WorldWideScience

Sample records for capsule parametric design

  1. Optimal Design of Capsule Transporting Pipeline carrying Spherical Capsules

    Science.gov (United States)

    Asim, Taimoor; Mishra, Rakesh; Ubbi, Kuldip

    2012-05-01

    A capsule pipeline transports material or cargo in capsules propelled by fluid flowing through a pipeline. The cargo may either be contained in capsules (such as wheat enclosed inside sealed cylindrical containers), or may itself be the capsules (such as coal compressed into the shape of a cylinder or sphere). As the concept of capsule transportation is relatively new, the capsule pipelines need to be designed optimally for commercial viability. An optimal design of such a pipeline would have minimum pressure drop due to the presence of the solid medium in the pipeline, which corresponds to minimum head loss and hence minimum pumping power required to drive the capsules and the transporting fluid. The total cost for the manufacturing and maintenance of such pipelines is yet another important variable that needs to be considered for the widespread commercial acceptance of capsule transporting pipelines. To address this, the optimisation technique presented here is based on the least-cost principle. Pressure drop relationships have been incorporated to calculate the pumping requirements for the system. The maintenance and manufacturing costs have been computed separately to analyse their effects on the optimisation process. A design example has been included to show the usage of the model presented. The results indicate that for a specific throughput, there exists an optimum diameter of the pipeline for which the total cost for the piping system is at its minimum.

  2. Parametric Optimization of Hospital Design

    DEFF Research Database (Denmark)

    Holst, Malene Kirstine; Kirkegaard, Poul Henning; Christoffersen, L.D.

    2013-01-01

    Present paper presents a parametric performancebased design model for optimizing hospital design. The design model operates with geometric input parameters defining the functional requirements of the hospital and input parameters in terms of performance objectives defining the design requirements...... and preferences of the hospital with respect to performances. The design model takes point of departure in the hospital functionalities as a set of defined parameters and rules describing the design requirements and preferences....

  3. Parametric Fires for Structural Design

    DEFF Research Database (Denmark)

    Hertz, Kristian

    2012-01-01

    The authorities, the construction association, and a number of companies in Denmark have supported the author writing a guide for design of building structures for parametric fires. The guide is published by the ministry as a supplement to the building regulations. However, consultants and contra......The authorities, the construction association, and a number of companies in Denmark have supported the author writing a guide for design of building structures for parametric fires. The guide is published by the ministry as a supplement to the building regulations. However, consultants...... and contractors have asked for a reference in English in order to make the guide-lines and the background for them available internationally. The paper therefore presents recommendations from the design guide especially concerning how to assess parametric design fires based on the opening factor method for large...

  4. Parametric Thinking in Urban Design

    DEFF Research Database (Denmark)

    Steinø, Nicolai

    2010-01-01

    The paper states that most applications of parametric mod- elling to architecture and urban design fall into one of two strands of either form for form’s sake, or the negotiation of environmental con- cerns, while approaches which allow scenarios to be easily tested and modified without the appli...... of the paper. The pros and cons of this simple approach is discussed, and the paper con- cludes, that while it does not represent a suitable solution in all cases, it fills a gap among the existing approaches to parametric urban de- sign.......The paper states that most applications of parametric mod- elling to architecture and urban design fall into one of two strands of either form for form’s sake, or the negotiation of environmental con- cerns, while approaches which allow scenarios to be easily tested and modified without...

  5. Parametrics in Urban Design

    DEFF Research Database (Denmark)

    Steinø, Nicolai; Obeling, Esben

    2013-01-01

    The design of urban space has always been contested. Whether imposed by autocratic rulers, emerged as a result of market forces, or implemented as a result of democratic planning processes, urban space design shapes the lives of urban dwellers. Yet rarely does the average urban dweller have any r...... implementation by means of CityEngine is given and discussed with respect to it pros and cons. And finally, the potential implications of this approach are touched as an outline for further research....

  6. A parametric study on ice formation inside a spherical capsule

    Energy Technology Data Exchange (ETDEWEB)

    Ismail, K.A.R.; Silva, T.M. da [Depto. de Engenharia Termica e de Fluidos - FEM-UNICAMP CP: 6122, CEP 13083-970, SP, Campinas (Brazil); Henriquez, J.R. [Depto. de Engenharia Mecanica - DEMEC, UFPE, CEP 50740-530, PE, Recife (Brazil)

    2003-09-01

    This paper reports the results of a numerical study on the heat transfer during the process of solidification of water inside a spherical capsule. The governing equations of the problem and associated boundary conditions were formulated and solved using a finite difference approach and a moving grid scheme. The model was optimized and the numerical predictions were validated by comparison with experimental results realized by the authors. The model was also used to investigate the effects of the size and material of the shell, initial temperature of the phase change material and the external temperature of the spherical capsule on the solidified mass fraction and the time for the complete solidification. (authors)

  7. Systematic Design of edical Capsule Robots

    OpenAIRE

    Beccani, M; Tunc, H; Taddese, AZ; Susilo, E; Volgiesi, P; Ledeczi, A; Valdastri, P

    2015-01-01

    Medical capsule robots that navigate inside the body as diagnostic and interventional tools are an emerging and challenging research area within medical CPSs. These robots must provide locomotion, sensing, actuation, and communication within severe size, power, and computational constraints. This paper presents the first effort for an open architecture, platform design, software infrastructure, and a supporting modular design environment for medical capsule robots to further this research area.

  8. Design of parametric software tools

    DEFF Research Database (Denmark)

    Sabra, Jakob Borrits; Mullins, Michael

    2011-01-01

    the operations and functions of the design method. To evaluate the prototype potentials, surveys with architectural and healthcare design companies are conducted. Evaluation is done by the administration of questionnaires being part of the development of the tools. The results show that architects, designers......The studies investigate the field of evidence-based design used in architectural design practice and propose a method using 2D/3D CAD applications to: 1) enhance integration of evidence-based design knowledge in architectural design phases with a focus on lighting and interior design and 2) assess...... fulfilment of evidence-based design criterion regarding light distribution and location in relation to patient safety in architectural health care design proposals. The study uses 2D/3D CAD modelling software Rhinoceros 3D with plug-in Grasshopper to create parametric tool prototypes to exemplify...

  9. Parametric Design Strategies for Collaborative Urban Design

    DEFF Research Database (Denmark)

    Steinø, Nicolai; Yıldırım, Miray Baş; Özkar, Mine

    2013-01-01

    to the collaboration between professionals, participation by different non-professional stakeholders, such as residents, local authorities, non-governmental organizations and investors, is another important component of collaborative urban design processes. The involvement of community in decision making process...... urban space, subject to urban renewal. A key aspect of the workshop therefore, was to develop different design scenarios and to use parametric design software to communicate the scenarios spatially, as well as to mediate between them. Parametric urban design is a potentially powerful tool...... is working alone with distributed design problem packages which means decomposition of design problems into tasks and working on them individually. On the other hand, collaborative design is based on communication. Participants work together on design problems in an integrated design process. In addition...

  10. Development of capsule design support subprograms for 3-dimensional temperature calculation using FEM Code NISA

    Energy Technology Data Exchange (ETDEWEB)

    Tobita, Masahiro; Matsui, Yoshinori [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment

    2003-03-01

    Prediction of irradiation temperature is one of the important issues in the design of the capsule for irradiation test. Many kinds of capsules with complex structure have been designed for recent irradiation requests, and three-dimensional (3D) temperature calculation becomes inevitable for the evaluation of irradiation temperature. For such 3D calculation, however, many works are usually needed for input data preparation, and a lot of time and resources are necessary for parametric studies in the design. To improve such situation, JAERI introduced 3D-FEM (finite element method) code NISA (Numerically Integrated elements for System Analysis) and developed several subprograms, which enabled to support input preparation works in the capsule design. The 3D temperature calculation of the capsule are able to carried out in much easier way by the help of the subprograms, and specific features in the irradiation tests such as non-uniform gamma heating in the capsule, becomes to be considered. (author)

  11. Developing a Parametric Urban Design Tool

    DEFF Research Database (Denmark)

    Steinø, Nicolai; Obeling, Esben

    2014-01-01

    Parametric urban design is a potentially powerful tool for collaborative urban design processes. Rather than making one- off designs which need to be redesigned from the ground up in case of changes, parametric design tools make it possible keep the design open while at the same time allowing...

  12. Design of Endoscopic Capsule With Multiple Cameras.

    Science.gov (United States)

    Gu, Yingke; Xie, Xiang; Li, Guolin; Sun, Tianjia; Wang, Dan; Yin, Zheng; Zhang, Pengfei; Wang, Zhihua

    2015-08-01

    In order to reduce the miss rate of the wireless capsule endoscopy, in this paper, we propose a new system of the endoscopic capsule with multiple cameras. A master-slave architecture, including an efficient bus architecture and a four level clock management architecture, is applied for the Multiple Cameras Endoscopic Capsule (MCEC). For covering more area of the gastrointestinal tract wall with low power, multiple cameras with a smart image capture strategy, including movement sensitive control and camera selection, are used in the MCEC. To reduce the data transfer bandwidth and power consumption to prolong the MCEC's working life, a low complexity image compressor with PSNR 40.7 dB and compression rate 86% is implemented. A chipset is designed and implemented for the MCEC and a six cameras endoscopic capsule prototype is implemented by using the chipset. With the smart image capture strategy, the coverage rate of the MCEC prototype can achieve 98% and its power consumption is only about 7.1 mW.

  13. Programmatic Formation: Practical Applications of Parametric Design

    OpenAIRE

    Madkour, Yehia; Erhan, Halil; Neumann, Oliver

    2009-01-01

    Programmatic Formation explores design as a responsive process.The study we present engages the complexity of the surroundings using parametric and generative design methods. It illustrates that responsiveness of designs can be achieved beyond geometric explorations.The parametric models can combine and respond simultaneously to design and its programmatic factors, such as performance-sensitive design-decisions, and constraints.We demonstrate this through a series of case st...

  14. Parametric Design of Modular Fixture Structure

    Institute of Scientific and Technical Information of China (English)

    陈冰冰

    2001-01-01

    Based on an example of its typical structure, the concept of modular fixture structure module is presented, and the structure module system of modular fixture is summarized. Then the parametric design of structure is discussed, and its advantages are also emphasized.Furthermore, some specific methods are provided, such as the selection of fixture components, the determination and input of parameters, drawing representative model,and the creation of drawing. Finally an applied example of strcture parametric design is presented.

  15. Parametric Architectural Design with Point-clouds

    DEFF Research Database (Denmark)

    Zwierzycki, Mateusz; Evers, Henrik Leander; Tamke, Martin

    2016-01-01

    This paper investigates the efforts and benefits of the implementation of point clouds into architectural design processes and tools. Based on a study on the principal work processes of designers with point clouds the prototypical plugin/library - Volvox - was developed for the parametric modelli...

  16. Using Parametrics to Facilitate Collaborative Urban Design

    DEFF Research Database (Denmark)

    Steinø, Nicolai; Benbih, Karima; Obeling, Esben

    2013-01-01

    Collaborative urban design faces three inherent dilemmas of limitations to time and resources, of barriers to language and communication between professionals and stakeholders, and of the reciprocal nature of the relation between influence and understanding. Parametric design tools may address all...... of these dilemmas, as they provide a fast way to test different design scenarios and make it possible keep designs open while at the same time allowing for a level of detailing which is high enough to facilitate an understanding of the generic qualities of proposed designs. This is particularly relevant...... in the context of the urban South which is characterized by high urban growth rates, weak planning systems and modest means. The current state of planning and urban development in Morocco is introduced as a context for discussing collaborative urban design and parametric urban design, and some tentative...

  17. Interdisciplinary parametric design: the XXL experience

    NARCIS (Netherlands)

    Turrin, M.; Sariyildiz, I.S.; Paul, J.C.

    2015-01-01

    Focusing on large span structures for sport buildings, the paper tackles the role of parametric modelling and performance simulations, to enhance the integration between architectural and engineering design. The general approach contrasts post-engineering processes. In post-engineering, technical pe

  18. PARAMETRIC DESIGN OF DELTA ROBOT

    Directory of Open Access Journals (Sweden)

    Mert Gürgen

    2016-09-01

    Full Text Available This article describes a sophisticated determination and presentation of a workspace volume for a delta robot, with consideration of its kinematic behavior. With the help of theoretical equations, optimization is performed with the aid of the stiffness and dexterity analysis. Theoretical substructure is coded in Matlab and three-dimensional (3D data for delta robot are developed in computer-aided design (CAD environment. In later stages of the project, both 3D and theoretical data are linked together and thus, with the changing design parameter of the robot itself, the Solidworks CAD output adapts and regenerates output with a new set of parameters. To achieve an optimum workspace volume with predefined parameters, a different set of robot parameters are iterated through design optimization in Matlab, and the delta robot design is finalized and illustrated in the 3D CAD environment, Solidworks. This study provides a technical solution to accomplish a generic delta robot with optimized workspace volume.

  19. Parametric Thinking in Urban Design

    DEFF Research Database (Denmark)

    Steinø, Nicolai

    2010-01-01

    the application of complex and expensive technolo- gies are mostly absent, although they seem appropriate in urban de- sign. A survey of existing approaches confirms the statement, and an example of the application of basic knowledge of geometry and para- metric thinking to urban design forms the argument...

  20. A computer application for parametric aircraft design

    Science.gov (United States)

    Fraqueiro, Filipe R.; Albuquerque, Pedro F.; Gamboa, Pedro V.

    2016-11-01

    The present work describes the development and final result of a graphical user interface tailored for a mission-based parametric aircraft design optimization code which targets the preliminary design phase of unmanned aerial vehicles. This development was built from the XFLR5 open source platform and further benefits from two-dimensional aerodynamic data obtained from XFOIL. For a better understanding, the most important graphical windows are shown. In order to demonstrate the graphical user interface interaction with the aircraft designer, the results of a case study which maximizes payload are presented.

  1. Mems Q-Factor Enhancement Using Parametric Amplification: Theoretical Study and Design of a Parametric Device

    CERN Document Server

    Grasser, L; Parrain, F; Roux, X Le; Gilles, J -P

    2008-01-01

    Parametric amplification is an interesting way of artificially increasing a MEMS Quality factor and could be helpful in many kinds of applications. This paper presents a theoretical study of this principle, based on Matlab/Simulink simulations, and proposes design guidelines for parametric structures. A new device designed with this approach is presented together with the corresponding FEM simulation results.

  2. Plastic ablator ignition capsule design for the National Ignition Facility

    Energy Technology Data Exchange (ETDEWEB)

    Clark, D S; Haan, S W; Hammel, B A; Salmonson, J D; Callahan, D A; Town, R P

    2009-12-01

    The National Ignition Campaign, tasked with designing and fielding targets for fusion ignition experiments on the National Ignition Facility (NIF), has carried forward three complementary target designs for the past several years: a beryllium ablator design, a plastic ablator design, and a high-density carbon or synthetic diamond design. This paper describes current simulations and design optimization to develop the plastic ablator capsule design as a candidate for the first ignition attempt on NIF. The trade-offs in capsule scale and laser energy that must be made to achieve a comparable ignition probability to that with beryllium are emphasized. Large numbers of 1-D simulations, meant to assess the statistical behavior of the target design, as well as 2-D simulations to assess the target's susceptibility to Rayleigh-Taylor growth are presented.

  3. Thermohydraulic design of saturated temperature capsule for IASCC irradiation test

    Energy Technology Data Exchange (ETDEWEB)

    Ide, Hiroshi; Matsui, Yoshinori; Itabashi, Yukio [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment] [and others

    2002-10-01

    An advanced water chemistry controlled irradiation research device is being developed in JAERI, to perform irradiation tests for irradiation assisted stress corrosion cracking (IASCC) research concerned with aging of LWR. This device enables the irradiation tests under the water chemistry condition and the temperature, which simulate the conditions for BWR core internals. The advanced water chemistry controlled irradiation research device is composed of saturated temperature capsule inserted into the JMTR core and the water chemistry control unit installed in the reactor building. Regarding the saturated temperature capsule, the Thermohydraulic design of capsule structure was done, aimed at controlling the specimen's temperature, feeding water velocity on specimen's surface to the environment of BWR nearer. As the result of adopting the new capsule structure based on the design study, it was found out that feeding water velocity at the surface of specimen's is increased to about 10 times as much as before, and nuclear heat generated in the capsule components can be removed safely even in the abnormal event such as the case of loss of feeding water. (author)

  4. Parametric control systems design with applications in missile control

    Institute of Scientific and Technical Information of China (English)

    DUAN GuangRen; YU HaiHua; TAN Feng

    2009-01-01

    This paper considers parametric control of high-order descriptor linear systems via proportional plus derivative feedback.By employing general parametric solutions to a type of so-called high-order Sylvester matrix equations,complete parametric control approaches for high-order linear systems are presented.The proposed approaches give simple complete parametric expressions for the feedback gains and the closed-loop eigenvector matrices,and produce all the design degrees of freedom.Furthermore,Important special cases are particularly treated.Based on the proposed parametric design approaches,a parametric method for the gain-scheduling controller design of a linear time-varying system is proposed and the design of a BTT missile autopilot is carried out.The simulation results show that the method is superior to the traditional one in sense of either global stability or system performance.

  5. Parametric Collaborative Design of Network-based Mechanical Products

    Institute of Scientific and Technical Information of China (English)

    WU Shu-fang; YU Guo-jun; WANG Zong-yan; SU Tie-xiong; QIN Hui-bin

    2012-01-01

    Aiming at the problems of low-level information sharing, slow transmission and repetitive work in the designing process of product series, the internet-oriented parametric collaborative design method is proposed, in which the problems of sharing conflict and network heterogeneous in the distributed collaborative design are analyzed, and the construction method of collaborative design platforms based on PDMWorks Workgroup is put forward. Through studying the mechanism of roles distribution and function allocation and data concurrency control, the communication mechanism of internet-oriented collaborative design is formulated. On the basis of structure features of overhead travelling crane, through combining parametric variant design with collaborative design, internet-oriented parametric collaborative design system of overhead travelling crane is developed and verified through main girder design. In the paper, the internet-oriented parametric collaborative design method is proposed, aiming to solve the problems of low-level information sharing, slow transmission and repetitive work in the designing process of product series. The problems of sharing conflict and network heterogeneous in the distributed collaborative design are analyzed. The construction method of collaborative design platforms based on PDMWorks Workgroup is put forward. The communication mechanism of internet-oriented collaborative design is formulated, through studying the mechanism of roles distribution and function allocation and data concurrency control. On the basis of structure features of overhead travelling crane, through combining parametric variant design with collaborative design, internet-oriented parametric collaborative design system of overhead travelling crane is developed and verified through main girder design.

  6. A Parametric Urban Design Approach to Urban Development in Cairo

    DEFF Research Database (Denmark)

    Steinø, Nicolai

    2017-01-01

    -designer professionals can provide input and evaluate the spatial effects instantly in the context of participatory design processes. Cairo, Egypt, currently experiences rapid urban growth, while formal urban planning is absent in large parts, resulting in large-scale informal and unplanned development. A parametric...... in the course of participatory processes, as the consequences of changing different parameters cannot easily be evaluated by means of traditional design tools. In recent years, new parametric design tools have opened up new possibilities for dynamic scenario building in urban design. By way of a parametric...... design approach, different urban design parameters can be modified and new urban space scenarios can be rendered three-dimensionally in almost real time. In short, this is parametric urban design. It opens up completely new possibilities for participatory design, as both lay stakeholders and non...

  7. Design and synthesis of organic-inorganic hybrid capsules for biotechnological applications.

    Science.gov (United States)

    Shi, Jiafu; Jiang, Yanjun; Wang, Xiaoli; Wu, Hong; Yang, Dong; Pan, Fusheng; Su, Yanlei; Jiang, Zhongyi

    2014-08-07

    Organic-inorganic hybrid capsules, which typically possess a hollow lumen and a hybrid wall, have emerged as a novel and promising class of hybrid materials and have attracted enormous attention. In comparison to polymeric capsules or inorganic capsules, the hybrid capsules combine the intrinsic physical/chemical properties of the organic and inorganic moieties, acquire more degrees of freedom to manipulate multiple interactions, create hierarchical structures and integrate multiple functionalities. Thus, the hybrid capsules exhibit superior mechanical strength (vs. polymeric capsules) and diverse functionalities (vs. inorganic capsules), which may give new opportunities to produce high-performance materials. Much effort has been devoted to exploring innovative and effective methods for the synthesis of hybrid capsules that exhibit desirable performance in target applications. This tutorial review firstly presents a brief description of the capsular structure and hybrid materials in nature, then classifies the hybrid capsules into molecule-hybrid capsules and nano-hybrid capsules based upon the size of the organic and inorganic moieties in the capsule wall, followed by a detailed discussion of the design and synthesis of the hybrid capsules. For each kind of hybrid capsule, the state-of-the-art synthesis methods are described in detail and a critical comment is embedded. The applications of these hybrid capsules in biotechnological areas (biocatalysis, drug delivery, etc.) have also been summarized. Hopefully, this review will offer a perspective and guidelines for the future research and development of hybrid capsules.

  8. Design criteria for ultrafast optical parametric amplifiers

    Science.gov (United States)

    Manzoni, C.; Cerullo, G.

    2016-10-01

    Optical parametric amplifiers (OPAs) exploit second-order nonlinearity to transfer energy from a fixed frequency pump pulse to a variable frequency signal pulse, and represent an easy way of tuning over a broad range the frequency of an otherwise fixed femtosecond laser system. OPAs can also act as broadband amplifiers, transferring energy from a narrowband pump to a broadband signal and thus considerably shortening the duration of the pump pulse. Due to these unique properties, OPAs are nowadays ubiquitous in ultrafast laser laboratories, and are employed by many users, such as solid state physicists, atomic/molecular physicists, chemists and biologists, who are not experts in ultrafast optics. This tutorial paper aims at providing the non-specialist reader with a self-consistent guide to the physical foundations of OPAs, deriving the main equations describing their performance and discussing how they can be used to understand their most important working parameters (frequency tunability, bandwidth, pulse energy/repetition rate scalability, control over the carrier-envelope phase of the generated pulses). Based on this analysis, we derive practical design criteria for OPAs, showing how their performance depends on the type of the nonlinear interaction (crystal type, phase-matching configuration, crystal length), on the characteristics of the pump pulse (frequency, duration, energy, repetition rate) and on the OPA architecture.

  9. Parametric Design of Outdoor Broadcasting Studio Based on Schema Theory

    Directory of Open Access Journals (Sweden)

    Zhu Li

    2016-01-01

    Full Text Available This paper mainly demonstrates that the schema is an important way for the architect to cognize architecture form logic. It connects schema to algorithm of parametric design in order to seek the “algorithm schema” generation in parametric design of architecture. Meanwhile, this paper discusses the generative process and methods of the “algorithm schema” in parametric design of architecture by describing a case of outdoor broadcasting studio of Hunan Economic Radio. It also reveals the importance of “algorithm schema” for the cognition and architectural form logic generation.

  10. Variable Relation Parametric Model on Graphics Modelon for Collaboration Design

    Institute of Scientific and Technical Information of China (English)

    DONG Yu-de; ZHAO Han; LI Yan-feng

    2005-01-01

    A new approach to variable relation parametric model for collaboration design based on the graphic modelon has been put forward. The paper gives a parametric description model of graphic modelon, and relating method for different graphic modelon based on variable constraint. At the same time, with the aim of engineering application in the collaboration design, the autonmous constraint in modelon and relative constraint between two modelons are given. Finally, with the tool of variable and relation dbase, the solving method of variable relating and variable-driven among different graphic modelon in a part, and doubleacting variable relating parametric method among different parts for collaboration are given.

  11. A Generic Synthesis Algorithm for Well-Defined Parametric Design

    NARCIS (Netherlands)

    Schotborgh, W.O.; Kokkeler, F.G.M.; Tragter, H.; Bomhoff, M.J.; Houten, van F.J.A.M.

    2008-01-01

    This paper aims to improve the way synthesis tools can be built by formalizing: 1) the design artefact, 2) related knowledge and 3) an algorithm to generate solutions. This paper focuses on well-defined parametric engineering design, ranging from machine elements to industrial products. A design art

  12. Parametric toolpath design in metal spinning

    OpenAIRE

    Polyblank, James A.; Allwood, Julian M.

    2015-01-01

    This is the final version of the article. It first appeared from Elsevier via http://dx.doi.org/10.1016/j.cirp.2015.04.077 Toolpaths in metal spinning are still designed by human operators, largely by intuition: a scientific basis remains elusive. In this paper, a parameterised toolpath is proposed based on a quadratic Bezier curve. Experiments are performed varying each of four design parameters in turn, to investigate how tool force, part geometry and various failure modes evolve with ke...

  13. Biomimetic/Bioinspired Design of Enzyme@capsule Nano/Microsystems.

    Science.gov (United States)

    Shi, J; Jiang, Y; Zhang, S; Yang, D; Jiang, Z

    2016-01-01

    Enzyme@capsule nano/microsystems, which refer to the enzyme-immobilized capsules, have received tremendous interest owing to the combination of the high catalytic activities of encapsulated enzymes and the hierarchical structure of the capsule. The preparation of capsules and simultaneous encapsulation of enzymes is recognized as the core process for the rational design and construction of enzyme@capsule nano/microsystems. The strategy used has three major steps: (a) generation of the templates, (b) surface coating on the templates, and (c) removal of the templates, and it has been proven to be effective and versatile for the construction of enzyme@capsule nano/microsystems. Several conventional methods, including layer-by-layer assembly of polyelectrolytes, liquid crystalline templating method, etc., were used to design and construct enzyme@capsule nano/microsystems, but these have two major drawbacks. One is the low mechanical stability of the systems and the second is the harsh conditions used in the construction process. Learning from nature, several biomimetic/bioinspired methods such as biomineralization, biomimetic/bioinspired adhesion, and their combination have been exploited for the construction of enzyme@capsule nano/microsystems. In this chapter, we will present a general protocol for the construction of enzyme@capsule nano/microsystems using the latter approach. Some suggestions for improved design, construction, and characterization will also be presented with detailed procedures for specific examples.

  14. Rapid Airplane Parametric Input Design (RAPID)

    Science.gov (United States)

    Smith, Robert E.

    1995-01-01

    RAPID is a methodology and software system to define a class of airplane configurations and directly evaluate surface grids, volume grids, and grid sensitivity on and about the configurations. A distinguishing characteristic which separates RAPID from other airplane surface modellers is that the output grids and grid sensitivity are directly applicable in CFD analysis. A small set of design parameters and grid control parameters govern the process which is incorporated into interactive software for 'real time' visual analysis and into batch software for the application of optimization technology. The computed surface grids and volume grids are suitable for a wide range of Computational Fluid Dynamics (CFD) simulation. The general airplane configuration has wing, fuselage, horizontal tail, and vertical tail components. The double-delta wing and tail components are manifested by solving a fourth order partial differential equation (PDE) subject to Dirichlet and Neumann boundary conditions. The design parameters are incorporated into the boundary conditions and therefore govern the shapes of the surfaces. The PDE solution yields a smooth transition between boundaries. Surface grids suitable for CFD calculation are created by establishing an H-type topology about the configuration and incorporating grid spacing functions in the PDE equation for the lifting components and the fuselage definition equations. User specified grid parameters govern the location and degree of grid concentration. A two-block volume grid about a configuration is calculated using the Control Point Form (CPF) technique. The interactive software, which runs on Silicon Graphics IRIS workstations, allows design parameters to be continuously varied and the resulting surface grid to be observed in real time. The batch software computes both the surface and volume grids and also computes the sensitivity of the output grid with respect to the input design parameters by applying the precompiler tool

  15. PARAMETRIC OPTIMIZATION AND STRUCTURAL DESIGN OF NLS

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A physical and mathematical model is developed for describing nitrogen launching system (NLS)based on the dynamics of pneumatics and mechanisms. The multi-objective optimization function for the pitching angle and velocity of a missile was proposed for the first time. Singularity detection of wavelet analysis was conducted to find the optimum iteration points in a new direct algorithm of nonlinear programming. Comparison between wavelet optimization and complex method show that the former is better for optimization design.``

  16. Changing space and sound: Parametric design and variable acoustics

    Science.gov (United States)

    Norton, Christopher William

    This thesis examines the potential for parametric design software to create performance based design using acoustic metrics as the design criteria. A former soundstage at the University of Southern California used by the Thornton School of Music is used as a case study for a multiuse space for orchestral, percussion, master class and recital use. The criteria used for each programmatic use include reverberation time, bass ratio, and the early energy ratios of the clarity index and objective support. Using a panelized ceiling as a design element to vary the parameters of volume, panel orientation and type of absorptive material, the relationships between these parameters and the design criteria are explored. These relationships and subsequently derived equations are applied to Grasshopper parametric modeling software for Rhino 3D (a NURBS modeling software). Using the target reverberation time and bass ratio for each programmatic use as input for the parametric model, the genomic optimization function of Grasshopper - Galapagos - is run to identify the optimum ceiling geometry and material distribution.

  17. Parametric design study of ``power stick'' and its derivatives

    Science.gov (United States)

    Schock, Alfred; Or, Chuen T.

    1995-01-01

    The paper addresses some major concerns about the Power Stick concept proposed by Jet Propulsion Laboratory (JPL) personnel, and describes parametric studies of derivative designs to determine to what extent those concerns can be alleviated. The Power Stick and its derivatives are based on the use of the 1-watt(t) Radioisotope Heater Unit (RHU) to power a thermoelectric multicouple. Our study concludes that: (a) while the RHU has been safety-qualified as a low-temperature heater, additional reentry analyses and test would be needed to qualify it as a higher temperature heat source for the Power Stick, (b) even after parametric design optimization, the efficiency of the Power Stick and its derivatives is only 2.2%, and, (c) all generators based on the 1-watt heat source require a thermoelectric multicouple with a large number of extremely thin legs, of very doubtful fabricability.

  18. Introduction to the ANSYS Parametric Design Language (APDL)

    CERN Document Server

    Strain, Jeff; Miller, Eric

    2013-01-01

    The definitive guide to the ANSYS Parametric Design Language (APDL), the command language for the ANSYS Mechanical APDL product from ANSYS, Inc. PADT has converted their popular "Introduction to APDL" class into a guide so that users can teach themselves the APDL language at their own pace. Its 12 chapters include reference information, examples, tips and hints, and eight workshops. Topics covered include: - Parameters - User Interfacing - Program Flow - Retrieving Database Information - Arrays, Tables, and Strings - Importing Data - Writing Output to Files - Menu Customization

  19. Parametric Design Strategy Aiming at Environmentally Sustainable Residential Buildings

    DEFF Research Database (Denmark)

    Hansen, Hanne Tine Ring; Knudstrup, Mary-Ann; Heiselberg, Per

    2007-01-01

    This paper presents the preliminary conclusions from a PhD study about methodical approaches to environmentally sustainable architecture. The presented results are from a local sensitivity analysis focused on the energy consumption of a typical residential reference building, when it is subjected...... to a parametric study of the impact of changes in input parameters relating to the design and the use of the building....

  20. Design and manufacturing of 05F-01K instrumented capsule for nuclear fuel irradiation in Hanaro

    Energy Technology Data Exchange (ETDEWEB)

    Sohn, J. M.; Shin, Y. T.; Park, S. J. (and others)

    2007-07-15

    An instrumented capsule was developed to be able to measure fuel characteristics, such as fuel temperature, internal pressure of fuel rod, fuel pellet elongation, and neutron flux, etc., during the irradiation test of nuclear fuel in Hanaro. The instrumented capsule(02F-11K) for measuring and monitoring and monitoring fuel centerline temperature and neutron flux was designed and manufactured. It was successfully irradiated in the test hole OR5 of Hanaro from March 14, 2003 to June 1, 2003 (53.84 full power days at 24 MW). In the year of 2004, 3 test fuel rods and the instrumented capsule(03F-05K) were designed and manufactured to measure fuel centerline temperature, internal pressure of fuel rod, and fuel axial deformation during irradiation test. This capsule was irradiated in the test hole OR5 of Hanaro reactor from April 26, 2004 to October 1, 2004 (59.5 EFPD at 24 {approx} 30 MW). The six typed dual instrumented fuel rods, which allow for two characteristics to be measured simultaneously in one fuel rod, have been designed and manufactured to enhance the efficiency of the irradiation test using the instrumented fuel capsule. The 05F-01K instrumented fuel capsule was designed and manufactured for a design verification test of the three dual instrumented fuel rods. The irradiation test of the 05F-01K instrumented fuel capsule will be carried out at the OR5 vertical experimental hole of Hanaro.

  1. PARAMETRIC MODELING, CREATIVITY, AND DESIGN: TWO EXPERIENCES WITH ARCHITECTURE’ STUDENTS

    Directory of Open Access Journals (Sweden)

    Wilson Florio

    2012-02-01

    Full Text Available The aim of this article is to reflect on the use of the parametric modeling in two didactic experiences. The first experiment involved resources of the Paracloud program and its relation with the Rhinoceros program, that resulted in the production of physical models produced with the aid of the laser cutting. In the second experiment, the students had produced algorithms in the Grasshopper, resulting in families of structures and coverings. The study objects are both the physical models and digital algorithms resultants from this experimentation. For the analysis and synthesis of the results, we adopted four important assumptions: 1. the value of attitudes and environment of work; 2. the importance of experimentation and improvisation; 3. understanding of the design process as a situated act and as a ill-defined problem; 4. the inclusion of creative and critical thought in the disciplines. The results allow us to affirm that the parametric modeling stimulates creativity, therefore allowing combination of different parameters, that result in unexpected discoveries. Keywords: Teach-Learning, Parametric Modeling, Laser Cutter, Grasshopper, Design Process, Creativity.

  2. Design modification and stress analysis of bottom structure for the instrumented capsule

    Energy Technology Data Exchange (ETDEWEB)

    Choi, M. H.; Kang, Y. H.; Joo, K. N.; Oh, J. M.; Joe, M. S.; Ryu, J. S.; Jeo, Y. G. [KAERI, Taejon (Korea, Republic of)

    2003-10-01

    The bottom structure of the instrumented capsule, which is used for the irradiation test in the HANARO incore, plays an important role to support the capsule main structure within the hexagonal flow tube. This paper is described the design modification and stress analysis results to obtain the structural integrity of bottom structure for the instrumented capsule. The capsule's bottom guide structure consisted of three guide pins before, but it is modified as one block structure to obtain an efficient flow of coolant water and a stabilized shape structurally. The structural integrity of the bottom structure is estimated by the stress calculation of components such as welding parts, bolts and neck parts of the rod tip due to the force applied by handling tool. The tensile and shear stresses are calculated by using a mechanical formulas, and a finite element model development is planned to be performed for more complex assembly of the capsule bottom structure.

  3. Parametric design of tri-axial nested Helmholtz coils.

    Science.gov (United States)

    Abbott, Jake J

    2015-05-01

    This paper provides an optimal parametric design for tri-axial nested Helmholtz coils, which are used to generate a uniform magnetic field with controllable magnitude and direction. Circular and square coils, both with square cross section, are considered. Practical considerations such as wire selection, wire-wrapping efficiency, wire bending radius, choice of power supply, and inductance and time response are included. Using the equations provided, a designer can quickly create an optimal set of custom coils to generate a specified field magnitude in the uniform-field region while maintaining specified accessibility to the central workspace. An example case study is included.

  4. Parametric Approach in Designing Large-Scale Urban Architectural Objects

    Directory of Open Access Journals (Sweden)

    Arne Riekstiņš

    2011-04-01

    Full Text Available When all the disciplines of various science fields converge and develop, new approaches to contemporary architecture arise. The author looks towards approaching digital architecture from parametric viewpoint, revealing its generative capacity, originating from the fields of aeronautical, naval, automobile and product-design industries. The author also goes explicitly through his design cycle workflow for testing the latest methodologies in architectural design. The design process steps involved: extrapolating valuable statistical data about the site into three-dimensional diagrams, defining certain materiality of what is being produced, ways of presenting structural skin and structure simultaneously, contacting the object with the ground, interior program definition of the building with floors and possible spaces, logic of fabrication, CNC milling of the proto-type. The author’s developed tool that is reviewed in this article features enormous performative capacity and is applicable to various architectural design scales.Article in English

  5. Parametric modeling of DSC-MRI data with stochastic filtration and optimal input design versus non-parametric modeling.

    Science.gov (United States)

    Kalicka, Renata; Pietrenko-Dabrowska, Anna

    2007-03-01

    In the paper MRI measurements are used for assessment of brain tissue perfusion and other features and functions of the brain (cerebral blood flow - CBF, cerebral blood volume - CBV, mean transit time - MTT). Perfusion is an important indicator of tissue viability and functioning as in pathological tissue blood flow, vascular and tissue structure are altered with respect to normal tissue. MRI enables diagnosing diseases at an early stage of their course. The parametric and non-parametric approaches to the identification of MRI models are presented and compared. The non-parametric modeling adopts gamma variate functions. The parametric three-compartmental catenary model, based on the general kinetic model, is also proposed. The parameters of the models are estimated on the basis of experimental data. The goodness of fit of the gamma variate and the three-compartmental models to the data and the accuracy of the parameter estimates are compared. Kalman filtering, smoothing the measurements, was adopted to improve the estimate accuracy of the parametric model. Parametric modeling gives a better fit and better parameter estimates than non-parametric and allows an insight into the functioning of the system. To improve the accuracy optimal experiment design related to the input signal was performed.

  6. Introduction to the ANSYS Parametric Design Language (APDL)

    CERN Document Server

    Strain, Jeff

    2016-01-01

    The definitive guide to the ANSYS Parametric Design Language (APDL), the command language for the ANSYS Mechanical APDL product from ANSYS, Inc. PADT has converted their popular "Introduction to APDL" class into a guide so that users can teach themselves the APDL language at their own pace. Its 14 chapters include reference information, examples, tips and hints, and eight workshops. Topics covered include: - Parameters - User Interfacing - Program Flow - Retrieving Database Information - Arrays, Tables, and Strings - Importing Data - Writing Output to Files - Menu Customization - APDL Math - Using APDL in ANSYS Mechanical

  7. A Design Proposal for an Inexpensive Parametric Array

    Science.gov (United States)

    1991-01-01

    surface. An alternative parametric array design that has the advantage of electrical beam-steering is to use an array of small ( Tonpilz ) piston drivers...IN dB// 1,.BAR Dp - 0. 05 ’r -a. 55 r U, U, RANGE OF OUTER EDGE OF ,,50 rx THE LINE OF CERAMIC RANGE OF EDGE OF I TRANSDUCER REFLECTOR 0 0.5 1. 0... transducer scaling law indicates that the acoustic power increases as the square of the dimensional increase. Thus for rings with twice the size, we would have

  8. Parametric design of a part with free-form surfaces

    Institute of Scientific and Technical Information of China (English)

    KIM Yeoung-il; KIM Li-ra; JUN Cha-soo

    2006-01-01

    3D solid models for parts with regular-form surfaces (PRFSs) are effectively generated using traditional parametric design techniques. A new model is obtained by changing some parameters defining the model. The parts with free-form surfaces(PFFSs), however, cannot be defined by several parameters. Usually they are defined by some geometric elements like profile curves. The traditional parametric design approaches have not easily dealt with the PFFSs. A method for generating a solid model and an engineering drawing for PFFSs is proposed in this paper: First, the new profiles are generated from input point data. Second,the profile information is extracted from the existing model. Last, the old profiles are replaced with the new profiles. This method can preserve the associative information of the existing model and automatically generate the drawing including views, dimensions, and annotations. The proposed method has been implemented using a commercial CAD/CAM system, Unigraphics, and API functions written in C-language, and were applied to the blades of a turbine generator. Some illustrative examples are provided in order to show the effectiveness of the proposed method.

  9. Design of on-demand wireless capsule endoscope

    Institute of Scientific and Technical Information of China (English)

    Yang Li; Eric W Able; Peng Chenglin

    2008-01-01

    An on-demand wireless capsule endoscope with full-digital and bidirectional communication is presented,aiming at fulfilling the requirements of micromation and micropower consumption of modern wireless endoscope.The proposed multifunctional operation and unique radio transmission system cuts down the power consumption efficiently and on-demand bidirectional communication in vitro improves the detection rate of focus.Meanwhile,gray dilatation is introduced in a bit plane that optimizes the distortion rate in the process of image recording and transmission.

  10. Proposed pushered single shell capsule design for the investigation of mid/high Z mix on the NIF

    Science.gov (United States)

    Sacks, Ryan; Tipton, Robert; Graziani, Frank

    2016-05-01

    The CD Mix campaign has given a detailed explination of the mix mechanics in the current ignition capsule designs by investigating the relationship between material mixing, shell-fuel interfaces, and the change in thermonuclear yield given a deuterated layer in the capsule. Alternative ignition scenarios include the use of double shell designs that incorporate high-Z material in the capsule. Simulations are conducted on a proposed capsule platform using the ARES code on a scaled capsule design using a partially reduced glass capsule design. This allows for the inclusion of deuterium on the inner surface of the pusher layer similar to the CD mix experiments. The presence of silicon dioxide allows for the investigation of the influence of higher Z material on the mixing characteristics.

  11. Parametric Deformation of Discrete Geometry for Aerodynamic Shape Design

    Science.gov (United States)

    Anderson, George R.; Aftosmis, Michael J.; Nemec, Marian

    2012-01-01

    We present a versatile discrete geometry manipulation platform for aerospace vehicle shape optimization. The platform is based on the geometry kernel of an open-source modeling tool called Blender and offers access to four parametric deformation techniques: lattice, cage-based, skeletal, and direct manipulation. Custom deformation methods are implemented as plugins, and the kernel is controlled through a scripting interface. Surface sensitivities are provided to support gradient-based optimization. The platform architecture allows the use of geometry pipelines, where multiple modelers are used in sequence, enabling manipulation difficult or impossible to achieve with a constructive modeler or deformer alone. We implement an intuitive custom deformation method in which a set of surface points serve as the design variables and user-specified constraints are intrinsically satisfied. We test our geometry platform on several design examples using an aerodynamic design framework based on Cartesian grids. We examine inverse airfoil design and shape matching and perform lift-constrained drag minimization on an airfoil with thickness constraints. A transport wing-fuselage integration problem demonstrates the approach in 3D. In a final example, our platform is pipelined with a constructive modeler to parabolically sweep a wingtip while applying a 1-G loading deformation across the wingspan. This work is an important first step towards the larger goal of leveraging the investment of the graphics industry to improve the state-of-the-art in aerospace geometry tools.

  12. Development and Implementation of a Novel Parametrization Technique for Multidisciplinary Design Initialization

    NARCIS (Netherlands)

    Straathof, M.H.; Van Tooren, M.J.L.; Voskuijl, M.; Vos, R.

    2010-01-01

    A new parametrization method for aircraft shapes is presented to enhance shape optimization for aircraft design. This parametrization method was implemented in a tool that creates feasible initial solutions for multidisciplinary design optimization problems. The tool combines all aspects of the aero

  13. Interactive flutter analysis and parametric study for conceptual wing design

    Science.gov (United States)

    Mukhopadhyay, Vivek

    1995-01-01

    An interactive computer program was developed for wing flutter analysis in the conceptual design stage. The objective was to estimate the flutter instability boundary of a flexible cantilever wing, when well defined structural and aerodynamic data are not available, and then study the effect of change in Mach number, dynamic pressure, torsional frequency, sweep, mass ratio, aspect ratio, taper ratio, center of gravity, and pitch inertia, to guide the development of the concept. The software was developed on MathCad (trademark) platform for Macintosh, with integrated documentation, graphics, database and symbolic mathematics. The analysis method was based on nondimensional parametric plots of two primary flutter parameters, namely Regier number and Flutter number, with normalization factors based on torsional stiffness, sweep, mass ratio, aspect ratio, center of gravity location and pitch inertia radius of gyration. The plots were compiled in a Vaught Corporation report from a vast database of past experiments and wind tunnel tests. The computer program was utilized for flutter analysis of the outer wing of a Blended Wing Body concept, proposed by McDonnell Douglas Corporation. Using a set of assumed data, preliminary flutter boundary and flutter dynamic pressure variation with altitude, Mach number and torsional stiffness were determined.

  14. Comparison of Three Common Experimental Designs to Improve Statistical Power When Data Violate Parametric Assumptions.

    Science.gov (United States)

    Porter, Andrew C.; McSweeney, Maryellen

    A Monte Carlo technique was used to investigate the small sample goodness of fit and statistical power of several nonparametric tests and their parametric analogues when applied to data which violate parametric assumptions. The motivation was to facilitate choice among three designs, simple random assignment with and without a concomitant variable…

  15. Optimal Design of Experiments for Parametric Identification of Civil Engineering Structures

    DEFF Research Database (Denmark)

    Kirkegaard, Poul Henning

    Optimal Systems of experiments for parametric identification of civil engineering structures is investigated. Design of experiments for parametric identification of dynamic systems is usually done by minimizing a scalar measure, e.g the determinant, the trace ect., of an estimated parameter...

  16. Design of a video capsule endoscopy system with low-power ASIC for monitoring gastrointestinal tract.

    Science.gov (United States)

    Liu, Gang; Yan, Guozheng; Zhu, Bingquan; Lu, Li

    2016-11-01

    In recent years, wireless capsule endoscopy (WCE) has been a state-of-the-art tool to examine disorders of the human gastrointestinal tract painlessly. However, system miniaturization, enhancement of the image-data transfer rate and power consumption reduction for the capsule are still key challenges. In this paper, a video capsule endoscopy system with a low-power controlling and processing application-specific integrated circuit (ASIC) is designed and fabricated. In the design, these challenges are resolved by employing a microimage sensor, a novel radio frequency transmitter with an on-off keying modulation rate of 20 Mbps, and an ASIC structure that includes a clock management module, a power-efficient image compression module and a power management unit. An ASIC-based prototype capsule, which measures Φ11 mm × 25 mm, has been developed here. Test results show that the designed ASIC consumes much less power than most of the other WCE systems and that its total power consumption per frame is the least. The image compression module can realize high near-lossless compression rate (3.69) and high image quality (46.2 dB). The proposed system supports multi-spectral imaging, including white light imaging and autofluorescence imaging, at a maximum frame rate of 24 fps and with a resolution of 400 × 400. Tests and in vivo trials in pigs have proved the feasibility of the entire system, but further improvements in capsule control and compression performance inside the ASIC are needed in the future.

  17. Applied CATIA Secondary Development to Parametric Design of Active Magnetic Bearing

    Directory of Open Access Journals (Sweden)

    Zhang Li

    2016-01-01

    Full Text Available Based on the properties of active magnetic bearing, the electromagnetic parameters and structure parameters are analyzed, parametric design method is introduced to study the structure of active magnetic bearing. Through a program personalization process that is in accordance with active magnetic bearing is established. Personalization process aims to build the parametric model of active magnetic bearings and component library by use of CATIA secondary development. Component library is to build assembly model for a multiple degree of freedom magnetic bearing system. Parametric design is a method that provides the direction for its structural design.

  18. Integrating acoustic analysis in the architectural design process using parametric modelling

    DEFF Research Database (Denmark)

    Peters, Brady

    2011-01-01

    This paper discusses how parametric modeling techniques can be used to provide architectural designers with a better understanding of the acoustic performance of their designs and provide acoustic engineers with models that can be analyzed using computational acoustic analysis software. Architects...... are increasingly using parametric modeling techniques in their design processes to allow the exploration of large numbers of design options using multiple criteria. Parametric modeling software can be performance-driven and sound has the potential to become one of these performance-driven dimensions. This can...... provide a method by which architects and engineers can work together more efficiently and communicate better. This research is illustrated through the design of an architectural project, a new school in Copenhagen, Denmark by JJW Architects, where parametric modeling techniques have been used in different...

  19. Design and manufacturing of non-instrumented capsule for advanced PWR fuel pellet irradiation test in HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Kim, D. H.; Lee, C. B.; Song, K. W. [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2002-04-01

    This project is preparing to irradiation test of the developed large grain UO{sub 2} fuel pellet in HANARO for pursuit fuel safety and high burn-up in 'Advanced LWR Fuel Technology Development Project' as a part Nuclear Mid and Long-term R and D Program. On the basis test rod is performed the nuclei property and preliminary fuel performance analysis, test rod and non-instrumented capsule are designed and manufactured for irradiation test in HANARO. This non-instrumented irradiation capsule of Advanced PWR Fuel pellet was referred the non-instrumented capsule for an irradiation test of simulated DUPIC fuel in HANARO(DUPIC Rig-001) and 18-element HANARO fuel, was designed to ensure the integrity and the endurance of non-instrumented capsule during the long term(2.5 years) irradiation. To irradiate the UO{sub 2} pellets up to the burn-up 70 MWD/kgU, need the time about 60 months and ensure the integrity of non-instrumented capsule for 30 months until replace the new capsule. This non-instrumented irradiation capsule will be based to develope the non-instrumented capsule for the more long term irradiation in HANARO. 22 refs., 13 figs., 5 tabs. (Author)

  20. Parametric Design Optimization Of A Novel Permanent Magnet Coupling Using Finite Element Analysis

    DEFF Research Database (Denmark)

    Högberg, Stig; Mijatovic, Nenad; Holbøll, Joachim;

    2014-01-01

    A parametric design optimization routine has been applied to a novel magnetic coupling with improved recyclability. Coupling designs are modeled in a 3-D finite element environ- ment, and evaluated by three design objectives: pull-out torque, torque density by magnet mass, and torque density...

  1. Desiccant Enhanced Evaporative Air Conditioning: Parametric Analysis and Design; Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Woods, J.; Kozubal, E.

    2012-10-01

    This paper presents a parametric analysis using a numerical model of a new concept in desiccant and evaporative air conditioning. The concept consists of two stages: a liquid desiccant dehumidifier and a dew-point evaporative cooler. Each stage consists of stacked air channel pairs separated by a plastic sheet. In the first stage, a liquid desiccant film removes moisture from the process (supply-side) air through a membrane. An evaporatively-cooled exhaust airstream on the other side of the plastic sheet cools the desiccant. The second-stage indirect evaporative cooler sensibly cools the dried process air. We analyze the tradeoff between device size and energy efficiency. This tradeoff depends strongly on process air channel thicknesses, the ratio of first-stage to second-stage area, and the second-stage exhaust air flow rate. A sensitivity analysis reiterates the importance of the process air boundary layers and suggests a need for increasing airside heat and mass transfer enhancements.

  2. Systematic parametric design/calculation of the piston rod unit

    Science.gov (United States)

    Kacani, V.

    2015-08-01

    In this article a modern and economic method for the strength calculation of the piston rod unit and its components under different operating conditions will be presented. Herefore the commercial FEA - Software will be linked with the company-owned calculation tools. The parametric user input will be followed by an automatic Pre- and Postprocessing. Afterwards the strength calculation is processed on all critical points of the piston rod connection, assisted by an extra module, based on general standards and special codes for reciprocating compressors. In this process most arrangements of the piston rod unit as well as the special geometries of the single-components (piston, piston rod and piston nut) can be considered easily. In this article the modeling of the notches, especially on the piston rod, piston as well as the piston nut will be covered in detail.

  3. Research on Variable Structure Parametric Design System of Ceramic Tile Mould Based on Modular

    Institute of Scientific and Technical Information of China (English)

    DAI Xiao-bo; DONG Yu-de; QIN Lei

    2014-01-01

    To solve the existing problems during the ceramic mold enterprises product design and development process, the variable structure parametric design system based on modular of ceramic mold has been developed. The system uses the object-oriented technology and top-down design concept as a guide, establishes a ceramic mold parametric design process, divides the process of ceramic mold design into modules of different levels and creates a component model library based on the functional analysis. Expanding modular thinking to parts structure design level is an effective solution to the difficulty of changing the structure during the product design process. Examples show that the system can achieve a ceramic mold product design, improve design efficiency.

  4. Parametric design strategies: robotic building in academic architectural research and education

    NARCIS (Netherlands)

    Bier, H.H.

    2015-01-01

    Parametric design strategies employing design-to-robotic-production (D2RP) approaches are relative new in architecture. They require trans-disciplinary research that at Hyperbody, TUD is experimentally tested in academic education and research. This paper presents and discusses trans-disciplinary ap

  5. Parametric design and analysis framework with integrated dynamic models

    DEFF Research Database (Denmark)

    Negendahl, Kristoffer

    2014-01-01

    of building energy and indoor environment, are generally confined to late in the design process. Consequence based design is a framework intended for the early design stage. It involves interdisciplinary expertise that secures validity and quality assurance with a simulationist while sustaining autonomous...

  6. Design, Fabrication and Test Report on a Verification Capsule (05M-06K) for the Control of a Neutron Irradiation Fluence of Specimens in HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Choo, K. N.; Kim, B. G.; Kang, Y. H.; Cho, M. S.; Son, J. M.; Shin, Y. T.; Park, S. J.; Choi, M. H.; Lee, D. S.

    2007-02-15

    As a part of a project for a capsule development and utilization for an irradiation test, a verification capsule (05M-06K) was designed, fabricated and tested for the development of new instrumented capsule technology for a more precise control of the irradiation fluence of a specimen, irrespective of the reactor operation condition. The basic structure of the 05M-06K capsule was based on the 04M-22K mock-up capsule which was successfully designed and out-pile tested to confirm the various key technologies necessary for the fluence control of a specimen. 21 square and round shaped specimens made of STS 304 were inserted into the capsule. The capsule was constructed in 5 stages with specimens and an independent electric heater at each stage. Each of the five specimens which were accommodated in the 1st stage (top) of the capsule can be taken out of the HANARO core during a normal reactor operation. The specimen is extracted by a specimen extraction mechanism using a steel wire. During the out-pile test, the temperatures of the specimens were measured by 12 thermocouples installed in the capsule. The capsule was successfully out-pile tested in a single channel test loop. The obtained results will be used for a safety evaluation of the new irradiation capsule for controlling the irradiation fluence of specimens in HANARO.

  7. Asymmetric-shell ignition capsule design to tune the low-mode asymmetry during the peak drive

    Science.gov (United States)

    Gu, Jianfa; Dai, Zhensheng; Song, Peng; Zou, Shiyang; Ye, Wenhua; Zheng, Wudi; Gu, Peijun; Wang, Jianguo; Zhu, Shaoping

    2016-08-01

    The low-mode radiation flux asymmetry in the hohlraum is a main source of performance degradation in the National Ignition Facility (NIF) implosion experiments. To counteract the deleterious effects of the large positive P2 flux asymmetry during the peak drive, this paper develops a new tuning method called asymmetric-shell ignition capsule design which adopts the intentionally asymmetric CH ablator layer or deuterium-tritium (DT) ice layer. A series of two-dimensional implosion simulations have been performed, and the results show that the intentionally asymmetric DT ice layer can significantly improve the fuel ρR symmetry, hot spot shape, hot spot internal energy, and the final neutron yield compared to the spherical capsule. This indicates that the DT asymmetric-shell capsule design is an effective tuning method, while the CH ablator asymmetric-shell capsule could not correct the fuel ρR asymmetry, and it is not as effective as the DT asymmetric-shell capsule design.

  8. Parametric fuselage design: Integration of mechanics and acoustic & thermal insulation

    NARCIS (Netherlands)

    Krakers, L.A.

    2009-01-01

    Designing a fuselage is a very complex process, which involves many different aspects like strength and stability, fatigue, damage tolerance, fire resistance, thermal and acoustic insulation but also inspection, maintenance, production and repair aspects. It is difficult to include all design aspect

  9. Development of a WormCAD using Parametric Design Approach

    Directory of Open Access Journals (Sweden)

    Olayinka Oluwole Agboola

    2016-10-01

    Full Text Available Gears as power transmission devices are capable of changing the speed, torque, and direction of a power source and are considered to be one of the most important devices used in many types of machinery owing to their durability and higher power transmission efficiency. Worm gears as a type of gear are widely used for transmitting power at high velocity ratios between non-intersecting shafts. Worm gears are very useful in machine design but its design requires a lot of design assumptions and calculations. To achieve a rapid design devoid of errors, there is need to have a customized computer program capable of designing worm gears using standardized design equations; and that is what WormCAD stands for. The software was designed using JavaScript programming language and the Node.js platform. The WormCAD was tested to be accurate, faster and convenient hence it will be a viable software to be used by worm gear designers.

  10. Preliminary design and parametric study of 1400 m partially earth-anchored cable-stayed bridge

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The preliminary design and parametric study of 1400 m partially earth-anchored cable-stayed bridge are described. Static per-formance of this new type of bridge is discussed. Compared with fully self-anchored cable-stayed bridge, its advantages in fin-ished state are summarized. Based on numerical calculation, effects of several structural parameters on static performance are presented.

  11. Design and Parametr Analysis of Switched Reluctance Motor with Permanent Magnets

    Directory of Open Access Journals (Sweden)

    Ivan Trak

    2004-01-01

    Full Text Available This paper deals with Switched Reluctance Motor (SRM parametr investigation, if permanent magnets are suitable inserted in stator parts to increase magnetic flux. The analysis is made on the base of input geometrical dimensions and materials of a real SRM without permanent magnets (PM. The calculation of PMSRM static parametres is made by means of Finite Element Method (FEM and by analytical approach. The output parameters of PMSRM analysis are phase inductance, flux linage and electromagnetic torque versus phase current and rotor position. These calculated parameters are compared with measured and FEM calculated parameters of SRM without PM. The recommendations for PMSRM design configuration are given.

  12. Parametric study for the fire safety design of steel structures

    DEFF Research Database (Denmark)

    Aiuti, Riccardo; Giuliani, Luisa

    2013-01-01

    and find out the basic collapse mechanisms of structural elements in fire conditions, considering the rest of the construction with appropriate constraints. The analysis is carried out taking into account material and geometrical nonlinearities as well as the degradation of steel properties at high......Despite the increasing knowledge on the behaviour of structures in fire and the development of new design tools for fire safety, current prescriptive regulations and design procedures present several shortcomings. These are mostly due to an oversimplification of the problem, in order to allow...... for a simple integration of the fire design procedures in the common practice. In this view, the structural fire safety of a building can be accomplished by verifying that single elements can resist a standard fire exposure for a required time, without taking into consideration the effect of restrained...

  13. Parametric Design of Injectors for LDI-3 Combustors

    Science.gov (United States)

    Ajmani, Kumud; Mongia, Hukam; Lee, Phil

    2015-01-01

    Application of a partially calibrated National Combustion Code (NCC) for providing guidance in the design of the 3rd generation of the Lean-Direct Injection (LDI) multi-element combustion configuration (LDI-3) is summarized. NCC was used to perform non-reacting and two-phase reacting flow computations on several LDI-3 injector configurations in a single-element and a five-element injector array. All computations were performed with a consistent approach for mesh-generation, turbulence, spray simulations, ignition and chemical kinetics-modeling. Both qualitative and quantitative assessment of the computed flowfield characteristics of the several design options led to selection of an optimal injector LDI- 3 design that met all the requirements including effective area, aerodynamics and fuel-air mixing criteria. Computed LDI-3 emissions (namely, NOx, CO and UHC) will be compared with the prior generation LDI- 2 combustor experimental data at relevant engine cycle conditions.

  14. Observer design for matrix second order linear systems with uncertain disturbance input-a parametric approach

    Institute of Scientific and Technical Information of China (English)

    Wu Yunli; Li Zhibin; Duan Guangren

    2006-01-01

    A simple parametric approach to design a full-order observer for matrix second-order linear systems with uncertain disturbance input in the matrixsecond-order framework is proposed. The basic idea is to minimize the H2 norm of the transfer function from disturbance to estimation error using the design degrees of freedom provided by a parametric approach in the observer design. Besides the design parameters, the eigenvalues of the closed-loop system are also optimized within desired regions on the left-half of the complex plane. Using the proposed approach, additional specifications can be easily achieved. A spring-mass system is using to show the effect of the proposed approaches.

  15. Parametric design studies of toroidal magnetic energy storage units

    Science.gov (United States)

    Herring, J. Stephen

    Superconducting magnetic energy storage (SMES) units have a number of advantages as storage devices. Electrical current is the input, output and stored medium, allowing for completely solid-state energy conversion. The magnets themselves have no moving parts. The round trip efficiency is higher than those for batteries, compressed air or pumped hydro. Output power can be very high, allowing complete discharge of the unit within a few seconds. Finally, the unit can be designed for a very large number of cycles, limited basically by fatigue in the structural components. A small systems code was written to produce and evaluate self-consistent designs for toroidal superconducting energy storage units. The units can use either low temperature or high temperature superconductors. The coils have D shape where the conductor and its stabilizer/structure is loaded only in tension and the centering forces are borne by a bucking cylinder. The coils are convectively cooled from a cryogenic reservoir in the bore of the coils. The coils are suspended in a cylindrical metal shell which protects the magnet during rail, automotive or shipboard use. It is important to note that the storage unit does not rely on its surroundings for structural support, other than normal gravity and inertial loads. Designs are presented for toroidal energy storage units produced by the systems code. A wide range of several parameters have been considered, resulting in units storing from 1 MJ to 72 GJ. Maximum fields range from 5 T to 20 T. The masses and volumes of the coils, bucking cylinder, coolant, insulation and outer shell are calculated. For unattended use, the allowable operating time using only the boiloff of the cryogenic fluid for refrigeration is calculated. For larger units, the coils were divided into modules suitable for normal truck or rail transport.

  16. Design and Numerical Parametric Study of Fractal Heat Exchanger

    OpenAIRE

    Huang, Zhiwei; Ling, Jiazhen; Hwang, Yunho; Aute, Vikrant; Radermacher, Reinhard

    2016-01-01

    Air-to-refrigerant heat exchangers are a main component in air-conditioning and heat pump systems and are therefore a topic of major research focus. Such heat exchangers, mainly made of fin-and-tube and microchannels, use fins to augment the heat transfer area of the air-side. Recently it has been shown that finless designs using ≤ 1 mm hydraulic diameter bare tubes can deliver better air-side heat transfer performance than conventional heat exchangers. In current study, a novel air-to-refr...

  17. Parametric study of turbine NGV blade lean and vortex design

    Directory of Open Access Journals (Sweden)

    Zhang Shaowen

    2016-02-01

    Full Text Available The effects of blade lean and vortex design on the aerodynamics of a turbine entry nozzle guide vane (NGV are considered using computational fluid dynamics. The aim of the work is to address some of the uncertainties which have arisen from previous studies where conflicting results have been reported for the effect on the NGV. The configuration was initially based on the energy efficient engine turbine which also served as the validation case for the computational method. A total of 17 NGV configurations were evaluated to study the effects of lean and vortex design on row efficiency and secondary kinetic energy. The distribution of mass flow ratio is introduced as an additional factor in the assessment of blade lean effects. The results show that in the turbine entry NGV, the secondary flow strength is not a dominant factor that determines NGV losses and therefore the changes of loading distribution due to blade lean and the associated loss mechanisms should be regarded as a key factor. Radial mass flow redistribution under different NGV lean and twist is demonstrated as an addition key factor influencing row efficiency.

  18. Parametric study of turbine NGV blade lean and vortex design

    Institute of Scientific and Technical Information of China (English)

    Zhang Shaowen; David G. MacManus; Luo Jianqiao

    2016-01-01

    The effects of blade lean and vortex design on the aerodynamics of a turbine entry nozzle guide vane (NGV) are considered using computational fluid dynamics. The aim of the work is to address some of the uncertainties which have arisen from previous studies where conflicting results have been reported for the effect on the NGV. The configuration was initially based on the energy efficient engine turbine which also served as the validation case for the computational method. A total of 17 NGV configurations were evaluated to study the effects of lean and vortex design on row efficiency and secondary kinetic energy. The distribution of mass flow ratio is introduced as an additional factor in the assessment of blade lean effects. The results show that in the turbine entry NGV, the secondary flow strength is not a dominant factor that determines NGV losses and therefore the changes of loading distribution due to blade lean and the associated loss mecha-nisms should be regarded as a key factor. Radial mass flow redistribution under different NGV lean and twist is demonstrated as an addition key factor influencing row efficiency.

  19. Status Report on Irradiation Capsules Designed to Evaluate FeCrAl-UO2 Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Field, Kevin G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Howard, Richard H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-06-24

    This status report provides the background and current status of a series of irradiation capsules that were designed and are being built to test the interactions between candidate FeCrAl cladding for enhanced accident tolerant applications and prototypical enriched commercial UO2 fuel in a neutron radiation environment. These capsules will test the degree, if any, of fuel cladding chemical interactions (FCCI) between FeCrAl and UO2. The capsules are to be irradiated in the Advanced Test Reactor (ATR) at Idaho National Laboratory to burn-ups of 10, 30, and 50 GWd/MT with a nominal target temperature at the interfaces between the pellets and clad of 350°C.

  20. Design and statistical optimization of osmotically driven capsule based on push-pull technology.

    Science.gov (United States)

    Shaikh, Wasim; Deshmukh, Prashant K; Patil, Ganesh B; Chatap, Vivekanand K; Bari, Sanjay B

    2013-01-01

    In present investigation attempt was made to develop and statistically optimize osmotically active capsule tailor made from the concept of bilayer (push-pull) osmotic tablet technology. The capsule was comprised of active (drug) and push (osmogen) layer. Active layer was compressed in form of tablet by mixing known amount of drug and formulation excipients. Similarly push layer was made by compressing Mannitol with formulation excipients. Finally, both layers were packed in hard gelatin capsule having small aperture at top and coated with semipermeable membrane to form osmotically active capsule. Formulated and optimized capsules were characterized for Fourier transform infrared (FT-IR) spectroscopy, differential scanning calorimetric (DSC), scanning electron microscopy, In-vitro drug release study and Release models and kinetics. Statistically optimized formulation showed good correlation between predicted and experimented results, which further confirms the practicability and validity of the model.

  1. Parametric design of an electrorheological shock absorber with the mixed-mode

    Institute of Scientific and Technical Information of China (English)

    ZHENG Ling; DENG Zhaoxiang; LI Yinong

    2003-01-01

    A mathematical model based on an electrorheological (ER) shock absorber with the mixed-mode is presented. Its application to the parametric design of an electrorheological fluid shock absorber with the simulation calculation performed by program MATLAB demonstrates that the model can predict the behavior of ER shock absorbers satisfactorily, shorten the design period of an electrorheological shock absorber, and reduce the cost in the prototype manufacturing. The strength analysis based on a three-dimensional finite element model for the electrorheological shock absorber confirm that the structure design of the ER shock absorber is reasonable, and the stress distribution is uniform.

  2. Design of parametric fault detection systems:An H-infinity optimization approach

    Institute of Scientific and Technical Information of China (English)

    Maiying ZHONG; Chuanfeng MA; Steven X.DING

    2005-01-01

    Problems related to the design of observer-based parametric fault detection (PFD) systems are studied.The core of our study is to first describe the faults occurring in system actuators,sensors and components in the form of additive parameter deviations,then to transform the PFD problems into a similar additive fault setup,based on which an optimal observer-based optimization fault detection approach is proposed.A constructive solution optimal in the sense of minimizing a certain performance index is developed.The main results consist of defining parametric fault detectability,formulating a PFD optimization problem and its solution.A numerical example to demonstrate the effectiveness of the proposed approach is provided.

  3. Facilitating Performance Optimization of RF PCB Designs by using Parametric Finite-Element Component Models

    DEFF Research Database (Denmark)

    Rohde, John; Toftegaard, Thomas Skjødeberg

    2012-01-01

    Novel parametric finite-element models are provided for discrete SMD capacitors and inductors in the frequency range 100 MHz to 4 GHz. The aim of the models is to facilitate performance optimization and analysis of RF PCB designs integrating these SMD components with layout geometries...... such as antennas and PCB traces. The models presented are benchmarked against real-life measurements and conventional circuit models. Furthermore, two example parallel-resonance circuits are designed based on interpolation of the results and validated by measurements in order to demonstrate the accuracy...... of the presented modelling approach....

  4. A Parametric Study for High-Efficiency Gas-Liquid Separator Design

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A gas liquid centrifugal separator is widely used in industry on account of its simple geometry and little maintenance. These separators have considerable advantages over filters, scrubbers or precipitators in term of compact design, lower pressure drop and higher capacity. A gas liquid centrifugal separator is a device that utilizes centrifugal forces and low pressure caused by rotational motion to separate liquid from gas by density differences.Efficient and reliable separation is required for the optimum operation. These separators axe often operated at less than peak efficiency due to the entrainment of separated liquid through an outlet pipe which is closely associated with the very complicated flow phenomena involved. Design parameters such as length of the separation space,vane exit angle, inlet to outlet diameter ratio, models for separation efficiency and pressure drop as a function of physical dimensions are not available in literature. This leaves the designer with very little to go on except known designs and experimentation. The aim of present study is to perform a parametric study to get higher efficiency for gas-liquid separator. A parametric study has been carried out with the help of CFD tools to analyze a separation performance of a centrifugal separator by varying the length of separator space. The best design parameters are analyzed based upon obtained results, tangential velocities, vortices, total pressure losses. From the present study several attempts are made to improve the performance of conventional centrifugal separators.

  5. Design and testing of a boron carbide capsule for spectral-tailoring in mixed-spectrum reactors

    Energy Technology Data Exchange (ETDEWEB)

    Greenwood, L.R.; Wittman, R. [Pacific Northwest National Laboratory, Richland, WA 99352 (United States); Pierson, B.P. [Univ. of Michigan, Ann Arbor, MI 48109 (United States); Metz, L.A.; Payne, R.; Finn, E.C.; Friese, J.I. [Pacific Northwest National Laboratory, Richland, WA 99352 (United States)

    2011-07-01

    A boron carbide capsule has been designed and used for spectral-tailoring experiments at the TRIGA reactor at Washington State Univ.. Irradiations were conducted in pulsed mode and in continuous operation for up to 4 h. A cadmium cover was used to reduce thermal heating. The neutron spectrum calculated with the Monte Carlo N-particle transport code was found to be in good agreement with reactor dosimetry measurements using the STAY'SL computer code. The neutron spectrum resembles that of a fast reactor. The design of a capsule using boron carbide fully enriched in {sup 10}B shows that it is possible to produce a neutron spectrum similar to that of {sup 235}U fission. (authors)

  6. Brayton power conversion system parametric design modelling for nuclear electric propulsion

    Science.gov (United States)

    Ashe, Thomas L.; Otting, William D.

    1993-11-01

    The parametrically based closed Brayton cycle (CBC) computer design model was developed for inclusion into the NASA LeRC overall Nuclear Electric Propulsion (NEP) end-to-end systems model. The code is intended to provide greater depth to the NEP system modeling which is required to more accurately predict the impact of specific technology on system performance. The CBC model is parametrically based to allow for conducting detailed optimization studies and to provide for easy integration into an overall optimizer driver routine. The power conversion model includes the modeling of the turbines, alternators, compressors, ducting, and heat exchangers (hot-side heat exchanger and recuperator). The code predicts performance to significant detail. The system characteristics determined include estimates of mass, efficiency, and the characteristic dimensions of the major power conversion system components. These characteristics are parametrically modeled as a function of input parameters such as the aerodynamic configuration (axial or radial), turbine inlet temperature, cycle temperature ratio, power level, lifetime, materials, and redundancy.

  7. Design and fabrication report on instrumented capsule (99M-01K.02H) for korean reactor pressure vessel material made by HANJUNG (Co)

    Energy Technology Data Exchange (ETDEWEB)

    Choo, K. N.; Kang, Y. H.; Kim, B. G.; Cho, M. S.; Son, J. M.; Kim, D. S.; Oh, J. M.; Park, S. J.; Shin, Y. T

    2000-09-01

    The instrumented capsules (99M-01K{center_dot}02H) was designed and fabricated. The purpose of the capsules were to evaluate the nuclear irradiation performance of the Korean nuclear reactor pressure vessel material, SA508 class 3 steel, fabricated by HANJUNG Co for Yonggwang Units 4,5 and Ulchin Unit 4. There are 5 stages having specimens and independent electric heaters in the capsule mainbody. 12 K-type thermocouples and 5 sets of Ni-Ti-Fe and sapphire neutron Fluence Monitors were also inserted in the apsule. Various types of specimens, such as round compact tension, Charpy insert, pre-cracked v-notch (PCVN), tensile, small punch (SP), magnetic Barkhausen effect (MBE), and transmission electron micrograph (TEM) specimens, were inserted in the capsule. The capsule was fabricated at DAEWOO Precision Co. according to KAERI detailed design specifications. This report describes the details of the design, fabrication and inspection of the 99M-01K and 99M-02H capsule. The capsules were irradiated in the IR2 test hole of HANARO at 290{+-}10 deg C up to the fast neutron fluence (E>1.0 MeV) of 3.0x10{sup 19} (n/cm{sup 2})

  8. Unified parametric approaches for high-order integral observer design for matrix second-order linear systems

    Institute of Scientific and Technical Information of China (English)

    Guangren DUAN; Yunli WU

    2006-01-01

    A type of high-order integral observers for matrix second-order linear systems is proposed on the basis of generalized eigenstructure assignment via unified parametric approaches. Through establishing two general parametric solutions to this type of generalized matrix second-order Sylvester matrix equations, two unified complete parametric methods for the proposed observer design problem are presented. Both methods give simple complete parametric expressions for the observer gain matrices. The first one mainly depends on a series of singular value decompositions, and is thus numerically simple and reliable; the second one utilizes the right factorization of the system, and allows eigenvalues of the error system to be set undetermined and sought via certain optimization procedures. A spring-mass-dashpot system is utilized to illustrate the design procedure and show the effect of the proposed approach.

  9. A Novel Computer-Aided Approach for Parametric Investigation of Custom Design of Fracture Fixation Plates

    Science.gov (United States)

    2017-01-01

    The present study proposes an integrated computer-aided approach combining femur surface modeling, fracture evidence recover plate creation, and plate modification in order to conduct a parametric investigation of the design of custom plate for a specific patient. The study allows for improving the design efficiency of specific plates on the patients' femur parameters and the fracture information. Furthermore, the present approach will lead to exploration of plate modification and optimization. The three-dimensional (3D) surface model of a detailed femur and the corresponding fixation plate were represented with high-level feature parameters, and the shape of the specific plate was recursively modified in order to obtain the optimal plate for a specific patient. The proposed approach was tested and verified on a case study, and it could be helpful for orthopedic surgeons to design and modify the plate in order to fit the specific femur anatomy and the fracture information. PMID:28203270

  10. Parametric Study and Design Optimization of Centrifugal Pump Impeller-A Review

    Directory of Open Access Journals (Sweden)

    Vijaypratap R Singh ,

    2014-01-01

    Full Text Available Centrifugal pumps are widely used for irrigation, water supply plants, steam power plants, sewage, oil refineries, chemical plants, hydraulic power service, food processing factories and mines, because of their suitability in practically any service. Therefore it is necessary to find out the design parameters and working conditions that yield optimal output and maximum efficiency with lowest power consumption. Study indicates that Computational fluid dynamics (CFD analysis is being increasingly applied in the design of centrifugal pumps. With the aid of the CFD approach, the complex internal flows in water pump impellers, can be well predicted, to speed up the pump design procedure. This paper exposes the various research work carried out in this direction especially in the content of parametric study and optimization of centrifugal pump impeller using CFD tool and DoE technique. Literature surveys indicate that very restricted work has been done in this area.

  11. Parametric Optimal Design of a Parallel Schönflies-Motion Robot under Pick-And-Place Trajectory Constraints

    DEFF Research Database (Denmark)

    Wu, Guanglei; Bai, Shaoping; Hjørnet, Preben

    2015-01-01

    This paper deals with the parametric optimum design of a parallel Schoenflies-motion robot, named "Ragnar", designed for fast and flexible pick-and-place applications. The robot architecture admits a rectangular workspace, which can utilize the shop-floor space efficiently. In this work, the para......This paper deals with the parametric optimum design of a parallel Schoenflies-motion robot, named "Ragnar", designed for fast and flexible pick-and-place applications. The robot architecture admits a rectangular workspace, which can utilize the shop-floor space efficiently. In this work......, the parametric models of the transmission quality, elasto-statics and dynamics are established. By taking into consideration of design requirements and pick-and-place trajectory, a comprehensive multi-objective optimization problem is formulated to optimize both kinematic and dynamic performances. The Pareto...

  12. PM Motor Parametric Design Analyses for Hybrid Electric Vehicle Traction Drive Application: Interim Report

    Energy Technology Data Exchange (ETDEWEB)

    Staunton, R.H.

    2004-08-11

    The Department of Energy's (DOE) Office of FreedomCAR (Cooperative Automotive Research) and Vehicle Technologies has a strong interest in making rapid progress in permanent magnet (PM) machine development. The program is directing various technology development projects that will advance the technology and lead to request for proposals (RFP) for manufacturer prototypes. This aggressive approach is possible because the technology is clearly within reach and the approach is deemed essential, based on strong market demand, escalating fuel prices, and competitive considerations. In response, this study began parallel development paths that included a literature search/review, development and utilization of multiple parametric models to determine the effects of design parameters, verification of the modeling methodology, development of an interior PM (IPM) machine baseline design, development of alternative machine baseline designs, and cost analyses for several candidate machines. This interim progress report summarizes the results of these activities as of June 2004. This report provides background and summary information for recent machine parametric studies and testing programs that demonstrate both the potential capabilities and technical limitations of brushless PM machines (axial gap and radial gap), the IPM machine, the surface-mount PM machines (interior or exterior rotor), induction machines, and switched reluctance machines. The FreedomCAR program, while acknowledging the progress made by Oak Ridge National Laboratory, Delphi, Delco-Remy International, and others in these programs, has redirected efforts toward a ''short path'' to a marketable and competitive PM motor for hybrid electric vehicle traction applications. The program has developed a set of performance targets for the type of traction machine desired. The short-path approach entails a comprehensive design effort focusing on the IPM machine and meeting the performance

  13. Design, fabrication and irradiation test report on HANARO instrumented capsule (05M-07U) for the researches of universities in 2005

    Energy Technology Data Exchange (ETDEWEB)

    Choo, K. N.; Kim, B. G.; Kang, Y. H.; Choi, M. H.; Cho, M. S.; Son, J. M.; Choi, M. H.; Shin, Y. T.; Park, S. J.

    2006-09-15

    As a part of the 2005 project for an active utilization of HANARO, an instrumented capsule (05M-07U) was designed, fabricated and irradiated for an irradiation test of various unclear materials under irradiation conditions which was requested by external researchers from universities. The basic structure of the 05M-07U capsule was based on the 00M-01U, 01M-05U, 02M-05U, 03M-06U and 04M-07U capsules which had been successfully irradiated in HANARO as part of the 2000, 2001, 2002, 2003 and 2004 projects. However, because of a limited number of specimens and the budget of one university, the remaining space in the capsule was filled with various KAERI specimens for researches on a nuclear core and SMART materials, and parts of a nuclear fuel assembly of KNFC. Various types of specimens such as tensile, Charpy, TEM, hardness, compression and growth specimens made of Zr 702, Ti and Ni alloys, Zirlo, Inconel, STS 316L and Cr-Mo alloys were placed in the capsule. Especially, this capsule was designed to evaluate the nuclear characteristics of the parts of a nuclear fuel assembly and the Ti tubes in HANARO. The capsule was composed of 5 stages having many kinds of specimens and an independent electric heater at each stage. During the irradiation test, the temperature of the specimens and the thermal/fast neutron fluences were measured by 14 thermocouples and 5 sets of Ni-Ti-Fe neutron fluence monitors installed in the capsule. The capsule was irradiated in the CT test hole of HANARO of a 30MW thermal output at 270 ∼ 400 .deg. C up to a fast neutron fluence of 5.7 x 10{sup 20} (n/cm{sup 2}) (E >1.0MeV). The obtained results will be very valuable for the related research of the users.

  14. A Conceptual Wing Flutter Analysis Tool for Systems Analysis and Parametric Design Study

    Science.gov (United States)

    Mukhopadhyay, Vivek

    2003-01-01

    An interactive computer program was developed for wing flutter analysis in the conceptual design stage. The objective was to estimate flutt er instability boundaries of a typical wing, when detailed structural and aerodynamic data are not available. Effects of change in key flu tter parameters can also be estimated in order to guide the conceptual design. This userfriendly software was developed using MathCad and M atlab codes. The analysis method was based on non-dimensional paramet ric plots of two primary flutter parameters, namely Regier number and Flutter number, with normalization factors based on wing torsion stiffness, sweep, mass ratio, taper ratio, aspect ratio, center of gravit y location and pitch-inertia radius of gyration. These parametric plo ts were compiled in a Chance-Vought Corporation report from database of past experiments and wind tunnel test results. An example was prese nted for conceptual flutter analysis of outer-wing of a Blended-Wing- Body aircraft.

  15. PM Motor Parametric Design Analyses for a Hybrid Electric Vehicle Traction Drive Application

    Energy Technology Data Exchange (ETDEWEB)

    Staunton, R.H.

    2004-10-11

    The Department of Energy's (DOE) Office of FreedomCAR (Cooperative Automotive Research) and Vehicle Technologies office has a strong interest in making rapid progress in permanent magnet (PM) machine development. The DOE FreedomCAR program is directing various technology development projects that will advance the technology and hopefully lead to a near-term request for proposals (RFP) for a to-be-determined level of initial production. This aggressive approach is possible because the technology is clearly within reach and the approach is deemed essential, based on strong market demand, escalating fuel prices, and competitive considerations. In response, this study began parallel development paths that included a literature search/review, development and utilization of multiple parametric models, verification of the modeling methodology, development of an interior PM (IPM) machine baseline design, development of alternative machine baseline designs, and cost analyses for several candidate machines. This report summarizes the results of these activities as of September 2004. This report provides background and summary information for recent machine parametric studies and testing programs that demonstrate both the potential capabilities and technical limitations of brushless PM machines (axial gap and radial gap), the IPM machine, the surface-mount PM machines (interior or exterior rotor), induction machines, and switched-reluctance machines. The FreedomCAR program, while acknowledging the progress made by Oak Ridge National Laboratory (ORNL), Delphi, Delco-Remy International, and others in these programs, has redirected efforts toward a ''short path'' to a marketable and competitive PM motor for hybrid electric vehicle (HEV) traction applications. The program has developed a set of performance targets for the type of traction machine desired. The short-path approach entails a comprehensive design effort focusing on the IPM machine and meeting

  16. Performance Driven Design and Design Information Exchange: Establishing a computational design methodology for parametric and performance-driven design of structures via topology optimization for rough structurally informed design models

    NARCIS (Netherlands)

    Mostafavi, S.; Morales Beltran, M.G.; Biloria, N.M.

    2013-01-01

    This paper presents a performance driven computational design methodology through introducing a case on parametric structural design. The paper describes the process of design technology development and frames a design methodology through which engineering, -in this case structural- aspects of archi

  17. An Expert System-Driven Method for Parametric Trajectory Optimization During Conceptual Design

    Science.gov (United States)

    Dees, Patrick D.; Zwack, Mathew R.; Steffens, Michael; Edwards, Stephen; Diaz, Manuel J.; Holt, James B.

    2015-01-01

    . The methodology is two-fold: first, capture the heuristics developed by human analysts over their many years of experience; and secondly, leverage the power of modern computing to evaluate multiple trajectories simultaneously and therefore enable the exploration of the trajectory's design space early during the pre- conceptual and conceptual phases of design. This methodology is coupled with design of experiments in order to train surrogate models, which enables trajectory design space visualization and parametric optimal ascent trajectory information to be available when early design decisions are being made.

  18. A Novel Parametric Modeling Method and Optimal Design for Savonius Wind Turbines

    Directory of Open Access Journals (Sweden)

    Baoshou Zhang

    2017-03-01

    Full Text Available Under the inspiration of polar coordinates, a novel parametric modeling and optimization method for Savonius wind turbines was proposed to obtain the highest power output, in which a quadratic polynomial curve was bent to describe a blade. Only two design parameters are needed for the shape-complicated blade. Therefore, this novel method reduces sampling scale. A series of transient simulations was run to get the optimal performance coefficient (power coefficient C p for different modified turbines based on computational fluid dynamics (CFD method. Then, a global response surface model and a more precise local response surface model were created according to Kriging Method. These models defined the relationship between optimization objective Cp and design parameters. Particle swarm optimization (PSO algorithm was applied to find the optimal design based on these response surface models. Finally, the optimal Savonius blade shaped like a “hook” was obtained. Cm (torque coefficient, Cp and flow structure were compared for the optimal design and the classical design. The results demonstrate that the optimal Savonius turbine has excellent comprehensive performance. The power coefficient Cp is significantly increased from 0.247 to 0.262 (6% higher. The weight of the optimal blade is reduced by 17.9%.

  19. Body Bias usage in UTBB FDSOI designs: A parametric exploration approach

    Science.gov (United States)

    Puschini, Diego; Rodas, Jorge; Beigne, Edith; Altieri, Mauricio; Lesecq, Suzanne

    2016-03-01

    Some years ago, UTBB FDSOI has appeared in the horizon of low-power circuit designers. With the 14 nm and 10 nm nodes in the road-map, the industrialized 28 nm platform promises highly efficient designs with Ultra-Wide Voltage Range (UWVR) thanks to extended Body Bias properties. From the power management perspective, this new opportunity is considered as a new degree of freedom in addition to the classic Dynamic Voltage Scaling (DVS), increasing the complexity of the power optimization problem at design time. However, so far no formal or empiric tool allows to early evaluate the real need for a Dynamic Body Bias (DBB) mechanism on future designs. This paper presents a parametric exploration approach that analyzes the benefits of using Body Bias in 28 nm UTBB FDSOI circuits. The exploration is based on electrical simulations of a ring-oscillator structure. These experiences show that a Body Bias strategy is not always required but, they underline the large power reduction that can be achieved when mandatory. Results are summarized in order to help designers to analyze how to choose the best dynamic power management strategy for a given set of operating conditions in terms of temperature, circuit activity and process choice. This exploration contributes to the identification of conditions that make DBB more efficient than DVS, and vice versa, and when both methods are mandatory to optimize power consumption.

  20. Space capsule recovery—Evaluation of risk factors, safety plans and procedures and design of experiments for systems qualification

    Science.gov (United States)

    Narasaiah, N.; Varaprasad, R.; Seshagiri Rao, V.; Krishnamurty, V.; Sanyal, M. K.

    2009-11-01

    The Indian Space capsule (SRE-1) launched aboard PSLV-C7 rocket, was recovered successfully in the Bay of Bengal on January 22, 2007 after its orbital sojourn of 12 days. Apart from serving as a platform for micro-gravity experiments, SRE-1 demonstrated ISRO's capability in the field of orbital reentry and recovery technologies. Satish Dhawan Space Centre (SDSC SHAR), the Spaceport of India was given the prime responsibility of assessment of mission risk, formulation and execution of safety plans and procedures, design and conduct of trials for validating the mission-critical sub-systems as well as the physical recovery of the capsule. To achieve these objectives, a number of drop tests were designed and conducted by SDSC SHAR involving real time computer network, ground-based tracking and telemetry stations, communication systems, safety and material handling systems, target identification and recovery systems. Dissemination of relevant information and coordination with multiple external organizations such as Indian Coast Guard, Indian Air Force and Indian Navy is an important aspect of these experiments. This paper delineates the methodologies designed and implemented at SDSC SHAR for validating those critical systems whose functionality finally culminated in the success of the mission, enabling India to join the elite group of nations with reentry module recovery capability.

  1. Capsule endoscopy

    Science.gov (United States)

    ... It is about the size of a large vitamin pill. The person swallows the capsule, and it takes pictures all the way through ... can be started in the doctor's office. The capsule is the size of a large vitamin pill, about an inch (2.5 centimeters) long ...

  2. Frequency domain analysis and design of nonlinear systems based on Volterra series expansion a parametric characteristic approach

    CERN Document Server

    Jing, Xingjian

    2015-01-01

    This book is a systematic summary of some new advances in the area of nonlinear analysis and design in the frequency domain, focusing on the application oriented theory and methods based on the GFRF concept, which is mainly done by the author in the past 8 years. The main results are formulated uniformly with a parametric characteristic approach, which provides a convenient and novel insight into nonlinear influence on system output response in terms of characteristic parameters and thus facilitate nonlinear analysis and design in the frequency domain.  The book starts with a brief introduction to the background of nonlinear analysis in the frequency domain, followed by recursive algorithms for computation of GFRFs for different parametric models, and nonlinear output frequency properties. Thereafter the parametric characteristic analysis method is introduced, which leads to the new understanding and formulation of the GFRFs, and nonlinear characteristic output spectrum (nCOS) and the nCOS based analysis a...

  3. Design and Parametric Sizing of Deep Space Habitats Supporting NASA'S Human Space Flight Architecture Team

    Science.gov (United States)

    Toups, Larry; Simon, Matthew; Smitherman, David; Spexarth, Gary

    2012-01-01

    NASA's Human Space Flight Architecture Team (HAT) is a multi-disciplinary, cross-agency study team that conducts strategic analysis of integrated development approaches for human and robotic space exploration architectures. During each analysis cycle, HAT iterates and refines the definition of design reference missions (DRMs), which inform the definition of a set of integrated capabilities required to explore multiple destinations. An important capability identified in this capability-driven approach is habitation, which is necessary for crewmembers to live and work effectively during long duration transits to and operations at exploration destinations beyond Low Earth Orbit (LEO). This capability is captured by an element referred to as the Deep Space Habitat (DSH), which provides all equipment and resources for the functions required to support crew safety, health, and work including: life support, food preparation, waste management, sleep quarters, and housekeeping.The purpose of this paper is to describe the design of the DSH capable of supporting crew during exploration missions. First, the paper describes the functionality required in a DSH to support the HAT defined exploration missions, the parameters affecting its design, and the assumptions used in the sizing of the habitat. Then, the process used for arriving at parametric sizing estimates to support additional HAT analyses is detailed. Finally, results from the HAT Cycle C DSH sizing are presented followed by a brief description of the remaining design trades and technological advancements necessary to enable the exploration habitation capability.

  4. Parametric Design and Multiobjective Optimization of Maglev Actuators for Active Vibration Isolation System

    Directory of Open Access Journals (Sweden)

    Qianqian Wu

    2014-05-01

    Full Text Available The microvibration has a serious impact on science experiments on the space station and on image quality of high resolution satellites. As an important component of the active vibration isolation platform, the maglev actuator has a large stroke and exhibits excellent isolating performance benefiting from its noncontact characteristic. A maglev actuator with good linearity was designed in this paper. Fundamental features of the maglev actuator were obtained by finite element simulation. In order to minimize the coil weight and the heat dissipation of the maglev actuator, parametric design was carried out and multiobjective optimization based on the genetic algorithm was adopted. The optimized actuator has better mechanical properties than the initial one. Active vibration isolation platforms for different-scale payload were designed by changing the arrangement of the maglev actuators. The prototype to isolate vibration for small-scale payload was manufactured and the experiments for verifying the characteristics of the actuators were set up. The linearity of the actuator and the mechanical dynamic response of the vibration isolation platform were obtained. The experimental results highlight the effectiveness of the proposed design.

  5. Design, parametrization, and pole placement of stabilizing output feedback compensators via injective cogenerator quotient signal modules.

    Science.gov (United States)

    Blumthaler, Ingrid; Oberst, Ulrich

    2012-03-01

    Control design belongs to the most important and difficult tasks of control engineering and has therefore been treated by many prominent researchers and in many textbooks, the systems being generally described by their transfer matrices or by Rosenbrock equations and more recently also as behaviors. Our approach to controller design uses, in addition to the ideas of our predecessors on coprime factorizations of transfer matrices and on the parametrization of stabilizing compensators, a new mathematical technique which enables simpler design and also new theorems in spite of the many outstanding results of the literature: (1) We use an injective cogenerator signal module ℱ over the polynomial algebra [Formula: see text] (F an infinite field), a saturated multiplicatively closed set T of stable polynomials and its quotient ring [Formula: see text] of stable rational functions. This enables the simultaneous treatment of continuous and discrete systems and of all notions of stability, called T-stability. We investigate stabilizing control design by output feedback of input/output (IO) behaviors and study the full feedback IO behavior, especially its autonomous part and not only its transfer matrix. (2) The new technique is characterized by the permanent application of the injective cogenerator quotient signal module [Formula: see text] and of quotient behaviors [Formula: see text] of [Formula: see text]-behaviors B. (3) For the control tasks of tracking, disturbance rejection, model matching, and decoupling and not necessarily proper plants we derive necessary and sufficient conditions for the existence of proper stabilizing compensators with proper and stable closed loop behaviors, parametrize all such compensators as IO behaviors and not only their transfer matrices and give new algorithms for their construction. Moreover we solve the problem of pole placement or spectral assignability for the complete feedback behavior. The properness of the full feedback behavior

  6. The Measurable Effects of Germanium Loaded into the Pusher of a Pushered Single Shell Capsule Designed for the National Ignition Facility

    Science.gov (United States)

    Tipton, Robert; Baker, Kevin; Casey, Daniel; Dewald, Eduard; Graziani, Frank; MacLaren, Steve; Nikroo, Abass; Pino, Jesse; Ralph, Joe; Remington, Bruce; Sacks, Ryan; Salmonson, Jay; Smalyuk, Vladimir

    2016-10-01

    Germanium loaded pushered single shells (PSS) have been designed as a vehicle to study the effects of turbulent mixing between the DT fuel and a pusher which is not fully ionized. This is intended as a surrogate for the high-Z mixing expected in future double-shell ignition capsules. These PSS experiments will be diagnosed by loading deuterium along with the germanium into the GDP pusher and filling the capsule with a mixture of tritium and hydrogen. In such CD mix experiments, the measured number of DT neutrons along with the inferred ion temperature from the time-of-flight thermal broadening provides detailed information about the annular mixing of the fuel and the pusher. This paper will compare the expected DT mix signals from capsules loaded with germanium to control capsules fired without any germanium. Leading turbulent mix models predict the germanium loaded capsules and no-germanium control capsules will produce significantly different results. This work was performed under the auspices of the U.S. Department of Energy by LLNL under contract DE-AC52-07NA27344,LLNS, LLC.

  7. Enabling Parametric Optimal Ascent Trajectory Modeling During Early Phases of Design

    Science.gov (United States)

    Holt, James B.; Dees, Patrick D.; Diaz, Manuel J.

    2015-01-01

    -modal due to the interaction of various constraints. Additionally, when these obstacles are coupled with The Program to Optimize Simulated Trajectories [1] (POST), an industry standard program to optimize ascent trajectories that is difficult to use, it requires expert trajectory analysts to effectively optimize a vehicle's ascent trajectory. As it has been pointed out, the paradigm of trajectory optimization is still a very manual one because using modern computational resources on POST is still a challenging problem. The nuances and difficulties involved in correctly utilizing, and therefore automating, the program presents a large problem. In order to address these issues, the authors will discuss a methodology that has been developed. The methodology is two-fold: first, a set of heuristics will be introduced and discussed that were captured while working with expert analysts to replicate the current state-of-the-art; secondly, leveraging the power of modern computing to evaluate multiple trajectories simultaneously, and therefore, enable the exploration of the trajectory's design space early during the pre-conceptual and conceptual phases of design. When this methodology is coupled with design of experiments in order to train surrogate models, the authors were able to visualize the trajectory design space, enabling parametric optimal ascent trajectory information to be introduced with other pre-conceptual and conceptual design tools. The potential impact of this methodology's success would be a fully automated POST evaluation suite for the purpose of conceptual and preliminary design trade studies. This will enable engineers to characterize the ascent trajectory's sensitivity to design changes in an arbitrary number of dimensions and for finding settings for trajectory specific variables, which result in optimal performance for a "dialed-in" launch vehicle design. The effort described in this paper was developed for the Advanced Concepts Office [2] at NASA Marshall

  8. Parametric Optimization of Some Critical Operating System Functions--An Alternative Approach to the Study of Operating Systems Design

    Science.gov (United States)

    Sobh, Tarek M.; Tibrewal, Abhilasha

    2006-01-01

    Operating systems theory primarily concentrates on the optimal use of computing resources. This paper presents an alternative approach to teaching and studying operating systems design and concepts by way of parametrically optimizing critical operating system functions. Detailed examples of two critical operating systems functions using the…

  9. Development and utilization of irradiational capsule - Mechanical and thermal performance analysis and development of design program on the cylindrical structures with multi-holes

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young Shin; Choi, M. H.; Shin, D. S. [Chungnam National University, Taejon (Korea)

    2000-04-01

    Irradiation tests in the research reactor are used with the specially designed capsules for irradiation test and loop. Accordingly, suitable instrumented capsule for HANARO must be designed and manufactured. To satisfy the requirements of users and to conduct irradiation test effectively, the accurate informations on the thermal and mechanical characteristics of capsule should be understood. The structural analysis results show that stress characteristics of the cylinder with multi-holes is not significantly effected by the sizes of specimen hole, numbers of specimen and eccentric characteristics. The thermal and structural analysis of the capsule with multi-holes under thermal loading shows that the peak temperature in the circular cylinder is occurred in the specimens inserted in the center or specimen holes and is significantly effected by gap size between the holder and the external tube. In this study, CAPSYS program is developed by interfacing finite element analysis program, ANSYS with graphic user interface program, VISUAL C++. This program will be useful on the design and safety analysis of the capsule for material irradiation test. 20 refs., 37 figs., 9 tabs. (Author)

  10. Parametric analysis and design equation of ultimate capacity for unstiffened overlapped CHS K-joints

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A finite element model simulating an experiment on unstiffened,overlapped circular hollow structure (CHS)K-joints was generated and validated by comparing the ultimate capacities,deformation processes and failure modes of the experimental results.Using this model,the stress distribution,propagation of plasticity and the failure modes of overlapped joints with through-brace-in-compression and welded hidden seams were analyzed.The effect of geometric parameters,with or without hidden welds,and the loading hierarchy reversal of braces on the ultimate capacity of the joints were also studied.The results of finite element parametric analysis indicate that the brace-tochord thickness ratio has relatively large effects on the failure mechanism and ultimate capacity of overlapped joints.It was also found that the absence of hidden welds has less significance on the ultimate capacity of through-brace-incompression joints than through-brace-in tension joints.Finally,based on the design equation of gap joints,a formula predicting the ultimate capacity of overlapped CHS K-joints was derived by applying multivariate regression analysis.Results from the proposed design equation are consistent with experimental results.

  11. Design of vibratory energy harvesters under stochastic parametric uncertainty: a new optimization philosophy

    Science.gov (United States)

    Haji Hosseinloo, Ashkan; Turitsyn, Konstantin

    2016-05-01

    Vibratory energy harvesters as potential replacements for conventional batteries are not as robust as batteries. Their performance can drastically deteriorate in the presence of uncertainty in their parameters. Parametric uncertainty is inevitable with any physical device mainly due to manufacturing tolerances, defects, and environmental effects such as temperature and humidity. Hence, uncertainty propagation analysis and optimization under uncertainty seem indispensable with any energy harvester design. Here we propose a new modeling philosophy for optimization under uncertainty; optimization for the worst-case scenario (minimum power) rather than for the ensemble expectation of the power. The proposed optimization philosophy is practically very useful when there is a minimum requirement on the harvested power. We formulate the problems of uncertainty propagation and optimization under uncertainty in a generic and architecture-independent fashion, and then apply them to a single-degree-of-freedom linear piezoelectric energy harvester with uncertainty in its different parameters. The simulation results show that there is a significant improvement in the worst-case power of the designed harvester compared to that of a naively optimized (deterministically optimized) harvester. For instance, for a 10% uncertainty in the natural frequency of the harvester (in terms of its standard deviation) this improvement is about 570%.

  12. Adaptive Sliding Mode Control Design of a SCARA Robot Manipulator System Under Parametric Variations

    Directory of Open Access Journals (Sweden)

    F. Adelhed

    2015-12-01

    Full Text Available – The sliding mode control (SMC has yet proven its efficiency through several theoretical researches. Indeed, the robotic field is recognized as one of the main SMC portals on practical implementations. The interest of this work consists in testing the SMC robustness and its reliability versus the parameters variation and model uncertainties. In this paper, an algorithm for trajectory tracking task of robot manipulators based on a SMC has been proposed. Then, aiming to deal with the presence of disturbances and parametric modeling uncertainties, the adopted control law has been extended to an adaptive SMC version based integral sliding surface, where the selection of the parameters adaptation law has been detailed. It has been proven that the adaptive control design can stabilize both position and velocity of the system, where the explicit use of the system dynamic model becomes no longer required. Simulation results performed on a SCARA robot manipulator reveal improving control acting clearly denoted by the introduction of the adaptive control design

  13. Summary Report for Capsule Dry Storage Project

    Energy Technology Data Exchange (ETDEWEB)

    JOSEPHSON, W S

    2003-09-04

    There are 1.936 cesium (Cs) and strontium (Sr) capsules stored in pools at the Waste Encapsulation and Storage Facility (WESF). These capsules will be moved to dry storage on the Hanford Site as an interim measure to reduce risk. The Cs/Sr Capsule Dry Storage Project (CDSP) is conducted under the assumption the capsules will eventually be moved to the repository at Yucca Mountain, and the design criteria include requirements that will facilitate acceptance at the repository. The storage system must also permit retrieval of capsules in the event vitrification of the capsule contents is pursued. A cut away drawing of a typical cesium chloride (CsCI) capsule and the capsule property and geometry information are provided in Figure 1.1. Strontium fluoride (SrF{sub 2}) capsules are similar in design to CsCl capsules. Further details of capsule design, current state, and reference information are given later in this report and its references. Capsule production and life history is covered in WMP-16938, Capsule Characterization Report for Capsule Dry Storage Project, and is briefly summarized in Section 5.2 of this report.

  14. Design of triply-resonant microphotonic parametric oscillators based on Kerr nonlinearity.

    Science.gov (United States)

    Zeng, Xiaoge; Popović, Miloš A

    2014-06-30

    We propose optimal designs for triply-resonant optical parametric oscillators (OPOs) based on degenerate four-wave mixing (FWM) in microcavities. We show that optimal designs in general call for different external coupling to pump and signal/idler resonances. We provide a number of normalized performance metrics including threshold pump power and maximum achievable conversion efficiency for OPOs with and without two-photon (TPA) and free-carrier absorption (FCA). We find that the maximum achievable conversion efficiency is bound to an upper limit by nonlinear and free-carrier losses independent of pump power, while linear losses only increase the pump power required to achieve a certain conversion efficiency. The results of this work suggest unique advantages in on-chip implementations that allow explicit engineering of resonances, mode field overlaps, dispersion, and wavelength-and mode-selective coupling. We provide universal design curves that yield optimum designs, and give example designs of microring-resonator-based OPOs in silicon at the wavelengths 1.55 μm (with TPA) and 2.3 μm (no TPA) as well as in silicon nitride (Si(3)N(4)) at 1.55 μm. For typical microcavity quality factor of 10(6), we show that the oscillation threshold in excitation bus can be well into the sub-mW regime for silicon microrings and a few mW for silicon nitride microrings. The conversion efficiency can be a few percent when pumped at 10 times of the threshold. Next, based on our results, we suggest a family of synthetic "photonic molecule"-like, coupled-cavity systems to implement optimum FWM, where structure design for control of resonant wavelengths can be separated from that of optimizing nonlinear conversion efficiency, and where furthermore pump, signal, and idler coupling to bus waveguides can be controlled independently, using interferometric cavity supermode coupling as an example. Finally, consideration of these complex geometries calls for a generalization of the nonlinear

  15. Toward better understanding of powder avalanching and shear cell parameters of drug-excipient blends to design minimal weight variability into pharmaceutical capsules.

    Science.gov (United States)

    Nalluri, Venkateshwar Rao; Puchkov, Maxim; Kuentz, Martin

    2013-02-14

    Powder flow of mixtures is complex and not properly understood. The selection of drug-excipient blends with inadequate powder flow can lead to quality issues of the final dosage form. Therefore, this work aims at a better understanding of how changes in powder flow of binary blends can lead to weight variability in pharmaceutical capsule filling. We used image-analysis-based powder avalanching and shear cell testing to study blends of paracetamol and microcrystalline cellulose. A pilot-scale machine with dosator principle was employed for encapsulation. As a result, the powder flow properties improved generally with rising amounts of microcrystalline cellulose. However, a negative correlation was observed between avalanche angle and angle of internal friction. Results were discussed and percolation theory was considered to explain abrupt changes in the observed flow properties. This was particularly helpful for analysis of the capsule-filling data, since capsule weight variability displayed a threshold behavior as a function of the mixture fraction. The capsule weight variability correlated with the angle of internal friction as well as with the angle and the energy of avalanches. Based on the results we proposed a strategy of how to design minimal weight variability into powder-filled capsules.

  16. Parametric design of silo steel framework of concrete mixing station based on the finite element method and MATLAB

    OpenAIRE

    Long Hui; Huang Changzheng; Li Jing; Liu Feng

    2016-01-01

    When the structure of the silo steel framework of concrete mixing station is designed, In most cases, the dimension parameters, shape parameters and position parameters of silo steel framework beams are changed as the productivity adjustment of the concrete mixing station, but the structure types of silo steel framework will remain the same. In order to acquire strength of silo steel framework rapidly and efficiently, it is need to provide specialized parametric strength computational softwar...

  17. Design of Raman-parametric fiber amplifier for wavelength division multiplex transmission system

    Institute of Scientific and Technical Information of China (English)

    Xiaohong Jiang; Chun Jiang; Xiaoming Zhang

    2008-01-01

    We optimize the novel configuration of a hybrid fiber amplifier-Raman assisted-fiber-based optical parametric amplifier (R-FOPA), in which the parametric gain and Raman gain profiles are combined to achieve a flat composite gain profile.The pump powers and the fiber length in the hybrid amplifier are effectively optimized by genetic algorithm (GA) scheme.The optimization results indicate that the R-FOPA can achieve a 200-nm flat bandwidth spectrum with the gain of 20 dB and ripple of less than 4 dB.

  18. A new design methodology of obtaining wide band high gain broadband parametric source for infrared wavelength applications

    Science.gov (United States)

    Maji, Partha Sona; Roy Chaudhuri, Partha

    2016-03-01

    In this article, we have presented a new design methodology of obtaining wide band parametric sources based on highly nonlinear chalcogenide material of As2S3. The dispersion profile of the photonic crystal fiber (PCF) has been engineered wisely by reducing the diameter of the second air-hole ring to have a favorable higher order dispersion parameter. The parametric gain dependence upon fiber length, pump power, and different pumping wavelengths has been investigated in detail. Based upon the nonlinear four wave mixing phenomenon, we are able to achieve a wideband parametric amplifier with peak gain of 29 dB with FWHM of ≈2000 nm around the IR wavelength by proper tailoring of the dispersion profile of the PCF with a continuous wave Erbium (Er3+)-doped ZBLAN fiber laser emitting at 2.8 μm as the pump source with an average power of 5 W. The new design methodology will unleash a new dimension to the chalcogenide material based investigation for wavelength translation around IR wavelength band.

  19. 带式输送机托辊的参数化设计%Parametric design on belt conveyor roller

    Institute of Scientific and Technical Information of China (English)

    冷岳峰

    2013-01-01

    To solve parametric drawing problem of belt conveyor roller design,uses inlays language VBA principle and method to achieves the parametric design process of the belt conveyor roller components. uses inlays language VBA to writing drawing program,using this application,designers can input the corresponding parameters to get the result of roller drawing to get belt conveyor roller drawings and assembly drawings and other drawing results.The parametric design method reducts design cycle to some kinds of components, reduce the designer’s drawing labour intensity ,and enhances the drawing quality and efficiency.%  为解决带式输送机托辊设计中的参数化绘图问题,采用 VBA 对带式输送机托辊进行参数化设计的原理和方法,实现在 AutoCAD2004环境下,利用 AutoCAD 自带的二次开发软件包 VBA 编制绘图程序,利用此应用程序,设计人员只需输入几个相应的设计参数就可得到托辊完整的零件图和装配图等绘图结果。这种参数化设计方法不仅缩短了对某类零件的设计周期,减轻设计人员绘图劳动强度,同时还提高设计的质量和效率。

  20. Parametric and Generative Design Techniques for Digitalization in Building Industry: the Case Study of Glued- Laminated-Timber Industry

    Science.gov (United States)

    Pasetti Monizza, G.; Matt, D. T.; Benedetti, C.

    2016-11-01

    According to Wortmann classification, the Building Industry (BI) can be defined as engineer-to-order (ETO) industry: the engineering-process starts only when an order is acquired. This definition implies that every final product (building) is almost unique’ and processes cannot be easily standardized or automated. Because of this, BI is one of the less efficient industries today’ mostly leaded by craftsmanship. In the last years’ several improvements in process efficiency have been made focusing on manufacturing and installation processes only. In order to improve the efficiency of design and engineering processes as well, the scientific community agrees that the most fruitful strategy should be Front-End Design (FED). Nevertheless, effective techniques and tools are missing. This paper discusses outcomes of a research activity that aims at highlighting whether Parametric and Generative Design techniques allow reducing wastes of resources and improving the overall efficiency of the BI, by pushing the Digitalization of design and engineering processes of products. Focusing on the Glued-Laminated-Timber industry, authors will show how Parametric and Generative Design techniques can be introduced in a standard supply-chain system, highlighting potentials and criticism on the supply-chain system as a whole.

  1. Parametric design of silo steel framework of concrete mixing station based on the finite element method and MATLAB

    Directory of Open Access Journals (Sweden)

    Long Hui

    2016-01-01

    Full Text Available When the structure of the silo steel framework of concrete mixing station is designed, In most cases, the dimension parameters, shape parameters and position parameters of silo steel framework beams are changed as the productivity adjustment of the concrete mixing station, but the structure types of silo steel framework will remain the same. In order to acquire strength of silo steel framework rapidly and efficiently, it is need to provide specialized parametric strength computational software for engineering staff who does not understand the three-dimensional software such as PROE and finite element analysis software. By the finite element methods(FEM, the parametric stress calculation modal of the silo steel framework of concrete mixing station is established, which includes dimension parameters, shape parameters, position parameters and applied load parameters of each beams, and then the parametric calculation program is written with MATLAB. The stress equations reflect the internal relationship between the stress of the silo steel frames with the dimension parameters, shape parameters, position parameters and load parameters. Finally, an example is presented, the calculation results show the stress of all members and the size and location of the maximum stress, which agrees well with realistic cases.

  2. Geometric Continuity: A Parametrization Independent Measure of Continuity for Computer Aided Geometric Design

    Science.gov (United States)

    1985-08-01

    Proceedings, ACM, San Francisco, (July, 1985). 57. Michael Spivak , Calculus on Manifolds, W. A. Benjamin, Inc., New York (1965). 58. Michael Spivak , A... Calculus 6.4. Elementary Manifold Theory 6.4.1. Orientable Manifolds . 6.4.2. Maps on Manifolds 6.5. Abstract Splines . . . . 6.6. Parametric Splines...with multivariate calculus may recognize equation (2.30) as the Jacobian of the change of variables (see Section 6.3). 2. AN INTUITIVE APPROACH 31

  3. Parametric study of variation in cargo-airplane performance related to progression from current to spanloader designs

    Science.gov (United States)

    Toll, T. A.

    1980-01-01

    A parametric analysis was made to investigate the relationship between current cargo airplanes and possible future designs that may differ greatly in both size and configuration. The method makes use of empirical scaling laws developed from statistical studies of data from current and advanced airplanes and, in addition, accounts for payload density, effects of span distributed load, and variations in tail area ratio. The method is believed to be particularly useful for exploratory studies of design and technology options for large airplanes. The analysis predicts somewhat more favorable variations of the ratios of payload to gross weight and block fuel to payload as the airplane size is increased than has been generally understood from interpretations of the cube-square law. In terms of these same ratios, large all wing (spanloader) designs show an advantage over wing-fuselage designs.

  4. Analysis and design of a capsule landing system and surface vehicle control system for Mars exploration

    Science.gov (United States)

    Gisser, D. G.; Frederick, D. K.; Lashmet, P. K.; Sandor, G. N.; Shen, C. N.; Yerazunis, S. Y.

    1975-01-01

    Problems related to an unmanned exploration of the planet Mars by means of an autonomous roving planetary vehicle are investigated. These problems include: design, construction and evaluation of the vehicle itself and its control and operating systems. More specifically, vehicle configuration, dynamics, control, propulsion, hazard detection systems, terrain sensing and modelling, obstacle detection concepts, path selection, decision-making systems, and chemical analyses of samples are studied. Emphasis is placed on development of a vehicle capable of gathering specimens and data for an Augmented Viking Mission or to provide the basis for a Sample Return Mission.

  5. Capsule endoscopy

    Institute of Scientific and Technical Information of China (English)

    Miguel Mu(n)oz-Navas

    2009-01-01

    Capsule endoscopy (CE) is a simple, safe, non-invasive, reliable technique, well accepted and tolerated by the patients, which allows complete exploration of the small intestine. The advent of CE in 2000 has dramatically changed the diagnosis and management of many diseases of the small intestine, such as obscure gastrointestinal bleeding, Crohn's disease, small bowel tumors, polyposis syndromes, etc. CE has become the gold standard for the diagnosis of most diseases of the small bowel. Lately this technique has also been used for esophageal and colonic diseases.

  6. Investigation of Multi-Input Multi-Output Robust Control Methods to Handle Parametric Uncertainties in Autopilot Design.

    Science.gov (United States)

    Kasnakoğlu, Coşku

    2016-01-01

    Some level of uncertainty is unavoidable in acquiring the mass, geometry parameters and stability derivatives of an aerial vehicle. In certain instances tiny perturbations of these could potentially cause considerable variations in flight characteristics. This research considers the impact of varying these parameters altogether. This is a generalization of examining the effects of particular parameters on selected modes present in existing literature. Conventional autopilot designs commonly assume that each flight channel is independent and develop single-input single-output (SISO) controllers for every one, that are utilized in parallel for actual flight. It is demonstrated that an attitude controller built like this can function flawlessly on separate nominal cases, but can become unstable with a perturbation no more than 2%. Two robust multi-input multi-output (MIMO) design strategies, specifically loop-shaping and μ-synthesis are outlined as potential substitutes and are observed to handle large parametric changes of 30% while preserving decent performance. Duplicating the loop-shaping procedure for the outer loop, a complete flight control system is formed. It is confirmed through software-in-the-loop (SIL) verifications utilizing blade element theory (BET) that the autopilot is capable of navigation and landing exposed to high parametric variations and powerful winds.

  7. Osmotically regulated floating asymmetric membrane capsule for controlled site-specific delivery of ranitidine hydrochloride: optimization by central composite design.

    Science.gov (United States)

    Chauhan, Manvendra S; Kumar, Anil; Pathak, Kamla

    2012-12-01

    A nondisintegrating, floating asymmetric membrane capsule (FAMC) was developed to achieve site-specific osmotic flow of a highly water-soluble drug, ranitidine hydrochloride (RHCl), in a controlled manner. Solubility suppression of RHCl was achieved by the common ion effect, using optimized coated sodium chloride as a formulation component. The capsular wall of FAMC was prepared by the phase inversion process wherein the polymeric membrane was precipitated on glass pins by dipping them in a solution of cellulose acetate followed by quenching. Central composite design was utilized to investigate the influence of independent variables, namely, level(s) of membrane former, pore former, and osmogen, on percent cumulative drug release (response). The release mechanism of RHCl through FAMC was confirmed as osmotic pumping. The asymmetry of the membrane was characterized by scanning electron microscopy that revealed a dense nonporous outer region of membrane supported by an inner porous region. Differential scanning calorimetry indicated no incompatibility between the drug and excipients. In vitro drug release in three biorelevant media, pH 2.5 (low fed), pH 4.5 (intermediate fed), and pH 6.5 (high fed), demonstrated pH-independent release of RHCl (P > 0.05). Floating ability for 12 h of the optimized FAMC9 was visually examined during the in vitro release studies that showed maximal drug release with zero-order kinetics (r (2) = 0.9991). Thus, a novel osmotically regulated floating capsular system was developed for site-specific delivery of RHCl.

  8. Design of Luenberger function observer with disturbance decoupling for matrix second-order linear systems-a parametric approach

    Institute of Scientific and Technical Information of China (English)

    Wu Yunli; Duan Guangren

    2006-01-01

    A simple method for disturbance decoupling for matrix second-order linear systems is proposed directly in matrix second-order framework via Luenberger function observers based on complete parametric eigenstructure assignment.By introducing the H2 norm of the transfer function from disturbance to estimation error, sufficient and necessary conditions for disturbance decoupling in matrix second-order linear systems are established and are arranged into constraints on the design parameters via Luenberger function observers in terms of the closed-loop eigenvalues and the group of design parameters provided by the eigenstructure assignment approach. Therefore, the disturbance decoupling problem is converted into an eigenstructure assignment problem with extra parameter constraints. A simple example is investigated to show the effect and simplicity of the approach.

  9. Variable Sweep Transition Flight Experiment (VSTFE)-Parametric Pressure Distribution Boundary Layer Stability Study and Wing Glove Design Task

    Science.gov (United States)

    Rozendaal, Rodger A.

    1986-01-01

    The Variable Sweep Transition Flight Experiment (VSTFE) was initiated to establish a boundary-layer transition data base for laminar flow wing design. For this experiment, full-span upper-surface gloves will be fitted to a variable sweep F-14 aircraft. The results of two initial tasks are documented: a parametric pressure distribution/boundary-layer stability study and the design of an upper-surface glove for Mach 0.8. The first task was conducted to provide a data base from which wing-glove pressure distributions could be selected for glove designs. Boundary-layer stability analyses were conducted on a set of pressure distributions for various wing sweep angles, Mach numbers, and Reynolds number in the range of those anticipated for the flight-test program. The design procedure for the Mach 0.8 glove is described, and boundary-layer stability calculations and pressure distributions are presented both at design and off-design conditions. Also included is the analysis of the clean-up glove (smoothed basic wing) that will be flight-tested initially and the analysis of a Mach 0.7 glove designed at the NASA Langley Research Center.

  10. Parametric Design of Chain Based on Pro/E%基于Pro/E的链条参数化设计

    Institute of Scientific and Technical Information of China (English)

    于文菡; 蹇兴东; 史庆春; 孙江艳

    2011-01-01

    阐述了使用Pro/E参数化设计链条的方法.巧妙地运用了尺寸阵列命令,选择好阵列方法和定义好阵列驱动尺寸,快速准确地生成特征,并使用现代的设计方法,对参数进行优化设计.在链条的设计中实现优化设计目标,解决了阵列后出现的一些问题,提高了设计效率和设计质量.最后设计链节零件,完成装配,获得了完整的链条造型.%It expounds the method of using parametric to design chain based on Pro/E, cleverly use size array orders Choose array method and defined the array driven dimensions, quickly and accurately formation characteristics, and use modern design method, generated characteristic parameter optimization in the design of chain, reach optimization design goal, solve the problems appeared after array, improved the design efficiency and quality of design. At last, design chain section parts and complete assembly, obtain a complete chain model.

  11. Diseño paramétrico de pinzas de fricción // Parametric Design a Gripper.

    Directory of Open Access Journals (Sweden)

    S. A. Marrero-Osorio

    2009-01-01

    Full Text Available En el trabajo se expone una forma de realizar el diseño depurado de máquinas mediante el empleode la tecnología paramétrica. Para resolver el problema de diseño se utiliza un modelo deingeniería que abarca geometría, materiales, cargas, resistencia, tecnología y aspectos económicosentre otros. Con el mismo fin se hace uso del método de los grafos dicromáticos, que facilitaconsiderablemente el manejo del modelo matemático, el planteamiento del problema de diseño,su caracterización y su resolución. Todo se ejemplifica a través de una máquina relativamentesencilla: una pinza de fricción utilizable en la manipulación de losas prefabricadas.Palabras claves: diseño paramétrico, modelo matemático, grafos dicromáticos, pinzas manipuladoras,prefabricado.____________________________________________________________________________AbstractIn this paper a way of making a detailed design of machines by the use of Parametric Technology isexposed. To solve the design task, an engineering model that covers geometry, materials, loads,stresses, manufacture, economy and other aspects is used. With the same objective theDichromatic Graphs Method is used, which considerably facilitates the mathematical model'shandling, the definition of the design problem, and its characterization and solution. An example ofdesign in a relative easy machine illustrates the process: a friction gripper used in the manipulationof light prefabricated elements.Key words: parametric design, mathematical model, Dichromatic Graphs, fristion grippers, prefabricatedelements.

  12. Optomechanical design and construction of a vacuum-compatible optical parametric oscillator for generation of squeezed light.

    Science.gov (United States)

    Wade, A R; Mansell, G L; McRae, T G; Chua, S S Y; Yap, M J; Ward, R L; Slagmolen, B J J; Shaddock, D A; McClelland, D E

    2016-06-01

    With the recent detection of gravitational waves, non-classical light sources are likely to become an essential element of future detectors engaged in gravitational wave astronomy and cosmology. Operating a squeezed light source under high vacuum has the advantages of reducing optical losses and phase noise compared to techniques where the squeezed light is introduced from outside the vacuum. This will ultimately provide enhanced sensitivity for modern interferometric gravitational wave detectors that will soon become limited by quantum noise across much of the detection bandwidth. Here we describe the optomechanical design choices and construction techniques of a near monolithic glass optical parametric oscillator that has been operated under a vacuum of 10(-6) mbar. The optical parametric oscillator described here has been shown to produce 8.6 dB of quadrature squeezed light in the audio frequency band down to 10 Hz. This performance has been maintained for periods of around an hour and the system has been under vacuum continuously for several months without a degradation of this performance.

  13. Performance evaluation and parametric optimum design of a vacuum thermionic solar cell

    Energy Technology Data Exchange (ETDEWEB)

    Liao, Tianjun; Chen, Xiaohang, E-mail: chenxh@xmu.edu.cn; Chen, Jincan [Fujian Key Laboratory of Semiconductor Materials and Applications and Department of Physics, Xiamen University, Xiamen 361005 (China); Lin, Bihong [College of Information Science and Engineering, Huaqiao University, Xiamen 361021 (China)

    2016-01-18

    A model of the vacuum thermionic solar cell (VTSC) consisting of a solar concentrator, an emitter, and a collector is proposed, in which the various heat losses including the far- and near-field thermal radiation are taken into account. Formula for the overall efficiency of the system is analytically derived. For given values of the ratio of the front surface area of the absorber to that of the emitter and the vacuum gap between the emitter and the collector, the operating temperatures of the emitter and collector are determined by solving the energy balance equations. The maximum efficiency of the VTSC are calculated for given values of the work functions of the emitter and collector materials, and some key parameters such as the net current density of the VTSC, operating temperatures of the emitter and collector, vacuum gap between the emitter and the collector, and area ratio of the absorber to the emitter are optimally determined. Furthermore, the effects of the work functions and the concentration ratio of the solar irradiation on the performance of the VTSC are discussed and several parametric selection criteria are obtained.

  14. Parametric design-based modal damped vibrational piezoelectric energy harvesters with arbitrary proof mass offset: Numerical and analytical validations

    Science.gov (United States)

    Lumentut, Mikail F.; Howard, Ian M.

    2016-02-01

    This paper focuses on the primary development of novel numerical and analytical techniques of the modal damped vibration energy harvesters with arbitrary proof mass offset. The key equations of electromechanical finite element discretisation using the extended Lagrangian principle are revealed and simplified to give matrix and scalar forms of the coupled system equations, indicating the most relevant numerical technique for the power harvester research. To evaluate the performance of the numerical study, the analytical closed-form boundary value equations have been developed using the extended Hamiltonian principle. The results from the electromechanical frequency response functions (EFRFs) derived from two theoretical studies show excellent agreement with experimental studies. The benefit of the numerical technique is in providing effective and quick predictions for analysing parametric designs and physical properties of piezoelectric materials. Although analytical technique provides a challenging process for analysing the complex smart structure, it shows complementary study for validating the numerical technique.

  15. Estrategia para el diseño paramétrico basado en modelos. // Strategy for model-based parametric design.

    Directory of Open Access Journals (Sweden)

    S. A. Marrero Osorio

    2008-09-01

    Full Text Available El presente artículo expone una manera de diseñar paramétricamente utilizando los programas de computadora (CAD,CAE, PMS difundidos entre los diseñadores durante los últimos 20 años. La propuesta se basa en modelos matemáticosque consideran el conocimiento sobre la ingeniería del objeto de diseño y lo relacionado con la confección de su modelovirtual tridimensional, planos y otro aspectos; utilizando el Método de los Grafos Dicromáticos para resolver los problemascomputacionales que se presentan en el diseño paramétrico. Se analizan los puntos de vista de diferentes autores en relacióncon el proceso general de diseño y es ubicado dentro del mismo el diseño paramétrico, realizándose una explicación formalque permite arribar a conclusiones interesantes.Palabras claves: Diseño paramétrico, diseño asistido por computadoras (CAD, ingeniería asistida porcomputadoras (CAE, software para el modelado paramétrico (PMS, resolución de problemas._____________________________________________________________________________Abstract:The present article exposes a way to design parametrically applying programs (CAD, CAE, PMS accepted by designers along thelast 20 years. The proposal is based on mathematical models that ponder the knowledge on the engineering of the design object andthe building of its three-dimensional virtual models, blueprints and another aspects; using the dichromatic graph method to solvecomputational problems in parametric design. The points of view of different authors are analyzed in connection with the generalprocess of design, locating parametric design inside it, carrying out a formal explanation which arrives to interesting conclusions.Key words: Parametric design, computer aided design (CAD, computer aided engineering (CAE,parametric modeling software (PMS, problem solving.

  16. Integration of capturing design intent and parametric design%设计意图捕捉与参数化设计集成研究

    Institute of Scientific and Technical Information of China (English)

    姜少飞; 陈帅; 鲁聪达; 黄敬猛

    2011-01-01

    为实现意图捕捉、建模和求解,并且使求解结果可直接作为参数化设计的输入,提出了意图域、载体域和信息域三个概念.从需求的角度分解设计意图,形成意图域;在意图域的指导下,对产品进行结构划分,形成载体域.用意图域映射载体域,形成含有设计信息的信息域.信息域中每个信息单元为一个独立的物理模型,应用优化理论求解模型,得到参数化设计中的主参数.以叉车设计过程为例验证了所提方法的有效性.%In order to capture, model and solve design intent, three domain including intent domain, construction domain and information domain were proposed.The solution to design intent was taken as the input of parametric design system.Intent domain was obtained via decomposing design intent from the perspective of demand, according to its instructions, construction domain was generated by decomposing the structure of product.Then, information domain was produced by mapping the intent domain to the construction domain。 The information domain was a kind of physical structure with design information.Each unit in information domain was an independent physical model.It was solved by optimization method and the main parameter in parametric design was obtained.Finally, the forklift design process validated the effectiveness of this method.

  17. Parametric Resonance in Dynamical Systems

    CERN Document Server

    Nijmeijer, Henk

    2012-01-01

    Parametric Resonance in Dynamical Systems discusses the phenomenon of parametric resonance and its occurrence in mechanical systems,vehicles, motorcycles, aircraft and marine craft, and micro-electro-mechanical systems. The contributors provide an introduction to the root causes of this phenomenon and its mathematical equivalent, the Mathieu-Hill equation. Also included is a discussion of how parametric resonance occurs on ships and offshore systems and its frequency in mechanical and electrical systems. This book also: Presents the theory and principles behind parametric resonance Provides a unique collection of the different fields where parametric resonance appears including ships and offshore structures, automotive vehicles and mechanical systems Discusses ways to combat, cope with and prevent parametric resonance including passive design measures and active control methods Parametric Resonance in Dynamical Systems is ideal for researchers and mechanical engineers working in application fields such as MEM...

  18. Parametric Fuselage Geometry Generation and Aerodynamic Performance Prediction in Preliminary Rotorcraft Design

    OpenAIRE

    Kunze, Philipp

    2013-01-01

    The creation of an integrated rotorcraft conceptual and preliminary design framework at DLR involved the development of geometry and fuselage aerodynamics modules at the Institute of Aerodynamics and Flow Technology. After a short revision of the RIDE rotorcraft design environment architecture this paper focuses on the implementation of these disciplinary modules. The aim of the geometry module is to bridge the gap between conceptual and preliminary design and to allow for geometry parameter ...

  19. A parametric physics based creep life prediction approach to gas turbine blade conceptual design

    Science.gov (United States)

    Smith, Marcus Edward Brockbank

    The required useful service lives of gas turbine components and parts are naturally one of the major design constraints limiting the gas turbine design space. For example, the required service life of a turbine blade limits the firing temperature in the combustor, which in turn limits the performance of the gas turbine. For a cooled turbine blade, it also determines the necessary cooling flow, which has a strong impact on the turbine efficiency. In most gas turbine design practices, the life prediction is only emphasized during or after the detailed design has been completed. Limited life prediction efforts have been made in the early design stages, but these efforts capture only a few of the necessary key factors, such as centrifugal stress. Furthermore, the early stage prediction methods are usually hard coded in the gas turbine system design tools and hidden from the system designer's view. The common failure mechanisms affecting the service life, such as creep, fatigue and oxidation, are highly sensitive to the material temperatures and/or stresses. Calculation of these temperatures and stresses requires that the geometry, material properties, and operating conditions be known; information not typically available in early stages of design. Even without awareness of the errors, the resulting inaccuracy in the life prediction may mislead the system designers when examining a design space which is bounded indirectly by the inaccurate required life constraints. Furthermore, because intensive creep lifing analysis is possible only towards the end of the design process, any errors or changes will cost the engine manufacturer significant money; money that could be saved if more comprehensive creep lifing predictions were possible in the early stages of design. A rapid, physics-based life prediction method could address this problem by enabling the system designer to investigate the design space more thoroughly and accurately. Although not meant as a final decision

  20. Generative and Participatory Parametric Frameworks for Multi-Player Design Games

    NARCIS (Netherlands)

    Bier, H.; Ku, Y.

    2013-01-01

    Generative design processes have been the focus of current architectural research and practice largely due to the exploration of the phenomenon of emergence within self-organisation, generative grammars and evolutionary techniques. These techniques have been informing participatory urban design moda

  1. Stabilization of Parametric Roll Resonance with Active U-Tanks via Lyapunov Control Design

    DEFF Research Database (Denmark)

    Holden, Christian; Galeazzi, Roberto; Fossen, Thor Inge;

    2009-01-01

    design of an active u-tank stabilizer is carried out using Lyapunov theory. A nonlinear backstepping controller is developed to provide global exponential stability of roll. An extension of commonly used u-tank models is presented to account for large roll angles, and the control design is tested via...

  2. Experimental and Parametric Design of Petroleum Back-pressured Hydraulic Impactor

    Institute of Scientific and Technical Information of China (English)

    YUAN Guang-jie; YAO Zhen-qiang; CHEN Ping; HUANG Wan-zhi

    2005-01-01

    Percussive-rotary drilling technology was considered many years ago as one of the best approaches for hard rock drilling. It is a key for popularizing this technology on a large scale to design and make an impactor with excellent performance. This paper presents a suit of method to design the percussive parameters for the oil or gas field by introducing the working principle of back-pressured impactor, dividing the working periods of impactor into three phases and establishing the computer emulational model of percussive parameters. It draws a comparison between the results of model calculation and experiment on the basis of analyzing the experiment results of impactor.The conclude provides credible foundation for designing and further ameliorating the impactor.

  3. DESIGN AND PARAMETRIC OPTIMIZATION OF AN ORGANIC RANKINE CYCLE POWERED BY SOLAR ENERGY

    Directory of Open Access Journals (Sweden)

    Francesco Calise

    2013-01-01

    Full Text Available This study presents the simulation and performance analysis of a regenerative and superheated Organic Rankine Cycle (ORC. To this scope, anew simulation model has been developed. The model is based on zero-dimensional energy and mass balances for all the components of the system. Shell and tube heat expanders with single shell and double tube pass have been chosen. Pump and expander have been considered only form a thermodynamic point of view, with constant compressor and expansion efficiency. The simulations have been carried out in order to find different optimization criteria to use as preliminary design tools, especially for the organic fluid choice and the heat exchanger design. Firstly, the ORC performances have been evaluated for different organic medium, varying the temperature of the heat source. The global efficiency of the plant, the net electric power generation and the volumetric expansion ratio has been considered as evaluation parameters. The simulation results show that two hydrocarbons demonstrate good performance for low, medium and high heat source, namely Isobutene, n-Butene; R245fa can add to them for the exploitation of heat source up to 170°C. Additional simulations have been carried out to discover an optimization criterion for the heat exchanger design. The plant performances have been first evaluated varying one by one the following parameters: tube length, tube number and shell diameter. Then a global optimization was also performed using the Golden Search technique. The total cost of the plant has been considered as objective functions. With respect to the objective function, higher the boiling heat transfer area higher the electric power generation and the economical benefit. The optimal configuration, compared to the initial one, shows an increase of incomes and mechanical power equal to 60.1 and 48.2% respectively, against a decrease of global efficiency equal to 10.9%.

  4. Origami-inspired building block and parametric design for mechanical metamaterials

    Science.gov (United States)

    Jiang, Wei; Ma, Hua; Feng, Mingde; Yan, Leilei; Wang, Jiafu; Wang, Jun; Qu, Shaobo

    2016-08-01

    An origami-based building block of mechanical metamaterials is proposed and explained by introducing a mechanism model based on its geometry. According to our model, this origami mechanism supports response to uniaxial tension that depends on structure parameters. Hence, its mechanical properties can be tunable by adjusting the structure parameters. Experiments for poly lactic acid (PLA) samples were carried out, and the results are in good agreement with those of finite element analysis (FEA). This work may be useful for designing building blocks of mechanical metamaterials or other complex mechanical structures.

  5. Parametric analysis of the proton exchange membrane fuel cell performance using design of experiments

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Wei-Lung [School of Defense Science, Chung Cheng Institute of Technology, National Defense University, No. 190, Sanyuan 1st Street, Ta-Hsi, Taoyuan, Taiwan 335 (China); Wu, Sheng-Ju; Shiah, Sheau-Wen [Department of Power Vehicle and Systems Engineering, Chung Cheng Institute of Technology, National Defense University, No. 190, Sanyuan 1st Street, Ta-Hsi, Taoyuan, Taiwan 335 (China)

    2008-05-15

    Proton exchange membrane fuel cell (PEMFC) performance depends on different fuel cell operating temperatures, humidification temperatures, operating pressures, flow rates, and various combinations of these parameters. This study employed the method of the design of experiments (DOE) to obtain the optimal combination of the six primary operating parameters (fuel cell operating temperatures, operating pressures, anode and cathode humidification temperatures, anode and cathode stoichiometric flow ratios). In the first stage, this study adopted a 2{sup k-2} fractional factorial design of the DOE to determine whether these factors have significant effects on a response and the interactions between various parameters. Second, the L{sub 27}(3{sup 13}) orthogonal array of the Taguchi method is utilized to determine the optimal combination of factors for a fuel cell. Based on this study, the operating pressure, the operating temperature, and the interactions between operating temperature and operating pressure have a significant effect on the fuel cell performance. Among them, the operating pressure is the most important contributor. When the operating pressure increases, it should simultaneously lower the effects of other factors. While both the operating temperature and pressure increase simultaneously with that, the other factors are at appropriate conditions, it is possible to improve the fuel cell performance. (author)

  6. Parametric Design and Rapid Prototyping of Installation Box for Vehicle Terminal PCB

    Directory of Open Access Journals (Sweden)

    Wang Xingxing

    2016-01-01

    Full Text Available Installation box for vehicle terminal PCB (Printed Circuit Board was took as research object, which is encountered in the process of project developing. Vehicle terminal PCB in actual development process was set as an example, point cloud data were acquired by three coordinate measuring method; Imageware software was used to reconstruct the vehicle terminal PCB model, basic size parameters of vehicle terminal PCB can be got and then design parameters of installation box for vehicle terminal PCB can be determined. Design of the installation box for vehicle terminal PCB was completed based on Solidworks software, then 3D modeling and 2D drawing of installation box for vehicle terminal PCB was gained. Up Plus 2 rapid prototype machine was used to manufacture installation box for vehicle terminal PCB rapidly based on 3D printing technology, then prototype of installation box for vehicle terminal PCB was obtained. It is of certain engineering significant for single (small amount manufacturing of installation box for general PCB.

  7. Floating-roof steel tanks under harmonic settlement: FE parametric study and design criterion

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Large vertical steel tanks for fluid storage are usually constructed on soft foundations, so it is not surprising that the tank wall will settle unevenly with the settlement of the foundation, thus inducing deformations and stresses in the tank. This work investigates the linear static behavior of floating-roof tanks under harmonic settlement through finite element (FE) analyses. The influences of the radius-to-thickness ratio, the height-to-radius ratio and the wind girder stiffness on the structural behavior are first analyzed. Comparisons between the circumferential stresses in the wind girder and the vertical stresses in the tank bottom are then made. The displacement and the stress along the tank height are also discussed, and the concept of tank division along its height is presented. Finally, a design approximation for the radial displacement at the tank top is developed based on FE results, and a settlement criterion based on the top radial displacement is proposed which can be used in practical design.

  8. Shock Wave Observation in Narrow Tubes for a Parametric Study on Micro Wave Rotor Design

    Institute of Scientific and Technical Information of China (English)

    Koji Okamoto; Mikiya Araki

    2008-01-01

    Wave rotor is expected to improve the performance of micro gas turbines drastically. In the wave rotor design, the rotor speed is determined principally by the tube length. Therefore, a longer tube is preferable for miniaturized wave rotors to avoid the difficulty in bearings and lubrication system, while it may yield thicker wall boundary layer, shock wave dissipation and so on. In the present study, an experimental apparatus was built to visualize the wave rotor internal flow dynamics in a narrow tube by schlieren method and Laser Doppler Anemometry. In addition, different lengths of the tube were adopted and compared to investigate the effect of wall friction. Finally, 2D numerical simulation was performed and the results were compared with those of experiments.

  9. 离心泵叶轮的参数化设计%Parametric design of centrifugal pump impellers

    Institute of Scientific and Technical Information of China (English)

    张人会; 郑凯; 杨军虎; 李仁年

    2012-01-01

    The problems in the optimization design of centrifugal pump impeller were elaborated and it was found that the implicit relation between the hydraulic performance and the complicated geometry shape of impeller passages was a main obstacle. The existing parametric design methods for centrifugal pump impellers, such as the NURBS surface method, free-surface deformation method and partial differential equation method were introduced in detail. To reduce the computational cost, a partial differential equations method was used to control the geometry shape of centrifugal impellers parametrically, the boundary conditions of the equations were parameterized as well. Suppose the parameters a(u,v) are constant and the response surface methodology (RSM) was applied to optimize the design of centrifugal pump impellers, a 2nd order polynomial response surface was constructed according to the trial results. Unfortunately, it was identified that a 2nd order polynomial fails to present the complicated nonlinear relation between the objective function and the control variables. So the partial differential e-quations had to be proposed to construct the hypersurface response of objective function. Then a boundary-value problem of hyperspace was numerically solved. Eventually, an optimal design of pump impellers was achieved. The result of the optimized design case shows that the proposed theory and method are reasonable.%对离心泵叶轮优化设计存在的问题进行了详细的阐述,离心泵叶轮优化设计的主要困难在于复杂的内流道形状及其与泵水力性能间复杂的隐式关系,对基于NURBS的曲面设计方法、基于自由曲面变形方法及偏微分方程方法3种离心泵叶轮参数化设计方法的研究进行了详细的介绍,为了减少计算量,采用偏微分方程方法对离心泵叶片几何形状进行参数化控制,参数化控制偏微分方程的边界条件,假定方程中的控制参数a(u,v)为常量1,采用响应面方

  10. Esophageal capsule endoscopy

    Institute of Scientific and Technical Information of China (English)

    Ignacio Fernandez-Urien; Cristina Carretero; Raul Armendariz; Miguel Mu(n)oz-Navas

    2008-01-01

    Capsule endoscopy is now considered as the first imaging tool for small bowel examination.Recently,new capsule endoscopy applications have been developed,such as esophageal capsule endoscopy and colon capsule endoscopy.Esophageal capsule endoscopy in patients with suspected esophageal disorders is feasible and safe,and could be also an alternative procedure in those patients refusing upper endoscopy.Although large-scale studies are needed to confirm its utility in GERD and cirrhotic patients,current results are encouraging and open a new era in esophageal examination.

  11. Colon capsule endoscopy

    Institute of Scientific and Technical Information of China (English)

    Ignacio Fernandez-Urien; Cristina Carretero; Ana Borda; Miguel Mu(n)oz-Navas

    2008-01-01

    Wireless capsule endoscopy has become the first imaging tool for small bowel examination.Recently,new capsule endoscopy applications have been developed,such as esophageal capsule endoscopy and colon capsule endoscopy.Clinical trials results have shown that colon capsule endoscopy is feasible,accurate and safe in patients suffering from colonic diseases.It could be a good alternative in patients refusing conventional colonoscopy or when it is contraindicated.Upcoming studies are needed to demonstrate its utilty for colon cancer screening and other indications such us ulcerative colitis.Comparative studies including both conventional and virtual colonoscopy are also required.

  12. Magnetic control system targeted for capsule endoscopic operations in the stomach--design, fabrication, and in vitro and ex vivo evaluations.

    Science.gov (United States)

    Lien, Gi-Shih; Liu, Chih-Wen; Jiang, Joe-Air; Chuang, Cheng-Long; Teng, Ming-Tsung

    2012-07-01

    This paper presents a novel solution of a hand-held external controller to a miniaturized capsule endoscope in the gastrointestinal (GI) tract. Traditional capsule endoscopes move passively by peristaltic wave generated in the GI tract and the gravity, which makes it impossible for endoscopists to manipulate the capsule endoscope to the diagnostic disease areas. In this study, the main objective is to present an endoscopic capsule and a magnetic field navigator (MFN) that allows endoscopists to remotely control the locomotion and viewing angle of an endoscopic capsule. The attractive merits of this study are that the maneuvering of the endoscopic capsule can be achieved by the external MFN with effectiveness, low cost, and operation safety, both from a theoretical and an experimental point of view. In order to study the magnetic interactions between the endoscopic capsule and the external MFN, a magnetic-analysis model is established for computer-based finite-element simulations. In addition, experiments are conducted to show the control effectiveness of the MFN to the endoscopic capsule. Finally, several prototype endoscopic capsules and a prototype MFN are fabricated, and their actual capabilities are experimentally assessed via in vitro and ex vivo tests using a stomach model and a resected porcine stomach, respectively. Both in vitro and ex vivo test results demonstrate great potential and practicability of achieving high-precision rotation and controllable movement of the capsule using the developed MFN.

  13. Parametric (On-Design) Cycle Analysis for a Separate-Exhaust Turbofan Engine With Interstage Turbine Burner

    Science.gov (United States)

    Liew, K. H.; Urip, E.; Yang, S. L.; Siow, Y. K.; Marek, C. J.

    2005-01-01

    Today s modern aircraft is based on air-breathing jet propulsion systems, which use moving fluids as substances to transform energy carried by the fluids into power. Throughout aero-vehicle evolution, improvements have been made to the engine efficiency and pollutants reduction. The major advantages associated with the addition of ITB are an increase in thermal efficiency and reduction in NOx emission. Lower temperature peak in the main combustor results in lower thermal NOx emission and lower amount of cooling air required. This study focuses on a parametric (on-design) cycle analysis of a dual-spool, separate-flow turbofan engine with an Interstage Turbine Burner (ITB). The ITB considered in this paper is a relatively new concept in modern jet engine propulsion. The ITB serves as a secondary combustor and is located between the high- and the low-pressure turbine, i.e., the transition duct. The objective of this study is to use design parameters, such as flight Mach number, compressor pressure ratio, fan pressure ratio, fan bypass ratio, and high-pressure turbine inlet temperature to obtain engine performance parameters, such as specific thrust and thrust specific fuel consumption. Results of this study can provide guidance in identifying the performance characteristics of various engine components, which can then be used to develop, analyze, integrate, and optimize the system performance of turbofan engines with an ITB. Visual Basic program, Microsoft Excel macrocode, and Microsoft Excel neuron code are used to facilitate Microsoft Excel software to plot engine performance versus engine design parameters. This program computes and plots the data sequentially without forcing users to open other types of plotting programs. A user s manual on how to use the program is also included in this report. Furthermore, this stand-alone program is written in conjunction with an off-design program which is an extension of this study. The computed result of a selected design

  14. Parametric Flutter Analysis of the TCA Configuration and Recommendation for FFM Design and Scaling

    Science.gov (United States)

    Baker, Myles; Lenkey, Peter

    1997-01-01

    The current HSR Aeroelasticity plan to design, build, and test a full span, free flying transonic flutter model in the TDT has many technical obstacles that must be overcome for a successful program. One technical obstacle is the determination of a suitable configuration and point in the sky to use in setting the scaling point for the ASE models program. Determining this configuration and point in the sky requires balancing several conflicting requirements, including model buildability, tunnel test safety, and the ability of the model to represent the flutter mechanisms of interest. As will be discussed in detail in subsequent sections, the current TCA design exhibits several flutter mechanisms of interest. It has been decided that the ASE models program will focus on the low frequency symmetric flutter mechanism, and will make no attempt to investigate high frequency flutter mechanisms. There are several reasons for this choice. First, it is believed that the high frequency flutter mechanisms are similar in nature to classical wing bending/torsion flutter, and therefore there is more confidence that this mechanism can be predicted using current techniques. The low frequency mode, on the other hand, is a highly coupled mechanism involving wing, body, tail, and engine motion which may be very difficult to predict. Second, the high frequency flutter modes result in very small weight penalties (several hundred pounds), while suppression of the low frequency mechanism inside the flight envelope causes thousands of pounds to be added to the structure. In order to successfully test the low frequency flutter mode of interest, a suitable starting configuration and point in the sky must be identified. The configuration and point in the sky must result in a wind tunnel model that (1) represents the low-frequency wing/body/engine/empennage flutter mechanisms that are unique to HSCT configurations, (2) flutters at an acceptably low frequency in the tunnel, (3) flutters at an

  15. Advanced computational tools for PEM fuel cell design. Part 2. Detailed experimental validation and parametric study

    Science.gov (United States)

    Sui, P. C.; Kumar, S.; Djilali, N.

    This paper reports on the systematic experimental validation of a comprehensive 3D CFD-based computational model presented and documented in Part 1. Simulations for unit cells with straight channels, similar to the Ballard Mk902 hardware, are performed and analyzed in conjunction with detailed current mapping measurements and water mass distributions in the membrane-electrode assembly. The experiments were designed to display sensitivity of the cell over a range of operating parameters including current density, humidification, and coolant temperature, making the data particularly well suited for systematic validation. Based on the validation and analysis of the predictions, values of model parameters, including the electro-osmotic drag coefficient, capillary diffusion coefficient, and catalyst specific surface area are determined adjusted to fit experimental data of current density and MEA water content. The predicted net water flux out of the anode (normalized by the total water generated) increases as anode humidification water flow rate is increased, in agreement with experimental results. A modification of the constitutive equation for the capillary diffusivity of water in the porous electrodes that attempts to incorporate the experimentally observed immobile (or irreducible) saturation yields a better fit of the predicted MEA water mass with experimental data. The specific surface area parameter used in the catalyst layer model is found to be effective in tuning the simulations to predict the correct cell voltage over a range of stoichiometries.

  16. UG-based Parametric Design for Rail Cars%基于 UG 的轨道架车参数化设计

    Institute of Scientific and Technical Information of China (English)

    陈超; 王耕耘; 张文明

    2016-01-01

    This paper studies the parametric design system of rail cars based on UG platform ,realizing the parametric design of rail cars ,and achieving a very good benefit in practical applications as well .It puts emphasis on the design of module reuse technology and automated assembly method of standard parts ,and solves the main problems in the process of parametric design on product level .%研究了基于UG的轨道架车参数化设计系统,实现了轨道架车的参数化设计,在实际应用中取得了很好的效果。同时研究了复杂变形设计中的模块重用技术和标准件的自动化装配方法,解决了产品级参数化设计过程中的主要问题。

  17. Parametric Design of Safety Door with Inventor Parameterization%基于 Inventor 参数化的安全门设计

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

      从外购件的选用和机加件的设计阐述了自动化生产线安全门的设计思路。利用Inventor强大的参数化功能,依据各零件之间的装配关系,在Excel表格中建立各零件之间的数学关联式,并导入Inventor软件中建立安全门参数化模型,为其他类似机构设计提供了参考。参数化模型方法简单、方便、有助于提高设计效率和生产周期,并可以为模块化设计提供依据。%A design idea of safety door in automatic production line was described in aspects of parchased part selection and machined part design .Based on the assembly relationship of parts ,the mathematical relationship of parts was set up in Excel and imported into Inventor ,then the parametric model of the safety door was established by the powerful parametric function of Inventor .This work will provide some reference for the design of other similar mechanism .The method of parametric modeling is simple ,convenient and helping to improve the design efficiency and production cycle .

  18. Comparisons of Wilson-Fowler and Parametric Cubic Splines with the Curve-Fitting Algorithms of Several Computer-Aided Design Systems

    Energy Technology Data Exchange (ETDEWEB)

    Birchler, W.D.; Schilling, S.A.

    2001-02-01

    The purpose of this report is to demonstrate that modern computer-aided design (CAD), computer-aided manufacturing (CAM), and computer-aided engineering (CAE) systems can be used in the Department of Energy (DOE) Nuclear Weapons Complex (NWC) to design new and remodel old products, fabricate old and new parts, and reproduce legacy data within the inspection uncertainty limits. In this study, two two-dimensional splines are compared with several modern CAD curve-fitting modeling algorithms. The first curve-fitting algorithm is called the Wilson-Fowler Spline (WFS), and the second is called a parametric cubic spline (PCS). Modern CAD systems usually utilize either parametric cubic and/or B-splines.

  19. Parametric Design of Hydrodynamic Coupling%液力偶合器参数化设计系统的开发

    Institute of Scientific and Technical Information of China (English)

    刘刚

    2012-01-01

    利用UG二次开发,对液力偶合器进行参数化设计,并开发液力偶合器参数化设计系统。通过改变偶合器的5个参数:有效直径、腔型半径、叶片缩进距离、叶片数量、泵轮与涡轮间隙,得到满足需求的偶合器三维图形。%Parametric design of the hydrodynamic coupling is proposed using the secondary development of UG, and exploiting parametric design system of hydrodynamic coupling. Through changing the five different parameters, namely, effective diameter, chamber radius, blade indent distance, blade number, and interspace between pump and turbine, the three dimensional model of coupling which suffice the requirement is achieved.

  20. Finite element analysis as a tool for parametric prosthetic foot design and evaluation. Technique development in the solid ankle cushioned heel (SACH) foot.

    Science.gov (United States)

    Saunders, Marnie M; Schwentker, Edwards P; Kay, David B; Bennett, Gordon; Jacobs, Christopher R; Verstraete, Mary C; Njus, Glen O

    2003-02-01

    In this study, we developed an approach for prosthetic foot design incorporating motion analysis, mechanical testing and computer analysis. Using computer modeling and finite element analysis, a three-dimensional (3D), numerical foot model of the solid ankle cushioned heel (SACH) foot was constructed and analyzed based upon loading conditions obtained from the gait analysis of an amputee and validated experimentally using mechanical testing. The model was then used to address effects of viscoelastic heel performance numerically. This is just one example of the type of parametric analysis and design enabled by this approach. More importantly, by incorporating the unique gait characteristics of the amputee, these parametric analyses may lead to prosthetic feet more appropriately representing a particular user's needs, comfort and activity level.

  1. 微量药品单元动态称重系统的设计与实现%Design and realization of micro scale capsule dynamic weighing system

    Institute of Scientific and Technical Information of China (English)

    庄育锋; 翟宇

    2013-01-01

    The design method for a micro scale capsule dynamic weighing system is proposed, which can transport and classify capsules in turn and acquire the quality of the capsules. A kind of kinetic model for the dynamic weighing of capsule is established. The model is based on energy conservation principle and considers the influences of sliding chute parameters, sensor parameters and other factors. The movement process of the capsules with different weights is analyzed. MATLAB is adopted to simulate the analysis results. During the process of transporting and classifying the capsules,the weighing transducer is used to measure the weight of the capsule. The A/D converter, which is linked to the weighing transducer, sends the capsule weight data to the subsequent ARM processor. The ARM processor sends data to MCU that controls the movement of the electric motor through serial communication and the observing and controlling process is completed. Meanwhile, a graphic user interface is developed based on miniGUI, with which the ARM processor can display the capsule weight information in real time. The simulation and experiment results indicate that when the threshold of the sensor signal is 0. 195 V and the time interval of the weighing process is 1.46 s, the dynamic capsule weighing process can be realized successfully. The design for capsule weighing unit has completed the process of capsules weighing effectively and improves the reliability and high efficiency of capsule dynamic condition weighing.%提出了一种微量药品单元动态称重系统的设计方法,可依次完成药品单元的传送和分拨,并统计药品单元的质量情况.建立了药品单元动态称重的动力学模型,模型以能量守恒原理为基础,考虑了滑槽截面参数、传感器参数等因素,对不同质量药品单元的运动过程进行了分析,并利用MATLAB对分析结果进行了仿真.系统对药品单元的传送、分拨控制过程是利用称重传感

  2. The Parametric and Building Information Modelling upon Architectural Design Practice%基于设计实践的参数化与BIM

    Institute of Scientific and Technical Information of China (English)

    高岩

    2014-01-01

    The Parametric and bIm have become the two popular words often mentioned by architects. It was only about five years ago when few actualy understood what they were, but nowadays almost everyone can talk about them. Whereas, the Parametric has been regarded as the representative of complex form, meanwhile, there are many versions of bIm interpretation in China. Some even stack up the Parametric and bIm, as wel as many other popular words such as Non-linear, and Algorithmic, somehow exposing the significant malposition of the purposes and the processes of applying the digital techniques. In order to comprehend what is the Parametric, bIm, and their relationships, we must discuss themin the context of architectural design practice. This article starts from investigating the comprehensive meaning of the Parametric and bIm based upon the understanding of generalized design activities. Then, it employs the Four Quadrants framework by Ken Wilber to elaborate the relationships between bIm and design, between the Parametric and design, and between the Parametric and bIm, before looking forward into the future directions. In the end, the conclusion was summarized as that no matter the Parametric or bIm, they are al the vehicles but not the destinations, the processes but not the purposes. Only when we understand their relationships upon architectural design practice, can we improve the colective efficiency and the design qualities of the team without constraining individual designers’ intuitive and heuristic creativities.%参数化与bIm这两个词越来越多地被建筑师们挂在嘴上,在中国从鲜有人知到谁都能说点,也就是过去三、五年的事情。时至今日,参数化已经成为复杂形体的代词,对于bIm的理解也是众说纷纭,有人甚至把参数化和bIm等“时髦”的词语罗列在一起,暴露了对于这些数字化技术应用背后本质和动机的错位。要想真正领悟什么是参数化,什么是bIm,

  3. Development of Cubic Bezier Curve and Curve-Plane Intersection Method for Parametric Submarine Hull Form Design to Optimize Hull Resistance Using CFD

    Institute of Scientific and Technical Information of China (English)

    Deddy Chrismianto; Ahmad Fauzan Zakki; Berlian Arswendo; Dong Joon Kim

    2015-01-01

    Optimization analysis and computational fluid dynamics (CFDs) have been applied simultaneously, in which a parametric model plays an important role in finding the optimal solution. However, it is difficult to create a parametric model for a complex shape with irregular curves, such as a submarine hull form. In this study, the cubic Bezier curve and curve-plane intersection method are used to generate a solid model of a parametric submarine hull form taking three input parameters into account: nose radius, tail radius, and length-height hull ratio (L/H). Application program interface (API) scripting is also used to write code in the ANSYS DesignModeler. The results show that the submarine shape can be generated with some variation of the input parameters. An example is given that shows how the proposed method can be applied successfully to a hull resistance optimization case. The parametric design of the middle submarine type was chosen to be modified. First, the original submarine model was analyzed, in advance, using CFD. Then, using the response surface graph, some candidate optimal designs with a minimum hull resistance coefficient were obtained. Further, the optimization method in goal-driven optimization (GDO) was implemented to find the submarine hull form with the minimum hull resistance coefficient (Ct). The minimum Ct was obtained. The calculated difference in Ct values between the initial submarine and the optimum submarine is around 0.26%, with the Ct of the initial submarine and the optimum submarine being 0.001 508 26 and 0.001 504 29, respectively. The results show that the optimum submarine hull form shows a higher nose radius (rn) and higher L/H than those of the initial submarine shape, while the radius of the tail (rt) is smaller than that of the initial shape.

  4. Development of cubic Bezier curve and curve-plane intersection method for parametric submarine hull form design to optimize hull resistance using CFD

    Science.gov (United States)

    Chrismianto, Deddy; Zakki, Ahmad Fauzan; Arswendo, Berlian; Kim, Dong Joon

    2015-12-01

    Optimization analysis and computational fluid dynamics (CFDs) have been applied simultaneously, in which a parametric model plays an important role in finding the optimal solution. However, it is difficult to create a parametric model for a complex shape with irregular curves, such as a submarine hull form. In this study, the cubic Bezier curve and curve-plane intersection method are used to generate a solid model of a parametric submarine hull form taking three input parameters into account: nose radius, tail radius, and length-height hull ratio ( L/ H). Application program interface (API) scripting is also used to write code in the ANSYS design modeler. The results show that the submarine shape can be generated with some variation of the input parameters. An example is given that shows how the proposed method can be applied successfully to a hull resistance optimization case. The parametric design of the middle submarine type was chosen to be modified. First, the original submarine model was analyzed, in advance, using CFD. Then, using the response surface graph, some candidate optimal designs with a minimum hull resistance coefficient were obtained. Further, the optimization method in goal-driven optimization (GDO) was implemented to find the submarine hull form with the minimum hull resistance coefficient ( C t ). The minimum C t was obtained. The calculated difference in C t values between the initial submarine and the optimum submarine is around 0.26%, with the C t of the initial submarine and the optimum submarine being 0.001 508 26 and 0.001 504 29, respectively. The results show that the optimum submarine hull form shows a higher nose radius ( r n ) and higher L/ H than those of the initial submarine shape, while the radius of the tail ( r t ) is smaller than that of the initial shape.

  5. 基于Pro/E及ANSYS的涡旋盘参数化设计%The Parametric Design of Orbiter Based on Pro/E and ANSYS

    Institute of Scientific and Technical Information of China (English)

    刘涛; 熊珊

    2012-01-01

    This paper uses the Program of Pro/E on the characteristic parameters of the orbiter to get the establishment of the scrolls parametric design model, and uses the ADPL of ANSYS program on the structural parameters of the orbiter to get the establishment of the scrolls parametric analysis model. As the design result shows, the parametric design of the orbiter based on Pro/E and ANSYS effectively solve the problem that using the orbiter model which is created by three-dimensional CAD design software is imported ANSYS as a analysis model can not be recycled,and improve the efficiency of the design and analysis on the orbiter,it has great significance to achieve CAD/CAE integration system of scroll compressor.%利用Pro/E的Program对涡旋盘的特征参数编程建立了涡旋盘的参数化设计模型,同时利用ANSYS的ADPL对涡旋盘的结构参数编程建立了涡旋盘的参数化分析模型.设计结果表明,基于Pro/E及ANSYS的涡旋盘参数化设计,有效地解决了利用三维CAD设计软件,建立的涡旋盘模型导入ANSYS中作为分析模型无法再生的问题,提高了涡旋盘的设计及分析效率,对实现涡旋压缩机的CAD/CAE一体化系统研究具有重要意义.

  6. Design and implementation of parametric stereo encoder in MDFT domain.%MDFT域参数立体声编码器设计与实现

    Institute of Scientific and Technical Information of China (English)

    曾敏; 涂卫平; 蔡旭芬

    2016-01-01

    Parametric stereo coding in FFT domain uses different time-frequency transforms in core encoder and stereo parameter extraction module, which leading to high computational load. A parametric stereo codec based on MDFT(Modi-fied Discrete Fourier Transform)is designed and implemented so that the same transform—MDCT(Modified Discrete Cosine Transform)be reused in down mixing channel coding and parameter extraction, thereby computational complexity can be reduced efficiently. Test results show that this codec provides comparable audio quality with the computational complexity reduction by 33% compared to the classical parametric stereo codec in FFT domain. Existing theory of para-metric stereo coding in MDFT domain is completed and verified.%FFT域参数立体声编码器在立体声参数提取和主声道编码时采用不同的时频变换,导致计算复杂度高.设计并实现了一种MDFT(Modified Discrete Fourier Transform,修正离散傅里叶变换)域参数立体声编码器,使得立体声参数提取和主声道编码部分能够复用MDCT(Modified Discrete Cosine Transform,修正离散余弦变换)变换,从而有效降低计算复杂度.与经典的FFT域参数立体声编码器相比,在保证音质相当的同时,编解码计算复杂度下降约33%.完善并验证了已有的MDFT域参数立体声编码理论.

  7. Capsule development and utilization for material irradiation tests

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Young Hwan; Kim, B. G.; Joo, K. N. [and others

    2000-05-01

    The development program of advanced nuclear structural and fuel materials includes the in-pile tests using the instrumented capsule at HANARO. The tests were performed in the in-core test holes of CT, IR 1 and 2 and OR 4 and 5 of HANARO. Extensive efforts have also been made to establish design and manufacturing technology for the instrumented capsule and its related system, which should be compatible with the HANARO's characteristics. Since the first instrumented capsule(97M-01K) had been designed and successfully fabricated, five tests were done to support the users and provided the economic benefits to user by generating the essential in-pile information on the performance and structural integrity of materials. This paper describes the present status and future plans of these R and D activities for the development of the instrumented capsule including in-situ material property measurement capsules and nuclear fuel test capsules.

  8. Application of parametric manikin in virtual product design%参数化人体模型在虚拟产品设计中的应用

    Institute of Scientific and Technical Information of China (English)

    张守京; 王爽; 宋栓军

    2015-01-01

    In order to improve the efficiency of ergonomics design ,the design method of virtual product model based on parametric manikin was put forward .Based on the body measurement data ,anthropometric database design was standardized ,the design of the human body model was carried out by parametric method by which .The anthropometric data mapping by a specific encoding process became a virtual product design required size by operating human body on UG platform .The method was testified by virtual model design example and the results show that it effectively simplifies the design process and improves the working efficiency .%为提高人机设计效率,提出了基于参数化人体模型的虚拟产品模型的设计方法。以人体测量数据为基础进行标准化人体测量数据库设计,并基于人体测量数据库以参数化方法进行人体模型的设计。在UG平台上通过操作人体模型将人体测量数据经过特定的编码程序映射成为虚拟产品设计所需尺寸,通过座椅虚拟模型的人机设计实例对该方法进行验证。结果表明,该方法简化了设计过程,提高了虚拟产品模型设计效率。

  9. MEMS digital parametric loudspeaker

    KAUST Repository

    Carreno, Armando Arpys Arevalo

    2016-03-23

    This paper reports on the design and fabrication of MEMS actuator arrays suitable for Digital Sound reconstruction and Parametric Directional Loudspeakers. Two distinct versions of the device were fabricated: one using the electrostatic principle actuation and the other one, the piezoelectric principle. Both versions used similar membrane dimensions, with a diameter of 500 μm. These devices are the smallest Micro-Machined Ultrasound Transducer (MUT) arrays that can be operated for both modes: Digital Sound Reconstruction and Parametric Loudspeaker. The chips consist of an array with 256 transducers, in a footprint of 12 mm by 12 mm. The total single chip size is: 2.3 cm by 2.3 cm, including the contact pads. © 2016 IEEE.

  10. Reduced models and design principles for half-harmonic generation in synchronously-pumped optical parametric oscillators

    CERN Document Server

    Hamerly, Ryan; Jankowski, Marc; Fejer, Martin M; Yamamoto, Yoshihisa; Mabuchi, Hideo

    2016-01-01

    We develop reduced models that describe half-harmonic generation in a synchronously-pumped optical parametric oscillator above threshold, where nonlinearity, dispersion, and group-velocity mismatch are all relevant. These models are based on (1) an eigenmode expansion for low pump powers, (2) a simulton-like sech-pulse ansatz for intermediate powers, and (3) dispersionless box-shaped pulses for high powers. Analytic formulas for pulse compression, degenerate vs. nondegenerate operation, and stability are derived and compared to numerical and experimental results.

  11. Engineering Stable Hollow Capsules

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    @@ Scientists at the CAS Institute of Chemistry have been succeeded in fabricating stable hollow capsules by extending covalent layer-by-layer self-assembly(CSA)technique from 2-dimensional to 3-dimensional systems.

  12. Basic ammonothermal GaN growth in molybdenum capsules

    Science.gov (United States)

    Pimputkar, S.; Speck, J. S.; Nakamura, S.

    2016-12-01

    Single crystal, bulk gallium nitride (GaN) crystals were grown using the basic ammonothermal method in a high purity growth environment created using a non-hermetically sealed molybdenum (Mo) capsule and compared to growths performed in a similarly designed silver (Ag) capsule and capsule-free René 41 autoclave. Secondary ion mass spectrometry (SIMS) analysis revealed transition metal free (<1×1017 cm-3) GaN crystals. Anomalously low oxygen concentrations ((2-6)×1018 cm-3) were measured in a {0001} seeded crystal boule grown using a Mo capsule, despite higher source material oxygen concentrations ((1-5)×1019 cm-3) suggesting that molybdenum (or molybdenum nitrides) may act to getter oxygen under certain conditions. Total system pressure profiles from growth runs in a Mo capsule system were comparable to those without a capsule, with pressures peaking within 2 days and slowly decaying due to hydrogen diffusional losses. Measured Mo capsule GaN growth rates were comparable to un-optimized growth rates in capsule-free systems and appreciably slower than in Ag-capsule systems. Crystal quality replicated that of the GaN seed crystals for all capsule conditions, with high quality growth occurring on the (0001) Ga-face. Optical absorption and impurity concentration characterization suggests reduced concentrations of hydrogenated gallium vacancies (VGa-Hx).

  13. Capsule contraction syndrome

    Directory of Open Access Journals (Sweden)

    Mesut COŞKUN

    2009-06-01

    Full Text Available Capsule contraction syndrome occurs after fibrous metaplasia of lens proteins that leads to capsular bag contraction. Excessive front capsular wrinkling is seen in capsule contraction syndrome and there is an imbalance between powers supplying capsular integrity. This situation leads to zonular weakness. Capsule contraction syndrome is associated with pseudoexfoliation, older age, uveitis, pars planitis and myotonic muscular dystrophy. In order to decrease the risk of capsule contraction syndrome, front capsulerhexis area should be open as 5.5-6 mm diameter and a curysoft intraocular lens should be used. In order to prevent lens epithelial proliferation and metaplasia, lens epithelial cells at inferior surface of front capsule should be aspirated carefully. If postoperative capsular contraction detected, front capsulotomy should be performed by Nd-YAG laser at postoperative 2 to 3 weeks. In patients that Nd-YAG laser is unsuccessful, capsular tension should be decreased by surgical microincisions. In present study, we evaluated etiology, prevention and management of capsule contraction syndrome in the light of actual literature knowledge.

  14. Regional multiaxial mechanical properties of the porcine anterior lens capsule.

    Science.gov (United States)

    David, G; Pedrigi, R M; Heistand, M R; Humphrey, J D

    2007-02-01

    The lens capsule of the eye plays fundamental biomechanical roles in both normal physiological processes and clinical interventions. There has been modest attention given to the mechanical properties of this important membrane, however, and prior studies have focused on 1-D analyses of the data. We present results that suggest that the porcine anterior lens capsule has a complex, regionally dependent, nonlinear, anisotropic behavior. Specifically, using a subdomain inverse finite element method to analyze data collected via a new biplane video-based test system, we found that the lens capsule is nearly isotropic (in-plane) near the pole but progressively stiffer in the circumferential compared to the meridional direction as one approaches the equator. Because the porcine capsule is a good model of the young human capsule, there is strong motivation to determine if similar regional variations exist in the human lens capsule for knowledge of such complexities may allow us to improve the design of surgical procedures and implants.

  15. Polar tent for reduced perturbation of NIF ignition capsules

    Science.gov (United States)

    Hammel, B. A.; Pickworth, L.; Stadermann, M.; Field, J.; Robey, H.; Scott, H. A.; Smalyuk, V.

    2016-10-01

    In simulations, a tent that contacts the capsule near the poles and departs tangential to the capsule surface greatly reduces the capsule perturbation, and the resulting mass injected into the hot-spot, compared to current capsule support methods. Target fabrication appears feasible with a layered tent (43-nm polyimide + 8-nm C) for increased stiffness. We are planning quantitative measurements of the resulting shell- ρR perturbation near peak implosion velocity (PV) using enhanced self-emission backlighting, achieved by adding 1% Ar to the capsule fill in Symcaps (4He + H). Layered DT implosions are also planned for an integrated test of capsule performance. We will describe the design and simulation predictions. Prepared by LLNL under Contract DE-AC52-07NA27344.

  16. Parametric logic: Foundations

    Institute of Scientific and Technical Information of China (English)

    林作铨; 李未

    1995-01-01

    Parametric logic is introduced. The language, semantics and axiom system of parametric logic are defined. Completeness theorem of parametric logic is provided. Parametric logic has formal ability powerful enough to capture a wide class of logic as its special cases, and therefore can be viewed as a uniform basis for modern logics.

  17. Optimal Design of Dual-Pump Fibre-Optical Parametric Amplifiers with Dispersion Fluctuations Based on Hybrid Genetic Algorithm

    Institute of Scientific and Technical Information of China (English)

    LIU Xue-Ming; LI Yan-He

    2005-01-01

    @@ Solutions of dual-pump fibre-optical parametric amplifiers (DP-FOPAs) with dispersion fluctuations are derived by using a matrix operator. Based on these solutions and a hybrid genetic algorithm, we have optimized threesection DP-FOPAs to increase the signal band and improve the gain uniformity. The optimizations demonstrate that when dispersion fluctuations are taken into account, the 44-nm signal band with the 0.37-dB ripple and over 14.8-dB gain can be obtained from the three-section DP-FOPA, instead of the lowest gain of ~13dB with the ripple of more than 15dB from the single-section DP-FOPA.

  18. Design of passive cooling by night ventilation: evaluation of a parametric model and building simulation with measurements

    Energy Technology Data Exchange (ETDEWEB)

    Pfafferott, J.; Herkel, S.; Jaeschke, M. [Fraunhofer-Institute for Solar Energy Systems, Freiburg (Germany)

    2003-12-01

    At the new institute building of Fraunhofer ISE, both mechanical and free night ventilation is used for passive cooling of the offices. The results from a long-term monitoring show, that room temperatures are comfortable even at high ambient air temperatures. In two offices, experiments were carried out in order to determine the efficiency of night ventilation dependent on air change rate, solar and internal heat gains. The aim is to identify characteristic building parameters and to determine the night ventilation effect with these parameters. The experiments (one room with and one without night ventilation) are evaluated by using both a parametric model and the ESP-r building simulation programme. Both models are merged in order to develop a method for data evaluation in office buildings with night ventilation and to provide a simple model for integration in a building management system. (Author)

  19. The capsule's contribution to total hip construct stability--a finite element analysis.

    Science.gov (United States)

    Elkins, Jacob M; Stroud, Nicholas J; Rudert, M James; Tochigi, Yuki; Pedersen, Douglas R; Ellis, Benjamin J; Callaghan, John J; Weiss, Jeffrey A; Brown, Thomas D

    2011-11-01

    Instability is a significant concern in total hip arthroplasty (THA), particularly when there is structural compromise of the capsule due to pre-existing pathology or due to necessities of surgical approach. An experimentally grounded fiber-direction-based finite element model of the hip capsule was developed, and was integrated with an established three-dimensional model of impingement/dislocation. Model validity was established by close similarity to results from a cadaveric experiment in a servohydraulic hip simulator. Parametric computational runs explored effects of graded levels of capsule thickness, of regional detachment from the capsule's femoral or acetabular insertions, of surgical incisions of capsule substance, and of capsule defect repairs. Depending strongly upon the specific site, localized capsule defects caused varying degrees of construct stability compromise, with several specific situations involving over 60% decrement in dislocation resistance. Construct stability was returned substantially toward intact-capsule levels following well-conceived repairs, although the suture sites involved were often at substantial risk of failure. These parametric model results underscore the importance of retaining or robustly repairing capsular structures in THA, in order to maximize overall construct stability. 

  20. Risk factors for incomplete small-bowel capsule endoscopy

    NARCIS (Netherlands)

    Westerhof, Jessie; Weersma, Rinse K.; Koornstra, Jan J.

    2009-01-01

    Background: In 20% to 30% of capsule endoscopy (CE) procedures, the capsule does not reach the cecum within recording time, with incomplete imaging of the small bowel, which limits the value of CE. Objective: To identify possible risk factors for incomplete small-bowel CE examinations. Design: Data

  1. NIF capsule performance modeling

    Directory of Open Access Journals (Sweden)

    Weber S.

    2013-11-01

    Full Text Available Post-shot modeling of NIF capsule implosions was performed in order to validate our physical and numerical models. Cryogenic layered target implosions and experiments with surrogate targets produce an abundance of capsule performance data including implosion velocity, remaining ablator mass, times of peak x-ray and neutron emission, core image size, core symmetry, neutron yield, and x-ray spectra. We have attempted to match the integrated data set with capsule-only simulations by adjusting the drive and other physics parameters within expected uncertainties. The simulations include interface roughness, time-dependent symmetry, and a model of mix. We were able to match many of the measured performance parameters for a selection of shots.

  2. 77 FR 66621 - Draft Guidance for Industry on Bioequivalence Recommendation for Lenalidomide Capsules; Availability

    Science.gov (United States)

    2012-11-06

    ... availability of revised draft BE recommendations for lenalidomide capsules. Revlimid (lenalidomide capsules.... Revlimid is designated as the reference listed drug, and therefore any ANDAs for generic lenalidomide capsules must demonstrate BE to the Revlimid prior to approval. There are no approved ANDAs for...

  3. Comparative Study and Improvement Design on Aerodynamic Charac-teristics of Typical Reentry Capsules%典型再入返回器气动特性对比与改进研究

    Institute of Scientific and Technical Information of China (English)

    詹慧玲; 陈冰雁; 刘周; 周伟江

    2013-01-01

    返回器气动特性研究对宇宙飞船的研制起着先导和制约作用。文章对 Apollo、CEV 和类Soyuz这3种典型的轴对称钝头体再入返回器气动布局进行了气动特性的对比分析,发现与Apollo、CEV相比,类Soyuz外形的升阻比偏小,无法满足以第二宇宙速度载人空间再入返回的要求。在此基础上研究了几何参数(包括倒锥角和球冠半径)变化对类Soyuz外形返回器气动性能的影响规律,从中得到类Soyuz 外形的改进方向,提出了一种以类 Soyuz 外形为基础的改进设计外形,并对该外形的升阻特性、稳定性和配平特性等相关气动特性进行了分析。研究表明通过对几何外形参数的调整优化来提高类Soyuz外形的升阻比,从而达到以第二宇宙速度再入返回的升阻比要求,这样的技术途径是可行的。%The aerodynamic characteristics investigation of reentry capsule plays an important role in the design of spacecraft. Comparative analysis of the aerodynamics between Soyuz and Apollo/CEV configurations is accomplished in this paper. The lift-to-drag ratio of Soyuz which is lower than that of Apollo/CEV cannot meet the requirement of manned capsule reentry at second cosmic velocity from space. The influence of geo-metric parameters, including after-body angle and heat shield radius, on the aerodynamic characteristics of Soyuz configuration is analyzed. And a modified configuration is suggested on the basis of Soyuz. The aerody-namic characteristics of the modified configuration are analyzed, including lift-to-drag ratio, stability, and trim characteristics. The results show that adjusting and optimizing the geometric parameters of Soyuz re-entry capsule is a feasible way for designing a capsule configuration to meet the high lift-to-drag ratio requirement of manned capsule reentry at second cosmic velocity.

  4. Wireless capsule endoscopy

    Institute of Scientific and Technical Information of China (English)

    A Mata; J Llach; JM Bordas

    2008-01-01

    Wireless capsule endoscopy is a new technique that allows complete exploration of the small bowel without external wires. Its role has been analyzed in many small bowel diseases such as obscure gastrointestinal bleeding, Crohn's disease and gastrointestinal polyposis syndromes with promising results. Studies on other pathologies (I.e. Small bowel tumour, celiac disease) are under evaluation to define the role of this technique.

  5. Parametrizing Algebraic Curves

    OpenAIRE

    Lemmermeyer, Franz

    2011-01-01

    We present the technique of parametrization of plane algebraic curves from a number theorist's point of view and present Kapferer's simple and beautiful (but little known) proof that nonsingular curves of degree > 2 cannot be parametrized by rational functions.

  6. Parametric programming of industrial robots

    Directory of Open Access Journals (Sweden)

    Szulczyński Paweł

    2015-06-01

    Full Text Available This article proposes the use of parametric design software, commonly used by architects, in order to obtain complex trajectory and program code for industrial robots. The paper describes the drawbacks of existing solutions and proposes a new script to obtain a correct program. The result of the algorithm was verified experimentally.

  7. Development of Parametric Designing and Drawing System Based on Pro%基于Pro/E的参数化设计及绘图系统的开发

    Institute of Scientific and Technical Information of China (English)

    陶宇; 平雪良; 董宁; 叶晶

    2011-01-01

    In view of the actual situation that the characteristics of the same topological structure and different dimension parameters in the course of Product seriation, using Pro/E's function of parametric modeling and second development tool-Pro/ToolKit we develop a parameteric designing and drawing system which meets the company's needs. Firstly, it is necessary to set up 3D parametric model;Secondly, based on the API functions offered by Pro/ToolKit, the system can edit data interface on the operating platform of MFC, achieve the seamless linking among Pro/ToolKit, Pro/E and MFC, and have the nature of interactivity, visibility,pertinence;Finally, users entery to the system, input data, complete the auto-generation of parts and drawings. The system make us avoid duplication of work in the course of Product seriation, enhance efficiency greatly.%针对产品系列化制造中存在的拓扑结构相同、尺寸参数不旧的情况,借助Pro/E参数化建模功能及其二次开发工具Pro/ToolKit,开发满足企业实际需求的参数化没计及绘图系统.首先,创建三维参数化模型;其次,以Pro/ToolKit提供的API函购数为基础,以MFC为操作平台编辑数据接口,实现Pro/ToolKit、Pro/E与MFC的无缝链接,具备交互性、可视性、针对性;最后,进入系统,输入参数,实现零什和工程图的自动生成.该系统有效避免了系列化设计中重复性劳动,大大提高了设计效率.

  8. Analysing intracellular deformation of polymer capsules using structured illumination microscopy

    Science.gov (United States)

    Chen, Xi; Cui, Jiwei; Sun, Huanli; Müllner, Markus; Yan, Yan; Noi, Ka Fung; Ping, Yuan; Caruso, Frank

    2016-06-01

    Understanding the behaviour of therapeutic carriers is important in elucidating their mechanism of action and how they are processed inside cells. Herein we examine the intracellular deformation of layer-by-layer assembled polymer capsules using super-resolution structured illumination microscopy (SIM). Spherical- and cylindrical-shaped capsules were studied in three different cell lines, namely HeLa (human epithelial cell line), RAW264.7 (mouse macrophage cell line) and differentiated THP-1 (human monocyte-derived macrophage cell line). We observed that the deformation of capsules was dependent on cell line, but independent of capsule shape. This suggests that the mechanical forces, which induce capsule deformation during cell uptake, vary between cell lines, indicating that the capsules are exposed to higher mechanical forces in HeLa cells, followed by RAW264.7 and then differentiated THP-1 cells. Our study demonstrates the use of super-resolution SIM in analysing intracellular capsule deformation, offering important insights into the cellular processing of drug carriers in cells and providing fundamental knowledge of intracellular mechanobiology. Furthermore, this study may aid in the design of novel drug carriers that are sensitive to deformation for enhanced drug release properties.Understanding the behaviour of therapeutic carriers is important in elucidating their mechanism of action and how they are processed inside cells. Herein we examine the intracellular deformation of layer-by-layer assembled polymer capsules using super-resolution structured illumination microscopy (SIM). Spherical- and cylindrical-shaped capsules were studied in three different cell lines, namely HeLa (human epithelial cell line), RAW264.7 (mouse macrophage cell line) and differentiated THP-1 (human monocyte-derived macrophage cell line). We observed that the deformation of capsules was dependent on cell line, but independent of capsule shape. This suggests that the mechanical forces

  9. Management of adhesive capsulitis

    Directory of Open Access Journals (Sweden)

    Stupay KL

    2015-08-01

    Full Text Available Kristen L Stupay,1 Andrew S Neviaser2 1Tulane University School of Medicine, New Orleans, LA, USA; 2George Washington University Medical Faculty Associates, Washington, DC, USA Abstract: Adhesive capsulitis of the shoulder is a condition of capsular contracture that reduces both active and passive glenohumeral motion. The cause of adhesive capsulitis is not known but it is strongly associated with endocrine abnormalities such as diabetes. Diverse terminology and the absence of definitive criteria for diagnosis make evaluating treatment modalities difficult. Many treatment methods have been reported, most with some success, but few have been proved to alter the natural course of this disease. Most afflicted patients will achieve acceptable shoulder function without surgery. Those who remain debilitated after 8–12 months are reasonable candidates for invasive treatments. Here, the various treatment methods and the data to support their use are reviewed. Keywords: frozen shoulder, stiff shoulder, periarthritis, painful shoulder 

  10. On Parametric (and Non-Parametric Variation

    Directory of Open Access Journals (Sweden)

    Neil Smith

    2009-11-01

    Full Text Available This article raises the issue of the correct characterization of ‘Parametric Variation’ in syntax and phonology. After specifying their theoretical commitments, the authors outline the relevant parts of the Principles–and–Parameters framework, and draw a three-way distinction among Universal Principles, Parameters, and Accidents. The core of the contribution then consists of an attempt to provide identity criteria for parametric, as opposed to non-parametric, variation. Parametric choices must be antecedently known, and it is suggested that they must also satisfy seven individually necessary and jointly sufficient criteria. These are that they be cognitively represented, systematic, dependent on the input, deterministic, discrete, mutually exclusive, and irreversible.

  11. Capsule-train stability

    Science.gov (United States)

    Bryngelson, Spencer H.; Freund, Jonathan B.

    2016-07-01

    Elastic capsules flowing in small enough tubes, such as red blood cells in capillaries, are well known to line up into regular single-file trains. The stability of such trains in somewhat wider channels, where this organization is not observed, is studied in a two-dimensional model system that includes full coupling between the viscous flow and suspended capsules. A diverse set of linearly amplifying disturbances, both long-time asymptotic (modal) and transient (nonmodal) perturbations, is identified and analyzed. These have a range of amplification rates and their corresponding forms are wavelike, typically dominated by one of five principal perturbation classes: longitudinal and transverse translations, tilts, and symmetric and asymmetric shape distortions. Finite-amplitude transiently amplifying perturbations are shown to provide a mechanism that can bypass slower asymptotic modal linear growth and precipitate the onset of nonlinear effects. Direct numerical simulations are used to verify the linear analysis and track the subsequent transition of the regular capsule trains into an apparently chaotic flow.

  12. Conceptual design of sustainable integrated microalgae biorefineries: Parametric analysis of energy use, greenhouse gas emissions and techno-economics

    NARCIS (Netherlands)

    Posada, John A.; Brentner, Laura B.; Ramirez, Andrea; Patel, Martin K.

    2016-01-01

    This study covers four main aspects of the conceptual design of sustainable integrated microalgae-based biorefineries using flue gas from CO2-intensive industries (i.e. 100% CO2): i) screening of technologies (4 options for cultivation, 3 for culture dewatering, 3 for cell disruption, 4 for lipids e

  13. Orthogonal Design Method for Screening of Extraction Process of Keganyu Capsule%评《硫酸软骨素》一书

    Institute of Scientific and Technical Information of China (English)

    张岫美

    2012-01-01

    Objective To screen the optimal extraction conditions for Keganyu Capsule and ensure energy-saving production process and environmental protection. Methods With the content of chlorogenic acid as the index, the optimal extraction process was selected by investigating three main influential factors of water volume, decocting time and alcohol concentration with an L9(34) orthogonal test. Results The optimal extraction process was as follows: extracting twice with water, 10 times of amount of water for 2 h each time, 70% alcohol. Conclusion This process can be suitable for the industrialized production because it is reasonable, reliable, and has simple operation, low cost, as well as less emission pollutants.

  14. Fabrication of Non-instrumented capsule for DUPIC simulated fuel irradiation test in HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Kim, B.G.; Kang, Y.H.; Park, S.J.; Shin, Y.T. [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-10-01

    In order to develope DUPIC nuclear fuel, the irradiation test for simulated DUPIC fuel was planed using a non-instrumented capsule in HANARO. Because DUPIC fuel is highly radioactive material the non-instrumented capsule for an irradiation test of simulated DUPIC fuel in HANARO was designed to remotely assemble and disassemble in hot cell. And then, according to the design requirements the non-instrumented DUPIC capsule was successfully manufactured. Also, the manufacturing technologies of the non-instrumented capsule for irradiating the nuclear fuel in HANARO were established, and the basic technology for the development of the instrumented capsule technology was accumulated. This report describes the manufacturing of the non-instrumented capsule for simulated DUPIC fuel. And, this report will be based to develope the instrumented capsule, which will be utilized to irradiate the nuclear fuel in HANARO. 26 refs., 4 figs. (Author)

  15. Design and parametric optimization of thermal management of lithium-ion battery module with reciprocating air-flow

    Institute of Scientific and Technical Information of China (English)

    刘燕平; 欧阳陈志; 江清柏; 梁波

    2015-01-01

    Single cell temperature difference of lithium-ion battery (LIB) module will significantly affect the safety and cycle life of the battery. The reciprocating air-flow module created by a periodic reversal of the air flow was investigated in an effort to mitigate the inherent temperature gradient problem of the conventional battery system with a unidirectional coolant flow with computational fluid dynamics (CFD). Orthogonal experiment and optimization design method based on computational fluid dynamics virtual experiments were developed. A set of optimized design factors for the cooling of reciprocating air flow of LIB thermal management was determined. The simulation experiments show that the reciprocating flow can achieve good heat dissipation, reduce the temperature difference, improve the temperature homogeneity and effectively lower the maximal temperature of the modular battery. The reciprocating flow improves the safety, long-term performance and life span of LIB.

  16. Design and parametric study on energy harvesting from bridge vibration using tuned dual-mass damper systems

    Science.gov (United States)

    Takeya, Kouichi; Sasaki, Eiichi; Kobayashi, Yusuke

    2016-01-01

    A bridge vibration energy harvester has been proposed in this paper using a tuned dual-mass damper system, named hereafter Tuned Mass Generator (TMG). A linear electromagnetic transducer has been applied to harvest and make use of the unused reserve of energy the aforementioned damper system absorbs. The benefits of using dual-mass systems over single-mass systems for power generation have been clarified according to the theory of vibrations. TMG parameters have been determined considering multi-domain parameters, and TMG has been tuned using a newly proposed parameter design method. Theoretical analysis results have shown that for effective energy harvesting, it is essential that TMG has robustness against uncertainties in bridge vibrations and tuning errors, and the proposed parameter design method for TMG has demonstrated this feature.

  17. Implementing a parametric maximum flow algorithm for optimal open pit mine design under uncertain supply and demand

    OpenAIRE

    M W A Asad; R Dimitrakopoulos

    2013-01-01

    Conventional open pit mine optimization models for designing mining phases and ultimate pit limit do not consider expected variations and uncertainty in metal content available in a mineral deposit (supply) and commodity prices (market demand). Unlike the conventional approach, a stochastic framework relies on multiple realizations of the input data so as to account for uncertainty in metal content and financial parameters, reflecting potential supply and demand. This paper presents a new met...

  18. Analysis of non-typeable Haemophilus influenzae in invasive disease reveals lack of the capsule locus.

    Science.gov (United States)

    Lâm, T-T; Claus, H; Frosch, M; Vogel, U

    2016-01-01

    Among invasive Haemophilus influenzae, unencapsulated strains have largely surpassed the previously predominant serotype b (Hib) because of Hib vaccination. Isolates without the genomic capsule (cap) locus are designated non-typeable H. influenzae (NTHi). They are different from capsule-deficient variants that show deletion of the capsule transport gene bexA within the cap locus. The frequency of capsule-deficient variants in invasive disease is unknown. We analysed 783 unencapsulated invasive isolates collected over 5 years in Germany and found no single capsule-deficient isolate. Invasive unencapsulated strains in Germany were exclusively NTHi. A negative serotyping result by slide agglutination was therefore highly predictive for NTHi.

  19. Hybrid Integration of Taguchi Parametric Design, Grey Relational Analysis, and Principal Component Analysis Optimization for Plastic Gear Production

    Directory of Open Access Journals (Sweden)

    Nik Mizamzul Mehat

    2014-01-01

    Full Text Available The identification of optimal processing parameters is an important practice in the plastic injection moulding industry because of the significant effect of such parameters on plastic part quality and cost. However, the optimization design of injection moulding process parameters can be difficult because more than one quality characteristic is used in the evaluation. This study systematically develops a hybrid optimization method for multiple quality characteristics by integrating the Taguchi parameter design, grey relational analysis, and principal component analysis. A plastic gear is used to demonstrate the efficiency and validity of the proposed hybrid optimization method in controlling all influential injection moulding processing parameters during plastic gear manufacturing. To minimize the shrinkage behaviour in tooth thickness, addendum circle, and dedendum circle of moulded gear, the optimal combination of different process parameters is determined. The case study demonstrates that the proposed optimization method can produce plastic-moulded gear with minimum shrinkage behaviour of 1.8%, 1.53%, and 2.42% in tooth thickness, addendum circle, and dedendum circle, respectively; these values are less than the values in the main experiment. Therefore, shrinkage-related defects that lead to severe failure in plastic gears can be effectively minimized while satisfying the demand of the global plastic gear industry.

  20. Capsule endoscopy in celiac disease

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Video capsule endoscopy is an attractive and patient- friendly tool that provides high quality images of the small bowel. Obscure gastrointestinal bleeding is the primary and most evaluated indication to capsule endoscopy; however, indications are expanding and a small number of preliminary reports have been presented concerning the role of video capsule endoscopy in the diagnosis of celiac disease. The purpose of this review is to update the current knowledge and to hypothesize on future perspectives of the use of video capsule endoscopy in patients with celiac disease.

  1. Design of digital parametric equalizer based on function prototype%基于原型法的数字参量均衡器设计

    Institute of Scientific and Technical Information of China (English)

    蒋伟峰; 刘济林; 王兴国

    2001-01-01

    在音频处理中,均衡器可以改变音频信号的频响特性,它是由多个峰值滤波器组成的,并且它要求每个滤波器的通带可在0dB上下变化,以实现系统的滤波特性,如通过在整个频段中的某几个频段进行提升或削减一定的分贝数,以达到满意的听觉效果。由于参量均衡器对滤波器的频响要求及参数调节方法有其特殊性,因此它的设计方法也有其自身的特点。采用双二阶函数作为滤波器的原型函数,通过简单的双线性变换,得到数字参量均衡器的各个系数。在实际应用中这些系数可以在事先计算好,需要时将它们加载到DSP中去。%In audio signal processing, equalizer can adjust the responsecharacteristic of amplitude to frequency of audio signal, equalizer consists of multiple bandpass filters. The passband of each filter of equalizers can be varied about the 0 dB level ,thereby realizing a filter system capable of boosting or cutting an input signal at the prescribed decibel within multiple frequency bands, therefore, a good effect will be produced. The design of parametric equalizer has its peculiarity because of its particular amplitude to frequency feature and its parameters adjustment way. Analyzing the characteristics of biquadratic function, a biquadratic function acted as peak-filter prototype, we apply a bilinear transformation to it, and then get all coefficients of digital parametric equalizers. In practical application, these coefficients can be calculated in advance, and can be download to DSP in demand.

  2. 3-D finite element stress analysis for fatigue design and evaluation: a parametric study of MOV(Motor Operated Valve)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyeong Keun; Lee, Sang Min; Chang, Yoon Suk; Choi, Jae Boong; Kim, Young Jin [Sungkyunkwan Univ., Suwon (Korea, Republic of); Kim, Yun Jae [Korea Univ., Seoul (Korea, Republic of)

    2004-07-01

    In this paper, a new procedure is proposed to accomplish the primary plus secondary stress(P+Q) at the 'structural element' instead of 'transition element'. For the P+Q evaluation, the calculated stresses by FEA are linearized along a stress classification line to extract the stress category, then the stress intensity is calculated to compare with the 3Sm limit. Also, in this paper, the 'design by analysis' criteria, adopted fundamental concepts and a new approach to calculate Ke factors are explained. The new procedure combined with 3-D FEA has been applied to motor operated valve in order to the over conservatism and the rack of margin. The evaluation results show a good applicability and can be utilized for fatigue life evaluation by using P+Q.

  3. On Parametric Design of Computer Chassis Components Based on Pro/Toolkit%基于 Pro/Toolkit 的专用计算机机箱零部件参数化设计的研究

    Institute of Scientific and Technical Information of China (English)

    刘晓雯

    2015-01-01

    The author of this paper,who has conducted a parametric design of computer chassis components with Pro/Toolkit of Pro/E,describes the basic steps and key technologies involved, and demonstrate that the software development kit of three-dimensional design software can be employed for the parametric design of component parameters.%利用 Pro/E 的二次开发工具 Pro/Toolkit 对专用计算机机箱零部件进行了参数化设计,阐述了基本步骤和关键技术,说明基于三维设计软件的二次开发功能可以很好地实现产品零部件的参数化设计。

  4. The use of design-of-experiments methodology to optimize polymer capsule fabrication. 1998 summer research program for high school juniors at the University of Rochester`s Laboratory for Laser Energetics: Student research reports

    Energy Technology Data Exchange (ETDEWEB)

    Lai, L. [Pittsford Mendon High School, NY (United States)

    1999-03-01

    Future inertial-fusion experiments on Omega will utilize {approximately} 1 mm-diameter cryogenic targets that have a {approximately} 100-{micro}m-thick, uniformly-frozen fuel layer on their interior. It is desired that they have a stress-free wall thickness < 1 {micro}m and an rms surface roughness < 20 nm. A design-of-experiments (DOE) approach was used to characterize a glow-discharge-polymerization coater built at LLE to fabricate smooth, stress-free capsules with submicron wall thicknesses. The DOE approach was selected because several parameters can be changed simultaneously in a manner which allows the minimum number of runs to be performed to obtain statistically-relevant data. Planar, silicon substrates were coated with {approximately} 3--5 {micro}m of polymer and profilometry was used to determine the coating rate, the film stress, and the surface roughness. The coating rate was found to depend on the trans-2-butene/hydrogen ratio, the total gas-flow rate, the total chamber pressure, and the RF power. In addition, a two-parameter interaction between the total pressure and the RF power also affects the coating rate. The film stress depends on the total chamber pressure and the total mass-flow rate. The surface roughness is independent of the parameters studied. Preliminary results indicate that capsules can be produced rapidly without affecting the smoothness of their outside surface and without residual stress in their walls.

  5. Design and Development of Intracavity Optical Parametric Oscillator-based Eye Safe Laser Operating at 20 Hz without Forced Air Cooling

    Directory of Open Access Journals (Sweden)

    Atul Bhardwaj

    2013-12-01

    Full Text Available In this paper we report the design and development of an electro-optically Q-switched diode pumped Nd:YAG laser with intracavity optical parametric oscillator, generating ~ 5 ns laser pulses of ~8 mJ energy at eye safe wavelength of 1534 nm. A Z-shaped laser resonator has been designed with porro prism end reflector in Q-switch arm containing RTP Q-Switch and a suitably oriented waveplate. The gain arm consists of a Ø3 x 72 mm Nd: YAG laser rod, pumped from one side by 3 x 5 bar laser diode array stack emitting total optical peak power of 740 W at 804 nm at 38 °C. Thermoelectric coolers (TECs have been employed to maintain the optimum temperature of laser diode arrays and the combined heat load from the pump chamber and TECs is distributed over the system base plate with embedded heat pipes. Such cooling mechanism has eliminated the requirement of fins and fans in the laser system. Eye safe radiation is out-coupled through intra cavity KTA OPO (5 x 5 x 20 mm3 placed in the gain arm. Laser was operated at 20 Hz for several duty cycles of 10 min on and 10 min off and output energy remained stable within ±0.5 mJ without any forced air/liquid cooling.Defence Science Journal, 2013, 63(6, pp.599-605, DOI:http://dx.doi.org/10.14429/dsj.63.5759

  6. Research on the Process of Parametric Design Based on Pro/TOOLKIT Software%基于Pro/TOOLKIT的Pro/E参数化设计

    Institute of Scientific and Technical Information of China (English)

    刘文强; 胡夏夏; 宋士刚

    2011-01-01

    Pro/E is one of the most wide-used software which has the strong 3d modeling and simulation analysis and so on. Aiming at the general machinery and standard parts which are the same except the dimensions, Pro/E provides an API-Pro/TOOLKIT to shorten the time of designing. This paper was about the compile of the source file, through dynamic link store the compile and connection of the program, the registeration and run of the program by Visual C + + and Pro/ TOOLKIT through DLL, and it also described the whole process of the parametric design, finally an example was given out to prove the method. [ Ch,4 fig. 10 ref. ]%Pro/E是应用非常广的一款软件,它提供了强大的三维造型、模拟分析等能力,并针对结构基本相同、只是尺寸有所差别的通用机械和标准零件等,Pro/E开发了Pro/TOOLKIT这一客户化开发工具包,以节省逐一进行建模所浪费的大量时间.文章利用VC++和Pro/TOOLKIT,通过动态链接库方式,完成源文件的编写、程序的编译和连接以及程序的注册和运行,详尽叙述了整个参数化的设计过程,并最后以1个实例进行了验证.

  7. Magnetism in metal-organic capsules

    Energy Technology Data Exchange (ETDEWEB)

    Atwood, Jerry L.; Brechin, Euan K; Dalgarno, Scott J.; Inglis, Ross; Jones, Leigh F.; Mossine, Andrew; Paterson, Martin J.; Power, Nicholas P.; Teat, Simon J.

    2010-01-07

    Nickel and cobalt seamed metal-organic capsules have been isolated and studied using structural, magnetic and computational approaches. Antiferromagnetic exchange in the Ni capsule results from coordination environments enforced by the capsule framework.

  8. Patency(C) and agile(C) capsules

    Institute of Scientific and Technical Information of China (English)

    àngel Caunedo-àlvarez; Javier Romero-Vazquez; Juan M Herrerias-Gutierrez

    2008-01-01

    Small bowel strictures can be missed by current diagnostic methods.The Patency capsule is a new non-endoscopic dissolvable capsule which has as an objective of checking the patency of digestive tract,in a non-invasive manner.The available clinical trials have demonstrated that the Patency(C) capsule is a good tool for assessment of the functional patency of the small bowel,and it allows identification of those patients who can safely undergo a capsule endoscopy,despite clinical and radiographic evidence of small-bowel obstruction.Some cases of intestinal occlusion have been reported with the Patency(C) capsule,four of them needed surgery.So,a new capsule with two timer plugs (Agile(C) capsule) has been recently developed in order to minimize the risk of occlusion.This new device stars its dissolution process earlier (30 h after ingestion) and its two timer plugs have been designed to begin the disintegration even when the device is blocked in a tight stricture.

  9. Controlling Parametric Resonance

    DEFF Research Database (Denmark)

    Galeazzi, Roberto; Pettersen, Kristin Ytterstad

    2012-01-01

    Parametric resonance is a resonant phenomenon which takes place in systems characterized by periodic variations of some parameters. While seen as a threatening condition, whose onset can drive a system into instability, this chapter advocates that parametric resonance may become an advantage if t...

  10. Parametric Mass Reliability Study

    Science.gov (United States)

    Holt, James P.

    2014-01-01

    The International Space Station (ISS) systems are designed based upon having redundant systems with replaceable orbital replacement units (ORUs). These ORUs are designed to be swapped out fairly quickly, but some are very large, and some are made up of many components. When an ORU fails, it is replaced on orbit with a spare; the failed unit is sometimes returned to Earth to be serviced and re-launched. Such a system is not feasible for a 500+ day long-duration mission beyond low Earth orbit. The components that make up these ORUs have mixed reliabilities. Components that make up the most mass-such as computer housings, pump casings, and the silicon board of PCBs-typically are the most reliable. Meanwhile components that tend to fail the earliest-such as seals or gaskets-typically have a small mass. To better understand the problem, my project is to create a parametric model that relates both the mass of ORUs to reliability, as well as the mass of ORU subcomponents to reliability.

  11. Pentagonal shaped microstrip patch antenna in wireless capsule endoscopy system

    Directory of Open Access Journals (Sweden)

    Bondili Kohitha Bai

    2012-01-01

    Full Text Available Wireless capsule endoscopy is a best option for exploring inaccessible areas of small intestine for inspection of gastrointestinal tract. This technique brings less pain compare to conventional endoscopy technique. The wireless endoscopy system comprises of three main modules: an ingestible capsule that is swallowed by the patient, an external control unit and display device for image display. In this paper we proposed pentagonal shape microstrip patch antenna for wireless capsule endoscopy system. Inhibiting characteristics of a single microstrip patch like low gain, light weight, thin thickness and smaller bandwidth, make it more popular. This kind of antenna is aggressive miniaturized to meet the requirements of the wireless capsule endoscope. The simulation results show that the designed Circular Polarization (CP pentagonal shaped microstrip patch antenna gives axial ratio of 0.6023 at 2.38 GHz and CP axial ratio bandwidth of 36MHz with 1.5%. The antenna designed for wireless capsule endoscopy is a proposed one, which may work effectively when compared to other antennas in the capsule.

  12. The Exploration on the Feng Shuey Philosophy of Parametric Architectural Design%探究参数化建筑设计中所蕴藏的风水哲理

    Institute of Scientific and Technical Information of China (English)

    张硕; 王丽

    2014-01-01

    Author studies on feng shuey philosophy of para-metric architectural design, taking galaxy SOHO and CCTV new building as examples to il ustrate that the feng shuey cu-lture which has been passed down for thousand years must have it’s value of spread and that parametric architectural also wil be dif icult to get the inheritance of history out of the feng shuey philosophy.%笔者就参数化建筑中所蕴藏的风水哲理进行探讨,以银河SOHO和央视新大楼为例意在阐明在中国流传了千年之久的风水文化必有其传播价值,并且脱离了风水的参数化建筑也将很难得到历史的传承。

  13. The study of Parametric Design for Body of Organization based on Skeleton Model by Pro/E%曲柄摇杆机构的骨架模型法参数化设计研究

    Institute of Scientific and Technical Information of China (English)

    李润

    2012-01-01

    The top- down design mode accords with the design process for product. The skeleton model design is one of the method that top - down designs in pro/E. The skeleton model of Pro/E reflects the total structure and design project of product. The skeleton model promises scientific product design and the accuracy of assemble. With Pro/Engineer parametric design, a new method of skeleton model for body of organization is proposed. By skeleton model method, the parts of organization body is designed. The Parametric designs and the series designs is finished with change of the parameter of skeleton model. This system provides a simple and convenient modeling method, which is helpful to improve the designing quality and working efficiency and shorten the design cycle. The model can be applied to other similar parts of the design process.%自顶向下的设计模式符合产品的设计思路,Pro/E软件在组件模式下的骨架模型设计是自顶向下设计的方法之一。该法可以使设计信息在整个组件中顺利地传达,保证了产品设计合理性和装配的准确性,从而确保稳妥的设计。结合Pro/E参数化建模思路,在组件模式下设计了曲柄摇杆机构的参数化骨架模型,并通过该骨架模型创建了机构零件,通过改变机构骨架模型参数,实现了曲柄摇杆机构的参数化和系列化设计。

  14. 基于Pro/E的齿轮减速器参数化系统设计%The design of three-dimension parametric system for reducer based on Pro/E

    Institute of Scientific and Technical Information of China (English)

    韩衍昭; 刘爱敏; 于丽虹

    2012-01-01

    减速器产品的系列化和相似性程度很高,为提高设计效率和质量,开发系列化产品的三维参数化系统显得尤为必要.在充分利用Pro/E强大的三维处理功能及参数化设计的基础上而研究的,结合二次开发工具Pro/TOOLKIT,利用Visual C++做为计算机开发工具,采用模块化设计思想,实现了减速器系列产品各零部件的三维参数化设计和虚拟装配.该系统的开发在缩短产品设计周期、提高工作效率方面有显著的作用,对减速器系列化产品的设计开发工作有普遍的适应性和扩展性.%The similarity and serial of reducer are very high.Developing the three-dimension parametric system for serial production is very necessary in order to improve the design efficiency and quality. By fully used the three-dimensional function and parametric design of Pro/E and Visual C++ as computer development tool,based on Pro/TOOLKIT tool and the principle of modular design,it has realized the parametric design and virtual assembly of gear reducer's component.This system had notable role on shortening the period of products plan and raising working efficiency,which would have universal adaptability and development for the serial product of gear reducer.

  15. Synchronization of chaos in non-identical parametrically excited systems

    Energy Technology Data Exchange (ETDEWEB)

    Idowu, B.A. [Department of Physics, Lagos State University, Ojo (Nigeria)], E-mail: babaidowu@yahoo.com; Vincent, U.E. [Department of Physics, Olabisi Onabanjo University, P.M.B 2002, Ago-Iwoye (Nigeria)], E-mail: ue_vincent@yahoo.com; Njah, A.N. [Department of Physics, University of Agriculture, Abeokuta (Nigeria)

    2009-03-15

    In this paper, we investigate the synchronization of chaotic systems consisting of non-identical parametrically excited oscillators. The active control technique is employed to design control functions based on Lyapunov stability theory and Routh-Hurwitz criteria so as to achieve global chaos synchronization between a parametrically excited gyroscope and each of the parametrically excited pendulum and Duffing oscillator. Numerical simulations are implemented to verify the results.

  16. 矩阵二阶线性系统的观测器设计:一种参数化方法%Observer design for matrix second-order linear systems:a parametric approach

    Institute of Scientific and Technical Information of China (English)

    武云丽; 段广仁

    2004-01-01

    The issue of designing a type of generalized Luenberger observers for matrix secondorder linear (MSOL) systems was addressed in the matrix second-order framework. By introducing the concept of stable matrix pair for MSOL systems, sufficient and necessary conditions for the design of the type of generalized Luenberger observers were given under the assumption of controllability and observability of the MSOL system. Based on the proposed conditions and the right coprime factorization of the system, a parametric approach to the design of such type of observers was presented. The proposed approach provides all the degrees of design freedom, which can be further utilized to achieve additional system specifications. A spring-mass system was utilized to show the effect of the proposed method.

  17. About Bifurcational Parametric Simplification

    CERN Document Server

    Gol'dshtein, V; Yablonsky, G

    2015-01-01

    A concept of "critical" simplification was proposed by Yablonsky and Lazman in 1996 for the oxidation of carbon monoxide over a platinum catalyst using a Langmuir-Hinshelwood mechanism. The main observation was a simplification of the mechanism at ignition and extinction points. The critical simplification is an example of a much more general phenomenon that we call \\emph{a bifurcational parametric simplification}. Ignition and extinction points are points of equilibrium multiplicity bifurcations, i.e., they are points of a corresponding bifurcation set for parameters. Any bifurcation produces a dependence between system parameters. This is a mathematical explanation and/or justification of the "parametric simplification". It leads us to a conjecture that "maximal bifurcational parametric simplification" corresponds to the "maximal bifurcation complexity." This conjecture can have practical applications for experimental study, because at points of "maximal bifurcation complexity" the number of independent sys...

  18. Parametric Conversion Using Custom MOS Varactors

    Directory of Open Access Journals (Sweden)

    Iniewski Krzysztof (Kris

    2006-01-01

    Full Text Available The possible role of customized MOS varactors in amplification, mixing, and frequency control of future millimeter wave CMOS RFICs is outlined. First, the parametric conversion concept is revisited and discussed in terms of modern RF communications systems. Second, the modeling, design, and optimization of MOS varactors are reconsidered in the context of their central role in parametric circuits. Third, a balanced varactor structure is proposed for robust oscillator frequency control in the presence of large extrinsic noise expected in tightly integrated wireless communicators. Main points include the proposal of a subharmonic pumping scheme based on the MOS varactor, a nonequilibrium elastance-voltage model, optimal varactor layout suggestions, custom m-CMOS varactor design and measurement, device-level balanced varactor simulations, and parametric circuit evaluation based on measured device characteristics.

  19. DWPF Welder Parametric Study

    Energy Technology Data Exchange (ETDEWEB)

    Plodinec, M.J.

    1998-11-20

    After being filled with glass, DWPF canistered waste forms will be welded closed using an upset resistance welding process. This final closure weld must be leaktight, and must remain so during extended storage at SRS. As part of the DWPF Startup Test Program, a parametric study (DWPF-WP-24) has been performed to determine a range of welder operating parameters which will produce acceptable welds. The parametric window of acceptable welds defined by this study is 90,000 + 15,000 lb of force, 248,000 + 22,000 amps of current, and 95 + 15 cycles* for the time of application of the current.

  20. Controlling the dynamic range of a Josephson parametric amplifier

    Energy Technology Data Exchange (ETDEWEB)

    Eichler, Christopher; Wallraff, Andreas [ETH Zuerich, Department of Physics, Zuerich (Switzerland)

    2014-12-01

    One of the central challenges in the development of parametric amplifiers is the control of the dynamic range relative to its gain and bandwidth, which typically limits quantum limited amplification to signals which contain only a few photons per inverse bandwidth. Here, we discuss the control of the dynamic range of Josephson parametric amplifiers by using Josephson junction arrays. We discuss gain, bandwidth, noise, and dynamic range properties of both a transmission line and a lumped element based parametric amplifier. Based on these investigations we derive useful design criteria, which may find broad application in the development of practical parametric amplifiers. (orig.)

  1. Inductive-Based Wireless Power Recharging System for an Innovative Endoscopic Capsule

    Directory of Open Access Journals (Sweden)

    Giuseppe Tortora

    2015-09-01

    Full Text Available Wireless capsule endoscopic devices are adopted for painless diagnosis of cancer and other diseases affecting the gastrointestinal tract as an alternative to traditional endoscopy. Although much work has been done to improve capsule performance in terms of active navigation, a major drawback is the limited available energy on board the capsule, usually provided by a battery. Another key shortcoming of active capsules is their limitation in terms of active functionalities and related costs. An inductive-based wireless recharging system for the development of an innovative capsule for colonoscopy is proposed in this paper; the aim is to provide fast off-line battery recovery for improving capsule lifecycle and thus reducing the cost of a single endoscopic procedure. The wireless recharging system has been properly designed to fit the dimensions of a capsule for colonoscopy but it can be applied to any biomedical devices to increase the number of times it can be used after proper sterilization. The current system is able to provide about 1 W power and is able to recharge the battery capsule in 20 min which is a reasonable time considering capsule operation time (10–15 min.

  2. Simulations of indirectly driven gas-filled capsules at the National Ignition Facility

    Energy Technology Data Exchange (ETDEWEB)

    Weber, S. V.; Casey, D. T.; Eder, D. C.; Pino, J. E.; Smalyuk, V. A.; Remington, B. A.; Rowley, D. P.; Yeamans, C. B.; Tipton, R. E.; Barrios, M.; Benedetti, R.; Berzak Hopkins, L.; Bleuel, D. L.; Bond, E. J.; Bradley, D. K.; Caggiano, J. A.; Callahan, D. A.; Cerjan, C. J.; Clark, D. S.; Divol, L. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); and others

    2014-11-15

    Gas-filled capsules imploded with indirect drive on the National Ignition Facility have been employed as symmetry surrogates for cryogenic-layered ignition capsules and to explore interfacial mix. Plastic capsules containing deuterated layers and filled with tritium gas provide a direct measure of mix of ablator into the gas fuel. Other plastic capsules have employed DT or D{sup 3}He gas fill. We present the results of two-dimensional simulations of gas-filled capsule implosions with known degradation sources represented as in modeling of inertial confinement fusion ignition designs; these are time-dependent drive asymmetry, the capsule support tent, roughness at material interfaces, and prescribed gas-ablator interface mix. Unlike the case of cryogenic-layered implosions, many observables of gas-filled implosions are in reasonable agreement with predictions of these simulations. Yields of TT and DT neutrons as well as other x-ray and nuclear diagnostics are matched for CD-layered implosions. Yields of DT-filled capsules are over-predicted by factors of 1.4–2, while D{sup 3}He capsule yields are matched, as well as other metrics for both capsule types.

  3. Capsule endoscopy of the esophagus.

    Science.gov (United States)

    Waterman, Matti; Gralnek, Ian M

    2009-08-01

    Video capsule endoscopy has acquired wide clinical acceptance since its the US Food and Drug Administration approval in 2001. Recently, the technology of video capsule endoscopy has been adapted to other organs in the gastrointestinal tract, including the esophagus and colon. In this review, we discuss esophageal capsule endoscopy (ECE)-the procedure, its indications, contraindications, safety, and future applications. ECE is a minimally invasive procedure that uses special video capsules with ability to acquire images from 2 cameras with high image storing speed of 14 to 18 frames per second. A special ingestion procedure allows for prolonged esophageal transit time and an optimized view of the gastroesophageal junction. ECE has been shown to have moderately high sensitivity and accuracy in the diagnosis and surveillance of Barrett esophagus in patients with gastroesophageal reflux disease but has not demonstrated superiority to esogastroduodenoscopy in cost-effectiveness models. In patients with portal hypertension, ECE has a sensitivity of 63% to 100% for screening of esophageal varices, but does not seem to be superior to esogastroduodenoscopy in its cost-effectiveness. No serious complications have been reported after ECE although a low rate of esophageal capsule retention (0.7% to 2.2%) has been reported, usually because of unsuspected esophageal strictures. Contraindications to capsule endoscopy include known or suspected gastrointestinal and esophageal obstruction, strictures, or fistulas, intestinal pseudoobstruction, and children under 10 years of age. It is expected that improvements in imaging technology will improve the accuracy of ECE with the development of immunological-based and chemical-based diagnostic capabilities.

  4. Capsule endoscopy in neoplastic diseases

    Institute of Scientific and Technical Information of China (English)

    Marco Pennazio; Emanuele Rondonotti; Roberto de Franchis

    2008-01-01

    Until recently,diagnosis and management of small-bowel tumors were delayed by the difficulty of access to the small bowel and the poor diagnostic capabilities of the available diagnostic techniques.An array of new methods has recently been developed,increasing the possibility of detecting these tumors at an earlier stage.Capsule endoscopy (CE) appears to be an ideal tool to recognize the presence of neoplastic lesions along this organ,since it is non-invasive and enables the entire small bowel to be visualized.Highquality images of the small-bowel mucosa may be captured and small and fiat lesions recognized,without exposure to radiation.Recent studies on a large population of patients undergoing CE have reported small-bowel tumor frequency only slightly above that reported in previous surgical series (range,1.6%-2.4%)and have also confirmed that the main clinical indication to CE in patients with small-bowel tumors is obscure gastrointestinal (GI) bleeding.The majority of tumors identified by CE are malignant;many were unsuspected and not found by other methods.However,it remains difficult to identify pathology and tumor type based on the lesion's endoscopic appearance.Despite its limitations,CE provides crucial information leading in most cases to changes in subsequent patient management.Whether the use of CE in combination with other new diagnostic (MRI or multidetector CT enterography) and therapeutic (Push-and-pull enteroscopy) techniques will lead to earlier diagnosis and treatment of these neoplasms,ultimately resulting in a survival advantage and in cost savings,remains to be determined through carefully-designed studies.

  5. The Design of pH Measuring Module in the Smart Capsule for Drug Delivery System*%智能释药胶囊内酸碱度测量模块的设计

    Institute of Scientific and Technical Information of China (English)

    李晓华; 刘洪英; 贾子如; 皮喜田; 郑小林; 彭承琳; 温志渝

    2011-01-01

    A smart capsule for drug delivery based on a pH sensor was proposed here. The system can automatically identify the pH changes of the gastrointestinal (GI) tract, and then it can automatically release the drug if the pH changes satisfy the established procedure. A pH measuring module in this system was designed here. The pH measuring module consists of pH sensor module, measuring circuit module, microprocessor chip module, and power management module. The performances of pH measuring module and pH sensors were tested in vitro experiments. The experimental results showed that the sensitivity of pH sensor was 43.5 mV/pH, which met the need of pH measuring in the GI tract. Additionally,when the trigger voltage stored in the micro controller unit( MCU)was from 113.1 to 282.8 mV, the capsule could release the medicine in the esophagus, stomach and intestinal tract accurately according to the change of pH value.%提出了一种能够根据消化道中pH值的变化而自动释药的智能释药电子胶囊,设计了基于pH传感器的酸碱度测量模块.酸碱度测量模块包括pH传感器模块、测量电路模块、微处理器芯片模块和电源管理模块.在离体状态下对pH传感器进行了原理性实验,并对酸碱度模块的性能进行了测试.实验结果表明pH传感器的灵敏度为43.5 mV/pH,满足消化道内pH值测量的需要,得出单片机程序中的触发电压范围为113.1~282.8 mV,通过pH值变化的测定,可以准确的在食道,胃部,和肠部三个区域内进行释药.

  6. Multiple Frequency Parametric Sonar

    Science.gov (United States)

    2015-09-28

    300003 1 MULTIPLE FREQUENCY PARAMETRIC SONAR STATEMENT OF GOVERNMENT INTEREST [0001] The invention described herein may be manufactured and...beams. However, the multiple nonlinear interactions are not taken advantage of in order to generate additional efficiencies, bandwidth, and SNR...array. [0050] It will be understood that many additional changes in details, materials , steps, and arrangements of parts which have been described

  7. Parametric Differentiation and Integration

    Science.gov (United States)

    Chen, Hongwei

    2009-01-01

    Parametric differentiation and integration under the integral sign constitutes a powerful technique for calculating integrals. However, this topic is generally not included in the undergraduate mathematics curriculum. In this note, we give a comprehensive review of this approach, and show how it can be systematically used to evaluate most of the…

  8. Ignition capsules with aerogel-supported liquid DT fuel for the National Ignition Facility

    Directory of Open Access Journals (Sweden)

    Ho D.D.-M.

    2013-11-01

    Full Text Available For high repetition-rate fusion power plant applications, capsules with aerogel-supported liquid DT fuel can have much reduced fill time compared to β-layering a solid DT fuel layer. The melting point of liquid DT can be lowered once liquid DT is embedded in an aerogel matrix, and the DT vapor density is consequently closer to the desired density for optimal capsule design requirement. We present design for NIF-scale aerogel-filled capsules based on 1-D and 2-D simulations. An optimal configuration is obtained when the outer radius is increased until the clean fuel fraction is within 65 – 75% at peak velocity. A scan (in ablator and fuel thickness parameter space is used to optimize the capsule configurations. The optimized aerogel-filled capsule has good low-mode robustness and acceptable high-mode mix.

  9. A THEORY FOR BROADBAND VARACTOR PARAMETRIC AMPLIFIERS

    Science.gov (United States)

    design and synthesis of broadband varactor parametric amplifiers. The circuit considered in this thesis is that of linear variable capacitors embedded...second and more important inherent property is that, due to the frequency-coupling action of the variable capacitor , the scattering coefficient at the

  10. Parametric Design Based on SolidWorks for Industrial Sewing Machine Casing%基于 SolidWorks 的工业平缝机机壳参数化设计

    Institute of Scientific and Technical Information of China (English)

    郭莹; 曹巨江; 张科宇

    2016-01-01

    以面向对象的VB 6.0为开发平台,结合Access建立的标准数据库,控制服务端SolidWorks二次开发接口的A PI函数,调用对象、属性、方法,实现对工业平缝机机壳参数化模块的二次开发。用该方法可以快速、准确、高效地设计出符合用户要求的工业平缝机机壳的三维模型。%The paper proposes a parametric design method of industrial sewing machine casing by use of SolidWorks .This method is based on the object-oriented VB language platform and the standard database established by Access ,to accomplish the secondary development of the parametric design module of the industrial sewing machine casing through controlling API function offered by secondary development interface of server SolidWorks and calling object ,attribute and method .The proposed method can quickly establish the three-dimensional model of the industrial sewing machine casing and it is accurate and efficient to meet the requirements of the user .

  11. Parametric Study Of Window Frame Geometry

    DEFF Research Database (Denmark)

    Zajas, Jan Jakub; Heiselberg, Per

    2013-01-01

    This paper describes a parametric study on window frame geometry with the goal of designing frames with very good thermal properties. Three different parametric frame models are introduced, deseribed by a number of variables. In the first part of the study, a process of sensitivity analysis is co...... energy gain factor and minimizing the material use. Since the objectives contradiet each other, it was found that it is not possible to identifY a single solution that satisfies all these goals. lnstead, a compromise between the objectives has to be found....

  12. Parametric Amplification For Detecting Weak Optical Signals

    Science.gov (United States)

    Hemmati, Hamid; Chen, Chien; Chakravarthi, Prakash

    1996-01-01

    Optical-communication receivers of proposed type implement high-sensitivity scheme of optical parametric amplification followed by direct detection for reception of extremely weak signals. Incorporates both optical parametric amplification and direct detection into optimized design enhancing effective signal-to-noise ratios during reception in photon-starved (photon-counting) regime. Eliminates need for complexity of heterodyne detection scheme and partly overcomes limitations imposed on older direct-detection schemes by noise generated in receivers and by limits on quantum efficiencies of photodetectors.

  13. Polarization effect in parametric amplifier

    Institute of Scientific and Technical Information of China (English)

    Junhe Zhou; Jianping Chen; Xinwan Li; Guiling Wu; Yiping Wang

    2005-01-01

    @@ Polarization effect in parametric amplifiers is studied. Coupled equations are derived from the basic propagation equations and numerical solutions are given for both one-wavelength-pump and two-wavelengthpump systems. Several parametric amplifiers driven by pumps at one wavelength and two wavelengths are analyzed and the polarization independent parametric amplifier is proposed.

  14. Heat Transfer Parametric System Identification

    Science.gov (United States)

    1993-06-01

    Transfer Parametric System Identification 6. AUTHOR(S Parker, Gregory K. 7. PERFORMING ORGANIZATION NAME(S) AND AOORESS(ES) 8. PERFORMING ORGANIZATION...distribution is unlimited. Heat Transfer Parametric System Identification by Gregory K. Parker Lieutenant, United States Navy BS., DeVry Institute of...Modeling Concept ........ ........... 3 2. Lumped Parameter Approach ...... ......... 4 3. Parametric System Identification ....... 4 B. BASIC MODELING

  15. Towards Stabilizing Parametric Active Contours

    DEFF Research Database (Denmark)

    Liu, Jinchao; Fan, Zhun; Olsen, Søren Ingvor;

    2014-01-01

    Numerical instability often occurs in evolving of parametric active contours. This is mainly due to the undesired change of parametrization during evolution. In this paper, we propose a new tangential diffusion term to compensate this undesired change. As a result, the parametrization will converge...

  16. SITE TECHNOLOGY CAPSULE: NOVOCS EVALUATION AT NAS NORTH ISLAND

    Science.gov (United States)

    This is a SITE Technology Capsule. The MACTEC, Inc. (MACTEC), NoVOCs(TM) in-well volatile organic compounds (VOC) stripping technology is an in-situ groundwater remediation technology designed for the cleanup of groundwater contaminated with VOCs. The NoVOCs(TM) technology was ev...

  17. Potential value of Cs-137 capsules

    Energy Technology Data Exchange (ETDEWEB)

    Bloomster, C.H.; Brown, D.R.; Bruno, G.A.; Hazelton, R.F.; Hendrickson, P.L.; Lezberg, A.J.; Tingey, G.L.; Wilfert, G.L.

    1985-04-01

    We determined the value of Cs-137 compared to Co-60 as a source for the irradiation of fruit (apples and cherries), pork and medical supplies. Cs-137, in the WESF capsule form, had a value of approximately $0.40/Ci as a substitute for Co-60 priced at approximately $1.00/Ci. The comparison was based on the available curies emitted from the surface of each capsule. We developed preliminary designs for fourteen irradiation facilities; seven were based on Co-60 and seven were based on Cs-137. These designs provided the basis for estimating capital and operating costs which, in turn, provided the basis for determining the value of Cs-137 relative to Co-60 in these applications. We evaluated the effect of the size of the irradiation facility on the value of Cs-137. The cost of irradiation is low compared to the value of the product. Irradiation of apples for disinfestation costs $.01 to .02 per pound. Irradiation for trichina-safe pork costs $.02 per pound. Irradiation of medical supplies for sterilization costs $.07 to .12 per pound. The cost of the irradiation source, either Co-60 or Cs-137, contributed only a minor amount to the total cost of irradiation, about 5% for the fruit and hog cases and about 20% for the medical supply cases. We analyzed the sensitivity of the irradiation costs and Cs-137 value to several key assumptions.

  18. Wzy-dependent bacterial capsules as potential drug targets.

    Science.gov (United States)

    Ericsson, Daniel J; Standish, Alistair; Kobe, Bostjan; Morona, Renato

    2012-10-01

    The bacterial capsule is a recognized virulence factor in pathogenic bacteria. It likely works as an antiphagocytic barrier by minimizing complement deposition on the bacterial surface. With the continual rise of bacterial pathogens resistant to multiple antibiotics, there is an increasing need for novel drugs. In the Wzy-dependent pathway, the biosynthesis of capsular polysaccharide (CPS) is regulated by a phosphoregulatory system, whose main components consist of bacterial-tyrosine kinases (BY-kinases) and their cognate phosphatases. The ability to regulate capsule biosynthesis has been shown to be vital for pathogenicity, because different stages of infection require a shift in capsule thickness, making the phosphoregulatory proteins suitable as drug targets. Here, we review the role of regulatory proteins focusing on Streptococcus pneumoniae, Staphylococcus aureus, and Escherichia coli and discuss their suitability as targets in structure-based drug design.

  19. Phase noise suppression through parametric filtering

    Science.gov (United States)

    Cassella, Cristian; Strachan, Scott; Shaw, Steven W.; Piazza, Gianluca

    2017-02-01

    In this work, we introduce and experimentally demonstrate a parametric phase noise suppression technique, which we call "parametric phase noise filtering." This technique is based on the use of a solid-state parametric amplifier operating in its instability region and included in a non-autonomous feedback loop connected at the output of a noisy oscillator. We demonstrate that such a system behaves as a parametrically driven Duffing resonator and can operate at special points where it becomes largely immune to the phase fluctuations that affect the oscillator output signal. A prototype of a parametric phase noise filter (PFIL) was designed and fabricated to operate in the very-high-frequency range. The PFIL prototype allowed us to significantly reduce the phase noise at the output of a commercial signal generator operating around 220 MHz. Noise reduction of 16 dB (40×) and 13 dB (20×) were obtained, respectively, at 1 and 10 kHz offsets from the carrier frequency. The demonstration of this phase noise suppression technique opens up scenarios in the development of passive and low-cost phase noise cancellation circuits for any application demanding high quality frequency generation.

  20. Parametric modelling of a knee joint prosthesis.

    Science.gov (United States)

    Khoo, L P; Goh, J C; Chow, S L

    1993-01-01

    This paper presents an approach for the establishment of a parametric model of knee joint prosthesis. Four different sizes of a commercial prosthesis are used as an example in the study. A reverse engineering technique was employed to reconstruct the prosthesis on CATIA, a CAD (computer aided design) system. Parametric models were established as a result of the analysis. Using the parametric model established and the knee data obtained from a clinical study on 21 pairs of cadaveric Asian knees, the development of a prototype prosthesis that suits a patient with a very small knee joint is presented. However, it was found that modification to certain parameters may be inevitable due to the uniqueness of the Asian knee. An avenue for rapid modelling and eventually economical production of a customized knee joint prosthesis for patients is proposed and discussed.

  1. Capsule endoscopy in pediatric patients

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Wireless capsule endoscope (WCE) for the investigation of the small bowel is an approved technique both in adults and children (more than 10 years old). The present review provides data on the indications, diagnostic yield, adverse events and limitations of the WCE technique in children and tries to predict the future of WCE usage in this population of patients.

  2. Photon Production Within Storage Capsules

    CERN Document Server

    Rittmann, P D

    2003-01-01

    This report provides tables and electronic worksheets that list the photon production rate within SrF2 and CsC1 storage capsules, particularly the continuous spectrum of bremsstrahlung photons from the slowing down of the emitted electrons (BREMCALC).

  3. Parametric Analog Signal Amplification Applied to Nanoscale CMOS Technologies

    CERN Document Server

    Oliveira, João P

    2012-01-01

    This book is dedicated to the analysis of parametric amplification with special emphasis on the MOS discrete-time implementation. This implementation is demonstrated by the presentation of several circuits where the MOS parametric amplifier cell is used: small gain amplifier, comparator with embedded pre-amplification, discrete-time mixer/IIR-Filter, and analog-to-digital converter (ADC).  Experimental results are shown to validate the overall design technique. Provides the complete theoretical analysis, supported by electrical simulations, of the parametric amplification technique in both continuous time and discrete time domains; Describes the design flow of an ADC fully based on discrete-time parametric amplification in CMOS technology; Presents a high speed time-interleaved pipeline ADC, based on parametric MOS amplification techniques described, complementing theory discussed with experimental results.

  4. First beryllium capsule implosions on the National Ignition Facility

    Science.gov (United States)

    Kline, J. L.; Yi, S. A.; Simakov, A. N.; Olson, R. E.; Wilson, D. C.; Kyrala, G. A.; Perry, T. S.; Batha, S. H.; Zylstra, A. B.; Dewald, E. L.; Tommasini, R.; Ralph, J. E.; Strozzi, D. J.; MacPhee, A. G.; Callahan, D. A.; Hinkel, D. E.; Hurricane, O. A.; Milovich, J. L.; Rygg, J. R.; Khan, S. F.; Haan, S. W.; Celliers, P. M.; Clark, D. S.; Hammel, B. A.; Kozioziemski, B.; Schneider, M. B.; Marinak, M. M.; Rinderknecht, H. G.; Robey, H. F.; Salmonson, J. D.; Patel, P. K.; Ma, T.; Edwards, M. J.; Stadermann, M.; Baxamusa, S.; Alford, C.; Wang, M.; Nikroo, A.; Rice, N.; Hoover, D.; Youngblood, K. P.; Xu, H.; Huang, H.; Sio, H.

    2016-05-01

    The first indirect drive implosion experiments using Beryllium (Be) capsules at the National Ignition Facility confirm the superior ablation properties and elucidate possible Be-ablator issues such as hohlraum filling by ablator material. Since the 1990s, Be has been the preferred Inertial Confinement Fusion (ICF) ablator because of its higher mass ablation rate compared to that of carbon-based ablators. This enables ICF target designs with higher implosion velocities at lower radiation temperatures and improved hydrodynamic stability through greater ablative stabilization. Recent experiments to demonstrate the viability of Be ablator target designs measured the backscattered laser energy, capsule implosion velocity, core implosion shape from self-emission, and in-flight capsule shape from backlit imaging. The laser backscatter is similar to that from comparable plastic (CH) targets under the same hohlraum conditions. Implosion velocity measurements from backlit streaked radiography show that laser energy coupling to the hohlraum wall is comparable to plastic ablators. The measured implosion shape indicates no significant reduction of laser energy from the inner laser cone beams reaching the hohlraum wall as compared with plastic and high-density carbon ablators. These results indicate that the high mass ablation rate for beryllium capsules does not significantly alter hohlraum energetics. In addition, these data, together with data for low fill-density hohlraum performance, indicate that laser power multipliers, required to reconcile simulations with experimental observations, are likely due to our limited understanding of the hohlraum rather than the capsule physics since similar multipliers are needed for both Be and CH capsules as seen in experiments.

  5. Interactive Dimensioning of Parametric Models

    KAUST Repository

    Kelly, T.

    2015-05-01

    We propose a solution for the dimensioning of parametric and procedural models. Dimensioning has long been a staple of technical drawings, and we present the first solution for interactive dimensioning: A dimension line positioning system that adapts to the view direction, given behavioral properties. After proposing a set of design principles for interactive dimensioning, we describe our solution consisting of the following major components. First, we describe how an author can specify the desired interactive behavior of a dimension line. Second, we propose a novel algorithm to place dimension lines at interactive speeds. Third, we introduce multiple extensions, including chained dimension lines, controls for different parameter types (e.g. discrete choices, angles), and the use of dimension lines for interactive editing. Our results show the use of dimension lines in an interactive parametric modeling environment for architectural, botanical, and mechanical models. © 2015 The Author(s) Computer Graphics Forum © 2015 The Eurographics Association and John Wiley & Sons Ltd. Published by John Wiley & Sons Ltd.

  6. Relational Parametricity for Computational Effects

    CERN Document Server

    Møgelberg, Rasmus Ejlers

    2009-01-01

    According to Strachey, a polymorphic program is parametric if it applies a uniform algorithm independently of the type instantiations at which it is applied. The notion of relational parametricity, introduced by Reynolds, is one possible mathematical formulation of this idea. Relational parametricity provides a powerful tool for establishing data abstraction properties, proving equivalences of datatypes, and establishing equalities of programs. Such properties have been well studied in a pure functional setting. Many programs, however, exhibit computational effects, and are not accounted for by the standard theory of relational parametricity. In this paper, we develop a foundational framework for extending the notion of relational parametricity to programming languages with effects.

  7. 卷烟包装设备专用零件参数化CAD系统开发%Development of a parametric designing CAD system for parts special for cigarette packing equipment

    Institute of Scientific and Technical Information of China (English)

    吴旭; 何霄峰; 甘蔚钰

    2009-01-01

    在Pro/E软件环境下,利用二次开发工具Pro/Tookit结合Pro/E的布局功能开发了一套针对卷烟包装设备的专用零件参数化CAD系统.该系统具有便捷的用户菜单,通过修改布局文件中烟包、烟条规格参数,可以对卷烟包装设备专用零件进行自动参数化设计,并输出相应的三维零件图、三维装配图和二维工程图.同时,系统实现了零件的自动设计和装配检验,大大缩短了产品的开发时间,提高了设计效率.%Based on Pro/Engineering software, a parametric designing CAD system for parts specially used in cigarette packaging equipment had been developed by Pro/Toolkit and the Layout function. A user-friendly menu was provided in the system. The parametric part de-signing for the parts could be conducted by changing the parameters in the layout. And the 3D part models, 3D assembly models and 2D engineering drawings could also be output. Au-tomatic part designing and assembly testing had been realized in the system, which could greatly shorten the product's development time and improve the design quality.

  8. 基于骨架模型曲柄滑块机构的参数化设计与仿真%Parametric Design and Simulation of Slider-Crank Mechanism Based on Skeleton Model

    Institute of Scientific and Technical Information of China (English)

    康爱军; 陈飞; 程刚

    2012-01-01

    对曲柄滑块机构进行了几何分析并确定了其设计参数的取值范围.基于Pro/E的Top-Down设计方法,建立了曲柄滑块机构的骨架模型.通过Pro/Program编程和添加关系式实现了骨架模型参数化设计.基于骨架模型建立了曲柄滑块机构装配模型,并在Pro/Mechanism模块中进行运动学仿真分析,成功地建立了一个参数化设计与仿真系统.该系统能够获取曲柄滑块机构任意位置的运动规律,具有可视化、参数化、操作简单等特点,为教学与生产实践提供指导.%Geometric analysis is done and value ranges of design parameters are confirmed for Slider-crank Mechanism.Based on the Top-Down design in Pro/E,the skeleton model for slider-crank Mechanism is builtAnd parametric design for the skeleton model is realized by programming and adding relations in Pro/Program-Based on the skeleton model,an assembly model is built,and is kinematically simulated in Pno/Mechanisin.So α parametric design and simulation system for slider-crank mechanism is finally estab-lishedWith this system,movement law in any position of slider-crank mechanism can be obtained. This system is characterized with its visualization and parameterization and easy ope ration,which may provide guidance for teaching and productive practice.

  9. Analysis of lomustine drug content in FDA-approved and compounded lomustine capsules.

    Science.gov (United States)

    KuKanich, Butch; Warner, Matt; Hahn, Kevin

    2017-02-01

    OBJECTIVE To determine the lomustine content (potency) in compounded and FDA-approved lomustine capsules. DESIGN Evaluation study. SAMPLE 2 formulations of lomustine capsules (low dose [7 to 11 mg] and high dose [40 to 48 mg]; 5 capsules/dose/source) from 3 compounders and from 1 manufacturer of FDA-approved capsules. PROCEDURES Lomustine content was measured by use of a validated high-pressure liquid chromatography method. An a priori acceptable range of 90% to 110% of the stated lomustine content was selected on the basis of US Pharmacopeia guidelines. RESULTS The measured amount of lomustine in all compounded capsules was less than the stated content (range, 59% to 95%) and was frequently outside the acceptable range (failure rate, 2/5 to 5/5). Coefficients of variation for lomustine content ranged from 4.1% to 16.7% for compounded low-dose capsules and from 1.1% to 10.8% for compounded high-dose capsules. The measured amount of lomustine in all FDA-approved capsules was slightly above the stated content (range, 104% to 110%) and consistently within the acceptable range. Coefficients of variation for lomustine content were 0.5% for low-dose and 2.3% for high-dose FDA-approved capsules. CONCLUSIONS AND CLINICAL RELEVANCE Compounded lomustine frequently did not contain the stated content of active drug and had a wider range of lomustine content variability than did the FDA-approved product. The sample size was small, and larger studies are needed to confirm these findings; however, we recommend that compounded veterinary formulations of lomustine not be used when appropriate doses can be achieved with FDA-approved capsules or combinations of FDA-approved capsules.

  10. Capsule implosions driven by dynamic hohlraum x-rays

    Science.gov (United States)

    Bailey, James

    2005-10-01

    Dynamic hohlraum experiments at the Z facility already implode capsules with up to 80 kJ absorbed x-ray energy. However, many challenging issues remain for ICF. The present experiments use diagnostic capsules to address two of these issues: symmetry measurement and control and building understanding of the capsule/hohlraum implosion system. A suite of x-ray spectrometers record time and space resolved spectra emitted by Ar tracer atoms in the implosion core, simultaneously from up to three different quasi-orthogonal directions. Comparing the results with simulation predictions provide severe tests of understanding. These data also can used to produce a tomographic reconstruction of the time resolved core temperature and density profiles. X-ray and neutron diagnostics are used to examine how the implosion conditions change as the capsule design changes. The capsule design changes include variations in CH wall thickness and diameter, Ge-doped CH shells, and SiO2 shells. In addition, a new campaign investigating Be capsule implosions is beginning. Be capsules may offer superior performance for dynamic hohlraum research and it may be possible to investigate NIF-relevant Be implosion issues such as the fill tube effects, sensitivity to columnar growth associated with sputtered Be capsule fabrication, and the effect of Cu dopants on implosion conditions. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the U.S. Dept. of Energy under contract No. DE-AC04-94AL85000. * In collaboration with G.A. Rochau, G.A. Chandler, S.A. Slutz, P.W. Lake, G. Cooper, G.S. Dunham, R.J. Leeper, R. Lemke, T.A. Mehlhorn, T.J. Nash, D.S. Nielsen, K. Peterson, C.L. Ruiz, D.B. Sinars, J. Torres, W. Varnum, Sandia; R.C. Mancini, T.J. Buris-Mog, UNR; I. Golovkin, J.J. MacFarlane, PRISM; A. Nikro, D. Steinman, J.D. Kilkenny, H. Xu, General Atomics; M. Bump, T.C. Moore, K-tech; D.G. Schroen, Schafer

  11. Status of DOE/JAERI collaborative program phase II and phase III capsules

    Energy Technology Data Exchange (ETDEWEB)

    Robertson, J.P.; Lenox, K.E. [Oak Ridge National Lab., TN (United States); Ioka, I.; Wakai, E.

    1997-04-01

    Significant progress has been made during the last year in the post-irradiation examinations (PIE) of the specimens from nine DOE ORNL/JAERI collaborative capsules and in the design and fabrication of four additional capsules. JP21, JP22, CTR-62, and CTR-63 were disassembled, JP20 tensile specimens were tested, and a variety of specimens from the RB-60J-1, 330J-1, and 400J-1 capsules were tested. Fabrication of RB-11J and 12J was completed and progress made in the matrix finalization and design of RB-10J and JP25.

  12. Orbital Thermal Control of the Mercury Capsule

    Science.gov (United States)

    Weston, Kenneth C.

    1960-01-01

    The approach to orbital thermal control of the Project Mercury capsule environment is relatively unsophisticated compared with that for many unmanned satellites. This is made possible by the relatively short orbital flight of about 4 1/2 hours and by the presence of the astronaut who is able to monitor the capsule systems and compensate for undesirable thermal conditions. The general external features of the Mercury configuration as it appears in the orbital phase of flight are shown. The conical afterbody is a double-wall structure. The inner wall serves as a pressure vessel for the manned compartment, and the outer wall, of shingle type construction, acts as a radiating shield during reentry. Surface treatment of the shingles calls for a stably oxidized surface to minimize reentry temperatures. The shingles are supported by insulated stringers attached to the inner skin. Areas between stringers are insulated by blankets of Thermoflex insulation. This insulation is especially effective at high altitude due to the reduction of its thermal conductivity with decreasing pressure. As a result of the design of the afterbody for the severe reentry conditions, the heat balance on the manned compartment indicates the necessity for moderate internal cooling to compensate for the heat generation due to human and electrical sources. This cooling is achieved by the controlled vaporization of water in the cabin and astronaut-suit heat exchangers.

  13. Isotretinoin Oil-Based Capsule Formulation Optimization

    Directory of Open Access Journals (Sweden)

    Pi-Ju Tsai

    2013-01-01

    Full Text Available The purpose of this study was to develop and optimize an isotretinoin oil-based capsule with specific dissolution pattern. A three-factor-constrained mixture design was used to prepare the systemic model formulations. The independent factors were the components of oil-based capsule including beeswax (X1, hydrogenated coconut oil (X2, and soybean oil (X3. The drug release percentages at 10, 30, 60, and 90 min were selected as responses. The effect of formulation factors including that on responses was inspected by using response surface methodology (RSM. Multiple-response optimization was performed to search for the appropriate formulation with specific release pattern. It was found that the interaction effect of these formulation factors (X1X2, X1X3, and X2X3 showed more potential influence than that of the main factors (X1, X2, and X3. An optimal predicted formulation with Y10 min, Y30 min, Y60 min, and Y90 min release values of 12.3%, 36.7%, 73.6%, and 92.7% at X1, X2, and X3 of 5.75, 15.37, and 78.88, respectively, was developed. The new formulation was prepared and performed by the dissolution test. The similarity factor f2 was 54.8, indicating that the dissolution pattern of the new optimized formulation showed equivalence to the predicted profile.

  14. Thermal analysis of an irradiation capsule for high-temperature materials to be used in future nuclear systems

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Man Soon; Choo, Kee Nam; Kim, Sung Ryul [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of). Dept. of Neutron Application Technology

    2016-05-15

    The requirement of irradiation of materials at high temperature are gradually increasing with the development of Gen-IV (Generation-IV) reactors, which will be operated at high temperatures and under a high neutron flux. To overcome the restrictions for the high temperature use of Al thermal media of the existing standard capsule, a new capsule was designed and fabricated. Through the irradiation test, the structural integrity and safety of the capsule during irradiation at high temperature were confirmed.

  15. A study on the development of instrumented capsule for the material irradiation test

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Young Hwan; Park, J. M.; Choo, K. N.; Maeng, W. Y.; Park, D. K.; Oh, J. M.; Park, S. J.; Jung, S. H.; Park, J. S.; Kim, T. R.; Park, J. H.; Yang, S. Y.; Jun, Y. K.; Yang, S. H.

    1997-08-01

    Extensive efforts have been made to establish design and manufacturing technology for the instrumented capsule and its related system, which should be compatible with the HANARO`s characteristics. (author). 86 refs., 45 tabs., 146 figs.

  16. Research and parametric design of automotive engine crankshaft flywheel based on the Pro/E%基于Pro/E的汽车发动机曲轴飞轮组的三维参数化设计与研究

    Institute of Scientific and Technical Information of China (English)

    胡昊

    2012-01-01

    The design concept of the crankshaft seriation was put forward based on the Pio/E.Firstly through segmenting the structure feature of crankshaft, products the relative feature database was estab -lished-Then the shortcomings of current three-dimensional parametric design of mechanical products was analyzed using VC++6.0 as a development tool,With Pro/E software advanced development toolkit that comes with Pro/TOOLKIT three-dimensional parametric design system of automotive engine crankshaft flywheel was developed based on Pro/E to achieve design parameterization of the car crankshaft flywheels. Through project development duplication of most of the design drawings was avoided,which improves the design efficiency and accuracy,speeds up three-dimensional design process,and shortens the design cycle as well with important application value.%提出了基于Pro/E软件的曲轴系列化的设计理念.通过对曲轴产品结构的特征划分,建立了相应的特征数据库.分析了目前机械产品三维参数化设计的不足,利用VC++6.0作为系统开发工具,借助Pro/E软件自带的高级开发工具包Pro/TOOLKIT,开发了基于Pro/E的汽车发动机曲轴飞轮组的三维参数化设计系统,实现了汽车曲轴飞轮组的参数化设计.通过项目的开发避免了大部分工程图的重复设计工作,提高了设计效率和设计精度.实现了三维设计进程的加速,缩短了产品的设计周期,具有重要的实际应用价值.

  17. Genetic organisation of the capsule transport gene region from Haemophilus paragallinarum

    Directory of Open Access Journals (Sweden)

    O. De Smidt

    2004-11-01

    Full Text Available The region involved in export of the capsule polysaccharides to the cell surface of Haemophilus paragallinarum was cloned and the genetic organisation determined. Degenerate primers designed from sequence alignment of the capsule transport genes of Haemophilus influenzae, Pasteurella multocida and Actinobacillus pleuropneumoniae were used to amplify a 2.6 kb fragment containing a segment of the H. paragallinarum capsule transport gene locus. This fragment was used as a digoxigenin labelled probe to isolate the complete H. paragallinarum capsule transport gene locus from genomic DNA. The sequence of the cloned DNA was determined and analysis revealed the presence of four genes, each showing high homology with known capsule transport genes. The four genes were designated hctA, B, C and D (for H. paragallinarum capsule transport genes and the predicted products of these genes likely encode an ATP-dependent export system responsible for transport of the capsule polysaccharides to the cell surface, possibly a member of a super family designated ABC (ATP-binding cassette transporters.

  18. Parametric Aided Design System of Axle Based on AutoCAD VBA%基于AutoCAD VBA的参数化辅助轴设计系统

    Institute of Scientific and Technical Information of China (English)

    王鹏

    2014-01-01

    Based on the AutoCAD ActiveX and VBA technology, a kind of parametric aided design system of axle is developed through carrying out the secondary development on AutoCAD. It could complete the axle’s design checking to the theory of axle’s strength. And it would generate the drawing of the axle automatically according to the users’ inputted parameters. In order to realize the automation of the process of axle’ s aided design, structural design, data processing and inquiring, mechanical calculation, strength checking and parametric drawing modules are integrated to axle aided design system, which based on the theory of solid modeling of feature and the technology of dimension-driving. The system can reduce the workload of designers effectively, improve design quality and efficiency, and have certain applicable value.%基于AutoCAD ActiveX和VBA技术,通过对AutoCAD进行二次开发,构建了一种轴的参数化辅助设计系统。系统能按照用户输入的相关参数,根据轴的强度校核理论完成轴的设计工作,最终自动生成零件图。为了实现轴的辅助设计流程的自动化,系统集成了结构设计、数据处理与查询、力学计算、强度校核和参数化绘图等模块,同时,利用基于特征实体造型理论和参数化尺寸驱动技术进行系统的开发。该系统可有效减少设计人员的工作量、提高设计质量和设计效率,具有一定的应用价值。

  19. 基于辅助线滞生法的Auto CAD R12参数化设计系统%Auto CAD R12 Parametric Design System Based on the Detained Auxiliary Line

    Institute of Scientific and Technical Information of China (English)

    郭启全; 周克绳

    1996-01-01

    本文提出了一种在Auto CAD R12环境下,用C语言(基于ADS)开发二维图形参数化设计的新方法辅助线滞生法.解决了辅助线滞生法与ADS具体结合中的技术难题;阐述了实元素悬挂到辅助元素上的新思想,实现了尺寸驱动;为用户众多的Auto CAD R12增加了新功能.基于该方法的Auto CAD R12参数化设计系统(Auto CAD R12 Parametric Design System--APDS)已用于悬挂输送机、管道油阀及半挂自卸车的设计绘图.

  20. Parametric Models of Periodogram

    Indian Academy of Sciences (India)

    P. Mohan; A. Mangalam; S. Chattopadhyay

    2014-09-01

    The maximum likelihood estimator is used to determine fit parameters for various parametric models of the Fourier periodogram followed by the selection of the best-fit model amongst competing models using the Akaike information criteria. This analysis, when applied to light curves of active galactic nuclei can be used to infer the presence of quasi-periodicity and break or knee frequencies. The extracted information can be used to place constraints on the mass, spin and other properties of the putative central black hole and the region surrounding it through theoretical models involving disk and jet physics.

  1. Investigation on the Optimum Performance and Parametric Design of a Variety of Energy Conversion Systems%多种能量转换系统的性能优化与参数设计的研究

    Institute of Scientific and Technical Information of China (English)

    林国星; 陈金灿

    2011-01-01

    Saving energy, increasing efficiency of energy utilization and empoldering new and renewable clean energy sources are emphases of developing energy source in the coming years. The performance optimization and parametric design of energy conversion systems is one of the key science problems in energy utilization with high efficiency. In the present paper, some important research results involving the optimum performance and parametric design of a variety of energy conversion systems, such as the magnetic refrigeration, semiconductor thermoelectric devices, thermal utilization of solar energy , chemical engines and chemical pumps , fuel cell hybrid systems , water electrolysis systems for hydrogen production, Brownian motors , quantum thermodynamic cycle systems , and so on,are introduced in combination with both the research status at home and abroad and the research work of our group in recent years.%节能、提高能效、开发新能源(包括可再生清洁能源)是今后能源发展的重点,而能量转换系统的性能优化与参数设计是高效利用能源的一个关键科学问题.结合国内外的研究现状和本研究组近年来的研究工作,介绍在磁制冷、半导体热电器件、太阳能热利用、化学机与化学泵、燃料电池及其耦合系统、电解水制氢系统、布朗马达及量子热力学循环等能量转换系统的性能优化与参数设计方面所取得的一些重要成果.

  2. Thermal Analysis of a Dry Storage Concept for Capsule Dry Storage Project

    Energy Technology Data Exchange (ETDEWEB)

    JOSEPHSON, W S

    2003-09-04

    There are 1,936 cesium (Cs) and strontium (Sr) capsules stored in pools at the Waste Encapsulation and Storage Facility (WESF). These capsules will be moved to dry storage on the Hanford Site as an interim measure to reduce risk. The Cs/Sr Capsule Dry Storage Project is conducted under the assumption that the capsules will eventually be moved to the repository at Yucca Mountain, and the design criteria include requirements that will facilitate acceptance at the repository. The storage system must also permit retrieval of capsules in the event that vitrification of the capsule contents is pursued. The Capsule Advisory Panel (CAP) was created by the Project Manager for the Hanford Site Capsule Dry Storage Project (CDSP). The purpose of the CAP is to provide specific technical input to the CDSP; to identify design requirements; to ensure design requirements for the project are conservative and defensible; to identify and resolve emerging, critical technical issues, as requested; and to support technical reviews performed by regulatory organizations, as requested. The CAP will develop supporting and summary documents that can be used as part of the technical and safety bases for the CDSP. The purpose of capsule dry storage thermal analysis is to: (1) Summarize the pertinent thermal design requirements sent to vendors, (2) Summarize and address the assumptions that underlie those design requirements, (3) Demonstrate that an acceptable design exists that satisfies the requirements, (4) Identify key design features and phenomena that promote or impede design success, (5) Support other CAP analyses such as corrosion and integrity evaluations, and (6) Support the assessment of proposed designs. It is not the purpose of this report to optimize or fully analyze variations of postulated acceptable designs. The present evaluation will indicate the impact of various possible design features, but not systematically pursue design improvements obtainable through analysis

  3. A finite element parametric modeling technique of aircraft wing structures

    Institute of Scientific and Technical Information of China (English)

    Tang Jiapeng; Xi Ping; Zhang Baoyuan; Hu Bifu

    2013-01-01

    A finite element parametric modeling method of aircraft wing structures is proposed in this paper because of time-consuming characteristics of finite element analysis pre-processing. The main research is positioned during the preliminary design phase of aircraft structures. A knowledge-driven system of fast finite element modeling is built. Based on this method, employing a template parametric technique, knowledge including design methods, rules, and expert experience in the process of modeling is encapsulated and a finite element model is established automatically, which greatly improves the speed, accuracy, and standardization degree of modeling. Skeleton model, geometric mesh model, and finite element model including finite element mesh and property data are established on parametric description and automatic update. The outcomes of research show that the method settles a series of problems of parameter association and model update in the pro-cess of finite element modeling which establishes a key technical basis for finite element parametric analysis and optimization design.

  4. Development of OpenGL-based Parametric Design System for Special Shape Pack- aging Carton%基于OpenGL的异型包装纸盒参数化设计系统的研究

    Institute of Scientific and Technical Information of China (English)

    陈锦昌; 曾健

    2012-01-01

    给出了异型包装纸盒参数化设计中关键参数的确定方法,以系统中的一个异型盒型为例,论述了异型盒参数化设计过程中各参数之间的关系,确定了参数化设计的关键参数,并给出了相关的计算公式。开发了一套能展示立体的线框图、贴图后的效果图以及平面展开的线框图等的设计系统,为异型包装纸盒的设计提供便利。%The determination method of key parameters for parametric design of special shape packaging carton was introduced. Relationship among the parameters in the course of design was discussed with example. The key parameters of the example were determined and the correlative calculation formulas were provided. A corresponding design system with the functions of showing line frame model, rendering model, and evolving drawing etc. was developed, which provide convenience for design of special shape packaging carton.

  5. Design of Beam-forming of Broadband Steerable-Parametric Array%相控参量阵波束合成设计

    Institute of Scientific and Technical Information of China (English)

    张富东; 徐利梅; 陈敏

    2013-01-01

    The simulation and analysis of beam-forming about broadband parametric array with rectangle trans-duction array and loop transduction array have been completed in this paper. The results show that under the condition of the same array element numbers with N=9 and same array size with rm = 49 mm,the - 3 dB beam width of rectangle array is about 6. 3° (comparing to 7. 4° of loop array), and its side-lobe amplitude is inhibited completely (comparing to the value of 10% about loop array). It means that the rectangle array is more effective at beam directivity improving and side-lobe amplitude inhibition. The method of element signal time-delay is used to parametric array signals beam-steering implement. As a result of Beam-steering, the beam main-lobe turned to width more, its peak value of amplitude reduces obviously,and it doesn't point to the direction which is planned to. The reasons of these problems are discussed in this paper. It is verified that these problems could be corrected by increasing array elements and spreading array size.%针对矩形和圆环形换能器阵列,完成了宽带参量阵信号的波束合成仿真与结果比较分析.仿真结果表明,同等阵元个数N=9、相似阵列边界半径rm=49 mm条件下,矩形阵列差频波波束主瓣-3 dB指向角约为6.3°(圆环阵列约为7.4°),旁瓣几乎被完全抑制(圆环阵列约为主瓣峰值的10%),矩形阵列更利于提高主瓣指向性和抑制旁瓣幅度.针对矩形阵列,该文仿真分析了采用阵元信号延时方法实现参量阵信号波束偏转时的各波束特征,仿真结果显示,偏转后波束存在主瓣峰值点幅值削弱、主瓣峰值点未对准预定方向、主瓣宽度增大等问题.分析表明,以上问题可通过增加阵元数目及增大阵列尺寸进行修正.

  6. A disposable and multifunctional capsule for easy operation of microfluidic elastomer systems

    Science.gov (United States)

    Thorslund, Sara; Nguyen, Hugo; Läräng, Thomas; Barkefors, Irmeli; Kreuger, Johan

    2011-12-01

    The global lab-on-chip and microfluidic markets for cell-based assays have been predicted to grow considerably, as novel microfluidic systems enable cell biologists to perform in vitro experiments at an unprecedented level of experimental control. Nevertheless, microfluidic assays must, in order to compete with conventional assays, be made available at easily affordable costs, and in addition be made simple to operate for users having no previous experience with microfluidics. We have to this end developed a multifunctional microfluidic capsule that can be mass-produced at low cost in thermoplastic material. The capsule enables straightforward operation of elastomer inserts of optional design, here exemplified with insert designs for molecular gradient formation in microfluidic cell culture systems. The integrated macro-micro interface of the capsule ensures reliable connection of the elastomer fluidic structures to an external perfusion system. A separate compartment in the capsule filled with superabsorbent material is used for internal waste absorption. The capsule assembly process is made easy by integrated snap-fits, and samples within the closed capsule can be analyzed using both inverted and upright microscopes. Taken together, the capsule concept presented here could help accelerate the use of microfluidic-based biological assays in the life science sector.

  7. The fast parametric slantlet transform with applications

    Science.gov (United States)

    Agaian, Sos S.; Tourshan, Khaled; Noonan, Joseph P.

    2004-05-01

    Transform methods have played an important role in signal and image processing applications. Recently, Selesnick has constructed the new orthogonal discrete wavelet transform, called the slantlet wavelet, with two zero moments and with improved time localization. The discrete slantlet wavelet transform is carried out by an existing filterbank which lacks a tree structure and has a complexity problem. The slantlet wavelet has been successfully applied in compression and denoising. In this paper, we present a new class of orthogonal parametric fast Haar slantlet transform system where the slantlet wavelet and Haar transforms are special cases of it. We propose designing the slantlet wavelet transform using Haar slantlet transform matrix. A new class of parametric filterbanks is developed. The behavior of the parametric Haar slantlet transforms in signal and image denoising is presented. We show that the new technique performs better than the slantlet wavelet transform in denoising for piecewise constant signals. We also show that the parametric Haar slantlet transform performs better than the cosine and Fourier transforms for grey level images.

  8. Capsule Development and Utilization for Material Irradiation Tests

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bong Goo; Kang, Y. H.; Cho, M. S. (and others)

    2007-06-15

    The essential technology for an irradiation test of materials and nuclear fuel has been successively developed and utilized to meet the user's requirements in Phase I(July 21, 1997 to March 31, 2000). It enables irradiation tests to be performed for a non-fissile material under a temperature control(300{+-}10 .deg. C) in a He gas environment, and most of the irradiation tests for the internal and external users are able to be conducted effectively. The basic technology was established to irradiate a nuclear fuel, and a creep capsule was also developed to measure the creep property of a material during an irradiation test in HANARO in Phase II(April 1, 2000 to March 31, 2003). The development of a specific purpose capsule, essential technology for a re-irradiation of a nuclear fuel, advanced technology for an irradiation of materials and a nuclear fuel were performed in Phase III(April 1, 2003 to February 28, 2007). Therefore, the technology for an irradiation test was established to support the irradiation of materials and a nuclear fuel which is required for the National Nuclear R and D Programs. In addition, an improvement of the existing capsule design and fabrication technology, and the development of an instrumented capsule for a nuclear fuel and a specific purpose will be able to satisfy the user's requirements. In order to support the irradiation test of materials and a nuclear fuel for developing the next generation nuclear system, it is also necessary to continuously improve the design and fabrication technology of the existing capsule and the irradiation technology.

  9. Colon Capsule Endoscopy: Review and Perspectives

    Directory of Open Access Journals (Sweden)

    David Friedel

    2016-01-01

    Full Text Available Colon capsule endoscopy utilizing PillCam COLON 2 capsule allows for visualization potentially of the entire colon and is currently approved for patients who cannot withstand the rigors of traditional optical colonoscopy (OC and associated sedation as well as those that had an OC that was incomplete for technical reasons other than a poor preparation. We will then describe the prior experience and current status of colon capsule endoscopy.

  10. Ionization Cooling using Parametric Resonances

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Rolland P.

    2008-06-07

    Ionization Cooling using Parametric Resonances was an SBIR project begun in July 2004 and ended in January 2008 with Muons, Inc., (Dr. Rolland Johnson, PI), and Thomas Jefferson National Accelerator Facility (JLab) (Dr. Yaroslav Derbenev, Subcontract PI). The project was to develop the theory and simulations of Parametric-resonance Ionization Cooling (PIC) so that it could be used to provide the extra transverse cooling needed for muon colliders in order to relax the requirements on the proton driver, reduce the site boundary radiation, and provide a better environment for experiments. During the course of the project, the theoretical understanding of PIC was developed and a final exposition is ready for publication. Workshops were sponsored by Muons, Inc. in May and September of 2007 that were devoted to the PIC technique. One outcome of the workshops was the interesting and somewhat unexpected realization that the beam emittances using the PIC technique can get small enough that space charge forces can be important. A parallel effort to develop our G4beamline simulation program to include space charge effects was initiated to address this problem. A method of compensating for chromatic aberrations by employing synchrotron motion was developed and simulated. A method of compensating for spherical aberrations using beamline symmetry was also developed and simulated. Different optics designs have been developed using the OptiM program in preparation for applying our G4beamline simulation program, which contains all the power of the Geant4 toolkit. However, no PIC channel design that has been developed has had the desired cooling performance when subjected to the complete G4beamline simulation program. This is believed to be the consequence of the difficulties of correcting the aberrations associated with the naturally large beam angles and beam sizes of the PIC method that are exacerbated by the fringe fields of the rather complicated channel designs that have been

  11. Capsule Ablator Inflight Performance Measurements Via Streaked Radiography Of ICF Implosions On The NIF*

    Science.gov (United States)

    Dewald, E. L.; Tommasini, R.; Mackinnon, A.; MacPhee, A.; Meezan, N.; Olson, R.; Hicks, D.; LePape, S.; Izumi, N.; Fournier, K.; Barrios, M. A.; Ross, S.; Pak, A.; Döppner, T.; Kalantar, D.; Opachich, K.; Rygg, R.; Bradley, D.; Bell, P.; Hamza, A.; Dzenitis, B.; Landen, O. L.; MacGowan, B.; LaFortune, K.; Widmayer, C.; Van Wonterghem, B.; Kilkenny, J.; Edwards, M. J.; Atherton, J.; Moses, E. I.

    2016-03-01

    Streaked 1-dimensional (slit imaging) radiography of 1.1 mm radius capsules in ignition hohlraums was recently introduced on the National Ignition Facility (NIF) and gives an inflight continuous record of capsule ablator implosion velocities, shell thickness and remaining mass in the last 3-5 ns before peak implosion time. The high quality data delivers good accuracy in implosion metrics that meets our requirements for ignition and agrees with recently introduced 2-dimensional pinhole radiography. Calculations match measured trajectory across various capsule designs and laser drives when the peak laser power is reduced by 20%. Furthermore, calculations matching measured trajectories give also good agreement in ablator shell thickness and remaining mass.

  12. Fusion of Gothic Architectural Style and Modern Reticulated Shell Structure Design:Parametric Design and Shape Optimization of Pyramid Type Folded Plate Latticed Shell%哥特式建筑风格与现代网壳结构设计的融合--角锥折板网壳参数化设计及形状优化

    Institute of Scientific and Technical Information of China (English)

    赵忠佳; 鹿少博; 鹿晓阳; 赵晓伟; 李龙

    2016-01-01

    借鉴哥特式建筑风格和角锥折板网壳特点,采用APDL( ANSYS parametric design language )参数化设计语言,研制了五种不同网格类型的角锥折板网壳参数化设计宏程序,实现了给定跨度S、矢高F、环向对称区域份数Kn和径向节点圈数Nx等参数下,五种类型角锥折板网壳参数化设计。对五种网壳进行了受力性能分析,探究了网壳结构最不利位移、最不利应力随矢高变化规律:并以结构耗钢量为目标函数,以Kn、Nx为设计变量进行了形状优化。建模实例表明该参数化设计宏程序方便、快捷,形状优化设计给出了在跨度、矢高不变时结构耗钢量随网格数变化规律及耗钢量最小的最优网格数。%Learn from the Gothic style and the characteristics of pyramid folded plate latticed shell ,by using de-sign language APDL ( ANSYS Parametric Design Language ) ,developed the macro programs of parametric design of five types of pyramid type of folded plate latticed shell , parametric design of five types of pyramid type of folded plate latticed shell is realized with the given parameter of span S, the vector high F, ring to symmeric regional cop-ies number Kn and radial node ring number Nx.And had carried on analasis of force performance , explored the change rule of the most unfavorable displacement and the most unfavorable stress with the change of vector height of reticulated shell structure .The shape optimization is carried out by using the steel consumption of structure as the objective function , Kn and Nx as the design variable .Modeling examples demonstrate that the macro program of de-sign is convenient and quick , shape optimization design can get the change rule of steel consumption with the grid number changed when the span and the height of the vector are unchanged and also can get optimal mesh number of minimum steel consumption .

  13. Parametric Design and Research of A 2-DOF Parallel Manipulator%两自由度并联机械手的参数化设计与研究

    Institute of Scientific and Technical Information of China (English)

    洪帅华; 白国振; 全松; 刘淼

    2015-01-01

    以两自由度并联机械手为研究对象,运用ADAMS软件建立虚拟样机模型并仿真,并采用并联机械手设备对模型进行验证。以主动臂最大转角范围为优化目标,对并联机械手的虚拟样机的主动臂臂长、从动臂臂长、位置偏置距离进行参数化设计和优化设计。%In this paper ,a two degree of freedom parallel manipulator was taken as the research object ,the virtual prototype model of the manipulator was set up using ADAMS software ,and the simulation study was conducted .Meanwhile ,the correctness of the model was verified by use of a parallel manipulator device .With the initiative arm maximum range of angle as the optimization objective ,the manipulator’s active arm ,driven arm ,offset position as the design variables ,the optimization design and parametric design of the virtual prototype was carried out .

  14. Application of Knowledge and UG Secondary Development Technology in Parametric Design System of Spreader%基于知识与 UG 二次开发的吊具参数化设计系统

    Institute of Scientific and Technical Information of China (English)

    王小明; 王耕耘; 张文明; 王华侨

    2016-01-01

    由于作业时需要具有很高的安全性,因此吊具结构尺寸的设计和安全性检验便成为关键。在原有设计方法的基础上,利用UG7.5开发了吊具设计系统,并采用 ANSYS对吊具进行有限元分析。根据计算和有限元分析结果,优化了吊具的结构尺寸,实现了吊具在生产前的检验与优化。%Because of the high security requirements of spreader ,the structure design and safety testing of spreader have become important .Based on the original design methods ,a parametric design system of spreader was developed by using UG7 .5 ,and this paper conducted finite element analysis for the spreader with ANSYS .According to the results of the calculation and finite element analysis ,the structural dimensions of the spreader could be improved ,and the spreader could be inspected and optimized before production .

  15. Mechanical Parametric Oscillations and Waves

    Science.gov (United States)

    Dittrich, William; Minkin, Leonid; Shapovalov, Alexander S.

    2013-01-01

    Usually parametric oscillations are not the topic of general physics courses. Probably it is because the mathematical theory of this phenomenon is relatively complicated, and until quite recently laboratory experiments for students were difficult to implement. However parametric oscillations are good illustrations of the laws of physics and can be…

  16. Nanoscale electromechanical parametric amplifier

    Energy Technology Data Exchange (ETDEWEB)

    Aleman, Benjamin Jose; Zettl, Alexander

    2016-09-20

    This disclosure provides systems, methods, and apparatus related to a parametric amplifier. In one aspect, a device includes an electron source electrode, a counter electrode, and a pumping electrode. The electron source electrode may include a conductive base and a flexible conductor. The flexible conductor may have a first end and a second end, with the second end of the flexible conductor being coupled to the conductive base. A cross-sectional dimension of the flexible conductor may be less than about 100 nanometers. The counter electrode may be disposed proximate the first end of the flexible conductor and spaced a first distance from the first end of the flexible conductor. The pumping electrode may be disposed proximate a length of the flexible conductor and spaced a second distance from the flexible conductor.

  17. Parametric modal transition systems

    DEFF Research Database (Denmark)

    Beneš, Nikola; Křetínský, Jan; Larsen, Kim Guldstrand;

    2011-01-01

    Modal transition systems (MTS) is a well-studied specification formalism of reactive systems supporting a step-wise refinement methodology. Despite its many advantages, the formalism as well as its currently known extensions are incapable of expressing some practically needed aspects in the refin......Modal transition systems (MTS) is a well-studied specification formalism of reactive systems supporting a step-wise refinement methodology. Despite its many advantages, the formalism as well as its currently known extensions are incapable of expressing some practically needed aspects...... in the refinement process like exclusive, conditional and persistent choices. We introduce a new model called parametric modal transition systems (PMTS) together with a general modal refinement notion that overcome many of the limitations and we investigate the computational complexity of modal refinement checking....

  18. Avoiding the parametric roll

    Science.gov (United States)

    Acomi, Nicoleta; Ancuţa, Cristian; Andrei, Cristian; Boştinǎ, Alina; Boştinǎ, Aurel

    2016-12-01

    Ships are mainly built to sail and transport cargo at sea. Environmental conditions and state of the sea are communicated to vessels through periodic weather forecasts. Despite officers being aware of the sea state, their sea time experience is a decisive factor when the vessel encounters severe environmental conditions. Another important factor is the loading condition of the vessel, which triggers different behaviour in similar marine environmental conditions. This paper aims to analyse the behaviour of a port container vessel in severe environmental conditions and to estimate the potential conditions of parametric roll resonance. Octopus software simulation is employed to simulate vessel motions under certain conditions of the sea, with possibility to analyse the behaviour of ships and the impact of high waves on ships due to specific wave encounter situations. The study should be regarded as a supporting tool during the decision making process.

  19. The development and advantages of beryllium capsules for the National Ignition Facility

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, D.C.; Bradley, P.A.; Hoffman, N.M. [Los Alamos National Lab., NM (United States)] [and others

    1998-02-01

    Capsules with beryllium ablators have long been considered as alternatives to plastic for the National Ignition Facility laser ; now the superior performance of beryllium is becoming well substantiated. Beryllium capsules have the advantages of relative insensitivity to instability growth, low opacity, high tensile strength, and high thermal conductivity. 3-D calculation with the HYDRA code NTIS Document No. DE-96004569 (M. M. Marinak et.al. in UCRL-LR-105821-95-3) confirm 2-D LASNEX U. B. Zimmerman and W. L. Kruer, Comments Plasmas Phys. Controlled Thermonucl. Fusion, 2, 51(2975) results that particular beryllium capsule designs are several times less sensitive than the CH point design to instability growth from DT ice roughness. These capsule designs contain more ablator mass and leave some beryllium unablated at ignition. By adjusting the level of copper dopant, the unablated mass can increase or decrease, with a corresponding decrease or increase in sensitivity to perturbations. A plastic capsule with the same ablator mass as the beryllium and leaving the same unablated mass also shows this reduced perturbation sensitivity. Beryllium`s low opacity permits the creation of 250 eV capsule designs. Its high tensile strength allows it to contain DT fuel at room temperature. Its high thermal conductivity simplifies cryogenic fielding.

  20. Planar Parametrization in Isogeometric Analysis

    DEFF Research Database (Denmark)

    Gravesen, Jens; Evgrafov, Anton; Nguyen, Dang-Manh

    2012-01-01

    Before isogeometric analysis can be applied to solving a partial differential equation posed over some physical domain, one needs to construct a valid parametrization of the geometry. The accuracy of the analysis is affected by the quality of the parametrization. The challenge of computing...... optimization. It utilizes an expensive non-linear method for constructing/updating a high quality reference parametrization, and an inexpensive linear method for maintaining the parametrization in the vicinity of the reference one. We describe several linear and non-linear parametrization methods, which...... are suitable for our framework. The non-linear methods we consider are based on solving a constrained optimization problem numerically, and are divided into two classes, geometry-oriented methods and analysis-oriented methods. Their performance is illustrated through a few numerical examples....

  1. Kingella kingae Expresses Four Structurally Distinct Polysaccharide Capsules That Differ in Their Correlation with Invasive Disease

    Science.gov (United States)

    Porsch, Eric A.; Seed, Patrick C.; Heiss, Christian; Naran, Radnaa; Amit, Uri; Yagupsky, Pablo; Azadi, Parastoo; St. Geme, Joseph W.

    2016-01-01

    Kingella kingae is an encapsulated gram-negative organism that is a common cause of osteoarticular infections in young children. In earlier work, we identified a glycosyltransferase gene called csaA that is necessary for synthesis of the [3)-β-GalpNAc-(1→5)-β-Kdop-(2→] polysaccharide capsule (type a) in K. kingae strain 269–492. In the current study, we analyzed a large collection of invasive and carrier isolates from Israel and found that csaA was present in only 47% of the isolates. Further examination of this collection using primers based on the sequence that flanks csaA revealed three additional gene clusters (designated the csb, csc, and csd loci), all encoding predicted glycosyltransferases. The csb locus contains the csbA, csbB, and csbC genes and is associated with a capsule that is a polymer of [6)-α-GlcpNAc-(1→5)-β-(8-OAc)Kdop-(2→] (type b). The csc locus contains the cscA, cscB, and cscC genes and is associated with a capsule that is a polymer of [3)-β-Ribf-(1→2)-β-Ribf-(1→2)-β-Ribf-(1→4)-β-Kdop-(2→] (type c). The csd locus contains the csdA, csdB, and csdC genes and is associated with a capsule that is a polymer of [P-(O→3)[β-Galp-(1→4)]-β-GlcpNAc-(1→3)-α-GlcpNAc-1-] (type d). Introduction of the csa, csb, csc, and csd loci into strain KK01Δcsa, a strain 269–492 derivative that lacks the native csaA gene, was sufficient to produce the type a capsule, type b capsule, type c capsule, and type d capsule, respectively, indicating that these loci are solely responsible for determining capsule type in K. kingae. Further analysis demonstrated that 96% of the invasive isolates express either the type a or type b capsule and that a disproportionate percentage of carrier isolates express the type c or type d capsule. These results establish that there are at least four structurally distinct K. kingae capsule types and suggest that capsule type plays an important role in promoting K. kingae invasive disease. PMID:27760194

  2. Floating capsules containing alginate-based beads of salbutamol sulfate: In vitro-in vivo evaluations.

    Science.gov (United States)

    Malakar, Jadupati; Datta, Prabir Kumar; Purakayastha, Saikat Das; Dey, Sanjay; Nayak, Amit Kumar

    2014-03-01

    The present study deals with the development and evaluations of stomach-specific floating capsules containing salbutamol sulfate-loaded oil-entrapped alginate-based beads. Salbutamol sulfate-loaded oil-entrapped beads were prepared and capsulated within hard gelatin capsules (size 1). The effects of HPMC K4M and potato starch weight masses on drug encapsulation efficiency (DEE) of beads and cumulative drug release at 10h (R10 h) from capsules was analyzed by 3(2) factorial design. The optimization results indicate increasing of DEE in the oil-entrapped beads and decreasing R10 h from capsules with increment of HPMC K4M and potato starch weight masses. The optimized formulation showed DEE of 70.02 ± 3.16% and R10 h of 56.96 ± 2.92%. These capsules showed floatation over 6h and sustained drug release over 10h in gastric pH (1.2). In vivo X-ray imaging study of optimized floating capsules in rabbits showed stomach-specific gastroretention over a prolonged period.

  3. Fabrication of the Supplemental Surveillance Capsules to Construct the Data of High-dose Irradiation Embrittlement

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Young Ki; Maeng, Young Jae; Kim, Kyung Sik; Lim, Mi Joung; Yoo, Choon Sung; Kim, Byoung Chul [Korea Reactor Integrity Surveillance Technology, Daejeon (Korea, Republic of)

    2015-10-15

    In order to monitor the neutron irradiation embrittlement of the reactor vessel material, the surveillance program should be implemented during the reactor operation through the plant life. This surveillance program requires the surveillance capsules which contain the various test specimens, thermal monitors, and neutron dosimeters. For PWRs in Korea, total six surveillance capsules are installed before plant operation and are programmed to be withdrawn and tested periodically in accordance with the surveillance program. The surveillance capsules are typically installed in the downcomer region and are located closer to the reactor core than the vessel wall in order to get more accelerated embrittlement characteristics of the vessel material. The supplemental surveillance capsules were fabricated to obtain the data of high-dose irradiation embrittlement. All test specimens in the capsules were made with the archive material of Hanbit Units 3 and 4. The supplemental capsules were designed to have the same outside dimensions as the capsules of Hanbit Unit 1 and were installed in Hanbit Unit 1. The withdrawal schedule will be calculated.

  4. Noncontact optical measurement of lens capsule thickness ex vivo

    Science.gov (United States)

    Ziebarth, Noel M.; Manns, Fabrice; Uhlhorn, Stephen; Parel, Jean-Marie

    2004-07-01

    Purpose: To design a non-contact optical system to measure lens capsule thickness in cadaver eyes. Methods: The optical system uses a 670nm laser beam delivered to a single-mode fiber coupler. The output of the fiber coupler is focused onto the tissue using an aspheric lens (NA=0.68) mounted on a motorized translation stage. Light reflected from the sample is collected by the fiber coupler and sent to a silicon photodiode connected to a power meter. Peaks in the power signal are detected when the focal point of the aspheric lens coincides with the capsule boundaries. The capsule thickness is proportional to the distance between successive peaks. Anterior and posterior lens capsule thickness measurements were performed on 13 human, 10 monkey, and 34 New Zealand white rabbit lenses. The cadaver eyes were prepared for optical measurements by bonding a PMMA ring on the sclera. The posterior pole was sectioned, excess vitreous was removed, and the eye was placed on a Teflon slide. The cornea and iris were then sectioned. After the experiments, the lenses were excised, placed in 10% buffered formalin, and prepared for histology. Results: Central anterior lens capsule thickness was 9.4+/-2.9μm (human), 11.2+/-6.6μm (monkey), and 10.3+/-3.6μm (rabbit) optically and 14.9+/-1.6μm (human), 17.7+/-4.9μm (monkey), and 12.6+/-2.3μm (rabbit) histologically. The values for the central posterior capsule were 9.4+/-2.9μm (human), 6.6+/-2.5μm (monkey), and 7.9+/-2.3μm (rabbit) optically and 4.6+/-1.4μm (human), 4.5+/-1.2μm (monkey), and 5.7+/-1.7μm (rabbit) histologically. Conclusions: This study demonstrates that a non-contact optical system can successfully measure lens capsule thickness in cadaver eyes.

  5. 喷水推进器进水流道参数化设计方法%Research on the parametric design of an inlet duct found in a marine waterjet

    Institute of Scientific and Technical Information of China (English)

    丁江明; 王永生

    2011-01-01

    为了提高喷水推进器进水流道的设计水平,改善其水动力性能、缩短设计周期、降低设计费用,研究了进水流道的参数化设计方法.在该方法中,进水流道的三维几何结构采用11个动态关联的控制参数定量描述.改变这些控制参数的值可自动调整流道的三维空间形状,实现流道几何的快速建模.在此基础上,利用计算流体力学方法对进水流道及船尾流场进行数值计算,用进水流道的出流均匀度、流动分离程度、空化程度、流动损失程度以及变工况适用性等多项指标对进水流道的流体动力性能进行综合评估.流道三维几何结构的参数化建模和综合流体动力性能的数值模拟这2个过程迭代运用,可实现进水流道的优质、快速设计.%In order to satisfactorily design an inlet duct found in marine waterjets in a way that economically uses time and money, a parametric design method was investigated in this article. The 3-D geometry of the inlet duct was characterized and created by eleven governing parameters which were incident with one another. Its shape could be modified automatically by turning the value of the governing parameters. The viscous flow in regions around the inlet duct and stern was simulated by means of a computational fluid dynamics code. The hydrodynamic performance of the inlet duct can be evaluated in the round according to flow uniformity at the duct outlet, flow separation, cavitations, flow loss inside the duct, and the applicability to various working conditions. Multiple iterations between the parametric modification of the geometry and CFD simulation of the flow field can quickly result in an excellent inlet duct design.

  6. Research on modular and parametric design based on knowledge engineering for cable protection product%基于知识工程的电缆保护产品模块参数化设计研究

    Institute of Scientific and Technical Information of China (English)

    刘燕华; 沈景凤; 仲梁维; 廖辉

    2014-01-01

    为了缩短大规模定制产品的设计周期及降低开发成本,解决工程经验的重用问题,提出了一种新型的电缆保护产品快速设计方法。将知识工程与计算机辅助设计技术相结合,并基于产品模块化技术和实例推理技术,实现了电缆保护产品的系列化、标准化和通用化,构建了该产品的快速模块参数化设计系统。经实例验证,该系统明显缩短了电缆保护产品的开发周期,提高了企业产品的开发效率。%In order to shorten the design cycle of mass customization product ,reduce development costs and solve the problem of the reuse of engineering experience ,a new design method was proposed to be applied to cable protection product .Combining with Knowledge-Based Engineering ( KBE) and computer aided design technology ,the method which is based on the product modular-ization technique and case-based reasoning technology realizes serialization ,standardized and generalization of the cable protection of products and constructs the rapid module and parametric design system .The system is demonstrated to cut short the design cy-cle of cable protection product obviously and improve product development efficiency with specific example .

  7. Intrauterine fertilization capsules--a clinical trial

    DEFF Research Database (Denmark)

    Lenz, S; Lindenberg, S; Sundberg, K

    1991-01-01

    chorionic gonadotropin. Oocytes were collected by ultrasonically guided transvaginal aspiration, and spermatozoa were prepared by swim-up technique. The gametes were placed in agar capsules 4 hr after oocyte collection, and the capsules were introduced to the uterine fundus using an insertion tube...

  8. The future of wireless capsule endoscopy

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    We outline probable and possible developments with wireless capsule endoscopy. It seems likely that capsule endoscopy will become increasingly effective in diagnostic gastrointestinal endoscopy. This will be attractive to patients especially for cancer or varices detection because capsule endoscopy is painless and is likely to have a higher take up rate compared to conventional colonoscopy and gastroscopy. Double imager capsules with increased frame rates have been used to image the esophagus for Barrett's and esophageal varices. The image quality is not bad but needs to be improved if it is to become a realistic substitute for flexible upper and lower gastrointestinal endoscopy. An increase in the frame rate, angle of view, depth of field, image numbers, duration of the procedure and improvements in illumination seem likely. Colonic, esophageal and gastric capsules will improve in quality, eroding the supremacy of flexible endoscopy, and become embedded into screening programs. Therapeutic capsules will emerge with brushing, cytology, fluid aspiration, biopsy and drug delivery capabilities. Electrocautery may also become possible. Diagnostic capsules will integrate physiological measurements with imaging and optical biopsy, and immunologic cancer recognition. Remote control movement will improve with the use of magnets and/or electrostimulation and perhaps electromechanical methods. External wireless commands will influence capsule diagnosis and therapy and will increasingly entail the use of real-time imaging. However, it should be noted that speculations about the future of technology in any detail are almost always wrong.

  9. How helpful is capsule endoscopy to surgeons?

    Institute of Scientific and Technical Information of China (English)

    Osman Ersoy; Bulent Sivri; Yusuf Bayraktar

    2007-01-01

    Capsule endoscopy is a new technology that, for the first time, allows complete, non-invasive endoscopic imaging of the small bowel. The efficacy of capsule endoscopy in the diagnosis of suspected small bowel diseases has been established. Important applications for surgeons include observations of obscure gastrointestinal bleeding and small bowel neoplasms.

  10. Optimization of linear parametric circuits by the control of stability

    Directory of Open Access Journals (Sweden)

    Yu. I. Shapovalov

    2013-07-01

    Full Text Available Introduction. A brief description of the symbolic frequency method for linear parametric circuit analysis is adduced. In particular it comes to parametric transfer functions and assessment of asymptotic stability of such circuits. The formulation of optimization task. The objective function formation is done via two functions - the function of goal defined by desirable circuit characteristics (goal of optimization and function characteristics of circuit defined by the selected values of the varied parameters during optimization of electrical circuit characteristics. The coincidence degree of these two functions is objective function which is formed on their basis by the chosen method. The procedure of optimization. The solution of optimization task is determining the values с0* and m* that provide minimum value of objective function, satisfy the condition of circuit stability and conditions of physical parametric element realizability Example. There is example of single-circuit parametric amplifier optimization using the objective function based on the calculation of parametric circuit transfer function with a symbolic representation of the parametric capacity parameters. Conclusions. Frequency symbolic analysis method allows solving optimization task of parametric linear circuits designing in the frequency domain based on use of the frequency symbolic transfer functions which are approximated by trigonometric polynomials of Fourier, particularly in complex form.

  11. Parametric analysis as a methodical approach that facilitates the exploration of the creative space in low-energy and zero-energy design projects

    DEFF Research Database (Denmark)

    Hansen, Hanne Tine Ring; Knudstrup, Mary-Ann

    2008-01-01

    -energy or zero-energy building design. The paper discusses professional differences between two of the main actors involved in integrated design processes; engineers and architects, as well as a methodical approach to investigation and delimitation of the creative space of a specific project. The paper......Most – if not all - methodical approaches found in literature that describe the creation of environmentally sustainable architecture agree on the importance of inter-disciplinarity and the early integration of building system strategies and the importance of the comfort of the user. Today most...... people agree that it is important, or even crucial, that architects and engineers cooperate from the beginning of the process. But there is still no consensus about how or when this should happen. This paper discusses how inter-disciplinarity can be achieved in an integrated design process aiming at low...

  12. 基于 UG 图形模板的渐开线花键轴滚轧轮参数化设计%Parametric Design of Rolling Wheel of Involute Spline Shaft Based on UG Graphical Templates

    Institute of Scientific and Technical Information of China (English)

    王柯智; 余小鲁

    2014-01-01

    The authors used UG to parametric modeling the rolling wheel of involute spline shaft .The basic parame‐ters of the rolling wheel were determined by the parameters of the spline shaft ,then the spline shaft parameters were associated with the 3D model of the rolling wheel .By modifying the keys ,modulus ,pressure angle and other pa‐rameters of spline shaft ,three‐dimensional model of rolling wheel was obtained ,which improves the design efficien‐cy and reusability of design ideas greatly .%运用UG软件对渐开线花键轴滚轧轮进行参数化建模,通过花键轴的参数确定滚轧轮基本参数,将花键轴参数与滚轧轮三维模型关联起来。通过修改花键轴的键数、模数、压力角等参数,建立所需滚轧轮的三维模型,大大提高了设计效率以及设计思路的可重用性。

  13. Parametric Timing Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Vivancos, E; Healy, C; Mueller, F; Whalley, D

    2001-05-09

    Embedded systems often have real-time constraints. Traditional timing analysis statically determines the maximum execution time of a task or a program in a real-time system. These systems typically depend on the worst-case execution time of tasks in order to make static scheduling decisions so that tasks can meet their deadlines. Static determination of worst-case execution times imposes numerous restrictions on real-time programs, which include that the maximum number of iterations of each loop must be known statically. These restrictions can significantly limit the class of programs that would be suitable for a real-time embedded system. This paper describes work-in-progress that uses static timing analysis to aid in making dynamic scheduling decisions. For instance, different algorithms with varying levels of accuracy may be selected based on the algorithm's predicted worst-case execution time and the time allotted for the task. We represent the worst-case execution time of a function or a loop as a formula, where the unknown values affecting the execution time are parameterized. This parametric timing analysis produces formulas that can then be quickly evaluated at run-time so dynamic scheduling decisions can be made with little overhead. Benefits of this work include expanding the class of applications that can be used in a real-time system, improving the accuracy of dynamic scheduling decisions, and more effective utilization of system resources. This paper describes how static timing analysis can be used to aid in making dynamic scheduling decisions. The WCET of a function or a loop is represented as a formula, where the values affecting the execution time are parameterized. Such formulas can then be quickly evaluated at run-time so dynamic scheduling decisions can be made when scheduling a task or choosing algorithms within a task. Benefits of this parametric timing analysis include expanding the class of applications that can be used in a real

  14. Non-parametric versus parametric methods in environmental sciences

    Directory of Open Access Journals (Sweden)

    Muhammad Riaz

    2016-01-01

    Full Text Available This current report intends to highlight the importance of considering background assumptions required for the analysis of real datasets in different disciplines. We will provide comparative discussion of parametric methods (that depends on distributional assumptions (like normality relative to non-parametric methods (that are free from many distributional assumptions. We have chosen a real dataset from environmental sciences (one of the application areas. The findings may be extended to the other disciplines following the same spirit.

  15. Capsule collection for women's plus-size clothing brand

    OpenAIRE

    Vähäkangas, Oona

    2016-01-01

    The objective of the thesis was to design a capsule collection for women’s plus-size clothing brand called annascholz Ltd. The thesis was based on a design studio internship period that was carried out by the author at the company during summer 2016 and knowledge gained during that time. The thesis consisted of two parts: the first part was the research part and the second the practice-based design part. In the research part more information was gained of the target group by reading studie...

  16. Parametric scramjet analysis

    Science.gov (United States)

    Choi, Jongseong

    The performance of a hypersonic flight vehicle will depend on existing materials and fuels; this work presents the performance of the ideal scramjet engine for three different combustion chamber materials and three different candidate fuels. Engine performance is explored by parametric cycle analysis for the ideal scramjet as a function of material maximum service temperature and the lower heating value of jet engine fuels. The thermodynamic analysis is based on the Brayton cycle as similarly employed in describing the performance of the ramjet, turbojet, and fanjet ideal engines. The objective of this work is to explore material operating temperatures and fuel possibilities for the combustion chamber of a scramjet propulsion system to show how they relate to scramjet performance and the seven scramjet engine parameters: specific thrust, fuel-to-air ratio, thrust-specific fuel consumption, thermal efficiency, propulsive efficiency, overall efficiency, and thrust flux. The information presented in this work has not been done by others in the scientific literature. This work yields simple algebraic equations for scramjet performance which are similar to that of the ideal ramjet, ideal turbojet and ideal turbofan engines.

  17. Experimental Investigation of the Spiral Structure of a Magnetic Capsule Endoscope

    Directory of Open Access Journals (Sweden)

    Wanan Yang

    2016-06-01

    Full Text Available Fitting a wireless capsule endoscope (WCE with a navigation feature can maximize its functional benefits. The rotation of a spiral-type capsule can be converted to translational motion. The study investigated how the spiral structure and rotational speed affected the capsule’s translation speed. A hand-held instrument, including two permanent magnets, a stepper motor, a controller and a power supplier, were designed to generate rotational magnetic fields. The surfaces of custom-built permanent magnet rings magnetized radially were mounted in spiral lines with different lead angles and diameters, acting as mock-up capsules. The experimental results demonstrate that the rotational speed of the magnetic field and the spiral have significant effects on the translational speed of a capsule. The spiral line with a larger lead angle and the rotating magnetic field with a higher speed can change the capsule’s rotation into a translational motion more efficiently in the intestine.

  18. Thermal lensing in silver gallium selenide parametric oscillator crystals.

    Science.gov (United States)

    Marquardt, C L; Cooper, D G; Budni, P A; Knights, M G; Schepler, K L; Dedomenico, R; Catella, G C

    1994-05-20

    We performed an experimental investigation of thermal lensing in silver gallium selenide (AgGaSe(2)) optical parametric oscillator crystals pumped by a 2-µm laser at ambient temperature. We determined an empirical expression for the effective thermal focusing power in terms of the pump power, beam diameter, crystal length, and absorption coefficient. This relation may be used to estimate average power limitations in designing AgGaSe(2) optical parametric oscillators. We also demonstrated an 18% slope efficiency from a 2-µm pumped AgGaSe(2) optical parametric oscillator operated at 77 K, at which temperature thermal lensing is substantially reduced because of an increase in the thermal conductivity and a decrease in the thermal index gradient dn/dT. Cryogenic cooling may provide an additional option for scaling up the average power capability of a 2-µm pumped AgGaSe(2) optical parametric oscillator.

  19. Modeling Interconnect Variability Using Efficient Parametric Model Order Reduction

    CERN Document Server

    Li, Peng; Li, Xin; Pileggi, Lawrence T; Nassif, Sani R

    2011-01-01

    Assessing IC manufacturing process fluctuations and their impacts on IC interconnect performance has become unavoidable for modern DSM designs. However, the construction of parametric interconnect models is often hampered by the rapid increase in computational cost and model complexity. In this paper we present an efficient yet accurate parametric model order reduction algorithm for addressing the variability of IC interconnect performance. The efficiency of the approach lies in a novel combination of low-rank matrix approximation and multi-parameter moment matching. The complexity of the proposed parametric model order reduction is as low as that of a standard Krylov subspace method when applied to a nominal system. Under the projection-based framework, our algorithm also preserves the passivity of the resulting parametric models.

  20. A New Concept for Magnetic Capsule Colonoscopy based on an Electromagnetic System

    Directory of Open Access Journals (Sweden)

    Gioia Lucarini

    2015-03-01

    Full Text Available Traditional endoscopy based on flexible endoscopes is reliable and effective, but poorly tolerated by patients; it also requires extended training by physicians. In order to reduce the invasiveness of these procedures, wireless passive capsule endoscopy has been proposed and clinically used during the past decade. A capsule endoscope with an active locomotion mechanism is desirable for carrying out controllable interactive procedures that are normally not possible using passive devices. Due to many difficulties in embedding actuators in swallowable devices, many researchers and companies have adopted an external magnetic field actuation solution. Magnetic resonance modified systems or permanent magnets are used to manoeuvre capsules remotely; however, both these cases present some limitations: magnetic resonance systems are bulky and expensive and permanent magnets are intrinsically unstable to control, and it is impossible to switch them off. Within this framework, the authors present the design and assessment of a magnetic system for endoscopic capsules based on an electromagnetic approach. In particular, the use of a single electromagnet was proposed and investigated: magnetic attraction, locomotion forces and magnetic torques were modelled for guaranteeing the reliable navigation of the capsule and based on these specifications, an electromagnet was designed, developed and experimentally evaluated. The results demonstrated the feasibility of the proposed approach for active locomotion capsule endoscopy.

  1. Developing a 1D ``like'' performance basecamp for beryllium capsule implosions

    Science.gov (United States)

    Kline, John; Yi, Austin; Loomis, Eric; Simakov, Andrei; Kyrala, George; Wilson, Doub; Dewald, Eddie; Ralph, Joe; Strozzi, David

    2016-10-01

    Experiments with Beryllium capsules in high density gas filled targets showed little difference in performance with respect to CH or HDC capsules. The hypothesis for the lack of performance difference is attributed to poor control of symmetry based on work by Clark et al. Going forward, the goal is to develop a target design that enables better comparisons between the performance of Be capsules and other ablators, as well as with simulations. To develop a platform in which Be capsules maximize performance with respect to 1D calculations, we have increased the case-to-capsule ratio and reduced the hohlraum drive. The stability properties of beryllium are expected to be accentuated at lower radiation temperature drives compared with other ablators. Experiments have been carried out with case-to-capasule ratio of 3.1 and 4.3. Results from these experiments are being used to develop an optimized case-to-capsule ratio to achieve controllable symmetric implosions with maximum 1D like performance. This presentation will focus on how results of the experiments are used to design the next series of optimized experiments..

  2. Planar Parametrization in Isogeometric Analysis

    DEFF Research Database (Denmark)

    Gravesen, Jens; Evgrafov, Anton; Nguyen, Dang-Manh;

    2012-01-01

    Before isogeometric analysis can be applied to solving a partial differential equation posed over some physical domain, one needs to construct a valid parametrization of the geometry. The accuracy of the analysis is affected by the quality of the parametrization. The challenge of computing...... and maintaining a valid geometry parametrization is particularly relevant in applications of isogemetric analysis to shape optimization, where the geometry varies from one optimization iteration to another. We propose a general framework for handling the geometry parametrization in isogeometric analysis and shape...... are suitable for our framework. The non-linear methods we consider are based on solving a constrained optimization problem numerically, and are divided into two classes, geometry-oriented methods and analysis-oriented methods. Their performance is illustrated through a few numerical examples....

  3. High-Density Carbon (HDC) Ablator for NIC Ignition Capsules

    Science.gov (United States)

    Ho, D.; Haan, S.; Salmonson, J.; Milovich, J.; Callahan, D.

    2012-10-01

    HDC ablators show high performance based on simulations, despite the fact that the shorter pulses for HDC capsules result in higher M-band radiation compared to that for plastic capsules. HDC capsules have good 1-D performance because HDC has relatively high density (3.5 g/cc), which results in a thinner ablator that absorbs more radiation. HDC ablators have good 2-D performance because the ablator surface is more than an order-of-magnitude smoother than Be or plastic ablators. Refreeze of the ablator near the fuel region can be avoided by appropriate dopant placement. Here we present two HDC ignition designs doped with W and Si. For the design with maximum W concentration of 1.0 at% (and respectively with maximum Si concentration of 2.0 at%): peak velocity = 0.395 (0.397) mm/ns, mass weighted fuel entropy = 0.463 (0.469) kJ/mg/eV, peak core hydrodynamic stagnation pressure = 690 (780) Gbar, and yield = 17.3 (20.2) MJ. 2-D simulations show that yield is close to 80% YoC even with 2.5x of nominal surface roughness on all surfaces. The clean fuel fraction is about 75% at peak velocity. Doping HDC with the required concentration of W and Si is in progress. A first undoped HDC Symcap is scheduled to be fielded later this year.

  4. Design, construction, operation and evaluation of a prototype anthracite culm combustion boiler unit. Facility test plan: startup and shakedown, parametric studies and long term operation

    Energy Technology Data Exchange (ETDEWEB)

    1981-06-01

    This proposed performance study is to be performed in the anthracite culm prototype boiler located at Paxinos, Pennsylvania. The boiler is designed to produce 23,400 lb/hr of steam of 200 psig. Effects of operating variables on combustion efficiency, sulfur retention, erosion and corrosion will be analyzed during the runs. The boiler will be operated to determine its technical, economic and environmental performance and to project the viability of it for commercial operation. After the initial testing, the boiler performance will be evaluated over the long term operation.

  5. Hierarchical Geometric Constraint Model for Parametric Feature Based Modeling

    Institute of Scientific and Technical Information of China (English)

    高曙明; 彭群生

    1997-01-01

    A new geometric constraint model is described,which is hierarchical and suitable for parametric feature based modeling.In this model,different levels of geometric information are repesented to support various stages of a design process.An efficient approach to parametric feature based modeling is also presented,adopting the high level geometric constraint model.The low level geometric model such as B-reps can be derived automatically from the hig level geometric constraint model,enabling designers to perform their task of detailed design.

  6. Parametric Coding of Stereo Audio

    Directory of Open Access Journals (Sweden)

    Erik Schuijers

    2005-06-01

    Full Text Available Parametric-stereo coding is a technique to efficiently code a stereo audio signal as a monaural signal plus a small amount of parametric overhead to describe the stereo image. The stereo properties are analyzed, encoded, and reinstated in a decoder according to spatial psychoacoustical principles. The monaural signal can be encoded using any (conventional audio coder. Experiments show that the parameterized description of spatial properties enables a highly efficient, high-quality stereo audio representation.

  7. [Karyosphere capsule in Tribolium castaneum oocytes].

    Science.gov (United States)

    Batalova, F M; Bogoliubov, D S

    2013-01-01

    Structure and composition of the karyosphere (karyosome) capsule were studied in the oocytes of a laboratory insect, Tribolium castaneum, with the use of electron microscopy and immunoelectron cytochemistry. Basing on the study of nuclear structure dynamics, we distinguished 8 stages that characterize the period of oocyte growth. At the diplotene stage, T. castaneum oocyte chromosomes conjoin early into a compact karyosphere, but a significant chromatin condensation does not occur. The process of karyosphere formation is accompanied by the development of an extensive extrachromosome capsule surrounding chromatin. The capsule consists of a material of different morphological types. Significant molecular components of the T. castaneum karyosphere capsule are represented by the proteins of nuclear matrix including F-actin and lamin B. Besides the structural proteins, the Sm proteins of small nuclear (sn) RNPs and mature 2,2,7-trimethyl guanosine (TMG) 5'-capped snRNAs are revealed immunocytochemically in the karyosphere capsule. The obtained data can form a basis for further expansion of ideas on the functions of the karyosphere capsule as a specialized extrachromosomal nuclear domain of the oocytes. We believe that the T. castaneum karyosphere capsule plays not only a structural role, but may be involved directly in the processes related to gene expression.

  8. [Evaluation of nopal capsules in diabetes mellitus].

    Science.gov (United States)

    Frati Munari, A C; Vera Lastra, O; Ariza Andraca, C R

    1992-01-01

    To find out if commercial capsules with dried nopal (prickle-pear cactus, Opuntia ficus indica may have a role in the management of diabetes mellitus, three experiments were performed: 30 capsules where given in fasting condition to 10 diabetic subjects and serum glucose was measured through out 3 hours; a control test was performed with 30 placebo capsules. OGTT with previous intake of 30 nopal or placebo capsules was performed in ten healthy individuals. In a crossover and single blinded study 14 diabetic patients withdrew the oral hypoglycemic treatment and received 10 nopal or placebo capsules t.i.d. during one week; serum glucose, cholesterol and tryglycerides levels were measured before and after each one-week period. Five healthy subjects were also studied in the same fashion. Opuntia capsules did not show acute hypoglycemic effect and did not influence OGTT. In diabetic patients serum glucose, cholesterol and tryglycerides levels did not change with Opuntia, but they increased with placebo (P nopal, while cholesterol and triglycerides decreased (P < 0.01 vs. placebo). The intake of 30 Opuntia capsules daily in patients with diabetes mellitus had a discrete beneficial effect on glucose and cholesterol. However this dose is unpractical and at present it is not recommended in the management of diabetes mellitus.

  9. A Parametric Approach to IIR Digital Filter Design%一种设计ⅡR数字滤波器的参数化方法

    Institute of Scientific and Technical Information of China (English)

    徐红; 李刚; 黄朝耿; 叶丰

    2012-01-01

    Based on a continuous-time state-space structure and the generalized bilinear transformation(GBT),a parameterization for IIR digital filter design is proposed.The cost function can be minimised without stability monitoring because the corresponding stability region is the entire parameter space.Simulation shows that the performance of the filters obtained with the proposed approach is better than that of those designed with an existing one in terms of passband ripple,stopband attenuation and group delay.%基于连续时间状态空间结构和广义双线性变换,提出了一种设计无限冲激响应(ⅡR)数字滤波器的参数化方法.优点是稳定区域包含了整个参数空间,因此可以采用无约束优化方法.给出了仿真实例,并与已有的设计方法进行了比较,其通带波动、阻带衰减、群迟延等性能更为优越.

  10. The Type a and Type b Polysaccharide Capsules Predominate in an International Collection of Invasive Kingella kingae Isolates.

    Science.gov (United States)

    Porsch, Eric A; Starr, Kimberly F; Yagupsky, Pablo; St Geme, Joseph W

    2017-01-01

    Kingella kingae is an encapsulated Gram-negative bacterium and an important etiology of osteoarticular infections in young children. A recent study examining a diverse collection of carrier and invasive K. kingae isolates from Israel revealed four distinct polysaccharide capsule types. In this study, to obtain a global view of K. kingae capsule type diversity, we examined an international collection of isolates using a multiplex PCR approach. The collection contained all four previously identified capsule types and no new capsule types. Over 95% of invasive isolates in the collection were type a or type b, similar to the findings in Israel. These results suggest that the type a and type b polysaccharide capsules may have enhanced pathogenic properties or may mark clonal groups of strains with specific virulence genes. In addition, they raise the possibility that a vaccine containing the type a and type b capsules might be an effective approach to preventing K. kingae disease. IMPORTANCEKingella kingae has emerged as a significant cause of septic arthritis, osteomyelitis, and bacteremia in young children. A recent study examining a diverse collection of K. kingae isolates from Israel revealed four different polysaccharide capsule types in this species, designated types a to d. To determine the global distribution of K. kingae capsule types, we assembled and capsule typed an international collection of K. kingae isolates. The findings reported here show that the type a and type b capsules represent >95% of the invasive isolates, similar to the Israeli isolate collection, suggesting that a polysaccharide-based vaccine targeting these two capsules could be an attractive approach to prevent K. kingae disease.

  11. 蜗轮蜗杆参数化设计及运动仿真%Parametric Design and Computer Simulation of Worm Gear and Worm

    Institute of Scientific and Technical Information of China (English)

    刘其兵; 严红

    2012-01-01

    在Pro/E环境下,以蜗轮蜗杆零件的三维建模为基础,将变参设计巧妙融入到零件三维实体的创建过程中,通过生成的可视化变参对话框,实现蜗轮蜗杆的快速建模,在此基础上,对快速建模的蜗轮蜗杆进行了虚拟装配和运动仿真.%In Pro/E environment, based on the worm gear and worm 3D solid model, putting the changeable parameters design were put in the part 3D model creating procedure. The rapid modeling of worm gear and worm were realized by generating visual variable parameters dialog box. On this basis,the virtual assembly and motion simulation were made for rapid modeling of worm gear and worm.

  12. Tag gas capsule with magnetic piercing device

    Science.gov (United States)

    Nelson, Ira V.

    1976-06-22

    An apparatus for introducing a tag (i.e., identifying) gas into a tubular nuclear fuel element. A sealed capsule containing the tag gas is placed in the plenum in the fuel tube between the fuel and the end cap. A ferromagnetic punch having a penetrating point is slidably mounted in the plenum. By external electro-magnets, the punch may be caused to penetrate a thin rupturable end wall of the capsule and release the tag gas into the fuel element. Preferably the punch is slidably mounted within the capsule, which is in turn loaded as a sealed unit into the fuel element.

  13. Required Be Capsule Strength For Room Temperature Transport

    Energy Technology Data Exchange (ETDEWEB)

    Cook, B

    2005-03-21

    The purpose of this memo is to lay out the criteria for the Be capsule strength necessary for room temperature transport. Ultimately we will test full thickness capsules by sealing high pressures inside, but currently we are limited to both thinner capsules and alternative measures of capsule material strength.

  14. 蜗轮蜗杆参数化设计及运动仿真%Parametric Design and Simulation of Worm Gear and Worm

    Institute of Scientific and Technical Information of China (English)

    刘其兵; 严红

    2012-01-01

    In Pro/E environment, based on the worm gear and worm 3D solid molding, putting the changeable parameter design in the part 3D model creating procedure. By generating visual variable parameters dialog box, realize the rapid modeling of worm gear and worm. On this basis, finished rapid modeling of worm gear and worm of virtual assembly and motion simulation, laid the foundation for the follow - up study of the worm and worm gear.%在Pro/E环境下,以蜗轮蜗杆零件的三维建模为基础,将变参设计巧妙融入到零件三维实体的创建过程中,通过生成的可视化变参对话框,实现蜗轮蜗杆的快速建模,在此基础上,对快速建模的蜗轮蜗杆进行了虚拟装配和运动仿真,为蜗轮蜗杆机构的后续研究奠定了基础.

  15. Building information modeling based on intelligent parametric technology

    Institute of Scientific and Technical Information of China (English)

    ZENG Xudong; TAN Jie

    2007-01-01

    In order to push the information organization process of the building industry,promote sustainable architectural design and enhance the competitiveness of China's building industry,the author studies building information modeling (BIM) based on intelligent parametric modeling technology.Building information modeling is a new technology in the field of computer aided architectural design,which contains not only geometric data,but also the great amount of engineering data throughout the lifecycle of a building.The author also compares BIM technology with two-dimensional CAD technology,and demonstrates the advantages and characteristics of intelligent parametric modeling technology.Building information modeling,which is based on intelligent parametric modeling technology,will certainly replace traditional computer aided architectural design and become the new driving force to push forward China's building industry in this information age.

  16. Parametric Design and Experimental Study of Damping Holey Spur Gear%减振孔穴直齿轮的参数设计及试验研究

    Institute of Scientific and Technical Information of China (English)

    刘琳辉; 方宗德; 田海波; 杨小芳

    2011-01-01

    Drilling on gears could reduce the vibration effectively. The finite element models of a pair of spur gears are studied for stress calculation. The stress data is fitted with quadratic polynomial by response surface method and least squares method. The design values of holes' parameters are presented through the optimization of minimizing the maximum stress. The gear samples are produced and the contrast test between holey spur gear and common spur gear is applied on the gear closed test bench. The test results imply that drilling on gears would damp the vibration of gear pair and can be applied extensively.%齿轮上钻孔能够有效地降低齿轮传动的振动水平.针对某型直齿圆柱齿轮的有限元模型进行应力计算,将计算数据用响应面法和最小二乘原理拟合成二次多项式,再以最大应力最小化为目标进行优化求解,得到孔穴参数的设计值,并加工了齿轮样件;在齿轮封闭试验台上完成了孔穴齿轮与普通齿轮的对比试验.试验结果表明,孔穴结构可以降低齿轮副的振动,具有广阔的应用前景.

  17. Therapeutic Capsule Endoscopy: Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Mahdi Rasouli

    2011-01-01

    Full Text Available The increasing demand for non-invasive (or less-invasive monitoring and treatment of medical conditions has attracted both physicians and engineers to work together and investigate new methodologies. Wireless capsule endoscopy is a successful example of such techniques which has become an accepted routine for diagnostic inspection of the gastrointestinal tract. This method offers a non-invasive alternative to traditional endoscopy and provides the opportunity for exploring distal areas of the small intestine which are otherwise not accessible. Despite these advantages, wireless capsule endoscopy is still limited in functionality compared to traditional endoscopy. Wireless capsule endoscopes with advanced functionalities, such as biopsy or drug delivery, are highly desirable. In this article, the current status of wireless capsule endoscopy is reviewed together with some of its possible therapeutic applications as well as the existing challenges.

  18. Technological Design and Parametric Analysis of Annular Aerated Drilling%环空充气钻井工艺设计及参数分析

    Institute of Scientific and Technical Information of China (English)

    窦亮彬; 李根生; 沈忠厚; 吴春方; 刘文旭

    2013-01-01

    The gas phase distribution of traditional parasitic tube aerated drilling tool is uneven in annulus. Therefore, a new type of parasitic tube aerated drilling tool with even distribution of annular gas was designed. According to heat transfer theory, thermodynamic theory and the theory of vertical gas liquid two-phase pipe flow, the optimization analysis of the parameters of the annular aeration technology was conducted considering the variation of injection gas physical property with shaft temperature and pressure. The findings show that annular pressure first decreases with the increase of gas injection rate and then gradually increases. The gas flowrate slightly larger than that at the critical point is taken as the gas injection rate. The variation amplitude of annular pressure in the static control zone is noticeably greater than wellhead back pressure variation. The annular pressure becomes sensitive. In the friction control zone with the variation of wellhead back pressure, the variation amplitude of annular pressure is relatively small, getting milder and thus is easier to regulate.%针对传统寄生管充气钻井工具在环空中形成的气相分布不均匀的弊端,设计了一种新型环形气体均布寄生管充气钻井工具.根据传热学、热力学和垂直气液两相管流理论,考虑注入气体物性随井筒温度压力变化,对环空充气工艺参数进行优化分析.分析结果表明,环空压力随注气量增大先急剧降低后逐渐升高,注气量通常选择在稍大于临界点处对应的气体流量;在静压控制区环空压力变化幅度明显大于井口回压变化,环空压力变化敏感;在摩擦控制区随井口回压变化,环空压力变化幅度较小,更加缓和,易于调节.

  19. Semipermeable Capsules Wrapping a Multifunctional and Self-regulated Co-culture Microenvironment for Osteogenic Differentiation

    Science.gov (United States)

    Correia, Clara R.; Pirraco, Rogério P.; Cerqueira, Mariana T.; Marques, Alexandra P.; Reis, Rui L.; Mano, João F.

    2016-02-01

    A new concept of semipermeable reservoirs containing co-cultures of cells and supporting microparticles is presented, inspired by the multi-phenotypic cellular environment of bone. Based on the deconstruction of the “stem cell niche”, the developed capsules are designed to drive a self-regulated osteogenesis. PLLA microparticles functionalized with collagen I, and a co-culture of adipose stem (ASCs) and endothelial (ECs) cells are immobilized in spherical liquified capsules. The capsules are coated with multilayers of poly(L-lysine), alginate, and chitosan nano-assembled through layer-by-layer. Capsules encapsulating ASCs alone or in a co-culture with ECs are cultured in endothelial medium with or without osteogenic differentiation factors. Results show that osteogenesis is enhanced by the co-encapsulation, which occurs even in the absence of differentiation factors. These findings are supported by an increased ALP activity and matrix mineralization, osteopontin detection, and the up regulation of BMP-2, RUNX2 and BSP. The liquified co-capsules also act as a VEGF and BMP-2 cytokines release system. The proposed liquified capsules might be a valuable injectable self-regulated system for bone regeneration employing highly translational cell sources.

  20. Dynamics of nonspherical compound capsules in simple shear flow

    Science.gov (United States)

    Luo, Zheng Yuan; Bai, Bo Feng

    2016-10-01

    The dynamics of an initially ellipsoidal compound capsule in a simple shear flow is investigated numerically using a three-dimensional front-tracking finite-difference model. Membrane bending resistance is included based on Helfrich's energy function besides the resistances against shear deformation and area dilatation governed by the constitutive law of Skalak et al. In this paper, we focus specifically on how the presence of a spherical inner capsule and its size affects the characteristics and transition of various dynamical states of nonspherical compound capsules (i.e., the outer capsule). Significant differences in the dynamical characteristics are observed between compound capsules and homogeneous capsules in both qualitative and quantitative terms. We find the transition from swinging to tumbling can occur at vanishing viscosity mismatch through increasing the inner capsule size alone to a critical value regardless of the initial shape of the nonspherical compound capsule (i.e., prolate or oblate). Besides, for compound capsules with viscosity mismatch, the critical viscosity ratio for the swinging-to-tumbling transition remarkably decreases by increasing the inner capsule size. It is thus concluded that the inner capsule size is a key governing parameter of compound capsule dynamics apart from the capillary number, aspect ratio, and viscosity ratio that have been long identified for homogeneous capsules. Further, we discuss the mechanisms underlying the effects of the inner capsule on the compound capsule dynamics from the viewpoint of the effective viscosity of internal fluid and find that the effects of the inner capsule on compound capsule dynamics are qualitatively similar to that of increasing the internal viscosity on homogeneous capsule dynamics. However, in quantitative terms, the compound capsule cannot be viewed as a homogeneous capsule with higher viscosity as obvious inhomogeneity in fluid stress distribution is induced by the inner membrane.

  1. Parametric Verification of Weighted Systems

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Hansen, Mikkel; Mariegaard, Anders

    2015-01-01

    This paper addresses the problem of parametric model checking for weighted transition systems. We consider transition systems labelled with linear equations over a set of parameters and we use them to provide semantics for a parametric version of weighted CTL where the until and next operators ar...... finitely many iterations. To demonstrate the utility of our technique, we have implemented a prototype tool that computes the constraints on parameters for model checking problems.......This paper addresses the problem of parametric model checking for weighted transition systems. We consider transition systems labelled with linear equations over a set of parameters and we use them to provide semantics for a parametric version of weighted CTL where the until and next operators...... are themselves indexed with linear equations. The parameters change the model-checking problem into a problem of computing a linear system of inequalities that characterizes the parameters that guarantee the satisfiability. To address this problem, we use parametric dependency graphs (PDGs) and we propose...

  2. Multicutter machining of compound parametric surfaces

    Science.gov (United States)

    Hatna, Abdelmadjid; Grieve, R. J.; Broomhead, P.

    2000-10-01

    Parametric free forms are used in industries as disparate as footwear, toys, sporting goods, ceramics, digital content creation, and conceptual design. Optimizing tool path patterns and minimizing the total machining time is a primordial issue in numerically controlled (NC) machining of free form surfaces. We demonstrate in the present work that multi-cutter machining can achieve as much as 60% reduction in total machining time for compound sculptured surfaces. The given approach is based upon the pre-processing as opposed to the usual post-processing of surfaces for the detection and removal of interference followed by precise tracking of unmachined areas.

  3. Parametric uncertain identification of a robotic system

    Science.gov (United States)

    Angel, L.; Viola, J.; Hernández, C.

    2016-07-01

    This paper presents the parametric uncertainties identification of a robotic system of one degree of freedom. A MSC-ADAMS / MATLAB co-simulation model was built to simulate the uncertainties that affect the robotic system. For a desired trajectory, a set of dynamic models of the system was identified in presence of variations in the mass, length and friction of the system employing least squares method. Using the input-output linearization technique a linearized model plant was defined. Finally, the maximum multiplicative uncertainty of the system was modelled giving the controller desired design conditions to achieve a robust stability and performance of the closed loop system.

  4. TAGS 85/2N RTG Power for Viking Lander Capsule

    Science.gov (United States)

    1969-08-01

    Results of studies performed by Isotopes, Inc., Nuclear Systems Division, to optimize and baseline a TAGS 85/2N RTG for the Viking Lander Capsule prime electrical power source are presented. These studies generally encompassed identifying the Viking RTG mission profile and design requirements, and establishing a baseline RTG design consistent with these requirements.

  5. Application of QbD principles for the evaluation of empty hard capsules as an input parameter in formulation development and manufacturing.

    Science.gov (United States)

    Stegemann, Sven; Connolly, Paul; Matthews, Wayne; Barnett, Rodger; Aylott, Mike; Schrooten, Karin; Cadé, Dominique; Taylor, Anthony; Bresciani, Massimo

    2014-06-01

    Understanding the product and process variable on the final product performance is an essential part of the quality-by-design (QbD) principles in pharmaceutical development. The hard capsule is an established pharmaceutical dosage form used worldwide in development and manufacturing. The empty hard capsules are supplied as an excipient that is filled by pharmaceutical manufacturers with a variety of different formulations and products. To understand the potential variations of the empty hard capsules as an input parameter and its potential impact on the finished product quality, a study was performed investigating the critical quality parameters within and in between different batches of empty hard gelatin capsules. The variability of the hard capsules showed high consistency within the specification of the critical quality parameters. This also accounts for the disintegration times, when automatic endpoint detection was used. Based on these data, hard capsules can be considered as a suitable excipient for product development using QbD principles.

  6. Validity of Parametrized Quark Propagator

    Institute of Scientific and Technical Information of China (English)

    ZHUJi-Zhen; ZHOULi-Juan; MAWei-Xing

    2005-01-01

    Based on an extensively study of the Dyson-Schwinger equations for a fully dressed quark propagator in the “rainbow”approximation, a parametrized fully dressed quark propagator is proposed in this paper. The parametrized propagator describes a confining quark propagator in hadron since it is analytic everywhere in complex p2-plane and has no Lemmann representation. The validity of the new propagator is discussed by comparing its predictions on selfenergy functions A/(p2), Bl(p2) and effective mass M$(p2) of quark with flavor f to their corresponding theoretical results produced by Dyson-Schwinger equations. Our comparison shows that the parametrized quark propagator is a good approximation to the fully dressed quark propagator given by the solutions of Dyson-Schwinger equations in the rainbow approximation and is convenient to use in any theoretical calculations.

  7. Validity of Parametrized Quark Propagator

    Institute of Scientific and Technical Information of China (English)

    ZHU Ji-Zhen; ZHOU Li-Juan; MA Wei-Xing

    2005-01-01

    Based on an extensively study of the Dyson-Schwinger equations for a fully dressed quark propagator in the "rainbow" approximation, a parametrized fully dressed quark propagator is proposed in this paper. The parametrized propagator describes a confining quark propagator in hadron since it is analytic everywhere in complex p2-plane and has no Lemmann representation. The validity of the new propagator is discussed by comparing its predictions on selfenergy functions Af(p2), Bf(p2) and effective mass Mf(p2) of quark with flavor f to their corresponding theoretical results produced by Dyson-Schwinger equations. Our comparison shows that the parametrized quark propagator is a good approximation to the fully dressed quark propagator given by the solutions of Dyson-Schwinger equations in the rainbow approximation and is convenient to use in any theoretical calculations.

  8. 电动汽车麦弗逊前悬架设计及参数优化%Design and Parametric Optimization of McPherson Front Suspension of Electric Vehicle

    Institute of Scientific and Technical Information of China (English)

    陆建辉; 周孔亢; 郭立娜; 侯永涛

    2012-01-01

    Based on the whole vehicle's design parameters and suspension design theories, the McPherson front suspension of an electric vehicle is designed. Based on UG/Motion and using the open interface of UG, a software system is developed to realize the parametric design of the McPherson suspension's kinematics simulation models, matching design of vehicle toe-in and camber and simulation analysis of the simulation models. The software system's correctness is verified by comparing the simulation results with ADAMS. By means of combining genetic algorithm with kinematics of multi-body system and taking the minimum variation of the front wheel alignment parameters as well as minimum lateral displacement of the tires as the optimal object, the McPherson suspension's design parameters are optimized. The validity of the optimum method is verified by comparing the simulation results of initial design and optimum design. The optimization results show that the coordinates of the McPherson suspension swing arm's front and rear points have effects on the changes curve of front wheel alignment parameters as well as lateral displacement of the tires to the run out of automotive wheels.%根据整车设计参数及悬架设计理论,设计某款电动汽车的麦弗逊前悬架.基于UG/Motion利用UG的开放接口开发相应的软件系统,实现麦弗逊前悬架运动学仿真模型的参数化设计、前轮外倾角与前束角的匹配设计和前悬架系统的运动学仿真分析;通过与ADAMS的仿真结果相对比,验证系统的正确性;将遗传优化算法与多体运动学分析方法相结合,以前轮定位参数的变化量最小和车轮侧向滑移量最小为优化目标对麦弗逊前悬架的设计参数进行优化,通过对比初始设计与优化设计的仿真结果,验证优化方法的有效性.优化分析显示,麦弗逊前悬架摆臂前后点坐标的变化,对前轮定位参数及车轮接地点滑移量随车轮跳动量的变化曲线都有影响.

  9. Safety evaluation for packaging (onsite) for cesium chloride capsules with type W overpacks

    Energy Technology Data Exchange (ETDEWEB)

    McCoy, J.C.

    1997-09-15

    This Safety Evaluation for Packaging (SEP) documents the evaluation of a new basket design and overpacked cesium chloride capsule payload for the Beneficial Uses Shipping System (BUSS) Cask in accordance with the onsite transportation requirements of the Hazardous Material Packaging and Shipping manual, WHC-CM-2-14. This design supports the one-time onsite shipment of 16 cesium chloride capsules with Type W overpacks from the 324 Building to the 224T Building at the Waste Encapsulation and Storage Facility (WESF). The SEP is valid for a one-time onsite shipment or until August 1, 1998, whichever occurs first.

  10. Relational Parametricity and Separation Logic

    DEFF Research Database (Denmark)

    Birkedal, Lars; Yang, Hongseok

    2008-01-01

    Separation logic is a recent extension of Hoare logic for reasoning about programs with references to shared mutable data structures. In this paper, we provide a new interpretation of the logic for a programming language with higher types. Our interpretation is based on Reynolds's relational...... parametricity, and it provides a formal connection between separation logic and data abstraction. Udgivelsesdato: 2008...

  11. A wireless capsule system with ASIC for monitoring the physiological signals of the human gastrointestinal tract.

    Science.gov (United States)

    Xu, Fei; Yan, Guozheng; Zhao, Kai; Lu, Li; Gao, Jinyang; Liu, Gang

    2014-12-01

    This paper presents the design of a wireless capsule system for monitoring the physiological signals of the human gastrointestinal (GI) tract. The primary components of the system include a wireless capsule, a portable data recorder, and a workstation. Temperature, pH, and pressure sensors; an RF transceiver; a controlling and processing application specific integrated circuit (ASIC); and batteries were applied in a wireless capsule. Decreasing capsule size, improving sensor precision, and reducing power needs were the primary challenges; these were resolved by employing micro sensors, optimized architecture, and an ASIC design that include power management, clock management, a programmable gain amplifier (PGA), an A/D converter (ADC), and a serial peripheral interface (SPI) communication unit. The ASIC has been fabricated in 0.18- μm CMOS technology with a die area of 5.0 mm × 5.0 mm. The wireless capsule integrating the ASIC controller measures Φ 11 mm × 26 mm. A data recorder and a workstation were developed, and 20 cases of human experiments were conducted in hospitals. Preprocessing in the workstation can significantly improve the quality of the data, and 76 original features were determined by mathematical statistics. Based on the 13 optimal features achieved in the evaluation of the features, the clustering algorithm can identify the patients who lack GI motility with a recognition rate reaching 83.3%.

  12. Scaling effects in spiral capsule robots.

    Science.gov (United States)

    Liang, Liang; Hu, Rong; Chen, Bai; Tang, Yong; Xu, Yan

    2017-04-01

    Spiral capsule robots can be applied to human gastrointestinal tracts and blood vessels. Because of significant variations in the sizes of the inner diameters of the intestines as well as blood vessels, this research has been unable to meet the requirements for medical applications. By applying the fluid dynamic equations, using the computational fluid dynamics method, to a robot axial length ranging from 10(-5) to 10(-2) m, the operational performance indicators (axial driving force, load torque, and maximum fluid pressure on the pipe wall) of the spiral capsule robot and the fluid turbulent intensity around the robot spiral surfaces was numerically calculated in a straight rigid pipe filled with fluid. The reasonableness and validity of the calculation method adopted in this study were verified by the consistency of the calculated values by the computational fluid dynamics method and the experimental values from a relevant literature. The results show that the greater the fluid turbulent intensity, the greater the impact of the fluid turbulence on the driving performance of the spiral capsule robot and the higher the energy consumption of the robot. For the same level of size of the robot, the axial driving force, the load torque, and the maximum fluid pressure on the pipe wall of the outer spiral robot were larger than those of the inner spiral robot. For different requirements of the operating environment, we can choose a certain kind of spiral capsule robot. This study provides a theoretical foundation for spiral capsule robots.

  13. Lubricin in human breast tissue expander capsules.

    Science.gov (United States)

    Cheriyan, Thomas; Guo, Lifei; Orgill, Dennis P; Padera, Robert F; Schmid, Thomas M; Spector, Myron

    2012-10-01

    Capsular contraction is the most common complication of breast reconstruction surgery. While presence of the contractile protein alpha smooth muscle actin (α-SMA) is considered among the causes of capsular contraction, the exact etiology and pathophysiology is not fully understood. The objective of this study was to investigate the possible role of lubricin in capsular formation and contraction by determining the presence and distribution of the lubricating protein lubricin in human breast tissue expander capsules. Related aims were to evaluate select histopathologic features of the capsules, and the percentage of cells expressing α-SMA, which reflects the myofibroblast phenotype. Capsules from tissue expanders were obtained from eight patients. Lubricin, at the tissue-implant interface, in the extracellular matrix, and in cells, and α-SMA-containing cells were evaluated immunohistochemically. The notable finding was that lubricin was identified in all tissue expander capsules: as a discrete layer at the tissue-implant interface, extracellular, and intracellular. There was a greater amount of lubricin in the extracellular matrix in the intimal-subintimal zone when compared with the tissue away from the implant. Varying degrees of synovial metaplasia were seen at the tissue-implant interface. α-SMA-containing cells were also seen in all but one patient. The findings might help us better understand factors involved in capsule formation.

  14. Surface and Volume Grid Generation in Parametric Form

    Science.gov (United States)

    Yu, Tzuyi; Soni, Bharat K.; Benjamin, Ted; Williams, Robert

    1996-01-01

    The algorithm for surface modeling and volume grid generation using parametric Non-Uniform Rational B-splines (NURBS) geometric representation are presented. The enhanced re-parameterization algorithm which can yield a desired physical distribution on the curve, surface, and volume is also presented. This approach bridges the gap between computer aided design surface/volume definition and surface/volume grid generation.

  15. DEVELOPING PARAMETRIC BUILDING MODELS – THE GANDIS USE CASE

    Directory of Open Access Journals (Sweden)

    W. Thaller

    2012-09-01

    Full Text Available In the course of a project related to green building design, we have created a group of eight parametric building models that can be manipulated interactively with respect to dimensions, number of floors, and a few other parameters. We report on the commonalities and differences between the models and the abstractions that we were able to identify.

  16. Unsteady Pressures on a Generic Capsule Shape

    Science.gov (United States)

    Burnside, Nathan; Ross, James C.

    2015-01-01

    While developing the aerodynamic database for the Orion spacecraft, the low-speed flight regime (transonic and below) proved to be the most difficult to predict and measure accurately. The flow over the capsule heat shield in descent flight was particularly troublesome for both computational and experimental efforts due to its unsteady nature and uncertainty about the boundary layer state. The data described here were acquired as part of a study to improve the understanding of the overall flow around a generic capsule. The unsteady pressure measurements acquired on a generic capsule shape are presented along with a discussion about the effects of various flight conditions and heat-shield surface roughness on the resulting pressure fluctuations.

  17. Intestinal preparation prior to capsule endoscopy administration

    Institute of Scientific and Technical Information of China (English)

    Vicente Pons Beltrán; Cristina Carretero; Bego(n)a Gonzalez-Suárez; I(n)aqui Fernández-Urien; Miguel Mu(n)oz Navas

    2008-01-01

    In order to have an adequate view of the whole small intestine during capsule endoscopy,the preparation recommended consists of a clear liquid diet and an overnight fast.However,visualization of the small bowel during video capsule endoscopy can be impaired by intestinal contents.To improve mucosal visualization,some authors have evaluated different regimens of preparation.There is no consensus about the necessity of intestinal preparation for capsule endoscopy and it should be interesting to develop adequate guidelines to improve its efficacy and tolerability.Moreover,the effect of preparation type (purgative) on intestinal transit time is not clear.Since a bowel preparation cannot definitively improve its visibility (and theoretically the yield of the test),it is not routinely recommended.

  18. Spectral measurements of asymmetrically irradiated capsule backlighters

    Science.gov (United States)

    Keiter, P. A.; Drake, R. P.

    2016-11-01

    Capsule backlighters provide a quasi-continuum x-ray spectrum over a wide range of photon energies [J. F. Hansen et al., Rev. Sci. Instrum. 79, 013504 (2008)]. Ideally one irradiates the capsule backlighter symmetrically, however, in complex experimental geometries, this is not always possible. In recent experiments we irradiated capsule backlighters asymmetrically and measured the x-ray spectrum from multiple directions. We will present time-integrated spectra over the photon energy range of 2-13 keV and time-resolved spectra over the photon energy range of 2-3 keV. We will compare the spectra from different lines of sight to determine if the laser asymmetry results in an angular dependence in the x-ray emission.

  19. Capsule endoscopy—A mechatronics perspective

    Science.gov (United States)

    Lin, Lin; Rasouli, Mahdi; Kencana, Andy Prima; Tan, Su Lim; Wong, Kai Juan; Ho, Khek Yu; Phee, Soo Jay

    2011-03-01

    The recent advances in integrated circuit technology, wireless communication, and sensor technology have opened the door for development of miniature medical devices that can be used for enhanced monitoring and treatment of medical conditions. Wireless capsule endoscopy is one of such medical devices that has gained significant attention during the past few years. It is envisaged that future wireless capsule endoscopies replace traditional endoscopy procedures by providing advanced functionalities such as active locomotion, body fluid/tissue sampling, and drug delivery. Development of energy-efficient miniaturized actuation mechanisms is a key step toward achieving this goal. Here, we review some of the actuators that could be integrated into future wireless capsules and discuss the existing challenges.

  20. Non-Parametric Inference in Astrophysics

    CERN Document Server

    Wasserman, L H; Nichol, R C; Genovese, C; Jang, W; Connolly, A J; Moore, A W; Schneider, J; Wasserman, Larry; Miller, Christopher J.; Nichol, Robert C.; Genovese, Chris; Jang, Woncheol; Connolly, Andrew J.; Moore, Andrew W.; Schneider, Jeff; group, the PICA

    2001-01-01

    We discuss non-parametric density estimation and regression for astrophysics problems. In particular, we show how to compute non-parametric confidence intervals for the location and size of peaks of a function. We illustrate these ideas with recent data on the Cosmic Microwave Background. We also briefly discuss non-parametric Bayesian inference.

  1. Development of Naphthalene PLIF for Visualizing Ablation Products From a Space Capsule Heat Shield

    Science.gov (United States)

    Combs, C. S.; Clemens, N. T.; Danehy, P. M.

    2014-01-01

    The Orion Multi-Purpose Crew Vehicle (MPCV) will use an ablative heat shield. To better design this heat shield and others that will undergo planetary entry, an improved understanding of the ablation process would be beneficial. Here, a technique developed at The University of Texas at Austin that uses planar laser-induced fluorescence (PLIF) of a low-temperature sublimating ablator (naphthalene) to enable visualization of the ablation products in a hypersonic flow is applied. Although high-temperature ablation is difficult and expensive to recreate in a laboratory environment, low-temperature sublimation creates a limited physics problem that can be used to explore ablation-product transport in a hypersonic flow-field. In the current work, a subscale capsule reentry vehicle model with a solid naphthalene heat shield has been tested in a Mach 5 wind tunnel. The PLIF technique provides images of the spatial distribution of sublimated naphthalene in the heat-shield boundary layer, separated shear layer, and backshell recirculation region. Visualizations of the capsule shear layer using both naphthalene PLIF and Schlieren imaging compared favorably. PLIF images have shown high concentrations of naphthalene in the capsule separated flow region, intermittent turbulent structures on the heat shield surface, and interesting details of the capsule shear layer structure. It was shown that, in general, the capsule shear layer appears to be more unsteady at lower angels of attack. The PLIF images demonstrated that during a wind tunnel run, as the model heated up, the rate of naphthalene ablation increased, since the PLIF signal increased steadily over the course of a run. Additionally, the shear layer became increasingly unsteady over the course of a wind tunnel run, likely because of increased surface roughness but also possibly because of the increased blowing. Regions with a relatively low concentration of naphthalene were also identified in the capsule backshell

  2. Hybrid-free Josephson Parametric Converter

    Science.gov (United States)

    Frattini, N. E.; Narla, A.; Sliwa, K. M.; Shankar, S.; Hatridge, M.; Devoret, M. H.

    A necessary component for any quantum computation architecture is the ability to perform efficient quantum operations. In the microwave regime of superconducting qubits, these quantum-limited operations can be realized with a non-degenerate Josephson junction based three-wave mixer, the Josephson Parametric Converter (JPC). Currently, the quantum signal of interest must pass through a lossy 180 degree hybrid to be presented as a differential drive to the JPC. This hybrid therefore places a limit on the quantum efficiency of the system and also increases the device footprint. We present a new design for the JPC eliminating the need for any external hybrid. We also show that this design has nominally identical performance to the conventional JPC. Work supported by ARO, AFOSR and YINQE.

  3. Video capsule endoscopy in inflammatory bowel disease

    Science.gov (United States)

    Collins, Paul D

    2016-01-01

    Video capsule endoscopy (VCE) has evolved to become an important tool for the non-invasive examination of the small bowel, which hitherto had been relatively inaccessible to direct visualisation. VCE has been shown to play a role in monitoring the activity of small bowel Crohn’s disease and can be used to assess the response to anti-inflammatory treatment in Crohn’s disease. For those patients with Crohn’s disease who have undergone an intestinal resection, VCE has been assessed as a tool to detect post-operative recurrence. VCE may also aid in the reclassification of patients with a diagnosis of Inflammatory Bowel Disease Unclassified to Crohn’s disease. The evolution of colon capsule endoscopy (CCE) has expanded the application of this technology further. The use of CCE to assess the activity of ulcerative colitis has been described. This advance in capsule technology has also fuelled interest in its potential role as a minimally invasive tool to assess the whole of GI tract opening the possibility of its use for the panenteric assessment of Crohn’s disease. VCE is a safe procedure. However, the risk of a retained capsule is higher in patients with suspected or confirmed Crohn’s disease compared with patients having VCE examination for other indications. A retained video capsule is rare after successful passage of a patency capsule which may be utilised to pre-screen patients undergoing VCE. This paper describes the use of VCE in the assessment of inflammatory bowel disease. PMID:27499830

  4. A quadratic-shaped-finger comb parametric resonator

    Science.gov (United States)

    Guo, Congzhong; Fedder, Gary K.

    2013-09-01

    A large-stroke (8 µm) parametric resonator excited by an in-plane ‘shaped-finger’ electrostatic comb drive is fabricated using a 15 µm thick silicon-on-insulator microelectromechanical systems (SOI-MEMS) process. A quadratic capacitance-engagement response is synthesized by engineering a custom-shaped comb finger profile. A folded-flexure suspension allows lateral motion while constraining rotational modes. The excitation of the nonlinear parametric resonance is realized by selecting an appropriate combination of the linear and cubic electrostatic stiffness coefficients through a specific varying-gap comb-finger design. The large-amplitude parametric resonance promotes high signal-to-noise ratio for potential use in sensitive chemical gravimetric sensors, strain gauges, and mode-matched gyroscope applications.

  5. Capsules with external navigation and triggered release.

    Science.gov (United States)

    Shchukin, Dmitry G; Shchukina, Elena

    2014-10-01

    Encapsulation is an important technology for pharmaceutical industry, food production, et cetera. Its current level of development requires capsule functionalization. One of the interesting ideas to provide new functionality to the microcapsule and nanocapsule is layer-by-layer deposition of functional species. This technique provides step-by-step adsorption of various species (polyelectrolytes, nanoparticles, proteins) when the layer growth is controlled by electrostatic, hydrogen bonding, hydrophobic forces and forming multilayer shells with nanometer precision. This review article introduces recent achievements of layer-by-layer technique attaining external navigation ability and release properties the capsule shell.

  6. Extraction Process for Essential Oil of Acorus tatarinowii in Gutianquan Capsule by Orthogonal Design%正交法优选固天泉胶囊中石菖蒲挥发油提取工艺

    Institute of Scientific and Technical Information of China (English)

    汤道权; 金磊; 殷放宙; 张弦

    2001-01-01

    Objective:To study the extraction process for essential oil Acorus tatarinowii in Gutianquan capsule.Methods:To study the extraction process for essential oil of Acorus tatarinowii by steam distillation.Results:Volume of essential oil was not relevant to water volume,immerse time but was relevent to extraction time.Conclusion:The best extraction process is to extract herb with 8 times of water,immers for 1 hour,extrat for 6 hours.%目的:优选固天泉胶囊中石菖蒲挥发油的提取工艺。方法:采用水蒸气蒸馏法对石菖蒲挥发油的提取工艺进行正交优选。结果:挥发油的提取得率与加水量、浸泡时间关系不大,而与提取时间的长短有一定的关系。结论:加水量8倍,浸泡时间1 h,提取时间6 h为最佳工艺。

  7. 基于NX8.0盘形凸轮轮廓曲线的参数化设计及运动仿真%Parametric Design and Motion Simulation of Disc Cam Profile Curve Based on NX8.0

    Institute of Scientific and Technical Information of China (English)

    张恩光; 王丽; 黄冠元; 惠帅

    2014-01-01

    This paper presents a parametric design method of the cam profile curve with“law curve”function of NX8.0,analyzes the continuity of the cam profile curve and verifies the correctness of the design through the cam motion simulation. Through the analysis of the displacement and velocity motion laws of the fol ower,the parametric drive of the cam design is verified. The result shows that the CAD and CAE module of NX8.0 can is used for the parametric design and motion analysis of the cam profile curve to ful y guaran-tee the design accuracy and greatly improve the editability and reusability of the model.%介绍了利用NX8.0的“规律曲线”功能对凸轮轮廓曲线进行参数化设计的方法,分析了凸轮轮廓曲线的连续性,通过对凸轮的运动仿真验证了设计结果的正确性,分析了从动件的位移和速度的运动规律,验证了凸轮设计的参数化驱动,结果表明使用NX8.0的CAD和CAE模块对凸轮轮廓曲线进行参数化设计和运动分析能够充分保证设计精度,大大提高了模型可编辑性与重用性。

  8. Capsule endoscopy: Current status in obscure gastrointestinal bleeding

    Institute of Scientific and Technical Information of China (English)

    R Gupta; Nageshwar Duvvuru Reddy

    2007-01-01

    Capsule endoscopy (CE) is a safe, non invasive diagnostic modality for the evaluation of small bowel lesions. Obscure gastrointestinal bleeding (OGIB) is one of the most important indications of capsule endoscopy.Capsule endoscopy has a very high diagnostic yield especially if the bleeding is ongoing. This technique appears to be superior to other techniques for the detection of suspected lesions and the source of bleeding. Capsule endoscopy has been shown to change the outcome in patients with obscure gastrointestinal (GI)bleed.

  9. Altered multiaxial mechanical properties of the porcine anterior lens capsule cultured in high glucose.

    Science.gov (United States)

    Pedrigi, R M; Staff, E; David, G; Glenn, S; Humphrey, J D

    2007-02-01

    Hyperglycemia can alter the mechanical properties of tissues through the formation of advanced glycation endproducts in matrix proteins that have long half-lives. We used a custom experimental system and subdomain finite element method to quantify alterations in the regional multiaxial mechanical properties of porcine lens capsules that were cultured for 8 or 14 weeks in high glucose versus control media. Findings revealed that high glucose significantly stiffened the capsules in both the circumferential and the meridional directions, but it did not affect the known regional variations in anisotropy. Such information could be important in the design of both improved clinical procedures and intraocular implants for diabetic patients.

  10. Parametric Dwarf Spheroidal Tidal Interaction

    CERN Document Server

    Fleck, J J; Fleck, Jean-Julien; Kuhn, Jeff R.

    2003-01-01

    The time dependent tidal interaction of the Local Group Dwarf Spheroidal (dS) Galaxies with the Milky Way (MW) can fundamentally affect their dynamical properties. The model developed here extends earlier numerical descriptions of dS-MW tidal interactions. We explore the dynamical evolution of dS systems in circular or elliptical MW orbits in the framework of a parametric oscillator. An analytic model is developed and compared with more general numerical solutions and N-body simulation experiments.

  11. Synergistic action on hypnosia: Yinao capsules with pentobarbital sodium of threshold and sub-threshold dosages

    Institute of Scientific and Technical Information of China (English)

    Guilan Zhang; Mingsan Miao; Jingjing Shi; Yalei Yang

    2007-01-01

    BACKGROUND: Sedative and hypnotic drugs could cure insomnia in a dependent manner, and traditional Chinese medicine has some superiority in treating insomnia.OBJECTIVE: To observe the synergistic action of Yinao capsules with pentobarbital sodium in threshold and sub-threshold dosages in hypnosia and sedation.DESIGN: A completely randomized grouping design and control experiment.SETTING: Pharmacological laboratory, College of Pharmacy, Henan College of Traditional Chinese Medicine.MATERIALS: Totally 200 grade Ⅱ Kunming mice of 18 - 21 g, either male or female, were used. Yinao capsules, main ingredients of which were turtleback glue, thinleaf milkwort root, Chinese magnoliavine fruit,mythic fungus, tangshen, ginseng and grassleaf sweetflag rhizome, were offered by Chinese-American Huayi Pharmacy, Co.,Ltd. (ratified number: 040901); Kangnaoshuai capsules, main ingredients of which were prepared rehmannia root, tuber fleeceflower root, ginseng, membranous milkvetch root, thinleaf milkwort root, Fushen, grassleaf sweetflag rhizome, spine date seed, lecithin, barbary wolfberry fruit, pueraria root,vitamin E, etc., were produced by Shijiazhuang Siyao, Co.,Ltd. (ratified number: 040964); Pentobarbital sodium was produced by China Medicine (Group) Shanghai Chemical Reagent, Co,.Ltd. (Ratified number:030816). ZZ-6 mice spontaneous activity apparatus was produced by Chengdu Taimeng Science and Technology, Co.,Ltd.METHODS: The experiment was carried out in the Animal Experimental Center, Henan College of spontaneous activity of mice: Fifty mice were randomly divided into five groups with 10 mice in each group:Mice in the large, middle and small dosages of Yinao capsules groups were intragastrically infused with Yinao capsules suspension (1.36, 0.68, 0.34 g/kg); Those in the Kangnaoshuai capsules group were infused with Kangnaoshuai suspension (1.12 g/kg); Those in the control group were given physiologic saline of the same volume. The mice were administrated once a day for

  12. 21 CFR 872.3110 - Dental amalgam capsule.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Dental amalgam capsule. 872.3110 Section 872.3110...) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices § 872.3110 Dental amalgam capsule. (a) Identification. A dental amalgam capsule is a container device in which silver alloy is intended to be mixed with...

  13. Prompt Beta Spectroscopy as a Diagnostic for Mix in Ignited NIF Capsules

    CERN Document Server

    Hayes, A C; Solem, J C; Bradley, P A; Rundberg, R S

    2004-01-01

    The National Ignition Facility (NIF) technology is designed to drive deuterium-tritium (DT) internal confinement fusion (ICF) targets to ignition using indirect radiation from laser beam energy captured in a hohlraum. Hydrodynamical instabilities at interfaces in the ICF capsule leading to mix between the DT fue l and the ablator shell material are of fundamental physical interest and can affect the performance characteristics of the capsule. In this Letter we describe new radiochemical diagnostics for mix processes in ICF capsules with plastic or Be (0.9%Cu) ablator shells. Reactions of high-energy tritons with shell material produce high-energy $\\beta$-emitters. We show that mix between the DT fuel and the shell material enhances high-energy prompt beta emission from these reactions by more than an order of magnitude over that expected in the absence of mix.

  14. Electrohydrodynamic deformation of capsules in electric field

    Science.gov (United States)

    Das, Sudip; Thaokar, Rochish

    2016-11-01

    Micron size capsules are abundant in natural, technological and biological processes but they still require extensive investigation for better understanding of their mechanical behavior. A spherical capusle containing a Newtonian fluid bounded by a viscoelastic membrane and immersed in another Newtonian fluid, and subject to electric field is considered. Discontinuity of electrical properties such as conductivity and permittivity leads to a net Maxwell stress at the capsule interface. In response the capsule undergoes elastic deformation, leading to strain fields and elastic stresses that can balance the applied forces. We investigate this problem with fully resolved hydrodynamics in the Stokes flow limit and electrostatics using the capacitance model. Effect of AC, DC and pulsed DC fields is investigated. Our results show that membrane electrical properties have a huge impact on the equilibrium deformation as well as on the break up of capsules. Our results match with the literature results in the limit of high conductance of the membrane. Analytical theory is employed using spherical harmonics and numerical investigations are conducted using the Boundary integral method.

  15. Student Mobility. Information Capsule. Volume 0608

    Science.gov (United States)

    Blazer, Christie

    2007-01-01

    Mobility, rather than stability, has become the norm for students in schools across the United States. The student mobility rate is now higher in the United States than in any other industrialized country. This Information Capsule discusses the reasons for student mobility and the characteristics of highly mobile students and families. Research…

  16. Bioequivalence of two lansoprazole delayed release capsules 30 mg in healthy male volunteers under fasting, fed and fasting-applesauce conditions: a partial replicate crossover study design to estimate the pharmacokinetics of highly variable drugs.

    Science.gov (United States)

    Thota, S; Khan, S M; Tippabhotla, S K; Battula, R; Gadiko, C; Vobalaboina, V

    2013-11-01

    An open-label, 2-treatment, 3-sequence, 3-period, single-dose, partial replicate crossover studies under fasting (n=48), fed (n=60) and fasting-applesauce (n=48) (sprinkled on one table spoonful of applesauce) modalities were conducted in healthy adult male volunteers to evaluate bioequivalence between 2 formulations of lansoprazole delayed release capsules 30 mg. In all the 3 studies, as per randomization, either test or reference formulations were administered in a crossover manner with a required washout period of at least 7 days. Blood samples were collected adequately (0-24 h) to determine lansoprazole plasma concentrations using a validated LC-MS/MS analytical method. To characterize the pharmacokinetic parameters (Cmax, AUC0-t, AUC0-∞, Tmax, Kel and T1/2) of lansoprazole, non-compartmental analysis and ANOVA was applied on ln-transformed values. The bioequivalence was tested based on within-subject variability of the reference formulation. In fasting and fed studies (within-subject variability>30%) bioequivalence was evaluated with scaled average bioequivalence, hence for the pharmacokinetic parameters Cmax, AUC0-t and AUC0-∞, the 95% upper confidence bound for (μT-μR)2-θσ2 WR was ≤0, and the point estimates (test-to-reference ratio) were within the regulatory acceptance limit 80.00-125.00%. In fasting-applesauce study (within-subject variability<30%) bioequivalence was evaluated with average bioequivalence, the 90% CI of ln-transformed data of Cmax, AUC0-t and AUC0-∞ were within the regulatory acceptance limit 80.00-125.00%. Based on these aforesaid statistical inferences, it was concluded that the test formulation is bioequivalent to reference formulation.

  17. [Post-marketing clinical study of traditional Chinese medicine--lessons learned from comprehensive evaluation of Fufang Zaoren capsule].

    Science.gov (United States)

    Qing, Shan; Gao, Lin; Zhang, Li; Jia, Jian-Ping; Liu, Xin-Min; Ji, Shao-Liang; Yang, Xiao-Hui

    2013-11-01

    By comprehensive review and analysis of post-marketing clinical research on the efficacy and safety,we concluded that Fufang Zaoren capsule has certain therapeutic effects for insomnia, although current clinical research design needs improving. The post-marketing clinical studies also showed that it causes several adverse reactions at the recommended doses, such as chills, fever, dizziness, nausea, shortness of breath, chest tightness and palpitations, whereas high doses of Fufang Zaoren capsule can cause delayed extrapyramidal symptoms. Health Canada government website also prompted the L-tetrahydropalmatine in Fufang Zaoren capsule caused liver damage in pregnant women. The authors summarized the risk points, factors and risk control in the clinical use of Fufang Zaoren capsule and also present their perspective on the research status, existing problems and corresponding countermeasures in the post-marketing clinical re-evaluation of traditional Chinese medicine.

  18. Tri-Center Analysis: Determining Measures of Trichotomous Central Tendency for the Parametric Analysis of Tri-Squared Test Results

    Science.gov (United States)

    Osler, James Edward

    2014-01-01

    This monograph provides an epistemological rational for the design of a novel post hoc statistical measure called "Tri-Center Analysis". This new statistic is designed to analyze the post hoc outcomes of the Tri-Squared Test. In Tri-Center Analysis trichotomous parametric inferential parametric statistical measures are calculated from…

  19. HANARO instrumented capsule development for supporting a study on the irradiation damage of stainless steels for nuclear applications

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Y. H.; Cho, M. S.; Sohn, J. M.; Kim, H. R.; Lee, B. C.; Kim, K. H

    2000-10-01

    As a part of the program for the maximum utilization of HANARO by MOST, Korea, an instrumented capsule (00M-01U) was designed and fabricated for supporting a study on the irradiation damage of stainless steels for nuclear applications. The basic structure of the capsule for the irradiation of Stainless steels was based on that of the 99M-01K capsule irradiated successfully in HANARO. To satisfy the user requirements such as irradiation temperature and neutron fluence, the optimal arrangement of test specimens was done in the axial and circumferential direction. The temperature distribution and thermal stress of a capsule with multi-holes were obtained by a finite element analysis code, ANSYS. From these analyzed data, this capsule was found to be compatible with HANARO design requirement. Various types of specimens such as small tensile, Charpy, TEM and EPMA specimens were inserted in the capsule. The specimens will be irradiated in the IR2 test hole of HANARO at 288, 300 and 350 deg C up to a fast neutron fluence of 1.0x10{sup 20}(n/cm{sup 2})(E>1.0MeV)

  20. Reinforcement Toolbox, a Parametric Reinforcement Modelling Tool for Curved Surface Structures

    NARCIS (Netherlands)

    Lauppe, J.; Rolvink, A.; Coenders, J.L.

    2013-01-01

    This paper presents a computational strategy and parametric modelling toolbox which aim at enhancing the design- and production process of reinforcement in freeform curved surface structures. The computational strategy encompasses the necessary steps of raising an architectural curved surface model

  1. Digital spectral analysis parametric, non-parametric and advanced methods

    CERN Document Server

    Castanié, Francis

    2013-01-01

    Digital Spectral Analysis provides a single source that offers complete coverage of the spectral analysis domain. This self-contained work includes details on advanced topics that are usually presented in scattered sources throughout the literature.The theoretical principles necessary for the understanding of spectral analysis are discussed in the first four chapters: fundamentals, digital signal processing, estimation in spectral analysis, and time-series models.An entire chapter is devoted to the non-parametric methods most widely used in industry.High resolution methods a

  2. Symptomatic Patency Capsule Retention in Suspected Crohn's Disease

    DEFF Research Database (Denmark)

    Rasmussen, Bjørn; Nathan, Torben; Jensen, Michael Dam

    2016-01-01

    The main limitation of capsule endoscopy is the risk of capsule retention. In patients with suspected Crohn's disease, however, this complication is rare, and if a small bowel stenosis is not reliably excluded, small bowel patency can be confirmed with the Pillcam patency capsule. We present two...... patients examined for suspected Crohn's disease who experienced significant symptoms from a retained patency capsule. Both patients had Crohn's disease located in the terminal ileum. In one patient, the patency capsule caused abdominal pain and vomiting and was visualized at magnetic resonance enterography...

  3. New algorithms for evaluating parametric surface

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Through generalization of mathematical model of surface lofting program in the CONSURF system, the definitions for two generalized Ball surfaces and their recursive algorithms are given. Furthermore, the conversion al gorithms from Bézier surface to these two generalized Ball surfaces are presented. On the basis of these algorithms, two more efficient algorithms for evaluating parametric surfaces are also derived. One uses generalized Ball forms directly for evaluating surface, and the other converts the given Bézier surface to a generalized Ball surface firstly, and then evalu ates the surface. Both theoretical analysis and example computations show that the two new algorithms are more efficient than the de Casteljau algorithm. Especially when Wang-Ball surface is used, the time complexity is reduced from cubic to quadratic of the degree of the surface. If these algorithms are applied to displaying, interactive rendering, designing, intersection-finding, offsetting and approximating for surfaces, considerable economic results can be achieved.

  4. Normal dispersion femtosecond fiber optical parametric oscillator.

    Science.gov (United States)

    Nguyen, T N; Kieu, K; Maslov, A V; Miyawaki, M; Peyghambarian, N

    2013-09-15

    We propose and demonstrate a synchronously pumped fiber optical parametric oscillator (FOPO) operating in the normal dispersion regime. The FOPO generates chirped pulses at the output, allowing significant pulse energy scaling potential without pulse breaking. The output average power of the FOPO at 1600 nm was ∼60  mW (corresponding to 1.45 nJ pulse energy and ∼55% slope power conversion efficiency). The output pulses directly from the FOPO were highly chirped (∼3  ps duration), and they could be compressed outside of the cavity to 180 fs by using a standard optical fiber compressor. Detailed numerical simulation was also performed to understand the pulse evolution dynamics around the laser cavity. We believe that the proposed design concept is useful for scaling up the pulse energy in the FOPO using different pumping wavelengths.

  5. Zero- vs. one-dimensional, parametric vs. non-parametric, and confidence interval vs. hypothesis testing procedures in one-dimensional biomechanical trajectory analysis.

    Science.gov (United States)

    Pataky, Todd C; Vanrenterghem, Jos; Robinson, Mark A

    2015-05-01

    Biomechanical processes are often manifested as one-dimensional (1D) trajectories. It has been shown that 1D confidence intervals (CIs) are biased when based on 0D statistical procedures, and the non-parametric 1D bootstrap CI has emerged in the Biomechanics literature as a viable solution. The primary purpose of this paper was to clarify that, for 1D biomechanics datasets, the distinction between 0D and 1D methods is much more important than the distinction between parametric and non-parametric procedures. A secondary purpose was to demonstrate that a parametric equivalent to the 1D bootstrap exists in the form of a random field theory (RFT) correction for multiple comparisons. To emphasize these points we analyzed six datasets consisting of force and kinematic trajectories in one-sample, paired, two-sample and regression designs. Results showed, first, that the 1D bootstrap and other 1D non-parametric CIs were qualitatively identical to RFT CIs, and all were very different from 0D CIs. Second, 1D parametric and 1D non-parametric hypothesis testing results were qualitatively identical for all six datasets. Last, we highlight the limitations of 1D CIs by demonstrating that they are complex, design-dependent, and thus non-generalizable. These results suggest that (i) analyses of 1D data based on 0D models of randomness are generally biased unless one explicitly identifies 0D variables before the experiment, and (ii) parametric and non-parametric 1D hypothesis testing provide an unambiguous framework for analysis when one׳s hypothesis explicitly or implicitly pertains to whole 1D trajectories.

  6. Optical parametric amplification and oscillation assisted by low-frequency stimulated emission

    CERN Document Server

    Longhi, Stefano

    2016-01-01

    Optical parametric amplification/oscillation provide a powerful tool for coherent light generation in spectral regions inaccessible to lasers. Parametric gain is based on a frequency {\\it down-conversion} process, and thus it can not be realized for signal waves at a frequency $\\omega_3$ {\\it higher} than the frequency of the pump wave $\\omega_1$. In this work we suggest a route toward the realization of {\\it up-conversion} optical parametric amplification and oscillation, i.e. amplification of the signal wave by a coherent pump wave of lower frequency, assisted by stimulated emission of the auxiliary idler wave. When the signal field is resonated in an optical cavity, parametric oscillation is obtained. Design parameters for the observation of up-conversion optical parametric oscillation at $\\lambda_3=465$ nm are given for a periodically-poled lithium-niobate (PPLN) crystal doped with Nd$^{3+}$ ions.

  7. A portable wireless power transmission system for video capsule endoscopes.

    Science.gov (United States)

    Shi, Yu; Yan, Guozheng; Zhu, Bingquan; Liu, Gang

    2015-01-01

    Wireless power transmission (WPT) technology can solve the energy shortage problem of the video capsule endoscope (VCE) powered by button batteries, but the fixed platform limited its clinical application. This paper presents a portable WPT system for VCE. Besides portability, power transfer efficiency and stability are considered as the main indexes of optimization design of the system, which consists of the transmitting coil structure, portable control box, operating frequency, magnetic core and winding of receiving coil. Upon the above principles, the correlation parameters are measured, compared and chosen. Finally, through experiments on the platform, the methods are tested and evaluated. In the gastrointestinal tract of small pig, the VCE is supplied with sufficient energy by the WPT system, and the energy conversion efficiency is 2.8%. The video obtained is clear with a resolution of 320×240 and a frame rate of 30 frames per second. The experiments verify the feasibility of design scheme, and further improvement direction is discussed.

  8. AN ELECTROMAGNETIC PNEUMO CAPSULE SYSTEM FOR CONVEYING MINERALS AND MINE WASTES

    Energy Technology Data Exchange (ETDEWEB)

    Henry Liu; Charles W. Lenau

    2005-03-01

    The purpose of this project is to investigate the technical and economic feasibility of using a new and advanced pneumatic capsule pipeline (PCP) system for transporting minerals and mine wastes. The new system is different from conventional PCPs in two main respects: (1) it uses linear induction motors (LIMs) instead of blowers (fans) at the inlet of the pipeline to drive (pump) the capsules and the air through the pipeline; and (2) the capsules in the PCP have steel wheels running on steel rails as opposed to capsules in conventional systems, which use wheels with rubber tires running inside a pipe without rail. The advantage of using LIM pump instead of blower is that the former is non-intrusive and hence does not block the passage of capsules, enabling the system to run continuously without having to make the capsules bypass the pump. This not only simplifies the system but also enables the system to achieve much larger cargo throughput than that of PCPs using blowers, and use of LIMs as booster pumps which enables the system to have any length or to be used for transporting cargoes over practically any distance, say even one thousand kilometers or miles. An advantage of using steel wheels rolling on steel rails instead of using rubber tires rolling inside a pipeline is that the rolling friction coefficient and hence the use of energy is greatly reduced from that of conventional PCP systems. Moreover, rails enable easy control of capsule motion, such as switching capsules to a branch line by using railroad switching equipment. The advanced PCP system studied under this project uses rectangular conduits instead of circular pipe, having cross-sectional areas of 1 m by 1 m approximately. The system can be used for various transportation distances, and it can transport up to 50 million tonnes (metric tons) of cargo annually--the throughput of the largest mines in the world. Both an aboveground and an underground system were investigated and compared. The technical

  9. Parametric resonance in ideal magnetohydrodynamics

    Science.gov (United States)

    Zaqarashvili

    2000-08-01

    We show that an external nonelectromagnetic periodic inhomogeneous force sets up a parametric resonance in an ideal magnetohydrodynamics. Alfven waves with certain wavelengths grow exponentially in amplitude. Nonlinear interaction between the resonant harmonics produces the long-term modulation of amplitudes. The mechanism of the energy transformation from an external nonelectromagnetic force to magnetic oscillations of the system presented here can be used in understanding the physical background of the gravitational action on the magnetized medium. Future application of this theory to several astrophysical problems is briefly discussed.

  10. Parametric nanomechanical amplification at very high frequency.

    Science.gov (United States)

    Karabalin, R B; Feng, X L; Roukes, M L

    2009-09-01

    Parametric resonance and amplification are important in both fundamental physics and technological applications. Here we report very high frequency (VHF) parametric resonators and mechanical-domain amplifiers based on nanoelectromechanical systems (NEMS). Compound mechanical nanostructures patterned by multilayer, top-down nanofabrication are read out by a novel scheme that parametrically modulates longitudinal stress in doubly clamped beam NEMS resonators. Parametric pumping and signal amplification are demonstrated for VHF resonators up to approximately 130 MHz and provide useful enhancement of both resonance signal amplitude and quality factor. We find that Joule heating and reduced thermal conductance in these nanostructures ultimately impose an upper limit to device performance. We develop a theoretical model to account for both the parametric response and nonequilibrium thermal transport in these composite nanostructures. The results closely conform to our experimental observations, elucidate the frequency and threshold-voltage scaling in parametric VHF NEMS resonators and sensors, and establish the ultimate sensitivity limits of this approach.

  11. Parametric programming of CNC machine tools

    Directory of Open Access Journals (Sweden)

    Gołębski Rafał

    2017-01-01

    Full Text Available The article presents the possibilities of parametric programming of CNC machine tools for the SINUMERIK 840D sl control system. The kinds and types of the definition of variables for the control system under discussion described. On the example of the longitudinal cutting cycle, parametric programming possibilities are shown. The program’s code and its implementation in the control system is described in detail. The principle of parametric programming in a high-level language is also explained.

  12. Parametric resonance in neutrino oscillations in matter

    Indian Academy of Sciences (India)

    E Kh Akhmedov

    2000-01-01

    Neutrino oscillations in matter can exhibit a specific resonance enhancement - parametric resonance, which is different from the MSW resonance. Oscillations of atmospheric and solar neutrinos inside the earth can undergo parametric enhancement when neutrino trajectories cross the core of the earth. In this paper we review the parametric resonance of neutrino oscillations in matter. In particular, physical interpretation of the effect and the prospects of its experimental observation in oscillations of solar and atmospheric neutrinos in the earth are discussed.

  13. Effectiveness of Qiangjijianli capsule on experimental autoimmune myasthenia gravis

    Institute of Scientific and Technical Information of China (English)

    Shunmin Li; Bo Fu; Yuyan Li; DongYang; Shudong Yang

    2006-01-01

    BACKGROUND: Experimental autoimmune myasthenia gravis(EAMG) and anti-AchR antibody of human myasthenia gravis are the same immune globulin.This antibody restricts the activity of nicotinic acetylcholine receptor and the amount of receptor binding sites is decreased,so myasthenia gravis occurs.OBJECTIVE: To observe the therapeutic effect and mechanism of action of Qiangjijianli capsule on EAMG rats.DESIGN:A randomized controlled animal experiment.SETTING: Experimental Animal Center of Guangzhou University of Traditional Chinese Medicine.MATERIALS: Acetylcholine receptors(AchR)were extracted from electric skate's electric organ which lives in the sea near Guangzhou.It had high biological activity and the protein content was 1.63 g/L.Qiangjijianli capsule (Astragalus mongholicus,Codonopsis pilosula,Atractylodes macrocephala,Angelica sinensis,Bupleurum chinense,Cairo morningglory root or leaf,Glycyrrhixa uralensis,etc.0.5 g crude drug per capsule) was bought from the Manufacturing Laboratory of Guangzhou University of Traditional Chinese Medicine with the Batch No.89-11-1.METHODS:This experiment was carried out in the Experimental Animal Center of Guangzhou University of Traditional Chinese Medicine from May to August 1990.①Adult female SD rats were immunized with AchR.The animals' movement condition was observed and recorded everyday. Ten rats were chosen as normal control group.and they were not given any treatment and raised normally.After modeled,20 successful rats were randomly assigned into 2 groups:treatmental group and model group. 2 mL Qiangjijianli capsule suspension(1 g)was intragastrically administrated into each rat of treatmental group for 30 days; The same amount of clean water was intragastrically administrated into the rats of model group for 30 days.(2)Serum AchR antibody was measured with ABC-ELISA method. After administration,the rats were sacrificed.The complete diaphragmatic muscle was extracted for in vitro receptor binding test

  14. Angle-Resolved Spectroscopy of Parametric Fluorescence

    CERN Document Server

    Hsu, Feng-kuo

    2013-01-01

    The parametric fluorescence from a nonlinear crystal forms a conical radiation pattern. We measure the angular and spectral distributions of parametric fluorescence in a beta-barium borate crystal pumped by a 405-nm diode laser employing angle-resolved imaging spectroscopy. The experimental angle-resolved spectra and the generation efficiency of parametric down conversion are compared with a plane-wave theoretical analysis. The parametric fluorescence is used as a broadband light source for the calibration of the instrument spectral response function in the wavelength range from 450 to 1000 nm.

  15. Triminimal parametrization of quark mixing matrix

    Science.gov (United States)

    He, Xiao-Gang; Li, Shi-Wen; Ma, Bo-Qiang

    2008-12-01

    Starting from a new zeroth order basis for quark mixing (CKM) matrix based on the quark-lepton complementarity and the tribimaximal pattern of lepton mixing, we derive a triminimal parametrization of a CKM matrix with three small angles and a CP-violating phase as its parameters. This new triminimal parametrization has the merits of fast convergence and simplicity in application. With the quark-lepton complementary relations, we derive relations between the two unified triminimal parametrizations for quark mixing obtained in this work and for lepton mixing obtained by Pakvasa-Rodejohann-Weiler. Parametrization deviating from quark-lepton complementarity is also discussed.

  16. An improved YEF-DCT based compression algorithm for video capsule endoscopy.

    Science.gov (United States)

    Mostafa, Atahar; Khan, Tareq; Wahid, Khan

    2014-01-01

    Video capsule endoscopy is a non-invasive technique to receive images of intestine for medical diagnostics. The main design challenges of endoscopy capsule are accruing and transmitting acceptable quality images by utilizing as less hardware and battery power as possible. In order to save wireless transmission power and bandwidth, an efficient image compression algorithm needs to be implemented inside the endoscopy electronic capsule. In this paper, an integer discrete-cosine-transform (DCT) based algorithm is presented that works on a low-complexity color-space specially designed for wireless capsule endoscopy application. First of all, thousands of human endoscopic images and video frames have been analyzed to identify special intestinal features present in those frames. Then a color space, referred as YEF, is used. The YEF converter is lossless and takes only a few adders and shift operation to implement. A low-cost quantization scheme with variable chroma sub-sampling options is also implemented to achieve higher compression. Comparing with the existing works, the proposed transform coding based compressor performs strongly with an average compression ratio of 85% and a high image quality index, peak-signal-to-noise ratio (PSNR) of 52 dB.

  17. Out-pile test of the capsule with cone shape bottom structures

    Energy Technology Data Exchange (ETDEWEB)

    Choi, M. H.; Kang, Y. H.; Cho, M. S.; Choo, K. N.; Kim, B. G.; Son, J. M.; Park, S. J.; Shin, Y. T.; Oh, J. M

    2004-01-01

    The design modification of bottom guide structures for the instrumented capsule which is used for the irradiation test in the research reactor, HANARO is done because of the cutting trouble of the bottom guide arm's pin. The previous structure of the 3-pin arm shape is changed into one body of the cone shape. The specimens of the bottom end cap ring with three different sizes ({phi}68mm, {phi}70mm, {phi}72mm) are designed and manufactured. The out-pile test for the capsule with previous 3-pin arm and new three bottom structures of the cone shape is performed using the one-channel flow test facilities. In order to estimate the compatibility with HANARO, the structural stability and integrity of the capsule, the out-pile test such as a loading/unloading test, a pressure drop test, a thermal performance test, a displacement measurement due to a vibration and an endurance test etc. is conducted, and the outer diameter of the bottom end cap ring to meet the HANARO requirements is selected. From out-pile test results the capsule with cone shape bottom structures is evaluated as to have the structural stability and the benefit from the fluid's flow respect. Also the size satisfied various requirements among three kinds of bottom end cap rings is 70mm in diameter. It is expected that the new bottom structures of the cone shape with 70mm in diameter will be applicable to all material and special capsules which will be designed and manufactured for the purpose of irradiation tests in the future.

  18. 基于电子、气动技术和CANopen总线的膜盒柔性自动化装配系统设计%Design of Flexible and Automatic Assembly of Capsule Based on CANopen Bus, Pneumatic and Electric Technology

    Institute of Scientific and Technical Information of China (English)

    陈水金

    2012-01-01

    基于气动技术、电子技术及数字控制技术的柔性装配是精密仪器仪表制造及装配中的核心技术.针对流水线式变送器膜盒的自动化装配工艺,提出切实可行的柔性自动装配方案,设计并优化各模块气动机械手和电、气结合机械手,并根据装配系统工艺要求设计了可靠的电、气结合的柔性装配系统;基于软PLC和CANopen总线协议,设计I/0从站并实现了高精度自动化装配分布式现场总线控制系统,为精密仪器仪表柔性装配应用提供了参考.%The flexible assembly based on pneumatic, electric and digital control technologies is one of key approaches for the fabrication and assembly of precision instruments and apparatus. Aiming at the pipeline automatic assembly technology of transmitter capsule in instruments, a feasible approach for flexible and automatic assembly was presented. The pneumatic and electric manipulators of each module were designed and optimized. A reliable flexible assembly system was designed according to the process requirement of practical assembly system. The I/O slave stations and high precision distributed field bus control system of automatic assembly were designed based on soft PLC and CANopen bus protocol. This work provides an important reference for the design of flexible assembly application in instrumental industry.

  19. A Parametric Modelling Method for Dexterous Finger Reachable Workspaces

    Directory of Open Access Journals (Sweden)

    Wenzhen Yang

    2016-03-01

    Full Text Available The well-known algorithms, such as the graphic method, analytical method or numerical method, have some defects when modelling the dexterous finger workspace, which is a significant kinematical feature of dexterous hands and valuable for grasp planning, motion control and mechanical design. A novel modelling method with convenient and parametric performances is introduced to generate the dexterous-finger reachable workspace. This method constructs the geometric topology of the dexterous-finger reachable workspace, and uses a joint feature recognition algorithm to extract the kinematical parameters of the dexterous finger. Compared with graphic, analytical and numerical methods, this parametric modelling method can automatically and conveniently construct a more vivid workspace’ forms and contours of the dexterous finger. The main contribution of this paper is that a workspace-modelling tool with high interactive efficiency is developed for designers to precisely visualize the dexterous-finger reachable workspace, which is valuable for analysing the flexibility of the dexterous finger.

  20. Resonant Dampers for Parametric Instabilities in Gravitational Wave Detectors

    CERN Document Server

    Gras, Slawek; Barsotti, Lisa; Evans, Matthew

    2015-01-01

    Advanced gravitational wave interferometric detectors will operate at their design sensitivity with nearly 1MW of laser power stored in the arm cavities. Such large power may lead to the uncontrolled growth of acoustic modes in the test masses due to the transfer of optical energy to the mechanical modes of the arm cavity mirrors. These parametric instabilities have the potential of significantly compromising the detector performance and control. Here we present the design of "acoustic mode dampers" that use the piezoelectric effect to reduce the coupling of optical to mechanical energy. Experimental measurements carried on an Advanced LIGO-like test mass shown a 10-fold reduction in the amplitude of several mechanical modes, thus suggesting that this technique can greatly mitigate the impact of parametric instabilities in advanced detectors.

  1. Climatic, parametric and non-parametric analysis of energy performance of double-glazed windows in different climates

    Directory of Open Access Journals (Sweden)

    Saeed Banihashemi

    2015-12-01

    Full Text Available In line with the growing global trend toward energy efficiency in buildings, this paper aims to first; investigate the energy performance of double-glazed windows in different climates and second; analyze the most dominant used parametric and non-parametric tests in dimension reduction for simulating this component. A four-story building representing the conventional type of residential apartments for four climates of cold, temperate, hot-arid and hot-humid was selected for simulation. 10 variables of U-factor, SHGC, emissivity, visible transmittance, monthly average dry bulb temperature, monthly average percent humidity, monthly average wind speed, monthly average direct solar radiation, monthly average diffuse solar radiation and orientation constituted the parameters considered in the calculation of cooling and heating loads of the case. Design of Experiment and Principal Component Analysis methods were applied to find the most significant factors and reduction dimension of initial variables. It was observed that in two climates of temperate and hot-arid, using double glazed windows was beneficial in both cold and hot months whereas in cold and hot-humid climates where heating and cooling loads are dominant respectively, they were advantageous in only those dominant months. Furthermore, an inconsistency was revealed between parametric and non-parametric tests in terms of identifying the most significant variables.

  2. Motion of an elastic capsule in a square microfluidic channel.

    Science.gov (United States)

    Kuriakose, S; Dimitrakopoulos, P

    2011-07-01

    In the present study we investigate computationally the steady-state motion of an elastic capsule along the centerline of a square microfluidic channel and compare it with that in a cylindrical tube. In particular, we consider a slightly over-inflated elastic capsule made of a strain-hardening membrane with comparable shearing and area-dilatation resistance. Under the conditions studied in this paper (i.e., small, moderate, and large capsules at low and moderate flow rates), the capsule motion in a square channel is similar to and thus governed by the same scaling laws with the capsule motion in a cylindrical tube, even though in the channel the cross section in the upstream portion of large capsules is nonaxisymmetric (i.e., square-like with rounded corners). When the hydrodynamic forces on the membrane increase, the capsule develops a pointed downstream edge and a flattened rear (possibly with a negative curvature) so that the restoring tension forces are increased as also happens with droplets. Membrane tensions increase significantly with the capsule size while the area near the downstream tip is the most probable to rupture when a capsule flows in a microchannel. Because the membrane tensions increase with the interfacial deformation, a suitable Landau-Levich-Derjaguin-Bretherton analysis reveals that the lubrication film thickness h for large capsules depends on both the capillary number Ca and the capsule size a; our computations determine the latter dependence to be (in dimensionless form) h ~ a(-2) for the large capsules studied in this work. For small and moderate capsule sizes a, the capsule velocity Ux and additional pressure drop ΔP+ are governed by the same scaling laws as for high-viscosity droplets. The velocity and additional pressure drop of large thick capsules also follow the dynamics of high-viscosity droplets, and are affected by the lubrication film thickness. The motion of our large thick capsules is characterized by a Ux-U ~ h ~ a(-2

  3. Proposal for a Casimir-driven parametric amplifier

    CERN Document Server

    Imboden, M; Campbell, D K; Bishop, D J

    2014-01-01

    In this paper, we discuss a design for a MEMS parametric amplifier modulated by the Casimir force. We present the theory for such a device and show that it allows for the implementation of a very sensitive voltage measuring technique, where the amplitude of a high quality factor resonator includes a tenth power dependency on an applied DC voltage. This approach opens up a new and powerful measuring modality, applicable to other measurement types.

  4. A parametric visualization software for the assignment problem

    Directory of Open Access Journals (Sweden)

    Papamanthou Charalampos

    2005-01-01

    Full Text Available In this paper we present a parametric visualization software used to assist the teaching of the Network Primal Simplex Algorithm for the assignment problem (AP. The assignment problem is a special case of the balanced transportation problem. The main functions of the algorithm and design techniques are also presented. Through this process, we aim to underline the importance and necessity of using such educational methods in order to improve the teaching of Computer Algorithms.

  5. A Parametric Modelling Method for Dexterous Finger Reachable Workspaces

    OpenAIRE

    2016-01-01

    The well-known algorithms, such as the graphic method, analytical method or numerical method, have some defects when modelling the dexterous finger workspace, which is a significant kinematical feature of dexterous hands and valuable for grasp planning, motion control and mechanical design. A novel modelling method with convenient and parametric performances is introduced to generate the dexterous-finger reachable workspace. This method constructs the geometric topology of the dexterous-finge...

  6. Capsule formation and asymbiotic seed germination in some hybrids of Phalaenopsis, influenced by pollination season and capsule maturity.

    Science.gov (United States)

    Balilashaki, Khosro; Gantait, Saikat; Naderi, Roohangiz; Vahedi, Maryam

    2015-07-01

    We explored the influence of pollination season and maturity of capsule on post-pollination capsule formation and in vitro asymbiotic seed germination, respectively. Three Phalaenopsis orchid hybrids, namely, 'Athens', 'Moscow' and 'Lusaka' flowers were artificially self-pollinated during winter, spring, summer and fall seasons and the impact of the pollination seasons was evident during capsule formation. It was observed that winter was the most suitable season for pollination of all the three Phalanaeopsis hybrids resulting in 80-88 % capsule formation. During summer, the pollination success rate was 24-28 %, but resulted in successful capsule formation. Season of pollination further delimited the germination efficiency of seeds harvested from capsules of variable maturity levels. Invariably, seeds collected from winter-pollinated capsules performed best in germination compared to other seasons, for instance, 'Moscow' seeds took less than 14 days to germinate from capsules developed following winter-pollination. Regarding the influence of capsule maturity on seed germination, we observed that seeds derived from 5-month mature capsules, invariably took least time to germinate than that of the 3-month or 7-month in all three hybrids, e.g., for 'Moscow' it was 13.9 days with a maximum of 90.3 % germination.

  7. Parametric and Non-Parametric Vibration-Based Structural Identification Under Earthquake Excitation

    Science.gov (United States)

    Pentaris, Fragkiskos P.; Fouskitakis, George N.

    2014-05-01

    ]. Preliminary results indicate that parametric methods are capable of sufficiently providing the structural/modal characteristics such as natural frequencies and damping ratios. The study also aims - at a further level of investigation - to provide a reliable statistically-based methodology for structural health monitoring after major seismic events which potentially cause harming consequences in structures. Acknowledgments This work was supported by the State Scholarships Foundation of Hellas. References [1] J. S. Sakellariou and S. D. Fassois, "Stochastic output error vibration-based damage detection and assessment in structures under earthquake excitation," Journal of Sound and Vibration, vol. 297, pp. 1048-1067, 2006. [2] G. Hloupis, I. Papadopoulos, J. P. Makris, and F. Vallianatos, "The South Aegean seismological network - HSNC," Adv. Geosci., vol. 34, pp. 15-21, 2013. [3] F. P. Pentaris, J. Stonham, and J. P. Makris, "A review of the state-of-the-art of wireless SHM systems and an experimental set-up towards an improved design," presented at the EUROCON, 2013 IEEE, Zagreb, 2013. [4] S. D. Fassois, "Parametric Identification of Vibrating Structures," in Encyclopedia of Vibration, S. G. Braun, D. J. Ewins, and S. S. Rao, Eds., ed London: Academic Press, London, 2001. [5] S. D. Fassois and J. S. Sakellariou, "Time-series methods for fault detection and identification in vibrating structures," Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, vol. 365, pp. 411-448, February 15 2007.

  8. A four spiral slots microstrip patch antenna for radiotelemetry capsules based on FDTD

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Antenna is very crucial to radiotelemetry capsules which can measure the physiological parameters of the gastrointestinal (GI) tract. The objective of this paper is to design a novel spiral slots microstrip patch antenna for the radiotelemetry capsules communicating with external recorder at 915 MHz located in ISM (Industry, Science, and Medical) bands. The microstrip patch antenna is designed and evaluated using the finite-difference time-domain (FDTD) method. Return loss characteristics and the effect of the human body on resonant frequency are analyzed, and the performances of radiation patterns at different positions of the human alimentary tract are also estimated. Finally, specific absorption rate (SAR) computations are performed, and the peak 1-g and 10-g SAR values are calculated. According to the peak SAR values, the maximum delivered power for the designed antenna was found so that the SAR values of the antenna satisfy the ANSI (American National Standards Institute) limitations.

  9. Illumination uniformity of capsules directly driven by a facility with thousands of laser beams

    Directory of Open Access Journals (Sweden)

    Temporal M.

    2013-11-01

    Full Text Available The uniformity of the illumination of a spherical capsule directly driven by laser beams has been assessed numerically. Different schemes characterized by ND = 12, 20, 32, 48 and 60 directions of irradiation associated to a single laser beam or a bundle of NB laser beams have been considered. The laser beams intensity profile is assumed super-Gaussian and the calculations take into account for beam imperfections as power imbalance and pointing errors. These facilities are characterized by a large number of laser beams Ntot = NDxNB. Assuming relatively small laser beams with an energy of a few hundred of J (200 J–500 J it turn out that a few thousand of beamlets (1000–5000 are needed in order to provide a total energy of 0.5–1 MJ. A large parametric study has been performed showing that the optimum laser intensity profile, which minimizes the root-mean-square deviation of the capsule illumination, depends on the values of the power imbalance and pointing error. Moreover, when beams imperfections are taken into account it is found that the uniformity of the illumination is almost the same for all facilities and only depends on the total number of laser beams Ntot.

  10. Role of shocks and mix caused by capsule defects

    Science.gov (United States)

    Bradley, P. A.; Cobble, J. A.; Tregillis, I. L.; Schmitt, M. J.; Obrey, K. D.; Glebov, V.; Batha, S. H.; Magelssen, G. R.; Fincke, J. R.; Hsu, S. C.; Krasheninnikova, N. S.; Murphy, T. J.; Wysocki, F. J.

    2012-09-01

    An Eulerian code with a turbulent mix model is used to model a set of plastic (CH) ablator capsules with and without equatorial grooves. The "perfect" capsule results were used to calibrate simulations of capsules with equatorial grooves of different depths that provided information on increasingly perturbed implosions. Simulations with a turbulence model were able to calculate the same yield over mix (YOM) ratio (experiment/mix simulation) of 0.2 to 0.3 for thin (8-μm thick) and thick shell (15-μm thick) capsules with no grooves and thin capsules with shallow grooves. When the capsules have deep grooves, the YOM ratio increases to greater than unity, probably because the deformed shocks focus too strongly on the symmetry axis in our two-dimensional simulations. This is supported by a comparison of simulated and experimental x-ray images.

  11. Expanding role of capsule endoscopy in inflammatory bowel disease

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Capsule endoscopy has been shown to detect small bowel inflammatory changes better than any other imaging modality. Selection criteria have been optimized to increase the yield of capsule endoscopy in patients suspected to have Crohn's disease. Capsule endoscopy allows for earlier diagnosis of Crohn's disease of the small bowel and improved diagnosis of colitis in patients where it is unclear if they suffer from Crohn's or ulcerative colitis. A test capsule is available to assess for small bowel strictures and thus avoid capsule retention. A common language has been developed and a new scoring index will be added to capsule software. It is envisioned that the manner in which we treat Crohn's disease in the future will change, based on earlier diagnosis and treatment aimed at mucosal healing rather than symptom improvement.

  12. Analysis Of Wetted-Foam ICF Capsule Perormance

    Science.gov (United States)

    Peterson, R.; Olson, R.; Zylstra, A.; Haines, B.; Yi, A.; Bradley, P.; Yin, L.; Leeper, R.; Kline, J.

    2016-10-01

    The performance of wetted-foam ICF capsules is investigated with the RAGE Eulerian radiation-hydrodynamics computer code. We are developing an experimental platform on NIF that employs a wetted foam liquid DT fuel layer ICF capsules. By varying the capsule temperature, the vapor density in the capsule can be prescribed, and the hot spot convergence ratio (CR) of the capsule implosion can be controlled. This allows us to investigate the fidelity of RAGE in modeling of capsule implosions as the value of CR is varied. In the NIF experiments, CR can be varied from 12 to 25. This presentation will cover simulations with RAGE of three NIF shots performed in 2016; a DD and a DT liquid fuel shot with CR =14 and a DT shot with CR =16. It will also discuss analysis of future experiments. This work was performed under auspices of the U. S. DOE by LANL.

  13. Observation of Parametric Instability in Advanced LIGO

    CERN Document Server

    Evans, Matthew; Fritschel, Peter; Miller, John; Barsotti, Lisa; Martynov, Denis; Brooks, Aidan; Coyne, Dennis; Abbott, Rich; Adhikari, Rana; Arai, Koji; Bork, Rolf; Kells, Bill; Rollins, Jameson; Smith-Lefebvre, Nicolas; Vajente, Gabriele; Yamamoto, Hiroaki; Derosa, Ryan; Effler, Anamaria; Kokeyama, Keiko; Betzweiser, Joseph; Frolov, Valera; Mullavey, Adam; O`Reilly, Brian; Dwyer, Sheila; Izumi, Kiwamu; Kawabe, Keita; Landry, Michael; Sigg, Daniel; Ballmer, Stefan; Massinger, Thomas J; Staley, Alexa; Mueller, Chris; Grote, Hartmut; Ward, Robert; King, Eleanor; Blair, David; Ju, Li; Zhao, Chunnong

    2015-01-01

    Parametric instabilities have long been studied as a potentially limiting effect in high-power interferometric gravitational wave detectors. Until now, however, these instabilities have never been observed in a kilometer-scale interferometer. In this work we describe the first observation of parametric instability in an Advanced LIGO detector, and the means by which it has been removed as a barrier to progress.

  14. Parametric form of QCD travelling waves

    OpenAIRE

    Peschanski, R.

    2005-01-01

    We derive parametric travelling-wave solutions of non-linear QCD equations. They describe the evolution towards saturation in the geometric scaling region. The method, based on an expansion in the inverse of the wave velocity, leads to a solvable hierarchy of differential equations. A universal parametric form of travelling waves emerges from the first two orders of the expansion.

  15. Nonlinear parametric instability of wind turbine wings

    DEFF Research Database (Denmark)

    Larsen, Jesper Winther; Nielsen, Søren R.K.

    2006-01-01

    Nonlinear rotor dynamic is characterized by parametric excitation of both linear and nonlinear terms caused by centrifugal and Coriolis forces when formulated in a moving frame of reference. Assuming harmonically varying support point motions from the tower, the nonlinear parametric instability...

  16. Computational Hypersonic Aerodynamics with Emphasis on Earth Reentry Capsules

    Directory of Open Access Journals (Sweden)

    Mihai Leonida NICULESCU

    2016-09-01

    Full Text Available The temperature in the front region of a hypersonic vehicle nose can be extremely high, for example, reaching approximately 11 000 K at a Mach number of 36 (Apollo reentry due to the bow shock wave. In this case, accurate prediction of temperature behind the shock wave is necessary in order to precisely estimate the wall heat flux. A better prediction of wall heat flux leads to smaller safety coefficient for thermal shield of space reentry vehicle; therefore, the size of thermal shield decreases and the payload could increase. However, the accurate prediction of temperature behind the bow shock wave implies the use of a precise chemical model whose partial differential equations are added to Navier-Stokes equations. This second order partial differential system is very difficult to be numerically integrated. For this reason, the present paper deals with the computational hypersonic aerodynamics with chemical reactions with the aim of supporting Earth reentry capsule design.

  17. Portable wireless power transmission system for video capsule endoscopy.

    Science.gov (United States)

    Zhiwei, Jia; Guozheng, Yan; Bingquan, Zhu

    2014-10-01

    Wireless power transmission is considered a practical way of overcoming the power shortage of wireless capsule endoscopy (VCE). However, most patients cannot tolerate the long hours of lying in a fixed transmitting coil during diagnosis. To develop a portable wireless power transmission system for VCE, a compact transmitting coil and a portable inverter circuit driven by rechargeable batteries are proposed. The couple coils, optimized considering the stability and safety conditions, are 28 turns of transmitting coil and six strands of receiving coil. The driven circuit is designed according to the portable principle. Experiments show that the integrated system could continuously supply power to a dual-head VCE for more than 8 h at a frame rate of 30 frames per second with resolution of 320 × 240. The portable VCE exhibits potential for clinical applications, but requires further improvement and tests.

  18. Parametrization of nuclear parton distributions

    Indian Academy of Sciences (India)

    M Hirai; S Kumano; M Miyama

    2001-08-01

    Optimum nuclear parton distributions are obtained by analysing available experimental data on electron and muon deep inelastic scattering (DIS). The distributions are given at 2 = 1 GeV2 with a number of parameters, which are determined by a 2 analysis of the data. Valencequark distributions are relatively well determined at medium , but they are slightly dependent on the assumed parametrization form particularly at small . Although antiquark distributions are shadowed at small , their behavior is not obvious at medium from the 2 data. The gluon distributions could not be restricted well by the inclusive DIS data; however, the analysis tends to support the gluon shadowing at small . We provide analytical expressions and computer subroutines for calculating the nuclear parton distributions, so that other researchers could use them for applications to other high-energy nuclear reactions.

  19. APT cost scaling: Preliminary indications from a Parametric Costing Model (PCM)

    Energy Technology Data Exchange (ETDEWEB)

    Krakowski, R.A.

    1995-02-03

    A Parametric Costing Model has been created and evaluate as a first step in quantitatively understanding important design options for the Accelerator Production of Tritium (APT) concept. This model couples key economic and technical elements of APT in a two-parameter search of beam energy and beam power that minimizes costs within a range of operating constraints. The costing and engineering depth of the Parametric Costing Model is minimal at the present {open_quotes}entry level{close_quotes}, and is intended only to demonstrate a potential for a more-detailed, cost-based integrating design tool. After describing the present basis of the Parametric Costing Model and giving an example of a single parametric scaling run derived therefrom, the impacts of choices related to resistive versus superconducting accelerator structures and cost of electricity versus plant availability ({open_quotes}load curve{close_quotes}) are reported. Areas of further development and application are suggested.

  20. Free-form geometric modeling by integrating parametric and implicit PDEs.

    Science.gov (United States)

    Du, Haixia; Qin, Hong

    2007-01-01

    Parametric PDE techniques, which use partial differential equations (PDEs) defined over a 2D or 3D parametric domain to model graphical objects and processes, can unify geometric attributes and functional constraints of the models. PDEs can also model implicit shapes defined by level sets of scalar intensity fields. In this paper, we present an approach that integrates parametric and implicit trivariate PDEs to define geometric solid models containing both geometric information and intensity distribution subject to flexible boundary conditions. The integrated formulation of second-order or fourth-order elliptic PDEs permits designers to manipulate PDE objects of complex geometry and/or arbitrary topology through direct sculpting and free-form modeling. We developed a PDE-based geometric modeling system for shape design and manipulation of PDE objects. The integration of implicit PDEs with parametric geometry offers more general and arbitrary shape blending and free-form modeling for objects with intensity attributes than pure geometric models.

  1. Generalized Parametrization Dependence in Quantum Gravity

    CERN Document Server

    Gies, Holger; Lippoldt, Stefan

    2015-01-01

    We critically examine the gauge, and field-parametrization dependence of renormalization group flows in the vicinity of non-Gau\\ss{}ian fixed points in quantum gravity. While physical observables are independent of such calculational specifications, the construction of quantum gravity field theories typically relies on off-shell quantities such as $\\beta$ functions and generating functionals and thus face potential stability issues with regard to such generalized parametrizations. We analyze a two-parameter class of covariant gauge conditions, the role of momentum-dependent field rescalings and a class of field parametrizations. Using the product of Newton and cosmological constant as an indicator, the principle of minimum sensitivity identifies stationary points in this parametrization space which show a remarkable insensitivity to the parametrization. In the most insensitive cases, the quantized gravity system exhibits a non-Gau\\ss{}ian UV stable fixed point, lending further support to asymptotically free q...

  2. Reaction-in-flight neutrons as a signature for shell mixing in National Ignition Facility capsules

    Science.gov (United States)

    Hayes, A. C.; Bradley, P. A.; Grim, G. P.; Jungman, Gerard; Wilhelmy, J. B.

    2010-01-01

    Analytic calculations and results from computational simulations are presented that suggest that reaction-in-flight (RIF) neutrons can be used to diagnose mixing of the ablator shell material into the fuel in deuterium-tritium (DT) capsules designed for the National Ignition Facility (NIF) [J. A. Paisner, J. D. Boyes, S. A. Kumpan, W. H. Lowdermilk, and M. S. Sorem, Laser Focus World 30, 75 (1994)]. Such mixing processes in NIF capsules are of fundamental physical interest and can have important effects on capsule performance, quenching the total thermonuclear yield. The sensitivity of RIF neutrons to hydrodynamical mixing arises through the dependence of RIF production on charged-particle stopping lengths in the mixture of DT fuel and ablator material. Since the stopping power in the plasma is a sensitive function of the electron temperature and density, it is also sensitive to mix. RIF production scales approximately inversely with the degree of mixing taking place, and the ratio of RIF to down-scattered neutrons provides a measure of the mix fraction and/or the mixing length. For sufficiently high-yield capsules, where spatially resolved RIF images may be possible, neutron imaging could be used to map RIF images into detailed mix images.

  3. A pharmacokinetic comparison of the modified release capsule and a plain tablet formulation of mebeverine.

    Science.gov (United States)

    Winsemius, A; Meuwsen, I M; Boon, C; van der Laan, A; Brekle, A; de Vries, M

    2002-11-01

    This study was conducted to compare the pharmacokinetic properties of the modified release 200 mg capsule of mebeverine and the plain 135 mg tablet of mebeverine after single and multiple doses in 12 healthy subjects in a randomised, crossover design. Single doses were given on days 1 and 7 and multiple doses (200 mg b.i.d. for the capsule and 135 mg t.i.d. for the tablet) on days 2-6 of the study. The 200 mg modified release capsule of mebeverine has extended release properties, as indicated by a lower Cmax, a later tmax and a longer elimination half-life than the plain tablet, while the bioavailability is optimal. No significant accumulation occurs after multiple doses of either formulation. The twice-daily dosage regimen of the 200 mg modified release capsule is a good alternative to the three times daily dosage regimen of the 135 mg plain tablet, because the reduced daily intake is likely to benefit patient compliance.

  4. Small intestinal model for electrically propelled capsule endoscopy

    Directory of Open Access Journals (Sweden)

    Woo Sang Hyo

    2011-12-01

    Full Text Available Abstract The aim of this research is to propose a small intestine model for electrically propelled capsule endoscopy. The electrical stimulus can cause contraction of the small intestine and propel the capsule along the lumen. The proposed model considered the drag and friction from the small intestine using a thin walled model and Stokes' drag equation. Further, contraction force from the small intestine was modeled by using regression analysis. From the proposed model, the acceleration and velocity of various exterior shapes of capsule were calculated, and two exterior shapes of capsules were proposed based on the internal volume of the capsules. The proposed capsules were fabricated and animal experiments were conducted. One of the proposed capsules showed an average (SD velocity in forward direction of 2.91 ± 0.99 mm/s and 2.23 ± 0.78 mm/s in the backward direction, which was 5.2 times faster than that obtained in previous research. The proposed model can predict locomotion of the capsule based on various exterior shapes of the capsule.

  5. Kinematics Analysis and Parametric Design of a Walking Mechanism of Bionic Biped Water-Walking Robot%仿生双足水上行走机器人行走机构的运动学分析及参数化设计

    Institute of Scientific and Technical Information of China (English)

    曹凯; 徐林森; 沈惠平; 魏鲜明

    2013-01-01

    A walking mechanism of bionic biped water -walking robot is designed; educing the equations of the location, velocity, and acceleration of two feet mass sports center. To simulate the foot trajectory of basilisk lizard's, the foot rod and the horizontal plane angle curve is taken as the objective of parameter design, and the influences of the foot rod bar length change to the foot rid and the horizontal plane angle is analyzed through the software. The walking mechanism is parametric designed by analyzing the influential factors of sensitivity. Finally the parametric designed mechanism is simulated, and the simulation results show that the movement of this bionic walking mechanism can meet the basilisk lizards 'foot trajectory.%设计了仿生双足水上行走机器人行走机构,通过运动学分析导出了两脚掌质心的运动轨迹方程、速度及加速度方程;以模拟蛇怪蜥蜴脚掌的运动轨迹为目标,以脚杆与水平面的夹角曲线作为目标进行参数化设计,通过软件分析得到了各部分杆长变化对脚杆与水平面的夹角的影响,经过分析影响因素的敏感度,对机构进行参数化设计.最后对参数化设计的机构进行仿真分析,仿真结果表明,该仿生机构脚杆的运动能够满足蛇怪蜥蜴脚掌的运动轨迹.

  6. Implementation of the intelligent and continuous optimization method in underground engineering,PartⅠ. Parametric design and optimization method%地下工程智能连续优化方法的实现Ⅰ:参数化设计及优化方法

    Institute of Scientific and Technical Information of China (English)

    王辉; 陈卫忠; 李廷春; 王清标

    2014-01-01

    地下工程空间分布优化设计是大型地下工程稳定性分析的关键。如今,制约其发展的瓶颈主要有两个:一是模型的建立;二是优化方法的实现。针对以上问题,以大型有限元软件ABAQUS为平台,基于其标准设计语言Python对其前后处理进行二次开发,将参数化模型可动边界的非线性关系编入到程序中,实现了有限元参数化设计;通过MATLAB语言编程,建立基于Nelder-Mead法与精确罚函数法的联合优化方法,并将优化分析程序与有限元参数化设计相结合,实现了地下工程问题的“智能连续”优化。文中涉及到工程应用将在本文的Ⅱ部分给出。%The optimization design of underground engineering space distribution is the key of stability anal-ysis in a large-scale underground engineering. Nowadays, there are two main bottlenecks to restrict its de-velopment. One is the problem of model establishing and the other is the implementation of the optimiza-tion method. Taking the general-purpose finite element software ABAQUS as a platform, its standard design language Python is used to make secondary development for the pre-processing and post-processing. The moving boundary nonlinear relationship of parametric model is made into the program to realize the fem-based parametric design. Using MATLAB language for programming,a combined optimization was estab-lished on the basis of Nelder-Mead algorithm and exact penalty function method, and further combining the optimum analysis program with finite element parametric design, the intelligent and continuous optimiza-tion method in underground engineering has been realized. The engineering application involved in this pa-per will be given in Part Ⅱ of this paper series.

  7. New reduced volume preparation regimen in colon capsule endoscopy

    Institute of Scientific and Technical Information of China (English)

    Yasuo Kakugawa; Kazuhide Higuchi; Shinji Tanaka; Hideki Ishikawa; Hisao Tajiri; Yutaka Saito; Shoichi Saito; Kenji Watanabe; Naoki Ohmiya; Mitsuyuki Murano; Shiro Oka; Tetsuo Arakawa; Hidemi Goto

    2012-01-01

    AIM:To evaluate the effectiveness of our proposed bowel preparation method for colon capsule endoscopy.METHODS:A pilot,multicenter,randomized controlled trial compared our proposed "reduced volume method" (group A) with the "conventional volume method" (group B) preparation regimens.Group A did not drink polyethylene glycol electrolyte lavage solution (PEGELS) the day before the capsule procedure,while group B drank 2 L.During the procedure day,groups A and B drank 2 L and 1 L of PEG-ELS,respectively,and swallowed the colon capsule (PillCam COLON(R) capsule).Two hours later the first booster of 100 g magnesium citrate mixed with 900 mL water was administered to both groups,and the second booster was administered six hours post capsule ingestion as long as the capsule had not been excreted by that time.Capsule videos were reviewed for grading of cleansing level.RESULTS:Sixty-four subjects were enrolled,with results from 60 analyzed.Groups A and B included 31 and 29 subjects,respectively.Twenty-nine (94%) subjects in group A and 25 (86%) subjects in group B had adequate bowel preparation (ns).Twenty-two (71%) of the 31 subjects in group A excreted the capsule within its battery life compared to 16 (55%) of the 29 subjects in group B (ns).Of the remaining 22 subjects whose capsules were not excreted within the battery life,all of the capsules reached the left side colon before they stopped functioning.A single adverse event was reported in one subject who had mild symptoms of nausea and vomiting one hour after starting to drink PEG-ELS,due to ingesting the PEG-ELS faster than recommended.CONCLUSION:Our proposed reduced volume bowel preparation method for colon capsule without PEG-ELS during the days before the procedure was as effective as the conventional volume method.

  8. 21 CFR 876.1300 - Ingestible telemetric gastrointestinal capsule imaging system.

    Science.gov (United States)

    2010-04-01

    ... § 876.1300 Ingestible telemetric gastrointestinal capsule imaging system. (a) Identification. An ingestible telemetric gastrointestinal capsule imaging system is used for visualization of the small bowel... Special Controls Guidance Document: Ingestible Telemetric Gastrointestinal Capsule Imaging Systems;...

  9. The intake of long chain omega 3 fatty acids through fish versus capsules results in greater increments of their plasma levels

    Directory of Open Access Journals (Sweden)

    Visioli Francesco

    2004-03-01

    Full Text Available Omega 3 fatty acids from fish appear to be more cardioprotective than equivalent amounts provided as capsules. We gave volunteers, for six weeks, either 100 g\\\\day of salmon, providing 383 mg of EPA and 544 mg of DHA or one or three capsules of fish oil\\\\day, providing 150 mg of EPA and 106 mg of DHA or 450 mg of EPA and 318 mg of DHA. We also re-evaluated data from a previous study carried out with the same design. Marked increments in plasma EPA and DHA concentrations (μg\\\\mg total lipid and percentages of total fatty acids were recorded at the end of either treatment. Such increments were linearly and significantly correlated with the dose after capsule administration. Notably, increments in plasma EPA and DHA concentration after salmon intake were significantly higher than after administration of capsules. In fact, the same increments would be obtained with at least two- and nine-fold higher doses of EPA and DHA, respectively, if administered with capsules rather than salmon. In turn, we provide experimental evidence that omega 3 fatty acids from fish are more effectively incorporated into plasma lipids than when administered as capsules and that increments in plasma concentrations of EPA and DHA given as capsules are linearly correlated with their intakes.

  10. Visualization of Capsule Reentry Vehicle Heat Shield Ablation Using Naphthalene PLIF

    Science.gov (United States)

    Combs, Christopher S.; Clemens, Noel T.; Danehy, Paul M.

    2014-01-01

    The Orion Multi-Purpose Crew Vehicle (MPCV) will use an ablative heat shield and improved understanding of the ablation process would be beneficial for design purposes. Given that ablation is a multi-physics process involving heat and mass transfer, codes aiming to predict heat shield ablation are in need of experimental data pertaining to the turbulent transport of ablation products for validation. At The University of Texas at Austin, a technique is being developed that uses planar laser-induced fluorescence (PLIF) of a low-temperature sublimating ablator (naphthalene) to visualize the transport of ablation products in a supersonic flow. Since ablation at reentry temperatures can be difficult to recreate in a laboratory setting it is desirable to create a limited physics problem and simulate the ablation process at relatively low temperature conditions using naphthalene. A scaled Orion MPCV model with a solid naphthalene heat shield has been tested in a Mach 5 wind tunnel at various angles of attack in the current work. PLIF imaging reveals the distribution of the ablation products as they are transported into the heat-shield boundary layer and over the capsule shoulders into the separated shear layer and backshell recirculation region. Visualizations of the capsule shear layer using both naphthalene PLIF and Schlieren imaging compared favorably. High concentrations of naphthalene in the capsule separated flow region, intermittent turbulent structures on the heat shield surface, and interesting details of the capsule shear layer structure were observed using the naphthalene PLIF technique. The capsule shear layer was also shown to generally appear to be more turbulent at lower angles of attack. Furthermore, the PLIF signal increased steadily over the course of a run indicating that during a wind tunnel run the model heated up and the rate of naphthalene ablation increased. The shear layer showed increasing signs of turbulence over the course of a wind tunnel run

  11. Airy beam optical parametric oscillator.

    Science.gov (United States)

    Aadhi, A; Chaitanya, N Apurv; Jabir, M V; Vaity, Pravin; Singh, R P; Samanta, G K

    2016-05-04

    Airy beam, a non-diffracting waveform, has peculiar properties of self-healing and self-acceleration. Due to such unique properties, the Airy beam finds many applications including curved plasma wave-guiding, micro-particle manipulation, optically mediated particle clearing, long distance communication, and nonlinear frequency conversion. However, many of these applications including laser machining of curved structures, generation of curved plasma channels, guiding of electric discharges in a curved path, study of nonlinear propagation dynamics, and nonlinear interaction demand Airy beam with high power, energy, and wavelength tunability. Till date, none of the Airy beam sources have all these features in a single device. Here, we report a new class of coherent sources based on cubic phase modulation of a singly-resonant optical parametric oscillator (OPO), producing high-power, continuous-wave (cw), tunable radiation in 2-D Airy intensity profile existing over a length >2 m. Based on a MgO-doped periodically poled LiNbO3 crystal pumped at 1064 nm, the Airy beam OPO produces output power more than 8 W, and wavelength tunability across 1.51-1.97 μm. This demonstration gives new direction for the development of sources of arbitrary structured beams at any wavelength, power, and energy in all time scales (cw to femtosecond).

  12. Potassium iodide capsule treatment of feline sporotrichosis.

    Science.gov (United States)

    Reis, Erica G; Gremião, Isabella D F; Kitada, Amanda A B; Rocha, Raphael F D B; Castro, Verônica S P; Barros, Mônica B L; Menezes, Rodrigo C; Pereira, Sandro A; Schubach, Tânia M P

    2012-06-01

    Sporotrichosis is a mycosis caused by Sporothrix schenckii. The most affected animal is the cat; it has played an important role in the zoonotic transmission of this disease, especially in Rio de Janeiro, Brazil, since 1998. In order to evaluate the treatment of feline sporotrichosis with potassium iodide, an observational cohort was conducted in 48 cats with sporotrichosis at Instituto de Pesquisa Clínica Evandro Chagas, Fiocruz. All cats received potassium iodide capsules, 2.5 mg/kg to 20 mg/kg q24h. The cure rate was 47.9%, treatment failure was 37.5%, treatment abandonment was 10.4% and death was 4.2%. Clinical adverse effects were observed in 52.1% of the cases. Thirteen cats had a mild increase in hepatic transaminase levels during the treatment, six of them presented clinical signs suggestive of hepatotoxicity. Compared to previous studies with itraconazole and iodide in saturated solution, potassium iodide capsules are an alternative for feline sporotrichosis treatment.

  13. Parametrization of $\\epsilon$-rational curves: error analysis

    CERN Document Server

    Rueda, Sonia L

    2010-01-01

    In [Computer Aided Geometric Design 27 (2010), 212-231] the authors present an algorithm to parametrize approximately $\\epsilon$-rational curves, and they show in 2 examples that the Hausdorff distance, w.r.t. to the Euclidean distance, between the input and output curves is small. In this paper, we analyze this distance for a whole family of curves randomly generated and we automatize the strategy used in [Computer Aided Geometric Design 27 (2010), 212-231]. We find a reasonable upper bound of the Hausdorff distance between each input and output curve of the family.

  14. Parametric testing of a linearly driven Stirling cryogenic refrigerator

    Science.gov (United States)

    Stolfi, F. R.; Daniels, A.

    1985-05-01

    The parametric testing of a novel Stirling cycle cryogenic refrigerator which incorporates electromagnetic bearings, clearance seals and electronically controlled linear motion was studied. The last feature, which involves the use of two linear motors, position transducers and a highly accurate electronic feedback network, produces the system capability which forms the basis for the tests. The test results provide designers with an understanding of the basic operation of the Stirling cycle and give potential users some indication of the capabilities of this refrigerator under off design conditions.

  15. Experimental measurement on movement of spiral-type capsule endoscope

    Directory of Open Access Journals (Sweden)

    Yang W

    2016-01-01

    Full Text Available Wanan Yang,1 Houde Dai,2 Yong He,1 Fengqing Qin1 1School of Computer and Information Engineering, Yibin University, Yibin, Sichuan, People's Republic of China; 2Quanzhou Institute of Equipment Manufacturing, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Quanzhou, People's Republic of China Abstract: Wireless capsule endoscope achieved great success, however, the maneuvering of wireless capsule endoscope is challenging at present. A magnetic driving instrument, including two bar magnets, a stepper motor, a motor driver, a motor controller, and a power supplier, was developed to generate rotational magnetic fields. Permanent magnet ring, magnetized as S and N poles radially and mounted spiral structure on the surface, acted as a capsule. The maximum torque passing to the capsule, rotational synchronization of capsule and motor, and the translational speed of capsule, were measured in ex vivo porcine large intestine. The experimental results illustrate that the rotational movement of the spiral-type capsule in the intestine is feasible and the cost of the magnetic driving equipment is low. As a result, the solution is promising in the future controllability. Keywords: wireless capsule endoscope, magnet ring, magnetic driving, spiral structure, torque  

  16. Experimental modulation of capsule size in Cryptococcus neoformans

    Directory of Open Access Journals (Sweden)

    Zaragoza Oscar

    2004-01-01

    Full Text Available Experimental modulation of capsule size is an important technique for the study of the virulence of the encapsulated pathogen Cryptococcus neoformans. In this paper, we summarize the techniques available for experimental modulation of capsule size in this yeast and describe improved methods to induce capsule size changes. The response of the yeast to the various stimuli is highly dependent on the cryptococcal strain. A high CO2 atmosphere and a low iron concentration have been used classically to increase capsule size. Unfortunately, these stimuli are not reliable for inducing capsular enlargement in all strains. Recently we have identified new and simpler conditions for inducing capsule enlargement that consistently elicited this effect. Specifically, we noted that mammalian serum or diluted Sabouraud broth in MOPS buffer pH 7.3 efficiently induced capsule growth. Media that slowed the growth rate of the yeast correlated with an increase in capsule size. Finally, we summarize the most commonly used media that induce capsule growth in C. neoformans.

  17. Quality evaluation of simvastatin compounded capsules

    Directory of Open Access Journals (Sweden)

    Flávia Dias Marques-Marinho

    2011-09-01

    Full Text Available Simvastatin is commercially available as tablets and compounded capsules in Brazil. Very few reports regarding these capsules' quality, and consequently their efficacy, are available. The pharmaceutical quality of 30 batches of 20 mg simvastatin capsules from the market was evaluated by weight determination, content uniformity, disintegration (Brazilian Pharmacopeia, assay and dissolution test (USP32 tablet monograph. A HPLC method was developed for assay, content uniformity and dissolution test, and specifications were also established. Out of the 30 batches evaluated, 29 showed capsule disintegration within 45 min and individual weight variation was within ±10% or ±7.5% relative to average weight, for 300 mg, respectively. Only 27 batches met dissolution test criteria with values >80% of the labeled amount in 45 min; 21 batches showed simvastatin content between 90.0-110.0% of the labeled amount and 19 batches had at least 9 out of 10 capsules with content uniformity values between 85.0-115.0% of the labeled amount with RSDNo Brasil, a sinvastatina está comercialmente disponível na forma de comprimidos e cápsulas manipuladas. Poucos relatos estão disponíveis sobre a qualidade e, consequentemente, a eficácia dessas cápsulas. A qualidade de 30 lotes de sinvastatina 20 mg cápsulas do mercado foi avaliada através da determinação de peso, uniformidade de conteúdo, desintegração (Farmacopéia Brasileira, doseamento e teste de dissolução (monografia comprimidos USP32. Método por CLAE foi desenvolvido para o doseamento, uniformidade de conteúdo e teste de dissolução; além disso, especificações foram estabelecidas. Dos 30 lotes avaliados, 29 apresentaram desintegração da cápsula até 45 min e a variação do peso individual foi ± 10% ou ± 7,5% em relação ao peso médio, se 300 mg, respectivamente. Apenas 27 lotes preencheram os critérios do teste de dissolução com valores > 80% da quantidade rotulada, em 45 min, 21

  18. Science Parametrics for TPF-Type Missions

    CERN Document Server

    Brown, Robert A

    2014-01-01

    We propose a science metric for pure-search missions of the scale of the Terrestrial Planet Finder. The metric is the expected number $N$ of discovered earthlike planets as a function of total exposure time $\\Sigma\\tau$. We estimate $N(\\Sigma\\tau)$ for a range of mission parameters: aperture $D=4-16$ m, inner working angle $IWA=0.0196''-0.3135''$, and $\\Sigma\\tau=10-1000$ d. Our technique involves (1) building a prioritized stack of all possible search observations of stars in the input catalog, including revisits, (2) constructing design reference missions by repeatedly selecting the observation with highest merit from the top of the stack, (3) estimating the density of $N$ by convolving the Bernoullian densities of executed observations, and (4) investigating the parametrical variations of $N$, $D$, $IWA$, and $\\Sigma\\tau$. For example, near the center of the range of parameters -- at $D=8$ m, $IWA=0.0784''$, $\\Sigma\\tau=100$ d -- we estimate $N=40$, that $N\\sim\\Sigma\\tau^{0.272}$, and that a factor-two imp...

  19. Macromechanical parametric amplification with a base-excited doubly clamped beam

    DEFF Research Database (Denmark)

    Neumeyer, Stefan; Thomsen, Jon Juel

    2013-01-01

    of steady-state vibration amplitude of the directly and parametrically excited system, to vibration amplitude of the directly excited only system. The nonlinear effect of midplane stretching is compared to the effects of nonlinear inertia and curvature. An approximate analytical expression for the vibration...... amplitude is derived. For a given small level of transverse displacement for both the cantilever and doubly clamped beam, the effect of midplane stretching is dominant compared to those caused by nonlinear inertia and curvature. It was found that the beam slenderness ratio can be used as an effective design......Parametric amplification is realized by adding parametric excitation to externally driven near-resonant oscillations. The effect of specific cubic nonlinearities on the parametrically amplified steady-state vibrations and gain is investigated theoretically. Here, gain is defined as the ratio...

  20. Analysis of Fission Products on the AGR-1 Capsule Components

    Energy Technology Data Exchange (ETDEWEB)

    Paul A. Demkowicz; Jason M. Harp; Philip L. Winston; Scott A. Ploger

    2013-03-01

    The components of the AGR-1 irradiation capsules were analyzed to determine the retained inventory of fission products in order to determine the extent of in-pile fission product release from the fuel compacts. This includes analysis of (i) the metal capsule components, (ii) the graphite fuel holders, (iii) the graphite spacers, and (iv) the gas exit lines. The fission products most prevalent in the components were Ag-110m, Cs 134, Cs 137, Eu-154, and Sr 90, and the most common location was the metal capsule components and the graphite fuel holders. Gamma scanning of the graphite fuel holders was also performed to determine spatial distribution of Ag-110m and radiocesium. Silver was released from the fuel components in significant fractions. The total Ag-110m inventory found in the capsules ranged from 1.2×10 2 (Capsule 3) to 3.8×10 1 (Capsule 6). Ag-110m was not distributed evenly in the graphite fuel holders, but tended to concentrate at the axial ends of the graphite holders in Capsules 1 and 6 (located at the top and bottom of the test train) and near the axial center in Capsules 2, 3, and 5 (in the center of the test train). The Ag-110m further tended to be concentrated around fuel stacks 1 and 3, the two stacks facing the ATR reactor core and location of higher burnup, neutron fluence, and temperatures compared with Stack 2. Detailed correlation of silver release with fuel type and irradiation temperatures is problematic at the capsule level due to the large range of temperatures experienced by individual fuel compacts in each capsule. A comprehensive Ag 110m mass balance for the capsules was performed using measured inventories of individual compacts and the inventory on the capsule components. For most capsules, the mass balance was within 11% of the predicted inventory. The Ag-110m release from individual compacts often exhibited a very large range within a particular capsule.

  1. A new endocapsular open ring for prevention of anterior and posterior capsule opacification

    Directory of Open Access Journals (Sweden)

    Pallikaris IG

    2016-11-01

    Full Text Available Ioannis G Pallikaris, Nela R Stojanovic, Harilaos S Ginis Institute of Vision and Optics, Department of Medicine, University of Crete, Heraklion, Crete, Greece Purpose: The aim of this study is to demonstrate the functionality of a new design of a thick endocapsular open ring for prevention of anterior capsule opacification (ACO and posterior capsule opacification (PCO. Setting: The Institute of Vision and Optics, University of Crete and University Hospital of Heraklion, Crete, Greece. Design: Prospective, interventional pilot study. Methods: Fifteen patients (17 eyes underwent cataract surgery with phacoemulsification. During surgery, a thick endocapsular open ring (peripheral capsule reconstructor was inserted into the capsular bag, prior to intraocular lens (IOL implantation. Six different models of IOL were implanted. Postoperatively, the degree of ACO and PCO was evaluated and described as none, mild, moderate, or severe. Results: The mean follow-up period was 30±8.06 months (range: 12–36 months. At the last follow-up, mild PCO was observed in only three eyes and mild ACO in three patients. The centration of IOLs was good in all but one eye, which had a tilted IOL. Conclusion: The results of this pilot study suggest that the implantation of a new design of thick endocapsular open ring is feasible and may contribute to the prevention of PCO and ACO after cataract surgery. Keywords: intraocular implant, cataract, phacoemulsification, silicone

  2. A new endocapsular open ring for prevention of anterior and posterior capsule opacification

    Science.gov (United States)

    Pallikaris, Ioannis G; Stojanovic, Nela R; Ginis, Harilaos S

    2016-01-01

    Purpose The aim of this study is to demonstrate the functionality of a new design of a thick endocapsular open ring for prevention of anterior capsule opacification (ACO) and posterior capsule opacification (PCO). Setting The Institute of Vision and Optics, University of Crete and University Hospital of Heraklion, Crete, Greece. Design Prospective, interventional pilot study. Methods Fifteen patients (17 eyes) underwent cataract surgery with phacoemulsification. During surgery, a thick endocapsular open ring (peripheral capsule reconstructor) was inserted into the capsular bag, prior to intraocular lens (IOL) implantation. Six different models of IOL were implanted. Postoperatively, the degree of ACO and PCO was evaluated and described as none, mild, moderate, or severe. Results The mean follow-up period was 30±8.06 months (range: 12–36 months). At the last follow-up, mild PCO was observed in only three eyes and mild ACO in three patients. The centration of IOLs was good in all but one eye, which had a tilted IOL. Conclusion The results of this pilot study suggest that the implantation of a new design of thick endocapsular open ring is feasible and may contribute to the prevention of PCO and ACO after cataract surgery. PMID:27843291

  3. Mitigating the impact of hohlraum asymmetries in National Ignition Facility implosions using capsule shims

    Science.gov (United States)

    Clark, D. S.; Weber, C. R.; Smalyuk, V. A.; Robey, H. F.; Kritcher, A. L.; Milovich, J. L.; Salmonson, J. D.

    2016-07-01

    Current indirect drive implosion experiments on the National Ignition Facility (NIF) [Moses et al., Phys. Plasmas 16, 041006 (2009)] are believed to be strongly impacted by long wavelength perturbations driven by asymmetries in the hohlraum x-ray flux. To address this perturbation source, active efforts are underway to develop modified hohlraum designs with reduced asymmetry imprint. An alternative strategy, however, is to modify the capsule design to be more resilient to a given amount of hohlraum asymmetry. In particular, the capsule may be deliberately misshaped, or "shimmed," so as to counteract the expected asymmetries from the hohlraum. Here, the efficacy of capsule shimming to correct the asymmetries in two recent NIF implosion experiments is assessed using two-dimensional radiation hydrodynamics simulations. Despite the highly time-dependent character of the asymmetries and the high convergence ratios of these implosions, simulations suggest that shims could be highly effective at counteracting current asymmetries and result in factors of a few enhancements in neutron yields. For higher compression designs, the yield improvement could be even greater.

  4. Mitigating the impact of hohlraum asymmetries in National Ignition Facility implosions using capsule shims

    Science.gov (United States)

    Clark, Daniel; Weber, Christopher; Smalyuk, Vladimir; Robey, Harry; Kritcher, Andrea; Milovich, Jose; Salmonson, Jay

    2016-10-01

    Current indirect drive implosion experiments on the National Ignition Facility (NIF) are believed to be strongly impacted by long wavelength perturbations driven by asymmetries in the hohlraum x-ray flux. To address this perturbation source, active efforts are underway to develop modified hohlraum designs with reduced asymmetry imprint. An alternative strategy, however, is to modify the capsule design to be more resilient to a given amount of hohlraum asymmetry. In particular, the capsule may be deliberately misshaped, or ``shimmed,'' so as to counteract the expected asymmetries from the hohlraum. Here, the efficacy of capsule shimming to correct the asymmetries in two recent NIF implosion experiments is assessed using two-dimensional radiation hydrodynamics simulations. Despite the highly time-dependent character of the asymmetries and the high convergence ratios of these implosions, simulations suggest that shims could be highly effective at counteracting current asymmetries and result in factors of a few enhancements in neutron yields. For higher compression designs, the yield improvement could be even greater. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  5. Creating Efficient Instrumentation Networks to Support Parametric Risk Transfer

    Science.gov (United States)

    Rockett, P.

    2009-04-01

    The development and institutionalisation of Catastrophe modelling during the 1990s opened the way for Catastrophe risk securitization transactions in which catastrophe risk held by insurers is transferred to the capital markets in the form of a bond. Cat Bonds have been one of the few areas of the capital markets in which the risk modelling has remained secure and the returns on the bonds have held up well through the 2008 Credit Crunch. There are three ways of structuring the loss triggers on bonds: ‘indemnity triggers' - reflecting the actual losses to the issuers; ‘index triggers' reflecting the losses to some index such as reported insurance industry loss and ‘parametric triggers' reflecting the parameters of the underlying catastrophe event itself. Indemnity triggers require that the investors trust that the insurer is reporting all their underlying exposures, while both indemnity and index losses may take 1-2 years to settle before all the claims are reported and resolved. Therefore parametric structures have many advantages, in particular in that the bond can be settled rapidly after an event. The challenge is to create parametric indices that closely reflect the actual losses to the insurer - ie that minimise ‘basis risk'. First generation parametric indices had high basis risk as they were crudely based on the magnitude of an earthquake occurring within some defined geographical box, or the intensity of a hurricane relative to the distance of the storm from some location. Second generation triggers involve taking measurements of ground motion or windspeed or flood depths at many locations and weighting each value so that the overall index closely mimics insurance loss. Cat bonds with second generation parametric triggers have been successfully issued for European Windstorm, UK Flood and California and Japan Earthquake. However the spread of second generation parametric structures is limited by the availability of suitable networks of

  6. Investigation for parametric vibration of rolling mill

    Institute of Scientific and Technical Information of China (English)

    唐华平; 丁睿; 吴运新; 钟掘

    2002-01-01

    The vibration unsteady condition of rolling mill caused by flexural vibration of strip has been investigated. The parametric flexural vibration equation of rolled strip has been established. The parametric flexural vibration stability of rolled strip has been studied and the regions of stability and unstability have been determined based on Floquet theory and perturbation method. The flexural-vibration of strip is unstable when the frequency of variable tension is two times as the natural frequency of flexural-vibration strip. The characteristic of current in a temp driving motor's main loop has been studied and tested, it has been proved that there are 6 harmonic component and 12 harmonic component in main loop of driving motor electricity. The vertical vibration of working roller has been tested, the test result approves that the running unsteady is caused by parametric vibration. It attaches importance to the parametric vibration of rolling mill.

  7. Conformally covariant parametrizations for relativistic initial data

    Science.gov (United States)

    Delay, Erwann

    2017-01-01

    We revisit the Lichnerowicz-York method, and an alternative method of York, in order to obtain some conformally covariant systems. This type of parametrization is certainly more natural for non constant mean curvature initial data.

  8. Parametrically disciplined operation of a vibratory gyroscope

    Science.gov (United States)

    Shcheglov, Kirill V. (Inventor); Hayworth, Ken J. (Inventor); Challoner, A. Dorian (Inventor); Peay, Chris S. (Inventor)

    2008-01-01

    Parametrically disciplined operation of a symmetric nearly degenerate mode vibratory gyroscope is disclosed. A parametrically-disciplined inertial wave gyroscope having a natural oscillation frequency in the neighborhood of a sub-harmonic of an external stable clock reference is produced by driving an electrostatic bias electrode at approximately twice this sub-harmonic frequency to achieve disciplined frequency and phase operation of the resonator. A nearly symmetric parametrically-disciplined inertial wave gyroscope that can oscillate in any transverse direction and has more than one bias electrostatic electrode that can be independently driven at twice its oscillation frequency at an amplitude and phase that disciplines its damping to zero in any vibration direction. In addition, operation of a parametrically-disciplined inertial wave gyroscope is taught in which the precession rate of the driven vibration pattern is digitally disciplined to a prescribed non-zero reference value.

  9. Robust and Efficient Parametric Face Alignment

    NARCIS (Netherlands)

    Tzimiropoulos, Georgios; Zafeiriou, Stefanos; Pantic, Maja

    2011-01-01

    We propose a correlation-based approach to parametric object alignment particularly suitable for face analysis applications which require efficiency and robustness against occlusions and illumination changes. Our algorithm registers two images by iteratively maximizing their correlation coefficient

  10. Parametric methods for spatial point processes

    DEFF Research Database (Denmark)

    Møller, Jesper

    (This text is submitted for the volume ‘A Handbook of Spatial Statistics' edited by A.E. Gelfand, P. Diggle, M. Fuentes, and P. Guttorp, to be published by Chapmand and Hall/CRC Press, and planned to appear as Chapter 4.4 with the title ‘Parametric methods'.) 1 Introduction This chapter considers...... inference procedures for parametric spatial point process models. The widespread use of sensible but ad hoc methods based on summary statistics of the kind studied in Chapter 4.3 have through the last two decades been supplied by likelihood based methods for parametric spatial point process models....... The increasing development of such likelihood based methods, whether frequentist or Bayesian, has lead to more objective and efficient statistical procedures. When checking a fitted parametric point process model, summary statistics and residual analysis (Chapter 4.5) play an important role in combination...

  11. 矿用避难硐室环境综合监测与通讯传输系统设计%The Design of Mine Escape Capsule Environmental Monitoring and Communication System

    Institute of Scientific and Technical Information of China (English)

    刘文强; 颜静; 郭斌

    2012-01-01

    该文设计了一种新型矿用避难硐室环境综合监测和通讯系统的设计方案。避难硐室是矿井发生矿难时重要的井下紧急避险设施,能为无法撤离的人员提供生命保障。避难硐室的环境监测系统是避难人员在密闭空间内生存依靠的重要保障,它包括硐室内外气体参数(至少CO、CO2、O2、CH4四种)、温湿度等人员生存的必需条件的实时监测。采用LPCI766为核心器件,与非色散红外气体传感器、电化学气体传感器、信号调理、MD模数转换等模块相结合,组成环境参数信号的采集系统,通过RS485通信方式与外部系统进行数据通信,通过现场测试证明,这种方法是完全可行的。%This paper designed a new design scheme of mine asylum cavern environment comprehensive monitoring and the communication systemAsylum cavern is an important underground emergency facili- ties when mining accident happens in the mine,and can provide life security for the people who can't e- vacuate.The environment monitoring system of Asylum cavern is the important guarantee that the refuge personnel in an airtight room in survival depends on,including indoor and outdoor gas safety parameters(at least in CO and CO2, O2, CH4 four),temperature and humidity etc real-time monitoring to assure the vital conditions of the personnel survival.Taking the LPC1766 for the core device,which combines infrared gas sensors,electrochemical gas sensors,signal disposal and A/D conversion module into environmental pa- rameters of signal collection system,and RS485 communication mode is used for data communication.

  12. Parametric Transverse Patterns in Broad Aperture Lasers

    DEFF Research Database (Denmark)

    Grigorieva, E.V.; Kashchenko, S.A.; Mosekilde, Erik

    1998-01-01

    Parametrically generated optical patterns are investigated for finite and large-scale transverse aperture lasers. Standing and rotating patterns as well as periodic and chaotic pattern alternations are described in the framework of the amplitude equation formalism. Sensitive dependence on the geo......Parametrically generated optical patterns are investigated for finite and large-scale transverse aperture lasers. Standing and rotating patterns as well as periodic and chaotic pattern alternations are described in the framework of the amplitude equation formalism. Sensitive dependence...

  13. Parametric resonance in concrete beam-columns

    OpenAIRE

    Sharma,Mamta R.; Singh,Arbind K; Benipal,Gurmail S

    2014-01-01

    A dynamic instability, called parametric resonance, is exhibited by undampedelastic beam-columns when under the action of pulsating axial force. The scope of the existing theory of parametric resonance is restricted to physically linear beam-columns undergoing finite lateral displacements. In this Paper, the dynamic behaviour of physically nonlinear elastic cracked concrete beam-columns under pulsating axial force and constant lateral force is investigated. The constitutive equations derived ...

  14. Narrow linewidth pulsed optical parametric oscillator

    Indian Academy of Sciences (India)

    S Das

    2010-11-01

    Tunable narrow linewidth radiation by optical parametric oscillation has many applications, particularly in spectroscopic investigation. In this paper, different techniques such as injection seeding, use of spectral selecting element like grating, grating and etalon in combination, grazing angle of incidence, entangled cavity configuration and type-II phase matching have been discussed for generating tunable narrow linewidth radiation by singly resonant optical parametric oscillation process.

  15. Chaos control of parametric driven Duffing oscillators

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Leisheng; Mei, Jie; Li, Lijie, E-mail: L.Li@swansea.ac.uk [College of Engineering, Swansea University, Swansea SA2 8PP (United Kingdom)

    2014-03-31

    Duffing resonators are typical dynamic systems, which can exhibit chaotic oscillations, subject to certain driving conditions. Chaotic oscillations of resonating systems with negative and positive spring constants are identified to investigate in this paper. Parametric driver imposed on these two systems affects nonlinear behaviours, which has been theoretically analyzed with regard to variation of driving parameters (frequency, amplitude). Systematic calculations have been performed for these two systems driven by parametric pumps to unveil the controllability of chaos.

  16. Chaos control of parametric driven Duffing oscillators

    Science.gov (United States)

    Jin, Leisheng; Mei, Jie; Li, Lijie

    2014-03-01

    Duffing resonators are typical dynamic systems, which can exhibit chaotic oscillations, subject to certain driving conditions. Chaotic oscillations of resonating systems with negative and positive spring constants are identified to investigate in this paper. Parametric driver imposed on these two systems affects nonlinear behaviours, which has been theoretically analyzed with regard to variation of driving parameters (frequency, amplitude). Systematic calculations have been performed for these two systems driven by parametric pumps to unveil the controllability of chaos.

  17. Summary of the U.S. specimen matrix for the HFIR 13J varying temperature irradiation capsule

    Energy Technology Data Exchange (ETDEWEB)

    Zinkle, S.J. [Oak Ridge National Lab., TN (United States)

    1998-03-01

    The US specimen matrix for the collaborative DOE/Monbusho HFIR 13J varying temperature irradiation capsule contains two ceramics and 29 different metals, including vanadium alloys, ferritic/martensitic steels, pure iron, austenitic stainless steels, nickel alloys, and copper alloys. This experiment is designed to provide fundamental information on the effects of brief low-temperature excursions on the tensile properties and microstructural evolution of a wide range of materials irradiated at nominal temperatures of 350 and 500 C to a dose of {approximately}5 dpa. A total of 340 miniature sheet tensile specimens and 274 TEM disks are included in the US-supplied matrix for the irradiation capsule.

  18. Parametric modelling and optimization of building structures with Rhinoceros-Grasshopper

    OpenAIRE

    Soklič, Rok

    2015-01-01

    This graduation thesis comprises the use of modern geometry design software in the process of structural design. By implementing parametrically designed geometry and interactively linking 3D computer graphics application software with structural analysis software, tasks involved in structural design (e.g. automatic design data transfer) can be significantly improved. In the first part of the thesis, the basics of NURBS (Non-uniform Rational Basis Spline) mathematical elements are briefly pres...

  19. In-to-out body path loss for wireless radio frequency capsule endoscopy in a human body.

    Science.gov (United States)

    Vermeeren, G; Tanghe, E; Thielens, A; Martens, L; Joseph, W; Vermeeren, G; Tanghe, E; Thielens, A; Martens, L; Joseph, W; Tanghe, E; Thielens, A; Martens, L; Vermeeren, G; Joseph, W

    2016-08-01

    Physical-layer characterization is important for design of in-to-out body communication for wireless body area networks (WBANs). This paper numerically investigates the path loss of an in-to-out body radio frequency (RF) wireless link between an endoscopy capsule and a receiver outside the body using a 3D electromagnetic solver. A spiral antenna in the endoscopy capsule is tuned to operate in the Medical Implant Communication Service (MICS) band at 402 MHz, accounting for the properties of the human body. The influence of misalignment, rotation of the capsule, and human body model are investigated. Semi-empirical path loss models for various homogeneous tissues and 3D realistic human body models are provided for manufacturers to evaluate the performance of in-to-out-body WBAN systems.

  20. RAMA Surveillance Capsule and Component Activation Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Watkins, Kenneth E.; Jones, Eric N. [TransWare Enterprises Inc., 1565 Mediterranean Dr., Sycamore, IL 60178 (United States); Carter, Robert G. [Electric Power Research Institute, 1300 West W. T. Harris Blvd., Charlotte, NC 28262 (United States)

    2011-07-01

    This paper presents the calculated-to-measured ratios associated with the application of the RAMA Fluence Methodology software to light water reactor surveillance capsule and reactor component activation evaluations. Comparisons to measurements are performed for pressurized water reactor and boiling water reactor surveillance capsule activity specimens from seventeen operating light water reactors. Comparisons to measurements are also performed for samples removed from the core shroud, top guide, and jet pump brace pads from two reactors. In conclusion: The flexible geometry modeling capabilities provided by RAMA, combined with the detailed representation of operating reactor history and anisotropic scattering detail, produces accurate predictions of the fast neutron fluence and neutron activation for BWR and PWR surveillance capsule geometries. This allows best estimate RPV fluence to be determined without the need for multiplicative bias corrections. The three-dimensional modeling capability in RAMA provides an accurate estimate of the fast neutron fluence for regions far removed from the core mid-plane elevation. The comparisons to activation measurements for various core components indicate that the RAMA predictions are reasonable, and notably conservative (i.e., C/M ratios are consistently greater than unity). It should be noted that in the current evaluations, the top and bottom fuel regions are represented by six inch height nodes. As a result, the leakage-induced decrease in power near the upper and lower edges of the core are not well represented in the current models. More precise predictions of fluence for components that lie above and below the core boundaries could be obtained if the upper and lower fuel nodes were subdivided into multiple axial regions with assigned powers that reflect the neutron leakage at the top and bottom of the core. This use of additional axial sub-meshing at the top and bottom of the core is analogous to the use of pin

  1. Efficient Characterization of Parametric Uncertainty of Complex (Biochemical Networks.

    Directory of Open Access Journals (Sweden)

    Claudia Schillings

    2015-08-01

    Full Text Available Parametric uncertainty is a particularly challenging and relevant aspect of systems analysis in domains such as systems biology where, both for inference and for assessing prediction uncertainties, it is essential to characterize the system behavior globally in the parameter space. However, current methods based on local approximations or on Monte-Carlo sampling cope only insufficiently with high-dimensional parameter spaces associated with complex network models. Here, we propose an alternative deterministic methodology that relies on sparse polynomial approximations. We propose a deterministic computational interpolation scheme which identifies most significant expansion coefficients adaptively. We present its performance in kinetic model equations from computational systems biology with several hundred parameters and state variables, leading to numerical approximations of the parametric solution on the entire parameter space. The scheme is based on adaptive Smolyak interpolation of the parametric solution at judiciously and adaptively chosen points in parameter space. As Monte-Carlo sampling, it is "non-intrusive" and well-suited for massively parallel implementation, but affords higher convergence rates. This opens up new avenues for large-scale dynamic network analysis by enabling scaling for many applications, including parameter estimation, uncertainty quantification, and systems design.

  2. Estimates of power deposited via cesium/barium beta and gamma radiation captured in components of a Hanford cesium chloride capsule and by components of overpacked capsules placed in an interim dry storage facility

    Energy Technology Data Exchange (ETDEWEB)

    Roetman, V.E., Westinghouse Hanford

    1996-12-23

    The deposition of power in Hanford cesium chloride capsules and in the components of design concepts for overpacking and interim storage were determined as requested (Randklev, 1996a). The power deposition results from the selective capture of gamma and beta radiation coming from the decay of the 137CS isotope in the CsCl contained in the capsules. The following three cases were analyzed: (a) a single CsCl capsule, (b) an overpack containing eight CsCl capsules, and (c) an infinite square array of such overpacks as placed in tubes of a interim dry storage facility. The power deposition was expressed as watts per gram for each of the respective physical design components in these three cases. Per the analyses request and guidance (Randklev 1996a), the primary analysis objective was to characterize, for each case, the power deposition across the radial cross-section at the expected axial position of maximum deposition. As requested, this primary part of the analysis work was done using choices for component dimension and material properties that would reasonably characterize the maximum deposition profile across the salt (CsCl) and the inner capsule barrier of the double walled metal capsule system used to construct the Hanford capsules. The secondary objective was to further evaluate the deposition behavior relative to the influence of axial position. The guidance (Randklev 1996a) also requested 1797 an analysis case that involved a lag-storage pit in a hot-cell, in which a cylindrical metal basket from a transportation cask would be used to position several capsules in the lag-storage pit. Although the basic model for the lag storage concept evaluation was essentially completed by the end of FY-96, the analysis was not run because of the need to prioritize and limit the work scope due to funding limitations for FY-97. The specific purpose for performing the subject set of analyses (Randklev 1996a) is to obtain power deposition values (i.e., per the decay of T37cs

  3. A comparative study on liquid core formulation on the diameter on the alginate capsules

    Science.gov (United States)

    Ong, Hui-Yen; Lee, Boon-Beng; Radzi, AkmalHadi Ma'; Zakaria, Zarina; Chan, Eng-Seng

    2015-08-01

    Liquid core capsule has vast application in biotechnology related industries such as pharmaceutical, medical, agriculture and food. Formulation of different types of capsule was important to determine the performance of the capsule. Generally, the liquid core capsule with different formulations generated different size of capsule.Therefore, the aim of this project is to investigate the effect of different liquid core solution formulations on the diameter of capsule. The capsule produced by extruding liquid core solutions into sodium alginate solution. Three types of liquid core solutions (chitosan, xanthan gum, polyethylene glycol (PEG)) were investigated. The results showed that there is significant change in capsule diameter despite in different types of liquid core solution were used and a series of capsule range in diameter of 3.1 mm to 4.5 mm were produced. Alginate capsule with chitosan formulation appeared to be the largest capsule among all.

  4. Ultra-Broad-Band Optical Parametric Amplifier or Oscillator

    Science.gov (United States)

    Strekalov, Dmitry; Matsko, Andrey; Savchenkov, Anatolly; Maleki, Lute

    2009-01-01

    A concept for an ultra-broad-band optical parametric amplifier or oscillator has emerged as a by-product of a theoretical study in fundamental quantum optics. The study was originally intended to address the question of whether the two-photon temporal correlation function of light [in particular, light produced by spontaneous parametric down conversion (SPDC)] can be considerably narrower than the inverse of the spectral width (bandwidth) of the light. The answer to the question was found to be negative. More specifically, on the basis of the universal integral relations between the quantum two-photon temporal correlation and the classical spectrum of light, it was found that the lower limit of two-photon correlation time is set approximately by the inverse of the bandwidth. The mathematical solution for the minimum two-photon correlation time also provides the minimum relative frequency dispersion of the down-converted light components; in turn, the minimum relative frequency dispersion translates to the maximum bandwidth, which is important for the design of an ultra-broad-band optical parametric oscillator or amplifier. In the study, results of an analysis of the general integral relations were applied in the case of an optically nonlinear, frequency-dispersive crystal in which SPDC produces collinear photons. Equations were found for the crystal orientation and pump wavelength, specific for each parametric-down-converting crystal, that eliminate the relative frequency dispersion of collinear degenerate (equal-frequency) signal and idler components up to the fourth order in the frequency-detuning parameter

  5. Optimal Bowel Preparation for Video Capsule Endoscopy

    Directory of Open Access Journals (Sweden)

    Hyun Joo Song

    2016-01-01

    Full Text Available During video capsule endoscopy (VCE, several factors, such as air bubbles, food material in the small bowel, and delayed gastric and small bowel transit time, influence diagnostic yield, small bowel visualization quality, and cecal completion rate. Therefore, bowel preparation before VCE is as essential as bowel preparation before colonoscopy. To date, there have been many comparative studies, consensus, and guidelines regarding different kinds of bowel cleansing agents in bowel preparation for small bowel VCE. Presently, polyethylene glycol- (PEG- based regimens are given primary recommendation. Sodium picosulphate-based regimens are secondarily recommended, as their cleansing efficacy is less than that of PEG-based regimens. Sodium phosphate as well as complementary simethicone and prokinetics use are considered. In this paper, we reviewed previous studies regarding bowel preparation for small bowel VCE and suggested optimal bowel preparation of VCE.

  6. Obscure gastrointestinal bleeding: difficulties in comparing CT enterography and video capsule endoscopy

    Energy Technology Data Exchange (ETDEWEB)

    Soyer, Philippe [Hopital Lariboisiere-APHP 2, Department of Imaging and Nuclear Medicine, Paris (France); UMR INSERM 965-Paris 7 ' ' Angiogenese et recherche translationnelle' ' , Paris (France); Universite Diderot-Paris 7, Paris (France)

    2012-06-15

    A paper reports the results of a retrospective study that was designed to evaluate the potential role of video capsule endoscopy (VCE) in elucidating the cause of bleeding in patients with obscure gastrointestinal bleeding (OGIB) for whom CT enterography was negative. The authors highlight the limitations of dual-phase CT enterography for the detection of flat lesions of the small bowel such as ulcers, angiodysplasias or arteriovenous malformations, and confirm the superiority of VCE for the detection of this category of lesions. This commentary discusses some of the issues raised. Key Points circle Video capsule endoscopy surpasses CT enterography in detecting flat small bowel lesions. circle Retrospective VCE and CT enterography findings in obscure bleeding need further evaluation. circle A fair and unbiased comparison of the two investigations is still needed. (orig.)

  7. Hierarchically functionalized magnetic core/multishell particles and their postsynthetic conversion to polymer capsules.

    Science.gov (United States)

    Schmitt, Sophia; Silvestre, Martin; Tsotsalas, Manuel; Winkler, Anna-Lena; Shahnas, Artak; Grosjean, Sylvain; Laye, Fabrice; Gliemann, Hartmut; Lahann, Joerg; Bräse, Stefan; Franzreb, Matthias; Wöll, Christof

    2015-01-01

    The controlled synthesis of hierarchically functionalized core/multishell particles is highly desirable for applications in medicine, catalysis, and separation. Here, we describe the synthesis of hierarchically structured metal-organic framework multishells around magnetic core particles (magMOFs) via layer-by-layer (LbL) synthesis. The LbL deposition enables the design of multishell systems, where each MOF shell can be modified to install different functions. Here, we used this approach to create controlled release capsules, in which the inner shell serves as a reservoir and the outer shell serves as a membrane after postsynthetic conversion of the MOF structure to a polymer network. These capsules enable the controlled release of loaded dye molecules, depending on the surrounding media.

  8. Localization of a Robotic Capsule for GI Motility Inspection with a Portable Ultrasonic System

    Institute of Scientific and Technical Information of China (English)

    姜萍萍; 颜国正

    2004-01-01

    The micro-systems used for in vivo physical inspection have many advantages over traditional methods. In order to aid diagnosis of gastrointestinal (GI) motility disorders, a capsule is developed for GI pressure and pH inspection. Localization of the capsule in GI tract with time is a necessary condition for subsequent data analysis and medical diagnosis. It is also a common problem facing all in vivo mobile micro-systems. An approach of segment localization by utilizing some key points along GI tract is proposed. A portable ultrasonic detecting device was designed for this purpose. Experiments under conditions similar to GI tract were carried out and the results proved the effectiveness and reliability of this method and the device.

  9. Probing the Physics of Burning DT Capsules Using Gamma-ray Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Hayes-Sterbenz, Anna Catherine [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hale, Gerald M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Jungman, Gerard [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Paris, Mark W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-02-01

    The Gamma Reaction History (GRH) diagnostic developed and lead by the Los Alamos National Laboratory GRH Team is used to determine the bang time and burn width of imploded inertial confinement fusion capsules at the National Ignition Facility. The GRH team is conceptualizing and designing a new Gamma-­to-Electron Magnetic Spectrometer (GEMS), that would be capable of an energy resolution ΔE/E~3-­5%. In this whitepaper we examine the physics that could be explored by the combination of these two gamma-ray diagnostics, with an emphasis on the sensitivity needed for measurements. The main areas that we consider are hydrodynamical mixing, ablator areal density and density profile, and temporal variations of the density of the cold fuel and the ablator during the DT burn of the capsule.

  10. Reaction-in-Flight Neutrons as a Signature for Shell Mixing in NIF capsules

    CERN Document Server

    Hayes, A C; Grim, G P; Jungman, Gerard; Wilhelmy, J B

    2009-01-01

    We present analytic calculations and results from computational simulations showing that reaction-in-flight (RIF) neutrons act as a robust indicator for mixing of the ablator shell material into the fuel in DT capsules designed for the National Ignition Facility. The sensitivity of RIF neutrons to hydrodynamical mixing arises through the dependence of RIF production on charged-particle stopping lengths in the mixture of DT fuel and ablator material. Since the stopping power in the plasma is a sensitive function of the electron temperature and density, it is also sensitive to mix. RIF production scales approximately inversely with the degree of mixing taking place, and the ratio of RIF to downscattered neutrons provides a measure of the mix fraction and/or the mixing length. For sufficiently high-yield capsules, where spatially resolved RIF images may be possible, neutron imaging could be used to map RIF images into detailed mix images.

  11. Conceptual shape optimization of entry vehicles applied to capsules and winged fuselage vehicles

    CERN Document Server

    Dirkx, Dominic

    2017-01-01

    This book covers the parameterization of entry capsules, including Apollo capsules and planetary probes, and winged entry vehicles such as the Space Shuttle and lifting bodies. The aerodynamic modelling is based on a variety of panel methods that take shadowing into account, and it has been validated with flight and wind tunnel data of Apollo and the Space Shuttle. The shape optimization is combined with constrained trajectory analysis, and the multi-objective approach provides the engineer with a Pareto front of optimal shapes. The method detailed in Conceptual Shape Optimization of Entry Vehicles is straightforward, and the output gives the engineer insight in the effect of shape variations on trajectory performance. All applied models and algorithms used are explained in detail, allowing for reconstructing the design tool to the researcher’s requirements. Conceptual Shape Optimization of Entry Vehicles will be of interest to both researchers and graduate students in the field of aerospace engineering, an...

  12. [Tri-dimensional omics analysis on effect of zhuanggu zhitong capsule against experimental postmenopausal osteoporosis].

    Science.gov (United States)

    Li, Jin-Ping; Zeng, Ying; Lei, Xiao-Ming; Zhang, Guo-Min; Liu, Hui-Ping; Mo, Xin-Min

    2014-08-01

    To propose the new concept of multidimensional omics, and define that the multidimensional omics is a proper method for studying the material base and mechanism of traditional Chinese medicine (TCM) compounds. Zhuanggu Zhitong capsule was taken for example to study its effect against experimental postmenopausal osteoporosis. From the perspective of chemi-omics, genomics and proteomics of TCM, it systematically interpreted the efficacious materials and mechanisms of Zhuanggu Zhitong capsule in preventing and treating experimental postmenopausal osteoporosis, while taking the lead in designing a three dimensional form to intuitively exhibit the results of the multidimensional omics study. This study provides a new idea and solution for studies on the efficacious materials and mechanisms of TCM compounds.

  13. In vitro study on sustained release capsule formulation of acetazolamide.

    Science.gov (United States)

    Pandey, V P; Kannan, K; Manavalan, R; Desai, N

    2003-10-01

    In the present study formulation of sustained release capsule of acetazolamide 250 mg was tried using nonpareil seeds. Nonpareil seeds were coated with drug, polyvinylpyrrolidone, glyceryl monostearate, microcrystalline wax, and glyceryl distearate either individually or in combination to achieve sustained release capsule 250 mg. In successful formulation 20% drug coated pellets and 80% wax coated pellets were taken. Wax coated pellets for successful formulation contained coating of microcrystalline wax and glyceryl distearate on drug coated pellets of the same concentration of 1.6% w/w. Successful formulated sustained release capsule 250 mg of acetazolamide was compared in in vitro study with theoretical sustained release formulation suggested by wagner and one marketed sustained release capsule 250 mg. Formulated capsule showed result superior to or on par with marketed capsule. For successful formulation pellets were filled in '1' size hard gelatin capsule and stability study was carried out in hot air over at room temperature and 45 degrees C for 5 weeks. The formulation was found stable in respect of drug content and release rate.

  14. Solid State Stability of Extemporaneously Prepared Levothyroxine Aliquots and Capsules.

    Science.gov (United States)

    Fortner, Jeff; Salton, Jason; Carlson, Christie; Wheeler, Rich; Cote, Brianna; Rao, Deepa

    2015-01-01

    The purpose of this research was to collect, analyze, and compare stability data for levothyroxine (T4) powder in the anhydrous and pentahydrate form when prepared as an aliquot and in capsules. Two different compounding pharmacies, Central Iowa Compounding and Gateway Medical Pharmacy, used different forms of T4 and aliquot formulations, which were studied to determine the beyond-use date at ±5% or ±10% of labeled strength. T4 was extracted from aliquot and capsule formulations and assessed using reverse-phase high- performance liquid chromatography validated to differentiate between the degraded and original forms of T4. The results indicate that T4 1:100 aliquot formulation prepared with silica gel or Avicel as filler are stable for 120 days at ±10% labeled potency, but at ±5% labeled potency, the silica gel and Avicel aliquot formulations are stable for 45 and 30 days, respectively. The silica gel capsules prepared from fresh aliquot were stable for 120 days at ±10% labeled potency and 90 days at ±5% labeled potency, while the Avicel capsules prepared from fresh aliquot were stable for 180 days at both ±10% and ±5% labeled potency. Avicel capsules prepared from old aliquot (120 days) and fresh aliquot (1 day) were also compared for stability. The old aliquot Avicel capsules were stable for 14 days at ±5% labeled potency and 150 days at ±10% labeled potency, while new aliquot Avicel capsules were stable for 180 days at both ±10% and ±5% labeled potency. Based on our data, there can be significant variation in the beyond-use dates assigned to T4 capsules based on the diluents used for aliquots, the final capsule formulations, and the potency standards applied. These results also indicate that pharmacists must exercise caution when using older aliquots and may have to assign shorter beyond-use dates.

  15. Tethered capsule OCT endomicroscopy for upper gastrointestinal tract imaging by using ball lens probe (Conference Presentation)

    Science.gov (United States)

    Dong, Jing; Gora, Michalina J.; Reddy, Rohith; Trasischker, Wolfgang; Poupart, Oriane; Lu, Weina; Carruth, Robert W.; Grant, Catriona N.; Soomro, Amna R.; Tiernan, Aubrey R.; Rosenberg, Mireille; Nishioka, Norman S.; Tearney, Guillermo J.

    2016-03-01

    While endoscopy is the most commonly used modality for diagnosing upper GI tract disease, this procedure usually requires patient sedation that increases cost and mandates its operation in specialized settings. In addition, endoscopy only visualizes tissue superfically at the macroscopic scale, which is problematic for many diseases that manifest below the surface at a microscopic scale. Our lab has previously developed technology termed tethered capsule OCT endomicroscopy (TCE) to overcome these diagnostic limitations of endoscopy. The TCE device is a swallowable capsule that contains optomechanical components that circumferentially scan the OCT beam inside the body as the pill traverses the organ via peristalsis. While we have successfully imaged ~100 patients with the TCE device, the optics of our current device have many elements and are complex, comprising a glass ferrule, optical fiber, glass spacer, GRIN lens and prism. As we scale up manufacturing of this device for clinical translation, we must decrease the cost and improve the manufacturability of the capsule's optical configuration. In this abstract, we report on the design and development of simplificed TCE optics that replace the GRIN lens-based configuration with an angle-polished ball lens design. The new optics include a single mode optical fiber, a glass spacer and an angle polished ball lens, that are all fusion spliced together. The ball lens capsule has resolutions that are comparable with those of our previous GRIN lens configuration (30µm (lateral) × 7 µm (axial)). Results in human subjects show that OCT-based TCE using the ball lens not only provides rapid, high quality microstructural images of upper GI tract, but also makes it possible to implement this technology inexpensively and on a larger scale.

  16. Comparison of reliability techniques of parametric and non-parametric method

    Directory of Open Access Journals (Sweden)

    C. Kalaiselvan

    2016-06-01

    Full Text Available Reliability of a product or system is the probability that the product performs adequately its intended function for the stated period of time under stated operating conditions. It is function of time. The most widely used nano ceramic capacitor C0G and X7R is used in this reliability study to generate the Time-to failure (TTF data. The time to failure data are identified by Accelerated Life Test (ALT and Highly Accelerated Life Testing (HALT. The test is conducted at high stress level to generate more failure rate within the short interval of time. The reliability method used to convert accelerated to actual condition is Parametric method and Non-Parametric method. In this paper, comparative study has been done for Parametric and Non-Parametric methods to identify the failure data. The Weibull distribution is identified for parametric method; Kaplan–Meier and Simple Actuarial Method are identified for non-parametric method. The time taken to identify the mean time to failure (MTTF in accelerating condition is the same for parametric and non-parametric method with relative deviation.

  17. Researches on Magnetic Localization for Detecting Capsule in Gastrointestinal Tract

    Institute of Scientific and Technical Information of China (English)

    HE Wen-hui; YAN Guo-zheng; GUO Xu-dong; WANG Kun-dong

    2007-01-01

    Recently, the capsule detection for examination of gastrointestinal (GI) tract became a novel noninvasive system, but it was still a problem for capsule's location.This paper examined various technologies used for measuring position based on magnetic method of the capsule in GI tract, while some new methods were investigated and their efficiency and complexity were analyzed.The results show that the radio frequency location is only practicable, but the tri-coil stimulating magnetic method and magnetic marker method can help to acquire a high precise, simplified, efficient and localized device.

  18. Characterisation of two AGATA asymmetric high purity germanium capsules

    Energy Technology Data Exchange (ETDEWEB)

    Colosimo, S.J., E-mail: sjc@ns.ph.liv.ac.uk [Department of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Moon, S.; Boston, A.J.; Boston, H.C.; Cresswell, J.R.; Harkness-Brennan, L.; Judson, D.S. [Department of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Lazarus, I.H. [STFC Daresbury, Daresbury, Warrington WA4 4AD (United Kingdom); Nolan, P.J. [Department of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Simpson, J. [STFC Daresbury, Daresbury, Warrington WA4 4AD (United Kingdom); Unsworth, C. [Department of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE (United Kingdom)

    2015-02-11

    The AGATA spectrometer is an array of highly segmented high purity germanium detectors. The spectrometer uses pulse shape analysis in order to track Compton scattered γ-rays to increase the efficiency of nuclear spectroscopy studies. The characterisation of two high purity germanium detector capsules for AGATA of the same A-type has been performed at the University of Liverpool. This work will examine the uniformity of performance of the two capsules, including a comparison of the resolution and efficiency as well as a study of charge collection. The performance of the capsules shows good agreement, which is essential for the efficient operation of the γ-ray tracking array.

  19. Parametric Optimization of Biomass Steam-and-Gas Plant

    Directory of Open Access Journals (Sweden)

    V. Sednin

    2013-01-01

    Full Text Available The paper contains a parametric analysis of the simplest scheme of a steam-and gas plant for the conditions required for biomass burning. It has been shown that application of gas-turbine and steam-and-gas plants can significantly exceed an efficiency of steam-power supply units which are used at the present moment. Optimum thermo-dynamical conditions for application of steam-and gas plants with the purpose to burn biomass require new technological solutions in the field of heat-exchange equipment designs.

  20. Parametric System Model for a Stirling Radioisotope Generator

    Science.gov (United States)

    Schmitz, Paul C.

    2015-01-01

    A Parametric System Model (PSM) was created in order to explore conceptual designs, the impact of component changes and power level on the performance of the Stirling Radioisotope Generator (SRG). Using the General Purpose Heat Source (GPHS approximately 250 Wth) modules as the thermal building block from which a SRG is conceptualized, trade studies are performed to understand the importance of individual component scaling on isotope usage. Mathematical relationships based on heat and power throughput, temperature, mass, and volume were developed for each of the required subsystems. The PSM uses these relationships to perform component- and system-level trades.

  1. Externally pumped millimeter-wave Josephson-junction parametric amplifier

    DEFF Research Database (Denmark)

    Levinsen, M.T; Pedersen, Niels Falsig; Sørensen, Ole;

    1980-01-01

    A unified theory of the singly and doubly degenerate Josephson-junction parametric amplifier is presented. Experiments with single junctions on both amplifier modes at frequencies 10, 35, and 70 GHz are discussed. Low-noise temperature (∼100 K, single sideband (SSB)) and reasonable gain (∼8 d......B) were obtained at 35 GHz in the singly degenerate mode. On the basis of the theory and experiments, a general procedure for optimizing junction parameters is discussed and illustrated by the specific design of a 100-GHz amplifier....

  2. Strong environmental coupling in a Josephson parametric amplifier

    Energy Technology Data Exchange (ETDEWEB)

    Mutus, J. Y.; White, T. C.; Barends, R.; Chen, Yu; Chen, Z.; Chiaro, B.; Dunsworth, A.; Jeffrey, E.; Kelly, J.; Neill, C.; O' Malley, P. J. J.; Roushan, P.; Sank, D.; Vainsencher, A.; Wenner, J.; Cleland, A. N.; Martinis, John M., E-mail: martinis@physics.ucsb.edu [Department of Physics, University of California, Santa Barbara, California 93106-9530 (United States); Megrant, A. [Department of Physics, University of California, Santa Barbara, California 93106-9530 (United States); Department of Materials, University of California, Santa Barbara, California 93106 (United States); Sundqvist, K. M. [Department of Electrical and Computer Engineering, Texas A and M University, College Station, Texas 77843 (United States)

    2014-06-30

    We present a lumped-element Josephson parametric amplifier designed to operate with strong coupling to the environment. In this regime, we observe broadband frequency dependent amplification with multi-peaked gain profiles. We account for this behavior using the “pumpistor” model which allows for frequency dependent variation of the external impedance. Using this understanding, we demonstrate control over the complexity of gain profiles through added variation in the environment impedance at a given frequency. With strong coupling to a suitable external impedance, we observe a significant increase in dynamic range, and large amplification bandwidth up to 700 MHz giving near quantum-limited performance.

  3. Parametrization of PMNS matrix based on dodeca-symmetry

    CERN Document Server

    Kim, Jihn E

    2011-01-01

    The dodeca symmetry is designed to obtain the Cabibbo angle $\\theta_C^{\\rm CKM}$ approximately $15^{\\rm o}$ and the (11) element of $\\Vp$ as $\\cos 30^{\\rm o}$, leading to $\\theta_1^{\\rm PMNS}+\\theta_C^{\\rm CKM}\\simeq 45^{\\rm o}$. This leading order dodeca symmetric $\\Vp$ is corrected by small parameters, especially as an expansion in terms of a small parameter $\\beta$. Neglecting two Majorana phases, the expression of $\\Vp$ contains four parameters: a small $\\beta$, and three $\\Od(1)$ parameters $A,B,$ and $\\delta$. From the neutrino oscillation data, we present two parametrizations and estimate their $\\beta$'s.

  4. An explicit parametrization for casting constraints in gradient driven topology optimization

    DEFF Research Database (Denmark)

    Gersborg, Allan Roulund; Andreasen, Casper Schousboe

    From a practical point of view it is often desirable to limit the complexity of a topology design such that casting/milling type manufacturing techniques can be applied. In the context of gradient driven topology optimization this work studies how castable designs can be obtained by use of a Heav...... of a Heaviside design parametrization in a specific casint direction. This reduces the number of design variables considerably and the approach is simple to implement....

  5. 基于参数化设计的虚拟现实技术应用——厦门五缘湾“鹦鹉螺”音乐厅%The Application of Virtual Reality based on Parametric Design

    Institute of Scientific and Technical Information of China (English)

    孟卉; 何婷; 饶金通; 夏侯建兵

    2011-01-01

    随着计算机软件与硬件技术的高速发展,虚拟现实技术的应用越来越广泛。VRML是基于网络的三维语言,是Web3D的代表。本文通过在厦门五缘湾"鹦鹉螺"音乐厅的方案设计过程中,结合参数化设计方法和面向对象编程技术,应用VRML对建筑设计的虚拟现实可视化设计进行了实践,并证明该方法在建筑方案可视化决策中可以发挥巨大作用,大大提高了工程的设计效率和设计质量。%With the development of computer hardware and software, the Virtual Reality is applied more widely. VRML is the 3-Dimension language based on web, the representative of Web3D. In this arcticle, the VRML is applied in the design practice of Parrot-Conch Concert Hall ofXiamen Wuynan Gulf, through the Parametric Design and the Object-Orientation Programming. The application proved that VR has become the more and more important factor in the architectural visual design, and improved the efficiency and quality of desigu at the same time.

  6. Optical Parametric Amplification for High Peak and Average Power

    Energy Technology Data Exchange (ETDEWEB)

    Jovanovic, I

    2001-11-26

    Optical parametric amplification is an established broadband amplification technology based on a second-order nonlinear process of difference-frequency generation (DFG). When used in chirped pulse amplification (CPA), the technology has been termed optical parametric chirped pulse amplification (OPCPA). OPCPA holds a potential for producing unprecedented levels of peak and average power in optical pulses through its scalable ultrashort pulse amplification capability and the absence of quantum defect, respectively. The theory of three-wave parametric interactions is presented, followed by a description of the numerical model developed for nanosecond pulses. Spectral, temperature and angular characteristics of OPCPA are calculated, with an estimate of pulse contrast. An OPCPA system centered at 1054 nm, based on a commercial tabletop Q-switched pump laser, was developed as the front end for a large Nd-glass petawatt-class short-pulse laser. The system does not utilize electro-optic modulators or multi-pass amplification. The obtained overall 6% efficiency is the highest to date in OPCPA that uses a tabletop commercial pump laser. The first compression of pulses amplified in highly nondegenerate OPCPA is reported, with the obtained pulse width of 60 fs. This represents the shortest pulse to date produced in OPCPA. Optical parametric amplification in {beta}-barium borate was combined with laser amplification in Ti:sapphire to produce the first hybrid CPA system, with an overall conversion efficiency of 15%. Hybrid CPA combines the benefits of high gain in OPCPA with high conversion efficiency in Ti:sapphire to allow significant simplification of future tabletop multi-terawatt sources. Preliminary modeling of average power limits in OPCPA and pump laser design are presented, and an approach based on cascaded DFG is proposed to increase the average power beyond the single-crystal limit. Angular and beam quality effects in optical parametric amplification are modeled

  7. Design and Mechanics Simulation of Bionic Lubrication System of Artificial Joints

    Institute of Scientific and Technical Information of China (English)

    S. H. Su; Z. K. Hua; J. H. Zhang

    2006-01-01

    We propose a new structure for artificial joints with a joint capsule which is designed to overcome the drawback of current prostheses that omit many functions of the lubricant and the joint capsule. The new structure is composed of three components:lubricant, artificial joint and artificial joint capsule. The lubricant sealed in the capsule can not only reduce the wear of the artificial joint but also prevents the wear particles leaking into the body. So unexpected reactions between the wear particles and body can be avoided completely. A three-dimensional (3-D) finite element analysis (FEA) model was created for a bionic knee joint with capsule. The stresses and their distribution in the artificial capsule were simulated with different thickness, loadings,and flexion angles. The results show that the maximum stress occurs in the area between the artificial joint and the capsule. The effects of capsule thickness and the angles of flexion on stress are discussed in detail.

  8. Non-parametric partitioning of SAR images

    Science.gov (United States)

    Delyon, G.; Galland, F.; Réfrégier, Ph.

    2006-09-01

    We describe and analyse a generalization of a parametric segmentation technique adapted to Gamma distributed SAR images to a simple non parametric noise model. The partition is obtained by minimizing the stochastic complexity of a quantized version on Q levels of the SAR image and lead to a criterion without parameters to be tuned by the user. We analyse the reliability of the proposed approach on synthetic images. The quality of the obtained partition will be studied for different possible strategies. In particular, one will discuss the reliability of the proposed optimization procedure. Finally, we will precisely study the performance of the proposed approach in comparison with the statistical parametric technique adapted to Gamma noise. These studies will be led by analyzing the number of misclassified pixels, the standard Hausdorff distance and the number of estimated regions.

  9. Constructing parametric triangular patches with boundary conditions

    Institute of Scientific and Technical Information of China (English)

    Hui Liu; Jun Ma; Fuhua Cheng

    2008-01-01

    The problem of constructing a parametric triangular patch to smoothly connect three surface patches is studied. Usually, these surface patches are defined on different parameter spaces. Therefore, it is necessary to define interpolation conditions, with values from the given surface patches, on the boundary of the triangular patch that can ensure smooth transition between different parameter spaces. In this paper we present a new method to define boundary conditions. Boundary conditions defined by the new method have the same parameter space if the three given surface patches can be converted into the same form through affine transformation. Consequently, any of the classic methods for constructing functional triangular patches can be used directly to construct a parametric triangular patch to connect given surface patches with G continuity. The resulting parametric triangular patch preserves precision of the applied classic method.

  10. Modeling personnel turnover in the parametric organization

    Science.gov (United States)

    Dean, Edwin B.

    1991-01-01

    A model is developed for simulating the dynamics of a newly formed organization, credible during all phases of organizational development. The model development process is broken down into the activities of determining the tasks required for parametric cost analysis (PCA), determining the skills required for each PCA task, determining the skills available in the applicant marketplace, determining the structure of the model, implementing the model, and testing it. The model, parameterized by the likelihood of job function transition, has demonstrated by the capability to represent the transition of personnel across functional boundaries within a parametric organization using a linear dynamical system, and the ability to predict required staffing profiles to meet functional needs at the desired time. The model can be extended by revisions of the state and transition structure to provide refinements in functional definition for the parametric and extended organization.

  11. Minimization of Basis Risk in Parametric Earthquake Cat Bonds

    Science.gov (United States)

    Franco, G.

    2009-12-01

    second disfavors the investor who loses part of the investment without a reasonable cause. A streamlined and fairly automated methodology has been developed to design parametric triggers that minimize the basis risk while still maintaining their level of relative simplicity. Basis risk is minimized in both, first and second generation, parametric cat bonds through an optimization procedure that aims to find the most appropriate magnitude thresholds, geographic zones, and weight index values. Sensitivity analyses to different design assumptions show that first generation cat bonds are typically affected by a large negative basis risk, namely the risk that the bond will not trigger for events within the risk level transferred, unless a sufficiently small geographic resolution is selected to define the trigger zones. Second generation cat bonds in contrast display a bias towards negative or positive basis risk depending on the degree of the polynomial used as well as on other design parameters. Two examples are presented, the construction of a first generation parametric trigger mechanism for Costa Rica and the design of a second generation parametric index for Japan.

  12. Multiaxial mechanical behavior of the porcine anterior lens capsule.

    Science.gov (United States)

    Heistand, M R; Pedrigi, R M; Delange, S L; Dziezyc, J; Humphrey, J D

    2005-11-01

    The biomechanics of the lens capsule of the eye is important both in physiologic processes such as accommodation and clinical treatments such as cataract surgery. Although the lens capsule experiences multiaxial stresses in vivo, there have been no measurements of its multiaxial properties or possible regional heterogeneities. Rather all prior mechanical data have come from 1-D pressure-volume or uniaxial force-length tests. Here, we report a new experimental approach to study in situ the regional, multiaxial mechanical behavior of the lens capsule. Moreover, we report multiaxial data suggesting that the porcine anterior lens capsule exhibits a typical nonlinear pseudo-elastic behavior over finite strains, that the in situ state is pre-stressed multi-axially, and that the meridional and circumferential directions are principal directions of strain, which is nearly equi-biaxial at the pole but less so towards the equator. Such data are fundamental to much needed constitutive formulations.

  13. Capsule endoscopy of the future: What's on the horizon?

    Science.gov (United States)

    Slawinski, Piotr R; Obstein, Keith L; Valdastri, Pietro

    2015-10-01

    Capsule endoscopes have evolved from passively moving diagnostic devices to actively moving systems with potential therapeutic capability. In this review, we will discuss the state of the art, define the current shortcomings of capsule endoscopy, and address research areas that aim to overcome said shortcomings. Developments in capsule mobility schemes are emphasized in this text, with magnetic actuation being the most promising endeavor. Research groups are working to integrate sensor data and fuse it with robotic control to outperform today's standard invasive procedures, but in a less intrusive manner. With recent advances in areas such as mobility, drug delivery, and therapeutics, we foresee a translation of interventional capsule technology from the bench-top to the clinical setting within the next 10 years.

  14. [Acute caffeine intoxication after intake of 'herbal energy capsules'

    NARCIS (Netherlands)

    Kromhout, H.E.; Landstra, A.M.; Luin, M. van; Setten, P.A. van

    2008-01-01

    Two males, 15 and 17 years old respectively, presented at the Emergency Department complaining of cramping abdominal pain, nausea and vomiting after ingestion of energy capsules. Physical examination revealed sinus tachycardia and slight abdominal pain. Laboratory examination showed substantial hypo

  15. The mechanical properties of the human hip capsule ligaments.

    Science.gov (United States)

    Hewitt, John D; Glisson, Richard R; Guilak, Farshid; Vail, T Parker

    2002-01-01

    The human hip capsule is adapted to facilitate upright posture, joint stability, and ambulation, yet it routinely is excised in hip surgery without a full understanding of its mechanical contributions. The objective of this study was to provide information about the mechanical properties of the ligaments that form the hip capsule. Cadaver bone-ligament-bone specimens of the iliofemoral, ischiofemoral, and femoral arcuate ligaments were tested to failure in tension. The hip capsule was found to be an inhomogeneous structure and should be recognized as being composed of discrete constituent ligaments. The anterior ligaments, consisting of the 2 arms of the iliofemoral ligament, were much stronger than the posterior ischiofemoral ligament, withstanding greater force at failure and exhibiting greater stiffness. Knowledge of the anatomy and mechanical properties of the capsule may help the hip surgeon choose an appropriate surgical approach or repair strategy.

  16. Wireless capsule video endoscopy:Three years of experience

    Institute of Scientific and Technical Information of China (English)

    Rami Eliakim

    2004-01-01

    AIM: To review and summerize the current literatue regarding M2A wireless capsule endoscopy.METHODS: Peer reviewed publications regarding the use of capsule endoscopy as well as our personal experience were reviewed.RESULTS: Review of the literature dearly showed that capsule endoscopy was superior to enteroscopy, small bowel follow through and computerized tomography in patients with obscure gastrointestinal bleeding, iron deficiency anemia,or suspected Crohn′s disease. It was very sensitive for the diagnosis of small bowel tumors and for survailance of small bowel pathology in patients with Gardner syndrome or familial adenomatous polyposis syndrome. Its role in celiac disease and in patients with known Crohn′s disease was currently being investigated.CONCLUSION: Capsule video endoscopy is a superior and more sensitive diagnostic tool than barium follow through,enteroscopy and entero- CT in establishing the diagnosis of many small bowel pathologies.

  17. Perforation forces of the intact porcine anterior lens capsule.

    Science.gov (United States)

    Ullrich, Franziska; Lussi, Jonas; Felekis, Dimitrios; Michels, Stephan; Petruska, Andrew J; Nelson, Bradley J

    2016-09-01

    During the first step of cataract surgery, the lens capsule is perforated and a circular hole is created with a sharp instrument, a procedure called capsulorhexis. To develop automated systems that can assist ophthalmologists during capsulorhexis, the forces required must be quantified. This study investigates perforation forces of the central anterior lens capsule in porcine eyes, which are used as a conservative model for the human eye. A micro-mechanical characterisation method is presented that measures capsular bag perforation forces with a high precision positioning and high-resolution force sensing system. The force during perforation of the anterior lens capsule was measured with various sized needles and indentation speeds and is found to be 15-35mN. A bio-mechanical model is identified that describes an exponential correlation between indentation force and depth, indicating strain hardening behaviour of the porcine anterior lens capsule.

  18. Parametric adaptive estimation and backstepping control of electro-hydraulic actuator with decayed memory filter.

    Science.gov (United States)

    Guo, Qing; Sun, Ping; Yin, Jing-Min; Yu, Tian; Jiang, Dan

    2016-05-01

    Some unknown parameter estimation of electro-hydraulic system (EHS) should be considered in hydraulic controller design due to many parameter uncertainties in practice. In this study, a parametric adaptive backstepping control method is proposed to improve the dynamic behavior of EHS under parametric uncertainties and unknown disturbance (i.e., hydraulic parameters and external load). The unknown parameters of EHS model are estimated by the parametric adaptive estimation law. Then the recursive backstepping controller is designed by Lyapunov technique to realize the displacement control of EHS. To avoid explosion of virtual control in traditional backstepping, a decayed memory filter is presented to re-estimate the virtual control and the dynamic external load. The effectiveness of the proposed controller has been demonstrated by comparison with the controller without adaptive and filter estimation. The comparative experimental results in critical working conditions indicate the proposed approach can achieve better dynamic performance on the motion control of Two-DOF robotic arm.

  19. Plug and Play Robust Distributed Control with Ellipsoidal Parametric Uncertainty System

    Directory of Open Access Journals (Sweden)

    Hong Wang-jian

    2016-01-01

    Full Text Available We consider a continuous linear time invariant system with ellipsoidal parametric uncertainty structured into subsystems. Since the design of a local controller uses only information on a subsystem and its neighbours, we combine the plug and play idea and robust distributed control to propose one distributed control strategy for linear system with ellipsoidal parametric uncertainty. Firstly for linear system with ellipsoidal parametric uncertainty, a necessary and sufficient condition for robust state feedback control is proposed by means of linear matrix inequality. If this necessary and sufficient condition is satisfied, this robust state feedback gain matrix can be easily derived to guarantee robust stability and prescribed closed loop performance. Secondly the plug and play idea is introduced in the design process. Finally by one example of aircraft flutter model parameter identification, the efficiency of the proposed control strategy can be easily realized.

  20. Parametrization of the radiation induced leakage current increase of NMOS transistors

    CERN Document Server

    Backhaus, Malte

    2016-01-01

    The increase of the leakage current of NMOS transistors during exposure to ionizing radiation is known and well studied. Radiation hardness by design techniques have been developed to mitigate this effect and have been successfully used. More recent developments in smaller feature size technologies do not make use of these techniques due to their drawbacks in terms of logic density and requirement of dedicated libraries. During operation the resulting increase of the supply current is a serious challenge and needs to be considered during the system design. A simple parametrization of the leakage current of NMOS transistors as a function of total ionizing dose is presented. The parametrization uses a transistor transfer characteristics of the parasitic transistor along the shallow trench isolation to describe the leakage current of the nominal transistor. Together with a parametrization of the number of positive charges trapped in the silicon dioxide and number of activated interface traps in the silicon to si...

  1. Study of parametric instability in gravitational wave detectors with silicon test masses

    Science.gov (United States)

    Zhang, Jue; Zhao, Chunnong; Ju, Li; Blair, David

    2017-03-01

    Parametric instability is an intrinsic risk in high power laser interferometer gravitational wave detectors, in which the optical cavity modes interact with the acoustic modes of the mirrors, leading to exponential growth of the acoustic vibration. In this paper, we investigate the potential parametric instability for a proposed next generation gravitational wave detector, the LIGO Voyager blue design, with cooled silicon test masses of size 45 cm in diameter and 55 cm in thickness. It is shown that there would be about two unstable modes per test mass at an arm cavity power of 3 MW, with the highest parametric gain of  ∼76. While this is less than the predicted number of unstable modes for Advanced LIGO (∼40 modes with max gain of  ∼32 at the designed operating power of 830 kW), the importance of developing suitable instability suppression schemes is emphasized.

  2. Sensor-Aided Localized Capsule-Cooling Using Neural Networks for Energy-Efficient Refrigeration

    Directory of Open Access Journals (Sweden)

    N. Banerjee

    2014-06-01

    Full Text Available Sensor-aided localized capsule-cooling technique is a unique refrigeration process where sensors precisely capsulate the location of an item(s on a shelf of a fridge and hence direct the governing artificial intelligence to take suitable action. Here the sensors are used to locate the objects and the designed smart system (neural network activates the corresponding ductlines to cool the object. Here neural network system opens the gate(s and tilts the angle to allow the flow of cool air through the ductlines. Then the orifices, which fall in the virtual “Hot Region”, the domain that the active sensors had created almost immediately on sensing an obstruction, are opened. The orifices and sensors are arranged in a series on the lower wall of the ductlines to allow flow of air in the downward direction. These open orifices facilitate the direct hitting of cool air on the target-item and hence create a cold block within a fridge, instead of cooling the entire fridge uniformly, to keep the singular item refrigerated. This mode of operation offering selective cooling, rather than the conventional uniform one, is useful in saving energy, as the region then needed to be cooled is reduced significantly. A detail structural and theoretical explanations along with graphical analysis clearly elucidate the effective working of this mechanism under practical circumstances is given here. In this paper neural network is used for capsule cooling for energy efficient refrigeration

  3. First shock tuning and backscatter measurements for large case-to-capsule ratio beryllium targets

    Science.gov (United States)

    Loomis, Eric; Yi, Austin; Kline, John; Kyrala, George; Simakov, Andrei; Wilson, Doug; Ralph, Joe; Dewald, Eduard; Strozzi, David; Celliers, Peter; Millot, Marius; Tommasini, Riccardo

    2016-10-01

    The current under performance of target implosions on the National Ignition Facility (NIF) has necessitated scaling back from high convergence ratio to access regimes of reduced physics uncertainties. These regimes, we expect, are more predictable by existing radiation hydrodynamics codes giving us a better starting point for isolating key physics questions. One key question is the lack of predictable in-flight and hot spot shape due to a complex hohlraum radiation environment. To achieve more predictable, shape tunable implosions we have designed and fielded a large 4.2 case-to-capsule ratio (CCR) target at the NIF using 6.72 mm diameter Au hohlraums and 1.6 mm diameter Cu-doped Be capsules. Simulations show that at these dimensions during a 10 ns 3-shock laser pulse reaching 270 eV hohlraum temperatures, the interaction between hohlraum and capsule plasma, which at lower CCR lead to beam propagation impedance by artificial plasma stagnation, are reduced. In this talk we will present measurements of early time drive symmetry using two-axis line-imaging velocimetry (VISAR) and streaked radiography measuring velocity of the imploding shell and their comparisons to post-shot calculations using the code HYDRA (Lawrence Livermore National Laboratory).

  4. A batch fabricated capacitive pressure sensor with an integrated Guyton capsule for interstitial fluid pressure measurement

    Science.gov (United States)

    Maleki, Teimour; Fogle, Benjamin; Ziaie, Babak

    2011-05-01

    In this paper, we present the design, fabrication and test of a batch fabricated capacitive pressure sensor with an integrated Guyton capsule for interstitial fluid pressure measurement. The sensor is composed of 12 µm thick single crystalline silicon membrane and a 3 µm gap, hermetically sealed through silicon-glass anodic bonding. A novel batch scale method for creating electrical feed-throughs inside the sealed capacitor chamber is developed. The Guyton capsule consists of an array of 10 µm diameter access holes etched onto a silicon back-plate separated from the silicon sensing membrane by a gap of 5 µm. The presence of the Guyton capsule (i.e. plates with access holes plus the gap separating them from the sensing membrane) allows for the ingress of interstitial fluid inside the 5 µm gap following the implantation, thus, providing an accurate measurement of interstitial fluid pressure. The fabricated sensor is 3 × 2 × 0.42 mm3 in dimensions and has a maximum sensitivity of 10 fF mmHg-1.

  5. Catalytic oxygen production mediated by smart capsules to modulate elastic turbulence under a laminar flow regime.

    Science.gov (United States)

    Zizzari, A; Bianco, M; Miglietta, R; del Mercato, L L; Carraro, M; Sorarù, A; Bonchio, M; Gigli, G; Rinaldi, R; Viola, I; Arima, V

    2014-11-21

    Liquid flow in microchannels is completely laminar and uniaxial, with a very low Reynolds number regime and long mixing lengths. To increase fluid mixing and solubility of reactants, as well as to reduce reaction time, complex three-dimensional networks inducing chaotic advection have to be designed. Alternatively, turbulence in the liquid can be generated by active mixing methods (magnetic, acoustic waves, etc.) or adding small quantities of elastic materials to the working liquid. Here, polyelectrolyte multilayer capsules embodying a catalytic polyoxometalate complex have been suspended in an aqueous solution and used to create elastic turbulence and to propel fluids inside microchannels as an alternative to viscoelastic polymers. The overall effect is enhanced and controlled by feeding the polyoxometalate-modified capsules with hydrogen peroxide, H2O2, thus triggering an on-demand propulsion due to oxygen evolution resulting from H2O2 decomposition. The quantification of the process is done by analysing some structural parameters of motion such as speed, pressure, viscosity, and Reynolds and Weissenberg numbers, directly obtained from the capillary dynamics of the aqueous mixtures with different concentrations of H2O2. The increases in fluid speed as well as the capsule-induced turbulence effects are proportional to the H2O2 added and therefore dependent on the kinetics of H2O2 dismutation.

  6. Wireless power and data transmission strategies for next-generation capsule endoscopes

    Science.gov (United States)

    Puers, R.; Carta, R.; Thoné, J.

    2011-05-01

    Capsular endoscopy is becoming increasingly popular as an alternative to traditional gastro-intestinal (GI) examination techniques. However, the breakthrough of these devices is hindered by the limited amount of power that can be stored in a tiny pill. Most commercial devices use two watch batteries that can only provide an average power of 25 mW for about 6 h, certainly not sufficient for advanced robotic features. A dedicated inductive powering system, operating at 1 MHz to limit the human body absorption, has been developed which was proven to support the transfer of over 300 mW. The system relies on a condensed set of orthogonal ferrite coils, embedded in the capsule, and an external unit based on a Helmholtz coil driven by a class E amplifier. Control data can be sent through the inductive link by modulating the power carrier, whereas a dedicated high data rate RF link is used to transfer the images from the capsule to the base station. Besides evaluating the compatibility with radio transmission, several demonstrators were assembled combining the wireless powering system with various locomotion strategies and LED illumination. This paper describes the design and implementation of the inductive powering system, its combination with data transmission techniques and the testing activity with other capsule-dedicated modules.

  7. Research on Technology of Filling Sodium into Fuel Test Capsules

    Institute of Scientific and Technical Information of China (English)

    XU; Chi; XIE; Chun; WANG; Shu-xing; MI; Zheng-feng; YU; Tuan-jie; CUI; Chao; WANG; Ming-zheng

    2015-01-01

    In order to provide a high pure sodium environment for properties testing in the fuel research for fast reactor,it is essential to fill sodium into fuel testing capsules.By the method of vacuum,temperature-controlling and inert gas protection,quantificational sodium had been filled into the fuel testing capsules.Fig.1shows the schematic diagram of sodium filling device.Table 1shows

  8. Study of Contact Melting Inside Isothermally Heated Vertical Cylindrical Capsules

    Institute of Scientific and Technical Information of China (English)

    ChenWenzhen; ChengShangmo; 等

    1993-01-01

    Close-contact melting processes of phase change material(PCM) inside vertical cylindrical capsule are studied.PCM are heated bhy the capsule isothermalyy at the bottom and side.The theoretical formulas of the melting rate and thickness of liquid layer during the heat transfer process are obtained by analysis,which are convenient for engineering predictions.Finally,the factors that affect melting are discussed.and conclusions are drawn.

  9. Determining the Optimum Font Size for Braille on Capsule Paper

    OpenAIRE

    Watanabe, Tetsuya

    2014-01-01

    Braille fonts allow us to easily make braille labels on capsule paper. For legibility, fonts should be printed at optimum sizes. To find the optimum sizes for Japanese braille fonts, we conducted an experiment in which a Japanese braille font was printed at various sizes on capsule paper and read and rated by young braille users. The results show that braille printed at 17 and 18 point sizes were read faster and evaluated higher than those printed at smaller or bigger sizes.

  10. Parametric injection for monoenergetic electron acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Oguchi, A; Takano, K; Hotta, E; Nemoto, K [Department of Energy Sciences Tokyo Institute of Technology 4259 Nagatsuta-cho Midori-ku Yokohama 226-8502 Japan (Japan); Zhidkov, A [Central Research Instistute of Electric Power Industry 2-6-1 Nagasaka Yokosuka Kanagawa 240-0196 Japan (Japan); Nakajima, K [High Energy Accelerator Research Organization, KEK 1-1 Oho Tsukuba Ibaraki 305-0801 Japan (Japan)], E-mail: blue-ayu@plasma.es.titech.ac.jp

    2008-05-01

    Electrons are accelerated in the laser wakefield (LWFA). This mechanism has been studied by 2D or 3D Particle In Cell simulation. However, how the electrons are injected in the wakefield is not understood. In this paper, we consider about the process of self -injection and propose new scheme. When plasma electron density modulates, parametric resonance of electron momentum is induced. The parametric resonance depends on laser waist modulation. We carried out 2D PIC simulation with the initial condition decided from resonance condition. Moreover, we analyze experimental result that generated 200-250 MeV monoenergetic electron beam with 400TW intense laser in CAEP in China.

  11. Hamiltonian dynamics of the parametrized electromagnetic field

    CERN Document Server

    G., J Fernando Barbero; Villaseñor, Eduardo J S

    2015-01-01

    We study the Hamiltonian formulation for a parametrized electromagnetic field with the purpose of clarifying the interplay between parametrization and gauge symmetries. We use a geometric approach which is tailor-made for theories where embeddings are part of the dynamical variables. Our point of view is global and coordinate free. The most important result of the paper is the identification of sectors in the primary constraint submanifold in the phase space of the model where the number of independent components of the Hamiltonian vector fields that define the dynamics changes. This explains the non-trivial behavior of the system and some of its pathologies.

  12. The Stellar parametrization using Artificial Neural Network

    CERN Document Server

    Giridhar, Sunetra; Kunder, Andrea; Muneer, S; Kumar, G Selva

    2012-01-01

    An update on recent methods for automated stellar parametrization is given. We present preliminary results of the ongoing program for rapid parametrization of field stars using medium resolution spectra obtained using Vainu Bappu Telescope at VBO, Kavalur, India. We have used Artificial Neural Network for estimating temperature, gravity, metallicity and absolute magnitude of the field stars. The network for each parameter is trained independently using a large number of calibrating stars. The trained network is used for estimating atmospheric parameters of unexplored field stars.

  13. Hamiltonian dynamics of the parametrized electromagnetic field

    Science.gov (United States)

    Barbero G, J. Fernando; Margalef-Bentabol, Juan; Villaseñor, Eduardo J. S.

    2016-06-01

    We study the Hamiltonian formulation for a parametrized electromagnetic field with the purpose of clarifying the interplay between parametrization and gauge symmetries. We use a geometric approach which is tailor-made for theories where embeddings are part of the dynamical variables. Our point of view is global and coordinate free. The most important result of the paper is the identification of sectors in the primary constraint submanifold in the phase space of the model where the number of independent components of the Hamiltonian vector fields that define the dynamics changes. This explains the non-trivial behavior of the system and some of its pathologies.

  14. National Ignition Facility Target Design and Fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Cook, R C; Kozioziemski, B J; Nikroo, A; Wilkens, H L; Bhandarkar, S; Forsman, A C; Haan, S W; Hoppe, M L; Huang, H; Mapoles, E; Moody, J D; Sater, J D; Seugling, R M; Stephens, R B; Takagi, M; Xu, H W

    2007-12-10

    The current capsule target design for the first ignition experiments at the NIF Facility beginning in 2009 will be a copper-doped beryllium capsule, roughly 2 mm in diameter with 160-{micro}m walls. The capsule will have a 75-{micro}m layer of solid DT on the inside surface, and the capsule will driven with x-rays generated from a gold/uranium cocktail hohlraum. The design specifications are extremely rigorous, particularly with respect to interfaces, which must be very smooth to inhibit Rayleigh-Taylor instability growth. This paper outlines the current design, and focuses on the challenges and advances in capsule fabrication and characterization; hohlraum fabrication, and D-T layering and characterization.

  15. Pickering Emulsion-Based Marbles for Cellular Capsules

    Directory of Open Access Journals (Sweden)

    Guangzhao Zhang

    2016-07-01

    Full Text Available The biodegradable cellular capsule, being prepared from simple vaporization of liquid marbles, is an ideal vehicle for the potential application of drug encapsulation and release. This paper reports the fabrication of cellular capsules via facile vaporization of Pickering emulsion marbles in an ambient atmosphere. Stable Pickering emulsion (water in oil was prepared while utilizing dichloromethane (containing poly(l-lactic acid and partially hydrophobic silica particles as oil phase and stabilizing agents respectively. Then, the Pickering emulsion marbles were formed by dropping emulsion into a petri dish containing silica particles with a syringe followed by rolling. The cellular capsules were finally obtained after the complete vaporization of both oil and water phases. The technique of scanning electron microscope (SEM was employed to research the microstructure and surface morphology of the prepared capsules and the results showed the cellular structure as expected. An in vitro drug release test was implemented which showed a sustained release property of the prepared cellular capsules. In addition, the use of biodegradable poly(l-lactic acid and the biocompatible silica particles also made the fabricated cellular capsules of great potential in the application of sustained drug release.

  16. MALDI-MS-imaging of whole human lens capsule.

    Science.gov (United States)

    Ronci, Maurizio; Sharma, Shiwani; Chataway, Tim; Burdon, Kathryn P; Martin, Sarah; Craig, Jamie E; Voelcker, Nicolas H

    2011-08-05

    The ocular lens capsule is a smooth, transparent basement membrane that encapsulates the lens and is composed of a rigid network of interacting structural proteins and glycosaminoglycans. During cataract surgery, the anterior lens capsule is routinely removed in the form of a circular disk. We considered that the excised capsule could be easily prepared for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry imaging (MALDI-MSI) analysis. MALDI-MSI is a powerful tool to elucidate the spatial distribution of small molecules, peptides, and proteins within tissues. Here, we apply this molecular imaging technique to analyze the freshly excised human lens capsule en face. We demonstrate that novel information about the distribution of proteins by MALDI-MSI can be obtained from this highly compact connective tissue, having no evident histo-morphological characteristics. Trypsin digestion carried out on-tissue is shown to improve MALDI-MSI analysis of human lens capsules and affords high repeatability. Most importantly, MALDI-MSI analysis reveals a concentric distribution pattern of proteins such as apolipoprotein E (ApoE) and collagen IV alpha-1 on the anterior surface of surgically removed lens capsule, which may indicate direct or indirect effects of environmental and mechanical stresses on the human ocular lens.

  17. Electromagnetic wave propagation of wireless capsule endoscopy in human body

    Institute of Scientific and Technical Information of China (English)

    LIM; Eng-Gee; 王炤; 陈瑾慧; TILLO; Tammam; MAN; Ka-lok

    2013-01-01

    Wireless capsule endoscopy(WCE) is a promising technique which has overcome some limitations of traditional diagnosing tools, such as the comfortlessness of the cables and the inability of examining small intestine section. However, this technique is still far from mature and asks for the feasible improvements. For example, the relatively low transmission data rate and the absence of the real-time localization information of the capsule are all important issues. The studies of them rely on the understanding of the electromagnetic wave propagation in human body. Investigation of performance of WCE communication system was carried out by studying electromagnetic(EM) wave propagation of the wireless capsule endoscopy transmission channel. Starting with a pair of antennas working in a human body mimic environment, the signal transmissions and attenuations were examined. The relationship between the signal attenuation and the capsule(transmitter) position, and direction was also evaluated. These results provide important information for real-time localization of the capsule. Moreover, the pair of antennas and the human body were treated as a transmission channel, on which the binary amplitude shift keying(BASK) modulation scheme was used. The relationship between the modulation scheme, data rate and bit error rate was also determined in the case of BASK. With the obtained studies, it make possible to provide valuable information for further studies on the selection of the modulation scheme and the real-time localization of the capsules.

  18. Bushen Yisui Capsule ameliorates axonal injury in experimental autoimmune encephalomyelitis

    Institute of Scientific and Technical Information of China (English)

    Ling Fang; Lei Wang; Qi Zheng; Tao Yang; Hui Zhao; Qiuxia Zhang; Kangning Li; Li Zhou; Haiyang Gong; Yongping Fan

    2013-01-01

    A preliminary clinical study by our group demonstrated Bushen Yisui Capsule (formerly cal ed Er-huang Formula) in combination with conventional therapy is an effective prescription for the treat-ment of multiple sclerosis. However, its effect on axonal injury during early multiple sclerosis re-mains unclear. In this study, a MOG 35-55-immunized C57BL/6 mouse model of experimental au-toimmune encephalomyelitis was intragastrical y administered Bushen Yisui Capsule. The results showed that Bushen Yisui Capsule effectively improved clinical symptoms and neurological function of experimental autoimmune encephalomyelitis. In addition, amyloid precursor protein expression was down-regulated and microtubule-associated protein 2 was up-regulated. Experimental findings indicate that the disease-preventive mechanism of Bushen Yisui Capsule in experimental autoim-mune encephalomyelitis was mediated by amelioration of axonal damage and promotion of rege-neration. But the effects of the high-dose Bushen Yisui Capsule group was not better than that of the medium-dose and low-dose Bushen Yisui Capsule group in preventing neurological dysfunction.

  19. Effect of four different intraocular lenses on posterior capsule opacification

    Institute of Scientific and Technical Information of China (English)

    Rahmi; Duman; Fatih; Karel; Pelin; ?zyol; Can; Ates

    2015-01-01

    AIM: To evaluate the impact of 4 different intraocular lenses(IOLs) on posterior capsule opacification(PCO) by comparing the neodymium: yttrium-aluminum-garnet(Nd:YAG) laser capsulotomy rates.METHODS: This retrospective study included 4970 eyes of 4013 cataract patients who underwent phacoemulsification and IOL implantation between January 2000 and January 2008 by the same surgeon at one clinic. Four different IOLs were assessed. The outcome parameter was the incidence of Nd:YAG laser posterior capsulotomies.· RESULTS: An Nd:YAG laser posterior capsulotomy was performed in 153(3.07%) of the 4970 eyes. The mean follow-up time was 84 mo for all of the IOL groups. The percentage of eyes developing PCO was significantly greater for the acrylic hydrophilic IOLs than for the hydrophobic IOLs, although eyes with acrylic hydrophilic IOLs did not require Nd:YAG laser capsulotomy as soon as eyes with acrylic hydrophobic IOLs. There was no difference between the long-term PCO rates when 1-and 3-piece acrylic hydrophobic IOLs were compared or when IOLs made of the same material but with different haptic angles were compared.· CONCLUSION: In this study, eyes with acrylic hydrophilic IOLs were more likely to develop PCO than those with acrylic hydrophobic IOLs. The lens design(1-piece versus 3-piece and varying haptic angles) did not affect the PCO rate.

  20. Silicon-Class Ablators for NIC Ignition Capsules

    Science.gov (United States)

    Ho, Darwin; Salmonson, Jay; Haan, Steve

    2012-10-01

    We present design studies using silicon-class ablators (i.e., Si, SiC, SiB6, and SiB14) for NIC ignition capsules. These types of ablators have several advantages in that they: (a) require no internal dopant layers and are robust to M-band radiation; (b) have smooth outer surfaces; (c) have stable fuel-ablator interface; and (d) have good 1-D performance. The major disadvantage for some of the ablators in this class is the relatively smaller ablation stabilization. Consequently, the ablator is more susceptible to breakup caused by RT instabilities. However, smoother outer surfaces on this class of ablators can reduce the effect of RT instabilities. 2-D simulations of SiC ablators show ignition failure despite smooth surfaces and good 1-D performance. But SiB6 and SiB14 ablators exhibit promising behaviors. SiB6 (SiB14) ablators have high 1-D ignition margin and high peak core hydrodynamic pressure 880 (900) Gbar. The ablation scale length for SiB6 is longer than that for SiC and for SiB14 is comparable to that of plastic. Therefore, we expect acceptable performance for SiB6 and less RT growth for SiB14. 2-D simulations are now in progress.