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Sample records for canitine maintains energy

  1. Dietary canitine maintains energy reserves and delays fatigue of exercised african catfish (Clarias gariepinus) fed high fat diets

    OpenAIRE

    Ozório Rodrigo; Van Ginneken Vincent; van den Thillart Guido; Verstegen Martin; Verreth Johan

    2005-01-01

    Lipids, together with proteins, are traditionally considered as primary fuels during aerobic swimming. The effects of dietary fat and carnitine supplements and exercise on the energy metabolism of juvenile fish were investigated. One hundred African catfish (Clarias gariepinus) were fed four isonitrogenous diets containing a fat level of 100 or 190 g kg-1 diet and one of the two levels of carnitine (15 and 1000 mg kg-1). Fish grew from 61 to 162 g in 10 wk. Thereafter, 6 fish per group swam v...

  2. Dietary canitine maintains energy reserves and delays fatigue of exercised african catfish (Clarias gariepinus) fed high fat diets Carnitina dietética mantem reservas energéticas e evita a fatiga de bagre-africano durante exercício

    OpenAIRE

    Rodrigo Ozório; Vincent Van Ginneken; Guido van den Thillart; Martin Verstegen; Johan Verreth

    2005-01-01

    Lipids, together with proteins, are traditionally considered as primary fuels during aerobic swimming. The effects of dietary fat and carnitine supplements and exercise on the energy metabolism of juvenile fish were investigated. One hundred African catfish (Clarias gariepinus) were fed four isonitrogenous diets containing a fat level of 100 or 190 g kg-1 diet and one of the two levels of carnitine (15 and 1000 mg kg-1). Fish grew from 61 to 162 g in 10 wk. Thereafter, 6 fish per group swam v...

  3. Dietary canitine maintains energy reserves and delays fatigue of exercised african catfish (Clarias gariepinus fed high fat diets Carnitina dietética mantem reservas energéticas e evita a fatiga de bagre-africano durante exercício

    Directory of Open Access Journals (Sweden)

    Rodrigo Ozório

    2005-06-01

    Full Text Available Lipids, together with proteins, are traditionally considered as primary fuels during aerobic swimming. The effects of dietary fat and carnitine supplements and exercise on the energy metabolism of juvenile fish were investigated. One hundred African catfish (Clarias gariepinus were fed four isonitrogenous diets containing a fat level of 100 or 190 g kg-1 diet and one of the two levels of carnitine (15 and 1000 mg kg-1. Fish grew from 61 to 162 g in 10 wk. Thereafter, 6 fish per group swam vigorously for 3 h and the results were compared with unexercised groups. Fish receiving 1,000 mg carnitine accumulated 2- to 3-fold more carnitine than fish receiving 15 mg carnitine. Plasma acyl-carnitine level was affected by an interaction between dietary treatment and exercise (P Lipídios e proteínas são tradicionalmente considerados combustíveis primários durante natação aeróbica. Nesse ensaio foi investigado o efeito da suplementação de vários níveis de gordura e carnitina no metabolismo de 100 bagres africanos juvenis (Clarias gariepinus. Os peixes foram arraçoados com quatro dietas isoprotéicas, cada uma contendo 100 ou 190 g gordura kg-1 dieta, e um dos dois níveis de carnitina (15 e 1000 mg kg-1. Os peixes cresceram de 61 a 162 g em 10 semanas. No final do ensaio de alimentação, grupos de seis peixes por tratamento foram induzidos a nadar vigorosamente por 3 h e em seguida vários parâmetros foram determinados no tecido muscular e plasma, e os resultados observados nos grupos exercitados foram comparados com grupos controles (não exercitados. Os peixes arraçoados com 1,000 mg carnitina acumularam de duas a três vezes mais carnitina que os peixes arraçoados com 15 mg carnitina. O nível de acyl-carnitina no plasma foi influenciado pela interação entre os tratamentos dietéticos e exercício físico (P < 0.05. As concentrações de adenosina trifosfato (ATP e fosfocreatina no tecido muscular branco (WM foram mais elevadas em

  4. Sociable Robots through Self-maintained Energy

    Directory of Open Access Journals (Sweden)

    Henrik Schioler

    2008-11-01

    Full Text Available Research of autonomous mobile robots has mostly emphasized interaction and coordination that are natually inspired from biological behavior of birds, insects, and fish: flocking, foraging, collecting, and sharing. However, most research has been only focused on autonomous behaviors in order to perform robots like animals, whereas it is lacked of determinant to those behaviours: energy. Approaching to clusted amimal and the higher, collective and sharing food among individuals are major activity to keep society being. This paper issues an approach to sociable robots using self-maintained energy in cooperative mobile robots, which is dominantly inspired from swarm behavior of collecting and sharing food of honey-bee and ant. Autonomous mobile robots are usually equipped with a finite energy, thus they can operate in a finite time. To overcome the finitude, we describe practical deployment of mobile robots that are capable of carrying and exchanging fuel to other robots. Mechanism implementation including modular hardware and control architecture to demonstrate the capabicities of the approach is presented. Subsequently, the battery exchange algorithm basically based on probabilistic modeling of total energy on each robot located in its local vicinity is described. The paper is concluded with challenging works of chain of mobile robots, rescue, repair, and relation of heterogeneous robots.

  5. Sociable Robots through Self-maintained Energy

    OpenAIRE

    Henrik Schioler; Trung Dung Ngo

    2006-01-01

    Research of autonomous mobile robots has mostly emphasized interaction and coordination that are natually inspired from biological behavior of birds, insects, and fish: flocking, foraging, collecting, and sharing. However, most research has been only focused on autonomous behaviors in order to perform robots like animals, whereas it is lacked of determinant to those behaviours: energy. Approaching to clusted amimal and the higher, collective and sharing food among individuals are major activi...

  6. Guide to Operating and Maintaining EnergySmart Schools

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-01-01

    Through a commitment to high performance, school districts are discovering that smart energy choices can create lasting benefits for students, communities, and the environment. For example, an energy efficient school district with 4,000 students can save as much as $160,000 a year in energy costs. Over 10 years, those savings can reach $1.6 million, translating into the ability to hire more teachers, purchase more textbooks and computers, or invest in additional high performance facilities. Beyond these bottomline benefits, schools can better foster student health, decrease absenteeism, and serve as centers of community life. The U.S. Department of Energy's EnergySmart Schools Program promotes a 30 percent improvement in existing school energy use. It also encourages the building of new schools that exceed code (ASHRAE 90.11999) by 50 percent or more. The program provides resources like this Guide to Operating and Maintaining EnergySmart Schools to assist school decisionmakers in planning, financing, operating, and maintaining energy efficient, high performance schools. It also offers education and training for building industry professionals. Operations and maintenance refer to all scheduled and unscheduled actions for preventing equipment failure or decline with the goal of increasing efficiency, reliability, and safety. A preventative maintenance program is the organized and planned performance of maintenance activities in order to prevent system or production problems or failures from occurring. In contrast, deferred maintenance or reactive maintenance (also called diagnostic or corrective maintenance) is conducted to address an existing problem. This guide is a primary resource for developing and implementing a districtor schoolwide operations and maintenance (O&M) program that focuses on energy efficiency. The EnergySmart Schools Solutions companion CD contains additional supporting information for design, renovation, and retrofit projects. The objective

  7. Sociable mobile robots through self-maintained energy

    DEFF Research Database (Denmark)

    Ngo, Trung Dung; Schiøler, Henrik

    2006-01-01

    society, collecting and sharing are experimentally recognized as the highest property. This paper issues an approach to sociable robots using self-maintained energy in robot society, which is naturally inspired from swarm behavior of honey-bee and ant. Typically, autonomous mobile robots are usually......Research of sociable robots has emphasized interaction and coordination of mobile robots with inspiration from natural behavior of birds, insects, and fish: flocking, foraging, collecting, sharing and so forth. However, the animal behaviors are looking for food towards survival. In an animal...... equipped with a finite energy, thus they can operate in a finite time. To overcome the limitation, we describe practical deployment of a group of mobile robot with the possibility of carrying and exchanging fuel, e.g. battery to other robots. Early implementation that includes modular hardware and control...

  8. Reliability, maintainability, and availability engineering for integrated community energy systems

    Energy Technology Data Exchange (ETDEWEB)

    Wang, P.Y.; Mavec, J.; Wolosewicz, R.M.; Calm, J.M.; Chopra, P.S.

    1979-12-01

    The reliability, maintainability, and availability (RMA) engineering methodologies for integrated community energy systems (ICES) are reported. Since the tangible and intangible costs of a system failure may outweigh the benefits of the ICES approaches, RMA consideration must be an integral part of ICES engineering. The effectiveness of system planning and design depends on component reliability information and on forecasts of community load profiles. Supply subsystems must provide sufficient capacity to meet demands in spite of maintenance and unscheduled outages. This allowance is the major task of probabilistic system planning. Because reliability and maintainability performance is partially a random process, probabilistic methodology is required for analysis and comparison. Portions of a community energy system being modified or expanded may already be in use before additional portions reach the design stage. This situation presents an opportunity to extend the RMA assessment of the existing system and to improve the additions that will be made to it. RMA engineering is essential to all phases of planning, design, construction, and operation of ICES. The methodologies presented provide a systematic, disciplined approach to predict and analyze RMA, to determine corrective actions necessary, and to achieve performance goals.

  9. Maintaining Department of Energy facilities general design criteria

    International Nuclear Information System (INIS)

    A General Design Criteria (GDC) Planning Board has been established in the Department of Energy to streamline the improvement and maintenance of the GDC Manual. This Planning Board, composed of a membership from field organizations and Headquarters programmatic offices, started work on 15 enhancements to the GDC Manual. One of those enhancements details natural phenomena hazards criteria. In the past year the Planning Board submitted a major recommendation which has been implemented into what is known as the GDC Improvements project. The result of this project pledges to dramatically increase the GDC Manual's utilization and effectiveness

  10. [Reduce Energy Costs While Maintaining Healthy IAQ.] "Indoor Air Quality Tools for Schools" Update #17

    Science.gov (United States)

    US Environmental Protection Agency, 2009

    2009-01-01

    This issue of "Indoor Air Quality Tools for Schools" Update ("IAQ TfS" Update) contains the following items: (1) News and Events; (2) Feature Article: Reduce Energy Costs while Maintaining Healthy IAQ; (3) Insight into Excellence: North East Independent School District ; (4) School Building Week 2009; and (5) Have Your Questions Answered!

  11. The role of international atomic energy agency in maintaining nuclear safety competence

    International Nuclear Information System (INIS)

    This paper provides information how International Atomic Energy Agency can assist Member States in maintaining and developing nuclear safety competence. The topics covered include the development of safety standards, organisation of nuclear safety related conferences, provision of safety reviews, organisation of training courses and topical workshops and publication of training related documents. Usefulness of these activities for competence development is discussed. (author)

  12. Energy usage while maintaining thermal comfort: A case study of a UNT dormitory

    Science.gov (United States)

    Gambrell, Dusten

    Campus dormitories for the University of North Texas house over 5500 students per year; each one of them requires certain comfortable living conditions while they live there. There is an inherit amount of money required in order to achieve minimal comfort levels; the cost is mostly natural gas for water and room heating and electricity for cooling, lighting and peripherals. The US Department of Energy has developed several programs to aid in performing energy simulations to help those interested design more cost effective building designs. Energy-10 is such a program that allows users to conduct whole house evaluations by reviewing and altering a few parameters such as building materials, solar heating, energy efficient windows etc. The idea of this project was to recreate a campus dormitory and try to emulate existent energy consumption then try to find ways of lowering that usage while maintaining a high level of personal comfort.

  13. The free energy cost of reducing noise while maintaining a high sensitivity

    CERN Document Server

    Sartori, Pablo

    2015-01-01

    Living systems need to be highly responsive, and also to keep fluctuations low. These goals are incompatible in equilibrium systems due to the Fluctuation Dissipation Theorem (FDT). Here, we show that biological sensory systems, driven far from equilibrium by free energy consumption, can reduce their intrinsic fluctuations while maintaining high responsiveness. By developing a continuum theory of the E. coli chemotaxis pathway, we demonstrate that adaptation can be understood as a non-equilibrium phase transition controlled by free energy dissipation, and it is characterized by a breaking of the FDT. We show that the maximum response at short time is enhanced by free energy dissipation. At the same time, the low frequency fluctuations and the adaptation error decrease with the free energy dissipation algebraically and exponentially, respectively.

  14. High protein diet maintains glucose production during exercise-induced energy deficit: a controlled trial

    Directory of Open Access Journals (Sweden)

    Castaneda-Sceppa Carmen

    2011-04-01

    Full Text Available Abstract Background Inadequate energy intake induces changes in endogenous glucose production (GP to preserve muscle mass. Whether addition provision of dietary protein modulates GP response to energy deficit is unclear. The objective was to determine whether exercise-induced energy deficit effects on glucose metabolism are mitigated by increased dietary protein. Methods Nineteen men ([mean ± SD] 23 ± 2 y, VO2peak 59 ± 5 ml·kg-1·min-1 were divided into three groups, two consuming moderate (MP; 0.9 g protein kg-1 d-1, and one high (HP; 1.8 g protein kg-1 d-1 protein diets (55% energy from carbohydrate for 11 days. Following 4 days of energy balance (D1-4, energy expenditure was increased for 7 days (D5-12 in all groups. Energy intake was unchanged in two, creating a 1000 kcal d-1 deficit (DEF-MP, DEF-HP; n = 6, both groups, whereas energy balance was maintained in the third (BAL-MP, n = 7. Biochemical markers of substrate metabolism were measured during fasting rest on D4 and D12, as were GP and contribution of gluconeogenesis to endogenous glucose production (fgng using 4-h primed, continuous infusions of [6,6-2H2]glucose (dilution-method and [2-13C]glycerol (MIDA technique. Glycogen breakdown (GB was derived from GP and fgng. Results Plasma β-hydroxybutyrate levels increased, and plasma glucose and insulin declined from D4 to D12, regardless of group. DEF-MP experienced decreased plasma GP from D4 to D12 ([mean change ± SD] 0.24 ± 0.24 mg·kg-1·min-1, due to reduced GB from D4 (1.40 ± 0.28 mg·kg-1·min-1 to D12 (1.16 ± 0.17 mg·kg-1·min-1, P -1·min-1, respectively by maintaining GB. Conclusion Exercise-induced energy deficit decreased GP and additional dietary protein mitigated that effect.

  15. Research on Utilizing a Multivariate Feedback Algorithm to Maintain Stable Operation of Variable Energy Electron Accelerators

    International Nuclear Information System (INIS)

    Measurements performed utilizing particle accelerators rely on the stability and reproducibility of the accelerator operation, most notably for beam flux (beam current) and beam energy. This can be vital when the measurements rely on previous calibrations performed to establish a standard on which to base the end result of the measurement. The authors have designed a monitoring and control virtual instrument (VI) based on National Instruments LabVIEWTM which calls external modeling code that is written in a standard programming language. The LabVIEWTM virtual instrument allows the user to monitor multiple accelerator parameters while permitting user control of the most important four of these parameters which determine machine operation. The external modeling code, the Advanced Data Validation and Verification System (ADVVS), incorporates as a kernel the Universal Process Model (UPM) software from Triant Technologies, Inc. The kernel executes the accelerator modeling function based on previously acquired history data of the relevant parameters for accelerator operation for conditions of interest. This history data is stored as a reference set prior to subsequent operation. During accelerator operation, 11 accelerator parameters are input to ADVVS from the LabVIEWTM virtual instrument. The ADVVS uses the reference files to predict the eleven parameter values that would normally be expected for optimal accelerator operation. The set of 11 model values is the nearest model state. This multivariate modeling approach presented two principal advantages: 1. The ADVVS allowed rapid detection of anomalous accelerator behavior variant from normal accelerator behavior recorded in the reference set of the kernel. 2. The ADVVS presented a methodology to incrementally tune the accelerator back to optimal operation, thus maintaining highly stable and reproducible operation. In the future, this methodology may also be utilized to tune the accelerator initially or move efficiently

  16. Human factors design guidelines for maintainability of Department of Energy nuclear facilities

    International Nuclear Information System (INIS)

    Intent of these guidelines is to provide design and design review teams of DOE nuclear facilities with human factors principles to enhance the design and aid in the inspection of DOE nuclear facilities, systems, and equipment. These guidelines are concerned with design features of DOE nuclear facilities which can potentially affect preventive and corrective maintenance of systems within DOE nuclear facilities. Maintenance includes inspecting, checking, troubleshooting, adjusting, replacing, repairing, and servicing activities. Other factors which influence maintainability such as repair and maintenance suport facilities, maintenance information, and various aspects of the environment are also addressed

  17. Human factors design guidelines for maintainability of Department of Energy nuclear facilities

    Energy Technology Data Exchange (ETDEWEB)

    Bongarra, J.P. Jr.; VanCott, H.P.; Pain, R.F.; Peterson, L.R.; Wallace, R.I.

    1985-06-18

    Intent of these guidelines is to provide design and design review teams of DOE nuclear facilities with human factors principles to enhance the design and aid in the inspection of DOE nuclear facilities, systems, and equipment. These guidelines are concerned with design features of DOE nuclear facilities which can potentially affect preventive and corrective maintenance of systems within DOE nuclear facilities. Maintenance includes inspecting, checking, troubleshooting, adjusting, replacing, repairing, and servicing activities. Other factors which influence maintainability such as repair and maintenance suport facilities, maintenance information, and various aspects of the environment are also addressed.

  18. Strip intercropping strategy for biomass to energy production while on the same time maintaining soil fertility

    DEFF Research Database (Denmark)

    Hauggard-Nielsen, Henrik; Jensen, Erik Steen; Carter, Mette Sustmann; Johansen, Anders; Ambus, Per

    2009-01-01

    In contrast to energy technologies like solar and wind, energy in the form of biomass can be stored and bioenergy produced when needed using a wide range of technologies. However, a substantial rise in the use of biomass for energy is expected, which means additional pressure on farmland sustaina...... enhance soil fertility, extract nutrients form deeper soil layers, fix N2 and compensate for the effect of annual crops on soil fertility?...

  19. Planning Machine Activity Between Manufacturing Operations: Maintaining Accuracy While Reducing Energy Consumption

    OpenAIRE

    Parkinson, Simon; Vallati, Mauro; Chrpa, Lukáš; Longstaff, Andrew P.; Fletcher, Simon

    2016-01-01

    There has recently been an increased emphasis on reducing energy consumption in manufacturing. This is largely because of fluctuations in energy costs causing uncertainty. The increased competition between manufacturers means that even a slight change in energy consumption can have implications on their profit margin or competitiveness of quote. Furthermore, there is a drive from policy-makers to audit the environmental impact of manufactured goods from cradle-to-grave. The understanding, and...

  20. Plasma Treatment Maintains Surface Energy of the Implant Surface and Enhances Osseointegration

    OpenAIRE

    Guastaldi, Fernando P. S.; Daniel Yoo; Charles Marin; Ryo Jimbo; Nick Tovar; Darceny Zanetta-Barbosa; Coelho, Paulo G

    2013-01-01

    The surface energy of the implant surface has an impact on osseointegration. In this study, 2 surfaces: nonwashed resorbable blasting media (NWRBM; control) and Ar-based nonthermal plasma 30 days (Plasma 30 days; experimental), were investigated with a focus on the surface energy. The surface energy was characterized by the Owens-Wendt-Rabel-Kaelble method and the chemistry by X-ray photoelectron spectroscopy (XPS). Five adult beagle dogs received 8 implants (n = 2 per surface, per tibia). Af...

  1. Polarization Maintaining, Very-Large-Mode Area, Er Fiber Amplifier for High Energy Pulses at 1572.3 nm

    Science.gov (United States)

    Nicholoson, J. W.; DeSantolo, A.; Yan, M. F.; Wisk, P.; Mangan, B.; Puc, G.; Yu, A.; Stephen, M.

    2016-01-01

    We demonstrate the first polarization maintaining, very-large-mode-area Er-doped fiber amplifier with 1000 square micron effective area. The amplifier is core pumped by a Raman fiber laser and is used to generate single frequency one microsecond pulses with pulse energy of 368 microJoules, M2 of 1.1, and polarization extinction greater than 20 dB. The amplifier operates at 1572.3 nm, a wavelength useful for trace atmospheric CO2 detection.

  2. Nuts Improve Diet Quality Compared to Other Energy-Dense Snacks While Maintaining Body Weight

    OpenAIRE

    Conor Delahunty; Andrew Gray; Alexandra Chisholm; Siew Ling Tey; Rachel Brown

    2011-01-01

    Previous studies have reported that regular nut consumption reduces cardiovascular disease (CVD) risk and does not promote weight gain despite the fact that nuts are energy-dense. However, no studies have investigated the body composition of those regularly consuming nuts compared to similar intakes of other snacks of equal energy density. This parallel study (n = 118) examined the effects of providing daily portions (~1100 kJ/d) of hazelnuts, chocolate, or potato crisps compared to a control...

  3. Switchgrass for energy in Southern Iowa: developing and maintaining producer involvement

    International Nuclear Information System (INIS)

    A major objective of the Chariton Valley Resource Conservation and Development (RC and D) Area in southern Iowa is to create markets based on locally sustainable resources to increase rural incomes and job opportunities. Perennial forages and grasslands are compatible with the area's soil resources, but they have limited markets. In Chariton Valley, establishing a market for biomass as an energy crop is attractive to local producers, but doing so is complicated by a variety of economic and environmental issues. Organizing, assisting and actively involving potential biomass producers at the local level is an integral part of developing an energy crop industry. Producer involvement is key in field level production research. This involvement leads to a better understanding of the value of biomass crops. Producer-led demonstrations of harvest and handling creates confidence that agriculture can serve effectively as an energy supplier. Producers also provide an important political constituency that support public policy changes needed to more accurately value the environmental and rural development benefits of energy crops. (author)

  4. OECD nuclear energy agency role in promoting and maintaining nuclear safety research

    Energy Technology Data Exchange (ETDEWEB)

    Reig, J. [OECD Nuclear Energy Agency (France)

    2004-07-01

    The paper describes the activities of the safety committees of the OECD Nuclear Energy Agency. The committee on the safety of nuclear installations (CSNI), promotes the exchange of safety relevant information and develops common understanding and approaches on current safety issues. One of the unique features of NEA is to organise safety research activities, and in particular to promote joint OECD/NEA research projects. During its forty years of work, NEA safety committees have contributed to address safety challenges and to look for common approaches to regulatory practices and criteria. (orig.)

  5. OECD nuclear energy agency role in promoting and maintaining nuclear safety research

    International Nuclear Information System (INIS)

    The paper describes the activities of the safety committees of the OECD Nuclear Energy Agency. The committee on the safety of nuclear installations (CSNI), promotes the exchange of safety relevant information and develops common understanding and approaches on current safety issues. One of the unique features of NEA is to organise safety research activities, and in particular to promote joint OECD/NEA research projects. During its forty years of work, NEA safety committees have contributed to address safety challenges and to look for common approaches to regulatory practices and criteria. (orig.)

  6. Decision regarding Gazifere Inc.'s request to maintain current tariffs, its distribution plan and energy efficiency plan

    International Nuclear Information System (INIS)

    In June 2002 Gazifere Inc. applied to Quebec's Regie de l'energie for approval to maintain its current gas tariffs in its area of operation, the Outaouais region of Quebec. Gazifere also presented its program for energy efficiency and its distribution program with a request to extend its distribution network in the Outaouais. The energy efficiency program includes the rental of residential water heaters, water and gas savings, high efficiency furnaces, rental of commercial water heaters, and a program for low income families. The Regie reviewed the application and declared that the current fees could remain in effect until October 1, 2002. It also approved the modifications proposed by Gazifere to the adjustment of rates. The Regie reviewed the objectives of the energy efficiency programs and approved a volumetric budget for the plan and authorized that the deferred rate be kept in the energy efficiency program. The Regie approved that the energy efficiency plan should extend over 3 years with the exception of the residential inspection program until more information could be gathered on the energy savings in the residential sector. The Regie made a request to Gazifere to provide data on industrial consumption before authorizing $3,730,200 for extension of their distribution network. It approved the amount $5,306,400 as exploitation charges for the year 2002-2003. refs., tabs

  7. Cyber-physical system for a water reclamation plant: Balancing aeration, energy, and water quality to maintain process resilience

    Science.gov (United States)

    Zhu, Junjie

    Aeration accounts for a large fraction of energy consumption in conventional water reclamation plants (WRPs). Although process operations at older WRPs can satisfy effluent permit requirements, they typically operate with excess aeration. More effective process controls at older WRPs can be challenging as operators work to balance higher energy costs and more stringent effluent limitations while managing fluctuating loads. Therefore, understandings of process resilience or ability to quickly return to original operation conditions at a WRP are important. A state-of-art WRP should maintain process resilience to deal with different kinds of perturbations even after optimization of energy demands. This work was to evaluate the applicability and feasibility of cyber-physical system (CPS) for improving operation at Metropolitan Water Reclamation District of Greater Chicago (MWRDGC) Calumet WRP. In this work, a process model was developed and used to better understand the conditions of current Calumet WRP, with additional valuable information from two dissolved oxygen field measurements. Meanwhile, a classification system was developed to reveal the pattern of historical influent scenario based on cluster analysis and cross-tabulation analysis. Based on the results from the classification, typical process control options were investigated. To ensure the feasibility of information acquisition, the reliability and flexibility of soft sensors were assessed to typical influent conditions. Finally, the process resilience was investigated to better balance influent perturbations, energy demands, and effluent quality for long-term operations. These investigations and evaluations show that although the energy demands change as the influent conditions and process controls. In general, aeration savings could be up to 50% from the level of current consumption; with a more complex process controls, the saving could be up to 70% in relatively steady-state conditions and at least 40

  8. Challenges in Maintaining Emotion Regulation in a Sleep and Energy Deprived State Induced by the 4800Km Ultra-Endurance Bicycle Race; The Race Across AMerica (RAAM)

    Science.gov (United States)

    Lahart, Ian M.; Lane, Andrew M.; Hulton, Andrew; Williams, Karen; Godfrey, Richard; Pedlar, Charles; Wilson, Mathew G.; Whyte, Gregory P.

    2013-01-01

    Multiday ultra-endurance races present athletes with a significant number of physiological and psychological challenges. We examined emotions, the perceived functionality (optimal-dysfunctional) of emotions, strategies to regulate emotions, sleep quality, and energy intake-expenditure in a four-man team participating in the Race Across AMerica (RAAM); a 4856km continuous cycle race. Cyclists reported experiencing an optimal emotional state for less than 50% of total competition, with emotional states differing significantly between each cyclist over time. Coupled with this emotional disturbance, each cyclist experienced progressively worsening sleep deprivation and daily negative energy balances throughout the RAAM. Cyclists managed less than one hour of continuous sleep per sleep episode, high sleep latency and high percentage moving time. Of note, actual sleep and sleep efficiency were better maintained during longer rest periods, highlighting the importance of a race strategy that seeks to optimise the balance between average cycling velocity and sleep time. Our data suggests that future RAAM cyclists and crew should: 1) identify beliefs on the perceived functionality of emotions in relation to best (functional-optimal) and worst (dysfunctional) performance as the starting point to intervention work; 2) create a plan for support sufficient sleep and recovery; 3) create nutritional strategies that maintain energy intake and thus reduce energy deficits; and 4) prepare for the deleterious effects of sleep deprivation so that they are able to appropriately respond to unexpected stressors and foster functional working interpersonal relationships. Key Points Completing the Race Across AMerica (RAAM); a 4856km continuous cycle race associated with sleep disturbance, an energy-deficient state, and experiencing intense unwanted emotions. Cyclists reported experiencing an optimal emotional state for less than 50% of total competition and actual sleep and sleep efficiency

  9. Paradoxes of western energy development: how can we maintain the land and the people if we develop

    Energy Technology Data Exchange (ETDEWEB)

    McKell, C.M.; Browne, D.G.; Cruze, E.C.; Freudenburg, W.R.; Perrine, R.L.; Roach, F. (eds.)

    1984-01-01

    The 27 authors of this book evaluate western energy resources, then discuss the consequences of development on the region's physical and social environments. Among the questions they consider are the distribution of environmental costs and economic benefits of development; the effects on the environment, the social structure, and the quality of life; whether open spaces should be regarded as a national treasure in their present form or as space available for development; the unique demands of reclamation in the arid west; and the impact of new federal and state policies on resource management, given the recent trend of western states-rights militancy and population shifts to the southwest. Separate abstracts were prepared for 12 papers selected for the Energy Data Base (EDB) and Energy Abstracts for Policy Analysis (EAPA). Two papers were processed earlier.

  10. CHALLENGES IN MAINTAINING EMOTION REGULATION IN A SLEEP AND ENERGY DEPRIVED STATE INDUCED BY THE 4800KM ULTRA-ENDURANCE BICYCLE RACE; THE RACE ACROSS AMERICA (RAAM

    Directory of Open Access Journals (Sweden)

    Ian M. Lahart

    2013-09-01

    Full Text Available Multiday ultra-endurance races present athletes with a significant number of physiological and psychological challenges. We examined emotions, the perceived functionality (optimal-dysfunctional of emotions, strategies to regulate emotions, sleep quality, and energy intake-expenditure in a four-man team participating in the Race Across AMerica (RAAM; a 4856km continuous cycle race. Cyclists reported experiencing an optimal emotional state for less than 50% of total competition, with emotional states differing significantly between each cyclist over time. Coupled with this emotional disturbance, each cyclist experienced progressively worsening sleep deprivation and daily negative energy balances throughout the RAAM. Cyclists managed less than one hour of continuous sleep per sleep episode, high sleep latency and high percentage moving time. Of note, actual sleep and sleep efficiency were better maintained during longer rest periods, highlighting the importance of a race strategy that seeks to optimise the balance between average cycling velocity and sleep time. Our data suggests that future RAAM cyclists and crew should: 1 identify beliefs on the perceived functionality of emotions in relation to best (functional-optimal and worst (dysfunctional performance as the starting point to intervention work; 2 create a plan for support sufficient sleep and recovery; 3 create nutritional strategies that maintain energy intake and thus reduce energy deficits; and 4 prepare for the deleterious effects of sleep deprivation so that they are able to appropriately respond to unexpected stressors and foster functional working interpersonal relationships

  11. Dietary Carnitine maintains energy reserves and delays fatigue of exercised African catfish (Clarias Gariepinus) fed high fat diets

    OpenAIRE

    Ozorio, R.; Ginneken, van, CJJM Kees; Thillart, van den, G.; M.W.A. Verstegen; Verreth, J.A.J.

    2005-01-01

    Lipids, together with proteins, are traditionally considered as primary fuels during aerobic swimming. The effects of dietary fat and carnitine supplements and exercise on the energy metabolism of juvenile fish were investigated. One hundred African catfish (Clarias gariepinus) were fed four isonitrogenous diets containing a fat level of 100 or 190 g kg-1 diet and one of the two levels of carnitine (15 and 1000 mg kg-1). Fish grew from 61 to 162 g in 10 wk. Thereafter, 6 fish per group swam v...

  12. High energy, 1572.3 nm pulses for CO2 LIDAR from a polarization-maintaining, very-large-mode-area, Er-doped fiber amplifier.

    Science.gov (United States)

    Nicholson, J W; DeSantolo, A; Yan, M F; Wisk, P; Mangan, B; Puc, G; Yu, A W; Stephen, M A

    2016-08-22

    We demonstrate the first polarization-maintaining, very-large-mode-area, Er-doped fiber amplifier with ~1100 μm2 effective area. The amplifier is core pumped by a Raman fiber laser and is used to generate single-frequency, one-microsecond, pulses with pulse energy of 541 μJ, peak power of 700 W, M2 of 1.1, and polarization extinction > 20 dB. The amplifier operates at 1572.3 nm, a wavelength useful for trace atmospheric CO2 detection. PMID:27557271

  13. Energy Behavior in Ad Hoc Network Minimizing the Number of Hops and Maintaining Connectivity of Mobile Terminals Which Move from One to the Others

    Directory of Open Access Journals (Sweden)

    Kohei Arai, Lipur Sugiyanta

    2011-08-01

    Full Text Available Wireless ad-hoc network is a special kind of network, where all of the nodesmove in time. The topology of the network changes as the nodes are in theproximity of each other. Ad-hoc networks are generally self-configuring no stableinfrastructure takes a place. In this network, each node should help relayingpackets of neighboring nodes using multi-hop routing mechanism. Thismechanism is needed to reach far destination nodes to solve problem of deadcommunication. This multiple traffic hops within a wireless ad-hoc networkcaused dilemma. Wireless ad-hoc network that contain multiple hops becomeincreasingly vulnerable to problems such as energy degradation and rapidincreasing of overhead packets. This paper provides a generic routing frameworkthat balances energy efficient broadcast schemes in Wireless Ad-Hoc Networkand maintaining connectivity of nodes (mobile terminals. Typically, each node’sactivities will consume energy, either for sending packets, receiving orpreparing/processing packets. Number of hops, distance of nodes, and size ofpacket will determine the consumption of energy. The framework is based on theprinciple that additional relay nodes with appropriate energy and routing metricbetween source and final destination significantly reduces the energyconsumption necessary to deliver packets in Wireless Ad-Hoc Network whilekeep the connectivity of dynamic nodes. Using the framework, the averagenetwork connectivity is kept 18% higher and the lifetime of network lasting morethan 2.38% compared with network with Link State Routing mechanism. Thesimulation notes that the end-to-end delay may increase rapidly if relay nodesare more than five.

  14. Model Experiment Study on Maintaining Stability of Frozen Subgrade by Collecting-Controlling Cold Energy%采控冷量维护冻土路基稳定的模拟试验研究

    Institute of Scientific and Technical Information of China (English)

    刘志强; 周国庆; 马巍; 牛富俊; 别小勇

    2004-01-01

    The stability of railway subgrade in permafrost regions is crucial to the safety of railway operation. In this paper, we first analyze the main factors influencing the stability of frozen subgrade. Then,we build an experimental equipment in which regulation-tubes are arranged axially in subgrade and arranged slantways at the foot of slopes, and make the model experiments on maintaining the stability of frozen subgrade by collecting- controlling cold energy. The experiments include two groups. One is maintaining the stability by collecting-controlling natural cold energy in winter, and another is maintaining the stability by collecting-controliing natural cold energy in winter and artificial cold energy in summer. Finally, we obtain the behavior of temperature fields in the subgrade during the experiments,which establishes basis for further study on the subgrade stability and on the feasibility of rushing to deal with freezing damage of frozen subgrade.

  15. Maintaining Learners’Motivation

    Institute of Scientific and Technical Information of China (English)

    SI Zi-han

    2015-01-01

    Foreign language learning is a complex process and its success is determined by a variety of factors. The prime one of them is motivation ,which, as everyone knows, could be controlled by external forces so as to be taken advantage of. Motivation could prompt the learner to have his own learning goals and let him finish his learning task autonomously. All of that shows the im⁃portance of maintaining learners’motivation. This paper will demonstrate not only the definition and the types of motivation, but al⁃so the methods that could be used to stimulate and maintain the motivation.

  16. Maintaining Your Health

    Science.gov (United States)

    ... center but can also be done in nursing facilities, hospitals, or at home. Book a PFF Ambassador for your event. Call 844.TalkPFF > Life with PF About PF Treatment Options Clinical Trials Maintaining Your Health Find Medical Care Support Groups PFF ...

  17. Maintaining dignity in vulnerability

    DEFF Research Database (Denmark)

    Høy, Bente

    2015-01-01

    Background. Older people, living in nursing homes, are exposed to diverse situations, which may be associated with loss of dignity. To help them maintain their dignity, it is important to explore, how dignity is preserved in such context. Views of dignity and factors influencing dignity have been...... studied from both the residents´ and the care pro-viders´ perspective. However, most of these studies pertain to experiences in the dying or the illness context. Knowledge is scarce about how older people experience their dig-nity within their everyday lives in nursing homes. Aim To illuminate the meaning...... of maintaining dignity from the perspective of older people living in nursing homes Method. This qualitative study is based on individual interviews. Twenty-eight nursing home residents were included from six nursing homes in Scandinavia. A phenomenolog-ical-hermeneutic approach, inspired by Ricoeur...

  18. Maintaining Relationship Based Procurement

    Directory of Open Access Journals (Sweden)

    Peter Davis

    2012-11-01

    Full Text Available Alliance and relationship projects are increasingin number and represent a large pool of work. Tobe successful relationship style contracts dependon soft-dollar factors, particularly the participants'ability to work together within an agreedframework, generally they are not based on lowbid tendering. Participants should be prepared todo business in an open environment based ontrust and mutually agreed governance. Theresearch evaluates relationship maintenance inthe implementation phase of constructionalliances - a particular derivative of relationshipstyle contracts. To determine the factors thatcontribute to relationship maintenance forty-nineexperienced Australian alliance projectmanagers were interviewed. The main findingswere; the development of relationships early inthe project form building blocks of success fromwhich relationships are maintained and projectvalue added; quality facilitation plays animportant part in relationship maintenance and ahybrid organisation created as a result of alliancedevelopment overcomes destructiveorganisational boundaries. Relationshipmaintenance is integral to alliance project controland failure to formalise it and pay attention toprocess and past outcomes will undermine analliance project's potential for success.

  19. Building and maintaining media contacts

    International Nuclear Information System (INIS)

    This presentation is answering the question: 'how does British Energy build and maintain its relationships with journalists in so many areas', not only the basic industrial correspondents that you would expect to have to deal with an industry British Energy, but those dealing with science and technology, the environment, personnel and training, city and financial, political, and on and on, and that is just the national press. Then add the local and regional media around power station sites - literally hundreds of contacts and you start to get an idea about the size of our media contact database. But it is managed it rather well. Every six months British Energy takes part in a survey run by one of the UK's leading market research companies who conducts a poll among journalists and then rate each company's performance. In the last three years British Energy has not been outside the top five in most categories, and in the top two in several. The answer is a lot of work over a long period of time. You cannot expect to build trusting relationships with a journalist overnight. At British Energy the key is being open and honest, and always available. Of course good media relations is not a one-way street, and there has to be some element of compromise if you are to achieve a relationship based on mutual trust

  20. ADAS Update and Maintainability

    Science.gov (United States)

    Watson, Leela R.

    2010-01-01

    Since 2000, both the National Weather Service Melbourne (NWS MLB) and the Spaceflight Meteorology Group (SMG) have used a local data integration system (LOIS) as part of their forecast and warning operations. The original LOIS was developed by the Applied Meteorology Unit (AMU) in 1998 (Manobianco and Case 1998) and has undergone subsequent improvements. Each has benefited from three-dimensional (3-D) analyses that are delivered to forecasters every 15 minutes across the peninsula of Florida. The intent is to generate products that enhance short-range weather forecasts issued in support of NWS MLB and SMG operational requirements within East Central Florida. The current LDIS uses the Advanced Regional Prediction System (ARPS) Data Analysis System (AD AS) package as its core, which integrates a wide variety of national, regional, and local observational data sets. It assimilates all available real-time data within its domain and is run at a finer spatial and temporal resolution than current national or regional-scale analysis packages. As such, it provides local forecasters with a more comprehensive understanding of evolving fine-scale weather features. Over the years, the LDIS has become problematic to maintain since it depends on AMU-developed shell scripts that were written for an earlier version of the ADAS software. The goals of this task were to update the NWS MLB/SMG LDIS with the latest version of ADAS, incorporate new sources of observational data, and upgrade and modify the AMU-developed shell scripts written to govern the system. In addition, the previously developed ADAS graphical user interface (GUI) was updated. Operationally, these upgrades will result in more accurate depictions of the current local environment to help with short-range weather forecasting applications, while also offering an improved initialization for local versions of the Weather Research and Forecasting (WRF) model used by both groups.

  1. Maintaining Web Cache Coherency

    Directory of Open Access Journals (Sweden)

    2000-01-01

    Full Text Available Document coherency is a challenging problem for Web caching. Once the documents are cached throughout the Internet, it is often difficult to keep them coherent with the origin document without generating a new traffic that could increase the traffic on the international backbone and overload the popular servers. Several solutions have been proposed to solve this problem, among them two categories have been widely discussed: the strong document coherency and the weak document coherency. The cost and the efficiency of the two categories are still a controversial issue, while in some studies the strong coherency is far too expensive to be used in the Web context, in other studies it could be maintained at a low cost. The accuracy of these analysis is depending very much on how the document updating process is approximated. In this study, we compare some of the coherence methods proposed for Web caching. Among other points, we study the side effects of these methods on the Internet traffic. The ultimate goal is to study the cache behavior under several conditions, which will cover some of the factors that play an important role in the Web cache performance evaluation and quantify their impact on the simulation accuracy. The results presented in this study show indeed some differences in the outcome of the simulation of a Web cache depending on the workload being used, and the probability distribution used to approximate updates on the cached documents. Each experiment shows two case studies that outline the impact of the considered parameter on the performance of the cache.

  2. Four weeks of speed endurance training reduces energy expenditure during exercise and maintains muscle oxidative capacity despite a reduction in training volume

    DEFF Research Database (Denmark)

    Iaia, F. Marcello; Hellsten, Ylva; Nielsen, Jens Jung; Fernström, Maria; Sahlin, Kent; Bangsbo, Jens

    2009-01-01

    We studied the effect of an alteration from regular endurance to speed endurance training on muscle oxidative capacity, capillarization, as well as energy expenditure during submaximal exercise and its relationship to mitochondrial uncoupling protein 3 (UCP3) in humans. Seventeen endurance-trained...... runners were assigned to either a speed endurance training (SET; n = 9) or a control (Con; n = 8) group. For a 4-wk intervention (IT) period, SET replaced the ordinary training ( approximately 45 km/wk) with frequent high-intensity sessions each consisting of 8-12 30-s sprint runs separated by 3 min of...... rest (5.7 +/- 0.1 km/wk) with additional 9.9 +/- 0.3 km/wk at low running speed, whereas Con continued the endurance training. After the IT period, oxygen uptake was 6.6, 7.6, 5.7, and 6.4% lower (P < 0.05) at running speeds of 11, 13, 14.5, and 16 km/h, respectively, in SET, whereas remained the same...

  3. AECL's reliability and maintainability program

    International Nuclear Information System (INIS)

    AECL's reliability and maintainability program for nuclear generating stations is described. How the various resources of the company are organized to design and construct stations that operate reliably and safely is shown. Reliability and maintainability includes not only special mathematically oriented techniques, but also the technical skills and organizational abilities of the company. (author)

  4. Marshal: Maintaining Evolving Models Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SIFT proposes to design and develop the Marshal system, a mixed-initiative tool for maintaining task models over the course of evolving missions. Marshal-enabled...

  5. A Novel Polarization Maintaining Fiber

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    It introduces a novel elliptical jacket polarization maintaining fiber, whose SAP is like numeral "1". One preform can be drawn over 8km. Fiber's performances show that it is fit for fiber gyroscope and other sensors.

  6. A Novel Polarization Maintaining Fiber

    Institute of Scientific and Technical Information of China (English)

    Benjamin Xue

    2003-01-01

    It introduces a novel elliptical jacket polarization maintaining fiber, whose SAP is like numeral "1" One preform can be drawn over 8km. Fiber's performances show that it is fit for fiber gyroscope and other sensors.

  7. Efficient And Maintainable Test Automation

    OpenAIRE

    Ahmed, Abdifatah; Lindhe, Magnus

    2002-01-01

    More and more companies experience problems with maintainability and time-consuming development of automated testing tools. The MPC department at Ericsson Software Technology AB use methods and tools often developed during time pressure that results in time-consuming testing and requires more effort and resources than planned. The tools are also such nature that they are hard to expand, maintain and in some cases they have been thrown out between releases. For this reason, we could identify t...

  8. Maintaining qualification for 340B.

    Science.gov (United States)

    Gricius, Robert F; Wong, Douglas

    2016-03-01

    After initial acceptance in the 340B Drug Pricing Program, hospitals and health systems should monitor and take steps to maintain their disproportionate share hospital status to continue to qualify for participation. Proactively managing the Supplemental Security Income (SSI) Ratio will ensure the organization avoids an unexpected decline in the Medicare portion of its 340B patient base. Even with the surge resulting from Medicaid expansion, tracking patient eligibility for Medicare/ SSI to ensure all patients who qualify are appropriately enrolled in the program is an important step in maintaining 340B program eligibility. PMID:27183761

  9. Maintaining Sustainability for Green Schools

    Science.gov (United States)

    Kennedy, Mike

    2011-01-01

    The promise of sustainably designed school facilities is that they will operate more efficiently and last longer than buildings constructed in more traditional ways. But that promise comes with a big if. The payoff is delivered only if the facility managers operate and maintain the buildings in ways that adhere to sustainable strategies called for…

  10. Developing and maintaining nuclear competencies

    International Nuclear Information System (INIS)

    The paper discusses the following aspects on the nuclear knowledge management: assimilation of knowledge management, recognition of the nuclear specificity, attracting young talents. Another feature which, possibly, differentiates nuclear from other high-tech industries is that time constraints in some nuclear development may very well exceed the duration of a generation of professionals. That means, not only maintaining scientific and technical knowledge, which, as a minimum, leads to maintain: a rigorous supervision of human resources in quality and quantity; anticipatory planning of human resources, with a special focus on succession planning concerning expertise positions; a steady and continuous effort in training and retraining programs. Maintaining the safety culture is also one of the major managerial duties. Taking full account of the nuclear specificity in knowledge maintenance and development in the AREVA group, requests a multifunctional approach, which combines efforts of Research and Innovation, and Human Resources departments, plus the group Nuclear inspectorate. It is acknowledged that the industry, basically, would readily rely on the capabilities of the academic world and research centers in ensuring that training and education in nuclear science and technologies are attuned to the evolving needs of the industry, in maintaining the proper educational programs and in fostering fruitful cooperations between them

  11. Strategies for Maintaining Community Integration.

    Science.gov (United States)

    Gruber, Fred

    1986-01-01

    This article outlines strategies of maintaining integration emphasizing: (1) housing offices and counseling; (2) community action to alter real estate policies; (3) school action including public relations and human relations thinking; (4) community organization of commercial and religious institutions; (5) financial incentives for pro-integrative…

  12. Bulkloading and Maintaining XML Documents

    NARCIS (Netherlands)

    Schmidt, A.R.; Kersten, M.L.

    2002-01-01

    The popularity of XML as a exchange and storage format brings about massive amounts of documents to be stored, maintained and analyzed -- a challenge that traditionally has been tackled with Database Management Systems (DBMS). To open up the content of XML documents to analysis with declarative quer

  13. Control Inflation while Maintain Growth

    Institute of Scientific and Technical Information of China (English)

    Yang Junsheng

    2008-01-01

    @@ Dragged by the U.S.subprime crisis and the soaring oil price, the global economy is slowing down,causing problems to China, the country which has continuously achieved miraculous economic growth.Apart from the accumulation of high inflation and risks of overheated economy, China is attacked by serious natural disasters ever since the beginning of 2008,including the snow disaster, the earthquake and the flood.It is obviously that China's priority now is to bring inflation under control so as to maintain the stable growth of economy.

  14. Drosophila larvae lacking the bcl-2 gene, buffy, are sensitive to nutrient stress, maintain increased basal target of rapamycin (Tor signaling and exhibit characteristics of altered basal energy metabolism

    Directory of Open Access Journals (Sweden)

    Monserrate Jessica P

    2012-07-01

    Full Text Available Abstract Background B cell lymphoma 2 (Bcl-2 proteins are the central regulators of apoptosis. The two bcl-2 genes in Drosophila modulate the response to stress-induced cell death, but not developmental cell death. Because null mutants are viable, Drosophila provides an optimum model system to investigate alternate functions of Bcl-2 proteins. In this report, we explore the role of one bcl-2 gene in nutrient stress responses. Results We report that starvation of Drosophila larvae lacking the bcl-2 gene, buffy, decreases survival rate by more than twofold relative to wild-type larvae. The buffy null mutant reacted to starvation with the expected responses such as inhibition of target of rapamycin (Tor signaling, autophagy initiation and mobilization of stored lipids. However, the autophagic response to starvation initiated faster in larvae lacking buffy and was inhibited by ectopic buffy. We demonstrate that unusually high basal Tor signaling, indicated by more phosphorylated S6K, was detected in the buffy mutant and that removal of a genomic copy of S6K, but not inactivation of Tor by rapamycin, reverted the precocious autophagy phenotype. Instead, Tor inactivation also required loss of a positive nutrient signal to trigger autophagy and loss of both was sufficient to activate autophagy in the buffy mutant even in the presence of enforced phosphoinositide 3-kinase (PI3K signaling. Prior to starvation, the fed buffy mutant stored less lipid and glycogen, had high lactate levels and maintained a reduced pool of cellular ATP. These observations, together with the inability of buffy mutant larvae to adapt to nutrient restriction, indicate altered energy metabolism in the absence of buffy. Conclusions All animals in their natural habitats are faced with periods of reduced nutrient availability. This study demonstrates that buffy is required for adaptation to both starvation and nutrient restriction. Thus, Buffy is a Bcl-2 protein that plays an

  15. Maintaining workforce staffing and competence

    International Nuclear Information System (INIS)

    The French nuclear security system is a performance based system in which the nuclear operators have responsibility for the security of the nuclear material held in the facilities they operate. These operators have a choice of the means they use to fulfil their security obligations. Among the three main operators, two have decided to recruit and train their own staff, and the third has signed an agreement with the gendarmerie. Maintaining a high level of vigilance is an important and vital challenge, for which the management of the nuclear facilities is responsible and accountable. Flexibility, management support and commitment and repeated exercises are good means to reach this goal. However, no security system is appropriate unless the whole staff, those directly involved in security or otherwise, share a high degree of security culture. (author)

  16. Maintaining consistency in distributed systems

    Science.gov (United States)

    Birman, Kenneth P.

    1991-01-01

    In systems designed as assemblies of independently developed components, concurrent access to data or data structures normally arises within individual programs, and is controlled using mutual exclusion constructs, such as semaphores and monitors. Where data is persistent and/or sets of operation are related to one another, transactions or linearizability may be more appropriate. Systems that incorporate cooperative styles of distributed execution often replicate or distribute data within groups of components. In these cases, group oriented consistency properties must be maintained, and tools based on the virtual synchrony execution model greatly simplify the task confronting an application developer. All three styles of distributed computing are likely to be seen in future systems - often, within the same application. This leads us to propose an integrated approach that permits applications that use virtual synchrony with concurrent objects that respect a linearizability constraint, and vice versa. Transactional subsystems are treated as a special case of linearizability.

  17. Maintaining nuclear competence and expertise in Japan

    International Nuclear Information System (INIS)

    Full text: The fundamental law of atomic energy, which strictly restricts the application of atomic energy to the peaceful use, was established in 1955 in Japan. Since then, during the past five decades, great efforts were made to develop atomic energy. So far 52 units of light water reactors, 29 BWRs and 23 PWRs, have been built and in operation, 5 units are under construction and 6 units are planed to be built. Total capacity of presently operated NPPs amounts to 45.7 Gwe and the nuclear energy shares 30% of the total electricity generation in Japan. During the past 10 years, several accidents occur in the nuclear facilities of electric power companies, and JNC (previously PNC). In spite of these accidents, including the accident of Kansai Electric Power Co. this year, the important role of nuclear energy to sustain the lives of people in Japan is intact. In the nuclear energy projection, the construction of NPPs continues till 2010. Thereafter reconstructions of NPPs are foreseen in the decade 2030's for the replacement of present NPPs in operation after 60 years services. Attention has been directed to the technology preservation: how competence and expertise of nuclear engineering can be maintained till the next period of replacement construction, in particular, the period between years 2010 and 2030. The present paper reviews the status of nuclear engineering programs in universities in Japan. The nuclear education programs started in graduate schools in 1957 and expanded to undergraduate schools of major national universities. Presently nine universities are providing systematic nuclear education programs in their graduate schools, although the corresponding department have been changed their names from 'nuclear' to more broaden terms of 'quantum', 'energy' and 'system' in several universities. Under the conditions of shrinking nuclear industries, how to maintain the present education system is seriously concerned matter in the universities. The present

  18. Maintaining nuclear competence and expertise in Japan

    International Nuclear Information System (INIS)

    The fundamental law of atomic energy, which strictly restricts the application of atomic energy to the peaceful use, was established in 1955 in Japan. Since then, during the past five decades, great efforts were made to develop atomic energy. So far 52 units of light water reactors, 29 BWRs and 23 PWRs, have been built and in operation, 5 units are under construction and 6 units are planed to be built. Total capacity of presently operated NPPs amounts to 45.7 Gwe and the nuclear energy shares 30 % of the total electricity generation in Japan. During the past 10 years, several accidents occur in the nuclear facilities of electric power companies, and JNC ( previously PNC ). In spite of these accidents, including the accident of Kansai Electric Power Co. this year, the important role of nuclear energy to sustain the lives of people in Japan is intact. In the nuclear energy projection, the construction of NPPs continues till 2010. Thereafter reconstructions of NPPs are foreseen in the decade 2030's for the replacement of present NPPs in operation after 60 years services. Attention has been directed to the technology preservation: how competence and expertise of nuclear engineering can be maintained till the next period of replacement construction, in particular, the period between years 2010 and 2030. The present paper reviews the status of nuclear engineering programs in universities in Japan. The nuclear education programs started in graduate schools in 1957 and expanded to undergraduate schools of major national universities. Presently nine universities are providing systematic nuclear education programs in their graduate schools, although the corresponding department have been changed their names from 'nuclear' to more broaden terms of 'quantum', 'energy' and 'system' in several universities. Under the conditions of shrinking nuclear industries, how to maintain the present education system is seriously concerned matter in the universities. The present paper

  19. Software Code Maintainability : A Literature Review

    Directory of Open Access Journals (Sweden)

    Berna Seref

    2016-05-01

    Full Text Available Software Maintainability is one of the most important quality attributes. To increase quality of a software, to manage software more efficient and to decrease cost of the software, maintainability, maintainability estimation and maintainability evaluation models have been proposed. However, the practical use of these models in software engineering tools and practice remained little due to their limitations or threats to validity. In this paper, results of our Literature Review about maintainability models, maintainability metrics and maintainability estimation are presented. Aim of this paper is providing a baseline for further searches and serving the needs of developers and customers.

  20. Intellectualization of Design Technique for Product Maintainability

    Institute of Scientific and Technical Information of China (English)

    SHI Quan; SONG Yi-gang; CHENG Zhong-hua

    2004-01-01

    The basis of the two guideline lectures for maintainability design,namely "maintainability design criterions" and "cases compilation of maintainability design technique",an intellectualized architecture for combining rule-based reasoning(RBR)and case-based reasoning(CBR),is presented in this paper by analyzing from maintainability design procedure to the thought of our solving the maintainability design problem.Furthermore,the domain model and reasoning process is introduced and a representation of maintainability domain knowledge is given.Finally,the computer-aided engineering system for maintainability design(MCAES)which is based on intellectualized architecture is reported;its function and implementation is described.

  1. Maintaining quality in blood banking.

    Science.gov (United States)

    Harvey, E; Hewison, C; Nevalainen, D E; Lloyd, H L

    1995-03-01

    component will warrant redress. The degree of fault attributed to the producer will in part depend on whether they have met the best available standards at all stages in the preparation of the product. If a Transfusion Service can show that it's operation has external accreditation, particularly to an internationally recognised standard such as ISO 9000 and they can show that staff have been properly trained, that equipment is properly supplied and maintained and that the facility is appropriate to the work being carried out, then the liability that exists when something goes wrong will be reduced.(ABSTRACT TRUNCATED AT 400 WORDS) PMID:7795421

  2. Building and maintaining media relations

    International Nuclear Information System (INIS)

    Full text: In my opinion good media relations are among the most valuable investments regarding the communications and Public Relations operations within an Organisation. This means, that all the work you put up in building and maintaining media relations, is worth all the efforts. It can mean the difference between success or failure. Although a reporter never would admit that he or she is easily influenced, the fact is that you would get better press in an emergency case if you have a positive personal relation to the reporter. So, in my opinion there is nothing more important, in building and maintaining media relations, than the face-to-face-contact. My experience of good personal relations to reporters is also that you're not only getting better press in emergency cases. You are more successful in getting published when you have something positive to say, too. Honesty and openness are two key-words in this context. I have never tried to manipulate and delude a reporter, since that definitely would ruin the relationship. I always try to be as straight forward as possible and underline what I can say and what I can't. That instead of presenting some forced lies. For me, it is also very important to create some kind of mid-field ground, where the reporter and I can meet unprejudiced. Sense of humour and distance, both to yourself and your organisation, are two main characteristics that are invaluable in order to create a good personal relationship with a reporter. But, I'm very accurate in emphasizing when I enter my role as a company representative. All in order to be regarded as correct, yet obliging. To be quick when it comes to returning calls is another vital component that gives the reporter a feeling that he or she is important enough to be contacted as soon as possible. This service-minded attitude is of course good for the relationship. Besides the more personal relation it's important to have a business-like relation, where you show a great deal of

  3. 42 CFR 431.230 - Maintaining services.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Maintaining services. 431.230 Section 431.230 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Applicants and Recipients Procedures § 431.230 Maintaining services. (a) If the agency mails the 10-day or...

  4. Older Runners Can Maintain Their 'Fuel Efficiency'

    Science.gov (United States)

    ... 159291.html Older Runners Can Maintain Their 'Fuel Efficiency' Rate of oxygen consumption differs little between active ... body is like a car with a fuel efficiency level," Ortega said in a Humboldt State news ...

  5. Coastal Maintained Channels in US waters

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This layer shows coastal channels and waterways that are maintained and surveyed by the U.S. Army Corps of Engineers (USACE). These channels are necessary...

  6. Maintaining Intergenerational Solidarity in Mexican Transnational Families

    OpenAIRE

    Catherine A. Solheim; Jaime Ballard; Patricia D. Olson

    2016-01-01

    This study explored how Mexican transnational families maintain intergenerational relationships, using five of the dimensions of the intergenerational solidarity framework. Interview data from 13 adult migrant children who lived in the U.S. and their parents who lived in Mexico were analyzed. Structural solidarity was challenged by great distance between families. Families maintained associational solidarity by making contact frequently, though visiting was often restricted by lack of documen...

  7. Patients’ lived experiences regarding maintaining dignity

    OpenAIRE

    Cheraghi, Mohammad Ali; Manookian, Arpi; Nikbakht Nasrabadi, Alireza

    2015-01-01

    Preservation of dignity is frequently emphasized as a basic patient’s right in national and international nursing codes of ethics and is indeed the essence and core of nursing care. It is therefore essential to explore the concept based on patients’ lived experiences in order to maintain and respect their dignity and consequently improve the quality of health services and patient satisfaction. The present study aimed to discover the lived experiences of Iranian patients regarding maintaining ...

  8. Incrementally Maintaining Classification using an RDBMS

    OpenAIRE

    Koc, Mehmet Levent; Ré, Christopher

    2011-01-01

    The proliferation of imprecise data has motivated both researchers and the database industry to push statistical techniques into relational database management systems (RDBMSs). We study algorithms to maintain model-based views for a popular statistical technique, classification, inside an RDBMS in the presence of updates to the training examples. We make three technical contributions: (1) An algorithm that incrementally maintains classification inside an RDBMS. (2) An analysis of the above a...

  9. Maintaining Arc Consistency with Multiple Residues

    OpenAIRE

    Lecoutre, Christophe; Likitvivatanavong, Chavalit; Shannon, Scott; Yap, Roland; Zhang, Yuanlin

    2008-01-01

    International audience Exploiting residual supports (or residues) has proved to be one of the most cost-effective approaches for Maintaining Arc Consistency during search (MAC). While MAC based on optimal AC algorithm may have better theoretical time complexity in some cases, in practice the overhead for maintaining required data structure during search outweighs the benefit, not to mention themore complicated implementation. Implementing MAC with residues, on the other hand, is trivial. I...

  10. Maintainability program requirements for space systems

    Science.gov (United States)

    1987-01-01

    This document is established to provide common general requirements for all NASA programs to: design maintainability into all systems where maintenance is a factor in system operation and mission success; and ensure that maintainability characteristics are developed through the systems engineering process. These requirements are not new. Design for ease of maintenance and minimization of repair time have always been fundamental requirements of the systems engineering process. However, new or reusable orbital manned and in-flight maintainable unmanned space systems demand special emphasis on maintainability, and this document has been prepared to meet that need. Maintainability requirements on many NASA programs differ in phasing and task emphasis from requirements promulgated by other Government agencies. This difference is due to the research and development nature of NASA programs where quantities produced are generally small; therefore, the depth of logistics support typical of many programs is generally not warranted. The cost of excessive maintenance is very high due to the logistics problems associated with the space environment. The ability to provide timely maintenance often involves safety considerations for manned space flight applications. This document represents a basic set of requirements that will achieve a design for maintenance. These requirements are directed primarily at manned and unmanned orbital space systems. To be effective, maintainability requirements should be tailored to meet specific NASA program and project needs and constraints. NASA activities shall invoke the requirements of this document consistent with program planning in procurements or on inhouse development efforts.

  11. Energy.

    Science.gov (United States)

    Chambers, David W

    2012-01-01

    Energy is the capacity to do the things we are capable of and desire to accomplish. Most often this is thought of in terms of PEP--personal energy potential--a reservoir of individual vivacity and zest for work. Like a battery, energy can be conceived of as a resource that is alternatively used and replenished. Transitions between activities, variety of tasks, and choices of what to spend energy on are part of energy management. Energy capacity can be thought of at four levels: (a) so little that harm is caused and extraordinary steps are needed for recovery, (b) a deficit that slightly impairs performance but will recover naturally, (c) the typical range of functioning, and (d) a surplus that may or may not be useful and requires continual investment to maintain. "Flow" is the experience of optimal energy use when challenges balance capacity as a result of imposing order on our environment. There are other energy resources in addition to personal vim. Effective work design reduces demands on energy. Money, office design, and knowledge are excellent substitutes for personal energy. PMID:22856055

  12. Impact of Design Patterns on Software Maintainability

    Directory of Open Access Journals (Sweden)

    Fatimah Mohammed Alghamdi

    2014-09-01

    Full Text Available This paper mainly studies the effect of design patterns on the Software maintainability. Design patterns describe solutions for common design problems and they were introduced to improve software quality and accelerate software development. However, there are some difficulties to choose an optimal pattern adapted to a certain application and problem. So until now the results on the effect of design patterns on software quality are controversial. In this context, we propose a tool for design pattern guided that retrieves the appropriate pattern with respect to software maintainability from a repository of patterns. It measures the maintainability of design pattern by some metrics and candidate the more maintainable pattern to the designer or developer. It provides a support for decision making during system design and refactoring. As the results, the decision of applying a certain design pattern is usually a trade-off since the effect of design pattern on software maintainability is influenced by some factors such as the pattern size and the prior expertise of the developer.

  13. Maintaining Contour Trees of Dynamic Terrains

    DEFF Research Database (Denmark)

    Agarwal, Pankaj K.; Arge, Lars; Mølhave, Thomas; Revsbæk, Morten; Yang, Jungwoo

    We consider maintaining the contour tree T of a piecewise-linear triangulation M that is the graph of a time varying height function h:R2→R. We carefully describe the combinatorial change in T that happen as h varies over time and how these changes relate to topological changes in M. We present a...

  14. Competence in radiation protection - acquisition, maintaining, extending

    International Nuclear Information System (INIS)

    A survey is given on current initiatives, supranational in the EU and national in Germany and Switzerland, for education and training in radiation protection with the aim of maintaining and enlarging professional competence. Successively, individual studying possibilities and courses as well as some experiences with guidelines for professional knowledge in Germany are described. (orig.)

  15. How Do Positive Views Maintain Life Satisfaction?

    Science.gov (United States)

    Wu, Chia-Huei; Tsai, Ying-Mei; Chen, Lung Hung

    2009-01-01

    This study proposes three mediation pathways to explain how the positive views (perceived control, optimism and self-enhancement) proposed by Cummins and Nistico (Journal of Happiness Studies 3:37-69 2002) maintain life satisfaction. The three pathways were enhancing self-esteem, reducing have-want discrepancy and changing importance perceptions.…

  16. Requirements for Automated Assessment of Spreadsheet Maintainability

    CERN Document Server

    Correia, José Pedro

    2011-01-01

    The use of spreadsheets is widespread. Be it in business, finance, engineering or other areas, spreadsheets are created for their flexibility and ease to quickly model a problem. Very often they evolve from simple prototypes to implementations of crucial business logic. Spreadsheets that play a crucial role in an organization will naturally have a long lifespan and will be maintained and evolved by several people. Therefore, it is important not only to look at their reliability, i.e., how well is the intended functionality implemented, but also at their maintainability, i.e., how easy it is to diagnose a spreadsheet for deficiencies and modify it without degrading its quality. In this position paper we argue for the need to create a model to estimate the maintainability of a spreadsheet based on (automated) measurement. We propose to do so by applying a structured methodology that has already shown its value in the estimation of maintainability of software products. We also argue for the creation of a curated...

  17. Maintaining ideal body weight counseling sessions

    Energy Technology Data Exchange (ETDEWEB)

    Brammer, S.H.

    1980-10-09

    The purpose of this program is to provide employees with the motivation, knowledge and skills necessary to maintain ideal body weight throughout life. The target audience for this program, which is conducted in an industrial setting, is the employee 40 years of age or younger who is at or near his/her ideal body weight.

  18. The randomized complexity of maintaining the minimum

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Chaudhuri, Shiva; Radhakrishnan, Jaikumar

    1996-01-01

    The complexity of maintaining a set under the operations Insert, Delete and FindMin is considered. In the comparison model it is shown that any randomized algorithm with expected amortized cost t comparisons per Insert and Delete has expected cost at least n/(e22t)-1 comparisons for FindMin. If F......The complexity of maintaining a set under the operations Insert, Delete and FindMin is considered. In the comparison model it is shown that any randomized algorithm with expected amortized cost t comparisons per Insert and Delete has expected cost at least n/(e22t)-1 comparisons for Find......Min. If FindMin is replaced by a weaker operation. FindAny, then it is shown that a randomized algorithm with constant expected cost per operation exists; in contrast, it is shown that no deterministic algorithm can have constant cost per operation. Finally, a deterministic algorithm with constant amortized...

  19. Experimental control for initiating and maintaining rotation of parametric pendulum

    Science.gov (United States)

    Vaziri, V.; Najdecka, A.; Wiercigroch, M.

    2014-04-01

    In this paper, the authors have studied experimentally the control methods of a parametric pendulum excited harmonically to initiate and maintain a period one rotation - the most superior response for energy harvesting. For initiating the period one rotation inherent in the system, first the bang-bang method is applied. Then a new method where velocity is monitored is proposed and applied and finally the time-delayed feedback method with multi-switching is considered. Ultimately the problem of maintaining the rotation of the pendulum is addressed. For first time, robustness and sensitivity of the latter method to change of frequency and amplitude of excitation and added noise are studied. Finally, it has been demonstrated how the delayed feedback method can be applied in a system of two pendula to ensure synchronized rotation.

  20. The importance of university research in maintaining the nuclear option

    International Nuclear Information System (INIS)

    The role of the university in maintaining and revitalizing the nuclear option should have four goals. First, it must attract highly skilled students who have an interest in math and science and help foster their interest in nuclear science and engineering. Next, it must present a state-of-the-art educational program that contains meaningful research to maintain these students. The third goal of nuclear engineering departments is to provide the nontechnical student a fair assessment of benefits and risks associated with commercial nuclear power relative to other sources of electricity. Lastly, it must effectively communicate to all students a compelling vision of nuclear power as a vital energy resource that will grow. The most difficult role for the university is to successfully convey a future for those in the nuclear science and engineering program

  1. Methods for Maintaining Insect Cell Cultures

    OpenAIRE

    Dwight E. Lynn

    2002-01-01

    Insect cell cultures are now commonly used in insect physiology, developmental biology, pathology, and molecular biology. As the field has advanced from methods development to a standard procedure, so has the diversity of scientists using the technique. This paper describes methods that are effective for maintaining various insect cell lines. The procedures are differentiated between loosely or non-attached cell strains, attached cell strains, and strongly adherent cell strains.

  2. Management Indicators: Assessing Product Reliability and Maintainability

    OpenAIRE

    Rosson, Constance V.

    1988-01-01

    This report discusses the role of Management Indicators in validating the predictive capability of the bottom-up evaluation process, which is defined by the Procedural Approach to the Evaluation of Software Development Methodologies. The bottom-up evaluation process provides a framework for determining the extent to which software engineering objectives, e.g., reliability and maintainability, are present in a software product from a design perspective of the code and supporting documentation....

  3. Impact of Design Patterns on Software Maintainability

    OpenAIRE

    Fatimah Mohammed Alghamdi; M. Rizwan Jameel Qureshi

    2014-01-01

    This paper mainly studies the effect of design patterns on the Software maintainability. Design patterns describe solutions for common design problems and they were introduced to improve software quality and accelerate software development. However, there are some difficulties to choose an optimal pattern adapted to a certain application and problem. So until now the results on the effect of design patterns on software quality are controversial. In this context, we propose a tool for design ...

  4. Importance of heterotrophic adaptations of corals to maintain energy reserves

    OpenAIRE

    Seemann, Janina; Carballo-Bolanos, R.; Berry, K. L.; González, C. T.; Richter, Claudio; Leinfelder, R. R.

    2012-01-01

    We examined the ability of the two hard coral species Agaricia tenuifolia and Porites furcata to store lipids under natural conditions, under experimental starvation (weekly vs. daily feeding) and under heat stress. P. furcata fed more and accumulated greater lipid quantities than A. tenuifolia. Overall, lipid levels in situ showed an inverse relationship to turbidity and eutrophication with highest values at the least anthropogenically impacted site. Although zooxanthellae, chlorophyll a con...

  5. Identifying crucial parameter correlations maintaining bursting activity.

    Directory of Open Access Journals (Sweden)

    Anca Doloc-Mihu

    2014-06-01

    Full Text Available Recent experimental and computational studies suggest that linearly correlated sets of parameters (intrinsic and synaptic properties of neurons allow central pattern-generating networks to produce and maintain their rhythmic activity regardless of changing internal and external conditions. To determine the role of correlated conductances in the robust maintenance of functional bursting activity, we used our existing database of half-center oscillator (HCO model instances of the leech heartbeat CPG. From the database, we identified functional activity groups of burster (isolated neuron and half-center oscillator model instances and realistic subgroups of each that showed burst characteristics (principally period and spike frequency similar to the animal. To find linear correlations among the conductance parameters maintaining functional leech bursting activity, we applied Principal Component Analysis (PCA to each of these four groups. PCA identified a set of three maximal conductances (leak current, [Formula: see text]Leak; a persistent K current, [Formula: see text]K2; and of a persistent Na+ current, [Formula: see text]P that correlate linearly for the two groups of burster instances but not for the HCO groups. Visualizations of HCO instances in a reduced space suggested that there might be non-linear relationships between these parameters for these instances. Experimental studies have shown that period is a key attribute influenced by modulatory inputs and temperature variations in heart interneurons. Thus, we explored the sensitivity of period to changes in maximal conductances of [Formula: see text]Leak, [Formula: see text]K2, and [Formula: see text]P, and we found that for our realistic bursters the effect of these parameters on period could not be assessed because when varied individually bursting activity was not maintained.

  6. Laboratory services: regaining and maintaining control.

    Science.gov (United States)

    Lee, Graham R; Fitzgibbon, Maria C; O'Shea, Paula

    2016-06-13

    Purpose - After implementing an internal quality control (IQC) programme, the purpose of this paper is to maintain the requisite analytical performance for clinical laboratory staff, thereby safeguarding patient test results for their intended medical purpose. Design/methodology/approach - The authors address how quality can be maintained and if lost, how it can be regained. The methodology is based on the experience working in clinical laboratory diagnostics and is in accord with both international accreditation requirements and laboratory best practice guidelines. Findings - Monitoring test performance usually involves both prospective and retrospective IQC data analysis. The authors present a number of different approaches together with software tools currently available and emerging, that permit performance monitoring at the level of the individual analyser, across analysers and laboratories (networks). The authors make recommendations on the appropriate response to IQC rule warnings, failures and metrics that indicate analytical control loss, that either precludes further analysis, or signifies deteriorating performance and eventual unsuitability. The authors provide guidance on systematic troubleshooting, to identify undesirable performance and consider risk assessment preventive measures and continuous quality improvement initiatives; e.g., material acceptance procedures, as tools to help regain and maintain analytical control and minimise potential for patient harm. Practical implications - The authors provide a template for use by laboratory scientific personnel that ensures the optimal monitoring of analytical test performance and response when it changes undesirably. Originality/value - The proposed template has been designed to meet the International Organisation for Standardisation for medical laboratories ISO15189:2012 requirements and therefore includes the use of External Quality Assessment and patient results data, as an adjunct to IQC data. PMID

  7. Take Control of Maintaining Your Mac

    CERN Document Server

    Kissell, Joe

    2009-01-01

    Keep your Mac running smoothly with our easy maintenance program! Regular maintenance is necessary to avoid problems and to ensure your Mac runs at peak performance, but it's hard to know what to do and when to do it. Best-selling author Joe Kissell has now applied his commonsense approach to the task of maintaining your Mac, whether you use Tiger or Leopard! Learn how to start on the right foot; what you should do daily, weekly, monthly, and yearly; and how to prepare for Mac OS X updates. Joe even explains how to monitor your Mac's health and debunks common panaceas. Read this book to lea

  8. Maintaining Intergenerational Solidarity in Mexican Transnational Families

    Directory of Open Access Journals (Sweden)

    Catherine A. Solheim

    2016-02-01

    Full Text Available This study explored how Mexican transnational families maintain intergenerational relationships, using five of the dimensions of the intergenerational solidarity framework. Interview data from 13 adult migrant children who lived in the U.S. and their parents who lived in Mexico were analyzed. Structural solidarity was challenged by great distance between families. Families maintained associational solidarity by making contact frequently, though visiting was often restricted by lack of documentation. Functional solidarity was expressed through financial support to parents. This involved remittances sent to parents. However, it should be noted that it was often migrants’ siblings in Mexico who managed these remittances. Affectual solidarity was expressed through statements of love and concern for one another. Normative solidarity and consensual solidarity reflected the value of familismo through financial support and the desire to live together. Several dimensions of intergenerational solidarity are interconnected. This study provides evidence for the relevance of the intergenerational solidarity framework in transnational families and suggests that geographic context is relevant when studying intergenerational relationships.

  9. Maintaining extensivity in evolutionary multiplex networks

    CERN Document Server

    Antonopoulos, Chris G

    2015-01-01

    In this Letter, we explore the role of network topology on its extensive character. We study analytically and numerically how the topology contributes to maintaining extensivity of entropy in multiplex networks, i.e. networks of subnetworks, by means of the sum of the positive Lyapunov exponents, $H_{KS}$, a quantity related to entropy. We show that extensivity relies not only on the interplay between the coupling strengths of the dynamics associated to the intra (short-range) and inter (long-range) interactions, but also on the sum of the intra-degrees of the nodes of the subnetworks. For the analytically treated networks of size $N$, if the sum of the intra-degrees (and the sum of inter-degrees) scales as $N^{\\theta+1}$, extensivity can be maintained if the intra-coupling (and the inter-coupling) strength scales as $N^{-\\theta}$, when evolution is driven by the maximization of $H_{KS}$. We then verify our analytical result by doing numerical simulations in multiplex networks formed by electrically and chemi...

  10. To Grow, Nurture, and Maintain: Soil

    Science.gov (United States)

    Joshi, I.; Lam, K.; Hennelly, L. O.; Archie, J. P.

    2012-12-01

    The importance and difficulties encountered in a sustainable urban farm can be witnessed at the Stanford Earth Systems Educational Garden, in the growth, maintenance, and nurturing of the soil. Techniques and chemicals developed in the mid to late 1900's have infiltrated the traditional farming techniques that allowed humans to continuously farm for hundreds of years. The sudden spur of interest in sustainability has lead many, including Stanford Earth Systems, to reincorporate traditional methods in conjunction with modern technology. To override the damage made by chemicals and industrial farming, we had to recognize that healthy crops originated from healthy soil; thus we began investigating how to nourish soil. We began to research the ideal composition and structure of soil and methods to create and maintain fertile soil. Secondly, we prioritized the importance of nurturing plants and fed the plants with a plethora of natural fertilizers. We also created a compost pile so that the soil could rehabilitate and refill with nutrients with help provided by bacteria. Lastly, we had to maintain the soil to keep the soil viable for future crops. To do this, we had to acknowledge the chemical composition of the soil and plant cover crops to ensure that the nutrients are replenished. Our experiences enabled us to understand the time and effort required to manage suitable crops, animals, and structures for an urban farm.

  11. Online maintaining appearance model using particle filter

    Science.gov (United States)

    Chen, Siying; Lan, Tian; Wang, Jianyu; Ni, Guoqiang

    2008-03-01

    Tracking by foreground matching heavily depends on the appearance model to establish object correspondences among frames and essentially, the appearance model should encode both the difference part between the object and background to guarantee the robustness and the stable part to ensure tracking consistency. This paper provides a solution for online maintaining appearance models by adjusting features in the model. Object appearance is co-modeled by a subset of Haar features selected from the over-complete feature dictionary which encodes the discriminative part of object appearance and the color histogram which describes the stable appearance. During the particle filtering process, feature values both from background patches and object observations are sampled efficiently by the aid of "foreground" and "background" particles respectively. Based on these sampled values, top-ranked discriminative features are added and invalid features are removed out to ensure the object being distinguishable from current background according to the evolving appearance model. The tracker based on this online appearance model maintaining technique has been tested on people and car tracking tasks and promising experimental results are obtained.

  12. Maintaining human productivity during Mars transit

    Science.gov (United States)

    Statler, Irving C.; Billings, Charles E.

    1989-01-01

    This paper addresses the special nature of the human-machine relationship during a trip to Mars. In particular, the potential for monotony and boredom during a long-duration space voyage and the effect on motivation and productivity can be important considerations to the health and welfare of the crew. For the voyage to Mars, a design may be considered that will purposefully maintain some level of workload for the crew as a preventive measure for the deterioration of productivity that comes with boredom. This paper speculates on these considerations, on the appropriate level of workload for maximum productivity, and on what might be done during the mission to alleviate the problems caused by monotony and boredom.

  13. Maintaining and improving accredited training programs

    International Nuclear Information System (INIS)

    The US nuclear industry's mission has been to upgrade its training efforts. The industry chose the Institute of Nuclear Power Operations accreditation program as the vehicle to help it accomplish this goal. The result is that operational training programs are now in use at all the operating plants for ten key plant positions. This is just the beginning of the industry's quest for training excellence. The ultimate objective to be achieved is to maintain high quality training and the professionalism of the personnel who operate the nuclear power plants. These training programs must now be implemented with qualified instructors. The training materials and equipment, such as the simulator, must be kept current. The feedback on the effectiveness of training must be obtained

  14. Maintaining the Telescope Bibliography at Gemini Observatory

    Science.gov (United States)

    Zhang, X.

    2010-10-01

    The library profession benefits tremendously from ever-changing web technologies. In maintaining a telescope bibliography, web-publishing revolutionized the way librarians track relevant publications. Thanks to the search abilities provided by the NASA Astrophysics Data System, arXiv, publishers, as well as Google Scholar, and other such resources, online searching for Gemini-based publications has replaced the tedious perusing of print journals. However, we should keep in mind that online searching is neither flawless nor simple — different content providers require different search strategies. Sometimes the retrievals are not as complete as one expects. Information providers should be constantly improving their searching abilities in order to make the task of electronic publication tracking more reliable and efficient.

  15. Maintaining and troubleshooting your 3D printer

    CERN Document Server

    Bell, Charles

    2014-01-01

    Maintaining and Troubleshooting Your 3D Printer by Charles Bell is your guide to keeping your 3D printer running through preventive maintenance, repair, and diagnosing and solving problems in 3D printing. If you've bought or built a 3D printer such as a MakerBot only to be confounded by jagged edges, corner lift, top layers that aren't solid, or any of a myriad of other problems that plague 3D printer enthusiasts, then here is the book to help you get past all that and recapture the joy of creative fabrication. The book also includes valuable tips for builders and those who want to modify the

  16. Maintaining Quality in a Decommissioning Environment

    International Nuclear Information System (INIS)

    The decommissioning of AECL's Whiteshell Laboratories is Canada's largest nuclear decommissioning project to date. This research laboratory has operated for forty years since it was set up in 1963 in eastern Manitoba as the Whiteshell Nuclear Research Establishment, complete with 60 MW(Th) test reactor, hot cells, particle accelerators, and multiple large-scale research programs. Returning the site to almost complete green state will require several decades of steady work in combination with periods of storage-with-surveillance. In this paper our approach to maintaining quality during the long decommissioning period is explained. In this context, 'quality' includes both regulatory aspects (compliance with required standards) and business aspects (meeting the customers' needs and exceeding their expectations). Both aspects are discussed, including examples and lessons learned. The five years of development and implementation of a quality assurance program for decommissioning the WL site have led to a number of lessons learned. Many of these are also relevant to other decommissioning projects, in Canada and elsewhere: - Early discussions with the regulator can save time and effort later in the process; - An iterative process in developing documentation allows for steady improvements and input throughout the process; - Consistent 2-way communication with staff regarding the benefits of a quality program assists greatly in adoption of the philosophy and procedures; - Top-level management must lead in promoting quality; - Field trials of procedures ('beta testing') ensures they are easy to use as well as useful. Success in decommissioning the Whiteshell Laboratories depends on the successful implementation of a rigorous quality program. This will help to ensure both safety and efficiency of all activities on site, from planning through execution and reporting. The many aspects of maintaining this program will continue to occupy quality practitioners in AECL, reaping

  17. Communicating contentious geoscience issues and maintaining impartiality

    Science.gov (United States)

    Nice, S. E.; Mitchell, C.

    2013-12-01

    Shale Gas exploration in the UK has been major and often controversial news in the British media over the last 2 years. The British Geological Survey (BGS) has been an integral part of this story as the UK Governments independent and impartial advisor on geosciences. BGS has been involved in writing policy on fracking and induced earthquakes as well as researching potential quantities of shale gas in the UK and also researching natural methane levels in groundwater before large scale fracking activities begin. Shale Gas in the UK, as in the US and Europe has caused much controversy and as a result has many pro and anti fracking campaigns. The challenge for BGS has been to deliver front line science, whilst maintaining complete impartiality on the subject. The BGS communications team developed a strategy over this period to ensure that our message was clear and strong. This involved working closely with the scientists involved to formulate key messages that could delivered through controlled statements on the BGS webpages, press releases, at press conferences as well as on broadcast and print media. Our scientists were media trained during this time to ensure that they stayed en message and wouldn't be caught by the press or opponents of fracking into making statements that could have been used to either scare up the position or give the antagonist room to cast doubt on our impartiality. This strategy proved highly successful and BGS managed to communicate the facts, remain impartial whilst avoiding attempts to undermine the potential for Shale gas exploitation in the UK. The success of this communication strategy was due to the cooperation of the scientists, a clear strategy from the communications team and the unequivocal support of the senior executive at BGS. This abstract will conclude how the BGS has developed its communication strategy to be more streamlined and open. BGS must allow it's scientists to talk to the media about the science that they do. Much of

  18. Níveis de energia metabolizável para frangos de corte no período de 22 a 42 dias de idade mantidos em ambiente termoneutro Metabolizable energy level for broilers from 22 to 42 days of age maintained under thermoneutral environment

    Directory of Open Access Journals (Sweden)

    Adhemar Rodrigues de Oliveira Neto

    2000-08-01

    Full Text Available Este experimento foi realizado para avaliar os efeitos de níveis de energia metabolizável (EM da ração sobre desempenho, qualidade de carcaça e variáveis fisiológicas de frangos de corte dos 22 aos 42 dias de idade mantidos em ambiente de termoneutralidade (23,2+0,74ºC. Foram utilizados 240 frangos de corte machos Hubbard, com peso médio inicial de 753+3,03 g, em delineamento inteiramente casualizado com cinco tratamentos (3000, 3075, 3150, 3225 e 3300 kcal de energia metabolizável/kg de ração, seis repetições e oito aves por unidade experimental. As rações experimentais isoprotéicas foram fornecidas às aves de forma controlada, correspondente a 95% do consumo voluntário, para que o consumo de proteína fosse igual em todos os tratamentos. O ganho de peso, o consumo de EM, a conversão alimentar e as deposições de proteína e gordura na carcaça melhoraram linearmente com o aumento do nível de EM da ração, enquanto o rendimento de carcaça diminuiu de forma linear com o nível de EM. Não foi verificado efeito do nível de EM das rações sobre os pesos absoluto e relativo de coxas, sobrecoxas, pernas e peito com osso e sem osso, coração, fígado, moela proventrículo, pulmões, intestino, gordura abdominal e penas. Não se observou efeito do nível de EM da ração sobre a concentração sérica de triiodotironina livre. O nível de 3232 kcal de EM, correspondente à relação energia:proteína calculada de 16,49, proporcionou os melhores resultados de desempenho e deposição de proteína na carcaça dos frangos de corte mantidos em ambiente termoneutro.This experiment was conducted to evaluate the effects of metabolizable energy (ME levels on performance, carcass quality and physiological traits of broilers from 22 to 42 days of age maintained under thermoneutral environment (23.2±0.74ºC. Two hundred and forty Hubbard male broilers with average weight of 753±3.03 g were used in a completely randomized design with

  19. MAVS maintains mitochondrial homeostasis via autophagy.

    Science.gov (United States)

    Sun, Xiaofeng; Sun, Liwei; Zhao, Yuanyuan; Li, Ying; Lin, Wei; Chen, Dahua; Sun, Qinmiao

    2016-01-01

    Mitochondrial antiviral signalling protein (MAVS) acts as a critical adaptor protein to transduce antiviral signalling by physically interacting with activated RIG-I and MDA5 receptors. MAVS executes its functions at the outer membrane of mitochondria to regulate downstream antiviral signalling, indicating that the mitochondria provides a functional platform for innate antiviral signalling transduction. However, little is known about whether and how MAVS-mediated antiviral signalling contributes to mitochondrial homeostasis. Here we show that the activation of MAVS is sufficient to induce autophagic signalling, which may mediate the turnover of the damaged mitochondria. Importantly, we find MAVS directly interacts with LC3 through its LC3-binding motif 'YxxI', suggesting that MAVS might act as an autophagy receptor to mediate mitochondrial turnover upon excessive activation of RLR signalling. Furthermore, we provide evidence that both MAVS self-aggregation and its interaction with TRAF2/6 proteins are important for MAVS-mediated mitochondrial turnover. Collectively, our findings suggest that MAVS acts as a potential receptor for mitochondria-associated autophagic signalling to maintain mitochondrial homeostasis. PMID:27551434

  20. Virus Movement Maintains Local Virus Population Diversity

    Energy Technology Data Exchange (ETDEWEB)

    J. Snyder; B. Wiedenheft; M. Lavin; F. Roberto; J. Spuhler; A. Ortmann; T. Douglas; M. Young

    2007-11-01

    Viruses are the largest reservoir of genetic material on the planet, yet little is known about the population dynamics of any virus within its natural environment. Over a 2-year period, we monitored the diversity of two archaeal viruses found in hot springs within Yellowstone National Park (YNP). Both temporal phylogeny and neutral biodiversity models reveal that virus diversity in these local environments is not being maintained by mutation but rather by high rates of immigration from a globally distributed metacommunity. These results indicate that geographically isolated hot springs are readily able to exchange viruses. The importance of virus movement is supported by the detection of virus particles in air samples collected over YNP hot springs and by their detection in metacommunity sequencing projects conducted in the Sargasso Sea. Rapid rates of virus movement are not expected to be unique to these archaeal viruses but rather a common feature among virus metacommunities. The finding that virus immigration rather than mutation can dominate community structure has significant implications for understanding virus circulation and the role that viruses play in ecology and evolution by providing a reservoir of mobile genetic material.

  1. Exploring how nurse lecturers maintain clinical credibility.

    Science.gov (United States)

    Fisher, Melanie T

    2005-01-01

    The role of the nurse lecturer is changing. There is growing pressure from the government and professionals alike to recruit nurse teachers who posses both practical and recent experience of nursing [Department of Health, 1999. Making a Difference: Strengthening the Nursing, Midwifery and Health Visiting Contribution to Health and Health Care. DOH, London; UKCC, 2000. Standards for the Preparation of Teachers of Nursing, Midwifery and Health Visiting. UKCC, London]. Whilst much of the literature available suggests a growing concern amongst practitioners, students and nurse educationalists themselves about the importance of being ;clinically credible', what is not clear is how tangible it is to maintain currency and clinical credibility. In addition, the term ;clinical credibility' is in itself ill-defined. An exploratory study was undertaken within one higher education institution which sought to seek the views of nurse lecturers. The principles of ethnography were applied to this research. The sample included six of the most recently appointed nurse lecturers within one academic faculty who taught predominantly on pre-registration programmes. Data from individual and focus group interviews was analysed using a thematic content analysis approach. The findings are discussed which embrace the concepts of: working ;hands on' in the clinical area, clinical currency, transferability of skills, clinical visibility and role development. Recommendations for the development of professional practice are offered. PMID:19038175

  2. Achieving and maintaining cognitive vitality with aging.

    Science.gov (United States)

    Fillit, Howard M; Butler, Robert N; O'Connell, Alan W; Albert, Marilyn S; Birren, James E; Cotman, Carl W; Greenough, William T; Gold, Paul E; Kramer, Arthur F; Kuller, Lewis H; Perls, Thomas T; Sahagan, Barbara G; Tully, Tim

    2002-07-01

    Cognitive vitality is essential to quality of life and survival in old age. With normal aging, cognitive changes such as slowed speed of processing are common, but there is substantial interindividual variability, and cognitive decline is clearly not inevitable. In this review, we focus on recent research investigating the association of various lifestyle factors and medical comorbidities with cognitive aging. Most of these factors are potentially modifiable or manageable, and some are protective. For example, animal and human studies suggest that lifelong learning, mental and physical exercise, continuing social engagement, stress reduction, and proper nutrition may be important factors in promoting cognitive vitality in aging. Manageable medical comorbidities, such as diabetes, hypertension, and hyperlipidemia, also contribute to cognitive decline in older persons. Other comorbidities such as smoking and excess alcohol intake may contribute to cognitive decline, and avoiding these activities may promote cognitive vitality in aging. Various therapeutics, including cognitive enhancers and protective agents such as antioxidants and anti-inflammatories, may eventually prove useful as adjuncts for the prevention and treatment of cognitive decline with aging. The data presented in this review should interest physicians who provide preventive care management to middle-aged and older individuals who seek to maintain cognitive vitality with aging. PMID:12108606

  3. 34 CFR 668.163 - Maintaining and accounting for funds.

    Science.gov (United States)

    2010-07-01

    ...) Accounting and internal control systems and financial records. (1) An institution must maintain accounting... 34 Education 3 2010-07-01 2010-07-01 false Maintaining and accounting for funds. 668.163 Section... Maintaining and accounting for funds. (a)(1) Bank or investment account. An institution must maintain title...

  4. Andean flat subduction maintained by slab tunneling

    Science.gov (United States)

    Schepers, Gerben; van Hinsbergen, Douwe; Kosters, Martha; Boschman, Lydian; McQuarrie, Nadine; Spakman, Wim

    2016-04-01

    In two segments below the Andean mountain belt, the Nazca Plate is currently subducting sub-horizontally below South America over a distance of 200-300 km before the plate bends into the mantle. Such flat slab segments have pronounced effects on orogenesis and magmatism and are widely believed to be caused by the downgoing plate resisting subduction due to its local positive buoyancy. In contrast, here we show that flat slabs primarily result from a local resistance against rollback rather than against subduction. From a kinematic reconstruction of the Andean fold-thrust belt we determine up to ~390 km of shortening since ~50 Ma. During this time the South American Plate moved ~1400 km westward relative to the mantle, thus forcing ~1000 km of trench retreat. Importantly, since the 11-12 Ma onset of flat slab formation, ~1000 km of Nazca Plate subduction occurred, much more than the flat slab lengths, which leads to our main finding that the flat slabs, while being initiated by arrival of buoyant material at the trench, are primarily maintained by locally impeded rollback. We suggest that dynamic support of flat subduction comes from the formation of slab tunnels below segments with the most buoyant material. These tunnels trap mantle material until tearing of the tunnel wall provides an escape route. Fast subduction of this tear is followed by a continuous slab and the process can recur during ongoing rollback of the 7000 km wide Nazca slab at segments with the most buoyant subducting material, explaining the regional and transient character of flat slabs. Our study highlights the importance of studying subduction dynamics in absolute plate motion context.

  5. Position paper on maintaining nuclear competence

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-04-15

    The ENS Higher Scientific Council (HSC) is concerned about the current negative developments within some Member States of the EU and the consequential reduced perspectives in the field of nuclear energy technology, education, research and development. The HSC believes that the use of nuclear energy provides an essential contribution to the secure, clean and affordable energy supply for electricity generation, and that this will remain for at least the rest of this century. The HSC, therefore, strongly recommends that within the EU the resources that are allocated to nuclear education and training and to nuclear R and D reflects the increasing globalization of nuclear power and the needs of Member States that will have nuclear power or decommissioning programmes for decades to come. In addition, the HSC recommends that the nuclear industry should actively encourage the setting up of knowledge transfer mechanisms to ensure that the knowledge, know-how and experiences of the current generation of professionals within the industry is not lost to the young people entering nuclear careers. Mobility programmes to support and encourage young professionals to work across the EU to gain wider experience of nuclear power operations should be set up. These activities should help young professionals working in the nuclear technology field to expand long-life networks and business connections and thereby be better prepared for the challenges of the 21{sup st} century. (orig.)

  6. Position paper on maintaining nuclear competence

    International Nuclear Information System (INIS)

    The ENS Higher Scientific Council (HSC) is concerned about the current negative developments within some Member States of the EU and the consequential reduced perspectives in the field of nuclear energy technology, education, research and development. The HSC believes that the use of nuclear energy provides an essential contribution to the secure, clean and affordable energy supply for electricity generation, and that this will remain for at least the rest of this century. The HSC, therefore, strongly recommends that within the EU the resources that are allocated to nuclear education and training and to nuclear R and D reflects the increasing globalization of nuclear power and the needs of Member States that will have nuclear power or decommissioning programmes for decades to come. In addition, the HSC recommends that the nuclear industry should actively encourage the setting up of knowledge transfer mechanisms to ensure that the knowledge, know-how and experiences of the current generation of professionals within the industry is not lost to the young people entering nuclear careers. Mobility programmes to support and encourage young professionals to work across the EU to gain wider experience of nuclear power operations should be set up. These activities should help young professionals working in the nuclear technology field to expand long-life networks and business connections and thereby be better prepared for the challenges of the 21st century. (orig.)

  7. The critical power to maintain thermally stable molecular junctions

    Science.gov (United States)

    Wang, Yanlei; Xu, Zhiping

    2014-07-01

    With the rise of atomic-scale devices such as molecular electronics and scanning probe microscopies, energy transport processes through molecular junctions have attracted notable research interest recently. In this work, heat dissipation and transport across diamond/benzene/diamond molecular junctions are explored by performing atomistic simulations. We identify the critical power Pcr to maintain thermal stability of the junction through efficient dissipation of local heat. We also find that the molecule-probe contact features a power-dependent interfacial thermal resistance RK in the order of 109 kW-1. Moreover, both Pcr and RK display explicit dependence on atomic structures of the junction, force and temperature. For instance, Pcr can be elevated in multiple-molecule junctions, and streching the junction enhances RK by a factor of 2. The applications of these findings in molecular electronics and scanning probing measurements are discussed, providing practical guidelines in their rational design.

  8. A Maintainability Prediction Method Considering Environmental Impacts and Cost

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Maintainability prediction is one kind of primary maintainability action. Design deficiency would be found through predicting maintainability parameters under certain conditions. Now a maintainability prediction method that mainly considers maintenance time or maintenance man-hour is a kind of prediction method with a single index. With increasing product complexity and people's environmental consciousness, more attention is paid to environment impacts and maintenance cost or resource consumption in the maintenance process. It is necessary for a maintainability prediction method that can predict maintenance cost and maintenance environmental impacts. A new maintainability prediction method is presented in this paper based on analyzing existing maintainability prediction methods.The method is MABTCE (maintenance activity based timing/costing/environment impact assessment )and can predict maintenance time, maintenance costing and maintenance environmental impacts andthen improve maintainability design with prediction results.

  9. Fuzzy Maintainability Model for Object Oriented Software System

    Directory of Open Access Journals (Sweden)

    Soumi Ghosh

    2012-07-01

    Full Text Available In recent years for achieving considerable success in software system, maintainability plays a very crucial role and it is considered as an important quality characteristics. In this paper a maintainability model has been proposed to compare maintainability of object-oriented software system. Attempts have been made on software developed in different programming languages to make comparison of maintainability pattern using AHP and Fuzzy Index method.

  10. Fuzzy Maintainability Model for Object Oriented Software System

    OpenAIRE

    Soumi Ghosh; Sanjay Kumar Dubey; Ajay Rana

    2012-01-01

    In recent years for achieving considerable success in software system, maintainability plays a very crucial role and it is considered as an important quality characteristics. In this paper a maintainability model has been proposed to compare maintainability of object-oriented software system. Attempts have been made on software developed in different programming languages to make comparison of maintainability pattern using AHP and Fuzzy Index method.

  11. China Maintains World No.1in Terms of Auto Production and Sales in2010%China Maintains World No.1in Terms of Auto Production and Sales in 2010

    Institute of Scientific and Technical Information of China (English)

    Li Zao

    2011-01-01

    @@ Figures from the China Association of Automobile Manufacturers show that the auto industry of China maintained the development tendency of the last year in2010 under the accumulation effect of many consumption encouraging policies such as purchase tax concession,old for new service,car subsidy program for rural areas,energy-saving products discount,both the auto production and the sales exceeding 18 million units,maintaining its position as the world No.1,achieving 18.2647 million units and 18.0619 million units respectively,with an increase of 32.44% and 32.37% on a year-on-year basis.

  12. Research on Maintainability Evaluation Model Based on Fuzzy Theory

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Maintainability influencing attributes are analyzed, their weight and value calculating methods are given, and the maintainability fuzzy evaluation method is proposed based on the relative closeness. According to the maintenance task simulation operated in virtual environment, the maintainability virtual evaluation model is built by analyzing the maintenance task for each replaceable unit of product.At last, a case study is given based upon the main landing gear system of a certain type civil aircraft, and the result indicates that the model is suitable for maintainability qualitative evaluation and can support maintainability concurrent design.

  13. Maintainability - a means to improve the maintenance and availability performance of nuclear power plants

    International Nuclear Information System (INIS)

    The main purpose in this paper is to attract attention of nuclear power plant owners and their suppliers to the subjects of plant maintenance and maintainability. It is firmly believed by the authors that these characteristics must be considered on equal footing with safety, performance, quality, reliability, and costs during the plant design phase. Operating experience trends from a number of existing plants, as they grew older, indicates that plant availability is decreasing and the maintenance costs are increasing, significantly because the plant maintainability was inadequately considered during their design. Also, very little, if any, consideration was given to facilitate work relating to plant refurbishment / life extension thus causing longer refurbishment outages with higher attendant costs. Further, the energy generated from nuclear generation, when not available, is generally replaced by the energy from the fossil plants with high fuelling costs and adverse environmental effects. Also, to maintain electrical power system reliability, additional generation reserves must be provided which further add to the costs. This paper identifies incentives for improved plant maintainability in terms of higher plant availability, lower life cycle costs, improved safety and radiation dose expenditure. It identifies fundamental principles such as design simplicity, use of standard and / or modular designs, better plant lay-out and access to equipment, trained / qualified staff, etc. for incorporating maintainability in design. In order to optimize maintenance effort, control maintenance costs, the paper espouses maintainability as a key parameter of design and proposes a system's approach to design integrating maintainability and maintenance support planning tasks with design activities. These tasks involve: Performing appropriate maintainability engineering tasks in design. This for example will include: review of past experience, definition of plant and equipment

  14. 78 FR 144 - Application for a Presidential Permit To Operate and Maintain Pipeline Facilities on the Border...

    Science.gov (United States)

    2013-01-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Application for a Presidential Permit To Operate and Maintain Pipeline Facilities on the Border of the United... Energy, Limited Partnership Application for a Presidential Permit to Operate and Maintain...

  15. 4 CFR 200.14 - Responsibility for maintaining adequate safeguards.

    Science.gov (United States)

    2010-01-01

    ... maintained at all times, including maintenance of accountability records showing disposition of input and output documents. (3) All persons whose duties require access to processing and maintenance...

  16. Maintaining Indoor Environmental Quality (IEQ) during Construction and Renovation

    Science.gov (United States)

    ... and Allergies Chemical Safety Construction Safety and Health Emergency Preparedness for Business Occupational Respiratory Disease Surveillance ... Share Compartir Maintaining Indoor Environmental Quality (IEQ) during Construction and ...

  17. Microstructure and properties of novel polarization maintaining fiber

    Institute of Scientific and Technical Information of China (English)

    LI Mei-cheng; LIU Li-hua; XUE Jian-jun; XIAO Tian-peng; LIANG Le-tian; ZHAO Lian-cheng

    2005-01-01

    An improved type of elliptical jacket polarization maintaining fiber was developed by using a modified chemical vapor deposition method with special treatment. Different from conventional elliptical jacket, the shape of the stress jacket was transmuted. The cross-section of fiber consists of 5 layers: substrate, outer cladding, stress jacket, inner cladding and core. The cross sectional component distribution was investigated by electron probe microscopy and energy dispersive spectrum. The finite element method was used to calculate the stress birefringence. Based on the analyses of the microstructure, the technological process is improved. The temperature cycling test of the fiber wound into gyroscope coils was performed. The results show that the fiber possesses superior performance at high and low temperatures compared with other fibers. The high homogeneity is achieved by well-controlled modified chemical vapor deposition process. A homogeneous length of 8 km fiber is obtained. With advantages in homogeneity and length, the fiber has great potential in applications such as fiber gyroscopes, fiber hydrophone and other optical fiber sensors.

  18. Hanford Site guide for preparing and maintaining generator group pollution prevention program documentation

    Energy Technology Data Exchange (ETDEWEB)

    Place, B. G.

    1997-11-25

    This document provides guidance to contractor generator groups for developing and maintaining documentation of Pollution Prevention/Waste. Minimization (P2/WMin) Program activities. The program documentation is intended to demonstrate generator compliance with U.S. Department of Energy (DOE) requirements as well as state and Federal regulations.

  19. How to maintain nuclear competence and knowledge management in Europe

    International Nuclear Information System (INIS)

    In the next decades, the tasks in nuclear activities will remain important in Europe irrespective of the different energy options decided by the Member State Governments. Radiation protection, safe nuclear plant operation and nuclear waste management where existing, rely on highly skilled people. There are serious concerns about their replacement from the coming generation. Reasons for concern occur now in several reports. Knowledge Management has evolved from an information technology buzzword, into a domain with a wide spectrum of practical applications in a rapidly growing number of organizations. In the information society, knowledge management techniques are seen as the decisive means in concentrating and preserving a company's knowledge, offering easy and fast access to this knowledge (particularly the experts 'implicit' knowledge as opposed to 'explicit' documents), ensuring its efficient use, thus keeping up the company's competitiveness. The variety of techniques employed by a knowledge management such as knowledge portals for easy access and navigation of the knowledge, document management systems for administration of arbitrary documents formats, content managers with extended classification, search and retrieval capabilities, yellow pages connecting the knowledge domain with the knowledgeable persons in the field, and inclusion of existing databases might help overcome the difficulties which are foreseen for the near future. As a consequence, the chances and benefits offered by knowledge management in the nuclear field should not be neglected. First projects use are under way in several countries to investigate these aspects. An efficient knowledge management should have those coming from other domains to enter easily into the nuclear sector. In the end, however, successful recruitment of skilled nuclear personnel will depend mostly on the attractiveness of the sector. In view of enlargement of the European Union, a major additional aspect is that all

  20. 49 CFR 1310.2 - Requirement to maintain tariffs.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Requirement to maintain tariffs. 1310.2 Section... BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS TARIFF REQUIREMENTS FOR HOUSEHOLD GOODS CARRIERS § 1310.2 Requirement to maintain tariffs. (a) Except when providing...

  1. 19 CFR 143.6 - Failure to maintain performance standards.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Failure to maintain performance standards. 143.6... maintain performance standards. ABI participants must adhere to the performance requirements and... Support Services Division, of any action to place the participant on probation. The notice...

  2. Evolving Reliability and Maintainability Allocations for NASA Ground Systems

    Science.gov (United States)

    Munoz, Gisela; Toon, T.; Toon, J.; Conner, A.; Adams, T.; Miranda, D.

    2016-01-01

    This paper describes the methodology and value of modifying allocations to reliability and maintainability requirements for the NASA Ground Systems Development and Operations (GSDO) programs subsystems. As systems progressed through their design life cycle and hardware data became available, it became necessary to reexamine the previously derived allocations. This iterative process provided an opportunity for the reliability engineering team to reevaluate allocations as systems moved beyond their conceptual and preliminary design phases. These new allocations are based on updated designs and maintainability characteristics of the components. It was found that trade-offs in reliability and maintainability were essential to ensuring the integrity of the reliability and maintainability analysis. This paper discusses the results of reliability and maintainability reallocations made for the GSDO subsystems as the program nears the end of its design phase.

  3. Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons

    DEFF Research Database (Denmark)

    Bak, Lasse K; Schousboe, Arne; Sonnewald, Ursula;

    2006-01-01

    Glucose is the primary energy substrate for the adult mammalian brain. However, lactate produced within the brain might be able to serve this purpose in neurons. In the present study, the relative significance of glucose and lactate as substrates to maintain neurotransmitter homeostasis was...... was unaffected by the choice of substrate. In conclusion, the present study shows that glucose is a necessary substrate to maintain neurotransmitter homeostasis during synaptic activity and that synaptic activity does not induce an upregulation of lactate metabolism in glutamatergic neurons....

  4. Scientific Opinion on the substantiation of a health claim related to fat-free yogurts and fermented milks complying with the specifications ?fat free?, ?low in sugars?, ?high protein?, ?source of calcium? and ?source of vitamin D? for nutrition claims and reduction of body and visceral fat while maintaining lean body mass in the context of an energy-restricted diet pursuant to Article 13.5 of Regulation (EC No 1924/2006

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2015-01-01

    Full Text Available Following an application from Federación Nacional de Industrias Lácteas (FeNIL, submitted pursuant to Article 13.5 of Regulation (EC No 1924/2006 via the Competent Authority of Spain, the Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver an opinion on the scientific substantiation of a health claim related to fat-free yogurts and fermented milks complying with the specifications “fat free”, “low in sugars”, “high protein”, “source of calcium” and “source of vitamin D” for nutrition claims and reduction of body and visceral fat while maintaining lean body mass in the context of an energy-restricted diet. The food that is the subject of the claim is fat-free yogurts and fermented milks complying with the specifications “fat free”, “low in sugars”, “high protein”, “source of calcium” and “source of vitamin D” for nutrition claims. The Panel considers that fat-free yogurts and fermented milks complying with the specifications “fat free”, “low in sugars”, “high protein”, “source of calcium” and “source of vitamin D” for nutrition claims are sufficiently characterised. The Panel considers that reduction of body and visceral fat mass while maintaining lean body mass in the context of an energy-restricted diet is a beneficial physiological effect. No human intervention studies from which conclusions could be drawn for the scientific substantiation of the claim were provided. The Panel concludes that a cause and effect relationship has not been established between the consumption of fat-free yogurts and fermented milks complying with the specifications “fat free”, “low in sugars”, “high protein”, “source of calcium” and “source of vitamin D” for nutrition claims and reduction of body and visceral fat mass while maintaining lean body mass in the context of an energy-restricted diet.

  5. Silence is Golden with High Probability: Maintaining a Connected Backbone in Wireless Sensor Networks

    OpenAIRE

    Santi, Paolo; Simon, J?nos

    2003-01-01

    Reducing node energy consumption to extend network life- time is a vital requirement in wireless sensor networks. In this paper, we present and analyze the energy consumption of a class of cell-based energy conservation protocols. The goal of our protocols is to alternately turn off/on the transceivers of the nodes, while maintaining a connected backbone of active nodes. The protocols presented in this paper are shown to be optimal, in the sense that they extend the network lifetime by a fact...

  6. Maintain a Healthy State of Mind: High School Students

    Science.gov (United States)

    ... Preparedness and Response Maintain a Healthy State of Mind: High School Students Recommend on Facebook Tweet Share ... died. Having upsetting thoughts or pictures in your mind of what happened. They can pop into your ...

  7. Developing maintainability for fusion power systems. Final report

    International Nuclear Information System (INIS)

    The overall purpose of the study is to identify design features of fusion power reactors which contribute to the achievement of high levels of maintainability. Previous phases evaluated several commercial tokamak reactor design concepts. This final phase compares the maintainability of a tandem mirror reactor (TMR) commercial conceptual design with the most maintainable tokamak concept selected from earlier work. A series of maintainability design guidelines and desirable TMR design features are defined. The effects of scheduled and unscheduled maintenance for most of the reactor subsystems are defined. The comparison of the TMR and tokamak reactor maintenance costs and availabilities show that both reactors have similar costs for scheduled maintenance at 19.4 and 20.8 million dollars annually and similar scheduled downtime availability impacts, achieving approximate availabilities of 79% at optimized maintenance intervals and cost of electricity

  8. ANALYTICAL STUDY OF MAINTAINABILITY MODELS FOR QUALITY EVALUATION

    Directory of Open Access Journals (Sweden)

    Rimmi Saini

    2011-06-01

    Full Text Available The interest in software system is increasing day by day. Dealing with the software systems is a complex task. Software must have some qualities on the basis of which it can be applied to any software system. Every software quality model has some characteristics and sub-characteristics, which affect software quality. In this Paper the main emphasis is given on maintainability characteristics. Every system requires that maintainability measure should be done in early stages of development life-cycle which will help the designers to correct the software, if there is any fault, in early phases of designing. By doing this, cost of the development of software will be reduced. The paper gives the overview of various quality models in which maintainability is described. Paper provides the analysis of maintainability in various quality models.

  9. An Improved Functional Hierarchy Frame Model for System Maintainability

    Institute of Scientific and Technical Information of China (English)

    CHEN Dai-Lin; CHEN Dong-lin; WANG Ru-gen; ZHU Xue-ping

    2003-01-01

    By means of analogy, this paper analyses the present functional hierarchy frame model for system maintainability, and presents an improved model. Practical application indicates that the improved model is visualized, more convenient and perfected over the pervious models.

  10. Coastal Maintained Channels in US waters as of May 2013

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This layer shows coastal channels and waterways that are maintained and surveyed by the U.S. Army Corps of Engineers (USACE). These channels are necessary...

  11. Reliability and maintainability data acquisition in equipment development tests

    International Nuclear Information System (INIS)

    The need for collection of reliability, maintainability, and availability data adds a new dimension to the data acquisition requirements of equipment development tests. This report describes the reliability and maintainability data that are considered necessary to ensure that sufficient and high quality data exist for a comprehensive, quantitative evaluation of equipment and system availability. These necessary data are presented as a set of data collection forms. Three data acquisition forms are discussed: an inventory and technical data form, which is filed by the design engineer when the design is finished or the equipment is received; an event report form, which is completed by the senior test operator at each shutdown; and a maintainability report, which is a collaborative effort between senior operators and lead engineers and is completed on restart. In addition, elements of a reliability, maintainability evaluation program are described. Emphasis is placed on the role of data, its storage, and use in such a program

  12. Allocating SMART Reliability and Maintainability Goals to NASA Ground Systems

    Science.gov (United States)

    Gillespie, Amanda; Monaghan, Mark

    2013-01-01

    This paper will describe the methodology used to allocate Reliability and Maintainability (R&M) goals to Ground Systems Development and Operations (GSDO) subsystems currently being designed or upgraded.

  13. A cryogenic optical feedthrough using polarization maintaining fibers

    Science.gov (United States)

    Nelson, M. J.; Collins, C. J.; Speake, C. C.

    2016-03-01

    Polarization maintaining optical fibers can be used to transmit linearly polarized light over long distances but their use in cryogenic environments has been limited by their sensitivity to temperature changes and associated mechanical stress. We investigate experimentally how thermal stresses affect the polarization maintaining fibers and model the observations with Jones matrices. We describe the design, construction, and testing of a feedthrough and fiber termination assembly that uses polarization maintaining fiber to transmit light from a 633 nm HeNe laser at room temperature to a homodyne polarization-based interferometer in a cryogenic vacuum. We report on the efficiency of the polarization maintaining properties of the feedthrough assembly. We also report that, at cryogenic temperatures, the interferometer can achieve a sensitivity of 8 × 10-10 rad/ √{ Hz } at 0.05 Hz using this feedthrough.

  14. Plant Layout Method Considering Material Handling Cost and Maintainability

    OpenAIRE

    Fujihara, Yutaka; Osaki, Hirokazu

    1997-01-01

    This paper presents a method using simulated annealing(SA) and genetic algorithm(GA) to solve the plant layout problem in which the layout is evaluated by material handling cost and maintainability. In the former study about facility layout problem, it was either the minimization of the objeective function consisting of transport cost or the maximization of the objective function consisting of closeness rating. In this paper, both transport cost and maintainability were included in the object...

  15. ANALYTICAL STUDY OF MAINTAINABILITY MODELS FOR QUALITY EVALUATION

    OpenAIRE

    Rimmi Saini; Sanjay Kumar Dubey; (Dr.) Ajay Rana

    2011-01-01

    The interest in software system is increasing day by day. Dealing with the software systems is a complex task. Software must have some qualities on the basis of which it can be applied to any software system. Every software quality model has some characteristics and sub-characteristics, which affect software quality. In this Paper the main emphasis is given on maintainability characteristics. Every system requires that maintainability measure should be done in early stages of development life...

  16. Maintainability of Functional Reactive Programs in a Telecom Server Software

    OpenAIRE

    Toczé, Klervie; Vasilevskaya, Maria; Sandahl, Patrik; Nadjm-Tehrani, Simin

    2016-01-01

    Functional Reactive Programming (FRP) is claimed to be a good choice for event handling applications. Current object- oriented telecom applications are known to suffer from additional complexity due to event handling code. In this paper we study the maintainability of FRP programs in the tele- com domain compared to traditional object-oriented programming (OOP), with the motivation that higher maintainability increases the service quality and decreases the costs. Two implementations of the sa...

  17. Evaluation of the Maintainability of Object-Oriented Software

    OpenAIRE

    Henry, Sallie M.; Humphrey, Matthew C.; Lewis, John A.

    1990-01-01

    Empirical research is one way of testing software engineering methodologies. Many claims of the advantages of the object oriented paradigm have been made by research. Our work involves empirical projects in an attempt to validate these claims. This paper describes an experiment which compares the maintainability of the two functionally equivalent systems in order to explore the claim that systems developed with object-oriented languages are more easily maintained than those programmed with...

  18. Maintaining Sibling Relationships for Children in Foster and Adoptive Placements

    OpenAIRE

    James, Sigrid; Monn, Amy R.; Palinkas, Lawrence A.; Leslie, Laurel K.

    2008-01-01

    To better understand the nature of sibling relationships among children in foster or adoptive placement and the challenges and processes involved in maintaining these relationships, we conducted an exploratory analysis of data collected from semi-structured interviews with caregivers of 14 foster and adopted children in San Diego County. We identified three patterns of placement histories and living situations which appeared to impact the degree of contact maintained with siblings: (1) childr...

  19. Maintaining dental records: Are we ready for forensic needs?

    Science.gov (United States)

    Astekar, Madhusudan; Saawarn, Swati; Ramesh, Gayathri; Saawarn, Nisheeth

    2011-01-01

    Context: Dental remains are usually the last to get destroyed among body parts after death. They may be useful for personal identification in cases of mass disasters and decomposed unidentified bodies. Dental records may help in the identification of suspects in criminal investigations and in medicolegal cases. Maintenance of dental records is legally mandatory in most of the European and American countries. Unfortunately, the law is not very clear in India, and the awareness is very poor. Aims: To assess the awareness regarding the dental record maintenance among dentists in Rajasthan, to deduce the quality of average dental records kept by them and to evaluate the potential use of their maintained records, in any of forensic or medicolegal cases. Settings and Design: A cross-sectional survey was conducted among 100 dental practitioners of different cities in Rajasthan, India. Materials and Methods: Data were collected through a structured questionnaire, which was responded by the study population in the course of a telephonic interview. The questionnaire addressed on the mode of maintaining dental records in their regular practice. Statistical Analysis Used: The data so gathered were subjected for descriptive analysis. Results: As for knowledge or awareness about maintaining dental records, surprisingly a very low percentile (about 38%) of surveyed dentists maintained records. Sixty-two percent of the dentists were maintaining no records at all. Conclusion: Nonmaintenance or poor quality of records maintained indicates that the dentists in Rajasthan are not prepared for any kind of forensic and medicolegal need if it arises. PMID:22408320

  20. Energy

    International Nuclear Information System (INIS)

    This chapter of the environmental control report deals with the environmental impact of energy production, energy conversion, atomic energy and renewable energy. The development of the energy consumption in Austria for the years 1993 to 1999 is given for the different energy types. The development of the use of renewable energy sources in Austria is given, different domestic heat-systems are compared, life cycles and environmental balance are outlined. (a.n.)

  1. STRATEGIES OF MAINTAINING PROFICIENCY BY TEACHERS OF ENGLISH IN INDONESIA

    Directory of Open Access Journals (Sweden)

    Junaidi Mistar, Alfan Zuhairini

    2011-10-01

    Full Text Available The objectives of the present study are four-fold: (1 to identify the types of strategies to maintain proficiency used by teachers of English in Indonesia, (2 to know the intensity of use of the obtained strategy types, (3 to measure the inter-correlation in the use of the obtained strategy types, and (4 to investigate the effect of proficiency level on the use of maintaining strategies. The subjects were 93 teachers applying for S2 degree in 2010/2011 at the postgraduate program of the Islamic University of Malang. They were given two sets of instrument, a Likert-scale questionnaire of English proficiency maintaining strategies and a TOEFL test. Then, a factor analysis identified nine strategy categories, including language focusing, metacognitive and affective developing, reading and writing activating, language resource utilizing, cognitive processing, culture learning, social communicating, text analyzing, and radio listening strategies. These strategy types explained 63.84% of variances of maintaining strategies and they were used at high level of intensity. Moreover, the use of the nine strategy types were found to be inter-correlated with one another. Finally, no significant effect of proficiency level on strategy use was found, indicating that teachers with different level of proficiency reported using the same strategies of maintaining their proficiency.

  2. Advanced remotely maintainable force-reflecting servomanipulator concept

    International Nuclear Information System (INIS)

    A remotely maintainable force-reflecting servomanipulator concept is being developed at the Oak Ridge National Laboratory as part of the Consolidated Fuel Reprocessing Program. This new manipulator addresses requirements of advanced nuclear fuel reprocessing with emphasis on force reflection, remote maintainability, reliability, radiation tolerance, and corrosion resistance. The advanced servomanipulator is uniquely subdivided into remotely replaceable modules which will permit in situ manipulator repair by spare module replacement. Manipulator modularization and increased reliability are accomplished through a force transmission system that uses gears and torque tubes. Digital control algorithms and mechanical precision are used to offset the increased backlash, friction, and inertia resulting from the gear drives. This results in the first remotely maintainable force-reflecting servomanipulator in the world. 10 references, 4 figures, 1 table

  3. Evaluation of the Software Architecture Styles from Maintainability Viewpoint

    Directory of Open Access Journals (Sweden)

    Gholamreza ShahMohammadi

    2014-01-01

    Full Text Available In the process of software architecture design, different decisions are made that have systemwide impact. An important decision of design stage is the selection of a suitable software architecture style. Lack of investigation on the quantitative impact of architecture styles on software quality attributes is the main problem in using such styles. So, the use of architecture styles in designing is based on the intuition of software developers. The aim of this research is to quantify the impacts of architecture styles on software maintainability. In this study, architecture styles are evaluated based on coupling, complexity and cohesion metrics and ranked by analytic hierarchy process from maintainability viewpoint. The main contribution of this paper is quantification and ranking of software architecture styles from the perspective of maintainability quality attribute at stage of architectural style selection.

  4. STRATEGIES OF MAINTAINING PROFICIENCY BY TEACHERS OF ENGLISH IN INDONESIA

    OpenAIRE

    Junaidi Mistar, Alfan Zuhairini

    2011-01-01

    The objectives of the present study are four-fold: (1) to identify the types of strategies to maintain proficiency used by teachers of English in Indonesia, (2) to know the intensity of use of the obtained strategy types, (3) to measure the inter-correlation in the use of the obtained strategy types, and (4) to investigate the effect of proficiency level on the use of maintaining strategies. The subjects were 93 teachers applying for S2 degree in 2010/2011 at the postgraduate program of the I...

  5. Maintainability design criteria for packaging of spacecraft replaceable electronic equipment.

    Science.gov (United States)

    Kappler, J. R.; Folsom, A. B.

    1972-01-01

    Maintainability must be designed into long-duration spacecraft and equipment to provide the required high probability of mission success with the least cost and weight. The ability to perform repairs quickly and easily in a space environment can be achieved by imposing specific maintainability design criteria on spacecraft equipment design and installation. A study was funded to investigate and define design criteria for electronic equipment that would permit rapid removal and replacement in a space environment. The results of the study are discussed together with subsequent simulated zero-g demonstration tests of a mockup with new concepts for packaging.

  6. The Role of Filtration in Maintaining Clean Heat Exchanger Coils

    Energy Technology Data Exchange (ETDEWEB)

    Li Yang; James E. Braun; Eckhard A. Groll

    2004-06-30

    The main purpose of the study was to investigate the role of filtration in maintaining clean heat exchanger coils and overall performance. Combinations of 6 different levels of filtration (MERV 14, 11, 8, 6, 4, and no filter) and 4 different coils (an eight-row lanced-fin coil, HX8L), (an eight-row wavy-fin coil, HX8W), (a four-row lanced-fin coil, HX4L) and (a two-row lanced-fin coil, HX2L) were tested at 4 different air velocities (1.52, 2.03, 2.54,3.05 m/s (300, 400, 500, 600 ft/min)). The fouled conditions were obtained after injection of 600 grams of ASHRAE standard dust upstream of the filter/coil combination. This magnitude of dust is representative of a year of normal operation for an air conditioning system. The air-side pressure drops of the coils and filters and air-side heat transfer coefficients of the coils were determined from the measurements under the clean and fouled conditions. Depending upon the filter and coil test, the coil pressure drops increased in the range of 6%-30% for an air velocity at 2.54 m/s (500 ft/min). The impact was significantly greater for tests performed without a filter. The largest relative effect of fouling on pressure drop occurs for coils with fewer rows and having lanced fins. Coils with a greater number of rows can hold more dust so that a fixed amount of dust has a relatively smaller impact. The impact of fouling on air-side heat transfer coefficients was found to be relatively small. In some cases, heat transfer was actually enhanced due to additional turbulence caused by the presence of dust. The experimental results for pressure drops and heat transfer coefficients were correlated and the correlations were implemented within computer models of prototypical rooftop air conditioners and used to evaluate the impact of fouling on cooling capacity and EER. The equipment cooling capacity is reduced with fouling primarily because of a decrease in air flow due to the increase pressure drop rather than due to changes in h

  7. Graphene incorporated Q-switching of a polarization-maintaining Yb-doped fiber laser

    International Nuclear Information System (INIS)

    Environmentally-stable, all-polarization-maintaining Q-switching ytterbium-doped fiber laser was demonstrated using graphene as saturable absorber. By optically driving deposition of graphene onto the fiber connector, the saturable absorber is fabricated and inserted into the laser cavity to construct the Q-switching fiber laser. The maximum average output power of 15.6 mW at a repetition rate of 110 kHz, which corresponds to a single pulse energy of 141.8 nJ, was achieved. They are the maximum average output power and the highest single pulse energy reported so far for graphene Q-switched fiber lasers

  8. Energy

    CERN Document Server

    Foland, Andrew Dean

    2007-01-01

    Energy is the central concept of physics. Unable to be created or destroyed but transformable from one form to another, energy ultimately determines what is and isn''t possible in our universe. This book gives readers an appreciation for the limits of energy and the quantities of energy in the world around them. This fascinating book explores the major forms of energy: kinetic, potential, electrical, chemical, thermal, and nuclear.

  9. Alternative oxidase: a respiratory electron transport chain pathway essential for maintaining photosynthetic performance during drought stress.

    Science.gov (United States)

    Vanlerberghe, Greg C; Martyn, Greg D; Dahal, Keshav

    2016-07-01

    Photosynthesis and respiration are the hubs of energy metabolism in plants. Drought strongly perturbs photosynthesis as a result of both diffusive limitations resulting from stomatal closure, and in some cases biochemical limitations that are associated with a reduced abundance of key photosynthetic components. The effects of drought on respiration, particularly respiration in the light (RL ), are less understood. The plant mitochondrial electron transport chain includes a non-energy conserving terminal oxidase called alternative oxidase (AOX). Several studies have shown that drought increases AOX transcript, protein and maximum capacity. Here we review recent studies comparing wild-type (WT) tobacco to transgenic lines with altered AOX protein amount. Specifically during drought, RL was compromised in AOX knockdown plants and enhanced in AOX overexpression plants, compared with WT. Significantly, these differences in RL were accompanied by dramatic differences in photosynthetic performance. Knockdown of AOX increased the susceptibility of photosynthesis to drought-induced biochemical limitations, while overexpression of AOX delayed the development of such biochemical limitations, compared with WT. Overall, the results indicate that AOX is essential to maintaining RL during drought, and that this non-energy conserving respiration maintains photosynthesis during drought by promoting energy balance in the chloroplast. This review also outlines several areas for future research, including the possibility that enhancement of non-energy conserving respiratory electron sinks may be a useful biotechnological approach to increase plant performance during stress. PMID:27080742

  10. Maintaining Functional Safety under an Intentional Electromagnetic Interference (IEMI) Attack

    OpenAIRE

    Ängskog, Per; Oakes, Ben

    2013-01-01

    The importance of protection against IEMI effects in civilian applications is growing rapidly as more and more societal infrastructure is equipped with electronic devices. This paper discusses methods to help maintaining functional safety in the event of an IEMI attack. QC 20160104

  11. Small mammal herbivory: Feedbacks that help maintain desertified ecosystems

    Science.gov (United States)

    We tested the hypothesis that herbivores contribute to feedbacks maintaining arid ecosystems in a degraded state. We studied small mammal herbivory on a subshrub, broom snakeweed (Gutierrezia sarothrae), and perennial grasses at three sites: (1) ungrazed black grama (Bouteloua eriopoda) grassland; (...

  12. Genetic and somatic effects in animals maintained on tritiated water

    International Nuclear Information System (INIS)

    The possible genetic (dominant lethal mutations (DLM) and cytogenetic changes in the regenerating liver) and somatic (hematopoietic stem cell changes, growth and nonspecific life time shortening) effects in mice maintained on tritiated water (HTO) over two generations was investigated. Results to date are summarized

  13. Maintaining of the demineralized water quality in storage tanks

    International Nuclear Information System (INIS)

    Two processes for maintaining the quality of the mineralized water in storage tanks are considered. A slight overpressure of nitrogen can be created above the water, or the air flowing in the tank can be cleaned by passing it through a soda-containing lime filter

  14. Genetic and somatic effects in animals maintained on tritiated water

    Energy Technology Data Exchange (ETDEWEB)

    Carsten, A.L.; Brooks, A.; Commerford, S.L.; Cronkite, E.P.

    1981-01-01

    The possible genetic (dominant lethal mutations (DLM) and cytogenetic changes in the regenerating liver) and somatic (hematopoietic stem cell changes, growth and nonspecific life time shortening) effects in mice maintained on tritiated water (HTO) over two generations was investigated. Results to date are summarized. (ACR)

  15. Maintaining ecological soil functions - techniques in organic farming systems

    OpenAIRE

    Beste, Andrea

    2000-01-01

    The ecological soil functions (e.g. habitat and living space, production and utilization, ecological regulation) have to be taken into account and maintained by farming systems. Organic farming systems can provide for this by using suitable crop rotations, manure management methods and tillage techniques.

  16. Keeping Ourselves Well: Strategies for Promoting and Maintaining Counselor Wellness

    Science.gov (United States)

    Cummins, Paige N.; Massey, Linda; Jones, Anita

    2007-01-01

    This article describes challenges to wellness that counselors face when working with clients. Autobiographical reflections are used to illustrate the personal nature of some of these challenges and how this affects counselor effectiveness and wellness. Additionally, assessment measures and theoretical models for promoting and maintaining wellness…

  17. Beijing's Convention and Exhibition Industry Maintains Good Momentum

    Institute of Scientific and Technical Information of China (English)

    Xiong Jiuling

    2011-01-01

    @@ In recent years, Beijing's conven-tion and exhibition industry has maintained a good development momentum with expanding scale and improving facilities, becoming an inseparable part of the city's modern service sector.The development of the convention and exhibition industry has played an active role in perfecting the capital's functions, optimizing the industrial structure and enhancing the city's radiation capabilities.

  18. [Maintaining the proper distance for nurses working in the home].

    Science.gov (United States)

    Estève, Sonia

    2016-01-01

    Health professionals must be able to respond to many different situations which require technical knowledge and self-control. Particularly when working in the patient's home, nurses must know how to maintain a proper distance to protect themselves from burnout. In this respect, the practice analysis constitutes an adapted support tool. PMID:27393988

  19. Impact of Agile Software Development Model on Software Maintainability

    Science.gov (United States)

    Gawali, Ajay R.

    2012-01-01

    Software maintenance and support costs account for up to 60% of the overall software life cycle cost and often burdens tightly budgeted information technology (IT) organizations. Agile software development approach delivers business value early, but implications on software maintainability are still unknown. The purpose of this quantitative study…

  20. A Swarm Intelligent Algorithm Based Route Maintaining Protocol for Mobile Sink Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Xiaoming Wu

    2015-01-01

    Full Text Available Recent studies have shown that mobile sink can be a solution to solve the problem that energy consumption of sensor nodes is not balanced in wireless sensor networks (WSNs. Caused by the sink mobility, the paths between the sensor nodes and the sink change frequently and have profound influence on the lifetime of WSN. It is necessary to design a protocol that can find efficient routings between the mobile sink and nodes but does not consume too many network resources. In this paper, we propose a swarm intelligent algorithm based route maintaining protocol to resolve this issue. The protocol utilizes the concentric ring mechanism to guide the route researching direction and adopts the optimal routing selection to maintain the data delivery route in mobile sink WSN. Using the immune based artificial bee colony (IABC algorithm to optimize the forwarding path, the routing maintaining protocol could find an alternative routing path quickly and efficiently when the coordinate of sink is changed in WSN. The results of our extensive experiments demonstrate that our proposed route maintaining protocol is able to balance the network traffic load and prolong the network lifetime.

  1. Mechanical properties of different types of space maintainers

    Science.gov (United States)

    Beldiman, M.-A.; Mârţu, I.; Leiţoiu, B.; Luchian, I.; Lupescu, O.; Bârcă, E. S.

    2015-11-01

    Currently, inside the oral cavity, the dental space maintainers are subjected to forces exerted on them when performing various functions; therefore, it is important to know how each of these mechanisms behave and respond to forces that are applied directly to them. The mechanical properties of the materials used in dentistry are defined by a set of characteristics representing the behaviour of their particular working conditions and it is qualitatively expressed by a number of parameters.The study aimed to determine the pressing force that can be taken by four 4 types of space maintainers frequently used in practice - fixed and removable, applied on four samples realized with human teeth extracted for orthodontic purposes. Static tests were carried out on a machine type short WDW-5 EC with a maximum force of 5 kN and a loading speed of 5 mm/min by a special testing machine, with an innovative appliance; data recording was automatically performed, using a computer with a special program that present the specific diagrams. Experimental determinations included the following aspects: to determine the maximum force that can be supported by each sample, and to observe the deformations. The values obtained indicate that the best option in terms of behavior under the conditions specified is the removable appliance, and the less functional version is the fixed space maintainer using brackets. According to tests conducted, the fracture strength was found to be more important for fixed space maintainers (band and loop, for example) so, in practice is using more frequent these types of space maintainers.

  2. Fertilization test performance using Arbacia punctulata maintained in static culture

    Energy Technology Data Exchange (ETDEWEB)

    Serbst, J.R. [Environmental Protection Agency, Narragansett, RI (United States). Environmental Research Lab.; Wright, L.; Sheehan, C.V.; Fitzpatrick, K. [Science Applications International Corp., Narragansett, RI (United States)

    1995-12-31

    The sea urchin fertilization test using the Atlantic urchin, Arbacia punctulata, is widely utilized in evaluating toxicity of receiving waters and effluents as part of the NPDES program. While this species is easily maintained in uncontaminated, flow-through seawater systems, laboratories without access to flowing seawater either obtain new urchins for each test or maintain populations in static cultures. This study was conducted to assess test success and reproducibility of fertilization tests conducted using urchins maintained in separate-sex, static, temperature-controlled aquaria containing filtered natural seawater. Test performance was evaluated by periodically conducting the standard sea urchin fertilization test (EPA 600/4-87-028) using a common reference toxicant, sodium dodecyl sulfate (SDS) Thirteen tests were conducted between September 1993 and May 1994 using one population of urchins, and five tests were conducted between June and December 1994 with a second population of urchins. Test success was 100% (control fertilization > 50%) with a control fertilization mean of 96.4% (S.D. = 3.3). There were no differences between mean EC{sub 50} values calculated for each set of tests (p < 0.05). The running mean value for toxicity was 7.1 mg/L (S.D. = 1.26) for 18 tests, with a CV of 17.7%, comparing favorably with values generated using urchins maintained in flowing seawater. The running mean value for toxicity in these tests was 2.4 mg/L (S.D. = 0.9) for 18 tests conducted between November 1987 and July 1989 (ASTM STP 1124). Data from all urchin tests were used to construct a control chart defining normal ranges for SDS toxicity. This study demonstrated that fertile, adult sea urchins can produce consistent toxicity responses with low variability while being maintained in static, temperature regulated culture facilities.

  3. Energy

    CERN Document Server

    Robertson, William C

    2002-01-01

    Confounded by kinetic energy? Suspect that teaching about simple machines isn t really so simple? Exasperated by electricity? If you fear the study of energy is beyond you, this entertaining book will do more than introduce you to the topic. It will help you actually understand it. At the book s heart are easy-to-grasp explanations of energy basics work, kinetic energy, potential energy, and the transformation of energy and energy as it relates to simple machines, heat energy, temperature, and heat transfer. Irreverent author Bill Robertson suggests activities that bring the basic concepts of energy to life with common household objects. Each chapter ends with a summary and an applications section that uses practical examples such as roller coasters and home heating systems to explain energy transformations and convection cells. The final chapter brings together key concepts in an easy-to-grasp explanation of how electricity is generated. Energy is the second book in the Stop Faking It! series published by NS...

  4. End of living: maintaining a lifeworld during terminal illness.

    Science.gov (United States)

    Wrubel, Judith; Acree, Michael; Goodman, Steffanie; Folkman, Susan

    2009-12-01

    The narrative responses of 32 people with AIDS or cancer with survival prognoses of 6 months to a year to monthly interview questions about their daily lives were analysed with a team-based qualitative methodology. Two groups emerged: (a) a Maintained Lifeworld Group characterised by one or more of the following: continued engagement with family, friends, and community; the ability to relinquish untenable goals and substitute new, realistic ones; engagement in spirituality and a spiritual practice; and, (b) a Lifeworld Interrupted Group characterised by one or more of the following: relocation just before or during the study, cognitive impairment, commitment to untenable goals, ongoing substance abuse. Understanding how people with a terminal illness can maintain a lifeworld and experience well-being while also managing the physical challenges of their illness could help inform the support offered by professional and family caregivers to improve care recipients' quality of life. PMID:20204990

  5. Polarization maintaining linear cavity Er-doped fiber femtosecond laser

    Science.gov (United States)

    Jang, Heesuk; Jang, Yoon-Soo; Kim, Seungman; Lee, Keunwoo; Han, Seongheum; Kim, Young-Jin; Kim, Seung-Woo

    2015-10-01

    We present a polarization-maintaining (PM) type of Er-doped fiber linear oscillator designed to produce femtosecond laser pulses with high operational stability. Mode locking is activated using a semiconductor saturable absorber mirror (SESAM) attached to one end of the linear PM oscillator. To avoid heat damage, the SESAM is mounted on a copper-silicon-layered heat sink and connected to the linear oscillator through a fiber buffer dissipating the residual pump power. A long-term stability test is performed to prove that the proposed oscillator design maintains a soliton-mode single-pulse operation without breakdown of mode locking over a week period. With addition of an Er-doped fiber amplifier, the output power is raised to 180 mW with 60 fs pulse duration, from which an octave-spanning supercontinuum is produced.

  6. Maintaining students’ Speaking Fluency through Exhibition Examination in Sociolinguistic Studies

    Directory of Open Access Journals (Sweden)

    Khusnul Qhotimah Yuliatuty

    2013-07-01

    Full Text Available Using exhibition for the final project in Sociolinguistic study is really interesting for Universitas Siswa Bangsa Internasional students, especially for 2011 English Department students. Exhibition becomes interesting because this is the new thing to conduct the final project for English Department students’ cohort 2011 at Universitas Siswa Bangsa Internasional. The lecturer divides the students into pairs and each pairs should master one content or topic in Sociolinguistic study.  The students will do the exhibition about the topic that they get in a pairs. The lecturer also gives the students rubric sheet to fill by the visitors. The exhibition will make the students prepare themselves well because they will face many questions about the content which will be delivered by them. Beside, this exhibition also maintains students’ fluency in speaking English because they will explain and answer the questions from visitors with English. This paper tries to focus on how exhibition examination can maintain students’ fluency in speaking English.

  7. Acquiring and maintaining a normal oral microbiome: current perspective

    OpenAIRE

    Egija eZaura; Nicu, Elena A; Krom, Bastiaan P.; Bart JF Keijser

    2014-01-01

    The oral microbiota survives daily physical and chemical perturbations from the intake of food and personal hygiene measures, resulting in a long-term stable microbiome. Biological properties that confer stability in the microbiome are important for the prevention of dysbiosis – a microbial shift towards a disease, e.g., periodontitis or caries. Although processes that underlie oral diseases have been studied extensively, processes involved in maintaining of a normal, healthy microbiome are p...

  8. Acquiring and maintaining a normal oral microbiome: current perspective

    OpenAIRE

    Zaura, Egija; Nicu, Elena A; Krom, Bastiaan P.; Keijser, Bart J. F.

    2014-01-01

    The oral microbiota survives daily physical and chemical perturbations from the intake of food and personal hygiene measures, resulting in a long-term stable microbiome. Biological properties that confer stability in the microbiome are important for the prevention of dysbiosis—a microbial shift toward a disease, e.g., periodontitis or caries. Although processes that underlie oral diseases have been studied extensively, processes involved in maintaining of a normal, healthy microbiome are poor...

  9. Comprehensive Complexity-Based Failure Modeling for Maintainability and Serviceability

    OpenAIRE

    Meselhy, K. T.; ElMaraghy, H. A.; ElMaraghy, W. H.

    2009-01-01

    Failures are the primary triggers for repair and maintenance actions. A clear definition of failure events is important in order to improve maintainability and serviceability. A comprehensive complexity-based mathematical definition of failure is introduced. The applicability of the developed failure model to different complexity definitions is discussed. A new metric is introduced to capture the change in complexity associated with function degradation. A case study is present...

  10. Lhx2 Maintains Stem Cell Character in Hair Follicles

    OpenAIRE

    Rhee, Horace; Polak, Lisa; Fuchs, Elaine

    2006-01-01

    During embryogenesis, stem cells are set aside to fuel the postnatal hair cycle and repair the epidermis after injury. To define how hair follicle stem cells are specified and maintained in an undifferentiated state, we developed a strategy to isolate and transcriptionally profile embryonic hair progenitors in mice. We identified Lhx2 as a transcription factor positioned downstream of signals necessary to specify hair follicle stem cells, but upstream from signals required to drive activated ...

  11. Rewarding Peer Reviewers: Maintaining the Integrity of Science Communication

    OpenAIRE

    Gasparyan, Armen Yuri; Gerasimov, Alexey N.; Voronov, Alexander A.; Kitas, George D.

    2015-01-01

    This article overviews currently available options for rewarding peer reviewers. Rewards and incentives may help maintain the quality and integrity of scholarly publications. Publishers around the world implemented a variety of financial and nonfinancial mechanisms for incentivizing their best reviewers. None of these is proved effective on its own. A strategy of combined rewards and credits for the reviewers1 creative contributions seems a workable solution. Opening access to reviews and ass...

  12. Maintaining compassion and preventing compassion fatigue: a practical guide.

    Science.gov (United States)

    Baverstock, Anna Charlotte; Finlay, Fiona Olwen

    2016-08-01

    Compassion is innate in us as human beings. Compassion can be defined as a deep awareness of the suffering of another individual, coupled with the wish to relieve it. It has been increasingly topical, recently, in situations where an apparent breathtaking absence of compassion has allowed great harm to come to patients. So, how do we sustain compassion and prevent this loss? Central to our ability to maintain compassion is how we look after ourselves and those in our teams. PMID:26510446

  13. Maintaining NASTRAN :the politics and technics of aerospace computing

    OpenAIRE

    Hu, Minghui

    1995-01-01

    This thesis describes a process of how NASA maintained the NASTRAN (NASA Structural Analysis) computer program. Chapter one addresses my theoretical concern and suggests to learn from both critical theorists and social constructivists. Chapters Two and Three tell the story of NASA and NASTRAN, a computer program developed by NASA for solving problems of airframes and space structures. The story of NASA and NASTRAN demonstrates a structural imbalance between social groups of NAS...

  14. Maintaining Customer Loyalty : Case company: Industrail Securities Ltd (China)

    OpenAIRE

    Zhang, Wenqing

    2010-01-01

    The purpose of this thesis is to investigate how customer relationship management can be applied in maintaining customer loyalty. The study will assist the case company to find the way to develop a long-term relationship with existing customers. The better relationship with customers, the higher customer loyalty will be obtained. The theoretical background of the thesis begins with general view of customer relationship management, which embodies the concept of managing customer relations...

  15. Creating, Maintaining and Managing an Information Security Culture

    OpenAIRE

    Fagerström, Alex

    2013-01-01

    In the last decade a new threat to information security within an organisation has risen: data loss by personnel mistakes or maliciousness now rank among the top threats to a company's data. By creating a strong information security culture, the management can reduce the risk of data loss. This thesis investigates how to create, maintain and manage an information security culture. Literature analysis, interviews with management members at KPMG, the company for which this thesis was written, a...

  16. Maintaining High-Level Focus on Nuclear Security

    OpenAIRE

    Fitzpatrick, Mark; Pandza, Jasper

    2012-01-01

    This paper explores how nuclear security can be maintained at the top of the international agenda following the 2012 Nuclear Security Summit in Seoul and the third summit to be held in 2014 in the Netherlands. The attention of senior government officials may be vital to catalyzing the implementation of national nuclear security commitments. But continuing the summit process beyond 2014 requires finding novel topics that capture world leaders’ attention and willingness to making the necessary ...

  17. How can Indonesia maintain creditworthiness and noninflationary growth ?

    OpenAIRE

    Ahmed, Sadiq; Chhibber, Ajay

    1989-01-01

    Despite external shocks, Indonesia has maintained creditworthiness through swift adjustment. Indonesia's flexible economic management and clear policy signals have lent stability to the economy, in contrast to the stop and go reforms, uncertainty, and constant debt renegotiations in many high debt countries. The authors use an econometrically estimated macroeconomic model to analyze open economy adjustment in Indonesia - particularly the interaction between the exchange rate, the interest rat...

  18. Knowledge management: knowledge and competence maintaining; problematics; Fast reactor example

    International Nuclear Information System (INIS)

    In this expose are examined two representative aspects, with a first part reserved to the general problematics of the knowledge and competence maintaining as it looks at Framatome, in its activities of pressurized water boiler supplier (PWR) and as provider of nuclear services, and a second part treating the solutions used by the different actors intervening in fast neutrons reactors, that is to say, the Cea, Framatome and EDF. (N.C.)

  19. Maintaining Adherence Programme: evaluation of an innovative service model

    OpenAIRE

    Lewis, Llewellyn; O'Keeffe, Christine; Smyth, Ian; Mallalieu, Judi; Baldock, Laura; Oliver, Sam

    2016-01-01

    Aims and method The Maintaining Adherence Programme (MAP) is a new model of care for patients with schizophrenia, schizoaffective disorder and bipolar affective disorder which aims to encourage adherence and prevent relapse. This evaluation, conducted by retrospective and prospective data collection (including patient questionnaires and staff interviews), aimed to describe MAP's impact on healthcare resource use, clinical measures and patient and staff satisfaction, following its implementati...

  20. Human Sclera Maintains Common Characteristics with Cartilage throughout Evolution

    OpenAIRE

    Yuko Seko; Noriyuki Azuma; Yoriko Takahashi; Hatsune Makino; Toshiyuki Morito; Takeshi Muneta; Kenji Matsumoto; Hirohisa Saito; Ichiro Sekiya; Akihiro Umezawa

    2008-01-01

    BACKGROUND: The sclera maintains and protects the eye ball, which receives visual inputs. Although the sclera does not contribute significantly to visual perception, scleral diseases such as refractory scleritis, scleral perforation and pathological myopia are considered incurable or difficult to cure. The aim of this study is to identify characteristics of the human sclera as one of the connective tissues derived from the neural crest and mesoderm. METHODOLOGY/PRINCIPAL FINDINGS: We have dem...

  1. Maintaining the Brain: Insight into Human Neurodegeneration From Drosophila Mutants

    OpenAIRE

    Lessing, Derek; Bonini, Nancy M.

    2009-01-01

    The fruit fly Drosophila melanogaster has brought significant advances to research in neurodegenerative disease, notably in the identification of genes that are required to maintain the structural integrity of the brain, defined by recessive mutations that cause adult-onset neurodegeneration. Here, we survey these genes in the fly and classify them according to five key cell biological processes. Over half of these genes have counterparts in mouse or human that are also associated with neurod...

  2. Maintaining Interoperability in a Target-Rich Environment

    OpenAIRE

    Ng, Mei Ling Venessa

    2012-01-01

    Achieving interoperability in a net-centric environment is fundamental to maximizing the potential of information sharing and effective use of resources in military operations. With the increasing reliance on unmanned platforms worldwide, there is a need to study the limitations of existing Command and Control (C2) Systems in dealing with the increasing number of objects. More processing power would be required to achieve or maintain a certain level of efficiency and effectiveness of the C2 s...

  3. Strategies for maintaining penile size following penile implant

    OpenAIRE

    Lee, King Chien Joe; Gerald B Brock

    2013-01-01

    Introduction Loss of penile size is a common complaint that can negatively affect patient satisfaction rates following successful penile prosthetic implant surgery. Objective The aim of this review is to describe the various strategies that have been used to maintain penile length or girth after the insertion of a penile prosthetic implant. Methods An extensive systematic literature review was performed, based on a search of the PUBMED database for articles published between 2002 to 2012. The...

  4. Catecholamine-induced excitation of nociceptors in sympathetically maintained pain.

    Science.gov (United States)

    Jørum, Ellen; Ørstavik, Kristin; Schmidt, Roland; Namer, Barbara; Carr, Richard W; Kvarstein, Gunnvald; Hilliges, Marita; Handwerker, Hermann; Torebjörk, Erik; Schmelz, Martin

    2007-02-01

    Sympathetically maintained pain could either be mediated by ephaptic interactions between sympathetic efferent and afferent nociceptive fibers or by catecholamine-induced activation of nociceptive nerve endings. We report here single fiber recordings from C nociceptors in a patient with sympathetically maintained pain, in whom sympathetic blockade had repeatedly eliminated the ongoing pain in both legs. We classified eight C-fibers as mechano-responsive and six as mechano-insensitive nociceptors according to their mechanical responsiveness and activity-dependent slowing of conduction velocity (latency increase of 0.5+/-1.1 vs. 7.1+/-2.0 ms for 20 pulses at 0.125 Hz). Two C-fibers were activated with a delay of several seconds following strong endogenous sympathetic bursts; they were also excited for about 3 min following the injection of norepinephrine (10 microl, 0.05%) into their innervation territory. In these two fibers, a prolonged activation by injection of low pH solution (phosphate buffer, pH 6.0, 10 microl) and sensitization of their heat response following prostaglandin E2 injection were recorded, evidencing their afferent nature. Moreover, their activity-dependent slowing was typical for mechano-insensitive nociceptors. We conclude that sensitized mechano-insensitive nociceptors can be activated by endogenously released catecholamines and thereby may contribute to sympathetically maintained pain. No evidence for ephaptic interaction between sympathetic efferent and nociceptive afferent fibers was found. PMID:16997471

  5. Reliability, availability, and maintainability: a key issue for ELTs

    Science.gov (United States)

    Ansorge, Wolfgang R.

    2006-06-01

    Hundreds of mirror segment, thousands of high precision actuators, highly complex mechanical, hydraulic, electrical and other technology subsystems, and extremely sophisticated control systems: an ELT system consists of millions of individual parts and components each of them may fail and lead to a partial or complete system breakdown. Component and system reliability does not only influence the acquisition costs of a product, it also defines the necessary maintenance work and the required logistic support. Taking the long operational life time of an ELT into account, reliability and maintainability are some of the main contributors to the system life cycle costs. Reliability and maintainability are key characteristics of any product and have to be designed into it from the early beginning; they can neither be tested into a product nor introduced by numerous maintenance activities. This presentation explains the interconnections between Reliability, Availability, Maintainability and Safety (RAMS) and outlines the necessary RAMS and Reliability Centered Maintenance (RCM) processes and activities during the entire life cycle of an ELT and an ELT instrument from the initial planning to the eventual disposal phase.

  6. Improved reliability, maintainability and safety through elastomer upgrading

    International Nuclear Information System (INIS)

    Equipment in nuclear plants has historically contained whatever elastomer each component supplier traditionally used for corresponding non-nuclear service. The resulting proliferation of elastomer compounds, many of which are far from optimal for the service conditions (e.g., pressure, temperature, radiation, etc.), has multiplied the costs to provide station reliability, maintainability and safety. Cost-effective improvements are being achieved in CANDU plants by upgrading and standardizing on a handful of high performing elastomer compounds. These upgraded materials offer significant gains in service life over the materials they replace (often by factors of 2 or more). This rationalization of elastomer compounds also facilitates the EQ process for safety-related equipment. Detailed test data on aging is currently being generated for these specific elastomers, encompassing the conditions and media (air, water, oil) common in CANDU service. Two key elements characterize this testing. First, each result is specific to the compound used in the test, and second, it is specific to the tested failure mode (e.g., compression set, extrusion, fracture, etc.). Having fewer, but more thoroughly tested compounds, avoids the penalty (associated with poorly characterized materials) of having to replace parts prematurely because of conservatism, while maintaining safe, reliable service. This paper provides an overview of this approach covering: the benefits of compound rationalization; and the how and why of establishing relevant failure criteria; appropriate quality assurance to maintain EQ; procurement, storage and handling guidelines; and monitoring and predicting in-service degradation. (author)

  7. The importance of maintainability in maintenance cost management

    International Nuclear Information System (INIS)

    This paper provides specific examples and results from ongoing projects at Power Plants, and for offshore oil platforms. The paper describes the vital role maintainability has on plant availability. How the application of equipment maintainability principles, if addressed using state of the art computer tools and advanced business processes can bring annual return on investment results as high as 15 to 1. The maintenance process of today and for the future must provide for high plant availability at the lowest possible cost. The high cost of obtaining equipment reliability levels necessary to meet required availability demands has not proved to be sustainable. Therefore new business decision processes that address equipment failures as part of the maintenance process have been developed. Repair costs require that equipment failures be selective and controlled so that a high level of safety and plant availability is assurance. This can only be accomplished by the use of advanced computer tools in the hands of well trained maintenance-engineering specialist. The relationship between Reliability Centered Maintenance (RCM), Condition Directed Planned Maintenance (CDPM), and maintainability is also presented

  8. Hybrid-Based Maintainability Impact Analysis for Evolving Systems

    Directory of Open Access Journals (Sweden)

    Samer I. Mohamed

    2009-01-01

    Full Text Available Software maintenance becomes an integral part of software life cycle and constitutes the most important fraction of the total cost of the software lifecycle. Around 50-80 percent of the total lifecycle cost is consumed by maintenance for evolving system. Thus systems with poor maintainability are difficult to modify and require more cost to maintain. This difficulty arises from the impact of the system components where the new requirements/goals will be implemented. These new goals will result in modification of existing components and creation of new components. In this paper, we present the foundation for a new Hybrid-Based Maintainability Impact Analysis (HBMIA methodology for assessing the impact of the new goals to be selected for implementation on the system new and existing components. (HBMIA uses not only the system history but it also gets benefit from the expert?s experience. (HBMIA balances between the system historical data and experts data based on the organization? maturity and experts experience for system components. A case study is performed to demonstrate the added value of the proposed (HBMIA.

  9. Effects of mazindol on behavior maintained or occasioned by cocaine.

    Science.gov (United States)

    Mansbach, R S; Balster, R L

    1993-01-01

    The effects of mazindol, cocaine and D-amphetamine were studied in rhesus monkeys trained to self-administer cocaine, and in rats and squirrel monkeys trained to discriminate cocaine from saline. Non-contingent intravenous drug injections were administered to monkeys responding under a session consisting of a 5-min period during which lever-pressing produced food reinforcement and a 60-min session in which responding produced i.v. cocaine infusions (10 or 33 micrograms/kg per infusion). Acute i.v. injections of cocaine (0.1-1.7 mg/kg), D-amphetamine (0.1-1 mg/kg) and the dopamine re-uptake inhibitor mazindol (0.03-0.56 mg/kg) given 5 min before the session decreased self-administration of cocaine, but also decreased rates of behavior maintained by the presentation of food. In both rats and squirrel monkeys trained to discriminate cocaine from saline in a two-lever, food-maintained procedure, mazindol, cocaine and D-amphetamine substituted for cocaine in a dose-related manner. Despite a lack of selectivity to decrease cocaine self-administration as compared to behavior maintained by food, the present data provide some rationale for further consideration of mazindol as a potential pharmacotherapy for stimulant abuse, due to its relatively low abuse liability and cocaine-like discriminative stimulus effects. PMID:8436063

  10. Maintaining Students’ Involvement in a Math Lecture Using Countdown Timers

    Directory of Open Access Journals (Sweden)

    Ann Krizzel A. Aban

    2015-12-01

    Full Text Available Involving students in a lecture is an important but not an easy task that every lecturer must encourage. This task becomes even greater in a math class that is composed of eighty to a hundred sixty students. In 2007, the University of the Philippines Los Baños (UPLB started offering some of its basic math courses in lecture-recitation set-up. This shift and many other factors drove most math instructors of UPLB to widely use presentation software, such as the PowerPoint (PPT, to deliver their lectures. The non-stop use of these softwares, however, seems to have negative effects on the students when it comes to maintaining their involvement in a lecture discussion for they tend to be more passive spectators. On the other hand, adding countdown timers strategically on some parts of the discussion seems to lessen such negative effects. This study determined the effectiveness of using countdown timers in maintaining students’ involvement in a lecture of MATH 27 (Analytic Geometry and Calculus II, a course in UPLB commonly taken by sophomore students. Results show that the effectiveness of countdown timers, as perceived by the students, is independent to students’ genders and degree programs, but is dependent to the colleges where the students belong to. Also, some effects of countdown timers are significantly correlated to various data from students’ profiles. It was concluded in the study that the use of countdown timers is effective in maintaining student’s involvement in MATH 27 lectures and might also be useful in other math lecture classes

  11. Maintaining Traceability in an Evolving Distributed Computing Environment

    Science.gov (United States)

    Collier, I.; Wartel, R.

    2015-12-01

    The management of risk is fundamental to the operation of any distributed computing infrastructure. Identifying the cause of incidents is essential to prevent them from re-occurring. In addition, it is a goal to contain the impact of an incident while keeping services operational. For response to incidents to be acceptable this needs to be commensurate with the scale of the problem. The minimum level of traceability for distributed computing infrastructure usage is to be able to identify the source of all actions (executables, file transfers, pilot jobs, portal jobs, etc.) and the individual who initiated them. In addition, sufficiently fine-grained controls, such as blocking the originating user and monitoring to detect abnormal behaviour, are necessary for keeping services operational. It is essential to be able to understand the cause and to fix any problems before re-enabling access for the user. The aim is to be able to answer the basic questions who, what, where, and when concerning any incident. This requires retaining all relevant information, including timestamps and the digital identity of the user, sufficient to identify, for each service instance, and for every security event including at least the following: connect, authenticate, authorize (including identity changes) and disconnect. In traditional grid infrastructures (WLCG, EGI, OSG etc.) best practices and procedures for gathering and maintaining the information required to maintain traceability are well established. In particular, sites collect and store information required to ensure traceability of events at their sites. With the increased use of virtualisation and private and public clouds for HEP workloads established procedures, which are unable to see 'inside' running virtual machines no longer capture all the information required. Maintaining traceability will at least involve a shift of responsibility from sites to Virtual Organisations (VOs) bringing with it new requirements for their

  12. Maintaining dignity. The perspective of nursing home residents

    DEFF Research Database (Denmark)

    Høy, Bente

    2014-01-01

    used to understand the meaning of the narrated text. Findings. The residents’ experiences revealed one main theme and seven sub-themes contributing to maintain dignity. The overall theme was: Coping with vulnerability and the subthemes were: Attention and care for basic needs; preserving a positive......Purpose. The overall purpose of this cross-country Nordic study was to gain further knowledge about dignity in nursing homes and the circumstances which may have an impact on it. The aim of this part of the study is to present the results, exploring nursing home residents’ experiences on how...

  13. Reliability of maintained systems under a semi-Markov setting

    International Nuclear Information System (INIS)

    A semi-Markov setting is considered in order to study the main dependability measures of a repairable continuous time system under the hypothesis that the evolution in time of its components is described by a continuous time semi-Markov process. Moreover, the main dependability measures of a periodically maintained system are studied. Finally, all the above systems are compared with the corresponding Markov systems where the general repair time distribution is replaced by the exponential distribution with the same mean which is the most commonly used approximation of the original system in practice

  14. The Importance of Maintaining Protected Zone Status against Bemisia tabaci.

    Science.gov (United States)

    Cuthbertson, Andrew G S; Vänninen, Irene

    2015-01-01

    The sweetpotato whitefly, Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) is a major pest of economically important crops worldwide. Both the United Kingdom (UK) and Finland hold Protected Zone status against this invasive pest. As a result B. tabaci entering these countries on plants and plant produce is subjected to a policy of eradication. The impact of B. tabaci entering, and becoming established, is that it is an effective vector of many plant viruses that are not currently found in the protected zones. The Mediterranean species is the most commonly intercepted species of B. tabaci entering both the UK and Finland. The implications of maintaining Protected Zone status are discussed. PMID:26463194

  15. Dietary Quality Maintained among Overweight Brazilian Women Enrolled in a Primary Healthcare Service

    OpenAIRE

    Martins Horta, Paula; Souza Lopes, Aline Cristine; dos Santos, Luana Caroline

    2014-01-01

    ABSTRACT The present study aimed to evaluate the dietary quality maintained among 113 overweight [body mass index (BMI) ≥25.0 kg/m2] women aged ≥20 years, who were enrolled in a Brazilian primary healthcare service in 2009. Dietary quality was evaluated using the Healthy Eating Index (HEI)-1995, which was adapted in the Brazilian context. Statistical analysis included linear regression adjusted by self-reporting energy intake. The prevalence of obesity (BMI ≥30.0 kg/m2), elevated waist-circum...

  16. Attaining and maintaining a continuity of knowledge to draw safeguards conclusions with confidence

    International Nuclear Information System (INIS)

    As the 21. century progresses, new nuclear facilities and the expansion of nuclear activities into new countries will require the International Atomic Energy Agency (IAEA) to place a higher reliance on attaining and maintaining a Continuity of Knowledge (CoK) of its safeguards information than is currently practiced. Additionally, a conceptual view of where and how CoK can be applied will need to evolve to support improved efficiency and efficacy of drawing a safeguards conclusion for each Member State. The ability to draw a safeguards conclusion for a Member State will be predicated on the confidence that CoK has been attained and subsequently maintained with respect to the data and information streams used by the IAEA. This confidence can be described as a function of factors such as elapsed time since the measurement, surveillance of attributes, authentication of information, historic knowledge of potential system failures, and the number and type of data collections. A set of general scenarios are described for determining what is required to attain CoK and whether CoK has been maintained. A high‑level analysis of example scenarios is presented to identify failures or gaps that could cause a loss of CoK. Potential areas for technological research and development are discussed for the next generation of CoK tools.

  17. Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program.

    Science.gov (United States)

    Shao, Mengle; Ishibashi, Jeff; Kusminski, Christine M; Wang, Qiong A; Hepler, Chelsea; Vishvanath, Lavanya; MacPherson, Karen A; Spurgin, Stephen B; Sun, Kai; Holland, William L; Seale, Patrick; Gupta, Rana K

    2016-06-14

    The transcriptional regulators Ebf2 and Prdm16 establish and maintain the brown and/or beige fat cell identity. However, the mechanisms operating in white adipocytes to suppress the thermogenic gene program and maintain an energy-storing phenotype are less understood. Here, we report that the transcriptional regulator Zfp423 is critical for maintaining white adipocyte identity through suppression of the thermogenic gene program. Zfp423 expression is enriched in white versus brown adipocytes and suppressed upon cold exposure. Doxycycline-inducible inactivation of Zfp423 in mature adipocytes, combined with β-adrenergic stimulation, triggers a conversion of differentiated adiponectin-expressing inguinal and gonadal adipocytes into beige-like adipocytes; this reprogramming event is sufficient to prevent and reverse diet-induced obesity and insulin resistance. Mechanistically, Zfp423 acts in adipocytes to inhibit the activity of Ebf2 and suppress Prdm16 activation. These data identify Zfp423 as a molecular brake on adipocyte thermogenesis and suggest a therapeutic strategy to unlock the thermogenic potential of white adipocytes in obesity. PMID:27238639

  18. Long-Term Surveillance and Maintenance Records: Maintaining Access to the Knowledge - 13122

    International Nuclear Information System (INIS)

    The U.S. Department of Energy (DOE) Office of Legacy Management (LM) is an integral part of DOE's strategy to ensure that legacy liabilities of former nuclear weapons production sites are properly managed following the completion of environmental cleanup activities. In the area of environmental legacy management, records management is crucial to the protection of health, environmental, and legal interests of the Department and the public. LM is responsible for maintaining long-term surveillance and maintenance (LTS and M) records in performance of its mission. Maintaining access to the knowledge contained in these record collections is one of LM's primary responsibilities. To fulfill this responsibility, LM established a consolidated records management facility, the LM Business Center (LMBC), to house physical media records and electronic records. A new electronic record keeping system (ERKS) was needed to replace an obsolete system while helping to ensure LM is able to meet ongoing responsibilities to maintain access to knowledge and control the life cycle management of records. (authors)

  19. Maintaining BC's hydro endowment for the benefit of consumers

    International Nuclear Information System (INIS)

    This paper outlined the development of electricity market arrangements in British Columbia, as well as options and an approach for endowment. Endowment has been made possible by past provincial investment in hydroelectric facilities on the Peace and Columbia Rivers. The facilities on these rivers have met the electricity needs for BC without adding new generation. The annual value of endowment is estimated at more than $500 million. The challenge is to build and maintain an efficient power sector which keeps the benefits of past decisions while securing appropriate decisions for the future. In the past 2 years, BC has been a net importer and needs new generation and possible transmission capacity, depending on where the new generation will be located. It was emphasized that decisions are needed now in order to avoid shortfalls, particularly with the assumption that the Burrard Thermal power station will be shut down. The development of a wholesale electricity market is key to maintaining the endowment benefit in British Columbia. 3 figs

  20. How to keep punishment to maintain cooperation: Introducing social vaccine

    Science.gov (United States)

    Yamamoto, Hitoshi; Okada, Isamu

    2016-02-01

    Although there is much support for the punishment system as a sophisticated approach to resolving social dilemmas, more than a few researchers have also pointed out the limitations of such an approach. Second-order free riding is a serious issue facing the punishment system. Various pioneering works have suggested that an anti-social behavior or noise stemming from a mutation may, surprisingly, be helpful for avoiding second-order freeloaders. In this work, we show through mathematical analysis and an agent-based simulation of a model extending the meta-norms game that the coercive introduction of a small number of non-cooperators can maintain a cooperative regime robustly. This paradoxical idea was inspired by the effect of a vaccine, which is a weakened pathogen injected into a human body to create antibodies and ward off infection by that pathogen. Our expectation is that the coercive introduction of a few defectors, i.e., a social vaccine, will help maintain a highly cooperative regime because it will ensure that the punishment system works.

  1. Acquiring and maintaining a normal oral microbiome: current perspective

    Directory of Open Access Journals (Sweden)

    Egija eZaura

    2014-06-01

    Full Text Available The oral microbiota survives daily physical and chemical perturbations from the intake of food and personal hygiene measures, resulting in a long-term stable microbiome. Biological properties that confer stability in the microbiome are important for the prevention of dysbiosis – a microbial shift towards a disease, e.g., periodontitis or caries. Although processes that underlie oral diseases have been studied extensively, processes involved in maintaining of a normal, healthy microbiome are poorly understood. In this review we present our hypothesis on how a healthy oral microbiome is acquired and maintained. We introduce our view on the prenatal development of tolerance for the normal oral microbiome: we propose that development of fetal tolerance towards the microbiome of the mother during pregnancy is the major factor for a successful acquisition of a normal microbiome. We describe the processes that influence the establishment of such microbiome, followed by our perspective on the process of sustaining a healthy oral microbiome. We divide microbiome-maintenance factors into host-derived and microbe-derived, while focusing on the host. Finally, we highlight the need and directions for future research.

  2. Trek1 contributes to maintaining nasal epithelial barrier integrity.

    Science.gov (United States)

    Jiang, Jing; Liu, Jiang-Qi; Li, Jing; Li, Meng; Chen, Hong-Bin; Yan, Hao; Mo, Li-Hua; Qiu, Shu-Qi; Liu, Zhi-Gang; Yang, Ping-Chang

    2015-01-01

    Epithelial barrier integrity is critical to maintain the homeostasis in the body. The regulatory mechanism of the epithelial barrier function has not been fully understood. This study aims to elucidate the role of the TWIK-related potassium channel-1 (Trek1) in the regulation of the epithelial barrier function of the nasal mucosa. In this study, the levels of Trek1 were assessed by real time RT-PCR and Western blotting. The epithelial barrier function of the rat nasal epithelia was evaluated by the Ussing chamber system. The results showed that Trek1 was detected in the human and rat nasal epithelia, which were significantly lower in patients and rats with allergic rhinitis than that in healthy controls. Exposure to the signature T helper 2 cytokine, interleukin (IL)-4, markedly suppressed the expression of Trek1 in the nasal mucosa via up regulating the expression of the histone deacetylase (HDAC)1. The IL-4-induced rat nasal epithelial barrier dysfunction could be blocked by HDAC1 inhibitor (Trichostatin A), or sodium butyrate, or administration of Clostridium Butyricum. We conclude that Trek1 is critical to maintain the nasal epithelial barrier function. PMID:25778785

  3. Multiple Relationships : Maintaining Professional Identity in Rural Social Work Practice

    Directory of Open Access Journals (Sweden)

    Keith Brownlee

    2015-03-01

    Full Text Available Working in a rural community locates the professional in a wider social network as community members often expect more from their professionals; not only as service providers, but also as engaged members of the community. This can result in the rural social worker being highly visible both personally and professionally and it can also lead to overlapping relationships. These higher expectations can place stress on the worker in terms of maintaining accepted professional roles and a sense of professional identity. This qualitative study explores the first-hand experiences of a cross-section of service providers in more than a dozen communities within northwestern Ontario and northern Manitoba, Canada. The responses of the participants provide some insight into how rural practitioners maintain their professional identity when working within the unique demands of the rural and remote context. Recurring themes from the interviews suggest that these professionals craft their own informal decision-making processes to address intersecting roles, community gossip, and personal isolation, even while, in some cases, practicing in their home community. The findings provide greater understanding of the pressures and realities of working in small remote towns and the challenges of responding to the expectations and realities of relationships including the expectation of working with friends and family members of friends or colleagues: issues that have not been adequately studied in the literature to date.

  4. Extending Access Management to maintain audit logs in cloud computing

    Directory of Open Access Journals (Sweden)

    Ajay Prasad

    2014-01-01

    Full Text Available Considering the most often talked about security risks in cloud computing, like, security and compliance, viability, lack of transparency, reliability and performance issues. Bringing strong auditability in cloud services can reduce these risks to a great extent. Also, auditing, both internally and externally is generally required and sometimes unavoidable looking into the present day competition in the business arena. Auditing in web based and cloud based usage environments focuses mainly on cost of a service which determines the overall expenditure of the user organization. However, the expenditure can be controlled by a collaborative approach between the provider company and the user organization by constantly monitoring the end user access and usage of subscribed cloud services. Though, many cloud providers will claim of having a robust auditable feature, the generic verifiability with sustainable long term recording of usage logs do not exist at all. Certain access management models can be perfectly extended to maintain audit logs for long terms. However, maintaining long term logs certainly has storage implications, especially with larger organizations. The storage implications need to be studied.

  5. Towards possibility of self-maintained vacuum traversible wormhole

    OpenAIRE

    Khatsymovsky, V.

    1996-01-01

    We calculate renormalised vacuum expectation values of electromagnetic stress-energy tensor in the static spherically-symmetrical wormhole topology. We find that for metric tensor sufficiently slow varied with distance violation of the averaged weak energy condition takes place irrespectively of the detailed form of metric. This is a necessary condition for the electromagnetic vacuum to be able to support the wormhole geometry.

  6. Ecuador to withdraw from OPEC; group to maintain present flow

    International Nuclear Information System (INIS)

    This paper reports that the Organization of Petroleum Exporting Countries, which has agreed to maintain its present combined production of 24.2 million b/d of oil in the fourth quarter, will soon see the first pullout of a member. The 13 member group will shrink to 12, probably in November, when Ecuador withdraws. Ecuador President Sixto Duran Ballen issued notice of the pullout Sept. 17, a little more than 1 month after he took office. Ecuador, strapped for cash, wants to save OPEC membership dues reported to be $2-3 million/year. It plans to remain an associate member, although it wasn't immediately clear what that means. No other countries are regarded as associate members

  7. Can we maintain our advanced expertise in nuclear technology?

    International Nuclear Information System (INIS)

    The paper explains why it is important in the light of the Federal Government's plans to wind down nuclear power generation, to provide for governmental or other programmes for ensuring that the advanced expertise in nuclear science and technology in Germany will be maintained well into the future and passed on to the next generation of scientists and (radiation protection) engineers, as a policy to accompany the present Government's plans for a national nuclear power phaseout. The necessity for hedging Germany's high standards and the know-how in nuclear science and technology is explained, not least with respect to protection of the population from the hazards emanating from the operation of nuclear facilities. (orig./CB)

  8. Rewarding peer reviewers: maintaining the integrity of science communication.

    Science.gov (United States)

    Gasparyan, Armen Yuri; Gerasimov, Alexey N; Voronov, Alexander A; Kitas, George D

    2015-04-01

    This article overviews currently available options for rewarding peer reviewers. Rewards and incentives may help maintain the quality and integrity of scholarly publications. Publishers around the world implemented a variety of financial and nonfinancial mechanisms for incentivizing their best reviewers. None of these is proved effective on its own. A strategy of combined rewards and credits for the reviewers1 creative contributions seems a workable solution. Opening access to reviews and assigning publication credits to the best reviews is one of the latest achievements of digitization. Reviews, posted on academic networking platforms, such as Publons, add to the transparency of the whole system of peer review. Reviewer credits, properly counted and displayed on individual digital profiles, help distinguish the best contributors, invite them to review and offer responsible editorial posts. PMID:25829801

  9. Methods of achieving and maintaining an appropriate caesarean section rate.

    LENUS (Irish Health Repository)

    Robson, Michael

    2013-04-01

    Caesarean section rates continue to increase worldwide. The appropriate caesarean section rate remains a topic of debate among women and professionals. Evidence-based medicine has not provided an answer and depends on interpretation of the literature. Overall caesarean section rates are unhelpful, and caesarean section rates should not be judged in isolation from other outcomes and epidemiological characteristics. Better understanding of caesarean section rates, their consequences and their benefits will improve care, and enable learning between delivery units nationally and internationally. To achieve and maintain an appropriate caesarean section rate requires a Multidisciplinary Quality Assurance Programme in each delivery unit, recognising caesarean section rates as one of many factors that determine quality. Women will always choose the type of delivery that seems safest to them and their babies. Professionals need to monitor the quality of their practice continuously in a standardised way to ensure that women can make the right choice.

  10. Maintaining Atmospheric Mass and Water Balance Within Reanalysis

    Science.gov (United States)

    Takacs, Lawrence L.; Suarez, Max; Todling, Ricardo

    2015-01-01

    This report describes the modifications implemented into the Goddard Earth Observing System Version-5 (GEOS-5) Atmospheric Data Assimilation System (ADAS) to maintain global conservation of dry atmospheric mass as well as to preserve the model balance of globally integrated precipitation and surface evaporation during reanalysis. Section 1 begins with a review of these global quantities from four current reanalysis efforts. Section 2 introduces the modifications necessary to preserve these constraints within the atmospheric general circulation model (AGCM), the Gridpoint Statistical Interpolation (GSI) analysis procedure, and the Incremental Analysis Update (IAU) algorithm. Section 3 presents experiments quantifying the impact of the new procedure. Section 4 shows preliminary results from its use within the GMAO MERRA-2 Reanalysis project. Section 5 concludes with a summary.

  11. JWIG: Yet Another Framework for Maintainable and Secure Web Applications

    DEFF Research Database (Denmark)

    Møller, Anders; Schwarz, Mathias Romme

    2009-01-01

    Although numerous frameworks for web application programming have been developed in recent years, writing web applications remains a challenging task. Guided by a collection of classical design principles, we propose yet another framework. It is based on a simple but flexible server-oriented arch...... services.The resulting framework provides a novel foundation for developing maintainable and secure web applications.......Although numerous frameworks for web application programming have been developed in recent years, writing web applications remains a challenging task. Guided by a collection of classical design principles, we propose yet another framework. It is based on a simple but flexible server......-oriented architecture that coherently supports general aspects of modern web applications, including dynamic XML construction, session management, data persistence, caching, and authentication, but it also simplifies programming of server-push communication and integration of XHTML-based applications and XML-based web...

  12. Creating and maintaining chemical artificial life by robotic symbiosis

    DEFF Research Database (Denmark)

    Hanczyc, Martin M.; Parrilla, Juan M.; Nicholson, Arwen;

    2015-01-01

    We present a robotic platform based on the open source RepRap 3D printer that can print and maintain chemical artificial life in the form of a dynamic, chemical droplet. The robot uses computer vision, a self-organizing map, and a learning program to automatically categorize the behavior...... of the droplet that it creates. The robot can then use this categorization to autonomously detect the current state of the droplet and respond. The robot is programmed to visually track the droplet and either inject more chemical fuel to sustain a motile state or introduce a new chemical component that results...... confluence of chemical, artificial intelligence, and robotic approaches to artificial life....

  13. The effects of irradiation on Babesia maintained in vitro

    International Nuclear Information System (INIS)

    Blood infected with Babesia rodhaini, B major or B divergens was irradiated to different absorbed doses between 0 and 120 krad, and then maintained in vitro in the presence of 3H hypoxanthine for 24 h. The effects of irradiation were measured by the ability of the parasites to incorporate 3H hypoxanthine and, in the case of B rodhaini, by the ability of the parasite to infect mice. B major and B divergens were slightly more radioresistant than B rodhaini, but all showed a progressive fall in ability to incorporate 3H hypoxanthine with increasing does of irradiation when there was increased uptake of 3H hypoxanthine. In the case of B rodhaini there was close correlation between the ability of the parasites to incorporate 3H hypoxanthine and their infectivity for mice. Both types of activity were abolished at doses of 40 krad and above. (author)

  14. Reliability and Maintainability Data for Liquid Metal Cooling Systems

    Energy Technology Data Exchange (ETDEWEB)

    Cadwallader, Lee Charles [Idaho National Laboratory

    2015-05-01

    One of the coolants of interest for future fusion breeding blankets is lead-lithium. As a liquid metal it offers the advantages of high temperature operation for good station efficiency, low pressure, and moderate flow rate. This coolant is also under examination for use in test blanket modules to be used in the ITER international project. To perform reliability, availability, maintainability and inspectability (RAMI) assessment as well as probabilistic safety assessment (PSA) of lead-lithium cooling systems, component failure rate data are needed to quantify the system models. RAMI assessment also requires repair time data and inspection time data. This paper presents a new survey of the data sets that are available at present to support RAMI and PSA quantification. Recommendations are given for the best data values to use when quantifying system models.

  15. Exploring the Potential of Creatine Ingestion to Maintain Muscle Function during Immobilization

    Directory of Open Access Journals (Sweden)

    Jeremy C. Fransen

    2015-08-01

    Full Text Available Limb immobilization (casting results in a loss of muscle mass along with decrements in muscle strength and endurance. In addition, immobilization has been shown to impair high energy phosphate catabolism in skeletal muscle. Creatine ingestion in conjunction with resistance training can significantly increase muscle force production, augment muscle size increases, and improve energy-rich phosphate catabolism in skeletal muscle. Surprisingly, there are few research studies investigating the potential of oral creatine supplementation to mitigate the muscle changes during immobilization. Early investigations found that creatine supplementation can maintain muscle size, strength, and endurance during short-term (1-2 wk immobilization. Future research should focus on whether creatine supplementation can also prevent muscle metabolic consequences during immobilization. Creatine ingestion during short-term immobilization may help to identify the underlying mechanisms that contribute to the reported ergogenic effects.

  16. Distributed Amplify and Forward Cooperation While Maintaining Transmission Freedom

    Directory of Open Access Journals (Sweden)

    L. Chen

    2011-01-01

    Full Text Available Problem statement: This study proposes a novel Distributed Amplify and-Forward (DAF cooperative scheme, achieving higher diver¬sity order and yet maintaining the same transmission freedom as the conventional Amplify-and-Forward (AF scheme. In the DAF scheme, a user’s transmitted symbols are partitioned into several sequences in order to be relayed by different users. Approach: In the cooperative network, each user still uses half of their transmission for relaying others’ signals. But instead of relaying one user’s entire transmitted sequence, it helps different users for the relaying. Theoretical analysis of the DAF scheme is carried out in order to justify its advantages over the existing schemes. The outage behavior and Diversity-Multiplexing Tradeoff (DMT analyses of the DAF scheme are presented. Results: Through outage behavior analysis, it is shown the DAF scheme achieves substantial diversity gains over the AF scheme. Furthermore, the DMT analysis justices both the scheme’s achievable diversity gains and its ability to maintain the same multiplexing gain as the AF scheme. The theoretical analyses are then extended to a general cooperative network consisting of N (N≥2 relays, showing the diversity order can be increased with respect to the number of relays but not at the expense of each user’s multiplexing gain. Conclusion: Finally, a practical coded cooperative system that integrates the DAF scheme with the concatenated Reed-Solomon Convolution Codes (RSCC is proposed, validating the achievable performance gain offered by the DAF scheme.

  17. Human sclera maintains common characteristics with cartilage throughout evolution.

    Directory of Open Access Journals (Sweden)

    Yuko Seko

    Full Text Available BACKGROUND: The sclera maintains and protects the eye ball, which receives visual inputs. Although the sclera does not contribute significantly to visual perception, scleral diseases such as refractory scleritis, scleral perforation and pathological myopia are considered incurable or difficult to cure. The aim of this study is to identify characteristics of the human sclera as one of the connective tissues derived from the neural crest and mesoderm. METHODOLOGY/PRINCIPAL FINDINGS: We have demonstrated microarray data of cultured human infant scleral cells. Hierarchical clustering was performed to group scleral cells and other mesenchymal cells into subcategories. Hierarchical clustering analysis showed similarity between scleral cells and auricular cartilage-derived cells. Cultured micromasses of scleral cells exposed to TGF-betas and BMP2 produced an abundant matrix. The expression of cartilage-associated genes, such as Indian hedge hog, type X collagen, and MMP13, was up-regulated within 3 weeks in vitro. These results suggest that human 'sclera'-derived cells can be considered chondrocytes when cultured ex vivo. CONCLUSIONS/SIGNIFICANCE: Our present study shows a chondrogenic potential of human sclera. Interestingly, the sclera of certain vertebrates, such as birds and fish, is composed of hyaline cartilage. Although the human sclera is not a cartilaginous tissue, the human sclera maintains chondrogenic potential throughout evolution. In addition, our findings directly explain an enigma that the sclera and the joint cartilage are common targets of inflammatory cells in rheumatic arthritis. The present global gene expression database will contribute to the clarification of the pathogenesis of developmental diseases such as high myopia.

  18. Cost-effective solutions to maintaining smart grid reliability

    Science.gov (United States)

    Qin, Qiu

    As the aging power systems are increasingly working closer to the capacity and thermal limits, maintaining an sufficient reliability has been of great concern to the government agency, utility companies and users. This dissertation focuses on improving the reliability of transmission and distribution systems. Based on the wide area measurements, multiple model algorithms are developed to diagnose transmission line three-phase short to ground faults in the presence of protection misoperations. The multiple model algorithms utilize the electric network dynamics to provide prompt and reliable diagnosis outcomes. Computational complexity of the diagnosis algorithm is reduced by using a two-step heuristic. The multiple model algorithm is incorporated into a hybrid simulation framework, which consist of both continuous state simulation and discrete event simulation, to study the operation of transmission systems. With hybrid simulation, line switching strategy for enhancing the tolerance to protection misoperations is studied based on the concept of security index, which involves the faulted mode probability and stability coverage. Local measurements are used to track the generator state and faulty mode probabilities are calculated in the multiple model algorithms. FACTS devices are considered as controllers for the transmission system. The placement of FACTS devices into power systems is investigated with a criterion of maintaining a prescribed level of control reconfigurability. Control reconfigurability measures the small signal combined controllability and observability of a power system with an additional requirement on fault tolerance. For the distribution systems, a hierarchical framework, including a high level recloser allocation scheme and a low level recloser placement scheme, is presented. The impacts of recloser placement on the reliability indices is analyzed. Evaluation of reliability indices in the placement process is carried out via discrete event

  19. Promoting a learning culture to maintain the nuclear safety competence of AECB staff

    International Nuclear Information System (INIS)

    In the Canadian regulatory approach, the safe operation of a nuclear installation is primarily the responsibility of the operator. The mission of the Atomic Energy Control Board (AECB) is to ensure that the use of nuclear energy does not pose unnecessary risk to workers, the general public and the environment. The AECB fulfills this responsibility through a comprehensive licensing framework in which compliance with regulatory standards and requirements is assured through systematic safety assessments, inspection and enforcement. These responsibilities require regulatory staff with specialized academic backgrounds and work experience related to the industry. In the past, the AECB readily attracted and retained the qualified personnel needed to ensure nuclear safety competence. However, several factors are now altering this situation. Anticipated retirement in the years ahead among the current generation of staff will result in significant losses of corporate knowledge and experience. In addition, the stagnation of the domestic nuclear power industry has impacted significantly on the recruitment of suitably qualified replacement candidates. Many Canadian universities have had to reduce their nuclear programmes as fewer undergraduate and postgraduate students choose a nuclear career option. In these circumstances, maintaining the AECB's nuclear safety competence requires a more systematic and deliberate approach. This paper describes the measures that the AECB has taken and is planning to take to promote a learning environment, and to assist staff in establishing and maintaining their knowledge and skills. (author)

  20. Recommended techniques for effective maintainability. A continuous improvement initiative of the NASA Reliability and Maintainability Steering Committee

    Science.gov (United States)

    1994-01-01

    This manual presents a series of recommended techniques that can increase overall operational effectiveness of both flight and ground based NASA systems. It provides a set of tools that minimizes risk associated with: (1) restoring failed functions (both ground and flight based); (2) conducting complex and highly visible maintenance operations; and (3) sustaining a technical capability to support the NASA mission using aging equipment or facilities. It considers (1) program management - key elements of an effective maintainability effort; (2) design and development - techniques that have benefited previous programs; (3) analysis and test - quantitative and qualitative analysis processes and testing techniques; and (4) operations and operational design techniques that address NASA field experience. This document is a valuable resource for continuous improvement ideas in executing the systems development process in accordance with the NASA 'better, faster, smaller, and cheaper' goal without compromising safety.

  1. Issues and Methods for Assessing COTS Reliability, Maintainability, and Availability

    Science.gov (United States)

    Schneidewind, Norman F.; Nikora, Allen P.

    1998-01-01

    Many vendors produce products that are not domain specific (e.g., network server) and have limited functionality (e.g., mobile phone). In contrast, many customers of COTS develop systems that am domain specific (e.g., target tracking system) and have great variability in functionality (e.g., corporate information system). This discussion takes the viewpoint of how the customer can ensure the quality of COTS components. In evaluating the benefits and costs of using COTS, we must consider the environment in which COTS will operate. Thus we must distinguish between using a non-mission critical application like a spreadsheet program to produce a budget and a mission critical application like military strategic and tactical operations. Whereas customers will tolerate an occasional bug in the former, zero tolerance is the rule in the latter. We emphasize the latter because this is the arena where there are major unresolved problems in the application of COTS. Furthermore, COTS components may be embedded in the larger customer system. We refer to these as embedded systems. These components must be reliable, maintainable, and available, and must be with the larger system in order for the customer to benefit from the advertised advantages of lower development and maintenance costs. Interestingly, when the claims of COTS advantages are closely examined, one finds that to a great extent these COTS components consist of hardware and office products, not mission critical software [1]. Obviously, COTS components are different from custom components with respect to one or more of the following attributes: source, development paradigm, safety, reliability, maintainability, availability, security, and other attributes. However, the important question is whether they should be treated differently when deciding to deploy them for operational use; we suggest the answer is no. We use reliability as an example to justify our answer. In order to demonstrate its reliability, a COTS

  2. Energies

    International Nuclear Information System (INIS)

    This special dossier 'energies' is made of 6 contributions dealing with: the EPR, the European Pressurized Reactor (Bertrand Barre); nuclear weapons proliferation, the real threat (Bernard Lerouge); Proliferation in a globalizing economy (Georges Le Guelte); the compared efficiency of US and Electricite de France's nuclear parks in exploitation (Laurent Stricker, Jacques Leclercq); Why financing and how to finance the security of power supply (Fabien Chone); thoughts on the calls for competition of electricity production (Jacques Clade)

  3. Maintaining genetic integrity in aging: a zero sum game.

    Science.gov (United States)

    Suh, Yousin; Vijg, Jan

    2006-01-01

    Aging of somatic cells can be defined as the gradual loss of the information embedded in the global and local properties of complex macromolecular networks. This loss of information may reflect the dynamic interplay between stochastic factors, such as the accumulation of unrepaired somatic damage, and gene-encoded programmatic responses. This would ultimately result in loss of function, impaired response to environmental challenge, and a progressively increased incidence of disease. Here the authors present the case for aging as a continuous battle between maintaining genomic integrity and ensuring sufficient cell functional mass. Focusing on aging of the liver in rodents, evidence is presented that normal aging is associated with a gradual accumulation of random alterations in the DNA of the genome as a consequence of imperfect DNA repair and a decrease in the rate of DNA damage-induced apoptosis. Apoptosis is the cell's genome maintenance mechanism of last resort and an imbalance towards apoptosis can contribute to manifestations of aging-related phenotypes, as exemplified by mouse models of premature aging due to genetic defects in genome maintenance. Prospects to reset the clock in this zero sum game between survival and the maintenance of phenotypic integrity will be discussed. PMID:16677100

  4. Arsenite maintains germinative state in cultured human epidermal cells

    International Nuclear Information System (INIS)

    Arsenic is a well-known carcinogen for human skin, but its mechanism of action and proximal macromolecular targets remain to be elucidated. In the present study, low micromolar concentrations of sodium arsenite maintained the proliferative potential of epidermal keratinocytes, decreasing their exit from the germinative compartment under conditions that promote differentiation of untreated cells. This effect was observed in suspension and in post-confluent surface cultures as measured by colony-forming ability and by proportion of rapidly adhering colony-forming cells. Arsenite-treated cultures exhibited elevated levels of β1-integrin and β-catenin, two proteins enriched in cells with high proliferative potential. Levels of phosphorylated (inactive) glycogen synthase kinase 3β were higher in the treated cultures, likely accounting for the increased levels of transcriptionally available β-catenin. These findings suggest that arsenic could have co-carcinogenic and tumor co-promoting activities in the epidermis as a result of increasing the population and persistence of germinative cells targeted by tumor initiators and promoters. These findings also identify a critical signal transduction pathway meriting further exploration in pursuit of this phenomenon

  5. Reliability and maintainability analysis of electrical system of drum shearers

    Institute of Scientific and Technical Information of China (English)

    SEYED Hadi Hoseinie; MOHAMMAD Ataei; REZA Khalokakaie; UDAY Kumar

    2011-01-01

    The reliability and maintainability of electrical system of drum shearer at Parvade.l Coal Mine in central Iran was analyzed. The maintenance and failure data were collected during 19 months of shearer operation. According to trend and serial correlation tests, the data were independent and identically distributed (iid) and therefore the statistical techniques were used for modeling. The data analysis show that the time between failures (TBF) and time to repair (TTR) data obey the lognormal and Weibull 3 parameters distribution respectively. Reliability-based preventive maintenance time intervals for electrical system of the drum shearer were calculated with regard to reliability plot. The reliability-based maintenance intervals for 90%, 80%, 70% and 50% reliability level are respectively 9.91, 17.96, 27.56 and 56.1 h. Also the calculations show that time to repair (TTR) of this system varies in range 0.17-4 h with 1.002 h as mean time to repair (MTTR). There is a 80% chance that the electrical system of shearer of Parvade.l mine repair will be accomplished within 1.45 h.

  6. Web-Based Environment for Maintaining Legacy Software

    Science.gov (United States)

    Tigges, Michael; Thompson, Nelson; Orr, Mark; Fox, Richard

    2007-01-01

    Advanced Tool Integration Environment (ATIE) is the name of both a software system and a Web-based environment created by the system for maintaining an archive of legacy software and expertise involved in developing the legacy software. ATIE can also be used in modifying legacy software and developing new software. The information that can be encapsulated in ATIE includes experts documentation, input and output data of tests cases, source code, and compilation scripts. All of this information is available within a common environment and retained in a database for ease of access and recovery by use of powerful search engines. ATIE also accommodates the embedment of supporting software that users require for their work, and even enables access to supporting commercial-off-the-shelf (COTS) software within the flow of the experts work. The flow of work can be captured by saving the sequence of computer programs that the expert uses. A user gains access to ATIE via a Web browser. A modern Web-based graphical user interface promotes efficiency in the retrieval, execution, and modification of legacy code. Thus, ATIE saves time and money in the support of new and pre-existing programs.

  7. Maintaining maximum valid data recovery from a meteorological monitoring system

    International Nuclear Information System (INIS)

    Meteorological monitoring at a nuclear plant is mandatory and must satisfy specific US Nuclear Regulatory Commission requirements. Meteorological monitoring requirements have changed dramatically since the Three Mile Island Nuclear Plant accident, and it has become an integral part of nuclear emergency preparedness. The manner in which a meteorological monitoring network at the Indian Point Nuclear Power Plant is being maintained assures a maximum value of valid data recovery for all meteorological parameters. Only data that are reliable and valid can be used for making the proper decisions for safety in the event of an on-site plant emergency. The local weather conditions must be known at all times in the event of a radioactive release, so that plume dispersion can be satisfactorily evaluated and protective action recommendations can be taken. It an evacuation is deemed necessary, this evacuation must take place in the proper direction to fully protect the general public. By following the guidelines developed for use at the Indian Point Nuclear Power Plants valid data recovery well in excess of 95% has been achieved during the plants 15 yr of operation

  8. Customer retention: maintaining the competitive edge in the retail market

    Energy Technology Data Exchange (ETDEWEB)

    Wright, T. [CitiPower Ltd., Melbourne, VIC (Australia)

    1997-09-01

    The current market environment in the electricity industry is one of changing regulations with many of the rules being developed. There is a great deal of customer confusion and uncertainty with some customers unaware of their contestable status and many are insecure about mixing retail and distribution supplies. This paper discusses customer retention and maintaining the competitive edge in the retail market. It draws on some conclusions from a survey released by the Australian Chamber of Manufacturers entitled `Customer feedback on Victoria`s competitive electricity market`. An overview is presented of the retail market in Australia which is one of very strong price-based competition, with as yet little differentiation. A process is described for retaining customers which involves asking the customer what he/she wants in a language which they understand. The best way to determine customer needs is through a combination of internal and external sources. Enhancing customer loyalty and differentiating and marketing the product are also discussed. As the market matures, customer retention and satisfaction will be based on value added services at a reasonable cost. (author). 6 figs.

  9. Mosquito C-type lectins maintain gut microbiome homeostasis.

    Science.gov (United States)

    Pang, Xiaojing; Xiao, Xiaoping; Liu, Yang; Zhang, Rudian; Liu, Jianying; Liu, Qiyong; Wang, Penghua; Cheng, Gong

    2016-01-01

    The long-term evolutionary interaction between the host immune system and symbiotic bacteria determines their cooperative rather than antagonistic relationship. It is known that commensal bacteria have evolved a number of mechanisms to manipulate the mammalian host immune system and maintain homeostasis. However, the strategies employed by the microbiome to overcome host immune responses in invertebrates still remain to be understood. Here, we report that the gut microbiome in mosquitoes utilizes C-type lectins (mosGCTLs) to evade the bactericidal capacity of antimicrobial peptides (AMPs). Aedes aegypti mosGCTLs facilitate colonization by multiple bacterial strains. Furthermore, maintenance of the gut microbial flora relies on the expression of mosGCTLs in A. aegypti. Silencing the orthologues of mosGCTL in another major mosquito vector (Culex pipiens pallens) also impairs the survival of gut commensal bacteria. The gut microbiome stimulates the expression of mosGCTLs, which coat the bacterial surface and counteract AMP activity. Our study describes a mechanism by which the insect symbiotic microbiome offsets gut immunity to achieve homeostasis. PMID:27572642

  10. A Cdc2 dependent checkpoint maintains diploidy in Drosophila.

    Science.gov (United States)

    Hayashi, S

    1996-04-01

    DNA replication in G2 does not normally occur due to the checkpoint control. To elucidate its mechanism, the functions of the escargot and Dmcdc2 genes of Drosophila were studied. When escargot function was eliminated, diploid imaginal cells that were arrested in G2 lost Cyclin A, a regulatory subunit of G2/M cdk, and entered an endocycle. escargot genetically interacted with Dmcdc2 which encodes a catalytic subunit of G2/M cdk. The mutant phenotypes of Dmcdc2 itself was similar to those of escargot: many diploid cells in imaginal discs, salivary glands and the central nervous system entered an endocycle and sometimes formed polytene chromosomes. Since mitotically quiescent abdominal histoblasts still required Dmcdc2 to remain diploid, the inhibitory activity of G2/M cdk on DNA replication appeared to be separable from its activity as the mitosis promoting factor. These results suggest that in G2, escargot is required to maintain a high level of G2/M cdk that actively inhibits the entry into S phase. PMID:8620832

  11. Polarization-maintaining amplifier based on 3C fiber structures

    Science.gov (United States)

    Enokidani, Jun; Ito, Rumi; Sakurai, Tsutomu; Shin, Sumida; Tei, Kazuyoku

    2015-03-01

    Chirally-Coupled-Core (3C) fiber structure can preserve a single mode quality and even a linear polarization for a large core size. A principal advantage of fiber laser is its compatibility with monolithic integration and robust system. But so far, devices such as a combiner using the 3C fibers have not been reported. Here we report the first demonstration of such monolithic amplifier structure which contains an active fiber and a combiner based on 3C fibers. A single-stage amplifier is seeded by an EO Q-switched micro-laser and pumped by two high power fiber pigtailed 976-nm laser diodes via an in-house fabricated (2 + 1) × 1 pump signal combiner. The active fiber is based on a 3-m-long, 3C Yb-doped fiber (33 μm/250 μm core/cladding diameter with 0.06/0.46 NA). The amplifier demonstrates scaling up to 30W average power and 150 kW peak power in 0.3mJ, 2ns pulses. The beam profiles and beam qualities were characterized as its output power was varied up to 30W. The beam profile was maintained at a high beam quality of around M2=1.2. The spectral properties of the 3C fiber were also characterized as its output peak power was varied.

  12. Specifying colour and maintaining colour accuracy for 3D printing

    Science.gov (United States)

    Parraman, Carinna; Walters, Peter; Reid, Brendan; Huson, David

    2008-02-01

    Advances in rapid prototyping technologies have led to the emergence of three-dimensional printers which can fabricate physical artefacts, including the application of surface colours. In light of these developments, this paper asserts that the need to print colour accurately is just as important for designers using three-dimensional colour printing as it is for two-dimensional inkjet printing. Parallels can be made with two-dimensional digital Inkjet printing and 2D common problems include: on screen previsualisation, colour management methods, colour gamut and maintaining colour accuracy. However, for three dimensional colour printed objects, there are more variables that will affect the finished colour. These are: the powder and process inks, unevenness of the surface, wax post-processing and other infiltration media and procedures. Furthermore, in some 3D printers, the K channel is replaced by the binder and so the printer is only using the cyan, magenta and yellow channels. The paper will suggest methods for improving pre-visualisation and accurate pre-viewing of the colours through the manufacture of three-dimensional colour charts as a reference guide for designers so that they can make accurate coloured artefacts. A series of case studies will be demonstrated.

  13. Biologic Data of Cynomolgus Monkeys Maintained under Laboratory Conditions

    Science.gov (United States)

    Rosso, Marilena Caterina; Badino, Paola; Ferrero, Giulio; Costa, Roberto; Cordero, Francesca; Steidler, Stephanie

    2016-01-01

    The cynomolgus monkey (Macaca fascicularis) is a well-known non-human primate species commonly used in non-clinical research. It is important to know basal clinical pathology parameters in order to have a reference for evaluating any potential treatment-induced effects, maintaining health status among animals and, if needed, evaluating correct substantiative therapies. In this study, data from 238 untreated cynomolgus monkeys (119 males and 119 females of juvenile age, 2.5 to 3.5 years) kept under laboratory conditions were used to build up a reference database of clinical pathology parameters. Twenty-two hematology markers, 24 clinical chemistry markers and two blood coagulation parameters were analyzed. Gender-related differences were evaluated using statistical analyses. To assess the possible effects of stress induced by housing or handling involved in treatment procedures, 78 animals (35 males and 35 females out of 238 juvenile monkeys and four adult males and four adult females) were used to evaluate cortisol, corticosterone and behavioral assessment over time. Data were analyzed using a non-parametric statistical test and machine learning approaches. Reference clinical pathology data obtained from untreated animals may be extremely useful for investigators employing cynomolgus monkeys as a test system for non-clinical safety studies. PMID:27280447

  14. Tractor Mechanics. Maintaining and Servicing the Power Train, Learning Activity Packages 49-53; Maintaining and Servicing the Clutch, Learning Activity Packages 54-59; Maintaining and Servicing the Transmission and Differential, Learning Activity Packages 60-68; Maintaining and Servicing the Final Drive, Learning Activity Packages 69-77.

    Science.gov (United States)

    Clemson Univ., SC. Vocational Education Media Center.

    This series of learning activity packages focuses on four areas of tractor mechanics: (1) maintaining and servicing the power train, (2) maintaining and servicing the clutch, (3) maintaining and servicing the transmission and differential, and (4) maintaining and servicing the final drive. Each of the twenty-nine illustrated learning activity…

  15. Maintaining Your Health & Physical Fitness: Expert Recommendations | Smokefree.gov

    Science.gov (United States)

    The evidence is clear—physical activity helps to reduce the risk of heart disease, diabetes, and cancer. But did you know that it also has many other benefits that support your overall well-being? Other benefits include more positive mood, increased energy, better sleep, and improved stress management. So how much physical activity do we need?

  16. Identifying opportunities to reduce excess nitrogen in croplands while maintaining current crop yields

    Science.gov (United States)

    West, P. C.; Mueller, N. D.; Foley, J. A.

    2011-12-01

    Use of synthetic nitrogen fertilizer has greatly contributed to the increased crop yields brought about by the Green Revolution. Unfortunately, it also has also contributed to substantial excess nitrogen in the environment. Application of excess nitrogen not only is a waste of energy and other resources used to produce, transport and apply it, it also pollutes aquatic ecosystems and has led to the development of more than 200 hypoxic-or "dead"-zones in coastal areas around the world. How can we decrease use of excess nitrogen without compromising crop yields? To help address this challenge, our study (1) quantified hot spots of excess nitrogen, and (2) estimated how much nitrogen reduction is possible in these areas while still maintaining yields. We estimated excess nitrogen for major crops using a mass balance approach and global spatial data sets of crop area and yield, fertilizer application rates, and nitrogen deposition. Hot spots of excess nitrogen were identified by quantifying the smallest area within large river basins that contributed 25% and 50% of the total load within each basin. Nitrogen reduction scenarios were developed using a yield response model to estimate nitrogen application rates needed to maintain current yields. Our research indicated that excess nitrogen is concentrated in very small portions of croplands within river basins, with 25% of the total nitrogen load in each basin from ~10% of the cropland, and 50% of the total nitrogen load in each basin from ~25% of the cropland. Targeting reductions in application rates in these hot spots can allow us to maintain current crop yields while greatly reducing nitrogen loading to coastal areas and creating the opportunity to reallocate resources to boost yields on nitrogen-limited croplands elsewhere.

  17. Mitochondrial membrane potential in human neutrophils is maintained by complex III activity in the absence of supercomplex organisation.

    Directory of Open Access Journals (Sweden)

    Bram J van Raam

    Full Text Available BACKGROUND: Neutrophils depend mainly on glycolysis for their energy provision. Their mitochondria maintain a membrane potential (Deltapsi(m, which is usually generated by the respiratory chain complexes. We investigated the source of Deltapsi(m in neutrophils, as compared to peripheral blood mononuclear leukocytes and HL-60 cells, and whether neutrophils can still utilise this Deltapsi(m for the generation of ATP. METHODS AND PRINCIPAL FINDINGS: Individual activity of the oxidative phosphorylation complexes was significantly reduced in neutrophils, except for complex II and V, but Deltapsi(m was still decreased by inhibition of complex III, confirming the role of the respiratory chain in maintaining Deltapsi(m. Complex V did not maintain Deltapsi(m by consumption of ATP, as has previously been suggested for eosinophils. We show that complex III in neutrophil mitochondria can receive electrons from glycolysis via the glycerol-3-phosphate shuttle. Furthermore, respiratory supercomplexes, which contribute to efficient coupling of the respiratory chain to ATP synthesis, were lacking in neutrophil mitochondria. When HL-60 cells were differentiated to neutrophil-like cells, they lost mitochondrial supercomplex organisation while gaining increased aerobic glycolysis, just like neutrophils. CONCLUSIONS: We show that neutrophils can maintain Deltapsi(m via the glycerol-3-phosphate shuttle, whereby their mitochondria play an important role in the regulation of aerobic glycolysis, rather than producing energy themselves. This peculiar mitochondrial phenotype is acquired during differentiation from myeloid precursors.

  18. Intermittent hypoxia maintains glycemia in streptozotocin-induced diabetic rats.

    Science.gov (United States)

    Chen, Xiaofei; Zhao, Tong; Huang, Xin; Wu, Liying; Wu, Kuiwu; Fan, Ming; Zhu, Lingling

    2016-05-01

    Increasing studies have shown protective effects of intermittent hypoxia on brain injury and heart ischemia. However, the effect of intermittent hypoxia on blood glucose metabolism, especially in diabetic conditions, is rarely observed. The aim of this study was to investigate whether intermittent hypoxia influences blood glucose metabolism in type 1 diabetic rats. Streptozotocin-induced diabetic adult rats and age-matched control rats were treated with intermittent hypoxia (at an altitude of 3 km, 4 h per day for 3 weeks) or normoxia as control. Fasting blood glucose, body weight, plasma fructosamine, plasma insulin, homeostasis model assessment of insulin resistance (HOMA-IR), pancreas β-cell mass, and hepatic and soleus glycogen were measured. Compared with diabetic rats before treatment, the level of fasting blood glucose in diabetic rats after normoxic treatment was increased (19.88 ± 5.69 mmol/L vs. 14.79 ± 5.84 mmol/L, p  0.05). Meanwhile, fasting blood glucose in diabetic rats after hypoxic treatment was also lower than that in diabetic rats after normoxic treatment (13.14 ± 5.77 mmol/L vs. 19.88 ± 5.69 mmol/L, pintermittent hypoxia was significantly lower than that in diabetic rats receiving normoxia (1.28 ± 0.11 vs. 1.39 ± 0.11, p intermittent hypoxia showed effect on the increase of soleus glycogen but not hepatic glycogen. We conclude that intermittent hypoxia maintains glycemia in streptozotocin-induced diabetic rats and its regulation on muscular glycogenesis may play a role in the underlying mechanism. PMID:26902078

  19. Estrogen Receptor α Is Required for Maintaining Baseline Renin Expression.

    Science.gov (United States)

    Lu, Ko-Ting; Keen, Henry L; Weatherford, Eric T; Sequeira-Lopez, Maria Luisa S; Gomez, R Ariel; Sigmund, Curt D

    2016-05-01

    Enzymatic cleavage of angiotensinogen by renin represents the critical rate-limiting step in the production of angiotensin II, but the mechanisms regulating the initial expression of the renin gene remain incomplete. The purpose of this study is to unravel the molecular mechanism controlling renin expression. We identified a subset of nuclear receptors that exhibited an expression pattern similar to renin by reanalyzing a publicly available microarray data set. Expression of some of these nuclear receptors was similarly regulated as renin in response to physiological cues, which are known to regulate renin. Among these, only estrogen receptor α (ERα) and hepatic nuclear factor α have no known function in regulating renin expression. We determined that ERα is essential for the maintenance of renin expression by transfection of small interfering RNAs targeting Esr1, the gene encoding ERα, in renin-expressing As4.1 cells. We also observed that previously characterized negative regulators of renin expression, Nr2f2 and vitamin D receptor, exhibited elevated expression in response to ERα inhibition. Therefore, we tested whether ERα regulates renin expression through an interaction with Nr2f2 and vitamin D receptor. Renin expression did not return to baseline when we concurrently suppressed both Esr1 and Nr2f2 or Esr1 and vitamin D receptor mRNAs, strongly suggesting that Esr1 regulates renin expression independent of Nr2f2 and vitamin D receptor. ERα directly binds to the hormone response element within the renin enhancer region. We conclude that ERα is a previously unknown regulator of renin that directly binds to the renin enhancer hormone response element sequence and is critical in maintaining renin expression in renin-expressing As4.1 cells. PMID:26928806

  20. Management of wound infection after lumbar arthrodesis maintaining the instrumentation

    Directory of Open Access Journals (Sweden)

    Asdrubal Falavigna

    2015-06-01

    Full Text Available OBJECTIVE: To determinate whether a surgical protocol with immediate extensive debridement, closed irrigation system and antibiotic therapy would be effective to achieve healing of deep wound infection without removing the instrumentation.METHODS: Prospective cohort study with 19 patients presenting degenerative spinal stenosis or degenerative spondylolisthesis, who developed infection after posterior lumbar arthrodesis. The diagnosis was confirmed by a microbial culture from subfascial lumbar fluid and/or blood. Patients were treated with a protocol of wound exploration, extensive flushing and debridement, placement of a closed irrigation system that was maintained for five days and intravenous antibiotics. The instrumentation system was not removed.RESULTS: Mean age was 59.31 (±13.17 years old and most patients were female (94.7%; 18/19. The mean period for the identification of the infection was 2 weeks and 57.9% underwent a single wound exploration. White blood count, erythrocyte sedimentation rate and C-reactive protein showed a significant decrease post-treatment when compared to pre-treatment values. A significant reduction of erythrocyte sedimentation rate and C-reactive protein was also observed at the final evaluation. No laboratory test was useful to predict the need for more than one debridement.CONCLUSION: Patients with wound infection after instrumentation can be treated without removal of the instrumentation through wound exploration, extensive flushing, debridement of necrotic tissue, closed irrigation system during 5 days and proper antibiotic therapy. The blood tests were not useful to predict surgical re-interventions.

  1. Maintaining staff competence-a NPP operator viewpoint

    International Nuclear Information System (INIS)

    For a nuclear power plant operator, it is crucial to guarantee the safe and economic operation of the power plant as well as to look after the general acceptability of nuclear power. As to human resources management, this requires continuous maintenance and enhancement of the performance of the individuals and organisation. To this end, several development projects have recently been implemented by Teollisuuden Voima Oy (TVO) at the Olkiluoto nuclear power plant, which consists of twin 840 MWe BWR units that commenced their operation in 1978 and 1980. Systematic initial and continuing training programmes are needed to maintain the technical and managerial skills and know-how at a high level. The present stabile state of nuclear power, i.e. operation of ageing plants with personnel ageing as well, requires a variety of actions to reinforce the training efforts. At Olkiluoto NPP, we have carried out an extensive modernization programme that allowed the personnel to strengthen their knowledge and supplement it with the most recent results of development. We have also closely monitored the NPP development projects of the vendors, which has added to the preservation of know-how and understanding of advanced nuclear power technology. We have close contacts to the research institutes and universities, and have performed R and D activities to limited extent. In addition to the projects mentioned above, a co-ordinated development programme, 'TVO 2002', was initiated last year. The main objective of this programme is to ensure the functional preconditions and the competitiveness of the company in a changing environment. The management and operational procedures will be developed in such a way that the goals set for year 2002 will be achieved. The programme is organised as ten projects, which cover a variety of development subjects. One of the focal areas includes projects that can be characterised with the words 'Survey of competencies' and 'Preservation of know

  2. Maintaining cholesterol homeostasis:Sterol regulatory element-binding proteins

    Institute of Scientific and Technical Information of China (English)

    Lutz W. Weber; Meinrad Boll; Andreas Stampfl

    2004-01-01

    The molecular mechanism of how hepatocytes maintain cholesterol homeostasis has become much more transparent with the discovery of sterol regulatory element binding proteins (SREBPs) in recent years. These membrane proteins are members of the basic helix-loop-helix-leucine zipper (bHLHZip) family of transcription factors. They activate the expression of at least 30 genes involved in the synthesis of cholesterol and lipids. SREBPs are synthesized as precursor proteins in the endoplasmic reticulum (ER), where they form a complex with another protein, SREBP cleavage activating protein (SCAP).The SCAP molecule contains a sterol sensory domain. In the presence of high cellular sterol concentrations SCAP confines SREBP to the ER. With low cellular concentrations, SCAP escorts SREBP to activation in the Golgi. There, SREBP undergoes two proteolytic cleavage steps to release the mature, biologically active transcription factor, nuclear SREBP (nSREBP). nSREBP translocates to the nucleus and binds to sterol response elements (SRE) in the promoter/enhancer regions of target genes. Additional transcription factors are required to activate transcription of these genes. Three different SREBPs are known, SREBPs-1a, -1c and -2. SREBP-1a and -1c are isoforms produced from a single gene by alternate splicing. SREBP-2is encoded by a different gene and does not display any isoforms. It appears that SREBPs alone, in the sequence described above, can exert complete control over cholesterol synthesis, whereas many additional factors (hormones,cytokines, etc.) are required for complete control of lipid metabolism. Medicinal manipulation of the SREBP/SCAP system is expected to prove highly beneficial in the management of cholesterol-related disease.

  3. Human STEAP3 maintains tumor growth under hypoferric condition

    Energy Technology Data Exchange (ETDEWEB)

    Isobe, Taichi, E-mail: tisobe@intmed1.med.kyushu-u.ac.jp [Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582 (Japan); Baba, Eishi, E-mail: e-baba@intmed1.med.kyushu-u.ac.jp [Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582 (Japan); Arita, Shuji, E-mail: arita.s@nk-cc.go.jp [Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582 (Japan); Komoda, Masato, E-mail: komoda@intmed1.med.kyushu-u.ac.jp [Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582 (Japan); Tamura, Shingo, E-mail: tamshin@intmed1.med.kyushu-u.ac.jp [Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582 (Japan); Shirakawa, Tsuyoshi, E-mail: t-w-r@intmed1.med.kyushu-u.ac.jp [Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582 (Japan); Ariyama, Hiroshi, E-mail: hariyama@kyumed.jp [Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582 (Japan); Takaishi, Shigeo, E-mail: takaishi@med.kyushu-u.ac.jp [Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582 (Japan); Kusaba, Hitoshi, E-mail: hkusaba@intmed1.med.kyushu-u.ac.jp [Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582 (Japan); and others

    2011-11-01

    Iron is essential in cellular proliferation and survival based on its crucial roles in DNA and ATP synthesis. Tumor cells proliferate rapidly even in patients with low serum iron, although their actual mechanisms are not well known. To elucidate molecular mechanisms of efficient tumor progression under the hypoferric condition, we studied the roles of six-transmembrane epithelial antigen of the prostate family member 3 (STEAP3), which was reported to facilitate iron uptake. Using Raji cells with low STEAP3 mRNA expression, human STEAP3-overexpressing cells were established. The impact of STEAP3 expression was analyzed about the amount of iron storage, the survival under hypoferric conditions in vitro and the growth of tumor in vivo. STEAP3 overexpression increased ferritin, an indicator of iron storage, in STEAP3-overexpressing Raji cells. STEAP3 gave Raji cells the resistance to iron deprivation-induced apoptosis. These STEAP3-overexpressing Raji cells preserved efficient growth even in hypoferric mice, while parental Raji cells grew less rapidly. In addition, iron deficiency enhanced STEAP3 mRNA expression in tumor cells. Furthermore, human colorectal cancer tissues exhibited more STEAP3 mRNA expression and iron storage compared with normal colon mucosa. These findings indicate that STEAP3 maintains iron storage in human malignant cells and tumor proliferation under the hypoferric condition. -- Highlights: {yields} STEAP3 expression results in increment of stored intracellular iron. {yields} Iron deprivation induces expression of STEAP3. {yields} Colorectal cancer expresses STEAP3 highly and stores iron much. {yields} STEAP3 expressing tumors preserves growth even in mice being hypoferremia.

  4. Genetic and somatic effects in animals maintained on tritiated water

    International Nuclear Information System (INIS)

    Somatic and genetic effects of the continuous ingestion of tritiated water (HTO) at concentrations of 0.3, 1.0 and 3.0 μCi/ml were investigated in mice of the Hale-Stoner-Brookhaven strain. At these levels, there was no measurable somatic effect. Although genetic effects as measured by dominant lethal mutation (DLM) assay indicated a significant effect (P>0.01) on the number of viable embryos and early deaths in the 3.0 μCi/ml HTO group and on the number of viable embryos in the 1.0 μCi/ml HTO group, no genetic effects were significantly noted in the 0.3 μCi/ml HTO group. Liver cytogenetic studies showed a significant increase in the number of abnormal cells in the 3.0 μCi/ml HTO group. A reduction in bone marrow stem cells, without an attendant reduction in total marrow cellularity, was noted in the 3.0 and 1.0 μCi/ml HTO groups. There was no significant difference in any of the DLM parameters between animals maintained on 3.0 μCi/ml of HTO and animals exposed to the equivalent 137Cs gamma dose (22 hours/day exposure). Consideration of the relative amounts and biological half lives of tritium present in the nucleus as water, DNA and histone suggests that after transient exposure to tritiated water, nearly all significant radiation damage can be attributed to tritium present in the nucleus as water. These data suggest that hazards from tritium attendant with normal reactor operation should not at this time be considered as a deterrent to the further development of fission and/or fusion reactor technology. (Namekawa, K.)

  5. Maintaining Mission Critical Systems in a 247 Environment

    CERN Document Server

    Curtis, Peter M

    2011-01-01

    "This book is meant to offer Architects, Property Mangers, Facility Managers, Building Engineers, Information Technology Professionals, Data Center Personnel, Electrical & Mechanical Technicians and students in undergraduate, graduate, or continuing education programs relevant insight into the Mission Critical Environment with an emphasis on business resiliency, data center efficiency, and green power technology. Industry improvements, standards, and techniques have been incorporated into the text and address the latest issues prevalent in the Mission Critical Industry. An emphasis on green technologies and certifications is presented throughout the book. In addition, a description of the United States energy infrastructure's dependency on oil, in relation to energy security in the mission critical industry, is discussed. In conjunction with this, either a new chapter will be created on updated policies and regulations specifically related to the mission critical industry or updates to policies and regula...

  6. Forward Capacity Markets: Maintaining Grid Reliability in Europe

    OpenAIRE

    Chaigneau, Matthieu

    2012-01-01

    The liberalization process of the electricity industry in many countries leads to new rules and new challenges for the grid management. System reliability is a major concern, mainly because of (a) the high level penetration of renewable energy sources and (b) the growing peak load and environmental regulations In most electricity markets, peak resources operate only during a short period, and at a high operating cost, jeopardizing their return on investment, while low-cost base resources make...

  7. Whether depositing fat or losing weight, fish maintain a balance

    OpenAIRE

    Brix, Ole; Grüner, Renate; Rønnestad, Ivar; Gemballa, Sven

    2009-01-01

    In fish, the relative amount of tissues of different densities changes significantly over short periods throughout the year, depending on the availability of food, nutrition and their developmental status, such as sexual maturation. If a land-living animal accumulates fat it influences not only its general state of health, but also markedly increases its energy expenditure for locomotion owing to the force of gravity. On a body submerged in water, this force, which acts on the centre of gravi...

  8. Ways to maintain nuclear safety competence in Finland

    International Nuclear Information System (INIS)

    In mid-1990's, both Finnish nuclear power operators started extensive plant modernization. National surveys indicated that the present age distribution of nuclear power experts implies shortage of resources through retirement within 10 years, unless education is timely enhanced. The current rate of nuclear energy specific education, about 10 master's degrees per year, will be too low, particularly if construction of new nuclear capacity were started. The problem is recognised, and some measures have been initiated. In Finland continued public funding for nuclear energy research is judged important to assure impartial expertise for the safety authorities. This research has been organised as national research programmes, where the requirement to raise experts is emphasised. Challenging tasks have proved to be important in motivating the students and the permanent personnel. The specific features of the VVER reactors, participation in international R and D projects and, recently, design and assessment of ALWR concepts have offered such possibilities. The image of nuclear energy affects the interest of young generation when choosing a career. One way to improve the situation is to increase communication with the public and direct information to the potential students. The need for other than technical skills is also reflected in the latest work programme of the Young Generation Network, organised by the Finnish Nuclear Society. (authors)

  9. Differential Proteomic Analysis of Anthers between Cytoplasmic Male Sterile and Maintainer Lines in Capsicum annuum L.

    Directory of Open Access Journals (Sweden)

    Zhiming Wu

    2013-11-01

    Full Text Available Cytoplasmic male sterility (CMS, widely used in the production of hybrid seeds, is a maternally inherited trait resulting in a failure to produce functional pollen. In order to identify some specific proteins associated with CMS in pepper, two-dimensional gel electrophoresis (2-DE was applied to proteomic analysis of anthers/buds between a CMS line (designated NA3 and its maintainer (designated NB3 in Capsicum annuum L. Thirty-three spots showed more than 1.5-fold in either CMS or its maintainer. Based on mass spectrometry, 27 spots representing 23 distinct proteins in these 33 spots were identified. Proteins down-regulated in CMS anthers/buds includes ATP synthase D chain, formate dehydrogenase, alpha-mannosidas, RuBisCO large subunit-binding protein subunit beta, chloroplast manganese stabilizing protein-II, glutathione S-transferase, adenosine kinase isoform 1T-like protein, putative DNA repair protein RAD23-4, putative caffeoyl-CoA 3-O-methyltransferase, glutamine synthetase (GS, annexin Cap32, glutelin, allene oxide cyclase, etc. In CMS anthers/buds, polyphenol oxidase, ATP synthase subunit beta, and actin are up-regulated. It was predicted that male sterility in NA3 might be related to energy metabolism turbulence, excessive ethylene synthesis, and suffocation of starch synthesis. The present study lays a foundation for future investigations of gene functions associated with pollen development and cytoplasmic male sterility, and explores the molecular mechanism of CMS in pepper.

  10. Understanding how replication processes can maintain systems away from equilibrium using Algorithmic Information Theory.

    Science.gov (United States)

    Devine, Sean D

    2016-02-01

    Replication can be envisaged as a computational process that is able to generate and maintain order far-from-equilibrium. Replication processes, can self-regulate, as the drive to replicate can counter degradation processes that impact on a system. The capability of replicated structures to access high quality energy and eject disorder allows Landauer's principle, in conjunction with Algorithmic Information Theory, to quantify the entropy requirements to maintain a system far-from-equilibrium. Using Landauer's principle, where destabilising processes, operating under the second law of thermodynamics, change the information content or the algorithmic entropy of a system by ΔH bits, replication processes can access order, eject disorder, and counter the change without outside interventions. Both diversity in replicated structures, and the coupling of different replicated systems, increase the ability of the system (or systems) to self-regulate in a changing environment as adaptation processes select those structures that use resources more efficiently. At the level of the structure, as selection processes minimise the information loss, the irreversibility is minimised. While each structure that emerges can be said to be more entropically efficient, as such replicating structures proliferate, the dissipation of the system as a whole is higher than would be the case for inert or simpler structures. While a detailed application to most real systems would be difficult, the approach may well be useful in understanding incremental changes to real systems and provide broad descriptions of system behaviour. PMID:26723233

  11. Should we maintain baby hatches in our society?

    Directory of Open Access Journals (Sweden)

    Asai Atsushi

    2013-02-01

    Full Text Available Abstract Background A baby hatch called the “Stork’s Cradle” has been in place at Jikei Hospital in Kumamoto City, Japan, since May 10, 2007. Babyklappes were first established in Germany in 2000, and there are currently more than 90 locations. Attitudes regarding baby hatches are divided in Japan and neither opinions for nor against baby hatches have thus far been overwhelming. To consider the appropriateness of baby hatches, we present and examine the validity of each major objection to establishing baby hatches. Discussion There are various objections to baby hatches as follows: It violates a child’s right to know the identity of his or her biological parents by allowing anonymous birth; it neglects fulfillment of the biological parents’ basic obligation to raise their child and its very availability induces abandonment of infants; some people abuse it for very selfish reasons; it cannot save babies’ lives; the rights of one parent can be ignored if the other surrenders a child without his or her consent; it puts a baby in medical jeopardy; and it has no clear legal basis. The authors would argue that there are many plausible refutations for each objection mainly based on priority of child’s right to life, pregnant women’s vulnerability and necessity of anonymity, social responsibility to protect and raise children, differences between dropping a child off at a baby hatch and child neglect, limited function of social childcare center, inevitability of abuse by a minority of people, necessary distinction between outcomes that occur only because baby hatches exist and those that occur regardless of their existence, important local direct and upmost measures for women in trouble, and difference between ambiguous legality and illegality. Summary We argue that a certain number of baby hatches should continue to be established as a last resort, in a form that can maintain anonymity if the parent dropping the child off so desires. It

  12. Hanford Site Guide for Preparing and Maintaining Generator Group Pollution Prevention Documentation

    International Nuclear Information System (INIS)

    This document provides guidance to generator groups for preparing and maintaining documentation of Pollution Prevention/Waste Minimization (P2/WMin) Program activities. The guidance is one of a hierarchical series that includes the Hanford Site Waste Minimization and Pollution Prevention Awareness Program Plan (DOE-RL, 2000) and Prime Contractor implementation plans describing programs required by Resource Conservation and Recovery Act of 1976 (RCRA) 3002(b) and 3005(h) (RCRA and EPA, 1994) and Department of Energy Acquisition Regulations (DEAR) (48 CFR 970.5204-2 and 48 CFR 970.5204-78). Documentation guidance for the following five P2/WMin elements is discussed: Fiscal Year (FY) Goals; Budget and Staffing; Pollution Prevention (P2) Reporting; WMin Certification; and Waste Minimization (WMin) Assessments (WMAs)

  13. Hanford Site Guide for Preparing and Maintaining Generator Group Pollution Prevention Program Documentation

    International Nuclear Information System (INIS)

    This document provides guidance to generator groups for preparing and maintaining documentation of Pollution Prevention/Waste Minimization (P2/WMin) hogram activities. The guidance is one of a hierarchical series that includes the ''Hanford Site Waste Minimization and Pollution Prevention Awareness Program Plan'' (DOE-RL, 2001) and Prime Contractor implementation plans describing programs required by ''Resource Conservation and Recovery Act of 1976'' (RCRA) 3002(b) and 3005(h) (RCRA and EPA, 1994) and Department of Energy Acquisition Regulations (DEAR) (48 CFR 970.5204-2 and 48 CFR 970.5204-78). Documentation guidance for the following five P2/WMin elements is discussed: (1) Fiscal Year (FY) Goals; (2) Budget and Staffing; (3) Waste Minimization (WMin) Assessments (WMAs); (4) Pollution Prevention (P2) Reporting; and (5) WMin Certification

  14. Polarization-maintaining fiber pulse compressor by birefringent hollow-core photonic bandgap fiber.

    Science.gov (United States)

    Shirakawa, Akira; Tanisho, Motoyuki; Ueda, Ken-Ichi

    2006-12-11

    Structural birefringent properties of a hollow-core photonic-bandgap fiber were carefully investigated and applied to all-fiber chirped-pulse amplification as a compressor. The group birefringence of as high as 6.9x10(-4) and the dispersion splitting by as large as 149 ps/nm/km between the two principal polarization modes were observed at 1557 nm. By launching the amplifier output to one of the polarization modes a 17-dB polarization extinction ratio was obtained without any pulse degradation originating from polarization-mode dispersion. A hybrid fiber stretcher effectively compensates the peculiar dispersion of the photonic-bandgap fiber and pedestal-free 440-fs pulses with a 1-W average power and 21-nJ pulse energy were obtained. Polarization-maintaining fiber-pigtail output of high-power femtosecond pulses is useful for various applications. PMID:19529631

  15. Hanford Site Guide for Preparing and Maintaining Generator Group Pollution Prevention Program Documentation

    Energy Technology Data Exchange (ETDEWEB)

    PLACE, B.G.

    2000-11-01

    This document provides guidance to generator groups for preparing and maintaining documentation of Pollution Prevention/Waste Minimization (P2/WMin) Program activities. The guidance is one of a hierarchical series that includes the Hanford Site Waste Minimization and Pollution Prevention Awareness Program Plan (DOE-RL, 2000) and Prime Contractor implementation plans describing programs required by Resource Conservation and Recovery Act of 1976 (RCRA) 3002(b) and 3005(h) (RCRA and EPA, 1994) and Department of Energy Acquisition Regulations (DEAR) (48 CFR 970.5204-2 and 48 CFR 970.5204-78). Documentation guidance for the following five P2/WMin elements is discussed: Fiscal Year (FY) Goals; Budget and Staffing; Pollution Prevention (P2) Reporting; WMin Certification; and Waste Minimization (WMin) Assessments (WMAs).

  16. 34-fs, all-fiber all-polarization-maintaining single-mode pulse nonlinear amplifier.

    Science.gov (United States)

    Yu, Jia; Feng, Ye; Cai, Yajun; Li, Xiaohui; Hu, Xiaohong; Zhang, Wei; Duan, Lina; Yang, Zhi; Wang, Yishan; Liu, Yuanshan; Zhao, Wei

    2016-07-25

    We present an all-fiber all-polarization-maintaining (PM) single mode (SM) fiber pulse nonlinear amplification system. The seed laser with a repetition rate of 200 MHz is amplified by two-section erbium-doped PM gain fibers with different peak-absorption rate. The amplified pulse duration can be compressed into 34-fs with 320-mW output power, which corresponds to 1.6-nJ pulse energy and approximate 23.5-kW peak power. In addition, the amplified and compressed pulse is further coupled into the high nonlinear fiber and an octave-spanning supercontinuum generation can be obtained. To the best of our knowledge, it is the highest peak power and the shortest pulse duration obtained in the field of all-fiber all-PM SM pulse-amplification systems. PMID:27464117

  17. Evaluating the Maintainability of a Software System by using Fuzzy Logic Approach

    Directory of Open Access Journals (Sweden)

    Ritika Vern

    2014-12-01

    Full Text Available Maintainability is an important quality attribute for almost every quality model. Maintainability of the software is considered as most expensive phase in software development life cycle as it consumes almost major part of the total effort allocated to the software system. Maintainability evaluation is complex due to its imprecise output. This paper proposes a maintainability model by considering its fuzzy aspects. Since fuzzy modeling deals with uncertainty and impreciseness so this paper uses fuzzy methodology and AHP technique to evaluate the maintainability of the model. Object oriented system has taken as case study for maintainability evaluation purpose.

  18. Virtual Oscillator Control Maintains Grid Operations with High Inverter Penetrations

    Energy Technology Data Exchange (ETDEWEB)

    2016-06-01

    VOC makes each inverter behave electrically like a spring, 'bouncing back' to its normal operating range when disturbed. Coupling these inverters electronically could result in a new way to stabilize power grids. VOC has been demonstrated in a microgrid using several small inverters. In addition, five custom-designed inverters have been built and will be tested with grid simulations at NREL using power hardware-in-the-loop technology. VOC may provide a simple method to keep microgrids stable -- a topic of growing interest as resilience to energy disruptions gains prominence. VOC may also provide a means to transition power grids from today's inertia-dominated systems to systems that do not rely on rotating machinery.

  19. Priorities Outlined for Maintaining China’s Sustainable Economic Growth

    Institute of Scientific and Technical Information of China (English)

    张国有

    2007-01-01

    The next 15 years will continue to witness the rapid economic rise of China,with an emphasis on both quality and speed.In the first half of the 21st century,rural areas remain to be the"strategic citadel"of expanding domestic demand and economic growth.In the face of energy and resource challenges,China plans to lay the groundwork of a resource-efficient society in 30 years.Other priorities include:building a favourable environment for international exchange,persisting in the path of"bringing-in,going global"and advancing international competition and cooperation based on mutual benefit and win-win situations.Moreover,to pursue independent innovation,develop private-run businesses,and engage the initiative of both local government and enterprises to enhance China’s economic vibrancy and sustainable growth.

  20. Whether depositing fat or losing weight, fish maintain a balance.

    Science.gov (United States)

    Brix, Ole; Grüner, Renate; Rønnestad, Ivar; Gemballa, Sven

    2009-11-01

    In fish, the relative amount of tissues of different densities changes significantly over short periods throughout the year, depending on the availability of food, nutrition and their developmental status, such as sexual maturation. If a land-living animal accumulates fat it influences not only its general state of health, but also markedly increases its energy expenditure for locomotion owing to the force of gravity. On a body submerged in water, this force, which acts on the centre of gravity (COG), is counterbalanced by a lifting force that is negligible in air and which acts on the centre of buoyancy (COB). Any difference in the longitudinal positions of the two centres will therefore result in pitching moments that must be counteracted by body or fin movements. The displacement of the COG away from the COB is a result of tissues of different density (e.g. bones and fat) not being distributed homogeneously along the body axis. Moreover, the proportions of tissues of different densities change significantly with feeding status. It is still unknown whether these changes produce a displacement of the COG and thus affect the hydrostatic stability of fish. Analysis of computed tomography and magnetic resonance imaging images of Atlantic herring, Atlantic salmon and Atlantic mackerel reveals that the COG is fairly constant in each species, although we recorded major interspecies differences in the relative amount of fat, muscle and bone. We conclude that the distribution of different tissues along the body axis is very closely adjusted to the swimming mode of the fish by keeping the COG constant, independent of the body fat status, and that fish can cope with large variations in energy intake without jeopardizing their COG and thus their swimming performance. PMID:19675008

  1. Tractor Mechanics. Maintaining and Servicing the Cooling System, Learning Activity Packages 34-40; Maintaining and Servicing Hydraulic Systems, Learning Activity Packages 41-48.

    Science.gov (United States)

    Clemson Univ., SC. Vocational Education Media Center.

    This series of learning activity packages focuses on two areas of tractor mechanics: (1) maintaining and servicing the cooling system and (2) maintaining and servicing hydraulic systems. Each of the fifteen illustrated learning activity packages follows a typical format: introduction, directions, objectives, learning activities, tools and…

  2. Measures geared to maintain the competence of operating personnel at Grohnde nuclear power plant

    International Nuclear Information System (INIS)

    Organizational structure of the German power plant 'Gemeinschaftskernkraftwerk Grohnde GmbH'. The plant characteristics of the tasks and duties and definition of competence. Measures to maintain competence. The experience by the realization of training programs to maintain competence. (orig.)

  3. Evaluating the Maintainability of a Software System by using Fuzzy Logic Approach

    OpenAIRE

    Ritika Vern; Sanjay Kumar Dubey

    2014-01-01

    Maintainability is an important quality attribute for almost every quality model. Maintainability of the software is considered as most expensive phase in software development life cycle as it consumes almost major part of the total effort allocated to the software system. Maintainability evaluation is complex due to its imprecise output. This paper proposes a maintainability model by considering its fuzzy aspects. Since fuzzy modeling deals with uncertainty and impreciseness so this paper us...

  4. Maintaining a Distinction Between Possible and Impossible Topics of Conversation in the Outpatient Respiratory Medical Clinic

    DEFF Research Database (Denmark)

    Birgitte Skov Jensen,, lone; Konradsen, Hanne; Larsen, Kristian

    interaction by maintaining a distinction between possible and impossible topics to counseling. Three subcategories explaining the effort that maintain the impossible and possible topics separated were identified: (a) an effort to maintain the diseased lungs as the main task in counseling, (b) navigating...

  5. 29 CFR 2530.210 - Employer or employers maintaining the plan.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Employer or employers maintaining the plan. 2530.210... Administration as Related to Benefits § 2530.210 Employer or employers maintaining the plan. (a) General... service with the employer or employers maintaining the plan shall be taken into account for purposes...

  6. 77 FR 27533 - Application for Presidential Permit To Construct, Operate and Maintain Pipeline Facilities on the...

    Science.gov (United States)

    2012-05-10

    ... Application for Presidential Permit To Construct, Operate and Maintain Pipeline Facilities on the Border of... Presidential Permit to Construct, Operate and Maintain Pipeline Facilities on the Border of the United States... construct, operate and maintain pipeline facilities on the border of the United States from...

  7. Maintaining a Distinction Between Possible and Impossible Topics of Conversation in the Outpatient Respiratory Medical Clinic

    DEFF Research Database (Denmark)

    Birgitte Skov Jensen, Lone; Larsen, Kristian; Konradsen, Hanne

    2016-01-01

    maintaining a distinction between possible and impossible topics to counseling. Three subcategories explaining the effort that maintain the impossible and possible topics separated were identified: (a) an effort to maintain the diseased lungs as the main task in counseling, (b) navigating interactions to...

  8. Pipe rules: regulators, industry work together to maintain safety

    Energy Technology Data Exchange (ETDEWEB)

    Budd, G.

    2002-10-01

    Two tragic pipeline explosions in the United States in recent years focused attention on pipeline regulations both in the United States as well as in Canada. In the United States regulations tend to be highly prescriptive, especially in the aftermath of the two explosions. In Canada, there appears to be a sharper focus on the goal of pipeline safety, with regulators encouraging companies to come up with their own set of specifics for achieving it. The Canadian National Energy Board, the regulatory body, places the emphasis on integrity management, encouraging the industry to be more systematic in its approach to the problem. Industry response to the NEB initiative has been positive as shown by the responses of various pipeline and pipeline service companies. For example, NeoCorr Engineering Ltd., produced its web-enabled proprietary software program called OCELOT (online corrosion evaluation tool). The firm has been providing corrosion evaluation, flow modelling and related services for some time; as of this year, the service is also available online. NeoCorr's services are directed to address the technical needs of pipeline operators concerned about quality maintenance in the current non-prescriptive integrity management climate. The system captures all operating data, physical location, shape and terrain of line; these provide the basis for a flow model and a digital pipeline elevation profile. On the basis of this, the process provides information on the likelihood of corrosion and any other integrity issues, which then triggers the maintenance plan that is tailored to the profile. Because the cost of state-of-the-art detection technology is high, small and new companies are often reluctant to avail themselves of these services, but pipelines companies with thousands of flow lines and collectors in service have all the incentive needed to perform maintenance. Improvements in internal logging and crack detection tools also helped to improve attention to

  9. Adipocyte insulin receptor activity maintains adipose tissue mass and lifespan.

    Science.gov (United States)

    Friesen, Max; Hudak, Carolyn S; Warren, Curtis R; Xia, Fang; Cowan, Chad A

    2016-08-01

    Type 2 diabetes follows a well-defined progressive pathogenesis, beginning with insulin resistance in metabolic tissues such as the adipose. Intracellular signaling downstream of insulin receptor activation regulates critical metabolic functions of adipose tissue, including glucose uptake, lipogenesis, lipolysis and adipokine secretion. Previous studies have used the aP2 promoter to drive Cre recombinase expression in adipose tissue. Insulin receptor (IR) knockout mice created using this aP2-Cre strategy (FIRKO mice) were protected from obesity and glucose intolerance. Later studies demonstrated the promiscuity of the aP2 promoter, casting doubts upon the tissue specificity of aP2-Cre models. It is our goal to use the increased precision of the Adipoq promoter to investigate adipocyte-specific IR function. Towards this end we generated an adipocyte-specific IR knockout (AIRKO) mouse using an Adipoq-driven Cre recombinase. Here we report AIRKO mice are less insulin sensitive throughout life, and less glucose tolerant than wild-type (WT) littermates at the age of 16 weeks. In contrast to WT littermates, the insulin sensitivity of AIRKO mice is unaffected by age or dietary regimen. At any age, AIRKO mice are comparably insulin resistant to old or obese WT mice and have a significantly reduced lifespan. Similar results were obtained when these phenotypes were re-examined in FIRKO mice. We also found that the AIRKO mouse is protected from high-fat diet-induced weight gain, corresponding with a 90% reduction in tissue weight of major adipose depots compared to WT littermates. Adipose tissue mass reduction is accompanied by hepatomegaly and increased hepatic steatosis. These data indicate that adipocyte IR function is crucial to systemic energy metabolism and has profound effects on adiposity, hepatic homeostasis and lifespan. PMID:27246738

  10. Designing for nuclear power plant maintainability and operability

    International Nuclear Information System (INIS)

    Experience has shown that maintenance and operability aspects must be addressed in the design work. ABB Atom has since long an ambition of achieving optimised, overall plant designs, and efficient feedback of growing operating experience has stepwise eliminated shortcomings, and yielded better and better plant operating performances. The records of the plants of the latest design versions are very good; four units in Sweden have operated at an energy availability of 90.1%, and the two Olkiluoto units in Finland at a load factor of 92.7%, over the last decade. The occupational radiation exposures have also been at a low level. The possibilities for implementing 'lessons learned' in existing plants are obviously limited by practical constraints. In Finland and Sweden, significant modernisations are still underway, however, involving replacement of mechanical equipment, and upgrading and backfitting of I and C systems on a large scale, in most of the plants. The BWR 90 design focuses on meeting requirements from utilities as well as new regulatory requirements, with a particular emphasis on the consequences of severe accidents; there shall be no large releases to the environment. Other design improvements involve: all-digital I and C systems and enhanced human factors engineering to improve work environment for operators, optimisation of buildings and containment to decrease construction time and costs, and selection of materials as well as maintenance of operating procedures to reduce radiation exposures even further. The BWR 90 design was offered to Finland in the early 1990s, but development work continues. It has been selected by a number of European utilities for assessing its conformance with the European Utility Requirements (EUR), aiming at a specific EUR Volume 3 for the BWR 90. Some characteristics of the ABB BWRs, with emphasis on features of importance for achieving improved economy and enhanced safety, are described below. (author)

  11. Alloy-Enhanced Fans Maintain Fresh Air in Tunnels

    Science.gov (United States)

    2012-01-01

    The Partnership for Next Generation Vehicles (PNGV) is not a NASA initiative to develop powerful new rockets and spacecraft, even though it may sound like one. PNGV was a partnership established by the Clinton administration between the Federal government and the U.S. Council for Automotive Research to develop technologies that improve fuel efficiency and reduce emissions from cars and trucks. More than 20 Federal laboratories from the Departments of Commerce, Energy, Transportation, and Defense; the Environmental Protection Agency; the National Science Foundation; and NASA were all involved in PNGV, in addition to more than 350 automotive suppliers, universities, and small businesses. In support of this tremendous effort, Jonathan Lee, a materials engineer at Marshall Space Flight Center, worked with a major automobile manufacturer in 1995 to develop a strong aluminum alloy for high temperature applications. The aim was to use the alloy for manufacturing parts for an internal combustion engine, as well as for NASA s propulsion applications. When funding from PNGV ended, Marshall continued to support the alloy s development with help from NASA s Innovative Partnerships Program (now the Office of the Chief Technologist). Together with PoShou Chen, a scientist with Morgan Research Corporation, Lee invented a highstrength aluminum alloy called MSFC-398 that, when tested, was three to four times stronger than conventional aluminum alloys at high temperatures. By the late 1990s, Lee says, NASA s scientists had successfully developed and patented this technology, which has great potential applications not for just automotive, but also for aerospace, marine, and commercial applications

  12. Maintainability Estimation Model for Object-Oriented Software in Design Phase (MEMOOD)

    CERN Document Server

    Rizvi, S W A

    2010-01-01

    Measuring software maintainability early in the development life cycle, especially at the design phase, may help designers to incorporate required enhancement and corrections for improving maintainability of the final software. This paper developed a multivariate linear model 'Maintainability Estimation Model for Object-Oriented software in Design phase' (MEMOOD), which estimates the maintainability of class diagrams in terms of their understandability and modifiability. While, in order to quantify class diagram's understandability and modifiability the paper further developed two more multivariate models. These two models use design level object-oriented metrics, to quantify understandability and modifiability of class diagram. Such early quantification of maintainability provides an opportunity to improve the maintainability of class diagram and consequently the maintainability of final software. All the three models have been validated through appropriate statistical measures and contextual interpretation ...

  13. Solar photovoltaic energy

    CERN Document Server

    Labouret, Anne

    2010-01-01

    Providing designers, installers and managers with the tools and methods for the effective writing of technical reports and the ability to calculate, install and maintain the necessary components of photovoltaic energy.

  14. Designing a Comprehensive Model for Evaluating SOA-based Services Maintainability

    OpenAIRE

    Maryam Zarrin; Mir Ali Seyyedi; Mehran Mohsenzaeh

    2011-01-01

    The aim of this paper is to propose a comprehensive and practical model to evaluate the maintainability of software services in service-oriented architecture in the entire service lifecycle and based on the fuzzy system. This model provides the possibility of making decisions concerning the maintainability of SOA-based services for service managers and owners in various service operation and design phases. The proposed maintainability evaluation model consists of five sections: input, analysi...

  15. Maintaining Confidence

    OpenAIRE

    David Murphy

    2012-01-01

    This paper proposes the solvency/liquidity spiral as an failure mode affecting large financial institutions in the recent crisis. The essential features of this mode are that a combination of funding liquidity risk and investor doubts over the solvency of an institution can lead to its failure. We analyse the failures of Lehman Brothers and RBS in detail, and find considerable support for the spiral model of distress. Our model suggests that a key determinant of the financial stability of man...

  16. Maintaining Growth

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    China's GDP grew 9.2 percent in 2011,a remarkable achievement outshining many other countries.However,the current condition of the national economy is less than appealing.The sequential quarterly GDP growth rates for 2011 stood at 9.7 percent,9.5 percent,9.1 percent and 8.9 percent,showing a trend of deceleration.A consensus has been made that stabilizing growth should be the primary goal for China's economic development.

  17. Software maintainability

    OpenAIRE

    Leppänen, Väinö

    2011-01-01

    Tämän opinnäytetyön tarkoitus oli kohottaa erään tietyn ohjelmiston ylläpidettävyyttä. Työ käsittelee kyseistä olio-pohjaista ohjelmistoa pääasiallisesti luokka-tasolla. Kyseessä on toiminnallinen opinnäytetyö, joka alkoi kirjallisuuteen tutustumalla. Vuoden 2011 ensimmäisen puoliskon aikana ohjelmiston ylläpidettävyyttä kohotettiin käymällä sen rakennetta läpi samalla analysoiden sen kelvollisuutta. Rakenne käytiin läpi aloittaen luokkatasolta ja päätyen luokkien välisiin riippuvaisuuksi...

  18. The Reliability and Maintainability Analysis of Pneumatic System of Rotary Drilling Machines

    Science.gov (United States)

    Rahimdel, Mohammad Javad; Hosienie, Seyed Hadi; Ataei, Mohammad; Khalokakaei, Reza

    2013-10-01

    In any blasthole drilling the bottom of the blasthole must be kept clean by evacuating drill cuttings or it flushing as soon as they appear to ensure efficient drilling. If it is not done well, a large quantity of energy will be consumed in regrinding with the consequent wear on drill bit and decrease penetration, apart from the risk of jamming. Therefore, research on reliability and probability of safe operation of pneumatic system of drilling machines is of prime importance to ensure safe drilling operations. In this paper, reliability of this system was modeled and analyzed. To doing this research, drilling machines in Sarcheshmeh Copper Mine in Iran have been selected for data collection and analysis. After reliability modeling of pneumatic system, maintenance scheduling has been presented based on different reliability levels. There were four rotary drilling machines in this mine (named A, B, C and D). Results showed that after about 7 h drilling of machines A and B, and after 103 and 44 h drilling of machines C and D respectively, noticeably the reliability of pneumatic system reached to 80 %. As a result, machines C and D have more reliable pneumatic systems in comparison to machines A and B and checking and servicing of pneumatic system before these time was essential. Also, maintainability analysis showed that more failures of pneumatic system of machines A, B, C and D will be noticeably repaired at about 28, 34, 6 and 9 h.

  19. The IAEA, nuclear power and sustainable development. Maintaining and increasing the overall assets available to future generations

    International Nuclear Information System (INIS)

    In the framework of one of the fundamental objectives of the IAEA mandate to enhance the contribution of nuclear technologies towards meeting the needs of Member States, the present status, all the aspects, and the future of nuclear power are reviewed. The development of nuclear power broadens the natural resource base usable for energy production, increases human and man-made capital, and when safely handled has little impact on ecosystems. This means that it could meet the central goal of sustainable development, considering that it covers maintaining or increasing the overall assets available to future generations, while minimizing consumption of finite resources and not exceeding the carrying capacities of ecosystems

  20. Favorable climatic regime for maintaining the present-day geometry of the Gregoriev Glacier, Inner Tien Shan

    OpenAIRE

    Fujita, K.; Takeuchi, N.; S.A. Nikitin; A. B. Surazakov; Okamoto, S; V. B. Aizen; Kubota, J.

    2011-01-01

    We conducted 2 yr (2005–2007) of in situ meteorological and glaciological observations on the Gregoriev Glacier, a flat-top glacier within the Inner Tien Shan, Kyrgyzstan. Relative carrier-phase GPS surveys reveal a vertical lowering at the summit of the glacier. Based on snow density data and an energy-mass balance model, we estimate that the annual precipitation and summer mean temperature required to maintain the glacier in the current state are 289 mm and −3.8 °C at the glacier summit (46...

  1. Nuclear power and sustainable development. Maintaining and increasing the overall assets available to future generations

    International Nuclear Information System (INIS)

    A central goal of sustainable development is to maintain or increase the overall assets available to future generations, while minimizing consumption of finite resources and not exceeding the carrying capacities of ecosystems. The development of nuclear power broadens the natural resource base usable for energy production, increases human and man-made capital, and, when safely handled, has little impact on ecosystems. Energy is essential for sustainable development. With continuing population and economic growth, and increasing needs in the developing world, substantially greater energy demand is a given, even taking into account continuing and accelerated energy efficiency and intensity improvements. Today, nuclear power is mostly utilized in industrialized countries that have the necessary technological, institutional and financial resources. Many of the industrialized countries that are able and willing to use nuclear power are also large energy consumers. Nuclear power currently generates 16% of the world's electricity. It produces virtually no sulfur dioxide, particulates, nitrogen oxides, volatile organic compounds or greenhouse gases. Globally, nuclear power currently avoids approximately 600 million tonnes of carbon emissions annually, about the same as hydropower. The 600 MtC avoided by nuclear power equals 8% of current global greenhouse gases emissions. In the OECD countries, nuclear power has for 35 years accounted for most of the reduction in the carbon intensity per unit of delivered energy. Existing operating nuclear power plants (NPPs) for which initial capital investments are largely depreciated are also often the most cost-effective way to reduce carbon emissions from electricity generation. In fact in the United States in 2000, NPPs were the most cost-effective way to generate electricity, irrespective of avoided carbon emissions. In other countries the advantages of existing nuclear generating stations are also increasingly recognized. Interest

  2. Energies; Energies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    In the framework of the National Debate on the energies in a context of a sustainable development some associations for the environment organized a debate on the nuclear interest facing the renewable energies. The first part presents the nuclear energy as a possible solution to fight against the greenhouse effect and the associated problem of the wastes management. The second part gives information on the solar energy and the possibilities of heat and electric power production. A presentation of the FEE (French wind power association) on the situation and the development of the wind power in France, is also provided. (A.L.B.)

  3. 27 CFR 31.163 - Requirements when a wholesale dealer in liquors maintains a retail department.

    Science.gov (United States)

    2010-04-01

    ... wholesale dealer in liquors maintains a retail department. 31.163 Section 31.163 Alcohol, Tobacco Products... wholesale dealer in liquors maintains a retail department. (a) Constructive receipt and sale. When a... spirits, and the retail sales of distilled spirits normally represent 90 percent or more of the volume...

  4. 43 CFR 2.5 - Does DOI maintain an index of its reading room materials?

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Does DOI maintain an index of its reading room materials? 2.5 Section 2.5 Public Lands: Interior Office of the Secretary of the Interior RECORDS... a FOIA Request § 2.5 Does DOI maintain an index of its reading room materials? Each bureau...

  5. Parental Choice of Schools in an Area Containing Grant-Maintained Schools.

    Science.gov (United States)

    Bradley, Howard

    1996-01-01

    Discusses a survey comparing parents' views of four British schools, two grant maintained (GM) and two local education authority (LEA) maintained. LEA school supporters believe these schools assess students more regularly and feature sound homework and uniform policies. GM school advocates believe their children will enjoy a pupil-centered…

  6. 36 CFR 1236.26 - What actions must agencies take to maintain electronic information systems?

    Science.gov (United States)

    2010-07-01

    ... for adding, changing, or deleting information in the system; and (7) Ensure the timely, authorized... take to maintain electronic information systems? 1236.26 Section 1236.26 Parks, Forests, and Public... electronic information systems? (a) Agencies must maintain inventories of electronic information systems...

  7. 20 CFR 200.5 - Protection of privacy of records maintained on individuals.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Protection of privacy of records maintained... ADMINISTRATION GENERAL ADMINISTRATION § 200.5 Protection of privacy of records maintained on individuals. (a... as his full name, date of birth, and social security number. The system manager shall respond to...

  8. 25 CFR 170.810 - To what standards must an IRR transportation facility be maintained?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false To what standards must an IRR transportation facility be maintained? 170.810 Section 170.810 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.810 To what standards must an IRR transportation facility be maintained?...

  9. Follower Reactions to Male and Female Leaders Who Maintain or Lose Reward Power.

    Science.gov (United States)

    Jurma, William E.; Wright, Beverly C.

    1990-01-01

    Investigated effects on group member satisfaction and communication behavior when male and female leaders either maintained or lost reward power during problem-solving sessions. Found group member communication was more substantive and positive when leaders maintained reward power than when they lost it; communication behavior was also affected by…

  10. Who Maintains/Relinquishes Which Language How and Why? A Response to Michael Clyne.

    Science.gov (United States)

    Wei, Li

    1997-01-01

    Response to an article on multiculturalism and the status of community languages in Australia, focusing on issues of language maintenance and shift emerging from the article and adding examples from other countries. Questions addressed include who is responsible for maintaining community languages, which are maintained, how this is done, and why,…

  11. Multi-Voxel Decoding and the Topography of Maintained Information During Visual Working Memory.

    Science.gov (United States)

    Lee, Sue-Hyun; Baker, Chris I

    2016-01-01

    The ability to maintain representations in the absence of external sensory stimulation, such as in working memory, is critical for guiding human behavior. Human functional brain imaging studies suggest that visual working memory can recruit a network of brain regions from visual to parietal to prefrontal cortex. In this review, we focus on the maintenance of representations during visual working memory and discuss factors determining the topography of those representations. In particular, we review recent studies employing multi-voxel pattern analysis (MVPA) that demonstrate decoding of the maintained content in visual cortex, providing support for a "sensory recruitment" model of visual working memory. However, there is some evidence that maintained content can also be decoded in areas outside of visual cortex, including parietal and frontal cortex. We suggest that the ability to maintain representations during working memory is a general property of cortex, not restricted to specific areas, and argue that it is important to consider the nature of the information that must be maintained. Such information-content is critically determined by the task and the recruitment of specific regions during visual working memory will be both task- and stimulus-dependent. Thus, the common finding of maintained information in visual, but not parietal or prefrontal, cortex may be more of a reflection of the need to maintain specific types of visual information and not of a privileged role of visual cortex in maintenance. PMID:26912997

  12. Large research infrastrucures and networking. Two key factors for maintaining nuclear expertise in Europe

    International Nuclear Information System (INIS)

    Large research infrastructures are of key importance to improve the efficiency and the safety of nuclear energy production. To support present and coming power reactors and fuel cycle facilities and to develop future systems, it is necessary to optimise these infrastructures and their use by taking into account the networking of existing facilities, the access by the European researchers to conduct their own research projects and the creation of new installations when facing ageing issues. Large infrastructures include material testing reactor, hot laboratories for material and fuel under irradiation studies, fuel cycle researches and facilities dedicated to severe accident studies. For example, the CEA severe accident study platform has been recently used by a Bulgarian team to conduct its own research project with a grant provided by the European Commission. Furthermore, because present European material testing reactors are ageing, renewing the irradiation capability is an important and structuring stake for the fission research in Europe in order to continue safe and optimised operations of existing reactors, to support Generation 4 RTD and to keep alive competences. Considering that, CEA has decided to launch the project Jules Horowitz aiming at building a new research reactor. The access to the CEA facilities, including the Jules Horowitz reactor, combined with equivalent possibilities of access to other European facilities through a specific platform would help to develop a long-term vision, to create a coherent and dynamic strategy, to contribute to the stimulation of a large cooperation on nuclear fission, to enable a common approach of safety issues, to gather competencies, to promote the attractiveness of nuclear research to young scientists and to maintain European nuclear expertise at the highest level. This paper intends to provide a view of the existing and needed infrastructures, discuss the ways of access and finally open the discussion on the

  13. Quantification of Libby Reservoir Levels Needed to Maintain or Enhance Reservoir Fisheries, 1985 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Chisholm, Ian

    1985-01-01

    The goal was to quantify seasonal water levels needed to maintain or enhance the reservoir fishery in Libby. This report summarizes data collected from July 1984 through July 1985, and, where appropriate, presents data collected since 1983. The Canada, Rexford, and Tenmile areas of the reservoir are differentially affected by drawdown. Relative changes in water volume and surface area are greatest in the Canada area and smallest in the Tenmile area. Reservoir morphology and hydraulics probably play a major role in fish distribution through their influence on water temperature. Greatest areas of habitat with optimum water temperature for Salmo spp. and kokanee occurred during the spring and fall months. Dissolved oxygen, pH and conductivity levels were not limiting during any sampling period. Habitat enhancement work was largely unsuccessful. Littoral zone vegetation plantings did not survive well, primarily the result of extreme water level fluctuations. Relative abundances of fish species varied seasonally within and between the three areas. Water temperature is thought to be the major influence in fish distribution patterns. Other factors, such as food availability and turbidity, may mitigate its influence. Sampling since 1975 illustrates a continued increase in kokanee numbers and a dramatic decline in redside shiners. Salmo spp., bull trout, and burbot abundances are relatively low while peamouth and coarsescale sucker numbers remain high. A thermal dynamics model and a trophic level components model will be used to quantify the impact of reservoir operation on the reservoir habitat, primary production, secondary production and fish populations. Particulate carbon will be used to track energy flow through trophic levels. A growth-driven population dynamics simulation model that will estimate the impacts of reservoir operation on fish population dynamics is also being considered.

  14. Maintaining the uranium resources data system and assessing the 1989 US uranium potential resources

    International Nuclear Information System (INIS)

    Under the Memorandum of Understanding (MOU) between the EIA, US Department of Energy, and the US Geological Survey (USGS), US Department of the Interior, the USGS develops estimates of uranium endowment for selected geological environments in the United States. New estimates of endowment are used to update the Uranium Resources Assessment Data (URAD) System which, beginning in 1990, is maintained for EIA by the USGS. For 1989, estimates of US undiscovered resources were generated using revised economic index values (current to December 1989) in the URAD system's cost model. The increase in the estimates for the Estimated Additional Resources (EAR) and Speculative Resources (SR) classes resulted primarily from increases in the estimates of uranium endowment for the solution-collapse, breccia-pipe uranium deposit environment in the Colorado Plateau resource region. The mean values for $30-, $50-, and $100-per-pound U3O8 forward-cost categories of EAR increased by about 8, 48, and 32 percent, respectively, as compared to 1988. Estimates of the 1989 undiscovered resources in the SR class also increased in all three forward-cost categories by 10, 5, and 9 percent, respectively. The original cost equations in the URAD System were designed to cover drilling costs related to extensive flat-lying tabular ore bodies. The equations do not adequately treat drilling costs for the smaller areas of vertical breccia pipe uranium deposits in the Colorado Plateau resource region. The development of appropriate cost equations for describing the economics of mining this type of deposit represents a major new task. 12 refs., 4 figs., 5 tabs

  15. A rationale for maintaining the double containment requirement for plutonium shipments

    Energy Technology Data Exchange (ETDEWEB)

    Channell, James K. [Environmental Evaluation Group, Albuquerque, NM (US); Anastas, George [Environmental Evaluation Group, Albuquerque, NM (US)

    2003-12-31

    Current U.S. Nuclear Regulatory Commission (NRC) transportation regulations (10 CFR 71.63 (b)) require that all shipments containing more than 20 curies of plutonium must be transported in packages that provide double containment. On April 30, 2002 the NRC issued a proposed rule that would eliminate §71.63(b) and the double containment requirement. NRC’s reasons for proposing elimination of §71.63(b) are: (1) compatibility with International Atomic Energy Agency Transportation Safety Standards (which do not have the requirement); (2) the current rule is inconsistent with the A1/A2 system since it applies only to plutonium; (3) double containment causes a heavier package and results in higher transportation costs; (4) the separate inner containment results in additional radiation exposure; and (5) while there would be additional protection from a separate inner container in an accident; this type of approach is not “risk informed nor performance based.” The Environmental Evaluation Group (EEG) has been a proponent of the double containment requirement for the Waste Isolation Pilot Plant (WIPP) shipments for twenty years. This requirement affects shipments to WIPP much more than any other current or planned shipping campaign because reactor fuel elements, metal or metal alloy, and vitrified high-level waste are exempt from §71.63(b). EEG submitted comments on the Proposed Rule on July 26, 2002 (Appendix C). This report is an update and expansion of the July 26, 2002 comments. Actual WIPP experience with shipments in the double contained TRUPACT-II package is used to respond to NRC arguments for deletion of §71.63(b) and offers a rationale for maintaining the current requirement.

  16. Developing maintainability for tokamak fusion power systems. Phase II report. Volume II: study results

    International Nuclear Information System (INIS)

    In this second phase the impact of unscheduled maintenance, several vacuum wall arrangements, and maintenance of other reactor interfacing subsystems and maintenance equipment are added to the evaluation of the maintainability of the fusion power reactor concepts. Four concepts are normalized to common performance parameters and evaluated for their capability to achieve availability and cost of electricity goals considering both scheduled and unscheduled maintenance. The results of this evaluation are used to generate a series of maintainability design guidelines and to select the more desirable features and design options which are used to configure a preliminary reactor concept having improved maintainability

  17. Troubleshooting and Maintaining Your PC All-in-One Desk Reference For Dummies

    CERN Document Server

    Gookin, Dan

    2009-01-01

    Maintaining a PC is important, and troubleshooting a PC can be a challenge. Dan Gookin is great at explaining how to handle common PC problems, and he's provided a complete, plain-English manual in Troubleshooting & Maintaining Your PC All-in-One For Dummies. Liberally laced with Dan's famous humor and clear instructions, Troubleshooting & Maintaining Your PC All-in-One For Dummies is divided into six minibooks covering hardware, software, laptops, Internet, networking, and maintenance. Each one gives you some background on what causes common problems, to help you understand what's wrong as we

  18. Nuclear energy research initiative (NERI)

    International Nuclear Information System (INIS)

    Objectives of the nuclear energy research initiative are: to address and help to overcome the principal technical and scientific obstacles to expand the use of nuclear energy in the US; advance the state of nuclear technology to maintain a competitive position in the overseas markets and a future domestic market; promote and maintain nuclear science and engineering; and to improve the performance, efficiency, reliability, economics and other attributes to enhance nuclear energy application

  19. Parcels and Land Ownership, Maintained by Dubuque County Assessor's Office, Published in 2007, City of Dubuque.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Parcels and Land Ownership dataset, was produced all or in part from Published Reports/Deeds information as of 2007. It is described as 'Maintained by Dubuque...

  20. Parking lots owned and maintained by the U.S. Fish and Wildlife Service

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — U.S. Fish and Wildlife Service parking lot inventory includes parking lots owned and maintained by the U.S. Fish and Wildlife Service on National Wildlife Refuges,...

  1. Molecular dynamics simulation study on zwitterionic structure to maintain the normal conformations of Glutathione

    Institute of Scientific and Technical Information of China (English)

    YAN; Han; ZHU; HaoMiao; SHEN; Jian

    2007-01-01

    Molecular dynamics simulations were applied to normal conformational Glutathione (GSH) and GSH over zwitterionic and hydrophobic surfaces respectively. Conformational analysis of GSH during the simulation time on RMSD, conformational flexibility and dihedral distribution were performed. The results showed that zwitterionic structure maintains the normal conformations of GSH to a better extent, which should be a first good proof of the hypothesis of "maintain of normal structure".

  2. Fixed functional space maintainer: novel aesthetic approach for missing maxillary primary anterior teeth

    OpenAIRE

    Khare, Vikram; Nayak, Prathibha Anand; Khandelwal, Vishal; Nayak, Ullal Anand

    2013-01-01

    The first-line treatment of non-restorable traumatically injured or carious deciduous teeth is extraction which may be a curse for the future dentition as well as social activity of a child. Various therapeutic modalities from removable partial dentures to fixed space maintainer can be used for replacement of such lost teeth. Two types of fixed aesthetic space maintainers for replacing premature loss of maxillary deciduous incisors in 4-year-old children are discussed.

  3. PTM Along Track Algorithm to Maintain Spacing During Same Direction Pair-Wise Trajectory Management Operations

    Science.gov (United States)

    Carreno, Victor A.

    2015-01-01

    Pair-wise Trajectory Management (PTM) is a cockpit based delegated responsibility separation standard. When an air traffic service provider gives a PTM clearance to an aircraft and the flight crew accepts the clearance, the flight crew will maintain spacing and separation from a designated aircraft. A PTM along track algorithm will receive state information from the designated aircraft and from the own ship to produce speed guidance for the flight crew to maintain spacing and separation

  4. Facilitating Consumer Clinical Information Seeking by Maintaining Referential Context: Evaluation of a Prototypic Approach

    OpenAIRE

    Lobach, David F.; Waters, Andrew; Silvey, Garry M.; Clark, Shelly J.; Kalyanaraman, Sri; Kawamoto, Kensaku; Lipkus, Isaac

    2009-01-01

    Millions of consumers seek health information on the Internet. Unfortunately, this searching often falls short because of design limitations of many consumer-oriented Web sites. In this paper, we describe an approach that addresses several known barriers to consumer health information seeking. This approach primarily involves maintaining the referential context throughout a consumer’s search for information. To maintain referential context, this approach uses multiple levels of hierarchical c...

  5. Maintaining Unity - Relatives in older patient's fast-track treatment programmes. A Grounded theory study

    DEFF Research Database (Denmark)

    Berthelsen, Connie Bøttcher; Lindhardt, Tove; Frederiksen, Kirsten

    2014-01-01

    over 70 years of age participated. The constant comparative method was the guiding principle for simultaneous data collection, data analysis and coding, while theoretically sampling and writing memos. FINDINGS: Maintaining Unity emerged as the relatives' pattern of behaviour through which they resolved...... to fit in with the patients' and health professionals' requirements. CONCLUSION: The substantive theory of Maintaining Unity offers knowledge of relatives' strong desire to provide compassionate and loving support for the older patients during fast-track treatment programmes....

  6. Employee turnover and maintaining knowledge continuity in large and small organisations

    OpenAIRE

    Linhartová, Lucie; Urbancová, Hana

    2011-01-01

    Determining the causes and consequences of employee turnover is necessary in order to maintain competitive advantage in today’s knowledge economy. For an organisation, an employee’s departure can mean the outflow of the knowledge that he or she possesses, and it is thus necessary to ensure its transfer in order to maintain knowledge continuity. The objective of the present article is to present the results of surveys on the causes of employee turnover and its perception by employers as possib...

  7. Foxp3+ regulatory T cells maintain immune homeostasis in the skin

    OpenAIRE

    DUDDA, Jan C.; Perdue, Nikole; Bachtanian, Eva; Campbell, Daniel J.

    2008-01-01

    Cutaneous immune responses must be tightly controlled to prevent unwanted inflammation in response to innocuous antigens, while maintaining the ability to combat skin-tropic pathogens. Foxp3+ regulatory T (T reg) cells are potent immune regulators and are found at high frequency in both human and mouse skin. Although T reg cells migrate to the skin and can dampen immune responses during experimentally induced inflammation or infection, the importance of cutaneous T reg cells for maintaining n...

  8. Evaluation of maintainability enhancement for TCP/TSP revision 6.0 update .20

    OpenAIRE

    Schneidewind, Norman Floyd

    1982-01-01

    ABSTRACT (Continue on reveree elde if neceeemry end Identity by block number) A system of documentation which was designed to aid programmers of the Command and Control System Maintenance Agency (CCSMA) in maintaining the Trident Command and Control System software was evaluated. This system is called "Maintainability Enhancement for TCP/TSP Revision 6.0 Update .20" or simply 6.0/. 20. It is essentially a hierarchical method of charting software procedures and the relationsh...

  9. An independent evaluation of the CH-46 safety reliability and maintainability program (SR&M)

    OpenAIRE

    Conklin, Michael J.

    1987-01-01

    This thesis is an independent partial evaluation of the Safety Reliability and Maintainability Program (SR&M). The two Measures of effectiveness which were used to see if the goals of this program were realized in the areas of maintainability and reliability are the Maintenance Manhours per Flight Hour and the Mean Flight Hours Between failures. Standard statistical analysis was performed utilizing the software packages GRAFSTAT and MINITAB.

  10. An Evaluation of Maintainability of Aspect-Oriented Systems: a Practical Approach

    OpenAIRE

    Avadhesh Kumar; Rajesh. Kumar; P. S. Grover

    2007-01-01

    Maintenance of software systems is becoming major concern for software developers and users. In software projects/products, where software changes/updates are frequently required to improve software quality, maintainability is an important characteristic of ISO 9126 quality standard to evaluate. Analyzability, changeability, stability, and testability are sub attributes/characteristics of maintainability in ISO 9126. In this paper, changeability is measured by making changes at code level of ...

  11. A Comparative Study of Biodegradation of Nickel and Chromium from Space Maintainers: An in vitro Study

    OpenAIRE

    Anand, Ashish; Sharma, Arun; Kumar, Piush; Sandhu, Meera; Sachdeva, Shobhit; Sachdev, Vinod

    2015-01-01

    ABSTRACT Objective: The aim of the study was to compare and evaluate the in vitro biodegradation of nickel and chromium from space maintainers, made of three different companies, i.e (Dantaurum, Rocky mountain and Dtech) in artificial saliva. Materials and methods: The study comprised of 30 space maintainers out of which 10 were fabricated using Dantaurum, 10 using Rocky mountain and 10 using Dtech band materials. Stainless steel wire (Dantaurum, Rocky mountain and Konark) was used for making...

  12. Identifying Regional Key Eco-Space to Maintain Ecological Security Using GIS

    OpenAIRE

    Hualin Xie; Guanrong Yao; Peng Wang

    2014-01-01

    Ecological security and environmental sustainability are the foundations of sustainable development. With the acceleration of urbanization, increasing human activities have promoted greater impacts on the eco-spaces that maintain ecological security. Regional key eco-space has become the primary need to maintain environmental sustainability and can offer society with continued ecosystem services. In this paper, considering the security of water resources, biodiversity conservation, disaster a...

  13. The linear system theory's account of behavior maintained by variable-ratio schedules.

    OpenAIRE

    McDowell, J. J; Wixted, J T

    1988-01-01

    The mathematical theory of linear systems, which has been used successfully to describe behavior maintained by variable-interval schedules, is extended to describe behavior maintained by variable-ratio schedules. The result of the analysis is a pair of equations, one of which expresses response rate on a variable-ratio schedule as a function of the mean ratio requirement (n) that the schedule arranges. The other equation expresses response rate on a variable-ratio schedule as a function of re...

  14. Assessing the Capability of Code Smells to Support Software Maintainability Assessments : Empirical Inquiry and Methodological Approach

    OpenAIRE

    2012-01-01

    Code smells are indicators of software design shortcomings that can decrease software maintainability. An advantage of code smells over traditional software measures is that the former are associated with an explicit set of refactoring strategies to improve the existing design. As such, code smell analysis is a promising approach to address both the assessment and the improvement of maintainability. An important challenge in code smell analysis is understanding the interplay between code smel...

  15. Role of the Criminal Law in Maintaining Hong Kong as an International Financial Centre

    OpenAIRE

    Young, SNM

    2015-01-01

    While criminal law is an essential part of the legal environment used to maintain Hong Kong’s status as an international financial centre (IFC), its role is limited. Criminal law and processes are reserved for serious cases that involve the protection of property rights, economic interests, or the integrity of the financial system. Deterrent and remedial civil processes are increasingly being used as a more effective way to enforce law designed to maintain Hong Kong’s IFC status.

  16. Moisture and dynamical interactions maintaining decoupled Arctic mixed-phase stratocumulus in the presence of a humidity inversion

    Directory of Open Access Journals (Sweden)

    A. Solomon

    2011-05-01

    Full Text Available Observations suggest that processes maintaining subtropical and Arctic stratocumulus differ, due to the different environments in which they occur. For example, specific humidity inversions (specific humidity increasing with height are frequently observed to occur coincident with temperature inversions in the Arctic, while they do not occur in the subtropics. In this study we use nested LES simulations of decoupled Arctic Mixed-Phase Stratocumulus (AMPS clouds observed during the DOE Atmospheric Radiation Measurement Program's Indirect and SemiDirect Aerosol Campaign (ISDAC to analyze budgets of water components, potential temperature, and turbulent kinetic energy. These analyses quantify the processes that maintain decoupled AMPS, including the role of the humidity inversions. The results show the maintenance of liquid clouds in both the shallow upper entrainment zone (temperature and humidity inversion due to a down gradient transport of water vapor by turbulent fluxes into the cloud layer and direct condensation by radiative cooling, and in the updrafts of the mixed-layer eddies below cloud top due to buoyant destabilization. These processes cause at least 20 % of the cloud liquid water to extend into the inversion. The redistribution of water vapor from the top of the humidity inversion to the base of the humidity inversion maintains the cloud layer while the mixed layer-entrainment zone system is continually losing total water. In this decoupled system, the humidity inversion is the only source of water vapor for the cloud system since water vapor from the surface layer is not efficiently transported into the mixed layer. Sedimentation of ice is the dominant sink of moisture from the mixed layer.

  17. A whole-body model for glycogen regulation reveals a critical role for substrate cycling in maintaining blood glucose homeostasis.

    Directory of Open Access Journals (Sweden)

    Ke Xu

    2011-12-01

    Full Text Available Timely, and sometimes rapid, metabolic adaptation to changes in food supply is critical for survival as an organism moves from the fasted to the fed state, and vice versa. These transitions necessitate major metabolic changes to maintain energy homeostasis as the source of blood glucose moves away from ingested carbohydrates, through hepatic glycogen stores, towards gluconeogenesis. The integration of hepatic glycogen regulation with extra-hepatic energetics is a key aspect of these adaptive mechanisms. Here we use computational modeling to explore hepatic glycogen regulation under fed and fasting conditions in the context of a whole-body model. The model was validated against previous experimental results concerning glycogen phosphorylase a (active and glycogen synthase a dynamics. The model qualitatively reproduced physiological changes that occur during transition from the fed to the fasted state. Analysis of the model reveals a critical role for the inhibition of glycogen synthase phosphatase by glycogen phosphorylase a. This negative regulation leads to high levels of glycogen synthase activity during fasting conditions, which in turn increases substrate (futile cycling, priming the system for a rapid response once an external source of glucose is restored. This work demonstrates that a mechanistic understanding of the design principles used by metabolic control circuits to maintain homeostasis can benefit from the incorporation of mathematical descriptions of these networks into "whole-body" contextual models that mimic in vivo conditions.

  18. Moisture and dynamical interactions maintaining decoupled Arctic mixed-phase stratocumulus in the presence of a humidity inversion

    Directory of Open Access Journals (Sweden)

    A. Solomon

    2011-10-01

    Full Text Available Observations suggest that processes maintaining subtropical and Arctic stratocumulus differ, due to the different environments in which they occur. For example, specific humidity inversions (specific humidity increasing with height are frequently observed to occur near cloud top coincident with temperature inversions in the Arctic, while they do not occur in the subtropics. In this study we use nested LES simulations of decoupled Arctic Mixed-Phase Stratocumulus (AMPS clouds observed during the DOE Atmospheric Radiation Measurement Program's Indirect and SemiDirect Aerosol Campaign (ISDAC to analyze budgets of water components, potential temperature, and turbulent kinetic energy. These analyses quantify the processes that maintain decoupled AMPS, including the role of humidity inversions. Key structural features include a shallow upper entrainment zone at cloud top that is located within the temperature and humidity inversions, a mixed layer driven by cloud-top cooling that extends from the base of the upper entrainment zone to below cloud base, and a lower entrainment zone at the base of the mixed layer. The surface layer below the lower entrainment zone is decoupled from the cloud mixed-layer system. Budget results show that cloud liquid water is maintained in the upper entrainment zone near cloud top (within a temperature and humidity inversion due to a down gradient transport of water vapor by turbulent fluxes into the cloud layer from above and direct condensation forced by radiative cooling. Liquid water is generated in the updraft portions of the mixed-layer eddies below cloud top by buoyant destabilization. These processes cause at least 20% of the cloud liquid water to extend into the inversion. The redistribution of water vapor from the top of the humidity inversion to its base maintains the cloud layer, while the mixed layer-entrainment zone system is continually losing total water. In this decoupled system, the humidity inversion is

  19. Five-year summary report of an experimental dairy herd maintained on the Nevada Test Site 1971--1975

    International Nuclear Information System (INIS)

    The Environmental Monitoring and Support Laboratory-Las Vegas, U.S. Environmental Protection Agency, maintains an experimental dairy herd in Area 15 of the U.S. Energy Research and Development Administration's Nevada Test Site. This report covers the period January 1, 1971, through December 31, 1975, giving the status of the herd for this period of time. Improvements, changes, and additions made on the facilities, the production and reproduction statistics of individual cows and the herd, and summaries of metabolism studies that involved the dairy herd are also covered in this report. Data are included from studies on the tissue distribution of tracer doses of 238Pu and /sup 129m/Tl in selected cattle

  20. THE SHALE SOLUTION -How the Economic Growth Shale Gas Production in Pennsylvania has Contributed to can be Maintained, Even After the Gas is Depleted.

    OpenAIRE

    Akselsen, Anniken Berg

    2014-01-01

    The emergence of hydrocarbon energy extracted from shale has been nicknamed the Shale Gas Revolution , due to its implications for the American society, geo-politics and economy. This thesis will explain how the economic growth shale gas production in Pennsylvania so far has contributed to can be maintained, also for the future, when shale gas is no longer produced or depleted. By focusing on Pennsylvania, which has the nation s highest shale gas production growth rate, this thesis will exam...

  1. Recommendations to the NRC on human engineering guidelines for nuclear power plant maintainability

    Energy Technology Data Exchange (ETDEWEB)

    Badalamente, R.V.; Fecht, B.A.; Blahnik, D.E.; Eklund, J.D.; Hartley, C.S.

    1986-03-01

    This document contains human engineering guidelines which can enhance the maintainability of nuclear power plants. The guidelines have been derived from general human engineering design principles, criteria, and data. The guidelines may be applied to existing plants as well as to plants under construction. They apply to nuclear power plant systems, equipment and facilities, as well as to maintenance tools and equipment. The guidelines are grouped into seven categories: accessibility and workspace, physical environment, loads and forces, maintenance facilities, maintenance tools and equipment, operating equipment design, and information needs. Each chapter of the document details specific maintainability problems encountered at nuclear power plants, the safety impact of these problems, and the specific maintainability design guidelines whose application can serve to avoid these problems in new or existing plants.

  2. Recommendations to the NRC on human engineering guidelines for nuclear power plant maintainability

    International Nuclear Information System (INIS)

    This document contains human engineering guidelines which can enhance the maintainability of nuclear power plants. The guidelines have been derived from general human engineering design principles, criteria, and data. The guidelines may be applied to existing plants as well as to plants under construction. They apply to nuclear power plant systems, equipment and facilities, as well as to maintenance tools and equipment. The guidelines are grouped into seven categories: accessibility and workspace, physical environment, loads and forces, maintenance facilities, maintenance tools and equipment, operating equipment design, and information needs. Each chapter of the document details specific maintainability problems encountered at nuclear power plants, the safety impact of these problems, and the specific maintainability design guidelines whose application can serve to avoid these problems in new or existing plants

  3. The business case: collaborating to help employees maintain their mental well-being.

    Science.gov (United States)

    Sairanen, Sari; Matzanke, Deanna; Smeall, Doug

    2011-01-01

    There has been a change in the mindset of businesses in recent years. Companies are starting to realize that proactively helping their employees to maintain mental health is beneficial, both for their workers and their business. In this article, we present three different but complementary views - those of an advocate, an employer and a provider - on helping employees maintain mental, and physical, health. In the first section, Sari Sairanen outlines programs and services to manage stress and maintain mental health that have been developed by the Canadian Auto Workers' union and implemented in partnership with employers, wellness providers, service agencies and other community partners. The union focuses on raising awareness and providing education, as well as removing the stigma associated with mental illness. Deanna Matzanke, in her section, discusses the commitment of a company, Scotiabank, to create and maintain an inclusive and accessible workplace for all its employees. It has recently worked with providers to develop and implement integrated services dealing specifically with mental health illness and addiction, which aid not only its current employees but also possible future employees. Finally, Doug Smeall shares his observations as an insurer at Sun Life Financial, who has seen the rates of both short-term and long-term disabilities increase. He elaborates on the collaborative work between insurers and employers to help employees maintain their mental health, and to return to work sooner when issues do occur. Ultimately, this article argues that unions, employers and insurers can work together with partners and employees to promote and maintain employee health because, as Sairanen asserts, "preventing a problem in the first place is the best strategy." PMID:24917259

  4. Kekuatan Geser dan Pola Patahan Loop Space Maintainer yang Dibuat dengan Teknik Spot Welding Elektrik

    Directory of Open Access Journals (Sweden)

    Elin Karlina

    2015-10-01

    Full Text Available The aim of this research was to study the effect of spot variations on shear strength of spot welds in an electric loop space maintainer. Stainless steel wire of 0.8 mm diameter and nickel chromium crwon for lower second molar of temporary teeth were used. A loop 1 cm wide, made of 3.5 cm stainless steel wire, was welded with 3 dots on the crown using an electric spot welder. Each dot for each group took different spot variations from 1 X – 4 X. A loop space maintainer made with the usual materials and techniques as applied at the IKGA FKG UI Clinic was used as a control, with a torch as heat source. Ten specimens each were prepared for shear testing and three spesimens each for metallography. Universal testing machine was used for shear strength testing at a crosshead speed of 0.5 mm/min, and SEM/EDS was used for metallography and fractography. The data were statistically analyzed with one-way ANOVA at p = 0.05, and Tukey post hoc test. The results show that the shear strength of the welded loop space maintainer was higher than that of a soldered loop space maintainer, although the difference was not statistically significant with spot variation 1 X. SEM/EDS analysis suggests that a new alloy forms at the contact area of welded and soldered loop space maintainer. Fractography of the joints suggests that welds are better than soldered joints, with higher ductility and toughness, as can be seen from the dimpled pattern of the welded joint and cleavage patterns in the control joints. In conclusion, the loop space maintainer is better made by welding than by soldering.

  5. Why practice yoga? Practitioners' motivations for adopting and maintaining yoga practice.

    Science.gov (United States)

    Park, Crystal L; Riley, Kristen E; Bedesin, Elena; Stewart, V Michelle

    2016-06-01

    We examined motives for adopting and maintaining yoga practice in a national survey of yoga practitioners (360 yoga students, 156 yoga teachers). Both students and teachers adopted yoga practice primarily for exercise and stress relief, but reported many other reasons, including flexibility, getting into shape, and depression/anxiety relief. Over 62 percent of students and 85 percent of teachers reported having changed their primary reason for practicing or discovering other reasons; for both, the top changed primary reason was spirituality. Findings suggest that most initiate yoga practice for exercise and stress relief, but for many, spirituality becomes their primary reason for maintaining practice. PMID:25030795

  6. Systems and methods for maintaining multiple objects within a camera field-of-view

    Science.gov (United States)

    Gans, Nicholas R.; Dixon, Warren

    2016-03-15

    In one embodiment, a system and method for maintaining objects within a camera field of view include identifying constraints to be enforced, each constraint relating to an attribute of the viewed objects, identifying a priority rank for the constraints such that more important constraints have a higher priority that less important constraints, and determining the set of solutions that satisfy the constraints relative to the order of their priority rank such that solutions that satisfy lower ranking constraints are only considered viable if they also satisfy any higher ranking constraints, each solution providing an indication as to how to control the camera to maintain the objects within the camera field of view.

  7. Interleukin 17A controls Interleukin 17F production and maintains blood neutrophil counts in mice

    OpenAIRE

    von Vietinghoff, Sibylle; Ley, Klaus

    2009-01-01

    Granulocyte colony-stimulating factor (G-CSF), its receptor and interleukin-17 receptor A (IL-17RA) are all required to maintain baseline neutrophil counts in mice. Here, we tested whether IL-17F could compensate and maintain baseline neutrophil counts in the absence of IL-17A. Unlike the reduced neutrophil counts found in IL-17RA deficient mice, neutrophil counts were mildly increased in IL-17A deficient (Il17a-/-) animals. There was no evidence for infection or altered neutrophil function. ...

  8. A simple and effective way of maintaining the microvascular field clean and dry during anastomosis

    Directory of Open Access Journals (Sweden)

    G I Nambi

    2013-01-01

    Full Text Available During microvascular anastomosis, it is important to maintain the microsurgical field irrigated yet dry so as to achieve a good view of the vessels for approximation. In this method, an infant feeding tube (size 4, with its tip sandwiched between layers of dry gauze and a surgical glove component placed in the anastomotic field and the other end connected to a suction apparatus, is used to maintain the microsurgical field free from flooding. It also has the additional advantage of providing a stable platform for microvascular anastomosis.

  9. Licensee programs for maintaining occupational exposure to radiation as low as is reasonably achievable

    International Nuclear Information System (INIS)

    This report defines the concept of maintaining occupational exposures to radiation as low as is reasonably achievable (ALARA) and describes the elements necessary for specific licensees to implement, operate, and evaluate an effective ALARA program. Examples of cost-effectiveness analysis and optimization are provided. The rationale for providing more detailed guidance to specific licensees stems from the current recommendations provided by the International Commission on Radiological Protection, as well as from the increased regulatory emphasis on maintaining occupational exposures ALARA. The objective of this work is to provide the Nuclear Regulatory Commission with a basis for updating Regulatory Guide 8.10

  10. Kekuatan Geser dan Pola Patahan Loop Space Maintainer yang Dibuat dengan Teknik Spot Welding Elektrik

    OpenAIRE

    Elin Karlina; Ellyza Herda; Heriandi Sutadi

    2015-01-01

    The aim of this research was to study the effect of spot variations on shear strength of spot welds in an electric loop space maintainer. Stainless steel wire of 0.8 mm diameter and nickel chromium crwon for lower second molar of temporary teeth were used. A loop 1 cm wide, made of 3.5 cm stainless steel wire, was welded with 3 dots on the crown using an electric spot welder. Each dot for each group took different spot variations from 1 X – 4 X. A loop space maintainer made with the usual mat...

  11. The micro and the macro: How discourse of control maintains HIV-related stigma.

    Science.gov (United States)

    Ranjbar, Vania; McKinlay, Andy; McVittie, Chris

    2016-02-01

    In this article, we examine how HIV/AIDS caregivers negotiate stigma in their discourse of providing care to HIV-positive individuals. Using interview data, we demonstrate how participants employed discourse of control in attempting to avoid and counter HIV-related stigma: participants rejected fear of associating with HIV-positive individuals by drawing on their knowledge of HIV transmission and their ability to control and avoid infection. Such discourses backfire, however, as the concept of HIV infection being controllable and thus avoidable maintains accountability for the disease. Thus, participants' micro discourse of control can maintain the macro discourse that produces HIV-related stigma. PMID:24648322

  12. Hale and Hearty Policies: How Psychological Science Can Create and Maintain Healthy Habits.

    Science.gov (United States)

    Rothman, Alexander J; Gollwitzer, Peter M; Grant, Adam M; Neal, David T; Sheeran, Paschal; Wood, Wendy

    2015-11-01

    Strategies are needed to ensure that the U.S. Government meets its goals for improving the health of the nation (e.g., Healthy People 2020). To date, progress toward these goals has been undermined by a set of discernible challenges: People lack sufficient motivation, they frequently fail to translate healthy intentions into action, their efforts are undermined by the persistence of prior unhealthy habits, and they have considerable difficulty maintaining new healthy patterns of behavior. Guided by advances in psychological science, we provide innovative, evidence-based policies that address each of these challenges and, if implemented, will enhance people's ability to create and maintain healthy behavioral practices. PMID:26581721

  13. Sharing the sandbox: Evolutionary mechanisms that maintain bacterial cooperation [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Eric Bruger

    2015-12-01

    Full Text Available Microbes are now known to participate in an extensive repertoire of cooperative behaviors such as biofilm formation, production of extracellular public-goods, group motility, and higher-ordered multicellular structures. A fundamental question is how these cooperative tasks are maintained in the face of non-cooperating defector cells. Recently, a number of molecular mechanisms including facultative participation, spatial sorting, and policing have been discovered to stabilize cooperation. Often these different mechanisms work in concert to reinforce cooperation. In this review, we describe bacterial cooperation and the current understanding of the molecular mechanisms that maintain it.

  14. Maintaining a Technology-Neutral Approach to Hydrogen Production Process Development through Conceptual Design of the Next Generation Nuclear Plant

    International Nuclear Information System (INIS)

    The Next Generation Nuclear Plant (NGNP) project was authorized in the Energy Policy Act of 2005 (EPAct), tasking the U.S. Department of Energy (DOE) with demonstrating High Temperature Gas-Cooled Reactor (HTGR) technology. The demonstration is to include the technical, licensing, operational, and commercial viability of HTGR technology for the production of electricity and hydrogen. The Nuclear Hydrogen Initiative (NHI), a component of the DOE Hydrogen Program managed by the Office of Nuclear Energy, is also investigating multiple approaches to cost effective hydrogen production from nuclear energy. The objective of NHI is development of the technology and information basis for a future decision on commercial viability. The initiatives are clearly intertwined. While the objectives of NGNP and NHI are generally consistent, NGNP has progressed to the project definition phase and the project plan has matured. Multiple process applications for the NGNP require process heat, electricity and hydrogen in varied combinations and sizes. Coupling these processes to the reactor in multiple configurations adds complexity to the design, licensing and demonstration of both the reactor and the hydrogen production process. Commercial viability of hydrogen production may depend on the specific application and heat transport configuration. A component test facility (CTF) is planned by the NGNP to support testing and demonstration of NGNP systems, including those for hydrogen production, in multiple configurations. Engineering-scale demonstrations in the CTF are expected to start in 2012 to support scheduled design and licensing activities leading to subsequent construction and operation. Engineering-scale demonstrations planned by NHI are expected to start at least two years later. Reconciliation of these schedules is recommended to successfully complete both initiatives. Hence, closer and earlier integration of hydrogen process development and heat transport systems is sensible

  15. Pacific Northwest Laboratory plan to maintain radiation exposure as low as reasonably achievable (ALARA)

    International Nuclear Information System (INIS)

    This document describes the radiation safety program at the Pacific Northwest Laboratory (PNL). The practices and administrative policies of this program support the principles of ALARA (to maintain radiation exposure as low as reasonably achievable). This document also describes a program to establish safety goals at PNL to help ensure that operations are conducted according to ALARA principles

  16. Canada must keep single-tier health care, National Forum on Health maintains

    OpenAIRE

    Rafuse, Jill

    1995-01-01

    As new knowledge and economic constraints affect the delivery of health care services, Canada is embarking on a reassessment of its medicare program. Even before the dialogue gets under way, however, the National Forum on Health that was appointed by the prime minister has already taken one firm stand by declaring that Canada must maintain its single-tier health care system.

  17. Beaver dams maintain fish biodiversity by increasing habitat heterogeneity throughout a low-gradient stream network

    Science.gov (United States)

    Smith, Joseph M.; Mather, Martha E.

    2013-01-01

    Understanding the relationship between heterogeneity and biodiversity is an active focus of ecological research. Although habitat heterogeneity is conceptually linked to biodiversity, the amount and configuration of heterogeneity that maintains biodiversity within ecosystems is not well understood, especially for an entire stream network.

  18. Factors Associated with Young Children's Opportunities for Maintaining Family Relationships during Maternal Incarceration

    Science.gov (United States)

    Poehlmann, Julie; Shlafer, Rebecca J.; Maes, Elizabeth; Hanneman, Ashley

    2008-01-01

    Children affected by maternal incarceration experience challenges maintaining continuous family relationships because of changes in caregivers, separation from siblings, and limited contact with mothers. In this mixed-method study, we investigated maternal and contextual factors associated with continuity in family relationships of children living…

  19. Metabolic and hemodynamic effects of saline infusion to maintain volemia on temporary abdominal aortic occlusion

    Directory of Open Access Journals (Sweden)

    Fábio Ferreira Amorim

    2002-10-01

    Full Text Available OBJECTIVE: To analyze hemodynamic and metabolic effects of saline solution infusion in the maintenance of blood volume in ischemia-reperfusion syndrome during temporary abdominal aortic occlusion in dogs. METHODS: We studied 20 dogs divided into 2 groups: the ischemia-reperfusion group (IRG, n=10 and the ischemia-reperfusion group with saline solution infusion aiming at maintaining mean pulmonary arterial wedge pressure between 10 and 20 mmHg (IRG-SS, n=10. All animals were anesthetized with sodium thiopental and maintained on spontaneous ventilation. Occlusion of the supraceliac aorta was obtained with inflation of a Fogarty catheter inserted through the femoral artery. After 60 minutes of ischemia, the balloon was deflated, and the animals were observed for another 60 minutes of reperfusion. RESULTS: IRG-SS dogs did not have hemodynamic instability after aortic unclamping, and the mean systemic blood pressure and heart rate were maintained. However, acidosis worsened, which was documented by a greater reduction of arterial pH that occurred especially due to the absence of a respiratory response to metabolic acidosis that was greater with the adoption of this procedure. CONCLUSION: Saline solution infusion to maintain blood volume avoided hemodynamic instability after aortic unclamping. This procedure, however, caused worsening in metabolic acidosis in this experimental model.

  20. Digital Avionics Information System (DAIS): Reliability and Maintainability Model. Final Report.

    Science.gov (United States)

    Czuchry, Andrew J.; And Others

    The reliability and maintainability (R&M) model described in this report represents an important portion of a larger effort called the Digital Avionics Information System (DAIS) Life Cycle Cost (LCC) Study. The R&M model is the first of three models that comprise a modeling system for use in LCC analysis of avionics systems. The total system will…

  1. The Role of a Grandmother in Maintaining Bangla with Her Granddaughter in East London

    Science.gov (United States)

    Ruby, Mahera

    2012-01-01

    First-generation Bangladeshi grandparents in the UK have consciously taken on the role of maintaining the linguistic and cultural identity of their grandchildren. Through their life experiences, they have built up "funds of knowledge" and skills that they are able to use to promote learning using strategies that are personalised and effective in…

  2. Male sterility of triticale lines generated through recombination of triticale and rye maintainers

    Directory of Open Access Journals (Sweden)

    Tomasz Warzecha

    2014-11-01

    Full Text Available The Triticum timopheevi cytoplasmic male sterility (cms system in triticale (xTriticosecale Wittmack suffers from a low frequency of maintainers and environmental instability of the male sterility. On the other hand, the Pampa cms system in rye (Secale cereale exhibits strong male sterility and a low frequency of restorers. Here, we report generating hybrids between maintainers of the T. timopheevi cms system in triticale and maintainers of the rye Pampa cms system. Ten hybrids were obtained. Their hybridity was verified by PCR (polymerase chain reaction using ISSR (inter simple sequence repeats primers. The cms maintaining ability of F2 individuals and their progeny was tested. The F2 plants were crossed to male sterile lines of triticale carrying the T. timopheevi cytoplasm. Among 180 G1 offspring of these crosses, 71 (39.4% were completely male sterile. Fourteen F2 individuals (7.8%, as well as their F2S1 and progeny, generated stable male sterility in G1, G1BC1 and G1BC2 generations after the crosses. Our results suggest that it is possible to produce a more stable cms system in triticale based on the T. timopheevi cytoplasm as compared to the existing one.

  3. 76 FR 51041 - Hemoglobin Standards and Maintaining Adequate Iron Stores in Blood Donors; Public Workshop

    Science.gov (United States)

    2011-08-17

    ... HUMAN SERVICES Food and Drug Administration Hemoglobin Standards and Maintaining Adequate Iron Stores in... workshop. The Food and Drug Administration (FDA) is announcing a public workshop entitled: ``Hemoglobin... discuss blood donor hemoglobin and hematocrit qualification standards in the United States, its impact...

  4. Emergo : a tool for improving maintainability of preprocessor-based product lines

    DEFF Research Database (Denmark)

    Ribeiro, Márcio; Tolêdo, Társis; Winther, Johnni;

    2012-01-01

    information about other features that can be impacted during a maintenance task. In this paper, we present Emergo, a tool capable of computing emergent interfaces between the feature we are maintaining and the others. Emergo relies on feature-sensitive dataflow analyses in the sense it takes features and the...

  5. What Does Value Mean and How is it Created, Maintained and Destroyed?

    OpenAIRE

    Bowman, Cliff; Ambrosini, Veronique

    2003-01-01

    In this paper we suggest that 'value' has a different meaning for different stakeholders and that if the firm operates in line with investor interests, it acts as both customer and supplier and its motivations will reflect these roles. We then consider internal activities that reflect these motivations. Other activities maintain the firm, and some destroy value. Implications for the RBV are explored.

  6. Does weeping lovegrass maintain its crude protein content at the expense of its neighbors?

    Science.gov (United States)

    Data would suggest that weeping lovegrass [Eragrostis curvula (Schrad.) Nees] does maintain its crude protein (CP) content at a steady state at the expense of its surrounding neighbors. While studying the combining ability effects of binary mixtures of cool- and warm-season grasses and legumes it w...

  7. Evaluation of antibiotic releasing porous polymethylmethacrylate space maintainers in an infected composite tissue defect model

    NARCIS (Netherlands)

    Spicer, P.P.; Shah, S.R.; Henslee, A.M.; Watson, B.M.; Kinard, L.A.; Kretlow, J.D.; Bevil, K.; Kattchee, L.; Bennett, G.N.; Demian, N.; Mende, K.; Murray, C.K.; Jansen, J.A.; Wong, M.E.; Mikos, A.G.; Kasper, F.K.

    2013-01-01

    This study evaluated the in vitro and in vivo performance of antibiotic-releasing porous polymethylmethacrylate (PMMA)-based space maintainers comprising a gelatin hydrogel porogen and a poly(dl-lactic-co-glycolic acid) (PLGA) particulate carrier for antibiotic delivery. Colistin was released in vit

  8. Maintaining Work: The Influence of Child Care Subsidies on Child Care-Related Work Disruptions

    Science.gov (United States)

    Forry, Nicole D.; Hofferth, Sandra L.

    2011-01-01

    With the passage of welfare reform, support for low-income parents to not only obtain but also maintain work has become imperative. The role of child care subsidies in supporting parents' job tenure has received little attention in the literature. This article examines the association between receiving a child care subsidy and experiencing a child…

  9. 5 CFR 1630.3 - Publication of systems of records maintained.

    Science.gov (United States)

    2010-01-01

    ... maintained. 1630.3 Section 1630.3 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD PRIVACY... or revision of a system of records, the Board will publish in the Federal Register notice of any new... revised, the Board will publish in the Federal Register a notice about the system. The notice...

  10. Family Financial Management Program at Virginia Tech Maintains Registration by CFP•À_•À_ Board

    OpenAIRE

    Elliott, Jean

    2004-01-01

    Virginia Tech's Family Financial Management program has maintained it's registration with the Certified Financial Planner Board of Standards Inc. (CFP Board) through January 2009. The Virginia Tech undergraduate degree program, which prepares students to enter careers in financial planning, was first accredited in 1997.

  11. Presenting the Self: An Interactive Approach to Teaching Interpersonal Awareness and Maintaining Face

    Science.gov (United States)

    George, Ashley Joiner

    2013-01-01

    This article describes an activity whose objective is for students to gain self-awareness related to the ways in which humans (consciously or not) alter their self-presentation depending upon the context, thereby maintaining different "faces." Also, this activity aims to highlight effectiveness related to different modes of nonverbal…

  12. Work-Life Balance: Strategies for Attaining and Maintaining Work-Life Balance

    Science.gov (United States)

    Winkler, Josette Chinchiolo

    2010-01-01

    Purpose: It was the purpose of this study (a) to identify and describe the elements of balance that elementary principals perceive as most important to their personal and professional lives; (b) to identify the strategies elementary principals perceive as most important to maintain balance in their personal and professional lives; (c) to determine…

  13. Tractor Mechanics: Maintaining and Servicing the Fuel System. Learning Activity Packages 20-33.

    Science.gov (United States)

    Clemson Univ., SC. Vocational Education Media Center.

    Learning activity packages are presented for instruction in tractor mechanics. The packages deal with the duties involved in maintaining the fuel system. The following fourteen learning activity packages are included: servicing fuel and air filters, servicing fuel tanks and lines, adjusting a carburetor, servicing a carburetor, servicing the…

  14. Furloughs and Faculty Management of Time: Maintaining Quality in an Economic Crisis

    Science.gov (United States)

    Jones, Loring; Hohman, Melinda; Mathiesen, Sally; Finnegan, Daniel

    2014-01-01

    An anonymous Web-based survey was used to gather the perceptions and experiences from 114 faculty members teaching in 16 social work programs in the California State University system about the effect of severe budget cuts on their educational activities. Most respondents reported they worked on their furlough days and maintained the same or…

  15. 41 CFR 102-74.180 - What illumination levels must Federal agencies maintain on Federal facilities?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What illumination levels must Federal agencies maintain on Federal facilities? 102-74.180 Section 102-74.180 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY...

  16. 33 CFR 154.1041 - Specific response information to be maintained on mobile MTR facilities.

    Science.gov (United States)

    2010-07-01

    ... maintained on mobile MTR facilities. (a) Each mobile MTR facility must carry the following information as... respond to a discharge from the mobile MTR facility. (3) List of the appropriate persons and agencies... National Response Center. (b) The owner or operator of the mobile facility must also retain the...

  17. Young Children with a Positive Reputation to Maintain Are Less Likely to Cheat

    Science.gov (United States)

    Fu, Genyue; Heyman, Gail D.; Qian, Miao; Guo, Tengfei; Lee, Kang

    2016-01-01

    The present study examined whether having a positive reputation to maintain makes young children less likely to cheat. Cheating was assessed through a temptation resistance paradigm in which participants were instructed not to cheat in a guessing game. Across three studies (total N = 361), preschool-aged participants were randomly assigned to…

  18. Semi-reciprocal polarization maintaining fibre coupler with distinctive transmission characteristics

    Science.gov (United States)

    Wang, Xinyue; Thomas, Freya; Wang, Ziyu

    2015-11-01

    Optical couplers are very important devices in optical communication systems and optical sensor systems. Several types of optical couplers with different materials or different transmission characteristics have been reported. Here we propose a semi-reciprocal polarization maintaining fibre coupler with unique transmission characteristics, which is distinct from conventional polarization maintaining fibre couplers and polarization beam splitters, and investigate the characteristics of the coupler theoretically and experimentally. The experimental results show that for circularly and elliptically polarized input light, the proposed coupler will act both as an in-line polariser and a conventional polarization maintaining fibre coupler. The output polarization extinction ratio of the transmission arm is 31.79 dB at a centre wavelength of 841 nm. For linearly polarized input light, the coupler will merely act as a conventional 3 dB polarization maintaining fibre coupler. The unique features of the proposed coupler enables the removal of polarisers from optical sensor systems and coherent optical communication systems, and reduces the insertion loss and production cost of the optical path. Therefore there is wide application for this device in optical sensor systems and optical communication systems.

  19. Performance of Polarizers and Coupler in an All Polarization Maintaining Fiber Interferometer

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhe; LIAO Yanbiao; HU Yongrning; LI Xiujian; MENG Zhou

    2000-01-01

    It is given mathematical models and analyze the performance of polarizers and coupler in an all polarization maintaining fiber (PMF) Michelson interferometer. The optical coherent signal to noise ratio (CSNR) of the interferometer is calculated by means of the Jones matrix with cross coupling matrix elements.

  20. Standard methods for maintaining adult Apis mellifera in cages under in vitro laboratory conditions

    NARCIS (Netherlands)

    Williams, G.R.; Alaux, C.; Costa, C.; Csaki, C.; Steen, van der J.J.M.

    2013-01-01

    Adult honey bees are maintained in vitro in laboratory cages for a variety of purposes. For example, researchers may wish to perform experiments on honey bees caged individually or in groups to study aspects of parasitology, toxicology, or physiology under highly controlled conditions, or they may c

  1. Configuration maintaining control of three-body ring tethered system based on thrust compensation

    Science.gov (United States)

    Huang, Panfeng; Liu, Binbin; Zhang, Fan

    2016-06-01

    Space multi-tethered systems have shown broad prospects in remote observation missions. This paper mainly focuses on the dynamics and configuration maintaining control of space spinning three-body ring tethered system for such mission. Firstly, we establish the spinning dynamic model of the three-body ring tethered system considering the elasticity of the tether using Newton-Euler method, and then validate the suitability of this model by numerical simulation. Subsequently, LP (Likins-Pringle) initial equilibrium conditions for the tethered system are derived based on rigid body's equilibrium theory. Simulation results show that tether slack, snapping and interaction between the tethers exist in the three-body ring system, and its' configuration can not be maintained without control. Finally, a control strategy based on thrust compensation, namely thrust to simulate tether compression under LP initial equilibrium conditions is designed to solve the configuration maintaining control problem. Control effects are verified by numerical simulation compared with uncontrolled situation. Simulation results show that the configuration of the three-body ring tethered system could maintain under this active control strategy.

  2. 30 CFR 250.109 - What documents must I prepare and maintain related to welding?

    Science.gov (United States)

    2010-07-01

    ... related to welding? 250.109 Section 250.109 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF... Performance Standards § 250.109 What documents must I prepare and maintain related to welding? (a) You must submit a Welding Plan to the District Manager before you begin drilling or production activities on...

  3. Identification of usable maintainers and restorers for new CMS lines of rice (O. sativa L.

    Directory of Open Access Journals (Sweden)

    Shivakumar, N.*, C. Devaraja, H.C. Lohithaswa, D.K. Sidde Gowda and R.S. Kulkarni

    2010-07-01

    Full Text Available The success of hybrid rice technology depends on the extent of heterosis realized and the grain quality of rice. Seven new CMSlines developed at Zonal Agricultural Research Station, Mandya through backcross breeding were evaluated along with twochecks CRMS31A and CRMS 32A for their morphological and floral traits besides aroma during kharif 2008. All the CMSlines evaluated exhibited complete pollen sterility and spikelet sterility. KCMS 29A recorded the higher stigma exsertion(30.31% and natural outcrossing (19.76%. KCMS 31A had the longest style (1.26 mm and stigma (1.20 mm while the anglebetween stigma lobes was wider ( 65.48 (φ in KCMS 37A which also had the best panicle exsertion (79.28%. All the nineCMS lines had no aroma. Based on morphological and floral traits CMS lines KCMS 29A, KCMS 31A and KCMS 37A werebetter compared to the checks CRMS 31A and CRMS 32A. To identify usable maintainers and restorers for these CMS lineseleven testers were crossed with all the nine CMS lines in a line x tester fashion. Based on the percent spikelet fertility inhybrids, 60 showed restorer reaction and eight had maintainer reaction while the rest 31 showed partial maintainer / restorerreaction. Among the testers MSN-20-13, MSN-62, MSN-63, MSN-64 and MSN 68 were identified as good maintainers whileKMR-3, KMR-4, MSN-67 and MSN-69 as good restorers.

  4. 37 CFR 10.22 - Maintaining integrity and competence of the legal profession.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Maintaining integrity and competence of the legal profession. 10.22 Section 10.22 Patents, Trademarks, and Copyrights UNITED STATES... integrity and competence of the legal profession. (a) A practitioner is subject to discipline if...

  5. Critical Issue Bibliography (CRIB) Sheet: Maintaining Financial Health--Tuition Strategies, Cost Containment, and Fundraising.

    Science.gov (United States)

    ERIC Clearinghouse on Higher Education, Washington, DC.

    This CRitical Issue Bibliography (CRIB) Sheet lists resources that focus on maintaining the financial health of an institution of higher education. It describes resources in three areas: (1) tuition strategies; (2) cost containment; and (3) fundraising. The focus of the bibliography, however, is on cost containment and efficiency, and it details…

  6. Creating and Maintaining Student Diversity: Strategies and Challenges for School Leaders

    Science.gov (United States)

    Villavicencio, Adriana

    2016-01-01

    The purpose of this paper was to explore how school leaders can create and maintain student diversity in charter schools. Based on a case study of two racially balanced schools in New York City, this study identifies three strategies that the schools' leaders took to create more student diversity: (1) develop curriculum-centred missions, (2)…

  7. NT-proBNP as a predictor of intradialytichypotension among maintaining hemodialysis patients

    Institute of Scientific and Technical Information of China (English)

    余金波

    2012-01-01

    Objective To assess the risk factors of intradialytichypotension (IDH) among maintaining hemodialysis (MHD) patients and to explore the relation between NTproBNP and IDH,thus to provide clinical evidence for the prevention and treatment of IDH. Methods A total of 202 MHD patients during March

  8. Rabies Virus Maintained by Dogs in Humans and Terrestrial Wildlife, Ceará State, Brazil

    OpenAIRE

    Favoretto, Silvana R.; de Mattos, Cecília C.; de Morais, Nélio B.; Carrieri, Maria Luíza; Rolim, Benedito N.; Silva, Lucia M.; Rupprecht, Charles E.; Durigon, Edison L.; Carlos A. de Mattos

    2006-01-01

    Rabies viruses circulating in Ceará, Brazil, were identified by molecular analysis to be related to variants maintained by dogs, bats, and other wildlife. Most of these viruses are associated with human rabies cases. We document the emergence of a rabies virus variant responsible for an independent epidemic cycle in the crab-eating fox (Cerdocyon thous).

  9. 77 FR 72431 - Application for a Presidential Permit To Operate and Maintain Pipeline Facilities on the Border...

    Science.gov (United States)

    2012-12-05

    ... Application for a Presidential Permit To Operate and Maintain Pipeline Facilities on the Border of the United... Presidential Permit to Operate and Maintain Pipeline Facilities on the Border of the United States and Canada... LPG Services, L.P. (``Plains LPG'') to operate and maintain pipeline facilities it has acquired at...

  10. 77 FR 67056 - Application for a Presidential Permit To Operate and Maintain Pipeline Facilities on the Border...

    Science.gov (United States)

    2012-11-08

    ... Application for a Presidential Permit To Operate and Maintain Pipeline Facilities on the Border of the United... Presidential Permit to Operate and Maintain Pipeline Facilities on the Border of the United States and Canada... maintain a pipeline (``Line 20'') consisting of approximately 1350 feet of 12-inch diameter pipeline...

  11. 77 FR 72430 - Application for a Presidential Permit To Operate and Maintain Pipeline Facilities on the Border...

    Science.gov (United States)

    2012-12-05

    ... Application for a Presidential Permit To Operate and Maintain Pipeline Facilities on the Border of the United... Presidential Permit to Operate and Maintain Pipeline Facilities on the Border of the United States and Canada... Services, L.P. (Plains LPG) to operate and maintain facilities it has acquired pertaining to six...

  12. Does practicing hatha yoga satisfy recommendations for intensity of physical activity which improves and maintains health and cardiovascular fitness?

    Directory of Open Access Journals (Sweden)

    Rundle Andrew

    2007-11-01

    Full Text Available Abstract Background Little is known about the metabolic and heart rate responses to a typical hatha yoga session. The purposes of this study were 1 to determine whether a typical yoga practice using various postures meets the current recommendations for levels of physical activity required to improve and maintain health and cardiovascular fitness; 2 to determine the reliability of metabolic costs of yoga across sessions; 3 to compare the metabolic costs of yoga practice to those of treadmill walking. Methods In this observational study, 20 intermediate-to-advanced level yoga practitioners, age 31.4 ± 8.3 years, performed an exercise routine inside a human respiratory chamber (indirect calorimeter while wearing heart rate monitors. The exercise routine consisted of 30 minutes of sitting, 56 minutes of beginner-level hatha yoga administered by video, and 10 minutes of treadmill walking at 3.2 and 4.8 kph each. Measures were mean oxygen consumption (VO2, heart rate (HR, percentage predicted maximal heart rate (%MHR, metabolic equivalents (METs, and energy expenditure (kcal. Seven subjects repeated the protocol so that measurement reliability could be established. Results Mean values across the entire yoga session for VO2, HR, %MHR, METs, and energy/min were 0.6 L/kg/min; 93.2 beats/min; 49.4%; 2.5; and 3.2 kcal/min; respectively. Results of the ICCs (2,1 for mean values across the entire yoga session for kcal, METs, and %MHR were 0.979 and 0.973, and 0.865, respectively. Conclusion Metabolic costs of yoga averaged across the entire session represent low levels of physical activity, are similar to walking on a treadmill at 3.2 kph, and do not meet recommendations for levels of physical activity for improving or maintaining health or cardiovascular fitness. Yoga practice incorporating sun salutation postures exceeding the minimum bout of 10 minutes may contribute some portion of sufficiently intense physical activity to improve cardio

  13. Role of technical support organizations in development and maintaining knowledge management systems for Russian regulatory body

    International Nuclear Information System (INIS)

    Full text: The task of maintaining knowledge in the field of atomic energy is one of the most important challenges of today. The development of science and technology has reached a level when passing the accumulated knowledge becomes labor- and resource-consuming, demanding for significant time expenses, which is conditioned, as we know from the theory of knowledge management, by an inevitable process of transformation of knowledge when passing it from one individual to another. Under such circumstances, proper attention should be given to the problem of knowledge maintenance and transfer. The responsibility of the state nuclear safety regulatory authority that oversees how properly the facilities ensure safety requires highly competent experts of the regulatory authority and constant and complete use of the experience in regulatory activities (including theoretical knowledge and practice), which is possible only if there is a well thought-out and effective knowledge management system. Considering the limited resources of the regulatory authority itself, one of possible ways of accomplishing the task is involvement of a technical support organization (TSO) in development and maintenance of the knowledge management system. Such an approach is a practice in a number of countries, which was repeatedly pointed out by the speakers at the International Conference on the Challenges Faced by Technical and Scientific Support Organizations in Enhancing Nuclear Safety held in April 2007 in France. The Russian nuclear and radiation safety regulatory authority is not an exception. Its technical support organization, FSUE VO 'Safety', is directly involved in implementation of the regulator's task of continuing enhancement of the level of competence of its experts by means of development of a knowledge management system. It should be noted that the way our organization approaches the knowledge management system is an obligatory combination of two subsystems - educational and

  14. State Energy Data Report, 1991: Consumption estimates

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-01

    The State Energy Data Report (SEDR) provides annual time series estimates of State-level energy consumption by major economic sector. The estimates are developed in the State Energy Data System (SEDS), which is maintained and operated by the Energy Information Administration (EIA). The goal in maintaining SEDS is to create historical time series of energy consumption by State that are defined as consistently as possible over time and across sectors. SEDS exists for two principal reasons: (1) to provide State energy consumption estimates to the Government, policy makers, and the public; and (2) to provide the historical series necessary for EIA`s energy models.

  15. Maintaining knife sharpness in industrial meat cutting: A matter of knife or meat cutter ability.

    Science.gov (United States)

    Karltun, J; Vogel, K; Bergstrand, M; Eklund, J

    2016-09-01

    Knife sharpness is imperative in meat cutting. The aim of this study was to compare the impact of knife blade steel quality with meat cutters' individual ability to maintain the cutting edge sharp in an industrial production setting. Twelve meat cutters in two different companies using three different knives during normal production were studied in this quasi-experimental study. Methods included were measuring knife cutting force before and after knife use, time knives were used, ratings of sharpness and discomfort and interviews. Results showed that the meat cutters' skill of maintaining sharpness during work had a much larger effect on knife sharpness during work than the knife steel differences. The ability was also related to feelings of discomfort and to physical exertion. It was found that meat cutters using more knives were more likely to suffer from discomfort in the upper limbs, which is a risk for developing MSD. PMID:27184316

  16. Bridgeness: A Local Index on Edge Significance in Maintaining Global Connectivity

    CERN Document Server

    Cheng, Xue-Qi; Shen, Hua-Wei; Zhang, Zi-Ke; Zhou, Tao

    2010-01-01

    Edges in a network can be divided into two kinds according to their different roles: some enhance the locality like the ones inside a cluster while others contribute to the global connectivity like the ones connecting two clusters. Recent study uncovered the weak ties effects in mobile communication [J. P. Onnela et al., Proc. Natl. Acad. Sci. U.S.A. 104, 7332 (2007)]. In this article, we provide complementary results on document networks, that is, the edges connecting less similar nodes in content are more significant in maintaining the global connectivity. We propose an index named bridgeness to quantify the edge significance in maintaining connectivity, which only depends on local information of network topology. We compare the bridgeness with content similarity and some other structural indices according to an edge percolation process. Experimental results on document networks show that the bridgeness outperforms content similarity in characterizing the edge significance. Furthermore, extensive numerical ...

  17. Fractal features of dark, maintained, and driven neural discharges in the cat visual system

    CERN Document Server

    Lowen, S B; Kaplan, E; Saleh, B E A; Teich, M C; Lowen, Steven B.; Ozaki, Tsuyoshi; Kaplan, Ehud; Saleh, Bahaa E. A.; Teich, Malvin C.

    1999-01-01

    We employ a number of statistical measures to characterize neural discharge activity in cat retinal ganglion cells (RGCs) and in their target lateral geniculate nucleus (LGN) neurons under various stimulus conditions, and we develop a new measure to examine correlations in fractal activity between spike-train pairs. In the absence of stimulation (i.e., in the dark), RGC and LGN discharges exhibit similar properties. The presentation of a constant, uniform luminance to the eye reduces the fractal fluctuations in the RGC maintained discharge but enhances them in the target LGN discharge, so that neural activity in the pair no longer mirror each other. A drifting-grating stimulus yields RGC and LGN driven spike trains similar in character to those observed in the maintained discharge, with two notable distinctions: action potentials are reorganized along the time axis so that they occur only during certain phases of the stimulus waveform, and fractal activity is suppressed. Under both uniform-luminance and drift...

  18. An experience of intervention for maintaining the employment of disabled workers

    Directory of Open Access Journals (Sweden)

    Evandro Fornasier

    2014-09-01

    Full Text Available This article describes an active policy intervention in terms of integration into the labor of persons with disabilities, providing job maintaining support. Intervention was conducted using typical psychologist instruments using theoretical principles like multipersonal fields, community-based mental health and group analysis in psychosocial declination. This type of intervention although is not currently counted among the consolidated practices, could be considered as a "product" relevant to the psychologist's social mandate as long as it satisfies the needs and respond to the potential questions, expressed by social or / and by institutions. It also responds to indications provided by international organizations, about rights of persons with disabilities and categories at a social risk.Keywords: Disability and work; Job maintaining; Community-based mental health; Groups and work; Variable settings

  19. Sex determination in honeybees: two separate mechanisms induce and maintain the female pathway

    DEFF Research Database (Denmark)

    Gempe, Tanja; Hasselmann, Martin; Schiøtt, Morten;

    2009-01-01

    Organisms have evolved a bewildering diversity of mechanisms to generate the two sexes. The honeybee (Apis mellifera) employs an interesting system in which sex is determined by heterozygosity at a single locus (the Sex Determination Locus) harbouring the complementary sex determiner (csd) gene...... the regulatory interactions of genes involved in the sex determination pathway. We show that heterozygous csd is only required to induce the female pathway, while the feminizer (fem) gene maintains this decision throughout development. By RNAi induced knockdown we show that the fem gene is essential...... for entire female development and that the csd gene exclusively processes the heterozygous state. Fem activity is also required to maintain the female determined pathway throughout development, which we show by mosaic structures in fem-repressed intersexuals. We use expression of Fem protein in males...

  20. Maintaining semen quality by improving cold chain equipment used in cattle artificial insemination

    Science.gov (United States)

    Lieberman, Daniel; McClure, Elizabeth; Harston, Stephen; Madan, Damian

    2016-06-01

    Artificial insemination of dairy cattle is a common practice in the developing world that can improve farmer incomes and food security. Maintaining the fertilizing potential of frozen semen as it is manipulated, transported and stored is crucial to the success of this process. Here we describe simple technological improvements to protect semen from inadvertent thermal fluctuations that occur when users mishandle semen using standard equipment. We show that when frozen semen is mishandled, characteristics of semen biology associated with fertility are negatively affected. We describe several design modifications and results from thermal performance tests of several improved prototypes. Finally, we compare semen that has been mishandled in standard and improved equipment. The data suggest that our canister improvements can better maintain characteristics of semen biology that correlate with fertility when it is mishandled.

  1. Maintaining a catalog of manually-indexed, clinically-oriented World Wide Web content.

    Science.gov (United States)

    Hersh, W; Ball, A; Day, B; Masterson, M; Zhang, L; Sacherek, L

    1999-01-01

    With no quality controls and a highly distributed means of posting information, finding high-quality, clinically-oriented content on the World Wide Web can be difficult. Maintaining a catalog of such information can be equally challenging. CliniWeb is a catalog of quality-filtered and clinically-oriented content on the Web designed to enhance access to such information. This paper describes a group of semi-automated tools have been developed to maintain the CliniWeb database. One allows easier identification of content by utilizing Web crawling techniques from high-level pages. Another allows easier selection of content for inclusion and its indexing. A final one checks links to help keep the database current. These are augmented by general plans to adopt more detailed metadata and linkages into the medical literature. PMID:10566468

  2. Atraumatic extraction and immediate implant installation: The importance of maintaining the contour gingival tissues.

    Science.gov (United States)

    Tavarez, Rudys Rodolfo De Jesus; Dos Reis, Washigton Luís Machado; Rocha, Adrycila Teixeira; Firoozmand, Leily Macedo; Bandéca, Matheus Coêlho; Tonetto, Mateus Rodrigues; Malheiros, Adriana Santos

    2013-12-01

    There is an accelerated resorption in the first six months after the extraction of the dental element, both horizontally and vertically. These clinical changes normally undertake the aesthetic result of prosthetic rehabilitation, and implant installation after the extraction can be a resource to decrease resorption. The clinical case described in this paper demonstrates a sequence of clinical atraumatic extraction, and then the Immediate installation provisionalization. It is concluded that when carefully indicated and planned, this technique can provide an immediate result promising with maintaining the tooth gingival contour. How to cite this article: Tavarez RR, Machado dos Reis WL, Rocha AT, Firoozmand LM, Bandéca MC, Tonetto MR, Malheiros AS. Atraumatic extraction and immediate implant installation: The importance of maintaining the contour gingival tissues. J Int Oral Health 2013; 5(6):113-8 . PMID:24453455

  3. Heterodyne Interferometric Temperature Sensor Using a Transverse Zeeman Laser and a Polarization Maintaining Fiber

    Science.gov (United States)

    Kawata, S.; Shigeoka, T.; Okamoto, T.; Minami, S.

    1986-01-01

    A new fiber-optic temperature sesnor using a polarization maintaining fiber and a transverse Zeeman laser based on heterodyne interferometry has been developed. The temperature variation is detected by coupling two orthogonal linear polirization components of a laser beam, each differently phase-modulated during transmitting a birefringent single-mode polarization maintaining fiber. A transverse He-Ne Zeeman laser was developed to achieve heterodyning demodulation of the phase-shift caused by the temperature of the fiber. Experimental result demonstrates that this sensor has the temperature resolution of 0.0032°C with a very wide dynamic range. Besides, this fiber sensor has the advantages of simple construction and ruggedness against pressure turbulence.

  4. Achieving and maintaining biological nitrogen removal via nitrite under normal conditions

    Institute of Scientific and Technical Information of China (English)

    CUI You-wei; PENG Yong-zhen; GAN Xiang-qing; YE Liu; WANG Ya-yi

    2005-01-01

    The principal aim of this paper is to develop an approach to realize stable biological nitrogen removal via nitrite under normal conditions. Validation of the new method was established on laboratory-scale experiments applying the sequencing batch reactor(SBR)activated sludge process to domestic wastewater with low C/N ratio. The addition of sodium chloride(NaCl) to influent was established to achieve nitrite build-up. The high nitrite accumulation, depending on the salinity in influent and the application duration of salt, was obtained in SBRs treating saline wastewater. The maintenance results indicated that the real-time SBRs can maintain stable nitrite accumulation, but conversion from shorter nitrification-denitrification to full nitrification-denitrification was observed after some operation cycles in the other SBR with fixed-time control. The presented method is valuable to offer a solution to realize and to maintain nitrogen removal via nitrite under normal conditions.

  5. Ergothioneine maintains redox and bioenergetic homeostasis essential for drug susceptibility and virulence of Mycobacterium tuberculosis

    Science.gov (United States)

    Saini, Vikram; Cumming, Bridgette M.; Guidry, Loni; Lamprecht, Dirk; Adamson, John H.; Reddy, Vineel P.; Chinta, Krishna C.; Mazorodzo, James; Glasgow, Joel N.; Richard-Greenblatt, Melissa; Gomez-Velasco, Anaximandro; Bach, Horacio; Av-Gay, Yossef; Eoh, Hyungjin; Rhee, Kyu; Steyn, Adrie J.C.

    2016-01-01

    SUMMARY The mechanisms by which Mycobacterium tuberculosis (Mtb) maintains metabolic equilibrium to survive during infection and upon exposure to antimycobacterial drugs are poorly characterized. Ergothioneine (EGT) and mycothiol (MSH) are the major redox buffers present in Mtb, but the contribution of EGT to Mtb redox homeostasis and virulence remains unknown. We report that Mtb WhiB3, a 4Fe-4S redox sensor protein, regulates EGT production and maintains bioenergetic homeostasis. We show that central carbon metabolism and lipid precursors regulate EGT production and that EGT modulates drug sensitivity. Notably, EGT and MSH are both essential for redox and bioenergetic homeostasis. Transcriptomic analyses of EGT and MSH mutants indicate overlapping, but distinct functions of EGT and MSH. Lastly, we show that EGT is critical for Mtb survival in both macrophages and mice. This study has uncovered a dynamic balance between Mtb redox and bioenergetic homeostasis, which critically influences Mtb drug susceptibility and pathogenicity. PMID:26774486

  6. Maintaining the know-how after opt-out consensus: chances and limits

    International Nuclear Information System (INIS)

    Within the next decades, nuclear safety and repository research will continue to be a necessary and integral constituent of the society's provident research. Yet, it is very difficult to maintain this competence in a politically complex environment with the scarce funds available. For its purpose, the Federal Government has appointed an evaluation commission, the chairmanship of which lies with the Federal Ministry of Economics and Technology. In its report of January 2001, the commission emphasised that efforts to adequately maintain competence in nuclear engineering, including industry-independent expert knowledge, will only meet with success, if the Federal Republic of Germany and the federal states contribute to a sufficient and stable financing of non-university research. (orig.)

  7. Information system for maintaining a database of geobotanical descriptions while studying a landscape

    Science.gov (United States)

    Shchukova, K.

    2015-10-01

    Nowadays, there is a need in developing a common information space for providing a centralized data storage of geobotanical descriptions while studying a landscape and custom software for collecting, storing and processing semi-structured data. In the paper, the results of information system development for maintaining a geobotanical database are discussed. The database was developed via the bottom-up design approach and ER-model (Entity- Relationship). The analysis results of geobotanical data obtained from field studies and the database structure of geobotanical descriptions while studying a landscape are considered. At the moment, the information system for maintaining the geobotanical database is applied by the Institute of Steppe, Ural Branch of Russian Academy of Sciences.

  8. Academic portfolio in the digital era: organizing and maintaining a portfolio using reference managers.

    Science.gov (United States)

    Bhargava, Puneet; Patel, Vatsal B; Iyer, Ramesh S; Moshiri, Mariam; Robinson, Tracy J; Lall, Chandana; Heller, Matthew T

    2015-02-01

    The academic portfolio has become an integral part of the promotions process. Creating and maintaining an academic portfolio in paper-based or web-based formats can be a cumbersome and time-consuming task. In this article, we describe an alternative way to efficiently organize an academic portfolio using a reference manager software, and discuss some of the afforded advantages. The reference manager software Papers (Mekentosj, Amsterdam, The Netherlands) was used to create an academic portfolio. The article outlines the key steps in creating and maintaining a digital academic portfolio. Using reference manager software (Papers), we created an academic portfolio that allows the user to digitally organize clinical, teaching, and research accomplishments in an indexed library enabling efficient updating, rapid retrieval, and easy sharing. To our knowledge, this is the first digital portfolio of its kind. PMID:24965274

  9. The sources of self-esteem: Initating and maintaining romantic intimacy at emerging adulthood in Turkey

    Directory of Open Access Journals (Sweden)

    Nilüfer Özabacı

    2015-01-01

    Full Text Available This study examines the relationship of emerging adults’ in initiating and maintaining romantic intimacy with sub-dimensions and explores the extent that self-esteem in emerging adults could explain the initiation and maintenance of a romantic relationship. The participants included 136 male and 106 female totaling 242 university students. In order to collect data, Rosenberg Self-esteem Scale, Markers of Starting Romantic Intimacy Scale and Quality of Relationship Inventory were used. According to the results, emerging adults perceived both having markers of starting romantic intimacy and the positive quality of relationship as significant sources for their self-esteem. The results of the present study emphasize the significance of self-esteem for starting and maintaining romantic intimacy.

  10. THE PRESENTATION OF THE CAPITAL IN FINANCIAL STATEMENTS. THE CONCEPT OF MAINTAINING CAPITAL

    Directory of Open Access Journals (Sweden)

    ANNEE-MARIE GRECEA

    2012-05-01

    Full Text Available The general framework of preparation and presentation of the financial statements as the national legislation, formulates a residual definitionof equity, respectively the right of the shareholders on the assets of anentity after deducting all debts. Thus equity represent the equivalentvalue of inputs which the company must not provide goods or services to a third party. The concept of capital is synonymous with net assets or equity of the company.In the same time, the capital of the company can be addressed through the other two concepts: maintaining financial capital and maintaining physical capital. The selection of one of the two variants has to be realized by the company starting from information users necessities.

  11. Activin A maintains cerebral cortex neuronal survival and increases voltage-gated Na+ neuronal current

    Institute of Scientific and Technical Information of China (English)

    Jingyan Ge; Yinan Wang; Haiyan Liu; Fangfang Chen; Xueling Cui; Zhonghui Liu

    2010-01-01

    Activin A,which was first described in 1986,has been shown to maintain hippocampal neuronal survival.Activin A increases intracellular free Ca2+via L-type Ca2+channels.Our previous study showed that activin A promotes neurite growth of dorsal root ganglia in embryonic chickens and inhibits nitric oxide secretion.The present study demonstrated for the first time that activin A could maintain cerebral cortex neuronal survival in vitro for a tong period,and that activin A was shown to increase voltage-gated Na+current(INa)in Neure-2a cells,which was recorded by patch clamp technique.The present study revealed a novel mechanism for activin A,as well as the influence of activin A on neurons by regulating expressions of vasoactive intestine peptide and inducible nitric oxide synthase.

  12. Keeping it together: Pulmonary alveoli are maintained by a hierarchy of cellular programs.

    Science.gov (United States)

    Logan, Catriona Y; Desai, Tushar J

    2015-09-01

    The application of in vivo genetic lineage tracing has advanced our understanding of cellular mechanisms for tissue renewal in organs with slow turnover, like the lung. These studies have identified an adult stem cell with very different properties than classically understood ones that maintain continuously cycling tissues such as the intestine. A portrait has emerged of an ensemble of cellular programs that replenish the cells that line the gas exchange (alveolar) surface, enabling a response tailored to the extent of cell loss. A capacity for differentiated cells to undergo direct lineage transitions allows for local restoration of proper cell balance at sites of injury. We present these recent findings as a paradigm for how a relatively quiescent tissue compartment can maintain homeostasis throughout a lifetime punctuated by injuries ranging from mild to life-threatening, and discuss how dysfunction or insufficiency of alveolar repair programs produce serious health consequences like cancer and fibrosis. PMID:26201286

  13. Descending facilitatory pathways from the RVM initiate and maintain bilateral hyperalgesia after muscle insult

    OpenAIRE

    Tillu, DV; Gebhart, GF; Sluka, KA

    2007-01-01

    The rostral ventromedial medulla (RVM) is involved in facilitation of spinal nociceptive processing and generation of hyperalgesia in inflammatory and neuropathic pain models. We hypothesized that the bilateral hyperalgesia that develops after repeated intramuscular injections of acidic saline is initiated and maintained by activation of descending facilitatory pathways from the RVM. Male Sprague-Dawley rats were implanted with intracerebral guide cannulae into the nucleus raphe magnus (NRM) ...

  14. PETROCHINA TO MAINTAIN TWO-DIGITAL GROWTH OF ITS GAS PRODUCTION

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Based on the information made available from the recent conference on natural gas development held in Chengdu, the capital of the natural gasenriched Sichuan Province, PetroChina will maintain a 14 percent growth for its natural gas production during the 1 lth Five-Year Plan period (2006-2010), owing to acceleration of the market development and pipeline construction in the downstream sector and rapid progress in the natural gas exploration.

  15. Eco-designing Product Service Systems by degrading functions while maintaining user satisfaction

    OpenAIRE

    Salazar, C.; Lelah, Alan; Brissaud, Daniel

    2015-01-01

    Industrialising products and/or services, considering the current environmental situation, requires changing paradigms to be efficient. The paradigm of proposing systems of products and services instead of selling products is one of them. Moving further, this article shows that it can sometimes be possible to consider product and/or service degradation in order to relieve environmental burdens, while still maintaining user satisfaction. In this new paradigm, degradation will concern certain t...

  16. Supporting cells eliminate dying sensory hair cells to maintain epithelial integrity in the avian inner ear

    OpenAIRE

    Bird, Jonathan E.; Daudet, Nicolas; Mark E Warchol; Gale, Jonathan E.

    2010-01-01

    Epithelial homeostasis is essential for sensory transduction in the auditory and vestibular organs of the inner ear, but how it is maintained during trauma is poorly understood. To examine potential repair mechanisms, we expressed β-actin-EGFP in the chick inner ear and used live-cell imaging to study how sensory epithelia responded during aminoglycoside-induced hair cell trauma. We found that glial-like supporting cells used two independent mechanisms to rapidly eliminate dying hair cells. S...

  17. Maintaining the Identity and Self-Worth in Patients With Severe Illness or Injury

    Directory of Open Access Journals (Sweden)

    Sofia Zyga

    2012-01-01

    Full Text Available Severe illness and injury can change many aspects of people. For this reason, one of the biggest challenges facedby patients is the preservation of their identity. The loss of independence and self-service failure is likely to lead topassivity and depression. Patients should make the necessary adjustments in order to maintain self-esteem and tooptimize their functionality despite the injuries suffered. Social support, health professionals, family and workencourage this change.

  18. Insomnia among methadone-maintained persons: The feasibility of collecting home PSG recordings

    OpenAIRE

    Kurth, Megan E.; Sharkey, Katherine M.; Millman, Richard P.; Corso, Richard P; Stein, Michael D

    2009-01-01

    Sleep disturbance among methadone-maintained patients is highly prevalent. A full understanding of sleep disturbance requires polysomnographic (PSG) measures along with subjective sleep quality measures. The goal of this study was to describe our experiences in performing at-home unattended PSG in this population. Participants had a Pittsburgh Sleep Quality Index (PSQI) score of six or higher, indicating clinically significant insomnia, and sixty five percent of eligible persons agreed to enr...

  19. Maintainability Analysis of Underground Mining Equipment Using Genetic Algorithms: Case Studies with an LHD Vehicle

    OpenAIRE

    Sihong Peng; Nick Vayenas

    2014-01-01

    While increased mine mechanization and automation make considerable contributions to mine productivity, unexpected equipment failures and planned or routine maintenance prohibit the maximum possible utilization of sophisticated mining equipment and require a significant amount of extra capital investment. This paper deals with aspects of maintainability prediction for mining machinery. A PC software called GenRel was developed for this purpose. In GenRel, it is assumed that failures of mining...

  20. Design of polarization-maintaining retro-reflector for folded-path applications

    Institute of Scientific and Technical Information of China (English)

    Zhen Guo; Lianshan Yan; Wei Pan; Bin Luo; KunhuaWen; X. Steve Yao

    2011-01-01

    A design of polarization-maintaining retro-reflectors (PMRRs) for folded-path applications is proposed and analyzed.The prism-based scheme enables the output light,which is parallel to the input,to have an identical state of polarization.The principle of the design is theoretically verified,and the related error is analyzed due to possible manufacturing imperfection.The maximum spatial angle error is ±2.75°.The effect on the extinction ratio and insertion loss is also discussed,which further proves the design's feasibility in practical applications.Polarization maintaining reflectors play an essential role in physical optics and optical communications.However,the phase shift induced by the reflection may affect the state of polarization (SOP) of signals.The SOP is essential information in optical sensors and ellipsometers[1-5].Thus,maintaining the reflecting polarization is crucial and has attracted much attention.However,most of these applications are based on the coating technology[6-9] and the design of photonic crystal[10-13],which are not appropriate in practical applications because of the special equipment or high precision required.Clearly,the most efficient approach to overcome the effect is to employ no-shift instruments[14-16],which are easy to fabricate and implement in practical applications.%A design of polarization-maintaining retro-reflectors (PMRRs) for folded-path applications is proposed and analyzed. The prism-based scheme enables the output light, which is parallel to the input, to have an identical state of polarization. The principle of the design is theoretically verified, and the related error is analyzed due to possible manufacturing imperfection. The maximum spatial angle error is ±2.75°. The effect on the extinction ratio and insertion loss is also discussed, which further proves the design's feasibility in practical applications.

  1. A Template-driven Approach for Maintainable Service-oriented Information Systems Integration

    OpenAIRE

    Pahl, Claus; Zhu, Yaoling; Gacitua-Decar, Veronica

    2009-01-01

    peer-reviewed Service-oriented architecture (SOA) is currently the predominant software integration framework. Web services provide the predominant platform for SOA. SOA as an integration architecture solution supports a range of application scenarios. We present a solution for the integration of business information systems based on SOA and Web services. We discuss maintainability requirements in relation to information-specific integration and architecture aspects. A template-based appro...

  2. Social anxiety disorder in children and adolescents: assessment, maintaining factors, and treatment

    OpenAIRE

    Cederlund, Rio

    2013-01-01

    The present dissertation consists of three empirical studies on social anxiety disorder (SAD) in a sample of Swedish children and adolescents. Based on findings made in a large behavior treatment study, the thesis contributes to the field of research on childhood SAD by investigating a factor that maintains the disorder, ways to measure and screen for diagnosis, and the treatment of the disorder. Study I investigated whether giving an educational course to the parents of socially anxious chil...

  3. ­The Geospatial Metadata Manager’s Toolbox: Three Techniques for Maintaining Records

    OpenAIRE

    Bruce Godfrey; Jeremy Kenyon

    2015-01-01

    Managing geospatial metadata records requires a range of techniques. At the University of Idaho Library, we have tens of thousands of records which need to be maintained as well as the addition of new records which need to be normalized and added to the collections. We show a graphical user interface (GUI) tool that was developed to make simple modifications, a simple XSLT that operates on complex metadata, and a Python script with enables parallel processing to make maintenance tasks more ...

  4. WAYS TO MAINTAIN SUSTAINABLE SYSTEM OF MANAGING REPUTATIONAL RISKS WITHIN SUPPLIERS RELATIONS

    OpenAIRE

    Iznova, Taisiya; Efimova, Olga

    2013-01-01

    Reputational risk is the main threat to one’s ability to maintain sustainable development because it influences company’s long-standing position. However, very little empirical research has been carried out to determine how to manage reputational risk using sustainability reporting. This paper addresses the problem of reputational risk within supplier relations system. The paper proposes an approach based on identification of key suppliers to understand their needs and expectations and develo...

  5. Maintaining climate change experiments : urban political ecology and the everyday reconfiguration of urban infrastructure.

    OpenAIRE

    Broto, V. C.; Bulkeley, H.

    2013-01-01

    Climate change governance is increasingly being conducted through urban climate change experiments, purposive interventions that seek to reconfigure urban sociotechnical systems to achieve low-carbon and resilient cities. In examining how experiments take effect, we suggest that we need to understand not only how they are made and assembled, but also how they are maintained within specific urban contexts. Drawing on literatures from urban political ecology and the specific debate on urban rep...

  6. The Use of Communication Technologies by Dating Couples to Maintain Romantic Relationship

    OpenAIRE

    Yu-Hsin Teng; Song-In Wang

    2015-01-01

    This study tried to investigate how the dating couples use communication technologies to maintain their romantic relationship. We hypothesized that time of dating, distance of dating and satisfaction of relationship will affect the positive or negative relationship maintenance behaviors. An online survey and in-depth interviews were utilized to test the hypotheses and explain the results. A total of 356 valid questionnaires were collected and seven respondents were interviewed. The main findi...

  7. Homeodomain transcription factor and tumor suppressor Prep1 is required to maintain genomic stability

    OpenAIRE

    Iotti, Giorgio; Longobardi, Elena; Masella, Silvia; Dardaei, Leila; De Santis, Francesca; Micali, Nicola; Blasi, Francesco

    2011-01-01

    Prep1 is a homeodomain transcription factor that is essential in embryonic development and functions in the adult as a tumor suppressor. We show here that Prep1 is involved in maintaining genomic stability and preventing neoplastic transformation. Hypomorphic homozygous Prep1i/i fetal liver cells and mouse embryonic fibroblasts (MEFs) exhibit increased basal DNA damage and normal DNA damage response after γ-irradiation compared with WT. Cytogenetic analysis shows the presence of numerous chro...

  8. Maintaining stability in a changing financial system: some lessons relearned again?

    OpenAIRE

    Thomas M. Hoenig

    2008-01-01

    Over the past three decades, we have experienced an increased number of financial crises in many countries around the world. These crises have taken place in many different parts of the financial system, including: banking and payments systems, housing finance systems, securities markets, and currency markets. Central banks and other authorities charged with maintaining financial stability have drawn important lessons from each of these crises and have instituted regulatory and policy changes...

  9. Maintaining the Identity and Self-Worth in Patients With Severe Illness or Injury

    OpenAIRE

    Sofia Zyga

    2012-01-01

    Severe illness and injury can change many aspects of people. For this reason, one of the biggest challenges facedby patients is the preservation of their identity. The loss of independence and self-service failure is likely to lead topassivity and depression. Patients should make the necessary adjustments in order to maintain self-esteem and tooptimize their functionality despite the injuries suffered. Social support, health professionals, family and workencourage this change.

  10. The Lyophilization Process Maintains the Chemical and Biological Characteristics of Royal Jelly

    OpenAIRE

    Andresa Piacezzi Nascimento; Larissa Ariana Roveroni Moraes; Nathália Ursoli Ferreira; Gabriela de Padua Moreno; Fernanda Grassi Mangolini Uahib; Edna Aparecida Barizon; Andresa Aparecida Berretta

    2015-01-01

    The alternative use of natural products, like royal jelly (RJ), may be an important tool for the treatment of infections caused by antibiotic-resistant bacteria. RJ presents a large number of bioactive substances, including antimicrobial compounds. In this study, we carried out the chemical characterization of fresh and lyophilized RJ and investigated their antibacterial effects with the purpose of evaluating if the lyophilization process maintains the chemical and antibacterial properties of...

  11. Metabolic activity and enzyme induction in rat fecal microflora maintained in continuous culture.

    OpenAIRE

    Mallett, A K; Bearne, C A; Rowland, I R

    1983-01-01

    The enzyme activity of the rat hindgut microflora maintained in an anaerobic two-stage continuous culture was compared with that of rat cecal contents. A qualitative comparison (API ZYM) showed a high degree of similarity between the two populations. Quantitative determinations showed that azoreductase, beta-glucosidase, nitrate reductase, and nitroreductase activities were comparable, and that beta-glucuronidase activity was very low in the culture. beta-Glucuronidase, beta-glucosidase, and ...

  12. Gossip Versus Punishment: The Efficiency of Reputation to Promote and Maintain Cooperation

    OpenAIRE

    Junhui Wu; Daniel Balliet; Van Lange, Paul A. M.

    2016-01-01

    Prior theory suggests that reputation spreading (e.g., gossip) and punishment are two key mechanisms to promote cooperation in groups, but no behavioral research has yet examined their relative effectiveness and efficiency in promoting and maintaining cooperation. To examine these issues, we observed participants interacting in a four-round public goods game (PGG) with or without gossip and punishment options, and a subsequent two-round trust game (TG). We manipulated gossip as the option to ...

  13. Methadone-Maintained Pregnant Patients and Current Mood Disorder: Delivery and Neonatal Outcomes

    OpenAIRE

    Tuten, Michelle; Heil, Sarah H.; O'Grady, Kevin E.; Fitzsimons, Heather; Chisolm, Margaret S.; Jones, Hendrée E.

    2009-01-01

    Methadone-maintained pregnant patients with mood disorders have compromised treatment outcomes (1). This study examined the relationship between the presence of mood disorders and delivery and neonatal outcomes. Participants were categorized into two groups: no current mood disorder (n=30) or primary mood disorder (n=38). The mood disorder group reported more serious lifetime and current depression than did the no current mood disorder group. Neonates from mothers with mood disorders had a lo...

  14. Strategies for maintaining emotional stability: The case of nurses in private health care industry

    OpenAIRE

    Pushpika Subhashinie Mullakanda; Kumudinei Dissanayake

    2015-01-01

    This study examines the emotional intelligence (EI) of nurses by differentiating inter-personal and intra-personal dimensions, and explores the measures taken by them to maintain emotional stability. Further, it investigates the relationship of demographic factors (age, gender and year of experience) of nurses with their emotional stability. The case organization is a well performing private hospital located closer to the metropolitan city. Study collects data through both quantitative (surve...

  15. Excitatory Effects of Parvalbumin-Expressing Interneurons Maintain Hippocampal Epileptiform Activity via Synchronous Afterdischarges

    OpenAIRE

    Ellender, Tommas J.; Raimondo, Joseph V.; Irkle, Agnese; Karri P Lamsa; Akerman, Colin J.

    2014-01-01

    Epileptic seizures are characterized by periods of hypersynchronous, hyperexcitability within brain networks. Most seizures involve two stages: an initial tonic phase, followed by a longer clonic phase that is characterized by rhythmic bouts of synchronized network activity called afterdischarges (ADs). Here we investigate the cellular and network mechanisms underlying hippocampal ADs in an effort to understand how they maintain seizure activity. Using in vitro hippocampal slice models from r...

  16. Maintaining Work: The Influence of Child Care Subsidies on Child Care-Related Work Disruptions

    OpenAIRE

    Forry, Nicole D.; Hofferth, Sandra L.

    2011-01-01

    With the passage of welfare reform, support for low-income parents to not only obtain, but maintain work has become imperative. The role of child care subsidies in supporting parents’ job tenure has received little attention in the literature. This article examines the association between receiving a child care subsidy and experiencing a child care-related work disruption using two samples and both cross-sectional and longitudinal regression models. Child care-related work disruptions are fou...

  17. An approach to maintaining qualification of Class-1E equipment in the mild environment

    International Nuclear Information System (INIS)

    In a paper presented at the February 1983 IEEE Winter Power Conference in New York, the authors presented a method of qualifying Class-1E equipment in the so-called ''mild environment'' (Vol. PAS-102, No. 8) WM017-1. This presentation discusses a method for surveillance and testing that may be used to maintain equipment qualification in the mild environment, which when used in conjunction with the aforementioned paper will provide the total concept

  18. A process to maintain the quality of a computerized knowledge base.

    OpenAIRE

    Kuperman, G. J.; Fiskio, J. M.; Karson, A.

    1999-01-01

    As part of a project to develop knowledge-based reminders for the outpatient setting, we developed a process to help maintain the quality of the knowledge base. The knowledge engineering process involved many parties, including several domain experts, a knowledge engineer, and a programmer and a process was necessary to assure that information transfer among individuals did not become confused. An MS Access database was created to store, among other data, textual versions of the rules as they...

  19. Phosphorylation of CPAP by Aurora-A Maintains Spindle Pole Integrity during Mitosis

    OpenAIRE

    En-Ju Chou; Liang-Yi Hung; Chieh-Ju C. Tang; Wen-Bin Hsu; Hsin-Yi Wu; Pao-Chi Liao; Tang K. Tang

    2016-01-01

    CPAP is required for centriole elongation during S/G2 phase, but the role of CPAP in mitosis is incompletely understood. Here, we show that CPAP maintains spindle pole integrity through its phosphorylation by Aurora-A during mitosis. Depletion of CPAP induced a prolonged delay in mitosis, pericentriolar material (PCM) dispersion, and multiple mitotic abnormalities. Further studies demonstrated that CPAP directly interacts with and is phosphorylated by Aurora-A at serine 467 during mitosis. In...

  20. Efficiently Maintaining Distributed Model-Based Views on Real-Time Data Streams

    OpenAIRE

    Arion, Petre Alexandru; Jeung, Ho Young; Aberer, Karl; Michel, Sebastian

    2011-01-01

    Minimizing communication cost is a fundamental problem in large-scale federated sensor networks. Existing solutions applicable for the problem are often ad-hoc for specific query types, or they are inefficient when query results contain large volumes of data to be transferred over the networks. Maintaining model-based views of data streams has been recently highlighted because it permits the data communication over networks to be efficient by transmitting parameter values for the models, inst...

  1. Efficiently Maintaining Distributed Model-Based Views on Real-Time Data Streams

    OpenAIRE

    Arion, Petre Alexandru; Jeung, Ho Young; Aberer, Karl

    2011-01-01

    Minimizing communication cost is a fundamental problem in large-scale federated sensor networks. Maintaining model-based views of data streams has been highlighted because it permits efficient data communication by transmitting parameter values of models, instead of original data streams. We propose a framework that employs the advantages of using model-based views for communication-efficient stream data processing over federated sensor networks, yet it significantly improves state-of-the-art...

  2. AN OPTION PERSPECTIVE ON GENERATING AND MAINTAINING PLANT VARIETY RIGHTS IN CHINA

    OpenAIRE

    Koo, Bonwoo; Pardey, Philip G.; Qian, Keming; Zhang, Yi

    2003-01-01

    Notwithstanding the ambiguous research and productivity promoting effects of plant variety protections (PVPs), even in developed countries, many developing countries have adopted PVPs in the past few years, in part to comply with their Trade-Related Aspects of Intellectual Property Rights (TRIPS) obligations. Seeking and maintaining PVPs reserves options to an expected revenue stream from the future sale of protected varieties, the value of which varies for a host of reasons. In this paper we...

  3. Maintaining Brain Health by Monitoring Inflammatory Processes: a Mechanism to Promote Successful Aging

    OpenAIRE

    Rosano, Caterina; Marsland, Anna L.; Gianaros, Peter J.

    2011-01-01

    Maintaining brain health promotes successful aging. The main determinants of brain health are the preservation of cognitive function and remaining free from structural and metabolic abnormalities, including loss of neuronal synapses, atrophy, small vessel disease and focal amyloid deposits visible by neuroimaging. Promising studies indicate that these determinants are to some extent modifiable, even among adults seventy years and older. Converging animal and human evidence further suggests th...

  4. Clues to maintaining calorie restriction? Psychosocial profiles of successful long-term restrictors

    OpenAIRE

    Belsky, ACI; Epel, ES; Tomiyama, AJ

    2014-01-01

    To combat the obesity epidemic, interventions and treatments often recommend low-calorie dieting. Calorie restriction (CR) as a weight intervention, however, is often unsuccessful, as most people cannot sustain the behavior. Yet one small group has maintained extreme CR over years - members of the CR Society and followers of The CR Way. This study examined stable psychosocial characteristics of these individuals to identify traits that may promote success at long-term CR. In 65 participants, ...

  5. PRACTICING ALTERNATIVE FORMS OF TOURISM FOR MAINTAINING HEALTH IN AREAS OF GORJ

    OpenAIRE

    Camelia Daniela Plăstoi; Roxana Gabriela Popa

    2011-01-01

    Climate of the mountain body improves health through ozone and negative ions, whose ratio is three times higher in the mountain air, than in plain air. Leisure activities practiced in Rinca and Sohodol ecotourism areas are: respiratory therapy, hiking, jogging, cycling and gymnastics exercises. Ecotourism areas are areas where you can practice a form of alternative tourism, which aims at protecting and maintaining a manageable size products impacts on the environment. Ecotourism a...

  6. The sources of self-esteem: Initating and maintaining romantic intimacy at emerging adulthood in Turkey

    OpenAIRE

    Nilüfer Özabacı; Ali Eryılmaz

    2015-01-01

    This study examines the relationship of emerging adults’ in initiating and maintaining romantic intimacy with sub-dimensions and explores the extent that self-esteem in emerging adults could explain the initiation and maintenance of a romantic relationship. The participants included 136 male and 106 female totaling 242 university students. In order to collect data, Rosenberg Self-esteem Scale, Markers of Starting Romantic Intimacy Scale and Quality of Relationship Inventory were used. Accordi...

  7. Modeling and Simulation of Reliability & Maintainability Parameters for Reusable Launch Vehicles using Design of Experiments

    Science.gov (United States)

    Unal, Resit; Morris, W. Douglas; White, Nancy H.; Lepsch, Roger A.

    2004-01-01

    This paper describes the development of a methodology for estimating reliability and maintainability distribution parameters for a reusable launch vehicle. A disciplinary analysis code and experimental designs are used to construct approximation models for performance characteristics. These models are then used in a simulation study to estimate performance characteristic distributions efficiently. The effectiveness and limitations of the developed methodology for launch vehicle operations simulations are also discussed.

  8. CD8+ T Cells Maintain Suppression of Simian Immunodeficiency Virus in the Central Nervous System

    OpenAIRE

    Marcondes, Maria Cecilia G.; Morsey, Brenda; Emanuel, Katy; Lamberty, Benjamin G.; Flynn, Claudia T.; Fox, Howard S.

    2014-01-01

    Human immunodeficiency virus (HIV) accesses the brain early in infection and can lead to neurocognitive disorders. The brain can also serve as a viral reservoir, but how virus is controlled in the brain is unknown. To examine this, CD8-depleting monoclonal antibody was injected into the cerebrospinal fluid of rhesus monkeys with chronic simian immunodeficiency virus (SIV) infection. This treatment led to the rapid increase of SIV in the brain. Virus in the brain is maintained by active suppre...

  9. Dynactin is required to maintain nuclear position within postmitotic Drosophila photoreceptor neurons

    OpenAIRE

    Whited, Jessica L.; Cassell, Andre; Brouillette, Monique; Garrity, Paul A.

    2004-01-01

    How a nucleus is positioned within a highly polarized post-mitotic animal cell is not well understood. In this work, we demonstrate that the Dynactin complex (a regulator of the microtubule motor protein Dynein) is required to maintain the position of the nucleus within post-mitotic Drosophila melanogaster photoreceptor neurons. We show that multiple independent disruptions of Dynactin function cause a relocation of the photoreceptor nucleus toward the brain, and that inhibiting Dynactin caus...

  10. Id1 restrains myeloid commitment, maintaining the self-renewal capacity of hematopoietic stem cells

    OpenAIRE

    Jankovic, Vladimir; Ciarrocchi, Alessia; Boccuni, Piernicola; Deblasio, Tony; Benezra, Robert; Nimer, Stephen D.

    2007-01-01

    Appropriate hematopoietic stem cell (HSC) self-renewal reflects the tight regulation of cell cycle entry and lineage commitment. Here, we show that Id1, a dominant-negative regulator of E protein transcription factors, maintains HSC self-renewal by preserving the undifferentiated state. Id1-deficient HSCs show increased cell cycling, by BrdU incorporation in vivo, but fail to efficiently self-renew, leading to low steady-state HSC numbers and premature exhaustion in serial bone marrow transpl...

  11. Education and training in nuclear technology. Maintaining competence in times of the German 'Energiewende'

    International Nuclear Information System (INIS)

    The final storage of nuclear waste in Germany right now is more a political and societal than technical process. To promote the exchange of experience in the sophisticated field of mining technology, and put the focus back on finding a repository solution, the DMT in cooperation with GNS and DBE Technology initiated the Essen Specialized Discussions about Repository Mining. On February 28, more than 120 participants sought information about recent developments, exchanged experience, and maintained contacts. (orig.)

  12. Effects of presession attention on the frequency of attention-maintained behavior.

    OpenAIRE

    O'Reilly, M F

    1999-01-01

    The effect of prior attention was systematically manipulated to study its influence on rates of yelling and head hitting, both maintained by positive reinforcement in the form of attention. Higher levels of head hitting occurred in analogue attention conditions when the person was deprived of attention (no social interactions for 1 hr) prior to the analysis in comparison to when the person received high levels of attention (attention delivered on a fixed-time 30-s schedule for 1 hr) prior to ...

  13. A tunable comb filter using single-mode/multimode/polarization-maintaining-fiber-based Sagnac fiber loop

    Institute of Scientific and Technical Information of China (English)

    Ruan Juan; Zhang Wei-Gang; Zhang Hao; Geng Peng-Cheng; Bai Zhi-Yong

    2013-01-01

    A novel tunable comb filter composed of a single-mode/multimode/polarization-maintaining-fiber-based Sagnac fiber loop is proposed and experimentally demonstrated.The filter tunability is achieved by rotating the polarization controller.The spectral shift is dependent on rotation direction and the position of the polarization controller.In addition,the adjustable range achieved by rotating the half-wave-plate polarization controller is twice higher than that of the quarter-wave-plate one.

  14. Maintaining a Life of Subsistence in the Bemba Village of Northeastern Zambia

    OpenAIRE

    SUGIYAMA, Yuko

    1987-01-01

    The Bemba people, who are living in the woodland area of northeastern Zambia, have developed a unique slash-and-burn cultivation system, called citemene system. It is now censured as the cause of deforestation and the Bemba people are faced with agricultural modernization. There are some villages where people have been maintaining a life of subsistence based on citemene, while other villages have introduced modern agriculture. This paper aims to provide a clear picture of the "traditional" li...

  15. Are Improvements Maintained after In-Home Pulmonary Telerehabilitation for Patients with Chronic Obstructive Pulmonary Disease?

    OpenAIRE

    Nicole Marquis; Pierre Larivée; Marie-France Dubois; Michel Tousignant

    2015-01-01

    This study investigated if improvements can be maintained over 24 weeks when in-home pulmonary telerehabilitation is combined with asynchronous self-management education for Chronic Obstructive Pulmonary Disease (COPD). Twenty-three community-living elders with moderate to very severe COPD participated in a pre/post-intervention study. Over 8 weeks, they had access to self-learning capsules on self-management, received 15 in-home teletreatment sessions and were encouraged to gradually engage ...

  16. ATR cooperates with CTC1 and STN1 to maintain telomeres and genome integrity in Arabidopsis

    OpenAIRE

    Boltz, Kara A.; Leehy, Katherine; Song, Xiangyu; Nelson, Andrew D.; Shippen, Dorothy E.

    2012-01-01

    The CTC1/STN1/TEN1 (CST) complex is an essential constituent of plant and vertebrate telomeres. Here we show that CST and ATR (ataxia telangiectasia mutated [ATM] and Rad3-related) act synergistically to maintain telomere length and genome stability in Arabidopsis. Inactivation of ATR, but not ATM, temporarily rescued severe morphological phenotypes associated with ctc1 or stn1. Unexpectedly, telomere shortening accelerated in plants lacking CST and ATR. In first-generation (G1) ctc1 atr muta...

  17. Coprecipitation of nonoxynol-9 with polyvinylpyrrolidone to decrease vaginal irritation potential while maintaining spermicidal potency

    OpenAIRE

    Fowler, Philip T.; Doncel, Gustavo F.; Bummer, Paul M.; Digenis, George A.

    2003-01-01

    The aim of this study was to test the hypothesis that polyvinylpyrrolidone (PVP) would increase the critical micelle concentration (CMC) of nonoxynol-9 (N-9), providing a reduction in its irritation potential, while maintaining essential spermicidal activity. Solid coprecipitates of N-9 with PVP were manufactured with the use of a modified lyophilization process. The irritation potential of N-9 was estimated by an in vitro assay, monitoring the extent of hemolysis of red blood cells. CMCs of ...

  18. Prophets and Preference: Constructing and Maintaining a Homosexual Identity in the Mormon Church

    OpenAIRE

    Richard D. Phillips

    1993-01-01

    This thesis is a descriptive ethnography of homosexuals and homosexuality in the Church of Jesus Christ of Latter-day Saints, or Mormon church, The study employs the labeling perspective in sociology and uses gay Mormons to examine how an individual constructs and maintains a homosexual identity in an environment where such an orientation is stigmatized and devalued. Qualitative interviews and documentary analysis are the chief methodological tools for this study. The contradictions betwe...

  19. An artificial neural network for modeling reliability, availability and maintainability of a repairable system

    International Nuclear Information System (INIS)

    The paper explores the application of artificial neural networks to model the behaviour of a complex, repairable system. A composite measure of reliability, availability and maintainability parameters has been proposed for measuring the system performance. The artificial neural network has been trained using past data of a helicopter transportation facility. It is used to simulate behaviour of the facility under various constraints. The insights obtained from results of simulation are useful in formulating strategies for optimal operation of the system

  20. Coupling Charactor of Polarization Maintaining Optical Fiber Under the Condition of Bend①②

    Institute of Scientific and Technical Information of China (English)

    LIChangchun; LUOFei; 等

    1997-01-01

    In the field of optical fiber communication and sensing,polarization maintaining optical fiber with special polarization wave transmit character has been taken more and more attentions.It is more mportant of couple between polarization modes,with the help of microdisturbed and coupled mode theories ,the couples characters of high birefracting Bow-Tie optical fiber in the condition of pure bend are analysed,and power coupling relationships between transmit modes are also derivated.

  1. Application support for managing and maintaining the mould sets with teflon coating

    OpenAIRE

    CVETEK, ERIK

    2015-01-01

    The objective of my thesis is to make an application for managing and maintaining tools with Teflon coating (mouldsets), which are used in automotive industry of cabin, round air and oil filters. Main purpose of the application is to enable the overview with end of life status of Teflon coating, preventive maintenance, checkup of tools and in the end, creation of electronic order for refurbishing the Teflon coating before it gets used up. The application was designed to meet the criteria desc...

  2. How to Maintain Sustainable Competitive Advantages-----Case Study on the Evolution of Organizational Strategic Management

    OpenAIRE

    2012-01-01

    The aim of the article is to analyze why the sustainable competitive advantage may disappear for many business organizations, and how to maintain the advantages in order to survive in the market. The paper proposes an evolution path of strategic literature, from the classical Porter¡¯s strategic theory to business inertia, strategic resilience, then Organizational transformation, finally to the Business sustainability. Based on the case studies and literature review, this paper makes a conclu...

  3. Maintaining Soft Arc Consistency in BnB-ADOPT+ During Search

    OpenAIRE

    Gutierrez, Patricia; Lee, Jimmy; Lei, Ka Man; Mak, Terrence W. K.; Meseguer, Pedro

    2013-01-01

    Gutierrez and Meseguer show how to enforce consistency in BnB-ADOPT + for distributed constraint optimization, but they consider unconditional deletions only. However, during search, more values can be pruned conditionally according to variable instantiations that define subproblems. Enforcing consistency in these subproblems can cause further search space reduction. We introduce efficient methods to maintain soft arc consistencies in every subproblem during search, a non trivial task due to ...

  4. A new era of prosperity through power : maintaining BC's competitive advantage

    International Nuclear Information System (INIS)

    The availability of abundant low cost electric power has been a driving force behind British Columbia's economic growth. BC's low cost power resources can create a natural competitive economic advantage for the province. Electricity, as a publicly owned resource can offer many competitive advantages for business in British Columbia, if managed correctly. However, it was noted that meaningful economic advantages can only be realized if the existing power resources in the province are operated efficiently and priced at or close to cost. In the 1980s, the Joint Industry Electricity Steering Committee (JIESC) was formed following the regulation of BC Hydro by BC Utilities Commission. It became clear that maintaining low rates for electricity was a public issue that needed input from other governmental forums if JIESC was to be successful. The major sectors represented by JIESC include pulp and paper, mining, and electrochemicals. This paper listed each member company. In order to turn BC's economy around and re-establish the province as a leading economy in Canada, the following recommendations have been proposed for the short term: (1) maintain an ample supply of low cost power for the future, (2) remove the provincial sales tax on the purchase of electric power used for manufacturing and processing, (3) extend the current rate freeze, (4) initiate a long-term resource acquisition and transmission expansion strategy to assure the availability of ample supplies of low cost power. Recommendations for the long term include: (1) maintain regulated cost based rates, (2) develop ample low cost power, (3) utilize downstream benefits, (4) provide a role for the private sector, (5) maintain adequate transmission facilities, (6) reduce government revenues, and (7) instill customer driven management. 3 figs

  5. Naturalness and Biodiversity: Why Natural Conditions Should Be Maintained Within Protected Areas

    OpenAIRE

    Steinhoff, Gordon

    2012-01-01

    In this Article, I will argue that naturalness (natural conditions) should be maintained as a mandatory goal in the management of protected areas. It will be important to describe in detail what naturalness as a management goal consists of. Within Beyond Naturalness, Cole, Yung, and other authors misrepresent the naturalness mandated within protected area law and policy. I wish to defend the claim that naturalness, properly understood, is necessary for the preservation of native biodiversi...

  6. Choices between positive and negative reinforcement during treatment for escape-maintained behavior.

    OpenAIRE

    DeLeon, I G; Neidert, P L; Anders, B M; Rodriguez-Catter, V

    2001-01-01

    Positive reinforcement was more effective than negative reinforcement in promoting compliance and reducing escape-maintained problem behavior for a child with autism. Escape extinction was then added while the child was given a choice between positive or negative reinforcement for compliance and the reinforcement schedule was thinned. When the reinforcement requirement reached 10 consecutive tasks, the treatment effects became inconsistent and reinforcer selection shifted from a strong prefer...

  7. Marketing and PR in Social Media : How the utilization of Instagram builds and maintains customer relationships

    OpenAIRE

    Bergström, Thamwika; Bäckman, Lisa

    2013-01-01

    With the rise of social media and the emergence of smartphones, new possibilities have arisen for companies to create and maintain customer relations. Today, customers expect companies to be represented on social media platforms. Customers today will discuss companies and products on social media, regardless of whether the companies are represented on the platforms or not. Therefore, it is important for companies to be present on these platforms in order to be a part of the discussion. On Ins...

  8. On Implementing Clinical Decision Support: Achieving Scalability and Maintainability by Combining Business Rules and Ontologies.

    OpenAIRE

    Kashyap, Vipul; Morales, Alfredo; Hongsermeier, Tonya

    2006-01-01

    We present an approach and architecture for implementing scalable and maintainable clinical decision support at the Partners HealthCare System. The architecture integrates a business rules engine that executes declarative if-then rules stored in a rule-base referencing objects and methods in a business object model. The rules engine executes object methods by invoking services implemented on the clinical data repository. Specialized inferences that support classification of data and instances...

  9. Rif1 Maintains Telomere Length Homeostasis of ESCs by Mediating Heterochromatin Silencing

    OpenAIRE

    Dan, Jiameng; Liu, Yifei; Liu, Na; Chiourea, Maria; Okuka, Maja; Wu, Tao; Ye, Xiaoying; Mou, Chunlin; Wang, Lei; Wang, Lingling; Yin, Yu; Yuan, Jihong; Zuo, Bingfeng; Wang, Fang; Li, Zhiguo

    2014-01-01

    Telomere length homeostasis is essential for genomic stability and unlimited self-renewal of embryonic stem cells (ESCs). We show that telomere-associated protein Rif1 is required to maintain telomere length homeostasis by negatively regulating Zscan4 expression, a critical factor for telomere elongation by recombination. Depletion of Rif1 results in terminal hyperrecombination, telomere length heterogeneity, and chromosomal fusions. Reduction of Zscan4 by shRNA significantly rescues telomere...

  10. Space Maintenance with an Innovative “Tube and Loop” Space Maintainer (Nikhil Appliance)

    Science.gov (United States)

    Grover, Jyotika; Panthri, Prerna

    2016-01-01

    ABSTRACT Despite the best efforts in prevention, premature loss of primary teeth continues to be a common problem in pediatric dentistry, resulting in disruption of arch integrity and adversely affecting the proper alignment of permanent successors. Space maintainers (SMs) are special appliances used for maintaining space created due to premature loss of primary teeth. Band and loop SM is mostly indicated for the premature loss of single primary molar, but this appliance has a number of limitations both for operators and for patients. Presented in this article is an innovative “Tube and Loop” SM (Nikhil appliance) which offers several advantages over the conventional band and loop SM. It is not only easy and quick to fabricate but can also be completed in a single sitting and cumbersome steps like impression making and laboratory procedures namely soldering are eliminated. How to cite this article: Srivastava N, Grover J, Panthri P. Space Maintenance with an Innovative “Tube and Loop” Space Maintainer (Nikhil Appliance). Int J Clin Pediatr Dent 2016;9(1):86-89. PMID:27274163

  11. Biodegradation of nickel and chromium from space maintainers: An in vitro study

    Directory of Open Access Journals (Sweden)

    Bhaskar V

    2010-03-01

    Full Text Available Band materials are often used in the practice of pediatric dentistry. Nickel and Chromium are the main ingredients of these materials. The potential health hazards of nickel and chromium and their compounds have been the focus of attention for more than 100 years. It has established that these metals could cause hypersensitivity. The study was undertaken to analyze in vitro biodegradation of space maintainers made out of stainless steel band materials from manufacturers Dentaurum and Unitek. The leaching effect simulating the use of one, two, three, and four space maintainers in clinical practice was studied by keeping the respective number of space maintainers in the artificial saliva incubating at 37°C and analyzing for nickel and chromium release after 1,7,14,21 and 28 days using atomic absorption spectrophotometer. Results showed that there was measurable release of both nickel and chromium which reached maximum level at the end of 7 days which was statistically significant (P < 0.05 and was very much below the dietary average intake even for four bands used and was not capable of causing any toxicity.

  12. Estimation of suitable flow needs for maintaining fish habitat conditions using water quantity and quality simulation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kyu-Ho [Korea Institute of Construction Technology, Koyang (Korea); Cho, Won-cheol [Yonsei University, Seoul (Korea); Jun, Byong-Ho [Korea Military Academy, Seoul (Korea)

    2000-02-29

    The primary objective of this study is to estimate the suitable flow in need for conservation and restoration of the fish habitat in running water ecosystem, which has very important status in the instream flow for stream environment. Year, monthly low flows are estimated to properly maintain the fish habitat. Water depth and velocity are simulated, and also water temperature and Dissolved Oxygen(DO) are predicted at gradually varied flow using estimated low flows. These simulated conditions for each low flow are graphically compared with the requirements to maintain fish habitat at each life stage. These processes were applied to 3 riffle transect located at Dalcheon(Dal stream) in the South Han river. Pirami (Zacco platypus) was selected as a representative fish species in Dalcheon. It was shown that the suitable flow for maintaining the representative fish habitat at each life stage depends on hydraulic conditions rather than water quality conditions, and the flow ranges from the 10-year minimum low flow to consecutive 7-day 2.33-year low flow. (author). 17 refs., 6 tabs., 4 figs.

  13. New method in information processing for maintaining an efficient dynamic ordered set

    Institute of Scientific and Technical Information of China (English)

    XIN ShiQing; WANG GuoJin

    2009-01-01

    This paper Investigates how to maintain an efficient dynamic ordered set of bit strings, which is an Important problem in the field of information search and information processing. Generally, a dynamic ordered set is required to support 5 essential operations including search, Insertion, deletion, max-value retrieval and next-larger-value retrieval. Based on previous research fruits, we present an advanced data structure named rich binary tree (RBT), which follows both the binary-search-tree property and the digital-search-tree property. Also, every key K keeps the most significant difference bit (MSDB) between itself and the next larger value among K's ancestors, as well as that between itself and the next smaller one among its ancestors. With the new data structure, we can maintain a dynamic ordered set in O(L) time. Since computers represent objects in binary mode, our method has a big potential in application. In fact, RBT can be viewed as a general-purpose data structure for problems concerning order, such as search, sorting and maintaining a priority queue. For example, when RBT is applied in sorting, we get a linear-time algorithm with regard to the key number and its performance is far better than quick-sort. What is more powerful than quick-sort is that RBT supports constant-time dynamic insertion/deletion.

  14. Maintaining communication link based on AODV routing protocol in mobile robot networks

    Science.gov (United States)

    Hu, Hui; Jiang, Hong

    2007-12-01

    Wired computer networks are vital in modern life. However, these networks are extremely vulnerable to disaster or attack in emergency situations. Therefore, how to maintain communication link under emergency situations is very important. In this paper, we utilize a series of autonomous mobile slave robots which follow behind the lead robot and automatically stop where needed to maintain an ad hoc network for guaranteeing a link between the lead robot and its remote monitor/control station. To accomplish this target, an efficient communication protocol limitation mobile robots broadcast based on AODV (LMRB-AODV) is proposed for deployment in multi-robot system. After then the lead robot could carry service traffics to the monitor station under emergency situations through the communication link. At any instance, the lead robot has the ability to reclaim the relay robot(s) which are unneeded in the network to rejoin the convoy behind the lead robot and use it to extend the range of wireless communication when the radio frequency (RF) shortcuts are detected by the lead robot. All relay deployment and reclaiming strategy functions occur without the operator's involvement. Finally, we provide a comparative study of their performance in a number of different simulation environments. The results show that the proposed scheme is very efficient in maintaining communication link in wireless network.

  15. Reduced reactivation from dormancy but maintained lineage choice of human mesenchymal stem cells with donor age.

    Directory of Open Access Journals (Sweden)

    Verena Dexheimer

    Full Text Available UNLABELLED: Mesenchymal stem cells (MSC are promising for cell-based regeneration therapies but up to date it is still controversial whether their function is maintained throughout ageing. Aim of this study was to address whether frequency, activation in vitro, replicative function, and in vitro lineage choice of MSC is maintained throughout ageing to answer the question whether MSC-based regeneration strategies should be restricted to younger individuals. MSC from bone marrow aspirates of 28 donors (5-80 years were characterized regarding colony-forming unit-fibroblast (CFU-F numbers, single cell cloning efficiency (SSCE, osteogenic, adipogenic and chondrogenic differentiation capacity in vitro. Alkaline phosphatase (ALP activity, mineralization, Oil Red O content, proteoglycan- and collagen type II deposition were quantified. While CFU-F frequency was maintained, SSCE and early proliferation rate decreased significantly with advanced donor age. MSC with higher proliferation rate before start of induction showed stronger osteogenic, adipogenic and chondrogenic differentiation. MSC with high osteogenic capacity underwent better chondrogenesis and showed a trend to better adipogenesis. Lineage choice was, however, unaltered with age. CONCLUSION: Ageing influenced activation from dormancy and replicative function of MSC in a way that it may be more demanding to mobilize MSC to fast cell growth at advanced age. Since fast proliferation came along with high multilineage capacity, the proliferation status of expanded MSC rather than donor age may provide an argument to restrict MSC-based therapies to certain individuals.

  16. Successfully maintaining program funding during trying times: lessons from tobacco control programs in five states.

    Science.gov (United States)

    Nelson, David E; Reynolds, Jennifer H; Luke, Douglas A; Mueller, Nancy B; Eischen, Monica H; Jordan, Jerelyn; Lancaster, R Brick; Marcus, Stephen E; Vallone, Donna

    2007-01-01

    Despite negative financial conditions in recent years, several states were able to successfully maintain funding for tobacco prevention and control, which provided an opportunity to understand the factors associated with success. One explanation may be the level of long-term program sustainability in some states. According to a model developed by Saint Louis University researchers, the five elements critical to tobacco control sustainability are state political and financial climate; community awareness and capacity; program structure and administration; funding stability and planning; and surveillance and evaluation. Five states (Nebraska, New York, Indiana, Virginia, and Colorado) maintained funding for their tobacco control programs. Four of these states gained additional legislative appropriations or prevented a massive reduction; Colorado used a statewide ballot initiative to increase funding. On the basis of the sustainability framework, case studies, and prior research, the major lessons learned for maintaining funding were the importance of (1) strong and experienced leadership, (2) broad and deep organizational and community ties, (3) coordinated efforts, (4) strategic use of surveillance and evaluation data, (5) active dissemination of information about program successes, and (6) policy maker champions. The sustainability framework and lessons learned may provide valuable insights for other public health programs facing funding threats. PMID:17984716

  17. An Evaluation of Maintainability of Aspect-Oriented Systems: a Practical Approach

    Directory of Open Access Journals (Sweden)

    Avadhesh Kumar

    2007-06-01

    Full Text Available Maintenance of software systems is becoming major concern for software developers and users. In software projects/products, where software changes/updates are frequently required to improve software quality, maintainability is an important characteristic of ISO 9126 quality standard to evaluate. Analyzability, changeability, stability, and testability are sub attributes/characteristics of maintainability in ISO 9126. In this paper, changeability is measured by making changes at code level of an Aspect- Oriented (AO system. The approach taken to evaluate the changeability of an AO system is to compute the impact of changes made to modules of the system. Some projects1 in aspect-oriented programming (AOP language, AspectJ, have been taken for testing. The results suggest that the AO system can easily absorb changes and AO design metrics can be used as indicators of changeability as well as of maintainability. The results also suggest that a code level change in AO systems not always cause less change impact to other modules than a code level change in Object-Oriented (OO systems.

  18. CrxOS maintains the self-renewal capacity of murine embryonic stem cells

    International Nuclear Information System (INIS)

    Embryonic stem (ES) cells maintain pluripotency by self-renewal. Several homeoproteins, including Oct3/4 and Nanog, are known to be key factors in maintaining the self-renewal capacity of ES cells. However, other genes required for the mechanisms underlying this process are still unclear. Here we report the identification by in silico analysis of a homeobox-containing gene, CrxOS, that is specifically expressed in murine ES cells and is essential for their self-renewal. ES cells mainly express the short isoform of endogenous CrxOS. Using a polyoma-based episomal expression system, we demonstrate that overexpression of the CrxOS short isoform is sufficient for maintaining the undifferentiated morphology of ES cells and stimulating their proliferation. Finally, using RNA interference, we show that CrxOS is essential for the self-renewal of ES cells, and provisionally identify foxD3 as a downstream target gene of CrxOS. To our knowledge, ours is the first delineation of the physiological role of CrxOS in ES cells.

  19. Does Genetic Variation Maintained by Environmental Heterogeneity Facilitate Adaptation to Novel Selection?

    Science.gov (United States)

    Huang, Yuheng; Tran, Ivan; Agrawal, Aneil F

    2016-07-01

    Environmental heterogeneity helps maintain genetic variation in fitness. Therefore, one might predict that populations living in heterogeneous environments have higher adaptive potential than populations living in homogeneous environments. Such a prediction could be useful in guiding conservation priorities without requiring detailed genetic studies. However, this prediction will be true only if the additional genetic variation maintained by environmental heterogeneity can be used to respond to novel selection. Here we examine the effect of environmental heterogeneity on future adaptability using replicated experimental Drosophila melanogaster populations that had previously evolved for ∼100 generations under one of four selective regimes: constant salt-enriched larvae medium, constant cadmium-enriched larvae medium, and two heterogeneous regimes that vary either temporally or spatially between the two media. Replicates of these experimental populations were subjected to a novel heat stress while being maintained in their original larval diet selection regimes. Adaptation to increased temperature was measured with respect to female productivity and male siring success after ∼20 generations. For female productivity, there was evidence of adaptation overall and heterogeneous populations had a larger adaptive response than homogeneous populations. There was less evidence of adaptation overall for male siring success and no support for faster adaptation in heterogeneous populations. PMID:27322119

  20. Energy Management: An Important Component of Quality Control in School Food Service.

    Science.gov (United States)

    Manning, Peter B.

    1984-01-01

    The cost of energy will continue to rise. Energy conservation, by reducing usage, will at least maintain energy costs. Energy management is an important part of the school food service manager's job. Guidelines are provided. (MLF)

  1. International energy efficiency and renewable energy resources on the Internet

    Energy Technology Data Exchange (ETDEWEB)

    Brown, M.A. [Oak Ridge National Lab., TN (United States); Meyer, R.D. [USDOE, Washington, DC (United States)

    1996-10-01

    A variety of sources of information on energy efficiency and renewable energy technologies are available on the Internet`s World Wide Web. These resources are sponsored and maintained by a myriad of organizations across the country and world. One expeditious way to access these resources is by using the U.S. Department of Energy`s Energy Efficiency and Renewable Energy Network (EREN). This network is a user-friendly computer link to Internet based information on energy conservation and renewable energy technologies and techniques. Numerous international sources of information can be accessed through EREN including the International Energy Agency`s Centre for the Analysis and Dissemination of Demonstrated Energy Technologies (CADDET) and the Greenhouse Gas Technology Information Exchange (GREENTIE). CADDET`s Register of demonstrated energy technologies provides an extensive guide to energy efficient and renewable energy technologies, and GREENTIE`s Directory of supplier information helps users access technology providers and experts.

  2. Exercise and the regulation of energy intake

    NARCIS (Netherlands)

    Scheurink, AJW; Ammar, AA; Benthem, B; van Dijk, G; Sodersten, PAT; Södersten, Per A.T.

    1999-01-01

    Energy balance is the resultant of ingested calories and energy expenditure and is generally maintained within narrow limits over prolonged periods. Exercise leads to an increase in energy expenditure which is, in the long-term, counteracted by increased energy intake. Evidence for this comes from a

  3. Maintaining knowledge, training and infrastructure for research and development in nuclear safety - INSAG-16. A report by the International Nuclear Safety Advisory Group

    International Nuclear Information System (INIS)

    . Education in nuclear science and technology needs to be stabilized in order to maintain sufficient human resources in sciences and engineering relating to nuclear safety. Part of the research infrastructure should be maintained at universities. There is a concern that deterioration of the research infrastructure may lead over time to a deterioration in safety which the public will not tolerate. National and international bodies have a key role to play in ensuring that the skills and capabilities required by the nuclear industry and its regulators are available and that the infrastructure required for this is provided for. Maintaining the safety of nuclear facilities, a pool of expertise and the level of safety research is a common concern of IAEA Member States and therefore, to the extent practicable, research facilities and research data should be shared in joint research programmes by IAEA Member States. The OECD Nuclear Energy Agency (OECD/NEA) is actively engaged in this effort. It has recently published two important reports dealing with research capabilities and facilities and with major research programmes at risk. Following up on the conclusions of these reports, the OECD/NEA continues to review safety research needs and organizes and sponsors internationally funded projects which contribute to maintaining key research facilities and teams. However, it is important that such efforts encompass all countries having nuclear power programmes. The IAEA and OECD/NEA could explore this possibility further. More frequent interactions among research managers in Member States should be considered to ensure that full advantage is being taken of the joint expertise and equipment available around the world. Results of national research programmes should be made public and broadly shared. This will increase public confidence and help to ensure that regulatory processes reflect the state of knowledge

  4. Maintaining knowledge, training and infrastructure for research and development in nuclear safety. INSAG-16. A report by the International Nuclear Safety Advisory Group (Russian Edition)

    International Nuclear Information System (INIS)

    . Education in nuclear science and technology needs to be stabilized in order to maintain sufficient human resources in sciences and engineering relating to nuclear safety. Part of the research infrastructure should be maintained at universities. There is a concern that deterioration of the research infrastructure may lead over time to a deterioration in safety which the public will not tolerate. National and international bodies have a key role to play in ensuring that the skills and capabilities required by the nuclear industry and its regulators are available and that the infrastructure required for this is provided for. Maintaining the safety of nuclear facilities, a pool of expertise and the level of safety research is a common concern of IAEA Member States and therefore, to the extent practicable, research facilities and research data should be shared in joint research programmes by IAEA Member States. The OECD Nuclear Energy Agency (OECD/NEA) is actively engaged in this effort. It has recently published two important reports dealing with research capabilities and facilities and with major research programmes at risk. Following up on the conclusions of these reports, the OECD/NEA continues to review safety research needs and organizes and sponsors internationally funded projects which contribute to maintaining key research facilities and teams. However, it is important that such efforts encompass all countries having nuclear power programmes. The IAEA and OECD/NEA could explore this possibility further. More frequent interactions among research managers in Member States should be considered to ensure that full advantage is being taken of the joint expertise and equipment available around the world. Results of national research programmes should be made public and broadly shared. This will increase public confidence and help to ensure that regulatory processes reflect the state of knowledge

  5. State energy data report 1995 - consumption estimates

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    The State Energy Data Report (SEDR) provides annual time series estimates of State-level energy consumption by major economic sectors. The estimates are developed in the State Energy Data System (SEDS), which is maintained and operated by the Energy Information Administration (EIA). The goal in maintaining SEDS exists for two principal reasons: (1) to provide State energy consumption estimates to Members of Congress, Federal and State agencies, and the general public, and (2) to provide the historical series necessary for EIA`s energy models.

  6. Maintaining competence in radiological protection in emergency situations - a challenge for the 21st century

    International Nuclear Information System (INIS)

    Full text: State of the art radiological protection in emergency situations requires specific resources and competence in a variety of scientific and technical areas. These include e.g. nuclear and reactor physics, metrology, health sciences, radiobiology, food production, waste management, and information technology. In many of these areas a high technical standard is currently available. This standard is based on great efforts of governments, universities/research institutions and the nuclear industry during the second half of the 20th century. Although the number of scientists and technicians in these areas may appear to be sufficient today at least in some countries, there are strong indicators that future expertise is at risk. The indicators are declining university enrolment, dilution of university course content, high retirement expectations of staff members with little or no replacement planned. During the last decade many international organizations have analyzed the current situation and identified risk areas. Many proposals of general nature are available to take appropriate steps to maintain competence in the 21st century. These proposals include the following recommendations for governments, for the industry, and for international and supra-national organisations. Governments are encouraged to engage in long term strategic planning and funding to maintain competence; organize networks of collaboration between specialised organisations to maintain critical groups size; take responsibility for ensuring that human resources are available to meet obligations; support 'educational networks' among universities, research institutions, and the industry; provide scholarships, fellowships, and traineeships as part of their funding policy. The industry is encouraged to maintain high level training and in house education to meet their specific needs; develop research programmes which are attractive for students and employees; improve co-operation with universities

  7. A Vision of the Journey Ahead: Using Public Health Notifiable Condition Mapping to Illustrate the Need to Maintain Value Sets

    OpenAIRE

    Grannis, Shaun; Vreeman, Daniel

    2010-01-01

    Maintaining value sets is a necessary and distinct activity apart from maintaining recognized controlled vocabularies. As an illustration of one such value set, we evaluate the CDC and Regenstrief versions of the notifiable condition mapping tables (NCMT) and illustrate they are not synchronized. We used practical informatics approaches including heuristic queries and similarity measures to accurately identify more than 800 new candidate reportable LOINC codes. To successfully maintain value ...

  8. Maintaining quality of health services after abolition of user fees: A Uganda case study

    Directory of Open Access Journals (Sweden)

    Okuonzi Sam A

    2008-05-01

    Full Text Available Abstract Background It has been argued that quality improvements that result from user charges reduce their negative impact on utilization especially of the poor. In Uganda, because there was no concrete evidence for improvements in quality of care following the introduction of user charges, the government abolished user fees in all public health units on 1st March 2001. This gave us the opportunity to prospectively study how different aspects of quality of care change, as a country changes its health financing options from user charges to free services, in a developing country setting. The outcome of the study may then provide insights into policy actions to maintain quality of care following removal of user fees. Methods A population cohort and representative health facilities were studied longitudinally over 3 years after the abolition of user fees. Quantitative and qualitative methods were used to obtain data. Parameters evaluated in relation to quality of care included availability of drugs and supplies and; health worker variables. Results Different quality variables assessed showed that interventions that were put in place were able to maintain, or improve the technical quality of services. There were significant increases in utilization of services, average drug quantities and stock out days improved, and communities reported health workers to be hardworking, good and dedicated to their work to mention but a few. Communities were more appreciative of the services, though expectations were lower. However, health workers felt they were not adequately motivated given the increased workload. Conclusion The levels of technical quality of care attained in a system with user fees can be maintained, or even improved without the fees through adoption of basic, sustainable system modifications that are within the reach of developing countries. However, a trade-off between residual perceptions of reduced service quality, and the welfare gains from

  9. Nrf2 is required to maintain the self-renewal of glioma stem cells

    International Nuclear Information System (INIS)

    Glioblastomas are deadly cancers that display a functional cellular hierarchy maintained by self-renewing glioma stem cells (GSCs). Self-renewal is a complex biological process necessary for maintaining the glioma stem cells. Nuclear factor rythroid 2-related factor 2(Nrf2) plays a significant role in protecting cells from endogenous and exogenous stresses. Nrf2 is a key nuclear transcription factor that regulates antioxidant response element (ARE)-containing genes. Previous studies have demonstrated the significant role of Nrf2 in the proliferation of glioblastoma, and in their resistance to radioactive therapies. We examined the effect of knocking down Nrf2 in GSCs. Nrf2 expression was down-regulated by shRNA transinfected with lentivirus. Expression levels of Nestin, Nrf2, BMI-1, Sox2 and Cyclin E were assessed by western blotting, quantitative polymerase chain reaction (qPCR) and immunohistochemistry analysis. The capacity for self-renewal in vitro was assessed by genesis of colonies. The capacity for self-renewal in vivo was analyzed by tumor genesis of xenografts in nude mice. Knockdown of Nrf2 inhibited the proliferation of GSCs, and significantly reduced the expression of BMI-1, Sox2 and CyclinE. Knocking down of Nrf2 changed the cell cycle distribution of GSCs by causing an uncharacteristic increase in the proportion of cells in the G2 phase and a decrease in the proportion of cells in the S phase of the cell cycle. Nrf2 is required to maintain the self-renewal of GSCs, and its down-regulation can attenuate the self-renewal of GSCs significantly

  10. Does maintaining a bottle of adhesive without the lid significantly reduce the solvent content?

    Science.gov (United States)

    Santana, Márcia Luciana Carregosa; Sousa Júnior, José Aginaldo de; Leal, Pollyana Caldeira; Faria-e-Silva, André Luis

    2014-01-01

    This study aimed to evaluate the effect of maintaining a bottle of adhesive without its lid on the solvent loss of the etch-and-rinse adhesive systems. Three 2-step etch-and-rinse adhesives with different solvents (acetone, ethanol or butanol) were used in this study. Drops of each adhesive were placed on an analytical balance and the adhesive mass was recorded until equilibrium was achieved (no significant mass alteration within time). The solvent content of each adhesive and evaporation rate of solvents were measured (n=3). Two bottles of each adhesive were weighted. The bottles were maintained without their lids for 8 h in a stove at 37 ºC, after which the mass loss was measured. Based on mass alteration of drops, acetone-based adhesive showed the highest solvent content (46.5%, CI 95%: 35.8-54.7) and evaporation rate (1.11 %/s, CI95%: 0.63-1.60), whereas ethanol-based adhesive had the lowest values (10.1%, CI95%: 4.3-16.0; 0.03 %/s CI95%: 0.01-0.05). However, none of the adhesives bottles exhibited significant mass loss after sitting for 8 h without their lids (% from initial content; acetone - 96.5, CI 95%: 91.8-101.5; ethanol - 99.4, CI 95%: 98.4-100.4; and butanol - 99.3, CI 95%: 98.1-100.5). In conclusion, maintaining the adhesive bottle without lid did not induce significant solvent loss, irrespective the concentration and evaporation rate of solvent. PMID:25590203

  11. Another transition in energy

    International Nuclear Information System (INIS)

    Turmoil in macro-energy is occurring along with institutional changes that the French do not always unanimously follow. Habituated to the French public service model, which has maintained a fair level of prices and a constant supply of energy insofar as possible, the French are discovering a complex system that hinges ever more on services rather than prices: the culture of competition, complementarity and service. We must learn to sell and not just produce, to accept newcomers and become flexible. (author)

  12. Thermionic photovoltaic energy converter

    Science.gov (United States)

    Chubb, D. L. (Inventor)

    1985-01-01

    A thermionic photovoltaic energy conversion device comprises a thermionic diode mounted within a hollow tubular photovoltaic converter. The thermionic diode maintains a cesium discharge for producing excited atoms that emit line radiation in the wavelength region of 850 nm to 890 nm. The photovoltaic converter is a silicon or gallium arsenide photovoltaic cell having bandgap energies in this same wavelength region for optimum cell efficiency.

  13. Free birds aren't fat: Weight gain in captured wild pigeons maintained under laboratory conditions

    OpenAIRE

    Poling, Alan; Nickel, Mark; Alling, Ken

    1990-01-01

    Nine feral pigeons, 5 from an urban setting and 4 from a rural setting, were captured and maintained for 42 days under free-feeding conditions comparable to those arranged for laboratory subjects. On average, birds increased their body weights by 17% over this period. The range of increase across birds was 9 to 30%. These findings suggest that the food deprivation arranged for laboratory pigeons, which is characteristically 80% of free-feeding weights, may in some sense be less severe than it...

  14. The impact of repeat stereotactic radiosurgery on the management of brain metastasis with maintaining brain function

    International Nuclear Information System (INIS)

    We investigated the utility of repeat stereotactic radiosurgery (RSRS), assisted with a careful monitoring by MRI, in the management of brain metastases. Thirty-seven patients harboring brain metastasis received RSRS. RSRS at the same site was performed in 14. The cumulative 5-year survival rate was 29% and the median survival time was 32 months. Cause of death was as follows: 14 uncontrolled extracranial disease and 2 progressed brain metastases. There were no severe adverse events. For 16 patients, neurocognitive function was examined and the most recent results revealed that 88% was not associated with impaired neurocognition. RSRS appears a preferred option to manage brain metastases with maintaining brain function. (author)

  15. Intraspecific variation in avian pectoral muscle mass: constraints on maintaining manoeuvrability with increasing body mass

    OpenAIRE

    Dietz, Maurine W.; Piersma, Theunis; Hedenstrom, Anders; Brugge, Maarten; Hedenström, Anders; Jackson, Sue

    2007-01-01

    1. Within a single year, long-distance migrants undergo a minimum of four cycles of fuel storage and depletion because their migrations have at least one stopover. Each cycle includes an almost twofold change in body mass (m(b)). Pervasive predation threats beg the question whether escape flight abilities keep up with such large changes in m(b). 2. We derive aerodynamic predictions how pectoral muscle mass (m(pm)) should change with m(b) to maintain constant relative flight power. 3. We teste...

  16. Birefringence properties of a polarization maintaining Panda fibre during Bragg grating regeneration

    Science.gov (United States)

    Polz, Leonhard; Jarsen, Andreas; Bartelt, Hartmut; Roths, Johannes

    2015-09-01

    Regeneration of fibre Bragg gratings under application of a high temperature annealing process in a high birefringent polarisation maintaining fibre of type Panda was investigated. During the annealing process, a distinct nonlinearity and hysteresis of the birefringence with temperature was observed. After the temperature process, the birefringence between slow and fast axis at room temperature was nearly doubled, which is in agreement with observations of other researchers. The hysteresis in birefringence might be explained by the crossing of the transition temperature of the stress applying parts and the relief of in-frozen mechanical and thermal stresses.

  17. Relegitimizing the medical profession: The role of opinion leaders in maintaining institutions through engaging with change

    OpenAIRE

    Simon Moralee

    2015-01-01

    This paper seeks to address how actors from an elite social position (known herein as ‘opinion leaders’) have engaged with change, which maintains the institution and relegitimizes its role. Situated in the case of the medical profession within the English National Health Service (NHS), this paper aims to explore and explain how individuals have taken the opportunity and advantage of a particular context, time and space in the NHS ‘story’, to practise, act and work to bring about change to m...

  18. Hanford Site guide for preparing and maintaining generator group pollution prevention program documentation

    International Nuclear Information System (INIS)

    This document provides guidance to generator groups for preparing and maintaining documentation of Pollution Prevention Waste Minimization (P2/WMin) Program activities. The guidance is one of a hierarchical series that includes the Hanford Site Waste Minimization and Pollution Prevention Awareness Program Plan (DOE-RL, 1998a) and Prime contractor implementation plans describing programs required by Resource Conservation and Recovery Act of 1976 (RCRA) 3002(b) and 3005(h) (RCRA and EPA, 1994). Documentation guidance for the following five P2/WMin elements are discussed: Fiscal Year (FY) Goals; Budget and Staffing; Waste Minimization (WMin) Assessments (WMAs); Quarterly Pollution Prevention (P2) Reporting WMin Certification

  19. Selective methods for the maintainability and standardization of the engineering of a research reactor

    International Nuclear Information System (INIS)

    the same function in each specialty. These diversities bring about conflicts and confusion between the maintenance and operation crew, besides modifying dangerously the fail rate and thus the overall reliability of the reactor. The maintainability is the capacity of being maintained an equipment/system has, serving as a design parameter. A system must be designed in a way in which it is maintained without a great investment of time and with low costs, minimum environmental impact and the least resources possible. Standardization is the action of normalizing the engineering of all systems/equipments of the reactor from its design, in all the disciplines, (mechanical, electrical, electronic, chemical, etc.) taking into consideration the facility of its maintenance and conserving or increasing the reliability of the system. The intention of this Program of Maintainability and Standardization in Research Reactors is based on procedures and calculations to improve the reliability of the equipments/systems according to pre-established criterion. (author)

  20. Cost-effectiveness of combustion turbines: recommendations for reliability, maintainability, supportability and maintenance requirements

    Energy Technology Data Exchange (ETDEWEB)

    Meuwisse, C.; Despujols, A. [Electricite de France, Research and Development Division, Chatou (France); Givaudan, B. [Electricite de France, Research and Development Division - SEPTEN, Villeurbanne (France); Lafage, L. [Electricite de France, Engineering and Construction Division - CNET, Paris (France)

    1998-12-31

    The profitability of combustion turbines intended for export is of extreme importance for Electricite de France. It is principally during the development phase of a project that one can ensure resect of two indissociable factors, essential to the per-kWh production cost: global operating costs and performance in terms of reliability and availability. The approach proposed here advocates the global acquisition of the installation and its logistic support. Generally applicable recommendations are given. They enable integrating in the future plant specifications all requirements relative to plant reliability, availability, maintainability and logistic support. They are structured according to type: expression of needs and management factors. (orig.) 4 refs.

  1. Maintaining and improving of the training program on the analysis software in CMS

    International Nuclear Information System (INIS)

    Since 2009, the CMS experiment at LHC has provided intensive training on the use of Physics Analysis Tools (PAT), a collection of common analysis tools designed to share expertise and maximize productivity in the physics analysis. More than ten one-week courses preceded by prerequisite studies have been organized and the feedback from the participants has been carefully analyzed. This note describes how the training team designs, maintains and improves the course contents based on the feedback, the evolving analysis practices and the software development.

  2. Widely tunable polarization maintaining photonic crystal fiber based parametric wavelength conversion.

    Science.gov (United States)

    Murray, Robert T; Kelleher, Edmund J R; Popov, Sergei V; Mussot, Arnaud; Kudlinski, Alexandre; Taylor, James R

    2013-07-01

    We report a near-visible parametric wavelength converter comprising a polarization-maintaining photonic crystal fiber (PM-PCF) pumped by a highly versatile diode-seeded master-oscillator power amplifier system based around 1.06 μm. The device is broadly tunable in wavelength (0.74-0.81 μm), pulse duration (0.2-1.5 ns) and repetition rate (1-30 MHz). A maximum anti-Stokes slope conversion efficiency of 14.9% is achieved with corresponding anti-Stokes average output powers of 845 mW, at a wavelength of 0.775 μm. PMID:23842368

  3. Hanford Site Guide for Preparing and Maintaining Fenerator Group Pollution Prevention Program Documentation

    International Nuclear Information System (INIS)

    This document provides guidance to generator groups for preparing and maintaining documentation of Pollution Prevention/Waste Minimization (P2/WMin) Program activities. The guidance is one of a hierarchical series that includes the Hanford Site Waste Minimization and Pollution Prevention Awareness Program Plan (DOE-RL, 1998a) and Prime Contractor implementation plans describing programs required by Resource Conservation and Recovery Act of 1976 (RCRA) 3002(b) and (300501) (RCRA and EPA, 1994). Documentation guidance for the following five P2/WMin elements are discussed: Fiscal Year (FY) Goals; Budget and Staffing; Waste Minimization (WMinn ) Assessments (WMAs); Pollution Prevention (P2) Reporting; WMin Certification

  4. The National Economy Maintained a Steady and Fast Growth in 2006

    Institute of Scientific and Technical Information of China (English)

    Xie Fuzhan

    2007-01-01

    @@ In 2006, the national economy maintained steady and fast growth.The Central Party Committee and the State Council adopted a series of macro-economic control policies and measures in a timely manner to target the outstanding problems,which emerged in economic development. These policies and measures proved to be effective and helped the economic development avoid moving from speedy growth to over-heating.The economic and social development made a good start for the implementation of the 11th Five-Year Plan.

  5. A New Brace for Maintaining the Neck in a Suitable Position Following Tracheal Reconstruction

    Directory of Open Access Journals (Sweden)

    Bizhan Ziaian

    2015-05-01

    Full Text Available Segmental resection and end-to-end anastomosis is the treatment of choice for patients suffering from tracheal stenosis for whom conservative management is not planned. A complication of this procedure is tension-induced anastomotic failure. To prevent this complication, maintaining the neck in full flexion by means of a suture between the chin and upper chest is a traditional approach. We have designed a new brace (Shiraz brace that securely supports the neck in this position and decreases the bothersome use of the suture alone.

  6. A new brace for maintaining the neck in a suitable position following tracheal reconstruction.

    Science.gov (United States)

    Ziaian, Bizhan; Foroutan, Ali; Tahamtan, Maryam; Moslemi, Sam

    2014-05-01

    Segmental resection and end-to-end anastomosis is the treatment of choice for patients suffering from tracheal stenosis for whom conservative management is not planned. A complication of this procedure is tension-induced anastomotic failure. To prevent this complication, maintaining the neck in full flexion by means of a suture between the chin and upper chest is a traditional approach. We have designed a new brace (Shiraz brace) that securely supports the neck in this position and decreases the bothersome use of the suture alone. PMID:24850991

  7. Impact of Magnet Culture in Maintaining Quality Outcomes During Periods of Organizational Transition.

    Science.gov (United States)

    Gonzalez, Judith F Zedreck; Wolf, Gail; Dudjak, Linda; Jordan, Bernadette

    2015-01-01

    Organizational transition presents substantial risk to maintaining quality outcomes. The leadership style and culture present during periods of change and transition empower the frontline staff to react quickly and identify opportunities. The culture of Magnet develops the skill set that enables staff to be leaders in problem solving and identifying creative care delivery approaches. Objectives of this study were to analyze the impact of organizational transition on patient and staff satisfaction, quality, and safety in a Magnet-designated hospital and determine key factors contributing to these outcomes. PMID:25768059

  8. Definition and means of maintaining the criticality detectors and alarms portion of the PFP safety envelope

    International Nuclear Information System (INIS)

    The Criticality Alarm System (CAS) provides continuous detection for high radiation (criticality) events and automatically initiates an evacuation signal to affected personnel. The Safety Envelope (SE) for PFP includes the necessary equipment and the required procedures to ensure the CAS is capable of performing its intended function. This document provides the definition and means of maintaining the SE for PFP related to the CAS. This document also identifies and provides a justification for those portions of the CAS excluded from the PFP Safety Envelope

  9. State Maintained Highways in Louisiana, UTM Zone 15 NAD83, LDOTD (2007) [state_highways_ldotd_2007

    Data.gov (United States)

    Louisiana Geographic Information Center — This dataset represents the state maintained road network of Louisiana. The dataset includes Interstates, US highways, and Louisiana State Highways. This dataset...

  10. Quantification of Hungry Horse Reservoir Water Levels Needed to Maintain or Enhance Reservoir Fisheries, 1985 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    May, Bruce

    1986-06-01

    The Pacific Northwest Electric Power Planning and Conservation Act, passed in 1980 by Congress, has provided a mechanism which integrates and provides for stable energy planning in the Pacific Northwest. The Act created the Northwest Power Planning Council and charged the Council with developing a comprehensive fish and wildlife program to protect and enhance fish and wildlife impacted by hydroelectric development in the Columbia River Basin. Bonneville Power Administration (BPA) is one of the many agencies implementing the Council's program. The Hungry Horse Reservoir (HHR) study is part of the Council's program. This study proposes to quantify seasonal water levels needed to maintain or enhance principal gamefish species in Hungry Horse Reservoir. The specific study objectives are: (1) Quantify the amount of reservoir habitat available at different water level elevations; (2) Estimate recruitment of westslope cutthroat trout juveniles from important spawning and nursery areas; (3) Determine the abundance, growth, distribution and use of available habitat by major game species in the reservoir; (4) Determine the abundance and availability of fish food organisms in the reservoir; (5) Quantify the seasonal use of available food items by major fish species; (6) Develop relationships between reservoir drawdown and reservoir habitat use by fish and fish food organisms; and (7) Estimate the impact of reservoir operation on major gamefish species.

  11. Quantification of Hungry Horse Reservoir Water Levels Needed to Maintain or Enhance Reservoir Fisheries, 1983-1985 Summary Report.

    Energy Technology Data Exchange (ETDEWEB)

    May, Bruce

    1985-06-01

    The Pacific Northwest Electric Power Planning and Conservation Act passed in 1980 by Congress has provided a mechanism which integrates and provides for stable energy planning in the Pacific Northwest. The Act created the Northwest Power Planning Council and charged the Council with developing a comprehensive fish and wildlife program to protect and enhance fish and wildlife impacted by hydroelectric development in the Columbia River Basin. Implementation of the plan is being carried out by the Bonneville Power Administration. The Hungry Horse Reservoir study is part of that Council's plan. This study proposes to quantify seasonal water levels needed to maintain or enhance principal gamefish species in Hungry Horse Reservoir. The specific study objects are listed below. (1) Quantify the amount of reservoir habitat available at different water level elevations; (2) Estimate recruitment of westslope cutthroat trout juveniles from important spawning and nursery tributaries; (3) Determine the abundance, growth, distribution and use of available habitat by major game species in the reservoir; (4) Determine the abundance and availability of fish food organisms in the reservoir; (5) Quantify the seasonal use of available food items by major fish species; (6) Develop relationships between reservoir drawdown and reservoir habitat used by fish and fish food organisms; and (7) Estimate the impact of reservoir operation on major gamefish species.

  12. Favorable climatic regime for maintaining the present-day geometry of the Gregoriev Glacier, Inner Tien Shan

    Directory of Open Access Journals (Sweden)

    K. Fujita

    2011-07-01

    Full Text Available We conducted 2 yr (2005–2007 of in situ meteorological and glaciological observations on the Gregoriev Glacier, a flat-top glacier within the Inner Tien Shan, Kyrgyzstan. Relative carrier-phase GPS surveys reveal a vertical lowering at the summit of the glacier. Based on snow density data and an energy-mass balance model, we estimate that the annual precipitation and summer mean temperature required to maintain the glacier in the current state are 289 mm and −3.8 °C at the glacier summit (4600 m a.s.l., respectively. The good agreement between dynamically derived precipitation and the long-term observed precipitation at a nearby station in the Tien Shan (296 mm at 3614 m a.s.l. for the period 1930–2002 suggests that the glacier has been in a near steady-state in terms of mass supply. The glacier mass-balance, reconstructed based on meteorological data from the Tien Shan station for the past 80 yr, explains the observed fluctuations in glacier extent, particularly the negative mass balance in the 1990s.

  13. Sward canopy structure and performance of beef heifers under supplementation in Brachiaria brizantha cv. Marandu pastures maintained with three grazing intensities in a continuous stocking system

    OpenAIRE

    Daniel Rume Casagrande; Ana Cláudia Ruggieri; Matheus Henrique Moretti; Telma Teresinha Berchielli; Bruno Ramalho Vieira; Anna Paula de Toledo Piza Roth; Ricardo Andrade Reis

    2011-01-01

    The objective of this study was to assess the sward canopy structure of Brachiaria brizantha cv. Marandu pastures maintained in three grazing intensities under continuous stocking system during the rainy season, along with the behavior and performance of grazing beef heifers supplemented with mineral salt or an energy/protein supplement. Three levels of forage allowance were assessed: 2.0, 2.5 and 3.0 kg of forage/kg of live weight, combined with two supplements (ad libitum mineral salt, and ...

  14. Isolated tumor endothelial cells maintain specific character during long-term culture

    International Nuclear Information System (INIS)

    Tumor angiogenesis is necessary for solid tumor progression and metastasis. Increasing evidence indicates that tumor endothelial cells (TECs) are more relevant to the study of tumor angiogenesis than normal endothelial cells (NECs) because their morphologies and gene expression are different from NECs. However, it is challenging to isolate and culture large numbers of pure ECs from tumor tissue since the percentage of ECs is only about 1-2% and tumor cells and fibroblasts easily overgrow them. In addition, there has been concern that isolated TECs may lose their special phenotype once they are dissociated from tumor cells. In this study, we have successfully purified murine TECs from four different human tumor xenografts and NECs from murine dermal tissue. Isolated ECs expressed endothelial markers, such as CD31, VE-cadherin (CD144), and endoglin (CD105), for more than 3 months after isolation. TECs maintained tumor endothelial-specific markers, such as tumor endothelial marker 8 (TEM8) and aminopeptidase N (APN), as in tumor blood vessels in vivo. In addition, TECs were more proliferative and motile than NECs. TECs showed a higher response to VEGF and higher expression of VEGF receptors-1 and -2 than NECs did. Stem cell antigen-1 was up-regulated in all four TECs, suggesting that they have a kind of stemness. Cultured TECs maintain distinct biological differences from NECs as in vivo. In conclusion, it was suggested that TECs are relevant material for tumor angiogenesis research.

  15. Maintaining Privacy in Pervasive Computing - Enabling Acceptance of Sensor-based Services

    Science.gov (United States)

    Soppera, A.; Burbridge, T.

    During the 1980s, Mark Weiser [1] predicted a world in which computing was so pervasive that devices embedded in the environment could sense their relationship to us and to each other. These tiny ubiquitous devices would continually feed information from the physical world into the information world. Twenty years ago, this vision was the exclusive territory of academic computer scientists and science fiction writers. Today this subject has become of interest to business, government, and society. Governmental authorities exercise their power through the networked environment. Credit card databases maintain our credit history and decide whether we are allowed to rent a house or obtain a loan. Mobile telephones can locate us in real time so that we do not miss calls. Within another 10 years, all sorts of devices will be connected through the network. Our fridge, our food, together with our health information, may all be networked for the purpose of maintaining diet and well-being. The Internet will move from being an infrastructure to connect computers, to being an infrastructure to connect everything [2, 3].

  16. A novel Snf2 protein maintains trans-generational regulatory states established by paramutation in maize.

    Directory of Open Access Journals (Sweden)

    Christopher J Hale

    2007-10-01

    Full Text Available Paramutations represent heritable epigenetic alterations that cause departures from Mendelian inheritance. While the mechanism responsible is largely unknown, recent results in both mouse and maize suggest paramutations are correlated with RNA molecules capable of affecting changes in gene expression patterns. In maize, multiple required to maintain repression (rmr loci stabilize these paramutant states. Here we show rmr1 encodes a novel Snf2 protein that affects both small RNA accumulation and cytosine methylation of a proximal transposon fragment at the Pl1-Rhoades allele. However, these cytosine methylation differences do not define the various epigenetic states associated with paramutations. Pedigree analyses also show RMR1 does not mediate the allelic interactions that typically establish paramutations. Strikingly, our mutant analyses show that Pl1-Rhoades RNA transcript levels are altered independently of transcription rates, implicating a post-transcriptional level of RMR1 action. These results suggest the RNA component of maize paramutation maintains small heterochromatic-like domains that can affect, via the activity of a Snf2 protein, the stability of nascent transcripts from adjacent genes by way of a cotranscriptional repression process. These findings highlight a mechanism by which alleles of endogenous loci can acquire novel expression patterns that are meiotically transmissible.

  17. Methyl Jasmonate Reduces Chilling Injury and Maintains Postharvest Quality in Peaches

    Institute of Scientific and Technical Information of China (English)

    FENG Lei; ZHENG Yong-hua; ZHANG Yan-fen; WANG Feng; ZHANG Lan; LU Zhao-xin

    2003-01-01

    Zhaohui peaches (Prunus persica Batsch) were treated with 0 (CK), 1, 10 or 100 μmol L-1methyl jasmonate (MeJA) vapor at 20℃ for 24 h before stored at 0℃ for 35 d. The untreated fruits showed chilling injury (CI) symptoms after 4 wk of storage, as indicated by increased fruit firmness and reduced extractable juice, which is referred as leatheriness. Treatment with 1 and 10 μmol L-1 MeJA promoted normal ripening and softening, maintained higher levels of extractable juice, titratable acidity, pectinesterase (PE)and polygalacturonase (PG) activities, inhibited increases in fruit fresh weight loss, decay incidence, electrolyte leakage and MDA content, and improved color development, thereby preventing chilling injury symptoms development and maintaining edible quality. MeJA treatment also delayed the climacteric rise in respiratory rate, but promoted ethylene production during the later period of cold storage, suggesting that ethylene may involve in CI development of peaches. These results indicate that 1 and 10 μmol L-1 MeJA treatments could be used to reduce CI development and decay incidence in peaches.

  18. The role of environmental insurance in maintaining environmental safety of the region

    Directory of Open Access Journals (Sweden)

    Svetlana Yevgenyevna Shipitsyna

    2013-03-01

    Full Text Available In the article, the development problems of environmental insurance as a risk management method for maintaining environmental safety in the region are considered. The detailed analysis of the laws of the Russian Federation in conservation activity is presented; contradictions and shortcomings arerevealed. Ways of overcoming of theexisting formalcharacter of maintaining environmental safety in the Russian regions are offered. In particular, extension of insurance covering in the current law «On compulsory insurance of the civil liability of an owner of dangerous installation on the infliction of harm as a result of accident on dangerous installation» at the expense of inclusion in number of insurance risks of risk of environmental harm. The special attention in the article is paid to insurance of public liability of owners of chemical objects as the most dangerous to the environment. The methodology of actuarial expectation is added with a risk assessment of expert services with the use of a scoring method allowing evaluating real danger to the population and the environment by the chemicals, which are especially acting in small doses. Furthermore, the added calculation methodology of insurance tariffs allows using preventive function of insurance, not so popular in Russian practices. That gives a new source of financing of nature-conservative measures in the region

  19. Roles of the creatine kinase system and myoglobin in maintaining energetic state in the working heart

    Directory of Open Access Journals (Sweden)

    Beard Daniel A

    2009-02-01

    Full Text Available Abstract Background The heart is capable of maintaining contractile function despite a transient decrease in blood flow and increase in cardiac ATP demand during systole. This study analyzes a previously developed model of cardiac energetics and oxygen transport to understand the roles of the creatine kinase system and myoglobin in maintaining the ATP hydrolysis potential during beat-to-beat transient changes in blood flow and ATP hydrolysis rate. Results The theoretical investigation demonstrates that elimination of myoglobin only slightly increases the predicted range of oscillation of cardiac oxygenation level during beat-to-beat transients in blood flow and ATP utilization. In silico elimination of myoglobin has almost no impact on the cytoplasmic ATP hydrolysis potential (ΔGATPase. In contrast, disabling the creatine kinase system results in considerable oscillations of cytoplasmic ADP and ATP levels and seriously deteriorates the stability of ΔGATPase in the beating heart. Conclusion The CK system stabilizes ΔGATPase by both buffering ATP and ADP concentrations and enhancing the feedback signal of inorganic phosphate in regulating mitochondrial oxidative phosphorylation.

  20. Seniors’ self-preservation by maintaining established self and defying deterioration – A grounded theory

    Directory of Open Access Journals (Sweden)

    Jeanette Källstrand Eriksson

    2016-05-01

    Full Text Available The purpose of this classic grounded theory study was to understand how seniors who are living independently resolve issues influenced by visual impairment and high fall risk. We interviewed and observed 13 seniors with visual impairment in their homes. We also interviewed six visual instructors with experience from many hundreds of relevant incidents from the same group of seniors. We found that the seniors are resolving their main concern of “remaining themselves as who they used to be” by self-preservation. Within this category, the strategies maintaining the established self and defying deterioration emerged as the most prominent in our data. The theme maintaining the established self is mostly guided by change inertia and includes living the past (retaining past activities, reminiscing, and keeping the home intact and facading (hiding impairment, leading to avoidance of becoming a burden and to risk juggling. Defying deterioration is a proactive scheme and involves moving (by exercising, adapting activities, using walking aids, driving, adapting (by finding new ways, and networking by sustaining old support networks or finding new networks. Self-preservation is generic human behavior and modifying this theory to other fields may therefore be worthwhile. In addition, health care providers may have use for the theory in fall preventive planning.