WorldWideScience

Sample records for capa fina icf

  1. Caracterización de células fotovoltaicas de capa fina basadas en silicio amorfo emplendo descargas luminiscentes

    OpenAIRE

    Sánchez, Pascal

    2016-01-01

    Las células solares fotovoltaicas basadas en silicio amorfo (a-Si:H) ocupan, hoy en día, una posición destacable dentro del mercado mundial de los dispositivos fotovoltaicos de capa fina (TFSC). Sin embargo, sus bajas eficiencias (8 - 11 %) en comparación con las células de silicio cristalino (16 - 20 %) hacen prever que solamente ocupen una cuota de mercado entorno al 6 % para el año 2015. Este tipo de células se componen de una serie de capas de diversa naturaleza (p.e. metales, óxidos, sem...

  2. Caracterización óptica de capas finas de carbono amorfo hidrogenado mediante elipsometría espectroscópica

    OpenAIRE

    Pascual Miralles, Esther

    1991-01-01

    Este trabajo presenta una doble vertiente: por una parte, se ha diseñado y construido un elipsómetro espectral (visible-UV) automático que permite la caracterización óptica de materiales en volumen, en forma de capa fina y de estructuras multicapa. Los criterios para la alineación y calibración de este elipsómetro de analizador rotativo han sido establecidos y se han elaborado los programas informáticos de control y análisis de datos. Por otra parte, se ha realizado la caracterización óptica ...

  3. Detección por cromatografía de capa fina (CCF de metabolitos antinfúngicos producidos de Pseudomonas aeruginosa cepa PSS

    Directory of Open Access Journals (Sweden)

    Magdalena Lorenzo

    2006-01-01

    Full Text Available Se muestran los resultados preliminares obtenidos de la detección de extractos orgánicos de metabolitos antifúngicos de Pseudomonas aeruginosa cepa PSS por cromatografía de capa fina (CCF. Las extracciones fueron llevadas a cabo con acetato de etilo y la fase orgánica se analizó por TLC empleando el sistema de solvente cloroformo: acetona (3:1 como fase móvil. Para discernir el metabolito con actividad antifúngica se realizó un ensayo de Bioautografía utilizando el hongo Aspergillus flavus. Como resultado, se observó una mancha con Rf entre 0.70-0.80 detectada a luz ultravioleta (255 nm y revelada con vainillina que presenta actividad antifúngica, por lo que es posible de una manera preliminar detectar los metabolitos antifúngicos mediante la combinación de estos dos métodos.

  4. Obtención de estructuras calcopirita (CIGS) y kesterita (CZTS) como absorbentes para dispositivos fotovoltaicos de capa fina mediante métodos de síntesis de bajo coste

    OpenAIRE

    Martí Valls, Rafael

    2016-01-01

    La presente tesis se basa en la obtención de materiales absorbentes para dispositivos fotovoltaicos de capa fina. Los compuestos absorbentes estudiados han sido Cu(In0,7Ga0,3)Se2 (CIGS, calcopirita) y Cu2ZnSn(Se1-x,Sx)4 (CZTS, kesterita). En ella se han desarrollado diversos métodos químicos de obtención (sin vacío) como solvotermal/hidrotermal, sol-gel, hot-injection/ non-injection y co-precipitación de selenitos. Los materiales obtenidos han sido caracterizados estructuralmente, morfológica...

  5. Capas finas de ZrO2 para mejorar la resistencia química de los vidriados mates de calcio

    OpenAIRE

    Palacios, M. D.; Mestre, S; Orts, M. J.; Blasco, E.

    2012-01-01

    La resistencia al ataque químico de vidriados cerámicos susceptibles al mismo, concretamente formulados a partir de una frita mate de calcio, se ha mejorado depositando en la superficie una capa delgada de óxido de circonio. Un sol de circonio estabilizado es el precursor de la capa, el cual se deposita mediante aerografía sobre el vidriado cocido y con un tratamiento térmico suave (Tmax ≈ 400 ºC), es transformado en ZrO2 y anclado a la superficie. Los ensayos de resistencia química ...

  6. Identificación de aminoácidos libres por cromatografía de capa fina en jugo fresco de naranja (Citrus sinensis L. Osbeck variedad “Valencia”

    Directory of Open Access Journals (Sweden)

    Myrna Luisa Medina Bracamonte

    2013-12-01

    Full Text Available Con el interés de aportar al conocimiento de los aminoácidos libres en el jugo de naranja “Valencia” producido en Venezuela, se propuso aplicar cromatografía de capa fina, al jugo recién extraído de 2 lotes de naranjas “Valencia” adquiridas en mercados locales diferentes de la ciudad de Caracas. El jugo se centrifugó a 960 g (15 min-1. El sobrenadante se homogeneizó con igual volumen de etanol 95 % (v/v, por 3 s y se centrifugó a 900 g (15 min-1. Se ajustó el pH del sobrenadante a 1,7. Se pasó 30 mL del sobrenadante acondicionado a una columna de intercambio iónico de poliestireno activada en forma de H+ (6 x 1,7 cm. El volumen del eluato recogido se evaporó a 40 ºC a vacío hasta sequedad. El residuo seco se suspendió en 2,5 mL de una solución metanol:agua 50:50 (v/v a pH 1,7 y de allí se tomó una muestra de 5 μL con una micropipeta digital Calibra® 822, capacidad 2-20 μL y se aplicó sobre cromatofolios de sílica gel 60 para la cromatografía bidireccional: solvente I, cloroformo:metanol:amoníaco 25 % (v/v 40:40:20; solvente II, fenol:agua 80:20 (m/v. Hubo diferencias en el número de aminoácidos revelados e identificados entre los jugos de ambos lotes. Ambos cromatogramas coincidieron en 8 de los aminoácidos revelados: ácido aspártico, serina, alanina, valina, metionina, prolina, probablemente triptófano y/o fenilalanina y uno no identificado. En ambos predominó prolina y en ambos se identificó el ácido aspártico predominando en el lote 2 en proporción muy similar a la de prolina. El jugo del lote 2 se caracterizó por mayor índice de madurez y de nitrógeno aminoacídico que el jugo del lote 1, en donde el ácido aspártico estuvo en muy baja proporción. También se identificó metionina. Solo en el lote 1 se identificó lisina, ácido glutámico, asparagina y tirosina.

  7. Identificación de aminoácidos libres por cromatografía de capa fina en jugo fresco de naranja (Citrus sinensis L. Osbeck variedad "Valencia"

    Directory of Open Access Journals (Sweden)

    Myrna Luisa Medina Bracamonte

    2013-12-01

    Full Text Available Con el interés de aportar al conocimiento de los aminoácidos libres en el jugo de naranja "Valencia" producido en Venezuela, se propuso aplicar cromatografía de capa fina, al jugo recién extraído de 2 lotes de naranjas "Valencia" adquiridas en mercados locales diferentes de la ciudad de Caracas. El jugo se centrifugó a 960 g (15 min-1. El sobrenadante se homogeneizó con igual volumen de etanol 95 % (v/v, por 3 s y se centrifugó a 900 g (15 min-1. Se ajustó el pH del sobrenadante a 1,7. Se pasó 30 mL del sobrenadante acondicionado a una columna de intercambio iónico de poliestireno activada en forma de H+ (6 x 1,7 cm. El volumen del eluato recogido se evaporó a 40 ºC a vacío hasta sequedad. El residuo seco se suspendió en 2,5 mL de una solución metanol:agua 50:50 (v/v a pH 1,7 y de allí se tomó una muestra de 5 μL con una micropipeta digital Calibra® 822, capacidad 2-20 μL y se aplicó sobre cromatofolios de sílica gel 60 para la cromatografía bidireccional: solvente I, cloroformo:metanol:amoníaco 25 % (v/v 40:40:20; solvente II, fenol:agua 80:20 (m/v. Hubo diferencias en el número de aminoácidos revelados e identificados entre los jugos de ambos lotes. Ambos cromatogramas coincidieron en 8 de los aminoácidos revelados: ácido aspártico, serina, alanina, valina, metionina, prolina, probablemente triptófano y/o fenilalanina y uno no identificado. En ambos predominó prolina y en ambos se identificó el ácido aspártico predominando en el lote 2 en proporción muy similar a la de prolina. El jugo del lote 2 se caracterizó por mayor índice de madurez y de nitrógeno aminoacídico que el jugo del lote 1, en donde el ácido aspártico estuvo en muy baja proporción. También se identificó metionina. Solo en el lote 1 se identificó lisina, ácido glutámico, asparagina y tirosina.

  8. Clasificación de extractos etanólicos de especies de la familia Lauraceae por cromatografía en capa fina bidimensional y análisis estadísticos multivariado CCD-2D/ PCA-cluster

    Directory of Open Access Journals (Sweden)

    William A. Delgado

    2016-01-01

    Full Text Available Se caracterizaron los extractos etanólicos de hojas y cortezas de 13 especies de la familia Lauraceae mediante cromatografía en capa fina de dos dimensiones (2D-CCD.  Los datos posteriores se analizaron mediante técnicas de análisis estadístico multivariado (cluster y análisis de componentes principales (PCA. Lo anterior permitió hacer una distinción entre los extractos obtenidos de diferentes partes de la planta (hojas y cortezas. Se observó, además, que la metodología usada es capaz de diferenciar entre extractos obtenidos a partir de especies de Lauraceae y los de otras familias de plantas.

  9. The CAPA!

    CERN Multimedia

    Staff Association

    2016-01-01

    What is CAPA? The CAPA, or the Individual Cases Commission (Commission des Cas Particuliers), is responsible for assisting members of the Staff Association in their disputes with the Organization. A professional career is not always a bed of roses and, in certain situations, assistance is welcome. In practical terms, CAPA is a group of 7 to 8 delegates of the Staff Association who are at the service of their colleagues, there to give them advice, inform them of their rights and obligations, guide and accompany them, and offer them support in various procedures, in full confidentiality and free of charge. What kinds of issues are addressed by CAPA? A variety of subjects are covered, including: contractual situation: probation period – limited duration contracts (LD) and indefinite contracts (IC); career evolution: advancement, promotion, Performance Improvement Plan; administrative decisions; equal opportunities and diversity; health and security; appeal procedure and disciplinary procedure; rel...

  10. Capa fotod muuseumi

    Index Scriptorium Estoniae

    1998-01-01

    Robert Capa vend kinkis Madriidi Kuninganna Sofia Kunstikeskusele Hispaania kodusõda käsitleva kuulsa fotoseeria, mille hulgas on Robert Capa (õige nimega Endre Friedmann; 1913-1954) rahvusvaheliselt tuntuks teinud ja Hispaania kodusõja sümboliks muutunud foto 'Langenud vabatahtlik' 1936. aastast. Fotod pannakse avalikkusele välja 23. nov.

  11. Signaling by Drosophila capa neuropeptides.

    Science.gov (United States)

    Davies, Shireen-A; Cabrero, Pablo; Povsic, Manca; Johnston, Natalie R; Terhzaz, Selim; Dow, Julian A T

    2013-07-01

    The capa peptide family, originally identified in the tobacco hawk moth, Manduca sexta, is now known to be present in many insect families, with increasing publications on capa neuropeptides each year. The physiological actions of capa peptides vary depending on the insect species but capa peptides have key myomodulatory and osmoregulatory functions, depending on insect lifestyle, and life stage. Capa peptide signaling is thus critical for fluid homeostasis and survival, making study of this neuropeptide family attractive for novel routes for insect control. In Dipteran species, including the genetically tractable Drosophila melanogaster, capa peptide action is diuretic; via elevation of nitric oxide, cGMP and calcium in the principal cells of the Malpighian tubules. The identification of the capa receptor (capaR) in several insect species has shown this to be a canonical GPCR. In D. melanogaster, ligand-activated capaR activity occurs in a dose-dependent manner between 10(-6) and 10(-12)M. Lower concentrations of capa peptide do not activate capaR, either in adult or larval Malpighian tubules. Use of transgenic flies in which capaR is knocked-down in only Malpighian tubule principal cells demonstrates that capaR modulates tubule fluid secretion rates and in doing so, sets the organismal response to desiccation. Thus, capa regulates a desiccation-responsive pathway in D. melanogaster, linking its role in osmoregulation and fluid homeostasis to environmental response and survival. The conservation of capa action between some Dipteran species suggests that capa's role in desiccation tolerance may not be confined to D. melanogaster.

  12. ICF Annual Report 1997

    Energy Technology Data Exchange (ETDEWEB)

    Correll, D

    1998-06-01

    The continuing objective of Lawrence Livermore National Laboratory's (LLNL's) Inertial Confinement Fusion (ICF) Program is the demonstration of thermonuclear fusion ignition and energy gain in the laboratory and to support the nuclear weapons program in its use of ICF facilities. The underlying theme of all ICF activities as a science research and development program is the Department of Energy's (DOE's) Defense Programs (DP) science-based Stockpile Stewardship Program (SSP). The mission of the US Inertial Fusion Program is twofold: (1) to address high-energy-density physics issues for the SSP and (2) to develop a laboratory microfusion capability for defense and energy applications. In pursuit of this mission, the ICF Program has developed a state-of-the-art capability to investigate high-energy-density physics in the laboratory. The near-term goals pursued by the ICF Program in support of its mission are demonstrating fusion ignition in the laboratory and expanding the Program's capabilities in high-energy-density science. The National Ignition Facility (NIF) project is a cornerstone of this effort.

  13. Biology of the CAPA peptides in insects.

    Science.gov (United States)

    Predel, R; Wegener, C

    2006-11-01

    CAPA peptides have been isolated from a broad range of insect species as well as an arachnid, and can be grouped into the periviscerokinin and pyrokinin peptide families. In insects, CAPA peptides are the characteristic and most abundant neuropeptides in the abdominal neurohemal system. In many species, CAPA peptides exert potent myotropic effects on different muscles such as the heart. In others, including blood-sucking insects able to transmit serious diseases, CAPA peptides have strong diuretic or anti-diuretic effects and thus are potentially of medical importance. CAPA peptides undergo cell-type-specific sorting and packaging, and are the first insect neuropeptides shown to be differentially processed. In this review, we discuss the current knowledge on the structure, distribution, receptors and physiological actions of the CAPA peptides.

  14. Using the ICF in Ireland.

    LENUS (Irish Health Repository)

    Good, Anne

    2011-05-01

    This paper reflects on the use of ICF in Ireland, taking as a case study the experience of the first National Disability Survey (NDS). There were four clear effects in Ireland of using ICF as a framework for the NDS: a) that a broader range of people with disabilities was encompassed; b) that the environmental factors included from the ICF were comprehensive and policy relevant; c) that both barriers and facilitators were incorporated into the model; and d) that a focus on research ethics was encouraged. Some general conclusions regarding the benefits and limitations of ICF based on this experience are also drawn.

  15. AGULHA FINA DE MAMA E TIREOIDE

    Directory of Open Access Journals (Sweden)

    Ivone Rosini

    2014-01-01

    Full Text Available El estudio objetivó construir un protocolo de cuidados para punción aspirativa con aguja fina de mama y tiroides. Con abordaje cualitativo, tipo convergente asistencial. el estudio fue realizado en un hospital de enseñanza en el sur de Brasil, en el periodo septiembre de 2010 a abril de 2011. Participaron del estudio 88 clientes y 20 profesionales que actúan en el Servicio de Radiología. La construcción del protocolo ocurrió en tres etapas: realización de actividades educativas em sala de espera junto a los clientes para identificación de dudas y ansiedades acerca del examen, encuentros con los profesionales para evaluación y validación del protocolo y búsqueda de evidencias científicas en las fuentes de datos. La organización de lós datos ha permitido la elaboración del organigrama de atendimiento del cliente y el protocolo de cuidados, que fue organizado en actividades secuenciales incluyendo el ejecutor, actividad y justificativa científica. Los profesionales indicaron la importancia del protocolo, trayendo beneficios para la asistencia del cliente, como la agilidad, organización y humanización del atendimiento.

  16. Fundamentals of ICF Hohlraums

    Energy Technology Data Exchange (ETDEWEB)

    Rosen, M D

    2005-09-30

    On the Nova Laser at LLNL, we demonstrated many of the key elements required for assuring that the next laser, the National Ignition Facility (NIF) will drive an Inertial Confinement Fusion (ICF) target to ignition. The indirect drive (sometimes referred to as ''radiation drive'') approach converts laser light to x-rays inside a gold cylinder, which then acts as an x-ray ''oven'' (called a hohlraum) to drive the fusion capsule in its center. On Nova we've demonstrated good understanding of the temperatures reached in hohlraums and of the ways to control the uniformity with which the x-rays drive the spherical fusion capsules. In these lectures we will be reviewing the physics of these laser heated hohlraums, recent attempts at optimizing their performance, and then return to the ICF problem in particular to discuss scaling of ICF gain with scale size, and to compare indirect vs. direct drive gains. In ICF, spherical capsules containing Deuterium and Tritium (DT)--the heavy isotopes of hydrogen--are imploded, creating conditions of high temperature and density similar to those in the cores of stars required for initiating the fusion reaction. When DT fuses an alpha particle (the nucleus of a helium atom) and a neutron are created releasing large amount amounts of energy. If the surrounding fuel is sufficiently dense, the alpha particles are stopped and can heat it, allowing a self-sustaining fusion burn to propagate radially outward and a high gain fusion micro-explosion ensues. To create those conditions the outer surface of the capsule is heated (either directly by a laser or indirectly by laser produced x-rays) to cause rapid ablation and outward expansion of the capsule material. A rocket-like reaction to that outward flowing heated material leads to an inward implosion of the remaining part of the capsule shell. The pressure generated on the outside of the capsule can reach nearly 100 megabar (100 million times

  17. The CAPA Integrative Online System for College Major Exploration

    Science.gov (United States)

    Betz, Nancy E.; Borgen, Fred H.

    2010-01-01

    Career assessment has advanced on several fronts, enabling a CAPA integrative online system for exploring college majors with unprecedented precision and utility. The key inventories in the system are the CAPA Confidence Inventory (CCI), with its 6 general and 27 specific scales, and the CAPA Interest Inventory, with its 6 general and 35 specific…

  18. CAPA-peptides of praying mantids (Mantodea).

    Science.gov (United States)

    Koehler, Rene; Predel, Reinhard

    2010-03-01

    Dictyoptera which consist of cockroaches, termites, and praying mantids are among the oldest pterygote insects known. Whereas the localization and sequences of neuropeptides from a number of cockroaches are very well known, nearly nothing is known about the neuropeptides typical of praying mantids. In this study, the neuroanatomy of the median neuroendocrine system in the abdominal ventral nerve cord and the sequences of the CAPA-peptides which are expressed in the respective neuroendocrine cells were analyzed. Altogether, 40 species belonging to different families of Mantodea were included. In contrast to cockroaches, the mantids mostly express two CAPA-periviscerokinins (PVKs), only in Mantis religiosa a third PVK was identified. These PVKs are sequence-related to the PVKs of basal cockroaches (Polyphagidae). In a group of closely related Mantodea (Paramantinae), extended forms of PVK-2 were observed. As shown, these forms are possibly the result of substitutions in the N-terminal cleavage sites of the respective PVKs. No trace of a CAPA-pyrokinin was found in any of the praying mantids.

  19. ICF ETF and its engineering development requirements

    Energy Technology Data Exchange (ETDEWEB)

    Blink, J.A.; Allen, W.O.; Billman, K.

    1980-10-01

    Inertial confinement fusion driver development and ICF target physics are being intensively explored both theoretically and experimentally. However, engineering considerations of harnessing the fusion energy pulses that are an ultimate product and goal of the ICF physics program are only being addressed on a small scale. Experience with development of other new technologies indicates that engineering development time will be substantial for ICF energy converters. The authors met at Livermore in July 1980 to form an ICF Reactor Technology Working Group to address this issue. This paper outlines the current state of planning for an ICF Engineering Test Facility (ETF) and the engineering development that must precede it.

  20. Sharing Web-Based Resources Using LON-CAPA

    Science.gov (United States)

    Lucas, Mark

    2001-10-01

    It is often cumbersome to reuse or share web-based materials developed for a particular course. The LON-CAPA project based at Michigan State University is being supported by an Information Technology Research grant from the National Science Foundation (as well as other means) to investigate means of improving resource sharing and reuseability. The LON-CAPA (Learning Online Network with Computer-Assisted Personalized Approach) combines the CAPA assessment engine (homework, quizzes, exams) with a full course delivery system. The system is being piloted at Michigan State and several other institutions. The Ohio University Department of Physics and Astronomy will begin using the system beginning Winter 2002. I will discuss the basic concepts and capabilities of the LON-CAPA system. Background information on the system can be found at the URL: http://www.lon-capa.org.

  1. Computer simulation technology in inertial confinement (ICF)

    Energy Technology Data Exchange (ETDEWEB)

    Yabe, Takashi (Gunma Univ., Kiryu (Japan). Faculty of Engineering)

    1994-12-01

    Recent development of computational technologies in inertial confinement fusion (ICF) is reviewed with a special emphasis on hydrodynamic simulations. The CIP method developed for ICF simulations is one of the typical examples that are used in various fields of physics such as variety of computational fluid dynamics, astrophysics, laser applications, geophysics, and so on. (author).

  2. Insect capa neuropeptides impact desiccation and cold tolerance.

    Science.gov (United States)

    Terhzaz, Selim; Teets, Nicholas M; Cabrero, Pablo; Henderson, Louise; Ritchie, Michael G; Nachman, Ronald J; Dow, Julian A T; Denlinger, David L; Davies, Shireen-A

    2015-03-03

    The success of insects is linked to their impressive tolerance to environmental stress, but little is known about how such responses are mediated by the neuroendocrine system. Here we show that the capability (capa) neuropeptide gene is a desiccation- and cold stress-responsive gene in diverse dipteran species. Using targeted in vivo gene silencing, physiological manipulations, stress-tolerance assays, and rationally designed neuropeptide analogs, we demonstrate that the Drosophila melanogaster capa neuropeptide gene and its encoded peptides alter desiccation and cold tolerance. Knockdown of the capa gene increases desiccation tolerance but lengthens chill coma recovery time, and injection of capa peptide analogs can reverse both phenotypes. Immunohistochemical staining suggests that capa accumulates in the capa-expressing Va neurons during desiccation and nonlethal cold stress but is not released until recovery from each stress. Our results also suggest that regulation of cellular ion and water homeostasis mediated by capa peptide signaling in the insect Malpighian (renal) tubules is a key physiological mechanism during recovery from desiccation and cold stress. This work augments our understanding of how stress tolerance is mediated by neuroendocrine signaling and illustrates the use of rationally designed peptide analogs as agents for disrupting protective stress tolerance.

  3. Stability of caffeic acid phenethyl amide (CAPA) in rat plasma.

    Science.gov (United States)

    Yang, John; Kerwin, Sean M; Bowman, Phillip D; Stavchansky, Salomon

    2012-05-01

    A validated C₁₈ reverse-phase HPLC method with UV detection at 320 nm was developed and used for the stability evaluation of caffeic acid phenethyl amide (CAPA) and caffeic acid phenethyl ester (CAPE) in rat plasma. CAPA is the amide derivative of CAPE, a naturally occurring polyphenolic compound that has been found to be active in a variety of biological pathways. CAPA has been shown to protect endothelial cells against hydrogen peroxide-induced oxidative stress to a similar degree to CAPE. CAPE has been reported to be rapidly hydrolyzed in rat plasma via esterase enzymes. CAPA is expected to display a longer half-life than CAPE by avoiding hydrolysis via plasma esterases. The stability of CAPA and CAPE in rat plasma was investigated at three temperatures. The half-lives for CAPA were found to be 41.5, 10 and 0.82 h at 25, 37 and 60 °C, respectively. The half-lives for CAPE were found to be 1.95, 0.35 and 0.13 h at 4, 25 and 37 °C, respectively. The energy of activation was found to be 22.1 kcal/mol for CAPA and 14.1 kcal/mol for CAPE. A more stable compound could potentially extend the beneficial effects of CAPE.

  4. Depósito de capas de nitruro de carbono mediante ablación láser

    Directory of Open Access Journals (Sweden)

    Soto, R.

    1998-04-01

    Full Text Available The preparation of carbon nitride thin films by ablation of different target compounds (graphite, guanazole in a reactive atmosphere of ammonia with an ArF excimer laser (193 nm is reported. The films were deposited on different substrates (silicon wafers and aluminium plates and were analysed with different techniques such as profilometry, Fourier transform infrared (FTIR and energy dispersive X-ray spectroscopy (EDX. For both targets, a comparative study of the influence of the ammonia total pressure on the growth rate, composition and properties of the obtained material has been done. A gradual nitrogen incorporation in the films with increasing ammonia pressure and also the presence of nitrogen bonded to carbon in different configurations (simple, double and/or triple bonds was observed. The use of guanazole targets leads to higher efficiency in the nitrogen incorporation and in the formation of simple C-N bonds.

    Se presenta la preparación de capas finas de nitruro de carbono mediante la ablación de diferentes tipos de blancos (grafito, guanazol en una atmósfera reactiva de amoniaco utilizando un láser de excímero de ArF (193 nm. Las capas se han depositado sobre diferentes soportes (obleas de silicio y aluminio y se han analizado empleando técnicas de caracterización básicas como la espectroscopia infrarroja mediante transformada de Fourier (FTIR, espectroscopia de rayos X por dispersión de energía (EDX y perfilometría. Se ha realizado, para los dos blancos utilizados, un estudio comparativo de la influencia de la presión total de amoniaco en la velocidad de depósito, composición y propiedades del material obtenido. Se ha observado en ambos casos la progresiva incorporación de nitrógeno en las capas con el aumento de la presión de amoniaco, estando el nitrógeno enlazado al carbono en diferentes configuraciones (enlaces simples, dobles y/o triples. La utilización del blanco de guanazol se muestra más eficiente en

  5. Zonas de Brillouin de los grupos de capa

    OpenAIRE

    García Santos, Laura

    2016-01-01

    La base de datos de las zonas de Brillouin de los grupos de capa del Bilbao Crystallographic Server incluye tablas de vectores de onda y figuras que forman la base para la clasificación de las representaciones de los grupos de capa. Las propiedades de simetría de los vectores de onda se determinan por los llamados grupos del espacio recíproco y esta clasificación se compara con la que recoge el libro “Character Tables and Compatibility Relations of The Eighty Layer Groups and Seventeen Plane ...

  6. Experiments in ICF, materials science, and astrophysics

    Directory of Open Access Journals (Sweden)

    Remington Bruce A.

    2013-11-01

    Full Text Available We have been developing HED experiments on high power ICF lasers over the past two decades that span (1 the radiative hydrodynamics of ICF capsule physics; (2 the high pressure, high strain rate, solid-state dynamics relevant to novel concepts for ICF and hypervelocity impacts in space and on Earth; and (3 the shock driven turbulence of exploding stars (supernovae. These different regimes are separated by many orders of magnitude in length, time, and temperature, yet there are common threads that run through all of these phenomena, such as the occurrence of hydrodynamic instabilities. Examples from each of these three seemingly very disparate regimes are given, and the common theme of hydrodynamic instability evolution is explored.

  7. Mechanism and function of Drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor.

    NARCIS (Netherlands)

    Terhzaz, S.; Cabrero, P.; Robben, J.H.; Radford, J.C.; Hudson, B.D.; Milligan, G.; Dow, J.A.; Davies, S.A.

    2012-01-01

    The capa peptide receptor, capaR (CG14575), is a G-protein coupled receptor (GPCR) for the D. melanogaster capa neuropeptides, Drm-capa-1 and -2 (capa-1 and -2). To date, the capa peptide family constitutes the only known nitridergic peptides in insects, so the mechanisms and physiological function

  8. The ICF and Postsurgery Occupational Therapy after Traumatic Hand Injury

    Science.gov (United States)

    Fitinghoff, Helene; Lindqvist, Birgitta; Nygard, Louise; Ekholm, Jan; Schult, Marie-Louise

    2011-01-01

    Recent studies have examined the effectiveness of hand rehabilitation programmes and have linked the outcomes to the concept of ICF but not to specific ICF category codes. The objective of this study was to gain experience using ICF concepts to describe occupational therapy interventions during postsurgery hand rehabilitation, and to describe…

  9. Identification of one capa and two pyrokinin receptors from the malaria mosquito Anopheles gambiae

    DEFF Research Database (Denmark)

    Olsen, Stine S; Cazzamali, Giuseppe; Williamson, Michael

    2007-01-01

    We cloned the cDNA of three evolutionarily related G protein-coupled receptors from the malaria mosquito Anopheles gambiae and functionally expressed them in Chinese hamster ovary cells. One receptor, Ang-Capa-R, was only activated by the two Anopheles capa neuropeptides Ang-capa-1 (GPTVGLFAFPRVa...

  10. Identification and expression of capa gene in the fire ant, Solenopsis invicta.

    Science.gov (United States)

    Choi, Man-Yeon; Köhler, Rene; Vander Meer, Robert K; Neupert, Susanne; Predel, Reinhard

    2014-01-01

    Recent genome analyses suggested the absence of a number of neuropeptide genes in ants. One of the apparently missing genes was the capa gene. Capa gene expression in insects is typically associated with the neuroendocrine system of abdominal ganglia; mature CAPA peptides are known to regulate diuresis and visceral muscle contraction. The apparent absence of the capa gene raised questions about possible compensation of these functions. In this study, we re-examined this controversial issue and searched for a potentially unrecognized capa gene in the fire ant, Solenopsis invicta. We employed a combination of data mining and a traditional PCR-based strategy using degenerate primers designed from conserved amino acid sequences of insect capa genes. Our findings demonstrate that ants possess and express a capa gene. As shown by MALDI-TOF mass spectrometry, processed products of the S. invicta capa gene include three CAPA periviscerokinins and low amounts of a pyrokinin which does not have the C-terminal WFGPRLa motif typical of CAPA pyrokinins in other insects. The capa gene was found with two alternative transcripts in the CNS. Within the ventral nerve cord, two capa neurons were immunostained in abdominal neuromeres 2-5, respectively, and projected into ventrally located abdominal perisympathetic organs (PSOs), which are the major hormone release sites of abdominal ganglia. The ventral location of these PSOs is a characteristic feature and was also found in another ant, Atta sexdens.

  11. Identification and expression of capa gene in the fire ant, Solenopsis invicta.

    Directory of Open Access Journals (Sweden)

    Man-Yeon Choi

    Full Text Available Recent genome analyses suggested the absence of a number of neuropeptide genes in ants. One of the apparently missing genes was the capa gene. Capa gene expression in insects is typically associated with the neuroendocrine system of abdominal ganglia; mature CAPA peptides are known to regulate diuresis and visceral muscle contraction. The apparent absence of the capa gene raised questions about possible compensation of these functions. In this study, we re-examined this controversial issue and searched for a potentially unrecognized capa gene in the fire ant, Solenopsis invicta. We employed a combination of data mining and a traditional PCR-based strategy using degenerate primers designed from conserved amino acid sequences of insect capa genes. Our findings demonstrate that ants possess and express a capa gene. As shown by MALDI-TOF mass spectrometry, processed products of the S. invicta capa gene include three CAPA periviscerokinins and low amounts of a pyrokinin which does not have the C-terminal WFGPRLa motif typical of CAPA pyrokinins in other insects. The capa gene was found with two alternative transcripts in the CNS. Within the ventral nerve cord, two capa neurons were immunostained in abdominal neuromeres 2-5, respectively, and projected into ventrally located abdominal perisympathetic organs (PSOs, which are the major hormone release sites of abdominal ganglia. The ventral location of these PSOs is a characteristic feature and was also found in another ant, Atta sexdens.

  12. The insect capa neuropeptides impact desiccation and cold stress responses

    Science.gov (United States)

    Background: Insects are so successful because of great resistance to environmental stress, yet little is known about how such responses may be mediated by the neuroendocrine system. Results: We provide evidence that the capability (capa) neuropeptide gene and peptide are critical mediators of desic...

  13. Relationship between interRAI HC and the ICF: opportunity for operationalizing the ICF

    Directory of Open Access Journals (Sweden)

    Ljunggren Gunnar

    2009-03-01

    Full Text Available Abstract Background The International Classification of Functioning, Disability and Health (ICF is embraced as a framework to conceptualize human functioning and disability. Health professionals choose measures to represent the domains of the framework. The ICF coding classification is an administrative system but multiple studies have linked diverse clinical assessments to ICF codes. InterRAI-HC (home care is an assessment designed to assist planning of care for patients receiving home care. Examining the relationship between the ICF and the interRAI HC is of particular interest because the interRAI assessments are widely used in clinical practice and research, are computerized, and uploaded to databases that serve multiple purposes including public reporting of quality in Canada and internationally. The objective of this study was to examine the relationship between the interRAI HC (home care assessment and the ICF. Specifically, the goal was to determine the proportion of interRAI HC items that can be linked to each of the major domains of the ICF (Body Function, Body Structure, Activities and Participation, and the Environmental Factors, the chapters and the specific ICF codes. Methods Three coders who were familiar with both the home care assessment and the ICF independently assigned ICF codes to inter-RAI HC items. Subsequently, a series of teleconference meetings were held to reach consensus on the primary code and much later consensus was used to finalize codes for additional items added to the interRAI HC. Results Following exclusion of administrative and diagnostic sections, 175 interRAI items were examined for potential assignment of codes. Of these 52 were assigned codes related to body function, 43 to activities and participation, 34 to environment, 1 to body structure, 17 to not coded, and 26 to not defined. Considering all 3-digit ICF codes, interRAI items addressed 43.2% of Body Function and 50.6% of Activities and Participation

  14. Two capa-genes are expressed in the neuroendocrine system of Rhodnius prolixus.

    Science.gov (United States)

    Neupert, Susanne; Russell, William K; Russell, David H; Predel, Reinhard

    2010-03-01

    CAPA-peptides have been isolated from a broad range of insect species and are typical of the neurosecretory system of the abdominal ventral nerve cord. In Rhodnius prolixus, which is known to transmit Chagas' disease, CAPA-peptides have potent antidiuretic effects. Recently, two capa-genes were isolated from this hemipteran insect; it was the first description of the occurrence of multiple capa-genes from a single insect species. The expression of peptides from one of these capa-genes was confirmed by mass spectrometry Paluzzi (2008) [10]. In this study, the abdominal neuroendocrine system of R. prolixus was screened for the occurrence of products of the second annotated capa-gene. Single nerve preparations of abdominal segmental nerves 1-3 of R. prolixus were analyzed by MALDI-TOF mass spectrometry and the products of both capa-genes were identified by tandem mass spectrometry. The co-occurrence of the different CAPA-peptides, including CAPA-precursor peptides, in all spectra from abdominal segmental nerves 1 to 3 suggests a common expression of both capa-genes in the same neuroendocrine cells. A comparison of mass spectra obtained from abdominal segmental nerves with those of the subesophageal ganglion (SEG) revealed an obvious differential processing of the CAPA-precursors within the CNS.

  15. CAPA-gene products in the haematophagous sandfly Phlebotomus papatasi (Scopoli) - vector for leishmaniasis disease

    DEFF Research Database (Denmark)

    Predel, Reinhard; Neupert, Susanne; Russell, William K.

    2013-01-01

    class associated with the regulation of diuresis in other hematophagous insects. The CAPA-peptides identified in this study include two CAPA-PVKs, differentially processed CAPA-PK, and an additional CAPA precursor peptide. The mass spectrometric analysis of different parts of the neuroendocrine system...

  16. The D. melanogaster capa-1 neuropeptide activates renal NF-kB signaling.

    Science.gov (United States)

    Terhzaz, Selim; Overend, Gayle; Sebastian, Sujith; Dow, Julian A T; Davies, Shireen-A

    2014-03-01

    The capa peptide family exists in a very wide range of insects including species of medical, veterinary and agricultural importance. Capa peptides act via a cognate G-protein coupled receptor (capaR) and have a diuretic action on the Malpighian tubules of Dipteran and Lepidopteran species. Capa signaling is critical for fluid homeostasis and has been associated with desiccation tolerance in the fly, Drosophila melanogaster. The mode of capa signaling is highly complex, affecting calcium, nitric oxide and cyclic GMP pathways. Such complex physiological regulation by cell signaling pathways may occur ultimately for optimal organismal stress tolerance to multiple stressors. Here we show that D. melanogaster capa-1 (Drome-capa-1) acts via the Nuclear Factor kappa B (NF-kB) stress signaling network. Human PCR gene arrays of capaR-transfected Human Embryonic Kidney (HEK) 293 cells showed that Drome-capa-1 increases expression of NF-kB, NF-kB regulated genes including IL8, TNF and PTGS2, and NF-kB pathway-associated transcription factors i.e. EGR1, FOS, cJUN. Furthermore, desiccated HEK293 cells show increased EGR1, EGR3 and PTGS2 - but not IL8, expression. CapaR-transfected NF-kB reporter cells showed that Drome-capa-1 increased NF-kB promoter activity via increased calcium. In Malpighian tubules, both Drome-capa-1 stimulation and desiccation result in increased gene expression of the D. melanogaster NF-kB orthologue, Relish; as well as EGR-like stripe and klumpfuss. Drome-capa-1 also induces Relish translocation in tubule principal cells. Targeted knockdown of Relish in only tubule principal cells reduces desiccation stress tolerance of adult flies. Together, these data suggest that Drome-capa-1 acts in desiccation stress tolerance, by activating NF-kB signaling.

  17. The Fina Nagu volcanic complex: Unusual submarine arc volcanism in the rapidly deforming southern Mariana margin

    Science.gov (United States)

    Brounce, Maryjo; Kelley, Katherine A.; Stern, Robert; Martinez, Fernando; Cottrell, Elizabeth

    2016-10-01

    In the Mariana convergent margin, large arc volcanoes disappear south of Guam even though the Pacific plate continues to subduct and instead, small cones scatter on the seafloor. These small cones could form either due to decompression melting accompanying back-arc extension or flux melting, as expected for arc volcanoes, or as a result of both processes. Here, we report the major, trace, and volatile element compositions, as well as the oxidation state of Fe, in recently dredged, fresh pillow lavas from the Fina Nagu volcanic chain, an unusual alignment of small, closely spaced submarine calderas and cones southwest of Guam. We show that Fina Nagu magmas are the consequence of mantle melting due to infiltrating aqueous fluids and sediment melts sourced from the subducting Pacific plate into a depleted mantle wedge, similar in extent of melting to accepted models for arc melts. Fina Nagu magmas are not as oxidized as magmas elsewhere along the Mariana arc, suggesting that the subduction component responsible for producing arc magmas is either different or not present in the zone of melt generation for Fina Nagu, and that amphibole or serpentine mineral destabilization reactions are key in producing oxidized arc magmas. Individual Fina Nagu volcanic structures are smaller in volume than Mariana arc volcanoes, although the estimated cumulative volume of the volcanic chain is similar to nearby submarine arc volcanoes. We conclude that melt generation under the Fina Nagu chain occurs by similar mechanisms as under Mariana arc volcanoes, but that complex lithospheric deformation in the region distributes the melts among several small edifices that get younger to the northeast.

  18. Análise de um secador de ervas finas assistido por termossifões

    OpenAIRE

    2014-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Mecânica, Florianópolis, 2014. Neste trabalho propõe-se estudar a secagem de ervas finas em dois tipos diferentes de secadores assistidos por termossifões, caracterizando os fenômenos físicos observados tanto na erva como no secador. É apresentada uma revisão bibliográfica sobre o estado da arte da secagem de ervas finas, dos modelos matemáticos e correlações que des...

  19. CAPA-An integrated computer-assisted personalized assignment system

    Science.gov (United States)

    Kashy, E.; Sherrill, B. M.; Tsai, Y.; Thaler, D.; Weinshank, D.; Engelmann, M.; Morrissey, D. J.

    1993-12-01

    A new integrated computer-assisted personalized assignment (CAPA) system that creates individual assignments for each student has been developed and found to be a powerful motivator. The CAPA system allows students to enter their answers to personalized assignments directly via networked terminals, gives immediate feedback and hints (allowing challenging questions), while providing the instructor with on-line performance information. The students are encouraged to study together which is known to be an effective learning strategy, but each must still obtain his/her own correct answers. Students are allowed to re-enter solutions to the problems before the due date without penalty, thus providing students with different skills levels the opportunity and incentive to understand the material without being judged during the learning process. The features and operation of the system are described, observations on its use in an introductory general physics class are reported, and some of the highly favorable student reactions are included.

  20. CAPA-gene products in the haematophagous sandfly Phlebotomus papatasi (Scopoli)--vector for leishmaniasis disease.

    Science.gov (United States)

    Predel, Reinhard; Neupert, Susanne; Russell, William K; Hauser, Frank; Russell, David H; Li, Andrew; Nachman, Ronald J

    2013-03-01

    Sandflies (Phlebotominae, Nematocera, Diptera) are responsible for transmission of leishmaniasis and other protozoan-borne diseases in humans, and these insects depend on the regulation of water balance to cope with the sudden and enormous intake of blood over a very short time period. The sandfly inventory of neuropeptides, including those that regulate diuretic processes, is completely unknown. Direct MALDI-TOF/TOF mass spectrometric analysis of dissected ganglia of Phlebotomus papatasi, combined with a data-mining of sandfly genome 'contigs', was used to identify native CAPA-peptides, a peptide class associated with the regulation of diuresis in other hematophagous insects. The CAPA-peptides identified in this study include two CAPA-PVKs, differentially processed CAPA-PK, and an additional CAPA precursor peptide. The mass spectrometric analysis of different parts of the neuroendocrine system of the sandfly indicate that it represents the first insect which accumulates CAPA-PVKs exclusively in hormone release sites of abdominal ganglia and CAPA-PK (nearly) exclusively in the corpora cardiaca. Additionally, sandflies feature the smallest abdominal ganglia (~35 μm) where CAPA-peptides could be detected so far. The small size of the abdominal ganglia does not appear to affect the development of the median neurosecretory system as it obviously does in another comparably small insect species, Nasonia vitripennis, in which no capa-gene expression was found. Rather, immunocytochemical analyses confirm that the general architecture in sandflies appears identical to that of much larger mosquitoes.

  1. Wetted foam liquid fuel ICF target experiments

    Science.gov (United States)

    Olson, R. E.; Leeper, R. J.; Yi, S. A.; Kline, J. L.; Zylstra, A. B.; Peterson, R. R.; Shah, R.; Braun, T.; Biener, J.; Kozioziemski, B. J.; Sater, J. D.; Biener, M. M.; Hamza, A. V.; Nikroo, A.; Berzak Hopkins, L.; Ho, D.; LePape, S.; Meezan, N. B.

    2016-05-01

    We are developing a new NIF experimental platform that employs wetted foam liquid fuel layer ICF capsules. We will use the liquid fuel layer capsules in a NIF sub-scale experimental campaign to explore the relationship between hot spot convergence ratio (CR) and the predictability of hot spot formation. DT liquid layer ICF capsules allow for flexibility in hot spot CR via the adjustment of the initial cryogenic capsule temperature and, hence, DT vapor density. Our hypothesis is that the predictive capability of hot spot formation is robust and 1D-like for a relatively low CR hot spot (CR∼15), but will become less reliable as hot spot CR is increased to CR>20. Simulations indicate that backing off on hot spot CR is an excellent way to reduce capsule instability growth and to improve robustness to low-mode x-ray flux asymmetries. In the initial experiments, we will test our hypothesis by measuring hot spot size, neutron yield, ion temperature, and burn width to infer hot spot pressure and compare to predictions for implosions with hot spot CR's in the range of 12 to 25. Larger scale experiments are also being designed, and we will advance from sub-scale to full-scale NIF experiments to determine if 1D-like behavior at low CR is retained as the scale-size is increased. The long-term objective is to develop a liquid fuel layer ICF capsule platform with robust thermonuclear burn, modest CR, and significant α-heating with burn propagation.

  2. Caracterização molecular de uma progênie de tangerineira 'Clementina Fina' e 'Montenegrina' Molecular characterization of a progeny between tangerines 'Clementina Fina' and 'Montenegrina'

    Directory of Open Access Journals (Sweden)

    Roberto Luis Weiler

    2010-07-01

    Full Text Available Os citros apresentam uma taxonomia muito complexa, principalmente com relação ao número de espécies que constituem o gênero Citrus e os gêneros afins. Genótipos classificados como espécies podem ter sido originados por hibridação interespecífica e preservados por meio da embrionia nucelar. O presente trabalho teve como objetivo caracterizar uma população de tangerineiras híbridas oriundas do cruzamento das tangerineiras 'Clementina Fina' (Citrus clementina Hort. ex Tan., genitor feminino, e 'Montenegrina' (Citrus deliciosa Ten., genitor masculino, utilizando marcadores do tipo microssatélites (SSR. Com 12 pares de primers, foi possível diferenciar 93 acessos do estudo e agrupar a F1 em indivíduos mais próximos do genitor feminino e do genitor masculino. O PIC (Conteúdo de Informação de Polimorfismo dos primers variou de 0,27 a 0,65. Toda a progênie do cruzamento entre 'Clementina Fina' e 'Montenegrina' analisada neste estudo é híbrida, e os SSRs foram eficientes para identificar híbridos com maior similaridade genética em relação aos genitores, mostrando a existência de variabilidade genética entre as plantas da população estudada.Citrus have a very complex taxonomy, especially considering the number of species included in genus Citrus and related genera. What is classified as a species may have originated by interespecific hybridization and preserved through nucellar embryony. This research aimed to characterize a population of hybrid tangerines, originated from the cross of 'Clementina Fina' (Citrus clementina Hort. ex Tan. as female and 'Montenegrina' (Citrus deliciosa Ten. as male parents, using microsatellite molecular makers. With 12 pairs of primers it was possible to differentiate 93 of the studied accessions and to group F1 individuals nearer to the male or to the female parent. The primers PIC (Polymorphism Information Content ranged from 0.27 to 0.65. All the analyzed progeny between 'Clementina Fina

  3. Conservation of capa peptide-induced nitric oxide signalling in Diptera.

    Science.gov (United States)

    Pollock, Valerie P; McGettigan, James; Cabrero, Pablo; Maudlin, Ian M; Dow, Julian A T; Davies, Shireen-A

    2004-11-01

    In D. melanogaster Malpighian (renal) tubules, the capa peptides stimulate production of nitric oxide (NO) and guanosine 3', 5'-cyclic monophosphate (cGMP), resulting in increased fluid transport. The roles of NO synthase (NOS), NO and cGMP in capa peptide signalling were tested in several other insect species of medical relevance within the Diptera (Aedes aegypti, Anopheles stephensi and Glossina morsitans) and in one orthopteran out-group, Schistocerca gregaria. NOS immunoreactivity was detectable by immunocytochemistry in tubules from all species studied. D. melanogaster, A. aegypti and A. stephensi express NOS in only principal cells, whereas G. morsitans and S. gregaria show more general NOS expression in the tubule. Measurement of associated NOS activity (NADPH diaphorase) shows that both D. melanogaster capa-1 and the two capa peptides encoded in the A. gambiae genome, QGLVPFPRVamide (AngCAPA-QGL) and GPTVGLFAFPRVamide (AngCAPA-GPT), all stimulate NOS activity in D. melanogaster, A. aegypti, A. stephensi and G. morsitans tubules but not in S. gregaria. Furthermore, capa-stimulated NOS activity in all the Diptera was inhibited by the NOS inhibitor l-NAME. All capa peptides stimulate an increase in cGMP content across the dipteran species, but not in the orthopteran S. gregaria. Similarly, all capa peptides tested stimulate fluid secretion in D. melanogaster, A. aegypti, A. stephensi and G. morsitans tubules but are either without effect or are inhibitory on S. gregaria. Consistent with these results, the Drosophila capa receptor was shown to be expressed in Drosophila tubules, and its closest Anopheles homologue was shown to be expressed in Anopheles tubules. Thus, we provide the first demonstration of physiological roles for two putative A. gambiae neuropeptides. We also demonstrate neuropeptide modulation of fluid secretion in tsetse tubule for the first time. Finally, we show the generality of capa peptide action, to stimulate NO/cGMP signalling and

  4. Plasma Viscosity with Mass Transport in Spherical ICF Implosion Simulations

    CERN Document Server

    Vold, Erik L; Ortega, Mario I; Moll, Ryan; Fenn, Daniel; Molvig, Kim

    2015-01-01

    The effects of viscosity and small-scale atomic-level mixing on plasmas in inertial confinement fusion (ICF) currently represent challenges in ICF research. Many current ICF hydrodynamic codes ignore the effects of viscosity though recent research indicates viscosity and mixing by classical transport processes may have a substantial impact on implosion dynamics. We have implemented a Lagrange hydrodynamic code in one-dimensional spherical geometry with plasma viscosity and mass transport and including a three temperature model for ions, electrons, and radiation treated in a gray radiation diffusion approximation. The code is used to study ICF implosion differences with and without plasma viscosity and to determine the impacts of viscosity on temperature histories and neutron yield. It was found that plasma viscosity has substantial impacts on ICF shock dynamics characterized by shock burn timing, maximum burn temperatures, convergence ratio, and time history of neutron production rates. Plasma viscosity reduc...

  5. The physics of radiation driven ICF hohlraums

    Energy Technology Data Exchange (ETDEWEB)

    Rosen, M.D.

    1995-08-07

    On the Nova Laser at LLNL, we have recently demonstrated many of the key elements required for assuring that the next proposed laser, the National Ignition Facility (NIF) will drive an Inertial Confinement Fusion (ICF) target to ignition. The target uses the recently declassified indirect drive (sometimes referred to as {open_quotes}radiation drive{close_quotes}) approach which converts laser light to x-rays inside a gold cylinder, which then acts as an x-ray {open_quotes}oven{close_quotes} (called a hohlraum) to drive the fusion capsule in its center. On Nova we`ve demonstrated good understanding of the temperatures reached in hohlraums and of the ways to control the uniformity with which the x-rays drive the spherical fusion capsules. In this lecture we briefly review the fundamentals of ICF, and describe the capsule implosion symmetry advantages of the hohlraum approach. We then concentrate on a quantitative understanding of the scaling of radiation drive with hohlraum size and wall material, and with laser pulse length and power. We demonstrate that coupling efficiency of x-ray drive to the capsule increases as we proceed from Nova to the NIF and eventually to a reactor, thus increasing the gain of the system.

  6. CAPA (Computer-Assisted Personalized Assignments) in a large university setting

    Science.gov (United States)

    Pascarella, Andrea M.

    A systematic study of the online homework system CAPA (Computer-Assisted Personalized Assignments) was carried out in the calculus-based introductory physics course at the University of Colorado, Boulder during the fall 2001 semester (N ≈ 500). This study looked at the effects CAPA had on student learning and attitudes. The students in this class were split into two groups. One group was initially assigned to CAPA; the other group was assigned to traditional homework. At mid-semester the groups switched identities (the students who began the course using CAPA had to complete traditional homework). Exam scores and Force and Motion Concept Evaluation gains showed no statistically significant differences between the groups. Written quizzes and exams were collected from a smaller sample of students and analyzed using a problem-solving rubric. No statistically significant differences in the problem solving abilities of the groups were seen. Student opinions about the effect each homework type had on their learning were elicited. Students with non-expert-like epistemologies felt that CAPA was a better learning tool while students with expert-like epistemologies believed that traditional homework was a better learning tool. Problem solving interviews were conducted weekly with 9 students. From the analysis of this data a problem solving characterization of students using CAPA and traditional homework was inferred. Four types of problems solvers emerged---the CAPA Thinker, Traditional Thinker, CAPA Guesser, and Traditional Guesser. Thinkers tend to have expert-like epistemological beliefs. Guessers generally have non-expert-like epistemologies. On quantitative problems traditional homework promoted metacognitive processes in the Traditional Thinker and CAPA hindered self-evaluation among CAPA Thinkers. On qualitative problems, the opposite was observed to occur. When the students switched homework types at mid-semester it was expected that CAPA Thinkers would become

  7. Identification of candidate categories of the International Classification of Functioning Disability and Health (ICF for a Generic ICF Core Set based on regression modelling

    Directory of Open Access Journals (Sweden)

    Üstün Bedirhan T

    2006-07-01

    Full Text Available Abstract Background The International Classification of Functioning, Disability and Health (ICF is the framework developed by WHO to describe functioning and disability at both the individual and population levels. While condition-specific ICF Core Sets are useful, a Generic ICF Core Set is needed to describe and compare problems in functioning across health conditions. Methods The aims of the multi-centre, cross-sectional study presented here were: a to propose a method to select ICF categories when a large amount of ICF-based data have to be handled, and b to identify candidate ICF categories for a Generic ICF Core Set by examining their explanatory power in relation to item one of the SF-36. The data were collected from 1039 patients using the ICF checklist, the SF-36 and a Comorbidity Questionnaire. ICF categories to be entered in an initial regression model were selected following systematic steps in accordance with the ICF structure. Based on an initial regression model, additional models were designed by systematically substituting the ICF categories included in it with ICF categories with which they were highly correlated. Results Fourteen different regression models were performed. The variance the performed models account for ranged from 22.27% to 24.0%. The ICF category that explained the highest amount of variance in all the models was sensation of pain. In total, thirteen candidate ICF categories for a Generic ICF Core Set were proposed. Conclusion The selection strategy based on the ICF structure and the examination of the best possible alternative models does not provide a final answer about which ICF categories must be considered, but leads to a selection of suitable candidates which needs further consideration and comparison with the results of other selection strategies in developing a Generic ICF Core Set.

  8. Experiments in ICF, materials science, and astrophysics

    Science.gov (United States)

    Remington, Bruce A.

    2016-10-01

    We have been developing RED experiments on high power TCF lasers over the past two decades that span (1) the radiative hydrodynamics of TCF capsule physics; (2) the high pressure, high strain rate, solid-state dynamics relevant to novel concepts for ICF and hypervelocity impacts in space and on Earth; and (3) the shock driven turbulence of exploding stars (supernovae). These different regimes are separated by many orders of magnitude in length, time, and temperature, yet there are common threads that run through all of these phenomena, such as the occurrence of hydrodynamic instabilities. Examples from each of these three seemingly very disparate regimes are given, and the common theme of hydrodynamic instability evolution is explored.

  9. Caracterización de capas coloreadas sobre AISI 304

    Directory of Open Access Journals (Sweden)

    López, J.

    1998-05-01

    Full Text Available A common method for obtaining colour coatings on stainless steel surfaces is by dipping in strongly oxidizing solutions (H2SO4-CrO3 at 70°C. This work improves the knowledge of these coatings by means of techniques that were not available some years ago, such as ellipsometry, to determine the refraction index and the thickness, and atomic field microscopy (AFM, to observe the coloured surface. From these techniques, it is possible to state that films are formed by an aggregation of particle ranging in size from 5 to 15 nm, the interstices are pores of approximately 5 nm diameter.

    El método más usual de obtener en la superficie de los aceros inoxidables capas de colores variables es mediante su inmersión en soluciones fuertemente oxidantes (H2SO4-CrO3 a una temperatura en torno a 70°C. El trabajo mejora el conocimiento que de estas capas se tiene por medio de técnicas que no eran disponibles hace algunos años, tales como la elipsometría, para la obtención de parámetros ópticos y determinación de espesores, y la microscopía de campo atómico, para la observación de la superficie coloreada. El uso conjunto de estas técnicas permite observar que la película de color está formada por una agregación de partículas con un tamaño que oscila entre los 5 y los 15 nm, los intersticios que aparecen entre las partículas pueden identificarse como poros de unos 5 nm de tamaño.

  10. ICF gamma-ray reaction history diagnostics

    Science.gov (United States)

    Herrmann, H. W.; Young, C. S.; Mack, J. M.; Kim, Y. H.; McEvoy, A.; Evans, S.; Sedillo, T.; Batha, S.; Schmitt, M.; Wilson, D. C.; Langenbrunner, J. R.; Malone, R.; Kaufman, M. I.; Cox, B. C.; Frogget, B.; Miller, E. K.; Ali, Z. A.; Tunnell, T. W.; Stoeffl, W.; Horsfield, C. J.; Rubery, M.

    2010-08-01

    Reaction history measurements, such as nuclear bang time and burn width, are fundamental components of diagnosing ICF implosions and will be employed to help steer the National Ignition Facility (NIF) towards ignition. Fusion gammas provide a direct measure of nuclear interaction rate (unlike x-rays) without being compromised by Doppler spreading (unlike neutrons). Gas Cherenkov Detectors that convert fusion gamma rays to UV/visible Cherenkov photons for collection by fast optical recording systems have established their usefulness in illuminating ICF physics in several experimental campaigns at OMEGA. In particular, bang time precision better than 25 ps has been demonstrated, well below the 50 ps accuracy requirement defined by the NIF. NIF Gamma Reaction History (GRH) diagnostics are being developed based on optimization of sensitivity, bandwidth, dynamic range, cost, and NIF-specific logistics, requirements and extreme radiation environment. Implementation will occur in two phases. The first phase consists of four channels mounted to the outside of the target chamber at ~6 m from target chamber center (GRH-6m) coupled to ultra-fast photo-multiplier tubes (PMT). This system is intended to operate in the 1013-1017 neutron yield range expected during the early THD campaign. It will have high enough bandwidth to provide accurate bang times and burn widths for the expected THD reaction histories (> 80 ps fwhm). Successful operation of the first GRH-6m channel has been demonstrated at OMEGA, allowing a verification of instrument sensitivity, timing and EMI/background suppression. The second phase will consist of several channels located just inside the target bay shield wall at 15 m from target chamber center (GRH-15m) with optical paths leading through the cement shield wall to well-shielded streak cameras and PMTs. This system is intended to operate in the 1016-1020 yield range expected during the DT ignition campaign, providing higher temporal resolution for the

  11. ICF Program: LDRD-ER Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Glenzer, S H

    2004-02-05

    In the 01-ERD-107 LDRD-ER project, we have performed novel Thomson scattering experiments at the Trident and Omega laser facilities and provided high quality spectral data. These results have led to the development of the first quantitative understanding of laser-plasma interactions for NIF plasmas. For this purpose an green/ultraviolet probe laser, built for Nova in 1998 [1] and successfully used to measure both temperature and plasma wave amplitudes [2], has been deployed on Omega. The Thomson scattering diagnostics has been used twofold: (1) it provided independent measurements of the plasma electron and ion temperature, the plasma flow velocity, or the electron distribution function; (2) it provided measurements of the primary plasma wave and their secondary non-linear decay wave products. These experiments at Omega provide definitive quantitative results on the nonlinear saturation of stimulated Raman scattering for green (2{omega}) beams. In addition, the experiments on the Trident laser have led to a quantitative understanding of the stimulated Brillouin scattering in low-Z plasmas. A nonlinear frequency detuning model has successfully explained all the experimental observable including the SBS reflectivity. This model has been implemented into the laser-plasma interaction code pF3D as a tool to design and optimize NIF target experiments with SBS and SRS losses included. The development of quantitative models for SBS and SRS for various regimes has now been adopted as part of the WBS1 project within the ICF program.

  12. Web Based Homework for CAPA in General Education Astronomy Courses

    Science.gov (United States)

    Robertson, T. H.

    2002-12-01

    Qualitative questions in astronomy have been developed to operate under the CAPA web-based homework system. Multiple versions of similar questions and software randomization are used to create different homework sets for each student. The questions are grouped by concept and subject to create more challenging activities from relatively simple questions. These questions have been used for three semesters in five sections of ASTRO 100 which enrolled a total of 500 students over the past two years. Student surveys consistently indicate that they like the system and believe that it helps them to learn. Cognitive measures in the form of exam and course grades do not demonstrate statistically significant improvement in sections which have used the new homework system. This is due in part to a conscious effort to create exam questions which focus on content understanding and not memorization and the persistent student habit of studying for exams by memorizing homework. Differences have been identified between female and male students in terms of completion rates and performance on homework, quiz and exam scores. This work was supported in part by funding from the George and Frances Ball Fund for Academic Excellence and the 21st Century Fund for Faculty Development.

  13. Identification and characterization of pyrokinin and CAPA peptides, and corresponding GPCRs from spotted wing drosophila, Drosophila suzukii.

    Science.gov (United States)

    Choi, Man-Yeon; Ahn, Seung-Joon; Kim, A Young; Koh, Youngho

    2017-01-07

    The family of FXPRLamide peptides serves as a major insect hormone. It is characterized by a core active amino acid sequence conserved at the C-terminal ends, and provides various physiological roles across the Insecta. In this study we identified and characterized pyrokinin (PK) and CAPA cDNAs encoding two FXPRLamide peptides, pyrokinin and CAPA-DH (diapause hormone), and two corresponding G protein-coupled receptors (GPCRs) from spotted wing drosophila (SWD), Drosophila suzukii. Expressions of PK and CAPA mRNAs were differentially observed during all life stages except the embryo, and the detection of CAPA transcription was relatively strong compared with the PK gene in SWD. Both D. suzukii pyrokinin receptor (DrosuPKr) and CAPA-DH receptor (DrosuCAPA-DHr) were functionally expressed and confirmed through binding to PK and DH peptides. Differential expression of two GPCRs occurred during all life stages; a strong transcription of DrosuPKr was observed in the 3rd instar. DrosuCAPA-DHr was clearly expressed from the embryo to the larva, but not detected in the adult. Gene regulation during the life stages was not synchronized between ligand and receptor. For example, SWD CAPA mRNA has been up-regulated in the adult while CAPA-DHr was down-regulated. The difference could be from the CAPA mRNA translating multiple peptides including CAPA-DH and two CAPA-PVK (periviscerokinin) peptides to act on different receptors. Comparing the genes of SWD PK, CAPA, PKr and CAPA-DHr to four corresponding genes of D. melanogaster, SWD CAPA and the receptor are more similar to D. melanogaster than PK and the receptor. These data suggest that the CAPA gene could be evolutionally more conserved to have a common biological role in insects. In addition, the effect of Kozak sequences was investigated by the expression of the GPCRs with or without Kozak sequences in Sf9 insect cells. The Kozak sequenced PK receptor was significantly less active than the original (= no Kozak sequenced

  14. Identification of one capa and two pyrokinin receptors from the malaria mosquito Anopheles gambiae.

    Science.gov (United States)

    Olsen, Stine S; Cazzamali, Giuseppe; Williamson, Michael; Grimmelikhuijzen, Cornelis J P; Hauser, Frank

    2007-10-19

    We cloned the cDNA of three evolutionarily related G protein-coupled receptors from the malaria mosquito Anopheles gambiae and functionally expressed them in Chinese hamster ovary cells. One receptor, Ang-Capa-R, was only activated by the two Anopheles capa neuropeptides Ang-capa-1 (GPTVGLFAFPRVamide) and Ang-capa-2 (pQGLVPFPRVamide) with EC(50) values of 8.6x10(-9)M and 3.3x10(-9)M, respectively, but not by any other known mosquito neuropeptide. The second receptor, Ang-PK-1-R, was selectively activated by the Anopheles pyrokinin-1 peptides Ang-PK-1-1 (AGGTGANSAMWFGPRLamide) and Ang-PK-1-2 (AAAMWFGPRLamide) with EC(50) values of 3.3x10(-8)M and 2.5x10(-8)M, respectively, but not by mosquito capa or pyrokinin-2 peptides. For the third receptor, Ang-PK-2-R, the most potent ligands were the pyrokinin-2 peptides Ang-PK-2-1 (DSVGENHQRPPFAPRLamide) and Ang-PK-2-2 (NLPFSPRLamide) with EC(50) values of 5.2x10(-9)M and 6.4x10(-9)M, respectively. However, this receptor could also be activated by the two pyrokinins-1, albeit with lower potency (EC(50): 2-5x10(-8)M). Because Ang-capa-1 and -2 and Ang-PK-1-1 are located on one preprohormone and the other peptides on another prohormone, these results imply a considerable crosstalk between the capa, pyrokinin-1 and pyrokinin-2 systems. Gene structure and phylogenetic tree analyses showed that Ang-Capa-R was the orthologue of the Drosophila capa receptor CG14575, Ang-PK-1-R the orthologue of the Drosophila pyrokinin-1 receptor CG9918, and Ang-PK-2-R the orthologue of the Drosophila pyrokinin-2 receptors CG8784 and CG8795. This is the first report on the functional characterization and crosstalk properties of capa and pyrokinin receptors in mosquitoes.

  15. The Nova Upgrade Facility for ICF ignition and gain

    Science.gov (United States)

    Lowdermilk, W. H.; Campbell, E. M.; Hunt, J. T.; Murray, J. R.; Storm, E.; Tobin, M. T.; Trenholme, J. B.

    1992-01-01

    Research on Inertial Confinement Fusion (ICF) is motivated by its potential defense and civilian applications, including ultimately the generation of electric power. The U.S. ICF Program was reviewed recently by the National Academy of Science (NAS) and the Fusion Policy Advisory Committee (FPAC). Both committees issued final reports in 1991 which recommended that first priority in the ICF program be placed on demonstrating fusion ignition and modest gain (G less than 10). The U.S. Department of Energy and Lawrence Livermore National Laboratory (LLNL) have proposed an upgrade of the existing Nova Laser Facility at LLNL to accomplish these goals. Both the NAS and FPAC have endorsed the upgrade of Nova as the optimal path to achieving ignition and gain. Results from Nova Upgrade Experiments will be used to define requirements for driver and target technology both for future high-yield military applications, such as the Laboratory Microfusion Facility (LMF) proposed by the Department of Energy, and for high-gain energy applications leading to an ICF engineering test facility. The central role and modifications which Nova Upgrade would play in the national ICF strategy are described.

  16. Mechanism and function of Drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor.

    Directory of Open Access Journals (Sweden)

    Selim Terhzaz

    Full Text Available The capa peptide receptor, capaR (CG14575, is a G-protein coupled receptor (GPCR for the D. melanogaster capa neuropeptides, Drm-capa-1 and -2 (capa-1 and -2. To date, the capa peptide family constitutes the only known nitridergic peptides in insects, so the mechanisms and physiological function of ligand-receptor signalling of this peptide family are of interest. Capa peptide induces calcium signaling via capaR with EC₅₀ values for capa-1 = 3.06 nM and capa-2 = 4.32 nM. capaR undergoes rapid desensitization, with internalization via a b-arrestin-2 mediated mechanism but is rapidly re-sensitized in the absence of capa-1. Drosophila capa peptides have a C-terminal -FPRXamide motif and insect-PRXamide peptides are evolutionarily related to vertebrate peptide neuromedinU (NMU. Potential agonist effects of human NMU-25 and the insect -PRLamides [Drosophila pyrokinins Drm-PK-1 (capa-3, Drm-PK-2 and hugin-gamma [hugg

  17. Mechanism and function of Drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor.

    Science.gov (United States)

    Terhzaz, Selim; Cabrero, Pablo; Robben, Joris H; Radford, Jonathan C; Hudson, Brian D; Milligan, Graeme; Dow, Julian A T; Davies, Shireen-A

    2012-01-01

    The capa peptide receptor, capaR (CG14575), is a G-protein coupled receptor (GPCR) for the D. melanogaster capa neuropeptides, Drm-capa-1 and -2 (capa-1 and -2). To date, the capa peptide family constitutes the only known nitridergic peptides in insects, so the mechanisms and physiological function of ligand-receptor signalling of this peptide family are of interest. Capa peptide induces calcium signaling via capaR with EC₅₀ values for capa-1 = 3.06 nM and capa-2 = 4.32 nM. capaR undergoes rapid desensitization, with internalization via a b-arrestin-2 mediated mechanism but is rapidly re-sensitized in the absence of capa-1. Drosophila capa peptides have a C-terminal -FPRXamide motif and insect-PRXamide peptides are evolutionarily related to vertebrate peptide neuromedinU (NMU). Potential agonist effects of human NMU-25 and the insect -PRLamides [Drosophila pyrokinins Drm-PK-1 (capa-3), Drm-PK-2 and hugin-gamma [hugg

  18. Heterogeneous clinical presentation in ICF syndrome: correlation with underlying gene defects.

    NARCIS (Netherlands)

    Weemaes, C.M.R.; Tol, M.J. van; Wang, J.; Ostaijen-ten Dam, M.M. van; Eggermond, M.C. van; Thijssen, P.E.; Aytekin, C.; Brunetti-Pierri, N.; Burg, M. van der; aham Davies, E. Gr; Ferster, A.; Furthner, D.; Gimelli, G.; Gennery, A.; Kloeckener-Gruissem, B.; Meyn, S.; Powell, C.; Reisli, I.; Schuetz, C.; Schulz, A.; Shugar, A.; Elsen, P.J. van den; Maarel, S.M. van der

    2013-01-01

    Immunodeficiency with centromeric instability and facial anomalies (ICF) syndrome is a primary immunodeficiency, predominantly characterized by agammaglobulinemia or hypoimmunoglobulinemia, centromere instability and facial anomalies. Mutations in two genes have been discovered to cause ICF syndrome

  19. Identification of two capa cDNA transcripts and detailed peptidomic characterization of their peptide products in Periplaneta americana

    Directory of Open Access Journals (Sweden)

    Susanne Neupert

    2014-06-01

    Full Text Available The first CAPA peptides of insects were identified from Periplaneta americana using extracts of 8000 abdominal perisympathetic organs. The corresponding gene of cockroaches and other basal insects, however, remained undiscovered. Here we identified two capa cDNA transcripts of P. americana. Single cell mass spectrometry of capa neurons in abdominal ganglia yielded a complete coverage of the precursor sequences of both transcripts; with intermediates of precursor processing more prominent in somata than in perisympathetic organs. The processing of the CAPA precursor in P. americana is compared with that in the beetle Tribolium castaneum which was re-evaluated in this study.

  20. Classification of functioning and impairment: the development of ICF core sets for autism spectrum disorder.

    Science.gov (United States)

    Bölte, Sven; de Schipper, Elles; Robison, John E; Wong, Virginia C N; Selb, Melissa; Singhal, Nidhi; de Vries, Petrus J; Zwaigenbaum, Lonnie

    2014-02-01

    Given the variability seen in Autism Spectrum Disorder (ASD), accurate quantification of functioning is vital to studying outcome and quality of life in affected individuals. The International Classification of Functioning, Disability and Health (ICF) provides a comprehensive, universally accepted framework for the description of health-related functioning. ICF Core Sets are shortlists of ICF categories that are selected to capture those aspects of functioning that are most relevant when describing a person with a specific condition. In this paper, the authors preview the process for developing ICF Core Sets for ASD, a collaboration with the World Health Organization and the ICF Research Branch. The ICF Children and Youth version (ICF-CY) was derived from the ICF and designed to capture the specific situation of the developing child. As ASD affects individuals throughout the life span, and the ICF-CY includes all ICF categories, the ICF-CY will be used in this project ("ICF(-CY)" from now on). The ICF(-CY) categories to be included in the ICF Core Sets for ASD will be determined at an ICF Core Set Consensus Conference, where evidence from four preparatory studies (a systematic review, an expert survey, a patient and caregiver qualitative study, and a clinical cross-sectional study) will be integrated. Comprehensive and Brief ICF Core Sets for ASD will be developed with the goal of providing useful standards for research and clinical practice and generating a common language for functioning and impairment in ASD in different areas of life and across the life span.

  1. Biopsia de la próstata, aspiración con aguja fina

    OpenAIRE

    Gómez Lloreda, Eugenio; Chavarro Porras, Jorge; Martínez Garzón, Miguel

    2012-01-01

    Se presentan los resultados preliminares de biopsia por punción con aguja tina de la próstata en cuanto a su tolerancia por parte de los pacientes, su fácil manejo por parte del urólogo y su interpretación desde el punto de vista histopatológico. Los resultados comparativos entre la biopsia por punción con aguja fina y la biopsia con Tru-Cut son similares en cuanto a la certeza en el diagnóstico del cáncer de próstata, pero las complicaciones médicas son mucho menores en la biopsia por punció...

  2. 42 CFR 431.154 - Informal reconsideration for ICFs/MR.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Informal reconsideration for ICFs/MR. 431.154... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE ORGANIZATION AND GENERAL ADMINISTRATION Appeals Process for NFs and ICFs/MR § 431.154 Informal reconsideration for ICFs/MR. The informal...

  3. Validation and factorial invariance of children's attraction to physical activity (CAPA) scale in Portugal.

    Science.gov (United States)

    Seabra, Ana C; Malina, Robert M; Parker, Melissa; Seabra, André; Brustad, Robert; Maia, José A; Fonseca, António M

    2014-01-01

    The Children's Attraction to Physical Activity (CAPA) scale assesses interest in and attraction to the physical activity (PA) of children of elementary school age. The original (25 items) and shorter versions (15 items) of the scale were developed and validated with American children. The purpose of this study was to cross-validate the shorter version of the CAPA scale for use with Portuguese schoolchildren and to examine the invariance of the multidimensional factor structure of the scale in two samples. The sample comprised 683 children (7-10 years) from public primary schools. The sample was divided into calibration and cross-validation samples. The scale was translated into Portuguese and underwent forward translation, synthesis of the translation and backward translation and was then subjected to expert committee review, pretest and reliability assessment. Internal consistency for each of the five subscales within the a priori 5-factor structure of the CAPA scale was evaluated through Cronbach's alpha, followed by a series of confirmatory factor analyses (CFAs) for both the calibration and cross-validation samples. The maximum likelihood robust estimation method was used. The CFA demonstrated that a 5-factor structural model of the Portuguese translation of the CAPA scale was invariant. The construct analysed had the same basic meaning and structural and item differences within the two samples. The results indicated that the CAPA scale is appropriate for use with Portuguese schoolchildren. The availability of a valid and reliable scale should enhance opportunities for further understanding of children's involvement in PA.

  4. (Rubiaceae A PARTIR DE CAPAS DELGADAS DE CÉLULAS

    Directory of Open Access Journals (Sweden)

    Catalina BOTERO GIRALDO

    2015-01-01

    Full Text Available Conociendo las propiedades medicinales de la especie vegetal Psychotria ipecacuanha (Brot. Stokes, su crítico estado de conservación, así como las dificultades que presenta para la propagación efectiva, el presente estudio tuvo como objetivo evaluar su potencial de propagación por los sistemas de regeneración in vitro , organogénesis y embriogénesis somática. Para este propósito, capas delgadas de células (CDCs de tallos y de hojas, así como segmentos foliares fueron sometidos a diferentes tratamientos con reguladores de crecimiento y condiciones de luz. Además se estableció el efecto de diferentes longitudes de onda vía diodos emisores de luz (LEDs, sobre la regeneración en estos explantes y nudos provenientes de plantas in vitro . Los resultados obtenidos mostraron que los segmentos de hoja y las CDCs de tallo sembrados en el medio de cultivo MS suplementado con las combinaciones de los reguladores de crecimiento IBA + BAP e IBA + TDZ formaron embriones somáticos y brotes. Los cortes histológicos realizados corroboraron estos dos tipos de origen. Se encontró que bajo la condición lumínica 16/8, se alcanzaron los mejores resultados de inducción de brotes y embriones. En cuanto al efecto de las diferentes longitudes de onda de luz, se encontró que las correspondientes al rojo, verde y blanca, favorecieron el crecimiento y desarrollo de brotes y la inducción de embriones somáticos. El desarrollo de los brotes a partir de los nudos no presentó diferencias estadísticas entre los tratamientos con LEDs, por lo que se recomienda el uso de la luz blanca continua y con fotoperiodo durante el proceso de multiplicación y desarrollo de éstos.

  5. Molecular cloning and functional expression of a Drosophila receptor for the neuropeptides capa-1 and -2.

    Science.gov (United States)

    Iversen, Annette; Cazzamali, Giuseppe; Williamson, Michael; Hauser, Frank; Grimmelikhuijzen, Cornelis J P

    2002-12-13

    The Drosophila Genome Project website contains an annotated gene (CG14575) for a G protein-coupled receptor. We cloned this receptor and found that the cloned cDNA did not correspond to the annotated gene; it partly contained different exons and additional exons located at the 5(')-end of the annotated gene. We expressed the coding part of the cloned cDNA in Chinese hamster ovary cells and found that the receptor was activated by two neuropeptides, capa-1 and -2, encoded by the Drosophila capability gene. Database searches led to the identification of a similar receptor in the genome from the malaria mosquito Anopheles gambiae (58% amino acid residue identities; 76% conserved residues; and 5 introns at identical positions within the two insect genes). Because capa-1 and -2 and related insect neuropeptides stimulate fluid secretion in insect Malpighian (renal) tubules, the identification of this first insect capa receptor will advance our knowledge on insect renal function.

  6. A study of perianesthesia nursing practice: the foundation for newly revised CPAN and CAPA certification examinations.

    Science.gov (United States)

    Niebuhr, B S; Muenzen, P

    2001-06-01

    The CPAN and CAPA nursing certification programs, sponsored by ABPANC, are designed to promote and enhance the quality of care delivered to patients who have received anesthesia. This article describes ABPANC's most recent Role Delineation Study (RDS), also called the Study of Practice. The work of a think tank that convened to reconceptualize the organizing framework for the certification examination programs is described, including the results of an environmental analysis. A variety of methods were used to conduct the study. As a result of study findings, the CPAN and CAPA programs have been redesigned to focus on the physiological, behavioral and cognitive, safety, and advocacy needs of perianesthesia patients. Those needs and the knowledge base that is required of perianesthesia nurses to meet those needs are defined. The first CPAN and CAPA examinations using the new framework will be given November 3, 2001.

  7. Contributions to the Genesis and Progress of ICF

    Energy Technology Data Exchange (ETDEWEB)

    Nuckolls, J H

    2006-02-15

    Inertial confinement fusion (ICF) has progressed from the detonation of large-scale fusion explosions initiated by atomic bombs in the early 1950s to final preparations for initiating small-scale fusion explosions with giant lasers. The next major step after ignition will be development of high performance targets that can be initiated with much smaller, lower cost lasers. In the 21st century and beyond, ICF's grand challenge is to develop practical power plants that generate low cost, clean, inexhaustible fusion energy. In this chapter, I first describe the origin in 1960-61 of ICF target concepts, early speculations on laser driven 'Thermonuclear Engines' for power production and rocket propulsion, and encouraging large-scale nuclear explosive experiments conducted in 1962. Next, I recall the 40-year, multi-billion dollar ignition campaign - to develop a matched combination of sufficiently high-performance implosion lasers and sufficiently stable targets capable of igniting small fusion explosions. I conclude with brief comments on the NIF ignition campaign and very high-performance targets, and speculations on ICF's potential in a centuries-long Darwinian competition of future energy systems. My perspectives in this chapter are those of a nuclear explosive designer, optimistic proponent of ICF energy, and Livermore Laboratory leader. The perspectives of Livermore's post 1970 laser experts and builders, and laser fusion experimentalists are provided in a chapter written by John Holzrichter, a leading scientist and leader in Livermore's second generation laser fusion program. In a third chapter, Ray Kidder, a theoretical physicist and early laser fusion pioneer, provides his perspectives including the history of the first generation laser fusion program he led from 1962-1972.

  8. The capture proteasome assay (CAPA) to evaluate subtype-specific proteasome inhibitors.

    Science.gov (United States)

    Vigneron, Nathalie; Abi Habib, Joanna; Van den Eynde, Benoît J

    2015-09-01

    We recently developed a new assay to measure proteasome activity in vitro (CAPA for capture proteasome assay) [1], based on proteasome capture on an antibody-coated plate. When used with lysates originating from cells expressing either standard proteasome, immunoproteasome or intermediate proteasomes β5i or β1i-β5i, this assay allows the individual monitoring of the chymotrypsin-like, trypsin-like and caspase-like activities of the corresponding proteasome subtypes. The efficiency and specificity of four proteasome inhibitors were studied using the CAPA assay, demonstrating the potential of this assay for the development of subtype-specific proteasome inhibitors.

  9. Identification of the first neuropeptides from the CNS of Hemiptera: CAPA peptides of the southern green stinkbug Nezara viridula (L.).

    Science.gov (United States)

    Predel, Reinhard; Russell, William K; Neupert, Susanne; Russell, David H; Esquivel, Jesus F; Nachman, Ronald J

    2006-11-01

    A direct mass spectrometric investigation of nerve homologs of the abdominal perisympathetic organs was employed to reveal the first and complete sequences of CAPA peptides from a hemipteran species, the southern green stinkbug Nezara viridula. Side-chain fragmentations allowed the assignment of internal Leu/Ile; on-plate acetylation was used to distinguish between the mass-related Lys and Gln. The following sequences were obtained: DQLFPFPRV-NH(2) (CAPA-PVK-1), EQLIPFPRV-NH(2) (CAPA-PVK-2), and NGSAGNGGLWFGPRL/I-NH(2) (CAPA-PK). CAPA-PVKs are associated with the regulation of diuresis in insects, and identification of those native to a hemipteran will provide the experimental basis to better understand regulation of water balance in this family of insects.

  10. Serine phosphorylation of CAPA pyrokinin in cockroaches-a taxon-specific posttranslational modification.

    Science.gov (United States)

    Sturm, Sebastian; Predel, Reinhard

    2014-07-01

    In insects, posttranslational modifications of neuropeptides are largely restricted to C- and N-terminal amino acids. The most common modifications, N-terminal pyroglutamate formation and C-terminal α-amidation, may prevent a fast degradation of these messenger molecules. This is particularly important for peptide hormones. Other common posttranslational modifications of proteins such as glycosylation and phosphorylation seem to be very rare in insect neuropeptides. To check this assumption, we used a computer algorithm to search an extensive data set of MALDI-TOF mass spectra from cockroach tissues for ion signal patterns indicating peptide phosphorylation. The results verify that phosphorylation is indeed very rare. However, a candidate was found and experimentally verified as phosphorylated CAPA pyrokinin (GGGGpSGETSGMWFGPRL-NH2) in the cockroach Lamproblatta albipalpus (Blattidae, Lamproblattinae). Tandem mass spectrometry revealed the phosphorylation site as Ser(5). Phosphorylated CAPA pyrokinin was then also detected in most other cockroach lineages (e.g. Blaberidae, Polyphagidae) but not in closely related blattid species such as Periplaneta americana. This is remarkable since the sequence of CAPA pyrokinin is identical in Lamproblatta and Periplaneta. A consensus sequence of CAPA pyrokinins of cockroaches revealed a conserved motif that suggests phosphorylation by a Four-jointed/FAM20C related kinase.

  11. Un congreso de fisica estudia la composicion de las capas de la tierra

    CERN Document Server

    2003-01-01

    "El Congreso de Internacional de Neutrinos, que ayer comenzo en el Jardin Botanico de Valencia, aborda, entre otros aspectos, la composicion y el perfil tomografico de las distintas capas de estratos del interior de la Tierra, segun informo a Efe el profesor Jose Furtado Valle" (1/2 page).

  12. Structure and floristic similarities of upper montane forests in Serra Fina mountain range, southeastern Brazil

    Directory of Open Access Journals (Sweden)

    Leonardo Dias Meireles

    2015-03-01

    Full Text Available The upper montane forests in the southern and southeastern regions of Brazil have an unusual and discontinuous geographic distribution at the top of the Atlantic coastal mountain ranges. To describe the floristic composition and structure of the Atlantic Forest near its upper altitudinal limit in southeastern Brazil, 30 plots with 10 × 10 m were installed in three forest sites between 2,200 and 2,300 m.a.s.l. at Serra Fina. The floristic composition and phytosociological structure of this forest were compared with other montane and upper montane forests. In total, 704 individuals were included, belonging to 24 species, 15 families, and 19 genera. Myrsinaceae, Myrtaceae, Symplocaceae, and Cunoniaceae were the most important families, and Myrsine gardneriana, Myrceugenia alpigena, Weinmannia humilis, and Symplocos corymboclados were the most important species. The three forest sites revealed differences in the abundance of species, density, canopy height, and number of stems per individual. The upper montane forests showed structural similarities, such as lower richness, diversity, and effective number of species, and they tended to have higher total densities and total dominance per hectare to montane forests. The most important species in these upper montane forests belong to Austral-Antartic genera or neotropical and pantropical genera that are typical of montane areas. The high number of species shared by these forests suggests past connections between the vegetation in southern Brazilian high-altitude areas.

  13. Espectrometría de masas de iones secundarios: aportaciones a la técnica y caracterización de capas finas de a-C:H y de a-Si:H

    OpenAIRE

    López Fernández, Francisco

    1993-01-01

    Entre las técnicas microanalíticas, el SIMS ha experimentado un gran éxito en las dos últimas décadas. Su habilidad para proporcionar datos de composición elemental y estructura, su capacidad para detectar pequeñas concentraciones de elementos y su distribución en profundidad, etc.; ha hecho que el SIMS sea un instrumento muy útil en numerosos campos de la ciencia y la tecnología. Se ha de mencionar también que la limitación más importante que padece la técnica es su falta de carácter cuantit...

  14. Comparative study. Thin-film technology (si-a) compared to crystalline silicon in real operating conditions; Estudio comparativo. Tecnologia de capa fina (Si-a) frente a silicio cristalino en condiciones reales de funcionamiento

    Energy Technology Data Exchange (ETDEWEB)

    Izard Gomez-Rodulfo, J.; Avellaner, J.; Sanchez, E.; Torreblanca, J.

    2010-07-01

    We present a comparative study of thin film solar modules (amorphous silicon) compared to crystalline silicon modules. This study was conducted in real operating conditions using a test bench able to obtain the characteristic curve of several modules in sequence. defined the parameter efficiency index to characterize the extent to which actual performance is close to ideal. Finally we have calculated the energy that would produce each module in the day and efficiency in relation to the energy which ideally should produce. (Author)

  15. Analysis Of Wetted-Foam ICF Capsule Perormance

    Science.gov (United States)

    Peterson, R.; Olson, R.; Zylstra, A.; Haines, B.; Yi, A.; Bradley, P.; Yin, L.; Leeper, R.; Kline, J.

    2016-10-01

    The performance of wetted-foam ICF capsules is investigated with the RAGE Eulerian radiation-hydrodynamics computer code. We are developing an experimental platform on NIF that employs a wetted foam liquid DT fuel layer ICF capsules. By varying the capsule temperature, the vapor density in the capsule can be prescribed, and the hot spot convergence ratio (CR) of the capsule implosion can be controlled. This allows us to investigate the fidelity of RAGE in modeling of capsule implosions as the value of CR is varied. In the NIF experiments, CR can be varied from 12 to 25. This presentation will cover simulations with RAGE of three NIF shots performed in 2016; a DD and a DT liquid fuel shot with CR =14 and a DT shot with CR =16. It will also discuss analysis of future experiments. This work was performed under auspices of the U. S. DOE by LANL.

  16. FUNCTIONAL PROFILE OF ACTIVE OLDER ADULTS WITH LOW BACK PAIN, ACCORDING TO THE ICF

    Directory of Open Access Journals (Sweden)

    Andersom Ricardo Fréz

    Full Text Available ABSTRACT Introduction: The International Classification of Functioning, Disability and Health (ICF considers multiples aspects of functionality. It is believed that this tool can help to classify the functionality of older adults with low back pain (LBP . Objectives: To describe the functionality of active older adults with LBP according to the ICF. Methods: A transversal study was conducted using the brief ICF core set for low back pain, to establish functional profiles of 40 older adults. The ICF categories were considered valid when ≥20% of participants showed some disability. Results: Thirty-two of the 35 categories of the brief ICF core set could be considered representative of the sample. Conclusion: The brief ICF core set for LBP results demonstrated that this classification system is representative for describing the functional profile of the sample.

  17. Shoulder pain within the ICF framework; patient experiences of functioning and assessment methods

    OpenAIRE

    Røe, Yngve

    2014-01-01

    Introduction: Shoulder pain is a common, persistent and disabling disease. The restoration of abnormal movement-patterns is often an important goal in the treatment of patients with shoulder pain. The International Classification of Functioning, Disability and Health (ICF) is a conceptual framework and classification that has been developed by the World Health Organisation. The ICF is a common, multi-disciplinary language that allows identification of condition-specific codes (ICF categories)...

  18. Mediating effects of the ICF domain of function and the gross motor function measure on the ICF domains of activity, and participation in children with cerebral palsy.

    Science.gov (United States)

    Lee, Byoung-Hee; Kim, Yu-Mi; Jeong, Goo-Churl

    2015-10-01

    [Purpose] This study aimed to evaluate the mediating effect of gross motor function, measured using the Gross Motor Function Measure (GMFM) and of general function, measured using the International Classification of Functioning, Disability and Health-Child and Youth Check List (ICF-CY), on the ICF domains of activity and participation in children with cerebral palsy (CP). [Subjects] Ninety-five children with CP, from Seoul, Korea, participated in the study. [Methods] The GMFM was administered in its entirety to patients without orthoses or mobility aids. The ICF-CY was used to evaluate the degree of disability and health of subjects. [Results] GMFM score and ICF-CY function were negatively correlated to ICF-CY activity and participation. ICF-CY partially mediated the effects of the GMFM on activity and participation. [Conclusion] When establishing a treatment plan for a child with CP, limitations in activity and participation, as described by the ICF-CY, should be considered in addition to the child's physical abilities and development. In addition, the treatment plan should focus on increasing the child's activity and participation level, as well as his/her physical level.

  19. Purification and biophysical characterization of the CapA membrane protein FTT0807 from Francisella tularensis.

    Science.gov (United States)

    Martin-Garcia, Jose M; Hansen, Debra T; Zook, James; Loskutov, Andrey V; Robida, Mark D; Craciunescu, Felicia M; Sykes, Kathryn F; Wachter, Rebekka M; Fromme, Petra; Allen, James P

    2014-04-01

    The capA gene (FTT0807) from Francisella tularensis subsp. tularensis SCHU S4 encodes a 44.4 kDa integral membrane protein composed of 403 amino acid residues that is part of an apparent operon that encodes at least two other membrane proteins, CapB, and CapC, which together play a critical role in the virulence and pathogenesis of this bacterium. The capA gene was overexpressed in Escherichia coli as a C-terminal His6-tagged fusion with a folding reporter green fluorescent protein (frGFP). Purification procedures using several detergents were developed for the fluorescing and membrane-bound product, yielding approximately 30 mg of pure protein per liter of bacterial culture. Dynamic light scattering indicated that CapA-frGFP was highly monodisperse, with a size that was dependent upon both the concentration and choice of detergent. Circular dichroism showed that CapA-frGFP was stable over the range of 3-9 for the pH, with approximately half of the protein having well-defined α-helical and β-sheet secondary structure. The addition of either sodium chloride or calcium chloride at concentrations producing ionic strengths above 0.1 M resulted in a small increase of the α-helical content and a corresponding decrease in the random-coil content. Secondary-structure predictions on the basis of the analysis of the sequence indicate that the CapA membrane protein has two transmembrane helices with a substantial hydrophilic domain. The hydrophilic domain is predicted to contain a long disordered region of 50-60 residues, suggesting that the increase of α-helical content at high ionic strength could arise because of electrostatic interactions involving the disordered region. CapA is shown to be an inner-membrane protein and is predicted to play a key cellular role in the assembly of polysaccharides.

  20. X-ray ablation measurements and modeling for ICF applications

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Andrew Thomas [Univ. of California, Berkeley, CA (United States)

    1996-09-01

    X-ray ablation of material from the first wall and other components of an ICF (Inertial Confinement Fusion) chamber is a major threat to the laser final optics. Material condensing on these optics after a shot may cause damage with subsequent laser shots. To ensure the successful operation of the ICF facility, removal rates must be predicted accurately. The goal for this dissertation is to develop an experimentally validated x-ray response model, with particular application to the National Ignition Facility (NIF). Accurate knowledge of the x-ray and debris emissions from ICF targets is a critical first step in the process of predicting the performance of the target chamber system. A number of 1-D numerical simulations of NIF targets have been run to characterize target output in terms of energy, angular distribution, spectrum, and pulse shape. Scaling of output characteristics with variations of both target yield and hohlraum wall thickness are also described. Experiments have been conducted at the Nova laser on the effects of relevant x-ray fluences on various materials. The response was diagnosed using post-shot examinations of the surfaces with scanning electron microscope and atomic force microscope instruments. Judgments were made about the dominant removal mechanisms for each material. Measurements of removal depths were made to provide data for the modeling. The finite difference ablation code developed here (ABLATOR) combines the thermomechanical response of materials to x-rays with models of various removal mechanisms. The former aspect refers to energy deposition in such small characteristic depths (~ micron) that thermal conduction and hydrodynamic motion are significant effects on the nanosecond time scale. The material removal models use the resulting time histories of temperature and pressure-profiles, along with ancillary local conditions, to predict rates of surface vaporization and the onset of conditions that would lead to spallation.

  1. X-ray ablation measurements and modeling for ICF applications

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, A.T.

    1996-09-01

    X-ray ablation of material from the first wall and other components of an ICF (Inertial Confinement Fusion) chamber is a major threat to the laser final optics. Material condensing on these optics after a shot may cause damage with subsequent laser shots. To ensure the successful operation of the ICF facility, removal rates must be predicted accurately. The goal for this dissertation is to develop an experimentally validated x-ray response model, with particular application to the National Ignition Facility (NIF). Accurate knowledge of the x-ray and debris emissions from ICF targets is a critical first step in the process of predicting the performance of the target chamber system. A number of 1-D numerical simulations of NIF targets have been run to characterize target output in terms of energy, angular distribution, spectrum, and pulse shape. Scaling of output characteristics with variations of both target yield and hohlraum wall thickness are also described. Experiments have been conducted at the Nova laser on the effects of relevant x-ray fluences on various materials. The response was diagnosed using post-shot examinations of the surfaces with scanning electron microscope and atomic force microscope instruments. Judgments were made about the dominant removal mechanisms for each material. Measurements of removal depths were made to provide data for the modeling. The finite difference ablation code developed here (ABLATOR) combines the thermomechanical response of materials to x-rays with models of various removal mechanisms. The former aspect refers to energy deposition in such small characteristic depths ({approx} micron) that thermal conduction and hydrodynamic motion are significant effects on the nanosecond time scale. The material removal models use the resulting time histories of temperature and pressure-profiles, along with ancillary local conditions, to predict rates of surface vaporization and the onset of conditions that would lead to spallation.

  2. ICF quarterly report, October-December 1998, volume 8, number 4

    Energy Technology Data Exchange (ETDEWEB)

    Kaufmann, B

    1998-09-30

    The ICF Quarterly Report is pub-lished four times each fiscal year by the Inertial Confinement Fusion/National Ignition Facility and High-Energy-Density Experimental Science (ICF/NIF/ HEDES) Program at the Lawrence Livermore National Laboratory (LLNL). The journal summarizes selected current research achievements of the LLNLICF/NIF/HEDES Program.

  3. Sequence and expression of the CAPA/CAP2b gene in the tobacco hawkmoth, Manduca sexta.

    Science.gov (United States)

    Loi, Poh Kheng; Tublitz, Nathan J

    2004-10-01

    The gene coding for cardioacceleratory peptide 2b (CAP2b; pELYAFPRV) has been isolated and sequenced from the moth Manduca sexta (GenBank accession #AY649544). Because of its significant homology to the CAPA gene in Drosophila melanogaster, this gene is called the Manduca CAPA gene. The Manduca CAPA gene is 958 nucleotides long with 29 untranslated nucleotides from the beginning of the sequence to the putative start initiation site. The CAPA gene has a single open reading frame, 441 nucleotides long, that codes for a predicted precursor protein of 147 amino acids. The predicted prepropeptide encodes a single copy of each of three deduced propeptides, a CAP2b propeptide, with a Q substituted for an E at the N-terminus (QLYAFPRVa), and two novel CAP2b-related propeptides (DGVLNLYPFPRVa and TEGPGMWFGPRLa). To reduce confusion and to adopt a more standardized nomenclature, we rename pELYAFPRVa as Mas-CAPA-1 and assign the names of Mas-CAPA-2 to DGVLNLYPFPRVa and Mas-PK-1 (Pyrokinin-1) to TEGPGMWFGPRLa. The spatial and temporal expression pattern of the CAPA gene in the Manduca central nervous system (CNS) was determined in all major post-embryonic stages using in situ hybridization techniques. The CAPA gene is expressed in a total of 27 pairs of neurons in the post-embryonic Manduca CNS. A total of 16 pairs of cells is observed in the brain, two pairs in the sub-esophageal ganglion (SEG), one pair in the third thoracic ganglion (T3), one pair in each unfused abdominal ganglion (A1-A6) and two pairs in the fused terminal ganglion. The mRNA from the CAPA gene is present in nearly every ganglion in each post-embryonic stage. The number of cells expressing the CAPA gene varies during post-embryonic life, starting at 54 cells in first-instar larvae and declining to a minimum of 14 cells midway through adult development.

  4. Barriers, activities and participation: Incorporating ICF into service planning datasets.

    LENUS (Irish Health Repository)

    O'Donovan, MA

    2009-05-21

    Purpose. Guided by the World Health Organization\\'s International Classification of Functioning, Disability and Health (ICF), a measure of activity and participation (MAP) was developed and incorporated into the National Physical and Sensory Disability Database in Ireland. The aims of this article are to investigate and explore the relationship between the barriers, participation restriction and functioning levels experienced by people with disabilities. Method. Seven thousand five hundred and sixty-two personal interviews with people meeting specific eligibility criteria for registering onto the database were conducted across four health service executive regions in Ireland. Results. Overall, differences in barriers, participation restriction and activity limitations experienced by people with different types of disabilities were found to be significant. Furthermore, low functioning and experience of barriers were indicators of participation restriction. Conclusions. This article has shown that elements of the ICF have been successfully operationalised in a service planning tool through the development of the MAP. This provides a more holistic view of disability and will enable the impact of service interventions to be measured over time.

  5. ICF quarterly report January - March 1997 volume 7, number 3

    Energy Technology Data Exchange (ETDEWEB)

    Murray, J

    1998-04-09

    The National Ignition Facility Project The mission of the National Ignition Facility (NIF) is to produce ignition and modest energy gain in inertial confinement fusion (ICF) targets. Achieving these goals will maintain U.S. world leadership in ICF and will directly benefit the U.S. Department of Energy (DOE) missions in national security, science and technology, energy resources, and industrial competitiveness. Development and operation of the NIF are consistent with DOE goals for environmental quality, openness to the community, and nuclear nonproliferation and arms control. Although the primary mission of inertial fusion is for defense applications, inertial fusion research will provide critical information for the development of inertial fusion energy. The NIF, under construction at Lawrence Livermore National Laboratory (LLNL), is a cornerstone of the DOE's science-based Stockpile Stewardship Program for addressing high-energy-density physics issues in the absence of nuclear weapons testing. In pursuit of this mission, the DOE's Defense Programs has developed a state-of-the-art capability with the NIF to investigate high-energy-density physics in the laboratory with a microfusion capability for defense and energy applications. As a Strategic System Acquisition, the NIF Project has a separate and disciplined reporting chain to DOE as shown below.

  6. Kr X-ray spectroscopy to diagnose NIF ICF implosions

    Science.gov (United States)

    Dasgupta, A.; Ouart, N.; Giuliani, J. L.; Clark, R. W.; Schneider, M. B.; Scott, H. A.; Chen, H.; Ma, T.; Apruzese, J. P.

    2016-10-01

    X ray spectroscopy is used on the NIF to diagnose the plasma conditions in the ignition target in indirect drive ICF implosions. High-energy emission spectra from mid to high atomic number elements can provide estimates of electron temperature near stagnation of an ICF implosion. A platform is being developed at NIF where small traces of krypton are used as a dopant to the fuel gas for spectroscopic diagnostics using krypton line emissions. The fraction of krypton dopant was varied in the experiments and was selected so as not to perturb the implosion. Simulations of the krypton spectra using a 1 in 104 atomic fraction of krypton in direct-drive exploding pusher with a range of electron temperatures and densities show discrepancies when different atomic models are used. We use our non-LTE atomic model with a detailed fine-structure level atomic structure and collisional-radiative rates to investigate the krypton spectra at the same conditions. Synthetic spectra are generated with a detailed multi-frequency radiation transport scheme from the emission regions of interest to analyze the experimental data and compare and contrast with the existing simulations at LLNL. Work supported by DOE/NNSA and under the auspices of DOE by LLNL under Contract # DE-AC52-07NA27344.

  7. Wetted Foam Liquid DT Layer ICF Experiments at the NIF

    Science.gov (United States)

    Olson, R. E.; Leeper, R. J.; Peterson, R. R.; Yi, S. A.; Zylstra, A. B.; Kline, J. L.; Bradley, P. A.; Yin, L.; Wilson, D. C.; Haines, B. M.; Batha, S. H.

    2016-10-01

    A key physics issue in indirect-drive ICF relates to the understanding of the limitations on hot spot convergence ratio (CR), principally set by the hohlraum drive symmetry, the capsule mounting hardware (the ``tent''), and the capsule fill tube. An additional key physics issue relates to the complex process by which a hot spot must be dynamically formed from the inner ice surface in a DT ice-layer implosion. These physics issues have helped to motivate the development of a new liquid DT layer wetted foam platform at the NIF that provides an ability to form the hot spot from DT vapor and experimentally study and understand hot spot formation at a variety of CR's in the range of 12ICF ignition. This work was performed under the auspices of the U. S. DOE by LANL under contract DE-AC52-06NA25396.

  8. Initiation of extended arc discharge in ICF reactor dense atmospheres

    Energy Technology Data Exchange (ETDEWEB)

    Kislev, H.

    1986-01-01

    Reduced density plasma channels are essential for LIB transport from external diodes to an ICF pellet centered in the 2-4 MPa superheated steamfilled cavity of the Heavy Water ICF Reactor. Forming such channels by ohmic heating requires the initiation of straight arc discharges along each beamline. The goal of this thesis is to evaluate the threshold beamline preionization and applied electric field for arc initiation. The capability of several preionizers to produce a straight preionized trail is evaluated through a ten-group Boltzmann equation solver. Electron densities around 10/sup 17/ m/sup -3/ could be maintained in the trail by monojoule output external preionizers. Trail preionization through the co-application of UV and CO/sub 2/ lasers appears to be the most promising technique. UV laser preionization of NO(a/sup 4/..pi..) formed in the fireball shows also good prospective. The large divergence of soft x-ray sources reduces their attractivity. The E/N dependent electron transport properties are used to construct the first streamer model capable of evaluating the steady state streamer wave shape. The streamers-induced highly ionized filament transition into a multi-kA carrying plasma channel is simulated by a modified radiation-MHD one-dimensional code.

  9. Opacity spectra of silicon and carbon in ICF plasmas

    Science.gov (United States)

    Benredjem, D.; Calisti, A.; Ferri, S.; Gilleron, F.; Mondet, G.; Pain, J.-C.

    2017-03-01

    The knowledge of opacity is very important when one investigates the radiative properties of ICF and astrophysical plasmas. Germanium and silicon are good candidates as dopants in the ablator of some ICF schemes (LMJ in France, NIF at Livermore). In this work we calculate the opacity spectra of silicon and carbon mixtures. Two competitive methods were used. The first one is based on a detailed line calculation in which the atomic database is provided by the MCDF code. A lineshape code based on a fast algorithm was then adapted to the calculation of opacity profiles. All major line broadening mechanisms, including Zeeman splitting and Stark effect, are taken into account. This approach provides accurate opacity spectra but becomes rapidly prohibitive when the number of lines is large. To account for systems involving many ionic stages and thousands of lines, a second approach combines detailed line calculations and statistical calculations. This approach necessitates much smaller calculation times than the first one and is then more appropriate for extensive calculations. The monochromatic opacity and the Rosseland and Planck mean opacities are calculated for relevant densities and temperatures.

  10. Improved ICF implosion performance through precision engineering features

    Science.gov (United States)

    Weber, Christopher

    2016-10-01

    The thin membrane that holds the capsule in-place in the hohlraum is recognized as one of the most significant contributors to reduced performance in indirect drive inertial confinement fusion (ICF) experiments on the National Ignition Facility (NIF). This membrane, known as the ``tent'', seeds a perturbation that is amplified by Rayleigh-Taylor and can rupture the capsule. The ICF program is undertaking a major effort to develop a less damaging capsule support mechanism. Possible alternatives include micron-scale rods spanning the hohlraum width and supporting either the capsule or stiffening the fill-tube, a larger fill-tube to both fill and support the capsule, or a low-density foam layer that protects the capsule from the tent impact. In addition to the challenges presented by nano and microscale engineering, it is difficult to model and experimentally verify improvement from these changes. The 3D nature of the proposed replacements and the radiation shadows they cast on the capsule prohibit direct simulation. Therefore a combination of reduced models and experimental verification are used to set requirements and down-select the options. Ultimately the improved capsule support will be used to repeat a DT-layered implosion and demonstrate improved performance. Work performed under the auspices of the U.S. D.O.E. by Lawrence Livermore National Laboratory under Contract No. DE-AC52-07NA27344.

  11. Heterochromatic genes undergo epigenetic changes and escape silencing in immunodeficiency, centromeric instability, facial anomalies (ICF syndrome.

    Directory of Open Access Journals (Sweden)

    Marie-Elisabeth Brun

    Full Text Available Immunodeficiency, Centromeric Instability, Facial Anomalies (ICF syndrome is a rare autosomal recessive disorder that is characterized by a marked immunodeficiency, severe hypomethylation of the classical satellites 2 and 3 associated with disruption of constitutive heterochromatin, and facial anomalies. Sixty percent of ICF patients have mutations in the DNMT3B (DNA methyltransferase 3B gene, encoding a de novo DNA methyltransferase. In the present study, we have shown that, in ICF lymphoblasts and peripheral blood, juxtacentromeric heterochromatic genes undergo dramatic changes in DNA methylation, indicating that they are bona fide targets of the DNMT3B protein. DNA methylation in heterochromatic genes dropped from about 80% in normal cells to approximately 30% in ICF cells. Hypomethylation was observed in five ICF patients and was associated with activation of these silent genes. Although DNA hypomethylation occurred in all the analyzed heterochromatic genes and in all the ICF patients, gene expression was restricted to some genes, every patient having his own group of activated genes. Histone modifications were preserved in ICF patients. Heterochromatic genes were associated with histone modifications that are typical of inactive chromatin: they had low acetylation on H3 and H4 histones and were slightly enriched in H3K9Me(3, both in ICF and controls. This was also the case for those heterochromatic genes that escaped silencing. This finding suggests that gene activation was not generalized to all the cells, but rather was restricted to a clonal cell population that may contribute to the phenotypic variability observed in ICF syndrome. A slight increase in H3K27 monomethylation was observed both in heterochromatin and active euchromatin in ICF patients; however, no correlation between this modification and activation of heterochromatic genes was found.

  12. Comparative analysis of the Tyr-kinases CapB1 and CapB2 fused to their cognate modulators CapA1 and CapA2 from Staphylococcus aureus.

    Directory of Open Access Journals (Sweden)

    Jakub Gruszczyk

    Full Text Available A particular class of tyrosine-kinases sharing no structural similarity with eukaryotic tyrosine-kinases has been evidenced in a large array of bacterial species. These bacterial tyrosine-kinases are able to autophosphorylate on a C-terminal tyrosine-rich motif. Their autophosphorylation has been shown to play a crucial role in the biosynthesis or export of capsular polysaccharide. The analysis of the first crystal structure of the staphylococcal tyrosine kinase CapB2 associated with the activating domain of the transmembrane modulator CapA1 had brought conclusive explanation for both the autophosphorylation and activation processes. In order to explain why CapA1 activates CapB2 more efficiently than its cognate transmembrane modulator CapA2, we solved the crystal structure of CapA2B2 and compared it with the previously published structure of CapA1B2. This structural analysis did not provide the expected clues about the activation discrepancy observed between the two modulators. Staphylococcus aureus also encodes for a CapB2 homologue named CapB1 displaying more than 70% sequence similarity and being surprisingly nearly unable to autophosphorylate. We solved the crystal structure of CapA1B1 and carefully compare it with the structure of CapA1B2. The active sites of both proteins are highly conserved and the biochemical characterization of mutant proteins engineered to test the importance of small structural discrepancies identified between the two structures did not explain the inactivity of CapB1. We thus tested if CapB1 could phosphorylate other protein substrates or hydrolyze ATP. However, no activity could be detected in our in vitro assays. Taken together, these data question about the biological role of the homologous protein pairs CapA1/CapB1 and CapA2/CapB2 and we discuss about several possible interpretations.

  13. ICF Ignition, the Lawson Criterion, and Comparison with MFE Ignition

    Science.gov (United States)

    Betti, R.

    2009-11-01

    The Lawson criterion, which determines the onset of thermonuclear ignition, is usually expressed through the product pτ > 10 atm . s, where p is the plasma pressure in atm and τ is the energy confinement time in seconds. In magnetic fusion devices, both the pressure and confinement time are routinely measured and the performance of each discharge can be assessed by comparing the value of pτ with respect to the ignition value (10 atm . s). In inertial confinement fusion, both p and τ cannot be directly measured and the performance of surrogate and/or subignited ICF implosions cannot be assessed with respect to the ignition condition. This makes it difficult to compare the performance of ICF implosions with that of magnetic fusion energy (MFE) discharges. Here, we define the meaning of ignition in ICF implosions and compare it to MFE ignition. We then show that a multidimensional ignition condition for inertial confinement fusion can be cast in a form that depends on three measurable parameters of the compressed-fuel assembly: the hot-spot ion temperature T, the neutron yield normalized to the 1-D prediction (yield over clean or YOC) and the total areal density ρR, which includes the cold shell's contribution. A family of marginal-ignition curves are derived in the ρR--T plane.footnotetext C. D. Zhou and R. Betti, Phys. Plasmas 15, 102707 (2008). On this plane, hydrodynamic-equivalent curves show how a given implosion would perform with respect to the ignition condition when the laser-driver energy is varied. Such a criterion can be used to measure the ignition marginfootnotetext D. S. Clark, S. W. Haan, and J. D. Salmonson, Phys. Plasmas 15, 056305 (2008). of NIF targets and to predict the performance of OMEGA targets when scaled up to NIF energies. This work has been supported by the US Department of Energy under Cooperative Agreement Nos. DE-FC02-ER54789 and DE-FC52-08NA28302.

  14. Tribología de nuevas capas autolubricantes producidas mediante PVD

    Directory of Open Access Journals (Sweden)

    Oñate, J. I.

    2005-12-01

    Full Text Available MoS2 coatings, deposited by PVD show a low friction under vacuum conditions, but degrade easily under atmospheric conditions. This work describes the development of a new type of MoSx, coating, modified with WC. These coatings presented a very low and stable friction coefficient lower than 0.04 when tested under vacuum at 0.75 GPa in a ball on disc tribometer. Durability was higher than 1 million wear cycles, showing a wear rate of 1.3 10-16 m3/Nm. When tested under atmospheric conditions and up to 70 % RH, friction increased to 0.15 and durability reached a lower value of up to 3 x 105 cycles. Surface analyses in these coatings showed S/Mo ratios higher than 1.2 and with oxygen levels lower than 2 %, demonstrating the lubricant character of the coating.

    Las capas de MoS2 depositadas mediante PVD tienen baja fricción en vacío pero se degradan con facilidad al aire, especialmente en presencia de humedad. Este trabajo describe el desarrollo de nuevas capas de MoSx modificadas con WC. En ensayos de "bola sobre disco" a 0,75 GPa, las capas presentaron una fricción muy baja y estable (< 0,04 en vacío. Se obtuvo una durabilidad superior a 1 millón de ciclos, mostrando un desgaste de 1,3 x 10-16 m3/Nm, mejorado respecto a otras capas de MoSx. El coeficiente de fricción aumentó a 0,15 y la durabilidad disminuyó hasta 1 a 3 x 105 ciclos en aire hasta 70 % HR. El análisis superficial mostró ratios de S/Mo superiores a 1,2, con menos del 2 % de oxígeno, demostrando carácter lubricante.

  15. Revisión sobre la herencia del color de la capa en ganado bovino

    OpenAIRE

    Royo, L. J.; Fernández, Itziar; Álvarez, Isabel; Rodríguez, A.; Goyache, Félix

    2013-01-01

    Coat colour affects differentiation of populations into breeds. Additionally some authors proposed the use of the genes responsible of coat colour variation in diversity studies. In this work we review the knowledge on genes affecting coat colour (loci Extension or Mc r1 and Agouti or ASIP) AND SPOTTING PATTERNS (KIT and MGF) El interés por el color de la capa en ganado bovino reside en su importancia para la formación y diferenciación de las razas y en la posible utilización de los genes ...

  16. O controle espetacular nas capas da revista Veja : uma analise discursiva

    OpenAIRE

    Elissandro Martins Inacio

    2008-01-01

    Resumo: Este trabalho tem como objetivo refletir, a partir de uma perspectiva discursiva, sobre a constituição do acontecimento discursivo relativo à política. Para nosso estudo, desenvolvemos uma análise a partir da noção de acontecimento de Michel Foucault (2002). Visando descrever a constituição do discurso político como controle por meio da formação de saber espetacular, selecionamos algumas capas da revista Veja. Ao descrevermos práticas institucionais da Veja, possibilitamos ao leitor d...

  17. Mallas tensegríticas de doble capa y manipulaciones de Rot-Umbela

    Directory of Open Access Journals (Sweden)

    Gómez-Jáuregui, V.

    2012-09-01

    Full Text Available Double-layer tensegrity grids (DLTGs are tensegrity spatial systems containing two parallel networks of members in tension forming the top and bottom chords, whose nodes are linked by vertical and/or inclined web members under compression and tension. This paper presents, as an introduction, a brief perspective of the historical proposals for DLTGs over the last years, describing later a new approach for generating these kinds of structures, mainly in geometrical terms. After applying Otero’s proposal for designing conventional double-layer grids (DLGs, a new technique, known as Rot-Umbela Manipulation, is applied to their upper and/or lower layers for generating DLTGs. Rot-Umbela Manipulation consists of opening a vertex in the plane for obtaining a certain polygon, which is then rotated by a determined angle. This powerful operation opens an endless catalogue of DLTGs and a very interesting line of research in the field of Tensegrity.

    Las mallas tensegríticas de doble capa (MTDC son estructuras de Tensegridad que contiene dos mallas traccionadas paralelas, unidas por otra capa intermedia compuesta por elementos comprimidos y traccionados verticales y/o diagonales. Este trabajo presenta inicialmente un breve repaso sobre las propuestas de MTDC que se han realizado hasta el momento, exponiendo luego una nueva metodología, eminentemente geométrica, para la generación de este tipo de estructuras tensegríticas. Tras aplicar la propuesta de Otero para generar mallas de doble capa (MDC convencionales, se procede a realizar Manipulaciones de Rot-Umbela en las capas inferior y/o superior para convertir dicha estructura en una MTDC. Las Manipulaciones de Rot-Umbela consisten en la apertura de cada vértice en un cierto polígono, al cual se le aplica una rotación o giro particular. Se consigue así un potente sistema para “tensegritizar” MDC convencionales y abrir una línea de investigación muy interesante en el campo de la

  18. Brief Introduction to CAPA%亚太会计师联合会简介

    Institute of Scientific and Technical Information of China (English)

    钟国

    2005-01-01

    亚太会计师联合会(CAPA)是亚洲及太平洋地区会计行业组织的代表,截至2004年12月31日,共拥有来自23个国家的33个会计组织会员,是迄今为止世界上规模最大的区域性会计组织,覆盖全球约一半的区域。

  19. Mass spectrometric analysis of putative capa-gene products in Musca domestica and Neobellieria bullata.

    Science.gov (United States)

    Predel, Reinhard; Russell, William K; Tichy, Shane E; Russell, David H; Nachman, Ronald J

    2003-10-01

    Neuropeptides of the capa-gene are typical of the abdominal neurosecretory system of insects. In this study, we investigated these peptides in two widely distributed and large pest flies, namely Musca domestica and Neobellieria bullata. Using a combination of MALDI-TOF and ESI-QTOF mass spectrometry, periviscerokinins and a pyrokinin were analyzed from single perisympathetic organ preparations. The species-specific peptide sequences differ remarkably between the related dipteran species. These differences could make it possible to develop peptide-analogs with group- or species-specific efficacy.

  20. Thermodynamic and dynamical properties of dense ICF plasma

    Directory of Open Access Journals (Sweden)

    Gabdullin Maratbek T.

    2016-06-01

    Full Text Available In present work, thermodynamic expressions were obtained through potentials that took into consideration long-range many-particle screening effects as well as short-range quantum-mechanical effects and radial distribution functions (RDFs. Stopping power of the projectile ions in dense, non-isothermal plasma was considered. One of the important values that describe the stopping power of the ions in plasma is the Coulomb logarithm. We investigated the stopping power of ions in inertial confinement fusion (ICF plasma and other energetic characteristics of fuel. Calculations of ions energy losses in the plasma for different values of the temperature and plasma density were carried out. A comparison of the calculated data of ion stopping power and energy deposition with experimental and theoretical results of other authors was also performed.

  1. Numerical analysis of anisotropic diffusion effect on ICF hydrodynamic instabilities

    Directory of Open Access Journals (Sweden)

    Olazabal-Loumé M.

    2013-11-01

    Full Text Available The effect of anisotropic diffusion on hydrodynamic instabilities in the context of Inertial Confinement Fusion (ICF flows is numerically assessed. This anisotropy occurs in indirect-drive when laminated ablators are used to modify the lateral transport [1,2]. In direct-drive, non-local transport mechanisms and magnetic fields may modify the lateral conduction [3]. In this work, numerical simulations obtained with the code PERLE [4], dedicated to linear stability analysis, are compared with previous theoretical results [5]. In these approaches, the diffusion anisotropy can be controlled by a characteristic coefficient which enables a comprehensive study. This work provides new results on the ablative Rayleigh-Taylor (RT, ablative Richtmyer-Meshkov (RM and Darrieus-Landau (DL instabilities.

  2. Flux-limitation of the Nernst effect in magnetized ICF

    Science.gov (United States)

    Ridgers, Christopher; Barrois, Rion; Wengraf, Joshua; Bissell, John; Brodrick, Jonathan; Kingham, Robert; Read, Martin

    2016-10-01

    Magnetized ICF is a promising scheme which combines the advantages of magnetic and inertial confinement fusion. In the relevant high-energy density plasmas magnetic field evolution is often controlled by the Nernst effect where the magnetic field advects with the electron heat flow. It is well known that non-local thermal transport necessitates a flux-limiter on the heat flow. This suggests that a flux-limiter should also be applied to the Nernst effect. We have shown that this is the case using Vlasov-Fokker-Planck simulations and that the flux-limter is not the same as that required for the heat flow itself, for example when a NIF-relevant flux-limiter of 0.15 is required to limit the heat flow a Nernst flux limiter of 0.08 is required. We acknowledge support from EPSRC Grant No. EPM011372/1.

  3. Improved algorithm of ray tracing in ICF cryogenic targets

    Science.gov (United States)

    Zhang, Rui; Yang, Yongying; Ling, Tong; Jiang, Jiabin

    2016-10-01

    The high precision ray tracing inside inertial confinement fusion (ICF) cryogenic targets plays an important role in the reconstruction of the three-dimensional density distribution by algebraic reconstruction technique (ART) algorithm. The traditional Runge-Kutta methods, which is restricted by the precision of the grid division and the step size of ray tracing, cannot make an accurate calculation in the case of refractive index saltation. In this paper, we propose an improved algorithm of ray tracing based on the Runge-Kutta methods and Snell's law of refraction to achieve high tracing precision. On the boundary of refractive index, we apply Snell's law of refraction and contact point search algorithm to ensure accuracy of the simulation. Inside the cryogenic target, the combination of the Runge-Kutta methods and self-adaptive step algorithm are employed for computation. The original refractive index data, which is used to mesh the target, can be obtained by experimental measurement or priori refractive index distribution function. A finite differential method is performed to calculate the refractive index gradient of mesh nodes, and the distance weighted average interpolation methods is utilized to obtain refractive index and gradient of each point in space. In the simulation, we take ideal ICF target, Luneberg lens and Graded index rod as simulation model to calculate the spot diagram and wavefront map. Compared the simulation results to Zemax, it manifests that the improved algorithm of ray tracing based on the fourth-order Runge-Kutta methods and Snell's law of refraction exhibits high accuracy. The relative error of the spot diagram is 0.2%, and the peak-to-valley (PV) error and the root-mean-square (RMS) error of the wavefront map is less than λ/35 and λ/100, correspondingly.

  4. CONTRIBUCION AL ESTUDIO DE LA DURACION DE LA GESTACION Y SU RELACION CON EL RENDIMIENTO DEL PRODUCTO EQUINO FINA SANGRE DE CARRERA.

    OpenAIRE

    SANCHEZ RIQUELME, ALFONSO EDUARDO

    1998-01-01

    El creciente valor del caballo Fina Sangre de Carrera (FSC), dado por las altas sumas de dinero que se transan en el medio hípico, ha favorecido un importante desarrollo del conocimiento en el área de la medicina y reproducción equina. En la explotación p 94p.

  5. Cooking impact in color, pigments and volatile composition of grapevine leaves (Vitis vinifera L. var. Malvasia Fina and Touriga Franca).

    Science.gov (United States)

    Lima, Adriano; Pereira, José Alberto; Baraldi, Ilton; Malheiro, Ricardo

    2017-04-15

    Grapevine leaves (Vitis vinifera L. var. Malvasia Fina and Touriga Franca) under culinary treatment (blanching and boiling at 60, 75 and 90min) were studied for their color, pigments and volatile fraction changes. Blanching and boiling caused a decrease in luminosity and a loss of green coloration in both varieties, while a yellow-brownish color arose. Significant correlations were established between the loss of green color (monochromatic variable a(∗)) and the total chlorophylls content. The main volatiles in fresh leaves [(Z)-3-hexenal, (Z)-3-hexen-1-ol, and (Z)-3-hexenyl acetate] were drastically reduced by blanching and suppressed by boiling. Other compounds like pentanal and 6-methyl-5-hepten-2 one arose from blanching and boiling. A boiling time of 60min is adequate for the culinary process of grapevine leaves, since the product is considered edible and the pigments and volatile changes are not as drastic as observed at 75 and 90min of boiling.

  6. Control de Sustancias Agotadoras de la Capa de Ozono (SAO en vehículos importados

    Directory of Open Access Journals (Sweden)

    Miguel Antonio Cano-Pérez

    2011-01-01

    Full Text Available Se aborda el estudio sobre importaciones de vehículos, realizadas en la provincia de Holguín por las entidades MOA DIESEL S.A. y UNEVOL S.A, en el año 2009, con sistemas de aire acondicionado incorporados, sin la comprobación por la Aduana, ni por los especialistas del Centro de Inspección Ambiental del Ministerio de Ciencia, Tecnología y Medio Ambiente (CITMA acreditados al efecto, del tipo de gas refrigerante de los sistemas de climatización. Señala las partidas arancelarias de los vehículos que presentan los sistemas con gases refrigerantes y sustancias agotadoras de la capa de ozono. Argumenta que al no estar oficialmente establecido el control de ellos en los aires acondicionados de los vehículos, deja una brecha abierta por la cual pueden entrar alpaís sustancias agotadoras de la capa de ozono, sin el debido control, ni la correspondiente certificación. Se presentó la propuesta de la vía y forma para el control tanto por la Aduana, como por el CITMA.

  7. COMPORTAMIENTO ESTACIONAL DE LA CAPA DE MEZCLA MARINA EN LA REGIÓN NORTE DEL GOLFO DE CALIFORNIA

    OpenAIRE

    Emilio Palacios Hernández; Laura Carrillo B.

    2016-01-01

    Se realiza l a descripción de la profundidad de la capa de mezcla marina superficial (PCM) en la Región Norte del Golfo de California (RNGC), utilizando datos hidrográficos obtenidos en 17 cruceros oceanográficos desde 1971 hasta 1996. La profundidad de la capa se estima directament e de los perfiles de densidad . El promedio de distribución espacial muestra un máximo bien definido en la salida del canal de Ballenas y un mínimo en las costas de Sonora y de Baja ...

  8. Clinical spectrum of immunodeficiency, centromeric instability and facial dysmorphism (ICF syndrome).

    NARCIS (Netherlands)

    Hagleitner, M.M.; Lankester, A.; Maraschio, P.; Hulten, M.; Fryns, J.P.; Schuetz, C.; Gimelli, G.; Davies, E.G.; Gennery, A.; Belohradsky, B.H.; Groot, R. de; Gerritsen, E.J.; Mattina, T.; Howard, P.J.; Fasth, A.; Reisli, I.; Furthner, D.; Slatter, M.A.; Cant, A.J.; Cazzola, G.; Dijken, P.J. van; Deuren, M. van; Greef, J.C. de; Maarel, S.M. van der; Weemaes, C.M.R.

    2008-01-01

    BACKGROUND: Immunodeficiency, centromeric instability and facial dysmorphism (ICF syndrome) is a rare autosomal recessive disease characterised by facial dysmorphism, immunoglobulin deficiency and branching of chromosomes 1, 9 and 16 after PHA stimulation of lymphocytes. Hypomethylation of DNA of a

  9. Development of consensus International Classification of Functioning, Disability and Health (ICF) core sets for lymphedema

    NARCIS (Netherlands)

    Viehoff, P.B.; Heerkens, Y.F.; Ravensberg, C.D. van; Hidding, J.; Damstra, R.J.; Napel, H. ten; Neumann, H.A.

    2015-01-01

    To understand the challenges of patients with lymphedema it is important to describe functioning and to measure the effectiveness of treatment in changing functioning. The International Classification of Functioning, Disability and Health (ICF) offers an international framework to classify functioni

  10. Coding of meaningful concepts in lymphedema-specific questionnaires with the ICF

    NARCIS (Netherlands)

    Viehoff, P.B.; Hidding, J.T.; Heerkens, Y.F.; Ravensberg, C.D. van; Neumann, H.A.

    2013-01-01

    Abstract Purpose: To identify and quantify the meaningful concepts within questionnaires focusing on lymphedema using the International Classification of Functioning, Disability and Health (ICF). Methods: Electronic searches of Medline, EMBASE, CINAHL, CENtral and Pedro (2005-2010) were conducted. T

  11. Looking at the ICF and human communication through the lens of classification theory.

    Science.gov (United States)

    Walsh, Regina

    2011-08-01

    This paper explores the insights that classification theory can provide about the application of the International Classification of Functioning, Disability and Health (ICF) to communication. It first considers the relationship between conceptual models and classification systems, highlighting that classification systems in speech-language pathology (SLP) have not historically been based on conceptual models of human communication. It then overviews the key concepts and criteria of classification theory. Applying classification theory to the ICF and communication raises a number of issues, some previously highlighted through clinical application. Six focus questions from classification theory are used to explore these issues, and to propose the creation of an ICF-related conceptual model of communicating for the field of communication disability, which would address some of the issues raised. Developing a conceptual model of communication for SLP purposes closely articulated with the ICF would foster productive intra-professional discourse, while at the same time allow the profession to continue to use the ICF for purposes in inter-disciplinary discourse. The paper concludes by suggesting the insights of classification theory can assist professionals to apply the ICF to communication with the necessary rigour, and to work further in developing a conceptual model of human communication.

  12. Experiences using the open-source learning content management and assessment system LON-CAPA in introductory physics courses

    Science.gov (United States)

    Kortemeyer, Gerd; Kashy, Edwin; Benenson, Walter; Bauer, Wolfgang

    2008-04-01

    We discuss the development and functionality of the LON-CAPA system with a particular focus on its homework and examination functionality. We also describe its more general approach to course management and its infrastructure for course content sharing and reuse. We then focus on measures of student learning and the effectiveness of different content types.

  13. Rotational spectra and properties of complexes B···ICF3 (B = Kr or CO) and a comparison of the efficacy of ICl and ICF3 as iodine donors in halogen bond formation.

    Science.gov (United States)

    Stephens, Susanna L; Walker, Nicholas R; Legon, Anthony C

    2011-12-14

    The ground-state rotational spectra of two weakly bound complexes B···ICF(3) (B = Kr or CO) formed by trifluoroiodomethane have been observed in pulsed jets by using two types of Fourier-transform microwave spectroscopy (chirped-pulse and Fabry-Perot cavity). Both complexes exhibit symmetric-top type spectra, thus indicating that the Kr atom in Kr···ICF(3) and both the C and O atoms in OC···ICF(3) lie along the C(3) axis of ICF(3). The rotational constant B(0), the centrifugal distortion constants D(J) and D(JK), and the iodine nuclear quadrupole coupling constant χ(aa)(I) were determined for each of the isotopologues (84)Kr···ICF(3), (86)Kr···ICF(3), (16)O(12)C···ICF(3), (16)O(13)C···ICF(3), and (18)O(12)C···ICF(3). Interpretation of the spectroscopic constants reveals that the carbon atom of CO is adjacent to I and participates in the weak bond in OC···ICF(3). Simple models based on unperturbed component geometries lead to the distances r(Kr···I) = 3.830(1) Å and r(C···I) = 3.428(1) Å in Kr···ICF(3) and OC···ICF(3), respectively, and to the quadratic force constants for stretching of the weak bond k(σ) = 2.80 N m(-1) and 3.96 N m(-1), respectively. The distances r(Z···I) (Z is the acceptor atom in B), the k(σ) values, and the angular geometries of the pair of complexes B···ICF(3) and B···ICl for a given B are compared when B = Kr, CO, H(2)O, H(2)S, or NH(3). The comparison reveals that the iodine bond in B···ICF(3) is systematically longer and weaker than that of B···ICl, while the angular geometry of the B···I moiety is isomorphic in B···ICF(3) and B···ICl for a given B. It is concluded that -CF(3) is less effective than -Cl as an electron-withdrawing group when attached to an I atom and that the angular geometries of the B···ICF(3) can be predicted by means of a simple rule that holds for many hydrogen- and halogen-bonded complexes.

  14. Review of the three candidate hohlraums in ICF

    CERN Document Server

    Li, Xin; Dai, Zhensheng; Zheng, Wudi; Zhao, Yiqing; Zhang, Huasen; Gu, Jianfa; Kang, Dongguo; Ge, Fengjun; Gu, Peijun; Zou, Shiyang

    2016-01-01

    In this paper, we give a review of three hohlraum geometries, including cylindrical, octahedral and six-cylinder-port hohlraums, in inertial confinement fusion (ICF) mainly from theoretical side. Every hohlraum has its own strengths and weaknesses. Although there is a problem of drive asymmetry in the cylindrical hohlraums due to some non-ideal factors, the success of ignition is still possible if more laser energy is available beyond the US National Ignition Facility (NIF) in the future. Octahedral hohlraums can provide the high symmetry flux on capsule. However, octahedral hohlraums suffer from several problems due to the complicated three-dimensional plasma conditions inside. And up to now, there is no one target design with the octahedral hohlraums in which each problem can be solved at the same time. Six-cylinder-port hohlraums combine the merits in theory of both cylindrical and octahedral hohlraums to a certain extent. We introduce a target design with good performance by using the six-cylinder-port ho...

  15. Fuel Cavity Asymmetry at the Onset of Deceleration in ICF

    Science.gov (United States)

    Shah, Rahul C.; Wysocki, F. J.; Glebov, V.; Hakel, P.; Joshi, T.; Kagan, G.; Mancini, R. C.; Murphy, T. J.; Stoeckl, C.; Yaakobi, B.; Benage, J. F.

    2014-10-01

    In ICF, the impact on symmetry of low mode drive non-uniformity is amplified by high convergence. Measurements have shown low mode areal density variation, however, direct impact of low modes on fuel volume has remained undemonstrated. We suggest our images provide first evidence of symmetry loss at the fuel-shell interface. The experiments use direct-drive spherical implosions (Omega). The inner 100 nm layer of the plastic shell is doped with diagnostic Ti to obtain information about interface position, temperature and density. Measurement is made at onset of deceleration at which time nuclear yield rate (NTD) and time resolved (SSCA) spectrum both are in agreement with 1-D prediction. Spectrally resolved images are obtained using the Multiple Monochromatic Imager, which combines a pinhole array with x-ray dispersive mirror and gated detector. Angle averaging of the limb-brightened image data also shows agreement with the 1D calculation. However, the 2D image shows ~20% brightness variations over modes 2-10. These modulations are discussed in context of predicted variations of interface position.

  16. LÓGICA DEL NEGOCIO DE LA EMPRESA EN UNA CAPA INTERMEDIA

    Directory of Open Access Journals (Sweden)

    Daymel Marrero Viñas

    2002-05-01

    Full Text Available

    El trabajo que se presenta sugiere dos maneras de afrontar el desarrollo de un sistema informativo para la empresa en un ambiente colaborativo. Teniendo en cuenta la dinámica actual y las necesidades de mantenimiento inmediato a los sistemas automatizados. Se comparan los modelos de dos y trescapas para la arquitectura cliente-servidor haciendo especial énfasis en las ventajas del modelo de tres capas por su facilidad de extensión a diferentes entornos de desarrollo de la aplicación cliente sin necesidad de grandes variaciones en los procesos de manipulación de los datos.

  17. Anti-diuretic factors in insects: the role of CAPA peptides.

    Science.gov (United States)

    Paluzzi, Jean-Paul V

    2012-05-01

    Insects have adapted to live in a wide variety of habitats and utilize an array of feeding strategies that present challenges to their ability to maintain osmotic balance. Regardless of the feeding strategy, water and ion levels within the haemolymph (insect blood) are maintained within a narrow range. This homeostasis involves the action of a variety of tissues, but is often chiefly regulated by the excretory system. Until recently, most research on the hormonal control of the excretory tissues has focused on factors known to have diuretic activities. In this mini-review, the current state of knowledge on anti-diuretic factors in insects will be discussed with a particular emphasis on the CAPA peptides in the blood-feeding Chagas' disease vector, Rhodnius prolixus.

  18. CONCENTRAÇÃO DE PARTÍCULAS MINERAIS FINAS E ULTRAFINAS POR ELETROFLOTAÇÃO

    Directory of Open Access Journals (Sweden)

    Everton Pedroza Santos

    2011-12-01

    Full Text Available A baixa recuperação na flotação de partículas minerais finas e ultrafinas continua sendo um dos principais desafios da área de processamento mineral. As técnicas emergentes existentes para o aumento da recuperação destas partículas são baseadas em novos conceitos de otimização da “captura” de partículas por bolhas, através do aumento da probabilidade de colisão bolha-partícula, injetando bolhas médias (100 – 600 μm e pequenas (< 100 μm na célula de flotação. Dentre as técnicas existentes para a geração de bolhas pequenas, estão a flotação por ar dissolvido (FAD e a eletroflotação (EF. Na EF são empregadas microbolhas de oxigênio e hidrogênio, geradas a partir da decomposição eletrolítica da água. Estas bolhas, com diâmetros variando entre 20 a 50 µm, são menores que as obtidas na FAD. As unidades de EF são pequenas e compactas e apresentam baixos custos de manutenção e funcionamento, quando comparadas a outros processos de flotação. Diversos estudos têm demonstrado a viabilidade do processo de EF aplicado ao tratamento de águas e de efluentes industriais, porém poucos estudos abordam a utilização desta técnica na área de processamento mineral. Este trabalho apresenta uma revisão da literatura sobre a utilização da EF aplicada ao tratamento de partículas minerais finas e ultrafinas.

  19. Systematic Literature Review on ICF From 2001 to 2013 in the Nordic Countries Focusing on Clinical and Rehabilitation Context

    DEFF Research Database (Denmark)

    Maribo, Thomas; Petersen, Kirsten Schultz; Handberg, Charlotte;

    2016-01-01

    We present a systematic review on International Classification of Functioning, Disability and Health (ICF) used in the Nordic countries from 2001 through 2013, describing and quantifying the development in utilization of ICF, and describe the extent to which the different components of the ICF have...... included papers were published in the period 2011 - 2013. There was an increase in ICF-relevant papers from 2001 to 2013, especially in the categories "clinical and/or rehabilitation contexts" and "non-clinical contexts". The most represented focus areas were neurology, musculoskeletal, and work-related...

  20. Punção Aspirativa por Agulha Fina Orientada por Ultra-Sonografia em Lesões Não-palpáveis

    OpenAIRE

    2001-01-01

    Objetivo: correlacionar os achados citológicos obtidos por punção com agulha fina dirigida pela ultra-sonografia de lesões não-palpáveis da mama, císticas ou sólidas, os aspectos ultra-sonográficos e os respectivos resultados histopatológicos das lesões que foram submetidas a cirurgia. Métodos: foram analisadas 617 lesões não-palpáveis visualizadas ao ultra-som. Realizou-se a punção aspirativa por agulha fina (PAAF) orientada pela ultra-sonografia, com análise citológica do material, diferenc...

  1. Feasibility of the Dutch ICF Activity Inventory: a pilot study

    Directory of Open Access Journals (Sweden)

    van Nispen Ruth MA

    2010-11-01

    Full Text Available Abstract Background Demographic ageing will lead to increasing pressure on visual rehabilitation services, which need to be efficiently organised in the near future. The Dutch ICF Activity Inventory (D-AI was developed to assess the rehabilitation needs of visually impaired persons. This pilot study tests the feasibility of the D-AI using a computer-assisted telephone interview. Methods In addition to the regular intake, the first version of the D-AI was assessed in 20 patients. Subsequently, patients and intake assessors were asked to fill in an evaluation form. Based on these evaluations, a new version of the D-AI was developed. Results Mean administration time of the D-AI was 88.8 (± 41.0 minutes. Overall, patients and assessors were positive about the D-AI assessment. However, professionals and 60% of the patients found the administration time to be too long. All included items were considered relevant and only minor adjustments were recommended. Conclusion The systematic character of the revised D-AI will prevent topics from being overlooked and indicate which needs have the highest priority from a patient-centred perspective. Moreover, ongoing assessment of the D-AI will enhance evaluation of the rehabilitation process. To decrease administration time, in the revised D-AI only the top priority goals will be fully assessed. Using the D-AI, a rehabilitation plan based on individual needs can be developed for each patient. Moreover, it enables better evaluation of the effects of rehabilitation. A larger validation study is planned.

  2. The ICF Status and Plans in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Moses, E; Miller, G; Kauffman, R

    2005-10-12

    The United States continues to maintain its leadership in ICF as it moves toward the goal of ignition. The flagship of the program is the National Ignition Facility (NIF) presently under construction at LLNL. Experiments had begun on the first four beams of the National Ignition Facility just at the time of the last IFSA Conference. Several new successful campaigns have been conducted since then in planar hydrodynamics and hohlraums as well as activating the VISAR diagnostic for equation of state experiments. Highlights of these results will be reviewed. Presently, the four beam experimental capability has been suspended while the first eight beams are being installed as the first step in building out the project. Meanwhile, much progress has been made in developing ignition designs for using NIF. An array of designs having several ablator materials have been shown computationally to ignite with energies ranging from the design energy to as low as 1 MJ of laser energy. Alternative direct drive designs in the NIF indirect drive configuration have been developed by LLE. This wide array of design choices has increased the chance of achieving ignition sooner on the facility. Plans are now being developed to begin an ignition experimental campaign on NIF in 2010, a little over a year after completion of the facility. Other US facilities are also implementing improved capabilities. Petawatt lasers are now under construction at the University of Rochester and Sandia National Laboratory. The Z pulsed power machine at Sandia National Laboratory is being refurbished to improve its performance. The ongoing research program at the OMEGA laser at the University of Rochester and the Z machine at Sandia National Laboratory as well as at the Nike, Trident and Janus lasers remain strong, performing experiments supporting the NIF ignition plan and direct drive ignition. There also is an active program in the broader field of high energy density science on these facilities. These

  3. [Relevance of personal contextual factors of the ICF for use in practical social medicine and rehabilitation].

    Science.gov (United States)

    Grotkamp, S; Cibis, W; Bahemann, A; Baldus, A; Behrens, J; Nyffeler, I D; Echterhoff, W; Fialka-Moser, V; Fries, W; Fuchs, H; Gmünder, H P; Gutenbrunner, C; Keller, K; Nüchtern, E; Pöthig, D; Queri, S; Rentsch, H P; Rink, M; Schian, H-M; Schian, M; Schmitt, K; Schwarze, M; Ulrich, P; von Mittelstaedt, G; Seger, W

    2014-03-01

    Personal contextual factors play an essential part in the model of the International Classification of Functioning, Disability and Health (ICF). The WHO has not yet classified personal factors for global use although they impact on the functioning of persons positively or negatively. In 2010, the ICF working group of the German Society of Social Medicine and Prevention (DGSMP) presented a proposal for the classification of personal factors into 72 categories previously arranged in 6 chapters. Now a positioning paper has been added in order to stimulate a discussion about the fourth component of the ICF, to contribute towards a broader and common understanding about the nature of personal factors and to incite a dialogue among all those involved in health care as well as those people with or with-out health problems in order to gain a comprehensive perspective about a person's condition.

  4. When Shape Matters: correcting the ICFs to derive the chemical abundances of bipolar and elliptical PNe

    CERN Document Server

    Goncalves, D R; Morisset, C; Barlow, M; Ercolano, B

    2011-01-01

    The extraction of chemical abundances of ionised nebulae from a limited spectral range is usually hampered by the lack of emission lines corresponding to certain ionic stages. So far, the missing emission lines have been accounted for by the ionisation correction factors (ICFs), constructed under simplistic assumptions like spherical geometry by using 1-D photoionisation modelling. In this contribution we discuss the results (Goncalves et al. 2011, in prep.) of our ongoing project to find a new set of ICFs to determine total abundances of N, O, Ne, Ar, and S, with optical spectra, in the case of non-spherical PNe. These results are based on a grid of 3-D photoionisation modelling of round, elliptical and bipolar shaped PNe, spanning the typical PN luminosities, effective temperatures and densities. We show that the additional corrections --to the widely used Kingsburgh and Barlow (1994) ICFs-- are always higher for bipolars than for ellipticals. Moreover, these additional corrections are, for bipolars, up to:...

  5. La formación Capas Rojas: caracterización y génesis

    Directory of Open Access Journals (Sweden)

    Molina, J. M.

    1999-04-01

    Full Text Available The characteristics (lithofacies, biofacies, age, thickness, vertical and lateral relations, etc., and significance of the Capas Rojas Formation (Upper Cretaceous-Eocene are analysed. This formation crops out widely in the Subbetic (External Zones of the Betic Cordillera. The Capas Rojas Formation presents a great uniformity in the wide sectors of this cordillera and has its equivalent in facies and age, in the Scaglia Rossa Formation of the Apennines and southern Alps and also in equally analogous formations in other Alpine Mediterranean domains. From the available sedimentological and paleoecological data, mainly from the macrofossils (isolated rudists and echinoids content and from the ichnofacies analysis, it is concluded that its deposition took place in a hemipelagic marine environment with a moderate depth (a few hundreds of metres during a long interval of time (40-50 Ma with a very low sedimentation rate (a few millimetres per thousand years. From the analysis of the evolution of the continental margin in which was deposited, and of their equivalents in other Alpine domains, is deduced that the beginning of its deposition recorded the end of the differentiation in troughs and swells of these passive margins in the advanced stages of the rifting, so that this unit, in wide sector of the basin covered areas with an irregular topography in the bottom, mainly controlled by faults and slowly leveled them.Se analizan las características (litofacies, biofacies, edad, potencia, etc. de la Formación Capas Rojas (Cretácico superior-Eoceno que aflora extensamente en el Subbético, dentro de las Zonas Externas de la Cordillera Bética. Esta formación presenta una gran uniformidad de facies en amplios sectores de la cordillera y tiene su equivalente, en facies y en edad, en la Formación Scaglia Rossa de los Apeninos del centro de Italia y de los Alpes meridionales y en formaciones igualmente análogas en otros dominios alpinos mediterráneos. A

  6. Identification of relevant ICF (International Classification of Functioning, Disability and Health) categories in lymphedema patients: A cross-sectional study

    NARCIS (Netherlands)

    Viehoff, P.B.; Potijk, F.; Damstra, R.J.; Heerkens, Y.F.; Ravensberg, C.D. van; Berkel, D.M. van; Neumann, H.A.

    2015-01-01

    BACKGROUND: To describe functioning and health of lymphedema patients and to identify their most common problems using the International Classification of Functioning, Disability and Health (ICF) as part of the preparatory studies for the development of ICF Core Sets for lymphedema. METHODS: Cross-s

  7. Identification of relevant ICF (International Classification of Functioning, Disability and Health) categories in lymphedema patients: A cross-sectional study

    NARCIS (Netherlands)

    P.B. Viehoff (Peter); F. Potijk; R.J. Damstra (Robert); Y.F. Heerkens (Yvonne); C.D. van Ravensberg (Dorine); D.M. Van Berkel; H.A.M. Neumann (Martino)

    2015-01-01

    textabstractBackground. To describe functioning and health of lymphedema patients and to identify their most common problems using the International Classification of Functioning, Disability and Health (ICF) as part of the preparatory studies for the development of ICF Core Sets for lymphedema.Metho

  8. Core science and technology development plan for indirect-drive ICF ignition. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Powell, H.T.; Kilkenny, J.D. [eds.

    1995-12-01

    To define the development work needed to support inertial confinement fusion (ICF) program goals, the authors have assembled this Core Science and Technology (CS and T) Plan that encompasses nearly all science research and technology development in the ICF program. The objective of the CS and T Plan described here is to identify the development work needed to ensure the success of advanced ICF facilities, in particular the National Ignition Facility (NIF). This plan is intended as a framework to facilitate planning and coordination of future ICF programmatic activities. The CS and T Plan covers all elements of the ICF program including laser technology, optic manufacturing, target chamber, target diagnostics, target design and theory, target components and fabrication, and target physics experiments. The CS and T Plan has been divided into these seven different technology development areas, and they are used as level-1 categories in a work breakdown structure (WBS) to facilitate the organization of all activities in this plan. The scope of the CS and T Plan includes all research and development required to support the NIF leading up to the activation and initial operation as an indirect-drive facility. In each of the CS and T main development areas, the authors describe the technology and issues that need to be addressed to achieve NIF performance goals. To resolve all issues and achieve objectives, an extensive assortment of tasks must be performed in a coordinated and timely manner. The authors describe these activities and present planning schedules that detail the flow of work to be performed over a 10-year period corresponding to estimated time needed to demonstrate fusion ignition with the NIF. Besides the benefits to the ICF program, the authors also discuss how the commercial sector and the nuclear weapons science may profit from the proposed research and development program.

  9. 制药企业纠正和预防措施(CAPA)体系的建立

    Institute of Scientific and Technical Information of China (English)

    郑士辉; 娄玲珠

    2011-01-01

    目的 利用CAPA原则对制药企业的产品质量问题进行防患与未然.方法 选择合适的功能模块,建立和维护一个有效的纠正和预防措施(CAPA)控制体系.结果 纠正和预防措施(CAPA)体系是质量管理体系的一个核心组成部分,可以实现产品质量的持续改进.结论 一套切实可行的CA-PA流程将能有效地帮助制药企业对质量体系进行管理.

  10. The role of experimental science in ICF -- examples from X-ray diagnostics and targets

    Science.gov (United States)

    Kilkenny, J. D.

    2016-10-01

    The USA Inertial Confinement Fusion (ICF) Program evolved from the Nuclear Test Program which had restricted shot opportunities for experimentalists to develop sophisticated experimental techniques. In contrast the ICF program in the US was able to increase the shot availability on its large facilities, and develop sophisticated targets and diagnostics to measure and understand the properties of the high energy density plasmas (HEDP) formed. Illustrative aspects of this evolution at Lawrence Livermore National Laboratory (LLNL), with examples of the development of diagnostics and target fabrication are described.

  11. The Development of a Framework for Target Diagnostic Centralized Control System (TDCCS) in ICF Experiments

    Science.gov (United States)

    Zhang, Chi; Wang, Jian; Yu, Xiaoqi; Yang, Dong

    2008-02-01

    A framework for target diagnostic centralized control system (TDCCS) in inertial confinement fusion (ICF) experiment has been developed. The developed framework is based on the common object request broker architecture (CORBA) standard and part of the concept from the ICFRoot (a framework based on ROOT for ICF experiments) framework design. This framework is of a component architecture, including a message bus, command executer, status processor, parser and proxy. To test the function of the framework, a simplified prototype of the TDCCS has been developed as well.

  12. COMPORTAMIENTO ESTACIONAL DE LA CAPA DE MEZCLA MARINA EN LA REGIÓN NORTE DEL GOLFO DE CALIFORNIA

    Directory of Open Access Journals (Sweden)

    Emilio Palacios Hernández

    2016-01-01

    Full Text Available Se realiza l a descripción de la profundidad de la capa de mezcla marina superficial (PCM en la Región Norte del Golfo de California (RNGC, utilizando datos hidrográficos obtenidos en 17 cruceros oceanográficos desde 1971 hasta 1996. La profundidad de la capa se estima directament e de los perfiles de densidad . El promedio de distribución espacial muestra un máximo bien definido en la salida del canal de Ballenas y un mínimo en las costas de Sonora y de Baja California donde la capa de mezcla no puede ser más profunda ya que son lugares demasiado someros y la mez cla cubre toda la profundidad del lugar. La PCM en la RNGC tiene una señal estacional con una transición en abril y otra en octubre. En verano (ju l io a septiembre la profundidad de la capa de mezcla se caracteriza por ser demasiado so mera mostrando un máx imo de 48 m y un mínimo de 10 m, mientras que en invierno (enero a marz o se prof undiza a un máximo de hasta 100 m . Existe una anomalía en el evento de ma rzo de 1973 la cual muestra estima ciones de PCM mayores que las esperadas, estas anomalías al parecer son causadas por el evento interanual El Niño (EN 1972 - 1973, ya que no se pudo encontrar evidencia similar del fenómeno en otros marzos.

  13. Performances musicais no rock brasileiro dos anos 1970, por meio de análises de capas de discos

    Directory of Open Access Journals (Sweden)

    Victor H. de Resende

    2016-06-01

    Full Text Available O presente artigo tem como finalidade demonstrar algumas performances de grupos de rock brasileiro dos anos 1970, por meio de análises das capas de discos selecionadas. Defende-se a hipótese de que as capas, as contracapas e os encartes de discos de rock são elementos importantes de performance e de estética do gênero. Conforme será visto, em alguns encartes selecionados, é possível perceber o processo de trabalho dos músicos. Em textos de alguns encartes também se visualizam as propostas dos grupos, bem como suas estratégias para vender seus LPs e angariar fãs. Nas capas também se percebem, por meio das imagens, as várias produções e propostas estéticas dos artistas de rock nos anos 70. Para as análises, aqui propostas, tomam-se as bandas Casa das Máquinas, O Terço e o trio Sá, Rodrix & Guarabyra.

  14. High-performance nanocrystalline NdFeB magnets by CAPA process

    Energy Technology Data Exchange (ETDEWEB)

    Kim, H.T. [Tesla Co., Ltd., 340-1 Songsan-Ri, Yanggam-Myeon, Hwasung City, Gyeonggi-Do, 445-396 (Korea, Republic of)]. E-mail: htkim@gotesla.com; Kim, Y.B. [Korea Research Institute Standards and Sciences, 305-600, Daejeon (Korea, Republic of); Jeon, J.W. [Chonbuk National University, 756-356, Jeonju (Korea, Republic of); Jang, I.H. [Tesla Co., Ltd., 340-1 Songsan-Ri, Yanggam-Myeon, Hwasung City, Gyeonggi-Do, 445-396 (Korea, Republic of); Kapustin, G.A. [RRC Kurchatov Institute, Moscow, 123182 (Russian Federation); Kim, H.S. [Chonbuk National University, 756-356, Jeonju (Korea, Republic of)

    2006-09-15

    The anisotropic NdFeB magnets were prepared from the melt-spun isotropic powders by CAPA process. The precursor isotropic magnet shows the uniform magnetic properties according to the overall position in the magnet. In the case of the anisotropic magnet, the outer position shows higher remanence and energy product compared to the center position. The magnetic properties of the anisotropic magnet obtained from Nd{sub 14}Fe{sub 80}B{sub 6} powders are B{sub r}=15kG, {sub i}H{sub c}=4.1kOe and BH{sub max}=36MGOe. In the case of addition of Zn to Nd{sub 14}Fe{sub 80}B{sub 6} powders, the energy product increased because of the improved coercivity. The magnetic properties of the Zn-added magnet are B{sub r}=14.5kG, {sub i}H{sub c}=9.7kOe and BH{sub max}=52MGOe. The Zn addition is effective to depress Nd{sub 2}Fe{sub 14}B grain growth of the interparticle regions during plastic deformation.

  15. Comportamiento de las capas deformadas por rodadura en los equipos de laboreo minero

    Directory of Open Access Journals (Sweden)

    I. Rodríguez

    2008-06-01

    Full Text Available En este trabajo se estudió el comportamiento de las capas deformadas por el desgaste en los pasadores de esteras en los equipos de laboreo minero. Los datos experimentales se obtuvieron utilizando pasadores desgastados y deformes. Las muestras se cortaron bajo refrigeración constante para evitar cambio en su estructura. Para el análisis de la composición química se utilizó un espectrómetro cuántico. Además, se empleó el método de microscopía óptica para analizar el efecto del endurecimiento por deformación utilizando los perfiles de microdureza. Se encontró que los pasadores tiene una composición química de un acero tipo AISI 1045. Además, se determinó que poseen una microestructura martensítica, la cuál disminuye debido a la deformación por el efecto de la rodadura.

  16. Differential sorting and packaging of capa-gene related products in an insect.

    Science.gov (United States)

    Pollák, Edit; Eckert, Manfred; Molnár, László; Predel, Reinhard

    2005-01-03

    A unique costorage of neuropeptides was recently found in the abdominal perisympathetic organs (PSOs) of the American cockroach, Periplaneta americana. Having specific antisera directed against all peptides belonging to this neurosecretory system, we examined the sorting of PSO-peptides in the soma of the median neurosecretory cells of abdominal ganglia by using immunoelectron microscopic double stainings. The data indicate that all six abundant neuropeptides of this neurohormonal system, which includes three capa-gene related products, are primarily incorporated into separate vesicles. These vesicles fuse with each other in the cytoplasm and become translucent on their way to the axon hillock. By means of light microscopy and MALDI-TOF mass spectrometry, an identical population of neuropeptides was found in interneurons of the brain. As revealed by subsequent immunoelectron microscopic analysis, the peptides of these cells are separately packed into dense core vesicles but do not fuse with each other. Thus, hitherto unknown cell-type-specific sorting mechanisms occur in neurosecretory cells and interneurons, respectively.

  17. Evidence for the validity of the Children's Attraction to Physical Activity questionnaire (CAPA) with young children.

    Science.gov (United States)

    Rose, Elizabeth; Larkin, Dawne; Hands, Beth; Howard, Barbara; Parker, Helen

    2009-09-01

    Attraction to physical activity is important to an individual's intrinsic motivation to engage in play, games and sports. While there are instruments designed to measure attraction to physical activity in middle childhood years, the lack of authentic measures in young children has impeded research in this area. In this study we sought to address the validity of a scale to tap young children's attraction to physical activity. Evidence for validity was based on internal consistency, content analysis, and factor structure. Australian school children (180 boys and 154 girls) from school year two, aged 6-8 years, were individually administered a modified version of the Children's Attraction to Physical Activity Scale (CAPA) [Brustad RJ. Who will go out to play? Parental and psychological influences on children's attraction to physical activity. Pediatr Exerc Sci 1993;5:210-23; Brustad RJ. Attraction to physical activity in urban school children: parental socialization and gender influences. Res Q Exerc Sport 1996;67:316-23]. The results indicated that internal consistency was acceptable for most of the subscales when negative statements were excluded from the analyses. Factor analysis revealed that the liking of games and sports, liking of physical exertion and exercise, and the importance of exercise subscales were more robust. Second order factor analysis indicated that the overall construct of attraction to physical activity was viable in this age group. With some modifications, the scale appears to provide a valid approach to the measurement of attraction to physical activity in young children.

  18. Can we improve service efficiency in CAMHS using the CAPA approach without reducing treatment effectiveness?

    Science.gov (United States)

    Fuggle, Peter; McHugh, Annie; Gore, Lucy; Dixon, Emily; Curran, Daniel; Cutinha, Darren

    2016-06-01

    Health-care systems are under increasing pressure to deliver more care with similar or even less resources and there is concern that this may be achieved at the cost of reduced clinical effectiveness. In Child and Adolescent Mental Health Services (CAMHS), the Choice and Partnership Approach (CAPA) has been widely adopted as a way of increasing the efficient use of limited service resources. Some evaluations have reported increased patient flow and reduced waiting times, but it remains unknown whether such changes have been achieved at a cost of clinical effectiveness. This article describes a pragmatic multi-method evaluation of a CAMHS service reporting service outcomes (client satisfaction, waiting times, and patient flow) and clinical outcomes (clinician-rated clinical outcomes and goals achieved by families). Results showed improved service outcomes (high levels of client satisfaction and reduced waiting times) and an increase in patient flow (49 cases increased to 72 cases over an equivalent time period). Clinical outcomes showed no reduction in effectiveness and a significant improvement against the agreed goals of the intervention. The evaluation suggested that a well-structured goal-focused patient flow system may improve services by increasing patient flow while maintaining high satisfaction levels, without negatively impacting clinical effectiveness.

  19. High-performance nanocrystalline NdFeB magnets by CAPA process

    Science.gov (United States)

    Kim, H. T.; Kim, Y. B.; Jeon, J. W.; Jang, I. H.; Kapustin, G. A.; Kim, H. S.

    2006-09-01

    The anisotropic NdFeB magnets were prepared from the melt-spun isotropic powders by CAPA process. The precursor isotropic magnet shows the uniform magnetic properties according to the overall position in the magnet. In the case of the anisotropic magnet, the outer position shows higher remanence and energy product compared to the center position. The magnetic properties of the anisotropic magnet obtained from Nd 14Fe 80B 6 powders are B=15 kG, iH=4.1 kOe and BH=36 MG Oe. In the case of addition of Zn to Nd 14Fe 80B 6 powders, the energy product increased because of the improved coercivity. The magnetic properties of the Zn-added magnet are B=14.5 kG, iH=9.7 kOe and BH=52 MG Oe. The Zn addition is effective to depress Nd 2Fe 14B grain growth of the interparticle regions during plastic deformation.

  20. Analyses in support of the Laboratory Microfusion Facility and ICF commercial reactor designs

    Energy Technology Data Exchange (ETDEWEB)

    Meier, W.R.; Monsler, M.J.

    1988-12-28

    Our work on this contract was divided into two major categories; two thirds of the total effort was in support of the Laboratory Microfusion Facility (LMF), and one third of the effort was in support of Inertial Confinement Fusion (ICF) commercial reactors. This final report includes copies of the formal reports, memoranda, and viewgraph presentations that were completed under this contract.

  1. Inertial confinement fusion. 1995 ICF annual report, October 1994--September 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    Lawrence Livermore National Laboratory`s (LLNL`s) Inertial Confinement Fusion (ICF) Program is a Department of Energy (DOE) Defense Program research and advanced technology development program focused on the goal of demonstrating thermonuclear fusion ignition and energy gain in the laboratory. During FY 1995, the ICF Program continued to conduct ignition target physics optimization studies and weapons physics experiments in support of the Defense Program`s stockpile stewardship goals. It also continued to develop technologies in support of the performance, cost, and schedule goals of the National Ignition Facility (NIF) Project. The NIF is a key element of the DOE`s Stockpile Stewardship and Management Program. In addition to its primary Defense Program goals, the ICF Program provides research and development opportunities in fundamental high-energy-density physics and supports the necessary research base for the possible long-term application to inertial fusion energy (IFE). Also, ICF technologies have had spin-off applications for industrial and governmental use. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  2. A Conceptual Definition of Vocational Rehabilitation Based on the ICF : building a shared global model

    NARCIS (Netherlands)

    Escorpizo, Reuben; Reneman, Michiel F.; Ekholm, Jan; Fritz, Julie; Krupa, Terry; Marnetoft, Sven-Uno; Maroun, Claude E.; Guzman, Julietta Rodriguez; Suzuki, Yoshiko; Stucki, Gerold; Chan, Chetwyn C. H.

    2011-01-01

    Background The International Classification of Functioning, Disability and Health (ICF) is a conceptual framework and classification system by the World Health Organization (WHO) to understand functioning. The objective of this discussion paper is to offer a conceptual definition for vocational reha

  3. LANL Q2 2016 Quarterly Progress Report. Science Campaign and ICF

    Energy Technology Data Exchange (ETDEWEB)

    Douglas, Melissa Rae [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-04-07

    This progress report includes highlights for the Science Campaign and ICF about Advanced Certification and Assessment Methodologies, Implosion Hydrodynamics (C-1, SCE), Materials and Nuclear Science (C-1, C-2), Capabilities for Nuclear Intelligence, and High Energy Density Science (C-1, C-4, C-10). Upcoming meetings, briefings, and experiments are then listed for April and May.

  4. Development of the Data Processing and Analysis System Framework for ICF Experiments

    Institute of Scientific and Technical Information of China (English)

    Yang Dong; Yu Xiaoqi; Zhang Chi

    2005-01-01

    An idea is presented about the development of a data processing and analysis system for ICF experiments, which is based on an object oriented framework. The design and preliminary implementation of the data processing and analysis framework based on the ROOT system have been completed. Software for unfolding soft X-ray spectra has been developed to test the functions of this framework.

  5. 42 CFR 442.40 - Availability of FFP during appeals for ICFs/MR.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Availability of FFP during appeals for ICFs/MR. 442... INTERMEDIATE CARE FACILITIES FOR THE MENTALLY RETARDED Provider Agreements § 442.40 Availability of FFP during..., and effective date—(1) Scope. This section sets forth the extent of FFP in State Medicaid payments...

  6. Disability and Functional Profiles of Patients with Myasthenia Gravis Measured with ICF Classification

    Science.gov (United States)

    Leonardi, Matilde; Raggi, Alberto; Antozzi, Carlo; Confalonieri, Paolo; Maggi, Lorenzo; Cornelio, Ferdinando; Mantegazza, Renato

    2009-01-01

    The objective of this study is to describe functional profiles of patients with myasthenia gravis (MG), and the relationships among symptoms, activities and environmental factors (EF), by using WHO's International Classification of Functioning Disability and Health (ICF). Patients were consecutively enrolled at the Besta Institute of Milan, Italy.…

  7. The development and application of advanced analytical methods to commercial ICF reactor chambers. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Cousseau, P.; Engelstad, R.; Henderson, D.L. [and others

    1997-10-01

    Progress is summarized in this report for each of the following tasks: (1) multi-dimensional radiation hydrodynamics computer code development; (2) 2D radiation-hydrodynamic code development; (3) ALARA: analytic and Laplacian adaptive radioactivity analysis -- a complete package for analysis of induced activation; (4) structural dynamics modeling of ICF reactor chambers; and (5) analysis of self-consistent target chamber clearing.

  8. Site support program plan for ICF Kaiser Hanford Company, Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    This document is the general administrative plan implemented by the Hanford Site contractor, ICF Kaiser Hanford Company. It describes the mission, administrative structure, projected staffing, to be provided by the contractor. The report breaks out the work responsibilities within the different units of the company, a baseline schedule for the different groups, and a cost summary for the different operating units.

  9. Disability and Profiles of Functioning of Patients with Parkinson's Disease Described with ICF Classification

    Science.gov (United States)

    Raggi, Alberto; Leonardi, Matilde; Ajovalasit, Daniela; Carella, Francesco; Soliveri, Paola; Albanese, Alberto; Romito, Luigi

    2011-01-01

    The objective of this study was to describe the functional profiles of patients with Parkinson's disease (PD), and the relationships between impairment in body functions, limitations in activities, and environmental factors, using the World Health Organization's International Classification of Functioning, Disability, and Health (ICF). Patients…

  10. Use of The International Classification of Functioning, Disability and Health (ICF as a conceptual framework and common language for disability statistics and health information systems

    Directory of Open Access Journals (Sweden)

    Kostanjsek Nenad

    2011-05-01

    Full Text Available Abstract A common framework for describing functional status information is needed in order to make this information comparable and of value. The World Health Organization’s International Classification of Functioning, Disability and Health (ICF, which has been approved by all its member states, provides this common language and framework. The article provides an overview of ICF taxonomy, introduces the conceptual model which underpins ICF and elaborates on how ICF is used at population and clinical level. Furthermore, the article presents key features of the ICF tooling environment and outlines current and future developments of the classification.

  11. Distribución de la biomasa y densidad de raíces finas en una gradiente sucesional de bosques en la Zona Norte de Costa Rica

    OpenAIRE

    Jiménez-Rodríguez, César; Instituto Tecnológico de Costa Rica, Escuela de Ingeniería Forestal; Cartago, Costa Rica; Arias-Aguilar, Dagoberto; Instituto Tecnológico de Costa Rica, Escuela de Ingeniería Forestal; Cartago, Costa Rica

    2012-01-01

    En este estudio se evaluó la distribución de la biomasa radical, el índice de área radical (RAI) y la densidad longitudinal (RLD) de raíces finas (< 5 mm) en una gradiente sucesional de bosques húmedos tropicales en la zona de Florencia de San Carlos, Costa Rica. La variación de estos parámetros se evaluó en función de la profundidad del suelo y del estado sucesional.La biomasa radical, al igual que el RAI y el RLD, disminuyen conforme aumenta la profundidad en el perfil y coincide con los...

  12. Towards an ICF core set for ADHD: a worldwide expert survey on ability and disability.

    Science.gov (United States)

    de Schipper, Elles; Mahdi, Soheil; Coghill, David; de Vries, Petrus J; Gau, Susan Shur-Fen; Granlund, Mats; Holtmann, Martin; Karande, Sunil; Levy, Florence; Almodayfer, Omar; Rohde, Luis; Tannock, Rosemary; Bölte, Sven

    2015-12-01

    This is the second in a series of four empirical studies designed to develop International Classification of Functioning, Disability and Health (ICF and Children and Youth version, ICF-CY) core sets for attention deficit hyperactivity disorder (ADHD). The objective of this stage was to gather the opinions from international experts on which ability and disability concepts were considered relevant to functioning in ADHD. An email-based survey was carried out amongst international experts in ADHD. Relevant functional ability and disability concepts were extracted from their responses and linked to the ICF/-CY categories by two independent researchers using a standardised linking procedure. 174 experts from 11 different disciplines and 45 different countries completed the survey. Meaningful concepts identified in their responses were linked to 185 ICF/-CY categories. Of these, 83 categories were identified by at least 5 % of the experts and considered the most relevant to ADHD: 30 of these were related to Body functions (most identified: attention functions, 85 %), 30 to Activities and Participation (most identified: school education, 52 %), 20 to Environmental factors (most identified: support from immediate family, 61 %), and 3 to Body structures (most identified: structure of brain, 83 %). Experts also provided their views on particular abilities related to ADHD, naming characteristics such as high-energy levels, flexibility and resiliency. Gender differences in the expression of ADHD identified by experts pertained mainly to females showing more internalising (e.g. anxiety, low self-esteem) and less externalising behaviours (e.g. hyperactivity), leading to a risk of late- and under-diagnosis in females. Results indicate that the impact of ADHD extends beyond the core symptom domains, into all areas of life and across the lifespan. The current study in combination with three additional preparatory studies (comprehensive scoping review, focus groups, clinical study

  13. Genome-Wide DNA Methylation Analysis Identifies Novel Hypomethylated Non-Pericentromeric Genes with Potential Clinical Implications in ICF Syndrome.

    Directory of Open Access Journals (Sweden)

    L Simo-Riudalbas

    Full Text Available Immunodeficiency, centromeric instability and facial anomalies syndrome (ICF is a rare autosomal recessive disease, characterized by severe hypomethylation in pericentromeric regions of chromosomes (1, 16 and 9, marked immunodeficiency and facial anomalies. The majority of ICF patients present mutations in the DNMT3B gene, affecting the DNA methyltransferase activity of the protein. In the present study, we have used the Infinium 450K DNA methylation array to evaluate the methylation level of 450,000 CpGs in lymphoblastoid cell lines and untrasformed fibroblasts derived from ICF patients and healthy donors. Our results demonstrate that ICF-specific DNMT3B variants A603T/STP807ins and V699G/R54X cause global DNA hypomethylation compared to wild-type protein. We identified 181 novel differentially methylated positions (DMPs including subtelomeric and intrachromosomic regions, outside the classical ICF-related pericentromeric hypomethylated positions. Interestingly, these sites were mainly located in intergenic regions and inside the CpG islands. Among the identified hypomethylated CpG-island associated genes, we confirmed the overexpression of three selected genes, BOLL, SYCP2 and NCRNA00221, in ICF compared to healthy controls, which are supposed to be expressed in germ line and silenced in somatic tissues.In conclusion, this study contributes in clarifying the direct relationship between DNA methylation defect and gene expression impairment in ICF syndrome, identifying novel direct target genes of DNMT3B. A high percentage of the DMPs are located in the subtelomeric regions, indicating a specific role of DNMT3B in methylating these chromosomal sites. Therefore, we provide further evidence that hypomethylation in specific non-pericentromeric regions of chromosomes might be involved in the molecular pathogenesis of ICF syndrome. The detection of DNA hypomethylation at BOLL, SYCP2 and NCRNA00221 may pave the way for the development of specific

  14. CapA, an autotransporter protein of Campylobacter jejuni, mediates association with human epithelial cells and colonization of the chicken gut.

    Science.gov (United States)

    Ashgar, Sami S A; Oldfield, Neil J; Wooldridge, Karl G; Jones, Michael A; Irving, Greg J; Turner, David P J; Ala'Aldeen, Dlawer A A

    2007-03-01

    Two putative autotransporter proteins, CapA and CapB, were identified in silico from the genome sequence of Campylobacter jejuni NCTC11168. The genes encoding each protein contain homopolymeric tracts, suggestive of phase variation mediated by a slipped-strand mispairing mechanism; in each case the gene sequence contained frameshifts at these positions. The C-terminal two-thirds of the two genes, as well as a portion of the predicted signal peptides, were identical; the remaining N-terminal portions were gene specific. Both genes were cloned and expressed; recombinant polypeptides were purified and used to raise rabbit polyclonal monospecific antisera. Using immunoblotting, expression of the ca.116-kDa CapA protein was demonstrated for in vitro-grown cells of strain NCTC11168, for 4 out of 11 recent human fecal isolates, and for 2 out of 8 sequence-typed strains examined. Expression of CapB was not detected for any of the strains tested. Surface localization of CapA was demonstrated by subcellular fractionation and immunogold electron microscopy. Export of CapA was inhibited by globomycin, reinforcing the bioinformatic prediction that the protein is a lipoprotein. A capA insertion mutant had a significantly reduced capacity for association with and invasion of Caco-2 cells and failed to colonize and persist in chickens, indicating that CapA plays a role in host association and colonization by Campylobacter. In view of this demonstrated role, we propose that CapA stands for Campylobacter adhesion protein A.

  15. Identification of ICF categories relevant for nursing in the situation of acute and early post-acute rehabilitation

    Directory of Open Access Journals (Sweden)

    Strobl Ralf

    2008-02-01

    Full Text Available Abstract Background The recovery of patients after an acute episode of illness or injury depends both on adequate medical treatment and on the early identification of needs for rehabilitation care. The process of early beginning rehabilitation requires efficient communication both between health professionals and the patient in order to effectively address all rehabilitation goals. The currently used nursing taxonomies, however, are not intended for interdisciplinary use and thus may not contribute to efficient rehabilitation management and an optimal patient outcome. The ICF might be the missing link in this communication process. The objective of this study was to identify the categories of the International Classification of Functioning, Disability and Health (ICF categories relevant for nursing care in the situation of acute and early post-acute rehabilitation. Methods First, in a consensus process, "Leistungserfassung in der Pflege" (LEP nursing interventions relevant for the situation of acute and early post-acute rehabilitation were selected. Second, in an integrated two-step linking process, two nursing experts derived goals of LEP nursing interventions from their practical knowledge and selected corresponding ICF categories most relevant for patients in acute and post-acute rehabilitation (ICF Core Sets. Results Eighty-seven percent of ICF Core Set categories could be linked to goals of at least one nursing intervention variable of LEP. The ICF categories most frequently linked with LEP nursing interventions were respiration functions, experience of self and time functions and focusing attention. Thirteen percent of ICF Core Set categories could not be linked with LEP nursing interventions. The LEP nursing interventions which were linked with the highest number of different ICF-categories of all were "therapeutic intervention", "patient-nurse communication/information giving" and "mobilising". Conclusion The ICF Core Sets for the acute

  16. Burning the DT-plasma with inert impurities and non-cryogenic ICF-target with solid fuel

    OpenAIRE

    Gus'kov S.Yu.; Il'in D.V.; Sherman V.E.

    2013-01-01

    The ignition criterion, ignition energy and gain of DT-plasma of ICF-target in the presence of impurities of light atoms such as beryllium, carbon and lithium at their arbitrary concentration are found. It is shown that the most promising type of non-cryogenic solid thermonuclear fuel is DT-hydride of beryllium (BeDT). It is suggested to apply the targets with such a fuel as: (1) Fast-ignited ICF-target at the ignition energy of 25–50 kJ and compression driver energy of 2–3 MJ; (2) ICF-target...

  17. Generación de capas de conversión con elementos de tierras raras sobre acero galvanizado

    Directory of Open Access Journals (Sweden)

    Arenas, M. A.

    2005-12-01

    Full Text Available Cerium conversion coatings are formed on commercial galvanized steel and a generation mechanism is suggested. The best conversion coatings were found using 10,000 ppm CeCl3·7H2O + 0,3 % vol. of H2O2 with a pH of 1.3. A cathodic potential, -100 mV versus corrosion potential, was applied during the treatment at a constant temperature of 43 °C. SEM micrographs have revealed a non uniform coating thickness between 1-2 μm. Polarization curves in 3.56 wt. % NaCl exhibited an inhibition power of about 94 % with respect to the galvanized steel. The proposed mechanism suggests that the Ce (III ions in the solution were oxidized by H2O2 to Ce (IV which then precipitated as CeO2. The applied voltage could cause a higher presence of Ce3+ in the film maybe due to an electroreduction process of cerium (IV in the film to cerium (III.

    En el presente trabajo, se desarrollan capas de conversión de cerio sobre un acero galvanizado comercial, proponiéndose un mecanismo de formación de las mismas. Las condiciones óptimas de generación de la capa se consiguieron empleando una disolución de 10.000 ppm de CeCl3·7H2O + 0,3 % vol. de H2O2 ajustando el pH a 1,3. A su vez, para mejorar la adherencia y reducir el tiempo de tratamiento se realizó, durante los 10 min del tratamiento, una activación potenciostática a -100 mV respecto al potencial de corrosión, manteniéndose la temperatura a 43 °C. El estudio del corte transversal de las muestras mediante microscopía electrónica de barrido reveló que las capas de cerio poseen un espesor no uniforme de 1-2 μm. Los resultados electroquímicos indicaron que las capas de cerio generadas ofrecían porcentajes de inhibición del orden del 94 % en cloruro sódico. Un posible mecanismo de formación de la capa de conversión sería que los iones de cerio (III en solución se

  18. capA, a cspA-like gene that encodes a cold acclimation protein in the psychrotrophic bacterium Arthrobacter globiformis SI55.

    Science.gov (United States)

    Berger, F; Normand, P; Potier, P

    1997-09-01

    By use of Arthrobacter globiformis SI55, a psychrotrophic bacterium capable of growth between -5 and +32 degrees C, we cloned and sequenced capA, a gene homologous to cspA encoding the major cold shock protein in Escherichia coli. The deduced protein sequence has a high level of identity with the sequences of other CspA-related proteins from various sources, and no particular residue or domain that could be specific to cold-adapted microorganisms emerged. We show that CapA was produced very rapidly following cold shock, but unlike its mesophilic counterparts, it was still expressed during prolonged growth at low temperature. Its synthesis is regulated at the translational level, and we showed that growth resumption following a temperature downshift correlated with CapA expression. Transient inhibitions in protein synthesis during the first stages of the cold shock response severely impaired the subsequent acclimation of A. globiformis SI55 to low temperature and delayed CapA expression. The cold shock response in A. globiformis SI55 is an adaptative process in which CapA may play a crucial role. We suggest that low-temperature acclimation is conditioned mainly by the ability of cells to restore an active translational machinery after cold shock in a process that may be different from that present in mesophiles.

  19. Modelo experimental de cultura primária de melanoma metastático por punção aspirativa de agulha fina

    Directory of Open Access Journals (Sweden)

    Oliveira Andrea Fernandes de

    2005-01-01

    Full Text Available OBJETIVO: Estabelecer um modelo experimental de cultura primária de melanoma metastático por punção aspirativa por agulha fina (PAAF. MÉTODOS: Duas culturas primárias de células de melanoma metastático através de PAAF foram desenvolvidas a partir de pacientes submetidos à excisão de lesões metastáticas e identificadas por imunohistoquímica utilizando os marcadores S-100 e MB-45, específicos para melanoma. RESULTADOS: O diagnóstico da cultura foi confirmado através da imunohistoquímica. A técnica oferece vantagens como pequena morbidade e invasibilidade, além do mais, a mesma lesão pode ser puncionada seqüencialmente durante o tratamento do doente. CONCLUSÃO: O estabelecimento de cultura primária de melanoma metastático a partir de punção aspirativa por agulha fina mostrou-se uma técnica viável.

  20. Health problems and disability in long-term sickness absence: ICF coding of medical certificates

    Directory of Open Access Journals (Sweden)

    Morgell Roland

    2011-11-01

    Full Text Available Abstract Background The purpose of this study was to test the feasibility of International Classification of Functioning, Disability and Health (ICF and to explore the distribution, including gender differences, of health problems and disabilities as reflected in long-term sickness absence certificates. Methods A total of 433 patients with long sick-listing periods, 267 women and 166 men, were included in the study. All certificates exceeding 28 days of sick-listing sent to the local office of the Swedish Social Insurance Administration of a municipality in the Stockholm area were collected during four weeks in 2004-2005. ICD-10 medical diagnosis codes in the certificates were retrieved and free text information on disabilities in body function, body structure or activity and participation were coded according to ICF short version. Results In 89.8% of the certificates there were descriptions of disabilities that readily could be classified according to ICF. In a reliability test 123/131 (94% items of randomly chosen free text information were identically classified by two of the authors. On average 2.4 disability categories (range 0-9 were found per patient; the most frequent were 'Sensation of pain' (35.1% of the patients, 'Emotional functions' (34.1%, 'Energy and drive functions' (22.4%, and 'Sleep functions' (16.9%. The dominating ICD-10 diagnostic groups were 'Mental and behavioural disorders' (34.4% and 'Diseases of the musculoskeletal system and connective tissue' (32.8%. 'Reaction to severe stress and adjustment disorders' (14.7%, and 'Depressive episode' (11.5% were the most frequent diagnostic codes. Disabilities in mental functions and activity/participation were more commonly described among women, while disabilities related to the musculoskeletal system were more frequent among men. Conclusions Both ICD-10 diagnoses and ICF categories were dominated by mental and musculoskeletal health problems, but there seems to be gender

  1. RESONANCIA ELECTRICA EN EL RANGO THETA (8) EN NEURONAS DE LA CAPA II DEL NUCLEO CORTICAL ANTERIOR DE LA AMIGDALA

    OpenAIRE

    2010-01-01

    El complejo de la amígdala participa en procesar información sensorial relevante desde el punto de vista emocional. La información sensorial olfativa entra desde el bulbo olfatorio (OB) a este complejo a través de la corteza olfatoria, la cual incluye los núcleos corticales de la amígdala. En ratas las neuronas mitrales del OB y aquellas de la capa II del núcleo cortical anterior (ACo) y la corteza periamigdaloide división medial (P A Cm) presentan oscilaciones intrínsecas del potencial de...

  2. RESONANCIA ELECTRICA EN EL RANGO THETA (0) EN NEURONAS DE LA CAPA II DEL NUCLEO CORTICAL ANTERIOR DE LA AMIGDALA

    OpenAIRE

    2010-01-01

    El complejo de la amígdala participa en procesar información sensorial relevante desde el punto de vista emocional. La información sensorial olfativa entra desde el bulbo olfatorio (OB) a este complejo a través de la corteza olfatoria, la cual incluye los núcleos corticales de la amígdala. En ratas las neuronas mitrales del OB y aquellas de la capa II del núcleo cortical anterior (ACo) y la corteza periamigdaloide división medial (P A Cm) presentan oscilaciones intrínsecas del ...

  3. Effect of initial conditions and Mach number on the Richtmyer-Meshkov instability in ICF like conditions

    Science.gov (United States)

    Rao, Pooja; She, Dan; Lim, Hyunkyung; Glimm, James

    2015-11-01

    The qualitative and quantitative effect of initial conditions (linear and non-linear) and high Mach number (1.3 and 1.45) is studied on the turbulent mixing induced by the Richtmyer-Meshkov instability in idealized ICF conditions. The Richtmyer-Meshkov instability seeds Rayleigh-taylor instabilities in ICF experiments and is one of the factors that contributes to reduced performance of ICF experiments. Its also found in collapsing cores of stars and supersonic combustion. We use the Stony Brook University code, FronTier, which is verified via a code comparison study against the AMR multiphysics code FLASH, and validated against vertical shock tube experiments done by the LANL Extreme Fluids Team. These simulations are designed as a step towards simulating more realistic ICF conditions and quantifying the detrimental effects of mixing on the yield.

  4. [ICF and social medicine evaluation of capability of gainful activity: is everything clear?--a discussion article].

    Science.gov (United States)

    Körner, M

    2005-08-01

    The ICF (International Classification of Functioning, Disability and Health) calls attention to the complexities associated with disturbances of health. The question raised is how the various constituents and the resulting network as defined by this Classification can gain importance for medical expertise under the statutory pension insurance scheme concerning work-related capacity. Possible variations of strategy are discussed: clinical intuition, algorithmic pathways, proved medical diagnostics, particular diagnostics of activity according to ICF. A genuine "silver bullet" is not in evidence thus far. It cannot be expected that diagnostics relating to a certain sector of the ICF will basically eclipse the rest. Future standards of medical expertise should specify as clearly as possible the impact of the diverse diagnostic findings on the assessment of work-related capacity. Framing emphasis in this way cannot be performed by the ICF on its own.

  5. Functioning in lymphedema from the patients' perspective using the International Classification of Functioning, Disability and health (ICF) as a reference

    NARCIS (Netherlands)

    Viehoff, P.B.; Gielink, P.D.; Damstra, R.J.; Heerkens, Y.F.; Ravensberg, C.D. van; Neumann, M.H.

    2015-01-01

    Abstract Purpose. To identify and quantify meaningful concepts in lymphedema from the patients' perspectives using the International Classification of Functioning, Disability and Health (ICF). Methods. Six focus group interviews in five different centers were organized, audiotaped, transcribed verba

  6. Health professionals identify components of the International Classification of Functioning, Disability and Health (ICF) in questionnaires for the upper limb

    Science.gov (United States)

    Philbois, Stella V.; Martins, Jaqueline; Souza, Cesário S.; Sampaio, Rosana F.; Oliveira, Anamaria S.

    2016-01-01

    BACKGROUND: Several Brazilian studies have addressed the International Classification of Functioning, Disability and Health (ICF), but few have analyzed the knowledge of the health professionals with regards to the ICF. OBJECTIVE: To verify whether the classification of the items in the Brazilian-Portuguese versions of The Shoulder Pain and Disability Index (SPADI) and The Disabilities Arm, Shoulder and Hand (DASH) questionnaires, obtained from health professionals who worked with patients having upper limb injuries, could be related to ICF components as defined by others studies. METHOD: There were 4 participants for the group "professionals with high familiarity of the ICF (PHF)" and 19 for the group of "professionals with some or no familiarity of the ICF (PSNF)". The participants judged whether the items on the two questionnaires belonged to the ICF body function, body structure or activity-participation component, and marked a confidence level for each trial using a numerical scale ranging from zero to 10. The items were classified by the discriminant content validity method using the Student'st-test and the Hochberg correction. The ratings were compared to the literature by the percentage of agreement and Kappa coefficient. RESULTS: The percentage of agreement of the rating from the PSNF and the PHF groups with the literature was equal to or greater than 77%. For the DASH, the agreement of the PSNF and PHF groups with the literature were, respectively, moderate (Kappa=0.46 to 0.48) and substantial (Kappa=0.62 to 0.70). CONCLUSIONS: Health professionals were able to correlate the three components of the ICF for most items on the 2 questionnaires, demonstrating some ease of understanding the ICF components. However, the relation of concept of pain with body function component is not clear for professional and deserves a more attentive approach. PMID:26786076

  7. Optimización de láminas reticuladas de una capa

    Directory of Open Access Journals (Sweden)

    Orta, B.

    2008-09-01

    Full Text Available This article presents the reflection on optimum design in one layer lattice shells to cover large span spaces with different base geometries. The objective is to find parameters of form that have more effect on cost, in agreement with the Theory of Design of Structures (3,4, comparable to plane structures (4,12. To reach this aim, a program (8 has been created using Simulated Annealing (SA, a numerical approximation algorithm that finds solutions near optimum. The objective function used is extracted from the Theory of Design of Structures: structural volume. Its definition and characteristics will be seen. Diverse solutions to the numerical proposed examples are shown. These solutions solve similar problems changing the form of the plant to be covered. To finish, parameters of form from found solutions are displayed, and conclusions are extracted, such that SA is an appropriated method for this kind of problems.Este artículo muestra la reflexión sobre el diseño óptimo de laminas reticuladas de una sola capa en la cobertura de espacios de gran luz con diferentes bases. El objetivo es encontrar los parámetros que más efecto tienen en el coste de acuerdo con la Teoría de Diseño de Estructuras (3,4, de manera comparable a estructuras planas (4,12. Para alcanzar este propósito se ha creado un programa (8 que utiliza el Recocido Simulado (SA, una técnica de aproximación numérica que encuentra soluciones cercanas al óptimo. La función objetivo utilizada se extrae de la Teoría de Diseño de Estructuras: volumen estructural, se verán su definición y características. Se muestran diversas soluciones a los ejemplos numéricos propuestos; estas soluciones resuelven problemas similares cambiando la forma de la planta a cubrir. Para terminar se muestran los parámetros de forma obtenidos a partir del análisis de las soluciones, y se extraen conclusiones como que el SA es un método apropiado para esta clase de problemas.

  8. Metodología de evaluación in-situ de capas granulares en pavimentos flexibles, usando el LWD

    OpenAIRE

    Agudelo Castañeda, Adriana Patricia; Burgos Ocación, Iván Darío; González Torres, Edwin Yesid

    2015-01-01

    En la mayoría de los casos para construcción de pavimento, se establecen los resultados de ensayos de densidad como factor aprobatorio de la calidad de las capas construidas, pero estos no se relacionan con los parámetros bajo los cuales se caracterizan las capas en el diseño. Para cambiar esta situación en el control de calidad del pavimento durante su construcción, se elabora esta metodología de evaluación In-situ en capas granulares, la cual se desarrolló a través de una toma de datos de d...

  9. Drive Asymmetry and the Origin of Turbulence in an ICF Implosion

    CERN Document Server

    Thomas, V A; 10.1103/PhysRevLett.109.075004

    2012-01-01

    2D and 3D numerical simulations with the adaptive mesh refinement Eulerian radiation-hydrocode RAGE at unprecedented spatial resolution are used to investigate the connection between drive asymmetry and the generation of turbulence in the DT fuel in a simplified inertial-confinement fusion (ICF) implosion. Long-wavelength deviations from spherical symmetry in the pressure drive lead to the generation of coherent vortical structures in the DT gas and it is the three-dimensional instability of these structures that in turn leads to turbulence and mix. The simulations sug-gest that this mechanism may be an additional important source of mix in ICF implosions. Applications to target ignition at the National Ignition Facility are briefly discussed.

  10. Application of International Classification of Functioning, Disability and Health (ICF in individuals with spinal cord injury

    Directory of Open Access Journals (Sweden)

    Janaina Vall

    2011-06-01

    Full Text Available After spinal cord injury is common functionality is affected. OBJECTIVE: To evaluate the functionality of patients with spinal cord injury. METHOD: Cross-sectional study by means of the International Classification of Functionality (ICF. 109 adults with spinal cord injury in the city of Curitiba, Brazil were evaluated. RESULTS: The categories most compromised in body were intestines and bladder, sexuality, energy, sleep, emotion and weight. In the domain activities and participation, there was greater difficulty in tasks of bathing, toilet and dressing, self care and leisure. In the domain environmental factors, the categories classified as facilitators were: medications, orthoses and wheelchair, attitude of family, transport, social foresight and health services. The categories classified as barriers were: attitude of authorities, social attitudes, education and work. CONCLUSION: The application of the ICF in persons with spinal cord injury demonstrated a series of disabilities and limitations.

  11. Interaction of high power laser beams with plasma in ICF hohlraum using the FDTD method

    Science.gov (United States)

    Lin, Zhili

    2016-11-01

    In the indirect-drive Inertial confinement fusion (ICF) system, groups of laser beams are injected into a gold cylindrical hohlraum and plasma is stimulated with the ablation of the wall of hohlraum by the laser beams. In our work, the finite-difference time-domain (FDTD) method associated with the bilinear transform and Maclaurin series expansion approaches is utilized to examine the laser beam propagation in plasma described by the Drude model. The state-of-the-art approaches for generating the laser beams are presented and realized according to the full utilization of the TF/SF source condition. Base on the previous technologies, the quantitatively numerical analysis of the propagation characteristics of laser beams in the plasma is conducted. The obtained results are illustrated and discussed that are helpful for the parameter optimization of laser beams for an ICF system.

  12. Vesicourethral reflux-induced renal failure in a patient with ICF syndrome due to a novel DNMT3B mutation.

    Science.gov (United States)

    Kutluğ, Seyhan; Ogur, Gönül; Yilmaz, Aysegül; Thijssen, Peter E; Abur, Ummet; Yildiran, Alisan

    2016-12-01

    ICF syndrome is a primary immunodeficiency disease characterized by hypo- or agammaglobulinemia, centromeric instability mainly on chromosomes 1, 9, and 16 and facial anomalies. ICF syndrome presents with frequent respiratory tract infections in infancy. A 20-month-old female patient was referred to our clinic due to frequent lower respiratory tract infections. ICF syndrome was considered because of comorbidity of hypogammaglobulinemia, facial anomalies, and neuromotor growth retardation. Metaphase chromosome analysis revealed centromeric instability on chromosomes 1, 9, and 16 and through Sanger a previously unreported homozygous missense mutation (c.1805T>C; [p.V602A]) was identified in the DNMT3B, confirming ICF1. The patient was found to have a breakdown in renal function 1 year later; the urinary system was examined and bilateral vesicoureteral reflux was found, warranting the need for dialysis in time. This report expands the mutation spectrum of ICF1 and is the first to describe bilateral vesicoureteral reflux accompanying ICF syndrome. © 2016 Wiley Periodicals, Inc.

  13. The ICF as a common language for rehabilitation goal-setting: comparing client and professional priorities

    Directory of Open Access Journals (Sweden)

    van der Merwe Aletia

    2011-10-01

    Full Text Available Abstract Background Joint rehabilitation goals are an important component for effective teamwork in the rehabilitation field. The activities and participation domain of the ICF provides a common language for professionals when setting these goals. Involving clients in the formulation of rehabilitation goals is gaining momentum as part of a person-centred approach to rehabilitation. However, this is particularly difficult when clients have an acquired communication disability. The expressive communication difficulties negatively affect the consensus building process. As a result, obtaining information regarding rehabilitation goals from professionals and their clients warrants further investigation for this particular population. Methods This comparative study investigated clients and their assigned rehabilitation professionals' perception of the importance of ICF activities and participation domains for inclusion in their rehabilitation program. Twelve clients in an acute rehabilitation centre and twenty of their corresponding rehabilitation professionals participated in an activity using the Talking Mats™ visual framework for goal setting. Each participant rated the importance of the nine activities and participation domains of the ICF for inclusion in their current rehabilitation program. Results The ICF domains which consistently appear as very important across these groups are mobility, self-care and communication. Domains which consistently appear in the lower third of the rankings include spare time, learning and thinking and domestic life. Results indicate however that no statistical significant differences exist in terms of the individual domains across each of the participant groups. Within group differences however indicated that amongst the speech-language therapists and physiotherapists there was a statistical significant difference between spare time activities and communication and mobility. Conclusions Findings indicate that

  14. Natriuresis and diuretic hormone synergism in R. prolixus upper Malpighian tubules is inhibited by the anti-diuretic hormone, RhoprCAPA-α2.

    Science.gov (United States)

    Paluzzi, Jean-Paul V; Naikkhwah, Wida; O'Donnell, Michael J

    2012-04-01

    Insects contain an array of hormones that coordinate the actions of the excretory system to achieve osmotic and ionic balance. In the hematophagous insect, Rhodnius prolixus, two diuretic hormones have been identified, serotonin (5HT) and a corticotropin releasing factor-related peptide (RhoprDH), and both lead to an increase in fluid secretion by Malpighian tubules (MTs). However, only 5HT activates reabsorption by the lower MTs to recover K(+) and Cl(-). An anti-diuretic hormone (RhoprCAPA-α2) is believed to coordinate the cessation of the rapid diuresis following blood meal engorgement. However, the role of RhoprCAPA-α2 on fluid secretion by MTs stimulated by RhoprDH was previously unknown. Here we demonstrate that, unlike the inhibitory effect on 5HT-stimulated secretion by MTs, RhoprCAPA-α2 does not inhibit secretion stimulated by RhoprDH although it does abolish the synergism that occurs between the two diuretic hormones. In addition, we show that the natriuresis elicited by either diuretic hormone is reduced by RhoprCAPA-α2. Using electrophysiological tools, we investigate the possible mechanism by which this complex regulatory pathway is achieved. Analysis of the pH of secreted fluid as well as the triphasic response in transepithelial potential in MTs treated with diuretic hormones, suggests that RhoprCAPA-α2 does not inhibit the V-type H(+) ATPase. Taken together, these results indicate that RhoprCAPA-α2 functions to reduce the rapid diuresis following blood feeding, and in addition, it inhibits the natriuresis associated with diuretic hormone stimulated MTs. This may reflect an important regulatory mechanism related to the slow diuresis that occurs as the K(+)-rich blood cells are digested.

  15. Régimen térmico y variabilidad espacial de la capa activa en isla decepcion, Antártica

    Directory of Open Access Journals (Sweden)

    Gabriel Goyanes

    2014-03-01

    Full Text Available El programa de monitoreo de capa activa (CALM fue desarrollado en las últimas décadas con la finalidad de comprender el impacto del cambio climático sobre los ambientes con permafrost. Este trabajo analiza los resultados obtenidos, en los últimos seis años, de los sitios CALM-S Irizar, Cráter Lake y Refugio Chileno, ubicados en Isla Decepción. En ellos se ha medido el espesor, el estado térmico y la distribución espacial de la capa activa. En los sitios Irizar y Refugio Chileno la evolución del espesor de capa activa varió interanualmente sin una clara tendencia dentro del corto período analizado; por el contrario, el sitio Cráter Lake evidenció una tendencia a la disminución de espesor. La distribución espacial como el espesor de dicha capa en los tres sitios de monitoreo, mostraron estar condicionados principalmente por la potencia de la cubierta de nieve, la litología y la exposición a los vientos. El relieve, la topografía de detalle, la orientación de las laderas frente a la radiación solar incidente, ejercieron un control menor sobre esta distribución. El estado térmico de la capa activa evidenció el control ejercido sobre ella de la temperatura del aire y de la cubierta nival. Así bajo reducidos espesores de nieve, el modelo de penetración en profundidad de la isoterma de 0 ºC, ha permitido aproximar satisfactoriamente el espesor de capa activa.

  16. Characterization and rescue of telomeric abnormalities in ICF syndrome type I fibroblasts.

    Directory of Open Access Journals (Sweden)

    Shiran eYehezkel

    2013-02-01

    Full Text Available Mutations in the human DNA methyltransferase 3B (DNMT3B gene lead to ICF (immunodeficiency, centromeric region instability, facial anomalies syndrome type I. We have previously described a telomere-related phenotype in cells from these patients, involving severe hypomethylation of subtelomeric regions, abnormally short telomeres and high levels of telomeric-repeat-containing RNA (TERRA. Here we demonstrate that ICF-patient fibroblasts carry abnormally short telomeres at a low population doubling and enter senescence prematurely. Accordingly, we attempted to rescue the senescence phenotype by ectopic expression of human telomerase, which led to elongated telomeres with hypomethylated subtelomeres. The senescence phenotype was overcome under these conditions, thus dissociating subtelomeric-DNA hypomethylation per se from the senescence phenotype. In addition, we examined whether the subtelomeric methylation could be restored by expression of a normal copy of full length DNMT3B1 in ICF fibroblasts. Ectopic expression of DNMT3B1 failed to rescue the abnormal hypomethylation at subtelomeres. However, partial rescue of subtelomeric-hypomethylation was achieved by co-expression of DNMT3B1 together with DNA methyltransferase 3-like (DNMT3L, encoding a protein that functions as a stimulator of DNMT3A and DNMT3B. DNMT3B1 and DNMT3L are predominantly expressed during early embryonic development, suggesting that de novo subtelomeric DNA methylation during crucial stages of human embryonic development may be necessary for setting and maintaining normal telomere length.

  17. Mapping SAGE questionnaire to the International Classification of Functioning, Disability and Health (ICF).

    Science.gov (United States)

    Raggi, Alberto; Quintas, Rui; Russo, Emanuela; Martinuzzi, Andrea; Costardi, Daniela; Frisoni, Giovanni Battista; Franco, Maria Grazia; Andreotti, Alessandra; Ojala, Matti; Peña, Sebastián; Perales, Jaime; Chatterji, Somnath; Miret, Marta; Tobiasz-Adamczyk, Beata; Koskinen, Seppo; Frattura, Lucilla; Leonardi, Matilde

    2014-01-01

    The collaborative research on ageing in Europe protocol was based on that of the World Health Organization Study on global AGEing and adult health (SAGE) project that investigated the relationship between health and well-being and provided a set of instruments that can be used across countries to monitor health and health-related outcomes of older populations as well as the strategies for addressing issues concerning the ageing process. To evaluate the degree to which SAGE protocol covered the spectrum of disability given the scope of the World Health Organization International Classification of Functioning, Disability and Health (ICF), a mapping exercise was performed with SAGE protocol. Results show that the SAGE protocol covers ICF domains in a non-uniform way, with environmental factors categories being underrepresented, whereas mental, cardiovascular, sensory functions and mobility were overrepresented. To overcome this partial coverage of ICF functioning categories, new assessment instruments have been developed. PRACTITIONER MESSAGE: Mapping exercises are valid procedures to understand the extent to which a survey protocol covers the spectrum of functioning. The mapping exercise with SAGE protocol shows that it provides only a partial representation of body functions and activities and participation domains, and the coverage of environmental factors is poor. New instruments are therefore needed for researchers to properly understand the health and disability of ageing populations.

  18. Estudio de la degradación de la capa de sellado en perfiles de aluminio anodizado

    Directory of Open Access Journals (Sweden)

    Juan G. Castaño

    2010-01-01

    Full Text Available El anodizado del aluminio es simplemente el refuerzo de un proceso natural y espontáneo: la formación de una capa de alúmina estable y protectora mediante la cual se pueden obtener películas con una subcapa exterior porosa que acepta coloración. Luego la operación de sellado permite la formación de una sustancia gelatinosa compuesta principalmente de bohemita, que obstruye los poros y mejora la conservación del aspecto superficial y la resistencia a la corrosión. Utilizando SEM y EDS, en este trabajo se estudiaron las causas de la degradación de la capa de sellado de algunas piezas de aluminio anodizado, independientemente del medio en donde está expuesto el material, y se encontró su origen en la fotodegradación de un aditivo orgánico añadido en exceso durante la operación de sellado.

  19. A proteomic approach for studying insect phylogeny: CAPA peptides of ancient insect taxa (Dictyoptera, Blattoptera as a test case

    Directory of Open Access Journals (Sweden)

    Gäde Gerd

    2009-03-01

    Full Text Available Abstract Background Neuropeptide ligands have to fit exactly into their respective receptors and thus the evolution of the coding regions of their genes is constrained and may be strongly conserved. As such, they may be suitable for the reconstruction of phylogenetic relationships within higher taxa. CAPA peptides of major lineages of cockroaches (Blaberidae, Blattellidae, Blattidae, Polyphagidae, Cryptocercidae and of the termite Mastotermes darwiniensis were chosen to test the above hypothesis. The phylogenetic relationships within various groups of the taxon Dictyoptera (praying mantids, termites and cockroaches are still highly disputed. Results Tandem mass spectrometry of neuropeptides from perisympathetic organs was used to obtain sequence data of CAPA peptides from single specimens; the data were analysed by Maximum Parsimony and Bayesian Interference. The resulting cladograms, taking 61 species into account, show a topology which is in general agreement with recent molecular and morphological phylogenetic analyses, including the recent phylogenetic arrangement placing termites within the cockroaches. When sequence data sets from other neuropeptides, viz. adipokinetic hormones and sulfakinins, were included, the general topology of the cladogram did not change but bootstrap values increased considerably. Conclusion This study represents the first comprehensive survey of neuropeptides of insects for solely phylogenetic purposes and concludes that sequences of short neuropeptides are suitable to complement molecular biological and morphological data for the reconstruction of phylogenetic relationships.

  20. Formación de capas de hierro sobre la pared interna de los reactores de reducción directa. Parte II

    OpenAIRE

    Ortiz, Ubaldo; Aguilar, Juan de (O.S.A.); Viramontes, Ricardo; Berrún, Jorge

    2001-01-01

    En los reactores de reducción directa se presenta el fenómeno de formación de capas del producto llamado “hierro esponja”, las cuales se adhieren al ladrillo sílico-aluminoso. En este segunda parte se analizaron los resultados de las pruebas a nivel laboratorio e industrial y se dedujo un mecanismo que describe al anclaje y crecimiento de las capas. Se confirmó la importancia del esfuerzo cortante y una vez identificado este factor se propuso un método para disminui...

  1. O uso da biópsia aspirativa com agulha fina (BAAF) no diagnóstico de lesão iriana suspeita: relato de caso

    OpenAIRE

    2001-01-01

    Relatar o caso de um paciente que apresentou massa intra-ocular sólida no segmento anterior do olho direito e a investigação diagnóstica escolhida pelos autores. A dúvida diagnóstica e a recusa do paciente em aceitar o tratamento levaram os autores a realizar uma biópsia aspirativa com agulha fina da lesão. A biópsia foi realizada por meio de punção por via corneana, através do humor aquoso até a lesão tumoral. A citologia do material coletado na biópsia determinou a estratégia terapêutica ne...

  2. Las Técnicas Grafo-Plásticas para el desarrollo de la Psicomtricidad Fina en los estudiantes de Educación General Básica

    OpenAIRE

    Tello Báez, Angela del Pilar

    2015-01-01

    1. El Problema. ---2. Marco Teórico. --3. Metodología. --4. Análisis e Interpretación de los Resultados. --5. Propuesta. --6. Conclusiones y Recomendaciones El presente trabajo investigativo se planteó como objetivo elaborar una guía de técnicas grafo-plásticas, en las instituciones Indoamérica,Ing. Alberto EnríquezJarrin y Saquisilí; el propósito es desarrollar la psicomotricidad fina en los niños. Es importante poner en práctica la metodología investigación acción, esto nos sirve para or...

  3. Bacteraemia with Campylobacter jejuni: no association with the virulence genes iam, cdtB, capA or virB.

    Science.gov (United States)

    Nielsen, H; Persson, S; Olsen, K E P; Ejlertsen, T; Kristensen, B; Schønheyder, H C

    2010-03-01

    The role of bacterial genes in the determination of the clinical spectrum of Campylobacter jejuni infection is unclear. We compared clinical isolates from invasive blood-stream infection with stool isolates from gastroenteritis and found no association of the putative virulence genes iam, capA, virB and cdtB with clinical presentation.

  4. Estudio teórico de la distribución catiónica en la capa octaédrica de silicatos laminares

    Science.gov (United States)

    Hernández-Laguna, A.

    Los silicatos laminares son unos minerales de gran extensión en la corteza de nuestro y otros planetas, y se ha detectado su presencia en masas de partículas de polvo interplanatario. Están formados por láminas estructuradas en una capa tetraedros de sílice y una de octaédros de oxihidroxido de aluminio. Según el número de capas y la disposición aparecen distintos minerales. Además, también pueden aparecer distintos minerales como consecuencia de la substitución isomórfica de cationes en la capas, en particular, Al(III) por Si en la capa tetraédrica y Fe(III) y/o Mg(II) por Al(III) en la octaédrica. Cuando el catión substituyente presenta un estado de oxidación más bajo que al que substituye genera carga negativa que tiene que neutralizarse con cationes que se disponen en el espacio interlaminar. En este trabajo vamos a estudiar, mediante distintos métodos computacionales, las distribuciones de dichos cationes de substitución en la capa octaédrica de silicatos laminares 2:1 (dos capas tetraédricas y en medio una octaédrica), en particular, en los minerales esmectitas e ilitas. En primer lugar, estudiaremos la distribución de dichos cationes en la capa octaédrica en un modelo de gas reticular por el método de Monte Carlo, minimizando el número de pares de cationes Al, Fe y Mg de nuestro modelo con respecto a los procedentes de resultados espectroscópicos de muestras de minerales. Posteriormente, y mediante un modelo de potenciales empíricos, estudiamos la energética de las distribuciones binarias en dichos minerales, generando unos potenciales de interacción intercambio a dos y tres cationes (extrapolables a cualquier filosilicato) que son la base para una investigación Monte Carlo-"simulated-annealing" en la que se encuentran las transiciones de fase y las estructuras ordenadas, dependiendo dichas estructuras y la temperatura de cambio de fase de la de la naturaleza y concentración de los cationes de substitución. También se han

  5. The International Classification of Functioning, Disability and Health (ICF): a unifying model for the conceptual description of the rehabilitation strategy.

    Science.gov (United States)

    Stucki, Gerold; Cieza, Alarcos; Melvin, John

    2007-05-01

    An important basis for the successful development of rehabilitation practice and research is a conceptually sound description of rehabilitation understood as a health strategy based on a universally accepted conceptual model and taxonomy of human functioning. With the approval of the International Classification of Functioning, Disability and Health (ICF) by the World Health Assembly in 2001 and the reference to the ICF in the World Health Assembly's resolution on "Disability, including prevention, management and rehabilitation" in 2005, we can now rely on a universally accepted conceptual model. It is thus time to initiate the process of evolving an ICF-based conceptual description that can serve as a basis for similar conceptual descriptions and according definitions of the professions applying the rehabilitation strategy and of distinct scientific fields of human functioning and rehabilitation research. In co-operation with the Physical and Rehabilitation Medicine (PRM) section of the European Union of Medical Specialists (UEMS) and its professional practice committee, we present a first tentative version of an ICF-based conceptual description in this paper. A brief definition describes rehabilitation as the health strategy applied by PRM and professionals in the health sector and across other sectors that aims to enable people with health conditions experiencing or likely to experience disability to achieve and maintain optimal functioning in interaction with the environment. Readers of the Journal of Rehabilitation Medicine are invited to contribute towards achieving an internationally accepted ICF-based conceptual description of rehabilitation by submitting commentaries to the Editor of this journal.

  6. International Classification of Functioning, Disability and Health (ICF) Core Set for patients with vertigo, dizziness and balance disorders.

    Science.gov (United States)

    Grill, Eva; Bronstein, Adolfo; Furman, Joseph; Zee, David S; Müller, Martin

    2012-01-01

    Vertigo, dizziness and balance disorders have major impact on independence, employability, activities and participation. There are many measures for the assessment of the impact of vertigo, but no consensus exists on which aspects should be measured. The objective of this study was to develop international standards (ICF Core Sets) for patients with vertigo and dizziness to describe functioning. The development of the ICF Core Sets involved a formal decision-making and consensus process, integrating evidence from preparatory studies including qualitative interviews with patients, a systematic review of the literature, a survey with health professionals, and empirical data collection from patients. Twenty-seven experts selected 100 second level categories for the comprehensive Core Set and 29 second level categories for the Brief Core Set. The largest number of categories was selected from the ICF component Activities and Participation (40). Twenty-five categories were selected from the component Body Functions, six from Body Structures, and 29 from Environmental Factors. The ICF Core Set for vertigo is designed for physicians, nurses, therapists and other health professionals working in inpatient or ambulatory settings. ICF Core Sets create patient-relevant outcomes that can be used as evidence for the success of treatments.

  7. Damage behavior of Nd:glass of high-power disk amplifier medium in ICF Facility

    Science.gov (United States)

    He, Shaobo; Chen, Lin; Yuan, Xiaodong; Chen, Yuanbin; Cheng, Xiaofeng; Xie, Xudong; Wang, Wenyi; Zu, Xiaotao

    2016-12-01

    Large aperture Nd:glass disk is often used as the amplifier medium in the inertial confinement fusion (ICF) facilities. The typical size of Nd:glass is up to 810mm×460mm×40mm and more than 3,000 Nd:glass components are needed in the ICF facility. At present, the 3ω fused silica glass and DKDP crystal are mainly responsible for the damage of driver used for ICF. However, with the enlargement of the facility and increase of laser shot number, the laser damage of Nd:glass at 1ω waveband is still an important problem to limit the stable operation of facility and improvement of laser beam quality. In this work, the influence of Nd:glass material itself, mechanical processing, service environment, and laser beam quality on its damage behavior is investigated experimentally and theoretically. The results and conclusions can be summarized as follows: (1) It is very important to control the concentration of platinum impurity particles during melting and the sputtering effect of the cladding materials. (2) The number and length of fractural and brittle scratches should be strictly suppressed during mechanical processing of Nd:glass. (3) The B-integral of high power laser beam should be rigorously controlled. Particularly, the top shape of pulses must be well controlled when operating at high peak laser power. (4) The service environment should be well managed to make sure the cleanness of the surface of Nd:glass better than 100/A level during mounting and running. (5) The service environment and beam quality should be monitored during operation.

  8. Possibilities and Implications of Using the ICF and Other Vocabulary Standards in Electronic Health Records.

    Science.gov (United States)

    Vreeman, Daniel J; Richoz, Christophe

    2015-12-01

    There is now widespread recognition of the powerful potential of electronic health record (EHR) systems to improve the health-care delivery system. The benefits of EHRs grow even larger when the health data within their purview are seamlessly shared, aggregated and processed across different providers, settings and institutions. Yet, the plethora of idiosyncratic conventions for identifying the same clinical content in different information systems is a fundamental barrier to fully leveraging the potential of EHRs. Only by adopting vocabulary standards that provide the lingua franca across these local dialects can computers efficiently move, aggregate and use health data for decision support, outcomes management, quality reporting, research and many other purposes. In this regard, the International Classification of Functioning, Disability, and Health (ICF) is an important standard for physiotherapists because it provides a framework and standard language for describing health and health-related states. However, physiotherapists and other health-care professionals capture a wide range of data such as patient histories, clinical findings, tests and measurements, procedures, and so on, for which other vocabulary standards such as Logical Observation Identifiers Names and Codes and Systematized Nomenclature Of Medicine Clinical Terms are crucial for interoperable communication between different electronic systems. In this paper, we describe how the ICF and other internationally accepted vocabulary standards could advance physiotherapy practise and research by enabling data sharing and reuse by EHRs. We highlight how these different vocabulary standards fit together within a comprehensive record system, and how EHRs can make use of them, with a particular focus on enhancing decision-making. By incorporating the ICF and other internationally accepted vocabulary standards into our clinical information systems, physiotherapists will be able to leverage the potent

  9. Studying of Laser Plasma Physics Related With Fast Ignition of ICF

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Fast ignition(FI) concept of ICF is one of the most attractive application of high intensity ultrashort laser. The UV light has some advantages for applying to fast ignition, the first, as the I λ2 scaling law of hot electron temperature, at the FI required intensity(1020 W/cm2), the long wavelength light will generate >10 MeV electron that can not deposit energy efficiently in the fuel region. Meanwhile the UV light can just generate the electron with the required energy of 1 MeV.

  10. Improvements in ICF target fabrication through high precision assembly and nondestructive characterization

    Energy Technology Data Exchange (ETDEWEB)

    Obrey, Kimberly Ann Defriend [Los Alamos National Laboratory; Schmidt, Derek W [Los Alamos National Laboratory; Patterson, Brian M [Los Alamos National Laboratory; Day, Robert D [Los Alamos National Laboratory; Valdez, Adelaida C [Los Alamos National Laboratory; Capelli, Deanna [Los Alamos National Laboratory; Perea, Ron [Los Alamos National Laboratory; Randolph, Blaine [Los Alamos National Laboratory; Hatch, Doug [Los Alamos National Laboratory; Garcia, Felix [Los Alamos National Laboratory; Honnell, Diana [Los Alamos National Laboratory

    2009-01-01

    Current ICF and HED targets are fielded on Omega, Z, and Trident, and future campaigns will be fielded on NIF. NIF will only field less than 2 shots per day. With such few experiments, target fabrication and target alignment accuracy, enhanced metrology and advanced component machining will be even more important. Future target designs are also becoming more complex and more stringent in terms of accuracy. Several steps have been taken to improve the fabrication and characterization of targets, such as instituting an automated assembly station with 3 mm tolerances, utilizing nondestructive characterization tools for rapid component metrology and target assembly, and advancing machining capabilities. Recapitalization of target fabrication infrastructure is continuous.

  11. Sensitivity of ICF ignition conditions to non-Maxwellian DT fusion reactivity

    Directory of Open Access Journals (Sweden)

    Garbett W.J.

    2013-11-01

    Full Text Available The hotspot ignition conditions in ICF are determined by considering the power balance between fusion energy deposition and energy loss terms. Uncertainty in any of these terms has potential to modify the ignition conditions, changing the optimum ignition capsule design. This paper considers the impact of changes to the DT fusion reaction rate due to non-thermal ion energy distributions. The DT fusion reactivity has been evaluated for a class of non-Maxwellian distributions representing a perturbation to the tail of a thermal distribution. The resulting reactivity has been used to determine hotspot ignition conditions as a function of the characteristic parameter of the modified distribution.

  12. Burning the DT-plasma with inert impurities and non-cryogenic ICF-target with solid fuel

    Directory of Open Access Journals (Sweden)

    Gus'kov S.Yu.

    2013-11-01

    Full Text Available The ignition criterion, ignition energy and gain of DT-plasma of ICF-target in the presence of impurities of light atoms such as beryllium, carbon and lithium at their arbitrary concentration are found. It is shown that the most promising type of non-cryogenic solid thermonuclear fuel is DT-hydride of beryllium (BeDT. It is suggested to apply the targets with such a fuel as: (1 Fast-ignited ICF-target at the ignition energy of 25–50 kJ and compression driver energy of 2–3 MJ; (2 ICF-target spark-ignited by 15–20 MJ heavy ion driver; (3 Spark-ignited target by 5–7 MJ laser as a neutron source for hybrid fusion-fission.

  13. The Role of the WHO ICF as a Framework to Interpret Barriers and to Inclusion: Visually Impaired People's Views and Experiences of Personal Computers

    Science.gov (United States)

    Douglas, Graeme; Corcoran, Christine; Pavey, Sue

    2007-01-01

    This article describes how the World Health Organisation's International Classification of Functioning, Disability, and Health (ICF), 2001, was used as a framework for the design of the interview schedule used in the Network 1000 project. It is argued that the ICF offers a vocabulary to enable visually impaired participants to describe their lives…

  14. ICF quarterly report October-December 1998 volume 8, number 1

    Energy Technology Data Exchange (ETDEWEB)

    Feit, M

    1998-09-08

    This issue of the ICF Quarterly Report focuses on the final section of the 192-arm, 1.8-MJ National Ignition Facility (NIF). We describe both technological advances necessary for optimal utilization of the delivered energy and the hohlraum physics resulting from extremely high energy densities. Two articles belong to the first category. The conversion of infrared light to ultraviolet occurs at the tripler in the NIF's Final Optics Assembly. It is then necessary to separate any unconverted (first- and second-harmonic) light from the tripled-frequency light passed to the target. Large-Aperture Color-Separation Gratings for Diverting Unconverted Light Away from the NIF Target describes the design and fabrication of novel diffraction gratings that fulfill this function. In both direct- and indirect-drive ICF, the symmetry of the capsule as it compresses is crucial. The NIF will have 48 clusters of four beams incident on targets. Optimization of Beam Angles for the National Ignition Facility (p. 15) presents the rationale used to assign beam angles for cylindrical indirect drive while still allowing direct-drive and tetrahedral indirect-drive experiments to be performed.

  15. Progress in laboratory high gain ICF (inertial confinement fusion): Prospects for the future

    Energy Technology Data Exchange (ETDEWEB)

    Storm, E.; Lindl, J.D.; Campbell, E.M.; Bernat, T.P.; Coleman, L.W.; Emmett, J.L.; Hogan, W.J.; Hunt, J.T.; Krupke, W.F.; Lowdermilk, W.H.

    1988-01-01

    Inertial confinement fusion (ICF), a thermonuclear reaction in a small (/approximately/5 mm diameter) fuel capsule filled with a few milligrams of deuterium and tritium, has been the subject of very fruitful experimentation since the early 1970's. High gain ICF is now on the threshold of practical applications. With a Laboratory Microfusion Facility (LMF), these applications will have major implications for national defense, basic and applied science, and power production. With a driver capable of delivering about 10 MJ in a 10-ns pulse at an intensity of /approximately/3 /times/ 10/sup 14/ W/cm/sup 2/, an appropriately configured cryogenic capsule could be compressed to a density of about 200 g/cm/sup 3/ and a temperature of 3--5 keV. Under these conditions, up to 10 mg of DT could be ignited, and with a burn efficiency of about 30%, release up to 1000 MJ of fusion energy, an energy gain of about 100. A thousand megajoules is equivalent to about one quarter ton of TNT, or about 7 gallons of oil--an amount of energy tractable under laboratory conditions and potentially very useful for a variety of applications. 61 refs., 33 figs.

  16. L’ICF-CY per la progettazione inclusiva per gli alunni con DSA

    Directory of Open Access Journals (Sweden)

    Marina Chiaro

    2013-09-01

    Full Text Available Il lavoro presenta i principali risultati di una ricerca a carattere teorico-esplorativo, finalizzata a valutare quanto lo strumento dell’International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY sia conosciuto ed utilizzato nei diversi contesti educativi per l’osservazione degli allievi e del loro “funzionamento” in senso dinamico-evolutivo, in interazione con i fattori ambientali, e finalizzato ad una progettazione educativo-didattica significativamente orientata alla prospettiva inclusiva. A tal fine sono stati intervistati gli insegnanti delle scuole di ogni ordine e grado del Lazio iscritti al Master in Didattica e Psicopedagogia per gli alunni con Disturbi Specifici di Apprendimento (DSA presso l’Università degli Studi di Roma Tre. La scelta è coerente con la direttiva MIUR del 2012 dove viene considerato rilevante ai fini della individuazione dei Bisogni Educativi Speciali dell’alunno, ed in particolare degli allievi con DSA, l’apporto, anche sul piano culturale del modello diagnostico ICF-CY che considera la persona nella sua totalità, in una prospettiva bio-psico-sociale.

  17. A direct method for determining the mass of gases in ICF shell

    Institute of Scientific and Technical Information of China (English)

    杨传路; 朱正和; 汪蓉; 谭明亮; 蒋刚; 王明达; 郑永铭; 唐永建; 郑志坚; 赵永宽

    2002-01-01

    In the present paper, the defects of dew point method for measuring the mass of gas filled in ICF shells are analyzed. An accurate state equation for gas D2 is deduced from Benedict-Webb-Rubin (BWR) equation and experimental data in planar phase. A direct method to determine gas mass in ICF shells via measuring the temperature and pressure outside the shells and solving the equation of state by numerical method is proposed. It overcomes the theoretical defects of dew point method and the complexities of equipment. In the present method, the state equation can be improved by more accurately measuring P-V-T values of gas D2, so the measuring precision of the mass of gas in the shells can also be improved. The present method is effective for treating mix gases filled in the shells as well. The errors between the computational results and experimental data are very small. Some cases in the filling process are predicted, and the proper temperature and pressure for filling gases effectively are also suggested.

  18. Multidisciplinary assessment of children with developmental coordination disorder: using the ICF framework to inform assessment.

    Science.gov (United States)

    Watter, Pauline; Rodger, Sylvia; Marinac, Julie; Woodyatt, Gail; Ziviani, Jenny; Ozanne, Anne

    2008-01-01

    The aim of this study was to describe relationships in young children with motor coordination problems between measures of motor, functional, self-efficacy, and communication administered by a multidisciplinary team and the fit of these measures within the framework of the International Classification of Functioning, Disability and Health (ICF) (World Health Organisation, 2001). Sixty children, 40 males and 20 females, with mean age 72.5 months (SD= 11.4 months) referred to a university physiotherapy clinic met the inclusion criteria for developmental coordination disorder (DCD). Each measure provided a different perspective of performance when considered within the framework of the ICF. The findings suggest caution when using the Movement Assessment Battery for Children (M-ABC) for the purpose of diagnosis with young referred children, since 25 of the 60 children scored > 15th percentile, despite demonstrating motor deficits at home and school. Further research is needed to address assessment at the participation level. Viewing children from the multiple perspective of each discipline highlights the range of challenges faced by children with DCD.

  19. Fine litter accumulation in Central Amazonian Tropical Rainforest canopy Acúmulo de liteira fina no dossel de uma Floresta Tropical na Amazônia Central

    Directory of Open Access Journals (Sweden)

    Fabiana Rita do Couto-Santos

    2010-12-01

    Full Text Available Fine litter dynamics within the canopy differ from litter dynamics on the forest floor for reasons such as differences in microclimate, substrate, disturbance level, stratum influence and decomposition rates. This study is the first attempt to quantify the fine litter accumulated in the canopy of Central Amazonian forests. We compared the canopy litter accumulation to fine litter-layer on forest floor and to other forests and also investigated which were the mostly accumulated litter omponents. We found that Central Amazonian Rainforest intercepts greater fine litter in the canopy (294 g.m-2 compared to other forest formations with higher winds speed as in a Costa Rican Cloud Forest (170 g.m-2. The mean canopy fine litter accumulated at the end of the dry season was less than a half of that on soil surface (833 g.m-2 and the fine wood component dominates the canopy samplings (174 g.m-2 while leafy component predominate on soil surface litter (353 g.m-2.A dinâmica da liteira fina no dossel difere da dinâmica no chão da floresta por razões como diferenças no microclima, tipo de substrato, taxas de decomposição, distúrbios e influência dos estratos. Esta é a primeira tentativa de quantificar a liteira fina acumulada no dossel das florestas da Amazônia Central. Comparamos o acúmulo da liteira no dossel com a camada de liteira do chão da floresta e com outros tipos de florestas e investigamos quais componentes da liteira acumularam em maiores quantidades. A floresta estudada na Amazônia Central interceptou uma maior quantidade de liteira no dossel (294 g.m-2 do que outras florestas com maior influência dos ventos, como na Costa Rica (170 g.m-2. A média de liteira no dossel no fim da estação seca foi menos da metade da acumulada sobre o solo (833 g.m-2. Os galhos finos dominaram nas amostras do dossel (174 g.m-2 enquanto as folhas predominaram na liteira sobre o solo (353 g.m-2.

  20. Respuesta metalúrgica de fracciones finas de minerales sulfurados de cobre en un proceso combinado de flotación modificada y biolixiviación agitada

    Directory of Open Access Journals (Sweden)

    Ibáñez, J. P.

    2007-04-01

    Full Text Available The metallurgical behavior of fine fractions of copper sulfide minerals of Compañía Minera Quebrada Blanca S.A. was studied by concentration through flotation in aqueous media modified by alcohol followed by bioleaching of the concentrates. By using a 1 % v/v of methanol, the metallurgical recovery of copper reaches 88 %, while the iron recovery was 43 %, the weight recovery was 18%, which indicates a high selectivity. These concentrates were then bioleached with and without nutrient medium, reaching 80 % of copper recovery after 10 and 17 days, respectively. Then, it is possible to conclude that this concentration-bioleaching metallurgical process is a promising route for copper recovery from the fine fraction of sulfide minerals.

    Se estudió la respuesta metalúrgica de la fracción fina, 100 % -100 # ASTM, de un mineral sulfurado de cobre de la Compañía Minera Quebrada Blanca S.A., sometido a una etapa de concentración mediante flotación en medio acuoso modificado (FEMAM® con metanol y la posterior biolixiviación agitada de este concentrado. Al emplear un 1 % v/v de metanol se logran los mejores resultados: una recuperación metalúrgica de cobre y hierro de 88 y 43 %, respectivamente, y una recuperación en peso del 18 %. Lo cual indica una alta selectividad de este tipo de flotación para especies sulfuradas de cobre. El concentrado FEMAM® fue posteriormente sometido a una etapa de biolixiviación agitada en ausencia y presencia del medio nutriente 9 K, lográndose el 80 % de extracción de cobre a los 17 y 10 días, respectivamente. Esto permite concluir que una ruta de concentración-biolixiviación es una alternativa tecnológica apropiada para procesar la fracción fina de minerales sulfurados de cobre.

  1. Masa total y contenido de nutrientes en raíces finas de ecosistemas forestales (pinus patula schltdl y cham cupressus lusitanica mill y quercus humboldtii bonpl.) de piedras blancas, antioquia-colombia.

    OpenAIRE

    2011-01-01

    En la región de Piedras Blancas, Antioquia - Colombia, se realizó un muestreo de raíces finas (5 mm) en tres parcelas permanentes establecidas en bosques de pino pátula (Pinus patula Schltdl y Cham), ciprés (Cupressus lusitanica Mill) y roble (Quercus humboldtii Bonpl.) a diferentes profundidades: 0-30, 30-50 y 50-80 cm, con el fin de determinar la masa de raíces, y la concentración y contenido de nutrientes en cada cobertura vegetal. La masa de raíces finas disminuyó rápidamente a medida q...

  2. Estimativa da biomassa e do comprimento de raízes finas em Eucalyptus urophylla S.T. Blake no município de Santa Maria-RS

    Directory of Open Access Journals (Sweden)

    Witschoreck Rudi

    2003-01-01

    Full Text Available O objetivo do presente trabalho foi estimar a biomassa e o comprimento de raízes finas (< 2 mm de diâmetro, em diferentes profundidades do solo, para a espécieEucalyptus urophylla S.T. Blake, com 10 anos de idade. O estudo foi realizado no município de Santa Maria-RS, no campus da Universidade Federal de Santa Maria. O talhão plantado com eucalipto tem 27 m de comprimento por 14 m de largura, em espaçamento 3 x 2 m. Foram amostrados quatro monolitos de 25 x 25 x 60 cm. Os monolitos foram divididos em seis perfis geométricos, nas profundidades de 0-10, 10-20, 20-30, 30-40, 40-50, 50-60 cm. A separação das raízes do solo foi por meio de um conjunto de duas peneiras (2 e 1 mm de malha e jatos d'água. Na determinação do comprimento de raízes foi utilizado o método de intersecção, produzindo fotos com o uso de scanner. Os resultados revelaram alta concentração das raízes finas nos primeiros 20 cm de solo. A biomassa total de raízes finas encontradas para o Eucalyptus urophylla foi de 1.451,6 kg/ha, devendo ser ressaltado que 57,9% estavam concentradas nos primeiros 20 cm de solo. Constatou-se que o comprimento total de raízes finas foi de 27.968,9 km/ha e que 64,3% destes estavam nos primeiros 20 cm de profundidade.

  3. Se necesita mayor sintonía fina entre la política fiscal y la competitividad de la economía

    Directory of Open Access Journals (Sweden)

    Marcelo Capello

    2015-06-01

    Full Text Available Hacia el final de la Convertibilidad la economía argentina se hallaba en un callejón sin salida, principalmente por dos problemas: i Baja competitividad en la producción de bienes; y ii Inviabilidad fiscal. Si bien la competitividad de una economía no está dada sólo por el nivel del tipo de cambio real, evidentemente que el hecho de que Argentina se mantuviera once años con cambio fijo contra el dólar, mientras muchos países del mundo devaluaron en ese lapso contra dicha moneda, deterioró las posibilidades locales de competir en una economía abierta. En el presente trabajo se analiza la evolución del comportamiento de las principales variables macroeconómicas y fiscales en los últimos años. Se concluye que  será cada vez más importante mantener una sintonía muy fina para lograr un conveniente equilibrio entre la evolución del gasto público, la presión tributaria legal y la competitividad de los sectores productivos.Palabras Clave: Política Fiscal, Análisis Macroeconómico, Argentina

  4. Impactos socioambientais e de segurança do alimento na gestão da produção integrada de uvas finas de mesa

    Directory of Open Access Journals (Sweden)

    Francisco Alves Pinheiro

    2009-05-01

    Full Text Available Este artigo procurou identificar e analisar os impactos socioambientais e de Segurança do
    Alimento do processo de certificação da produção de uvas finas de mesa no programa de
    Produção Integrada de Uva (PI-UVA recentemente implantado na região do Submédio do
    Vale do rio São Francisco, no município de Petrolina. A metodologia adotada baseou-se em
    um estudo de caso, analisando-se o processo de certificação vivenciado por uma média
    empresa da região. Os resultados obtidos apontam que a certificação não é só
    compensadora em termos de abertura e manutenção de importantes fatias do mercado
    externo, mas, mesmo internamente apresenta vantagens ao nível do controle operacional e
    satisfação no trabalho entre seus funcionários

  5. ICF syndrome mutations cause a broad spectrum of biochemical defects in DNMT3B-mediated de novo DNA methylation.

    Science.gov (United States)

    Moarefi, Amir H; Chédin, Frédéric

    2011-06-24

    The DNMT3B de novo DNA methyltransferase (DNMT) plays a major role in establishing DNA methylation patterns in early mammalian development, but its catalytic mechanism remains poorly characterized. Here, we provide a comprehensive biochemical analysis of human DNMT3B function through the characterization of a series of site-directed DNMT3B variants associated with immunodeficiency, centromere instability, and facial anomalies (ICF) syndrome. Our data reveal several novel and important aspects of DNMT3B function. First, DNMT3B, unlike DNMT3A, requires a DNA cofactor in order to stably bind to S-adenosyl-l-methionine (SAM), suggesting that it proceeds according to an ordered catalytic scheme. Second, ICF mutations cause a broad spectrum of biochemical defects in DNMT3B function, including defects in homo-oligomerization, SAM binding, SAM utilization, and DNA binding. Third, all tested ICF mutations, including the A766P and R840Q variants, result in altered catalytic properties without interfering with DNMT3L-mediated stimulation; this indicates that DNMT3L is not involved in the pathogenesis of ICF syndrome. Finally, our study reveals a novel level of coupling between substrate binding, oligomerization, and catalysis that is likely conserved within the DNMT3 family of enzymes.

  6. Utility of the International Classification of Functioning, Disability and Health (ICF) for Educational Psychologists' Work

    Science.gov (United States)

    Aljunied, Mariam; Frederickson, Norah

    2014-01-01

    Despite embracing a bio-psycho-social perspective, the World Health Organization's International Classification of Functioning, Disability and Health (ICF) assessment framework has had limited application to date with children who have special educational needs (SEN). This study examines its utility for educational psychologists' work…

  7. The Development of an ICF-Oriented, Adaptive Physician Assessment Instrument of Mobility, Self-care, and Domestic Life

    Science.gov (United States)

    Farin, Erik; Fleitz, Annette

    2009-01-01

    The objective of this study was development and psychometric testing of an adaptive, International Classification of Functioning, Disability, and Health (ICF)-oriented questionnaire to be processed by the rehabilitation physician that aids in assessing mobility, self-care, and domestic life (Moses-Physician). The intent is to develop a physician…

  8. Low Back Pain in 17 Countries, a Rasch Analysis of the ICF Core Set for Low Back Pain

    Science.gov (United States)

    Roe, Cecilie; Bautz-Holter, Erik; Cieza, Alarcos

    2013-01-01

    Previous studies indicate that a worldwide measurement tool may be developed based on the International Classification of Functioning Disability and Health (ICF) Core Sets for chronic conditions. The aim of the present study was to explore the possibility of constructing a cross-cultural measurement of functioning for patients with low back pain…

  9. The Importance of Motor Functional Levels from the Activity Limitation Perspective of ICF in Children with Cerebral Palsy

    Science.gov (United States)

    Mutlu, Akmer

    2010-01-01

    Our purpose in this study was to evaluate performance and capacity as defined by Gross Motor Function Classification System (GMFCS) and Manual Ability Classification System (MACS) from the "activity limitation" perspective of International Classification of Functioning, Disability, and Health (ICF) and to investigate the relationship between the…

  10. DEVELOPMENT AND TESTING PSYCHOMETRIC PROPERTIES OF AN ICF-BASED HEALTH MEASURE : THE NEUROMUSCULAR DISEASE IMPACT PROFILE

    NARCIS (Netherlands)

    Bos, Isaac; Kuks, Jan B. M.; Wynia, Klaske

    2015-01-01

    Objectives: To develop a measure that is based on the International Classification of Functioning, Disability and Health (ICF) and reflects the prevalence and severity of disabilities related to neuromuscular disorders, and to evaluate the psychometric properties of this measure. Methods: A prelimin

  11. Integration and application of the International Classification of Functioning, Disability and Health (ICF) in return to work

    NARCIS (Netherlands)

    Escorpizo, Reuben; Finger, Monika E; Reneman, Michiel F; Schultz, Izabela Z.; Gatchel, Robert J.

    2016-01-01

    The experience of work and employment is universal; hence any form of disability that may affect work (i.e., work disability) becomes crucial. In this chapter, the International Classification of Functioning, Disability and Health (ICF) model of the World Health Organization (WHO) will be discussed,

  12. Content Validity of the Comprehensive ICF Core Set for Multiple Sclerosis from the Perspective of Speech and Language Therapists

    Science.gov (United States)

    Renom, Marta; Conrad, Andrea; Bascuñana, Helena; Cieza, Alarcos; Galán, Ingrid; Kesselring, Jürg; Coenen, Michaela

    2014-01-01

    Background: The Comprehensive International Classification of Functioning, Disability and Health (ICF) Core Set for Multiple Sclerosis (MS) is a comprehensive framework to structure the information obtained in multidisciplinary clinical settings according to the biopsychosocial perspective of the International Classification of Functioning,…

  13. Digital Versatile Rewritable Disc (DVD-RAM) Complementary Allocated Pit Address (CAPA) Signal and Tracking Error Signal Detection Method; Improving Objective Lens Radial Shift Immunity

    Science.gov (United States)

    Yoshizawa, Takashi; Satoh, Hiroharu; Ohsawa, Hideki

    1998-04-01

    The complementary allocated pit address (CAPA) signal in a digital versatile rewritable disc (DVD-RAM) is susceptible to an objective lens radial shift; the reduction of its signal amplitude occurs and the S/N ratio decreases. To alleviate this situation, we propose a new readout signal processing scheme, the center separate detection method (CSD) of discarding a large amount of the 0-th diffracted light beam from the disc. We confirmed the expected results by numerical simulation.

  14. Theranostic Approach for Metastatic Pigmented Melanoma Using ICF15002, a Multimodal Radiotracer for Both PET Imaging and Targeted Radionuclide Therapy

    Directory of Open Access Journals (Sweden)

    Latifa Rbah-Vidal

    2017-01-01

    Full Text Available PURPOSE: This work reports, in melanoma models, the theranostic potential of ICF15002 as a single fluorinated and iodinated melanin-targeting compound. METHODS: Studies were conducted in the murine syngeneic B16BL6 model and in the A375 and SK-MEL-3 human xenografts. ICF15002 was radiolabeled with fluorine-18 for positron emission tomography (PET imaging and biodistribution, with iodine-125 for metabolism study, and iodine-131 for targeted radionuclide therapy (TRT. TRT efficacy was assessed by tumor volume measurement, with mechanistics and dosimetry parameters being determined in the B16BL6 model. Intracellular localization of ICF15002 was characterized by secondary ion mass spectrometry (SIMS. RESULTS: PET imaging with [18F]ICF15002 evidenced tumoral uptake of 14.33 ± 2.11%ID/g and 4.87 ± 0.93%ID/g in pigmented B16BL6 and SK-MEL-3 models, respectively, at 1 hour post inoculation. No accumulation was observed in the unpigmented A375 melanoma. SIMS demonstrated colocalization of ICF15002 signal with melanin polymers in melanosomes of the B16BL6 tumors. TRT with two doses of 20 MBq [131I]ICF15002 delivered an absorbed dose of 102.3 Gy to B16BL6 tumors, leading to a significant tumor growth inhibition [doubling time (DT of 2.9 ± 0.5 days in treated vs 1.8 ± 0.3 in controls] and a prolonged median survival (27 days vs 21 in controls. P53S15 phosphorylation and P21 induction were associated with a G2/M blockage, suggesting mitotic catastrophe. In the human SK-MEL-3 model, three doses of 25 MBq led also to a DT increase (26.5 ± 7.8 days vs 11.0 ± 3.8 in controls and improved median survival (111 days vs 74 in controls. CONCLUSION: Results demonstrate that ICF15002 fulfills suitable properties for bimodal imaging/TRT management of patients with pigmented melanoma.

  15. Reliability, construct validity and measurement potential of the ICF comprehensive core set for osteoarthritis

    Directory of Open Access Journals (Sweden)

    Kurtaiş Yeşim

    2011-11-01

    Full Text Available Abstract Background This study aimed to investigate the reliability and construct validity of the International Classification of Functioning, Disability and Health (ICF Comprehensive Core Set for osteoarthritis (OA in order to test its possible use as a measuring tool for functioning. Methods 100 patients with OA (84 F, 16 M; mean age 63 yr completed forms including demographic and clinical information besides the Short Form (36 Health Survey (SF-36® and the Western Ontario and McMaster Universities Index of Osteoarthritis (WOMAC. The ICF Comprehensive Core Set for OA was filled by health professionals. The internal construct validities of "Body Functions-Body structures" (BF-BS, "Activity" (A, "Participation" (P and "Environmental Factors" (EF domains were tested by Rasch analysis and reliability by internal consistency and person separation index (PSI. External construct validity was evaluated by correlating the Rasch transformed scores with SF-36 and WOMAC. Results In each scale, some items showing disordered thresholds were rescored, testlets were created to overcome the problem of local dependency and items that did not fit to the Rasch model were deleted. The internal construct validity of the four scales (BF-BS 16 items, A 8 items, P 7 items, EF 13 items were good [mean item fit (SD 0.138 (0.921, 0.216 (1.237, 0.759 (0.986 and -0.079 (2.200; person item fit (SD -0.147 (0.652, -0.241 (0.894, -0.310 (1.187 and -0.491 (1.173 respectively], indicating a single underlying construct for each scale. The scales were free of differential item functioning (DIF for age, gender, years of education and duration of disease. Reliabilities of the BF-BS, A, P, and EF scales were good with Cronbach's alphas of 0.79, 0.86, 0.88, and 0.83 and PSI's of 0.76, 0.86, 0.87, and 0.71, respectively. Rasch scores of BF-BS, A, and P showed moderate correlations with SF-36 and WOMAC scores where the EF had significant but weak correlations only with SF36-Social

  16. Recent Measurements of DT Gamma to Neutron Branching Ratio at ICF Conditions

    Science.gov (United States)

    Kim, Yongho

    2011-10-01

    The total T(d,g)5He/T(d,n)4He branching ratio of (4.5 +/- 0.5)E-5 has been measured on Inertial Confinement Fusion (ICF) implosions at the OMEGA laser facility. Recent measurements have shown that the DT branching ratio at ICF is 2 - 3 times less than that of previously measured at particle accelerator facilities. Measurements were done at ion temperatures of (5 +/- 2) keV, which is quite low compared to previous measurements. Implication of the recent founding is that nuclear properties such as DT branching ratio might be reconsidered at low temperature ICF and stellar conditions. In practical sense, precise measurements of the branching ratio T(d,g)5He relative to T(d,n)4He are important in order to diagnose target areal density and resultant fusion yield of cryogenically-layered implosions at the National Ignition Facility (NIF). In this work, we have used LANL's Gas Cherenkov Detector (GCD), which provides a high bandwidth, energy thresholding capability for gamma-ray detection using gamma/electron/Cherenkov conversion. High-bandwidth aids the detection of D-T fusion gamma rays before the arrival of associated 14.1 MeV neutron-induced gammas; energy thresholding gives further protection against such undesirable backgrounds. In addition, to reduce systematic uncertainty, we have applied three independent calibration methods to characterize GCD response such as (1) D-3He gamma-rays generated at Omega laser where no absolute detector calibration was required because quite similar gamma spectrum from D3He and DT, (2) mono-energetic gamma rays generated at Duke University's High Intensity Gamma-ray Source (HIgS), and (3) 14-MeV neutron-induced inelastic gamma-rays generated at OMEGA using puck materials of known areal density placed near target center. In conjunction with an independent neutron yield measurements and ACCEPT and GEANT4 simulation codes, the resultant DT branching ratio was inferred. This work was performed by Los Alamos National Laboratory under the

  17. Prevalence and features of ICF-disability in Spain as captured by the 2008 National Disability Survey

    Science.gov (United States)

    2011-01-01

    Background Since 1986, the study of disability in Spain has been mainly addressed by National Disability Surveys (NDSs). While international attempts to frame NDS designs within the International Classification of Functioning, Disability and Health (ICF) have progressed, in general, the ICF has hardly been used in either the NDS or epidemiological studies. This study sought to identify ICF Activity- and Participation-related content in the most recent Spanish NDS, the 2008 Survey on Disabilities, Independence and Dependency Situations (Encuesta sobre discapacidades, autonomía personal y situaciones de Dependencia - EDAD 2008), and estimate the prevalence of such ICF-framed disability. Methods EDAD 2008 methods and questions were perused. Of the 51 EDAD items analysed, 29 were backcoded to specific d2-d7 domains of the ICF Checklist and, by rating the recorded difficulty to perform specific tasks with or without help, these were then taken as performance and capacity respectively. A global ICF score was also derived, albeit lacking data for d1, "Learning and applying knowledge", d8, "Major Life Areas" and d9, "Community, Social and Civic Life". Data were grouped by sex, age, residence and initial positive screening, and prevalence figures were calculated by disability level both for the general population, using the originally designed weights, and for the population that had screened positive to disability. Data for institutionalised persons were processed separately. Results Crude prevalence of ICF severe/complete and moderate disability among the community-dwelling population aged ≥6 years was 0.9%-2.2% respectively, and that of severe/complete disability among persons living in sheltered accommodation was 0.3%. Prevalence of severe/complete disability was: higher in women than in men, 0.8% vs. 0.4%; increased with age; and was particularly high in domains such as "Domestic Life", 3.4%, "Mobility", 1.8%, and "Self-care", 1.9%, in which prevalence decreased

  18. The International Classification of Functioning, Disability and Health (ICF) Core Sets: application to a postmenopausal woman with rheumatoid arthritis and osteoporosis of the spine.

    Science.gov (United States)

    Lorbergs, Amanda L; MacIntyre, Norma J

    2013-10-01

    The International Classification of Functioning, Disability and Health (ICF) framework facilitates systematic assessment of functioning across four components. ICF Core Sets are proposed to be beneficial for clinicians in multidisciplinary care settings because they provide a common language for communication. A clinical vignette of a postmenopausal woman with rheumatoid arthritis (RA) and a non-traumatic vertebral fracture is presented to discuss how the ICF Core Sets for RA and osteoporosis (OP) can be helpful in structuring clinical decisions. To demonstrate how condition-specific ICF Core Sets can be used to evaluate and treat women with two comorbidities, each component of the ICF Core Sets is compared across conditions and integrated into clinical decision-making. Topics covered include: exercise tolerance, urinary continence, bone mass, fear of falling, and environmental factors. The benefits of thorough communication with the client and a common language across healthcare disciplines are highlighted as the potential benefits of the ICF framework; however, limitations to uptake of the ICF in clinical practice are also addressed.

  19. Dispersión sísmica por presencia de capas someras de alta velocidad: modelamiento con diferencias finitas

    Directory of Open Access Journals (Sweden)

    Céspedes Sandra

    2002-08-01

    estudia el efecto de la dispersion sísmica por la presencia de capas someras de alta velocidad, con contrastes y espesores variables, y su influencia en la información sísmica. A diferencia de los métodos convencionales de eliminacion de ruido de base fundamentalmente matemática, por ejemplo: F-K, Radón, se aplica un esquema determinístico basado en el modelamiento de propagación de ondas que reproduce las señales no deseadas (Ernst et al., 1998; Blonk et al., 1995; Blonk and Hermann, 1994. El entendimiento detallado del fenómeno que genera estas señales permite discernir lo que se considera ruido y, por tanto, definir estrategias para su atenuación (Lamer et al., 1983. Por la presencia de capas someras de alta velocidad, gran parte de la energía sísmica original se dispersa en estas capas y solo una pequeña fracción se transmite al interior de la Tierra, generando ruido coherente que enmascara la información proveniente de los reflectores mas profundos (Leslie and Evans, 1999. Se diseño un modelo 20 y se obtuvieron varios sismogramas sintéticos, La simulación muestra el mecanismo de dispersión relacionado con la inversion de velocidad en las capas mas someras, lo que permite caracterizar su influencia sobre los registros sísmicos. La información no deseada (ruido es sustraída de la que se considera información. Los resultados obtenidos en este trabajo se circunscriben al análisis de datos sintéticos.

  20. ONDAS DE MONTAÑA EN LA CAPA LÍMITE PLANETARIA DE LA REGIÓN ANDINA VENEZOLANA

    Directory of Open Access Journals (Sweden)

    HÉCTOR VÁSQUEZ

    2015-09-01

    Full Text Available Se evalúa las condiciones dinámicas y termodinámicas de la capa límite planetaria de la Región Andina Venezolana para la génesis de ondas de montaña. Para ello se calcula el número de Froude relacionando la estabilidad estática en presencia de accidentes orográficos con apoyo de perfiles verticales de viento, análisis de diagramas termodinámicos e imágenes de satélite. Se encuentra que cuando se presenta un flujo de aire perpendicular a la cordillera andina venezolana con vientos mayores a 10 m/s bajo condiciones de estabilidad o inversión de temperatura sobre su cima, disponibilidad de humedad mayor a 70% desde superficie a su cumbre y numero de Froude ligeramente superior a 1, el resultado es la presencia de ondas de montaña asociadas a nubes lenticulares a sotavento de la cadena montañosa.

  1. Validation of the Italian version of Mini-ICF-APP, a short instrument for rating activity and participation restrictions in psychiatric disorders.

    Science.gov (United States)

    Balestrieri, M; Isola, M; Bonn, R; Tam, T; Vio, A; Linden, M; Maso, E

    2013-03-01

    Aims. The assessment of limitations in social capacities can be done with the Mini-ICF-APP, a rating scale built in reference to the International Classification of Functioning, Disability and Health (ICF). The aim of this study was to assess the reliability and the convergent validity of the Italian version of this scale. Methods. We recruited 120 consecutive patients diagnosed with schizophrenia, major depression, bipolar I disorder and anxiety disorders. Included measures were the Brief Psychiatric Rating Scale (BPRS), the Clinical Global Impression Scale (CGI-S), the Personal and Social Performance Scale (PSP) and the Social and Occupational Functioning Assessment Scale (SOFAS). Results. The median CGI-S and BPRS scores were 5 and 16.5. Mean Mini-ICF-APP total score was 18.1. Schizophrenics' Mini-ICF-APP score was higher, while that of anxious patients was lower than in the other diagnoses. Intra-class correlations (ICC) revealed a significant inter-rater agreement for total score (ICC 0.987) and for each item of the Mini-ICF-APP. The test-retest agreement was also highly significant (ICC 0.993). The total score of the Mini-ICF-APP obtained good negative correlations with PSP (r s = -0.767) and with SOFAS scores (r s = -0.790). The distribution items of the Mini-ICF-APP showed some skewness, indicating that self-care (item 12) and mobility (item 13) were amply preserved in most patients. The Mini-ICF-APP total score was significantly correlated with both CGI-S (r s = 0.777) and BPRS (r s = 0.729). Conclusions. As a short instrument, the Mini-ICF-APP scale seems to be well suited to everyday psychiatric practice as a means of monitoring changes in psychosocial functioning, in particular in schizophrenic patients.

  2. A coordinate transformation method for calculating the 3D light intensity distribution in ICF hohlraum

    Science.gov (United States)

    Lin, Zhili; Li, Xiaoyan; Zhao, Kuixia; Chen, Xudong; Chen, Mingyu; Pu, Jixiong

    2016-06-01

    For an inertial confinement fusion (ICF) system, the light intensity distribution in the hohlraum is key to the initial plasma excitation and later laser-plasma interaction process. Based on the concept of coordinate transformation of spatial points and vector, we present a robust method with a detailed procedure that makes the calculation of the three dimensional (3D) light intensity distribution in hohlraum easily. The method is intuitive but powerful enough to solve the complex cases of random number of laser beams with arbitrary polarization states and incidence angles. Its application is exemplified in the Shenguang III Facility (SG-III) that verifies its effectiveness and it is useful for guiding the design of hohlraum structure parameter.

  3. Neutron Signatures of Non-Thermal Ion Distributions in Z-Pinch Driven ICF Plasmas

    Science.gov (United States)

    Knapp, Patrick; Jennings, Christopher; Sinars, Daniel

    2012-10-01

    In preparation for upcoming ICF experiments on the 26 MA Z machine (e.g., D2 gas puff, MagLIF [1]), we are studying the neutron energy spectra produced by magnetically-driven loads beyond the archetypal single temperature, uniform plasma. Z-pinch sources frequently exhibit evidence of unusual neutron spectra [2], which can be attributed to three-dimensional turbulent motion, high-energy beams, and other phenomena leading to non-Maxwellian ion distributions. Understanding the nature of our plasma neutron sources is critical for understanding how they scale with increasing current. We will show Monte Carlo and analytic calculations for plausible scenarios and discuss the corresponding signatures for the existing set of time-of-flight diagnostics on Z.[4pt] [1] S. A. Slutz et al. Phys. Plasmas 17, 056303 (2010)[0pt] [2] V.V. Vikhrev and V.D. Korolev, Plasma Dynamics, Vol. 33, No. 5 (2007)

  4. Status of Indirect Drive ICF Experiments on the National Ignition Facility

    Energy Technology Data Exchange (ETDEWEB)

    Dewald, E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-03-21

    In the quest to demonstrate Inertial Confinement Fusion (ICF) ignition of deuterium-tritium (DT) filled capsules and propagating thermonuclear burn with net energy gain (fusion energy/laser energy >1), recent experiments on the National Ignition Facility (NIF) have shown progress towards increasing capsule hot spot temperature (Tion>5 keV) and fusion neutron yield (~1016), while achieving ~2x yield amplification by alpha particle deposition. At the same time a performance cliff was reached, resulting in lower fusion yields than expected as the implosion velocity was increased. Ongoing studies of the hohlraum and capsule physics are attempting to disseminate possible causes for this performance ceiling.

  5. Wavelets, Curvelets and Multiresolution Analysis Techniques Applied to Implosion Symmetry Characterization of ICF Targets

    CERN Document Server

    Afeyan, Bedros; Starck, Jean Luc; Cuneo, Michael

    2012-01-01

    We introduce wavelets, curvelets and multiresolution analysis techniques to assess the symmetry of X ray driven imploding shells in ICF targets. After denoising X ray backlighting produced images, we determine the Shell Thickness Averaged Radius (STAR) of maximum density, r*(N, {\\theta}), where N is the percentage of the shell thickness over which to average. The non-uniformities of r*(N, {\\theta}) are quantified by a Legendre polynomial decomposition in angle, {\\theta}. Undecimated wavelet decompositions outperform decimated ones in denoising and both are surpassed by the curvelet transform. In each case, hard thresholding based on noise modeling is used. We have also applied combined wavelet and curvelet filter techniques with variational minimization as a way to select the significant coefficients. Gains are minimal over curvelets alone in the images we have analyzed.

  6. Large Survey of Neutron Spectrum Moments Due to ICF Drive Asymmetry

    Science.gov (United States)

    Field, J. E.; Munro, D.; Spears, B.; Peterson, J. L.; Brandon, S.; Gaffney, J. A.; Hammer, J.; Langer, S.; Nora, R. C.; Springer, P.; ICF Workflow Collaboration Collaboration

    2016-10-01

    We have recently completed the largest HYDRA simulation survey to date ( 60 , 000 runs) of drive asymmetry on the new Trinity computer at LANL. The 2D simulations covered a large space of credible perturbations to the drive of ICF implosions on the NIF. Cumulants of the produced birth energy spectrum for DD and DT reaction neutrons were tallied using new methods. Comparison of the experimental spectra with our map of predicted spectra from simulation should provide a wealth of information about the burning plasma region. We report on our results, highlighting areas of agreement (and disagreement) with experimental spectra. We also identify features in the predicted spectra that might be amenable to measurement with improved diagnostics. Prepared by LLNL under Contract DE-AC52-07NA27344. IM release #: LLNL-PROC-697321.

  7. Using absolute x-ray spectral measurements to infer stagnation conditions in ICF implosions

    Science.gov (United States)

    Patel, Pravesh; Benedetti, L. R.; Cerjan, C.; Clark, D. S.; Hurricane, O. A.; Izumi, N.; Jarrott, L. C.; Khan, S.; Kritcher, A. L.; Ma, T.; Macphee, A. G.; Landen, O.; Spears, B. K.; Springer, P. T.

    2016-10-01

    Measurements of the continuum x-ray spectrum emitted from the hot-spot of an ICF implosion can be used to infer a number thermodynamic properties at stagnation including temperature, pressure, and hot-spot mix. In deuterium-tritium (DT) layered implosion experiments on the National Ignition Facility (NIF) we field a number of x-ray diagnostics that provide spatial, temporal, and spectrally-resolved measurements of the radiated x-ray emission. We report on analysis of these measurements using a 1-D hot-spot model to infer thermodynamic properties at stagnation. We compare these to similar properties that can be derived from DT fusion neutron measurements. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  8. Experimental techniques for measuring Rayleigh-Taylor instability in inertial confinement fusion (ICF)

    Energy Technology Data Exchange (ETDEWEB)

    Smalyuk, V A

    2012-06-07

    Rayleigh-Taylor (RT) instability is one of the major concerns in inertial confinement fusion (ICF) because it amplifies target modulations in both acceleration and deceleration phases of implosion, which leads to shell disruption and performance degradation of imploding targets. This article reviews experimental results of the RT growth experiments performed on OMEGA laser system, where targets were driven directly with laser light. RT instability was studied in the linear and nonlinear regimes. The experiments were performed in acceleration phase, using planar and spherical targets, and in deceleration phase of spherical implosions, using spherical shells. Initial target modulations consisted of 2-D pre-imposed modulations, and 2-D and 3-D modulations imprinted on targets by the non-uniformities in laser drive. In planar geometry, the nonlinear regime was studied using 3-D modulations with broadband spectra near nonlinear saturation levels. In acceleration-phase, the measured modulation Fourier spectra and nonlinear growth velocities are in good agreement with those predicted by Haan's model [Haan S W 1989 Phys. Rev. A 39 5812]. In a real-space analysis, the bubble merger was quantified by a self-similar evolution of bubble size distributions [Oron D et al 2001 Phys. Plasmas 8, 2883]. The 3-D, inner-surface modulations were measured to grow throughout the deceleration phase of spherical implosions. RT growth rates are very sensitive to the drive conditions, therefore they can be used to test and validate drive physics in hydrodynamic codes used to design ICF implosions. Measured growth rates of pre-imposed 2-D target modulations below nonlinear saturation levels were used to validate non-local thermal electron transport model in laser-driven experiments.

  9. Large-scale 3D simulations of ICF and HEDP targets

    Science.gov (United States)

    Marinak, Michael M.

    2000-10-01

    The radiation hydrodynamics code HYDRA continues to be developed and applied to 3D simulations of a variety of targets for both inertial confinement fusion (ICF) and high energy density physics. Several packages have been added enabling this code to perform ICF target simulations with similar accuracy as two-dimensional codes of long-time historical use. These include a laser ray trace and deposition package, a heavy ion deposition package, implicit Monte Carlo photonics, and non-LTE opacities, derived from XSN or the linearized response matrix approach.(R. More, T. Kato, Phys. Rev. Lett. 81, 814 (1998), S. Libby, F. Graziani, R. More, T. Kato, Proceedings of the 13th International Conference on Laser Interactions and Related Plasma Phenomena, (AIP, New York, 1997).) LTE opacities can also be calculated for arbitrary mixtures online by combining tabular values generated by different opacity codes. Thermonuclear burn, charged particle transport, neutron energy deposition, electron-ion coupling and conduction, and multigroup radiation diffusion packages are also installed. HYDRA can employ ALE hydrodynamics; a number of grid motion algorithms are available. Multi-material flows are resolved using material interface reconstruction. Results from large-scale simulations run on up to 1680 processors, using a combination of massively parallel processing and symmetric multiprocessing, will be described. A large solid angle simulation of Rayleigh-Taylor instability growth in a NIF ignition capsule has resolved simultaneously the full spectrum of the most dangerous modes that grow from surface roughness. Simulations of a NIF hohlraum illuminated with the initial 96 beam configuration have also been performed. The effect of the hohlraum’s 3D intrinsic drive asymmetry on the capsule implosion will be considered. We will also discuss results from a Nova experiment in which a copper sphere is crushed by a planar shock. Several interacting hydrodynamic instabilities, including

  10. Simulation of near-surface layer of the colombian pacific ocean

    OpenAIRE

    Karlin Lev; Villegas Nancy

    2011-01-01

    Este artículo muestra los resultados obtenidos en el estudio de la estructura fina termohalina de la capa sub-superficial realizado en la Cuenca del Pacífico colombiano. Se formularon modelos matemáticos para diferentes regímenes de capas sub-superficiales. Basado en tres estaciones se realizó un análisis horario de información meteorológica, variación de espesor, temperatura y salinidad de la capa fina. Las leyes de formación de la estructura fina termohalina para la capa sub-superficial en ...

  11. La cerámica romana de paredes finas del Santuario de So n'Oms, Palma de Mallorca. Nuevas producciones de Mallorca e Ibiza

    Directory of Open Access Journals (Sweden)

    López Mullor, Alberto

    2001-12-01

    Full Text Available Inside the talayotic complex known as So n'Oms, in the municipal area of Palma (Mallorca, Balearic Islands, there is a sanctuary excavated in the sixties which produced an ample series of thin walled pottery that were dedicated as offerings to the gods. All the material found can be dated between 20-10 a.C.-. and 50 d.C. It is so well preserved that it has been possible to recognise and determine decoration and paste and, therefore, to reach to the conclusion that most of them belongs to production centers situated in Mallorca and Ibiza (from this last almost the 70%. There are, also, italic and betican productions.Dentro del conjunto talayótico conocido como So n'Oms, situado en el término municipal de Palma (Mallorca, islas Baleares, existe un santuario excavado en la década de los sesenta, que proporcionó un extenso lote de cerámica de paredes finas, depositadas allí como ofrenda. Los materiales pueden situarse entre los años 20/10 a.C. y 50 de nuestra era. Destaca su buen estado de conservación, que ha permitido un reconocimiento minucioso de pastas y decoraciones, habiéndose podido atribuir una gran parte de las piezas a centros productores de Mallorca y sobre todo —más del 70 %— de Ibiza. También se han localizado vasos héticos e itálicos.

  12. A comprehensive scoping review of ability and disability in ADHD using the International Classification of Functioning, Disability and Health-Children and Youth Version (ICF-CY).

    Science.gov (United States)

    de Schipper, Elles; Lundequist, Aiko; Wilteus, Anna Löfgren; Coghill, David; de Vries, Petrus J; Granlund, Mats; Holtmann, Martin; Jonsson, Ulf; Karande, Sunil; Levy, Florence; Al-Modayfer, Omar; Rohde, Luis; Tannock, Rosemary; Tonge, Bruce; Bölte, Sven

    2015-08-01

    This is the first in a series of four empirical investigations to develop International Classification of Functioning, Disability and Health (ICF) Core Sets for Attention Deficit Hyperactivity Disorder (ADHD). The objective here was to use a comprehensive scoping review approach to identify the concepts of functional ability and disability used in the scientific ADHD literature and link these to the nomenclature of the ICF-CY. Systematic searches were conducted using Medline/PubMed, PsycINFO, ERIC and Cinahl, to extract the relevant concepts of functional ability and disability from the identified outcome studies of ADHD. These concepts were then linked to ICF-CY by two independent researchers using a standardized linking procedure. Data from identified studies were analysed until saturation of ICF-CY categories was reached. Eighty studies were included in the final analysis. Concepts contained in these studies were linked to 128 ICF-CY categories. Of these categories, 68 were considered to be particularly relevant to ADHD (i.e., identified in at least 5 % of the studies). Of these, 32 were related to Activities and participation, 31 were related to Body functions, and five were related to environmental factors. The five most frequently identified categories were school education (53 %), energy and drive functions (50 %), psychomotor functions (50 %), attention functions (49 %), and emotional functions (45 %). The broad variety of ICF-CY categories identified in this study underlines the necessity to consider ability and disability in ADHD across all dimensions of life, for which the ICF-CY provides a valuable and universally applicable framework. These results, in combination with three additional preparatory studies (expert survey, focus groups, clinical study), will provide a scientific basis to define the ICF Core Sets for ADHD for multi-purpose use in basic and applied research, and every day clinical practice.

  13. Clinical comparison of the Bactec Mycosis IC/F, BacT/Alert FA, and BacT/Alert FN blood culture vials for the detection of candidemia.

    Science.gov (United States)

    Ericson, Eva-Lena; Klingspor, Lena; Ullberg, Måns; Ozenci, Volkan

    2012-06-01

    The present study analyzed the performance of Bactec Mycosis IC/F, BacT/Alert FA, and BacT/Alert FN vials in detection and time to detection (TTD) of Candida spp. in 179 simultaneous blood cultures. The Mycosis IC/F, BacT/Alert FA, and BacT/Alert FN vials could detect Candida spp. in 144 (80.45%) of 179, 149 (83.24%) of 179, and 8 (4.47%) of 179 samples, respectively. With the presence of antifungal therapy, the numbers of positive vials were higher in BacT/Alert FA compared to Mycosis IC/F, 87/99 versus 73/99, respectively (P IC/F than in BacT/Alert FA vials without antifungal therapy, 20.89 (9.33) versus 28.26 (9.77), respectively (P IC/F than in BacT/Alert FA vials, 28/30 and 19/30, respectively (P = 0.01). The present data show that the use of Bactec Mycosis IC/F together with BacT/Alert FA vials might improve the detection of Candida spp.

  14. The use of the international classification of functioning, disability and health (ICF) in indigenous healthcare: a systematic literature review

    OpenAIRE

    Alford, Vanessa M; Remedios, Louisa J; Webb, Gillian R; Ewen, Shaun

    2013-01-01

    Introduction The International Classification of Functioning, Disability and Health (ICF) was endorsed by the World Health Organisation (WHO) in 2001 to obtain a comprehensive perspective of health and functioning of individuals and groups. Health disparities exist between Indigenous and non-Indigenous Australians and there is a need to understand the health experiences of Indigenous communities from Indigenous Australian’s perspectives in order to develop and implement culturally appropriate...

  15. Target Diagnostic Technology Research and Development for the LLNL ICF and HED Programs

    Energy Technology Data Exchange (ETDEWEB)

    Bell, P; Bennett, C; Holder, J; Kimbrough, J; Landen, O; Lerche, D; Lowry, M; McDonald, J; Perry, T; Turner, B; Weber, F

    2003-08-22

    The National Ignition Facility (NIF) is under construction at LLNL for the Department of Energy Stockpile Stewardship Program. It will be used for experiments for Inertial Confinement Fusion (ICF) Ignition, High Energy Density (HED) science, and basic science. Many issues confront experimentalists who wish to design, fabricate, and install diagnostics on the NIF. To foster this process the ICF and HED programs at LLNL have formed a diagnostic research and development group to look at issues outside the charter of facility diagnostics (core diagnostics). We will present data from instrumentation and associated technology that is being developed by this group. A major portion of our instrumentation work is on improvements for readout systems. We have several efforts related to CCD device development. Work has been done in collaboration with the University of Arizona to backthin a large format CCD device (36mm{sup 2}). This work has shown good results. The device has very high quantum efficiency, low noise readout and high charge transfer efficiency. The device is being fielded in direct optical, direct x-ray and 13-15 RV electron readout applications. In addition to readout device development we have completed work on a CCD readout system. With a commercial vendor we have developed a large format, compact, Ethernet addressable CCD camera system. This system fits in shoebox size volume, is thermal electrically cooled, supports a variety of CCD devices and can be run from remote locations via TCP/IP protocol. We are also doing work to improve streak camera systems. We have coupled our large format CCD system to an MK2 Kentech streak tube. Improvements have been made to the resolution and dynamic range of the system. Similar improvements have been made to the LLNL optical streak camera systems. We will present data from the optical and x-ray streak camera work. In addition we will present data from single shot high-speed, high dynamic range data link work. In

  16. Global Functioning of COPD Patients With and Without Functional Balance Impairment: An Exploratory Analysis Based on the ICF Framework.

    Science.gov (United States)

    Cruz, Joana; Marques, Alda; Jácome, Cristina; Gabriel, Raquel; Figueiredo, Daniela

    2015-04-01

    Balance impairment is a common manifestation in older people with COPD and may contribute to overall functional decline; however, the relationship between balance and global functioning has not been studied. This study aimed to explore the global functioning of COPD patients with and without functional balance impairment. Functional balance was assessed with the Timed Up-and-Go (TUG) test and global functioning with the Comprehensive ICF Core Set for Obstructive Pulmonary Diseases. Participants (n = 134) were divided in 2 groups according to their performance in TUG (with and without balance impairment) and the ICF Core Set results were compared between groups. Fifty-four (40.3%) participants had functional balance impairment. The groups presented a similar extent of problems in several categories of the ICF components. However, participants with balance impairment were more severely affected (p social life, and a more negative perception of Environmental factors related to products and technology of buildings for private use and social support services (p balance impairment have more functional problems and are more severely restricted in daily life than patients without compromised balance. Understanding the relationship between balance control and global functioning will contribute to guide interventions aimed at maintaining functioning and minimizing disability.

  17. Isolation, cloning, and expression mapping of a gene encoding an antidiuretic hormone and other CAPA-related peptides in the disease vector, Rhodnius prolixus.

    Science.gov (United States)

    Paluzzi, Jean-Paul; Russell, William K; Nachman, Ronald J; Orchard, Ian

    2008-09-01

    After a blood meal, Rhodnius prolixus undergoes a rapid diuresis to eliminate excess water and salts. During the voiding of this primary urine, R. prolixus acts as a vector of Chagas' disease, with the causative agent, Trypanosoma cruzi, infecting the human host via the urine. Diuresis in R. prolixus is under the neurohormonal control of serotonin and peptidergic diuretic hormones, and thus, diuretic hormones play an important role in the transmission of Chagas' disease. Although diuretic hormones may be degraded or excreted, resulting in the termination of diuresis, it would also seem appropriate, given the high rates of secretion, that a potent antidiuretic factor could be present and act to prevent excessive loss of water and salts after the postgorging diuresis. Despite the medical importance of R. prolixus, no genes for any neuropeptides have been cloned, including obviously, those that control diuresis. Here, using molecular biology in combination with matrix-assisted laser desorption ionization-time of flight-tandem mass spectrometry, we determined the sequence of the CAPA gene and CAPA-related peptides in R. prolixus, which includes a peptide with anti-diuretic activity. We have characterized the expression of mRNA encoding these peptides in various developmental stage and also examined the tissue-specific distribution in fifth-instars. The expression is localized to numerous bilaterally paired cell bodies within the central nervous system. In addition, our results show that RhoprCAPA gene expression is also associated with the testes, suggesting a novel role for this family of peptides in reproduction.

  18. Caracterización de la distribución de la biomasa y densidad de raíces finas en un gradiente sucesional de bosques en la Zona Norte de Costa Rica.

    OpenAIRE

    Jiménez-Rodríguez, César

    2004-01-01

    Informe Final de Proyecto de Investigación. En este estudio se evaluó la distribución de la biomasa radical, el índice de área radical (RAI) y la densidad longitudinal (RLD) de raíces finas (< 5 mm) en una gradiente sucesional de bosques húmedos tropicales en la zona de Florencia de San Carlos, Costa Rica. La variación de estos parámetros se evaluaron en función de la profundidad del suelo y del estado sucesional. La biomasa radical al igual que el RAI y el RLD disminuyen conforme aumenta ...

  19. Análise numérica do comportamento mecânico sob flexão de placas finas de material compósito laminado reforçado por fibras

    OpenAIRE

    Helbig, Daniel; Real, Mauro de Vasconcellos; Rocha, Luiz Alberto Oliveira; Santos, Elizaldo Domingues dos; Isoldi, Liércio André

    2013-01-01

    A crescente necessidade de estruturas com propriedades mecânicas superiores impulsiona o desenvolvimento de novos tipos de materiais, dentre os quais se destacam os materiais compósitos laminados reforçados por fibras. Placas finas construídas com estes materiais possuem diversas vantagens em comparação com as fabricadas com materiais de construção mecânica convencionais como o aço: altas relações rigidez/peso e resistência/peso; alta resistência à fadiga; e excelente resistência à corrosão. ...

  20. Relación entre el nivel de motricidad fina y remoción de placa bacteriana a través del cepillado manual en niños

    OpenAIRE

    Macote Orosco, Lisbeth Melchora

    2015-01-01

    Introducción: En la eficacia del cepillado intervienen múltiples factores como el tiempo, zonas a cepillar y habilidades motoras de la persona. ¿El niñ@ de cinco años de edad tiene las habilidades motoras pra realizar un cepillado dental eficaz?.Objetivos: Determinar la relación entre el nivel de motricidad fina y la remoción de placa bacteriana a través del cepillado manual en niñ@s de 5 años de edad. determinar la higiene oral antes y después del cepillado, relacionar el nivel de motricidad...

  1. Relación entre el nivel de motricidad fina y remoción de placa bacteriana a través del cepillado manual en niños

    OpenAIRE

    Macote Orosco, Lisbeth Melchora

    2016-01-01

    Introducción: En la eficacia del cepillado intervienen múltiples factores como el tiempo, zonas a cepillar y habilidades motoras de la persona. ¿El niñ@ de cinco años de edad tiene las habilidades motoras pra realizar un cepillado dental eficaz?.Objetivos: Determinar la relación entre el nivel de motricidad fina y la remoción de placa bacteriana a través del cepillado manual en niñ@s de 5 años de edad. determinar la higiene oral antes y después del cepillado, relacionar el nivel de motricidad...

  2. Tratamiento de suelos con cal y/o conglomerantes hidraulicos : Aplicacion a la construccion de terraplenes y capas de forma : Manual técnico

    OpenAIRE

    2005-01-01

    Este manual técnico codifica la técnica del tratamiento de suelos con cal y/o conglomerantes hidráulicos utilizada para la construcción de terraplenes y de capas de forma de carreteras en Francia. La primera parte del presente manual recapitula las generalidades relativas a los suelos, la cal aérea, los conglomerantes hidráulicos y a las interacciónes que se producen entre aquellos materiales. El conocimiento de estas generalidades resulta imprescindible para la comprensión de los elementos q...

  3. GÉNEROS BACTERIANOS DOMINANTES EN LOS ESTRATOS FOLIARES DEL TABACO CURADO PARA CAPAS. INFLUENCIA DE LA NICOTINA Y EL pH SOBRE SU DENSIDAD POBLACIONAL

    OpenAIRE

    Yunior M. Morán Gómez; Daylin Fleitas Gutiérrez; Rosario Domínguez Larrinaga; Martín M. Cuervo Fernández; José M. Guardiola Pedroso; Isabel Márquez Leyva

    2013-01-01

    Aunque las bacterias juegan un papel importante en el proceso fermentativo del tabaco, en Cuba no se han identificado los géneros presentes en el tabaco curado para capas, ni las variables que afectan a sus poblaciones. Este conocimiento pudiera contribuir al manejo de los procesos en los que estos microorganismos intervienen. El objetivo de esta investigación fue determinar la relación que existe entre la densidad poblacional de los géneros bacterianos dominantes en los diferentes estratos f...

  4. 9th GCC closed forum: CAPA in regulated bioanalysis; method robustness, biosimilars, preclinical method validation, endogenous biomarkers, whole blood stability, regulatory audit experiences and electronic laboratory notebooks.

    Science.gov (United States)

    Hayes, Roger; LeLacheur, Richard; Dumont, Isabelle; Couerbe, Philippe; Safavi, Afshin; Islam, Rafiq; Pattison, Colin; Cape, Stephanie; Rocci, Mario; Briscoe, Chad; Cojocaru, Laura; Groeber, Elizabeth; Silvestro, Luigi; Bravo, Jennifer; Shoup, Ron; Verville, Manon; Zimmer, Jennifer; Caturla, Maria Cruz; Khadang, Ardeshir; Bourdage, James; Hughes, Nicola; Fatmi, Saadya; Di Donato, Lorella; Sheldon, Curtis; Keyhani, Anahita; Satterwhite, Christina; Yu, Mathilde; Fiscella, Michele; Hulse, James; Lin, Zhongping John; Garofolo, Wei; Savoie, Natasha; Xiao, Yi Qun; Kurylak, Kai; Harris, Sarah; Saxena, Manju; Buonarati, Mike; Lévesque, Ann; Boudreau, Nadine; Lin, Jenny; Khan, Masood U; Ray, Gene; Liu, Yansheng; Xu, Allan; Soni, Gunjan; Ward, Ian; Kingsley, Clare; Ritzén, Hanna; Tabler, Edward; Nicholson, Bob; Bennett, Patrick; van de Merbel, Nico; Karnik, Shane; Bouhajib, Mohammed; Wieling, Jaap; Mulvana, Daniel; Ingelse, Benno; Allen, Mike; Malone, Michele; Fang, Xinping

    2016-03-01

    The 9th GCCClosed Forum was held just prior to the 2015 Workshop on Recent Issues in Bioanalysis (WRIB) in Miami, FL, USA on 13 April 2015. In attendance were 58 senior-level participants, from eight countries, representing 38 CRO companies offering bioanalytical services. The objective of this meeting was for CRO bioanalytical representatives to meet and discuss scientific and regulatory issues specific to bioanalysis. The issues selected at this year's closed forum include CAPA, biosimilars, preclinical method validation, endogenous biomarkers, whole blood stability, and ELNs. A summary of the industry's best practices and the conclusions from the discussion of these topics is included in this meeting report.

  5. Caracterización de la doble capa eléctrica en las fibras textiles y su influencia en la absorción de tensioactivos.

    OpenAIRE

    Carrión Fité, Francisco Javier

    1986-01-01

    Para caracterizar la doble capa eléctrica se cuantifican las fuerzas de interacción electrostática entre la superficie de la fibra cargada y los iones de los electrolitos que la rodean, lográndose ésto a partir de determinaciones electrocinéticas de potencial. Se inicia el tema indicando el origen de la carga en la superficie de la fibra textil, al ponerse en contacto con un medio polar. Seguidamente, se procede a mostrar la influencia que la citada carga de superficie tiene en la soluc...

  6. Estudio de "las capas del cabo ladrillero superior" en el cabo homónimo, mioceno inferior de la cuenca austral, tierra del fuego

    Directory of Open Access Journals (Sweden)

    Estefanía P Tudisca

    2012-03-01

    Full Text Available En los acantilados del cabo Ladrillero, situado sobre la costa atlántica de la Isla Grande de Tierra del Fuego, afloran parte de los depósitos cuspidales que rellenan la cuenca de antepaís Austral o de Magallanes. Estos depósitos del Mioceno inferior son conocidos como "capas del Cabo Ladrillero" y "capas del Cabo San Pablo", siendo las "capas del Cabo Ladrillero superior" las analizadas en este trabajo. La zona de estudio, situada a una decena de kilómetros al norte del frente orogénico emergente (Punta Gruesa, permitió reconocer cuatro asociaciones de facies que registran depósitos gravitacionales resedimentados en un ambiente marino supra batial y una cuña deltaica progradante y somerizante hacia el noreste. Entre los rasgos más conspicuos observados en esta sucesión se destacan bancos deformados, intervalos macizos y abundantes diques clásticos, cuyo análisis estadístico indica un patrón transtensivo. Los microfósiles documentados en el área y utilizados previamente como herramienta para sostener un ambiente marino profundo provienen de niveles estratigráficos infrayacentes y corresponden a niveles de la Formación Desdémona y las capas del Cabo Ladrillero inferior, aflorantes hacia el sur de la zona de estudio. Las evidencias sedimentológicas no son concluyentes respecto de la batimetría, pero la ausencia de turbiditas clásicas, flujos hiperpícnicos, la abundancia de bancos deformados y resedimentados, restos vegetales y fragmentos de carbón son compatibles con un ambiente somero y deltaico con altas tasas de aporte y pendientes inestables antes que un ambiente marino profundo, y sugieren una historia compleja de la evolución del relleno sedimentario que no se explica meramente con los esquemas basados exclusivamente en el contenido de foraminíferos que domina en la literatura.

  7. Recém-nascido pequeno para a idade gestacional: repercussão nas habilidades motoras finas Pequeño para la edad gestacional: repercusión en las habilidades motoras finas Small-for-gestational-age newborn infant: repercussion on fine motor skills

    Directory of Open Access Journals (Sweden)

    Amabile Vessoni Arias

    2011-03-01

    Full Text Available OBJETIVO: Comparar as habilidades motoras finas de lactentes nascidos a termo pequenos para a idade gestacional (PIG com as habilidades dos nascidos adequados para a idade gestacional (AIG no terceiro mês de vida. MÉTODOS: Realizou-se um estudo observacional de corte transversal. Avaliaram-se 67 lactentes (21 PIG e 46 AIG no terceiro mês de vida. Portadores de síndromes genéticas, malformações congênitas, infecções congênitas e aqueles que necessitaram de unidade de terapia intensiva neonatal foram excluídos. As Escalas Bayley II de Desenvolvimento Infantil foram utilizadas, com ênfase nos itens que avaliam as habilidades motoras finas. RESULTADOS: Não se observaram diferenças entre os grupos na escala motora (p=0,21 e mental (p=0,45 no terceiro mês de vida. No item "Alcança o Aro Suspenso", houve diferença significativa (teste Exato de Fisher; p=0,02, demonstrando maior frequência de execução para o grupo PIG no terceiro mês de vida. CONCLUSÕES: Supõe-se que a diferença encontrada no item "Alcança o Aro Suspenso" possa ser atribuída à grande ocorrência de movimentos dos braços observada no grupo PIG e não a uma condição melhor de desenvolvimento desse grupo.OBJETIVO: Comparar las habilidades motoras finas de lactantes nacidos a término pequeños para la edad gestacional (PEG con adecuados para la edad gestacional (AEG en el 3er mes de vida. MÉTODOS: Se realizó un estudio observacional de corte transversal. Se evaluaron a 67 lactantes (21 PEG y 46 AEG en el 3er mes de vida. Síndromes genéticos, malformaciones congénitas, infecciones congénitas y aquellos que necesitaron de unidad de terapia intensiva neonatal fueron excluidos. Las Escalas Bayley II y de Desarrollo Infantil fueron utilizadas, con énfasis en los ítems que evalúan las habilidades motoras finas. RESULTADOS: No se observaron diferencias entre los grupos en la escala motora (p=0,21 y mental (p=0,45 en el 3er mes de vida. En el ítem "alcanza

  8. Estudio del comportamiento durante la sinterización de mezclas WC-Co finas, ultrafinas y nanocristalinas obtenidas por molienda de alta energía

    Directory of Open Access Journals (Sweden)

    Salvador, M. D.

    2008-10-01

    Full Text Available In this work the sintering behaviour of fine, ultrafine and nanocrystalline WC-12Co mixtures obtained by high energy milling, as well as commercial nanopowders, have been studied, in order to evaluate the effect of the particle size and the powder processing, in the densification, microstructural development and mechanical properties of the final product. The consolidation of the mixtures has been made by uniaxial pressing and sintering in vacuum, and by hot isostatic pressing. The sintered materials have been evaluated by measures of density, hardness and indentation fracture toughness, and microstructurally characterized by optical microscopy and scanning and transmission electronic microscopy (SEM and TEM. The results show the improvements in resistant behaviour of the materials obtained from nanocrystalline powders, in spite of the grain growth experienced during the sintering. The best results were obtained for the milling nanocrystalline material, which presents values of hardness higher than 1800 HV.

    En este trabajo se ha estudiado el comportamiento, durante la sinterización, de mezclas WC-12Co finas, ultrafinas y nanométricas obtenidas por molienda de alta energía y de material nanométrico comercial, a fin de evaluar el efecto del tamaño de partícula y del proceso de obtención del polvo en la densificación, desarrollo microestructural y propiedades mecánicas del producto final. La consolidación de las mezclas se ha realizado mediante compactación uniaxial y sinterización en vacío y por compactación isostática en caliente. Los materiales sinterizados se han evaluado mediante medidas de densidad, dureza y tenacidad a fractura por indentación y se han caracterizado microestructuralmente mediante microscopía óptica y microscopía electrónica de barrido y de transmisión. Los resultados obtenidos ponen de manifiesto las mejoras en comportamiento resistente de los materiales obtenidos a partir polvos nanométricos, a

  9. Fatores Associados ao Material Insuficiente em Punção Aspirativa por Agulha Fina nos Nódulos Sólidos da Mama

    Directory of Open Access Journals (Sweden)

    Freitas Júnior Ruffo de

    2001-01-01

    Full Text Available Objetivo: analisar alguns fatores que possam estar associados à ocorrência de material insuficiente nos aspirados da punção aspirativa por agulha fina (PAAF. Pacientes e Métodos: foram estudadas 351 citologias de pacientes com nódulos sólidos da mama, submetidas a PAAF, como parte de sua investigação diagnóstica. As lâminas foram analisadas por um único citologista, que classificou os esfregaços como malignos, suspeitos, benignos ou material insuficiente para diagnóstico. Foram avaliados a idade da paciente, o tamanho do tumor, o estádio clínico, o Serviço, o dispositivo utilizado na punção e o tipo de lesão puncionada, de acordo com a histologia. A significância de cada variável em relação ao material insuficiente foi testada pelo c². Resultados: houve 67 esfregaços classificados como material insuficiente (19%. O tipo de dispositivo utilizado, o tamanho do tumor, o Serviço e o estádio clínico das lesões não se relacionaram à quantidade de material suficiente ou insuficiente. A idade da paciente e o tipo histológico influenciaram a taxa de material insuficiente, sendo que as pacientes abaixo de 50 anos tiveram uma taxa de 12%, comparada a 30% daquelas acima de 50 anos (p<0,03. Quanto à histologia, nas pacientes com alterações funcionais benignas da mama, a taxa de material insuficiente foi de 30%, seguida daquelas com carcinoma ductal infiltrante, 20%, e, no fibroadenoma, 12% (p<0,02. Conclusão: esse estudo mostrou uma taxa de material insuficiente relativamente alta (19%, a qual foi influenciada pela idade da paciente e pelo tipo histológico da lesão.

  10. ND:GLASS LASER DESIGN FOR LASER ICF FISSION ENERGY (LIFE)

    Energy Technology Data Exchange (ETDEWEB)

    Caird, J A; Agrawal, V; Bayramian, A; Beach, R; Britten, J; Chen, D; Cross, R; Ebbers, C; Erlandson, A; Feit, M; Freitas, B; Ghosh, C; Haefner, C; Homoelle, D; Ladran, T; Latkowski, J; Molander, W; Murray, J; Rubenchik, S; Schaffers, K; Siders, C W; Stappaerts, E; Sutton, S; Telford, S; Trenholme, J; Barty, C J

    2008-10-28

    We have developed preliminary conceptual laser system designs for the Laser ICF (Inertial Confinement Fusion) Fission Energy (LIFE) application. Our approach leverages experience in high-energy Nd:glass laser technology developed for the National Ignition Facility (NIF), along with high-energy-class diode-pumped solid-state laser (HEC-DPSSL) technology developed for the DOE's High Average Power Laser (HAPL) Program and embodied in LLNL's Mercury laser system. We present laser system designs suitable for both indirect-drive, hot spot ignition and indirect-drive, fast ignition targets. Main amplifiers for both systems use laser-diode-pumped Nd:glass slabs oriented at Brewster's angle, as in NIF, but the slabs are much thinner to allow for cooling by high-velocity helium gas as in the Mercury laser system. We also describe a plan to mass-produce pump-diode lasers to bring diode costs down to the order of $0.01 per Watt of peak output power, as needed to make the LIFE application economically attractive.

  11. Inference of ICF implosion core mix using experimental data and theoretical mix modeling

    Energy Technology Data Exchange (ETDEWEB)

    Sherrill, Leslie Welser [Los Alamos National Laboratory; Haynes, Donald A [Los Alamos National Laboratory; Cooley, James H [Los Alamos National Laboratory; Sherrill, Manolo E [Los Alamos National Laboratory; Mancini, Roberto C [UNR; Tommasini, Riccardo [LLNL; Golovkin, Igor E [PRISM COMP. SCIENCES; Haan, Steven W [LLNL

    2009-01-01

    The mixing between fuel and shell materials in Inertial Confinement Fusion (lCF) implosion cores is a current topic of interest. The goal of this work was to design direct-drive ICF experiments which have varying levels of mix, and subsequently to extract information on mixing directly from the experimental data using spectroscopic techniques. The experimental design was accomplished using hydrodynamic simulations in conjunction with Haan's saturation model, which was used to predict the mix levels of candidate experimental configurations. These theoretical predictions were then compared to the mixing information which was extracted from the experimental data, and it was found that Haan's mix model predicted trends in the width of the mix layer as a function of initial shell thickness. These results contribute to an assessment of the range of validity and predictive capability of the Haan saturation model, as well as increasing confidence in the methods used to extract mixing information from experimental data.

  12. Laser glass process development for the next generation of ICF lasers

    Science.gov (United States)

    Thorne, Alfred J.; Hayden, Joseph S.

    1997-12-01

    The next generation of high energy laser systems for ICF research demands an unprecedented volume of laser glass to be produced over a limited manufacturing period while still meeting ambitious targets of internal quality and overall cost. To meet this challenge, Schott has conceived a continuous manufacturing unit capable of producing 5,000 meter class PH 4 slabs of platinum particle-free phosphate laser glass within a three-year time period. This manufacturing unit concept draws on years of prior production experience with phosphate laser glass and other high quality optical materials but still represents a significant departure from the proven discontinuous manufacturing technology successfully employed over the last ten years for platinum-free phosphate laser glass. In addition, Schott has developed a new phosphate laser glass that simultaneously offers improvements in properties that relate to both laser performance and to characteristics related to forming the glass into large, high quality slabs. In this paper we will describe the key technology issues addressed in the manufacturing development and present a brief description of the planned manufacturing method to be employed. Lastly, the status of the development will be reviewed including characterization of pilot production melts of the new laser glass and the schedule for completion of the development program.

  13. Demonstration of Capability of Medium-Mass Pulsed Ion Beam as a Candidate for ICF Driver

    Science.gov (United States)

    Kasuya, Koichi; Kishi, Yohsuke; Kamiya, Takahiro; Saitoh, Satokazu; Funatsu, Masato; Renk, Tim; Turman, Bob; Leeper, Ramon; Mehlhorn, Thomas; Quintenz, Jeffrey

    1999-11-01

    Very small angle of beam source divergence was measured with a one-dimensional arrayed pin hole camera with 5 pin holes. Nitrogen beam including Oxygen beam was extracted from a cryogenic diode from N2O ice on the anode surface. Although we used a very rough apparatus (and it was not so sophisticated as the modern version), the absolute value of the divergence angle was 5-6 mrad. This value was enough small for us to recommend the beam as one of the candidates for the future ICF driver. The nominal diode voltage was 300-400 kV, and the peak ion current was 240 A. With the same apparatus, we observed rather large angle of 25-60 mrad for the proton beam in our former experiment. These results demonstrated that this kind of medium-mass ion beam must be investigated in more details to make clear the potential of the beam. We also used a Thomson parabola ion spectrometer to check the beam energy and the species. We could distinguish the different charge states of (singly and doubly ionized) Nitrogen and Oxygen, while the spatial resolution of the spectrometer was not enough high to distinguish the both species in the same charge states.

  14. Inertial confinement fusion. ICF quarterly report, October 1993--December 1993, Volume 4, Number 1

    Energy Technology Data Exchange (ETDEWEB)

    Powell, H.T.; Schleich, D.P.; Murphy, P.W. [eds.

    1994-05-01

    In the 1990 National Academy of Sciences (NAS) report of its review of the U.S. Inertial Confinement Fusion (ICF) Program, it was recommended that a high priority be placed on completing the Precision Nova Project and its associated experimental campaign. Since fiscal year 1990, the lab has therefore campaigned vigorously on Nova and in its supporting laboratories to develop the Precision Nova capabilities needed to perform the stressful target experiments recommended in the 1990 NAS report. The activities to enable these experiments have been directed at improvements in three areas - the Nova laser, target fabrication capabilities, and target diagnostics. As summarized in the five articles in this report, the Precision Nova improvements have been successfully completed. These improvements have had a positive impact on target performance and on the ability to diagnose the results, as evidenced by the HEP-1 experimental results. The five articles generally concentrate on improvements to the capabilities rather than on the associated target physics experiments. Separate abstracts are included for each paper.

  15. Surrogate models for identifying robust, high yield regions of parameter space for ICF implosion simulations

    Science.gov (United States)

    Humbird, Kelli; Peterson, J. Luc; Brandon, Scott; Field, John; Nora, Ryan; Spears, Brian

    2016-10-01

    Next-generation supercomputer architecture and in-transit data analysis have been used to create a large collection of 2-D ICF capsule implosion simulations. The database includes metrics for approximately 60,000 implosions, with x-ray images and detailed physics parameters available for over 20,000 simulations. To map and explore this large database, surrogate models for numerous quantities of interest are built using supervised machine learning algorithms. Response surfaces constructed using the predictive capabilities of the surrogates allow for continuous exploration of parameter space without requiring additional simulations. High performing regions of the input space are identified to guide the design of future experiments. In particular, a model for the yield built using a random forest regression algorithm has a cross validation score of 94.3% and is consistently conservative for high yield predictions. The model is used to search for robust volumes of parameter space where high yields are expected, even given variations in other input parameters. Surrogates for additional quantities of interest relevant to ignition are used to further characterize the high yield regions. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344, Lawrence Livermore National Security, LLC. LLNL-ABS-697277.

  16. X-ray spectroscopic signatures of ion species separation in ICF implosions on OMEGA

    Science.gov (United States)

    Hakel, Peter; Hsu, Scott; Herrmann, Hans; Kim, Yong Ho; Schmitt, Mark; Kagan, Grigory; McEvoy, Aaron; Colgan, James; Fontes, Christopher; Kilcrease, David; Sherrill, Manolo; Rauenzahn, Rick

    2015-11-01

    This work aims to provide a direct measurement of the species separation through experimental inference of the ion density profiles, and comparisons of the data with simulations that explicitly model multi-ion-species diffusion. We also describe the development of a new code capable of modeling x-ray spectral emission from ICF capsules that accounts for the effects of spatial gradients in species distributions throughout the target. This new code named FESTR also allows the inclusion of NLTE, opacity, and Stark broadening effects on x-ray spectral line emissions. We show preliminary results from an OMEGA campaign to obtain direct measurements of ion species separation via advanced analysis of x-ray spectroscopy and spectrally resolved imaging data. These were symmetric direct-drive implosions of CH capsules with deuterium and trace argon gas fills. The implosions were designed to be in a collisional, diffusive regime and to take advantage of interspecies diffusion between the D and Ar driven by temperature gradients in the hot spot. X-ray spectral line emissions and narrowband images from He-like and H-like Ar ions are used to infer the spatial separation of Ar from D.

  17. PRP Comments for ICF Q1/Q2 FY17 Experiments 3/10/16

    Energy Technology Data Exchange (ETDEWEB)

    Kauffman, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-04-14

    The PRP generally endorsed the Program plan during the short time for discussions. We agree that the strategy to develop a hohlraum that is symmetric and has low laser-plasma instabilities and to develop an alternative method for supporting the capsule is the best path forward for making progress in understanding ignition performance. The Program is oriented toward a milestone in 2020 for “determining the efficacy of NIF for ignition and credible physics-scaling to multi-megajoule yields for all ICF approaches.” We are concerned that the time and resources are not sufficient to vet all of the various approaches that are being pursued to make an informed decision by this date. For NIF to meet this goal, a process will be needed to to select the most promising paths forward. We recommend that the Program develop this process for selecting the path forward to optimize resources. We were glad to see that the direct drive program took our comments under consideration. We think that the proposed experiments have the program headed in a better direction. The PRP had only a short time to discuss the detailed experimental proposals. The following are comments on the detailed proposals. We did not have time to discuss them as a group. They represent individual opinions and provided to you as feedback to your proposals.

  18. Hydrodynamic instability measurements in DT-layered ICF capsules using the layered-HGR platform

    Science.gov (United States)

    Weber, C.; Döppner, T.; Casey, D.; Bunn, T.; Carlson, L.; Dylla-Spears, R.; Kozioziemski, B.; MacPhee, A. G.; Sater, J.; Nikroo, A.; Robey, H.; Smalyuk, V.

    2016-05-01

    The first measurements of hydrodynamic instability growth at the fuel-ablator interface in an ICF implosion are reported. Previous instability measurements on the National Ignition Facility have used plastic capsules to measure ablation front Rayleigh-Taylor growth with the Hydro.-Growth Radiography (HGR) platform. These capsules substituted an additional thickness of plastic ablator material in place of the cryogenic layer of Deuterium- Tritium (DT) fuel. The present experiments are the first to include a DT ice layer, which enables measurements of the instability growth occurring at the fuel-ablator interface. Instability growth at the fuel-ablator interface is seeded differently in two independent NIF experiments. In the first case, a perturbation on the outside of the capsule feeds through and grows on the interface. Comparisons to an implosion without a fuel layer produce a measure of the fuel's modulation. In the second case, a modulation was directly machined on the inner ablator before the fuel layer was added. The measurement of growth in these two scenarios are compared to 2D rad-hydro modeling.

  19. ICStatus and progress of the National Ignition Facility as ICF and HED user facility

    Science.gov (United States)

    Van Wonterghem, B. M.; Kauffman, R. L.; Larson, D. W.; Herrmann, M. C.

    2016-05-01

    Since its completion in 2009, the National Ignition Facility has been operated in support of NNSA's Stockpile Stewardship mission, providing unique experimental data in the high energy density regime. We will describe the progress made by the National Ignition facility in the user office and management, facility capabilities, target diagnostics and diagnostics development. We will also discuss the results of a major effort to increase the shot rate on NIF. An extensive set of projects, developed in conjunction with the HED community and drawing on best practices at other facilities, improved shot rate by over 80% and recently enabled us to deliver 356 target experiments in FY15 in support of the users. Through an updated experimental set-up and review process, computer controlled set-up of the laser and diagnostics and disciplined operations, NIF also continued to deliver experimental reliability, precision and repeatability. New and complex platforms are introduced with a high success rate. Finally we discuss how new capabilities and further efficiency improvements will enable the successful execution of ICF and HED experimental programs required to support the quest for Ignition and the broader Science Based Stockpile Stewardship mission

  20. Scattered and (n,2n) neutrons as a measure of areal density in ICF capsules

    CERN Document Server

    Wilson, D C; Disdier, L; Houry, M; Bourgade, J L; Murphy, T J

    2002-01-01

    The fraction of low-energy neutrons created from 14 MeV neutrons by elastic scattering and (n,2n) reactions on D and T has been proposed as a measure of the areal density (radial integral of density) of ICF targets. In simple situations the fraction of neutrons between 9.4 (the upper energy of T+T neutrons) and 13 MeV (below the Doppler broadened 14.1 MeV peak) is proportional to the at the time of neutron production. This ratio does not depend upon the temperature of the fuel, as does the number of reaction-in-flight neutrons. The ratio of neutrons elastically scattered at a specific energy (e.g. 13 MeV) to the total number of neutrons can be measured along different lines of sight. The ratio of two perpendicular measurements provides a quantitative measure of asymmetry. A detector can be placed inside the target chamber to measure these low-energy neutrons. If it is close enough to the target that measurements are made before the 14 MeV neutrons reach the chamber wall, gamma rays can be a negligible back...

  1. SRS analyses of direct-drive ICF experiments at the National Ignition Facility

    Science.gov (United States)

    Michel, P.; Rosenberg, M.; Myatt, J.; Solodov, A.; Seka, W.; Chapman, T.; Hohenberger, M.; Masse, L.; Goyon, C.; Turnbull, D.; Regan, S.; Moody, J. D.

    2016-10-01

    A series of planar target experiments was recently conducted at the National Ignition Facility (NIF) to study the laser-plasma interactions processes responsible for the production of suprathermal electrons, and their scaling from experiments at the Omega facility to full-scale ICF experiments at the MJ level on the NIF. We will present experimental analyses and simulations of Stimulated Raman Scattering (SRS) in these planar target experiments. Our work indicates the presence of purely backscattered SRS refracted off nearly one-dimensional density gradients, as well as more complicated features such as side-scatter and scattering from non-1D features (e.g. edges) in the target. Simulations using ray- and paraxial-wave- based simulation codes are used to extrapolate the hot electron fraction from the SRS measurements, and point to SRS being the primary mechanism for the generation of suprathermal electrons in these experiments. We will also present analyses of spherical implosions experiments and provide extrapolations and implications for future full-scale direct-drive experiments at NIF. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  2. Discrepancies in how the impact of gout is assessed in outcomes research compared to how health professionals view the impact of gout, using the lens of the International Classification of Functioning, Health and Disability (ICF).

    Science.gov (United States)

    Kool, Eveline M; Nijsten, Marieke J; van Ede, Annelies E; Jansen, Tim L; Taylor, William J

    2016-09-01

    The International Classification of Functioning, Disability and Health (ICF) provides a common language to understand what health means. An ICF core set, a list of ICF categories affected by a certain disease, is useful to objectify the content validity of a health status measurement. This study aims to identify the potential items of a gout specific 'ICF core set'. A three-round Delphi exercise was conducted, using web-based questionnaires. Health professionals, specialized in gout, nominated and subsequently rated the relevance of life areas divided into ICF categories. Agreement was determined by using the UCLA/RAND criteria. Simultaneously, a systematic review of gout measure outcomes was conducted. The results of these studies were compared using the second level of the ICF categories. In the Delphi study, consensus was found for 136 relevant ICF categories. The literature study extracted 134 different ICF categories in 149 articles. Three hundred and ten were non-defined outcomes. A large number of ICF categories were deemed to be relevant for people with gout. Only 29.7 % (19/64) of the level 2 categories, deemed to be relevant by health professionals, had been assessed as relevant in at least 5 % of gout outcome studies. Conversely, 70 % (19/27) of level 2 ICF categories assessed in at least 5 % of outcome studies were deemed relevant by health professionals. These ICF codes, which are found relevant in both studies, should be considered as mandatory in further research to a validated and practical core set of ICF categories. Published gout outcomes research fails to evaluate many life areas that are thought relevant by health professionals.

  3. Capa catalítica para la activación de oxígeno sobre electrolitos sólidos iónicos a alta temperatura

    OpenAIRE

    Serra Alfaro, José Manuel; Vert Belenguer, Vicente Bernard; Escolástico Rozalén, Sonia

    2008-01-01

    Capa catalítica para la activación de oxígeno sobre electrolitos sólidos iónicos a alta temperatura. La presente invención se refiere a una capa porosa catalítica para la activación de oxígeno que puede ser utilizada en pilas de combustible de óxidos sólidos (SOFC) y en membranas cerámicas densas de separación de oxígeno de alta temperatura. Esta capa porosa está formada principalmente por un material conductor mixto de electrones y del ión oxígeno y posee una estructu...

  4. The "Comprehensive ICF Core Set for Head and Neck Cancer": a Delphi consensus survey among German speaking speech and language therapists.

    Science.gov (United States)

    Engelbarts, Matthias; Schuster, Vanessa; Kisser, Ulrich; Sabariego, Carla; Stier-Jarmer, Marita; Coenen, Michaela; Ernst, Benjamin Philipp; Strieth, Sebastian; Harréus, Ulrich; Becker, Sven

    2017-02-24

    The "Comprehensive ICF Core Set for Head and Neck Cancer" (ICF-HNC) is an application of the "International Classification of Functioning, Disability and Health" (ICF), representing the characteristic spectrum of issues in patients with head and neck cancer (HNC). Our primary aim was to evaluate which categories of the ICF-HNC are dealt with by speech and language therapists (SLTs) in Germany, Austria, and Switzerland. The secondary aim was to identify outcome measures used by SLTs to measure the categories of the ICF-HNC in clinical practice. SLTs experienced in the treatment of HNC patients evaluated the categories of the ICF-HNC in a three-round Delphi survey. They were asked whether the listed categories represented issues treated by SLTs in HNC patients, and what outcome measures were used to assess them. Altogether, 31 SLTs completed the survey. 47 of 108 previously selected categories of the ICF-HNC achieved the cut-off value. Out of these, 40.4% were derived from the component "Body Functions", 36.2% from "Body Structures", 12.8% from "Environmental Factors", and 10.6% from "Activities and Participation". Altogether, 82 of the mentioned outcome measures were considered as reasonable from the perspective of SLTs. Of these, only 37 achieved more than 50% approval. This study emphasises the importance of "Body Structures" and "Body Functions" for SLTs in Germany and Switzerland in treating patients with HNC. Moreover, the results highlighted the need to agree on evidence-based outcome measures in speech and language therapy.

  5. Implante subcutáneo de un carcinoma hepatocelular tras la punción aspiración con aguja fina Subcutaneous seeding of hepatocellular carcinoma after fine-needle percutaneous biopsy

    Directory of Open Access Journals (Sweden)

    D. Martínez Ramos

    2007-06-01

    Full Text Available Los implantes subcutáneos son una complicación rara tras la punción aspiración con aguja fina de los carcinomas hepatocelulares. Los autores describen un caso de implante subcutáneo neoplásico en una mujer de 70 años con cirrosis hepática por virus C complicada con un carcinoma hepatocelular. Se efectuó una punción aspiración con aguja fina en el segmento II hepático. El implante tumoral se desarrolló en el trayecto de la punción aspiración. La tumoración subcutánea fue extirpada quirúrgicamente y el estudio anatomopatológico confirmó que se trataba de un carcinoma hepatocelular bien diferenciado.Subcutaneous tumor seeding after fine-needle percutaneous biopsy for hepatocellular carcinoma is a rarely seen complication. The authors describe a case of subcutaneous neoplastic seeding in a 70-year-old woman with chronic hepatitis C virus complicated by hepatocellular carcinoma. Ultrasonically guided fine-needle aspiration biopsy was performed in segment II of the liver. The neoplastic seeding developed along the needle track used to carry out the fine-needle biopsy. The subcutaneous tumor was excised, and histological examination revealed a well-differentiated hepatocellular carcinoma.

  6. Avaliação da motricidade ampla e fina na Síndrome de Williams: relato de caso Findings of the gross and fine motor in the Syndrome William Case: case Report

    Directory of Open Access Journals (Sweden)

    Marcela Melo Almeida

    2010-12-01

    Full Text Available O presente estudo teve como objetivo analisar os achados da motricidade ampla e fina de uma criança de 8 anos de idade portador da Síndrome de Williams. Foram coletados dados biológicos da criança e da mãe durante a gestação e história pré, peri e pós-natal da criança e suas condições clínicas. O desenvolvimento motor amplo e fino foi avaliado pelo Inventário Portage Operacionalizado. Os resultados demonstraram que a criança revelou maior dificuldade na motricidade fina em relação à ampla, apresentando dificuldades na escrita, em manipular objetos que necessite fazer movimento de pronação e supinação e dificuldade no movimento de pinça.This study aimed to analyze the findings of motor and fine of an 8 years old holder of Williams Syndrome. Data were collected biological child and mother during pregnancy and history of pre, peri and postnatal child and their clinical conditions. The development and fine motor function was assessed by Portage Guide. The results showed that children showed greater difficulty with fine motor skills in relation to gross skills, having difficulty in writing, to manipulate objects that need to make movement of pronation and supination and difficulty in of the pincer movement.

  7. Caracterización metalográfica de capas cromadas por difusión // Metallographic characterization of diffusion chromized layers

    Directory of Open Access Journals (Sweden)

    J. E. González Ruiz

    1999-01-01

    Full Text Available En el trabajo se aborda la aplicación de procesos de cromado difusivo obtenidos a partir de mineral de cromo refractariomediante el método metalotérmico. En primer término se realiza una caracterización metalográfica de las capas cromadas pordifusión y sus zonas adyacentes en aceros AISI 1015, 1045, 1055 y W108, de forma adicional se estudia un hierro fundido conuna matriz predominantemente perlítica y un contenido de carbono de 3%.También es tratado el efecto ejercido por el contenido de carbono presente en los materiales anteriormente mencionados sobreel espesor de las capas y en los valores de microdureza alcanzados en la sección transversal de éstas, haciendo énfasis en lazona compuesta por carburos complejos de cromo - hierro.\\Palabras claves: Cromado di fusivo, di fusión, recubrimiento, deposición, cromi ta._______________________________________________________________________AbstractIn this work, a valorization of the influence of base metal carbon contents in the morphology, microhardness and depth of thechromium diffusive layers, obtained from Cuban refractory chromites was realized. For this purpose a low – carbon – steel1015 ( AISI , two medium carbon steel contents 1045 and 1055 ( AISI and a high carbon steel contents W 108 ( AISI .Furthermore, a cast iron with a perlitic matrix was selected.Key words: Di f fusion chromized, deposi t ion, chromi t es, layer.

  8. Evaluación del espesor de capas delgadas mediante análisis EDS y simulación de Monte Carlo

    Directory of Open Access Journals (Sweden)

    García, J. C.

    2010-12-01

    Full Text Available This work shows a method to evaluate the thin layer thickness by the X ray dispersive energy (EDS technique. The analytical measures of the area of characteristic peaks carried out with this technique are complemented with electron trajectories on the interaction volume byMonte Carlo simulation. These together with the estimations obtained for the characteristic peaks intensities according to Bethe, Joy&Luo algorithm makes possible to estimate the thickness of samples.En este trabajo se presenta un método de evaluación de espesores de capas delgadas mediante la técnica de energías dispersivas de rayos X (EDS. Las medidas analíticas de las áreas de los picos característicos de los elementos detectados en las capas, obtenidas mediante esta técnica, se complementan con simulaciones de Monte Carlo de las trayectorias de los electrones en el volumen de interacción. Esto, junto con las estimaciones de la intensidad de los picos característicos obtenidos mediante el algoritmo de Bethe, Joy & Luo, posibilita realizar la estimación de los espesores de las muestras analizadas.

  9. Irradiación subletal de fibroblastos murinos 3T3 con rayos X para su utilización como capa celular alimentadora

    Directory of Open Access Journals (Sweden)

    Andrea Ramírez-Téllez

    2015-05-01

    Full Text Available Los queratinocitos, las principales células de la epidermis, requieren una capa alimentadora de células viables mitóticamente inactivadas para su supervivencia y proliferación in vitro. Para la producción de capas alimentadoras a partir de fibroblastos murinos 3T3, se evaluaron cuatro dosis de radiación con rayos X. Los efectos de las dosis se evaluaron mediante recuentos celulares y determinación de la viabilidad (MTT, adhesión (eficiencia de plateo y migración celular (scratch wound healing. Además, se encontraron evidencias que sugieren el arresto mitótico mediante una tinción nuclear (GIEMSA. Se observó que una dosis de radiación correspondiente a 80 Gy generó daños suficientes en la línea celular para causar el arresto mitótico, manteniendo a la vez la actividad metabólica basal durante 25 días.

  10. Análisis comparativo de métricas de QoS de Redes Wi-Fi 802.11e con capa física 802.11n y 802.11ac

    OpenAIRE

    Pérez, Santiago; Mercado, Gustavo; Facchini, Higinio Alberto; Dantiacq, Alejandro; Cangemi, Gastón; Quiroga Salomón, Gabriel

    2016-01-01

    Las Redes Inalámbricas basadas en IEEE 802.11 se han vuelto las redes más populares en el acceso a los servicios WLAN corporativos y de banda ancha móvil/wireless de Internet. Para satisfacer los requerimientos de QoS (Quality of Service - Calidad de Servicio) se introdujo, a nivel de Capa 2, la tecnología IEEE EDCA (Enhanced Distributed Channel Access) 802.11e. Mientras que para satisfacer mayores velocidades de transferencias, a nivel de Capa 1, se han sucedido diversas mejoras introduci...

  11. Capas de a-SiN:H modificadas mediante la irradiación con un láser de excímero

    Directory of Open Access Journals (Sweden)

    Banerji, N.

    1998-04-01

    Full Text Available Hydrogenated amorphous silicon nitride (a:SiN:H films produced by CO2 and ArF laser-induced CVD in parallel configuration using silane/ammonia or disilane/ammonia gas mixtures were subjected to room temperature multiple pulse ArF excimer laser irradiations in an inert gas atmosphere. Modifications in their chemical composition, refractive index, and surface morphology were systematically followed up through Fourier-transform infrared spectroscopy (FTIR, energy dispersive X-ray spectroscopy (EDS, single wavelength ellipsometry and atomic force microscopy (AFM, respectively. The observed film modifications involving large reductions in hydrogen (Si-H and N-H with the first few shots accompanied by a progressive incorporation of oxygen (Si-O and Si-OH and a reduction of Si-N bonds that are attributed to UV-induced photochemistry where the atmospheric water incorporated in the films between successive irradiations plays an important role. Comparison among the different films indicated that the extent of bonded hydrogen in the films and their surface morphology influence their oxidation resistance.

    Utilizando una mezcla de silano/amoníaco o disilano/amoníaco se obtuvieron capas de nitruro de silicio amorfo hidrogenado (a-SiN:H mediante depósito químico en fase vapor asistido por láser CO2 y ArF, ambos en configuración paralela. Estas capas se sometieron a irradiación con un láser excímero de ArF en atmósfera inerte. Las variaciones, tanto en su composición química como en su índice de refracción y morfología superficial se estudiaron sistemáticamente mediante espectroscopia infrarroja por transformada de Fourier (FTIR, espectroscopia dispersiva de rayos X (EDS, elipsometría y microscopía de fuerzas atómicas (AFM, respectivamente. Las modificaciones observadas involucran por una parte una gran reducción, con los primeros pulsos de irradiación, del hidrógeno enlazado (Sili y N-H, acompañado por una

  12. MASA TOTAL Y CONTENIDO DE NUTRIENTES EN RAÍCES FINAS DE ECOSISTEMAS FORESTALES (Pinus patula Schltdl y Cham Cupressus lusitanica Mill y Quercus humboldtii Bonpl.) DE PIEDRAS BLANCAS, ANTIOQUIA-COLOMBIA TOTAL FINE ROOT MASS AND NUTRIENT CONTENT IN FOREST ECOSYSTEMS (Pinus patula Schltdl and Cham Cupressus lusitanica Mill and Quercus humboldtii Bonpl.) FROM PIEDRAS BLANCAS, ANTIOQUIA-COLOMBIA

    OpenAIRE

    2005-01-01

    En la región de Piedras Blancas, Antioquia - Colombia, se realizó un muestreo de raíces finas (£ 5 mm) en tres parcelas permanentes establecidas en bosques de pino pátula (Pinus patula Schltdl y Cham), ciprés (Cupressus lusitanica Mill) y roble (Quercus humboldtii Bonpl.) a diferentes profundidades: 0-30, 30-50 y 50- 80 cm, con el fin de determinar la masa de raíces, y la concentración y contenido de nutrientes en cada cobertura vegetal. La masa de raíces finas disminuyó rápidamente a medida ...

  13. Linking self-determined functional problems of patients with neck pain to the International Classification of Functioning, Disability, and Health (ICF

    Directory of Open Access Journals (Sweden)

    Andelic N

    2012-10-01

    Full Text Available Nada Andelic,1 Jan Borre Johansen,1 Erik Bautz-Holter,1,2 Anne Marit Mengshoel,3 Eva Bakke,3 Cecilie Roe1,21Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Oslo, Norway; 2Faculty of Medicine, University of Oslo, Oslo, Norway; 3Department of Health Sciences, Institute of Health and Society, University of Oslo, Oslo, NorwayObjective: To describe commonly reported self-determined functional problems in patients with neck pain and to evaluate their fit to the components of the International Classification of Functioning, Disability, and Health (ICF.Methods: Overall, 249 patients were included in this cross-sectional study that comprised patients with neck pain referred to the outpatient clinic at Oslo University Hospital (2007–2009. Patients were asked to report their three most significant functional problems on the Patient-Specific Functional Scale, a self-determined measure of function. The ICF was used as a tool for analysis. Meaningful concepts within the functional problems were identified, coded, and linked to second-level categories within the components of “body functions,” and “activities and participation.” Two researchers performed coding and linking independently. The ICF categories were presented by percentage of the total number of functional problems linked to the ICF.Results: Of 628 reported functional problems, 13 meaningful ICF domains were identified: four domains belonging to the body functions component (b and nine domains belonging to activities and participation components (d. Within the 88 second-level ICF classification categories of body functions, the most frequently reported items were sleep function (b134; 27% and mobility of joint functions (b710; 26%. Within the 538 second-level categories of activities and participation, remunerative employment was reported as the most frequent item (d850; 15%, closely followed by doing housework (d640; 14%, and recreation and leisure

  14. Characterizing ICF Neutron Scintillation Diagnostics on the nTOF line at SUNY Geneseo

    Science.gov (United States)

    Lawson-Keister, Pat; Padawar-Curry, Jonah; Visca, Hannah; Fletcher, Kurt; Padalino, Stephen; Sangster, T. Craig; Regan, Sean

    2015-11-01

    Neutron scintillator diagnostics for ICF and HEDP can be characterized using the neutron time-of-flight (nTOF) line on Geneseo's 1.7 MV tandem Pelletron accelerator. Neutron signals can be differentiated from gamma signals by employing coincidence methods. A 1.8-MeV beam of deuterons incident on a deuterated polyethylene target produces neutrons via the 2H(d,n)3He reaction. Neutrons emerging at a lab angle of 88° have an energy of 2.96 MeV; the 3He ions associated with these neutrons are detected at a scattering angle of 43° using a surface barrier detector. The time of flight of the neutron can be measured by using the 3He detection as a ``start'' signal and the scintillation detection as a ``stop'' signal. This time of flight requirement is used to identify the 2.96-MeV neutron signals in the scintillator. To measure the light curve produced by these monoenergetic neutrons, two photomultiplier (PMT) tubes are attached to the scintillator. The full aperture PMT establishes the nTOF coincidence. The other PMT is fitted with a pinhole to collect single events. The time between the full aperture PMT signal and the arrival of the signal in the pinhole PMT is used to determine the light curve for the scintillator. This system will enable the neutron response of various scintillators to be compared. Supported in part by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

  15. A pilot to investigate the use of the icf in documenting levels of function and disability in people living with hiv

    Directory of Open Access Journals (Sweden)

    J. Jelsma

    2006-02-01

    Full Text Available Objective: The study was a pilot study aimed at investigating the use of the International Classification of Functioning, Disability and Health (ICF checklist developed by the World Health Organisation in determining the function of individuals living with HIV in a township near Cape Town.Methods: Twelve participants attending the HIV clinic were examinedusing the ICF checklist.Findings: Areas of the ICF in which problems were noted included emotional functioning and energy and drive. Four participants complained of increased sensitivity to sound. Several respondents (three reported difficulties in relationships with community members, with less having problems in family and intimate relationships. Conclusion: The ICFwas found to be time consuming and many codes were not relevant. Some of the concepts were not well understood by the participants. However, despite limitations, the use of the ICF in a resource poor setting formed a useful framework within which to examine the functional problems of HIV infected individuals. In the absence of any equivalent unifying framework within which to classify health and health related states, the use of the ICF merits further investigation.

  16. POTENCIAL DE REGENERACIÓN DE Psychotria ipecacuanha (Rubiaceae A PARTIR DE CAPAS DELGADAS DE CÉLULAS

    Directory of Open Access Journals (Sweden)

    Catalina BOTERO GIRALDO

    2015-07-01

    Full Text Available Conociendo las propiedades medicinales de la especie vegetal Psychotria ipecacuanha (Brot. Stokes, su crítico estado de conservación, así como las dificultades que presenta para la propagación efectiva, el presente estudio tuvo como objetivo evaluar su potencial de propagación por los sistemas de regeneración in vitro, organogénesis y embriogénesis somática. Para este propósito, capas delgadas de células (CDCs de tallos y de hojas, así como segmentos foliares fueron sometidos a diferentes tratamientos con reguladores de crecimiento y condiciones de luz. Además se estableció el efecto de diferentes longitudes de onda vía diodos emisores de luz (LEDs, sobre la regeneración en estos explantes y nudos provenientes de plantas in vitro. Los resultados obtenidos mostraron que los segmentos de hoja y las CDCs de tallo sembrados en el medio de cultivo MS suplementado con las combinaciones de los reguladores de crecimiento IBA + BAP e IBA + TDZ formaron embriones somáticos y brotes. Los cortes histológicos realizados corroboraron estos dos tipos de origen. Se encontró que bajo la condición lumínica 16/8, se alcanzaron los mejores resultados de inducción de brotes y embriones. En cuanto al efecto de las diferentes longitudes de onda de luz, se encontró que las correspondientes al rojo, verde y blanca, favorecieron el crecimiento y desarrollo de brotes y la inducción de embriones somáticos. El desarrollo de los brotes a partir de los nudos no presentó diferencias estadísticas entre los tratamientos con LEDs, por lo que se recomienda el uso de la luz blanca continua y con fotoperiodo durante el proceso de multiplicación y desarrollo de estos.Regeneration Potential of Psychotria Ipecacuanha (Rubiaceae from Thin Cell Layers Knowing the medicinal properties of the plant specie Psychotria ipecacuanha (Brot. Stokes, its critical condition and the difficulties for its effective propagation, the present study aimed to assess the

  17. ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing.

    Science.gov (United States)

    Gatto, Sole; Gagliardi, Miriam; Franzese, Monica; Leppert, Sylwia; Papa, Mariarosaria; Cammisa, Marco; Grillo, Giacomo; Velasco, Guillame; Francastel, Claire; Toubiana, Shir; D'Esposito, Maurizio; Angelini, Claudia; Matarazzo, Maria R

    2017-03-09

    Hypomorphic mutations in DNA-methyltransferase DNMT3B cause majority of the rare disorder Immunodeficiency, Centromere instability and Facial anomalies syndrome cases (ICF1). By unspecified mechanisms, mutant-DNMT3B interferes with lymphoid-specific pathways resulting in immune response defects. Interestingly, recent findings report that DNMT3B shapes intragenic CpG-methylation of highly-transcribed genes. However, how the DNMT3B-dependent epigenetic network modulates transcription and whether ICF1-specific mutations impair this process remains unknown. We performed a transcriptomic and epigenomic study in patient-derived B-cell lines to investigate the genome-scale effects of DNMT3B dysfunction. We highlighted that altered intragenic CpG-methylation impairs multiple aspects of transcriptional regulation, like alternative TSS usage, antisense transcription and exon splicing. These defects preferentially associate with changes of intragenic H3K4me3 and at lesser extent of H3K27me3 and H3K36me3. In addition, we highlighted a novel DNMT3B activity in modulating the self-regulatory circuit of sense-antisense pairs and the exon skipping during alternative splicing, through interacting with RNA molecules. Strikingly, altered transcription affects disease relevant genes, as for instance the memory-B cell marker CD27 and PTPRC genes, providing us with biological insights into the ICF1-syndrome pathogenesis. Our genome-scale approach sheds light on the mechanisms still poorly understood of the intragenic function of DNMT3B and DNA methylation in gene expression regulation.

  18. White Paper on Ion Beam Transport for ICF: Issues, R&D Need,and Tri-Lab Plans

    Energy Technology Data Exchange (ETDEWEB)

    Olson, C.; Lee, E.; Langdon, B.

    2005-05-04

    To date, most resources for ion beam fusion have been devoted to development of accelerators and target physics; relatively few resources have gone into ion beam transport development. Because of theoretical studies and substantial experience with electron beam transport, the ion beam transport community is now poised to develop and optimize ion beam transport for ICF. Because of this Tri-Lab effort, a path for coordinated development of ion beam transport has been established. The rate of progress along this path will now be determined largely by the availability of resources.

  19. Efectos de las capas someras de alta velocidad en los datos sísmicos aplicados a la detección de hidrocarburos

    Directory of Open Access Journals (Sweden)

    Guevara Saul

    2003-08-01

    Full Text Available

    Elastic waves provide characteristics of earth interior, which are necessary in Hydrocarbon and mineral prospect ions. This information is affected by shallow layers distorting the data coming from deep layers. In the colombian geology are fragment shallow layer with high velocity. In this case waves travel by anomalous paths being difficult to identity them, because these events contaminate and alternate the information considerated usefull. The effects associated to this phenomena are unknown with details. In this paper, one of these case is presented througen seismic modeling and vial data with an interpretation about its characteristics.

    Las ondas elásticas son una importante fuente de información de las  características del interior de la tierra, necesarios en la búsqueda de hidrocarburos y otros recursos minerales. Esta información es afectada generalmente por las capas someras, cuyas características distorsionan los datos provenientes de las capas de interés, usual mente más profundas. Un caso, frecuente en la geología colombiana es el de las capas someras de alta velocidad. En este caso las ondas siguen direcciones anómalas, y con frecuencia la información es muy difícil de identificar, ya que se generan eventos que la contaminan y probablemente la atenúan, Aunque se sabe que existe este efecto, muchos de sus detalles son desconocidos. Aquí se presenta uno de estos casos, se ilustra con modelamiento sísmico con datos reales y se presenta una interpretación de sus características.

  20. Cálculo del asiento elástico tridimensional de cimentaciones de rigidez variable en terrenos con una capa rígida inclinada

    Directory of Open Access Journals (Sweden)

    Díaz, E.

    2016-06-01

    Full Text Available The formulas based on the elasticity theory are widely used for the calculation of foundation settlements, as the geotechnical regulations recommends their use. However, these methods do not cover all possible geotechnical situations because, frequently, the geotechnical conditions are complex. In this work, the influence of an inclined rigid layer on the elastic settlements of a shallow foundation is analysed. For this purpose, 273 three-dimensional non-linear finite element models have been solved varying the key parameters of the problem: inclination and depth of the rigid layer and the rigidity of the foundation. Finally, a statistical analysis of the results of the models has been performed and a formula, which can be used for the calculation of the settlements to consider the presence of a rigid inclined layer in depth, has been proposed.Las fórmulas basadas en la teoría de la elasticidad son ampliamente utilizadas para el cálculo de asientos de cimentaciones, ya que la totalidad de la normativa geotécnica recomienda su empleo. No obstante, estos métodos no cubren todas las situaciones geotécnicamente posibles ya que frecuentemente las condiciones geológicas son complejas. En este trabajo se analiza la influencia de la presencia de una capa rígida inclinada en los asientos elásticos de una cimentación superficial. Para ello se han resuelto 273 modelos tridimensionales no lineales de elementos finitos, variando los parámetros clave del problema: la inclinación y la profundidad de la capa rígida y la rigidez de la cimentación. Finalmente, se ha realizado un análisis estadístico de los resultados de los modelos y se ha propuesto una fórmula que puede ser utilizada en el cálculo de asientos por métodos elásticos, para tener en consideración la presencia de una capa rígida inclinada en profundidad.

  1. Evolução temporal da explosão solar de 06 de junho de 2000 apresentando estruturas finas em rádio freqüências

    Science.gov (United States)

    Fernandes, F. C. R.; Sawant, H. S.; Cecatto, J. R.; Caracini, A. G.; Vats, H. O.; Karlický, M.; Meszarosova, H.

    2003-08-01

    Em 06 de junho de 2000 (~15: 00-17: 00 UT), o Brazilian Solar Spectroscope (BSS) registrou uma explosão solar intensa no intervalo de freqüência de (1000-2000) MHz, com alta resolução temporal (100 ms) e espectral (5 MHz). A atividade solar relacionada a esta explosão associada à região ativa (AR) 9026 e classificada como X2.3 foi grande. O Ondrejov Observatory registrou rádio emissões até 4,5 GHz. O satélite SOHO registrou uma série de erupções solares, incluindo uma Ejeção de Massa Coronal (CME) tipo "full-halo" (~15: 54 UT). Explosões tipo II/IV também foram registradas. Na faixa de ondas decimétricas, este evento apresentou dois picos distintos (~15: 21 UT e ~16: 42 UT). O primeiro pico coincide com a explosão registrada em raios-X moles (GOES) e em raios-X duros (Yohkoh). Os espectros dinâmicos com alta resolução do BSS revelaram várias estruturas finas, principalmente emissões tipo "zebra" e "fibra", rádio pulsações, emissões tipo III e do único caso de emissões "zebra" harmônicas observado na faixa decimétrica. Neste trabalho, analisamos a evolução temporal e o comportamento global do evento de 06 de junho de 2000, com ênfase na identificação e associação da ocorrência de cada tipo de estrutura fina registrada em rádio com cada etapa da explosão. Resultados preliminares mostraram que, na fase pré-flare, as estruturas finas apresentaram taxa de deriva negativa (~ 70-190 MHz/s). As emissões tipo "zebra" concentram-se na fase de descida do primeiro pico impulsivo e na de subida do segundo pico. Enquanto que as emissões tipo "fibra" ocorrem em ambas fases, mas preferivelmente durante a fase de descida. Os resultados serão apresentados e discutidos.

  2. Using the International Classification of Functioning, Disability and Health (ICF to describe children referred to special care or paediatric dental services.

    Directory of Open Access Journals (Sweden)

    Denise Faulks

    Full Text Available Children in dentistry are traditionally described in terms of medical diagnosis and prevalence of oral disease. This approach gives little information regarding a child's capacity to maintain oral health or regarding the social determinants of oral health. The biopsychosocial approach, embodied in the International Classification of Functioning, Disability and Health - Child and Youth version (ICF-CY (WHO, provides a wider picture of a child's real-life experience, but practical tools for the application of this model are lacking. This article describes the preliminary empirical study necessary for development of such a tool - an ICF-CY Core Set for Oral Health. An ICF-CY questionnaire was used to identify the medical, functional, social and environmental context of 218 children and adolescents referred to special care or paediatric dental services in France, Sweden, Argentina and Ireland (mean age 8 years ± 3.6 yrs. International Classification of Disease (ICD-10 diagnoses included disorders of the nervous system (26.1%, Down syndrome (22.0%, mental retardation (17.0%, autistic disorders (16.1%, and dental anxiety alone (11.0%. The most frequently impaired items in the ICF Body functions domain were 'Intellectual functions', 'High-level cognitive functions', and 'Attention functions'. In the Activities and Participation domain, participation restriction was frequently reported for 25 items including 'Handling stress', 'Caring for body parts', 'Looking after one's health' and 'Speaking'. In the Environment domain, facilitating items included 'Support of friends', 'Attitude of friends' and 'Support of immediate family'. One item was reported as an environmental barrier - 'Societal attitudes'. The ICF-CY can be used to highlight common profiles of functioning, activities, participation and environment shared by children in relation to oral health, despite widely differing medical, social and geographical contexts. The results of this empirical

  3. Early detection and longitudinal monitoring of experimental primary and disseminated melanoma using [{sup 18}F]ICF01006, a highly promising melanoma PET tracer

    Energy Technology Data Exchange (ETDEWEB)

    Rbah-Vidal, Latifa; Vidal, Aurelien; Besse, Sophie; Audin, Laurent; Degoul, Francoise; Miot-Noirault, Elisabeth; Moins, Nicole; Auzeloux, Philippe; Chezal, Jean-Michel [Clermont Universite, Universite d' Auvergne, Imagerie Moleculaire et Therapie Vectorisee, BP 10448, Clermont-Ferrand (France); Inserm, U 990, Clermont-Ferrand (France); Cachin, Florent [Clermont Universite, Universite d' Auvergne, Imagerie Moleculaire et Therapie Vectorisee, BP 10448, Clermont-Ferrand (France); Inserm, U 990, Clermont-Ferrand (France); Centre Jean Perrin, Clermont-Ferrand (France); Bonnet, Mathilde [U1071 INSERM-Universite d' Auvergne, M2USH, Clermont-Ferrand (France); Askienazy, Serge [CYCLOPHARMA Laboratories, Biopole Clermont-Limagne, Saint-Beauzire (France); Dolle, Frederic [CEA, I2BM, Service Hospitalier Frederic Joliot, Orsay (France)

    2012-09-15

    Here, we report a new and rapid radiosynthesis of {sup 18}F-N-[2-(diethylamino)ethyl]-6-fluoro-pyridine-3-carboxamide ([{sup 18}F]ICF01006), a molecule with a high specificity for melanotic tissue, and its evaluation in a murine model for early specific detection of pigmented primary and disseminated melanoma. [{sup 18}F]ICF01006 was synthesized using a new one-step bromine-for-fluorine nucleophilic heteroaromatic substitution. Melanoma models were induced by subcutaneous (primary tumour) or intravenous (lung colonies) injection of B16BL6 melanoma cells in C57BL/6J mice. The relevance and sensitivity of positron emission tomography (PET) imaging using [{sup 18}F]ICF01006 were evaluated at different stages of tumoural growth and compared to {sup 18}F-fluorodeoxyglucose ([{sup 18}F]FDG). The fully automated radiosynthesis of [{sup 18}F]ICF01006 led to a radiochemical yield of 61 % and a radiochemical purity >99 % (specific activity 70-80 GBq/{mu}mol; total synthesis time 42 min). Tumours were visualized before they were palpable as early as 1 h post-injection with [{sup 18}F]ICF01006 tumoural uptake of 1.64 {+-} 0.57, 3.40 {+-} 1.47 and 11.44 {+-} 2.67 percentage of injected dose per gram of tissue (%ID/g) at days 3, 5 and 14, respectively. [{sup 18}F]ICF01006 PET imaging also allowed detection of melanoma pulmonary colonies from day 9 after tumour cell inoculation, with a lung radiotracer accumulation correlated with melanoma invasion. At day 21, radioactivity uptake in lungs reached a value of 5.23 {+-} 2.08 %ID/g (versus 0.41 {+-} 0.90 %ID/g in control mice). In the two models, comparison with [{sup 18}F]FDG showed that both radiotracers were able to detect melanoma lesions, but [{sup 18}F]ICF01006 was superior in terms of contrast and specificity. Our promising results provide further preclinical data, reinforcing the excellent potential of [{sup 18}F]ICF01006 PET imaging for early specific diagnosis and follow-up of melanin-positive disseminated melanoma. (orig.)

  4. The Edward Teller Medal Lecture: the Evolution Toward Indirect Drive and Two Decades of Progress Toward Icf Ignition and Burn (lirpp Vol. 11)

    Science.gov (United States)

    Lindl, John D.

    2016-10-01

    In 1972, I joined the Livermore ICF Theory and Target Design group led by John Nuckolls, shortly after publication of John's seminal Nature article on ICF. My primary role, working with others in the target design program including Mordy Rosen, Steve Haan, and Larry Suter, has been as a target designer and theorist who utilized the LASNEX code to perform numerical experiments, which along with analysis of laboratory and underground thermonuclear experiments allowed me to develop a series of models and physical insights which have been used to set the direction and priorities of the Livermore program...

  5. Inversión espectral prestack simultánea de ondas PP y PS para la caracterización cuantitativa de capas delgadas

    Directory of Open Access Journals (Sweden)

    Ramsis Guerrero

    2012-06-01

    Full Text Available En este trabajo extendemos un método de inversión espectral para determinar las propiedades de una capa delgada y de los medios que se encuentran por encima y por debajo de la misma, a partir del espectro de amplitud de la respuesta sísmica prestack, con aplicación a la caracterización de reservorios asociados a estructuras con espesores por debajo del tunning. Estas propiedades incluyen el espesor de la capa delgada como así también las velocidades de las ondas compresionales y de corte, y las densidades de cada uno de los tres medios. Se presentan numerosos ejemplos utilizando datos sintéticos con ruido gaussiano generados a partir de diversos modelos de capas delgadas representativos de reservorios de gas de unos pocos metros de espesor. Se demuestra que, bajo ciertas condiciones, es posible obtener estimaciones razonables de los diversos parámetros involucrados utilizando el dato sísmico prestack convencional (ondas PP. Se analiza asimismo el impacto del uso de la información adicional provista por las ondas de corte convertidas (ondas PS, demostrándose que éstas contribuyen a mejorar significativamente las calidad de los resultados y a relajar las condiciones requeridas por el uso de las ondas PP solamente. Por último, y con el objetivo de reducir los problemas de no-unicidad inherentes a este tipo de problema inverso, las soluciones son forzadas a satisfacer, dentro de cierta tolerancia, la posible correlación existente entre las velocidades de las ondas P y S, y entre la velocidad de la onda P y la densidad, información a priori con frecuencia disponible a partir de datos de pozo. Como consecuencia, la incerteza en la estimación del espesor, velocidades y densidad de la capa delgada se reduce significativamente, lo que permite obtener soluciones más precisas y confiables.In this work, we extend a spectral inversion method for determining the properties of a thin bed and those of the media lying above and below it from

  6. Coordenação motora fina de escolares com dislexia e transtorno do déficit de atenção e hiperatividade Fine motor coordination of students with dyslexia and attention deficit disorder with hiperactivity

    Directory of Open Access Journals (Sweden)

    Paola Matiko Martins Okuda

    2011-10-01

    Full Text Available OBJETIVOS: descrever e comparar o desempenho da coordenação motora fina em escolares com dislexia e com transtorno do déficit de atenção e hiperatividade utilizando parâmetros de desempenho motor e idade cronológica da Escala de Desenvolvimento Motor. MÉTODO: participaram 22 escolaresdo ensino fundamental, de ambos os gêneros, na faixa etária de 6 a 11 anos de idade distribuídos em: GI: 11 escolares com transtorno do déficit de atenção e hiperatividade e GII: 11 com dislexia. Como procedimento, provas de motricidade fina da Escala de Desenvolvimento Motor foram aplicadas. RESULTADOS: os resultados revelaram diferença estatisticamente significante entre a idade motora fina e a idade cronológica de GI e GII. Conforme a classificação da Escala do Desenvolvimento Motor, 90% dos escolares de GI e GII apresentaram desenvolvimento motor fino muito inferior ao esperado para a idade e 10% dos escolares com dislexia apresentam desenvolvimento normal baixo ao esperado para a idade e 10% dos escolares com transtorno do déficit de atenção e hiperatividade apresentaram desenvolvimento inferior ao esperado para a idade. CONCLUSÃO: concluímos que tanto os escolares com dislexia como os com TDAH deste estudo apresentam atrasos na coordenação motora fina, demonstrando que os participantes desta pesquisa apresentam dificuldades em atividades que exijam destreza, quadro característico do transtorno do desenvolvimento da coordenação. Estudos complementares estão sendo conduzidos pelos autores deste estudo para poder verificar e comprovar se o perfil motor fino dos escolares encontrados neste estudo se assemelham ou se diferem de acordo com o quadro apresentado pelos mesmos.PURPOSE: to describe and compare the fine motor coordination performance of students with dyslexia and with Attention Deficit and Hyperactivity Disorder. METHOD: the study included 22 elementary school students of both genders, aged from 6 to 11-year old, divided into

  7. Punção aspirativa com agulha fina guiada por ultrassom e biópsia por videolaparoscopia em próstata de cães

    OpenAIRE

    T.M. Paula; G.H. Toniollo; D.K. Honsho; C.T.N. Duque; V. Páfaro; C. Momo

    2011-01-01

    Onze cães, sem raça definida, machos, adultos, não castrados e hígidos foram submetidos à punção aspirativa com agulha fina da próstata guiada por ultrassom para avaliação citológica e, após um período mínimo de sete dias, à videolaparoscopia para obtenção de fragmento prostático para avaliação histológica. Nos exames citológicos, dois animais apresentaram alterações celulares compatíveis com hiperplasia prostática benigna. Durante a videolaparoscopia, a colheita do fragmento prostático foi r...

  8. Descomposición y liberación de nutrimentos desde las raíces finas de los sistemas agroforestales de cacao con sombras de poró y laurel, en Turrialba, Costa Rica Descomposición y liberación de nutrimentos desde las raíces finas de los sistemas agroforestales de cacao con sombras de poró y laurel, en Turrialba, Costa Rica

    Directory of Open Access Journals (Sweden)

    Muñoz Arboleda Fernando

    2006-06-01

    Full Text Available

    Se usó el método de bolsas de descomposición para estudiar la pérdida de biomasa y liberación de N, P, K, Ca y Mg desde las raíces finas (<2 mm en los sistemas agroforestales de cacao con sombras de poró y laurel. Se muestrearon bolsas a las 1, 2, 4, 6, 12, 18 y 25 semanas en las épocas seca y lluviosa. Las tasas de descomposición y liberación de nutrimentos fueron bien descritas por un modelo exponencial doble. Se observó alta relación entre las tasas de pérdida de biomasa y liberación de N de las tres especies. Las tasas de liberación de nutrimentos fueron K > Mg > P > N > Ca. Después de una semana de incubación cerca del 90% del K fue liberado mientras que el Ca tendió a la acumulación. Las raíces de poró fueron las de más rápida descomposición y liberación de nutrimentos, excepto de K. El poró sería la especie de sombra adecuada para sistemas de producción que requieran rápida recirculación de nutrimentos. El laurel exhibió tasas lentas de descomposición y liberación de nutrimentos.

    Palabras claves: Agroforestería, Theobroma cacao, Erythrina poeppigiana, Cordia alliodora, recirculación de nutrimentos, descomposición de raíces finas.

  9. The International Classification of Disability, Functioning and Health (ICF) - an example of research methods and language in describing 'social functioning' in medical research

    DEFF Research Database (Denmark)

    Rasmussen, Gitte

    2016-01-01

    Medical research ventures into the area of social life with a holistic approach to health and disabilities. However, the specific language developed for this kind of research in the 'ICF' model (adopted by the UN) loses sight of the very phenomena it aims at describing. By contrast, based...

  10. 42 CFR 418.112 - Condition of participation: Hospices that provide hospice care to residents of a SNF/NF or ICF/MR.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Condition of participation: Hospices that provide hospice care to residents of a SNF/NF or ICF/MR. 418.112 Section 418.112 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM...

  11. Perspectives on the International Classification of Functioning, Disability, and Health: Child and Youth Version (ICF-CY) and Occupational Therapy Practice

    Science.gov (United States)

    Cramm, Heidi; Aiken, Alice B.; Stewart, Debra

    2012-01-01

    Classifying disability for children and youth has typically meant describing a diagnosis or developmental lag. The publication of the "International Classification of Functioning, Disability and Health: Child & Youth" version (ICF-CY) marks a global paradigm shift in the conceptualization and classification of childhood disability. Knowledge and…

  12. Adding a subjective dimension to an ICF-based disability measure for people with multiple sclerosis : development and use of a measure for perception of disabilities

    NARCIS (Netherlands)

    Wynia, K.; Middel, B.; de Ruiter, H.; van Dijk, J.P.; Lok, W.S.; De Keyser, J.H.; Reijneveld, S.A.

    2009-01-01

    Objective. The subjective dimension of disability, the perception of disability, is a dimension missing from the International Classification of Functioning, Disability and Health (ICF), and from health-related quality of life (HRQOL) instruments. However, it is a highly relevant dimension for clini

  13. Generation of an ICF Syndrome Model by Efficient Genome Editing of Human Induced Pluripotent Stem Cells Using the CRISPR System

    Directory of Open Access Journals (Sweden)

    Izuho Hatada

    2013-09-01

    Full Text Available Genome manipulation of human induced pluripotent stem (iPS cells is essential to achieve their full potential as tools for regenerative medicine. To date, however, gene targeting in human pluripotent stem cells (hPSCs has proven to be extremely difficult. Recently, an efficient genome manipulation technology using the RNA-guided DNase Cas9, the clustered regularly interspaced short palindromic repeats (CRISPR system, has been developed. Here we report the efficient generation of an iPS cell model for immunodeficiency, centromeric region instability, facial anomalies syndrome (ICF syndrome using the CRISPR system. We obtained iPS cells with mutations in both alleles of DNA methyltransferase 3B (DNMT3B in 63% of transfected clones. Our data suggest that the CRISPR system is highly efficient and useful for genome engineering of human iPS cells.

  14. Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system.

    Science.gov (United States)

    Horii, Takuro; Tamura, Daiki; Morita, Sumiyo; Kimura, Mika; Hatada, Izuho

    2013-09-30

    Genome manipulation of human induced pluripotent stem (iPS) cells is essential to achieve their full potential as tools for regenerative medicine. To date, however, gene targeting in human pluripotent stem cells (hPSCs) has proven to be extremely difficult. Recently, an efficient genome manipulation technology using the RNA-guided DNase Cas9, the clustered regularly interspaced short palindromic repeats (CRISPR) system, has been developed. Here we report the efficient generation of an iPS cell model for immunodeficiency, centromeric region instability, facial anomalies syndrome (ICF) syndrome using the CRISPR system. We obtained iPS cells with mutations in both alleles of DNA methyltransferase 3B (DNMT3B) in 63% of transfected clones. Our data suggest that the CRISPR system is highly efficient and useful for genome engineering of human iPS cells.

  15. Quantifying low-mode shell asymmetry as a means to predict ICF implosion performance on the NIF

    Science.gov (United States)

    Nora, Ryan; Spears, Brian; Tommasini, Riccardo; Peterson, J. Luc; Field, John; Springer, Paul; Gaffney, Jim; Hammer, Jim; Kritcher, Annie

    2015-11-01

    Low mode fuel and ablator asymmetries are a significant degradation mechanism in NIF indirect drive ICF implosions. These asymmetries are forced by radiation drive asymmetry stemming from asymmetric hohlraum wall illumination. We develop an ensemble of two, three, and four-shock high-density-carbon ablator simulations with varying drive asymmetries and convergence ratios. We use this ensemble to relate the shell properties prior to its peak implosion velocity to the overall implosion performance and extend this technique to analyze NIF in-flight radiograph (convergent ablator) experimental data. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  16. Aspects of functioning and environmental factors in medical work capacity evaluations of persons with chronic widespread pain and low back pain can be represented by a combination of applicable ICF Core Sets

    Directory of Open Access Journals (Sweden)

    Schwegler Urban

    2012-12-01

    Full Text Available Abstract Background Medical work capacity evaluations play a key role in social security schemes because they usually form the basis for eligibility decisions regarding disability benefits. However, the evaluations are often poorly standardized and lack transparency as decisions on work capacity are based on a claimant’s disease rather than on his or her functional capacity. A comprehensive and consistent illustration of a claimant’s lived experience in relation to functioning, applying the International Classification of Functioning, Disability and Health (ICF and the ICF Core Sets (ICF-CS, potentially enhances transparency and standardization of work capacity evaluations. In our study we wanted to establish whether and how the relevant content of work capacity evaluations can be captured by ICF-CS, using disability claimants with chronic widespread pain (CWP and low back pain (LBP as examples. Methods Mixed methods study, involving a qualitative and quantitative content analysis of medical reports. The ICF was used for data coding. The coded categories were ranked according to the percentage of reports in which they were addressed. Relevance thresholds at 25% and 50% were applied. To determine the extent to which the categories above the thresholds are represented by applicable ICF-CS or combinations thereof, measures of the ICF-CS’ degree of coverage (i.e. content validity and efficiency (i.e. practicability were defined. Results Focusing on the 25% threshold and combining the Brief ICF-CS for CWP, LBP and depression for CWP reports, the coverage ratio reached 49% and the efficiency ratio 70%. Combining the Brief ICF-CS for LBP, CWP and obesity for LBP reports led to a coverage of 47% and an efficiency of 78%. Conclusions The relevant content of work capacity evaluations involving CWP and LBP can be represented by a combination of applicable ICF-CS. A suitable standard for documenting such evaluations could consist of the Brief ICF

  17. Caracterización de la capa de boruros formada durante la austenización de un hierro nodular austemperizado//Characterization of borides coating formed during austenitization of an austempered ductile iron

    Directory of Open Access Journals (Sweden)

    Urbano Ordóñez‐Hernández

    2015-01-01

    Full Text Available En este trabajo se ha investigado el efecto de la austenitización y el borurado simultáneos, a 950 ºC, en la microestructura, la microdureza Vickers y el espesor de la capa borurada en medio líquido de un hierro nodular austemperizado no aleado. Se demostró que es posible obtener una capa de boruros de hierro muy bien estructurada con la microdureza Vickers suficientemente alta (1400 HVy con adecuado espesor de capa de 67 μm, sobre un sustrato de ausferrita típico de las fundiciones nodulares austemperizadas. Por medio de un ensayo pin on disc modificado, se comprobó la superior resistencia al desgaste abrasivo de la capa de boruros depositada durante la austenización del ADI, comparada con la máxima obtenida durante el austempering de éste sin aplicar el recubrimiento.Palabras claves: hierro nodular, borurado, austenización, austemperizado.______________________________________________________________________________AbstractThe effect of simultaneous austenitization and boriding at 950 ºC, on microstructure, Vickers hardness and boronized layer thickness of a non alloyed austempered ductile iron has been investigated. It was demonstrated that it is possible to obtain a well formed boronized layer with a Vicker hardness sufficiently high (1400 HV, and with an appropriated 67μm layer thickness, on a typical ausferrite ADI substrate. By using a modified pin on disc test, it was demonstrated the higher abrasion wear resistance of borides layer deposited during ADI austenitization process, compared with Vickers hardness of low temperature noncoated austempered ductile iron.Key words: ductile iron, boriding, austenitization, austempering.

  18. 制药企业质量管理体系中纠正与预防措施(CAPA)的实施%The Implementation of Corrective and Preventive Action in Pharmaceutical Companies'Quality Management System

    Institute of Scientific and Technical Information of China (English)

    丁晓玥; 梁毅

    2011-01-01

    纠正与预防措施(CAPA)作为质量管理体系的重要组成部分,我国即将颁布的新版GMP也明确了建立CAPA体系的要求.本文从制药企业的角度详细讨论了CAPA的实施步骤,从而提高企业的质量管理水平.

  19. A QUARTA CAPA DE LIVROS DIDÁTICOS DE INGLÊS À LUZ DA TEORIA DE GÊNEROS DA ESCOLA DE SIDNEY.

    Directory of Open Access Journals (Sweden)

    Renato Caixeta Silva

    2016-06-01

    Full Text Available Resumo: Neste trabalho, apresenta-se a análise do gênero quarta capa de livros didáticos de inglês com base nas ideias sobre gênero da Escola de Sidney, considerando-o como parte do contexto cultural escolar e comercial. Apresentam-se, primeiramente, os referenciais teóricos dessa Escola, e nesta linha, a ideia de gênero como uma atividade linguística e social organizada em estágios e voltada a objetivos, que tem uma configuração contextual e elementos com objetivos inerentes. Também é feita uma análise linguístico-discursiva de aspectos ideacionais e interpessoais de dois exemplares do gênero com base na proposta de Martin e Rose (2003 e 2007, evidenciando que o livro didático de inglês é representado, nesse gênero, como agente importante nos processos de ensino e aprendizagem. Por fim, argumenta-se sobre a implicação deste trabalho para cursos de formação docente.

  20. Caracterización de la capa y el filo adherido en el mecanizado de la aleación AA7050

    Directory of Open Access Journals (Sweden)

    Sánchez-Sola, J. M.

    2005-12-01

    Full Text Available The built-up edge (BUE and the built-up layer (BUL are the most common adhesion effects that can take place in the metal machining processes. Surface finish quality and tool life can be negatively affected by BUL and BUE. This work reports the results of a study on the microstructural differences between BUL and BUE formed in AA7050 cutting processes. From this study, it can be concluded that different mechanisms are the responsible of BUL and BUE. Thus, BUL and BUE cannot be considered as different forms of the same effect.

    El filo recrecido (BUE y capa adherida (BUL son los principales efectos de incorporación de material mecanizado a la herramienta de corte. Ambos, se enmarcan dentro de los denominados efectos de adhesión. La existencia de BUL y BUE puede influir de forma directa sobre la calidad de acabado superficial de la pieza e indirectamente sobre el desgaste de la propia herramienta. En el presente trabajo se analizan las diferencias microestructurales entre el BUL y el BUE, formados en el mecanizado de la aleación AA7050. Estas diferencias ponen de manifiesto que, al menos en las aleaciones estudiadas, ambos fenómenos están gobernados por distintos mecanismos y, por tanto, no pueden considerarse como formas diferentes de un mismo efecto.

  1. Caracterização morfológica, determinação do nível de ploidia e viabilidade do pólen de uma progênie de tangerineira 'Clementina Fina' e 'Montenegrina'

    Directory of Open Access Journals (Sweden)

    Roberto Luis Weiler

    2011-01-01

    Full Text Available As plantas cítricas possuem ampla variação morfológica e citogenética. Neste contexto, análises dessas plantas podem auxiliar na identificação de materiais mais promissores para cruzamentos. Uma população de tangerineiras híbridas oriundas do cruzamento das tangerineiras 'Clementina Fina' (Citrus clementina Hort. ex Tan. e 'Montenegrina' (Citrus deliciosa Ten. foi avaliada segundo características morfológicas, época de maturação, número cromossômico e viabilidade de pólen. Foi possível distinguir as 94 plantas da progênie e os genitores através dos dados morfológicos. Verificou-se uma alteração no período de maturação dos frutos nas plantas híbridas. Todas as plantas avaliadas são diplóides com um número cromossômico de 2n=18, bem como, alto grau de viabilidade de pólen, variando entre 79,0% e 98,1%.

  2. Punção aspirativa com agulha fina guiada por ultrassom e biópsia por videolaparoscopia em próstata de cães

    Directory of Open Access Journals (Sweden)

    T.M. Paula

    2011-08-01

    Full Text Available Onze cães, sem raça definida, machos, adultos, não castrados e hígidos foram submetidos à punção aspirativa com agulha fina da próstata guiada por ultrassom para avaliação citológica e, após um período mínimo de sete dias, à videolaparoscopia para obtenção de fragmento prostático para avaliação histológica. Nos exames citológicos, dois animais apresentaram alterações celulares compatíveis com hiperplasia prostática benigna. Durante a videolaparoscopia, a colheita do fragmento prostático foi realizada de maneira rápida, não sendo observada hemorragia significativa após o procedimento. Os animais não apresentaram nenhuma complicação no período pós-operatório. Verificaram-se, ao exame histológico, morfologia e estrutura celulares e teciduais nos padrões normais do parênquima prostático em 10 animais; um único cão apresentou alterações celulares e teciduais sugestivas de hiperplasia prostática benigna.

  3. Moderators, mediators, and bidirectional relationships in the International Classification of Functioning, Disability and Health (ICF) framework: An empirical investigation using a longitudinal design and Structural Equation Modeling (SEM).

    Science.gov (United States)

    Rouquette, Alexandra; Badley, Elizabeth M; Falissard, Bruno; Dub, Timothée; Leplege, Alain; Coste, Joël

    2015-06-01

    The International Classification of Functioning, Disability and Health (ICF) published in 2001 describes the consequences of health conditions with three components of impairments in body structures or functions, activity limitations and participation restrictions. Two of the new features of the conceptual model were the possibility of feedback effects between each ICF component and the introduction of contextual factors conceptualized as moderators of the relationship between the components. The aim of this longitudinal study is to provide empirical evidence of these two kinds of effect. Structural equation modeling was used to analyze data from a French population-based cohort of 548 patients with knee osteoarthritis recruited between April 2007 and March 2009 and followed for three years. Indicators of the body structure and function, activity and participation components of the ICF were derived from self-administered standardized instruments. The measurement model revealed four separate factors for body structures impairments, body functions impairments, activity limitations and participation restrictions. The classic sequence from body impairments to participation restrictions through activity limitations was found at each assessment time. Longitudinal study of the ICF component relationships showed a feedback pathway indicating that the level of participation restrictions at baseline was predictive of activity limitations three years later. Finally, the moderating role of personal (age, sex, mental health, etc.) and environmental factors (family relationships, mobility device use, etc.) was investigated. Three contextual factors (sex, family relationships and walking stick use) were found to be moderators for the relationship between the body impairments and the activity limitations components. Mental health was found to be a mediating factor of the effect of activity limitations on participation restrictions.

  4. Normal histone modifications on the inactive X chromosome in ICF and Rett syndrome cells: implications for methyl-CpG binding proteins

    Directory of Open Access Journals (Sweden)

    Canfield Theresa K

    2004-09-01

    Full Text Available Abstract Background In mammals, there is evidence suggesting that methyl-CpG binding proteins may play a significant role in histone modification through their association with modification complexes that can deacetylate and/or methylate nucleosomes in the proximity of methylated DNA. We examined this idea for the X chromosome by studying histone modifications on the X chromosome in normal cells and in cells from patients with ICF syndrome (Immune deficiency, Centromeric region instability, and Facial anomalies syndrome. In normal cells the inactive X has characteristic silencing type histone modification patterns and the CpG islands of genes subject to X inactivation are hypermethylated. In ICF cells, however, genes subject to X inactivation are hypomethylated on the inactive X due to mutations in the DNA methyltransferase (DNMT3B genes. Therefore, if DNA methylation is upstream of histone modification, the histones on the inactive X in ICF cells should not be modified to a silent form. In addition, we determined whether a specific methyl-CpG binding protein, MeCP2, is necessary for the inactive X histone modification pattern by studying Rett syndrome cells which are deficient in MeCP2 function. Results We show here that the inactive X in ICF cells, which appears to be hypomethylated at all CpG islands, exhibits normal histone modification patterns. In addition, in Rett cells with no functional MeCP2 methyl-CpG binding protein, the inactive X also exhibits normal histone modification patterns. Conclusions These data suggest that DNA methylation and the associated methyl-DNA binding proteins may not play a critical role in determining histone modification patterns on the mammalian inactive X chromosome at the sites analyzed.

  5. Application study of the components Activity and Participation of the ICF Checklist used in people with Multiple Sclerosis and its relation to the Core Sets

    Directory of Open Access Journals (Sweden)

    Rosé Colom Toldrá

    2016-10-01

    Full Text Available Introduction: The Core Set is a group of typical and significant functionality categories of the International Classification of Functioning, Disability and Health – ICF used for certain health conditions. Objective: The study reviewed the application of the component categories Activities and Participation based on the ICF Checklist for multiple sclerosis (MS and its relationship with the comprehensive and validated Core Sets by occupational therapists. Method: Descriptive quantitative research from collection and organization of data questionnaire based on the components Activities and Participation of the ICF Checklist - Version 2.1ª. Clinical form for the ICF containing 25 categories belonging to 6 domains and analysis of its relationship with the Core Sets. Participated 115 people with relapsing-remitting MS without disability to moderate disability, treated at the Central Institute of Hospital Clinics of the Faculty of Medicine University of São Paulo. We created database in Excel and made descriptive analysis of frequencies. Results: Most participants were women (85, mean age 32 years and 1 month (± 7.4. Study broadens the evidence of the applicability of the Comprehensive Core Set with 88% (22 and Core Set validated by occupational therapists with 72% (18 compared evaluated categories. More significant difficulties were encountered in the categories d640 Doing housework, d430 Lifting and carrying objects and d850 Remunerative employment, which reflected on the performance of various activities and social participation. Conclusion: Studies on application of the Core Set validated by occupational therapists are recommended to extend the evidence of professional clinical practice and inclusion of categories depending on the context.

  6. Improving reliability of timing system in ICF driver based on FMECA method%ICF同步触发信号传输的可靠性研究

    Institute of Scientific and Technical Information of China (English)

    唐菱; 陈骥; 黄夏; 汪凌芳; 王超; 李克洪; 党钊

    2014-01-01

    为提高惯性约束聚变(ICF)装置同步触发信号传输可靠性,收集、整理了该传输系统的故障,并将故障模式、影响和危害性分析(FMECA)方法应用到同步触发信号传输系统,故障模式危害度最高的两类故障为同步触发信号时序漂移和同步触发信号受到干扰,并在此基础上提出了相应的改进措施,开展了可靠性验证试验,试验研究结果表明,该方法将原型装置同步触发信号传输的可靠性成功地提高至平均无故障发次大于1256发,并为 ICF 激光装置的可靠性研究提供了一种可行、有效的方法。%Failure Mode and Effects and Criticality Analysis(FMECA) of timing system in SG-III prototype is developed in order to improve the reliability of time system in Inertial Confinement Fusion(ICF) facility. This work effectively analyzes the most severe faults, concludes the disadvantages of the timing system, and puts forward improvement methods. The experimental results show that FMECA has successfully improved the reliability of the timing system, enabling the mean shot between failures above 1 256 shots. This work can provide a feasible and effective method for studying on the reliability of laser facility for ICF.

  7. Effects of molecular weight of PVA on formation, stability and deformation of compound droplets for ICF polymer shells

    Science.gov (United States)

    Liu, Meifang; Zheng, Yueqing; Li, Jie; Chen, Sufen; Liu, Yiyang; Li, Jing; Li, Bo; Zhang, Zhanwen

    2017-01-01

    Sphericity and wall thickness uniformity are some of the hardest specifications to fulfill, as required by inertial confined fusion (ICF) research for polymer shells prepared by the microencapsulation technique. Driven by the need to control the deformation of compound droplets, the effects of the molecular weight of poly(vinyl alcohol) (PVA) on the formation and stability of the droplets, as well as the sphericity and wall thickness uniformity of the resulting shells, were investigated. On increasing the molecular weight of the PVA, the densities of the external water phases (W2) are almost the same, but the viscosity of the W2 phase increases more quickly than the interfacial tension. This makes the detaching force increase more quickly than the upward one, causing the formation of compound droplets and detachment from the oil tube. On the other hand, the increase in interfacial tension makes the maximum pressures ( P max) in the O phase (O) of the compound droplets increase, causing them to rupture easily and decreasing their stability. However, for PVA with the same molecular weight, the viscous shear force in the flowing field reduces the role of gravity and makes the inner water droplet move towards the center of the compound droplet, decreasing its P max in the flowing field and improving its stability. Moreover, during the solidifying process, the viscous shear force increases more quickly than the interfacial tension force due to the quicker increase in viscosity with an increase in the molecular weight of the PVA. The increase in the viscous shear force can make the droplets deform, resulting in a decrease in their sphericity. However, the appropriate viscous shear force can also center the compound droplet—although they become decentered when the viscous shear force is too large, leading to the wall thickness uniformity increasing at first before decreasing quickly. The results presented in this work provide a more in-depth understanding of the

  8. Advances and Challenges In Uncertainty Quantification with Application to Climate Prediction, ICF design and Science Stockpile Stewardship

    Science.gov (United States)

    Klein, R.; Woodward, C. S.; Johannesson, G.; Domyancic, D.; Covey, C. C.; Lucas, D. D.

    2012-12-01

    Uncertainty Quantification (UQ) is a critical field within 21st century simulation science that resides at the very center of the web of emerging predictive capabilities. The science of UQ holds the promise of giving much greater meaning to the results of complex large-scale simulations, allowing for quantifying and bounding uncertainties. This powerful capability will yield new insights into scientific predictions (e.g. Climate) of great impact on both national and international arenas, allow informed decisions on the design of critical experiments (e.g. ICF capsule design, MFE, NE) in many scientific fields, and assign confidence bounds to scientifically predictable outcomes (e.g. nuclear weapons design). In this talk I will discuss a major new strategic initiative (SI) we have developed at Lawrence Livermore National Laboratory to advance the science of Uncertainty Quantification at LLNL focusing in particular on (a) the research and development of new algorithms and methodologies of UQ as applied to multi-physics multi-scale codes, (b) incorporation of these advancements into a global UQ Pipeline (i.e. a computational superstructure) that will simplify user access to sophisticated tools for UQ studies as well as act as a self-guided, self-adapting UQ engine for UQ studies on extreme computing platforms and (c) use laboratory applications as a test bed for new algorithms and methodologies. The initial SI focus has been on applications for the quantification of uncertainty associated with Climate prediction, but the validated UQ methodologies we have developed are now being fed back into Science Based Stockpile Stewardship (SSS) and ICF UQ efforts. To make advancements in several of these UQ grand challenges, I will focus in talk on the following three research areas in our Strategic Initiative: Error Estimation in multi-physics and multi-scale codes ; Tackling the "Curse of High Dimensionality"; and development of an advanced UQ Computational Pipeline to enable

  9. Contextual factors of the ICF as a tool for analysis of the implications of physical disability for a group of patients under Occupational Therapy care

    Directory of Open Access Journals (Sweden)

    Rosé Colom Toldrá

    2014-09-01

    Full Text Available This article analyzes the implications of the acquisition of physical disability on everyday life situations of persons under occupational therapy care using the International Classification of Functioning, Disability and Health – ICF, with emphasis on contextual factors. The study included 11 adults and elderly with physical impairments resulting from neurological disorders who were under Occupational Therapy care at the Center for Teaching and Research at the University of Sao Paulo from 2009 to 2010. It’s an exploratory qualitative research conducted through documentary study and semi-structured interview for the administration of the ICF components. Changes in body functions are diverse, both mental and related to movement, and when coupled with contextual factors may result in different levels and types of disabilities, preventing participation in life situations. The analysis of contextual factors helps to identify and relate personal and environmental aspects and their dynamic interaction reflects processes that may cause disability, establishing the ICF as a valuable guide for research and development of rehabilitation practices that consider the different aspects of the reality of a person’s life.

  10. Exploring the relationships between International Classification of Functioning, Disability and Health (ICF constructs of Impairment, Activity Limitation and Participation Restriction in people with osteoarthritis prior to joint replacement

    Directory of Open Access Journals (Sweden)

    Johnston Marie

    2011-05-01

    Full Text Available Abstract Background The International Classification of Functioning, Disability and Health (ICF proposes three main constructs, impairment (I, activity limitation (A and participation restriction (P. The ICF model allows for all paths between the constructs to be explored, with significant paths likely to vary for different conditions. The relationships between I, A and P have been explored in some conditions but not previously in people with osteoarthritis prior to joint replacement. The aim of this paper is to examine these relationships using separate measures of each construct and structural equation modelling. Methods A geographical cohort of 413 patients with osteoarthritis about to undergo hip and knee joint replacement completed the Aberdeen measures of Impairment, Activity Limitation and Participation Restriction (Ab-IAP. Confirmatory factor analysis was used to test the three factor (I, A, P measurement model. Structural equation modelling was used to explore the I, A and P pathways in the ICF model. Results There was support from confirmatory factor analysis for the three factor I, A, P measurement model. The structural equation model had good fit [S-B Chi-square = 439.45, df = 149, CFI robust = 0.91, RMSEA robust = 0.07] and indicated significant pathways between I and A (standardised coefficient = 0.76 p Conclusion The significant pathways suggest that treatments and interventions aimed at reducing impairment, such as joint replacement, may only affect P indirectly, through A, however, longitudinal data would be needed to establish this.

  11. GÉNEROS BACTERIANOS DOMINANTES EN LOS ESTRATOS FOLIARES DEL TABACO CURADO PARA CAPAS. INFLUENCIA DE LA NICOTINA Y EL pH SOBRE SU DENSIDAD POBLACIONAL

    Directory of Open Access Journals (Sweden)

    Yunior M. Morán Gómez

    2013-01-01

    Full Text Available Aunque las bacterias juegan un papel importante en el proceso fermentativo del tabaco, en Cuba no se han identificado los géneros presentes en el tabaco curado para capas, ni las variables que afectan a sus poblaciones. Este conocimiento pudiera contribuir al manejo de los procesos en los que estos microorganismos intervienen. El objetivo de esta investigación fue determinar la relación que existe entre la densidad poblacional de los géneros bacterianos dominantes en los diferentes estratos foliares de la planta de tabaco luego de la curación y la concentración de nicotina y los valores de pH en estos ambientes. Se realizó el aislamiento e identificación genérica de la microbiota bacteriana y se determinó el contenido de nicotina y el pH de las hojas de tabaco para cada estrato foliar. Las poblaciones de Bacillus en todos los estratos foliares siempre fueron superiores a otros géneros aislados como Staphylococcus y Arthrobacter . Desde los niveles foliares inferiores hasta los superiores el contenido de nicotina se incrementó significativamente, el pH mostró una ligera disminución (no significativa p<0,01 y disminuyó la densidad poblacional de bacterias de todos los géneros aislados. El modelo de regresión reveló que la disminución de la densidad poblacional de los géneros bacterianos que se aprecia al ascender por los diferentes niveles foliares estuvo más relacionada con el incremento de la concentración de nicotina en las hojas que con la variación del pH.

  12. Dynamics of a Z Pinch X Ray Source for Heating ICF Relevant Hohlraums to 120-160eV

    Energy Technology Data Exchange (ETDEWEB)

    SANFORD,THOMAS W. L.; OLSON,RICHARD E.; MOCK,RAYMOND CECIL; CHANDLER,GORDON A.; LEEPER,RAMON J.; NASH,THOMAS J.; RUGGLES,LAURENCE E.; SIMPSON,WALTER W.; STRUVE,KENNETH W.; PETERSON,D.L.; BOWERS,R.L.; MATUSKA,W.

    2000-07-10

    A z-pinch radiation source has been developed that generates 60 {+-} 20 KJ of x-rays with a peak power of 13 {+-} 4 TW through a 4-mm diameter axial aperture on the Z facility. The source has heated NIF (National Ignition Facility)-scale (6-mm diameter by 7-mm high) hohlraums to 122 {+-} 6 eV and reduced-scale (4-mm diameter by 4-mm high) hohlraums to 155 {+-} 8 eV -- providing environments suitable for indirect-drive ICF (Inertial Confinement Fusion) studies. Eulerian-RMHC (radiation-hydrodynamics code) simulations that take into account the development of the Rayleigh-Taylor instability in the r-z plane provide integrated calculations of the implosion, x-ray generation, and hohlraum heating, as well as estimates of wall motion and plasma fill within the hohlraums. Lagrangian-RMHC simulations suggest that the addition of a 6 mg/cm{sup 3} CH{sub 2} fill in the reduced-scale hohlraum decreases hohlraum inner-wall velocity by {approximately}40% with only a 3--5% decrease in peak temperature, in agreement with measurements.

  13. Prevalence of Mental Disorders in the Elderly in the Community of Madrid: Results of the Mentdis_ICF65+ Study.

    Science.gov (United States)

    Ausín, Berta; Muñoz, Manuel; Santos-Olmo, Ana Belén; Pérez-Santos, Eloísa; Castellanos, Miguel A

    2017-02-06

    The MentDis_ICF65+ Project is an epidemiological study of mental disorders in people 65 to 85 years old in several European cities, including Madrid. Its aim is to determine the lifetime, 12-month, and 1-month prevalence of the main mental disorders in the elderly. The relationship of age and sex with each mental disorder was examined. The sample was collected through random sampling of people over 65 in Madrid, and consisted of 555 persons between 65 and 85 years old. The CIDI65+ was administered. Estimates of prevalence and odds ratios (OR) were made using sample frequencies and according to sex and age. Excluding nicotine dependence, 40.12% of the sample was found to have suffered a mental disorder at some time in their lives, 29.89% in the past year, and 17.70% were currently suffering from a mental disorder. The disorders with the highest prevalence rates were anxiety disorders, alcohol-related disorders, and mood disorders. Elderly women had a higher risk of suffering an anxiety disorder (OR men/women 0.42; CI 0.25-0.68) with a significance level of p disorder (OR men/women 3.96; CI 1.62-11.07) with a significance level of p disorder's prevalence decreased with age (OR 65-74/75-85, 1.85; CI 1.25-2.75) with a significance level of p mental health services for people over 65, are highlighted.

  14. Generation of Nonlinear Force Driven Blocks from Skin Layer Interaction of Petawatt-Picosecond Laser Pulses for ICF

    Institute of Scientific and Technical Information of China (English)

    Heinrich Hora; K. Jungwirth; B. Kralikova; J. Kraska; L. Laska; Liu Hong; G.H. Miley; P. Parys; Peng Hansheng; M. Pfeifer; K. Rohlena; Cang Yu; J. Skala; Z. Skladanowski; L. Torrisi; J. Ullschmied; J. Wolowski; Zhang Weiyan; He Xiantu; Zhang Jie; F. Osman; J. Badziak; F.P. Boody; S. Gammino; R. H(o)pfl

    2004-01-01

    The discovery of the essential difference of maximum ion energy for TW-ps laser plasma interaction compared with the 100 ns laser pulses [1] led to the theory of a skin layer model [2] where the control of prepulses suppressed the usual relativistic self-focusing. The subsequent generation of two nonlinear force driven blocks has been demonstrated experimentally and in extensive numerical studies where one block moves against the laser light and the other block into the irradiated target. These blocks of nearly solid state density DT plasma correspond to ion beam current densities [3] exceeding 1010 A/cm2 where the ion velocity can be chosen up to highly relativistic values. Using the results of the expected ignition of DT fuel by light ion beams, a selfsustained fusion reaction front may be generated even into uncompressed solid DT fuel similar to the Nuckolls-Wood [4] scheme where 10 kJ laser pulses produce 100 MJ fusion energy. This new and simplified scheme of laser-ICF needs and optimisation of the involved parameters.

  15. Measurement of the hot spot electron temperature in NIF ICF implosions using Krypton x-ray emission spectroscopy

    Science.gov (United States)

    Ma, T.; Chen, H.; Patel, P. K.; Schneider, M.; Barrios, M.; Berzak Hopkins, L.; Casey, D.; Chung, H.-K.; Hammel, B.; Jarrott, C.; Nora, R.; Pak, A.; Scott, H.; Spears, B.; Weber, C.

    2015-11-01

    The inference of ion temperature from neutron spectral measurements in indirect-drive ICF implosions is known to be sensitive to non-thermal velocity distributions in the fuel. The electron temperature (Te) inferred from dopant line ratios should not be sensitive to these bulk motions and hence may be a better measure of the thermal temperature of the hot spot. Here we describe a series of experiments to be conducted on the NIF where a small concentration of a mid-Z dopant (Krypton) is added to the fuel gas. The x-ray spectra is measured and the electron temperature is inferred from Kr line ratios. We also quantify the level of radiative cooling in the hot spot due to this mid-Z dopant. These experiments represent the first direct measurement of hot spot Te using spectroscopy, and we will describe the considerations for applying x-ray spectroscopy in such dense and non-uniform hot spots. This work performed under the auspices of U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  16. Design and analysis of a 2-DOF RFM for the mirror sub-assembly (MSA) of ICF facility

    Science.gov (United States)

    Wang, Baoxu; Zhu, Mingzhi; Chen, Xiaojuan; Chen, Gang; Fu, Xuenong

    2016-10-01

    This paper presents the design of a 2 degree-of-freedom (DOF) rotation flexure mechanism (RFM) that could be utilized as the pivot for the mirror sub-assembly (MSA) of transport mirrors in the target area of inertial confinement fusion (ICF) laser systems. The hybrid spring system is established as the analytical model of the 2-DOF RFM. With the suitable matrix in coordinate transformation, the overall compliance matrix is developed to reveal the compliance property of the mechanism and the compliance equations are obtained. The analytical results obtained from the compliance equations are validated by means of finite element analysis (FEA) with the accuracy of 1%. The compliance property and design tradeoffs of the 2-DOF RFM are discussed with the compliance equations. The 2-DOF RFM for the MSA of transport mirrors of ShenGuangIII (SGIII) facility is designed and optimized. Then, the MSA is modeled and analyzed by FEA. The analysis result shows that the 2-DOF RFM is feasible for the MSA design.

  17. Comparação entre a citopatologia por biopsia com agulha fina e a histopatologia no diagnóstico das neoplasias cutâneas e subcutâneas de cães

    Directory of Open Access Journals (Sweden)

    Paulo H. Braz

    2016-03-01

    Full Text Available Resumo: Os neoplasmas cutâneos estão entre os mais diagnosticados em medicina veterinária, diante disso busca-se que o diagnóstico desses tumores seja rápido e eficaz. Em medicina veterinária o uso da citopatologia como método para diagnóstico tornou-se crescente. Diante disso, é necessário que estudos comprovem a eficiência da técnica para que a mesma possa ser usada de maneira isolada. Este trabalho teve como objetivo comparar o diagnóstico obtido pelas técnicas citopatológica e histopatológica de tumores cutâneos e subcutâneos de cães, determinar qual o tipo neoplásico mais facilmente diagnosticado pela citopatologia e a neoplasia mais prevalente nesses animais, atendidos em dois hospitais veterinários de Campo Grande/MS, no período de março de 2012 a dezembro de 2013. Foram coletadas amostras celulares de tumores de 91 cães, através de punção aspirativa por agulha fina e punch cirúrgico Os resultados citopatológicos demonstraram uma eficácia de 69,69%, em relação à histopatologia. Para a diferenciação entre tumores neoplásicos e não neoplásicos, a eficiência aumenta, com resultados iguais em 91,91%. Para diferenciar tumores benignos de malignos, foi possível chegar a uma concordância na ordem de 68,13%. Os tumores mais prevalentes foram o mastocitoma, seguido do lipoma, fibrossarcoma e tumor de célula basal.

  18. Nuevas orientaciones para calcular la profundidad efectiva de la capa endurecida en engranajes de acero cementado // New orientations to calculate the effective depth of the layer hardened in engagements of cemented steel

    Directory of Open Access Journals (Sweden)

    G. González Rey

    1999-07-01

    Full Text Available Se exponen y discuten los inconvenientes de las clásicas y conocidas recomendaciones para decidir el espesor efectivo de capaendurecida en los dientes cementados de engranajes cilíndricos y cónicos. Además, se exponen los recientes trabajo realizados porISO TC60/WG 14 en la normalización de la profundidad efectiva de capa cementada, tomando como base las propuestas alemana yestadounidense. Es verificada mediante 5 ejemplos la aplicabilidad del estado actual de las recomendaciones de profundidad efectivade capa cementada en los engranajes sin riesgo de fragilidad y capaz de garantizar la resistencia mecánica necesaria en los flancos delos dientes ante el daño por exfoliación (case crushing o picadura superficial.Palabras claves: engranajes, cementado, norma ISO, espesor de capa endurecida.________________________________________________________________________________Abstract.Inconvenience of the classics and known recommendations to decide the effective case thickness toughened in the cemented teeth ofcylindrical and bevel gears are exposed and discussed. Furthermore, the recent work accomplished by ISO TC60/WG 14 in thenormalization of the cemented effective depth are exposed taking as base the German and American proposals. It is verified through5 examples the applicability of the current state of the effective depth recommendations of cap cemented in the gears withoutfragility risk and capable of guaranteeing the necessary mechanical resistance in the flanks of the teeth before the damage by casecrushing or pitting.Key words: gears case hardened, effective depth and ISO Standards.

  19. Reacción de la dentina a los sistemas adhesivos resinosos: aspectos biológicos relacionados y biodegradación de la capa híbrida

    OpenAIRE

    Hidalgo Lostaunau, Rony Christian; Docente del Diplomado en Odontología Estética Funcional. Unidad de Segunda Especialización. Facultad de Estomatología. Universidad Inca Garcilaso de la Vega. Lima,

    2014-01-01

    La adhesión con sistemas adhesivos resinosos en dentina está siendo cuestionada, los estudios longitudinales in vivo y de envejecimiento in vitro al respecto demuestran que existe una degradación de la capa híbrida a nivel de las paredes pulpares del diseño cavitario. El presente artículo plantea una síntesis de numerosas conclusiones obtenidas de diversas investigaciones,para dar a entender la realidad de la adhesión en dentina y despertar una actitud restauradora diferente más allá del empl...

  20. Aprovechamiento de escorias blancas (LFS) y negras (EAFS) de acería eléctrica en la estabilización de suelos y en capas de firmes de caminos rurales

    OpenAIRE

    Ortega López, Vanesa

    2012-01-01

    El trabajo que recoge la presente Tesis Doctoral estudia la idoneidad de un aprovechamiento integral de las escorias blancas de horno de cuchara (LFS) y de las escorias negras de horno eléctrico de arco (EAFS) en la estabilización de suelos arcillosos de mala calidad y en la formación de las capas del firme de caminos rurales. Para conseguir las propiedades resistentes adecuadas en terrenos naturales arcillosos sobre los que se construyen obras civiles, es preciso mezclarlos con materiale...

  1. Valor del grosor de la capa de fibras nerviosas de la retina medido mediante tomografía de coherencia óptica como marcador de daño neuroaxonal en la esclerosis múltiple

    OpenAIRE

    López Lizcano, Ruth María

    2012-01-01

    Estudio del valor del grosor de la Capa de Fibras Nerviosas de la Retina (CFNR) a lo largo de un año como marcador de daño neuroaxonal en pacientes con distintos estadios de Esclerosis Múltiple (EM): pacientes con síndrome clínico aislado (CIS) que es el estadio más inicial de enfermedad desmielinizante, pacientes con esclerosis múltiple remitente-recurrente (EMRR) y pacientes con esclerosis múltiple primaria-progresiva (EMPP) frente a sujetos sanos. Estudio de las posibles correlaciones exis...

  2. Valor diagnóstico y pronóstico de la evaluación de la capa de fibras nerviosas de la retina en la esclerosis múltiple

    OpenAIRE

    Herrero Latorre, Raquel; Polo Llorens, Vicente; Frezzotti, Pablo; García Martín, Elena

    2013-01-01

    Introducción: El tema principal de las cuatro publicaciones internacionales que componen esta tesis doctoral se centra en el estudio de la capa de fibras nerviosas de la retina en pacientes con esclerosis múltiple como método para mejorar y acelerar el proceso diagnóstico así como el seguimiento y la monitorización de esta enfermedad. Material y Métodos: Se realizó un estudio observacional y prospectivo donde se incluyeron 150 sujetos con esclerosis múltiple y 150 sujetos sanos. El protoc...

  3. Evaluación del efecto de la administración intravítrea de ranibizumab sobre el grosor de la capa de fibras nerviosas de la retina

    OpenAIRE

    Ruiz Calvo, Aurora

    2013-01-01

    El glaucoma y la degeneración macular asociada a la edad son las dos causas más frecuentes de ceguera irreversible en los países desarrollados. En el glaucoma, se produce una pérdida progresiva en la capa de fibras nerviosas de la retina que se traduce en una pérdida progresiva de campo visual y que en fases avanzadas puede conducir a la ceguera. En la degeneración macular asociada a la edad de tipo exudativo, la proliferación de neovasos en el área macular y la consiguiente exudación y sangr...

  4. Efecto de las heterogeneidades superficiales de las aleaciones de aluminio sobre el crecimiento y propiedades de las capas anódicas

    Directory of Open Access Journals (Sweden)

    Bartolomé, M. J.

    2007-08-01

    Full Text Available In the present work, X-ray photoelectron spectroscopy (XPS is used to study sealed and unsealed anodic coatings obtained on pure-Al and on Al-Cu, Al-Mg-Si and Al-Mg alloys. In general, the sealing process is seen to produce a significant increase in the O/Al ratio in the anodic coatings. This increase is more considerable with the Al-Cu and Al-Mg alloys than with the pure Al and the Al-Mg-Si alloy, perhaps due to the greater porosity of the coatings obtained on the former. An attempt is made to establish possible relationships between anodic film characteristics and surface heterogeneities, which also act in the phase prior to anodising. According to the results of this work, these heterogeneities affect the degree of dissolution of the metallic substrate during the anodising operation.

    En el presente trabajo se estudian, mediante el análisis XPS (espectroscopia fotoelectrónica de rayos-X, los recubrimientos de anodizado, sellados y sin sellar, obtenidos sobre Al-puro y aleaciones de Al-Cu, Al-Mg-Si y Al-Mg. En general, se observa un aumento significativo en las relaciones O/Al en el recubrimiento como resultado del proceso de sellado. En el caso de las aleaciones de Al-Cu y Al-Mg, se ha observado también un significativo aumento de la relación O/Al respecto al Al-puro y la aleación Al-Mg-Si, que puede estar asociado a una mayor porosidad de los recubrimientos obtenidos sobre las primeras. Se ha intentado así mismo establecer posibles relaciones entre las características de las capas anódicas y las heterogeneidades superficiales que también han actuado en la fase previa al anodizado. Según los resultados de este trabajo, estas mismas heterogeneidades afectan el grado de disolución del substrato metálico durante la operación de anodizado.

  5. Applicability of the International Classification of Functioning, Disability and Health (ICF for evaluation of children with cerebral palsy: a systematic review

    Directory of Open Access Journals (Sweden)

    Lílian de Fátima Dornelas

    2014-12-01

    Full Text Available Objective: To examine and synthesize the knowledge available in the literature on the instruments used in the perspective of functionality in children with cerebral palsy (CP, and to review the literature evaluating the instruments used for the implementation of the International Classification of Functioning, Disability and Health (ICF in children with CP. Method: The search was conducted in the electronic databases Google Scholar, PubMed, Lilacs and Medline, for articles published between January 2006 and December 2012, using the following keywords: cerebral palsy, child and assessment, combined with ICF. Ten articles were selected for analysis according to pre-established criteria. Results: The authors proposed tools that could standardize the assessment for classification of the components “Structure and function of the body”, “Activities and Participation” and “Environmental Factors”, proposing instruments such as Gross Motor Function Measure (GMFM, Pediatric Evaluation of Disability Inventory (PEDI, Goal Attainment Scaling (GAS, Manual Ability Classification System (MACS, Gross Motor Function Classification System (GMFCS, Physicians Rating Scale (PRS, Vineland Adaptive Behavior Scale (VABS, Pediatric Functional Independence Measure (Wee FIM, Gillette Functional Assessment Questionnaire (FAQ, Pediatric Quality of Life Inventory (PedsQL, Pediatric Outcomes Data Collection Instrument (PODCI, Gillette Gait Index (GGI, Energy Expenditure Index (EEI, and Vécu et Santé Perçue de l’Adolescent (VSP-A. Conclusion: The domains “Structure and function of the body” and “Activities and Participation” are often classified according to ICF in children with CP, and they present a variety of instrumentation for applicability of classification.

  6. Micromorfología de la capa híbrida de dos sistemas adhesivos: Análisis al MET Hibrid layer micromorphology of two adhesive systems: TEM analysis

    Directory of Open Access Journals (Sweden)

    V. Valenzuela Aránguiz

    2012-06-01

    Full Text Available Numerosos estudios evidencian que existen diferencias micromorfológicas entre los sistemas adhesivos monocomponentes y autograbantes. Con el objetivo de comparar la micromorfología de la Capa Híbrida de ambos sistemas, mediante observación al microscopio electrónico de transmisión (MET, se prepararon cavidades en seis premolares en dentina de mediana profundidad. A tres se les aplicó un sistema convencional monocomponente, y en tres se utilizó un sistema adhesivo autograbante. La capa híbrida formada por el sistema autograbante presentó un patrón regular, más delgado y homogéneo que la formada por el sistema adhesivo convencional. Los grosores promedio de esta estructura fueron de 1 μm y 2 μm respectivamente.Numerous studies show differences in micromorfological aspects between self-etchings and conventional adhesive systems. Dentin cavities were performed on 6 premolars to compare Micromorphology of the hybrid layer between both systems. One three of them self-etching system was applied, on the other three, the monocomponent conventional system. The hybrid layer formed by the self-etching system showed a regular pattern, thinner and more homogenous than the one formed by the conventional system. The average thickness of the structure was 1 ìm and 2 ìm respectively.

  7. Comportamiento a fatiga térmica de la capa de anclaje de nuevas barreras térmicas cerámicas obtenidas mediante proyección por plasma atmosférico

    Directory of Open Access Journals (Sweden)

    Pablo Carpio

    2016-05-01

    Full Text Available El desarrollo de nuevos materiales cerámicos para aplicarlos en recubrimientos protectores frente a la temperatura, también conocidos como barreras térmicas (Thermal Barrier Coatings o TBC, es de gran interés para muchos sectores, entre los que destacan las industrias de generación de energía, aeronáutica y automovilística.  En este trabajo se realizó un estudio del comportamiento a fatiga térmica, centrado en la respuesta de uno de los componentes que constituyen una TBC: la capa de anclaje. Los distintos componentes de la TBC fueron depositados mediante la técnica de proyección térmica por plasma atmosférico (Atmospheric Plasma Spraying o APS. Se estudió la microestructura y la composición de la capa de anclaje a lo largo de los ciclos térmicos de estudio.

  8. Analysis of the world swimming competitive situation from 14th FINA World Championship%从第14届游泳世锦赛解析世界泳坛竞争格局

    Institute of Scientific and Technical Information of China (English)

    满晓霞; 钟炼; 耿涛

    2011-01-01

    With the methods of documentation, expert interview, video observation and mathematical statistics, it analysed the results of the 14th FINA World Championships. The results showed that the gold medals have distributed in more countries such as Asian and European nowadays except the US swimmers, this made the situation more competitive. The old world swimming pattern has been broken and replaced by a new one: the United States and Australia were two leading swimming countries, but now, only the U.S. still maintained the leading position; the European countries are rising rapidly; the Asian swimming situation is unsteady. Due to the banned use of high - tech swimwear, the frequency of breaking the world record reduced. The Chinese swimming has made a greater progress and the men' s team had some breakthrough. The authors suggested that during the preparation for London Olympic Games, the Chinese swimming team should keep an eye on Britain and France and other European countries as well as the United States, and also consider the reasons why the Australian swimming performance decline, so as to explore a new training mode, which suits the Chinese swimmers the most.%通过文献资料、专家访谈、录像观察及数理统计等方法对2011年第14届上海游泳世锦赛成绩进行对比分析,管窥当前世界泳坛竞争格局。结果表明:金牌分布更为广泛,美国金牌被亚欧分流,泳坛竞争更加激烈;美国与澳大利亚两强争霸的世界泳坛格局已经消失,取而代之的是美国霸主地位稳固,欧洲诸强迅速崛起,亚洲泳坛动荡的新格局。高科技泳衣禁用后,世界纪录刷新速度放缓;中国游泳进步较大,男队成绩有所突破。明年伦敦奥运会,中国游泳除了关注传统强队美国之外,英国和法国等欧洲国家也需要格外注意。

  9. SIMULATION OF NEAR-SURFACE LAYER OF THE COLOMBIAN PACIFIC OCEAN

    Directory of Open Access Journals (Sweden)

    Karlin Lev

    2005-08-01

    Full Text Available Este artículo muestra los resultados obtenidos en el estudio de la estructura fina termohalina de la capa sub-superficial realizado en la Cuenca del Pacífico colombiano. Se formularon modelos matemáticos para diferentes regímenes de capas sub-superficiales. Basado en tres estaciones se realizó un análisis horario de información meteorológica, variación de espesor, temperatura y salinidad de la capa fina. Las leyes de formación de la estructura fina termohalina para la capa sub-superficial en la Cuenca del Pacífico colombiano están relacionadas con convección nocturna, mezcla viento-ondas, absorción de energía radiante y precipitación.

  10. Design and fabrication of a CH/Al dual-layer perturbation target for hydrodynamic instability experiments in ICF

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Jun [Shanghai Key Laboratory of Special Artificial Microstructure Materials and Technology, School of Physics Science and Engineering, Tongji University, Shanghai 200092 (China); Xie, Zhiyong [Shanghai Institute of Laser Plasma, Shanghai 201800 (China); Du, Ai [Shanghai Key Laboratory of Special Artificial Microstructure Materials and Technology, School of Physics Science and Engineering, Tongji University, Shanghai 200092 (China); Ye, Junjian [Shanghai Institute of Laser Plasma, Shanghai 201800 (China); Zhang, Zhihua; Shen, Jun [Shanghai Key Laboratory of Special Artificial Microstructure Materials and Technology, School of Physics Science and Engineering, Tongji University, Shanghai 200092 (China); Zhou, Bin, E-mail: zhoubin863@tongji.edu.cn [Shanghai Key Laboratory of Special Artificial Microstructure Materials and Technology, School of Physics Science and Engineering, Tongji University, Shanghai 200092 (China)

    2014-04-15

    Highlights: • Sinusoidal perturbed Al foil was prepared by single-point diamond turning. • Perturbed Al foil was measured by surface profiler and white light interferometer. • Perturbed Al foil and CH layer adhered with each other via a hot-press process. • Parameters and cross-section of the CH–Al perturbation target was characterized. - Abstract: A polystyrene (CH)/aluminum (Al) dual-layer perturbation target for hydrodynamic instability experiments in inertial confinement fusion (ICF) was designed and fabricated. The target was composed of a perturbed 40 μm Al foil and a CH layer. The detailed fabrication method consisted of four steps. The 40 μm Al foil was first prepared by roll and polish process; the perturbation patterns were then introduced on the surface of the Al foil by the single-point diamond turning (SPDT) technology; the CH layer was prepared via a simple method which called spin-coating process; finally, the CH layer was directly coated on the perturbation surface of Al foil by a hot-press process to avoid the use of a sticker and to eliminate the gaps between the CH layer and the Al foil. The parameters of the target, such as the perturbation wavelength (T) and perturbation amplitude (A), were characterized by a QC-5000 tool microscope, an alpha-step 500 surface profiler and a NT1100 white light interferometer. The results showed that T and A of the target were about 52 μm and 7.34 μm, respectively. Thickness of the Al foil (H1), thickness of the CH layer (H2), and cross-section of the dual-layer target were characterized by a QC-5000 tool microscope and a scanning electron microscope (SEM). H1 and H2 were about 40 μm and 15 μm, respectively, the cross-sectional photographs of the target showed that the CH layer and the Al foil adhered perfectly with each other.

  11. Interaction of a self-focused laser beam with a DT fusion target in a plasma-loaded cone-guided ICF scheme

    Science.gov (United States)

    Saedjalil, N.; Mehrangiz, M.; Jafari, S.; Ghasemizad, A.

    2016-06-01

    In this paper, the interaction of a self-focused laser beam with a DT fusion target in a plasma-loaded cone-guided ICF scheme has been presented. We propose here to merge a plasma-loaded cone with the precompressed DT target in order to strongly focus the incident laser beam on the core to improve the fusion gain. The WKB approximation is used to derive a differential equation that governs the evolution of beamwidth of the incident laser beam with the distance of propagation in the plasma medium. The effects of initial plasma and laser parameters, such as initial plasma electron temperature, initial radius of the laser beam, initial laser beam intensity and plasma density, on self-focusing and defocusing of the Gaussian laser beam have been studied. Numerical results indicate that with increasing the plasma frequency (or plasma density) in the cone, the laser beam will be self-focused noticeably, while for a thinner laser beam (with small radius), it will diverge as propagate in the cone. By evaluating the energy deposition of the relativistic electron ignitors in the fuel, the importance of electron transportation in the cone-attached shell was demonstrated. Moreover, by lessening the least energy needed for ignition, the electrons coupling with the pellet enhances. Therefore, it increases the fusion efficiency. In this scheme, with employing a plasma-loaded cone, the fusion process improves without needing an ultrahigh-intensity laser beam in a conventional ICF.

  12. Determinants of school activity performance in children with cerebral palsy: a multidimensional approach using the ICF-CY as a framework.

    Science.gov (United States)

    Huang, Chien-Yu; Tseng, Mei-Hui; Chen, Kuan-Lin; Shieh, Jeng-Yi; Lu, Lu

    2013-11-01

    This study aimed to identify the determinants of activity performance in children with cerebral palsy (CP) in school by considering factors from the entire scope of the International Classification of Functioning, Disability, and Health for Child and Youth (ICF-CY). A sample of 167 school-aged children with CP and their caregivers were recruited in the study. Activity performance in school settings was assessed with part 3 of the School Functional Assessment - Chinese version, which divides activity performance into performance of physical activities and cognitive/behavioral activities. Possible determinants were collected according to all dimensions of the ICF-CY. Multiple regression analyses showed that the determinants of performance of physical activities were receiving speech therapy in school, diplegia, having a domestic helper, and severity of gross and fine motor impairments, explaining 83% of the total variance; the determinants of performance of cognitive/behavioral activities were intellectual impairment, prosocial behavior, having an assistant in school, educational placement, severity of fine motor impairment, accounting for 73% of the total variance. Results of the study provide clinicians a holistic understanding of factors influencing school activity performance, and enable clinicians to make appropriate evaluations and interventions targeted at the determinants to enhance children's activity performance in school.

  13. Punção Aspirativa por Agulha Fina Orientada por Ultra-Sonografia em Lesões Não-palpáveis Fine Needle Aspiration Cytology Guided by Ultrasound in Nonpalpable Lesions

    Directory of Open Access Journals (Sweden)

    Cláudio Kemp

    2001-06-01

    Full Text Available Objetivo: correlacionar os achados citológicos obtidos por punção com agulha fina dirigida pela ultra-sonografia de lesões não-palpáveis da mama, císticas ou sólidas, os aspectos ultra-sonográficos e os respectivos resultados histopatológicos das lesões que foram submetidas a cirurgia. Métodos: foram analisadas 617 lesões não-palpáveis visualizadas ao ultra-som. Realizou-se a punção aspirativa por agulha fina (PAAF orientada pela ultra-sonografia, com análise citológica do material, diferenciando-as em cistos ou nódulos sólidos. Estes tiveram seu resultado citológico confrontado com o resultado histopatológico, nos casos em que foi realizada a biópsia cirúrgica. Resultados: das 617 lesões não-palpáveis, 471 eram cistos, sendo 451 cistos simples que apresentaram citologia negativa em todos os casos e 20 casos foram considerados cistos complexos. Destes, 3 (15% tiveram resultado citológico positivo ou suspeito e em 2 casos confirmou-se malignidade. Dos 105 nódulos sólidos, 63 apresentaram citologia negativa, sendo 59 concordantes com a biópsia e houve 4 casos (0,3% de resultado falso-negativo pela citologia. Todos, porém, apresentavam discordância entre imagem e citologia. Em 14 nódulos sólidos (13%, a citologia foi suspeita e, destes, 5 foram diagnosticados como carcinoma. Em outros 14 (13%, o material foi insatisfatório e 1 era carcinoma. Em 51 casos, o tríplice diagnóstico foi concordante e optou-se por seguimento clínico. Conclusão: a análise citológica do material dos cistos mamários simples é desnecessária, porém quando são complexos, a citologia é imperativa. Nas lesões sólidas não-palpáveis, é fundamental a correlação da citologia com o aspecto ultra-sonográfico e mamográfico; caso sejam discordantes, deve-se sempre prosseguir a investigação da lesão.Purpose: to determine the relationship between fine needle aspiration cytology guided by ultrasound of nonpalpable breast lesions

  14. Modification of porosity in the catalyst layer of membrane electrode assemblies using pore-forming agents; Modificacion de la porosidad en la capa catalitica de ensambles membrana-electrodo empleando agentes formadores de poros

    Energy Technology Data Exchange (ETDEWEB)

    Flores Hernandez, J. Roberto [Instituto de Investigaciones Electricas Cuernavaca, Morelos (Mexico)] e-mail: jrflores@iie.org.mx; Reyes, Brenda [UNAM. Facultad de Quimica, Mexico D.F. (Mexico); Barbosa P., Romeli [Centro de Investigacion en Energia, UNAM, Temixco, Morelos (Mexico); Cano Castillo, Ulises; Albarran, Lorena [Instituto de Investigaciones Electricas Cuernavaca, Morelos (Mexico)

    2009-09-15

    Membrane electrode assemblies (MEA) are the most important part of PEM fuel cells since their interface results in the electrochemical reactions that make the generation of electricity possible. The MEA is composed of a proton exchange membrane, both sides of which are impregnated with a catalyst layer, normally of carbon-supported platinum. Depending on the technique used for its fabrication (atomization, serigraphy, brush methods, chemical reduction, etc.), the properties of the MEA can be different in terms of porosity, distribution of the catalyst, thickness and structure of the catalyst layer, and the quality of the union between the catalyst layer and the membrane, etc. Currently, the porosity of the electrodes is generated by isopropanol evaporation (solvent used in the dye) during the fabrication process conducted in the Instituto de Investigaciones Electricas (IIE). This document presents the results obtained from adding a porous agent to the catalytic dye base composition used in the fabrication of MEA at the IIE. [Spanish] Los Ensambles Membrana-Electrodo (MEA's) son la parte mas importante en las celdas de combustibles tipo PEM, ya que en su interfaz se llevan a cabo las reacciones electroquimicas que hacen posible la generacion de electricidad. El MEA esta compuesto de una membrana de intercambio protonico a la cual se le impregna en ambos lados una capa catalitica normalmente de platino soportado en carbon. Dependiendo de la tecnica empleada en su fabricacion (atomizado, serigrafia, brocha, reduccion quimica, etc.), las propiedades del MEA pueden ser diferentes en cuanto a porosidad, distribucion del catalizador, grosor y estructura de la capa catalitica, asi como la calidad de la union entre la capa catalizadora y la membrana, etc. Actualmente, la porosidad de los electrodos es generada por la evaporacion del isopropanol (solvente utilizado en la tinta) durante el proceso de fabricacion que se realiza en el Instituto de Investigaciones

  15. MASA TOTAL Y CONTENIDO DE NUTRIENTES EN RAÍCES FINAS DE ECOSISTEMAS FORESTALES (Pinus patula Schltdl y Cham Cupressus lusitanica Mill y Quercus humboldtii Bonpl. DE PIEDRAS BLANCAS, ANTIOQUIA-COLOMBIA TOTAL FINE ROOT MASS AND NUTRIENT CONTENT IN FOREST ECOSYSTEMS (Pinus patula Schltdl and Cham Cupressus lusitanica Mill and Quercus humboldtii Bonpl. FROM PIEDRAS BLANCAS, ANTIOQUIA-COLOMBIA

    Directory of Open Access Journals (Sweden)

    Luis Hernán Barreto Sánchez

    2005-12-01

    Full Text Available En la región de Piedras Blancas, Antioquia - Colombia, se realizó un muestreo de raíces finas (£ 5 mm en tres parcelas permanentes establecidas en bosques de pino pátula (Pinus patula Schltdl y Cham, ciprés (Cupressus lusitanica Mill y roble (Quercus humboldtii Bonpl. a diferentes profundidades: 0-30, 30-50 y 50- 80 cm, con el fin de determinar la masa de raíces, y la concentración y contenido de nutrientes en cada cobertura vegetal. La masa de raíces finas disminuyó rápidamente a medida que aumentaba la profundidad, encontrándose en la parcela de ciprés el 83 % de las raíces en los primeros 30 cm de profundidad, en pino pátula el 75 % y en roble el 68 %. Los elementos con mayor participación en las raíces finas fueron calcio y potasio, siendo el primero de ellos mucho mayor en la cobertura de ciprés con respecto a las parcelas restantes, seguido en abundancia del potasio, a excepción de la parcela de roble en donde la concentración de un oligoelemento como Fe, fue incluso superior a la de calcio. Los elementos Ca, Mg, K, P, Mn, Cu y Zn acumulados en las raíces finas, hasta los 80 cm de profundidad, fueron superiores en la cobertura de ciprés, con la única excepción de Fe, que fue superior en la parcela de roble. En las parcelas de pino pátula y ciprés, el patrón de abundancia siguió la secuencia decreciente Ca > K Mg > Fe > P. En este trabajo se pretendió resaltar la importancia de las raíces finas y la concentración de los elementos, en los ecosistemas forestales naturales y plantados y su relación con el ciclo de nutrientes. Para ello, la aproximación metodológica comprendió la masa total de raíces, esto es raíces vivas y muertas en conjunto.In the Piedras Blancas region, Antioquia-Colombia, a sampling of fine roots (£ 5 mm was conducted in three permanent plots established in forest ecosystems of pine (Pinus patula Schltdl, cypress (Cupressus lusitanica Mill and oak (Quercus humboldtii Bonpl., at

  16. A utilidade da citologia por punção com agulha fina aliada a imunofenotipagem no diagnóstico dos linfomas não-Hodgkin Diagnosis of non-Hodgkin's lymphoma combining immunophenotyping and fine needle aspiration

    Directory of Open Access Journals (Sweden)

    Flávia P. S. Costa

    2005-03-01

    Full Text Available A classificação para linfomas não-Hodgkin (LNH proposta pela Organização Mundial da Saúde (OMS enfatiza a importância do imunofenótipo para o diagnóstico. O objetivo deste estudo foi avaliar a utilidade da citologia combinada a citometria de fluxo para o diagnóstico de LNH, utilizando um painel de anticorpos monoclonais e estudo do ciclo celular. O material foi obtido através de aspiração de linfonodos por agulha fina de 78 pacientes. O painel de anticorpos monoclonais para análise em citometria de fluxo foi o seguinte: CD19/CD10, CD20/CD5, CD23, CD38/CD7, CD3/CD4, CD3/CD8, kappa/lambda. O diagnóstico final foi confirmado pela histologia convencional, considerada gold standard. Em 85% dos casos a citologia associada a imunofenotipagem e porcentagem de células em fase S permitiram um diagnóstico correto. Nos demais casos foi possível diferenciar linfomas B ou T e estimar grau de agressividade. O painel, embora pequeno, foi suficiente exceto para os anaplásicos e subclassificação dos linfomas T. Nestes casos, a morfologia foi mais importante que imunofenótipo, sendo este seguro apenas para linfomas linfoblásticos. A fração de fase S mostrou-se importante para diferenciar linfomas indolentes e de alto grau. Concluímos que esta técnica é uma boa alternativa para o diagnóstico de linfomas não-Hodgkin. Permite um diagnóstico rápido, menos invasivo, podendo ser repetida quando necessário, agilizando o tratamento.The WHO classification of non-Hodgkin's lymphoma stresses the importance of the immunophenotype for diagnosis. The aim of our study was to evaluate the use of cytology together with flow cytometric examination using a panel of monoclonal antibodies including DNA S phase analysis. Material was obtained from lymph node aspiration of 78 patients. The panel for flow cytometric analysis comprised: CD19/CD10, CD20/CD5, CD23, CD3/CD4, CD3/CD8, CD38/CD7, kappa/lambda. The final diagnosis was confirmed by lymph node

  17. Teller Medal Lecture IFSA2001: Problems and solutions in the design and analysis of early laser driven high energy density and ICF target physics experiments (IFSA 2001)

    Science.gov (United States)

    Rosen, Mordecai D.

    2016-10-01

    The high energy density (HED) and inertial confinement fusion (ICF) physics community relies on increasingly sophisticated high power laser driven experiments to advance the field. We review early work in the design and analysis of such experiments, and discuss the problems encountered. By finding solutions to those problems we put the field on firmer ground, allowing the community to develop it to the exciting stage it is in today. Specific examples include: drive and preheat in complex hohlraum geometries with the complicating effects of sample motion; and issues in the successful design of laboratory soft x-ray lasers and in the invention of methods to reduce the required optical laser driver energy by several orders of magnitude.

  18. Motor training programs of arm and hand in patients with MS according to different levels of the ICF: a systematic review

    Directory of Open Access Journals (Sweden)

    Spooren Annemie IF

    2012-07-01

    Full Text Available Abstract Background The upper extremity plays an important role in daily functioning of patients with Multiple Sclerosis (MS and strongly influences their quality of life. However, an explicit overview of arm-hand training programs is lacking. The present review aims to investigate the training components and the outcome of motor training programs for arm and hand in MS. Methods A computerized systematic literature search in 5 databases (PubMed, CINAHL, EMBASE, PEDro and Cochrane was performed using the following Mesh terms: Multiple Sclerosis, Rehabilitation, Physical Education and Training, Exercise, Patient-Centered Care, Upper Extremity, Activities of Daily Living, Motor Skills, Motor Activity, Intervention Studies and Clinical Trial. The methodological quality of the selected articles was scored with the Van Tulder Checklist. A descriptive analyses was performed using the PICO principle, including scoring of training components with the calculation of Hedges’g effect sizes. Results Eleven studies were eligible (mean Van Tulder-score = 10.82(SD2.96. Most studies reported a specific improvement in arm hand performance at the ICF level that was trained at. The mean number of training components was 5.5(SD2.8 and a significant correlation (r = 0.67; p  Conclusion Motor training programs (both at the ICF body function and activity level have shown to improve arm and hand performance in MS in which the value of the training specificity was emphasized. To optimize upper extremity training in MS the component ‘client-centred’ and ‘exercise progression’ may be important. Furthermore, given the importance attributed to the components ‘distribution based practice’, ‘feedback’ and ‘random practice’ in previous research in stroke patients, the use of these components in arm hand training should be explored in future research.

  19. Comercio e intercambio de cerámicas finas en la Bética (ss. I-II d. C.: reflexiones generales en torno a la economía altoimperial al hilo del análisis del ejemplo isturgitano

    Directory of Open Access Journals (Sweden)

    Pablo RUIZ MONTES

    2013-06-01

    Full Text Available El análisis de un caso concreto, el de la comercialización de la producción de cerámicas finas de los talleres alfareros de Los Villares de Andújar (Jaén, antigua Isturgi, ofrece la oportunidad para reflexionar sobre diversos aspectos relativos al intercambio y circulación de este tipo de bienes coincidiendo con los años de mayor bonanza económica y social en la Bética; el análisis de la naturaleza de la economía romana, de las formas y alcance que adquiere el comercio en cuestión (distribución local-regional y a larga distancia y su caracterización esencial, así como otros elementos colaterales al fenómeno (valor, gusto, consumidores..., han centrado nuestra atención. Todo ello permite dibujar una situación de excepcional dinamismo económico del que la producción y comercio de vajillas cerámicas locales, en especial la sigillata, es parte, pero también consecuencia. El proceso, intensificado desde Claudio I gracias al desarrollo de la red de comunicaciones y los transportes, la mayor demanda de bienes y un moderado crecimiento demográfico, propicia la aparición de nuevos estándares en la producción de cerámicas finas locales béticas, hasta entonces dominada aún por las tradiciones autóctonas y la desestructurada producción de cerámicas tipo Peñaflor.

  20. 上海游泳世锦赛世界泳坛竞争格局变化特征分析%Analysis of the Evolvement of Competition Situation of World Swimming from the 14th FINA World Championships SHANGHAI 2011

    Institute of Scientific and Technical Information of China (English)

    洪家云; 宋静敏; 房殿生

    2011-01-01

    对2011年第14届世界游泳锦标赛的成绩进行分析,并与第13届世锦赛和北京奥运会游泳项目进行比较.结果显示:因禁止运动员穿高科技泳衣进行比赛,上海世锦赛成为破纪录较少的世界游泳大赛,且获得奖牌的国家比上届少;美国依然是世界泳坛的霸主;中国男子项目首次获得奥运项目的冠军并打破世界纪录,亚洲三强中国女子项目称雄,女子混合泳、仰泳、蝶泳和接力项目上取得优异成绩;日本男子整体实力依然强劲.%In our report, the method of literature review, mathematical statistics and logical induction, were used to analyze the 14th FINA World Championships results, and with the 13th FINA World Championships and the Beijing Olympic Games swimming events for comparison. The results showed that because of prohibiting the athletes to wear high tech swimsuit, Shanghai World Championships had become the least in the world record breaking swimming competition, and the gold medal were more less distributed than that of last; United States remained the worlds' dominant swimming, and Chinese man project obtained champions and broke the world record at first time, Chinese woman project achieved excellent results in the medley, backstroke, butterfly and relay events; Japanese man project still maintained its traditional advantage.

  1. Análise do desgaste de capas de eletrodos de solda ponto e sua influência na qualidade da soldagem de chapas automotivas galvanizadas Assessment of spot welding electrodes wearing and their influence on the quality of welded automotive galvanized sheets

    Directory of Open Access Journals (Sweden)

    Hideraldo Luiz Osório Branco

    2012-12-01

    Full Text Available As capas de eletrodos utilizados na soldagem por resistência por pontos (solda ponto sofrem desgaste durante a soldagem de chapas galvanizadas, devido ao elevado aquecimento e pressão na sua superfície. Neste trabalho avaliou-se a influência do desgaste sofrido por diferentes tipos de capas de eletrodos sobre as propriedades mecânicas e acabamento do ponto de solda. Observou-se que o desgaste varia de acordo com a capacidade de retenção de dureza a quente, e que a superfície das capas sofre intensa reação com o zinco da chapa galvanizada. Como conseqüência do desgaste das capas de eletrodo, o ponto de solda sofre redução progressiva do seu diâmetro (o que pode comprometer sua integridade estrutural, além de uma piora significativa do seu acabamento superficial.Electrodes caps used in RSW wear out during the welding of galvanized sheets, caused by the high heating and pressure. In this work was evaluated the wearing influence of different kinds of electrodes caps over mechanical properties and surface finish of the spot weld. Was also observed that the wearing varies according to the hot hardness retention capacity, and the electrode caps surface suffer an intense reaction with zinc from the galvanized sheet. As a result of the electrodes caps wearing, the spot weld diameter is progressively reduced, that can compromise it's structural integrity.

  2. A systematic review of outcomes assessed in randomized controlled trials of surgical interventions for carpal tunnel syndrome using the International Classification of Functioning, Disability and Health (ICF as a reference tool

    Directory of Open Access Journals (Sweden)

    Leite José

    2006-12-01

    Full Text Available Abstract Background A wide range of outcomes have been assessed in trials of interventions for carpal tunnel syndrome (CTS, however there appears to be little consensus on what constitutes the most relevant outcomes. The purpose of this systematic review was to identify the outcomes assessed in randomized clinical trials of surgical interventions for CTS and to compare these to the concepts contained in the International Classification of Functioning, Disability and Health (ICF. Methods The bibliographic databases Medline, AMED and CINAHL were searched for randomized controlled trials of surgical treatment for CTS. The outcomes assessed in these trials were identified, classified and linked to the different domains of the ICF. Results Twenty-eight studies were retrieved which met the inclusion criteria. The most frequently assessed outcomes were self-reported symptom resolution, grip or pinch strength and return to work. The majority of outcome measures employed assessed impairment of body function and body structure and a small number of studies used measures of activity and participation. Conclusion The ICF provides a useful framework for identifying the concepts contained in outcome measures employed to date in trials of surgical intervention for CTS and may help in the selection of the most appropriate domains to be assessed, especially where studies are designed to capture the impact of the intervention at individual and societal level. Comparison of results from different studies and meta-analysis would be facilitated through the use of a core set of standardised outcome measures which cross all domains of the ICF. Further work on developing consensus on such a core set is needed.

  3. Effect of thermal treatment temperature on plated ICF glass targets%热处理温度对化学镀磁性ICF玻璃靶丸特性的影响

    Institute of Scientific and Technical Information of China (English)

    杨文彬; 周元林; 卢忠远; 戴亚堂; 卢苇

    2009-01-01

    在300,700和1 000 ℃温度下,对化学镀Ni-P合金涂层后的磁性ICF玻璃靶丸进行热处理,通过X射线衍射仪(XRD)、扫描电子显微镜(SEM)和振动样品磁强计(VSM)对热处理后化学镀ICF玻璃靶丸的结构、形貌和磁性能进行了表征.结果表明:化学镀ICF玻璃靶丸经过热处理后,Ni-P涂层晶化为晶态合金层,涂层的组成颗粒直径和磁性能随着热处理温度的升高而不断增加,可望用于磁悬浮实验研究.%Plated ICF glass targets were treated under 300 ℃,700 ℃ and 1 000 ℃ for one hour,respectively.Structure,morphology and magnetic property of the plated ICF glass targets were characterized by X-ray diffraction(XRD),scanning electron microscopy(SEM) and vibrating sample magnetometry(VSM).The results show that the Ni-P plating on the surface of the ICF glass targets will be crystallized after the targets are thermally treated.The diameter of the crystalline grains and the corresponding magnetic parameters of the Ni-P plating increases with increasing the thermal treatment temperature.The treated ICF glass targets could be used in research of magnetic suspension experiment.

  4. Study of high gain spherical shell ICF targets containing uniform layers of liquid deuterium tritium fuel. A numericial model for analyzing thermal layering of liquid mixtures of hydrogen isotopes inside a spherical inertial confinement fusion target: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, E.M.; Kim, Kyekyoon [Lawrence Livermore National Lab., CA (United States)

    1994-05-01

    A numerical model has been developed to describe the thermally induced behavior of a liquid layer of hydrogen isotopes inside a spherical Inertial Confinement Fusion (ICF) target and to calculate the far-field temperature gradient which will sustain a uniform liquid layer. This method is much faster than the trial-and-error method previously employed. The governing equations are the equations of continuity, momentum, energy, mass diffusion-convection, and conservation of the individual isotopic species. Ordinary and thermal diffusion equations for the diffusion of fluxes of the species are included. These coupled equations are solved by a finite-difference method using upwind schemes, variable mesh, and rigorous boundary conditions. The solution methodology unique to the present problem is discussed in detail. in particular, the significance of the surface tension gradient driven flows (also called Marangoni flows) in forming uniform liquid layers inside ICF targets is demonstrated. Using the theoretical model, the values of the externally applied thermal gradients that give rise to uniform liquid layers of hydrogen inside a cryogenic spherical-shell ICF target are calculated, and the results compared with the existing experimental data.

  5. 应用于ICF实验的软X射线平面镜反射率%Investigation on reflectance of soft X-ray mirror used in ICF experiments

    Institute of Scientific and Technical Information of China (English)

    郭志英; 易荣清; 杜华冰; 何小安; 郑雷; 赵屹东

    2012-01-01

    Soft X-ray mirror used in inertial confinement fusion (ICF) experiments have been preformed at the 4B7B beam-line of Beijing Synchrotron Radiation Facility (BSRF). The main factors influencing the mirror reflectance were investigated and confirmed to be the contamination and the installation angle of mirrors. Simulation of the reflectance of contamination mirrors confirms the contamination is the carbon and oxygen from oil in ICF experiments. The contamination can be effectively removed by a radio-frequency glow discharge treatment for mirrors. The reflectance of mirrors which is improved after cleaning process is found to be in good agreement with the calculation results.%在北京同步辐射装置上,通过对应用于惯性约束聚变(ICF)实验的平面镜反射率的进一步研究,提高了辐射温度的测量精度.进行了对软X射线平面镜反射率的测量、反射镜的清洗、反射率的模拟计算,证明影响反射率变化的主要因素是平面镜的安装角度和沾污.实验结果表明:平面镜的沾污主要来源于ICF实验中的油沾污,采用射频辉光放电清洗非常有效.

  6. 卫生政策的政治分析及一种辅助政治分析软件的应用%Application of CAPA software in health policy reform process

    Institute of Scientific and Technical Information of China (English)

    杨善发; 程鑫; 宋娟

    2004-01-01

    国外卫生政策研究表明,卫生政策过程不仅要经过技术分析和伦理分析,更要经过政治分析,而后者往往被政策设计与分析人员所忽视.为了提高卫生政策的政治可行性,哈佛大学公共卫生学院卫生政策专家Michael Reich教授等开发了名为"Policy Maker'"的"计算机辅助政治分析(CAPA)"软件,该软件通过5个步骤对卫生政策政治可行性进行分析,其广泛应用表明,虽然有一定的风险和限制,但它为驾驭卫生政策的政治复杂性提供了一个很有针对性、实用性及有效性的工具,推动了卫生政策技术的一场革命.

  7. Observation of asymmetric implosions in indirect-drive ICF associated with changes in laser beam-hohlraum coupling and relevance to mix experiments.

    Science.gov (United States)

    Turner, R. E.; Amendt, P. A.; Landen, O. L.; Wallace, R. J.; Thorp, K.; Pien, G.

    2004-11-01

    Indirect drive ICF experiments were performed on the Omega laser at LLE, both with and without distributed polarization rotators (DPR) in the laser beams. The hohlraums were irradiated with a three-cone beam geometry, experimentally adjusted to produce high-yield implosions with no DPRs installed. X-ray images of the cores of these implosions showed a small but tolerable P2 asymmetry. Similar experiments with DPRs installed produced lower yields, and x-ray images of the imploded cores showed substantially increased P2 asymmetries, suggesting that the shallow-angle cone of beams, which transits through the longest length of plasma and along the shallowest density gradients, had substantially increased absorption compared to the no-DPR case. We will show high magnification (nearly 100x) x-ray images of the cores, along with fusion neutron data. For capsules driven with good symmetry, we show the neutron yield results from capsules whose surfaces have been deliberately roughened by a measured amount, in order to compare to mix models in simulations.

  8. Laser-Plasma Instability Control Using TPulse fixed vs Imax fixed Spike Trains of Uneven Duration and Delay: The Path to Green ICF Using STUD Pulses

    Science.gov (United States)

    Afeyan, Bedros; Hüller, Stefan; Meezan, Nathan; Hammer, Jim; Heebner, John

    2016-10-01

    We have studied the behavior of laser-plasma instabilities (LPI) as a function of seed noise (varied over seven orders of magnitude) and Rosenbluth gain exponent at the average intensity (varied over a decade) for structured laser beams with and without STUD pulse mitigation. We will show that for each section of the NIF ICF pulse, there are preferred configurations of STUD pulses, whether they be fixed duration of fixed peak intensity, so that maximum use is made of STUD pulse flexibility for LPI control. The duty cycle, hot spot scrambling rate, and cutting a hot spot into pieces (by switching the lasers on and off on the ps time scale), are the three main tools. We explore a variety of phase transitions in reflectivity behavior and in the amplification profile of plasma perturbations. We compare cases where amplification bursts are reinforced coherently or are healed, lead to brush fires or are tamed. The STUD pulse program is best suited for Green light implementation since Green offers higher bandwidth, more energy, and higher damage thresholds. We plan to test these ideas on the Jupiter Laser Facility at LLNL at the pair of 200J lasers level next. Work supported by a Grant from the DOE NNSA-FES Joint Program on HEDP and by LLNL.

  9. Optical Mixing in the Strong Coupling Regime: A New Method of Beam Conditioning at Hohlraum LEH and Direct Drive ICF Coronal Plasmas

    Science.gov (United States)

    Mardirian, Marine; Afeyan, Bedros; Huller, Stefan; Montgomery, David; Froula, Dustin; Kirkwood, Robert

    2012-10-01

    We will present theoretical and computational results on Brillouin interactions between two beams in co-, counter-, and orthogonal propagation geometries. The beams will be structured (with speckle patterns), the plasma will have inhomogeneous flow including the Mach -1 surface. As the growth rate of the instability surpasses the natural frequency of the ion wave, the strong coupling regime (SCR) is reached, where reactive quasi-modes with intensity dependent frequency shifts result. This is especially true in laser hot spots. We trace the consequences of operations in this regime with different damping rates on the ion acoustic waves. We consider convective and absolute instabilities as well as the design of experiments which could examine these new regimes of instability behavior with new 10 psec time resolved diagnostics. Whether well enough conditioned beams can result after 10's or 100's of pairwise crossings in direct and indirect drive ICF configurations, and whether SRS can thus be strongly suppressed downstream, remains to be demonstrated. But the prospects exist for such new paths to instability control in a staged manner before STUD pulses are implemented.-

  10. O diagnóstico do carcinoma metastático de coróide pela biópsia aspirativa com agulha fina (BAAF: relato de caso The diagnosis of metastatic carcinoma of the choroid using fine-needle aspiration biopsy (FNAB: case report

    Directory of Open Access Journals (Sweden)

    Zélia Maria da Silva Corrêa

    2003-01-01

    Full Text Available OBJETIVO: Relatar o caso de um paciente com carcinoma de pulmão cuja primeira metástase detectada foi em coróide e a abordagem diagnóstica deste caso. MÉTODOS: Um homem de 35 anos, em tratamento devido a uma condensação pulmonar isolada, referiu baixa da acuidade visual súbita, dor, secreção e olho vermelho (olho direito há 10 dias. Ao exame oftalmológico foi detectada a presença de descolamento não regmatogênico de retina e múltiplos focos tumorais em coróide confirmado pela ultra-sonografia ocular diagnóstica. Foi sugerida biópsia aspirativa com agulha fina (BAAF para diagnosticar possível doença metastática. A biópsia aspirativa com agulha fina foi realizada sob anestesia peribulbar e sedação. A rota escolhida foi transvítrea através de esclerotomia a 4 mm do limbo. O procedimento foi monitorado via oftalmoscopia binocular indireta. Foram obtidas 2 amostras de focos tumorais diferentes. Após a biópsia aspirativa com agulha fina, as amostras foram encaminhadas para processamento, fixação e coloração pelos métodos Papanicolaou e hematoxilina-eosina. RESULTADOS: A citologia confirmou a suspeita de múltiplos focos metastáticos coroídeos. Os aspirados ocular e pulmonar revelaram ser de mesma origem devido à reação positiva com pan-citoqueratina (AE1/AE3. O paciente evoluiu para óbito 4 meses após diagnóstico citológico de carcinoma metastático ocular. CONCLUSÕES: A biópsia aspirativa com agulha fina foi eficiente em diagnosticar e correlacionar a citologia ocular com o tumor primário por métodos citoquímicos neste caso. A biópsia aspirativa com agulha fina ainda deve ser usada em casos selecionados e pesquisas futuras serão necessárias para que este procedimento diagnóstico seja considerado padrão em oftalmologia.PURPOSE: To report a case of a patient with lung carcinoma in which the first detected metastasis was to the choroid, how it was diagnosed and confirmed. METHODS: A 35 year-old white

  11. Relación entre las partículas finas (PM 2.5 y respirables PM 10 en la ciudad de Medellín Relation between fine particles (PM 2.5 and breathable particles (PM 10 in Medellin city

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Echeverri Londoño

    2008-01-01

    Full Text Available En este trabajo se presenta parte de los resultados del proyecto 'Patologías respiratorias en niños preescolares y su relación con la contaminación atmosférica de Medellín', realizado por la Universidad de Medellín y la Universidad CES para la Secretaria de Salud de Medellín dentro del contrato 4700026668 de 2006. Se realizaron mediciones simultáneas de partículas finas (PM2.5 y respirables (PM10 durante el período de febrero a octubre de 2007 en varios sitios de la ciudad de Medellín, capital del departamento de Antioquia, habitada aproximadamente por 2’250.000 personas. Los resultados del análisis muestran, en la mayoría de los casos, una correlación positiva y lineal entre los dos parámetros. La relación (PM2.5/PM10 promedio para los sitios o zonas bajo consideración en este estudio fue de aproximadamente 0.67, valor bastante considerable que hace pensar que probablemente se puede cumplir con la norma anual para PM10, pero no para PM2.5. Los resultados obtenidos identifican las partículas finas como uno de los principales problemas de contaminación en la ciudad de Medellín.This article shows part of the results from the project called: 'Respiratory pathologies in pre-school children and their relation to atmospheric contamination in Medellin,' carried out by Universidad de Medellin and Universidad CES for Medellin Health Secretariat according to contract No. 4700026668, year 2006. Simultaneous measurements of fine particles (PM2.5 and breathable particles (PM10 were made from February to October, 2007 in several sites of Medellin, the capital city of Antioquia State, where about 2,250,000 inhabitants live. In almost all cases, analysis results show a positive and linear correlation between both parameters. Average ratio (PM2.5/PM10 for sites and zones tested in this study was 0.67 approximately, which is a very meaningful value, what makes us think that annual norm for PM10 can probably be accomplished, but not the one

  12. Comportamiento parabólico del crecimiento de capas boradas en los aceros Y8A y X12M // Parabolic behavior of boriding layers growth in Y8A and X12M steels

    Directory of Open Access Journals (Sweden)

    C. Figueroa Hernández

    1999-01-01

    Full Text Available Se determina la influencia que tienen los principales parámetros tecnológicos del borado en el crecimiento de las capas y secorrobora el cumplimiento de la ley parabólica para predecir este comportamiento en los aceros Y8A y X12M.El proceso de borado se aplica en una mezcla de carburo de silicio y bórax (70 y 30 % a la temperatura de 850, 900 y 950 oCdurante un tiempo de 2, 4 y 6 horas. Como variable dependiente se seleccionó la profundidad del recubrimiento, a partir de lacual se obtuvieron los coeficientes del crecimiento parabólico y la energía de activación en función de la temperatura, el tiempodel proceso y el tipo de acero.La caracterización metalográfica reveló la presencia de la fase Fe2BPalabras claves: Borado, recubrimiento superf icial , t ecnología de recubrimiento.__________________________________________________________________________AbstractIt was determined the influence of the main technological parameters of the boriding process, and a mathematical model thatallows to predict this conduct on the steels Y8A and X12M steels was obtained.The boriding process is applied in a mixture of silicon carbide and borax (70 and 30% at 850, 900 and 950 oC temperatureduring a period of time 2, 4 and 6 hours. As an independent variable the depth of the coat was selected.It was obtained the parabolic growth coefficients, and the activation energy according to temperature, time and the chemicalcomposition of steel.Metallografic analysis reveals the presence of Fe2B phase.Key words: Boriding process, superf icial coat , coat technology.

  13. CAPA模式对COPD病人使用BiPAP呼吸机早期依从性的影响%Influence of CAPA mode on early compliance of COPD patients using BiPAP ventilator

    Institute of Scientific and Technical Information of China (English)

    万群芳; 彭曦; 朱晶; 何芳; 蒋丽

    2012-01-01

    [目的]探讨提高慢性阻塞性肺疾病(COPD)病人使用双水平正压通气(BiPAP)呼吸机早期依从性的客观有效的干预方式.[方法]将68例需要使用BiPAP呼吸机治疗的慢性阻塞性肺疾病急性期(AECOPD)伴轻、中度呼吸性酸中毒的Ⅱ型呼吸衰竭病人随机分为对照组和试验组,在带机初,对照组直接使用BiPAP模式,并逐渐上调吸气压力,试验组由低压力的持续正压通气(CAPA)模式逐渐过渡至BiPAP模式再逐渐上调吸气压力.监测两组病人带机后2h的动脉血气,同时调查两组病人带机的舒适度及12h内的依从性.[结果]两组舒适度及依从性比较差异有统计学意义(P<0.05或P<0.01),血气分析比较差异无统计学意义(P>0.05).[结论]从低压力CAPA模式逐渐过渡至治疗压力的BiPAP模式可提高病人使用BiPAP呼吸机的依从性.

  14. Fine-root production in two secondary forest sites with distinct ages in Eastern Amazon Produção de raízes finas em dois sítios de floresta secundária com diferentes idades na Amazônia Oriental

    Directory of Open Access Journals (Sweden)

    Tâmara Thaiz Santana Lima

    2012-03-01

    Full Text Available The objective of this work was to assess the fine-root (≤ 2 mm diameter production dynamics of two forest regrowths at different ages. Fine-root production was monitored by the ingrowth core method in one 18-year-old site (2 ha and one 10-year-old site (0.5 ha, both localized in the Apeú region, Northern Pará State, Brazil. The sites were abandoned after successive shifting cultivation, beginning in 1940. Monthly production of live fine-root was similar between sites and was influenced by rainfall seasonality, with higher production during the dry season than the wet season for mass and length. However, mortality in terms of mass was higher in the 10-year-old site than in the 18-year-old site. The seasonality influenced mortality only in the 18-year old site following the pattern observed for live fine-root. The influence seasonal on mortality in terms of length was different between sites, with higher mortality during the wet season in the 10-year-old site and higher mortality during the dry season in the 18-year-old site. Specific root length was higher during the wet season and at the 10-year-old site. Fine-root production was not influenced by the chronosequence of the sites studied, probably fine-root production may have already stabilized in the sites or it depended more on climate and soil conditions. The production of fine-roots mass and length were indicators that generally showed the same pattern.O objetivo deste trabalho foi avaliar a dinâmica de produção de raízes finas (diâmetro ≤ 2 mm em duas áreas de floresta secundária com diferentes idades. A produção de raízes finas foi monitorada utilizando a técnica de ingrowth core em um sítio com 18 anos de idade (2 ha e um outro sítio com 10 anos de idade (0,5 ha, localizados na região de Apeú, nordeste do Estado do Pará. Os sítios foram abandonados depois de sucessivos ciclos agrícolas, iniciados em 1940. A produção mensal de raízes vivas foi semelhante entre os

  15. Influência da energia de soldagem em uniões de lâminas finas através de laser pulsado de Nd:YAG Effect of the heat input on pulsed Nd:YAG laser welding of thin foil

    Directory of Open Access Journals (Sweden)

    Vicente A. Ventrella

    2010-12-01

    Full Text Available A soldagem laser vem sendo utilizada como um importante processo de manufatura. Ela pode ser utilizada tanto no modo contínuo quanto no modo pulsado. No processo onde se utiliza laser pulsado é possível realizar soldas de costura em lâminas finas, através da sobreposição dos pulsos. Nesse caso a velocidade de soldagem é definida pela taxa de sobreposição, taxa de repetição e diâmetro do pulso. A soldagem de sobreposição de lâminas finas apresenta problemas típicos como distorção excessiva da junta soldada, falta de contato entre as lâminas a serem soldadas (presença de um gap de ar, perfuração da junta e presença de altos níveis de tensões residuais. O processo de laser pulsado é preferido em relação ao processo por laser contínuo, pois ele possibilita um melhor controle da energia de soldagem. O presente trabalho estudou a influência da energia do pulso, no caso processo de soldagem laser Nd:YAG, na soldagem de lâminas finas ( 100µm de aço inoxidável austenítico AISI 316L, utilizado no revestimento de sensores (que trabalham em ambiente corrosivo da indústria sucroalcooleira. Utilizou-se energia de pulso de 1,0 a 2,25 Joules, com incremento de 0,25 Joules e largura temporal de 4 ms. As soldas foram realizadas com proteção gasosa de argônio. Foram realizadas análises macrográficas das juntas soldadas, através de secções transversais das mesmas e, ensaios de microdureza Vickers e ensaios de tração. Os resultados obtidos mostraram que o controle da energia do pulso, em processo de soldagem por laser de lâminas finas é de fundamental importância para a geração de juntas soldadas com boas propriedades mecânicas e livres de descontinuidades. O limite de resistência da junta soldada aumentou no início e depois sofreu um pequeno decréscimo em função do aumento da energia do pulso. O processo mostrou-se muito sensível à presença de gap entre as lâminas.Laser beam welding has been used widely

  16. ICF 理论框架为基础的农村脑瘫患儿实用家庭康复模式探讨%Exploration on the ICF-based practical family rehabilitation model for rural children with cerebral palsy

    Institute of Scientific and Technical Information of China (English)

    张明武; 黄艳植; 蒙爱珍; 陈国治; 谭玮玮; 黄亮量; 蒋锦生; 罗寀宾; 林盈盈

    2013-01-01

    目的:探讨适合于居住在农村的脑瘫患儿的实用家庭康复模式。方法以国际功能、残疾和健康分类( ICF)理论框架为基础,通过家长集中培训、专业技术人员入户指导和电话回访三种形式,指导家长在家庭对50例农村脑瘫患儿进行为期1年的家庭康复。结果50例患儿的运动能力有明显改善,生活自理能力与社会适应能力也得到了提高,康复总有效率达88%。结论以ICF理论框架为基础的农村脑瘫患儿家庭康复模式,能让家长日常工作与患儿康复训练两不误,家长依从性高,患儿的康复训练能得到长期坚持,并取得了良好的效果,值得推广。%Objective To investigate the practical family rehabilitation model suitable for rural children with cerebral palsy .Methods Based on the theoretical framework of International Classification of Functioning , Disability and Health( ICF) , parents were guided to conduct one-year family rehabilitation for 50 rural children with cerebral palsy at home through concentrated training for parents , guidance by professional and technical personnel entering their homes as well as telephone interview .Results The sports ability self-care ability of daily living and social a-daptability of the 50 children with cerebral palsy were improved with a total rehabilitation efficiency rate of 88%. Conclusion The ICF-based family rehabilitation model for rural children with cerebral palsy allows parents to do their daily work with children rehabilitation training , parents′compliance is high and the rehabilitation of children can get long-term adherence with good results , thus it is worthy of promotion .

  17. The relation between foF2 and ICF during the solar eclipse%日食期间foF2与ICF的相关性分析

    Institute of Scientific and Technical Information of China (English)

    张添益

    2001-01-01

    本文初步分析了1995年10月24日日食期间,F2层临界频率(foF2)和高频干扰重心频率(ICF)之间的相关性较差的原因.认为高频干扰重心频率ICF不仅受foF2的影响,还可能受D层吸收等因素影响.在探讨ICF与foF2的关系时,应综合加以考虑.

  18. Research on the Criterion-related Validity of Comprehensive ICF Core Sets for Stroke%脑卒中ICF核心分类量表综合版的效标关联效度研究①

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    Objective To analyse the criterion-related validity of comprehensive ICF Core Sets for stroke. Methods Comparison of con-cepts of items among SF-36, Barthel index, Mini-mental State Examination, WHO quality of life-BREF, WHO Disability Assessment ScaleⅡ and Comprehensive ICF Core Sets for stroke had been conducted using the linking rules established by Cieza and Stucki. Field test had been conducted for 93 patients with stroke with the above 6 scales. Results 16 body function items and 27 activities and participation items matched with items of the selected functioning measurement scales (0.4ICF core sets for stroke has good criterion-related validity.%  目的分析研究脑卒中ICF核心分类量表(ICF Core Sets)综合版的效标关联效度。方法根据联系规则将健康调查简表(SF-36量表)、Barthel指数、简易精神状态检查(MMSE)、世界卫生组织生存质量测量简表(WHOQOL-BREF)、世界卫生组织《残疾评定量表》(WHO-DASⅡ)中项目的概念与脑卒中ICF核心分类量表综合版中项目的概念作定性研究,确定测量项目内容的关联性。在此基础上选择上述6个量表对93例脑卒中患者进行临床测量研究和相关分析。结果脑卒中ICF核心分类量表综合版中16个身体功能项目及27个活动和参与项目与本研究所选择的测试量表中的项目内容相关(0.4

  19. Formación de capa híbrida al cementar postes metálicos y de fibra de vidrio en dientes tratados endodónticamente Hybrid layer formation using metal post and fiber post into endodontically trated canal roots

    OpenAIRE

    V. Valenzuela Aránguiz; X. Zamorano Pino; S. Wagner Hitschfeld; J.R. Tapia Silva

    2010-01-01

    Se evaluó al microscopio electrónico de barrido (MEB) la efectividad de la adhesión lograda dentro de conductos tratados utilizando dos sistemas adhesivos, uno de fotocurado (Single Bond) y otro dual (Prime & Bond NT + Self-Cure Activator) y dos sistemas de postes (fibra de vidrio y metálicos). El objetivo fue evaluar la formación de capa híbrida y tags de resina al interior de los conductos radiculares. Método: Doce piezas dentarias fueron preparadas para recibir un poste. Se dividieron en d...

  20. 财政部部长助理李勇率团参加亚太会计师联合会理事会会议%CICPA delegation led by Li Yong, Assistant Minister of MOF, attended the CAPA EXCOM

    Institute of Scientific and Technical Information of China (English)

    国际部

    2001-01-01

    @@ 5月27日-29日亚太会计师联合会(CAPA)在马来西亚吉隆坡召开第57次理事会会议.财政部部长助理兼中国注册会计师协会秘书长李勇、副秘书长李爽和有关人员代表中国注册会计师协会参加了此次吾事会会议.

  1. Effective thermal conductivity of the hair coat of Holstein cows in a tropical environment Condutividade térmica efetiva da capa de pelame de vacas Holandesas em ambiente tropical

    Directory of Open Access Journals (Sweden)

    Alex Sandro Campos Maia

    2009-11-01

    Full Text Available The objective of the present study was to assess the effective thermal conductivity of the hair coat (k ef, mW.m-1.K-1 of Holstein cows in a tropical environment, as related to conduction and radiation in the absence of free convection. The average k ef was 49.72 mW.m-1.K-1, about twice the conductivity of the air (26 mW.m-1.K-1 and much less than that of the hair fibres (260 mW.m-1.K-1. The low k ef values were attributed mainly to the small cross area of individual hairs, ρef/ρf (17.2% and 21.3% for black and white hairs, respectively. White coats were denser, with longer hairs and significantly higher k ef (53.15 mW.m-1.K-1 than that of the black hairs (49.25 mW.m-1.K-1. The heritability coefficient of the effective thermal conductivity was calculated as h²=0.18 the possibility was discussed of selecting cattle for increased heat transfer through the hair coat.O objetivo neste trabalho foi estudar a condutividade térmica efetiva do pelame (k ef, mW.m-1.K-1 atribuída à condução e radiação na ausência de convecção livre no pelame de vacas Holandesas manejadas em ambiente tropical. A média para condutividade térmica efetiva do pelame foi 49,72 mW.m-1.K-1, quase o dobro da condutividade térmica do ar (26 mW.m-1.K-1 e bem inferior à do pelo (260 mW.m-1.K-1. O baixo valor observado para condutividade térmica efetiva do pelame deve-se principalmente à pequena área ocupada por pelos (ρef/ρf, que foi somente 17,2% e 21,3% nos pelames preto e branco, respectivamente. O pelame branco foi mais denso e formado por pelos mais compridos, logo sua condutividade térmica efetiva (53,15 mW.m-1.K-1 foi significativamente maior que a do pelame preto (49,25 mW.m-1.K-1. A herdabilidade para a condutividade térmica efetiva é de 0,18, o que indica a possibilidade de se fazer seleção para elevar a transferência de calor através da capa.

  2. Estudios de series temporales de energía solar UV-B de 305 nm y espesor de la capa de ozono estratosférico en Arica, norte de Chile Study of time series for 305 nm solar energy UV-B and stratospheric ozone layer thickness Arica in the north of Chile

    Directory of Open Access Journals (Sweden)

    Miguel Rivas

    2011-08-01

    Full Text Available En este trabajo se muestran los resultados del análisis de las series temporales de la energía solar medida a nivel del suelo, en la banda de 305 nm, y el espesor de la capa de ozono estratosférico. El rasgo más importante es la independencia de los valores de energía a nivel del suelo respecto de la variabilidad de corto periodo de la capa de ozono, siendo probablemente efectos meteorológicos locales los que llevan el mayor peso de la varianza.In this paper, the results obtained by analyzing time series of ground level energy of the solar radiation in the 305 nm band and stratospheric ozone layer thickness are shown. The most relevant feature found is the independence of the variability of the ground level energy with respect to the short period variations of the ozone layer, being the meteorological local effects those which more heavily affect the variability.

  3. Punção aspirativa por agulha fina no diagnóstico de linfadenopatias e tumores sólidos em crianças e adolescentes Fine needle aspiration biopsy in the diagnosis of lymphadenopathies and solid tumors in children and adolescents

    Directory of Open Access Journals (Sweden)

    Wallace Acioli Freire de Gois

    2008-02-01

    Full Text Available OBJETIVO: Avaliar a importância diagnóstica da punção aspirativa por agulha fina (PAAF em crianças e adolescentes portadores de linfadenopatias e tumores sólidos. MÉTODOS: Análise retrospectiva dos pacientes com idade igual ou inferior a 18 anos, atendidos no Centro de Pediatria Cirúrgica do Hospital Universitário de Brasília, Universidade de Brasília, no período de julho de 2000 a julho de 2005. Foram calculados: sensibilidade, especificidade, precisão (acurácia diagnóstica, valor preditivo positivo e valor preditivo negativo. RESULTADOS: Em 50 pacientes estudados, os resultados da PAAF mostraram sensibilidade de 90,9%; especificidade de 100%, precisão diagnóstica de 95% e valores preditivos positivo e negativo de 100% e 90%, respectivamente. CONCLUSÃO: Em nossa experiência, a PAAF é um método preciso, simples e seguro, útil no diagnóstico de linfadenopatias e tumores sólidos em crianças e adolescentes.BACKGROUND: To evaluate the diagnostic value of the fine needle aspiration biopsy in children and adolescents with solid tumors or lymphadenopathy. METHODS: 18 years old or less patients were observed since July 2000 to July 2005. We observed: sensibility, specificity, diagnostic accuracy and predictive value. RESULTS: In 50 studied patients the fine needle aspiration biopsy we found 90.9% sensibility, 100% specificity, 95% diagnostic accuracy, 100% positive predictive value and 90% negative predictive value. CONCLUSION: The fine needle aspiration biopsy is a easy, safe and accurate diagnostic method for solid tumors and lymphadenopathies.

  4. Evaluación del potencial bactericida de los extractos de bacterias ácido lácticas sobre el crecimiento in vitro de E. coli, Salmonella sp. y Listeria monocytogenes.

    Directory of Open Access Journals (Sweden)

    Luz Adriana Gutierrez Ramírez

    2005-01-01

    La evaluación de la naturaleza del extracto se realizó por cromatografía en capa fina comprobando que posiblemente una gran parte de la acción bactericida del extracto de L. plantarum se debe a la acción de péptidos.

  5. Síntesis de mono y diitaconatos de alquilo y arilo

    Directory of Open Access Journals (Sweden)

    Francisco J. Sánchez

    2011-10-01

    Full Text Available Se presenta una técnica para la síntesis en laboratorio de mono y diitaconatos y la separación de los mismos por extracción selectiva con solventes orgánicos. La pureza de los productos se determina por cromatografía en capa fina y por espectroscopia infrarroja.

  6. Comparison and physical interpretation of MCNP and TART neutron and {gamma} Monte Carlo shielding calculations for a heavy-ion ICF system

    Energy Technology Data Exchange (ETDEWEB)

    Mainardi, E. E-mail: enrico@nuc.berkeley.edu; Premuda, F.; Lee, E

    2004-01-01

    Inertial confinement fusion (ICF) aims to induce implosions of D-T pellets to obtain a extremely dense and hot plasma with lasers or heavy-ion beams. For heavy-ion fusion (HIF), recent research has focused on 'liquid-protected' designs that allow highly compact target chambers. In the design of a reactor such as HYLIFE-II [Fus. Techol. 25 (1984); HYLIFE-II Progress Report, UCID-21816, 4.82-100], the liquid used is a molten salt made of F{sup 10}, Li{sup 6}, Li{sup 7}, Be{sup 9} (called flibe). Flibe allows the final-focus magnets to be closer to the target, which helps to reduce the focus spot size and in turn the size of the driver, with a large reduction of the cost of HIF electricity. Consequently the superconducting coils of the magnets closer to the D-T neutron source will potentially suffer higher damage though they can stand only a certain amount of energy deposited before quenching. This work has been primarily focusing on verifying that total energy deposited by fusion neutrons and induced {gamma} rays remain under such limit values and the final purpose is the optimization of the shielding of the magnetic lens system from the points of view of the geometrical configuration and of the physical nature of the materials adopted. The system is analyzed in terms of six geometrical models going from simplified up to much more realistic representations of a system of 192 beam lines, each focused by six magnets. A 3-D transport calculation of the radiation penetrating through ducts, that takes into account the complexity of the system, requires Monte Carlo methods. The technical nature of the design problem and the methodology followed were presented in a previous paper [Nucl. Instr. and Meth. A 464 (2001) 410] by summarizing briefly the results for the deposited energy distribution on the six focal magnets of a beam line. Now a comparison of the performances of the two codes TART98 [TART98: A Coupled Neutron-Photon 3-D Combinational Geometry Monte Carlo

  7. ICF微靶装配体图像清晰度评价方法%Image Definition Evaluation Method of ICF Micro-target Assembly

    Institute of Scientific and Technical Information of China (English)

    聂凯; 刘文耀; 王晋疆

    2014-01-01

    During the process of evaluating ICF micro-target image with the current image definition evaluation function, owing to the changes in image contrast of different components of micro-target, the evaluation function may lose its ideal curve characteristics easily. This may not only result in the decrease of focus accuracy but also, in some cases, the failure of the entire focusing process. Based on the analysis of the causes for the blurring defocused image, we discovered that the primary reason for defocused image was structural distortion. With the characteristic of Zernike moment of descri-bing the image structure in mind, we propose a new function for evaluating the image definition of micro-target. The new evaluation function is consisted of Zernike moments weighting of different steps, and it is realized through the evaluation of image contrast for micro-targets of different defini-tions by regulating the weight coefficient. We confirm that the new evaluation function maintains the ideal curve characteristics during the process of evaluating the micro-target images compared to the current evaluation function. In the condition of low contrast, however, the new approach holds a distinct advantage in terms of sensitivity and noise immunity.%现有图像清晰度评价函数在对ICF微靶装配体图像的评价过程中,由于不同零件图像对比度的变化,评价函数极易失去其理想曲线特性,导致聚焦精度降低甚至调焦过程失败。针对这一问题,在分析离焦图像模糊原因的基础上,得出离焦图像究其本质为图像结构变化失真。利用Zernike矩具有描述图像结构特征这一特性,提出一种新的针对微靶装配体图像的清晰度评价函数。评价函数由图像不同阶Zernike矩的线性组合构成,通过调节权重系数来实现微靶装配体不同零件图像的清晰度评价。实验结果表明:相较于现有的评价函数,新的评价函数在对微靶

  8. Framework, Measurement, and Social Support of Intellectual Disability Based on ICF%基于ICF的智力残疾模式、测量方法及社会支持系统研究

    Institute of Scientific and Technical Information of China (English)

    邱卓英; 李欣; 刘冯铂; 李毓秋

    2016-01-01

    目的探讨基于ICF的智力残疾的定义、结构与术语体系,理论架构、社会支持与服务模式,以及智力残疾的测量方法。方法采用ICF的理论与方法以及美国智力与发展障碍协会(AAIDD)相关理论与方法进行分析。结果智力残疾是以智力功能损伤和适应性行为有显著活动受限为特征的障碍。适应性行为主要表现在概念性、社交性以及实践性适应技能方面,智力残疾发生于18周岁之前。本文还提出了基于ICF的智力残疾服务与支持架构、主要领域与内容,以及基于新的智力残疾定义的测量方法。结论基于ICF的智力残疾理论架构与方法、服务与支持系统以及测量方法符合现代残疾理论架构,为智力残疾的测量、康复、教育与社会服务提供了理论和方法。%Objective To explore the definition, structure, terminology, framework, and models of social support and services, and mea-surement of intellectual disability based ICF approach. Methods The ICF approach and definition and approach proposed by American Asso-ciation on Intellectual and Developmental Disabilities (AAIDD) were adopted. Results The characteristics of intellectual disability are sig-nificant limitations in both intellectual functioning and adaptive behavior as expressed in conceptual, social, and practical adaptive skills, and onset before 18 years old. The framework, domains and contents of services and support for intelligence disability were proposed, as well as the updated measurement of intelligence disability based on new framework and definition. Conclusion The new framework of intel-ligence disability, system of service and support, and measurement are in accordance with the bio-psycho-social model of disability of ICF. The new paradigm will provide framework and tool of measurement, rehabilitation, education, and social services for people with intelli-gence disability.

  9. Formación de capa híbrida al cementar postes metálicos y de fibra de vidrio en dientes tratados endodónticamente Hybrid layer formation using metal post and fiber post into endodontically trated canal roots

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    V. Valenzuela Aránguiz

    2010-04-01

    Full Text Available Se evaluó al microscopio electrónico de barrido (MEB la efectividad de la adhesión lograda dentro de conductos tratados utilizando dos sistemas adhesivos, uno de fotocurado (Single Bond y otro dual (Prime & Bond NT + Self-Cure Activator y dos sistemas de postes (fibra de vidrio y metálicos. El objetivo fue evaluar la formación de capa híbrida y tags de resina al interior de los conductos radiculares. Método: Doce piezas dentarias fueron preparadas para recibir un poste. Se dividieron en dos grupos de 6 piezas, a cada uno de los cuales se les colocó un tipo de poste. Ambos grupos fueron subdivididos en dos, aplicándoles distintos adhesivos, la resina de cementación RelyX ARC y el poste correspondiente. Las muestras fueron cortadas longitudinalmente y preparadas para la observación al MEB. Resultados: No se evidenciaron diferencias en cuanto al espesor de la capa híbrida entre los grupos. Se concluye que la capa híbrida y tags de resina formados dentro de los conductos utilizando ambos sistemas de postes y diferentes sistemas adhesivos, no son satisfactorios.The goal of this study was to evaluate the adhesive effectiveness attained in root canals endodontically treated with a scanning electronic microscope (SEM. We used two adhesive systems (Single Bond and Prime&Bond NT + Self Cure Activator and two post systems (fiberglass and metallic. The main objective was to evaluate the hybrid layer and resin tag formation inside each root canal. Twelve teeth were used, which were prepared for receiving the post. The teeth were divided into two groups of 6 pieces each. Each group received one type of post. In turn, each group was subdivided in two (a total of 4, receiving different adhesives, the cementation resin RelyX ARC and the corresponding post. The samples were cut longitudinally and prepared to be scrutinized with the microscope. The results showed that the adhesion inside the canal roots was not reliable. No difference regarding the

  10. ICF理论框架在小儿脑性瘫痪社区家庭康复评估中的应用%Application of Framework of ICF in Community-based Rehabilitation Assessment for Children with Cerebral Palsy

    Institute of Scientific and Technical Information of China (English)

    张明武; 黄艳植; 林盈盈; 陈国治; 谭玮玮; 黄亮量; 罗寀宾; 蒙爱珍; 蒋锦生

    2014-01-01

    目的:探索以ICF理论框架为基础的小儿脑瘫社区家庭康复评估的理论架构与方法。方法根据ICF理论框架,综合多种评估工具和自编工作量表,开发评估系统。对50例农村小儿脑瘫患儿进行社区家庭康复1年。结果和结论 ICF理论框架为小儿脑瘫社区家庭康复评估提供良好的架构,为评估工具的建立与体系化提供了参考依据;根据评估结果所制定的康复计划依从性较好,取得良好的康复效果。%Objective To explore the theoretical framework and method of community-based rehabilitation assessment for children with cerebral palsy based International Classification of Functioning, Disability and Health (ICF). Methods The system of assessment of commu-nity-based rehabilitation was developed based on the theoretical framework ICF, combined with multi-tools and self-compiled work scales. The system was used for 50 rural children with cerebral palsy after 1-year of community-based rehabilitation. Results and Conclusion The system of assessment is applicable for rural community-based rehabilitation of children with cerebral palsy, with satisfactory efficacy and compliance.

  11. 基于ICF构建特殊体育教育课程体系与内容1%Building the Curriculum and Content of Special Physical Education Based on the ICF

    Institute of Scientific and Technical Information of China (English)

    金梅; 高飞; 马勇

    2014-01-01

    本研究依据《国际功能、残疾和健康分类》(ICF)的理论与方法,从身体功能和残疾问题出发,探讨适应当代社会发展需求的特殊体育教育目标、知识结构体系和课程体系,并以此为基础重新架构特殊体育教育的课程体系和内容。认为特殊体育教育的学生不仅要掌握一定数量的专业基础知识,而且要具备一定的应用能力,才能更好地为特殊需要的儿童进行各种训练、评估和干预。%This research was based on the theory and method of International Classification of Function, Disability and Health (ICF) and looked into the issues of physical function and disability. It tried to explore the purpose, knowledge structure and curriculum of special physical education that met the needs of social development and to restructure the curriculum and content of special physical education. Stu-dents of special physical education should not only master basic specialized knowledge, but also be able to practice theories, so as to better serve all kinds of children with special needs in training, assessment and intervention.

  12. Avaliação da expressão da proteína bcl-2 no carcinoma de mama: estudo em punção aspirativa por agulha fina; correlação com grau histológico em espécimes cirúrgicos correspondentes

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    Derossi Daniela Rudgeri

    2003-01-01

    Full Text Available INTRODUÇÃO: O gene bcl-2 codifica uma proteína envolvida no processo de controle da apoptose. Inicialmente descrito em linfomas e posteriormente em tecidos epiteliais, sua expressão é freqüentemente encontrada em carcinomas de mama, associada a fatores de prognóstico favorável. Como a punção aspirativa por agulha fina (PAAF tem sido utilizada como um método confiável na investigação de carcinomas de mama, acessamos a expressão de bcl-2 em material assim obtido e correlacionamos sua positividade com o grau histológico, avaliado em material cirúrgico correspondente, das respectivas pacientes, seguindo a classificação de SBR (Scarff, Bloom e Richardson. OBJETIVOS: Avaliar a expressão de bcl-2 em PAAF e correlacionar com grau histológico. METODOLOGIA: A positividade do bcl-2 foi analisada, por imunocitoquímica, em 118 casos consecutivos de PAAF e correlacionada com grau histológico em material cirúrgico correspondente, segundo classificação de SBR. RESULTADOS: A positividade para bcl-2 foi encontrada em 77 de 118 casos de PAAF (65,25% e foi inversamente proporcional ao grau histológico (84,37%, p = 0,0022. CONCLUSÃO: A expressão de bcl-2 em PAAF correlaciona-se com fator de bom prognóstico. O índice de positividade encontrado, assim como a correlação inversa com grau histológico, está de acordo com dados publicados previamente. O fácil e rápido manejo do material obtido por PAAF permite a aplicação de técnicas complementares, de maneira confiável, como demonstra este estudo. A positividade do bcl-2 correlacionada com baixo grau histológico, assim como com outros fatores de bom prognóstico, pode, no futuro, proporcionar informação preditiva e prognóstica para pacientes candidatas a tratamento quimioterápico neo-adjuvante.

  13. Punção aspirativa por agulha fina: desempenho no diagnóstico diferencial de nódulos mamários palpáveis Fine needle aspiration biopsy: performance in the differential diagnosis of palpable breast masses

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    Orlando José de Almeida

    1998-09-01

    Full Text Available Objetivo: avaliar, de forma prospectiva, o desempenho da punção aspirativa por agulha fina (PAAF no diagnóstico diferencial de nódulos mamários palpáveis. Método: avaliaram-se a sensibilidade, a especificidade, os valores preditivos e a acurácia deste teste em 102 mulheres com idade superior a 30 anos, com nódulos mamários palpáveis, atendidas na Universidade Estadual de Campinas. As punções foram realizadas por um único examinador. Resultados: o procedimento teve sensibilidade de 97%, especificidade de 87%, valor preditivo positivo de 94% e negativo de 93%. A taxa de material insuficiente ou insatisfatório foi de 16% na primeira punção, diminuindo para 2% com uma nova PAAF. Conclusões: Este teste mostrou-se altamente sensível e específico no diagnóstico diferencial de nódulos mamários palpáveis, reafirmando-se a sua grande importância na abordagem clínica de nódulos palpáveis.Purpose: to evaluate, in a prospective way, the performance of the fine needle aspiration biopsy in the differential diagnosis of palpable breast masses. Method: the sensitivity, specificity, positive and negative predictive values for this test were evaluated in 102 women with age above 30 years and a palpable breast mass, who were attended at the University of Campinas. All punctures were performed by the same examiner. Results: the procedure had a sensitivity of 97%, specificity of 87%, positive predictive value of 94% and negative predictive value of 93%. The insufficient or unsatisfactory sample rate was 16% for the first aspiration, decreasing to 2% with a new procedure. Conclusions: this test showed to be highly sensitive and specific for the differential diagnosis of palpable breast masses, reassuring its great importance for the clinical approach of palpable masses.

  14. O cérebro no imaginário social da divulgação científica das biociências : a retórica sobre a saúde e a vida nas capas da revista Mente e Cérebro

    OpenAIRE

    Anderson dos Santos Machado

    2015-01-01

    Este trabalho analisa a retórica presente nas capas da revista Mente e Cérebro, buscando repre-sentações sociais do cérebro recorrentes em revistas de divulgação científica. É um estudo de caso que descreve como o cérebro é apresentado na articula-ção simbólica que denominamos simbiose ima-gem/palavra no sentido de identificar as estratégias de convencimento a partir dos elementos simbólicos presentes nesta articulação, e não em função do va-lor de verdade discursiva. Procurou-se avaliar como...

  15. Modelo predictivo del espesor de la capa de óxido y microdureza en aluminio Al3003-B14 y Al6063-T6 anodizado usando análisis multifactorial Oxide film thickness and microhardness prediction model of Al3003-B14 and Al6063-T6 anodized aluminum using multifactorial analysis

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    Leonardo Eladio Vergara Guillén

    2011-08-01

    Full Text Available En esta investigación se modela a partir de los parámetros del proceso el espesor de la capa de óxido y la microdureza de los aluminios Al3003 y Al6063 anodizados. Para ello se realizaron estudios de la microdureza y espesor de capa de la superficie anodizada, utilizando técnicas de análisis multifactorial y diseño robusto. Se establecieron los siguientes niveles de los parámetros del proceso: temperatura [15 °C, 25 °C], tiempo [30 min; 60 min], concentración de electrolito [1,2 M; 2 M], densidad de corriente [1 Amp/dm²; 3 Amp/dm²], aluminio [Al3003,Al6063] y como variable de ruido, la deformación plástica [0%, 10%, 20%, 30%]. Se propuso un diseño fraccionado 2(7-2 mixto, con el cual se efectuó un total de 48 pruebas usando soluciones electrolíticas de ácido sulfúrico. La medición de microdureza se realizó con un indentador Vickers con carga de 400 g; el espesor de la capa de óxido se captó mediante microscopia electrónica. A los resultados se les realizó un análisis de varianza (ANOVA, para determinar los factores significativos y la robustez de los efectos. Se encontraron resultados de microdureza [HV] [85,74-308,87]; y espesor de óxido [µm] [12,82- 94,69]. Finalmente, se muestran los modelos de predicción de cada una de las respuestas en función de los factores significativos estas ecuaciones permitirán seleccionar la microdureza y espesor de la capa de óxido para cumplir los requerimientos de un producto particular mediante una selección apropiada de los parámetros del proceso.In this research, the thickness of the oxide layer and the microhardness of anodized aluminum Al3003 and Al6063 are modeled based on process parameters. To this end, studies of the microhardness and the thickness layer of the anodized surface were made, via techniques of multifactorial analysis and robust design. The following levels of the process parameters were established: temperature [15°C, 25°C], time [30min; 60min

  16. Estudio de "las capas del cabo ladrillero superior" en el cabo homónimo, mioceno inferior de la cuenca austral, tierra del fuego Study of "The Upper Cabo Ladrillero Beds" in the homonym locality, Lower Miocene of the Austral Basin, Tierra del Fuego

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    Estefanía P Tudisca

    2012-03-01

    Full Text Available En los acantilados del cabo Ladrillero, situado sobre la costa atlántica de la Isla Grande de Tierra del Fuego, afloran parte de los depósitos cuspidales que rellenan la cuenca de antepaís Austral o de Magallanes. Estos depósitos del Mioceno inferior son conocidos como "capas del Cabo Ladrillero" y "capas del Cabo San Pablo", siendo las "capas del Cabo Ladrillero superior" las analizadas en este trabajo. La zona de estudio, situada a una decena de kilómetros al norte del frente orogénico emergente (Punta Gruesa, permitió reconocer cuatro asociaciones de facies que registran depósitos gravitacionales resedimentados en un ambiente marino supra batial y una cuña deltaica progradante y somerizante hacia el noreste. Entre los rasgos más conspicuos observados en esta sucesión se destacan bancos deformados, intervalos macizos y abundantes diques clásticos, cuyo análisis estadístico indica un patrón transtensivo. Los microfósiles documentados en el área y utilizados previamente como herramienta para sostener un ambiente marino profundo provienen de niveles estratigráficos infrayacentes y corresponden a niveles de la Formación Desdémona y las capas del Cabo Ladrillero inferior, aflorantes hacia el sur de la zona de estudio. Las evidencias sedimentológicas no son concluyentes respecto de la batimetría, pero la ausencia de turbiditas clásicas, flujos hiperpícnicos, la abundancia de bancos deformados y resedimentados, restos vegetales y fragmentos de carbón son compatibles con un ambiente somero y deltaico con altas tasas de aporte y pendientes inestables antes que un ambiente marino profundo, y sugieren una historia compleja de la evolución del relleno sedimentario que no se explica meramente con los esquemas basados exclusivamente en el contenido de foraminíferos que domina en la literatura.In the cliffs of the Ladrillero cape, situated on the Atlantic coast of the Isla Grande de Tierra del Fuego, the uppermost records of the

  17. Estudio de la capa de fibras nerviosas de la retina mediante tomografía de coherencia óptica y polarimetría láser en pacientes con esclerosis múltiple: correlación con la función visual y los hallazgos de la resonancia magnética

    OpenAIRE

    Abalo Lojo, José Manuel

    2012-01-01

    Introducción: La tomografía de coherencia óptica (OCT) y la polarimetría láser (GDx) son técnicas exploratorias de la capa de fibras nerviosas de la retina (CFNR). Hipótesis: En los pacientes con EM, el posible daño estructural de la CFNR y su correspondiente alteración de la función visual sería un reflejo del daño del SNC y por lo tanto se correlacionaría con las alteraciones de la resonancia magnética (RM) y la discapacidad Material y métodos: El estudio se ha realizado con 96 paci...

  18. AS DIFERENÇAS FINAS: DE SIMMEL A LUHMANN

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    Cohn Gabriel

    1998-01-01

    Full Text Available Tendências recentes na teoria social indicam o crescimento do interesse por esquemas analíticos diferentes daqueles que se concentram na ação racional segundo um "paradigma da troca". Opõem-se, também, à distinção convencional entre "individualismo" e "holismo". O artigo procura analisar conjuntamente as contribuições de dois autores aparentemente distantes entre si (Simmel e Luhmann para esse debate.

  19. Fracciones de carbono orgánico en la capa arable: efecto de los sistemas de cultivo y fertilización nitrogenada Organic carbon fractions in the arable layer: cropping systems and nitrogen fertilization effects

    Directory of Open Access Journals (Sweden)

    Maximiliano J Eiza

    2005-07-01

    Full Text Available Nuestro objetivo fue evaluar el efecto de siete sistemas de cultivo (SC en un experimento de larga duración: pastura permanente (PP, agricultura permanente bajo siembra directa (SD (SD100 y labranza convencional (LC (LC100, rotación agricultura pastura (50%-50% del tiempo bajo SD (SD50 y LC (LC50, rotación agricultura pastura (75%-25% del tiempo bajo SD (SD75 y LC (LC75 y dos dosis de fertilización nitrogenada: 0 y 120 kg N ha-1, sobre el carbono orgánico total (COT y particulado (COP, para 0-20 cm en 1994 y para 0-5, 5-20 y 0-20 cm de profundidad en 2003. En 1994, los mayores COP y COT se asociaron a manejos con períodos agrícolas previos cortos. En 2003, se encontraron diferencias entre SC en COT en la capa de 0-5 cm de profundidad, siendo PP, LC50 y SD50 los tratamientos con mayor COT. El COP fue más alto bajo PP, LC50 y SD50 a 0-5 y 0-20 cm de profundidad. A 0-5 cm COP bajo SD fue significativamente mayor que bajo LC. A 5-20 cm de profundidad, las diferencias en COP no fueron claras entre SC aunque, tendió a disminuir con los años bajo agricultura. La fertilización determinó mayor COP a 5-20 y 0-20 cm de profundidad. Las diferencias en la variación entre 1994 y 2003 entre SC fueron significativas para COP y COT. Por otro lado, la variación relativa de COP fue más alta que la de las otras variables. Se concluye que las rotaciones cortas de agricultura-pastura, la SD y la fertilización nitrogenada mejoran el COP y el COT. Para las condiciones de este experimento, COP ha sido un indicador más sensible que COT y sería capaz de detectar los efectos de las prácticas de manejo.In the southeastern Buenos Aires Province (Argentina unsuitable combination of crop rotation and tillage systems (cropping systems, SC has reduced soil organic matter content. Our aim was to evaluate the effect of seven SC in a long term experiment (since 1976 started in 1994: permanent pasture (PP, permanent cropping under no tillage (SD (SD100 and

  20. 中文版下背痛简明ICF核心要素及其效度与信度的初步研究%A preliminary study of the brief Chinese version of the ICF core sets for low back pain and their validity and reliability

    Institute of Scientific and Technical Information of China (English)

    夏文广; 郭铁成; 郑婵娟; 华强; 余兰芬; 张阳普

    2008-01-01

    Objective To develop a brief Chinese version of the International Classification of Functioning,Disability,and Health(ICF)core sets for low back pain and to test their validity and reliability. Methods The through clinical investigation.Sixty patients with low back pain were then recruited and evaluated using the Chinese sets,the Oswestry disability index(ODI)and the Roland-Moms Disability Questionnaire(RMDQ).Thirty patients were selected randomly and examined again with the Chinese ICF core sets 2 days after the 1st evaluation to test their repeatability.Pearson correlation analysis between the ICF core sets and the other scales was conducted to test the validity of the brief ICF core sets for Chinese patients with low back pain. Results The Pearson correlation analysis revealed a significant relationship between the results with the Chinese ICF core sets and ODI and RMDQ results.The Chinese ICF core sets were also found to have good repeatability. Conclusion The brief Chinese version of the ICF core sets is reliable and valid in the evaluation of Chinese patients with low back pain.%目的 探讨中文版下背痛简明"国际功能、残疾和健康分类"(ICF)核心要素的组成,并检验其应用于下背痛患者的信度和效度.方法 参照国外ICF核心要素量表制定中文版下背痛简明ICF核心要素量表并应用于下背痛患者,确定该量表所包括的条目.同时采用中文版Oswestry功能障碍指数(ODI)和Roland-Moms功能障碍调查表(RMDQ),并结合患者自我报告、临床记录、医学检查等方法,对60例下背痛患者进行综合测评.将下背痛患者的简明ICF核心要素与中文版Oswestry功能障碍指数以及Roland-Morris功能障碍调查表评分进行相关性分析,2 d后重复测评ICF核心要素,评估其重测信度.结果 简明ICF核心要素量表的有效性测评结果显示其与ODI、RMDQ有显著相关性;ICF核心要素量表具有良好的可重复性.结论 下背痛简明ICF核心

  1. An overview and profile of the ICF's use in Brazil - a decade of history Panorama e perfil da utilização da CIF no Brasil - uma década de história

    Directory of Open Access Journals (Sweden)

    João A. Ruaro

    2012-01-01

    Full Text Available BACKGROUND: In 2001the World Health Organization (WHO adopted a classification system for understanding functioning and human disability: the International Classification of Functioning, Disability and Health (ICF. The ICF’s acceptance and use has been facilitated by the development and global consensus process, with increasing evidence about its validity. OBJECTIVES: To investigate the overview of the use of the ICF in Brazil, since its conception in 2001 until the year 2011. METHOD: We conducted an integrative literature review by searching SciELO, Lilacs, PubMed and ISI databases. To be included in the review, the study must have been published as scientific article, editorial or technical note, and had to having the participation of Brazilian researchers or have been developed in Brazil. RESULTS: One hundred and two publications were identified, but only 47 studies were included based in the inclusion criteria. Most of eligible studies were related to neurology (n=16 and orthopaedics (n=12 subdisciplines. The university that most appeared in the publications in national journals was The Universidade de São Paulo (11 and in the international journals was Universidade Federal de Minas Gerais (4. In 2003 there was only one publication; in 2010 and 2011 were 10 and 8, respectively. CONCLUSIONS: Although incipient, the use of ICF in the Brazilian scientific community is rising. There is a concentration of studies related to the locomotor system, as well as performed by universities in the southeast area of Brazil.CONTEXTUALIZAÇÃO: Em 2001, a OMS aprovou um sistema de classificação para o entendimento da funcionalidade e da incapacidade humana: a Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF. A aceitação e a utilização da CIF vêm sendo facilitadas pelo seu desenvolvimento e processo de consenso global, com crescente evidência sobre a sua validade. OBJETIVOS: Investigar o panorama do uso da CIF no Brasil

  2. An overview and profile of the ICF's use in Brazil - a decade of history Panorama e perfil da utilização da CIF no Brasil : uma década de história

    Directory of Open Access Journals (Sweden)

    João A. Ruaro

    2012-12-01

    Full Text Available BACKGROUND: In 2001the World Health Organization (WHO adopted a classification system for understanding functioning and human disability: the International Classification of Functioning, Disability and Health (ICF. The ICF’s acceptance and use has been facilitated by the development and global consensus process, with increasing evidence about its validity. OBJECTIVES: To investigate the overview of the use of the ICF in Brazil, since its conception in 2001 until the year 2011. METHOD: We conducted an integrative literature review by searching SciELO, Lilacs, PubMed and ISI databases. To be included in the review, the study must have been published as scientific article, editorial or technical note, and had to having the participation of Brazilian researchers or have been developed in Brazil. RESULTS: One hundred and two publications were identified, but only 47 studies were included based in the inclusion criteria. Most of eligible studies were related to neurology (n=16 and orthopaedics (n=12 subdisciplines. The university that most appeared in the publications in national journals was The Universidade de São Paulo (11 and in the international journals was Universidade Federal de Minas Gerais (4. In 2003 there was only one publication; in 2010 and 2011 were 10 and 8, respectively. CONCLUSIONS: Although incipient, the use of ICF in the Brazilian scientific community is rising. There is a concentration of studies related to the locomotor system, as well as performed by universities in the southeast area of Brazil.CONTEXTUALIZAÇÃO: Em 2001, a OMS aprovou um sistema de classificação para o entendimento da funcionalidade e da incapacidade humana: a Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF. A aceitação e a utilização da CIF vêm sendo facilitadas pelo seu desenvolvimento e processo de consenso global, com crescente evidência sobre a sua validade. OBJETIVOS: Investigar o panorama do uso da CIF no Brasil

  3. Designing Optical Element of Beam Splitting Illumination for Adjusting Light path in ICF%用于ICF光路调整的分光照明元件设计

    Institute of Scientific and Technical Information of China (English)

    张超; 谭建军; 黄小霞; 赵曦; 高福华

    2013-01-01

    在惯性约束核聚变激光驱动装置中,光路庞大复杂且元器件众多,为保证激光系统正常运行需对光路进行精密调节.特别是装置中的多个4F系统,需调整激光光路使其聚焦后对准焦平面滤波小孔中心,以保证激光顺利通过并实现低通滤波作用.目前实际工程中采用凹透镜背光照明的方法判断光束是否准确过孔,但该方法步骤繁琐且调整精度较低,给实际光路调整带来了极大的不便.本文基于全息原理,提出了一种简单高效的4F系统光路调整方法,通过一特殊设计的分光照明衍射光学元件,可一步实现激光聚焦过孔的判断与调整,可有效解决现有4F系统光路调整的困难.%Numerous elements and huge laser system are existed in Inertial Confine Fusion driver (ICF).It is necessary to adjust light path accurately so as to ensure that the laser system can work normally.Expecially,the 4F system in ICF plays a role of low-pass filtering,so the purpose of adjusting is to make laser pass the center of filter hole in focus plane.Currently,the method in practical engineering is to use a concave lens for splitting light illumination to judge whether the beam pass the filter hole.However,the disadvantage of this method is tedious and low precision,which is inconvenient in actual adjusting.In this paper,a simple but effective way to adjust light path in 4F system is presented based on holography theory.With a specially designed diffractive optical element for splitting light illumination,judging and adjusting laser to pass the filter hole can be easily achieving.Thus,it can solve the difficulty of existing method.

  4. Application of ICF in the Study of the Physical Healthy Promotion of Intellectual Disability in the Community%ICF在社区智力障碍者体质健康促进中的应用研究

    Institute of Scientific and Technical Information of China (English)

    王丹丹; 吴雪萍

    2016-01-01

    国际功能、残疾和健康分类(International Classification of Functioning,disability and health,ICF)是全球性的、通用性的,跨学科、跨领域的描述健康状况的分类体系.以ICF为理论基础,运用ICF的互动模式架构图对当前社区智力障碍者的身体功能和身体结构状况,以及与他们体质健康状况相关的活动参与现状和阻碍性的背景环境因素进行分析.为之后设计具有针对性的干预方案,建立健全智力障碍者健康状况的评估反馈体系,使智力障碍者的健康促进研究更科学有效.

  5. Contribution to modelization and simulation of the ablative-like Rayleigh-Taylor instabilities for ICF; Contribution a la modelisation et a la simulation des instabilites de type Rayleigh-Taylor ablatif pour la FCI

    Energy Technology Data Exchange (ETDEWEB)

    Egly, H

    2007-10-15

    This thesis deals with the dynamics of accelerated ablative front spreading in Inertial Confinement Fusion experiments. ICF is designed for the implosion of a deuterium-tritium spherical target. The outer shell, the ablator, is irradiated providing a high level pressure inside the target. During this first stage, the ablation front propagating inwards is perturbed by hydrodynamics instabilities, which can prevent the fusion reaction in the decelerated stage. We propose here a study on Rayleigh-Taylor instabilities during ablation process, in the two dimensional case. In order to obtain a numerical solution, we perform an asymptotic analysis in the limit of a high temperature ratio, between the remaining cold ablator and the hot ablated plasma. This study is divided in two steps. First, the thermo-diffusive part of the set of equations is approximated by a Hele-Shaw model, which is then perturbed by the hydrodynamics part. Using a vortex method, we have to solve the advection of a vortical sheet moving with the ablation front. We compute the numerical solution on an Eulerian mesh coupled with a marker method. The thermal part is computed by implementing the Fat Boundary Method, recently developed. The hydrodynamic part is obtained from a Finite Volume scheme. (author)

  6. Laser-Based Ultrasonic Generation in Metal Film With Nanometer Thickness Used in ICF Experiment%ICF靶用纳米厚金属薄膜中超声波的激光激励

    Institute of Scientific and Technical Information of China (English)

    王衍斌; 周建华; 余学才

    2012-01-01

    简要介绍了激光超声和干涉仪检测原理,实现了一个激光超声实验.实验中,用调Q Nd:YAG固体激光器在超薄薄膜200 nm Al/Au/Ag中激励高频超声,用迈克尔逊干涉仪对超声进行了检测,对获得的信号进行傅里叶变换,获得了激励的振动频率.3种薄膜中产生的单一频率的超声振动分别为32.36、26.17和29.39 MHz.本工作对纳米薄膜的超声检测有一定的参考和借鉴作用.%The generation and detection of laser-based ultrasound were introduced. The experiment was performed. A beam of laser with pulse width of 7 ns produced by Q switch Nd:YAG was used to irradiate Al/Au/Ag metal films with thickness of 200 nm. The signal was detected by Michael interference method and transferred by Fourier method. The ultrasonic vibration frequencies excited in the sample are 32. 36, 26. 17 and 29. 39 MHz, respectively. The work is valuable to detect nano- and micro-meter films used to ICF experiment for the future.

  7. Elaboración y aplicación de una guía didáctica de técnicas Grafoplásticas “Aprendiendo con mis Manitas” para el desarrollo de la motricidad fina, para los niños y niñas del primer año de educación general básica de la unidad educativa verbo divino, de la parroquia Veintimilla, de la ciudad de Guaranda, provincia Bolívar, período 2013- 2014.

    OpenAIRE

    2015-01-01

    El tema denominado la elaboración y aplicación de una guía didáctica de técnicas grafoplásticas “Aprendiendo con mis Manitas” para el desarrollo de la motricidad fina, para los niños y niñas del primer año de Educación General Básica de la Unidad Educativa Verbo Divino, de la Parroquia Veintimilla, de la Ciudad de Guaranda, provincia Bolívar, período 2013- 2014. Se realizó con el objetivo de demostrar que la aplicación de las diferentes técnicas grafoplásticas permitieron desarrollar en lo...

  8. “Elaboración y aplicación de una guía de técnicas lúdicas de motricidad fina “habilidades y destrezas” para desarrollar la iniciación a la Lecto - Escritura de las niñas y niños de 4-5 años de la unidad educativa “Rumiñahui” de la comunidad Chocaví central parroquia san isidro, cantón guano, provincia de Chimborazo, periodo 2013 – 2014”.

    OpenAIRE

    Palomino Pulgar, Alva Judith

    2015-01-01

    La presente investigación está orientada a satisfacer necesidades educativas referentes al desarrollo de la iniciación a la lectoescritura en los niños y niñas de 4 a 5 años de la Unidad Educativa “Rumiñahui” tomando como referencia las actividades que se pueden realizar dentro de las Técnicas Lúdicas de Motricidad Fina. Esta guía “Habilidades y Destrezas” permitió mejorar el proceso enseñanza aprendizaje, de manera diferente, ya que se motivó a los niños y niñas de tal manera que aprendie...

  9. Preoperative assessment of thyroid nodules: role of ultrasonography and fine needle aspiration biopsy followed by cytology Avaliação preoperatória de nódulos thireóides: papel da ultrassonografia e da biópsia de aspiraçào por agulha fina, seguida de citologia

    Directory of Open Access Journals (Sweden)

    Rosalinda YA Camargo

    2007-01-01

    Full Text Available PURPOSE:To evaluate the preoperative assessment of thyroid nodules using ultrasound studies and cytology of nodular aspirates. SUBJECTS AND METHODS: 2,468 patients with thyroid nodules were examined from 1999 to 2005. All patients were clinically examined and underwent ultrasonography followed by fine-needle aspiration biopsy (FNAB and cytology. RESULTS:Nodules larger than 10 mm were classified ultrasonographically in a 4-tier system and received a score according to the criterion of possible malignancy. Cytological examinations were conducted independently by 2 cytologists and classified as benign (score 1, indeterminate (score 2, suspicious (score 3, and malignant (score 6. Combining both scores, an index was generated that would indicate a higher probability of malignancy (benign, doubtful, suspicious, and malignant. Thyroid surgery was performed in 274 patients. Of those, 115 patients had a score of 2 to 5 and only 8 had a histological diagnosis of thyroid cancer (6.9%. For patients with a score of 5 (n = 51, 11.5% had a malignant lesion, and 51% of the 61 patients with a score of 6 had confirmed thyroid cancer. Of the 98 patients with a combined score of 7 to 10, 99% had a histological confirmation of malignancy. CONCLUSIONS: The index score had a sensitivity of 94.1% and specificity of 77.5%. The overall accuracy was 85.8%. Therefore, we concluded that this methodology may improve the preoperative diagnosis of thyroid cancer in nodules larger than 10 mm. Association with other methods such as color Doppler echography, serum TSH concentration, galectin-3 expression analysis, and FDG/PET scan would be useful in avoiding the higher costs of thyroid surgical procedures.OBJETIVO: Avaliar a possibilidade de diagnóstico pré-operativo de nódulos da tireóide (de diâmetro superior a 10mm usando ultra-sonografia da glândula tireóide e citologia de punção aspirativa por agulha fina guiada pela ultra-sonografia. CASUÍSTICA E MÉTODOS: N

  10. Muestreo y análisis de desechos de talla. Un caso de estudio: Capa 2 Peñas de la Cruz 1.1 (Antofagasta de la Sierra, Catamarca Sampling techniques in lithic debitage analysis: A case study: layer 2 Peñas De La Cruz 1.1 site, Antofagasta de la Sierra, Catamarca

    Directory of Open Access Journals (Sweden)

    Jorge Alejandro Funes Coronel

    2012-07-01

    Full Text Available Este trabajo explora la incorporación de técnicas de muestreo en el análisis de desechos de talla. El objetivo general es la obtención de muestras que representen al conjunto de donde proceden, en este caso, los desechos de talla recuperados de la capa 2 (2° del sitio Peñas de la Cruz 1.1, localizado en Antofagasta de la Sierra, Catamarca. A fin de lograr lo propuesto se evalúan los alcances y limitaciones de tres tipos de muestreo aplicados en un mismo lote. Con el objeto de dar cuenta de las actividades de talla llevadas a cabo en el sitio, se presentan los resultados del análisis técnico-morfológico llevado a cabo sobre una muestra de desechos de talla (n= 300 extraída de un lote mayor (N= 2377.This paper explores the incorporation of sampling techniques in lithic débitage analysis. The overall objective is to obtain samples representative of the entire set from which they originated, in this case, débitage recovered from layer 2 from Peñas de la Cruz 1.1 site in Antofagasta de la Sierra, Catamarca. In order to accomplish this goal, the limitations of three types of sampling applied to the same lot were evaluated. With the goal of revealing the lithic production activities carried out at the site, the results of the technological analysis of a sample of materials (n= 300 collected from a larger lot (N= 2377 are presented.

  11. Aislamiento de antraquinonas y de pigmentos flavonoides en frutos de "yerba del pollo" (Alternanthera pungens H. B .K ., Amaranthaceae)

    OpenAIRE

    López de Ruiz, Rosa Evelia; Fusco, María del Rosario; Sosa, Ángela; Ruiz, Sohar Osvaldo

    1996-01-01

    A partir del extracto alcohólico de los frutos de "yerba del pollo" (Alternunthera pungens H.B.K.), planta de amplia difusión muy usada como digestiva en la medicina popular, se aislaron dos antraquinonas y cuatro pigmentos flavonoides como glicósidos identificados ambos grupos de compuestos mediante técnicas de espectroscopía de UV-Visible y por comparación en cromatografía de capa fina.

  12. 以ICF为指导的作业治疗对脑卒中患者ADL影响的临床研究%Effects of occupational therapy guided by ICF on ADL of stroke patients

    Institute of Scientific and Technical Information of China (English)

    韩东; 王金艳; 孙李慧子; 朱燕

    2016-01-01

    目的:探讨以ICF的核心要素为指导,制定有针对性的个体化作业康复目标、治疗计划,观察其对脑卒中患者ADL的影响.方法:选择60例脑卒中患者,对患者的活动与参与采用改良巴氏指数、健康调查表健康调查简表(SF-36)进行综合性评定,然后随机分成观察组和对照组,每组30例.2组均给予常规康复治疗,观察组加入运用中国版简明《国际功能残疾和健康分类》(ICF)核心要素量表进行评估,其结果做相关分析后制定个体化治疗方案.治疗前后采用健康调查简表(SF-36)、改良Barthel指数(MBI)、中国版简明核心ICF要素量表进行评价.结果:治疗8周后,2组患者SF-36、MBI评分均明显提高(P<0.05),ICF总分明显降低(P<0.05),观察组改善幅度均明显优于对照组(P<0.05).结论:以ICF理念和量表作为指导,以患者的诉求为中心,制定个性化的作业治疗方案,能更有成效更有针对性的达到康复目标,从而更有效的改善脑卒中患者的日常生活能力.

  13. Acúmulo de ácido oxálico e cristais de cálcio em ectomicorrizas de eucalipto.: II- formação de cristais de oxalato de cálcio induzida por fungos ectomicorrízicos em raízes laterais finas Accumulation of oxalic acid and calcium crystals in ectomycorrhizas of eucalypt.: II- calcium oxalate crystal formation induced by ectomicorrhizal fungi in fine lateral roots

    Directory of Open Access Journals (Sweden)

    Jhon Alexander Zambrano Gonzalez

    2009-06-01

    Full Text Available O eucalipto é eficiente na aquisição de Ca do solo, mas pouco se sabe sobre a participação das ectomicorrizas e dos ácidos orgânicos nesse processo em campo. O acúmulo de cristais de Ca (CaOx foi avaliado em, aproximadamente, 2.100 raízes laterais finas e ectomicorrizas do híbrido de Eucalyptus grandis x Eucalyptus urophylla, cultivado por 2,5 anos em área com topografia típica em meia laranja, com vertente côncavo-convexa, na região de Viçosa, MG. Técnicas de microscopia óptica e microscopia eletrônica de varredura foram usadas para a visualização dos CaOx. Em 73,7 % das raízes, ocorreu abundante acúmulo de drusas e grânulos de CaOx nas células do córtex. A presença conspícua de CaOx foi observada em 56,2 % das ectomicorrizas e em 17,5 % das raízes laterais finas não colonizadas, evidenciando o papel das micorrizas no acúmulo de Ca em eucalipto. A forma predominante dos CaOx foram as drusas nas ectomicorrizas e os grânulos cristalinos nas raízes. Os dez morfotipos de ectomicorrizas observados na área diferiram quanto à presença e à morfologia dos CaOx, o que pode representar distintas capacidades dos fungos ectomicorrízicos em fornecer Ca para a planta hospedeira. A análise da superfície do manto das ectomicorrizas por microscopia eletrônica de varredura não evidenciou a presença de CaOx nessa estrutura, confirmando que, nas condições avaliadas, o acúmulo de cristais limita-se ao córtex radicular. Este é o primeiro relato da ocorrência de CaOx em ectomicorrizas de eucalipto no Brasil, com dados que comprovam que há mecanismos de armazenamento de Ca nas ectomicorrizas em áreas com baixa disponibilidade do elemento.Eucalypt is efficient at taking up Ca from the soil, however little is known about the contribution of ectomycorrhizas and organic acids to this process under field conditions. The accumulation of calcium oxalate crystals (CaOx was evaluated in, approximately, 2,100 fine lateral roots

  14. Extreme resistance to two Brazilian strains of Potato virus Y (PVY in transgenic potato, cv. Achat, expressing the PVYº coat protein Resistência extrema a duas estirpes do Potato virus Y (PVY de batata transgênica, cv. Achat, expressando o gene da capa protéica do PVY O

    Directory of Open Access Journals (Sweden)

    Eduardo Romano

    2001-07-01

    Full Text Available The coat protein (CP gene of the potato virus Y strain "o" (PVY O was introduced into potato, cultivar Achat, via Agrobacterium tumefaciens-mediated transformation. Sixty three putative transgenic lines were challenged against the Brazilian strains PVY-OBR and PVY-NBR. An extremely resistant phenotype, against the two strains, was observed in one line, denominated 1P. No symptoms or positive ELISA results were observed in 16 challenged plants from this line. Another clone, named as 63P, showed a lower level of resistance. Southern blot analysis showed five copies of the CP gene in the extremely resistant line and at least three copies in the other resistant line. The stability of the integrated transgenes in the extreme resistant line was examined during several in vitro multiplications over a period of three years, with no modification in the Southern pattern was observed. The stability of the transgenes, the absence of primary infections and the relatively broad spectrum of resistance suggest that the extremely resistant line obtained in this work can be useful for agricultural purposes.O gene da capa protéica (CP do Potato virus Y estirpe "o", foi introduzido em batata cultivar Achat, via Agrobacterium tumefaciens. Sessenta e três linhas possivelmente transgênicas foram desafiadas com as estirpes brasileiras PVY-OBR e PVY-NBR. Uma linha apresentou extrema resistência às duas estirpes inoculadas, e foi denominado clone 1P. Não foram observados sintomas sistêmicos de infecção e as plantas foram negativas em Elisa. Outra linha, denominada clone 63P, mostrou algum nível de resistência. Análises por Southern blot indicaram a presença de pelo menos cinco cópias do gen CP no clone 1P e pelo menos três cópias no clone 63P. A estabilidade do gene introduzido no clone 1P foi avaliada durante três anos, após várias multiplicações in vitro. Não foram observadas mudanças no padrão do Southern blot. A estabilidade do transgene, na

  15. Elementos extra-musicais na obra de K-ximbinho: questões sobre iconografia musical em suas capas de disco entre 1950 e 1960 Extra-musical elements in the work of K-Ximbinho: questions about musical iconography in their record covers between 1950s and 1960s

    Directory of Open Access Journals (Sweden)

    Pablo Garcia da Costa

    2011-06-01

    Full Text Available K-ximbinho participou juntamente com outros músicos entre as décadas de 1950 e 1960 de um processo que visava modernizar o samba e o choro pela introdução dos elementos diversos do jazz. Esse processo de mistura entre gêneros musicais distintos, compreendido entre os músicos da época como "samba-jazz" ou "choro jazzístico", não se limitava em misturar elementos rítmicos harmônicos e melódicos, mas também negociar a presença de termos, imagens e vestimentas da cultura estadunidense no Rio de Janeiro pré Bossa Nova. É possível verificar nas capas de discos gravados por K-ximbinho que essa negociação entre duas culturas se manifestava em forma de imagens e textos e visavam informar ao consumidor a que cada obra se destinava, ressaltando a inovação do samba e choro e propondo a criação desse novo estilo musical.K-Ximbinho participated along with other musicians from the 1950s and 1960s in a process aimed at modernizing the samba and choro in the introduction of various jazz.elements into Brazilian traditional styles. This blending of different musical genres, known at the time as "samba-jazz" or "choro jazz" was not limited to mixing rhythmic, harmonic and melodic elements, but also in the negotiation of present expressions, images and ways from North-American culture in Rio de Janeiro in a pre Bossa Nova era. It's possible to verify on the covers of albums recorded by K-Ximbinho that the negotiation between these two cultures is manifested in the form of images and texts meant to inform the consumer how each work was intended, highlighting the innovation of samba and choro and proposing the creation of this new musical style.

  16. Detección de solapes en capas vectoriales : GISProp

    OpenAIRE

    Serradilla Díez, Marcos

    2015-01-01

    Este proyecto de fin de carrera surge como una necesidad de realizar un control de calidad en un Sistema de Información Geográfico (SIG en adelante). En el caso de GISProp, su objetivo es el de localizar en un conjunto de objetos cartográficos si existe superficie duplicada con algún otro objeto cartográfico del mismo tipo. Para ello, se utilizan técnicas de agrupamiento espacial, sistemas expertos y una aplicación GIS para obtener el área de los objetos cartográficos. Además, los ...

  17. Capa, Expediente e Editorial da Edição

    OpenAIRE

    Montiel, José Maria; IPADE

    2013-01-01

    editorial editorial editorial editorialeditorial editorial editorialeditorial editorial editorial editorialeditorial editorial editorialeditorial editorial editorial editorialeditorialeditorial editorial editorial editorialeditoriaeeditorial editorial editorial editorialeditorial editorial editorialditorial editorial editorial editorialeditorieditorial editorial editorial editorialeditorieditorial editorial editorial editorialeditorial editorial editorialal edieditorial editorial editorial ed...

  18. 基于ICF核心分类组合肥胖症功能特点分析与运动康复策略研究%Functioning and Exercise Rehabilitation Strategies of Obesity Based on ICF-Core Set of Obesity

    Institute of Scientific and Technical Information of China (English)

    曹仪钦; 王国祥

    2015-01-01

    This paper analyzed the functioning and characteristic of body function, body structure, activities and participation and envi-ronments based on the theories and methods of International Classification of Functioning, Disability and Health (ICF). It was concluded that environment was the main reason of the development of obesity, body structure was an objective indicator of determine of obesity and also the degree of obesity's intervention, physical function changes reflected the hazards and their severity, and activity and participation was an out performance of obesity's difficulties or obstacles. Based on these conclusions, several corresponding sports rehabilitation strategies were proposed.%基于《国际功能、残疾和健康分类》(ICF)理论与方法,对肥胖症在身体功能、身体结构、活动与参与、环境因素4个方面的功能特点进行分析。结果认为,身体功能反映肥胖症的危害及其病变程度,身体结构是判定肥胖程度及其干预效果的客观指标,活动与参与是肥胖者活动困难或障碍的外在表现,环境因素是肥胖症发生发展的主要原因,并在此基础上提出了相应的运动康复策略。

  19. Feasibility of brief ICF core sets for Chinese stroke patients in community-based rehabilitation%中国版简明ICF核心要素量表在社区脑卒中康复中应用的可行性研究

    Institute of Scientific and Technical Information of China (English)

    徐国会; 俞卓伟; 徐悦莹; 郑洁皎

    2011-01-01

    Objective To explore the application and feasibility of brief ICF core sets for Chinese stroke patients in community-based rehabilitation. Method One hundred and forty-six community stroke patients were measured with brief ICF Core Sets for Chinese stroke patients, the NIH Stroke Scale (NIHSS) , Barthel Index (BI) and SF-36. Repetition reliability, internal consistency and face validity were analyzed with Kappa test, Conbach α index and Pearson correlation analysis respectively in the process of PNF technique for six months. Result The brief ICF Core Sets for Chinese stroke patients had very good repetition reliability among components of body function, body structure, activity and participation with Kappa=0.782-0.935 and environment factor with Kappa=0.578-0.931before PNF intervention and with Kappa = 0 .787-0.965 and Kappa = 0.608-0.969 after intervention respectively. Good internal consistency existed in body function , activity and participation and environment factor with α= 0.774-0.926 before PNF intervention and with α= 0.786-0.953 after PNF rehabilitation. There was concurrent validity for the ICF components with BI , NIHSS and SF-36. Correlation coefficient between ICF stroke scales and NIHSS, BI and SF-36 were 0 . 848,0 . 867,0.798 before rehabilitation intervention and 0.854,0 . 879,0 . 832 after PNF intervention respectively . Conclusion Brief ICF core sets evaluation was clinically feasible for stroke community-based rehabilitation with good reliability and validity, and could be further applied and promoted.%目的 探讨中国版脑卒中简明ICF核心要素鼍表(以下简称中国版ICF简表)在社区脑卒中康复中应用的可行性.方法 146例社区脑卒中患者,接受以本体感觉神经肌肉促进疗法(PNF)为主的康复治疗6个月.按照中国版ICF简表、美国国立卫生研究院卒中量表(NIHSS)、Barthel指数(BI)和SF-36的规则进行治疗前后评定.效度研究采用校标效度,以Spearman相关性判

  20. Comparison of Barriers of Activity and Participation for 3-6 Years Aged Children with Cerebral Palsy, Intellectu-al Disability, and Autism Using ICF-CY Questionnaire%3~6岁脑性瘫痪、智力残疾、孤独症儿童活动和参与功能障碍比较

    Institute of Scientific and Technical Information of China (English)

    梁兵; 马洪卓; 邱卓英; 李沁燚; 王金元

    2015-01-01

    Objective To compare the features of activity and participation difficulty of children with cerebral palsy, intellectual disabili-ty and autism. Methods 42 children with cerebral palsy, intellectual disability, and autism aged 3-6 years were evaluated with ICF-CY Ques-tionnaire. Results There were mild barriers in the domains of learning and applying knowledge, communication, mobility, self-care, domes-tic life and major life areas, and the moderate barriers in the domains of general tasks and demands, interpersonal interactions and relations. There were more barriers in learning and applying knowledge in children with cerebral palsy and intellectual disability than those with au-tism. Conclusion There are various features in activity and participation difficulty in children with cerebral palsy, intellectual disability or autism, which required diversity of educational rehabilitation strategies.%目的:比较脑瘫、智力残疾、孤独症儿童主要活动和参与障碍的特点。方法3~6岁参与教育与康复训练的残疾儿童42名,采用ICF-CY功能检查表进行调查。结果残疾儿童在学习和应用知识、交流、活动、家庭生活、自理和主要生活领域属于轻度障碍;在一般任务和要求、人际交往与人际关系领域属于中度障碍。智力残疾和脑瘫儿童在学习和应用知识领域的障碍高于孤独症儿童。结论脑瘫、智力残疾、孤独症儿童的活动和参与功能障碍有其不同特点,应构建多样性、阶段性、连续性的教育康复策略,实现残疾儿童康复与教育效果的最大化。

  1. The world developing tendency of magnetism and magnetic materials searched from the International Conference on Ferrite(ICF)%从国际铁氧体会议(ICF)看磁学与磁性材料的发展趋势

    Institute of Scientific and Technical Information of China (English)

    何水校

    2001-01-01

    @@1 前言--ICF的简要历史   国际铁氧体会议(International Conference on  Ferrite,ICF)是由日本东京工业大学教授武井武先生等人于六 十年代中期倡导并发起的。在国际磁学界的广泛支持下,并且获得了日本粉体 和粉末冶金协会、TDK、三菱和松下等大公司的鼎力相助。第一届国际铁氧 体会议(ICF1)于1970年7月在日本京都顺利举行,会议颇获成功。 三十年来,ICF已先后举行过8次,平均每四年召开一次,ICF已成为I UPAP(the International Union of Pur e and Applied Physics)正式承认的、目前磁学界颇 具影响的一个国际会议。表1列出了历届ICF会议的一些情况。

  2. MOAGEM FINA DE MINÉRIO DE COBRE DE ALTA EFICIÊNCIA ENERGÉTICA

    Directory of Open Access Journals (Sweden)

    Mauricio Guimarães Bergerman

    2014-07-01

    Full Text Available Na área de moagem secundária, ou remoagem, a preocupação com a eficiência energética se mostra de extrema importância. Em geral, os consumos específicos desta etapa são superiores aos da etapa primária. Além disso, tem se observado uma tendência de afinamento das granulometrias de moagem nos novos projetos de minerais metálicos, o que leva a cada vez uma maior necessidade de gastos nesta etapa, tanto em termos de custos de implantação como de operação. Nos novos projetos de cobre da Vale, granulometrias de remoagem da ordem de 40 a 20 m tem se mostrado necessárias. Os moinhos de bolas convencionais, adequados para moagem primária, mostram-se poucos eficientes em termos de aproveitamento de energia, quando são necessários produtos abaixo de 50 m. A fim de avaliar as melhores alternativas tecnológicas disponíveis para estas aplicações de remoagem, a Vale está tem desenvolvido estudos em moinhos de carga agitada, como Vertimill®. O presente trabalho irá apresentar os resultados de amostragens em escala industrial com o moinho Vertical da Usina do Sossego nos primeiros anos de operação do mesmo, comparando os resultados com os consumos específicos determinados em escala laboratorial.

  3. Carboidratos como fonte de compostos para a indústria de química fina

    Directory of Open Access Journals (Sweden)

    Vitor Francisco Ferreira

    2013-01-01

    Full Text Available Coal, oil, natural gas, and shale gas are biomass that is formed millions of years ago. These are non-renewable and depleting, even considering the recent discovery of new sources of oil in the presalt and new technologies for the exploitation of shale deposits. Currently, these raw materials are used as a source of energy production and are also important for the production of fine chemicals. Since these materials are finite and their (oil price is increasing, it is clear that there will be a progressive increase in the chemical industry to use renewable raw materials as a source of energy, an inevitable necessity for humanity. The major challenge for the society in the twenty first century is to unite governments, universities, research centers, and corporations to jointly act in all areas of science with one goal of finding a solution to global problems, such as conversion of biomass into compounds for the fine chemical industry.Non-renewable raw materials are used in the preparation of fuels, chemical intermediates, and derivatives for the fine chemical industry. However, their stock in nature has a finite duration, and their price is high and will likely increase with their depletion. In this scenario, the alternative is to use renewable biomass as a replacement for petrochemicals in the production of fine chemicals. As the production of biomass-based carbohydrates is the most abundant in nature, it is judicious to develop technologies for the generation of chain products (fuels, chemical intermediates, and derivatives for the fine chemicals industry using this raw material. This paper presents some aspects and opportunities in the area of carbohydrate chemistry toward the generation of compounds for the fine chemical industry.

  4. Veřejné finance a finační trhy

    OpenAIRE

    Kahoun, Jakub

    2010-01-01

    Bachelor thesis deals with public finance and financial markets. Author analyzes the basic terms of the solved problems in the theoretical part: public finance, public budgets, public revenues, public expenditures, public debt, financial markets and their relations. The analytical part is trying to find an answer to the question, what tools the state have to finance the national debt and how to finance it from the government bond yield.

  5. Comparação dos instrumentos de avaliação do sono, cognição e função no acidente vascular encefálico com a classificação internacional de funcionalidade, incapacidade e saúde (CIF Comparison of instruments for sleep, cognition and function evaluation in stroke patients according to the international classification of functioning, disability and health (ICF

    Directory of Open Access Journals (Sweden)

    Tania F. Campos

    2012-02-01

    Full Text Available CONTEXTUALIZAÇÃO: A Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF precisa ser empregada amplamente na pesquisa e prática clínica, mas há escassez de trabalhos que vinculem sua utilização a instrumentos de avaliação utilizados na fisioterapia. OBJETIVO: Comparar os instrumentos de avaliação do sono, cognição e função com a CIF em pacientes com AVE. MÉTODOS: Participaram 12 pacientes (seis mulheres, com idade média de 55,4 (±6,2 anos e tempo de recuperação de sete a 36 meses. Os pacientes foram avaliados pelo Índice de Qualidade do Sono de Pittsburgh (IQSP, Miniexame do Estado Mental (MEEM e Índice de Barthel (IB. A comparação da frequência das categorias registradas da CIF com os itens dos instrumentos foi realizada por meio do teste de Fisher e teste do qui-quadrado. A concordância das categorias registradas por dois avaliadores foi analisada pelo Índice de Kappa. RESULTADOS: Na análise do IQSP, encontrou-se um escore médio de 5,0 (±3,0; para o MEEM, de 22,5 (±3,4 e para o IB, de 74,6 (±17,2. Na CIF, as alterações identificadas nos instrumentos anteriores foram registradas em 46 categorias, sendo a maior parte no componente "Funções do Corpo", seguido de "Atividades e Participação". Encontrou-se uma concordância interavaliador de 0,87 para o IQSP (substancial, de 0,44 para o MEEM (moderada e de 0,39 para o IB (justa. CONCLUSÕES: Os resultados indicam que as concordâncias de cada instrumento foram muito diferentes, sugerindo a necessidade de maior utilização desses instrumentos na prática fisioterapêutica, a fim de otimizar a formulação e padronização do diagnóstico fisioterapêutico.BACKGROUND: The International Classification of Functioning, Disability and Health (ICF should be widely used in research and clinical practice, but there are few studies that do so with the evaluation instruments used in physical therapy. OBJECTIVE: To compare instruments that evaluate

  6. The effects of occupational therapy guided by ICF theory on the ADL in elderly hemiplegic stroke patients%ICF理念下的作业训练对老年脑卒中偏瘫患者日常生活能力及生存质量的影响

    Institute of Scientific and Technical Information of China (English)

    陈宇岚; 陆兴华; 史庭璋; 陈文华

    2016-01-01

    目的 探讨ICF(International Classification of Functioning,Disability and Health,国际功能、残疾和健康分类)理念下的作业治疗对脑卒中偏瘫患者日常生活活动能力(ability of daily living,ADL)及生存质量的影响.方法 将60例老年脑卒中偏瘫患者随机分为观察组与对照组各30例,观察组采用ICF理念下的作业治疗进行干预,对照组采用传统作业治疗,两组患者均接受常规康复治疗.人选时和治疗6个月后分别采用Barthel指数(Barthel Index,BI)、功能综合评定量表(Functional Comprehensive Assessment,FCA)及SF-36生活质量调查表进行评定.结果 治疗6个月后,同组比较BI、FCA评分均较治疗前有提高(P<0.05),治疗后观察组BI、FCA及SF-36评分均高于对照组(P<0.05).结论 相较于传统作业治疗,ICF理念下的作业治疗有助于进一步改善脑卒中偏瘫患者的ADL能力,提高生活生存质量.

  7. Evaluación estacional de fitoestrógenos en heces de machos del murciélago frutero jamaiquino (Artibeus jamaicensis Leich, 1821).

    OpenAIRE

    Arturo Salame-Méndez; Alondra Castro-Campillo; Karina Olvera-Olvera; Héctor Serrano; Fernando Huerta-García; Juan José Esquivel-Florencio; Jorge Haro-Castellanos; Miguel Ángel Briones-Salas; José Ramírez-Pulido; José Luís Gómez-Olivares; María Dolores García-Suárez

    2012-01-01

    Artibeus jamaicensis Leich, 1821, obtiene los requerimientos energéticos básicos para subsistir y reproducirse a partir de frutos y hojas, aún cuando algunos de ellos podrían contener fitoquímicos nocivos que al actuar como estrógenos (fitoestrógenos, FTE); provocan disrupción endócrina en su fisiología reproductiva. Los FTE derivan de isoflavonas, lignanos y coumestanos, compuestos fenólicos fluorescentes que pueden ser detectados en sus heces, mediante cromatografía en capa fina. Aq...

  8. Rehabilitation and control of cerebral injury and palsy disability by application of multiple integration methods of preventive treatment of disease and ICF theoretical design%应用治未病与ICF理论设计多元融合式康复控制脑损伤脑瘫残疾

    Institute of Scientific and Technical Information of China (English)

    陈世英

    2013-01-01

    Objective It is to observe the effect of rehabilitation and control of cerebral injury and palsy disability by application of effective and multiple integration methods of preventive treatment of disease and ICF theoretical design. Methods 131 infants who meet the diagnosis of cerebral injury and palsy were randomly paired and divided into two groups, the multiple integration rehabilitation was used in observation group, the intensive physical type rehabilitation was used in control group. By assessment of Gese11 Developmental Scale, emotion and behaviors nervimotion and Infant-Junior High School Student' s Social Living Ability Scale and the disability assessment criteria, the comprehensive efficacies of two groups were compared. Results The average adaptive developmental quotients of the observation group were higher, their emotional behavior symptoms were reduced, the mental deficiency was lower and admission rate of the kindergarten was higher. Conclusion The multiple integration type rehabilitation by design and application can improve the overall rehabilitation effect and reduce the cerebral injury and palsy disability.%目的 观察应用治未病与ICF理论设计的高效、多元融合式康复方法控制脑损伤脑瘫的效果.方法 将符合脑损伤脑瘫诊断的131例婴儿随机配对分为2组:观察组采用多元融合式方法康复,对照组采用运动强化式方法康复.以Gesell发育量表、情绪和行为神经运动测评、婴儿-初中生社会生活适应量表和残疾评定标准评定2组综合疗效.结果 观察组平均适应性发育商较高,情绪行为症状减少,智残率低,入园率高.结论 多元融合式康复能提高整体康复效果,减少脑损伤脑瘫残疾.

  9. Target debris collection studies for inertial confinement fusion (ICF) experiments

    Science.gov (United States)

    Grim, G. P.; Archuleta, T. N.; Bradley, P. A.; Fowler, M. M.; Hayes, A. C.; Jungman, G.; Obst, A. W.; Rundberg, R. S.; Vieira, D. J.; Wang, Y. Q.; Wilhelmy, J. B.

    2010-08-01

    At the recently completed National Ignition Facility (NIF) at Lawrence Livermore National Laboratory, the initial set of diagnostics to be deployed are focused on measuring neutrons and γ's generated by d(t,n)α reactions in the imploded capsule. Although valuable for understanding pre-ignition experiments, this abbreviated diagnostic suite provides an incomplete picture of the plasma conditions obtained. Prompt radiochemical techniques, based on induced neutron and charged particle reactions within the imploded target, provide a novel and interesting new perspective. To enable these techniques requires the collection and assay of activated target material. In Nov. 2008, experiments were performed using the Omega Laser at the University of Rochester to study the efficiency of collecting debris from directly driven targets. Results from these experiments indicate that target debris was successfully collected, and the debris thermalization and transport scheme enhanced the debris collection up to 347% over direct collection.

  10. Target debris collection studies for inertial confinement fusion (ICF) experiments

    Energy Technology Data Exchange (ETDEWEB)

    Grim, G P; Archuleta, T N; Bradley, P A; Fowler, M M; Hayes, A C; Jungman, G; Obst, A W; Rundberg, R S; Vieira, D J; Wang, Y Q; Wilhelmy, J B, E-mail: gpgrim@lanl.go [Los Alamos National Laboratory, PO Box 1663, Los Alamos, NM 87545 (United States)

    2010-08-01

    At the recently completed National Ignition Facility (NIF) at Lawrence Livermore National Laboratory, the initial set of diagnostics to be deployed are focused on measuring neutrons and {gamma}'s generated by d(t,n){alpha} reactions in the imploded capsule. Although valuable for understanding pre-ignition experiments, this abbreviated diagnostic suite provides an incomplete picture of the plasma conditions obtained. Prompt radiochemical techniques, based on induced neutron and charged particle reactions within the imploded target, provide a novel and interesting new perspective. To enable these techniques requires the collection and assay of activated target material. In Nov. 2008, experiments were performed using the Omega Laser at the University of Rochester to study the efficiency of collecting debris from directly driven targets. Results from these experiments indicate that target debris was successfully collected, and the debris thermalization and transport scheme enhanced the debris collection up to 347% over direct collection.

  11. The ICF status and plans in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Moses, E.I.; Miller, G.H.; Kauffman, R.L. [Lawrence Livermore National Laboratory, Livermore, CA (United States)

    2006-06-15

    The United States continues to maintain its leadership in inertial confinement fusion as it moves toward the goal of ignition. The flagship of the program is the National Ignition Facility (NIF) presently under construction at Lawrence Livermore National Laboratory. Experiments had begun on the first four beams of the National Ignition Facility just at the time of the last IFSA Conference. Several new successful campaigns have been conducted since then in planar hydrodynamics and hohlraums as well as activating the VISAR diagnostic for equation of state experiments. Highlights of these results will be reviewed. Presently, the four beam experimental capability has been suspended while the first eight beams are being installed as the first step in building out the project. Meanwhile, much progress has been made in developing ignition designs for using NIF. An array of designs having several ablator materials have been shown computationally to ignite with energies ranging from the design energy to as low as 1 MJ of laser energy. Alternative direct drive designs in the NIF indirect drive configuration have been developed by LLE. This wide array of design choices has increased the chance of achieving ignition sooner on the facility. Plans are now being developed to begin an ignition experimental campaign on NIF in 2010, a little over a year after completion of the facility. Other US facilities are also implementing improved capabilities. Peta-watt lasers are now under construction at the University of Rochester and Sandia National Laboratory. The Z pulsed power machine at Sandia National Laboratory is being refurbished to improve its performance. The ongoing research program at the OMEGA laser at the University of Rochester and the Z machine at Sandia National Laboratory as well as at the Nike, Trident and Janus lasers remain strong, performing experiments supporting the NIF ignition plan and direct drive ignition. There also is an active program in the broader field of high energy density science on these facilities. These activities will be reviewed here as well as presented in talks throughout the conference. (authors)

  12. Mach-Zehnder Fiber-Optic Links for ICF Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Miller, E. K., Hermann, H. W.

    2012-11-01

    This article describes the operation and evolution of Mach-Zehnder links for single-point detectors in inertial confinement fusion experimental facilities, based on the Gamma Reaction History (GRH) diagnostic at the National Ignition Facility.

  13. ICF Gamma-Ray Yield Measurements on the NIF

    Science.gov (United States)

    Herrmann, H. W.; Kim, Y. H.; Hoffman, N. M.; Stoeffl, W. S.; Watts, P. W.; Carpenter, A. C.; Church, J. A.; Liebman, J.; Grafil, E.

    2011-10-01

    The primary objective of the NIF Gamma Reaction History (GRH) diagnostic is to provide bang time and burn width information in order to constrain implosion simulation parameters such as shell velocity and confinement time. This is accomplished by measuring DT fusion γ-rays with energy-thresholded Gas Cherenkov detectors that convert MeV γ-rays into UV/visible photons for high-bandwidth optical detection. For yield determination, absolute uncertainties associated with the d(t,n) α/d(t,γ)5He branching ratio and detector response are removed by cross-calibrating the GRH signal against independent neutron yield measurements of directly-driven DT exploding pushers with negligible neutron downscatter. The GRH signal can then be used to make Total DTn Yield inferences on indirectly-driven, cryogenically-layered DT implosions which achieve high areal density and hence scatter a significant fraction of DTn out of the 14 MeV primary peak. By comparing the Total DTn Yield from γ-ray measurements with the Primary DTn Yield (13-15 MeV) from neutron measurements, the Total Downscatter Fraction (TDSF) can be inferred. Results of recent measurements will be presented. This work supported by US DOE under contract DE-AC52-06NA25396.

  14. ICF Gamma-Ray measurements on the NIF

    Science.gov (United States)

    Herrmann, Hans; Kim, Y.; Hoffman, N. M.; Batha, S. H.; Stoeffl, W.; Church, J. A.; Sayre, D. B.; Liebman, J. A.; Cerjan, C. J.; Carpenter, A. C.; Grafil, E. M.; Khater, H. Y.; Horsfield, C. J.; Rubery, M.

    2013-10-01

    The primary objective of the NIF Gamma Reaction History (GRH) diagnostic is to provide bang time and burn width information in order to constrain implosion simulation parameters such as shell velocity and confinement time. This is accomplished by measuring DT fusion gamma-rays with energy-thresholded Gas Cherenkov detectors that convert MeV gamma-rays into UV/visible photons for high-bandwidth optical detection. Burn-weighted CH ablator areal density is also inferred based on measurement of the 12C(n,n') gammas emitted at 4.44 MeV from DT neutrons inelastically scattering off carbon nuclei as they pass through the plastic ablator. This requires that the four independent GRH gas cells be set to differing Cherenkov thresholds (e.g., 2.9, 4.5, 8 & 10 MeV) in order to be able to unfold the primary spectral components predicted to be in the gamma ray energy spectrum (i.e., DT γ 27Al & 28Si (n,n') γ from the thermo-mechanical package (TMP); and 12C(n,n' γ from the ablator). The GRH response to 12C(n,n') γ is calibrated in-situ by placing a known areal density of carbon in the form of a puck placed ~6 cm from a DT exploding pusher implosion. Comparisons between inferred gamma fluences and simulations based on the nuclear cross sections databases will be presented. Supported by US DOE NNSA.

  15. Ray-based calculations of laser backscatter in ICF targets

    CERN Document Server

    Strozzi, D J; Hinkel, D E; Froula, D H; London, R A; Callahan, D A

    2008-01-01

    A steady-state model for Brillouin and Raman backscatter along a laser ray path is presented. The daughter plasma waves are treated in the strong damping limit, and have amplitudes given by the (linear) kinetic response to the ponderomotive drive. Pump depletion, inverse-bremsstrahlung damping, bremsstrahlung emission, Thomson scattering off density fluctuations, and whole-beam focusing are included. The numerical code Deplete, which implements this model, is described. The model is compared with traditional linear gain calculations, as well as ``plane-wave'' simulations with the paraxial propagation code pF3D. Comparisons with Brillouin-scattering experiments at the Omega Laser Facility show that laser speckles greatly enhance the reflectivity over the Deplete results. An approximate upper bound on this enhancement is given by doubling the Deplete coupling coefficient. Analysis with Deplete of an ignition design for the National Ignition Facility (NIF), with a peak radiation temperature of 285 eV, shows enco...

  16. Site support program plan for ICF Kaiser Hanford Company

    Energy Technology Data Exchange (ETDEWEB)

    Dieterle, S.E.

    1996-09-27

    The Fiscal Year (FY) 1997 Inftastructure Program Site Support Program Plan (SSPP) addresses the mission objectives, workscope, work breakdown structures (WBS), management approach, and resource requirements for the Infrastructure Program. Attached to the plan are appendices that provide more detailed information associated with scope definition.

  17. Preparation and properties of polymer foams for ICF targets

    Energy Technology Data Exchange (ETDEWEB)

    Letts, S.A.; Lucht, L.M.

    1986-09-01

    Low density small cell sized foams were developed to localize the liquid DT layer in a direct drive wetted foam laser fusion target. We have developed foams made from ultrahigh molecular weight polyethylene gels and polystyrene inverse emulsions. Materials in the density range of from 0.020 to 0.300 g/cc were prepared and characterized for cell size, mechanical properties, machinability, specific surface area, and wetting. Foams with a density of 0.05 g/cc were made with a cell size of less than 5 ..mu..m. A cell structure model was developed which relates the density and specific surface area to cell size and cell wall thickness. Wetting tests in organic solvents and in liquid hydrogen were used to characterize the capillary pressure, pore structure and uniformity of the foams. 13 refs., 9 figs., 2 tabs.

  18. Simulations of the impact of localized defects on ICF implosions

    Science.gov (United States)

    Milovich, Jose; Robey, Harry; Weber, Christopher; Sepke, Scott; Clark, Daniel; Koning, Joe; Smalyuk, Vladimir; Martinez, David

    2016-10-01

    Recent experiments have identified the tent membranes that support the capsule as a source of a large azimuthal perturbation at the point of departure from the surface. Highly-resolved 2D simulations have shown that vorticity generated by the interaction of the ablated capsule material and the tent allows for the penetration of cold ablator material into the burning hot-spot likely cooling the central burning plasma. These observations have motivated the search for alternative supporting methods. One of the techniques being considered uses the existing fill-tube (needed to deliver the cryogenic fuel) supported against gravity by a thin rod (cantilever) spanning the hohlraum diameter. Recent experiments have assessed the perturbation induced on the target as the rod is positioned along the fill-tube at different distances from the capsule surface and found optical-depth modulations oriented along the cantilever direction, possibly caused by laser spot shadowing or hydro-coupling. To fully understand the data we have undertaken an extensive study of highly-resolved 2D integrated simulations abled to resolve the 12 um diameter cantilever. Results of our computations and comparison with the experiments will be presented. Prepared by LLNL under Contract DE-AC52-07NA27344.

  19. Results from neutron imaging of ICF experiments at NIF

    Science.gov (United States)

    Merrill, F. E.; Danly, C. R.; Fittinghoff, D. N.; Grim, G. P.; Guler, N.; Volegov, P. L.; Wilde, C. H.

    2016-03-01

    In 2011 a neutron imaging diagnostic was commissioned at the National Ignition Facility (NIF). This new system has been used to collect neutron images to measure the size and shape of the burning DT plasma and the surrounding fuel assembly. The imaging technique uses a pinhole neutron aperture placed between the neutron source and a neutron detector. The detection system measures the two-dimensional distribution of neutrons passing through the pinhole. This diagnostic collects two images at two times. The long flight path for this diagnostic, 28 m, results in a chromatic separation of the neutrons, allowing the independently timed images to measure the source distribution for two neutron energies. Typically one image measures the distribution of the 14 MeV neutrons, and the other image measures the distribution of the 6-12 MeV neutrons. The combination of these two images has provided data on the size and shape of the burning plasma within the compressed capsule, as well as a measure of the quantity and spatial distribution of the cold fuel surrounding this core. Images have been collected for the majority of the experiments performed as part of the ignition campaign. Results from this data have been used to estimate a burn-averaged fuel assembly as well as providing performance metrics to gauge progress towards ignition. This data set and our interpretation are presented.

  20. Actividad catalítica de zeolitas de porosidad jerarquizada en diferentes reacciones de Química Fina

    OpenAIRE

    García Cadenas, Carlos

    2011-01-01

    Proyecto Fin de Carrera leído en la Universidad Rey Juan Carlos en el curso académico 2010/2011. Directores del Proyecto: Rafael García Muñoz y María Linares Serrano Este proyecto forma parte de una línea de investigación, actualmente desarrollada por el Grupo de Tecnología Química y Ambiental de la Universidad Rey Juan Carlos, sobre el diseño de nuevos catalizadores heterogéneos en procesos químicos de interés industrial. En este caso, la investigación está centrada en la síntesi...

  1. Element determination of fine particles in environmental aerosols using PIXE; Determinacion elemental de paticulas finas en aerosoles ambientales usando PIXE

    Energy Technology Data Exchange (ETDEWEB)

    Garcia O, B. [ITT, 50000 Toluca (Mexico); Aldape U, F. [ININ, 52750 La Marquesa, Estado de Mexico (Mexico)]. e-mail: gaolivab@gmail.com

    2007-07-01

    The Mexico city is classified as one of the more populated cities of the world which presents a decrease in the air quality and that gives place to a severe problematic in atmospheric pollution. To cooperate in the solution of this problem it is necessary to carry out studies that allow a better knowledge of the atmosphere of the city. This study presents the results of a monitoring campaign of fine particle carried out from September 21 to December 12, 2001 in three sites of the Mexico City center area. The samples were collected every third day with a collector type unit of heaped filters (Gent). The analysis of these samples was carried out in the 2 MV accelerator of the National Institute of Nuclear Research (ININ) applying the PIXE technique and with this analysis its were identified in the samples approximately 15 elements in each one of the 3 sites and was calculated the concentration in that its were present. With these results a database was created and by means of it mathematical treatment the Enrichment factor (FE), the time series of each element and the multiple correlation matrix were evaluated. The obtained results showed that the Civil Registration site (Salto del Agua) it was the more polluted coinciding that to a bigger concentration of activities a bigger increase in the pollution is generated. (Author)

  2. AUMENTO EN LA RESISTENCIA A LA CORROSIÓN DE UN ACERO T91 ALUMINIZADO

    Directory of Open Access Journals (Sweden)

    LUZ S. QUINTERO

    2011-01-01

    Full Text Available El acero ferrítico T91 ha sido ampliamente utilizado en plantas de generación de energía eléctrica, calderas y plantas nucleares. Sin embargo, su resistencia a la oxidación se ve gravemente afectada a temperaturas superiores a los 600ºC. En esta investigación se empleó la técnica de cementación empacada para aluminizar un acero T91 y se encontraron las condiciones óptimas para la formación de un recubrimiento libre de porosidad y con espesor uniforme (300 micras. Se evaluó la capa de óxido formada luego de una exposición a 800ºC en atmósfera de aire. La caracterización del recubrimiento y de la capa de óxido (Al2O3 se llevó a cabo empleando un microscopio electrónico de barrido (SEM, Espectroscopia de Rayos X (EDX y mapping. Se comprobó una buena resistencia a la oxidación del acero T91 aluminizado, debido a la formación de una fina capa continua de óxido de aluminio de aproximadamente 6 micras de espesor luego de una exposición de 7 días.

  3. Molecular cloning and functional expression of a Drosophila receptor for the neuropeptides capa-1 and -2

    DEFF Research Database (Denmark)

    Iversen, Annette; Cazzamali, Giuseppe; Williamson, Michael

    2002-01-01

    The Drosophila Genome Project website contains an annotated gene (CG14575) for a G protein-coupled receptor. We cloned this receptor and found that the cloned cDNA did not correspond to the annotated gene; it partly contained different exons and additional exons located at the 5(')-end of the ann...

  4. Comportamiento de las capas superficiales deformadas plásticamente por el desgaste en elementos circulares

    Directory of Open Access Journals (Sweden)

    Dayanis Alcántara Borges

    2008-01-01

    Full Text Available Se analizó que el desgaste por deslizamiento tiene una gran influencia en los sistemas pasador/casquillo, por el deslizamiento del casquillo sobre el pasador sobre la parte externa del mismo en una pista curva y en él se estudia el comportamiento microestructural del acero AISI 1045 empleado en los equipos de laboreo minero de la industria cubana del níquel. Para las pruebas se utilizaron probetas de pasadores antes de su puesta en funcionamiento y pasadores retirados después de su vida útil. Se empleó el método de microcospía óptica para analizar el efecto del endurecimiento por deformación.

  5. CAPA-gene products in the haematophagous sandfly Phlebotomus papatasi (Scopoli) - Vector for leishmaniasis disease

    Science.gov (United States)

    Sandflies (Phlebotominae, Nematocera, Diptera) are responsible for transmission of leishmaniasis and other protozoan-borne diseases in humans, and these insects depend on the regulation of water balance to cope with the sudden and enormous intake of blood over a very short time period. The sandfly ...

  6. Modelo Simulink de la capa física de Bluetooth

    OpenAIRE

    Sierra González, María

    2009-01-01

    El objetivo de este proyecto de fin de carrera es la simulación de una transmisión Bluetooth a nivel físico por medio de MATLAB Simulink. Como punto de partida se ha tomado un modelo Simulink ya obsoleto basado en el estándar 802.15‐01[1], que simula la transmisión de voz a través de un link SCO con modulación GFSK. Se han llevado a cabo una serie de cambios para actualizarlo en concordancia con la última especificación de Bluetooth[2], y se ha diseñado también una batería de pruebas para est...

  7. CAPA-Gene Products in the Haematophagous Sandfly Phlebotomus papatasi (Scopoli) - Vector for Leishmaniasis Disease

    Science.gov (United States)

    2012-01-01

    Phlebotominae, Nematocera , Diptera) are responsible for transmission of leishmaniasis and other protozoan-borne diseases in humans, and...SUPPLEMENTARY NOTES 14. ABSTRACT Sandflies (Phlebotominae, Nematocera , Diptera) are responsible for transmission of leishmaniasis and other protozoan...AGPSATTGVWFGPRLa M. domestica AGGTSGLYAFPRVa ASLFNAPRVa – AGPSATTGVWFGPRLa Delia radicum GGGGTSGLFAFPRVa AGLFAQPRLa AGPSATTGVWFGPRLa Nematocera A

  8. Control de Sustancias Agotadoras de la Capa de Ozono (SAO) en vehículos importados

    OpenAIRE

    Miguel Antonio Cano-Pérez; Marlene Castro-Naranjo; Deyvi Rodríguez-Ramírez; Déborah Romero-Ferrer

    2011-01-01

    Se aborda el estudio sobre importaciones de vehículos, realizadas en la provincia de Holguín por las entidades MOA DIESEL S.A. y UNEVOL S.A, en el año 2009, con sistemas de aire acondicionado incorporados, sin la comprobación por la Aduana, ni por los especialistas del Centro de Inspección Ambiental del Ministerio de Ciencia, Tecnología y Medio Ambiente (CITMA) acreditados al efecto, del tipo de gas refrigerante de los sistemas de climatización. Señala las partidas arancelarias de los vehícul...

  9. La formación en América de la capa social dirigente

    Directory of Open Access Journals (Sweden)

    Juan Friede

    1963-06-01

    Full Text Available Las experiencias que adquirió Castilla en la repoblación del solar patrio, a consecuencia de la Reconquista, tenían que reflejarse necesariamente en la empresa colonizadora en América. La modalidad de la "repoblación", tal como la empleada en las mesetas castellanas, mediante la ocupación por comunidades de campesinos libres de las tierras escasamente pobladas, las "behetrías", no pudo ser empleada en América.

  10. Comparative Effectiveness of CAPA and FOCUS Online: Career Assessment Systems with Undecided College Students

    Science.gov (United States)

    Betz, Nancy E.; Borgen, Fred H.

    2009-01-01

    The present study compared the effectiveness of two online career exploration systems in increasing the career decision self-efficacy and decidedness of 960 students enrolled in a program for undecided freshmen students at a large public university. Results indicated that both systems led to significant increases in career decision self-efficacy…

  11. Homo (pre) faber

    OpenAIRE

    Miguel Ángel de la Cova Morillo-Velarde

    2012-01-01

    RESUMEN En el presente número de la Revista PpA, dedicado a la vivienda prefabricada, se entrelazan dos de los campos de investigación de la arquitectura más efervescentes del último siglo: técnica y habitar. Industrialización, estandarización, modulación y seriación se confunden con el concepto de prefabricación como finas capas de un hojaldre difíciles de separar, horneadas bajo un mismo fuego que no es otro que el de responder a través de la producción reglada al alojamiento. En todos esto...

  12. Simultaneous determination of the lipoxygenase and hydroperxide lyase specificity in olive fruit pulp

    Directory of Open Access Journals (Sweden)

    Salas, Joaquín J.

    2000-06-01

    Full Text Available Olive pulp lipoxygenase regiospecificity and hydroperoxide lyase substrate specificity are important parameters in order to justify the volatile composition of olive oil. A new radiolabelling method to determine simultaneously these properties using only thin layer chromatography steps is described in the present work. The method involves incubation of an enzyme preparation from olive pulp with radiolabelled linoleate, followed by the fractionation of the resulting lipid products, previously treated with 2,4-dinitrophenyl hydrazine, on thin layer chromatography plates coated with polyethylenglycol 400. The results obtained are in agreement with previous studies carried out by other methods.La regioespecificidad de la lipoxigenasa y la especificidad del sustrato hidroperóxido liasa de pulpa de aceituna son parámetros importantes en la justificación de la composición en volátiles del aceite de oliva. En este trabajo se describe un nuevo método de marcaje radioactivo para determinar simultáneamente estas propiedades, usando solo etapas de cromatografía en capa fina. El método implica la incubación de una preparación enzimática de pulpa de aceituna con linoleato marcado, seguido del fraccionamiento de los productos lipídicos resultantes, previamente tratados con 2,4-dinitrofenil hidrazina, sobre placas de cromatografía en capa fina soportadas con polietilenglicol 400. Los resultados obtenidos están de acuerdo con estudios previos llevados a cabo con otros métodos.

  13. Revestimientos Continuos Interiores de Varias Capas con Características de Barrera de Vapor e Higroscopicidad

    OpenAIRE

    Mesquita, Carlos Alexandre Coutinho

    2013-01-01

    El trabajo realizado ha pretendido desarrollar y caracterizar una solución de revestimiento continuo interior con características de barrera de vapor e higroscopicidad. El objetivo ha sido desarrollar una solución de revestimiento continuo interior, capaz de reducir el riesgo de condensación intersticial en los cerramientos, manteniendo la capacidad de regulación de la humedad del ambiente interior. ESTUDIO DE ANTECEDENTES 1 La condensación intersticial La condensación intersticial se pro...

  14. Forecast fire damp emission in thin, steep coal bed; Prevision de Desprendimiento de Grisu en Capas Estrechas e Inclindas

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    A model to forecast fire damp emission in thin, steep coal bed, mining in advance and backfill works, has been developed and validated. The model estimates the amount of methane released towards the works, including fire damp proceeding from the actually mined seam, as well as methane coming from adjacent seams layers, depending on easy-to find parameters. Methane coming from the mined seam is determined as a function of the methane concentration in the seam and methane from adjacent seams is assessed by the degassification degree. This parameter depends also on the distance to the mined seam. The influence volume of a thin, steep mined coal bed has been determined, in order to study which seams and layers release methane towards the works. The works to develop the methane emission model were done in a coal face on Maria seam, in San Antonio mine, belonging to HUNOSA. The validation works were carried out in 24 left south seam, in the belonging to Minas de Figaredo, S. A. (Author)

  15. Caracterización de genes vinculados al crecimiento y al color de capa en la Llama (Lama glama)

    OpenAIRE

    2014-01-01

    La Llama es el Camélido doméstico más abundante de Argentina. La cría de Llamas constituye una actividad económica de gran importancia debido a que es una especie poliproductora de carne, fibra, cuero y transporte. Actualmente existe interés creciente por mejorar el rendimiento y calidad de estos productos. El estudio de genes candidatos permite vincular las variaciones de un carácter y la manera en que éste se manifiesta en el fenotipo del individuo. En ese contexto la hormona de crecimiento...

  16. Measurement of Labile Cu, Pb and Their Complexation Capa-city in Yueqing Bay in Zhejiang Province, China

    Institute of Scientific and Technical Information of China (English)

    王正方; 吕海燕; 傅和芳

    2004-01-01

    The complexation capacity of Cu and Pb and their labile and organic contents were determined separately for surface seawater samples from Yueqing Bay. The samples were prepared using Nuclepore filtration method yielding <1.0μm, <0.4μm and <0.2μm particulate water samples. Our data indicated that the <0.2μm colloidal fraction is a major carrier for distribution of copper in seawater. Affinity of Cu to marine microparticles plays an important role in the process. Pb however, tends to be absorbed by >0.2μm particles. The complexation capacity of Pb with <0.2μm particulates was smaller than that with 0.2-1.0μm particulates, and averaged 11.5 and 23.0nmol/L respectively. The results suggested that colloidal particles were responsible for the distribution and concentration of Pb in seawater.

  17. Microstructure and magnetic properties of backward extruded NdFeB ring magnets by the CAPA process

    Science.gov (United States)

    Kim, Hyoung-Tae; Kim, Yoon-Bae

    2004-06-01

    The inhomogeneity in microstructure and magnetic properties of a ring magnet prepared by backward extrusion with a current-applied pressure-assisted process has been investigated. The initial part (top part) of a ring magnet prepared by back extrusion shows a high coercivity which is comparable to the raw powder. It exhibits isotropic characteristics along the three orthogonal directions probably due to small deformation. The last part (bottom part) of the ring magnet has a a low coercivity with large grains because high current flows through the pressurized punches during the whole deformation process as to increase the temperature and grain growth. The middle part is under an appropriate deformation with short time exposure at high temperature, therefore it maintains a relatively high remanent polarization with high coercivity.

  18. Revista do Museu Paulista e(m capas: identidade e representação institucional em texto e imagem

    Directory of Open Access Journals (Sweden)

    Vera L\\u00FAcia Nagib Bittencourt

    2012-01-01

    Full Text Available This paper offers a reflection about the writing of History, based on the study of Revista do Museu Paulista's covers, noticeably during the term of its two first directors, when a certain editorial continuity was preserved. Taken as "sources", namely as historian subjects, those covers reveal evidences of practices that allow one to reconstitute, in its historic dimensions, the complex connection between the creation of the Revista, its materiality, and the reading and interpretation efforts that condition and reflect liaisons with writers and readers during the first decades of the XXth Century, from São Paulo, where it was published..

  19. Thin films and coatings deposited by vacuum techniques; Capas delgadas y recubrimientos obtenidos mediante tecnicas de vacio

    Energy Technology Data Exchange (ETDEWEB)

    Albella, J. M.; Endrino, J. L.

    2010-07-01

    This paper gives an overview of the various aspects associated with the development of coatings and thin films in all its aspects, from the preparation techniques to the technological applications. It addresses such important issues, such as the comparison of some techniques with others, or the choice of a deposition method to achieve certain characteristics in the deposited layer. (Author) 8 refs.

  20. Desarrollo del teclado virtual “Mokey” basado en gestos para personas con movilidad reducida: capa de sistema

    OpenAIRE

    López García, Marcos

    2015-01-01

    La Realidad Aumentada forma parte de múltiples proyectos de investigación desde hace varios años. La unión de la información del mundo real y la información digital ofrece un sinfín de posibilidades. Las más conocidas van orientadas a los juegos pero, gracias a ello, también se pueden implementar Interfaces Naturales. En otras palabras, conseguir que el usuario maneje un dispositivo electrónico con sus propias acciones: movimiento corporal, expresiones faciales, etc. El presente proyecto m...

  1. Glauber, Thurneisser e outros. Tecnologia química e química fina, conceitos não tão novos assim

    Directory of Open Access Journals (Sweden)

    Maar Juergen Heinrich

    2000-01-01

    Full Text Available Chemical Technology and Fine Chemicals, in the sense we understand them, go back not to Leblanc's soda production process, as many historians of Science and chemists suggest, but to the XVIIth Century, with the "technological" activities of Glauber and others; the Paracelsian Thurneisser can be seen as the first to produce "fine chemicals".

  2. Cuentos animados para la estimulación auditiva, visual y motora fina de niños y niñas

    OpenAIRE

    2013-01-01

    Informe de labores--Universidad de Costa Rica, Vicerrectoría de Acción Social, Trabajo Comunal Universitario. 2013. Para mayor información puede escribir a El taller presenta la narración de 5 historias diferentes, complementadas con sonidos, imágenes y texturas relacionados con la narración. En cada relato repasa conceptos básicos, pero necesarios para fortalecer el conocimiento de los niños (as); por ejemplo, colores, animales, objetos, amaños, sonidos, es deci...

  3. Influencia de las concentraciones de aceite y emulsionante en las propiedades reológicas de emulsiones aceite en agua del tipo salsa fina

    Directory of Open Access Journals (Sweden)

    Franco, José María

    1995-04-01

    Full Text Available The viscous and viscoelastic behaviour of food emulsions containing a mixture of egg yolk and sucrose stearate as a function of oil and sucrose stearate concentrations were studied. Oil concentrations ranged between 40- 55% w/w for emulsions containing 5% w/w sucrose stearate and sucrose ester concentrations varied between 0-10% w/w for emulsions containing 50% w/w oil. steady flow, linear oscillatory shear tests and droplet size distribution measurements were carried out. An increase in oil or emulsifier concentration produced an increase in both the steady-state viscosity and in the viscoelastic functions. The results have been explained on the basis of the relationship between the structural parameters and the rheology of the emulsions studied.

    Se ha estudiado la influencia que ejercen las concentraciones de aceite y emulsionante sobre el comportamiento viscoso y viscoelástico de emulsiones alimentarias con bajo contenido en aceite estabilizadas por una mezcla de yema de huevo y estearato de sacarosa. Se han preparado emulsiones variando la concentración de aceite entre el 40 y el 55% p/p en emulsiones con un 5% p/p en sucroéster y la concentración de sucroéster entre el 0 y el 10% p/p manteniendo un 50% p/p en aceite. Se han realizado medidas reológicas en cizalla oscilatoria dentro del intervalo de viscoelasticidad lineal, representativas de un estado imperturbado, y medidas en cizalla estacionaria, que causan una gran destrucción estructural. También se han determinado las distribuciones de tamaños de gota. Un aumento en el contenido de aceite o emulsionante produce un aumento de las funciones viscoelásticas dinámicas y de la viscosidad estacionaria. Estos resultados se explican en función de los parámetros estructurales de las emulsiones.

  4. Se necesita mayor sintonía fina entre la política fiscal y la competitividad de la economía

    OpenAIRE

    Marcelo Capello; Sebastián Alvarez

    2015-01-01

    Hacia el final de la Convertibilidad la economía argentina se hallaba en un callejón sin salida, principalmente por dos problemas: i) Baja competitividad en la producción de bienes; y ii) Inviabilidad fiscal. Si bien la competitividad de una economía no está dada sólo por el nivel del tipo de cambio real, evidentemente que el hecho de que Argentina se mantuviera once años con cambio fijo contra el dólar, mientras muchos países del mundo devaluaron en ese lapso contra dicha moneda, deterioró l...

  5. Qualidade sensorial e físico-química de uvas finas de mesa cultivadas no submédio São Francisco

    Directory of Open Access Journals (Sweden)

    Robson de Jesus Mascarenhas

    2013-06-01

    Full Text Available O objetivo deste trabalho foi avaliar uvas Vitis vinifera L. das variedades comerciais: Brasil, Benitaka, Itália e Red Globe, quanto às características físico-químicas e sensoriais. Os teores de sólidos solúveis, diâmetro e comprimento das bagas, cujos resultados apresentaram conformidade com os padrões comerciais, foram determinados. A avaliação sensorial foi realizada por meio da Análise Descritiva Quantitativa - ADQ. Foram selecionados e treinados os julgadores que, sob orientação de um líder, estabeleceram os atributos sensoriais capazes de descrever com fidedignidade as características das uvas, conforme se segue: tonalidade de cor, uniformidade de cor, aroma característico, firmeza, gosto doce, gosto amargo, gosto ácido, adstringência, sabor e qualidade global. Constatou-se que as médias obtidas nos atributos tonalidade de cor, uniformidade de cor, firmeza, sabor e qualidade global diferiram estatisticamente dentre as uvas avaliadas e, ainda, que os atributos do sabor, seguido do gosto doce e da tonalidade da cor, apresentaram as correlações mais fortes com a qualidade global, determinantes, portanto, das características sensoriais das uvas.

  6. Soldadura de aceros dual phase en chapa fina: GMAW, PAW y RSW Welding of dual phase steel sheet: GMAW, PAW and RSW

    Directory of Open Access Journals (Sweden)

    Hernán Svoboda

    2011-06-01

    Full Text Available Los aceros Dual Phase (DP han encontrado recientemente una fuerte aplicación en elementos estructurales en la industria automotriz, debido a la necesidad de disminuir peso. La soldadura de estos materiales cobra particular importancia considerando su aplicación estructural y los procesos relacionados en su fabricación. En particular la soldadura de resistencia por punto (RSW y semiautomática con alambre macizo y protección gaseosa (GMAW son ampliamente utilizados en la industria automotriz. El proceso de soldadura por plasma (PAW se caracteriza, entre los procesos de soldadura por arco, por ser el de mayor densidad de energía, presentando particular interés en aplicaciones de la industria automotriz (tailor welded blanks. El objetivo del presente trabajo fue estudiar la evolución microestructural y las propiedades de aceros DP soldados mediante los procesos RSW, GMAW y PAW. A este fin, se soldaron cuatro grados de aceros DP con resistencias mecánicas de 550, 700 y 850 MPa en espesores de 1 y 1,3 mm mediante los mencionados procesos. Se caracterizaron las microestructuras y se determinaron las propiedades mecánicas de las uniones soldadas para cada caso. Para los tres procesos se obtuvieron uniones soldadas de calidad satisfactoria. Se observó para todas las soldaduras, que en la ZAC se produce una disminución de la dureza por debajo del valor del material base, relacionada a la descomposición de la fase martensítica. Las soladuras por arco fueron las más afectadas.Dual Phase steels (DP have been used recently as an interesting option for structural elements, specialy in automotive industry, due to weight reduce requirements. Welding of these materials becomes particularly important considering their application as structural elements and the related manufacturing methods. In particular resistance spot welding (RSW and gas metal arc welding (GMAW are widely used in the automotive manufacturing. The plasma arc welding (PAW has the charateristic, within arc welding processes, to involve the highest energy density, being this parameter interesting to certain applications on automative industry (tailor welded blanks. The objective of this work is to study the microstructural evolution and properties of welded DP steels by mean of RSW, GMAW and PAW. In this regard four DP steels, with tensile strength of 550, 700 y 850 MPa and thickness of 1 and 1.3 mm, were welded by mean of mentioned welding processes. Microstructures were charaterized and mechanical properties for each weld joint were determined. For the three processes good quality welded joints were obtained. It was observed on heat affected zone (HAZ a softened zone whose hardness is below to initial base metal hardness. This softening is related to the dissolution of the martensitic phase due to thermal cycle introduced by welding. Arc welds were the most affected.

  7. Identificação online de sinais baseada em calorimetria de altas energias e fina segmentação

    CERN Document Server

    Ciodaro, T; Cerqueira, A

    The ATLAS experiment operates in the environment of the large hadron collider, the LHC, located at CERN, Switzerland. LHC accelerates bunches of protons in opposite directions and collide them in specific collision points every 25 ns, reaching up to 14 TeV of energy at the center of mass. Through these collisions, it is possible to probe deep into matter and explore interesting physical process in a way which was never seen by science. As much of the produced information is related to uninteresting physics, it was implemented an online trigger system to select possible events from the interesting physical channels produced by LHC. In particular, the first level trigger uses compact information from both calorimeters and muon chambers for a fast event selection. The other high-level triggers access the full detector resolution, yielding high performance algorithms for particle identification. The muon chambers, though, can be significantly degraded by the strong radioactive environment at the cavern where ATLA...

  8. Análisis estructural de la porosidad efectiva en el horizonte tobas finas del yacimiento Pina, Ciego de Ávila

    OpenAIRE

    José Q. Cuador-Gil; Arelys Quintero-Silverio

    2000-01-01

    El análisis del comportamiento espacial de los parámetros que intervienen en el cálculo de reservas en un yacimiento petrolífero es de particular importancia para la aplicación de los métodos geoestadísticos. Estos métodos recién han sido introducidos en la industria del petróleo, lo cual ha reportado resultados exitosos; sin embargo, en Cuba no son ampliamente usados. Ellos tienen como objetivo revelar las características de variabilidad y correlación espacial del fenómeno y, a partir de ést...

  9. PRODUCCIÓN DE HOJARASCA FINA EN BOSQUES ALTO ANDINOS DE ANTIOQUIA, COLOMBIA FINE LITTER PRODUCTION IN HIGH ANDEAN FORESTS FROM ANTIOQUIA, COLOMBIA

    Directory of Open Access Journals (Sweden)

    Claudia Marcela Zapata Duque

    2007-06-01

    Full Text Available En bosques montanos naturales de Quercus humboldtii y reforestados (Pinus patula y Cupressus lusitanica de la región de Piedras Blancas, Antioquia (Colombia, fue evaluada la producción de hojarasca por un periodo de 2 años. Se utilizaron trampas de hojarasca con el fin de recoger el material desprendido del dosel para su posterior separación en fracciones y pesado respectivo. El promedio de caída de hojarasca anual para Q. humboldtii, P. patula y C. lusitanica fue de 7877,20; 8362,47 y 3725,97 kg ha-1año-1 respectivamente; siendo la fracción foliar la que mayor participación tuvo en la producción total. Mediante análisis de regresión lineal múltiple se ajustaron modelos de producción de hojarasca según fracciones por cobertura en función de diferentes variables hidrológicas, tales como la intensidad y la cantidad de lluvia del período simultáneo a la recolección de la hojarasca o inmediatamente anterior.Litter production was measured over two years in a montane oak forest (Quercus humboldtii and in pine (Pinus patula and cypress (Cupressus lusitanica plantations in Piedras Blancas, Antioquia ( Colombia . Litter traps were used in order to collect litterfall to be subsequently separated into fractions and weighed. Annual mean litterfall for Q. humboldtii, P. patula and C. lusitanica was of 7877,20; 8362,47 and 3725,97 kg ha-1year-1 respectively; being the leaf fraction of highest participation in total production. Multiple linear regression models were used to fit litter production for each fraction and forest cover as a function of different hydrological variables such as intensity and quantity of precipitation, both during the period when the leaf litter was collected and immediately preceding one.

  10. An ICF-based education programme in amputation rehabilitation for medical residents in the Netherlands

    NARCIS (Netherlands)

    Geertzen, Jan H. B.; Rommers, G. M.; Dekker, Rienk

    2011-01-01

    Background and Aim: Education programmes of the International Society for Prosthetics and Orthotics (ISPO) are directed primarily at prosthetists and orthotists. In a multidisciplinary setting, greater attention should be given to other professionals working in the field of amputation, prosthetics a

  11. Meeting the criteria of a nursing diagnosis classification: Evaluation of ICNP, ICF, NANDA and ZEFP.

    NARCIS (Netherlands)

    Müller-Staub, M.; Lavin, M.A.; Needham, I.; Achterberg, T. van

    2007-01-01

    BACKGROUND: Few studies described nursing diagnosis classification criteria and how classifications meet these criteria. OBJECTIVES: The purpose was to identify criteria for nursing diagnosis classifications and to assess how these criteria are met by different classifications. DESIGN/METHODS: First

  12. Automated fabrication, characterization and transport of ICF pellets. Final report, March 1, 1979-October 31, 1980

    Energy Technology Data Exchange (ETDEWEB)

    Clifford, D W; Boyd, B A; Lilienkamp, R H

    1980-12-01

    The near-term objectives of the contract were threefold: (1) evaluate techniques for the production of frozen hydrogen microspheres and demonstrate concepts for coating them; (2) develop and demonstrate an optical characterization system which could lead to automated pellet inspection; and (3) develop and demonstrate a preliminary electrostatic pellet transport control system. This report describes the equipment assembled for these experiments and the results obtained.

  13. A Population Survey in Italy Based on the ICF Classification: Recognizing Persons with Severe Disability

    Directory of Open Access Journals (Sweden)

    Matilde Leonardi

    2012-01-01

    Full Text Available Aim of this paper is to describe functioning of subjects with “severe disability” collected with a protocol based on the International Classification of Functioning, Disability, and Health. It included sections on body functions and structures (BF and BS, activities and participation (A&P, and environmental factors (EF. In A&P, performance without personal support (WPS was added to standard capacity and performance. Persons with severe disability were those reporting a number of very severe/complete problems in BF or in A&P-capacity superior to mean + 1SD. Correlations between BF and A&P and differences between capacity, performance-WPS, and performance were assessed with Spearman's coefficient. Out of 1051, 200 subjects were considered as severely disabled. Mild to moderate correlations between BF and A&P were reported (between 0.148 and 0.394 when the full range of impairments/limitations was taken into account; between 0.198 and 0.285 when only the severe impairments/limitations were taken into account; performance-WPS was less similar to performance than to capacity. Our approach enabled identifying subjects with “severe disability” and separating the effect of personal support from that of devices, policies, and service provision.

  14. A population survey in Italy based on the ICF classification: recognizing persons with severe disability.

    Science.gov (United States)

    Leonardi, Matilde; Martinuzzi, Andrea; Meucci, Paolo; Sala, Marina; Russo, Emanuela; Buffoni, Mara; Raggi, Alberto

    2012-01-01

    Aim of this paper is to describe functioning of subjects with "severe disability" collected with a protocol based on the International Classification of Functioning, Disability, and Health. It included sections on body functions and structures (BF and BS), activities and participation (A&P), and environmental factors (EF). In A&P, performance without personal support (WPS) was added to standard capacity and performance. Persons with severe disability were those reporting a number of very severe/complete problems in BF or in A&P-capacity superior to mean + 1SD. Correlations between BF and A&P and differences between capacity, performance-WPS, and performance were assessed with Spearman's coefficient. Out of 1051, 200 subjects were considered as severely disabled. Mild to moderate correlations between BF and A&P were reported (between 0.148 and 0.394 when the full range of impairments/limitations was taken into account; between 0.198 and 0.285 when only the severe impairments/limitations were taken into account); performance-WPS was less similar to performance than to capacity. Our approach enabled identifying subjects with "severe disability" and separating the effect of personal support from that of devices, policies, and service provision.

  15. Quantitative Analysis of Backlit Shadowgraphy as a Diagnostic of Hydrogen Ice Surface Quality in ICF Capsules

    Energy Technology Data Exchange (ETDEWEB)

    Koch, J.A.; Sater, J.; Bernat, T.; Bittner, D.; Collins, G.; Hammel, B; Lee, Y.; Mackinnon, A.

    1999-10-26

    This document presents the Integrated Safety Management System (ISMS) Description for the Superblock non-reactor nuclear facilities-Tritium Facility (Building 331), Plutonium Facility (Building 332), and Building 334--at the Lawrence Livermore National Laboratory. Building 332 is a Nuclear Hazard Category 2 facility, while Buildings 331 and 334 are Category 3 facilities in accordance with DOE STD-1027, DOE STD-3009, and DOE Order 5480.23. In implementing the Superblock ISMS Description, a graded approach is used--the Category 2 nuclear facility description provides more detail than those for the Category 3 nuclear facilities.

  16. Monitoring and Prognosis System Based on the ICF for People with Traumatic Brain Injury

    Directory of Open Access Journals (Sweden)

    Laia Subirats

    2015-08-01

    Full Text Available The objective of this research is to provide a standardized platform to monitor and predict indicators of people with traumatic brain injury using the International Classification of Functioning, Disability and Health, and analyze its potential benefits for people with disabilities, health centers and administrations. We developed a platform that allows automatic standardization and automatic graphical representations of indicators of the status of individuals and populations. We used data from 730 people with acquired brain injury performing periodic comprehensive evaluations in the years 2006–2013. Health professionals noted that the use of color-coded graphical representation is useful for quickly diagnose failures, limitations or restrictions in rehabilitation. The prognosis system achieves 41% of accuracy and sensitivity in the prediction of emotional functions, and 48% of accuracy and sensitivity in the prediction of executive functions. This monitoring and prognosis system has the potential to: (1 save costs and time, (2 provide more information to make decisions, (3 promote interoperability, (4 facilitate joint decision-making, and (5 improve policies of socioeconomic evaluation of the burden of disease. Professionals found the monitoring system useful because it generates a more comprehensive understanding of health oriented to the profile of the patients, instead of their diseases and injuries.

  17. A reduced model for the ICF gamma-ray reaction history diagnostic

    Energy Technology Data Exchange (ETDEWEB)

    Schmitt, Mark J [Los Alamos National Laboratory; Wilson, Douglas C [Los Alamos National Laboratory; Hoffman, Nelson M [Los Alamos National Laboratory; Langenbrunner, Jamie R [Los Alamos National Laboratory; Hermann, H W [Los Alamos National Laboratory; Kim, Y H [Los Alamos National Laboratory; Young, C S [Los Alamos National Laboratory; Evans, S C [Los Alamos National Laboratory; Cerjan, C J [LLNL; Stoeffl, Wolfgang [LLNL; Munro, D H [LLNL; Dauffy, L S [LLNL; Miller, K M [LIVERMORE; Horsfield, C J [AWE; Rubery, M S [AWE

    2009-01-01

    An analytic model for the gamma reaction history (GRH) diagnostic to be fielded on the National Ignition Facility is described. The application of the GRH diagnostic for the measurement of capsule rho-R during burn using 4.4 MeV carbon gamma rays is demonstrated by simulation.

  18. Communication performance of children with Down Syndrome: An ICF-CY based multiple case study

    NARCIS (Netherlands)

    Deckers, S.R.J.M.; Zaalen, Y. van; Stoep, J.M.G.M.; Balkom, L.J.M. van; Verhoeven, L.T.W.

    2016-01-01

    Enhancing communication performance skills may help children with Down Syndrome (DS) to expand their opportunities for participation in daily life. It is a clinical challenge for speech-language pathologists (SLP) to disentangle various mechanisms that contribute to the language and communication pr

  19. A reduced model for the ICF Gamma-Ray reaction history diagnostic

    Science.gov (United States)

    Schmitt, M. J.; Wilson, D. C.; Hoffman, N. M.; Langenbrunner, J. R.; Herrmann, H. W.; Kim, Y. H.; Young, C. S.; Evans, S. C.; Cerjan, C. J.; Stoeffl, Wolfgang; Munro, D. H.; Dauffy, L. S.; Miller, K. M.; Horsfield, C. J.; Rubery, M. S.

    2010-08-01

    An analytic model for the gamma reaction history (GRH) diagnostic to be fielded on the National Ignition Facility is described. The application of the GRH diagnostic for the measurement of capsule rho-R during burn using 4.4 MeV carbon gamma rays is demonstrated by simulation.

  20. ICF linked Dutch physiotherapy guidelines concerning initial assessment, treatment and evaluation in hip and knee osteoarthritis.

    NARCIS (Netherlands)

    Peter, W.; Jansen, M.J.; Hurkmans, E.J.; Bloo, H.; Dekker-Bakker, L.M.M.C.J.; Dilling, R.G.; Hilberdink, W.K.H.A.; Kersten-Smit, C.; Rooij, M. de; Veenhof, C.; Vermeulen, E.M.; Vos, I. de; Schoones, J.W.; Vliet Vlieland, T.P.

    2011-01-01

    Purpose: In 2001 the Royal Dutch Society for Physical Therapy (KNGF) Guideline for hip and knee osteoarthritis (HKOA) was developed. Since then, many scientific papers on physical therapy interventions as well as national and international guidelines were published. Relevance: An update of the physi

  1. LLNL ICF highlights for the period of July 14, 2016 to July 20, 2016

    Energy Technology Data Exchange (ETDEWEB)

    Herrmann, M. C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-07-25

    LLNL executed two HED Fused Silica Dome experiments as part of the complex hydrodynamics campaign on NIF. These shots assessed breakout times and velocities of shocks at five different angles separated by 45°. Each target looked at three different locations on the capsule measuring the shock breakout time and speed. The experiments used a significantly larger hohlraum and energy in the laser pulse than in previous complex hydrodynamics hohlraums. LLNL conducted a shot on NIF to continue developing a high pressure drive platform for Rayleigh-Taylor strength experiments. VISAR was the primary diagnostic and returned good quality data.

  2. Suitability of Different Polyimide Capsule Materials for Use as ICF Targets

    Energy Technology Data Exchange (ETDEWEB)

    Knight, A.K.; Tsai, F.-Y.; Bonino, M.J.; Harding, D.R.

    2004-03-15

    OAK-B135 Previous research efforts to fabricate direct-drive polyimide shells have focused on identifying processes that maximize the mechanical and permeation properties of the polyimide material. A strong correlation exists between these properties and the processing conditions, which is ascribed to the crystallinity and segmental mobility of the polyimide chains. This correlation, together with the range of properties that have been demonstrated, will be reported. For example, the permeability of biaxially strained polyimide is three orders of magnitude higher than that of the normal Kapton formulation, decreasing the necessary fill time from 320 h to 0.66 h for an OMEGA target. Current research efforts focus on improving the smoothness of polyimide shells. The approach is to model the effect of different configurations of the equipment and processing parameters on the impinging mass flux of reactants onto the shell substrates. This is done using both computational fluid dynamics (FLUENT) and Monte Carlo codes to cover the relevant pressure regimes. Both molecular gas dynamics and surface chemistry are included in the models. These models are then cross-referenced to the measured smoothness of the shells.

  3. Monitoring and Prognosis System Based on the ICF for People with Traumatic Brain Injury.

    Science.gov (United States)

    Subirats, Laia; Lopez-Blazquez, Raquel; Ceccaroni, Luigi; Gifre, Mariona; Miralles, Felip; García-Rudolph, Alejandro; Tormos, Jose María

    2015-08-18

    The objective of this research is to provide a standardized platform to monitor and predict indicators of people with traumatic brain injury using the International Classification of Functioning, Disability and Health, and analyze its potential benefits for people with disabilities, health centers and administrations. We developed a platform that allows automatic standardization and automatic graphical representations of indicators of the status of individuals and populations. We used data from 730 people with acquired brain injury performing periodic comprehensive evaluations in the years 2006-2013. Health professionals noted that the use of color-coded graphical representation is useful for quickly diagnose failures, limitations or restrictions in rehabilitation. The prognosis system achieves 41% of accuracy and sensitivity in the prediction of emotional functions, and 48% of accuracy and sensitivity in the prediction of executive functions. This monitoring and prognosis system has the potential to: (1) save costs and time, (2) provide more information to make decisions, (3) promote interoperability, (4) facilitate joint decision-making, and (5) improve policies of socioeconomic evaluation of the burden of disease. Professionals found the monitoring system useful because it generates a more comprehensive understanding of health oriented to the profile of the patients, instead of their diseases and injuries.

  4. Some Thoughts on the Role of non-LTE Physics in ICF

    Energy Technology Data Exchange (ETDEWEB)

    Colvin, J. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-03-07

    An effort to develop sub-critical-density high-Z metal-doped and pure metal foams as laser-driven x-ray sources is described. The main idea is that the laser beams preferentially heat the electrons, and if the plasma is sufficiently low density so that the heating rate is greater than the equilibration rate via electron-ion collisions, then the electron temperature in the plasma is much greater than the ion temperature as long as the laser is on. In such a situation the plasma is not in local thermal equilibrium (LTE), it heats supersonically and volumetrically, and the conversion efficiency of laser beam energy to multi-keV L-shell and K-shell radiation is much higher than what it would be in LTE plasma.

  5. Electron Generation and Transport in Intense Relativistic Laser-Plasma Interactions Relevant to Fast Ignition ICF

    Energy Technology Data Exchange (ETDEWEB)

    Ma, Tammy Yee Wing [Univ. of California, San Diego, CA (United States)

    2010-01-01

    The reentrant cone approach to Fast Ignition, an advanced Inertial Confinement Fusion scheme, remains one of the most attractive because of the potential to efficiently collect and guide the laser light into the cone tip and direct energetic electrons into the high density core of the fuel. However, in the presence of a preformed plasma, the laser energy is largely absorbed before it can reach the cone tip. Full scale fast ignition laser systems are envisioned to have prepulses ranging between 100 mJ to 1 J. A few of the imperative issues facing fast ignition, then, are the conversion efficiency with which the laser light is converted to hot electrons, the subsequent transport characteristics of those electrons, and requirements for maximum allowable prepulse this may put on the laser system. This dissertation examines the laser-to-fast electron conversion efficiency scaling with prepulse for cone-guided fast ignition. Work in developing an extreme ultraviolet imager diagnostic for the temperature measurements of electron-heated targets, as well as the validation of the use of a thin wire for simultaneous determination of electron number density and electron temperature will be discussed.

  6. Past and future use of the ICF (former ICIDH) by nursing and allied health professionals.

    NARCIS (Netherlands)

    Heerkens, Y.F.; Brug, Y. van der; Napel, H.M.T.D. ten; Ravensberg, C.D. van

    2003-01-01

    PURPOSE: This study describes the use of the ICIDH by allied health professionals and the nursing professions in The Netherlands. It is an example for showing how in recent years the application of the ICIDH has developed within professions. The data elements of patient descriptors documented by nur

  7. Multiresolution Analysis Techniques to Isolate, Detect and Characterize Morphologically Diverse Features of Structured ICF Capsule Implosions

    CERN Document Server

    Afeyan, Bedros; Jones, Peter; Starck, Jean Luc; Herrmann, Mark

    2012-01-01

    In order to capture just how nonuniform and degraded the symmetry may become of an imploding inertial confinement fusion capsule one may resort to the analysis of high energy X ray point projection backlighting generated radiographs. Here we show new results for such images by using methods of modern harmonic analysis which involve different families of wavelets, curvelets and WaSP (wavelet square partition) functions from geometric measure theory. Three different methods of isolating morphologically diverse features are suggested together with statistical means of quantifying their content for the purposes of comparing the same implosion at different times, to simulations and to different implosion images.

  8. Turbulent mix or ion diffusion? Hypothesis testing in ICF capsule implosions

    Science.gov (United States)

    Hoffman, N. M.; Zimmerman, G. B.; Vander Wiel, S. A.; Herrmann, H. W.; Kim, Y. H.

    2016-10-01

    Turbulent mixing at a contact surface combines materials that are initially separated across the contact. While the mixing layer may contain the initially separate materials (each assumed to be composed of a number of distinct ion species) in a range of concentrations, from zero to 100%, the concentration of individual ion species within each material, relative to one another, is not altered by turbulent mixing alone. Ion diffusion likewise causes mixing at a contact, but does alter the relative concentration of ion species within each material, since the relative diffusivity of ions, in a fixed background plasma, varies as A 1 / 2/Z2. Recent hydrodynamically equivalent capsule implosions allow a test of the influence of these processes on observed capsule behavior. We use numerical simulations and hypothesis-testing methods to show quantitatively that turbulent mixing with ion diffusion is a better explanation of observed behavior than turbulent mixing alone (subject to the assumptions inherent in the computational models of these processes.) Research supported by US DOE under contract DE-AC52-06NA25396.

  9. Kinetic study of run-away burn in ICF capsule using a quasi-1D model

    Science.gov (United States)

    Huang, Chengkun; Molvig, K.; Albright, B. J.; Dodd, E. S.; Hoffman, N. M.; Vold, E. L.; Kagan, G.

    2016-10-01

    The effect of reduced fusion reactivity resulting from the loss of fuel ions in the Gamow peak in the ignition, run-away burn and disassembly stages of an inertial confinement fusion D-T capsule is investigated with a quasi-1D hybrid model that includes kinetic ions, fluid electrons and Planckian radiation photons. The fuel ion loss through the Knudsen effect at the fuel-pusher interface is accounted for by a local-loss model developed in Molvig et al.. The tail refilling and relaxation of the fuel ion distribution are evolved with a nonlinear Fokker-Planck solver. The Krokhin & Rozanov model is used for the finite alpha range beyond the fuel region, while alpha heating to the fuel ions and the fluid electrons is modeled kinetically. For an energetic pusher (40kJ), the simulation shows that the reduced fusion reactivity can lead to substantially lower ion temperature during run-away burn, while the final yield decreases more modestly. Possible improvements to the present model, including the non-Planckian radiation emission and alpha-driven fuel disassembly, are discussed. Work performed under the auspices of the U.S. DOE by the LANS, LLC, Los Alamos National Laboratory under Contract No. DE-AC52-06NA25396. Work supported by the ASC TBI project at LANL.

  10. Complicated Laser Pulse Generation With Pulse Stacking for D-D ICF

    Institute of Scientific and Technical Information of China (English)

    GAO; Zhi-xing; WANG; Lei-jian; LU; Ze; ZHANG; Hai-feng

    2012-01-01

    <正>For direct drive fusion, a pre-distorted pulse with the complicated temporal shape is necessary. It is generally accepted that the pulse for shock ignition should begin with a low energy pre-pulse spike (picket) followed by a long (about 10 ns) low intensity foot pulse, which ramps up to an intermediate pedestal (compression pulse) and ends with a short high intensity spike.

  11. Stroke Patients Communicating Their Healthcare Needs in Hospital: A Study within the ICF Framework

    Science.gov (United States)

    O'Halloran, Robyn; Worrall, Linda; Hickson, Louise

    2012-01-01

    Background: Previous research has identified that many patients admitted into acute hospital stroke units have communication-related impairments such as hearing, vision, speech, language and/or cognitive communicative impairment. However, no research has identified how many patients in acute hospital stroke units have difficulty actually…

  12. Environmental needs in childhood disability analysed by the WHO ICF, Child and Youth Version

    DEFF Research Database (Denmark)

    Illum, Niels Ove; Bonderup, Mette; Gradel, Kim Oren

    2016-01-01

    influences through interviews in their own homes. RESULTS: Of the 367 invited parents, 332 (90.5%) participated, providing data on children with spina bifida, spinal muscular atrophy, muscular disorders, cerebral palsy, visual impairments, hearing impairments, mental disability and disabilities following...

  13. Neutron, electron and photon transport in ICF tragets in direct and fast ignition

    Directory of Open Access Journals (Sweden)

    A. Parvazian

    2005-12-01

    Full Text Available Fusion energy due to inertial confinement has progressed in the last few decades. In order to increase energy efficiency in this method various designs have been presented. The standard scheme for direct ignition and fast ignition fuel targets are considered. Neutrons, electrons and photons transport in targets containing different combinations of Li and Be are calculated in both direct and fast ignition schemes. To compress spherical multilayer targets having fuel in the central part, they are irradiated by laser or heavy ion beams. Neutrons energy deposition in the target is considered using Monte Carlo method code MCNP. A significant amount of neutrons energy is deposited in the target which resulted in growing fusion reactions rates. It is found that Beryllium compared to Lithium is more important. In an introductory consideration of relativistic electron beam transport into central part of a fast ignition target, we have calculated electron energy deposition in highly dense D-T fuel and Beryllium layer of the target. It has been concluded that a fast ignition scheme is preferred to direct ignition because of the absence of hydrodynamic instability.

  14. Capsule Ablator Inflight Performance Measurements Via Streaked Radiography Of ICF Implosions On The NIF*

    Science.gov (United States)

    Dewald, E. L.; Tommasini, R.; Mackinnon, A.; MacPhee, A.; Meezan, N.; Olson, R.; Hicks, D.; LePape, S.; Izumi, N.; Fournier, K.; Barrios, M. A.; Ross, S.; Pak, A.; Döppner, T.; Kalantar, D.; Opachich, K.; Rygg, R.; Bradley, D.; Bell, P.; Hamza, A.; Dzenitis, B.; Landen, O. L.; MacGowan, B.; LaFortune, K.; Widmayer, C.; Van Wonterghem, B.; Kilkenny, J.; Edwards, M. J.; Atherton, J.; Moses, E. I.

    2016-03-01

    Streaked 1-dimensional (slit imaging) radiography of 1.1 mm radius capsules in ignition hohlraums was recently introduced on the National Ignition Facility (NIF) and gives an inflight continuous record of capsule ablator implosion velocities, shell thickness and remaining mass in the last 3-5 ns before peak implosion time. The high quality data delivers good accuracy in implosion metrics that meets our requirements for ignition and agrees with recently introduced 2-dimensional pinhole radiography. Calculations match measured trajectory across various capsule designs and laser drives when the peak laser power is reduced by 20%. Furthermore, calculations matching measured trajectories give also good agreement in ablator shell thickness and remaining mass.

  15. Sedimentos arcillosos en un suelo del valle inferior del río Colorado (Argentina Clay sediments in a soil of the lower Colorado river valley (Argentina

    Directory of Open Access Journals (Sweden)

    Norman Peinemann

    2008-12-01

    Full Text Available Se describe la presencia de capas sedimentarias ricas en minerales de arcilla en un subsuelo del valle inferior del río Colorado por su importancia para el régimen hídrico de suelos bajo riego. Difractogramas de rayos X efectuados sobre la fracción arcilla fina de estos sedimentos revelaron que está compuesta por smectitas con muy buena cristalización. La caracterización fisicoquímica del perfil de suelo mostró que el fuerte incremento de minerales de arcilla en el subsuelo estuvo vinculado con un aumento de pH y PSI y en consecuencia una marcada disminución en la conductividad hidráulica, motivo por el cual la eventual presencia de estas capas sedimentarias debe ser muy tenida en cuenta en la programación de las prácticas de riego para evitar el posible deterioro de los suelos.The presence of sedimentary clay layers in subsoils of the lower Colorado river valley are described due to their impact on the water balance of soils under irrigation. X-ray difractograms of the fine clay fraction of these sediments show that they are composed of smectites with a very good crystallization. The physicochemical characterization of the soil profile indicates that the abrupt increase of clay minerals was associated with high pH and ESP values as well as a sharp decrease in hydraulic conductivity. Therefore, the presence of sedimentary clay layers in soils has to be considered when planning irrigation practices to avoid soil degradation.

  16. Neuropeptides in Heteroptera: Identification of allatotropin-related peptide and tachykinin-related peptides using MALDI-TOF mass spectrometry

    Science.gov (United States)

    Recently, the peptidomic analysis of neuropeptides from the retrocerebral complex and abdominal perisympathetic organs of polyphagous stinkbugs (Pentatomidae) revealed the group-specific sequences of pyrokinins, CAPA peptides (CAPA-periviscerokinins/PVKs and CAPA-pyrokinin), myosuppressin, corazonin...

  17. ICF-CY理念下特殊学校开展适应体育课程的思考%Adaptive Sports Course in Special Schools under Theory of ICF-CY

    Institute of Scientific and Technical Information of China (English)

    陈钢; 王国祥

    2016-01-01

    本文在《国际功能、残疾和健康分类》(儿童和青少年版)理论视野下,重新诠释了适应体育在特殊儿童康复教育中的作用与意义,提出适应体育课程的理念和模块,为特殊学校开展适应体育课程教学提供理论参考。%In this paper, the role and significance of adaptive sports on rehabilitation education of special children were redefined, and the concept and modules of adaptive sports course were introduced, in order to provide a theoretical reference for adaptive sports course of the special school under the theory of International Classification of Functioning, Disability and Health for Children and Youth.

  18. Procesado y propiedades de impacto de materiales compuestos laminados de base hierro

    Directory of Open Access Journals (Sweden)

    Carreño, F.

    2001-04-01

    Full Text Available A seven layers steel based laminated composite (four ultra-high carbon steel, UHCS, layers and three mild steel, MS, layers has been processed by rolling bonding and its microstructure and impact properties have been studied. Suitable parameters of temperature and thickness reduction were selected to obtain a finer microstructure relative to the original material components. This finer microstructure induces improved mechanical properties. Charpy impact tests values in both "crack arrester" and "crack divider" orientations improve the values of the UHCS constituent material. Furthermore, the crack arrester orientation value exceed that of the MS material. The delamination, which is controlled by interface bonding, plays a key role deflecting the crack, absorbing energy and imposing the nucleation of new cracks in the next material layer.

    Se ha procesado un material compuesto laminado de base hierro, de 7 capas alternas de dos aceros diferentes (cuatro capas de acero de ultra-alto contenido en carbono, AUAC, y tres de acero suave, AS, mediante unión por laminación y se ha estudiado su microestructura y propiedades de impacto. Se eligieron los parámetros adecuados de temperatura y de reducción de espesor para obtener una microestructura más fina que la de los aceros constituyentes originales, lo que induce una mejora en las propiedades mecánicas. Los valores de energía absorbida en el ensayo Charpy, tanto en la dirección "en paralelo" como "en serie", han mejorado sustancialmente el valor asociado al AU AC monolítico. Además, el valor obtenido en la dirección "en serie" es superior al del AS. Se observa que la delaminación, que depende de la unión de las intercaras, juega un papel importante en la deflexión de las fisuras, absorbiendo energía e imponiendo sucesivas nucleaciones de grietas en las siguientes capas.

  19. Estudio de correlación entre la capa de fibras nerviosas peripapilar y macular y el campo visual en pacientes con glaucoma

    OpenAIRE

    2013-01-01

    El glaucoma es una enfermedad crónica y progresiva que cursa con una pérdida irreversible y permanente de las células ganglionares de la retina que, sin el diagnóstico y tratamientos adecuados, puede conducir a la ceguera. Se estima que el glaucoma, actualmente, afecta a más de 66 millones de personas en el mundo y, debido a la repercusión socioeconómica que ello acarrea, las mejoras en el conocimiento del comportamiento de esta enfermedad conllevarían una disminución del número de paci...

  20. Potencialidad probiótica de lactobacilos con capa S : Estudios sobre la inocuidad, efecto antimicrobiano y capacidad inmunomodulatoria de Lactobacillus kefiri

    OpenAIRE

    Carasi, Paula

    2014-01-01

    El tracto gastrointestinal de los mamíferos contiene una gran cantidad de microorganismos, microbiota, con los que se establece una relación simbiótica. Los desbalances de la misma, disbiosis, tienen consecuencias nocivas para el huésped y puede contribuir al desarrollo de enfermedades inflamatorias intestinales. El uso de microorganismos probióticos es una de las estrategias que se encuentran en desarrollo para intentar restaurarla o fortalecerla. El Kefir es un alimento descripto...

  1. APROXIMACIÓN NO LINEAL AL MODELO DE OVERSHOOTING USANDO REDES NEURONALES MULTlCAPA PARA EL TIPO DE CAMBIO DÓLAR-PESO

    Directory of Open Access Journals (Sweden)

    Jaime Villamil

    2009-06-01

    Full Text Available Desde los años setenta muchos trabajos han intentado elaborar una sustentación empírica de algunos modelos que ofrecieron una explicación lineal de la dinámica de la tasa de cambio de un país, entre ellos el de Dornbusch. Hasta el momento ninguno ha sido concluyente y la caminata aleatoria es considerada como el mejor modelo al que puede ajustarse. De Grauwe ha mostrado que, con la presencia de relaciones no-lineales y heterogeneidad de expectativas de los especuladores, el tipo de cambio puede tener un comportamiento aparentemente aleatorio, pero con explicación determinista. Este trabajo presenta el modelo de Dornbusch en la versión no lineal propuesta por De Grauwe y Dewachter (1993, y una aproximación usando redes neuronales multicapa aplicadas al caso del dólar/peso (USD/COP.

  2. Demostración del ingreso del virus de la rabia a la corteza cerebral a través de las neuronas piramidales de la capa V

    Directory of Open Access Journals (Sweden)

    Hernán J. Pimienta J.

    2005-03-01

    Full Text Available En condiciones naturales el virus de la rabia (VR penetra en la piel o los músculos, con la saliva unyectada por un animal infectado y entra en contacto con receptores localizados en el sistema nervioso periférico.

  3. Turbulent Characterization of atmospheric surface layer over non-homogeneous terrain; Caracterizacion turbulenta de la capa superficial atmosferica en un terreno no homogeneo

    Energy Technology Data Exchange (ETDEWEB)

    Artinano Rodriguez de Torres, B.

    1989-07-01

    About 15000 wind and temperature profiles from a 100 m tower located in CEDER (Soria, Spain) have been analyzed. Using profiles in close neutral conditions, two main parameters of surface layer were obtained. Results show a great dependence of these parameters (Z{sub 0} roughness length and u friction velocity) on flow conditions and terrain (tinctures. Difficulty finding neutral conditions in this type of terrain (gently rolling and scattered bush) and in this latitude , is also remarkable. (Author) 91 refs.

  4. Investigation for the improvement of starting-up; Investigacion para la Mejora del Arranque con Explosivos en los Talleres de Sutirage en Capas Grisuosas

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    Win this investigation it is intended to develop new techniques and blasting procedures for sub level caving in underground coal mines, so that technical and economical results reached to date, including the safety aspects, could be improved. Concretely it is intended: - To optimise blasting procedures, itemizing in each situation through adequate shot designs, and - To develop some confinement techniques of the explosive that permits to improve its efficiency preserving safety against fire damp and coal powder. Following recommendations concerning the current permitted explosives and fittings utilisation in caving shots, are obtained. - Types of Explosive: The most recommendable explosive in this type of blasts is the Type III (20 SR). - Diameters of cartridges: It is recommended the use of this explosive in diameters of 32 or higher. - Permitted detonating cord: The use of the cord is considered essential with explosives of 26 mm, and highly recommendable with any permitted explosive. - Permitted detonators: It has not been verified any difference using one or two detonators in the blasting charge. - Total charge in the borehole: with regard to this item, following considerations must be settled: 1. It has been assayed the explosive Type III in load densities greater (1350 g/m) than the currently used (750 g/m) or (1000 g/m), corresponding to continuous explosive load in cartridges of 36, 26 and 32 mm, respectively. 2. Considering tests with detonating cord only, no ignition took place in the tests of coal mortar with slot. 3. Charges up to 1600 grams of explosive by ton of coal have been tried, what would surpass in more than six times the specific regular charges used in different exploitations. 4. It does not exist any study that demonstrate the influence of the length of the load with the possibility of ignition by blowouts, or intermediate nude charges in the borehole. 5. The possibility of obtaining a nude detonation of explosive in caving greater than 1,6 kg, quality tested here, is very low. (Author)

  5. Testing of a new mining system performance at narrow coal bed; Ensayo de un sistema de arranque con cepillo mediante accionamiento hidraulico para capas estrechas de carbon

    Energy Technology Data Exchange (ETDEWEB)

    1999-09-01

    This researching project had the aim of: Testing a new mining system performance at narrow coal bed, which uses plough equipment with hydraulic driving devices. Minimising driving power group size to avoid problems regarding with the wall mining-heading transition, decreasing the needed room to house it and thus, simplifying wall mining edge support. The expected goals were: Take advantage of hydraulic driving devices to obtain a good efficiency with a variable and discontinuous load, but without loosing the electric driving devices advantages, consisting on increase driving torque, being the engine blocked Lengthen the mechanical equipment life (chains, driving sprockets, etc) Reach an economic production rate Researching project was developed in El Bierzo basin (leon, Spain), in Grupo Ampliacion, a mining group belonged to Viloria Hnos, S. A. (Author)

  6. The use of coal mining wastes in building road beds; Utilizacion de los Esteriles del Carbon como Materiales para Capas de Firmes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This project was aimed at carrying out a study in order to determine the nature and characteristics of coal mining wastes for its possible use in building road beds and to establish the acceptance, implementation and quality control criteria, which can be included in the Spanish General Technical Standard of Road and Bridges Works (PG-3). With that aim, six types of coal mining wastes were selected out of an inventory and several tests were conducted and following the results, the most appropriate coal mining wastes, the acceptance limits and the quality control tests to be applied to the materials obtained from coal mining wastes to road beds were established. A grinding and classification plant was designed in order to obtain the necessary granular materials for conducting real scale compaction tests in road stages. Several types of coal mining wastes were tested: red, black, treated (in the above mentioned plant) untreated, with different bed thickness and runs in the compactors. Likewise, laboratory tests were carried out on black and red coal mining wastes by adding binder materials. The results proved that coal mining wastes can be used as granular material for building different road beds, such as bound with cement, gravel-emulsion or on their own. As a result of this study 53,000 tons of black coal mining wastes mixed with 6% of cement as binder were used for building a 5 km stage of the Highway Oviedo-Mieres, as well as 16,000 tons of red coal mining wastes in the Ujo-Caborana road, which is still being used in the works carried out a present. (Author)

  7. Stability tables for opencast mining of coal and sedimentary deposits in inclined seams. Abacos de estabilidad para mineria de carbon y sedimentaria a cielo abierto con capas inclinadas

    Energy Technology Data Exchange (ETDEWEB)

    Ayala, F.J.; Granda, J.R.; Sarti, A.

    1985-01-01

    The six chapters of the book cover the following aspects of strata control in surface mining: design of opencast coal sites; parameters for the geomechanical design of opencast sites; methods for calculating slope stability; calculating the stability of spoil tips with a fractured cement base; calculation of stripping ratios; and stability tables.

  8. Descripción y análisis de capas superpuestas en El castillo de Lindabridis de Calderón

    Directory of Open Access Journals (Sweden)

    Escudero Baztán, Juan Manuel

    2015-06-01

    Full Text Available This paper describes and analyzes the highlights of a play El castillo de Lindabridis of Calderón de la Barca: topics relating to the date of his writing and his performances in the seventeenth century, the management of chivalric sources, the unitary structure, the use of emblematic material through the medieval bestiaries, musical interludes, and the staging and the repetition of themes and motifs, along with some final considerations about gender. All these factors indicate the particular importance of this comedy of Calderón.Este trabajo describe y analiza los puntos más relevantes de una obra caballeresca calderoniana poco conocida como El castillo de Lindabridis: cuestiones relativas a la fecha de su escritura y sus representaciones en el siglo XVII, al manejo de las fuentes caballerescas, a la estructura unitaria, al uso de la emblemática a través de los bestiarios medievales, a los interludios musicales, a la escenificación y la repetición de temas y motivos, junto a unas consideraciones finales sobre el género. Elementos en su conjunto que indican la particular relevancia de esta comedia de gran espectáculo calderoniana.

  9. Notes on the Spanish gas research on carbon layers; Notas sobre la investigation de gas en capas de carbon en Espana

    Energy Technology Data Exchange (ETDEWEB)

    Diaz de Berricano, I.

    2009-07-01

    Among the unconventional gas resources the CBM/CMM plays an outstanding role. In Spain, there have only been drilled three wells with this purpose and none of them has been conclusive. All that means that the real potential of this energy source in the country is yet unknown. (Author)

  10. Comparison of Systems of OOS, Deviation Management and CAPA%OOS系统、偏差管理系统和CAPA系统比较

    Institute of Scientific and Technical Information of China (English)

    陈军丽; 高海燕; 丁恩峰; 郭娅楠

    2010-01-01

    制药企业为了保证产品质量,必须确保质量管理体系正常运行.但是,由于质量系统组成的庞大和复杂性,每个制药企业的质量保证系统都处于波动变化中.因而,制药企业针对质量系统的关键要素,需要持续地,定期地对质量系统进行维护和纠正.在GMP质量管理学发展过程中,偏差管理系统、OOS系统和CAPA系统是不同历史阶段出现的质量系统维护工具.为了帮助制药企业更好的理解和应用这些工具,作者结合自己的工作经验和相关指南、著作,对这3个系统进行比较和分析,并系统研究各自特点和差异.

  11. Organogénesis y embriogénesis en Curcuma longa a partir de capas delgadas de células, segmentos y bases de hoja

    Directory of Open Access Journals (Sweden)

    Zulma Isabel Monsalve Fonnegra

    2014-12-01

    Full Text Available In spite of its pharmacological, nutritional and industrial properties and its great potential market, Curcuma longa L. has not been commercialized to the extent that would be expected. The difficulty of propagation of the species, which is provided exclusively by vegetative to be a sterile triploid, coupled with the environmental requirements of the crop and its high susceptibility to attack by different pathogens, have been the causes for which has not been given a use according to the properties and potential of the plant. As a strategy for obtaining large numbers of germplasm with optimal phytosanitary characteristics, different techniques have been implemented in vitro culture, including the formation of microrrizomas and micropropagation of plants. However, not yet available efficient methods for somatic embryogenesis and organogenesis induction processes. In this study, we report the effect of different plant growth regulators and their combinations on the leaf segments, leaf bases and thin cells layers (TCL of Curcuma longa L. for the callus and embryos induction. The evaluated tissues showed a differential response, according to its characteristics and the plant growth regulators added. Embryogenic response was particularly obtained in leaf bases and TCL. On the other hand, it was possible to induce cauline and root morphogenesis simultaneously in all evaluated tissue. Regenerated plants from leaf bases were more vigorous than the others tissues.

  12. Representações do corpo feminino na moda plus size no Brasil: um olhar multimodal em capas de revistas na versão online

    OpenAIRE

    Silva, Lucimar Aparecida

    2015-01-01

    A exigência por padrões de beleza em relação ao corpo feminino não é algo novo; ao longo do tempo, isso foi se modificando devido a fatores históricos, culturais, sociais. A ditadura da moda, há tempos, tem influenciado comportamentos, estilos, hábitos de mulheres no mundo todo. A determinação por um tipo de beleza torna-se um problema social que abre espaço para o preconceito e a discriminação àqueles que fogem a esse parâmetro; é o caso do corpo feminino representado na moda plus size em ca...

  13. Mediciones de irradiancia solar y capa de ozono durante el eclipse de Sol de 1994 en el Observatorio Astronómico de Rosario, Argentina

    Science.gov (United States)

    Piacentini, R. D.; Micheletti, M. I.

    We show results of measurements made during the Sun's eclipse of November 3, 1994, in Observatorio Astronómico de Rosario (32o 57' S, 60o 37' W, 25 m a.s.l.). The eclipse begin at 8:41 local hour, reached its maximum with 77% of the surface covered at 9:51 and finished at 11:04. The direct solar irradiance of 300 nm and 313 nm were able to be measured, due to the fact that during the whole period the sky remained completed uncovered (zero percent cloudiness). The measurements were made with the portable ozonometer developed by Tocho and co-workers. They show the characterictic decrease due to the occultation of the source, which is approximately proportional to the surface's diminution. When crossing the earth's atmosphere to arrive to the observation point, these irradiances are affected mainly by the ozone layer, specially the irradiance at lower wavelength, what let it to determine by comparison the thickness of this layer. The total ozone thickness distributed between the troposphere and the stratosphere shows an oscillation, whose amplitude, since the occurence of the maximum of occulation, has a mean value of 4%, and whose period is of approximately 2100 seconds, being both numbers considerably larger than the ones registred by Mims III y Mims (Geophysical Research Letters, 20, 367, 1993) during the eclipse of July 11, 1991 and by Tocho, Da Silva y Rivas (XVIII Quadriennial Ozone Symposiom, Italy, September, 1996) during the same eclipse analyzed in the present work, but observed in Salta. As complementary results, we measured the global irradiance and the ambient temperature during this astronomical event.

  14. The wire array Z-pinch: an efficient x-ray source for ICF and a new ion heating mechanism

    Science.gov (United States)

    Haines, M. G.

    2008-10-01

    The Z-pinch provides an efficient x-ray source for driving a hohlraum for inertial confinement fusion. The basic physics of wire-array implosions is reviewed. It can be understood in several sequential stages. Firstly, the wires heat and form a surrounding vapour which ionizes, causing the current to transfer to this lower resistance. The J×B global force leads to ejection of this plasma towards the axis to form a precursor plasma. The wire cores continue to ablate due to the heat flux from the Joule-heated nearby plasma. The cooling of this plasma by the wire-cores leads to a low magnetic Reynolds number so that the precursor plasma carries little or no current. When gaps appear in the liquid/vapour cores the plasma temperature and Reynolds number rise and this plasma accelerates in towards the axis carrying the current. This is the main implosion, and it sweeps up earlier ablated plasma, which acts to reduce Rayleigh-Taylor growth. At stagnation, the ion kinetic energy is thermalized and equipartition heats the electrons, which then radiate in a 5 ns pulse. In some conditions the energy radiated by soft x-rays exceeds the ion kinetic energy by a factor of 3 or 4. A theory has been developed to explain this in which fine-scale, fast growing m= 0 MHD instabilities grow to saturation, viscous dissipation of which leads to ion heating, followed by equipartition. World record ion temperatures of 2-3 billion Kelvin were predicted, and measured at Sandia National Laboratory. Lastly, progress in capsule implosions and in application to inertial fusion energy is reported.

  15. The Wire Array Z-Pinch AN Efficient X-Ray Source for Icf and a New Ion Heating Mechanism

    Science.gov (United States)

    Haines, M. G.

    2009-07-01

    The Z-pinch provides an efficient x-ray source for driving a hohlraum for inertial confinement fusion. The basic physics of wire-array implosions is reviewed. It can be understood in several sequential stages. First, the wires heat and form a surrounding vapor which ionizes, causing the current to transfer to this lower resistance. The J×B global force leads to ejection of this plasma towards the axis to form a precursor plasma. The wire cores continue to ablate due to the heat flux from the Joule-heated nearby plasma. The cooling of this plasma by the wire-cores leads to a low magnetic Reynolds number so that the precursor plasma carries little or no current. When gaps appear in the liquid/vapor cores the plasma temperature and Reynolds' number rise and this plasma accelerates in towards the axis carrying the current. This is the main implosion, and it sweeps up earlier ablated plasma, which acts to reduce Rayleigh-Taylor growth. At stagnation the ion kinetic energy is thermalised and equipartition heats the electrons, which then radiate in a 5 ns pulse. In some conditions the energy radiated as soft x-rays exceeds the ion kinetic energy by a factor of 3 or 4. A theory has been developed to explain this in which fine-scale, fast growing m = 0 MHD instabilities grow to saturation, viscous dissipation of which leads to ion heating, followed by equipartition. World record ion temperatures of 2 to 3 billion Kelvin were predicted, and measured at Sandia National Laboratory. Lastly progress in capsule implosions and in application to inertial fusion energy is reported.

  16. Soft X-Ray Spectroscopic Measurements of Plasma Conditions at Early Times in ICF Experiments on OMEGA. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Griem, Hans R.; Elton, Raymond C.

    2000-02-28

    Our previously-reported observation of a disruptive prepulse on OMEGA, possibly as large as 1% of the extreme ultraviolet (euv) radiation measured from the main pulse, has recently been substantiated by the measurement of euv absorption spectra, prior to the main pulse. The absorption features have been identified with n=2 photoionization in aluminum atoms and ions up to Al5+. Cold aluminum is originally present as a 0.0125-um thick sealant coating applied to a neon-filled (10 atm) CH microballoon, with an euv transmission at the L-absorption edge of {approx}50%. The aluminum in turn is overcoated with 2 um of Mg. The spectra which show the absorption also include continua as well as line emissions from Mg9+ to Mg11+ ions. These occur prior to the onset of laser target irradiation by at least 10 ns, and imply a prepulse irradiance of about 10{sup 12} W/cm{sup 2}. Since the neon and CH are opaque to euv radiation from the rear, a likely scenario is early (prepulse) vaporization of the outer Mg layer, perhaps in hot spots, followed by laser radiation transmitted through the thin Al layer, thereby heating the CH surface. This could provide an euv continuum backlighter for the aluminum that leads to the euv absorption features in various ionic species, perhaps from different points on the target surface.

  17. X-ray self-emission imaging used to diagnose 3-D nonuniformities in direct-drive ICF implosions

    Science.gov (United States)

    Davis, A. K.; Michel, D. T.; Craxton, R. S.; Epstein, R.; Hohenberger, M.; Mo, T.; Froula, D. H.

    2016-11-01

    As hydrodynamics codes develop to increase understanding of three-dimensional (3-D) effects in inertial confinement fusion implosions, diagnostics must adapt to evaluate their predictive accuracy. A 3-D radiation postprocessor was developed to investigate the use of soft x-ray self-emission images of an imploding target to measure the size of nonuniformities on the target surface. Synthetic self-emission images calculated from 3-D simulations showed a narrow ring of emission outside the ablation surface of the target. Nonuniformities growing in directions perpendicular to the diagnostic axis were measured through angular variations in the radius of the steepest intensity gradient on the inside of the ring and through changes in the peak x-ray intensity in the ring as a function of angle. The technique was applied to an implosion to measure large 3-D nonuniformities resulting from two dropped laser beam quads at the National Ignition Facility.

  18. The application of proton spectrometers at the SG-III facility for ICF implosion areal density diagnostics

    Institute of Scientific and Technical Information of China (English)

    Xing Zhang; Jianhua Zheng; Ji Yan; Zhenghua Yang; Ming Su; Yudong Pu; Pin Yang; Xufei Xie; Li Chen; Ming Chen; Tianxuan Huang; Shao’en Jiang; Shenye Liu; Jiamin Yang

    2015-01-01

    Charged particle diagnostics is one of the required techniques for implosion areal density diagnostics at the SG-III facility.Several proton spectrometers are under development, and some preliminary areal density diagnostics have been carried out. The response of the key detector, CR39, to charged particles was investigated in detail. A new track profile simulation code based on a semi-empirical model was developed. The energy response of the CR39 detector was calibrated with the accelerator protons and alphas from a241 Am source. A proton spectrometer based on the filtered CR39 detector was developed, and D–D primary proton measurements were implemented. A step range filter spectrometer was developed,and preliminary areal density diagnostics was carried out. A wedged range filter spectrometer array made of Si with a higher resolution was designed and developed at the SG-III facility. A particle response simulation code by the Monte Carlo method and a spectra unfolding code were developed. The capability was evaluated in detail by simulations.

  19. Innovative high pressure gas MEM's based neutron detector for ICF and active SNM detection.

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Shawn Bryan; Derzon, Mark Steven; Renzi, Ronald F.; Chandler, Gordon Andrew

    2007-12-01

    An innovative helium3 high pressure gas detection system, made possible by utilizing Sandia's expertise in Micro-electrical Mechanical fluidic systems, is proposed which appears to have many beneficial performance characteristics with regards to making these neutron measurements in the high bremsstrahlung and electrical noise environments found in High Energy Density Physics experiments and especially on the very high noise environment generated on the fast pulsed power experiments performed here at Sandia. This same system may dramatically improve active WMD and contraband detection as well when employed with ultrafast (10-50 ns) pulsed neutron sources.

  20. Applying the WHO ICF Framework to Communication Assessment and Goal Setting in Huntington's Disease: A Case Discussion

    Science.gov (United States)

    Power, Emma; Anderson, Alison; Togher, Leanne

    2011-01-01

    Purpose: Huntington's Disease (HD) is a fatal, hereditary neurodegenerative disorder that is characterized by a triad of motor, cognitive and psychiatric symptoms that impact on both communicative effectiveness and the treatment techniques used to maximize communicative participation. The purpose of this article is to describe the application of…