Sample records for capons

  1. Low Expression of CAPON in Glioma Contributes to Cell Proliferation via the Akt Signaling Pathway

    Directory of Open Access Journals (Sweden)

    Shangfeng Gao


    Full Text Available CAPON is an adapter protein for nitric oxide synthase 1 (NOS1. CAPON has two isoforms in the human brain: CAPON-L (long form of CAPON and CAPON-S (short form of CAPON. Recent studies have indicated the involvement of CAPON in tumorigenesis beyond its classical role in NOS1 activity regulation. In this study, we found that the protein levels of CAPON-S, but not than CAPON-L, were significantly decreased in glioma tissues. Therefore, we established lentivirus-mediated stable cell lines with CAPON-S overexpression or down-regulation, and investigated the role of CAPON-S in the proliferation of glioma cells by using CCK8, EdU, and flow cytometry assays. Overexpression of CAPON-S reduced the cell variability and the percentage of EdU-positive cells, and arrested the cells in the G1 phase in glioma cells. Silencing of CAPON by short-hairpin RNA showed the opposite effects. Furthermore, an intracellular signaling array revealed that overexpression of CAPON-S resulted in a remarkable reduction in the phosphorylation of Akt and S6 ribosomal protein in glioma cells, which was further confirmed by Western blot. These findings suggest that CAPON may function as a tumor suppressor in human brain glioma and that the inactivation of the Akt signaling pathway caused by CAPON-S overexpression may provide insight into the underlying mechanism of CAPON in glioma cell proliferation.

  2. Toxicoinfectious botulism in commercial caponized chickens (United States)

    Trampel, D.W.; Smith, S.R.; Rocke, T.E.


    During the summer of 2003, two flocks of commercial broiler chickens experienced unusually high death losses following caponizing at 3 wk of age and again between 8 and 14 wk of age. In September, fifteen 11-wk-old live capons were submitted to the Iowa State University Veterinary Diagnostic Laboratory for assistance. In both flocks, the second episode of elevated mortality was associated with incoordination, flaccid paralysis of leg, wing, and neck muscles, a recumbent body posture characterized by neck extension, and diarrhea. No macroscopic or microscopic lesions were detected in affected chickens. Hearts containing clotted blood and ceca were submitted to the National Wildlife Health Center in Madison, WI. Type C botulinum toxin was identified in heart blood and ceca by mouse bioassay tests. Enzyme-linked immunosorbent assay tests on heart blood samples were also positive for type C botulinum toxin. Clostridium botulinum was isolated from the ceca and genes encoding type C botulinum toxin were detected in cecal contents by a polymerase chain reaction test. Chickens are less susceptible to botulism as they age, and this disease has not previously been documented in broilers as old as 14 wk of age. Wound contamination by spores of C. botulinum may have contributed to the unusually high death losses following caponizing.

  3. Composition and Physico-Chemical Properties of Meat from Capons Fed Cereals

    Institute of Scientific and Technical Information of China (English)

    Olga Díaz; Luisana Rodríguez; Alexandr Torres; Ángel Cobos


    Chemical composition, physico-chemical properties and fatty acid composition of breast and drumstick meat from capons (castrated male cockerels) fed cereals were studied. Three groups of capons were reared. One group was fed ad libitum the same commercial diet until the 4th mon of life. The last month of its life, the capons of this group were fed corn. The second and third group of capons were fed the same diet from caponization. The second group was fed mixture of corn (50%) and wheat (50%). The third group of capons was fed 2/3 corn and 1/3 mixture of corn (50%) and barley (50%). Capons were reared under free-range conditions and slaughtered at 150 d of age. Caponization was performed at 48 d. No signiifcant effects of feeding in chemical composition, pH, water holding capacity, drip and cooking losses and texture of the meat were observed. The meat of the third group (capons fed 83%corn) was more yellow and showed higher content of C18:2 than that of the other capons.

  4. The analysis of meat traits of Sussex cockerels and capons (S11) at different ages. (United States)

    Adamski, Marek; Kuźniacka, Joanna; Banaszak, Mirosław; Wegner, Marcin


    The aim of the study was to compare Sussex cockerels and capons as well as to estimate the influence of age on slaughter yield and meat quality. The tests were performed on cockerels and capons from strain S11 (Sussex). At 16, 18, and 20 wk of age, a dissection of the entire carcass was conducted. The breast and leg muscles were tested for physio-chemical traits, as well as chemical parameters. It was noted that, due to significant differences in BW of the eviscerated carcasses between wk 18 and 20 of slaughter, the best time to cease rearing S11 cockerels could be wk 20. However, for S11 capons, the optimal time for slaughter appeared to be wk 18 (no significant differences in BW and carcass weight or musculature between wk 18 and 20). The trait which did not differ between cockerels and capons slaughtered at different ages was slaughter yield. Fatness of the cockerels increased with age whilst the weight of capons' skin with subcutaneous fat was the same at wk 18 and 20 of evaluation. With increasing age, pH indicators of cockerels and capons' breast muscles were increasing; the water holding capacity of capons' breast muscles were also increasing. Both cockerels and capons showed darker color of breast muscle at wk 20 compared to wk 16 of evaluation. Redness of the breast muscle in the following periods of evaluation did not show significant differences, although with age, the yellowness of the cockerels and capons' breast muscle increased significantly. Among cockerels and capons, the water content in the breast and leg muscles were decreasing with age whilst the protein content was increasing. A significant growing tendency of the percentage of fat share in the breast and leg muscles with age was noted in the capon group. Conclusions for breeding practice are as follows: due to meat and quality traits, Sussex cockerels and capons can be used until wk 18 or 20 of life.

  5. Reduced-Dimension Noncircular-Capon Algorithm for DOA Estimation of Noncircular Signals

    Directory of Open Access Journals (Sweden)

    Weihua Lv


    Full Text Available The problem of the direction of arrival (DOA estimation for the noncircular (NC signals, which have been widely used in communications, is investigated. A reduced-dimension NC-Capon algorithm is proposed hereby for the DOA estimation of noncircular signals. The proposed algorithm, which only requires one-dimensional search, can avoid the high computational cost within the two-dimensional NC-Capon algorithm. The angle estimation performance of the proposed algorithm is much better than that of the conventional Capon algorithm and very close to that of the two-dimensional NC-Capon algorithm, which has a much higher complexity than the proposed algorithm. Furthermore, the proposed algorithm can be applied to arbitrary arrays and works well without estimating the noncircular phases. The simulation results verify the effectiveness and improvement of the proposed algorithm.

  6. Increased expression in dorsolateral prefrontal cortex of CAPON in schizophrenia and bipolar disorder.

    Directory of Open Access Journals (Sweden)

    Bin Xu


    Full Text Available BACKGROUND: We have previously reported linkage of markers on chromosome 1q22 to schizophrenia, a finding supported by several independent studies. Within this linkage region, we have identified significant linkage disequilibrium between schizophrenia and markers within the gene for carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase (CAPON. Prior sequencing of the ten exons of CAPON failed to reveal a coding mutation associated with illness. METHODS AND FINDINGS: We screened a human fetal brain cDNA library and identified a new isoform of CAPON that consists of the terminal two exons of the gene, and verified the expression of the predicted corresponding protein in human dorsolateral prefrontal cortex (DLPFC. We examined the expression levels of both the ten-exon CAPON transcript and this new isoform in postmortem brain samples from the Stanley Array Collection. Quantitative real-time PCR analysis of RNA from the DLPFC in 105 individuals (35 with schizophrenia, 35 with bipolar disorder, and 35 psychiatrically normal controls revealed significantly (p < 0.005 increased expression of the new isoform in both schizophrenia and bipolar disorder. Furthermore, this increased expression was significantly associated (p < 0.05 with genotype at three single-nucleotide polymorphisms previously identified as being in linkage disequilibrium with schizophrenia. CONCLUSION: Based on the known interactions between CAPON, neuronal nitric oxide synthase (nNOS, and proteins associated with the N-methyl-D-aspartate receptor (NMDAR complex, overexpression of either CAPON isoform would be expected to disrupt the association between nNOS and the NMDAR, leading to changes consistent with the NMDAR hypofunctioning hypothesis of schizophrenia. This study adds support to a role of CAPON in schizophrenia, produces new evidence implicating this gene in the etiology of bipolar disorder, and suggests a possible mechanism of action of CAPON in psychiatric illness.

  7. Capon-based single-snapshot DOA estimation in monostatic MIMO radar (United States)

    Hassanien, Aboulnasr; Amin, Moeness G.; Zhang, Yimin D.; Ahmad, Fauzia


    We consider the problem of single snapshot direction-of-arrival (DOA) estimation of multiple targets in monostatic multiple-input multiple-output (MIMO) radar. When only a single snapshot is used, the sample covariance matrix of the data becomes non-invertible and, therefore, does not permit application of Capon-based DOA estimation techniques. On the other hand, low-resolution techniques, such as the conventional beamformer, suffer from biased estimation and fail to resolve closely spaced sources. In this paper, we propose a new Capon-based method for DOA estimation in MIMO radar using a single radar pulse. Assuming that the angular locations of the sources are known a priori to be located within a certain spatial sector, we employ multiple transmit beams to focus the transmit energy of multiple orthogonal waveforms within the desired sector. The transmit weight vectors are carefully designed such that they have the same transmit power distribution pattern. As compared to the standard MIMO radar, the proposed approach enables transmitting an arbitrary number of orthogonal waveforms. By using matched-filtering at the receiver, the data associated with each beam is extracted yielding a virtual data snapshot. The total number of virtual snapshots is equal to the number of transmit beams. By choosing the number of transmit beams to be larger than the number of receive elements, it becomes possible to form a full-rank sample covariance matrix. The Capon beamformer is then applied to estimate the DOAs of the targets of interest. The proposed method is shown to have improved DOA estimation performance as compared to conventional single-snapshot DOA estimation methods.

  8. Kali Argyriadis, Stefania Capone (Dir.), La religion des orisha. Un champ social transnational en pleine recomposition



    Cet ouvrage, né sous la direction de deux chercheuses spécialistes des études afro-américaines – Stefania Capone, dont les recherches portent sur la transnationalisation et la réinvention de l’africanité (on rappelle Les Yoruba du Nouveau Monde : religion, ethnicité et nationalisme noir aux États-Unis, Paris, Karthala, 2005) et Kali Argyriadis, qui a étudié longtemps la santería cubaine et notamment publié La religion à La Havane. Actualité des représentations et des pratiques cultuelles hava...

  9. "The word was sung, the word was bound" / Lester Capon

    Index Scriptorium Estoniae

    Capon, Lester, 1951-


    4. rahvusvaheline köitekunsti näitus-konkurss "Scripta manent" Eesti Tarbekunsti- ja Disainimuuseumis 9. jaanuarini 2011. Köita tuli Veljo Tormise "Lauldud sõna". Jeff Clementsi, Katinka Keusi (Holland), Lolita Grabauskiene-Tarbunaite (Leedu), Tiina Piisangu, Maila Käose, Ruuda Maarandi töödest

  10. An Amplitude Spectral Capon Estimator with a Variable Filter Length

    DEFF Research Database (Denmark)

    Nielsen, Jesper Kjær; Smaragdis, Paris; Christensen, Mads Græsbøll;


    The filter bank methods have been a popular non-parametric way of computing the complex amplitude spectrum. So far, the length of the filters in these filter banks has been set to some constant value independently of the data. In this paper, we take the first step towards considering the filter...

  11. Application of capon method to direct position determination

    Directory of Open Access Journals (Sweden)

    Liran Tzafri


    Full Text Available The direct position determination (DPD approach is a single-step method which uses the Maximum Likelihood estimator to localize sources emitting electromagnetic energy using combined data from all available sensors. The DPD is known to outperform the traditional 2-step methods under low Signal to Noise Ratio (SNR conditions. We propose an improvement to the DPD approach, using the well known minimum-variance-distortionless-response (MVDR approach. Unlike Maximum Likelihood, the number of sources need not be known before applying the method. The combination of both the direct approach and MVDR yields unprecedented localization accuracy and resolution for weak sources. We demonstrate this approach on the problem of multistatic radar, but the method can easily be extended to general localization problems.

  12. Capon and Bartlett Beamforming: Threshold Effect in Direction-of-Arrival Estimation Error and On the Probability of Resolution (United States)


    used to compllte i.(• P"’ ,,(0) match the K array responses existing in the true dlat covariaI(e H.R for Ok, k = 1. 2, .... , . hIit ersource, 12/10/2004 10 7% MIT Lincoln Laboratory, All rights reserved 11 7. ------------------------------------------------------------- 12 % SET RUN ...PARAMETERS ... 13 7.------------------- 14 7% Define GLOBAL variables 15 global run.params; 16 17 7% Define model parameters... 18 19 run -params.N = 18

  13. Stefania Capone, Les Yoruba du Nouveau Monde. Religion, ethnicité et nationalisme noir aux États-UnisParis, Karthala, 2005, 395 p.Terry Rey



    The global diffusion of Yoruba religious culture is one of the most impressive stories in the modern history of religion. For a once local “traditional” West African religion to have not only survived the transatlantic slave trade but to have since grown to count tens of millions of adherents (mostly in Africa and the Americas, though increasingly in Europe and Asia) is testimony to the remarkable depth, beauty, and resilience of Yoruba orisha (spirit) cults and the ifá divinatory system, whi...

  14. 复方柴胡散治疗鸡尿酸盐沉积效果初探%Preliminary Study on the Treatment Effect of the Aggradation of the Salt of Caponizing Uric Acid with the Compound Elixir of Chaihu

    Institute of Scientific and Technical Information of China (English)




  15. Outsiders' Art (United States)

    Gehring, John


    Slam poetry was born in the Green Mill Tavern, a one-time Chicago speakeasy where Al Capone imbibed, when a construction worker and poet named Marc Smith revolutionized poetry readings with an Uptown Poetry Slam in 1986. Slam borrows heavily from the rhythms and wordplay of rap and hip-hop, as well as the stream of consciousness and metaphysical…

  16. Works by Henry Wiss. Collegiate Legacy: Emeritus Faculty Exhibition.


    Wiss, Henry H.


    Exhibition of works by College of Architecture and Urban Studies emeritus faculty, celebrating the 50th anniversary of the college. Curated by Truman Capone and Deb Sim. Moss Arts Center, Virginia Tech. HENRY WISS. (left)Mountains. 1950-60. (right) Cowboy. 1950-60. Watercolor on paper. Miller Off Main Gallery/Collection of Robert Miller.

  17. APES Beamforming Applied to Medical Ultrasound Imaging

    DEFF Research Database (Denmark)

    Blomberg, Ann E. A.; Holfort, Iben Kraglund; Austeng, Andreas


    Recently, adaptive beamformers have been introduced to medical ultrasound imaging. The primary focus has been on the minimum variance (MV) (or Capon) beamformer. This work investigates an alternative but closely related beamformer, the Amplitude and Phase Estimation (APES) beamformer. APES offers...

  18. "Walter Gropius" by Dean Carter. Exhibition of College of Architecture and Urban Studies Timeline and Portrait Busts.


    Carter, Dean


    DEAN CARTER. Walter Gropius. Cast bronze. The Art Collection / Virginia Tech Foundation Exhibition of portrait busts and the timeline of the history College of Architecture and Urban Studies, on the occasion of the 50th anniversary of the College. Curated by Truman Capone and Deb Sim. Francis T. Eck Exhibition Corridor, Moss Arts Center, Virginia Tech. Image 13

  19. Drug: D00786 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00786 Drug Tolcapone (JAN/USAN/INN); Tasmar (TN) C14H11NO5 273.0637 273.2408 D00786.gif Antiparkinson...12) Dopaminergic synapse map07057 Antiparkinsonian agents map07216 Catecholamine ...capone (JAN/USAN/INN) USP drug classification [BR:br08302] Antiparkinson Agents Antiparkinson

  20. High-resolution vertical imaging of the troposphere and lower stratosphere using the new MU radar system (United States)

    Luce, H.; Hassenpflug, G.; Yamamoto, M.; Fukao, S.


    In the present paper, a new application of the range imaging technique called Frequency Interferometry Imaging (FII) or Range Imaging (RIM), performed in April 2005, is shown using the new 46.5-MHz Middle and Upper (MU) atmosphere radar system (Shigaraki, Japan). Height-time images of brightness distribution have been computed at the highest resolution ever obtained for imaging with VHF radars in the troposphere and, for the very first time, in the lower stratosphere, up to about 22 km. The images were produced by processing signals obtained with an initial range-resolution of Δr=150 m and five equally-spaced frequencies within Δf=1.0 MHz, with the adaptive Capon method. These values represent an improvement of a factor 2 over all the previous published experiments at VHF, which were performed with Δr=300 m and Δf=0.5 MHz. The Capon images present realistic and self-consistent features, and reveal many more organized structures than the height-time SNR plots at the initial range-resolution. For example, the Capon images show persistent enhanced brightness layers significantly thinner than 150 m in the stratosphere, which are impossible to track with the standard single-frequency mode owing to a lack of range resolution. These observations thus support the idea of strong stratification even at vertical scales much smaller than 100 m, as suggested by recent high-resolution temperature observations by balloons (Dalaudier et al., 1994). We also present comparisons of Capon images with patterns obtained from the dual-FDI technique and two parametric methods (the MUSIC algorithm and the newly-introduced Maximum Entropy Method based on an auto-regressive (AR) model). The comparisons confirm the insufficiencies of the dual-FDI technique and indicate that parametric methods such as MEM and the MUSIC algorithm can help to validate the Capon images when the parametric methods provide similar patterns.

  1. Joint DOA and Fundamental Frequency Estimation Methods based on 2-D Filtering

    DEFF Research Database (Denmark)

    Jensen, Jesper Rindom; Christensen, Mads Græsbøll; Jensen, Søren Holdt


    It is well-known that filtering methods can be used for processing of signals in both time and space. This comprises, for example, fundamental frequency estimation and direction-of-arrival (DOA) estimation. In this paper, we propose two novel 2-D filtering methods for joint estimation...... of the fundamental frequency and the DOA of spatio-temporarily sampled periodic signals. The first and simplest method is based on the 2-D periodogram, whereas the second method is a generalization of the 2-D Capon method. In the experimental part, both qualitative and quantitative measurements show that the proposed...... methods are well-suited for solving the joint estimation problem. Furthermore, it is shown that the methods are able to resolve signals separated sufficiently in only one dimension. In the case of closely spaced sources, however, the 2-D Capon-based method shows the best performance....

  2. Experimental Study of High-Range-Resolution Medical Acoustic Imaging for Multiple Target Detection by Frequency Domain Interferometry (United States)

    Kimura, Tomoki; Taki, Hirofumi; Sakamoto, Takuya; Sato, Toru


    We employed frequency domain interferometry (FDI) for use as a medical acoustic imager to detect multiple targets with high range resolution. The phase of each frequency component of an echo varies with the frequency, and target intervals can be estimated from the phase variance. This processing technique is generally used in radar imaging. When the interference within a range gate is coherent, the cross correlation between the desired signal and the coherent interference signal is nonzero. The Capon method works under the guiding principle that output power minimization cancels the desired signal with a coherent interference signal. Therefore, we utilize frequency averaging to suppress the correlation of the coherent interference. The results of computational simulations using a pseudoecho signal show that the Capon method with adaptive frequency averaging (AFA) provides a higher range resolution than a conventional method. These techniques were experimentally investigated and we confirmed the effectiveness of the proposed method of processing by FDI.

  3. High-resolution wave number spectrum using multi-point measurements in space – the Multi-point Signal Resonator (MSR technique

    Directory of Open Access Journals (Sweden)

    Y. Narita


    Full Text Available A new analysis method is presented that provides a high-resolution power spectrum in a broad wave number domain based on multi-point measurements. The analysis technique is referred to as the Multi-point Signal Resonator (MSR and it benefits from Capon's minimum variance method for obtaining the proper power spectral density of the signal as well as the MUSIC algorithm (Multiple Signal Classification for considerably reducing the noise part in the spectrum. The mathematical foundation of the analysis method is presented and it is applied to synthetic data as well as Cluster observations of the interplanetary magnetic field. Using the MSR technique for Cluster data we find a wave in the solar wind propagating parallel to the mean magnetic field with relatively small amplitude, which is not identified by the Capon spectrum. The Cluster data analysis shows the potential of the MSR technique for studying waves and turbulence using multi-point measurements.

  4. Hospital marketing. (United States)

    Carter, Tony


    This article looks at a prescribed academic framework for various criteria that serve as a checklist for marketing performance that can be applied to hospital marketing organizations. These guidelines are drawn from some of Dr. Noel Capon of Columbia University's book Marketing Management in the 21st Century and applied to actual practices of hospital marketing organizations. In many ways this checklist can act as a "marketing" balanced scorecard to verify performance effectiveness and develop opportunities for innovation.

  5. High-resolution vertical imaging of the troposphere and lower stratosphere using the new MU radar system

    Directory of Open Access Journals (Sweden)

    H. Luce


    Full Text Available In the present paper, a new application of the range imaging technique called Frequency Interferometry Imaging (FII or Range Imaging (RIM, performed in April 2005, is shown using the new 46.5-MHz Middle and Upper (MU atmosphere radar system (Shigaraki, Japan. Height-time images of brightness distribution have been computed at the highest resolution ever obtained for imaging with VHF radars in the troposphere and, for the very first time, in the lower stratosphere, up to about 22 km. The images were produced by processing signals obtained with an initial range-resolution of Δr=150 m and five equally-spaced frequencies within Δf=1.0 MHz, with the adaptive Capon method. These values represent an improvement of a factor 2 over all the previous published experiments at VHF, which were performed with Δr=300 m and Δf=0.5 MHz. The Capon images present realistic and self-consistent features, and reveal many more organized structures than the height-time SNR plots at the initial range-resolution. For example, the Capon images show persistent enhanced brightness layers significantly thinner than 150 m in the stratosphere, which are impossible to track with the standard single-frequency mode owing to a lack of range resolution. These observations thus support the idea of strong stratification even at vertical scales much smaller than 100 m, as suggested by recent high-resolution temperature observations by balloons (Dalaudier et al., 1994. We also present comparisons of Capon images with patterns obtained from the dual-FDI technique and two parametric methods (the MUSIC algorithm and the newly-introduced Maximum Entropy Method based on an auto-regressive (AR model. The comparisons confirm the insufficiencies of the dual-FDI technique and indicate that parametric methods such as MEM and the MUSIC algorithm can help to validate the Capon images when the parametric methods provide similar patterns.

  6. Aislamiento y caracterización de Mycoplasma pulmones de cerdos provenientes de mataderos


    Copes, Julio; Nievas, Fabián; Cerdá, Raúl Oscar; Perfumo, Carlos J.


    Se realizó un estudio microbiológico de 100 pulmones obtenidos al azar provenientes de capones y hembras sin servicio faenados en diferentes mataderos. Estos fueron clasificados macroscópicamente en pulmones con lesiones neumónicas (CLN) (43) y sin lesiones neumónicas (SLN) (57). Las muestras fueron procesadas para realizar el aislamiento y caracterización de microorganismos perteneciente al género Mycoplasma, en particular Mycoplasma hyorhinis y Mycoplasma hyosynoviae. De casos seleccionados...

  7. Some New Results on the Estimation of Sinusoids in Noise

    DEFF Research Database (Denmark)

    Nielsen, Jesper Kjær


    estimation is extended in an interesting way by selecting the filter length of the Capon filter in a data-adaptive fashion. Finally, the recently proposed sampling scheme called compressed sensing is analysed in the context of estimating continuous parameter such as the frequency parameter and the direction......-of-arrival, and it is shown that compressed sensing decreases the estimation accuracy of such parameters. Although the estimation problems considered in this thesis are primarily analysed in the context of speech and audio applications, the results are useful in a wider range of applications. Along these lines, the main...

  8. High Resolution Krylov Space 3-D Wavenumber-Frequency Analysis (United States)


    wavenumber-frequency distri- bution of signal modes. That is, PPER (k, f, t) = eH(k) R̂[f, t] e(k). (3) Different from eq.(2), here R̂[f, t] is a time... PPER (k, f, t) frequency f w av en um be r k Capon wavenumber frequency analysis 0.4 0.5 0.6 0.7 0.8 0.9 1 0.5 0.4 0.3 0.2 0.1 0 0.1 0.2 0.3 0.4 0.5 30

  9. Fluctuations of the SNR at the output of the MVDR with Regularized Tyler Estimators

    KAUST Repository

    Elkhalil, Khalil


    This paper analyzes the statistical properties of the signal-to-noise ratio (SNR) at the output of the Capon\\'s minimum variance distortionless response (MVDR) beamformers when operating over impulsive noises. Particularly, we consider the supervised case in which the receiver employs the regularized Tyler estimator in order to estimate the covariance matrix of the interference-plus-noise process using n observations of size N×1N×1. The choice for the regularized Tylor estimator (RTE) is motivated by its resilience to the presence of outliers and its regularization parameter that guarantees a good conditioning of the covariance estimate. Of particular interest in this paper is the derivation of the second order statistics of the SINR. To achieve this goal, we consider two different approaches. The first one is based on considering the classical regime, referred to as the n-large regime, in which N is assumed to be fixed while n grows to infinity. The second approach is built upon recent results developped within the framework of random matrix theory and assumes that N and n grow large together. Numerical results are provided in order to compare between the accuracies of each regime under different settings.

  10. 墨尔本风暴工资帽违规及思想理论

    Institute of Scientific and Technical Information of China (English)



    @@ Part(a):Melbourne Storm Salary Cap Breach On April 22,one of the biggest scandals in rugby league history was revealed.Based on the article of NRL hit Melbourne Storm with$1.5 million salary cap breach in The Daily Telegraph on April 22,the NRL chief executive David Gallop stated that"The Storm has engaged in a long-term system of operating what might conveniently be called two sets of books.To their credit this morning the Storm representatives have come in and confessed to a well-organised system of paying players outside the cap.On what we know this amounted to$1.7 million over the last five years,including approximately$700,000 in 2010."

  11. Development of a Novel NMR-based Rheb GTPase Assay and Molecular Characterization of TSC2 GAP Activity (United States)


    pH 8, 150 mM NaCl, 5 mM MgCl2, 10% glycerol, 10 mM imidazole, 10 mM b-mercaptoethanol, 0.1% Nonidet P - 40 , 0.1 mMGDP, 1 mM phenylmethylsulfonyl...p21. Biochemistry 29, 6058–6065 (1990). 40 . P . H. Seeburg, W. W. Colby, D. J. Capon, D. V. Goeddel, A. D. Levinson, Biological properties of human c...T I C L EG T P H Y D R O L Y S I SCharacterization of the Intrinsic and TSC2-GAP–Regulated GTPase Activity of Rheb by Real-Time NMR Christopher B

  12. Direct analysis of acetate and other volatile fatty acids in marine pore water by 2-dimensional ion chromatography-mass spectrometry (2D IC-MS) – A case study from Aarhus Bay (Denmark)

    DEFF Research Database (Denmark)

    Glombitza, Clemens; Lever, Mark; Jørgensen, Bo Barker

    Volatile fatty acids (VFA) such as formate, acetate, propionate and butyrate represent important intermediates in the anaerobic degradation of organic matter by microorganisms (Capone and Kiene, 1988). Knowledge on the concentrations and fluxes of these substrates, which are both end products...... and energy substrates of microbial metabolism is a key factor to determining energetic limits of sub-surface life and constraining the spatial extent of the so-called deep biosphere (Hoehler, 2007). Over the past 3 decades, numerous studies have quantified VFAs in marine pore water (e.g. Sansone and Martens...... µM. Analysis time is about 36 min per sample resulting in a sample throughput of more than 35 samples per day. In a first case study, we applied our novel procedure to pore water samples obtained from surface and sub-surface sediments of Aarhus Bay (Denmark). REFERENCES Albert, D.B., Martens, C...

  13. Optimal and adaptive methods of processing hydroacoustic signals (review) (United States)

    Malyshkin, G. S.; Sidel'nikov, G. B.


    Different methods of optimal and adaptive processing of hydroacoustic signals for multipath propagation and scattering are considered. Advantages and drawbacks of the classical adaptive (Capon, MUSIC, and Johnson) algorithms and "fast" projection algorithms are analyzed for the case of multipath propagation and scattering of strong signals. The classical optimal approaches to detecting multipath signals are presented. A mechanism of controlled normalization of strong signals is proposed to automatically detect weak signals. The results of simulating the operation of different detection algorithms for a linear equidistant array under multipath propagation and scattering are presented. An automatic detector is analyzed, which is based on classical or fast projection algorithms, which estimates the background proceeding from median filtering or the method of bilateral spatial contrast.

  14. In-vivo studies of new vector velocity and adaptive spectral estimators in medical ultrasound

    DEFF Research Database (Denmark)

    Hansen, Kristoffer Lindskov

    observation window compared to the conventional spectral Doppler method. The thesis shows, that novel information can be obtained with vector velocity methods providing quantitative estimates of blood flow and insight in to the complexity of fluid dynamics. This could give the clinician a new tool......In this PhD project new ultrasound techniques for blood flow measurements have been investigated in-vivo. The focus has mainly been on vector velocity techniques and four different approaches have been examined: Transverse Oscillation, Synthetic Transmit Aperture, Directional Beamforming and Plane...... Wave Excitation. Furthermore two different adaptive spectral estimators have been investigated: Blood spectral Power Capon method (BPC) and Blood Amplitude and Phase Estimation method (BAPES). The novel techniques investigated in this thesis are developed to circumvent some of the main limitations...

  15. Fast Spectral Velocity Estimation Using Adaptive Techniques: In-Vivo Results

    DEFF Research Database (Denmark)

    Gran, Fredrik; Jakobsson, Andreas; Udesen, Jesper;


    Adaptive spectral estimation techniques are known to provide good spectral resolution and contrast even when the observation window(OW) is very sbort. In this paper two adaptive techniques are tested and compared to the averaged perlodogram (Welch) for blood velocity estimation. The Blood Power...... spectral Capon (BPC) method is based on a standard minimum variance technique adapted to account for both averaging over slowtime and depth. The Blood Amplitude and Phase Estimation technique (BAPES) is based on finding a set of matched filters (one for each velocity component of interest) and filtering...... the blood process over slow-time and averaging over depth to find the power spectral density estimate. In this paper, the two adaptive methods are explained, and performance Is assessed in controlled steady How experiments and in-vivo measurements. The three methods were tested on a circulating How rig...

  16. A frequency domain radar interferometric imaging (FII) technique based on high-resolution methods (United States)

    Luce, H.; Yamamoto, M.; Fukao, S.; Helal, D.; Crochet, M.


    In the present work, we propose a frequency-domain interferometric imaging (FII) technique for a better knowledge of the vertical distribution of the atmospheric scatterers detected by MST radars. This is an extension of the dual frequency-domain interferometry (FDI) technique to multiple frequencies. Its objective is to reduce the ambiguity (resulting from the use of only two adjacent frequencies), inherent with the FDI technique. Different methods, commonly used in antenna array processing, are first described within the context of application to the FII technique. These methods are the Fourier-based imaging, the Capon's and the singular value decomposition method used with the MUSIC algorithm. Some preliminary simulations and tests performed on data collected with the middle and upper atmosphere (MU) radar (Shigaraki, Japan) are also presented. This work is a first step in the developments of the FII technique which seems to be very promising.

  17. Multitarget Identification and Localization Using Bistatic MIMO Radar Systems

    Directory of Open Access Journals (Sweden)

    Guisheng Liao


    Full Text Available A scheme for multitarget identification and localization using bistatic MIMO radar systems is proposed. Multitarget can be distinguished by Capon method, as well as the targets angles with respect to transmitter and receiver can be synthesized using the received signals. Thus, the locations of the multiple targets are obtained and spatial synchronization problem in traditional bistatic radars is avoided. The maximum number of targets that can be uniquely identified by proposed method is also analyzed. It is indicated that the product of the numbers of receive and transmit elements minus-one targets can be identified by exploiting the fluctuating of the radar cross section (RCS of the targets. Cramer-Rao bounds (CRB are derived to obtain more insights of this scheme. Simulation results demonstrate the performances of the proposed method using Swerling II target model in various scenarios.

  18. Comparisons of refractive index gradient and stability profiles measured by balloons and the MU radar at a high vertical resolution in the lower stratosphere

    Directory of Open Access Journals (Sweden)

    H. Luce


    Full Text Available Many experimental studies have demonstrated that VHF Stratosphere-Troposphere (ST radar echo power is proportional to the generalized refractive index gradient squared M2 when using a vertically oriented beam. Because humidity is generally negligible above the tropopause, VHF ST radars can thus provide information on the static stability (quantified by the squared Brunt-Väisälä frequency N2 at stratospheric heights and this capability is useful for many scientific applications. Most studies have been performed until now at a vertical resolution of 150 m or more. In the present paper, results of comparisons between radar- and (balloon borne radiosonde-derived M2 and N2 are shown at a better vertical resolution of 50 m with the MU radar (34.85° N, 136.15° E; Japan by benefiting from the range resolution improvement provided by the multi-frequency range imaging technique, using the Capon processing method. Owing to favorable winds in the troposphere, the radiosondes did not drift horizontally more than about 30 km from the MU radar site by the time they reached an altitude of 20 km. The measurements were thus simultaneous and almost collocated. Very good agreements have been obtained between both high resolution profiles of M2, as well as profiles of N2. It is also shown that this agreement can still be improved by taking into account a frozen-in advection of the air parcels by a horizontally uniform wind. Therefore, it can be concluded that 1 the range imaging technique with the Capon method really provides substantial range resolution improvement, despite the relatively weak Signal-to-Noise Ratios (SNR over the analyzed region of the lower stratosphere, 2 the proportionality of the radar echo power to M2 at a vertical scale down to 50 m in the lower stratosphere is experimentally demonstrated, 3 the MU radar can

  19. Time resolved dosimetry of human brain exposed to low frequency pulsed magnetic fields (United States)

    Paffi, Alessandra; Camera, Francesca; Lucano, Elena; Apollonio, Francesca; Liberti, Micaela


    An accurate dosimetry is a key issue to understanding brain stimulation and related interaction mechanisms with neuronal tissues at the basis of the increasing amount of literature revealing the effects on human brain induced by low-level, low frequency pulsed magnetic fields (PMFs). Most literature on brain dosimetry estimates the maximum E field value reached inside the tissue without considering its time pattern or tissue dispersivity. Nevertheless a time-resolved dosimetry, accounting for dispersive tissues behavior, becomes necessary considering that the threshold for an effect onset may vary depending on the pulse waveform and that tissues may filter the applied stimulatory fields altering the predicted stimulatory waveform’s size and shape. In this paper a time-resolved dosimetry has been applied on a realistic brain model exposed to the signal presented in Capone et al (2009 J. Neural Transm. 116 257-65), accounting for the broadband dispersivity of brain tissues up to several kHz, to accurately reconstruct electric field and current density waveforms inside different brain tissues. The results obtained by exposing the Duke’s brain model to this PMF signal show that the E peak in the brain is considerably underestimated if a simple monochromatic dosimetry is carried out at the pulse repetition frequency of 75 Hz.

  20. A Novel Coherence Reduction Method in Compressed Sensing for DOA Estimation

    Directory of Open Access Journals (Sweden)

    Jing Liu


    Full Text Available A novel method named as coherent column replacement method is proposed to reduce the coherence of a partially deterministic sensing matrix, which is comprised of highly coherent columns and random Gaussian columns. The proposed method is to replace the highly coherent columns with random Gaussian columns to obtain a new sensing matrix. The measurement vector is changed accordingly. It is proved that the original sparse signal could be reconstructed well from the newly changed measurement vector based on the new sensing matrix with large probability. This method is then extended to a more practical condition when highly coherent columns and incoherent columns are considered, for example, the direction of arrival (DOA estimation problem in phased array radar system using compressed sensing. Numerical simulations show that the proposed method succeeds in identifying multiple targets in a sparse radar scene, where the compressed sensing method based on the original sensing matrix fails. The proposed method also obtains more precise estimation of DOA using one snapshot compared with the traditional estimation methods such as Capon, APES, and GLRT, based on hundreds of snapshots.

  1. Passive Source Localization Using Compressively Sensed Towed Array

    Directory of Open Access Journals (Sweden)

    N. Suresh Kumar


    Full Text Available The objective of this work is to estimate the sparse angular power spectrum using a towed acoustic pressure sensor (APS array. In a passive towed array sonar, any reduction in the analog sensor signal conditioning receiver hardware housed inside the array tube, significantly improves the signal integrity and hence the localization performance. In this paper, a novel sparse acoustic pressure sensor (SAPS array architecture is proposed to estimate the direction of arrival (DOA of multiple acoustic sources. Bearing localization is effectively achieved by customizing the Capons spatial filter algorithm to suit the SAPS array architecture. Apart from the Monte Carlo simulations, the acoustic performance of the SAPS array with compressively sensed minimum variance distortionless response (CS-MVDR filter is demonstrated using a real passive towed array data. The proposed sparse towed array architecture promises a significant reduction in the analog signal acquisition receiver hardware, transmission data rate, number of snapshots and software complexity.Defence Science Journal, 2013, 63(6, pp.630-635, DOI:

  2. Low Complexity Moving Target Parameter Estimation For MIMO Radar using 2D-FFT

    KAUST Repository

    Jardak, Seifallah


    In multiple-input multiple-output radar, to estimate the target parameters, such as the reflection coefficient, spatial location, and Doppler shift, derived cost functions are usually optimized over a grid of points. The performance of such algorithms is directly affected by the grid resolution. Increasing the grid resolution enhances the resolution of the estimator but also increases its computational complexity exponentially. In this work, to estimate the parameters of a target, two reduced complexity optimum performance adaptive algorithms, which are based on Capon and amplitude and phase estimation, are presented. The proposed algorithm exploits the low order two-dimensional fast Fourier transform to determine the sub- optimal estimates of spatial location and Doppler shift, which are then used as the initial points for the derived steepest descent algorithm. In contrast to the grid search based algorithms, the proposed algorithm can optimally estimate on- and off-the-grid targets in very low computational complexity. Simulation results show that the mean-squared estimation error of the proposed estimators achieve the Craḿer-Rao lower bound.

  3. Single-snapshot DOA estimation by using Compressed Sensing (United States)

    Fortunati, Stefano; Grasso, Raffaele; Gini, Fulvio; Greco, Maria S.; LePage, Kevin


    This paper deals with the problem of estimating the directions of arrival (DOA) of multiple source signals from a single observation vector of an array data. In particular, four estimation algorithms based on the theory of compressed sensing (CS), i.e., the classical ℓ 1 minimization (or Least Absolute Shrinkage and Selection Operator, LASSO), the fast smooth ℓ 0 minimization, and the Sparse Iterative Covariance-Based Estimator, SPICE and the Iterative Adaptive Approach for Amplitude and Phase Estimation, IAA-APES algorithms, are analyzed, and their statistical properties are investigated and compared with the classical Fourier beamformer (FB) in different simulated scenarios. We show that unlike the classical FB, a CS-based beamformer (CSB) has some desirable properties typical of the adaptive algorithms (e.g., Capon and MUSIC) even in the single snapshot case. Particular attention is devoted to the super-resolution property. Theoretical arguments and simulation analysis provide evidence that a CS-based beamformer can achieve resolution beyond the classical Rayleigh limit. Finally, the theoretical findings are validated by processing a real sonar dataset.

  4. F-111E Flight Vibration and Acoustics Test Program. Part 1. Test Instrumentation, Test Procedure and Data Reduction (United States)


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  5. PREFACE: ARENA 2006—Acoustic and Radio EeV Neutrino detection Activities (United States)

    Thompson, Lee


    The International Conference on Acoustic and Radio EeV Neutrino Activities, ARENA 2006 was jointly hosted by the Universities of Northumbria and Sheffield at the City of Newcastle Campus of the University of Northumbria in June 2006. ARENA 2006 was the latest in a series of meetings which have addressed, either separately or jointly, the use of radio and acoustic sensors for the detection of highly relativistic particles. Previous successful meetings have taken place in Los Angeles (RADHEP, 2000), Stanford (2003) and DESY Zeuthen (ARENA 2005). A total of 50 scientists from across Europe, the US and Japan attended the conference presenting status reports and results from a number of projects and initiatives spread as far afield as the Sweden and the South Pole. The talks presented at the meeting and the proceedings contained herein represent a `snapshot' of the status of the fields of acoustic and radio detection at the time of the conference. The three day meeting also included two invited talks by Dr Paula Chadwick and Dr Johannes Knapp who gave excellent summaries of the related astroparticle physics fields of high energy gamma ray detection and high energy cosmic ray detection respectively. As well as a full academic agenda there were social events including a Medieval themed conference banquet at Lumley Castle and a civic reception kindly provided by the Lord Mayor of Newcastle and hosted at the Mansion House. Thanks must go to the International Advisory Board members for their input and guidance, the Local Organising Committee for their hard work in bringing everything together and finally the delegates for the stimulating, enthusiastic and enjoyable spirit in which ARENA 2006 took place. Lee Thompson International Advisory Board G. Anton, ErlangenD. Besson, Kansas J. Blümer, KarlsruheA. Capone, Rome H. Falcke, BonnP. Gorham, Hawaii G. Gratta, StanfordF. Halzen, Madison J. Learned, HawaiiR. Nahnhauer, Zeuthen A. Rostovtzev, MoscowD. Saltzberg, Los Angeles L

  6. 基于时频分析的多目标盲波束形成算法∗%A blind b eamforming algorithm for multitarget signals based on time-frequency analysis

    Institute of Scientific and Technical Information of China (English)

    刘亚奇; 刘成城; 赵拥军; 朱健东


    The existing blind beamforming methods are effective only under the condition that the source signals have some special statistical or structural characteristics. Additionally, the structure of cascade model is complicated and the stability of parallel model is poor when dealing with multi-target signals. To address these problems, a novel blind beamforming algorithm for multi-target signals based on time-frequency (TF) analysis is proposed in this paper. The received array signals are first transformed into time-frequency domain by using quadratic time-frequency distributions (TFDs). Then, the single-source auto-term TF points which show energy concentration at a single signal are extracted through three operations: (i) removing noise points by setting a reasonable threshold, (ii) separating auto-term TF points from cross-term points, and (iii) selecting the single-source auto-term TF points from the auto-term ones. Moreover, these single-source auto-term TF points are classified by the principal eigenvector of their spatial time-frequency distribution matrixes. For each class of TF points, the uncertain set of signal steering vector is given, whose radius is defined as the ultimate range between the center and the elements in the class. Within the uncertain set, an optimization algorithm is provided to get the optimal estimation of the signal steering vector. Finally, the blind beamforming for multi-target signals is achieved based on the Capon method, which can enhance the desired signals and suppress the noise and interference signals. In addition, the influence of parameters selection, the clustering method of unknown source number, and the computational complexity of the proposed algorithm are analyzed. The proposed algorithm can achieve parallel output of multi-target signals under the condition that the array manifold and the direction of arrival (DOA) are unknown. Also, the complex iterative solving processing may be avoided and special limitations on

  7. Nitric oxide in the nervous system: biochemical, developmental, and neurobiological aspects. (United States)

    Cossenza, Marcelo; Socodato, Renato; Portugal, Camila C; Domith, Ivan C L; Gladulich, Luis F H; Encarnação, Thaísa G; Calaza, Karin C; Mendonça, Henrique R; Campello-Costa, Paula; Paes-de-Carvalho, Roberto


    Nitric oxide (NO) is a very reactive molecule, and its short half-life would make it virtually invisible until its discovery. NO activates soluble guanylyl cyclase (sGC), increasing 3',5'-cyclic guanosine monophosphate levels to activate PKGs. Although NO triggers several phosphorylation cascades due to its ability to react with Fe II in heme-containing proteins such as sGC, it also promotes a selective posttranslational modification in cysteine residues by S-nitrosylation, impacting on protein function, stability, and allocation. In the central nervous system (CNS), NO synthesis usually requires a functional coupling of nitric oxide synthase I (NOS I) and proteins such as NMDA receptors or carboxyl-terminal PDZ ligand of NOS (CAPON), which is critical for specificity and triggering of selected pathways. NO also modulates CREB (cAMP-responsive element-binding protein), ERK, AKT, and Src, with important implications for nerve cell survival and differentiation. Differences in the regulation of neuronal death or survival by NO may be explained by several mechanisms involving localization of NOS isoforms, amount of NO being produced or protein sets being modulated. A number of studies show that NO regulates neurotransmitter release and different aspects of synaptic dynamics, such as differentiation of synaptic specializations, microtubule dynamics, architecture of synaptic protein organization, and modulation of synaptic efficacy. NO has also been associated with synaptogenesis or synapse elimination, and it is required for long-term synaptic modifications taking place in axons or dendrites. In spite of tremendous advances in the knowledge of NO biological effects, a full description of its role in the CNS is far from being completely elucidated.


    Directory of Open Access Journals (Sweden)

    Hussain AL SHAROUFI


    Full Text Available This study tries to show the importance of pragmatics in understanding human communication in an institutional setting. Speakers and listeners are actively involved in a negotiating process that leads to creating a cycle of actively changing contexts in which speech acts win their legitimacy of being real doers of action in real-time situations. Particular cultural repertoires in human societies facilitate language with a wealth of contextual resources that can help anchor meaning by favouring particular speech acts to other ones. In investigating some dialogical tactics practiced by some Kuwaiti customer service employees in Kuwait, I found that Mey’s pragmeme is the ideal outcome of these dialogic encounters. In Mey’s viewpoint, no speech act means anything without the cultural context in which it originates, a stance which casts a serious doubt on the semantico-syntactic analysis of speech acts in a Searlean sense. The communicative value of ethos in institutional encounters relies primarily on looking at meaning from a pragmatic perspective, to be more precise here from a pragmemic perspective. In order to assess the level of their socio-pragmatic awareness and their ability to depend on their socio-pragmatic resources to persuade their customers, I interviewed a group of customer service employees at some Kuwaiti banks. The results of the study showed cogently that bank employees in Kuwait have high socio-pragmatic awareness, which helped them significantly in attracting more customers to their banks. Those employees showed clear awareness of strategic positive politeness and effective usage of appropriate pragmemes, contextualized speech acts (Mey 2001, Capone 2005. Making promises, guaranteeing exceptional services, and pampering clients with versatile banking products are some of the socio-pragmatic strategies used by the aforementioned employees.

  9. Inspection of copper canister for spent nuclear fuel by means of ultrasound. Copper characterization, FSW monitoring with acoustic emission and ultrasonic imaging

    Energy Technology Data Exchange (ETDEWEB)

    Stepinski, Tadeusz (ed.); Engholm, Marcus; Olofsson, Tomas (Uppsala Univ., Signals and Systems, Dept. of Technical Sciences, Uppsala (Sweden))


    This report contains the research results concerning advanced ultrasound for the inspection of copper canisters for spent nuclear fuel obtained at Signals and Systems, Uppsala University in 2008. The first part of the report is concerned with aspects related to ultrasonic attenuation of copper material used for canisters. We present results of attenuation measurement performed for a number of samples taken from a real canister; two from the lid and four from different parts of canister wall. Ultrasonic attenuation of the material originating from canister lid is relatively low (less that 50 dB/m) and essentially frequency independent in the frequency range up to 5 MHz. However, for the material originating from the extruded canister part considerable variations of the attenuation are observed, which can reach even 200 dB/m at 3.5 MHz. In the second part of the report we present further development of the concept of the friction stir welding process monitoring by means of multiple sensors formed into a uniform circular array (UCA). After a brief introduction into modeling Lamb waves and UCA we focus on array processing techniques that enable estimating direction of arrival of multimodal Lamb waves. We consider two new techniques, the Capon beamformer and the broadband multiple signal classification technique (MUSIC). We present simulation results illustrating their performance. In the final part we present the phase shift migration algorithm for ultrasonic imaging of layered media using synthetic aperture concept. We start from explaining theory of the phase migration concept, which is followed by the results of experiments performed on copper blocks with drilled holes. We show that the proposed algorithm performs well for immersion inspection of metal objects and yields both improved spatial resolution and suppressed grain noise

  10. Whole body periodic acceleration is an effective therapy to ameliorate muscular dystrophy in mdx mice. (United States)

    Altamirano, Francisco; Perez, Claudio F; Liu, Min; Widrick, Jeffrey; Barton, Elisabeth R; Allen, Paul D; Adams, Jose A; Lopez, Jose R


    Duchenne muscular dystrophy (DMD) is a genetic disorder caused by the absence of dystrophin in both skeletal and cardiac muscles. This leads to severe muscle degeneration, and dilated cardiomyopathy that produces patient death, which in most cases occurs before the end of the second decade. Several lines of evidence have shown that modulators of nitric oxide (NO) pathway can improve skeletal muscle and cardiac function in the mdx mouse, a mouse model for DMD. Whole body periodic acceleration (pGz) is produced by applying sinusoidal motion to supine humans and in standing conscious rodents in a headward-footward direction using a motion platform. It adds small pulses as a function of movement frequency to the circulation thereby increasing pulsatile shear stress to the vascular endothelium, which in turn increases production of NO. In this study, we examined the potential therapeutic properties of pGz for the treatment of skeletal muscle pathology observed in the mdx mouse. We found that pGz (480 cpm, 8 days, 1 hr per day) decreased intracellular Ca(2+) and Na(+) overload, diminished serum levels of creatine kinase (CK) and reduced intracellular accumulation of Evans Blue. Furthermore, pGz increased muscle force generation and expression of both utrophin and the carboxy-terminal PDZ ligand of nNOS (CAPON). Likewise, pGz (120 cpm, 12 h) applied in vitro to skeletal muscle myotubes reduced Ca(2+) and Na(+) overload, diminished abnormal sarcolemmal Ca(2+) entry and increased phosphorylation of endothelial NOS. Overall, this study provides new insights into the potential therapeutic efficacy of pGz as a non-invasive and non-pharmacological approach for the treatment of DMD patients through activation of the NO pathway.

  11. Hard water softening effect of a baby cleanser

    Directory of Open Access Journals (Sweden)

    Walters RM


    Full Text Available Russel M Walters, Emmanuel Anim-Danso, Stephanie M Amato, Kimberly A Capone, M Catherine Mack, Lorena S Telofski, David A Mays Skin Care Research & Development, Johnson & Johnson Consumer Inc., Skillman, NJ, USA Background: Hard water is associated with atopic dermatitis (eczema. We wanted to determine if a baby cleanser and its individual components altered free ionized calcium (Ca2+ in a simulated hard water baby bath. For these studies, an in vitro determination of free Ca2+ in a simulated hard water baby bath, and an in vivo exploratory study of free Ca2+ absorption into skin from hard water were performed.Methods: Free Ca2+ was measured with an ion-sensitive electrode in vitro in hard water (100–500 ppm, Ca2+ before and after addition of the cleanser and/or its components. In an exploratory study, absorption of Ca2+ into skin from hard water was determined in three female participants (aged 21–29 years.Results: At an in-use dilution of 1%, the test cleanser reduced free Ca2+ from ~500 ppm to <200 ppm; a 10% in-use dilution bound virtually all free Ca2+. The anionic surfactant component contributed the most to this effect. In the exploratory in vivo study, we measured a reduction of ~15% in free Ca2+ from simulated hard water over 10 minutes.Conclusion: Baby cleansers can bind free Ca2+ and reduce the effective water hardness of bath water. Reducing the amount of free Ca2+ in the water will reduce the availability of the ion for binding to the skin. Altering or reducing free Ca2+ concentrations in bath water may be an important parameter in creating the ideal baby bath. Keywords: bath, cleanser, hard water, infant, neonate, surfactant

  12. Extended radar observations with the frequency radar domain interferometric imaging (FII) technique (United States)

    Luce, H.; Yamamoto, M.; Fukao, S.; Crochet, M.


    In this paper, we present high-resolution observations obtained with the Middle and Upper Atmosphere (MU) radar (Shigaraki, Japan, /34.85°N, /136.10°E) using the frequency radar domain interferometric imaging (FII) technique. This technique has recently been introduced for improving the range resolution capabilities of the mesosphere-stratosphere-troposphere (MST) radars which are limited by their minimum pulse length. The Fourier-based imaging, the Capon method have been performed with 5 equally spaced frequencies between 46.25 and 46.75MHz and with an initial range resolution of 300m. These results have been compared firstly to results obtained using the frequency domain interferometry (FDI) technique with Δf=0.5MHz and, secondly, to results from a classical Doppler beam swinging (DBS) mode applied with a range resolution of 150m. Thin echoing structures could be tracked owing to the improved radar range resolution and some complex structures possibly related to Kelvin Helmholtz instabilities have been detected. Indeed, these structures appeared within the core of a wind shear and were associated with intense vertical wind fluctuations. Moreover, a well-defined thin echo layer was found in an altitude range located below the height of the wind shear. The radar observations have not been fully interpreted yet because the radar configuration was not adapted for this kind of study and because of the lack of complementary information provided by other techniques when the interesting echoing phenomena occurred. However, the results confirm the high potentialities of the FII technique for the study of atmospheric dynamics at small scales.

  13. Risk management profile of etoricoxib: an example of personalized medicine

    Directory of Open Access Journals (Sweden)

    Paola Patrignani


    Full Text Available Paola Patrignani, Stefania Tacconelli, Marta L CaponeDepartment of Medicine and Center of Excellence on Aging, “G. D’Annunzio” University School of Medicine, and “Gabriele D’Annunzio” University Foundation, CeSI, Chieti, ItalyAbstract: The development of nonsteroidal anti-inflammatory drugs (NSAIDs selective for cyclooxygenase (COX-2 (named coxibs has been driven by the aim of reducing the incidence of serious gastrointestinal (GI adverse events associated with the administration of traditional (t NSAIDs – mainly dependent on the inhibition of COX-1 in GI tract and platelets. However, their use has unravelled the important protective role of COX-2 for the cardiovascular (CV system, mainly through the generation of prostacyclin. In a recent nested-case control study, we found that patients taking NSAIDs (both coxibs and tNSAIDs had a 35% increase risk of myocardial infarction. The increased incidence of thrombotic events associated with profound inhibition of COX-2-dependent prostacyclin by coxibs and tNSAIDs can be mitigated, even if not obliterated, by a complete suppression of platelet COX-1 activity. However, most tNSAIDs and coxibs are functional COX-2 selective for the platelet (ie, they cause a profound suppression of COX-2 associated with insufficient inhibition of platelet COX-1 to translate into inhibition of platelet function, which explains their shared CV toxicity. The development of genetic and biochemical markers will help to identify the responders to NSAIDs or who are uniquely susceptible at developing thrombotic or GI events by COX inhibition. We will describe possible strategies to reduce the side effects of etoricoxib by using biochemical markers of COX inhibition, such as whole blood COX-2 and the assessment of prostacyclin biosynthesis in vivo.Keywords: etoricoxib, nonsteroidal antiinflammatory drugs, COX-2, gastrointestinal toxicity, cardiovascular toxicity, prostacyclin


    Directory of Open Access Journals (Sweden)

    Eva María Olmedo Moreno


    Full Text Available Los informes sobre el EEES proponen un nuevo enfoque de aprendizaje basado en la construcción del conocimiento, que supone no sólo un cambio en la propuesta metodológica actual, sino que también del contexto cultural de aprendizaje que desencadene una nueva cultura de aprendizaje. Diversos trabajos, desde la perspectiva sociocultural (Gay y Cole, 1967; Rogoff y Lave, 1984; Scribner et al., 1982; Carraher, Carraher y Schliemann, 1985; Saxe, 1989; Capon y Kuhn, 1979; Buendía y Olmedo, 2002; Olmedo, Pegalajar y Buendía, 2011, insisten en la importancia del escenario en el que se desarrollan las acciones de aprendizaje y la necesidad de apostar por contextos permeables y enriquecidos por lo masculino y lo femenino (Calvo y Susinos, 2010. Este trabajo se centra en describir y reescribir para interpretar las relaciones de los objetos, presentados en fotografías por los y las participantes. Tres grupos de estudiantes de Posgrado de la Facultad de Ciencias de la Educación de la Universidad de Granada, que construyen el contexto cultural de aprendizaje desde su perspectiva, diferenciada por la identidad de género. Mediante la investigación basada en la imagen, subyace como principal conclusión que a pesar de los esfuerzos realizados en la institución universitaria por cambiar hacia un modelo de aprendizaje constructivista, aún no está asumido completamente por los y las estudiantes, puesto que las modalidades de aprendizaje menos representadas son propias a este. El género no se ha incluido como orientador en las nuevas teorías y metodologías universitarias; las mujeres tratan de adaptar y reconfigurar el espacio a las necesidades demandadas por las nuevas acciones, haciéndolos más versátiles, y los hombres más conservadores y reafirmados en modalidades de carácter prioritariamente individuales, situadas en entornos tradicionales de aprendizaje como es un aula o su habitación de estudio.

  15. The role of the microfissuration of the rock matrix in the abrasion resistance of ornamental granitic rocks (United States)

    Rodríguez-Rey, Angel; Sanchez-Delgado, Nuria; Camino, Clara; Calleja, Lope; Ruiz de Argandoña, Vicente G.; Setien, Alexia


    The microcrack density and the abrasion resistance of five ornamental granites (Albero, Gris Alba, Mondariz, Rosa Porriño and Traspieles) from Galicia (NW Spain) have been quantified as part of a research aimed to interpret the cuttability of the rocks in relation to the petrophysical properties of the rock matrix. Large blocks from the quarries have been cut with an industrial saw and the microcrack density and the abrasion resistance have been measured in two surfaces: H, parallel to the cut surface; T, perpendicular both to the cut surface and the cutting direction. Both planes are perpendicular to the rift plane, as it is known in quarry works. The microcrack density has been quantified following an stereological procedure applied to polished sections imaged under scanning electron microscopy. The magnification of the images allowed the study of microcracks as narrow as 2 microns in aperture. The density has been quantified in terms of length of microcrack traces per surface unit so possible anisotropies of the microcrack network could be detected. The obtained values are in the typical range for this type of rocks although the Traspieles granite shows a higher value due to its weathering degree (H: 5.11, T: 5.37 mm/mm2). The values measured in the two surfaces (H and T) are quite similar in four of the rocks; only the Albero granite shows a marked anisotropy (H: 2.76 T: 3.53 mm/mm2). The abrasion resistance of the rocks has been measured following the european standard EN 14157:2004 using the capon method. The rocks can be classified in two groups according to their abrasion resistance. Rosa Porriño, Gris Alba and Mondariz granites are the more resistant to abrasion with values around 16-17 mm. Albero and Traspieles granites are less resistant with values higher than 19 mm. The results show a good correlation between the microcrack density and the abrasion resistance. As can be expected the rocks with high microcrack density show low abrasion resistance. The

  16. Estimation Method of Low Complexity DOA for MIMO Radar%低复杂度MIMO雷达波达方向的估计方法研究

    Institute of Scientific and Technical Information of China (English)


    In order to reduce the computational complexity for MIMO radar, this paper studies an algorithm that is based on the dimensionality reduction process of echo signals and two kinds of DOA estimation methods that are based on signal sub-space reconstruction (SSR) with sub-space reconstruction. By contrastive and simulative analyses of five kinds of algorithms, it comes to a conclusion that the RD-ESPRIT algorithm is much sensitive to the selection of reduced-dimensional matrix than other algorithms with special spectrum search, and lays more stresses on the rotational invariance of array flow types after dimension reduced. The RD polynomial rooting algorithm, RD-MUSIC algorithm and RD-Capon algorithm have higher estimation accuracy of angles. In addition, the computational complexity of the RD-ESPRIT algorithm and RD polynomial rooting algorithm is lower than other three types of algorithms, and the computational complexity of the RD-ESPRIT is lowest among those five algorithms.%  为了降低MIMO雷达的运算复杂度,研究了基于对回波信号降维处理算法和基于子空间重构的信号子空间重构(SSR)算法的两类波达方向(DOA)估计方法。通过对5种算法的对比和仿真分析可知:RD-ESPRIT算法相比其他空间谱搜索算法,对降维矩阵的选择较敏感,更强调降维后阵列流型的旋转不变性;RD-求根算法、RD-MUSIC算法和RD-Capon算法则有更好的角度估计性能;RD-ESPRIT算法和RD-求根算法运算量相比其他三种算法低一到两个数量级;RD-ESPRIT算法运算复杂度最小。

  17. Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits

    Directory of Open Access Journals (Sweden)

    Almind Katrine


    Full Text Available Abstract Background Several studies in multiple ethnicities have reported linkage to type 2 diabetes on chromosome 1q21-25. Both PKLR encoding the liver pyruvate kinase and NOS1AP encoding the nitric oxide synthase 1 (neuronal adaptor protein (CAPON are positioned within this chromosomal region and are thus positional candidates for the observed linkage peak. The C-allele of PKLR rs3020781 and the T-allele of NOS1AP rs7538490 are reported to strongly associate with type 2 diabetes in various European-descent populations comprising a total of 2,198 individuals with a combined odds ratio (OR of 1.33 [1.16–1.54] and 1.53 [1.28–1.81], respectively. Our aim was to validate these findings by investigating the impact of the two variants on type 2 diabetes and related quantitative metabolic phenotypes in a large study sample of Danes. Further, we intended to expand the analyses by examining the effect of the variants in relation to overweight and obesity. Methods PKLR rs3020781 and NOS1AP rs7538490 were genotyped, using TaqMan allelic discrimination, in a combined study sample comprising a total of 16,801 and 16,913 individuals, respectively. The participants were ascertained from four different study groups; the population-based Inter99 cohort (nPKLR = 5,962, nNOS1AP = 6,008, a type 2 diabetic patient group (nPKLR = 1,873, nNOS1AP = 1,874 from Steno Diabetes Center, a population-based study sample (nPKLR = 599, nNOS1AP = 596 from Steno Diabetes Center and the ADDITION Denmark screening study cohort (nPKLR = 8,367, nNOS1AP = 8,435. Results In case-control studies we evaluated the potential association between rs3020781 and rs7538490 and type 2 diabetes and obesity. No significant associations were observed for type 2 diabetes (rs3020781: pAF = 0.49, OR = 1.02 [0.96–1.10]; rs7538490: pAF = 0.84, OR = 0.99 [0.93–1.06]. Neither did we show association with overweight or obesity. Additionally, the PKLR and the NOS1AP genotypes were demonstrated not


    Energy Technology Data Exchange (ETDEWEB)

    NEALSON, H. K.


    This work involved the use of the Nano-SIMS Instrument at Lawrence Livermore Laboratory, in an effort to utilize this unique tool for experiments in Biology. The work consisted primarily of experiments to measure in real time, C and N fixation in cyanobacteria. The work revealed a number of the difficulties in using the nano-SIMS approach with biological material, but with collaboration from a number of individuals at USC and LLNL, major progress was made. The collaborators from LLNL were from the Chemistry Group (Dr. Peter Weber), and the Biology Group (Dr. Jennifer Pett-Ridge). In addition, there were a number of other scientists involved from LLNL. The USC group consisted of Dr. K.H. Nealson, the PI on the grant, Dr. R. Popa, a postdoctoral fellow and research associate at USC, Professor Douglas Capone, and Juliet Finze, a graduate student in biology. Two major experiments were done, both of which yielded new and exciting data. (1) We studied nitrogen and carbon fixation in Anabaena, demonstrating that fixation ofN occurred rapidly in the heterocysts, and that the fixed N was transported rapidly and completely to the vegetative cells. C fixation occurred in the vegetative cells, with labeled C remaining in these cells in support of their growth and metabolism. This work was accepted in the ISME Journal (Nature Publication), and published last month. (2) We studied nitrogen and carbon fixation in Trichodesmium, a non-heterocystous cyanobacterium that also fixes nitrogen. Interestingly, the nitrogen fixation was confined to regions within the filaments that seem to be identical to the so-called cyanophycaen granules. The fixed N is then transported to other parts of the cyanobacterium, as judged by movement of the heavy N throughout the filaments. On the basis of these very exciting results, we have applied for funding from the NSF to continue the collaboration with LLNL. The results of both studies were presented in the summer of 2007 at the Gordon Research

  19. Testosterone deficiency: a historical perspective

    Directory of Open Access Journals (Sweden)

    Eberhard Nieschlag


    Full Text Available The biological effects of the testes and testosterone are known since antiquity. Aristotle knew the effects of castration and his hypothesis on fertilization is one of the first scientific encounters in reproductive biology. Over centuries, castration has been performed as punishment and to produce obedient slaves, but also to preserve the soprano voices of prepubertal boys. The Chinese imperial (and other oriental courts employed castrates as overseers in harems who often obtained high-ranking political positions. The era of testis transplantation and organotherapy was initiated by John Hunter in London who transplanted testes into capons in 1786. The intention of his experiments was to prove the 'vital principle' as the basis for modern transplantation medicine, but Hunter did not consider endocrine aspects. Arnold Adolph Berthold postulated internal secretion from his testicular transplantation experiments in 1849 in Göttingen and is thus considered the father of endocrinology. Following his observations, testicular preparations were used for therapy, popularized by self-experiments by Charles-Edouard Brown-Séquard in Paris (1889, which can at best have placebo effects. In the 1920s Sergio Voronoff transplanted testes from animals to men, but their effectiveness was disproved. Today testicular transplantation is being refined by stem cell research and germ cell transplantation. Modern androgen therapy started in 1935 when Enrest Lacquer isolated testosterone from bull testes in Amsterdam. In the same year testosterone was chemically synthesized independently by Adolf Butenandt in Göttingen and Leopold Ruzicka in Basel. Since testosterone was ineffective orally it was either compressed into subcutaneous pellets or was used orally as 17α-methyl testosterone, now obsolete because of liver toxicity. The early phases of testosterone treatment coincide with the first description of the most prominent syndromes of hypogonadism by Klinefelter, by

  20. Joint DOD and DOA estimation for bistatic MIMO radar with arbitrary array using semi-real-valued MUSIC%任意阵列双基地 MIMO 雷达的半实值 MUSIC目标 DOD 和 DOA 联合估计

    Institute of Scientific and Technical Information of China (English)

    张秦; 张林让; 郑桂妹; 李兴成


    实值处理具有降低高自由度多输入多输出(multiple-input multiple-output,MIMO)雷达角度估计大计算量的优势。但受制于阵列的共轭对称性,对于任意阵列结构的双基地 MIMO 雷达发射角(direction of depar-ture,DOD)和接收角(direction of arrival,DOA)联合估计,若不做附加的预处理则无法实现实值操作,故将常规阵列实值处理的多重信号分类(multiple signal classification,MUSIC)超分辨算法推广至任意阵列结构的双基地MIMO 雷达。首先根据 MIMO 雷达的导向矢量共轭与镜像的对等性,提取接收信号协方差矩阵的实部,并对其进行特征分解得到“目标加倍”的信号子空间及其应对的噪声子空间;然后利用 Kronecker 积的特性对其进行降维处理,得到搜索区域减半的一维半实值域 MUSIC 谱,取出目标 DOD 真值与其镜像代入降维 Capon 算法来剔除虚拟峰值得到目标 DOD 估计真值;最后利用特征矢量得到模糊 DOA 估计值,采用方向余弦差最小范数方法得到目标 DOA 无模糊估计值。本文算法估计性能与一维搜索复数域 MUSIC 相当,计算量约降50%,且能够实现 DOD和 DOA 的自动配对。仿真结果证明了该算法的有效性。%Real-valued domain processing has the advantage of reducing the heavy computational complexity for multiple-input multiple-output (MIMO)radar angle estimation with large degrees of freedom.Unfortunate-ly,real-valued domain processing cannot be applied to bistatic MIMO radar with the arbitrary array structure for direction of departure (DOD)and direction of arrival (DOA)estimation except additional pre-processing be-cause the array do not have the characteristic of conjugate symmetry.Therefore,the multiple signal classifica-tion (MUSIC)super resolution algorithm for conventional array with the real-valued domain processing extends to the bistatic MIMO radar with the arbitrary array

  1. Atmospheric Nitrogen Inputs to the Ocean and their Impact (United States)

    Jickells, Tim D.


    Atmospheric Nitrogen Inputs to the Ocean and their Impact T Jickells (1), K. Altieri (2), D. Capone (3), E. Buitenhuis (1), R. Duce (4), F. Dentener (5), K. Fennel (6), J. Galloway (7), M. Kanakidou (8), J. LaRoche (9), K. Lee (10), P. Liss (1), J. Middleburg (11), K. Moore (12), S. Nickovic (13), G. Okin (14), A. Oschilies (15), J. Prospero (16), M. Sarin (17), S. Seitzinger (18), J. Scharples (19), P. Suntharalingram (1), M. Uematsu (20), L. Zamora (21) Atmospheric nitrogen inputs to the ocean have been identified as an important source of nitrogen to the oceans which has increased greatly as a result of human activity. The significance of atmospheric inputs for ocean biogeochemistry were evaluated in a seminal paper by Duce et al., 2008 (Science 320, 893-7). In this presentation we will update the Duce et al 2008 study estimating the impact of atmospheric deposition on the oceans. We will summarise the latest model estimates of total atmospheric nitrogen deposition to the ocean, their chemical form (nitrate, ammonium and organic nitrogen) and spatial distribution from the TM4 model. The model estimates are somewhat smaller than the Duce et al estimate, but with similar spatial distributions. We will compare these flux estimates with a new estimate of the impact of fluvial nitrogen inputs on the open ocean (Sharples submitted) which estimates some transfer of fluvial nitrogen to the open ocean, particularly at low latitudes, compared to the complete trapping of fluvial inputs on the continental shelf assumed by Duce et al. We will then estimate the impact of atmospheric deposition on ocean primary productivity and N2O emissions from the oceans using the PlankTOM10 model. The impacts of atmospheric deposition we estimate on ocean productivity here are smaller than those predicted by Duce et al impacts, consistent with the smaller atmospheric deposition estimates. However, the atmospheric input is still larger than the estimated fluvial inputs to the open ocean

  2. Tune measurement at GSI SIS-18. Methods and applications

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Rahul


    Two parallel tune measurement systems are installed at GSI SIS-18 based on different principles. The first is called the Tune, Orbit and POSition measurement system TOPOS. Its working principle involves direct digitization of BPM signals at 125 MSa/s, which is used for online bunch-by-bunch position calculation in FPGAs. In the course of this work, position calculation algorithms were developed and studied for real time implementation in the TOPOS FPGAs. The regression fit algorithm is found to be more efficient and robust in comparison to previously used weighted mean algorithm with the baseline restoration procedure. The second system is the Baseband Tune measurement system referred to as BBQ system. The operational principle of this system was conceived at the CERN Beam Instrumentation group and is based on direct diode detection. In the framework of this work, this system was optimized and brought into operation at GSI SIS-18. Front-end data from both systems are used to calculate the tune spectrum every 250-5000 beam revolutions or turns within SIS-18 based on the resolution requirement and the mode of operation. Advanced non-parametric spectrum estimation method like amplitude Capon estimator is compared to the conventional DFT based methods in terms of resolving power and computational requirements for the calculated spectrum. Further the TOPOS and BBQ systems are compared and characterized in terms of sensitivity, reliability and operational usage. The results from both systems are found to be consistent with each other and have their favoured regimes of operation. The effects on tune spectra obtained from both systems were studied with different types of excitations with excitation power levels up to 6 mW/Hz. These systems in association with other beam diagnostic devices at SIS-18 were used to conduct extensive experiments to understand the effect of high intensity beams on the tune spectrum. These careful measurements recorded all the relevant beam

  3. Perennial grasses traits as functional markers of grazing intensity in basaltic grasslands of Uruguay Rasgos de gramíneas perennes como marcadores funcionales de la intensidad de pastoreo en pastizales de basalto en Uruguay

    Directory of Open Access Journals (Sweden)

    Martin Jaurena


    los grupos funcionales se determinó la respuesta al incremento de la intensidad de pastoreo en un experimento con dos cargas de capones (0,78 and 1,56 unidades ganaderas ha-1 cuantificando la cobertura de dichas especies y los valores de sus rasgos. El contenido de MS y el área foliar específica fueron los rasgos que mejor describieron la respuesta de las gramíneas perennes al incremento de la carga animal y podrían ser utilizados como marcadores funcionales. Tres grupos funcionales fueron identificados. El nivel más bajo de carga animal se relacionó con el grupo funcional A (especies estivales, altas, con baja área foliar específica y alto contenido de MS y con el grupo funcional B (especies invernales altas y con niveles intermedios de rasgos foliares. Por otro lado, el nivel más elevado de carga animal se relacionó con el aumento del grupo funcional C (especies estivales, postradas, con alta área foliar específica y bajos contenidos de MS. Esta clasificación de una comunidad con alta diversidad de especies en tres grupos funcionales es un nuevo enfoque para desarrollar métodos simples y generales para el diagnóstico del estado de praderas naturales de la región basáltica en Uruguay y generar recomendaciones para su manejo.

  4. Proceedings of the Eleventh International Conference on Calorimetry in Particle Physics (United States)

    Cecchi, Claudia

    calorimeter / M. Martin (contribution not received) -- Minical options, description in MC, calibration, plans for test beam prototype / G. Eigen (contribution not received) -- Photodetector options for a scintillator heal / E. Popova (contribution not received) -- Very low background scintillators in DAMA project: results and perspectives / R. Bernabei -- EDELWEISS Ge cryogenics detectors: main performance and physics results / X. Navick (contribution not received) -- Review of massive underground detectors / A. Rubbia -- Review of neutrino telescopes underwater and under ice / A. Capone (contribution not received) -- The fluorescence detector of the Pierre Auger Observatory / R. Caruso -- The EUSO mission for the observation of ultra high energy cosmic rays from space / A. Petrolini -- Performance of a 3D imaging electromagnetic calorimeter for the AMSO2 space experiment / C. Adloff -- Beam test calibration of the balloon borne imaging calorimeter for the CREAM experiment / P. Maestro.

  5. PREFACE: First Mediterranean Conference on Classical and Quantum Gravity (MCCQG 2009) (United States)

    Basilakos, Spyros; Cadoni, Mariano; Cavaglia, Marco; Christodoulakis, Theodosios; Vagenas, Elias C.


    Fisica, Universidade de Sao Paulo, Brasil) Antoniadis, Ignatios (CERN, Geneva, Switzerland) Arminjon, Mayeul (CNRS, Section of Theoretical Physics, France) Banados, Max (University of Oxford, UK) Basilakos, Spyros (RCAAM, Academy of Athens, Greece) Bastos, Catarina (IST, Departamento de Física, Portugal) Bertolami, Orfeu (IST, Departamento de Física, Portugal) Bevilaqua, Leandro Ibiapina (Instituto de Fisica, Universidade de Sao Paulo, Brazil) Bezerra De Mello, Eugenio (Dept. de Física, CCEN Universidade Federal da Paraíba, Brazil) Blake, Russ (Readify Pty Ltd, Australia) Bogdanos, Charalampos (LPT-Orsay, France) Burinskii, Alexander (Gravity Research Group NSI, Russian Academy of Sciences, Russia) Cadonati, Laura (University of Massachusetts, Amherst, USA) Cadoni, Mariano (Università di Cagliari, Italy) Capone, Monica (University of Turin, Italy) Cavaglià, Marco (University of Mississippi, USA) Chirco, Goffredo (SISSA-International School for Advanced Studies, Italy) Christodoulakis, Theodosios (University of Athens, Greece) Domingues Zarro, Carlos Augusto ((IST, Departamento de Física, Portugal) Durrer, Ruth (Université de Genève, Département de Physique Théorique, Switzerland) Fagnocchi, Serena (SISSA-International School for Advanced Studies, Italy) Finazzi, Stefano (SISSA-International School for Advanced Studies, Italy) Francia, Dario (University Paris 7 - APC, France) Ghosh, Subir (Indian Statistical Institute, India) Gomberoff, Andres (Universidad Catolica de Chile, Chile) Grumiller, Daniel (Institute for Theoretical Physics Vienna University of Technology, Austria) Herrera-Aguilar, Alfredo (IFM, Universidad Michoacana de San Nicolas de Hidalgo, Mexico) Hsu, Steve (University of Oregon, USA) Ichinose, Shoichi (University of Shizuoka, SFNS, Japan) Kiefer, Claus (Institute for Theoretical Physics, University of Cologne, Germany) Kokkotas, Kostas (Theoretical Astrophysics, Eberhard Karls University of Tuebingen, Germany) Kothawala, Dawood (IUCAA, Pune

  6. List of Posters (United States)

    List of Posters: Dark matter annihilation in the Galactic galo, by Dokuchaev Vyacheslav, et al. NEMO developments towards km3 telescope in the Mediterranean Sea. The NEMO project. Neutrino Mediterranean Observatory By Antonio Capone, NEMO Collaboration. Alignment as a result from QCD jet production or new still unknown physics at LHC? By Alexander Snigirev. Small-scale fluctuations of extensive air showers: systematics in energy and muon density estimation By Grigory Rubtsov. SHINIE: Simulation of High-Energy Neutrino Interacting with the Earth By Lin Guey-Lin, et al.. Thermodynamics of rotating solutions in n+1 dimensional Einstein - Maxwell -dilation gravity By Ahmad Sheykhi, et al.. Supernova neutrino physics with future large Cherenkov detectors By Daniele Montanino. Crossing of the Cosmological Constant Barrier in the string Inspired Dark Energy Model By S. Yu. Vernov. Calculations of radio signals produced by ultra-high and extremely high energy neutrino induced cascades in Antarctic ice By D. Besson, et al.. Inflation, Cosmic Acceleration and string Gravity By Ischwaree Neupane. Neutrino Physics: Charm and J/Psi production in the atmosphere By Liudmila Volkova. Three generation flavor transitions and decays of supernova relic neutrinos By Daniele Montanino. Lattice calculations & computational quantum field theory: Sonification of Quark and Baryon Spectra By Markum Harald, et al.. Generalized Kramers-Wannier Duality for spin systems with non-commutative symmetry By V. M. Buchstaber, et al.. Heavy ion collisions & quark matter: Nuclear matter jets and multifragmentation By Danut Argintaru, et al.. QCD hard interactions: The qT-spectrum of the Higgs and Slepton-pairs at the LHC By Guiseppe Bozzi. QCD soft interactions: Nonperturbative effects in Single-Spin Asymmetries: Instantons and TMD-parton distributions By Igor Cherednikov, et al.. Gluon dominance model and high multiplicity By Elena Kokoulina. Resonances in eta pi- pi- pi+ system By Dmitry Ryabchikov

  7. PREFACE: XIV International Conference on Calorimetry in High Energy Physics (United States)

    Wang, Yifang


    (Texas Tech University), Weidong Li (IHEP) 3) Readout techniques - Gerald Eigen (University of Bergen), Zheng Wang (IHEP) 4) Operating calorimeters and calibration - Marat Gataullin (CERN), Francesco Lanni (BNL) 5) Future calorimetry - Tohru Takeshita (Shinshu University), Lei Xia (Argonne National Laboratory) 6) Astrophysics and neutrino calorimetry - Giuliana Fiorillo (INFN), Hiro Tajima (SLAC) List of Participants AKCHURIN, NuralTexas Tech University AN, ZhenghuaIHEP AUFFRAY, EtiennetteCERN BANFI, DaniloUniversità degli Studi di Milano, INFN BASHARINA-FRESHVILLE, AnastasiaUniversity College London BEAUCHEMIN, Pierre-HuguesUniversity of Oxford BENAGLIA, Andrea DavideUniversity of Milano - Bicocca and INFN BIAN, JianminIHEP BIINO, CristinaINFN BILKI, BurakUniversity of Iowa BLAHA, JanLAPP BOUDRY, VincentLLR / CNRS-IN2P3 CAI, XiaoIHEP CAPONE, AntonioPhysics Department University "La Sapienza" and INFN CAVALLARI, FrancescaCERN and INFN Rome CECCHI, ClaudiaUniversity di Perugia e INFN CHANG, JinfanIHEP CHEN, HuchengBrookhaven National Laboratory CHILDERS, TaylorUniversität Heidelberg - Kirchhoff-Institut für Physik DAO, ValerioGeneva University - DPNC DE LA TAILLE, ChristopheIN2P3/OMEGA-LAL DIEMOZ, MarcellaINFN Roma DOTTI, AndreaCERN EIGEN, GeraldUniversity of Bergen EPIFANOV, DenisBudker Institute of Nuclear Physics FAIVRE, JulienLPSC Grenoble France FANG, JianIHEP FANG, ShuangshiIHEP FANTONI, AlessandraINFN - LNF FERRI, FedericoCEA/Saclay Irfu/SPP FERRONI, FernandoSapienza University & INFN Roma FISK, Henry EugeneFermilab GABALDON, CarolinaCERN GARUTTI, ErikaDESY GAUDIO, GabriellaIstituto Nazionale di Fisica Nucleare - Sezione di Pavia GILLBERG, DagCarleton University GIOVANNINI, PaolaMax-Planck-Institut für Physik GLAZOV, AlexanderDESY GRACHOV, OlegUniversity of Kansas HAPPACHER, FabioINFN HE, MiaoIHEP HORI, YasutoUniversity of Tokyo, CNS HU, TaoIHEP HULTH, Per-OlofStockholm University JUN, Soon YungCarnegie Mellon University JURK, StefanISEG Spezialelektronik gmb

  8. EDITORIAL: Colloidal suspensions Colloidal suspensions (United States)

    Petukhov, Andrei; Kegel, Willem; van Duijneveldt, Jeroen


    N W 2002 Nature 416 811 [9] Borsboom M et al 1998 J. Synchrotron Radiat. 5 518 [10] Zernike F and Prins J A 1927 Z. Phys. 41 184 Colloidal suspensions contents How much does the core structure of a three-phase contact line contribute to the line tension near a wetting transition? J O Indekeu, K Koga and B Widom A systematic coarse-graining strategy for semi-dilute copolymer solutions: from monomers to micelles Barbara Capone, Ivan Coluzza and Jean-Pierre Hansen Structural searches using isopointal sets as generators: densest packings for binary hard sphere mixtures Toby S Hudson and Peter Harrowell The theory of delamination during drying of confined colloidal suspensions K J Wallenstein and W B Russel Electrostatics Modeling of equilibrium hollow objects stabilized by electrostatics Ethayaraja Mani, Jan Groenewold and Willem K Kegel The Donnan equilibrium: I. On the thermodynamic foundation of the Donnan equation of state A Philipse and A Vrij Colloidal rods and platelets Cholesteric order in systems of helical Yukawa rods H H Wensink and G Jackson Magnetic-field-induced nematic-nematic phase separation and droplet formation in colloidal goethite E van den Pol, A A Verhoeff, A Lupascu, M A Diaconeasa, P Davidson, I Dozov, B W M Kuipers, D M E Thies-Weesie and G J Vroege Structure of colloidal sphere-plate mixtures N Doshi, G Cinacchi, J S van Duijneveldt, T Cosgrove, S W Prescott, I Grillo, J Phipps and D I Gittins 3D structure of nematic and columnar phases of hard colloidal platelets A B G M Leferink op Reinink, J M Meijer, D Kleshchanok, D V Byelov, G J Vroege, A V Petukhov and H N W Lekkerkerker Phase behaviour of binary mixtures of diamagnetic colloidal platelets in an external magnetic field Jonathan Phillips and Matthias Schmidt Rheo-SAXS investigation of shear-thinning behaviour of very anisometric repulsive disc-like clay suspensions A M Philippe, C Baravian, M Imperor-Clerc, J De Silva, E Paineau, I Bihannic, P Davidson, F Meneau, P Levitz and L J Michot

  9. Selected Abstracts of the 19th National Congress of the Italian Society of Perinatal Medicine (Società Italiana di Medicina Perinatale, SIMP; Naples (Italy; January 19-21, 2017

    Directory of Open Access Journals (Sweden)

    --- Various Authors