WorldWideScience

Sample records for cap alpha emission

  1. MFTF-. cap alpha. + T progress report

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, W.D. (ed.)

    1985-04-01

    Early in FY 1983, several upgrades of the Mirror Fusion Test Facility (MFTF-B) at Lawrence Livermore National Laboratory (LLNL) were proposed to the fusion community. The one most favorably received was designated MFTF-..cap alpha..+T. The engineering design of this device, guided by LLNL, has been a principal activity of the Fusion Engineering Design Center during FY 1983. This interim progress report represents a snapshot of the device design, which was begun in FY 1983 and will continue for several years. The report is organized as a complete design description. Because it is an interim report, some parts are incomplete; they will be supplied as the design study proceeds. As described in this report, MFTF-..cap alpha..+T uses existing facilities, many MFTF-B components, and a number of innovations to improve on the physics parameters of MFTF-B. It burns deuterium-tritium and has a central-cell Q of 2, a wall loading GAMMA/sub n/ of 2 MW/m/sup 2/ (with a central-cell insert module), and an availability of 10%. The machine is fully shielded, allows hands-on maintenance of components outside the vacuum vessel 24 h after shutdown, and has provisions for repair of all operating components.

  2. Increased 5. cap alpha. -reductase activity in idiopathic hirsutism

    Energy Technology Data Exchange (ETDEWEB)

    Serafini, P.; Lobo, R.A.

    1985-01-01

    In vitro, genital skin 5..cap alpha..-reductase activity (5..cap alpha..-RA) was measured in ten hirsute women with normal androgen levels (idiopathic hirsutism (IH)) and in ten hirsute women with elevated androgen levels (polycystic ovary syndrome (PCO)) in order to determine the influence of secreted androgens on 5..cap alpha..-RA. In vitro 5..cap alpha..-RA was assessed by incubations of skin with /sup 14/C-testosterone (T) for 2 hours, after which steroids were separated and the radioactivity of dihydrotestosterone (DHT) and 5..cap alpha..-androstane 3..cap alpha..-17..beta..-estradiol (3..cap alpha..-diol) in specific eluates were determined. All androgens were normal in IH with the exception of higher levels of 3..cap alpha..-diol glucuronide which were similar to the levels of PCO. The conversion ratio (CR) of T to DHT in IH and PCO were similar, yet significantly greater than the CR of control subjects. The CR of T to 3..cap alpha..-diol in IH and PCO were similar, yet higher than in control subjects. Serum androgens showed no correlation with 5..cap alpha..-RA, while the CR of T to DHT showed a significant positive correlation with the Ferriman and Gallwey score. The increased 5..cap alpha..-RA in IH appears to be independent of serum androgen levels and is, therefore, an inherent abnormality. The term idiopathic is a misnomer, because hirsutism in these patients may be explained on the basis of increased skin 5..cap alpha..-RA.

  3. Trafficking of. cap alpha. -L-fucosidase in lymphoid cells

    Energy Technology Data Exchange (ETDEWEB)

    DiCioccio, R.A.; Brown, K.S.

    1987-05-01

    The quantity of ..cap alpha..-L-fucosidase in human serum is determined by heredity. The mechanism controlling levels of the enzyme in serum is unknown. To investigate this, lymphoid cell lines derived from individuals with either low, intermediate or high ..cap alpha..-L-fucosidase in serum were established. Steady state levels of extracellular ..cap alpha..-L-fucosidase protein and activity overlapped among the cell lines. Thus, in vivo serum phenotypes of ..cap alpha..-L-fucosidase are not adequately expressed in this system. ..cap alpha..-L-Fucosidase was also metabolically labelled with /sup 35/S-methionine, immunoprecipitated, and examined by SDS-PAGE. Cells pulse-labelled from 0.25-2 h had a major intracellular form of enzyme (Mr = 58,000). Cells pulsed for 1.5 h and chased for 21 h with unlabeled methionine had an intracellular form of Mr = 60,000 and an extracellular form of Mr = 62,000. Cells treated with chloroquine had only the 58,000-form both intra- and extra-cellularly. Moreover, chloroquine did not effect the quantitative distribution of ..cap alpha..-L-fucosidase between cells and medium. In fibroblasts, chloroquine enhanced the secretion of newly made lysosomal enzymes and blocked the processing of intercellular enzyme forms from a higher to a lower molecular mass. Thus, there are trafficking differences between ..cap alpha..-L-fucosidase in lymphoid cells and lysosomal enzymes in fibroblasts. This suggests that alternative targeting mechanisms for lysosomal enzymes exist in these cells.

  4. Mechanism of radiation graft of methyl-. cap alpha. -fluoroacrylate and. cap alpha. ,. beta. ,. beta. -trifluorostyrene on perfluorinated copolymer. [Cobalt 60

    Energy Technology Data Exchange (ETDEWEB)

    Ivankin, A.N.; Tevlina, A.S.; Zagorets, P.A. (Moskovskij Khimiko-Tekhnologicheskij Inst. (USSR))

    1983-04-01

    The kinetics of radiation-induced graft copolymerization of methyl-..cap alpha..-fluoroacrylate and ..cap alpha.., ..beta.., ..beta..-trifluorostyrene to perfluorinated copolymer of hexafluoropropylene with tetrafluoroethylene has been studied. The orders of the grafting reaction towards the monomer and dose rate as well as the values of rate constants of radiation-induced grafting at various temperatures were determined, the effective activation energy of grafting (20.6 kJ/mol) was calculated. The kinetic scheme of elementary acts of radiation-induced graft copolymerization is discussed.

  5. Gamma ray pulsars emission from extended polar cap cascades

    CERN Document Server

    Daugherty, J K; Daugherty, Joseph K; Harding, Alice K

    1995-01-01

    We have used a Monte Carlo simulation of a Polar Cap (PC) model of gamma-ray pulsars to estimate light curves and phase-resolved spectra for sources whose rotational and magnetic axes are oriented so that only one of the magnetic poles produces emission directed at the Earth. In this Single Polar Cap (SPC) scenario, even sources whose light curves have two distinct peaks (Crab, Vela, Geminga, PSR B1951+32) are due to emission concentrated near the rim of a single PC. If the inclination alpha is comparable to the half-width of the PC gamma-beam, alpha ~ theta_{b}, the peak-to-peak phase separation can have the large values (0.4 - 0.5) observed from these sources. In the model presented here we attribute the observed interpeak emission to pair cascades above the PC interior. Our simulation assumes the physics of conventional PC models, in which the gamma rays are due to photon-pair cascades initiated by curvature radiation from the acceleration of electrons above the PCs. In this work we assume that the acceler...

  6. Protective effect of. cap alpha. -human atrial natriuretic polypeptide (. cap alpha. -hANP) on chemical-induced pulmonary edema

    Energy Technology Data Exchange (ETDEWEB)

    Imamura, T.; Ohnuma, N.; Iwasa, F.; Furuya, M.; Hayashi, Y.; Inomata, N.; Ishihara, T.; Noguchi, T.

    1988-01-01

    It has been established that ..cap alpha..-hANP, the newly discovered peptide extracted from human cardiac atria, has potent natriuretic and hypotensive actions. The authors present investigation is the first to demonstrate that ..cap alpha..-hANP is capable of protecting against pulmonary edema caused by various chemicals, using isolated perfused guinea pig lung system. Lungs were perfused via pulmonary artery with Krebs-Ringer bicarbonate buffer at 5.0 ml/min, and wet weight of lungs and perfusion pressure of pulmonary artery (Pa) were monitored. Bolus injection of Triton-X or CHAPS into cannulated pulmonary artery produced enema as indicated by a massive increase in wet weight and a slight increase in Pa. Constant infusion of ..cap alpha..-hANP through pulmonary artery at 200 ng/ml was effective in causing decrease in wet weight of lung. Perfusion of lung with paraquat or PGF/sub 2..cap alpha..'/, and repeated bolus injection of arachidonic acid or PGE/sub 2/ caused elevation in both wet weight of lung and Pa.

  7. Complete O(. cap alpha. ) corrections to polarized Compton scattering

    Energy Technology Data Exchange (ETDEWEB)

    Gongora-T, A.; Stuart, R.G.

    1989-04-01

    General expressions for Compton scattering and its O(..cap alpha..) real and virtual corrections are given for electron and photon beams with arbitrary polarization. The expressions obtained are suitable for use in Monte Carlo simulations of Compton polarimeters planned for polarized e/sup +/e/sup -/ colliders. The basis for the calculation are the spinor techniques recently applied to photon and gluon bremsstrahlung. The practical application of these techniques for massive fermions is discussed.

  8. High maltose-producing. cap alpha. -amylase of Penicillium expansum

    Energy Technology Data Exchange (ETDEWEB)

    Doyle, E.M.; Kelly, C.T.; Fogarty, W.M.

    1989-05-01

    An ..cap alpha..-amylase capable of producing exceptionally high levels of maltose (74%) from starch has been identified from a strain of Penicillium expansum. The enzyme is produced extracellularly and was purified to homogeneity by starch adsorption and Sephadex gel filtration chromatography. P. expansum ..cap alpha..-amylase has a pH optimum of 4.5 and is stable in the pH range of 3.6-6.0. Other properties include a temperature optimum of 60/sup 0/C, a molecular weight of 69 000 and and isoelectrtic point of 3.9. The most outstanding feature of the P. expansum enzyme is its ability to yield 14% more maltose and 17.1% less maltotriose than a currently used commercial enzyme. This may be partly explained by the greater affinity of this new enzyme for maltotriose (K/sub m/=0.76 mM) relative to the commercial enzyme, Fungamyl (K/sub m/=2.9 mM). The enzyme reported here is unique among fungal ..cap alpha..-amylases in being able to produce such high levels of maltose and its physicochemical properties suggest that it has potential for commercial development.

  9. Affinity chromatography of alpha/sub 2/-adrenergic receptors (. cap alpha. /sub 2/AR) from pig cerebral cortex

    Energy Technology Data Exchange (ETDEWEB)

    Repaske, M.G.; Limbird, L.E.

    1986-03-01

    A high capacity, ..cap alpha../sub 2/AR-selective affinity resin (YOH. ag) has been prepared by coupling yohimbinic acid to diaminodipropylamine agarose with 1,3 dicyclohexylcarbodiimide. Unreacted amino groups on the agarose matrix are blocked subsequently by acetylation. One volume of YOH. ag adsorbs 75% of the ..cap alpha../sub 2/AR from 50 volumes of digitonin-solubilized preparation containing 0.2 pmol ..cap alpha../sub 2/AR/mg protein. Digitonin-solubilized preparations are derived from cholate extracts of porcine cerebral cortex containing approx. 0.075 pmol ..cap alpha../sub 2/AR/mg protein. Adsorption of ..cap alpha../sub 2/AR to YOH. ag is selective and thus is blocked by the ..cap alpha..-adrenergic antagonist phentolamine. Adsorbed ..cap alpha../sub 2/AR are eluted with 10 ..mu..M phentolamine (20% yield) after removal of non-related proteins with NaCl gradients. Following hydroxylapatite chromatography to concentrate ..cap alpha..''AR and to remove phentolamine, the ..cap alpha..AR is present at 200-400 pmol/mg protein, assayed using sub-saturating concentrations of (/sup 3/H)-yohimbine. (It is estimated that the specific activity of a homogeneous ..cap alpha../sub 2/AR preparation would be 12,000-16,000 pmol/mg protein.) The availability of large quantities of cortical ..cap alpha../sub 2/AR and a resin easily prepared from commercially-supplied reagents suggests that purification of quantities of ..cap alpha../sub 2/AR sufficient for subsequent biochemical studies is feasible.

  10. Radioimmunoassay determination of decreased amounts of. cap alpha. -L-fucosidase protein in fucosidosis

    Energy Technology Data Exchange (ETDEWEB)

    Andrews-Smith, G.L.; Alhadeff, J.A. (California Univ., San Diego, La Jolla (USA). Dept. of Neurosciences)

    1982-03-15

    Purified human liver ..cap alpha..-L-fucosidase (EC 3.2.1.51) has been radioiodinated by a chloramine-T procedure to a specific activity of 3.7 x 10/sup 6/ dpm/..mu..g protein without altering its apparent Michaelis constant for the 4-methylumbelliferyl substrate. This /sup 125/I-labeled ..cap alpha..-L-fucosidase has been used in development of a competitive binding radioimmunoassay for ..cap alpha..-L-fucosidase which can detect 1-2 ng of enzyme protein and has been employed to quantify the amount of ..cap alpha..-L-fucosidase protein in the liver and spleen from a patient with fucosidosis. Less than 1% of the normal amount of ..cap alpha..-L-fucosidase protein is present suggesting that normal amounts of catalytically inactive ..cap alpha..-L-fucosidase are not found in this disease.

  11. Concept of a (1-. cap alpha. ) performance confidence interval

    Energy Technology Data Exchange (ETDEWEB)

    Leong, H.H.; Johnson, G.R.; Bechtel, T.N.

    1980-01-01

    A multi-input, single-output system is assumed to be represented by some model. The distribution functions of the input and the output variables are considered to be at least obtainable through experimental data. Associated with the computer response of the model corresponding to given inputs, a conditional pseudoresponse set is generated. This response can be constructed by means of the model by using the simulated pseudorandom input variates from a neighborhood defined by a preassigned probability allowance. A pair of such pseudoresponse values can then be computed by a procedure corresponding to a (1-..cap alpha..) probability for the conditional pseudoresponse set. The range defined by such a pair is called a (1-..cap alpha..) performance confidence interval with respect to the model. The application of this concept can allow comparison of the merit of two models describing the same system, or it can detect a system change when the current response is out of the performance interval with respect to the previously identified model. 6 figures.

  12. Improved radioimmunoassay for thymosin. cap alpha. 1 recognizes the N-14 amino terminus

    Energy Technology Data Exchange (ETDEWEB)

    Naylor, P.H.; Goldstein, A.L.

    1986-03-01

    Thymosin ..cap alpha../sub 1/(T..cap alpha../sub 1/) is a biologically active thymic peptide currently undergoing trials as an immunomodulator in cancer patients and patients with immunodeficiencies. Abnormally elevated levels of T..cap alpha../sub 1/ have been found in the serum of individuals with or at risk for AIDS, with T-cell leukemias, and chronic progressive multiple sclerosis. Absorption of the current antibody with a synthetic C-14 fragment of T..cap alpha../sub 1/ results in an antisera specific for the N-14 amino terminus of T..cap alpha../sub 1/, which measures significantly higher levels of T..cap alpha../sub 1/ in serum from normal individuals and significantly increases the sensitivity of the assay. Ongoing studies indicate that this new RIA for T..cap alpha../sub 1/ will be useful in monitoring changes of immunoreactive T..cap alpha../sub 1/ in serum with age and in patients with known or suspected T-cell abnormalities.

  13. Purification and characterization of the human platelet. cap alpha. /sub 2/-adrenergic receptor

    Energy Technology Data Exchange (ETDEWEB)

    Shreeve, S.M.; Kerlavage, A.R.; Fraser, C.M.; Mariani, A.P.; Venter, J.C.

    1986-05-01

    The ..cap alpha../sub 2/-receptor (..cap alpha../sub 2/-R) from human platelets has been purified to homogeneity using a four step process. An affinity column was prepared by coupling p-aminoclonidine to CH-Sepharose 4B via the p-NH/sub 2/ group. Digitonin solubilized ..cap alpha../sub 2/-R bound to the affinity matrix were eluted with 100 ..mu..M phentolamine and directly applied to a DEAE-Sepharose column. Bound receptors were eluted with a linear gradient of 0-500 mM NaCl, pooled and chromatographed on HPLC size exclusion columns. Three peaks of ..cap alpha../sub 2/-R binding were eluted from HPLC columns (t = 33, 42, 47 min). Radioiodination of HPLC eluates and analysis by SDS-PAGE indicated that ..cap alpha../sub 2/-R binding was associated with a 75-85 kDa protein. These data suggest that the ..cap alpha../sub 2/-R may exist in monomeric and oligomeric forms in the purified state and support previous target size data which indicate that the ..cap alpha../sub 2/-R exists as a dimer in the native membrane. The pure radioiodinated ..cap alpha../sub 2/-R (77-85 kDa) is a glycoprotein with terminal sialic acid or N-acetylglucosamine residues and has a pI of 4.1 on column isoelectric focusing. These data are consistent with those previously reported on the partially purified ..cap alpha../sub 2/-R. Electron micrographs confirm the oligomeric nature and size of the pure ..cap alpha../sub 2/-R.

  14. Purification and reconstitution of the human platelet. cap alpha. /sub 2/-adrenergic receptor

    Energy Technology Data Exchange (ETDEWEB)

    Regan, J.W.; Cerione, R.A.; Nakata, H.; Benovic, J.L.; DeMarinis, R.M.; Caron, M.G.; Lefkowitz, R.J.

    1986-05-01

    Human platelet ..cap alpha../sub 2/-adrenergic receptors have been purified approx.80,000 fold to apparent homogeneity by a five step chromatographic procedure. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of radioiodinated protein from purified receptor preparations shows a single major band of M/sub r/ 64,000. The competitive binding of ligands to the purified receptor protein shows the proper ..cap alpha../sub 2/-adrenergic specificity. The ..cap alpha../sub 2/-adrenergic receptor contains an essential sulfhydryl residues. Thus, exposure of the purified receptor to the sulfhydryl specific reagent, phenylmercuric chloride (PMC), resulted in a 80% loss of binding activity. This loss of binding activity was prevented when exposure to PMC was done in the presence of ..cap alpha../sub 2/-adrenergic ligands and it was reversed by subsequent exposure to dithiothreitol. Partial proteolysis of purified ..cap alpha../sub 2/-adrenergic receptors was obtained with S. aureus V-8 protease, ..cap alpha..-chymotrypsin and papain. In a comparison with purified ..beta../sub 2/-adrenergic receptors no common partial proteolytic products were found. Partially purified preparations of the ..cap alpha../sub 2/-adrenergic receptor were successfully reconstituted into phospholipid vesicles with the inhibitory guanyl nucleotide-binding regulatory protein, N/sub i/. In these reconstituted preparations, epinephrine could stimulate, and phentolamine could block, the GTPase activity of N/sub i/.

  15. Deletional rearrangement in the human T-cell receptor. cap alpha. -chain locus

    Energy Technology Data Exchange (ETDEWEB)

    de Villartay, J.P.; Lewis, D.; Hockett, R.; Waldmann, T.A.; Korsmeyer, S.J.; Cohen, D.I.

    1987-12-01

    The antigen-specific receptor on the surface of mature T lymphocytes is a heterodimer consisting of polypeptides termed ..cap alpha.. and ..beta... In the course of characterizing human T-cell tumors with an immature (CD4/sup -/, CD8/sup -/) surface phenotype, the authors detected a 2-kilobase ..cap alpha..-related transcript. Analysis of cDNA clones corresponding to this transcript established that a genetic element (which they call TEA, for T early ..cap alpha..) located between the ..cap alpha..-chain variable- and joining-region genes had been spliced to the ..cap alpha.. constant region. The TEA transcript is present early in thymocyte ontogeny, and its expression declines during T-cell maturation. More important, the TEA area functions as an active site for rearrangement within the ..cap alpha.. gene locus. Blot hybridization of restriction enzyme-digested DNA with a TEA probe revealed a narrowly limited pattern of rearrangement in polyclonal thymic DNA, surprisingly different from the pattern expected for the mature ..cap alpha.. gene with its complex diversity. These DNA blots also showed that TEA is generally present in the germ-line configuration in cells expressing the ..gamma..delta heterodimeric receptor and is deleted from mature (..cap alpha beta..-expressing) T-lymphocyte tumors and lines. Moreover, the TEA transcript lacked a long open reading frame for protein but instead possessed multiple copies of a repetitive element resembling those utilized in the heavy-chain class switch of the immunoglobulin genes. The temporal nature of the rearrangements and expression detected by TEA suggests that this recombination could mediate a transition between immature (..gamma..delta-expressing) T cells and mature (..cap alpha beta..-expressing) T cells.

  16. Increased concentration of. cap alpha. - and. gamma. -endorphin in post mortem hypothalamic tissue of schizophrenic patients

    Energy Technology Data Exchange (ETDEWEB)

    Wiegant, V.M.; Verhoef, C.J.; Burbach, J.P.H.; de Wied, D.

    1988-01-01

    The concentrations of ..cap alpha..-, ..beta..- and ..gamma..-endorphin were determined by radioimmunoassay in HPLC fractionated extracts of post mortem hypothalamic tissue obtained from schizophrenic patients and controls. The hypothalamic concentration of ..cap alpha..- and ..gamma..-endorphin was significantly higher in patients than in controls. No difference was found in the concentration of ..beta..-endorphin, the putative precursor of ..cap alpha..- and ..gamma..-endorphins. These results suggest a deviant metabolism of ..beta..-endorphin in the brain of schizophrenic patients. Whether this phenomenon is related to the psychopathology, or is a consequence of ante mortem farmacotherapy, remains to be established.

  17. Crosslinking of. cap alpha. -bungarotoxin to the acetylcholine receptor from Torpedo marmorata by ultraviolet light irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Oswald, R.E. (New York State Veterinary Coll., Ithaca (USA)); Changeux, J.P. (Institut Pasteur, 75 - Paris (France))

    1982-03-22

    The acetylcholine (ACh) receptor purified from the electric organ of Torpedo (sp) is an oligomer composed of 4 different subunits. The ..cap alpha.. subunit is labeled by affinity reagents known to bind to, or in the close vicinity of, the ACh binding site. The ..cap alpha..-toxins from snake venoms behave as competitive antagonists of ACh for its site. The authors have found that ..cap alpha..-/sup 125/I-bungarotoxin (Bgt) can be crosslinked covalently to ACh receptor subunits by simple UV irradiation. This allows the analysis of toxin-receptor crosslinked products without the complication of an intervening 'crosslinking arm'.

  18. Structure of. cap alpha. -phase in two-phase titanium alloys

    Energy Technology Data Exchange (ETDEWEB)

    Gridnev, V.N.; Ivasishin, O.M.; Svechnikov, V.L. (AN Ukrainskoj SSR, Kiev. Inst. Metallofiziki)

    1982-08-01

    The structure of ..cap alpha..-phase in ..beta..-annealed titanium alloys VT 6 and VT 23 and its changes on heating up to ..cap alpha..+..beta.. ..-->.. ..beta.. transformation temperatures with accelerated cooling is studied. An assumption is made that the observed peculiarities of the residual ..cap alpha..-phase structure in alloys after such treatment are the consequence of the relaxation of interphase stresses resulting from a partial polymorphic transformation while the relaxation mechanism is determined by the alloying degree and initial alloy morphology.

  19. Introduction of the human pro. cap alpha. 1(I) collagen gene into pro. cap alpha. 1(I)-deficient Mov-13 mouse cells leads to formation of functional mouse-human hybrid type I collagen

    Energy Technology Data Exchange (ETDEWEB)

    Schnieke, A.; Dziadek, M.; Bateman, J.; Mascara, T.; Harbers, K.; Gelinas, R.; Jaenisch, R.

    1987-02-01

    The Mov-13 mouse strain carries a retroviral insertion in the pro..cap alpha..1(I) collagen gene that prevents transcription of the gene. Cell lines derived from homozygous embryos do not express type I collagen although normal amounts of pro..cap alpha..2 mRNA are synthesized. The authors have introduced genomic clones of either the human or mouse pro..cap alpha..1(I) collagen gene into homozygous cell lines to assess whether the human or mouse pro..cap alpha..1(I) chains can associate with the endogenous mouse pro..cap alpha..2(I) chain to form stable type I collagen. The human gene under control of the simian virus 40 promoter was efficiently transcribed in the transfected cells. Protein analyses revealed that stable heterotrimers consisting of two human ..cap alpha..1 chains and one mouse ..cap alpha..2 chain were formed and that type I collagen was secreted by the transfected cells at normal rates. However, the electrophoretic migration of both ..cap alpha..1(I) and ..cap alpha..2(I) chains in the human-mouse hybrid molecules were retarded, compared to the ..cap alpha..(I) chains in control mouse cells. Inhibition of the posttranslational hydroxylation of lysine and proline resulted in comigration of human and mouse ..cap alpha..1 and ..cap alpha..2 chains, suggesting that increased posttranslational modification caused the altered electrophoretic migration in the human-mouse hybrid molecules. Amino acid sequence differences between the mouse and human ..cap alpha.. chains may interfere with the normal rate of helix formation and increase the degree of posttranslational modifications similar to those observed in patients with lethal perinatal osteogenesis imperfecta. The Mov-13 mouse system should allow the authors to study the effect specific mutations introduced in transfected pro..cap alpha..1(I) genes have on the synthesis, assembly, and function of collagen I.

  20. Synthetic. cap alpha. subunit peptide 125-147 of human nicotinic acetylcholine receptor induces antibodies to native receptor

    Energy Technology Data Exchange (ETDEWEB)

    McCormick, D.J.; Griesmann, G.E.; Huang, Z.; Lennon, V.A.

    1986-03-05

    A synthetic peptide corresponding to residues 125-147 of the Torpedo acetylcholine receptor (AChR) ..cap alpha.. subunit proved to be a major antigenic region of the AChR. Rats inoculated with 50 ..mu..g of peptide (T ..cap alpha.. 125-147) developed T cell immunity and antibodies to native AChR and signs of experimental autoimmune myasthenia gravis. They report the synthesis and preliminary testing of a disulfide-looped peptide comprising residues 125-147 of the human AChR ..cap alpha.. subunit. Peptide H ..cap alpha.. 125-147 differs from T ..cap alpha.. 125-147 at residues 139 (Glu for Gln) and 143 (Ser for Thr). In immunoprecipitation assays, antibodies to Torpedo AChR bound /sup 125/I-labelled H..cap alpha.. 125-147 antibody bound H..cap alpha.. 125-147, but monoclonal antibodies to an immunodominant region of native AChR bound neither H..cap alpha.. 125-147 nor T ..cap alpha.. 125-147. Rats immunized with H ..cap alpha.. 125-147 produced anti-mammalian muscle AChR antibodies that induced modulation of AChRs from cultured human myotubes. Thus, region 125-147 of the human AChR ..cap alpha.. subunit is extracellular in muscle, and is both antigenic and immunogenic. It remains to be determined whether or not autoantibodies to this region may in part cause the weakness or myasthenia gravis in man.

  1. Regulation of the synthesis of barley aleurone. cap alpha. -amylase by gibberellic acid and calcium ions

    Energy Technology Data Exchange (ETDEWEB)

    Jones, R.L.; Carbonell, J.

    1984-09-01

    The effects of gibberellic acid (GA/sub 3/) and calcium ions on the production of ..cap alpha..-amylase and acid phosphatase by isolated aleurone layers of barley (Hordeum vulgare L. cv Himalaya) were studied. Aleurone layers not previously exposed to GA/sub 3/ or CA/sup 2 +/ show qualitative and quantitative changes in hydrolase production following incubation in either GA/sub 3/ or CA/sup 2 +/ or both. In cubation in H/sub 2/O or CA/sup 2 +/ results in the production of low levels of ..cap alpha..-amylase or acid phosphatase. The addition of GA/sub 3/ to the incubation medium causes 10- to 20-fold increase in the amounts of these enzymes released from the tissue, and addition of CA/sup 2 +/ at 10 millimolar causes a further 8- to 9-fold increase in ..cap alpha..-amylase release and a 75% increase in phosphatase release. Production of ..cap alpha..-amylase isoenzymes is also modified by the levels of GA/sub 3/ and CA/sup 2 +/ in the incubation medium. ..cap alpha..-amylase 2 is produced under all conditions of incubation, while ..cap alpha..-amylase 1 appears only when layers are incubated in GA/sub 3/ or GA/sub 3/ plus CA/sup 2 +/. The synthesis of ..cap alpha..-amylases 3 and 4 requires the presence of both GA/sub 3/ and CA/sup 2 +/ in the incubation medium. Laurell rocket immunoelectrophoresis shows that two distinct groups of ..cap alpha..-amylase antigens are present in incubation media of aleurone layers incubated with both GA/sub 3/ and CA/sup 2 +/, while only one group of antigens is found in media of layers incubated in GA/sub 3/ alone. Strontium ions can be substituted for CA/sup 2 +/ in increasing hydrolase production, although higher concentrations of Sr/sup 2 +/ are requried for maximal response. We conclude that GA/sub 3/ is required for the production of ..cap alpha..-amylase 1 and that both GA/sub 3/ and either CA/sup 2 +/ or Sr/sup 2 +/ are required for the production of isoenzymes 3 and 4 of barley aleurone ..cap alpha..-amylase. 22 references, 8

  2. Lyman alpha emission in starburst galaxies

    Science.gov (United States)

    Kunth, Daniel

    1999-07-01

    We propose to perform a deep study of Ly-alpha emission and destruction in 3 star-forming galaxies. These objects have been already observed with the GHRS and exhibit a variety of situations, with Ly-alpha showing P Cyg profiles, secondary emissions or even a deep damped absorption line with no emission. They also span a range of intrinsic properties: IZW18 is a gas-rich, metal deficient dust free dwarf galaxy, Haro 2 has a simple morphology while IRAS 08339+6517 is a luminous IRAS starburst galaxy with more dust and complex Ly- alpha profile. The use of STIS will allow for the first time to study the geometrical/kinematical configuration of the ionized and neutral gas across the galaxies nuclear regions and pin point the effects of porosity and the kinematical structure of the ISM, that may play the key roles {in addition to dust} in the detectability of the line. This study will have important impact for cosmology since Ly-alpha emitters are nowaday found at high-re dshift. We strongly emphasize that since Ly-alpha is primarely a diagnostic of the ISM, a full understanding of how the ISM and Ly-alpha are related is a necessary step before we can hope to correlate Ly-alpha to the cosmic star-formation rate. Our results will be interpreted against the model of superbubble evolution developed with G. Tenorio Tagle.

  3. Genetic recombination within the human T-cell receptor. cap alpha. -chain gene complex

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, M.A.; Kindt, T.J.

    1987-12-01

    Genetic analyses of the human T-cell receptor (TCR) ..cap alpha..-chain genes indicate that recombination events may occur frequently within this gene complex. Examination of the inheritance of restriction fragment length polymorphisms (RFLP) detected by using probes for constant or variable region gene segments made it possible to assign TCR..cap alpha.. haplotypes to the 16 parents and 43 offspring of eight families studied. A total of six RFLP, three for the constant region and three for variable region segments, were examined in the present studies. Most enzyme and probe combinations tested revealed no polymorphism and those finally selected for the study showed limited polymorphism in that only two or, in one case, three allelic forms of the gene were seen. In spite of limited variability at this level, extensive heterogeneity was observed for the combinations of markers present in haplotypes, suggesting that frequent recombination events have occurred. Most strikingly, multiple combinations of RFLP occurring in close proximity of the TCR..cap alpha.. constant region gene were observed in this study. A high recombination frequency for the TCR..cap alpha.. gene complex is further supported by the observation that two children, one in each of two families, inherited recombinant TCR..cap alpha.. haplotypes.

  4. Polar Cap Model for Pulsar High-Energy Emission

    CERN Document Server

    Harding, A K; Harding, Alice K.; Muslimov, Alexander G.

    2002-01-01

    The study of physical processes associated with particle acceleration in the open field line region above the polar cap (PC) of an isolated neutron star (NS) plays a fundamental role in our understanding and interpretation of high-energy emission from pulsars. The systematic study of particle acceleration and formation of electron-positron pair fronts above the PCs of NSs was initiated two decades ago. The detailed analysis of these processes is now possible with the development of pair cascade codes that enables us to calculate the spectra and pulse profiles of high-energy emission from pulsars. The calculation of pair formation and gamma-ray production is being improved to include new results on the PC physics. We briefly outline the current status of the PC model for pulsar high-energy emission, focusing on some of our most recent results on the theoretical modeling of the PC acceleration and gamma-ray emission.

  5. Biological activity of 1. cap alpha. -hydroxyvitamin D/sub 2/ in the rat

    Energy Technology Data Exchange (ETDEWEB)

    Reeve, L.E.; Schnoes, H.K.; DeLuca, H.F.

    1978-01-01

    The biological activity of 1..cap alpha..-hydroxyvitamin D/sub 2/ has been determined in vitamin D-deficient rats. In the calcification of the rachitic epiphyseal plate, 1..cap alpha..-hydroxyvitamin D/sub 2/ is more active than 25-hydroxyvitamin D/sub 3/, while it is equally active in stimulating intestinal calcium absorption. On the other hand, it is much less active (one-third to one-fifth) than 25-hydroxyvitamin D/sub 3/ in the mobilization of calcium from bone. In both the intestinal and bone responses, 1..cap alpha..-hydroxyvitamin D/sub 2/ (312 pmol) is active in nephrectomized rats while 15-hydroxyvitamin D/sub 3/ is not.

  6. Transport of. cap alpha. -aminoisobutyric acid into rat parotid after X-irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Bodner, Lipa

    1989-04-01

    Rat parotid gland exposed to 20 Gy X-irradiation exhibits functional alteration 3 days after exposure. The flow rate of saliva and the uptake of ..cap alpha..-aminoisobutyric acid by the gland was reduced to 50% of values for the control non-irradiated glands. When the same gland was studied in an in vitro system it functioned normally. K/sup +/ release and ..cap alpha..-aminoisobutyric acid uptake by the irradiated dispersed acinar cells was comparable to the control. Transport alteration from the circulatory system into the parotid gland may cause the initial radiation-induced damage.

  7. Measurement of the absolute power of subcritical reactors by the Feinman-. cap alpha. method

    Energy Technology Data Exchange (ETDEWEB)

    Sapozhnikov, V.V.; Tyrkich, E.A.; Lukhanin, A.P.; Okhapkin, V.P.

    1974-01-01

    The effect is examined of delay between time intervals on the value of the power measured, using the Feynman-..cap alpha.. method. The absolute power is shown to be practically independent of the delay value at time intervals less than 10/sup -2/ sec.

  8. Effect of heating rate on temperature of titanium alloy (. cap alpha. +. beta. ). -->. beta. transformaton

    Energy Technology Data Exchange (ETDEWEB)

    Gridnev, V.N.; Ivasishin, O.M.; Markovskij, P.E. (AN Ukrainskoj SSR, Kiev. Inst. Metallofiziki)

    1985-01-01

    The effect of doping of two-phase titaniums alloys and morphology of initial structure on the Tsub(t) temperature shift value of (..cap alpha..+..beta..)..--> beta.. transformation depending on heating rate is investigated. It has been found that the Tsub(t) shift occurs in the strictly determined temperature range depending on chemical alloy composition. The Tsub(t) shift is directly proportional to the Ksub(..beta..) coefficient applied as a quantitative alloying characteristic as well as a dimensional factor equal either to the plate thickness or the ..cap alpha..-phase globule diameter depending on the type of initial structure. In the limits of this temperature range the (..cap alpha..+..beta..)..--> beta..-transformation occurs completely according to the diffusion mechanism. The critical heating rate at which maximum permissible Tsub(t) value is attained and above which its stabilization is observed is determined by the same parameters - the alloy doping degree characterized by the Ksub(..beta..) coefficient and the ..cap alpha..-phase crystal dimensions in the initial structure.

  9. Lyman-alpha emission in star-forming galaxies

    Science.gov (United States)

    Hartmann, Lee W.; Huchra, John P.; Geller, Margaret J.; O'Brien, Paul; Wilson, Robert

    1988-01-01

    IUE observations of five blue, low-metallicity, star-forming galaxies sufficiently redshifted to permit detection of Lyman-alpha are reported. The galaxies with metallicities 0.1 time solar or more have weak or absent Lyman-alpha emission. There is evidence for increasing Lyman-alpha emission with decreasing metallicity. The reduction of Lyman-alpha fluxes from recombination values is attributed to absorption of multiply scattered Lyman-alpha by dust.

  10. Agonist-promoted desensitization and phosphorylation of. cap alpha. /sub 1/-adrenergic receptors coupled to stimulation of phosphatidylinositol metabolism

    Energy Technology Data Exchange (ETDEWEB)

    Leeb-Lundberg, L.M.F.; Cotecchia, S.; Caron, M.G.; Lefkowitz, R.J.

    1986-03-05

    In the DDT/sub 1/ MF-2 hamster vas deferens smooth muscle cell line the ..cap alpha../sub 1/-adrenergic receptor (..cap alpha../sub 1/-AR) agonist norepinephrine (NE) promotes rapid attenuation of ..cap alpha../sub 1/-AR-mediated phosphatidylinositol (PI) metabolism which is paralleled by rapid phosphorylation of the ..cap alpha../sub 1/-AR. Cells were labeled by incubation with /sup 32/P/sub i/. Coincubation with NE (100 ..mu..M) significantly increases the rate of /sup 32/P-labeling of both PI and phosphatidic acid. Pretreatment of cells with 100 ..mu..M NE (in the presence of 1 ..mu..M propranolol to prevent ..beta..-AR interactions) results in a drastic attenuation of the NE response on PI metabolism. ..cap alpha../sub 1/-AR from labeled cells can be solubilized and purified by affinity chromatography on Affigel-A55414 and wheat germ agglutinin agarose chromatography. SDS-PAGE of purified ..cap alpha../sub 1/-AR shows a NE-promoted increase in phosphorylation of the M/sub r/ 80K ligand binding peptide. Stoichiometry of phosphorylation increases from approx. 1 mol phosphate/mol ..cap alpha../sub 1/-AR in the basal condition to approx. 2.5 after NE treatment. Both desensitization and phosphorylation are rapid being maximal within 10-20 min of agonist exposure. These results together with previous findings that phorbol esters promote rapid ..cap alpha../sub 1/-AR uncoupling and phosphorylation suggest that receptor phosphorylation is an important mechanism of regulation of ..cap alpha../sub 1/-AR receptor responsiveness.

  11. High Energy Emission from the Polar Cap The Slot Gap Revisited

    CERN Document Server

    Muslimov, A G

    2003-01-01

    The characteristics of the high-energy emission from polar cap accelerators will be discussed. Particles accelerated in the "slot gap" near the polar cap rim will reach altitudes of several stellar radii before initiating pair cascades, producing a wide hollow cone of emission in young pulsars and some millisecond pulsars. Model X-ray and gamma-ray spectra and pulse profiles, based on Monte-Carlo simulations of polar cap pair cascades, will be presented.

  12. Kinetic model of Bacillus stearothermophilus. cap alpha. -amylase under process conditions

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, W.E.; Teague, W.M.

    1988-11-01

    A model is presented describing starch hydrolysis by Bacillus stearothermophilus ..cap alpha..-amylase at temperatures of 90 to 115/sup 0/C and substrate concentrations of 24 to 36% solids. First order kinetics adequately describe both the enzyme decay and starch hydrolysis reactions. Quantitation of temperature, pH, added calcium and substrate concentration interactive effects on the first order rate constants is aided by applying standard statistical techniques of experimental design and data analysis. A method for determining residual ..cap alpha..-amylase activity in liquefact based on the Phadebas dye release assay, and an osmometry method for determining degree of liquefact hydrolysis are described. Computer implementation of the model allows rapid graphical visualization as well as screening of ideas for improved starch hydrolysis processes.

  13. Radiation electromagnetic effect in germanium crystals under high-energy. cap alpha. -particle irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Kikoin, I.K.; Babichenko, V.S.; Kikoin, L.I.; Lazarev, S.D.; Rzhanov, A.E.; Filippov, V.I.

    1984-05-01

    Results of experimental investigation into radiation electromagnetic effect (REM) in samples of germanium crystals under approximately 40 MeV ..cap alpha..-particle irradiation in a cyclotron are presented. A high level of excitation, volumetric character of generation of non-equilibrium carriers and formation of defects as well as the form of their spatial distribution are shown to result in some peculiarities of the EMF of the REM effect on the particle flux, fluence and sample parameters. Agreement of theoretical calculations, conducted with account of specificity of ..cap alpha..-particle interaction with a crystal, and experimental data is obtained. It is revealed that the REM effect can be applied in obtaining data on spatial distribution of non-equilibrium carrier concentrations along the particle trajectory in the crystal.

  14. Radiation-electromagnetic effect in germanium crystals irradiated with high-energy. cap alpha. particles

    Energy Technology Data Exchange (ETDEWEB)

    Kikoin, I.K.; Babichenko, V.S.; Kikoin, L.I.; Lazarev, S.D.; Rzhanov, A.E.; Filippov, V.I.

    1984-05-01

    An experimental investigation was made of the radiation-electromagnetic effect in germanium crystals irradiated in a cyclotron with ..cap alpha.. particles of energies up to 40 MeV. The high excitation rate, the bulk nature of generation of nonequilibrium carriers and defects, and their spatial distributions gave rise to several special features in the dependence of the emf due to the radiation-electromagnetic effect on the particle flux, fluence, and parameters of samples. Theoretical calculations carried out allowing for the specific nature of the interaction of ..cap alpha.. particles with crystals agreed well with the experimental results. The radiation-electromagnetic effect could be used to obtain information on the nature of the spatial distribution of the density of nonequilibrium carriers along the trajectory of a particle in a crystal.

  15. Factorization of the fragmentation cross sections in relativistic pA and. cap alpha. A interactions

    Energy Technology Data Exchange (ETDEWEB)

    Abashidze, L.I.; Avdeichikov, V.V.; Beznogikh, G.G.; Bogatin, V.I.; Budilov, V.A.; Gorshkov, N.L.; Zlomanchuk, Y.; Zhidkov, N.K.; Lozhkin, O.V.; Mruvchinski, S.

    1985-08-01

    We have experimentally demonstrated the factorization of the cross sections for production of the isotopes /sup 3//sup ,//sup 4/He with kinetic energy T> or approx. =100 MeV emitted at an angle 90/sup 0/ in the lab from the nuclei C, Cu, and Au in bombardment by ..cap alpha.. particles with energy 3.33 GeV/nucleon and by protons with energy 6.6 GeV.

  16. Accumulation of glycation products in. cap alpha. -H pig lens crystallin and its bearing to diabetic cataract genesis

    Energy Technology Data Exchange (ETDEWEB)

    Vidal, P.; Cabezas-Cerrato, J.

    1988-01-01

    The incorporation of /sup 11/C-glucose in native pig crystalline by in vitro incubation was found, after subsequent dialysis, to affect all 5 classes of crystallin separated by Sepharose CL-6B column chromatography. Though the radioactivity of the ..cap alpha..-H fraction was three times greater than that of any of the others, autoradiographs of SDS-PAGE gels showed /sup 11/C-glucose adducts to be present in all soluble protein subunits, without there being any evidence of preferential glycation of the ..cap alpha..-H subunits. The concentration of stable glycation products in the ..cap alpha..-H chromatographic fraction of soluble crystallins is suggested to be due the addition of glycated material to this fraction as result of glycation-induced hyperaggregation, and not because the ..cap alpha..-H subunits were especially susceptible to glycation.

  17. Estrogen receptor binding radiopharmaceuticals: II. Tissue distribution of 17. cap alpha. -methylestradiol in normal and tumor-bearing rats

    Energy Technology Data Exchange (ETDEWEB)

    Feenstra, A.; Vaalburg, W.; Nolten, G.M.J.; Reiffers, S.; Talma, A.G.; Wiegman, T.; van der Molen, H.D.; Woldring, M.G.

    1983-06-01

    Tritiated 17..cap alpha..-methylestradiol was synthesized to investigate the potential of the carbon-11-labeled analog as an estrogen-receptor-binding radiopharmaceutical. In vitro, 17..cap alpha..-methylestradiol is bound with high affinity to the cytoplasmic estrogen receptor from rabbit uterus (K/sub d/ = 1.96 x 10/sup -10/M), and it sediments as an 8S hormone-receptor complex in sucrose gradients. The compound shows specific uptake in the uterus of the adult rat, within 1 h after injection. In female rats bearing DMBA-induced tumors, specific uterine and tumor uptakes were observed, although at 30 min the tumor uptake was only 23 to 30% of the uptake in the uterus. Tritiated 17..cap alpha..-methylestradiol with a specific activity of 6 Ci/mmole showed a similar tissue distribution. Our results indicate that a 17 ..cap alpha..-methylestradiol is promising as an estrogen-receptor-binding radiopharmaceutical.

  18. Determination of the M-matrix in d-. cap alpha. elastic scattering from a complete set of experiments

    Energy Technology Data Exchange (ETDEWEB)

    Elsener, K.; Grueebler, W.; Sperisen, F.; Ghazi-Wakili, K.; Koenig, V.; Schmelzbach, P.A.; Vuaridel, B.; Bittcher, M.; Singy, D.; Ulbricht, J.

    1988-05-02

    Six polarization transfer coefficients of the d-..cap alpha.. elastic scattering have been measured at an incident deuteron energy of 11.9 MeV and a scattering angle theta/sub lab/ = 37.3/sup 0/. Together with earlier data on cross section and analyzing powers, a complete set of measurements allows to deduce the d-..cap alpha.. M-matrix directly from experiment.

  19. Control of. cap alpha. -amylase mRNA accumulation by gibberellic acid and calcium in barley aleurone layers

    Energy Technology Data Exchange (ETDEWEB)

    Deikman, J.; Jones, R.L.

    1985-01-01

    Pulse-labeling of barley (Hordeum vulgare L. cv Himalaya) aleurone layers incubated for 13 hours in 2.5 micromolar gibberellic acid (GA/sub 3/) with or without 5 millimolar CaCl/sub 2/ shows that ..cap alpha..-amylase isozymes 3 and 4 are not synthesized in vivo in the absence of Ca/sup 2 +/. No difference was observed in ..cap alpha..-amylase mRNA levels between layers incubated for 12 hours in 2.5 micromolar GA/sub 3/ with 5 millimolar CaCl/sub 2/ and layers incubated in GA/sub 3/ alone. RNA isolated from layers incubated for 12 hours in GA/sub 3/ with and without CA/sup 2 +/. A cDNA clone for ..cap alpha..-amylase was isolated and used to measure ..cap alpha..-amylase mRNA levels in aleurone layers incubated in the presence and absence of Ca/sup 2 +/ was translated in vitro and was found to produce the same complement of translation products regardless of the presence of Ca/sup 2 +/ in the incubation medium. Immunoprecipitation of translation products showed that the RNA for ..cap alpha..-amylase synthesized in Ca/sup 2 +/-deprived aleurone layers was translatable. Ca/sup 2 +/ is required for the synthesis of ..cap alpha..-amylase isozymes 3 and 4 at a step after mRNA accumulation and processing.

  20. Actin capping protein alpha maintains vestigial-expressing cells within the Drosophila wing disc epithelium.

    Science.gov (United States)

    Janody, Florence; Treisman, Jessica E

    2006-09-01

    Tissue patterning must be translated into morphogenesis through cell shape changes mediated by remodeling of the actin cytoskeleton. We have found that Capping protein alpha (Cpa) and Capping protein beta (Cpb), which prevent extension of the barbed ends of actin filaments, are specifically required in the wing blade primordium of the Drosophila wing disc. cpa or cpb mutant cells in this region, but not in the remainder of the wing disc, are extruded from the epithelium and undergo apoptosis. Excessive actin filament polymerization is not sufficient to explain this phenotype, as loss of Cofilin or Cyclase-associated protein does not cause cell extrusion or death. Misexpression of Vestigial, the transcription factor that specifies the wing blade, both increases cpa transcription and makes cells dependent on cpa for their maintenance in the epithelium. Our results suggest that Vestigial specifies the cytoskeletal changes that lead to morphogenesis of the adult wing.

  1. Mapping High-Velocity H-alpha and Lyman-alpha Emission from Supernova 1987A

    Science.gov (United States)

    France, Kevin; McCray, Richard; Fransson, Claes; Larsson, Josefin; Frank, Kari A.; Burrows, David N.; Challis, Peter; Kirshner, Robert P.; Chevalier, Roger A.; Garnavich, Peter; Heng, Kevin; Lawrence, Stephen S.; Lundqvist, Peter; Smith, Nathan; Sonneborn, George

    2015-01-01

    We present new Hubble Space Telescope images of high-velocity H-alpha and Lyman-alpha emission in the outer debris of SN 1987A. The H-alpha images are dominated by emission from hydrogen atoms crossing the reverse shock. For the first time we observe emission from the reverse shock surface well above and below the equatorial ring, suggesting a bipolar or conical structure perpendicular to the ring plane. Using the H-alpha imaging, we measure the mass flux of hydrogen atoms crossing the reverse shock front, in the velocity intervals (-7,500 < V(sub obs) < -2,800 km/s) and (1,000 < V(sub obs) < 7,500 km/s), ?M(sub H) = 1.2 × 10(exp -3) M/ y. We also present the first Lyman-alpha imaging of the whole remnant and new Chandra X-ray observations. Comparing the spatial distribution of the Lyman-alpha and X-ray emission, we observe that the majority of the high-velocity Lyman-alpha emission originates interior to the equatorial ring. The observed Lyman-alpha/H-alpha photon ratio, R(L-alpha/H-alpha) approx. = 17, is significantly higher than the theoretically predicted ratio of approx. = 5 for neutral atoms crossing the reverse shock front. We attribute this excess to Lyman-alpha emission produced by X-ray heating of the outer debris. The spatial orientation of the Lyman-alpha and X-ray emission suggests that X-ray heating of the outer debris is the dominant Lyman-alpha production mechanism in SN 1987A at this phase in its evolution.

  2. Fast diffusion and electrotransport of cobalt, iron and nickel in. cap alpha. -Y

    Energy Technology Data Exchange (ETDEWEB)

    Okafor, I.C.I.; Carlson, O.N. (Ames Lab., IA (USA))

    1982-03-01

    The diffusion and electrotransport properties of cobalt, iron and nickel in ..cap alpha..-Y were determined. Measurements over the temperature range 1290-1600 K showed that all three solutes have high mobilities and that the diffusivities are of the order of 10/sup -5/ - 10/sup -6/ cm/sup 2/ s/sup -1/. Plots of lnD versus 1/T for each solute at several different temperatures gave activation energies for diffusion between 80 and 97 kJ mol/sup -1/. Negative values were obtained for the effective valence of each solute.

  3. Gravimetric determination and radiochemical separation of palladium(II) with ethyl-. cap alpha. -isonitrosoacetoacetate

    Energy Technology Data Exchange (ETDEWEB)

    Manwati, S.J.; Sawant, A.D. (Institute of Science, Bombay (India). Inorganic and Nuclear Chemistry Lab.)

    1984-10-01

    The use of ethyl-..cap alpha..-isonitrosoacetoacetate for the determination of palladium is reported. Pd can be estimated quantitatively from 0.5M to 2M HCl solution. Accurate results are obtained in 1M solution with an accuracy better than 1%. Decontamination values against platinum and other metals usually associated with Pd are greater than 10/sup 5/. The time required for gravimetric determination is about an hour, for radiochemical separation about 25 min and the recovery is better than 90%.

  4. Mapping High-velocity H-alpha and Lyman-alpha Emission from Supernova 1987A

    OpenAIRE

    France, Kevin; McCray, Richard; Fransson, Claes; Larsson, Josefin; Frank, Kari A.; Burrows, David N.; Challis, Peter; Kirshner, Robert P.; Chevalier, Roger A.; Garnavich, Peter; Heng, Kevin; Lawrence, Stephen S.; Lundqvist, Peter; Smith, Nathan; Sonneborn, George

    2015-01-01

    We present new {\\it Hubble Space Telescope} images of high-velocity H-$\\alpha$ and Lyman-$\\alpha$ emission in the outer debris of SN~1987A. The H-$\\alpha$ images are dominated by emission from hydrogen atoms crossing the reverse shock. For the first time we observe emission from the reverse shock surface well above and below the equatorial ring, suggesting a bipolar or conical structure perpendicular to the ring plane. Using the H$\\alpha$ imaging, we measure the mass flux of hydrogen atoms cr...

  5. Secondary. cap alpha. -deuterium kinetic isotope effects in solvolyses of ferrocenylmethyl acetate and benzoate in ethanol

    Energy Technology Data Exchange (ETDEWEB)

    Sutic, D. (Univ. of Zagreb, Yugoslavia); Asperger, S.; Borcic, S.

    1982-12-17

    Secondary ..cap alpha..-deuterium kinetic isotope effects (KIE) in solvolyses of ferrocenyldideuteriomethyl acetate and benzoate were determined in 96% (v/v) ethanol, at 25/sup 0/C, as k/sub H//k/sub D/ = 1.24 and 1.26, respectively. The KIEs were also determined in the presence of 0.1 mol dm/sup -3/ lithium perchlorate: the k/sub H//k/ sub D/ values were 1.23 and 1.22 for acetate and benzoate complexes, respectively. The maximum KIE for the C-O bond cleavage of a primary substrate is as large as, or larger than, that of secondary derivatives, which is estimated to be 1.23 per deuterium. The measured KIE of about 12% per D therefore represents a strongly reduced effect relative to its maximum. The solvolyses exhibit ''a special salt effect''. This effect indicates the presence of solvent-separated ion pairs and the return to tight pairs. As the maximum KIE is expected in solvolyses involving transformation of one type of ion pair into another, the strongly reduced ..cap alpha..-D KIE supports the structure involving direct participation of electrons that in the ground state are localized at the iron atom. The alkyl-oxygen cleavage is accompanied by 10-15% acyl-oxygen cleavage.

  6. No effect of 5-fluorouracil on the properties of purified. cap alpha. -amylase from barley half-seeds

    Energy Technology Data Exchange (ETDEWEB)

    Rodaway, S.J.; Kende, H.

    1978-01-01

    Amylase has been purified from de-embryonated seeds of barley (Horedeum vulgare L. cv. Betzes) which have been incubated on 10/sup 6/M gibberellic acid (GA/sub 3/) following 3 days of imbibition in buffer. Incubation of the half-seeds in up to 10/sup -2/ M 5-fluorouracil (5-FU) during the entire incubation period, including imbibition, had no effect on any of the following characteristics of purified ..cap alpha..-amylase: thermal stability in the absence of calcium, molecular weight of the enzyme, isozyme composition, specific activity, or the amount of ..cap alpha..-amylase synthesized by the aleurone tissue. The synthesis of rRNA and tRNA was strongly inhibited by 5-FU, indicating that the analog had entered the aleurone cells. These results are not in agreement with those of Carlson (Nature New Biology 237: 39-41 (1972)) who found that treatment of barley aleurone with 10/sup -4/ M 5-FU to the addition of GA/sub 3/ resulted in decreased thermal stability of GA/sub 3/-induced ..cap alpha..-amylase and who interpreted this as evidence that the mRNA for ..cap alpha..-amylase was synthesized during the imbibition of the aleurone tissue and independently of gibberellin action. Results of the present experiments indicate that the thermal stability of highly purified ..cap alpha..-amylase is not altered by treatment of barley half-seeds with 5-FU, and that 5-FU cannot be used as a probe to examine the timing of ..cap alpha..-amylase mRNA synthesis.

  7. (p,. cap alpha. ) reaction on /sup 98/Mo and /sup 100/Mo. [12. 3 and 15 Mev, angular distributions

    Energy Technology Data Exchange (ETDEWEB)

    Avrigeanu, V.; Bucurescu, D.; Constantinescu, G.; Ivascu, M.; Popescu, D.; Teodorescu, R.

    1975-01-01

    Levels of /sup 95/Nb and /sup 97/Nb were studied with the /sup 98/Mo(p, ..cap alpha..) reaction at 12.3 MeV and the /sup 100/Mo(p, ..cap alpha..) reaction at 15 MeV incident energy, respectively. Angular distributions were determined for the most prominent levels below 2 MeV, and compared with DWBA calculations based on a triton-cluster form factor. The results are compared with level schemes provided by other nuclear reactions. (auth)

  8. K. cap alpha. sup(h) hypersatellite spectrum and K shell double photoionization cross-section for Ar

    Energy Technology Data Exchange (ETDEWEB)

    Mikkola, E.; Ahopelto, J. (Helsinki University of Technology, Espoo (Finland). Lab. of Physics)

    1983-04-01

    The K..cap alpha..sup(h) hypersatellite spectrum of gaseous Ar has been measured in photon excitation with a plane crystal Bragg spectrometer. The experimental energy of K..cap alpha../sub 2/sup(h) line is obtained. The result is in good agreement with available theoretical calculations. The K shell double photoionization cross-section is estimated from the measured hypersatellite intensity and it is compared with existing theoretical calculations based on the shake theory and correlated wave functions.

  9. CARBON EMISSIONS CAPS AND THE IMPACT OF A RADICAL CHANGE IN NUCLEAR ELECTRICITY COSTS

    Directory of Open Access Journals (Sweden)

    Benjamin D. Leibowicz

    2013-01-01

    Full Text Available In this study we analyze the impact of a radical change in nuclear electricity costs on the optimal electricity generation technology mix (EGTM and constrain the value of information (VOI on future nuclear costs. We consider three nuclear cost events and four carbon emissions caps. We develop a two-stage framework for energy-economic model MARKAL to eliminate foresight of future nuclear cost movements. We examine how the EGTM responds to these movements under alternative caps and analyze how these movements affect the cost of each cap. We define the expected savings from perfect foresight (ESPF, an upper bound on the VOI. We found that with current technologies, carbon mitigation that does not rely heavily on nuclear electricity is economically insensible. The Strong Cap is extremely costly because it restricts flexibility to respond to cost signals in choosing among technologies. The ESPF is highest under the Medium Cap by a substantial margin.

  10. Determination of the density of states of. cap alpha. -Si:H using the field effect

    Energy Technology Data Exchange (ETDEWEB)

    Goodman, N B; Fritzsche, H; Ozaki, H

    1979-01-01

    A new iterative computer method has been devised for obtaining N(E), the density of gap states, from field effect data without using simplifying approximations. Analysis shows that equally good fits to the data can be obtained over a range of values of the ratio of electron and hole contributions to the conductivity in the bulk and of the field voltage needed to obtain flat bands. The present experimental accuracy is not sufficient to discern detailed structure in N(E). The validity of assuming a parallel shift of the mobility edge with the potential near the interface is being questioned. Field effect data on undoped glow-discharge ..cap alpha..-Si:H subjected to the Staebler-Wronski cycle of illumination and heat treatment are presented and analyzed.

  11. Twisted accretion discs: Pt. 4. Alignment in polytropic discs and low. cap alpha. limit

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, S.

    1988-07-01

    Twisted thin accretion discs are of interest in explaining long-term periodicities in X-ray binaries, the eclipse in Epsilon Aurigae, and perhaps precessing radio jets and possible warped molecular outflows in star-forming regions. Earlier results used isothermal discs to determine the alignment radius, Rsub(a). Now we see how polytropic discs effect earlier results for discs around compact objects and around close binaries. We find that Rsub(a) for polytropic discs can be up to an order of magnitude larger, depending on the polytropic index, the viscosity parameter and the precession mechanism. There is little change in the earlier conclusion that the case for alignment in Her X-1 is marginal, while there is substantial alignment in epsilon Aur. A lower limit is put on ..cap alpha.. for isothermal discs, which is expected to hold for polytropic discs as well. A bound is put on the energy of the perturbed flows.

  12. Studies on the 1. cap alpha. ,25-dihydroxycholecalciferol-like activity in a calcinagenic plant, Cestrum diurnum, in the chick

    Energy Technology Data Exchange (ETDEWEB)

    Wasserman, R.H. (Cornell Univ., Ithaca, NY); Corradino, R.A.; Krook, L.; Hughes, M.R.; Haussler, M.R.

    1976-04-01

    Cestrum diurnum (day-blooming jessamine) has been proposed to cause calcinosis in horses and cattle in Florida. The present studies investigated some physiological properties of the plant, using the chick as the experimental animal. The inclusion of dried leaf powder in a rachitogenic diet restored intestinal calcium-binding protein synthesis (CaBP) and increased calcium absorption in the cholecalciferol-deficient chick. The estimated level of cholecalciferol-equivalents in the dried leaf was about 30,000 to 35,000 IU/kg. Most of the activity was extractable with methanol : chloroform (2:1), indicating that the major cholecalciferol-like component in C. diurnum was different from the water soluble factor(s) in Solanum malacoxylon. The time course of effect of C. diurnum extract in rachitic chicks was similar to that of 1,25-dihydroxycholecalciferol but the former had a longer lag time. The strontium fed chick, in which the kidney 25-hydroxycholecaliciferol-1..cap alpha..-hydroxylase is inhibited, responded to C. diurnum extract, confirming the 1..cap alpha..,25-dihydroxycholecalciferol-like character of the Cestrum factor. The extract also appeared to interact with the intestinal 1..cap alpha..,25-dihydroxycholecalciferol cytosol receptor although this observation is preliminary. These findings indicate that the 1..cap alpha..,25-dihydroxycholecalciferol-like principle in C. diurnum may cause excessive calcium and phosphate absorption leading to calcinosis.

  13. Effects of thyroid status on presynaptic. cap alpha. 2-adrenoceptor and. beta. -adrenoceptor binding in the rat brain

    Energy Technology Data Exchange (ETDEWEB)

    Atterwill, C.K.; Bunn, S.J.; Atkinson, D.J. (Development Neurobiology Unit, London (UK). Inst. of Neurology); Smith, S.L.; Heal, D.J. (Radcliffe Infirmary, Oxford (UK))

    1984-01-01

    The effect of thyroid status on noradrenergic synaptic function in the mature brain was examined by measuring presynaptic ..cap alpha..2- and postsynaptic ..beta..-adrenoceptors. Repeated triiodothyronine (T/sub 3/) administration to rats (100..mu..g/kg x 14 days hyperthyroid) caused an 18% increase in striatal ..beta..-adrenoceptors as shown by (/sup 3/H)-dihydroalprenolol binding with no change in membranes from cerebral cortex or hypothalamus. In contrast, hypothyroidism (propylthiouracil, PTU x 14 days) produced significant 12% and 30% reductions in striatal and hypothalamic ..beta..-adrenoceptors respectively with no change in the cerebral cortex. Presynaptic ..cap alpha..2-adrenoceptor function was measured in the two dysthyroid states using the clonidine-induced hypoactivity model. Experimental hyperthyroidism increased the degree of clonidine-induced hypoactivity, and suggests increased presynaptic ..cap alpha..2-adrenoceptor function compared with control rats, whereas hypothyroidism suppressed presynaptic ..cap alpha..2-adrenoceptor function. These results show firstly that changes of thyroid status in the mature rat may produce homeostatic alterations at central noradrenergic synapses as reflected by changes in pre- and postsynaptic adrenoceptor function. Secondly, there appear to be T/sub 3/-induced changes in ..beta..-adrenoceptors in the striatum where changes in dopaminergic neuronal activity have previously been demonstrated.

  14. K alpha line emission during solar X-ray bursts

    Science.gov (United States)

    Phillips, K. J. H.; Neupert, W. M.

    1973-01-01

    The expected flux of K alpha line emission from sulfur, argon, calcium, and iron is calculated during both thermal and nonthermal solar X-ray events. Such emission is shown to be weak during the course of most of the nonthermal hard X-ray bursts that Kane and Anderson (1970) have observed. If Compton backscattering is significant at high energies, the flux is reduced still further for disk flares, but it is noted that the strong, near-limb burst of June 26 would have produced about 100 photons /sq cm/sec of sulfur and iron K alpha emission. The impulsive hard X-ray bursts may in general be too short-lived for much K alpha emission. It may be noted that sulfur K alpha emission in particular depends sensitively on the lower-energy limit of the nonthermal electron spectrum, assuming such a sharply defined boundary exists. During soft X-ray bursts, when temperatures of a few 10 to the 7th power K are obtained, K alpha emission from certain iron ions, specifically Fe XVIII-XXIII, may be important.

  15. Optimization of cold K-alpha emission using copper foams

    Science.gov (United States)

    Hussein, Amina; Hager, Jonathan; Flippo, Kirk

    2015-11-01

    Experiments were conducted at the Trident Laser Facility to increase the conversion efficiency of short-pulse, copper K-alpha x-ray backlighter sources. New target designs using copper foams are in development to investigate the role of underdense/near-critical density targets on the optimization of cold K-alpha emission. K-alpha emission was measured using Highly Ordered Pyrolytic Graphic (HOPG) and imaged with a toroidally bent quartz crystal to determine uniformity, spatial resolution and conversion efficiency of the new designs. Results from this experiment will help inform the development of short-pulse Cu K-alpha back-lighters on facilities like Omega, OmegaEP and the NIF, with a particular emphasis on creating advanced narrow-band backlighter sources capable of producing strong signal to noise with high x-ray fluxes.

  16. Toxin a from Clostridium difficile binds to rabbit erythrocyte glycolipids with therminal Gal. cap alpha. 1-3Gal. beta. 1-4GlcNaC sequences

    Energy Technology Data Exchange (ETDEWEB)

    Clark, G.F.; Krivan, H.; Wilkins, T.; Smith, D.F.

    1987-05-01

    Toxin A is one of two clostridial toxins implicated as the causative agent of pseudomembranous colitis in patients undergoing postoperative antibiotic therapy. Evidence that the carbohydrate binding determinant for this toxin is a glycoconjugate(s) with non-reducing Gal..cap alpha..1-3Gal..beta..1-4GlcNAc has recently been reported. Specific agglutination of rabbit erythrocytes by Toxin A is inhibited by bovine thyroglobulin and prevented by pretreatment of cells with ..cap alpha..-galactosidase. Total lipid extracts from rabbit erythrocytes were subjected to thin layer chromatography and the chromatogram overlaid with purified /sup 125/I-labeled Toxin A. Two major and several minor toxin-binding glycolipids were detected following autoradiography. The major toxin-binding glycolipids were identified as pentasaccharide- and decasaccharide-ceramides expressing terminal Gal..cap alpha..1-3Gal..beta..1-4GlcNAc sequences. Treatment of the toxin-binding glycolipids with ..cap alpha..-galactosidase abolished binding. Forsmann glycolipid, globoside, Gal..cap alpha..1-4 Gal..beta..1-4Glc-cer, and Gal..cap alpha..1-3Gal..beta..1-4Glc-cer did not bind the toxin. These observations are consistent with the proposed carbohydrate specificity of the toxin for the non-reducing terminal sequence, Gal..cap alpha..1-3Gal..beta..1-4GlcNAc.

  17. Sulphidation behaviour of. beta. -NiAl-. cap alpha. -Cr pseudobinary alloys

    Energy Technology Data Exchange (ETDEWEB)

    Godlewska, E.; Godlewski, K.; Mrowec, S.

    1987-03-01

    The sulphidation behaviour of alloys belonging to the ..beta..-NiAl-..cap alpha..-Cr pseudobinary system was studied at S/sub 2/ pressures P/sub S2/ of 5-2 x 10/sup 3/ Pa and temperatures of 1173 and 1273 K. The alloys contained 0, 4, 10 and 20 at.% Cr and the atomic ratio of nickel to aluminium was always 1 to 1. Kinetic measurements were carried out in a thermogravimetric set-up. The sulphidation rate increased with temperature, S/sub 2/ pressure and chromium concentration in the alloy. The scale morphology and composition for each alloy studied were influenced by the sulphidation parameters. The scales were usually of a multiphase and multilayer nature with varying proportions of Al/sub 2/S/sub 3/, Ni/sub 3/S/sub 2/ and Cr/sub x/S. The innermost part of the scale was always rich in aluminium or aluminium and chromium, the amount of nickel being the highest on the surface. At 1273 K and P/sub S2/ = 5 Pa the scales on chromium-rich alloys consisted of Al/sub 2/S/sub 3/ and Cr/sub x/S only.

  18. Comparison of holocellulose,. cap alpha. -cellulose and lignin contents of trunk and branch wood of some conifers of Pakistan

    Energy Technology Data Exchange (ETDEWEB)

    Mahmood, A.; Mahmood, T.

    1985-01-01

    Samples of trunk and branchwood of 7 conifer species growing under forest conditions in Pakistan were analysed to evaluate the suitability of branchwood for the pulp and paper industries. Holocellulose content in the branchwood of Cedrus deodara, Juniperus polycarpos, Pinus halepensis and Pinus roxburghii-amerciana(.) was comparable with values for their truckwood. The branchwood of Abies prindrow, P. rotberghii and P. wallichiana contained less holocellusose than the trunkwood. The branchwood of A. pindrow, C. deodara, and P. roxburghii-americana contained less ..cap alpha..-cellulose than the trunkwood, but ..cap alpha..-cellulose contents were comparable in the other 4 species. The lignin contents of trunk and branchwood were comparable in A. pindrow, C. deodara and P. roxburghii-americana, but showed some variation in the other species. 5 references.

  19. Determination of arsenic, antimony, and bismuth in silicon using 200 keV. cap alpha. -particle backscattering

    Energy Technology Data Exchange (ETDEWEB)

    Hnatowicz, V.; Kvitek, J. (Ceskoslovenska Akademie Ved, Rez. Ustav Jaderne Fyziky); Krejci, P.; Rybka, V. (Tesla, Prague (Czechoslovakia)); Pelikan, L. (Technical University of Prague (Czechoslovakia). Dept. of Microelectronics)

    1982-11-16

    Concentration profiles of As, Sb, and Bi implanted into Si are studied using backscattering of the 200 keV ..cap alpha..-particles. A conventional ion implanter serves as a source of analyzing beam and the scattered particles are detected using a silicon surface barrier detector. Measured projected ranges R/sub P/ of implanted atoms are found to be in satisfactory agreement with theoretical predictions.

  20. Assay and properties of rat yolk sac 25-hydroxyvitamin D/sub 3/ 1. cap alpha. -hydroxylase

    Energy Technology Data Exchange (ETDEWEB)

    Paulson, S.K.; Phelps, M.; DeLuca, H.F.

    1986-11-04

    An in vitro assay has been developed for the rat yolk sac 25-hydroxyvitamin D/sub 3/ 1..cap alpha..-hydroxylase (1..cap alpha..-hydroxylase). The subcellular location and some properties of the enzyme are described. 1,25-Dihydroxyvitamin D/sub 3/ produced from incubations of yolk sac homogenates was extracted, purified by Sephadex LH-20 chromatography and straight- and reverse-phase high-performance liquid chromatography (HPLC), and measured by a competitive binding assay using chick intestinal receptor. The reaction is linear with time for up to 45 min at a substrate concentration of 80 ..mu..M and 4-6 mg/mL microsomal protein. The enzyme, located in the microsomes, requires molecular oxygen and NADPH. Metyrapone (1 x 10/sup -3/ M) was found to inhibit 1-hydroxylation, but a 90% carbon monoxide-10% oxygen atmosphere did not, leaving open the question of involvement of cytochrome P-450. Diphenyl-p-phenylenediamine, a lipid peroxidase inhibitor, inhibited 1..cap alpha..-hydroxylation.

  1. Extended Ly$\\alpha$ emission around quasars with eclipsing damped Ly$\\alpha$ systems

    CERN Document Server

    Fathivavsari, Hassan; Noterdaeme, Pasquier; Pâris, Isabelle; Finley, Hayley; López, Sebastian; Srianand, Raghunathan

    2016-01-01

    We present spectroscopic observations of six high redshift ($z_{\\rm em}$ $>$ 2) quasars, which have been selected for their Lyman $\\alpha$ (Ly$\\alpha$) emission region being only partially covered by a strong proximate ($z_{\\rm abs}$ $\\sim$ $z_{\\rm em}$) coronagraphic damped Ly$\\alpha$ system (DLA). We detected spatially extended Ly$\\alpha$ emission envelopes surrounding these six quasars, with projected spatial extent in the range 26 $\\le$ $d_{\\rm Ly\\alpha}$ $\\le$ 51 kpc. No correlation is found between the quasar ionizing luminosity and the Ly$\\alpha$ luminosity of their extended envelopes. This could be related to the limited covering factor of the extended gas and/or due to the AGN being obscured in other directions than towards the observer. Indeed, we find a strong correlation between the luminosity of the envelope and its spatial extent, which suggests that the envelopes are probably ionized by the AGN. The metallicity of the coronagraphic DLAs is low and varies in the range $-$1.75 $<$ [Si/H] $<...

  2. EU emissions trading. The need for cap adjustment in response to external shocks and unexpected developments?

    Energy Technology Data Exchange (ETDEWEB)

    Diekmann, Jochen [DIW, Berlin (Germany)

    2012-11-15

    In this paper the advantages and disadvantages of the various adaptation options will be discussed from an economic perspective. Firstly, the criteria for identifying a need for potentially legitimate adaptation should be investigated. Furthermore, the issue of appropriate timely intervention points prior to or within the trading period will be discussed. In what periods and scenarios are adjustments to the cap worthwhile from an economic perspective? To what extent could minimum prices or price ranges make sense? What role could a strategic reserve play? By addressing these issues, it will be fundamentally discussed as to how the emissions trading scheme could be further developed and strengthened by greater flexibility. After a brief characterisation of emissions trading in theory and practice in Chapter 2, Chapter 3 will identify potential external shocks and unexpected developments which may impair the functioning of an emissions trading scheme. The current problems of cap setting for the third trading period of the EU ETS will be described in Chapter 4. Against this background, cap adjustments will be discussed in Chapter 5, minimum and maximum prices in Chapter 6 and strategic reserves in emissions trading in Chapter 7. The conclusions are summarised in Chapter 8.

  3. PAH Emission Within Lyman Alpha Blobs

    CERN Document Server

    Colbert, James W; Teplitz, Harry; Francis, Paul; Palunas, Povilas; Williger, Gerard M; Woodgate, Bruce

    2010-01-01

    We present Spitzer observations of Lya Blobs (LAB) at z=2.38-3.09. The mid-infrared ratios (4.5/8um and 8/24um) indicate that ~60% of LAB infrared counterparts are cool, consistent with their infrared output being dominated by star formation and not active galactic nuclei (AGN). The rest have a substantial hot dust component that one would expect from an AGN or an extreme starburst. Comparing the mid-infrared to submillimeter fluxes (~850um or rest frame far infrared) also indicates a large percentage (~2/3) of the LAB counterparts have total bolometric energy output dominated by star formation, although the number of sources with sub-mm detections or meaningful upper limits remains small (~10). We obtained Infrared Spectrograph (IRS) spectra of 6 infrared-bright sources associated with LABs. Four of these sources have measurable polycyclic aromatic hydrocarbon (PAH) emission features, indicative of significant star formation, while the remaining two show a featureless continuum, indicative of infrared energy...

  4. Two alpha, three alpha and multiple heavy-ion radioactivities

    Energy Technology Data Exchange (ETDEWEB)

    Poenaru, D.N.; Ivascu, M. (Institute for Physics and Nuclear Engineering, Bucharest (Romania))

    1985-07-01

    New decay modes by spontaneous emission of two and three ..cap alpha.. particles and two identical or different heavy ions, are predicted. The analytical variant of the superasymmetric fission model is used to estimate the half lives.

  5. Lyman-alpha Emission From Cosmic Structure I: Fluorescence

    CERN Document Server

    Kollmeier, Juna A; Davé, Romeel; Gould, Andrew; Katz, Neal; Miralda-Escudé, Jordi; Weinberg, David H

    2009-01-01

    We present predictions for the fluorescent Lyman-alpha emission signature arising from photoionized, optically thick structures in Smoothed Particle Hydrodynamic (SPH) cosmological simulations of a Lambda-CDM universe using a Monte Carlo Lyman-alpha radiative transfer code. We calculate the expected Lyman-alpha image and 2-dimensional spectra for gas exposed to a uniform ultraviolet ionizing background as well as gas exposed additionally to the photoionizing radiation from a local quasar, after correcting for the self-shielding of hydrogen. As a test of our numerical methods and for application to current observations, we examine simplified analytic structures that are uniformly or anisotropically illuminated. We compare these results with recent observations. We discuss future observing campaigns on large telescopes and realistic strategies for detecting fluorescence owing to the ambient metagalactic ionization and in regions close to bright quasars. While it will take hundreds of hours on the current genera...

  6. Field emission properties of capped carbon nanotubes doped by alkali metals:a theoretical investigation

    Institute of Scientific and Technical Information of China (English)

    Jin Lei; Fu Hong-Gang; Xie Ying; Yu Hai-Tao

    2012-01-01

    The electronic structures and field emission properties of capped CNT55 systems with or without alkali metal atom adsorption were systematically investigated by density functional theory calculation.The results indicate that the adsorption of alkali metal on the center site of a CNT tip is energetically favorable.In addition,the adsorption energies increase with the introduction of the electric field.The excessive negative charges on CNT tips make electron emittance much easier and result in a decrease in work function.Furthermore,the inducing effect by positively charged alkali metal atoms can be reasonably considered as the dominant reason for the improvement in field emission properties.

  7. Demonstration of. cap alpha. -adrenoceptors in the rabbit bladder base and urethra with /sup 3/H-dihydroergocryptine ligand binding

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, B. (Department of Clinical Pharmacology, University Hospital of Lund, Sweden)

    1983-01-01

    The purpose of this work was to demonstrate the presence of ..cap alpha..-adrenoceptors in a crude membrane preparation made from rabbit bladder base and urethra. This was achieved by radioligand binding studies, using /sup 3/H-dihydro-..cap alpha..-ergocryptine (/sup 3/H-DHE) as the radioligand. The specific binding, i.e. the binding that could be inhibited by 10/sup -5/ M phentolamine, was saturable with 73 fmol /sup 3/H-DHE bound per mg membrane protein. Binding was at steady state after 60 min., and reversible. Rate constants for association and dissocation were 3x10/sup 7/ M/sup -1/ min./sup -1/, and 2x10/sup -2/ min./sup -1/, respectively. A number of compounds were tested for their abilities to compete with /sup 3/H-DHE for the binding sites. The relative affinity of some adrenoceptor agonists was (-)-adrenaline>(-)-noradrenaline much larger than (+-)-isoprenaline. Steroselectivity was shown, since (-)-noradrenaline had 42 times higher affinity than (+)-noradrenaline. Adrenoceptor antagonists inhibited /sup 3/H-DHE binding in the following order of potency: DHE>phentolamine much larger than (+-)-propranolol. The dissociation constant, Ksub(D), for DHE to the binding sites was estimated in three different ways. The constants were derived from saturation, competition, and kinetic studies, and gave Ksub(D) values of 1.1,1.4 and 0.7 nM, respectively. The results suggest that ..cap alpha..-adrenoceptors were labelled by /sup 3/H-DHE in the tissue homogenates.

  8. Broadband control of emission wavelength of InAs/GaAs quantum dots by GaAs capping temperature

    Energy Technology Data Exchange (ETDEWEB)

    Kaizu, Toshiyuki, E-mail: kaizu@crystal.kobe-u.ac.jp [Center for Supports to Research and Education Activities, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501 (Japan); Department of Electrical and Electronic Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501 (Japan); Matsumura, Takuya; Kita, Takashi [Department of Electrical and Electronic Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501 (Japan)

    2015-10-21

    We investigated the effects of the GaAs capping temperature on the morphological and photoluminescence (PL) properties of InAs quantum dots (QDs) on GaAs(001). The broadband tuning of the emission wavelength from 1.1 to 1.3 μm was achieved at room temperature by only adjusting the GaAs capping temperature. As the capping temperature was decreased, the QD shrinkage due to In desorption and In-Ga intermixing during the capping process was suppressed. This led to QDs with a high aspect ratio, and resultantly, the emission wavelength shifted toward the longer-wavelength side. In addition, the linearly polarized PL intensity elucidated anisotropic characteristics reflecting the shape anisotropy of the embedded QDs, in which a marked change in polarization anisotropy occurred at capping temperatures lower than 460 °C.

  9. Evolution of accretion disc flow in cataclysmic variables. 3. Outburst properties of constant and uniform-. cap alpha. model discs

    Energy Technology Data Exchange (ETDEWEB)

    Lin, D.N.C.; Faulkner, J. (Lick Observatory, Santa Cruz, CA (USA); California Univ., Santa Cruz (USA). Board of Studies in Astronomy and Astrophysics); Papaloizou, J. (Queen Mary Coll., London (UK). Dept. of Applied Mathematics)

    1985-01-01

    The investigation of accretion disc models relevant to cataclysmic-variable systems is continued. This paper examines the stability and evolution of some simple accretion disc models in which the viscosity is prescribed by an ad hoc uniform-..cap alpha.. model. It is primarily concerned with systems in which the mass-input rate from the secondary to the disc around the primary is assumed to be constant. However, initial calculations with variable mass-input rates are also performed. The time-dependent visual magnitude light-curves are constructed for cataclysmic binaries with a range of disc size, primary mass, mass-input rate, and magnitude of viscosity.

  10. How Lyman Alpha Emission Depends On Galaxy Stellar Mass

    CERN Document Server

    Oyarzún, Grecco A; González, Valentino; Mateo, Mario; Bailey, John I; Finkelstein, Steven L; Lira, Paulina; Crane, Jeffrey D; Olszewski, Edward W

    2016-01-01

    In this work, we show how the stellar mass (M) of galaxies affects the 3alpha equivalent width (EW) distribution. To this end, we design a sample of 629 galaxies in the M range 7.6 < logM/Msun < 10.6 from the 3D-HST/CANDELS survey. We perform spectroscopic observations of this sample using the Michigan/Magellan Fiber System, allowing us to measure Ly-alpha fluxes and use 3D-HST/CANDELS ancillary data. In order to study the Ly-alpha EW distribution dependence on M, we split the whole sample in three stellar mass bins. We find that, in all bins, the distribution is best represented by an exponential profile of the form dN(M)/dEW= A(M)exp(-EW/W0(M))/W0(M). Through a Bayesian analysis, we confirm that lower M galaxies have higher Ly-alpha EWs. We also find that the fraction A of galaxies featuring emission and the e-folding scale W0 of the distribution anti- correlate with M, recovering expressions of the forms A(M)= -0.26(.13) logM/Msun+3.01(1.2) and W0(M)= -15.6(3.5) logM/Msun +166(34). Th...

  11. Electron double ionization cross section in sodium obtained from K. cap alpha. sup(h) hypersatellite spectra

    Energy Technology Data Exchange (ETDEWEB)

    Lahtinen, J.; Keski-Rahkonen, O. (Laboratory of Physics, Helsinki University of Technology, Espoo, Finland)

    1983-05-01

    The K..cap alpha..sup(h) hypersatellite spectrum of Na metal has been measured in electron excitation with voltages from 4 to 25 kV. The spectrum shows lines with initial K/sup -2/ (K..cap alpha../sub 2/sup(h)) and K/sup -2/L/sup -1/ holes. The energies of these lines as well as the K/sup 2/ binding energy have been determined and compared with theoretical calculations. The intensity of the line group with K/sup -2/L/sup -1/ initial configuration relative to the K/sup -2/ group has been measured and found to be in agreement with simple shake-off calculation. The electron double ionization cross section (EDC) of the K-shell has been determined from both thick and thin target measurements using the method developed by Saijonmaa and Keski-Rahkonen, and found to yield equivalent results. The EDC has also been calculated theoretically using classical and quantum mechanical binary encounter approximations as devised by Saijonmaa. Theory reproduces fairly well the magnitude and the atomic number dependence of the EDC whereas the shape of the EDC-curve as function of energy deviates clearly from observed values.

  12. A warmer policy for a colder climate: Can China both reduce poverty and cap carbon emissions?

    Science.gov (United States)

    Glomsrød, Solveig; Wei, Taoyuan; Aamaas, Borgar; Lund, Marianne T; Samset, Bjørn H

    2016-10-15

    Reducing global carbon dioxide (CO2) emissions is often thought to be at odds with economic growth and poverty reduction. Using an integrated assessment modeling approach, we find that China can cap CO2 emissions at 2015 level while sustaining economic growth and reducing the urban-rural income gap by a third by 2030. As a result, the Chinese economy becomes less dependent on exports and investments, as household consumption emerges as a driver behind economic growth, in line with current policy priorities. The resulting accumulated greenhouse gas emissions reduction 2016-2030 is about 60billionton (60Mg) CO2e. A CO2 tax combined with income re-distribution initially leads to a modest warming due to reduction in sulfur dioxide (SO2) emissions. However, the net effect is eventually cooling when the effect of reduced CO2 emissions dominates due to the long-lasting climate response of CO2. The net reduction in global temperature for the remaining part of this century is about 0.03±0.02°C, corresponding in magnitude to the cooling from avoiding one year of global CO2 emissions.

  13. Locating the Polar Cap Boundary of Postnoon Sector from Observations of 630.0 nm Auroral Emission at Zhongshan Station

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    We studied the ground observations of 630. 0 nm auroral emission at Zhongshan Station to de-termine the polar cap boundary with the latitudinal profile of emission intensity. The open-closed field lineboundary is assumed to lie at the boundary between polar rain and plasma sheet precipitation. We assumethat nonprecipitation-dependent sources of 630. 0 nm emission cause a spatially uniform luminosity in thepolar cap and that auroral zone luminosity is also spatially uniform. Therefore we determine the locationof the polar cap boundary of postnoon sector from the auroral emission data each time by finding the bestfit of the observations to a step function in latitude and we produce a time series of the location of the polarcap boundary. The average error of the practice in the paper is less than 0. 8 degree.

  14. Expression of herpes simplex virus. beta. and. gamma. genes integrated in mammalian cells and their induction by an. cap alpha. gene product

    Energy Technology Data Exchange (ETDEWEB)

    Sandri-Goldin, R.M.; Goldin, A.L.; Holland, L.E.

    1983-11-01

    The proteins of herpes simplex virus type 1 (HSV-1) form three kinetic groups termed ..cap alpha..,..beta..,and ..gamma.., whose synthesis is regulated in a cascade fashion, ..cap alpha.. products are synthesized first during infection, and they are required for synthesis of ..beta.. and ..gamma.. proteins. To examine the expression of several HSV-1 ..beta.. and ..gamma.. genes in the absence of ..cap alpha.. functions, we transferred into mammalian cells a plasmid containing a region of the HSV-1 genome that codes for only ..beta.. and ..gamma.. genes (0.315 to 0.421 map units). The authors found stable integration of at least one copy of the intact plasmid in each cell line. Four HSV-1 transcripts of the ..beta.. and ..gamma.. classes were transcribed constitutively in the cells, including the genes for glycoprotein B and DNA-binding protein. No constitutive synthesis of these two proteins could be demonstrated, however. The integrated HSV-1 genes responded to viral regulatory signals in that they could be induced by infection with HSV-1 mutants resulting in a high level of synthesis of both glycoprotein B and DNA-binding protein. The HSV-1 ..cap alpha.. gene product ICP4 was necessary for this induction, and it was found to be most efficient at a low multiplicity of infection. Functional expression of four genes was demonstrated in that the cell lines complemented infecting HSV-1 temperature-sensitive mutants. The same genes were not available for homologous recombination with infecting virus, however, since no recombinant wild-type virus could be detected. These data demonstrate that HSV-1 ..beta.. and ..gamma.. genes can be transcribed in the absence of ..cap alpha.. functions in mammalian cells, but that they still respond to HSV-1 regulatory signals such as the ..cap alpha.. gene product ICP4.

  15. Characteristics of the photelectromagnetic effect and properties of recombination centers in germanium single crystals irradiated with. cap alpha. particles

    Energy Technology Data Exchange (ETDEWEB)

    Babichenko, V.S.; Kikoin, L.I.; Lazarev, S.D.; Rzhanov, A.E.; Filippov, V.I.

    1984-01-01

    The spatial distribution of defects created in Ge crystals by irradiation with 40-MeV ..cap alpha.. particles was investigated. The distribution of the defects acting as recombination centers had a decisive influence on the diffusion-recombination processes in this semiconductor. The carrier-capture cross section of the recombination centers (sigmaapprox.10/sup -15/ cm/sup 2/) was determined. A concept of a recombination wall, which appeared in the region of a maximum of the radiation defect concentration, was introduced. The experimental data were compared with theoretical representations. This comparison demonstrated that an investigation of the photoelectromagnetic effect could give information both on the nature of the spatial distribution of radiation defects and on the recombination parameters of an irradiated semiconductor.

  16. Special features of photoelectromagnetic effect and properties of recombination centers in germanium single crystals irradiated by. cap alpha. particles

    Energy Technology Data Exchange (ETDEWEB)

    Babichenko, V.S.; Kikoin, L.I.; Lazarev, S.D.; Rzhanov, A.E.; Filippov, V.I.

    1984-01-01

    Results of studies on a spatial distribution of defects arising in Ge crystals following ..cap alpha..-particle (40 MeV) irradiation are given. The distribution of defects playing the role of recombination centres is shown to produce the definite effect on diffusion-recombination processes in semiconductors. The carrier capture cross section on recombination centres is determined to be sigma approximately 10/sup -15/ cm/sup -2/. A representation of recombination wall appearing in the vicinity of radiation defect concentration peak is introduced. The experimental data are compared with the developed theoretical representations. It is shown that studies on the photoelectromagnetic effect can give information both on the pattern of radiation defect spatial distribution and recombination parameters of irradiated semiconductors.

  17. The Ly$\\alpha$ emission from high-$z$ galaxies hosting strong Damped Ly$\\alpha$ systems

    CERN Document Server

    Joshi, Ravi; Noterdaeme, Pasquier; Petitjean, Patrick

    2016-01-01

    We study the average Ly$\\alpha$ emission associated with high-$z$ strong (log $N$(H I) $\\ge$ 21) damped Ly$\\alpha$ systems (DLAs). We report Ly$\\alpha$ luminosities ($L_{\\rm Ly\\alpha}$) for the full as well as various sub-samples based on $N$(H I), $z$, $(r-i)$ colours of QSOs and rest equivalent width of Si II$\\lambda$1526 line (i.e., $W_{1526}$). For the full sample, we find $L_{\\rm Ly\\alpha}$$< 10^{41} (3\\sigma)\\ \\rm erg\\ s^{-1}$ with a $2.8\\sigma$ level detection of Ly$\\alpha$ emission in the red part of the DLA trough. The $L_{\\rm Ly\\alpha}$ is found to be higher for systems with higher $W_{1526}$ with its peak, detected at $\\geq 3\\sigma$, redshifted by about 300-400 $\\rm km\\ s^{-1}$ with respect to the systemic absorption redshift, as seen in Lyman Break Galaxies (LBGs) and Ly$\\alpha$ emitters. A clear signature of a double-hump Ly$\\alpha$ profile is seen when we consider $W_{1526} \\ge 0.4$ \\AA\\ and $(r-i) < 0.05$. Based on the known correlation between metallicity and $W_{1526}$, we interpret our...

  18. Effects of the. cap alpha. -adrenoceptor antagonists phentolamine, phenoxybenzamine, and Idazoxan on sympathetic blood flow control in the periodontal ligament of the cat

    Energy Technology Data Exchange (ETDEWEB)

    Edwall, B.; Gazelius, B.

    1988-01-01

    Blood flow changes in the periodontal ligament (PDL) were measured indirectly by monitoring the local clearance of /sup 125/I/sup -/ during electric sympathetic nerve stimulation or close intra-arterial infusions of either noradrenaline (NA) or adrenaline (ADR) before and after administration of phentolamine (PA), phenoxybenzamine (PBZ) or Idazoxan (RX). At the doses used in the present study, PA was the only antagonist that significantly reduced the blood flow decrease seen on activation of sympathetic fibers, although PBZ also reduced this response. Idazoxan, however, did not induce the consistent effect on blood flow decreases seen on sympathetic activation. All three ..cap alpha..-adrenoceptor antagonists almost abolished the effects of exogenously administered NA and ADR. The results suggest the presence of functional post-junctional adrenoceptors of both the ..cap alpha.. 1 and ..cap alpha.. 2 subtypes in the sympathetic regulation of the blood flow in the PDL of the cat. A component of the response elicited by electrical sympathetic stimulation appeared to be resistant to ..cap alpha..-adrenoceptor blockade. Administration of guanethidine (which inhibits further release of NA and neuropeptide Y) after PA abolished this residual sympathetic response. 32 refs.

  19. Development of a radioiodinated ligand for characterising. cap alpha. /sub 1/-adrenoceptors. [Pentolamine and 2 BETA-(4-hydroxyphenyl)-ethylaminomethyl)-tetralone

    Energy Technology Data Exchange (ETDEWEB)

    Adams, A.; Jarrott, B.

    1982-03-15

    Two ..cap alpha..-adrenoceptor antagonists, phentolamine and 2-(..beta..-(4-hydroxyphenyl)-ethylaminomethyl)-tetralone (BE 2254) which are phenolic derivatives were radioiodinated after chloramine-T oxidation of Na/sup 125/I and the labelled material isolated by chromatography. /sup 125/I-Phentolamine does not bind selectively to ..cap alpha..-adrenoceptors in guinea pig brain whereas the /sup 125/I-BE 2254 derivative binds rapidly, reversibly and with high affinity to these receptors with a K/sub d/ of 230 pM. At low concentrations of /sup 125/I-BE 2254 (< 100 pM) approx. 90% of the bound radioligand is specifically bound and under these conditions drug displacement studies show that the ligand binds predominantly to the ..cap alpha../sub 1/ subclass of adrenoceptors. Binding measurements to kidney and smooth muscle membrane preparations indicate that /sup 125/I-BE 2254 may also be a useful tool in the study of ..cap alpha..-adrenoceptors in peripheral tissues. The high specific activity of /sup 125/I-BE 2254 permits the use of minimal quantities of membrane material for receptor assay and ligand displacement measurements, e.g. 250 ..mu..g per assay tube, and this provides a significant advantage over the use of existing radioligands such as /sup 3/H-prazosin which requires approx. 40 times as much tissue.

  20. Radioimmunological determination of 5. cap alpha. -pregnane-3,20-dione in the peripheral venous blood of pregnant women showing pathological estriol values and/or HPL values or gestosis, on the basis of the gestational age. Radioimmunologische Bestimmung des 5. cap alpha. -Pregnan-3,20-dion im peripheren Venenblut schwangerer Frauen einer Gruppe mit pathologischen Oestriol- bzw. HPL-Werten und einer Gestosegruppe in Abhaengigkeit vom Gestationsalter

    Energy Technology Data Exchange (ETDEWEB)

    Klemm-Wolfgramm, E.

    1984-01-01

    A modified method of extraction and radioimmunological determination (iodine-125) is described, designed to monitor the concentrations of 5..cap alpha..-pregnandione (5..cap alpha..-DHP) in patients showing a pathological course of pregnancy and to examine the role of 5..cap alpha..-DHP blood levels in the development of gestosis. In this study, a control group was compared with two patient groups showing either (a) gestosis or (b) reduced levels of estriol and/or HPL. (1) In gestosis, the levels of 5..cap alpha..-DHP showed significant reductions that were proportionate to the degree of the disease, whereas decreases in these hormone levels were only observed to a minor extent in connection with pathological values of estriol and/or HPL. (2) The age of the patient had no influence on the hormone concentrations. (3) The increases in 5..cap alpha..-DHP seen in multiparae were only slight and did not attain any statistical significance. (4) No links were established between the concentrations of HPL and 5..cap alpha..-DHP in the maternal plasma and the development of the fetus. (5) Significantly reduced values of 5..cap alpha..-DHP were determined in mothers showing disorders of fetoplacental function (birth weights between 2500 and 3500 g) or gestosis (birth weights above 3500 g). (6) There were no relationships between the maternal serum levels of estriol, HPL and 5..cap alpha..-DHP and the sex of the fetus. (TRV).

  1. Pre-Equilibrium Alpha-Particle Emission as a Probe to Explore Alpha Clustering in Nuclei

    Science.gov (United States)

    Kravchuk, V. L.; Fotina, O. V.; Gramegna, F.; Bruno, M.; D'Agostino, M.; Sambi, S.; Barlini, S.; Casini, G.

    Experimental data of the double-differential spectra of light particles emitted at pre-equilibrium stage of nuclear processes were obtained at Laboratori Nazionali di Legnaro for the heavy-ion reactions 130 and 250 MeV 16O + 116Sn. Light charged particles were measured in coincidence with evaporation residues in order to avoid unwanted competing mechanisms. The experimental data were collected in a wide angular range from 29 to 82 degrees in the laboratory system. Theoretical model was developed in order to describe simultaneously evaporative and pre-equilibrium emission of the light particles in heavy-ion reactions. Griffin exciton model was used for the description of the pre-equilibrium stage of the compound nucleus formation, while the equilibrium evaporation processes were analyzed in the framework of the statistical theory of heavy-ion reactions. Experimental data were compared with the results of the model calculations and new approach was suggested to take into account alpha cluster formation in the projectile nucleus by measuring and analyzing pre-equilibrium alpha-particle spectra.

  2. Microautoradiographic studies on distribution of 5. cap alpha. -dihydrotestosterone, cyproterone acetate and oestradiol-17. beta. in human prostatic hyperplasia tissue transplanted to juvenile rats

    Energy Technology Data Exchange (ETDEWEB)

    Ruberg, I.; Neumann, F. (Research Laboratory of Schering AG, Berlin West and Bergkamen, FRG); Senge, Th. (Marinenhospital Herne, Clinic of Urology of the Ruhr-University Bochum, FRG)

    1982-01-01

    While maintaining the actual conditions prevailing in benign prostatic hyperplasia (BHP) in man, transplantation of BPH tissue to newborn rats proved a suitable model for examining the distribution of sexual hormones in different tissue compartments of BPH. In combination with the microautoradiographic method, it was possible to demonstrate the residence of the radioactive androgen 5..cap alpha..-=dihydrotestosterone (5..cap alpha..- DHT), the antiandrogen cyproterone acetate (CA) and the oestrogen oestradiol-17..beta..(E/sub 2/) in the epithelium and/or stroma of human BPH tissue. Quantitative evaluation in the form of a point per area count on photographic pictures yielded a silver grain distribution ratio in epithelium and stroma of 1.3:1 and 1.5:1 for epithelium to stroma after administration of (/sup 3/H)5..cap alpha..-DHT and (/sup 3/H)CA administration respectively and 0.5:1 after (/sup 3/H)E/sub 2/. The high tracer recovery rate throughout the stroma following E/sub 2/ administration supports the current view that the stromal proliferation is attributable mainly to oestrogen influences. The relatively high silver particle proportion throughout the stroma following 5..cap alpha..-DHT administration corroborates recent findings which suggest that the exclusive androgen dependency of the glandular epithelium can only be considered in conjunction with an active metabolization of androgens in the stroma. The correspondence in the distribution of the radioactive tracer after (/sup 3/H)5..cap alpha..-DHT and (/sup 3/H)CA administration both in the epithelium and stroma suggests that an antagonism may also exist in the stroma.

  3. Pre-equilibrium {\\alpha}-particle emission as a probe to study {\\alpha}-clustering in nuclei

    CERN Document Server

    Fotina, O V; Eremenko, D O; Platonov, S Yu; Yuminov, O A; Kravchuk, V L; Gramegna, F; Marchi, T; Cinausero, M; D'Agostino, M; Bruno, M; Baiocco, G; Morelli, L; Degerlier, M; Casini, G; Barlini, S; Valdrè, S; Piantelli, S; Pasquali, G; Bracco, A; Camera, F; Wieland, O; Benzoni, G; Blasi, N; Giaz, A; Corsi, A

    2013-01-01

    A theoretical approach was developed to describe secondary particle emission in heavy ion collisions, with special regards to pre-equilibrium {\\alpha}-particle production. Griffin's model of non-equilibrium processes is used to account for the first stage of the compound system formation, while a Monte Carlo statistical approach was used to describe the further decay from a hot source at thermal equilibrium. The probabilities of neutron, proton and {\\alpha}-particle emission have been evaluated for both the equilibrium and pre-equilibrium stages of the process. Fission and {\\gamma}-ray emission competition were also considered after equilibration. Effects due the possible cluster structure of the projectile which has been excited during the collisions have been experimentally evidenced studying the double differential cross sections of p and {\\alpha}-particles emitted in the E=250MeV 16O +116Sn reaction. Calculations within the present model with different clusterization probabilities have been compared to th...

  4. Geocoronal Balmer-alpha Emission Observed by the Wisconsin H-Alpha Mapper During the Southern Sky Survey

    Science.gov (United States)

    Mierkiewicz, E. J.; Haffner, L. M.; Nossal, S. M.; Wilson, M. L.; Freer, C. W.; Babler, B.; Gardner, D.; Roesler, F. L.

    2015-12-01

    After a successful eleven-year run at Kitt Peak Observatory (AZ), the Wisconsin H-Alpha Mapper (WHAM) was moved to Cerro Tololo (Chile) in 2009 to complete the southern portion of the Galactic Balmer-alpha survey. Although WHAM is primarily used for making observations of the interstellar medium, the terrestrial emission present in each of WHAM's astronomical spectra offers a rich resource for studying the Earth's atmosphere. Here we present an overview of the terrestrial Balmer-alpha emission collected during WHAM's first five years of operation under southern skies. Seasonal trends and comparisons with northern hemisphere observations will be discussed. WHAM can detect Balmer-alpha emission as faint as 0.05R in a 30s exposure, covering a 200 km/s (4.4 Angstrom) spectral region with 12 km/s spectral resolution from a 1 degree beam on the sky. With this sensitivity, hundreds of spectra can be collected in a single clear night. Although not capable of fully resolving the geocoronal Balmer-alpha line profile itself, WHAM's sensitivity makes it an exceptional instrument for geocoronal Balmer-alpha intensity observations. This work is supported by NSF award AGS-1352311 and AST-1108911.

  5. Drosophila casein kinase I alpha regulates homolog pairing and genome organization by modulating condensin II subunit Cap-H2 levels.

    Directory of Open Access Journals (Sweden)

    Huy Q Nguyen

    Full Text Available The spatial organization of chromosomes within interphase nuclei is important for gene expression and epigenetic inheritance. Although the extent of physical interaction between chromosomes and their degree of compaction varies during development and between different cell-types, it is unclear how regulation of chromosome interactions and compaction relate to spatial organization of genomes. Drosophila is an excellent model system for studying chromosomal interactions including homolog pairing. Recent work has shown that condensin II governs both interphase chromosome compaction and homolog pairing and condensin II activity is controlled by the turnover of its regulatory subunit Cap-H2. Specifically, Cap-H2 is a target of the SCFSlimb E3 ubiquitin-ligase which down-regulates Cap-H2 in order to maintain homologous chromosome pairing, chromosome length and proper nuclear organization. Here, we identify Casein Kinase I alpha (CK1α as an additional negative-regulator of Cap-H2. CK1α-depletion stabilizes Cap-H2 protein and results in an accumulation of Cap-H2 on chromosomes. Similar to Slimb mutation, CK1α depletion in cultured cells, larval salivary gland, and nurse cells results in several condensin II-dependent phenotypes including dispersal of centromeres, interphase chromosome compaction, and chromosome unpairing. Moreover, CK1α loss-of-function mutations dominantly suppress condensin II mutant phenotypes in vivo. Thus, CK1α facilitates Cap-H2 destruction and modulates nuclear organization by attenuating chromatin localized Cap-H2 protein.

  6. Drosophila Casein Kinase I Alpha Regulates Homolog Pairing and Genome Organization by Modulating Condensin II Subunit Cap-H2 Levels

    Science.gov (United States)

    Nguyen, Huy Q.; Nye, Jonathan; Buster, Daniel W.; Klebba, Joseph E.; Rogers, Gregory C.; Bosco, Giovanni

    2015-01-01

    The spatial organization of chromosomes within interphase nuclei is important for gene expression and epigenetic inheritance. Although the extent of physical interaction between chromosomes and their degree of compaction varies during development and between different cell-types, it is unclear how regulation of chromosome interactions and compaction relate to spatial organization of genomes. Drosophila is an excellent model system for studying chromosomal interactions including homolog pairing. Recent work has shown that condensin II governs both interphase chromosome compaction and homolog pairing and condensin II activity is controlled by the turnover of its regulatory subunit Cap-H2. Specifically, Cap-H2 is a target of the SCFSlimb E3 ubiquitin-ligase which down-regulates Cap-H2 in order to maintain homologous chromosome pairing, chromosome length and proper nuclear organization. Here, we identify Casein Kinase I alpha (CK1α) as an additional negative-regulator of Cap-H2. CK1α-depletion stabilizes Cap-H2 protein and results in an accumulation of Cap-H2 on chromosomes. Similar to Slimb mutation, CK1α depletion in cultured cells, larval salivary gland, and nurse cells results in several condensin II-dependent phenotypes including dispersal of centromeres, interphase chromosome compaction, and chromosome unpairing. Moreover, CK1α loss-of-function mutations dominantly suppress condensin II mutant phenotypes in vivo. Thus, CK1α facilitates Cap-H2 destruction and modulates nuclear organization by attenuating chromatin localized Cap-H2 protein. PMID:25723539

  7. User response and equity considerations regarding emission cap-and-trade schemes for travel

    Energy Technology Data Exchange (ETDEWEB)

    Perrels, A. [Government Institute for Economic Research VATT, Helsinki (Finland)

    2010-05-15

    In most countries with greenhouse gas emission reduction commitments, transportation has been relatively spared, thus, far in the targeting of reduction obligations, owing to the supposedly high marginal cost. With the prospect of tightening reduction targets, pressure is, however, mounting to address transportation more seriously in the near term and not to rely solely on medium to long-term breakthroughs of alternative fuel technologies. This means stricter policies at the demand side of the mobility market. In addition to fiscal and spatial policies, cap-and-trade systems have been put forward as a new option that deserves serious consideration. This paper reviews the possibilities and pitfalls of such a system applied to passenger transport. Key concerns are the transaction costs of the system and trade-offs between transaction cost and equity effects. A simple system with low(er) transaction cost is more likely to invoke politically sensitive equity effects. On the basis of the recent upsurge in monitoring and feedback studies, one may also conclude that the organisation and tailoring of the information interfaces for the household/traveller requires still elaborate study and testing.

  8. Exploring clustering in alpha-conjugate nuclei using the thick target inverse kinematic technique for multiple alpha emission

    Science.gov (United States)

    Barbui, M.; Hagel, K.; Gauthier, J.; Wuenschel, S.; Goldberg, V. Z.; Zheng, H.; Giuliani, G.; Rapisarda, G.; Kim, E.-J.; Liu, X.; Natowitz, J. B.; Desouza, R. T.; Hudan, S.; Fang, D.

    2015-10-01

    Searching for alpha cluster states analogous to the 12C Hoyle state in heavier alpha-conjugate nuclei can provide tests of the existence of alpha condensates in nuclear matter. Such states are predicted for 16O, 20Ne, 24Mg, etc. at excitation energies slightly above the decay threshold. The Thick Target Inverse Kinematics (TTIK) technique can be successfully used to study the breakup of excited self-conjugate nuclei into many alpha particles. The reaction 20Ne + α at 11 and 13 AMeV was studied at Cyclotron Institute at Texas A&M University. Here the TTIK method was used to study both single α-particle emission and multiple α-particle decays. Due to the limited statistics, only events with alpha multiplicity up to three were analyzed. The analysis of the three α-particle emission data allowed the identification of the Hoyle state and other 12C excited states decaying into three alpha particles. The results will be shown and compared with other data available in the literature. Another experiment is planned in August 2015 to study the system 28Si + α at 15 AMeV. Preliminary results will be shown. Supported by the U.S. DOE and the Robert A. Welch Foundation, Grant No. A0330.

  9. Association of elongation factor 1 alpha and ribosomal protein L3 with the proline-rich region of yeast adenylyl cyclase-associated protein CAP.

    Science.gov (United States)

    Yanagihara, C; Shinkai, M; Kariya, K; Yamawaki-Kataoka, Y; Hu, C D; Masuda, T; Kataoka, T

    1997-03-17

    CAP is a multifunctional protein; the N-terminal region binds adenylyl cyclase and controls its response to Ras while the C-terminal region is involved in cytoskeletal regulation. In between the two regions, CAP possesses two proline-rich segments, P1 and P2, resembling a consensus sequence for binding SH3 domains. We have identified two yeast proteins with molecular sizes of 48 and 46 kDa associated specifically with P2. Determination of partial protein sequences demonstrated that the 48-kDa and 46-kDa proteins correspond to EF1 alpha and rL3, respectively, neither of which contains any SH3-domain-like sequence. Deletion of P2 from CAP resulted in loss of the activity to bind the two proteins either in vivo or in vitro. Yeast cells whose chromosomal CAP was replaced by the P2-deletion mutant displayed an abnormal phenotype represented by dissociated localizations of CAP and F-actin, which were colocalized in wild-type cells. These results suggest that these associations may have functional significance.

  10. Alpha-emission channeling investigations of the lattice location of Li in Ge

    NARCIS (Netherlands)

    Wahl, U; Jahn, SG; Restle, M; Ronning, C; Quintel, H; BharuthRam, K; Hofsass, H

    1996-01-01

    The alpha-emission channeling and blocking technique is a direct method for lattice site determination of radioactive atoms in single crystals. Position-sensitive detection of emitted alpha-particles provides an efficient means of carrying out such experiments at very low doses (10(10)-10(11) cm(-2)

  11. Lyman alpha emission from the first galaxies : Implications of UV backgrounds and the formation of molecules

    NARCIS (Netherlands)

    Latif, M. A.; Schleicher, D. R. G.; Spaans, Maarten; Zaroubi, S.

    2011-01-01

    The Lyman alpha line is a robust tracer of high redshift galaxies. We present estimates of Lyman alpha emission from a protogalactic halo illuminated by UV background radiation fields with various intensities. For this purpose, we performed cosmological hydrodynamics simulations with the adaptive me

  12. Internode length in Pisum. Gene na may block gibberellin synthesis between ent-7. cap alpha. -hydroxykaurenoic acid and biggerellin A/sub 12/-aldehyde. [Pisum sativum

    Energy Technology Data Exchange (ETDEWEB)

    Ingram, T.J.; Reid, J.B.

    1987-04-01

    The elongation response of the gibberellin (GA) deficient genotypes na, ls, and lh of peas (Pisum sativum L.) to a range of GA-precursors was examined. Plants possessing gene na did not respond to precursors in the GA biosynthetic pathway prior to GA/sub 12/-aldehyde. In contrast, plants possessing lh and ls responded as well as wild-type plants (dwarfed with AMO-1618) to these compounds. The results suggest that GA biosynthesis is blocked prior to ent-kaurene in the lh and ls mutants and between ent-7..cap alpha..-hydroxykaurenoic acid and GA/sub 12/-aldehyde in the na mutant. Feeds of ent(/sup 3/H)kaurenoic acid and (/sup 2/H)GA/sub 12/-aldehyde to a range of genotypes supported the above conclusions. The na line WL1766 was shown by gas chromatography-mass spectrometry (GC-MS) to metabolize(/sup 2/H)GA/sub 12/-aldehyde to a number of (/sup 2/H)C/sub 19/-GAs including GA/sub 1/. However, there was no indication in na genotypes for the metabolism of ent-(/sup 3/H)kaurenoic acid to these GAs. In contrast, the expanding shoot tissue of all Na genotypes examined metabolized ent-(/sup 3/H)kaurenoic acid to radioactive compounds that co-chromatographed with GA/sub 1/, GA/sub 8/, GA/sub 20/, and GA/sub 29/. However, insufficient material was present for unequivocal identification of the metabolites. The radioactive profiles from HPLC of extracts of the node treated with ent-(/sup 3/H)kaurenoic acid were similar for both Na and na plants and contained ent-16..cap alpha..,17-dihydroxykaurenoic acid and ent-6..cap alpha..,7..cap alpha..,16..beta..,17-tetrahydroxykaurenoic acid (both characterized by GC-MS), suggesting that the metabolites arose from side branches of the main GA-biosynthetic pathway. Thus, both Na and na plants appear capable of ent-7..cap alpha..-hydroxylation.

  13. Isolation and characterization of cDNA encoding the alpha subunit of Cap Z(36/32), an actin-capping protein from the Z line of skeletal muscle.

    OpenAIRE

    Casella, J F; Casella, S J; Hollands, J. A.; Caldwell, J E; Cooper, J A

    1989-01-01

    cDNA encoding the alpha chain of Cap Z has been isolated by screening a lambda gt11 library with affinity-purified antibodies. A single cDNA insert (designated CE2) of 2153 base pairs (bp) contains an open reading frame of 836 bp, which is incomplete at its 5' end. The technique of "rapid amplification of cDNA ends" has been used to extend the 5' end of this open reading frame to a potential transcription initiation site that is preceded by 320 bp of an apparently untranslated region. The pro...

  14. {alpha}-particle emission probabilities in the decay of {sup 235}U

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Torano, Eduardo [Laboratorio de Metrologia de Radiaciones Ionizantes, CIEMAT, Madrid (Spain)]. E-mail: E.Garciatorano@ciemat.es; Teresa Crespo, M. [Laboratorio de Metrologia de Radiaciones Ionizantes, CIEMAT, Madrid (Spain); Roteta, Miguel [Laboratorio de Metrologia de Radiaciones Ionizantes, CIEMAT, Madrid (Spain); Sibbens, Goedele [European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (Belgium); Pomme, Stefaan [European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (Belgium); Martin Sanchez, Alejandro [Departamento de Fisica, Universidad de Extremadura, Badajoz (Spain); Pilar Rubio Montero, M. [Departamento de Fisica, Universidad de Extremadura, Badajoz (Spain); Woods, Simon [Radioactivity Metrology Group, National Physical Laboratory, Teddington, Middlesex (United Kingdom); Pearce, Andy [Radioactivity Metrology Group, National Physical Laboratory, Teddington, Middlesex (United Kingdom)

    2005-09-21

    {sup 235}U decays by {alpha}-particle emission to {sup 231}Th. The decay scheme of this nuclide is very complex, with more than 20 alpha branches. Recommended values for P {sub {alpha}} of this nuclide are based on measurements carried out in 1975. This work presents the results of new measurements made with Si detectors and sources of enriched uranium in the frame of the EUROMET 591 cooperation project. The use of improved measurement techniques and numerical analysis of spectra allowed a new set of P {sub {alpha}} values for 13 lines with improved uncertainties to be obtained.

  15. Hubble Space Telescope Imaging of Lyman Alpha Emission at z=4.4

    CERN Document Server

    Finkelstein, Steven L; Windhorst, Rogier A; Ryan, Russell E; Hathi, Nimish P; Finkelstein, Keely D; Anderson, Jay; Grogin, Norman A; Koekemoer, Anton M; Malhotra, Sangeeta; Mutchler, Max; Rhoads, James E; McCarthy, Patrick J; O'Connell, Robert W; Balick, Bruce; Bond, Howard E; Calzetti, Daniela; Disney, Michael J; Dopita, Michael A; Frogel, Jay A; Hall, Donald N B; Holtzman, Jon A; Kimble, Randy A; Luppino, Gerard; Paresce, Francesco; Saha, Abhijit; Silk, Joseph I; Trauger, John T; Walker, Alistair R; Whitmore, Bradley C; Young, Erick T

    2010-01-01

    We present the highest redshift detections of resolved Lyman alpha emission, using Hubble Space Telescope/ACS F658N narrowband-imaging data taken in parallel with the Wide Field Camera 3 Early Release Science program in the GOODS CDF-S. We detect Lyman alpha emission from three spectroscopically confirmed z = 4.4 Lyman alpha emitting galaxies (LAEs), more than doubling the sample of LAEs with resolved Lyman alpha emission. Comparing the light distribution between the rest-frame ultraviolet continuum and narrowband images, we investigate the escape of Lyman alpha photons at high redshift. While our data do not support a positional offset between the Lyman alpha and rest-frame ultraviolet (UV) continuum emission, the half-light radii in two out of the three galaxies are significantly larger in Lyman alpha than in the rest-frame UV continuum. This result is confirmed when comparing object sizes in a stack of all objects in both bands. Additionally, the narrowband flux detected with HST is significantly less than...

  16. 1. cap alpha. ,25-Dihydroxyvitamin D/sub 3/ inhibits. gamma. -interferon synthesis by normal human peripheral blood lymphocytes

    Energy Technology Data Exchange (ETDEWEB)

    Reichel, H.; Koeffler, H.P.; Tobler, A.; Norman, A.W.

    1987-05-01

    1..cap alpha..,25-Dihydroxyvitamin D/sub 3/ (1,25-(OH)/sub 2/D/sub 3/), the biologically active metabolite of vitamin D/sub 3/, inhibited synthesis of ..gamma..-interferon (IFN-..gamma..) by phytohemagglutinin-activated peripheral blood lymphocytes (PBLs). A significant reduction of IFN-..gamma.. protein levels in PBL culture medium was achieved with a physiologic 1,25-(OH)/sub 2/D/sub 3/ concentration, 1,25-(OH)/sub 2/D/sub 3/ also inhibited accumulation of IFN-..gamma.. mRNA in activated PBLs in a dose-dependent fashion. The ability of 1,25-(OH)/sub 2/D/sub 3/ to modulate IFN-..gamma.. protein synthesis was unaltered in the presence of high concentrations of recombinant human interleukin 2. The suppression of IFN-..gamma.. synthesis by PBLs was specific for 1,25-(OH)/sub 2/D/sub 3/; the potencies of other vitamin D/sub 3/ metabolites were correlated with their affinities for the cellular 1,25-(OH)/sub 2/D/sub 3/ receptor. The time course of 1,25-(OH)/sub 2/D/sub 3/ receptor expression in phytohemagglutinin-activated PBLs was correlated with the time course of 1,25-(OH)/sub 2/D/sub 3/-mediated inhibition of IFN-..gamma.. synthesis. Finally, the authors examined the effects of 1,25-(OH)/sub 2/D/sub 3/ on the constitutive IFN-..gamma.. production by two human T-lymphocyte lines transformed by human T-lymphotropic virus type I. The cell lines were established from a normal donor (cell line S-LB1) and from a patient with vitamin D-dependent rickets type 2 (cell line Ab-VDR). IFN-..gamma.. synthesis by S-LB1 cells was inhibited in a dose-dependent fashion by 1,25-(OH)/sub 2/D/sub 3/, whereas IFN-..gamma.. synthesis by Ab-VDR cells was not altered by 1,25-(OH)/sub 2/D/sub 3/. The data presented in this study provide evidence for a role of 1,25-(OH)/sub 2/D/sub 3/ in immunoregulation.

  17. Structure-function relationships in the Na,K-ATPase. cap alpha. subunit: site-directed mutagenesis of glutamine-111 to arginine and asparagine-122 to aspartic acid generates a ouabain-resistant enzyme

    Energy Technology Data Exchange (ETDEWEB)

    Price, E.M.; Lingrel, J.B.

    1988-11-01

    Na,K-ATPases from various species differ greatly in their sensitivity to cardiac glycosides such as ouabain. The sheep and human enzymes are a thousand times more sensitive than the corresponding ones from rat and mouse. To define the region of the ..cap alpha..1 subunit responsible for this differential sensitivity, chimeric cDNAs of sheep and rat were constructed and expressed in ouabain-sensitive HeLa cells. The construct containing the amino-terminal half of the rat ..cap alpha..1 subunit coding region and carboxyl-terminal half of the sheep conferred the ouabain-resistant phenotype to HeLa cells while the reverse construct did not. This indicates that the determinants involved in ouabain sensitivity are located in the amino-terminal half of the Na,K-ATPase ..cap alpha.. subunit. By use of site-directed mutagenesis, the amino acid sequence of the first extracellular domain (H1-H2) of the sheep ..cap alpha..1 subunit was changed to that of the rat. When expressed in HeLa cells, this mutated sheep ..cap alpha..1 construct, like the rat/sheep chimera, was able to confer ouabain resistance to these cells. Furthermore, similar results were observed when HeLa cells were transfected with a sheep ..cap alpha..1 cDNA containing only two amino acid substitutions. The resistant cells, whether transfected with the rat ..cap alpha..1 cDNA, the rat/sheep chimera, or the mutant sheep ..cap alpha..1 cDNAs, exhibited identical biochemical characteristics including ouabain-inhibitable cell growth, /sup 86/Rb/sup +/ uptake, and Na,K-ATPase activity. These results demonstrate that the presence of arginine and aspartic acid on the amino end and carboxyl end, respectively, of the H1-H2 extracellular domain of the Na,K-ATPase ..cap alpha.. subunit together is responsible for the ouabain-resistant character of the rat enzyme and the corresponding residues in the sheep ..cap alpha..1 subunit (glutamine and asparagine) are somehow involved in ouabain binding.

  18. Ly$\\alpha$ emission from Green Peas: the role of circumgalactic gas density, covering, and kinematics

    CERN Document Server

    Henry, Alaina; Martin, Crystal; Erb, Dawn

    2015-01-01

    We report Hubble Space Telescope/Cosmic Origins Spectrograph observations of the Ly$\\alpha$ emission and interstellar absorption lines in a sample of ten star-forming galaxies at z~0.2. Selected on the basis of high equivalent width optical emission lines, the sample, dubbed "Green Peas," make some of the best analogs for young galaxies in an early Universe. We detect Ly$\\alpha$ emission in all ten galaxies, and 9/10 show double-peaked line profiles suggestive of low H I column density. We measure Ly$\\alpha$/H$\\alpha$ flux ratios of 0.5-5.6, implying that 5% to 60% of Ly$\\alpha$ photons escape the galaxies. These data confirm previous findings that low-ionization metal absorption (LIS) lines are weaker when Ly$\\alpha$ escape fraction and equivalent width are higher. However, contrary to previously favored interpretations of this trend, increased Ly$\\alpha$ output cannot be the result of a varying H I covering: the Lyman absorption lines (Ly$\\beta$ and higher) show a covering fraction near unity for gas with N...

  19. A z ~ 5.7 Ly{\\alpha} Emission Line with an Ultra Broad Red Wing

    CERN Document Server

    Yang, Huan; Zheng, Zhen-Ya; Malhotra, Sangeeta; Rhoads, James E; Infante, Leopoldo

    2014-01-01

    Using Ly{\\alpha} emission line as a tracer of high redshift star forming galaxies, hundreds of Ly{\\alpha} emission line galaxies (LAEs) at z > 5 have been detected. These LAEs are considered to be low mass young galaxies, critical to the reionization of the universe and the metal enrichment of circumgalactic medium (CGM) and intergalactic medium (IGM). It is assumed that outflows in LAEs can help ionizing photons and Ly{\\alpha} photons escape out of galaxies. However we still know little about the outflows in high redshifts LAEs due to observational difficulties, especially at redshift > 5. Models of Ly{\\alpha} radiative transfer predict asymmetric Ly{\\alpha} line profiles with broad red wing in LAEs with outflows. Here we report a z ~ 5.7 Ly{\\alpha} emission line with a broad red wing extending to > 1000 km/s relative to the peak of Ly{\\alpha} line, which has been detected in only a couple of z > 5 LAEs till now. If the broad red wing is ascribed to gas outflow instead of AGN activity, the outflow velocity c...

  20. The Temporal Behaviour of Lyman-alpha Emission During Solar Flares From SDO/EVE

    CERN Document Server

    Milligan, Ryan O

    2015-01-01

    Despite being the most prominent emission line in the solar spectrum, there has been a notable lack of studies devoted to variations in Lyman-alpha (Ly$\\alpha$) emission during solar flares in recent years. The few examples that do exist, however, have shown Ly$\\alpha$ emission to be a substantial radiator of the total energy budget of solar flares (on the order of 10%). It is also a known driver of fluctuations in earth's ionosphere. The EUV Variability Experiment (EVE) onboard the Solar Dynamics Observatory now provides broadband, photometric Ly$\\alpha$ data at 10 s cadence, and has observed scores of solar flares in the 5 years since it was launched. However, the time profiles appear to display a rise time of tens of minutes around the time of the flare onset. This is in stark contrast to the rapid, impulsive increase observed in other intrinsically chromospheric features (H$\\alpha$, Ly$\\beta$, LyC, C III, etc.). Furthermore, the Ly$\\alpha$ emission peaks around the time of the peak of thermal soft X-ray e...

  1. The Gaia-ESO Survey: Catalogue of H$\\alpha$ emission stars

    CERN Document Server

    Traven, Gregor; Van Eck, Sophie; Klutsch, Alexis; Bonito, Rosaria; Lanzafame, Alessandro C; Alfaro, Emilio J; Bayo, Amelia; Bragaglia, Angela; Costado, María Teresa; Damiani, Francesco; Flaccomio, Ettore; Frasca, Antonio; Hourihane, Anna; Jimenez-Esteban, Fran; Lardo, Carmela; Morbidelli, Lorenzo; Pancino, Elena; Prisinzano, Loredana; Sacco, Germano G; Worley, Clare C

    2015-01-01

    We discuss the properties of H$\\alpha$ emission stars across the sample of 22035 spectra from the Gaia-ESO Survey internal data release, observed with the GIRAFFE instrument and largely belonging to stars in young open clusters. Automated fits using two independent Gaussian profiles and a third component that accounts for the nebular emission allow us to discern distinct morphological types of H$\\alpha$ line profiles with the introduction of a simplified classification scheme. All in all we find 3765 stars with intrinsic emission and sort their spectra into eight distinct morphological categories: single--component emission, emission blend, sharp emission peaks, double emission, P-Cygni, inverted P-Cygni, self--absorption, and emission in absorption. We have more than one observation for 1430 stars in our sample, thus allowing a quantitative discussion of the degree of variability of H$\\alpha$ emission profiles, which is expected for young, active objects. We present a catalogue of stars with properties of th...

  2. Biochemical studies of mouse brain tubulin: colchicine binding (DEAE-cellulose filter) assay and subunits (. cap alpha. and. beta. ) biosynthesis and degradation (in newborn brain)

    Energy Technology Data Exchange (ETDEWEB)

    Tse, Cek-Fyne

    1978-01-01

    A DEAE-cellulose filter assay, measuring (/sup 3/H)colchicine bound to colchicine binding protein (CBP) absorbed on filter discs, has been modified to include lM sucrose in the incubation medium for complexing colchicine to CBP in samples before applying the samples to filter discs (single point assay). Due to the much greater stability of colchicine binding capacity in the presence of lM sucrose, multiple time-point assays and least squares linear regression analysis were not necessary for accurate determination of CBP in hybrid mouse brain at different stages of development. The highest concentrations of CBP were observed in the 160,000g supernatant and pellet of newborn brain homogenate. Further studies of the modified filter assay documented that the assay has an overall counting efficiency of 27.3%, that DEAE-cellulose filters bind and retain all tubulin in the assay samples, and that one molecule of colchicine binds approximately one molecule of tubulin dimer. Therefore, millimoles of colchicine bound per milligram total protein can be used to calculate tubulin content. With this technique tubulin content of brain supernatant was found to be 11.9% for newborn, and 7.15% for 11 month old mice. Quantitative densitometry was also used to measure mouse brain supernatant actin content for these two stages. In vivo synthesis and degradation rates of tubulin ..cap alpha.. and ..beta.. subunits of two day mouse brain 100,000g supernatant were studied after intracerebral injection of (/sup 3/H)leucine. Quantitative changes of the ratio of tritium specific activities of tubulin ..cap alpha.. and ..beta.. subunits with time were determined. The pattern of change was biphasic. During the first phase the ratio decreased; during the second phase the ratio increased continuously. An interpretation consistent with all the data in this study is that the ..cap alpha.. subunit is synthesized at a more rapid rate than the ..beta.. subunit. (ERB)

  3. Presynaptic. cap alpha. -adrenoceptors and opiate receptors: inhibition of (/sup 3/H)noradrenaline release from rat cerebral cortex slices by different mechanisms

    Energy Technology Data Exchange (ETDEWEB)

    Schoffelmeer, A.N.M.; Mulder, A.H. (Vrije Univ., Amsterdam (Netherlands))

    1982-04-23

    The inhibitory effects of morphine and Cd/sup 2 +/ on electrically evoked (/sup 3/H)noradrenaline release from superfused brain slices were unaffected when release was enhanced by increasing the pulse duration, while the inhibitory effect of noradrenaline and the enhancing effect of phentolamine were diminished. A similar enhancement of (/sup 3/H)noradrenaline release by 4-aminopyridine reduced the modulatory effects of all drugs examined. Therefore there seem to be different mechanisms for the effect of presynaptic ..cap alpha..-adrenoceptors and opiate receptors on the availability of Ca/sup 2 +/ for the stimulus-secretion coupling process in noradrenergic nerve terminals.

  4. Cross sections for the /sup 14/N(n,p/sub 0/), (n,. cap alpha. /sub 0/), and (n,. cap alpha. /sub 1/) reactions from 0. 5 to 15 MeV. [0. 5 to 15 MeV, tables, diagrams

    Energy Technology Data Exchange (ETDEWEB)

    Morgan, G.L.

    1978-11-01

    Cross sections were measured for the /sup 14/N(n,p/sub 0/) reaction from 0.5 to 7.0 MeV and for the (n,..cap alpha../sub 0/) and (n,..cap alpha../sub 1/) reactions from 1 to 15 MeV and 4 to 15 MeV, respectively. The data were obtained using a gaseous scintillator containing N/sub 2/ and Xe mixtures. A linac was used as a pulsed, white neutron source with a 29-m flight path. The results of the measurement are compared to the current evaluated file for nitrogen; agreement is good for neutron energies below 8 MeV, but the measurement is substantially higher than the evaluation for neutron energies near 10 MeV. 28 references.

  5. Discovery of a very cool object with extraordinarily strong H(alpha) emission

    CERN Document Server

    Barrado y Navascués, D; Martín, E L; Béjar, V J S; Rebolo, R; Mundt, R; Navascues, David Barrado y; Osorio, Maria Rosa Zapatero; Martin, Eduardo L.; Bejar, Victor J.S.; Rebolo, Rafael; Mundt, Reinhard

    2002-01-01

    We report on the finding of the strongest H(alpha) emission -pseudoequivalent width of 705 Angstrom- known so far in a young, late type dwarf. This object, named as SOri71, is a substellar candidate member of the 1-8 Myr star cluster sigma Orionis. Due to its overluminous location in color-magnitude diagrams, SOri71 might be younger than other cluster members, or a binary of similar components. Its mass is in the range 0.021-0.012 M(sun), depending on evolutionary models and possible binarity. The broad H(alpha) line of SOri71 appears asymmetric, indicative of high velocity mass motions in the H(alpha) forming region. The origin of this emission is unclear at the present time. We discuss three possible scenarios: accretion from a disk, mass exchange between the components of a binary system, and emission from a chromosphere.

  6. A Deep Narrowband Imaging Search for CIV and He II Emission from Ly$\\alpha$ Blobs

    CERN Document Server

    Battaia, Fabrizio Arrigoni; Hennawi, Joseph F; Prochaska, J Xavier; Matsuda, Yuichi; Yamada, Toru; Hayashino, Tomoki

    2014-01-01

    We conduct a deep narrow-band imaging survey of 13 Ly$\\alpha$ blobs (LABs) located in the SSA22 proto-cluster at z~3.1 in the CIV and HeII emission lines in an effort to constrain the physical process powering the Ly$\\alpha$ emission in LABs. Our observations probe down to unprecedented surface brightness limits of 2.1 $-$ 3.4 $\\times$ 10$^{-18}$ erg s$^{-1}$ cm$^{-2}$ arcsec$^{-2}$ per 1 arcsec$^2$ aperture (5$\\sigma$) for the HeII$\\lambda$1640 and CIV$\\lambda$1549 lines, respectively. We do not detect extended HeII and CIV emission in any of the LABs, placing strong upper limits on the HeII/Ly$\\alpha$ and CIV/Ly$\\alpha$ line ratios, of 0.11 and 0.16, for the brightest two LABs in the field. We conduct detailed photoionization modeling of the expected line ratios and find that, although our data constitute the deepest ever observations of these lines, they are still not deep enough to rule out a scenario where the Ly$\\alpha$ emission is powered by the ionizing luminosity of an obscured AGN. Our models can ac...

  7. Large-scale clustering of Lyman-alpha emission intensity from SDSS/BOSS

    CERN Document Server

    Croft, Rupert A C; Zheng, Zheng; Bolton, Adam; Dawson, Kyle S; Peterson, Jeffrey B; York, Donald G; Eisenstein, Daniel; Brinkmann, Jon; Brownstein, Joel; Delubac, Timothée; Font-Ribera, Andreu; Hamilton, Jean-Christophe; Lee, Khee-Gan; Myers, Adam; Palanque-Delabrouille, Nathalie; Pâris, Isabelle; Petitjean, Patrick; Pieri, Matthew M; Ross, Nicholas P; Rossi, Graziano; Schlegel, David J; Schneider, Donald P; Slosar, Anže; Vazquez, José; Viel, Matteo; Weinberg, David H; Yèche, Christophe

    2015-01-01

    (Abridged) We detect the large-scale structure of Lya emission in the Universe at redshifts z=2-3.5 by measuring the cross-correlation of Lya surface brightness with quasars in SDSS/BOSS. We use a million spectra targeting Luminous Red Galaxies at z, the amplitude of mass fluctuations, and the quasar and Lya emission bias factors. Using known values, we infer (b_alpha/3) = (3.9 +/- 0.9) x 10^-21 erg/s cm^-2 A^-1 arcsec^-2, where b_alpha is the Lya emission bias factor. If the dominant sources of Lya emission are star forming galaxies, we infer rho_SFR = (0.28 +/- 0.07) (3/b_alpha) /yr/Mpc^3 at z=2-3.5. For b_alpha=3, this value is a factor of 21-35 above previous estimates from individually detected Lya emitters, although consistent with the total rho_SFR derived from dust-corrected, continuum UV surveys. 97% of the Lya emission in the Universe at these redshifts is therefore undetected in previous surveys of Lya emitters. Our measurement is much greater than seen from stacking analyses of faint halos surroun...

  8. Broad Ly alpha Emission from Three Nearby BL Lacertae Objects

    CERN Document Server

    Stocke, John T; Perlman, Eric S

    2011-01-01

    We present far-UV HST/COS spectra of four nearby BL Lac Objects. BL Lac spectra are dominated by a smooth, power-law continuum which arises in a relativistic jet. However, the spectra are not necessarily featureless; weak, broad- and/or narrow-line emission is sometimes seen in high-quality optical spectra. We present detections of Lya emission in HST/COS spectra of Mrk421 (z=0.030) and PKS2005-489 (z=0.071) as well as an archival HST/GHRS observation of Mrk501 (z=0.0337). Archival HST/STIS observations of PKS2155-304 (z=0.116) show no Lya emission to a very low upper limit. Using the assumption that the broad-line region (BLR) clouds are asymmetrically placed around the AGN, we use these measured Lya emission features to constrain either the relativistic Gamma values for the ionizing continuum produced by the jet (in the ionization-bounded case) or the mass of warm gas (in the density-bounded case). While realistic Gamma values can be obtained for all four cases, the values for Mrk421 and PKS2155-304 are hig...

  9. /sup 45/Ca efflux for myometrial cells: comparison of the effects of prostaglandin F/sub 2/. cap alpha. (PGF/sub 2/), oxytocin (OT) and arachidonate (A)

    Energy Technology Data Exchange (ETDEWEB)

    Katona, G.; Molnar, M.; Toth, M.; Hertelendy, F.

    1986-03-01

    The aim of this study was to measure PGF/sub 2..cap alpha../-induced Ca/sup 2 +/ release from uterine cells and to compare this to the actions of OT and A. Smooth muscle cells isolated from the uterus (shell gland) of laying hens were cultured for 7 days in M199 plus 10% fetal calf serum. The cells were treated with digitonin (20..mu..M) and preloaded with /sup 45/Ca for 40 min. Addition of PGF/sub 2..cap alpha../ caused a biphasic /sup 45/Ca-efflux. There was a small but significant /sup 45/Ca-release within 30 sec (rapid phase) followed by a larger one within 7 min (slow phase). In comparison, both OT and A stimulated /sup 45/Ca efflux during a single, slow phase. The maximal effect of A was observed at < 7 min, whereas that of OT was slower, peaking after 7 min. Mepacrin, an inhibitor of A release, attenuated the action of OT without having any effect on A promoted /sup 45/Ca-efflux. Indomethacin, an inhibitor of PG synthase, failed to suppress the Ca-releasing effect of A suggesting the A itself or a lipoxygenase product may have been responsible for the observed effects. Moreover, these results provide suggestive evidence that A release is an important step in the action of various uterotonic agents converging on the mobilization of intracellular Ca.

  10. Alpha-particle emission probabilities in the decay of {sup 240}Pu

    Energy Technology Data Exchange (ETDEWEB)

    Sibbens, G., E-mail: goedele.sibbens@ec.europa.e [European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Retieseweg 111, B-2440 Geel (Belgium); Pomme, S.; Altzitzoglou, T. [European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Retieseweg 111, B-2440 Geel (Belgium); Garcia-Torano, E. [Laboratorio de Metrologia de Radiaciones Ionizantes, CIEMAT, Avda. Complutense 22, 28040 Madrid (Spain); Janssen, H.; Dersch, R.; Ott, O. [Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig (Germany); Martin Sanchez, A. [Departamento de Fisica, Universidad de Extremadura, Badajoz, E-06071 (Spain); Rubio Montero, M.P. [Departamento de Fisica Aplicada, Universidad de Extremadura, Merida, Badajoz, E-06800 (Spain); Loidl, M. [Laboratoire National Henri Becquerel, LNE/CEA-LIST, 91191 Gif-sur-Yvette (France); Coron, N.; Marcillac, P. de [Institut d' Astrophysique Spatiale, CNRS, 91405 Orsay Campus (France); Semkow, T.M. [Wadsworth Center, New York State Department of Health, Albany, NY 12201 (United States)

    2010-07-15

    Sources of enriched {sup 240}Pu were prepared by vacuum evaporation on quartz substrates. High-resolution alpha-particle spectrometry of {sup 240}Pu was performed with high statistical accuracy using silicon detectors and with low statistical accuracy using a bolometer. The alpha-particle emission probabilities of six transitions were derived from the spectra and compared with literature values. Additionally, some alpha-particle emission probabilities were derived from {gamma}-ray intensity measurements with a high-purity germanium detector. The alpha-particle emission probabilities of the three main transitions at 5168.1, 5123.6 and 5021.2 keV were derived from seven aggregate spectra analysed with five different fit functions and the results were compatible with evaluated data. Two additional weak peaks at 4863.5 and 4492.0 keV were fitted separately, using the exponential of a polynomial function to represent the underlying tailing of the larger peaks. The peak at 4655 keV could not be detected by alpha-particle spectrometry, while {gamma}-ray spectrometry confirms that its intensity is much lower than expected from literature.

  11. SO2 emission cap planning for Chengdu-Chongqing economic zone

    Institute of Scientific and Technical Information of China (English)

    Peng Yi; Ning Duan; Fare Chai; Yaxuan Xu; Youjiang He

    2012-01-01

    The SO2 emission sources of the Chengdu-Chongqing economic zone were divided into 556 emissions units according to four different categories,which are city,industry,point sources,and area sources.The CALPUFF model was used to calculate the contribution of each unit,and consequently obtain an influence-transferring matrix.To ensure that the SO2 concentrations of 46 cities and counties in the Chengdu-Chongqing economic zone meet air quality standards,an emission optimization model was developed to calculate optimal emissions of each emission unit under different development scenarios.The result showed the optimal emissions of SO2 by different provinces and industries.To achieve the target of restricting and optimizing development,corresponding planning programs were developed for every district.

  12. Bremsstrahlung emission probability in the {alpha} decay of {sup 210}Po

    Energy Technology Data Exchange (ETDEWEB)

    Boie, Hans-Hermann

    2009-06-03

    A high-statistics measurement of bremsstrahlung emitted in the {alpha} decay of {sup 210}Po has been performed. The measured differential emission probabilities, which could be followed up to {gamma}-energies of {proportional_to} 500 keV, allow for the first time for a serious test of various model calculations of the bremsstrahlung accompanied {alpha} decay. It is shown that corrections to the {alpha}-{gamma} angular correlation due to the interference between the electric dipole and quadrupole amplitudes and due to the relativistic character of the process have to be taken into account. With the experimentally derived angular correlation the measured energydifferential bremsstrahlung emission probabilities show excellent agreement with the fully quantum mechanical calculation. (orig.)

  13. Two source emission behaviour of alpha fragments of projectile having energy around 1 GeV per nucleon

    CERN Document Server

    Singh, V; Pathak, Ramji

    2010-01-01

    The emission of projectile fragments alpha has been studied in ^{84}Kr interactions with nuclei of the nuclear emulsion detector composition at relativistic energy below 2 GeV per nucleon. The angular distribution of projectile fragments alpha in terms of transverse momentum could not be explained by a straight and clean-cut collision geometry hypothesis of Participant - Spectator (PS) Model. Therefore, it is assumed that projectile fragments alpha were produced from two separate sources that belong to the projectile spectator region differing drastically in their temperatures. It has been clearly observed that the emission of projectile fragments alpha are from two different sources. The contribution of projectile fragments alpha from contact layer or hot source is a few percent of the total emission of projectile fragments alphas. Most of the projectile fragments alphas are emitted from the cold source. It has been noticed that the temperature of hot and cold regions are dependent on the projectile mass num...

  14. Aqueous based synthesis of N-acetyl-L-cysteine capped ZnSe nanocrystals with intense blue emission

    Science.gov (United States)

    Soheyli, Ehsan; Sahraei, Reza; Nabiyouni, Gholamreza

    2016-10-01

    In this work a very simple reflux route for preparation of ZnSe nanocrystals with minor modification and faster preparation over conventional ones is introduced. X-ray diffraction analysis indicated that the ZnSe nanocrystals have a cubic structure. The complete disappearance of the S-H band in FT-IR spectrum of N-acetyl-L-cysteine capped ZnSe nanocrystals was an indication over formation of Zn-thiol covalent bonds at the surface of the nanocrystals which results in passivation of small nanocrystals. The strong size-quantization regime was responsible of significant blue shift in absorption/emission spectra. Using the well-known calculations, band gap and Urbach energy of the ZnSe nanocrystals were measured and their average size was estimated optically to be around 4.6 nm along with the TEM image. A dark blue emission with higher relative intensity of excitonic to trap emissions (compared to conventional method), very narrow excitonic emission peak of about 16 nm and remarkable stability was obtained from the ZnSe nanocrystals.

  15. Extended Lyman-alpha emission from cold accretion streams

    CERN Document Server

    Rosdahl, J

    2011-01-01

    {Abridged} We investigate the observability of cold accretion streams at redshift 3 via Lyman-alpha radiation and the feasibility of cold accretion as the main driver behind giant Lya blobs (LABs). We run cosmological zoom simulations focusing on 3 halos spanning two orders of magnitude in mass, from 10^11 to 10^13 solar masses. We use a version of the AMR code Ramses that includes radiative transfer of UV photons, and we employ a refinement strategy that allows us to resolve accretion streams in their natural environment to an unprecedented level. For the first time, we self-consistently model self-shielding in the cold streams from the cosmological UV background, which enables us to accurately predict their temperatures, ionization states and Lya luminosities. We find the efficiency of gravitational heating in cold streams in a ~10^11 solar mass halo is around 10-20% throughout most of the halo but reaching much higher values close to the center. As a result most of the Lya luminosity comes from the circumg...

  16. Alfvenic behavior of alpha particle driven ion cyclotron emission in TFTR

    Energy Technology Data Exchange (ETDEWEB)

    Cauffman, S.; Majeski, R. [Princeton Plasma Physics Lab., NJ (United States); McClements, K.G. [UKAEA Government Division, Oxfordshire (United Kingdom). Euratom/UKAEA Fusion Association] [and others

    1995-07-01

    Ion cyclotron emission (ICE) has been observed during D-T discharges in the Tokamak Fusion Test Reactor (TFTR), using rf probes located near the top and bottom of the vacuum vessel. Harmonics of the alpha cyclotron frequency ({Omega}{sub {alpha}}) evaluated at the outer midplane plasma edge are observed at the onset of the beam injection phase of TFTR supershots, and persist for approximately 100-250 ms. These results are in contrast with observations of ICE in JET, in which harmonics of {Omega}{sub {alpha}} evolve with the alpha population in the plasma edge. Such differences are believed to be due to the fact that newly-born fusion alpha particles are super-Alfvenic near the edge of JET plasmas, while they are sub-Alfvenic near the edge of TFTR supershot plasmas. In TFTR discharges with edge densities such that newly-born alpha particles are super-Alfvenic, alpha cyclotron harmonics are observed to persist. These results are in qualitative agreement with numerical calculations of growth rates due to the magnetoacoustic cyclotron instability.

  17. Red shift of the band-edge photoluminescence emission and effects of annealing and capping agent on structural and optical properties of ZnO nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Verma, D.; Kole, A.K.; Kumbhakar, P., E-mail: pathik.kumbhakar@phy.nitdgp.ac.in

    2015-03-15

    Highlights: • Effect of annealing and capping on structural/optical properties of ZnO nanoparticles. • Red shifting in absorption and photoluminescence emission spectra is observed. • Tensile (compressive) strain is present in capped (uncapped) sample. • Synthesized low-toxic ZnO nanoparticles may find their application in bio-imaging. - Abstract: Use of nontoxic and biodegradable capping agents during the synthesis of nanomaterials has drawn a lot of research attention due to their potential applicability in biophotonic and bio-imaging devices. However, here we have reported the synthesis of an uncapped and biodegradable polyvinyl alcohol (PVA) capped ZnO nanoparticles (NPs), by using a simple chemical precipitation method at room temperature, followed by isochronal annealing of the as-synthesized sample at 200, 400, 500 and 600 °C for 2 h in air. The effects of using PVA and thermal annealing on the structural and optical properties of synthesized ZnO NPs have been reported. From the X-ray diffraction data analyses it has been observed that the use of PVA caused tensile strain in the annealed samples, whereas the samples synthesized without PVA capping showed compressive strain. For an estimation of strain and sizes of the NPs, three different models namely, uniform deformation model (UDM), uniform stress deformation model (USDM) and uniform deformation energy density model (UDEDM) have been used. The photoluminescence (PL) emission characteristics of the samples have been reported and they are found to consist of a strong near band-edge UV emission, which is systematically red shifted due to annealing from 371 to 383 nm for the capped and from 372 to 385 nm for the uncapped samples. Such biodegradable capped nanoparticles having UV PL emission might find potential applications as biophotonic materials.

  18. C IV and He II Line Emission of Lyman Alpha Blobs: Powered by Shock Heated Gas

    CERN Document Server

    Cabot, Samuel H C; Zheng, Zheng

    2016-01-01

    Utilizing {\\it ab initio} ultra-high resolution hydrodynamical simulations, we investigate the properties of the interstellar and circum-galactic medium of Ly$\\alpha$ Blobs (LABs) at $z=3$, focusing on three important emission lines: Ly$\\alpha$ 1216\\AA, \\heii 1640\\AA\\ and \\civ 1449\\AA. Their relative strengths provide a powerful probe of the thermodynamic properties of the gas when confronted with observations. By adjusting the dust attenuation effect using one parameter and matching the observed size-luminosity relation of LABs using another parameter, we show that our simulations can reproduce the observed \\civ/\\lya\\ and \\heii/\\lya\\ ratios adequately. This analysis provides the first successful physical model to account for simultaneously the LAB luminosity function, luminosity-size relation, and the \\civ/Ly$\\alpha$ and \\heii/Ly$\\alpha$ ratios, with only two parameters. The physical underpinning for this model is that, in addition to the stellar component for the \\lya\\ emission, the \\lya\\ and \\civ\\ emission...

  19. Physical properties of z~4 LBGs: differences between galaxies with and without Ly-alpha emission

    CERN Document Server

    Pentericci, L; Fontana, A; Salimbeni, S; Santini, P; De Santis, C; Gallozzi, S; Giallongo, E

    2007-01-01

    We have analysed the physical properties of z~4 Lyman Break Galaxies observed in the GOODS-S survey, in order to investigate the possible differences between galaxies where the Ly-alpha is present in emission, and those where the line is absent or in absorption. The objects have been selected from their optical color and then spectroscopically confirmed by Vanzella et al. (2005). From the public spectra we assessed the nature of the Ly-alpha emission and divided the sample into galaxies with Ly-alpha in emission and objects without Ly-alpha line (i.e. either absent or in absorption). We have then used the complete photometry, from U band to mid infrared from the GOODS-MUSIC database, to study the observational properties of the galaxies, such as UV spectral slopes and optical to mid-infrared colors, and the possible differences between the two samples. Finally through standard spectral fitting tecniques we have determined the physical properties of the galaxies, such as total stellar mass, stellar ages and so...

  20. Pulsar Polar Cap Heating and Surface Thermal X-Ray Emission I. Curvature Radiation Pair Fronts

    CERN Document Server

    Harding, A K; Harding, Alice K.; Muslimov, Alexander G.

    2001-01-01

    We investigate the effect of pulsar polar cap (PC) heating produced by positrons returning from the upper pair formation front. Our calculations are based on a self-consistent treatment of the pair dynamics and the effect of electric field screening by the returning positrons. We calculate the resultant X-ray luminosities, and discuss the dependence of the PC heating efficiencies on pulsar parameters, such as characteristic spin-down age, spin period, and surface magnetic field strength. In this study we concentrate on the regime where the pairs are produced in a magnetic field by curvature photons emitted by accelerating electrons. Our theoretical results are not in conflict with the available observational X-ray data and suggest that the effect of PC heating should significantly contribute to the thermal X-ray fluxes from middle-aged and old pulsars. The implications for current and future X-ray observations of pulsars are briefly outlined.

  1. Confirmation of a moving component in the $H-\\alpha$ emission line of LSI+61303

    CERN Document Server

    Zamanov, R K

    2000-01-01

    We report our attempts to detect and confirm a narrow moving component in the H-alpha emission line of the radio emitting Be/X-ray binary LSI+61 303 (V615 Cas, GT0236+610). The existence of this spectral feature was already suspected in the past. As a result, we find that this component does exist and that its radial velocity varies in agreement with the radio period of the system. We interpret it tentatively as due to a denser region, or bulge, orbiting near the outer edge of the H-alpha emitting disk.

  2. Effect of. cap alpha. -,. beta. -adrenergic receptor agonists and antagonists of the efflux of /sup 22/Na and uptake of /sup 42/K by rat brain cortical slices

    Energy Technology Data Exchange (ETDEWEB)

    Phillis, J.W.; Wu, P.H.; Thierry, D.L.

    1982-03-18

    The effects of norepinephrine on ion fluxes in rat brain cortical slices have now been ascertained. /sup 22/Na efflux and /sup 42/K influx are enhanced by norepinephrine. The increase in ion fluxes can be blocked by ouabain, phentolamine and propranolol, suggesting that the catecholamine activates a membrane sodium pump by a receptor-mediated step. The facilitation of /sup 22/Na efflux is stereospecific as demonstrated by the very weak action of D-norepinephrine at 10/sup -5/ M concentration. Various ..cap alpha..-adrenergic and ..beta..-adrenergic receptor agonists, including oxymetazoline, naphazoline, clonidine, tramazoline, methoxamine, phenylephrine, L-isoproterenol and methoxyphenamine are potent stimulants of the sodium pump as demonstrated by their enhancement of ion fluxes in rat brain cortical slices. The results are consistent with the hypothesis that norepinephrine hyperpolarizes central neurons by activating an ouabain-sensitive, receptor-mediated sodium pump.

  3. Deuteriation exchange (with the deuteriated catalyst surface) and the ratio of dehydrogenation and dehydration of. cap alpha. - and. beta. -substituted ethanols on basic oxides

    Energy Technology Data Exchange (ETDEWEB)

    Thomke, K.

    1977-01-01

    The pulsed reactions of ethanol, 1- and 2-propanol, 1- and 2-butanol, 2-methyl-2-propanol, and 3-pentanol on deuteriated magnesium, samarium, thorium, and lanthanum oxides showed that no deuterium was incorporated at a carbon of 2-methyl-2-propanol (i.e., that the reaction did not proceed by the E1cB mechanism); that all the secondary alcohols formed olefins and ketones and incorporated deuterium only in the ..beta..-position; and that primary alcohols formed olefins and aldehydes on all catalysts except lanthanum oxide (which catalyzed only dehydration of primary alcohols) and incorporated deuterium in the ..cap alpha..-position on magnesium and thorium oxide. The mechanism is discussed. Table.

  4. Ly\\alpha\\ emission line reconstruction for high-$z$ QSOs

    CERN Document Server

    Greig, Bradley; McGreer, Ian D; Gallerani, Simona; Haiman, Zoltán

    2016-01-01

    We introduce an intrinsic Ly\\alpha\\ emission line profile reconstruction method for high-$z$ quasars (QSOs). This approach utilises a covariance matrix of emission line properties obtained from a large, moderate-$z$ ($2 \\leq z \\leq 2.5$), high signal to noise (S/N > 15) sample of BOSS QSOs. For each QSO, we complete a Monte Carlo Markov Chain fitting of the continuum and emission line properties and perform a visual quality assessment to construct a large database of robustly fit spectra. With this dataset, we construct a covariance matrix to describe the correlations between the high ionisation emission lines Ly\\alpha, C IV, Si IV + O IV] and C III], and find it to be well approximated by an $N$-dimensional Gaussian distribution. This covariance matrix characterises the correlations between the line width, peak height and velocity offset from systemic while also allowing for the existence of broad and narrow line components for Ly\\alpha\\ and C IV. We illustrate how this covariance matrix allows us to statist...

  5. Can China afford to commit itself an emissions cap? An economic and political analysis

    NARCIS (Netherlands)

    Zhang, ZX

    2000-01-01

    As the world's second largest carbon emitter, China has long been criticised as a 'free-rider' enjoying benefits from other countries' efforts to abate greenhouse gas emissions but not taking due responsibilities of its own. China has been singled out as one of the major targets at the subsequent ne

  6. X-ray emission on hybird stars: ROSAT observations of alpha Trianguli Australis and iota Aurigae

    Science.gov (United States)

    Kashyap, V.; Rosner, R.; Harnden, F. R., Jr.; Maggio, A.; Micela, G.; Sciortino, S.

    1994-01-01

    We report on deep ROSAT observations of two Hybrid atmosphere stars, alpha TrA and iota Aur, and our analysis of these observations. We detect high-energy transient phenomena on alpha TrA and consider the implications of this discovery to the atmospheres of Hybrid stars. We detect iota Aur in the high-energy passband of ROSAT, implying the existence of multimillion degree plasma on the star. Our major results include the following: discovery of two large flare events, detected during pointed observations of alpha TrA; the demonstration that the flare emission most likely comes from the giant itself, rather than from a previously unseen low-mass companion star; the demonstration that the plasma characteristics associated with the flares and with the 'quiescent' component are essentially indistinguishable; and that the geometric dimensions of the emitting plasma are considerably smaller than the critical dimension characterizing stable 'hot' coronal loop structures. Our results suggest that alpha TrA does not have any steady X-ray emission consistent with theoretical expectations, and support the argument that Hybrid stars constitute a transitional type of object in which large-scale magnetic dynamo activity ceases, and the dominant spatial scales characterizing coronal structure rapidly decline as such stars evolve across the X-ray 'Dividing Line' in the H-R diagram.

  7. Lyman alpha emission from the first galaxies: Implications of UV backgrounds and the formation of molecules

    CERN Document Server

    Latif, M A; Spaans, M; Zaroubi, S

    2011-01-01

    The Lyman alpha line is a robust tracer of high redshift galaxies. We present estimates of Lyman alpha emission from a protogalactic halo illuminated by UV background radiation fields with various intensities. For this purpose, we performed cosmological hydrodynamics simulations with the adaptive mesh refinement code FLASH, including a detailed network for primordial chemistry,comprising the formation of primordial molecules, a multi-level model for the hydrogen atom as well as the photo-ionization and photo-dissociation processes in a UV background. We find that the presence of a background radiation field J_21 excites the emission of Lyman alpha photons, increasing the Lyman alpha luminosity up to two orders of magnitude. For a halo of \\sim 10^10 M_sun, we find that a maximum flux of 5 \\times 10^-15 erg cm^-2 s^-1 is obtained for J21 \\times f_esc = 0.1, where f_esc is the escape fraction of the ionizing radiation. Depending on the environmental conditions, the flux may vary by three orders of magnitude. For...

  8. Paschen-alpha Emission in the Gravitationally Lensed Galaxy SMM J163554.2+661225

    CERN Document Server

    Papovich, Casey; Rigby, Jane; Willmer, Christopher; Smith, J -D; Finkelstein, Steven; Egami, Eiichi; Rieke, Marcia

    2009-01-01

    We report the detection of the Paschen-alpha emission line in the z=2.515 galaxy SMM J163554.2+661225 using Spitzer spectroscopy. SMM J163554.2+661225 is a sub-millimeter-selected infrared (IR)-luminous galaxy maintaining a high star-formation rate (SFR), with no evidence of an AGN from optical or infrared spectroscopy, nor X-ray emission. This galaxy is lensed gravitationally by the cluster Abell 2218, making it accessible to Spitzer spectroscopy. Correcting for nebular extinction derived from the H-alpha and Pa-alpha lines, the dust-corrected luminosity is L(Pa-alpha) = (2.57+/-0.43) x 10^43 erg s^-1, which corresponds to an ionization rate, Q = (1.6+/-0.3) x 10^55 photons s^-1. The instantaneous SFR is 171+/-28 solar masses per year, assuming a Salpeter-like initial mass function. The total IR luminosity derived using 70, 450, and 850 micron data is L(IR) = (5-10) x 10^11 solar luminosities, corrected for gravitational lensing. This corresponds to a SFR=90-180 solar masses per year, where the upper range i...

  9. Strong Ly$\\alpha$ Emission in the Proximate Damped Ly$\\alpha$ Absorption Trough toward the Quasar SDSS J095253.83$+$011422.0

    CERN Document Server

    Jiang, Peng; Pan, Xiang; Jiang, Ning; Shu, Xinwen; Wang, Huiyuan; Gu, Qiusheng; Li, Zhenzhen; Wu, Maochun; Shi, Xiheng; Ji, Tuo; Tian, Qiguo; Zhang, Shaohua

    2016-01-01

    SDSS J095253.83$+$011422.0 (SDSS J0952$+$0114) was reported by Hall et al. (2004) as an exotic quasar at $z_{em}=3.020$. In contrast to prominent broad metal--line emissions with FWHM$\\sim9000$~km~s$^{-1}$, only a narrow Ly$\\alpha$ emission line is present with FWHM$\\sim$1000~km~s$^{-1}$. The absence of broad Ly$\\alpha$ emission line has been a mystery for more than a decade. In this paper, we demonstrate that this is due to dark Proximate Damped Ly$\\alpha$ Absorption (PDLA) at $z_{abs}=3.010$ by identifying associated Lyman absorption line series from the damped Ly$\\beta$ up to Ly9, as well as the Lyman limit absorption edge. The PDLA cloud has a column density of $\\log N_{\\rm H\\,I}({\\rm cm}^{-2})=21.8\\pm0.2$, a metallicity of [Zn/H]$>-1.0$, and a spatial extent exceeding the Narrow Emission Line Region (NELR) of the quasar. With a luminosity of $L_{{\\rm Ly}\\alpha}\\sim10^{45}$~erg~s$^{-1}$, the residual Ly$\\alpha$ emission superposed on the PDLA trough is of two orders of magnitude stronger than previous rep...

  10. Ananlysis of Carbon Emission Reduction and Power Dominance between Single Manufacturer and Single Retailer in Regulatory Cap and Trade System

    Directory of Open Access Journals (Sweden)

    Liang-jie Xia

    2014-01-01

    Full Text Available In the cap and trade system, the paper analyses the Stackelberg game between the power asymmetrical retailer and manufacturer and designs a side-payment self-enforcing contract to resolve some arguments that the existing research overemphasizes spontaneity of participation in side-payment contracts design based on supply chain coordination and does not consider rationality and fairness of allocation of profit increment. Also, the numerical analysis was given. The research shows some important conclusions: in the supply chain, the dominant manufacturer is not able to encourage the retailer to improve its promotion level by increasing its carbon cutting level, but the optimal emission reduction level increases with the dominant retailer’s promotion level; the optimal promotion level, emission reduction, and product demand in a retailer leading supply chain are higher than those in a supply chain dominated by manufacturer; with the new side-payment self-enforcing contract, decentralized decision according to individual rationality incurs a collective reason effect in the centralized setting.

  11. No Evidence for Lyman-alpha Emission in Spectroscopy of z > 7 Candidate Galaxies

    CERN Document Server

    Caruana, Joseph; Wilkins, Stephen M; Stanway, Elizabeth R; Lacy, Mark; Jarvis, Matt J; Lorenzoni, Silvio; Hickey, Samantha

    2012-01-01

    We present Gemini/GNIRS spectroscopic observations of 4 z-band (z~7) dropout galaxies and VLT/XSHOOTER observations of one z-band dropout and 3 Y-band (z~8-9) dropout galaxies in the Hubble Ultra Deep Field, which were selected with Wide Field Camera 3 imaging on the Hubble Space Telescope. We find no evidence of Lyman-alpha emission with a typical 5-sigma sensitivity of 5X10^-18erg/cm^2/s, and we use the upper limits on Lyman-alpha flux and the broad-band magnitudes to constrain the rest-frame equivalent widths for this line emission. Accounting for incomplete spectral coverage, we survey 3.0 z-band dropouts and 2.9 Y-band dropouts to a Lyman-alpha rest-frame equivalent width limit > 120Ang (for an unresolved emission line); for an equivalent width limit of 50Ang the effective numbers of drop-outs surveyed fall to 1.2 z-band drop-outs and 1.5 Y-band drop-outs. A simple model where the fraction of high rest-frame equivalent width emitters follows the trend seen at z=3-6.5 is inconsistent with our non-detectio...

  12. Sensitized luminescence from water-soluble LaF3:Eu nanocrystals via partially-capped 1,10-phenanthroline: time-gated emission and multiple lifetimes.

    Science.gov (United States)

    Irfanullah, Mir; Bhardwaj, Navneet; Chowdhury, Arindam

    2016-08-02

    Water dispersible citrate-capped LaF3:Eu(5%) nanocrystals (NCs) have been partially surface-functionalized by 1,10-phenanthroline (phen) via a ligand exchange method to produce novel water dispersed citrate/phen-capped LaF3:Eu(5%) NCs in which citrate ligands preserve the water dispersibility of the NCs and phen ligands act as sensitizers of surface Eu(3+)-dopant sites. The partial ligand exchange and the formation of water dispersed NCs have been monitored by (1)H NMR spectroscopy, as well as luminescence measurements at different time intervals during the reaction. These NCs display a distinct phen-sensitized Eu(3+)-emission profile with enhanced intensity in water as compared to the emission profile and intensity obtained upon direct excitation. Time-resolved (or time-gated) emission spectroscopy (TRES) has been used to probe PL dynamics of Eu(3+)-sites of LaF3:Eu(5%) NCs by taking advantage of selectively sensitizing surface Eu(3+)-dopant sites by phen ligands as well as by exciting all the Eu(3+)-sites in the NCs upon direct excitation. TRES upon direct excitation of the citrate-capped LaF3:Eu(5%) NCs reveals that Eu(3+)-dopants occupy at least three different sites, each with a different emission profile and lifetime, and emission from purely interior Eu(3+)-sites has been resolved due to their long lifetime as compared to the lifetime of purely surface and near surface Eu(3+)-sites. In contrast, the phen-sensitized emission from citrate/phen-capped LaF3:Eu(5%) NCs displays similar emission profiles and lifetimes in TRES measurements, which reveal that phen truly sensitizes purely surface dopant sites of the NCs in water, all of which have nearly the same local environment. The phen-sensitized Eu(3+)-emission of the NCs in water remains stable even upon addition of various buffer solutions at physiological pH, as well as upon addition of water-miscible organic solvents. Furthermore, the two-photon excitation (λex. = 720 nm) of these water-soluble phen-capped

  13. Quantitative autoradiography of alpha particle emission in geo-materials using the Beaver™ system

    Science.gov (United States)

    Sardini, Paul; Angileri, Axel; Descostes, Michael; Duval, Samuel; Oger, Tugdual; Patrier, Patricia; Rividi, Nicolas; Siitari-Kauppi, Marja; Toubon, Hervé; Donnard, Jérôme

    2016-10-01

    In rocks or artificial geo-materials, radioactive isotopes emitting alpha particles are dispersed according to the mineralogy. At hand specimen scale, the achievement of quantitative chemical mapping of these isotopes takes on a specific importance. Knowledge of the distribution of the uranium and thorium series radionuclides is of prime interest to several disciplines, from the geochemistry of uranium deposits, to the dispersion of uranium mill tailings in the biosphere. The disequilibrium of these disintegration chains is also commonly used for dating. However, some prime importance isotopes, such as 226Ra, are complicated to localize in geo-materials. Because of its high specific activity, 226Ra is found in very low concentrations ( ppq), preventing its accurate localization in rock forming minerals. This paper formulates a quantitative answer to the following question: at hand specimen scale, how can alpha emitters in geo-materials be mapped quantitatively? In this study, we tested a new digital autoradiographic method (called the Beaver™) based on a Micro Patterned Gaseous Detector (MPGD) in order to quantitatively map alpha emission at the centimeter scale rock section. Firstly, for two thin sections containing U-bearing minerals at secular equilibrium, we compared the experimental and theoretical alpha count rates, measured by the Beaver™ and calculated from the uranium content, respectively. We found that they are very similar. Secondly, for a set of eight homemade standards made up of a mixture of inactive sand and low-radioactivity mud, we compared the count rates obtained by the Beaver™ and by an alpha spectrometer. The results indicate (i) a linearity between both count rates, and (ii) that the count obtained by the Beaver™ can be estimated from the count obtained by the alpha spectrometry using a factor of 0.82.

  14. Spatial Correlation Between Dust and H$\\alpha$ Emission in Dwarf Irregular Galaxies

    CERN Document Server

    Jimmy,; Saintonge, Amélie; Accurso, Gioacchino; Brough, Sarah; Oliva-Altamirano, Paola; Salmon, Brett; Forrest, Ben

    2016-01-01

    Using a sample of dwarf irregular galaxies selected from the ALFALFA blind HI-survey and observed using the VIMOS IFU, we investigate the relationship between H$\\alpha$ emission and Balmer optical depth ($\\tau_{\\text{b}}$). We find a positive correlation between H$\\alpha$ luminosity surface density and Balmer optical depth in 8 of 11 at $\\geq$ 0.8$\\sigma$ significance (6 of 11 at $\\geq$ 1.0$\\sigma$) galaxies. Our spaxels have physical scales ranging from 30 to 80 pc, demonstrating that the correlation between these two variables continues to hold down to spatial scales as low as 30 pc. Using the Spearman's rank correlation coefficient to test for correlation between $\\Sigma_{\\text{H}\\alpha}$ and $\\tau_{\\text{b}}$ in all the galaxies combined, we find $\\rho = 0.39$, indicating a positive correlation at 4$\\sigma$ significance. Our low stellar-mass galaxy results are in agreement with observations of emission line regions in larger spiral galaxies, indicating that this relationship is independent of the size of ...

  15. Sources of Variability in Alpha Emissivity Measurements at LA and ULA Levels, a Multicenter Study

    CERN Document Server

    McNally, B D; Warburton, W K; Autran, J; Clark, B M; Cooley, J; Gordon, M S; Zhu, Z

    2014-01-01

    Alpha emissivity measurements are important in the semiconductor industry for assessing the suitability of materials for use in production processes. A recently published round-robin study that circulated the same samples to several alpha counting centers showed wide center-to-center variations in measured alpha emissivity. A separate analysis of these results hypothesized that much of the variation might arise from differences in sample-to-entrance window separations. XIA recently introduced an ultra low background counter, the UltraLo-1800 (UltraLo), that operates in a fundamentally different manner from the proportional counters used at most of the centers in the original study. In particular, by placing the sample within the counting volume, it eliminates the sample-to-entrance window separation issue noted above, and so offers an opportunity to test this hypothesis. In this work we briefly review how the UltraLo operates and describe a new round-robin study conducted entirely on UltraLo instruments using...

  16. Sources of variability in alpha emissivity measurements at LA and ULA levels, a multicenter study

    Science.gov (United States)

    McNally, Brendan D.; Coleman, Stuart; Warburton, William K.; Autran, Jean-Luc; Clark, Brett M.; Cooley, Jodi; Gordon, Michael S.; Zhu, Zhengmao

    2014-06-01

    Alpha emissivity measurements are important in the semiconductor industry for assessing the suitability of materials for use in production processes. A recently published round-robin study that circulated the same samples to several alpha counting centers showed wide center-to-center variations in measured alpha emissivity. A separate analysis of these results hypothesized that much of the variation might arise from differences in sample-to-entrance window separations. XIA recently introduced an ultra low background counter, the UltraLo-1800 (“UltraLo”), that operates in a fundamentally different manner from the proportional counters used at most of the centers in the original study. In particular, by placing the sample within the counting volume, it eliminates the sample-to-entrance window separation issue noted above, and so offers an opportunity to test this hypothesis. In this work we briefly review how the UltraLo operates and describe a new round-robin study conducted entirely on UltraLo instruments using a set of standard samples that included two samples used in the original study. This study shows that, for LA (“Low Alpha” between 2 and 50 α/khr-cm2) sample measurements, the only remaining site-to-site variations were due to counting statistics. Variations in ULA (“Ultra-Low Alpha”background.

  17. EU emission trading. Requirement of adaptation of the Cap as a consequence of external shocks and unexpected developments?; EU-Emissionshandel. Anpassungsbedarf des Caps als Reaktion auf externe Schocks und unerwartete Entwicklungen?

    Energy Technology Data Exchange (ETDEWEB)

    Diekmann, Jochen [DIW, Berlin (Germany)

    2012-11-15

    The effectivity of the European emission trading system (EU-ETS) with respect to the reduction of greenhouse gas emissions based essentially on the quantity of the emission caps. The regional, sectorial and temporal boundaries of this system as well as the regulations covering international flexible mechanisms and banking have to be considered in the evaluation of the effectivity of the EU-ETS. Under this aspect, the authors of the contribution under consideration discuss the advantages and disadvantages of the different variants of adjustment. First of all, the criteria for an identification of a possible justified needs of adaptation are investigated. Furthermore, the authors discuss the question about suitable points in time for an intervention.

  18. Probable alpha and $14$^C cluster emission from hyper Ac nuclei

    CERN Document Server

    Santhosh, K P

    2013-01-01

    A systematic study on the probability for the emission of 4^He and 14^C cluster from hyper ${207-234}^$Ac and non-strange normal ${207-234}^$Ac nuclei are performed for the first time using our fission model, the Coulomb and proximity potential model (CPPM). The predicted half lives show that hyper ${207-234}^$Ac nuclei are unstable against 4^He emission and 14^C emission from hyper ${217-228}^$Ac are favorable for measurement. Our study also show that hyper ${207-234}^$Ac are stable against hyper 4^He and 14^C emission. The role of neutron shell closure (N=126) in hyper 214^Fr daughter and role of proton/ neutron shell closure (Z =82, N =126) in hyper 210^Bi daughter are also revealed. As hyper-nuclei decays to normal nuclei by mesonic/non-mesonic decay and since most of the predicted half lives for 4^He and 14^C emission from normal Ac nuclei are favourable for measurement, we presume that alpha and 14^C cluster emission from hyper Ac nuclei can be detected in laboratory in a cascade (two-step) process.

  19. Probable alpha and {sup 14}C cluster emission from hyper Ac nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Santhosh, K.P. [Kannur University, Swami Anandatheertha Campus, School of Pure and Applied Physics, Payyanur (India)

    2013-10-15

    A systematic study on the probability for the emission of {sup 4}He and {sup 14}C cluster from hyper {sub {Lambda}}{sup 207-234}Ac and non-strange normal {sup 207-234}Ac nuclei are performed for the first time using our fission model, the Coulomb and proximity potential model (CPPM). The predicted half lives show that hyper {sub {Lambda}}{sup 207-234}Ac nuclei are unstable against {sup 4}He emission and {sup 14}C emission from hyper {sub {Lambda}}{sup 217-228}Ac are favorable for measurement. Our study also show that hyper {sub {Lambda}}{sup 207-234}Ac are stable against hyper {sub {Lambda}}{sup 4}He and {sub {Lambda}}{sup 14}C emission. The role of neutron shell closure (N = 126) in hyper {sub {Lambda}}{sup 214}Fr daughter and role of proton/neutron shell closure (Z {approx} 82, N = 126) in hyper {sub {Lambda}}{sup 210}Bi daughter are also revealed. As hyper-nuclei decays to normal nuclei by mesonic/non-mesonic decay and since most of the predicted half lives for {sup 4}He and {sup 14}C emission from normal Ac nuclei are favourable for measurement, we presume that alpha and {sup 14}C cluster emission from hyper Ac nuclei can be detected in laboratory in a cascade (two-step) process. (orig.)

  20. HeII emission in Lyman-alpha nebulae: AGN or cooling radiation?

    CERN Document Server

    Scarlata, C; Teplitz, H I; Bridge, C; Francis, P; Palunas, P; Siana, B; Williger, G M; Woodgate, B

    2009-01-01

    We present a study of an extended Lyman-alpha (Lya) nebula located in a known overdensity at z~2.38. The data include multiwavelength photometry covering the rest-frame spectral range from 0.1 to 250um, and deep optical spectra of the sources associated with the extended emission. Two galaxies are associated with the Lya nebula. One of them is a dust enshrouded AGN, while the other is a powerful starburst, forming stars at >~600 Msol/yr. We detect the HeII emission line at 1640A in the spectrum of the obscured AGN, but detect no emission from other highly ionized metals (CIV or NV) as is expected from an AGN. One scenario that simultaneously reproduces the width of the detected emission lines, the lack of CIV emission, and the geometry of the emitting gas, is that the HeII and the Lya emission are the result of cooling gas that is being accreted on the dark matter halo of the two galaxies, Ly1 and Ly2. Given the complexity of the environment associated with our Lya nebula it is possible that various mechanism...

  1. Lyman alpha emission in starbursts: implications for galaxies at high redshift

    CERN Document Server

    Mas-Hesse, J M; Tenorio-Tagle, G; Leitherer, C; Terlevich, R J; Terlevich, E

    2003-01-01

    We present the results of a high resolution UV 2-D spectroscopic survey of star forming galaxies observed with HST-STIS. Our main aim was to map the Lyman alpha profiles to learn about the gas kinematics and its relation with the escape of Lyman alpha photons and to detect extended Lyman alpha emission due to scattering in gaseous halos. We have combined our data with previously obtained UV spectroscopy on other three star-forming galaxies. We find that the P-Cygni profile is spatially extended, smooth and spans several kiloparsecs covering a region much larger than the starburst itself. We propose a scenario whereby an expanding super-shell is generated by the interaction of the combined stellar winds and supernova ejecta from the young starbursts, with an extended low density halo. The variety of observed Lyman alpha profiles both in our sample and in high redshift starbursts is explained as phases in the time evolution of the super-shell expanding into the disk and halo of the host galaxy. The observed sha...

  2. Iron K$\\alpha$ emission in type-I and type-II Active Galactic Nuclei

    CERN Document Server

    Ricci, Claudio; Paltani, Stephane; Ichikawa, Kohei; Gandhi, Poshak; Awaki, Hisamitsu

    2014-01-01

    The narrow Fe K$\\alpha$ line is one of the main signatures of the reprocessing of X-ray radiation from the material surrounding supermassive black holes, and it has been found to be omnipresent in the X-ray spectra of active galactic nuclei (AGN). In this work we study the characteristics of the narrow Fe K$\\alpha$ line in different types of AGN. Using the results of a large Suzaku study we find that Seyfert 2s have on average lower Fe K$\\alpha$ luminosities than Seyfert 1s for the same 10-50 keV continuum luminosity. Simulating dummy Sy1s and Sy2s populations using physical torus models of X-ray reflected emission, we find that this difference can be explained by means of different average inclination angles with respect to the torus, as predicted by the unified model. Alternative explanations include differences in the intensities of Compton humps or in the photon index distributions. We show that the ratio between the flux of the broad and narrow Fe K$\\alpha$ line in the 6.35-6.45 keV range depends on the ...

  3. A Further Measurement of the beta-Delayed alpha-Particle Emission of 16N

    CERN Document Server

    III, R H F; McDonald, J E; Wilds, E L

    2007-01-01

    We measured the beta-delayed alpha-particle emission spectrum of 16N with a sensitivity for beta-decay branching ratios of the order of 10-10. The 16N nuclei were produced using the d(15N,16N)p reaction with 70 MeV 15N beams and a deuterium gas target 7.5 cm long at a pressure of 1250 torr. The 16N nuclei were collected (over 10 s) using a thin aluminum foil with an areal density of 180 mu g/cm2 tilted at 7 Deg with respect to the beam. The activity was transferred to the counting area by means of a stepping motor in less than 3 s with the counting carried out over 8 s. The beta-delayed alpha-particles were measured using a time of flight method to achieve a sufficiently low background. Standard calibration sources (148Gd, 241Am, 208,209Po, and 227Ac) as well as alpha-particles and 7Li from the 10B(n,alpha)7Li reaction were used for an accurate energy calibration. The energy resolution of the catcher foil (180-220 keV) was calculated and the time of flight resolution (3-10 nsec) was measured using the beta-de...

  4. The Properties of H{\\alpha} Emission-Line Galaxies at $z$ = 2.24

    CERN Document Server

    An, F X; Wang, W -H; Huang, J -S; Kong, X; Wang, J -X; Fang, G W; Zhu, F; Gu, Q -S; Wu, H; Hao, L; Xia, X -Y

    2014-01-01

    Using deep narrow-band $H_2S1$ and $K_{s}$-band imaging data obtained with CFHT/WIRCam, we identify a sample of 56 H$\\alpha$ emission-line galaxies (ELGs) at $z=2.24$ with the 5$\\sigma$ depths of $H_2S1=22.8$ and $K_{s}=24.8$ (AB) over 383 arcmin$^{2}$ area in the ECDFS. A detailed analysis is carried out with existing multi-wavelength data in this field. Three of the 56 H$\\alpha$ ELGs are detected in Chandra 4 Ms X-ray observation and two of them are classified as AGNs. The rest-frame UV and optical morphologies revealed by HST/ACS and WFC3 deep images show that nearly half of the H$\\alpha$ ELGs are either merging systems or with a close companion, indicating that the merging/interacting processes play a key role in regulating star formation at cosmic epoch z=2-3; About 14% are too faint to be resolved in the rest-frame UV morphology due to high dust extinction. We estimate dust extinction form SEDs. We find that dust extinction is generally correlated with H$\\alpha$ luminosity and stellar mass (SM). Our res...

  5. A Survey for H-alpha Emission from Late L dwarfs and T dwarfs

    CERN Document Server

    Pineda, J Sebastian; Kirkpatrick, J Davy; Cotter, Garret; Kao, Melodie M; Mooley, Kunal

    2016-01-01

    Recently, studies of brown dwarfs have demonstrated that they possess strong magnetic fields and have the potential to produce radio and optical auroral emissions powered by magnetospheric currents. This emission provides the only window on magnetic fields in the coolest brown dwarfs and identifying additional benchmark objects is key to constraining dynamo theory in this regime. To this end, we conducted a new red optical (6300 - 9700 Angstrom) survey with the Keck telescopes looking for H-alpha emission from a sample of late L dwarfs and T dwarfs. Our survey gathered optical spectra for 29 targets, 18 of which did not have previous optical spectra in the literature, greatly expanding the number of moderate resolution (R~2000) spectra available at these spectral types. Combining our sample with previous surveys, we confirm an H-alpha detection rate of 9.2 (+3.5/-2.1) % for L and T dwarfs in the optical spectral range of L4 - T8. This detection rate is consistent with the recently measured detection rate for ...

  6. Lyman-alpha and CIII] Emission in z=7-9 Galaxies: Accelerated Reionization Around Luminous Star Forming Systems?

    CERN Document Server

    Stark, Daniel P; Charlot, Stephane; Chevallard, Jacopo; Tang, Mengtao; Belli, Sirio; Zitrin, Adi; Mainali, Ramesh; Gutkin, Julia; Vidal-Garcia, Alba; Bouwens, Rychard; Oesch, Pascal

    2016-01-01

    We discuss new Keck/MOSFIRE spectroscopic observations of four luminous galaxies at z~7-9 selected to have intense optical line emission by Roberts-Borsani et al. (2016). Previous follow-up has revealed Lyman-alpha in two of the four galaxies. Our new MOSFIRE observations confirm that Lyman-alpha is present in the entire sample. We detect Lyman-alpha emission in COS-zs7-1, confirming its redshift as z=7.154, and we detect Lyman-alpha in EGS-zs8-2 at z=7.477, verifying a tentative detection presented in an earlier study. The ubiquity of Lyman-alpha in this sample is puzzling given that the IGM is likely significantly neutral over 77 is expected to be strongly luminosity-dependent, with the most effective transmission occurring in systems with intense star formation.

  7. Spin-polarized x-ray emission of 3d transition-metal ions : A comparison via K alpha and K beta detection

    NARCIS (Netherlands)

    Wang, Xin; deGroot, F.M.F.; Cramer, SP

    1997-01-01

    This paper demonstrates that spin-polarized x-ray-excitation spectra can be obtained using K alpha emission as well as K beta lines. A spin-polarized analysis of K alpha x-ray emission and the excitation spectra by K alpha detection on a Ni compound is reported. A systematic analysis of the first-ro

  8. The Lyman-$\\alpha$ emission in local Star-Forming Galaxies Scenario and Connection with Primeval Galaxies

    CERN Document Server

    Kunth, D; Terlevich, R J; Tenorio-Tagle, G

    1998-01-01

    We review the Lyan alpha emission in local star-forming galaxies. In most cases as already shown by the IUE, the emission is absent or much weaker than expected. This occurs because Lyman alpha photons can be resonantly scattered by the neutral gas and destroyed by even very low amounts of dust. However new Hubble Space Telescope observations (HST) indicate that other factors such as the velocity structure of the gas play a crucial role. Gas flows are likely to occur as powered by the kinetic energy released via stellar winds and supernova. We propose a scenario based on the hydrodynamics of superbubbles powered by massive bursts of star formation that naturally accounts for the variety of Lyman alpha line detections in star-forming galaxies. We caution with the attempts to derive the co-moving star formation rate at high redshift from Lyman alpha emission searches.

  9. Using k-alpha emission to determine fast electron spectra using the Hybrid code ZEPHYROS

    CERN Document Server

    White, Thomas; Gregori, Gianluca

    2014-01-01

    A high intensity laser-solid interaction invariably drives a non-thermal fast electron current through the target, however characterizing these fast electron distributions can prove difficult. An understanding of how these electrons propagate through dense materials is of fundamental interest and has applications relevant to fast ignition schemes and ion acceleration. Here, we utilize an upgraded version of the Hybrid code ZEPHYROS to demonstrate how the resulting k-alpha emission from such an interaction can be used as a diagnostic to obtain the characteristic temperature, divergence and total energy of the fast electron population.

  10. IUE high resolution spectrophotometry of H Ly alpha emission from the local interstellar medium

    Science.gov (United States)

    Clarke, J. T.; Bowyer, S.; Fahr, H. J.; Lay, G.

    1984-01-01

    IUE high dispersion spectra of resonantly scattered solar Ly alpha emission from H moving into the solar system with the local interstellar wind are reported which are based on observations conducted in April 1981 and April 1983. A heliocentric velocity of -29 + or - 5 km/s has been observed from the ISW component along with a surface brightness which has decreased from about 1000 to 800 Rayleighs over the two-year interval. A preliminary derivation of the velocity of the ISM at large distances from the sun yields a value of 25.6 + or - 5 km/s.

  11. Constraints on uncertainties and their application to the emission probabilities of alpha-particles

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, A.M. (Dept. de Fisica, Univ. de Extremadura, Badajoz (Spain)); Tome, F.V. (Dept. de Fisica, Univ. de Extremadura, Badajoz (Spain)); Diaz Bejarano, J. (Dept. de Fisica, Univ. de Extremadura, Badajoz (Spain))

    1994-03-08

    It often happens that the mean values of certain quantities are subject to constraints as, for example, when a sum is known exactly although the individual contributions have been measured independently and their corresponding uncertainties assigned. In this paper, the influence of a constraint on the final expression of the results is studied in detail, and is illustrated in the alpha-particle emission probabilities for several nuclides from nuclear data tables. A simple rule emerges: If the mean values must add to 100% and if one of the variances is greater than half the sum of all the variances, then the precision in the expression of the results can be improved. (orig.)

  12. Afterglow-reabsorbed H/sub alpha/ line delay effect in an expanding laser plasma

    Energy Technology Data Exchange (ETDEWEB)

    Derzhiev, V.I.; Zhidkov, A.G.; Maiorov, S.A.; Yakovlenko, S.I.

    1987-11-28

    The absorption of H/sub ..cap alpha../ line radiation is shown to lead to delay and even to non-monotonic afterglowing if observed along the 'line' of the expanding laser plasma. This makes it possible to explain the emission character of the H/sub ..cap alpha../ line of the O VIII ion (lambda = 10.2 nm) in experiments with 'Novette' set-ups.

  13. K-Alpha Emission Spectra From Non-Equilibrium Ionizing Plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, V L; Decaux, V; Beiersdorfer, P

    2004-12-16

    K{alpha} X-ray emission spectra from highly charged Fe ions have been theoretically predicted using a detailed and systematic spectral model. Account has been taken of the fundamental atomic radiative-emission processes associated with inner-shell electron collisional excitation and ionization, as well as dielectronic recombination. Particular emphasis has been directed at extreme non-equilibrium or transient-ionization conditions, which can occur in astrophysical and tokamak plasmas. Good agreement has been found in comparisons with spectral observations on the EBIT-II electron beam ion trap at the Lawrence Livermore National Laboratory. We have identified spectral features that can serve as diagnostics of the electron density, the line-formation mechanism, and the charge-state distribution.

  14. Spatially Resolved Emission of a z~3 Damped Lyman Alpha Galaxy with Keck/OSIRIS IFU

    Science.gov (United States)

    Christenson, Holly; Jorgenson, Regina

    2017-01-01

    The damped Lyman alpha (DLA) class of galaxies contains most of the neutral hydrogen gas over cosmic time. Few DLAs have been detected directly, which limits our knowledge of fundamental properties like size and mass. We present Keck/OSIRIS infrared integral field spectroscopy (IFU) observations of a DLA that was first detected in absorption toward a background quasar. Our observations use the Keck Laser Guide Star Adaptive Optics system to reduce the point-spread function of the quasar, making it possible to spatially resolve the DLA emission. We map this emission in O[III] 5007 Å. At redshift z~3, this DLA represents one of the highest redshift DLAs mapped with IFU spectroscopy. We present measurements of the star formation rate, metallicity, and gas mass of the galaxy.This project was supported in part by the NSF REU grant AST-1358980 and by the Nantucket Maria Mitchell Association.

  15. HST Emission Line Galaxies at z ~ 2: Comparing Physical Properties of Lyman Alpha and Optical Emission Line Selected Galaxies

    CERN Document Server

    Hagen, Alex; Behrens, Christoph; Ciardullo, Robin; Gebhardt, Henry S Grasshorn; Gronwall, Caryl; Bridge, Joanna S; Fox, Derek B; Schneider, Donald P; Trump, Jonathan R; Blanc, Guillermo A; Chiang, Yi-Kuan; Chonis, Taylor S; Finkelstein, Steven L; Hill, Gary J; Jogee, Shardha; Gawiser, Eric

    2015-01-01

    We compare the physical and morphological properties of z ~ 2 Lyman-alpha emitting galaxies (LAEs) identified in the HETDEX Pilot Survey and narrow band studies with those of z ~ 2 optical emission line galaxies (oELGs) identified via HST WFC3 infrared grism spectroscopy. Both sets of galaxies extend over the same range in stellar mass (7.5 < logM < 10.5), size (0.5 < R < 3.0 kpc), and star-formation rate (~1 < SFR < 100). Remarkably, a comparison of the most commonly used physical and morphological parameters -- stellar mass, half-light radius, UV slope, star formation rate, ellipticity, nearest neighbor distance, star formation surface density, specific star formation rate, [O III] luminosity, and [O III] equivalent width -- reveals no statistically significant differences between the populations. This suggests that the processes and conditions which regulate the escape of Ly-alpha from a z ~ 2 star-forming galaxy do not depend on these quantities. In particular, the lack of dependence on ...

  16. Synthesis of biological markers in fossil fuels. 4. C/sub 27/, C/sub 28/, and C/sub 29/ 13. beta. ,17. cap alpha. (H)-diasteranes

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, P.E.; Nelson, D.A.; Watt, D.S.; Reibenspies, J.H.; Anderson, O.P.; Seifert, W.K.; Moldowan, J.M.

    1985-12-27

    The rearrangement of 5-cholestene to (20epsilon)-13(17)-diacholestenes, separation of C-20 epimers, and further reduction provided an unambiguous synthesis of the biomarkers (20R)- and (20S)-13..beta..,17..cap alpha..(H)-diacholestanes. Repetition of this sequence using (24R)-5-campestene or (24R)-5-stigmastene provided the analogous C/sub 28/ and C/sub 29/ diasteranes. 15 references, 1 figure.

  17. Air Dispersion Modeling for the INL Application for a Synthetic Minor Sitewide Air Quality Permit to Construct with a Facility Emission Cap Component

    Energy Technology Data Exchange (ETDEWEB)

    Sondrup, Andrus Jeffrey [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-10-01

    The Department of Energy Idaho Operations Office (DOE-ID) is applying for a synthetic minor, Sitewide, air quality permit to construct (PTC) with a facility emission cap (FEC) component from the Idaho Department of Environmental Quality (DEQ) for Idaho National Laboratory (INL) to limit its potential to emit to less than major facility limits for criteria air pollutants (CAPs) and hazardous air pollutants (HAPs) regulated under the Clean Air Act. This document is supplied as an appendix to the application, Idaho National Laboratory Application for a Synthetic Minor Sitewide Air Quality Permit to Construct with a Facility Emissions Cap Component, hereafter referred to as “permit application” (DOE-ID 2015). Air dispersion modeling was performed as part of the permit application process to demonstrate pollutant emissions from the INL will not cause a violation of any ambient air quality standards. This report documents the modeling methodology and results for the air dispersion impact analysis. All CAPs regulated under Section 109 of the Clean Air Act were modeled with the exception of lead (Pb) and ozone, which are not required to be modeled by DEQ. Modeling was not performed for toxic air pollutants (TAPs) as uncontrolled emissions did not exceed screening emission levels for carcinogenic and non-carcinogenic TAPs. Modeling for CAPs was performed with the EPA approved AERMOD dispersion modeling system (Version 14134) (EPA 2004a) and five years (2000-2004) of meteorological data. The meteorological data set was produced with the companion AERMET model (Version 14134) (EPA 2004b) using surface data from the Idaho Falls airport, and upper-air data from Boise International Airport supplied by DEQ. Onsite meteorological data from the Grid 3 Mesonet tower located near the center of the INL (north of INTEC) and supplied by the local National Oceanic and Atmospheric Administration (NOAA) office was used for surface wind directions and wind speeds. Surface data (i

  18. Resolution of the discrepancy between Balmer alpha emission rates, the solar Lyman beta flux, and models of geocoronal hydrogen concentration

    Science.gov (United States)

    Levasseur, A.-C.; Meier, R. R.; Tinsley, B. A.

    1976-01-01

    New satellite Balmer alpha measurements and solar Lyman beta flux and line profile measurements, together with new measurements of the zodiacal light intensity used in correcting both ground and satellite Balmer alpha measurements for the effects of the Fraunhofer line in the zodiacal light, have been used in a reevaluation of the long-standing discrepancy between ground-based Balmer alpha emission rates and other geocoronal hydrogen parameters. The solar Lyman beta line center flux is found to be (4.1 plus or minus 1.3) billion photons per sq cm per sec per angstrom at S(10.7) equals 110 and, together with a current hydrogen model which has 92,000 atoms per cu cm at 650 km for T(inf) equals 950 K, gives good agreement between calculated Balmer alpha emission rates and the ground-based and satellite measurements.

  19. Copernicus observations of Ly-alpha and Mg II emission from HR 1099 /V711 Tauri/ and UX Ari

    Science.gov (United States)

    Weiler, E. J.

    1978-01-01

    Ultraviolet observations of two RS CVn binaries obtained with Copernicus are described. High-resolution (0.05 A) U1 observations indicate that both HR 1099 and UX Ari display broad Ly-alpha emission. The Ly-alpha emission strength from HR 1099 is variable and seems to be correlated with orbital phase, while the UX Ari results indicate no significant variation. Moderate resolution (0.51 A) V2 scans of both systems show variable Mg II h and k emission-line profiles which usually matched the velocity of the more active star in each binary. Additionally, displaced emission components were seen at velocities of up to + or - 250 km/s, indicative of high-velocity gas motions. The radial velocities of these emission features from HR 1099 are marginally correlated with orbital phase. Highly active and variable chromospheric phenomena are found to be the most consistent explanation of these results.

  20. Experimental Study of Two-Alpha Emission from High-Lying Excited States of 17'18^Ne

    Institute of Scientific and Technical Information of China (English)

    徐新星; 林承键; 贾会明; 杨峰; 贾飞; 吴振东; 张世涛; 刘祖华; 张焕乔; 徐瑚珊; 孙志宇; 王建松; 胡正国; 王猛; 陈若富; 张雪荧; 李琛; 雷祥国; 徐治国; 肖国青

    2012-01-01

    The experiments of two-alpha emission from 17,18^Ne excited levels were performed at the HIRFL-RIBLL facility of the Institute of Modern Physics, Lanzhou. The beams of 17^Ne at the energy of 49.9 MeV/u and lSNe at 51.8 MeV/u bombarded a 197Au target to populate excited states of 17,18^Ne via Coulomb excitation. Complete kinematics measurements were achieved by the detectors of a silicon strip and CsI+PIN array. The experimental results combined with simple MC simulations show the characteristic of sequential two-alpha emission via 140 excited states for lSNe. The results of two-alpha emission from 17^Ne are preliminary and need further analyses.

  1. Detection of HI in Emission in the Lyman Alpha Emitting Galaxy Haro 11

    CERN Document Server

    Pardy, Stephen A; Östlin, Göran; Hayes, Matthew; Bergvall, Nils

    2016-01-01

    We present the first robust detection of HI 21 cm emission in the blue compact galaxy Haro 11 using the 100m Robert C. Byrd Green Bank Telescope (GBT). Haro 11 is a luminous blue compact galaxy with emission in both Lyman Alpha and the Lyman continuum. We detect (5.1 $\\pm$ 0.7 $\\times$10$^8$) M$_{\\odot}$ of HI gas at an assumed distance of 88 Mpc, making this galaxy HI deficient compared to other local galaxies with similar optical properties. Given this small HI mass, Haro 11 has an elevated M$_{H2}$/M$_{HI}$ ratio and a very low gas fraction compared to most local galaxies, and contains twice as much mass in ionized hydrogen as in neutral hydrogen. The HI emission has a linewidth of 71 kms$^{-1}$ and is offset 60 kms$^{-1}$ redward of the optical line center. It is undergoing a starburst after a recent merger which has elevated the star formation rate, and will deplete the gas supply in $<$ 0.2 Gyr. Although this starburst has elevated the SFR compared to galaxies with similar HI masses and linewidths, H...

  2. Magellan LDSS3 emission confirmation of galaxies hosting metal-rich Lyman-alpha absorption systems

    CERN Document Server

    Straka, Lorrie A; York, Donald G; Bowen, David V; Florian, Michael; Kulkarni, Varsha P; Lundgren, Britt; Peroux, Celine

    2015-01-01

    Using the Low Dispersion Survey Spectrograph 3 at the Magellan II Clay Telescope in Chile, we target candidate absorption host galaxies detected in deep optical imaging (reaching limiting apparent magnitudes of 23.0-26.5 in g; r; i; and z filters) in the fields of three QSOs, each of which shows the presence of high metallicity, strong NHI absorption systems in their spectra (Q0826-2230: zabs=0.9110, Q1323-0021: zabs = 0.7160, Q1436-0051: zabs = 0.7377; 0.9281). We confirm host galaxies at redshifts 0.7387, 0.7401, and 0.9286 for two out of four of the Ly-alpha absorption systems. For these systems, we are able to determine the SFRs; impact parameters (known from previous imaging detections); the velocity shift between the absorption and emission redshifts; and, for one system, also the emission metallicity. Based on previous photometry, we find these galaxies have L>L*. The SFRs for these galaxies, based on [O II] emission, are in the range 11-25 M_sol/yr (uncorrected for dust), while the impact parameters l...

  3. The Stacked Lyman-Alpha Emission Profile from the Circum-Galactic Medium of z~2 Quasars

    CERN Document Server

    Battaia, Fabrizio Arrigoni; Cantalupo, Sebastiano; Prochaska, J Xavier

    2016-01-01

    In the context of the FLASHLIGHT survey, we obtained deep narrow band images of 15 $z\\sim2$ quasars with GMOS on Gemini-South in an effort to measure Ly$\\alpha$ emission from circum- and inter-galactic gas on scales of hundreds of kpc from the central quasar. We do not detect bright giant Ly$\\alpha$ nebulae (SB~10$^{-17}$ erg s$^{-1}$ cm$^{-2}$ arcsec$^{-2}$ at distances >50 kpc) around any of our sources, although we routinely ($\\simeq47$%) detect smaller scale <50 kpc Ly$\\alpha$ emission at this SB level emerging from either the extended narrow emission line regions powered by the quasars or by star-formation in their host galaxies. We stack our 15 deep images to study the average extended Ly$\\alpha$ surface brightness profile around $z\\sim2$ quasars, carefully PSF-subtracting the unresolved emission component and paying close attention to sources of systematic error. Our analysis, which achieves an unprecedented depth, reveals a surface brightness of SB$_{\\rm Ly\\alpha}\\sim10^{-19}$ erg s$^{-1}$ cm$^{-2}...

  4. XMM-Newton Observation of Fe K(alpha) Emission from a BAL QSO: Mrk 231

    Science.gov (United States)

    Turner, T. J.; Kraemer, S. B.

    2003-01-01

    We present results from a 20 ksec XMM-Newton observation of Mrk 231. EPIC spectral data reveal strong line emission due to Fe K alpha, which has rarely been detected in this class, as BAL QSOs are very faint in the X-ray band. The line energy is consistent with an origin in neutral Fe. The width of the line is equivalent to a velocity dispersion approximately 18,000 kilometers per second and thus the line may be attributed to transmission and/or reflection from a distribution of emitting clouds. If, instead, the line originates in the accretion disk then the line strength and flat X-ray continuum support some contribution from a reflected component, although the data disfavor a model where the hard X-ray band is purely reflected X-rays. The line parameters are similar to those obtained for the Fe Ka line detected in another BAL QSO, H1413 + 117.

  5. Rotation and H-alpha Emission Above and Below the Substellar Boundary

    CERN Document Server

    Basri, G S

    2000-01-01

    I present the results of a multiyear survey of very low mass stars and brown dwarfs, at high spectral resolution. The spectra were gathered with the HIRES echelle at the Keck Observatory. Some of these objects are stellar and others are substellar (or ambiguous). Early indications that such objects can be rapidly rotating but display little H-alpha emission turn out to be commonly true. This is the opposite of the relation between rotation and activity in solar-type stars. The H-alpha surface flux drops precipitously at the bottom of the main sequence, and seems to be related to the luminosity or temperature of the objects. There is a general trend to higher rotation velocities as one looks at objects of lower luminosity. I discuss several possible explanations for these results. The dynamos for these objects are probably fully turbulent, driven by convection, and thus more directly related to the object's luminosity. They may be quenched when the rotational velocities become too fast in comparison to the con...

  6. Boxy H$\\alpha$ Emission Profiles in Star-Forming Galaxies

    CERN Document Server

    Chen, Yan-Mei; Tremonti, Christy A; Shi, Yong; Jin, Yi-Fei

    2016-01-01

    We assemble a sample of disk star-forming galaxies from the Sloan Digital Sky Survey Data Release 7, studying the structure of H$\\alpha$ emission lines, finding a large fraction of this sample contains boxy H$\\alpha$ line profiles. This fraction depends on galaxy physical and geometric parameters in the following way: (1) it increases monotonically with star formation rate per unit area ($\\Sigma_{\\rm SFR}$), and stellar mass ($M_*$), with the trend being much stronger with $M_*$, from $\\sim$0% at $M_*=10^{10}M_{\\odot}$ to about 50% at $M_*=10^{11}M_\\odot$; (2) the fraction is much smaller in face-on systems than in edge-on systems. It increases with galaxy inclination ($i$) while $i < 60\\,^{\\circ}$ and is roughly a constant of 25% beyond this range; (3) for the sources which can be modeled well with two velocity components, blueshifted and redshifted from the systemic velocity, these is a positive correlation between the velocity difference of these two components and the stellar mass, with a slope similar...

  7. NUCLEIDE-LARA, a library for alpha, X and gamma emissions sorted by increasing energy; NUCLEIDE-LARA, bibliotheque des emissions alpha, X et gamma classees par ordre d'energie croissante

    Energy Technology Data Exchange (ETDEWEB)

    Be, M.M.; Dulieu, Ch.; Chiste, V

    2008-07-01

    The NUCLEIDE-LARA library presents, for almost 400 radionuclides of practical interest, the tables of alpha, X and gamma emissions sorted by increasing energy, as well as the associated intensity and radioactive half-life of the parent radionuclide. (authors)

  8. HH 666: Different kinematics from H{\\alpha} and [Fe II] emission provide a missing link between jets and outflows

    CERN Document Server

    Reiter, Megan; Kiminki, Megan M; Bally, John

    2015-01-01

    HH 666 is an externally irradiated protostellar outflow in the Carina Nebula for which we present new near-IR [Fe II] spectra obtained with the FIRE spectrograph at Magellan Observatory. Earlier H{\\alpha} and near-IR [Fe II] imaging revealed that the two emission lines trace substantially different morphologies in the inner ~40" of the outflow. H{\\alpha} traces a broad cocoon that surrounds the collimated [Fe II] jet that extends throughout the parent dust pillar. New spectra show that this discrepancy extends to their kinematics. Near-IR [Fe II] emission traces steady, fast velocities of +/- 200 km/s from the eastern and western limbs of the jet. We compare this to a previously published H{\\alpha} spectrum that reveals a Hubble-flow velocity structure near the jet-driving source. New, second-epoch HST/ACS H{\\alpha} images reveal the lateral spreading of the H{\\alpha} outflow lobe away from the jet axis. H{\\alpha} proper motions also indicate a sudden increase in the mass-loss rate ~1000 yr ago, while steady ...

  9. Lyman alpha emission from the first galaxies: Signatures of accretion and infall in the presence of line trapping

    CERN Document Server

    Latif, M A; Spaans, M; Zaroubi, S

    2011-01-01

    The formation of the first galaxies is accompanied by large accretion flows and virialization shocks, during which the gas is shock-heated to temperatures of $\\sim10^4$ K, leading to potentially strong fluxes in the Lyman alpha line. Indeed, a number of Lyman alpha blobs has been detected at high redshift. In this letter, we explore the origin of such Lyman alpha emission using cosmological hydrodynamical simulations that include a detailed model of atomic hydrogen as a multi-level atom and the effects of line trapping with the adaptive mesh refinement code FLASH. We see that baryons fall into the center of a halo through cold streams of gas, giving rise to a Lyman alpha luminosity of at least $\\rm 10^{44} erg s^{-1}$ at $\\rm z=4.7$, similar to observed Lyman alpha blobs. We find that a Lyman alpha flux of $\\rm 5.0\\times 10^{-17} erg cm^{-2} s^{-1}$ emerges from the envelope of the halo rather than its center, where the photons are efficiently trapped. Such emission can be probed in detail with the upcoming J...

  10. Two-source emission of relativistic alpha particles in 16O-Em interactions at 3.7 A GeV

    Institute of Scientific and Technical Information of China (English)

    Song Fu; Zhang Dong-Hai; Li Jun-Sheng

    2005-01-01

    The emission of alpha projectile fragments has been studied in 16O-emulsion interactions at 3.7 A GeV. The angular distributions of relativistic alphas cannot be explained by a clean-cut participant-spectator model. Therefore it is assumed that alphas originate from two distinct sources differing in their temperatures.

  11. The H$\\alpha$ emission of nearby M dwarfs and its relation to stellar rotation

    CERN Document Server

    Newton, Elisabeth R; Charbonneau, David; Berlind, Perry; Calkins, Michael L; Mink, Jessica

    2016-01-01

    The high-energy emission from low-mass stars is mediated by the magnetic dynamo. Although the mechanisms by which fully convective stars generate large-scale magnetic fields are not well understood, it is clear that, as for solar-type stars, stellar rotation plays a pivotal role. We present 270 new optical spectra of low-mass stars in the Solar Neighborhood. Combining our observations with those from the literature, our sample comprises 2202 measurements or non-detections of H$\\alpha$ emission in nearby M dwarfs. This includes 466 with photometric rotation periods. Stars with masses between 0.1 and 0.6 solar masses are well-represented in our sample, with fast and slow rotators of all masses. We observe a threshold in the mass-period plane that separates active and inactive M dwarfs. The threshold coincides with the fast-period edge of the slowly rotating population, at approximately the rotation period at which an era of rapid rotational evolution appears to cease. The well- defined active/inactive boundary ...

  12. Alpha-catenin-Dependent Recruitment of the Centrosomal Protein CAP350 to Adherens Junctions Allows Epithelial Cells to Acquire a Columnar Shape

    Science.gov (United States)

    Zurbano, Angel; Formstecher, Etienne; Martinez-Morales, Juan R.; Bornens, Michel; Rios, Rosa M.

    2015-01-01

    Epithelial morphogenesis involves a dramatic reorganisation of the microtubule cytoskeleton. How this complex process is controlled at the molecular level is still largely unknown. Here, we report that the centrosomal microtubule (MT)-binding protein CAP350 localises at adherens junctions in epithelial cells. By two-hybrid screening, we identified a direct interaction of CAP350 with the adhesion protein α-catenin that was further confirmed by co-immunoprecipitation experiments. Block of epithelial cadherin (E-cadherin)-mediated cell-cell adhesion or α-catenin depletion prevented CAP350 localisation at cell-cell junctions. Knocking down junction-located CAP350 inhibited the establishment of an apico-basal array of microtubules and impaired the acquisition of columnar shape in Madin-Darby canine kidney II (MDCKII) cells grown as polarised epithelia. Furthermore, MDCKII cystogenesis was also defective in junctional CAP350-depleted cells. CAP350-depleted MDCKII cysts were smaller and contained either multiple lumens or no lumen. Membrane polarity was not affected, but cortical microtubule bundles did not properly form. Our results indicate that CAP350 may act as an adaptor between adherens junctions and microtubules, thus regulating epithelial differentiation and contributing to the definition of cell architecture. We also uncover a central role of α-catenin in global cytoskeleton remodelling, in which it acts not only on actin but also on MT reorganisation during epithelial morphogenesis. PMID:25764135

  13. A search for H$\\alpha$ emission in high-metallicity damped Lyman-$\\alpha$ systems at $z \\sim 2.4$

    CERN Document Server

    Wang, Wei-Hao; Prochaska, J Xavier

    2015-01-01

    We report on a sensitive search for redshifted H$\\alpha$ line-emission from three high-metallicity damped Ly$\\alpha$ absorbers (DLAs) at $z \\approx 2.4$ with the Near-infrared Integral Field Spectrometer (NIFS) on the Gemini-North telescope, assisted by the ALTtitude conjugate Adaptive optics for the InfraRed (ALTAIR) system with a laser guide star. Within the NIFS field-of-view, $\\approx 3.22" \\times 2.92"$ corresponding to $\\approx 25$ kpc $ \\times 23$ kpc at $z=2.4$, we detect no statistically significant line-emission at the expected redshifted H$\\alpha$ wavelengths. The measured root-mean-square noise fluctuations in $0.4"$ apertures are $1-3\\times10^{-18}$ erg s$^{-1}$ cm$^{-2}$. Our analysis of simulated, compact, line-emitting sources yields stringent limits on the star-formation rates (SFRs) of the three DLAs, $< 2.2$~M$_{\\odot}$ yr$^{-1}$ ($3\\sigma$) for two absorbers, and $< 11$~M$_{\\odot}$ yr$^{-1}$ ($3\\sigma$) for the third, at all impact parameters within $\\approx 12.5$~kpc to the quasar s...

  14. Free-free and H42alpha emission from the dusty starburst within NGC 4945 as observed by ALMA

    CERN Document Server

    Bendo, G J; D'Cruze, M J; Dickinson, C; Fuller, G A; Karim, A

    2016-01-01

    We present observations of the 85.69 GHz continuum emission and H42alpha line emission from the central 30 arcsec within NGC 4945. Both sources of emission originate from nearly identical structures that can be modelled as exponential discs with a scale length of ~2.1 arcsec (or ~40 pc). An analysis of the spectral energy distribution based on combining these data with archival data imply that 84% +/- 10% of the 85.69 GHz continuum emission originates from free-free emission. The electron temperature is 5400 +/- 600 K, which is comparable to what has been measured near the centre of the Milky Way Galaxy. The star formation rate (SFR) based on the H42alpha and 85.69 GHz free-free emission (and using a distance of 3.8 Mpc) is 4.35 +/- 0.25 M/yr. This is consistent with the SFR from the total infrared flux and with previous measurements based on recombination line emission, and it is within a factor of ~2 of SFRs derived from radio data. The Spitzer Space Telescope 24 micron data and Wide-field Infrared Survey E...

  15. X-ray Spectral Study of the extended emission,'the Cap', located 11.6 kpc above the disk of M82

    CERN Document Server

    Tsuru, T G; Hyodo, Y; Matsumoto, H; Koyama, K; Awaki, H; Fujimoto, R; Griffiths, R; Kilbourne, C; Matsushita, K; Mitsuda, K; Ptak, A; Ranalli, P; Yamasaki, N Y; Tsuru, Takeshi Go; Ozawa, Midori; Hyodo, Yoshiaki; Matsumoto, Hironori; Koyama, Katsuji; Awaki, Hisamitsu; Fujimoto, Ryuichi; Griffiths, Richard; Kilbourne, Caroline; Matsushita, Kyoko; Mitsuda, Kazuhisa; Ptak, Andrew; Ranalli, Piero; Yamasaki, Noriko Y.

    2006-01-01

    The extended X-ray emission from 'the Cap' region located 11' (11.6 kpc) above the disk of the starburst galaxy M82 has been observed with Suzaku and XMM-Newton. Owing to the good energy resolution and the large collecting area of the XIS on Suzaku, combined with similar properties of the EPIC instrument on XMM-Newton, we have clearly detected K-shell emission lines from O VII, O VIII, Ne X, Mg XI, Mg XII and the Fe-L complex. Two optically-thin thermal plasma components are required to fit the observed X-ray spectra. We have determined the metal abundances of O, Ne, Mg, Si and Fe in this region for the first time. Their metal abundance ratios agree well with those of metal-poor stars and the model prediction of metals synthesized by type-II supernovae, but they are not consistent with the metallicities of type-Ia supernovae. This result is support for the idea that the origin of the metals in the Cap is type-II supernovae explosions occurring in the starburst regions in the M82 galaxy. We discuss the possibl...

  16. High-spin states in /sup 79/Kr populated by the /sup 78/Se(. cap alpha. ,3n) reaction and interpreted in terms of a quasiparticle-plus-rotor model

    Energy Technology Data Exchange (ETDEWEB)

    Behar, M.; Filevich, A.; Macchiavelli, A.O.; Szybisz, L.; Thieberger, P.

    1982-10-01

    Nuclear states of /sup 79/Kr were studied through the /sup 78/Se(..cap alpha..,3n) reaction at an energy of 45 MeV. Excitation functions, ..gamma..-ray angular distributions and ..gamma..-..gamma.. coincidences were performed. Three bands based on the g.s. (1/2/sup -/), 147.1 keV (5/2/sup -/) and 129.7 keV (7/2/sup +/) states, were identified. Leading order analysis and quasiparticle-plus-rotor model calculations were performed. A good overall agreement was found between the experimental data and the theoretical predictions.

  17. Is the Double Giant Dipole Resonance Process Responsible for Alpha Emission in Ternary Fission?

    Institute of Scientific and Technical Information of China (English)

    HAN Hong-Yin(韩洪银); WAND Yi-Hua(王屹华); G.Mouze

    2001-01-01

    The Monte Carlo program built on the double giant dipole resonance model proposed by Mouze et al. [Nuovo Cimento A 110(1997)1097] was employed to calculate the energy spectrum of alpha particles emitted in the spontaneous ternary fission of 252Cf. It has been found that in the case of the zero orbital angular momentum of alpha particles in the alpha decay of the fragments, the measured alpha spectrum can be reproduced approximately by the model without any adjustable parameter.

  18. A High Fraction of Ly-alpha-Emitters Among Galaxies with Extreme Emission Line Ratios at z ~ 2

    CERN Document Server

    Erb, Dawn K; Steidel, Charles C; Strom, Allison L; Rudie, Gwen C; Trainor, Ryan F; Shapley, Alice E; Reddy, Naveen A

    2016-01-01

    Star-forming galaxies form a sequence in the [OIII]/H-beta vs. [NII]/H-alpha diagnostic diagram, with low metallicity, highly ionized galaxies falling in the upper left corner. Drawing from a large sample of UV-selected star-forming galaxies at z~2 with rest-frame optical nebular emission line measurements from Keck-MOSFIRE, we select the extreme ~5% of the galaxies lying in this upper left corner, requiring log([NII]/H-alpha) = 0.75. These cuts identify galaxies with 12 + log(O/H) 20 A. We compare the equivalent width distribution of a sample of 522 UV-selected galaxies at 2.0alpha equivalent width -1 (-4) A, and only 9% of these galaxies qualify as LAEs. The extreme galaxies typically have lower attenuation at Ly-alpha than those in the comparison sample, and have ~50% lower median oxygen abundances. Both factors are likely to facilitate the escape of Ly-alpha: in less dusty galaxies Ly-alpha photons are l...

  19. On the Lack of Correlation Between Mg II 2796, 2803 Angstrom and Lyman alpha Emission in Lensed Star-Forming Galaxies

    Science.gov (United States)

    Rigby, Jane Rebecca; Bayliss, M. B.; Gladders, M. D.; Sharon, K.; Wuyts, E.; Dahle, H.

    2014-01-01

    We examine the Mg II 2796, 2803 Angstrom, Lyman alpha, and nebular line emission in five bright star-forming galaxies at 1.66 less than z less than 1.91 that have been gravitationally lensed by foreground galaxy clusters. All five galaxies show prominent Mg II emission and absorption in a P Cygni profile. We find no correlation between the equivalent widths of Mg II and Lyman alpha emission. The Mg II emission has a broader range of velocities than do the nebular emission line profiles; the Mg II emission is redshifted with respect to systemic by 100 to 200 km s(exp-1). When present, Lyman alpha is even more redshifted. The reddest components of Mg II and Lyman alpha emission have tails to 500-600 km s(exp-1), implying a strong outflow. The lack of correlation in the Mg II and Lyman alpha equivalent widths, the differing velocity profiles, and the high ratios of Mg II to nebular line fluxes together suggest that the bulk of Mg II emission does not ultimately arise as nebular line emission, but may instead be reprocessed stellar continuum emission.

  20. Optical properties of urban aerosols, aircraft emissions, and heavy-duty diesel trucks using aerosol light extinction measurements by an Aerodyne Cavity Attenuated Phase Shift Particle Extinction Monitor (CAPS PMex)

    Science.gov (United States)

    Freedman, A.; Massoli, P.; Wood, E. C.; Allan, J. D.; Fortner, E.; Yu, Z.; Herndon, S. C.; Miake-Lye, R. C.; Onasch, T. B.

    2010-12-01

    We present results of optical property characterization of ambient particulate during several field deployments where measurements of aerosol light extinction (σep) are obtained using an Aerodyne Cavity Attenuated Phase Shift Particle Extinction Monitor (CAPS PMex). The CAPS PMex is able to provide extinction measurements with 3-σ detection limit of 3 Mm-1 for 1s integration time. The CAPS PMex (630 nm) is integrated in the Aerodyne Research, Inc. (ARI) mobile laboratory where a co-located Multi Angle Absorption Photometer (MAAP) provides particle light absorption coefficient at 632 nm. The combination of the CAPS with the MAAP data allows estimating the single scattering albedo (ω) of the ambient aerosol particles. The ARI mobile laboratory was deployed in winter 2010 at the Chicago O’Hare International Airport to measure gas phase and particulate emissions from different aircraft engines, and during summer 2010 in Oakland, CA, to characterize vehicular gaseous and particulate emissions (mainly exhaust from heavy-duty diesel trucks) from the Caldecott Tunnel. We provide estimates of black carbon emission factors from individual aircraft engines and diesel trucks, in addition to characterizing the optical properties of these ambient samples studying fleet-average emissions for both light-duty passenger vehicles and heavy-duty diesel trucks. Two CAPS PMex instruments (measuring σep at 630 and 532 nm) were also deployed during the CalNex 2010 study (May 14 - June 16) at the CalTech ground site in Pasadena, CA. During the same time, a photo-acoustic spectrometer (PAS, DMT) and an aethalometer instrument (Magee Sci.) measured particle light absorption of submicron aerosol particles from the same sample line as the CAPS PMex monitors. We combine these data to provide multi-wavelength ω trends for the one-month campaign. Our results show the high potential of the CAPS as light weight, compact instrument to perform precise and accurate σep measurements of

  1. Multi-epoch Spectroscopy of Dwarf Galaxies with AGN Signatures: Identifying Sources with Persistent Broad H-alpha Emission

    CERN Document Server

    Baldassare, Vivienne F; Gallo, Elena; Greene, Jenny E; Graur, Or; Geha, Marla; Hainline, Kevin; Carroll, Christopher M; Hickox, Ryan C

    2016-01-01

    We use time-domain optical spectroscopy to distinguish between broad emission lines powered by accreting black holes (BHs) or stellar processes (i.e., supernovae) for 16 galaxies identified as AGN candidates by Reines et al. (2013). 14 of these have star-formation--dominated narrow-line emission ratios, one is a narrow-line AGN, and the last is a star-forming--AGN composite. We find that broad H$\\alpha$ emission has faded for 11/16 targets, based on spectra taken with the Magellan Echellette Spectrograph (MagE), the Dual Imaging Spectrograph, and the Ohio State Multi-Object Spectrograph with baselines ranging from 5 to 14 years. The 11 faded systems all have narrow-line ratios consistent with recent star formation, suggesting the broad emission for those targets was produced by a transient stellar process. The two objects with narrow-line AGN signatures (RGG 9 and RGG 119) have persistent broad H$\\alpha$ emission consistent with previous SDSS observations. The final three star-forming objects are classified a...

  2. Lyman-alpha Emission from a Luminous z=8.68 Galaxy: Implications for Galaxies as Tracers of Cosmic Reionization

    CERN Document Server

    Zitrin, Adi; Belli, Sirio; Bouwens, Rychard; Ellis, Richard S; Roberts-Borsani, Guido; Stark, Daniel P; Oesch, Pascal A; Smit, Renske

    2015-01-01

    We report the discovery of Lyman-alpha emission (Ly$\\alpha$) in the bright galaxy EGSY-2008532660 (hereafter EGSY8p7) using the MOSFIRE spectrograph at the Keck Observatory. First reported by Roberts-Borsani et al. (2015), it was selected for spectroscopic observations because of its photometric redshift ($z_{phot}=8.57^{+0.22}_{-0.43}$), apparent brightness (H$_{160}=25.26\\pm0.09$) and red Spitzer/IRAC [3.6]-[4.5] color indicative of contamination by strong oxygen emission in the [4.5] band. With a total integration of $\\sim4.3$ hours, our data reveal an emission line at $\\simeq11776$ {\\AA} which we argue is likely Ly$\\alpha$ at a redshift $z_{spec}=8.68$, in good agreement with the photometric estimate. The line was detected independently on two nights using different slit orientations and its detection significance is $\\sim7.5\\sigma$. An overlapping sky line contributes significantly to the uncertainty on the total line flux but not the overall significance. By direct addition and a Gaussian fit, we estima...

  3. A Randomized Multicentre Phase II Trial Comparing Adjuvant Therapy in Patients with Interferon Alpha-2b and 5-FU Alone or in Combination with Either External Radiation Treatment and Cisplatin (CapRI or Radiation alone regarding Event-Free Survival – CapRI-2

    Directory of Open Access Journals (Sweden)

    Friess Helmut

    2009-05-01

    Full Text Available Abstract Background The 5-year survival of patients with resected pancreatic adenocarcinoma is still unsatisfying. The ESPAC-1 and the CONKO 001 trial proofed that adjuvant chemotherapy improves 5-year survival significantly from approximately 14% to 21%. In parallel, investigators from the Virginia Mason Clinic reported a 5-year survival rate of 55% in a phase II trial evaluating a combination of adjuvant chemotherapy, immunotherapy and external beam radiation (CapRI-scheme. Two other groups confirmed in phase II trials these results to a certain extent. However, these groups reported severe gastrointestinal toxicity (up to 93% grade 3 or 4 toxicity. In a randomized controlled phase III trial, called CapRI, 110 patients were enrolled from 2004 to 2007 in Germany and Italy to check for reproducibility. Interestingly, much less gastrointestinal toxicity was observed. However, dose-reduction due to haematological side effects had to be performed in nearly all patients. First clinical results are expected for the end of 2009. Methods/Design CapRI-2 is an open, controlled, prospective, randomized, multicentre phase II trial with three parallel arms. A de-escalation of the CapRI-scheme will be tested in two different modifications. Patients in study arm A will be treated as outpatients with the complete CapRI-scheme consisting of cisplatin, Interferon alpha-2b and external beam radiation and three cycles of 5-fluorouracil continuous infusion. In study arm B the first de-escalation will be realised by omitting cisplatin. Next, patients in study arm C will additionally not receive external beam radiation. A total of 135 patients with pathologically confirmed R0 or R1 resected pancreatic adenocarcinoma are planned to be enrolled. Primary endpoint is the comparison of the treatment groups with respect to six-month event-free-survival. An event is defined as grade 3 or grade 4 toxicity, objective tumour recurrence, or death. Discussion The aim of this

  4. Cross-border electricity market effects due to price caps in an emission trading system: An agent-based approach

    NARCIS (Netherlands)

    Richstein, J.C.; Chappin, E.J.L.; De Vries, L.J.

    2014-01-01

    The recent low CO2 prices in the European Union Emission Trading Scheme (EU ETS) have triggered a discussion whether the EU ETS needs to be adjusted. We study the effects of CO2 price floors and a price ceiling on the dynamic investment pathway of two interlinked electricity markets (loosely based o

  5. Pulsar Polar Cap Heating and Surface Thermal X-Ray Emission. II. Inverse Compton Radiation Pair Fronts

    CERN Document Server

    Muslimov, A G; Muslimov, Alice K. Harding & Alexander

    2002-01-01

    We investigate the production of electron-positron pairs by inverse Compton scattered (ICS) photons above a pulsar polar cap (PC) and surface heating by returning positrons. This paper is a continuation of our self-consistent treatment of acceleration, pair dynamics and electric field screening above pulsar PCs. We calculate the altitude of the inverse Compton pair formation fronts, the flux of returning positrons and present the heating efficiencies and X-ray luminosities. We revise pulsar death lines implying cessation of pair formation, and present them in surface magnetic field-period space. We find that virtually all known radio pulsars are capable of producing pairs by resonant and non-resonant ICS photons radiated by particles accelerated above the PC in a pure star-centered dipole field, so that our ICS pair death line coincides with empirical radio pulsar death. Our calculations show that ICS pairs are able to screen the accelerating electric field only for high neutron star surface temperatures and ...

  6. Discovery of H-alpha Emission from the Close Companion Inside the Gap of Transitional Disk HD142527

    CERN Document Server

    Close, L M; Males, J R; Puglisi, A; Xompero, M; Apai, D; Najita, J; Weinberger, A J; Morzinski, K; Rodigas, T J; Hinz, P; Bailey, V; Briguglio, R

    2014-01-01

    We utilized the new high-order 585 actuator Magellan Adaptive Optics system (MagAO) to obtain very high-resolution visible light images of HD142527 with MagAO's VisAO science camera. In the median seeing conditions of the 6.5m Magellan telescope (0.5-0.7"), we find MagAO delivers 24-19% Strehl at H-alpha (0.656 microns). We detect a faint companion (HD142527B) embedded in this young transitional disk system at just 86.3+/-1.9 mas (~12 AU) from the star. The companion is detected in both H-alpha and a continuum filter (Delta_mag=6.33+/-0.20 mag at H-alpha and 7.50+/-0.25 mag in the continuum filter). This provides confirmation of the tentative companion discovered by Biller and co-workers with sparse aperture masking at the 8m VLT. The H-alpha emission from the ~0.25 solar mass companion (EW=180 Angstroms) implies a mass accretion rate of ~5.9x10^-10 Msun/yr, and a total accretion luminosity of 1.2% Lsun. Assuming a similar accretion rate, we estimate that a 1 Jupiter mass gas giant could have considerably bet...

  7. FUV Irradiated Disk Atmospheres: Ly$\\alpha$ and the Origin of Hot H$_2$ Emission

    CERN Document Server

    Ádámkovics, Máté; Glassgold, Alfred E

    2015-01-01

    Protoplanetary disks are strongly irradiated by a stellar FUV spectrum that is dominated by Ly$\\alpha$ photons. We investigate the impact of stellar Ly$\\alpha$ irradiation on the terrestrial planet region of disks ($\\lesssim 1$AU) using an updated thermal-chemical model of a disk atmosphere irradiated by stellar FUV and X-rays. The radiative transfer of Ly$\\alpha$ is implemented in a simple approach that includes scattering by H I and absorption by molecules and dust. Because of their non-radial propagation path, scattered Ly$\\alpha$ photons deposit their energy deeper in the disk atmosphere than the radially propagating FUV continuum photons. We find that Ly$\\alpha$ has a significant impact on the thermal structure of the atmosphere. Photochemical heating produced by scattered Ly$\\alpha$ photons interacting with water vapor and OH leads to a layer of hot (1500 - 2500 K) molecular gas. The temperature in the layer is high enough to thermally excite the H$_2$ to vibrational levels from which they can be fluore...

  8. A cosmic web filament revealed in Lyman-alpha emission around a luminous high-redshift quasar

    CERN Document Server

    Cantalupo, Sebastiano; Prochaska, J Xavier; Hennawi, Joseph F; Madau, Piero

    2014-01-01

    Simulations of structure formation in the Universe predict that galaxies are embedded in a "cosmic web", where the majority of baryons reside as rarefied and highly ionized gas. This material has been studied for decades in absorption against background sources, but the sparseness of these inherently one-dimensional probes preclude direct constraints on the three-dimensional morphology of the underlying web. Here we report observations of a cosmic web filament in Lyman-alpha emission, discovered during a survey for cosmic gas fluorescently "illuminated" by bright quasars at z=2.3. With a projected size of approximately 460 physical kpc, the Lyman-alpha emission surrounding the radio-quiet quasar UM287 extends well beyond the virial radius of any plausible associated dark matter halo. The estimated cold gas mass of the nebula from the observed emission is at least ten times larger than what is typically found by cosmological simulations, suggesting that a population of intergalactic gas clumps with sub-kpc siz...

  9. The BOSS Emission-Line Lens Survey. III. : Strong Lensing of Ly$\\alpha$ Emitters by Individual Galaxies

    CERN Document Server

    Shu, Yiping; Kochanek, Christopher S; Oguri, Masamune; Perez-Fournon, Ismael; Zheng, Zheng; Mao, Shude; Montero-Dorta, Antonio D; Brownstein, Joel R; Marques-Chaves, Rui; Menard, Brice

    2016-01-01

    We introduce the BOSS Emission-Line Lens Survey (BELLS) GALaxy-Ly$\\alpha$ EmitteR sYstems (BELLS GALLERY) Survey, which is a Hubble Space Telescope program to image a sample of galaxy-scale strong gravitational lens candidate systems with high-redshift Ly$\\alpha$ emitters (LAEs) as the background sources. The goal of the BELLS GALLERY Survey is to illuminate dark substructures in galaxy-scale halos by exploiting the small-scale clumpiness of rest-frame far-UV emission in lensed LAEs, and to thereby constrain the slope and normalization of the substructure mass function. In this paper, we describe in detail the spectroscopic strong-lens selection technique, which is based on methods adopted in the previous Sloan Lens ACS (SLACS) Survey, BOSS Emission-Line Lens Survey, and SLACS for the Masses Survey. We present the BELLS GALLERY sample of the 21 highest-quality galaxy-LAE candidates selected from $\\approx 1.4 \\times 10^6$ galaxy spectra in the Baryon Oscillation Spectroscopic Survey (BOSS) of the Sloan Digital...

  10. Resolving the Composite Fe K-alpha Emission Line in the Galactic Black Hole Cygnus X-1 with Chandra

    CERN Document Server

    Miller, J M; Wijnands, R; Remillard, R A; Wojdowski, P S; Schulz, N S; Matteo, T D; Marshall, H L; Canizares, C R; Pooley, D; Lewin, W H G

    2002-01-01

    We observed the Galactic black hole Cygnus X-1 with the Chandra High Energy Transmission Grating Spectrometer for 30 kiloseconds on 4 January, 2001. The source was in an intermediate state, with a flux that was approximately twice that commonly observed in its persistent low/hard state. Our best-fit model for the X-ray spectrum includes narrow Gaussian emission line (E = 6.415 +/- 0.007 keV, FWHM = 80 (+28, -19) eV, W = 16 (+3, -2) eV) and broad line (E = 5.82 (+0.06, -0.07) keV, FWHM = 1.9 (+0.5, -0.3) keV, W = 140 (+70, -40) eV) components, and a smeared edge at 7.3 +/- 0.2 keV (tau ~ 1.0). The broad line profile is not as strongly skewed as those observed in some Seyfert galaxies. We interpret these features in terms of an accretion disk with irradiation of the inner disk producing a broad Fe K-alpha emission line and edge, and irradiation of the outer disk producing a narrow Fe K-alpha emission line. The broad line is likely shaped predominantly by Doppler shifts and gravitational effects, and to a lesser...

  11. Cytochrome P450c17 (steroid 17. cap alpha. -hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues

    Energy Technology Data Exchange (ETDEWEB)

    Chung, B.; Picado-Leonard, J.; Haniu, M.; Bienkowski, M.; Hall, P.F.; Shively, J.E.; Miller, W.L.

    1987-01-01

    P450c17 is the single enzyme mediating both 17..cap alpha..-hydroxylase (steroid 17..cap alpha..-monooxygenase, EC 1.14.99.9) and 17,20 lyase activities in the synthesis of steroid hormones. It has been suggested that different P450c17 isozymes mediate these activities in the adrenal gland and testis. The authors sequenced 423 of the 509 amino acids (83%) of the porcine adrenal enzyme; based on this partial sequence, a 128-fold degenerate 17-mer was synthesized and used to screen a porcine adrenal cDNA library. This yielded a 380-base cloned cDNA, which in turn was used to isolate several human adrenal cDNAs. The longest of these, lambda hac 17-2, is 1754 base pairs long and includes the full-length coding region, the complete 3'-untranslated region, and 41 bases of the 5'-untranslated region. This cDNA encodes a protein of 508 amino acids having a predicted molecular weight of 57,379.82. High-stringency screening of a human testicular cDNA library yielded a partial clone containing 1303 identical bases. RNA gel blots and nuclease S1-protection experiments confirm that the adrenal and testicular P450c17 mRNAs are indistinguishable. These data indicate that the testis possesses a P450c17 identical to that in the adrenal. The human amino acid sequence is 66.7% homologous to the corresponding regions of the porcine sequence, and the human cDNA and amino acid sequences are 80.1 and 70.3% homologous, respectively, to bovine adrenal P450c17 cDNA. Both comparisons indicate that a central region comprising amino acid residues 160-268 is hypervariable among these species of P450c17.

  12. pH-dependent optical properties of N-acetyl-L-cysteine-capped ZnSe(S) nanocrystals with intense/stable emissions

    Science.gov (United States)

    Soheyli, Ehsan; Sahraei, Reza; Nabiyouni, Gholamreza

    2017-03-01

    In the present study, a series of aqueous-based ZnSe(S) nanocrystals (NCs) was prepared at different solution pH ranging from 8 to 11.9, and using N-acetyl-L-cysteine (NAC) as capping agent. In addition to zinc blende structure, the X-ray diffraction studies demonstrated the quantum size regime of the ZnSe(S) NCs. To gain further insight toward the influence of the quantum confinement and pH values on optical properties of the as-prepared NCs, their UV-visible absorption and photoluminescence spectra were systematically analyzed. The absorption spectra experienced a red shift from 340 to 382 nm as the pH increased from 8.0 to 11.9, indicating the growth of the as-prepared ZnSe(S) NCs. The emission spectra also show the obvious red shift and the relative area of excitonic to trap emission, firstly increases from pH = 8.0 to 10.7, and then decreases by further increasing of the solution pH. The initial behavior might be due to the improved surface passivation of the trap dangling states by better deprotonation of thiol groups in NAC, whereas at pH >10.7, the faster growth rate of the ZnSe(s) NCs may lead to the formation of many defect sites. All of these phenomena were combined in the scheme which displays the effect of quantum confinement and solution pH on variation of the excitonic and trap-related emissions.

  13. Death cap

    DEFF Research Database (Denmark)

    Rudbæk, Torsten R; Kofoed, Pernille Bouteloup; Bove, Jeppe

    2014-01-01

    Death cap (Amanita phalloides) is commonly found and is one of the five most toxic fungi in Denmark. Toxicity is due to amatoxin, and poisoning is a serious medical condition, causing organ failure with potential fatal outcome. Acknowledgement and clarification of exposure, symptomatic and focused...

  14. Predicting the Redshift 2 H-Alpha Luminosity Function Using [OIII] Emission Line Galaxies

    Science.gov (United States)

    Mehta, Vihang; Scarlata, Claudia; Colbert, James W.; Dai, Y. S.; Dressler, Alan; Henry, Alaina; Malkan, Matt; Rafelski, Marc; Siana, Brian; Teplitz, Harry I.; Bagley, Micaela; Beck, Melanie; Ross, Nathaniel R.; Rutkowski, Michael; Wang, Yun

    2015-01-01

    Upcoming space-based surveys such as Euclid and WFIRST-AFTA plan to measure Baryonic Acoustic Oscillations (BAOs) in order to study dark energy. These surveys will use IR slitless grism spectroscopy to measure redshifts of a large number of galaxies over a significant redshift range. In this paper, we use the WFC3 Infrared Spectroscopic Parallel Survey (WISP) to estimate the expected number of H-alpha emitters observable by these future surveys. WISP is an ongoing Hubble Space Telescope slitless spectroscopic survey, covering the 0.8 - 1.65 micrometers wavelength range and allowing the detection of H-alpha emitters up to z approximately equal to 1.5 and [OIII] emitters to z approximately equal to 2.3. We derive the H-alpha-[OIII] bivariate line luminosity function for WISP galaxies at z approximately equal to 1 using a maximum likelihood estimator that properly accounts for uncertainties in line luminosity measurement, and demonstrate how it can be used to derive the H-alpha luminosity function from exclusively fitting [OIII] data. Using the z approximately equal to 2 [OIII] line luminosity function, and assuming that the relation between H-alpha and [OIII] luminosity does not change significantly over the redshift range, we predict the H-alpha number counts at z approximately equal to 2 - the upper end of the redshift range of interest for the future surveys. For the redshift range 0.7 less than z less than 2, we expect approximately 3000 galaxies per sq deg for a flux limit of 3 x 10(exp -16) ergs per sec per sq cm (the proposed depth of Euclid galaxy redshift survey) and approximately 20,000 galaxies per sq deg for a flux limit of approximately 10(exp -16) ergs per sec per sq cm (the baseline depth of WFIRST galaxy redshift survey).

  15. Modelling and simulation of large-scale polarized dust emission over the southern Galactic cap using the GASS HI data

    CERN Document Server

    Ghosh, Tuhin; Martin, Peter G; Bracco, Andrea; Vansyngel, Flavien; Aumont, Jonathan; Bock, Jamie; Doré, Olivier; Haud, Urmas; Kalberla, Peter M W; Serra, Paolo

    2016-01-01

    The Planck survey has quantified polarized Galactic foregrounds and established that they are a main limiting factor in the quest for the cosmic microwave background (CMB) B-mode signal induced by primordial gravitational waves during cosmic inflation. The necessity of achieving an accurate separation of the Galactic foregrounds therefore binds the search for the signal from cosmic inflation to our understanding of the magnetized interstellar medium (ISM). The two most relevant observational results coming out of Planck data analysis are the line of sight depolarization due to the fluctuations of the Galactic magnetic field orientation and the alignment of the dust filamentary structures with the magnetic field at high Galactic latitude. Furthermore, Planck and HI emission data in combination indicate that most of the dust filamentary structures are present in the cold neutral medium. The goal of this paper is to test whether together these salient observational results can account fully for the statistical p...

  16. The emission probabilities of long range alpha particles from even-even 244-252Cm isotopes

    CERN Document Server

    Santhosh, K P; Priyanka, B

    2014-01-01

    The alpha accompanied cold ternary fission of even-even 244Cm, 246Cm, 248Cm, 250Cm and 252Cm isotopes have been studied by taking the interacting barrier as the sum of Coulomb and proximity potential with the fragments in equatorial configuration. The favorable fragment combinations are obtained from the cold reaction valley plot and by calculating the relative yield for the charge minimized fragments. In the alpha accompanied ternary fission of 244Cm isotope, the highest yield is found for the fragment combination 110Ru+4He+130Sn, which possess near doubly magic nuclei 130Sn. For the ternary fission of 246Cm, 248Cm, 250Cm and 252Cm isotopes with 4He as light charged particle, the highest yield is obtained for the fragment combination with doubly magic nuclei 132Sn as the heavier fragment. The emission probabilities and kinetic energies of long range alpha particle have been computed for the 242,244,246,248Cm isotopes and are found to be in good agreement with the experimental data. The relative yields for th...

  17. Can a many-nucleon structure be visible in bremsstrahlung emission during $\\alpha$ decay?

    CERN Document Server

    Maydanyuk, Sergei P; Zou, Li-Ping

    2015-01-01

    We analyze if the nucleon structure of the $\\alpha$ decaying nucleus can be visible in the experimental bremsstrahlung spectra of the emitted photons which accompany such a decay. We develop a new formalism of the bremsstrahlung model taking into account distribution of nucleons in the $\\alpha$ decaying nuclear system. We conclude the following: (1) After inclusion of the nucleon structure into the model the calculated bremsstrahlung spectrum is changed very slowly for a majority of the $\\alpha$ decaying nuclei. However, we have observed that visible changes really exist for the $^{106}{\\rm Te}$ nucleus ($Q_{\\alpha}=4.29$ MeV, $T_{1/2}$=70 mks) even for the energy of the emitted photons up to 1 MeV. This nucleus is a good candidate for future experimental study of this task. (2) Inclusion of the nucleon structure into the model increases the bremsstrahlung probability of the emitted photons. (3) We find the following tendencies for obtaining the nuclei, which have bremsstrahlung spectra more sensitive to the ...

  18. Alpha-particle emissivity screening of materials used for semiconductor manufacturing

    Science.gov (United States)

    Gordon, Michael; Rodbell, Kenneth

    2015-03-01

    Single-Event Upsets (SEU's) in semiconductor memory and logic devices continue to be a reliability issue in modern CMOS devices. SEU's result from deposited charge in the Si devices caused by the passage of ionizing radiation. With technology scaling, the device area decreases, but the critical charge required to flip bits decreases as well. The interplay between both determines how the SEU rate scales with shrinking device geometries and dimensions. In order to minimize the alpha-particle component of SEU, the radiation in the device environment has to be at the Ultra-Low Alpha (ULA) activity levels, e.g. less than 2 α/khr-cm2. Most detectors have background levels that are significantly larger than that level which makes making these measurements difficult and time consuming. A new class of alpha particle detector, utilizing pulse shape discrimination, is now available which allows one to make measurements quickly with ultra-low detector background. This talk will discuss what is involved in making alpha particle measurements of materials in the ULA activity levels, in terms of calibration, radon adsorption mitigation, the time required for obtaining reasonable statistics and comparisons to other detectors.

  19. Phase III trial of postoperative cisplatin, interferon alpha-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma – CapRI: study protocol [ISRCTN62866759

    Directory of Open Access Journals (Sweden)

    Schmitz-Winnenthal H

    2005-04-01

    Full Text Available Abstract After surgical intervention with curative intention in specialised centres the five-year survival of patients with carcinoma of the exocrine pancreas is only 15%. The ESPAC-1 trial showed an increased five-year survival of 21% achieved with adjuvant chemotherapy. Investigators from the Virginia Mason Clinic have reported a 5-year survival rate of 55% in a phase II trial evaluating adjuvant chemotherapy, immunotherapy and external-beam radiation. Design The CapRI study is an open, controlled, prospective, randomised multi-centre phase III trial. Patients in study arm A will be treated as outpatients with 5-Fluorouracil; Cisplatin and 3 million units Interferon alpha-2b for 5 1/2 weeks combined with external beam radiation. After chemo-radiation the patients receive continuous 5-FU infusions for two more cycles. Patients in study arm B will be treated as outpatients with intravenous bolus injections of folinic acid, followed by intravenous bolus injections of 5-FU given on 5 consecutive days every 28 days for 6 cycles. A total of 110 patients with specimen-proven R0 or R1 resected pancreatic adenocarcinoma will be enrolled. An interim analysis for patient safety reasons will be done one year after start of recruitment. Evaluation of the primary endpoint will be performed two years after the last patients' enrolment. Discussion The aim of this study is to evaluate the overall survival period attained by chemo-radiotherapy including interferon alpha 2b administration with adjuvant chemotherapy. The influence of interferon alpha on the effectiveness of the patients' chemoradiation regimen, the toxicity, the disease-free interval and the quality of life are analysed. Different factors are tested in terms of their potential role as predictive markers.

  20. The Grism Lens-Amplified Survey from Space (GLASS). III. A census of Ly\\alpha\\ Emission at $z\\gtrsim$7 from HST Spectroscopy

    CERN Document Server

    Schmidt, K B; Bradač, M; Vulcani, B; Huang, K -H; Hoag, A; Maseda, M; Guaita, L; Pentericci, L; Brammer, G B; Dijkstra, M; Dressler, A; Fontana, A; Henry, A L; Jones, T A; Mason, C; Trenti, M; Wang, X

    2015-01-01

    [abbreviated] We present a census of Ly\\alpha\\ emission at $z\\gtrsim7$ utilizing deep near infrared HST grism spectroscopy from the first six completed clusters of the Grism Lens-Amplified Survey from Space (GLASS). In 24/159 photometrically selected galaxies we detect emission lines consistent with Ly\\alpha\\ in the GLASS spectra. Based on the distribution of signal-to-noise ratios and on simulations we expect the completeness and the purity of the sample to be 40-100% and 60-90%, respectively. For the objects without detected emission lines we show that the observed (not corrected for lensing magnification) 1$\\sigma$ flux limits reaches $5\\times10^{-18}$erg/s/cm$^{2}$ per position angle over the full wavelength range of GLASS (0.8-1.7$\\mu$m). Based on the conditional probability of Ly\\alpha\\ emission measured from the ground at $z\\sim7$ we would have expected 12-18 Ly\\alpha\\ emitters. This is consistent with the number of detections, within the uncertainties, confirming the drop in Ly\\alpha\\ emission with re...

  1. Apical cap

    Energy Technology Data Exchange (ETDEWEB)

    McLoud, T.C.; Isler, R.J.; Novelline, R.A.; Putman, C.E.; Simeone, J.; Stark, P.

    1981-08-01

    Apical caps, either unilateral or bilateral, are a common feature of advancing age and are usually the result of subpleural scarring unassociated with other diseases. Pancoast (superior sulcus) tumors are a well recognized cause of unilateral asymmetric apical density. Other lesions arising in the lung, pleura, or extrapleural space may produce unilateral or bilateral apical caps. These include: (1) inflammatory: tuberculosis and extrapleural abscesses extending from the neck; (2) post radiation fibrosis after mantle therapy for Hodgkin disease or supraclavicular radiation in the treatment of breast carcinoma; (3) neoplasm: lymphoma extending from the neck or mediastinum, superior sulcus bronchogenic carcinoma, and metastases; (4) traumatic: extrapleural dissection of blood from a ruptured aorta, fractures of the ribs or spine, or hemorrhage due to subclavian line placement; (5) vascular: coarctation of the aorta with dilated collaterals over the apex, fistula between the subclavian artery and vein; and (6) miscellaneous: mediastinal lipomatosis with subcostal fat extending over the apices.

  2. Can the Regulation of Environmental Pollution Emission Cap Reduce Enterprises Pollution Emissions Effectively?-An Analysis on Dynamic Model of Game between Government and Enterprises%环境污染排放限额制度能有效降低企业污染排放吗?--一个政企动态博弈模型分析

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    This paper, aiming at the practical process characteristics of the regulation of environmental pollution emission cap, builds a dynamic model of game between government and enterprises under the regulation of environmental pollution emission cap,studies the dynamic equilibrium relationship between government expected social costs and enterprises cutting pollution costs in different contexts,and reasonably explains why it is difficult to reduce enterprises pollution emissions effec⁃tively under the regulation of environmental pollution emission cap. The study proves that enterprises would make use of their information advantages to ease the cap whether the government adopts a soft or rigid cap for the implementation of regulation of environmental pollution emission cap,which can not reduce enterprises pollution emissions effectively.%文章针对环境污染排放限额制度这一环境规制措施的实践过程特点,构建了环境污染排放限额制度下的政府与企业动态博弈模型,研究分析不同情形下的政府期望社会成本与企业削减污染成本的动态平衡关系,给予实施环境污染排放限额制度为何难以有效降低企业污染排放合理解释。文章研究证明,政府无论是采取软性还是硬性限额方式实施环境污染排放限额制度,企业均可利用其信息优势争取到宽松的允许污染排放限额,并不能有效地降低企业污染排放。

  3. Summer season variability of the north residual cap of Mars as observed by the Mars Global Surveyor Thermal Emission Spectrometer (MGS-TES)

    Science.gov (United States)

    Calvin, W.M.; Titus, T.N.

    2008-01-01

    Previous observations have noted the change in albedo in a number of North Pole bright outliers and in the distribution of bright ice deposits between Mariner 9, Viking, and Mars Global Surveyor (MGS) data sets. Changes over the summer season as well as between regions at the same season (Ls) in different years have been observed. We used the bolometric albedo and brightness temperature channels of the Thermal Emission Spectrometer (TES) on the MGS spacecraft to monitor north polar residual ice cap variations between Mars years and within the summer season for three northern Martian summers between July 1999 and April 2003. Large-scale brightness variations are observed in four general areas: (1) the patchy outlying frost deposits from 90 to 270??E, 75 to 80??N; (2) the large "tail" below the Chasma Boreale and its associated plateau from 315 to 45??E, 80 to 85??N, that we call the "Boreale Tongue" and in Hyperboreae Undae; (3) the troughed terrain in the region from 0 to 120??E longitude (the lower right on a polar stereographic projection) we have called "Shackleton's Grooves" and (4) the unit mapped as residual ice in Olympia Planitia. We also note two areas which seem to persist as cool and bright throughout the summer and between Mars years. One is at the "source" of Chasma Boreale (???15??E, 85??N) dubbed "McMurdo", and the "Cool and Bright Anomaly (CABA)" noted by Kieffer and Titus 2001. TES Mapping of Mars' north seasonal cap. Icarus 154, 162-180] at ???330??E, 87??N called here "Vostok". Overall defrosting occurs early in the summer as the temperatures rise and then after the peak temperatures are reached (Ls???110) higher elevations and outlier bright deposits cold trap and re-accumulate new frost. Persistent bright areas are associated with either higher elevations or higher background albedos suggesting complex feedback mechanisms including cold-trapping of frost due to albedo and elevation effects, as well as influence of mesoscale atmospheric dynamics

  4. Tuning the work function of randomly oriented ZnO nanostructures by capping with faceted Au nanostructure and oxygen defects: enhanced field emission experiments and DFT studies.

    Science.gov (United States)

    Ghosh, Arnab; Guha, Puspendu; Thapa, Ranjit; Selvaraj, Sinthika; Kumar, Mohit; Rakshit, Bipul; Dash, Tapan; Bar, Rajshekhar; Ray, Samit K; Satyam, Parlapalli Venkata

    2016-03-29

    The lowering of the work function (Φ) can lead to a better field emission (FE) behavior at lower threshold fields. We report on enhanced FE from randomly oriented and faceted Au-capped ZnO hetero-nanostructures (HNs) having more oxygen defects. Large-area arrays of non-aligned, faceted Au-capped ZnO HNs, such as nanowires (NWs) and triangular nanoflakes (TNFs) are grown using the chemical vapor deposition (CVD) method. Enhanced FE properties from the TNF sample resulted in a turn-on field as low as 0.52 V μm(-1) at a current density of 0.1 mA cm(-2) and a field enhancement factor (β) as high as ≈5.16 × 10(5). Under similar experimental conditions, drawing the same current density from an NW specimen needs a higher turn-on field (0.86 V μm(-1)) and to exhibit nearly four times less field enhancement factor compared to the TNFs samples. X-ray photoelectron spectroscopy (XPS) and photoluminescence (PL) measurements confirm the presence of more oxygen defects in the TNF samples compared to the NW samples. Kelvin probe force microscopy (KPFM) measurements show the average local work function to be 4.70 ± 0.1 eV for the TNF sample, which is ≈ 0.34 eV lower than the NW sample. Using density functional theory (DFT) calculations, the estimated Φ values are found to be 4.98 eV for ZnO(0001), 4.17 eV for Au(001)/ZnO(0001) and 3.91 eV for Au(001)/Ovac-ZnO(0001) surfaces. The DFT results are qualitatively in agreement with our experimental results. The presence of Au nanostructures on top of O-deficient and sharp-tipped TNFs results in enhanced FE performance following their reduced tunneling barrier via pinning of effective Φ.

  5. Correlated emission of three {alpha}-particles in the {beta}-decay of {sup 12}N

    Energy Technology Data Exchange (ETDEWEB)

    Fynbo, H.O.U.; Oinonen, M.; Weissman, L. [EP Division, CERN, CH-1211 Geneve 23 (Switzerland); Prezado, Y.; Borge, M.J.G.; Tengblad, O. [Instituto Estructura de la Materia, CSIC, Serrano 113bis, E-28006 Madrid (Spain); Aeystoe, J.; Dendooven, P.; Huang, W.; Huikari, J.; Jones, P.; Wang, Y. [Department of Physics, University of Jyvaeskylae, FIN-40351 Jyvaeskylae (Finland); Bergmann, U.C.; Jeppesen, H.; Riisager, K.; Vogelius, I.S. [Institut for Fysik og Astronomi, Aarhus Universitet, DK-8000 Aarhus C (Denmark); Jonson, B.; Meister, M.; Nyman, G. [Experimentell Fysik, Chalmers Tekniska Hoegskola, S-412 96 Goeteborg (Sweden); Rolander, K.W. [Fysiska Institutionen, Stockholms Universitet, Box 6730, S-113 85 Stockholm (Sweden)

    2002-10-01

    The {beta}-decay of {sup 12}N is used to populate {alpha}-emitting excited states in {sup 12}C. The {alpha}-particles from the break-up of both the 10.3 MeV and 12.71 MeV states were measured in coincidence with an efficient detector setup consisting of two double-sided Si strip detectors. The break-up of the 12.71 MeV 1{sup +} state is an interesting testing ground for the different descriptions of multi-particle break-up, whereas the properties of the 10.3 MeV state, which under some astrophysical conditions is relevant for the production of {sup 12}C in stars, are poorly known. First results from the analysis of the data is presented and compared with Monte Carlo simulations. (orig.)

  6. H-alpha Variability in PTFO8-8695 and the Possible Direct Detection of Emission from a 2 Million Year Old Evaporating Hot Jupiter

    CERN Document Server

    Johns-Krull, Christopher M; McLane, Jacob N; Ciardi, David R; van Eyken, Julian C; Chen, Wei; Stauffer, John R; Beichman, Charles A; Frazier, Sarah A; Boden, Andrew F; Morales-Calderon, Maria; Rebull, Luisa M

    2016-01-01

    We use high time cadence, high spectral resolution optical observations to detect excess H-alpha emission from the 2 - 3 Myr old weak lined T Tauri star PTFO8-8695. This excess emission appears to move in velocity as expected if it were produced by the suspected planetary companion to this young star. The excess emission is not always present, but when it is, the predicted velocity motion is often observed. We have considered the possibility that the observed excess emission is produced by stellar activity (flares), accretion from a disk, or a planetary companion; we find the planetary companion to be the most likely explanation. If this is the case, the strength of the H-alpha line indicates that the emission comes from an extended volume around the planet, likely fed by mass loss from the planet which is expected to be overflowing its Roche lobe.

  7. Mammalian CAP interacts with CAP, CAP2, and actin.

    Science.gov (United States)

    Hubberstey, A; Yu, G; Loewith, R; Lakusta, C; Young, D

    1996-06-01

    We previously identified human CAP, a homolog of the yeast adenylyl cyclase-associated protein. Previous studies suggest that the N-terminal and C-terminal domains of CAP have distinct functions. We have explored the interactions of human CAP with various proteins. First, by performing yeast two-hybrid screens, we have identified peptides from several proteins that interact with the C-terminal and/or the N-terminal domains of human CAP. These peptides include regions derived from CAP and BAT3, a protein with unknown function. We have further shown that MBP fusions with these peptides can associate in vitro with the N-terminal or C-terminal domains of CAP fused to GST. Our observations indicate that CAP contains regions in both the N-terminal and C-terminal domains that are capable of interacting with each other or with themselves. Furthermore, we found that myc-epitope-tagged CAP coimmunoprecipitates with HA-epitope-tagged CAP from either yeast or mammalian cell extracts. Similar results demonstrate that human CAP can also interact with human CAP2. We also show that human CAP interacts with actin, both by the yeast two-hybrid test and by coimmunoprecipitation of epitope-tagged CAP from yeast or mammalian cell extracts. This interaction requires the C-terminal domain of CAP, but not the N-terminal domain. Thus CAP appears to be capable of interacting in vivo with other CAP molecules, CAP2, and actin. We also show that actin co-immunoprecipitates with HA-CAP2 from mammalian cell extracts.

  8. Orientation of the linear polarization plane of H-alpha emission in prominences

    CERN Document Server

    Suyunova, E Z; Osokin, A R

    2015-01-01

    2D distributions of deviations of the polarization plane from the direction tangential to the solar limb (angle \\chi) and the sign of \\chi are presented for H{\\alpha} prominences of March 29, 2006. The obtained values of \\chi are in agreement with non-eclipse coronagraphic measurements and indicate the existence of longitudinal magnetic fields. The 2D distributions of the sign of \\chi show the existence of both {\\guillemotleft}+{\\guillemotright} and {\\guillemotleft}-{\\guillemotright} polarities for each prominence. An interpretation in the frame of the existence of oppositely directed magnetic fields is noted.

  9. North Polar Cap

    Science.gov (United States)

    2004-01-01

    [figure removed for brevity, see original site] This week we will be looking at five examples of laminar wind flow on the north polar cap. On Earth, gravity-driven south polar cap winds are termed 'catabatic' winds. Catabatic winds begin over the smooth expanse of the cap interior due to temperature differences between the atmosphere and the surface. Once begun, the winds sweep outward along the surface of the polar cap toward the sea. As the polar surface slopes down toward sealevel, the wind speeds increase. Catabatic wind speeds in the Antartic can reach several hundreds of miles per hour. In the images of the Martian north polar cap we can see these same type of winds. Notice the streamers of dust moving downslope over the darker trough sides, these streamers show the laminar flow regime coming off the cap. Within the trough we see turbulent clouds of dust, kicked up at the trough base as the winds slow down and enter a chaotic flow regime. The horizontal lines in these images are due to framelet overlap and lighting conditions over the bright polar cap. Image information: VIS instrument. Latitude 86.5, Longitude 64.5 East (295.5 West). 40 meter/pixel resolution. Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time. NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen

  10. Half-lives for proton emission, alpha decay, cluster radioactivity, and cold fission processes calculated in a unified theoretical framework

    CERN Document Server

    Duarte, S B; Guzmán, F; Di Marco, A; García, F; Rodríguez, O; Gonçalves, M

    2002-01-01

    Half-life values of spontaneous nuclear decay processes are presented in the framework of the effective liquid drop model (ELDM) using the combination of varying mass asymmetry shape description for the mass transfer (VMAS) and Werner-Wheeler's inertia coefficient (WW). The calculated half lives of ground-state to ground-state transitions for proton emission, alpha decay, cluster radioactivity, and cold fission processes are compared with experimental data. These comparisons show that the ELDM is a very efficient model to describe these different decay processes in a same, unified, theoretical framework. A table listing the predicted half-life values, tau sub c , is presented for all possible cases of spontaneous nuclear breakup such that -7.30 -17.0, where tau is the total half life of the parent nucleus.

  11. An example of the association of X-ray and UV emission with H-alpha surges

    Science.gov (United States)

    Schmieder, B.; Mein, P.; Simnett, G. M.; Tandberg-Hanssen, E.

    1988-01-01

    From H-alpha UV, and X-ray data, the nature of a well-observed surge on November 12, 1980 has been studied to try to understand the relationships between the mechanical motions and the high-temperature emissions. The cool (H-alpha) and the hot (O v) parts of the surge plasma both show velocities in the range of 100-120 km/s. The kinetic and potential energies of the surge are two orders of magnitude higher than the radiative energy. The observations suggest that the surge occurs in open structures parallel to one leg of a large scale coronal magnetic loop. The energy is released principally in the open structure (surge) and only a small amount heats the coronal loop (X-ray signature). This energy division should probably not be treated as a general characteristic of surge events. Different events are expected to exhibit a different energy balance, and this can account for the lack of a consensus in the previous literature regarding surge/X-ray associations.

  12. Development of a real-time monitor for airborne alpha emissions. First quarter report, TTP AL 142003

    Energy Technology Data Exchange (ETDEWEB)

    Gritzo, R.E.; Fowler, M.M.

    1994-02-01

    This is the first quarterly report for Fiscal Year (FY) 1994 for TTP AL 142003, Development of a Real-Time Monitor for Airborne Alpha Emissions. Los Alamos National Laboratory (LANL) is developing a new technology for on-line, real-time monitoring of incinerator stacks for low levels of airborne alpha activity. While initially developed for incinerators, this new technology may well find other applications in continuous air monitoring, process monitoring, and monitoring during remediation activities. Referred to as the Large-Volume Flow Thru Detector System (LVFTDS), this technology responds directly to the need for fast responding, high sensitivity effluent monitoring systems. With DOE EM-50 funding, LANL has fabricated a bench-top proof of concept detector system and is conducting tests to evaluate its performance. A second- generation prototype is being designed, based on requirements driven by potential field test sites. An industrial partner is being solicited to license the technology. Field trials of a full-scale detector system are planned for FY 95. Accomplishments during the first quarter of FY 94 are chronicled in this report, including budgetary data. A schedule for the remainder of the fiscal year is also provided.

  13. The VIMOS Ultra Deep Survey: Lyman Alpha Emission and Stellar Populations of Star-Forming Galaxies at 2

    CERN Document Server

    Hathi, Nimish P

    2016-01-01

    The extensive ground-based spectroscopy campaign from the VIMOS Ultra-Deep Survey (VUDS), and the deep multi-wavelength photometry in three very well observed extragalactic fields (ECDFS, COSMOS, VVDS), allow us to investigate physical properties of a large sample (~4000 galaxies) of spectroscopically confirmed faint (i_{AB}20A) increases from ~10% at z~2 to ~40% at z~5-6, which is consistent with previous studies that employ higher Lyman alpha EW cut. This increase in the LAE fraction could be, in part, due to a decrease in the dust content of galaxies as redshift increases. When we compare best-fit SED estimated stellar parameters for LAEs and non-LAEs, we find that E(B-V) is smaller for LAEs at all redshifts and the difference in the median E(B-V) between LAEs and non-LAEs increases as redshift increases, from 0.05 at z~2 to 0.1 at z~3.5 to 0.2 at z~5-6. For the luminosities probed here (~L*), we find that star formation rates (SFRs) and stellar masses of galaxies, with and without Lyman alpha in emission,...

  14. Alpha and light nucleus emission within a generalized liquid drop model

    Science.gov (United States)

    Royer, G.; Bonilla, C.; Moustabchir, R.

    2002-11-01

    The potential energy governing the spontaneous α, C, O, F, Ne, Mg and Si emissions has been determined within a generalized liquid drop model including the proximity effects between the emitted light nucleus and the daughter one and taking into account empirically the experimental Q value. The decay path has been described by a quasi-molecular shape sequence leading rapidly to two spherical touching nuclei before crossing the barrier. The partial half-lives deduced from the WKB barrier penetration probabability are in very good agreement with experimental data and accurate analytical expressions are proposed. The partial half-lives of the Be, Li, He and H sub-barrier emissions have been calculated by adding an excitation energy to the Q value and new formulae are given.

  15. Reactor neutron activation analysis for aluminium in the presence of phosphorus and silicon. Contributions of /sup 28/Al activities from /sup 31/P (n,. cap alpha. ) /sup 28/Al and /sup 28/Si (n,p) /sup 28/Al reactions

    Energy Technology Data Exchange (ETDEWEB)

    Mizumoto, Yoshihiko (Kinki Univ., Higashi-Osaka, Osaka (Japan). Faculty of Science and Technology); Iwata, Shiro; Sasajima, Kazuhisa; Yoshimasu, Fumio; Yase, Yoshiro

    1984-01-01

    Reactor neutron activation analysis for aluminium in samples containing phosphorus and silicon was studied. The experiments were performed by using pneumatic tube of the Kyoto University Reactor (KUR). At first, the ratios of the /sup 28/Al activity produced from /sup 27/Al(n, ..gamma..) /sup 28/Al reaction by thermal neutrons to that from /sup 31/P(n, ..cap alpha..)/sup 28/Al reaction by fast neutrons, and to that from /sup 28/Si(n, p)/sup 28/Al reaction were measured by ..gamma..-ray spectrometry. With a ratio of about 5 for the thermal to fast neutron flux of KUR, the ratio of the /sup 28/Al activity from aluminium to that from phosphorus was to be 812 +- 7, and to that from silicon 282 +- 3. Secondly, the contributions of /sup 28/Al activities from phosphorus and silicon and the determination limit of aluminium were calculated for various parameters, such as fast neutron flux, thermal to fast neutron flux ratio, amounts of phosphorus and silicon, etc. Thirdly, on the basis of these results, aluminium contents in spinal cords and brains of amyotrophic lateral sclerosis, Parkinsonism-dementia complex and control cases were determined.

  16. Detection of Lyman-Alpha Emission From a Triple Imaged z=6.85 Galaxy Behind MACS J2129.4-0741

    CERN Document Server

    Huang, Kuang-Han; Schmidt, Kasper B; Hoag, Austin; Bradač, Maruša; Treu, Tommaso; Dijkstra, Mark; Fontana, Adriano; Henry, Alaina; Malkan, Matthew; Mason, Charlotte; Morishita, Takahiro; Pentericci, Laura; Ryan, Russell E; Trenti, Michele; Wang, Xin

    2016-01-01

    We report the detection of Ly$\\alpha$ emission at $\\sim9538$\\AA{} in the Keck/DEIMOS and \\HST WFC3 G102 grism data from a triply-imaged galaxy at $z=6.846\\pm0.001$ behind galaxy cluster MACS J2129.4$-$0741. Combining the emission line wavelength with broadband photometry, line ratio upper limits, and lens modeling, we rule out the scenario that this emission line is \\oii at $z=1.57$. After accounting for magnification, we calculate the weighted average of the intrinsic Ly$\\alpha$ luminosity to be $\\sim1.3\\times10^{42}~\\mathrm{erg}~\\mathrm{s}^{-1}$ and Ly$\\alpha$ equivalent width to be $74\\pm15$\\AA{}. Its intrinsic UV absolute magnitude at 1600\\AA{} is $-18.6\\pm0.2$ mag and stellar mass $(1.5\\pm0.3)\\times10^{7}~M_{\\odot}$, making it one of the faintest (intrinsic $L_{UV}\\sim0.14~L_{UV}^*$) galaxies with Ly$\\alpha$ detection at $z\\sim7$ to date. Its stellar mass is in the typical range for the galaxies thought to dominate the reionization photon budget at $z\\gtrsim7$; the inferred Ly$\\alpha$ escape fraction is ...

  17. Emission-line stars discovered in the UKST H-alpha survey of the Large Magellanic Cloud; Part 1: Hot stars

    CERN Document Server

    Reid, Warren A

    2012-01-01

    We present new, accurate positions, spectral classifications, radial and rotational velocities, H-alpha fluxes, equivalent widths and B,V,I,R magnitudes for 579 hot emission-line stars (classes B0 - F9) in the Large Magellanic Cloud which include 469 new discoveries. Candidate emission line stars were discovered using a deep, high resolution H-alpha map of the central 25 deg2 of the LMC obtained by median stacking a dozen 2 hour H-alpha exposures taken with the UK Schmidt Telescope. Spectroscopic follow-up observations on the AAT, UKST, VLT, the SAAO 1.9m and the MSSSO 2.3m telescope have established the identity of these faint sources down to magnitude R~23 for H-alpha (4.5 x 10^-17 ergs cm^2 s^-1 Ang). Confirmed emission-line stars have been assigned an underlying spectral classification through cross-correlation against 131 absorption line template spectra covering the range O1 to F8. We confirm 111 previously identified emission line stars and 64 previously known variable stars with spectral types hotter ...

  18. The Tremaine-Weinberg method for pattern speeds using H-alpha emission from ionized gas

    CERN Document Server

    Beckman, John E; Piñol, Núria; Toonen, Silvia; Hernandez, Olivier; Carignan, Claude

    2007-01-01

    The Fabry-Perot interferometer FaNTOmM was used at the 3.6m Canada France Hawaii Telescope and the 1.6m Mont Megantic Telescope to obtain data cubes in H-alpha of 9 nearby spiral galaxies from which maps in integrated intensity, velocity, and velocity dispersion were derived. We then applied the Tremaine-Weinberg method, in which the pattern speed can be deduced from its velocity field, by finding the integrated value of the mean velocity along a slit parallel to the major axis weighted by the intensity and divided by the weighted mean distance of the velocity points from the tangent point measured along the slit. The measured variables can be used either to make separate calculations of the pattern speed and derive a mean, or in a plot of one against the other for all the points on all slits, from which a best fit value can be derived. Linear fits were found for all the galaxies in the sample. For two galaxies a clearly separate inner pattern speed with a higher value, was also identified and measured.

  19. The outer atmosphere of the M-type supergiant alpha Orionis KI 7699A emission

    CERN Document Server

    Plez, B; Plez, Bertrand; Lambert, David L.

    2002-01-01

    Spatially-resolved high-resolution long-slit spectra of Betelgeuse's circumstellar shell are described for a spectral window centered on the 7699\\AA resonance line of neutral potassium. The K I emission from resonance fluorescent scattering of photospheric photons which is mapped out to 50 arcsec from the star is approximately spherically symmetric with a brightness decreasing as r^{-2.36 \\pm 0.03}, where $r$ is the radial distance from the star. Our measurements together with the earlier theoretical interpretation by Rodgers & Glassgold suggest that the mass loss rate is about 2 . 10^{-6} solar mass/year. The K I emission is far from homogeneous: intensity inhomogeneities are seen down to the seeing limit of about 1 arcsec and the velocity resolution of about 2 km/s. There is clear evidence for a thin shell of 50 arcsec radius. This is identified with the weaker circumstellar absorption component known as S2. Estimates are made of the density of K atoms in this shell (approx. 6 . 10^{-5} cm^{-3}).

  20. 中国节能减排:征税还是部门总量控制与交易%Energy Saving and Emission Reduction in China: Emission Tax or Sectoral Cap and Emission Trading

    Institute of Scientific and Technical Information of China (English)

    曹荣湘

    2011-01-01

    At present, energy saving and emission reduction in China is confronting arduous task. Recently, discussions about carbon emission tax are paid much attention. From the theoretical point of view, carbon emission tax is the best way to cope with climate change and promote energy saving and emission reduction, but it needs be cautious to adopt carbon emission tax policy in the context of China's current specific system and macroeconomic situation. Before the adoption of carbon emission tax, we must assess the emission reduction effect of carbon emission tax, the impact of carbon emission tax on economic growth, the shift of carbon emission tax and other related issues. We need further study carbon emission tax and revise the timetable of carbon emission tax. Meanwhile, we should focus on carbon emission trading and make great efforts to study, explore and establish China's carbon emission trading system.%目前,中国的节能减排面临艰巨的任务。近来,有关碳税的讨论广受关注。从理论上来看,碳税是应对气候变化、推进节能减排的最优路径。但在中国目前的特殊体制和宏观经济形势下,征收碳税须慎之又慎。我们必须首先解决好碳税的减排效果、碳税对经济增长的冲击、税负转嫁、税收中性等问题后再考虑开征碳税。对碳税要展开进一步研究,要对2012年开征的时间表进行重新修正。同时,要把重点对准碳交易,花大力气去研究、探索、建立中国的碳交易体系。

  1. Synthesis of tritiated 1-alpha-methadol and 1-alpha-acetylmethadol

    Energy Technology Data Exchange (ETDEWEB)

    Thang, D.C.; Nam, N.H.; Pontikis, R. (Institut National de la Sante et de la Recherche Medicale (INSERM), Hopital Fernand Widal, 75 - Paris (France)); Pichat, L. (CEA Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France). Service des Molecules Marquees)

    1982-04-01

    dl-Methadone was resolved by crystallization of its ammonium d- ..cap alpha.. -bromocamphor-..pi..-sulfonate salt to give d-methadone. The latter in ethyl acetate solution was reduced with tritium gas to 1-..cap alpha..-methadol /sup 3/H in presence of Adams platinum oxide at normal temperature and pressure. Acetylation of 1-..cap alpha..-carbinol hydrochloride by means of acetyl chloride afforded 1-..cap alpha..-acetylmethadol /sup 3/H, specific activity: 20 Ci/mMole. The positions and extent of tritium labelling were determined by /sup 3/H NMR spectroscopy.

  2. Evolution and Activity in the Solar Corona: A Comparison of Coronal and Chromospheric Structures Seen in Soft X-Rays, White Light and H-Alpha Emission

    Science.gov (United States)

    Bagenal, Fran

    2001-01-01

    The work completed under this project, 'Evolution and Activity in the Solar Corona: A Comparison of Coronal and Chromospheric Structures Seen in Soft X-Rays, White Light and H-Alpha Emission', includes the following presentations: (1) Analysis of H-alpha Observations of High-altitude Coronal Condensations; (2) Multi-spectral Imaging of Coronal Activity; (3) Measurement and Modeling of Soft X-ray Loop Arcades; (4) A Study of the Origin and Dynamics of CMEs; and various poster presentations and thesis dissertations.

  3. First results from Faint Infrared Grism Survey (FIGS): first simultaneous detection of Lyman-{\\alpha} emission and Lyman break from a galaxy at z=7.51

    CERN Document Server

    Tilvi, V; Malhotra, S; Finkelstein, S L; Rhoads, J E; Windhorst, R; Grogin, N A; Koekemoer, A; Zakamska, N; Ryan, R; Christensen, L; Hathi, N; Pharo, J; Joshi, B; Yang, H; Gronwall, C; Cimatti, A; Walsh, J; OConnell, R; Straughn, A; Ostlin, G; Rothberg, B; Livermore, R C; Hibon, P; Gardner, Jonathan P

    2016-01-01

    Galaxies at high redshifts provide a valuable tool to study cosmic dawn, and therefore it is crucial to reliably identify these galaxies. Here, we present an unambiguous and first simultaneous detection of both the Lyman-\\alpha emission and the Lyman break from a z = 7.512+/- 0.004 galaxy, observed in the Faint Infrared Grism Survey (FIGS). These spectra, taken with G102 grism on Hubble Space Telescope (HST), show a significant emission line detection (6{\\sigma}) in multiple observational position angles (PA), with total integrated Ly{\\alpha} line flux of 1.06+/- 0.12 e10-17erg s-1cm-2. The line flux is nearly a factor of four higher than the previous MOSFIRE spectroscopic observations of faint Ly{\\alpha} emission at {\\lambda} = 1.0347{\\mu}m, yielding z = 7.5078+/- 0.0004. This is consistent with other recent observations implying that ground-based near-infrared spectroscopy underestimates total emission line fluxes, and if confirmed, can have strong implications for reionization studies that are based on gro...

  4. Half-lives for proton emission, alpha decay, cluster radioactivity, and cold fission processes calculated in a unified theoretical framework

    Energy Technology Data Exchange (ETDEWEB)

    Duarte, S.B.; Tavares, O.A.P.; Guzman, F.; Dimarco, A. [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Garcia, F. [Sao Paulo Univ., SP (Brazil). Inst. de Fisica; Universidade Estadual de Santa Cruz, Ilheus, BA (Brazil). Dept. de Ciencias Exatas e Tecnologicas; Rodriguez, O. [Sao Paulo Univ., SP (Brazil). Inst. de Fisica; Instituto Superior de Ciencias e Tecnologia Nucleares, La Habana (Cuba); Goncalves, M. [Instituto de Radioprotecao e Dosimetria (IRD), Rio de Janeiro, RJ (Brazil)

    2002-01-01

    Half-life values of spontaneous nuclear decay processes are presented in the framework of the Effective Liquid Drop Model (ELDM) using the combination of varying mass asymmetry shape description for the mass transfer with Werner-Wheeler's inertia coefficient V{sub MAS}/WW. The calculated half-lives of ground-state to ground-state transitions for the proton emission, alpha decay, cluster radioactivity, and cold fission processes are compared with experimental data. Results have shown that the ELDM is a very efficient model to describe these different decay processes in a same, unified theoretical framework. A Table listing the predicted half-life values, {tau}{sub c} is presented for all possible cases of spontaneous nuclear break-up such that -7.30 <{approx_equal} log{sub 10} {tau}{sub c} [S] <{approx_equal} 27.50 and log {sub 10}({tau}/{tau}{sub c}) > -17.0, where {tau} is the total half-life of the parent nucleus. (author)

  5. Calculated half-lives and kinetic energies for spontaneous emission of heavy ions from nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Poenaru, D.N.; Greiner, W.; Depta, K.; Ivascu, M.; Mazilu, D.; Sandulescu, A.

    1986-05-01

    The most probable decays by spontaneous emission of heavy ions are listed for nuclides with Z = 47--106 and total half-lives>1 ..mu..sec. Partial half-lives, branching ratios relative to ..cap alpha.. decay, kinetic energies, and Q values are estimated by using the analytical superasymmetric fission model, a semiempirical formula for those ..cap alpha..-decay lifetimes which have not been measured, and the new Wapstra--Audi mass tables. Numerous ''stable'' nuclides with Z>40 are found to be metastable with respect to the new decay modes. The current experimental status is briefly reviewed.

  6. HST/COS Spectra of DF Tau and V4046 SGR: First Detection of Molecular Hydrogen Absorption Against the Ly$\\alpha$ Emission Line

    CERN Document Server

    Yang, Hao; France, Kevin

    2011-01-01

    We report the first detection of molecular hydrogen (H$_{2}$) absorption in the Lyman-$\\alpha$ emission line profiles of two classical T Tauri stars (CTTSs), DF Tau and V4046 Sgr, observed by \\emph{HST}/COS. This absorption is the energy source for many of the Lyman-band H$_{2}$ fluorescent lines commonly seen in the far-ultraviolet spectra of CTTSs. We find that the absorbed energy in the H$_{2}$ pumping transitions from a portion of the Lyman-$\\alpha$ line significantly differ from the amount of energy in the resulting fluorescent emission. By assuming additional absorption in the H I Lyman-$\\alpha$ profile along our light of sight, we can correct the H$_{2}$ absorption/emission ratios so that they are close to unity. The required H I absorption for DF Tau is at a velocity close to the radial velocity of the star, consistent with H I absorption in the edge-on disk and interstellar medium. For V4046 Sgr, a nearly face-on system, the required absorption is between +100 km/s and +290 km/s, most likely resultin...

  7. Keck/MOSFIRE Spectroscopy of z=7-8 Galaxies: Lyman-alpha Emission from a Galaxy at z=7.66

    CERN Document Server

    Song, Mimi; Livermore, Rachael C; Capak, Peter L; Dickinson, Mark; Fontana, Adriano

    2016-01-01

    We report the results from some of the deepest Keck/MOSFIRE data yet obtained for candidate $z \\gtrsim 7$ galaxies. Our data show one significant line detection with 6.5$\\sigma$ significance in our combined 10 hours of integration which is independently detected on more than one night, ruling out the possibility that the detection is spurious. The asymmetric line profile and non-detection in the optical bands strongly imply that the detected line is Ly$\\alpha$ emission from a galaxy at $z$(Ly$\\alpha)=7.6637 \\pm 0.0011$, making it the fourth spectroscopically confirmed galaxy at $z>7.5$. This galaxy is bright in the rest-frame ultraviolet (UV; $M_{\\rm UV} \\sim -21.2$) with a moderately blue UV slope ($\\beta=-2.2^{+0.3}_{-0.2}$), and exhibits a rest-frame Ly$\\alpha$ equivalent width of EW(Ly$\\alpha$) $\\sim 15.6^{+5.6}_{-3.6}$ \\AA. The non-detection of the 11 other $z \\sim$ 7--8 galaxies in our long 10 hr integration, reaching a median 5$\\sigma$ sensitivity of 28 \\AA\\ in the rest-frame EW(Ly$\\alpha$), implies a ...

  8. The Rest-Frame Optical Spectroscopic Properties of Ly$\\alpha$-Emitters at $z\\sim2.5$: The Physical Origins of Strong Ly$\\alpha$ Emission

    CERN Document Server

    Trainor, Ryan F; Steidel, Charles C; Rudie, Gwen C

    2016-01-01

    We present rest-frame optical spectra of 60 faint ($R_{AB}\\sim 27$; $L\\sim0.1 L_*$) Ly$\\alpha$-selected galaxies (LAEs) at $z\\approx2.56$. The average LAE is consistent with the extreme low-metallicity end of the continuum-selected galaxy distribution at $z\\approx2-3$. In particular, the LAEs have extremely high [OIII] $\\lambda$5008/H$\\beta$ ratios (log([OIII]/H$\\beta$) $\\sim$ 0.8) and low [NII] $\\lambda$6585/H$\\alpha$ ratios (log([NII]/H$\\alpha$) $<-1.15$). Using the [OIII] $\\lambda$4364 auroral line, we find that the star-forming regions in faint LAEs are characterized by high electron temperatures ($T_e\\approx1.8\\times10^4$K), low oxygen abundances (12 + log(O/H) $\\approx$ 8.04, $Z_{neb}\\approx0.22Z_\\odot$), and high excitations with respect to more luminous galaxies. Our faintest LAEs have line ratios consistent with even lower metallicities, including six with 12 + log(O/H) $\\approx$ 6.9$-$7.4 ($Z_{neb}\\approx0.02-0.05Z_\\odot$). We interpret these observations in light of new models of stellar evoluti...

  9. RESOLVING THE OPTICAL EMISSION LINES OF Ly{alpha} BLOB ''B1'' AT z = 2.38: ANOTHER HIDDEN QUASAR

    Energy Technology Data Exchange (ETDEWEB)

    Overzier, R. A. [Department of Astronomy, University of Texas at Austin, 1 University Station C1400, Austin, TX 78712 (United States); Nesvadba, N. P. H. [Institut d' Astrophysique Spatiale, CNRS, Universite Paris-Sud, F-91405 Orsay (France); Dijkstra, M. [Max-Planck-Institut fuer Astrophysik, Karl-Schwarzschild-Str. 1, D-85741 Garching (Germany); Hatch, N. A. [School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD (United Kingdom); Lehnert, M. D. [GEPI, Observatoire de Paris, UMR 8111, CNRS, Universite Paris Diderot, 5 place Jules Janssen, F-92190 Meudon (France); Villar-Martin, M. [Centro de Astrobioloia (INTA-CSIC), Carretera de Ajalvir, km 4, E-28850 Torrejon de Ardoz, Madrid (Spain); Wilman, R. J. [Department of Physics, University of Durham, South Road, Durham DH13LE (United Kingdom); Zirm, A. W., E-mail: overzier@astro.as.utexas.edu [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen (Denmark)

    2013-07-10

    We have used the SINFONI near-infrared integral field unit on the Very Large Telescope to resolve the optical emission line structure of one of the brightest (L{sub Ly{alpha}} Almost-Equal-To 10{sup 44} erg s{sup -1}) and nearest (z Almost-Equal-To 2.38) of all Ly{alpha} blobs (LABs). The target, known in the literature as object {sup B}1{sup ,} lies at a redshift where the main optical emission lines are accessible in the observed near-infrared. We detect luminous [O III] {lambda}{lambda}4959, 5007 and H{alpha} emission with a spatial extent of at least 32 Multiplication-Sign 40 kpc (4'' Multiplication-Sign 5''). The dominant optical emission line component shows relatively broad lines (600-800 km s{sup -1}, FWHM) and line ratios consistent with active galactic nucleus (AGN) photoionization. The new evidence for AGN photoionization, combined with previously detected C IV and luminous, warm infrared emission, suggest that B1 is the site of a hidden quasar. This is confirmed by the fact that [O II] is relatively weak compared with [O III] (extinction-corrected [O III]/[O II] of about 3.8), which is indicative of a high, Seyfert-like ionization parameter. From the extinction-corrected [O III] luminosity we infer a bolometric AGN luminosity of {approx}3 Multiplication-Sign 10{sup 46} erg s{sup -1}, and further conclude that the obscured AGN may be Compton-thick given existing X-ray limits. The large line widths observed are consistent with clouds moving within the narrow-line region of a luminous QSO. The AGN scenario is capable of producing sufficient ionizing photons to power the Ly{alpha}, even in the presence of dust. By performing a census of similar objects in the literature, we find that virtually all luminous LABs harbor obscured quasars. Based on simple duty-cycle arguments, we conclude that AGNs are the main drivers of the Ly{alpha} in LABs rather than the gravitational heating and subsequent cooling suggested by cold stream models. We

  10. Lyman alpha emission from the first galaxies : signatures of accretion and infall in the presence of line trapping

    NARCIS (Netherlands)

    Latif, M. A.; Schleicher, Dominik R. G.; Spaans, M.; Zaroubi, S.

    2011-01-01

    The formation of the first galaxies is accompanied by large accretion flows and virialization shocks, during which the gas is shock heated to temperatures of similar to 10(4) K, leading to potentially strong fluxes in the Lyman alpha line. Indeed, a number of Lyman alpha blobs have been detected at

  11. A coronagraphic absorbing cloud reveals the narrow-line region and extended Lyman-$\\alpha$ emission of QSO J0823+0529

    CERN Document Server

    Fathivavsari, Hassan; Noterdaeme, Pasquier; Pâris, Isabelle; Finley, Hayley; López, Sebastian; Srianand, Raghunathan; Sánchez, Paula

    2015-01-01

    We report long-slit spectroscopic observations of the quasar SDSS J082303.22+052907.6 ($z_{\\rm CIV}$$\\sim$3.1875), whose Broad Line Region (BLR) is partly eclipsed by a strong damped Lyman-$\\alpha$ (DLA; log$N$(HI)=21.7) cloud. This allows us to study the Narrow Line Region (NLR) of the quasar and the Lyman-$\\alpha$ emission from the host galaxy. Using CLOUDY models that explain the presence of strong NV and PV absorption together with the detection of SiII$^*$ and OI$^{**}$ absorption in the DLA, we show that the density and the distance of the cloud to the quasar are in the ranges 180 $$ $r_0$ $>$230 pc, respectively. Sizes of the neutral($\\sim$2-9pc) and highly ionized phases ($\\sim$3-80pc) are consistent with the partial coverage of the CIV broad line region by the CIV absorption from the DLA (covering factor of $\\sim$0.85). We show that the residuals are consistent with emission from the NLR with CIV/Lyman-$\\alpha$ ratios varying from 0 to 0.29 through the profile. Remarkably, we detect extended Lyman-$\\...

  12. A Relativistic Fe K-alpha Emission Line in the Intermediate Luminosity BeppoSAX Spectrum of the Galactic Microquasar V4641 Sgr

    CERN Document Server

    Miller, J M; in 't Zand, J J M; Reynolds, C S; Wijnands, R; Nowak, M A; Lewin, W H G

    2002-01-01

    Broad Fe K-alpha emission lines have recently been reported in a number of Galactic black holes. Such lines are useful accretion flow diagnostics because they may be produced at the inner accretion disk and shaped by relativistic effects, but in general they have only been observed at luminosities of L_X = 10^(37-38) erg/s in soft X-rays. The Galactic microquasar V4641 Sgr -- widely known for its 12.2 Crab (1.5-12 keV) outburst in 1999 September -- displayed low-level activity in 1999 March. BeppoSAX observed the source in this state and Fe K-alpha line emission was found (in 't Zand et al. 2000). In re-analyzing these data, we find strong evidence that the Fe K-alpha line profile is broadened. For the most likely values of the source distance and black hole mass measured by Orosz et al. (2001), our fits to the total spectrum indicate that the source was observed at a luminosity of L_X = 1.9 (+1.0, -0.8) * 10^(36) erg/s (2-10 keV), or L_(2-10)/L_(Eddington) = 1.8 (+0.9, -0.8) * 10^(-3). Advection-dominated ac...

  13. Polar Cap Patch Dynamics

    Science.gov (United States)

    2013-04-25

    cap arcs Citation: Hosokawa, K., J. I. Moen, K. Shiokawa, and Y. Otsuka ( 2011 ), Motion of polar cap arcs , J. Geophys. Res. , 116 , A01305, doi...K., J. I. Moen, K. Shiokawa, and Y. Otsuka , (2011), Decay of polar cap patch, J. Geophys. Res., 116, A05308, doi:10.1029/2010JA016287, Abstract. We

  14. An HST/COS Observation of Broad Ly$\\alpha$ Emission and Associated Absorption Lines of the BL Lacertae Object H 2356-309

    CERN Document Server

    Fang, Taotao; Buote, David A; Stocke, John T; Shull, J Michael; Canizares, Claude R; Gastaldello, Fabio

    2014-01-01

    Weak spectral features in BL Lacertae objects (BL Lac) often provide a unique opportunity to probe the inner region of this rare type of active galactic nucleus. We present a Hubble Space Telescope/Cosmic Origins Spectrograph observation of the BL Lac H 2356-309. A weak Ly$\\alpha$ emission line was detected. This is the fourth detection of a weak Ly$\\alpha$ emission feature in the ultraviolet (UV) band in the so-called "high energy peaked BL Lacs", after Stocke et al. Assuming the line-emitting gas is located in the broad line region (BLR) and the ionizing source is the off-axis jet emission, we constrain the Lorentz factor ($\\Gamma$) of the relativistic jet to be $\\geq 8.1$ with a maximum viewing angle of 3.6$^\\circ$. The derived $\\Gamma$ is somewhat larger than previous measurements of $\\Gamma \\approx 3 - 5$, implying a covering factor of $\\sim$ 3% of the line-emitting gas. Alternatively, the BLR clouds could be optically thin, in which case we constrain the BLR warm gas to be $\\sim 10^{-5}\\rm\\ M_{\\odot}$. ...

  15. In vivo visualization of alpha-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy]benzoxazole positron emission tomography in multiple system atrophy.

    Science.gov (United States)

    Kikuchi, Akio; Takeda, Atsushi; Okamura, Nobuyuki; Tashiro, Manabu; Hasegawa, Takafumi; Furumoto, Shozo; Kobayashi, Michiko; Sugeno, Naoto; Baba, Toru; Miki, Yasuo; Mori, Fumiaki; Wakabayashi, Koichi; Funaki, Yoshihito; Iwata, Ren; Takahashi, Shoki; Fukuda, Hiroshi; Arai, Hiroyuki; Kudo, Yukitsuka; Yanai, Kazuhiko; Itoyama, Yasuto

    2010-06-01

    The histopathological hallmark of multiple system atrophy is the appearance of intracellular inclusion bodies, named glial cytoplasmic inclusions, which are mainly composed of alpha-synuclein fibrils. In vivo visualization of alpha-synuclein deposition should be used for the diagnosis and assessment of therapy and severity of pathological progression in multiple system atrophy. Because 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy] benzoxazole could stain alpha-synuclein-containing glial cytoplasmic inclusions in post-mortem brains, we compared the carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy] benzoxazole positron emission tomography findings of eight multiple system atrophy cases to those of age-matched normal controls. The positron emission tomography data demonstrated high distribution volumes in the subcortical white matter (uncorrected P benzoxazole positron emission tomography is a promising surrogate marker for monitoring intracellular alpha-synuclein deposition in living brains.

  16. Incorporating Wind Generation in Cap and Trade Programs

    Energy Technology Data Exchange (ETDEWEB)

    Bluestein, J.; Salerno, E.; Bird, L.; Vimmerstedt, L.

    2006-07-01

    Cap and trade programs are increasingly being used to reduce emissions from electricity generation in the United States. Cap and trade programs primarily target emitting generators, but programs have also included renewable generators, such as wind generators. States cite several reasons why they have considered the policy option of including renewable generators in cap and trade programs: to provide an incentive for lower-emitting generation, to achieve emissions reductions in non-capped pollutants, and to gain local economic benefits associated with renewable energy projects. The U.S. Environmental Protection Agency also notes these rationales for considering this policy alternative, and the National Association of Regulatory Commissioners (NARUC) passed a resolution supporting the inclusion of renewable energy in cap and trade programs. This report explores why states consider this policy option, what participation could mean for wind generators, and how wind generation can most effectively be included in state, federal, and regional cap and trade programs.

  17. Physical Properties of Spectroscopically-Confirmed Galaxies at $z\\ge6$. III. Stellar Populations from SED Modeling with Secure Ly$\\alpha$ Emission and Redshifts

    CERN Document Server

    Jiang, Linhua; Cohen, Seth H; Egami, Eiichi; Windhorst, Rogier A; Fan, Xiaohui; Dave, Romeel; Kashikawa, Nobunari; Mechtley, Matthew; Ouchi, Masami; Shimasaku, Kazuhiro; Clement, Benjamin

    2015-01-01

    We present a study of stellar populations in a sample of spectroscopically-confirmed Lyman-break galaxies (LBGs) and Ly$\\alpha$ emitters (LAEs) at $5.7emission estimated from the observed Ly$\\alpha$ flux, we are able to break the strong degeneracy of model spectra between young galaxies with prominent nebular emission and older galaxies with strong Balmer breaks. The results show that our galaxies cover a wide range of ages from several to a few hundred million years (Myr), and a wide range of stellar masses from $\\sim10^8$ to $\\sim10^{11}$ $M_{\\odot}$. These galaxies can be roughly divided into an `old' subsample and a `young' subsample. The `old' subsample consists of galaxies older than 100 Myr,...

  18. An Observational Pursuit for Population III Stars in a Ly_alpha Emitter at z=6.33 through HeII Emission

    CERN Document Server

    Nagao, T; Maiolino, R; Marconi, A; Taniguchi, Y; Aoki, K; Ajiki, M; Shioya, Y; Nagao, Tohru; Motohara, Kentaro; Maiolino, Roberto; Marconi, Alessandro; Taniguchi, Yoshiaki; Aoki, Kentaro; Ajiki, Masaru; Shioya, Yasuhiro

    2005-01-01

    We present a very deep near-infrared spectroscopic observation of a strong Ly_alpha emitter at z=6.33, SDF J132440.6+273607, which we used to search for HeII 1640. This emission line is expected if the target hosts a significant number of population III stars. Even after 42 ksec of integration with the Subaru/OHS spectrograph, no emission-line features are detected in the JH band, which confirms that SDF J132440.6+273607 is neither an active galactic nucleus nor a low-$z$ emission-line object. We obtained a 2sigma upper-limit of 9.06e-18 ergs/s/cm^2 on the HeII 1640 emission line flux, which corresponds to a luminosity of 4.11e42 ergs/s. This upper-limit on the HeII 1640 luminosity implies that the upper limit on population III star-formation rate is in the range 4.9--41.2 M_sun/yr if population III stars suffer no mass loss, and in the range 1.8--13.2 M_sun/yr if strong mass loss is present. The non-detection of HeII in SDF J132440.6+273607 at z=6.33 may thus disfavor weak feedback models for population III ...

  19. Review of Quantitative Monitoring Methodologies for Emissions Verification and Accounting for Carbon Dioxide Capture and Storage for California’s Greenhouse Gas Cap-and-Trade and Low-Carbon Fuel Standard Programs

    Energy Technology Data Exchange (ETDEWEB)

    Oldenburg, Curtis M. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Earth Sciences Division; Birkholzer, Jens T. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Earth Sciences Division

    2014-12-23

    The Cap-and-Trade and Low Carbon Fuel Standard (LCFS) programs being administered by the California Air Resources Board (CARB) include Carbon Dioxide Capture and Storage (CCS) as a potential means to reduce greenhouse gas (GHG) emissions. However, there is currently no universal standard approach that quantifies GHG emissions reductions for CCS and that is suitable for the quantitative needs of the Cap-and-Trade and LCFS programs. CCS involves emissions related to the capture (e.g., arising from increased energy needed to separate carbon dioxide (CO2) from a flue gas and compress it for transport), transport (e.g., by pipeline), and storage of CO2 (e.g., due to leakage to the atmosphere from geologic CO2 storage sites). In this project, we reviewed and compared monitoring, verification, and accounting (MVA) protocols for CCS from around the world by focusing on protocols specific to the geologic storage part of CCS. In addition to presenting the review of these protocols, we highlight in this report those storage-related MVA protocols that we believe are particularly appropriate for CCS in California. We find that none of the existing protocols is completely appropriate for California, but various elements of all of them could be adopted and/or augmented to develop a rigorous, defensible, and practical surface leakage MVA protocol for California. The key features of a suitable surface leakage MVA plan for California are that it: (1) informs and validates the leakage risk assessment, (2) specifies use of the most effective monitoring strategies while still being flexible enough to accommodate special or site-specific conditions, (3) quantifies stored CO2, and (4) offers defensible estimates of uncertainty in monitored properties. California’s surface leakage MVA protocol needs to be applicable to the main CO2 storage opportunities (in California and in other states with entities participating in California

  20. Clasp/SJ Observation of Time Variations of Lyman-Alpha Emissions in a Solar Active Region

    Science.gov (United States)

    Ishikawa, S.; Kubo, M.; Katsukawa, Y.; Kano, R.; Narukage, N.; Ishikawa, R.; Bando, T.; Winebarger, A.; Kobayashi, K.; Trujillo Bueno, J.; Auchere, F.

    2016-01-01

    The Chromospheric Lyman-alpha SpectroPolarimeter (CLASP) is a sounding rocket experiment launched on September 3, 2015 to investigate the solar chromosphere, and the slit-jaw (SJ) optical system took Lya images with the high time cadence of 0.6 s. By the CLASP/SJ observation, many time variations in the solar chromosphere with the time scale of time variations and relation to the coronal structure observed by SDO/AIA. We compared the Ly(alpha) time variations at footpoints of coronal magnetic fields observed by AIA 211 Å (approx.2 MK) and AIA 171 Å (0.6 MK), and non-loop regions. As the result, we found the time variations had more in the footpoint regions. On the other hand, the time variations had no dependency on the temperature of the loop.

  1. Investigation of background in large-area neutron detectors due to alpha emission from impurities in aluminium

    CERN Document Server

    Birch, J; Clergeau, J -F; van Esch, P; Ferraton, M; Guerard, B; Hall-Wilton, R; Hultman, L; Höglund, C; Jensen, J; Khaplanov, A; Piscitelli, F

    2015-01-01

    Thermal neutron detector based on films of $^{10}$B$_4$C have been developed as an alternative to $^3$He detectors. In particular, The Multi-Grid detector concept is considered for future large area detectors for ESS and ILL instruments. An excellent signal-to-background ratio is essential to attain expected scientific results. Aluminium is the most natural material for the mechanical structure of of the Multi-Grid detector and other similar concepts due to its mechanical and neutronic properties. Due to natural concentration of $\\alpha$ emitters, however, the background from $\\alpha$ particles misidentified as neutrons can be unacceptably high. We present our experience operating a detector prototype affected by this issue. Monte Carlo simulations have been used to confirm the background as $\\alpha$ particles. The issues have been addressed in the more recent implementations of the Multi-Grid detector by the use of purified aluminium as well as Ni-plating of standard aluminium. The result is the reduction in...

  2. Microtubule's conformational cap

    DEFF Research Database (Denmark)

    Chretien, D.; Janosi, I.; Taveau, J.C.

    1999-01-01

    The molecular mechanisms that allow elongation of the unstable microtubule lattice remain unclear. It is usually thought that the GDP-liganded tubulin lattice is capped by a small layer of GTP- or GDP-P(i)-liganded molecules, the so called "GTP-cap". Here, we point-out that the elastic properties...

  3. A triple-emission fluorescent probe reveals distinctive amyloid fibrillar polymorphism of wild-type alpha-synuclein and its familial Parkinson's disease mutants.

    Science.gov (United States)

    Celej, M Soledad; Caarls, Wouter; Demchenko, Alexander P; Jovin, Thomas M

    2009-08-11

    Intracytoplasmic neuronal deposits containing amyloid fibrils of the 140-amino acid presynaptic protein alpha-synuclein (AS) are the hallmark of Parkinson's (PD) disease and related neurodegenerative disorders. Three point mutations (A53T, A30P, and E46K) are linked to early onset PD. Compared to the wild-type (WT) protein, the mutants aggregate faster in vitro, but their fibrillar products are quite similar. Using the extrinsic multiple-emission probe 4'-(diethylamino)-3-hydroxyflavone (FE), we demonstrate unique and distinct spectroscopic signatures for the amyloid fibrils formed by the WT and mutant AS, presumably indicative of subtle differences in supramolecular structure. The two well-separated emission bands of the FE probe originate from a proton transfer reaction in the excited state. The ratiometric response constitutes a sensitive, tunable reporter of microenvironmental properties such as polarity and hydrogen bonding. The very distinctive fluorescence spectra of the FE probe bound to the four AS variants reflect different tautomeric equilibria in the excited state and the existence of at least two different binding sites in the fibrils for the dye. Deconvolution of the two-dimensional excitation-emission spectra leads to estimations of different local dielectric constants and extents of hydration characteristic of the proteins. The sensitivity of such a simple external probe to conformational alterations induced by point mutations is unprecedented and provides new insight into key phenomena related to amyloid fibrils: plasticity, polymorphism, propagation of structural features, and structure-function relationships underlying toxicity.

  4. VLT/XSHOOTER & Subaru/MOIRCS Spectroscopy of HUDF-YD3: No Evidence for Lyman-alpha Emission at z=8.55

    CERN Document Server

    Bunker, Andrew J; Wilkins, Stephen M; Stanway, Elizabeth R; Lorenzoni, Silvio; Lacy, Mark; Jarvis, Matt J; Hickey, Samantha

    2013-01-01

    We present spectroscopic observations with VLT/XSHOOTER and Subaru/MOIRCS of a relatively bright Y-band drop-out galaxy in the Hubble Ultra Deep Field, first selected by Bunker et al. (2010), McLure et al. (2010) and Bouwens et al. (2010) to be a likely z~8-9 galaxy on the basis of its colours in the HST ACS and WFC3 images. This galaxy, HUDF.YD3 (also known as UDFy-38135539) has been targetted for VLT/SINFONI integral field spectroscopy by Lehnert et al. (2010), who published a candidate Lyman-alpha emission line at z=8.55 from this source. In our independent spectroscopy using two different infrared spectrographs (5 hours with VLT/XSHOOTER and 11 hours with Subaru/MOIRCS) we are unable to reproduce this line. We do not detect any emission line at the spectral and spatial location reported in Lehnert et al. (2010), despite the expected signal in our combined MOIRCS & XSHOOTER data being 5-sigma. The line emission also seems to be ruled out by the faintness of this object in recently extremely deep F105W ...

  5. HI 21cm emission from the sub-damped Lyman-alpha absorber at z=0.0063 towards PG1216+069

    CERN Document Server

    Chengalur, Jayaram N; Salter, C J; Kanekar, N; Momjian, E; Keeney, B A; Stocke, J T

    2015-01-01

    We present HI 21cm emission observations of the z ~ 0.00632 sub-damped Lyman-alpha absorber (sub-DLA) towards PG1216+069 made using the Arecibo Telescope and the Very Large Array (VLA). The Arecibo 21cm spectrum corresponds to an HI mass of ~ 3.2x10^7 solar masses, two orders of magnitude smaller than that of a typical spiral galaxy. This is surprising since in the local Universe the cross-section for absorption at high HI column densities is expected to be dominated by spirals. The 21cm emission detected in the VLA spectral cube has a low signal-to-noise ratio, and represents only half the total flux seen at Arecibo. Emission from three other sources is detected in the VLA observations, with only one of these sources having an optical counterpart. This group of HI sources appears to be part of complex "W", believed to lie in the background of the Virgo cluster. While several HI cloud complexes have been found in and around the Virgo cluster, it is unclear whether the ram pressure and galaxy harassment proces...

  6. Highly polarized emission in spin resolved photoelectron spectroscopy of alpha-Fe(001)/GaAs(001)

    Energy Technology Data Exchange (ETDEWEB)

    Tobin, James; Yu, Sung Woo; Morton, Simon; Waddill, George; Thompson, Jamie; Neal, James; Spangenberg, Matthais; Shen, T.H.

    2009-05-19

    Highly spin-polarized sources of electrons, Integrated into device design, remain of great interest to the spintronic and magneto-electronic device community Here, the growth of Fe upon GaAs(001) has been studied with photoelectron spectroscopy (PES), including Spin Resolved PES. Despite evidence of atomic level disorder such as intermixing, an over-layer with the spectroscopic signature of alpha-Fe(001), with a bcc real space ordering, Is obtained The results will be discussed in light of the possibility of using such films as a spin-polarized source in device applications.

  7. Deep optical spectroscopy of extended Lyman alpha emission around three radio-quiet z=4.5 quasars

    CERN Document Server

    Courbin, F; Eigenbrod, A; Chelouche, D

    2008-01-01

    We report the first results of a spectroscopic search for Lyman alpha, envelopes around three z=4.5 radio-quiet quasars. Our observational strategy uses the FORS2 spectrograph attached to the UT1 of the Very Large Telescope (VLT) in the multi-slit mode. This allows us to observe simultaneously the quasars and several PSF stars. The spectra of the latter are used to remove the point-like quasar from the data, and to unveil the faint underlying Lyman alpha, envelopes associated with the quasars with unprecedented depth. We clearly detect an envelope around two of the three quasars. These envelopes measure respectively 10" and 13" in extent (i.e. 67 kpc and 87 kpc). This is 5 to 10 times larger than predicted by the models of Haiman & Rees (2001) and up to 100 times fainter. Our observations better agree with models involing a clumpy envelope as in Alam & Miralda-Escude (2002) or Chelouche et al. (2008). We find that the brighter quasars also have the brighter envelopes but that the extend of the envelop...

  8. Decreased cerebral {alpha}4{beta}2* nicotinic acetylcholine receptor availability in patients with mild cognitive impairment and Alzheimer's disease assessed with positron emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Kendziorra, Kai; Meyer, Philipp Mael; Barthel, Henryk; Hesse, Swen; Becker, Georg Alexander; Luthardt, Julia; Schildan, Andreas; Patt, Marianne; Sorger, Dietlind; Seese, Anita; Sabri, Osama [University of Leipzig, Department of Nuclear Medicine, Leipzig (Germany); Wolf, Henrike [University of Leipzig, Department of Psychiatry, Leipzig (Germany); University of Zurich, Department of Old Age Psychiatry and Psychiatry Research, Psychiatric University Hospital (PUK) Zurich, Zurich (Switzerland); Gertz, Herman-Josef [University of Leipzig, Department of Psychiatry, Leipzig (Germany)

    2011-03-15

    Postmortem studies indicate a loss of nicotinic acetylcholine receptor (nAChRs) in Alzheimer's disease (AD). In order to establish whether these changes in the cholinergic system occur at an early stage of AD, we carried out positron emission tomography (PET) with a specific radioligand for the {alpha}4{beta}2* nicotinic acetylcholine receptor ({alpha}4{beta}2* nAChR) in patients with mild to moderate AD and in patients with amnestic mild cognitive impairment (MCI), who have a high risk to progress to AD. Nine patients with moderate AD, eight patients with MCI and seven age-matched healthy controls underwent 2-[{sup 18}F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-[{sup 18}F]FA-85380) PET. After coregistration with individual magnetic resonance imaging the binding potential (BP{sub ND}) of 2-[{sup 18}F]FA-85380 was calculated using either the corpus callosum or the cerebellum as reference regions. PET data were analysed by region of interest analysis and by voxel-based analysis. Both patients with AD and MCI showed a significant reduction in 2-[{sup 18}F]FA-85380 BP{sub ND} in typical AD-affected brain regions. Thereby, the corpus callosum was identified as the most suitable reference region. The 2-[{sup 18}F]FA-85380 BP{sub ND} correlated with the severity of cognitive impairment. Only MCI patients that converted to AD in the later course (n = 5) had a reduction in 2-[{sup 18}F]FA-85380 BP{sub ND}. 2-[{sup 18}F]FA-85380 PET appears to be a sensitive and feasible tool for the detection of a reduction in {alpha}4{beta}2* nAChRs which seems to be an early event in AD. In addition, 2-[{sup 18}F]FA-85380 PET might give prognostic information about a conversion from MCI to AD. (orig.)

  9. ALMA observations of 99 GHz free-free and H40$\\alpha$ line emission from star formation in the centre of NGC 253

    CERN Document Server

    Bendo, G J; D'Cruze, M J; Dickinson, C; Fuller, G A; Muxlow, T W B

    2015-01-01

    We present Atacama Large Millimeter/submillimeter Array observations of 99.02 GHz free-free and H40$\\alpha$ emission from the centre of the nearby starburst galaxy NGC 253. We calculate electron temperatures of 3700-4500 K for the photoionized gas, which agrees with previous measurements. We measure a photoionizing photon production rate of $(3.2\\pm0.2)\\times10^{53}$ s$^{-1}$ and a star formation rate of $1.73\\pm0.12$ M$_\\odot$ yr$^{-1}$ within the central 20$\\times$10 arcsec, which fall within the broad range of measurements from previous millimetre and radio observations but which are better constrained. We also demonstrate that the dust opacities are ~3 dex higher than inferred from previous near-infrared data, which illustrates the benefits of using millimetre star formation tracers in very dusty sources.

  10. A newly discovered DLA and associated Ly-alpha emission in the spectra of the gravitationally lensed quasar UM 673A,B

    CERN Document Server

    Cooke, Ryan; Steidel, Charles C; King, Lindsay J; Rudie, Gwen C; Rakic, Olivera

    2010-01-01

    The sightline to the brighter member of the gravitationally lensed quasar pair UM 673A,B intersects a damped Lyman-alpha system (DLA) at z = 1.62650 which, because of its low redshift, has not been recognised before. Our high quality echelle spectra of the pair, obtained with HIRES on the Keck I telescope, show a drop in neutral hydrogen column density N(H I) by a factor of at least 400 between UM 673A and B, indicating that the DLA's extent in this direction is much less than the 2.7 kpc separation between the two sightlines at z = 1.62650. By reassessing this new case together with published data on other QSO pairs, we conclude that the typical size (radius) of DLAs at these redshifts is R ~ (5 +/- 3) kpc, smaller than previously realised. Highly ionized gas associated with the DLA is more extended, as we find only small differences in the C IV absorption profiles between the two sightlines. Coincident with UM 673B, we detect a weak and narrow Ly-alpha emission line which we attribute to star formation acti...

  11. Evaluation of [{sup 11}C]GB67, a novel radioligand for imaging myocardial {alpha}{sub 1}-adrenoceptors with positron emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Law, M.P.; Osman, S.; Pike, V.W.; Davenport, R.J.; Cunningham, V.J.; Rimoldi, O.; Rhodes, C.G.; Camici, P.G. [MRC Cyclotron Unit, Imperial Coll. School of Medicine, London (United Kingdom); Giardina, D. [Dipt. di Scienze Chimiche, Univ. degli Studi di Camerino, Camerino (Italy)

    2000-01-01

    Dysfunction of the sympathetic nervous system underlies a number of myocardial disorders. Positron emission tomography (PET) offers a way of assessing receptor function non-invasively in humans, but there are no PET radioligands for assessing myocardial {alpha}-adrenoceptors. GB67, a structural and pharmacological analogue of the {alpha}{sub 1}-adrenoceptor antagonist prazosin, was labelled with positron-emitting carbon-11 (t{sub 1/2}=20.4 min) by {sup 11}C-methylation of N-desmethylamido-GB67 (GB99). [{sup 11}C]GB67 was injected intravenously into conscious rats. Serial arterial blood samples were taken. Rats were killed and tissues removed to determine radioactivity. The percentages of unchanged [{sup 11}C]GB67 and its radioactive metabolites in plasma and tissues were assessed by HPLC. Plasma clearance of radioactivity was rapid. Myocardial uptake was maximal at 1-2 min and decreased slowly during 60 min. Predosing with adrenoceptor antagonists demonstrated selectivity for myocardial {alpha}{sub 1}-adrenoceptors. GB67 and prazosin blocked uptake of radioactivity; the non-selective antagonist, phentolamine, partially blocked uptake; the {alpha}{sub 2}-adrenoceptor antagonist, RX 821002, only blocked uptake at high dose and the {beta}-adrenoceptor antagonist, CGP 12177, had no effect. Additionally, injection of prazosin at 20 min after radioligand displaced radioactivity. In vivo competition curves obtained by injecting [{sup 11}C]GB67 with varying amounts of either unlabelled GB67 or its precursor GB99 were fitted to a competitive binding model to provide estimates of the maximum number of binding sites (B{sub max}) and half saturation doses (K) for myocardium. Assuming a tissue protein content of 10%, the values of B{sub max} [{proportional_to}13 pmol.(g tissue){sup -1}] were similar to those [50-170 fmol.(mg protein){sup -1}] reported for myocardial {alpha}{sub 1}-adrenoceptors assessed in vitro. Both GB67 and its precursor GB99 had high affinity for {alpha

  12. Quantification of [{sup 11}C]GB67 binding to cardiac {alpha}{sub 1}-adrenoceptors with positron emission tomography: validation in pigs

    Energy Technology Data Exchange (ETDEWEB)

    Park-Holohan, So-Jin; Turton, David R.; Hume, Susan P. [Hammersmith Hospital, Hammersmith Imanet Ltd., GE HealthCare, Cyclotron Building, London (United Kingdom); Asselin, Marie-Claude [Hammersmith Hospital, Hammersmith Imanet Ltd., GE HealthCare, Cyclotron Building, London (United Kingdom); The University of Manchester, Wolfson Molecular Imaging Centre, Manchester (United Kingdom); Williams, Sharron L.; Camici, Paolo G. [Hammersmith Hospital, MRC Clinical Sciences Centre, Cyclotron Building, London (United Kingdom); Rimoldi, Ornella E. [Hammersmith Hospital, MRC Clinical Sciences Centre, Cyclotron Building, London (United Kingdom); New York Medical College, Cardiovascular Research Institute Department of Medicine, Valhalla, NY (United States)

    2008-09-15

    An increase in human cardiac {alpha}{sub 1}-adrenoceptor ({alpha}{sub 1}-AR) density is associated with various diseases such as myocardial ischemia, congestive heart failure, hypertrophic cardiomyopathy and hypertension. Positron emission tomography (PET) with an appropriate radioligand offers the possibility of imaging receptor function in the normal and diseased heart. [{sup 11}C]GB67, an analogue of prazosin, has been shown in rats to have potential as a PET ligand with high selectivity to {alpha}{sub 1}-AR. However, {alpha}{sub 1}-AR density is up to ten times higher in rat heart compared to that in man. The aim of the present preclinical study was to extend the previous evaluation to a large mammal heart, where the {alpha}{sub 1}-AR density is comparable to man, and to validate a method for quantification before PET studies in man. Seven [{sup 11}C]GB67 PET studies, with weight-adjusted target dose of either 5.29 MBq kg{sup -1} (pilot, test-retest and baseline-predose studies) or 8.22 MBq kg{sup -1} (baseline-displacement studies), were performed in four anaesthetised pigs (39.5 {+-} 3.9 kg). Total myocardial volume of distribution (V{sub T}) was estimated under different pharmacological conditions using compartmental analysis with a radiolabelled metabolite-corrected arterial plasma input function. A maximum possible blocking dose of 0.12 {mu}mol kg{sup -1} of unlabeled GB67 was given 20 min before [{sup 11}C]GB67 administration in the predose study and 45 min after administration of [{sup 11}C]GB67 in the displacement study. In addition, [{sup 15}O]CO (3,000 MBq) and [{sup 15}O]H{sub 2}O, with weight adjusted target dose of 10.57 MBq kg{sup -1}, were also administered for estimation of blood volume recovery (RC) of the left ventricular cavity and myocardial perfusion (MBF), respectively. [{sup 11}C]GB67 V{sub T} values (in ml cm{sup -3}) were estimated to be 24.2 {+-} 5.5 (range, 17.3-31.3), 10.1 (predose) and 11.6 (displacement). MBF did not differ within

  13. Cradle Cap (For Parents)

    Science.gov (United States)

    ... is the common term for seborrheic dermatitis , or seborrhea, which is called dandruff in older kids and ... another factor in the development of cradle cap. Seborrhea happens most often in babies and teenagers. In ...

  14. Evaluation of [O-methyl-{sup 11}C]RS-15385-197 as a positron emission tomography radioligand for central {alpha}{sub 2}-adrenoceptors

    Energy Technology Data Exchange (ETDEWEB)

    Hume, S.P.; Hirani, E.; Opacka-Juffry, J.; Osman, S.; Myers, R.; Gunn, R.N.; McCarron, J.A.; Pike, V.W. [MRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, London (United Kingdom); Clark, R.D. [Roche Bioscience, Pharma Division, Palo Alto, CA (United States); Melichar, J.; Nutt, D.J. [Psychopharmacology Unit, School of Medical Science, University of Bristol, Bristol (United Kingdom)

    2000-05-01

    Carbon-11 labelled RS-15385-197 and its ethylsulphonyl analogue, RS-79948-197, were evaluated in rats as potential radioligands to image central {alpha}{sub 2}-adrenoceptors in vivo. The biodistributions of both compounds were comparable with that obtained in an earlier study using tritiated RS-79948-197 and were consistent with the known localisation of {alpha}{sub 2}-adrenoceptors. The maximal signals (total to non-specific binding) were, however, reduced, in the order [{sup 11}C]RS-79948-197 < [{sup 11}C]RS-15385-197 < [{sup 3}H]RS-79948-197, primarily due to the difference in radiolabel position (O-methyl for carbon-11 compared with S-ethyl for tritium). This resulted in the in-growth of radiolabelled metabolites in plasma, which, in turn, contributed to the non-specific component of brain radioactivity. Nonetheless, the signal ratio of {proportional_to}5 for a receptor-dense tissue compared with the receptor-sparse cerebellum, at 90-120 min after radioligand injection, encouraged the development of [O-methyl-{sup 11}C]RS-15385-197 for human positron emission tomography (PET). Unfortunately, in two human PET scans (each of 90 min), brain extraction of the radioligand was minimal, with volumes of distribution more than an order of magnitude lower than that measured in rats. Following intravenous injection, radioactivity was retained in plasma and metabolism of the radiolabelled compound was very low. Retrospective measurements of in vitro plasma protein binding and in vivo brain uptake index (BUI) in rats demonstrated a higher protein binding of the radioligand in human compared with rat plasma and a lower BUI in the presence of human plasma. It is feasible that a higher affinity of RS-15385-197 for human plasma protein compared with receptor limited the transport of the radioligand. Although one of the PET scans showed a slight heterogeneity in biodistribution of radioactivity which was consistent with the known localisation of {alpha}{sub 2}-adrenoceptors in

  15. Noninvasive visualization and quantification of tumor {alpha}{sub V{beta}3} integrin expression using a novel positron emission tomography probe, {sup 64}Cu-cyclam-RAFT-c(-RGDfK-){sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Zhao-Hui [Molecular Imaging Center, National Institute of Radiological Sciences, Chiba 263-8555 (Japan); Furukawa, Takako, E-mail: tfuru@nirs.go.j [Molecular Imaging Center, National Institute of Radiological Sciences, Chiba 263-8555 (Japan); Biomedical Imaging Research Center, University of Fukui, Fukui 910-1193 (Japan); Galibert, Mathieu; Boturyn, Didier [Departement de Chimie Moleculaire, UMR 5250, CNRS-Universite Joseph Fourier, 38041 Grenoble Cedex 9 (France); Coll, Jean-Luc [INSERM U823, Institut Albert Bonniot and Universite Joseph Fourier, 38706 La Tronche Cedex, Grenoble (France); Fukumura, Toshimitsu; Saga, Tsuneo [Molecular Imaging Center, National Institute of Radiological Sciences, Chiba 263-8555 (Japan); Dumy, Pascal [Departement de Chimie Moleculaire, UMR 5250, CNRS-Universite Joseph Fourier, 38041 Grenoble Cedex 9 (France); Fujibayashi, Yasuhisa [Molecular Imaging Center, National Institute of Radiological Sciences, Chiba 263-8555 (Japan); Biomedical Imaging Research Center, University of Fukui, Fukui 910-1193 (Japan)

    2011-05-15

    Introduction: The {alpha}{sub V{beta}3} integrin is a well-known transmembrane receptor involved in tumor invasion, angiogenesis and metastasis. Our aim was to evaluate a novel positron emission tomography (PET) probe, {sup 64}Cu-cyclam-RAFT-c(-RGDfK-){sub 4}, for noninvasive visualization and quantification of {alpha}{sub V{beta}3} integrin expression. Methods: RAFT-c(-RGDfK-){sub 4}, a tetrameric cyclic Arg-Gly-Asp (RGD)-based peptide, was conjugated with a bifunctional chelator, 1,4,8,11-tetraazacyclotetradecane (cyclam), radiolabeled with the positron emitter {sup 64}Cu and evaluated in vitro by cell binding and competitive inhibition assays and in vivo by biodistribution and receptor blocking studies, and PET imaging. The following cell lines, human embryonic kidney HEK293({beta}{sub 1}) [{alpha}{sub V{beta}3}-negative] and HEK293({beta}{sub 3}) [{alpha}{sub V{beta}3}-overexpressing] and human glioblastoma U87MG [naturally expressing {alpha}{sub V{beta}3}], together with their subcutaneous xenografts in athymic nude mice, were used for the present study. The expression levels of {alpha}{sub V{beta}3} on these cell lines and tumor xenografts were analyzed by flow cytometry and sodium dodecyl sulfate-polyacrylamide gel electrophoresis/autoradiography, respectively. Results: {sup 64}Cu-cyclam-RAFT-c(-RGDfK-){sub 4} demonstrated the in vitro and in vivo specificity for the {alpha}{sub V{beta}3} integrin and displayed rapid blood clearance, predominantly renal excretion and low uptake in nontumor tissues. Tumor uptake of {sup 64}Cu-cyclam-RAFT-c(-RGDfK-){sub 4} (3 h postinjection) in HEK293({beta}{sub 3}) (high levels of {alpha}{sub V{beta}3}), U87MG (moderate levels of {alpha}{sub V{beta}3}) and HEK293({beta}{sub 1}) (undetectable levels of {alpha}{sub V{beta}3}) tumors was 9.35%{+-}1.19%, 3.46%{+-}0.45% and 1.18%{+-}0.30% injected dose per gram, respectively, with a strong and positive correlation with the tumor {alpha}{sub V{beta}3} expression levels

  16. A hard ionizing spectrum in z=3-4 Ly-alpha emitters with intense [OIII] emission: Analogs of galaxies in the reionization era?

    CERN Document Server

    Nakajima, Kimihiko; Iwata, Ikuru; Inoue, Akio; Kusakabe, Haruka; Ouchi, Masami; Robertson, Brant

    2016-01-01

    We present Keck/MOSFIRE spectra of the diagnostic nebular emission lines [OIII]5007,4959, [OII]3727, and H-beta for a sample of 15 redshift z=3.1-3.7 Ly-alpha emitters (LAEs) and Lyman break galaxies (LBGs). In conjunction with spectra from other surveys, we confirm earlier indications that LAEs have a much higher [OIII]/[OII] line ratio than is seen in similar redshift LBGs. By comparing their distributions on a [OIII]/[OII] versus R23 diagram, we demonstrate that this difference cannot arise solely because of their lower metallicities but most likely is due to a harder ionizing spectrum. Using measures of H-beta and recombination theory, we demonstrate, for a subset of our LAEs, that xi_ion - the number of Lyman continuum photons per UV luminosity - is indeed 0.2-0.5 dex larger than for typical LBGs at similar redshifts. Using photoionization models we estimate the effect this would have on both [OIII]/[OII] and R23 and conclude such a hard spectrum can only partially explain such intense line emission. The...

  17. Imaging of soft-tissue tumors using L-3-[iodine-123]iodo-alpha-methyl-tyrosine single photon emission computed tomography: comparison with proliferative and mitotic activity, cellularity, and vascularity.

    NARCIS (Netherlands)

    Jager, P L; Plaat, B E; Vries, E G de; Molenaar, W M; Vaalburg, W; Piers, D A; Hoekstra, H J

    2000-01-01

    The radiolabeled amino acid L-3-[123I]-iodo-alpha-methyltyrosine (IMT) is a new tumor tracer that accumulates in many tumors and is suitable for single photon emission computed tomography (SPECT) imaging. Using IMT SPECT, we studied 32 patients with a soft-tissue tumor suspected to be a soft-tissue

  18. [OIII] emission line as a tracer of star-forming galaxies at high redshifts: Comparison between H$\\alpha$ and [OIII] emitters at $z$=2.23 in HiZELS

    CERN Document Server

    Suzuki, T L; Sobral, D; Khostovan, A A; Hayashi, M; Shimakawa, R; Koyama, Y; Tadaki, K -i; Tanaka, I; Minowa, Y; Yamamoto, M; Smail, I; Best, P N

    2016-01-01

    We investigate the properties of $z$=2.23 H$\\alpha$ and [OIII]$\\lambda$5007 emitters using the narrow-band-selected samples obtained from the High-$z$ Emission Line Survey (HiZELS: Sobral et al. 2013). We construct two samples of the H$\\alpha$ and [OIII] emitters and compare their integrated physical properties. We find that the distribution of stellar masses, dust extinction, star formation rates (SFRs), and specific SFRs, is not statistically different between the two samples. When we separate the full galaxy sample into three subsamples according to the detections of the H$\\alpha$ and/or [OIII] emission lines, most of the sources detected with both H$\\alpha$ and [OIII] show ${\\rm log(sSFR_{UV})}$$\\gtrsim$-9.5. The comparison of the three subsamples suggests that sources with strong [OIII] line emission tend to have the highest star-forming activity out all galaxies that we study. We argue that the [OIII] emission line can be used as a tracer of star-forming galaxies at high redshift, and that it is especia...

  19. Measurement and simulation of passive fast-ion D-alpha emission from the DIII-D tokamak

    Science.gov (United States)

    Bolte, Nathan G.; Heidbrink, William W.; Pace, David; Van Zeeland, Michael; Chen, Xi

    2016-11-01

    Spectra of passive fast-ion D-alpha (FIDA) light from beam ions that charge exchange with background neutrals are measured and simulated. The fast ions come from three sources: ions that pass through the diagnostic sightlines on their first full orbit, an axisymmetric confined population, and ions that are expelled into the edge region by instabilities. A passive FIDA simulation (P-FIDASIM) is developed as a forward model for the spectra of the first-orbit fast ions and consists of an experimentally-validated beam deposition model, an ion orbit-following code, a collisional-radiative model, and a synthetic spectrometer. Model validation consists of the simulation of 86 experimental spectra that are obtained using 6 different neutral beam fast-ion sources and 13 different lines of sight. Calibrated spectra are used to estimate the neutral density throughout the cross-section of the tokamak. The resulting 2D neutral density shows the expected increase toward each X-point with average neutral densities of 8× {{10}9}~\\text{c}{{\\text{m}}-3} at the plasma boundary and 1× {{10}11}~\\text{c}{{\\text{m}}-3} near the wall. Fast ions that are on passing orbits are expelled by the sawtooth instability more readily than trapped ions. In a sample discharge, approximately 1% of the fast-ion population is ejected into the high neutral density region per sawtooth crash.

  20. Comparison of U.S. Environmental Protection Agency's CAP88 PC Versions 3.0 and 4.0.

    Science.gov (United States)

    Jannik, Tim; Farfan, Eduardo B; Dixon, Ken; Newton, Joseph; Sailors, Christopher; Johnson, Levi; Moore, Kelsey; Stahman, Richard

    2015-08-01

    The Savannah River National Laboratory (SRNL) with the assistance of Georgia Regents University, completed a comparison of the U.S. Environmental Protection Agency's (U.S. EPA) environmental dosimetry code CAP88 PC V3.0 with the recently developed V4.0. CAP88 is a set of computer programs and databases used for estimation of dose and risk from radionuclide emissions to air. At the U.S. Department of Energy's Savannah River Site, CAP88 is used by SRNL for determining compliance with U.S. EPA's National Emission Standards for Hazardous Air Pollutants (40 CFR 61, Subpart H) regulations. Using standardized input parameters, individual runs were conducted for each radionuclide within its corresponding database. Some radioactive decay constants, human usage parameters, and dose coefficients changed between the two versions, directly causing a proportional change in the total effective dose. A detailed summary for select radionuclides of concern at the Savannah River Site (60Co, 137Cs, 3H, 129I, 239Pu, and 90Sr) is provided. In general, the total effective doses will decrease for alpha/beta emitters because of reduced inhalation and ingestion rates in V4.0. However, for gamma emitters, such as 60Co and 137Cs, the total effective doses will increase because of changes U.S. EPA made in the external ground shine calculations.

  1. Alpha Thalassemia

    Science.gov (United States)

    Alpha Thalassemia Physicians often mistake alpha thalassemia trait for iron deficiency anemia and incorrectly prescribe iron supplements that have no effect 1 on the anemia. αα αα Normal alpha ...

  2. Anion induced modulation of self-assembly and optical properties in urea end-capped oligo(p-phenylenevinylene)s.

    Science.gov (United States)

    Varghese, Reji; George, Subi J; Ajayaghosh, Ayyappanpillai

    2005-02-01

    The non-emissive supramolecular assembly of urea end-capped oligo(p-phenylenevinylene) flourophores turned strongly emissive in the presence of tetrabutylammonium flouride which has implications in the anion controlled design of supramolecular architectures with tunable emission properties.

  3. Thermal Iron K and Alpha: Line Emission from the X-Ray Binary GX 339-4

    Science.gov (United States)

    Xu, Y. D.; Zhang, S. N.; Zhang, X. L.; Liu, D. B.; Chen, L.; Xu, H. G.; You, J. H.

    2003-01-01

    The accretion rate of the black hole candidate X-ray binary GX 339-4 in the 'off' state is low, and an advection dominated accretion flow (ADAF) is present. Hydrogen-like and helium-like iron Kbalpha; emission lines at 6.7 and 6.95 keV from hot plasma of ADAF can be produced by recombination-cascade processes with moderately high intensities, which are markedly distinguished from the fluorescent iron Kα line at approximately 6.4 keV. We show that the observational features of GX 339-4 can be explained by the ADAF model, if the iron abundance is more than 10 times the solar value, though the reason for such a high abundance is still unclear. We suggest that the increase of the accretion rate makes GX 339-4 change from off, low, intermediate, to high and very high states, and the line center of iron Kbalpha; will therefore shift from approximately 6.83 to approximately 6.4 keV, i.e. to the fluorescent disc-line, since the disappearance of the ADAF due to its high accretion rate.

  4. The Development of Replicated Optical Integral Field Spectrographs and their Application to the Study of Lyman-alpha Emission at Moderate Redshifts

    Science.gov (United States)

    Chonis, Taylor Steven

    In the upcoming era of extremely large ground-based astronomical telescopes, the design of wide-field spectroscopic survey instrumentation has become increasingly complex due to the linear growth of instrument pupil size with telescope diameter for a constant spectral resolving power. The upcoming Visible Integral field Replicable Unit Spectrograph (VIRUS), a baseline array of 150 copies of a simple integral field spectrograph that will be fed by 3:36 x 104 optical fibers on the upgraded Hobby-Eberly Telescope (HET) at McDonald Observatory, represents one of the first uses of large-scale replication to break the relationship between instrument pupil size and telescope diameter. By dividing the telescope's field of view between a large number of smaller and more manageable instruments, the total information grasp of a traditional monolithic survey spectrograph can be achieved at a fraction of the cost and engineering complexity. To highlight the power of this method, VIRUS will execute the HET Dark Energy Experiment (HETDEX) and survey & 420 degrees2 of sky to an emission line flux limit of ˜ 10-17 erg s-1 cm -2 to detect ˜ 106 Lyman-alpha emitting galaxies (LAEs) as probes of large-scale structure at redshifts of 1:9 ProQuest.).

  5. Study of the {sup 18}F(p,{alpha}){sup 15}O reaction by transfer reaction for application to {gamma}-ray emission from Novae; Etude de la reaction {sup 18}F(p,{alpha}){sup 15}O par reaction de transfert pour application a l'emission {gamma} des Novae

    Energy Technology Data Exchange (ETDEWEB)

    Sereville, N. de

    2003-12-15

    The gamma emission from novae at/or below 511 keV is due to the annihilation of the positrons produced in the beta + decay of F{sup 18}. The interpretation of this emission through observations made by the Integral satellite for instance, requires a good knowledge of F{sup 18} nucleosynthesis. The reaction rate of the F{sup 18}(p,{alpha})O{sup 15} is the least known because of 2 resonances corresponding to the levels 6.419 and 6.449 MeV of Ne{sup 19} whose proton widths are completely unknown. We have determined these proton widths via the study of one-nucleon transfer reaction D(F{sup 18},p{alpha})N{sup 15} populating equivalent levels in F{sup 19}. We have used a 14 MeV F{sup 18} radioactive beam on a CD{sub 2} target for inverse kinematics studies and the multi-track silicon detector LEDA. A DWBA (Distorted Wave Bound Approximation) has enabled us to determine the proton width of both resonances and has showed that they have an impact in the calculation of the reaction rate. A thorough study of the remaining uncertainties of the reaction rate has been undertaken, particularly for those concerning interferences between these resonances and a higher resonance of Ne{sup 19}. The reaction rate that we have obtained is very similar to the previous rate used but now it rests on a more solid basis.

  6. Assessing the value of price caps and floors

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    This publication assesses the long-term economic and climatic effects of introducing price caps and price floors in hypothetical global climate change mitigation policy. Based on emission trends, abatement costs and equilibrium climate sensitivity from IPCC and IEA reports, this quantitative analysis confirms that price caps could significantly reduce economic uncertainty. This uncertainty stems primarily from unpredictable economic growth and energy prices, and ultimately unabated emission trends. In addition, the development of abatement technologies is uncertain. Furthermore,this analysis shows that rigid targets may entail greater economic risks with little or no comparative advantage for the climate. More ambitious emission objectives, combined with price caps and price floors, could still entail significantly lower expected costs while driving similar, or even slightly better, climatic outcomes in probabilistic terms.

  7. Hepatic lesions and hemolysis following administration of 3. cap alpha. , 7. cap alpha. , 12. cap alpha. -trihydroxy-5. beta. -cholestan-26-oyl taurine to rats

    Energy Technology Data Exchange (ETDEWEB)

    Hanson, R.F. (Univ. of Minnesota, Minneapolis); Williams, G.C.; Hachey, D.; Sharp, H.L.

    1977-09-01

    Patients with a metabolic block in the conversion of THCA into cholic acid develop cirrhosis and hemolysis, and die of hepatic failure. In these patients, THCA is largely conjugated to taurine (tauro-THCA) and excreted instead of being converted into cholic acid. In the present study, the effects of tauro-THCA on hemolysis, bile flow, and hepatic morphology were evaluated in bile fistula rats. All rats infused with tauro-THCA at rates of 0.25, 0.50 or 0.75 ..mu..mol/min developed hemolysis with hemoglobinuria. A direct toxic effect of tauro-THCA on washed human red blood cell membranes was demonstrated at a concentration of 8 x 10/sup -4/ M. Liver biopsy sections from rats infused for a 2 hr period with tauro-THCA were examined by electron microscopy and showed dilation of the rough endoplasmic reticulum and distortion of mitochondrial membranes. Cholestasis was not induced, since tauro-THCA actually caused a greater choleretic response for a given rate of bile salt excretion than did taurocholate. This study raises the possibility that the clinical liver disease seen in patients with a metabolic block in the conversion of THCA into cholic acid may be caused by tauro-THCA.

  8. Saltstone Clean Cap Formulation

    Energy Technology Data Exchange (ETDEWEB)

    Langton, C

    2005-04-22

    The current operation strategy for using Saltstone Vault 4 to receive 0.2 Ci/gallon salt solution waste involves pouring a clean grout layer over the radioactive grout prior to initiating pour into another cell. This will minimize the radiating surface area and reduce the dose rate at the vault and surrounding area. The Clean Cap will be used to shield about four feet of Saltstone poured into a Z-Area vault cell prior to moving to another cell. The minimum thickness of the Clean Cap layer will be determined by the cesium concentration and resulting dose levels and it is expected to be about one foot thick based on current calculations for 0.1 Ci Saltstone that is produced in the Saltstone process by stabilization of 0.2 Ci salt solution. This report documents experiments performed to identify a formulation for the Clean Cap. Thermal transient calculations, adiabatic temperature rise measurements, pour height, time between pour calculations and shielding calculations were beyond the scope and time limitations of this study. However, data required for shielding calculations (composition and specific gravity) are provided for shielding calculations. The approach used to design a Clean Cap formulation was to produce a slurry from the reference premix (10/45/45 weight percent cement/slag/fly ash) and domestic water that resembled as closely as possible the properties of the Saltstone slurry. In addition, options were investigated that may offer advantages such as less bleed water and less heat generation. The options with less bleed water required addition of dispersants. The options with lower heat contained more fly ash and less slag. A mix containing 10/45/45 weight percent cement/slag/fly ash with a water to premix ratio of 0.60 is recommended for the Clean Cap. Although this mix may generate more than 3 volume percent standing water (bleed water), it has rheological, mixing and flow properties that are similar to previously processed Saltstone. The recommended

  9. Structure of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum.

    Science.gov (United States)

    Ksiazek, Dorota; Brandstetter, Hans; Israel, Lars; Bourenkov, Gleb P; Katchalova, Galina; Janssen, Klaus-Peter; Bartunik, Hans D; Noegel, Angelika A; Schleicher, Michael; Holak, Tad A

    2003-09-01

    Cyclase-associated proteins (CAPs) are widely distributed and highly conserved proteins that regulate actin remodeling in response to cellular signals. The N termini of CAPs play a role in Ras signaling and bind adenylyl cyclase; the C termini bind to G-actin and thereby alter the dynamic rearrangements of the microfilament system. We report here the X-ray structure of the core of the N-terminal domain of the CAP from Dictyostelium discoideum, which comprises residues 51-226, determined by a combination of single isomorphous replacement with anomalous scattering (SIRAS). The overall structure of this fragment is an alpha helix bundle composed of six antiparallel helices. Results from gel filtration and crosslinking experiments for CAP(1-226), CAP(255-464), and the full-length protein, together with the CAP N-terminal domain structure and the recently determined CAP C-terminal domain structure, provide evidence that the functional structure of CAP is multimeric.

  10. Facile hydrothermal synthesis of alpha manganese sesquioxide ({alpha}-Mn{sub 2}O{sub 3}) nanodumb-bells: Structural, magnetic, optical and photocatalytic properties

    Energy Technology Data Exchange (ETDEWEB)

    Gnanam, S., E-mail: gnanam.nanoscience@gmail.com [Department of Physics, Presidency College, Chennai 600005, Tamilnadu (India); Rajendran, V. [Department of Physics, Presidency College, Chennai 600005, Tamilnadu (India)

    2013-02-15

    Highlights: Black-Right-Pointing-Pointer {alpha}-Mn{sub 2}O{sub 3} nanoparticles sizes of 35-42 nm have been prepared by hydrothermal process. Black-Right-Pointing-Pointer Shapes of {alpha}-Mn{sub 2}O{sub 3}: Dumb-bell, Cauliflower, spherical with rod, spherical with wires. Black-Right-Pointing-Pointer The strong UV emission can be attributed to high purity and perfect crystallinity. Black-Right-Pointing-Pointer Photocatalytic activity of {alpha}-Mn{sub 2}O{sub 3} was studied by degradation of Remazol red B dye. - Abstract: Nanometer scale cubic bixbyite {alpha}-Mn{sub 2}O{sub 3} has been synthesized by a facile hydrothermal method, at a temperature of 450 Degree-Sign C in the presence of various surfactants. The X-ray diffraction (XRD) analysis shows that the average crystallite size of the sample is {approx}35-42 nm. The shapes of the {alpha}-Mn{sub 2}O{sub 3} nanoparticles include: Dumb-bell-like (anionic surfactant), Cauliflower-like (nonionic surfactant), spherical with rods (cationic surfactant) and spherical with wires (surface modifier). The shapes of {alpha}-Mn{sub 2}O{sub 3} nanoparticles depend on the type of surfactant used in the synthesis. The magnetic property of the anionic surfactant assisted sample was primarily studied, using the vibrating sample magnetometer (VSM). The optical absorption spectra confirmed the effectiveness of the selected capping agents, as the anionic capped {alpha}-Mn{sub 2}O{sub 3} colloids absorbed at shorter wavelength than the other agents, indicating a much smaller crystallite size. The property of strong UV emissions may be attributed to the high purity and perfect crystallinity of the as-prepared {alpha}-Mn{sub 2}O{sub 3}. The surfactants-assisted catalyst was tested for its photocatalytic activity towards the photodegradation of the harmful organic dye Remazol Red B, using a multilamp photo reactor. Possible formation mechanisms have also been proposed for the as-synthesized anionic surfactant assisted samples.

  11. Laser assisted {alpha} decay

    Energy Technology Data Exchange (ETDEWEB)

    Castaneda Cortes, Hector Mauricio

    2012-02-01

    Excited or short-lived nuclei often decay by emitting alpha particles that are assumed to be preformed inside the nucleus and confined in the nuclear potential well. In this picture, {alpha} decay refers to the tunneling of the alpha particle through the potential barrier. In this thesis we investigate for the first time how strong laser fields can assist the tunneling of the alpha particle and thus influence the nuclear decay. Generally speaking, laser-assisted {alpha} decay can be described as laser-assisted tunneling of a quasistationary state, i.e, a slowly decaying state. Our theoretical treatment is developed starting from the complex trajectory formulation of the well-known strong-field approximation used to describe laser-induced ionization. We extend this formulation and develop a method to treat the decay of quasistationary states. The effect of both static and optical and X-ray monochromatic fields on the lifetimes and {alpha}-particle emission spectra are investigated for a number of {alpha}-emitting nuclei. We find that even at strong intensities, the laser-induced acceleration of the {alpha} decay is negligible, ranging from a relative modification in the decay rate of 10{sup -3} for static fields of electric field strengths of 10{sup 15} V/m, to 10{sup -8} for strong optical fields with intensities of 10{sup 22} W/cm{sup 2}, and to 10{sup -6} for strong X-ray fields with laser intensities around 10{sup 24} W/cm{sup 2}. However, the effect of the external field is visible in the spectrum of emitted alpha particles, leading in the case of optical fields even to rescattering phenomena for intensities approaching 6 x 10{sup 22} W/cm{sup 2}. The dynamics of the alpha particle in laser fields of intensities below the rescattering limit is investigated.

  12. Polar Cap Retreat

    Science.gov (United States)

    2004-01-01

    13 August 2004 This red wide angle Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a view of the retreating seasonal south polar cap in the most recent spring in late 2003. Bright areas are covered with frost, dark areas are those from which the solid carbon dioxide has sublimed away. The center of this image is located near 76.5oS, 28.2oW. The scene is large; it covers an area about 250 km (155 mi) across. The scene is illuminated by sunlight from the upper left.

  13. A high spatial resolution X-ray and H-alpha study of hot gas in the halos of star-forming disk galaxies. I. Spatial and spectral properties of the diffuse X-ray emission

    CERN Document Server

    Strickland, D K; Colbert, E J M; Hoopes, C G; Weaver, K A

    2003-01-01

    We present arcsecond resolution Chandra X-ray and ground-based optical H-alpha imaging of a sample of ten edge-on star-forming disk galaxies (seven starburst and three ``normal'' spiral galaxies), a sample which covers the full range of star-formation intensity found in disk galaxies. We use the unprecedented spatial resolution of the Chandra X-ray observatory to robustly remove point sources, and hence obtain the X-ray properties of the diffuse thermal emission alone. The X-ray observations are combined with comparable-resolution H-alpha and R-band imaging, and presented as a mini-atlas of images on a common spatial and surface brightness scale. The vertical distribution of the halo-region X-ray surface brightness is best described as an exponential, with the observed scale heights lying in the range H_eff = 2 -- 4 kpc. The ACIS X-ray spectra of extra-planar emission from all these galaxies can be fit with a common two-temperature spectral model with an enhanced alpha-to-iron element ratio. This is consisten...

  14. All-sky Observational Evidence for An Inverse Correlation between Dust Temperature and Emissivity Spectral Index

    CERN Document Server

    Liang, Z; Gold, B

    2012-01-01

    We show that a one-component variable-emissivity-spectral-index model (the free-{\\alpha} model) provides more physically motivated estimates of dust temperature at the Galactic polar caps than one- or two-component fixed-emissivity-spectral-index models (fixed-{\\alpha} models) for interstellar dust thermal emission at far-infrared and millimeter wavelengths. For the comparison we have fit all-sky one-component dust models with fixed or variable emissivity spectral index to a new and improved version of the 210-channel dust spectra from the COBE-FIRAS, the 100 - 240 {\\mu}m maps from the COBE-DIRBE and the 94 GHz dust map from the WMAP. The best model, the free-{\\alpha} model, is well constrained by data at 60-3000 GHz over 86 per cent of the total sky area. It predicts dust temperature (Tdust) to be 13.7-22.7 ({\\pm}1.3) K, the emissivity spectral index ({\\alpha}) to be 1.2 - 3.1 ({\\pm}0.3) and the optical depth ({\\tau}) to range 0.6 - 46 {\\times} 10^(-5) with a 23 per cent uncertainty. Using these estimates, w...

  15. Synthesis and positron emission tomography studies of C-11-labeled isotopomers and metabolites of GTS-21, a partial {alpha}7 nicotinic cholinergic agonist drug

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung Won [Medical Department, Brookhaven National Laboratory, Upton, NY 11973 (United States) and Department of Chemistry, State University of New York at Stony Brook, Stony Brook, NY 11794-3400 (United States)]. E-mail: swkim@bnl.gov; Ding Yushin [Department of Chemistry, State University of New York at Stony Brook, Stony Brook, NY 11794-3400 (United States); Department of Radiology, Yale University School of Medicine, New Haven, CT 06520-8048 (United States); Alexoff, David [Medical Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); Patel, Vinal [Medical Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); Logan, Jean [Medical Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); Lin, K.-S. [Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213 (United States); Shea, Colleen [Medical Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); Muench, Lisa [Medical Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); Xu Youwen [Medical Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); Carter, Pauline [Medical Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); King, Payton [Medical Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); Constanzo, Jasmine R. [Department of Chemistry, Fordham University, Bronx, NY 10458 (United States); Ciaccio, James A. [Department of Chemistry, Fordham University, Bronx, NY 10458 (United States); Fowler, Joanna S. [Medical Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); Department of Chemistry, State University of New York at Stony Brook, Stony Brook, NY 11794-3400 (United States); Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 (United States)

    2007-07-15

    Introduction: (3E)-3-[(2,4-dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-bipyridine (GTS-21), a partial {alpha}7 nicotinic acetylcholine receptor agonist drug, has recently been shown to improve cognition in schizophrenia and Alzheimer's disease. One of its two major demethylated metabolites, 4-OH-GTS-21, has been suggested to contribute to its therapeutic effects. Methods: We labeled GTS-21 in two different positions with carbon-11 ([2-methoxy-{sup 11}C]GTS-21 and [4-{sup 11}C]GTS-21) along with two corresponding demethylated metabolites ([2-methoxy-{sup 11}C]4-OH-GTS-21 and [4-methoxy-{sup 11}C]2-OH-GTS-21) for pharmacokinetic studies in baboons and mice with positron emission tomography (PET). Results: Both [2-{sup 11}C]GTS-21 and [4-methoxy-{sup 11}C]GTS-21 showed similar initial high rapid uptake in baboon brain, peaking from 1 to 3.5 min (0.027-0.038%ID/cc) followed by rapid clearance (t {sub 1/2}<15 min), resulting in low brain retention by 30 min. However, after 30 min, [2-methoxy-{sup 11}C]GTS-21 continued to clear while [4-methoxy-{sup 11}C]GTS-21 plateaued, suggesting the entry of a labeled metabolite into the brain. Comparison of the pharmacokinetics of the two labeled metabolites confirmed expected higher brain uptake and retention of [4-methoxy-{sup 11}C]2-OH-GTS-21 (the labeled metabolite of [4-methoxy-{sup 11}C]GTS-21) relative to [2-methoxy-{sup 11}C]4-OH-GTS-21 (the labeled metabolite of [2-methoxy-{sup 11}C]GTS-21), which had negligible brain uptake. Ex vivo studies in mice showed that GTS-21 is the major chemical form in the mouse brain. Whole-body dynamic PET imaging in baboon and mouse showed that the major route of excretion of C-11 is through the gallbladder. Conclusions: The major findings are as follows: (a) extremely rapid uptake and clearance of [2-methoxy-{sup 11}C]GTS-21 from the brain, which may need to be considered in developing optimal dosing of GTS-21 for patients, and (b) significant brain uptake of 2-OH-GTS-21

  16. CARMIL is a bona fide capping protein interactant.

    Science.gov (United States)

    Remmert, Kirsten; Olszewski, Thomas E; Bowers, M Blair; Dimitrova, Mariana; Ginsburg, Ann; Hammer, John A

    2004-01-23

    CARMIL, also known as Acan 125, is a multidomain protein that was originally identified on the basis of its interaction with the Src homology 3 (SH3) domain of type I myosins from Acanthamoeba. In a subsequent study of CARMIL from Dictyostelium, pull-down assays indicated that the protein also bound capping protein and the Arp2/3 complex. Here we present biochemical evidence that Acanthamoeba CARMIL interacts tightly with capping protein. In biochemical preparations, CARMIL copurified extensively with two polypeptides that were shown by microsequencing to be the alpha- and beta-subunits of Acanthamoeba capping protein. The complex between CARMIL and capping protein, which is readily demonstratable by chemical cross-linking, can be completely dissociated by size exclusion chromatography at pH 5.4. Analytical ultracentrifugation, surface plasmon resonance and SH3 domain pull-down assays indicate that the dissociation constant of capping protein for CARMIL is approximately 0.4 microm or lower. Using CARMIL fusion proteins, the binding site for capping protein was shown to reside within the carboxyl-terminal, approximately 200 residue, proline-rich domain of CARMIL. Finally, chemical cross-linking, analytical ultracentrifugation, and rotary shadowed electron microscopy revealed that CARMIL is asymmetric and that it exists in a monomer dimer equilibrium with an association constant of 1.0 x 10(6) m(-1). Together, these results indicate that CARMIL self-associates and interacts with capping protein with affinities that, given the cellular concentrations of the proteins ( approximately 1 and 2 microm for capping protein and CARMIL, respectively), indicate that both activities should be physiologically relevant.

  17. Novel Multipin Electrode Cap System for Dry Electroencephalography.

    Science.gov (United States)

    Fiedler, P; Pedrosa, P; Griebel, S; Fonseca, C; Vaz, F; Supriyanto, E; Zanow, F; Haueisen, J

    2015-09-01

    Current usage of electroencephalography (EEG) is limited to laboratory environments. Self-application of a multichannel wet EEG caps is practically impossible, since the application of state-of-the-art wet EEG sensors requires trained laboratory staff. We propose a novel EEG cap system with multipin dry electrodes overcoming this problem. We describe the design of a novel 24-pin dry electrode made from polyurethane and coated with Ag/AgCl. A textile cap system holds 97 of these dry electrodes. An EEG study with 20 volunteers compares the 97-channel dry EEG cap with a conventional 128-channel wet EEG cap for resting state EEG, alpha activity, eye blink artifacts and checkerboard pattern reversal visual evoked potentials. All volunteers report a good cap fit and good wearing comfort. Average impedances are below 150 kΩ for 92 out of 97 dry electrodes, enabling recording with standard EEG amplifiers. No significant differences are observed between wet and dry power spectral densities for all EEG bands. No significant differences are observed between the wet and dry global field power time courses of visual evoked potentials. The 2D interpolated topographic maps show significant differences of 3.52 and 0.44% of the map areas for the N75 and N145 VEP components, respectively. For the P100 component, no significant differences are observed. Dry multipin electrodes integrated in a textile EEG cap overcome the principle limitations of wet electrodes, allow rapid application of EEG multichannel caps by non-trained persons, and thus enable new fields of application for multichannel EEG acquisition.

  18. Development of Gasless Pyrotechnic Cap

    Science.gov (United States)

    1980-05-01

    beam cathode ray oscillo- scope. The caps were ignited by removing the safety pin . This also triggered the oscilloscope. The change in pressure inside...sensitivity. STRIKER SAFETY PIN PERCUSSION CAP FIXED VOLUME / ;PRESSURE TRANSDUCER TO C.R.O. FIG. 8 - Device used to determine pressure time

  19. Diagram X-ray emission spectra of a hollow atom: the Kh alpha1,2 and Kh beta1,3 hypersatellites of Fe.

    Science.gov (United States)

    Diamant, R; Huotari, S; Hämäläinen, K; Sharon, R; Kao, C C; Deutsch, M

    2003-11-07

    High-resolution Fe K(h) beta(1,3) and K(h) alpha(1,2) hypersatellite spectra were measured, using monochromatized synchrotron radiation photoexcitation. The lines' energies, splitting, excitation thresholds, and the K(h) alpha(1)/K(h) alpha(2) intensity ratio were derived with high accuracy. Having both spectra, not hitherto available for any atom with high resolution, allows separating out the energy shifts of the outer levels caused by a K shell spectator vacancy. Comparison with ab initio relativistic multiconfigurational Dirac-Fock calculations reveals that while the influence of relativity and QED effects is mostly accounted for, discrepancies remain in the lines' intensity ratio, which sensitively measures the intermediacy of the coupling. Similar discrepancies, of unknown origin, are found in the energy shifts of the outer levels due to the final-state K shell spectator vacancy.

  20. 如何在碳交易市场下对工业部门进行碳排放权分配--加州碳排放权交易市场的经验%Direct Allocation of Emission Allowances for Industrial Sectors--Experience from California's Cap-and-Trade Program

    Institute of Scientific and Technical Information of China (English)

    鲁虹佑; 周勇

    2013-01-01

    美国加州于2012年正式启动碳排放权交易市场,其排放权主要通过拍卖和免费分配两种方式发放。本文重点介绍美国加州碳排放权交易项目如何对工业企业进行排放权的分配,包括实现排放权分配的先决条件,包括法律支持,严格的数据上报和总排放配额的设定;如何防止温室气体排放的“泄漏”,保护加州工业企业的竞争力;以及如何制定标杆对企业进行排放权分配。%Under a Cap-and-Trade market, industrial sectors often obtain allowances of greenhouse gas emissions through auction or allocation. Allowances are given to the highest bidders when they are auctioned. Freely allocated or grandfathered allowances are given to industrial companies based on a pre-determined amount based on specific conditions of the indus-trial company. California launched its Cap-and-Trade program in 2012. Allowances for industrial sectors in California can be obtained through both auction and allocation. This report focuses on how allowances are freely allocated to industrial companies, including prerequisites for allowances allocation, prevention of emission leakage, maintain of industrial sec-tor’s competitiveness, and methodologies for developing emission benchmarks for allocation.

  1. Equilibrium magnetic states in individual hemispherical permalloy caps

    Energy Technology Data Exchange (ETDEWEB)

    Streubel, Robert; Schmidt, Oliver G. [Institute for Integrative Nanosciences, IFW Dresden, 01069 Dresden (Germany); Material Systems for Nanoelectronics, Chemnitz University of Technology, 09107 Chemnitz (Germany); Kravchuk, Volodymyr P.; Gaididei, Yuri [Bogolyubov Institute for Theoretical Physics, 03143 Kiev (Ukraine); Sheka, Denis D. [Radiophysics Faculty, Taras Shevchenko National University of Kiev, 01601 Kiev (Ukraine); Makarov, Denys [Institute for Integrative Nanosciences, IFW Dresden, 01069 Dresden (Germany); Kronast, Florian [Helmholtz-Zentrum Berlin fuer Materialien und Energie GmbH, 12489 Berlin (Germany)

    2012-09-24

    The magnetization distributions in individual soft magnetic permalloy caps on non-magnetic spherical particles with sizes ranging from 50 to 800 nm are investigated. We experimentally visualize the magnetic structures at the resolution limit of the x-ray magnetic circular dichroism photoelectron emission microscopy (XMCD-PEEM). By analyzing the so-called tail contrast in XMCD-PEEM, the spatial resolution is significantly enhanced, which allowed us to explore magnetic vortices and their displacement on curved surfaces. Furthermore, cap nanostructures are modeled as extruded hemispheres to determine theoretically the phase diagram of equilibrium magnetic states. The calculated phase diagram agrees well with the experimental observations.

  2. Pre-equilibrium emission in neutron induced reactions on /sup 54,56/Fe

    Energy Technology Data Exchange (ETDEWEB)

    Avrigeanu, M.; Ivascu, M.; Avrigeanu, V.

    1988-02-01

    The experimentally well known (n,p), (n,..cap alpha..) and (n,2n) reaction excitation functions, from threshold to 20 MeV incident energy, and neutron and proton emission spectra at 14.8 MeV from /sup 54,56/Fe targets are calculated in the frame of the geometry-dependent hybrid pre-equilibrium emission model, including angular momentum and parity conservation, and the Hauser-Feshbach statistical model. Use of a consistent statistical model parameter set enables the validation of the pre-equilibrium emission model. Moreover, an enhanced pre-equilibrium emission from higher spin composite system states, associated with higher incoming orbital momenta, has been evidenced. Higher orbital momenta involved also in the emergent channels of the process are suggested by calculations of the residual nuclei level populations.

  3. ATLAS - End-Cap calorimeter

    CERN Multimedia

    2006-01-01

    The End-cap calorimeter was moved with the help of the rails and this calorimeter will measure the energy of particles close to the beam axis when protons collide. Cooling is important for maximum detector efficiency.

  4. The Lyman alpha reference sample

    DEFF Research Database (Denmark)

    Hayes, M.; Östlin, G.; Schaerer, D.

    2013-01-01

    We report on new imaging observations of the Lyman alpha emission line (Lyα), performed with the Hubble Space Telescope, that comprise the backbone of the Lyman alpha Reference Sample. We present images of 14 starburst galaxies at redshifts 0.028 alpha emission line (Lyα), performed with the Hubble Space Telescope, that comprise the backbone of the Lyman alpha Reference Sample. We present images of 14 starburst galaxies at redshifts 0.028 ... with quantities that scale with dust content, in the sense that a low dust abundance is a necessary requirement (although not the only one) in order to spread Lyα photons throughout the interstellar medium and drive a large extended Lyα halo. © 2013. The American Astronomical Society. All rights reserved....

  5. Alpha fetoprotein

    Science.gov (United States)

    Fetal alpha globulin; AFP ... Greater than normal levels of AFP may be due to: Cancer in testes , ovaries, biliary (liver secretion) tract, stomach, or pancreas Cirrhosis of the liver Liver cancer ...

  6. K(alpha) x-ray emission characterization of 100 Hz, 15 mJ femtosecond laser system with high contrast ratio.

    Science.gov (United States)

    Fourmaux, S; Serbanescu, C; Kincaid, R E; Krol, A; Kieffer, J C

    2008-12-12

    We report K(alpha) x-ray production with a high energy (110 mJ per pulse at 800 nm before compression/15 mJ at 400 nm after compression), high repetition rate (100 Hz), and high pulse contrast (better than 10(-9) at 400 nm) laser system. To develop laser-based x-ray sources for biomedical imaging requires to use high-energy and high-power ultra-fast laser system where compression is achieved under vacuum. Using this type of laser system, we demonstrate long-term stability of the x-ray yield, conversion efficiency higher than 1.5 x 10(-5) with a Mo target, and the x-ray spot size close to the optical focal spot. This high-repetition K(alpha) x-ray source can be very useful for x-ray phase-contrast imaging.

  7. Comparison of human CAP and CAP2, homologs of the yeast adenylyl cyclase-associated proteins.

    Science.gov (United States)

    Yu, G; Swiston, J; Young, D

    1994-06-01

    We previously reported the identification of human CAP, a protein that is related to the Saccharomyces cerevisiae and Schizosaccharomyces pombe adenylyl cyclase-associated CAP proteins. The two yeast CAP proteins have similar functions: the N-terminal domains are required for the normal function of adenylyl cyclase, while loss of the C-terminal domains result in morphological and nutritional defects that are unrelated to the cAMP pathways. We have amplified and cloned cDNAs from a human glioblastoma library that encode a second CAP-related protein, CAP2. The human CAP and CAP2 proteins are 64% identical. Expression of either human CAP or CAP2 in S. cerevisiae cap- strains suppresses phenotypes associated with deletion of the C-terminal domain of CAP, but does not restore hyper-activation of adenylyl cyclase by RAS2val19. Similarly, expression of either human CAP or CAP2 in S. pombe cap- strains suppresses the morphological and temperature-sensitive phenotypes associated with deletion of the C-terminal domain of CAP in this yeast. In addition, expression of human CAP, but not CAP2, suppresses the propensity to sporulate due to deletion of the N-terminal domain of CAP in S. pombe. This latter observation suggests that human CAP restores normal adenylyl cyclase activity in S. pombe cap- cells. Thus, functional properties of both N-terminal and C-terminal domains are conserved between the human and S. pombe CAP proteins.

  8. Define a course for the France in the european system of emissions quotas exchange in agreement with the European Emission Trading Scheme directive; Definir un cap pour la France dans le systeme europeen d'echange de quotas d'emissions en accord avec la directive 'ETS'

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-04-15

    The project aims to define an independent evaluation of a course in France for the application of the European Emissions Trading Scheme, in the part I and II, taking into account the objective of the emission trading directive, using public data available in march 2006. In a first part the author presents the five key criteria which should be used to define the National Allocation Plan. The next part is the definition of the course and the last part the implications of the course. (A.L.B.)

  9. Evaluating Renewable Portfolio Standards and Carbon Cap Scenarios in the U.S. Electric Sector

    Energy Technology Data Exchange (ETDEWEB)

    Bird, L.; Chapman, C.; Logan, J.; Sumner, J.; Short, W.

    2010-05-01

    This report examines the impact of various renewable portfolio standards (RPS) and cap-and-trade policy options on the U.S. electricity sector, focusing mainly on renewable energy generation. The analysis uses the National Renewable Energy Laboratory's Regional Energy Deployment System (ReEDS) model that simulates the least-cost expansion of electricity generation capacity and transmission in the United States to examine the impact of an emissions cap--similar to that proposed in the Waxman-Markey bill (H.R. 2454)--as well as lower and higher cap scenarios. It also examines the effects of combining various RPS targets with the emissions caps. The generation mix, carbon emissions, and electricity price are examined for various policy combinations to simulate the effect of implementing policies simultaneously.

  10. Dynamic Interaction between Cap & Trade and Electricity Markets

    Science.gov (United States)

    Jeev, Kumar

    Greenhouse Gases (GHG), such as Carbon-Dioxide (CO2), which is released in the atmosphere due to anthropogenic activities like power production, are now accepted as the main culprits for global warming. The Regional Greenhouse Gas Initiative (RGGI), an initiative of the North East and Mid-Atlantic States of the United States (US) for limiting the emission of GHG, has developed a regional cap-and-trade program for CO2 emissions for power plants. Existing cap-and-trade programs in US and Europe for Greenhouse Gases have recently been plagued by over-allocation. Carbon prices recently collapsed in all these markets during the global recession. Since then, there have been significant policy changes, which have resulted in the adoption of aggressive emission cap targets by most major carbon emission markets. This is expected to make carbon emissions availability more restrictive, raising the prices of these credits. These emissions markets are expected to have a major impact on the wholesale electricity markets. Two models to study the interaction of these two markets are presented. These models assess the impact of the emissions market on wholesale electricity prices. The first model characterizes the competition between two types of power plants (coal and gas) in both the electricity and emissions markets as a dynamic game using the Cournot approximation. Under this approximation, we find that in the Nash equilibrium the plants increase their permit allocation to high-demand periods and the marginal value of each credit for a plant is identical in all periods under their optimal equilibrium strategy. The second numerical model allows us to explicitly evaluate the closed loop equilibrium of the dynamic interaction of two competitors in these markets. We find that plants often try to corner the market and push prices all the way to the price cap. Power plants derive most of their profits from these extreme price regimes. In the experiments where trading is allowed

  11. Correlation between defects in capped ZnO nanoparticles and their antibacterial activity.

    Science.gov (United States)

    Dutta, Raj Kumar; Nenavathu, Bhavani P; Gangishetty, Mahesh K

    2013-09-05

    Antibacterial activity of ZnO nanoparticles (NPs) triggered by generation of reactive oxygen species (ROS) depends on the fate of photoexcited charge carriers. Batches of wide band gap ZnO NPs of 7-9nm sizes, capped with polyethylene glycol (PEG), ascorbic acid (AsA), mercaptoacetic acid (MAA) and polysorbate 80 (T-80) were synthesized by precipitation method. These capped ZnO NPs exhibited ROS induced antibacterial activity, where the ROS was measured by TBARS assay. The PEG capped and AsA capped ZnO NPs exhibited weaker antibacterial activity and were correlated with strong and broad green emission peak owing to oxygen vacancies. The oxygen vacancies were trap sites of photoexcited electrons which inhibited interaction between the photoexcited electrons and oxygen on the surface of the ZnO NPs and accounted for lesser ROS generation and subsequently weaker antibacterial activity. Contrastingly MAA capped and T-80 capped ZnO NPs did not exhibit significant green emission peak, but exhibited 13% and 43% inhibition of growth of E. coli, respectively. The lack of oxygen vacancy defects in MAA capped and T-80 capped ZnO NPs perhaps led to lesser trapping of charge carriers, which is favorable for higher ROS generation and consequently higher antibacterial activity.

  12. Magnetically capped rolled-up nanomembranes.

    Science.gov (United States)

    Streubel, Robert; Thurmer, Dominic J; Makarov, Denys; Kronast, Florian; Kosub, Tobias; Kravchuk, Volodymyr; Sheka, Denis D; Gaididei, Yuri; Schäfer, Rudolf; Schmidt, Oliver G

    2012-08-01

    Modifying the curvature in magnetic nanostructures is a novel and elegant way toward tailoring physical phenomena at the nanoscale, allowing one to overcome limitations apparent in planar counterparts. Here, we address curvature-driven changes of static magnetic properties in cylindrically curved magnetic segments with different radii of curvature. The curved architectures are prepared by capping nonmagnetic micrometer- and nanometer-sized rolled-up membranes with a soft-magnetic 20 nm thick permalloy (Ni(80)Fe(20)) film. A quantitative comparison between the magnetization reversal processes in caps with different diameters is given. The phase diagrams of magnetic equilibrium domain patterns (diameter versus length) are generated. For this, joint experimental, including X-ray magnetic circular dichroism photoelectron emission microscopy (XMCD-PEEM), and theoretical studies are carried out. The anisotropic magnetostatic interaction in cylindrically curved architectures originating from the thickness gradient reduces substantially the magnetostatic interaction between closely packed curved nanowires. This feature is beneficial for racetrack memory devices, since a much higher areal density might be achieved than possible with planar counterparts.

  13. The North Zealand CAP Monitor

    DEFF Research Database (Denmark)

    Nielsen, Minna; Ravn, Pernille; Notander Clausen, Lise

    Contect We describe how we developed a monitoring system for community acquired pneumonia (CAP) at North Zealand Regional hospital. We serve 310.000 inhabitants and annually around 3200 patients with CAP are admitted. As part of a program of clinical pathways for common conditions, a pathway...... for pneumonia was designed and implemented in 2010. Problem In spite of our clinical pathway for CAP we found delays in start of treatment, overuse of antibiotics and long length of stay (LOS). Mortality was nearly 20 %. Assessment of problem and analysis of its causes We established an audit group of two...... nurses and two senior doctors. Direct observations of the clinical processes revealed problems of coordination, complex disease trajectories that did not fit with the pneumonia pathway, unclear guidelines and variation in their interpretation. Intervention We designed a measurement system to monitor...

  14. Alpha particle emitters in medicine

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, D.R.

    1989-09-01

    Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical applications of alpha emitters. In recent years, however, the potential use of antibodies labeled with alpha emitting radionuclides against cancer has seemed promising because alpha particles are highly effective in cell killing. High dose rates at high LET, effectiveness under hypoxic conditions, and minimal expectancy of repair are additional advantages of alpha emitters over antibodies labeled with beta emitting radionuclides for cancer therapy. Cyclotron-produced astatine-211 ({sup 211}At) and natural bismuth-212 ({sup 212}Bi) have been proposed and are under extensive study in the United States and Europe. Radium-223 ({sup 223}Ra) also has favorable properties as a potential alpha emitting label, including a short-lived daughter chain with four alpha emissions. The radiation dosimetry of internal alpha emitters is complex due to nonuniformly distributed sources, short particle tracks, and high relative specific ionization. The variations in dose at the cellular level may be extreme. Alpha-particle radiation dosimetry, therefore, must involve analysis of statistical energy deposition probabilities for cellular level targets. It must also account fully for nonuniform distributions of sources in tissues, source-target geometries, and particle-track physics. 18 refs., 4 figs.

  15. The Seyfert 2 galaxy NGC 2110: hard X-ray emission observed by NuSTAR and variability of the iron K$\\alpha$ line

    CERN Document Server

    Marinucci, A; Bianchi, S; Lu, T N; Arevalo, P; Baloković, M; Ballantyne, D; Bauer, F E; Boggs, S E; Christensen, F E; Craig, W W; Gandhi, P; Hailey, C J; Harrison, F; Puccetti, S; Rivers, E; Walton, D J; Stern, D; Zhang, W

    2014-01-01

    We present NuSTAR observations of the bright Seyfert 2 galaxy NGC 2110 obtained in 2012, when the source was at the highest flux level ever observed, and in 2013, when the source was at a more typical flux level. We include archival observations from other X-ray satellites, namely XMM-Newton, Suzaku, BeppoSAX, Chandra and Swift. Simultaneous NuSTAR and Swift broad band spectra (in the 3-80 keV range) indicate a cutoff energy $E_{\\rm c}>210$ keV, with no detectable contribution from Compton reflection. NGC 2110 is one of the very few sources where no evidence for distant Compton thick scattering is found and, by using temporal information collected over more than a decade, we investigate variations of the iron K$\\alpha$ line on time scales of years. The Fe K$\\alpha$ line is likely the sum of two components: one constant (originating from distant Compton-thick material) and the other one variable and linearly correlated with the source flux (possibly arising from Compton-thin material much closer to the black h...

  16. Comment on "The dust sublimation radius as an outer envelope to the bulk of the narrow Fe K$\\alpha$ line emission in Type 1 AGN"

    CERN Document Server

    Minezaki, Takeo

    2015-01-01

    Recently, Gandhi, H\\"onig, and Kishimoto submitted a manuscript to the arXiv e-print service on the location of the emitting region of the narrow FeK$\\alpha $ line that appears in the X-ray spectra of active galactic nuclei (AGNs) compared with the inner radius of the dust torus (arXiv:1502.02661). Prior to their manuscript, a similar discussion had already been presented in a section of Minezaki & Matsushita (2015), which had been accepted for publication in the Astrophysical Journal. Because Gandhi et al. made no reference to Minezaki & Matsushita (2015) apart from improperly citing it merely as an application of the dust reverberation of AGNs, we present a brief comparison of both papers. Gandhi et al. compared the location of the FeK$\\alpha$ emitting region with the individually measured radius of the dust torus for type 1 AGNs, whereas Minezaki & Matsushita (2015) examined it based on the scaling relation of the dust reverberation radius for both type 1 and type 2 AGNs. Nevertheless, Gandhi e...

  17. The Seyfert 2 Galaxy NGC 2110: Hard X-Ray Emission Observed by NuStar and Variability of the Iron K-Alpha Line

    Science.gov (United States)

    Marinucci, A.; Matt, G.; Bianchi, S.; Lu, T. N.; Arevalo, P.; Balokovic, M.; Ballantyne, D.; Bauer, F. E.; Boggs, S. E.; Stern, D.; Zhang, William W.

    2014-01-01

    We present NuSTAR observations of the bright Seyfert 2 galaxy NGC 2110 obtained in 2012, when the source was at the highest flux level ever observed, and in 2013, when the source was at a more typical flux level. We include archival observations from other X-ray satellites, namely XMM-Newton, Suzaku, BeppoSAX, Chandra and Swift. Simultaneous NuSTAR and Swift broad band spectra (in the 3-80 keV range) indicate a cutoff energy E(sub c) greater than 210 keV, with no detectable contribution from Compton reflection. NGC 2110 is one of the very few sources where no evidence for distant Compton thick scattering is found and, by using temporal information collected over more than a decade, we investigate variations of the iron K(alpha) line on time scales of years. The Fe K alpha line is likely the sum of two components: one constant (originating from distant Compton-thick material) and the other one variable and linearly correlated with the source flux (possibly arising from Compton-thin material much closer to the black hole).

  18. Complex Variability of the H$\\alpha$ Emission Line Profile of the T Tauri Binary System KH 15D: The Influence of Orbital Phase, Occultation by the Circumbinary Disk, and Accretion Phenomenae

    CERN Document Server

    Hamilton, Catrina M; Mundt, Reinhard; Herbst, William; Winn, Joshua N

    2012-01-01

    We have obtained 48 high resolution echelle spectra of the pre-main sequence eclipsing binary system KH~15D (V582 Mon, P = 48.37 d, $e$ $\\sim$ 0.6, M$_{A}$ = 0.6 M$_{\\odot}$, M$_{B}$ = 0.7 M$_{\\odot}$). The eclipses are caused by a circumbinary disk seen nearly edge on, which at the epoch of these observations completely obscured the orbit of star B and a large portion of the orbit of star A. The spectra were obtained over five contiguous observing seasons from 2001/2002 to 2005/2006 while star A was fully visible, fully occulted, and during several ingress and egress events. The H$\\alpha$ line profile shows dramatic changes in these time series data over timescales ranging from days to years. A fraction of the variations are due to "edge effects" and depend only on the height of star A above or below the razor sharp edge of the occulting disk. Other observed variations depend on the orbital phase: the H$\\alpha$ emission line profile changes from an inverse P Cygni type profile during ingress to an enhanced d...

  19. Effects of chain length and Au spin-orbit coupling on 3(pi pi*) emission from bridging Cn2- units: theoretical characterization of spin-forbidden radiative transitions in metal-capped one-dimensional carbon chains [H3PAu(C[triple bond]C)nAuPH3].

    Science.gov (United States)

    Cao, Zexing; Zhang, Qianer

    2004-04-19

    Density functional theory and CASSCF calculations have been used to optimize the geometries of binuclear gold(I) complexes [H(3)PAu(C[triple bond]C)(n)AuPH(3)] (n=1-6) in their ground states and selected lowest energy (3)(pi pi*) excited states. Vertical excitation energies obtained by time-dependent density functional calculations for the spin-forbidden singlet-triplet transitions have exponential-decay size dependence. The predicted singlet-triplet splitting limit of [H(3)PAu(C[triple bond]C)(proportional/variant)AuPH(3)] is about 8317 cm(-1). Calculated singlet-triplet transition energies are in reasonable agreement with available experimental observations. The effect of the heavy atom Au spin-orbit coupling on the (3)(pi pi*) emission of these metal-capped one-dimensional carbon allotropes has been investigated by MRCI calculations. The contribution of the spin- and dipole-allowed singlet excited state to the spin-orbit-coupling wave function of the (3)(pi pi*) excited state makes the low-lying acetylenic triplet excited states become sufficiently allowed so as to appear in both electronic absorption and emission.

  20. $\\alpha_s$ review (2016)

    CERN Document Server

    d'Enterria, David

    2016-01-01

    The current world-average of the strong coupling at the Z pole mass, $\\alpha_s(m^2_{Z}) = 0.1181 \\pm 0.0013$, is obtained from a comparison of perturbative QCD calculations computed, at least, at next-to-next-to-leading-order accuracy, to a set of 6 groups of experimental observables: (i) lattice QCD "data", (ii) $\\tau$ hadronic decays, (iii) proton structure functions, (iv) event shapes and jet rates in $e^+e^-$ collisions, (v) Z boson hadronic decays, and (vi) top-quark cross sections in p-p collisions. In addition, at least 8 other $\\alpha_s$ extractions, usually with a lower level of theoretical and/or experimental precision today, have been proposed: pion, $\\Upsilon$, W hadronic decays; soft and hard fragmentation functions; jets cross sections in pp, e-p and $\\gamma$-p collisions; and photon F$_2$ structure function in $\\gamma\\,\\gamma$ collisions. These 14 $\\alpha_s$ determinations are reviewed, and the perspectives of reduction of their present uncertainties are discussed.

  1. Evaluating renewable portfolio standards and carbon cap scenarios in the U.S. electric sector

    Energy Technology Data Exchange (ETDEWEB)

    Bird, Lori; Chapman, Caroline; Logan, Jeff [National Renewable Energy Laboratory (NREL), 1617 Cole Boulevard, MS RSF 100, Golden, CO 80401 (United States); Sumner, Jenny, E-mail: jenny.sumner@nrel.go [National Renewable Energy Laboratory (NREL), 1617 Cole Boulevard, MS RSF 100, Golden, CO 80401 (United States); Short, Walter [National Renewable Energy Laboratory (NREL), 1617 Cole Boulevard, MS RSF 100, Golden, CO 80401 (United States)

    2011-05-15

    This report examines the impact of renewable portfolio standards (RPS) and cap-and-trade policy options on the U.S. electricity sector. The analysis uses the National Renewable Energy Laboratory's Regional Energy Deployment System (ReEDS) model that simulates the least-cost expansion of electricity generation capacity and transmission in the U.S. to examine the impact of a variety of emissions caps-and RPS scenarios both individually and combined. The generation mix, carbon emissions, and electricity price are examined for various policy combinations simulated in the modeling. - Research highlights: {yields} The report examines renewable portfolio standards and cap-and-trade policy options. {yields} The analysis uses the NREL's Regional Energy Deployment System model. {yields} A carbon emissions cap and an RPS can be complementary policies.{yields} The cap alone case drives significant renewable generation.{yields} A 25% RPS has similar near term emissions as base cap at similar electricity price.

  2. Pulsar Polar Cap and Slot Gap Models: Confronting Fermi Data

    Science.gov (United States)

    Harding, Alice K.

    2012-01-01

    Rotation-powered pulsars are excellent laboratories for studying particle acceleration as well as fundamental physics of strong gravity, strong magnetic fields and relativity. I will review acceleration and gamma-ray emission from the pulsar polar cap and slot gap. Predictions of these models can be tested with the data set on pulsars collected by the Large Area Telescope on the Fermi Gamma-Ray Telescope over the last four years, using both detailed light curve fitting and population synthesis.

  3. Parametric study of propeller boss cap fins for container ships

    Directory of Open Access Journals (Sweden)

    Lim Sang-Seop

    2014-06-01

    Full Text Available The global price of oil, which is both finite and limited in quantity, has been rising steadily because of the increasing requirements for energy in both developing and developed countries. Furthermore, regulations have been strengthened across all industries to address global warming. Many studies of hull resistance, propulsion and operation of ships have been performed to reduce fuel consumption and emissions. This study examined the design parameters of the propeller boss cap fin (PBCF and hub cap for 6,000TEU container ships to improve the propulsion efficiency. The design parameters of PBCF have been selected based on the geometrical shape. Computational fluid dynamics (CFD analysis with a propeller open water (POW test was performed to check the validity of CFD analysis. The design of experiment (DOE case was selected as a full factorial design, and the experiment was analyzed by POW and CFD analysis. Analysis of variance (ANOVA was performed to determine the correlation among design parameters. Four design alternatives of PBCF were selected from the DOE. The shape of a propeller hub cap was selected as a divergent shape, and the divergent angle was determined by the DOE. Four design alternatives of PBCF were attached to the divergent hub cap, and the POW was estimated by CFD. As a result, the divergent hub cap with PBCF has a negative effect on the POW, which is induced by an increase in torque coefficient. A POW test and cavitation test were performed with a divergent hub cap with PBCF to verify the CFD result. The POW test result showed that the open water efficiency was increased approximately 2% with a divergent hub cap compared to a normal cap. The POW test result was similar to the CFD result, and the divergent hub cap with the PBCF models showed lower open water efficiency. This was attributed to an increase in the torque coefficient just like the CFD results. A cavitation test was performed using the 2 models selected. The test

  4. Making carbon nanotube electron sources of defined lengths and with closed caps.

    Science.gov (United States)

    Heeres, Erwin C; Oosterkamp, Tjerk H; de Jonge, Niels

    2011-06-10

    A method is reported to make an electron source consisting of an individual multi-walled carbon nanotube (MWNT) mounted on a tungsten support tip, and cut to length using localized electron beam irradiation in a scanning electron microscope. The apex of the MWNT was transformed into a closed cap with at least one fullerene-like layer via an annealing process involving simultaneous heating and the extraction of an emission current of ∼ 1 mA. The electron emission occurred at localized emission sites. The electron emission showed Fowler-Nordheim behavior, was highly stable with time, and exhibited a low energy spread. The structure of the caps of two MWNTs was studied with transmission electron microscopy before and after the cap closure.

  5. From Blogs to Bottle Caps

    Science.gov (United States)

    Edinger, Ted

    2012-01-01

    There is a wonderful community of art educators connecting a once-isolated profession through blogging. Art educators around the world are sharing ideas and communicating with their peers through this amazing resource. In this article, the author describes the bottle cap mural at Tulip Grove Elementary School which was inspired by this exchange of…

  6. What Powers Lyman alpha Blobs?

    CERN Document Server

    Ao, Y; Beelen, A; Henkel, C; Cen, R; De Breuck, C; Francis, P; Kovacs, A; Lagache, G; Lehnert, M; Mao, M; Menten, K M; Norris, R; Omont, A; Tatemastu, K; Weiss, A; Zheng, Z

    2015-01-01

    Lyman alpha blobs (LABs) are spatially extended lyman alpha nebulae seen at high redshift. The origin of Lyman alpha emission in the LABs is still unclear and under debate. To study their heating mechanism(s), we present Australia Telescope Compact Array (ATCA) observations of the 20 cm radio emission and Herschel PACS and SPIRE measurements of the far-infrared (FIR) emission towards the four LABs in the protocluster J2143-4423 at z=2.38. Among the four LABs, B6 and B7 are detected in the radio with fluxes of 67+/-17 microJy and 77+/-16 microJy, respectively, and B5 is marginally detected at 3 sigma (51+/-16 microJy). For all detected sources, their radio positions are consistent with the central positions of the LABs. B6 and B7 are obviously also detected in the FIR. By fitting the data with different templates, we obtained redshifts of 2.20$^{+0.30}_{-0.35}$ for B6 and 2.20$^{+0.45}_{-0.30}$ for B7 which are consistent with the redshift of the lyman alpha emission within uncertainties, indicating that both ...

  7. Is \\gamma-ray emission from novae affected by interference effects in the 18F(p,\\alpha)15O reaction?

    CERN Document Server

    Laird, A M; Murphy, A St J; Wimmer, K; Chen, A A; Deibel, C M; Faestermann, T; Fox, S P; Fulton, B R; Hertenberger, R; Irvine, D; José, J; Longland, R; Mountford, D; Sambrook, B; Seiler, D; Wirth, H -F

    2012-01-01

    The 18F(p,\\alpha)15O reaction rate is crucial for constraining model predictions of the \\gamma-ray observable radioisotope 18F produced in novae. The determination of this rate is challenging due to particular features of the level scheme of the compound nucleus, 19Ne, which result in interference effects potentially playing a significant role. The dominant uncertainty in this rate arises from interference between J\\pi=3/2+ states near the proton threshold (Sp = 6.411 MeV) and a broad J\\pi=3/2+ state at 665 keV above threshold. This unknown interference term results in up to a factor of 40 uncertainty in the astrophysical S-factor at nova temperatures. Here we report a new measurement of states in this energy region using the 19F(3He,t)19Ne reaction. In stark contrast with previous assumptions we find at least 3 resonances between the proton threshold and Ecm=50 keV, all with different angular distributions. None of these are consistent with J\\pi= 3/2+ angular distributions. We find that the main uncertainty ...

  8. Detection of Broad H$\\alpha$ Emission Lines in the Late-time Spectra of a Hydrogen-poor Superluminous Supernova

    CERN Document Server

    Yan, Lin; Ofek, E; Gal-Yam, A; Mazzali, P; Perley, D; Vreeswijk, P; Leloudas, G; de Cia, A; Masci, F; Cenko, S B; Cao, Y; Kulkarni, S R; Nugent, P E; Rebbapragada, Umaa D; Woźniak, P R; Yaron, O

    2015-01-01

    iPTF13ehe is a hydrogen-poor superluminous supernova (SLSN) at z=0.3434, with properties similar to SN2007bi. It rises within (83-148)days (rest-frame) to reach a peak bolometric luminosity of 1.3x$10^{44}$erg/s, then decays very slowly at 0.015mag. per day. The measured ejecta velocity is 13000km/s. The inferred explosion characteristics, such as the ejecta mass (67-220$M_\\odot$), the total radiative and kinetic energy ($10^{51}$ & 2x$10^{53}$erg respectively), is typical of SLSN-R events. However, the late-time spectrum taken at +251days reveals a Balmer Halpha emission feature with broad and narrow components, which has never been detected before among other H-poor SLSNe. The broad component has a velocity width of ~4500km/s and has a ~300km/s blue-ward shift relative to the narrow component. We interpret this broad Halpha emission line as the interaction between the supernova ejecta and a H-rich circumstellar medium (CSM) shell, located at a distance of ~4x$10^{16}$cm from the explosion site. This eje...

  9. ATLAS End Cap toroid in upstanding position

    CERN Multimedia

    2005-01-01

    End Cap toroid The ATLAS End Cap toroid weights 240-ton and is 12-m diameter high. The parts of this vacuum vessel had to be integrated and tested so that End Cap Toroid has no leaks. After that it could be cooled down to 80 K.

  10. Analyses of hydraulic performance of velocity caps

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Degn Eskesen, Mark Chr.; Buhrkall, Jeppe;

    2014-01-01

    The hydraulic performance of a velocity cap has been investigated. Velocity caps are often used in connection with offshore intakes. CFD (computational fluid dynamics) examined the flow through the cap openings and further down into the intake pipes. This was combined with dimension analyses...

  11. Motion of polar cap arcs

    Science.gov (United States)

    Hosokawa, K.; Moen, J. I.; Shiokawa, K.; Otsuka, Y.

    2011-01-01

    A statistics of motion of polar cap arcs is conducted by using 5 years of optical data from an all-sky imager at Resolute Bay, Canada (74.73°N, 265.07°E). We identified 743 arcs by using an automated arc detection algorithm and statistically examined their moving velocities as estimated by the method of Hosokawa et al. (2006). The number of the arcs studied is about 5 times larger than that in the previous statistics of polar cap arcs by Valladares et al. (1994); thus, we could expect to obtain more statistically significant results. Polar cap arcs are found to fall into two distinct categories: the By-dependent and By-independent arcs. The motion of the former arcs follows the rule reported by Valladares et al. (1994), who showed that stable polar cap arcs move in the direction of the interplanetary magnetic field (IMF) By. About two thirds of the arcs during northward IMF conditions belong to this category. The latter arcs always move poleward irrespective of the sign of the IMF By, which possibly correspond to the poleward moving arcs in the morning side reported by Shiokawa et al. (1997). At least one third of the arcs belong to this category. The By-dependent arcs tend to move faster when the magnitude of the IMF By is larger, suggesting that the transport of open flux by lobe reconnection from one polar cap compartment to the other controls their motion. In contrast, the speed of the By-independent arcs does not correlate with the magnitude of the By. The motions of both the By-dependent and By-independent arcs are most probably caused by the magnetospheric convection. Convection in the region of By-dependent arcs is affected by the IMF By, which indicates that their sources may be on open field lines or in the closed magnetosphere adjacent to the open-closed boundary, whereas By-independent arcs seem to be well on closed field lines. Hence, the magnetospheric source of the two types of arc may be different. This implies that the mechanisms causing the

  12. From symmetric cold fission fragment mass distributions to extremely asymmetric alpha decay

    Energy Technology Data Exchange (ETDEWEB)

    Poenaru, D.N.; Ivascu, M.; Maruhn, J.A.; Greiner, W.

    1987-12-10

    The analytical superasymmetric fission model, successful in the study of extremely asymmetric decay modes like ..cap alpha..-decay and heavy ion radioactivities, is applied to cold fission phenomena. The three groups of processes are described in a unifield manner, showing that cold fission could be considered heavy cluster emission. For /sup 234/U all groups have been detected. The highest symmetry of the gragment mass distributions should be observed for the neutron rich nucleus /sup 264/Fm, leading to doubly magic products /sup 132/Sn. The most probable light fragments from cold fission of /sup 234,236/U, /sup 239/Np and /sup 240/Pu are /sup 100/Zr, /sup 104,106,108/Mo respectively, in good agreement with experimental data.

  13. The dopaminergic system in patients with functional dyspepsia analysed by single photon emission computed tomography (SPECT) and an alpha-methyl-para-tyrosine (AMPT) challenge test

    Energy Technology Data Exchange (ETDEWEB)

    Braak, Breg; Klooker, Tamira K. [Academic Medical Center, Department of Gastroenterology and Hepatology, Amsterdam (Netherlands); Booij, Jan [Academic Medical Center, Department of Nuclear Medicine, Amsterdam (Netherlands); Wijngaard, Rene M.J. van den [Academic Medical Center, Tytgat Institute of Liver and Intestinal Research, Amsterdam (Netherlands); Boeckxstaens, Guy E.E. [Academic Medical Center, Department of Gastroenterology and Hepatology, Amsterdam (Netherlands); University Hospital Leuven, Catholic University Leuven, Department of Gastroenterology, Leuven (Belgium)

    2012-04-15

    Functional dyspepsia (FD) is a chronic condition characterized by upper abdominal symptoms without an identifiable cause. While the serotonergic system is thought to play a key role in the regulation of gut physiology, the role of the dopaminergic system, which is important in the regulation of visceral pain and stress, is under-studied. Therefore, this study investigated the dopaminergic system and its relationship with drinking capacity and symptoms in FD patients. In FD patients and healthy volunteers (HV) the dopaminergic system was investigated by in-vivo assessment of central dopamine D2 receptors (D2Rs) with [{sup 123}I]IBZM SPECT and by an acute, but reversible, dopamine depletion alpha-methyl-para-tyrosine (AMPT) challenge test. A nutrient drink test was performed to investigate the association between maximal ingested volume, evoked symptoms, and D2Rs. The HV subjects comprised 12 women and 8 men (mean age 31 {+-} 3 years), and the FD patients comprised 5 women and 3 men (mean age 39 {+-} 5 years). The FD patients had a lower left plus right average striatal binding potential (BP{sub NP}) for the caudate nucleus (p = 0.02), but not for putamen (p = 0.15), which in the FD patients was correlated with maximal ingested volume (r = 0.756, p = 0.03). The D2R BP{sub NP} in the putamen was correlated with nausea (r = 0.857, p = 0.01). The acute dopamine depletion test, however, failed to reveal differences in prolactin release between the FD patients and the HV subjects. These preliminary data suggest that chronic rather than acute alterations in the dopaminergic system may be involved in the pathogenesis of FD. Further studies are required to reproduce our novel findings and to evaluate to what extent the dopaminergic changes may be secondary to abnormalities in serotonergic pathways. (orig.)

  14. NMR structural characterization of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum

    Energy Technology Data Exchange (ETDEWEB)

    Mavoungou, Chrystelle [Max Planck Institute for Biochemistry (Germany); Israel, Lars [Ludwig Maximilians-University, Adolf Butenandt Institute, Cell Biology (Germany); Rehm, Till; Ksiazek, Dorota; Krajewski, Marcin; Popowicz, Grzegorz [Max Planck Institute for Biochemistry (Germany); Noegel, Angelika A. [University of Cologne, Institute for Biochemistry (Germany); Schleicher, Michael [Ludwig Maximilians-University, Adolf Butenandt Institute, Cell Biology (Germany); Holak, Tad A. [Max Planck Institute for Biochemistry (Germany)

    2004-05-15

    Cyclase-associated proteins (CAPs) are highly conserved, ubiquitous actin binding proteins that are involved in microfilament reorganization. The N-termini of CAPs play a role in Ras signaling and bind adenylyl cyclase; the C-termini bind to G-actin. We report here the NMR characterization of the amino-terminal domain of CAP from Dictyostelium discoideum (CAP(1-226)). NMR data, including the steady state {sup 1}H-{sup 15}N heteronuclear NOE experiments, indicate that the first 50 N-terminal residues are unstructured and that this highly flexible serine-rich fragment is followed by a stable, folded core starting at Ser 51. The NMR structure of the folded core is an {alpha}-helix bundle composed of six antiparallel helices, in a stark contrast to the recently determined CAP C-terminal domain structure, which is solely built by {beta}-strands.

  15. NMR structural characterization of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum.

    Science.gov (United States)

    Mavoungou, Chrystelle; Israel, Lars; Rehm, Till; Ksiazek, Dorota; Krajewski, Marcin; Popowicz, Grzegorz; Noegel, Angelika A; Schleicher, Michael; Holak, Tad A

    2004-05-01

    Cyclase-associated proteins (CAPs) are highly conserved, ubiquitous actin binding proteins that are involved in microfilament reorganization. The N-termini of CAPs play a role in Ras signaling and bind adenylyl cyclase; the C-termini bind to G-actin. We report here the NMR characterization of the amino-terminal domain of CAP from Dictyostelium discoideum (CAP(1-226)). NMR data, including the steady state (1)H-(15)N heteronuclear NOE experiments, indicate that the first 50 N-terminal residues are unstructured and that this highly flexible serine-rich fragment is followed by a stable, folded core starting at Ser 51. The NMR structure of the folded core is an alpha-helix bundle composed of six antiparallel helices, in a stark contrast to the recently determined CAP C-terminal domain structure, which is solely built by beta-strands.

  16. Estimation of the alpha decay half-lives

    Energy Technology Data Exchange (ETDEWEB)

    Poenaru, D.N.; Ivascu, M. (Institute for Physics and Nuclear Engineering, Bucharest (Romania))

    1983-07-01

    Improved up to date versions of the known ..cap alpha.. decay half-lives formulae are obtained by changing the additive parameters in order to have a vanishing mean value of the absolute errors. A new semiempirical relationship is derived on the grounds of the fission theory of alpha decay. It takes into consideration explicitly the dependence on the difference from magicity both of the neutron and proton numbers. Allowing us to obtain better agreement with experimental data.

  17. Benzonorbornadiene end caps for PMR resins

    Science.gov (United States)

    Panigot, Michael J.; Waters, John F.; Varde, Uday; Sutter, James K.; Sukenik, Chaim N.

    1992-01-01

    Several ortho-disubstituted benzonorbornadiene derivatives are described. These molecules contain acid, ester, or anhydride functionality permitting their use as end caps in PMR (polymerization of monomer reactants) polyimide systems. The replacement of the currently used norbornenyl end caps with benzonorbornadienyl end caps affords resins of increased aromatic content. It also allows evaluation of some mechanistic aspects of PMR cross-linking. Initial testing of N-phenylimide model compounds and of actual resin formulations using the benzonorbornadienyl end cap reveals that they undergo efficient thermal crosslinking to give oligomers with physical properties and thermal stability comparable to commercial norbornene-end-capped PMR systems.

  18. In vitro refolding of heterodimeric CapZ expressed in E. coli as inclusion body protein.

    Science.gov (United States)

    Remmert, K; Vullhorst, D; Hinssen, H

    2000-02-01

    CapZ is a heterodimeric Ca(2+)-independent actin binding protein which plays an important role in organizing the actin filament lattice of cross-striated muscle cells. It caps the barbed end of actin filaments and promotes nucleation of actin polymerization, thereby regulating actin filament length. Here we report the expression of the two muscle-specific isoforms alpha2 and beta1, from chicken in Escherichia coli as individual subunits using the pQE60 expression vector and the subsequent renaturation of the functional CapZ heterodimer from inclusion bodies. Optimal renaturation conditions were obtained both by simultaneous refolding of urea-solubilized subunits and by rapid dilution into a buffer containing 20% glycerol, 5 mM EGTA, 2 mM DTT, 1 mM PMSF, and 100 mM Tris, pH 7.4. The refolding mixture was incubated for 24 h at 15 degrees C and the protein was concentrated by ultrafiltration. Biochemical characterization of the recombinant heterodimer revealed actin binding activities indistinguishable from those of native CapZ as purified from chicken skeletal muscle. Using the same protocol, we were able to refold the beta1, but not the alpha2 isoform as a single polypeptide, indicating a role for beta1 as a molecular template for the folding of alpha2. The reported recombinant approach leads to high yields of active heterodimer and allows the renaturation and characterization of the beta subunit.

  19. Synthesis, Structural and Optical Properties of TOPO and HDA Capped Cadmium Sulphide Nanocrystals, and the Effect of Capping Ligand Concentration

    Directory of Open Access Journals (Sweden)

    Damian C. Onwudiwe

    2015-01-01

    Full Text Available The thermal decomposition of bis(N,N-diallyldithiocarbamatoCd(II in a “one-pot” synthesis in tri-n-octylphosphine oxide (TOPO and hexadecylamine (HDA afforded CdS (TOPO-CdS and HDA-CdS of varying optical properties and morphologies. The influence of the ratio of the precursor concentration to the capping molecule, as a factor affecting the morphology and size of the nanoparticles, was investigated. The particles varied in shape from spheres to rods and show quantum size effects in their optical spectra with clear differences in the photoluminescence (PL spectra. The PL spectrum of the HDA capped CdS nanoparticles has an emission maximum centred at 468, 472, and 484 nm for the precursor to HDA concentration ratio of 1 : 10, 1 : 15, and 1 : 20, respectively, while the TOPO capped nanoparticles show emission peaks at 483, 494, and 498 nm at the same concentration ratio. Powdered X-ray diffraction (p-XRD shows the nanoparticles to be hexagonal. The crystallinity of the nanoparticles was evident from high resolution transmission electron microscopy (HRTEM which gave well-defined images of particles with clear lattice fringes.

  20. Influence of polar cap currents on pulsar polarization

    CERN Document Server

    Kumar, D

    2012-01-01

    We have developed a model for the polarization of curvature radiation for pulsars by taking into account the polar cap induced perturbation on the nonrotating (slowly rotating) dipolar magnetic field, where the rotation effects such as aberration and retardation can be ignored. We have simulated a set of typical pulse profiles to understand the role of induced magnetic field on radio emission of pulsars, and found to be significantly influencing the profile structure and polarization. Our model indicates that the intensity components and the polarization angle inflection point can get shifted to either leading or trailing side depending upon the prevailing conditions in the viewing geometry, the non-uniformity in source distribution (modulation) and the polar cap current induced perturbation. Also, we find an evidence for the origin of symmetric type circular polarization in addition to antisymmetric type. Our model predicts for a stronger trailing component compared to that on leading side of a given cone.

  1. X-rays from Alpha Centauri

    Science.gov (United States)

    Nugent, J.; Garmire, G.

    1978-01-01

    HEAO 1 observations of soft X-ray emission from a point source in the vicinity of Alpha Cen are reported. The source, designated H1437-61, is tentatively identified with Alpha Cen, and an X-ray luminosity comparable to that of the sun in an active state is estimated. A temperature of about 500,000 K and an emission integral of 5 x 10 to the 50th per cu cm are obtained. Coronal emission is suggested as the X-ray-producing mechanism.

  2. Green Pea Galaxies Reveal Secrets of Ly$\\alpha$ Escape

    CERN Document Server

    Yang, Huan; Gronke, Max; Rhoads, James E; Jaskot, Anne; Zheng, Zhenya; Dijkstra, Mark

    2015-01-01

    Star-formation in galaxies generates a lot of Ly$\\alpha$ photons. Understanding the escape of Ly$\\alpha$ photons from galaxies is a key issue in studying high redshift galaxies and probing cosmic reionization with Ly$\\alpha$. To understand Ly$\\alpha$ escape, it is valuable to study analogs of high redshift Ly$\\alpha$ emitters in nearby universe. However, most nearby analogs have too small a Ly$\\alpha$ equivalent width and escape fraction compared to high redshift Ly$\\alpha$ emitters. One different group of nearby analogs are "Green Pea" galaxies, selected by their high equivalent width optical emission lines. Here we show that Green Pea galaxies have strong Ly$\\alpha$ emission lines and high Ly$\\alpha$ escape fraction (see also Henry et al. 2015), providing an opportunity to solve Ly$\\alpha$ escape problem. Green Peas have a Ly$\\alpha$ equivalent width distribution similar to high redshift Ly$\\alpha$ emitters. The Ly$\\alpha$ escape fraction correlates with many quantities of Ly$\\alpha$ profile, especially the...

  3. New Commitment Options: Compatibility with Emissions Trading

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This paper considers different options for quantitative greenhouse gas emission commitments from the standpoint of their technical compatibility with emissions trading. These are dynamic targets, binding targets with price caps, non-binding targets, sector-wide targets/mechanisms, action targets, allowances and endowments, and long-term permits. This paper considers these options from the standpoint of their compatibility with emissions trading.

  4. Competitiveness and linking of emission trading systems

    Energy Technology Data Exchange (ETDEWEB)

    Hausotter, Tobias; Steuwer, Sibyl; Taenzler, Dennis [adelphi, Berlin (Germany)

    2011-01-15

    The establishment of emission trading systems raises concerns among industries regarding international competitive disadvantages for the industries under an emissions cap. This study aims to assess competitiveness exposure of industrial sectors and presents policy measures to address these concerns. Moreover, the study provides a comparison of different existing approaches to competitiveness concerns proposed by regional emission trading systems. (orig.)

  5. Anomalous Microwave Emission

    CERN Document Server

    Kogut, A J

    1999-01-01

    Improved knowledge of diffuse Galactic emission is important to maximize the scientific return from scheduled CMB anisotropy missions. Cross-correlation of microwave maps with maps of the far-IR dust continuum show a ubiquitous microwave emission component whose spatial distribution is traced by far-IR dust emission. The spectral index of this emission, beta_{radio} = -2.2 (+0.5 -0.7) is suggestive of free-free emission but does not preclude other candidates. Comparison of H-alpha and microwave results show that both data sets have positive correlations with the far-IR dust emission. Microwave data, however, are consistently brighter than can be explained solely from free-free emission traced by H-alpha. This ``anomalous'' microwave emission can be explained as electric dipole radiation from small spinning dust grains. The anomalous component at 53 GHz is 2.5 times as bright as the free-free emission traced by H-alpha, providing an approximate normalization for models with significant spinning dust emission.

  6. All-Sky Observational Evidence for An Inverse Correlation Between Dust Temperature and Emissivity Spectral Index

    Science.gov (United States)

    Liang, Z.; Fixsen, D. J.; Gold, B.

    2012-01-01

    We show that a one-component variable-emissivity-spectral-index model (the free- model) provides more physically motivated estimates of dust temperature at the Galactic polar caps than one- or two-component fixed-emissivity-spectral-index models (fixed- models) for interstellar dust thermal emission at far-infrared and millimeter wavelengths. For the comparison we have fit all-sky one-component dust models with fixed or variable emissivity spectral index to a new and improved version of the 210-channel dust spectra from the COBE-FIRAS, the 100-240 micrometer maps from the COBE-DIRBE and the 94 GHz dust map from the WMAP. The best model, the free-alpha model, is well constrained by data at 60-3000 GHz over 86 per cent of the total sky area. It predicts dust temperature (T(sub dust)) to be 13.7-22.7 (plus or minus 1.3) K, the emissivity spectral index (alpha) to be 1.2-3.1 (plus or minus 0.3) and the optical depth (tau) to range 0.6-46 x 10(exp -5) with a 23 per cent uncertainty. Using these estimates, we present all-sky evidence for an inverse correlation between the emissivity spectral index and dust temperature, which fits the relation alpha = 1/(delta + omega (raised dot) T(sub dust) with delta = -.0.510 plus or minus 0.011 and omega = 0.059 plus or minus 0.001. This best model will be useful to cosmic microwave background experiments for removing foreground dust contamination and it can serve as an all-sky extended-frequency reference for future higher resolution dust models.

  7. Pair Cascades and Deathlines in Magnetic Fields with Offset Polar Caps

    Science.gov (United States)

    Harding, Alice K.; Muslimov, Alex G.

    2012-01-01

    We present results of electron-positron pair cascade simulations in a dipole magnetic field whose polar cap is offset from the dipole axis. In such a field geometry, the polar cap is displaced a small fraction of the neutron star radius from the star symmetry axis and the field line radius of curvature is modified. Using the modified parallel electric field near the offset polar cap, we simulate pair cascades to determine the pair deathlines and pair multiplicities as a function of the offset. We find that the pair multiplicity can change dr;unatically with a modest offset, with a significant increase on one side of the polar cap. Lower pair deathlines allow a larger fraction of the pulsar population, that include old and millisecond pulsars, to produce cascades with high multiplicity. The results have some important implications for pulsar particle production, high-energy emission and cosmic-ray contribution.

  8. An onboard data analysis method to track the seasonal polar caps on Mars

    Science.gov (United States)

    Wagstaff, K.L.; Castano, R.; Chien, S.; Ivanov, A.B.; Pounders, E.; Titus, T.N.; ,

    2005-01-01

    The Martian seasonal CO2 ice caps advance and retreat each year. They are currently studied using instruments such as the THermal EMission Imaging System (THEMIS), a visible and infra-red camera on the Mars Odyssey spacecraft [1]. However, each image must be downlinked to Earth prior to analysis. In contrast, we have developed the Bimodal Image Temperature (BIT) histogram analysis method for onboard detection of the cap edge, before transmission. In downlink-limited scenarios when the entire image cannot be transmitted, the location of the cap edge can still be identified and sent to Earth. In this paper, we evaluate our method on uncalibrated THEMIS data and find 1) agreement with manual cap edge identifications to within 28.2 km, and 2) high accuracy even with a smaller analysis window, yielding large reductions in memory requirements. This algorithm is currently being considered as a capability enhancement for the Odyssey second extended mission, beginning in fall 2006.

  9. Thermal stability and optical properties of HMTA capped zinc sulfide nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Anand, K. Vijai [Department of Physics, Presidency College, Chennai 600005 (India); Department of Physics, Sathyabama University, Chennai 600119 (India); Chinnu, M. Karl [Centre for Nanoscience and Technology, Anna University, Chennai 600025 (India); Department of Physics, S.A. Engineering College, Chennai 600077 (India); Kumar, R. Mohan; Mohan, R. [Department of Physics, Presidency College, Chennai 600005 (India); Jayavel, R., E-mail: rjvel@annauniv.ed [Centre for Nanoscience and Technology, Anna University, Chennai 600025 (India)

    2010-04-30

    ZnS nanoparticles have been synthesized on a large scale by hydrothermal route using Hexamethylenetetramine (HMTA) as capping agent in aqueous solution. The average grain size of the nanoparticles calculated from the XRD pattern using Scherrer's formula is about 2-3 nm, which exhibit cubic zinc blende structure. TEM results showed that the synthesized nanoparticles were uniformly dispersed in the HMTA matrix without aggregation. The UV-vis absorption results revealed that the synthesized HMTA capped ZnS nanoparticles exhibit strong quantum confinement effect as the optical energy band gap increased significantly compared to the uncapped and bulk ZnS. Formation of HMTA capped ZnS nanoparticles was confirmed by FTIR studies. Emission spectra show that the HMTA capping not only increases the PL intensity, but also greatly improves the thermal stability of the ZnS nanoparticles.

  10. ATLAS electromagnetic end-cap detector

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    After the insertion of the first end-cap into this cryostat, the team proceed to the wiring operations. Millions of wires are connected to the electromagnetic calorimeter on this end-cap, whch must be carefully fed out from the detector so that data can be read out. The energy of photons, electrons and positrons will be measured as they pass through the end-cap having been created along the line of the beams in the proton-proton collisions.

  11. H-alpha Photometry of Abell 2390

    CERN Document Server

    Balogh, M L; Balogh, Michael L.; Morris, Simon L.

    2000-01-01

    We present the results of a search for strong H-alpha emission line galaxies (rest frame equivalent widths greater than 50 A) in the z=0.23 cluster Abell 2390. The survey contains 1189 galaxies over 270 square arcminutes, and is 50% complete at M_r=-17.5+5 log h. The fraction of galaxies in which H-alpha is detected at the 2sigma level rises from 0.0 in the central regions (excluding the cD galaxy) to 12.5+/-8% at R200. For 165 of the galaxies in our catalogue, we compare the H-alpha equivalent widths with their [OII] equivalent widths, from the CNOC1 spectra. The fraction of strong H-alpha emission line galaxies is consistent with the fraction of strong [OII] emission galaxies in the CNOC1 sample: only 2+/-1% have no detectable [OII] emission and yet significant (>2sigma) H-alpha equivalent widths. Dust obscuration, non-thermal ionization, and aperture effects are all likely to contribute to this non-correspondence of emission lines. We identify six spectroscopically 'secure' k+a galaxies (W(OII)5 A); at lea...

  12. Synthesis, Characterization, and Tribological Behavior of Oleic Acid Capped Graphene Oxide

    Directory of Open Access Journals (Sweden)

    Tiedan Chen

    2014-01-01

    Full Text Available Graphene oxide (GO nanosheets were prepared by modified Hummers and Offeman methods. Furthermore, oleic acid (OA capped graphene oxide (OACGO nanosheets were prepared and characterized by means of Fourier transform-infrared spectroscopy (FT-IR, transmission electron microscopy (TEM, and X-ray diffraction (XRD. At the same time, the friction and wear properties of OA capped graphite powder (OACG, OACGO, and oleic acid capped precipitate of graphite (OACPG as additives in poly-alpha-olefin (PAO were compared using four-ball tester and SRV-1 reciprocating ball-on-disc friction and wear tester. By the addition of OACGO to PAO, the antiwear ability was improved and the friction coefficient was decreased. Also, the tribological mechanism of the GO was investigated.

  13. Height stabilization of GaSb/GaAs quantum dots by Al-rich capping

    Directory of Open Access Journals (Sweden)

    E. P. Smakman

    2014-09-01

    Full Text Available GaSb quantum dots (QDs in a GaAs matrix are investigated with cross-sectional scanning tunneling microscopy (X-STM and photoluminescence (PL. We observe that Al-rich capping materials prevent destabilization of the nanostructures during the capping stage of the molecular beam epitaxy (MBE growth process and thus preserves the QD height. However, the strain induced by the absence of destabilization causes many structural defects to appear around the preserved QDs. These defects originate from misfit dislocations near the GaSb/GaAs interface and extend into the capping layer as stacking faults. The lack of a red shift in the QD PL suggests that the preserved dots do not contribute to the emission spectra. We suggest that a better control over the emission wavelength and an increase of the PL intensity is attainable by growing smaller QDs with an Al-rich overgrowth.

  14. Height stabilization of GaSb/GaAs quantum dots by Al-rich capping

    Energy Technology Data Exchange (ETDEWEB)

    Smakman, E. P., E-mail: e.p.smakman@tue.nl; Koenraad, P. M. [Department of Applied Physics, Eindhoven University of Technology, Den Dolech 2, 5612 AZ Eindhoven (Netherlands); DeJarld, M.; Martin, A. J.; Millunchick, J. [Department of Material Science and Engineering, University of Michigan, Ann Arbor, Michigan 48109 (United States); Luengo-Kovac, M.; Sih, V. [Department of Physics, University of Michigan, Ann Arbor, Michigan 48109 (United States)

    2014-09-01

    GaSb quantum dots (QDs) in a GaAs matrix are investigated with cross-sectional scanning tunneling microscopy (X-STM) and photoluminescence (PL). We observe that Al-rich capping materials prevent destabilization of the nanostructures during the capping stage of the molecular beam epitaxy (MBE) growth process and thus preserves the QD height. However, the strain induced by the absence of destabilization causes many structural defects to appear around the preserved QDs. These defects originate from misfit dislocations near the GaSb/GaAs interface and extend into the capping layer as stacking faults. The lack of a red shift in the QD PL suggests that the preserved dots do not contribute to the emission spectra. We suggest that a better control over the emission wavelength and an increase of the PL intensity is attainable by growing smaller QDs with an Al-rich overgrowth.

  15. Population Files for use with CAP88 at Los Alamos

    Energy Technology Data Exchange (ETDEWEB)

    McNaughton, Michael W [Los Alamos National Laboratory; Brock, Burgandy R [Los Alamos National Laboratory

    2012-07-10

    CAP88 (Clean Air Act Assessment Package 1988) is a computer model developed for the US Environmental Protection Agency to assess the potential dose from radionuclide emissions to air and to demonstrate compliance with the Clean Air Act. It has options to calculate either individual doses, in units of mrem, or a collective dose, also called population dose, in units of person-rem. To calculate the collective dose, CAP88 uses a population file such as LANL.pop, that lists the number of people in each sector (N, NNE, NE, etc.) as a function of distance (1 to 2 km, etc.) out to a maximum radius of 80 km. Early population files are described in the Los Alamos National Laboratory (LANL) Environmental Reports for 1985 (page 14) and subsequent years. LA-13469-MS describes a population file based on the 1990 census. These files have been updated several times, most recently in 2006 for CAP88 version 3. The 2006 version used the US census for 2000. The present paper describes the 2012 updates, using the 2010 census.

  16. Adjusting the CO2 cap to subsidised RES generation: Can CO2 prices be decoupled from renewable policy?

    NARCIS (Netherlands)

    Richstein, J.C.; Chappin, E.J.L.; De Vries, L.J.

    2015-01-01

    The low prices in the European Emission Trading System (EU ETS) have triggered discussions of various possible reforms. One option is to decouple the CO 2 prices from renewable energy policy by adjusting the emission cap to renewable energy investment overshoots. We introduce two ways of reducing th

  17. Nature mangement, landscape and the CAP

    NARCIS (Netherlands)

    Brouwer, F.M.; Godeschalk, F.E.

    2004-01-01

    The integration of nature management, landscape and environmental concerns into the Common Agricultural Policy (CAP) has gained momentum with the CAP reforms adopted in June 2003. The report explores instruments and approaches that contribute to the inte-gration of nature conservation and landscape

  18. ALEPH end-cap and barrel

    CERN Multimedia

    Patrice Loiez

    1993-01-01

    The end-cap is pulled away from the barrel on the ALEPH detector so that the hadronic calorimeter and muon chambers are revealed. The end-cap maximises the data available from particles produced along the direction of the beam. The workers on the inner part of the detector give a sense of scale.

  19. Photodegradation of luminescence in organic-ligand-capped Eu{sup 3+}:LaF{sub 3} nano-particles

    Energy Technology Data Exchange (ETDEWEB)

    King, Gavin G. G.; Taylor, Luke R.; Longdell, Jevon J., E-mail: jevon.longdell@otago.ac.nz [Department of Physics, University of Otago, P.O. Box 56, Dunedin 9054 (New Zealand); Clarke, David J.; Quilty, J. W. [Callaghan Innovation Research Limited, P.O. Box 31-310, Lower Hutt 5040 (New Zealand)

    2014-01-28

    The luminescence from europium doped lanthanum trifluoride (Eu{sup 3+}:LaF{sub 3}) nano-crystals can be greatly enhanced by capping with β-diketonate organic ligands. Here, we report on photo-stability measurements for the case of nano-crystals capped with thenoyltrifluroacetone (TTA) and compared with those capped with an inactive ligand, oleic acid. With exposure to UV pump light, we observed significant decrease in fluorescence and change in emission spectrum of the TTA-capped nano-particles whilst the fluorescence lifetime remained approximately constant. After a dose of order 70 kJ cm{sup −2}, the luminescence level was similar to that of oleic acid capped nano-crystals. We discuss possible mechanisms.

  20. Price caps and price floors in climate policy: a quantitative assessment

    Energy Technology Data Exchange (ETDEWEB)

    Philibert, Cedric

    2008-12-15

    This study assesses the long-term economic and environmental effects of introducing price caps and price floors in hypothetical climate change mitigation architecture, which aims to reduce global energy-related CO2 emissions by 50% by 2050. Based on abatement costs in IPCC and IEA reports, this quantitative analysis confirms what qualitative analyses have already suggested: introducing price caps could significantly reduce economic uncertainty. This uncertainty stems primarily from unpredictable economic growth and energy prices, and ultimately unabated emission trends. In addition, the development of abatement technologies is uncertain. With price caps, the expected costs could be reduced by about 50% and the uncertainty on economic costs could be one order of magnitude lower. Reducing economic uncertainties may spur the adoption of more ambitious policies by helping to alleviate policy makers' concerns of economic risks. Meanwhile, price floors would reduce the level of emissions beyond the objective if the abatement costs ended up lower than forecasted. If caps and floors are commensurate with the ambition of the policy pursued and combined with slightly tightened emission objectives, climatic results could be on average similar to those achieved with 'straight' objectives (i.e. with no cost-containment mechanism). (auth)

  1. Implications of carbon cap-and-trade for US voluntary renewable energy markets

    Energy Technology Data Exchange (ETDEWEB)

    Bird, Lori A. [National Renewable Energy Laboratory, 1617 Cole Boulevard, Golden, CO 80401 (United States); Holt, Edward [Ed Holt and Associates, Inc., 28 Headland Road, Harpswell, ME 04079-2923 (United States); Levenstein Carroll, Ghita [University of Colorado at Boulder, 3315 Folsom Street, Boulder, CO 80304 (United States)

    2008-06-15

    Many consumers today are purchasing renewable energy in large part for the greenhouse gas (GHG) emissions benefits that they provide. Emerging carbon regulation in the US has the potential to affect existing markets for renewable energy. Carbon cap-and-trade programs are now under development in the Northeast under the Regional Greenhouse Gas Initiative (RGGI) and in early stages of development in the West and Midwest. There is increasing discussion about carbon regulation at the national level as well. While renewable energy will likely benefit from carbon cap-and-trade programs because compliance with the cap will increase the costs of fossil fuel generation, cap-and-trade programs can also impact the ability of renewable energy generation to affect overall CO{sub 2} emissions levels and obtain value for those emissions benefits. This paper summarizes key issues for renewable energy markets that are emerging with carbon regulation, such as the implications for emissions benefits claims and voluntary market demand and the use of renewable energy certificates (RECs) in multiple markets. It also explores policy options under consideration for designing carbon policies to enable carbon markets and renewable energy markets to work together. (author)

  2. Ferromagnetism of polythiophene-capped Au nanoparticles

    Science.gov (United States)

    Suzuki, K.; Zhang, H.; Saito, K.; Garitaonandia, J. S.; Goikolea, E.; Insausti, M.

    2011-04-01

    The magnetic and electrical transport properties of regioregular poly(3-hexylthiophene)-capped Au nanoparticles (NPs) doped with iodine have been investigated to clarify the effectiveness of conductive polymer capping on the induction of ferromagnetism in Au. The room-temperature magnetization curve of the undoped polythiophene-capped Au NPs exhibits a clear hysteresis behavior with a coercive force of 160 Oe. The spontaneous magnetization normalized by the mass of Au is 2.0 × 10-2 emu/g. The spontaneous magnetization was found virtually unaffected by iodine doping, whereas the electrical conductivity is enhanced dramatically to ˜10 S/cm. Our results show that polythiophene capping could lead to spontaneous magnetic polarization in Au NPs, and the conductivity of the polymer capping does not affect the ferromagnetism of the Au nanoparticles, opening a possibility for further investigation into the magnetotransport behavior of ferromagnetic Au NPs.

  3. A temp erature and emissivity separation algorithm based on maximum entropy estimation of alpha sp ectrum’s scaling and translation%基于最大熵估计Alpha谱缩放与平移量的温度与发射率分离算法∗

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    In the thermal infrared (TIR) waveband, solving the target emissivity spectrum and temperature leads to an ill-posed problem in which the number of unknown parameters is larger than that of available measurements. Generally, the approaches developed for solving this kind of problems are called, by a joint name, the TES (temperature and emissivity separation) algorithm. As is shown in the name, the TES algorithm is dedicated to separating the target temperature and emissivity in the calculating procedure. In this paper, a novel method called the new MaxEnt (maximum entropy) TES algorithm is proposed, which is considered as a promotion of the MaxEnt TES algorithm proposed by Barducci. The maximum entropy estimation is utilized as the basic framework in the two preceding algorithms, so that the two algorithms both could make temperature and emissivity separation, independent of experiential information derived by some special data bases. As a result, the two algorithms could be applied to solve the temperature and emissivity spectrum of the targets which are absolutely unknown to us. However, what makes the two algorithms different is that the alpha spectrum derived by the ADE (alpha derived emissivity) method is considered as priori information to be added in the new MaxEnt TES algorithm. Based on the Wien approximation, the ADE method is dedicated to the calculation of the alpha spectrum which has a similar distribution to the true emissivity spectrum. Based on the preceding promotion, the new MaxEnt TES algorithm keeps a simpler mathematical formalism. Without any doubt, the new MaxEnt TES algorithm provides a faster computation for large volumes of data (i.e. hyperspectral images of the Earth). Some numerical simulations have been performed; the data and results show that, the maximum RMSE of emissivity estimation is 0.017, the maximum absolute error of temperature estimation is 0.62 K. Added with Gaussian white noise in which the signal to noise ratio is measured

  4. Characterization of Mars' seasonal caps using neutron spectroscopy

    Science.gov (United States)

    Prettyman, T.H.; Feldman, W.C.; Titus, T.N.

    2009-01-01

    Mars' seasonal caps are characterized during Mars years 26 and 27 (April 2002 to January 2006) using data acquired by the 2001 Mars Odyssey Neutron Spectrometer. Time-dependent maps of the column abundance of seasonal CO 2 surface ice poleward of 60?? latitude in both hemispheres are determined from spatially deconvolved, epithermal neutron counting data. Sources of systematic error are analyzed, including spatial blurring by the spectrometer's broad footprint and the seasonal variations in the abundance of noncondensable gas at high southern latitudes, which are found to be consistent with results reported by Sprague et al. (2004, 2007). Corrections for spatial blurring are found to be important during the recession, when the column abundance of seasonal CO2 ice has the largest latitude gradient. The measured distribution and inventory of seasonal CO2 ice is compared to simulations by a general circulation model (GCM) calibrated using Viking lander pressure data, cap edge functions determined by thermal emission spectroscopy, and other nuclear spectroscopy data sets. On the basis of the amount of CO2 cycled through the caps during years 26 and 27, the gross polar energy balance has not changed significantly since Viking. The distribution of seasonal CO2 ice is longitudinally asymmetric: in the north, deposition rates of CO2 ice are elevated in Acidalia, which is exposed to katabatic winds from Chasma Borealis; in the south, CO2 deposition is highest near the residual cap. During southern recession, CO 2 ice is present longer than calculated by the GCM, which has implications for the local polar energy balance. Copyright 2009 by the American Geophysical Union.

  5. Ab initio alpha-alpha scattering

    CERN Document Server

    Elhatisari, Serdar; Rupak, Gautam; Epelbaum, Evgeny; Krebs, Hermann; Lähde, Timo A; Luu, Thomas; Meißner, Ulf-G

    2015-01-01

    Processes involving alpha particles and alpha-like nuclei comprise a major part of stellar nucleosynthesis and hypothesized mechanisms for thermonuclear supernovae. In an effort towards understanding alpha processes from first principles, we describe in this letter the first ab initio calculation of alpha-alpha scattering. We use lattice effective field theory to describe the low-energy interactions of nucleons and apply a technique called the adiabatic projection method to reduce the eight-body system to an effective two-cluster system. We find good agreement between lattice results and experimental phase shifts for S-wave and D-wave scattering. The computational scaling with particle number suggests that alpha processes involving heavier nuclei are also within reach in the near future.

  6. The pharmaceutical vial capping process: Container closure systems, capping equipment, regulatory framework, and seal quality tests.

    Science.gov (United States)

    Mathaes, Roman; Mahler, Hanns-Christian; Buettiker, Jean-Pierre; Roehl, Holger; Lam, Philippe; Brown, Helen; Luemkemann, Joerg; Adler, Michael; Huwyler, Joerg; Streubel, Alexander; Mohl, Silke

    2016-02-01

    Parenteral drug products are protected by appropriate primary packaging to protect against environmental factors, including potential microbial contamination during shelf life duration. The most commonly used CCS configuration for parenteral drug products is the glass vial, sealed with a rubber stopper and an aluminum crimp cap. In combination with an adequately designed and controlled aseptic fill/finish processes, a well-designed and characterized capping process is indispensable to ensure product quality and integrity and to minimize rejections during the manufacturing process. In this review, the health authority requirements and expectations related to container closure system quality and container closure integrity are summarized. The pharmaceutical vial, the rubber stopper, and the crimp cap are described. Different capping techniques are critically compared: The most common capping equipment with a rotating capping plate produces the lowest amount of particle. The strength and challenges of methods to control the capping process are discussed. The residual seal force method can characterize the capping process independent of the used capping equipment or CCS. We analyze the root causes of several cosmetic defects associated with the vial capping process.

  7. Capping stack: An industry in the making

    Institute of Scientific and Technical Information of China (English)

    Jack Chen; Li Xunke; Xie Wenhui; Kang Yongtian

    2013-01-01

    This paper gives an overview of recent development of the marine well containment system (MWCS)after BP Macondo subsea well blowout occurred on April 20,2010 in the Gulf of Mexico.Capping stack,a hardware utilized to contain blowout well at or near the wellhead is the center piece of MWCS.Accessibility to the dedicated capping stacks is gradually becoming a pre-requirement to obtain the permit for offshore drilling/workover,and the industry for manufacturing,maintenance,transportation and operation of the capping stack is in the making.

  8. Disc-Capped ZnO Nanocombs

    Institute of Scientific and Technical Information of China (English)

    LI Xin; XU chun-xiang; ZHU Guang-Ping; YANG Yi; LIU Jin-Ping; SUN Xiao-Wei; CUI Yi-Ping

    2007-01-01

    Nanocombs with a disc cap structure of ZnO have been synthesized on si substrates by using pure Zinc powders as the source materials based on a vapour-phase transport process.The morphology and the microstructure are investigated by a scanning electron microscopy and x-ray diffraction.Based on the transmission electron microscopy and selected area electron diffraction analysis,the growth directions of three representative parts,nanoribbon stem,nanorod branch and nanodisc cap of the nanocomb are revealed.The growth mechanism of the disc-capped nanocombs is discussed based on the self-catalyzed vapour-liquid-solid process.

  9. Tumor necrosis factor induces phosphorylation of a 28-kDa mRNA cap-binding protein in human cervical carcinoma cells

    Energy Technology Data Exchange (ETDEWEB)

    Marino, M.W.; Guidon, P.T. Jr.; Donner, D.B. (Cornell Univ. Graduate School of Medical Sciences, New York, NY (USA)); Pfeffer, L.M. (Rockefeller Univ., New York, NY (USA))

    1989-11-01

    Tumor necrosis factor {alpha} (TNF-{alpha}) stimulated the phosphorylation of a 28-kDa protein (p28) in the ME-180 line of human cervical carcinoma cells. The effect of TNF-{alpha} on the phosphorylation state of p28 was rapid (4-fold increase within 15 min) and persistent, remaining above the basal level for at least 2 hr. The specific binding of {sup 125}I-labeled TNF-{alpha} to cell-surface binding sites, the stimulation of p28 phosphorylation by TNF-{alpha}, and the inhibition of cell proliferation by TNF-{alpha} occurred with nearly identical dose-response relationships. Two-dimensional SDS/PAGE resolved p28 into two isoforms having pI values of 6.2 and 6.1. A phosphorylated cap-binding protein was substantially enriched from lysates of control or TNF-{alpha}-treated ME-180 cells by affinity chromatography with 7-methylguanosine 5{prime}-triposphate-Sepharose. The phosphoprotein recovered from this procedure was the substrate for TNF-{alpha}-promoted phosphorylation, p28. Thus, TNF-{alpha} stimulates the phosphorylation of this mRNA cap-binding protein, which may be involved in the transduction of TNF-{alpha}-receptor binding into cellular responses.

  10. Tumor necrosis factor induces phosphorylation of a 28-kDa mRNA cap-binding protein in human cervical carcinoma cells.

    Science.gov (United States)

    Marino, M W; Pfeffer, L M; Guidon, P T; Donner, D B

    1989-11-01

    Tumor necrosis factor alpha (TNF-alpha) stimulated the phosphorylation of a 28-kDa protein (p28) in the ME-180 line of human cervical carcinoma cells. The effect of TNF-alpha on the phosphorylation state of p28 was rapid (4-fold increase within 15 min) and persistent, remaining above the basal level for at least 2 hr. The specific binding of 125I-labeled TNF-alpha to cell-surface binding sites, the stimulation of p28 phosphorylation by TNF-alpha, and the inhibition of cell proliferation by TNF-alpha occurred with nearly identical dose-response relationships. Two-dimensional SDS/PAGE resolved p28 into two isoforms having pI values of 6.2 and 6.1. A phosphorylated cap-binding protein was substantially enriched from lysates of control or TNF-alpha-treated ME-180 cells by affinity chromatography with 7-methylguanosine 5'-triphosphate-Sepharose. The phosphoprotein recovered from this procedure was the substrate for TNF-alpha-promoted phosphorylation, p28. Thus, TNF-alpha stimulates the phosphorylation of this mRNA cap-binding protein, which may be involved in the transduction of TNF-alpha-receptor binding into cellular responses.

  11. The disintegration of GaSb/GaAs nanostructures upon capping

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Andrew J; Jinyoung, Hwang; Marquis, Emmanuelle A; Smakman, Erwin; Saucer, Timothy W; Rodriguez, Garrett; Hunter, Allen H; Sih, Vanessa; Koenraad, Paul M; Phillips, Jamie D.; Millunchick, Joanna M

    2013-01-01

    Atom probe tomography and cross-sectional scanning tunneling microscopy show that GaSb/GaAs quantum dots disintegrate into ring-like clusters of islands upon capping. Band transition energies calculated using an 8-band k.p model of the capped dots with the observed dimensions are consistent with emission energies observed in photoluminescence data. These results emphasize the need for full three-dimensional characterization to develop an accurate understanding of the structure, and thus the optical properties, of buried quantum dots.

  12. Double-real corrections at O(alpha alpha_s) to single gauge boson production

    CERN Document Server

    Bonciani, Roberto; Mondini, Roberto; Vicini, Alessandro

    2016-01-01

    We consider the O(alpha alpha_s) corrections to single on-shell gauge boson production at hadron colliders. We concentrate on the contribution of all the subprocesses where the gauge boson is accompanied by the emission of two additional real partons and we evaluate the corresponding total cross sections. The latter are divergent quantities, because of soft and collinear emissions, and are expressed as Laurent series in the dimensional regularization parameter. The total cross sections are evaluated by means of reverse unitarity, i.e. expressing the phase-space integrals in terms of two-loop forward box integrals with cuts on the final state particles. The results are reduced to a combination of Master Integrals, which eventually are evaluated in terms of Generalized Polylogarithms. The presence of internal massive lines in the Feynman diagrams, due to the exchange of electroweak gauge bosons, causes the appearance of 14 Master Integrals which were not previously known in the literature and have been evaluate...

  13. C-CAP Land Cover, Kauai, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  14. C-CAP Land Cover, Maui, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  15. C-CAP Land Cover, Molokai, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  16. C-CAP Land Cover, Lanai, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  17. Circumpolar Active-Layer Permafrost System (CAPS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Circumpolar Active-Layer Permafrost System (CAPS) contains over 100 data sets pertaining to permafrost and frozen ground topics. It also contains detailed...

  18. C-CAP Hawaii 2005 Land Cover

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  19. Cryopyrin-Associated Autoinflammatory Syndromes (CAPS) - Juvenile

    Science.gov (United States)

    ... of the nervous system, including headaches and deafness. CAPS are not contagious. Treatments that block interleukin-1, an important molecule involved in the inflammatory process, are very effective. To prevent permanent damage, treatment ...

  20. C-CAP Land Cover, Niihau, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  1. C-CAP Niihau 2005 Land Cover

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land cover derived from high resolution imagery according to the Coastal Change Analysis Program (C-CAP) protocol. This data set utilized 1...

  2. Model for Formation of Martian Residual Cap Depressions (Swiss Cheese)

    Science.gov (United States)

    Byrne, S.; Ingersoll, A. P.

    2001-12-01

    In an effort for explain the formation of the `Swiss-cheese' terrain visible on the southern residual cap of Mars (Thomas et al., Nature, 404,2000); we have developed a radiative model to follow the growth/decay of an initial depression due to sublimation/condensation of carbon dioxide. The pits making up this terrain have many distinctive features; they are shallow (~10m deep), with steep walls and flat floors and contain an interior moat that runs along the bottom of the walls. Their diameters range from a few 10's of meters to a kilometer. The model accounts for incident sunlight, emitted thermal radiation, and scattered short and long wave radiation. We have included the effects of a layer of water ice placed under the carbon dioxide at adjustable depth. The water ice layer is free to store heat during the summer (when the carbon dioxide has been removed) through subsurface diffusion of heat. Release of this heat at the end of the summer can inhibit frost formation. We have investigated many cases involving pure dry ice with constant albedo, albedo as a function of insolation, and differing albedo for fresh and residual frost (the latter has lower albedo). In most cases the initial depressions heal themselves and disappear into the surrounding terrain. Cases involving the layer of water ice provide a much closer approximation to the shape of the observed features (especially the flat bottoms). A problem arises of how much exposed water ice we can have during the summer season and still have temperatures averaged over the footprint of the Thermal Emission Spectrometer be close to the carbon dioxide sublimation temperatures. The depth to the water ice layer is a strong controlling factor of the evolution of depression shape and depth in our model. Matching this shape with observations yields important information regarding the depth to any putative water ice layer within the residual cap itself. It is known from laboratory measurements that carbon dioxide is too

  3. Righting an ATLAS end-cap

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Each component of the giant ATLAS detector must be moved and transported with great caution so that delicate components are not damaged. Therefore, tests are performed, like the one shown. The end-cap weighs 160 tonnes, making the delicate moving process a non-trivial feat. A special crane and supports have been designed so that the end-cap can be raised using a pivot.

  4. Design and implementation of the CAPS receiver

    Science.gov (United States)

    Hu, Yonghui; Hua, Yu; Hou, Lei; Wei, Jingfa; Wu, Jianfeng

    2009-03-01

    In this paper, based on analyses of the Chinese Area Positioning System (CAPS) satellite (GEO satellite) resources and signal properties, the signal power at the port of the receiver antenna is estimated, and the implementation projects are presented for a switching band C to band L CAPS C/A code receiver integrated with GPS receiver suite and for a CAPS dual frequency P code receiver. A microstrip receiving antenna is designed with high sensitivity and wide beam orientation, the RF front end of the C/A code and P code receivers, and a processor is designed for the navigation baseband. A single frequency CAPS C/A code receiver and a CAPS dual frequency P code receiver are built at the same time. A software process flow is provided, and research on relatively key techniques is also conducted, such as signal searching, code loop and carrier loop algorithms, a height assistant algorithm, a dual frequency difference speed measurement technique, a speed measurement technique using a single frequency source with frequency assistance, and a CAPS time correcting algorithm, according to the design frame of the receiver hardware. Research results show that the static plane positioning accuracy of the CAPS C/A code receiver is 20.5-24.6 m, height accuracy is 1.2-12.8 m, speed measurement accuracy is 0.13-0.3 m/s, dynamic plane positioning accuracy is 24.4 m, height accuracy is 3.0 m, and speed measurement accuracy is 0.24 m/s. In the case of C/A code, the timing accuracy is 200 ns, and it is also shown that the positioning accuracy of the CAPS precise code receiver (1 σ) is 5 m from south to north, and 0.8 m from east to west. Finally, research on positioning accuracy is also conducted.

  5. Design and implementation of the CAPS receiver

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In this paper, based on analyses of the Chinese Area Positioning System (CAPS) satellite (GEO satellite) resources and signal properties, the signal power at the port of the receiver antenna is estimated, and the implementation projects are presented for a switching band C to band L CAPS C/A code receiver integrated with GPS receiver suite and for a CAPS dual frequency P code receiver. A microstrip receiving antenna is designed with high sensitivity and wide beam orientation, the RF front end of the C/A code and P code receivers, and a processor is designed for the navigation baseband. A single frequency CAPS C/A code receiver and a CAPS dual frequency P code receiver are built at the same time. A software process flow is provided, and research on relatively key techniques is also conducted, such as signal searching, code loop and carrier loop algorithms, a height assistant algorithm, a dual frequency difference speed measurement technique, a speed measurement technique using a single frequency source with frequency assistance, and a CAPS time correcting algorithm, according to the design frame of the receiver hardware. Research results show that the static plane positioning accuracy of the CAPS C/A code receiver is 20.5-24.6 m, height accuracy is 1.2-12.8 m, speed measurement accuracy is 0.13-0.3 m/s, dynamic plane positioning accuracy is 24.4 m, height accuracy is 3.0 m, and speed measurement accuracy is 0.24 m/s. In the case of C/A code, the timing accuracy is 200 ns, and it is also shown that the positioning accuracy of the CAPS precise code receiver (1σ ) is 5 m from south to north, and 0.8 m from east to west. Finally, research on positioning accuracy is also conducted.

  6. Faddeev calculation of 3 alpha and alpha alpha Lambda systems using alpha alpha resonating-group method kernel

    CERN Document Server

    Fujiwara, Y; Kohno, M; Suzuki, Y; Baye, D; Sparenberg, J M

    2004-01-01

    We carry out Faddeev calculations of three-alpha (3 alpha) and two-alpha plus Lambda (alpha alpha Lambda) systems, using two-cluster resonating-group method kernels. The input includes an effective two-nucleon force for the alpha alpha resonating-group method and a new effective Lambda N force for the Lambda alpha interaction. The latter force is a simple two-range Gaussian potential for each spin-singlet and triplet state, generated from the phase-shift behavior of the quark-model hyperon-nucleon interaction, fss2, by using an inversion method based on supersymmetric quantum mechanics. Owing to the exact treatment of the Pauli-forbidden states between the clusters, the present three-cluster Faddeev formalism can describe the mutually related, alpha alpha, 3 alpha and alpha alpha Lambda systems, in terms of a unique set of the baryon-baryon interactions. For the three-range Minnesota force which describes the alpha alpha phase shifts quite accurately, the ground-state and excitation energies of 9Be Lambda are...

  7. Ly$\\alpha$ and UV Sizes of Green Pea Galaxies

    CERN Document Server

    Yang, Huan; Rhoads, James E; Leitherer, Claus; Wofford, Aida; Jiang, Tianxing; Wang, Junxian

    2016-01-01

    Green Peas are nearby analogs of high-redshift Ly$\\alpha$-emitting galaxies. To probe their Ly$\\alpha$ escape, we study the spatial profiles of Ly$\\alpha$ and UV continuum emission of 24 Green Pea galaxies using the Cosmic Origins Spectrograph (COS) on Hubble Space Telescope (HST). We extract the spatial profiles of Ly$\\alpha$ emission from their 2D COS spectra, and of UV continuum from both the 2D spectra and NUV images. The Ly$\\alpha$ emission shows more extended spatial profiles than the UV continuum in most Green Peas. The deconvolved Full Width Half Maximum (FWHM) of the Ly$\\alpha$ spatial profile is about 2 to 4 times that of the UV continuum in most cases. The Ly$\\alpha$ light shows significant offsets from the UV continuum in four galaxies and central absorption in one galaxy. We also compare the spatial profiles of Ly$\\alpha$ photons at blueshifted and redshifted velocities in eight Green Peas with sufficient data quality, and find the blue wing of the Ly$\\alpha$ line has a larger spatial extent than...

  8. 42 CFR 418.309 - Hospice cap amount.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Hospice cap amount. 418.309 Section 418.309 Public...) MEDICARE PROGRAM HOSPICE CARE Payment for Hospice Care § 418.309 Hospice cap amount. The hospice cap amount... until October 31 of the following year. (b) Each hospice's cap amount is calculated by the...

  9. Growth and properties of ultra-violet emitting aligned zinc oxide nanocones with hexagonal caps.

    Science.gov (United States)

    Umar, Ahmad; Al Hajry, A; Al-Ghamdi, A A; Al-Heniti, S

    2010-10-01

    Ultraviolet-emitting, single-crystalline aligned zinc oxide (ZnO) nanocones with hexagonal caps were grown on silicon substrate via simple non-catalytic thermal evaporation process. High-purity metallic zinc powder and oxygen were used as source materials for zinc and oxygen, respectively. The detailed structural characterizations confirmed that the formed products are single-crystalline, possess a wurtzite hexagonal phase and grown along the c-axis direction. Raman-active optical-phonon E2(high) mode at 437 cm(-1) with sharp and strong UV emission at 385 nm in room-temperature photoluminescence (PL) spectrum demonstrated that the as-grown ZnO nanocones with hexagonal caps possess good-crystal quality with the excellent optical properties. Finally, a plausible growth mechanism for the formation of as-grown ZnO nanocones with hexagonal caps was also proposed.

  10. 75 FR 49527 - Caps Visual Communications, LLC; Black Dot Group; Formerly Known as Caps Group Acquisition, LLC...

    Science.gov (United States)

    2010-08-13

    ... Employment and Training Administration Caps Visual Communications, LLC; Black Dot Group; Formerly Known as... Adjustment Assistance on June 24, 2010, applicable to workers of Caps Visual Communications, LLC, Black Dot..., Caps Visual Communications, LLC, Black Dot Group, formerly known as Caps Group Acquisition,...

  11. Scenarios for a cap beyond 2013; Implications for EU27 agriculture and the cap budget

    NARCIS (Netherlands)

    Helming, J.F.M.; Terluin, I.J.

    2011-01-01

    An ex ante analysis of a set of five policy components (proposed post 2013 CAP measures) has been carried out for the 2014-2020 period, based on the EC Communication The CAP towards 2020 of 18 November 2010. The policy components are defined in such a way that they focus on the contribution of farme

  12. Storage of cellular 5' mRNA caps in P bodies for viral cap-snatching.

    Science.gov (United States)

    Mir, M A; Duran, W A; Hjelle, B L; Ye, C; Panganiban, A T

    2008-12-09

    The minus strand and ambisense segmented RNA viruses include multiple important human pathogens and are divided into three families, the Orthomyxoviridae, the Bunyaviridae, and the Arenaviridae. These viruses all initiate viral transcription through the process of "cap-snatching," which involves the acquisition of capped 5' oligonucleotides from cellular mRNA. Hantaviruses are emerging pathogenic viruses of the Bunyaviridae family that replicate in the cytoplasm of infected cells. Cellular mRNAs can be actively translated in polysomes or physically sequestered in cytoplasmic processing bodies (P bodies) where they are degraded or stored for subsequent translation. Here we show that the hantavirus nucleocapsid protein binds with high affinity to the 5' cap of cellular mRNAs, protecting the 5' cap from degradation. We also show that the hantavirus nucleocapsid protein accumulates in P bodies, where it sequesters protected 5' caps. P bodies then serve as a pool of primers during the initiation of viral mRNA synthesis by the viral polymerase. We propose that minus strand segmented viruses replicating in the cytoplasm have co-opted the normal degradation machinery of P bodies for storage of cellular caps. Our data also indicate that modification of the cap-snatching model is warranted to include a role for the nucleocapsid protein in cap acquisition and storage.

  13. Sustainable Trade Credit and Replenishment Policies under the Cap-And-Trade and Carbon Tax Regulations

    Directory of Open Access Journals (Sweden)

    Juanjuan Qin

    2015-12-01

    Full Text Available The paper considers the sustainable trade credit and inventory policies with demand related to credit period and the environmental sensitivity of consumers under the carbon cap-and-trade and carbon tax regulations. First, the decision models are constructed under three cases: without regulation, carbon cap-and-trade regulation, and carbon tax regulation. The optimal solutions of the retailer in the three cases are then discussed under the exogenous and endogenous credit periods. Finally, numerical analysis is conducted to obtain conclusions. The retailer shortens the trade credit period as the environmental sensitivity of the consumer is enhanced. The cap has no effects on the credit period decisions under the carbon cap-and-trade regulation. Carbon trade price and carbon tax have negative effects on the credit period. The retailer under carbon cap-and-trade regulation is more motivated to obey regulations than that under carbon tax regulation when carbon trade price equals carbon tax. Carbon regulations have better effects on carbon emission reduction than with exogenous credit term when the retailer has the power to decide with regards credit policies.

  14. Martian north polar cap summer water cycle

    CERN Document Server

    Brown, Adrian J; Becerra, Patricio; Byrne, Shane

    2016-01-01

    A key outstanding question in Martian science is 'are the polar caps gaining or losing mass and what are the implications for past, current and future climate?' To address this question, we use observations from the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) of the north polar cap during late summer for multiple Martian years, to monitor the summertime water cycle in order to place quantitative limits on the amount of water ice deposited and sublimed in late summer. We establish here for the first time the summer cycle of water ice absorption band signatures on the north polar cap. We show that in a key region in the interior of the north polar cap, the absorption band depths grow until Ls=120, when they begin to shrink, until they are obscured at the end of summer by the north polar hood. This behavior is transferable over the entire north polar cap, where in late summer regions 'flip' from being net sublimating into net condensation mode. This transition or 'mode flip' happens earlier for ...

  15. Analysis on the positioning precision of CAPS

    Institute of Scientific and Technical Information of China (English)

    JI YuanFa; SUN XiYan

    2009-01-01

    As a newly developed satellite positioning system,the Chinese Area Positioning System (CAPS) Is a typical direct sequence spread spectrum ranging system like GPS.The positioning precision of such navigation signals depends on many factors,including the pseudo-code rate,the signal to noise ratio,the processing methods for tracking loops and so on.This paper describes the CAPS link budget,the solution approach for CAPS positioning,focusing on the autocorrelation function feature of C/A code signals.The CAPS signal measurement precision is studied by the software approach together with theoretical analysis of the range resolution.Because the conventional Delay Lock Loop (DLL) is vulnerable to the impact of noise,a narrow correlator and multiple correlatore as well as the corresponding discrimination methods of phases are proposed,which improves the robustness of DLL and the code-phase resolution of the measurement.The results show that the Improvement of the DLL structure and the discrimination method are the most important way to improve the ranging resolution.Theoretical analysis and experimental results show that a CAPS receiver could reach a 20-m positioning precision by using three satellites with a supported height from an altimeter.

  16. Analysis on the positioning precision of CAPS

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    As a newly developed satellite positioning system, the Chinese Area Positioning System (CAPS) is a typical direct sequence spread spectrum ranging system like GPS. The positioning precision of such navigation signals depends on many factors, including the pseudo-code rate, the signal to noise ratio, the processing methods for tracking loops and so on. This paper describes the CAPS link budget, the solution approach for CAPS positioning, focusing on the autocorrelation function feature of C/A code signals. The CAPS signal measurement precision is studied by the software approach together with theoretical analysis of the range resolution. Because the conventional Delay Lock Loop (DLL) is vul- nerable to the impact of noise, a narrow correlator and multiple correlators as well as the corresponding discrimination methods of phases are proposed, which improves the robustness of DLL and the code-phase resolution of the measurement. The results show that the improvement of the DLL structure and the discrimination method are the most important way to improve the ranging resolution. Theoretical analysis and experimental results show that a CAPS receiver could reach a 20-m positioning precision by using three satellites with a supported height from an altimeter.

  17. Nasute termite soldier frontal gland secretions. 1. Structure of Trinervi-2. beta. ,3. cap alpha. ,9. cap alpha. -triol 9-O acetate, a novel diterpene from Trinervitermes soldiers

    Energy Technology Data Exchange (ETDEWEB)

    Prestwich, G.D. (International Center of Insect Physiology and Ecology, Nairobi, Kenya); Tanis, S.P.; Springer, J.P.; Clardy, J.

    1976-09-15

    One of the major constituents, ''TG-2,'' of the soldier secretions of Trinervitermes gratiosus Sjostedt were studied by x-ray diffraction. The structure was determined to be a novel diterpene skeleton with a bridgehead double bond in an 11-membered ring. Bond angles and lengths were discussed, and a computer generated perspective drawing of the compound was presented. (DDA)

  18. The determination of $\\alpha_s$ by the ALPHA collaboration

    CERN Document Server

    Bruno, Mattia; Fritzsch, Patrick; Korzec, Tomasz; Ramos, Alberto; Schaefer, Stefan; Simma, Hubert; Sint, Stefan; Sommer, Rainer

    2016-01-01

    We review the ALPHA collaboration strategy for obtaining the QCD coupling at high scale. In the three-flavor effective theory it avoids the use of perturbation theory at $\\alpha > 0.2$ and at the same time has the physical scales small compared to the cutoff $1/a$ in all stages of the computation. The result $\\Lambda_\\overline{MS}^{(3)}=332(14)$~MeV is translated to $\\alpha_\\overline{MS}(m_Z)=0.1179(10)(2)$ by use of (high order) perturbative relations between the effective theory couplings at the charm and beauty quark "thresholds". The error of this perturbative step is discussed and estimated as $0.0002$.

  19. On the Diffuse Lyman-alpha Halo Around Lyman-alpha Emitting Galaxies

    CERN Document Server

    Lake, Ethan; Cen, Renyue; Sadoun, Raphael; Momose, Rieko; Ouchi, Masami

    2015-01-01

    Ly$\\alpha$ photons scattered by neutral hydrogen atoms in the circumgalactic media or produced in the halos of star-forming galaxies are expected to lead to extended Ly$\\alpha$ emission around galaxies. Such low surface brightness Ly$\\alpha$ halos (LAHs) have been detected by stacking Ly$\\alpha$ images of high-redshift star-forming galaxies. We study the origin of LAHs by performing radiative transfer modeling of nine $z=3.1$ Lyman-Alpha Emitters (LAEs) in a high resolution hydrodynamic galaxy formation simulation. We develop a method of computing the mean Ly$\\alpha$ surface brightness profile of each LAE by effectively integrating over many different observing directions. Without adjusting any parameters, our model yields an average Ly$\\alpha$ surface brightness profile in remarkable agreement with observations. We find that observed LAHs can not be accounted for solely by photons originating from the central LAE and scattered to large radii by hydrogen atoms in the circumgalactic gas. Instead, Ly$\\alpha$ em...

  20. 76 FR 13851 - National Emission Standards for Hazardous Air Pollutants: Mercury Emissions From Mercury Cell...

    Science.gov (United States)

    2011-03-14

    ... mercury, and 287,000 tons per year of carbon dioxide (CO 2 ). Since nitrogen oxide (NOx) and sulfur dioxide (SO 2 ) are covered by capped emissions trading programs, we are only estimating PM 2.5 emission... stripped from the brine flow to the anode to form the chlorine product, and the sodium/potassium ions...

  1. Seismic explosion sources on an ice cap

    DEFF Research Database (Denmark)

    Shulgin, Alexey; Thybo, Hans

    2015-01-01

    Controlled source seismic investigation of crustal structure below ice covers is an emerging technique. We have recently conducted an explosive refraction/wide-angle reflection seismic experiment on the ice cap in east-central Greenland. The data-quality is high for all shot points and a full...... as a strong ice wave. The ice cap leads to low transmission of energy into the crust such that charges need be larger than in conventional onshore experiments to obtain reliable seismic signals. The strong reflection coefficient at the base of the ice generates strong multiples which may mask for secondary...... phases. This effect may be crucial for acquisition of reflection seismic profiles on ice caps. Our experience shows that it is essential to use optimum depth for the charges and to seal the boreholes carefully....

  2. Martian north polar cap summer water cycle

    Science.gov (United States)

    Brown, Adrian J.; Calvin, Wendy M.; Becerra, Patricio; Byrne, Shane

    2016-10-01

    A key outstanding question in Martian science is "are the polar caps gaining or losing mass and what are the implications for past, current and future climate?" To address this question, we use observations from the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) of the north polar cap during late summer for multiple Martian years, to monitor the summertime water cycle in order to place quantitative limits on the amount of water ice deposited and sublimed in late summer. We establish here for the first time the summer cycle of water ice absorption band signatures on the north polar cap. We show that in a key region in the interior of the north polar cap, the absorption band depths grow until Ls = 120, when they begin to shrink, until they are obscured at the end of summer by the north polar hood. This behavior is transferable over the entire north polar cap, where in late summer regions 'flip' from being net sublimating into net condensation mode. This transition or 'mode flip' happens earlier for regions closer to the pole, and later for regions close to the periphery of the cap. The observations and calculations presented herein estimate that on average a water ice layer ∼70 microns thick is deposited during the Ls = 135-164 period. This is far larger than the results of deposition on the south pole during summer, where an average layer 0.6-6 microns deep has been estimated by Brown et al. (2014) Earth Planet. Sci. Lett., 406, 102-109.

  3. Linking Ly-alpha and Low-Ionization Transitions at Low Optical Depth

    CERN Document Server

    Jaskot, A E

    2014-01-01

    We suggest that low optical depth in the Lyman continuum (LyC) may relate the Ly-alpha emission, C II and Si II absorption, and C II* and Si II* emission seen in high-redshift galaxies. We base this analysis on Hubble Space Telescope COS spectra of four Green Pea (GP) galaxies, which may be analogs of z>2 Ly-alpha emitters (LAEs). In the two GPs with the strongest Ly-alpha emission, the Ly-alpha line profiles do not show the typical effects of resonant scattering. Instead, the Ly-alpha profiles resemble the H-alpha line profiles of evolved star ejecta, suggesting that the Ly-alpha emission originates from a low column density and similar outflow geometry. The weak C II absorption and presence of non-resonant C II* emission in these GPs support this interpretation and imply a low LyC optical depth along the line of sight. In two additional GPs, weak Ly-alpha emission and strong C II absorption suggest a higher optical depth. These two GPs differ in their Ly-alpha profile shapes and C II* emission strengths, ho...

  4. Assembling the CMS yoke end-caps

    CERN Multimedia

    Laurent Guiraud

    2001-01-01

    A crane is used to piece together one of the end-caps that will provide the path for magnetic flux return on the CMS experiment. A total of six end-cap discs will be assembled before being positioned on the barrel yoke to complete the huge 12 500 tonne cylinder yoke. The magnetic field produced will be greater than any other solenoid created to date at 4 T, 100 000 times greater than the Earth's natural magnetic field, and will store enough energy to melt 18 tonnes of gold.

  5. Pharmacy benefit caps and the chronically ill.

    Science.gov (United States)

    Joyce, Geoffrey F; Goldman, Dana P; Karaca-Mandic, Pinar; Zheng, Yuhui

    2007-01-01

    In this paper we examine medication use among retirees with employer-sponsored drug coverage both with and without annual benefit limits. We find that pharmacy benefit caps are associated with higher rates of medication discontinuation across the most common therapeutic classes and that only a minority of those who discontinue use reinitiate therapy once coverage resumes. Plan members who reach their cap are more likely than others to switch plans and increase their rate of generic use; however, in most cases, the shift is temporary. Given the similarities between these plans and Part D, we make some inferences about reforms for Medicare.

  6. Design and implementation of the CAPS receiver

    Institute of Scientific and Technical Information of China (English)

    HU YongHui; HUA Yu; HOU Lei; WEI JingFa; WU JianFeng

    2009-01-01

    In this paper,baaed on analyses of the Chinese Area Positioning System (CAPS) satellite (GEO satellite) resources and signal properties,the signal power at the port of the receiver antenna is estimated,and the implementation projects are presented for a switching band C to band L CAPS C/A code receiver integrated with GPS receiver suite and for a CAPS dual frequency P code receiver.A microstrip receiving antenna is designed with high sensitivity and wide beam orientation,the RF front end of the C/A code and P code receivers,and a processor is designed for the navigation baseband.A single frequency CAPS C/A code receiver and a CAPS dual frequency P code receiver are built at the same time.A software process flow is provided,and research on relatively key techniques is also conducted,such as signal searching,code loop and carrier loop algorithms,a height assistant algorithm,a dual frequency difference speed measurement technique,a speed measurement technique using a single frequency source with frequency assistance,and a CAPS time correcting algorithm,according to the design frame of the receiver hardware.Research results show that the static plane positioning accuracy of the CAPS C/A code receiver is 20.5-24.6 m,height accuracy is 1.2-12.8 m,speed measurement accuracy is 0.13-0.3 m/s,dynamic plane positioning accuracy is 24.4 m,height accuracy is 3.0 m,and speed measurement accuracy is 0.24 m/s.In the case of C/A code,the timing accuracy is 200 ha,and it is also shown that the positioning accuracy of the CAPS precise code receiver (1σ) is 5 m from south to north,and 0.8 m from east to west.Finally,research on positioning accuracy is also conducted.

  7. QED-PIC simulations of electromagnetic cascades at the surface of pulsar's polar cap

    Science.gov (United States)

    Grismayer, Thomas; Vranic, Marija; Fonseca, Ricardo; Silva, Luis

    2016-10-01

    The recent implementation of the QED module in the OSIRIS 3.0 framework has enabled to simulate various scenarios where pair production or gamma-rays emission can be produced with ultra-intense lasers and/or relativistic particles beams. In this study we leverage on these numerical tools to study extreme astrophysical scenarios where self-consistent produced electron-positron pair plasmas are of relevance such as in pulsar magnetospheres. The dynamics of pulsar's polar cap cascade, based on the Ruderman-Sutherland model, has been investigated for the first time numerically in one dimension by Timokhin. Including quantum synchrotron radiation additionally to curvature photon radiation for the possible processes responsible for photon emission, we present the results of one and two dimensional QED-PIC simulations of the development of electromagnetic cascades at the surface of the polar cap and the subsequent plasma discharges that are accompanied by strong electrostatic waves.

  8. Interferon-alpha caused reversible parkinsonism.

    Science.gov (United States)

    Lu, Chieh-Sheng; Kao, Wei-Yau; Lin, Jiann-Chyun; Chang, Ping-Ying

    2015-01-01

    Interferon has been used to treat chronic viral hepatitis and several malignancies. However, it may cause various neuropsychiatric adverse effects including parkinsonism. We report a rare case of interferon alpha-2a therapy-related parkinsonism in a 67-year-old man with metastatic papillary renal cell carcinoma and our experience of using Tc-99m-TRODAT-1 single photon emission computed tomography (SPECT) as a tool for evaluation of parkinsonism. Physicians should be alert to the possibility of interferon alpha-2a-related parkinsonism.

  9. New ALPHA-2 magnet

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    On 21 June, members of the ALPHA collaboration celebrated the handover of the first solenoid designed for the ALPHA-2 experiment. The magnet has since been successfully installed and is working well.   Khalid Mansoor, Sumera Yamin and Jeffrey Hangst in front of the new ALPHA-2 solenoid. “This was the first of three identical solenoids that will be installed between now and September, as the rest of the ALPHA-2 device is installed and commissioned,” explains ALPHA spokesperson Jeffrey Hangst. “These magnets are designed to allow us to transfer particles - antiprotons, electrons and positrons - between various parts of the new ALPHA-2 device by controlling the transverse size of the particle bunch that is being transferred.” Sumera Yamin and Khalid Mansoor, two Pakistani scientists from the National Centre for Physics in Islamabad, came to CERN in February specifically to design and manufacture these magnets. “We had the chance to work on act...

  10. Lyman Alpha Control

    CERN Document Server

    Nielsen, Daniel Stefaniak

    2015-01-01

    This document gives an overview of how to operate the Lyman Alpha Control application written in LabVIEW along with things to watch out for. Overview of the LabVIEW code itself as well as the physical wiring of and connections from/to the NI PCI-6229 DAQ box is also included. The Lyman Alpha Control application is the interface between the ALPHA sequencer and the HighFinesse Wavelength Meter as well as the Lyman Alpha laser setup. The application measures the wavelength of the output light from the Lyman Alpha cavity through the Wavelength Meter. The application can use the Wavelength Meter’s PID capabilities to stabilize the Lyman Alpha laser output as well as switch between up to three frequencies.

  11. SNP2CAPS: a SNP and INDEL analysis tool for CAPS marker development

    OpenAIRE

    Thiel, Thomas; Kota, Raja; Grosse, Ivo; Stein, Nils; Graner, Andreas

    2004-01-01

    With the influx of various SNP genotyping assays in recent years, there has been a need for an assay that is robust, yet cost effective, and could be performed using standard gel-based procedures. In this context, CAPS markers have been shown to meet these criteria. However, converting SNPs to CAPS markers can be a difficult process if done manually. In order to address this problem, we describe a computer program, SNP2CAPS, that facilitates the computational conversion of SNP markers into CA...

  12. Interpreting EEG alpha activity.

    Science.gov (United States)

    Bazanova, O M; Vernon, D

    2014-07-01

    Exploring EEG alpha oscillations has generated considerable interest, in particular with regards to the role they play in cognitive, psychomotor, psycho-emotional and physiological aspects of human life. However, there is no clearly agreed upon definition of what constitutes 'alpha activity' or which of the many indices should be used to characterize it. To address these issues this review attempts to delineate EEG alpha-activity, its physical, molecular and morphological nature, and examine the following indices: (1) the individual alpha peak frequency; (2) activation magnitude, as measured by alpha amplitude suppression across the individual alpha bandwidth in response to eyes opening, and (3) alpha "auto-rhythmicity" indices: which include intra-spindle amplitude variability, spindle length and steepness. Throughout, the article offers a number of suggestions regarding the mechanism(s) of alpha activity related to inter and intra-individual variability. In addition, it provides some insights into the various psychophysiological indices of alpha activity and highlights their role in optimal functioning and behavior.

  13. Alpha Shapes and Proteins

    DEFF Research Database (Denmark)

    Winter, Pawel; Sterner, Henrik; Sterner, Peter

    2009-01-01

    We provide a unified description of (weighted) alpha shapes, beta shapes and the corresponding simplicialcomplexes. We discuss their applicability to various protein-related problems. We also discuss filtrations of alpha shapes and touch upon related persistence issues.We claim that the full...... potential of alpha-shapes and related geometrical constructs in protein-related problems yet remains to be realized and verified. We suggest parallel algorithms for (weighted) alpha shapes, and we argue that future use of filtrations and kinetic variants for larger proteins will need such implementation....

  14. Knowledge Management at Cap Gemini Nederland

    NARCIS (Netherlands)

    M.J. Vlaanderen (Marie Jose)

    1998-01-01

    textabstractThe theme of this paper is knowledge management (KM) at an organization that provides information technology (IT) services. It is based on the results of a KM-survey of the Finance Division of Cap Gemini (CG) conducted during the spring of 1997.

  15. Mapping of p140Cap phosphorylation sites

    DEFF Research Database (Denmark)

    Repetto, Daniele; Aramu, Simona; Boeri Erba, Elisabetta;

    2013-01-01

    Protein phosphorylation tightly regulates specific binding of effector proteins that control many diverse biological functions of cells (e. g. signaling, migration and proliferation). p140Cap is an adaptor protein, specifically expressed in brain, testis and epithelial cells, that undergoes phosp...

  16. The Effectiveness of Caps on Political Lobbying

    NARCIS (Netherlands)

    Matejka, M.; Onderstal, A.M.; De Waegenaere, A.M.B.

    2002-01-01

    In this paper, we analyze a lobby game, modelled as an all-pay auction in which interest groups submit bids in order to obtain a political prize.The bids are restricted to be below a cap imposed by the government.For both an incomplete and a complete information setting we show the following results

  17. CAP Reform and the Doha Development Agenda

    NARCIS (Netherlands)

    van Dijck, P.; Faber, G.

    2004-01-01

    The CAP reforms that the EU accepted in June 2003 will partially decouple direct income payments to farmers from production and make these payments conditional on cross-compliance. The reforms are driven by enlargement of EU membership, budgetary constraints, mounting pressures from diverse animal w

  18. ATLAS: End-cap Toroid assembly

    CERN Multimedia

    2006-01-01

    In building 191 and building 180- assembly of this massive piece.To reach the top of the end-cap the cranes has to be used and during the assembly you can see welding and hear many tools running background.

  19. Structure, stability and folding of the alpha-helix.

    Science.gov (United States)

    Doig, A J; Andrew, C D; Cochran, D A; Hughes, E; Penel, S; Sun, J K; Stapley, B J; Clarke, D T; Jones, G R

    2001-01-01

    Pauling first described the alpha-helix nearly 50 years ago, yet new features of its structure continue to be discovered, using peptide model systems, site-directed mutagenesis, advances in theory, the expansion of the Protein Data Bank and new experimental techniques. Helical peptides in solution form a vast number of structures, including fully helical, fully coiled and partly helical. To interpret peptide results quantitatively it is essential to use a helix/coil model that includes the stabilities of all these conformations. Our models now include terms for helix interiors, capping, side-chain interactions, N-termini and 3(10)-helices. The first three amino acids in a helix (N1, N2 and N3) and the preceding N-cap are unique, as their amide NH groups do not participate in backbone hydrogen bonding. We surveyed their structures in proteins and measured their amino acid preferences. The results are predominantly rationalized by hydrogen bonding to the free NH groups. Stabilizing side-chain-side-chain energies, including hydrophobic interactions, hydrogen bonding and polar/non-polar interactions, were measured accurately in helical peptides. Helices in proteins show a preference for having approximately an integral number of turns so that their N- and C-caps lie on the same side. There are also strong periodic trends in the likelihood of terminating a helix with a Schellman or alpha L C-cap motif. The kinetics of alpha-helix folding have been studied with stopped-flow deep ultraviolet circular dichroism using synchrotron radiation as the light source; this gives a far superior signal-to-noise ratio than a conventional instrument. We find that poly(Glu), poly(Lys) and alanine-based peptides fold in milliseconds, with longer peptides showing a transient overshoot in helix content.

  20. Alpha decay potential barriers and half-lives and analytical formula predictions for superheavy nuclei

    OpenAIRE

    Royer, G.; Zhang, H. F.

    2008-01-01

    International audience; The synthesis of superheavy elements has advanced strongly recently and their main observed decay mode is alpha emission. Predictions of alpha decay half-lives of other possible superheavy nuclei are needed. The alpha decay potential barrier is often described using a finite square well for the one-body shapes plus an hyperbola for the Coulomb repulsion between the alpha particle and its daughter. An arbitrary adjustment of the parameters allows to reproduce roughly th...

  1. CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.

    Science.gov (United States)

    Jockusch, Wolf J; Speidel, Dina; Sigler, Albrecht; Sørensen, Jakob B; Varoqueaux, Frederique; Rhee, Jeong-Seop; Brose, Nils

    2007-11-16

    Before transmitter-filled synaptic vesicles can fuse with the plasma membrane upon stimulation they have to be primed to fusion competence. The regulation of this priming process controls the strength and plasticity of synaptic transmission between neurons, which in turn determines many complex brain functions. We show that CAPS-1 and CAPS-2 are essential components of the synaptic vesicle priming machinery. CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, which causes a selective impairment of fast phasic transmitter release. Increases in the intracellular Ca(2+) levels can transiently revert this defect. Our findings demonstrate that CAPS proteins generate and maintain a highly fusion competent synaptic vesicle pool that supports phasic Ca(2+) triggered release of transmitters.

  2. The HADES RV Programme with HARPS-N@TNG IV. Time resolved analysis of the Ca ii H&K and H{\\alpha} chromospheric emission of low-activity early-type M dwarfs

    CERN Document Server

    Scandariato, G; Biazzo, K; Leto, G; Stelzer, B; Sanchez, R Zanmar; Claudi, R; Cosentino, R; Damasso, M; Desidera, S; Álvarez, E González; Hernández, J I González; Gratton, R; Lanza, A F; Maggio, A; Messina, S; Micela, G; Pagano, I; Perger, M; Piotto, G; Rebolo, R; Ribas, I; Rosich, A; Sozzetti, A; Mascareño, A Suárez

    2016-01-01

    M dwarfs are prime targets for planet search programs, particularly of those focused on the detection and characterization of rocky planets in the habitable zone. Understanding their magnetic activity is important because it affects our ability to detect small planets, and it plays a key role in the characterization of the stellar environment. We analyze observations of the Ca II H&K and H{\\alpha} lines as diagnostics of chromospheric activity for low-activity early-type M dwarfs. We analyze the time series of spectra of 71 early-type M dwarfs collected for the HADES project for planet search purposes. The HARPS-N spectra provide simultaneously the H&K doublet and the H{\\alpha} line. We develop a reduction scheme able to correct the HARPS-N spectra for instrumental and atmospheric effects, and to provide flux-calibrated spectra in units of flux at the stellar surface. The H&K and H{\\alpha} fluxes are compared with each other, and their variability is analyzed. We find that the H and K flux excesse...

  3. 'Cooling Caps' May Halt Chemo-Linked Hair Loss

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_163580.html 'Cooling Caps' May Halt Chemo-Linked Hair Loss One ... 2017 TUESDAY, Feb. 14, 2017 (HealthDay News) -- Scalp cooling caps can help breast cancer patients save their ...

  4. Facially amphiphilic thiol capped gold and silver nanoparticles

    Indian Academy of Sciences (India)

    Shreedhar Bhata; Uday Maitra

    2008-11-01

    A series of bile acid-derived facially amphiphilic thiols have been used to cap sliver and gold nanoparticles. The self-assembling properties of these steroid-capped nanoparticles have been investigated and reported in this article.

  5. Buffett’s Alpha

    DEFF Research Database (Denmark)

    Frazzini, Andrea; Kabiller, David; Heje Pedersen, Lasse

    Berkshire Hathaway has realized a Sharpe ratio of 0.76, higher than any other stock or mutual fund with a history of more than 30 years, and Berkshire has a significant alpha to traditional risk factors. However, we find that the alpha becomes insignificant when controlling for exposures to Betting...

  6. Fabrication of macroporous carbonate apatite foam by hydrothermal conversion of alpha-tricalcium phosphate in carbonate solutions.

    Science.gov (United States)

    Wakae, H; Takeuchi, A; Udoh, K; Matsuya, S; Munar, M L; LeGeros, R Z; Nakasima, A; Ishikawa, K

    2008-12-15

    Bone consists of a mineral phase (carbonate apatite) and an organic phase (principally collagen). Cancellous bone is characterized by interconnecting porosity necessary for tissue ingrowth and nourishment of bone cells. The purpose of the present study was to fabricate macroporous carbonate apatite (CAP) blocks with interconnecting porosity as potential bone substitute biomaterials by hydrothermal conversion of alpha-TCP foam in carbonate solution. The fabrication of the macroporous CAP was accomplished in two steps: (1) preparation of alpha-TCP foams using polyurethane foams as templates, and (2) hydrothermal conversion at 200 degrees C of alpha-TCP foam in the presence of ammonium carbonate solutions of different concentrations. The maximum carbonate content of the resultant CAP foam was approximately 7.4 wt %. The mean porosity of the CAP foam was as high as 93 vol %. The macroporous CAP blocks or granules prepared in this manner has properties similar to that of bone in mineral composition and in having interconnecting macroporosity necessary for osteoconductivity and tissue ingrowth. On the basis of composition and interconnecting macroporosity, the CAP foam materials could be ideal biomaterials for bone repair and as scaffolds for tissue engineering.

  7. Scattered H-alpha light from Galactic dust clouds

    CERN Document Server

    Mattila, K; Lehtinen, K

    2006-01-01

    Bright emission nebulae, or HII regions, around hot stars are readily seen in H-alpha light. However, the all-pervasive faint H-alpha emission has only recently been detected and mapped over the whole sky. Mostly the H-alpha emission observed along a line of sight is produced by ionised gas in situ. There are, however, cases where all or most of the H-alpha radiation is due to scattering by electrons or dust particles which are illuminated by an H-alpha emitting source off the line of sight. Here we demonstrate that diffuse, translucent and dark dust clouds at high galactic latitudes are in many cases observed to have an excess of diffuse H-alpha surface brightness, i.e. they are brighter than the surrounding sky. We show that the majority of this excess surface brightness can be understood as light scattered off the interstellar dust grains. The source of incident photons is the general Galactic H-alpha background radiation impinging on the dust clouds from all over the sky.

  8. A new method of ionospheric-free hybrid differential positioning based on a double-antenna CAPS receiver

    Institute of Scientific and Technical Information of China (English)

    GUO JinYun; HAN YanBen; CHANG XiaoTao

    2009-01-01

    Chinese Area Positioning System (CAPS) is a transmitted satellite navigation system moved by the Chinese Academy of Sciences.Three basic modes of navigation and positioning with CAPS are given,and then a comparative analysis is made in this paper.In terms of the principle that the ionospheric delay is at an inverse ratio to the frequency square,a new ionospheric-free positioning method based on a double-antenna CAPS receiver is put forward.Then the hybrid differential observations and the solving equations and algorithms for one epoch and multi epochs are deduced according to the basic principle of the method.The method may remove the global errors in signal emission,propagation,transmission and receiving (e.g.,ionospheric delay,hardware delay,and clock error).So it is very convenient for the single-epoch solution and multi-epoch navigation and positioning,and may efficiently improve the precision of real time CAPS navigation.Furthermore,the method can be used not only for the geometric orbit determination of CAPS GEO and IGSO satellites and the navigation and positioning,but also for the estimation of the tropospheric zenith delay,which is useful for the study of water vapor changes in the atmosphere.Polynomials are used in this method to express the tropospheric zenith delay and CAPS satellite orbits within the limited time interval,which reduces the number of unknown parameters and thus speeds the computation.

  9. A new method of ionospheric-free hybrid differential positioning based on a double-antenna CAPS receiver

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Chinese Area Positioning System (CAPS) is a transmitted satellite navigation system moved by the Chinese Academy of Sciences. Three basic modes of navigation and positioning with CAPS are given, and then a comparative analysis is made in this paper. In terms of the principle that the ionospheric delay is at an inverse ratio to the frequency square, a new ionospheric-free positioning method based on a double-antenna CAPS receiver is put forward. Then the hybrid differential observations and the solving equations and algorithms for one epoch and multi epochs are deduced according to the basic principle of the method. The method may remove the global errors in signal emission, propagation, transmission and receiving (e.g., ionospheric delay, hardware delay, and clock error). So it is very convenient for the single-epoch solution and multi-epoch navigation and positioning, and may efficiently improve the precision of real time CAPS navigation. Furthermore, the method can be used not only for the geometric orbit determination of CAPS GEO and IGSO satellites and the navigation and positioning, but also for the estimation of the tropospheric zenith delay, which is useful for the study of water vapor changes in the atmosphere. Polynomials are used in this method to express the tropospheric zenith delay and CAPS satellite orbits within the limited time interval, which reduces the num- ber of unknown parameters and thus speeds the computation.

  10. CMS end-cap yoke at the detector's assembly site.

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    The magnetic flux generated by the superconducting coil in the CMS detector is returned via an iron yoke comprising three end-cap discs at each end (end-cap yoke) and five concentric cylinders (barrel yoke). This picture shows the first of three end-cap discs (red) seen through the outer cylinder of the vacuum tank which will house the superconducting coil.

  11. Studying Lyman-alpha escape and reionization in Green Pea galaxies

    Science.gov (United States)

    Yang, Huan; Malhotra, Sangeeta; Rhoads, James E.; Gronke, Max; Leitherer, Claus; Wofford, Aida; Dijkstra, Mark

    2017-01-01

    Green Pea galaxies are low-redshift galaxies with extreme [OIII]5007 emission line. We built the first statistical sample of Green Peas observed by HST/COS and used them as analogs of high-z Lyman-alpha emitters to study Ly-alpha escape and Ly-alpha sizes. Using the HST/COS 2D spectra, we found that Ly-alpha sizes of Green Peas are larger than the UV continuum sizes. We found many correlations between Ly-alpha escape fraction and galactic properties -- dust extinction, Ly-alpha kinematic features, [OIII]/[OII] ratio, and gas outflow velocities. We fit an empirical relation to predict Ly-alpha escape fraction from dust extinction and Ly-alpha red-peak velocity. In the JWST era, we can use this relation to derive the IGM HI column density along the line of sight of each high-z Ly-alpha emitter and probe the reionization process.

  12. Lyman-alpha observations of astrospheres

    CERN Document Server

    Linsky, Jeffrey L

    2014-01-01

    Charge-exchange reactions between outflowing stellar wind protons and interstellar neutral hydrogen atoms entering a stellar astrosphere produce a region of piled-up-decelerated neutral hydrogen called the hydrogen wall. Absorption by this gas, which is observed in stellar Lyman-alpha emission lines, provides the only viable technique at this time for measuring the mass-loss rates of F-M dwarf stars. We describe this technique, present an alternative way for understanding the relation of mass-loss rate with X-ray emission, and identify several critical issues.

  13. Genetics Home Reference: alpha thalassemia

    Science.gov (United States)

    ... Understand Genetics Home Health Conditions alpha thalassemia alpha thalassemia Enable Javascript to view the expand/collapse boxes. Download PDF Open All Close All Description Alpha thalassemia is a blood disorder that reduces the production ...

  14. Results and Outlook of The Aluminum Capture Experiment (AlCap)

    Science.gov (United States)

    Quirk, John R.; Miller, James; ALCap Collaboration Collaboration

    2016-03-01

    Observation of neutrinoless muon-to-electron conversion in the presence of a nucleus would be unambiguous evidence of physics Beyond the Standard Model. Two experiments, COMET at J-PARC and Mu2e at Fermilab, will search for this process in the coming decade. Barring discovery, these experiments will provide upper-limits on this branching ratio up to 10,000 times better than previously published. COMET/Mu2e developed a joint venture, the AlCap Experiment, to measure particle emission spectra from muonic interactions in a number of materials. As a major source of background hits in COMET/Mu2e detectors, AlCap sought to measure the charged particle and neutron spectra following nuclear capture on the candidate target materials aluminum and titanium. Additionally, COMET/Mu2e are exploring normalization schemes via AlCap's measurement of the photon spectra following both atomic and nuclear capture. Over the course of 2013 and 2015, AlCap performed three runs at the Paul Scherrer Institut in Switzerland. The first acquired preliminary data for all spectra, the second run collected only neutron and photon data, and the third primarily charged particle data. Preliminary analyses of the first two runs, already impactful for COMET/Mu2e, is presented along with a summary of the third.

  15. Sublimation and transport of water from the north residual polar cap on Mars

    Science.gov (United States)

    Haberle, Robert M.; Jakosky, Bruce M.

    1990-01-01

    The possible role of the north residual cap in the current Martian water cycle was examined using models to assess the ability of the cap to supply water to the atmosphere and the ability of the atmospheric circulation to transport it out of the polar regions to low northern latitudes. Results indicate that rather extreme circumstances would be required for the cap to provide all of the observed increase in atmospheric water, such as a combination of high surface winds, low cap emissivities, or substantial evaporation from dark material. But even if these conditions could be met, the high-latitude circulation is too localized in scale to move much water vapor out of the polar environment. Both the present calculations and the data from the Viking's Mars Atmospheric Water Detection Experiment show that about two thirds of the water appearing in the Martian northern hemisphere during summer must be supplied by other sources. It is suggested that the additional source is water desorbing from the nonpolar regolith.

  16. Electronic Structures of S-Doped Capped C-SWNT from First Principles Study.

    Science.gov (United States)

    Wang, L; Zhang, Yz; Zhang, Yf; Chen, Xs; Lu, W

    2010-04-14

    The semiconducting single-walled carbon nanotube (C-SWNT) has been synthesized by S-doping, and they have extensive potential application in electronic devices. We investigated the electronic structures of S-doped capped (5, 5) C-SWNT with different doping position using first principles calculations. It is found that the electronic structures influence strongly on the workfunction without and with external electric field. It is considered that the extended wave functions at the sidewall of the tube favor for the emission properties. With the S-doping into the C-SWNT, the HOMO and LUMO charges distribution is mainly more localized at the sidewall of the tube and the presence of the unsaturated dangling bond, which are believed to enhance workfunction. When external electric field is applied, the coupled states with mixture of localized and extended states are presented at the cap, which provide the lower workfunction. In addition, the wave functions close to the cap have flowed to the cap as coupled states and to the sidewall of the tube mainly as extended states, which results in the larger workfunction. It is concluded that the S-doped C-SWNT is not incentive to be applied in field emitter fabrication. The results are also helpful to understand and interpret the application in other electronic devices.

  17. Electronic Structures of S-Doped Capped C-SWNT from First Principles Study

    Directory of Open Access Journals (Sweden)

    Chen XS

    2010-01-01

    Full Text Available Abstract The semiconducting single-walled carbon nanotube (C-SWNT has been synthesized by S-doping, and they have extensive potential application in electronic devices. We investigated the electronic structures of S-doped capped (5, 5 C-SWNT with different doping position using first principles calculations. It is found that the electronic structures influence strongly on the workfunction without and with external electric field. It is considered that the extended wave functions at the sidewall of the tube favor for the emission properties. With the S-doping into the C-SWNT, the HOMO and LUMO charges distribution is mainly more localized at the sidewall of the tube and the presence of the unsaturated dangling bond, which are believed to enhance workfunction. When external electric field is applied, the coupled states with mixture of localized and extended states are presented at the cap, which provide the lower workfunction. In addition, the wave functions close to the cap have flowed to the cap as coupled states and to the sidewall of the tube mainly as extended states, which results in the larger workfunction. It is concluded that the S-doped C-SWNT is not incentive to be applied in field emitter fabrication. The results are also helpful to understand and interpret the application in other electronic devices.

  18. Should we geoengineer larger ice caps?

    CERN Document Server

    Haqq-Misra, Jacob

    2015-01-01

    The climate of Earth is susceptible to catastrophes that could threaten the longevity of human civilization. Geoengineering to reduce incoming solar radiation has been suggested as a way to mediate the warming effects of contemporary climate change, but a geoengineering program for thousands of years could also be used to enlarge the size of the polar ice caps and create a permanently cooler climate. Such a large ice cap state would make Earth less susceptible to climate threats and could allow human civilization to survive further into the future than otherwise possible. Intentionally extending Earth's glacial coverage will require uninterrupted commitment to this program for millenia but would ultimately reach a cooler equilibrium state where geoengineering is no longer needed. Whether or not this program is ever attempted, this concept illustrates the need to identify preference among potential climate states to ensure the long-term success of civilization.

  19. Status of the AlCap experiment

    CERN Document Server

    Litchfield, R Phillip

    2015-01-01

    The AlCap experiment is a joint project between the COMET and Mu2e collaborations. Both experiments intend to look for the lepton-flavour violating conversion $\\mu + A \\rightarrow e + A$, using tertiary muons from high-power pulsed proton beams. In these experiments the products of ordinary muon capture in the muon stopping target are an important concern, both in terms of hit rates in tracking detectors and radiation damage to equipment. The goal of the AlCap experiment is to provide precision measurements of the products of nuclear capture on Aluminium, which is the favoured target material for both COMET and Mu2e. The results will be used for optimising the design of both conversion experiments, and as input to their simulations. Data was taken in December 2013 and is currently being analysed.

  20. Greening CAP payments: a missed opportunity?

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, Alan

    2013-01-15

    At an important point in the current reform of the Common Agricultural Policy (CAP), a new IIEA policy brief by Professor Alan Matthews, one of the EU’s foremost experts on the topic, considers proposals to green direct farm payments. Professor Matthews argues that proposed greening of direct payments – the key innovation in the current round of CAP Reform – look likely to fail. While greening may survive as a concept, the likely outcome of the negotiations between Agriculture Ministers and the European Parliament will deliver little practical environmental benefit. The paper examines the rationale underpinning greening, arguing that it exists to justify the continuation of a large agricultural budget, explores reasons for the apparent failure of the proposals, and reflects on the implications for future efforts to better integrate environmental objectives into EU agriculture policy. This is the first in a series of Environment Nexus policy briefs by leading experts in the fields of agriculture, energy, climate change and water.

  1. Cytocompatibility and Antibacterial Properties of Capping Materials

    OpenAIRE

    Claudio Poggio; Carla Renata Arciola; Riccardo Beltrami; Annachiara Monaco; Alberto Dagna; Marco Lombardini; Livia Visai

    2014-01-01

    The aim of this study was to evaluate and compare the antimicrobial activity and cytocompatibility of six different pulp-capping materials: Dycal (Dentsply), Calcicur (Voco), Calcimol LC (Voco), TheraCal LC (Bisco), MTA Angelus (Angelus), and Biodentine (Septodont). To evaluate antimicrobial activity, materials were challenged in vitro with Streptococcus mutans, Streptococcus salivarius, and Streptococcus sanguis in the agar disc diffusion test. Cytocompatibility of the assayed materials towa...

  2. Farmer preference for CAPS: Workshop and analysis

    OpenAIRE

    Reed, B.F.

    2012-01-01

    Analytic Hierarchy Process (AHP) is a a multi-criteria, multi-level decision-making method which breaks down complex decisions into a series of simple questions reflecting an optimal goal, objectives, and various options. This provides a structured technique for organizing and analyzing differing preferences for Conservation Agriculture Production Systems (CAPS). This presentation explains AHP and conducts a survey to collect gender-specific preference data for selected conservation agricultu...

  3. Protein synthesis in geostimulated root caps

    Science.gov (United States)

    Feldman, L. J.

    1982-01-01

    A study is presented of the processes occurring in the root cap of corn which are requisite for the formation of root cap inhibitor and which can be triggered or modulated by both light and gravity. The results of this study indicate the importance of protein synthesis for light-induced gravitropic bending in roots. Root caps in which protein synthesis is prevented are unable to induce downward bending. This suggests that light acts by stimulating proteins which are necessary for the translation of the gravitropic stimulus into a growth response (downward bending). The turnover of protein with time was also examined in order to determine whether light acts by stimulating the synthesis of unique proteins required for downward growth. It is found that auxin in combination with light allows for the translation of the gravitropic stimulus into a growth response at least in part through the modification of protein synthesis. It is concluded that unique proteins are stimulated by light and are involved in promoting the downward growth in roots which are responding to gravity.

  4. Pulp-Capping with Mineral Trioxide Aggregate

    Directory of Open Access Journals (Sweden)

    Peycheva Kalina

    2015-11-01

    Full Text Available There are two considerations for direct pulp capping - accidental mechanical pulp exposure and exposure caused by caries. Mineral trioxide aggregate (MTA was used as pulp-capping material to preserve the vitality of the pulpal tissues. Follow-up examinations revealed that treatment was successful in preserving pulpal vitality and continued development of the tooth. On the basis of available information, it appears that MTA is the material of choice for some clinical applications. Material and methods: Cases 18 - 8 teeth with grey MTA, 10 teeth with white MTA; diagnose: Pulpitis chronica ulcerosa, Electro pulpal test (EOD - 30-35 μA, pre-clinical X-ray - without changes in the structures, follow ups for 4 years. Successful treatments: without clinical symptoms and changes in the X-rays: 5 teeth with grey MTA, 8 teeth with white MTA for period of 4 years. Unsuccessful treatments: Clinical symptoms and sometimes changes in the X-ray: 3 with grey MTA, 2 with white MTA. MTA is an appropriate material for pulp-capping and follow-up examinations revealed that the treatment was successful in preserving pulpal vitality.

  5. Diagnostic criteria for cryopyrin-associated periodic syndrome (CAPS).

    Science.gov (United States)

    Kuemmerle-Deschner, Jasmin B; Ozen, Seza; Tyrrell, Pascal N; Kone-Paut, Isabelle; Goldbach-Mansky, Raphaela; Lachmann, Helen; Blank, Norbert; Hoffman, Hal M; Weissbarth-Riedel, Elisabeth; Hugle, Boris; Kallinich, Tilmann; Gattorno, Marco; Gul, Ahmet; Ter Haar, Nienke; Oswald, Marlen; Dedeoglu, Fatma; Cantarini, Luca; Benseler, Susanne M

    2016-10-04

    Cryopyrin-associated periodic syndrome (CAPS) is a rare, heterogeneous disease entity associated with NLRP3 gene mutations and increased interleukin-1 (IL-1) secretion. Early diagnosis and rapid initiation of IL-1 inhibition prevent organ damage. The aim of the study was to develop and validate diagnostic criteria for CAPS. An innovative process was followed including interdisciplinary team building, item generation: review of CAPS registries, systematic literature review, expert surveys, consensus conferences for item refinement, item reduction and weighting using 1000Minds decision software. Resulting CAPS criteria were tested in large cohorts of CAPS cases and controls using correspondence analysis. Diagnostic models were explored using sensitivity analyses. The international team included 16 experts. Systematic literature and registry review identified 33 CAPS-typical items; the consensus conferences reduced these to 14. 1000Minds exercises ranked variables based on importance for the diagnosis. Correspondence analysis determined variables consistently associated with the diagnosis of CAPS using 284 cases and 837 controls. Seven variables were significantly associated with CAPS (pCAPS-typical symptoms: urticaria-like rash, cold-triggered episodes, sensorineural hearing loss, musculoskeletal symptoms, chronic aseptic meningitis and skeletal abnormalities. Sensitivity was 81%, specificity 94%. It performed well for all CAPS subtypes and regardless of NLRP3 mutation. The novel approach integrated traditional methods of evidence synthesis with expert consensus, web-based decision tools and innovative statistical methods and may serve as model for other rare diseases. These criteria will enable a rapid diagnosis for children and adults with CAPS.

  6. alpha_s from tau decays revisited

    CERN Document Server

    Boito, D; Golterman, M; Jamin, M; Maltman, K; Osborne, J; Peris, S

    2011-01-01

    Being a determination at low energies, the analysis of hadronic tau decay data provides a rather precise determination of the strong coupling alpha_s after evolving the result to M_Z. At such a level of precision, even small non-perturbative effects become relevant for the central value and error. While those effects had been taken into account in the framework of the operator product expansion, contributions going beyond it, so-called duality violations, have previously been neglected. The following investigation fills this gap through a finite-energy sum rule analysis of tau decay spectra from the OPAL experiment, including duality violations and performing a consistent fit of all appearing QCD parameters. The resulting values for alpha_s(M_tau) are 0.307(19) in fixed-order perturbation theory and 0.322(26) in contour-improved perturbation theory, which translates to the n_f=5 values 0.1169(25) and 0.1187(32) at M_Z, respectively.

  7. Scintillation and irregularities from the nightside part of a Sun-aligned polar cap arc

    Science.gov (United States)

    Meeren, Christer; Oksavik, Kjellmar; Lorentzen, Dag A.; Paxton, Larry J.; Clausen, Lasse B. N.

    2016-06-01

    In this paper we study the presence of irregularities and scintillation in relation to the nightside part of a long-lived, Sun-aligned transpolar arc on 15 January 2015. The arc was observed in DMSP UV and particle data and lasted at least 3 h between 1700 and 2000 UT. The arc was more intense than the main oval during this time. From all-sky imagers on Svalbard we were able to study the evolution of the arc, which drifted slowly westward toward the dusk cell. The intensity of the arc as observed from ground was 10-17 kR in 557.7 nm and 2-3.5 kR in 630.0 nm, i.e., significant emissions in both green and red emission lines. We have used high-resolution raw data from global navigation satellite systems (GNSS) receivers and backscatter from Super Dual Auroral Radar Network (SuperDARN) radars to study irregularities and scintillation in relation to the polar cap arc. Even though the literature has suggested that polar cap arcs are potential sources for irregularities, our results indicate only very weak irregularities. This may be due to the background density in the northward IMF polar cap being too low for significant irregularities to be created.

  8. Cold atmospheric plasma (CAP) changes gene expression of key molecules of the wound healing machinery and improves wound healing in vitro and in vivo.

    Science.gov (United States)

    Arndt, Stephanie; Unger, Petra; Wacker, Eva; Shimizu, Tetsuji; Heinlin, Julia; Li, Yang-Fang; Thomas, Hubertus M; Morfill, Gregor E; Zimmermann, Julia L; Bosserhoff, Anja-Katrin; Karrer, Sigrid

    2013-01-01

    Cold atmospheric plasma (CAP) has the potential to interact with tissue or cells leading to fast, painless and efficient disinfection and furthermore has positive effects on wound healing and tissue regeneration. For clinical implementation it is necessary to examine how CAP improves wound healing and which molecular changes occur after the CAP treatment. In the present study we used the second generation MicroPlaSter ß® in analogy to the current clinical standard (2 min treatment time) in order to determine molecular changes induced by CAP using in vitro cell culture studies with human fibroblasts and an in vivo mouse skin wound healing model. Our in vitro analysis revealed that the CAP treatment induces the expression of important key genes crucial for the wound healing response like IL-6, IL-8, MCP-1, TGF-ß1, TGF-ß2, and promotes the production of collagen type I and alpha-SMA. Scratch wound healing assays showed improved cell migration, whereas cell proliferation analyzed by XTT method, and the apoptotic machinery analyzed by protein array technology, was not altered by CAP in dermal fibroblasts. An in vivo wound healing model confirmed that the CAP treatment affects above mentioned genes involved in wound healing, tissue injury and repair. Additionally, we observed that the CAP treatment improves wound healing in mice, no relevant side effects were detected. We suggest that improved wound healing might be due to the activation of a specified panel of cytokines and growth factors by CAP. In summary, our in vitro human and in vivo animal data suggest that the 2 min treatment with the MicroPlaSter ß® is an effective technique for activating wound healing relevant molecules in dermal fibroblasts leading to improved wound healing, whereas the mechanisms which contribute to these observed effects have to be further investigated.

  9. Cold atmospheric plasma (CAP changes gene expression of key molecules of the wound healing machinery and improves wound healing in vitro and in vivo.

    Directory of Open Access Journals (Sweden)

    Stephanie Arndt

    Full Text Available Cold atmospheric plasma (CAP has the potential to interact with tissue or cells leading to fast, painless and efficient disinfection and furthermore has positive effects on wound healing and tissue regeneration. For clinical implementation it is necessary to examine how CAP improves wound healing and which molecular changes occur after the CAP treatment. In the present study we used the second generation MicroPlaSter ß® in analogy to the current clinical standard (2 min treatment time in order to determine molecular changes induced by CAP using in vitro cell culture studies with human fibroblasts and an in vivo mouse skin wound healing model. Our in vitro analysis revealed that the CAP treatment induces the expression of important key genes crucial for the wound healing response like IL-6, IL-8, MCP-1, TGF-ß1, TGF-ß2, and promotes the production of collagen type I and alpha-SMA. Scratch wound healing assays showed improved cell migration, whereas cell proliferation analyzed by XTT method, and the apoptotic machinery analyzed by protein array technology, was not altered by CAP in dermal fibroblasts. An in vivo wound healing model confirmed that the CAP treatment affects above mentioned genes involved in wound healing, tissue injury and repair. Additionally, we observed that the CAP treatment improves wound healing in mice, no relevant side effects were detected. We suggest that improved wound healing might be due to the activation of a specified panel of cytokines and growth factors by CAP. In summary, our in vitro human and in vivo animal data suggest that the 2 min treatment with the MicroPlaSter ß® is an effective technique for activating wound healing relevant molecules in dermal fibroblasts leading to improved wound healing, whereas the mechanisms which contribute to these observed effects have to be further investigated.

  10. Alpha-1 Antitrypsin Deficiency

    Science.gov (United States)

    ... by blood tests showing the low levels of alpha-1 antitrypsin and abnormal liver tests. Other tests such as ultrasound imaging or tests using specialized X-ray techniques may be necessary. A liver biopsy may ...

  11. AlphaACT

    Science.gov (United States)

    2014-07-20

    CBR can be found in the world around us (e.g., a doctor’s diagnosis based on a prior patient case, a lawyer preparing arguments based on legal ... metaphors in decision research. Judgment & Decision Making, 3(3), 195-204. Payne, J., Bettman, J., & Johnson, E. (1993). The Adaptive Decision Maker...alphaact. com 64 AlphaACT HAZMAT User Guide 8.3 Changing Measurement Units AlphaACT HAZMAT lets you show distances in either metric or English

  12. ALPHA-2: the sequel

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    While many experiments are methodically planning for intense works over the long shutdown, there is one experiment that is already working at full steam: ALPHA-2. Its final components arrived last month and will completely replace the previous ALPHA set-up. Unlike its predecessor, this next generation experiment has been specifically designed to measure the properties of antimatter.   The ALPHA team lower the new superconducting solenoid magnet into place. The ALPHA collaboration is working at full speed to complete the ALPHA-2 set-up for mid-November – this will give them a few weeks of running before the AD shutdown on 17 December. “We really want to get some experience with this device this year so that, if we need to make any changes, we will have time during the long shutdown in which to make them,” says Jeffrey Hangst, ALPHA spokesperson. “Rather than starting the 2014 run in the commissioning stage, we will be up and running from the get go.&...

  13. Cross Sections for proton induced high energy $\\gamma$-ray emission (PIGE) in reaction $^{19}$F(p,$\\alpha\\gamma$)$^{16}$O at incident proton energies between 1.5 and 4 MeV

    CERN Document Server

    Cabanelas, P; Fonseca, M; Galaviz, D; Henriques, A; Jesus, A P; Luís, H; Sánchez-Benítez, A; Santos, C; Silva, H; Teubig, P; Velho, P

    2016-01-01

    We have studied the high energy gamma-rays produced in the reaction $^{19}$F(p,$\\alpha\\gamma$)$^{16}$O for incident proton energies from 1.5 to 4.0 MeV over NaF/Ag and CaF$_2$/Ag thin targets in two different sets of data. Gamma-rays were detected with a High Purity Ge detector with an angle of 130$^{o}$ with respect to the beam axis. The cross-sections for the high energy gamma-rays of 6.129, 6.915 and 7.115 MeV have been measured for the whole group between 5 and 7.2 MeV with accuracy better than 10%. A new energy range was covered and more points are included in the cross-sections data base. Results are in agreement with previous measurements in similar conditions.

  14. Studies on the chemical synthesis and characterization of lead oxide nanoparticles with different organic capping agents

    Energy Technology Data Exchange (ETDEWEB)

    Arulmozhi, K. T., E-mail: arulsheelphy@gmail.com [Physics Wing (DDE), Annamalai University, Tamil Nadu, India - 608 002 (India); Mythili, N. [Department of Physics, Annamalai University, Tamil Nadu, India - 608 002 (India)

    2013-12-15

    Lead oxide (PbO) nanoparticles were chemically synthesized using Lead (II) acetate as precursor. The effects of organic capping agents such as Oleic acid, Ethylene Diamine Tetra Acetic acid (EDTA) and Cetryl Tri Methyl Butoxide (CTAB) on the size and morphology of the nanoparticles were studied. Characterization techniques such as X-ray diffraction (XRD), Fourier Transform-Infrared spectroscopy (FT-IR), Photoluminescence (PL) Field Emission Scanning Electron Microscopy (FE-SEM), Energy Dispersive Spectroscopy (EDS) and Transmission Electron Microscopy (TEM) were used to analyse the prepared nanoparticles for their physical, structural and optical properties. The characterization studies reveal that the synthesized PbO nanoparticles had well defined crystalline structure and sizes in the range of 25 nm to 36 nm for capping agents used and 40 nm for pure PbO nanoparticles.

  15. Studies on the chemical synthesis and characterization of lead oxide nanoparticles with different organic capping agents

    Directory of Open Access Journals (Sweden)

    K. T. Arulmozhi

    2013-12-01

    Full Text Available Lead oxide (PbO nanoparticles were chemically synthesized using Lead (II acetate as precursor. The effects of organic capping agents such as Oleic acid, Ethylene Diamine Tetra Acetic acid (EDTA and Cetryl Tri Methyl Butoxide (CTAB on the size and morphology of the nanoparticles were studied. Characterization techniques such as X-ray diffraction (XRD, Fourier Transform-Infrared spectroscopy (FT-IR, Photoluminescence (PL Field Emission Scanning Electron Microscopy (FE-SEM, Energy Dispersive Spectroscopy (EDS and Transmission Electron Microscopy (TEM were used to analyse the prepared nanoparticles for their physical, structural and optical properties. The characterization studies reveal that the synthesized PbO nanoparticles had well defined crystalline structure and sizes in the range of 25 nm to 36 nm for capping agents used and 40 nm for pure PbO nanoparticles.

  16. Synthesis and Characterization of CdSe Nanocrystals Capped by CdS

    Institute of Scientific and Technical Information of China (English)

    SU Xing-guang; LIN Zhang-bi; HU Hai; ZHANG Jia-hua; JIN Qin-han

    2003-01-01

    CdSe semiconductor nanocrystals capped by CdS were synthesized in the aqueous solution with 2-mercaptoethanol as the stabilizer. The CdS capping with a higher band-gap than that of the core crystallite has successfully eliminated the surface traps. Optical absorption and fluorescence emission spectra were used to probe the effect of CdS passivation on the electronic structure of the nanocrystals. The composite CdSe/CdS nanocrystals exhibit strong, narrow(FWHM≤40 nm) and stable band-edge photoluminescence. X-ray powder diffraction, transmission electron microscopy and X-ray photoelectron spectroscopy were used to analyze the composite nanocrystals and determine their average size, size distribution, shape, internal structure and elemental composition.

  17. Characterizing Lyman Alpha Scattering in Nearby Galaxies

    Science.gov (United States)

    Bridge, Joanna; Hayes, Matthew; Melinder, Jens; Östlin, Göran; Gronwall, Caryl

    2017-01-01

    The hydrogen emission line of Lyman alpha (Lyα) has long been recognized as key to studying high redshift star-forming galaxies. However, due to the resonance of the emission line, the path that a Lyα photon takes from emission to eventual escape from the galaxy is essentially a mystery. This scattering poses a problem for using Lyα as a key emission feature of galaxies because it results in Lyα not being observed in all star-forming galaxies, and, in galaxies where it is observed, the place where the photon is originally emitted and where it is observed are two very different things. We discuss here how the Lyman-Alpha Reference Sample (LARS) provides a unique sample of 14 nearby (0.02 Space Telescope imaging. We compare the Lyα/Hα ratios with those expected from pure dust attenuation models, finding that in some cases significant positive departures are found on small scales, consistent with geometrical effects being important on sizes comparable to the HII regions. We then develop a simple scattering model in which we are able to estimate the average path length a Lyα photon travels with respect to non-resonant radiation, and quantifiy the excess dust optical depth to which Lyα radiation may be susceptible.

  18. Phosphogypsum capping depth affects revegetation and hydrology in Western Canada.

    Science.gov (United States)

    Jackson, Mallory E; Naeth, M Anne; Chanasyk, David S; Nichol, Connie K

    2011-01-01

    Phosphogypsum (PG), a byproduct of phosphate fertilizer manufacturing, is commonly stacked and capped with soil at decommissioning. Shallow (0, 8, 15, and 30 cm) and thick (46 and 91 cm) sandy loam caps on a PG stack near Fort Saskatchewan, Alberta, Canada, were studied in relation to vegetation establishment and hydrologic properties. Plant response was evaluated over two growing seasons for redtop ( L.), slender wheatgrass ( (Link) Malte ex H.F. Lewis), tufted hairgrass ( (L.) P. Beauv.), and sheep fescue ( L.) and for a mix of these grasses with alsike clover ( L.). Water content below the soil-PG interface was monitored with time-domain reflectometry probes, and leachate water quantity and quality at a depth of 30 cm was measured using lysimeters. Vegetation responded positively to all cap depths relative to bare PG, with few significant differences among cap depths. Slender wheatgrass performed best, and tufted hairgrass performed poorly. Soil caps <1 m required by regulation were sufficient for early revegetation. Soil water fluctuated more in shallow than in thick caps, and water content was generally between field capacity and wilting point regardless of cap depth. Water quality was not affected by cap depths ≤30 cm. Leachate volumes at 30 cm from distinct rainfall events were independent of precipitation amount and cap depth. The study period had lower precipitation than normal, yet soil caps were hospitable for plant growth in the first 2 yr of establishment.

  19. GPS/CAPS dual-mode software receiver

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The positioning of the GPS or Chinese Area Positioning System (CAPS) software receiver was developed on a software receiver platform. The structure of the GPS/CAPS dual-mode software receiver was put forward after analyzing the differences in the satellite identification, ranging code, spread spectrum, coordinate system, time system, carrier band, and navigation data between GPS and CAPS. Based on Matlab software on a personal computer, baseband signal processing and positioning procedures were completed using real GPS and CAPS radio frequency signals received by two antennas. Three kinds of experiments including GPS positioning, CAPS positioning, and GPS/CAPS positioning were carried out. Stability and precision of the results were analyzed and compared. The experimental results show that the precision of CAPS is similar to that of GPS, while the positioning precision of the GPS/CAPS dual-mode software receiver is 1-2 m higher than that of CAPS or GPS. The smallest average variance of the positioning can be obtained by using the GPS/CAPS dual-mode software receiver.

  20. GPS/CAPS dual-mode software receiver

    Institute of Scientific and Technical Information of China (English)

    NING ChunLin; SHI HuLi; HU Chao

    2009-01-01

    The positioning of the GPS or Chinese Area Positioning System (CAPS) software receiver was developed on a software receiver platform.The structure of the GPSlCAPS dual-mode software receiver was put forward after analyzing the differences in the satellite identification,ranging code,spread spectrum,coordinate system,time system,carrier band,and navigation data between GPS and CAPS.Based on Matlab software on a personal computer,baseband signal processing and positioning procedures were completed using real GPS and CAPS radio frequency signals received by two antennas.Three kinds of experiments including GPS positioning,CAPS positioning,and GPS/CAPS positioning were carried out.Stability and precision of the results were analyzed and compared.The experimental results show that the precision of CAPS is similar to that of GPS,while the positioning precision of the GPS/CAPS dual-mode software receiver is 1-2 m higher than that of CAPS or GPS.The smallest average variance of the positioning can be obtained by using the GPS/CAPS dual-mode software receiver.

  1. Lyman Alpha Spicule Observatory (LASO)

    Science.gov (United States)

    Chamberlin, P. C.; Allred, J. C.; Airapetian, V.; Gong, Q.; Mcintosh, S. W.; De Pontieu, B.; Fontenla, J. M.

    2011-12-01

    The Lyman Alpha Spicule Observatory (LASO) sounding rocket will observe small-scale eruptive events called "Rapid Blue-shifted Events" (RBEs) [Rouppe van der Voort et al., 2009], the on-disk equivalent of Type-II spicules, and extend observations that explore their role in the solar coronal heating problem [De Pontieu et al., 2011]. LASO utilizes a new and novel optical design to simultaneously observe two spatial dimensions at 4.2" spatial resolution (2.1" pixels) over a 2'x2' field of view with high spectral resolution of 66mÅ (33mÅ pixels) across a broad 20Å spectral window. This spectral window contains three strong chromospheric and transition region emissions and is centered on the strong Hydrogen Lyman-α emission at 1216Å. This instrument makes it possible to obtain new data crucial to the physical understanding of these phenomena and their role in the overall energy and momentum balance from the upper chromosphere to lower corona. LASO was submitted March 2011 in response to the ROSES SHP-LCAS call.

  2. Method of demonstrating calcium in human foot by neutron activation of (. cap alpha. , N)-sources

    Energy Technology Data Exchange (ETDEWEB)

    Zaychik, V.E.; Kondrashov, A.E.; Morukov, B.V.

    Bone demineralization during long-term exposure to weightlessness and hypokinesia is presently a universally recognized fact. A method is described which employs neutron activation analysis for a direct quantitative in vivo assay of calcium in the human foot. When the foot is exposed to neutrons, the stable nuclide Ca/sup 46/ is converted into the radionuclide Ca/sup 49/. The gamma radiation emitted by Ca/sup 49/ is then measured spectrometrically. A special device, developed for the delivery of neutrons to the foot, consists of a stainless steel tank filled with water, surrounded on the side by lithium-containing screens. A cassette with neutron sources is at the bottom of the tank and can be delivered to the desired position in channel-driver carriers. A special footrest provides support during irradiation. The spectrometry unit, consisting of 4 scintillation counters, also is equipped with a specially designed footrest. The maximum relative error of a single measurement did not exceed 4.82%. The mean equivalent dose in the foot was about 1 rem, a dose low enough to permit examinations three times a year, if necessary.

  3. Workshop on A/sup. cap alpha. / physics. Copies of transparencies

    Energy Technology Data Exchange (ETDEWEB)

    Voyvodic, L.

    1982-03-04

    This one-day workshop focussed on A-dependent effects in high energy particle production. The sessions covered: hard scattering; soft collisions; Tevatron experiments and idea sessions. The report is a collection of vugraphs used. (GHT)

  4. Polar cap arcs from the magnetosphere to the ionosphere: kinetic modelling and observations by Cluster and TIMED

    Directory of Open Access Journals (Sweden)

    R. Maggiolo

    2012-02-01

    Full Text Available On 1 April 2004 the GUVI imager onboard the TIMED spacecraft spots an isolated and elongated polar cap arc. About 20 min later, the Cluster satellites detect an isolated upflowing ion beam above the polar cap. Cluster observations show that the ions are accelerated upward by a quasi-stationary electric field. The field-aligned potential drop is estimated to about 700 V and the upflowing ions are accompanied by a tenuous population of isotropic protons with a temperature of about 500 eV.

    The magnetic footpoints of the ion outflows observed by Cluster are situated in the prolongation of the polar cap arc observed by TIMED GUVI. The upflowing ion beam and the polar cap arc may be different signatures of the same phenomenon, as suggested by a recent statistical study of polar cap ion beams using Cluster data.

    We use Cluster observations at high altitude as input to a quasi-stationary magnetosphere-ionosphere (MI coupling model. Using a Knight-type current-voltage relationship and the current continuity at the topside ionosphere, the model computes the energy spectrum of precipitating electrons at the top of the ionosphere corresponding to the generator electric field observed by Cluster. The MI coupling model provides a field-aligned potential drop in agreement with Cluster observations of upflowing ions and a spatial scale of the polar cap arc consistent with the optical observations by TIMED. The computed energy spectrum of the precipitating electrons is used as input to the Trans4 ionospheric transport code. This 1-D model, based on Boltzmann's kinetic formalism, takes into account ionospheric processes such as photoionization and electron/proton precipitation, and computes the optical and UV emissions due to precipitating electrons. The emission rates provided by the Trans4 code are compared to the optical observations by TIMED. They are similar in size and intensity. Data and modelling results are consistent with the

  5. Quantifying Solar Wind-Polar Cap Interactions

    Science.gov (United States)

    Urban, K. D.; Gerrard, A. J.; Lanzerotti, L. J.; Weatherwax, A. T.; Huang, Y.

    2015-12-01

    It is well known that the solar wind is a major driver of ultra-low frequency [ULF] power at ground locations from low to high latitudes. However, due to the scarcity of deep polar cap magnetometer sites, it is not clear when, where, or if this is true deep inside the polar cap on open field lines where interplanetary magnetic field [IMF] ULF waves could possibly be directly detected. Given recent observations of very large Joule heating estimates from DMSP data, together with the large heating reported by the CHAMP satellite, it is important to understand the degree to which ULF waves in the solar wind can directly cause such heating. Using a time series of lagged correlation sequences ("dynamic correlograms") between GSM Bz ULF power (computed via data obtained from NASA's Advanced Composition Explorer [ACE] ahead of Earth in the solar wind) and the horizontal ULF power (H^2=N^2+E^2) from ground-based magnetometers in Earth's southern polar cap, we investigate the direct penetration of ULF waves from the solar wind into the polar ionosphere during a gamut of space weather conditions at a distributed network of Automated Geophysical Observatories [AGOs] in Antarctica. To infer causation, a predicted lag correlation maximum at each time step is computed by simply dividing the associated distance of ACE from Earth by the concurrent bulk solar wind speed. This technique helps parse out direct penetration of solar wind ULF waves from other sources (e.g., via leakage from closed field line resonances due to the bulk solar wind plasma viscously interacting at dawn/dusk flanks inducing Kelvin-Helmholtz instabilities [KHI] or compressional modes induced by impulses in solar wind dynamic pressure). The identified direct-penetrating ULF waves are related to the DMSP-derived Poynting fluxes by regression analysis, and conclusions are drawn for the importance of the ULF source for the measured heating.

  6. MARK II end cap calorimeter electronics

    Energy Technology Data Exchange (ETDEWEB)

    Jared, R.C.; Haggerty, J.S.; Herrup, D.A.; Kirsten, F.A.; Lee, K.L.; Olson, S.R.; Wood, D.R.

    1985-10-01

    An end cap calorimeter system has been added to the MARK II detector in preparation for its use at the SLAC Linear Collider. The calorimeter uses 8744 rectangular proportional counter tubes. This paper describes the design features of the data acquisition electronics that has been installed on the calorimeter. The design and use of computer-based test stands for the amplification and signal-shaping components is also covered. A portion of the complete system has been tested in a beam at SLAC. In these initial tests, using only the calibration provided by the test stands, a resolution of 18%/..sqrt..E was achieved.

  7. ARCADE 2 Observations of Galactic Radio Emission

    CERN Document Server

    Kogut, A; Levin, S M; Limon, M; Lubin, P M; Mirel, P; Seiffert, M; Singal, J; Villela, T; Wollack, E; Wünsche, C A

    2009-01-01

    We use absolutely calibrated data from the ARCADE 2 flight in July 2006 to model Galactic emission at frequencies 3, 8, and 10 GHz. The spatial structure in the data is consistent with a superposition of free-free and synchrotron emission. Emission with spatial morphology traced by the Haslam 408 MHz survey has spectral index beta_synch = -2.5 +/- 0.1, with free-free emission contributing 0.10 +/- 0.01 of the total Galactic plane emission in the lowest ARCADE 2 band at 3.15 GHz. We estimate the total Galactic emission toward the polar caps using either a simple plane-parallel model with csc|b| dependence or a model of high-latitude radio emission traced by the COBE/FIRAS map of CII emission. Both methods are consistent with a single power-law over the frequency range 22 MHz to 10 GHz, with total Galactic emission towards the north polar cap T_Gal = 0.498 +/- 0.028 K and spectral index beta = -2.55 +/- 0.03 at reference frequency 1 GHz. The well calibrated ARCADE 2 maps provide a new test for spinning dust emi...

  8. H-alpha spectra of dynamic chromospheric processes in five well-observed X-ray flares

    Science.gov (United States)

    Canfield, Richard C.; Penn, Matthew J.; Wulser, Jean-Pierre; Kiplinger, Alan L.

    1990-01-01

    Simultaneous H-alpha and hard X-ray (HXR) spectra were obtained for five solar flares to determine the relationship of H-alpha profiles and the nonthermal part of the flare represented by the hard X-ray burst. All five flares exhibited impulsive-phase redshifted H-alpha in emission, which was temporarily and spatially associated with intense HXR emission and broad impulsive-phase H-alpha wings. A few small regions within two flares showed a blueshifted H-alpha emission which appeared only early in the impulsive phase and was temporally correlated with the HXR emission but not with broad H-alpha wings. Finally, there were both redshifted and blueshifted absorption spectra with properties fully consistent with those known for erupting and untwisting filaments.

  9. Cap-and-Trade Modeling and Analysis: Congested Electricity Market Equilibrium

    Science.gov (United States)

    Limpaitoon, Tanachai

    This dissertation presents an equilibrium framework for analyzing the impact of cap-and-trade regulation on transmission-constrained electricity market. The cap-and-trade regulation of greenhouse gas emissions has gained momentum in the past decade. The impact of the regulation and its efficacy in the electric power industry depend on interactions of demand elasticity, transmission network, market structure, and strategic behavior of firms. I develop an equilibrium model of an oligopoly electricity market in conjunction with a market for tradable emissions permits to study the implications of such interactions. My goal is to identify inefficiencies that may arise from policy design elements and to avoid any unintended adverse consequences on the electric power sector. I demonstrate this modeling framework with three case studies examining the impact of carbon cap-and-trade regulation. In the first case study, I study equilibrium results under various scenarios of resource ownership and emission targets using a 24-bus IEEE electric transmission system. The second and third case studies apply the equilibrium model to a realistic electricity market, Western Electricity Coordinating Council (WECC) 225-bus system with a detailed representation of the California market. In the first and second case studies, I examine oligopoly in electricity with perfect competition in the permit market. I find that under a stringent emission cap and a high degree of concentration of non-polluting firms, the electricity market is subject to potential abuses of market power. Also, market power can occur in the procurement of non-polluting energy through the permit market when non-polluting resources are geographically concentrated in a transmission-constrained market. In the third case study, I relax the competitive market structure assumption of the permit market by allowing oligopolistic competition in the market through a conjectural variation approach. A short-term equilibrium

  10. Comparative analysis of the Tyr-kinases CapB1 and CapB2 fused to their cognate modulators CapA1 and CapA2 from Staphylococcus aureus.

    Directory of Open Access Journals (Sweden)

    Jakub Gruszczyk

    Full Text Available A particular class of tyrosine-kinases sharing no structural similarity with eukaryotic tyrosine-kinases has been evidenced in a large array of bacterial species. These bacterial tyrosine-kinases are able to autophosphorylate on a C-terminal tyrosine-rich motif. Their autophosphorylation has been shown to play a crucial role in the biosynthesis or export of capsular polysaccharide. The analysis of the first crystal structure of the staphylococcal tyrosine kinase CapB2 associated with the activating domain of the transmembrane modulator CapA1 had brought conclusive explanation for both the autophosphorylation and activation processes. In order to explain why CapA1 activates CapB2 more efficiently than its cognate transmembrane modulator CapA2, we solved the crystal structure of CapA2B2 and compared it with the previously published structure of CapA1B2. This structural analysis did not provide the expected clues about the activation discrepancy observed between the two modulators. Staphylococcus aureus also encodes for a CapB2 homologue named CapB1 displaying more than 70% sequence similarity and being surprisingly nearly unable to autophosphorylate. We solved the crystal structure of CapA1B1 and carefully compare it with the structure of CapA1B2. The active sites of both proteins are highly conserved and the biochemical characterization of mutant proteins engineered to test the importance of small structural discrepancies identified between the two structures did not explain the inactivity of CapB1. We thus tested if CapB1 could phosphorylate other protein substrates or hydrolyze ATP. However, no activity could be detected in our in vitro assays. Taken together, these data question about the biological role of the homologous protein pairs CapA1/CapB1 and CapA2/CapB2 and we discuss about several possible interpretations.

  11. Macrophage Capping Protein CapG Is a Putative Oncogene Involved in Migration and Invasiveness in Ovarian Carcinoma

    Directory of Open Access Journals (Sweden)

    J. Glaser

    2014-01-01

    Full Text Available The actin binding protein CapG modulates cell motility by interacting with the cytoskeleton. CapG is associated with tumor progression in different nongynecologic tumor entities and overexpression in breast cancer cell lines correlates with a more invasive phenotype in vitro. Here, we report a significant CapG overexpression in 18/47 (38% of ovarian carcinomas (OC analyzed by qRealTime-PCR analyses. Functional analyses in OC cell lines through siRNA mediated CapG knockdown and CapG overexpression showed CapG-dependent cell migration and invasiveness. A single nucleotide polymorphism rs6886 inside the CapG gene was identified, affecting a CapG phosphorylation site and thus potentially modifying CapG function. The minor allele frequency (MAF of SNP rs6886 (c.1004A/G was higher and the homozygous (A/A, His335 genotype was significantly more prevalent in patients with fallopian tube carcinomas (50% as in controls (10%. With OC being one of the most lethal cancer diseases, the detection of novel biomarkers such as CapG could reveal new diagnostic and therapeutic targets. Moreover, in-depth analyses of SNP rs6886 related to FTC and OC will contribute to a better understanding of carcinogenesis and progression of OC.

  12. Suzaku X-ray Observations of the Fermi Bubbles: Northernmost Cap and Southeast Claw Discovered with MAXI-SSC

    CERN Document Server

    Tahara, Masaya

    2015-01-01

    We report on Suzaku observations of large-scale X-ray structures possibly related with the Fermi Bubbles obtained in 2013 with a total duration of ~ 80 ks. The observed regions were the: (i) northern cap (N-cap; l ~ 0 deg, 45 deg < b < 55 deg) seen in the Mid-band (1.7-4.0 keV) map recently provided by MAXI-SSC and (ii) southeast claw (SE-claw; l ~ 10 deg, -20 deg < b < -10 deg) seen in the ROSAT all-sky map and MAXI-SSC Low-band (0.7-1.7 keV) map. In each region, we detected diffuse X-ray emissions which are represented by a three component plasma model consisting of an unabsorbed thermal component (kT ~ 0.1 keV) from the Local Bubble, absorbed kT = 0.30+/-0.05 keV emission representing the Galactic Halo, and a power-law component due to the isotropic cosmic X-ray background radiation. The emission measure of the GH component in the SE-claw shows an excess by a factor of ~ 2.5 over the surrounding emission at 2 deg away. We also found a broad excess in the 1.7-4.0 keV count rates across the N-cap...

  13. Sediment Capping and Natural Recovery, Contaminant Transport Fundamentals With Applications to Sediment Caps

    Science.gov (United States)

    2005-09-01

    source concentration through time are often represented as first-order (exponential) decay processes and can be described by the equation t ot eCC λ...meter. This coupled with the relative homo - geneity of many capping materials should in most settings cause the effects asso- ciated with

  14. Procalcitonin and community-acquired pneumonia (CAP) in children.

    Science.gov (United States)

    Giulia, Bivona; Luisa, Agnello; Concetta, Scazzone; Bruna, Lo Sasso; Chiara, Bellia; Marcello, Ciaccio

    2015-12-07

    The role of procalcitonin (PCT) as a biomarker for sepsis in adults is well documented, while its role in infections affecting neonatal children remains controversial. Among these infections, Community-Acquired pneumonia (CAP) has been studied extensively, because it's the second cause of death in children in developing countries, and one of the most frequent causes of hospitalization in industrialized countries. The PubMed database and the Cochrane Library were used to search for the following keywords: CAP, procalcitonin, and children. Thirteen articles were studied to determine the role of PCT in CAP management, specifically its usefulness for distinguishing pneumococcal infections from viral and unknown infections, for predicting severity and the correct antibiotic treatment. This paper focuses on the studies performed to identify the best inflammatory biomarker for CAP management. Although there is an increase in studies confirming the usefulness of PCT in CAP management in children, further studies are needed to have better understanding of its role for pediatric CAP management.

  15. An examination of Mars' north seasonal polar cap using MGS: Composition and infrared radiation balance

    Science.gov (United States)

    Hansen, Gary B.

    2013-08-01

    A detailed analysis of data from one revolution of the Mars Global Surveyor (MGS) is presented. Approximately 80% of this revolution observes the mid-winter northern seasonal polar cap, which covers the surface to night. The surface composition and temperature are determined through analysis of 6-50 μm infrared spectra from the Thermal Emission Spectrometer (TES). The infrared radiative balance, which is the entire heat balance in the polar night except for small subsurface and atmospheric advection terms, is calculated for the surface and atmospheric column. The primary constituent, CO2 ice, also dominates the infrared spectral properties by variations in its grain size and by admixtures of dust and water ice, which cause large variations in the 20-50 μm emissivity. This is modified by incomplete areal coverage, and clouds or hazes. This quantitative analysis reveals CO2 grain radii ranging from ˜100 μm in isolated areas, to 1-5 mm in more widespread regions. The water ice content varies from none to about one part per thousand by mass, with a clear increase towards the periphery of the polar cap. The dust content is typically a few parts per thousand by mass, but is as much as an order of magnitude less abundant in "cold spot" regions, where the low emissivity of pure CO2 ice is revealed. This is the first quantitative analysis of thermal spectra of the seasonal polar cap and the first to estimate water ice content. Our models show that the cold spots represent cleaner, dust-free ice rather than finer grained ice than the background. Our guess is that the dust in cold spots is hidden in the center of the CO2 frost particles rather than not present. The fringes of the cap have more dust and water ice, and become patchy, with warmer water snow filling the gaps on the night side, and warmer bare soil on the day side. A low optical depth (night side, and appears with smaller optical depth on the day side. The infrared radiative balance at the surface is typically

  16. Alpha/sub 1/ receptor coupling events initiated by methoxy-substituted tolazoline partial agonists

    Energy Technology Data Exchange (ETDEWEB)

    Wick, P.; Keung, A.; Deth, R.

    1986-03-01

    A series of mono- and dimethyoxy substituted tolazoline derivatives, known to be partial agonists at the alpha/sub 1/ receptor, were compared with the ..cap alpha../sub 1/ selective full agonist phenylephrine (PE) on isolated strips of rabbit aorta Agonist activity was evaluated in contraction, /sup 45/Ca influx, /sup 45/Ca efflux, and /sup 32/P-Phospholipid labelling studies. Maximum contractile responses for the 2-, 3-, and 3, 5- methoxy substituted tolazoline derivatives (10/sup -5/M) were 53.8, 67.6 and 99.7% of the PE (10/sup -5/M) response respectively. These same partial agonists caused a stimulation of /sup 45/Ca influx to the extent of 64, 86, and 95% of the PE response respectively. In /sup 45/Ca efflux studies, (a measure of the intracellular Ca/sup +2/ release) the tolazolines caused: 30%, 63%, and 78% of the PE stimulated level. /sup 32/P-Phosphatidic acid (PA) labelling was measured as an index of PI turnover after ..cap alpha../sub 1/ receptor stimulation. Compared to PE, the 2-, 3-, and 3,5- methoxy substituted tolazoline derivatives caused 22, 46, and 72% PA labelling. The above values are all in reasonable accord with the rank order or agonist activity shown in maximum contractile responses. The results of this investigation suggest that partial agonists stimulate ..cap alpha.. receptor coupling events at a level which is quantitatively comparable to their potencies in causing contraction of arterial smooth muscle.

  17. Arrays of magnetic nanoparticles capped with alkylamines

    Indian Academy of Sciences (India)

    P John Thomas; P Saravanan; G U Kulkarni; C N R Rao

    2002-02-01

    Magnetic metal and metal oxide nanoparticles capped with alkylamines have been synthesized and characterized by transmission electron microscopy, X-ray diffraction, energy dispersive X-ray analysis and magnetization measurements. Core-shell Pd–Ni particles with composition, Pd561Ni3000, (diameter ∼ 3.3 nm) are superparamagnetic at 5 K and organize themselves into two-dimensional crystalline arrays. Similar arrays are obtained with Pd561Ni3000Pd1500 nanoparticles containing an additional Pd shell. Magnetic spinel particles of -Fe2O3, Fe3O4 and CoFe2O4 of average diameters in the 4–6 nm range coated with octylamine are all supermagnetic at room temperature and yield close-packed disordered arrays. Relatively regular arrays are formed by dodecylamine-capped Fe3O4 nanoparticles (∼ 8.6 nm diameter) while well-ordered hexagonal arrays were obtained with octylamine-covered Co3O4 nanoparticles (∼ 4.2 nm diameter).

  18. Comparison of Polar Cap (PC) index calculations.

    Science.gov (United States)

    Stauning, P.

    2012-04-01

    The Polar Cap (PC) index introduced by Troshichev and Andrezen (1985) is derived from polar magnetic variations and is mainly a measure of the intensity of the transpolar ionospheric currents. These currents relate to the polar cap antisunward ionospheric plasma convection driven by the dawn-dusk electric field, which in turn is generated by the interaction of the solar wind with the Earth's magnetosphere. Coefficients to calculate PCN and PCS index values from polar magnetic variations recorded at Thule and Vostok, respectively, have been derived by several different procedures in the past. The first published set of coefficients for Thule was derived by Vennerstrøm, 1991 and is still in use for calculations of PCN index values by DTU Space. Errors in the program used to calculate index values were corrected in 1999 and again in 2001. In 2005 DMI adopted a unified procedure proposed by Troshichev for calculations of the PCN index. Thus there exists 4 different series of PCN index values. Similarly, at AARI three different sets of coefficients have been used to calculate PCS indices in the past. The presentation discusses the principal differences between the various PC index procedures and provides comparisons between index values derived from the same magnetic data sets using the different procedures. Examples from published papers are examined to illustrate the differences.

  19. Selection of satellite constellation framework of CAPS

    Institute of Scientific and Technical Information of China (English)

    HAN YanBen; MA LiHua; QIAO QiYuan; YIN ZhiQiang; AI GuoXiang

    2009-01-01

    Based on the idea of transmitting the satellite navigation and positioning system,taking the distribution and variation of the Position Dilution of Precision factor (PDOP),which is closely related with the precision of navigation and positioning,within the China area as the primary criterion,we analyze and discuss the tentative plan of constellation configuration consisting of geosynchronous orbit (GEO) communication satellites and inclined geosynchronous orbit (IGSO) satellites for the transmitting Chinese Area Positioning System (CAPS).We emphatically consider the effect on the PDOP by the three major orbit parameters including the inclination,eccentricity and right ascension of the ascending node (RAAN) of IGSO satellites,to research the strategies of the constellation configuration of CAPS through software emulation.Various constellation configurations are analyzed and compared and the results show that the constellation configuration,consisting of three IGSO communication satellites in three orbits with the same inclination as 50°,the difference in RAAN as 120°and the same "8" shaped ground track centered near 115°E and four or five GEO communication satellites within 60°E to 150°E,can satisfy the requirement that Chinese domain is availably covered end the navigation and positioning with high precision could be obtained.Three relatively excellent constellation configurations are initially suggested and some concerned issues are discussed in this work.

  20. Selection of satellite constellation framework of CAPS

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Based on the idea of transmitting the satellite navigation and positioning system, taking the distribution and variation of the Position Dilution of Precision factor (PDOP), which is closely related with the precision of navigation and positioning, within the China area as the primary criterion, we analyze and discuss the tentative plan of constellation configuration consisting of geosynchronous orbit (GEO) communication satellites and inclined geosynchronous orbit (IGSO) satellites for the transmitting Chinese Area Positioning System (CAPS). We emphatically consider the effect on the PDOP by the three major orbit parameters including the inclination, eccentricity and right ascension of the ascend- ing node (RAAN) of IGSO satellites, to research the strategies of the constellation configuration of CAPS through software emulation. Various constellation configurations are analyzed and compared and the results show that the constellation configuration, consisting of three IGSO communication satellites in three orbits with the same inclination as 50°, the difference in RAAN as 120° and the same "8" shaped ground track centered near 115°E and four or five GEO communication satellites within 60°E to 150°E, can satisfy the requirement that Chinese domain is availably covered and the navigation and positioning with high precision could be obtained. Three relatively excellent constellation configurations are initially suggested and some concerned issues are discussed in this work.

  1. Lowering the YE+1 end-cap for CMS

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    On 9 January 2007, the massive YE+1 end-cap was lowered into the CMS cavern. This is a very precise process as the crane must lower the end-cap through minimal clearance without tilt or sway. Once in the cavern, the end-cap is then positioned over the end of the barrel to detect particles produced in collisions that travel close to the axis of the beams.

  2. ALPHA MIS: Reference manual

    Energy Technology Data Exchange (ETDEWEB)

    Lovin, J.K.; Haese, R.L.; Heatherly, R.D.; Hughes, S.E.; Ishee, J.S.; Pratt, S.M.; Smith, D.W.

    1992-02-01

    ALPHA is a powerful and versatile management information system (MIS) initiated and sponsored and by the Finance and Business Management Division of Oak Ridge National Laboratory, who maintain and develop it in concert with the Business Systems Division for its Information Center. A general-purpose MIS, ALPHA allows users to access System 1022 and System 1032 databases to obtain and manage information. From a personal computer or a data terminal, Energy Systems employees can use ALPHA to control their own report reprocessing. Using four general commands (Database, Select, Sort, and Report) they can (1) choose a mainframe database, (2) define subsets within it, (3) sequentially order a subset by one or more variables, and (4) generate a report with their own or a canned format.

  3. Design and Performance of Capping Layers for EUV Multilayer Mirrors

    Energy Technology Data Exchange (ETDEWEB)

    Bajt, S; Chapman, H N; Nuygen, N; Alameda, J; Robinson, J C; Malinowski, M; Gullikson, E; Aquila, A; Tarrio, C; Grantham, S

    2003-03-10

    The reflectance stability of multilayer coatings for extreme ultraviolet lithography (EUVL) in a commercial tool environment is of uttermost importance to ensure continuous exposures with minimum maintenance cost. We have made substantial progress in designing the protective capping layer coatings, understanding their performance and estimating their lifetimes based on accelerated electron beam and EUV exposure studies. Our current capping layer coatings have about 40 times longer lifetimes than Si-capped multilayer optics. Nevertheless, the lifetime of current Ru-capped multilayers is too short to satisfy commercial tool requirements and further improvements are essential.

  4. Effect of swim cap model on passive drag.

    Science.gov (United States)

    Gatta, Giorgio; Zamparo, Paola; Cortesi, Matteo

    2013-10-01

    Hydrodynamics plays an important role in swimming because even small decreases in a swimmer's drag can lead to performance improvements. During the gliding phases of a race, the head of a swimmer is an important point of impact with the fluid, and the swim cap, even if it covers only a small portion of the swimmer's body, can have an influence on drag. The purpose of this study was to investigate the effects on passive drag (Dp) of wearing 3 different types of swim caps (LSC: a lycra cap; CSC: a silicone cap; HSC: a silicone helmet cap without seams). Sixteen swimmers were tested at 3 velocities (1.5, 1.7, 1.9 m·s), and the Dp measurements were repeated at each condition 5 times. A statistical analysis revealed significant differences in drag (p swim cap is the most rigid, the most adherent to the swimmer's head, and does not allow the formation of wrinkles compared with the other 2 investigated swim caps. Therefore, the following conclusions can be made: (a) swimmers should take care when selecting their swim cap if they want to improve the fluid dynamics at the "leading edge" of their body and (b) because Dp is affected by the swim cap model, care should be taken when comparing data from different studies, especially at faster investigated speeds.

  5. Influenza A virus preferentially snatches noncoding RNA caps

    OpenAIRE

    2015-01-01

    Influenza A virus (IAV) lacks the enzyme for adding 5′ caps to its RNAs and snatches the 5′ ends of host capped RNAs to prime transcription. Neither the preference of the host RNA sequences snatched nor the effect of cap-snatching on host processes is completely defined. Previous studies of influenza cap-snatching used poly(A)-selected RNAs from infected cells or relied on annotated host genes to define the snatched host RNAs, and thus lack details on many noncoding host RNAs including snRNAs...

  6. Analyses of Current And Wave Forces on Velocity Caps

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Buhrkall, Jeppe; Eskesen, Mark C. D.;

    2015-01-01

    Velocity caps are often used in connection with for instance offshore intake sea water for the use of for cooling water for power plants or as a source for desalinization plants. The intakes can also be used for river intakes. The velocity cap is placed on top of a vertical pipe. The vertical pipe......) this paper investigates the current and wave forces on the velocity cap and the vertical cylinder. The Morison’s force model was used in the analyses of the extracted force time series in from the CFD model. Further the distribution of the inlet velocities around the velocity cap was also analyzed in detail...

  7. AlphaSphere

    OpenAIRE

    Place, A.; Lacey, L.; Mitchell, T.

    2013-01-01

    The AlphaSphere is an electronic musical instrument featuring a series of tactile, pressure sensitive touch pads arranged in a spherical form. It is designed to offer a new playing style, while allowing for the expressive real-time modulation of sound available in electronic-based music. It is also designed to be programmable, enabling the flexibility to map a series of different notational arrangements to the pad-based interface.\\ud \\ud The AlphaSphere functions as an HID, MIDI and OSC devic...

  8. Emission Trading

    OpenAIRE

    2009-01-01

    The work concerns Emission Trading Scheme from perspektive of taxes and accounting. I should show problems with emission trading. The work concerns practical example of trading with emission allowance.

  9. Alpha-cluster Condensations in Nuclei and Experimental Approaches for their Studies

    CERN Document Server

    von Oertzen, Wolfram

    2010-01-01

    The formation of alpha-clusters in nuclei close to the decay thresholds is discussed. These states can be considered to be boson-condensates, which are formed in a second order phase transition in a mixture of nucleons and alpha-particles. The de Broglie wavelength of the alpha-particles is larger than the nuclear diameter, therefore the coherent properties of the alpha-particles give particular effects for the study of such states. The states are above the thresholds thus the enhanced emission of multiple-alphas into the same direction is observed. The probability for the emission of multiple-alphas is not described by Hauser-Feshbach theory for compound nucleus decay.

  10. Systematics of alpha decay half-life: new evaluations for alpha-emitter nuclides

    Energy Technology Data Exchange (ETDEWEB)

    Medeiros, E.L.; Rodrigues, M.M.N.; Duarte, S.B.; Tavares, O.A.P. E-mail: emil.cbpf.br

    2006-06-15

    A semiempirical model based on the quantum mechanical tunnelling mechanism of alpha emission from nuclei has been used to systematize the alpha decay half-lives of a set of 336 nuclides, comprising all the alpha-emitter nuclides whose T{sub 1/2} {sup a}lpha-data for ground-state to ground-state transitions of mutual angular momentum l = 0 are known. With a minimum of data rejection (only {approx} 5% of cases), the procedure has been successful in reproducing quite satisfactorily (within a factor {approx} 2) most of the cases ({approx} 80%) investigated. The few significant discrepancies found between measured and calculated results are analysed and discussed. Also reported is the prediction from the model for possible new alpha-emitter nuclides, namely {sup 180} W, {sup 184} Os, and {sup 228} Ra for which cases the calculated partial alpha decay half-lives fall within the range of half-lives measurable by the current techniques. (author)

  11. Relation of large-scale coronal X-ray structure and cosmic rays. I - Sources of solar wind streams as defined by X-ray emission and H-alpha absorption features

    Science.gov (United States)

    Krieger, A. S.; Nolte, J. T.; Sullivan, J. D.; Lazarus, A. J.; Mcintosh, P. S.; Gold, R. E.; Roelof, E. C.

    1975-01-01

    The large-scale structure of the corona and the interplanetary medium during Carrington rotations 1601-1607 is discussed relative to recurrent high-speed solar wind streams and their coronal sources. Only streams A, C, D, and F recur on more than one rotation. Streams A and D are associated with coronal holes, while C and F originate in the high corona (20-50 solar radii) over faint X-ray emissions. The association of the streams with holes is confirmed by earlier findings that there are no large equatorial holes without an associated high-speed stream and that the area of the equatorial region of coronal holes is highly correlated with the maximum velocity observed in the associated stream near 1 AU.

  12. Synthesis, surface characterization and optical properties of 3-thiopropionic acid capped ZnS:Cu nanocrystals

    Indian Academy of Sciences (India)

    Ashish Tiwari; S A Khan; R S Kher

    2011-08-01

    3-Thiopropionic acid (TPA) capped ZnS:Cu nanocrystals have been successfully synthesized by simple aqueous method. Powder X-ray diffraction (XRD) studies revealed the particle size to be 4.2 nm. Surface characterization of the nanocrystals by FTIR spectroscopy has been done and the structure for surface bound TPA based on spectral analysis was proposed. The optical studies were done using UV-VIS spectroscopy and particle size and diameter polydispersity index (DPI) were calculated. Photoluminescence (PL) spectrum reveals emission related to the transition from conduction band of ZnS to 2 level of Cu2+. Electron microscopy was also done by scanning electron microscopy (SEM).

  13. THE IMPACT OF THE CAP-AND-TRADE SYSTEM ON SUSTAINABLE DEVELOPMENT IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Balint (Platon Judit

    2010-12-01

    Full Text Available The issue of pollution is an important contemporary issue. Within the last 20 years, there have been global studies on how to stop global warming. The European Union is the world leader in concrete measures undertaken in this respect. The introduction of the cap-and-trade system, begun in 2005 with the carbon emission certificate trade mechanism is considered a a modest succes that needs perfecting. The new EU directives of 2009, that come into effect in 2013, test member countries in the area of conventional and renewable energy strategies which have to be adapted to the national environmental protection strategies.

  14. Tailoring the physical properties of thiol-capped PbS quantum dots by thermal annealing.

    Science.gov (United States)

    Turyanska, L; Elfurawi, U; Li, M; Fay, M W; Thomas, N R; Mann, S; Blokland, J H; Christianen, P C M; Patanè, A

    2009-08-05

    We show that the thermal annealing of thiol-capped PbS colloidal quantum dots provides a means of narrowing the nanoparticle size distribution, increasing the size of the quantum dots and facilitating their coalescence preferentially along the 100 crystallographic axes. We exploit these phenomena to tune the photoluminescence emission of an ensemble of dots and to narrow the optical linewidth to values that compare with those reported at room temperature for single PbS quantum dots. We probe the influence of annealing on the electronic properties of the quantum dots by temperature dependent studies of the photoluminescence and magneto-photoluminescence.

  15. Effects of an InGaAs Cap Layer on the Optical Properties of InAs Quantum Dot Molecules

    Institute of Scientific and Technical Information of China (English)

    TIAN Peng; HUANG Li-Rong; YUAN Xiu-Hua; HUANG De-Xiu

    2011-01-01

    @@ Self-assembled InAs quantum dot molecules are grown on GaAs substrates without following any special protocols by using metal-organic chemical vapor deposition.The effects of indium composition and the thickness of the InGaAs cap layer on the optical properties of InAs quantum dot molecules are investigated by photoluminescence.With increasing indium composition and thickness of the InGaAs cap layer, the ground-state wavelength of the emission spectrum redshifts and the peak intensity decreases.In addition, the structural and optical properties of quantum dots and quantum dot molecules are comparatively studied, and the results show that when quantum dots turn into quantum dot molecules, the emission wavelength red shifts.

  16. Alpha Antihydrogen Experiment

    CERN Document Server

    Fujiwara, M C; Ashkezari, M D; Baquero-Ruiz, M; Bertsche, W; Bray, C C; Butler, E; Cesar, C L; Chapman, S; Charlton, M; Cesar, C L; Fajans, J; Friesen, T; Gill, D R; Hangst, J S; Hardy, W N; Hayano, R S; Hayden, M E; Humphries, A J; Hydomako, R; Jonsell, S; Kurchaninov, L; Lambo, R; Madsen, N; Menary, S; Nolan, P; Olchanski, K; Olin, A; Povilus, A; Pusa, P; Robicheaux, F; Sarid, E; Silveira, D M; So, C; Storey, J W; Thompson, R I; van der Werf, D P; Wilding, D; Wurtele, J S; Yamazaki, Y

    2011-01-01

    ALPHA is an experiment at CERN, whose ultimate goal is to perform a precise test of CPT symmetry with trapped antihydrogen atoms. After reviewing the motivations, we discuss our recent progress toward the initial goal of stable trapping of antihydrogen, with some emphasis on particle detection techniques.

  17. Case Study - Alpha

    Directory of Open Access Journals (Sweden)

    Stephen Leybourne

    2016-11-01

    Full Text Available This case study was developed from an actual scenario by Dr. Steve Leybourne of Boston University.  The case documents the historical evolution of an organization, and has been used successfully in courses dealing with organizational and cultural change, and the utilization of ‘soft skills’ in project-based management. This is a short case, ideal for classroom use and discussion.  The issues are easily accessible to students, and there is a single wide ranging question that allows for the inclusion of many issues surrounding strategic decision-making, and behavioural and cultural change. Alpha was one of the earlier companies in the USA to invest in large, edge-of-town superstores, with plentiful free vehicle parking, selling food and related household products. Alpha was created in the 1950s as a subsidiary of a major publicly quoted retail group.  It started business by opening a string of very large discount stores in converted industrial and warehouse premises in the south of the United States. In the early days shoppers were offered a limited range of very competitively priced products. When Alpha went public in 1981 it was the fourth largest food retailer in the US, selling an ever-widening range of food and non-food products.  Its success continued to be based on high volume, low margins and good value for money, under the slogan of ‘Alpha Price.’

  18. Alpha-mannosidosis

    DEFF Research Database (Denmark)

    Borgwardt, Line; Stensland, Hilde Monica Frostad Riise; Olsen, Klaus Juul;

    2015-01-01

    of the three subgroups of genotype/subcellular localisation and the clinical and biochemical data were done to investigate the potential relationship between genotype and phenotype in alpha-mannosidosis. Statistical analyses were performed using the SPSS software. Analyses of covariance were performed...

  19. Glaciers and ice caps outside Greenland

    Science.gov (United States)

    Sharp, Marin; Wolken, G.; Burgess, D.; Cogley, J.G.; Copland, L.; Thomson, L.; Arendt, A.; Wouters, B.; Kohler, J.; Andreassen, L.M.; O'Neel, Shad; Pelto, M.

    2015-01-01

    Mountain glaciers and ice caps cover an area of over 400 000 km2 in the Arctic, and are a major influence on global sea level (Gardner et al. 2011, 2013; Jacob et al. 2012). They gain mass by snow accumulation and lose mass by meltwater runoff. Where they terminate in water (ocean or lake), they also lose mass by iceberg calving. The climatic mass balance (Bclim, the difference between annual snow accumulation and annual meltwater runoff) is a widely used index of how glaciers respond to climate variability and change. The total mass balance (ΔM) is defined as the difference between annual snow accumulation and annual mass losses (by iceberg calving plus runoff).

  20. Cytocompatibility and Antibacterial Properties of Capping Materials

    Science.gov (United States)

    Arciola, Carla Renata; Monaco, Annachiara; Lombardini, Marco

    2014-01-01

    The aim of this study was to evaluate and compare the antimicrobial activity and cytocompatibility of six different pulp-capping materials: Dycal (Dentsply), Calcicur (Voco), Calcimol LC (Voco), TheraCal LC (Bisco), MTA Angelus (Angelus), and Biodentine (Septodont). To evaluate antimicrobial activity, materials were challenged in vitro with Streptococcus mutans, Streptococcus salivarius, and Streptococcus sanguis in the agar disc diffusion test. Cytocompatibility of the assayed materials towards rat MDPC-23 cells was evaluated at different times by both MTT and apoptosis assays. Results significantly differed among the different materials tested. Both bacterial growth inhibition halos and cytocompatibility performances were significantly different among materials with different composition. MTA-based products showed lower cytotoxicity and valuable antibacterial activity, different from calcium hydroxide-based materials, which exhibited not only higher antibacterial activity but also higher cytotoxicity. PMID:24959601

  1. Carpentier, la otra novela (cap. IV

    Directory of Open Access Journals (Sweden)

    Urbano Martínez Carmenate

    2014-06-01

    Full Text Available El presente ensayo está extraído de la obra inédita de Urbano Martínez Carmenate, Carpentier, la otra novela (cap. IV. Ofrece una mirada sobre los primeros años de la trayectoria profesional de Alejo Carpentier. Se muestra cómo, durante la década de 1920, se inicia como periodista y cronista teatral. A la vez, comienzan sus conexiones con el Grupo Minorista, que desempeña un papel destacado en la etapa republicana en Cuba. También se contempla su viaje a México en 1926, que constituye su primer contacto directo con la naturaleza y la cultura americanas.

  2. Carpentier, la otra novela (cap. IV

    Directory of Open Access Journals (Sweden)

    Urbano Martínez Carmenate

    2014-07-01

    Full Text Available El presente ensayo está extraído de la obra inédita de Urbano Martínez Carmenate, Carpentier, la otra novela (cap. IV. Ofrece una mirada sobre los primeros años de la trayectoria profesional de Alejo Carpentier. Se muestra cómo, durante la década de 1920, se inicia como periodista y cronista teatral. A la vez, comienzan sus conexiones con el Grupo Minorista, que desempeña un papel destacado en la etapa republicana en Cuba. También se contempla su viaje a México en 1926, que constituye su primer contacto directo con la naturaleza y la cultura americanas.

  3. Cytocompatibility and Antibacterial Properties of Capping Materials

    Directory of Open Access Journals (Sweden)

    Claudio Poggio

    2014-01-01

    Full Text Available The aim of this study was to evaluate and compare the antimicrobial activity and cytocompatibility of six different pulp-capping materials: Dycal (Dentsply, Calcicur (Voco, Calcimol LC (Voco, TheraCal LC (Bisco, MTA Angelus (Angelus, and Biodentine (Septodont. To evaluate antimicrobial activity, materials were challenged in vitro with Streptococcus mutans, Streptococcus salivarius, and Streptococcus sanguis in the agar disc diffusion test. Cytocompatibility of the assayed materials towards rat MDPC-23 cells was evaluated at different times by both MTT and apoptosis assays. Results significantly differed among the different materials tested. Both bacterial growth inhibition halos and cytocompatibility performances were significantly different among materials with different composition. MTA-based products showed lower cytotoxicity and valuable antibacterial activity, different from calcium hydroxide-based materials, which exhibited not only higher antibacterial activity but also higher cytotoxicity.

  4. Non-statistical decay and $\\alpha$-correlations in the $^{12}$C+$^{12}$C fusion-evaporation reaction at 95 MeV

    CERN Document Server

    Morelli, L; D'Agostino, M; Gulminelli, F; Bruno, M; Abbondanno, U; Appannababu, S; Barlini, S; Bini, M; Casini, G; Cinausero, M; Degerlier, M; Fabris, D; Gelli, N; Gramegna, F; Kravchuk, V L; Marchi, T; Pasquali, G; Piantelli, S; Valdré, S; Raduta, Ad R

    2014-01-01

    Multiple alpha coincidence and correlations are studied in the reaction $^{12}$C+$^{12}$C at 95 MeV for fusion-evaporation events completely detected in charge. Two specific channels with Carbon and Oxygen residues in coincidence with $\\alpha$-particles are addressed, which are associated with anomalously high branching ratios with respect the predictions by Hauser-Feshbach calculations. Triple alpha emission appears kinematically compatible with a sequential emission from a highly excited Mg. The phase space distribution of $\\alpha$-$\\alpha$ coincidences suggests a correlated emission from a Mg compound, leaving an Oxygen residue excited above the threshold for neutron decay. These observations indicate a preferential $\\alpha$ emission of $^{24}$Mg at excitation energies well above the threshold for $6-\\alpha$ decay.

  5. Monoterpene emission from ponderosa pine

    Science.gov (United States)

    Lerdau, Manual; Dilts, Stephen B.; Westberg, Hal; Lamb, Brian K.; Allwine, Eugene J.

    1994-01-01

    We explore the variability in monoterpene emissions from ponderosa pine beyond that which can be explained by temperature alone. Specifically, we examine the roles that photosynthesis and needle monoterpene concentrations play in controlling emissions. We measure monoterpene concentrations and emissions, photosynthesis, temperature, and light availability in the late spring and late summer in a ponderosa pine forest in central Oregon. We use a combination of measurements from cuvettes and Teflon bag enclosures to show that photosynthesis is not correlated with emissions in the short term. We also show that needle monoterpene concentrations are highly correlated with emissions for two compounds, alpha-pinene and beta-pinene, but that Delta-carene concentrations are not correlated with emissions. We suggest that direct effects of light and photosynthesis do not need to be included in emission algorithms. Our results indicate that the role of needle concentration bears further investigation; our results for alpha-pinene and beta-pinene are explainable by a Raoult's law relationship, but we cannot yet explain the cause of our results with Delta-carene.

  6. alpha-Synuclein budding yeast model: toxicity enhanced by impaired proteasome and oxidative stress.

    Science.gov (United States)

    Sharma, Nijee; Brandis, Katrina A; Herrera, Sara K; Johnson, Brandon E; Vaidya, Tulaza; Shrestha, Ruja; Debburman, Shubhik K

    2006-01-01

    Parkinson's disease (PD) is a common neurodegenerative disorder that results from the selective loss of midbrain dopaminergic neurons. Misfolding and aggregation of the protein alpha-synuclein, oxidative damage, and proteasomal impairment are all hypotheses for the molecular cause of this selective neurotoxicity. Here, we describe a Saccharomyces cerevisiae model to evaluate the misfolding, aggregation, and toxicity-inducing ability of wild-type alpha-synuclein and three mutants (A30P, A53T, and A30P/A53T), and we compare regulation of these properties by dysfunctional proteasomes and by oxidative stress. We found prominent localization of wild-type and A53T alpha-synuclein near the plasma membrane, supporting known in vitro lipid-binding ability. In contrast, A30P was mostly cytoplasmic, whereas A30P/A53T displayed both types of fluorescence. Surprisingly, alpha-synuclein was not toxic to several yeast strains tested. When yeast mutants for the proteasomal barrel (doa3-1) were evaluated, delayed alpha-synuclein synthesis and membrane association were observed; yeast mutant for the proteasomal cap (sen3-1) exhibited increased accumulation and aggregation of alpha-synuclein. Both sen3-1and doa3-1 mutants exhibited synthetic lethality with alpha-synuclein. When yeasts were challenged with an oxidant (hydrogen peroxide), alpha-synuclein was extremely lethal to cells that lacked manganese superoxide dismutase Mn-SOD (sod2Delta) but not to cells that lacked copper, zinc superoxide dismutase Cu,Zn-SOD (sod1Delta). Despite the toxicity, sod2Delta cells never displayed intracellular aggregates of alpha-synuclein. We suggest that the toxic alpha-synuclein species in yeast are smaller than the visible aggregates, and toxicity might involve alpha-synuclein membrane association. Thus, yeasts have emerged effective organisms for characterizing factors and mechanisms that regulate alpha-synuclein toxicity.

  7. IPHAS : Surveying the North Galactic Plane in H-alpha

    NARCIS (Netherlands)

    Drew, J.E.; Groot, P.J.; Morales-Rueda, L.; Roelofs, G.H.A.

    2005-01-01

    H-alpha emission is ubiquitous in our Galaxy. It traces ionised gas of assorted nebulae such as HII regions, planetary nebulae, Wolf-Rayet nebulae, and supernova remnants. It is a strong signature of active stars, interacting binaries, very massive stars (especially supergiants, Luminous Blue Variab

  8. Exploring 21CM - Lyman Alpha Emitter Synergies for SKA

    NARCIS (Netherlands)

    Dayal, Pratika; Hutter, Anne; Müller, Volker; Trott, C. M.

    2017-01-01

    We study the signatures of reionization and ionizing properties of the early galaxies in the cross-correlations between the 21cm emission from the spin-flip transition of neutral hydrogen (H I ) and the underlying galaxy population, in particular a sub-population of galaxies visible as Lyman Alpha E

  9. Polar cap index as a proxy for hemispheric Joule heating

    DEFF Research Database (Denmark)

    Chun, F.K.; Knipp, D.J.; McHarg, M.G.

    1999-01-01

    The polar cap (PC) index measures the level of geomagnetic activity in the polar cap based on magnetic perturbations from overhead ionospheric currents and distant field-aligned currents on the poleward edge of the nightside auroral oval. Because PC essentially measures the main sources of energy...

  10. Temperature Distribution within a Cold Cap during Nuclear Waste Vitrification

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, Derek R.; Schweiger, Michael J.; Riley, Brian J.; Pokorny, Richard; Hrma, Pavel R.

    2015-07-21

    The kinetics of the feed-to-glass conversion affects the waste vitrification rate in an electric melter. The primary area of interest in this conversion process is the cold cap, a layer of reacting feed on top of molten glass. Knowing the temperature profile within a cold cap will help determine its characteristics and relate them to the rate of glass production. The work presented here provides an experimental determination of the temperature distribution within the cold cap. Since a direct measurement of the temperature field within the cold cap is impracticable, an indirect method was developed where the textural features in a laboratory-made cold cap with a high-level waste feed were mapped as a function of position using optical microscopy, scanning electron microscopy, energy dispersive spectroscopy, and X-ray diffraction. To correlate the temperature distribution to microstructures within the cold cap, microstructures were identified of individual feed samples that were heat treated to set temperatures between 400°C and 1200°C and quenched. The temperature distribution within the cold cap was then established by correlating cold-cap regions with the feed samples of nearly identical structures and was compared with the temperature profile from a mathematical model.

  11. IN SITU REMEDIATION OF CONTAMINATED SEDIMENTS - ACTIVE CAPPING TECHNOLOGY

    Energy Technology Data Exchange (ETDEWEB)

    Knox, A.; Roberts, J.; Paller, M.; Reible, D.

    2010-09-02

    Active capping is a relatively new approach for treating contaminated sediments. It involves applying chemically reactive amendments to the sediment surface. The main role of active caps is to stabilize contaminants in contaminated sediments, lower the bioavailable pool of contaminants, and reduce the release of contaminants to the water column. Metals are common contaminants in many marine and fresh water environments as a result of industrial and military activities. The mobile, soluble forms of metals are generally considered toxic. Induced chemical precipitation of these metals can shift toxic metals from the aqueous phase to a solid, precipitated phase which is often less bioavailable. This approach can be achieved through application of sequestering agents such as rock phosphates, organoclays, zeolites, clay minerals, and biopolymers (e.g., chitosan) in active capping technology. Active capping holds great potential for a more permanent solution that avoids residual risks resulting from contaminant migration through the cap or breaching of the cap. In addition to identifying superior active capping agents, research is needed to optimize application techniques, application rates, and amendment combinations that maximize sequestration of contaminants. A selected set of active capping treatment technologies has been demonstrated at a few sites, including a field demonstration at the Savannah River Site, Aiken, SC. This demonstration has provided useful information on the effects of sequestering agents on metal immobilization, bioavailability, toxicity, and resistance to mechanical disturbance.

  12. 47 CFR 61.41 - Price cap requirements generally.

    Science.gov (United States)

    2010-10-01

    ... party to a merger, acquisition, or similar transaction shall continue to be subject to price cap... no later than one year following the effective date of such merger, acquisition, or similar... subject to price cap regulation, as that term is defined in § 61.3(ee), which are involved in...

  13. Recent advances and design considerations in capping systems

    Energy Technology Data Exchange (ETDEWEB)

    DiPippo, G.J.; Monteleone, M.J. [Eckenfelder Inc., Mahwah, NJ (United States)

    1996-12-31

    Capping systems for solid and hazardous waste management facilities and remedial applications have changed significantly over the years. Early designs were virtually monolithic, with little specification of functional properties. The evolution of capping systems has continued and was hastened by the application of geosynthetics and the diligence of those working in the industry in understanding the design considerations for and performance of various capping materials. Capping systems continue to evolve particularly with respect to the application and understanding of the geosynthetic components. Today the design of an effective cap with a total thickness of two feet, or even less as is discussed further below, is possible. Yet much more work remains in various areas such as more precise means of assessing stability, the effects of strain softening, design using seismic considerations, and the like. This paper describes various recent advances in cap design. Three of these advances are covered in some detail; namely, geosynthetic clay layers, subdrainage design using high capacity geonets, and a thin cap section using direct asphalt overlay of geosynthetics for industrial site applications. Several other advances and design considerations are more briefly addressed to illustrate the breadth of the evolution of capping systems.

  14. ATLAS end-caps 
on the move

    CERN Multimedia

    2007-01-01

    Two delicate and spectacular transport operations have been performed for ATLAS in recent weeks: the first end-cap tracker was installed in its final position, and one of the huge end-caps of the toroid magnet was moved to the top of the experiment’s shaft.

  15. HB Hillingdon [alpha46(CE4)Phe-->Val (alpha1 Or alpha2)]: a new alpha chain hemoglobin variant.

    Science.gov (United States)

    Babb, Anna; Solaiman, Susannah; Green, Brian N; Mantio, Debbie; Patel, Ketan

    2009-01-01

    Routine antenatal hemoglobinopathy screening detected a new alpha chain variant that eluted with Hb A(2) on cation exchange high performance liquid chromatography (HPLC) in a lady of Sri Lankan origin who had normal hematological indices. The mutation was identified by electrospray ionization mass spectrometry (ESI-MS) as alpha46(CE4)Phe-->Val, inferring that the variant was due to a single base change at codon 46 (TTC>GTC) of the alpha1- or alpha2-globin genes.

  16. Keck Spectroscopy of Faint 3alpha emission

    CERN Document Server

    Stark, Daniel P; Chiu, Kuenley; Ouchi, Masami; Bunker, Andrew

    2010-01-01

    We present results from a new Keck spectroscopic survey of UV-faint LBGs in the redshift range 3emission much more frequently than luminous systems, and that at fixed luminosity, the prevalence of strong Lya emissio...

  17. Progress in LAr EndCap Calorimetry: News from the Hadronic EndCap Group.

    CERN Multimedia

    Oram, C.J.

    With module production and testing completed for the Hadronic EndCap calorimeter, the attention of the HEC group is heavily directed towards wheel assembly in building 180. Three of the four HEC wheels are now assembled and rotated, and work is progressing on assembling the final wheel. This year has been a busy year for the installation of components in the EndCap C cryostat: the signal feedthrough installation was completed April 22nd, the pre-sampler shortly thereafter and the Electro-Magnetic EndCap August 13th. This allowed the HEC group to start transferring the HEC wheels from the T6A storage cradle into the cryostat. The operation started in mid-September and has progressed, on or ahead of schedule, since then with the major milestones being: Insertion of 67 ton front HEC wheel October 3rd Insertion of 90 ton rear HEC wheel October 22nd. The wheel alignment has proved to be excellent, with the position of the centre of the front(rear) wheel with respect to the nominal position being displaced b...

  18. $\\alpha$-Representation for QCD

    OpenAIRE

    Tuan, Richard Hong

    1998-01-01

    An $\\alpha$-parameter representation is derived for gauge field theories.It involves, relative to a scalar field theory, only constants and derivatives with respect to the $\\alpha$-parameters. Simple rules are given to obtain the $\\alpha$-representation for a Feynman graph with an arbitrary number of loops in gauge theories in the Feynman gauge.

  19. Alpha and conversion electron spectroscopy of 238,239Pu and 241Am and alpha-conversion electron coincidence measurements

    Energy Technology Data Exchange (ETDEWEB)

    Dion, Michael P.; Miller, Brian W.; Warren, Glen A.

    2016-09-01

    A technique to determine the isotopics of a mixed actinide sample has been proposed by measuring the coincidence of the alpha particle during radioactive decay with the conversion electron (or Auger) emitted during the relaxation of the daughter isotope. This presents a unique signature to allow the deconvolution of isotopes that possess overlapping alpha particle energy. The work presented here are results of conversion electron spectroscopy of 241Am, 238Pu and 239Pu using a dual-stage peltier-cooled 25 mm2 silicon drift detector. A passivated ion implanted planar silicon detector provided measurements of alpha spectroscopy. The conversion electron spectra were evaluated from 20–55 keV based on fits to the dominant conversion electron emissions, which allowed the relative conversion electron emission intensities to be determined. These measurements provide crucial singles spectral information to aid in the coincident measurement approach.

  20. Identification and functional characterization of the putative polysaccharide biosynthesis protein (CapD) of Enterococcus faecium U0317.

    Science.gov (United States)

    Ali, Liaqat; Spiess, Meike; Wobser, Dominique; Rodriguez, Marta; Blum, Hubert E; Sakιnç, Türkân

    2016-01-01

    Most bacterial species produce capsular polysaccharides that contribute to disease pathogenesis through evasion of the host innate immune system and are also involved in inhibiting leukocyte killing. In the present study, we identified a gene in Enterococcus faecium U0317 with homologies to the polysaccharide biosynthesis protein CapD that is made up of 336 amino acids and putatively catalyzes N-linked glycosylation. A capD deletion mutant was constructed and complemented by homologous recombination that was confirmed by PCR and sequencing. The mutant revealed different growth behavior and morphological changes compared to wild-type by scanning electron microscopy, also the capD mutant showed a strong hydrophobicity and that was reversed in the reconstituted mutant. For further characterization and functional analyses, in-vitro cell culture and in-vivo a mouse infection models were used. Antibodies directed against alpha lipotechoic acid (αLTA) and the peptidyl-prolyl cis-trans isomerase (αPpiC), effectively mediated the opsonophagocytic killing in the capD knock-out mutant, while this activity was not observed in the wild-type and reconstituted mutant. By comparison more than 2-fold decrease was seen in mutant colonization and adherence to both T24 and Caco2 cells. However, a significant higher bacterial colonization was observed in capD mutant during bacteremia in the animal model, while virulence in a mouse UTI (urinary tract infection) model, there were no obvious differences. Further studies are needed to elucidate the function of capsular polysaccharide synthesis gene clusters and its involvement in the disease pathogenesis with the aim to develop targeted therapies to treat multidrug-resistant E. faecium infections.