this thesis is a precise measurement of charged current single charged pion productions, resonant and coherent pion productions, with a good final state separation in the neutrino energy region of a few GeV. In this thesis, we focus on the study of charged current coherent pion production from muon neutrinos scattering on carbon, {nu}{sub {mu}} {sup 12}C {yields} {mu}{sup -12}C{pi}{sup +}, in the SciBooNE experiment. This is motivated by the fact that without measuring this component first, the precise determination of resonant pion production cross section can not be achieved since the contribution of coherent pion production in the region of small muon scattering angle is not small. Furthermore, the coherent process is particularly interesting because it is deeply rooted in fundamental physics via Adler's partially conserved axial-vector current theorem. We took data from June 2007 until August 2008, in both the neutrino and antineutrino beam. In total, 2.52 x 10{sup 20} protons on target were collected. We have performed a search for charged current coherent pion production by using SciBooNE's full neutrino data set, corresponding to 0.99 x 10{sup 20} protons on target. No evidence for coherent pion production is observed. We set 90% confidence level upper limits on the cross section ratio of charged

  1. A Study of Charged Current Single Charged Pion Productions on Carbon in a Few-GeV Neutrino Beam

    Energy Technology Data Exchange (ETDEWEB)

    Hiraide, Katsuki [Kyoto Univ. (Japan)

    2009-01-01

    Understanding single charged pion production via neutrino-nucleus charged current interaction in the neutrino energy region of a few GeV is essential for future neutrino oscillation experiments since this process is a dominant background for vμ → vx oscillation measurements. There are two contributions to this process: single pion production via baryonic resonance (vμN → μ-+) and coherent pion production interacting with the entire nucleus (vμA → μ-+), where N is nucleon in the nucleus and A is the nucleus. The purpose of the study presented in this thesis is a precise measurement of charged current single charged pion productions, resonant and coherent pion productions, with a good final state separation in the neutrino energy region of a few GeV. In this thesis, we focus on the study of charged current coherent pion production from muon neutrinos scattering on carbon, vμ 12C → μ-12+, in the SciBooNE experiment. This is motivated by the fact that without measuring this component first, the precise determination of resonant pion production cross section can not be achieved since the contribution of coherent pion production in the region of small muon scattering angle is not small. Furthermore, the coherent process is particularly interesting because it is deeply rooted in fundamental physics via Adler's partially conserved axial-vector current theorem. We took data from June 2007 until August 2008, in both the neutrino and antineutrino beam. In total, 2.52 x 1020 protons on target were collected. We have performed a search for charged current coherent pion production by using SciBooNE's full neutrino data set, corresponding to 0.99 x 1020 protons on target. No evidence for coherent pion production is observed. We set 90% confidence level upper limits on the cross section ratio

  2. Optical diagnostic suite (schlieren, interferometry, and grid image refractometry) on OMEGA EP using a 10-ps, 263-nm probe beam

    Energy Technology Data Exchange (ETDEWEB)

    Froula, D. H.; Boni, R.; Bedzyk, M.; Craxton, R. S.; Ehrne, F.; Ivancic, S.; Jungquist, R.; Shoup, M. J.; Theobald, W.; Weiner, D. [Laboratory for Laser Energetics, University of Rochester, 250 E. River Rd., Rochester, New York 14616 (United States); Kugland, N. L.; Rushford, M. C. [Lawrence Livermore National Laboratory, University of California, P. O. Box 808, Livermore, California 94551 (United States)

    2012-10-15

    A 10-ps, 263-nm (4{omega}) laser is being built to probe plasmas produced on the OMEGA EP [J. H. Kelly, L. J. Waxer, V. Bagnoud, I. A. Begishev, J. Bromage, B. E. Kruschwitz, T. E. Kessler, S. J. Loucks, D. N. Maywar, R. L. McCrory et al., J. Phys. IV France 133, 75-80 (2006)]. A suite of optical diagnostics (schlieren, interferometry, and grid image refractometry) has been designed to diagnose and characterize a wide variety of plasmas. Light scattered by the probe beam is collected by an f/4 catadioptric telescope and a transport system is designed to image with a near-diffraction-limited resolution ({approx}1 -{mu}m full width at half maximum) over a 5-mm field of view to a diagnostic table. The transport system provides a contrast greater than 1 : 10{sup 4} with respect to all wavelengths outside of the 263 {+-} 2 nm measurement range.

  3. Atomistic description of electron beam damage in nitrogen-doped graphene and single-walled carbon nanotubes.

    Science.gov (United States)

    Susi, Toma; Kotakoski, Jani; Arenal, Raul; Kurasch, Simon; Jiang, Hua; Skakalova, Viera; Stephan, Odile; Krasheninnikov, Arkady V; Kauppinen, Esko I; Kaiser, Ute; Meyer, Jannik C

    2012-10-23

    By combining ab initio simulations with state-of-the-art electron microscopy and electron energy loss spectroscopy, we study the mechanism of electron beam damage in nitrogen-doped graphene and carbon nanotubes. Our results show that the incorporation of nitrogen atoms results in noticeable knock-on damage in these structures already at an acceleration voltage of 80 kV, at which essentially no damage is created in pristine structures at corresponding doses. Contrary to an early estimate predicting rapid destruction via sputtering of the nitrogen atoms, in the case of substitutional doping, damage is initiated by displacement of carbon atoms neighboring the nitrogen dopant, leading to the conversion of substitutional dopant sites into pyridinic ones. Although such events are relatively rare at 80 kV, they become significant at higher voltages typically used in electron energy loss spectroscopy studies. Correspondingly, we measured an energy loss spectrum time series at 100 kV that provides direct evidence for such conversions in nitrogen-doped single-walled carbon nanotubes, in excellent agreement with our theoretical prediction. Besides providing an improved understanding of the irradiation stability of these structures, we show that structural changes cannot be neglected in their characterization employing high-energy electrons.

  4. Using a carbon beam as a probe to extract the sensitive volume thickness; Utilisation d'un faisceau de carbon pour extraire le volume sensible

    Energy Technology Data Exchange (ETDEWEB)

    Inguimbert, C.; Duzellier, S. [Office National d' Etudes et de Recherches Aerospatiales (ONERA/DESP), 31 - Toulouse (France); Ecoffet, R. [Centre National d' Etudes Spatiales (CNES), 31 - Toulouse (France)

    1999-07-01

    Most of the models of proton SEUs predictions use the sensitive volume concept. The sensitive region is modeled by a parallelepiped with length l, width w and thickness d, buried at depth h. We propose a new method to extract the sensitive thickness d. The idea is to use low energy, low range ion in order to probe the component to measure the sensitive volume. The thickness d is obtained by de-convoluting the heavy ion upset cross-section curve with the LET (linear energy transfer) curve, both curves being considered as functions of the range of the incident ion. This method has been tested using a beam of carbon ions and the calculated thickness is closed to the theoretical expected value. The deconvolution method which couples together a sensitive thickness d and a charge collection efficiency {alpha} improves the sensitive volume concept.

  5. Chemical Investigations of ISOL target units for carbon and nitrogen beams

    CERN Document Server

    Franberg, H; Gäggeler, H W; Köster, U

    2006-01-01

    Radioactive Ion Beams (RIB) are of significant interest in a number of applications. ISOL (Isotope Separation On Line) facilities provide RIB with high beam intensities and good beam quality. An atom that is produced within the ISOL target will first diffuse out from the target material. During the effusion towards the transfer line and into the ion source the many contacts with the surrounding surfaces may cause unacceptable delays in the transport and, hence, losses of the shorter-lived isotopes. We performed systematic chemical investigations of adsorption in a temperature and concentration regime relevant for ISOL targets and ion source units, with regard to COx and NOx on Al2O3 and SiO2. These materials are potential construction materials for the above mentioned areas. Off-line and on-line tests have been performed using a gas thermo-chromatography set-up with radioactive tracers. The experiments were performed at the PROTRAC facility at Paul Scherrer Institute in Villigen, Switzerland.

  6. Rapid phase-correlated rescanning irradiation improves treatment time in carbon-ion scanning beam treatment under irregular breathing

    Science.gov (United States)

    Mori, Shinichiro; Furukawa, Takuji

    2016-05-01

    To shorten treatment time in pencil beam scanning irradiation, we developed rapid phase-controlled rescanning (rPCR), which irradiates two or more isoenergy layers in a single gating window. Here, we evaluated carbon-ion beam dose distribution with rapid and conventional PCR (cPCR). 4 dimensional computed tomography (4DCT) imaging was performed on 12 subjects with lung or liver tumors. To compensate for intrafractional range variation, the field-specific target volume (FTV) was calculated using 4DCT within the gating window (T20–T80). We applied an amplitude-based gating strategy, in which the beam is on when the tumor is within the gating window defined by treatment planning. Dose distributions were calculated for layered phase-controlled rescanning under an irregular respiratory pattern, although a single 4DCT data set was used. The number of rescannings was eight times. The prescribed doses were 48 Gy(RBE)/1 fr (where RBE is relative biological effectiveness) delivered via four beam ports to the FTV for the lung cases and 45 Gy(RBE)/2 fr delivered via two beam ports to the FTV for the liver cases. In the liver cases, the accumulated dose distributions showed an increased magnitude of hot/cold spots with rPCR compared with cPCR. The results of the dose assessment metrics for the cPCR and rPCR were very similar. The D 95, D max, and D min values (cPCR/rPCR) averaged over all the patients were 96.3  ±  0.9%/96.0  ±  1.2%, 107.3  ±  3.6%/107.1  ±  2.9%, and 88.8  ±  3.2%/88.1  ±  3.1%, respectively. The treatment times in cPCR and rPCR were 110.7 s and 53.5 s, respectively. rPCR preserved dose conformation under irregular respiratory motion and reduced the total treatment time compared with cPCR.

  7. Inferring phytoplankton carbon and eco-physiological rates from diel cycles of spectral particulate beam-attenuation coefficient

    Directory of Open Access Journals (Sweden)

    G. Dall'Olmo

    2011-03-01

    Full Text Available The diurnal fluctuations in solar irradiance impose a fundamental frequency on ocean biogeochemistry. Observations of the ocean carbon cycle at these frequencies are rare, but could be considerably expanded by measuring and interpreting the inherent optical properties. A method is presented to analyze diel cycles in particulate beam-attenuation coefficient (cp measured at multiple wavelengths. The method is based on fitting observations with a size-structured population and optical model to infer the particle size distribution and physiologically relevant parameters of the cells responsible for the measured diel cycle in cp. Results show that the information related to size and contained in the spectral data can be exploited to independently estimate growth and loss rates during the day and night. In addition, the model can characterize the population of particles affecting the cp diel variability. Application of this method to spectral cp measured at a station in the oligotrophic Mediterranean Sea suggests that most of the observed variations in cp can be ascribed to a synchronized population of cells with an equivalent spherical diameter between 1 and 4 μm. The inferred carbon biomass of these cells was about 8–13 mg m−3 and accounted for approximately 20% of the total particulate organic carbon. If successfully validated and implemented on autonomous platforms, this method could improve our understanding of the ocean carbon cycle.

  8. Selective radiography of 10B distribution in organs using cold and thermal neutron beams

    International Nuclear Information System (INIS)

    The investigation of boron biodistribution by neutron induced autoradiography was performed using a CR-39 etched track detector. Calibration samples, made of boronated chicken liver, and freeze-dried mouse tissue samples were irradiated both with thermal and cold neutrons. Digital images were made on the basis of track densities, with the selection of tracks due to 10B(n, α) 7Li reaction. A comparison of results obtained both with thermal and cold neutrons demonstrated that it is possible to obtain equivalent results with both neutron sources, although the background noise due to recoil protons from the fast neutrons of the thermal neutron source is 15% higher than that of the cold neutron source. 10B concentrations in the range of 0.5 ppm to 150 ppm were determined, with a standard deviation of 13% and 8% for the mouse tissue samples and calibration samples, respectively. (author)

  9. Imperfection Sensitivity of Nonlinear Vibration of Curved Single-Walled Carbon Nanotubes Based on Nonlocal Timoshenko Beam Theory

    Directory of Open Access Journals (Sweden)

    Iman Eshraghi

    2016-09-01

    Full Text Available Imperfection sensitivity of large amplitude vibration of curved single-walled carbon nanotubes (SWCNTs is considered in this study. The SWCNT is modeled as a Timoshenko nano-beam and its curved shape is included as an initial geometric imperfection term in the displacement field. Geometric nonlinearities of von Kármán type and nonlocal elasticity theory of Eringen are employed to derive governing equations of motion. Spatial discretization of governing equations and associated boundary conditions is performed using differential quadrature (DQ method and the corresponding nonlinear eigenvalue problem is iteratively solved. Effects of amplitude and location of the geometric imperfection, and the nonlocal small-scale parameter on the nonlinear frequency for various boundary conditions are investigated. The results show that the geometric imperfection and non-locality play a significant role in the nonlinear vibration characteristics of curved SWCNTs.

  10. Preparation of diamond-like carbon and boron nitirde films by high-intensity pulsed ion beam deposition

    Energy Technology Data Exchange (ETDEWEB)

    Rej, D.J.; Davis, H.A. [Los Alamos National Lab., NM (United States); Remnev, G.E. [Tomsk Polytechnic Univ., Tomsk (Russian Federation). Nuclear Physics Institute.] [and others

    1995-05-01

    Intense ion beams (300-keV C{sup +}, O{sup +}, and H{sup +}, 20--30 kA, 50 to 400-ns pulsewidth, up to 0.3-Hz repetition rate) were used to prepare diamond-like carbon (DLC) and boron nitride (BN) films. Deposition rates of up to 25{plus_minus}5 nm/pulse were obtained with instantaneous rates exceeding 1 mm/s. Most films were uniform, light brown, translucent, and nonporous with some micron-size particulates. Raman and parallel electron energy loss spectroscopy indicated the presence of DLC. The films possessed favorable electron field-emission characteristics desirable for cold-cathode displays. Transmission electron microscopy (TEM) and transmission electron diffraction (TED) revealed that the C films contained diamond crystals with 25 to 125-nm grain size. BN films were composed of hexagonal, cubic and wurtzite phases.

  11. Radiosensitivity of cancer cells against carbon-ion beams in an aspect of the p53 gene status

    International Nuclear Information System (INIS)

    We can easily understand that radiation sensitivities of cancer cells are dependent on the status of cancer-related genes. It is important to clarify which genes affect radiation sensitivity and reflect the effectiveness of radiation therapy for cancer cells. We have studied about the function of a tumor suppressor gene of p53, because p53 controls apoptosis, cell cycle and DNA repair from an aspect of important roles in cell fate. By analysis of function of p53 gene, therefore, we aim to predict the therapeutic effectiveness and to select the modalities of cancer therapies such as radiotherapy, chemotherapy and hyperthermia. As a final goal, we want to accept the most effective therapy, namely tailor-made cancer therapy, for each patient. Here, we introduce that carbon-beam therapy induced the expression of p53-independent apoptosis-related genes and NO radicals in mutated p53 cancer cells. (author)

  12. The use of multi-gap resistive plate chambers for in-beam PET in proton and carbon ion therapy

    CERN Document Server

    Watts, David; Sauli, Fabio; Amaldi, Ugo

    2013-01-01

    On-line verification of the delivered dose during proton and carbon ion radiotherapy is currently a very desirable goal for quality assurance of hadron therapy treatment plans. In-beam positron emission tomography (ibPET), which can provide an image of the β+ activity induced in the patient during irradiation, which in turn is correlated to the range of the ion beam, is one of the modalities for achieving this goal. Application to hadron therapy requires that the scanner geometry be modified from that which is used in nuclear medicine. In particular, PET detectors that allow a sub-nanosecond time-of-flight (TOF) registration of the collinear photons have been proposed. Inclusion of the TOF information in PET data leads to more effective PET sensitivity. Considering the challenges inherent in the ibPET technique, namely limited β+ activity and the effect of biological washout due to blood flow, TOF-PET technologies are very attractive. In this context, the TERA Foundation is investigating the use of resistiv...

  13. Radiosensitivity and Induction of Apoptosis by High LET Carbon Ion Beam and Low LET Gamma Radiation: A Comparative Study

    Directory of Open Access Journals (Sweden)

    Atanu Ghorai

    2014-01-01

    Full Text Available Cancer treatment with high LET heavy ion beam, especially, carbon ion beam (12C, is becoming very popular over conventional radiotherapy like low LET gamma or X-ray. Combination of Poly(ADP-ribose polymerase (PARP inhibitor with xenotoxic drugs or conventional radiation (gamma or X-ray is the newer approach for cancer therapy. The aim of our study was to compare the radiosensitivity and induction of apoptosis by high LET 12C and low LET gamma radiation in HeLa and PARP-1 knocked down cells. We did comet assay to detect DNA breaks, clonogenic survival assay, and cell cycle analysis to measure recovery after DNA damage. We measured apoptotic parameters like nuclear fragmentation and caspase-3 activation. DNA damage, cell killing, and induction of apoptosis were significantly higher for 12C than gamma radiation in HeLa. Cell killing and apoptosis were further elevated upon knocking down of PARP-1. Both 12C and gamma induced G2/M arrest although the 12C had greater effect. Unlike the gamma, 12C irradiation affects DNA replication as detected by S-phase delay in cell cycle analysis. So, we conclude that high LET 12C has greater potential over low LET gamma radiation in killing cells and radiosensitization upon PARP-1 inhibition was several folds greater for 12C than gamma.

  14. Effects of E-Beam Irradiation on the Chemical, Physical, and Electrochemical Properties of Activated Carbons for Electric Double-Layer Capacitors

    Directory of Open Access Journals (Sweden)

    Min-Jung Jung

    2015-01-01

    Full Text Available Activated carbons (ACs were modified via e-beam irradiation at various doses for use as an electrode material in electric double-layer capacitors (EDLCs. The chemical compositions of the AC surfaces were largely unchanged by the e-beam irradiation. The ACs treated with the e-beam at radiation doses of 200 kGy exhibited higher nanocrystallinity than the untreated ACs. The specific surface areas and pore volumes of the e-beam irradiated ACs were also higher than those of the untreated ACs. These results were attributed to the transformation and degradation of the nanocrystallinity of the AC surfaces due to the e-beam irradiation. The specific capacitance of the ACs treated with the e-beam at radiation doses of 200 kGy increased by 24% compared with the untreated ACs, and the charge transfer resistance of the ACs was decreased by the e-beam irradiation. The enhancement of the electrochemical properties of the e-beam irradiated ACs can be attributed to an increase in their specific surface area and surface crystallinity.

  15. Electrostatic probe diagnostics on the LBL 10 ampere neutral beam ion source

    Energy Technology Data Exchange (ETDEWEB)

    Schoenberg, K.F.

    1978-08-01

    The experimental results of electrostatic probe measurements on the LBL 10 ampere ion source are presented. Data is obtained via a pulsed acquisition system which digitally records a probe characteristic and its first and second derivatives. The latter are shown to be proportional to the projected electron energy distribution function, and the isotropic electron energy distribution function, respectively. System performance for distribution function measurement is compared to the established technique of harmonic analysis. A complete analysis of the data acquisition system and its experimental accuracy is presented.

  16. Carbon species in PM10 particle fraction at different monitoring sites.

    Science.gov (United States)

    Godec, Ranka; Jakovljević, Ivana; Šega, Krešimir; Čačković, Mirjana; Bešlić, Ivan; Davila, Silvije; Pehnec, Gordana

    2016-09-01

    The aim of this study was to determine and compare the levels of elemental carbon (EC), organic carbon (OC) and polycyclic aromatic hydrocarbons (PAHs) mass concentrations in PM10 particles (particles with aerodynamic diameter less than 10 μm) between seasons (winter and summer) and at different monitoring sites (urban background and rural industrial). Daily samples of airborne particles were collected on pre-fired quartz fibre filters. PM10 mass concentrations were determined gravimetrically. Samples were analysed for OC and EC with the thermal/optical transmittance method (TOT) and for PAHs by high-performance liquid chromatography (HPLC) with a fluorescence detector. Measurements showed seasonal and spatial variations of mass concentrations for carbon species and for all of the measured PAHs (Flu, Pyr, Chry, BaA, BbF, BaP, BkF, BghiP and IP) in PM10 at the urban site and rural monitoring site described here. Diagnostic PAH ratios (Flu/(Flu + Pyr), BaA/(BaA + Cry), IP/(IP + BghiP), BaP/BghiP, IP/BghiP and BaP/(BaP + Chry)) make it possible to assess the sources of pollution, and these showed that diesel vehicles accounted for most pollution at the rural-industrial (RI) site in the summer, whereas coal and wood combustion were the causes of winter pollution. This difference between winter and summer PAH ratios were more expressed at the RI site than at the UB site because at the UB site the predominant heating fuel was gas. The OC/EC ratio yielded the same conclusion. Factor analysis showed that EC and OC originated from traffic at both sites, PAHs with 5 or more benzene rings originated from wood pellets industry or biomass burning, while Pyr and Flu originated from diesel combustion or as a consequence of different atmospheric behaviour - evaporation and participation in oxidation and photo oxidation processes.

  17. Experimental study of proton beam halo in mismatched beams

    International Nuclear Information System (INIS)

    We report measurements of transverse beam-halo formation in mismatched proton beams in a 52-quadrupole FODO-transport channel following the 6.7 MeV RFQ at the Low-Energy Demonstration Accelerator (LEDA) at Los Alamos. Beam profiles in both transverse planes were measured using a new diagnostic device that consists of a movable carbon filament for measurement of the beam core, and scraper plates for measurement of the outer part of the distributions. The initial results indicate a surprisingly strong growth rate of the rms emittance even for the modest space-charge tune depressions of the experiment. Our results are consistent with the complete transfer of free energy of the mismatched beams into emittance growth within 10 envelope oscillations for both the breathing and the quadrupole modes.

  18. Design and characterization of a multi-beam micro-CT scanner based on carbon nanotube field emission x-ray technology

    Science.gov (United States)

    Peng, Rui

    In this dissertation, I will present the results for my Ph.D. research for the past five years. My project mainly focuses on advanced imaging applications with a multi-beam x-ray source array based on carbon nanotube field emission technology. In the past few years, research in carbon nanotubes gradually changed from the raw material science to its application. Field emission x-ray application is one of the hottest research areas for carbon nanotube. Compared to traditional thermionic x-ray sources, the carbon nanotube field emission x-ray source has some natural advantages over traditional thermionic x-ray sources such as instantaneous x-ray generation, programmability and miniaturization. For the past few years, the research and development of carbon nanotube field emission x-ray has shifted from single x-ray beam applications to spatially distributed multi-beam x-ray sources. Previously in Zhou group, we have already built a gated micro-CT system with single beam micro-focus x-ray tube for higher spatial and temporal resolution as required in live animal imaging and a multi-beam tomosynthesis system targeting for faster and more stable breast imaging. Now my project mainly focused on the design, characterization and optimization of a multi-beam micro-CT imaging system. With the increase of gantry rotation speed approaching the mechanical limit, it is getting more and more difficult to further speed up the CT scanning. My new system promises a potential solution for the problem, and it serves as a great test platform for truly stationary micro-CT geometry. The potential capabilities it showed during the characterization and imaging measurements was promising. The dissertation is composed of five chapters. In Chapter 1, I will generally review the physics principles of x-ray generation and interaction with matter. Then the discovery of carbon nanotube and its great potential to serve as an excellent field emission electron source will be introduced in the second

  19. Measurement of neutral current neutral pion production on Carbon in a Few-GeV Neutrino Beam

    OpenAIRE

    Kurimoto, Y

    2009-01-01

    The SciBooNE Collaboration has measured neutral current neutral pion production by the muon neutrino beam at a polystyrene target (C8H8). We obtained (7.7+- 0.5(stat.)+0.4-0.5 (sys.)) x 10^-2 as cross section ratio of the neutral current neutral pion production to total charged current cross section at the mean neutrino energy of 1.16 GeV. This result is consistent with the Monte Carlo prediction based on the Rein-Sehgal model

  20. Single-walled carbon nanotubes and nanocrystalline graphene reduce beam-induced movements in high-resolution electron cryo-microscopy of ice-embedded biological samples

    CERN Document Server

    Rhinow, Daniel; Turchanin, Andrey; Gölzhäuser, Armin; Kühlbrandt, Werner; 10.1063/1.3645010

    2011-01-01

    For single particle electron cryo-microscopy (cryoEM), contrast loss due to beam-induced charging and specimen movement is a serious problem, as the thin films of vitreous ice spanning the holes of a holey carbon film are particularly susceptible to beam-induced movement. We demonstrate that the problem is at least partially solved by carbon nanotechnology. Doping ice-embedded samples with single-walled carbon nanotubes (SWNT) in aqueous suspension or adding nanocrystalline graphene supports, obtained by thermal conversion of cross-linked self-assembled biphenyl precursors, significantly reduces contrast loss in high-resolution cryoEM due to the excellent electrical and mechanical properties of SWNTs and graphene.

  1. Search for Charged Current Coherent Pion Production on Carbon in a Few-GeV Neutrino Beam

    Energy Technology Data Exchange (ETDEWEB)

    Hiraide, K.; /Kyoto U.; Alcaraz-Aunion, J.L.; /Barcelona, IFAE; Brice, S.J.; /Fermilab; Bugel, Leonard G.; /MIT; Catala-Perez, J.; /Valencia U.; Cheng, G.; /Columbia U.; Conrad, J.M.; /MIT; Djurcic, Zelimir; /Columbia U.; Dore, U.; /Banca di Roma /Frascati; Finley, David A.; /Fermilab; Franke, A.J.; /Columbia U. /Banca di Roma /Frascati

    2008-11-01

    The SciBooNE Collaboration has performed a search for charged current coherent pion production from muon neutrinos scattering on carbon, nu{sub {mu}}{sup 12}C- {yields} {mu}{sup 12}Cpi{sup +}, with two distinct data samples. No evidence for coherent pion production is observed. We set 90% confidence level upper limits on the cross section ratio of charged current coherent pion production to the total charged current cross section at 0.67 x 10{sup -2} at mean neutrino energy 1.1 GeV and 1.36 x 10{sup -2} at mean neutrino energy 2.2 GeV.

  2. Induction of apoptosis in murione spleen lymphocytes using carbon ion beam

    International Nuclear Information System (INIS)

    To assess the capacity of heavy ions to induce apoptosis in lymphocytes, mice have been irradiated with accelerated carbon ions (95 MeV/nucleon) at doses ranging from 0.1 to 4 Gy. Their spleens were removed 24 h later and gently dissociated to prepare a single cell suspension. Mononuclear cells were then maintained in culture at 37oC, and the occurrence of apoptosis in these cells was analysed 24 h later. Lymphocytes were also irradiated in vitro, in the presence of Ac-DEVD-CHO, a potent caspase-3 and -7 inhibitor. Results from three experiments performed at the Grand Accelerateur National d'Ions Lourds (GANIL, Caen, France) are reported here. They indicate that carbon ions induce a marked, dose-dependent, reduction of the spleen weight and cellularity. However, in sharp contrast with spleen cells prepared from X-ray irradiated mice, only a slight increase of apoptosis is evidenced in cultured lymphocytes from mice irradiated with heavy ions. The significance of such results is discussed. So far, few data exist concerning the biological effects of heavy ions, in particular their capacity to induce apoptosis in lymphocytes; the present study provides useful clues for further investigations. (author)

  3. Effects of a 2-step culture with cytokine combinations on megakaryocytopoiesis and thrombopoiesis from carbon-ion beam-irradiated human hematopoietic stem/progenitor cells

    International Nuclear Information System (INIS)

    To evaluate whether the continuous treatment of two cytokine combinations is effective in megakaryocytopoiesis and thrombopoiesis in hematopoietic stem/progenitor cells exposed to heavy ion beams, the effects of a 2-step culture by a combination of recombinant human interleukin-3 (IL-3)+stem cell factor (SCF)+thrombopoietin (TPO), which just slightly protected against carbon-ion beam-induced damages, and a combination of IL-3+TPO, which selectively stimulated the differentiation of the hematopoietic stem/progenitor cells to megakaryocytes and platelets, were examined. CD34+-hematopoietic stem/progenitor cells isolated from the human placental and umbilical cord blood were exposed to carbon-ion beams (linear energy transfer (LET)=50 keV/μm) at 2 Gy. These cells were cultured under three cytokine conditions. The number of megakaryocytes, platelets and hematopoietic progenitors were assessed using a flow cytometer and a clonogenic assay at 14 and 21 days after irradiation, respectively. However, the efficacy of each 2-step culture was equal or lower than that of using the IL-3+SCF+TPO combination alone and the 2-step culture could not induce megakaryocytes and platelets from hematopoietic stem/progenitor cells exposed to high LET-radiation such as carbon-ion beams. Therefore, additional cytokines and/or hematopoietic promoting compounds might be required to overcome damage to hematopoietic cells by high LET radiation. (author)

  4. Construction of electron beam machine 350 keV/10 mA for multipurpose application of thin sample at P3TM-BATAN

    International Nuclear Information System (INIS)

    Research and development starting in 1984 of electron beam technology in Indonesia is first briefly presented. BATAN assigned to the Yogyakarta Nuclear Center the project of constructing an electron beam machine of 350 keV/10 mA for multipurpose applications especially for thin samples for duration of five years. The main objective of the project was the young scientists training and demonstration purposes in operation and maintenance of the machine. The engineers have learned through experience of the low energy ion accelerator (150 kV) many techniques to construct the system component such as E-gun, high voltage, vacuum, beam optics, scanning horn and window, beam stopper, and conveyer as well as the embedded control system. Because of the window cooling system, the uses of the machine are limited for irradiating a thin sample of plastics, hydrogel, powder, or liquid. Future plans for modification of the machine are stated. (S. Ohno)

  5. The use of multi-gap resistive plate chambers for in-beam PET in proton and carbon ion therapy

    Science.gov (United States)

    Watts, David; Borghi, Giacomo; Sauli, Fabio; Amaldi, Ugo

    2013-01-01

    On-line verification of the delivered dose during proton and carbon ion radiotherapy is currently a very desirable goal for quality assurance of hadron therapy treatment plans. In-beam positron emission tomography (ibPET), which can provide an image of the β+ activity induced in the patient during irradiation, which in turn is correlated to the range of the ion beam, is one of the modalities for achieving this goal. Application to hadron therapy requires that the scanner geometry be modified from that which is used in nuclear medicine. In particular, PET detectors that allow a sub-nanosecond time-of-flight (TOF) registration of the collinear photons have been proposed. Inclusion of the TOF information in PET data leads to more effective PET sensitivity. Considering the challenges inherent in the ibPET technique, namely limited β+ activity and the effect of biological washout due to blood flow, TOF-PET technologies are very attractive. In this context, the TERA Foundation is investigating the use of resistive plate chambers (RPC) for an ibPET application because of their excellent timing properties and low cost. In this paper we present a novel compact multi-gap RPC (MRPC) module design and construction method, which considering the large number of modules that would be needed to practically implement a high-sensitivity RPC-PET scanner, could be advantageous. Moreover, we give an overview of the efficiency and timing measurements that have been obtained in the laboratory using such single-gap and multi-gap RPC modules. PMID:23824118

  6. Electron-beam induced diamond-like-carbon passivation of plasmonic devices

    Science.gov (United States)

    Balaur, Eugeniu; Sadatnajafi, Catherine; Langley, Daniel; Lin, Jiao; Kou, Shan Shan; Abbey, Brian

    2015-12-01

    Engineered materials with feature sizes on the order of a few nanometres offer the potential for producing metamaterials with properties which may differ significantly from their bulk counterpart. Here we describe the production of plasmonic colour filters using periodic arrays of nanoscale cross shaped apertures fabricated in optically opaque silver films. Due to its relatively low loss in the visible and near infrared range, silver is a popular choice for plasmonic devices, however it is also unstable in wet or even ambient conditions. Here we show that ultra-thin layers of Diamond-Like Carbon (DLC) can be used to prevent degradation due to oxidative stress, ageing and corrosion. We demonstrate that DLC effectively protects the sub-micron features which make up the plasmonic colour filter under both atmospheric conditions and accelerated aging using iodine gas. Through a systematic study we confirm that the nanometre thick DLC layers have no effect on the device functionality or performance.

  7. The EGFR mutation status affects the relative biological effectiveness of carbon-ion beams in non-small cell lung carcinoma cells.

    Science.gov (United States)

    Amornwichet, Napapat; Oike, Takahiro; Shibata, Atsushi; Nirodi, Chaitanya S; Ogiwara, Hideaki; Makino, Haruhiko; Kimura, Yuka; Hirota, Yuka; Isono, Mayu; Yoshida, Yukari; Ohno, Tatsuya; Kohno, Takashi; Nakano, Takashi

    2015-06-11

    Carbon-ion radiotherapy (CIRT) holds promise to treat inoperable locally-advanced non-small cell lung carcinoma (NSCLC), a disease poorly controlled by standard chemoradiotherapy using X-rays. Since CIRT is an extremely limited medical resource, selection of NSCLC patients likely to benefit from it is important; however, biological predictors of response to CIRT are ill-defined. The present study investigated the association between the mutational status of EGFR and KRAS, driver genes frequently mutated in NSCLC, and the relative biological effectiveness (RBE) of carbon-ion beams over X-rays. The assessment of 15 NSCLC lines of different EGFR/KRAS mutational status and that of isogenic NSCLC lines expressing wild-type or mutant EGFR revealed that EGFR-mutant NSCLC cells, but not KRAS-mutant cells, show low RBE. This was attributable to (i) the high X-ray sensitivity of EGFR-mutant cells, since EGFR mutation is associated with a defect in non-homologous end joining, a major pathway for DNA double-strand break (DSB) repair, and (ii) the strong cell-killing effect of carbon-ion beams due to poor repair of carbon-ion beam-induced DSBs regardless of EGFR mutation status. These data highlight the potential of EGFR mutation status as a predictor of response to CIRT, i.e., CIRT may show a high therapeutic index in EGFR mutation-negative NSCLC.

  8. Hypofractionated carbon ion therapy delivered with scanned ion beams for patients with hepatocellular carcinoma – feasibility and clinical response

    International Nuclear Information System (INIS)

    Photon-based radiation therapy does currently not play a major role as local ablative treatment for hepatocellular carcinoma (HCC). Carbon ions offer distinct physical and biological advantages. Due to their inverted dose profile and the high local dose deposition within the Bragg peak, precise dose application and sparing of normal tissue is possible. Furthermore, carbon ions have an increased relative biological effectiveness (RBE) compared to photons. A total of six patients with one or more HCC-lesions were treated with carbon ions delivered by the raster-scanning technique according to our clinical trial protocol. Diagnosis of HCC was confirmed by histology or two different imaging modalities (CT and MRI) according to the AASLD-guidelines. Applied fractionation scheme was 4 × 10 Gy(RBE). Correct dose application was controlled by in-vivo PET measurement of β + −activity in the irradiated tissue shortly after treatment. Patients were observed for a median time period of 11.0 months (range, 3.4 – 12.7 months). Imaging studies showed a partial response in 4/7 lesions and a stable disease in 3/7 lesions in follow-up CT- and MRI scans. Local control was 100%. One patient with multifocal intrahepatic disease underwent liver transplantation 3 months after carbon ion therapy. During radiotherapy and the follow-up period no severe adverse events have occurred. We report the first clinical results of patients with HCC undergoing carbon ion therapy using the rasterscanning technique at our institution. All patients are locally controlled and experienced no higher toxicities in a short follow-up period. Further patients will be included in our prospective Phase-I clinical trial PROMETHEUS-01 (NCT01167374)

  9. Beam-Beam Effects

    CERN Document Server

    Herr, W

    2014-01-01

    One of the most severe limitations in high-intensity particle colliders is the beam-beam interaction, i.e. the perturbation of the beams as they cross the opposing beams. This introduction to beam-beam effects concentrates on a description of the phenomena that are present in modern colliding beam facilities.

  10. Recent advances in electron-beam curing of carbon fiber-reinforced composites

    Science.gov (United States)

    Coqueret, Xavier; Krzeminski, Mickael; Ponsaud, Philippe; Defoort, Brigitte

    2009-07-01

    Cross-linking polymerization initiated by high-energy radiation is a very attractive technique for the fabrication of high-performance composite materials. The method offers many advantages compared to conventional energy- and time-consuming thermal curing processes. Free radical and cationic poly-addition chemistries have been investigated in some details by various research groups along the previous years. A high degree of control over curing kinetics and material properties can be exerted by adjusting the composition of matrix precursors as well as by acting on process parameters. However, the comparison with state-of-the-art thermally cured composites revealed the lower transverse mechanical properties of radiation-cured composites and the higher brittleness of the radiation-cured matrix. Improving fiber-matrix adhesion and upgrading polymer network toughness are thus two major challenges in this area. We have investigated several points related to these issues, and particularly the reduction of the matrix shrinkage on curing, the wettability of carbon fibers, the design of fiber-matrix interface and the use of thermoplastic toughening agents. Significant improvements were achieved on transverse strain at break by applying original surface treatments on the fibers so as to induce covalent coupling with the matrix. A drastic enhancement of the K IC value exceeding 2 MPa m 1/2 was also obtained for acrylate-based matrices toughened with high T g thermoplastics.

  11. Test Measurements of a 20 ms-1 Carbon Wire Beam Scanner

    CERN Document Server

    De Freitas, J; Emery, J; Herranz Alvarez, J F; Koujili, M; Ramos, D; Sapinski, M; Ait-Amira, Y; Djerdir, A

    2011-01-01

    This paper pre­sents the de­sign of the ac­tu­a­tor for the fast and high ac­cu­ra­cy Wire Scan­ner sys­tem. The ac­tu­a­tor con­sists of a ro­tary brushless syn­chronous motor with the per­ma­nent mag­net rotor in­stalled in­side the vac­u­um cham­ber and the sta­tor in­stalled out­side. The fork, per­ma­nent mag­net rotor and two an­gu­lar po­si­tion sen­sors are mount­ed on the same axis and lo­cat­ed in­side the beam vac­u­um cham­ber. The system has to re­sist a bake-out tem­per­a­ture of 200 C and ion­iz­ing radi­a­tion up to tenths of kGy/year. Max­i­mum wire trav­el­ling speed of 20 m/s and a po­si­tion mea­sure­ment ac­cu­ra­cy of 4 um is re­quired. Therefore, the sys­tem must avoid gen­er­at­ing vi­bra­tion and electromagnet­ic in­ter­fer­ence. A dig­i­tal feed­back con­troller will allow max­i­mum flex­i­bil­i­ty for the loop pa­ram­e­ters and feeds the 3-phase lin­ear power driv­er. The per­for­mance of the pr...

  12. Modeling the Effects of Beam Size and Flaw Morphology on Ultrasonic Pulse/Echo Sizing of Delaminations in Carbon Composites

    Science.gov (United States)

    Margetan, Frank J.; Leckey, Cara A.; Barnard, Dan

    2012-01-01

    The size and shape of a delamination in a multi-layered structure can be estimated in various ways from an ultrasonic pulse/echo image. For example the -6dB contours of measured response provide one simple estimate of the boundary. More sophisticated approaches can be imagined where one adjusts the proposed boundary to bring measured and predicted UT images into optimal agreement. Such approaches require suitable models of the inspection process. In this paper we explore issues pertaining to model-based size estimation for delaminations in carbon fiber reinforced laminates. In particular we consider the influence on sizing when the delamination is non-planar or partially transmitting in certain regions. Two models for predicting broadband sonic time-domain responses are considered: (1) a fast "simple" model using paraxial beam expansions and Kirchhoff and phase-screen approximations; and (2) the more exact (but computationally intensive) 3D elastodynamic finite integration technique (EFIT). Model-to-model and model-to experiment comparisons are made for delaminations in uniaxial composite plates, and the simple model is then used to critique the -6dB rule for delamination sizing.

  13. Electron beam generation and structure of defects in carbon and boron nitride nano-tubes

    Energy Technology Data Exchange (ETDEWEB)

    Zobelli, A

    2007-10-15

    The nature and role of defects is of primary importance to understand the physical properties of C and BN (boron nitride) single walled nano-tubes (SWNTs). Transmission electron microscopy (TEM) is a well known powerful tool to study the structure of defects in materials. However, in the case of SWNTs, the electron irradiation of the TEM may knock out atoms. This effect may alter the native structure of the tube, and has also been proposed as a potential tool for nano-engineering of nano-tubular structures. Here we develop a theoretical description of the irradiation mechanism. First, the anisotropy of the emission energy threshold is obtained via density functional based calculations. Then, we numerically derive the total Mott cross section for different emission sites of carbon and boron nitride nano-tubes with different chiralities. Using a dedicated STEM (Scanning Transmission Electron Microscope) microscope with experimental conditions optimised on the basis of derived cross-sections, we are able to control the generation of defects in nano-tubular systems. Either point or line defects can be obtained with a spatial resolution of a few nanometers. The structure, energetics and electronics of point and line defects in BN systems have been investigated. Stability of mono- and di- vacancy defects in hexagonal boron nitride layers is investigated, and their activation energies and reaction paths for diffusion have been derived using the nudged elastic band method (NEB) combined with density functional based techniques. We demonstrate that the appearance of extended linear defects under electron irradiation is more favorable than a random distribution of point defects and this is due to the existence of preferential sites for atom emission in the presence of pre-existing defects, rather than thermal vacancy nucleation and migration. (author)

  14. Beam Simulation Tools for GEANT4 (BT-V1.0). User's Guide

    Energy Technology Data Exchange (ETDEWEB)

    Elvira, V. Daniel [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States). Computational Physics Dept.; Lebrum, P. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States). Computational Physics Dept.; Spentzouris, P. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States). Computational Physics Dept.

    2002-12-02

    Geant4 is a tool kit developed by a collaboration of physicists and computer professionals in the high energy physics field for simulation of the passage of particles through matter. The motivation for the development of the Beam Tools is to extend the Geant4 applications to accelerator physics. The Beam Tools are a set of C++ classes designed to facilitate the simulation of accelerator elements: r.f. cavities, magnets, absorbers, etc. These elements are constructed from Geant4 solid volumes like boxes, tubes, trapezoids, or spheers. There are many computer programs for beam physics simulations, but Geant4 is ideal to model a beam through a material or to integrate a beam line with a complex detector. There are many such examples in the current international High Energy Physics programs. For instance, an essential part of the R&D associated with the Neutrino Source/Muon Collider accelerator is the ionization cooling channel, which is a section of the system aimed to reduce the size of the muon beam in phase space. The ionization cooling technique uses a combination of linacs and light absorbers to reduce the transverse momentum and size of the beam, while keeping the longitudinal momentum constant. The MuCool/MICE (muon cooling) experiments need accurate simulations of the beam transport through the cooling channel in addition to a detailed simulation of the detectors designed to measure the size of the beam. The accuracy of the models for physics processes associated with muon ionization and multiple scattering is critical in this type of applications. Another example is the simulation of the interaction region in future accelerators. The high luminosity and background environments expected in the Next Linear Collider (NLC) and the Very Large Hadron Collider (VLHC) pose great demand on the detectors, which may be optimized by means of a simulation of the detector-accelerator interface.

  15. Downregulation of carbonic anhydrase IX promotes Col10a1 expression in chondrocytes.

    Directory of Open Access Journals (Sweden)

    Toshifumi Maruyama

    Full Text Available Carbonic anhydrase (CA IX is a transmembrane isozyme of CAs that catalyzes reversible hydration of CO(2. While it is known that CA IX is distributed in human embryonic chondrocytes, its role in chondrocyte differentiation has not been reported. In the present study, we found that Car9 mRNA and CA IX were expressed in proliferating but not hypertrophic chondrocytes. Next, we examined the role of CA IX in the expression of marker genes of chondrocyte differentiation in vitro. Introduction of Car9 siRNA to mouse primary chondrocytes obtained from costal cartilage induced the mRNA expressions of Col10a1, the gene for type X collagen α-1 chain, and Epas1, the gene for hypoxia-responsible factor-2α (HIF-2α, both of which are known to be characteristically expressed in hypertrophic chondrocytes. On the other hand, forced expression of CA IX had no effect of the proliferation of chondrocytes or the transcription of Col10a1 and Epas1, while the transcription of Col2a1 and Acan were up-regulated. Although HIF-2α has been reported to be a potent activator of Col10a1 transcription, Epas1 siRNA did not suppress Car9 siRNA-induced increment in Col10a1 expression, indicating that down-regulation of CA IX induces the expression of Col10a1 in chondrocytes in a HIF-2α-independent manner. On the other hand, cellular cAMP content was lowered by Car9 siRNA. Furthermore, the expression of Col10a1 mRNA after Car9 silencing was augmented by an inhibitor of protein kinase A, and suppressed by an inhibitor for phosphodiesterase as well as a brominated analog of cAMP. While these results suggest a possible involvement of cAMP-dependent pathway, at least in part, in induction of Col10a1 expression by down-regulation of Car9, more detailed study is required to clarify the role of CA IX in regulation of Col10a1 expression in chondrocytes.

  16. Carbon-ion beams effectively induce growth inhibition and apoptosis in human neural stem cells compared with glioblastoma A172 cells

    International Nuclear Information System (INIS)

    Carbon-ion radiotherapy (CIRT) holds promise in the treatment of glioblastoma, an aggressive X-ray–resistant brain tumor. However, since glioblastoma cells show a highly invasive nature, carbon-ion (C-ion) irradiation of normal tissues surrounding the tumor is inevitable. Recent studies have revealed the existence of neural stem cells in the adult brain. Therefore, the damaging effect of C-ion beams on the neural stem cells has to be carefully considered in the treatment planning of CIRT. Here, we investigated the growth and death mode of human neural stem cells (hNSCs) and glioblastoma A172 cells after X-ray or C-ion beam irradiation. The X-ray dose resulting in a 50% growth rate (D50) was 0.8 Gy in hNSCs and 3.0 Gy in A172 cells, while the D50 for C-ion beams was 0.4 Gy in hNSCs and 1.6 Gy in A172 cells; the relative biological effectiveness value of C-ion beams was 2.0 in hNSCs and 1.9 in A172 cells. Importantly, both X-rays and C-ion beams preferentially induced apoptosis, not necrosis, in hNSCs; however, radiation-induced apoptosis was less evident in A172 cells. The apoptosis-susceptible nature of the irradiated hNSCs was associated with prolonged upregulation of phosphorylated p53, whereas the apoptosis-resistant nature of A172 cells was associated with a high basal level of nuclear factor kappa B expression. Taken together, these data indicate that apoptosis is the major cell death pathway in hNSCs after irradiation. The high sensitivity of hNSCs to C-ion beams underscores the importance of careful target volume delineation in the treatment planning of CIRT for glioblastoma. (author)

  17. Measurement of analyzing powers of π+ and π- produced on a hydrogen and a carbon target with a 22-GeV/c incident polarized proton beam

    International Nuclear Information System (INIS)

    The analyzing powers of π+ and π- were measured using an incident 22-GeV/c transversely polarized proton beam at the Brookhaven Alternating Gradient Synchrotron. A magnetic spectrometer measured π± inclusive asymmetries on a hydrogen and a carbon target. An elastic polarimeter with a CH2 target measured pp elastic-scattering asymmetries to determine the beam polarization using published data for the pp elastic analyzing power. Using the beam polarization determined from the elastic polarimeter and asymmetries from the inclusive spectrometer, analyzing powers AN for π± were determined in the xF and pT ranges (0.45-0.8) and (0.3-1.2 GeV/c), respectively. The analyzing power results are similar in both sign and character to other measurements at 200 and 11.7 GeV/c, confirming the expectation that high-energy pion inclusive analyzing powers remain large and relatively energy independent. This suggests that pion inclusive polarimetry may be a suitable method for measuring future beam polarizations at BNL RHIC or DESY HERA. Analyzing powers of π+ and π- produced on hydrogen and carbon targets are the same. Various models to explain inclusive analyzing powers are also discussed

  18. Cluster analysis of particulate matter (PM10) and black carbon (BC) concentrations

    Science.gov (United States)

    Žibert, Janez; Pražnikar, Jure

    2012-09-01

    The monitoring of air-pollution constituents like particulate matter (PM10) and black carbon (BC) can provide information about air quality and the dynamics of emissions. Air quality depends on natural and anthropogenic sources of emissions as well as the weather conditions. For a one-year period the diurnal concentrations of PM10 and BC in the Port of Koper were analysed by clustering days into similar groups according to the similarity of the BC and PM10 hourly derived day-profiles without any prior assumptions about working and non-working days, weather conditions or hot and cold seasons. The analysis was performed by using k-means clustering with the squared Euclidean distance as the similarity measure. The analysis showed that 10 clusters in the BC case produced 3 clusters with just one member day and 7 clusters that encompasses more than one day with similar BC profiles. Similar results were found in the PM10 case, where one cluster has a single-member day, while 7 clusters contain several member days. The clustering analysis revealed that the clusters with less pronounced bimodal patterns and low hourly and average daily concentrations for both types of measurements include the most days in the one-year analysis. A typical day profile of the BC measurements includes a bimodal pattern with morning and evening peaks, while the PM10 measurements reveal a less pronounced bimodality. There are also clusters with single-peak day-profiles. The BC data in such cases exhibit morning peaks, while the PM10 data consist of noon or afternoon single peaks. Single pronounced peaks can be explained by appropriate cluster wind speed profiles. The analysis also revealed some special day-profiles. The BC cluster with a high midnight peak at 30/04/2010 and the PM10 cluster with the highest observed concentration of PM10 at 01/05/2010 (208.0 μg m-3) coincide with 1 May, which is a national holiday in Slovenia and has very strong tradition of bonfire parties. The clustering of

  19. Improvement of spread-out Bragg peak flatness for a carbon-ion beam by the use of a ridge filter with a ripple filter.

    Science.gov (United States)

    Hara, Yousuke; Takada, Yoshihisa; Hotta, Kenji; Tansho, Ryohei; Nihei, Tetsuya; Suzuki, Yojiro; Nagafuchi, Kosuke; Kawai, Ryuichi; Tanabe, Masaki; Mizutani, Shohei; Himukai, Takeshi; Matsufuji, Naruhiro

    2012-03-21

    We have developed a novel design method of ridge filters for carbon-ion therapy using a broad-beam delivery system to improve the flatness of a biologically effective dose in the spread-out Bragg peak (SOBP). So far, the flatness of the SOBP is limited to about ±5% for carbon beams since the weight control of component Bragg curves composing the SOBP is difficult. This difficulty arises from using a large number of ridge-bar steps (e.g. about 100 for a SOBP width of 60 mm) required to form the SOBP for the pristine Bragg curve with an extremely sharp distal falloff. Instead of using a single ridge filter, we introduce a ripple filter to broaden the Bragg peak so that the number of ridge-bar steps can be reduced to about 30 for SOBP with of 60 mm for the ridge filter designed for the broadened Bragg peak. Thus we can manufacture the ridge filter more accurately and then attain a better flatness of the SOBP due to well-controlled weights of the component Bragg curves. We placed the ripple filter on the same frame of the ridge filter and arranged the direction of the ripple-filter-bar array perpendicular to that of the ridge-filter-bar array. We applied this method to a 290 MeV u(-1) carbon-ion beam in Heavy Ion Medical Accelerator in Chiba and verified the effectiveness by measurements.

  20. Protective Sliding Carbon-Based Nanolayers Prepared by Argon or Nitrogen Ion-Beam Assisted Deposition on Ti6Al4V Alloy

    Directory of Open Access Journals (Sweden)

    Petr Vlcak

    2016-01-01

    Full Text Available The microstructure and the surface properties of samples coated by carbon-based nanolayer were investigated in an effort to increase the surface hardness and reduce the coefficient of friction of the Ti6Al4V alloy. Protective carbon-based nanolayers were fabricated by argon or nitrogen ion-beam assisted deposition at ion energy of 700 eV on Ti6Al4V substrates. The Raman spectra indicated that nanolayers had a diamond-like carbon character with sp2 rich bonds. The TiC and TiN compounds formed in the surface area were detected by X-ray diffraction. Nanoscratch tests showed increased adhesion of a carbon-based nanolayer deposited with ion assistance in comparison with a carbon nanolayer deposited without ion assistance. The results showed that argon ion assistance leads to greater nanohardness than a sample coated by a carbon-based nanolayer with nitrogen ion assistance. A more than twofold increase in nanohardness and a more than fivefold decrease in the coefficient of friction were obtained for samples coated by a carbon-based nanolayer with ion assistance, in comparison with the reference sample.

  1. Evaluation of nuclear reaction cross-sections and fragment yields in carbon beams using the SHIELD-HIT Monte Carlo code. Comparison with experiments

    International Nuclear Information System (INIS)

    In light ion therapy, the knowledge of the spectra of both primary and secondary particles in the target volume is needed in order to accurately describe the treatment. The transport of ions in matter is complex and comprises both atomic and nuclear processes involving primary and secondary ions produced in the cascade of events. One of the critical issues in the simulation of ion transport is the modeling of inelastic nuclear reaction processes, in which projectile nuclei interact with target nuclei and give rise to nuclear fragments. In the Monte Carlo code SHIELD-HIT, inelastic nuclear reactions are described by the Many Stage Dynamical Model (MSDM), which includes models for the different stages of the interaction process. In this work, the capability of SHIELD-HIT to simulate the nuclear fragmentation of carbon ions in tissue-like materials was studied. The value of the parameter κ, which determines the so-called freeze-out volume in the Fermi break-up stage of the nuclear interaction process, was adjusted in order to achieve better agreement with experimental data. In this paper, results are shown both with the default value κ = 1 and the modified value κ = 10 which resulted in the best overall agreement. Comparisons with published experimental data were made in terms of total and partial charge-changing cross-sections generated by the MSDM, as well as integral and differential fragment yields simulated by SHIELD-HIT in intermediate and thick water targets irradiated with a beam of 400 MeV u−112C ions. Better agreement with the experimental data was in general obtained with the modified parameter value (κ = 10), both on the level of partial charge-changing cross-sections and fragment yields. (paper)

  2. Electrical characterization of electron beam induced damage on sub-10 nm n-channel MOS transistors using nano-probing technique

    Science.gov (United States)

    Kang, Jonghyuk; Lee, Sungho; Choi, Byoungdeog

    2016-11-01

    Electron beam induced damage on sub-10 nm n-channel MOS transistors was evaluated using an atomic force microscopy-based nano-probing technique. After electron beam irradiation, all the device parameters shifted including threshold voltage (V th), saturation current, sub-threshold slope and transistor leakage current. A negative shift in V th occurred at low electron beam acceleration voltage (V acc) because of the increase in oxide trapped holes generated by excited plasmons. At high V acc, however, a positive V th shift was observed because of an increased contribution of interface trap generation caused by the deeper electron penetration depth. In addition, interface trap generation not only degraded the sub-threshold slope due to the additional capacitance from the generated interface traps, but also increased transistor leakage current due to changes in junction characteristics. Our studies show that it is critical to avoid electron beam exposure before electrical characterization on sub-10 nm devices even in the range of less than 1.0 kV of V acc using nano-probe systems.

  3. Four-dimensional layer-stacking carbon-ion beam dose distribution by use of a lung numeric phantom.

    Science.gov (United States)

    Mori, Shinichiro; Kumagai, Motoki; Miki, Kentaro

    2015-07-01

    To extend layer-stacking irradiation to accommodate intrafractional organ motion, we evaluated the carbon-ion layer-stacking dose distribution using a numeric lung phantom. We designed several types of range compensators. The planning target volume was calculated from the respective respiratory phases for consideration of intrafractional beam range variation. The accumulated dose distribution was calculated by registering of the dose distributions at respective phases to that at the reference phase. We evaluated the dose distribution based on the following six parameters: motion displacement, direction, gating window, respiratory cycle, range-shifter change time, and prescribed dose. All parameters affected the dose conformation to the moving target. By shortening of the gating window, dose metrics for superior-inferior (SI) and anterior-posterior (AP) motions were decreased from a D95 of 94 %, Dmax of 108 %, and homogeneity index (HI) of 23 % at T00-T90, to a D95 of 93 %, Dmax of 102 %, and HI of 20 % at T40-T60. In contrast, all dose metrics except the HI were independent of respiratory cycle. All dose metrics in SI motion were almost the same in respective motion displacement, with a D95 of 94 %, Dmax of 108 %, Dmin of 89 %, and HI of 23 % for the ungated phase, and D95 of 93 %, Dmax of 102 %, Dmin of 85 %, and HI of 20 % for the gated phase. The dose conformation to a moving target was improved by the gating strategy and by an increase in the prescribed dose. A combination of these approaches is a practical means of adding them to existing treatment protocols without modifications.

  4. Response of CR39 track etch detector to 10 A GeV Fe 26+ ion beam and total charge changing cross section measurement

    Science.gov (United States)

    Kumar, A.; Gupta, R.; Jalota, S.; Giacomelli, G.; Patrizii, L.; Togo, V.

    2012-01-01

    Total charge changing cross-section of 10 A GeV Fe 26+ ion beam on polyethylene and CR39 targets was measured. Charge of the fragments of projectiles was detected using CR39 nuclear track detectors by a new technique of one-side etching using an automated optical microscope with an image analysing software. The calculated value of total charge changing cross-section is σ tot = (2694 ± 142)mb and is in good agreement with the experimental values by other methods within error. The restricted energy loss ( REL) at energy 10 A GeV for all the fragments was theoretically calculated by using Bethe-Bloch equation and then obtained a calibration curve of reduced etch-rate ratio ( p) versus REL showing the response of CR39 track detectors to 10 A GeV Fe 26+ beam. The curve was fitted by a polynomial showing the relation between p and REL.

  5. Measurement of Neutral Current Neutral Pion Production on Carbon in a Few-GeV Neutrino Beam

    Energy Technology Data Exchange (ETDEWEB)

    Kurimoto, Yoshinori [Kyoto Univ. (Japan)

    2010-01-01

    Understanding of the π0 production via neutrino-nucleus neutral current interaction in the neutrino energy region of a few GeV is essential for the neutrino oscillation experiments. In this thesis, we present a study of neutral current π0 production from muon neutrinos scattering on a polystyrene (C8H8) target in the SciBooNE experiment. All neutrino beam data corresponding to 0.99 × 1020 protons on target have been analyzed. We have measured the cross section ratio of the neutral current π0 production to the total charge current interaction and the π0 kinematic distribution such as momentum and direction. We obtain [7.7 ± 0.5(stat.) ± 0.5(sys.)] × 10-2 as the ratio of the neutral current neutral pion production to total charged current cross section; the mean energy of neutrinos producing detected neutral pions is 1.1 GeV. The result agrees with the Rein- Sehgal model, which is generally used for the Monte Carlo simulation by many neutrino oscillation experiments. We achieve less than 10 % uncertainty which is required for the next generation search for νµ → νe oscillation. The spectrum shape of the π0 momentum and the distribution of the π0 emitted angle agree with the prediction, which means that not only the Rein-Sehgal model but also the intra-nuclear interaction models describe our data well. We also measure the ratio of the neutral current coherent pion production to total charged current cross section to be (1.17 ± 0.23 ) × 10-2 based on the Rein and Sehgal model. The result gives the evidence for non-zero coherent pion production via neutral current interaction at the mean neutrino energy of 1.0 GeV.

  6. The effects of carbon foil on beams in stripping-accumulation of a heavy-ion synchrotron

    International Nuclear Information System (INIS)

    Stripping-injection scheme is adopted in the synchrotron of an accelerator complex named as HITFiL. HITFIL is dedicated to cancer therapy. High intensity can be reached by using the stripping-injection as the limit of Liouville's theorem is broken due to charge-exchange. But unavoidable traversals of the circulating beams through the foil may cause beam-losses and deteriorations of beam quality, including: 1) beam-losses caused by an alteration of the particles' charge state; 2) emittance growth caused by Multiple Coulomb Scattering; and 3) decrease of mean-momentum and growth of momentum spread induced by energy loss and energy loss straggling. In this paper, the model of particle-foil interaction is established by Monte Carlo processes. The effects of the stripping foil on beams are studied based on an improvement of the ACCSIM code. (authors)

  7. TH-E-17A-10: Markerless Lung Tumor Tracking Based On Beams Eye View EPID Images

    Energy Technology Data Exchange (ETDEWEB)

    Chiu, T; Kearney, V; Liu, H; Jiang, L; Foster, R; Mao, W [UT Southwestern Medical Center, Dallas, Texas (United States); Rozario, T; Bereg, S [University of Texas at Dallas, Richardson, Texas (United States); Klash, S [Premier Cancer Centers, Dallas, TX (United States)

    2014-06-15

    Purpose: Dynamic tumor tracking or motion compensation techniques have proposed to modify beam delivery following lung tumor motion on the flight. Conventional treatment plan QA could be performed in advance since every delivery may be different. Markerless lung tumor tracking using beams eye view EPID images provides a best treatment evaluation mechanism. The purpose of this study is to improve the accuracy of the online markerless lung tumor motion tracking method. Methods: The lung tumor could be located on every frame of MV images during radiation therapy treatment by comparing with corresponding digitally reconstructed radiograph (DRR). A kV-MV CT corresponding curve is applied on planning kV CT to generate MV CT images for patients in order to enhance the similarity between DRRs and MV treatment images. This kV-MV CT corresponding curve was obtained by scanning a same CT electron density phantom by a kV CT scanner and MV scanner (Tomotherapy) or MV CBCT. Two sets of MV DRRs were then generated for tumor and anatomy without tumor as the references to tracking the tumor on beams eye view EPID images. Results: Phantom studies were performed on a Varian TrueBeam linac. MV treatment images were acquired continuously during each treatment beam delivery at 12 gantry angles by iTools. Markerless tumor tracking was applied with DRRs generated from simulated MVCT. Tumors were tracked on every frame of images and compared with expected positions based on programed phantom motion. It was found that the average tracking error were 2.3 mm. Conclusion: This algorithm is capable of detecting lung tumors at complicated environment without implanting markers. It should be noted that the CT data has a slice thickness of 3 mm. This shows the statistical accuracy is better than the spatial accuracy. This project has been supported by a Varian Research Grant.

  8. TH-E-17A-10: Markerless Lung Tumor Tracking Based On Beams Eye View EPID Images

    International Nuclear Information System (INIS)

    Purpose: Dynamic tumor tracking or motion compensation techniques have proposed to modify beam delivery following lung tumor motion on the flight. Conventional treatment plan QA could be performed in advance since every delivery may be different. Markerless lung tumor tracking using beams eye view EPID images provides a best treatment evaluation mechanism. The purpose of this study is to improve the accuracy of the online markerless lung tumor motion tracking method. Methods: The lung tumor could be located on every frame of MV images during radiation therapy treatment by comparing with corresponding digitally reconstructed radiograph (DRR). A kV-MV CT corresponding curve is applied on planning kV CT to generate MV CT images for patients in order to enhance the similarity between DRRs and MV treatment images. This kV-MV CT corresponding curve was obtained by scanning a same CT electron density phantom by a kV CT scanner and MV scanner (Tomotherapy) or MV CBCT. Two sets of MV DRRs were then generated for tumor and anatomy without tumor as the references to tracking the tumor on beams eye view EPID images. Results: Phantom studies were performed on a Varian TrueBeam linac. MV treatment images were acquired continuously during each treatment beam delivery at 12 gantry angles by iTools. Markerless tumor tracking was applied with DRRs generated from simulated MVCT. Tumors were tracked on every frame of images and compared with expected positions based on programed phantom motion. It was found that the average tracking error were 2.3 mm. Conclusion: This algorithm is capable of detecting lung tumors at complicated environment without implanting markers. It should be noted that the CT data has a slice thickness of 3 mm. This shows the statistical accuracy is better than the spatial accuracy. This project has been supported by a Varian Research Grant

  9. Fragmentation of 200 and 244 MeV/u carbon beams in thick tissue-like absorbers

    International Nuclear Information System (INIS)

    Stacks consisting of thin CR-39 sheets sandwiched between thick lucite and water absorbers were perpendicularly bombarded by 12C ions at 200 and 244 MeV/u. Track radius distributions representing the charge composition of the fragmented beams were automatically measured by a particle track analysis system. After analysis of the nuclear charge distributions, the total charge removal cross-sections and elemental production cross-sections of fragments with atomic numbers from 5 to 3, were obtained down to the lower energies (∼50 and 100 MeV/u, respectively). It has been found that the measured total charge removal cross-section agrees with theoretical predictions within ∼10% and very well with previous experiments in corresponding energy regions. Two model calculations for production of B fragment are in good agreement with our measured data while a third model overestimates it by ∼12%. Theoretical cross-sections for Be and Li fragments differ strongly among the different models and from measured values

  10. ANSYS simulation study on displacement of carbon fiber reinforced concrete beam%碳纤维加固混凝土梁位移ANSYS模拟研究

    Institute of Scientific and Technical Information of China (English)

    王良超; 杨治华; 刘敏

    2012-01-01

    For beam mid-span displacement, theoretical calculation and ANSYS modeling computational analysis have been done to quantitative analysis of the effect of carbon fiber reinforcement beam, and improve the further relevant reinforcement theory, to provide a theoretical and com- putational support for real-strengthening works. The analysis shows that the values and trends of finite element analysis and theoretical calculations are very similar, which indicates that the finite element analysis is capable to simulate the beam actual stress state, the displacement of FRP rein- forced beam decreases 14.08%.%针对梁体跨中位移,通过理论计算以及ANSYS建模分析计算分析比较,定量分析碳纤维加固梁体的效果,进一步完善相关加固理论,为现实加固工程提供理论和计算支持,分析表明,有限元分析计算值和理论计算值在数值和发展趋势上都有很大的相似性,说明有限元分析能较好的模拟梁体实际受力状态,FRP加固后梁体位移减小14.08%。

  11. Pore size effects on the sorption of supercritical carbon dioxide in mesoporous CPG-10 silica

    Energy Technology Data Exchange (ETDEWEB)

    Rother, Gernot [ORNL; Krukowski, Elizabeth G [ORNL; Wallacher, Dirk [Helmholtz-Zentrum Berlin; Grimm, Nico [Helmholtz-Zentrum Berlin; Bodnar, Robert J [ORNL; Cole, David [Ohio State University

    2012-01-01

    Excess sorption isotherms of supercritical carbon dioxide in mesoporous CPG-10 silica glasses with nominal pore sizes of 75 (7.5 nm) and 350 (35 nm) were measured gravimetrically at 35 C and 50 C and pressures of 0-200 bar. Formation of broad maxima in the excess sorption was observed at fluid densities below the bulk critical density. Positive values of excess sorption were measured at bulk densities below about 0.65-0.7 g/cm3, whereas zero and negative values were obtained at higher densities, indicating that the interfacial fluid becomes less dense than the corresponding bulk fluid at high fluid densities. A shift of the excess sorption peak position to higher fluid density is found with increasing pore width. The excess sorption of CO2 normalized to the specific surface area is higher for the 35 nm pore size material, suggesting pore confinement effects. Conversely, the pore volume normalized excess sorption is higher for the 7.5 nm pore size material. Assessment of mean pore density reveals regions of constant pore fluid density, located between the excess sorption peak and the adsorption/depletion transition. Both materials exhibit such regions of constant mean pore fluid density as a function of bulk CO2 density at the lower temperature of 35 C, but not at 50 C. The results of this study suggest that the CO2 storage capacity in quartz-rich reservoirs is higher for sites with low temperature and rock textures characterized by narrow pores with high surface to volume ratios.

  12. Diagnostics of electron beam properties from the simultaneous hard X-ray and microwave emission in the 10 March 2001 flare

    CERN Document Server

    Zharkova, V V; Kashapova, L K; Kuznetsov, A A; Altyntsev, A T

    2011-01-01

    Simultaneous simulation of HXR and MW emission with the same populations of electrons is still a great challenge for interpretation of observations in real events. In this paper we apply the FP kinetic model of precipitation of electron beam with energy range from 12 keV to 1.2 MeV to the interpretation of X-ray and microwave emissions observed in the flare of 10 March 2001. Methods. The theoretical HXR and MW emissions were calculated by using the distribution functions of electron beams found by solving time-dependent Fokker-Planck approach in a converging magnetic field (Zharkova at al., 2010; Kuznetsov and Zharkova, 2010) for anisotropic scattering of beam electrons on the ambient particles in Coloumb collisions and Ohmic losses. The simultaneous observed HXR photon spectra and frequency distribution of MW emission and polarization were fit by those simulated from FP models which include the effects of electric field induced by beam electrons and precipitation into a converging magnetic loop. Magnetic fie...

  13. Low-dose patterning of platinum nanoclusters on carbon nanotubes by focused-electron-beam-induced deposition as studied by TEM

    Directory of Open Access Journals (Sweden)

    Xiaoxing Ke

    2013-02-01

    Full Text Available Focused-electron-beam-induced deposition (FEBID is used as a direct-write approach to decorate ultrasmall Pt nanoclusters on carbon nanotubes at selected sites in a straightforward maskless manner. The as-deposited nanostructures are studied by transmission electron microscopy (TEM in 2D and 3D, demonstrating that the Pt nanoclusters are well-dispersed, covering the selected areas of the CNT surface completely. The ability of FEBID to graft nanoclusters on multiple sides, through an electron-transparent target within one step, is unique as a physical deposition method. Using high-resolution TEM we have shown that the CNT structure can be well preserved thanks to the low dose used in FEBID. By tuning the electron-beam parameters, the density and distribution of the nanoclusters can be controlled. The purity of as-deposited nanoclusters can be improved by low-energy electron irradiation at room temperature.

  14. Effects of beam interruption time on tumor control probability in single-fractionated carbon-ion radiotherapy for non-small cell lung cancer

    International Nuclear Information System (INIS)

    Carbon-ion radiotherapy treatment plans are designed on the assumption that the beams are delivered instantaneously, irrespective of actual dose-delivery time structure in a treatment session. As the beam lines are fixed in the vertical and horizontal directions at our facility, beam delivery is interrupted in multi-field treatment due to the necessity of patient repositioning within the fields. Single-fractionated treatment for non-small cell lung cancer (NSCLC) is such a case, in which four treatment fields in multiple directions are delivered in one session with patient repositioning during the session. The purpose of this study was to investigate the effects of the period of dose delivery, including interruptions due to patient repositioning, on tumor control probability (TCP) of NSCLC. All clinical doses were weighted by relative biological effectiveness (RBE) evaluated for instantaneous irradiation. The rate equations defined in the microdosimetric kinetic model (MKM) for primary lesions induced in DNA were applied to the single-fractionated treatment of NSCLC. Treatment plans were made for an NSCLC case for various prescribed doses ranging from 25 to 50 Gy (RBE), on the assumption of instantaneous beam delivery. These plans were recalculated by varying the interruption time τ ranging from 0 to 120 min between the second and third fields for continuous irradiations of 3 min per field based on the MKM. The curative doses that would result in a TCP of 90% were deduced for the respective interruption times. The curative dose was 34.5 Gy (RBE) for instantaneous irradiation and 36.6 Gy (RBE), 39.2 Gy (RBE), 41.2 Gy (RBE), 43.3 Gy (RBE) and 44.4 Gy (RBE) for τ = 0 min, 15 min, 30 min, 60 min and 120 min, respectively. The realistic biological effectiveness of therapeutic carbon-ion beam decreased with increasing interruption time. These data suggest that the curative dose can increase by 20% or more compared to the planned dose if

  15. Effects of beam interruption time on tumor control probability in single-fractionated carbon-ion radiotherapy for non-small cell lung cancer

    Science.gov (United States)

    Inaniwa, T.; Kanematsu, N.; Suzuki, M.; Hawkins, R. B.

    2015-05-01

    Carbon-ion radiotherapy treatment plans are designed on the assumption that the beams are delivered instantaneously, irrespective of actual dose-delivery time structure in a treatment session. As the beam lines are fixed in the vertical and horizontal directions at our facility, beam delivery is interrupted in multi-field treatment due to the necessity of patient repositioning within the fields. Single-fractionated treatment for non-small cell lung cancer (NSCLC) is such a case, in which four treatment fields in multiple directions are delivered in one session with patient repositioning during the session. The purpose of this study was to investigate the effects of the period of dose delivery, including interruptions due to patient repositioning, on tumor control probability (TCP) of NSCLC. All clinical doses were weighted by relative biological effectiveness (RBE) evaluated for instantaneous irradiation. The rate equations defined in the microdosimetric kinetic model (MKM) for primary lesions induced in DNA were applied to the single-fractionated treatment of NSCLC. Treatment plans were made for an NSCLC case for various prescribed doses ranging from 25 to 50 Gy (RBE), on the assumption of instantaneous beam delivery. These plans were recalculated by varying the interruption time τ ranging from 0 to 120 min between the second and third fields for continuous irradiations of 3 min per field based on the MKM. The curative doses that would result in a TCP of 90% were deduced for the respective interruption times. The curative dose was 34.5 Gy (RBE) for instantaneous irradiation and 36.6 Gy (RBE), 39.2 Gy (RBE), 41.2 Gy (RBE), 43.3 Gy (RBE) and 44.4 Gy (RBE) for τ = 0 min, 15 min, 30 min, 60 min and 120 min, respectively. The realistic biological effectiveness of therapeutic carbon-ion beam decreased with increasing interruption time. These data suggest that the curative dose can increase by 20% or more compared to the planned dose if the

  16. Measurement of fragment production DDX of 72 and 144 MeV 12C beam induced reaction on carbon using Bragg Curve Counter

    International Nuclear Information System (INIS)

    Double differential cross section (DDX) data of fragment production for 72 (6 MeV/nucleon) and 144 MeV (12 MeV/nucleon) 12C beam induced reaction on carbon were measured using a Bragg Curve Counter (BCC). The DDX data were obtained for fragments of He, Li, Be, B, C, N and O at 30 degree emission angle. Theoretical calculation using PHITS code with QMD+GEM model represents the DDX well except for components from reactions of direct process and α particle clustering process. (author)

  17. Properties of carbon beams for radiotherapy with three different energies: 135 MeV/u, 290 MeV/u and 400 MeV/u

    International Nuclear Information System (INIS)

    Sets of plastic nuclear track detectors, used as spectrometers of linear energy transfer (LET), were exposed to carbon beams at 3 different initial energy levels (135, 290, and 400 MeV/u) obtained from the HIMAC accelerator (NIRS, Chiba, Japan). The detectors were positioned behind PMMA filters of different thickness chosen so as to cover whole area of the Bragg curve. The LET spectra were measured and the dependences of the absorbed dose and other biological weighted factors on the depth were estimated. (orig.)

  18. Development of a monoenergetic 1-10 keV neutral lithium beam for the diagnostic of edge plasmas in magnetic confinement devices

    International Nuclear Information System (INIS)

    Diagnostic of plasmas confined by magnetic fields for fusion research based on neutral lithium beam (NLB) is presently considered to be one of the most appropriate methods to carry out the important measurements of edge density and its fluctuation profiles without plasma perturbation. In this CRP project we proposed the development of an NLB source with 1-10 KeV based on a traditional β-eucryptite surface emission source coupled to a Pierce gun geometry accelerator and subsequent neutralization of the Li+ beam by a Li-oven neutralizer. Possible application of such an NLB probe in a medium term (2-3 years) in our country would be in a small RFP in operation and in a low-aspect-ratio tokamak in construction both at LAP/INPE and in other hot plasma devices operating at brazilian universities of Sao Paulo (USP) and Campinas (UNICAMP) with whom we maintain strong collaboration efforts in plasma research. (author). 8 refs

  19. Cognition and Synaptic-Plasticity Related Changes in Aged Rats Supplemented with 8- and 10-Carbon Medium Chain Triglycerides

    Science.gov (United States)

    Wang, Dongmei; Mitchell, Ellen S.

    2016-01-01

    Brain glucose hypometabolism is a common feature of Alzheimer’s disease (AD). Previous studies have shown that cognition is improved by providing AD patients with an alternate energy source: ketones derived from either ketogenic diet or supplementation with medium chain triglycerides (MCT). Recently, data on the neuroprotective capacity of MCT-derived medium chain fatty acids (MCFA) suggest 8-carbon and 10-carbon MCFA may have cognition-enhancing properties which are not related to ketone production. We investigated the effect of 8 week treatment with MCT8, MCT10 or sunflower oil supplementation (5% by weight of chow diet) in 21 month old Wistar rats. Both MCT diets increased ketones plasma similarly compared to control diet, but MCT diets did not increase ketones in the brain. Treatment with MCT10, but not MCT8, significantly improved novel object recognition memory compared to control diet, while social recognition increased in both MCT groups. MCT8 and MCT10 diets decreased weight compared to control diet, where MCFA plasma levels were higher in MCT10 groups than in MCT8 groups. Both MCT diets increased IRS-1 (612) phosphorylation and decreased S6K phosphorylation (240/244) but only MCT10 increased Akt phosphorylation (473). MCT8 supplementation increased synaptophysin, but not PSD-95, in contrast MCT10 had no effect on either synaptic marker. Expression of Ube3a, which controls synaptic stability, was increased by both MCT diets. Cortex transcription via qPCR showed that immediate early genes related to synaptic plasticity (arc, plk3, junb, egr2, nr4a1) were downregulated by both MCT diets while MCT8 additionally down-regulated fosb and egr1 but upregulated grin1 and gba2. These results demonstrate that treatment of 8- and 10-carbon length MCTs in aged rats have slight differential effects on synaptic stability, protein synthesis and behavior that may be independent of brain ketone levels. PMID:27517611

  20. Cognition and Synaptic-Plasticity Related Changes in Aged Rats Supplemented with 8- and 10-Carbon Medium Chain Triglycerides.

    Science.gov (United States)

    Wang, Dongmei; Mitchell, Ellen S

    2016-01-01

    Brain glucose hypometabolism is a common feature of Alzheimer's disease (AD). Previous studies have shown that cognition is improved by providing AD patients with an alternate energy source: ketones derived from either ketogenic diet or supplementation with medium chain triglycerides (MCT). Recently, data on the neuroprotective capacity of MCT-derived medium chain fatty acids (MCFA) suggest 8-carbon and 10-carbon MCFA may have cognition-enhancing properties which are not related to ketone production. We investigated the effect of 8 week treatment with MCT8, MCT10 or sunflower oil supplementation (5% by weight of chow diet) in 21 month old Wistar rats. Both MCT diets increased ketones plasma similarly compared to control diet, but MCT diets did not increase ketones in the brain. Treatment with MCT10, but not MCT8, significantly improved novel object recognition memory compared to control diet, while social recognition increased in both MCT groups. MCT8 and MCT10 diets decreased weight compared to control diet, where MCFA plasma levels were higher in MCT10 groups than in MCT8 groups. Both MCT diets increased IRS-1 (612) phosphorylation and decreased S6K phosphorylation (240/244) but only MCT10 increased Akt phosphorylation (473). MCT8 supplementation increased synaptophysin, but not PSD-95, in contrast MCT10 had no effect on either synaptic marker. Expression of Ube3a, which controls synaptic stability, was increased by both MCT diets. Cortex transcription via qPCR showed that immediate early genes related to synaptic plasticity (arc, plk3, junb, egr2, nr4a1) were downregulated by both MCT diets while MCT8 additionally down-regulated fosb and egr1 but upregulated grin1 and gba2. These results demonstrate that treatment of 8- and 10-carbon length MCTs in aged rats have slight differential effects on synaptic stability, protein synthesis and behavior that may be independent of brain ketone levels. PMID:27517611

  1. Mycosis fungoides. Electron beam therapy.

    Science.gov (United States)

    Spittle, M F

    1977-01-01

    The most effective treatment of late mycosis fungoides is total skin electron beam therapy. The beam at the Hammersmith Hospital in London has been adapted to treat these patients. Patients with advanced disease who have failed more conservative methods of treatment are irradiated. The electron beam is modified by the use of carbon and copper scatterers to produce an 80 percent depth dose at 5.5, 8 and 11.5 millimeters below the skin surface. The dose achieved in most patients is between 1500 rads and 2600 rads given in 10 to 13 treatments over 5-7 weeks. Recently the higher dose range has been employed and lithium flouride studies have shown that giving these doses from each of 4 fields, the dose achieved on the skin is approximately twice the given dose. The management of patients and the effects of treatment are discussed.

  2. Studies of Adsorption Characteristics of Activated Carbons in between 4.5 to 10 K for Cryopump Applications

    Science.gov (United States)

    Krishnamoorthy, V.; Swarup Udgata, Satya; Shankar Tripathi, Vijai; Gangradey, Ranjana; Kasthurirengan, Srinivasan; Behera, Upendra

    2012-11-01

    Cryosorption pump is the only solution to pump helium, hydrogen and its isotopes in fusion devices. To design such pumps, knowledge of adsorption characteristics of activated carbons in the temperature range from 4.5 to 77 K is needed, but is very scarce in the open literature. Hence an experimental setup is designed and developed to measure adsorption characteristics of activated carbons down to 4.5 K. For this purpose, a commercial micropore analyzer operating down to 77K is coupled to a two-stage GM cryocooler, to enable cooling the sample temperature down to 4.5 K. A heat switch is mounted in between the second stage cold head and the sample chamber helps to vary the sample temperature from 4.5 K to 77K without affecting the performance of the cryocooler. The details of the experimental setup is presented elsewhere. We present here the experimental results of adsorption of different types of activated carbons in the temperature range 4.5K to 10 K using Helium gas as adsorbate. These results are evaluated in terms of surface area, pore sizes and their distributions. Also the effect of epoxy based adhesive used in bonding the activated carbons to the panels is evaluated. These results will be useful towards the selection of the right activated carbons for the development of cryosorption pumps.

  3. Beam-beam effects

    Energy Technology Data Exchange (ETDEWEB)

    Zholents, A.

    1994-12-01

    The term beam-beam effects is usually used to designate different phenomena associated with interactions of counter-rotating beams in storage rings. Typically, the authors speak about beam-beam effects when such interactions lead to an increase of the beam core size or to a reduction of the beam lifetime or to a growth of particle`s population in the beam halo and a correspondent increase of the background. Although observations of beam-beam effects are very similar in most storage rings, it is very likely that every particular case is largely unique and machine-dependent. This constitutes one of the problems in studying the beam-beam effects, because the experimental results are often obtained without characterizing a machine at the time of the experiment. Such machine parameters as a dynamic aperture, tune dependencies on amplitude of particle oscillations and energy, betatron phase advance between the interaction points and some others are not well known, thus making later analysis uncertain. The authors begin their discussion with demonstrations that beam-beam effects are closely related to non linear resonances. Then, they will show that a non linearity of the space charge field is responsible for the excitation of these resonances. After that, they will consider how beam-beam effects could be intensified by machine imperfections. Then, they will discuss a leading mechanism for the formation of the beam halo and will describe a new technique for beam tails and lifetime simulations. They will finish with a brief discussion of the coherent beam-beam effects.

  4. Effect of electron beam irradiation on multi-walled carbon nanotubes%电子束辐照对多壁碳纳米管的影响

    Institute of Scientific and Technical Information of China (English)

    李斌; 凤仪; 丁克望; 钱刚; 张学斌; 刘衍芳

    2014-01-01

    在室温下采用透射电子显微镜中汇聚的电子束辐照多壁碳纳米管。结果表明,在能量为100 keV的电子束辐照下除了碳纳米管管壁有一些弯曲外没有其他结构被破坏;当电子能量增加到200 keV时,纳米管有明显的损伤,可以观察到纳米管的无定型化、纳米管外壁的凹坑和缺口。200 keV的电子束辐照还能形成碳洋葱和2根多壁纳米管的焊接。多壁碳纳米管的离位阀能为83~110 keV。能量超过阀能的电子束可以很轻易地损伤纳米管而低于阀能的电子束则很难损坏纳米管,其损伤机理为溅射和原子离位。%Multi-walled carbon nanotubes (MWCNTs) were irradiated with focused electron beams in a transmission electron microscope at room temperature. The results showed that carbon nanotubes had no obvious structural damages but only shell bending under 100 keV electron beam irradiation. However, when the electron energy increased to 200 keV, the nanotubes were damaged and amorphization, pits and gaps were detected. Furthermore, generating of carbon onions and welding between two MWCNTs occurred under 200 keV electron irradiation. It was easy to destroy the MWCNTs as the electron beams exceeded the displacement threshold energy that was calculated to be 83-110 keV. Conversely, the energy of electron beams below the threshold energy was not able to damage the tubes. The damage mechanism is sputtering and atom displacement.

  5. Investigation of the microstructure, mechanical properties and tribological behaviors of Ti-containing diamond-like carbon films fabricated by a hybrid ion beam method

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Wei [Ningbo Key Laboratory of Marine Protection Materials, Division of Surface Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201 (China); Future Convergence Technology Division, Korea Institute of Science and Technology, Seoul, 130-650 (Korea, Republic of); Ke, Peiling [Ningbo Key Laboratory of Marine Protection Materials, Division of Surface Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201 (China); Moon, Myoung-Woon; Lee, Kwang-Ryeol [Future Convergence Technology Division, Korea Institute of Science and Technology, Seoul, 130-650 (Korea, Republic of); Wang, Aiying, E-mail: aywang@nimte.ac.cn [Ningbo Key Laboratory of Marine Protection Materials, Division of Surface Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201 (China)

    2012-07-31

    Diamond-like carbon (DLC) films with various titanium contents were investigated using a hybrid ion beam system comprising an anode-layer linear ion beam source and a DC magnetron sputtering unit. The film composition and microstructure were characterized carefully by X-ray photoelectron spectroscopy, transmission electron microscopy and Raman spectroscopy, revealing that the doped Ti atoms had high solubility in the DLC films. The maximum solubility was found to lie between about 7 and 13 at.%. When the Ti content was lower than this solubility, the doped Ti atoms dissolved in the DLC matrix and the films exhibited the typical features of the amorphous DLC structure and displayed low compressive stresses, friction coefficients and wear rates. However, as the doped content exceeded the solubility, Ti atoms bonded with C atoms, resulting in the formation of carbide nano-particles embedded in the DLC matrix. Although the emergence of the carbide nano-particles promoted graphitizing due to a catalysis effect, the film hardness was enhanced to a great extent. On the other hand, the hard carbides particles caused abrasive wear behavior, inducing a high friction coefficient and wear rate. - Highlights: Black-Right-Pointing-Pointer Ti doped DLC films (Ti {approx} 24 at.% )were deposited by a hybrid ion beam system. Black-Right-Pointing-Pointer Solubility of the Ti atoms in the DLC films was found around 7 {approx} 13 at .%. Black-Right-Pointing-Pointer Microstructure evolution from DLC to nanocomposite played key role in film behaviors.

  6. DFT Study on One-carbon Unit Transfer from 1,10-CH+-tetrahydroquinoxaline to Methylamine

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Density Funetional Theory (DFT) method was used in this paper to study one-carbon transfer from 1.10-tetrahydroquinoxalinc, an analoguc of tetrahydrofolic aeid, to methylamine.This reaetion can be completedvia two paths. From the computation result we can conclude thai a general-aeid catalysis exists in this reaction. By computation we find DFT has its limitation in deseribing a newly incorporated structure with a unit charge.

  7. Exhaustive Analysis of a Genotype Space Comprising 10(15 Central Carbon Metabolisms Reveals an Organization Conducive to Metabolic Innovation.

    Directory of Open Access Journals (Sweden)

    Sayed-Rzgar Hosseini

    2015-08-01

    Full Text Available All biological evolution takes place in a space of possible genotypes and their phenotypes. The structure of this space defines the evolutionary potential and limitations of an evolving system. Metabolism is one of the most ancient and fundamental evolving systems, sustaining life by extracting energy from extracellular nutrients. Here we study metabolism's potential for innovation by analyzing an exhaustive genotype-phenotype map for a space of 10(15 metabolisms that encodes all possible subsets of 51 reactions in central carbon metabolism. Using flux balance analysis, we predict the viability of these metabolisms on 10 different carbon sources which give rise to 1024 potential metabolic phenotypes. Although viable metabolisms with any one phenotype comprise a tiny fraction of genotype space, their absolute numbers exceed 10(9 for some phenotypes. Metabolisms with any one phenotype typically form a single network of genotypes that extends far or all the way through metabolic genotype space, where any two genotypes can be reached from each other through a series of single reaction changes. The minimal distance of genotype networks associated with different phenotypes is small, such that one can reach metabolisms with novel phenotypes--viable on new carbon sources--through one or few genotypic changes. Exceptions to these principles exist for those metabolisms whose complexity (number of reactions is close to the minimum needed for viability. Increasing metabolic complexity enhances the potential for both evolutionary conservation and evolutionary innovation.

  8. CRADA Final Report for CRADA Number NFE-10-02991 "Development and Commercialization of Alternative Carbon Precursors and Conversion Technologies"

    Energy Technology Data Exchange (ETDEWEB)

    Norris, Rober [ORNL; Paulauskas, Felix [ORNL; Naskar, Amit [ORNL; Kaufman, Michael [ORNL; Yarborough, Ken [ORNL; Derstine, Chris [The Dow Chemical Company

    2013-10-01

    The overall objective of the collaborative research performed by the Oak Ridge National Laboratory (ORNL) and the Dow Chemical Company under this Cooperative Research And Development Agreement (CRADA NFE-10-02991) was to develop and establish pathways to commercialize new carbon fiber precursor and conversion technology. This technology is to produce alternative polymer fiber precursor formulations as well as scaled energy-efficient advanced conversion technology to enable continuous mode conversion to obtain carbonized fibers that are technically and economically viable in industrial markets such as transportation, wind energy, infrastructure and oil drilling applications. There have been efforts in the past to produce a low cost carbon fiber. These attempts have to be interpreted against the backdrop of the market needs at the time, which were strictly military aircraft and high-end aerospace components. In fact, manufacturing costs have been reduced from those days to current practice, where both process optimization and volume production have enabled carbon fiber to become available at prices below $20/lb. However, the requirements of the lucrative aerospace market limits further price reductions from current practice. This approach is different because specific industrial applications are targeted, most specifically wind turbine blade and light vehicle transportation, where aircraft grade carbon fiber is not required. As a result, researchers are free to adjust both manufacturing process and precursor chemistry to meet the relaxed physical specifications at a lower cost. This report documents the approach and findings of this cooperative research in alternative precursors and advanced conversion for production of cost-effective carbon fiber for energy missions. Due to export control, proprietary restrictions, and CRADA protected data considerations, specific design details and processing parameters are not included in this report.

  9. Three-dimensional thermal simulations of thin solid carbon foils for charge stripping of high current uranium ion beams at a proposed new heavy-ion linac at GSI

    Science.gov (United States)

    Tahir, N. A.; Kim, V.; Schlitt, B.; Barth, W.; Groening, L.; Lomonosov, I. V.; Piriz, A. R.; Stöhlker, Th.; Vormann, H.

    2014-04-01

    This paper presents an extensive numerical study of heating of thin solid carbon foils by 1.4 MeV/u uranium ion beams to explore the possibility of using such a target as a charge stripper at the proposed new Gesellschaft für Schwerionenforschung high energy heavy-ion linac. These simulations have been carried out using a sophisticated 3D computer code that accounts for physical phenomena that are important in this problem. A variety of beam and target parameters have been considered. The results suggest that within the considered parameter range, the target will be severely damaged by the beam. Thus, a carbon foil stripper does not seem to be a reliable option for the future Gesellschaft für Schwerionenforschung high energy heavy-ion linac, in particular, at FAIR design beam intensities.

  10. The present status of carbon 14 analysis and projects for beryllium 10 analysis at the Tandetron 1 accelerator, Nagoya University

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Toshio; Oda, Hirotaka; Ikeda, Akiko; Niu, Etsuko [Nagoya Univ. (Japan)

    2001-02-01

    The operation experience in 1999 of the Tandetron accelerator age estimation system, Nagoya University, is reported, after the overview and the history of the accelerator is briefly described. Total number of carbon 14 environmental samples analyzed was 8567. The project of introducing new HVEE Tandetron for C-14 analysis, and modifying the present GIC Tandetron for Be-10 analysis is presented. Ion source shall be replaced, and the heavy ion detector shall be installed. Projected geological and archaeological studies using Be-10 are enumerated. (A. Yamamoto)

  11. Electron-Beam Irradiation Effect on Thermal and Mechanical Properties of Nylon-6 Nanocomposite Fibers Infused with Diamond and Diamond Coated Carbon Nanotubes

    Science.gov (United States)

    Imam, Muhammad A.; Jeelani, Shaik; Rangari, Vijaya K.; Gome, Michelle G.; Moura, Esperidiana. A. B.

    2016-02-01

    Nylon-6 is an engineering plastic with excellent properties and processability, which are essential in several industrial applications. The addition of filler such as diamond (DN) and diamond coated carbon nanotubes (CNTs) to form molded composites may increase the range of Nylon-6 applications due to the resulting increase in strength. The effects of electron-beam irradiation on these thermoplastic nanocomposites are either increase in the cross-linking or causes chain scission. In this study, DN-coated CNTs were synthesized using the sonochemical technique in the presence of cationic surfactant cetyltrimethyl ammonium bromide (CTAB). The DN-coated CNTs nanoparticles and diamond nanoparticles were then introduced into Nylon-6 polymer through a melt extrusion process to form nanocomposite fibers. They were further tested for their mechanical (Tensile) and thermal properties (thermogravimetric analysis (TGA), differential scanning calorimetry (DSC)). These composites were further exposed to the electron-beam (160kGy, 132kGy and 99kGy) irradiation using a 1.5MeV electron-beam accelerator, at room temperature, in the presence of air and tested for their thermal and mechanical properties. The best ultimate tensile strength was found to be 690MPa and 864MPa irradiated at 132 for DN/CNTs/Nylon-6 and Diamond/Nylon-6 nanocomposite fiber as compared to 346MPa and 321MPa for DN/CNTs/Nylon-6 and Diamond/Nylon-6 nanocomposite fiber without irradiation. The neat Nylon-6 tensile strength was 240MPa. These results are consistent with the activation energy calculated from TGA graphs. DSC analysis result shows that the slight increase in glass transition temperature (Tg) and decrease in melting temperature (Tm) which was expected from high electron-beam radiation dose.

  12. MODIFICATION OF CARBON STEEL BY LASER SURFACE MELTING: PART II: EFFECT OF LASER BEAM POWER ON MICROSTRUCTURAL FEATURES AND SURFACE HARDNESS

    Directory of Open Access Journals (Sweden)

    Hashem F. El-Labban

    2013-01-01

    Full Text Available The surface hardness has an important effect on the wear resistance of different materials. The present study aims to improve the surface hardness of carbon steel through the application of laser surface melting with suitable conditions. The laser beam power and travelling speed are the main factors that affect the properties of the treated zone. In this study, three different conditions of laser beam power (1800, 1500 and 1200 W at fixed travelling speed of 1000 mm min-1 were chosen to study the effect of laser beam power. The resulted laser treated specimens were investigated in macro and microscopically scale using optical and scanning electron microscope. Hardness measurements were also carried out through the thickness of the laser treated zones. The laser treated areas with all used powers results in melted and solidified zone on the surface of the steel. The laser power of 1800 W results in the deepest value of the laser treated zone (about 1.7 mm. Moreover, by increasing the laser power, the width of the treated zone was slightly increases. At areas near the free surface, large martensite plates were observed in higher laser power (1800 W, while longer acicular martensite was observed in lower laser power (1200 W. For laser power of 1800 W, the bainite structures in ferrite grains were more pronounced in larger areas and in closer areas to the free surface. On the other hand, the lower laser power shows higher hardness on the free surface than that of higher power. The sizes of Heat Affect Zone (HAZ areas were increased by increasing the laser beam power. In all conditions, the heat affected zone areas were composed of partially decomposed pearlite in ferrite grains.

  13. Synthesis and biological evaluation of carbon-11 and fluorine-18 labeled tracers for in vivo visualization of PDE10A

    International Nuclear Information System (INIS)

    Introduction: In vivo visualization of PDE10A using PET provides a tool to evaluate the role of PDE10A in various neuropsychiatric diseases and can also be useful in the clinical evaluation of PDE10A inhibitor drug candidates. We evaluated several carbon-11 and fluorine-18 labeled PDE10A inhibitors as potential PDE10A PET radioligands. Materials and Methods: [11C]MP10, [11C]JNJ42071965 and four other tracers were developed. Their biodistribution was evaluated in rats. Rat plasma and brain radiometabolites were quantified. Baseline microPET imaging was performed in normal rats and PDE10A knockout (KO) and wild-type (WT) mice. Blocking and displacement studies were conducted. The selectivity of the tracer binding was further studied in an ex vivo autoradiography experiment in PDE10A KO and WT mice. Results: Biodistribution showed brain uptake for all tracers in the striatum and wash-out from the cerebellum. [11C]1 (11C-MP10) had the highest specific uptake index (striatum (S) vs. cerebellum (C) ratios (S/C)-1) at 60 min (7.4). [11C]5 ([11C]JNJ42071965) had a high index at the early time points (1.0 and 3.7 at 2 and 30 min p.i., respectively). The affinity of [11C]4, [18 F]3 and [18 F]6 was too low to visualize PDE10A using microPET. [11C] 2 showed a specific binding, while kinetics of [11C]1 were too slow. [11C]5 reached equilibrium after 10 min (uptake index = 1.2). Blocking and displacement experiments in rats and baseline imaging in PDE10A KO mice showed specific and reversible binding of [11C]5 to PDE10A. Conclusions: We successfully radiolabeled and evaluated six radiotracers for their potential to visualize PDE10A in vivo. While [11C]1 had the highest striatal specific uptake index, its slow kinetics likely compromise clinical use of this tracer. [11C]5 has a relatively high striatum-to-background ratio and fast kinetic profile, which makes it a valuable carbon-11 alternative

  14. Radiocarbon-based source apportionment of black carbon (BC) in PM 10 aerosols from residential area of suburban Tokyo

    Science.gov (United States)

    Uchida, Masao; Kumata, Hidetoshi; Koike, Yasuyo; Tsuzuki, Mikio; Uchida, Tatsuya; Fujiwara, Kitao; Shibata, Yasuyuki

    2010-04-01

    The AMS technique was applied to analyse black carbon (BC), total organic carbon (TOC), and previously reported polycyclic aromatic hydrocarbons (PAHs) in PM 10 aerosols from a residential area, suburban Tokyo, to determine natural abundance of radiocarbon ( 14C), an ideal tracer to distinguish fossil fuel ( 14C-free) from modern biomass combustion sources of pyrolytic products. The 14C concentrations in BC, isolated using the CTO-375 method, were 42% and 30% pMC (in terms of percent Modern Carbon: pMC) in summer and winter, respectively. The 14C concentrations in BC were also compared with those of compound-class specific 14C content of PAHs previously reported for the same samples: they were 45% and 33% pMC in summer and winter, respectively. The 14C signals of BC were identical to those of high molecular weight (MW ⩾ 226, 5-6 rings) PAHs. The resemblance between 14C signals of BC and PAHs can be referred as a 'certificate' for the validity of the BC isolation method employed in this study. Also, it suggests that 14C-BC approach can be a surrogate for PAHs specific 14C analyses to monitor seasonal source variation of combustion-derived pyrolytic products. On the other hand, 14C contents of total organic carbon in 2004 were 61% and 42% pMC in summer and winter, respectively. This is likely attributed to higher contribution of plant activity in summer.

  15. Three ways to solve the orbit of KIC 11 558 725: a 10-day beaming sdB+WD binary with a pulsating subdwarf

    Science.gov (United States)

    Telting, J. H.; Østensen, R. H.; Baran, A. S.; Bloemen, S.; Reed, M. D.; Oreiro, R.; Farris, L.; Ottosen, T. A.; Aerts, C.; Kawaler, S. D.; Heber, U.; Prins, S.; Green, E. M.; Kalomeni, B.; O'Toole, S. J.; Mullally, F.; Sanderfer, D. T.; Smith, J. C.; Kjeldsen, H.

    2012-08-01

    The recently discovered subdwarf B (sdB) pulsator KIC 11 558 725 is one of the 16 pulsating sdB stars detected in the Kepler field. It features a rich g-mode frequency spectrum, with a few low-amplitude p-modes at short periods. This makes it a promising target for a seismic study aiming to constrain the internal structure of this star, and of sdB stars ingeneral. We have obtained ground-based spectroscopic radial-velocity measurements of KIC 11 558 725 based on low-resolution spectra in the Balmer-line region, spanning the 2010 and 2011 observing seasons. From these data we have discovered that KIC 11 558 725 is a binary with period P = 10.05 d, and that the radial-velocity amplitude of the sdB star is 58 km s-1. Consequently the companion of the sdB star has a minimum mass of 0.63 M⊙, and is therefore most likely an unseen white dwarf. We analyse the near-continuous 2010-2011 Kepler light curve to reveal the orbital Doppler-beaming effect, giving rise to light variations at the 238 ppm level, which is consistent with the observed spectroscopic orbital radial-velocity amplitude of the subdwarf. We use the strongest 70 pulsation frequencies in the Kepler light curve of the subdwarf as clocks to derive a third consistent measurement of the orbital radial-velocity amplitude, from the orbital light-travel delay. The orbital radius asdBsini = 11.5 R⊙ gives rise to a light-travel time delay of 53.6 s, which causes aliasing and lowers the amplitudes of the shortest pulsation frequencies, unless the effect is corrected for. We use our high signal-to-noise average spectra to study the atmospheric parameters of the sdB star, deriving Teff = 27 910 K andlog g = 5.41 dex, and find that carbon, nitrogen and oxygen are underabundant relative to the solar mixture. Furthermore, we analyse the Kepler light curve for its pulsational content and extract more than 160 significant frequencies.We investigate the pulsation frequencies for expected period spacings and rotational

  16. Design and Analysis Methodologies for Inflated Beams

    NARCIS (Netherlands)

    Veldman, S.L.

    2005-01-01

    The central theme of the thesis is bending behaviour of inflated beams. Three different types of beams have been analysed for the bending load case: a straight cylindrical beam made of anisotropic foil material, a conical beam made of an isotropic foil material, and a carbon fibre braided beam. The

  17. Output factor comparison of Monte Carlo and measurement for Varian TrueBeam 6 MV and 10 MV flattening filter-free stereotactic radiosurgery system.

    Science.gov (United States)

    Cheng, Jason Y; Ning, Holly; Arora, Barbara C; Zhuge, Ying; Miller, Robert W

    2016-01-01

    The dose measurements of the small field sizes, such as conical collimators used in stereotactic radiosurgery (SRS), are a significant challenge due to many factors including source occlusion, detector size limitation, and lack of lateral electronic equilibrium. One useful tool in dealing with the small field effect is Monte Carlo (MC) simulation. In this study, we report a comparison of Monte Carlo simulations and measurements of output factors for the Varian SRS system with conical collimators for energies of 6 MV flattening filter-free (6 MV) and 10 MV flattening filter-free (10 MV) on the TrueBeam accelerator. Monte Carlo simulations of Varian's SRS system for 6 MV and 10 MV photon energies with cones sizes of 17.5 mm, 15.0 mm, 12.5 mm, 10.0 mm, 7.5 mm, 5.0 mm, and 4.0 mm were performed using EGSnrc (release V4 2.4.0) codes. Varian's version-2 phase-space files for 6 MV and 10 MV of TrueBeam accelerator were utilized in the Monte Carlo simulations. Two small diode detectors Edge (Sun Nuclear) and Small Field Detector (SFD) (IBA Dosimetry) were applied to measure the output factors. Significant errors may result if detector correction factors are not applied to small field dosimetric measurements. Although it lacked the machine-specific kfclin,fmsrQclin,Qmsr correction factors for diode detectors in this study, correction factors were applied utilizing published studies conducted under similar conditions. For cone diameters greater than or equal to 12.5 mm, the differences between output factors for the Edge detector, SFD detector, and MC simulations are within 3.0% for both energies. For cone diameters below 12.5 mm, output factors differences exhibit greater variations. PMID:27167266

  18. The T10 beam produces a few hits per event. In ALICE the SSD will have to cope with many hits per strip. In the three centimeters of aluminium the beam will produce many secondary particles. This increases the chance of multiple hits per strip, although not to the level in ALICE.

    CERN Multimedia

    Nooren, G.

    2004-01-01

    The T10 beam produces a few hits per event. In ALICE the SSD will have to cope with many hits per strip. In the three centimeters of aluminium the beam will produce many secondary particles. This increases the chance of multiple hits per strip, although not to the level in ALICE.

  19. Nuclear fragmentation of high-energy light-ion beams in water

    International Nuclear Information System (INIS)

    Light-ion beams ranging between carbon and neon with energies of a few hundred MeV/u offer favorable conditions for the treatment of deep-seated tumors. Nuclear fragmentation experiments are presented to study favorable therapy beams simultaneously in thick water target. Comparative measurements with 10B, 12C, 14N, 16O beams are described. (R.P.) 5 refs.; 4 figs

  20. The beam energy calibration system for the BEPC-II collider

    CERN Document Server

    Achasov, M N; Mo, Xiaohu; Muchnoi, N Yu; Qin, Qing; Qu, Huamin; Wang, Yifang; Xu, Jinqiang

    2008-01-01

    This document contains a proposal of the BEPC-II collider beam energy calibration system (IHEP, Beijing). The system is based on Compton backscattering of carbon dioxide laser radiation, producing a beam of high energy photons. Their energy spectrum is then accurately measured by HPGe detector. The high-energy spectrum edge will allow to determine the average electron or positron beam energy with relative accuracy about 3x10^-5.

  1. Synergistic effect of heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin and X-rays, but not carbon-ion beams, on lethality in human oral squamous cell carcinoma cells

    International Nuclear Information System (INIS)

    The purpose of this study is to clarify the effect of a heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin (17-AAG), in combination with X-rays or carbon-ion beams on cell killing in human oral squamous cell carcinoma LMF4 cells. Cell survival was measured by colony formation assay. Cell-cycle distribution was analyzed by flow cytometry. Expression of DNA repair-related proteins was investigated by western blotting. The results showed 17-AAG to have synergistic effects on cell lethality with X-rays, but not with carbon-ion beams. The 17-AAG decreased G2/M arrest induced by X-rays, but not by carbon-ion beams. Both X-ray and carbon-ion irradiation up-regulated expression of non-homologous end-joining-associated proteins, Ku70 and Ku80, but 17-AAG inhibited only X-ray-induced up-regulation of these proteins. These results show that 17-AAG with X-rays releases G2/M phase arrest; cells carrying misrepaired DNA damage then move on to the G1 phase. We demonstrate, for the first time, that the radiosensitization effect of 17-AAG is not seen with carbon-ion beams because 17-AAG does not affect these changes. (author)

  2. Electroporative interleukin-10 gene transfer ameliorates carbon tetrachloride-induced murine liver fibrosis by MMP and TIMP modulation

    Institute of Scientific and Technical Information of China (English)

    Wen-ying CHOU; Cheng-nan LU; Tsung-hsing LEE; Chia-ling WU; Kung-sheng HUNG; Allan M CONCEJERO; Bruno JAWAN; Cheng-haung WANG

    2006-01-01

    Aim:Liver fibrosis represents a process of healing and scarring in response to chronic liver injury.Effective therapies for liver fibrosis are lacking.Interleukin-10 (IL-10) is a cytokine that downregulates pro-inflammatory responses and has a modulatory effect on hepatic fibrogenesis.The aim of this study was to investigate whether electroporative IL-10 gene therapy has an hepatic fibrolytic effect on mice.Methods:Hepatic fibrosis was induced by administering carbon tetrachloride (CCl4) for 10 weeks in mice.The human IL-10 expression plasmid was delivered via electroporation after hepatic fibrosis was established.Histopathology,reverse transcription polymerase chain reaction (RT-PCR) ,immunoblotting,and gelatin zymography were used to investigate the possible mechanisms of action of IL-10.Results:Human IL-10 gene therapy reversed CCl4-induced liver fibrosis in mice.RT-PCR revealed that IL-10 gene therapy attenuated liver TGF-β1,collagen αl,fibronectin,and cell adhesion molecule mRNA upregulation.Following gene transfer,both the activation of α-smooth muscle actin and cyclooxygenase-2 were significantly attenuated.Furthermore.IL-10 significantly inhibited matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of matrix metalloproteinase (TIMP) activation after CCl4 intoxication.Conclusions:We demonstrated that IL-10 gene therapy attenuated CCl4-induced liver fibrosis in mice.IL-10 prevented upregulated fibrogenic and pro-inflammatory gene responses.Its collagenolytic effect may be attributed to MMP and TIMP modulation.IL-10 gene therapy may be an effective therapeutic modality against liver fibrosis with potential clinical use.

  3. Voltammetric Detection of Diquat at the Carbon Paste Electrode Containing a Ca10(PO46(OH2

    Directory of Open Access Journals (Sweden)

    Moulay Abderrahim EL MHAMMEDI

    2007-01-01

    Full Text Available We report a sensitive electrochemical voltammetric method for analyzing diquat (DQ ions using a carbon paste electrochemical (CPE modified by porous material, such as hydroxyapatite (HAP. Diquat strongly adsorbed on a HAP-CPE surface and provides facile electrochemical quantitative methods for electroactive DQ ions. Operational parameters have been optimized, and the stripping voltammetric performance has been studied using square wave voltammetry. The peaks current intensity are highly linear over the 7×10-7–3×10-4 mol L-1 diquat range examined (10-min accumulation time, with a good sensitivity. These findings can lead to a widespread use of electrochemical sensors to detect DQ contaminates.Scanning electron microscopy was used for morphology observation and in particular the X-ray diffraction analysis (XRD and Fourier transformed infrared spectroscopy (FTIR analysis for characterization of synthesis powder.

  4. Thick-target neutron, gamma-ray, and radionuclide production for protons below 12 MeV on nickel and carbon beam-stops

    Energy Technology Data Exchange (ETDEWEB)

    Chadwick, M.B.; Young, P.G.; Wilson, W.B.

    1998-03-01

    Nuclear model calculations using the GNASH code are described for protons below 12 MeV incident on nickel and carbon isotopes, for beam stop design in the Los Alamos Accelerator Production of Tritium Low Energy Demonstration Accelerator (LEDA) project. The GNASH calculations apply Hauser-Feshbach and preequilibrium reaction theories and can make use of pre-calculated direct reaction cross sections to low-lying residual nucleus states. From calculated thin target cross sections, thick target 6.7 MeV and 12 MeV proton-induced production of neutrons, gamma rays, and radionuclides are determined. Emission spectra of the secondary neutrons and gamma rays are also determined. The model calculations are validated through comparisons with experimental thin- and thick-target measurements. The results of this work are being utilized as source terms in MCNP analyses for LEDA.

  5. A study of V79 cell survival after for proton and carbon ion beams as represented by the parameters of Katz' track structure model

    DEFF Research Database (Denmark)

    Grzanka, Leszek; Waligórski, M. P. R.; Bassler, Niels

    Katz’s theory of cellular track structure (1) is an amorphous analytical model which applies a set of four cellular parameters representing survival of a given cell line after ion irradiation. Usually the values of these parameters are best fitted to a full set of experimentally measured survival...... curves available for a variety of ions. Once fitted, using these parameter values and the analytical formulae of the model calculations, cellular survival curves and RBE may be predicted for that cell line after irradiation by any ion, including mixed ion fields. While it is known that the Katz model...... carbon irradiation. 1. Katz, R., Track structure in radiobiology and in radiation detection. Nuclear Track Detection 2: 1-28 (1978). 2. Furusawa Y. et al. Inactivation of aerobic and hypoxic cells from three different cell lines by accelerated 3He-, 12C- and 20Ne beams. Radiat Res. 2012 Jan; 177...

  6. An integrated Dissolved Organic Carbon Dynamics Model (DOCDM 1.0): model development and a case study in the Alaskan Yukon River Basin

    OpenAIRE

    Lu, X.; Zhuang, Q.

    2015-01-01

    Quantitative understanding of the variation in dissolved organic carbon (DOC) is important to studying the terrestrial ecosystem carbon cycle. This study presents a process-based, dissolved organic carbon dynamics model (DOCDM 1.0) that couples the soil heat conduction, water flow, DOC production, mineralization and transport in both surface and subsurface of soil profile to quantify DOC dynamics in boreal terrestrial ecosystems. The model...

  7. Improved recovery demonstration for Williston Basin carbonates. Annual report, June 10, 1995--June 9, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Carrell, L.A.; Sippel, M.A.

    1996-09-01

    The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in-place, methods for improved completion efficiency and the suitability of waterflooding in Red River and Ratcliffe shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing three-dimensional and multi-component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with extended-reach jetting lance and other ultra-short-radius lateral technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil in place will result in additional oil recovery by primary and enhanced recovery processes.

  8. Low current beam techniques

    Energy Technology Data Exchange (ETDEWEB)

    Saint, A.; Laird, J.S.; Bardos, R.A.; Legge, G.J.F. [Melbourne Univ., Parkville, VIC (Australia). School of Physics; Nishijima, T.; Sekiguchi, H. [Electrotechnical Laboratory, Tsukuba (Japan).

    1993-12-31

    Since the development of Scanning Transmission Microscopy (STIM) imaging in 1983 many low current beam techniques have been developed for the scanning (ion) microprobe. These include STIM tomography, Ion Beam Induced Current, Ion Beam Micromachining and Microlithography and Ionoluminense. Most of these techniques utilise beam currents of 10{sup -15} A down to single ions controlled by beam switching techniques This paper will discuss some of the low beam current techniques mentioned above, and indicate, some of their recent applications at MARC. A new STIM technique will be introduced that can be used to obtain Z-contrast with STIM resolution. 4 refs., 3 figs.

  9. The Bonding of NO2, NH3, and CH2NY to Models of a (10,0) Carbon Nanotube

    Science.gov (United States)

    Walch, Stephen P.

    2004-01-01

    We have studied the bonding of NO2, NH3, and CH2NH to a (10,O) carbon nanotube using the MP2 and ONIOM methods with extended basis sets. We find bond strengths of 3.5, 3.6. and 6.3 kcal/mol for NO2, NH3, and CH2NH, respectively, using the ONIOM method with the high accuracy part treated at the MP2/aug-CC-pVTZ level and the remainder of the CNT approximated at the UFF level and including an estimate of basis set superposition error using the counterpoise method.

  10. Under-response of a PTW-60019 microDiamond detector in the Bragg peak of a 62 MeV/n carbon ion beam

    Science.gov (United States)

    Rossomme, S.; Hopfgartner, J.; Vynckier, S.; Palmans, H.

    2016-06-01

    To investigate the linear energy transfer (LET) dependence of the response of a PTW-60019 Freiburg microDiamond detector, its response was compared to the response of a plane-parallel Markus chamber in a 62 MeV/n mono-energetic carbon ion beam. Results obtained with two different experimental setups are in agreement. As recommended by IAEA TRS-398, the response of the Markus chamber was corrected for temperature, pressure, polarity effects and ion recombination. No correction was applied to the response of the microDiamond detector. The ratio of the response of the Markus chamber to the response of the microDiamond is close to unity in the plateau region. In the Bragg peak region, a significant increase of the ratio is observed, which increases to 1.2 in the distal edge region. Results indicate a correlation between the under-response of the microDiamond detector and high LET values. The combined relative standard uncertainty of the results is estimated to be 2.38% in the plateau region and 12% in the distal edge region. These values are dominated by the uncertainty of alignment in the non-uniform beam and the uncertainty of range determination.

  11. Under-response of a PTW-60019 microDiamond detector in the Bragg peak of a 62 MeV/n carbon ion beam.

    Science.gov (United States)

    Rossomme, S; Hopfgartner, J; Vynckier, S; Palmans, H

    2016-06-21

    To investigate the linear energy transfer (LET) dependence of the response of a PTW-60019 Freiburg microDiamond detector, its response was compared to the response of a plane-parallel Markus chamber in a 62 MeV/n mono-energetic carbon ion beam. Results obtained with two different experimental setups are in agreement. As recommended by IAEA TRS-398, the response of the Markus chamber was corrected for temperature, pressure, polarity effects and ion recombination. No correction was applied to the response of the microDiamond detector. The ratio of the response of the Markus chamber to the response of the microDiamond is close to unity in the plateau region. In the Bragg peak region, a significant increase of the ratio is observed, which increases to 1.2 in the distal edge region. Results indicate a correlation between the under-response of the microDiamond detector and high LET values. The combined relative standard uncertainty of the results is estimated to be 2.38% in the plateau region and 12% in the distal edge region. These values are dominated by the uncertainty of alignment in the non-uniform beam and the uncertainty of range determination. PMID:27224547

  12. Measurement of neutron spectra generated by a 62 AMeV carbon-ion beam on a PMMA phantom using extended range Bonner sphere spectrometers

    Science.gov (United States)

    Bedogni, R.; Amgarou, K.; Domingo, C.; Russo, S.; Cirrone, G. A. P.; Pelliccioni, M.; Esposito, A.; Pola, A.; Introini, M. V.; Gentile, A.

    2012-07-01

    Neutrons constitute an important component of the radiation environment in hadron therapy accelerators. Their energy distribution may span from thermal up to hundred of MeV. The characterization of these fields in terms of dosimetric or spectrometric quantities is crucial for either the patient protection or the facility design aspects. To date, the Extended Range Bonner Sphere Spectrometer (ERBSS) is the only instrument able to simultaneously determine all spectral components in such workplaces. With the aim of providing useful data to the scientific community involved in neutron measurements at hadron therapy facilities, a measurement campaign was carried out at the Centro di AdroTerapia e Applicazioni Nucleari Avanzate (CATANA) of INFN-LNS (Laboratori Nazionali del Sud), where a 62 AMeV carbon ion is available. The beam was directed towards a PMMA phantom, simulating the patient, and two neutron measurement points were established at 0° and 90° with respect to the beam-line. The ERBSSs of UAB (Universidad Autónoma de Barcelona-Grup de Física de les Radiacions) and INFN (Istituto Nazionale di Fisica Nucleare-Laboratori Nazionali di Frascati) were used to measure the resulting neutron fields. The two ERBSSs use different detectors and sphere diameters, and have been independently calibrated. The FRUIT code was used to unfold the results.

  13. SEM in situ MiniCantilever Beam Bending of U-10Mo/Zr/Al Fuel Elements

    Energy Technology Data Exchange (ETDEWEB)

    Mook, William [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Baldwin, Jon K. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Martinez, Ricardo M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mara, Nathan A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-06-16

    In this work, the fracture behavior of Al/Zr and Zr/dU-10Mo interfaces was measured via the minicantilever bend technique. The energy dissipation rates were found to be approximately 3.7-5 mj/mm2 and 5.9 mj/mm2 for each interface, respectively. It was found that in order to test the Zr/U-10Mo interface, location of the hinge of the cantilever was a key parameter. While this test could be adapted to hot cell use through careful alignment fixturing and measurement of crack lengths with an optical microscope (as opposed to SEM, which was used here out of convenience), machining of the cantilevers via MiniMill in such a way as to locate the interfaces at the cantilever hinge, as well as proper placement of a femtosecond laser notch will continue to be key challenges in a hot cell environment.

  14. Muon Beam at the Fermilab Test Beam Area

    OpenAIRE

    Denisov, Dmitri; Evdokimov, Valery; Lukić, Strahinja; Ujić, Predrag

    2016-01-01

    The intensities and profiles of the muon beam behind the beam dump of the Fermilab test beam area when the facility is running in the "pion" beam mode are measured and summarized in this note. This muon beam with momenta in the range 10 - 50 GeV/c provides an opportunity to perform various measurements in parallel with other users of the test beam area.

  15. 1 1/2 years of experience with a 10 MeV self-shielded on-line e-beam sterilization system

    International Nuclear Information System (INIS)

    The Vascular Intervening Group of the Guidant Corporation (Guidant IV) has been operating a self-shielded, 10 MeV 4 kW, electron beam sterilization system since July of 1988. The system was designed, built and installed in a 70 square meter area in an existing Guidant manufacturing facility by Titan Scan Corporation and performance of the system was validated in conformance with 1S0-11137 standards. The goal of this on-site e-beam system was 'just in time' JIT, sterilization, i.e. the ability to manufacture, sterilize and ship, high intrinsic value medical devices in less than 24 hours. The benefits of moving from a long gas sterilization cycle of greater than one week to a JIT process were envisioned to be a) speed to market with innovated new products b) rapid response to customer requirements c) reduced inventory carrying costs and finally manufacturing and quality system efficiency. The ability of Guidant to realize these benefits depended upon the ability of the Guidant VI business units to adapt to the new sterilization modality and functionality and on the overall system reliability. This paper reviews the operating experience to date and the overall system reliability. (author)

  16. ATA diagnostic beam dump conceptual design

    International Nuclear Information System (INIS)

    A diagnostic beam dump, able to withstand 72,000 pulses (10 kA, 50 MeV/pulse) per shift was designed and analyzed. The analysis shows that the conceptual beam dump design consisting of 80 vitreous carbon plate-foam elements is able to withstand the thermal and mechanical stresses generated. X-rays produced by bremsstrahlung are absorbed by a three element copper plate-foam x-ray absorber. Cooling between bursts of electron pulses is provided by pressurized helium

  17. OZONE REACTION WITH N-ALDEHYDES (N=4-10), BENZALDEHYDE, ETHANOL, ISOPROPANOL, AND N-PROPANOL ADSORBED ON A DUAL-BED GRAPHITIZED CARBON/CARBON MOLECULAR SIEVE ADSORBENT CARTRIDGE

    Science.gov (United States)

    Ozone reacts with n-aldehydes (n = 4 - 10), benzaldehyde, ethanol, isopropanol, and n-propanol adsorbed on a dual-bed graphitized carbon/carbon molecular sieve adsorbent cartridge. Destruction of n-aldehydes increases with n number and with ozone concentration. In some samp...

  18. MODIFICATION OF CARBON STEEL BY LASER SURFACE MELTING: PART I: EFFECT OF LASER BEAM TRAVELLING SPEED ON MICROSTRUCTURAL FEATURES AND SURFACE HARDNESS

    Directory of Open Access Journals (Sweden)

    Hashem F. El-Labban

    2013-01-01

    Full Text Available The present study aims to improve the surface hardness of carbon steel by application of laser surface melting of effective conditions. The travelling speed of laser beam during this treatment is one of the important treatment conditions. This study aims to investigate the effect of laser surface melting with different beam speeds on macro and microstructure as well as the hardness distribution through the thickness of carbon steel. To achieve this target, three different travelling speeds (1500, 1000 and 500 mm min-1 at a constant beam power of 800 W were chosen in this study. The resulted laser treated specimens were investigated in macro and microscopically scale using optical and scanning electron microscope. Hardness measurements were also carried out through the thickness of the laser treated specimens. The laser treated areas with all used travelling speeds results in melted and solidified zone on the surface of the steel. In the same time, Plates of acicular martensite structure were observed within the upper part of the melted and solidified zone in almost all experimental conditions, while some bainite structure in ferrite grains are detected in its lower part. By increasing the travelling speed, the depth of the laser treated zone was decreases, while travelling speed has much less significant effect on the laser treated zone width. The size of the formed martensite plates was increased by decreasing the travelling speed from 1500 to 500 mm min-1. On the other hand, the travelling speed has a straight effect on the length of the acicular martensite; as the travelling speed increases, the acicular martensite became longer, while it shows fine acicular martensite at lower travelling speeds. The depth that full martensite structure can be reached is increased by increasing travelling speed. At lower travelling speed (500 mm min-1, large amount of bainite structure is observed at the center of the treated zone up to its lower end. The

  19. Induced radioactivity of a GSO scintillator by secondary fragments in carbon ion therapy and its effects on in-beam OpenPET imaging.

    Science.gov (United States)

    Hirano, Yoshiyuki; Nitta, Munetaka; Nishikido, Fumihiko; Yoshida, Eiji; Inadama, Naoko; Yamaya, Taiga

    2016-07-01

    The accumulation of induced radioactivity within in-beam PET scanner scintillators is of concern for its long-term clinical usage in particle therapy. To estimate the effects on OpenPET which we are developing for in-beam PET based on GSOZ (Zi doped Gd2SiO5), we measured the induced radioactivity of GSO activated by secondary fragments in a water phantom irradiation by a (12)C beam with an energy of 290 MeV u(-1). Radioisotopes of Na, Ce, Eu, Gd, Nd, Pm and Tb including positron emitters were observed in the gamma ray spectra of the activated GSO with a high purity Ge detector and their absolute radioactivities were calculated. We used the Monte Carlo simulation platform, Geant4 in which the observed radioactivity was assigned to the scintillators of a precisely reproduced OpenPET and the single and coincidence rates immediately after one treatment and after one-year usage were estimated for the most severe conditions. Comparing the highest coincidence rate originating from the activated scintillators (background) and the expected coincidence rate from an imaging object (signal), we determined the expected signal-to-noise ratio to be more than 7 within 3 min and more than 10 within 1 min from the scan start time. We concluded the effects of scintillator activation and their accumulation on the OpenPET imaging were small and clinical long-term usage of the OpenPET was feasible.

  20. Induced radioactivity of a GSO scintillator by secondary fragments in carbon ion therapy and its effects on in-beam OpenPET imaging.

    Science.gov (United States)

    Hirano, Yoshiyuki; Nitta, Munetaka; Nishikido, Fumihiko; Yoshida, Eiji; Inadama, Naoko; Yamaya, Taiga

    2016-07-01

    The accumulation of induced radioactivity within in-beam PET scanner scintillators is of concern for its long-term clinical usage in particle therapy. To estimate the effects on OpenPET which we are developing for in-beam PET based on GSOZ (Zi doped Gd2SiO5), we measured the induced radioactivity of GSO activated by secondary fragments in a water phantom irradiation by a (12)C beam with an energy of 290 MeV u(-1). Radioisotopes of Na, Ce, Eu, Gd, Nd, Pm and Tb including positron emitters were observed in the gamma ray spectra of the activated GSO with a high purity Ge detector and their absolute radioactivities were calculated. We used the Monte Carlo simulation platform, Geant4 in which the observed radioactivity was assigned to the scintillators of a precisely reproduced OpenPET and the single and coincidence rates immediately after one treatment and after one-year usage were estimated for the most severe conditions. Comparing the highest coincidence rate originating from the activated scintillators (background) and the expected coincidence rate from an imaging object (signal), we determined the expected signal-to-noise ratio to be more than 7 within 3 min and more than 10 within 1 min from the scan start time. We concluded the effects of scintillator activation and their accumulation on the OpenPET imaging were small and clinical long-term usage of the OpenPET was feasible. PMID:27280308

  1. Induced radioactivity of a GSO scintillator by secondary fragments in carbon ion therapy and its effects on in-beam OpenPET imaging

    Science.gov (United States)

    Hirano, Yoshiyuki; Nitta, Munetaka; Nishikido, Fumihiko; Yoshida, Eiji; Inadama, Naoko; Yamaya, Taiga

    2016-07-01

    The accumulation of induced radioactivity within in-beam PET scanner scintillators is of concern for its long-term clinical usage in particle therapy. To estimate the effects on OpenPET which we are developing for in-beam PET based on GSOZ (Zi doped Gd2SiO5), we measured the induced radioactivity of GSO activated by secondary fragments in a water phantom irradiation by a 12C beam with an energy of 290 MeV u‑1. Radioisotopes of Na, Ce, Eu, Gd, Nd, Pm and Tb including positron emitters were observed in the gamma ray spectra of the activated GSO with a high purity Ge detector and their absolute radioactivities were calculated. We used the Monte Carlo simulation platform, Geant4 in which the observed radioactivity was assigned to the scintillators of a precisely reproduced OpenPET and the single and coincidence rates immediately after one treatment and after one-year usage were estimated for the most severe conditions. Comparing the highest coincidence rate originating from the activated scintillators (background) and the expected coincidence rate from an imaging object (signal), we determined the expected signal-to-noise ratio to be more than 7 within 3 min and more than 10 within 1 min from the scan start time. We concluded the effects of scintillator activation and their accumulation on the OpenPET imaging were small and clinical long-term usage of the OpenPET was feasible.

  2. Carbon Nanotube Container: Complexes of C50H10 with Small Molecules.

    Science.gov (United States)

    Dodziuk, Helena; Korona, Tatiana; Lomba, Enrique; Bores, Cecilia

    2012-11-13

    The stability of complexes of a recently synthetized (Scott et al. J. Am. Chem. Soc.2011, 134, 107) opened nanocontainer C50H10 with several guest molecules, H2, N2, CO, HCN, H2O, CO2, CS2, H2S, C2H2, NH3, CH4, CH3CN, CH3OH, CH3CCH, 2-butyne, methyl halides, and with noble gas atoms, has been examined by means of symmetry-adapted perturbation theory of intermolecular interactions, which fully incorporates all important energy components, including a difficult dispersion term. All complexes under scrutiny have been found stable for all studied guests at 0 K, but entropic effects cause many of them to dissociate into constituent molecules under standard conditions. The estimation of temperature at which the Gibbs free energy ΔG = 0 revealed that the recently observed (Scott et al. J. Am. Chem. Soc.2011, 134, 107) complex CS2@C50H10 is the most stable at room temperature while the corresponding complexes with HCN and Xe guests should decompose at ca. 310 K and that with CO2 at room temperature (ca. 300 K). In agreement with the ΔG estimation, molecular dynamics simulations performed in vacuum for the CS2@C50H10 complex predicted that the complex is stable but decomposes at ca. 350 K. The MD simulations in CHCl3 solution showed that the presence of solvent stabilizes the CS2@C50H10 complex in comparison to vacuum. Thus, for the complexes obtained in solution the CO2 gas responsible for the greenhouse effect could be stored in the C50H10 nanotube.

  3. Risk of simulated microgravity on testicular injury induced by high-LET carbon-ion beams in mice

    International Nuclear Information System (INIS)

    This study investigated the impact of simulated microgravity on acute injury induced by low doses of carbon ions in male reproductive organs of mice, and determined alterations in spermatogenic function and expression levels of apoptotic factors in mice following exposure to acute irradiation after 7 days of simulated microgravity. The results demonstrated that significant reductions in spermatozoa, primary spermatocytes and spermatogonia, and increased globular cells in seminiferous tubule and pro-apoptotic proteins were observed in the group exposed to over 0.4 Gy irradiation. Collectively, the data suggest that lesions inflicted by simulated microgravity are not markedly modified by lower doses of irradiation (0.2 Gy) in mouse testis compared to the control group. However, testicular impairments were markedly evident in the group exposed to higher doses of carbon ions plus simulated microgravity, which may be due at least in part to elevated apoptosis initiated by the mitochondrial apoptosis pathway in germ cells. (authors)

  4. Graphene crystal growth by thermal precipitation of focused ion beam induced deposition of carbon precursor via patterned-iron thin layers

    Directory of Open Access Journals (Sweden)

    Rius Gemma

    2014-01-01

    Full Text Available Recently, relevant advances on graphene as a building block of integrated circuits (ICs have been demonstrated. Graphene growth and device fabrication related processing has been steadily and intensively powered due to commercial interest; however, there are many challenges associated with the incorporation of graphene into commercial applications which includes challenges associated with the synthesis of this material. Specifically, the controlled deposition of single layer large single crystal graphene on arbitrary supports, is particularly challenging. Previously, we have reported the first demonstration of the transformation of focused ion beam induced deposition of carbon (FIBID-C into patterned graphitic layers by metal-assisted thermal treatment (Ni foils. In this present work, we continue exploiting the FIBID-C approach as a route for graphene deposition. Here, thin patterned Fe layers are used for the catalysis of graphenization and graphitization. We demonstrate the formation of high quality single and few layer graphene, which evidences, the possibility of using Fe as a catalyst for graphene deposition. The mechanism is understood as the minute precipitation of atomic carbon after supersaturation of some iron carbides formed under a high temperature treatment. As a consequence of the complete wetting of FIBID-C and patterned Fe layers, which enable graphene growth, the as-deposited patterns do not preserve their original shape after the thermal treatment

  5. Estudio Experimental de Piezas Lineales de Hormigón Reforzadas con Fibras de Carbono Experimental Study of Reinforced Concrete Beams Strengthened with Carbon Fibers

    Directory of Open Access Journals (Sweden)

    M. Valcuende

    2004-01-01

    Full Text Available Se ha estudiado el comportamiento de seis vigas reforzadas simultáneamente con láminas y tejidos de fibra de carbono. Se analiza, para este tipo de refuerzos, la validez de dos de los métodos de cálculo posiblemente más utilizados. En ambos métodos se plantean las ecuaciones de equilibrio de fuerzas y momentos, pero se introducen suposiciones diferentes: i el acero tiene suficiente capacidad plástica para no romperse y ii el agotamiento se produce siempre por rotura de la lámina. Los resultados obtenidos ponen de manifiesto que refuerzos de láminas y tejidos de fibra de carbono influyen notablemente sobre las piezas, mejorando su capacidad portante y modificando su comportamiento estructural en cuanto a rigidez y ductilidadA study on the behaviour of six beams reinforced with carbon fiber laminates and fabrics was done. The validity of the two most commonly used methods of evaluating the effects of these reinforcements was analyzed. Both methods propose equilibrium equations based on forces and moments, although introducing two different suppositions: i that the steel posesses enough elasticity to avoid breakage, and ii failure is always produced by the breakage of the laminate. The results obtained demonstrate that carbon fiber laminates and fabric reinforcements have notable influence on the pieces, improving their loading capacities and modifying their structural behavior regarding stiffness and ductility

  6. Increased strength characteristics of low carbon micro-alloyed steel grade 10g2fb

    OpenAIRE

    Nosenko, O. P.

    2016-01-01

    Aim. The purpose of research is the search of new technological methods of increasing mechanical and performance properties of the steel grade 10G2FB for metal structures of responsible appointment. Methods. The structure of the steel samples wasstudied by qualitative and quantitative light microscopy at microscopes "Epikvant", "Neofot-2". Testing mechanical properties of tensile was carried out according to DSTU EN 10002 1:. 2006, toughness was determined on a U- and V-notch samples for Stat...

  7. Laser beam welding quality monitoring system based in high-speed (10 kHz) uncooled MWIR imaging sensors

    Science.gov (United States)

    Linares, Rodrigo; Vergara, German; Gutiérrez, Raúl; Fernández, Carlos; Villamayor, Víctor; Gómez, Luis; González-Camino, Maria; Baldasano, Arturo; Castro, G.; Arias, R.; Lapido, Y.; Rodríguez, J.; Romero, Pablo

    2015-05-01

    The combination of flexibility, productivity, precision and zero-defect manufacturing in future laser-based equipment are a major challenge that faces this enabling technology. New sensors for online monitoring and real-time control of laserbased processes are necessary for improving products quality and increasing manufacture yields. New approaches to fully automate processes towards zero-defect manufacturing demand smarter heads where lasers, optics, actuators, sensors and electronics will be integrated in a unique compact and affordable device. Many defects arising in laser-based manufacturing processes come from instabilities in the dynamics of the laser process. Temperature and heat dynamics are key parameters to be monitored. Low cost infrared imagers with high-speed of response will constitute the next generation of sensors to be implemented in future monitoring and control systems for laser-based processes, capable to provide simultaneous information about heat dynamics and spatial distribution. This work describes the result of using an innovative low-cost high-speed infrared imager based on the first quantum infrared imager monolithically integrated with Si-CMOS ROIC of the market. The sensor is able to provide low resolution images at frame rates up to 10 KHz in uncooled operation at the same cost as traditional infrared spot detectors. In order to demonstrate the capabilities of the new sensor technology, a low-cost camera was assembled on a standard production laser welding head, allowing to register melting pool images at frame rates of 10 kHz. In addition, a specific software was developed for defect detection and classification. Multiple laser welding processes were recorded with the aim to study the performance of the system and its application to the real-time monitoring of laser welding processes. During the experiments, different types of defects were produced and monitored. The classifier was fed with the experimental images obtained. Self

  8. Monte Carlo Calculations of Dose to Medium and Dose to Water for Carbon Ion Beams in Various Media

    DEFF Research Database (Denmark)

    Herrmann, Rochus; Petersen, Jørgen B.B.; Jäkel, Oliver;

    treatment plans. Here, we quantisize the effect of dose to water vs. dose to medium for a series of typical target materials found in medical physics. 2     Material and Methods The Monte Carlo code FLUKA [Battistioni et al. 2007] is used to simulate the particle fluence spectrum in a series of target......1     Background In clinical practice the quantity dose to water (Dw ) is used as a reference standard for dosimeters and treatment planning systems. Treatment planning systems usually rely on analytical representation of the particle beam, which are normally expressed as dose with respect to water...... for water. This represents the case that our “detector” is an infinitesimal small non-perturbing entity made of water, where charged particle equilibrium can be assumed following the Bragg-Gray cavity theory. Dw and Dm are calculated for typical materials such as bone, brain, lung and soft-tissues using...

  9. Preliminary study of window silicate glass powder for EPR dosimetry with 10-MeV electron beam irradiation

    International Nuclear Information System (INIS)

    Window silicate glass powder has been evaluated as a possible high dose dosimeter using EPR (Electron Paramagnetic Resonance) technique. In this work window glass powder with maximum dimension of 700 μm was irradiated with 10 MeV electrons with doses ranging from 580 Gy to 46.52 kGy. The EPR response of the irradiated samples showed a linear behavior to applied doses up to 8 kGy. The EPR spectra of NBOHC (Non-Bonding Oxygen Hole Center) was found at g1 = 2.0092 ± 0.0001 and g2 = 2.0042 ± 0.0001. The line widths of all spectra were found to be the same. Finally, the thermal fading of EPR intensity was studied for 70 days and showed a sharp decline on the first day. This fading continued up to almost 15 days and then the slope of the decay-curve tended to gradual changes up to 50 days. Afterwards, it presented a fairly constant value with time and a predictable stability was achieved.

  10. Comparison between computed and measured response of silicon strip detectors exposed to carbon, calcium and ruthenium ion beams

    International Nuclear Information System (INIS)

    The response of silicon strip detectors exposed to energetic heavy ions in the energy interval from 0.3 up to 1.4 GeV/u has been measured at the SIS accelerator at GSI. The energy deposit spectra are characterized by their mean values and widths. The carbon data, at various energies, agree within the accuracy of the measurements with the computed response of the detector. The measured widths of the energy deposit spectra for ruthenium are narrower than those calculated by the appropriate Vavilov distributions. Energetic δ-rays overflowing from the silicon detector is considered as a possible explanation for the disagreement between computed and measured widths

  11. Comparison between computed and measured response of silicon strip detectors exposed to carbon, calcium and ruthenium ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Codino, A. E-mail: antonio.codino@codino-pc.pg.infn.it; Plouin, F.; Bellachioma, C.; Brunetti, M.T.; Checcucci, B.; Federico, C.; Lanfranchi, M.; Maffei, P.; Miozza, M.; Vocca, H

    2003-09-01

    The response of silicon strip detectors exposed to energetic heavy ions in the energy interval from 0.3 up to 1.4 GeV/u has been measured at the SIS accelerator at GSI. The energy deposit spectra are characterized by their mean values and widths. The carbon data, at various energies, agree within the accuracy of the measurements with the computed response of the detector. The measured widths of the energy deposit spectra for ruthenium are narrower than those calculated by the appropriate Vavilov distributions. Energetic {delta}-rays overflowing from the silicon detector is considered as a possible explanation for the disagreement between computed and measured widths.

  12. Studies of Energy Recovery Linacs at Jefferson Laboratory: 1 GeV Demonstration of Energy Recovery at CEBAF and Studies of the Multibunch, Multipass Beam Breakup Instability in the 10 kW FEL Upgrade Driver

    Energy Technology Data Exchange (ETDEWEB)

    Tennant, Christopher D. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2006-10-01

    An energy recovering linac (ERL) offers an attractive alternative for generating intense beams of charged particles by approaching the operational efficiency of a storage ring while maintaining the superior beam quality typical of a linear accelerator. Two primary physics challenges exist in pushing the frontier of ERL performance. The first is energy recovering a high energy beam while demonstrating operational control of two coupled beams in a common transport channel. The second is controlling the high average current effects in ERLs, specifically a type of beam instability called multipass beam breakup (BBU). This work addresses both of these issues. A successful 1 GeV energy recovery demonstration with a maximum-to-injection energy ratio of 51:1 was carried out on the Continuous Electron Beam Accelerator Facility at Jefferson Laboratory in an effort to address issues related to beam quality preservation in a large scale system. With a 1.3 km recirculation length and containing 312 superconducting radio frequency (SRF) cavities, this experiment has demonstrated energy recovery on the largest scale, and through the largest SRF environment, to date. The BBU instability imposes a potentially severe limitation to the average current that can be accelerated in an ERL. Simulation results for Jefferson Laboratory's 10 kW free electron laser (FEL) Upgrade Driver predict the occurrence of BBU below the nominal operating current. Measurements of the threshold current are described and shown to agree to within 10% of predictions from BBU simulation codes. This represents the first time the codes have been benchmarked with experimental data. With BBU limiting the beam current, several suppression schemes were developed. These include direct damping of the higher-order mode using two different cavity-based feedbacks and modifying the electron beam optics to reduce the coupling between the beam and mode. Specifically the effect of implementing (1) point

  13. Elemental and organic carbon in PM10: a one year measurement campaign within the European Monitoring and Evaluation Programme EMEP

    Directory of Open Access Journals (Sweden)

    W. Maenhaut

    2007-03-01

    Full Text Available In the present study, ambient aerosol (PM10 concentrations of elemental carbon (EC, organic carbon (OC, and total carbon (TC are reported for 12 European rural background sites and two urban background sites following a one-year (1 July 2002–1 July 2003 sampling campaign within the European Monitoring and Evaluation Programme, EMEP (http://www.emep.int/. The purpose of the campaign was to assess the feasibility of performing EC and OC monitoring on a regular basis and to obtain an overview of the spatial and seasonal variability on a regional scale in Europe. Analyses were performed using the thermal-optical transmission (TOT instrument from Sunset Lab Inc., operating according to a NIOSH derived temperature program. The annual mean mass concentration of EC ranged from 0.17±0.19 μg m−3 (mean ± SD at Birkenes (Norway to 1.83±1.32 μg m−3 at Ispra (Italy. The corresponding range for OC was 1.20±1.29 μg m−3 at Mace Head (Ireland to 7.79±6.80 μg m−3 at Ispra. On average, annual concentrations of EC, OC, and TC were three times higher for rural background sites in Central, Eastern and Southern Europe compared to those situated in the Northern and Western parts of Europe. Wintertime concentrations of EC and OC were higher than those recorded during summer for the majority of the sites. Moderate to high Pearson correlation coefficients (rp (0.50–0.94 were observed for EC versus OC for the sites investigated. The lowest correlation coefficients were noted for the three Scandinavian sites: Aspvreten (SE, Birkenes (NO, and Virolahti (FI, and the Slovakian site Stara Lesna, and are suggested to reflect biogenic sources, wild and prescribed fires. This suggestion is supported by the fact that higher concentrations of OC are observed for summer compared to winter for these sites. For the rural background sites, total carbonaceous material accounted for 30±9% of PM10, of which 27±9% could be attributed to organic matter (OM and 3.4±1.0

  14. Elemental and organic carbon in PM10: a one year measurement campaign within the European Monitoring and Evaluation Programme EMEP

    Directory of Open Access Journals (Sweden)

    W. Maenhaut

    2007-11-01

    Full Text Available In the present study, ambient aerosol (PM10 concentrations of elemental carbon (EC, organic carbon (OC, and total carbon (TC are reported for 12 European rural background sites and two urban background sites following a one-year (1 July 2002–1 July 2003 sampling campaign within the European Monitoring and Evaluation Programme, EMEP http://www.emep.int/. The purpose of the campaign was to assess the feasibility of performing EC and OC monitoring on a regular basis and to obtain an overview of the spatial and seasonal variability on a regional scale in Europe. Analyses were performed using the thermal-optical transmission (TOT instrument from Sunset Lab Inc., operating according to a NIOSH derived temperature program. The annual mean mass concentration of EC ranged from 0.17±0.19 μg m−3 (mean ± SD at Birkenes (Norway to 1.83±1.32 μg m−3 at Ispra (Italy. The corresponding range for OC was 1.20±1.29 μg m−3 at Mace Head (Ireland to 7.79±6.80 μg m−3 at Ispra. On average, annual concentrations of EC, OC, and TC were three times higher for rural background sites in Central, Eastern and Southern Europe compared to those situated in the Northern and Western parts of Europe. Wintertime concentrations of EC and OC were higher than those recorded during summer for the majority of the sites. Moderate to high Pearson correlation coefficients (rp (0.50–0.94 were observed for EC versus OC for the sites investigated. The lowest correlation coefficients were noted for the three Scandinavian sites: Aspvreten (SE, Birkenes (NO, and Virolahti (FI, and the Slovakian site Stara Lesna, and are suggested to reflect biogenic sources, wild and prescribed fires. This suggestion is supported by the fact that higher concentrations of OC are observed for summer compared to winter for these sites. For the rural background sites, total carbonaceous material accounted for 30±9% of PM10, of which 27±9% could be attributed to organic matter (OM and 3.4±1.0

  15. Experimental determination of kQ factors for cylindrical ionization chambers in 10 cm × 10 cm and 3 cm × 3 cm photon beams from 4 MV to 25 MV

    Science.gov (United States)

    Krauss, A.; Kapsch, R. P.

    2014-08-01

    For the ionometric determination of absorbed dose to water, Dw, in megavoltage photon beams from a linear accelerator, beam-quality-dependent correction factors, kQ, are used for the ionization chambers. By using a water calorimeter, these factors can be determined experimentally and with substantially lower standard uncertainties compared to calculated values of the kQ, which are published in various dosimetry protocols. In this investigation, kQ for different types of cylindrical ionization chambers (NE 2561, NE 2571, FC 65 G) were determined experimentally in 10 cm × 10 cm photon beams from 4 MV to 25 MV (corresponding beam quality index TPR20,10 from 0.64 to 0.80). The measurements were carried out at the linear accelerator facility of the Physikalisch-Technische Bundesanstalt. It is shown that the kQ factors for a single ionization chamber in 10 cm × 10 cm photon beams can be measured with a relative standard uncertainty of 0.31%. In addition to these measurements in 10 cm × 10 cm fields, kQ factors for the NE 2561 chamber were also determined in smaller 3 cm × 3 cm photon beams between 6 MV and 25 MV. In this case, relative standard uncertainties between 0.35 % and 0.38 % are achieved for the kQ factors. It is found for this ionization chamber, that the ratio of the kQ factors in 3 cm × 3 cm and in 10 cm × 10 cm beams increases with increasing TPR20,10 to reach a value of 1.0095 at TPR20,10 = 0.8 with a relative standard uncertainty of 0.4 %.

  16. A comparison study between atomic and ionic nitrogen doped carbon films prepared by ion beam assisted cathode arc deposition at various pulse frequencies

    International Nuclear Information System (INIS)

    A comparison study of microstructure and bonds composition of carbon nitride (CNx) films fabricated at atomic and ionic nitrogen source by pulse cathode arc method was presented. The relative fractions of CN/CC bonds, N-sp3C/N-sp2C and graphite-like/pyridine-like N bonding configurations in the CN films were evaluated by combining C1s and N1s X-ray photoelectron spectroscopy with the hardness and optical band gap measurement. The dependence of microstructure (quantity, size and disordering degree of Csp2 clusters) of CNx films on the nitrogen source and pulse frequency was determined by Raman spectroscopy. Films with high atomic ratio of nitrogen/carbon (0.17) and high hardness were produced at ionic nitrogen source and low pulse frequency. The results showed that ionic nitrogen source facilitated the formation of CN bonds and N-sp2C bonding configurations (mainly in graphite-like N form). Moreover presenting an optimum pulse frequency (∼10 Hz) leaded to the most nitrogen coordinated with sp3-C and the highest ratio of CN/CC bonds in the CNx films. An equilibrium action mechanism might exist between the quantity and energy of carbon and nitrogen ions/atoms, giving more nitrogen-incorporated carbon materials. These allow us to obtain the high content of N-Csp3 bonding and expected bonding structure by optimizing pulse frequency and nitrogen source.

  17. First fringes with an integrated-optics beam combiner at 10 μm. A new step towards instrument miniaturization for mid-infrared interferometry

    Science.gov (United States)

    Labadie, L.; Martín, G.; Anheier, N. C.; Arezki, B.; Qiao, H. A.; Bernacki, B.; Kern, P.

    2011-07-01

    Context. Observations of milliarcsecond-resolution scales and high dynamic range hold a central place in the exploration of distant planetary systems in order to achieve, for instance, the spectroscopic characterization of exo-Earths or the detailed mapping of their protoplanetary disc birthplace. Multi-aperture infrared interferometry, either from the ground or from space, is a very powerful technique to tackle these goals. However, significant technical efforts still need to be undertaken to achieve a simplification of these instruments if we wish to recombine the light from a large number of telescopes. Integrated-optics concepts appear to be a suitable alternative to the current conventional designs, especially if their use can be extended to a higher number of astronomical bands. Aims: This article reports, for the first time to our knowledge, the experimental demonstration of the feasibility of an integrated-optics approach to mid-infrared beam combination for single-mode stellar interferometry. Methods: We fabricated a two-telescope beam combiner prototype integrated on a substrate of chalcogenide glass, a material transparent from ~1 μm to ~14 μm. We developed laboratory tools to characterize in the mid-infrared the modal properties and the interferometric capabilities of our device. Results: We obtain interferometric fringes at 10 μm and measure a mean contrast V = 0.981 ± 0.001 with high repeatability over one week and high stability over a time-period of ~5 h. We show experimentally - as well as on the basis of modeling considerations - that the component has a single-mode behavior at this wavelength, which is essential to achieve high-accuracy interferometry. From previous studies, the propagation losses are estimated to be 0.5 dB/cm for this type of component. We also discuss possible issues that may impact the interferometric contrast. Conclusions: The IO beam combiner performs well at the tested wavelength. We also anticipate the requirement of a

  18. Low-Dose (10-Gy) Total Skin Electron Beam Therapy for Cutaneous T-Cell Lymphoma: An Open Clinical Study and Pooled Data Analysis

    International Nuclear Information System (INIS)

    Purpose: Cutaneous T-cell lymphomas (CTCLs) are dominated by mycosis fungoides (MF) and Sézary syndrome (SS), and durable disease control is a therapeutic challenge. Standard total skin electron beam therapy (TSEBT) is an effective skin-directed therapy, but the possibility of retreatments is limited to 2 to 3 courses in a lifetime due to skin toxicity. This study aimed to determine the clinical effect of low-dose TSEBT in patients with MF and SS. Methods and Materials: In an open clinical study, 21 patients with MF/SS stages IB to IV were treated with low-dose TSEBT over <2.5 weeks, receiving a total dose of 10 Gy in 10 fractions. Data from 10 of these patients were published previously but were included in the current pooled data analysis. Outcome measures were response rate, duration of response, and toxicity. Results: The overall response rate was 95% with a complete cutaneous response or a very good partial response rate (<1% skin involvement with patches or plaques) documented in 57% of the patients. Median duration of overall cutaneous response was 174 days (5.8 months; range: 60-675 days). TSEBT-related acute adverse events (grade 1 or 2) were observed in 60% of patients. Conclusions: Low-dose (10-Gy) TSEBT offers a high overall response rate and is relatively safe. With this approach, reirradiation at times of relapse or progression is likely to be less toxic than standard dose TSEBT. It remains to be established whether adjuvant and combination treatments can prolong the beneficial effects of low-dose TSEBT

  19. Low-Dose (10-Gy) Total Skin Electron Beam Therapy for Cutaneous T-Cell Lymphoma: An Open Clinical Study and Pooled Data Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kamstrup, Maria R., E-mail: mkam0004@bbh.regionh.dk [Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen (Denmark); Gniadecki, Robert [Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen (Denmark); Iversen, Lars [Department of Dermatology, Aarhus University Hospital, Aarhus (Denmark); Skov, Lone [Department of Dermatology, Gentofte Hospital, University of Copenhagen, Copenhagen (Denmark); Petersen, Peter Meidahl [Department of Oncology and Hematology, Rigshospitalet, University of Copenhagen, Copenhagen (Denmark); Loft, Annika [Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen (Denmark); Specht, Lena [Department of Oncology and Hematology, Rigshospitalet, University of Copenhagen, Copenhagen (Denmark)

    2015-05-01

    Purpose: Cutaneous T-cell lymphomas (CTCLs) are dominated by mycosis fungoides (MF) and Sézary syndrome (SS), and durable disease control is a therapeutic challenge. Standard total skin electron beam therapy (TSEBT) is an effective skin-directed therapy, but the possibility of retreatments is limited to 2 to 3 courses in a lifetime due to skin toxicity. This study aimed to determine the clinical effect of low-dose TSEBT in patients with MF and SS. Methods and Materials: In an open clinical study, 21 patients with MF/SS stages IB to IV were treated with low-dose TSEBT over <2.5 weeks, receiving a total dose of 10 Gy in 10 fractions. Data from 10 of these patients were published previously but were included in the current pooled data analysis. Outcome measures were response rate, duration of response, and toxicity. Results: The overall response rate was 95% with a complete cutaneous response or a very good partial response rate (<1% skin involvement with patches or plaques) documented in 57% of the patients. Median duration of overall cutaneous response was 174 days (5.8 months; range: 60-675 days). TSEBT-related acute adverse events (grade 1 or 2) were observed in 60% of patients. Conclusions: Low-dose (10-Gy) TSEBT offers a high overall response rate and is relatively safe. With this approach, reirradiation at times of relapse or progression is likely to be less toxic than standard dose TSEBT. It remains to be established whether adjuvant and combination treatments can prolong the beneficial effects of low-dose TSEBT.

  20. The relative biological effectiveness for carbon and oxygen ion beams using the raster-scanning technique in hepatocellular carcinoma cell lines.

    Directory of Open Access Journals (Sweden)

    Daniel Habermehl

    Full Text Available BACKGROUND: Aim of this study was to evaluate the relative biological effectiveness (RBE of carbon (12C and oxygen ion (16O-irradiation applied in the raster-scanning technique at the Heidelberg Ion beam Therapy center (HIT based on clonogenic survival in hepatocellular carcinoma cell lines compared to photon irradiation. METHODS: Four human HCC lines Hep3B, PLC, HepG2 and HUH7 were irradiated with photons, 12C and 16O using a customized experimental setting at HIT for in-vitro trials. Cells were irradiated with increasing physical photon single doses of 0, 2, 4 and 6 Gy and heavy ion-single doses of 0, 0.125, 0.5, 1, 2, 3 Gy (12C and 16O. SOBP-penetration depth and extension was 35 mm +/-4 mm and 36 mm +/-5 mm for carbon ions and oxygen ions respectively. Mean energy level and mean linear energy transfer (LET were 130 MeV/u and 112 keV/um for 12C, and 154 MeV/u and 146 keV/um for 16O. Clonogenic survival was computated and relative biological effectiveness (RBE values were defined. RESULTS: For all cell lines and both particle modalities α- and β-values were determined. As expected, α-values were significantly higher for 12C and 16O than for photons, reflecting a steeper decline of the initial slope of the survival curves for high-LET beams. RBE-values were in the range of 2.1-3.3 and 1.9-3.1 for 12C and 16O, respectively. CONCLUSION: Both irradiation with 12C and 16O using the raster-scanning technique leads to an enhanced RBE in HCC cell lines. No relevant differences between achieved RBE-values for 12C and 16O were found. Results of this work will further influence biological-adapted treatment planning for HCC patients that will undergo particle therapy with 12C or 16O.

  1. Properties of carbon-based structures synthesized in nuclear reactions induced by bremsstrahlung γ quanta with threshold energy of 10 MeV at helium pressure of 1.1 kbar

    Science.gov (United States)

    Didyk, A. Yu.; Wiśniewski, R.

    2016-07-01

    Helium gas with an initial pressure of about 1.1 kbar inside a high-pressure chamber (HeHPC) has been irradiated by bremsstrahlung γ quanta with a threshold energy of 10 MeV for 1.0 × 105 s produced by an electron-beam current of 22-24 μA. After opening the HeHPC, the residual pressure of helium is equal to 430 bar. Synthesized black foils with a variety of other objects are found inside the HeHPC. They are located on the inner surfaces of the reaction chamber made of high-purity copper (99.99%), the entrance the window of γ quanta made of beryllium bronze and a copper container of nuclear and chemical reaction products. Elemental analysis with the use of scanning electron microscopy and X-ray microprobe analysis has revealed that the foils contain predominantly carbon and small quantities of other elements from carbon to iron. The results are in good agreement with the cycle of investigations of the authors devoted to the γ-quanta irradiation of dense hydrogen and helium gases in the presence (absence) of metals in a reaction chamber.

  2. Experiments investigating the generation and transport of 10--12 MeV, 30-kA, mm-size electron beams with linear inductive voltage adders

    Energy Technology Data Exchange (ETDEWEB)

    Mazarakis, M.G.; Poukey, J.W.; Maenchen, J.E.

    1997-06-01

    The authors present the design, analysis, and results of the high-brightness electron beam experiments currently under investigation at Sandia National Laboratories. The anticipated beam parameters are the following: 8--12 MeV, 35--50 kA, 30--60 ns FWHM, and 0.5-mm rms beam radius. The accelerators utilized are SABRE and HERMES III. Both are linear inductive voltage adders modified to higher impedance and fitted with magnetically immersed foil less electron diodes. In the strong 20--50 Tesla solenoidal magnetic field of the diode, mm-size electron beams are generated and propagated to a beam stop. The electron beam is field emitted from mm-diameter needle-shaped cathode electrode and is contained in a similar size envelop by the strong magnetic field. These extremely space charge dominated beams provide the opportunity to study beam dynamics and possible instabilities in a unique parameter space. The SABRE experiments are already completed and have produced 30-kA, 1.5-mm FWHM electron beams, while the HERMES-III experiments are on-going.

  3. Production of an accelerated oxygen-14 beam

    CERN Document Server

    Powell, J; Cerny, J

    2003-01-01

    BEARS is an ongoing project to provide a light-ion radioactive-beam capability at the 88-Inch Cyclotron at LBNL. Light radioactive isotopes are produced at a 10 MeV proton medical cyclotron, transported 350 m via a high-speed gas transport capillary, cryogenically separated, and injected into the 88-Inch Cyclotron's ion source. The first radioactive beam successfully accelerated was carbon-11 and beams of intensity more than 10 sup 8 ions/s have been utilized for experiments. Development of oxygen-14 as the second BEARS beam presented considerable technical challenges, both due to its short half-life of 71 s and the radiation chemistry of oxygen in the target. The usual techniques developed for medical uses of oxygen-15 involve the addition of significant amounts of carrier oxygen, something that would overload the ion source. As a solution, oxygen-14 is produced as water in a carrier-free form, and is chemically converted in two steps to carbon dioxide, a form readily usable by the BEARS. This system has bee...

  4. Simulations of Full Impact of the LHC Beam With a Solid Graphite Target

    CERN Document Server

    Tahir, N A; Brugger, M; Shutov, A; Lomonosov, I V; Piriz, A R; Hoffmann, D H H

    2009-01-01

    The Large Hadron Collider (LHC) will operate with 7~TeV/c protons with a luminosity of 10$^{34}$ cm$^{-2}$s$^{-1}$. This requires two beams, each with 2808 bunches. The nominal intensity per bunch is 1.15$\\;\\times\\;$10$^{11}$ protons and the total energy stored in each beam is 362 MJ. In previous papers, the mechanisms causing equipment damage in case of a failure of the machine protection system was discussed, assuming that the entire beam is deflected onto a copper target. Another failure scenario is the deflection of beam, or part of it, into carbon material. Carbon collimators and beam absorbers are installed in many locations around the LHC close to the beam, since carbon is the material that is most suitable to absorb the beam energy without being damaged. In case of a failure, it is very likely that such absorbers are hit first, for example, when the beam is accidentally deflected. Some type of failures need to be anticipated, such as accidental firing of injection and extraction kicker magnets leading...

  5. Relationship between plant growth and cytological effect in root apical meristem after exposure of wheat dry seeds to carbon ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Qingfang [Radiobiology Laboratory, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, Gansu Province 730000 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Wang, Zhuanzi; Zhou, Libin; Qu, Ying; Lu, Dong [Radiobiology Laboratory, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, Gansu Province 730000 (China); Yu, Lixia; Du, Yan [Radiobiology Laboratory, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, Gansu Province 730000 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Jin, Wenjie [Radiobiology Laboratory, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, Gansu Province 730000 (China); Li, Wenjian, E-mail: wjli@impcas.ac.cn [Radiobiology Laboratory, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, Gansu Province 730000 (China)

    2013-06-15

    In order to analyze the relationship between plant growth and cytological effects, wheat dry seeds were exposed to various doses of {sup 12}C{sup 6+} beams and the biological endpoints reflecting plant growth and root apical meristem (RAM) activities were investigated. The results showed that most of the seeds were able to germinate normally within all dose range, while the plant survival rate descended at higher doses. The seedling growth including root length and seedling height also decreased significantly at higher doses. Mitotic index (MI) in RAM had no changes at 10 and 20 Gy and decreased obviously at higher doses and the proportion of prophase cells had the same trend with MI. These data suggested that RAM cells experienced cell cycle arrest, which should be responsible for the inhibition of root growth after exposure to higher doses irradiation. Moreover, various types of chromosome aberrations (CAs) were observed in the mitotic cells. The frequencies of mitotic cells with lagging chromosomes and these with anaphase bridges peaked around 60 Gy, while the frequencies of these with fragments increased as the irradiation doses increased up to 200 Gy. The total frequencies of mitotic cells with CAs induced by irradiation increased significantly with the increasing doses. The serious damage of mitotic chromosomes maybe caused cell cycle arrest or cell death. These findings suggested that the influences of {sup 12}C{sup 6+} beams irradiation on plant growth were related to the alternation of mitotic activities and the chromosomal damages in RAM.

  6. An overview of nuclear micro-beam analysis of surface and bulk fuel retention in carbon-fibre composites from Tore Supra

    International Nuclear Information System (INIS)

    Surface and bulk retention of deuterium in tiles of the pump limiter from Tore Supra was examined with nuclear reaction analysis using both standard and micro-beam techniques. The aim was to determine the variations in the content and distribution of fuel species in carbon-fibre composites. On plasma-facing surfaces from the deposition zone, the D content reaches 2.5 x 1019 cm-2 in about 8 μm thick top layer, but lateral differences reach even more than one order of magnitude. This is also measured in the erosion zone: 6.6 x 1017 cm-2 to 7.7 x 1018 cm-2 D atoms. Bulk content was examined on cross-sections opened by fracturing the tiles. Fuel is detected up to the depth of 1-1.5 mm beneath the plasma-facing surface in tiles from both the erosion and deposition zones. It occurs in bands, about 100 μm wide and several mm long, roughly parallel to the original plasma-facing surface.

  7. Rabi Wave Packets and Peculiarities of Raman Scattering in Carbon Nanotubes, Produced by High Energy Ion Beam Modification of Diamond Single Crystals

    CERN Document Server

    Yearchuck, Dmitry

    2011-01-01

    QED-model for multichain coupled qubit system, proposed in \\cite{Part1}, was confirmed by Raman scattering studies of quasi-1D carbon zigzag-shaped nanotubes (CZSNTs), produced by high energy ion beam modification of natural diamond single crystals. Multichain coupled qubit system represents itself Su-Schriffer-Heeger $\\sigma$-polaron lattice, formed in CZSNTs plus quantized external electromagnetic (EM) field. New quantum optics phenomenon - Rabi waves, predicted in \\cite{Slepyan_Yerchak} has experimentally been identified for the first time. It is shown, that Raman spectra in quasi-1D CZSNTs are quite different in comparison with well known Raman spectra in 2D those ones. They characterized by semiclassical consideration by the only one vibronic mode of Su-Schriffer-Heeger $\\sigma$-polaron lattice instead of longitudinal and transverse optical phonon $G^+$ and $G^-$modes and the out-of-plane radial breathing mode, which are observed in Raman spectra of 2D single wall nanotubes. It is consequence of 2D - 1D ...

  8. Simple model of bulk and surface excitation effects to inelastic scattering in low-energy electron beam irradiation of multi-walled carbon nanotubes

    Energy Technology Data Exchange (ETDEWEB)

    Kyriakou, Ioanna; Emfietzoglou, Dimitris [Medical Physics Lab, University of Ioannina Medical School, 451 10 Ioannina (Greece); Garcia-Molina, Rafael [Departamento de Fisica - CIOyN, Universidad de Murcia, E-30100 Murcia (Spain); Abril, Isabel [Departament de Fisica Aplicada, Universitat d' Alacant, Apartat 99, E-03080 Alacant (Spain); Kostarelos, Kostas [Nanomedicine Lab, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX (United Kingdom)

    2011-09-01

    The effect of bulk and surface excitations to inelastic scattering in low-energy electron beam irradiation of multi-walled carbon nanotubes (MWNTs) is studied using the dielectric formalism. Calculations are based on a semiempirical dielectric response function for MWCNTs determined by means of a many-pole plasmon model with parameters adjusted to available experimental spectroscopic data under theoretical sum-rule constrains. Finite-size effects are considered in the context of electron gas theory via a boundary correction term in the plasmon dispersion relations, thus, allowing a more realistic extrapolation of the electronic excitation spectrum over the whole energy-momentum plane. Energy-loss differential and total inelastic scattering cross sections as a function of electron energy and distance from the surface, valid over the energy range {approx}50-30,000 eV, are calculated with the individual contribution of bulk and surface excitations separated and analyzed for the case of normally incident and escaping electrons. The sensitivity of the results to the various approximations for the spatial dispersion of the electronic excitations is quantified. Surface excitations are shown to have a strong influence upon the shape and intensity of the energy-loss differential cross section in the near surface region whereas the general notion of a spatially invariant inelastic mean free path inside the material is found to be of good approximation.

  9. Near edge X-ray absorption fine structure study for optimization of hard diamond-like carbon film formation with Ar cluster ion beam

    CERN Document Server

    Kitagawa, T; Kanda, K; Shimizugawa, Y; Toyoda, N; Matsui, S; Yamada, I; Tsubakino, H; Matsuo, J

    2003-01-01

    Diamond-like carbon (DLC) film deposited using C sub 6 sub 0 vapor with simultaneous irradiation of an Ar cluster ion beam was characterized by a near edge X-ray absorption fine structure (NEXAFS), in order to optimize the hard DLC film deposition conditions. Contents of sp sup 2 orbitals in the films, which were estimated from NEXAFS spectra, are 30% lower than that of a conventional DLC film deposited by a RF plasma method. Those contents were obtained under the flux ratio of the C sub 6 sub 0 molecules to the Ar cluster ions to range from 1 to 20, at 5keV of Ar cluster ion acceleration energy. Average hardness of the films was 50 GPa under these flux ratios. This hardness was three times higher than that of a conventional DLC film. Furthermore, the lowest sp sup 2 content and above-mentioned high hardness were obtained at room temperature of the substrate when the depositions were performed in the range of the substrate temperature from room temperature to 250degC. (author)

  10. Simultaneous apatial and frequency domain filtering at the antenna inputs achieving up to +10dBm out-of-band/beam P 1dB

    NARCIS (Netherlands)

    Ghaffari, A.; Klumperink, E.A.M.; Vliet, van F.E.; Nauta, B.

    2013-01-01

    Multi-antenna transceivers with beam-forming are recently gaining interest for low GHz frequencies (<6GHz) [1-4]. In the antenna beam, (phase-shifted) signals from multiple antennas add constructively, improving SNR, while out-ofbeam signals add destructively (i.e. spatial filtering). Usually the su

  11. Three ways to solve the orbit of KIC11558725: a 10 day beaming sdB+WD binary with a pulsating subdwarf

    CERN Document Server

    Telting, J H; Baran, A S; Bloemen, S; Reed, M D; Oreiro, R; Farris, L; Ottosen, T A; Aerts, C; Kawaler, S D; Heber, U; Prins, S; Green, E M; Kalomeni, B; O'Toole, S J; Mullally, F; Sanderfer, D T; Smith, J C; Kjeldsen, H

    2012-01-01

    The recently discovered subdwarf B (sdB) pulsator KIC11558725 features a rich g-mode frequency spectrum, with a few low-amplitude p-modes at short periods, and is a promising target for a seismic study aiming to constrain the internal structure of this star, and of sdB stars in general. We have obtained ground-based spectroscopic Balmer-line radial-velocity measurements of KIC11558725, spanning the 2010 and 2011 observing seasons. From these data we have discovered that KIC11558725 is a binary with period P=10.05 d, and that the radial-velocity amplitude of the sdB star is 58 km/s. Consequently the companion of the sdB star has a minimum mass of 0.63 M\\odot, and is therefore most likely an unseen white dwarf. We analyse the near-continuous 2010-2011 Kepler light curve to reveal orbital Doppler-beaming light variations at the 238 ppm level, which is consistent with the observed spectroscopic orbital radial-velocity amplitude of the subdwarf. We use the strongest 70 pulsation frequencies in the Kepler light cur...

  12. Speed and accuracy of a beam tracking system for treatment of moving targets with scanned ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Saito, Nami; Bert, Christoph; Chaudhri, Naved; Gemmel, Alexander; Schardt, Dieter; Durante, Marco; Rietzel, Eike [GSI Helmholtz Centre for Heavy Ion Research GmbH, Planckstrasse 1, 64291 Darmstadt (Germany)], E-mail: n.saito@gsi.de

    2009-08-21

    The technical performance of an integrated three-dimensional carbon ion pencil beam tracking system that was developed at GSI was investigated in phantom studies. Aim of the beam tracking system is to accurately treat tumours that are subject to respiratory motion with scanned ion beams. The current system provides real-time control of ion pencil beams to track a moving target laterally using the scanning magnets and longitudinally with a dedicated range shifter. The system response time was deduced to be approximately 1 ms for lateral beam tracking. The range shifter response time has been measured for various range shift amounts. A value of 16 {+-} 2 ms was achieved for a water equivalent shift of 5 mm. An additional communication delay of 11 {+-} 2 ms was taken into account in the beam tracking process via motion prediction. Accuracy of the lateral beam tracking was measured with a multi-wire position detector to {<=}0.16 mm standard deviation. Longitudinal beam tracking accuracy was parameterized based on measured responses of the range shifter and required time durations to maintain a specific particle range. For example, 5 mm water equivalence (WE) longitudinal beam tracking results in accuracy of 1.08 and 0.48 mm WE in root mean square for time windows of 10 and 50 ms, respectively.

  13. Cross-sections of large-angle hadron production in proton- and pion-nucleus interactions VI: carbon nuclei and beam momenta from ±3 GeV/c to ±15 GeV/c

    CERN Document Server

    Bolshakova, A; Chelkov, G; Dedovitch, D; Elagin, A; Emelyanov, D; Gostkin, M; Guskov, A; Kroumchtein, Z; Nefedov, Yu; Nikolaev, K; Zhemchugov, A; Dydak, F; Wotschack, J; De Min, A; Ammosov, V; Gapienko, V; Koreshev, V; Semak, A; Sviridov, Yu; Usenko, E; Zaets, V

    2010-01-01

    We report on double-differential inclusive cross-sections of the production of secondary protons, charged pions, and deuterons, in the interactions with a 5% nuclear interaction length thick stationary carbon target, of proton and pion beams with momentum from ±3 GeV/c to ±15 GeV/c. Results are given for secondary particles with production angles between 20 and 125 degrees. Cross-sections on carbon nuclei are compared with cross-sections on beryllium, copper, tantalum and lead nuclei.

  14. Carbon supported nanoparticles Pt Ru (Pt Ru/C electrocatalysts) prepared using electron beam irradiation; Preparacao de nanoparticulas de PtRu suportadas em carbono (eletrocatalisadores PtRu/C) utilizando feixe de eletrons

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Dionisio F. da; Oliveira Neto, Almir; Pino, Eddy S.; Linardi, Marcelo; Spinace, Estevam V. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Programa de Celulas a Combustivel], e-mail: espinace@ipen.br, e-mail: dfsilva@ipen.br

    2006-07-01

    Carbon-supported Pt Ru (electrocatalysts PtRu/C nanoparticles) were prepared submitting a water/ethylene glycol mixture containing Pt(IV) and Ru(III) ions and the carbon support to electron beam irradiation. The PtRu/C electrocatalysts were characterized by EDX, XRD and cyclic voltammetry and tested for methanol electro-oxidation aiming fuel cell application. The obtained PtRu/C electrocatalysts were more active for methanol electro-oxidation than the commercial PtRu/C ETEK electrocatalyst at ambient temperature. (author)

  15. Experimental Research on Reinforcing Damaged Reinforced Concrete Beams with Carbon Fiber Reinforced Plastics%碳纤维加固二次受力梁斜截面抗剪的试验研究

    Institute of Scientific and Technical Information of China (English)

    张国栋; 朱暾; 丁红瑞

    2001-01-01

    通过4根损伤的钢筋混凝土矩形简支梁的抗剪试验,对用CFRP(CarbonFiberReinforcedPlastics)补强二次受力钢筋混凝土梁斜截面强度的力学性能进行了试验研究.研究表明,用CFRP补强钢筋混凝土梁斜截面强度效果良好.%Through shear tests of four damaged rectangular cross-sectionbeams with simple supports,the strength of the inclined section of the beams reinforced with carbon fiber reinforced plastics(CFRP)is studied experimentally.The experimental results show that the effect of CFRP on beams' strengths is farourable.

  16. 碳纤维布加固锈蚀钢筋混凝土梁的疲劳性能试验%FATIGUE PERFORMANCE OF CORRODED RC BEAMS STRENGTHENED WITH CARBON FIBER COMPOSITE SHEETS

    Institute of Scientific and Technical Information of China (English)

    宋力; 张伟平

    2009-01-01

    完成了粘贴碳纤维布加固锈蚀钢筋混凝土梁的疲劳试验.试验结果表明,碳纤维布加固可以明显提高梁的疲劳寿命,减小梁的变形,提高梁的疲劳抗裂性能.因此,粘贴碳纤维布可以较大提高锈蚀钢筋混凝土梁的疲劳性能,延长锈蚀钢筋混凝土结构的使用寿命,为碳纤维布加固锈蚀钢筋混凝土结构的长期疲劳性能研究提供了试验依据.%Tests,including two corroded reinforced concrete(RC)beams strengthened with carbon fiber composite sheets and one corroded RC beams,were carried out under fatigue loadings.It is found that the fa-tigue life of beams strengthened with csrbon fiber composite sheets is greatly improved,and fatigue delforma-tion is decreased,and performance of anti-crack is obviously improved.Thus,after stuengthening with exter-ally bonded carbon fiber composite sheets,the flexural fatigue behavior of a corroded RC beam may be con-siderably improveded,the fatigue life of corrosion RC structures may be obviously increased.It sets up the test-base for the study of long-term performance of corroded RC beam reinforced with carbon fiber composite she-ets.

  17. USGS Arctic Ocean carbon cruise 2010: field activity H-03-10-AR to collect carbon data in the Arctic Ocean, August - September 2010

    Science.gov (United States)

    Robbins, Lisa L.; Yates, Kimberly K.; Gove, Matthew D.; Knorr, Paul O.; Wynn, Jonathan; Byrne, Robert H.; Liu, Xuewu

    2013-01-01

    Carbon dioxide (CO2) in the atmosphere is absorbed at the surface of the ocean by reacting with seawater to form carbonic acid, a weak, naturally occurring acid. As atmospheric carbon dioxide increases, the concentration of carbonic acid in seawater also increases, causing a decrease in ocean pH and carbonate mineral saturation states, a process known as ocean acidification. The oceans have absorbed approximately 525 billion tons of carbon dioxide from the atmosphere, or about one-quarter to one-third of the anthropogenic carbon emissions released since the beginning of the Industrial Revolution (Sabine and others, 2004). Global surveys of ocean chemistry have revealed that seawater pH has decreased by about 0.1 units (from a pH of 8.2 to 8.1) since the 1700s due to absorption of carbon dioxide (Caldeira and Wickett, 2003; Orr and others, 2005; Raven and others, 2005). Modeling studies, based on Intergovernmental Panel on Climate Change (IPCC) CO2 emission scenarios, predict that atmospheric carbon dioxide levels could reach more than 500 parts per million (ppm) by the middle of this century and 800 ppm by the year 2100, causing an additional decrease in surface water pH of 0.3 pH units. Ocean acidification is a global threat and is already having profound and deleterious effects on the geology, biology, chemistry, and socioeconomic resources of coastal and marine habitats (Raven and others, 2005; Ruttiman, 2006). The polar and sub-polar seas have been identified as the bellwethers for global ocean acidification.

  18. RBE and OER values from 10-day growth inhibition of Vicia faba roots exposed to high-energy neutron and pion beams

    International Nuclear Information System (INIS)

    Radiobiological studies using beams of 172 MeV/c negative and positive pions and 600 MeV neutrons are reported, using growth inhibition of Vicia faba primary roots as the test system. Particular emphasis is put on an investigation of the variation of the RBE and OER values along the beams absorbed in water. The effects of position in the beam, of the dose rate, and of the nuclear-interaction dose component are considered, and comparisons made using 60Co gamma-rays as the reference radiation. The observed biological effects are discussed in the light of their possible radiobiological and radiotherapeutic applications. (Auth.)

  19. Formulation of an organic carbon trajectory over a 10-year period on a restored spoil island in south-central Florida

    Science.gov (United States)

    Schafer, T.; Ellis, R.; Osborne, T.; Hicks Pries, C.

    2015-12-01

    Long-term monitoring of restoration projects aims to determine long-term sustainability and stability of restored systems. In coastal wetlands, one indicator of restoration of ecosystem function can be seen with organic matter (specifically carbon) accretion. SL-15, a spoil island in Fort Pierce, Fl was restored in 2005, and has been monitored for return to natural condition over the last 10 years.. To assess sediment carbon accretion, sediment cores were collected in a set of eight plots, located on the SL-15 mangrove island and the surrounding seagrass recruitment area. These were analyzed for organic carbon, microbial biomass carbon, extractable carbon, and total nitrogen. The biogeochemical data collected in the previous year was compared to data collected in 2005-2007. Vegetation surveys were also completed to show the build-up of organic material in accordance with vegetation shift over the 9-year period. From this information, a trajectory has been formulated on organic carbon accretion and vegetation shift from the time of orginal restoration activities. By comparison to control sites nearby, realistic estimates of time required to reach natural levels of carbon and vegetation community structure can be calculated..

  20. Crossed-beam reaction of carbon atoms with hydrocarbon molecules. V. Chemical dynamics of n-C4H3 formation from reaction of C(3Pj) with allene, H2CCCH2(X 1A1)

    Science.gov (United States)

    Kaiser, R. I.; Mebel, A. M.; Chang, A. H. H.; Lin, S. H.; Lee, Y. T.

    1999-06-01

    The crossed molecular beams technique was employed to investigate the reaction between ground state carbon atoms, C(3Pj), and allene, H2CCCH2(X 1A1), at two averaged collision energies of 19.6 and 38.8 kJ mol-1. Product angular distributions and time-of-flight spectra of C4H3 were recorded. Forward-convolution fitting of the data yields weakly polarized center-of-mass angular flux distributions isotropic at lower, but forward scattered with respect to the carbon beam at a higher collision energy. The maximum translational energy release and the angular distributions combined with ab initio and RRKM calculations are consistent with the formation of the n-C4H3 radical in its electronic ground state. The channel to the i-C4H3 isomer contributes less than 1.5%. Reaction dynamics inferred from the experimental data indicate that the carbon atom attacks the π-orbitals of the allenic carbon-carbon double bond barrierless via a loose, reactant-like transition state located at the centrifugal barrier. The initially formed cyclopropylidene derivative rotates in a plane almost perpendicular to the total angular momentum vector around its C-axis and undergoes ring opening to triplet butatriene. At higher collision energy, the butatriene complex decomposes within 0.6 ps via hydrogen emission to form the n-C4H3 isomer and atomic hydrogen through an exit transition state located 9.2 kJ mol-1 above the products. The explicit identification of the n-C4H3 radical under single collision represents a further example of a carbon-hydrogen exchange in reactions of ground state carbon atoms with unsaturated hydrocarbons. This channel opens a barrierless route to synthesize extremely reactive hydrocarbon radicals in combustion processes, interstellar chemistry, and hydrocarbon-rich atmospheres of Jupiter, Saturn, Titan, as well as Triton.

  1. Isothermal Reduction of Oxide Scale on Hot-Rolled, Low-Carbon Steel in 10 pct H2-Ar

    Science.gov (United States)

    He, Yongquan; Jia, Tao; Li, Zhifeng; Cao, Guangming; Liu, Zhenyu; Li, Jun

    2016-08-01

    The isothermal reduction of oxide scale on hot-rolled, low-carbon steel strip in 10 pct H2-Ar mixtures in the temperature range of 673 K to 1073 K (400 °C to 800 °C) was investigated by using a thermo-gravimetric analyzer (TGA). During heating under an argon atmosphere, magnetite/iron eutectoid and proeutectoid magnetite in the oxide scale successively transformed into wüstite at a temperature above 843 K (570 °C). The kinetic plot of the isothermal reduction assumes a sigmoid shape, including induction, acceleration, and finally the decaying stage. Fitting the kinetic curve to mathematical models, the reaction at 1073 K (800 °C) and 773 K (500 °C) were determined to be controlled by phase-boundary-controlled reaction and three-dimensional growth of nuclei, respectively. The reduction product varies with temperature and itself affects the kinetics. Porous and dense iron were, respectively, obtained below and above 873 K (600 °C). A "rate-minimum" was observed at 973 K (700 °C) due to the formation of dense iron that blocks the gas diffusion. Due to the structural transformation of oxide scale during heating, the reactant depends on the heating process. However, compared with the oxide scale structure, the temperature is more important in determining the reduction kinetics at temperatures above 973 K (700 °C).

  2. Isothermal Reduction of Oxide Scale on Hot-Rolled, Low-Carbon Steel in 10 pct H2-Ar

    Science.gov (United States)

    He, Yongquan; Jia, Tao; Li, Zhifeng; Cao, Guangming; Liu, Zhenyu; Li, Jun

    2016-10-01

    The isothermal reduction of oxide scale on hot-rolled, low-carbon steel strip in 10 pct H2-Ar mixtures in the temperature range of 673 K to 1073 K (400 °C to 800 °C) was investigated by using a thermo-gravimetric analyzer (TGA). During heating under an argon atmosphere, magnetite/iron eutectoid and proeutectoid magnetite in the oxide scale successively transformed into wüstite at a temperature above 843 K (570 °C). The kinetic plot of the isothermal reduction assumes a sigmoid shape, including induction, acceleration, and finally the decaying stage. Fitting the kinetic curve to mathematical models, the reaction at 1073 K (800 °C) and 773 K (500 °C) were determined to be controlled by phase-boundary-controlled reaction and three-dimensional growth of nuclei, respectively. The reduction product varies with temperature and itself affects the kinetics. Porous and dense iron were, respectively, obtained below and above 873 K (600 °C). A "rate-minimum" was observed at 973 K (700 °C) due to the formation of dense iron that blocks the gas diffusion. Due to the structural transformation of oxide scale during heating, the reactant depends on the heating process. However, compared with the oxide scale structure, the temperature is more important in determining the reduction kinetics at temperatures above 973 K (700 °C).

  3. Oxidative Carbonylation of Methanol to Dimethyl Carbonate Over Cu(II)-1,10-Phenanthroline Bromide Complexes☆

    Institute of Scientific and Technical Information of China (English)

    Zhiping Du⁎; Lihua Xiong; Zhikun Lin; Xuli Li; Yigang Ding; Yuanxin Wu

    2014-01-01

    In order to develop the catalysts with low corrosiveness for the oxidative carbonylation of methanol to dimethyl carbonate (DMC), CuBr2 was selected as the metal source to prepare Cu coordination compounds, Cu(phen)Br2, [Cu(phen)2Br]Br and [Cu(phen)3]Br2 (phen=1,10-phenanthroline). These complexes were characterized by thermogravimetric analysis and temperature-programmed reduction. Their catalytic performances were investigated. It was found that the metal coordination environments and thermal stability of the complexes played an important role in their catalytic activities. Cu(phen)Br2 exhibited the highest activity due to the lowest steric hindrance, the most positions occupied by the bromide ions and the highest thermal stability. The turnover number was up to 47.6 DMC mol·(Cu mol)−1 with selectivity of 92.8%under conditions of 120 °C, ratio of partial pressure of CO to O2 of 19:1 (below the explosion limit of CO) and catalyst concentration of 0.011 mol·L−1. Furthermore, a plausible reaction mechanism was suggested on the basis of the experimental data.

  4. Study of the electron beam weldability of 15 CD 9-10 and 18 MND 5 steels in 180 mm thickness

    International Nuclear Information System (INIS)

    Application of electron beam process is particularly attractive for butt welding of high thicknesses components. As part of the welding nuclear industry research programme, an electron beam weldability study has been carried out both on 24Cr-1Mo (A387 gr 22 cl 2) and A508 steels in 180 mm thickness. Tests which have been performed on the CEA/CEREM electron beam facilities showed good compactness of the joint as well as satisfactory metallurgical properties. The mechanical properties fulfill standard RCC-M requirements for 24Cr-1Mo, as for A508 steel though its lower harden ability. Those results show the good high thickness electron beam weldability for both steels. (authors)

  5. Measurements of hydrogen, oxygen and carbon isotope ratios by SIRA 10 mass spectrometer and some problems of their quality assurance

    International Nuclear Information System (INIS)

    Full text: Hydrogen and oxygen are two chemical elements that combined between them forms the water molecules. Hydrogen has two stable isotopes 1H and 2H, with abundance, respectively, 99.985 % and 0.015 %, while the oxygen has three stable isotopes 16O, 17O, 18O with the abundance, respectively, 99.756 %, 0.039 %, 0.205 %. Hydrogen and oxygen stable isotopes, in our laboratory, are used in the hydrology and hydrogeology studies. The 'δ' values of hydrogen and oxygen of water samples are expressed in per mille with respect to SMOW, while, for carbon is expressed in per mille with respect to PDB. The isotopic compositions of these elements are measured using the SIRA 10 mass spectrometer, which is similar with the Nier mass spectrometer. SIRA 10 mass spectrometer, destined for the measurements of the isotopic ratios of the light elements, is equipped with double inlet system and with three collectors system (for the oxygen, carbon, nitrogen etc. isotopes) and double collector system for the hydrogen isotopes. The vacuum 10-9 torr is realized by the two oil diffusion pumps. The gas samples (H2, CO2, etc.) are admitted to the ion source of the mass spectrometer, where are transformed into positive ions by the electron impact. The magnetic field is normal to the path of the ions and is realized by a permanent magnet. The quality assurance of the 'δ' determination dependent from the preparation of the gas samples and from the measurements of the isotopic ratios. Stable isotopes hydrogen of the water samples are measured through the hydrogen gas which is gained from the water by the reduction reaction with metallic Zinc in a separate line, in vacuum conditions and high temperature. The reduction process of the water was occurred not normally because in the inside of the glass balloons seems water droplets. The different experiments of the changes the water quantity, Zinc quantity, dimensions of the metallic Zinc and the temperature of the reduction reaction didn

  6. Bessel Beams

    OpenAIRE

    McDonald, Kirk T

    2000-01-01

    Scalar Bessel beams are derived both via the wave equation and via diffraction theory. While such beams have a group velocity that exceeds the speed of light, this is a manifestation of the "scissors paradox" of special relativty. The signal velocity of a modulated Bessel beam is less than the speed of light. Forms of Bessel beams that satisfy Maxwell's equations are also given.

  7. Carbon ion beam triggers both caspase-dependent and caspase-independent pathway of apoptosis in HeLa and status of PARP-1 controls intensity of apoptosis.

    Science.gov (United States)

    Ghorai, Atanu; Sarma, Asitikantha; Bhattacharyya, Nitai P; Ghosh, Utpal

    2015-04-01

    High linear energy transfer (LET) carbon ion beam (CIB) is becoming very promising tool for various cancer treatments and is more efficient than conventional low LET gamma or X-rays to kill malignant or radio-resistant cells, although detailed mechanism of cell death is still unknown. Poly (ADP-ribose) polymerase-1 (PARP-1) is a key player in DNA repair and its inhibitors are well-known as radio-sensitizer for low LET radiation. The objective of our study was to find mechanism(s) of induction of apoptosis by CIB and role of PARP-1 in CIB-induced apoptosis. We observed overall higher apoptosis in PARP-1 knocked down HeLa cells (HsiI) compared with negative control H-vector cells after irradiation with CIB (0-4 Gy). CIB activated both intrinsic and extrinsic pathways of apoptosis via caspase-9 and caspase-8 activation respectively, followed by caspase-3 activation, apoptotic body, nucleosomal ladder formation and sub-G1 accumulation. Apoptosis inducing factor translocation into nucleus in H-vector but not in HsiI cells after CIB irradiation contributed caspase-independent apoptosis. Higher p53 expression was observed in HsiI cells compared with H-vector after exposure with CIB. Notably, we observed about 37 % fall of mitochondrial membrane potential, activation of caspase-9 and caspase-3 and mild activation of caspase-8 without any detectable apoptotic body formation in un-irradiated HsiI cells. We conclude that reduction of PARP-1 expression activates apoptotic signals via intrinsic and extrinsic pathways in un-irradiated cells. CIB irradiation further intensified both intrinsic and extrinsic pathways of apoptosis synergistically along with up-regulation of p53 in HsiI cells resulting overall higher apoptosis in HsiI than H-vector.

  8. 77 FR 31351 - Adequacy Determination for Aspen PM10 and Fort Collins Carbon Monoxide Maintenance Plans' Motor...

    Science.gov (United States)

    2012-05-25

    ... 93.118(e)(4), which was promulgated August 15, 1997 (62 FR 43780). We described our process for... (69 FR 40004). In addition, in certain areas with monitored ambient carbon monoxide (CO) values... AGENCY Adequacy Determination for Aspen PM and Fort Collins Carbon Monoxide Maintenance Plans'...

  9. Ion-beam technologies

    Energy Technology Data Exchange (ETDEWEB)

    Fenske, G.R. [Argonne National Lab., IL (United States)

    1993-01-01

    This compilation of figures and diagrams reviews processes for depositing diamond/diamond-like carbon films. Processes addressed are chemical vapor deposition (HFCVD, PACVD, etc.), plasma vapor deposition (plasma sputtering, ion beam sputtering, evaporation, etc.), low-energy ion implantation, and hybrid processes (biased sputtering, IBAD, biased HFCVD, etc.). The tribological performance of coatings produced by different means is discussed.

  10. Bond strength of short lap splices in RC beams confined with steel stirrups or external CFRP

    OpenAIRE

    Garcia, R.; Helal, Y.; Pilakoutas, K.; GUADAGNINI, M

    2015-01-01

    This paper investigates the bond behaviour of lapped steel bars using fifteen RC beams tested in flexure. Twelve of the beams were designed to fail by bond splitting at midspan, where the main flexural reinforcement was lapped 10 bar diameters. The parameters studied include the amount and type of confinement at midspan (no confinement, internal steel stirrups or externally bonded carbon FRP), concrete cover and bar size. The results show that the CFRP confinement enhanced the bond strength o...

  11. Beam characteristics of energy-matched flattening filter free beams

    Energy Technology Data Exchange (ETDEWEB)

    Paynter, D.; Weston, S. J.; Cosgrove, V. P. [St James Institute of Oncology The Leeds Teaching Hospitals NHS Trust, Medical Physics, Leeds LS9 7TF (United Kingdom); Evans, J. A. [LIGHT Institute University of Leeds Leeds LS2 9JT, Division of Medical Physics, Leeds (United Kingdom); Thwaites, D. I. [LIGHT Institute University of Leeds Leeds LS2 9JT, Division of Medical Physics, Leeds, United Kingdom and Institute of Medical Physics, School of Physics, University of Sydney (Australia)

    2014-05-15

    Purpose: Flattening filter free (FFF) linear accelerators can increase treatment efficiency and plan quality. There are multiple methods of defining a FFF beam. The Elekta control system supports tuning of the delivered FFF beam energy to enable matching of the percentage depth-dose (PDD) of the flattened beam at 10 cm depth. This is compared to FFF beams where the linac control parameters are identical to those for the flattened beam. All beams were delivered on an Elekta Synergy accelerator with an Agility multi-leaf collimator installed and compared to the standard, flattened beam. The aim of this study is to compare “matched” FFF beams to both “unmatched” FFF beams and flattened beams to determine the benefits of matching beams. Methods: For the three modes of operation 6 MV flattened, 6 MV matched FFF, 6 MV unmatched FFF, 10 MV flattened, 10 MV matched FFF, and 10 MV unmatched FFF beam profiles were obtained using a plotting tank and were measured in steps of 0.1 mm in the penumbral region. Beam penumbra was defined as the distance between the 80% and 20% of the normalized dose when the inflection points of the unflattened and flattened profiles were normalized with the central axis dose of the flattened field set as 100%. PDD data was obtained at field sizes ranging from 3 cm × 3 cm to 40 cm × 40 cm. Radiation protection measurements were additionally performed to determine the head leakage and environmental monitoring through the maze and primary barriers. Results: No significant change is made to the beam penumbra for FFF beams with and without PDD matching, the maximum change in penumbra for a 10 cm × 10 cm field was within the experimental error of the study. The changes in the profile shape with increasing field size are most significant for the matched FFF beam, and both FFF beams showed less profile shape variation with increasing depth when compared to flattened beams, due to consistency in beam energy spectra across the radiation field

  12. Efficacy and safety of 10,600-nm carbon dioxide fractional laser on facial skin with previous volume injections

    Directory of Open Access Journals (Sweden)

    Josiane Hélou

    2013-01-01

    Full Text Available Background: Fractionated carbon dioxide (CO 2 lasers are a new treatment modality for skin resurfacing. The cosmetic rejuvenation market abounds with various injectable devices (poly-L-lactic acid, polymethyl-methacrylate, collagens, hyaluronic acids, silicone. The objective of this study is to examine the efficacy and safety of 10,600-nm CO 2 fractional laser on facial skin with previous volume injections. Materials and Methods: This is a retrospective study including 14 patients treated with fractional CO 2 laser and who have had previous facial volume restoration. The indication for the laser therapy, the age of the patients, previous facial volume restoration, and side effects were all recorded from their medical files. Objective assessments were made through clinical physician global assessment records and improvement scores records. Patients′ satisfaction rates were also recorded. Results: Review of medical records of the 14 patients show that five patients had polylactic acid injection prior to the laser session. Eight patients had hyaluronic acid injection prior to the laser session. Two patients had fat injection, two had silicone injection and one patient had facial thread lift. Side effects included pain during the laser treatment, post-treatment scaling, post-treatment erythema, hyperpigmentation which spontaneously resolved within a month. Concerning the previous facial volume restoration, no granulomatous reactions were noted, no facial shape deformation and no asymmetry were encountered whatever the facial volume product was. Conclusion: CO 2 fractional laser treatments do not seem to affect facial skin which had previous facial volume restoration with polylactic acid for more than 6 years, hyaluronic acid for more than 0.5 year, silicone for more than 6 years, or fat for more than 1.4 year. Prospective larger studies focusing on many other variables (skin phototype, injected device type are required to achieve better

  13. Folate receptor-mediated boron-10 containing carbon nanoparticles as potential delivery vehicles for boron neutron capture therapy of nonfunctional pituitary adenomas.

    Science.gov (United States)

    Dai, Congxin; Cai, Feng; Hwang, Kuo Chu; Zhou, Yongmao; Zhang, Zizhu; Liu, Xiaohai; Ma, Sihai; Yang, Yakun; Yao, Yong; Feng, Ming; Bao, Xinjie; Li, Guilin; Wei, Junji; Jiao, Yonghui; Wei, Zhenqing; Ma, Wenbin; Wang, Renzhi

    2013-02-01

    Invasive nonfunctional pituitary adenomas (NFPAs) are difficult to completely resect and often develop tumor recurrence after initial surgery. Currently, no medications are clinically effective in the control of NFPA. Although radiation therapy and radiosurgery are useful to prevent tumor regrowth, they are frequently withheld because of severe complications. Boron neutron capture therapy (BNCT) is a binary radiotherapy that selectively and maximally damages tumor cells without harming the surrounding normal tissue. Folate receptor (FR)-targeted boron-10 containing carbon nanoparticles is a novel boron delivery agent that can be selectively taken up by FR-expressing cells via FR-mediated endocytosis. In this study, FR-targeted boron-10 containing carbon nanoparticles were selectively taken up by NFPAs cells expressing FR but not other types of non-FR expressing pituitary adenomas. After incubation with boron-10 containing carbon nanoparticles and following irradiation with thermal neutrons, the cell viability of NFPAs was significantly decreased, while apoptotic cells were simultaneously increased. However, cells administered the same dose of FR-targeted boron-10 containing carbon nanoparticles without neutron irradiation or received the same neutron irradiation alone did not show significant decrease in cell viability or increase in apoptotic cells. The expression of Bcl-2 was down-regulated and the expression of Bax was up-regulated in NFPAs after treatment with FR-mediated BNCT. In conclusion, FR-targeted boron-10 containing carbon nanoparticles may be an ideal delivery system of boron to NFPAs cells for BNCT. Furthermore, our study also provides a novel insight into therapeutic strategies for invasive NFPA refractory to conventional therapy, while exploring these new applications of BNCT for tumors, especially benign tumors.

  14. Laser ablation for the synthesis of carbon nanotubes

    Science.gov (United States)

    Holloway, Brian C. (Inventor); Eklund, Peter C. (Inventor); Smith, Michael W. (Inventor); Jordan, Kevin C. (Inventor); Shinn, Michelle (Inventor)

    2012-01-01

    Single walled carbon nanotubes are produced in a novel apparatus by the laser-induced ablation of moving carbon target. The laser used is of high average power and ultra-fast pulsing. According to various preferred embodiments, the laser produces and output above about 50 watts/cm.sup.2 at a repetition rate above about 15 MHz and exhibits a pulse duration below about 10 picoseconds. The carbon, carbon/catalyst target and the laser beam are moved relative to one another and a focused flow of "side pumped", preheated inert gas is introduced near the point of ablation to minimize or eliminate interference by the ablated plume by removal of the plume and introduction of new target area for incidence with the laser beam. When the target is moved relative to the laser beam, rotational or translational movement may be imparted thereto, but rotation of the target is preferred.

  15. Laser ablation for the synthesis of carbon nanotubes

    Science.gov (United States)

    Holloway, Brian C; Eklund, Peter C; Smith, Michael W; Jordan, Kevin C; Shinn, Michelle

    2012-11-27

    Single walled carbon nanotubes are produced in a novel apparatus by the laser-induced ablation of moving carbon target. The laser used is of high average power and ultra-fast pulsing. According to various preferred embodiments, the laser produces and output above about 50 watts/cm.sup.2 at a repetition rate above about 15 MHz and exhibits a pulse duration below about 10 picoseconds. The carbon, carbon/catalyst target and the laser beam are moved relative to one another and a focused flow of "side pumped", preheated inert gas is introduced near the point of ablation to minimize or eliminate interference by the ablated plume by removal of the plume and introduction of new target area for incidence with the laser beam. When the target is moved relative to the laser beam, rotational or translational movement may be imparted thereto, but rotation of the target is preferred.

  16. 预拉碳纤维布加固持荷混凝土梁受力性能分析%Mechanical Behavior of Pre-loaded Reinforced Concrete Beams Strengthened by Pre-tensioned Carbon Fiber Composite Sheets

    Institute of Scientific and Technical Information of China (English)

    高鹏; 顾祥林

    2009-01-01

    According to the characteristic of pre-loaded reinforced concrete beams strengthened by pre-tensioned carbon fiber composite sheets, a suitable finite element model and corresponding calculation steps were proposed. The method was verified by the testing results of two groups of strengthened beam specimens. Comparison between simulation and testing results shows that the proposed method is a precise numerical tool. Further parameter analysis using the proposed method shows that the bearing capacity of a strengthened beam might be notably reduced if the pre-load applied on the beam is larger than 40% of the initial bearing capacity of the beam, the strength of carbon fiber composite sheets can be fully used by using pre-tensioning technique,and the negative influence of the pre-load on the bending behavior of a strengthened beam can be made up when the pre-strain of carbon fiber composite sheets is between 0.003~0.004.%根据预张拉碳纤维布加固持荷钢筋混凝土梁受力特点,采用商业软件建立有限元模型对梁加固和受荷全过程进行模拟和分析.对两组试验梁的模拟计算结果显示,有限元方法有较好的精度.试验和进一步的有限元数值模拟分析结果表明,当构件上的持荷水平超过未加固构件承载力的40%时,持荷会降低加固构件的承载力;采用预张拉加固方法可充分发挥碳纤维布的强度,当碳纤维布中的有效预拉应变达0.003~0.004时,可消除持荷对加固梁受力性能的影响.

  17. Revealing the 1 nm/s Extensibility of Nanoscale Amorphous Carbon in a Scanning Electron Microscope

    DEFF Research Database (Denmark)

    Zhang, Wei

    2013-01-01

    In an ultra-high vacuum scanning electron microscope, the edged branches of amorphous carbon film (∼10 nm thickness) can be continuously extended with an eye-identifying speed (on the order of ∼1 nm/s) under electron beam. Such unusual mobility of amorphous carbon may be associated with deformation...

  18. Φ10mm 碳纤维复合材料管成型工艺及性能研究%Forming Process and Properties of Φ10 mm Carbon Fiber Reinforced Composite Pipe

    Institute of Scientific and Technical Information of China (English)

    赵锐霞; 尹亮; 潘玲英; 董波

    2012-01-01

    The forming process and properties of carbon fiber reinforced composite pipe with the diameter of 10mm were investigated. The results show that the carbon fiber reinforced composite pipe fabricated by the thermal shrinkage process has the advantages of simple forming process and better quality reliability. Compared to the stainless steel pipe with the diamemer of 10 mm, the carbon fiber reinforced composite pipe with the same diameter has the e-quivalent flexural stiffness. While the flexural strength of composite pipe is more than three times of the stainless steel with the same diameter, and its weight is only half of the stainless steel pipe. In addition, the composite has good dimension precision which can meet the design requirements.%对外径为Φ10 mm 碳纤维复合材料管成型工艺及性能进行了研究.结果表明,采用热缩工艺成型的碳纤维复合材料管工艺简单、质量可靠,Φ10 mm 碳纤维复合材料管件弯曲刚度与不锈钢管相当,弯曲强度为不锈钢的3倍以上,质量仅为不锈钢的50%,尺寸精度满足设计要求.

  19. Stable beams

    CERN Multimedia

    2015-01-01

    Stable beams: two simple words that carry so much meaning at CERN. When LHC page one switched from "squeeze" to "stable beams" at 10.40 a.m. on Wednesday, 3 June, it triggered scenes of jubilation in control rooms around the CERN sites, as the LHC experiments started to record physics data for the first time in 27 months. This is what CERN is here for, and it’s great to be back in business after such a long period of preparation for the next stage in the LHC adventure.   I’ve said it before, but I’ll say it again. This was a great achievement, and testimony to the hard and dedicated work of so many people in the global CERN community. I could start to list the teams that have contributed, but that would be a mistake. Instead, I’d simply like to say that an achievement as impressive as running the LHC – a machine of superlatives in every respect – takes the combined effort and enthusiasm of everyone ...

  20. Production of radioactive molecular beams for CERN-ISOLDE

    CERN Document Server

    AUTHOR|(SzGeCERN)703149; Kröll, Thorsten

    SOLDE, the Isotope Separation On-Line facility, at CERN is a leading facility for the production of beams of exotic radioactive isotopes. Currently over 1000 different isotopes with half lives down to milliseconds can be extracted with beam intensities of up to 10^11 ions per second. However, due to the reactive target environment not all isotopes are extractable in sufficient amounts. In this work the extraction of short lived carbon and boron isotopes is investigated. Therefore a variety of experimental and computanional techniques have been used.

  1. Production of radioactive molecular beams for CERN-ISOLDE

    Energy Technology Data Exchange (ETDEWEB)

    Seiffert, Christoph

    2015-06-15

    ISOLDE, the Isotope Separation On-Line facility, at CERN is a leading facility for the production of beams of exotic radioactive isotopes. Currently over 1000 different isotopes with half lives down to milliseconds can be extracted with beam intensities of up to 10{sup 11} ions per second. However, due to the reactive target environment not all isotopes are extractable in sufficient amounts. In this work the extraction of short lived carbon and boron isotopes is investigated. Therefore a variety of experimental and computational techniques have been used.

  2. Beam-monitors for TESLA based on diamond-strip-detectors

    CERN Document Server

    Bol, J; de Boer, Wim; Dierlamm, A; Grigoriev, E; Hauler, F; Jungermann, L

    2004-01-01

    For TESLA it's foreseen to measure the beam-profile with so called wire-scanners. A thin carbon fibre is moved through the beam and the number of scattered secondary particles is measured in correlation to the position. From that a beam-profile can be calculated as an average over many bunches of the beam. We successfully tested a diamond-detector in a heavy ion-beam with bunches of up to 3.10/sup 10/O/sup 6+/-ions and in a beam of 10/sup 10/ electrons, as planned for TESLA. The dose of 10/sup 15/e/sup -//cm/sup 2/ or more by one of the bunches foreseen for TESLA corresponds to the irradiation a vertex-detector receives during 10 years of LHC. With strip-detectors made from diamond the beam-profile can be measured online for single bunches, with more than one array of strips also for more than one direction. If fast electronics are used and bunches are not too short, even a longitudinal profile can be obtained. The results of our measurements will be presented and discussed afterwards.

  3. ULTRA LOW POWER SINGLE EDGE TRIGGERED DELAY FLIP FLOP BASED SHIFT REGISTERS USING 10-NANOMETER CARBON NANO TUBE FIELD EFFECT TRANSISTOR

    Directory of Open Access Journals (Sweden)

    Ravi Thiyagarajan

    2013-01-01

    Full Text Available Carbon Nano Tube Field Effect Transistor is currently considered as promising successor of Metal Oxide Semiconductor Field Effect Transistor. The scaling down of the Metal Oxide Semiconductor device faced serious limits like short channel effect, tunnelling through gate oxide layer, associated leakage currents and power dissipation when its dimension shrink down to 22 nanometer range. Further scaling of Metal Oxide Semiconductor Field Effect Transistor will result in performance degradation. In this study, an ultra low power Single Edge Triggered Delay Flip Flop and shift registers are designed using 10 nanometre Carbon Nano Tube Field Effect Transistor. The Carbon Nano Tube Field Effect Transistor is an efficient device to supplant the current Complementary Metal Oxide Semiconductor technology for its excellent electrical properties. The high electron and hole mobility of semiconductor nano tubes, their compatibility with high k gate dielectrics, enhanced electrostatics, reduced short channel effects and ability to readily form metal ohmic contacts make these miniaturized structures an ideal material for high performance, nanoscale transistors. To evaluate the performance of Ultra low power Single Edge Triggered Delay Flip Flop and shift registers using 10 nanometer Carbon Nano Tube Field Effect Transistor technology, the results are depicted by analyzing average power, delay, power delay product, rise time and fall time using HSPICE at 1GHz operating frequency.

  4. Carbon Fiber Laminate Strengthened RC Beams Subjected to Fatigue Loading at Elevated Temperature%温度升高对碳纤维薄板增强RC梁疲劳性能的影响

    Institute of Scientific and Technical Information of China (English)

    周芝林; 黄培彦; 郭馨艳

    2008-01-01

    The static and fatigue tests under cyclic bending loads at different ambient temperatures of 20 ℃ and 80℃ are carried out to investigate the fatigue behavior of the reinforced concrete(RC) beams strengthened with'carbon fi-ber laminates(CFLs). The failure modes of the strengthened beams include CFLs debonded near the mid-span and steel rebar yielded or broken. S-N curves of strengthened beams are developed according to the test results. The fa-tigue limit, load versus deflection curves and strain response of strengthened beams are obtained as well. The results show that the fatigue behaviors of the strengthened beams are not significantly influenced by the ambient tempera-tures (lower than 80℃) when the fatigue load levels equal 25.0 kN, 27.5 kN and 30.0 kN.%为了研究碳纤维薄板增强钢筋混凝土梁在不同温度下的疲劳性能,分别在20℃和80℃的温度条件下对26根增强梁进行了三点弯曲静载和疲劳试验.结果表明:当疲劳载荷水平为25.0 kN,27.5 kN和30.0 kN时,试件的S-N曲线、疲劳极限、破坏模式、挠度曲线和应变反映受环境温度的影响较小.

  5. Treatment of industrial effluents using electron beam accelerator and adsorption with activated carbon. A comparative study; Tratamento de efluentes industriais utilizando a radiacao ionizante de acelerador industrial de eletrons e por adsorcao com carvao ativado. Estudo comparativo

    Energy Technology Data Exchange (ETDEWEB)

    Las Casas, Alexandre

    2004-07-01

    Several methods are used In the pollutant removal from Industrial and domestic wastewater. However when the degradation of toxic organic pollutants, mainly the recalcitrant is objectified, the conventional treatments usually do not meet the desirable performance in the elimination or decrease the impact when the effluent are released to the environment what takes to the research of alternative methods that seek the improvement of the efficiency of the wastewater treatment systems jointly employees or separately. This work presents a study of degradation/removal of pollutants organic compounds comparing two methods using radiation from industrial electron beam and granular activated carbon (GAC). The removal efficiency of the pollutants was evaluated and it was verified that the efficiency of adsorption with activated carbon is similar to the radiation method. The obtained results allowed to evaluated the relative costs of these methods. (author)

  6. Fast ignition by quasimonoenergetic ion beams

    Directory of Open Access Journals (Sweden)

    Honrubia J.J.

    2013-11-01

    Full Text Available The potential of quasimonoenergetic ion beams for fast ignition (FI of fusion targets is investigated. Lithium, carbon, aluminium and vanadium ions have been considered here to determine the optimal kinetic energy for each ion type. Our calculations show that the ignition energies of those beams impinging on a standard fuel configuration are similar. However, they are obtained for very different ion energies. Assuming that the ions can be focused onto 10 μm spots, a new irradiation scheme that reduces substantially the ignition energies is proposed. The combination of using intermediate ions, such as 5.5 GeV vanadium, and the new irradiation scheme allows one to reduce the number of ions required for ignition by roughly three orders of magnitude when compared with the standard proton FI scheme.

  7. Radiocarbon based source apportionment of black carbon in the form of PM10 elemental carbon aerosol particles at the Zeppelin Observatory, Svalbard

    Science.gov (United States)

    Winiger, Patrik; Andersson, August; Espen Yttri, Karl; Tunved, Peter; Gustafsson, Örjan

    2015-04-01

    Black carbon (BC) aerosol particles are formed from incomplete combustion of fossil fuel and biomass. Transported into the Arctic, they potentially contributes to climate warming. However, there are still large uncertainties related to the climate effects of BC, including aspects of radiative properties, mixing state of the particles, transport, atmospheric lifetime and sources. The current study aims to reduce source uncertainties by applying a top-down (observational) source-diagnostic isotope approach and comparing these to bottom-up (modeling) emission inventories to better constrain the source types and source regions. The use of natural abundance radiocarbon (Δ14C) is a powerful tool to distinguish between fossil (void of 14C) and biomass (contemporary 14C) combustion sources. Due to the well-defined end-members, 14C-measurements (alone) provide high precision (

  8. Beam - cavity interaction beam loading

    International Nuclear Information System (INIS)

    The interaction of a beam with a cavity and a generator in cyclic accelerators or storage rings is investigated. Application of Maxwell's equations together with the nonuniform boundary condition allows one to get an equivalent circuit for a beam-loaded cavity. The general equation for beam loading is obtained on the basis of the equivalent circuit, and the beam admittance is calculated. Formulas for power consumption by a beam-loaded cavity are derived, and the optimal tuning and coupling factor are analyzed. (author)

  9. Relativistic electron beams above thunderclouds

    DEFF Research Database (Denmark)

    Füellekrug, M.; Roussel-Dupre, R.; Symbalisty, E. M. D.;

    2011-01-01

    Non-luminous relativistic electron beams above thunderclouds have been detected by the radio signals of low frequency similar to 40-400 kHz which they radiate. The electron beams occur similar to 2-9 ms after positive cloud-to-ground lightning discharges at heights between similar to 22-72 km above...... thunderclouds. Intense positive lightning discharges can also cause sprites which occur either above or prior to the electron beam. One electron beam was detected without any luminous sprite which suggests that electron beams may also occur independently of sprites. Numerical simulations show that beams...... of electrons partially discharge the lightning electric field above thunderclouds and thereby gain a mean energy of similar to 7MeV to transport a total charge of similar to-10mC upwards. The impulsive current similar to 3 x 10(-3) Am-2 associated with relativistic electron beams above thunderclouds...

  10. Kevlar and Carbon Fiber Sheet Reinforced Soil Reinforced Concrete Beam Flexural Performance Test Inquiry%碳纤维布及芳纶布加固钢筋混土梁受弯性能试验探究

    Institute of Scientific and Technical Information of China (English)

    邝美玲

    2016-01-01

    在土木工程建设中,碳纤维布及芳纶布为钢筋混土构件带来了新的加固机遇,已成为工程施工中的实质性保障,占据着综合比例的重要地位。基于此,从钢筋混土梁入手,结合相关试验案例,重点分析碳纤维布及芳纶布加固钢筋混土梁受弯性能的优化举措,以供相关研究参考。%In the civil engineering construction,carbon fiber and Kevlar fiber cloth cloth reinforced concrete soil reinforcement member has brought new opportunities,construction has become a substantive guarantee,occupies an important position integrated scale.Based on this,the soil from reinforced concrete beams,combining relevant test case focuses on Kevlar Reinforced with carbon fiber sheet reinforced concrete and soil beam flexural performance optimization initiatives for research reference.

  11. Beam loading

    CERN Document Server

    Gamp, Alexander

    2013-01-01

    We begin by giving a description of the radio-frequency generator-cavity-beam coupled system in terms of basic quantities. Taking beam loading and cavity detuning into account, expressions for the cavity impedance as seen by the generator and as seen by the beam are derived. Subsequently methods of beam-loading compensation by cavity detuning, radio-frequency feedback and feedforward are described. Examples of digital radio-frequency phase and amplitude control for the special case of superconducting cavities are also given. Finally, a dedicated phase loop for damping synchrotron oscillations is discussed.

  12. Radiation curing of carbon fibre composites

    Science.gov (United States)

    Spadaro, G.; Alessi, S.; Dispenza, C.; Sabatino, M. A.; Pitarresi, G.; Tumino, D.; Przbytniak, G.

    2014-01-01

    Epoxy/carbon fibre reinforced composites were produced by means of e-beam irradiation through a pulsed 10 MeV electron beam accelerator. The matrix consisted of a difunctional epoxy monomer (DGEBA) and an initiator of cationic polymerisation, while the reinforcement was a unidirectional high modulus carbon fibre fabric. Dynamic mechanical thermal analysis was carried out in order to determine the cross-linking degree. The analysis pointed out a nonuniformity in the cross-linking degree of the e-beam cured panels, with the formation of clusters at low Tg (glass transition temperature) and clusters at high Tg. An out-of-mould post irradiation thermal treatment on e-beam cured samples provides a higher uniformity in the network although some slight degradation effects. Mode I delamination fracture toughness and Interlaminar Shear Strength (ISS) were also investigated by means of Double Cantilever Beam (DCB) and Short Beam Shear tests, respectively. Results from this mechanical characterisation allowed to correlate fracture toughness of the bulk matrix resin, cross-linking density and fibre/matrix interaction to the delamination fracture behaviour of the fibre reinforced material.

  13. First storage of ion beams in the Double Electrostatic Ion-Ring Experiment: DESIREE

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, H. T.; Thomas, R. D.; Gatchell, M.; Rosen, S.; Reinhed, P.; Loefgren, P.; Braennholm, L.; Blom, M.; Bjoerkhage, M.; Baeckstroem, E.; Alexander, J. D.; Leontein, S.; Zettergren, H.; Liljeby, L.; Kaellberg, A.; Simonsson, A.; Hellberg, F.; Mannervik, S.; Larsson, M.; Geppert, W. D. [Department of Physics, Stockholm University, SE-10691 Stockholm (Sweden); and others

    2013-05-15

    We report on the first storage of ion beams in the Double ElectroStatic Ion Ring ExpEriment, DESIREE, at Stockholm University. We have produced beams of atomic carbon anions and small carbon anion molecules (C{sub n}{sup -}, n= 1, 2, 3, 4) in a sputter ion source. The ion beams were accelerated to 10 keV kinetic energy and stored in an electrostatic ion storage ring enclosed in a vacuum chamber at 13 K. For 10 keV C{sub 2}{sup -} molecular anions we measure the residual-gas limited beam storage lifetime to be 448 s {+-} 18 s with two independent detector systems. Using the measured storage lifetimes we estimate that the residual gas pressure is in the 10{sup -14} mbar range. When high current ion beams are injected, the number of stored particles does not follow a single exponential decay law as would be expected for stored particles lost solely due to electron detachment in collision with the residual-gas. Instead, we observe a faster initial decay rate, which we ascribe to the effect of the space charge of the ion beam on the storage capacity.

  14. First fringes with an integrated-optics beam combiner at 10 um - A new step towards instrument miniaturization for mid-infrared interferometry

    CERN Document Server

    Labadie, Lucas; Anheier, Norman C; Arezki, Brahim; Qiao, H A; Bernacki, Bruce; Kern, Pierre

    2011-01-01

    Observations at mas-resolution scales and high dynamic range hold a central place in achieving, for instance, the spectroscopic characterization of exo-Earths or the detailed mapping of their protoplanetary disc birthplace. Ground or space-based multi-aperture infrared interferometry is a promising technique to tackle these goals. But significant efforts still need to be undertaken to achieve a simplification of these instruments if we want to combine the light from a large number of telescopes. Integrated-optics appears as an alternative to the current conventional designs, especially if its use can be extended to a higher number of astronomical bands. This article reports for the first time the experimental demonstration of the feasibility of an integrated-optics approach to mid-infrared beam combination for single-mode stellar interferometry. We have fabricated a 2-telescope beam combiner prototype integrated on a substrate of chalcogenide glasses, a material transparent from 1 to 14 um. We have developed ...

  15. Paramagnetic centers in single-walled carbon nanotubes encapsulated with palladium and their interaction with hydrogen at H/C ≥ 1.0

    Science.gov (United States)

    Lipson, A. G.; Saunin, E. I.; Lyakhov, B. F.; Tsivadze, A. Yu.

    2008-10-01

    The nature of paramagnetic centers in a nanostructure based on single-walled carbon nanotubes (SWCNTs) encapsulated with Pd was studied by EPR spectroscopy at 77 and 293 K. It was found that strong charge-transfer π complexes of the (Pd-C x ) type, which manifested themselves as a narrow resonance (Δ H = 6 8 G and g = 2.002 at T = 77 k), were formed in the Pd-SWCNT composite along with impurity centers (Fe3O4 nanoparticles within the nanotubes), which were responsible for a broad EPR signal (Δ H = 75 G and g = 2.065 at T = 293 K). These complexes were found to be predominant adsorption sites responsible for a high gravimetric density of hydrogen (H/C ≥ 1.0) within the single-walled carbon nanotubes.

  16. Air pollution studies in terms of PM2.5, PM2.5-10, PM10, lead and black carbon in urban areas of Antananarivo - Madagascar

    CERN Document Server

    Rasoazanany, E O; Ravoson, H N; Andriambololona, Raoelina; Randriamanivo, L V; Ramaherison, H; Ahmed, H; Harinoely, M

    2012-01-01

    Atmospheric aerosols or particulate matters are chemically complex and dynamic mixtures of solid and liquid particles. Sources of particulate matters include both natural and anthropogenic processes. The present work consists in determining the concentrations of existing elements in the aerosols collected in Andravoahangy and in Ambodin'Isotry in Antananarivo city (Madagascar). The size distribution of these elements and their main sources are also studied. The Total Reflection X-Ray Fluorescence spectrometer is used for the qualitative and quantitative analyses. The results show that the concentrations of the airborne particulate matters PM2.5-10 are higher than those of PM2.5. The identified elements in the aerosol samples are Ti, Cr, Mn, Fe, Ni, Cu, Zn, Br, Sr and Pb. The average concentrations of these elements are also higher in the coarse particles than in the fine particles. The calculation of the enrichment factors by Mason's model shows that Cr, Ni, Cu, Zn, Br and Pb are of anthropogenic origins. The...

  17. SU-E-I-10: Investigation On Detectability of a Small Target for Different Slice Direction of a Volumetric Cone Beam CT Image

    Energy Technology Data Exchange (ETDEWEB)

    Lee, C; Han, M; Baek, J [Yonsei University, Incheon (Korea, Republic of)

    2015-06-15

    Purpose: To investigate the detectability of a small target for different slice direction of a volumetric cone beam CT image and its impact on dose reduction. Methods: Analytic projection data of a sphere object (1 mm diameter, 0.2/cm attenuation coefficient) were generated and reconstructed by FDK algorithm. In this work, we compared the detectability of the small target from four different backprojection Methods: hanning weighted ramp filter with linear interpolation (RECON 1), hanning weighted ramp filter with Fourier interpolation (RECON2), ramp filter with linear interpolation (RECON 3), and ramp filter with Fourier interpolation (RECON4), respectively. For noise simulation, 200 photons per measurement were used, and the noise only data were reconstructed using FDK algorithm. For each reconstructed volume, axial and coronal slice were extracted and detection-SNR was calculated using channelized Hotelling observer (CHO) with dense difference-of-Gaussian (D-DOG) channels. Results: Detection-SNR of coronal images varies for different backprojection methods, while axial images have a similar detection-SNR. Detection-SNR{sup 2} ratios of coronal and axial images in RECON1 and RECON2 are 1.33 and 1.15, implying that the coronal image has a better detectability than axial image. In other words, using coronal slices for the small target detection can reduce the patient dose about 33% and 15% compared to using axial slices in RECON 1 and RECON 2. Conclusion: In this work, we investigated slice direction dependent detectability of a volumetric cone beam CT image. RECON 1 and RECON 2 produced the highest detection-SNR, with better detectability in coronal slices. These results indicate that it is more beneficial to use coronal slice to improve detectability of a small target in a volumetric cone beam CT image. This research was supported by the MSIP (Ministry of Science, ICT and Future Planning), Korea, under the IT Consilience Creative Program (NIPA-2014-H0201

  18. THE MECHANICAL BEHAVIOR EXPERIMENT AND ANALYSIS OF CONTINUOUS BEAMS STRENGTHENED WITH CARBON FIBER REINFORCED POLYMER SHEETS%碳纤维布加固连续梁力学性能试验及分析

    Institute of Scientific and Technical Information of China (English)

    程东辉; 王天峰; 易亚敏

    2011-01-01

    为了开展碳纤维布加固钢筋混凝土连续梁受力性能的研究工作,对3根两跨采用碳纤维布加固的钢筋混凝土连续梁进行三分点加载的受力性能试验研究,获得加固状态下钢筋混凝土连续梁正截面承载力、裂缝分布及开展、中支座塑性铰区分布长度等试验实测值和荷载-挠度曲线及内力重分布关系曲线。试验研究表明:钢筋混凝土连续梁在加固状态下的破坏呈现中支座纵向受力钢筋先屈服,跨中纵向受力钢筋后屈服,碳纤维布被拉断的形式;试验梁加载过程中有明显的内力重分布,承载力极限状态下内力重分布幅度超过50%;由于跨中碳纤维布的存在约束了连续梁的变形,从而导致中支座控制截面附近塑性区域分布长度比普通钢筋混凝土连续梁有所减小。%In order to study the mechanical behavior of concrete continuous beams strengthened with CFRP sheets, 3 two-span continuous beams were fabricated, and strengthened with CFRP sheets at each span. The test of loading on two-point was completed, from which the bearing capacity, cracks distribution, the test value of the length of plastic hinge region, curves of load-deformation and curves of internal force redistribution were obtained. The test results showed that the failure of concrete continuous beams strengthened with CFRP sheets was characterized by longtitudinal reinforcement yielded in intermediate support sections, then the longtitudinal reinforcement yielded in the middle span sections, at last carbon fiber polymer sheets were pulled off. The internal force redistribution appeared apparently in beams during loading process and the redistribution rate was over 50% in the state of ultimate bearing capacity. As CFRP confined the deflection of beams,the length of the plastic hinge region near the sections of intermediate support was reduced as compared to ordinary continuous reinforced beams.

  19. Comparing microbial and chemical approaches for modelling soil organic carbon decomposition using the DecoChem v1.0 and DecoBio v1.0 models

    Directory of Open Access Journals (Sweden)

    G. Xenakis

    2014-01-01

    Full Text Available Soil organic matter is a vast store of carbon, with a critical role in the global carbon cycle. Despite its importance the dynamics of soil organic carbon decomposition, under the impact of climate change or changing litter inputs, are poorly understood. Current biogeochemical models usually lack microbial processes and thus miss an important feedback when considering the fate of carbon. Here we use a series of modelling experiments to evaluate two different model structures, one with a standard first order kinetic representation of soil decomposition (DecoChem v1.0, hearafter chemical model and one with control of soil decomposition through microbial activity (DecoBio v1.0, hereafter biological model. We tested two hypotheses. First, that increased litter inputs and glucose addition prime microbial activity and reduce soil carbon stocks in the biological model, but increase C stocks in the chemical model. Experiments provided some support for this hypothesis, with soil C stocks increasing in the chemical model in response to litter increases. In the biological model, responses to changed litter quantity were more rapid, but with the residence time of soil C altering such that soil C stocks were buffered. However, in the biological model there was a strong response to increased glucose additions (i.e., changes in litter quality, with significant losses to soil C stocks over time, driven by priming. Secondly, we hypothesised that warming will stimulate decomposition in the chemical model, and loss of C, but in the biological model soil C will be less sensitive to warming, due to complex microbial feedbacks. The experiments supported this hypothesis, with the chemical model soil C residence times and steady state C stocks adjusting strongly with temperature changes, extending over decades. On the other hand, the biological model showed a rapid response to temperature that subsided after a few years, with total soil C stocks largely unchanged. The

  20. Effect of C–O Bonding on the Stability and Energetics of High-Energy Nitrogen-Carbon Molecules N10C2 and N16C2

    Directory of Open Access Journals (Sweden)

    Douglas L. Strout

    2014-01-01

    Full Text Available Molecules consisting of nitrogen have been the subject of much attention due to their potential as high-energy materials. Complex molecules consisting entirely of nitrogen can be subject to rapid decomposition, and therefore other atoms are incorporated into the structure to enhance stability. Previous studies have explored the incorporation of carbon atoms into otherwise all-nitrogen cages molecules. The current study involves two such cages, N10C2 and N16C2, whose structures are derived from N12 and N18, respectively. The N10C2 and N16C2 cages in this study are modified by bonding groups O3 and CO3 to determine the effect on the relative energies between the isomers and on the thermodynamic energy release properties. Energetic trends for N10C2 and N16C2 are calculated and discussed.

  1. 碳纤维加固钢-混凝土组合梁承载力极限状态计算%Analysis of Ultimate Load-carrying Capacity of Strengthening Steel-concrete Composite Beam Using Carbon Fiber

    Institute of Scientific and Technical Information of China (English)

    荣学亮; 黄侨

    2011-01-01

    Carbon fiber is a kind of optimal materials for bridge maintenance and reinforcement. Design method of strengthening steel-concrete composite bridges using carbon fiber was studied. Characteristic of bridge reinforce-ment under load and phasing of stress features were considered, and calculation method of ultimate limit state was suitable for existing bridge design code . Ultimate strain of carbon fiber in ultimate limit state is firstly established based on plane-section assumption and strain-lag of carbon fiber. Then computational scheme and calculation meth-od of flexural capacity in positive moment area and negative moment area for strengthening steel-concrete composite beam using carbon fiber are established respectively, which is reference for design of bridge strengthening.%碳纤维复合材料是进行桥梁维修和加固的理想材料.对采用碳纤维复合材料加固钢-混凝土组合梁桥的设计方法进行了分析.考虑桥梁结构带载加固分阶段受力的特点,与现行桥梁设计规范中承载能力极限状态计算方法相适应.首先基于平截面假设和碳纤维应变滞后的特点,确定承载能力极限状态下碳纤维片材的极限应变值.然后分别建立了碳纤维片材加固钢-混凝土组合梁在正弯矩区和负弯矩区抗弯承载力的计算图式和计算方法,可供桥梁加固工程设计参考.

  2. Effect of carbon content on carbide morphology and mechanical properties of A.R. white cast iron with 10-12% tungsten

    Energy Technology Data Exchange (ETDEWEB)

    Heydari, D. [Department of Materials Science and Engineering, Sharif University of Technology, Tehran (Iran, Islamic Republic of); Skandani, A. Alipour [Department of Engineering Science and Mechanics, Virginia Tech, Blacksburg, VA 24061 (United States); Al Haik, M., E-mail: alhaik@vt.edu [Department of Engineering Science and Mechanics, Virginia Tech, Blacksburg, VA 24061 (United States)

    2012-04-30

    Highlights: Black-Right-Pointing-Pointer Effect of W and C variation in A.R. white cast iron was studied up to 12 wt% W. It never exceeded 10 wt% in previous investigations. Black-Right-Pointing-Pointer Carbide morphologies with 2.2-3.2 wt% carbon shows that W has dominating effect on carbide morphology. Black-Right-Pointing-Pointer New carbide microstructures (GA and IA) appear in some range of carbon and its volume fraction is function of carbon content. Black-Right-Pointing-Pointer After heat treatment, new carbide morphology turns to continuous chromium carbide. Black-Right-Pointing-Pointer Wear resistance and hardness of the new alloys depends on both IA appearance presence and tungsten carbide precipitation. - Abstract: Carbide morphologies of white cast iron containing 22% Cr and 10-12% tungsten with different carbon contents (2.34-3.20 wt.%) were investigated. Results indicated that for the as-cast alloys with no heat treatments, the addition of carbon changes the morphology of carbides during air-cooling in the presence of tungsten. Light microscopy analysis revealed that for an alloy with 2.3 wt% carbon, chromium carbides possess coarse gray appearance (GA). Increasing the carbon content reduced the coarse GA zones volume fraction while a finer GA zones emerged. The coexistence of coarse and fine GA phases came to an end at 2.8 wt% carbon, at which only fine GA zones spread throughout the chromium carbide phase. Scaling up the carbon content to 3.2 wt% led to the formation of tungsten carbide and austenite in a eutectic reaction. Both fine and coarse GA zones vanished while the tungsten carbides acquired fishbone-like morphology. Upon heat treatment, the coarse GA zones vanished completely and turned into island appearance (IA) of chromium carbide. On the contrary, the finer GA zones remained unchanged after heat treatment and they coexisted with the IA. After heat treatment, the fishbone morphology shattered apart, however, the hyper chromium carbides

  3. Beam Instabilities

    CERN Document Server

    Rumolo, G

    2014-01-01

    When a beam propagates in an accelerator, it interacts with both the external fields and the self-generated electromagnetic fields. If the latter are strong enough, the interplay between them and a perturbation in the beam distribution function can lead to an enhancement of the initial perturbation, resulting in what we call a beam instability. This unstable motion can be controlled with a feedback system, if available, or it grows, causing beam degradation and loss. Beam instabilities in particle accelerators have been studied and analysed in detail since the late 1950s. The subject owes its relevance to the fact that the onset of instabilities usually determines the performance of an accelerator. Understanding and suppressing the underlying sources and mechanisms is therefore the key to overcoming intensity limitations, thereby pushing forward the performance reach of a machine.

  4. Three-dimensional dose-rate distribution of X-ray beams of linac neptun 10p and gamma-rays from Co-60 gammatron 80S for rectangular fields.

    Science.gov (United States)

    Lobodziec, W; Lambrinow, N; Stala, T; Kośniewski, W

    1981-05-01

    A method of calculation of the three-dimensional dose-rate distribution for X-rays of Linac Neptun 10p and gamma-rays of Gamma-tron 80S is presented. The experimental results show that the profiles function defined as the relative dose-rate across the radiation beam is useful for this purpose, and it is sufficient to determine the profile function only at one depth and for one field size. The results of measurements are presented on the graphs. PMID:7245280

  5. Relativistic electron beams above thunderclouds

    Directory of Open Access Journals (Sweden)

    M. Füllekrug

    2011-05-01

    Full Text Available Non-luminous relativistic electron beams above thunderclouds are detected by radio remote sensing with low frequency radio signals from 40–400 kHz. The electron beams occur 2–9 ms after positive cloud-to-ground lightning discharges at heights between 22–72 km above thunderclouds. The positive lightning discharges also cause sprites which occur either above or before the electron beam. One electron beam was detected without any luminous sprite occurrence which suggests that electron beams may also occur independently. Numerical simulations show that the beamed electrons partially discharge the lightning electric field above thunderclouds and thereby gain a mean energy of 7 MeV to transport a total charge of 10 mC upwards. The impulsive current associated with relativistic electron beams above thunderclouds is directed downwards and needs to be considered as a novel element of the global atmospheric electric circuit.

  6. Changes in Belowground Carbon Cycling After 10 Years at the Duke Free-Air CO2 Enrichment (FACE) Experiment

    Science.gov (United States)

    Jackson, R. B.; Cook, C. W.; Pippen, J. S.

    2006-05-01

    Carbon dioxide concentrations are increasing rapidly in the earth's atmosphere and have risen by a third since the start of the industrial revolution. Beginning in 1996, the Duke Free-Air CO2 Enrichment (FACE) experiment has exposed a loblolly pine forest to an additional 200 parts per million CO2 (high CO2 treatment) compared to trees at ambient CO2. Root biomass has increased significantly at high CO2, as have soil respiration and the concentration of CO2 in the soil at different depths. Peak changes for root biomas, soil respiration, and many other variables occur in mid summer, with responses diminishing or disappearing in winter. This presentation will review the changes over the first decade of the experiment, emphasizing results from the most recent three years.

  7. Heat of Mixing and Solution of Dimethyl sulfoxide C2H6OS + C5H10O3 Diethyl carbonate (HMSD1111, LB4315_H)

    Science.gov (United States)

    Cibulka, I.; Fontaine, J.-C.; Sosnkowska-Kehiaian, K.; Kehiaian, H. V.

    This document is part of Subvolume C 'Binary Liquid Systems of Nonelectrolytes III' of Volume 26 'Heats of Mixing, Vapor-Liquid Equilibrium, and Volumetric Properties of Mixtures and Solutions' of Landolt-Börnstein Group IV 'Physical Chemistry'. It contains the Chapter 'heat of Mixing and Solution of Dimethyl sulfoxide C2H6OS + C5H10O3 Diethyl carbonate (HMSD1111, LB4315_H)' providing data from direct low-pressure calorimetric measurement of molar excess enthalpy at variable mole fraction and constant temperature.

  8. Volumetric Properties of the Mixture Dimethyl sulfoxide C2H6OS + C5H10O3 Diethyl carbonate (VMSD1111, LB5134_V)

    Science.gov (United States)

    Cibulka, I.; Fontaine, J.-C.; Sosnkowska-Kehiaian, K.; Kehiaian, H. V.

    This document is part of Subvolume C 'Binary Liquid Systems of Nonelectrolytes III' of Volume 26 'Heats of Mixing, Vapor-Liquid Equilibrium, and Volumetric Properties of Mixtures and Solutions' of Landolt-Börnstein Group IV 'Physical Chemistry'. It contains the Chapter 'Volumetric Properties of the Mixture Dimethyl sulfoxide C2H6OS + C5H10O3 Diethyl carbonate (VMSD1111, LB5134_V)' providing data from direct low-pressure measurement of mass density at variable mole fraction and constant temperature, in the single-phase region(s).

  9. Volumetric Properties of the Mixture Dimethyl sulfoxide C2H6OS + C5H10O3 Diethyl carbonate (VMSD1212, LB5137_V)

    Science.gov (United States)

    Cibulka, I.; Fontaine, J.-C.; Sosnkowska-Kehiaian, K.; Kehiaian, H. V.

    This document is part of Subvolume C 'Binary Liquid Systems of Nonelectrolytes III' of Volume 26 'Heats of Mixing, Vapor-Liquid Equilibrium, and Volumetric Properties of Mixtures and Solutions' of Landolt-Börnstein Group IV 'Physical Chemistry'. It contains the Chapter 'Volumetric Properties of the Mixture Dimethyl sulfoxide C2H6OS + C5H10O3 Diethyl carbonate (VMSD1212, LB5137_V)' providing data by calculation of molar excess volume from low-pressure density measurements at variable mole fraction and constant temperature.

  10. Definition of Beam Diameter for Electron Beam Welding

    International Nuclear Information System (INIS)

    It is useful to characterize the dimensions of the electron beam during process development for electron beam welding applications. Analysis of the behavior of electron beam welds is simplest when a single number can be assigned to the beam properties that describes the size of the beam spot; this value we generically call the 'beam diameter'. This approach has worked well for most applications and electron beam welding machines with the weld dimensions (width and depth) correlating well with the beam diameter. However, in recent weld development for a refractory alloy, Ta-10W, welded with a low voltage electron beam machine (LVEB), it was found that the weld dimensions (weld penetration and weld width) did not correlate well with the beam diameter and especially with the experimentally determined sharp focus point. These data suggest that the presently used definition of beam diameter may not be optimal for all applications. The possible reasons for this discrepancy and a suggested possible alternative diameter definition is the subject of this paper.

  11. Definition of Beam Diameter for Electron Beam Welding

    Energy Technology Data Exchange (ETDEWEB)

    Burgardt, Paul [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pierce, Stanley W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dvornak, Matthew John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-03-11

    It is useful to characterize the dimensions of the electron beam during process development for electron beam welding applications. Analysis of the behavior of electron beam welds is simplest when a single number can be assigned to the beam properties that describes the size of the beam spot; this value we generically call the “beam diameter”. This approach has worked well for most applications and electron beam welding machines with the weld dimensions (width and depth) correlating well with the beam diameter. However, in recent weld development for a refractory alloy, Ta-10W, welded with a low voltage electron beam machine (LVEB), it was found that the weld dimensions (weld penetration and weld width) did not correlate well with the beam diameter and especially with the experimentally determined sharp focus point. These data suggest that the presently used definition of beam diameter may not be optimal for all applications. The possible reasons for this discrepancy and a suggested possible alternative diameter definition is the subject of this paper.

  12. Ultrafast Beam Switching Using Coupled VCSELs

    Science.gov (United States)

    Ning, Cun-Zheng; Goorjian, Peter

    2001-01-01

    We propose a new approach to performing ultrafast beam switching using two coupled Vertical-Cavity Surface-Emitting Lasers (VCSELs). The strategy is demonstrated by numerical simulation, showing a beam switching of 10 deg at 42 GHz.

  13. 9,10-Dibromo-N-aryl-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-diones: Synthesis and Investigation of Their Effects on Carbonic Anhydrase Isozymes I, II, IX, and XII.

    Science.gov (United States)

    Göksu, Haydar; Topal, Meryem; Keskin, Ali; Gültekin, Mehmet S; Çelik, Murat; Gülçin, İlhami; Tanc, Muhammet; Supuran, Claudiu T

    2016-06-01

    N-substituted maleimides were synthesized from maleic anhydride and primary amines. 1,4-Dibromo-dibenzo[e,h]bicyclo-[2,2,2]octane-2,3-dicarboximide derivatives (4a-f) were prepared by the [4+2] cycloaddition reaction of dibromoanthracenes with the N-substituted maleimide derivatives. The carbonic anhydrase (CA, EC 4.2.1.1) inhibitory effects of the new derivatives were assayed against the human (h) isozymes hCA I, II, IX, and XII. All tested bicyclo dicarboximide derivatives exhibited excellent inhibitory effects in the nanomolar range, with Ki values in the range of 117.73-232.87 nM against hCA I and of 69.74-111.51 nM against hCA II, whereas they were low micromolar inhibitors against hCA IX and XII. PMID:27174792

  14. The silicate and carbon-rich models of CoRoT-7b, Kepler-9d and Kepler-10b

    Institute of Scientific and Technical Information of China (English)

    Yan-Xiang Gong; Ji-Lin Zhout

    2012-01-01

    Possible bulk compositions of the super-Earth exoplanets CoRoT-7b,Kepler-9d,and Kepler-10b are investigated by applying a commonly used silicate model and a non-standard carbon model.Their internal structures are deduced using a suitable equation of state for the materials.The degeneracy problems of their compositions can be partly overcome,based on the fact that all three planets are extremely close to their host stars.By analyzing the numerical results,we conclude:1) the iron core of CoRoT-7b is not more than 27% of its total mass within lσ mass-radius error bars,so an Earth-like composition is less likely,but its carbon rich model can be compatible with an Earth-like core/mantle mass fraction; 2) Kepler-10b is more likely to have a Mercury-like composition,with its old age implying that its high iron content may be a result of strong solar wind or giant impact; 3) the transiting-only super-Earth Kepler-9d is also discussed.Combining its possible composition with the formation theory,we can place some constraints on its mass and bulk composition.

  15. Beam collimator

    CERN Multimedia

    1977-01-01

    A four-block collimator installed on a control table for positioning the alignment reference marks. Designed for use with SPS secondary beams, the collimator operates under vacuum conditions. See Annual Report 1976 p. 121 and photo 7701014.

  16. Changing Rule of Carbon-Enriched Zone and Diffusion Behavior of Carbon in Aging 0Cr6Mn13Ni10MoTi/1Cr5Mo Dissimilar Welded Joints

    Institute of Scientific and Technical Information of China (English)

    Zheng LIU; Ligang WANG; Lai WANG

    2004-01-01

    The microstructures, the changing rule of carbon-enriched zone, the diffusion behaviors of elements C and Cr, and the carbide type of 0Cr6Mn13Ni10MoTi/1Cr5Mo dissimilar welded joints after aging at 500℃ for various times and after long-term service in technical practice were investigated by using the optical microscopy, electron probe microanalysis, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The results show that in aging 0Cr6Mn13Ni10MoTi/1Cr5Mo dissimilar welded joints, the main carbides are M3C and a few carbides are M7C3 and M23C6. The M3C carbide decomposition and dissolution with increasing aging time or aging temperature and the anti-diffusion of C and Cr cause the decrease and disappearance of the carbon-enriched zone. The results are different from those of the A302/1Cr5Mo dissimilar welded joints in previous studies.

  17. Exhaustive Analysis of a Genotype Space Comprising 10(15 )Central Carbon Metabolisms Reveals an Organization Conducive to Metabolic Innovation.

    OpenAIRE

    Sayed-Rzgar Hosseini; Aditya Barve; Andreas Wagner

    2015-01-01

    All biological evolution takes place in a space of possible genotypes and their phenotypes. The structure of this space defines the evolutionary potential and limitations of an evolving system. Metabolism is one of the most ancient and fundamental evolving systems, sustaining life by extracting energy from extracellular nutrients. Here we study metabolism's potential for innovation by analyzing an exhaustive genotype-phenotype map for a space of 10(15) metabolisms that encodes all possible su...

  18. Preparation of self-supporting carbon thin films

    CERN Document Server

    Lommel, B; Kindler, B; Klemm, J; Steiner, J

    2002-01-01

    For heavy-ion beam experiments, self-supporting carbon thin films are needed as targets, stripper foils and as backings (Nucl. Instr. and Meth. A 334 (1993) 69) for materials which cannot be produced self-supporting. Using resistance evaporation under high vacuum, self-supporting carbon foils with a thickness of 5 mu g/cm sup 2 and a diameter of 10 mm, a thickness of 10 mu g/cm sup 2 and a diameter of 50 mm up to a thickness of 50 mu g/cm sup 2 and a diameter of 300 mm can be obtained. Due to the energy impact of the heavy-ion beam, the amorphous carbon is restructured into textured graphite, as was found already by Dollinger et al. (Nucl. Instr. and Meth. A 303 (1991) 79). The discuss the production process as well as the change of the layer structure caused by the energy deposit.

  19. 再生混凝土梁截面碳化深度分布的计算分析%Analysis on the Distribution of Carbonation Depth across the Section of Recycled Aggregate Concrete Beams

    Institute of Scientific and Technical Information of China (English)

    雷斌; 饶春华; 扶名福; 晏育松

    2015-01-01

    首先,将裂缝弥散化并将裂缝的影响耦合到再生混凝土中 CO2的扩散系数中,基于 Fick 定律建立受力状态下再生混凝土中 CO2扩散方程,根据质量守恒定律,推导出考虑应力状态影响时再生混凝土中 CO2的传质方程;然后,通过加速碳化试验,确定了传质方程中应力水平影响系数的大小;最后,采用 MATLAB 编制有限元程序求解传质方程,确定了再生混凝土梁截面的碳化深度分布。结果表明,对于顶面不传质的再生混凝土梁,截面上的碳化深度分布很不均匀,受压区角部再生混凝土碳化深度最小,而受拉区角部再生混凝土的碳化深度最大,其值为受压区一般边再生混凝土碳化深度的2.2倍,为相应的无应力状态下同配比普通混凝土梁一般边的2.4倍。%Firstly,cracks were dispersed and their influence was included in the coefficient of CO2 diffusion, and based on the Fick’s law,the equation of CO2 diffusion was established,and according to the hypothesis that the process of CO2 diffusion complied with the principle of mass transfer,the equation of mass convec-tion was finally derived in which the effect of stress was included;Then,the value of the stress influence-factor associated with the CO2 diffusion was obtained by conducting the accelerated carbonation tests;Fi-nally,Substituting the value of the stress influence-factor associated with the CO2 diffusion into the mass convection equation and using a finite element program developed by the author with MATLAB to solve this equation,the distribution of the carbonation depth across the section of recycled aggregate concrete beams in the service-state was determined.The results showed that,for the recycled aggregate concrete beam of which the top surface had no CO2 mass transfer,the distribution of carbonation depth at section was very uneven,carbonation depth in the corner of compression zone was minimal,while the

  20. Calcium carbonate as a possible dosimeter for high irradiation doses

    Energy Technology Data Exchange (ETDEWEB)

    Negron M, A.; Ramos B, S.; Camargo R, C. [UNAM, Instituto de Ciencias Nucleares, Ciudad Universitaria, 04510 Mexico D. F. (Mexico); Uribe, R. M. [Kent State University, College of Technology, Kent OH (United States); Gomez V, V. [UNAM, Instituto de Quimica, Ciudad Universitaria, 04510 Mexico D. F. (Mexico); Kobayashi, K., E-mail: negron@nucleares.unam.mx [Yokohama National University (Japan)

    2014-08-15

    The aim of this work is to analyze the interactions of 5 MeV electron beam radiation and a 290 MeV/u Carbon beam with calcium carbonate (powder) at 298 K and at different irradiation doses, for the potential use of calcium carbonate as a high-dose dosimeter. The irradiation doses with the electron beam were from 0.015 to 9 MGy, and with Carbon beam from 1.5 kGy to 8 kGy. High-energy radiation induces the formation of free radicals in solid calcium carbonate that can be detected and measured by electron paramagnetic resonance (EPR). An increase of the EPR response for some of the free radicals produced in the sample was observed as a function of the irradiation dose. The response of one of the radicals decreased with the dose. These measurements are reproducible; the preparation of the sample is simple and inexpensive; and the signal is stable for several months. The response curves show that the dosimeter tends to saturate at 10 MGy. Based on these properties, we propose this chemical compound as a high-dose dosimeter, mainly for electron irradiation. (author)

  1. Sex Differences in Panic-Relevant Responding to a 10% Carbon Dioxide-Enriched Air Biological Challenge

    OpenAIRE

    Nillni, Yael I.; Berenz, Erin C.; Kelly J. Rohan; Zvolensky, Michael J.

    2011-01-01

    The current study examined sex differences in psychological (i.e., self-reported anxiety, panic symptoms, and avoidance) and physiological (i.e., heart rate and skin conductance level) response to, and recovery from, a laboratory biological challenge. Participants were a community-recruited sample of 128 adults (63.3% women; Mage = 23.2 years, SD = 8.9) who underwent a 4-minute 10% CO2-enriched air biological challenge. As predicted, women reported more severe physical panic symptoms and avoi...

  2. P-23 Highlights 6/10/12: Cygnus Dual Beam Radiographic Facility Refurbishment completed at U1A tunnel in Nevada NNSS meeting Level 2 milestone

    Energy Technology Data Exchange (ETDEWEB)

    Deyoung, Anemarie [Los Alamos National Laboratory; Smith, John R. [Los Alamos National Laboratory

    2012-05-03

    A moratorium was placed on U.S. underground nuclear testing in 1992. In response, the Stockpile Stewardship Program was created to maintain readiness of the existing nuclear inventory through several efforts such as computer modeling, material analysis, and subcritical nuclear experiments (SCEs). As in the underground test era, the Nevada National Security Site (NNSS), formerly the Nevada Test Site, provides a safe and secure environment for SCEs by the nature of its isolated and secure facilities. A major tool for SCE diagnosis installed in the 05 drift laboratory is a high energy x-ray source used for time resolved imaging. This tool consists of two identical sources (Cygnus 1 and Cygnus 2) and is called the Cygnus Dual Beam Radiographic Facility (Figs. 2-6). Each Cygnus machine has 5 major elements: Marx Generator, Pulse Forming Line (PFL), Coaxial Transmission Line (CTL), 3-cell Inductive Voltage Adder (IVA), and Rod Pinch Diode. Each machine is independently triggered and may be fired in separate tests (staggered mode), or in a single test where there is submicrosecond separation between the pulses (dual mode). Cygnus must operate as a single shot machine since on each pulse the diode electrodes are destroyed. The diode is vented to atmosphere, cleaned, and new electrodes are inserted for each shot. There is normally two shots per day on each machine. Since its installation in 2003, Cygnus has participated in: 4 Subcritical Experiments (Armando, Bacchus, Barolo A, and Barolo B), a 12 shot plutonium physics series (Thermos), and 2 plutonium step wedge calibration series (2005, 2011), resulting in well over 1000 shots. Currently the Facility is in preparation for 2 SCEs scheduled for this calendar year - Castor and Pollux. Cygnus has performed well during 8 years of operations at NNSS. Many improvements in operations and performance have been implemented during this time. Throughout its service at U1a, major maintenance and replacement of many hardware items

  3. P-23 Highlights 6/10/12: Cygnus Dual Beam Radiographic Facility Refurbishment completed at U1A tunnel in Nevada NNSS meeting Level 2 milestone

    International Nuclear Information System (INIS)

    A moratorium was placed on U.S. underground nuclear testing in 1992. In response, the Stockpile Stewardship Program was created to maintain readiness of the existing nuclear inventory through several efforts such as computer modeling, material analysis, and subcritical nuclear experiments (SCEs). As in the underground test era, the Nevada National Security Site (NNSS), formerly the Nevada Test Site, provides a safe and secure environment for SCEs by the nature of its isolated and secure facilities. A major tool for SCE diagnosis installed in the 05 drift laboratory is a high energy x-ray source used for time resolved imaging. This tool consists of two identical sources (Cygnus 1 and Cygnus 2) and is called the Cygnus Dual Beam Radiographic Facility (Figs. 2-6). Each Cygnus machine has 5 major elements: Marx Generator, Pulse Forming Line (PFL), Coaxial Transmission Line (CTL), 3-cell Inductive Voltage Adder (IVA), and Rod Pinch Diode. Each machine is independently triggered and may be fired in separate tests (staggered mode), or in a single test where there is submicrosecond separation between the pulses (dual mode). Cygnus must operate as a single shot machine since on each pulse the diode electrodes are destroyed. The diode is vented to atmosphere, cleaned, and new electrodes are inserted for each shot. There is normally two shots per day on each machine. Since its installation in 2003, Cygnus has participated in: 4 Subcritical Experiments (Armando, Bacchus, Barolo A, and Barolo B), a 12 shot plutonium physics series (Thermos), and 2 plutonium step wedge calibration series (2005, 2011), resulting in well over 1000 shots. Currently the Facility is in preparation for 2 SCEs scheduled for this calendar year - Castor and Pollux. Cygnus has performed well during 8 years of operations at NNSS. Many improvements in operations and performance have been implemented during this time. Throughout its service at U1a, major maintenance and replacement of many hardware items

  4. Compact electron beam focusing column

    Energy Technology Data Exchange (ETDEWEB)

    Persaud, Arun; Leung, Ka-Ngo; Reijonen, Jani

    2001-07-13

    A novel design for an electron beam focusing column has been developed at LBNL. The design is based on a low-energy spread multicusp plasma source which is used as a cathode for electron beam production. The focusing column is 10 mm in length. The electron beam is focused by means of electrostatic fields. The column is designed for a maximum voltage of 50 kV. Simulations of the electron trajectories have been performed by using the 2-D simulation code IGUN and EGUN. The electron temperature has also been incorporated into the simulations. The electron beam simulations, column design and fabrication will be discussed in this presentation.

  5. Infrared imaging diagnostics for INTF ion beam

    Science.gov (United States)

    Sudhir, D.; Bandyopadhyay, M.; Pandey, R.; Joshi, J.; Yadav, A.; Rotti, C.; Bhuyan, M.; Bansal, G.; Soni, J.; Tyagi, H.; Pandya, K.; Chakraborty, A.

    2015-04-01

    In India, testing facility named INTF [1] (Indian test facility) is being built in Institute for Plasma Research to characterize ITER-Diagnostic Neutral Beam (DNB). INTF is expected to deliver 60A negative hydrogen ion beam current of energy 100keV. The beam will be operated with 5Hz modulation having 3s ON/20s OFF duty cycle. To characterize the beam parameters several diagnostics are at different stages of design and development. One of them will be a beam dump, made of carbon fiber composite (CFC) plates placed perpendicular to the beam direction at a distance lm approximately. The beam dump needs to handle ˜ 6MW of beam power with peak power density ˜ 38.5MW/m2. The diagnostic is based on thermal (infra-red - IR) imaging of the footprint of the 1280 beamlets falling on the beam dump using four IR cameras from the rear side of the dump. The beam dump will be able to measure beam uniformity, beamlet divergence. It may give information on relative variation of negative ion stripping losses for different beam pulses. The design of this CFC based beam dump needs to address several physics and engineering issues, including some specific inputs from manufacturers. The manuscript will describe an overview of the diagnostic system and its design methodology highlighting those issues and the present status of its development.

  6. Sci—Sat AM: Stereo — 08: Stereotactic Ablative Radiotherapy (SABR) for low, intermediate and high risk prostate cancer using Volumetric Modulated Arc Therapy (VMAT) with a 10x Flattening Filter Free (FFF) beam

    Energy Technology Data Exchange (ETDEWEB)

    Mestrovic, A; Fortin, D; Alexander, A [BC Cancer Agency - Vancouver Island Centre (Canada)

    2014-08-15

    Purpose: To determine the feasibility of using Volumetric Modulated Arc Therapy (VMAT) with a 10x Flattening Filter Free (FFF) beam for Stereotactic Ablative Radiotherapy (SABR) for low, intermediate and high risk prostate cancer. Methods and Materials: Ten anonymized patient CT data sets were used in this planning study. For each patient CT data set, three sets of contours were generated: 1) low risk, 2) intermediate risk, and 3) high risk scenarios. For each scenario, a single-arc and a double-arc VMAT treatment plans were created. Plans were generated with the Varian Eclipse™ treatment planning system for a Varian TrueBeam™ linac equipped with Millenium 120 MLC. Plans were created using a 10x-FFF beam with a maximum dose rate of 2400 MU/min. Dose prescription was 36.25Gy/5 fractions with the planning objective of covering 99% of the Planning Target Volume with the 95% of the prescription dose. Normal tissue constraints were based on provincial prostate SABR planning guidelines, derived from national and international prostate SABR protocols. Plans were evaluated and compared in terms of: 1) dosimetric plan quality, and 2) treatment delivery efficiency. Results: Both single-arc and double-arc VMAT plans were able to meet the planning goals for low, intermediate and high risk scenarios. No significant dosimetric differences were observed between the plans. However, the treatment time was significantly lower for a single-arc VMAT plans. Conclusions: Prostate SABR treatments are feasible with 10x-FFF VMAT technique. A single-arc VMAT offers equivalent dosimetric plan quality and a superior treatment delivery efficiency, compared to a double-arc VMAT.

  7. Compact and high-particle-flux thermal-lithium-beam probe system for measurement of two-dimensional electron density profile.

    Science.gov (United States)

    Shibata, Y; Manabe, T; Kajita, S; Ohno, N; Takagi, M; Tsuchiya, H; Morisaki, T

    2014-09-01

    A compact and high-particle-flux thermal-lithium-beam source for two-dimensional measurement of electron density profiles has been developed. The thermal-lithium-beam oven is heated by a carbon heater. In this system, the maximum particle flux of the thermal lithium beam was ~4 × 10(19) m(-2) s(-1) when the temperature of the thermal-lithium-beam oven was 900 K. The electron density profile was evaluated in the small tokamak device HYBTOK-II. The electron density profile was reconstructed using the thermal-lithium-beam probe data and this profile was consistent with the electron density profile measured with a Langmuir electrostatic probe. We confirm that the developed thermal-lithium-beam probe can be used to measure the two-dimensional electron density profile with high time and spatial resolutions.

  8. An integrated Dissolved Organic Carbon Dynamics Model (DOCDM 1.0: model development and a case study in the Alaskan Yukon River Basin

    Directory of Open Access Journals (Sweden)

    X. Lu

    2015-12-01

    Full Text Available Quantitative understanding of the variation in dissolved organic carbon (DOC is important to studying the terrestrial ecosystem carbon cycle. This study presents a process-based, dissolved organic carbon dynamics model (DOCDM 1.0 that couples the soil heat conduction, water flow, DOC production, mineralization and transport in both surface and subsurface of soil profile to quantify DOC dynamics in boreal terrestrial ecosystems. The model is first evaluated and then applied for a watershed in Alaska to investigate its DOC production and transport. We find that 42 and 27 % of precipitation infiltrates to soils in 2004, a warmer year, and in 1976, a colder year, respectively. Under warming conditions, DOC transported via overland flow does not show the expected decrease trend while the overland DOC yield shows a 4 % increase. The horizontal subsurface flow only accounts for 1–2 % of total water flux, but transports 30–50 % of DOC into rivers. Water flush due to water infiltration controls DOC transport. Snowmelt plays a noticeable role in DOC flush-out and DOC transport significantly depends on flowpaths in the study region. High soil temperature stimulates DOC production. The overland DOC export does not necessarily follow the DOC downward trend in surface water transport. Overall, this study shows that DOC export behavior is complex under changing temperature and hydrological conditions in cold-region watersheds. To adequately quantify DOC dynamics in northern high latitudes, more DOC and hydrological data are needed to better parameterize and test the developed model before extrapolating it to the region.

  9. Bombardment of SiC by 10 keV H+: carbon deposition, surface swelling and changes in surface morphology

    International Nuclear Information System (INIS)

    SiC surfaces were bombarded by H+ at 10 keV to total doses ranging from 0.7 to 25 C/cm2 in both high and ultra high vacuum environments. In the former, carbonaceous deposits were observed optically and with AES and electron microprobe analysis. The thickness of these deposits (determined by surface profilometry) increased up to a dose of 3 C/cm2 then remained constant. Surface features were observed on these deposits using SEM. In UHV, no deposit was formed, however surface swelling was observed. Surface features were again observed but were qualitatively different than those observed on the carbonaceous deposits. Several possible explanations for these observations are discussed including, in the case of the carbonaceous deposits, a possible phase change from amorphous to ordered occurring in the vicinity of a 3 C/cm2 dose. (Auth.)

  10. In-beam test of the Boron-10 Multi-Grid neutron detector at the IN6 time-of-flight spectrometer at the ILL

    International Nuclear Information System (INIS)

    A neutron detector concept based on solid layers of boron carbide enriched in 10B has been in development for the last few years as an alternative for 3He by collaboration between the ILL, ESS and Linköping University. This Multi-Grid detector uses layers of aluminum substrates coated with 10B4C on both sides that are traversed by the incoming neutrons. Detection is achieved using a gas counter readout principle. By segmenting the substrate and using multiple anode wires, the detector is made inherently position sensitive. This development is aimed primarily at neutron scattering instruments with large detector areas, such as time-of-flight chopper spectrometers. The most recent prototype has been built to be interchangeable with the 3He detectors of IN6 at ILL. The 10B detector has an active area of 32 x 48cm2. It was installed at the IN6 instrument and operated for several weeks, collecting data in parallel with the regularly scheduled experiments, thus providing the first side-by-side comparison with the conventional 3He detectors. Results include an efficiency comparison, assessment of the in-detector scattering contribution, sensitivity to gamma-rays and the signal-to-noise ratio in time-of-flight spectra. The good expected performance has been confirmed with the exception of an unexpected background count rate. This has been identified as natural alpha activity in aluminum. New convertor substrates are under study to eliminate this source of background.

  11. Energy Loss of High Intensity Focused Proton Beams Penetrating Metal Foils

    Science.gov (United States)

    McGuffey, C.; Qiao, B.; Kim, J.; Beg, F. N.; Wei, M. S.; Evans, M.; Fitzsimmons, P.; Stephens, R. B.; Chen, S. N.; Fuchs, J.; Nilson, P. M.; Canning, D.; Mastrosimone, D.; Foord, M. E.

    2014-10-01

    Shortpulse-laser-driven intense ion beams are appealing for applications in probing and creating high energy density plasmas. Such a beam isochorically heats and rapidly ionizes any target it enters into warm dense matter with uncertain transport and stopping properties. Here we present experimental measurements taken with the 1.25 kJ, 10 ps OMEGA EP BL shortpulse laser of the proton and carbon spectra after passing through metal foils. The laser irradiated spherically curved C targets with intensity 4×1018 W/cm2, producing proton beams with 3 MeV slope temperature and a sharp low energy cutoff at 5 MeV which has not been observed on lower energy, shorter pulse intense lasers. The beam either diverged freely or was focused to estimated 1016 p +/cm2 ps by a surrounding structure before entering the metal foils (Al or Ag and a Cu tracer layer). The proton and ion spectra were altered by the foil depending on material and whether or not the beam was focused. Transverse proton radiography probed the target with ps temporal and 10 micron spatial resolution, indicating an electrostatic field on the foil may also have affected the beam. We present complementary particle-in-cell simulations of the beam generation and transport to the foils. This work was supported by the DOE/NNSA National Laser User Facility program, Contract DE-SC0001265.

  12. Use of the mar-lin criteria to determine the influence of porosity on the iosipescu and short beam shear properties in carbon fiber polymer matrix composites

    OpenAIRE

    Antonio Carlos Ancelotti Junior; Luiz Claudio Pardini; Eduardo Marcelo Bezerra; Dennis Roach

    2010-01-01

    To address a critical aspect of the fast growing use of composites in aircraft and aerospace industry, the influence of the porosity on the shear strength of composites property was investigated as a mean for determining the critical values of porosity. Acid digestion techniques were applied to determine the void volume ratio of two families of carbon epoxy laminates (8 and 16 plies). Ultrasonic inspections revealed the corresponding attenuation coefficients. The void morphology was investiga...

  13. From carbon nanotubes to carbon atomic chains

    Science.gov (United States)

    Casillas García, Gilberto; Zhang, Weijia; José-Yacamán, Miguel

    2010-10-01

    Carbyne is a linear allotrope of carbon. It is formed by a linear arrangement of carbon atoms with sp-hybridization. We present a reliable and reproducible experiment to obtain these carbon atomic chains using few-layer-graphene (FLG) sheets and a HRTEM. First the FLG sheets were synthesized from worm-like exfoliated graphite and then drop-casted on a lacey-carbon copper grid. Once in the TEM, two holes are opened near each other in a FLG sheet by focusing the electron beam into a small spot. Due to the radiation, the carbon atoms rearrange themselves between the two holes and form carbon fibers. The beam is concentrated on the carbon fibers in order excite the atoms and induce a tension until multi wall carbon nanotube (MWCNT) is formed. As the radiation continues the MWCNT breaks down until there is only a single wall carbon nanotube (SWCNT). Then, when the SWCNT breaks, an atomic carbon chain is formed, lasts for several seconds under the radiation and finally breaks. This demonstrates the stability of this carbon structure.

  14. Charge stripping of U238 ion beam by helium gas stripper

    Science.gov (United States)

    Imao, H.; Okuno, H.; Kuboki, H.; Yokouchi, S.; Fukunishi, N.; Kamigaito, O.; Hasebe, H.; Watanabe, T.; Watanabe, Y.; Kase, M.; Yano, Y.

    2012-12-01

    Development of a nondestructive, efficient electric-charge-stripping method is a key requirement for next-generation high-intensity heavy-ion accelerators such as the RIKEN Radioactive-Isotope Beam Factory. A charge stripper employing a low-Z gas is an important candidate applicable to high-intensity uranium beams for replacing carbon-foil strippers. In this study, a high-beam-transmission charge-stripping system employing helium gas for U238 beams injected at 10.8MeV/u was developed and demonstrated for the first time. The charge-state evolution measured using helium in a thickness range of 0.24-1.83mg/cm2 is compared with theoretical predictions. Energy attenuation and energy spread due to the helium stripper are also investigated.

  15. Precision shape modification of nanodevices with a low-energy electron beam

    Science.gov (United States)

    Zettl, Alex; Yuzvinsky, Thomas David; Fennimore, Adam

    2010-03-09

    Methods of shape modifying a nanodevice by contacting it with a low-energy focused electron beam are disclosed here. In one embodiment, a nanodevice may be permanently reformed to a different geometry through an application of a deforming force and a low-energy focused electron beam. With the addition of an assist gas, material may be removed from the nanodevice through application of the low-energy focused electron beam. The independent methods of shape modification and material removal may be used either individually or simultaneously. Precision cuts with accuracies as high as 10 nm may be achieved through the use of precision low-energy Scanning Electron Microscope scan beams. These methods may be used in an automated system to produce nanodevices of very precise dimensions. These methods may be used to produce nanodevices of carbon-based, silicon-based, or other compositions by varying the assist gas.

  16. First principle study of magnetic and electronic properties of single X (X = Al, Si) atom added to small carbon clusters (C n X, n = 2-10)

    Science.gov (United States)

    Afshar, M.; Hoseini, S. S.; Sargolzaei, M.

    2016-07-01

    In this paper, the magnetic and electronic properties of single aluminum and silicon atom added to small carbon clusters (C n X; X = Al, Si; n = 2-10) are studied in the framework of generalized-gradient approximation using density functional theory. The calculations were performed for linear, two dimensional and three dimensional clusters based on full-potential local-orbital (FPLO) method. The total energies, HOMO-LUMO energy gap and total magnetic moments of the most stable structures are presented in this work. The calculations show that C n Si clusters have more stability compared to C n Al clusters. In addition, our magnetic calculations were shown that the C n Al isomers are magnetic objects whereas C n Si clusters are nonmagnetic objects.

  17. Carbon steel protection in G.S. (Girlder sulfide) heavy water fabrication plants. Control of iron content at the final stage of passivation. Pt. 10

    International Nuclear Information System (INIS)

    This paper is part of a series which corresponds to the carbon steel behaviour as construction material for Girlder sulfide (G.S.) heavy water plants. The present work analyses the iron concentration study during passivation in the passivating fluid. At the beginning, during the formation of the most soluble sulfide -that is the mackinawite-, the iron concentration reaches more than 10 ppm. After some days, this iron concentration begins to decrease up to its stabilization under 0.1 ppm. This process, which occurs in the 9th. and 11th days, indicates that passivation is over, and that a pyrite and pyrrhotite-pyrite layer exists on the iron. Some differences exist between the results obtained and those previsible for the iron sulfides solubilities. In spite of these difficulties, the procedure is perfectly adequate to judge the passivation final stage. (Author)

  18. An rf electron beam buncher

    International Nuclear Information System (INIS)

    A method is described for producing density modulations on an intense relativistic electron beam by the use of rf fields in a betatron configuration. In concept, a device embodying this method should be capable of producing short (1-10 ns) electron bunches from a long (10-100 ns) beam, and is expected to be relatively compact and to operate efficiently on low power and energy. The method requires that the azimuthal phase velocity of the rf wave equal the electron beam velocity. Depending on phase relative to the rf wave, electrons in the beam gain or lose energy and form bunches by the negative mass effect. The dynamics of the electrons in the combined rf wave and betatron field have been analyzed. An example of an rf electron beam buncher is given

  19. Cold and Slow Molecular Beam

    CERN Document Server

    Lu, Hsin-I; Wright, Matthew J; Patterson, Dave; Doyle, John M

    2011-01-01

    Employing a two-stage cryogenic buffer gas cell, we produce a cold, hydrodynamically extracted beam of calcium monohydride molecules with a near effusive velocity distribution. Beam dynamics, thermalization and slowing are studied using laser spectroscopy. The key to this hybrid, effusive-like beam source is a "slowing cell" placed immediately after a hydrodynamic, cryogenic source [Patterson et al., J. Chem. Phys., 2007, 126, 154307]. The resulting CaH beams are created in two regimes. One modestly boosted beam has a forward velocity of vf = 65 m/s, a narrow velocity spread, and a flux of 10^9 molecules per pulse. The other has the slowest forward velocity of vf = 40 m/s, a longitudinal temperature of 3.6 K, and a flux of 5x10^8 molecules per pulse.

  20. Beam emittance measurements in RHIC

    Energy Technology Data Exchange (ETDEWEB)

    Zelenski,A.; Bazilevsky, A.; Bunce, G.; Gill, R.; Huang, H.; Makdisi, Y.; Morozov, B.; Nemesure, S.; Russo, t.; Steski, D.; Sivertz, M.

    2009-05-04

    The RHIC proton polarimeters can operate in scanning mode, giving polarization profiles and transverse beam intensity profile (beam emittance) measurements. The polarimeters function as wire scanners, providing a very good signal/noise ratio and high counting rate. This allows accurate bunch-by-bunch emittance measurements during fast target sweeps (<1 s) through the beam. Very thin carbon strip targets make these measurements practically non-destructive. Bunch by bunch emittance measurements are a powerful tool for machine set-up; in RHIC, individual proton beam transverse emittances can only be measured by CNI polarimeter scans. We discuss the consistency of these measurements with Ionization Profile Monitors (IPMs) and vernier scan luminosity measurements. Absolute accuracy limitations and cross-calibration of different techniques are also discussed.

  1. Novel chemoresistive CH{sub 4} sensor with 10 ppm sensitivity based on multiwalled carbon nanotubes functionalized with SnO{sub 2} nanocrystals

    Energy Technology Data Exchange (ETDEWEB)

    Humayun, Md Tanim; Paprotny, Igor, E-mail: paprotny@uic.edu [Department of Electrical and Computer Engineering, University of Illinois, Chicago, Illinois 60607 (United States); Divan, Ralu; Liu, Yuzi [Center for Nanoscale Materials, Argonne National Laboratory, Lemont, Illinois 60439 (United States); Gundel, Lara [Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Solomon, Paul A. [U.S. Environmental Protection Agency, Las Vegas, Nevada 89199 (United States)

    2016-01-15

    Chemoresistive sensors based on multiwalled carbon nanotubes (MWCNTs) functionalized with SnO{sub 2} nanocrystals (NCs) have great potential for detecting trace gases at low concentrations (single ppm levels) at room temperature, because the SnO{sub 2} nanocrystals act as active sites for the chemisorption of gas molecules, and carbon nanotubes (CNTs) act as an excellent current carrying platform, allowing the adsorption of gas on SnO{sub 2} to modulate the resistance of the CNTs. However, uniform conjugation of SnO{sub 2} NCs with MWCNTs is challenging. An effective atomic layer deposition based approach to functionalize the surface of MWCNTs with SnO{sub 2} NCs, resulting in a novel CH{sub 4} sensor with 10 ppm sensitivity, is presented in this paper. Scanning electron microscopy, transmission electron microscopy (TEM), energy dispersive x-ray spectroscopy, and Raman spectroscopy were implemented to study the morphology, elemental composition, and the crystal quality of SnO{sub 2} functionalized MWCNTs. High resolution TEM images showed that the crystal quality of the functionalizing SnO{sub 2} NCs was of high quality with clear lattice fringes and the dimension almost three times smaller than shown thus far in literature. A lift-off based photolithography technique comprising bilayer photoresists was optimized to fabricate SnO{sub 2} functionalized MWCNTs-based chemoresistor sensor, which at room temperature can reliably sense below 10 ppm of CH{sub 4} in air. Such low level gas sensitivity, with significant reversible relative resistance change, is believed to be the direct result of the successful functionalization of the MWCNT surface by SnO{sub 2} NCs.

  2. Novel chemoresistive CH4 sensor with 10 ppm sensitivity based on multiwalled carbon nanotubes functionalized with SnO2 nanocrystals

    International Nuclear Information System (INIS)

    Chemoresistive sensors based on multiwalled carbon nanotubes (MWCNTs) functionalized with SnO2 nanocrystals (NCs) have great potential for detecting trace gases at low concentrations (single ppm levels) at room temperature, because the SnO2 nanocrystals act as active sites for the chemisorption of gas molecules, and carbon nanotubes (CNTs) act as an excellent current carrying platform, allowing the adsorption of gas on SnO2 to modulate the resistance of the CNTs. However, uniform conjugation of SnO2 NCs with MWCNTs is challenging. An effective atomic layer deposition based approach to functionalize the surface of MWCNTs with SnO2 NCs, resulting in a novel CH4 sensor with 10 ppm sensitivity, is presented in this paper. Scanning electron microscopy, transmission electron microscopy (TEM), energy dispersive x-ray spectroscopy, and Raman spectroscopy were implemented to study the morphology, elemental composition, and the crystal quality of SnO2 functionalized MWCNTs. High resolution TEM images showed that the crystal quality of the functionalizing SnO2 NCs was of high quality with clear lattice fringes and the dimension almost three times smaller than shown thus far in literature. A lift-off based photolithography technique comprising bilayer photoresists was optimized to fabricate SnO2 functionalized MWCNTs-based chemoresistor sensor, which at room temperature can reliably sense below 10 ppm of CH4 in air. Such low level gas sensitivity, with significant reversible relative resistance change, is believed to be the direct result of the successful functionalization of the MWCNT surface by SnO2 NCs

  3. Breeding pleuromutilin protoplasts strains by carbon ion beam irradiation%碳离子束辐照选育截短侧耳素菌原生质体

    Institute of Scientific and Technical Information of China (English)

    都雯玥; 陆锡宏; 李雪虎; 周翔; 梁剑平; 辛志君

    2016-01-01

    使用12C6+离子束辐照Clitopilus pinsitus原生质体至不同吸收剂量,运用琼脂柱预筛和96孔板固体发酵选育截短侧耳素高产变异株.结果显示,最佳12C6+离子束吸收剂量为1.5 Gy,在该吸收剂量下正变异率为37.58%.选育出C.pin15Ⅰ5E和C.pin15Ⅱ6B两株正变异株,其产量较出发菌株分别提高16.17%和15.47%.表明重离子束辐照原生质体是行之有效的工业微生物诱变育种方法.%Clitopilus pinsitusprotoplast was irradiated by12C6+ion beam at varied absorbed doses for mutagenesis, and high-yielding pleuromutilin mutant strains were screened using high-throughput method and solid fermentation. The results showed that the optimum12C6+ ion beam absorbed dose is 1.5 Gy, and under this condition the positive mutation rate is 37.58%. By agar column prescreening and 96-plate solid fermentation, the mutant strains, C.pin15Ⅰ5E and C.pin15Ⅱ6B, were selected. The yields of the strain increased by 16.17% and 15.47%, respectively, compared with that of the original strain. The research suggests that applying heavy ion irradiation to protoplast is a possible method to breed mutant strains.

  4. Turn-By Beam Extraction during Acceleration in a Synchrotron

    Science.gov (United States)

    Tsoupas, Nicholaos; Trbojevic, Dejan

    2014-02-01

    A synchrotron to accelerate protons or carbon ions for medical applications is being designed at Brookhaven National Laboratory (BNL). Single beam bunches with maximum beam energy of 1.18 GeV and 400 MeV/u for protons and carbon ions respectively will be extracted from the synchrotron at 15 Hz. For protons, the maximum required energy for irradiating a tumor is ˜206 MeV. A pencil-like proton beam containing ˜5.4×107 p/bunch delivers a therapeutic dose of 2.5 Gy in ˜1.5 minutes to treat a tumor of 1 liter volume. It will take ˜80 minutes with bunches containing 4.5×104 ions/bunch to deliver the same dose of 2.5 Gy with a 400 MeV/u pencil-like carbon beam. This extended treatment time when using carbon ions is not acceptable. In addition, the synchrotron cannot be controlled with a beam bunch containing such a low number of carbon ions. To overcome these two problems of the extended treatment time and the low bunch intensity required for the treatment when carbon ions are used, we have devised a method to “peel” the required 4.5×104 carbon-ions/bunch from the accelerating carbon beam bunch containing ˜108 ions/bunch and deliver them to the tumor on a “turn-by-turn” basis. Unlike other methods of beam extraction from a synchrotron, such as resonance extraction, this method does not allow for any beam losses during the extraction and the carbon beam can be peeled off in less than 15 ms during the acceleration or deceleration cycle of the synchrotron. Thus, this turn-by-turn beam extraction method provides beam with variable energy and precisely controlled beam current during the 30 ms acceleration or deceleration time.

  5. Status of Design of PEFP Beam Lines

    Energy Technology Data Exchange (ETDEWEB)

    Park, Bum Sik; Cho, Yong Sub; Kwon, Hyeok Jung; Jang, Ji Ho; Hong, In Seok; Kim, Han Sung; Yun, Sang Pil; Lee, Hwa Ryun; Kim, Kye Ryung; Choi, Byung Ho [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2009-10-15

    PEFP(Proton Engineering Frontier Project) is developing a high current 100MeV proton linear accelerator. 20MeV and 100MeV proton beam lines are also under development for beam applications. 10 beam lines will be developed to support various purposes. Two kind of proton beam energy will be transported to 2 beamlines for industrial applications and 3 beamlines for various researches. The characteristic design scheme of PEFP beam lines is the application of a programmable AC magnet. Beam distribution to 3 research beam lines will be conducted sequentially to increase the operation efficiency by using it. To provide flexibility of the irradiation conditions, each beam line is designed to have specific beam parameters. The development of beamline components, including magnets, is conducted in parallel. The details will be reported.

  6. Status of Design of PEFP Beam Lines

    International Nuclear Information System (INIS)

    PEFP(Proton Engineering Frontier Project) is developing a high current 100MeV proton linear accelerator. 20MeV and 100MeV proton beam lines are also under development for beam applications. 10 beam lines will be developed to support various purposes. Two kind of proton beam energy will be transported to 2 beamlines for industrial applications and 3 beamlines for various researches. The characteristic design scheme of PEFP beam lines is the application of a programmable AC magnet. Beam distribution to 3 research beam lines will be conducted sequentially to increase the operation efficiency by using it. To provide flexibility of the irradiation conditions, each beam line is designed to have specific beam parameters. The development of beamline components, including magnets, is conducted in parallel. The details will be reported

  7. Radiation shielding of the beam absorber in the MI 8-GeV beam line

    Energy Technology Data Exchange (ETDEWEB)

    Rakhno, I.; /Fermilab

    2006-01-01

    Results of Monte Carlo radiation shielding calculations performed for the beam absorber of the MI 8 GeV beam line are presented and discussed. The possibility to reach the level of 10{sup 19} protons per year is investigated.

  8. Particle Beam Therapy for Cancer of the Skull Base, Nasal Cavity, and Paranasal Sinus

    OpenAIRE

    Fukumitsu, Nobuyoshi

    2012-01-01

    Particle beam therapy has been rapidly developed in these several decades. Proton and carbon ion beams are most frequently used in particle beam therapy. Proton and carbon ion beam radiotherapy have physical and biological advantage to the conventional photon radiotherapy. Cancers of the skull base, nasal cavity, and paranasal sinus are rare; however these diseases can receive the benefits of particle beam radiotherapy. This paper describes the clinical review of the cancer of the skull base,...

  9. Theoretical and Experimental Beam Plasma Physics (TEBPP)

    Science.gov (United States)

    Roberts, B.

    1986-01-01

    The theoretical and experimental beam plasma physics (TEBPP) consists of a package of five instruments to measure electric and magnetic fields, plasma density and temperature, neutral density, photometric emissions, and energetic particle spectra during firings of the particle injector (SEPAC) electron beam. The package is developed on a maneuverable boom (or RMS) and is used to measure beam characteristics and induced perturbations field ( 10 m) and mid field ( 10 m to 100 m) along the electron beam. The TEBPP package will be designed to investigate induced oscillations and induced electromagnetic mode waves, neutral and ion density and temperature effects, and beam characteristics as a function of axial distance.

  10. Crossed-Wire Laser Microwelding of Pt-10 Pct Ir to 316 Low-Carbon Vacuum Melted Stainless Steel: Part I. Mechanism of Joint Formation

    Science.gov (United States)

    Zou, G. S.; Huang, Y. D.; Pequegnat, A.; Li, X. G.; Khan, M. I.; Zhou, Y.

    2012-04-01

    The excellent biocompatibility and corrosion properties of Pt alloys and 316 low-carbon vacuum melted (LVM) stainless steel (SS) make them attractive for biomedical applications. With the increasing complexity of medical devices and in order to lower costs, the challenge of joining dissimilar materials arises. In this study, laser microwelding (LMW) of crossed Pt-10 pct Ir to 316 LVM SS wires was performed and the weldability of these materials was determined. The joint geometry, joining mechanism, joint breaking force (JBF), and fracture modes were investigated using optical microscopy, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and microtensile testing. It was shown that the mechanisms of joint formation transitioned from (1) brazing, (2) a combination of brazing and fusion welding, and (3) fusion welding with increasing pulsed laser energy. The joints demonstrated various tensile failure modes including (1) interfacial failure below a peak power of 0.24 kW, (2) partial interfacial failure that propagated into the Pt-Ir wire, (3) failure in the Pt-Ir wire, and (4) failure in the SS wire due to porosity and severe undercutting caused by overwelding. During this study, the optimal laser peak power range was identified to produce joints with good joint geometry and 90 pct of the tensile strength of the Pt-10 pct Ir wire.

  11. Measurement of the electroweak charge asymmetry of the cross section of the deep inelastic scattering of muons on carbon at 200 GeV beam momentum

    International Nuclear Information System (INIS)

    In the experiment described here the weak neutral current was detected for the first time in the inclusive deep inelastic muon-nucleon scattering μsup(+-)+N->μsup(+-)+X. In this reaction the γ-Z0 interference effects an asymmetry of the cross section at simultaneous change of charge and polarization of the muon beam. In the model of Glashow, Salam, and Weinberg this asymmetry is calculable and is in the kinematical range of this measurement in the order of magnitude of 1%. The results are in full agreement with the prediction and confirm for the first time the electron-muon universality of the coupling to the weak neutral current. According to the scales of high energy physics the measurement of a so small effect represents a precision experiment. A careful control of the systematic errors lies therefore in the center of the study. Beyond this thesis contains contributions which are also of importance for the analysis of other measurements with the same apparatus. (orig./HSI)

  12. Additional heat treatment of non-porous coatings obtained on medium carbon steel substrates by electron beam cladding of a Ti-Mo-C powder composition

    Science.gov (United States)

    Mul, D. O.; Drobyaz, E. A.; Zimoglyadova, T. A.; Bataev, V. A.; Lazurenko, D. V.; Shevtsova, L. I.

    2016-04-01

    The structure and microhardness of surface layers, obtained by non-vacuum electron beam cladding of Ti-Mo-C powder mixture on a steel substrate after different types of heat treatment, were investigated. After cladding samples were heat treated in a furnace at 200...500 °C, as well as quenched at 860 ° C and then underwent high-temperature tempering. Heat treatment of cladded coatings induced tempering of martensite and precipitation of cementite particles (Fe3C). Transmission electron microscopy of the samples after heating and holding at 300 ° C revealed precipitation of nanosized cubical TiC particles. The formation of hard nanosized particles led to the surface layer microhardness growth. The highest level of microhardness (which was 1.2...1.5-fold higher in comparison with coating microhardness after heat treatment) was achieved after heating of the claded material at 300 °C and 400 °C Additional quenching of samples at 860 °C did not increase the microhardness level.

  13. One-nucleon transfer reactions induced by secondary beam of {sup 11}Be: study of the nuclear structure of the exotic nuclei {sup 11}Be and {sup 10}Li; Reactions de transfert d'un nucleon induites par un faisceau secondaire de {sup 11}Be: etude de la structure des noyaux exotiques {sup 11}Be et {sup 10}Li

    Energy Technology Data Exchange (ETDEWEB)

    Pita, S

    2000-09-01

    The structure of the neutron rich light nuclei {sup 11}Be and {sup 10}Li has been investigated by means of one nucleon transfer reactions. The experiments have been carried out at GANIL in inverse kinematics using {sup 11}Be secondary beams. The {sup 11}Be(p,d){sup 10}Be reaction bas been studied at 35.3 MeV/u. The {sup 10}Be ejectiles were analyzed by the spectrometer SPEG, and coincident deuterons were detected in the position sensitive silicon detector CHARISSA. Transfer cross sections to 0{sup +}{sub 1} and 2{sup +}{sub 1}, states in {sup 10}Be were measured up to {theta}{sub CM} = 16 deg. and compared to DWBA and CRC predictions. The effects of neutron-cure couplings on reaction form factors have been studied by solving coupled equations in the framework of a vibrational model. It is shown that the rate of core excitation {sup 10}Be{sub 2+} in the {sup 11}Be{sub gs} wave function is overestimated by a standard analysis with form factors given by the usual Separation Energy prescription. The former model predicts a rate of core excitation of 16% and leads to theoretical cross sections which are in good agreement with the experimental data. The aim of the {sup 11}Be(d,{sup 3}He){sup 10}Li experiment, realized at 37 MeV/u, was to measure the distribution of the 2s neutron strength in the unbound nucleus {sup 10}Li. The energy spectrum was deduced from the {sup 3}He energy and angle measured by the silicon strip detector array MUST. An asymmetric peak is clearly observed near the threshold, with a maximum at -S{sub n} = 130 keV. This constitutes a direct proof of the inversion of 2s and 1p{sub 1/2} shells in {sup 10}Li, which was until now a controversial question in spite of many experimental efforts. On the other band the analysis of the {sup 11}Be(d,t){sup 10}Be reaction studied in the same experiment confirms the results obtained in the {sup 11}Be(p,d){sup 10}Be reaction concerning the {sup 11}Be{sub gs} structure. This work shows the interest and feasibility

  14. Beam Interlocks for LHC and SPS

    CERN Document Server

    Dinius, A; Gimeno-Vicente, J; Nouchi, P; Puccio, B; Schmidt, R; Wenninger, J

    2003-01-01

    The Large Hadron Collider at CERN (LHC) will operate at 7 TeV/c with a luminosity of 10 cms. This requires two beams with about 3^10 protons/beam, corresponding to a stored energy of about 350 MJ, sufficient to heat and melt 500 kg of copper. Protection of equipment from damage in case of uncontrolled beam losses is challenging. Injection of the beam from the SPS to the LHC could already damage equipment and is only permitted when all LHC systems are correctly prepared. In case of an uncontrolled loss of the circulating LHC beams, it is required to extract the beams into a specially designed target as soon as possible. Beam loss monitors and equipment for hardware surveillance are distributed around the 26 km long accelerator. In case of failures or beam losses, the beam interlock system is informed and sends a dump request to the beam dumping system. The beam interlock system also inhibits injection when the LHC is not ready for beam. In this paper the requirements for the beam interlock system are discussed...

  15. 预应力碳纤维片材在结构加固中的应用研究——以其对钢筋混凝土梁力学性能的增强为例%A Study on the Application of Prestressed Carbon Fiber Sheet Structure Reinforcement: Take the Reinforcement of Mechanical Performance of Reinforced Concrete Beams by it for Example

    Institute of Scientific and Technical Information of China (English)

    何令

    2012-01-01

    文章通过大型商业有限元软件ANSYS/Civil对预应力碳纤维片材增强钢筋混凝土梁的抗弯性能进行了数值模拟,分析了普通RC梁、碳纤维布增强RC梁、预应力碳纤维布增强RC梁的抗弯承载力、受力钢筋应力历程、RC梁挠度历程等力学性能.结果表明,粘贴预应力碳纤维布能够更好的改善钢筋混凝土梁的受力,提高增强RC梁的承载能力.%This article presents the carrying-out of the numerical simulation of the enhanced flexural performance of the concrete beams prestressed carbon fiber sheet of large commercial finite dement software ANSYS/Civil. It analyzes the mechanics properties of ordinary RC beam, carbon fiber enhanced RE beam, the bending proof carrying capacity of prestressed carbon fiber enhanced RC beam, the stress course of reinforced steel, the deflection proof course of RC beam. The finding reveals that bonding prestressed carbon fiber sheet is more capable to relax the stress on the steel concrete and enhance the stress of RC beams.

  16. Anomalous enhancement of drilling rate in carbon fiber reinforced plastic using azimuthally polarized CO2 laser

    Science.gov (United States)

    Endo, Masamori; Araya, Naohiro; Kurokawa, Yuki; Uno, Kazuyuki

    2016-09-01

    We developed an azimuthally polarized pulse-periodic CO2 laser for high-performance drilling applications. We discovered an anomalous enhancement in the drilling rate with the azimuthally polarized beam compared to that with radially or randomly polarized beams. We drilled 0.45 mm-thick carbon fiber reinforced plastic (CFRP) using a focusing lens with a focal length of 50 mm and a numerical aperture (NA) of 0.09. The conditions other than polarization states were identical for all the experiments. The azimuthally polarized beam exhibited a drilling rate more than 10 times greater on average than those of the other two polarizations.

  17. External Beam Therapy (EBT)

    Science.gov (United States)

    ... Physician Resources Professions Site Index A-Z External Beam Therapy (EBT) External beam therapy (EBT) is a ... follow-up should I expect? What is external beam therapy and how is it used? External beam ...

  18. New electron beam facility for irradiated plasma facing materials testing in hot cell

    Energy Technology Data Exchange (ETDEWEB)

    Sakamoto, N.; Kawamura, H. [Oarai Research Establishment, Ibaraki-ken (Japan); Akiba, M. [Naka Research Establishment, Ibaraki-ken (Japan)

    1995-09-01

    Since plasma facing components such as the first wall and the divertor for the next step fusion reactors are exposed to high heat loads and high energy neutron flux generated by the plasma, it is urgent to develop of plasma facing components which can resist these. Then, we have established electron beam heat facility ({open_quotes}OHBIS{close_quotes}, Oarai Hot-cell electron Beam Irradiating System) at a hot cell in JMTR (Japan Materials Testing Reactor) hot laboratory in order to estimate thermal shock resistivity of plasma facing materials and heat removal capabilities of divertor elements under steady state heating. In this facility, irradiated plasma facing materials (beryllium, carbon based materials and so on) and divertor elements can be treated. This facility consists of an electron beam unit with the maximum beam power of 50kW and the vacuum vessel. The acceleration voltage and the maximum beam current are 30kV (constant) and 1.7A, respectively. The loading time of electron beam is more than 0.1ms. The shape of vacuum vessel is cylindrical, and the mainly dimensions are 500mm in inner diameter, 1000mm in height. The ultimate vacuum of this vessel is 1 x 10{sup -4}Pa. At present, the facility for thermal shock test has been established in a hot cell. And performance estimation on the electron beam is being conducted. Presently, the devices for heat loading tests under steady state will be added to this facility.

  19. Polarized and depolarized Raman spectra of liquid carbon disulfide in the pressure range 0-10 kbar. I. Vibration frequencies, C-S bond length, and Fermi resonance

    Science.gov (United States)

    Ikawa, S.; Whalley, Edward

    1986-09-01

    The effect of pressure on the polarized and depolarized Raman spectra of liquid carbon disulphide, i.e., the peak frequencies, bandwidths, and relative intensities of both the allowed ν1 and 2ν2 bands and the interaction-induced ν2 and ν3 bands, have been measured at 22 °C up to 10 kbar. This paper discusses the effect of pressure on the frequencies and on the relative isotropic intensity of the ν1 and 2ν2 bands. The frequency of the ν1 band increases linearly with pressure, within the experimental uncertainty, at the rate 0.16±0.01 cm-1 kbar-1, and the frequencies of the ν2, ν3, and 2ν2 bands decrease nonlinearly. The frequency shifts are described by second-order perturbation theory with the molecular anharmonicity and the intermolecular interaction as perturbations. The leading terms of the shifts consist of the same derivative of the interaction potential, multiplied by different anharmonicity constants, and the shifts of the ν1 and 2ν2 bands suggests that the C-S bond length decreases at the rate 2×10-4 Å kbar-1. The relative isotropic intensity of the 2ν2 and ν1 bands increases with pressure at the rate 0.050 kbar-1, whereas the anisotropic 2ν2 intensity relative to the isotropic ν1 intensity is independent of pressure to the experimental precision of ˜0.005. The effect of pressure on the second derivative of the isotropic and anisotropic parts of the polarizability with respect to the bend coordinate was estimated as 1.1×10-43 C m2 V-1 kbar-1 and ˜0, respectively, from these values.

  20. Accuracy of a rapid 10-minute carbon-14 urea breath test for the diagnosis of Helicobacter pylori-associated peptic ulcer disease

    International Nuclear Information System (INIS)

    Urease in the human gastric mucosa is a marker for infection with Helicobacter pylori (HP), an organism which is associated with peptic ulcer disease. To detect gastric urease, we examined 184 patients (144 males, 40 females; mean age: 49.8±15.6 years) with suspected peptic ulcer disease. Fasting patients were given orally 5 μCi of carbon-14 labelled urea. For each patient only one breath sample was collected in hyamine at 10 min. The amount of 14C collected at 10 min was expressed as follows: [(DPM/mmol CO2 collected)/(DPM administered)]x100xbody weight (kg). The presence of HP colonization was determined by examination of multiple endoscopic prepyloric antral biopsy specimens subjected to culture or a rapid urease test. For the purpose of this study, HP-positive patients were defined as those with characteristic bacteria as indicated by a positive result of either the culture or the rapid urease test; HP-negative patients were defined as those with negative findings on both the culture and the rapid urease test. Of the 184 cases, 99 (53.8%) were positive for HP infection, and 85 (46.2%), negative. The sensitivity and specificity of the rapid 10 min 14C-urea breath test for the diagnosis of HP-associated peptic ulcer disease were evaluated by a receiver operating characteristic (ROC) curve with a variable cut-off value from 1.5 to 4.5. When a cut-off value of 1.5 was selected, the sensitivity was 100% and the specificity, 83.5%; when a cut-off value of 4.5 was selected, the sensitivity was 54.5% and the specificity, 97.6%. (orig.)