WorldWideScience

Sample records for cap alpha emitters

  1. Alpha particle emitters in medicine

    International Nuclear Information System (INIS)

    Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical applications of alpha emitters. In recent years, however, the potential use of antibodies labeled with alpha emitting radionuclides against cancer has seemed promising because alpha particles are highly effective in cell killing. High dose rates at high LET, effectiveness under hypoxic conditions, and minimal expectancy of repair are additional advantages of alpha emitters over antibodies labeled with beta emitting radionuclides for cancer therapy. Cyclotron-produced astatine-211 (211At) and natural bismuth-212 (212Bi) have been proposed and are under extensive study in the United States and Europe. Radium-223 (223Ra) also has favorable properties as a potential alpha emitting label, including a short-lived daughter chain with four alpha emissions. The radiation dosimetry of internal alpha emitters is complex due to nonuniformly distributed sources, short particle tracks, and high relative specific ionization. The variations in dose at the cellular level may be extreme. Alpha-particle radiation dosimetry, therefore, must involve analysis of statistical energy deposition probabilities for cellular level targets. It must also account fully for nonuniform distributions of sources in tissues, source-target geometries, and particle-track physics. 18 refs., 4 figs

  2. Alpha-emitters for medical therapy workshop

    Energy Technology Data Exchange (ETDEWEB)

    Feinendegen, L.E.; McClure, J.J.

    1996-12-31

    A workshop on ``Alpha-Emitters for Medical Therapy`` was held May 30-31, 1996 in Denver Colorado to identify research goals and potential clinical needs for applying alpha-particle emitters and to provide DOE with sufficient information for future planning. The workshop was attended by 36 participants representing radiooncology, nuclear medicine, immunotherapy, radiobiology, molecular biology, biochemistry, radiopharmaceutical chemistry, dosimetry, and physics. This report provides a summary of the key points and recommendations arrived at during the conference.

  3. Alpha-emitters for medical therapy workshop

    International Nuclear Information System (INIS)

    A workshop on ''Alpha-Emitters for Medical Therapy'' was held May 30-31, 1996 in Denver Colorado to identify research goals and potential clinical needs for applying alpha-particle emitters and to provide DOE with sufficient information for future planning. The workshop was attended by 36 participants representing radiooncology, nuclear medicine, immunotherapy, radiobiology, molecular biology, biochemistry, radiopharmaceutical chemistry, dosimetry, and physics. This report provides a summary of the key points and recommendations arrived at during the conference

  4. Measurement of alpha emitters in radioactive waste

    International Nuclear Information System (INIS)

    The alpha emitters measurement in radioactive waste (10-2Ci/T) is essential for a good fissil materials management. This paper describes 3 classes of devices: device using a neutronic passive counting, device using a neutronic activation and detection of fission gamma, device using a neutronic activation and detection of prompt neutrons fission

  5. Modelling high redshift Lyman-alpha Emitters

    CERN Document Server

    Garel, Thibault; Guiderdoni, Bruno; Schaerer, Daniel; Verhamme, Anne; Hayes, Matthew

    2012-01-01

    We present a new model for high redshift Lyman-Alpha Emitters (LAEs) in the cosmological context which takes into account the resonant scattering of Ly-a photons through expanding gas. The GALICS semi-analytic model provides us with the physical properties of a large sample of high redshift galaxies. We implement a gas outflow model for each galaxy based on simple scaling arguments. The coupling with a library of numerical experiments of Ly-a transfer through expanding or static dusty shells of gas allows us to derive the Ly-a escape fractions and profiles. The predicted distribution of Ly-a photons escape fraction shows that galaxies with a low star formation rate have a f_esc of the order of unity, suggesting that, for those objects, Ly-a may be used to trace the star formation rate assuming a given conversion law. In galaxies forming stars intensely, the escape fraction spans the whole range from 0 to 1. The model is able to get a good match to the UV and Ly-a luminosity function (LF) data at 3 < z <...

  6. Alpha-emitters in the workplace

    International Nuclear Information System (INIS)

    A number of groups of workers have been exposed to α;-particle-emitting radionuclides, of particular importance being the radium dial painters, underground hard rock miners exposed to radon and its decay products, and, more recently, plutonium workers. These occupationally exposed groups are of interest because they allow the direct study of the health effects of exposure to alpha-emitters and the comparison with the level of such effects present among groups exposed predominantly to external sources of low-LET radiation. Hence, these worker groups are important in testing the assumptions that underlie radiological protection. The radium dial painters experienced a pronounced excess of bone cancers and cancers of the paranasal sinuses and mastoid air cells, while a clear radon-related excess of lung cancer is present among the underground hard rock miners. There is little evidence for a radiation-related excess risk of other cancers being present in these groups. A number of groups of workers have been exposed to plutonium in the weapons and civil nuclear industries. The group of plutonium workers at the Mayak nuclear facility in Russia is especially important because of the large numbers exposed to high levels. The Mayak workers have pronounced plutonium-related excess risks of lung, liver and bone cancers, and possibly of other solid tumours, but not leukaemia. Where organ-specific internal doses have been derived, which is presently confined to the lung, risk coefficients are compatible with predictions based on standard models. However, further investigations of the Mayak workforce are required before reliable risk estimates for plutonium exposure may be derived, but this group of workers has the potential of generating definitive risk coefficients for health effects arising from exposure to plutonium. (orig.)

  7. Imaging of alpha emitters in a field environment

    International Nuclear Information System (INIS)

    Cameras sensitive to ultraviolet light can be applied to detection of surface contamination induced by alpha particle emitters. When absorbed in air, alpha particles excite nitrogen molecules and the radiative relaxation creates a faint light emission. This radioluminescence can be used for detection purposes, provided that background lighting levels are low. In this work, three low-light sensitive camera technologies (CCD, EMCCD and ICCD) were utilized in a nuclear facility, and their performance in detecting alpha emitters was investigated. The results show that low readout noise is essential for the detection of radioluminescence, as it allows short exposure times to be used. The ICCD camera was found to perform slightly better than the EMCCD camera in the field, while both enable the detection of MBq level alpha activities in 100 s in the test configuration (camera-target distance 0.5 m). Overall, the cameras and techniques used in this study are shown to be effective in detecting alpha emitters in a standard glovebox. This technology can be applied to nuclear security, safety and safeguards, when stand-off detection of alpha emitters is required

  8. MFTF-. cap alpha. + T progress report

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, W.D. (ed.)

    1985-04-01

    Early in FY 1983, several upgrades of the Mirror Fusion Test Facility (MFTF-B) at Lawrence Livermore National Laboratory (LLNL) were proposed to the fusion community. The one most favorably received was designated MFTF-..cap alpha..+T. The engineering design of this device, guided by LLNL, has been a principal activity of the Fusion Engineering Design Center during FY 1983. This interim progress report represents a snapshot of the device design, which was begun in FY 1983 and will continue for several years. The report is organized as a complete design description. Because it is an interim report, some parts are incomplete; they will be supplied as the design study proceeds. As described in this report, MFTF-..cap alpha..+T uses existing facilities, many MFTF-B components, and a number of innovations to improve on the physics parameters of MFTF-B. It burns deuterium-tritium and has a central-cell Q of 2, a wall loading GAMMA/sub n/ of 2 MW/m/sup 2/ (with a central-cell insert module), and an availability of 10%. The machine is fully shielded, allows hands-on maintenance of components outside the vacuum vessel 24 h after shutdown, and has provisions for repair of all operating components.

  9. Quantum Estimates of Alpha Emitter Life Time

    Directory of Open Access Journals (Sweden)

    B. Santoso

    2006-01-01

    Full Text Available Quantum estimates of several alpha radioactive life time have been made using the probability of quantum tunneling through the nuclear potential barrier. It is assumed that for a given nucleus with mass number A and isotopic number Z, there exists an alpha particle moving freely back and forth in the nucleus with mass and isotopic numbers A -4 and Z-2. If the probability of penetrating the nuclear potential barrier is Τ, then after N times (N=1/Τ hitting the barrier an alpha particle is emitted. To obtain the elapsed time for emitting an alpha particle requires N times τ0, where τ0 is the time travel for alpha across the nuclear diameter, which is dependent on alpha energy. It is assumed here that this kinetic energy is the same as the emitted energy. The emitting alpha kinetic energies here are calculated by the difference of the masses of the parent and daughter nuclei and the alpha particles. They are in closed agreement with the experimental observations. While the alpha radioactive life time are not the same order of magnitudes but give the same linearity on the logarithmic scale as function of the inverse square root of energy.

  10. Alpha emitters in Chernobyl hot particles

    International Nuclear Information System (INIS)

    The alpha radioactive component of hot particles from the Chernobyl fallout was analysed for cases studied previously by gamma spectroscopy. Correlations established from the absolute alpha activity determination and high resolution analysis provided information on actinides release during accident and on some aspects of the Chernobyl reactor fuel composition. Unexpected features revealed during the analysis of one specific particle are presented. 11 refs., 5 figs., 5 tabs. (author)

  11. Alpha emitters in Chernobyl hot particles

    Energy Technology Data Exchange (ETDEWEB)

    Broda, R.; Kubica, B.; Szeglowski, Z.; Zuber, K. (Institute of Nuclear Physics, Krakow (Poland))

    1989-01-01

    The alpha radioactive component of hot particles from the Chernobyl fallout was analyzed for cases studied previously by gamma spectroscopy. Correlations established from the absolute alpha activity determination and high resolution analysis provided information on the release of actinides during the accident and on some aspects of the Chernobyl reactor fuel composition. Unexpected features revealed during the analysis of one specific particle are presented. (orig.).

  12. Effects of internally deposited alpha emitters

    International Nuclear Information System (INIS)

    This study seeks to identify and quantify the human health effects of occupational exposures to radium, use the health effects data from the radium study to predict responses to other alpha-emitting and/or bone-seeking radionuclides at occupational exposure levels and above, and predict the effects of these radionuclides, specifically environmental radium and its daughters, at nonoccupational exposure levels. 14 refs

  13. cap alpha. -skeletal and. cap alpha. -cardiac actin genes are coexpressed in adult human skeletal muscle and heart

    Energy Technology Data Exchange (ETDEWEB)

    Gunning, P.; Ponte, P.; Blau, H.; Kedes, L.

    1983-11-01

    The authors determined the actin isotypes encoded by 30 actin cDNA clones previously isolated from an adult human muscle cDNA library. Using 3' untranslated region probes, derived from ..cap alpha.. skeletal, ..beta..- and ..gamma..-actin cDNAs and from an ..cap alpha..-cardiac actin genomic clone, they showed that 28 of the cDNAs correspond to ..cap alpha..-skeletal actin transcripts. Unexpectedly, however, the remaining two cDNA clones proved to derive from ..cap alpha..-cardiac actin mRNA. Sequence analysis confirmed that the two skeletal muscle ..cap alpha..-cardiac actin cDNAs are derived from transcripts of the cloned ..cap alpha..-cardiac actin gene. Comparison of total actin mRNA levels in adult skeletal muscle and adult heart revealed that the steady-state levels in skeletal muscle are about twofold greater, per microgram of total cellular RNA, than those in heart. Thus, in skeletal muscle and in heart, both of the sarcomeric actin mRNA isotypes are quite abundant transcripts. They conclude that ..cap alpha..-skeletal and ..cap alpha..-cardiac actin genes are coexpressed as an actin pair in human adult striated muscles. Since the smooth-muscle actins (aortic and stomach) and the cytoplasmic actins (..beta.. and ..gamma..) are known to be coexpressed in smooth muscle and nonmuscle cells, respectively, they postulate that coexpression of actin pairs may be a common feature of mammalian actin gene expression in all tissues.

  14. Risk estimates for exposure to alpha emitters

    International Nuclear Information System (INIS)

    The primary scope of this report is to evaluate the risk of lung cancer from occupational exposure to short-lived daughters of radon and thoron. The Subcommittee on Risk Estimates considers that inhalation of radon and thoron daughters is the major radiation hazard from alpha radiation in uranium mining. The secondary scope of this report is the consideration of the applicability of the risk estimates derived from miners to the general public. The risk to members of the public from radium-226 in drinking water is also considered. Some research requirments are suggested

  15. Gaseous alpha emitter diffusion studies using alpha track method

    International Nuclear Information System (INIS)

    Using a very accurate and sensitive analysis method such as alpha track method, the SSNTD group was able to undertake studies on the atomic and molecular processes taking place at low speed and/or very low concentrations, such as diffusion of gaseous alpha radionuclides in gaseous media. For practical application reasons, we began to study the diffusion in air for gaseous alpha radionuclides and aerosols carrying solid alpha radionuclides. The used alpha radionuclides were: Rn-222, as gaseous radionuclide and its solid descendants genetically related, attached to different particles from air, as radioactive aerosols. The source was included into an air tight device with a very well known volume. After 40 days, the radioactive equilibrium was established for all descendants, so that in the device there were the Rn-222 and its descendants, each of them having the same activity. The relative amount/activity ratio of each decay product, at any duration, for any initial mass of Ra-226 parent radionuclide, were calculated using the code UURASE, based on the Bateman general equations, for computing the U-238 radioactive series gamma accumulation. This was adapted for alpha accumulation as ALFAURASE programme. The device which contains the Ra-226 source can be coupled to the calibration system or to the diffusion system, without destroying the radioactive equilibrium. At this coupling, only the radioactive concentration is changed due to the variation of the volume. First of all the device was used for calibrating the CR-39 track detectors for both Rn-222 gaseous radionuclide and aerosol concentration measurements using, in the coupled calibration system, a special 'detector-container' equipped/or not with a filter used for radioactive aerosol stopping. The track detectors CR-39 were etched in NaOH 30%, for 7 hours at 70 deg. C and their studies were performed by optical microscopy using a stereo-microscope Wild M7S and a binocular Zeiss Jena microscope. (authors)

  16. Measurement of Alpha Emitters Concentration in Imported Cigarettes

    International Nuclear Information System (INIS)

    The aime of this study was to measured the alpha emitters concentration of (15) different kinds of imported cigarettes. the nuclear reaction used U-235(n, f) obtained by the bombardment of U-235 with thermal neutrons from (AmBe)neutron source with thermal flux of(5*103 n.cm-2.s-1). The Results obtained showed the values of the Uranium concentration, and varies from (0.041 ppm) in five stares kind to (2.374ppm) in Machbeth (chocolate) 100's kind. All the result obtained are within the limit levels as given by UNSCAR data

  17. Incineration of technological waste contaminated with alpha emitters

    International Nuclear Information System (INIS)

    The French Atomic Energy Commission (CEA), has for several years been engaged in a major program of research and development concerned with the incineration of technological waste contaminated with alpha-emitters. The technical objectives set for this program were: a sizeable reduction in the volume of the waste, ash of a quality suitable for plutonium recovery, built-in flexibility in the operation of the facility, minimum output of secondary waste, nuclear and chemical emissions conforming to accepted standards, and a process entirely consistent with safe practice (with special reference to containment and criticality). This paper discusses how the program was conducted and developed in the laboratory and on a pilot plant

  18. Preconcentration techniques of alpha and beta emitters in environmental samples

    International Nuclear Information System (INIS)

    As is well known it is often necessary to determine very low activities of alpha and beta emitters in environmental and industrial samples for radiation protection purposes. Therefore, due to self absorption problems, the radioisotopes to be determined must be concentrated and isolated before any counting procedure. The radiochemical separation techniques shortly described are the following: the distillation of HTO for the determination of tritium in aqueous solution by liquid scintillation counting; the coprecipitation of Ra-226 and Y-90 before the low background alpha and beta counting. A particular emphasis is devoted to Column Reversed Phase Partition Chromatography (Extraction Chromatography) which has been successfully used in the last years for radioecological and radio-toxicological purposes

  19. Preliminary studies for the determination of alpha emitters using the gross alpha coprecipitation methods

    International Nuclear Information System (INIS)

    The radiological quality of drinking water in Spain is regulated by Nuclear Security Guideline No, 7.7 (Rev.1) of the Nuclear Security Council (NSC). this guideline establishes the protocol to follow when the radiological level exceeds 0,1 Bq.l''1. When this level is passed, the responsible alpha emitter must be identified; ''210 Po, ''226Ra, ''230Th, ''239Pu, ''224Ra, ''234 U and ''138 U. Activity due to these isotopes is usually determined using alpha spectrometry with semiconductor detectors. This method allows the activity of the alpha emitters to be determined with a good sensitivity. however, it requires long radiochemical isolations and long counting times, so the method is not suitable for rough estimate radiological analysis. In this preliminary work, we present the conditioning of the sample-precipitate that is essential for further radiochemical isolations. (Author) 9 refs

  20. Instrument for measuring total alpha particle energies of alpha emitters in ambient air

    Energy Technology Data Exchange (ETDEWEB)

    Kronenberg, S.; Brucker, G.J.; Cummings, B.; Bechtel, E.; Gentner, F.; Horne, S

    2000-11-11

    This paper describes the design, fabrication, testing and evaluation of a self-reading, carbon fiber, electrometer-type instrument. It is used for measuring the total energy of alpha particles emitted in air by progenies of {sup 222}Rn ({sup 218}Po, {sup 214}Pb, and {sup 214}Bi), and sometimes by other types of alpha emitters (e.g. {sup 212}Pb, {sup 238}U, and {sup 239}Pu). The purpose of these measurements is to assess the energy delivered by alpha emission from these sources to the lung tissue. A sample (charged progenies attached to aerosols) is collected on filter paper from a known volume of air and placed on the instrument. The discharge rate indicates the alpha energy in MeV l{sup -1} of air per min that is produced by the alpha emitters. The calibration procedure shows that the instrument has an energy sensitivity for alpha particles of 800.5 MeV/scale unit. The range of the readout scale is 30 units. Measurements of alpha contamination in air were made using this instrument in buildings, private homes and in a standard chamber. The value of the radon concentration in this chamber is traceable back to the US Environmental Protection Agency (EPA) and to the National Institute of Standards and Technology (NIST)

  1. Alpha spectrometry of thick sources. I. Application to alpha emitters determination

    International Nuclear Information System (INIS)

    A method for determining alpha emitters by silicon surface barrier detector spectroscopy using thick sources is studied. Two types of spectra have been obtained. They have different shapes of line according to the procedure used for preparing the sources. For both spectra a computing least square programme has been developed. In this way it is possible to calculate line intensities with accuracy better than 20 percent. (author)

  2. Determination of substraces of alpha emitter elements in water

    International Nuclear Information System (INIS)

    To determine alpha emitter elements in water by alpha spectrometry, it is necessary to use large volumes of samples, concentration techniq-ues and to separate the elements of interest. In this report a study is presented about two concentration techniques and the process of analysis. Firstly, the stages of concentration method by iron hydroxide coprecipitation were studied in order to improve the results. The combination of liquid-liquid extraction and ion exchange techniques was the best way. Secondly, the technique by adsorption on manganese dioxide was studied. To apply this technique it was necessary to develop analysis methods to separate uranium, thorium, plutonium, americium and radium. These methods were designed combining several techniques of separation: liquid-liquid extraction, liquid-solid extraction, ionic exchange and coprecipitation. After the analysis methods were developped the adsorption on manganese dioxide with artificial samples was studied in the laboratory. Finally, the method of adsorption on manganese dioxide was studied to determine uranium, thorium and radium in the drinking water of Madrid. (Author)

  3. Alpha decay and nuclear deformation: the case for favoured alpha transitions of even-even emitters

    International Nuclear Information System (INIS)

    Alpha decay half-life for ground-state to ground-state transitions of 174 even-even alpha emitters has been calculated from a simple, Gamow-like model in which the quadrupole deformation of the product nucleus (assumed to have an ellipsoidal shape) is taken into account. The assumption made is that before tunnelling through a purely Coulomb potential barrier the two-body system oscillates isotropically, thus giving rise to an equivalent, average polar direction θ0 (referred to the symmetry axis of the ellipsoid) for alpha emission. It is shown that the experimental half-life data are much better reproduced by the present description than in the spherical shaped approximation for the daughter nucleus. (author)

  4. Alpha-human atrial natriuretic polypeptide (. cap alpha. -hANP) specific binding sites in bovine adrenal gland

    Energy Technology Data Exchange (ETDEWEB)

    Higuchi, K.; Nawata, H.; Kato, K.I.; Ibayashi, H.; Matsuo, H.

    1986-06-13

    The effects of synthetic ..cap alpha..-human atrial natriuretic polypeptide (..cap alpha..-hANP) on steroidogenesis in bovine adrenocortical cells in primary monolayer culture were investigated. ..cap alpha..-hANP did not inhibit basal aldosterone secretion. ..cap alpha..-hANP induced a significant dose-dependent inhibition of basal levels of cortisol and dehydroepiandrosterone (DHEA) secretion and also of aCTH (10/sup -8/M)-stimulated increases in aldosterone, cortisol and DHEA secretion. Visualization of (/sup 125/I) ..cap alpha..-hANP binding sites in bovine adrenal gland by an in vitro autoradiographic technique demonstrated that these sites were highly localized in the adrenal cortex, especially the zona glomerulosa. These results suggest that the adrenal cortex may be a target organ for direct receptor-mediated actions of ..cap alpha..-hANP.

  5. Optimization of operating parameters for low level measurements of alpha emitters by alpha spectrometry

    International Nuclear Information System (INIS)

    The members of public are exposed to both natural and anthropogenic sources of radiation. Naturally occurring radioactive materials comprises of uranium, thorium and their decay products with other radionuclides such as 40K, 3H, 22Na, 7Be, etc. Anthropogenic radionuclides comprises of 137Cs, 90Sr, 239Pu, 241Am, etc. They emit alpha, beta and gamma radiations. Measurement at low level radioactivity is challenging due to interference and other inherent uncertainties. Alpha emitters comprises of 238U and 232Th with their daughters along with those of anthropogenic origin like 239Pu, 241Am, etc. Measurement of alpha emitters is essential by considering the adverse effects of alpha radiation while inside the body. Alpha spectrometry is a sensitive and direct technique to identify and quantify the alpha emitters having detection limit, two to three order of magnitude lower than gamma spectrometry. Standardization of operating parameters is imperative prior to analysis. An attempt has been made to optimize the parameters for an Eight Chamber Alpha Spectrometer (ORTEC) with 450 mm2PIPS detector surface area, with an operating voltage of 50 volt and current of 20-30 nano amperes. Energy calibration of each chamber was done with Pu-Am mixed source and natural uranium standard source. Efficiency of each detector measured with various sources to detector distance for the standard sources was nearly same at equivalent distances, e.g. it is coming around 16% at 8 mm source to detector distance (Rack 2) of each chamber. At 4 mm source to detector distance (Rack-1) it is 25% and gradually it decreases upto 2% at 40 mm source to detector distance (Rack-10). Resolution of 241Am peak was found to 20-25 keV at 8 mm source to detector distance and varies with distance from the detector. It was found that 50% decrease in resolution i.e. FWHM value with the increase in source to detector distance. In the energy range of 4-10 MeV, 8 counts is obtained as background count per 86,000 secs

  6. A device for the remote detection of alpha emitters under field conditions

    NARCIS (Netherlands)

    Simakov, AB

    2005-01-01

    The portable DOP device was designed for the ecological monitoring of the radiation of alpha radioactive nuclides, such as plutonium, uranium, radium, etc. Under field conditions, it can detect alpha emitters at distances of up to 0.5 m. The device's performance data are as follows: the lower thresh

  7. Method validation to determine total alpha beta emitters in water samples using LSC

    International Nuclear Information System (INIS)

    In this work a method was validated to determine gross alpha and beta emitters in water samples using liquid scintillation counter. 200 ml of water from each sample were evaporated to 20 ml and 8 ml of them were mixed with 12 ml of the suitable cocktail to be measured by liquid scintillation counter Wallac Winspectral 1414. The lower detection limit by this method (LDL) was 0.33 DPM for total alpha emitters and 1.3 DPM for total beta emitters. and the reproducibility limit was (± 2.32 DPM) and (±1.41 DPM) for total alpha and beta emitters respectively, and the repeatability limit was (±2.19 DPM) and (±1.11 DPM) for total alpha and beta emitters respectively. The method is easy and fast because of the simple preparation steps and the large number of samples that can be measured at the same time. In addition, many real samples and standard samples were analyzed by the method and showed accurate results so it was concluded that the method can be used with various water samples. (author)

  8. Study of /sup 3/H+. cap alpha. and /sup 3/He+. cap alpha. elastic scattering in a state with zero orbital angular momentum

    Energy Technology Data Exchange (ETDEWEB)

    Chopovskii, L. L.

    1988-12-01

    An asymptotic wave function of the relative motion of clusters at zero interaction energy is derived in the oscillator representation. The set of equations of the algebraic version of the resonating-group method (RGM) is transformed to the zero-energy limit of the relative cluster motion. The /sup 3/H+..cap alpha.. and /sup 3/He+..cap alpha.. scattering lengths are calculated in the single-channel RGM variant on the basis of the derived equations. The possibility of experimentally observing large scattering lengths for light charged clusters is predicted, viz., /similar to/10--23 F in the /sup 3/H+..cap alpha.. channel and /similar to/30--82 F in the /sup 3/He+..cap alpha.. channel.

  9. Optical imaging of alpha emitters: simulations, phantom, and in vivo results

    Science.gov (United States)

    Boschi, Federico; Meo, Sergio Lo; Rossi, Pier Luca; Calandrino, Riccardo; Sbarbati, Andrea; Spinelli, Antonello E.

    2011-12-01

    There has been growing interest in investigating both the in vitro and in vivo detection of optical photons from a plethora of beta emitters using optical techniques. In this paper we have investigated an alpha particle induced fluorescence signal by using a commercial CCD-based small animal optical imaging system. The light emission of a 241Am source was simulated using GEANT4 and tested in different experimental conditions including the imaging of in vivo tissue. We believe that the results presented in this work can be useful to describe a possible mechanism for the in vivo detection of alpha emitters used for therapeutic purposes.

  10. Localization of alpha emitters by damage production in a thin film. Application to the study of alpha emitter diffusion in irradiated samples

    International Nuclear Information System (INIS)

    The process of recording α particles on cellulose nitrate films, called alpha-graphy, is applied to the study of the diffusion of α-emitting elements in irradiated alloys. The existence of diffusion is shown by attacking the film with concentrated caustic soda after exposition. The insensitivity of the recorder to β γ radiation emitted by the sample after passing in the reactor makes it possible to operate with long exposure times and to detect small diffusions. The concentration-penetration curves are drawn up after carrying out a densitometric analysis of the alpha-graphies. - As the cellulose nitrate is affected only by α particles of energies of between 0.5 and 4 MeV, it was first necessary to determine the yield of the recorder for α particles emitted by a thick source, i.e. whose energy varies between 0 and E0, E0 being the energy of the alpha emitter. - The concentration C of the α-emitter, as a function of the optical density D of the alpha-graphy, and of the exposure time t is given by a simple relationship: C = D/at where a is an experimental constant determined by calibration. It depends on the nature of the cellulose nitrate, of the α-emitting element and of the alloy studied. (authors)

  11. Clustering of Lyman alpha emitters at z ~ 4.5

    OpenAIRE

    Kovač, Katarina; Somerville, Rachel S.; Rhoads, James E.; Malhotra, Sangeeta; Wang, Junxian

    2007-01-01

    We present the clustering properties of 151 Lyman alpha emitting galaxies at z ~ 4.5 selected from the Large Area Lyman Alpha (LALA) survey. Our catalog covers an area of 36' x 36' observed with five narrowband filters. We assume that the angular correlation function w(theta) is well represented by a power law A_w = Theta^(-beta) with slope beta = 0.8, and we find A_w = 6.73 +/- 1.80. We then calculate the correlation length r_0 of the real-space two-point correlation function xi(r) = (r/r_0)...

  12. Real-time alpha emitter assay of large volumes

    International Nuclear Information System (INIS)

    In this paper we discuss the design and behavior of a High Airflow Monitor (HAFM) based on Long-Range Alpha Detector (LRAD) technology [1]. The low air resistance construction of the HAFM enables the high airflow crucial for assay of rooms, vaults, or cargo vehicles. This is accomplished by orienting plates parallel to the airflow rather than perpendicular, as are the grids in other LRADS. As will be shown in this paper, the advantages of an LRAD-based volume monitor are its inexpensive simplicity, ruggedness, and its ability to detect contamination that is hidden from traditional alpha detection methods such as Geiger-Muller, gas cell, or solid-state detectors

  13. Interactive session: alpha emitters, fashion or reality? radionuclides and molecules availability

    International Nuclear Information System (INIS)

    Full text of publication follows. This introduction to the interactive session will simply be based on statements related to the future of therapy in nuclear medicine with some emphasis on the use of alpha-emitters. Some hypotheses will be developed on topics such as 'How will look nuclear medicine in 2025?', 'Do we have enough information to support the use of alpha in therapy?' 'Does it make sense to develop alpha-labelled molecules without long term financial commitment?', 'Will sufficient amounts of radionuclides available when the drugs will be ready for marketing?', 'Do we know enough about alpha emitters toxicity?', 'Is personalized medicine really the solution of the future of health care?', 'How can we convince authorities about the advantages of alpha labelled molecules?', 'Is the development of alpha RIT more expensive or more difficult than beta RIT?', 'Where are all the beta-emitter under development gone?', 'With alpha-emitters, are we speaking about 2025 or 2050?', 'Will Xofigo be a success?', 'What will be the real role of pharmaceutical companies in radiotherapy?', 'Who are the most afraid about radioactivity, the patients or the authorities?'. The speaker will provide his own opinion about each topic. Will you agree or not with him? What is your opinion? (author)

  14. Membrane transfer of. cap alpha. -tocopherol: influence of soluble. cap alpha. -tocopherol-binding factors from the liver, lung, heart and brain of the rat

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, D.J.; Mavis, R.D.

    1981-10-25

    The pH of liver supernatant was lowered from 7.4 to 5.1, which removed 23% of the soluble protein and 97% of the lipid-soluble phosphate, increased the total ..cap alpha..-tocopherol transfer activity 1.3-fold and the specific activity of the transfer rate 1.6-fold. This transfer activity was proportional to time up to 4 min and to protein concentrations up to 0.1 mg/ml. Fractionation of the pH 5.1-treated liver supernatant by gel filtration produced a single peak of ..cap alpha..-tocopherol transfer activity of M/sub r/ = 34,000 and a single peak of ..cap alpha..-tocopherol-binding activity which was coincident with the transfer activity. The transfer rate of this peak of activity was 316 pmol/min/mg of protein, a 9-fold purification over the original untreated supernatant. This ..cap alpha..-tocopherol transfer rate was reduced by 83 and 96% following pronase digestion or heat treatment (80/sup 0/C) of the soluble fraction, respectively, while trypsin digestion reduced the transfer rate only 18% and phospholipase C digestion had no effect. Untreated liver supernatant possessed the peak of binding activity of M/sub r/ = 34,000 and a high molecular weight binding fraction that eluted at the void volume. Heart and brain supernatants also possessed an ..cap alpha..-tocopherol-binding fraction that eluted at the void volume, while lung supernatant lacked binding activity.

  15. Regulatory sequences within DQ. cap alpha. and DQ. beta

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, K.; Peterlin, B.M.

    1986-03-05

    The Class II Histocompatibility Antigen DQ is characterized by tissue specific expression, relatively late appearance in development and modulation of expression in response to gamma interferon, phorbol 12-myristate 13-acetate (PMA), and prostaglandins of the E series. They have utilized the sensitive reporter function of chloramphenicol acetyl transferase (CAT) in transient expression assays to screen for the presence of regulatory regions within the DQ..cap alpha.. and DQ..beta.. genes. Two regions have been identified which stimulate CAT transcription in transfected cells. One region includes the first intron of DQ..beta.. and the other region brackets the first exon of DQ/sup 2/. These regions are both tissue specific in their stimulation of CAT transcription i.e., both regions stimulate transcription more effectively in a DQ expressing B cell line (BJAB) than in a DQ negative T cell line (Jurkat). Additionally, the CAT plasmids containing the first intron of DQ..beta.. appear to be gamma interferon responsive. Transfection of these plasmids into BJAB followed by treatment of the cells with gamma interferon for 24 hours results in a doubling of the CAT transcription. This increase is analogous to the endogenous DQ response to gamma interferon. These two regions undoubtedly contribute to the complex regulation of DQ expression.

  16. Crystal structure of 2-chloroacetamide (. cap alpha. form): a reinvestigation

    Energy Technology Data Exchange (ETDEWEB)

    Kalyanaraman, B.; Kispert, L.D.; Atwood, J.L.

    1978-01-01

    The crystal structure of the ..cap alpha.. form of 2-chloroacetamide, grown by sublimation, has been determined from three-dimensional counter data and refined by full-matrix least-squares techniques. The crystals belong to the monoclinic space group P2/sub 1//c with a = 10.263(8), b = 5.142(5), c = 7.458(6) A, ..beta.. = 98.72(4)/sup 0/, and D/sub x/ = 1.60 g cm/sup -3/ for Z = 4. The final R factor for 518 observed reflections is 0.037. The molecule exists as a hydrogen-bonded dimer in the crystal structure. The configuration of atoms C(1), C(2), O, and N is planar to within 0.008 A, and the Cl-C(1)-C(2)-O dihedralangle equals 168/sup 0/. The dimeric hydrogen bonding as well as the CH/sub 2/ conformation favors the stabilization of a transient oxygen-centered radical. 3 figures, 3 tables.

  17. SU-E-J-03: A Comprehensive Comparison Between Alpha and Beta Emitters for Cancer Radioimmunotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Huang, C.Y. [University of Sydney, Camperdown, NSW (Australia); Guatelli, S [University of Wollongong, Wollongong, NSW (Australia); Oborn, B [Illawarra Cancer Care Centre, Wollongong, NSW (Australia); Allen, B [University of Western Sydney, Liverpool, NSW (Australia)

    2014-06-01

    Purpose: The purpose of this study is to perform a comprehensive comparison of the therapeutic efficacy and cytotoxicity of alpha and beta emitters for Radioimmunotherapy (RIT). For each stage of cancer development, specific models were built for the separate objectives of RIT to be addressed:a) kill isolated cancer cells in transit in the lymphatic and vascular circulation,b) regress avascular cell clusters,c) regress tumor vasculature and tumors. Methods: Because of the nature of short range, high LET alpha and long energy beta radiation and heterogeneous antigen expression among cancer cells, the microdosimetric approach is essential for the RIT assessment. Geant4 based microdosimetric models are developed for the three different stages of cancer progression: cancer cells, cell clusters and tumors. The energy deposition, specific energy resulted from different source distribution in the three models was calculated separately for 4 alpha emitting radioisotopes ({sup 211}At, {sup 213}Bi, {sup 223}Ra and {sup 225}Ac) and 6 beta emitters ({sup 32}P, {sup 33}P, {sup 67}Cu, {sup 90}Y, {sup 131}I and {sup 177}Lu). The cell survival, therapeutic efficacy and cytotoxicity are determined and compared between alpha and beta emitters. Results: We show that internal targeted alpha radiation has advantages over beta radiation for killing isolated cancer cells, regressing small cell clusters and also solid tumors. Alpha particles have much higher dose specificity and potency than beta particles. They can deposit 3 logs more dose than beta emitters to single cells and solid tumor. Tumor control probability relies on deep penetration of radioisotopes to cancer cell clusters and solid tumors. Conclusion: The results of this study provide a quantitative understanding of the efficacy and cytotoxicity of RIT for each stage of cancer development.

  18. SU-E-J-03: A Comprehensive Comparison Between Alpha and Beta Emitters for Cancer Radioimmunotherapy

    International Nuclear Information System (INIS)

    Purpose: The purpose of this study is to perform a comprehensive comparison of the therapeutic efficacy and cytotoxicity of alpha and beta emitters for Radioimmunotherapy (RIT). For each stage of cancer development, specific models were built for the separate objectives of RIT to be addressed:a) kill isolated cancer cells in transit in the lymphatic and vascular circulation,b) regress avascular cell clusters,c) regress tumor vasculature and tumors. Methods: Because of the nature of short range, high LET alpha and long energy beta radiation and heterogeneous antigen expression among cancer cells, the microdosimetric approach is essential for the RIT assessment. Geant4 based microdosimetric models are developed for the three different stages of cancer progression: cancer cells, cell clusters and tumors. The energy deposition, specific energy resulted from different source distribution in the three models was calculated separately for 4 alpha emitting radioisotopes (211At, 213Bi, 223Ra and 225Ac) and 6 beta emitters (32P, 33P, 67Cu, 90Y, 131I and 177Lu). The cell survival, therapeutic efficacy and cytotoxicity are determined and compared between alpha and beta emitters. Results: We show that internal targeted alpha radiation has advantages over beta radiation for killing isolated cancer cells, regressing small cell clusters and also solid tumors. Alpha particles have much higher dose specificity and potency than beta particles. They can deposit 3 logs more dose than beta emitters to single cells and solid tumor. Tumor control probability relies on deep penetration of radioisotopes to cancer cell clusters and solid tumors. Conclusion: The results of this study provide a quantitative understanding of the efficacy and cytotoxicity of RIT for each stage of cancer development

  19. Can galactic outflows explain the properties of Ly-alpha emitters?

    CERN Document Server

    Orsi, Alvaro; Baugh, Carlton M

    2011-01-01

    We study the properties of Ly-alpha emitters in a cosmological framework by computing the escape of Ly-alpha photons through galactic outflows. We combine the GALFORM semi-analytical model of galaxy formation with a Monte Carlo Ly-alpha radiative transfer code. The properties of Ly-alpha emitters at 0alpha line profiles predicted by the two outflow geometries in terms of their width, asymmetry and shift from the line centre for a set of outflows with different hydrogen column densities, expansion velocities and metallicities. In general, the Ly-alpha line profile of the Shell geometry is broader and more asymmetric, and the Ly-alpha escape fraction is lower than with the Wind geometry for the same set of parameters. In order to implement the outflow geometries in the semi-analytical model GALFORM, a number of free parameters ...

  20. A novel technique for the rapid identification of alpha emitters released during a radiological incident.

    Science.gov (United States)

    Dilbeck, George A; Taylor, Bud; Leitch, Jerrold; Silverstone, Marina; Moore, Brian; Honsa, Patricia

    2006-10-01

    Before the May 2003 TOPOFF II exercise in Seattle, the U.S. EPA's Laboratory in Las Vegas prepared five spiked samples to be analyzed by the Washington State Department of Health's (WSDOH) Radiation Laboratory. Two of these were simulated deposition samples prepared on packaging tape. Laboratories throughout the world are investigating rapid methods for analyzing plume-borne radioactive materials. While measuring gamma emitters in environmental samples is fairly straightforward, the potential presence of alpha emitters adds complexity. The short range of alpha particles and the high degree of energy interference between nuclides usually require chemical separations and very thin mounts for alpha spectrometry. Work published on Frisch-Grid alpha counting of transuranics in soil and the commercial development of radon-rejection for air filters indicate that alpha spectrometry can be used directly on some media with success. This suggests that plume-borne material sampled from air or freshly deposited surface layers may be counted directly by alpha spectrometry, making it possible to identify both alpha and gamma emitters and determine their relative concentrations. The long-range objective is to propose a sampling method that can be used for rapid qualitative and semi-quantitative analyses using conventional radioanalytical instruments, with minimal preparation. This paper describes experimentation with this approach during a real-time exercise. All samples were prepared by spiking with (137)Cs, (241)Am, (238)Pu, and (239)Pu and presented to the WSDOH's Radiation Laboratory for analysis during TOPOFF II. The laboratory quickly identified and determined the ratios of all four contaminants on the tape samples using sequential alpha spectrometry and gamma-ray spectroscopy without chemical separations. PMID:16966874

  1. Increased concentration of. cap alpha. - and. gamma. -endorphin in post mortem hypothalamic tissue of schizophrenic patients

    Energy Technology Data Exchange (ETDEWEB)

    Wiegant, V.M.; Verhoef, C.J.; Burbach, J.P.H.; de Wied, D.

    1988-01-01

    The concentrations of ..cap alpha..-, ..beta..- and ..gamma..-endorphin were determined by radioimmunoassay in HPLC fractionated extracts of post mortem hypothalamic tissue obtained from schizophrenic patients and controls. The hypothalamic concentration of ..cap alpha..- and ..gamma..-endorphin was significantly higher in patients than in controls. No difference was found in the concentration of ..beta..-endorphin, the putative precursor of ..cap alpha..- and ..gamma..-endorphins. These results suggest a deviant metabolism of ..beta..-endorphin in the brain of schizophrenic patients. Whether this phenomenon is related to the psychopathology, or is a consequence of ante mortem farmacotherapy, remains to be established.

  2. Incineration of technological waste contaminated with alpha emitters

    International Nuclear Information System (INIS)

    A large R and D programme is in progress at the CEA on alpha-bearing waste incineration. The program is developed in the laboratory and a pilot plant including the following aspects: physico-chemical characterization of wastes, study of thermal decomposition of wastes, laboratory study of generated gases (first with inactive then with active wastes), development of an industrial pilot plant with inactive wastes, study of corrosion resistance of material (laboratory and pilot plant), study and qualification of nuclear measurements on wastes, ashes and equipment

  3. Alpha emitters activity measurement using the defined solid angle method

    International Nuclear Information System (INIS)

    The defined solid angle counting method can reach a very high accuracy, specially for heavy ions as alpha particles emitted by a radioactive source. The activity measurement of such sources with a relative uncertainty of the order of 0.01% is investigated. Such an accuracy is available only under suitable conditions: the radiation emitted by the source must be isotropic and all the particles emitted in the effective solid angle must be detected. The efficiency detection value must be equal to unity and phenomena such as absorption or scattering must be null. It is shown that corrections often become necessary. All parameters which can influence the measurements are studied

  4. Clustering of Lyman alpha emitters at z ~ 4.5

    CERN Document Server

    Kovaa, Katarina; Rhoads, James E; Malhotra, Sangeeta; Wang, JunXian

    2007-01-01

    We present the clustering properties of 151 Lyman alpha emitting galaxies at z ~ 4.5 selected from the Large Area Lyman Alpha (LALA) survey. Our catalog covers an area of 36' x 36' observed with five narrowband filters. We assume that the angular correlation function w(theta) is well represented by a power law A_w = Theta^(-beta) with slope beta = 0.8, and we find A_w = 6.73 +/- 1.80. We then calculate the correlation length r_0 of the real-space two-point correlation function xi(r) = (r/r_0)^(-1.8) from A_w through the Limber transformation, assuming a flat, Lambda-dominated universe. Neglecting contamination, we find r_0 = 3.20 +/- 0.42 Mpc/h. Taking into account a possible 28% contamination by randomly distributed sources, we find r_0 = 4.61 +/- 0.6 Mpc/h. We compare these results with the expectations for the clustering of dark matter halos at this redshift in a Cold Dark Matter model, and find that the measured clustering strength can be reproduced if these objects reside in halos with a minimum mass of ...

  5. Alpha emitters in nuclear waste. Extension of the procedure for low and medium level activity waste

    International Nuclear Information System (INIS)

    The present paper describes a separative method for the determination of U, Pu, Am, Np, Th and Cm as alpha emitters and 3H, Sr, and Ni as beta emitters, when present in aqueous samples of nuclear waste, by using chromatographic separations, liquid scintillation counting and alpha spectrometry. The main separation is performed in one step by coprecipitation of the alpha emitters with yttrium hydroxide at pH = 9-10 after distillation of tritium until dryness and dissolution of the residue in 2M HCI. Actinides are precipitated while strontium and nickel remain in supernatant. Nickel is separated by precipitation with dimetyglioxime in the supernatant and measured by LSC. Strontium is separated by chromatography after conditioning the supernatant (which also contained nickel) and measured by LSC. The actinides fraction is re dissolved in nitric acid and percolated through three chromatographic columns (TEVA, U-TEVA and TRU-SPEC) conditioning the different fractions for measuring by alpha spectrometry. The spectra of the different fractions are presented together with the detection limits and the recoveries obtained on spiked samples. (author)

  6. Microscopic dose to lung from inhaled alpha emitters in humans

    International Nuclear Information System (INIS)

    Because of the short range of alpha particles in tissue, the degree of uniformity of irradiation of the lung varies greatly depending on the form of the inhaled material. Animal studies have shown that the degree of dose uniformity influences the risk of lung cancer. This study investigates the radiation dose distribution of plutonium in human lung. Numerical maps of tissue configuration and target cell locations are obtained from histological sections of human lung tissue stained to enhance the identification of putative cell types for parenchymal lung cancers, i.e. alveolar type II cells and Clara cells. Monte Carlo simulations are used to obtain dose distribution around individual particles, and these distributions are used to compute dose distribution in volumes of lung tissue. Lung dose is characterised both by the degree of non-uniformity of irradiation and the relative degree of irradiation of all tissue versus the special cells of interest. (authors)

  7. Synthetic. cap alpha. subunit peptide 125-147 of human nicotinic acetylcholine receptor induces antibodies to native receptor

    Energy Technology Data Exchange (ETDEWEB)

    McCormick, D.J.; Griesmann, G.E.; Huang, Z.; Lennon, V.A.

    1986-03-05

    A synthetic peptide corresponding to residues 125-147 of the Torpedo acetylcholine receptor (AChR) ..cap alpha.. subunit proved to be a major antigenic region of the AChR. Rats inoculated with 50 ..mu..g of peptide (T ..cap alpha.. 125-147) developed T cell immunity and antibodies to native AChR and signs of experimental autoimmune myasthenia gravis. They report the synthesis and preliminary testing of a disulfide-looped peptide comprising residues 125-147 of the human AChR ..cap alpha.. subunit. Peptide H ..cap alpha.. 125-147 differs from T ..cap alpha.. 125-147 at residues 139 (Glu for Gln) and 143 (Ser for Thr). In immunoprecipitation assays, antibodies to Torpedo AChR bound /sup 125/I-labelled H..cap alpha.. 125-147 antibody bound H..cap alpha.. 125-147, but monoclonal antibodies to an immunodominant region of native AChR bound neither H..cap alpha.. 125-147 nor T ..cap alpha.. 125-147. Rats immunized with H ..cap alpha.. 125-147 produced anti-mammalian muscle AChR antibodies that induced modulation of AChRs from cultured human myotubes. Thus, region 125-147 of the human AChR ..cap alpha.. subunit is extracellular in muscle, and is both antigenic and immunogenic. It remains to be determined whether or not autoantibodies to this region may in part cause the weakness or myasthenia gravis in man.

  8. Rapid determination of alpha emitters using Actinide resin.

    Science.gov (United States)

    Navarro, N; Rodriguez, L; Alvarez, A; Sancho, C

    2004-01-01

    The European Commission has recently published the recommended radiological protection criteria for the clearance of building and building rubble from the dismantling of nuclear installations. Radionuclide specific clearance levels for actinides are very low (between 0.1 and 1 Bq g(-1)). The prevalence of natural radionuclides in rubble materials makes the verification of these levels by direct alpha counting impossible. The capability of Actinide resin (Eichrom Industries, Inc.) for extracting plutonium and americium from rubble samples has been tested in this work. Besides a strong affinity for actinides in the tri, tetra and hexavalent oxidation states, this extraction chromatographic resin presents an easy recovery of absorbed radionuclides. The retention capability was evaluated on rubble samples spiked with certified radionuclide standards (239Pu and 241Am). Samples were leached with nitric acid, passed through a chromatographic column containing the resin and the elution fraction was measured by LSC. Actinide retention varies from 60% to 80%. Based on these results, a rapid method for the verification of clearance levels for actinides in rubble samples is proposed. PMID:15177360

  9. Radiative Transfer Modeling of Lyman Alpha Emitters. I. Statistics of Spectra and Luminosity

    OpenAIRE

    Zheng, Zheng; Cen, Renyue; Trac, Hy; Miralda-Escude, Jordi

    2009-01-01

    We combine a cosmological reionization simulation with box size of 100Mpc/h on a side and a Monte Carlo Lyman-alpha (Lya) radiative transfer code to model Lyman Alpha Emitters (LAEs) at z~5.7. The model introduces Lya radiative transfer as the single factor for transforming the intrinsic Lya emission properties into the observed ones. Spatial diffusion of Lya photons from radiative transfer results in extended Lya emission and only the central part with high surface brightness can be observed...

  10. Prolixe-prototype reprocessing unit for irradiating wastes contamined with alpha emitters

    International Nuclear Information System (INIS)

    A large number of hot cells are employed for research on nuclear fuel reprocessing and the production of isotope of transuranium elements. These activities generate solid wastes highly contaminated with alpha, beta, gamma emitters. The Prolixe hot cell was built in order to: 1/ reprocess the solid wastes contaminated with alpha, beta, gamma emitters produced in the Radiochemistry building: 2/ produce package wastes storable in shallow-ground disposal sites: 3/ develop a process sufficiently flexible to make it applicable to waste produced in other installations. The process is based on waste leaching after grinding. Depending on the type of wastes the leaching reactant will have a different composition 1/ nitric acid solution for cellulose waste: 2/ nitric solutions containing Ag(II) for other material. The complete process should achieve: 1/ a high waste volume reduction factor: 2/ the production of immobilized waste packages storage in shallow-ground disposal sites: 3/ the recycling of transuranium elements: 4/ the generation of a minimal volume of effluents. This process can be considered as an alternative process to incineration for the reprocessing of solid wastes highly contaminated with alpha, beta, gamma emitters

  11. Studying reionization with the next generation of Ly-alpha emitter surveys

    CERN Document Server

    Jensen, Hannes; Iliev, Ilian; Laursen, Peter; Mellema, Garrelt; Zackrisson, Erik

    2014-01-01

    We study the prospects for constraining the ionized fraction of the intergalactic medium (IGM) at $z>6$ with the next generation of large Ly$\\alpha$ emitter surveys. We make predictions for the upcoming Subaru Hyper Suprime-Cam (HSC) Ly$\\alpha$ survey and a hypothetical spectroscopic survey performed with the James Webb Space Telescope (JWST). Considering various scenarios where the observed evolution of the Ly$\\alpha$ luminosity function of Ly$\\alpha$ emitters at $z>6$ is explained partly by an increasingly neutral IGM and partly by intrinsic galaxy evolution, we show how clustering measurements will be able to distinguish between these scenarios. We find that the HSC survey should be able to detect the additional clustering induced by a neutral IGM if the global IGM neutral fraction is greater than $\\sim$20 per cent at $z=6.5$. If measurements of the Ly$\\alpha$ equivalent widths (EWs) are also available, neutral fractions as small as 10 per cent may be detectable by looking for correlation between the EW an...

  12. Present state and future perspective of radionuclide therapy with alpha emitters

    International Nuclear Information System (INIS)

    Described are the advantage of alpha emitters in cancer treatment, developmental process of therapeutics of bone metastasis with 223Ra and future perspective of radiotherapy with the emitters. Alpha-ray has characteristics of high linear energy transfer (LET) and short range. The average energy of emitted alpha-rays from 223Ra and its daughter nuclides is 27.4 MeV and the range in the tissue, 89Sr are 0.58 MeV and 2.4 mm, respectively. Alpha's LET 80 keV/mc-m is 400 times as high as that of 89Sr beta-ray (0.2 keV/mc-m), indicating the much higher relative biological effectiveness (RBE) of the former. Phase I-III trials concerning the efficacy and safety of 223Ra (chloride) conducted in Western countries have led to the approval of the agent by FDA in 2013 for the therapy of patients with castration-resistant bone metastases of prostate cancer. In Japan, the medical 223Ra is readily usable and investigations for its application to the therapy of the hormone-resistant prostate cancer have been under completion by Japan Society of Nuclear Medicine. The exact mechanism of the 223Ra efficacy on the metastasis is rather obscure but is conceivably related with various interactions between alpha-ray and biological substrates. Future problems of the emitters for internal medical use such as their radiation management, micro-dosimetry and delivery system are now eagerly discussed in the world. (T.T)

  13. Clustering and lifetime of Lyman Alpha Emitters in the Epoch of Reionization

    CERN Document Server

    Hutter, Anne; Müller, Volker

    2015-01-01

    We calculate Lyman Alpha Emitter (LAE) angular correlation functions (ACFs) at $z\\simeq6.6$ and the fraction of lifetime (for the 100 Myrs preceding $z\\simeq6.6$) galaxies spend as Lyman Break Galaxies (LBGs) with/without Lyman Alpha (Ly\\alpha) emission using a model that combines SPH cosmological simulations (GADGET-2), dust attenuation and a radiative transfer code (pCRASH). The ACFs are a powerful tool that significantly narrows the 3D parameter space allowed by LAE Ly$\\alpha$ and UV luminosity functions (LFs) alone. With this work, we simultaneously constrain the escape fraction of ionizing photons $f_{esc}=0.05-0.5$, the mean fraction of neutral hydrogen in the intergalactic medium (IGM) $\\leq 0.01$ and the dust-dependent ratio of the escape fractions of Ly$\\alpha$ and UV continuum photons $f_\\alpha/f_c=0.6-1.2$. Our results show that reionization has the largest impact on the amplitude of the ACFs, and its imprints are clearly distinguishable from those of $f_{esc}$ and $f_\\alpha/f_c$. We also show that...

  14. An analytical model to calculate absorbed fractions for internal dosimetry with alpha, beta and gamma emitters

    Directory of Open Access Journals (Sweden)

    Ernesto Amato

    2014-03-01

    Full Text Available We developed a general model for the calculation of absorbed fractions in ellipsoidal volumes of soft tissue uniformly filled with alpha, beta and gamma emitting radionuclides. The approach exploited Monte Carlo simulations with the Geant4 code to determine absorbed fractions in ellipsoids characterized by a wide range of dimensions and ellipticities, for monoenergetic emissions of each radiation type. The so-obtained absorbed fractions were put in an analytical relationship with the 'generalized radius', calculated as 3V/S, where V is the ellipsoid volume and S its surface. Radiation-specific parametric functions were obtained in order to calculate the absorbed fraction of a given radiation in a generic ellipsoidal volume. The dose from a generic radionuclide can be calculated through a process of summation and integration over the whole radionuclide emission spectrum, profitably implemented in an electronic spreadsheet. We compared the results of our analytical calculation approach with those obtained from the OLINDA/EXM computer software, finding a good agreement in a wide range of sphere radii, for the high-energy pure beta emitter 90Y, the commonly employed beta-gamma emitter 131I, and the pure alpha emitter 213Po. The generality of our approach makes it useful an easy to implement in clinical dosimetry calculations as well as in radiation safety estimations when doses from internal radionuclide uptake are to be taken into account.

  15. Study on Prostaglandin F/sub 2/sub(. cap alpha. ) in photodermatoses

    Energy Technology Data Exchange (ETDEWEB)

    Horkay, I.; Debreczeni, M.; Krajczar, J.; Csongor, J.; Varga, L.; Mann, V.

    1981-09-01

    Prostaglandin F/sub 2/sub(..cap alpha..) (PGF/sub 2/sub(..cap alpha..)) as a possible mediator was studied. Its plasma content was determined by radioimmunoassay. Changes in the DNA synthesis were followed by autoradiography. In active polymorphous light eruption (PLE) and porphyria cutanea tarda (PCT) a remarkable increase (over 300 pg/ml) in plasma content occurred, especially in cases involving large skin areas. Values returned to normal in remission. PGF/sub 2/sub(..cap alpha..) administered i.d., significantly increased the DNA synthesis of the epidermal cells 48 h after injection similar to the effect of three minimal erythema doses of UV-irradiation. This was more pronounced in PLE patients than in controls. These findings suggest some role of PGF/sub 2/sub(..cap alpha..) in producing the inflammatory and perhaps proliferative components of the skin symptoms in PLE. PGF/sub 2/sub(..cap alpha..) - in parallel to literary data concerning PGE - seems to be a mediator of UV-induced changes in DNA synthesis of the epidermal cells.

  16. Non-linearity between dose and cancer risk for internally deposited alpha emitters in animals

    International Nuclear Information System (INIS)

    The risk of cancer in experimental animals exposed to low doses and dose rates of internally deposited alpha emitting radionuclides was analyzed in 27 animal experiments comprising 78 groups exposed to specific dose levels (dose groups). In these experiments, 3041 animals were exposed to eight different alpha emitters, by injection or by inhalation. Radiation doses ranged from about 60 mGy to more than 7 Gy. There were 1655 control animals. The target organs were the lung and the skeleton. The cancer incidence in exposed groups was compared to that predicted by the Linear No-Threshold Hypothesis (LNTH). In the 3041 exposed animals, 49 cancers were observed, against 83 predicted by the LNTHT. The LNTH appears to be a reliable risk predictor in 11 of the 78 dose groups, but it overestimates the risk in the 67 other dose groups (71 predicted cases, 8 cases observed). No cancer was observed in 53 dose groups, when 23 were predicted by the LNTH. In these 53 dose groups, the probability of not observing a single case of cancer was extremely small. These observations led to the conclusion that, at least in the case of alpha emitters with long physical and biological half-lives, the LNTH is not a good predictor of the risk of cancer. (author)

  17. An Atlas of z=5.7 and z=6.5 Ly alpha Emitters

    CERN Document Server

    Hu, E M; Barger, A J; Capak, P; Kakazu, Y; Trouille, L

    2010-01-01

    We present an atlas of 88 z~5.7 and 30 z~6.5 Ly alpha emitters obtained from a wide-field narrowband survey. We combined deep narrowband imaging in 120A bandpass filters centered at 8150A and 9140A with deep BVRIz broadband imaging to select high-redshift galaxy candidates over an area of 4180 square arcmin. The goal was to obtain a uniform selection of comparable depth over the 7 targeted fields in the two filters. For the GOODS-N region of the HDF-N field, we also selected candidates using a 120A filter centered at 9210A. We made spectroscopic observations with Keck DEIMOS of nearly all the candidates to obtain the final sample of Ly alpha emitters. At the 3.3A resolution of the DEIMOS observations the asymmetric profile for Ly alpha emission with its steep blue fall-off can be clearly seen in the spectra of nearly all the galaxies. We show that the spectral profiles are surprisingly similar for many of the galaxies and that the composite spectral profiles are nearly identical at z=5.7 and z=6.5. We analyze...

  18. Response of neoplastic intestinal vessels to prostaglandin F/sub 2/. cap alpha. : Angiographic observations with emphasis on therapeutic applications

    Energy Technology Data Exchange (ETDEWEB)

    Kusano, S.; Murata, K.; Tominaga, S.; Matsubayashi, T.; Matama, S.; Takahashi, T.

    1983-06-01

    The effects of prostaglandin (PG) F/sub 2/..cap alpha.. in 16 patients with vascular malignant intestinal tumors were analyzed by angiography. It was found that PGF/sub 2/..cap alpha.. reduced tumor vascular flow selectively in all but one patient, a rectal carcinoma case. Among the remaining group, a case of intestinal choriocarcinoma complicated by massive gastrointestinal hemorrhage was successfully controlled with intraarterial infusion of PGF/sub 2/..cap alpha.. into the superior mesenteric artery. Owing to the reduced blood flow in tumors, PGF/sub 2/..cap alpha.. is expected to be used extensively as a vasoconstrictor to control bleeding from tumors of the alimentary tract.

  19. Pressure phase lines and enthalpies for the. cap alpha. -. beta. and. beta. -liquid transitions in beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Abey, A.

    1984-10-31

    The effect of hydrostatic pressure on the ..cap alpha..-..beta.. and ..beta..-liquid transition temperatures in Be was measured in a gas pressure system. Differential thermal analysis was used in the pressure range from 0.1 MPa to 0.7 GPa. For the ..cap alpha..-..beta.. transition, dT/dP = 43 +- 7 K/GPa; for the ..beta..-liquid transition, dT/dP = 35 +- 7 K/GPa. Although it is possible that large systematic errors may arise from experimental procedures, our results are seriously at odds with those of other investigators. Transition enthalpies for the ..cap alpha..-..beta.. and ..beta..-liquid transitions were 1.9 +- 0.2 and 2.2 +- 0.2 kcal/g.m., respectively, at a pressure of 0.1 MPa.

  20. Immuno-vectorization of radioelements emitters of alpha particles: a new therapy in cancerology

    International Nuclear Information System (INIS)

    The radio-immunotherapy is an anti cancerous therapy which consists in vectorising with immuno-specific agents very radio toxic radioelements on tumors or in their environment to destroy them. The first part of this report presents the different characteristics of antibodies as well as their means of production under monoclonal shapes specifically steered against a tumoral antigen of interest. The second part of this report replaces the importance of the immunological vectors in the context of the nuclear medicine. It is notably described that the different methods which allow to radio-label the vector, as well as the different ways of optimization which were envisaged to improve the targeting of radioelements on a tumor. These different developments allow to define the potential place of the alpha radio-immunotherapy in treatments and so re-place the interest of the experimental part. If the radio-immunotherapy, using beta emitters isotopes as the 131iodine or the90yttrium, is today current in anti cancerous therapy, it finds limits because of the disintegration characteristics of the isotopes it uses. Indeed, compared with alpha particles, the beta particles deposit less energy by unit of length in the crossed material.The experimental part of this report aims at studying the feasibility of the coupling between an immunological vector and an alpha emitter isotope.The different tests led on the bismuth 213, the bismuth 212, the lead 212 and the astatine 211 demonstrated that the fixation of these radionuclides was possible. This research theme is strengthened by the construction in Nantes of a cyclotron with high energy ( A.R.R.O.N.A.X.) and the optimization of the obtained promising results should allow a therapeutic use in oncology of the alpha radio-immunotherapy. (N.C.)

  1. Estimates of dose to intraperitoneal micrometastases from alpha and beta emitters in radioimmunotherapy

    International Nuclear Information System (INIS)

    Intraperitoneal metastases from ovarian and other gynecologic tumors are a significant source of treatment failure. In recent years, investigators have used radiolabeled monoclonal antibodies to treat this disease with encouraging results. We have developed a dose calculational technique which generates isodose distributions from intraperitoneally administered alpha and beta particle emitters. In this study we apply the calculations to tissue biopsy samples to determine the adequacy of dose to ovarian micrometastases. Tissue samples from staging biopsies at the time of surgical debulking are scanned to identify small metastases. The patient population studied comprised those with ovarian disease who based on clinical criteria would be considered good candidates for intraperitoneal radioimmunotherapy. The regions of interest (which include the tumor and surface of the peritoneum) are digitized and tumor volumes are contoured. Dose calculations based on the modeling of intraperitoneally administered antibodies radiolabeled with various isotopes is performed and the minimum dose to tumor and normal tissue is assessed. For example, with tumor uptake of 0.1% injected dose per gram of tissue, the surface tumor dose from alpha emitters is up to 45,000 rads. The dose falls to 6000 rads at approximately 40 microns from the peritoneal surface. The surface dose from 20 mCi 90Y administered in 1500 ml saline is up to 10,000 rads, and at a 2-mm depth, approximately 2000 rads. From our calculation dose distribution from radioimmunotherapy varies as a function of physical characteristics of the isotope, absorption of activity, and amount of disease being treated

  2. Lyman-alpha spectral properties of five newly discovered Lyman continuum emitters

    CERN Document Server

    Verhamme, A; Schaerer, D; Izotov, Y; Worseck, G; Thuan, T X; Guseva, N

    2016-01-01

    We have recently reported the discovery of five low redshift Lyman continuum (LyC) emitters (LCEs, hereafter) with absolute escape fractions fesc(LyC) ranging from 6 to 13%, higher than previously found, and which more than doubles the number of low redshift LCEs.We use these observations to test theoretical predictions about a link between the characteristics of the Lyman-alpha (Lya) line from galaxies and the escape of ionising photons. We analyse the Lya spectra of eight LCEs of the local Universe observed with the Cosmic Origins Spectrograph onboard the Hubble Space Telescope (our five leakers and three galaxies from the litterature), and compare their strengths and shapes to the theoretical criteria and comparison samples of local galaxies: the Lyman Alpha Reference Survey, Lyman Break Analogs, Green Peas, and the high-redshift strong LyC leaker Ion2. Our LCEs are found to be strong Lya emitters, with high equivalent widths, EW(Lya)> 70 {\\AA}, and large Lya escape fractions, fesc(Lya) > 20%. The Lya prof...

  3. Alpha particle emitters in cancer therapy: establishing the rationale and overcoming the difficulties

    International Nuclear Information System (INIS)

    rapidly accessible disease. Alpha particles will be most useful in situations in which targeting is rapid, killing of isolated single-cells is important and access to normal tissue is minimized. The latter may be achieved by intracavitary administration or by labeling an agent that does not reach normal tissues before the radionuclide has decayed below an acceptable level. Although alpha-particle emitters have shown promise in animal models, they have not been examined in patients. The decay of 212Bi is accompanied by emission of high energy (2.6 MeV) photons which are difficult to shield; 211At is cyclotron produced and of limited availability. The initial obstacles to the use of alpha-particle emitters for therapy are availability, handling and radiochemistry. These are being overcome with the introduction of new radionuclides and better radiochemistry. Bismuth-213, for example, is similar to Bi-212 in its alpha particle emissions but does not emit the highly energetic photon seen with Bi-212. Once the initial, logistical obstacles are surmounted, the dosimetry and normal tissue toxicity must be investigated

  4. Studies on the atomic and molecular processes produced by alpha emitters in gaseous media using track detection

    International Nuclear Information System (INIS)

    The main purpose of the studies consists in obtaining new and reliable experimental data on certain atomic and molecular physical processes which take place at low speed or/and very low amounts, such as: diffusion, adherence, fallout, etc. of the alpha emitters in gaseous media. By using the track analysis method, most experimental data can be visualized by optical microscopy, so that reliable qualitative and quantitative investigations can be performed. In the first stage, the alpha track method was used. Two plastic detectors were used: CR - 39 (Page, England) and RL - 115 types 1 and 2 (Kodak, France). For these detectors new etching conditions were developed. In the present stage, a calibration of CR - 39 and RL - 115 track detectors for the alpha particles emitted from gaseous radionuclides, particularly for 222 Rn and its alpha descendants, is performed. For this purpose the track detectors were suspended in tight vessels and the following alpha emitter sources were used: - a diuranate source calibrated in uranium prepared in our laboratory; - a calibrated 226 Ra solution; - sources calibrated in 222 Rn and 226 Ra. The amounts and activities of each alpha decay product of these sources are calculated using a radioactive accumulation computation programme UURASE based on the Bateman general equation. The alpha particle ranges were calculated using the TRIM computation programme. In the future stages of this investigation the following studies will be performed: - the diffusion of gaseous alpha emitters; - the sorption of alpha emitter gases and aerosols on different materials; - 222 Rn monitoring in dwelling houses and working places and the implementation of the alpha track method in the National Networks for surveillance of the environmental alpha radioactivity. (authors)

  5. A Search for z=7.3 Ly{\\alpha} Emitters behind Gravitationally Lensing Clusters

    CERN Document Server

    Ota, Kazuaki; Iye, Masanori; Shibuya, Takatoshi; Egami, Eiichi; Kashikawa, Nobunari

    2012-01-01

    We searched for z=7.3 Ly{\\alpha} emitters (LAEs) behind two lensing clusters, Abell 2390 and CL 0024, using the Subaru Telescope Suprime-Cam and a narrowband NB1006 ({\\lambda}c ~ 1005 nm, FWHM ~ 21 nm). Combination of the fully depleted CCDs of the Suprime-Cam, sensitive to z ~ 7 Ly{\\alpha} at ~ 1 {\\mu}m, and magnification by the lensing clusters can be potentially a powerful tool to detect faint distant LAEs. Using NB1006 and deep optical-infrared images taken with the Hubble and Spitzer Space Telescopes, we investigated if there exist objects consistent with the color of z=7.3 LAEs behind the clusters. We could not detect any LAEs to the unlensed Ly{\\alpha} flux limit F(Ly{\\alpha}) ~ 6.9 x 10^{-18} erg s^{-1} cm^{-2}. Comparison with z ~ 7 LAE field searches suggests that a blank field survey covering an area sufficiently larger than lensing clusters is more efficient in finding a large number of z ~ 7 LAEs than both a lensing survey observing many clusters with shallow imaging and a lensing survey imaging ...

  6. Determination the total neutron yields of several semiconductor compounds using various alpha emitters

    Science.gov (United States)

    Abdullah, Ramadhan Hayder; Sabr, Barzan Nehmat

    2016-03-01

    In the present work, the cross-sections of (α,n) reactions available in the literature as a function of α-particle energies for light and medium elements have been rearranged for α-particle energies from near threshold up to 10 MeV in steps of (0.050MeV) using the (Excel and Matlab) computer programs. The obtained data were used to calculate the neutron yields (n/106α) using the quick basic-computer program (Simpson Rules). The stopping powers of alpha particle energies from near threshold to 10 MeV for light and medium elements such as (nat.Be,10B,11B,13C,14N,nat.O,nat.F,nat.Mg,nat.Al,29Si,30Si, nat.P and 46.48Ti) have been calculated using the Zeigler formula. The kinetic energies (Tα) and the branching ratios of each α-emitters such as (211Bi, 210Po, 211Po, 215Po, 217At, 218Rn, 219Rn, 222Rn, 224Ra, 226Ra, 215Th, 228Th, 232U, 234U, 236U, 238U, 238Pu, 239Pu, 241Am, 245Es, 252Fm, 254Fm, 256Fm, 257Fm and 257Md) are taken into consideration to calculate the mean kinetic energy . The polynomial expressions were used to fitting the calculated weighted average of neutron yields (n/106α) for natural light and medium elements such as (Be, B, C, N, O, F, Mg, Al, Si, P and Ti) to determine the adopted neutron yields from the best fitting equation with minimum (CHISQ) at mean kinetic energies of various α-emitters. The total neutron yields (n/s/gx/ppmi) of the mentioned natural light and medium elements have been calculated using the adopted neutron yields (n/106α) from the fitting equations at mean kinetic energies of various α-emitters. The total neutron yields (n/s/gα-emitters/gcompounds) of semiconductor compounds such as (AlN, AlP, BN, BP, SiC, TiO2, BeSiN2, MgCN2, MgSiN2 and MgSiP2) have been calculated by mixing (1gram) of compounds with (1gram) of pure α-emitters using the quick basic computer program. The aim of the present work is to constructed and fabricate the neutron sources theoretically

  7. Alpha Particle Emitter Radiolabeled Antibody for Metastatic Cancer: What Can We Learn from Heavy Ion Beam Radiobiology?

    Directory of Open Access Journals (Sweden)

    Hong Song

    2012-06-01

    Full Text Available Alpha-particle emitter labeled monoclonal antibodies are being actively developed for treatment of metastatic cancer due to the high linear energy transfer (LET and the resulting greater biological efficacy of alpha-emitters. Our knowledge of high LET particle radiobiology derives primarily from accelerated heavy ion beam studies. In heavy ion beam therapy of loco-regional tumors, the modulation of steep transition to very high LET peak as the particle approaches the end of its track (known as the Bragg peak enables greater delivery of biologically potent radiation to the deep seated tumors while sparing normal tissues surrounding the tumor with the relatively low LET track segment part of the heavy ion beam. Moreover, fractionation of the heavy ion beam can further enhance the peak-to-plateau relative biological effectiveness (RBE ratio. In contrast, internally delivered alpha particle radiopharmaceutical therapy lack the control of Bragg peak energy deposition and the dose rate is determined by the administered activity, alpha-emitter half-life and biological kinetics of the radiopharmaceutical. The therapeutic ratio of tumor to normal tissue is mainly achieved by tumor specific targeting of the carrier antibody. In this brief overview, we review the radiobiology of high LET radiations learned from ion beam studies and identify the features that are also applicable for the development of alpha-emitter labeled antibodies. The molecular mechanisms underlying DNA double strand break repair response to high LET radiation are also discussed.

  8. Microscopic study of the /sup 14/O(. cap alpha. ,p)/sup 17/F reactions at stellar energies

    Energy Technology Data Exchange (ETDEWEB)

    Funck, C.; Langanke, K.

    1988-03-28

    We have studied the /sup 14/O(..cap alpha..,p)/sup 17/F reaction at astrophysically important energies within a microscopic multichannel calculation based on the framework of the generator coordinate method. Our study gives a consistent description of the /sup 18/Ne states close to the ..cap alpha..-threshold as well as of the direct (..cap alpha..,p) reaction process which has not been considered in previous calculations. We find that the /sup 14/O(..cap alpha..,p)/sup 17/F rate at temperatures T less than or equal to 5x10/sup 8/ K is strongly influenced by the 2/sup +/ resonance at E = 30 keV above the ..cap alpha..-threshold and by the direct reaction cross section. At higher temperatures /sup 18/Ne states not present in our model space become important. We have estimated the influence of these resonances on the /sup 14/O(..cap alpha..,p)/sup 17/F rate within the standard formalism developed by Fowler assigning experimentally unknown spins to the states on the basis of a Thomas-Ehrman shift analysis using theoretical and experimental informations on the respective analogue states in /sup 18/O. We find an /sup 14/O(..cap alpha..,p)/sup 17/F rate which is noticeably higher than the rate estimated by Wiescher et al. for T less than or equal to 5x10/sup 8/ K. Both rates are of the same magnitude for T greater than or equal to 10/sup 9/ K. Our estimate predicts that the /sup 14/O(..cap alpha..,p)/sup 17/F rate is compatible to the /sup 15/O(..cap alpha..,..gamma..)/sup 19/Ne rate under nova conditions. For explosive burning on accreting neutron stars our rate allows for a break-out from the CNO cycle via the /sup 14/O(..cap alpha..,p)/sup 17/F reaction.

  9. Modelling the Evolution of Ly$\\alpha$ Blobs and Ly$\\alpha$ Emitters

    CERN Document Server

    Smailagić, Marijana; Martinovic, Nemanja

    2016-01-01

    In this work we model the observed evolution in comoving number density of Lyman-alpha blobs (LABs) as a function of redshift, and try to find which mechanism of emission is dominant in LAB. Our model calculates LAB emission both from cooling radiation from the intergalactic gas accreting onto galaxies and from star formation (SF). We have used dark matter (DM) cosmological simulation to which we applied empirical recipes for Ly$\\alpha$ emission produced by cooling radiation and SF in every halo. In difference to the previous work, the simulated volume in the DM simulation is large enough to produce an average LABs number density. At a range of redshifts $z\\sim 1-7$ we compare our results with the observed luminosity functions of LABs and LAEs. Our cooling radiation luminosities appeared to be too small to explain LAB luminosities at all redshifts. In contrast, for SF we obtained a good agreement with observed LFs at all redshifts studied. We also discuss uncertainties which could influence the obtained resul...

  10. On the Use of Ly-alpha Emitters as Probes of Reionization

    CERN Document Server

    Jensen, Hannes; Mellema, Garrelt; Iliev, Ilian T; Sommer-Larsen, Jesper; Shapiro, Paul R

    2012-01-01

    We use numerical simulations to study the effects of the patchiness of a partly reionized intergalactic medium (IGM) on the observability of Ly-alpha emitters (LAEs) at high redshifts (z ~ 6). We present a new model that divides the Ly-alpha radiative transfer into a (circum-)galactic and an extragalactic (IGM) part, and investigate how the choice of intrinsic line model affects the IGM transmission results. We use our model to study the impact of neutral hydrogen on statistical observables such as the Ly-alpha restframe equivalent width (REW) distribution, the LAE luminosity function and the two-point correlation function. We find that if the observed changes in LAE luminosity functions and equivalent width distributions between z ~ 6 and z ~ 7 are to be explained by an increased IGM neutral fraction alone, we require an extremely late and rapid reionization scenario, where the Universe was ~ 40 % ionized at z = 7, ~ 50 % ionized at z = 6.5 and ~ 100 % ionized at z = 6. This is in conflict with other observa...

  11. Narrow-band surveys for very high redshift Lyman-alpha emitters

    CERN Document Server

    Nilsson, Kim K; Lacey, Cedric G; Baugh, Carlton M; Thommes, Eduard

    2007-01-01

    Context: Many current and future surveys aim to detect the highest redshift (z >~ 7) sources through their Lyman-alpha (Ly-alpha) emission, using the narrow-band imaging method. However, to date the surveys have only yielded non-detections and upper limits as no survey has reached the necessary combination of depth and area to detect these very young star forming galaxies. Aims: We aim to calculate model luminosity functions and mock surveys of Ly-alpha emitters at z >~ 7 based on a variety of approaches. Methods: We calculate model luminosity functions at different redshifts based on three different approaches: a semi-analytical model based on CDM, a simple phenomenological model, and an extrapolation of observed Schechter functions at lower redshifts. The results of the first two models are compared with observations made at redshifts z ~ 5.7 and z ~ 6.5, and they are then extrapolated to higher redshift. Results: We present model luminosity functions for redshifts between z = 7 - 12.5 and give specific num...

  12. Studies on the biological effects of internal exposure of alpha emitters. Carcinogenicity test of plutonium

    International Nuclear Information System (INIS)

    Outlines of carcinogenicity tests in animals given with injected or inhaled plutonium (Pu) were described. Insoluble 239PuO2 particles were nasally inhaled in rats maintained for life. The dose response relationship between incidence of their lung tumor and absorbed radiation dose in the lung revealed that>1 Gy dose increased the incidence of malignant lung tumors, which differed from findings in the U.S. probably due to the difference between particle sizes. Further, a carcinogenic mechanism specific for alpha-ray was suggested based on tumor-related gene analysis. After soluble 239Pu (citrate salt) was injected in mice, significant reduction of lifetime and early tumor- or non-tumor-death were observed when the bone dose exceeded 3 Gy. Tumors were mostly osteosarcoma, lymphoma and other soft tissue solid cancers and were different from those induced by gamma-ray, X-ray and neutron irradiation. Studies on the strain difference, on the carcinogenic mechanism and alpha-ray induced mutation and transformation are in progress, which may lead to elucidation of the biological effects of internal exposure of alpha-emitters. (K.H.)

  13. The VLT LBG Redshift Survey - V. Characterising the z = 3.1 Lyman Alpha Emitter Population

    CERN Document Server

    Bielby, R M; Shanks, T; Francke, H; Crighton, N H M; Bañados, E; González-López, Jorge; Infante, L; Orsi, A

    2016-01-01

    We present a survey of Ly$\\alpha$ emitting galaxies in the fields of the VLT LBG Redshift Survey, incorporating the analysis of narrow band number counts, the rest frame UV luminosity function and the two-point correlation function of Ly$\\alpha$ emitters at $z\\approx3.1$. Our photometric sample consists of 750 LAE candidates, over an area of 1.07 deg$^2$, with estimated equivalent widths of $\\gtrsim65$ \\AA, from 5 fields based on deep Subaru Suprime-Cam imaging data. Added to this we have obtained spectroscopic follow-up observations, which successfully detected Ly$\\alpha$ emission in 35 galaxies. Based on the spectroscopic results, we refined our photometric selection constraints, with the resulting sample having a success rate of $78\\pm18\\%$. We calculate the narrow band number counts for our photometric sample and find these to be consistent with previous studies of LAEs at this redshift. We find the $R$-band continuum luminosity function to be $\\sim10\\times$ lower than the equivalent luminosity function o...

  14. Purification of scintillation cocktails containing the alpha emitters americium and plutonium

    International Nuclear Information System (INIS)

    One efficient way of measuring alpha emitters is by the usage of liquid scintillation counting (LSC). A liquid sample is placed in a vial containing a scintillation cocktail. The alpha particles excite electrons in the surrounding liquid, and when they are de-excited photons are emitted. The photons are detected and the activity can be quantified. LSC has a high efficiency for alpha radiation and is therefore a fast and easy way for measuring alpha emitting samples. One drawback is that it does not differentiate very well between alpha energies; measurements of for example curium and plutonium simultaneously are impossible and demand other techniques. Another drawback is the production of a liquid alpha active waste. In Sweden alpha radioactive waste liquids with an activity over some kBq per waste container cannot be sent for final storage. If, however, the activity of the liquids could be reduced by precipitation of the actinides, it would be possible to send away the liquid samples to municipal incineration. In this work a method for a purification of alpha active scintillation cocktails was developed. The method was first tried on a lab scale, and then scaled up. Until today (March, 2013) more than 20 liters of scintillation liquids have successfully been purified from americium and plutonium at Chalmers University of Technology in Sweden. The four scintillation cocktails used were Emulsifier Safe®, Hionic-Fluor®, Ultima Gold AB® and Ultima Gold XR®. The scintillation cocktails could all be purified from americium with higher yield than 95%. The yield was kept when the liquids were mixed. Also plutonium could be precipitated with a yield over 95% in all cocktails except in Hionic-Fluor® (>55%). However, that liquid in particular could be purified (>95%) by mixing it with the three other cocktails. Up-scaling was performed to a batch size of 6-8 L of scintillation cocktail. In neither the americium nor the plutonium system, adverse effects of increasing the

  15. Early bone changes after incorporation of low quantities of alpha emitters in male rats

    International Nuclear Information System (INIS)

    This work shows the early effects of cancergenic doses of alpha emitters in long bones of rats. The investigations were based on radiographic, morphologic, angiographic, histologic and electronmicroscopic methods. A special method for bone angiography in the rat was elaborated and a new method was developed for measurement of the femur neck-head angle. Numerous disturbances in bone growth and bone structure, in the blood supply of bone and also of the bone building cells were observed. There was a correlation between the severity of the damage and the radiation dose, the spacial distribution of the nuclide and partially the age of the rats. The bone injury due to plutonium was markedly reduced by administration of the chelating agent Zn-DTPA. (orig.)

  16. Agonist-promoted desensitization and phosphorylation of. cap alpha. /sub 1/-adrenergic receptors coupled to stimulation of phosphatidylinositol metabolism

    Energy Technology Data Exchange (ETDEWEB)

    Leeb-Lundberg, L.M.F.; Cotecchia, S.; Caron, M.G.; Lefkowitz, R.J.

    1986-03-05

    In the DDT/sub 1/ MF-2 hamster vas deferens smooth muscle cell line the ..cap alpha../sub 1/-adrenergic receptor (..cap alpha../sub 1/-AR) agonist norepinephrine (NE) promotes rapid attenuation of ..cap alpha../sub 1/-AR-mediated phosphatidylinositol (PI) metabolism which is paralleled by rapid phosphorylation of the ..cap alpha../sub 1/-AR. Cells were labeled by incubation with /sup 32/P/sub i/. Coincubation with NE (100 ..mu..M) significantly increases the rate of /sup 32/P-labeling of both PI and phosphatidic acid. Pretreatment of cells with 100 ..mu..M NE (in the presence of 1 ..mu..M propranolol to prevent ..beta..-AR interactions) results in a drastic attenuation of the NE response on PI metabolism. ..cap alpha../sub 1/-AR from labeled cells can be solubilized and purified by affinity chromatography on Affigel-A55414 and wheat germ agglutinin agarose chromatography. SDS-PAGE of purified ..cap alpha../sub 1/-AR shows a NE-promoted increase in phosphorylation of the M/sub r/ 80K ligand binding peptide. Stoichiometry of phosphorylation increases from approx. 1 mol phosphate/mol ..cap alpha../sub 1/-AR in the basal condition to approx. 2.5 after NE treatment. Both desensitization and phosphorylation are rapid being maximal within 10-20 min of agonist exposure. These results together with previous findings that phorbol esters promote rapid ..cap alpha../sub 1/-AR uncoupling and phosphorylation suggest that receptor phosphorylation is an important mechanism of regulation of ..cap alpha../sub 1/-AR receptor responsiveness.

  17. Radiative Transfer Modeling of Lyman Alpha Emitters: I. Statistics of Spectra and Luminosity

    CERN Document Server

    Zheng, Zheng; Trac, Hy; Miralda-Escude, Jordi

    2009-01-01

    We combine a cosmological reionization simulation with box size of 100Mpc/h on a side and a Monte Carlo Lyman-alpha (Lya) radiative transfer code to model Lyman Alpha Emitters (LAEs) at z~5.7. The model introduces Lya radiative transfer as the single factor for transforming the intrinsic Lya emission properties into the observed ones. Spatial diffusion of Lya photons from radiative transfer results in extended Lya emission and only the central part with high surface brightness can be observed. Because of radiative transfer, the appearance of LAEs depends on density and velocity structures in circumgalactic and intergalactic media as well as the viewing angle, which leads to a broad distribution of apparent (observed) Lya luminosity for a given intrinsic Lya luminosity. Radiative transfer also causes frequency diffusion of Lya photons. The resultant Lya line is asymmetric with a red tail. The peak of the Lya line shifts towards longer wavelength and the shift is anti-correlated with the apparent to intrinsic L...

  18. Exploring the nature of the Lyman-$\\alpha$ emitter CR7

    CERN Document Server

    Hartwig, Tilman; Magg, Mattis; Bromm, Volker; Klessen, Ralf S; Glover, Simon C O; Whalen, Daniel J; Pellegrini, Eric W; Volonteri, Marta

    2015-01-01

    CR7 is the brightest Lyman-$\\alpha$ emitter observed at $z>6$, which shows very strong Lyman-$\\alpha$ and HeII 1640 \\AA\\ line luminosities, but no metal line emission. Previous studies suggest that CR7 hosts either young primordial stars with a total stellar mass of $\\sim 10^7\\,\\mathrm{M}_\\odot$ or a black hole of $\\sim 10^6\\,\\mathrm{M}_\\odot$. Here, we explore different formation scenarios for CR7 with a semianalytical model, based on the random sampling of dark matter merger trees. We find that primordial stars cannot account for the observed line luminosities because of their short lifetimes and because of early metal enrichment. Black holes that are the remnants of the first stars are either not massive enough, or reside in metal-polluted haloes, ruling out this possible explanation of CR7. Our models instead suggest that direct collapse black holes, which form in metal-free haloes exposed to large Lyman-Werner fluxes, are more likely the origin of CR7. However, this result is derived under optimistic ass...

  19. The Assay of Alpha- and Beta-Emitters by Means of Scintillating Ion-Exchange Resins

    International Nuclear Information System (INIS)

    The development of scintillating ion.exchange resins (SIER) has provided a unique system for the detection and counting of alpha- and beta-ray emitting nuclides. The property of ion exchange permits the concentration of ionic radionuclides from aqueous solutions of widely varying chemical conditions. The property of scintillation in response to the emitted particles allows for the detection of the adsorbed radionuclides. Both anionic and cationic SIER have been developed and possess the strongly basic, quaternary ammonium group and the strongly acidic, aryl sulphonic group respectively. Therefore, the voluminous literature on the uses of commercially available ion-exchange resins can be applied in many cases to SIER. The availability of both anionic and cationic resins presents the possibility of a method for the adsorption of almost all elements except the rare gases. The stability of SIER is such that it can be used in solution of strong sodium hydroxide, concentrated hydrochloric and sulphuric acids as well as 6N nitric acid at 25°C for short periods (3 - 4 h) of time. SIER is readily adapted for counting with the available scintillation counting apparatus. The activated resin can be counted in a plastic (or glass) cup coupled to a photomultiplier tube and an electronic pulse counter. It can also be transferred to a glass vial, immersed in aqueous alcohol or toluene, and counted in a liquid scintillation counter. SIER in the form of small spherical beads permits the use of counting vessels with many different geometric configurations. Both alpha- and beta-ray emitting nuclides have been efficiently adsorbed and counted using these methods. The low-energy beta-emitters, such as 63Ni and 14C, have been counted with 12 and 35%efficiencies respectively. The alpha-emitters of 239Pu and 237Np have been adsorbed and efficiently counted (70-90%) on both the anionic and cationic resins. 14C-tagged amino acids have also been counted at over 20% efficiency using a liquid

  20. Effect of temperature on interatomic distances in pyroelectric. cap alpha. -LiIO/sub 3/

    Energy Technology Data Exchange (ETDEWEB)

    Coquet, E.; Crettez, J.M. (Laboratoire d' Optique du Reseau Cristallin, Faculte des Sciences, Dijon, France); Pannetier, J.; Bouillot, J. (Institut Max von Laue - Paul Langevin, 38 - Grenoble (France)); Damien, J.C. (Lille-1 Univ., 59 - Villeneuve-d' Ascq (France))

    1983-08-01

    The crystal structure of ..cap alpha..-LiIO/sub 3/ (space group P6/sub 3/) has been refined from neutron and X-ray diffraction data at different temperatures between room temperature and 525 K. The Li atom is well located even at temperatures close to the ..cap alpha.. ..-->.. ..gamma.. phase transition and its thermal parameters do not exhibit any anomalous behaviour. The thermal expansion is analysed in terms of IO/sub 3/-group rotations and expansion of LiO/sub 6/ octahedra; the role of the iodine lone pair in the packing of iodate structures is discussed. The spontaneous polarization is calculated on the basis of a simple point-charge model and the calculated pyroelectric coefficient P/sub 3/ is found to be in fair agreement with the experimental value.

  1. Accumulation of glycation products in. cap alpha. -H pig lens crystallin and its bearing to diabetic cataract genesis

    Energy Technology Data Exchange (ETDEWEB)

    Vidal, P.; Cabezas-Cerrato, J.

    1988-01-01

    The incorporation of /sup 11/C-glucose in native pig crystalline by in vitro incubation was found, after subsequent dialysis, to affect all 5 classes of crystallin separated by Sepharose CL-6B column chromatography. Though the radioactivity of the ..cap alpha..-H fraction was three times greater than that of any of the others, autoradiographs of SDS-PAGE gels showed /sup 11/C-glucose adducts to be present in all soluble protein subunits, without there being any evidence of preferential glycation of the ..cap alpha..-H subunits. The concentration of stable glycation products in the ..cap alpha..-H chromatographic fraction of soluble crystallins is suggested to be due the addition of glycated material to this fraction as result of glycation-induced hyperaggregation, and not because the ..cap alpha..-H subunits were especially susceptible to glycation.

  2. Exploiting 21cm - Ly$\\alpha$ emitter synergies: constraints on reionization

    CERN Document Server

    Hutter, Anne; Müller, Volker; Trott, Cathryn

    2016-01-01

    We couple a $z \\simeq 6.6$ hydrodynamical simulation (GADGET-2) with a radiative transfer code (pCRASH) and a dust model to simultaneously obtain the 21cm emission from the spin-flip transition of neutral hydrogen (HI) as well as the sub-population of galaxies visible as Lyman Alpha Emitters (LAEs). Cross-correlating 21cm data with the underlying galaxy population, and especially the subset visible as LAEs, our aim is to constrain both the average intergalactic medium (IGM) ionization state ($\\langle \\chi_{HI} \\rangle$) and the reionization topology (outside-in versus inside-out). We find that LAEs occupy the densest and most-ionized regions resulting in a very strong anti-correlation between the LAEs and the 21cm emission. Within errors, a 1000h SKA-LOW1 - Subaru Hyper Suprime Cam experiment can provide exquisite constraints on $\\langle \\chi_{HI} \\rangle$, allowing us to distinguish between IGM ionization levels of 50%, 25%, 10% and fully ionized at scales $\\leq 10$ comoving Mpc. Our results support the insi...

  3. The Discovery of Two Lyman$\\alpha$ Emitters Beyond Redshift 6 in the Subaru Deep Field

    CERN Document Server

    Kodaira, K; Kashikawa, N; Kaifu, N; Ando, H; Karoji, H

    2003-01-01

    We have performed a deep optical imaging survey using a narrowband filter ($NB921$) centered at $\\lambda =$ 9196 \\AA ~ together with $i^\\prime$ and $z^\\prime$ broadband filters covering an 814 arcmin$^2$ area of the Subaru Deep Field. We obtained a sample of 73 strong $NB921$-excess objects based on the following two color criteria; $z^\\prime - NB921 > 1$ and $i^\\prime - z^\\prime > 1.3$. We then obtained optical spectroscopy of nine objects in our $NB921$-excess sample, and identified at least two Ly$\\alpha$ emitters at $z \\sim$ 6.5 -- 6.6, each of which shows the characteristic sharp cutoff together with the continuum depression at wavelengths shortward of the line peak. These new data allow us to estimate the first meaningful lower limit of the star formation rate density beyond redshift 6; $\\rho_{\\rm SFR} \\sim 5.2 \\times 10^{-4} M_\\odot$ yr$^{-1}$ Mpc$^{-3}$. Since it is expected that the actual density is higher by a factor of several than this value, our new observation reveals that a moderately high lev...

  4. Quality assurance exercise for estimating low-levels of alpha emitters in urine samples: performance of Trombay's bioassay laboratory

    International Nuclear Information System (INIS)

    As a part of quality assurance, Trombay's bioassay laboratory took part in the international intercomparison exercise organized by International Atomic Energy Agency (IAEA) for estimating low-levels of alpha emitters (234U, 238U, 239+240Pu and 241Am) in urine samples. In this paper, performance of the Trombay's bioassay laboratory in the intercomparison exercise is presented. The results submitted by the laboratory were found to be in good agreement with the organizers (spiked) values. (author)

  5. Critical review for the determination of the minimum detectable activity (MDA) of alpha-emitter radionuclides in environmental samples

    International Nuclear Information System (INIS)

    Different criteria for the calculation of the Minimum Detectable Activity (MDA) of an alpha emitter in environmental levels are reviewed in this report. Practical examples of its application to previously analyzed samples are shown. The authors propose a criteria based on prior calculations that applies to the radiochemical activities performed in the laboratory. The calculation procedure has been discussed with scientist from other laboratories in order to establish a general criteria to calculate the MDA

  6. Alpha-risk or quantification of risks associated with chronic exposure to Alpha emitters; Alpha-risk ou la quantification du risque associe a une exposition chronique aux emeteurs ALPHA

    Energy Technology Data Exchange (ETDEWEB)

    Timarche, M. [Institut de Radioprotection et de Surete Nucleaire, DS, 92 - Fontenay-aux-Roses (France)

    2010-07-15

    This article discusses the results obtained by a European research program on long term health risks associated with a chronic internal contamination by alpha radiation emitters. The researchers outlined that, in the case of an exposure to radon, the lung cancer risk, with respect to the cumulative dose, progressively reduces once the exposure has stopped. They also notice that this risk is present for smokers as well as for not smokers

  7. Capillary electrophoretic study of thiolated alpha-cyclodextrin-capped gold nanoparticles with tetraalkylammonium ions.

    Science.gov (United States)

    Paau, Man Chin; Lo, Chung Keung; Yang, Xiupei; Choi, Martin M F

    2009-11-27

    Capillary zone electrophoresis (CZE) has been employed to characterize nanometer-sized thiolated alpha-cyclodextrin-capped gold nanoparticles (alpha-CD-S-AuNPs). The addition of tetrabutylammonium (Bu(4)N(+)) ions to the run buffer greatly narrows the migration peak of alpha-CD-S-AuNP. The optimal run buffer was determined to be 10mM Bu(4)N(+) in 30 mM phosphate buffer at pH 12 and an applied voltage of 15 kV. The effect of various tetraalkylammonium ions on the peak width and electrophoretic mobility (mu(e)) of alpha-CD-S-AuNP was studied in detail. Bu(4)N(+) ions assist in inter-linking the alpha-CD-S-AuNPs and narrowing the migration peak in CZE. This observation can be explained by the fact that each Bu(4)N(+) ion can simultaneously interact with several hydrophobic cavities of the surface-attached alpha-CDs on AuNPs. The TEM images show that alpha-CD-S-AuNPs with Bu(4)N(+) are linked together but in the absence of Bu(4)N(+), they are more dispersed. The migration mechanism in CZE is based on the formation of inclusion complexes between Bu(4)N(+) and alpha-CD-S-AuNPs which induces changes in the charge-to-size ratio of alpha-CD-S-AuNPs and mu(e). An inverse linear relationship (r(2)>0.998) exists between the mu(e) and size of alpha-CD-S-AuNPs in the core range 1.4-4.1 nm. The CZE analyses are rapid with migration time less than 4 min. A few nanoliters of each of the alpha-CD-S-AuNP samples were injected hydrodynamically at 0.5 psi for 5s. Our work confirms that CZE is an efficient tool for characterizing the sizes of alpha-CD-S-AuNPs using Bu(4)N(+) ions. PMID:19853853

  8. Comparative analysis of inelastic interactions of protons, deuterons, and. cap alpha. particles with nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Barashenkov, V.S.; Zheregi, F.G.; Musul' manbekov, Z.Z.; Plyushchev, V.A.; Solov' eva, Z.I.

    1981-04-01

    Inelastic interactions of protons, deuterons, and ..cap alpha.. particles with emulsion nuclei at 3.6 Gev/nucleon are analyzed within the framework of the cascade-evaporation model. The model accounts well, within the limits of experimental error, for all the principal characteristics measured in experiment; in particular, it explains why the energy of the g protons emitted into the rear hemisphere is independent of the emission angle of these protons, of the mass of the primary particle, and of the degree of spallation of the target nucleus. Some discrepancy with experiment manifests itself only in the details.

  9. Involvement of prostaglandins F/sub 2. cap alpha. / and E/sub 1/ with rabbit endometrium

    Energy Technology Data Exchange (ETDEWEB)

    Orlicky, D.J.

    1985-01-01

    Several growth factors and hormones are thought to play a role in the growth control of endometrial cells. The authors have shown that prostaglandin F/sub 2..-->../ (PGF/sub 2..cap alpha../) is a growth factor for primary cultures of rabbit endometrium cultured in chemically-defined serum-free medium and that prostaglandin E/sub 1/ (PGE/sub 1/) antagonizes the PGF/sub 2..-->../ induction of growth. Both (/sup 3/H)PGF/sub 2..cap alpha../ and (/sup 3/H)PGE/sub 1/ bind in a time and temperature dependent, dissociable, saturable and specific manner. The binding of (/sup 3/H)PGF/sub 2..cap alpha../ and (/sup 3/H)PGE/sub 1/ can be both down and up regulated and is enzyme sensitive. PGE /sub 1/ stimulates intracellular cAMP synthesis and accumulation in a time and concentration dependent manner. PGF/sub 2..cap alpha../ probably exerts its effects through an amiloride-sensitive intermediate. Both PGF/sub 2..cap alpha../ and PGE/sub 1/ are constitutively synthesized by these primary cultures, and they have shown this synthesis to be both drug and hormone sensitive. They hypothesize that it is the ratio, rather than the absolute quantities, of PGF/sub 2..cap alpha../ and PGE/sub 1/ which is of more importance in the regulation of endometrial cell growth. Furthermore, they believe this regulation of endometrial growth plays a role in control of proliferation during the decidual response and that a derangement in the ratio of these prostaglandins may lead to either infertility or hyperplasia. The ability of these cultures to synthesize prostaglandins in a hormonally regulatable manner may be of importance in the study of dysmenorrhea and uterine cramping as caused by the myometrial contracting prostaglandin, PGF/sub 2..cap alpha../.

  10. Herschel reveals the obscured star formation in HiZELS H\\alpha\\ emitters at z=1.47

    CERN Document Server

    Ibar, E; Best, P N; Ivison, R J; Smail, I; Arumugam, V; Berta, S; Béthermin, M; Bock, J; Cava, A; Conley, A; Farrah, D; Floc'h, E Le; Lutz, D; Magdis, G; Magnelli, B; Ikarashi, S; Kohno, K; Marsden, G; Oliver, S J; Page, M J; Pozzi, F; Riguccini, L; Schulz, B; Seymour, N; Smith, A J; Symeonidis, M; Wang, L; Wardlow, J; Zemcov, M

    2013-01-01

    We describe the far-infrared (FIR; rest-frame 8--1000\\mu m) properties of a sample of 443 H\\alpha-selected star-forming galaxies in the COSMOS and UDS fields detected by the HiZELS imaging survey. Sources are identified using narrow-band filters in combination with broad-band photometry to uniformly select H\\alpha\\ (and [OII] if available) emitters in a narrow redshift slice at z = 1.47+/-0.02. We use a stacking approach in Spitzer, Herschel (from PEP and HerMES surveys) and AzTEC images to describe their typical FIR properties. We find that HiZELS galaxies with observed H\\alpha\\ luminosities of ~ 10^{8.1-9.1} Lo have bolometric FIR luminosities of typical LIRGs, L_FIR ~ 10^{11.48+/-0.05} Lo. Combining the H\\alpha\\ and FIR luminosities, we derive median SFR = 32+/-5 Mo/yr and H\\alpha\\ extinctions of A(H\\alpha) = 1.0+/-0.2 mag. Perhaps surprisingly, little difference is seen in typical HiZELS extinction levels compared to local star-forming galaxies. We confirm previous empirical stellar mass (M*) to A(H\\alpha...

  11. The BOSS Emission-Line Lens Survey. III. : Strong Lensing of Ly$\\alpha$ Emitters by Individual Galaxies

    CERN Document Server

    Shu, Yiping; Kochanek, Christopher S; Oguri, Masamune; Perez-Fournon, Ismael; Zheng, Zheng; Mao, Shude; Montero-Dorta, Antonio D; Brownstein, Joel R; Marques-Chaves, Rui; Menard, Brice

    2016-01-01

    We introduce the BOSS Emission-Line Lens Survey (BELLS) GALaxy-Ly$\\alpha$ EmitteR sYstems (BELLS GALLERY) Survey, which is a Hubble Space Telescope program to image a sample of galaxy-scale strong gravitational lens candidate systems with high-redshift Ly$\\alpha$ emitters (LAEs) as the background sources. The goal of the BELLS GALLERY Survey is to illuminate dark substructures in galaxy-scale halos by exploiting the small-scale clumpiness of rest-frame far-UV emission in lensed LAEs, and to thereby constrain the slope and normalization of the substructure mass function. In this paper, we describe in detail the spectroscopic strong-lens selection technique, which is based on methods adopted in the previous Sloan Lens ACS (SLACS) Survey, BOSS Emission-Line Lens Survey, and SLACS for the Masses Survey. We present the BELLS GALLERY sample of the 21 highest-quality galaxy-LAE candidates selected from $\\approx 1.4 \\times 10^6$ galaxy spectra in the Baryon Oscillation Spectroscopic Survey (BOSS) of the Sloan Digital...

  12. Reaction of HO/sub 2//O/sub 2//sup -/ with. cap alpha. -tocopherol in ethanolic solutions

    Energy Technology Data Exchange (ETDEWEB)

    Arudi, R.L.; Sutherland, M.W.; Bielski, B.H.J.

    1982-01-01

    The HO/sub 2/ perhydroxyl radical reacts with ..cap alpha..-tocopherol in 85% ethanol containing some H/sub 2/SO/sub 4/, EDTA, and O/sub 2/. The resulting transient has a spectral maximum near 390 ..mu... The final product is mostly ..cap alpha..-tocopherylquinone. Best reproducibility for reaction of O/sub 2//sup -/ with ..cap alpha..-tocopherol was obtained in a deoxygenated reaction mixture of 26 +- 3 ..mu..M O/sub 2//sup -/, 0.0565M ..cap alpha..-tocopherol, 5..mu..M EDTA, and 0.005 M KOH in 85% EtOH; the upper limit for the reaction was 6.0 +- 3.0 M/sup -1/ s/sup -1/, indicating that for all practical purposes O/sub 2//sup -/ does not react at all with ..cap alpha..-tocopherol. Preliminary experiments with Trolox, a vitamin E model compound, indicates that it too reacts with HO/sub 2/ but not with O/sub 2//sup -/. Membrane-bound tocopherols in vivo may fulfil a dual antioxidant role. (DLC)

  13. Secondary. cap alpha. -deuterium kinetic isotope effects in solvolyses of ferrocenylmethyl acetate and benzoate in ethanol

    Energy Technology Data Exchange (ETDEWEB)

    Sutic, D. (Univ. of Zagreb, Yugoslavia); Asperger, S.; Borcic, S.

    1982-12-17

    Secondary ..cap alpha..-deuterium kinetic isotope effects (KIE) in solvolyses of ferrocenyldideuteriomethyl acetate and benzoate were determined in 96% (v/v) ethanol, at 25/sup 0/C, as k/sub H//k/sub D/ = 1.24 and 1.26, respectively. The KIEs were also determined in the presence of 0.1 mol dm/sup -3/ lithium perchlorate: the k/sub H//k/ sub D/ values were 1.23 and 1.22 for acetate and benzoate complexes, respectively. The maximum KIE for the C-O bond cleavage of a primary substrate is as large as, or larger than, that of secondary derivatives, which is estimated to be 1.23 per deuterium. The measured KIE of about 12% per D therefore represents a strongly reduced effect relative to its maximum. The solvolyses exhibit ''a special salt effect''. This effect indicates the presence of solvent-separated ion pairs and the return to tight pairs. As the maximum KIE is expected in solvolyses involving transformation of one type of ion pair into another, the strongly reduced ..cap alpha..-D KIE supports the structure involving direct participation of electrons that in the ground state are localized at the iron atom. The alkyl-oxygen cleavage is accompanied by 10-15% acyl-oxygen cleavage.

  14. Removal of. cap alpha. -tocopherol from blood and its comparison with other lipids

    Energy Technology Data Exchange (ETDEWEB)

    Gardner, H.K.; Vang, M.J.; Mavis, R.D.

    1986-01-01

    The blood decay curve of ..cap alpha..-tocopherol in rats was compared with those of the two major blood lipids by labeling rat serum in vitro with /sup 3/H-..cap alpha..-tocopherol (AT), /sup 3/H-cholesterol (CHO) or /sup 3/H-trioleoylglycerol (TO) and injecting it into the bloodstream. For the three lipids, loss from blood was biphasic. The half time of the faster decay was 2-4 minutes. The slower curve decayed with half times of 42, 289 and 990 minutes for TO, AT and CHO, respectively. This intermediate rate of AT removal is consistent with its accompanying both of the major blood lipids as they are removed by their respective mechanisms or with a process specific for AT. To investigate the role of liver in the faster curve, animals were hepatectomized. TO and CHO loss remained biphasic after liver removal. However, AT loss became monophasic, with a loss rate intermediate between the non-hepatectomized fast and slow decays. This demonstrates a central role for liver in the metabolism of blood-borne AT and a mode of removal distinct from the other two lipids.

  15. Lyman Alpha Emitters at z=7 in the Subaru/XMM-Newton Deep Survey Field: Photometric Candidates and Luminosity Function

    CERN Document Server

    Ota, Kazuaki; Kashikawa, Nobunari; Shimasaku, Kazuhiro; Ouchi, Masami; Totani, Tomonori; Kobayashi, Masakazu A R; Nagashima, Masahiro; Harayama, Atsushi; Kodaka, Natsuki; Morokuma, Tomoki; Furusawa, Hisanori; Tajitsu, Akito; Hattori, Takashi

    2010-01-01

    We conducted a deep narrowband NB973 (FWHM = 200 A centered at 9755 A) survey of z=7 Lyman alpha emitters (LAEs) in the Subaru/XMM-Newton Deep Survey Field, using the fully depleted CCDs newly installed on the Subaru Telescope Suprime-Cam, which is twice more sensitive to z=7 Lyman alpha at ~ 1 micron than the previous CCDs. Reaching the depth 0.5 magnitude deeper than our previous survey in the Subaru Deep Field that led to the discovery of a z=6.96 LAE, we detected three probable z=7 LAE candidates. Even if all the candidates are real, the Lyman alpha luminosity function (LF) at z=7 shows a significant deficit from the LF at z=5.7 determined by previous surveys. The LAE number and Lyman alpha luminosity densities at z=7 is ~ 7.7-54% and ~5.5-39% of those at z=5.7 to the Lyman alpha line luminosity limit of L(Ly-alpha) >~ 9.2 x 10^{42} erg s^{-1}. This could be due to evolution of the LAE population at these epochs as a recent galaxy evolution model predicts that the LAE modestly evolves from z=5.7 to 7. How...

  16. The most luminous H$\\alpha$ emitters at z~0.8-2.23 from HiZELS: evolution of AGN and star-forming galaxies

    CERN Document Server

    Sobral, David; Best, Philip N; Smail, Ian; Harrison, Chris M; Stott, John; Calhau, João; Matthee, Jorryt

    2016-01-01

    We use new near-infrared spectroscopic observations to investigate the nature and evolution of the most luminous H\\alpha (Ha) emitters at z~0.8-2.23, which evolve strongly in number density over this period, and compare them to more typical Ha emitters. We study 59 luminous Ha emitters with $L_{H\\alpha}>L_{H\\alpha}^*$, roughly equally split per redshift slice at z~0.8, 1.47 and 2.23 from the HiZELS and CF-HiZELS surveys. We find that, overall, 30$\\pm$8% are AGN (80$\\pm$30% of these AGN are broad-line AGN, BL-AGN), and we find little to no evolution in the AGN fraction with redshift, within the errors. However, the AGN fraction increases strongly with Ha luminosity and correlates best with $L_{H\\alpha}/L_{H\\alpha}^*(z)$. While $L_{H\\alpha}80%), the most luminous Ha emitters ($L_{H\\alpha}>10L_{H\\alpha}^*(z)$) at any cosmic time are essentially all BL-AGN. Using our AGN-decontaminated sample of luminous star-forming galaxies, and integrating down to a fixed Ha luminosity, we find a factor of ~1300x evolution in ...

  17. Some applications of Photon/Electron-Rejecting Alpha Liquid Scintillation (PERALS) spectrometry to the assay of alpha emitters

    International Nuclear Information System (INIS)

    The combination of certain solvent extraction separations and a special kind of liquid scintillation detector and electronics designed for alpha spectrometry allows some highly accurate, yet simple determinations of alpha-emitting nuclides. Counting efficiency is 99.68% with backgrounds of 99.95%. The Photon/Electron Rejecting Alpha Liquid Scintillation (PERALS) equipment is described and procedures for the separation and determination of uranium, thorium, plutonium, polonium, radium, and trivalent actinides are outlined. 25 refs., 10 figs., 1 tab

  18. Treatment of solid waste highly contaminated by alpha emitters: recent developments of leaching process with continuous electrolyte regeneration

    International Nuclear Information System (INIS)

    Development of processes for leaching solid waste contaminated by alpha or alpha/beta/gamma emitters has been pursued at the Nuclear Research Center in Fontenay-aux-Roses, France with the recent active commissioning of two pilot facilities: the Elise glove box system in February 1987 and the Prolixe shielded hot cell in March 1988. The Elise facility is designed to handle alpha waste and the Prolixe facility is designed to handle alpha/beta/gamma waste. The common goal of the studies conducted in these facilities is to define the operating conditions for declassification of solid waste, i.e. to ensure that the alpha concentration of this waste will be less than 3.7 x 106 Bq/kg after treatment, packaging and decay prior to storage in surface repositories. The leaching process developed is mainly based on the continuous electrolytic regeneration of an aggressive agent, AgII, which can induce the dissolution of PuO2, the most difficult compound to remove from the solid waste. This paper summarizes recent achievements in the development of this process

  19. Lyman-\\alpha{} Emitters in the context of hierarchical galaxy formation: predictions for VLT/MUSE surveys

    CERN Document Server

    Garel, Thibault; Blaizot, Jérémy

    2015-01-01

    The VLT Multi Unit Spectroscopic Explorer (MUSE) integral-field spectrograph can detect Ly\\alpha{} emitters (LAE) in the redshift range $2.8 \\lesssim z \\lesssim 6.7$ in a homogeneous way. Ongoing MUSE surveys will notably probe faint Ly\\alpha{} sources that are usually missed by current narrow-band surveys. We provide quantitative predictions for a typical wedding-cake observing strategy with MUSE based on mock catalogs generated with a semi-analytic model of galaxy formation coupled to numerical Ly\\alpha{} radiation transfer models in gas outflows. We expect $\\approx$ 1500 bright LAEs ($F_{Ly\\alpha}$ $\\gtrsim$ $10^{-17}$ erg s$^{-1}$ cm$^{-2}$) in a typical Shallow Field (SF) survey carried over $\\approx$ 100 arcmin$^2$, and $\\approx$ 2,000 sources as faint as $10^{-18}$ erg s$^{-1}$ cm$^{-2}$ in a Medium-Deep Field (MDF) survey over 10 arcmin$^2$. In a typical Deep Field (DF) survey of 1 arcmin$^2$, we predict that $\\approx$ 500 extremely faint LAEs ($F_{Ly\\alpha}$ $\\gtrsim$ $4 \\times 10^{-19}$ erg s$^{-1}$...

  20. The HETDEX Pilot Survey V: The Physical Origin of Lyman-alpha Emitters Probed by Near-infrared Spectroscopy

    CERN Document Server

    Song, Mimi; Gebhardt, Karl; Hill, Gary J; Drory, Niv; Ashby, Matthew L N; Blanc, Guillermo A; Bridge, Joanna; Chonis, Taylor; Ciardullo, Robin; Fabricius, Maximilian; Fazio, Giovanni G; Gawiser, Eric; Gronwall, Caryl; Hagen, Alex; Huang, Jia-Sheng; Jogee, Shardha; Livermore, Rachael; Salmon, Brett; Schneider, Donald P; Willner, S P; Zeimann, Gregory R

    2014-01-01

    We present the results from a VLT/SINFONI and Keck/NIRSPEC near-infrared spectroscopic survey of 16 Lyman-alpha emitters (LAEs) at $z$ = 2.1 - 2.5 in the COSMOS and GOODS-N fields discovered from the HETDEX Pilot Survey. We detect rest-frame optical nebular lines (H$\\alpha$ and/or [OIII]$\\lambda$5007) for 10 of the LAEs and measure physical properties, including the star formation rate (SFR), gas-phase metallicity, gas-mass fraction, and Ly$\\alpha$ velocity offset. We find that LAEs may lie below the mass-metallicity relation for continuum-selected star-forming galaxies at the same redshift. The LAEs all show velocity shifts of Ly$\\alpha$ relative to the systemic redshift ranging between +85 and +296 km s$^{-1}$ with a mean of +180 km s$^{-1}$. This value is smaller than measured for continuum-selected star-forming galaxies at similar redshifts. The Ly$\\alpha$ velocity offsets show a moderate correlation with the measured star formation rate (2.5$\\sigma$), but no significant correlations are seen with the SFR...

  1. DNA double strand breaks as predictor of efficacy of the alpha-particle emitter Ac-225 and the electron emitter Lu-177 for somatostatin receptor targeted radiotherapy.

    Directory of Open Access Journals (Sweden)

    Franziska Graf

    Full Text Available RATIONALE: Key biologic effects of the alpha-particle emitter Actinium-225 in comparison to the beta-particle emitter Lutetium-177 labeled somatostatin-analogue DOTATOC in vitro and in vivo were studied to evaluate the significance of γH2AX-foci formation. METHODS: To determine the relative biological effectiveness (RBE between the two isotopes (as - biological consequence of different ionisation-densities along a particle-track, somatostatin expressing AR42J cells were incubated with Ac-225-DOTATOC and Lu-177-DOTATOC up to 48 h and viability was analyzed using the MTT assay. DNA double strand breaks (DSB were quantified by immunofluorescence staining of γH2AX-foci. Cell cycle was analyzed by flow cytometry. In vivo uptake of both radiolabeled somatostatin-analogues into subcutaneously growing AR42J tumors and the number of cells displaying γH2AX-foci were measured. Therapeutic efficacy was assayed by monitoring tumor growth after treatment with activities estimated from in vitro cytotoxicity. RESULTS: Ac-225-DOTATOC resulted in ED50 values of 14 kBq/ml after 48 h, whereas Lu-177-DOTATOC displayed ED50 values of 10 MBq/ml. The number of DSB grew with increasing concentration of Ac-225-DOTATOC and similarly with Lu-177-DOTATOC when applying a factor of 700-fold higher activity compared to Ac-225. Already 24 h after incubation with 2.5-10 kBq/ml, Ac-225-DOTATOC cell-cycle studies showed up to a 60% increase in the percentage of tumor cells in G2/M phase. After 72 h an apoptotic subG1 peak was also detectable. Tumor uptake for both radio peptides at 48 h was identical (7.5%ID/g, though the overall number of cells with γH2AX-foci was higher in tumors treated with 48 kBq Ac-225-DOTATOC compared to tumors treated with 30 MBq Lu-177-DOTATOC (35% vs. 21%. Tumors with a volume of 0.34 ml reached delayed exponential tumor growth after 25 days (44 kBq Ac-225-DOTATOC and after 21 days (34 MBq Lu-177-DOTATOC. CONCLUSION: γH2AX-foci formation, triggered

  2. Theory of the induction of bone sarcoma by bone-seeking alpha emitters and its application to risk assessment

    International Nuclear Information System (INIS)

    This work discusses the theory of bone sarcoma induction by bone seeking alpha emitters, which is based strictly on biological considerations relative to the mechanism of radiation-induced carcinogenesis, identification of cells at risk and their location in bone, bone tissue renewal processes and bone cell kinetics with or without radiation exposure. The model is consistent with the data on bone sarcoma incidence human with incorporated long-lived isotopes Ra-226 + Ra-228. Extrapolation of these data to a low intake region of the basis of the developed theoretical approach suggests that the linear ICRP-UNSCEAR model overestimates carciogenic risk at low doses, possibly by a factor of 2-4. The model suggests a linear response of target cells to the initiation effects of alpha irradiation. The non-linear (linear-quadratic) initial part of dose-response curve for osteosarcoma induction is explained quantitatively by a model based on a promoter effect of regenerative hyperplasia resulting from invitation effects of alpha radiation. The maximum overestimation inherent to the model of the low-level risk due to the the dose-dependent promotion factor is estimated using bo+1/bo, where bo is a model parameter which is proportional to the normal division rate of osteogenic cells in vivo and which can be estimated within the framework of the model. The model provides confirming evidence that, for radiation protection purposes, endosteal cells may be considered the only group of cells at risk of sarcoma induction by low doses of bone-seeking alpha emitters, whereas the role of marrow stromal (osteogenic) cells as target cells is much more significant with increasing intakes, and can become dominating if intake is high enough

  3. Theory of the induction of bone sarcoma by bone-seeking alpha emitters and its application to risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    Petojan, I.M.

    1992-06-01

    This work discusses the theory of bone sarcoma induction by bone seeking alpha emitters, which is based strictly on biological considerations relative to the mechanism of radiation-induced carcinogenesis, identification of cells at risk and their location in bone, bone tissue renewal processes and bone cell kinetics with or without radiation exposure. The model is consistent with the data on bone sarcoma incidence human with incorporated long-lived isotopes Ra-226 + Ra-228. Extrapolation of these data to a low intake region of the basis of the developed theoretical approach suggests that the linear ICRP-UNSCEAR model overestimates carciogenic risk at low doses, possibly by a factor of 2-4. The model suggests a linear response of target cells to the initiation effects of alpha irradiation. The non-linear (linear-quadratic) initial part of dose-response curve for osteosarcoma induction is explained quantitatively by a model based on a promoter effect of regenerative hyperplasia resulting from invitation effects of alpha radiation. The maximum overestimation inherent to the model of the low-level risk due to the the dose-dependent promotion factor is estimated using bo{sup +1}/bo, where bo is a model parameter which is proportional to the normal division rate of osteogenic cells in vivo and which can be estimated within the framework of the model. The model provides confirming evidence that, for radiation protection purposes, endosteal cells may be considered the only group of cells at risk of sarcoma induction by low doses of bone-seeking alpha emitters, whereas the role of marrow stromal (osteogenic) cells as target cells is much more significant with increasing intakes, and can become dominating if intake is high enough.

  4. Similarities and uniqueness of Ly$\\alpha$ emitters among star-forming galaxies at z=2.5

    CERN Document Server

    Shimakawa, Rhythm; Shibuya, Takatoshi; Kashikawa, Nobunari; Tanaka, Ichi; Matsuda, Yuichi; Tadaki, Ken-ichi; Koyama, Yusei; Hayashi, Masao; Suzuki, Tomoko L; Yamamoto, Moegi

    2016-01-01

    We conducted a deep narrow-band imaging survey with the Subaru Prime Focus Camera on the Subaru Telescope and constructed a sample of Ly$\\alpha$ emitters (LAEs) at z=2.53 in the UDS-CANDELS field where a sample of H$\\alpha$ emitters (HAEs) at the same redshift is already obtained from our previous narrow-band observation at NIR. The deep narrow-band and multi broadband data allow us to find LAEs of stellar masses and star-formation rates (SFRs) down to $\\gtrsim$$10^8$ M$_\\odot$ and $\\gtrsim$0.2 M$_\\odot$/yr, respectively. We show that the LAEs are located along the same mass-SFR sequence traced by normal star-forming galaxies such as HAEs, but towards a significantly lower mass regime. Likewise, LAEs seem to share the same mass--size relation with typical star-forming galaxies, except for the massive LAEs, which tend to show significantly compact sizes. We identify a vigorous mass growth in the central part of LAEs: the stellar mass density in the central region of LAEs increases as their total galaxy mass gr...

  5. Conception and optimisation of a new apparatus for the radioactive aerosols alpha emitters measurement in real time

    International Nuclear Information System (INIS)

    The measurement of the atmospheric contaminations due to artificial radioelements alpha emitters (239 Pu, 241 Am, 244 Cm,...) is a very difficult problem to resolve because of the three following reasons: the nature of the radiation to detect; very small activities, which correspond to LDCA; existence in the atmosphere of descendants radon and thoron, which are alpha emitters too. To avoid the drawbacks that the present apparatus present, we have conceived, realised and focused a new apparatus based on the following principals: aerosols collection by gas jet technic on solid state support and measurement in real time under a few millibar pression using a solid detector. First of all, we have tried to make the aerosol collection rate better studying the collector nature and dimension influence, the distance between the collector and the gas jet exit and the air flow. Using different supports, we have shown that the energy resolution is not depending on the support nature, but it depends very much on atmospheric conditions. Direct measurements of the radioactive samples are made by the annular detector insered between the nozzle and the collector. The good resolution, the efficacity and the discrimination of natural and artificial contaminations show off the feasibility of this apparatus

  6. Analysis of alpha emitters in the coral, Favites virens, from Bikini lagoon by solid-state track detection

    International Nuclear Information System (INIS)

    A quantitative method for the non-destructive analysis of alpha emitters in CaCO3 matrices by solid-state track detection in cellulose nitrate was developed. 0.4pCi/g in an area of 4 mm2 can be measured routinely; smaller concentrations can be determined but with a lower resolution. Calibration methods used were a Pu source of 0.15 μCi in conjunction with polycarbonate and CaCO3 absorbers of different thickness, 2-30 μm, and a powdered coral sample from Enewetak Atoll which had been radiochemically analyzed for plutonium radionuclides, 241Am and other long-lived fission and activation products. Slabs of a coral, Favites virens, from Bikini lagoon were analyzed. A quantity of the alpha emitters detected in regions of the coral identified with growth during the years of nuclear testing, 1954, 1956 and 1959, are found in small discrete spots. Thin sections cut parallel to the direction of coral growth give different patterns of distribution. No such hot spots are evident in any post-test year growth sections although plutonium and other long lived fission and activation products were measured in these sections by radiochemical techniques. (author)

  7. Some applications of Photon/Electron-Rejecting Alpha Liquid Scintillation (PERALS) spectrometry to the assay of alpha emitters

    Energy Technology Data Exchange (ETDEWEB)

    McDowell, W.J.; Case, G.N.

    1988-01-01

    The combination of certain solvent extraction separations and a special kind of liquid scintillation detector and electronics designed for alpha spectrometry allows some highly accurate, yet simple determinations of alpha-emitting nuclides. Counting efficiency is 99.68% with backgrounds of <0.02 cpm. Energy resolution and peak position are sufficient for the identification of many nuclides. Rejection of interference from ..beta.. and ..gamma.. radiation is >99.95%. The Photon/Electron Rejecting Alpha Liquid Scintillation (PERALS) equipment is described and procedures for the separation and determination of uranium, thorium, plutonium, polonium, radium, and trivalent actinides are outlined. 25 refs., 10 figs., 1 tab.

  8. Clinical use of bone-targeting radiopharmaceuticals with focus on alpha-emitters

    Institute of Scientific and Technical Information of China (English)

    Hinrich; A; Wieder; Michael; Lassmann; Martin; S; Allen-Auerbach; Johannes; Czernin; Ken; Herrmann

    2014-01-01

    Various single or multi-modality therapeutic options are available to treat pain of bone metastasis in patients with prostate cancer.Different radionuclides that emitβ-rays such as 153Samarium and 89Strontium and achieve palliation are commercially available.In contrast toβ-emitters,223Radium as a a-emitter has a short path-length.The advantage of the a-emitter is thus a highly localized biological effect that is caused by radiation induced DNA double-strand breaks and subsequent cell killing and/or limited effectiveness of cellular repair mechanisms.Due to the limited range of the a-particles the bone surface to red bone marrow dose ratio is also lower for 223Radium which is expressed in a lower myelotoxicity.The a emitter 223Radium dichloride is the first radiopharmaceutical that significantly prolongslife in castrate resistant prostate cancer patients with wide-spread bone metastatic disease.In a phaseⅢ,randomized,double-blind,placebo-controlled study 921patients with castration-resistant prostate cancer and bone metastases were randomly assigned.The analysis confirmed the 223Radium survival benefit compared to the placebo(median,14.9 mo vs 11.3 mo;P<0.001).In addition,the treatment results in pain palliation and thus,improved quality of life and a delay of skeletal related events.At the same time the toxicity profile of223Radium was favourable.Since May 2013,223Radium dichloride(Xofigo?)is approved by the US Food and Drug Administration.

  9. Absolute measurements of the alpha-gamma emitters activities by a sum-coincidence method

    International Nuclear Information System (INIS)

    The absolute activity of U-235 contained in a UO2 sample, using a sum-coincidence circuit which selected only the alpha particles which were simultaneous with the well known 184 Kev gamma radiation from Th-231. The alpha particles were detected by ZnS(Ag) scintillator specially designed to show its maximun efficiency for U-235 alpha particles, whereas the gamma radiation was detected by NaI(Tl) scintillation detector. The values obtained for the half-life of U-235 was compared with data from various observers using different experimental techniques. (Author)

  10. Improved method for the complete separation of gross alpha and beta emitters in drinking water

    International Nuclear Information System (INIS)

    During this work, a modified methodology for the separation of gross alpha and beta activity from potable water is proposed. Laboratory spiked experiments show a recovery of gross radioactivity in the range of 98-99% with the proposed methodology. The detection limits using this methodology are 20mBq/l and 2mBq/l for gross beta and alpha respectively. These detection limits are two order of magnitude lower than the maximum acceptable concentration of gross alpha and gross beta activity i.e. less than 0.5/(0.1) Bq/L and 1 Bq/L, respectively. (author)

  11. A Dual Narrowband Survey for H\\alpha\\ Emitters at z=2.2: Demonstration of the Technique and Constraints on the H\\alpha\\ Luminosity Function

    CERN Document Server

    Lee, Janice C; Spitler, L; Labbe, I; Salim, S; Persson, S E; Ouchi, M; Dale, D; Monson, A; Murphy, D

    2012-01-01

    We present first results from a narrowband imaging program for intermediate redshift emission-line galaxies using the newly commissioned FourStar infrared camera at the 6.5m Magellan telescope. To enable prompt identification of H\\alpha\\ emitters, a pair of custom 1% filters, which sample low-airglow atmospheric windows at 1.19 \\mu m and 2.10 \\mu m, is used to detect both H\\alpha\\ and [OII]\\lambda 3727 emission from the same redshift volume at z=2.2. Initial observations are taken over a 130 arcmin^2 area in the CANDELS-COSMOS field. The exquisite image quality resulting from the combination of the instrument, telescope, and standard site conditions (~0.55" FWHM) allows the 1.19 \\mu m and 2.10 \\mu m data to probe 3\\sigma\\ emission-line depths down to 1.0e-17 erg/s/cm^2 and 1.2e-17 erg/s/cm^2 respectively, in less than 10 hours of integration time in each narrowband. For H\\alpha\\ at z=0.8 and z=2.2, these fluxes correspond to observed star formation rates of ~0.3 and ~4 Msun/yr respectively. We find 122 source...

  12. Dosimetry of natural and man-made alpha emitters in plankton

    International Nuclear Information System (INIS)

    Comparison between the natural and man-made alpha radiation dose rates to plankton can be important for predicting the potential long-term effects on aquatic biota resulting from the routine or accidental radioactive releases from the nuclear fuel cycle. A contribution is made here towards the goal of comparing natural with man-made alpha radiation dose rates to plankton using the same method of calculation in both cases. (Author)

  13. On the decreasing fraction of Strong Ly$\\alpha$ Emitters around $z$ $\\sim$ $6$-$7$

    CERN Document Server

    Sadoun, Raphael; Miralda-Escudé, Jordi

    2016-01-01

    The fraction of galaxies with strong Ly$\\alpha$ emission has been observed to decrease rapidly with redshift at $z \\ge 6$, after a gradual increase at $z6$. We study this effect by modeling the ionization and Ly$\\alpha$ radiative transfer in the infall region and the IGM around a Ly$\\alpha$ emitting galaxy (LAE), for a spherical halo model with the mean density and radial velocity profiles in the standard $\\Lambda$CDM cosmological scenario. We find that the expected fast increase of the ionizing background intensity toward the end of the reionization epoch implies a rapid evolution of halo infall regions from being self-shielded against the external ionizing background to being mostly ionized. Whereas self-shielded infall regions can scatter the Ly$\\alpha$ photons over a much larger area than the commonly used apertures for observing LAEs, the same infalling gas is no longer optically thick to the Ly$\\alpha$ emission line after it is ionized by the external background, making the Ly$\\alpha$ emission more comp...

  14. Toxin a from Clostridium difficile binds to rabbit erythrocyte glycolipids with therminal Gal. cap alpha. 1-3Gal. beta. 1-4GlcNaC sequences

    Energy Technology Data Exchange (ETDEWEB)

    Clark, G.F.; Krivan, H.; Wilkins, T.; Smith, D.F.

    1987-05-01

    Toxin A is one of two clostridial toxins implicated as the causative agent of pseudomembranous colitis in patients undergoing postoperative antibiotic therapy. Evidence that the carbohydrate binding determinant for this toxin is a glycoconjugate(s) with non-reducing Gal..cap alpha..1-3Gal..beta..1-4GlcNAc has recently been reported. Specific agglutination of rabbit erythrocytes by Toxin A is inhibited by bovine thyroglobulin and prevented by pretreatment of cells with ..cap alpha..-galactosidase. Total lipid extracts from rabbit erythrocytes were subjected to thin layer chromatography and the chromatogram overlaid with purified /sup 125/I-labeled Toxin A. Two major and several minor toxin-binding glycolipids were detected following autoradiography. The major toxin-binding glycolipids were identified as pentasaccharide- and decasaccharide-ceramides expressing terminal Gal..cap alpha..1-3Gal..beta..1-4GlcNAc sequences. Treatment of the toxin-binding glycolipids with ..cap alpha..-galactosidase abolished binding. Forsmann glycolipid, globoside, Gal..cap alpha..1-4 Gal..beta..1-4Glc-cer, and Gal..cap alpha..1-3Gal..beta..1-4Glc-cer did not bind the toxin. These observations are consistent with the proposed carbohydrate specificity of the toxin for the non-reducing terminal sequence, Gal..cap alpha..1-3Gal..beta..1-4GlcNAc.

  15. Application of centralized networked low background gross alpha counters for the determination of radioactivity from alpha emitters

    International Nuclear Information System (INIS)

    The separation of Pu-isotopes in bioassay samples has been carried out by standardized analytical procedures of bioassay programme at Health Physics Laboratory, Tarapur. The separated Pu activity is measured using centralized networked low background gross alpha counters. The paper describes the aspects of estimating Pu-isotopes in urine samples using new networked system of ten gross alpha counters based on ZnS (Ag) detector. The minimum detectable activity of the system for urine samples is estimated as 0.37 mBq/day. The methodology leads to a standard uncertainty of 14% in urinary excreted activity of Pu at levels as low as 1 mBq/day due to low background and 15 days counting. The performance and its use for urine samples containing low levels due to chronic intake of actinides is indicated. (author)

  16. Removal of. cap alpha. -tocopherol from blood and its comparison with other lipids: studies of inhibition

    Energy Technology Data Exchange (ETDEWEB)

    Gardner, H.K.; Mavis, R.D.

    1986-05-01

    To investigate the mechanism of ..cap alpha..-tocopherol (AT) uptake into tissues, loss of /sup 3/H-AT from blood was characterized and compared with the losses of two major blood lipids: /sup 3/H-cholesterol (CHO) and /sup 3/H-trioleoylglycerol (TO). Male Long-Evans rats (200-325 gm) were injected with serum labelled with one lipid, and bled from the tail from 1-240 min. In one group heparin (HEP), an inhibitor of lipoprotein lipase which mediates uptake of TO into tissues, was intravenously injected prior to serum and following corn oil gavage. The control group was only gavaged (GAV). A third group was injected with labelled serum which had been incubated with 1,2-cyclohexanedione (CHD), a reagent which modifies the receptors responsible for removal of CHO-rich low density lipoproteins from blood. Labelled serum incubated only with borate buffer (BO) was injected into the fourth group. HEP slowed TO loss from 2-220 min, but left CHO loss unchanged. AT loss was slowed by HEP from 100 min on. That AT responded to HEP but over a time span different from that of TO suggests that AT may be removed by a mechanism distinct from that of TO but sensitive to HEP. CHD slowed CHO loss from 40-240 min while TO and AT loss were uninhibited. This argues against a mechanism of removal common to both AT and CHO.

  17. An Ultraluminous Lyman Alpha Emitter with a Blue Wing at z=6.6

    CERN Document Server

    Hu, E M; Songaila, A; Barger, A J; Rosenwasser, B; Wold, I

    2016-01-01

    We report the detection of the most luminous high-redshift Lyman Alpha Emitting galaxy (LAE) yet seen, with log L(Ly alpha) = 43.9 ergs/s. The galaxy -- COSMOS Lyman alpha 1, or COLA1 -- was detected in a search for ultra-luminous LAEs with Hyper Suprime-Cam on the Subaru telescope. It was confirmed to lie at z = 6.593 based on a Lyman alpha line detection obtained from followup spectroscopy with the DEIMOS spectrograph on Keck2. COLA1 is the first very high-redshift LAE to show a multi-component Lyman alpha line profile with a blue wing, which suggests that it could lie in a highly ionized region of the intergalactic medium and could have significant infall. If this interpretation is correct, then ultra-luminous LAEs like COLA1 offer a unique opportunity to determine the properties of the HII regions around these galaxies which will help in understanding the ionization of the z ~ 7 intergalactic medium.

  18. Effect of alpha-radiolysis on the dissolution of UO2 doped with alpha emitters under anoxic conditions

    International Nuclear Information System (INIS)

    The α emissions constitute almost entirely the radiation field of spent nuclear fuel after 500 years in a geological repository. In this work the effect of α-radiolysis on the fuel dissolution in the near field was studied. Pellets of UO2 doped with 10% wt. and 0.1% wt. of ''238 Pu (α-emitter) were prepared using a solgel method which provides homogenous distribution of the dopant in the UO2 matrix. The sintered materials were extensively characterized. Static leaching tests on these materials were carried out under anoxic conditions in deaerated water at room temperature. The results show that the uranium release from the matrix increase for the higher dopant concentration. Under the experimental conditions used it was difficult to observe a clear radiolysis effect on dissolution of the material containing 0.1% wt. of ''238 Pu. In order to study the radiation damage due to α decay in the fluorite type lattice of the UO2, the variation of the lattice parameter as a function of time was measured. An increase of the lattice parameter of approx 0,2% was observed after 1,5 months of storage in the UO2 doped with 10% wt. of plutonium. In the case of the UO2 doped with 0,1% wt. ''238 Pu, the lattice parameter did not vary significantly during the same time interval. The possible effects of damage accumulation on UO2 dissolution are discussed. (Author) 7 refs

  19. A Cose Comparison between Observed and modeled Ly{\\alpha} Lines for z ~ 2.2 Lyman Alpha Emitters

    CERN Document Server

    Hashimoto, Takuya; Ouchi, Masami; Shimasaku, Kazuhiro; Schaerer, Daniel; Nakajima, Kimihiko; Shibuya, Takatoshi; Rauch, Michael; Ono, Yoshiaki; Goto, Ryosuke

    2015-01-01

    We present the results of a Lya profile analysis of 12 Lya emitters (LAEs) at z = 2.2 with high-resolution Lya spectra. We find that all 12 objects have a Lya profile with the main peak redward of the systemic redshift defined by nebular lines, and five have a weak, secondary peak blueward of the systemic redshift (blue bump). The average velocity offset of the red main peak (the blue bump, if any) with respect to the systemic redshift is Delta_v_Lya,r = 174+/- 19 km s-1 (Delta_v_Lya,b = -316+/-45 km s-1), which is smaller than (comparable to) that of Lyman-break galaxies (LBGs). The outflow velocities inferred from metal absorption lines in three individual and one stacked spectra are comparable to those of LBGs. The expanding shell model constructed by Verhamme et al. (2006) reproduces not only the Lya profiles but also other observed quantities including the outflow velocity and the FWHM of nebular lines for the non-blue bump objects. On the other hand, the model predicts too high FWHMs of nebular lines fo...

  20. Kinetics of ozonation. 4. Reactions of ozone with. cap alpha. -tocopherol and oleate and linoleate esters in carbon tetrachloride and in aqueous micellar solvents

    Energy Technology Data Exchange (ETDEWEB)

    Giamalva, D.H.; Church, D.F.; Pryor, W.A.

    1986-10-15

    Vitamin E (..cap alpha..-tocopherol; ..cap alpha..-T) is known to protect animals against the deleterious effects of ozone in polluted air; one such effect is the ozone-initiated autooxidation of polyunsaturated fatty acids (PUFA) that occur in membranes. In order to assess the possibility of a direct reaction of ozone with ..cap alpha..-T competing with the very fast ozone-PUFA reaction, we have measured the rates of reaction of ozone with ..cap alpha..-T, oleic acid, and linoleic acid. I CCl/sub 4/ as solvent, ..cap alpha..-T reacts with ozone with a rate constant of about 5500 M/sup -1/ s/sup -1/; methyl oleate and methyl linoleate react 2 orders of magnitude faster. In aqueous micellar solutions the rate constants for ..cap alpha..-T and the fatty acids are more similar. The k for the ozone/..cap alpha..-T reaction is about 1 x 10/sup 6/ M/sup -1/ s/sup -1/ at pH 7, but decreases as the solution becomes more acidic; the k's for oleic acid and linoleic acid are ca. 1 x 10/sup 6/ M/sup -1/ s/sup -1/ and exhibit no significant pH dependence. Since the ratio of fatty acids to ..cap alpha..-T in membranes is typically at least 100-1000 to 1, we conclude that the direct reaction of ozone with ..cap alpha..-T is unlikely. Thus, the protection that vitamin E provides to animals breathing ozone-containing air must result from vitamin E acting as a free radical scavenger. We have also detected the ..cap alpha..-tocopheroxyl radical as an intermediate from the reaction of ozone with ..cap alpha..-T both in CCl/sub 4/ and aqueous micelles using electron spin resonance spectroscopy. The authors suggest that the observation of this intermediate is consistent with an initial electron transfer from ..cap alpha..-T to ozone.

  1. The WUW ML bundle detector A flow through detector for alpha-emitters

    CERN Document Server

    Wenzel, U; Lochny, M

    1999-01-01

    Using conventional laboratory ware, we designed and manufactured a flow through cell for monitoring alpha-bearing solutions. The cell consists of a bundle of thermoplastic, transparent tubes coated with a thin layer of the meltable scintillator MELTILEX sup T sup M at the inner surface. With appropriate energy windows set, the detector can suppress beta-particles to a great extent due to its geometrical dimensions. For pure alpha-solutions, the detection limits are 5 Bq/ml, for composite nuclide mixtures, the detector is capable to monitor the decontamination of medium active waste (<=10 sup 7 Bq/ml) down to 100 Bq alpha/g solution. At a throughput of 1 ml/s, the pressure build-up amounts to approx 2 bar. We have developed a quality control program to ensure the regularity of the individual bundle loops.

  2. Purification of used scintillation liquids containing the alpha emitters americium and plutonium

    International Nuclear Information System (INIS)

    In Sweden, alpha radioactive waste liquids with an activity over some kBq per waste container cannot be sent for final storage. Therefore, in this work, a method for a purification of alpha active scintillation cocktails was developed. Until today (March, 2013) more than 20 L of scintillation liquids have successfully been purified from americium and plutonium. The products of the process are a solid fraction that can be sent to final storage and a practically non-radioactive liquid fraction that can be sent to municipal incineration. (author)

  3. Mobility parameters for the vacancies and the self-interstitials in concerntrated. cap alpha. -AgZn alloys

    Energy Technology Data Exchange (ETDEWEB)

    Beretz, D.; Hillairet, J.; Halbwachs, M. (CEA Centre d' Etudes Nucleaires de Grenoble, 38 (France). Dept. de Recherche Fondamentale)

    1981-10-01

    Influx relaxation measurements were carried out to monitor the radiation enhanced Zener ordering rate in a Ag-9 at. % Zn alloy. From consideration of both the quasistationary and the stationary rates it is inferred that the vacancies are the faster diffusers, with activation energy close to 0.60 eV. More generally, the migration properties of the point defects in the whole range of the concentrated ..cap alpha..-solid solutions of the AgZn system are presented and discussed.

  4. Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code 10

    International Nuclear Information System (INIS)

    Clinical practices for neoplastic disease diagnose and treatment are based on the incorporation of α, β and γ radiotracers and radiopharmaceuticals, which might be associated with potential damage. Thus, being necessary accurate dosimetry strategies. In vivo absorbed dose appears as an ideal solution. However, its implementation in clinics does not attain enough reliability. On the other hand, different approaches were proposed for internal dosimetry calculations. Some special analytical methodologies were developed by the Committee on Medical Internal Radiation Dose (MIRD) to assess organ level dose values in nuclear medicine. Improvements in informatics achieve better computation performance, but Monte Carlo approaches for patient-specific dosimetry are sometimes high time-consuming l imitating its use in routine clinical practices. Analytical approaches introduce kernel convolution techniques aimed to patient spe ci dosimetry. Although scattering effects are not accurately handled, these methods are capable of fast dosimetry computation based on photon Energy Deposition Kernel (EDK and particle Dose Point Kernel (DPK) assessed for radionuclides in order to perform further dosimetry calculations. EDK and DPK are obtained according to specific source emission. It was considered a point source isotropically emitting within an homogeneous medium, so that radiation transport is accounted as uniformly distributed over concentric spherical regions by shell tally. Dedicated Monte Carlo simulations were performed by a subroutine adapted from the FLUKA co se. In water EDK were evaluated at different photon energies and some typical γ-emitters radiopharmaceuticals; whereas DPK were obtained for both α and β emitters. Additionally, EDK and DPK were calculated for several biological tissues. Obtained results agree with energy loss from stopping power calculated by Bethe-Bark as- Bloch theory in the continuous slowing down approximation

  5. RADIOACTIVE POSITRON EMITTER PRODUCTION BY ENERGETIC ALPHA PARTICLES IN SOLAR FLARES

    International Nuclear Information System (INIS)

    Measurements of the 0.511 MeV positron-annihilation line from solar flares are used to explore the flare process in general and ion acceleration in particular. In flares, positrons are produced primarily by the decay of radioactive positron-emitting isotopes resulting from nuclear interactions of flare-accelerated ions with ambient solar material. Kozlovsky et al. provided ion-energy-dependent production cross sections for 67 positron emitters evaluated from their threshold energies (some <1 MeV nucleon–1) to a GeV nucleon–1, incorporating them into a computer code for calculating positron-emitter production. Adequate cross-section measurements were available for proton reactions, but not for α-particle reactions where only crude estimates were possible. Here we re-evaluate the α-particle cross sections using new measurements and nuclear reaction codes. In typical large gamma-ray line flares, proton reactions dominate positron production, but α-particle reactions will dominate for steeper accelerated-ion spectra because of their relatively low threshold energies. With the accelerated-3He reactions added previously, the code is now reliable for calculating positron production from any distribution of accelerated-ion energies, not just those of typical flares. We have made the code available in the online version of the Journal. We investigate which reactions, projectiles, and ion energies contribute to positron production. We calculate ratios of the annihilation-line fluence to fluences of other gamma-ray lines. Such ratios can be used in interpreting flare data and in determining which nuclear radiation is most sensitive for revealing acceleration of low-energy ions at the Sun

  6. RADIOACTIVE POSITRON EMITTER PRODUCTION BY ENERGETIC ALPHA PARTICLES IN SOLAR FLARES

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, R. J. [Code 7650, Naval Research Laboratory, Washington, DC 20375 (United States); Kozlovsky, B. [Tel Aviv University, Tel Aviv (Israel); Share, G. H., E-mail: murphy@ssd5.nrl.navy.mil, E-mail: benz@wise.tau.ac.il, E-mail: share@astro.umd.edu [University of Maryland, College Park, MD 20742 (United States)

    2015-01-01

    Measurements of the 0.511 MeV positron-annihilation line from solar flares are used to explore the flare process in general and ion acceleration in particular. In flares, positrons are produced primarily by the decay of radioactive positron-emitting isotopes resulting from nuclear interactions of flare-accelerated ions with ambient solar material. Kozlovsky et al. provided ion-energy-dependent production cross sections for 67 positron emitters evaluated from their threshold energies (some <1 MeV nucleon{sup –1}) to a GeV nucleon{sup –1}, incorporating them into a computer code for calculating positron-emitter production. Adequate cross-section measurements were available for proton reactions, but not for α-particle reactions where only crude estimates were possible. Here we re-evaluate the α-particle cross sections using new measurements and nuclear reaction codes. In typical large gamma-ray line flares, proton reactions dominate positron production, but α-particle reactions will dominate for steeper accelerated-ion spectra because of their relatively low threshold energies. With the accelerated-{sup 3}He reactions added previously, the code is now reliable for calculating positron production from any distribution of accelerated-ion energies, not just those of typical flares. We have made the code available in the online version of the Journal. We investigate which reactions, projectiles, and ion energies contribute to positron production. We calculate ratios of the annihilation-line fluence to fluences of other gamma-ray lines. Such ratios can be used in interpreting flare data and in determining which nuclear radiation is most sensitive for revealing acceleration of low-energy ions at the Sun.

  7. Use of a large gridded ionization chamber for identification of alpha emitters samples

    International Nuclear Information System (INIS)

    This paper refers to a large magnitude gridded ionization chamber with high resolution used in the identification of alpha radioactive samples. Several values of α energy were found which matched perfectly well adjustment curve of the chamber. Many other additional measures using different kinds of adjusted detectors were successfully obtained in order to confirm the results gotten in the experiments, thus leading to the identification of some elements of the 233 U radioactive series. (author). 10 refs., 4 figs., 1 tab

  8. Nuclide identification of alpha-emitters by autoradiography in specimen of atomic victims at Nagasaki

    OpenAIRE

    Shichijo, Kazuko; Takatsuji, Toshihiro; Yamamoto, Masayoshi; Nakashima, Masahiro

    2012-01-01

    The explosion of a plutonium Atomic bomb over Nagasaki city in Japan took place at 1102h on August 9, 1945. Radiation dose of A-bomb survivor is practically estimated from external radiation. The alpha particles can be disregarded science they travel only a short distance through air. Plutonium remaining in the soil at Nagasaki after 24yr has been determined in 1971. In the patients subjected to the Atomic bomb there was no evidence of the introduction of radioactive material. We have already...

  9. A New Population of High Redshift, Dusty Lyman-Alpha Emitters and Blobs Discovered by WISE

    CERN Document Server

    Bridge, Carrie R; Borys, Colin J K; Petty, Sara; Benford, Dominic; Eisenhardt, Peter; Farrah, Duncan; Griffith, Roger L; Jarrett, Tom; Stanford, S Adam; Stern, Daniel; Tsai, Chao-Wei; Wright, Edward L; Wu, Jingwen

    2012-01-01

    We report a new technique to select 1.610^{13-14}L_sun) and warm colors, typically larger than submillimeter-selected galaxies (SMGs) and dust-obscured galaxies (DOGs). These traits are commonly associated with the dust being energized by intense AGN activity. We hypothesize that the combination of spatially extended Lyman-alpha, large amounts of warm IR-luminous dust, and rarity (implying a short-lived phase) can be explained if the galaxies are undergoing strong `feedback' transforming them from an extreme dusty starburst to a QSO.

  10. Use of proportional gas scintillator in absolute measurements of alpha-gamma emitter activities

    International Nuclear Information System (INIS)

    The absolute activity of U-235 contained in a U3 O8 sample was measured utilizing a sum-coincidence circuit which selects only the alpha particles which are simultaneous with the 143 KeV and 186 KeV gamma radiations from the Th-231 (product nucleus). The alpha particles were detected by means of a new type of a gas scintillating chamber, in which the light emitted by excitation of the gas atoms, due to the passage of a charged incoming particle, has its intensity increased by the action of an applied electric field. The gamma radiations were detected by means of a NaI(Tl) 1'' x 11/2'' scintillation detector. The value obtained for the half-life of U-235 was compared with the data available from various observers which used different experimental techniques. It is shown tht the results, are in excellent agreement with the best international data available on the subject and that, therefore, the sum-coincidence technique constitutes an important method for such measurements. (Author)

  11. The clustering of Lyman alpha emitters at z=7: implications for reionization and host halo masses

    CERN Document Server

    Sobacchi, Emanuele

    2015-01-01

    The Ly$\\alpha$ line of high-redshift galaxies has emerged as a powerful probe of both early galaxy evolution and the epoch of reionization (EoR). Motivated by the upcoming wide-field survey with the Subaru Hyper Supreme-Cam (HSC), we study the angular correlation function (ACF) of narrow-band selected, $z\\approx7$ LAEs. The clustering of LAEs is determined by both: (i) their typical host halo masses, $\\bar{M}_{\\rm h}$; (ii) the absorption due to a patchy EoR, characterized by an average neutral fraction of the IGM, $\\bar{x}_{\\rm HI}$. We bracket the allowed LAE ACF by exploring extreme scenarios for both the intrinsic Ly$\\alpha$ emission and the morphology of cosmic ionized patches in physical EoR models. Current LAE ACF measurements imply that the Universe is mostly ionized at $z\\approx7$, with $\\bar{x}_{\\rm HI}\\lesssim0.5$ (1-$\\sigma$) even for an extremely conservative model of intrinsic emission. The upcoming Ultra Deep campaign with the HSC could improve on these constraints by tens of percent, or $\\bar{...

  12. Spectroscopic Properties of the z=4.5 Lyman-alpha Emitters

    CERN Document Server

    Dawson, S; Malhotra, S; Stern, D; Dey, A; Spinrad, H; Jannuzi, B T; Wang, J X; Wang, E; Dawson, Steve; Rhoads, James E.; Malhotra, Sangeeta; Stern, Daniel; Dey, Arjun; Spinrad, Hyron; Jannuzi, Buell T.; Wang, JunXian; Wang, Emily

    2004-01-01

    We present Keck/LRIS optical spectra of 17 Lya-emitting galaxies and one Lyman break galaxy at z=4.5 discovered in the Large Area Lyman Alpha (LALA) survey. The survey has identified a sample of ~350 candidate Lya-emitting galaxies at z=4.5 in a search volume of 1.5 x 10^6 comoving Mpc^3. We targeted 25 candidates for spectroscopy; hence, the 18 confirmations presented herein suggest a selection reliability of 72%. The large equivalent widths (median W(rest)~80 A) but narrow physical widths (v 240 A, exceeding the maximum Lya equivalent width predicted for normal stellar populations. Nonetheless, we find no evidence for HeII 1640 emission in either individual or composite spectra, indicating that though these galaxies are young, they are not truly primitive, Population III objects.

  13. Morphological Properties of Lyman Alpha Emitters at Redshift 4.86 in the COSMOS Field: Clumpy Star Formation or Merger?

    CERN Document Server

    Kobayashi, Masakazu A R; Koekemoer, Anton M; Murayama, Takashi; Taniguchi, Yoshiaki; Kajisawa, Masaru; Shioya, Yasuhiro; Scoville, Nick Z; Nagao, Tohru; Capak, Peter L

    2016-01-01

    We investigate morphological properties of 61 Lyman-alpha emitters (LAEs) at z = 4.86 identified in the COSMOS field, based on Hubble Space Telescope Advanced Camera for Surveys (ACS) imaging data in the F814W-band. Out of the 61 LAEs, we find the ACS counterparts for the 54 LAEs. Eight LAEs show double-component structures with a mean projected separation of 0."63 (~ 4.0 kpc at z = 4.86). Considering the faintness of these ACS sources, we carefully evaluate their morphological properties, that is, size and ellipticity. While some of them are compact and indistinguishable from the PSF half-light radius of 0."07 (~ 0.45 kpc), the others are clearly larger than the PSF size and spatially extended up to 0."3 (~ 1.9 kpc). We find that the ACS sources show a positive correlation between ellipticity and size and that the ACS sources with large size and round shape are absent. Our Monte Carlo simulation suggests that the correlation can be explained by (1) the deformation effects via PSF broadening and shot noise or...

  14. Impact of Cosmic Variance on the Galaxy-Halo Connection for Lyman-$\\alpha$ Emitters

    CERN Document Server

    Mejia-Restrepo, Julian E

    2016-01-01

    In this paper we study the impact of cosmic variance and observational uncertainties in constraining the mass and occupation fraction, $f_{\\rm occ}$, of dark matter halos hosting Ly-$\\alpha$ Emitting Galaxies (LAEs) at high redshift. To this end, we construct mock catalogs from an N-body simulation to match the typical size of observed fields at $z=3.1$ ($\\sim 1 {\\rm deg^2}$). In our model a dark matter halo with mass in the range $M_{\\rm min}

  15. Cross-correlation of the cosmic 21-cm signal and Lyman Alpha Emitters during reionization

    CERN Document Server

    Sobacchi, Emanuele; Greig, Bradley

    2016-01-01

    Interferometry of the cosmic 21-cm signal is set to revolutionize our understanding of the Epoch of Reionization (EoR), eventually providing 3D maps of the early Universe. Initial detections however will be low signal-to-noise, limited by systematics. To confirm a putative 21-cm detection, and check the accuracy of 21-cm data analysis pipelines, it would be very useful to cross-correlate against a genuine cosmological signal. The most promising cosmological signals are wide-field maps of Lyman alpha emitting galaxies (LAEs), expected from the Subaru Hyper-Suprime Cam (HSC) Ultra-Deep field. Here we present estimates of the correlation between LAE maps at z~7 and the 21-cm signal observed by both the Low Frequency Array (LOFAR) and the planned Square Kilometer Array Phase 1 (SKA1). We adopt a systematic approach, varying both: (i) the prescription of assigning LAEs to host halos; and (ii) the large-scale structure of neutral and ionized regions (i.e. EoR morphology). We find that the LAE-21cm cross-correlation...

  16. High-LET alpha-emitters: Radon, lung cancer and smoking

    International Nuclear Information System (INIS)

    The National Academy of Sciences BEIR IV Report deals with the health effects in human populations exposed to internally-deposited alpha-emitting radionuclides and their decay products. Quantitative risk estimates for cancer induction are derived, mainly from analyses of epidemiological data. The Report addresses the health outcomes of exposure to radon and its daughters, primarily lung cancer risks of worker exposure to radon progeny in underground mines and in the general public in indoor domestic environments. An excess relative risk model of lung cancer mortality and exposure to radon progeny is developed; this models the excess risk per Working Level Month in terms of time intervals prior to an attained age, and is dependent on time-since-exposure and age at risk. Risk projections are presented and cover exposure situations of current public health concern. For example, lifetime exposure to 1 WLM y/sup /minus/1/ is estimated to increase the number of deaths due to lung cancer by a factor of about 1.5 over the current rate for both males and females in a population having the current prevalence of cigarette-smoking. Occupational exposure to 4 WLM y/sup /minus/1/ from ages 20 y to 40 y is projected to increase lung cancer deaths by a factor of 1.6 over the current rate of this age cohort in the general population. In all of these cases, most of the increased risk occurs to smokers for whom the risk is up to ten times greater than for non-smokers. 8 refs., 1 tab

  17. Continuous three-dimensional radiation dosimetry in tissue-equivalent phantoms using electron paramagnetic resonance in L-. cap alpha. -alanine

    Energy Technology Data Exchange (ETDEWEB)

    Wielopolski, L.; Maryanski, M.; Ciesielski, B.; Forman, A.; Reinstein, L.E.; Meek, A.G.

    1987-07-01

    A new tissue-equivalent phantom material has been developed which also acts as a dosimeter. The new phantom material has a similar elemental composition to that of soft tissue and has a density 1.1 g/cm/sup 3/. The phantom has an agar-gel base, and contains crystallized L-..cap alpha..-alanine which traps radiation-induced free radicals. Samples from the phantom were analyzed by an electron paramagnetic resonance (EPR) spectrometer and the intensity of the EPR signal was related to the absorbed dose. When calibrated, the phantom material acts as a dosimeter, with applications in radiation therapy.

  18. Immunochemical detection of a primase activity related subunit of DNA polymerase. cap alpha. from human and mouse cells using the monoclonal antibody

    Energy Technology Data Exchange (ETDEWEB)

    Yagura, T.; Kozu, T.; Seno, T.; Tanaka, S.

    1987-12-01

    A hybrid cell line (HDR-854-Er) secreting monoclonal antibody (E4 antibody) against a subunit of human DNA polymerase ..cap alpha.. was established by immunizing mice with DNA replicase complex (DNA polymerase ..cap alpha..-primase complex) prepared from HeLa cells. The E4 antibody immunoprecipitates DNA replicase complex from both human and mouse cells. The E4 antibody neutralized the primase activity as assessed either by the direct primase assay (incorporation of (..cap alpha..-/sup 32/P)AMP) or by assay of DNA polymerase activity coupled with the primase activity using unprimed poly(dT) as a template. The E4 antibody does not neutralize DNA polymerase ..cap alpha.. activity with the activated calf thymus DNA as a template. Western immunoblotting analysis shows that the E4 antibody binds to a polypeptide of 77 kilodaltons (kDa) which is tightly associated with DNA polymerase ..cap alpha... The 77-kDa polypeptide was distinguished from the catalytic subunit (160 and 180 kDA) for DNA synthesis which was detected by another monoclonal antibody, HDR-863-A5. Furthermore, it is unlikely that the 77-kDa peptide is the primase, since we found that the E4 antibody also immunoprecipitates the mouse 7.3 S DNA polymerase ..cap alpha.. which has no primase activity, and Western immunoblotting analysis shows that the 77-kDa polypeptide is a subunit of the 7.3S DNA polymerase ..cap alpha... Furthermore, after dissociation of the primase from mouse DNA replicase by chromatography on a hydroxyapatite column in the presence of dimethyl sulfoxide and ethylene glycol, the 77-kDA polypeptide is associated with DNA polymerase ..cap alpha.., and not with the primase. These results indicate that the 77-kDa polypeptide detected with the E4 antibody is not the primase but is a subunit firmly bound to DNA polymerase ..cap alpha.. catalytic polypeptide and yet influences the activity of the associated DNA primase.

  19. Amino acid sequence of phospholipase A/sub 2/-. cap alpha. from the venom of Crotalus adamanteus

    Energy Technology Data Exchange (ETDEWEB)

    Heinrikson, R.L.; Krueger, E.T.; Keim, P.S.

    1977-07-25

    The complete amino acid sequence of Crotalus adamanteus venom phospholipase A/sub 2/-..cap alpha.. has been determined by analysis of the five tryptic peptides from the citraconylated, reduced, and S-(/sup 14/C)carboxamidomethylated enzyme. Earlier studies provided the information necessary to align the tryptic fragments so that secondary cleavage procedures to establish overlaps were unnecessary. The subunit in the phospholipase A/sub 2/-..cap alpha.. dimer is a single polypeptide chain containing 122 amino acids and seven disulfide bonds. The histidine residue implicated in the active site of mammalian phospholipases is at position 47 in the C. adamanteus enzyme and is located in a domain of the molecule which is highly homologous in sequence with corresponding regions of phospholipases from a variety of venom and pancreatic sources. Comparative sequence analysis has revealed insights with regard to the function and evolution of phospholipases A/sub 2/. Primary structural relationships observed among the snake venom enzymes parallel the phylogenetic classification of the venomous reptiles from which they were derived. It is proposed that phospholipases A/sub 2/ of this general type be divided into two groups depending upon the presence or absence of distinctive structural features elucidated in this study.

  20. Neutron activation analysis of several elements in the unicellular alga Cyanidium caldarium irradiated by. cap alpha. particles from neutron captured boron

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, Shuho; Oota, Tadachika; Otani, Mayumi; Aso, Sueo (Tokyo Univ. of Agriculture (Japan))

    1984-02-01

    The TRIGA MARK 2 atomic reactor was used not only for instrumental neutron activation analysis (INAA) but also as the irradiation source of ..cap alpha.. particles derived from the /sup 10/B(n, ..cap alpha..)/sup 7/Li reaction for biological samples. The acidophilic and thermophilic unicellular alga (Cyanidium caldarium Geitler) was incubated for 20 hours after irradiation and then its elemental concentrations were analysed by INAA. An increase in the quantities of /sup 56/Mn, /sup 28/Al and /sup 38/Cl, and a decrease of /sup 27/Mg and /sup 42/K were detected in the irradiated cells in contrast to non-irradiated cells.

  1. Angular and velocity distributions of secondary particles emitted in interaction of 3. 6-GeV/nucleon. cap alpha. particles and lead nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Antonenko, V.G.; Vinogradov, A.A.; Galitskii, V.M.; Grigor' yan, Y.I.; Ippolitov, M.S.; Karadzhev, K.V.; Kuz' min, E.A.; Man' ko, V.I.; Ogloblin, A.A.; Paramonov, V.V.; Tsvetkov, A.A.

    1980-04-01

    The technique is described and results presented of measurements of the velocity and angular distributions of pions, protons, and deuterons, and tritons emitted in bombardment of lead nuclei by ..cap alpha.. particles with energy 3.6 GeV/nucleon.

  2. A comparison of the in vitro binding of. cap alpha. -tocopherol to microsomes of lung, liver, heart and brain of the rat

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, D.J.; Mavis, R.D.

    1981-01-01

    The in vitro binding of ..cap alpha..-tocopherol to microsomes of lung, liver, heart and brain of the rat was studied with the insoluble tocopherol ligand presented as a complex with bovine serum albumin. Under these conditions, all microsomes showed nonsaturable binding of ..cap alpha..-tocopherol and the amount bound to microsomes was linearly proportional to the concentration of albumin-complexed tocopherol. Increasing the amount of ..cap alpha..-tocopherol bound to microsomes in this manner reduced the extent of lipid peroxidation induced by added ferrous iron. The apparent affinities of the microsomes for ..cap alpha..-tocopherol, as indicated by the amount bound at a given concentration of albumin-complexed tocopherol, decreased in the order brain>liver approximately equal to heart>lung. The differences in affinity did not correlate with total fatty acid content (r=-0.39), total unsaturated fatty acid content (r=-0.26), or with the content of fatty acids containing two or more double bonds (r=-0.01). A high positive correlation was found with the content of fatty acids containing three or more double bonds (r=+0.96). Since lung microsomes contain approximately 6-times the tocopherol levels of liver and brain and about twice that of heart microsomes, these results show that the in vivo levels of microsomal tocopherol do not reflect microsomal affinity for this biological antioxidant.

  3. An easy method for the determination of Ra isotopes and actinide alpha emitters from the same water sample

    International Nuclear Information System (INIS)

    Radium isotopes and actinide α emitters are easily determined from the same water sample. The Ra fraction is obtained by coprecipitation with Ba, while a Fe coprecipitation is used for the actinides. Both fractions are measured with a gas-flow proportional counter. Additionally the isotopic Ra composition is obtained by measuring at two or three different times the α activity from the Ra-fraction. The method is applied to rain water and drinking water samples. (author)

  4. Lyman-Alpha Emitter Galaxies at z ~ 2.8 in the Extended Chandra Deep Field-South: I. Tracing the Large-Scale Structure via Lyman-Alpha Imaging

    CERN Document Server

    Zheng, Zhen-Ya; Rhoads, James E; Finkelstein, Steven L; Wang, Jun-Xian; Jiang, Chun-Yan; Cai, Zheng

    2016-01-01

    We present a narrowband survey with three adjacent filters for z=2.8--2.9 Lyman Alpha Emitter (LAE) galaxies in the Extended Chandra Deep Field South (ECDFS), along with spectroscopic followup. With a complete sample of 96 LAEs in the narrowband NB466, we confirm a large-scale structure at z~ 2.8. Compared to the blank field in NB470 and NB475, the LAE density excess in the NB466 field is ~6.0+/-0.8 times the standard deviation expected at z~2.8, assuming a linear bias of 2. The overdense large scale structure in NB466 can be decomposed into 4 protoclusters, whose overdensities are 4.6 - 6.6. These 4 protoclusters are expected to evolve into a Coma-like cluster at z~ 0. In the meanwhile, we investigate the average star-formation rates derived from Ly{\\alpha}, rest-frame UV and X-ray, the Ly{\\alpha} luminosity functions, the Ly{\\alpha} photon densities and their dependence on the environment. We find that the Ly{\\alpha} photon density in the overdense field (NB466) is ~50\\% higher than that in the blank field ...

  5. The Subaru FMOS Galaxy Redshift Survey (FastSound). I. Overview of the Survey Targeting on H$\\alpha$ Emitters at $z \\sim 1.4$

    CERN Document Server

    Tonegawa, Motonari; Okada, Hiroyuki; Akiyama, Masayuki; Dalton, Gavin; Glazebrook, Karl; Iwamuro, Fumihide; Maihara, Toshinori; Ohta, Kouji; Shimizu, Ikkoh; Takato, Naruhisa; Tamura, Naoyuki; Yabe, Kiyoto; Bunker, Andrew J; Coupon, Jean; Ferreira, Pedro G; Frenk, Carlos S; Goto, Tomotsugu; Hikage, Chiaki; Ishikawa, Takashi; Matsubara, Takahiko; More, Surhud; Okumura, Teppei; Percival, Will J; Spitler, Lee R; Szapudi, Istvan

    2015-01-01

    FastSound is a galaxy redshift survey using the near-infrared Fiber Multi-Object Spectrograph (FMOS) mounted on the Subaru Telescope, targeting H$\\alpha$ emitters at $z \\sim 1.18$--$1.54$ down to the sensitivity limit of H$\\alpha$ flux $\\sim 2 \\times 10^{-16} \\ \\rm erg \\ cm^{-2} s^{-1}$. The primary goal of the survey is to detect redshift space distortions (RSD), to test General Relativity by measuring the growth rate of large scale structure and to constrain modified gravity models for the origin of the accelerated expansion of the universe. The target galaxies were selected based on photometric redshifts and H$\\alpha$ flux estimates calculated by fitting spectral energy distribution (SED) models to the five optical magnitudes of the Canada France Hawaii Telescope Legacy Survey (CFHTLS) Wide catalog. The survey started in March 2012, and all the observations were completed in July 2014. In total, we achieved $121$ pointings of FMOS (each pointing has a $30$ arcmin diameter circular footprint) covering $20.6...

  6. A High Fraction of Ly-alpha-Emitters Among Galaxies with Extreme Emission Line Ratios at z ~ 2

    CERN Document Server

    Erb, Dawn K; Steidel, Charles C; Strom, Allison L; Rudie, Gwen C; Trainor, Ryan F; Shapley, Alice E; Reddy, Naveen A

    2016-01-01

    Star-forming galaxies form a sequence in the [OIII]/H-beta vs. [NII]/H-alpha diagnostic diagram, with low metallicity, highly ionized galaxies falling in the upper left corner. Drawing from a large sample of UV-selected star-forming galaxies at z~2 with rest-frame optical nebular emission line measurements from Keck-MOSFIRE, we select the extreme ~5% of the galaxies lying in this upper left corner, requiring log([NII]/H-alpha) = 0.75. These cuts identify galaxies with 12 + log(O/H) 20 A. We compare the equivalent width distribution of a sample of 522 UV-selected galaxies at 2.0alpha equivalent width -1 (-4) A, and only 9% of these galaxies qualify as LAEs. The extreme galaxies typically have lower attenuation at Ly-alpha than those in the comparison sample, and have ~50% lower median oxygen abundances. Both factors are likely to facilitate the escape of Ly-alpha: in less dusty galaxies Ly-alpha photons are l...

  7. Measurement of the absolute activity of alpha or beta emitters by measuring product nuclei (daughter) activity increase or by studing its radioactive decay

    International Nuclear Information System (INIS)

    A new method for determining absolute activity of alpha or beta emitters by measuring daughter product radioactive decay is presented. The separation method of UX from hexahydrated uranyl nitrate UO2(NO3)2 6H2O based on its dissolution in ethyl ether is described and the accuracy of this method is shown. The factors which accuate on total efficiency of a Geiger Mueller detector for beta particles are determined. The possibility to determine the mass of precursor element by daughter nuclei activity is shown. The results are compared with the one obtained by direct measurement of the mass (or number of atoms) of precursor radioactive substance and with theoretical values calculated for isotopes in secular equilibrium. (Author)

  8. Cyclic AMP regulation of the human glycoprotein hormone. cap alpha. -subunit gene is mediated by an 18-base-pair element

    Energy Technology Data Exchange (ETDEWEB)

    Silver, B.J.; Bokar, J.A.; Virgin, J.B.; Vallen, E.A.; Milsted, A.; Nilson, J.H.

    1987-04-01

    cAMP regulates transcription of the gene encoding the ..cap alpha..-subunit of human chorionic gonadotropin (hCG) in the choriocarcinoma cells (BeWo). To define the sequences required for regulation by cAMP, the authors inserted fragments from the 5' flanking region of the ..cap alpha..-subunit gene into a test vector containing the simian virus 40 early promoter (devoid of its enhancer) linked to the bacterial chloramphenicol acetyltransferase (CAT) gene. Results from transient expression assays in BeWo cells indicated that a 1500-base-pair (bp) fragment conferred cAMP responsiveness on the CAT gene regardless of position or orientation of the insert relative to the viral promoter. A subfragment extending from position -169 to position -100 had the same effect on cAMP-induced expression. Furthermore, the entire stimulatory effect could be achieved with an 18-bp synthetic oligodeoxynucleotide corresponding to a direct repeat between position -146 and -111. In the absence of cAMP, the ..cap alpha..-subunit 5' flanking sequence also enhanced transcription from the simian virus 40 early promoter. They localized this enhancer activity to the same -169/-100 fragment containing the cAMP response element. The 18-bp element alone, however, had no effect on basal expression. Thus, this short DNA sequence serves as a cAMP response element and also functions independently of other promoter-regulatory elements located in the 5' flanking sequence of the ..cap alpha..-subunit gene.

  9. E2 contribution to the /sup 12/C(. cap alpha. ,. gamma. )/sup 16/O reaction at stellar energies in a coupled channel approach

    Energy Technology Data Exchange (ETDEWEB)

    Funck, C.; Langanke, K.; Weiguny, A.

    1985-02-28

    The E2 part of the /sup 12/C(..cap alpha..,..gamma..)/sup 16/O capture process at stellar energies is calculated in a microscopically founded coupled channel approach based on the rotational model of Tamura. At the astrophysically most effective energy we obtain an S-factor for E2 capture of Ssub(E2)(300 keV)=0.10 MeV b.

  10. Chiral effects on the /sup 13/C resonances of. cap alpha. -tocopherol and related compounds. A novel illustration of Newman's rule of six

    Energy Technology Data Exchange (ETDEWEB)

    Brownstein, S.; Burton, G.W.; Hughes, L.; Ingold, K.U.

    1989-02-03

    The 100-MHz /sup 13/C NMR spectrum of (2R,4'R,8'R)-..cap alpha..-tocopherol (natural vitamin E) has been completely assigned with the aid of a number of selectively deuteriated (2R,4'R,8'R)-..cap alpha..-tocopherols. The /sup 13/C NMR spectrum of (2RS,4'RS,8'RS)-..cap alpha..-tocopherol (all-racemic, synthetic vitamin E) has also been measured. Many of the individual carbons in this all-racemic mixture of eight ..cap alpha..-tocopherol stereoisomers give more than one resonance with eight of the carbons (2-CH/sub 3/, 2',3',4',4'-CH/sub 3/, 5', 8', and 9') giving the maximum number of four resonances from each of the four enantiomeric pairs; these resonances have also been assigned. The structurally related 5'-hydroxy-2-(4',8',12'-trimethyltridecyl)-2,4,6,7-tetramethyl-2,3,-dihydrobenzofuran (HTDBF) has been synthesized for the first time in the 2R,4'R,8'R and 2S,4'R,8'R configurations and their /sup 13/C resonances have been assigned. In its all-racemic form this compound also shows up to four resonances from a single carbon. Related observations have been made with phytol and isophytol. A careful examination of these chirally induced chemical shift differences for the individual carbon atoms, ..delta.., reveals a bond-alternation effect with maxima at a separation of one, three, and five bonds from the closest chiral center and with the maximum at a five-bond separation being greater than that at a three-bond separation. 32 references, 2 figures, 4 tables.

  11. cap alpha. -L-iduronidase deficiency in mucopolysaccharidosis type I against a radio-labelled sulfated disaccharide substrate derived from dermatan sulfate

    Energy Technology Data Exchange (ETDEWEB)

    Muller, V.J.; Hopwood, J.J. (Department of Chemical Pathology, The Adelaide Children' s Hospital Inc., North Adelaide, South Australia)

    1984-01-01

    ..cap alpha..-L-Iduronidase activity was assayed by incubation of a radiolabelled disaccharide, O-(..cap alpha..-L-idopyranosyluronic acid)-(1 arrow 3)-2,5 anhydro-D-(1, /sup 3/H)-talitol 4-sulfate (IdoA-anT4S) derived from dermatan sulfate, with homogenates of leucocytes, cultured amniotic cells and skin fibroblasts from normal individuals and patients affected with an ..cap alpha..-L-iduronidase-deficiency disorder (mucopolysaccharidosis type I, MPS I), parents of such patients and patients affected with other mucopolysaccharidoses. The assay clearly distinguished affected homozygotes from normal controls, heterozygotes and other mucopolysaccharidosis types. Preliminary results show that fibroblast homogenates from patients with the MPS I Hurler phenotype were virtually unable to hydrolyse IdoA-anT4S, whereas fibroblast homogenates from a patient with a relatively mild (Scheie) phenotype exhibited a residual activity with Vsub(max) value of 2.5 pmol/min/mg protein and an apparent Ksub(m) of 21 ..mu..mol/l compared to a range of 1020-2105 pmol/min/mg for Vsub(max) and 12-35 ..mu..mol/l for Ksub(m) for fibroblasts from normal controls.

  12. Influence of prostaglandins E/sub 2/ and F/sub 2. cap alpha. / on the zinc transport across rat mid-intestine in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Song, M.K.; Adham, N.F.; Lee, D.B.N.; Carmack, C.R.

    1986-03-05

    Effects of physiological (5.0 ..mu..M) and pharmacological (50 ..mu..M) doses of prostaglandins (PG) E/sub 2/ and F/sub 2..cap alpha../ on the zinc transport rate across rat jejunum mounted on a Ussing Chamber were determined. Zinc transport rate from mucosal to serosal direction was 4.82 +/- 0.81 n moles/hr/cm/sup 2/ whereas the opposite direction was 18.71 +/- 0.96 n moles/hr/cm/sup 2/. When 5.0 ..mu..M or 50 ..mu..M PGE/sub 2/ or PGF/sub 2..cap alpha../ were added into Ringers-Krebs bicarbonate solution containing 3 mM L-histidine and 0.5 mM /sup 65/Zn Cl/sub 2/ to the mucosal side of mucosa, no significant difference in /sup 65/Zn transport rate was observed compared to controls. However, 5.0 ..mu..M PGF/sub 2..cap alpha../ and 50 ..mu..M PGE/sub 2/ significantly inhibited zinc transport from mucosal to serosal direction. When PGs were added to the opposite side of mucosa, only 5.0 ..mu..M PGs significantly inhibited zinc transport from serosal to mucosal direction. Results suggest that PGs act on the inhibition of zinc transport across the basolateral membrane of columnar absorbing cells and that 50 ..mu..M PGE/sub 2/ was the most powerful inhibitor.

  13. Development of high sensitivity spectrometric alpha emitter detector for use in monitoring of environment and radio protection

    International Nuclear Information System (INIS)

    The aim of the project was to design and construct a prototype of a reliable high sensitivity alpha particle detector which will complement solid state track detectors in applications which require superior energy resolution and in which the need for etching is inappropriate. A multiwire proportional chamber of alpha particles was developed that is adaptable for samples deposited onto carriers or introduced in a gaseous form. The final report covers in fact the whole duration of the project with a particular attention to the work done during the last year. (R.P.) 7 refs., 8 figs

  14. Study on the risk of late damage in humans after incorporation of the short-lived alpha emitter Ra-224

    International Nuclear Information System (INIS)

    An epidemiological study has been carried out at the GSF - National Research Center for Environment and Health - between 1948 and 1975, on 1460 ankylosing spondylitis (AS) patients. The aim of the study was to ascertain the late health effects suffered by these patients who had received repeated intravenous injections of the short lived α-emitter 224Ra. These patients have been followed together with a control group of 1323 ankylosing spondylitis patients not treated with radioactive drugs and/or X-rays. Causes of death have been ascertained for 842 exposed patients and 861 controls by the end of 2002. In the exposed group there has been a total of 219 malignant diseases and 206 cases among the controls. In particular, we observed 15 cases of leukaemia in the exposure group and 8 cases of leukaemia in the control group. Further subclassification of the leukaemias demonstrated a high increase of myeloid leukaemia in the exposure group (9 cases obs. vs. 2.5 cases exp.), and out of these especially the acute myeloid leukaemias (6 cases observed vs. 1.6 expected), whereas in the control group the observed cases are within the expected range (3 myeloid leukaemias vs. 2.6 cases). Out of these 6 cases of myeloid leukaemia, 3 cases have been observed at doses comparable to those of the currently applied 224Ra treatment with the preparation SpondylAT registered, in one case the 224Ra-dose was the 0.6fold, in another case 1.6fold, whereas in one case the total dose could not be verified exactly. The enhanced leukaemia incidence in our exposed group is in line with results from animal experiments in mice having been injected with bone seeking α-emitters given at low dose rates. (orig.)

  15. Radiolytic oxidation of UO{sub 2} pellets doped with alpha-emitters ({sup 238/239}Pu)

    Energy Technology Data Exchange (ETDEWEB)

    Muzeau, B. [Commissariat a l' Energie Atomique, Rhone Valley Research Center DTCD/SECM/LMPA, BP 17 171, 30207 Bagnols-sur-Ceze Cedex (France); Jegou, C. [Commissariat a l' Energie Atomique, Rhone Valley Research Center DTCD/SECM/LMPA, BP 17 171, 30207 Bagnols-sur-Ceze Cedex (France)], E-mail: christophe.jegou@cea.fr; Delaunay, F. [Commissariat a l' Energie Atomique, Valduc Research Center, 21120 Is-sur-Tille (France); Broudic, V. [Commissariat a l' Energie Atomique, Rhone Valley Research Center DTCD/SECM/LMPA, BP 17 171, 30207 Bagnols-sur-Ceze Cedex (France); Brevet, A. [Commissariat a l' Energie Atomique, Valduc Research Center, 21120 Is-sur-Tille (France); Catalette, H. [Electricite de France, Les Renardieres Research Center, Route de Sens Ecuelles, 77250 Moret-sur-Loing (France); Simoni, E. [Institut de Physique Nucleaire, Bat. 100, 91406 Orsay Cedex (France); Corbel, C. [Laboratoire des Solides Irradies, UMR 7642-CNRS-CEA-Ecole Polytechnique, Ecole Polytechnique, 91128 Palaiseau Cedex (France)

    2009-01-07

    To assess the impact of alpha radiolysis of water on the oxidative dissolution of UO{sub 2} under anoxic conditions, two series of plutonium-doped samples (specific alpha activity 385 and 18 MBqg{sub UO{sub 2}}{sup -1}) were fabricated, characterized and leached in water of varying complexity (pure water, carbonated water, dissolved hydrogen). Given the very high reactivity of these samples in the presence of air and in order to minimize any prior surface oxidation, a strict experimental protocol was developed based on high-temperature annealing in Ar + 4% H{sub 2} with preleaching cycles. Failure to follow this protocol prevents absolute quantification of oxidation of the UO{sub 2} surface by water radiolysis in solutions. Preoxidation of the pellet surface can lead to uranium release in solution that is dependent on the alpha particle flux, revealing initial oxidation by radiolysis in air including potential traces of water. This makes difficult the accurate quantification of the radiolytic oxidation in water solutions. Controlling the initial surface condition of the samples finally allowed us to demonstrate that radiolytic oxidation in water-saturated media is governed by several threshold effects for which the main parameters are the sample alpha activity and the hydrogen concentration.

  16. Spectral Energy Distribution Fitting of HETDEX Pilot Survey Lyman-alpha Emitters in COSMOS and GOODS-N

    CERN Document Server

    Hagen, Alex; Gronwall, Caryl; Acquaviva, Viviana; Bridge, Joanna; Zeimann, Gregory R; Blanc, Guillermo A; Bond, Nicholas A; Finkelstein, Steven L; Song, Mimi; Gawiser, Eric; Fox, Derek B; Gebhardt, Henry; Malz, A I; Schneider, Donald P; Drory, Niv; Gebhardt, Karl; Hill, Gary J

    2014-01-01

    We use broadband photometry extending from the rest-frame UV to the near-IR to fit the individual spectral energy distributions (SEDs) of 63 bright (L(Ly-alpha) > 10^43 ergs/s) Ly-alpha emitting galaxies (LAEs) in the redshift range 1.9 < z < 3.6. We find that these LAEs are quite heterogeneous, with stellar masses that span over three orders of magnitude, from 7.5 < log M < 10.5. Moreover, although most LAEs have small amounts of extinction, some high-mass objects have stellar reddenings as large as E(B-V) ~0.4. Interestingly, in dusty objects the optical depths for Ly-alpha and the UV continuum are always similar, indicating that Ly-alpha photons are not undergoing many scatters before escaping their galaxy. In contrast, the ratio of optical depths in low-reddening systems can vary widely, illustrating the diverse nature of the systems. Finally, we show that in the star formation rate (SFR)-log mass diagram, our LAEs fall above the "main-sequence" defined by z ~ 3 continuum selected star-forming...

  17. Leaching of UO2 pellets doped with alpha- emitters (Pu-238/239) in synthetic deep Callovian-Oxfordian groundwater

    International Nuclear Information System (INIS)

    The reactivity of a polycrystalline UO2 surface under alpha irradiation in contact with groundwater is investigated, in the hypothesis of direct disposal of spent fuel in a deep geological repository. Two series of plutonium-doped UO2 samples (specific alpha activity of 18 and 385 MBq. g-1 (UO2)) were leached in a synthetic Callovian-Oxfordian deep groundwater under anoxic conditions (Ar/CO2 3000 ppm, 3. 5 bar relative pressure) to assess both the impact of alpha radiolysis of water and the complexing capacity of the groundwater ions on the dissolution of UO2. This study follows a prior one performed in pure and carbonated waters. Firstly, technical developments were necessary for the analyses in the groundwater solution because of its high salt concentrations: quantification limits were determined for the measurement of uranium and radiolytic H2O2 traces in this medium. Secondly, given the very high reactivity of these samples in the presence of air and in order to minimize any prior surface oxidation, a strict experimental protocol was followed, based on high-temperature annealing in Ar + 4% H2 with pre-leaching cycles. Each type of UO2 pellet was then leached under static conditions for 30 days (anoxic conditions, deep groundwater solutions). Results on the evolution of uranium releases are presented. For the lowest alpha activity (18 MBq. g-1(UO2)), uranium releases in groundwater were below the quantification limit of 2 * 10-8 mol. L-1 with a kinetic phosphorescence analyzer, even after 30 days. However, for higher alpha activity (385 MBq. g-1(UO2)) the uranium releases begin to exceed the quantification limit after 14 days of leaching and then increase exponentially. This increase is comparable to results previously obtained in carbonated solutions. (authors)

  18. Quality assurance exercise for estimating radiochemical recovery and low-levels of alpha emitters in urine samples: performance of Health Physics Laboratory, Tarapur

    International Nuclear Information System (INIS)

    As a part of quality assurance, Health Physics Laboratory took part in National inter-comparison exercise organized by Internal Dosimetry Section (IDS), BARC, Trombay for estimating radiochemical recovery of 232U, 242Pu and low-levels of alpha emitter such as 239Pu, 238U and 234U in five urine samples coded D1, D2, D3, D4 and D5. In this paper, performance of Health Physics Laboratory in the inter-comparison exercise is presented. The results submitted by Health Physics laboratory were found to be in good agreement with the organizer's (spiked) values. Nearly 6 laboratories from India participated in this inter-comparison exercise. The samples received, sample pre-concentration, radiochemical separation and alpha activity quantification procedure followed and the results obtained were reported to Head, IDS, BARC, Trombay within stipulated time. The radiochemical analysis of U-isotopes and Pu-isotopes in bioassay samples has been carried out by standardized analytical procedures

  19. Differential gene expression in human fibroblasts after alpha-particle emitter (211)At compared with (60)Co irradiation

    DEFF Research Database (Denmark)

    Danielsson, Anna; Claesson, Kristina; Parris, Toshima Z; Helou, Khalil; Nemes, Szilárd; Elmroth, Kecke; Elgqvist, Jörgen; Jensen, Holger; Hultborn, Ragnar

    2013-01-01

    Purpose: The aim of this study was to identify gene expression profiles distinguishing alpha-particle (211)At and (60)Co irradiation. Materials and methods: Gene expression microarray profiling was performed using total RNA from confluent human fibroblasts 5 hours after exposure to (211)At labeled...... trastuzumab monoclonal antibody (0.25, 0.5, and 1 Gy) and (60)Co (1, 2, and 3 Gy). Results: We report gene expression profiles that distinguish the effect different radiation qualities and absorbed doses have on cellular functions in human fibroblasts. In addition, we identified commonly expressed transcripts...... transcription, cell cycle regulation, and cell cycle arrest, whereas mitosis, spindle assembly checkpoint, and apoptotic chromosome condensation were uniquely enriched for alpha particle irradiation. Conclusions: LET-dependent transcriptional modulations were observed in human fibroblasts 5 hours after...

  20. Spectral Energy Distribution Fitting of Hetdex Pilot Survey Ly-alpha Emitters in Cosmos and Goods-N

    Science.gov (United States)

    Hagen, Alex; Ciardullo, Robin; Cronwall, Caryl; Acquaviva, Viviana; Bridge, Joanna; Zeimann, Gregory R.; Blanc, Guillermo; Bond, Nicholas; Finkelstein, Steven L.; Song, Mimi; Gawiser, Eric; Fox, Derek B.; Gebhardt, Henry; Malz, A. I; Schneider, Donald P.; Drory, Niv; Gebhardt, Karl; Hill, Gary J.

    2014-01-01

    We use broadband photometry extending from the rest-frame UV to the near-IR to fit the individual spectral energy distributions of 63 bright (L(Ly-alpha) greater than 10(exp 43) erg s(exp -1) Ly-alpha emitting galaxies (LAEs) in the redshift range 1.9 less than z less than 3.6. We find that these LAEs are quite heterogeneous, with stellar masses that span over three orders of magnitude, from 7.5 greater than logM/solar mass less than 10.5. Moreover, although most LAEs have small amounts of extinction, some high-mass objects have stellar reddenings as large as E(B - V ) is approximately 0.4. Interestingly, in dusty objects the optical depths for Ly-alpha and the UV continuum are always similar, indicating that Lya photons are not undergoing many scatters before escaping their galaxy. In contrast, the ratio of optical depths in low-reddening systems can vary widely, illustrating the diverse nature of the systems. Finally, we show that in the star-formation-rate-log-mass diagram, our LAEs fall above the "main-sequence" defined by z is approximately 3 continuum selected star-forming galaxies. In this respect, they are similar to submillimeter-selected galaxies, although most LAEs have much lower mass.

  1. The Rest-Frame Optical Spectroscopic Properties of Ly$\\alpha$-Emitters at $z\\sim2.5$: The Physical Origins of Strong Ly$\\alpha$ Emission

    CERN Document Server

    Trainor, Ryan F; Steidel, Charles C; Rudie, Gwen C

    2016-01-01

    We present rest-frame optical spectra of 60 faint ($R_{AB}\\sim 27$; $L\\sim0.1 L_*$) Ly$\\alpha$-selected galaxies (LAEs) at $z\\approx2.56$. The average LAE is consistent with the extreme low-metallicity end of the continuum-selected galaxy distribution at $z\\approx2-3$. In particular, the LAEs have extremely high [OIII] $\\lambda$5008/H$\\beta$ ratios (log([OIII]/H$\\beta$) $\\sim$ 0.8) and low [NII] $\\lambda$6585/H$\\alpha$ ratios (log([NII]/H$\\alpha$) $<-1.15$). Using the [OIII] $\\lambda$4364 auroral line, we find that the star-forming regions in faint LAEs are characterized by high electron temperatures ($T_e\\approx1.8\\times10^4$K), low oxygen abundances (12 + log(O/H) $\\approx$ 8.04, $Z_{neb}\\approx0.22Z_\\odot$), and high excitations with respect to more luminous galaxies. Our faintest LAEs have line ratios consistent with even lower metallicities, including six with 12 + log(O/H) $\\approx$ 6.9$-$7.4 ($Z_{neb}\\approx0.02-0.05Z_\\odot$). We interpret these observations in light of new models of stellar evoluti...

  2. The application of novel methods to determine the concentration and distribution of alpha emitters in environmental materials

    International Nuclear Information System (INIS)

    Practical applications are described for the use of polycarbonate, cellulose nitrate and CR-39 thermoset plastic, as dielectric detectors for recording alpha particle and fission event radioactivity for samples taken from marine environments. For commonly found mixtures of plutonium isotopes, such as 238Pu, 239+240Pu and 241Am, the relative abundance of each type tends to be constant within a defined geographical area, hence the total activity measured with the plastics can be apportioned on the basis of relative abundance information which is usually available from other sources. In studies concerned with the biological uptake and metabolism of uranium, thorium and the transuranides (Np, Pu, Am, Cm, Cf,) dielectric detectors are being used in the vicinity of the Windscale nuclear complex, Cumbria; materials investigated are Mytilus edulis (total animals and organs), various types of seaweed, particulate matter resuspended at the sediment/water interface, deposited sediments and aeolian deposits. Following chemical separation dielectric detectors are used to determine total U, Th, Pu, Am, Cu and Cf; chemical speciation has also been examined following chemical separation of individual valency states of the nuclides by thin layer chromatography, followed by detection of alpha particle activity by exposing sheets of plastics against the chromatograms. When the detectors are used in an autoradiographic mode the distribution of activity in thin and thick samples of biological tissues and sediments can be examined. (author)

  3. Biochemical studies of mouse brain tubulin: colchicine binding (DEAE-cellulose filter) assay and subunits (. cap alpha. and. beta. ) biosynthesis and degradation (in newborn brain)

    Energy Technology Data Exchange (ETDEWEB)

    Tse, Cek-Fyne

    1978-01-01

    A DEAE-cellulose filter assay, measuring (/sup 3/H)colchicine bound to colchicine binding protein (CBP) absorbed on filter discs, has been modified to include lM sucrose in the incubation medium for complexing colchicine to CBP in samples before applying the samples to filter discs (single point assay). Due to the much greater stability of colchicine binding capacity in the presence of lM sucrose, multiple time-point assays and least squares linear regression analysis were not necessary for accurate determination of CBP in hybrid mouse brain at different stages of development. The highest concentrations of CBP were observed in the 160,000g supernatant and pellet of newborn brain homogenate. Further studies of the modified filter assay documented that the assay has an overall counting efficiency of 27.3%, that DEAE-cellulose filters bind and retain all tubulin in the assay samples, and that one molecule of colchicine binds approximately one molecule of tubulin dimer. Therefore, millimoles of colchicine bound per milligram total protein can be used to calculate tubulin content. With this technique tubulin content of brain supernatant was found to be 11.9% for newborn, and 7.15% for 11 month old mice. Quantitative densitometry was also used to measure mouse brain supernatant actin content for these two stages. In vivo synthesis and degradation rates of tubulin ..cap alpha.. and ..beta.. subunits of two day mouse brain 100,000g supernatant were studied after intracerebral injection of (/sup 3/H)leucine. Quantitative changes of the ratio of tritium specific activities of tubulin ..cap alpha.. and ..beta.. subunits with time were determined. The pattern of change was biphasic. During the first phase the ratio decreased; during the second phase the ratio increased continuously. An interpretation consistent with all the data in this study is that the ..cap alpha.. subunit is synthesized at a more rapid rate than the ..beta.. subunit. (ERB)

  4. A GRAVITATIONAL LENS MODEL FOR THE Ly{alpha} EMITTER LAE 221724+001716 AT z = 3.1 IN THE SSA 22 FIELD {sup ,}

    Energy Technology Data Exchange (ETDEWEB)

    Nakahiro, Y.; Kajisawa, M.; Tanaka, A. R.; Hamada, K. [Graduate School of Science and Engineering, Ehime University, Bunkyo-cho 2-5, Matsuyama, Ehime 790-8577 (Japan); Taniguchi, Y.; Shioya, Y.; Kobayashi, M. A. R. [Research Center for Space and Cosmic Evolution, Ehime University, Bunkyo-cho 2-5, Matsuyama, Ehime 790-8577 (Japan); Inoue, A. K. [College of General Education, Osaka Sangyo University, 3-1-1 Nakagaito, Daito, Osaka 574-8530 (Japan); Iwata, I. [Subaru Telescope, National Astronomical Observatory of Japan, 650 North A' ohoku Place, Hilo, HI 96720 (United States); Matsuda, Y. [ALMA Office, National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Hayashino, T. [Research Center for Neutrino Science, Graduate School of Science, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578 (Japan)

    2013-04-01

    During the course of our Lyman continuum imaging survey, we found that the spectroscopically confirmed Ly{alpha} emitter LAE 221724+001716 at z = 3.10 in the SSA 22 field shows strong Lyman continuum emission ({lambda}{sub rest} {approx} 900 A) that escapes from this galaxy. However, another recent spectroscopic survey revealed that the supposed Lyman continuum emission could arise from a foreground galaxy at z = 1.76 if the emission line newly detected from the galaxy at {lambda}{sub obs} Almost-Equal-To 3360 A is Ly{alpha}. If this is the case, as the angular separation between these two galaxies is very small ( Almost-Equal-To 0.''6), LAE 221724+001716 at z = 3.10 could be amplified by the gravitational lensing caused by this intervening galaxy. Here we present a possible gravitational lens model for the system of LAE 221724+001716. First, we estimate the stellar mass of the intervening galaxy as M{sub *} {approx} 3.5 Multiplication-Sign 10{sup 9} M{sub Sun} from its UV luminosity and {approx}3.0 Multiplication-Sign 10{sup 7}-2.4 Multiplication-Sign 10{sup 9} M{sub Sun} through the spectral energy distribution fitting. Then, we find that the gravitational magnification factor ranges from 1.01 to 1.16 using the so-called singular isothermal sphere model for strong lensing. While LAE 221724+001716 is the first system of an LAE-LAE lensing reported so far, the estimated magnification factor is not so significant because the stellar mass of the intervening galaxy is small.

  5. Collective relaxation, single particle motion and short range order in. cap alpha. '-NbD/sub x/: A quasielastic neutron scattering study

    Energy Technology Data Exchange (ETDEWEB)

    Hempelmann, R.; Richter, D.; Faux, D.A.; Ross, D.K.

    1988-01-01

    Applying both incoherent and coherent quasielastic neutron scattering we have studied simultaneously single particle motion, collective relaxation and short range order of deuterium in ..cap alpha..'-NbD/sub x/. A comparison with recent Monte Carlo simulations lead to a consistent description of all results in terms of strongly repulsive deuterium-deuterium interactions. Relating the independently determined tracer and chemical diffusion coefficients with the also measured structure factor we show experimentally that for lattice gases the de Gennes narrowing Ansatz needs to be modified by correlation factors. 18 refs., 3 figs., 1 tab.

  6. No evidence for Population III stars or a Direct Collapse Black Hole in the z = 6.6 Lyman-$\\alpha$ emitter 'CR7'

    CERN Document Server

    Bowler, R A A; Dunlop, J S; McLeod, D J; Stanway, E R; Eldridge, J J; Jarvis, M J

    2016-01-01

    The z = 6.6 Lyman-$\\alpha$ emitter 'CR7' has been claimed to have a Population III-like stellar population, or alternatively, be a candidate Direct Collapse Black Hole (DCBH). In this paper we investigate the evidence for these exotic scenarios using recently available, deeper, optical, near-infrared and mid-infrared imaging. We find strong Spitzer/IRAC detections for the main component of CR7 at 3.6 and 4.5 microns, and show that it has a blue colour ([3.6] - [4.5] $= -1.2\\pm 0.3$). This colour cannot be reproduced by current Pop. III or pristine DCBH models. Instead, the results suggest that the [3.6] band is contaminated by the [OIII]4959,5007 emission line with an implied rest-frame equivalent width of EW_0 (H$\\beta$ + [OIII]) $\\gtrsim 2000$\\AA. Furthermore, we find that new near-infrared data from the UltraVISTA survey supports a weaker He II 1640 emission line than previously measured, with EW_0 $= 40 \\pm 30$\\AA. For the fainter components of CR7 visible in Hubble Space Telescope imaging, we find no evi...

  7. The First Systematic Survey for Lyman Alpha Emitters at z=7.3 with Red-sensitive Subaru/Suprime-Cam

    CERN Document Server

    Shibuya, Takatoshi; Ota, Kazuaki; Iye, Masanori; Ouchi, Masami; Furusawa, Hisanori; Shimasaku, Kazuhiro; Hattori, Takashi

    2011-01-01

    We have performed deep imaging surveys for Lyman Alpha emitters (LAEs) at redshift ~ 7.3 in two blank fields, the Subaru Deep Field (SDF) and the Subaru/XMM-Newton Deep Field (SXDF), using the Subaru/Suprime-Cam equipped with new red-sensitive CCDs and a new narrow-band filter, NB1006 (lambda_c=10,052A, FWHM=214A). By comparing the NB1006 magnitudes of detected objects with those at other shorter wavelength bands, we identified four objects as LAE candidates that exhibit luminosity excess in NB1006. By carrying out deep follow-up spectroscopy for three of them using Subaru/FOCAS and Keck/DEIMOS, a definitively asymmetric emission line is detected for one of them, SXDF-NB1006-2. Assuming this line is LyA, this object is a LAE at z=7.215 which has luminosity of 1.2^{+1.5}_{-0.6} x 10^{43} erg s-1, star formation rate (SFR) of 11 Mo yr-1 estimated from the LyA emission line, and a weighted skewness S_w = 4.90+-0.86. Another object, SDF-NB1006-2, shows variable photometry and is thus probably a quasar (QSO) or an...

  8. Kiloparsec Mass/Light Offsets in the Galaxy Pair-Lyman-alpha Emitter Lens System SDSS\\,J1011$+$0143

    CERN Document Server

    Shu, Yiping; Moustakas, Leonidas A; Stern, Daniel; Dey, Arjun; Brownstein, Joel R; Burles, Scott; Spinrad, Hyron

    2016-01-01

    We report the discovery of significant mass/light offsets in the strong gravitational lensing system SDSS\\,J1011$+$0143. We use the high-resolution \\textsl{Hubble Space Telescope} (\\textsl{HST}) F555W- and F814W-band imaging and SDSS spectroscopy of this system, which consists of a close galaxy pair with a projected separation of $\\approx 4.2$ kpc at $z_{\\rm lens} \\sim 0.331$ lensing a Lyman-alpha emitter (LAE) at $z_{\\rm source} = 2.701$. Comparisons between the mass peaks inferred from lens models and light peaks from \\textsl{HST} imaging data reveal significant spatial mass/light offsets as large as $(1.72 \\pm 0.24 \\pm 0.34)$ kpc in both filter bands. Such large mass/light offsets, not seen in isolated field lens galaxies and relaxed galaxy groups, may be related to the interactions between the two lens galaxies. The detected mass/light offsets can potentially serve as an important test for the self-interacting dark matter model. However, other mechanisms such as dynamical friction on spatially differently...

  9. A hard ionizing spectrum in z=3-4 Ly-alpha emitters with intense [OIII] emission: Analogs of galaxies in the reionization era?

    CERN Document Server

    Nakajima, Kimihiko; Iwata, Ikuru; Inoue, Akio; Kusakabe, Haruka; Ouchi, Masami; Robertson, Brant

    2016-01-01

    We present Keck/MOSFIRE spectra of the diagnostic nebular emission lines [OIII]5007,4959, [OII]3727, and H-beta for a sample of 15 redshift z=3.1-3.7 Ly-alpha emitters (LAEs) and Lyman break galaxies (LBGs). In conjunction with spectra from other surveys, we confirm earlier indications that LAEs have a much higher [OIII]/[OII] line ratio than is seen in similar redshift LBGs. By comparing their distributions on a [OIII]/[OII] versus R23 diagram, we demonstrate that this difference cannot arise solely because of their lower metallicities but most likely is due to a harder ionizing spectrum. Using measures of H-beta and recombination theory, we demonstrate, for a subset of our LAEs, that xi_ion - the number of Lyman continuum photons per UV luminosity - is indeed 0.2-0.5 dex larger than for typical LBGs at similar redshifts. Using photoionization models we estimate the effect this would have on both [OIII]/[OII] and R23 and conclude such a hard spectrum can only partially explain such intense line emission. The...

  10. /sup 45/Ca efflux for myometrial cells: comparison of the effects of prostaglandin F/sub 2/. cap alpha. (PGF/sub 2/), oxytocin (OT) and arachidonate (A)

    Energy Technology Data Exchange (ETDEWEB)

    Katona, G.; Molnar, M.; Toth, M.; Hertelendy, F.

    1986-03-01

    The aim of this study was to measure PGF/sub 2..cap alpha../-induced Ca/sup 2 +/ release from uterine cells and to compare this to the actions of OT and A. Smooth muscle cells isolated from the uterus (shell gland) of laying hens were cultured for 7 days in M199 plus 10% fetal calf serum. The cells were treated with digitonin (20..mu..M) and preloaded with /sup 45/Ca for 40 min. Addition of PGF/sub 2..cap alpha../ caused a biphasic /sup 45/Ca-efflux. There was a small but significant /sup 45/Ca-release within 30 sec (rapid phase) followed by a larger one within 7 min (slow phase). In comparison, both OT and A stimulated /sup 45/Ca efflux during a single, slow phase. The maximal effect of A was observed at < 7 min, whereas that of OT was slower, peaking after 7 min. Mepacrin, an inhibitor of A release, attenuated the action of OT without having any effect on A promoted /sup 45/Ca-efflux. Indomethacin, an inhibitor of PG synthase, failed to suppress the Ca-releasing effect of A suggesting the A itself or a lipoxygenase product may have been responsible for the observed effects. Moreover, these results provide suggestive evidence that A release is an important step in the action of various uterotonic agents converging on the mobilization of intracellular Ca.

  11. [OIII] emission line as a tracer of star-forming galaxies at high redshifts: Comparison between H$\\alpha$ and [OIII] emitters at $z$=2.23 in HiZELS

    CERN Document Server

    Suzuki, T L; Sobral, D; Khostovan, A A; Hayashi, M; Shimakawa, R; Koyama, Y; Tadaki, K -i; Tanaka, I; Minowa, Y; Yamamoto, M; Smail, I; Best, P N

    2016-01-01

    We investigate the properties of $z$=2.23 H$\\alpha$ and [OIII]$\\lambda$5007 emitters using the narrow-band-selected samples obtained from the High-$z$ Emission Line Survey (HiZELS: Sobral et al. 2013). We construct two samples of the H$\\alpha$ and [OIII] emitters and compare their integrated physical properties. We find that the distribution of stellar masses, dust extinction, star formation rates (SFRs), and specific SFRs, is not statistically different between the two samples. When we separate the full galaxy sample into three subsamples according to the detections of the H$\\alpha$ and/or [OIII] emission lines, most of the sources detected with both H$\\alpha$ and [OIII] show ${\\rm log(sSFR_{UV})}$$\\gtrsim$-9.5. The comparison of the three subsamples suggests that sources with strong [OIII] line emission tend to have the highest star-forming activity out all galaxies that we study. We argue that the [OIII] emission line can be used as a tracer of star-forming galaxies at high redshift, and that it is especia...

  12. Study on the risk of late damage in humans after incorporation of the short-lived alpha emitter Ra-224; Studie zum Risiko von Spaetschaeden beim Menschen nach Inkorporation des kurzlebigen {alpha}-Strahlers Radium-224

    Energy Technology Data Exchange (ETDEWEB)

    Wick, R.R.; Nekolla, E.A.; Kellerer, A.M. [Muenchen Univ. (Germany). Strahlenbiologisches Inst.; Goessner, W. [Gesellschaft fuer Strahlen- und Umweltforschung mbH Muenchen, Neuherberg (Germany). Inst. fuer Pathologie

    2003-07-01

    An epidemiological study has been carried out at the GSF - National Research Center for Environment and Health - between 1948 and 1975, on 1460 ankylosing spondylitis (AS) patients. The aim of the study was to ascertain the late health effects suffered by these patients who had received repeated intravenous injections of the short lived {alpha}-emitter {sup 224}Ra. These patients have been followed together with a control group of 1323 ankylosing spondylitis patients not treated with radioactive drugs and/or X-rays. Causes of death have been ascertained for 842 exposed patients and 861 controls by the end of 2002. In the exposed group there has been a total of 219 malignant diseases and 206 cases among the controls. In particular, we observed 15 cases of leukaemia in the exposure group and 8 cases of leukaemia in the control group. Further subclassification of the leukaemias demonstrated a high increase of myeloid leukaemia in the exposure group (9 cases obs. vs. 2.5 cases exp.), and out of these especially the acute myeloid leukaemias (6 cases observed vs. 1.6 expected), whereas in the control group the observed cases are within the expected range (3 myeloid leukaemias vs. 2.6 cases). Out of these 6 cases of myeloid leukaemia, 3 cases have been observed at doses comparable to those of the currently applied {sup 224}Ra treatment with the preparation SpondylAT {sup registered}, in one case the {sup 224}Ra-dose was the 0.6fold, in another case 1.6fold, whereas in one case the total dose could not be verified exactly. The enhanced leukaemia incidence in our exposed group is in line with results from animal experiments in mice having been injected with bone seeking {alpha}-emitters given at low dose rates. (orig.) [German] Im Rahmen einer epidemiologischen Studie werden im GSF-Forschungszentrum 1460 Bechterew-Patienten beobachtet, die in den Jahren 1948 bis 1975 zur Behandlung ihrer Krankheit wiederholte intravenoese Injektionen von {sup 224}Ra erhalten haben. Daneben

  13. Extractive separation of micro amounts of rhenium from molybdenite by quinoline and a modified method of rhenium determination by. cap alpha. -furyl-dioxime

    Energy Technology Data Exchange (ETDEWEB)

    Dorz, D.; Dobrowolski, J. (Politechnika Gdanska (Poland))

    1979-01-01

    The extractive separation of rhenium(7) by quinoline in alkaline solution as well as a modification of the spectrophotometric method for the determination of micro amounts of rhenium in a molybdenite from copper-molybdenum ores from Mongolia, using ..cap alpha..-furyldioxime has been developed. On the basis of the extractive separation method of perrhenate ion by quinoline from alkaline solution, rhenium has been determined in molybdenite. The molybdenite was decomposed by four different methods. Two of these decomposition methods, the fusion of Na/sub 2/O/sub 2/ with NaOH and the sintering of CaO with KMnO/sub 4/ were found as the best ones.

  14. Influence of preliminary chronic irradiation and treatment with. cap alpha. -tocopherol on the frequency of chromosome aberrations in mouse bone marrow cells induced by acute. gamma. -irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Aliev, A.A.; Akhundov, V.Yu.; Alekperov, U.K.; Gamzaeva, I.A.; Asadova, A.I.; Shekhtman, A.B.; Gabaj, N.S. (AN Azerbajdzhanskoj SSR, Baku. Inst. Botaniki)

    The incidence of chromosome aberrations in bone marrow cells of femur did not exceed the spontaneous one in CBA mice exposed, during 70 days, to ..gamma..-radiation at dose-rates of 33.7-35.8 nA/kg and cumulative dose of 2.75 Gy. A single acute exposure of intact animals to a dose of 2.98 Gy increased significantly the mutation level. Preirradiation with small doses increased the resistance of hereditary structures to sublethal radiation doses. Exogenous ..cap alpha..-tocopherol (0.06 mg/20 g mass) protected the genetic apparatus of cells from total-body irradiation and was an additional factor decreasing the mutaton level after acute exposure of mice at the background of long-term irradiation with small doses.

  15. Role of a guanine nucleotide-binding protein in. cap alpha. /sub 1/-adrenergic receptor-mediated Ca/sup 2 +/ mobilization in DDT/sub 1/ MF-2 cells

    Energy Technology Data Exchange (ETDEWEB)

    Cornett, L.E.; Norris, J.S.

    1987-11-01

    In this study the mechanisms involved in ..cap alpha../sub 1/-adrenergic receptor-mediated Ca/sup 2 +/ mobilization at the level of the plasma membrane were investigated. Stimulation of /sup 45/Ca/sup 2 +/ efflux from saponin-permeabilized DDT/sub 1/ MF-2 cells was observed with the addition of either the ..cap alpha../sub 1/-adrenergic agonist phenylephrine and guanosine-5'-triphosphate or the nonhydrolyzable guanine nucleotide guanylyl-imidodiphosphate. In the presence of (/sup 32/P) NAD, pertussis toxin was found to catalyze ADP-ribosylation of a M/sub r/ = 40,500 (n = 8) peptide in membranes prepared from DDT/sub 1/, MF-2 cells, possibly the ..cap alpha..-subunit of N/sub i/. However, stimulation of unidirectional /sup 45/Ca/sup 2 +/ efflux by phenylephrine was not affected by previous treatment of cells with 100 ng/ml pertussis toxin. These data suggest that the putative guanine nucleotide-binding protein which couples the ..cap alpha../sub 1/-adrenergic receptor to Ca/sup 2 +/ mobilization in DDT/sub 1/ MF-2 cells is not a pertussis toxin substrate and may possibly be an additional member of guanine nucleotide binding protein family.

  16. Selective alpha particle decay of /sup 12/C + /sup 12/C resonances to excited /sup 20/Ne rotational bands observed in the /sup 12/C(/sup 12/C,. cap alpha. ) /sup 20/Ne reaction

    Energy Technology Data Exchange (ETDEWEB)

    Ledoux, R.J.; Ordonez, C.E.; Bechara, M.J.; Al-Juwair, H.A.; Lavelle, G.; Cosman, E.R.

    1984-09-01

    Excitation functions of the /sup 12/C(/sup 12/C, ..cap alpha..)/sup 20/Ne reaction were measured at Theta/sub lab/ = 7.5/sup 0/ between E/sub c.m./ = 14-40 MeV and angular distributions were measured from E/sub c.m./ = 17.8 to 20.6 MeV. Summed yields reveal prominent intermediate structure resonances over the entire range which correlate well to resonances previously observed in elastic data. The resonances show enhanced decays to excited rotational bands in /sup 20/Ne with reduced widths comparable to those for the elastic channel and an order of magnitude greater than those for the /sup 20/Ne ground state band. A discussion is given of the resonances as shape-isomeric states in a shell model secondary minimum in /sup 24/Mg, and of the selective alpha decay as being transitions to states of related configuration in /sup 20/Ne.

  17. Selective alpha particle decay of /sup 12/C+ /sup 12/C resonances to excited /sup 20/Ne rotational bands observed in the /sup 12/C(/sup 12/C,. cap alpha. ) /sup 20/Ne reaction

    Energy Technology Data Exchange (ETDEWEB)

    Ledoux, R.J.; Ordoez, C.E.; Bechara, M.J.; Al-Juwair, H.A.; Lavelle, G.; Cosman, E.R.

    1984-09-01

    Excitation functions of the /sup 12/C(/sup 12/C,..cap alpha..) /sup 20/Ne reaction were measured at theta/sub lab/ = 7.5/sup 0/ between E/sub c.m./ = 14--40 MeV and angular distributions were measured from E/sub c.m./ = 17.8 to 20.6 MeV. Summed yields reveal prominent intermediate structure resonances over the entire range which correlate well to resonances previously observed in elastic data. The resonances show enhanced decays to excited rotational bands in /sup 20/Ne with reduced widths comparable to those for the elastic channel and an order of magnitude greater than those for the /sup 20/Ne ground state band. A discussion is given of the resonances as shape-isomeric states in a shell model secondary minimum in /sup 24/Mg, and of the selective alpha decay as being transitions to states of related configuration in /sup 20/Ne.

  18. A remarkably high fraction of strong Ly_alpha emitters amongst luminous redshift 6.0

    CERN Document Server

    Curtis-Lake, E; Pearce, H J; Dunlop, J S; Cirasuolo, M; Stark, D P; Almaini, O; Bradshaw, E J; Chuter, R; Foucaud, S; Hartley, W G

    2011-01-01

    We present spectroscopic confirmation of ten highly luminous (L >= 2L*) Lyman alpha emitters in the redshift range 6.01= 6 Lyman break galaxies (LBGs) selected from an area of 0.25 square degrees within the UKIDSS Ultra-deep Survey (UDS). Overall, our high rate of spectroscopic confirmation (>= 71%) and low rate of contamination provides a strong vindication of the photometric redshift analysis used to define the original sample. By considering star-formation rate estimates based on the Ly_alpha and UV continuum luminosity we conclude that our sample is consistent with a Ly_alpha escape fraction of ~25%. Moreover, after careful consideration of the potential uncertainties and biases, we find that 40%-50% of our sample of L >= 2L* galaxies at 6.0= 25 Angs), a fraction which is a factor of ~2 higher than previously reported for L =2 L*) LBGs shows a similarly sharp increase to that observed in their lower-luminosity (L <= L*) counterparts.

  19. Effect of. cap alpha. -tocopherol, butylated-hydroxytoluene and hydroxy-anisole on the activation and binding of aflatoxin B/sub 1/ to macromolecules

    Energy Technology Data Exchange (ETDEWEB)

    Ch' ih, J.J.; Biedrzycka, D.; Devlin, T.M.

    1987-05-01

    The anti-oxidants, ..cap alpha..-tocopherol(TPA), butylated-hydroxy-toluene(BHT) and hydroxyanisole(BHA) inhibit the carcinogenic and toxic effects of a variety of chemical compounds, their effect on aflatoxin B/sub 1/ (AFB/sub 1/) activation and binding was examined utilizing rat liver microsomes and cells. With a NADPH generating system, oxygen, microsomes, (/sup 3/H)-AFB/sub 1/, 2.2 pmoles/h/mg protein was activated and bound to macromolecules. In hepatocytes, 3.4 and 1.4 pmoles of AFB/sub 1/ per 10/sup 6/ cells were taken up and bound to macromolecules, whereas the nucleic acid fraction contained 0.19 pmoles of bound AFB/sub 1/. Moderate decreases of AFB/sub 1/ activation and binding were observed when TPA was present in both cell-free and hepatocytes systems. Only in hepatocytes, BHT inhibited the AFB/sub 1/ uptake and binding to nucleic acids. BHA, however, inhibited microsomal activation of AFB/sub 1/ by 73%; maximum inhibition was reached at 1 mM. AFB/sub 1/ uptake, and binding to nucleic acids were inhibited by 65% and 79% by BHA. GSH-transferase activity of cells treated with these agents was not altered. The effect of BHA at various concentrations on AFB activation was compared with cytochrome P-450 inhibitors; the ED/sub 50/ of SKF 525A, BHA and metyrapone was 9 uM, 80 uM and 380 uM respectively. The data suggest that TPA, BHA and BHT exert their effect by different mechanisms.

  20. Avian serum. cap alpha. /sub 1/-glycoprotein, hemopexin, differing significantly in both amino acid and carbohydrate composition from mammalian (. beta. -glycoprotein) counter parts

    Energy Technology Data Exchange (ETDEWEB)

    Goldfarb, V.; Trimble, R.B.; Falco, M.D.; Liem, H.H.; Metcalfe, S.A.; Wellner, D.; Muller-Eberhard, U.

    1986-10-21

    The physicochemical characteristics of chicken hemopexin, which can be isolated by heme-agarose affinity chromatography, is compared with representative mammalian hemopexins of rat, rabbit, and human. The avian polypeptide chain appears to be slightly longer (52 kDa) than the human, rat, or rabbit forms (49 kDa), and also the glycoprotein differs from the mammalian hemopexins in being an ..cap alpha../sub 1/-glycoprotein instead of a ..beta../sub 1/-glycoprotein. The distinct electrophoretic mobility probably arises from significant differences in the amino acid composition of the chicken form, which, although lower in serine and particularly in lysine, has a much higher glutamine/glutamate and agrinine content, and also a higher proline, glycine, and histidine content, than the mammalian hemopexins. Compositional analyses and /sup 125/I concanavalin A and /sup 125/I wheat germ agglutinin binding suggest that chicken hemopexin has a mixture of three fucose-free N-linked bi- and triantennary oligosaccharides. In contrast, human hemopexin has give N-linked oligosaccharides and an additional O-linked glycan blocking the N-terminal threonine residue, while the rabbit form has four N-linked oligosaccharides. In keeping with the finding of a simpler carbohydrate structure, the avian hemopexin shows only a single band on polyacrylamide gel electrophoresis under both nondenaturing and denaturing conditions, whereas the hemopexins of the three mammalian species tested show several bands. In contrast, the isoelectric focusing pattern of chicken hemopexin is very complex, revealing at least nine bands between pH 4.0 and pH band 5.0, while the other hemopexins show a broad smear of multiple ill-defined bands in the same region.Results indicate the hemopexin of avians differs substantially from the hemopexins of mammals, which show a notable similarity with regard to carbohydrate structure and amino acid composition.

  1. The VIMOS Ultra-Deep Survey (VUDS): fast increase of the fraction of strong Lyman alpha emitters from z=2 to z=6

    CERN Document Server

    Cassata, P; Fevre, O Le; Lemaux, B; Garilli, B; Brun, V Le; Maccagni, D; Pentericci, L; Thomas, R; Vanzella, E; Zamorani, G; Zucca, E; Amorin, R; Bardelli, S; Capak, P; Cassara', L; Castellano, M; Cimatti, A; Cuby, J G; Cucciati, O; de la Torre, S; Durkalec, A; Fontana, A; Giavalisco, M; Grazian, A; Hathi, N P; Ilbert, O; Moreau, C; Paltani, S; Ribeiro, B; Salvato, M; Schaerer, D; Scodeggio, M; Sommariva, V; Talia, M; Taniguchi, Y; Tresse, L; Vergani, D; Wang, P W; Charlot, S; Contini, T; Fotopoulou, S; Lopez-Sanjuan, C; Mellier, Y; Scoville, N

    2014-01-01

    Aims. The aim of this work is to constrain the evolution of the fraction of Lya emitters among UV selected star forming galaxies at 2 25A to increase from 5% at z=2 to 30% at z=6, with the increase being relatively stronger beyond z=4. We observe no difference, for the narrow range of UV luminosities explored in this work, between the fraction of strong Lya emitters among galaxies fainter or brighter than M*, although the fraction for the FUV faint galaxies evolves faster, at 2

  2. Study of alpha-emitters produced in nuclear reactions induced by 12C a 86 MeV/n on medium and heavy targets

    International Nuclear Information System (INIS)

    The work reported in this research thesis is a result from the very first experiments performed on the new Carbon 12 beam proposed by the CERN synchrotron (20 MeV< E/A<100 MeV). By means of an electrostatic collecting system developed within the laboratory, associated with an α detection device, the author measured the productions, energies, recoil distributions and angular distributions of α emitters produced in nuclear reactions induced by Carbon 12 at 1032 MeV, i.e. 86 MeV/n, on heavy targets ranging from Gadolinium to Uranium. These data and the comparison with results obtained by means of an intra-nuclear cascade model allow the main characteristics of these reactions to be identified. These characteristics will be very interesting for the understanding of phenomena occurring at these energy levels, and for the elaboration of a theoretical model describing the evolution of nuclear reactions

  3. Leaching of UO2 pellets doped with alpha-emitters (238/239Pu) in synthetic deep Callovian-Oxfordian groundwater

    International Nuclear Information System (INIS)

    The reactivity of a polycrystalline UO2 surface under alpha irradiation in contact with groundwater is investigated, in the hypothesis of direct disposal of spent fuel in a deep geological repository. Two series of plutonium-doped UO2 samples (specific alpha activity of 18 and 385 MBq·g-1UO2) were leached in a synthetic Callovian-Oxfordian deep groundwater under anoxic conditions (Ar/CO2 3000 ppm, 3.5 bar relative pressure) to assess both the impact of alpha radiolysis of water and the complexing capacity of the groundwater ions on the dissolution of UO2. This study follows a prior one performed in pure and carbonated waters. Firstly, technical developments were necessary for the analyses in the groundwater solution because of its high salt concentrations: quantification limits were determined for the measurement of uranium and radiolytic H2O2 traces in this medium. Secondly, given the very high reactivity of these samples in the presence of air and in order to minimize any prior surface oxidation, a strict experimental protocol was followed, based on high-temperature annealing in Ar + 4% H2 with preleaching cycles. Each type of UO2 pellet was then leached under static conditions for 30 days (anoxic conditions, deep groundwater solutions). Results on the evolution of uranium releases are presented. For the lowest alpha activity (18 MBq·g-1UO2), uranium releases in groundwater were below the quantification limit of 2 x 10-8 mol·L-1 with a kinetic phosphorescence analyzer, even after 30 days. However, for higher alpha activity (385 MBq·g-1UO2) the uranium releases begin to exceed the quantification limit after 14 days of leaching and then increase exponentially. This increase is comparable to results previously obtained in carbonated solutions.

  4. Leaching of UO2 pellets doped with alpha-emitters (238/239Pu) in synthetic deep Callovian-Oxfordian groundwater

    Science.gov (United States)

    Tribet, M.; Jégou, C.; Broudic, V.; Marques, C.; Rigaux, P.; Gavazzi, A.

    2010-03-01

    The reactivity of a polycrystalline UO2 surface under alpha irradiation in contact with groundwater is investigated, in the hypothesis of direct disposal of spent fuel in a deep geological repository. Two series of plutonium-doped UO2 samples (specific alpha activity of 18 and 385 MBq·g-1UO2) were leached in a synthetic Callovian-Oxfordian deep groundwater under anoxic conditions (Ar/CO2 3000 ppm, 3.5 bar relative pressure) to assess both the impact of alpha radiolysis of water and the complexing capacity of the groundwater ions on the dissolution of UO2. This study follows a prior one performed in pure and carbonated waters. Firstly, technical developments were necessary for the analyses in the groundwater solution because of its high salt concentrations: quantification limits were determined for the measurement of uranium and radiolytic H2O2 traces in this medium. Secondly, given the very high reactivity of these samples in the presence of air and in order to minimize any prior surface oxidation, a strict experimental protocol was followed, based on high-temperature annealing in Ar + 4% H2 with preleaching cycles. Each type of UO2 pellet was then leached under static conditions for 30 days (anoxic conditions, deep groundwater solutions). Results on the evolution of uranium releases are presented. For the lowest alpha activity (18 MBq·g-1UO2), uranium releases in groundwater were below the quantification limit of 2 × 10-8 mol·L-1 with a kinetic phosphorescence analyzer, even after 30 days. However, for higher alpha activity (385 MBq·g-1UO2) the uranium releases begin to exceed the quantification limit after 14 days of leaching and then increase exponentially. This increase is comparable to results previously obtained in carbonated solutions.

  5. MUSE integral-field spectroscopy towards the Frontier Fields cluster Abell S1063: II. Properties of low luminosity Lyman alpha emitters at z>3

    CERN Document Server

    Karman, W; Caminha, G B; Gronke, M; Grillo, C; Balestra, I; Rosati, P; Vanzella, E; Coe, D; Dijkstra, M; Koekemoer, A M; Mercurio, A; Nonino, M

    2016-01-01

    In spite of their conjectured importance for the Epoch of Reionization, the properties of low-mass galaxies are currently still under large debate. In this article, we study the stellar and gaseous properties of faint, low-mass galaxies at z>3. We observed the Frontier Fields cluster Abell S1063 with MUSE over a 2 arcmin^2 field, and combined integral-field spectroscopy with gravitational lensing to perform a blind search for intrinsically faint Lya emitters (LAEs). We found in total 14 lensed LAEs and increased the number of spectroscopically-confirmed multiple-image families from 6 to 17, and updated our gravitational-lensing model accordingly. The lensing-corrected Lya luminosities are with L(Lya) =3 are reported. We performed SED modelling to broadband photometry from the {\\em U}-band through the infrared to determine the stellar properties of these LAEs. The stellar masses are very low (10^{6-8} Msun), and are accompanied by very young ages of 1-100 Myr. The very high specific star formation rates (~100/...

  6. Novel method to assessing and the impact of alpha emitter's concentration of the uterus on women fertility in Iraqi Kurdistan region

    International Nuclear Information System (INIS)

    In the present work, 30 uterine tissue samples were collected from women with uterine problems from Iraqi Kurdistan. Tissue samples were analyzed and examined to measure levels of concentrated α-particle emitters and their short-lived decay products using a plastic track detector (CR-39) and the PVC long-tube technique with standard source radium (226Ra). A new method and apparatus for the passive sampling of α-particles were also introduced. The maximum 0.0691 ppm and minimum 0.0180 ppm concentrations of particles were found in Sedakan and in Dukan, respectively; the average value was 0.0330 ppm, when compared the result with the result (0.12 ppm) in Asumadu-Sakyi et al. (Res J Environ Earth Sci 3(1):24-31, 2011) is lower than it and is agree with the result in Rubyie (Radioactive detection on the blood samples of cancer patients diseases by using CR-39 detector and its effect on cytogenetic. MSc. thesis, Al-Nahrain University, 2007). Also the results of fresh uterus are Significant (p 222Rn gas varied from one woman to another depending on her age, the allergic reaction of her uterus to the radiation, and the geological formation of the area under study. The hazardous effects of α-particles are caused by increasing levels of ionizing radiation in the environment. (author)

  7. A New Population of High-z, Dusty Lyman-alpha Emitters and Blobs Discovered by WISE: Feedback Caught in the Act?

    Science.gov (United States)

    Bridge, Carrie R.; Blain, Andrew; Borys, Colin J. K.; Petty, Sara; Benford, Dominic; Eisenhardt, Peter; Farrah, Duncan; Griffith, Roger, L.; Jarrett, Tom; Lonsdale, Carol; Stanford. Spencer A.; Stern, Daniel; Tsai, Chao-Wei; Wright, Edward L.; Wu, Jingwen

    2013-01-01

    By combining data from the NASA Wide-field Infrared Survey Explorer (WISE) mission with optical spectroscopy from the W. M. Keck telescope, we discover a mid-IR color criterion that yields a 78% success rate in identifying rare, typically radio-quiet, 1.6 approx. 10(exp 13)-10(exp 14) Solar L) and have warm colors. They are typically more luminous and warmer than other dusty, z approx.. 2 populations such as submillimeter-selected galaxies and dust-obscured galaxies. These traits are commonly associated with the dust being illuminated by intense active galactic nucleus activity. We hypothesize that the combination of spatially extended Ly-alpha, large amounts of warm IR-luminous dust, and rarity (implying a short-lived phase) can be explained if the galaxies are undergoing brief, intense "feedback" transforming them from an extreme dusty starburst/QSO into a mature galaxy.

  8. Lung cancer risk of low-level exposures to alpha emitters: critical reappraisal and experiments based on a new cytodynamic model

    Energy Technology Data Exchange (ETDEWEB)

    Bogen, Kenneth T. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    1999-02-20

    Ecologic U.S. county data suggest negative associations between residential radon exposure and lung cancer mortality (LCM)-inconsistent with clearly positive associations revealed by occupational data on individual miners, but perhaps explained by competing effects of cell killing vs. mutations in alpha-exposed bronchial epithelium. To assess the latter possibility, a biologically based "cytodynamic 2-stage" (CD2) cancer-risk model was fit to combined 1950-54 age- specific person-year data on lung cancer mortality (LCM) in white females of age 40+ y in 2,821 U.S. counties (-90% never-smokers), and in 5 cohorts of underground miners who never smoked. New estimates of household annual average radon exposure in U.S. counties were used, which were found to have a significant negative ecologic association with 1950-54 LCM in U.S. white females, adjusted for age and all subsets of two among 21 socioeconomic, climatic and other factors considered. A good CD2 fit was obtained to the combined residential/miner data, using biologically plausible parameter values. Without further optimization, the fit also predicted independent inverse dose-rate effects shown (for the first time) to occur in nonsmoking miners. Using the same U.S. county-level LCM data, a separate study revealed a positive ecologic association between LCM and bituminous coal use in the U.S., in agreement with epidemiological data on LCM in women in China. The modeling results obtained are consistent with the CD2-based hypothesis that residential radon exposure has a nonlinear U-shaped relation to LCM risk, and that current linear no-threshold extrapolation models substantially overestimate such risk. A U-shaped dose-response corresponds to a CD2-model prediction that alpha radiation kills more premalignant cells than it generates at low exposure levels, but not at higher levels. To test this hypothesis, groups of Japanese medaka (ricefish minnows) were exposed for 10 to 14 weeks to different concentrations of

  9. Aberration Corrected Emittance Exchange

    CERN Document Server

    Nanni, Emilio A

    2015-01-01

    Full exploitation of emittance exchange (EEX) requires aberration-free performance of a complex imaging system including active radio-frequency (RF) elements which can add temporal distortions. We investigate the performance of an EEX line where the exchange occurs between two dimensions with normalized emittances which differ by orders of magnitude. The transverse emittance is exchanged into the longitudinal dimension using a double dog-leg emittance exchange setup with a 5 cell RF deflector cavity. Aberration correction is performed on the four most dominant aberrations. These include temporal aberrations that are corrected with higher order magnetic optical elements located where longitudinal and transverse emittance are coupled. We demonstrate aberration-free performance of emittances differing by 4 orders of magnitude, i.e. an initial transverse emittance of $\\epsilon_x=1$ pm-rad is exchanged with a longitudinal emittance of $\\epsilon_z=10$ nm-rad.

  10. Accelerated Evolution of Ly$\\alpha$ Luminosity Function at $\\textit{z} \\gtrsim 7$ Revealed by the Subaru Ultra-Deep Survey for Ly$\\alpha$ Emitters at $\\textit{z}=7.3$

    CERN Document Server

    Konno, Akira; Ono, Yoshiaki; Shimasaku, Kazuhiro; Shibuya, Takatoshi; Furusawa, Hisanori; Nakajima, Kimihiko; Naito, Yoshiaki; Momose, Rieko; Yuma, Suraphong; Iye, Masanori

    2014-01-01

    We present the ultra-deep Subaru narrowband imaging survey for Lya emitters (LAEs) at $z=7.3$ in SXDS and COSMOS fields with a total integration time of 106 hours. Exploiting our new sharp bandwidth filter, NB101, installed on Suprime-Cam, we have reached $L(Lya)=2.4\\times10^{42} \\ erg \\ s^{-1}$ ($5\\sigma$) for $z=7.3$ LAEs, about 4 times deeper than previous Subaru $z \\gtrsim 7$ studies, which allows us to reliably investigate evolution of Lya luminosity function (LF), for the first time, down to the luminosity limit same as those of Subaru $z=3.1-6.6$ LAE samples. Surprisingly, we only find three and four LAEs in SXDS and COSMOS fields, respectively, while one expects a total of $\\sim 65$ LAEs by our survey in the case of no Lya LF evolution from $z=6.6$ to $7.3$.We identify a decrease of Lya LF from $z=6.6$ to $7.3$ at the $>90\\%$ confidence level from our $z=7.3$ Lya LF.Moreover, the evolution of Lya LF is clearly accelerated at $z>6.6$ beyond the measurement uncertainties including cosmic variance. Becau...

  11. A Randomized Multicentre Phase II Trial Comparing Adjuvant Therapy in Patients with Interferon Alpha-2b and 5-FU Alone or in Combination with Either External Radiation Treatment and Cisplatin (CapRI) or Radiation alone regarding Event-Free Survival – CapRI-2

    International Nuclear Information System (INIS)

    The 5-year survival of patients with resected pancreatic adenocarcinoma is still unsatisfying. The ESPAC-1 and the CONKO 001 trial proofed that adjuvant chemotherapy improves 5-year survival significantly from approximately 14% to 21%. In parallel, investigators from the Virginia Mason Clinic reported a 5-year survival rate of 55% in a phase II trial evaluating a combination of adjuvant chemotherapy, immunotherapy and external beam radiation (CapRI-scheme). Two other groups confirmed in phase II trials these results to a certain extent. However, these groups reported severe gastrointestinal toxicity (up to 93% grade 3 or 4 toxicity). In a randomized controlled phase III trial, called CapRI, 110 patients were enrolled from 2004 to 2007 in Germany and Italy to check for reproducibility. Interestingly, much less gastrointestinal toxicity was observed. However, dose-reduction due to haematological side effects had to be performed in nearly all patients. First clinical results are expected for the end of 2009. CapRI-2 is an open, controlled, prospective, randomized, multicentre phase II trial with three parallel arms. A de-escalation of the CapRI-scheme will be tested in two different modifications. Patients in study arm A will be treated as outpatients with the complete CapRI-scheme consisting of cisplatin, Interferon alpha-2b and external beam radiation and three cycles of 5-fluorouracil continuous infusion. In study arm B the first de-escalation will be realised by omitting cisplatin. Next, patients in study arm C will additionally not receive external beam radiation. A total of 135 patients with pathologically confirmed R0 or R1 resected pancreatic adenocarcinoma are planned to be enrolled. Primary endpoint is the comparison of the treatment groups with respect to six-month event-free-survival. An event is defined as grade 3 or grade 4 toxicity, objective tumour recurrence, or death. The aim of this clinical trial is to evaluate de-escalation of the CapRI-scheme. It

  12. Concurrent Supermassive Black Hole and Galazy Growth: Linking Environment and Nuclear Activity in Zeta Equals 2.23 H Alpha Emitters

    Science.gov (United States)

    Lehmer, B. D.; Lucy, A. B.; Alexander, D. M.; Best, P. N.; Geach, J. E.; Harrison, C. M.; Hornschemeier, A. E.; Matsuda, Y.; Mullaney, J. R.; Smail, Ian; Sobral, D.; Swinbank, A. M.

    2013-01-01

    We present results from an approximately equal 100 ks Chandra observation of the 2QZ Cluster 1004+00 structure at z = 2.23 (hereafter 2QZ Clus). 2QZ Clus was originally identified as an overdensity of four optically-selected QSOs at z = 2.23 within a 15 × 15 arcmin square region. Narrow-band imaging in the near-IR (within the K band) revealed that the structure contains an additional overdensity of 22 z = 2.23 H alpha-emitting galaxies (HAEs), resulting in 23 unique z = 2.23 HAEs/QSOs (22 within the Chandra field of view). Our Chandra observations reveal that three HAEs in addition to the four QSOs harbor powerfully accreting supermassive black holes (SMBHs), with 2-10 keV luminosities of approximately equal (8-60) × 10(exp 43) erg s(exp-1) and X-ray spectral slopes consistent with unobscured active galactic nucleus (AGN). Using a large comparison sample of 210 z = 2.23 HAEs in the Chandra-COSMOS field (C-COSMOS), we find suggestive evidence that the AGN fraction increases with local HAE galaxy density. The 2QZ Clus HAEs reside in a moderately overdense environment (a factor of approximately equal 2 times over the field), and after excluding optically-selected QSOs, we find that the AGN fraction is a factor of approximately equal 3.5(+3.8/ -2.2) times higher than C-COSMOS HAEs in similar environments. Using stacking analyses of the Chandra data and Herschel SPIRE observations at 250micrometers, we respectively estimate mean SMBH accretion rates ( M(BH)) and star formation rates (SFRs) for the 2QZ Clus and C-COSMOS samples. We find that the mean 2QZ Clus HAE stacked X-ray luminosity is QSO-like (L(2-10 keV) approximately equal [6-10] × 10(exp 43) erg s(exp -1)), and the implied M(BH)/SFR approximately equal (1.6-3.2) × 10(exp -3) is broadly consistent with the local M(BH)/Stellar Mass relation and z approximately equal 2 X-ray selected AGN. In contrast, the C-COSMOS HAEs are on average an order of magnitude less X-ray luminous and have M(BH)/SFR approximately

  13. Kinetic method for the determination of nanogram amounts of cadmium(II) by its catalytic effect on the complex formation of manganese(II) with. cap alpha. ,. beta. ,. gamma. , $delta-tetra-(p-sulfonatophenyl)porphine

    Energy Technology Data Exchange (ETDEWEB)

    Tabata, M. (Saga Univ. (Japan). Faculty of Science and Engineering); Tanaka, M. (Nagoya Univ. (Japan). Faculty of Science)

    1982-01-01

    Cadmium(II) accelerates the complex formation reaction of manganese(II) with ..cap alpha.., ..beta.., ..gamma.., $delta-tetra(p-sulfonatophenyl)porphine (H/sub 2/TPPS/sub 4/). Cadmium(II) concentration as low as 1O/sup -7/ mol dm/sup -3/ can be determined from the decrease in absorbance at 413 nm ($lambdasub(max) H/sub 2/TPPS/sub 4/) at a fixed time after the start of the reaction of manganese(II) with H/sub 2/TPPS/sub 4/. After the separation of lead(II) by coprecipitation of manganese(IV) oxide, the method is highly selective and is free from interference of most substances usually encountered. Sandell's sensitivity calculated from the calibration curve at 30 min after the start of the reaction is 1.43 x 10/sup -/ /sup 1/ ng cm/sup -2/.

  14. Evaluations of carbon nanotube field emitters for electron microscopy

    International Nuclear Information System (INIS)

    Brightness of carbon nanotube (CNT) emitters was already reported elsewhere. However, brightness of electron emitter is affected by a virtual source size of the emitter, which strongly depends on electron optical configuration around the emitter. In this work, I-V characteristics and brightness of a CNT emitter are measured under a practical field emission electron gun (e-gun) configuration to investigate availability of CNT for electron microscopy. As a result, it is obtained that an emission area of MWNT is smaller than its tip surface area, and the emission area corresponds to a five-membered-ring with 2nd nearest six-membered-rings on the MWNT cap surface. Reduced brightness of MWNT is measured as at least 2.6x109 A/m2 sr V. It is concluded that even a thick MWNT has enough brightness under a practical e-gun electrode configuration and suitable for electron microscopy.

  15. Death cap

    DEFF Research Database (Denmark)

    Rudbæk, Torsten R; Kofoed, Pernille Bouteloup; Bove, Jeppe;

    2014-01-01

    Death cap (Amanita phalloides) is commonly found and is one of the five most toxic fungi in Denmark. Toxicity is due to amatoxin, and poisoning is a serious medical condition, causing organ failure with potential fatal outcome. Acknowledgement and clarification of exposure, symptomatic and focused...

  16. Comparison of U.S. Environmental Protection Agency's CAP88 PC Versions 3.0 and 4.0.

    Science.gov (United States)

    Jannik, Tim; Farfan, Eduardo B; Dixon, Ken; Newton, Joseph; Sailors, Christopher; Johnson, Levi; Moore, Kelsey; Stahman, Richard

    2015-08-01

    The Savannah River National Laboratory (SRNL) with the assistance of Georgia Regents University, completed a comparison of the U.S. Environmental Protection Agency's (U.S. EPA) environmental dosimetry code CAP88 PC V3.0 with the recently developed V4.0. CAP88 is a set of computer programs and databases used for estimation of dose and risk from radionuclide emissions to air. At the U.S. Department of Energy's Savannah River Site, CAP88 is used by SRNL for determining compliance with U.S. EPA's National Emission Standards for Hazardous Air Pollutants (40 CFR 61, Subpart H) regulations. Using standardized input parameters, individual runs were conducted for each radionuclide within its corresponding database. Some radioactive decay constants, human usage parameters, and dose coefficients changed between the two versions, directly causing a proportional change in the total effective dose. A detailed summary for select radionuclides of concern at the Savannah River Site (60Co, 137Cs, 3H, 129I, 239Pu, and 90Sr) is provided. In general, the total effective doses will decrease for alpha/beta emitters because of reduced inhalation and ingestion rates in V4.0. However, for gamma emitters, such as 60Co and 137Cs, the total effective doses will increase because of changes U.S. EPA made in the external ground shine calculations. PMID:26102326

  17. Phase III trial of postoperative cisplatin, interferon alpha-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma – CapRI: study protocol [ISRCTN62866759

    Directory of Open Access Journals (Sweden)

    Schmitz-Winnenthal H

    2005-04-01

    Full Text Available Abstract After surgical intervention with curative intention in specialised centres the five-year survival of patients with carcinoma of the exocrine pancreas is only 15%. The ESPAC-1 trial showed an increased five-year survival of 21% achieved with adjuvant chemotherapy. Investigators from the Virginia Mason Clinic have reported a 5-year survival rate of 55% in a phase II trial evaluating adjuvant chemotherapy, immunotherapy and external-beam radiation. Design The CapRI study is an open, controlled, prospective, randomised multi-centre phase III trial. Patients in study arm A will be treated as outpatients with 5-Fluorouracil; Cisplatin and 3 million units Interferon alpha-2b for 5 1/2 weeks combined with external beam radiation. After chemo-radiation the patients receive continuous 5-FU infusions for two more cycles. Patients in study arm B will be treated as outpatients with intravenous bolus injections of folinic acid, followed by intravenous bolus injections of 5-FU given on 5 consecutive days every 28 days for 6 cycles. A total of 110 patients with specimen-proven R0 or R1 resected pancreatic adenocarcinoma will be enrolled. An interim analysis for patient safety reasons will be done one year after start of recruitment. Evaluation of the primary endpoint will be performed two years after the last patients' enrolment. Discussion The aim of this study is to evaluate the overall survival period attained by chemo-radiotherapy including interferon alpha 2b administration with adjuvant chemotherapy. The influence of interferon alpha on the effectiveness of the patients' chemoradiation regimen, the toxicity, the disease-free interval and the quality of life are analysed. Different factors are tested in terms of their potential role as predictive markers.

  18. Phase III trial of postoperative cisplatin, interferon alpha-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma – CapRI: study protocol [ISRCTN62866759

    International Nuclear Information System (INIS)

    After surgical intervention with curative intention in specialised centres the five-year survival of patients with carcinoma of the exocrine pancreas is only 15%. The ESPAC-1 trial showed an increased five-year survival of 21% achieved with adjuvant chemotherapy. Investigators from the Virginia Mason Clinic have reported a 5-year survival rate of 55% in a phase II trial evaluating adjuvant chemotherapy, immunotherapy and external-beam radiation. The CapRI study is an open, controlled, prospective, randomised multi-centre phase III trial. Patients in study arm A will be treated as outpatients with 5-Fluorouracil; Cisplatin and 3 million units Interferon alpha-2b for 5 1/2 weeks combined with external beam radiation. After chemo-radiation the patients receive continuous 5-FU infusions for two more cycles. Patients in study arm B will be treated as outpatients with intravenous bolus injections of folinic acid, followed by intravenous bolus injections of 5-FU given on 5 consecutive days every 28 days for 6 cycles. A total of 110 patients with specimen-proven R0 or R1 resected pancreatic adenocarcinoma will be enrolled. An interim analysis for patient safety reasons will be done one year after start of recruitment. Evaluation of the primary endpoint will be performed two years after the last patients' enrolment. The aim of this study is to evaluate the overall survival period attained by chemo-radiotherapy including interferon alpha 2b administration with adjuvant chemotherapy. The influence of interferon alpha on the effectiveness of the patients' chemoradiation regimen, the toxicity, the disease-free interval and the quality of life are analysed. Different factors are tested in terms of their potential role as predictive markers

  19. The DIORAMA Neutron Emitter

    Energy Technology Data Exchange (ETDEWEB)

    Terry, James Russell [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-05-05

    Emission of neutrons in a given event is modeled by the DioramaEmitterNeutron object, a subclass of the abstract DioramaEmitterModule object. The GenerateEmission method of this object is the entry point for generation of a neutron population for a given event. Shown in table 1, this method requires a number of parameters to be defined in the event definition.

  20. /sup 12/C(/sup 16/O,. cap alpha. )/sup 24/Mg( reaction in the energy region E/sub c. m. / = 26. 6 to 42. 9 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Bechara, M.J.; Lazzarini, A.J.; Ledoux, R.J.; Cosman, A.E.R.

    1983-04-01

    The /sup 12/C+ /sup 16/O resonance structure in the /sup 28/Si nucleus is examined by means of the /sup 12/C(/sup 16/O,..cap alpha..)/sup 2r/Mg reaction excitation functions in the energy range E/sub c.m./ = 26.6 to 42.9 MeV in 430 keV steps at theta/sub lab/ = 7.5/sup 0/. We could identify 64 discrete states in /sup 24/Mg up to 31.7 MeV of excitation energy. The excitation functions show abundant structure over the entire energy range. The summed excitation functions, which tend to average out statistical fluctuations, show pronounced intermediate structure enhancement in the cross section at E/sub c.m./approx. =29.5, 32.2, and 35 MeV and indicate the presence of a smaller peak at 37.3 MeV. The widths of these structures are about 1 MeV, which is intermediate between the value expected from ion-ion potential resonances and statistical fluctuations. The nonstatistical character of these structures is reinforced by some statistical tests and by the correlations in energy and width found in several exit channels. Our data also suggest a possible structural relationship between the /sup 28/Si resonances and certain /sup 24/Mg final states.

  1. Cancer from internal emitters

    International Nuclear Information System (INIS)

    Irradiation from internal emitters, or internally deposited radionuclides, is an important component of radiation exposures encountered in the workplace, home, or general environment. Long-term studies of human populations exposed to various internal emitters by different routes of exposure are producing critical information for the protection of workers and members of the general public. The purpose of this report is to examine recent developments and discuss their potential importance for understanding lifetime cancer risks from internal emitters. The major populations of persons being studied for lifetime health effects from internally deposited radionuclides are well known: Lung cancer in underground miners who inhaled Rn progeny, liver cancer from persons injected with the Th-containing radiographic contrast medium Thorotrast, bone cancer from occupational or medical intakes of 226Ra or medical injections of 224Ra, and thyroid cancer from exposures to iodine radionuclides in the environment or for medical purposes

  2. Comparison of U.S. Environmental Protection Agency's CAP88 PC versions 3.0 and 4.0

    International Nuclear Information System (INIS)

    The Savannah River National Laboratory (SRNL) with the assistance of Georgia Regents University, completed a comparison of the U.S. Environmental Protection Agency's (EPA) environmental dosimetry code CAP88 PC V3.0 with the recently developed V4.0. CAP88 is a set of computer programs and databases used for estimation of dose and risk from radionuclide emissions to air. At the U.S. Department of Energy's Savannah River Site, CAP88 is used by SRNL for determining compliance with EPA's National Emission Standards for Hazardous Air Pollutants (40 CFR 61, Subpart H) regulations. Using standardized input parameters, individual runs were conducted for each radionuclide within its corresponding database. Some radioactive decay constants, human usage parameters, and dose coefficients changed between the two versions, directly causing a proportional change in the total effective 137Cs, 3H, 129I, 239Pu, and 90Sr) is provided. In general, the total effective doses will decrease for alpha/beta emitters because of reduced inhalation and ingestion rates in V4.0. However, for gamma emitters, such as 60Co and 137Cs, the total effective doses will increase because of changes EPA made in the external ground shine calculations

  3. RFI emitter location techniques

    Science.gov (United States)

    Rao, B. L. J.

    1973-01-01

    The possibility is discussed of using Doppler techniques for determining the location of ground based emitters causing radio frequency interference with low orbiting satellites. An error analysis indicates that it is possible to find the emitter location within an error range of 2 n.mi. The parameters which determine the required satellite receiver characteristic are discussed briefly along with the non-real time signal processing which may by used in obtaining the Doppler curve. Finally, the required characteristics of the satellite antenna are analyzed.

  4. PENCIL LEAD FIELD EMITTER

    OpenAIRE

    Khairnar, R.; Joag, D.

    1989-01-01

    Field electron emission from 2H and HB grades of pencil lead has been studied. The pencil lead field emitter is found to obey the Fowler-Nordheim characteristics. The emission current fluctuations are found to increase with the residual gas pressure and the emission current. The current density of the order of 106 amp/cm2 could be drawn from these emitters. The emission stability over the operation of six hours has been found to be reasonably good. The field ion microscopy of the 2H and HB gr...

  5. Alpha voltaic batteries and methods thereof

    Science.gov (United States)

    Raffaelle, Ryne P. (Inventor); Jenkins, Phillip (Inventor); Wilt, David (Inventor); Scheiman, David (Inventor); Chubb, Donald (Inventor); Castro, Stephanie (Inventor)

    2011-01-01

    An alpha voltaic battery includes at least one layer of a semiconductor material comprising at least one p/n junction, at least one absorption and conversion layer on the at least one layer of semiconductor layer, and at least one alpha particle emitter. The absorption and conversion layer prevents at least a portion of alpha particles from the alpha particle emitter from damaging the p/n junction in the layer of semiconductor material. The absorption and conversion layer also converts at least a portion of energy from the alpha particles into electron-hole pairs for collection by the one p/n junction in the layer of semiconductor material.

  6. Synthesis of tritiated 1-alpha-methadol and 1-alpha-acetylmethadol

    Energy Technology Data Exchange (ETDEWEB)

    Thang, D.C.; Nam, N.H.; Pontikis, R. (Institut National de la Sante et de la Recherche Medicale (INSERM), Hopital Fernand Widal, 75 - Paris (France)); Pichat, L. (CEA Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France). Service des Molecules Marquees)

    1982-04-01

    dl-Methadone was resolved by crystallization of its ammonium d- ..cap alpha.. -bromocamphor-..pi..-sulfonate salt to give d-methadone. The latter in ethyl acetate solution was reduced with tritium gas to 1-..cap alpha..-methadol /sup 3/H in presence of Adams platinum oxide at normal temperature and pressure. Acetylation of 1-..cap alpha..-carbinol hydrochloride by means of acetyl chloride afforded 1-..cap alpha..-acetylmethadol /sup 3/H, specific activity: 20 Ci/mMole. The positions and extent of tritium labelling were determined by /sup 3/H NMR spectroscopy.

  7. Experimental Proof of Adjustable Single-Knob Ion Beam Emittance Partitioning

    CERN Document Server

    Groening, L; Xiao, C; Dahl, L; Gerhard, P; Kester, O K; Mickat, S; Vormann, H; Vossberg, M; Chung, M

    2014-01-01

    The performance of accelerators profits from phase space tailoring by coupling of planes. The previously applied techniques swap the emittances among the three planes but the set of available emittances is fixed. In contrast to these emittance exchange scenarios the emittance transfer scenario presented here allows for arbitrarily changing the set of emittances as long as the product of the emittances is preserved. This letter is on the first experimental demonstration of transverse emittance transfer along an ion beam line. The amount of transfer is chosen by setting just one single magnetic field value. The envelope-functions (beta) and -slopes (alpha) of the finally uncorrelated and re-partitioned beam at the exit of the transfer line do not depend on the amount of transfer.

  8. Helium precipitation in. cap alpha. -Fe

    Energy Technology Data Exchange (ETDEWEB)

    Caspers, L.M.; van Veen, A.; Ypma, M.R.; van der Kolk, G.J. (Interuniversitair Reactor Inst., Delft (Netherlands))

    1982-03-16

    The filling of a vacancy with helium atoms is studied with a programme simulating the relaxation of lattice atoms around the complex. Three filling modes are described. Helium filled V/sub 2/, V/sub 3/, and V/sub 4/ complexes are also considered and the energetics of the mutation reactions of He/sub n/V ..-->.. He/sub m>n/V/sub 2/ ..-->.. He/sub p>m/V/sub 3/ ..-->.. He/sub q>p/V/sub 4/ is studied. It is shown that these mutation reactions are more probable when the emitted interstitials remain bound to the mutation products. The He/sub n/V/sub m/I/sub p/ complexes thus formed are stable against reduction, in agreement with experiments. Also the formation of these complexes could explain why helium precipitation proceeds in a two-dimensional way as observed by TEM. The general trend found in helium desorption measurements viz. a decrease in helium binding energy until some 6 to 10 He atoms are trapped and thereafter an increase in binding energy is also found in this computer simulation study.

  9. Low-emittance Storage Rings

    CERN Document Server

    Wolski, A

    2014-01-01

    The effects of synchrotron radiation on particle motion in storage rings are discussed. In the absence of radiation, particle motion is symplectic, and the beam emittances are conserved. The inclusion of radiation effects in a classical approximation leads to emittance damping: expressions for the damping times are derived. Then, it is shown that quantum radiation effects lead to excitation of the beam emittances. General expressions for the equilibrium longitudinal and horizontal (natural) emittances are derived. The impact of lattice design on the natural emittance is discussed, with particular attention to the special cases of FODO-, achromat- and theoretical-minimum-emittance-style lattices. Finally, the effects of betatron coupling and vertical dispersion (generated by magnet alignment and lattice tuning errors) on the vertical emittance are considered.

  10. Directional Thermal Emitter Simulation

    OpenAIRE

    Dhaka, Shailja; Sakr, Enas Said; Bermel, Peter

    2015-01-01

    The development of renewable energy sources has attracted increasing interest because of negative externalities associated with fossil fuel use. Thermophotovoltaics is a promising technology, in which a thermal emitter radiates photons which are directly converted into electricity using a photovoltaic diode. However, blackbody emission includes a broad range of wavelengths, but only higher energy photons can be converted into electricity. Thus, tailoring the selectivity of thermal emission is...

  11. Dynamic carbon caps. Splitting the bill: A fairer solution post-Kyoto?

    International Nuclear Information System (INIS)

    A dynamic carbon cap scheme is described and illustrated using a future growth scenario. This scheme, called a 'bill-splitting dynamic carbon cap', uses national carbon caps that change in a manner designed to distribute burden equitably, and at the same time to encourage and feed off economic growth. This is achieved by distributing emission-reduction obligations away from the growers, and onto the emitters. The global emission-reduction response is thereby pegged to global growth.

  12. Monolithic multinozzle emitters for nanoelectrospray mass spectrometry

    Science.gov (United States)

    Wang, Daojing; Yang, Peidong; Kim, Woong; Fan, Rong

    2011-09-20

    Novel and significantly simplified procedures for fabrication of fully integrated nanoelectrospray emitters have been described. For nanofabricated monolithic multinozzle emitters (NM.sup.2 emitters), a bottom up approach using silicon nanowires on a silicon sliver is used. For microfabricated monolithic multinozzle emitters (M.sup.3 emitters), a top down approach using MEMS techniques on silicon wafers is used. The emitters have performance comparable to that of commercially-available silica capillary emitters for nanoelectrospray mass spectrometry.

  13. Emittance Measurement in MICE

    OpenAIRE

    Hart, Terrence L.; Kaplan, Daniel M.

    2008-01-01

    Muon ionization cooling provides the only practical solution to prepare high-brilliance beams necessary for a neutrino factory or muon collider. The Muon Ionization Cooling Experiment (MICE), under development at the Rutherford Appleton Laboratory, is installing the first set of particle detectors ever built to measure to 0.1% the emittance of a 200 MeV/c or so muon beam in and out of a cooling cell, and thus measure the cooling cell's performance. Two identical "emittometers" (a precise scin...

  14. Beam phase space and emittance

    International Nuclear Information System (INIS)

    The classical and elementary results for canonical phase space, the Liouville theorem and the beam emittance are reviewed. Then, the importance of phase portraits to obtain a geometrical description of motion is emphasized, with examples in accelerator physics. Finally, a statistical point of view is used to define beam emittance, to study its law of approximate conservation and to treat two particular examples

  15. Emittance growth in rf linacs

    International Nuclear Information System (INIS)

    As the space-charge limit is approached, the current that can be accelerated in an rf linac and the output emittance that can be expected are discussed. The role of the envelope equations to estimate limits is outlined. The results of numerical experiments to explore general properties of emittance growth are given

  16. Emittance Measurement in MICE

    CERN Document Server

    Hart, Terrence L

    2008-01-01

    Muon ionization cooling provides the only practical solution to prepare high-brilliance beams necessary for a neutrino factory or muon collider. The Muon Ionization Cooling Experiment (MICE), under development at the Rutherford Appleton Laboratory, is installing the first set of particle detectors ever built to measure to 0.1% the emittance of a 200 MeV/c or so muon beam in and out of a cooling cell, and thus measure the cooling cell's performance. Two identical "emittometers" (a precise scintillating-fiber tracker in solenoidal magnetic field and a 50 ps time-of-flight station) measure the six phase-space coordinates of each muon. Another TOF plane and two Cherenkov counters assure the purity of the incoming muon beam. A downstream electron/muon calorimeter eliminates contamination from decay electrons.

  17. Sets of Reports and Articles Regarding Cement Wastes Forms Containing Alpha Emitters that are Potentially Useful for Development of Russian Federation Waste Treatment Processes for Solidification of Weapons Plutonium MOX Fuel Fabrication Wastes for

    Energy Technology Data Exchange (ETDEWEB)

    Jardine, L J

    2003-06-12

    This is a set of nine reports and articles that were kindly provided by Dr. Christine A. Langton from the Savannah River Site (SRS) to L. J. Jardine LLNL in June 2003. The reports discuss cement waste forms and primarily focus on gas generation in cement waste forms from alpha particle decays. However other items such as various cement compositions, cement product performance test results and some cement process parameters are also included. This set of documents was put into this Lawrence Livermore National Laboratory (LLNL) releasable report for the sole purpose to provide a set of documents to Russian technical experts now beginning to study cement waste treatment processes for wastes from an excess weapons plutonium MOX fuel fabrication facility. The intent is to provide these reports for use at a US RF Experts Technical Meeting on: the Management of Wastes from MOX Fuel Fabrication Facilities, in Moscow July 9-11, 2003. The Russian experts should find these reports to be very useful for their technical and economic feasibility studies and the supporting R&D activities required to develop acceptable waste treatment processes for use in Russia as part of the ongoing Joint US RF Plutonium Disposition Activities.

  18. Beam emittance measurements in RHIC

    Energy Technology Data Exchange (ETDEWEB)

    Zelenski,A.; Bazilevsky, A.; Bunce, G.; Gill, R.; Huang, H.; Makdisi, Y.; Morozov, B.; Nemesure, S.; Russo, t.; Steski, D.; Sivertz, M.

    2009-05-04

    The RHIC proton polarimeters can operate in scanning mode, giving polarization profiles and transverse beam intensity profile (beam emittance) measurements. The polarimeters function as wire scanners, providing a very good signal/noise ratio and high counting rate. This allows accurate bunch-by-bunch emittance measurements during fast target sweeps (<1 s) through the beam. Very thin carbon strip targets make these measurements practically non-destructive. Bunch by bunch emittance measurements are a powerful tool for machine set-up; in RHIC, individual proton beam transverse emittances can only be measured by CNI polarimeter scans. We discuss the consistency of these measurements with Ionization Profile Monitors (IPMs) and vernier scan luminosity measurements. Absolute accuracy limitations and cross-calibration of different techniques are also discussed.

  19. Personnel exposure from positron emitters

    International Nuclear Information System (INIS)

    Positron emitters may contribute considerably to the radiation from induced radioactivity in accelerator environments. In most cases of thick radiating objects (magnets, shielding walls) the dose rate from gamma emitters, including the 511 keV annihilation photons from positron emitters, dominates the radiation field. Direct positron interaction in skin tissue and in the lens of the eye may be an important contribution to absorbed dose in cases of thin targets and beam separating septa. Results of calculations and measurements show, however, that the dose to the lens of the eye is limited by limitations placed on whole-body doses. Irradiation from positron emitters gives rise to about the same absorbed doses as those experienced in the case of an electron exposure. (author)

  20. Diamondoid monolayers as electron emitters

    Science.gov (United States)

    Yang, Wanli; Fabbri, Jason D.; Melosh, Nicholas A.; Hussain, Zahid; Shen, Zhi-Xun

    2012-04-10

    Provided are electron emitters based upon diamondoid monolayers, preferably self-assembled higher diamondoid monolayers. High intensity electron emission has been demonstrated employing such diamondoid monolayers, particularly when the monolayers are comprised of higher diamondoids. The application of such diamondoid monolayers can alter the band structure of substrates, as well as emit monochromatic electrons, and the high intensity electron emissions can also greatly improve the efficiency of field-effect electron emitters as applied to industrial and commercial applications.

  1. Microtubule's conformational cap

    DEFF Research Database (Denmark)

    Chretien, D.; Janosi, I.; Taveau, J.C.;

    1999-01-01

    The molecular mechanisms that allow elongation of the unstable microtubule lattice remain unclear. It is usually thought that the GDP-liganded tubulin lattice is capped by a small layer of GTP- or GDP-P(i)-liganded molecules, the so called "GTP-cap". Here, we point-out that the elastic properties...

  2. Analytical approximations for describing the interaction of charged particles with the emitter of a radioisotope current source

    CERN Document Server

    Altajskij, M V; Erokhin, N S; Zolnikova, N N; Mikhajlovskaya, L A; Moiseev, S S

    2002-01-01

    The approximation formulae for modeling the interaction of the fast alpha-particles and superthermal electrons with the solid-state plasma of the emitter films of the secondary emission radioisotope current source are developed. The evaluations of the interactions characteristic parameters, including the effective breaking efficiency of the emitter composite medium and the alpha-particles run, the emitter optimal thickness and maximum number of the current binary cells are accomplished on their basis. The obtained results may be used for optimizing the parameters of the experimental sample of such source and for the analysis of the problems, connected with its operation

  3. Emittance measurements on ETA and ATA

    International Nuclear Information System (INIS)

    Emittance measurements on beams produced by the ETA and ATA accelerators are discussed. Emittance and brightness are defined. The significance of emittance for a beam in an accelerator and in gas is discussed. Various measurement techniques and results are presented and contrasted. Implicit calculations of emittance are also reported. Finally, the measurement of the time variation of emittance is discussed and the techniques to be used on the upcoming ATA experiments are outlined

  4. Direct correlation between a negative autoregulatory response element at the cap site of the herpes simplex virus type 1 IE175 (alpha 4) promoter and a specific binding site for the IE175 (ICP4) protein.

    OpenAIRE

    Roberts, M S; Boundy, A; O'Hare, P; Pizzorno, M C; Ciufo, D M; Hayward, G S

    1988-01-01

    In transient-expression assays, the IE175 (alpha 4) promoter region of herpes simple virus is down-regulated after cotransfection with DNA encoding its own protein product (IE175 or ICP4). The inhibition by IE175 proved to be highly specific for its own promoter region and did not act on either the herpes simplex virus type 1 IE110 (alpha 0) or human cytomegalovirus major immediate-early promoters. Furthermore, the inhibition was still exhibited by IE175 effector plasmids driven by strong het...

  5. Study of the /sup 50/V nucleus with the (/sup 3/He,d), (/sup 3/He,. cap alpha. ), (/sup 3/He,p), and (/sup 3/He,p. gamma. ) reactions. [Angular distribution, 13 and 22 MeV, analog states, DWBA, J,. pi. , spectroscopic factors, angular momentum, transitions

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J W

    1971-06-01

    The nucleus /sup 50/V with a ground-state configuration (..pi..f/sub 7/2/)/sup 3/(..nu..f/sub 7/2/)/sup -1/ was studied with the /sup 49/Ti(/sup 3/He,d)/sup 50/V, /sup 51/V)/sup 3/He,..cap alpha..)/sup 50/V, and /sup 48/Ti(/sup 3/He,p)/sup 50/V, and /sup 48/Ti(/sup 3/He,p..gamma..)/sup 50/V reactions induced by the /sup 3/He/sup + +/ beam from the tandem Van de Graaff at the Argonne National Laboratory. The angular distributions from (/sup 3/He,d), (/sup 3/He,..cap alpha..), and (/sup 3/He,p) reactions induced by 22-MeV /sup 3/He were studied with overall energy resolution widths of 20, 30, and 42 keV, respectively. The reactions (/sup 3/He,p) and (/sup 3/He,p..gamma..) were also studied at an incident energy of 13 MeV to obtain the ..gamma.. decay of /sup 50/V levels (including two 0/sup +/ isobaric analog states) in which the neutron-proton pair is transferred with zero angular momentum. The angular distributions of the charged-particle reactions were analyzed with the distorted-wave Born approximation (DWBA), and spectroscopic factors have been extracted for the one-nucleon transfer reactions. The two-nucleon transfer reaction (/sup 3/He,p) was analyzed with the DWBA on the assumption that the neutron-proton pair is transferred as a deuteron. The angular momentum L/sub np/ of the transferred deuteron is established for most of the levels, and the possibility that several levels might have spin and parity 1/sup +/ is discussed.

  6. Alpha Schottky junction energy source

    Science.gov (United States)

    Litz, Marc S.; Fan, Zhaoyang; Carroll, James J.; Bayne, Stephen

    2012-06-01

    Isotope batteries offer solutions for long-lived low-power sensor requirements. Alpha emitting isotopes have energy per decay 103 times that of beta emitters. Alpha particles are absorbed within 20 μm of most materials reducing shielding mitigation. However, damage to materials from the alphas limits their practical use. A Schottky Barrier Diode (SBD) geometry is considered with an alpha emitting contact-layer on a diamond-like crystal semiconductor region. The radiation tolerance of diamond, the safety of alpha particles, combined with the internal field of the SBD is expected to generate current useful for low-power electronic devices over decades. Device design parameters and calculations of the expected current are described.

  7. CENTRIFUGE END CAP

    Science.gov (United States)

    Beams, J.W.; Snoddy, L.B.

    1960-08-01

    An end cap for ultra-gas centrifuges is designed to impart or remove angular momentum to or from the gas and to bring the entering gas to the temperature of the gas inside the centrifuge. The end cap is provided with slots or fins for adjusting the temperature and the angular momentum of the entering gas to the temperature and momentum of the gas in the centrifuge and is constructed to introduce both the inner and the peripheral stream into the centrifuge.

  8. Beam phase space and emittance

    International Nuclear Information System (INIS)

    The classical and elementary results for canonical phase space, the Liouville theorem and the beam emittance are reviewed. Then, the importance of phase portraits to obtain a geometrical description of motion is emphasized, with examples in accelerator physics. Finally, a statistical point of view is used to define beam emittance, to study its law of approximate conservation, with three particular examples, and to introduce a beam envelope-ellipse and the β-function, emphasing the statistical features of its properties. (author) 14 refs.; 11 figs

  9. Combustion powered thermophotovoltaic emitter system

    Energy Technology Data Exchange (ETDEWEB)

    McHenry, R.S. [Naval Academy, Annapolis, MD (United States). Naval Architecture, Ocean and Marine Engineering

    1995-07-01

    The US Naval Academy (USNA) has recently completed an engineering design project for a high temperature thermophotovoltaic (TPV) photon emitter. The final apparatus was to be portable, completely self contained, and was to incorporate cycle efficiency optimization such as exhaust stream recuperation. Through computer modeling and prototype experimentation, a methane fueled emitter system was designed from structural ceramic materials to fulfill the high temperature requirements necessary for high system efficiency. This paper outlines the engineering design process, discusses obstacles and solutions encountered, and presents the final design.

  10. CAPS Simulation Environment Development

    Science.gov (United States)

    Murphy, Douglas G.; Hoffman, James A.

    2005-01-01

    The final design for an effective Comet/Asteroid Protection System (CAPS) will likely come after a number of competing designs have been simulated and evaluated. Because of the large number of design parameters involved in a system capable of detecting an object, accurately determining its orbit, and diverting the impact threat, a comprehensive simulation environment will be an extremely valuable tool for the CAPS designers. A successful simulation/design tool will aid the user in identifying the critical parameters in the system and eventually allow for automatic optimization of the design once the relationships of the key parameters are understood. A CAPS configuration will consist of space-based detectors whose purpose is to scan the celestial sphere in search of objects likely to make a close approach to Earth and to determine with the greatest possible accuracy the orbits of those objects. Other components of a CAPS configuration may include systems for modifying the orbits of approaching objects, either for the purpose of preventing a collision or for positioning the object into an orbit where it can be studied or used as a mineral resource. The Synergistic Engineering Environment (SEE) is a space-systems design, evaluation, and visualization software tool being leveraged to simulate these aspects of the CAPS study. The long-term goal of the SEE is to provide capabilities to allow the user to build and compare various CAPS designs by running end-to-end simulations that encompass the scanning phase, the orbit determination phase, and the orbit modification phase of a given scenario. Herein, a brief description of the expected simulation phases is provided, the current status and available features of the SEE software system is reported, and examples are shown of how the system is used to build and evaluate a CAPS detection design. Conclusions and the roadmap for future development of the SEE are also presented.

  11. Radiation dosimetry in radiotherapy with internal emitters

    Energy Technology Data Exchange (ETDEWEB)

    Stabin, Michael G. [Oak Ridge Inst. for Science and Education, TN (United States)

    1997-12-31

    Full text. Radiation dosimetry radionuclides are currently being labeled to various biological agents used in internal emitter radiotherapy. This talk will review the various technologies and types of radiolabel in current use, with focus on the characterization of the radiation dose to the various important tissues of the body. Methods for obtaining data, developing kinetic models, and calculating radiation doses will be reviewed. Monoclonal antibodies are currently being labeled with both alpha and beta emitting radionuclides in attempts to find effective agents against cancer. Several radionuclides are also being used as bone pain palliation agents. These agents must be studied in clinical trials to determine the biokinetics and radiation dosimetry prior to approval for general use. In such studies, it is important to ensure the collection of the appropriate kinds of data and to collect the data at appropriate time intervals. The uptake and retention of activity in all significant source organs and in excreta be measured periodically (with at least 2 data points phase of uptake or clearance). Then, correct dosimetry methods must be applied - the best available methods for characterizing the radionuclide kinetic and for estimating the dosimetry in the various organs of the body especially the marrow, should be used. Attempts are also under way to develop methods for estimating true patient-specific dosimetry. Cellular and animal studies are also. Valuable in evaluating the efficacy of the agents in shrinking or eliminating tumors; some results from such studies will also be discussed. The estimation of radiation doses to patients in therapy with internal emitters involves several complex phases of analysis. Careful attention to detail and the use of the best available methods are essential to the protection of the patient and a successful outcome

  12. Ultra Low Emittance Light Sources

    Energy Technology Data Exchange (ETDEWEB)

    Bengtsson,J.

    2008-06-23

    This paper outlines the special issues for reaching sub-nm emittance in a storage ring. Effects of damping wigglers, intra-beam scattering and lifetime issues, dynamic aperture optimization, control of optics, and their interrelations are covered in some detail. The unique choices for the NSLS-II are given as one example.

  13. Properties of Lya Emitters Around the Radio Galaxy MRC 0316-257

    Energy Technology Data Exchange (ETDEWEB)

    Venemans, B; Rottgering, H; Miley, G; Kurk, J; De Breuck, C; van Breugel, W; Carilli, C; Ford, H; Heckman, T; Pentericci, L; McCarthy, P

    2004-08-12

    Observations of the radio galaxy MRC 0316-257 at z = 3.13 and the surrounding field are presented. Using narrow- and broad-band imaging obtained with the VLT*, 92 candidate Ly{alpha} emitters with a rest-frame equivalent width of > 15 AngstromS were selected in a {approx} 7{prime} x 7{prime} field around the radio galaxy. Spectroscopy of 40 candidate emitters resulted in the discovery of 33 emission line galaxies of which 31 are Ly{alpha} emitters with redshifts similar to that of the radio galaxy, while the remaining two galaxies turned out to be [{omicron} II] emitters. The Ly{alpha} profiles had widths (FWHM) corresponding to 120-800 kms{sup -1},with a median of 260 kms{sup -1}. Where the signal-to-noise spectra was large enough, the Ly{alpha} profiles are found to be asymmetric, with apparent absorption troughs blueward of the profile peaks, indicative of absorption along the line of sight of an {Eta}{Iota} mass of 1-5000 {mu}{circle_dot}. Besides that of the radio galaxy and one of the emitters that is an QSO, the continuum of the emitters is faint, with luminosities ranging from 1.3 L{sub *} to < 0.03 L{sub *}.The colors of the confirmed emitters are, on average, very blue. The median UV continuum slope is {beta}=-1.65, bluer than the average slope of LBGs with Ly{alpha} emitters is 2.6 {Mu}{circle_dot}{sup -1} as measured by the Ly{alpha} emission line or < 3.9 {Mu}{circle_dot}{sup -1} as measured by the UV continuum. The properties of the Ly{alpha} galaxies (faint, blue and small) are consistent with young star forming galaxies which are nearly dust free. The density of Ly{alpha} emitting galaxies in the field around MRC 0316-257 is a factor of 3.3{sup +0.5}{sub -0.4} larger compared with the density of Ly{alpha} emitters at that redshift. The velocity distribution of the spectroscopically confirmed emitters has a dispersion of 640 km s{sup -1}, corresponding to a FWHM of 1510 km s{sup -1}, which is substantially smaller than the width of the narrow

  14. Shielding in ungated field emitter arrays

    International Nuclear Information System (INIS)

    Cathodes consisting of arrays of high aspect ratio field emitters are of great interest as sources of electron beams for vacuum electronic devices. The desire for high currents and current densities drives the cathode designer towards a denser array, but for ungated emitters, denser arrays also lead to increased shielding, in which the field enhancement factor β of each emitter is reduced due to the presence of the other emitters in the array. To facilitate the study of these arrays, we have developed a method for modeling high aspect ratio emitters using tapered dipole line charges. This method can be used to investigate proximity effects from similar emitters an arbitrary distance away and is much less computationally demanding than competing simulation approaches. Here, we introduce this method and use it to study shielding as a function of array geometry. Emitters with aspect ratios of 102–104 are modeled, and the shielding-induced reduction in β is considered as a function of tip-to-tip spacing for emitter pairs and for large arrays with triangular and square unit cells. Shielding is found to be negligible when the emitter spacing is greater than the emitter height for the two-emitter array, or about 2.5 times the emitter height in the large arrays, in agreement with previously published results. Because the onset of shielding occurs at virtually the same emitter spacing in the square and triangular arrays, the triangular array is preferred for its higher emitter density at a given emitter spacing. The primary contribution to shielding in large arrays is found to come from emitters within a distance of three times the unit cell spacing for both square and triangular arrays

  15. Successful treatment of cap polyposis with infliximab.

    Science.gov (United States)

    Bookman, Ian D; Redston, Mark S; Greenberg, Gordon R

    2004-06-01

    Cap polyposis is a disorder characterized by bloody diarrhea with rectosigmoid polyps covered by a cap of fibropurulent exudate. The pathogenesis is unknown, but histological features suggest that mucosal prolapse may play a role. Drug therapies are usually unsuccessful, and treatment requires sigmoid resection or, if the disease recurs after initial surgical resection, panproctocolectomy. We report the case of a 36-year-old woman with characteristic clinical, endoscopic, and histological features of cap polyposis. Investigations included normal anorectal manometry and defecography, without evidence of prolapse. The patient's disease was unresponsive to treatment with mesalamine, antibiotics, lidocaine enemas, and corticosteroids. One infusion of infliximab 5 mg/kg provided dramatic symptomatic improvement but minimal endoscopic or histological change. After 4 infliximab infusions at 8-week intervals, endoscopy of the rectum and sigmoid colon was normal, and biopsies showed complete histological resolution of the inflammatory process. Well-being with normal endoscopy and histology has been maintained at 38 months, without further treatment. It was concluded that infliximab is effective therapy for cap polyposis and avoids the requirement for surgery. No clinical evidence was obtained to support mucosal prolapse as a causative factor, but the response to infliximab suggests a role for tumor necrosis factor-alpha in the pathogenesis of this disorder. PMID:15188181

  16. Determination of alpha-emitters in Brazilian tobacco

    International Nuclear Information System (INIS)

    The decay products of uranium and thorium natural series are widely distributed in all the terrestrial crust. Their concentrations are considerable in the phosphates utilized as fertilizer in the Brazilian agriculture. In this work analysis was performed on 238U, 234U, 232Th, 226Ra and 210Po in 22 Brazilian tobacco samples. The results showed 238U and 234U are in isotopic activity equilibrium (0.5±0.2 mBq/g). The equilibrium was not reached in the case of thorium isotopes: the 228/232Th ratio was about 6.4. The average values obtained were 34.3 mBq/g for 228Th and 5.4 mBq/g for 232Th. The 226Ra values were higher than its radioactive precursor, 238U. This can be explained by the high affinity of radium to tobacco plant and the uranium removal during physical and chemical processes. The high concentration of 210 Po(20 mBq/g) in tobacco samples may be due to radon daughter products being electrically charged and then attaching themselves to inert dusts, which then become attached to tiny hairs on tobacco leaves. The results of this work are consistent with values presented in specialized literature. (author) 15 refs.; 4 tabs

  17. Test chamber for alpha spectrometry

    Science.gov (United States)

    Larsen, Robert P.

    1977-01-01

    Alpha emitters for low-level radiochemical analysis by measurement of alpha spectra are positioned precisely with respect to the location of a surface-barrier detector by means of a chamber having a removable threaded planchet holder. A pedestal on the planchet holder holds a specimen in fixed engagement close to the detector. Insertion of the planchet holder establishes an O-ring seal that permits the chamber to be pumped to a desired vacuum. The detector is protected against accidental contact and resulting damage.

  18. The preservation of low emittance flat beams

    International Nuclear Information System (INIS)

    Many future linear collider designs require beams with very small transverse emittances and large emittance ratios εx much-gt εy. In this paper, we will discuss issues associated with the preservation of these small emittances during the acceleration of the beams. The primary sources of transverse emittance dilution in a high energy linear accelerator are the transverse wakefields, the dispersive errors, RF deflections, and betatron coupling. We will discuss the estimation of these effects and the calculation of tolerances that will limit the emittance dilution with a high degree of confidence. Since the six-dimensional emittance is conserved and only the projected emittances are increased, these dilutions can be corrected if the beam has not filamented (phase mixed). We discuss methods of correcting the dilutions and easing the tolerances with beam-based alignment and steering techniques, and non-local trajectory bumps. Finally, we discuss another important source of luminosity degradation, namely, pulse-to-pulse jitter

  19. Beam emittance and beam disruption

    International Nuclear Information System (INIS)

    Beam disruption during the collision of intense relativistic bunches has been studied by R. Hollebeek. In the case of oppositely charged bunches, focussing effects occur causing a decrease in the effective bunch cross section, and thereby an increase of luminosity by an enhancement factor H. The term disruption derives from the fact that the beam emittance changes markedly during the collision. 1 ref., 1 fig., 1 tab

  20. Beta emitters and radiation protection

    DEFF Research Database (Denmark)

    Jødal, Lars

    2009-01-01

    , and 90Y, using data from a freely available database. Bremsstrahlung yields were calculated for 90Y shielded by lead, aluminium, or perspex. Bremsstrahlung spectrum from 90Y shielded by perspex was measured, and attenuation of spectrum by lead was calculated. Whole-body and finger doses to persons...... the outside of the primary shielding material. If suitable shielding is used and larger numbers of handlings are divided among several persons, then handling of beta emitters can be a safe procedure....

  1. Beam emittance measurements at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Wendt, Manfred; Eddy, Nathan; Hu, Martin; Scarpine, Victor; Syphers, Mike; Tassotto, Gianni; Thurman-Keup, Randy; Yang, Ming-Jen; Zagel, James; /Fermilab

    2008-01-01

    We give short overview of various beam emittance measurement methods, currently applied at different machine locations for the Run II collider physics program at Fermilab. All these methods are based on beam profile measurements, and we give some examples of the related instrumentation techniques. At the end we introduce a multi-megawatt proton source project, currently under investigation at Fermilab, with respect to the beam instrumentation challenges.

  2. Source preparations for alpha and beta measurements

    Energy Technology Data Exchange (ETDEWEB)

    Holm, E. [Risoe National Lab., Roskilde (Denmark)

    2001-01-01

    Regarding alpha particle emitters subject for environmental studies, electrodeposition or co-precipitation as fluorides are the most common methods. For electro deposition stainless steel is generally used as cathode material but also other metals such as Ni, Ag, and Cu showed promising results. The use of other anode material than platinum, such as graphite should be investigated. For other purposes such as optimal resolution other more sophisticated methods are used but often resulting in poorer recovery. For beta particle emitters the type of detection system will decide the source preparation. Similar methods as for alpha particle emitters, electrodeposition or precipitation techniques can be used. Due to the continuous energy distribution of the beta pulse height distribution a high resolution is not required. Thicker sources from the precipitates or a stable isotopic carrier can be accepted but correction for absorption in the source must be done. (au)

  3. Source preparations for alpha and beta measurements

    International Nuclear Information System (INIS)

    Regarding alpha particle emitters subject for environmental studies, electrodeposition or co-precipitation as fluorides are the most common methods. For electro deposition stainless steel is generally used as cathode material but also other metals such as Ni, Ag, and Cu showed promising results. The use of other anode material than platinum, such as graphite should be investigated. For other purposes such as optimal resolution other more sophisticated methods are used but often resulting in poorer recovery. For beta particle emitters the type of detection system will decide the source preparation. Similar methods as for alpha particle emitters, electrodeposition or precipitation techniques can be used. Due to the continuous energy distribution of the beta pulse height distribution a high resolution is not required. Thicker sources from the precipitates or a stable isotopic carrier can be accepted but correction for absorption in the source must be done. (au)

  4. Intraperitoneal alpha-radioimmunotherapy in mice using different specific activities

    DEFF Research Database (Denmark)

    Elgqvist, Jörgen; Andersson, Håkan; Haglund, Elin; Jensen, Holger; Kahu, Helena; Lindegren, Sture; Warnhammar, Elisabet; Hultborn, Ragnar

    2009-01-01

    The aim of this study was to investigate the therapeutic efficacy of the alpha-radioimmunotherapy of ovarian cancer in mice, using different specific activities. This study was performed by using the monoclonal antibody, MX35 F(ab')(2), labeled with the alpha-particle-emitter, 211At....

  5. Repeated Intraperitoneal alpha-Radioimmunotherapy of Ovarian Cancer in Mice

    DEFF Research Database (Denmark)

    Elgqvist, Jörgen; Andersson, Håkan; Jensen, Holger; Kahu, Helena; Lindegren, Sture; Warnhammar, Elisabet; Hultborn, Ragnar

    2010-01-01

    The aim of this study was to investigate the therapeutic efficacy of alpha-radioimmunotherapy of ovarian cancer in mice using different fractionated treatment regimens. The study was performed using the monoclonal antibody MX35 F(ab')(2) labeled with the alpha-particle emitter (211)At. Methods...

  6. Coefficient Alpha

    OpenAIRE

    Panayiotis Panayides

    2013-01-01

    Heavy reliance on Cronbach’s alpha has been standard practice in many validation studies. However, there seem to be two misconceptions about the interpretation of alpha. First, alpha is mistakenly considered as an indication of unidimensionality and second, that the higher the value of alpha the better. The aim of this study is to clarify these misconceptions with the use of real data from the educational setting. Results showed that high alpha values can be obtained in multidimensional scale...

  7. Performance of blasting caps

    Science.gov (United States)

    Bement, Laurence J. (Inventor); Schimmel, Morry L. (Inventor); Perry, Ronnie B. (Inventor)

    1993-01-01

    Common blasting caps are made from an aluminum shell in the form of a tube which is closed at both ends. One end, which is called the output end, terminates in a principal side or face, and contains a detonating agent which communicates with a means for igniting the detonating agent. The improvement of the present invention is a flat, steel foil bonded to the face in a position which is aligned perpendicularly to the longitudinal axis of the tube.

  8. Alpha Decay Width of $^{212}$Po from a quartetting wave function approach

    CERN Document Server

    Xu, Chang; Röpke, G; Schuck, P; Funaki, Y; Horiuchi, H; Tohsaki, A; Yamada, T; Zhou, Bo

    2015-01-01

    A microscopic calculation of $\\alpha$-cluster preformation probability and $\\alpha$ decay width in the typical $\\alpha$ emitter $^{212}$Po is presented. Results are obtained by improving a recent approach to describe $\\alpha$ preformation in $^{212}$Po [Phys. Rev. C 90, 034304 (2014)] implementing four-nucleon correlations (quartetting). Using the actually measured density distribution of the $^{208}$ Pb core, the calculated alpha decay width of $^{212}$Po agrees fairly well with the measured one.

  9. Emittance minimisation with longitudinal dipole field variation

    International Nuclear Information System (INIS)

    The reduction of horizontal emittance beyond the conventional limit is pursued by introducing a longitudinal variation of the field in a bending magnet. For a given dipole field, the search for the minimal emittance is formulated analytically under different boundary conditions, starting from the achromat condition, preferred for light source rings. With a dipole field rapidly decaying along the longitudinal position, it is shown that the emittance can be further reduced, essentially by rendering the H function to be out of phase with the third power of the local curvature. Under the minimal emittance condition analytically obtained, the optimal dipole field distribution is searched numerically with a polynomial function, analysing at the same time the mechanism of the emittance reduction. The minimal emittance is argued as a function of the required peak field and the field distribution. Adaptability of longitudinally varying dipole fields in a standard magnet lattice for light sources is also addressed

  10. Capping the Mortgage Interest Deduction

    OpenAIRE

    Anderson, John E.; Clemens, Jeffrey; Hanson, Andrew

    2007-01-01

    In this paper we examine the economic implications of several policy options for capping the mortgage interest deduction (MID). We extend the standard user–cost model of owner–occupied housing to include a cap on the mortgage size receiving tax–favored status. Our user–cost estimates for taxpayers with mortgages above the current–law cap are 4.41 percent higher than estimates from a model without the cap. We simulate the share of mortgage dollars that would be subject to three alternative cap...

  11. Emittance measurements by variable quadrupole method

    International Nuclear Information System (INIS)

    The beam emittance is a measure of both the beam size and beam divergence, we cannot directly measure its value. If the beam size is measured at different locations or under different focusing conditions such that different parts of the phase space ellipse will be probed by the beam size monitor, the beam emittance can be determined. An emittance measurement can be performed by different methods. Here we will consider the varying quadrupole setting method.

  12. Faint Lyα Emitters, Star-forming Galaxies, and Damped Lyα Systems

    Science.gov (United States)

    Rauch, M.; Haehnelt, M.; Bunker, A.; Becker, G.; Marleau, F.; Graham, J.; Cristiani, S.; Jarvis, M.; Lacey, C.; Morris, S.; Peroux, C.; Roettgering, H.; Theuns, T.

    2008-10-01

    We have discovered a population of faint single line emitters, likely to be identified with faint z˜ 3 Lyα emitters and with the host galaxies of damped Lyman alpha systems. The objects appear to constitute the bulk of the star-forming galaxies detected so far from the ground, and are likely to provide the gaseous reservoir from which present-day Milky way type galaxies have formed. Unlike color-selected (yman break galaxies, these objects appear to have low star-formation rates, relatively strong Lyalpha emission, and low masses, metallicities, and dust content (s.a. arXiv:0711.1354).

  13. Saltstone Clean Cap Formulation

    Energy Technology Data Exchange (ETDEWEB)

    Langton, C

    2005-04-22

    The current operation strategy for using Saltstone Vault 4 to receive 0.2 Ci/gallon salt solution waste involves pouring a clean grout layer over the radioactive grout prior to initiating pour into another cell. This will minimize the radiating surface area and reduce the dose rate at the vault and surrounding area. The Clean Cap will be used to shield about four feet of Saltstone poured into a Z-Area vault cell prior to moving to another cell. The minimum thickness of the Clean Cap layer will be determined by the cesium concentration and resulting dose levels and it is expected to be about one foot thick based on current calculations for 0.1 Ci Saltstone that is produced in the Saltstone process by stabilization of 0.2 Ci salt solution. This report documents experiments performed to identify a formulation for the Clean Cap. Thermal transient calculations, adiabatic temperature rise measurements, pour height, time between pour calculations and shielding calculations were beyond the scope and time limitations of this study. However, data required for shielding calculations (composition and specific gravity) are provided for shielding calculations. The approach used to design a Clean Cap formulation was to produce a slurry from the reference premix (10/45/45 weight percent cement/slag/fly ash) and domestic water that resembled as closely as possible the properties of the Saltstone slurry. In addition, options were investigated that may offer advantages such as less bleed water and less heat generation. The options with less bleed water required addition of dispersants. The options with lower heat contained more fly ash and less slag. A mix containing 10/45/45 weight percent cement/slag/fly ash with a water to premix ratio of 0.60 is recommended for the Clean Cap. Although this mix may generate more than 3 volume percent standing water (bleed water), it has rheological, mixing and flow properties that are similar to previously processed Saltstone. The recommended

  14. Saltstone Clean Cap Formulation

    International Nuclear Information System (INIS)

    The current operation strategy for using Saltstone Vault 4 to receive 0.2 Ci/gallon salt solution waste involves pouring a clean grout layer over the radioactive grout prior to initiating pour into another cell. This will minimize the radiating surface area and reduce the dose rate at the vault and surrounding area. The Clean Cap will be used to shield about four feet of Saltstone poured into a Z-Area vault cell prior to moving to another cell. The minimum thickness of the Clean Cap layer will be determined by the cesium concentration and resulting dose levels and it is expected to be about one foot thick based on current calculations for 0.1 Ci Saltstone that is produced in the Saltstone process by stabilization of 0.2 Ci salt solution. This report documents experiments performed to identify a formulation for the Clean Cap. Thermal transient calculations, adiabatic temperature rise measurements, pour height, time between pour calculations and shielding calculations were beyond the scope and time limitations of this study. However, data required for shielding calculations (composition and specific gravity) are provided for shielding calculations. The approach used to design a Clean Cap formulation was to produce a slurry from the reference premix (10/45/45 weight percent cement/slag/fly ash) and domestic water that resembled as closely as possible the properties of the Saltstone slurry. In addition, options were investigated that may offer advantages such as less bleed water and less heat generation. The options with less bleed water required addition of dispersants. The options with lower heat contained more fly ash and less slag. A mix containing 10/45/45 weight percent cement/slag/fly ash with a water to premix ratio of 0.60 is recommended for the Clean Cap. Although this mix may generate more than 3 volume percent standing water (bleed water), it has rheological, mixing and flow properties that are similar to previously processed Saltstone. The recommended

  15. Directional emittance corrections for thermal infrared imaging

    Science.gov (United States)

    Daryabeigi, Kamran; Wright, Robert E., Jr.; Puram, Chith K.; Alderfer, David W.

    1992-01-01

    A simple measurement technique for measuring the variation of directional emittance of surfaces at various temperatures using commercially available radiometric IR imaging systems was developed and tested. This technique provided the integrated value of directional emittance over the spectral bandwidth of the IR imaging system. The directional emittance of flat black lacquer and red stycast, an epoxy resin, measured using this technique were in good agreement with the predictions of the electromagnetic theory. The data were also in good agreement with directional emittance data inferred from directional reflectance measurements made on a spectrophotometer.

  16. Hybrid emitter all back contact solar cell

    Science.gov (United States)

    Loscutoff, Paul; Rim, Seung

    2016-04-12

    An all back contact solar cell has a hybrid emitter design. The solar cell has a thin dielectric layer formed on a backside surface of a single crystalline silicon substrate. One emitter of the solar cell is made of doped polycrystalline silicon that is formed on the thin dielectric layer. The other emitter of the solar cell is formed in the single crystalline silicon substrate and is made of doped single crystalline silicon. The solar cell includes contact holes that allow metal contacts to connect to corresponding emitters.

  17. Emittance investigation of RF photo-injector

    CERN Document Server

    Yang Mao Rong; Li Zheng; Li Ming; Xu Zhou

    2002-01-01

    A high-power laser beam illuminates a photocathode surface placed on an end wall of an RF cavity. The emitted electrons are accelerated immediately to a relativistic energy by the strong RF find in the cavity. But space charge effect induces beam emittance growth especially near the cathode where the electrons are still nonrelativistic. The author analyzes the factors which lead the transverse emittance growth and method how to resolve this problem. After introducing solenoidal focusing near the photocathode, the beam emittance growth is suppressed dramatically. The beam emittance is given also after compensation and simulation results. The measurements show these results are coincident

  18. Muon Cooling—emittance exchange

    Science.gov (United States)

    Parsa, Zohreh

    2001-05-01

    Muon Cooling is the key factor in building of a Muon collider, (to a less degree) Muon storage ring, and a Neutrino Factory. Muon colliders potential to provide a probe for fundamental particle physics is very interesting, but may take a considerable time to realize, as much more work and study is needed. Utilizing high intensity Muon sources-Neutrino Factories, and other intermediate steps are very important and will greatly expand our abilities and confidence in the credibility of high energy muon colliders. To obtain the needed collider luminosity, the phase-space volume must be greatly reduced within the muon life time. The Ionization cooling is the preferred method used to compress the phase space and reduce the emittance to obtain high luminosity muon beams. We note that, the ionization losses results not only in damping, but also heating. The use of alternating solenoid lattices has been proposed, where the emittance are large. We present an overview of the cooling and discuss formalism, solenoid magnets and some beam dynamics.

  19. Bright Single Photon Emitter in Silicon Carbide

    Science.gov (United States)

    Lienhard, Benjamin; Schroeder, Tim; Mouradian, Sara; Dolde, Florian; Trong Tran, Toan; Aharonovich, Igor; Englund, Dirk

    Efficient, on-demand, and robust single photon emitters are of central importance to many areas of quantum information processing. Over the past 10 years, color centers in solids have emerged as excellent single photon emitters. Color centers in diamond are among the most intensively studied single photon emitters, but recently silicon carbide (SiC) has also been demonstrated to be an excellent host material. In contrast to diamond, SiC is a technologically important material that is widely used in optoelectronics, high power electronics, and microelectromechanical systems. It is commercially available in sizes up to 6 inches and processes for device engineering are well developed. We report on a visible-spectrum single photon emitter in 4H-SiC. The emitter is photostable at both room and low temperatures, and it enables 2 million photons/second from unpatterned bulk SiC. We observe two classes of orthogonally polarized emitters, each of which has parallel absorption and emission dipole orientations. Low temperature measurements reveal a narrow zero phonon line with linewidth < 0.1 nm that accounts for more than 30% of the total photoluminescence spectrum. To our knowledge, this SiC color emitter is the brightest stable room-temperature single photon emitter ever observed.

  20. TPV Systems with Solar Powered Tungsten Emitters

    International Nuclear Information System (INIS)

    A solar TPV generator development and characterization are presented. A double stage sunlight concentrator ensures 4600x concentration ratio. TPV modules based on tungsten emitters and GaSb cells were designed, fabricated and tested at indoor and outdoor conditions. The performance of tungsten emitter under concentrated solar radiation was analyzed. Emitter temperatures in the range of 1400-2000 K were measured, depending on the emitter size. The light distribution in the module has been characterized, 1x1 cm GaSb TPV cells were fabricated with the use of the Zn-diffusion and LPE technologies. The cell efficiency of 19% under illumination by a tungsten emitter (27% under spectra cut-off at λ > 1820 nm) heated up to 1900-2000 K had been derived from experimentally measured PV parameters. The series connection of PV cells was ensured by the use of BeO ceramics. The possibilities of system performance improvement are discussed

  1. Batch By Batch Longitudinal Emittance Blowup MD

    CERN Document Server

    Mastoridis, T; Butterworth, A; Jaussi, M; Molendijk, J

    2012-01-01

    The transverse bunch emittance increases significantly at 450 GeV from the time of injection till the ramp due to IBS. By selectively blowing up the longitudinal emittance of the incoming batch at each injection, it should be possible to reduce the transverse emittance growth rates due to IBS. An MD was conducted on April 22nd 2012 to test the feasibility and performance of the batch-by-batch longitudinal emittance blowup. There were three main goals during the MD. First, to test the developed hardware, firmware, and software for the batch-by-batch blowup. Then, to measure the transverse emittance growth rates of blown-up and "witness" batches to quantify any improvement, and finally to test the ALLInjectSequencer class, which deals with the complicated gymnastics of introducing or masking the new batch to various RF loops.

  2. Perspectives on the CAP Theorem

    OpenAIRE

    Gilbert, Seth; Lynch, Nancy Ann

    2012-01-01

    Almost twelve years ago, in 2000, Eric Brewer introduced the idea that there is a fundamental trade-off between consistency, availability, and partition tolerance. This trade-off, which has become known as the CAP Theorem, has been widely discussed ever since. In this paper, we review the CAP Theorem and situate it within the broader context of distributed computing theory. We then discuss the practical implications of the CAP Theorem, and explore some general techniques for coping with the i...

  3. Positron emitter labeled enzyme inhibitors

    International Nuclear Information System (INIS)

    This invention involves a new strategy for imagining and mapping enzyme activity in the living human and animal body using positron emitter-labeled suicide enzyme inactivators or inhibitors which become covalently bound to the enzyme as a result of enzymatic catalysis. Two such suicide inactivators for monoamine oxidase have been labeled with carbon-11 and used to map the enzyme subtypes in the living human and animal body using PET. By using positron emission tomography to image the distribution of radioactivity produced by the body penetrating radiation emitted by carbon-11, a map of functionally active monoamine oxidase activity is obtained. Clorgyline and L-deprenyl are suicide enzyme inhibitors and irreversibly inhibit monoamine oxidase. When these inhibitors are labeled with carbon-11 they provide selective probes for monoamine oxidase localization and reactivity in vivo using positron emission tomography

  4. Low Emittance Electron Beam Studies

    Energy Technology Data Exchange (ETDEWEB)

    Tikhoplav, Rodion

    2006-04-01

    We have studied the properties of a low emittance electron beam produced by laser pulses incident onto an rf gun photocathode. The experiments were carried out at the A0 photoinjector at Fermilab. Such beam studies are necessary for fixing the design of new Linear Colliders as well as for the development of Free Electron Lasers. An overview of the A0 photoinjector is given in Chapter 1. In Chapter 2 we describe the A0 photoinjector laser system. A stable laser system is imperative for reliable photoinjector operation. After the recent upgrade, we have been able to reach a new level of stability in the pulse-to-pulse fluctuations of the pulse amplitude, and of the temporal and transverse profiles. In Chapter 3 we present a study of transverse emittance versus the shape of the photo-cathode drive-laser pulse. For that purpose a special temporal profile laser shaping device called a pulse-stacker was developed. In Chapter 4 we discuss longitudinal beam dynamics studies using a two macro-particle bunch; this technique is helpful in analyzing pulse compression in the magnetic chicane, as well as velocity bunching effects in the rf-gun and the 9-cell accelerating cavity. In Chapter 5 we introduce a proposal for laser acceleration of electrons. We have developed a laser functioning on the TEM*{sub 01} mode, a mode with a longitudinal electric field component which is suitable for such a process. Using this technique at energies above 40 MeV, one would be able to observe laser-based acceleration.

  5. Novel Multipin Electrode Cap System for Dry Electroencephalography.

    Science.gov (United States)

    Fiedler, P; Pedrosa, P; Griebel, S; Fonseca, C; Vaz, F; Supriyanto, E; Zanow, F; Haueisen, J

    2015-09-01

    Current usage of electroencephalography (EEG) is limited to laboratory environments. Self-application of a multichannel wet EEG caps is practically impossible, since the application of state-of-the-art wet EEG sensors requires trained laboratory staff. We propose a novel EEG cap system with multipin dry electrodes overcoming this problem. We describe the design of a novel 24-pin dry electrode made from polyurethane and coated with Ag/AgCl. A textile cap system holds 97 of these dry electrodes. An EEG study with 20 volunteers compares the 97-channel dry EEG cap with a conventional 128-channel wet EEG cap for resting state EEG, alpha activity, eye blink artifacts and checkerboard pattern reversal visual evoked potentials. All volunteers report a good cap fit and good wearing comfort. Average impedances are below 150 kΩ for 92 out of 97 dry electrodes, enabling recording with standard EEG amplifiers. No significant differences are observed between wet and dry power spectral densities for all EEG bands. No significant differences are observed between the wet and dry global field power time courses of visual evoked potentials. The 2D interpolated topographic maps show significant differences of 3.52 and 0.44% of the map areas for the N75 and N145 VEP components, respectively. For the P100 component, no significant differences are observed. Dry multipin electrodes integrated in a textile EEG cap overcome the principle limitations of wet electrodes, allow rapid application of EEG multichannel caps by non-trained persons, and thus enable new fields of application for multichannel EEG acquisition. PMID:25998854

  6. Variable Emittance Electrochromics Using Ionic Electrolytes and Low Solar Absorptance Coatings

    Science.gov (United States)

    Chandrasekhar, Prasanna

    2011-01-01

    One of the last remaining technical hurdles with variable emittance devices or skins based on conducting polymer electrochromics is the high solar absorptance of their top surfaces. This high solar absorptance causes overheating of the skin when facing the Sun in space. Existing technologies such as mechanical louvers or loop heat pipes are virtually inapplicable to micro (coatings lower the solar absorption to Alpha(s) of between 0.30 and 0.46. Coupled with the emittance properties of the variable emittance skins, this lowers the surface temperature of the skins facing the Sun to between 30 and 60 C, which is much lower than previous results of 100 C, and is well within acceptable satellite operations ranges. The performance of this technology is better than that of current new technologies such as microelectromechanical systems (MEMS), electrostatics, and electrophoretics, especially in applications involving micro and nano spacecraft. The coatings are deposited inside a high vacuum, layering multiple coatings onto the top surfaces of variable emittance skins. They are completely transparent in the entire relevant infrared region (about 2 to 45 microns), but highly reflective in the visible-NIR (near infrared) region of relevance to solar absorptance.

  7. Multinozzle Emitter Arrays for Nanoelectrospray Mass Spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Mao, Pan; Wang, Hung-Ta; Yang, Peidong; Wang, Daojing

    2011-06-16

    Mass spectrometry (MS) is the enabling technology for proteomics and metabolomics. However, dramatic improvements in both sensitivity and throughput are still required to achieve routine MS-based single cell proteomics and metabolomics. Here, we report the silicon-based monolithic multinozzle emitter array (MEA), and demonstrate its proof-of-principle applications in high-sensitivity and high-throughput nanoelectrospray mass spectrometry. Our MEA consists of 96 identical 10-nozzle emitters in a circular array on a 3-inch silicon chip. The geometry and configuration of the emitters, the dimension and number of the nozzles, and the micropillar arrays embedded in the main channel, can be systematically and precisely controlled during the microfabrication process. Combining electrostatic simulation and experimental testing, we demonstrated that sharpened-end geometry at the stem of the individual multinozzle emitter significantly enhanced the electric fields at its protruding nozzle tips, enabling sequential nanoelectrospray for the high-density emitter array. We showed that electrospray current of the multinozzle emitter at a given total flow rate was approximately proportional to the square root of the number of its spraying-nozzles, suggesting the capability of high MS sensitivity for multinozzle emitters. Using a conventional Z-spray mass spectrometer, we demonstrated reproducible MS detection of peptides and proteins for serial MEA emitters, achieving sensitivity and stability comparable to the commercial capillary emitters. Our robust silicon-based MEA chip opens up the possibility of a fully-integrated microfluidic system for ultrahigh-sensitivity and ultrahigh-throughput proteomics and metabolomics.

  8. Performance comparisons of low emittance lattices

    International Nuclear Information System (INIS)

    In this paper, the results of a performance analysis of several low emittance electron storage ring lattices provided by various members of the Lattice Working Group are presented. Altogether, four lattices were investigated. There are two different functions being considered for the low beam emittance rings discussed here. The first is to serve as a Damping Ring (DR), i.e., to provide the emittance damping required for a high energy linear collider. The second is to provide beams for a short wavelength Free Electron Laser (FEL), which is envisioned to operate in the wavelength region near 40 A

  9. Alpha-cyclodextrins reversibly capped with disulfide bonds

    Czech Academy of Sciences Publication Activity Database

    Kumprecht, Lukáš; Buděšínský, Miloš; Bouř, Petr; Kraus, Tomáš

    2010-01-01

    Roč. 34, č. 10 (2010), s. 2254-2260. ISSN 1144-0546 R&D Projects: GA AV ČR IAA400550810 Institutional research plan: CEZ:AV0Z40550506 Keywords : cyclodextrin s * disulfide bond * dynamic covalent bond Subject RIV: CC - Organic Chemistry Impact factor: 2.631, year: 2010

  10. Low emittance upgrade for CANDLE project

    CERN Document Server

    Zanyan, G S

    2015-01-01

    To improve the performance of CANDLE synchrotron light source and stay competitive with recently proposed low emittance upgrade programs in the world we have developed new low emittance lattices for CANDLE booster and storage ring. These lattices have been designed taking into account the new developments in magnet fabrication technology and the multi-bend achromat concept. The main design considerations, the linear and non-linear beam dynamics aspects of the modified lattices are presented.

  11. Remote Optical Detection of Alpha Radiation

    International Nuclear Information System (INIS)

    Alpha emitting radiation sources are typically hard to detect with conventional detectors due to the short range of alpha particles in the air. However, previous studies have shown that remote detection of alpha radiation is possible by measuring the ionization-induced fluorescence of air molecules. The alpha-induced ultraviolet (UV) light is mainly emitted by molecular nitrogen and its fluorescence properties are well known. The benefit of this method is the long range of UV photons in the air. Secondly, the detection is possible also under a strong beta and gamma radiation backgrounds as they do not cause localized molecular excitation. In this work, the optical detection was studied using two different detection schemes; spectral separation of fluorescence from the background lighting and coincidence detection of UV photons originating from a single radiative decay event. Our spectrally integrated measurements have shown that one alpha decay event yields up to 400 fluorescence photons in the air and all these UV photons are induced in a 5 ns time-window. On the other hand, the probability of a background coincidence event in 5 ns scale is very rare compared to the number of background photons. This information can be applied in fluorescence coincidence filtering to discriminate the alpha radiation initiated fluorescence signal from much more intense background lighting. A device called HAUVA (Handheld Alpha UV Application) was built during this work for demonstration purposes. HAUVA utilizes spectral filtering and it is designed to detect alpha emitters from a distance of about 40 cm. Using specially selected room lighting, the device is able to separate 1 kBq alpha emitter from the background lighting with 1 second integration time. (author)

  12. Polar caps in the presence of an induction field

    CERN Document Server

    Jones, P B

    2015-01-01

    Following the early paper of Goldreich & Julian (1969), polar-cap models have usually assumed that the closed sector of a pulsar magnetosphere corotates with the neutron star. Recent work by Melrose & Yuen has been a reminder that in an oblique rotator, the induction field arising from the time-varying magnetic flux density cannot be completely screened. The principal consequence is that the plasma does not corotate with the star. Here it is shown that the physics of the polar cap is not changed at the altitudes of the radio emission source. But the presence of a plasma drift velocity in the corotating frame of reference does provide a mechanism whereby the net charge of the star can be maintained within a stable band of values. It also shows directly how electron injection and acceleration occur in the outer gap of the magnetosphere. It is consistent with radio-loud pulsars in the Fermi LAT catalogue of gamma-emitters all having positive polar-cap charge density.

  13. Radiological hazards of alpha-contaminated waste

    International Nuclear Information System (INIS)

    The radiological hazards of alpha-contaminated wastes are discussed in this overview in terms of two components of hazard: radiobiological hazard, and radioecological hazard. Radiobiological hazard refers to human uptake of alpha-emitters by inhalation and ingestion, and the resultant dose to critical organs of the body. Radioecological hazard refers to the processes of release from buried wastes, transport in the environment, and translocation to man through the food chain. Besides detailing the sources and magnitude of hazards, this brief review identifies the uncertainties in their estimation, and implications for the regulatory process

  14. A low-emittance lattice for SPEAR

    Science.gov (United States)

    Safranek, J.; Wiedemann, H.

    1992-08-01

    The design and implementation of a low emittance lattice for the SPEAR storage ring including measurements of the performance of the lattice are presented [J. Safranek, Ph.D. thesis, Stanford University, 1991]. The low emittance lattice is designed to optimize the performance of SPEAR as a synchrotron radiation source while keeping SPEAR hardware changes at a minimum. The horizontal emittance of the electron beam in the low emittance lattice is reduced by a factor of 4 from the previous lattice. This reduces the typical horizontal source size and divergence of the photon beams by a factor of 2 each and increases the photon beam brightness. At 3 GeV the horizontal emittance is 129π nm rad, which makes the low emittance lattice the lowest emittance, running synchrotron radiation source in the world in the 1.5 to 4.0 GeV energy range for the emittance scaled to 3 GeV. The measured vertical emittance was reduced to half that typically seen at SPEAR in the past. The brightness of the photon beams was further increased by reducing βy at the insertion devices to 1.1 m and reducing the energy dispersion at the insertion devices by more than a factor of 2 on average. The horizontal dispersion at the rf cavities was reduced by a factor of nearly 4 which gives much less problems with synchrobetatron resonances. The dynamic and physical apertures of the lattice are large, giving long beam lifetimes and easy injection of electrons. The measurements of the linear optics and intensity dependent phenomena gave reasonable agreement with the design. The overall performance of the machine was very good. Injection rates of 10 to 20 mA/min and larger were achieved routinely, and 100 mA total current was stored. Repeated ramping of stored beam from the injection energy of 2.3 GeV to the running energy of 3.0 GeV was achieved with very little beam loss. This low emittance configuration is expected to be the operating configuration for SPEAR starting in January 1992.

  15. OPAL detector end-cap

    CERN Multimedia

    1988-01-01

    An end-cap of the OPAL detector with its electromagnetic calorimeter. The calorimeter consists of 566 Cherenkov lead glass counters and weighs 10 tonnes. The OPAL detector ran on the LEP accelerator between 1989 and 2000.

  16. ATLAS - End-Cap calorimeter

    CERN Multimedia

    2006-01-01

    The End-cap calorimeter was moved with the help of the rails and this calorimeter will measure the energy of particles close to the beam axis when protons collide. Cooling is important for maximum detector efficiency.

  17. Researchers dodge UK migration cap

    Science.gov (United States)

    Dacey, James

    2011-03-01

    Research scientists are among those to be prioritized under the UK government's new immigration rules that will impose an annual cap on the number of work visas issued to those from outside the European Union (EU).

  18. Genetics Home Reference: cap myopathy

    Science.gov (United States)

    ... or a spine that curves to the side ( scoliosis ). The name cap myopathy comes from characteristic abnormal ... health conditions: Diagnostic Tests Drug Therapy Surgery and Rehabilitation Genetic Counseling Palliative Care Related Information How are ...

  19. Alpha fetoprotein

    Science.gov (United States)

    Fetal alpha globulin; AFP ... Greater than normal levels of AFP may be due to: Cancer in testes , ovaries, biliary (liver secretion) tract, stomach, or pancreas Cirrhosis of the liver Liver cancer ...

  20. ETAII 6 MEV PEPPERPOT EMITTANCE MEASUREMENT

    Energy Technology Data Exchange (ETDEWEB)

    Paul, A C; Richardson, R; Weir, J

    2004-10-18

    We measured the beam emittance at the ETAII accelerator using a pepper-pot diagnostic at nominal parameters of 6 MeV and 2000 Amperes. During the coarse of these experiments, a ''new tune'' was introduced which significantly improved the beam quality. The source of a background pedestal was investigated and eliminated. The measured ''new tune'' emittance is {var_epsilon}= 8.05 {plus_minus} 0. 53 cm - mr or a normalized emittance of {var_epsilon}{sub n} = 943 {plus_minus} 63 mm - mr In 1990 the ETAII programmatic emphasis was on free electron lasers and the paramount parameter was whole beam brightness. The published brightness for ETAII after its first major rebuild was J = 1 - 3 x 10{sup 8} A/(m - rad){sup 2} at a current and energy of 1000-1400 Amperes and 2.5 MeV. The average normalized emittance derived from table 2 of that report is 864 mm-mr corresponding to a real emittance of 14.8 cm-mr.

  1. Diamond-based single-photon emitters

    International Nuclear Information System (INIS)

    The exploitation of emerging quantum technologies requires efficient fabrication of key building blocks. Sources of single photons are extremely important across many applications as they can serve as vectors for quantum information-thereby allowing long-range (perhaps even global-scale) quantum states to be made and manipulated for tasks such as quantum communication or distributed quantum computation. At the single-emitter level, quantum sources also afford new possibilities in terms of nanoscopy and bio-marking. Color centers in diamond are prominent candidates to generate and manipulate quantum states of light, as they are a photostable solid-state source of single photons at room temperature. In this review, we discuss the state of the art of diamond-based single-photon emitters and highlight their fabrication methodologies. We present the experimental techniques used to characterize the quantum emitters and discuss their photophysical properties. We outline a number of applications including quantum key distribution, bio-marking and sub-diffraction imaging, where diamond-based single emitters are playing a crucial role. We conclude with a discussion of the main challenges and perspectives for employing diamond emitters in quantum information processing.

  2. Measuring emittance using beam position monitors

    International Nuclear Information System (INIS)

    The Los Alamos Advanced Free Electron Laser uses a high charge (greater than InC), low emittance (normalized rams emittance less than 5π mm mrad) photoinjector driven accelerator. The high brightness achieved is due, in large part, to the rapid acceleration of the electrons to relativistic velocities. As a result, the beam does not have time to thermalize its distribution and its universe profile is, in general, non-Gaussian. This, coupled with the very high brightness, makes it difficult to measure the transverse emittance. Techniques used must be able to withstand the rigors of very intense electron beams, and not be reliant on Gaussian assumptions. Beam position monitors are ideal for this. They are not susceptible to beam damage, and it has been shown previously that they can be used to measure the transverse emittance of a beam with a Gaussian profile. However, this Gaussian restriction is not necessary and, in fact, a transverse emittance measurement using beam position monitors is independent of the beam's distribution

  3. Integrated photonic crystal selective emitter for thermophotovoltaics

    Science.gov (United States)

    Zhou, Zhiguang; Yehia, Omar; Bermel, Peter

    2016-01-01

    Converting blackbody thermal radiation to electricity via thermophotovoltaics (TPV) is inherently inefficient. Photon recycling using cold-side filters offers potentially improved performance but requires extremely close spacing between the thermal emitter and the receiver, namely a high view factor. Here, we propose an alternative approach for thermal energy conversion, the use of an integrated photonic crystal selective emitter (IPSE), which combines two-dimensional photonic crystal selective emitters and filters into a single device. Finite difference time domain and current transport simulations show that IPSEs can significantly suppress sub-bandgap photons. This increases heat-to-electricity conversion for photonic crystal based emitters from 35.2 up to 41.8% at 1573 K for a GaSb photovoltaic (PV) diode with matched bandgaps of 0.7 eV. The physical basis of this enhancement is a shift from a perturbative to a nonperturbative regime, which maximized photon recycling. Furthermore, combining IPSEs with nonconductive optical waveguides eliminates a key difficulty associated with TPV: the need for precise alignment between the hot selective emitter and cool PV diode. The physical effects of both the IPSE and waveguide can be quantified in terms of an extension of the concept of an effective view factor.

  4. Variable emittance behavior of smart radiative coating

    Science.gov (United States)

    Guo, Li; Fan, Desong; Li, Qiang

    2016-02-01

    Smart radiative coating on yttria stabilized zirconia (YSZ) substrate was prepared by the sol-gel La{}1-xSr x MnO3 (x = 0.125, 0.175 and 0.2) nanoparticles and the binder composed of terpineol and ethyl cellulose. The crystallized structure, grain size, chemical compositions, magnetization and the surface morphology were characterized. The thermal radiative properties of coating in the infrared range was evaluated from infrared reflectance spectra at various temperatures. A single perovskite structure is detected in sol-gel nanoparticles with size 200 nm. Magnetization measurement reveals that room temperature phase transition samples can be obtained by appropriate Sr substitution. The influence of surface conditions and sintering temperature on the emittance of coating was observed. For rough coatings with root-mean-square roughness 640 nm (x = 0.125) and 800 nm (x = 0.175) , its emittance increment is 0.24 and 0.26 in in the temperature range of 173-373 K. Increasing sintering temperature to 1673 K, coating emittance variation improves to 0.3 and 0.302 respectively. After mechanical polishing treatment, the emittance increment of coatings are enhanced to 0.31 and 0.3, respectively. The results suggested that the emittance variation can be enhanced by reducing surface roughness and increasing sintering temperature of coating.

  5. The island of alpha activity close to the double magic nucleus 100Sn

    International Nuclear Information System (INIS)

    Up to now, 14 alpha emitters have been identified among the neutrondeficient isotopes of Te, I, Xe and Cs. None of the nine formulae of 1975 mass predictions can reproduce the Q-values of all these alpha emitters. Nevertheless, one can say that some good estimates are obtained by using the masses given by: Myers; Groote-Hilf-Takahashi, Liran Zeldes; Jaenecke-Eynon and Jaenecke. If the Q-value is known, our semiempirical formula, based on the fission theory of alpha decay, allow to obtain the best estimates of the partial life-times. This relationship is used to predict new alpha emitters with atomic numbers Z = 52-61. (authors)

  6. Performance comparisons of low emittance lattices

    International Nuclear Information System (INIS)

    The results of a performance analysis of four low emittance electron storage ring lattices provided to the authors by various members of the Lattice Working Group is presented. Altogether, four lattices were investigated. The beam energies of the four lattices are, respectively, 1.1, 2, 3, 4 GeV). A brief summary of the lattice parameters relevant to this study is given. The performance issues studied include an estimation of the longitudinal emittance expected for each lattice based on the effects of the longitudinal microwave instability, an estimation of the transverse emittance growth of the (required) dense bunches under the influence of intrabeam scattering (IBS), and an estimate of the Touschek lifetime. The analysis described here has been carried out with the LBL accelerator physics code ZAP

  7. Optimized aperiodic highly directional narrowband infrared emitters

    Science.gov (United States)

    Granier, Christopher H.; Afzal, Francis O.; Min, Changjun; Dowling, Jonathan P.; Veronis, Georgios

    2014-09-01

    Bulk thermal emittance sources possess incoherent, isotropic, and broadband radiation spectra that vary from material to material. However, these radiation spectra can be drastically altered by modifying the geometry of the structures. In particular, several approaches have been proposed to achieve narrowband, highly directional thermal emittance based on photonic crystals, gratings, textured metal surfaces, metamaterials, and shock waves propagating through a crystal. Here we present optimized aperiodic structures for use as narrowband, highly directional thermal infrared emitters for both TE and TM polarizations. One-dimensional layered structures without texturing are preferable to more complex two- and three-dimensional structures because of the relative ease and low cost of fabrication. These aperiodic multilayer structures designed with alternating layers of silicon and silica on top of a semi-infinite tungsten substrate exhibit extremely high emittance peaked around the wavelength at which the structures are optimized. Structures were designed by a genetic optimization algorithm coupled to a transfer matrix code which computed thermal emittance. First, we investigate the properties of the genetic-algorithm optimized aperiodic structures and compare them to a previously proposed resonant cavity design. Second, we investigate a structure optimized to operate at the Wien wavelength corresponding to a near-maximum operating temperature for the materials used in the aperiodic structure. Finally, we present a structure that exhibits nearly monochromatic and highly directional emittance for both TE and TM polarizations at the frequency of one of the molecular resonances of carbon monoxide (CO); hence, the design is suitable for a detector of CO via absorption spectroscopy.

  8. Creation of polar cap patches

    Science.gov (United States)

    Hosokawa, K.; Taguchi, S.; Ogawa, Y.

    2014-12-01

    Polar cap patches, which are islands of enhanced plasma density drifting anti-sunward, are one of the outstanding phenomena in the polar cap F region ionosphere. In the last decade, data from all-sky airglow imagers have been extensively used for better understanding the propagation of patches in the central polar cap region. But still, it has been rather difficult to capture the birth of patches in their generation region near the dayside cusp, because, in most places, the dayside part of the polar cap ionosphere is sunlit even in winter. In Longyearbyen (78.1N, 15.5E), Norway, however, optical observations are possible near the dayside cusp region in a limited period around the winter solstice. This enables us to directly image how polar cap patches are born in the cusp. In this paper, we present a few intervals of daytime optical observations, during which polar cap patches were generated within the field-of-view of an all-sky imager in Longyearbyen. During all the intervals studied here, we identified several signatures of poleward moving auroral forms (PMAF) in the equatorward half of the field-of-view, which are known as ionospheric manifestations of dayside reconnection. Interestingly, patches were directly produced from such poleward moving auroral signatures and propagated poleward along the anti-sunward convection near the cusp. In the literature, Lorentzen et al. (2012) first reported such a direct production of patches from PMAFs. During the current observations, however, we succeeded in tracking the propagation of patches until they reached the poleward edge of the field-of-view of the imager. This confirms that the faint airglow structures produced from PMAFs were actually transported for a long distance towards the central polar cap area; thus, polar cap patches were produced. From this set of observations, we suggest that polar cap patches during moderately disturbed conditions (i.e, non-storm time conditions) can be directly produced by the

  9. Coupling single emitters to quantum plasmonic circuits

    CERN Document Server

    Huck, Alexander

    2016-01-01

    In recent years the controlled coupling of single photon emitters to propagating surface plasmons has been intensely studied, which is fueled by the prospect of a giant photonic non-linearity on a nano-scaled platform. In this article we will review the recent progress on coupling single emitters to nano-wires towards the construction of a new platform for strong light-matter interaction. The control over such a platform might open new doors for quantum information processing and quantum sensing at the nanoscale, and for the study of fundamental physics in the ultra-strong coupling regime.

  10. Quadrupole Transfer Function for Emittance Measurement

    CERN Document Server

    Cameron, Peter; Jansson, Andreas; Tan, Cheng-Yang

    2008-01-01

    Historically the use of the quadrupole moment measurement has been impeded by the requirement for large dynamic range, as well as measurement sensitivity to beam position. We investigate the use of the transfer function technique [1-3] in combination with the sensitivity and 160dB revolution line rejection of the direct diode detection analog front end [4] to open the possibility of an emittance diagnostic that may be implemented without operational complication, quasi- parasitic to the operation of existing tune measurement systems. Such a diagnostic would be particularly useful as an emittance monitor during acceleration ramp development in machines like RHIC and the LHC.

  11. Studies of emittance growth in the ATF

    International Nuclear Information System (INIS)

    Several different mechanisms of emittance growth in the Accelerator Test Facility (ATF) at KEK are investigated: the author calculates rise times of the fast beam-ion instability for the damping ring (DR), and discusses the emittance growth caused by coherent synchrotron radiation in the beam-transport line (BT), the effect of quadrupole wake fields in the injector linac, and, finally, a single-bunch head-tail ion effect that can occur in both the DR and the BT. A first attempt to measure the quadrupole wake on the real machine is also reported

  12. Research on Radar Emitter Attribute Recognition Method

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In order to solve emitter recognition problems in a practical reconnaissance environment, attribute mathematics is introduced. The basic concepts and theory of attribute set and attribute measure are described in detail. A new attribute recognition method based on attribute measure is presented in this paper. Application example is given, which demonstrates this new method is accurate and effective. Moreover, computer simulation for recognizing the emitter purpose is selected, and compared with classical statistical pattern recognition through simulation. The excellent experimental results demonstrate that this is a brand-new attribute recognition method as compared to existing statistical pattern recognition techniques.

  13. Crystal structure of Bacillus anthracis transpeptidase enzyme CapD.

    Energy Technology Data Exchange (ETDEWEB)

    Wu, R.; Richter, S.; Zhang, R.; Anderson, V. J.; Missiakas, D.; Joachimiak, A.; Biosciences Division; Univ. of Chicago

    2009-09-04

    Bacillus anthracis elaborates a poly-{gamma}-d-glutamic acid capsule that protects bacilli from phagocytic killing during infection. The enzyme CapD generates amide bonds with peptidoglycan cross-bridges to anchor capsular material within the cell wall envelope of B. anthracis. The capsular biosynthetic pathway is essential for virulence during anthrax infections and can be targeted for anti-infective inhibition with small molecules. Here, we present the crystal structures of the {gamma}-glutamyltranspeptidase CapD with and without {alpha}-l-Glu-l-Glu dipeptide, a non-hydrolyzable analog of poly-{gamma}-d-glutamic acid, in the active site. Purified CapD displays transpeptidation activity in vitro, and its structure reveals an active site broadly accessible for poly-{gamma}-glutamate binding and processing. Using structural and biochemical information, we derive a mechanistic model for CapD catalysis whereby Pro{sup 427}, Gly{sup 428}, and Gly{sup 429} activate the catalytic residue of the enzyme, Thr{sup 352}, and stabilize an oxyanion hole via main chain amide hydrogen bonds.

  14. The alpha immunotherapy - A successful solution in cancer treatment

    International Nuclear Information System (INIS)

    Full text: Radiation has been used in cancer therapy for many years. While, in the past the treatment involved mainly use of relatively low energy beta-emitters, more recently it was shown that isotopes emitting alpha particles have been more effective and selective against blood-borne cancers, widespread tumors and residual cells remaining after surgical intervention. This study shows that radioimmunotherapy (RIT) with α emitters may be therapeutically more effective than RIT with conventional β emitters. In the process of designing and developing the radioimmunotherapy procedures, the selection of the isotope is a major factor. This selection depends on a number of criteria and parameters, affecting usefulness and feasibility. Usefulness is directly related to the radiological performance of the ionising radiation in relation to tissue and its morphology, with a major distinction between the effects of alpha and beta-particles. Usefulness is also related to the pharmacodynamic performance of the isotope-carrier (e.g. antibody) complex, where the proper choice of isotope radiodecay half-life is essential. Feasibility depends on availability of the components in the isotope-ligand-carrier complex, and also on convenience and safety aspects in the preparation and the handling of the materials as well as in their application in patients. Alpha immunotherapy is based on emission of alpha particles by radionuclides. Due to its short physical t1/2, 213Bi appears to be especially suitable for use in conjunction with fast-clearing fragments; its 440-keV α emission also can be used for quantitation by external scintigraphy. Bismuth-213, a short-lived alpha particle emitting radionuclide, is generated from the decay of 225Ac, which has a half-life of 10 days. The development of a clinical 225Ac/213Bi generator and the preparation of a 213Bi radiolabeled antibody for radioimmunotherapy of leukemia is reported. Alpha emitting radionuclides are amongst the most promising

  15. $\\alpha_s$ review (2016)

    CERN Document Server

    d'Enterria, David

    2016-01-01

    The current world-average of the strong coupling at the Z pole mass, $\\alpha_s(m^2_{Z}) = 0.1181 \\pm 0.0013$, is obtained from a comparison of perturbative QCD calculations computed, at least, at next-to-next-to-leading-order accuracy, to a set of 6 groups of experimental observables: (i) lattice QCD "data", (ii) $\\tau$ hadronic decays, (iii) proton structure functions, (iv) event shapes and jet rates in $e^+e^-$ collisions, (v) Z boson hadronic decays, and (vi) top-quark cross sections in p-p collisions. In addition, at least 8 other $\\alpha_s$ extractions, usually with a lower level of theoretical and/or experimental precision today, have been proposed: pion, $\\Upsilon$, W hadronic decays; soft and hard fragmentation functions; jets cross sections in pp, e-p and $\\gamma$-p collisions; and photon F$_2$ structure function in $\\gamma\\,\\gamma$ collisions. These 14 $\\alpha_s$ determinations are reviewed, and the perspectives of reduction of their present uncertainties are discussed.

  16. Evaluation of management alternatives for LWR hulls and caps

    International Nuclear Information System (INIS)

    Hulls and caps resulting from the reprocessing of LWR spent fuels represent one of the major sources of alpha-bearing solid waste generated during the nuclear fuel cycle. The Commission of the European Communities has undertaken considerable R and D efforts on the development of advanced treatment and conditioning methods for this type of waste. In view of the encouraging results achieved, the Commission launched a theoretical assessment study on cladding waste management. Six practical or potential schemes were identified and elaborated: direct cementation, decontamination prior to cementation, rolling before cementation, rolling followed by embedding in graphite, compaction, and melting in a cold crucible. The economic aspects of each management option were also investigated. This included the assessment of the plant (treatment, conditioning and interim storage), transport and disposal costs. Further consideration will be required to define the best management option for 'cap' wastes. Transport and disposal costs will also require further analysis from an industrial standpoint

  17. Longitudinal emittance measurements at REX-ISOLDE

    CERN Document Server

    Fraser, M A; Jones, R.M.; Jones, R M; Pasini, M; Posocco, P A; Voulot, D; Wenander, F

    2012-01-01

    We report on measurements of the longitudinal emittance at the Radioactive ion beam EXperiment (REX) at ISOLDE, CERN. The rms longitudinal emittance was measured as 0.34 ± 0.08 π ns keV/u at the output of the RFQ and as 0.36 ± 0.04π ns keV/u in front of the third 7-gap split-ring resonator (7G3) using the three-gradient technique; systematic errors are not included but are estimated at approximately 10%. The 86% emittance was measured a factor of approximately 4.4 times larger than the rms emittance at 1.48 ± 0.2 and 1.55 ± 0.12π ns keV/u at the RFQ and 7G3, respectively. The REX switchyard magnet was used as a spectrometer to analyse the energy spread of the beam as it was manipulated by varying the voltage of the rebuncher (ReB) and 7G3 cavities operating at non-accelerating phases. The transfer matrix for a multi-gap bunching cavity is derived and suitably truncated to allow for the accurate reconstruction of the beam parameters from measurement. The technique for measuring the energy spread was rig...

  18. Emittance in particle and radiation beam techniques

    International Nuclear Information System (INIS)

    The author discusses the important and diverse role of the phase space area - the emittance - in the advanced techniques involving interaction of particle and radiation beams. For undulator radiation from unbunched beams, the radiation phase space is diluted from the coherent phase space of the single electron radiation. When the undulator radiation is used as a light source, it is important to minimize the dilution by decreasing the beam emittance and matching the phase space distributions of the particle and the radiation beams. For optical stochastic cooling, on the other hand, the phase space should be maximally mismatched for efficient cooling. In the case particles are bunched to a length much shorter than the radiation wavelength, the emittance appears as an intensity enhancement factor. In the operation of free electron lasers, the phase space matching becomes doubly important, once as the dilution factor in the initial stage of energy modulation and then as the radiation efficiency factor at the end where the beam is density modulated. The author then discusses some of the beam cooling techniques producing smaller emittances, especially the recent suggestions for relativistic heavy ions in storage rings or electron beams in linacs. These are based on the radiative cooling that occurs when particle beams backscatter powerful laser beams

  19. THz imaging system with the IJJ emitter

    Science.gov (United States)

    Tsujimoto, Manabu; Minami, Hidetoshi; Sawamura, Masashi; Delfanazari, Kaveh; Yamamoto, Takashi; Kashiwagi, Takanari; Kadowaki, Kazuo

    2011-03-01

    The intrinsic Josephson junction (IJJ) emitter consisted of thousands of IJJs uniformly stacked in single crystalline high-Tc superconductor Bi 2 Sr 2 CaCu 2 O8 + δ (Bi-2212) [L. Ozyuzer et al., Science 318, (2007) 1291.] is expected to be a novel source of the continuous terahertz electromagnetic waves (THz-waves). The maximum emission power of tens of microwatts recently obtained with the mesa structure of IJJs seems to be sufficient to make use of the IJJ emitter for some practical applications such as THz imaging. According to the cavity resonance condition, we can control the radiation frequency by changing the geometrical size of the mesa. In this study, we develop the THz imaging system with IJJ emitter. In the presentation, we will show some transparent images of standard specimens obtained by the raster scanning method. Also, we will mention some problems to be solved for the future applications of the IJJ emitter. CREST-JST, WPI-MANA, Strategic Initiative A (University of Tsukuba).

  20. Innovative Field Emitters for High-Voltage Electronic Devices

    Science.gov (United States)

    Sominski, G. G.; Sezonov, V. E.; Taradaev, E. P.; Tumareva, T. A.; Zadiranov, Yu. M.; Kornishin, S. Yu.; Stepanova, A. N.

    2015-12-01

    We describe multitip field emitters with protective coatings, which were developed in Peter the Great St. Petersburg Polytechnic University. The coatings ensure long-term operation of the emitters under high currents and technical vacuum. Innovative multi-layer emitters composed of contacting nanolayers of materials with different work functions are presented as well. The possibility by using the developed emitters in high-voltage electronic devices is demonstrated.

  1. What is so super about super-emitters? Characterizing methane high emitters from natural gas infrastructure

    Science.gov (United States)

    Zavala Araiza, D.; Lyon, D. R.; Alvarez, R.; Harriss, R. C.; Palacios, V.; Hamburg, S.

    2015-12-01

    Methane emissions across the natural gas supply chain are dominated at any one time by a few high-emitters (super-emitters or fat-tail of the distribution), often underrepresented in published datasets used to construct emission inventories. Characterization of high-emitters is essential for improving emission estimates based on atmospheric data (top-down) and emission inventories (bottom-up). The population of high-emitters (e.g. 10-20% of sites that account for 80-90% of the emissions) is temporally and spatially dynamic. As a consequence, it is challenging to design sampling methods and construct estimates that accurately represent their frequency and magnitude of emissions. We present new methods to derive facility-specific emission distribution functions that explicitly integrate the influence of the relatively rare super-emitters. These methods were applied in the Barnett Shale region to construct a custom emission inventory that is then compared to top-down emission estimates for the region. We offer a methodological framework relevant to the design of future sampling campaigns, in which these high-emitters are seamlessly incorporated to representative emissions distributions. This framework can be applied to heterogeneous oil and gas production regions across geographies to obtain accurate regional emission estimates. Additionally, we characterize emissions relative to the fraction of a facility's total methane throughput; an effective metric to identify sites with excess emissions resulting from avoidable operating conditions, such as malfunctioning equipment (defined here as functional super-emitters). This work suggests that identifying functional super-emitters and correcting their avoidable operating conditions would result in significant emission reductions. However, due to their spatiotemporal dynamic behavior, achieving and maintaining uniformly low emissions across the entire population of sites will require mitigation steps (e.g. leak detection

  2. RF Emitter geolocation using PDOA algorithms and UAVs - A strategy from emitter detection to location prediction

    OpenAIRE

    Engebråten, Sondre Andreas

    2015-01-01

    In this thesis, I explored strategies for locating an RF emitter. Expanding on an idea conceived at Norwegian Defence Research Establishment (FFI), of using small, cheap RSS sensors and Unmanned Aerial Vehicles (UAVs) to search for unknown RF emitters. Cheap and simple, will in most cases, mean that some property of the system suffers, compared to more complicated and expensive systems. This thesis attempts to circumvent these issues by using multiple sensors instead of one ...

  3. From Blogs to Bottle Caps

    Science.gov (United States)

    Edinger, Ted

    2012-01-01

    There is a wonderful community of art educators connecting a once-isolated profession through blogging. Art educators around the world are sharing ideas and communicating with their peers through this amazing resource. In this article, the author describes the bottle cap mural at Tulip Grove Elementary School which was inspired by this exchange of…

  4. High-temperature plasmonic thermal emitter for thermophotovotaics

    DEFF Research Database (Denmark)

    Liu, Jingjing; Guler, Urcan; Li, Wei; Kildishev, Alexander V.; Boltasseva, Alexandra; Shalaev, Vladimir M.

    2014-01-01

    We use titanium nitride (TiN) to demonstrate an ultra-thin plasmonic thermal emitter operating at high temperatures (830 K). The spectrally selective emitter exhibits a large emittance at around 2.5 μm and below, and suppresses emission at longer wavelengths....

  5. Direct Alpha Analysis for Forensic Samples (DAAFS)

    International Nuclear Information System (INIS)

    The goal of the DAAFS project is to deliver a field deployable direct alpha sample spectrometry system. This system is designed to rectify current gaps in pure alpha emitting material detection. The system comprises, firstly, an evaluation of multiple innovative methods for rapid on-site sample collection of difficult to detect alpha RN contamination. Secondly, the incorporation of an experimental alpha spectrometry analysis software suite, 'ADAM', is provided for performing the required on-site deconvolution of the complex alpha spectra arising from the direct sample measurement. Software simulation of collected alpha spectra will be handled by 'AASI', which will simulate alpha spectra as a training and analysis verification tool. Thirdly, a Concept of Operations (ConOps) for the system implementation in RN field teams is included. This combination of the swipe methodology, advanced swipe treatment equipment, mobile field laboratories, and the state of the art analysis software suite will provide RN response teams with the capability to identify and rapidly (i.e., hours as opposed to days) quantify low activity and difficult to detect alpha emitters. Further expert analysis support is available to field teams by sharing of raw spectral data via email with off-site laboratories. The proposed system provides the solution to this identified capability gap, specifically, a field-deployable real-time alpha detection system. The system comprises: a non-destructive particle sampler, standardized swipe sampling methods, a self-contained field alpha spectrometry system and an integrated data management/communications tool allowing for real-time raw-data tracking and data sharing. This system also provides responders with the type/quantity of RN material for improved safeguards, forensics, and contamination mitigation applications. (author)

  6. On the Diffuse Lyman-alpha Halo Around Lyman-alpha Emitting Galaxies

    CERN Document Server

    Lake, Ethan; Cen, Renyue; Sadoun, Raphael; Momose, Rieko; Ouchi, Masami

    2015-01-01

    Ly$\\alpha$ photons scattered by neutral hydrogen atoms in the circumgalactic media or produced in the halos of star-forming galaxies are expected to lead to extended Ly$\\alpha$ emission around galaxies. Such low surface brightness Ly$\\alpha$ halos (LAHs) have been detected by stacking Ly$\\alpha$ images of high-redshift star-forming galaxies. We study the origin of LAHs by performing radiative transfer modeling of nine $z=3.1$ Lyman-Alpha Emitters (LAEs) in a high resolution hydrodynamic galaxy formation simulation. We develop a method of computing the mean Ly$\\alpha$ surface brightness profile of each LAE by effectively integrating over many different observing directions. Without adjusting any parameters, our model yields an average Ly$\\alpha$ surface brightness profile in remarkable agreement with observations. We find that observed LAHs can not be accounted for solely by photons originating from the central LAE and scattered to large radii by hydrogen atoms in the circumgalactic gas. Instead, Ly$\\alpha$ em...

  7. The $\\alpha-\\alpha$ fishbone potential revisited

    CERN Document Server

    Day, J P; Elhanafy, M; Smith, E; Woodhouse, R; Papp, Z

    2011-01-01

    The fishbone potential of composite particles simulates the Pauli effect by nonlocal terms. We determine the $\\alpha-\\alpha$ fishbone potential by simultaneously fitting to two-$\\alpha$ resonance energies, experimental phase shifts and three-$\\alpha$ binding energies. We found that essentially a simple gaussian can provide a good description of two-$\\alpha$ and three-$\\alpha$ experimental data without invoking three-body potentials.

  8. Alpha One Foundation

    Science.gov (United States)

    ... Tested Find Support Find Doctor What Is Alpha-1? Alpha-1 Antitrypsin Deficiency (Alpha-1) is a ... results for inhaled augmentation More News Our Number One Goal: Find a cure for Alpha-1. Website ...

  9. Alpha-1 Antitrypsin Test

    Science.gov (United States)

    ... helpful? Also known as: Alpha 1 -antitrypsin; A1AT; AAT Formal name: Alpha 1 Antitrypsin; α1-antitrypsin Related ... know? How is it used? Alpha-1 antitrypsin (AAT) testing is used to help diagnose alpha-1 ...

  10. Alpha spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Krueger, Felix; Wilsenach, Heinrich; Zuber, Kai [IKTP TU-Dresden, Dresden (Germany)

    2014-07-01

    Alpha decays from long living isotopes are one of the limiting backgrounds for experiments searching for rare decays with stringent background constrains, such as neutrinoless double beta decay experiments. It is thus very important to accurately measure the half-lives of these decays, in order to properly model their background contribution. Therefore, it is important to be able to measure half-lives from alpha decays of the order of 1 x 10{sup 15} yr. A measurement of such a long lived decay imposes, however, a series of challenges, where the correct discrimination between background and true signal is critical. There is also a more general interest in such long living half-life measurements, as their value depends crucially on the underlying nuclear model. This work proposes a setup to measure long lived alpha decays, based on the design of the Frisch-Grid ionisation chamber. It is shown that the proposed design provides a good separation of signal and background events. It is also demonstrated that, with pulse shape analysis, it is possible to constrain the source position of the decay, further improving the quality of the data. A discussion of the characterisation of the detector is also presented as well as some results obtained with calibration sources.

  11. Alpha spectroscopy

    International Nuclear Information System (INIS)

    Alpha decays from long living isotopes are one of the limiting backgrounds for experiments searching for rare decays with stringent background constrains, such as neutrinoless double beta decay experiments. It is thus very important to accurately measure the half-lives of these decays, in order to properly model their background contribution. Therefore, it is important to be able to measure half-lives from alpha decays of the order of 1 x 1015 yr. A measurement of such a long lived decay imposes, however, a series of challenges, where the correct discrimination between background and true signal is critical. There is also a more general interest in such long living half-life measurements, as their value depends crucially on the underlying nuclear model. This work proposes a setup to measure long lived alpha decays, based on the design of the Frisch-Grid ionisation chamber. It is shown that the proposed design provides a good separation of signal and background events. It is also demonstrated that, with pulse shape analysis, it is possible to constrain the source position of the decay, further improving the quality of the data. A discussion of the characterisation of the detector is also presented as well as some results obtained with calibration sources.

  12. Tip cap for a rotor blade

    Science.gov (United States)

    Kofel, W. K.; Tuley, E. N.; Gay, C. H., Jr.; Troeger, R. E.; Sterman, A. P. (Inventor)

    1983-01-01

    A replaceable tip cap for attachment to the end of a rotor blade is described. The tip cap includes a plurality of walls defining a compartment which, if desired, can be divided into a plurality of subcompartments. The tip cap can include inlet and outlet holes in walls thereof to permit fluid communication of a cooling fluid there through. Abrasive material can be attached with the radially outer wall of the tip cap.

  13. Small horizontal emittance in the TESLA damping ring

    International Nuclear Information System (INIS)

    The present TESLA damping ring is designed for a normalized horizontal emittance of 8x10-6 m. γ-γ collisions at the TESLA linear collider will benefit from a further decrease of the horizontal emittance. This paper reviews the processes which limit the horizontal emittance in the damping ring. Preliminary estimates on the smallest horizontal emittance for the present TESLA damping ring design as well as an ultimate limit of the emittance reachable with the TESLA damping ring concept will be given

  14. Studying fringe field effect of a field emitter array

    International Nuclear Information System (INIS)

    Field emitter arrays on heavy As-doped Si wafer are studied in vacuum nanoelectronics diode configuration. Different shapes of emitters are considered: cone-shaped point-emitters and cylinder-shaped sharp-edge-emitters are compared. Micro scale field enhancement factor on the edge of cylindrical emitter was calculated via home-developed Matlab application and the results are presented. Two types of anode geometry are proposed: plane anode and spherical anode. Experimental and modelling results of surface electric field distribution are presented. The spherical shape of anode allows higher voltage (and higher field emission current) without destructive arcs risk

  15. Discovery of a Giant Lya Emitter Near the Reionization Epoch

    Energy Technology Data Exchange (ETDEWEB)

    Ouchi, Masami; Ono, Yoshiaki; Egami, Eiichi; Saito, Tomoki; Oguri, Masamune; McCarthy, Patrick J.; Farrah, Duncan; Kashikawa, Nobunari; Momcheva, Ivelina; Shimasaku, Kazuhiro; Nakanishi, Kouichiro; Furusawa, Hisanori; Akiyama, Masayuki; Dunlop, James S.; Mortier, Angela M.J.; Okamura, Sadanori; Hayashi, Masao; Cirasuolo, Michele; Dressler, Alan; Iye, Masanori; Jarvis, Matt.J.

    2008-08-01

    We report the discovery of a giant Ly{alpha} emitter (LAE) with a Spitzer/IRAC counterpart near the reionization epoch at z = 6.595. The giant LAE is found from the extensive 1 deg{sup 2} Subaru narrow-band survey for z = 6.6 LAEs in the Subaru/XMM-Newton Deep Survey (SXDS) field, and subsequently identified by deep spectroscopy of Keck/DEIMOS and Magellan/IMACS. Among our 207 LAE candidates, this LAE is not only the brightest narrow-band object with L(Ly{alpha}) = 3.9 {+-} 0.2 x 10{sup 43} erg s{sup -1} in our survey volume of 10{sup 6} Mpc{sup 3}, but also a spatially extended Ly{alpha} nebula with the largest isophotal area whose major axis is at least {approx_equal} 3-inches. This object is more likely to be a large Ly{alpha} nebula with a size of {approx}> 17-kpc than to be a strongly-lensed galaxy by a foreground object. Our Keck spectrum with medium-high spectral and spatial resolutions suggests that the velocity width is v{sub FWHM} = 251 {+-} 21 km s{sup -1}, and that the line-center velocity changes by {approx_equal} 60 km s{sup -1} in a 10-kpc range. The stellar mass and star-formation rate are estimated to be 0.9-5.0 x 10{sup 10}M{sub {circle_dot}} and > 34 M{sub {circle_dot}}yr{sup -1}, respectively, from the combination of deep optical to infrared images of Subaru, UKIDSS-Ultra Deep Survey, and Spitzer/IRAC. Although the nature of this object is not yet clearly understood, this could be an important object for studying cooling clouds accreting onto a massive halo, or forming-massive galaxies with significant outflows contributing to cosmic reionization and metal enrichment of inter-galactic medium.

  16. Dynamic Modeling of an Evapotranspiration Cap

    Energy Technology Data Exchange (ETDEWEB)

    Jacob J. Jacobson; Steven Piet; Rafael Soto; Gerald Sehlke; Harold Heydt; John Visser

    2005-10-01

    The U.S. Department of Energy is scheduled to design and install hundreds of landfill caps/barriers over the next several decades and these caps will have a design life expectancy of up to 1,000 years. Other landfill caps with 30 year design lifetimes are reaching the end of their original design life; the changes to these caps need to be understood to provide a basis for lifetime extension. Defining the attributes that make a successful cap (one that isolates the waste from the environment) is crucial to these efforts. Because cap systems such as landfill caps are dynamic in nature, it is impossible to understand, monitor, and update lifetime predictions without understanding the dynamics of cap degradation, which is most often due to multiple interdependent factors rather than isolated independent events. In an attempt to understand the dynamics of cap degradation, a computer model using system dynamics is being developed to capture the complex behavior of an evapotranspiration cap. The specific objectives of this project are to capture the dynamic, nonlinear feedback loop structures underlying an evapotranspiration cap and, through computer simulation, gain a better understanding of long-term behavior, influencing factors, and, ultimately, long-term cap performance.

  17. Analyses of hydraulic performance of velocity caps

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Degn Eskesen, Mark Chr.; Buhrkall, Jeppe;

    2014-01-01

    The hydraulic performance of a velocity cap has been investigated. Velocity caps are often used in connection with offshore intakes. CFD (computational fluid dynamics) examined the flow through the cap openings and further down into the intake pipes. This was combined with dimension analyses...

  18. 21 CFR 888.3000 - Bone cap.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Bone cap. 888.3000 Section 888.3000 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ORTHOPEDIC DEVICES Prosthetic Devices § 888.3000 Bone cap. (a) Identification. A bone cap is a...

  19. ATLAS End Cap toroid in upstanding position

    CERN Multimedia

    2005-01-01

    End Cap toroid The ATLAS End Cap toroid weights 240-ton and is 12-m diameter high. The parts of this vacuum vessel had to be integrated and tested so that End Cap Toroid has no leaks. After that it could be cooled down to 80 K.

  20. Dynamic Modeling of an Evapotranspiration Cap

    International Nuclear Information System (INIS)

    The U.S. Department of Energy is scheduled to design and install hundreds of landfill caps/barriers over the next several decades and these caps will have a design life expectancy of up to 1,000 years. Other landfill caps with 30 year design lifetimes are reaching the end of their original design life; the changes to these caps need to be understood to provide a basis for lifetime extension. Defining the attributes that make a successful cap (one that isolates the waste from the environment) is crucial to these efforts. Because cap systems such as landfill caps are dynamic in nature, it is impossible to understand, monitor, and update lifetime predictions without understanding the dynamics of cap degradation, which is most often due to multiple interdependent factors rather than isolated independent events. In an attempt to understand the dynamics of cap degradation, a computer model using system dynamics is being developed to capture the complex behavior of an evapotranspiration cap. The specific objectives of this project are to capture the dynamic, nonlinear feedback loop structures underlying an evapotranspiration cap and, through computer simulation, gain a better understanding of long-term behavior, influencing factors, and, ultimately, long-term cap performance

  1. Alpha-emitting radioisotopes production for radioimmunotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Kwon Soo [Korea Institutet of Radiological and Medical Sciences, Seoul (Korea, Republic of)

    2007-02-15

    This review discusses the production of alpha-particle-emitting radionuclides in radioimmunotherapy. Radioimmunotherapy labeled with alpha-particle is expected to be very useful for the treatment of monocellular cancer (e.g. leukemia) and micrometastasis at an early stage, residual tumor remained in tissues after chemotherapy and tumor resection, due to the high linear energy transfer (LET) and the short path length in biological tissue of alpha particle. Despite of the expected effectiveness of alpha-particle in radioimmunotherapy, its clinical research has not been activated by the several reasons, shortage of a suitable a-particle development and a reliable radionuclide production and supply system, appropriate antibody and chelator development. Among them, the establishment of radionuclide development and supply system is a key factor to make an alpha-immunotherapy more popular in clinical trial. Alpha-emitter can be produced by several methods, natural radionuclides, reactor irradiation, cyclotron irradiation, generator system and elution. Due to the sharply increasing demand of {sup 213}Bi, which is a most promising radionuclide in radioimmunotherapy and now has been produced with reactor, the cyclotron production system should be developed urgently to meet the demand.

  2. An ultracold low emittance electron source

    CERN Document Server

    Xia, G; Murray, A J; Bellan, L; Bertsche, W; Appleby, R B; Mete, O; Chattopadhyay, S

    2014-01-01

    Ultracold atom-based electron sources have recently been proposed as an alternative to the conventional photo-injectors or thermionic electron guns widely used in modern particle accelerators. The advantages of ultracold atom-based electron sources lie in the fact that the electrons extracted from the plasma (created from near threshold photo-ionization of ultracold atoms) have a very low temperature, i.e. down to tens of Kelvin. Extraction of these electrons has the potential for producing very low emittance electron bunches. These features are crucial for the next generation of particle accelerators, including free electron lasers, plasma-based accelerators and future linear colliders. The source also has many potential direct applications, including ultrafast electron diffraction (UED) and electron microscopy, due to its intrinsically high coherence. In this paper, the basic mechanism of ultracold electron beam production is discussed and our new research facility for an ultracold, low emittance electron s...

  3. Emittance growths in resonance crossing at FFAGs

    Energy Technology Data Exchange (ETDEWEB)

    Ng, K.Y.; /Fermilab; Pang, X.; Wang, F.; Wang, X.; Lee, S.Y.; /Indiana U.

    2007-10-01

    Scaling laws of the emittance growth for a beam crossing the 6th-order systematic space-charge resonances and the random-octupole driven 4th-order resonance are obtained by numerical multi-particle simulations. These laws can be important in setting the minimum acceleration rate and maximum tolerable resonance strength for the design of non-scaling fixed-field alternating gradient accelerators.

  4. Phase focusing for finite emittance beams

    International Nuclear Information System (INIS)

    An accelerator is a prime example of a physical system in which a beam of particles absorbs energy continuously from externally imposed electromagnetic fields only by remaining in, or very close to synchronism with the fields. Traveling-wave amplifiers are another example. When the injected beam has finite emittance, deviations from exact synchronism can arise, usually limiting the ultimate energy exchange with the fields, and the ultimate emittance of an accelerated beam. A general theory is provided in this paper for a means of limiting deviations from exact synchronism. This can be achieved by providing a small space-varying detuning from synchronism for a particle near the center of the distribution, thus allowing otherwise nonsynchronous particles brief opportunities to enjoy synchronism, and thus to limit their excursions in phase. To illustrate, an example is given of two-stage cyclotron autoresonance acceleration of a finite emittance beam, with and without detuning in the first stage. Space-varying detuning is shown to provide phase focusing in the first stage, lower phase spread at the entrance of the second stage, and thus higher ultimate energy. copyright 1999 American Institute of Physics

  5. Phase focusing for finite emittance beams

    International Nuclear Information System (INIS)

    An accelerator is a prime example of a physical system in which a beam of particles absorbs energy continuously from externally imposed electromagnetic fields only by remaining in, or very close to synchronism with the fields. Traveling-wave amplifiers are another example. When the injected beam has finite emittance, deviations from exact synchronism can arise, usually limiting the ultimate energy exchange with the fields, and the ultimate emittance of an accelerated beam. A general theory is provided in this paper for a means of limiting deviations from exact synchronism. This can be achieved by providing a small space-varying detuning from synchronism for a particle near the center of the distribution, thus allowing otherwise nonsynchronous particles brief opportunities to enjoy synchronism, and thus to limit their excursions in phase. To illustrate, an example is given of two-stage cyclotron autoresonance acceleration of a finite emittance beam, with and without detuning in the first stage. Space-varying detuning is shown to provide phase focusing in the first stage, lower phase spread at the entrance of the second stage, and thus higher ultimate energy

  6. Sectional and projectional emittance measurements a

    International Nuclear Information System (INIS)

    For many applications of ion sources the quality of the generated ion beam plays an increasingly important role. Ion sources consist of the plasma generator and the extraction system. Both parts can, due to high ion temperature or various aberrations, contribute to a degrading of the beam quality. Though the beam quality is determined by many more factors, the transverse motion of the particles certainly is one of the important parameters. Knowledge of it can be obtained by an emittance measurement. This is best done in a four-dimensional phase space, yielding a density distribution as function of the transverse spatial and momentum coordinates. Often, however, due to practical considerations, only two dimensions of the four-dimensional open-quote open-quote trace space close-quote close-quote are being measured. This two-dimensional data can be obtained as a section or as a projection of the four-dimensional trace space, where both methods have their merits. Projectional emittance measurements can usually be performed much easier and quicker, but by the projection of the four-dimensional space onto a two-dimensional plane information is lost. And although not all the particles of the beam are represented in a section of trace space, here aberrative distortions of the emittance can be seen most clearly and allow an easier comparison to numerically obtained data. The advantages and disadvantages of both methods are discussed. Numerical and experimental examples are presented. copyright 1996 American Institute of Physics

  7. Emittance problems in Tau-charm factories

    International Nuclear Information System (INIS)

    Tau-charm factory (TCF) was proposed by J. Kirkby for high precision studies of τ-leptons, τ-neutrinos and charmed particles. A number of requirements for TCF physics put hard constraints on the machine. The peak luminosity must be around the τ-lepton production threshold energy of E≅2 GeV and higher than 1033 cm-2s-1. TCF must provide a high average luminosity and high luminosity must be provided is a wide energy range from E≅1.5∼2.85 GeV. In this report, the TCF lattice requirements and possible solutions were discussed. The lattices with FODO regular cells were considered to be suitable for TCF, although larger longitudinal acceptance at low emittance option is desirable. Additional studies for high emittance option with DBA and TBA regular cells are necessary to overcome small dynamic aperture. The main collider parameters of conventional and monochromatic designs were presented. And it was concluded that TCF should be designed with possibility to work not only with marginal values of emittance, but intermediate too. (M.N.)

  8. Modular low-voltage electron emitters

    International Nuclear Information System (INIS)

    Modular, low-voltage electron emitters simplify electron beam (EB) technology for many industrial uses and for research and development. Modular electron emitters are produced in quantity as sealed systems that are evacuated at the factory, eliminating the need for vacuum pumps at the point of use. A plug-out-plug-in method of replacement facilitates servicing. By using an ultra-thin 6-7 μm titanium foil window, solid-state power supplies, an innovative design to extract and spread the beam (enabling systems to be placed adjacent to each other to extend beam width) and touch-screen computer controls, these modular units combine ease of use and electrical transfer efficiency at voltages that can be varied between 80 kV and 150 kV with beam currents up to 40 mA per 25 cm across the beam window. These new devices have been made in three widths: 5 cm, 25 cm, and 40 cm. Details of the beam construction and illustrations of industrial uses will be presented. Traditional uses in the graphic arts and coatings areas have welcomed this modular technology as well as uses for surface sterilization. Being compact and lightweight (∼15 kg/emitter), these modular beams have been configured around complex shapes to achieve three-dimensional surface curing at high production rates

  9. Traceability and the new CAP

    OpenAIRE

    Maraveyas, Napoleon N.; Doukas, Yannis El.

    2009-01-01

    The Common Agricultural Policy (CAP) was strongly criticized for the food safety crises of the 1990s which included Bovine Spongiform Encephalopathy (BSE), dioxin, foot and mouth disease and swine fever to name a few. Even though the first rules on food safety date from the very early days of the EU, a need was recognized to replace a number of these rules accumulated through the years, whose implementation was difficult to monitor, with a simpler and more comprehensive approach. The result w...

  10. Field emission properties of capped carbon nanotubes doped by alkali metals:a theoretical investigation

    Institute of Scientific and Technical Information of China (English)

    Jin Lei; Fu Hong-Gang; Xie Ying; Yu Hai-Tao

    2012-01-01

    The electronic structures and field emission properties of capped CNT55 systems with or without alkali metal atom adsorption were systematically investigated by density functional theory calculation.The results indicate that the adsorption of alkali metal on the center site of a CNT tip is energetically favorable.In addition,the adsorption energies increase with the introduction of the electric field.The excessive negative charges on CNT tips make electron emittance much easier and result in a decrease in work function.Furthermore,the inducing effect by positively charged alkali metal atoms can be reasonably considered as the dominant reason for the improvement in field emission properties.

  11. Emissivity Tuned Emitter for RTPV Power Sources

    Energy Technology Data Exchange (ETDEWEB)

    Carl M. Stoots; Robert C. O' Brien; Troy M. Howe

    2012-03-01

    Every mission launched by NASA to the outer planets has produced unexpected results. The Voyager I and II, Galileo, and Cassini missions produced images and collected scientific data that totally revolutionized our understanding of the solar system and the formation of the planetary systems. These missions were enabled by the use of nuclear power. Because of the distances from the Sun, electrical power was produced using the radioactive decay of a plutonium isotope. Radioisotopic Thermoelectric Generators (RTGs) used in the past and currently used Multi-Mission RTGs (MMRTGs) provide power for space missions. Unfortunately, RTGs rely on thermocouples to convert heat to electricity and are inherently inefficient ({approx} 3-7% thermal to electric efficiency). A Radioisotope Thermal Photovoltaic (RTPV) power source has the potential to reduce the specific mass of the onboard power supply by increasing the efficiency of thermal to electric conversion. In an RTPV, a radioisotope heats an emitter, which emits light to a photovoltaic (PV) cell, which converts the light into electricity. Developing an emitter tuned to the desired wavelength of the photovoltaic is a key part in increasing overall performance. Researchers at the NASA Glenn Research Center (GRC) have built a Thermal Photovoltaic (TPV) system, that utilizes a simulated General Purpose Heat Source (GPHS) from a MMRTG to heat a tantalum emitter. The GPHS is a block of graphite roughly 10 cm by 10 cm by 5 cm. A fully loaded GPHS produces 250 w of thermal power and weighs 1.6 kgs. The GRC system relies on the GPHS unit radiating at 1200 K to a tantalum emitter that, in turn, radiates light to a GaInAs photo-voltaic cell. The GRC claims system efficiency of conversion of 15%. The specific mass is around 167 kg/kWe. A RTPV power source that utilized a ceramic or ceramic-metal (cermet) matrix would allow for the combination of the heat source, canister, and emitter into one compact unit, and allow variation in size

  12. Monocytes and neutrophils expressing myeloperoxidase occur in fibrous caps and thrombi in unstable coronary plaques

    Directory of Open Access Journals (Sweden)

    Li Ling

    2009-06-01

    Full Text Available Abstract Background Myeloperoxidase (MPO -containing macrophages and neutrophils have been described at sites of plaque rupture. The presence of these cells in precursor lesions to acute rupture (thin cap atheroma, or vulnerable plaque and within thrombi adjacent to ruptures has not been described, nor an association with iron-containing macrophages within unstable plaques. Methods We studied 61 acute ruptures, 15 organizing ruptures, 31 thin cap fibroatheromas, and 28 fibroatheromas from 72 sudden coronary death victims by immunohistochemical and histochemical techniques. Inflammatory cells were typed with anti-CD68 (macrophages, anti-BP-30 (neutrophil bactericidal glycoprotein, and anti-MPO. Iron was localized by Mallory's Prussian blue stain. In selected plaques alpha smooth muscle actin (DAKO, Carpinteria, CA, clone M0851 was performed. Results MPO positive cells were present in 79% of ruptured caps, 28% of thin cap fibroatheroma, and no fibroatheromas; neutrophils were present in 72% of ruptures, 8% of thin cap fibroatheromas, and no fibroatheromas. Iron containing foam cells were present in the caps of 93% of acute ruptures, of 85% of organizing ruptures, 20% of thin cap atheromas, and 10% of fibroatheromas. MPO positive cells were more frequent in occlusive than non-occlusive thrombi adjacent to ruptures (p = .006 and were more numerous in diabetics compared to non-diabetics (p = .002 Conclusion Unstable fibrous caps are more likely to contain MPO-positive cells, neutrophils, and iron-containing macrophages than fibrous caps of stable fibroatheromas. MPO-positive cells in thrombi adjacent to disrupted plaques are associated with occlusive thrombi and are more numerous in diabetic patients.

  13. Polyaniline: a conductive polymer coating for durable nanospray emitters

    Science.gov (United States)

    Maziarz; Lorenz; White; Wood

    2000-07-01

    Despite the tremendous sensitivity and lower sample requirements for nanospray vs. conventional electrospray, metallized nanospray emitters have suffered from one of two problems: low mechanical stability (leading to emitter failure) or lengthy, tedious production methods. Here, we describe a simple alternative to metallized tips using polyaniline (PANI), a synthetic polymer well known for its high conductivity, anticorrosion properties, antistatic properties, and mechanical stability. A simple method for coating borosilicate emitters (1.2 mm o.d.) pulled to fine tapers (4 +/- 1 microm) with water-soluble and xylene-soluble dispersions of conductive polyaniline (which allows for electrical contact at the emitter outlet) is described. The polyaniline-coated emitters show high durability and are resistant to electrical discharge, likely because of the thick (yet optically transparent) coatings; a single emitter can be used over a period of days for multiple samples with no visible indication of the destruction of the polyaniline coating. The optical transparency of the coating also allows the user to visualize the sample plug loaded into the emitter. Examples of nanospray using coatings of the water-soluble and xylene-soluble polyaniline dispersions are given. A comparison of PANI-coated and gold-coated nanospray emitters to conventional electrospray ionization (ESI) show that PANI-coated emitters provide similar enhanced sensitivity that gold-coated emitters exhibit vs. conventional ESI. PMID:10883822

  14. Application of alpha spectrometry to the discovery of new elements by heavy-ion-beam bombardment

    Energy Technology Data Exchange (ETDEWEB)

    Nitschke, J.M.

    1983-05-01

    Starting with polonium in 1898, ..cap alpha..-spectrometry has played a decisive role in the discovery of new, heavy elements. For even-even nuclei, ..cap alpha..-spectra have proved simple to interpret and exhibit systematic trends that allow extrapolation to unknown isotopes. The early discovery of the natural ..cap alpha..-decay series led to the very powerful method of genetically linking the decay of new elements to the well-established ..cap alpha..-emission of daughter and granddaughter nuclei. This technique has been used for all recent discoveries of new elements including Z = 109. Up to mendelevium (Z = 101), thin samples suitable for ..cap alpha..-spectrometry were prepared by chemical methods. With the advent of heavy-ion accelerators new sample preparation methods emerged. These were based on the large momentum transfer associated with heavy-ion reactions, which produced energetic target recoils that, when ejected from the target, could be thermalized in He gas. Subsequent electrical deposition or a He-jet technique yielded samples that were not only thin enough for ..cap alpha..-spectroscopy, but also for ..cap alpha..- and ..beta..-recoil experiments. Many variations of these methods have been developed and are discussed. For the synthesis of element 106 an aerosol-based recoil transport technique was devised. In the most recent experiments, ..cap alpha..-spectrometry has been coupled with the magnetic analysis of the recoils. The time from production to analysis of an isotope has thereby been reduced to 10/sup -6/ s; while it was 10/sup -1/ to 10/sup 0/ s for He-jets and 10/sup 1/ to 10/sup 3/ s for rapid chemical separations. Experiments are now in progress to synthesize super heavy elements (SHE) and to analyze them with these latest techniques. Again, ..cap alpha..-spectrometry will play a major role since the expected signature for the decay of a SHE is a sequence of ..cap alpha..-decays followed by spontaneous fission.

  15. High brightness fiber laser pump sources based on single emitters and multiple single emitters

    Science.gov (United States)

    Scheller, Torsten; Wagner, Lars; Wolf, Jürgen; Bonati, Guido; Dörfel, Falk; Gabler, Thomas

    2008-02-01

    Driven by the potential of the fiber laser market, the development of high brightness pump sources has been pushed during the last years. The main approaches to reach the targets of this market had been the direct coupling of single emitters (SE) on the one hand and the beam shaping of bars and stacks on the other hand, which often causes higher cost per watt. Meanwhile the power of single emitters with 100μm emitter size for direct coupling increased dramatically, which also pushed a new generation of wide stripe emitters or multi emitters (ME) of up to 1000μm emitter size respectively "minibars" with apertures of 3 to 5mm. The advantage of this emitter type compared to traditional bars is it's scalability to power levels of 40W to 60W combined with a small aperture which gives advantages when coupling into a fiber. We show concepts using this multiple single emitters for fiber coupled systems of 25W up to 40W out of a 100μm fiber NA 0.22 with a reasonable optical efficiency. Taking into account a further efficiency optimization and an increase in power of these devices in the near future, the EUR/W ratio pushed by the fiber laser manufacturer will further decrease. Results will be shown as well for higher power pump sources. Additional state of the art tapered fiber bundles for photonic crystal fibers are used to combine 7 (19) pump sources to output powers of 100W (370W) out of a 130μm (250μm) fiber NA 0.6 with nominal 20W per port. Improving those TFB's in the near future and utilizing 40W per pump leg, an output power of even 750W out of 250μm fiber NA 0.6 will be possible. Combined Counter- and Co-Propagated pumping of the fiber will then lead to the first 1kW fiber laser oscillator.

  16. Exoelectron emission studies of irradiated catalysts. [Gamma radiation; Alpha beams

    Energy Technology Data Exchange (ETDEWEB)

    Kuzembaev, K.K.; Sokolskij, D.V.; Burtsev, A.F.; Asubaev, M.K. (AN Kazakhskoj SSR, Alma-Ata. Inst. Organicheskogo Kataliza i Ehlektrokhimii); Kortov, V.S.; Kalentiev, V.A. (Sverdlovskij Politekhnicheskij Inst., Sverdlovsk (USSR))

    1983-01-01

    Catalytic and exoemission properties of ..gamma..-irradiated Pd/SiO/sub 2/ and ..cap alpha..-irradiated Fe/Al catalysts have been found to change sympatically. The character of the active centers formed on the catalyst surface under irradiation is discussed. 9 refs.

  17. Infrared spectral normal emittance/emissivity comparison

    Science.gov (United States)

    Hanssen, L.; Wilthan, B.; Filtz, J.-R.; Hameury, J.; Girard, F.; Battuello, M.; Ishii, J.; Hollandt, J.; Monte, C.

    2016-01-01

    The National Measurement Institutes (NMIs) of the United States, Germany, France, Italy and Japan, have joined in an inter-laboratory comparison of their infrared spectral emittance scales. This action is part of a series of supplementary inter-laboratory comparisons (including thermal conductivity and thermal diffusivity) sponsored by the Consultative Committee on Thermometry (CCT) Task Group on Thermophysical Quantities (TG-ThQ). The objective of this collaborative work is to strengthen the major operative National Measurement Institutes' infrared spectral emittance scales and consequently the consistency of radiative properties measurements carried out worldwide. The comparison has been performed over a spectral range of 2 μm to 14 μm, and a temperature range from 23 °C to 800 °C. Artefacts included in the comparison are potential standards: oxidized Inconel, boron nitride, and silicon carbide. The measurement instrumentation and techniques used for emittance scales are unique for each NMI, including the temperature ranges covered as well as the artefact sizes required. For example, all three common types of spectral instruments are represented: dispersive grating monochromator, Fourier transform and filter-based spectrometers. More than 2000 data points (combinations of material, wavelength and temperature) were compared. Ninety-eight percent (98%) of the data points were in agreement, with differences to weighted mean values less than the expanded uncertainties calculated from the individual NMI uncertainties and uncertainties related to the comparison process. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  18. Emittance growth from transient coherent synchrotron radiation

    International Nuclear Information System (INIS)

    If the energies of individual particles in a bunch change as the bunch traverses a bending system, even if it is achromatic, betatron oscillations can be excited. Consequently, the transverse emittance of the bunch will grow as it moves downstream. Short bunches may be particularly susceptible to emission of coherent synchrotron radiation which can act back on the particles to change their energies and trajectories. Because a bend spans a well-defined length and angle, the bunch-excited wakefield and its effect back on the bunch are inherently transient. We outline a recently developed theory of this effect and apply it to example bending systems

  19. Summary report on transverse emittance preservation

    International Nuclear Information System (INIS)

    During the past years, significant progress has been made in understanding the beam transverse emittance blow-up and its preservation. However, one often finds him-/herself ignorant when he/she tries to explain what was observed in an existing machine or to predict what will happen in a machine under design. There are a number of such examples given in this report. Some of them are even fundamental. These are the challenges. But they are also the directions leading to new achievements. The workshop gladly acknowledged them and promised to work on them

  20. Tolerances for the vertical emittance in damping rings

    International Nuclear Information System (INIS)

    Future damping rings for linear colliders will need to have very small vertical emittances. In the limit of low beam current, the vertical emittance is primarily determined by the vertical dispersion and the betatron coupling. In this paper, the contributions to these effects from random misalignments are calculated and tolerances are derived to limit the vertical emittance with a 95% confidence level. 10 refs., 5 figs

  1. Thermal emittance measurements of a cesium potassium antimonide photocathode

    OpenAIRE

    Bazarov, Ivan; Cultrera, Luca; Bartnik, Adam; Dunham, Bruce; Karkare, Siddharth; Li, Yulin; Liu, Xianghong; Maxson, Jared; Roussel, William

    2011-01-01

    Thermal emittance measurements of a CsK2Sb photocathode at several laser wavelengths are presented. The emittance is obtained with a solenoid scan technique using a high voltage dc photoemission gun. The thermal emittance is 0.56+/-0.03 mm-mrad/mm(rms) at 532 nm wavelength. The results are compared with a simple photoemission model and found to be in a good agreement.

  2. Thermal emittance measurements of a cesium potassium antimonide photocathode

    Science.gov (United States)

    Bazarov, Ivan; Cultrera, Luca; Bartnik, Adam; Dunham, Bruce; Karkare, Siddharth; Li, Yulin; Liu, Xianghong; Maxson, Jared; Roussel, William

    2011-05-01

    Thermal emittance measurements of a CsK2Sb photocathode at several laser wavelengths are presented. The emittance is obtained with a solenoid scan technique using a high voltage dc photoemission gun. The thermal emittance is 0.56±0.03 mm mrad/mm(rms) at 532 nm wavelength. The results are compared with a simple photoemission model and found to be in a good agreement.

  3. Alpha spectrometry for particle size determination of mineral sands dust samples

    International Nuclear Information System (INIS)

    A method is proposed for assessing the size distribution of the radioactive particles directly from the alpha spectrum of a dust sample. The residual range distribution of alpha particles emerging from a sphere containing a monoenergetic alpha emitter is simply a quadratic function of the diameter of the sphere. The residual range distribution from a typical dust particle closely approximates that of a sphere of the same mass. For mixtures of various size particles of similar density the (multiparticle) residual range distribution can thus readily be calculated for each of the alpha emitters contained in the particles. Measurement of the composite residual range distribution can be made in a vacuum alpha spectrometer provided the dust sample has no more than a monolayer of particles. The measured energy distribution is particularly sensitive to upper particle size distributions in the diameter region of 4μm to 20μm of 5 mg/cm3 density particles, i.e. 2 to 10 mg/ch2. For dust particles containing212Po or known ratios of alpha emitters a measured alpha spectrum can be unraveled to the underlying particle size distribution. Uncertainty in the size distribution has been listed as deserving research priority in the overall radiation protection program of the mineral sands industry. The proposed method had the potential of reducing this uncertainty, thus permitting more effective radiation protection control. 2 refs., 1 tabs., 1 figs

  4. Theoretical study of transverse-longitudinal emittance coupling

    Energy Technology Data Exchange (ETDEWEB)

    Qin, H; Davidson, R C; Chung, M; Barnard, J J; Wang, T F

    2011-04-14

    The effect of a weakly coupled periodic lattice in terms of achieving emittance exchange between the transverse and longitudinal directions is investigated using the generalized Courant-Snyder theory for coupled lattices. Recently, the concept and technique of transverse-longitudinal emittance coupling have been proposed for applications in the Linac Coherent Light Source and other free-electron lasers to reduce the transverse emittance of the electron beam. Such techniques can also be applied to the driver beams for the heavy ion fusion and beam-driven high energy density physics, where the transverse emittance budget is typically tighter than the longitudinal emittance. The proposed methods consist of one or several coupling components which completely swap the emittances of one of the transverse directions and the longitudinal direction at the exit of the coupling components. The complete emittance exchange is realized in one pass through the coupling components. In the present study, we investigate the effect of a weakly coupled periodic lattice in terms of achieving emittance exchange between the transverse and longitudinal directions. A weak coupling component is introduced at every focusing lattice, and we would like to determine if such a lattice can realize the function of emittance exchange.

  5. Low emittance electron beam optics commissioning in Indus-2

    International Nuclear Information System (INIS)

    Currently Indus-2 is normally operated with beam emittance of 85 nmrad at 2.0 GeV. In order to reduce the beam emittance to half of this value its dispersion function has been modified by properly choosing the quadrupoles strengths of the lattice. At this low beam emittance optics dynamic aperture reduces and may not be sufficient for beam injection thus a procedure has been evolved and implemented to shift the beam emittance of stored beam at 2.0 GeV. (author)

  6. Fibrous selective emitter structures from sol-gel process

    International Nuclear Information System (INIS)

    Selective emitters have the potential benefit of high efficiency due to the matching of emission spectra to the response of photovoltaic (PV) cells. Continuous uniform rare-earth oxide selective emitter fibers were successfully fabricated using a viscous solution made from metal organic precursors. Cylindrical- and planar configuration emitter structures were made by direct cross-winding or stacking of precursor fiber layers. The combustion and optical performance of the planar emitter structures were tested. The results indicates that both the designing of the fiber packing density and the thickness is critical for high photon and power output

  7. Intelligent Variable Emittance Panels Using New, ""True"" Solid Electrolyte Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This work further developed a highly promising Variable Emittance technology for spacecraft thermal control based on Conducting Polymer (CP) electrochromics...

  8. Capping soft tailings from a floating platform

    Energy Technology Data Exchange (ETDEWEB)

    Costello, M.; Van Kesteren, W.; Hedblom, E. [Alberta Univ., Edmonton, AB (Canada). Oil Sands Tailings Research Facility

    2010-07-01

    This PowerPoint presentation discussed methods of capping oil sands soft tailings from a floating platform. Caps on soft sediments at various locations throughout the world were analyzed in order to determine their water content and surface shear strength. A small-scale raining project was conducted at Stryker Bay to cap tailings with 150,000 m{sup 3} of sand. A small-scale rainbowing project at Soda Lake delivered sand at a rate of between 20 to 60 m{sup 3}/hr. A large-scale rainbowing project in Rotterdam delivered 2000 m{sup 3}/hr of sand. The capping and dredging project cost $12 per m{sup 3}. Case studies of various capping projects were presented in order to describe and demonstrate the floating platform technique as well as the installation of wicks and drains. The method can be used to cap very soft tailings with thin, uniform lifts. tabs., figs.

  9. Direct pulp capping using biodentine

    Directory of Open Access Journals (Sweden)

    Popović-Bajić Marijana

    2014-01-01

    Full Text Available Introduction. Direct pulp capping is therapeutic method of applying medication on exposed pulp in order to allow bridge formation and healing process. The aim of this study was to investigate the effect of Biodentine on exposed dental pulp of Vietnamese pigs. Material and Methods. The study was conducted on 20 teeth of Vietnamese pigs (Sus scrofa domesticus. On buccal surfaces of incisors, canines and first premolars, class V cavities were prepared and pulp was exposed. In the experimental group (six incisors, two canines and two premolars the perforation was covered with Biodentine® (Septodont, Saint-Maur-des-Fosses, France. In the control group, the perforation was covered with MTA® (Dentsply Tulsa Dental, Johnson City, TN, USA. All cavities were restored with glass ionomer cement (GC Fuji VIII, GC Corporation, Tokyo, Japan. Observation period was 28 days. After sacrificing the animals, histological preparations were done to analyze the presence of dentin bridge, an inflammatory reaction of the pulp, pulp tissue reorganization and the presence of bacteria. Results. Dentin bridge was observed in all teeth (experimental and control groups. Inflammation of the pulp was mild to moderate in both groups. Neoangiogenesis and many odontoblast like cells responsible for dentin bridge formation were detected. Necrosis was not observed in any case, neither the presence of Gram-positive bacteria in the pulp. Conclusion. Histological analysis indicated favorable therapeutic effects of Biodentine for direct pulp capping in teeth of Vietnamese pigs. Findings were similar with Biodentine and MTA.

  10. Cap rates and commercial property prices

    OpenAIRE

    Bart Hobijn; John Krainer; David Lang

    2011-01-01

    Commercial real estate capitalization rates have been found to be good indicators of expected returns in commercial properties. Recent declines in these cap rates appear to be signaling a commercial real estate rebound, indicating improved investor expectations of price growth in the market. Movements in national cap rates are the predominant drivers of changes in cap rates in local markets. Therefore, the anticipated commercial real estate rebound is likely to be widespread across many metro...

  11. Ocular injuries from flying bottle caps.

    Science.gov (United States)

    Fonseka, C

    1993-12-01

    Three cases of serious eye injury are described from flying metal caps of carbonated drink bottles. The injuries occurred while attempting to open the bottle in an unconventional and dangerous way. Though injuries from flying bottle caps have been described before, they have occurred when the bottle exploded. This is the first report of eye injuries caused by bottle caps while opening and are similar to the injuries caused by champagne corks. PMID:8143337

  12. Satellite altimeter remote sensing of ice caps

    OpenAIRE

    Rinne, Eero Juhani

    2011-01-01

    This thesis investigates the use of satellite altimetry techniques for measuring surface elevation changes of ice caps. Two satellite altimeters, Radar Altimeter 2 (RA-2) and Geoscience Laser Altimeter System (GLAS) are used to assess the surface elevation changes of three Arctic ice caps. This is the first time the RA-2 has been used to assess the elevation changes of ice caps - targets much smaller than the ice sheets which are the instrument’s primary land ice targets. Algor...

  13. Barium depletion in hollow cathode emitters

    International Nuclear Information System (INIS)

    Dispenser hollow cathodes rely on a consumable supply of Ba released by BaO-CaO-Al2O3 source material in the pores of a tungsten matrix to maintain a low work function surface. The examination of cathode emitters from long duration tests shows deposits of tungsten at the downstream end that appear to block the flow of Ba from the interior. In addition, a numerical model of Ba transport in the cathode plasma indicates that the Ba partial pressure in the insert may exceed the equilibrium vapor pressure of the dominant Ba-producing reaction, and it was postulated previously that this would suppress Ba loss in the upstream part of the emitter. New measurements of the Ba depletion depth from a cathode insert operated for 8200 h reveal that Ba loss is confined to a narrow region near the downstream end, confirming this hypothesis. The Ba transport model was modified to predict the depletion depth with time. A comparison of the calculated and measured depletion depths gives excellent qualitative agreement, and quantitative agreement was obtained assuming an insert temperature 70 °C lower than measured beginning-of-life values

  14. Muon Emittance Exchange with a Potato Slicer

    Energy Technology Data Exchange (ETDEWEB)

    Summers, D. J. [Univ. of Mississippi, Oxford, MS (United States); Hart, T. L. [Univ. of Mississippi, Oxford, MS (United States); Acosta, J. G. [Univ. of Mississippi, Oxford, MS (United States); Cremaldi, L. M. [Univ. of Mississippi, Oxford, MS (United States); Oliveros, S. J. [Univ. of Mississippi, Oxford, MS (United States); Perera, L. P. [Univ. of Mississippi, Oxford, MS (United States); Neuffer, D. V. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2015-04-15

    We propose a novel scheme for final muon ionization cooling with quadrupole doublets followed by emittance exchange in vacuum to achieve the small beam sizes needed by a muon collider. A flat muon beam with a series of quadrupole doublet half cells appears to provide the strong focusing required for final cooling. Each quadrupole doublet has a low beta region occupied by a dense, low Z absorber. After final cooling, normalized transverse, longitudinal, and angular momentum emittances of 0.100, 2.5, and 0.200 mm-rad are exchanged into 0.025, 70, and 0.0 mm-rad. A skew quadrupole triplet transforms a round muon bunch with modest angular momentum into a flat bunch with no angular momentum. Thin electrostatic septa efficiently slice the flat bunch into 17 parts. The 17 bunches are interleaved into a 3.7 meter long train with RF deflector cavities. Snap bunch coalescence combines the muon bunch train longitudinally in a 21 GeV ring in 55 µs, one quarter of a synchrotron oscillation period. A linear long wavelength RF bucket gives each bunch a different energy causing the bunches to drift in the ring until they merge into one bunch and can be captured in a short wavelength RF bucket with a 13% muon decay loss and a packing fraction as high as 87 %.

  15. Muon Emittance Exchange with a Potato Slicer

    CERN Document Server

    Summers, D J; Acosta, J G; Cremaldi, L M; Oliveros, S J; Perera, L P; Neuffer, D V

    2015-01-01

    We propose a novel scheme for final muon ionization cooling with quadrupole doublets followed by emittance exchange in vacuum to achieve the small beam sizes needed by a muon collider. A flat muon beam with a series of quadrupole doublet half cells appears to provide the strong focusing required for final cooling. Each quadrupole doublet has a low beta region occupied by a dense, low Z absorber. After final cooling, normalized transverse, longitudinal, and angular momentum emittances of 0.100, 2.5, and 0.200 mm-rad are exchanged into 0.025, 70, and 0.0 mm-rad. A skew quadrupole triplet transforms a round muon bunch with modest angular momentum into a flat bunch with no angular momentum. Thin electrostatic septa efficiently slice the flat bunch into 17 parts. The 17 bunches are interleaved into a 3.7 meter long train with RF deflector cavities. Snap bunch coalescence combines the muon bunch train longitudinally in a 21 GeV ring in 55 microseconds, one quarter of a synchrotron oscillation period. A linear long ...

  16. Minimizing Emittance for the CLIC Damping Ring

    CERN Document Server

    Braun, H; Levitchev, E; Piminov, P; Schulte, Daniel; Siniatkin, S; Vobly, P P; Zimmermann, Frank; Zolotarev, Konstantin V; CERN. Geneva

    2006-01-01

    The CLIC damping rings aim at unprecedented small normalized equilibrium emittances of 3.3 nm vertical and 550 nm horizontal, for a bunch charge of 2.6·109 particles and an energy of 2.4 GeV. In this parameter regime the dominant emittance growth mechanism is intra-beam scattering. Intense synchrotron radiation damping from wigglers is required to counteract its effect. Here the overall optimization of the wiggler parameters is described, taking into account state-of-the-art wiggler technologies, wiggler effects on dynamic aperture, and problems of wiggler radiation absorption. Two technical solutions, one based on superconducting magnet technology the other on permanent magnets are presented. Although dynamic aperture and tolerances of this ring design remain challenging, benefits are obtained from the strong damping. For optimized wigglers, only bunches for a single machine pulse may need to be stored, making injection/extraction particularly simple and limiting the synchrotron-radiation power. With a 36...

  17. Barium depletion in hollow cathode emitters

    Energy Technology Data Exchange (ETDEWEB)

    Polk, James E., E-mail: james.e.polk@jpl.nasa.gov; Mikellides, Ioannis G.; Katz, Ira [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California 91109 (United States); Capece, Angela M. [Graduate Aerospace Laboratories, California Institute of Technology, Pasadena, California 91125 (United States)

    2016-01-14

    Dispenser hollow cathodes rely on a consumable supply of Ba released by BaO-CaO-Al{sub 2}O{sub 3} source material in the pores of a tungsten matrix to maintain a low work function surface. The examination of cathode emitters from long duration tests shows deposits of tungsten at the downstream end that appear to block the flow of Ba from the interior. In addition, a numerical model of Ba transport in the cathode plasma indicates that the Ba partial pressure in the insert may exceed the equilibrium vapor pressure of the dominant Ba-producing reaction, and it was postulated previously that this would suppress Ba loss in the upstream part of the emitter. New measurements of the Ba depletion depth from a cathode insert operated for 8200 h reveal that Ba loss is confined to a narrow region near the downstream end, confirming this hypothesis. The Ba transport model was modified to predict the depletion depth with time. A comparison of the calculated and measured depletion depths gives excellent qualitative agreement, and quantitative agreement was obtained assuming an insert temperature 70 °C lower than measured beginning-of-life values.

  18. Barium depletion in hollow cathode emitters

    Science.gov (United States)

    Polk, James E.; Mikellides, Ioannis G.; Capece, Angela M.; Katz, Ira

    2016-01-01

    Dispenser hollow cathodes rely on a consumable supply of Ba released by BaO-CaO-Al2O3 source material in the pores of a tungsten matrix to maintain a low work function surface. The examination of cathode emitters from long duration tests shows deposits of tungsten at the downstream end that appear to block the flow of Ba from the interior. In addition, a numerical model of Ba transport in the cathode plasma indicates that the Ba partial pressure in the insert may exceed the equilibrium vapor pressure of the dominant Ba-producing reaction, and it was postulated previously that this would suppress Ba loss in the upstream part of the emitter. New measurements of the Ba depletion depth from a cathode insert operated for 8200 h reveal that Ba loss is confined to a narrow region near the downstream end, confirming this hypothesis. The Ba transport model was modified to predict the depletion depth with time. A comparison of the calculated and measured depletion depths gives excellent qualitative agreement, and quantitative agreement was obtained assuming an insert temperature 70 °C lower than measured beginning-of-life values.

  19. Compact Rare Earth Emitter Hollow Cathode

    Science.gov (United States)

    Watkins, Ronald; Goebel, Dan; Hofer, Richard

    2010-01-01

    A compact, high-current, hollow cathode utilizing a lanthanum hexaboride (LaB6) thermionic electron emitter has been developed for use with high-power Hall thrusters and ion thrusters. LaB6 cathodes are being investigated due to their long life, high current capabilities, and less stringent xenon purity and handling requirements compared to conventional barium oxide (BaO) dispenser cathodes. The new cathode features a much smaller diameter than previously developed versions that permit it to be mounted on axis of a Hall thruster ( internally mounted ), as opposed to the conventional side-mount position external to the outer magnetic circuit ("externally mounted"). The cathode has also been reconfigured to be capable of surviving vibrational loads during launch and is designed to solve the significant heater and materials compatibility problems associated with the use of this emitter material. This has been accomplished in a compact design with the capability of high-emission current (10 to 60 A). The compact, high-current design has a keeper diameter that allows the cathode to be mounted on the centerline of a 6- kW Hall thruster, inside the iron core of the inner electromagnetic coil. Although designed for electric propulsion thrusters in spacecraft station- keeping, orbit transfer, and interplanetary applications, the LaB6 cathodes are applicable to the plasma processing industry in applications such as optical coatings and semiconductor processing where reactive gases are used. Where current electrical propulsion thrusters with BaO emitters have limited life and need extremely clean propellant feed systems at a significant cost, these LaB6 cathodes can run on the crudest-grade xenon propellant available without impact. Moreover, in a laboratory environment, LaB6 cathodes reduce testing costs because they do not require extended conditioning periods under hard vacuum. Alternative rare earth emitters, such as cerium hexaboride (CeB6) can be used in this

  20. Early and continuing effects of combined alpha and beta irradiation of the lung:

    Energy Technology Data Exchange (ETDEWEB)

    Scott, B.R.; Hahn, F.F.; Snipes, M.B.; Newton, G.J.; Eidson, A.F.; Mauderly, J.L.; Boecker, B.B.

    1988-03-01

    This report summarizes an inhalation exposure experiment that concerns early and continuing effects of combined alpha and beta irradiation of the lung of rats. Both morbidity at 18 months and mortality within 18 months after exposure were examined for rats exposed to the beta-emitter /sup 147/Pm, the alpha-emitter /sup 238/Pu, or both combined. The results were used to validate hazard-function models that were developed (1)for pulmonary functional morbidity at 18 months and (2) for lethality from radiation pneumonitis and pulmonary fibrosis within 18 months. Both models were found to adequately predict the experimental observations after combined chronic alpha and beta irradiation of the lung. A relative biological effectiveness of approximately 7 was obtained for /sup 238/Pu alpha radiation compared to /sup 147/Pm beta radiation for both pulmonary functional morbidity and lethality from radiation pneumonitis and pulmonary fibrosis. 12 refs., 16 figs., 11 tabs.

  1. Radiological hazards of waste containing alpha-emitting radionuclides

    International Nuclear Information System (INIS)

    The radiological hazards of alpha-contaminated wastes are discussed in this overview in terms of two components of hazard: radiobiological hazard and radioecological hazard. Radiobiological hazard refers to human uptake of alpha-emitters by inhalation and ingestion, and the resultant dose to critical organs of the body. Radioecological hazard refers to the processes of release from buried wastes, transport in the environment, and translocation to man through the food chain. Besides detailing the sources and magnitude of hazards, this brief review identifies the uncertainties in their estimation, and implications for the regulatory process

  2. Gross alpha radioactivity of drinking water in Venezuela

    International Nuclear Information System (INIS)

    Bottled mineral water is consumed by a large population in Venezuela. The alpha emitters concentration was measured in samples of bottled water and water springs collected near the surface. Approximately 30% of the total mineral water suppliers was monitored. a database on natural and artificial radioactivity in drinking water was produced. Results indicate that 54% of the waters sampled contain a total alpha radioactivity of less than 0.185 Bql-1 and only 12% above 0.37 Bql-1. Our results revealed a total annual dose of 2.3 mSv year-1. (author)

  3. Effective liquid drop description for alpha decay of atomic nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Tavares, O.A.P.; Duarte, S.B. [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Rodriguez, O.; Guzman, F. [Instituto Superior de Ciencia y Tecnologia Nuclear (ISCTN), La Habana (Cuba); Goncalves, M. [Instituto de Radioprotecao e Dosimetria (IRD), Rio de Janeiro, RJ (Brazil); Garcia, F. [Sao Paulo Univ., SP (Brazil). Inst. de Fisica

    1998-06-01

    Alpha decay half-lives are presented in the framework of an effective liquid drop model for different combination of mass transfer descriptions and inertia coefficients. Calculated half-life-values for ground-state to ground-state favoured alpha transitions are compared with available, updated experimental data. Results have shown that the present model is very suitable to treat the alpha decay process on equal foot as cluster radioactivity and cold fission processes. Better agreement with the data is found when the sub-set of even-even alpha emitters are considered in the calculation. (author) 44 refs., 5 figs., 3 tabs.; e-mail: telo at ird.gov.br

  4. Synthesis, Characterization, and Tribological Behavior of Oleic Acid Capped Graphene Oxide

    Directory of Open Access Journals (Sweden)

    Tiedan Chen

    2014-01-01

    Full Text Available Graphene oxide (GO nanosheets were prepared by modified Hummers and Offeman methods. Furthermore, oleic acid (OA capped graphene oxide (OACGO nanosheets were prepared and characterized by means of Fourier transform-infrared spectroscopy (FT-IR, transmission electron microscopy (TEM, and X-ray diffraction (XRD. At the same time, the friction and wear properties of OA capped graphite powder (OACG, OACGO, and oleic acid capped precipitate of graphite (OACPG as additives in poly-alpha-olefin (PAO were compared using four-ball tester and SRV-1 reciprocating ball-on-disc friction and wear tester. By the addition of OACGO to PAO, the antiwear ability was improved and the friction coefficient was decreased. Also, the tribological mechanism of the GO was investigated.

  5. The cervical cap: a barrier contraceptive.

    Science.gov (United States)

    Hastings-Tolsma, M T

    1982-01-01

    The cervical cap may eventually prove to be a safe, satisfactory, noninvasive, and nonhormonal contraceptive alternative for women in the US. The cap is currently approved for investigational use only, and is available from a limited number of providers. The Prentif cavity rim cap is the most commonly used and is available in 4 sizes. The soft rubber device is thimble shaped, approximately 1 1/4 inches long, with a narrow groove along the inner surface that creates a suction seal when fitted over the cervix. The inability to match cap and cervical circumferences precisely is a recognized drawback. Theoretically, the cap alone should prevent sperm entry into the uterus, however, the use of a spermicide placed in the dome before insertion is recommended. The cap's effectiveness is not yet documented. Estimates from a 1953 study of 143 users were 92.4/100 women years of use for use effectiveness, and the theoretical effectiveness is believed to be more than 98%. Failures with the cap may result from a variety of reasons, particularly dislodgement. The advantage of the cap over other barrier methods is that it can be inserted any time prior to intercourse and left in place longer. The ideal safety period for placement has not been validated, but a range of 1-7 days has been recommended. The length of time the spermicide remains effective and the cervical effects of prolonged contact are of prime concern. The cap may be used by some women who cannot be properly fitted for a diaphragm due to vaginal or uterine anomalies. Sexual arousal and orgasmic response are reported by some cap users to be more pleasurable with the cap than with the diaphragm. Reported problems with use include discomfort during intercourse and improper fit during some days of the menstrual cycle. Contraindications for use include cervical inconsistencies, infection, allergy to the spermicide or the rubber, and inability to learn proper insertion and removal techniques. Insertion and removal may be

  6. Vertically integrated (Ga, In)N nanostructures for future single photon emitters operating in the telecommunication wavelength range

    International Nuclear Information System (INIS)

    Important technological steps are discussed and realized for future room-temperature operation of III-nitride single photon emitters. First, the growth technology of positioned single pyramidal InN nanostructures capped by Mg-doped GaN is presented. The optimization of their optical characteristics towards narrowband emission in the telecommunication wavelength range is demonstrated. In addition, a device concept and technology was developed so that the nanostructures became singularly addressable. It was found that the nanopyramids emit in the telecommunication wavelength range if their size is chosen appropriately. A p-GaN contacting layer was successfully produced as a cap to the InN pyramids and the top p-contact was achievable using an intrinsically conductive polymer PEDOT:PSS, allowing a 25% increase in light transmittance compared to standard Ni/Au contact technology. Single nanopyramids were successfully integrated into a high-frequency device layout. These decisive technology steps provide a promising route to electrically driven and room-temperature operating InN based single photon emitters in the telecommunication wavelength range. (paper)

  7. Determination of Pu and total alpha activity in spent TBP/kerosene

    International Nuclear Information System (INIS)

    Determination of the activity of total Pu and total a in the spent TBP/kerosene is essential to the research on spent TBP/kerosene treatment and disposal of industrialization. Accordingly, a reliable procedure for determining of the activities of total Pu and alpha in spent TBP/kerosene was developed. It is well known that the large area grid ionization chamber alpha spectrometry is a suitable technique to determine the trace-level alpha emitters such as 238U, 237Np, 239+240Pu, 238Pu and 241Am present in samples. However, the spent TBP/kerosene sample cannot be prepared for the source because of the diffusion when it is heated. So the digestion of the spent TBP/ kerosene is needed in this work. Before the digestion, the kerosene in the sample was distilled out for pre-concentration because of the low-level alpha-emitters, which also conduce to the digestion of the sample. After the distillation, the residual TBP was digested with HNO3 and HClO4. For the determination of the total Pu, ion-exchange chromatography was used for chemical separation of Pu, and then the large area grid ionization chamber alpha spectrometry was used for the measurement. The RSD of the Pu measurement was less than 2%. Two recovery experiments were undergone for the test of effect of the ion-exchange separation, and the results of recovery rate was 97.9% and 102%. The spent TBP/kerosene sample was digested with HNO3. After the digestion, the source was prepared for the total alpha-activity measurement. The result of this measurement was not satisfied because the sample cannot be digested entirely with HNO3, some alpha particles were shielded for detection because of self-absorption. However the alpha particle spectrum taken indicated that the percentages of the activities of alpha-emitters were similar in every measurement because of the similar shielding. So the total activities of alpha-emitters were corrected by a factor, which was the ratio of the accurate 239+240Pu activity measured

  8. The North Zealand CAP Monitor

    DEFF Research Database (Denmark)

    Nielsen, Minna; Ravn, Pernille; Notander Clausen, Lise;

    2016-01-01

    patients with CAP and effects of interventions to improve the quality of their care. Based on current literature we defined and tested a set of indicators and designed an audit form, a database and a dashboard for presenting the results. Two nurses monthly audited randomly selected files of patients with...... team of clinicians from the emergency department and inpatient units. Measurement of improvement Audit results are presented as a multidimensional dashboard of aggregated baseline data and run charts to monitor changes. Microbiological tests were delayed, often performed after antibiotics were started...... considered necessary required too tedious data collection or were not useful. So, we could reduce the number of indicators by nearly a third. Important steps from audit to quality dashboard were: Defining and testing audit variables Testing the audit form Defining indicators based on the audit variables...

  9. The determination of gross alpha activity in water by co-precipitation

    International Nuclear Information System (INIS)

    Co-precipitation method is suitable mean for determination of gross alpha activity in water with high salt compounds. Alpha emitters which are Actinides and those in Uranium-Radium series are co-precipitated with barium carrier and iron carrier. Although the activity is not indicative of any specific nuclides presented but it can be used as an index to the radioactive contamination of the waters

  10. Jamming of Quantum Emitters by Active Coated Nanoparticles

    DEFF Research Database (Denmark)

    Arslanagic, Samel; Ziolkowski, Richard W.

    2013-01-01

    effectively cloak the emitters to a far-field observer is reported and explained through thorough near- and far-field investigations. This property offers an interesting route toward the jamming of quantum emitters/nanoantennas that might be of potential use, for instance, in biological fluorescence assays...

  11. Emittance formula for slits and pepper-pot measurement

    International Nuclear Information System (INIS)

    In this note, a rigid formula for slits and pepper-pot emittance measurement is derived. The derivation is based on the one- dimensional slit measurement setup. A mathematical generalization of the slit emittance formula to the pepper-pot measurement is discussed

  12. Thermionic scanner pinpoints work function of emitter surfaces

    Science.gov (United States)

    Rasor, N. S.

    1966-01-01

    In the electron tube testing, a thermionic scanner makes accurate spatial resolution measurements of the metallic surface work functions of emitters. The scanner determines the emitter function and its local departures from the mean value on a point-by-point basis for display on an oscilloscope.

  13. Emittance measurements of low-energy beam line at KVI

    NARCIS (Netherlands)

    Toprek, D; Formanoy, [No Value

    2006-01-01

    In this paper is represented the results of beam profile measurements of He-3(+) beam delivered from ECR ion source at KVI. The beam emittance is estimated by varying quadrupole method. The estimated values for the beam emittance at the different profile grid locations along the transport beam line

  14. Emittance growth due to dipole ripple and sextupole

    International Nuclear Information System (INIS)

    Ripple in the power supplies for storage ring magnets can have adverse effects on the circulating beams: orbit distortion and emittance growth from dipole ripple, tune modulation and dynamic aperture reduction from quadrupole ripple, etc. In this paper, we study the effects of ripple in the horizontal bending field of the SSC in the presence of nonlinearity, in particular, the growth in beam emittance

  15. Emittance growth due to dipole ripple and sextupole

    Energy Technology Data Exchange (ETDEWEB)

    Shih, H.J.; Ellison, J.A.; Syphers, M.J.; Newberger, B.S.

    1993-05-01

    Ripple in the power supplies for storage ring magnets can have adverse effects on the circulating beams: orbit distortion and emittance growth from dipole ripple, tune modulation and dynamic aperture reduction from quadrupole ripple, etc. In this paper, we study the effects of ripple in the horizontal bending field of the SSC in the presence of nonlinearity, in particular, the growth in beam emittance.

  16. Coated nano-particle jamming of quantum emitters

    DEFF Research Database (Denmark)

    Arslanagic, Samel; Ziolkowski, Richard W.

    2012-01-01

    Spherical active coated nano-particles are examined analytically and numerically in the presence of one, two or four quantum emitters (electric Hertzian dipoles). The ability of the coated nano-particle to effectively cloak the emitters to a far-field observer is reported. This offers an...

  17. Sharpening of field emitter tips using high-energy ions

    Science.gov (United States)

    Musket, Ronald G.

    1999-11-30

    A process for sharpening arrays of field emitter tips of field emission cathodes, such as found in field-emission, flat-panel video displays. The process uses sputtering by high-energy (more than 30 keV) ions incident along or near the longitudinal axis of the field emitter to sharpen the emitter with a taper from the tip or top of the emitter down to the shank of the emitter. The process is particularly applicable to sharpening tips of emitters having cylindrical or similar (e.g., pyramidal) symmetry. The process will sharpen tips down to radii of less than 12 nm with an included angle of about 20 degrees. Because the ions are incident along or near the longitudinal axis of each emitter, the tips of gated arrays can be sharpened by high-energy ion beams rastered over the arrays using standard ion implantation equipment. While the process is particularly applicable for sharpening of arrays of field emitters in field-emission flat-panel displays, it can be effectively utilized in the fabrication of other vacuum microelectronic devices that rely on field emission of electrons.

  18. Spectral beam combining of multi-single emitters

    Science.gov (United States)

    Wang, Baohua; Guo, Weirong; Guo, Zhijie; Xu, Dan; Zhu, Jing; Zhang, Qiang; Yang, Thomas; Chen, Xiaohua

    2016-03-01

    Spectral beam combination expands the output power while keeps the beam quality of the combined beam almost the same as that of a single emitter. Spectral beam combination has been successfully achieved for high power fiber lasers, diode laser arrays and diode laser stacks. We have recently achieved the spectral beam combination of multiple single emitter diode lasers. Spatial beam combination and beam transformation are employed before beams from 25 single emitter diode lasers can be spectrally combined. An average output power about 220W, a spectral bandwidth less than 9 nm (95% energy), a beam quality similar to that of a single emitter and electro-optical conversion efficiency over 46% are achieved. In this paper, Rigorous Coupled Wave analysis is used to numerically evaluate the influence of emitter width, emitter pitch and focal length of transform lens on diffraction efficiency of the grating and spectral bandwidth. To assess the chance of catastrophic optical mirror damage (COMD), the optical power in the internal cavity of a free running emitter and the optical power in the grating external cavity of a wavelength locked emitter are theoretically analyzed. Advantages and disadvantages of spectral beam combination are concluded.

  19. ALEPH separated barrel and end-caps

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    The end-caps can be seen at the left and right of the image with the barrel at the centre. Technicians inspect the end-cap before they begin to take it apart. ALEPH was an experiment on the LEP accelerator, which studied high-energy collisions between electrons and positrons from 1989 to 2000.

  20. Emittance compensation of CW DC-gun photoinjector

    International Nuclear Information System (INIS)

    Emittance growth induced by space charge effect is very important, especially for CW DC-gun photoinjector. In this work, the linear space charge force and its effect on electron beam transverse emittance are studied, and the principle and properties of emittance compensation by solenoid are analyzed. The CAEP DC-gun photoinjector with a solenoid is also simulated by code Parmela. Simulated results indicate that the normalized transverse emittance of an 80 pC bunch at the 350 keV DC-gun ex-it is 5.14 mm · mrad. And after compensated by a solenoid, it becomes 1.27 mm · mrad. The emittance of beam is well compensated. (authors)

  1. Emittance Measurements for Beams Extracted from LECR3 Ion Source

    Institute of Scientific and Technical Information of China (English)

    CaoYun; ZhaoHongwei; MaLei; ZhangZimin

    2003-01-01

    High quality ion beams are required by IMP cyclotron and atomic physics research, so it is important to research and measure beam emitt ance of ECR ion source. Intense beams extracted from ECR ion source usually have low energy, so it is suitable to use Electric-Sweep Scanner to measure the emittance. This kind of measurement is popularly used at ECR ion source, and it has some prominent merits such as high accuracy, very short time of data processing and easy expressing of the emittance pattern. So we designed and built this emittance scanner to measure emittance of the ion beams produced by LECR3 ion source. The structure of the ESS is shown in Fig.l, and the photo of the ESS is shown in Fig.2.

  2. Vacuum Rabi spectra of a single quantum emitter

    CERN Document Server

    Ota, Yasutomo; Kumagai, Naoto; Iwamoto, Satoshi; Arakawa, Yasuhiko

    2015-01-01

    We report the observation of the vacuum Rabi splitting of a single quantum emitter by measuring its direct spontaneous emission into free space. We used a semiconductor quantum dot inside a photonic crystal nanocavity, in conjunction with an appropriate cavity design and filtering with a polarizer and an aperture, enabling the extraction of the inherently-weak emitter's signal. The emitter's vacuum Rabi spectra exhibit clear differences to those measured by detecting the cavity photon leakage. Moreover, we observed an asymmetric vacuum Rabi spectrum induced by interference between the emitter and cavity detection channels. Our observations lay the groundwork for accessing various cavity quantum electrodynamics phenomena that manifest themselves only in the emitter's direct spontaneous emission.

  3. Properties of nanolasers based on few discrete emitters

    DEFF Research Database (Denmark)

    Lund, Anders Mølbjerg; Nielsen, Per Kær; Lorke, Michael;

    2012-01-01

    The laser has evolved from table size apparatuses to truly nano sized devices, in much the same way that computer chips have been continuously minimized. The few-emitter nanolaser represents an extreme in terms of size. The emitters can be either atoms or quantum dots, and they are coupled to a......-level systems are pumped incoherently by a rate P. Solutions are found using the corresponding master equation. However, with cavity populations exceeding 100 and several emitters, the dimension of the Hilbert space of the system becomes too large to handle efficiently on a conventional computer. E.g. for four...... population of the cavity, na, and the occupation of the emitters. Fig. 1a) shows na for up to 4 emitters coupled to a cavity, as a function of the pumping rate P. The figure also shows results from a full master equation solution, and the correspondence is very good for large values of P. In Fig. 1b) the...

  4. Space Charge Effects in Rectilinear Motion Emittance

    CERN Document Server

    Chen, C

    2000-01-01

    This report summarizes the presentations and discussions over a wide range of topics in Working Group I at the Second ICFA Advanced Accelerator Workshop on Physics of High-Brightness Beams held at University of California at Los $9 Angeles (UCLA), November 9-12, 1999. Latest developments towards to a better understanding of high-brightness photoinjectors were reported. The design and commissioning of the Los Alamos National Laboratory (LANL) Low-Energy $9 Demonstration Accelerator (LEDA) Radio-Frequency Quadrupole (RFQ) were reported. The problem of beam halo formation was discussed in both beam transport systems and the SLAC 50 MW 11.4 GHz periodic permanent magnet (PPM) focusing $9 klystron amplifier. A new class of corkscrewing elliptic beam equilibria was reported, and applications of such novel beam equilibria in controlling of charge-density and velocity fluctuations, beam halo formation and emittance $9 growth were discussed. Pattern formation in proton rings was also discussed.

  5. Gamma emitters in Hong Kong water

    International Nuclear Information System (INIS)

    Radioactivity in water originates from natural and artificial sources. The development of a nuclear powerplant near Hong Kong necessitates that attention be given to formulating techniques to assess the possible resultant environmental radioactive contamination. Water samples collected from various sites in Hong Kong in the spring and summer of 1987, representing seawater, river water, reservoir water, drinking water, and underground water were studied through gamma-ray spectral analysis. Only gamma emitters in the U238 and Th232 series and K40 were detected. No fission product was detected with specific activity above 0.1 Bq/kg. The data could be the baseline for future monitoring of the radioactivity released from a nuclear plant being built at a 50-km distance from Hong Kong. The variation of detected specific activities may be due to geological differences and the effect of plants. 1 ref., 3 tabs

  6. Mesoscopic quantum emitters coupled to plasmonic nanostructures

    DEFF Research Database (Denmark)

    Andersen, Mads Lykke

    -photon sources using self-assembled quantum dots. The measured decay dynamics of quantum dots in proximity to semiconductor/ metal interfaces reveal that the dipole approximation generally does not hold for quantum dots due to their mesoscopic size. In order to explain the observations, a theoretical model for...... the spontaneous emission of mesoscopic quantum emitters is developed. The light-matter interaction is in this model modied beyond the dipole expectancy and found to both suppress and enhance the coupling to plasmonic modes in excellent agreement with our measurements. We demonstrate that this...... mesoscopic effect can be utilized to strongly modify the coupling to plasmonic modes on metal nanowires and gap waveguides and we propose its use for spontaneous-emission control beyond the dipole approximation in nano-structured environments in general. The mesoscopic effect can be utilized to strongly...

  7. Preparation of an emittance transfer experiment

    CERN Document Server

    Xiao, C; Groening, L; Leibrock, H; Maier, M

    2012-01-01

    Flat beams feature unequal emittances in the horizontal and vertical phase space. Those beams were created successfully in lepton machines. Although a number of applications will profit also from flat hadron beams, to our knowledge they have never been created systematically. Multi-turn injection schemes, spectrometers, and colliders will directly benefit from those beams. The present paper covers the preparation of the experimental proof of principle for flat hadron beam creation in a beam transport section. Detailed simulations of the experiment, based on charge state stripping inside of a solenoid [L. Groening, Phys. Rev. ST Accel. Beams 14, 064201 (2011)], are performed. The matrix formalism was benchmarked with tracking through three-dimensional magnetic field maps of solenoids. An error analysis targeting at investigation of the impact of machine errors on the round-to-flat beam transformation has been performed. The remarkable flexibility of the set-up w.r.t. decoupling is addressed, as it can provide ...

  8. Emittance compensation for an SRF photo injector

    Energy Technology Data Exchange (ETDEWEB)

    Vennekate, H.; Lu, P. [HZDR (Germany); TU Dresden (Germany); Arnold, A.; Mucek, P.; Teichert, J.; Xiang, R. [HZDR (Germany); Kamps, T. [HZB (Germany); Kneisel, P. [JLab (Germany); Voelker, J. [HZB (Germany); Humboldt Universitaet Berlin (Germany); Volkov, V. [BINP (Germany); Will, I. [MBI (Germany)

    2013-07-01

    The development of a superconducting photo injector is an ongoing challenge at the HZDR in Dresden. Several milestones like the first operation of a half cell niobium cavity in 2002 and the worldwide first beam transfer from a 3 1/2-cell SRF gun into an actual accelerator structure have already been accomplished. Nevertheless, as superconducting electron sources are of great interest for future ERL or cw operated FEL projects, studies to improve their output parameters and stability continue to get them on the same level as their normal conducting counterparts. The talk discusses several of the current approaches to reduce the transversal emittance of the next 3 1/2-cell cavity at the HZDR including the installation of a superconducting solenoid within the gun's cryostat.

  9. Liquid scintillation counting techniques for the determination of some alpha emitting actinides: a review

    International Nuclear Information System (INIS)

    The present report is a review of the work on liquid scintillation counting techniques, for the determination of alpha emitting actinides like uranium, plutonium, americium etc; for the last three decades (1970-1999). It covers the progress that has taken place in conventional liquid scintillation counting employing various solvents, scintillators and extractants. There is gradual development in instrumentation from integral counting of alpha emitters to alpha liquid scintillation spectrometry to resolve and identify different alpha emitters. These advancements have led to Pulse Shape Analysis (PSA) and Photon Electron Rejecting Alpha Liquid Scintillation Spectrometry (PERALS) techniques for the determination of the alpha emitters in the presence of beta and gamma activity. These techniques allow the determination of actinides at very low levels which has increased their applications to almost all the fields of chemistry; be it biomedical, environmental, geological or process chemistry of nuclear fuels. The development of biphasic technique using various extractants to separate different elements and counting in presence of one another has been made possible. Inorganic scintillators have been recently developed which have the advantage of eliminating effects of quenching and presence of beta/gamma emitting actinides. This review will serve as a reference to those who want to carry out work in the field of determination of actinides using liquid scintillation counting techniques. (author)

  10. Microtubule dynamics: Caps, catastrophes, and coupled hydrolysis

    DEFF Research Database (Denmark)

    Flyvbjerg, H.; Holy, T.E.; Leibler, S.

    1996-01-01

    An effective theory is formulated for the dynamics of the guanosine triphosphate (GTP) cap believed to stabilize growing microtubules. The theory provides a ''coarse-grained'' description of the cap's dynamics. ''Microscopic'' details, such as the microtubule lattice structure and the fate of its...... data. A constant nonzero catastrophe rare, identical for both microtubule ends, is predicted at large growth rates. The delay time for dilution-induced catastrophes is stochastic with a simple distribution that fits the experimental one and, like the experimental one, does not depend on the rate of....... A recent experimental result for the size of the minimal cap that can stabilize a microtubule is shown to agree with the result predicted by the cap model, after its parameters have been extracted from previous experimental results. Thus the effective theory and cap model presented here provide a...

  11. Physical electrostatics of small field emitter arrays/clusters

    Science.gov (United States)

    Forbes, Richard G.

    2016-08-01

    This paper aims to improve qualitative understanding of electrostatic influences on apex field enhancement factors (AFEFs) for small field emitter arrays/clusters. Using the "floating sphere at emitter-plate potential" (FSEPP) model, it re-examines the electrostatics and mathematics of three simple systems of identical post-like emitters. For the isolated emitter, various approaches are noted. An adequate approximation is to consider only the effects of sphere charges and (for significantly separated emitters) image charges. For the 2-emitter system, formulas are found for charge-transfer ("charge-blunting") effects and neighbor-field effects, for widely spaced and for "sufficiently closely spaced" emitters. Mutual charge-blunting is always the dominant effect, with a related (negative) fractional AFEF-change δtwo. For sufficiently small emitter spacing c, |δtwo| varies approximately as 1/c; for large spacing, |δtwo| decreases as 1/c3. In a 3-emitter equispaced linear array, differential charge-blunting and differential neighbor-field effects occur, but differential charge-blunting effects are dominant, and cause the "exposed" outer emitters to have higher AFEF (γ0) than the central emitter (γ1). Formulas are found for the exposure ratio Ξ = γ0/γ1, for large and for sufficiently small separations. The FSEPP model for an isolated emitter has accuracy around 30%. Line-charge models (LCMs) are an alternative, but an apparent difficulty with recent LCM implementations is identified. Better descriptions of array electrostatics may involve developing good fitting equations for AFEFs derived from accurate numerical solution of Laplace's equation, perhaps with equation form(s) guided qualitatively by FSEPP-model results. In existing fitting formulas, the AFEF-reduction decreases exponentially as c increases, which is different from the FSEPP-model formulas. This discrepancy needs to be investigated, using systematic Laplace-based simulations and appropriate results

  12. Effect of thin emitter set-back layer on GaAs delta-doped emitter bipolar junction transistor

    Science.gov (United States)

    Lew, K. L.; Yoon, S. F.

    2005-05-01

    GaAs delta-doped emitter bipolar junction transistors (δ-BJT) with different emitter set-back layer thicknesses of 10to50nm were fabricated to study the emitter set-back layer thickness effect on device dc performance. We found that the current gain decreases following decrease in the emitter set-back layer thickness. A detailed analysis was performed to explain this phenomenon, which is believed to be caused by reduction of the effective barrier height in the δ-BJT. This is due to change in the electric-field distribution in the delta-doped structure caused by the built-in potential of the base-emitter (B-E ) junction. Considering the recombination and barrier height reduction effects, the thickness of the emitter set-back layer should be designed according to the B-E junction depletion width with a tolerance of ±5nm. The dc performance of a δ-BJT designed based on this criteria is compared to that of a Al0.25Ga0.75As /GaAs heterojunction bipolar transistor (HBT). Both devices employed base doping of 2×1019cm-3 and base-to-emitter doping ratio of 40. Large emitter area (AE≈1.6×10-5cm-2) and small emitter area (AE≈1.35×10-6cm-2) device current gains of 40 and 20, respectively, were obtained in both types of transistors passivated by (NH4)2S treatment. The measured current gain of the GaAs δ-BJT is the highest reported for a homojunction device with such high base-to-emitter doping ratio normally used in HBT devices.

  13. Alpha activity measurements in Anarak copper mine

    International Nuclear Information System (INIS)

    Alpha radiations in the ground arises from the decay of naturally occurring uranium and thorium, which are widely distributed in soils and rocks. According to Environmental Protection Agency (EPA) reports, the highest of alpha activity is found in locations near copper mines. In this study, the amounts of natural activity of alpha emitters for 31 samples of surface soil of Talmesi Anarak mine, located in center of Iran, are measured by Nuclear Track method. Having virtually zero background and exposure time, are advantages of this method. After sampling, all of the 31 samples were transferred to laboratory to place CR-39 detectors vertically in them. In next step, CR-39 detectors were etched in NaOH 6 M, aqueous solution at 70 °C for 4 h. Then, number of tracks per area unit was counted by an optical microscope. The amounts of alpha activity were calculated in all samples and range of minimum 1.40E + 04 to maximum 3.03E + 05 Bq/kg .And also the activity of Th-232 and U-238 are measured by alpha-track method. Moreover “equivalent uranium” (eU) and “equivalent thorium” (eTh) by Hp-Ge detector, were calculated. - Highlights: ► We studied measuring the alpha activity in soils samples near copper mine by CR-39. ► According to experiments and mechanism of track formation, 2 formulas have introduced. ► We studied the accuracy of 2 formulas and present the optimal formula. ► Our results show these formulas are the same. ► Also we could calculate the concentration of U-238 and Th-232 by results of CR-39

  14. Genetic ablation of root cap cells in Arabidopsis

    OpenAIRE

    Tsugeki, Ryuji; Fedoroff, Nina V.

    1999-01-01

    The root cap is increasingly appreciated as a complex and dynamic plant organ. Root caps sense and transmit environmental signals, synthesize and secrete small molecules and macromolecules, and in some species shed metabolically active cells. However, it is not known whether root caps are essential for normal shoot and root development. We report the identification of a root cap-specific promoter and describe its use to genetically ablate root caps by directing root cap-specific expression of...

  15. Low-emittance tuning at the Cornell Electron Storage Ring

    CERN Document Server

    Shanks, James; Sagan, David

    2013-01-01

    In 2008 the Cornell Electron/Positron Storage Ring (CESR) was reconfigured from an electron/positron collider to serve as a testbed for the International Linear Collider (ILC) damping rings. One of the primary goals of the CESR Test Accelerator (CesrTA) project is to develop low emittance tuning techniques to achieve sub-10pm geometric vertical emittance at 2.085 GeV. This paper discusses the tuning methods used at CesrTA to achieve low-emittance conditions. A minimum vertical emittance of 8.7 +2.9/-3.4(sys) +/-0.2(stat) pm has been achieved at 2.085 GeV. In various configurations and beam energies the correction technique routinely achieves vertical emittance <15 pm after correction. Beam-based measurement and correction requires about 15 minutes. Simulations modeling the effects of magnet misalignments, BPM errors, and emittance correction algorithm suggest the residual vertical emittance measured at the conclusion of the tuning procedure is dominated by sources other than optics errors and misalignments...

  16. The pharmaceutical vial capping process: Container closure systems, capping equipment, regulatory framework, and seal quality tests.

    Science.gov (United States)

    Mathaes, Roman; Mahler, Hanns-Christian; Buettiker, Jean-Pierre; Roehl, Holger; Lam, Philippe; Brown, Helen; Luemkemann, Joerg; Adler, Michael; Huwyler, Joerg; Streubel, Alexander; Mohl, Silke

    2016-02-01

    Parenteral drug products are protected by appropriate primary packaging to protect against environmental factors, including potential microbial contamination during shelf life duration. The most commonly used CCS configuration for parenteral drug products is the glass vial, sealed with a rubber stopper and an aluminum crimp cap. In combination with an adequately designed and controlled aseptic fill/finish processes, a well-designed and characterized capping process is indispensable to ensure product quality and integrity and to minimize rejections during the manufacturing process. In this review, the health authority requirements and expectations related to container closure system quality and container closure integrity are summarized. The pharmaceutical vial, the rubber stopper, and the crimp cap are described. Different capping techniques are critically compared: The most common capping equipment with a rotating capping plate produces the lowest amount of particle. The strength and challenges of methods to control the capping process are discussed. The residual seal force method can characterize the capping process independent of the used capping equipment or CCS. We analyze the root causes of several cosmetic defects associated with the vial capping process. PMID:26654992

  17. Capping stack: An industry in the making

    Institute of Scientific and Technical Information of China (English)

    Jack Chen; Li Xunke; Xie Wenhui; Kang Yongtian

    2013-01-01

    This paper gives an overview of recent development of the marine well containment system (MWCS)after BP Macondo subsea well blowout occurred on April 20,2010 in the Gulf of Mexico.Capping stack,a hardware utilized to contain blowout well at or near the wellhead is the center piece of MWCS.Accessibility to the dedicated capping stacks is gradually becoming a pre-requirement to obtain the permit for offshore drilling/workover,and the industry for manufacturing,maintenance,transportation and operation of the capping stack is in the making.

  18. Improved Rare-Earth Emitter Hollow Cathode

    Science.gov (United States)

    Goebel, Dan M.

    2011-01-01

    An improvement has been made to the design of the hollow cathode geometry that was created for the rare-earth electron emitter described in Compact Rare Earth Emitter Hollow Cathode (NPO-44923), NASA Tech Briefs, Vol. 34, No. 3 (March 2010), p. 52. The original interior assembly was made entirely of graphite in order to be compatible with the LaB6 material, which cannot be touched by metals during operation due to boron diffusion causing embrittlement issues in high-temperature refractory materials. Also, the graphite tube was difficult to machine and was subject to vibration-induced fracturing. This innovation replaces the graphite tube with one made out of refractory metal that is relatively easy to manufacture. The cathode support tube is made of molybdenum or molybdenum-rhenium. This material is easily gun-bored to near the tolerances required, and finish machined with steps at each end that capture the orifice plate and the mounting flange. This provides the manufacturability and robustness needed for flight applications, and eliminates the need for expensive e-beam welding used in prior cathodes. The LaB6 insert is protected from direct contact with the refractory metal tube by thin, graphite sleeves in a cup-arrangement around the ends of the insert. The sleeves, insert, and orifice plate are held in place by a ceramic spacer and tungsten spring inserted inside the tube. To heat the cathode, an insulating tube is slipped around the refractory metal hollow tube, which can be made of high-temperature materials like boron nitride or aluminum nitride. A screw-shaped slot, or series of slots, is machined in the outside of the ceramic tube to constrain a refractory metal wire wound inside the slot that is used as the heater. The screw slot can hold a single heater wire that is then connected to the front of the cathode tube by tack-welding to complete the electrical circuit, or it can be a double slot that takes a bifilar wound heater with both leads coming out

  19. Method and apparatus for multispray emitter for mass spectrometry

    Science.gov (United States)

    Smith, Richard D.; Tang, Keqi; Lin, Yuehe

    2004-12-14

    A method and apparatus that utilizes two or more emitters simultaneously to form an electrospray of a sample that is then directed into a mass spectrometer, thereby increasing the total ion current introduced into an electrospray ionization mass spectrometer, given a liquid flow rate of a sample. The method and apparatus are most conveniently constructed as an array of spray emitters fabricated on a single chip, however, the present invention encompasses any apparatus wherein two or more emitters are simultaneously utilized to form an electrospray of a sample that is then directed into a mass spectrometer.

  20. Direct Observation of Ultralow Vertical Emittance using a Vertical Undulator

    Energy Technology Data Exchange (ETDEWEB)

    Wootton, Kent

    2015-09-17

    In recent work, the first quantitative measurements of electron beam vertical emittance using a vertical undulator were presented, with particular emphasis given to ultralow vertical emittances [K. P. Wootton, et al., Phys. Rev. ST Accel. Beams, 17, 112802 (2014)]. Using this apparatus, a geometric vertical emittance of 0.9 ± 0.3 pm rad has been observed. A critical analysis is given of measurement approaches that were attempted, with particular emphasis on systematic and statistical uncertainties. The method used is explained, compared to other techniques and the applicability of these results to other scenarios discussed.

  1. A General Slice Moment Decomposition of RMS Beam Emittance

    CERN Document Server

    Mitchell, Chad

    2015-01-01

    The square of the horizontal projected (rms) beam emittance is expressed as the sum of four nonnegative contributions, each described using the slice moments of the beam and possessing a natural interpretation in terms of the geometrical properties of the beam in the six-dimensional phase space. The mathematical formalism describing the relationships between projected beam quantities and slice beam quantities is reviewed. The results may be used to reconstruct the moments and emittances of the beam from the moments of its subpopulations, as well as to isolate and better understand a variety of slice and interslice dynamical contributions to the projected beam emittance growth.

  2. Scaled, circular-emitter Penning SPS for intense H- beams

    International Nuclear Information System (INIS)

    The Los Alamos versions of the Penning Surface-Plasma Source (SPS) routinely generate H- ion beams with pulsed currents over 100 mA. However, these sources employ geometries that result in the extraction of slit beams (0.5 x 10 mm2). Our modeling with the SNOW code indicates that the beam from a 5.4-mm-diam circular emitter will have lower emittance and divergence for transport to and injection into our radio-frequency quadrupole (RFQ) accelerator. This paper describes a newly constructed Penning SPS that has most of its discharge chamber dimensions scaled up by a factor of 4 to accommodate this circular emitter

  3. Emittance Measurement with Upgraded RF Gun System at SPring-8

    CERN Document Server

    Mizuno, Akihiko; Hanaki, Hirofumi; Taniuchi, Tsutomu; Tomizawa, Hiromitsu; Uesaka, Mitsuru

    2005-01-01

    A single cell S-band RFgun has been developed at the SPring-8 since 1996. The minimum normalized beam emittance, measured with double slits' scanning method in 2002, was 2.3 pi mm mrad at the exit of the gun cavity with charge of 0.1 nC/bunch. In 2004, we installed a following accelerator structure to investigate beam behavior of the whole injector system. In this paper, we report emittance measurement results of upgraded system, using variable quadrupole magnet method. The minimum emittance of 2.0 pi mm mrad with a net charge of 0.14 nC/bunch were able to be measured.

  4. Emittance Adapter for a Diffraction Limited Synchrotron Radiation Source

    Energy Technology Data Exchange (ETDEWEB)

    Chao, Alexander Wu; /SLAC; Raimondi, Pantaleo; /Frascati

    2012-03-01

    We investigate the possibility of reaching very small horizontal and vertical emittances inside an undulator in a storage ring, by means of a local exchange of the apparent horizontal and vertical emittances, performed with a combination of skew quadrupoles and one solenoid in a dedicated insertion line in the storage ring. The insertion leaves the ring parameters and its optical properties unaffected. This scheme could greatly relax the emittance requirements for a diffraction limited synchrotron light source. The lattice derivation and design is described.

  5. Performance of fast reactor irradiated fueled emitters at goal burnup

    International Nuclear Information System (INIS)

    UO2-fueled W emitters were examined that had been irradiated to goal burnups of approximately 4 at.% at emitter surface temperatures to 1820 K in a fast reactor to establish their performance for use in thermionic reactors with power levels from tens of kilowatts to multimegawatts. The examinations provided first-time data on structural integrity, dimensional stability, component compatibility, and fuel and fission product behavior. The data are consistent with similar measurements at approximately 2 at.% burnup with the exception of one emitter which breached the W during irradiation

  6. Multi-dimensional beam emittance and β-functions

    International Nuclear Information System (INIS)

    The concept of r.m.s. emittance is extended to the case of several degrees of freedom that are coupled. That multi-dimensional emittance is lower than the product of the emittances attached to each degree of freedom, but is conserved in a linear motion. An envelope-hyperellipsoid is introduced to define the β-functions of the beam envelope. On the contrary of an one-degree of freedom motion, it is emphasized that these envelope functions differ from the amplitude functions of the normal modes of motion as a result of the difference between the Liouville and Lagrange invariants. (author) 4 refs

  7. Ab initio alpha-alpha scattering.

    Science.gov (United States)

    Elhatisari, Serdar; Lee, Dean; Rupak, Gautam; Epelbaum, Evgeny; Krebs, Hermann; Lähde, Timo A; Luu, Thomas; Meißner, Ulf-G

    2015-12-01

    Processes such as the scattering of alpha particles ((4)He), the triple-alpha reaction, and alpha capture play a major role in stellar nucleosynthesis. In particular, alpha capture on carbon determines the ratio of carbon to oxygen during helium burning, and affects subsequent carbon, neon, oxygen, and silicon burning stages. It also substantially affects models of thermonuclear type Ia supernovae, owing to carbon detonation in accreting carbon-oxygen white-dwarf stars. In these reactions, the accurate calculation of the elastic scattering of alpha particles and alpha-like nuclei--nuclei with even and equal numbers of protons and neutrons--is important for understanding background and resonant scattering contributions. First-principles calculations of processes involving alpha particles and alpha-like nuclei have so far been impractical, owing to the exponential growth of the number of computational operations with the number of particles. Here we describe an ab initio calculation of alpha-alpha scattering that uses lattice Monte Carlo simulations. We use lattice effective field theory to describe the low-energy interactions of protons and neutrons, and apply a technique called the 'adiabatic projection method' to reduce the eight-body system to a two-cluster system. We take advantage of the computational efficiency and the more favourable scaling with system size of auxiliary-field Monte Carlo simulations to compute an ab initio effective Hamiltonian for the two clusters. We find promising agreement between lattice results and experimental phase shifts for s-wave and d-wave scattering. The approximately quadratic scaling of computational operations with particle number suggests that it should be possible to compute alpha scattering and capture on carbon and oxygen in the near future. The methods described here can be applied to ultracold atomic few-body systems as well as to hadronic systems using lattice quantum chromodynamics to describe the interactions of

  8. Ab initio alpha-alpha scattering

    Science.gov (United States)

    Elhatisari, Serdar; Lee, Dean; Rupak, Gautam; Epelbaum, Evgeny; Krebs, Hermann; Lähde, Timo A.; Luu, Thomas; Meißner, Ulf-G.

    2015-12-01

    Processes such as the scattering of alpha particles (4He), the triple-alpha reaction, and alpha capture play a major role in stellar nucleosynthesis. In particular, alpha capture on carbon determines the ratio of carbon to oxygen during helium burning, and affects subsequent carbon, neon, oxygen, and silicon burning stages. It also substantially affects models of thermonuclear type Ia supernovae, owing to carbon detonation in accreting carbon-oxygen white-dwarf stars. In these reactions, the accurate calculation of the elastic scattering of alpha particles and alpha-like nuclei—nuclei with even and equal numbers of protons and neutrons—is important for understanding background and resonant scattering contributions. First-principles calculations of processes involving alpha particles and alpha-like nuclei have so far been impractical, owing to the exponential growth of the number of computational operations with the number of particles. Here we describe an ab initio calculation of alpha-alpha scattering that uses lattice Monte Carlo simulations. We use lattice effective field theory to describe the low-energy interactions of protons and neutrons, and apply a technique called the ‘adiabatic projection method’ to reduce the eight-body system to a two-cluster system. We take advantage of the computational efficiency and the more favourable scaling with system size of auxiliary-field Monte Carlo simulations to compute an ab initio effective Hamiltonian for the two clusters. We find promising agreement between lattice results and experimental phase shifts for s-wave and d-wave scattering. The approximately quadratic scaling of computational operations with particle number suggests that it should be possible to compute alpha scattering and capture on carbon and oxygen in the near future. The methods described here can be applied to ultracold atomic few-body systems as well as to hadronic systems using lattice quantum chromodynamics to describe the interactions of

  9. Molecular breast imaging with gamma emitters.

    Science.gov (United States)

    Schillaci, O; Spanu, A; Danieli, R; Madeddu, G

    2013-12-01

    Following a diagnosis of breast cancer (BC), the early detection of local recurrence is important to define appropriate therapeutic strategies and increase the chances of a cure. In fact, despite major progress in surgical treatment, radiotherapy, and chemotherapy protocols, tumor recurrence is still a major problem. Moreover, the diagnosis of recurrence with conventional imaging methods can be difficult as a result of the presence of scar tissue. Molecular breast imaging (MBI) with gamma-ray emitting radiotracers may be very useful in this clinical setting, because it is not affected by the post-therapy morphologic changes. This review summarises the applications of 99mTc-sestamibi and 99mTc-tetrofosmin, the two most employed gamma emitter radiopharmaceuticals for MBI, in the diagnosis of local disease recurrence in patients with BC. The main limitation of MBI using conventional gamma-cameras is the low sensitivity for small BCs. The recent development of hybrid single photon emission computed tomography/computed tomography devices and especially of high-resolution specific breast cameras can improve the detection rate of sub-centimetric malignant lesions. Nevertheless, probably only the large availability of dedicated cameras will allow the clinical acceptance of MBI as useful complementary diagnostic technique in BC recurrence. The possible role of MBI with specific cameras in monitoring the local response of BC to neoadjuvant chemotherapy is also briefly discussed. PMID:24322791

  10. Hafnium carbide nanocrystal chains for field emitters

    International Nuclear Information System (INIS)

    A hafnium carbide (HfC) nanostructure, i.e., HfC nanocrystal chain, was synthesized by a chemical vapor deposition (CVD) method. X-ray diffractometer, field-emission scanning electron microscope, transmission electron microscope, and energy-dispersive X-ray spectrometer were employed to characterize the product. The synthesized one-dimensional (1D) nanostructures with many faceted octahedral nanocrystals possess diameters of tens of nanometers to 500 nm and lengths of a few microns. The chain-like structures possess a single crystalline structure and preferential growth direction along the [1 0 0] crystal orientation. The growth of the chains occurred through the vapor–liquid–solid process along with a negative-feedback mechanism. The field emission (FE) properties of the HfC nanocrystal chains as the cold cathode emitters were examined. The HfC nanocrystal chains display good FE properties with a low turn-on field of about 3.9 V μm−1 and a high field enhancement factor of 2157, implying potential applications in vacuum microelectronics.

  11. Novalike Cataclysmic Variables are Significant Radio Emitters

    CERN Document Server

    Coppejans, Deanne L; Miller-Jones, James C A; Rupen, Michael P; Knigge, Christian; Sivakoff, Gregory R; Groot, Paul J

    2015-01-01

    Radio emission from non-magnetic cataclysmic variables (CVs, accreting white dwarfs) could allow detailed studies of outflows and possibly accretion flows in these nearby, numerous and non-relativistic compact accretors. Up to now, however, very few CVs have been detected in the radio. We have conducted a VLA pilot survey of four close and optically-bright novalike CVs at 6 GHz, detecting three, and thereby doubling the number of radio detections of these systems. RW Sex, V603 Aql and the old nova TT Ari were detected in both of the epochs, while V1084 Her was not detected (to a $3\\sigma$ upper-limit of 7.8 $\\mu\\rm{Jy}\\,\\rm{beam}^{-1}$). These observations clearly show that the sensitivity of previous surveys was typically too low to detect these objects and that non-magnetic CVs can indeed be significant radio emitters. The three detected sources show a range of properties, including flaring and variability on both short ($\\sim$200 s) and longer-term (days) time-scales, as well as circular polarization level...

  12. C-CAP Hawaii 2005 Land Cover

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  13. C-CAP Land Cover, Niihau, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  14. C-CAP Land Cover, Maui, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  15. C-CAP Land Cover, Molokai, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  16. C-CAP Land Cover, Kauai, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  17. C-CAP Land Cover, Lanai, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  18. Circumpolar Active-Layer Permafrost System (CAPS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Circumpolar Active-Layer Permafrost System (CAPS) contains over 100 data sets pertaining to permafrost and frozen ground topics. It also contains detailed...

  19. Naturally-occurring alpha activity

    International Nuclear Information System (INIS)

    In view of the difficulties of assessing the significance of man-made radioactivity it is important to study for comparison the background of natural radioactivity against which the human race has evolved and lives. It is also important to define the present levels of activity so that it will be possible to detect and study as quickly as possible any changes which may occur owing to the release into the environment of new radioactive materials. Moreover, by the study of the behaviour of natural radioactivity light may be shed upon that of the artificially produced isotopes and a number of analogies traced between the two groups. These concepts have led to studies of naturally-occurring radioactive materials alongside a programme of research into fission products in food, water and air, as well as studies of the metabolism of both sets of materials in the human body. Since the last report there has been a useful increase in our knowledge of natural radioactivity in the biosphere, and its levels relative to the new man-made activities. These studies have necessitated technical developments, particularly in the methods of measuring and identifying alpha-ray emitters, to which group many of the more important natural radioactive materials belong

  20. Faddeev calculation of 3 alpha and alpha alpha Lambda systems using alpha alpha resonating-group method kernel

    CERN Document Server

    Fujiwara, Y; Kohno, M; Suzuki, Y; Baye, D; Sparenberg, J M

    2004-01-01

    We carry out Faddeev calculations of three-alpha (3 alpha) and two-alpha plus Lambda (alpha alpha Lambda) systems, using two-cluster resonating-group method kernels. The input includes an effective two-nucleon force for the alpha alpha resonating-group method and a new effective Lambda N force for the Lambda alpha interaction. The latter force is a simple two-range Gaussian potential for each spin-singlet and triplet state, generated from the phase-shift behavior of the quark-model hyperon-nucleon interaction, fss2, by using an inversion method based on supersymmetric quantum mechanics. Owing to the exact treatment of the Pauli-forbidden states between the clusters, the present three-cluster Faddeev formalism can describe the mutually related, alpha alpha, 3 alpha and alpha alpha Lambda systems, in terms of a unique set of the baryon-baryon interactions. For the three-range Minnesota force which describes the alpha alpha phase shifts quite accurately, the ground-state and excitation energies of 9Be Lambda are...

  1. Design and implementation of the CAPS receiver

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In this paper, based on analyses of the Chinese Area Positioning System (CAPS) satellite (GEO satellite) resources and signal properties, the signal power at the port of the receiver antenna is estimated, and the implementation projects are presented for a switching band C to band L CAPS C/A code receiver integrated with GPS receiver suite and for a CAPS dual frequency P code receiver. A microstrip receiving antenna is designed with high sensitivity and wide beam orientation, the RF front end of the C/A code and P code receivers, and a processor is designed for the navigation baseband. A single frequency CAPS C/A code receiver and a CAPS dual frequency P code receiver are built at the same time. A software process flow is provided, and research on relatively key techniques is also conducted, such as signal searching, code loop and carrier loop algorithms, a height assistant algorithm, a dual frequency difference speed measurement technique, a speed measurement technique using a single frequency source with frequency assistance, and a CAPS time correcting algorithm, according to the design frame of the receiver hardware. Research results show that the static plane positioning accuracy of the CAPS C/A code receiver is 20.5-24.6 m, height accuracy is 1.2-12.8 m, speed measurement accuracy is 0.13-0.3 m/s, dynamic plane positioning accuracy is 24.4 m, height accuracy is 3.0 m, and speed measurement accuracy is 0.24 m/s. In the case of C/A code, the timing accuracy is 200 ns, and it is also shown that the positioning accuracy of the CAPS precise code receiver (1σ ) is 5 m from south to north, and 0.8 m from east to west. Finally, research on positioning accuracy is also conducted.

  2. UNDERSTANDING FARMERS’ RESPONSES TO CAP REFORM

    OpenAIRE

    Menozzi, Davide; Fioravanzi, Martina; Donati, Michele

    2014-01-01

    The 2014-2020 Common Agricultural Policy (CAP) reform defines new rules for farmers including regionalization, crop diversification and ecological focus area (EFA). This paper aims to evaluate farmers’ intention to modify their behaviour because of the CAP reform, using the Theory of Planned Behaviour (TPB). A questionnaire was submitted to 71 Italian durum wheat producers assessing their intention to change durum wheat surface and to maintain as EFA part of the arable land. Subjective norms ...

  3. Corrective action program (CAP) in United States

    International Nuclear Information System (INIS)

    The Corrective Action Process (CAP) is one of the most important key issues on the Nuclear Reactor Safety. The experiences on the nuclear power plant operations, including safety culture, maintenance, and so on, should be continuously evaluated and influenced to the KAIZEN (improvement) of the NPP operations. The review of the CAP system in US will be useful for the NPP safety in Japan. (author)

  4. High brightness symmetric emittance rf photoinjector preliminary design report

    International Nuclear Information System (INIS)

    A preliminary design for a high bunch charge (8 nC), low emittance (z = 1 mm. Electrical and beam dynamical aspects of the photoinjector design are presented. A description of the proposed experimental program is included

  5. Recent developments of low-emittance electron gun for accelerator

    International Nuclear Information System (INIS)

    Recent developments of low-emittance electron guns for accelerator are reviewed. In the accelerator field, DC biased triode thermionic gun (Pierce type gun) has been widely used and is still conventional. On the other hand, because of strong demands on the high brightness electron beam by FEL and other advanced accelerator concepts based on linear accelerator, the low emittance beam generation becomes one of the most important issue in the accelerator science. The R and D effort is 'accelerated' by two technological innovations, photo-cathode and RF gun. They made a large improvement on the beam emittance. After the explanations on the technical and physical aspects of the low emittance electron beam generation, advanced electron sources for accelerators are reviewed. (author)

  6. Transverse emittance measurement at REGAE via a solenoid scan

    Energy Technology Data Exchange (ETDEWEB)

    Hachmann, Max

    2012-12-15

    The linear accelerator REGAE at DESY produces short and low charged electron bunches, on the one hand to resolve the excitation transitions of atoms temporally by pump probe electron diffraction experiments and on the other hand to investigate principal mechanisms of laser plasma acceleration. For both cases a high quality electron beam is required. A quantity to rate the beam quality is the beam emittance. In the course of this thesis transverse emittance measurements by a solenoid scan could be realized and beyond that an improved theoretical description of a solenoid was successful. The foundation of emittance measurements are constituted by theoretical models which describe the envelope of a beam. Two different models were derived. The first is an often used model to determine the transverse beam emittance without considering space charge effects. More interesting and challenging was the development of an envelope model taking space charge effects into account. It is introduced and cross checked with measurements and simulations.

  7. Nanostructure-induced distortion in single-emitter microscopy

    CERN Document Server

    Lim, Kangmook; Fourkas, John; Shapiro, Benjamin; Waks, Edo

    2016-01-01

    Single-emitter microscopy has emerged as a promising method of imaging nanostructures with nanoscale resolution. This technique uses the centroid position of an emitters far-field radiation pattern to infer its position to a precision that is far below the diffraction limit. However, nanostructures composed of high-dielectric materials such as noble metals can distort the far-field radiation pattern. Nanoparticles also exhibit a more complex range of distortions, because in addition to introducing a high dielectric surface, they also act as efficient scatterers. Thus, the distortion effects of nanoparticles in single-emitter microscopy remains poorly understood. Here we demonstrate that metallic nanoparticles can significantly distort the accuracy of single-emitter imaging at distances exceeding 300 nm. We use a single quantum dot to probe both the magnitude and the direction of the metallic nanoparticle-induced imaging distortion and show that the diffraction spot of the quantum dot can shift by more than 35...

  8. Non-blinking single-photon emitters in silica

    Science.gov (United States)

    Rabouw, Freddy T.; Cogan, Nicole M. B.; Berends, Anne C.; Stam, Ward van der; Vanmaekelbergh, Daniel; Koenderink, A. Femius; Krauss, Todd D.; Donega, Celso de Mello

    2016-01-01

    Samples for single-emitter spectroscopy are usually prepared by spin-coating a dilute solution of emitters on a microscope cover slip of silicate based glass (such as quartz). Here, we show that both borosilicate glass and quartz contain intrinsic defect colour centres that fluoresce when excited at 532 nm. In a microscope image the defect emission is indistinguishable from spin-coated emitters. The emission spectrum is characterised by multiple peaks with the main peak between 2.05 and 2.20 eV, most likely due to coupling to a silica vibration with an energy that varies between 160 and 180 meV. The defects are single-photon emitters, do not blink, and have photoluminescence lifetimes of a few nanoseconds. Photoluminescence from such defects may previously have been misinterpreted as originating from single nanocrystal quantum dots. PMID:26892489

  9. Localization of Narrowband Single Photon Emitters in Nanodiamonds.

    Science.gov (United States)

    Bray, Kerem; Sandstrom, Russell; Elbadawi, Christopher; Fischer, Martin; Schreck, Matthias; Shimoni, Olga; Lobo, Charlene; Toth, Milos; Aharonovich, Igor

    2016-03-23

    Diamond nanocrystals that host room temperature narrowband single photon emitters are highly sought after for applications in nanophotonics and bioimaging. However, current understanding of the origin of these emitters is extremely limited. In this work, we demonstrate that the narrowband emitters are point defects localized at extended morphological defects in individual nanodiamonds. In particular, we show that nanocrystals with defects such as twin boundaries and secondary nucleation sites exhibit narrowband emission that is absent from pristine individual nanocrystals grown under the same conditions. Critically, we prove that the narrowband emission lines vanish when extended defects are removed deterministically using highly localized electron beam induced etching. Our results enhance the current understanding of single photon emitters in diamond and are directly relevant to fabrication of novel quantum optics devices and sensors. PMID:26937848

  10. Beam Emittance Measurement for PLS-II Linac

    CERN Document Server

    Lee, Byung-Joon; Park, Chong do; Chunjarean, SomJai; Kim, Changbum

    2016-01-01

    The PLS-II has a 100 MeV pre-injector for the 3 GeV Linac. A thermionic gun produces electron charge of 200 pC with a bunch duration of 500 ps by a 250 ps triggering pulser. At the pre-injector, one of the most important beam parameters to identify the beam quality is a transverse emittance of electron bunches. Therefore we measure the beam emittance and twiss functions at 100 MeV in order to match the beam optics to beam transport line and go through it to the storage ring. To get the transverse emittance measurement, well-known technique, quadrupole scan, is used at the pre-injector. The emittance were 0.591 mm-mrad in horizontal and 0.774 mm-mrad in vertical direction.

  11. CSR-induced emittance growth in achromats: Linear formalism revisited

    Energy Technology Data Exchange (ETDEWEB)

    Venturini, M.

    2015-09-11

    We review the R-matrix formalism used to describe Coherent Synchrotron Radiation (CSR)-induced projected emittance growth in electron beam transport lines and establish the connection with a description in terms of the dispersion-invariant function.

  12. CSR-induced emittance growth in achromats: Linear formalism revisited

    Science.gov (United States)

    Venturini, M.

    2015-09-01

    We review the R-matrix formalism used to describe Coherent Synchrotron Radiation (CSR)-induced projected emittance growth in electron beam transport lines and establish the connection with a description in terms of the dispersion-invariant function.

  13. What future for quantum dot-based light emitters?

    Science.gov (United States)

    Nurmikko, Arto

    2015-12-01

    Synthesis of semiconductor colloidal quantum dots by low-cost, solution-based methods has produced an abundance of basic science. Can these materials be transformed to high-performance light emitters to disrupt established photonics technologies, particularly semiconductor lasers?

  14. Localization of narrowband single photon emitters in nanodiamonds

    CERN Document Server

    Bray, Kerem; Elbadawi, Christopher; Fischer, Martin; Schreck, Matthias; Shimoni, Olga; Lobo, Charlene; Toth, Milos; Aharonovich, Igor

    2016-01-01

    Diamond nanocrystals that host room temperature narrowband single photon emitters are highly sought after for applications in nanophotonics and bio-imaging. However, current understanding of the origin of these emitters is extremely limited. In this work we demonstrate that the narrowband emitters are point defects localized at extended morphological defects in individual nanodiamonds. In particular, we show that nanocrystals with defects such as twin boundaries and secondary nucleation sites exhibit narrowband emission that is absent from pristine individual nanocrystals grown under the same conditions. Critically, we prove that the narrowband emission lines vanish when extended defects are removed deterministically using highly localized electron beam induced etching. Our results enhance the current understanding of single photon emitters in diamond, and are directly relevant to fabrication of novel quantum optics devices and sensors.

  15. Innovative energy efficient low-voltage electron beam emitters

    International Nuclear Information System (INIS)

    Advanced electron beams (AEB) has developed a modular, low voltage (80-125 keV), high beam current (up to 40 ma), electron emitter with typically 25 cm of beam width, that is housed in an evacuated, returnable chamber that is easy to plug in and connect. The latest in nanofabrication enables AEB to use an ultra-thin beam window. The power supply for AEB's emitter is based on solid-state electronics. This combination of features results in a remarkable electrical efficiency. AEB's electron emitter relies on a touch screen, computer control system. With 80 μm of unit density beam penetration, AEB's electron emitter has gained market acceptance in the curing of opaque, pigmented inks and coatings used on flexible substrates, metals and fiber composites and in the curing of adhesives in foil based laminates

  16. Emitter Design and Numerical Simulation Based on the Extenics Theory

    Directory of Open Access Journals (Sweden)

    Jiang Fan

    2014-05-01

    Full Text Available In order to improve the performance of emitter, the extenics theory is introduced, whose divergent thinking is used to resolve the conflict of anti-clogging and energy dissipation and a new structure is proposed. The wide triangular areas are designed to reduce the flow rate behind of the each orifice and be easy to precipitation of impurities. The orifices are set to gradually decrease water kinetic energy and the flow channel is designed to be dismantle. The numerical simulation technology is used to analyze the internal flow field of emitter, the flow field results show that the improved emitter has great effect of energy dissipation and anti-clogging. As the same time, the structure of emitter is optimized and L1 = 31 mm, L2 = 21 mm, L3 = 8 mm and L4 = 5 mm are the optimization size values.

  17. The emittance of space radiator materials measured at elevated temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Mirtich, M.J. [Lewis Research Center, Cleveland, OH (United States); DiFilippo, F. [Case Western Reserve Univ., Cleveland, OH (United States); Barry, J.; Kussmaul, M. [Cleveland State Univ., OH (United States)

    1994-09-01

    The spectral emittances of textured space radiator materials between 1.7 and 14.7 {mu}m have been evaluated at room temperature and elevated temperature (630{degrees}C) in air. Heating in air caused a permanent increase in spectral emittance for all materials tested: HCl/ion beam textured 304 stainless steel, untextured Ti (6 percent Al, 4 percent V), and sandblasted Ti (6 percent Al, 4 percent V). Changes in the surface chemistry and/or surface morphology of these materials were also observed. Elevated temperature spectral emittance was measured in an argon atmosphere and compared to the measurements in air. Similarity between the room temperature and elevated temperature spectral emittance measurements was also investigated, and limited agreement was found.

  18. Transverse emittance measurement at REGAE via a solenoid scan

    International Nuclear Information System (INIS)

    The linear accelerator REGAE at DESY produces short and low charged electron bunches, on the one hand to resolve the excitation transitions of atoms temporally by pump probe electron diffraction experiments and on the other hand to investigate principal mechanisms of laser plasma acceleration. For both cases a high quality electron beam is required. A quantity to rate the beam quality is the beam emittance. In the course of this thesis transverse emittance measurements by a solenoid scan could be realized and beyond that an improved theoretical description of a solenoid was successful. The foundation of emittance measurements are constituted by theoretical models which describe the envelope of a beam. Two different models were derived. The first is an often used model to determine the transverse beam emittance without considering space charge effects. More interesting and challenging was the development of an envelope model taking space charge effects into account. It is introduced and cross checked with measurements and simulations.

  19. Intelligent Variable Emittance Panels Using New, ?True? Solid Electrolyte Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This firm has, in ongoing work in collaboration with the Air Force, NASA and JPL, developed a unique Variable Emittance technology based on the electrochromism of...

  20. Optimization of Metamaterial Selective Emitters for Use in Thermophotovoltaic Applications

    Science.gov (United States)

    Pfiester, Nicole A.

    The increasing costs of fossil fuels, both financial and environmental, has motivated many to look into sustainable energy sources. Thermophotovoltaics (TPVs), specialized photovoltaic cells focused on the infrared range, offer an opportunity to achieve both primary energy capture, similar to traditional photovoltaics, as well as secondary energy capture in the form of waste heat. However, to become a feasible energy source, TPV systems must become more efficient. One way to do this is through the development of selective emitters tailored to the bandgap of the TPV diode in question. This thesis proposes the use of metamaterial emitters as an engineerable, highly selective emitter that can withstand the temperatures required to collect waste heat. Metamaterial devices made of platinum and a dielectric such as alumina or silicon nitride were initially designed and tested as perfect absorbers. High temperature robustness testing demonstrates the device's ability to withstand the rigors of operating as a selective emitter.

  1. Optimization of the emittance of electrons (positrons) storage rings

    International Nuclear Information System (INIS)

    An important parameter of the source characteristics of a synchrotron radiation facility, is the beam emittance. The general structure presently adopted, is of the achromatic arc, or adapted dispersion type. This structure allows analytical treatment of dispersion and β function in the arcs, and then, the minimization of the dimension invariant. Practical formulae are given, allowing scaling of momentum compaction factor, minimum emittance limit and β value in the magnets. Limitations in chromaticity correction possibilities are also discussed

  2. Internal emitter limits for iodine, radium and radon daughters

    Energy Technology Data Exchange (ETDEWEB)

    Schlenker, R.A.

    1984-08-15

    This paper identifies some of the issues which arise in the consideration of the derivation of new limits on exposure to internal emitters. Basic and secondary radiation protection limits are discussed. Terms are defined and applied to the limitation of risk from stochastic effects. Non-stochastic data for specific internal emitters (/sup 131/I and the radium isotopes) are presented. Emphasis is placed on the quantitative aspects of the limit setting problem. 65 references, 2 figures, 12 tables.

  3. Evaluation of Production Reactions for Medically Important Positron Emitters

    International Nuclear Information System (INIS)

    Research activities of direct relevance to the CRP are based on the proposed evaluation of a range of medically important positron emitters. The production and assessment of excitation functions for various novel positron emitters has been recommended for investigation and quantification. Hence, the research group at Lahore has developed an evaluation methodology for charged-particle induced reactions. The main steps of the adopted procedure are listed

  4. Radiation swelling of emitters in nuclear thermoemission converters

    Energy Technology Data Exchange (ETDEWEB)

    Novikov, V.S.

    1976-01-01

    A mathematical model is proposed for the radiation swelling of emitters in nuclear thermoemission converters. This model takes into account the temperature gradients and concentrations of uranium decay products along the emitter cross-section, and also the external pressure and the simultaneous action of various mechanisms of swelling. In the particular case of swelling caused by an increase in gaseous pores, a solution is obtained for this model that is in qualitative agreement with the experiment data.

  5. Emittance growth due to dipole ripple and sextupole

    International Nuclear Information System (INIS)

    Ripple in the power supplies for storage ring magnets can have adverse effects on the circulating beams: orbit distortion and emittance growth from dipole ripple, tune modulation and dynamic aperture reduction from quadrupole ripple, etc. In this paper, the authors study the effects of ripple in the horizontal bending field of the SSC in the presence of nonlinearity, in particular, the growth in beam emittance

  6. Fabrication of VO2-based multilayer structure with variable emittance

    International Nuclear Information System (INIS)

    Highlights: • Multilayer structures consisted of VO2 layer, HfO2 layer and Ag layer. • Influence of VO2 and HfO2 layer thickness on the emittance variability was studied. • Emittance variation of 0.55 and transition temperature (Tc) of 58 °C was obtained. • Multilayer structures with W-doped VO2 film were deposited. • Influence of W doping concentration on emittance variability was investigated. - Abstract: VO2 film holds promise for smart radiation device (SRD) use because of its infrared reflection change through the semiconductor-to-metal transition (SMT). In present study, a multilayer structure which consisted of VO2 layer, HfO2 layer and Ag layer was fabricated to achieve variable emittance based on the principle of reflection filter and SMT of VO2. It was found that with optimal 50 nm-thick VO2 layer, emittance of the multilayer structure could reversibly change from 0.13 at 30 °C to 0.68 at 80 °C with emittance variability of 0.55. Emittance hysteresis loop with transition temperature (Tc) of 58 °C and narrow width of 4 °C was obtained. Finally, multilayer structures with W-doped VO2 films were deposited and transition temperature decreased from 58 to 5 °C as W doping concentration increased from 0% to 3%, with Tc decreasing efficiency of −17.2 °C/at%. However, W doping also led to increased low temperature infrared absorption of VO2 film, which resulted in decreased emittance variability for the multilayer structure, from 0.55 to 0.37 as the W doping concentration in VO2 layer increase from 0% to 3%

  7. A Novel Depletion-Mode MOS Gated Emitter Shorted Thyristor

    Institute of Scientific and Technical Information of China (English)

    张鹤鸣; 戴显英; 张义门; 马晓华; 林大松

    2000-01-01

    A Novel MOS-gated thyristor, depletion-mode MOS gated emitter shorted thyristor (DMST),and its two structures are proposed. In DMST,the channel of depletion-mode MOS makes the thyristor emitter-based junction inherently short. The operation of the device is controlled by the interruption and recovery of the depletion-mode MOS P channel. The perfect properties have been demonstrated by 2-D numerical simulations and the tests on the fabricated chips.

  8. Internal emitter limits for iodine, radium and radon daughters

    International Nuclear Information System (INIS)

    This paper identifies some of the issues which arise in the consideration of the derivation of new limits on exposure to internal emitters. Basic and secondary radiation protection limits are discussed. Terms are defined and applied to the limitation of risk from stochastic effects. Non-stochastic data for specific internal emitters (131I and the radium isotopes) are presented. Emphasis is placed on the quantitative aspects of the limit setting problem. 65 references, 2 figures, 12 tables

  9. Study of ultra-low emittance design for SPEAR3

    Energy Technology Data Exchange (ETDEWEB)

    Wang, M. -H.; Huang, X.; Safranek, J.; /SLAC

    2015-09-17

    Since its 2003 construction, the SPEAR3 synchrotron light source at SLAC has continuously improved its performance by raising beam current, top-off injection, and smaller emittance. This makes SPEAR3 one of the most productive light sources in the world. Now, to further enhance the performance of SPEAR3, we are looking into the possibility of converting SPEAR3 to an ultra-low emittance storage ring within its site constraint.

  10. Final report for Frequency selective surfaces for rugged thermophotovoltaic emitters

    Energy Technology Data Exchange (ETDEWEB)

    Daly, James

    2001-04-05

    Ion Optics created an array of regularly spaced holes in a thin conductive surface film on a dielectric substrate. When heated, this pattern behaved as a selective emitter, with more than 50% of total radiation in a well-defined peak with a center frequency determined by geometrical spacing. Peak wavelength did not alter with change in temperature, and materials easily survived 10 hours at 1000 C in air. The selective emitter will increase efficiency of thermophotovoltaic power converters.

  11. High Precision Measurement of Muon Beam Emittance Reduction in MICE

    CERN Document Server

    Rogers, Chris

    2005-01-01

    Muon ionization cooling, an essential ingredient of a neutrino factory, will be demonstrated for the first time by the MICE experiment. The central part of MICE consists of a short section of a neutrino factory cooling channel and the emittance reduction achieved in this experiment is quite modest, 10% to 15%. In order to extrapolate the performance of a full cooling channel from these values, it is crucial for MICE to achieve an emittance measurement accuracy of 10

  12. Remote system for measurement of radon alpha emitter for population safety guards

    International Nuclear Information System (INIS)

    The objective of this research project is to study the OSL properties for high doses of dosemeters traditionally applied in thermoluminescent dosimetry (TL), as CaF2: Dy (TLD 200) and CaF2: Mn (TLD 400), and thus verify the applicability of OSL technique in high-dose dosimetry

  13. Quality assurance exercise for estimating low-levels of alpha emitters in spiked mineral matrix

    International Nuclear Information System (INIS)

    IAEA organized proficiency test on the determination of α and β -emitting radionuclides within the frame of the technical Cooperation project: Environmental Radiation Monitoring and Regional Data Base to evaluate the analytical performance of various laboratories from different Asian countries. This paper summarises the performance evaluation of the trace analysis laboratory of Environmental Assessment Division, Bhabha Atomic Research Centre

  14. New lines for action in the treatment of nuclear power plants produced by alpha emitters

    International Nuclear Information System (INIS)

    Today, as a result of recent events on issues such as energy security and environmental protection, we are witnessing a resurgence of interest in nuclear power. To support this development has also initiated a nuclear renaissance in parallel on Education, Training and Knowledge Management in the nuclear field.

  15. A bone marrow toxicity model for 223Ra alpha-emitter radiopharmaceutical therapy

    Science.gov (United States)

    Hobbs, Robert F.; Song, Hong; Watchman, Christopher J.; Bolch, Wesley E.; Aksnes, Anne-Kirsti; Ramdahl, Thomas; Flux, Glenn D.; Sgouros, George

    2012-05-01

    Ra-223, an α-particle emitting bone-seeking radionuclide, has recently been used in clinical trials for osseous metastases of prostate cancer. We investigated the relationship between absorbed fraction-based red marrow dosimetry and cell level-dosimetry using a model that accounts for the expected localization of this agent relative to marrow cavity architecture. We show that cell level-based dosimetry is essential to understanding potential marrow toxicity. The GEANT4 software package was used to create simple spheres representing marrow cavities. Ra-223 was positioned on the trabecular bone surface or in the endosteal layer and simulated for decay, along with the descendants. The interior of the sphere was divided into cell-size voxels and the energy was collected in each voxel and interpreted as dose cell histograms. The average absorbed dose values and absorbed fractions were also calculated in order to compare those results with previously published values. The absorbed dose was predominantly deposited near the trabecular surface. The dose cell histogram results were used to plot the percentage of cells that received a potentially toxic absorbed dose (2 or 4 Gy) as a function of the average absorbed dose over the marrow cavity. The results show (1) a heterogeneous distribution of cellular absorbed dose, strongly dependent on the position of the cell within the marrow cavity; and (2) that increasing the average marrow cavity absorbed dose, or equivalently, increasing the administered activity resulted in only a small increase in potential marrow toxicity (i.e. the number of cells receiving more than 4 or 2 Gy), for a range of average marrow cavity absorbed doses from 1 to 20 Gy. The results from the trabecular model differ markedly from a standard absorbed fraction method while presenting comparable average dose values. These suggest that increasing the amount of radioactivity may not substantially increase the risk of toxicity, a result unavailable to the absorbed fraction method of dose calculation.

  16. Electromagnetic compatibility of implantable neurostimulators to RFID emitters

    Science.gov (United States)

    2011-01-01

    Background The objective of this study is to investigate electromagnetic compatibility (EMC) of implantable neurostimulators with the emissions from radio frequency identification (RFID) emitters. Methods Six active implantable neurostimulators with lead systems were tested for susceptibility to electromagnetic fields generated by 22 RFID emitters. These medical devices have been approved for marketing in the U.S. for a number of intended uses that include: epilepsy, depression, incontinence, Parkinsonian tremor and pain relief. Each RFID emitter had one of the following carrier frequencies: 125 kHz, 134 kHz, 13.56 MHz, 433 MHz, 915 MHz and 2.45 GHz Results The test results showed the output of one of the implantable neurostimulators was inhibited by 134 kHz RFID emitter at separation distances of 10 cm or less. The output of the same implantable neurostimulator was also inhibited by another 134 kHz RFID emitter at separation distances of 10 cm or less and also showed inconsistent pulsing rate at a separation distance of 15 cm. Both effects occurred during and lasted through out the duration of the exposure. Conclusions The clinical significance of the effects was assessed by a clinician at the U.S. Food and Drug Administration. The effects were determined to be clinically significant only if they occurred for extended period of time. There were no observed effects from the other 5 implantable neurostimulators or during exposures from other RFID emitters. PMID:21658266

  17. Electromagnetic compatibility of implantable neurostimulators to RFID emitters

    Directory of Open Access Journals (Sweden)

    Guag Joshua W

    2011-06-01

    Full Text Available Abstract Background The objective of this study is to investigate electromagnetic compatibility (EMC of implantable neurostimulators with the emissions from radio frequency identification (RFID emitters. Methods Six active implantable neurostimulators with lead systems were tested for susceptibility to electromagnetic fields generated by 22 RFID emitters. These medical devices have been approved for marketing in the U.S. for a number of intended uses that include: epilepsy, depression, incontinence, Parkinsonian tremor and pain relief. Each RFID emitter had one of the following carrier frequencies: 125 kHz, 134 kHz, 13.56 MHz, 433 MHz, 915 MHz and 2.45 GHz Results The test results showed the output of one of the implantable neurostimulators was inhibited by 134 kHz RFID emitter at separation distances of 10 cm or less. The output of the same implantable neurostimulator was also inhibited by another 134 kHz RFID emitter at separation distances of 10 cm or less and also showed inconsistent pulsing rate at a separation distance of 15 cm. Both effects occurred during and lasted through out the duration of the exposure. Conclusions The clinical significance of the effects was assessed by a clinician at the U.S. Food and Drug Administration. The effects were determined to be clinically significant only if they occurred for extended period of time. There were no observed effects from the other 5 implantable neurostimulators or during exposures from other RFID emitters.

  18. Validated Analytical Model of a Pressure Compensation Drip Irrigation Emitter

    Science.gov (United States)

    Shamshery, Pulkit; Wang, Ruo-Qian; Taylor, Katherine; Tran, Davis; Winter, Amos

    2015-11-01

    This work is focused on analytically characterizing the behavior of pressure-compensating drip emitters in order to design low-cost, low-power irrigation solutions appropriate for off-grid communities in developing countries. There are 2.5 billion small acreage farmers worldwide who rely solely on their land for sustenance. Drip, compared to flood, irrigation leads to up to 70% reduction in water consumption while increasing yields by 90% - important in countries like India which are quickly running out of water. To design a low-power drip system, there is a need to decrease the pumping pressure requirement at the emitters, as pumping power is the product of pressure and flow rate. To efficiently design such an emitter, the relationship between the fluid-structure interactions that occur in an emitter need to be understood. In this study, a 2D analytical model that captures the behavior of a common drip emitter was developed and validated through experiments. The effects of independently changing the channel depth, channel width, channel length and land height on the performance were studied. The model and the key parametric insights presented have the potential to be optimized in order to guide the design of low-pressure, clog-resistant, pressure-compensating emitters.

  19. A novel self-guided approach to alpha activity training.

    Science.gov (United States)

    van Boxtel, Geert J M; Denissen, Ad J M; Jäger, Mark; Vernon, David; Dekker, Marian K J; Mihajlović, Vojkan; Sitskoorn, Margriet M

    2012-03-01

    Fifty healthy participants took part in a double-blind placebo-controlled study in which they were either given auditory alpha activity (8-12Hz) training (N=18), random beta training (N=12), or no training at all (N=20). A novel wireless electrode system was used for training without instructions, involving water-based electrodes mounted in an audio headset. Training was applied approximately at central electrodes. Post-training measurement using a conventional full-cap EEG system revealed a 10% increase in alpha activity at posterior sites compared to pre-training levels, when using the conventional index of alpha activity and a non-linear regression fit intended to model individual alpha frequency. This statistically significant increase was present only in the group that received the alpha training, and remained evident at a 3 month follow-up session, especially under eyes open conditions where an additional 10% increase was found. In an exit interview, approximately twice as many participants in the alpha training group (53%) mentioned that the training was relaxing, compared to those in either the beta (20%) or no training (21%) control groups. Behavioural measures of stress and relaxation were indicative of effects of alpha activity training but failed to reach statistical significance. These results are discussed in terms of a lack of statistical power. Overall, results suggest that self-guided alpha activity training using this novel system is feasible and represents a step forward in the ease of instrumental conditioning of brain rhythms. PMID:22119661

  20. Barium Depletion in Hollow Cathode Emitters

    Science.gov (United States)

    Polk, James E.; Capece, Angela M.; Mikellides, Ioannis G.; Katz, Ira

    2009-01-01

    The effect of tungsten erosion, transport and redeposition on the operation of dispenser hollow cathodes was investigated in detailed examinations of the discharge cathode inserts from an 8200 hour and a 30,352 hour ion engine wear test. Erosion and subsequent re-deposition of tungsten in the electron emission zone at the downstream end of the insert reduces the porosity of the tungsten matrix, preventing the ow of barium from the interior. This inhibits the interfacial reactions of the barium-calcium-aluminate impregnant with the tungsten in the pores. A numerical model of barium transport in the internal xenon discharge plasma shows that the barium required to reduce the work function in the emission zone can be supplied from upstream through the gas phase. Barium that flows out of the pores of the tungsten insert is rapidly ionized in the xenon discharge and pushed back to the emitter surface by the electric field and drag from the xenon ion flow. This barium ion flux is sufficient to maintain a barium surface coverage at the downstream end greater than 0.6, even if local barium production at that point is inhibited by tungsten deposits. The model also shows that the neutral barium pressure exceeds the equilibrium vapor pressure of the impregnant decomposition reaction over much of the insert length, so the reactions are suppressed. Only a small region upstream of the zone blocked by tungsten deposits is active and supplies the required barium. These results indicate that hollow cathode failure models based on barium depletion rates in vacuum dispenser cathodes are very conservative.

  1. Silicon Carbide Emitter Turn-Off Thyristor

    Directory of Open Access Journals (Sweden)

    Jun Wang

    2008-01-01

    Full Text Available A novel MOS-controlled SiC thyristor device, the SiC emitter turn-off thyristor (ETO is a promising technology for future high-voltage switching applications because it integrates the excellent current conduction capability of a SiC thyristor with a simple MOS-control interface. Through unity-gain turn-off, the SiC ETO also achieves excellent Safe Operation Area (SOA and faster switching speeds than silicon ETOs. The world's first 4.5-kV SiC ETO prototype shows a forward voltage drop of 4.26 V at 26.5 A/cm2 current density at room and elevated temperatures. Tested in an inductive circuit with a 2.5 kV DC link voltage and a 9.56-A load current, the SiC ETO shows a fast turn-off time of 1.63 microseconds and a low 9.88 mJ turn-off energy. The low switching loss indicates that the SiC ETO could operate at about 4 kHz if 100 W/cm2 conduction and the 100 W/cm2 turn-off losses can be removed by the thermal management system. This frequency capability is about 4 times higher than 4.5-kV-class silicon power devices. The preliminary demonstration shows that the SiC ETO is a promising candidate for high-frequency, high-voltage power conversion applications, and additional developments to optimize the device for higher voltage (>5 kV and higher frequency (10 kHz are needed.

  2. Effect of water alpha radiolysis on the spent nuclear fuel UO2 matrix alteration

    International Nuclear Information System (INIS)

    Leaching experiments with solution renewal were carried out on UO2 pellets doped with alpha emitters (238/239Pu) to quantify the impact of alpha irradiation on UO2 matrix alteration. Three batches of doped UO2 pellets with different alpha flux levels were studied as well as spent fuel fragments. Interim storage in air of UO2 pellets doped with alpha emitters results in variations of the UO2 surface reactivity, which depends on the alpha particle flux at the interface and on the interim storage duration. The variation in the surface reactivity and the greater uranium release following interim storage cannot be attributed to the effect of alpha radiolysis in aerated media since the uranium release tends toward the same value after several leaching cycles for the doped UO2 pellet batches and spent fuel. However, leaching experiments performed in deaerated media after annealing the samples and pre-leaching the surface suggest that alpha radiolysis does indeed affect the dissolution, which varies with the flux at the UO2/water interface. (authors)

  3. Gross alpha/beta measurements in water samples using liquid scintillation counter

    International Nuclear Information System (INIS)

    Liquid scintillation techniques provide the detection and quantification of alpha and beta emitters in aqueous sample. Liquid Scintillation Counter (LSC) techniques using Pulse Decay Analysis (PDA) allow counting of alpha and beta radiation in the same sample simultaneously. PDA uses special pulse decay time discrimination electronics to differentiate alpha pulses from beta pulses in a liquid scintillator. In this experiment, Packard Tricarb 2770 TR-SL LSC has been used. Ultima Gold LLT produced by Packard Instrument Company was used as the liquid scintillator. The optimum counting parameters and Pulse Decay Discriminator (PDD) settings were provided for the best alpha and beta separation. PDD was verified by counting a pure alpha ''2''4''1Am and a pure beta ''3''6Cl. Spill of beta in alpha and alpha in beta was found around 0.1% at the optimum discriminator setting of 139. The counting efficiencies were 100% and 97% for alpha and beta counting respectively. Water samples were pre-concentrated to achieve the Turkish maximum permissible levels of 0.037 BqL''-''1 for gross alpha radioactivity and 0.37 BqL''-''1 for gross beta radioactivity in drinking water. After counting, the alpha and beta spill corrections were made and the gross alpha and beta radioactivities were calculated. LSC method results were compared with the gas flow proportional counters

  4. Review of alpha_s determinations

    CERN Document Server

    Pich, Antonio

    2013-01-01

    The present knowledge on the strong coupling is briefly summarized. The most precise determinations of alpha_s, at different energies, are reviewed and compared at the Z mass scale, using the predicted QCD running. The impressive agreement achieved between experimental measurements and theoretical predictions constitutes a beautiful and very significant test of Asymptotic Freedom, establishing QCD as the fundamental theory of the strong interaction. The world average value of the strong coupling is found to be alpha_s(M_Z^2)= 0.1186 \\pm 0.0007.

  5. Decay properties of /sup 186/Pb and the lead alpha-decay rate anomaly

    Energy Technology Data Exchange (ETDEWEB)

    Toth, K.S.; Ellis-Akovali, Y.A.; Bingham, C.R.; Moltz, D.M.; Carter, H.K.; Mlekodaj, R.L.; Spejewski, E.H.; Sousa, D.C.

    1984-01-01

    Alpha-decay transitions between ground states of doubly-even nuclei are taken to represent unhindered decays. Reduced widths for these s-wave transitions behave in a regular fashion as a function of both neutron and atomic number. They are largest for nuclei two or four particles beyond a closed shell (with sharp minima at the shell) and they then decrease as the next closure is approached. The s-wave widths for /sup 186/ /sup 188/ /sup 190/ /sup 192/Pb, however, have been reported to behave anomalously, i.e., they purportedly increase by a factor of 30 between /sup 186/Pb (N = 104) and /sup 192/Ob (N = 110) instead of decreasing as one nears N = 126. Theoretical calculations have not reproduced this unusual behavior. The (electron-capture (EC) + ..beta../sup +/) strengths were deduced from K x-ray intensities. A number of corrections are involved in such determinations. We undertook the investigation of the (EC + ..beta../sup +/) decay schemes of these neutron-deficient lead isotopes, in conjunction with studies of their ..cap alpha..-decay properties, to obtain more reliable ..cap alpha..-branching ratios. Herein we present new information on /sup 186/Pb and discuss the partial ..cap alpha.. half-lives for /sup 192/Pb, /sup 190/Pb, /sup 188/Pb, and /sup 186/Pb together with ..cap alpha..-decay rates for even-even nuclei with Z greater than or equal to 78.

  6. Electro-bioremediation of Contaminated Sediment by Electrode Enhanced Capping

    OpenAIRE

    Yan, Fei; Reible, Danny

    2015-01-01

    In-situ capping often eliminates or slows natural degradation of hydrocarbon due to the reducing conditions in the sediments. The purpose of this research was to demonstrate a reactive capping technique, an electrode enhanced cap, to produce favorable conditions for hydrocarbon degradation and evaluate this reactive capping technique for contaminated sediment remediation. Two graphite electrodes were placed horizontally at different layers in a cap and connected to external power of 2 V. Redo...

  7. How does the antagonism between capping and anti-capping proteins affect actin network dynamics?

    International Nuclear Information System (INIS)

    Actin-based cell motility is essential to many biological processes. We built a simplified, three-dimensional computational model and subsequently performed stochastic simulations to study the growth dynamics of lamellipodia-like branched networks. In this work, we shed light on the antagonism between capping and anti-capping proteins in regulating actin dynamics in the filamentous network. We discuss detailed mechanisms by which capping and anti-capping proteins affect the protrusion speed of the actin network and the rate of nucleation of filaments. We computed a phase diagram showing the regimes of motility enhancement and inhibition by these proteins. Our work shows that the effects of capping and anti-capping proteins are mainly transmitted by modulation of the filamentous network density and local availability of monomeric actin. We discovered that the combination of the capping/anti-capping regulatory network with nucleation-promoting proteins introduces robustness and redundancy in cell motility machinery, allowing the cell to easily achieve maximal protrusion speeds under a broader set of conditions. Finally, we discuss distributions of filament lengths under various conditions and speculate on their potential implication for the emergence of filopodia from the lamellipodial network.

  8. How does the antagonism between capping and anti-capping proteins affect actin network dynamics?

    Science.gov (United States)

    Hu, Longhua; Papoian, Garegin A.

    2011-09-01

    Actin-based cell motility is essential to many biological processes. We built a simplified, three-dimensional computational model and subsequently performed stochastic simulations to study the growth dynamics of lamellipodia-like branched networks. In this work, we shed light on the antagonism between capping and anti-capping proteins in regulating actin dynamics in the filamentous network. We discuss detailed mechanisms by which capping and anti-capping proteins affect the protrusion speed of the actin network and the rate of nucleation of filaments. We computed a phase diagram showing the regimes of motility enhancement and inhibition by these proteins. Our work shows that the effects of capping and anti-capping proteins are mainly transmitted by modulation of the filamentous network density and local availability of monomeric actin. We discovered that the combination of the capping/anti-capping regulatory network with nucleation-promoting proteins introduces robustness and redundancy in cell motility machinery, allowing the cell to easily achieve maximal protrusion speeds under a broader set of conditions. Finally, we discuss distributions of filament lengths under various conditions and speculate on their potential implication for the emergence of filopodia from the lamellipodial network.

  9. How does the antagonism between capping and anti-capping proteins affect actin network dynamics?

    Energy Technology Data Exchange (ETDEWEB)

    Hu Longhua; Papoian, Garegin A, E-mail: gpapoian@umd.edu [Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742 (United States)

    2011-09-21

    Actin-based cell motility is essential to many biological processes. We built a simplified, three-dimensional computational model and subsequently performed stochastic simulations to study the growth dynamics of lamellipodia-like branched networks. In this work, we shed light on the antagonism between capping and anti-capping proteins in regulating actin dynamics in the filamentous network. We discuss detailed mechanisms by which capping and anti-capping proteins affect the protrusion speed of the actin network and the rate of nucleation of filaments. We computed a phase diagram showing the regimes of motility enhancement and inhibition by these proteins. Our work shows that the effects of capping and anti-capping proteins are mainly transmitted by modulation of the filamentous network density and local availability of monomeric actin. We discovered that the combination of the capping/anti-capping regulatory network with nucleation-promoting proteins introduces robustness and redundancy in cell motility machinery, allowing the cell to easily achieve maximal protrusion speeds under a broader set of conditions. Finally, we discuss distributions of filament lengths under various conditions and speculate on their potential implication for the emergence of filopodia from the lamellipodial network.

  10. A novel alpha probe for NORMs at workplaces

    International Nuclear Information System (INIS)

    Radiation protection ordinances now also cover work activities with naturally occurring radioactive materials (NORMs). These materials always contain alpha emitters from the uranium or thorium decay series or from both. Alpha counting is the most sensitive method for screening and requires no shielding and only minute amounts of material, such as dust, sand or wipe tests. Previous gross or spectrometric alpha counters - designed for artificial radionuclides from the nuclear fuel cycle - are unsatisfactory for NORMs at work places. The new requirements are fulfilled by our novel Alpha Probe: a 3'' (44 cm2) ZnS scintillator, a light-tight alpha-transparent foil, a light guide to a 2'' photomultiplier and electronics, all in a handy unit, connected to a Smart Display or to the well established Low Level Monitor LLM 500. The Alpha Probe has been used on numerous environmental samples, industrial raw materials, products and wastes. The limit of detection is 0.2 Bq in 1 min and 1 mBq/cm2 in 10 min gate time. (orig.)

  11. Analysis on the positioning precision of CAPS

    Institute of Scientific and Technical Information of China (English)

    JI YuanFa; SUN XiYan

    2009-01-01

    As a newly developed satellite positioning system,the Chinese Area Positioning System (CAPS) Is a typical direct sequence spread spectrum ranging system like GPS.The positioning precision of such navigation signals depends on many factors,including the pseudo-code rate,the signal to noise ratio,the processing methods for tracking loops and so on.This paper describes the CAPS link budget,the solution approach for CAPS positioning,focusing on the autocorrelation function feature of C/A code signals.The CAPS signal measurement precision is studied by the software approach together with theoretical analysis of the range resolution.Because the conventional Delay Lock Loop (DLL) is vulnerable to the impact of noise,a narrow correlator and multiple correlatore as well as the corresponding discrimination methods of phases are proposed,which improves the robustness of DLL and the code-phase resolution of the measurement.The results show that the Improvement of the DLL structure and the discrimination method are the most important way to improve the ranging resolution.Theoretical analysis and experimental results show that a CAPS receiver could reach a 20-m positioning precision by using three satellites with a supported height from an altimeter.

  12. Analysis on the positioning precision of CAPS

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    As a newly developed satellite positioning system, the Chinese Area Positioning System (CAPS) is a typical direct sequence spread spectrum ranging system like GPS. The positioning precision of such navigation signals depends on many factors, including the pseudo-code rate, the signal to noise ratio, the processing methods for tracking loops and so on. This paper describes the CAPS link budget, the solution approach for CAPS positioning, focusing on the autocorrelation function feature of C/A code signals. The CAPS signal measurement precision is studied by the software approach together with theoretical analysis of the range resolution. Because the conventional Delay Lock Loop (DLL) is vul- nerable to the impact of noise, a narrow correlator and multiple correlators as well as the corresponding discrimination methods of phases are proposed, which improves the robustness of DLL and the code-phase resolution of the measurement. The results show that the improvement of the DLL structure and the discrimination method are the most important way to improve the ranging resolution. Theoretical analysis and experimental results show that a CAPS receiver could reach a 20-m positioning precision by using three satellites with a supported height from an altimeter.

  13. Martian north polar cap summer water cycle

    CERN Document Server

    Brown, Adrian J; Becerra, Patricio; Byrne, Shane

    2016-01-01

    A key outstanding question in Martian science is 'are the polar caps gaining or losing mass and what are the implications for past, current and future climate?' To address this question, we use observations from the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) of the north polar cap during late summer for multiple Martian years, to monitor the summertime water cycle in order to place quantitative limits on the amount of water ice deposited and sublimed in late summer. We establish here for the first time the summer cycle of water ice absorption band signatures on the north polar cap. We show that in a key region in the interior of the north polar cap, the absorption band depths grow until Ls=120, when they begin to shrink, until they are obscured at the end of summer by the north polar hood. This behavior is transferable over the entire north polar cap, where in late summer regions 'flip' from being net sublimating into net condensation mode. This transition or 'mode flip' happens earlier for ...

  14. Carbon nanotube cathode with capping carbon nanosheet

    Science.gov (United States)

    Li, Xin; Zhao, Dengchao; Pang, Kaige; Pang, Junchao; Liu, Weihua; Liu, Hongzhong; Wang, Xiaoli

    2013-10-01

    Here, we report a vertically aligned carbon nanotube (VACNT) film capped with a few layer of carbon nanosheet (FLCN) synthesized by chemical vapor deposition using a carbon source from iron phthalocyanine pyrolysis. The square resistance of the VACNT film is significantly reduced from 1500 Ω/□ to 300 Ω/□ when it is capped with carbon nanosheet. The VACNT capped with carbon nanosheet was transferred to an ITO glass substrate in an inverted configuration so that the carbon nanosheet served as a flexible transparent electrode at the bottom and the VACNT roots served as emission tips. Because all of the VACNTs start growing from a flat silicon substrate, the VACNT roots are very neat and uniform in height. A field emission test of the carbon nanosheet-capped VACNT film proved that the CNT roots show better uniformity in field emission and the carbon nanosheet cap could also potentially serve as a flexible transparent electrode, which is highly desired in photo-assisted field emission.

  15. Review of alpha_s determinations

    OpenAIRE

    Pich, Antonio

    2013-01-01

    The present knowledge on the strong coupling is briefly summarized. The most precise determinations of alpha_s, at different energies, are reviewed and compared at the Z mass scale, using the predicted QCD running. The impressive agreement achieved between experimental measurements and theoretical predictions constitutes a beautiful and very significant test of Asymptotic Freedom, establishing QCD as the fundamental theory of the strong interaction. The world average value of the strong coupl...

  16. World Summary of $\\alpha_s$ (2015)

    CERN Document Server

    Bethke, Siegfried; Salam, Gavin P

    2015-01-01

    This is a preliminary update of the measurements of α s and the determination of the world average value of α s (M Z 2 ) presented in the 2013/2014 edition of the Review of Particle Properties [1]. A number of studies which became available since late 2013 provide new results for each of the (previously 5, now) 6 subclasses of measurements for which pre-average values of $\\alpha_s (M_Z^2)$ are determined.

  17. Quantitative Single-Particle Digital Autoradiography with α-Particle Emitters for Targeted Radionuclide Therapy using the iQID Camera

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Brian W.; Frost, Sophia; Frayo, Shani; Kenoyer, Aimee L.; Santos, E. B.; Jones, Jon C.; Green, Damian J.; Hamlin, Donald K.; Wilbur, D. Scott; Fisher, Darrell R.; Orozco, Johnnie J.; Press, Oliver W.; Pagel, John M.; Sandmaier, B. M.

    2015-07-01

    Abstract Alpha emitting radionuclides exhibit a potential advantage for cancer treatments because they release large amounts of ionizing energy over a few cell diameters (50–80 μm) causing localized, irreparable double-strand DNA breaks that lead to cell death. Radioimmunotherapy (RIT) approaches using monoclonal antibodies labeled with alpha emitters may inactivate targeted cells with minimal radiation damage to surrounding tissues. For accurate dosimetry in alpha-RIT, tools are needed to visualize and quantify the radioactivity distribution and absorbed dose to targeted and non-targeted cells, especially for organs and tumors with heterogeneous radionuclide distributions. The aim of this study was to evaluate and characterize a novel single-particle digital autoradiography imager, iQID (ionizing-radiation Quantum Imaging Detector), for use in alpha-RIT experiments. Methods: The iQID camera is a scintillator-based radiation detection technology that images and identifies charged-particle and gamma-ray/X-ray emissions spatially and temporally on an event-by-event basis. It employs recent advances in CCD/CMOS cameras and computing hardware for real-time imaging and activity quantification of tissue sections, approaching cellular resolutions. In this work, we evaluated this system’s characteristics for alpha particle imaging including measurements of spatial resolution and background count rates at various detector configurations and quantification of activity distributions. The technique was assessed for quantitative imaging of astatine-211 (211At) activity distributions in cryosections of murine and canine tissue samples. Results: The highest spatial resolution was measured at ~20 μm full width at half maximum (FWHM) and the alpha particle background was measured at a rate of (2.6 ± 0.5) × 10–4 cpm/cm2 (40 mm diameter detector area). Simultaneous imaging of multiple tissue sections was performed using a large-area iQID configuration (ø 11.5 cm

  18. Capping complex formation at the slow-growing end of the actin filament.

    Science.gov (United States)

    Kostyukova, A S

    2008-12-01

    Actin filaments are polar; their barbed (fast-growing) and pointed (slow-growing) ends differ in structure and dynamic properties. The slow-growing end is regulated by tropomodulins, a family of capping proteins that require tropomyosins for optimal function. There are four tropomodulin isoforms; their distributions vary depending on tissue type and change during development. The C-terminal half of tropomodulin contains one compact domain represented by alternating alpha-helices and beta-structures. The tropomyosin-independent actin-capping site is located at the C-terminus. The N-terminal half has no regular structure; however, it contains a tropomyosin-dependent actin-capping site and two tropomyosin-binding sites. One tropomodulin molecule can bind two tropomyosin molecules. Effectiveness of tropomodulin binding to tropomyosin depends on the tropomyosin isoform. Regulation of tropomodulin binding at the pointed end as well as capping effectiveness in the presence of specific tropomyosins may affect formation of local cytoskeleton and dynamics of actin filaments in cells. PMID:19216712

  19. Tuning the Magnetic Transport of an Induction LINAC using Emittance

    Energy Technology Data Exchange (ETDEWEB)

    Houck, T L; Brown, C G; Ong, M M; Paul, A C; Wargo, P E; Zentler, J M

    2006-08-11

    The Lawrence Livermore National Laboratory Flash X-Ray (FXR) machine is a linear induction accelerator used to produce a nominal 18 MeV, 3 kA, 65 ns pulse width electron beam for hydrodynamic radiographs. A common figure of merit for this type of radiographic machine is the x-ray dose divided by the spot area on the bremsstrahlung converter where a higher FOM is desired. Several characteristics of the beam affect the minimum attainable x-ray spot size. The most significant are emittance (chaotic transverse energy), chromatic aberration (energy variation), and beam motion (transverse instabilities and corkscrew motion). FXR is in the midst of a multi-year optimization project to reduce the spot size. This paper describes the effort to reduce beam emittance by adjusting the fields of the transport solenoids and position of the cathode. If the magnetic transport is not correct, the beam will be mismatched and undergo envelope oscillations increasing the emittance. We measure the divergence and radius of the beam in a drift section after the accelerator by imaging the optical transition radiation (OTR) and beam envelope on a foil. These measurements are used to determine an emittance. Relative changes in the emittance can be quickly estimated from the foil measurements allowing for an efficient, real-time study. Once an optimized transport field is determined, the final focus can be adjusted and the new x-ray spot measured. A description of the diagnostics and analysis is presented.

  20. The first simplest indicator based on LMMT field emitter

    International Nuclear Information System (INIS)

    Full text: Liquid metal multiple tip (LMMT) electron emitter was created by pulling liquid metal (indium gallium eutectic) through holes in a nuclear membrane of polyethylene terephtalate. The track membranes presently employed in selective clean-up filters are obtained by bombarding a film with heavy ions having energy of several tens of megaelectron volts. After irradiation, the film is illuminated by ultraviolet light and subjected to chemical etching. These membranes are produced by cyclotron of Physico-technical Institute. Liquid metal multiple tip field emitters have some advantages in comparison with solid-state field emitters and explosive electron emitters: unlimited life expectancy, large current densities (>100 mA per sq. cm), practically unlimited surface, stable emission in poor vacuum (10-4 Torr). In this work we report about use of LMMT field emitter on the base of polyethylene terephtalate film with 3 μm-diameter holes as the simplest light indicator. The design of the indicator consists of flat accelerating grid and phosphor glass as collecting electrode. The work stability, surface distribution, longlife are discussed in paper. Refs. 2 (author)

  1. Study of Abnormal Vertical Emittance Growth in ATF Extraction Line

    Energy Technology Data Exchange (ETDEWEB)

    Alabau, M.; Faus-Golfe, A.; /Valencia U., IFIC; Alabau, M.; Bambade, P.; Brossard, J.; Le Meur, G.; Rimbault, C.; Touze, F.; /Orsay, LAL; Angal-Kalinin, D.; Jones, J.K.; /Daresbury; Appleby, R.; Scarfe, A.; /Manchester U.; Kuroda, S.; /KEK, Tsukuba; White, G.R.; Woodley, M.; /SLAC; Zimmermann, F.; /CERN

    2011-11-04

    Since several years, the vertical beam emittance measured in the Extraction Line (EXT) of the Accelerator Test Facility (ATF) at KEK, that will transport the electron beam from the ATF Damping Ring (DR) to the future ATF2 Final Focus beam line, is significantly larger than the emittance measured in the DR itself, and there are indications that it grows rapidly with increasing beam intensity. This longstanding problem has motivated studies of possible sources of this anomalous emittance growth. One possible contribution is non-linear magnetic fields in the extraction region experimented by the beam while passing off-axis through magnets of the DR during the extraction process. In this paper, simulations of the emittance growth are presented and compared to observations. These simulations include the effects of predicted non-linear field errors in the shared DR magnets and orbit displacements from the reference orbit in the extraction region. Results of recent measurements using closed orbit bumps to probe the relation between the extraction trajectory and the anomalous emittance growth are also presented.

  2. Tuning the Magnetic Transport of an Induction LINAC using Emittance

    International Nuclear Information System (INIS)

    The Lawrence Livermore National Laboratory Flash X-Ray (FXR) machine is a linear induction accelerator used to produce a nominal 18 MeV, 3 kA, 65 ns pulse width electron beam for hydrodynamic radiographs. A common figure of merit for this type of radiographic machine is the x-ray dose divided by the spot area on the bremsstrahlung converter where a higher FOM is desired. Several characteristics of the beam affect the minimum attainable x-ray spot size. The most significant are emittance (chaotic transverse energy), chromatic aberration (energy variation), and beam motion (transverse instabilities and corkscrew motion). FXR is in the midst of a multi-year optimization project to reduce the spot size. This paper describes the effort to reduce beam emittance by adjusting the fields of the transport solenoids and position of the cathode. If the magnetic transport is not correct, the beam will be mismatched and undergo envelope oscillations increasing the emittance. We measure the divergence and radius of the beam in a drift section after the accelerator by imaging the optical transition radiation (OTR) and beam envelope on a foil. These measurements are used to determine an emittance. Relative changes in the emittance can be quickly estimated from the foil measurements allowing for an efficient, real-time study. Once an optimized transport field is determined, the final focus can be adjusted and the new x-ray spot measured. A description of the diagnostics and analysis is presented

  3. The Deepest Spectrum in the Universe? Line Emission from Lyman-alpha Clouds at z 3

    Science.gov (United States)

    Bunker, Andrew J.; Rauch, M.; Haehnelt, M.; Becker, G.; Marleau, F.; Graham, J.; Research, European; Inter-Galactic Medium, Training Network on the

    2007-12-01

    We present the results of an extremely deep long-slit optical spectroscopic search for low-luminosity Lyman-alpha emitters. Over several years we have accumulated 150-hours integration on a single field with 8-10m telescopes (VLT/FORS2, Gemini/GMOS and Keck/LRIS) at a spectral resolution of 300km/s. This is the deepest spectrum ever obtained - our 1 sigma sensitivity to line emission in a 1 arcsec2 aperture is 1019erg/cm2/s. We have significant detections of 30 emission line objects, which are most likely Lyman-alpha emitters at 2.7emitters are significantly spatially extended (with median size 4arcsec, 30kpc) and could plausibly be the host population of the high column density Lyman-alpha absorption clouds seen in QSO spectra (the Damped Lyman-alpha Systems and the Lyman-Limit Systems).

  4. Seismic explosion sources on an ice cap

    DEFF Research Database (Denmark)

    Shulgin, Alexey; Thybo, Hans

    2015-01-01

    Controlled source seismic investigation of crustal structure below ice covers is an emerging technique. We have recently conducted an explosive refraction/wide-angle reflection seismic experiment on the ice cap in east-central Greenland. The data-quality is high for all shot points and a full...... crustal model can be modelled. A crucial challenge for applying the technique is to control the sources. Here, we present data that describe the efficiency of explosive sources in the ice cover. Analysis of the data shows, that the ice cap traps a significant amount of energy, which is observed as a...

  5. Design and implementation of the CAPS receiver

    Institute of Scientific and Technical Information of China (English)

    HU YongHui; HUA Yu; HOU Lei; WEI JingFa; WU JianFeng

    2009-01-01

    In this paper,baaed on analyses of the Chinese Area Positioning System (CAPS) satellite (GEO satellite) resources and signal properties,the signal power at the port of the receiver antenna is estimated,and the implementation projects are presented for a switching band C to band L CAPS C/A code receiver integrated with GPS receiver suite and for a CAPS dual frequency P code receiver.A microstrip receiving antenna is designed with high sensitivity and wide beam orientation,the RF front end of the C/A code and P code receivers,and a processor is designed for the navigation baseband.A single frequency CAPS C/A code receiver and a CAPS dual frequency P code receiver are built at the same time.A software process flow is provided,and research on relatively key techniques is also conducted,such as signal searching,code loop and carrier loop algorithms,a height assistant algorithm,a dual frequency difference speed measurement technique,a speed measurement technique using a single frequency source with frequency assistance,and a CAPS time correcting algorithm,according to the design frame of the receiver hardware.Research results show that the static plane positioning accuracy of the CAPS C/A code receiver is 20.5-24.6 m,height accuracy is 1.2-12.8 m,speed measurement accuracy is 0.13-0.3 m/s,dynamic plane positioning accuracy is 24.4 m,height accuracy is 3.0 m,and speed measurement accuracy is 0.24 m/s.In the case of C/A code,the timing accuracy is 200 ha,and it is also shown that the positioning accuracy of the CAPS precise code receiver (1σ) is 5 m from south to north,and 0.8 m from east to west.Finally,research on positioning accuracy is also conducted.

  6. Assembling the CMS yoke end-caps

    CERN Multimedia

    Laurent Guiraud

    2001-01-01

    A crane is used to piece together one of the end-caps that will provide the path for magnetic flux return on the CMS experiment. A total of six end-cap discs will be assembled before being positioned on the barrel yoke to complete the huge 12 500 tonne cylinder yoke. The magnetic field produced will be greater than any other solenoid created to date at 4 T, 100 000 times greater than the Earth's natural magnetic field, and will store enough energy to melt 18 tonnes of gold.

  7. Alpha Emitting Radionuclides and Radiopharmaceuticals for Therapy

    International Nuclear Information System (INIS)

    Today, cancer treatments mainly rely on surgery or external beam radiation to remove or destroy bulky tumors. Chemotherapy is given when tumours cannot be removed or when dissemination is suspected. However, these approaches cannot permanently treat all cancers and relapse occurs in up to 50% of the patients’ population. Radioimmunotherapy (RIT) and peptide receptor radionuclide therapy (PRRT) are effective against some disseminated and metastatic diseases, although they are rarely curative. Most preclinical and clinical developments in this field have involved electron-emitting radionuclides, particularly iodine-131, yttrium-90 and lutetium-177. The large range of the electrons emitted by these radionuclides reduces their efficacy against very small tumour cell clusters or isolated tumour cells present in residual disease and in many haematological tumours (leukaemia, myeloma). The range of alpha particles in biological tissues is very short, less than 0.1 mm, which makes alpha emitters theoretically ideal for treatment of such isolated tumour cells or micro-clusters of malignant cells. Thus, over the last decade, a growing interest for the use of alpha-emitting radionuclides has emerged. Research on targeted alpha therapy (TAT) began years ago in Nantes through cooperation between Subatech, a nuclear physics laboratory, CRCNA, a cancer research centre with a nuclear oncology team and ITU (Karlsruhe, Germany). CD138 was demonstrated as a potential target antigen for Multiple Myeloma, which is a target of huge clinical interest particularly suited for TAT because of the disseminated nature of the disease consisting primarily of isolated cells and small clusters of tumour cells mainly localized in the bone marrow. Thus anti-CD138 antibodies were labelled with bismuth-213 from actinium-225/bismuth-213 generators provided by ITU and used to target multiple myeloma cells. In vitro studies showed cell cycle arrest, synergism with chemotherapy and very little induction

  8. Deep rest-frame far-UV spectroscopy of the giant Lyman α emitter 'Himiko'

    DEFF Research Database (Denmark)

    Zabl, J.; Nørgaard-Nielsen, Hans Ulrik; Fynbo, J. P. U.; Laursen, P.; Ouchi, M.; Kjaergaard, P.

    2015-01-01

    We present deep 10 h VLT/XSHOOTER spectroscopy for an extraordinarily luminous and extended Ly alpha emitter at z = 6.595 referred to asHimiko and first discussed by Ouchi et al., with the purpose of constraining the mechanisms powering its strong emission. Complementary to the spectrum, we discuss...... km s-1 w.r.t. to the peak Ly α redshift. These limits provide strong evidence that an AGN is not a major contribution to Himiko's Ly α flux. Strong conclusions about the presence of Pop III star formation or gravitational cooling radiation are not possible based on the obtained He II upper limit. Our...... Ly alpha spectrum confirms both spatial extent and flux (8.8 +/- 0.5 x 10-17 erg s -1 cm-2) of previous measurements. In addition, we can unambiguously exclude any remaining chance of it being a lower redshift interloper by significantly detecting a continuum redwards of Ly α, while being undetected...

  9. An extreme [OIII] emitter at $z=3.2$: a low metallicity Lyman continuum source

    CERN Document Server

    de Barros, S; Amorín, R; Castellano, M; Siana, B; Grazian, A; Suh, H; Balestra, I; Vignali, C; Verhamme, A; Zamorani, G; Mignoli, M; Hasinger, G; Comastri, A; Pentericci, L; Pérez-Montero, E; Fontana, A; Giavalisco, M; Gilli, R

    2016-01-01

    [Abridged] We investigate the physical properties of a Lyman continuum emitter candidate at $z=3.212$ with photometric coverage from $U$ to MIPS 24$\\mu$m band and VIMOS/VLT and MOSFIRE/Keck spectroscopy. Investigation of the UV spectrum confirms a direct spectroscopic detection of the Lyman continuum emission with $S/N>5$. Non-zero Ly$\\alpha$ flux at the systemic redshift and high Lyman-$\\alpha$ escape fraction suggest a low HI column density. The weak C and Si low-ionization absorption lines are also consistent with a low covering fraction along the line of sight. The [OIII]$\\lambda\\lambda4959,5007+\\mathrm{H}\\beta$ equivalent width is one of the largest reported for a galaxy at $z>3$ ($\\mathrm{EW}([\\mathrm{OIII}]\\lambda\\lambda4959,5007+\\mathrm{H}\\beta) \\simeq 1600\\AA$, rest-frame) and the NIR spectrum shows that this is mainly due to an extremely strong [OIII] emission. The large observed [OIII]/[OII] ratio ($>10$) and high ionization parameter are consistent with prediction from photoionization models in ca...

  10. Studies of cervical caps: I. Vaginal lesions associated with use of the Vimule cap.

    Science.gov (United States)

    Bernstein, G S; Kilzer, L H; Coulson, A H; Nakamura, R M; Smith, G C; Bernstein, R; Frezieres, R; Clark, V A; Coan, C

    1982-11-01

    Prior to investigating the contraceptive efficacy of cervical caps, we undertook a preliminary study to evaluate potential side effects of these devices. Women who had not previously used a cap were randomly assigned to wear either a Vimule or Cavity Rim Cap (CRC) for as long as seven days. The Vimule cap caused lesions of the portio vaginalis ranging from erythematous impressions to abrasions and frank lacerations. There was variation in the degree of trauma depending, in part, on the size of the cap and duration of wear. Disruption of the epithelium occurred in eight of twelve Vimule users, but the lesions were sometimes difficult to see owing to their location. CRCs were worn by 20 women. This device sometimes left a "suction ring" on the cervix but did not disrupt the epithelium. Two of three long-term users of the Vimule cap who were also studied had unusual formations of the vaginal mucosa suggesting a proliferative reaction to chronic irritation. It is recommended that all women using a Vimule Cap be carefully re-examined and counseled about further use of the device according to the findings of the examination. PMID:7160179

  11. Lyman Alpha Control

    CERN Document Server

    Nielsen, Daniel Stefaniak

    2015-01-01

    This document gives an overview of how to operate the Lyman Alpha Control application written in LabVIEW along with things to watch out for. Overview of the LabVIEW code itself as well as the physical wiring of and connections from/to the NI PCI-6229 DAQ box is also included. The Lyman Alpha Control application is the interface between the ALPHA sequencer and the HighFinesse Wavelength Meter as well as the Lyman Alpha laser setup. The application measures the wavelength of the output light from the Lyman Alpha cavity through the Wavelength Meter. The application can use the Wavelength Meter’s PID capabilities to stabilize the Lyman Alpha laser output as well as switch between up to three frequencies.

  12. New ALPHA-2 magnet

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    On 21 June, members of the ALPHA collaboration celebrated the handover of the first solenoid designed for the ALPHA-2 experiment. The magnet has since been successfully installed and is working well.   Khalid Mansoor, Sumera Yamin and Jeffrey Hangst in front of the new ALPHA-2 solenoid. “This was the first of three identical solenoids that will be installed between now and September, as the rest of the ALPHA-2 device is installed and commissioned,” explains ALPHA spokesperson Jeffrey Hangst. “These magnets are designed to allow us to transfer particles - antiprotons, electrons and positrons - between various parts of the new ALPHA-2 device by controlling the transverse size of the particle bunch that is being transferred.” Sumera Yamin and Khalid Mansoor, two Pakistani scientists from the National Centre for Physics in Islamabad, came to CERN in February specifically to design and manufacture these magnets. “We had the chance to work on act...

  13. Hole emitter whispering galleries of photonic quantum ring

    CERN Document Server

    Kwon, O; an, S J; Kim, D K; Lee, S E; Bae, J; Yoon, J H; Park, B H; Kim, J; Ahn, J; Park, S; Kwon, Odae

    2005-01-01

    We report on the first observation of hole whispering gallery lasers from semiconductor microcavities with three dimensional optical confinement, with thresholds potentially reducible to micro-to-nano ampere regimes according to a quadratic size-dependent reduction, due to ideal quantum wire properties of the naturally formed photonic quantum rings before imminent recombination in a dynamic steady state fashion. If the device size grows over a critical diameter, the quantum ring whispering gallery then begins to disappear. However, cooperative small hole arrays like 256x256 quantum ring emitters avoid the criticality and open a possibility of constructing practical dense electro-pumped micro-to-nano watt emitter arrays, amenable to mega-to-giga ring emitter chip development via present fabrication techniques.

  14. Emittance growth in the DARHT Axis-II Downstream Transport

    Energy Technology Data Exchange (ETDEWEB)

    Ekdahl, Jr., Carl August [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Schulze, Martin E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-04-14

    Using a particle-in-cell (PIC) code, we investigated the possibilities for emittance growth through the quadrupole magnets of the system used to transport the high-current electron beam from an induction accelerator to the bremsstrahlung converter target used for flash radiography. We found that even highly mismatched beams exhibited little emittance growth (< 6%), which we attribute to softening of their initial hard edge current distributions. We also used this PIC code to evaluate the accuracy of emittance measurements using a solenoid focal scan following the quadrupole magnets. If the beam is round after the solenoids, the simulations indicate that the measurement is highly accurate, but it is substantially inaccurate for elliptical beams

  15. DC-SC Photoinjector with Low Emittance at Peking University

    CERN Document Server

    Xiang Rong; Hao, J; Huang, Senlin; Lu Xiang Yang; Quan, Shengwen; Zhang, Baocheng; Zhao, Kui

    2005-01-01

    High average power Free Electron Lasers require the high quality electron beams with the low emittance and the sub-picosecond bunches. The design of DC-SC photoinjector, directly combining a DC photoinjector with an SRF cavity, can produce high average current beam with moderate bunch charge and high duty factor. Because of the DC gun, the emittance increases quickly at the beginning, so a carefully design is needed to control that. In this paper, the simulation of an upgraded design has been done to lower the normalized emittance below 1.5mm·mrad. The photoinjector consists of a DC gap and a 2+1/2-cell SRF cavity, and it is designed to produce 4.2 MeV electron beams at 100pC bunch charge and 81.25MHz repetition rate (8 mA average current).

  16. Dosimetry of internal emitters: past, present and future

    International Nuclear Information System (INIS)

    Dosimetry of internal emitters is entirely a post-war development. From the first definitive paper on the subject which appeared in 1948 to the present day MIRD schema, there has been a continued advance in the knowledge of radionuclide decay data, radiation interaction cross-sections, computational methods for obtaining absorbed fractions, mathematical description of anthropometric models, collection and analysis of biokinetic data of internal emitters. After listing out the developments in radiation dose units, the present review briefly summarises the physical and biological bases of the estimation of the mean organ radiation dose, specifically mentioning the contributions from the Institute of Nuclear Medicine and Allied Sciences. The shortcomings of the conventional 'mean organ dose' concept have been brought out, highlighting recent developments in local dosimetry and microdosimetry. The expected potential future developments in dosimetry of internal emitters are also enumerated. (author). 40 refs

  17. Creation of multiple identical single photon emitters in diamond

    CERN Document Server

    Rogers, Lachlan J; Marseglia, Luca; Müller, Christoph; Naydenov, Boris; Schauffert, Hardy; Kranz, C; Teraji, T; Isoya, Junichi; McGuinness, Liam P; Jelezko, Fedor

    2013-01-01

    Emitters of indistinguishable single photons are crucial for the growing field of quantum technologies. To realize scalability and increase the complexity of quantum optics technologies, multiple independent yet identical single photon emitters are also required. However typical solid-state single photon sources are dissimilar, necessitating the use of electrical feedback or optical cavities to improve spectral overlap between distinct emitters. Here, we present controllable growth of bright silicon-vacancy (SiV-) centres in bulk diamond which intrinsically show almost identical emission (spectral overlap of up to 83%) and near transform-limited excitation linewidths. We measure the photo-physical properties of defects at room and cryogenic temperatures, and demonstrate incorporation into a solid immersion lens (SIL). Our results have impact upon the application of single photon sources for quantum optics and cryptography, and the production of next generation fluorophores for bio-imaging.

  18. Auger Emitter Based Radiotherapy- A Possible New Treatment for Cancer

    DEFF Research Database (Denmark)

    Fredericia, Pil; Groesser, Torsten; Severin, Gregory; Köster, U.; Jensen, Andreas Tue Ingemann; Jensen, Mikael

    2014-01-01

    Cancer is a major cause of mortality worldwide (1). A large fraction of cancer patients undergo external radiotherapy, delivering a lethal dose of radiation to the patient’s tumour(s). The main problem with this approach is the collateral damage caused to healthy, surrounding tissue and the side...... damage produced by Low-LET radiation used in current radiotherapy (2-3) Considerable efforts have been made in the past twenty years to develop Auger emitter-based radiotherapy However, previous studies lack precise measurement of RBE, which is the fundamental factor defining the relationship between...... local radiation dose and biological damage done for the given Auger emitter, thereby brought the development to a halt. We believe we have the techniques to quantify the biological damage done for a given Auger emitter and thereby pushing the development of Auger emitterbased radiotherapy into reality...

  19. Study of narrowband single photon emitters in polycrystalline diamond films

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Russell G.; Shimoni, Olga; Martin, Aiden A.; Aharonovich, Igor, E-mail: igor.aharonovich@uts.edu.au [School of Physics and Advanced Materials, University of Technology, Sydney, P.O. Box 123, Broadway, New South Wales 2007 (Australia)

    2014-11-03

    Quantum information processing and integrated nanophotonics require robust generation of single photon emitters on demand. In this work, we demonstrate that diamond films grown on a silicon substrate by microwave plasma chemical vapor deposition can host bright, narrowband single photon emitters in the visible—near infra-red spectral range. The emitters possess fast lifetime (∼several ns), absolute photostability, and exhibit full polarization at excitation and emission. Pulsed and continuous laser excitations confirm their quantum behaviour at room temperature, while low temperature spectroscopy is performed to investigate inhomogeneous broadening. Our results advance the knowledge of solid state single photon sources and open pathways for their practical implementation in quantum communication and quantum information processing.

  20. Emittance measurements results with upgraded setup at PITZ

    Energy Technology Data Exchange (ETDEWEB)

    Vashchenko, Grygorii; Asova, Galina; Gross, Matthias; Hakobyan, Levon; Isaev, Igor; Ivanisenko, Yevgeniy; Khojoyan, Martin; Klemz, Guido; Krasilnikov, Mikhail; Mahgoub, Mahmoud; Malyutin, Dmitriy; Otevrel, Marek; Petrosyan, Bagrat; Riechter, Dieter; Rimjaem, Sakhorn; Shapovalov, Andrey; Stephan, Frank [DESY, Zeuthen (Germany); Nozdrin, Mikhail [JINR, Dubna (Russian Federation); Templin, Horst-Ingo; Will, Ingo [MBI, Berlin (Germany)

    2012-07-01

    The photo injector test facility at DESY, Zeuthen site, PITZ develops and characterizes photoelectron sources for linac driven free electron lasers (FELs) such as FLASH and the European XFEL. The main goal of the PITZ is to obtain electron beams with low transverse normalize emittance which is necessary for the successful operation of SASE FEL. Major parts of the facility - gun and booster cavities, photocathode laser system were upgraded in 2010 in order to improve the photo injector performance. A slit technique is used at PITZ to reconstruct the transverse phase space of the electron beam. Many machine parameters were tuned to optimize the beam emittance for a wide range of the bunch charge - from 20 pC to 2 nC. Measured emittance depending on various machine parameters like a gun launching phase, booster gradient, laser spot size on the cathode and main solenoid current is presented.