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Sample records for candidate xte j1720-318

  1. High-energy observations of the state transition of the X-ray nova and black hole candidate XTE J1720-318

    DEFF Research Database (Denmark)

    Bel, M.C.; Rodriguez, J.; Sizun, P.;

    2004-01-01

    We report the results of extensive high-energy observations of the X-ray transient and black hole candidate XTE J1720-318 performed with INTEGRAL, XMM-Newton and RXTE. The source, which underwent an X-ray outburst in 2003 January, was observed in February in a spectral state dominated by a soft c...

  2. X-Ray Bursts from the Transient Magnetar Candidate XTE J1810-197

    Science.gov (United States)

    Kouveliotou, Chryssa; Woods, Peter M.; Gavriil, Fotis P.; Kaspi, Victoria M.; Roberts, Mallory S. E.; Ibrahim, Alaa; Markwardt, Craig B.; Swank, Jean H.; Finger, Mark H.

    2005-01-01

    We have discovered four X-ray bursts, recorded with the Rossi X-ray Timing Explorer Proportional Counter Array between 2003 September and 2004 April, that we show to originate from the transient magnetar candidate XTE 51810-197. The burst morphologies consist of a short spike or multiple spikes lasting approx. 1 s each followed by extended tails of emission where the pulsed flux from XTE 51810-197 is significantly higher. The burst spikes are likely correlated with the pulse maxima, having a chance probability of a random phase distribution of 0.4%. The burst spectra are best fit to a blackbody with temperatures 4-8 keV, considerably harder than the persistent X-ray emission. During the X-ray tails following these bursts, the temperature rapidly cools as the flux declines, maintaining a constant emitting radius after the initial burst peak. The temporal and spectral characteristics of these bursts closely resemble the bursts seen from 1E 1048.1-5937 and a subset of the bursts detected from 1E 2259+586, thus establishing XTE J1810-197 as a magnetar candidate. The bursts detected from these three objects are sufficiently similar to one another, yet si,g&cantly differe2t from those seen from soft gamma repeaters, that they likely represent a new class of bursts from magnetar candidates exclusive (thus far) to the anomalous X-ray pulsar-like sources.

  3. Multiwavelength Observations of the Black Hole Candidate XTE J1550-564 during the 2000 Outburst

    Science.gov (United States)

    Jain, Raj K.; Bailyn, Charles D.; Orosz, Jerome A.; McClintock, Jeffrey E.; Remillard, Ronald A.

    2001-06-01

    We report optical, infrared, and X-ray light curves for the outburst, in 2000, of the black hole candidate XTE J1550-564. We find that the start of the outburst in the H and V bands precedes that seen in the Rossi X-Ray Timing Explorer All-Sky Monitor by 11.5+/-0.9 and 8.8+/-0.6 days, respectively; a similar delay has been observed in two other systems. About 50 days after the primary maxima in the VIH light curves, we find secondary maxima, most prominently in H. This secondary peak is absent in the X-ray light curve but coincides with a transition to the low/hard state. We suggest that this secondary peak may be due to nonthermal emission associated with the formation of a jet.

  4. Multiwavelength Observations of the Black Hole Candidate XTE J1550-564 during the 2000 Outburst

    CERN Document Server

    Jain, R K; Orosz, J A; McClintock, J E; Remillard, R A

    2001-01-01

    We report optical, infrared, and X-ray light curves for the outburst, in 2000, of the black hole candidate XTE J1550-564. We find that the start of the outburst in the H and V bands precedes that seen in the RXTE All Sky Monitor by 11.5 +/- 0.9 and 8.8 +/- 0.6 days, respectively; a similar delay has been observed in two other systems. About 50 days after the primary maxima in the VIH light curves, we find secondary maxima, most prominently in H. This secondary peak is absent in the X-ray light curve, but coincides with a transition to the low/hard state. We suggest that this secondary peak may be due to non-thermal emission associated with the formation of a jet.

  5. NuSTAR and SWIFT Observations of the Black Hole Candidate XTE J1908+094 during its 2013 Outburst

    DEFF Research Database (Denmark)

    Tao, Lian; Tomsick, John A.; Walton, Dominic J.;

    2015-01-01

    The black hole (BH) candidate XTE J1908+094 went into outburst for the first time since 2003 in 2013 October. We report on an observation with the Nuclear Spectroscopic Telescope Array (NuSTAR) and monitoring observations with Swift during the outburst. NuSTAR caught the source in the soft state:...

  6. NuSTAR and Swift observations of the black hole candidate XTE J1908+094 during its 2013 outburst

    CERN Document Server

    Tao, Lian; Walton, Dominic J; Furst, Felix; Kennea, Jamie; Miller, Jon M; Boggs, Steven E; Christensen, Finn E; Craig, William W; Gandhi, Poshak; Grefenstette, Brian W; Hailey, Charles J; Harrison, Fiona A; Krimm, Hans A; Pottschmidt, Katja; Stern, Daniel; Tendulkar, Shriharsh P; Zhang, William W

    2015-01-01

    The black hole candidate XTE J1908+094 went into outburst for the first time since 2003 in October 2013. We report on an observation with the Nuclear Spectroscopic Telescope Array (NuSTAR) and monitoring observations with Swift during the outburst. NuSTAR caught the source in the soft state: the spectra show a broad relativistic iron line, and the light curves reveal a ~40 ks flare with the count rate peaking about 40% above the non-flare level and with significant spectral variation. A model combining a multi-temperature thermal component, a power-law, and a reflection component with an iron line provides a good description of the NuSTAR spectrum. Although relativistic broadening of the iron line is observed, it is not possible to constrain the black hole spin with these data. The variability of the power-law component, which can also be modeled as a Comptonization component, is responsible for the flux and spectral change during the flare, suggesting that changes in the corona (or possibly continued jet act...

  7. A late jet rebrightening revealed from multiwavelength monitoring of the black hole candidate XTE J1752-223

    Science.gov (United States)

    Russell, D. M.; Curran, P. A.; Muñoz-Darias, T.; Lewis, F.; Motta, S.; Stiele, H.; Belloni, T.; Miller-Jones, J. C. A.; Jonker, P. G.; O'Brien, K.; Homan, J.; Casella, P.; Gandhi, P.; Soleri, P.; Markoff, S.; Maitra, D.; Gallo, E.; Cadolle Bel, M.

    2012-01-01

    We present optical monitoring of the black hole candidate XTE J1752-223 during its 2009-10 outburst and decay to quiescence. The optical light curve can be described by an exponential decay followed by a plateau, then a more rapid fade towards quiescence. The plateau appears to be due to an extra component of optical emission that brightens and then fades over ˜40 days. We show evidence for the origin of this optical 'flare' to be the synchrotron jet during the decaying hard state, and we identify and isolate both disc and jet components in the spectral energy distributions. The optical flare has the same morphology and amplitude as a contemporaneous X-ray rebrightening. This suggests a common origin, but no firm conclusions can be made favouring or disfavouring the jet producing the X-ray flare. The quiescent optical magnitudes are B≥ 20.6, V≥ 21.1, R≥ 19.5, i'≥ 19.2. From the optical outburst amplitude we estimate a likely orbital period of imaging (8-12 ?m) when the source is nearing quiescence. The fading jet component, and possibly the companion star, may contribute to the NIR flux. We derive deep mid-IR flux upper limits and NIR linear polarization upper limits. With the inclusion of radio data, we measure an almost flat jet spectral index between radio and optical; Fν∝ν˜+0.05. The data favour the jet break to optically thin emission to reside in the IR, but may shift to frequencies as high as the optical or UV during the peak of the flare. Based on observations collected at the European Southern Observatory, Chile, under ESO Programme ID 086.D-0610, the William Herschel Telescope operated on the island of La Palma by the Isaac Newton Group in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias and the Faulkes Telescopes at Haleakala, Maui, USA and Siding Spring, Australia.

  8. Correlated X-ray Spectral and Timing Behavior of the Black Hole Candidate XTE J1550-564

    CERN Document Server

    Homan, J; Van der Klis, M; Belloni, T; Van Paradijs, J; Klein-Wolt, M; Fender, R P; Méndez, M; Homan, Jeroen; Wijnands, Rudy; Klis, Michiel van der; Belloni, Tomaso; Paradijs, Jan van; Klein-Wolt, Marc; Fender, Robert P; Mendez, Mariano

    2000-01-01

    We present an analysis of data of the black hole X-ray transient XTE J1550-564, taken with RXTE between 1998 Nov 22 and 1999 May 20. The source went through several different states, which were divided into soft and hard states, based on the relative strength of the high energy power law tail. The states showed up as distinct branches in the color-color diagram, connecting to form a structure with a comb-like topology, the branch corresponding to the soft state forming the spine and the branches corresponding to the various hard states forming the teeth of the comb. The power spectral properties of each branch were correlated with their spectral properties. Three types of QPOs were found: 1-18 Hz and 100-285 Hz QPOs on the hard branches, and 15-18 Hz QPOs on and near the soft branch. The frequency of the high and low frequency QPOs on the hard branches were correlated with each other, and with spectral hardness. The behavior of the XTE J1550-564 strongly favors a two-dimensional description of black hole beha...

  9. Discovery and Monitoring of a New Black Hole Candidate XTE J1752-223 with RXTE: RMS Spectrum Evolution, BH Mass and the Source Distance

    Science.gov (United States)

    Shaposhinikov, Nikolai; Markwardt, Craig; Swank, Jean; Krimm, Hans

    2010-01-01

    We report on the discovery and monitoring observations of a new galactic black hole candidate XTE J1752-223 by Rossi X-ray Timing Explorer (RXTE). The new source appeared on the X-ray sky on October 21 2009 and was active for almost 8 months. Phenomenologically, the source exhibited the low-hard/highsoft spectral state bi-modality and the variability evolution during the state transition that matches standard behavior expected from a stellar mass black hole binary. We model the energy spectrum throughout the outburst using a generic Comptonization model assuming that part of the input soft radiation in the form of a black body spectrum gets reprocessed in the Comptonizing medium. We follow the evolution of fractional root-mean-square (RMS) variability in the RXTE/PCA energy band with the source spectral state and conclude that broad band variability is strongly correlated with the source hardness (or Comptonized fraction). We follow changes in the energy distribution of rms variability during the low-hard state and the state transition and find further evidence that variable emission is strongly concentrated in the power-law spectral component. We discuss the implication of our results to the Comptonization regimes during different spectral states. Correlations of spectral and variability properties provide measurements of the BH mass and distance to the source. The spectral-timing correlation scaling technique applied to the RXTE observations during the hardto- soft state transition indicates a mass of the BH in XTE J1752-223 between 8 and 11 solar masses and a distance to the source about 3.5 kiloparsec.

  10. X-ray timing and spectral observations of galactic black hole candidate XTE J1550-564 during outburst

    Science.gov (United States)

    Reilly, Kaice Theodore

    2003-09-01

    The timing and spectral properties of the soft X-ray transient (SXT) and microquasar XTE J1550-564 during outburst are studied, emphasizing observations made by the Unconventional Stellar Aspect (USA) Experiment. USA data show a low-frequency quasi-periodic oscillation (LFQPO) with a centroid frequency that tends to increase with increasing flux and a fractional rms amplitude which is correlated with the USA hardness ratio. Several high- frequency quasi-periodic oscillations (HFQPOs) were detected by RXTE, during periods where the LFQPO is seen to be weakening or not detectable at all. The evolution of the USA hardness ratio with time and source flux is examined. The hardness-intensity diagram shows counterclockwise cyclical evolution and possibly indicates the presence of two independent accretion flows: a geometrically thin, optically thick accretion disk and a hot sub-Keplerian flow. A model for production of the LFQPO in XTE J1550-564 is proposed, assuming that the LFQPO is a result of acoustic oscillations in a hot sub-Keplerian transition layer (TL). Under this acoustic oscillation model (AOM), the TL is an acoustic cavity having an outer boundary at RTL, where R TL ≈ Rinner, with Rinner being the radius of the accretion disk inner edge. TL resonance is interpreted as a mechanism for the LFQPO and the eigenfrequencies are associated with the LFQPO frequencies, ν LFQPO. This LFQPO mechanism requires the presence of a TL, capable of inverse-Compton scattering, with RTL regulated by a cool Keplerian accretion disk. Support for the AOM is provided by the correlation of the LFQPO percent rms amplitude with the USA hardness ratio, and other correlations and anti-correlations found in the USA, RXTE and BATSE observations. LFQPO data show increasing rms amplitude with increasing high energy flux and increasing νLFQPO with increasing low energy flux. These observations indicate that ν LFQPO is set by the accretion disk inner edge. The spectrally inferred Rinner

  11. X-Ray Flares and Oscillations from the Black Hole Candidate X-Ray Transient XTE J1650-500 at Low Luminosity

    CERN Document Server

    Tomsick, J A; Corbel, S; Kaaret, P E; Tomsick, John A.; Kalemci, Emrah; Corbel, Stephane; Kaaret, Philip

    2003-01-01

    We report on X-ray observations made with the Rossi X-ray Timing Explorer of the black hole candidate (BHC) transient XTE J1650-500 at the end of its first, and currently only, outburst. By monitoring the source at low luminosities over several months, we found 6 bright ~100 second X-ray flares and long time scale oscillations of the X-ray flux. The oscillations are aperiodic with a characteristic time scale of 14.2 days and an order of magnitude variation in the 2.8-20 keV flux. The oscillations may be related to optical "mini-outbursts" that have been observed at the ends of outbursts for other short orbital period BHC transients. The X-ray flares have durations between 62 and 215 seconds and peak fluxes that are 5-24 times higher than the persistent flux. The flares have non-thermal energy spectra and occur when the persistent luminosity is near 3E34 (d/4 kpc)^2 erg/s (2.8-20 keV). The rise time for the brightest flare demonstrates that physical models for BHC systems must be able to account for the situat...

  12. A Spectral Study of the Black Hole Candidate XTE J1752-223 in the High/Soft State with MAXI, Suzaku and Swift

    CERN Document Server

    Nakahira, Satoshi; Uedu, Yoshihiro; Yamaoka, Kazutaka; Sugizaki, Mutsumi; Mihara, Tatehiro; Matsuoka, Masaru; Yoshida, Atsumasa; Makishima, Kazuo; Ebisawa, Ken; Kubota, Aya; Yamada, Shin'ya; Negoro, Hitoshi; Hiroi, Kazuo; Ishikawa, Masaki; Kawai, Nobuyuki; Kimura, Masashi; Kitayama, Hiroki; Kohama, Mitsuhiro; Matsumura, Takanori; Morii, Mikio; Nakajima, Motoki; Serino, Motoko; Shidatsu, Megumi; Sootome, Tetsuya; Sugimori, Kousuke; Suwa, Fumitoshi; Tomida, Hiroshi; Tsuboi, Yoko; Tsunemi, Hiroshi; Ueno, Shiro; Usui, Ryuichi; Yamamoto, Takayuki; Yamazaki, Kyohei; Tashiro, Makoto S; Terada, Yukikatsu; Seta, Hiromi

    2011-01-01

    We report on the X-ray spectral analysis of the black hole candidate XTE\\ J1752--223 in the 2009--2010 outburst, utilizing data obtained with the MAXI/Gas Slit Camera (GSC), the Swift/XRT, and Suzaku, which work complementarily. As already reported by Nakahira et al. (2010) MAXI monitored the source continuously throughout the entire outburst for about eight months. All the MAXI/GSC energy spectra in the high/soft state lasting for 2 months are well represented by a multi-color disk plus power-law model. The innermost disk temperature changed from $\\sim$0.7 keV to $\\sim$0.4 keV and the disk flux decreased by an order of magnitude. Nevertheless, the innermost radius is constant at $\\sim$41 $D_{3.5}(\\cos{\\it i})^{-1/2}$ km, where $D_{3.5}$ is the source distance in units of 3.5 kpc and $i$ the inclination. The multi-color disk parameters obtained with the MAXI/GSC are consistent with those with the Swift/XRT and Suzaku. The Suzaku data also suggests a possibility that the disk emission is slightly Comptonized, ...

  13. Evidence for Spin and Energy Extraction in a Galactic Black Hole Candidate The XMM-Newton\\/EPIC-pn Spectrum of XTE J1650-500

    CERN Document Server

    Miller, J M; Wijnands, R; Reynolds, C S; Ehle, M; Freyberg, M J; Van der Klis, M; Lewin, W H G; Sánchez-Fernández, C; Castro-Tirado, A J

    2002-01-01

    We observed the Galactic black hole candidate XTE J1650-500 early in its Fall, 2001 outburst with the XMM-Newton European Photon Imaging pn Camera (EPIC-pn). The observed spectrum is consistent with the source having been in the "very high" state. We find a broad, skewed Fe K-alpha emission line which suggests that the primary in this system may be a Kerr black hole, and which indicates a steep emissivity profile that is hard to explain in terms of a standard accretion disk model. These results are quantitatively and qualitatively similar to those from an XMM-Newton observation of the Seyfert galaxy MCG--6-30-15. The steep emissivity in MCG--6-30-15 may be explained by the extraction and dissipation of rotational energy from a black hole with nearly- maximal angular momentum or material in the plunging region via magnetic connections to the inner accretion disk. If this process is at work in both sources, an exotic but fundamental general relativistic prediction may be confirmed across a factor of 10^6 in bla...

  14. Discovery and Monitoring of a new Black Hole Candidate XTE J1752-223 with RXTE: RMS spectrum evolution, BH mass and the source distance

    CERN Document Server

    Shaposhnikov, Nikolai; Swank, Jean; Krimm, Hans

    2010-01-01

    We report on the discovery and monitoring observations of a new galactic black hole candidate XTE J1752-223 by Rossi X-ray Timing Explorer (RXTE). The new source appeared on the X-ray sky on October 21 2009 and was active for almost 8 months. Phenomenologically, the source exhibited the low-hard/high-soft spectral state bi-modality and the variability evolution during the state transition that matches standard behavior expected from a stellar mass black hole binary. We model the energy spectrum throughout the outburst using a generic Comptonization model assuming that part of the input soft radiation in the form of a black body spectrum gets reprocessed in the Comptonizing medium. We follow the evolution of fractional root-mean-square (RMS) variability in the RXTE/PCA energy band with the source spectral state and conclude that broad band variability is strongly correlated with the source hardness (or Comptonized fraction). We follow changes in the energy distribution of rms variability during the low-hard st...

  15. Fermi arc electronic structure and Chern numbers in the type-II Weyl semimetal candidate MoxW1 -xTe2

    Science.gov (United States)

    Belopolski, Ilya; Xu, Su-Yang; Ishida, Yukiaki; Pan, Xingchen; Yu, Peng; Sanchez, Daniel S.; Zheng, Hao; Neupane, Madhab; Alidoust, Nasser; Chang, Guoqing; Chang, Tay-Rong; Wu, Yun; Bian, Guang; Huang, Shin-Ming; Lee, Chi-Cheng; Mou, Daixiang; Huang, Lunan; Song, You; Wang, Baigeng; Wang, Guanghou; Yeh, Yao-Wen; Yao, Nan; Rault, Julien E.; Le Fèvre, Patrick; Bertran, François; Jeng, Horng-Tay; Kondo, Takeshi; Kaminski, Adam; Lin, Hsin; Liu, Zheng; Song, Fengqi; Shin, Shik; Hasan, M. Zahid

    2016-08-01

    It has recently been proposed that electronic band structures in crystals can give rise to a previously overlooked type of Weyl fermion, which violates Lorentz invariance and, consequently, is forbidden in particle physics. It was further predicted that MoxW1 -xTe2 may realize such a type-II Weyl fermion. Here, we first show theoretically that it is crucial to access the band structure above the Fermi level ɛF to show a Weyl semimetal in MoxW1 -xTe2 . Then, we study MoxW1 -xTe2 by pump-probe ARPES and we directly access the band structure >0.2 eV above ɛF in experiment. By comparing our results with ab initio calculations, we conclude that we directly observe the surface state containing the topological Fermi arc. We propose that a future study of MoxW1 -xTe2 by pump-probe ARPES may directly pinpoint the Fermi arc. Our work sets the stage for the experimental discovery of the first type-II Weyl semimetal in MoxW1 -xTe2 .

  16. Reanalysis of the RXTE observations of the black-hole candidate XTE J1650-500 in the 2001/2002 outburst

    Institute of Scientific and Technical Information of China (English)

    Li-Hong Yan; Jian-Cheng Wang

    2012-01-01

    We present the results of the spectral fits made to 59 Rossi X-ray Timing Explorer (RXTE) observations of the Galactic X-Ray Black-Hole Candidate XTE J1650-500 covering the first 30d of its 2001/2002 outburst when the source was in a transition from the hard state to the soft state.The photon spectra can be well fitted with a phenomenological model of a power-law/cutoff power-law and a physical model of bulk-motion Comptonization.The spectral properties smoothly evolve away from the hard state and then stay in the soft state.The fitting results of the physical model reveal the peak of the burst had a flux of 2.90 × 10-8 erg cm-2 s-1 in the 2-100 keV energy range and was observed on 2001 Sep.9; it transitioned to the hard state.The total flux decays by a factor of ~3 as it evolves into the soft state.The photon index Γ increases from ~ 1.5 in the hard state and stays at ~2.5 in the soft state.We found that the effective area of the high-energy X-ray emission region (the Compton cloud) decreases,i.e.the area of the Compton cloud decreases by a factor of ~23 during the transition from the hard state to the soft state.Combining the new radio and quasi-periodic oscillation studies,the model of total flux in the 2-100 keV energy range,the jet emission and the timing analysis during the state transition,we suggest a possible geometry and evolution for the (jet+corona+disk) system,like that proposed by Kalemci et al.based on enhanced lags and peak frequency shift during the transition.

  17. Unoccupied electronic structure and signatures of topological Fermi arcs in the Weyl semimetal candidate Mo$_x$W$_{1-x}$Te$_2$

    OpenAIRE

    Belopolski, Ilya; Xu, Su-Yang; Ishida, Yukiaki; Pan, Xingchen; Yu, Peng; Sanchez, Daniel S.; Neupane, Madhab; Alidoust, Nasser; Chang, Guoqing; Chang, Tay-Rong; WU, YUN; Bian, Guang; Zheng, Hao; Huang, Shin-Ming; Lee, Chi-Cheng

    2015-01-01

    Weyl semimetals have sparked intense research interest, but experimental work has been limited to the TaAs family of compounds. Recently, a number of theoretical works have predicted that compounds in the Mo$_x$W$_{1-x}$Te$_2$ series are Weyl semimetals. Such proposals are particularly exciting because Mo$_x$W$_{1-x}$Te$_2$ has a quasi two-dimensional crystal structure well-suited to many transport experiments, while WTe$_2$ and MoTe$_2$ have already been the subject of numerous proposals for...

  18. Optical behaviour of XTE J1550-564 and XTE J1859+226 from outburst to quiescence

    DEFF Research Database (Denmark)

    Sanchez-Fernandez, C.; Castro-Tirado, A.J.; Gimenez, A.;

    2001-01-01

    We present here the optical light curves of the Soft X-ray Transients XTE J1550-564 and XTEJ1859+226 from outburst to quiescence.......We present here the optical light curves of the Soft X-ray Transients XTE J1550-564 and XTEJ1859+226 from outburst to quiescence....

  19. Disentangling the NIR/optical emission of the black hole XTE J1650-500 during outburst

    CERN Document Server

    Curran, P A; Heras, J A Zurita

    2012-01-01

    While the sources of X-ray and radio emission in the different states of low-mass X-ray binaries are relatively well understood, the origin of the near-infrared (NIR) and optical emission is more often debated. It is likely that the NIR/optical flux originates from an amalgam of different emission regions, because it occurs at the intersecting wavelengths of multiple processes. We aim to identify the NIR/optical emission region(s) of one such low-mass X-ray binary and black hole candidate, XTE J1650-500, via photometric, timing, and spectral analyses. We present unique NIR/optical images and spectra, obtained with the ESO-New Technology Telescope, during the peak of the 2001 outburst of XTE J1650-500. The data suggest that the NIR/optical flux is due to a combination of emission mechanisms including a significant contribution from X-ray reprocessing and, at early times in the hard state, a relativistic jet that is NIR/radio dim compared to similar sources.The jet of XTE J1650-500 is relatively weak compared t...

  20. Multiwavelength observations revealing the outbursts of the two soft X-ray transients XTE J1859+226 and XTE J1118+480

    CERN Document Server

    Chaty, S; Hynes, R I; Shrader, C R; Cui, W; Mauche, C W; Norton, A J; Solheim, J E; Ostensen, R; Geballe, T R; Ioannou, Z; King, A R

    2001-01-01

    We report here on multiwavelength observations of the two new soft X-ray transients (SXTs) XTE J1859+226 and XTE J1118+480, which we observed with HST/RXTE/UKIRT. For XTE J1118+480 we also used EUVE since it is located at a very high galactic latitude and suffers from very low extinction. The two sources exhibited very different behaviour. XTE J1859+226 seems quite normal and therefore a good object for testing the accretion mechanisms in place during the outbursts, XTE J1118+480 is much more unusual because it exhibits i) a low X-ray to optical ratio and ii) a strong non-thermal contribution in the radio to optical domain, which is likely to be due to synchrotron emission. We concentrate here on the near-infrared (NIR) and optical observations of these two systems.

  1. Multiwavelength observations revealing the outbursts of the soft X-ray transients XTE J1859+226 and XTE J1118+480

    CERN Document Server

    Chaty, S; Hynes, R I; Shrader, C R; Cui, W

    2000-01-01

    We report multiwavelength observations of the two soft X-ray transients (SXTs) XTE J1859+226 and XTE J1118+480, which we observed with HST, RXTE and UKIRT. The two sources exhibited very different behaviour. XTE J1859+226 showed a thermal-viscous disc instability outburst modified by irradiation. XTE J1118+480, which we also observed with EUVE since it is located at a very high galactic latitude and suffers from very low extinction, is much more unusual. It exhibits i) a low X-ray to optical flux ratio and ii) a strong non-thermal contribution throughout the spectrum, which is likely to be due to synchrotron emission. We concentrate here on their evolution in the course of their outbursts.

  2. VLT spectroscopy of XTE J2123-058 during quiescence

    OpenAIRE

    Casares, J.; Dubus, G.; Shahbaz, T; Zurita, C.; Charles, P. A.

    2001-01-01

    We present VLT low resolution spectroscopy of the neutron star X-ray transient XTE J2123-058 during its quiescent state. Our data reveal the presence of a K7V companion which contributes 77 % to the total flux at 6300 A and orbits the neutron star at K_2 = 287 +/- 12 km/s. Contrary to other soft X-ray transients (SXTs), the Halpha emission is almost exactly in antiphase with the velocity curve of the optical companion. Using the light-center technique we obtain K_1 = 140 +/- 27 km/s and hence...

  3. On the Lack of Thermal Emission from the Quiescent Black Hole XTE J1118+480: Evidence for the Event Horizon

    OpenAIRE

    McClintock, Jeffrey E.; Narayan, Ramesh; Rybicki, George B.

    2004-01-01

    A soft component of thermal emission is very commonly observed from the surfaces of quiescent, accreting neutron stars. We searched with Chandra for such a surface component of emission from the dynamical black-hole candidate XTE J1118+480 (= J1118), which has a primary mass of about 8 solar masses. None was found, as one would expect if the compact X-ray source is a bona fide black hole that possesses an event horizon. The X-ray spectrum of J1118 is well-fitted by a simple power-law model. I...

  4. Delta XTE Spacecraft Solar Panel Deployment, Hangar AO at Cape Canaveral Air Station

    Science.gov (United States)

    1995-01-01

    The footage shows technicians in the clean room checking and adjusting the deployment mechanism of the solar panel for XTE spacecraft. Other scenes show several technicians making adjustments to software for deployment of the solar panels.

  5. Discovery of a Transient Magnetar: XTE J1810-197

    Science.gov (United States)

    Ibrahim, Alaa I.; Markwardt, Craig B.; Swank, Jean H.; Ransom, Scott; Roberts, Mallory; Kaspi, Victoria; Woods, Peter M.; Safi-Harb, Samar; Balman, Solen; Parke, William C.

    2004-01-01

    We report the discovery of a new X-ray pulsar, XTE J1810-197, that was serendipitously discovered on 2003 July 15 by the Rossi X-Ray Timing Explorer (RXTE) while observing the soft gamma repeater SGR 1806-20. The pulsar has a 5.54 s spin period, a soft X-ray spectrum (with a photon index of approx. = 4). and is detectable in earlier RXTE observations back to 2003 January but not before. These show that a transient outburst began between 2002 November 17 and 2003 January 23 and that the source's persistent X-ray flux has been declining since then. The pulsar exhibits a high spin-down rate P approx.= l0(exp -11) s/s with no evidence of Doppler shifts due to a binary companion. The rapid spin-down rate and slow spin period imply a supercritical characteristic magnetic field B approx. = 3 x l0(exp 14) G and a young age tau less than or = 7600 yr. Follow-up Chandra observations provided an accurate position of the source. Within its error radius, the 1.5 m Russian-Turkish Optical Telescope found a limiting magnitude R(sub c) = 21.5. All such properties are strikingly similar to those of anomalous X-ray pulsars ad soft gamma repeaters, providing strong evidence that the source is a new magnetar. However, archival ASCA and ROSAT observations found the source nearly 2 orders of magnitude fainter. This transient behavior and the observed long-term flux variability of the source in absence of an observed SGR-like burst activity make it the first confirmed transient magnetar and suggest that other neutron stars that share the properties of XTE 51810- 197 during its inactive phase may be unidentified transient magnetars awaiting detection via a similar activity. This implies a larger population of magnetars than previously surmised and a possible evolutionary connection between magnetars and other neutron star families. Subject headings: pulsars: general -pulsars: individual (XTE 51810- 197) - stars: magnetic fields -

  6. Near-infrared Observations of Magnetars: XTE J1810-197, 1RXS J1708-4009, 1E 1841-045 and SGR 1900+14

    CERN Document Server

    Testa, V; Mignani, R P; Israel, G L; Perna, R; Chaty, S; Stella, L; Covino, S; Turolla, R; Zane, S; Curto, G Lo; Campana, S; Marconi, G; Mereghetti, S

    2007-01-01

    . We report on near-infrared (IR) observations of the three anomalous X-ray pulsars XTE J1810-197, 1RXS J1708-4009, 1E 1841-045 and the soft gamma-ray repeater SGR 1900+14, taken with the ESO-VLT, the Gemini, and the CFHT telescopes. . This work is aimed at identifying and/or confirming the IR counterparts of these magnetars, as well as at measuring their possible IR variability. . In order to perform photometry of objects as faint as Ks~20, we have used data taken with the largest telescopes, equipped with the most advanced IR detectors and in most of the cases with Adaptive Optics devices. The latter are critical to achieve the sharp spatial accuracy required to pinpoint faint objects in crowded fields. . We confirm with high confidence the identification of the IR counterpart to XTE J1810-197, and its IR variability. For 1E 1841-045 and SGR 1900+14 we propose two candidate IR counterparts based on the detection of IR variability. For 1RXS J1708-4009 we show that none of the potential counterparts within th...

  7. VLT spectroscopy of XTE J2123-058 during quiescence

    CERN Document Server

    Casares, J; Shahbaz, T; Zurita, C; Charles, P A

    2001-01-01

    We present VLT low resolution spectroscopy of the neutron star X-ray transient XTE J2123-058 during its quiescent state. Our data reveal the presence of a K7V companion which contributes 77 % to the total flux at 6300 A and orbits the neutron star at K_2 = 287 +/- 12 km/s. Contrary to other soft X-ray transients (SXTs), the Halpha emission is almost exactly in antiphase with the velocity curve of the optical companion. Using the light-center technique we obtain K_1 = 140 +/- 27 km/s and hence q=K_1/K_2=M_2/M_1= 0.49 +/- 0.10. This, combined with a previous determination of the inclination angle (i=73 +/- 4) yields M_1 = 1.55 +/- 0.31 Msun and M_2 = 0.76 +/- 0.22 Msun. M_2 agrees well with the observed spectral type. Doppler tomography of the Halpha emission shows a non-symmetric accretion disc distribution mimicking that seen in SW Sex stars. Although we find a large systemic velocity of -110 +/- 8 km/s this value is consistent with the galactic rotation velocity at the position of J2123-058, and hence a halo...

  8. XTE J1701-407 INTEGRAL and Swift observations

    DEFF Research Database (Denmark)

    Soldi, S.; Beckmann, V.; Eckert, D.;

    2008-01-01

    INTEGRAL has observed the Galactic center region starting September 18, 2008 through a long key program (KP) and several ToO observations of H1743-322. In the course of these observations, the neutron star LMXB XTE J1701-407 (Markwardt et al. 2008, ATel #1569 and ATel #1616, ATel #1621) has been...... detected by IBIS/ISGRI in the 20-80 keV band. The source was always outside the field of view of the X-ray monitor JEM-X. In the latest observation, the source was also detected in the 40-80 keV band with 14 ± 2 mCrab. Simultaneous to this observation a Swift ToO was performed, starting at 2008-10-18T14......:27 with an on-source time of 1.7 ksec. The combined spectrum of Swift/XRT and IBIS/ISGRI (33 ksec) can be represented by an absorbed power law with intrinsic NH = 2.2e22 1/cm^2 and photon index 2.1 ± 0.1. The model flux in the 2-50 keV band is 3e-10 erg/cm^2/sec. Assuming a maximum distance of 6 kpc...

  9. XTE J1550-564 A superluminal ejection during the September 1998 outburst

    CERN Document Server

    Hannikainen, D C; Hunstead, R W; McIntyre, V; Lovell, J; Reynolds, J; Tzioumis, T; Wu, K

    2000-01-01

    In 1998 September, the X-ray transient XTE J1550-564 underwent a major outburst in soft and hard X-rays, followed by a radio flare. Australian Long Baseline Array images obtained shortly after the peak in the radio flare showed evolving structure. The components observed have an apparent separation velocity of >2c.

  10. Evolution of the X-ray Properties of the Transient Magnetar XTE J1810-197

    CERN Document Server

    Alford, Jason

    2016-01-01

    We report on X-ray observations of the 5.54 s transient magnetar XTE J1810-197 using the XMM-Newton and Chandra observatories, analyzing new data from 2008 through 2014, and re-analyzing data from 2003 through 2007 with the benefit of these six years of new data. From the discovery of XTE J1810-197 during its 2003 outburst to the most recent 2014 observations, its 0.3-10 keV X-ray flux has declined by a factor of about 50 from 4.1E-11 to 8.1E-13 erg/cm^2/s. Its X-ray spectrum has now reached a steady state. Pulsations continue to be detected from a 0.3 keV thermal hot-spot that remains on the neutron star surface. The luminosity of this hot-spot exceeds XTE J1810-197's spin down luminosity, indicating continuing magnetar activity. We find that XTE J1810-197's X-ray spectrum is best described by a multiple component blackbody model in which the coldest 0.14 keV component likely originates from the entire neutron star surface, and the thermal hot-spot is, at different epochs, well described by an either one or ...

  11. Study of the Mg incorporation in CdTe for developing wide band gap Cd{sub 1-x}Mg{sub x}Te thin films for possible use as top-cell absorber in a tandem solar cell

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, Omar S. [Centro de Investigacion en Energia, Universidad Nacional Autonoma de Mexico, 62580 Temixco, Morelos (Mexico); Universidad Politecnica del Estado de Guerrero, Comunidad de Puente Campuzano, C.P. 40325 Taxco de Alarcon, Guerrero (Mexico); Millan, Aduljay Remolina [Centro de Investigacion en Energia, Universidad Nacional Autonoma de Mexico, 62580 Temixco, Morelos (Mexico); Huerta, L.; Santana, G. [Instituto de Investigaciones en Materiales, Universidad Nacional Autonoma de Mexico. C.P 04510 Mexico D.F. (Mexico); Mathews, N.R.; Ramon-Garcia, M.L.; Morales, Erik R. [Centro de Investigacion en Energia, Universidad Nacional Autonoma de Mexico, 62580 Temixco, Morelos (Mexico); Mathew, X., E-mail: xm@cie.unam.mx [Centro de Investigacion en Energia, Universidad Nacional Autonoma de Mexico, 62580 Temixco, Morelos (Mexico)

    2012-02-15

    Highlights: Black-Right-Pointing-Pointer Thin films of Cd{sub 1-x}Mg{sub x}Te with high spatial uniformity and band gap in the range of 1.6-1.96 eV were deposited by vacuum co-evaporation of CdTe and Mg. Black-Right-Pointing-Pointer Obtained Cd{sub 1-x}Mg{sub x}Te films have the structural characteristics of the CdTe, evidence of the change in atomic scattering due to incorporation of Mg was observed. Black-Right-Pointing-Pointer XRD and XPS data confirmed the incorporation of Mg in the lattice of CdTe. Black-Right-Pointing-Pointer SEM images revealed the impact of Mg incorporation on the morphology of the films, the changes in grain size and grain morphology are noticeable. - Abstract: Thin films of Cd{sub 1-x}Mg{sub x}Te with band gap in the range of 1.6-1.96 eV were deposited by vacuum co-evaporation of CdTe and Mg on glass substrates heated at 300 Degree-Sign C. Different experimental techniques such as XRD, UV-vis spectroscopy, SEM, and XPS were used to study the effect of Mg incorporation into the lattice of CdTe. The band gap of the films showed a clear tendency to increase as the Mg content in the film is increased. The Cd{sub 1-x}Mg{sub x}Te films maintain all the structural characteristics of the CdTe, however, diminishing of intensity for the XRD patterns is observed due to both change in preferential orientation and change in atomic scattering due to the incorporation of Mg. SEM images showed significant evidences of morphological changes due to the presence of Mg. XRD, UV-vis spectroscopy, and XPS data confirmed the incorporation of Mg in the lattice of CdTe. The significant increase in band gap of CdTe due to incorporation of Mg suggests that the Cd{sub 1-x}Mg{sub x}Te thin film is a candidate material to use as absorber layer in the top-cell of a tandem solar cell.

  12. Evolution of the X-ray Properties of the Transient Magnetar XTE J1810-197

    Science.gov (United States)

    Alford, Jason

    2016-04-01

    We report on X-ray observations of the 5.54 s transient magnetar XTE J1810-197 using the XMM-Newton and Chandra observatories, analyzing new data from 2008 through 2014, and re-analyzing data from 2003 through 2007 with the benefit of these six years of new data. From the discovery of XTE J1810-197 during its 2003 outburst to the most recent 2014 observations, its 0.3-10 keV X-ray flux has declined by a factor of about 50 from 4.1E-11 to 8.1E-13 erg/cm^2/s. Its X-ray spectrum has now reached a steady state. Pulsations continue to be detected from a 0.3 keV thermal hot-spot that remains on the neutron star surface. The luminosity of this hot-spot exceeds XTE J1810-197's spin down luminosity, indicating continuing magnetar activity. We find that XTE J1810-197's X-ray spectrum is best described by a multiple component blackbody model in which the coldest 0.14 keV component likely originates from the entire neutron star surface, and the thermal hot-spot is, at different epochs, well described by an either one or two-component blackbody model. A 1.2 keV absorption line, possibly due to resonant proton scattering, is detected at all epochs. The X-ray flux of the hot spot decreased by approximately 20% between 2008 March and 2009 March, the same period during which XTE J1810-197 became radio quiet.

  13. NIR and optical observations of the failed outbursts of black hole binary XTE J1550-564

    CERN Document Server

    Curran, P A

    2013-01-01

    A number of low mass X-ray binaries (LMXBs) undergo "failed outbursts" in which, instead of evolving through the canonical states, they remain in a hard state throughout the outburst. While the sources of X-ray and radio emission in the hard state are relatively well understood, the origin of the near infrared (NIR) and optical emission is more complex though it likely stems from an amalgam of different emission processes, occurring as it does, at the intersecting wavelengths of those processes. We aim to identify the NIR/optical emission region(s) during a number of failed outbursts of one such low mass X-ray binary and black hole candidate, XTE J1550-564, in order to confirm or refute their classification as hard-state, failed outbursts. We present unique NIR/optical images and spectra, obtained with the ESO-New Technology Telescope, during the failed outbursts of 2001 and 2000. We compare the NIR/optical photometric, timing, and spectral properties with those expected for the different emission mechanisms ...

  14. XTE J1752-223 in outburst: a persistent radio jet, dramatic flaring, multiple ejections and linear polarisation

    CERN Document Server

    Brocksopp, Catherine; Tzioumis, Tasso; Broderick, Jess; Rodriguez, Jerome; Yang, Jun; Fender, Rob; Paragi, Zsolt

    2013-01-01

    The black hole candidate, XTE J1752-223, was discovered in 2009 October when it entered an outburst. We obtained radio data from the Australia Telescope Compact Array for the duration of the ~9 month event. The lightcurves show that the radio emission from the compact jet persisted for the duration of an extended hard state and through the transition to the intermediate state. The flux then rose rapidly by a factor of 10 and the radio source entered a series of at least 7 maxima, the first of which was likely to be emission associated with the compact jet. The subsequent 6 flares were accompanied by variable behaviour in terms of radio spectrum, degree of linear polarisation, morphology and associated X-ray behaviour. They were, however, remarkably similar in terms of the estimated minimum power required to launch such an ejection event. We compare the timing of radio peaks with the location of the ejecta, imaged by contemporaneous VLBI experiments. We then discuss the mechanism behind the events, in terms of...

  15. X-ray softening during the 2008 outburst of XTE J1810-189

    CERN Document Server

    Weng, Shan-Shan; Yi, Shu-Xu; Rong, Yu; Gao, Xu-Dong

    2015-01-01

    XTE J1810-189 underwent an outburst in 2008, and was observed over $\\sim 100$ d by RXTE. Performing a time-resolved spectral analysis on the photospheric radius expansion burst detected on 2008 May 4, we obtain the source distance in the range of 3.5--8.7 kpc for the first time. During its outburst, XTE J1810-189 did not enter into the high/soft state, and both the soft and hard colours decreased with decreasing flux. The fractional rms remained at high values ($\\sim 30$ per cent). The RXTE/PCA spectra for 3-25 keV can be described by an absorbed power-law component with an additional Gaussian component, and the derived photon index $\\Gamma$ increased from $1.84\\pm0.01$ to $2.25\\pm0.04$ when the unabsorbed X-ray luminosity in 3-25 keV dropped from $4\\times10^{36}$ ergs s$^{-1}$ to $6\\times10^{35}$ ergs s$^{-1}$. The relatively high flux, dense observations and broadband spectra allow us to provide strong evidence that the softening behaviour detected in the outburst of XTE J1810-189 originates from the evolut...

  16. Looking into the Theory of Pulsar Accretion: Cen X-3 and XTE J1946+274

    CERN Document Server

    Marcu, Diana M; Gottlieb, Amy M; Wolff, Michael T; Becker, Peter A; Wilms, Joern; Ferrigno, Carlo; Wood, Kent S

    2015-01-01

    This is an overview of pulsar accretion modeling. The physics of pulsar accretion, i.e., the process of plasma flow onto the neutron star surface, can be constrained from the spectral properties of the X-ray source. We discuss a new implementation of the physical continuum model developed by Becker and Wolff (2007, ApJ 654, 435). The model incorporates Comptonized blackbody, bremsstrahlung, and cyclotron emission. We discuss preliminary results of applying the new tool to the test cases of Suzaku data of Cen X-3 and XTE J1946+274. Cen X-3 is a persistent accreting pulsar with an O-star companion observed during a bright period. XTE J1946+274 is a transient accreting pulsar with a Be companion observed during a dim period. Both sources show spectra that are well described with an empirical Fermi Dirac cutoff power law model. We extend the spectral analysis by making the first steps towards a physical description of Cen X-3 and XTE J1946+274.

  17. The Fading of Transient Anomalous X-Ray Pulsar XTE J1810-197

    Science.gov (United States)

    Halpern, J. P.; Gotthelf, E. V.

    2005-01-01

    Three observations of the 5.54 s transient anomalous X-ray pulsar XTE J1810-197 obtained over 6 months with the Newton X-ray Multi-Mirror (XMM-Newton) mission are used to study its spectrum and pulsed light curve as the source fades from outburst. The decay is consistent with an exponential of time constant ~300 days but not a power law as predicted in some models of sudden deep crustal heating events. All spectra are well fitted by a blackbody plus a steep power law, a problematic model that is commonly fitted to anomalous X-ray pulsars (AXPs). A two-temperature blackbody fit is also acceptable and better motivated physically in view of the faint optical/IR fluxes, the X-ray pulse shapes that weakly depend on energy in XTE J1810-197, and the inferred emitting areas that are less than or equal to the surface area of a neutron star. The fitted temperatures remained the same while the flux declined by 46%, which can be interpreted as a decrease in area of the emitting regions. The pulsar continues to spin down, albeit at a reduced rate of (5.1+/-1.6)×10-12 s s-1. The inferred characteristic age τc≡P/2P~17,000 yr, magnetic field strength Bs~1.7×1014 G, and outburst properties are consistent with both the outburst and quiescent X-ray luminosities being powered by magnetic field decay, i.e., XTE J1810-197 is a magnetar.

  18. An unusual timing and spectral state of a black hole microquasar XTE J1550-564

    Institute of Scientific and Technical Information of China (English)

    Ying-Kang Jin; Shuang-Nan Zhang; Ti-Pei Li

    2009-01-01

    An unusual timing and spectral state of a black hole microquasar XTE J1550-564 observed with RXTE is analyzed. Millisecond variabilities are found, which are significantly shorter than the minimum possible time scale in the light curves of black hole binaries, as suggested by Sunyaev & Revnivtsev (2000). The X-ray spectral fitting result indicates that there is an unusual soft component in the spectrum, which may be responsible for the millisecond variabilities. The millisecond variabilities as well as the unusual soft spectral component should be produced from some small, but independent active regions in the accretion disk.

  19. Radio Emission from the X-ray transient XTE J1550-564

    CERN Document Server

    Hannikainen, D C; Hunstead, R W; Lovell, J; McIntyre, V; Reynolds, J; Soria, R; Tzioumis, T

    2001-01-01

    We report multifrequency radio observations of XTE J1550-564 obtained with the Molonglo Observatory Synthesis Telescope and the Australia Telescope Compact Array at the time of its discovery and subsequent hard and soft X-ray outburst in 1998 September. A large radio flare was observed, peaking about 1.8 days after the X-ray flare. In addition, we present Australian Long Baseline Array images obtained shortly after the maximum of the radio flare which show evolving structure. The apparent separation velocity of the two outermost components is v>2c.

  20. Doppler Tomography of XTE J2123-058 and Other Neutron Star LMXBs

    OpenAIRE

    Hynes, R.I.; Charles, P. A.; C. A. Haswell; Casares, J.; Zurita, C.

    2000-01-01

    We describe Doppler tomography obtained in the 1998 outburst of the neutron star low mass X-ray binary (LMXB) XTE J2123-058. This analysis, and other aspects of phase-resolved spectroscopy, indicate similarities to SW Sex systems, except that anomalous emission kinematics are seen in HeII, whilst phase 0.5 absorption is confined to H alpha. This separation of these effects may provide tighter constraints on models in the LMXB case than is possible for SW Sex systems. We will compare results f...

  1. Acoustostimulated change of electron mobility in n-CdxHg1-xTe crystals

    International Nuclear Information System (INIS)

    Electron mobility of n-CdxHg1-xTe crystals is investigated at a dynamic ultrasound loading. A mobility increases in the region of impurity conductivity (T 120 K) for all measured samples are observed. It is demonstrated that the main reason for the mobility increase in the region of impurity conductivity is down sizing of the macropotential in the crystal, and an increase of the scattering intensity on optical phonons results in a decrease of carrier's mobility in the region of intrinsic conductivity

  2. Optical re-brightening of the black hole binary XTE J1859+226

    Science.gov (United States)

    Corral-Santana, J. M.; Rodríguez-Gil, P.; Hurley, D.; Casares, J.

    2010-09-01

    Observations of the black hole binary XTE J1859+226 revealed an unexpected optical re-brightening. Images were taken with the Nordic Optical Telescope (NOT) using ALFOSC on Jul 13-14, the William Herschel Telescope (WHT) with ACAM on Aug 8 and the Isaac Newton Telescope (INT) with WFC on Aug 19 at the Observatorio del Roque de los Muchachos, La Palma, Spain. The target is found ~1 magnitude brighter than its quiescence level of R=22.48 +- 0.07 as reported in Zurita et al.

  3. The variable radio counterpart and possible large-scale jet of the new Z source XTE J1701-462

    NARCIS (Netherlands)

    R.P. Fender; M. Dahlem; J. Homan; S. Corbel; R. Sault; T. Belloni

    2007-01-01

    We report radio observations, made with the Australia Telescope Compact Array, of the X-ray transient XTE J1701-462. This system has been classified as a new `Z' source, displaying characteristic patterns of behaviour probably associated with accretion on to a low magnetic field neutron star at clos

  4. Correlations in Horizontal Branch Oscillations and Break Components in XTE J1701-462 and GX 17+2

    CERN Document Server

    Bu, Qing-cui; Li, Zhao-sheng; Qu, Jin-lu; Belloni, T M; Zhang, Liang

    2014-01-01

    We studied the horizontal branch oscillations (HBO) and the band-limited components observed in the power spectra of the transient neutron star low-mass X-ray binary XTE J1701-462 and the persistent "Sco-like" Z source GX 17+2. These two components were studied based on the state-resolved spectra. We found that the frequencies of XTE J1701-462 lie on the known correlations (WK and PBK), showing consistency with other types of X-ray binaries (black holes, atoll sources and millisecond X-ray pulsars). However, GX 17+2 is shifted from the WK correlation like other typical Z sources. We suggest that the WK/PBK main track forms a boundary which separates persistent sources from transient sources. The characteristic frequencies of break and HBO are independent of accretion rate in both sources, although it depends on spectral models. We also report the energy dependence of the HBO and break frequencies in XTE J1701-462 and how the temporal properties change with spectral state in XTE J1701-462 and GX 17+2. We studi...

  5. The Variable Quiescent X-Ray Emission of the Neutron Star Transient XTE J1701-462

    NARCIS (Netherlands)

    Fridriksson, Joel K.; Homan, J.; Wijnands, R.; Cackett, E. M.; Degenaar, N.; Mendez, M.; Altamirano, D.; Brown, E. F.; Belloni, T. M.; Lewin, W. H. G.

    2011-01-01

    We have monitored the cooling of the neutron star in the transient low-mass X-ray binary XTE J1701-462 with Chandra and XMM-Newton since the source entered quiescence in 2007 after an exceptionally luminous 19-month outburst. A recent Chandra observation made almost 1200 days into quiescence indicat

  6. The Reawakening of the Sleeping X-ray Pulsar XTE J1946+274

    Science.gov (United States)

    Mueller, Sebastian; Mueller, Sebastian; Kuechnel, Matthias; Fuerst, Felix; Kreykenbohm, Ingo; Sagredo, Macarena; Obst, Maria; Wilms, Joern; Caballero, Isabel; Potttschmidt, Katja; Ferrigno, Carlo; Rothschild, Richard E.

    2012-01-01

    We report on a series of outbursts of the high mass X-ray binary XTE 11946+274 in 2010/2011 as observed with INTEGRAL, RXTE, and Swift. We discuss possible mechanisms resulting in the extraordinary outburst behavior of this source. The X-ray spectra can be described by standard phenomenological models, enhanced by an absorption feature of unknown origin at about 10 keV and a narrow iron K alpha fluorescence line at 6.4keV, which are variable in flux and pulse phase. We find possible evidence for the presence of a cyclotron resonance scattering feature at about 25 keV at the 93% level. The presence of a strong cyclotron line at 35 keV seen in data from the source's 1998 outburst and confirmed by a reanalysis of these data can be excluded. This result indicates that the cyclotron line feature in XTE 11946+274 is variable between individual outbursts.

  7. The accretion rate independence of horizontal branch oscillation in XTE J1701-462

    CERN Document Server

    Li, Zhaosheng; Qu, Jinlu; Bu, Qingcui; Wang, Dehua; Xu, Renxin

    2014-01-01

    We study the temporal and energy spectral properties of the unique neutron star low-mass X-ray binary XTE J1701-462. After assuming the HB/NB vertex as a reference position of accretion rate, the horizontal branch oscillation (HBO) of the HB/NB vertex is roughly 50 Hz. It indicates that the HBO is independent with the accretion rate or the source intensity. The spectral analysis shows $R_{\\rm{in}}\\propto\\dot{M}_{\\rm{Disk}}^{2.9\\pm0.09}$ in the HB/NB vertex and $R_{\\rm{in}}\\propto\\dot{M}_{\\rm{Disk}}^{1.7\\pm0.06}$ in the NB/FB vertex, which implies that different accretion rate may be produced in the HB/NB vertex and the NB/FB vertex. The Comptonization component could be fitted by constrained broken power law (CBPL) or nthComp. Different with GX 17+2, the frequencies of HBO positively correlate with the inner disk radius, which contradict with the prediction of Lense-Thirring precession model. XTE J1701-462, both in the Cyg-like phase and in the Sco-like phase, follows a positive correlation between the break ...

  8. Doppler tomography of XTE J1118+480 revealing chromospheric emission from the secondary star

    Science.gov (United States)

    Zurita, C.; González Hernández, J. I.; Escorza, A.; Casares, J.

    2016-08-01

    Doppler tomography of emission lines in low-mass X-ray binaries allows us to investigate the structure and variability of the accretion discs as well as possible activity arising from the secondary stars. We present Doppler maps of the black hole binary XTE J1118+480 from spectra obtained using OSIRIS@GTC during quiescence on four different nights in 2011 and 2012. Doppler imaging of the Hα line shows, for the first time, a narrow component from the secondary star with observed equivalent widths varying in the range 1.2-2.9 Å but not correlated with the veiling of the accretion disc. The Hα flux of the secondary star is too large to be powered by X-ray irradiation, supporting chromospheric activity, possibly induced by rapid rotation, as the most likely origin of this feature in the black hole X-ray binary XTE J1118+480. In addition, we detect variations in the centroid of the Hα line on nightly basis. These are likely caused by a precessing accretion disc, although with a much lower amplitude (˜50 km s-1) than previously observed.

  9. X-ray Observation of XTE J2012+381 during the 1998 Outburst

    Indian Academy of Sciences (India)

    S. Naik; P. C. Agrawal; B. Paul; A. R. Rao; S. Seetha; Κ. Kasturirangan

    2000-06-01

    The outburst of X-ray transient source XTE J2012+381 was detected by the RXTE All-Sky Monitor on 1998 May 24th. Following the outburst, X-ray observations of the source were made in the 2-18keV energy band with the Pointed Proportional Counters of the Indian X-ray Astronomy Experiment (IXAE) on-board the Indian satellite IRS-P3 during 1998 June 2nd-10th. The X-ray flux of the source in the main outburst decreased exponentially during the period of observation. No large amplitude short-term variability in the intensity is detected from the source. The power density spectrum obtained from the timing analysis of the data shows no indication of any quasi-periodic oscillations in 0.002-0.5 Hz band. The hardness ratio i.e. the ratio of counts in 6-18 keV to 2-6 keV band, indicates that the X-ray spectrum is soft with spectral index > 2. From the similarities of the X-ray properties with those of other black hole transients, we conclude that the X-ray transient XTE J2012+381 is likely to be a black hole.

  10. The reawakening of the sleeping X-ray pulsar XTE J1946+274

    CERN Document Server

    Müller, Sebastian; Caballero, Isabel; Pottschmidt, Katja; Fürst, Felix; Kreykenbohm, Ingo; Sagredo, Macarena; Obst, Maria; Wilms, Jörn; Ferrigno, Carlo; Rothschild, Richard E; Staubert, Rüdiger

    2012-01-01

    We report on a series of outbursts of the high mass X-ray binary XTE J1946+274 in 2010/2011 as observed with INTEGRAL, RXTE, and Swift. We discuss possible mechanisms resulting in the extraordinary outburst behavior of this source. The X-ray spectra can be described by standard phenomenological models, enhanced by an absorption feature of unknown origin at about 10 keV and a narrow iron K alpha fluorescence line at 6.4 keV, which are variable in flux and pulse phase. We find possible evidence for the presence of a cyclotron resonance scattering feature at about 25 keV at the 93% level. The presence of a strong cyclotron line at 35 keV seen in data from the source's 1998 outburst and confirmed by a reanalysis of these data can be excluded. This result indicates that the cyclotron line feature in XTE J1946+274 is variable between individual outbursts.

  11. The variable spin-down rate of the transient magnetar XTE J1810--197

    CERN Document Server

    Pintore, F; Mereghetti, S; Esposito, P; Turolla, R; Rea, N; Zelati, F Coti; Israel, G L; Tiengo, A; Zane, S

    2016-01-01

    We have analyzed XMM-Newton and Chandra observations of the transient magnetar XTE J1810-197, spanning more than 11 years, from the initial phases of the 2003 outburst to the current quiescent level. We investigated the evolution of the pulsar spin period and we found evidence for two distinct regimes: during the outburst decay, the spin derivative (nu_dot) was highly variable in the range -(2-4.5)x10^-13 Hz/s, while during quiescence the spin-down rate was more stable at an average value of -1x10^{-13} Hz/s. Only during ~3000 days (from MJD 54165 to MJD 56908) in the quiescent stage, it was possible to find a phase-connected timing solution, with nu_dot = -4.9x10^{-14} Hz/s, and a positive second frequency derivative, nu_dotdot = 1.8x10^{-22} Hz/s. These results are in agreement with the behavior expected if the outburst of XTE J1810-197 was due to a strong magnetospheric twist.

  12. The variable spin-down rate of the transient magnetar XTE J1810-197

    Science.gov (United States)

    Pintore, Fabio; Bernardini, Federico; Mereghetti, Sandro; Esposito, Paolo; Turolla, Roberto; Rea, Nanda; Coti Zelati, Francesco; Israel, Gian Luca; Tiengo, Andrea; Zane, Silvia

    2016-05-01

    We have analysed XMM-Newton and Chandra observations of the transient magnetar XTE J1810-197 spanning more than 11 yr, from the initial phases of the 2003 outburst to the current quiescent level. We investigated the evolution of the pulsar spin period and we found evidence for two distinct regimes: during the outburst decay, dot{ν } was highly variable in the range -(2-4.5) × 10-13 Hz s-1, while during quiescence the spin-down rate was more stable at an average value of -1 × 10-13 Hz s-1. Only during ˜3000 d (from MJD 54165 to MJD 56908) in the quiescent stage it was possible to find a phase-connected timing solution, with dot{ν }=-4.9× 10^{-14} Hz s-1, and a positive second frequency derivative, ddot{ν }=1.8× 10^{-22} Hz s-2. These results are in agreement with the behaviour expected if the outburst of XTE J1810-197 was due to a strong magnetospheric twist.

  13. Phonon Density of States and Heat Capacity of La3-xTe4

    International Nuclear Information System (INIS)

    The phonon density of states (DOS) of La3-xTe4 compounds (x=0.0, 0.18, 0.32) was measured at 300, 520, and 780 K, using inelastic neutron scattering. A significant stiffening of the phonon DOS, and a large broadening of features were observed upon introduction of vacancies on La sites (increasing x). Heat capacity measurements were performed at temperatures ∼1.85 ≤ T ≤ 1200 K and were analyzed to quantify the contributions of phonons and electrons. The Debye temperature and the electronic coefficient of heat capacity determined from these measurements are consistent with the neutron scattering results, and with previously reported first-principles calculations. Our results indicate that La vacancies in La3-xTe4 strongly scatter phonons, and this source of scattering appears to be independent of temperature. The stiffening of the phonon DOS induced by the introduction of vacancies is explained in terms of the electronic structure and the change in bonding. The temperature dependence of the phonon DOS is captured satisfactorily by the quasiharmonic approximation.

  14. Multi-state observations of the Galactic Black Hole XTE J1752-223: Evidence for an intermediate black hole spin

    CERN Document Server

    Reis, R C; Fabian, A C; Cackett, E M; Maitra, D; Reynolds, C S; Rupen, M; Steeghs, D T H; Wijnands, R

    2010-01-01

    The Galactic Black hole candidate XTE J1752-223 was observed during the decay of its 2009 outburst with the Suzaku and XMM-Newton observatories. The observed spectra are consistent with the source being in the ''intermediate`` and ''low-hard state`` respectively. The presence of a strong, relativistic iron emission line is clearly detected in both observations and the line profiles are found to be remarkably consistent and robust to a variety of continuum models. This strongly points to the compact object in \\j\\ being a stellar-mass black hole accretor and not a neutron star. Physically-motivated and self-consistent reflection models for the Fe-\\ka\\ emission-line profile and disk reflection spectrum rule out either a non-rotating, Schwarzchild black hole or a maximally rotating, Kerr black hole at greater than 3sigma level of confidence. Using a fully relativistic line function in which the black hole spin parameter is a variable, we have formally constrained the spin parameter to be $0.52\\pm0.11 (1\\sigma)$. ...

  15. Doppler Tomography of XTE J2123-058 and Other Neutron Star LMXBs

    CERN Document Server

    Hynes, R I; Haswell, C A; Casares, J; Zurita, C

    2000-01-01

    We describe Doppler tomography obtained in the 1998 outburst of the neutron star low mass X-ray binary (LMXB) XTE J2123-058. This analysis, and other aspects of phase-resolved spectroscopy, indicate similarities to SW Sex systems, except that anomalous emission kinematics are seen in HeII, whilst phase 0.5 absorption is confined to H alpha. This separation of these effects may provide tighter constraints on models in the LMXB case than is possible for SW Sex systems. We will compare results for other LMXBs which appear to show similar kinematics and discuss how models for the SW Sex phenomenon can be adapted to these systems. Finally we will summarise the limited Doppler tomography performed on the class of neutron star LMXBs as a whole, and discuss whether any common patterns can yet be identified.

  16. On the Nature of XTE J0421+560/CI Cam

    Science.gov (United States)

    Belloni, T.; vandenAncker, M.; Dieters, S.; Fender, R.; Fox, D. W.; Kommers, J. M.; Lewin, W. H. G.; VanParadijs, J.

    1999-01-01

    We present the results of the analysis of RXTE, BATSE and optical/IR data of the 1998 outburst of the x-ray transient system XTE J0421+650. The x-ray outburst shows a very fast decay initial e-folding time approximately 0.5 days, slowing down to about 2.3 days). The X ray spectrum in the 2-25 keV band is thermal, softening considerably during decay. Intrinsic absorption is observed, also strongly variable. A strong iron line at around 6.7 keV is observed. No fast time variability is observed (CI cam is of a similar nature. The presence of strong radio emission during outburst indicates that the compact object could be a black hole.

  17. AgGaSe2xTe2(1-x) solid solutions

    International Nuclear Information System (INIS)

    Large-block crystals of the ternary compounds AgGaTe2, AgGaSe2 and solid solutions AgGaSe2xTe2(1-x) were grown by the Bridgman method (flat variation). The composition of the prepared crystals was determined by microprobe X-ray spectral analysis, the structure and lattice parameters - by X-ray diffraction. The temperatures of phase transformations were examined by differential thermal analysis, the phase diagram of the AgGaTe2 - AgGaSe2 system was constructed and its thermodynamic analysis was performed. The microhardness (H) of the pointed compounds and solid solutions was measured and its concentration dependence was constructed. It is shown that the curve has maximum

  18. XTE J1739-302 An Unusual New X-ray Transient

    CERN Document Server

    Smith, D M; Marshall, F; Swank, J H; Heindl, W A; Leventhal, M; in 't Zand, J J M; Heise, J

    1998-01-01

    A new x-ray transient, designated XTE J1739-302, was discovered with the Proportional Counter Array (PCA) on the Rossi X-ray Timing Explorer (RXTE) in data from 12 August 1997. Although it was the brightest source in the Galactic Center region while active (about 3.0 x 10^-9 ergs/cm2/s from 2 to 25 keV), it was only observed on that one day; it was not detectable nine days earlier or two days later. There is no known counterpart at other wavelengths, and its proximity to the Galactic Center will make such an identification difficult due to source confusion and extinction. The x-ray spectrum and intensity suggest a giant outburst of a Be/neutron star binary, although no pulsations were observed and the outburst was shorter than is usual from these systems.

  19. The formation of thermally evaporated stable Schottky barriers on p-ZnxPb(1-x)Te thin films

    Science.gov (United States)

    Khairnar, U. P.; Jadhav, S. R.

    2013-06-01

    Metal-semiconductor contacts are drawing increasing attention due to their potential for applications in devices and integrated circuits. Experimentally, lower barrier heights have been reported more often for metallic contacts on p-type semiconductors. Here we report our results regarding barrier heights of Ag/Au on p-ZnxPb(1-x)Te. The barrier heights can be perceived using data on the interface reaction and the phase formation in direct contacts with ZnxPb(1-x)Te. In such contacts which are normally thought to be responsible for the observation of low barrier heights on p-type semiconductor. Thermally stable Ag/Au-contacts with a barrier height of 0.56 eV were produced.

  20. Strongly absorbed quiescent X-ray emission from the X-ray transient XTE J0421+56

    CERN Document Server

    Boirin, L; Lumb, D H; Orlandini, M; Schartel, N

    2002-01-01

    We have observed the soft X-ray transient XTE J0421+56 in quiescence with XMM-Newton. The observed spectrum is highly unusual being dominated by a broad feature at 6.5 keV and can be modeled by a strongly absorbed continuum. The spectra of X-ray transients observed so far are normally modeled using Advection Dominated Accretion Flow models, black-bodies, power-laws, or by the thermal emission from a neutron star surface. The strongly absorbed X-ray emission of XTE J0421+56 could result from the compact object being embedded within the dense circumstellar wind emitted from the supergiant B[e] companion star.

  1. Effect of structure and phase composition on the properties of BixSb2-xTe3 films

    International Nuclear Information System (INIS)

    Investigation into structures and phase composition of BixSb2-xTe-3 films, into dependence of KT tensosensitivity coefficient, resistance temperature coefficient (RTC) on thermodynamic parameters of film production and substrate type, as well as, investigation into effect of doping of BixSb2-xTex film initial batch by acceptor impurities on Rt and RTC represent the aim of the paper

  2. Radio Disappearance of the Magnetar XTE J1810-197 and Continued X-ray Timing

    Science.gov (United States)

    Camilo, F.; Ransom, S. M.; Halpern, J. P.; Alford, J. A. J.; Cognard, I.; Reynolds, J. E.; Johnston, S.; Sarkissian, J.; van Straten, W.

    2016-04-01

    We report on timing, flux density, and polarimetric observations of the transient magnetar and 5.54 s radio pulsar XTE J1810-197 using the Green Bank, Nançay, and Parkes radio telescopes beginning in early 2006, until its sudden disappearance as a radio source in late 2008. Repeated observations through 2016 have not detected radio pulsations again. The torque on the neutron star, as inferred from its rotation frequency derivative \\dot{ν }, decreased in an unsteady manner by a factor of three in the first year of radio monitoring, until approximately mid-2007. By contrast, during its final year as a detectable radio source, the torque decreased steadily by only 9%. The period-averaged flux density, after decreasing by a factor of 20 during the first 10 months of radio monitoring, remained relatively steady in the next 22 months, at an average of 0.7 ± 0.3 mJy at 1.4 GHz, while still showing day-to-day fluctuations by factors of a few. There is evidence that during this last phase of radio activity the magnetar had a steep radio spectrum, in contrast to earlier flat-spectrum behavior. No secular decrease presaged its radio demise. During this time, the pulse profile continued to display large variations; polarimetry, including of a new profile component, indicates that the magnetic geometry remained consistent with that of earlier times. We supplement these results with X-ray timing of the pulsar from its outburst in 2003 up to 2014. For the first 4 years, XTE J1810-197 experienced non-monotonic excursions in frequency derivative by at least a factor of eight. But since 2007, its \\dot{ν } has remained relatively stable near its minimum observed value. The only apparent event in the X-ray record that is possibly contemporaneous with the radio shutdown is a decrease of ≈20% in the hot-spot flux in 2008-2009, to a stable, minimum value. However, the permanence of the high-amplitude, thermal X-ray pulse, even after the (unexplained) radio demise, implies

  3. VLT spectroscopy of XTE J2123-058 during quiescence: the masses of the two components

    Science.gov (United States)

    Casares, J.; Dubus, G.; Shahbaz, T.; Zurita, C.; Charles, P. A.

    2002-01-01

    We present Very Large Telescope (VLT) low-resolution spectroscopy of the neutron star X-ray transient XTE J2123-058 during its quiescent state. Our data reveal the presence of a K7V companion which contributes 77 per cent to the total flux at λ6300 and orbits the neutron star at K2=287+/-12kms-1. Contrary to other soft X-ray transients (SXTs), the Hα emission is almost exactly in antiphase with the velocity curve of the optical companion. Using the light-centre technique we obtain K1=140+/-27kms-1 and hence q=K1/K2=M2/M1=0.49+/-0.10. This, combined with a previous determination of the inclination angle (i=73°+/-4°) yields M1=1.55+/-0.31Msolar and M2=0.76+/-0.22Msolar. M2 agrees well with the observed spectral type. Doppler tomography of the Hα emission shows a non-symmetric accretion disc distribution mimicking that seen in SW Sex stars. Although we find a large systemic velocity of - 110+/-8kms-1 this value is consistent with the galactic rotation velocity at the position of J2123-058, and hence a halo origin. The formation scenario of J2123-058 is still unresolved.

  4. The Swift capture of a long X-ray burst from XTE J1701-407

    CERN Document Server

    Linares, Manuel; Wijnands, Rudy; Soleri, Paolo; Degenaar, Nathalie; Curran, Peter A; Starling, Rhaana L C; van der Klis, Michiel

    2008-01-01

    XTE J1701-407 is a new transient X-ray source discovered on June 8th, 2008. More than one month later it showed a rare type of thermonuclear explosion: a long type I X-ray burst. We report herein the results of our study of the spectral and flux evolution during this burst, as well as the analysis of the outburst in which it took place. We find an upper limit on the distance to the source of 6.2 kpc by considering the maximum luminosity reached by the burst. We measure a total fluence of 3.5*10^{-6} erg/cm^2 throughout the ~20 minutes burst duration and a fluence of 2.6*10^{-3} erg/cm^2 during the first two months of the outburst. We show that the flux decay is best fitted by a power law (index ~1.6) along the tail of the burst. Finally, we discuss the implications of the long burst properties, and the presence of a second and shorter burst detected by Swift ten days later, for the composition of the accreted material and the heating of the burning layer.

  5. X-ray/optical observations of XTE J0421+560/CI Cam in quiescence

    CERN Document Server

    Orlandini, M; Frontera, F; Masetti, N; Dal Fiume, D; Orr, A; Piccioni, A; Raimondo, G; Santangelo, A; Valentini, G; Belloni, T

    2000-01-01

    We report on a BeppoSAX observation of the transient X-ray source XTE J0421+560 during quiescence performed ~150 days after the 1998 April outburst. The source had an unabsorbed 0.5-10 keV flux of 6.7x10^{-12} erg/cm2/s and was still remarkably soft with most of the emission below 2 keV. The X-ray spectrum can be fit with the same two-temperature model as the outburst observations. There is evidence for the presence of an Iron emission feature at ~7 keV. We report also on a series of optical observations performed using the 72 cm Teramo-Normale Telescope (TNT) of the Teramo Observatory, and the 1.5 m Loiano Telescope of the Bologna Observatory. The optical spectrum includes very strong Balmer emission lines, He I, [Fe II], and [O I] features. From the observed L_x/Lopt~10^{-3} the quiescent optical emission cannot be due to re-processing of the X-rays, but has to be generated in the optical companion or the circumstellar material. Moreover, the quiescent X-ray luminosity cannot be due to the optical star if i...

  6. Radio disappearance of the magnetar XTE J1810-197 and continued X-ray timing

    CERN Document Server

    Camilo, F; Halpern, J P; Alford, J A J; Cognard, I; Reynolds, J E; Johnston, S; Sarkissian, J; van Straten, W

    2016-01-01

    We report on timing, flux density, and polarimetric observations of the transient magnetar and 5.54 s radio pulsar XTE J1810-197 using the GBT, Nancay, and Parkes radio telescopes beginning in early 2006, until its sudden disappearance as a radio source in late 2008. Repeated observations through 2016 have not detected radio pulsations again. The torque on the neutron star, as inferred from its rotation frequency derivative f-dot, decreased in an unsteady manner by a factor of 3 in the first year of radio monitoring. In contrast, during its final year as a detectable radio source, the torque decreased steadily by only 9%. The period-averaged flux density, after decreasing by a factor of 20 during the first 10 months of radio monitoring, remained steady in the next 22 months, at an average of 0.7+/-0.3 mJy at 1.4 GHz, while still showing day-to-day fluctuations by factors of a few. There is evidence that during this last phase of radio activity the magnetar had a steep radio spectrum, in contrast to earlier be...

  7. First Principles Calculations of Structural, Electronic, Thermodynamic and Thermal Properties of BaxSr1-xTe Ternary Alloys

    Science.gov (United States)

    Chelli, S.; Meradji, H.; Amara Korba, S.; Ghemid, S.; El Haj Hassan, F.

    2014-12-01

    The structural, electronic thermodynamic and thermal properties of BaxSr1-xTe ternary mixed crystals have been studied using the ab initio full-potential linearized augmented plane wave (FP-LAPW) method within density functional theory (DFT). In this approach, the Perdew-Burke-Ernzerhof-generalized gradient approximation (PBE-GGA) was used for the exchange-correlation potential. Moreover, the recently proposed modified Becke Johnson (mBJ) potential approximation, which successfully corrects the band-gap problem was also used for band structure calculations. The ground-state properties are determined for the cubic bulk materials BaTe, SrTe and their mixed crystals at various concentrations (x = 0.25, 0.5 and 0.75). The effect of composition on lattice constant, bulk modulus and band gap was analyzed. Deviation of the lattice constant from Vegard's law and the bulk modulus from linear concentration dependence (LCD) were observed for the ternary BaxSr1-xTe alloys. The microscopic origins of the gap bowing were explained by using the approach of Zunger and co-workers. On the other hand, the thermodynamic stability of these alloys was investigated by calculating the excess enthalpy of mixing, ΔHm as well as the phase diagram. It was shown that these alloys are stable at high temperature. Thermal effects on some macroscopic properties of BaxSr1-xTe alloys were investigated using the quasi-harmonic Debye model, in which the phononic effects are considered.

  8. Non-linear behaviour of XTE J1550-564 during its 1998-1999 outburst, revealed by recurrence analysis

    CERN Document Server

    Suková, Petra

    2016-01-01

    We study the X-ray emission of the microquasar XTE J1550-564 and analyze the properties of its light curves using the recurrence analysis method. The indicators for non-linear dynamics of the accretion flow are found in the very high state and soft state of this source. The significance of deterministic variability depends on the energy band. We discuss the non-linear dynamics of the accretion flow in the context of the disc-corona geometry and propagating oscillations in the accretion flow.

  9. Synthesis and thermophysical properties of solid solutions CuInSe2xTe2(1-x)

    International Nuclear Information System (INIS)

    Large-block crystals of CuInSe2, CuInTe2 ternary compounds and CuInSe2xTe2(1-x) solid solutions were prepared by two-temperature method. It is determined that dependence between thermal expansion coefficient and composition of solid solution is linear and dependence of thermal conductivity has minimum. It is demonstrated that Debye temperature decreases while root-mean-square dynamic displacements of atoms increase in crystal lattice with increasing content of tellurium atoms in solid solutions

  10. Implication of the Observed Spectral Cutoff Energy Evolution in XTE J1550-564

    Science.gov (United States)

    Titarchuk, Lev; Shaposhnikov, Nikolai

    2010-12-01

    The physical mechanisms responsible for the production of non-thermal emission in accreting black holes (BHs) should be imprinted in the observational appearances of the power-law tails in the X-ray spectra from these objects. Phenomenology of different spectral states exhibited by galactic BH binaries allows us to establish the physics of the photon upscattering under different accretion regimes. We revisit the data collected by the Rossi X-ray Timing Explorer from the BH X-ray binary XTE J1550-564 during two periods of X-ray activity in 1998 and 2000 focusing on the behavior of the high-energy cutoff of the power-law part of the spectrum. For the 1998 outburst, the transition from the low-hard state to the intermediate state was accompanied by a gradual decrease in the cutoff energy. This was followed by an extended minimum which then showed an abrupt reversal to a clear increasing trend as the source evolved to the very high and high-soft states. The 2000 outburst showed only the decreasing and extended minimum portions of this pattern. We attribute this difference in the cutoff energy behavior to the different partial contributions of the thermal and non-thermal (bulk motion) Comptonization. Namely, during the 1998 event the higher accretion rate presumably provided more cooling to the Comptonizing media and thus reducing the effectiveness of the thermal upscattering process. Under these conditions, the bulk motion takes a leading role in boosting the input soft photons. Recent Monte Carlo simulations by Laurent & Titarchuk strongly support this scenario.

  11. Constraining jet/disc geometry and radiative processes in stellar black holes XTE J1118+480 and GX 339−4

    NARCIS (Netherlands)

    D. Maitra; S. Markoff; C. Brocksopp; M. Noble; M. Nowak; J. Wilms

    2009-01-01

    We present results from modelling of quasi-simultaneous broad-band (radio through X-ray) observations of the Galactic stellar black hole (BH) transient X-ray binary (XRB) systems XTE J1118+480 and GX 339−4 using an irradiated disc + compact jet model. In addition to quantifying the physical properti

  12. Topological crystalline insulator PbxSn1-xTe thin films on SrTiO3 (001 with tunable Fermi levels

    Directory of Open Access Journals (Sweden)

    Hua Guo

    2014-05-01

    Full Text Available In this letter, we report a systematic study of topological crystalline insulator PbxSn1-xTe (0 < x < 1 thin films grown by molecular beam epitaxy on SrTiO3(001. Two domains of PbxSn1-xTe thin films with intersecting angle of α ≈ 45° were confirmed by reflection high energy diffraction, scanning tunneling microscopy, and angle-resolved photoemission spectroscopy (ARPES. ARPES study of PbxSn1-xTe thin films demonstrated that the Fermi level of PbTe could be tuned by altering the temperature of substrate whereas SnTe cannot. An M-shaped valance band structure was observed only in SnTe but PbTe is in a topological trivial state with a large gap. In addition, co-evaporation of SnTe and PbTe results in an equivalent variation of Pb concentration as well as the Fermi level of PbxSn1-xTe thin films.

  13. Cd{sub 1−x}Mn{sub x}Te ultrasmall quantum dots growth in a silicate glass matrix by the fusion method

    Energy Technology Data Exchange (ETDEWEB)

    Dantas, Noelio Oliveira; Lima Fernandes, Guilherme de; Almeida Silva, Anielle Christine [Laboratório de Novos Materiais Isolantes e Semicondutores (LNMIS), Instituto de Física, Universidade Federal de Uberlândia, 38408-100 Uberlândia, MG (Brazil); Baffa, Oswaldo; Gómez, Jorge Antônio [Departamento de Física, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, 14040-901 Ribeirão Preto, SP (Brazil)

    2014-09-29

    In this study, we synthesized Cd{sub 1−x}Mn{sub x}Te ultrasmall quantum dots (USQDs) in SiO{sub 2}-Na{sub 2}CO{sub 3}-Al{sub 2}O{sub 3}-B{sub 2}O{sub 3} glass system using the fusion method. Growth of these Cd{sub 1−x}Mn{sub x}Te USQDs was confirmed by optical absorption, atomic force microscopy (AFM), magnetic force microscopy (MFM), scanning transmission electron microscopy (TEM), and electron paramagnetic resonance (EPR) measurements. The blueshift of absorption transition with increasing manganese concentration gives evidence of incorporation of manganese ions (Mn{sup 2+}) in CdTe USQDs. AFM, TEM, and MFM confirmed, respectively, the formation of high quality Cd{sub 1−x}Mn{sub x}Te USQDs with uniformly distributed size and magnetic phases. Furthermore, EPR spectra showed six lines associated to the S = 5/2 spin half-filled d-state, characteristic of Mn{sup 2+}, and confirmed that Mn{sup 2+} are located in the sites core and surface of the CdTe USQD. Therefore, synthesis of high quality Cd{sub 1−x}Mn{sub x}Te USQDs may allow the control of optical and magnetic properties.

  14. Detection of a large Be circumstellar disk during X-ray quiescence of XTE J1946+274

    CERN Document Server

    Arabaci, M Ozbey; Gutierrez-Soto, J; Zurita, C; Nespoli, E; Suso, J; Kiaeerad, F; Garcia-Rojas, J; Kiziloglu, U

    2014-01-01

    We present a multiwavelength study of the Be/X-ray binary system XTE J1946+274 with the main goal of better characterizing its behavior during X-ray quiescence. We aim to shed light on the mechanism which triggers the X-ray activity for this source. XTE J1946+274 was observed by Chandra-ACIS during quiescence in 2013 March 12. In addition, this source has been monitored from the ground-based astronomical observatories of El Teide (Tenerife, Spain), Roque de los Muchachos (La Palma, Spain) and Sierra Nevada (Granada, Spain) since 2011 September, and from the TUBITAK National Observatory (Antalya, Turkey) since 2005 April. We have performed spectral and photometric temporal analyses in order to investigate the quiescent state and transient behavior of this binary system. In 2006, a long mass ejection event took place from the Be star, lasting for about seven years. We also found that a large Be circumstellar disk was present during quiescence, although major X-ray activity was not observed. We made an attempt t...

  15. Reflection Spectroscopy of the Black Hole Binary XTE J1752-223 in the Bright Hard State

    Science.gov (United States)

    Garcia, Javier; Steiner, James F.; Grinberg, Victoria; McClintock, Jeffrey E.; Dauser, Thomas; Remillard, Ronald A.

    2016-04-01

    During its rise to maximum in 2009, XTE J1752-223 stalled for a full month in the bright hard state at about 30% of its peak (Eddington) luminosity. Along this extended period, 60 RXTE pointed observations showed the luminosity and hardness ratio of the source to be extraordinarily stable, resulting in a unique data set of exceptional quality. We combined all these 300 ks of RXTE data into a single PCA (3-45 keV) spectrum with 82 million counts and a single HEXTE spectrum (20-250 keV) with 10.4 million counts. Using our calibration tools PCACORR and HEXBCORR, we greatly enhanced the sensitivity of the detectors to faint spectral features, such as the Fe line and edge. Fitting the PCA+HEXTE spectrum using an advanced version of our reflection code, which includes a physical model of Comptonization, we constrained: the spin of the black hole (or alternatively the inner radius of the accretion disk); the inclination of the system; the ionization state and Fe abundance of the disk's atmosphere; and the temperature and optical depth of the corona. We compare these results with similar ones we reported earlier for GX 339-4 in the bright hard state. XTE J1752-223 and GX 339-4 are the first two of 29 black hole binaries we propose to study using recalibrated RXTE archival data and our reflection models.

  16. Prediction of an arc-tunable Weyl Fermion metallic state in MoxW1-xTe2

    Science.gov (United States)

    Chang, Tay-Rong; Xu, Su-Yang; Chang, Guoqing; Lee, Chi-Cheng; Huang, Shin-Ming; Wang, Baokai; Bian, Guang; Zheng, Hao; Sanchez, Daniel S.; Belopolski, Ilya; Alidoust, Nasser; Neupane, Madhab; Bansil, Arun; Jeng, Horng-Tay; Lin, Hsin; Zahid Hasan, M.

    2016-02-01

    A Weyl semimetal is a new state of matter that hosts Weyl fermions as emergent quasiparticles. The Weyl fermions correspond to isolated points of bulk band degeneracy, Weyl nodes, which are connected only through the crystal's boundary by exotic Fermi arcs. The length of the Fermi arc gives a measure of the topological strength, because the only way to destroy the Weyl nodes is to annihilate them in pairs in the reciprocal space. To date, Weyl semimetals are only realized in the TaAs class. Here, we propose a tunable Weyl state in MoxW1-xTe2 where Weyl nodes are formed by touching points between metallic pockets. We show that the Fermi arc length can be changed as a function of Mo concentration, thus tuning the topological strength. Our results provide an experimentally feasible route to realizing Weyl physics in the layered compound MoxW1-xTe2, where non-saturating magneto-resistance and pressure-driven superconductivity have been observed.

  17. THE VARIABLE QUIESCENT X-RAY EMISSION OF THE TRANSIENT NEUTRON STAR XTE J1701-462

    International Nuclear Information System (INIS)

    We present the results of continued monitoring of the quiescent neutron star low-mass X-ray binary XTE J1701-462 with Chandra and Swift. A new Chandra observation from 2010 October extends our tracking of the neutron star surface temperature from ≅800 days to ≅1160 days since the end of an exceptionally luminous 19 month outburst. This observation indicates that the neutron star crust may still be slowly cooling toward thermal equilibrium with the core; another observation further into quiescence is needed to verify this. The shape of the overall cooling curve is consistent with that of a broken power law, although an exponential decay to a constant level cannot be excluded with the present data. To investigate possible low-level activity, we conducted a monitoring campaign of XTE J1701-462 with Swift during 2010 April-October. Short-term flares-presumably arising from episodic low-level accretion-were observed up to a luminosity of ∼1 x 1035 erg s-1, ∼20 times higher than the normal quiescent level. We conclude that flares of this magnitude are not likely to have significantly affected the equilibrium temperature of the neutron star and are probably not able to have a measurable impact on the cooling curve. However, it is possible that brighter and longer periods of low-level activity have had an appreciable effect on the equilibrium temperature.

  18. Characterizing Intermittency of 4-Hz Quasi-periodic Oscillation in XTE J1550-564 using Hilbert-Huang Transform

    CERN Document Server

    Su, Yi-Hao; Hu, Chin-Ping; Yang, Ting-Chang

    2015-01-01

    We present the time-frequency analysis results based on the Hilbert-Huang transform (HHT) for the evolution of a 4-Hz low-frequency quasi-periodic oscillation (LFQPO) around the black hole X-ray binary XTE J1550-564. The origin of LFQPOs is still debated. To understand the cause of the peak broadening, we utilized a recently developed time-frequency analysis, HHT, for tracking the evolution of the 4-Hz LFQPO from XTE J1550 564. By adaptively decomposing the ~4-Hz oscillatory component from the light curve and acquiring its instantaneous frequency, the Hilbert spectrum illustrates that the LFQPO is composed of a series of intermittent oscillations appearing occasionally between 3 Hz and 5 Hz. We further characterized this intermittency by computing the confidence limits of the instantaneous amplitudes of the intermittent oscillations, and constructed both the distributions of the QPO's high and low amplitude durations, which are the time intervals with and without significant ~4-Hz oscillations, respectively. ...

  19. Emission geometry, radiation pattern, and magnetic topology of the magnetar XTE J1810-197 in its quiescent state

    CERN Document Server

    Bernardini, Federico; Gotthelf, Eric; Israel, Gian Luca; Rea, Nanda; Stella, Luigi

    2011-01-01

    The return to the quiescent state of the Anomalous X-ray pulsar XTE J1810-197 following its 2003 outburst represents a unique opportunity to probe the surface emission properties of a magnetar. The quiescent emission of XTE J1810-197 is composed of two thermal components, one arising from the whole star surface, and the other from a small warm spot on it. By modeling the magnitude and shape of the pulse profile in narrow spectral bands, we have been able to constrain the physical characteristics and geometrical parameters of the system: the two angles that the line of sight and the spin axis make with respect to the warm spot axis (\\psi\\ and \\xi\\ respectively), the angular size of the spot, and the overall surface temperature distribution. Our modeling accounts for the general relativistic effects of gravitational redshift and light bending near the stellar surface, and allows for local anisotropic emission. We found that the surface temperature distribution on the neutron star is consistent with the expectat...

  20. Prediction of an arc-tunable Weyl Fermion metallic state in Mo(x)W(1-x)Te2.

    Science.gov (United States)

    Chang, Tay-Rong; Xu, Su-Yang; Chang, Guoqing; Lee, Chi-Cheng; Huang, Shin-Ming; Wang, BaoKai; Bian, Guang; Zheng, Hao; Sanchez, Daniel S; Belopolski, Ilya; Alidoust, Nasser; Neupane, Madhab; Bansil, Arun; Jeng, Horng-Tay; Lin, Hsin; Zahid Hasan, M

    2016-01-01

    A Weyl semimetal is a new state of matter that hosts Weyl fermions as emergent quasiparticles. The Weyl fermions correspond to isolated points of bulk band degeneracy, Weyl nodes, which are connected only through the crystal's boundary by exotic Fermi arcs. The length of the Fermi arc gives a measure of the topological strength, because the only way to destroy the Weyl nodes is to annihilate them in pairs in the reciprocal space. To date, Weyl semimetals are only realized in the TaAs class. Here, we propose a tunable Weyl state in Mo(x)W(1-x)Te2 where Weyl nodes are formed by touching points between metallic pockets. We show that the Fermi arc length can be changed as a function of Mo concentration, thus tuning the topological strength. Our results provide an experimentally feasible route to realizing Weyl physics in the layered compound Mo(x)W(1-x)Te2, where non-saturating magneto-resistance and pressure-driven superconductivity have been observed. PMID:26875819

  1. Searches for continuous gravitational waves from Scorpius X-1 and XTE J1751-305 in LIGO's sixth science run

    CERN Document Server

    Meadors, Grant David; Riles, Keith; Creighton, Teviet; Robinet, Florent

    2016-01-01

    Scorpius X-1 (Sco X-1) and X-ray transient (XTE) J1751-305 are Low-Mass X-ray Binaries (LMXBs) that may emit continuous gravitational waves detectable in the band of ground-based interferometric observatories. Neutron stars in LMXBs could reach a torque-balance steady-state equilibrium in which angular momentum addition from infalling matter from the binary companion is balanced by angular momentum loss, conceivably due to gravitational-wave emission. Torque-balance predicts a scale for detectable gravitational-wave strain based on observed X-ray flux. This paper describes a search for Sco X-1 and XTE J1751-305 in LIGO Science Run 6 data using the TwoSpect algorithm, based on searching for orbital modulations in the frequency domain. While no detections are claimed, the most stringent upper limits to date on continuous gravitational-wave emission from Sco X-1 are obtained, spanning gravitational wave frequencies from 40 to 2040 Hz and projected semi-major axes from 0.90 to 1.98 light-seconds. At optimal strai...

  2. The Low Quiescent X-Ray Luminosity of the Neutron Star Transient XTE J2123-058

    CERN Document Server

    Tomsick, J A; Halpern, J P; Kaaret, Philip

    2004-01-01

    We report on the first X-ray observations of the neutron star soft X-ray transient (SXT) XTE J2123-058 in quiescence, made by Chandra and BeppoSAX, as well as contemporaneous optical observations. In 2002, the Chandra spectrum of XTE J2123-058 is consistent with a power-law model, or the combination of a blackbody plus a power-law, but it is not well-described by a pure blackbody. Using the interstellar column density, the power-law fit gives photon index of 3.1 (+0.7,-0.6) and indicates a 0.3-8 keV unabsorbed luminosity of 9(+4,-3)E31 (d/8.5 kpc)^2 ergs/s (90% confidence errors). Fits with models consisting of thermal plus power-law components indicate that the upper limit on the temperature of a 1.4 solar mass, 10 km radius neutron star with a hydrogen atmosphere is kT_eff ~ 70 years.

  3. An inhomogeneous lepto-hadronic model for the radiation of relativistic jets. Application to XTE J1118+480

    CERN Document Server

    Vila, Gabriela S; Casco, Nicolás A

    2011-01-01

    Conceptually reconstructing the physical conditions in relativistic jets, given the observed electromagnetic spectrum, poses a complex inverse problem. We aim to obtain a better understanding of the mechanisms operating in relativistic jets through the modeling of their broadband electromagnetic spectrum. We develop an inhomogeneous jet model where the injection of relativistic primary and secondary particles takes place in a spatially extended region. We calculate the contribution of all particles species to the jet emissivity due to several processes, and assess the effect of gamma-ray absorption in internal and external photon fields. A number of specific models with different parameters are computed to explore the possibilities of this scenario. We obtain a variety of spectral shapes depending on the model parameters, some of them predicting significant gamma-ray emission. The observed broadband spectrum of the low-mass microquasar XTE J1118+480 can be satisfactorily reproduced by the model. Our results i...

  4. Quasi-periodic oscillations discovered in the new X-ray pulsar XTE J1858+034

    CERN Document Server

    Paul, B

    1998-01-01

    We report the discovery of low frequency quasi-periodic oscillations centered at 0.11 Hz in the newly discovered 221 s X-ray pulsar XTE J1858+034. Among about 30 known transient X-ray pulsars this is the sixth source in which QPOs have been observed. If the QPOs are produced because of inhomogeneities in the accretion disk at the magnetospheric boundary, the low frequency of the QPOs indicate a large magnetosphere for this pulsar. Both the Keplerian frequency model and the beat frequency model are applicable for production of QPOs in this source. The QPOs and regular pulsations are found to be stronger at higher energy which favours the beat frequency model. The magnetic field of the pulsar is calculated as a function of its distance. The energy spectrum is found to be very hard, consisting of two components, a cut-off power law and an iron fluorescence line.

  5. Depth resolution at profile Auger analysis of the ZnS-PbxSn1-xTe structures

    International Nuclear Information System (INIS)

    The reasons have been studied of anomalously large broadening of profiles at the interface at profile Auger-analysis of the structures ZnS-PbxSn1-xTe, grown by a moleclar-beam epitaxy method. It is shown that this broadening is not related with the existance of the extended region of a valiable composition. Other possible mechanisms of profile persistance have been studied experimentally. In place of the analysis an effectively greater rate of ion etching is observed. It is found that the Auger-profile shape near the interface is determined by the surface relief formation at ion etching. It is shown that the reason of the formation of a developed relief of the surface in the place periodically irradiated by the electron beam during obtaining the Auger-spectra has an electrostatic character. Two possible mechanisms of such relies formation are discussed

  6. The Variable Quiescent X-Ray Emission of the Neutron Star Transient XTE J1701-462

    Science.gov (United States)

    Fridriksson, Joel K.; Homan, J.; Wijnands, R.; Cackett, E. M.; Degenaar, N.; Mendez, M.; Altamirano, D.; Brown, E. F.; Belloni, T. M.; Lewin, W. H. G.

    2011-01-01

    We have monitored the cooling of the neutron star in the transient low-mass X-ray binary XTE J1701-462 with Chandra and XMM-Newton since the source entered quiescence in 2007 after an exceptionally luminous 19-month outburst. A recent Chandra observation made almost 1200 days into quiescence indicates that the neutron star crust is likely still slowly cooling toward thermal equilibrium with the core. The current surface temperature is high compared to other quiescent neutron star transients, with an implied bolometric thermal flux of 5×1033 erg/s. The overall cooling curve seems to have followed a broken power-law shape as predicted by theoretical models, although the observed break is considerably earlier than what is expected from theory. After rapid cooling during the first 200 days of quiescence---strongly indicating a highly conductive neutron star crust---the source unexpectedly showed a large temporary increase in both thermal and non-thermal flux. Prompted by this we conducted a Swift monitoring program of the source during April-October 2010, with short observations taking place once every two weeks. During the program we detected short-term flares up to at least 1×1035 erg/s, a factor of 20 higher than the normal quiescent level. We compare this flaring---presumably arising from episodic low-level accretion---with the behavior observed from faint Galactic transients, and discuss whether flaring in XTE J1701-462 can significantly affect the cooling of the source and whether it can to some extent explain the high temperature of the neutron star core implied by our Chandra observations.

  7. Computer optimization of multispectral solar cells based on GaAs Hg{sub 1-x}Cd{sub x}Te

    Energy Technology Data Exchange (ETDEWEB)

    Rouhani, D.; Esteve, D. [Centre National de la Recherche Scientifique (CNRS), 31 - Toulouse (France); Rouhani, D. [Toulouse-3 Univ., 31 (France); Sylla, A.; Kouadja, K. [Abidjan Univ. (Cote d`Ivoire)

    1995-12-31

    The performances of the monolithic two solar cells tandem is studied. The geometrical and physical parameters of the two cells connected in series are determined for the optimal operation of the device. The chemical composition of the infra red sensitive Hg{sub 1-x}Cd{sub x}Te solar cell is for x = 0.53 with an energy gap of 0.6 eV. The maximum efficiency of the tandem under AM1 solar radiation has been found to be 30 % with contributions of 25 % and 5% for the GaAs and Hg{sub 1-w}Cd{sub x}Te solar cells, respectively. However, sophisticated technologies are needed to achieve this efficiency. (author) 12 refs.

  8. Stimulated emission of free excitons in Cd{sub 1-x}Mn{sub x}Te under nonresonant two-photon excitation

    Energy Technology Data Exchange (ETDEWEB)

    Jang, J.I. [Department of Physics and Astronomy, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208 (United States)], E-mail: joon-jang@northwestern.edu; Mani, S.; Ketterson, J.B. [Department of Physics and Astronomy, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208 (United States); Park, H.Y. [Department of Semiconductor Applications, Ulsan College, San 29 Mugeo Dong, Ulsan 680-749 (Korea, Republic of)], E-mail: hypark@mail.uc.ac.kr

    2008-08-25

    We report on free excitons coexisting with exciton magnetic polarons (EMPs) in bulk semimagnetic semiconductors of Cd{sub 1-x}Mn{sub x}Te for 0.04{<=}x{<=}0.36 at 2 K under nonresonant two-photon excitation. This two-photon excitation not only generates free excitons but also more efficiently creates EMPs compared with ordinary one-photon excitation. Stimulated emission from free excitons is demonstrated under strong two-photon excitation.

  9. Charge Mediated Reversible Metal-Insulator Transition in Monolayer MoTe2 and WxMo1-xTe2 Alloy.

    Science.gov (United States)

    Zhang, Chenxi; Kc, Santosh; Nie, Yifan; Liang, Chaoping; Vandenberghe, William G; Longo, Roberto C; Zheng, Yongping; Kong, Fantai; Hong, Suklyun; Wallace, Robert M; Cho, Kyeongjae

    2016-08-23

    Metal-insulator transitions in low-dimensional materials under ambient conditions are rare and worth pursuing due to their intriguing physics and rich device applications. Monolayer MoTe2 and WTe2 are distinguished from other TMDs by the existence of an exceptional semimetallic distorted octahedral structure (T') with a quite small energy difference from the semiconducting H phase. In the process of transition metal alloying, an equal stability point of the H and the T' phase is observed in the formation energy diagram of monolayer WxMo1-xTe2. This thermodynamically driven phase transition enables a controlled synthesis of the desired phase (H or T') of monolayer WxMo1-xTe2 using a growth method such as chemical vapor deposition (CVD) and molecular beam epitaxy (MBE). Furthermore, charge mediation, as a more feasible method, is found to make the T' phase more stable than the H phase and induce a phase transition from the H phase (semiconducting) to the T' phase (semimetallic) in monolayer WxMo1-xTe2 alloy. This suggests that a dynamic metal-insulator phase transition can be induced, which can be exploited for rich phase transition applications in two-dimensional nanoelectronics. PMID:27415610

  10. MULTIWAVELENGTH OBSERVATIONS OF THE BLACK HOLE TRANSIENT XTE J1752–223 DURING ITS 2010 OUTBURST DECAY

    International Nuclear Information System (INIS)

    Galactic black hole transients show many interesting phenomena during outburst decays. We present simultaneous X-ray (RXTE, Swift, and INTEGRAL), and optical/near-infrared (O/NIR) observations (SMARTS) of the X-ray transient XTE J1752–223 during its outburst decay in 2010. The multiwavelength observations over 150 days in 2010 cover the transition from soft to hard spectral state. We discuss the evolution of radio emission with respect to the O/NIR light curve which shows several flares. One of those flares is bright and long, starting about 60 days after the transition in X-ray timing properties. During this flare, the radio spectral index becomes harder. Other smaller flares occur along with the X-ray timing transition, and also right after the detection of the radio core. We discuss the significances of these flares. Furthermore, using the simultaneous broadband X-ray spectra including INTEGRAL, we find that a high energy cut-off with a folding energy near 250 keV is necessary around the time that the compact jet is forming. The broadband spectrum can be fitted equally well with a Comptonization model. In addition, using photoelectric absorption edges in the XMM-Newton Reflection Grating Spectrometer X-ray spectra and the extinction of red clump giants in the direction of the source, we find a lower limit on the distance of >5 kpc.

  11. Optical studies of the X-ray transient XTE J2123-058; 2, Phase resolved spectroscopy

    CERN Document Server

    Hynes, R I; Haswell, C A; Casares, J; Zurita, C

    1999-01-01

    We present time-resolved spectroscopy of the soft X-ray transient XTE J2123-058 in outburst. Spectral coverage of 3700-6700A was achieved spanning two orbits of the binary. The strongest emission lines are HeII 4686A and CIII/NIII 4640A (Bowen blend). Other weak emission lines of HeII and CIV are present and Balmer lines show a complex structure, possibly contaminated by HeII. HeII 4686A and CIII/NIII 4640A show different orbital light curves indicating an origin in different regions. HeII 4686A profiles show a complex multiple S-wave structure. Doppler tomography reveals this emission is not associated with the companion star, and occurs at velocities too low for Keplerian disk material. It can possibly be associated with overflowing or splashing stream material. The optical spectrum approximates a steep blue power-law, consistent with emission on the Rayleigh-Jeans tail of a black body spectrum. Orbital modulations show no wavelength dependence; this is as expected if both disk and companion star are hot en...

  12. Results of INTEGRAL TOO observation of the transient X-ray burster XTE J1810-189

    CERN Document Server

    Chelovekov, I

    2010-01-01

    We report results of the INTEGRAL Target of Opportunity observations of the transient X-ray burster XTE J1810-189. The observations were performed on April 3--6, 2008, soon after the discovery of the source and near the peak of its outburst. That time the source had a flux of about 50 mCrab and exhibited a hard Comptonized X-ray spectrum extending well above 100 keV. Being approximated by a power law with an exponetial cut-off in the broad 3--100 keV energy band it gave the average photon index $\\Gamma\\simeq 1.6$ and $kT_{cutoff}\\simeq 67$ keV. We found only slight indications for changes in the index during the observation ($\\Gamma$ first steady decreased from $\\sim 2.0$ to $\\sim1.3$ and then increased back to $\\sim 2.0$). However the $N_{\\rmn H}$ value measured by absorption in the low energy part of the spectrum changed drastically and very irregularly (from $\\sim 4\\times 10^{22}$ till $\\sim 100\\times 10^{22}$ cm$^{-2}$). There were 10 type I X-ray bursts detected from the source during these TOO observati...

  13. An XMM-Newton view of the dipping low-mass X-ray binary XTE J1710-281

    CERN Document Server

    Younes, G; Sabra, B

    2009-01-01

    (abridged) We analyzed the archived XMM-Newton observation of the poorly studied low-mass X-ray binary XTE J1710-281 performed in 2004 that covered one orbital period of the system (3.8 hr). The source shows dips as well as eclipses, hence it is viewed close to edge-on. We modeled the spectral changes between persistent and dips in the framework of the partial covering model and the ionized absorber approach. The persistent spectrum can be fit by a power law with a photon index of 1.94(+-0.02) affected by absorption from cool material with a hydrogen column density of 0.401(+-0.007)*10^22 cm^-2. The spectral changes from persistent to deep-dipping intervals are consistent with the partial covering of the power-law emission, with the covering fraction increasing from 26% during shallow dipping to 78% during deep dipping. We do not detect any absorption lines from highly ionized species such as FeXXV. The upper-limits we derive on their equivalent width (EW) are not constraining. Despite not detecting any signa...

  14. Variable Quasi Periodic Oscillations during an Outburst of the Transient X-ray Pulsar XTE J1858 + 034

    Indian Academy of Sciences (India)

    U. Mukherjee; S. Bapna; H. Raichur; B. Paul; S. N. A. Jaaffrey

    2006-03-01

    We have investigated the Quasi Periodic Oscillation (QPO) properties of the transient accreting X-ray pulsar XTE J1858 + 034 during the second outburst of this source in April–May 2004. We have used observations made with the Proportional Counter Array (PCA) of the Rossi X-ray Timing Explorer (RXTE) during May 14–18, 2004, in the declining phase of the outburst. We detected the presence of low frequency QPOs in the frequency range of 140–185 mHz in all the RXTE-PCA observations. We report evolution of the QPO parameters with the time, X-ray flux, and X-ray photon energy. Though a correlation between the QPO centroid frequency and the instantaneous X-ray flux is not very clear from the data, we point out that the QPO frequency and the one day averaged X-ray flux decreased with time during these observations. We have obtained a clear energy dependence of the RMS variation in the QPOs, increasing from about 3% at 3 keV to 6% at 25 keV. The X-ray pulse profile is a single peaked sinusoidal, with pulse fraction increasing from 20% at 3 keV to 45% at 30 keV. We found that, similar to the previous outburst, the energy spectrum is well fitted with amodel consisting of a cut-off power law along with an iron emission line.

  15. An optically thick inner corona geometry for the Very High State Galactic Black Hole XTE J1550-564

    CERN Document Server

    Done, C; Done, Chris; Kubota, Aya

    2005-01-01

    We investigate the accretion disc structure in the strongly Comptonised spectra seen at high luminosities from galactic black holes (variously termed the very high or steep power law dominant state). We use simultaneous ASCA-RXTE data on two such spectra from the black hole transient XTE J1550-564 to constrain the disc and Comptonized luminosity. The broad bandpass of the data gives robust estimates of the disc temperature and luminosity despite the strong Comptonisation distorting the spectrum. The disc temperature is much lower than that seen from the same source at the same luminosity in its disc dominated spectra. This implies that the disc emissivity or/and the disc area has changed between the two states. We build a spectral model of a Comptonising corona over an inner disc to show explicitally that a standard disc emissivity requires a large increase in inner disc radius for the very high state spectra. While such models can describe the spectra, it seems more probable that the disc emissivity changes ...

  16. Long-Term Spectral and Temporal Evolution of Anomalous X-Ray Pulsar XTE J1810-197

    Science.gov (United States)

    Vurgun, Eda; Gogus, Ersin; Chakraborty, Manoneeta; Guver, Tolga

    2016-07-01

    We present spectral and timing studies of the first transient Anomalous X-ray Pulsar XTE J1810-197, a 5.54 s pulsar discovered in 2003, when its X-ray luminosity increased ~100 fold. We investigate the long-term behaviour of the surface temperature,emitting area, and the pulsed fraction. X-ray spectra are well fitted by a two-component blackbody model in which the cool component is most likely arising from the whole surface of star and the hot component is arising from a relatively small hot spot on it. The spectral analysis has also shown evidence for the presence of an absorbtion line feature around 1.2 keV in almost all observations. We fit this absorption feature with an asymmetric gaussian component since it shows an asymmetric structure. The pulse fraction exhibits slightly different temporal evolution in higher and lower energy bands. We will discuss correlative behaviour between the spectral and timing parameters in order to constrain magnetar cooling models.

  17. Teaching "Candide": A Debate.

    Science.gov (United States)

    Braun, Theodore E. D.; And Others

    1988-01-01

    Two different approaches to teaching Voltaire's "Candide", one deriving meaning from the textual fabric or "inside" of the story and the other focusing on the author's "external" intent in writing the story, are presented and compared. (MSE)

  18. RAPID COOLING OF THE NEUTRON STAR IN THE QUIESCENT SUPER-EDDINGTON TRANSIENT XTE J1701-462

    International Nuclear Information System (INIS)

    We present Rossi X-Ray Timing Explorer and Swift observations made during the final three weeks of the 2006-2007 outburst of the super-Eddington neutron star (NS) transient XTE J1701-462, as well as Chandra and XMM-Newton observations covering the first ≅800 days of the subsequent quiescent phase. The source transitioned quickly from active accretion to quiescence, with the luminosity dropping by over 3 orders of magnitude in ≅13 days. The spectra obtained during quiescence exhibit both a thermal component, presumed to originate in emission from the NS surface, and a non-thermal component of uncertain origin, which has shown large and irregular variability. We interpret the observed decay of the inferred effective surface temperature of the NS in quiescence as the cooling of the NS crust after having been heated and brought out of thermal equilibrium with the core during the outburst. The interpretation of the data is complicated by an apparent temporary increase in temperature ≅220 days into quiescence, possibly due to an additional spurt of accretion. We derive an exponential decay timescale of ≅120+30-20 days for the inferred temperature (excluding observations affected by the temporary increase). This short timescale indicates a highly conductive NS crust. Further observations are needed to confirm whether the crust is still slowly cooling or has already reached thermal equilibrium with the core at a surface temperature of ≅125 eV. The latter would imply a high equilibrium bolometric thermal luminosity of ≅5 x 1033ergs-1 for an assumed distance of 8.8 kpc.

  19. Growth and characterization of CdTe single quantum wells confined by Cd 1- xZn xTe alloy and short period CdTe/ZnTe superlattice

    Science.gov (United States)

    Magnea, N.; Lentz, G.; Mariette, H.; Feuillet, G.; Dal'bo, F.; Tuffigo, H.

    1989-02-01

    A comparative study of structural and optical properties of CdTe single quantum wells has been performed. Very efficient CdTe-Cd 1-xZn xTe (x Zn ≤ 0.2) wells have been grown and short period superlattices appear as a promising substitute of the alloy.

  20. The Transient Accereting X-Ray Pulsar XTE J1946+274: Stability of the X-Ray Properties at Low Flux and Updated Orbital Solution

    CERN Document Server

    Marcu-Cheatham, Diana M; Kühnel, Matthias; Müller, Sebastian; Falkner, Sebastian; Caballero, Isabel; Finger, Mark H; Jenke, Peter J; Wilson-Hodge, Colleen A; Fürst, Felix; Grinberg, Victoria; Hemphill, Paul B; Kreykenbohm, Ingo; Klochkov, Dmitry; Rothschild, Richard E; Terada, Yukikatsu; Enoto, Teruaki; Iwakiri, Wataru; Wolff, Michael T; Becker, Peter A; Wood, Kent S; Wilms, Jöern

    2015-01-01

    We present a timing and spectral analysis of the X-ray pulsar XTE J1946+274 observed with Suzaku during an outburst decline in 2010 October and compare with previous results. XTE J1946+274 is a transient X-ray binary consisting of a Be-type star and a neutron star with a 15.75 s pulse period in a 172 d orbit with 2-3 outbursts per orbit during phases of activity. We improve the orbital solution using data from multiple instruments. The X-ray spectrum can be described by an absorbed Fermi-Dirac cutoff power law model along with a narrow Fe K line at 6.4 keV and a weak Cyclotron Resonance Scattering Feature (CRSF) at ~35 keV. The Suzaku data are consistent with the previously observed continuum flux versus iron line flux correlation expected from fluorescence emission along the line of sight. However, the observed iron line flux is slightly higher, indicating the possibility of a higher iron abundance or the presence of non-uniform material. We argue that the source most likely has only been observed in the sub...

  1. The Transient Accreting X-Ray Pulsar XTE J1946+274: Stability of X-Ray Properties at Low Flux and Updated Orbital Solution

    Science.gov (United States)

    Marcu-Cheatham, Diana M.; Pottschmidt, Katja; Kühnel, Matthias; Müller, Sebastian; Falkner, Sebastian; Caballero, Isabel; Finger, Mark H.; Jenke, Peter J.; Wilson-Hodge, Colleen A.; Fürst, Felix; Grinberg, Victoria; Hemphill, Paul B.; Kreykenbohm, Ingo; Klochkov, Dmitry; Rothschild, Richard E.; Terada, Yukikatsu; Enoto, Teruaki; Iwakiri, Wataru; Wolff, Michael T.; Becker, Peter A.; Wood, Kent S.; Wilms, Jörn

    2015-12-01

    We present a timing and spectral analysis of the X-ray pulsar XTE J1946+274 observed with Suzaku during an outburst decline in 2010 October and compare with previous results. XTE J1946+274 is a transient X-ray binary consisting of a Be-type star and a neutron star with a 15.75 s pulse period in a 172 days orbit with 2-3 outbursts per orbit during phases of activity. We improve the orbital solution using data from multiple instruments. The X-ray spectrum can be described by an absorbed Fermi-Dirac cut-off power-law model along with a narrow Fe Kα line at 6.4 keV and a weak Cyclotron Resonance Scattering Feature (CRSF) at ˜35 keV. The Suzaku data are consistent with the previously observed continuum flux versus iron line flux correlation expected from fluorescence emission along the line of sight. However, the observed iron line flux is slightly higher, indicating the possibility of a higher iron abundance or the presence of non-uniform material. We argue that the source most likely has only been observed in the subcritical (non-radiation dominated) state since its pulse profile is stable over all observed luminosities and the energy of the CRSF is approximately the same at the highest (˜5 × 1037 erg s-1) and lowest (˜5 × 1036 erg s-1) observed 3-60 keV luminosities.

  2. Polarized far infrared magnetoplasmon reflectivity of doped Cd{sub x}Mn{sub 1-x}Te semimagnetic semiconductor in the Voigt configuration

    Energy Technology Data Exchange (ETDEWEB)

    Shayesteh, S.F.; Hidari, M. [Department of Physics, University of Guilan, P.O. Box 1914, Rasht (Iran)

    2007-06-15

    Calculations of the p-polarized far infrared magnetoplasmon reflectivity of semimagnetic semiconductor Cd{sub x}Mn {sub 1-x}Te doped ternary alloy in the presence of a magnetic field parallel to the surface of the sample (the Voigt geometry) are used to investigate magnetoplasmon and zone center optical phonon frequencies. It is assumed that the sample is characterized by a dielectric tensor in which the optical phonon contribution and free carriers (plasmon and cyclotron response) are included. The results show that the transverse optical phonon mode is sensitive to the alloy composition, x, and can be used to determine the value of x. The longitudinal optical phonon frequencies are shifted due to phonon-plasmon coupling in doped samples. Also, the influence of composition on the vibrational modes in zinc blende Cd {sub x}Mn {sub 1-x}Te is described within a modified random element isodisplacement (MREI) approach. By indicating the plasmon and cyclotron frequencies from p-polarized reflectivity spectra and the Voigt permittivity, we calculated the carrier concentration and the effective masses of the carriers. Furthermore, we indicate the frequencies of the phonons at the {gamma}, K, X and L high symmetry points of the Brillouin zone based on a microscopic second-neighbor rigid ion model (RIM). (copyright 2007 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  3. Strongly absorbed quiescent X-ray emission from the X-ray transient XTE J0421+56 (CI Cam) observed with XMM-Newton

    CERN Document Server

    Boirin, L; Oosterbroek, T; Lumb, D H; Orlandini, M; Schartel, N

    2002-01-01

    We have observed the X-ray transient XTE J0421+56 in quiescence with XMM-Newton. The observed spectrum is highly unusual being dominated by an emission feature at ~6.5 keV. The spectrum can be fit using a partially covered power-law and Gaussian line model, in which the emission is almost completely covered (covering fraction of 0.98_{-0.06}^{+0.02}) by neutral material and is strongly absorbed with an N_H of (5_{-2}^{+3}) x 10^{23} atom cm^{-2}. This absorption is local and not interstellar. The Gaussian has a centroid energy of 6.4 +/- 0.1 keV, a width < 0.28 keV and an equivalent width of 940 ^{+650}_{-460} eV. It can be interpreted as fluorescent emission line from iron. Using this model and assuming XTE J0421+56 is at a distance of 5 kpc, its 0.5-10 keV luminosity is 3.5 x 10^{33} erg s^{-1}. The Optical Monitor onboard XMM-Newton indicates a V magnitude of 11.86 +/- 0.03. The spectra of X-ray transients in quiescence are normally modeled using advection dominated accretion flows, power-laws, or by th...

  4. Conduction mechanisms in p-type Pb{sub 1-x}Eu{sub x}Te alloys in the insulator regime

    Energy Technology Data Exchange (ETDEWEB)

    Peres, M. L.; Rubinger, R. M.; Ribeiro, L. H.; Rubinger, C. P. L. [Departamento de Fisica e Quimica, Instituto de Ciencias Exatas, Universidade Federal de Itajuba, Itajuba, PB 50, MG CEP 37500-903 (Brazil); Ribeiro, G. M. [Departamento de Fisica, ICEx, Universidade Federal de Minas Gerais, Belo Horizonte, PB 702, MG CEP 30123-970 (Brazil); Chitta, V. A. [Instituto de Fisica, Universidade de Sao Paulo, Sao Paulo, PB 66318, SP CEP 05315-970 (Brazil); Rappl, P. H. O.; Abramof, E. [Laboratorio Associado de Sensores e Materiais, Instituto Nacional de Pesquisas Espaciais, Sao Jose dos Campos, PB 515, SP CEP 12201-970 (Brazil)

    2012-06-15

    Electrical resistivity measurements were performed on p-type Pb{sub 1-x}Eu{sub x}Te films with Eu content x = 4%, 5%, 6%, 8%, and 9%. The well-known metal-insulator transition that occurs around 5% at room temperature due to the introduction of Eu is observed, and we used the differential activation energy method to study the conduction mechanisms present in these samples. In the insulator regime (x > 6%), we found that band conduction is the dominating conduction mechanism for high temperatures with carriers excitation between the valence band and the 4f levels originated from the Eu atoms. We also verified that mix conduction dominates the low temperatures region. Samples with x = 4% and 5% present a temperature dependent metal insulator transition and we found that this dependence can be related to the relation between the thermal energy k{sub B}T and the activation energy {Delta}{epsilon}{sub a}. The physical description obtained through the activation energy analysis gives a new insight about the conduction mechanisms in insulating p-type Pb{sub 1-x}Eu{sub x}Te films and also shed some light over the influence of the 4f levels on the transport process in the insulator region.

  5. Primary and Presidential Candidates

    DEFF Research Database (Denmark)

    Goddard, Joseph

    2012-01-01

    This article looks at primary and presidential candidates in 2008 and 2012. Evidence suggests that voters are less influenced by candidates’ color, gender, or religious observation than previously. Conversely, markers of difference remain salient in the imaginations of pollsters and journalists...

  6. PHOTOIONIZATION MODELING OF OXYGEN K ABSORPTION IN THE INTERSTELLAR MEDIUM: THE CHANDRA GRATING SPECTRA OF XTE J1817-330

    Energy Technology Data Exchange (ETDEWEB)

    Gatuzz, E.; Mendoza, C. [Centro de Fisica, Instituto Venezolano de Investigaciones Cientificas (IVIC), P.O. Box 20632, Caracas 1020A (Venezuela, Bolivarian Republic of); Garcia, J.; Lohfink, A. [Department of Astronomy and Maryland Astronomy Center for Theory and Computation, University of Maryland, College Park, MD 20742 (United States); Kallman, T. R.; Witthoeft, M. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Bautista, M. A. [Department of Physics, Western Michigan University, Kalamazoo, MI 49008 (United States); Palmeri, P.; Quinet, P., E-mail: egatuzz@ivic.gob.ve, E-mail: claudio@ivic.gob.ve, E-mail: javier@astro.umd.edu, E-mail: alohfink@astro.umd.edu, E-mail: timothy.r.kallman@nasa.gov, E-mail: michael.c.witthoeft@nasa.gov, E-mail: manuel.bautista@wmich.edu, E-mail: palmeri@umons.ac.be, E-mail: quinet@umons.ac.be [Astrophysique et Spectroscopie, Universite de Mons-UMONS, B-7000 Mons (Belgium)

    2013-05-01

    We present detailed analyses of oxygen K absorption in the interstellar medium (ISM) using four high-resolution Chandra spectra toward the X-ray low-mass binary XTE J1817-330. The 11-25 A broadband is described with a simple absorption model that takes into account the pile-up effect and results in an estimate of the hydrogen column density. The oxygen K-edge region (21-25 A) is fitted with the physical warmabs model, which is based on a photoionization model grid generated with the XSTAR code with the most up-to-date atomic database. This approach allows a benchmark of the atomic data which involves wavelength shifts of both the K lines and photoionization cross sections in order to fit the observed spectra accurately. As a result we obtain a column density of N{sub H} = 1.38 {+-} 0.01 Multiplication-Sign 10{sup 21} cm{sup -2}; an ionization parameter of log {xi} = -2.70 {+-} 0.023; an oxygen abundance of A{sub O}= 0.689{sup +0.015}{sub -0.010}; and ionization fractions of O I/O = 0.911, O II/O = 0.077, and O III/O = 0.012 that are in good agreement with results from previous studies. Since the oxygen abundance in warmabs is given relative to the solar standard of Grevesse and Sauval, a rescaling with the revision by Asplund et al. yields A{sub O}=0.952{sup +0.020}{sub -0.013}, a value close to solar that reinforces the new standard. We identify several atomic absorption lines-K{alpha}, K{beta}, and K{gamma} in O I and O II and K{alpha} in O III, O VI, and O VII-the last two probably residing in the neighborhood of the source rather than in the ISM. This is the first firm detection of oxygen K resonances with principal quantum numbers n > 2 associated with ISM cold absorption.

  7. Effect of slow electrons on the field dependences of the Hall coefficient for CdxHg1-xTe alloys at T = 77 K

    International Nuclear Information System (INIS)

    An algorithm which allows one to determine the statistic weights and mobilities of free carriers by fitting the calculated dependence of the Hall coefficient on the magnetic field induction R(B) to the experimental data is developed. The model is used for description of the dependences R(B) obtained for the CdxHg1-xTe (x ∼ 0.2) alloy at liquid-nitrogen temperature. It is shown that the experimental data are satisfactorily described by a model which implies the presence of fast and slow electrons in the sample. It is found that the heavier the dependence R(B), the higher the contribution of slow electrons

  8. Cross-correlations between soft and hard light curves depending on luminosity in the transient neutron star XTE J1701-462

    Science.gov (United States)

    Wang, Y. N.; Lei, Y. J.; Ding, G. Q.; Qu, J. L.; Ge, M. Y.; Zhang, C. M.; Chen, L.; Ma, X.

    2014-06-01

    Using all the observations from Rossi X-ray Timing Explorer for the accreting neutron star XTE J1701-462, we carry out a systematic study of the cross-correlation function between its soft and hard light curves. Over the entire outburst, XTE J1701-462 evolves from super-Eddington luminosities to quiescence and shows both Z and atoll behaviours. Following previous work, we divide the outburst into five intervals: one Cyg-like interval, three Sco-like intervals and one atoll interval, according to their different behaviours in the corresponding colour-colour diagrams (CCDs). With cross-correlation analyses, anti-correlation, positive and ambiguous correlations are found in the different intervals in this source. Both anti-correlated soft and hard time lags are detected, where hard lags mean that the hard photons lag behind the soft ones and soft lags mean the reverse. In the Cyg-like interval, anti-correlations are presented in the hard vertex and upper normal branch (NB) and positive correlations dominate the horizontal branch (HB) and lower NB. In the first two Sco-like intervals, anti-correlations are detected first and most of them are found in the HB and/or upper NB, while positive correlations are mostly detected in the lower NB and flaring branch (FB). In the following interval, i.e. the third Sco-like interval, anti-correlations occur on the upper FB and positive correlations are mainly distributed in the lower FB. The different intervals correspond to various luminosities; therefore, the position of anti-correlations in the CCD might depend on the luminosity. It is noted that, in the Cyg-like interval, positive correlations dominate the HB, which is not consistent with the behaviour of the Cyg-like Z sources GX 5-1 and Cyg X-2, the HBs of which host ambiguous correlations and anti-correlations. Hence, for comparison with GX 5-1, we analyse the spectra of the HB and the hard vertex of the Cyg-like interval. The fitting results show that, in contrast to GX 5

  9. Constraints on braneworld gravity models from a kinematic limit on the age of the black hole XTE J1118+480.

    Science.gov (United States)

    Psaltis, Dimitrios

    2007-05-01

    In braneworld gravity models with a finite anti-de Sitter space (AdS) curvature in the extra dimension, the AdS/conformal field theory correspondence leads to a prediction for the lifetime of astrophysical black holes that is significantly smaller than the Hubble time, for asymptotic curvatures that are consistent with current experiments. Using the recent measurements of the position, three-dimensional spatial velocity, and mass of the black hole XTE J1118+480, I calculate a lower limit on its kinematic age of > or =11 Myr (95% confidence). This translates into an upper limit for the asymptotic AdS curvature in the extra dimensions of <0.08 mm, which significantly improves the limit obtained by table top experiments of sub mm gravity. PMID:17501556

  10. Abundancias químicas de la compañera visible del agujero negro binario V4641 Sgr (XTE J1819-254)

    Science.gov (United States)

    Cúneo, V. A.; Jofré, E.; Pintado, O. I.; Gómez, M. N.

    2015-08-01

    In this work we expose an analysis of the chemical abundances of the optical companion of the confirmed black hole binary V4641 Sgr (XTE J1819-254) from GMOS spectra obtained with the Gemini North telescope. This analysis allowed to observe an enhancement of N, O, Mg and Si, attributed to the contamination of heavy elements generated during the supernova explosion that gave birth to the black hole. It was also observed that Cr and Fe were subabundant. The aim of this study is to test the formation scenario of a binary system containing a black hole as remnant of the supernova explosion of a massive star, and to provide information to better understand the final stages in the evolution of massive stars and black hole progenitors.

  11. Spin effects in high- and low-field magnetotransport experiments in semimagnetic Cd{sub 1-x}Mn{sub x}Te heterostructures

    Energy Technology Data Exchange (ETDEWEB)

    Betthausen, Christian

    2012-07-09

    Within the framework of this PhD we report on the very first observation of the fractional Quantum Hall Effect (FQHE) in both, a non-magnetic CdTe and a semimagnetic Cd{sub 1-x}Mn{sub x}Te quantum well device. To our knowledge, this constitutes the first demonstration of this effect in the II-VI material family. Furthermore, our results reveal that the formation of fractional Quantum Hall states is not inhibited by the presence of magnetic impurities in a quantum structure. The second part of this thesis addresses an alternative route to realize efficient spin transistor action. Typically, spin transistor designs relying on spin-orbit interaction principally suffer from low signal levels due to limitations in spin injection efficiency and fast spin decay. Here we present an approach to realize spin transistor action in systems where spin information is protected by propagating it adiabatically. This is achieved by inducing tunable diabatic Landau-Zener transitions that lead to a backscattering of spins and hence allow controlling the transmission of spin-polarized charge carriers through the device, i.e. switching between 'on' and 'off' states. We demonstrate the validity of our approach in a Cd{sub 1-x}Mn{sub x}Te diluted magnetic semiconductor quantum well structure where efficient spin transport is observed over device distances of 50 {mu}m. In contrast to other spin transistor designs we find that our concept is exceptionally tolerant against disorder.

  12. On the Nature of QPO Phase Lags in Black Hole Candidates

    Science.gov (United States)

    Shaposhnikov, Nikolai

    2012-01-01

    Observations of quasi-periodic oscillations (QPOs) in X-ray binaries hold a key to understanding many aspects of these enigmatic systems. Complex appearance of the Fourier phase lags related to QPOs is one of the most puzzling observational effects in accreting black holes. In this Letter we show that QPO properties, including phase lags, can be explained in a framework of a simple scenario, where the oscillating media provides a feedback on the emerging spectrum. We demonstrate that the QPO waveform is presented by the product of a perturbation and a time delayed response factors, where the response is energy dependent. The essential property of this effect is its non-linear and multiplicative nature. Our multiplicative reverberation model successfully describes the QPO components in energy dependent power spectra as well as the appearance of the phase lags between signal in different energy bands. We apply our model to QPOs observed by Rossi X-ray Timing Explorer in BH candidate XTE J1550-564. We briefly discuss the implications of the observed energy dependence of the QPO reverberation times and amplitudes to the nature of the power law spectral component and its variability.

  13. Paramagnetic behavior at room temperature of Zn{sub 1−x}Mn{sub x}Te nanocrystals grown in a phosphate glass matrix by the fusion method

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Alessandra S., E-mail: alessandra@mestrado.ufu.br [Universidade Federal de Uberlândia, Instituto de Física, Laboratório de Novos Materiais Isolantes e Semicondutores (LNMIS), Uberlândia CEP: 38400-902 (Brazil); Franco, Adolfo; Pelegrini, Fernando [Instituto de Física, Universidade Federal de Goiás, C. P. 131, 74001-970 Goiânia, GO (Brazil); Dantas, Noelio O. [Universidade Federal de Uberlândia, Instituto de Física, Laboratório de Novos Materiais Isolantes e Semicondutores (LNMIS), Uberlândia CEP: 38400-902 (Brazil)

    2015-10-25

    This work reports on the synthesis and characterization of Zn{sub 1−x}Mn{sub x}Te nanocrystals (NCs) with Mn doping concentration x varying from 0.000 to 0.800. Physical properties of samples were studied by transmission electron microscopy, magnetic force microscopy, vibrating sample magnetometry and electron paramagnetic resonance spectroscopy. Room temperature experiments revealed the size of NCs, the growth of magnetization and non-linear dependence of magnetic susceptibility on the concentration of Mn{sup 2+} ions; samples with low concentrations revealed the presence of ions in the interior and near the surface of the NCs. The results obtained confirm the paramagnetic behavior of Zn{sub 1−x}Mn{sub x}Te NCs at room temperature.

  14. Electoral Systems and Candidate Selection

    NARCIS (Netherlands)

    Hazan, Reuven Y.; Voerman, Gerrit

    2006-01-01

    Electoral systems at the national level and candidate selection methods at the party level are connected, maybe not causally but they do influence each other. More precisely, the electoral system constrains and conditions the parties' menu of choices concerning candidate selection. Moreover, in ligh

  15. First-principles calculations of a half-metallic ferromagnet zinc blende Zn{sub 1−x}V{sub x}Te

    Energy Technology Data Exchange (ETDEWEB)

    El Amine Monir, M.; Baltache, H. [Laboratoire de Physique Quantique de la Modélisation Mathématique (LPQ3M), Université de Mascara, 29000 (Algeria); Khenata, R., E-mail: khenata_rabah@yahoo.fr [Laboratoire de Physique Quantique de la Modélisation Mathématique (LPQ3M), Université de Mascara, 29000 (Algeria); Murtaza, G. [Materials Modeling Laboratory, Department of Physics, Islamia College University, Peshawar (Pakistan); Azam, Sikander [New Technologies-Research Center, University of West Bohemia, Univerzitni 8, 306 14 Pilsen (Czech Republic); Bouhemadou, A. [Laboratory for Developing New Materials and their Characterization, Department of Physics, Faculty of Science, University Setif 1, 19000 Setif (Algeria); Al-Douri, Y. [Institute of Nano Electronic Engineering, University Malaysia Perlis, 01000 Kangar, Perlis (Malaysia); Bin Omran, S. [Department of Physics and Astronomy, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451 (Saudi Arabia); Ali, Roshan [Materials Modeling Lab, Department of Physics, Post Graduate Jahanzeb College, Swat (Pakistan)

    2015-03-15

    First-principles calculations have been used to study the structural, elastic, electronic, magnetic and thermal properties of zinc blende Zn{sub 1−x}V{sub x}Te for x=0, 0.25, 0.50, 0.75 and 1 using the full-potential linearized augmented plane wave method (FP-LAPW) based on spin-polarized density functional theory (DFT). The electronic exchange-correlation potential is approached using the spin generalized gradient approximation (spin-GGA). The structural properties of the Zn{sub 1−x}V{sub x}Te alloys (x=0, 0.25, 0.50, 0.75 and 1) are given for the lattice constants and the bulk moduli and their pressure derivatives. The elastic constants C{sub 11}, C{sub 12} and C{sub 44} are calculated using numerical first-principles calculations implemented in the WIEN2k package. An analysis of the band structures and the densities of states reveals that Zn{sub 0.50}V{sub 0.50}Te and Zn{sub 0.75}V{sub 0.25}Te exhibit a half-metallic character, while Zn{sub 0.25}V{sub 0.75}Te is nearly half-metallic. The band structure calculations are used to estimate the spin-polarized splitting energies Δ{sub x}(d) and Δ{sub x}(pd) produced by the V(3d)-doped and s(p)–d exchange constants N{sub 0α} (conduction band) and N{sub 0β} (valence band). The p–d hybridization reduces the magnetic moment of V from its atomic charge value of 3µ{sub B} and creates small local magnetic moments on the nonmagnetic Zn and Te sites. Finally, we present the thermal effect on the macroscopic properties of these alloys, such as the thermal expansion coefficient, heat capacity and Debye temperature, based on the quasi-harmonic Debye model. - Highlights: • Some physical properties of Vanadium doped ZnTe have been investigated. • Structural parameters for the parent compounds compare well with the available data. • The elastic and thermal properties are studied for the first time.

  16. XTE J1701-462 and its Implications for the Nature of Subclasses in Low-Magnetic-Field Neutron Star Low-Mass X-Ray Binaries

    CERN Document Server

    Homan, Jeroen; Fridriksson, Joel K; Remillard, Ronald A; Wijnands, Rudy; Mendez, Mariano; Lin, Dacheng; Altamirano, Diego; Casella, Piergiorgio; Belloni, Tomaso; Lewin, Walter H G

    2010-01-01

    We report on an analysis of RXTE data of the transient neutron star low-mass X-ray binary (NS-LMXB) XTE J1701-462, obtained during its 2006-2007 outburst. The X-ray properties of the source changed between those of various types of NS-LMXB subclasses. At high luminosities the source switched between two types of Z source behavior and at low luminosities we observed a transition from Z source to atoll source behavior. These transitions between subclasses primarily manifest themselves as changes in the shapes of the tracks in X-ray color-color and hardness-intensity diagrams, but they are accompanied by changes in the kHz quasi-periodic oscillations, broad-band variability, burst behavior, and/or X-ray spectra. We find that the low-energy X-ray flux is a good parameter to track the gradual evolution of the tracks in color-color and hardness-intensity diagrams, allowing us to resolve the evolution of the source in greater detail than before and relate the observed properties to other NS-LMXBs. We further find th...

  17. Limits on pair production and multi-zone comptonization: The broadband X/gamma-ray spectrum of XTE J1550-564 revisited

    CERN Document Server

    Hjalmarsdotter, L; Done, C

    2015-01-01

    At high luminosities black hole binaries show spectra with a strong disc component accompanied by an equally strong tail where at least some of the electrons are non-thermal. We reanalyze the simultaneous ASCA-RXTE-OSSE data from the 1998 outburst of XTE J1550-564, which span 0.7-1000 keV and remain the best data available of a black hole binary in this state. We reassess the importance of electron-positron pair production using a realistically high value of the source compactness for the first time. The lack of an observable annihilation line together with the observed gamma-ray flux beyond 511 keV constrains the maximum electron Lorentz factor to be leq 10 and the slope of the injected electrons to leq 2.5. We also use the fast (10-50 Hz) variability spectrum to constrain the spatial dependence of the electron heating and acceleration. We find that the spectrum of the fast variability is consistent with being fully thermal, so that the observed non-thermal emission is produced from further out in the flow.

  18. Accretion flow behaviour during the evolution of the Quasi Periodic Oscillation Frequency of XTE J1550-564 in 1998 outburst

    CERN Document Server

    Chakrabarti, Sandip K; Pal, P S

    2009-01-01

    Low and intermediate frequency quasi-periodic oscillations (QPOs) are thought to be due to oscillations of Comptonizing regions or hot regions embedded in Keplerian discs. Observational evidence of evolutions of QPOs would therefore be very important as they throw lights on the dynamics of the hotter region. Our aim is to find systems in which there is a well-defined correlation among the frequencies of the QPOs over a range of time so as to understand the physical picture. In this paper, we concentrate on the archival data of XTE J1550-564 obtained during 1998 outburst, and study the systematic drifts during the rising phase from the 1998 September 7 to the 1998 September 19, when the QPO frequency increased monotonically from 81mHz to 13.1Hz. Immediately after that, QPO frequency started to decrease and on the 1998 September 26, the QPO frequency became 2.62Hz. After that, its value remained almost constant. This frequency drift can be modelled satisfactorily with a propagatory oscillating shock solution wh...

  19. Electrical conduction mechanism in Se90-xTe5Sn5Inx (x = 0, 3, 6 and 9 multi-component glassy alloys

    Directory of Open Access Journals (Sweden)

    Indra Sen Ram

    2015-08-01

    Full Text Available Electrical conductivity of Se90-xTe5Sn5Inx (x = 0, 3, 6 and 9 glassy systems was studied employing impedance spectroscopic technique in the frequency range 100 Hz to 1 MHz and in the temperature range 308-388 K. The DC conductivity (σdc at each temperature was evaluated from the low frequency plateau region for all the samples under investigation. The bulk conductivity for each sample was also evaluated from Nyquist impedance plots. The semicircle shape of Nyquist plot exhibit dipolar nature of samples. The activation energy for glassy, amorphous and crystalline region from the Arrhenius plot of the DC conductivity and bulk conductivity was evaluated. From the results it is found that activation energy varied from 0.091 to 0.194 eV in glassy, 0.686 to 0.002 eV in amorphous and 0.215 to 0.503 eV in crystalline region. The activation energy (ΔE from DC conductivity and bulk conductivity found to be close in corresponding regions. The pre-exponential factor was also calculated for all three regions.

  20. XTE J1859+226: Evolution of spectro-temporal properties, disk-jet connection during 1999 outburst and implications on accretion disk dynamics

    CERN Document Server

    D, Radhika

    2013-01-01

    We investigated the `spectro-temporal' behaviour of the source XTE J1859+226 in X-rays during its outburst phase in 1999, by revisiting the RXTE PCA/HEXTE data in 3 - 150 keV spectral band. Detailed analysis shows that the source evolves through different spectral states during its entire outburst as indicated by the variation in the temporal and spectral features. Evolution of QPO frequencies during rising phase, modeled with propagating oscillatory shock gives an estimate of the oscillating region(corona). Although the evolution pattern of the outburst followed the typical q-shaped profile, we observe an absence of `canonical' soft state and a weak presence of `secondary' emission during the decay phase of the outburst. The broad band spectra, modeled with high energy cutoff, show that fold-energy increases monotonically in the hard and hard-intermediate states followed by a random variation in the soft-intermediate state. These findings make the source evolution more complex. It is also observed that durin...

  1. Cross-correlations between soft and hard light curves depending on luminosity in the transient neutron star XTE J1701-462

    CERN Document Server

    Wang, Ya-Nan; Ding, Guo-Qiang; Qu, Jin-Lu; Ge, Ming-Yu; Zhang, Cheng-Min; Ma, Xiang; Chen, Li

    2014-01-01

    Using all the observations from Rossi X-ray Timing Explorer for accreting neutron star XTE J1701-462, we carry out a systematic study on the cross-correlation between its soft and hard light curves. The anti-correlations appear at the hard vertex and on the upper normal branch (NB) in the Cyg-like interval, occur on the horizontal branch (HB) and/or upper NB in the first and second Sco-like intervals, and display at the upper flaring branch (FB) in the third Sco-like interval. We suggest that the anti-correlation might evolve with luminosity, because with decreasing of luminosity, the source evolved from a Cyg-like Z source, via a Sco-like Z source, to an atoll source. In the Cyg-like interval, the positive correlations are mostly distributed on the HB, which is not consistent with that of the Cyg-like Z source GX 5-1 and Cyg X-2 whose HBs host ambiguous correlations and anti-correlations. From our spectral analyses, it is found that the ratio of the hard emission to the soft emission basically keeps unvaried...

  2. Discovery and identification of infrared counterpart candidates of four Galactic centre low mass X-ray binaries

    CERN Document Server

    Curran, P A; Heras, J A Zurita

    2011-01-01

    The near infrared (nIR)/optical counterparts of low mass X-ray binaries (LMXBs) are often observationally dim and reside in high source density fields which make their identification problematic; however, without such a counterpart identification we are unable to investigate many of the properties of LMXB systems. Here, in the context of a larger identification campaign, we examine the fields of four LMXB systems near the Galactic centre, in a bid to identify nIR/optical counterparts to the previously detected X-ray point sources. We obtain nIR/optical images of the fields with the ESO - New Technology Telescope and apply standard photometric and astrometric calibrations; these data are supplemented by Spitzer-GLIMPSE catalog data. On the basis of positional coincidence with the arcsecond accurate X-ray positions, we identify unambiguous counterpart candidates for XTE J1637-498, IGR J17379-3747, IGR J17585-3057 and GX 9+1. We propose tentative nIR counterparts of four LMXBs which require further investigation...

  3. 76 FR 4896 - Call for Candidates

    Science.gov (United States)

    2011-01-27

    ... From the Federal Register Online via the Government Publishing Office FEDERAL ACCOUNTING STANDARDS ADVISORY BOARD Call for Candidates AGENCY: Federal Accounting Standards Advisory Board. ACTION: Notice... Federal Accounting Standards Advisory Board (FASAB) is currently seeking candidates (candidates must...

  4. Characterization of CdTe substrates and MOCVD Cd 1- xZn xTe epilayers by Raman, photoluminescence and X-ray diffraction techniques

    Science.gov (United States)

    Levy, M.; Amir, N.; Khanin, E.; Muranevich, A.; Nemirovsky, Y.; Beserman, R.

    1998-05-01

    CdTe substrates and the quality of the Cd 1- xZn xTe ( x⩽0.1) epilayers grown by metalorganic chemical vapor deposition (MOCVD) on CdTe substrates, are characterized by Raman scattering and photoluminescence (PL) as well as by X-ray double-crystal rocking curve (DCRC). At a low temperature the intensity of LO phonon is enhanced wherever there is a structural defect. The defect-induced enhancement is due to a large momentum transfer which enhances the intraband Frolich interaction. In addition, the bound exciton peak intensity measured by PL decreases wherever the LO phonon scattering efficiency increases confirming that the defect is the origin of the above Raman enhancement. The quantitative measure of the structural perfection is related to the ratio between the defect band and excitonic peaks in the PL spectra, and correlates with the X-ray full-width at half-maximum (FWHM) of the layer peak. It is shown that in addition to these parameters, the FWHM of the PL defect band is a useful parameter to determine the quality of the epilayer, and a good correlation is obtained between the different parameters. The effect of growth parameters such as zinc partial pressure in the reactor during growth and the reactor design are studied. The results indicate that crystalline imperfection is caused by lattice mismatch between the CdTe substrate and the CdZnTe epilayer and by the nonuniformity of the zinc composition throughout the layers. The quality of the layers is independent of the reactor volume.

  5. Empathy Development in Teacher Candidates

    Science.gov (United States)

    Boyer, Wanda

    2010-01-01

    Using a grounded theory research design, the author examined 180 reflective essays of teacher candidates who participated in a "Learning Process Project," in which they were asked to synthesize and document their discoveries about the learning process over the course of a completely new learning experience as naive learners. This study explored…

  6. Candidate gene prioritization with Endeavour.

    Science.gov (United States)

    Tranchevent, Léon-Charles; Ardeshirdavani, Amin; ElShal, Sarah; Alcaide, Daniel; Aerts, Jan; Auboeuf, Didier; Moreau, Yves

    2016-07-01

    Genomic studies and high-throughput experiments often produce large lists of candidate genes among which only a small fraction are truly relevant to the disease, phenotype or biological process of interest. Gene prioritization tackles this problem by ranking candidate genes by profiling candidates across multiple genomic data sources and integrating this heterogeneous information into a global ranking. We describe an extended version of our gene prioritization method, Endeavour, now available for six species and integrating 75 data sources. The performance (Area Under the Curve) of Endeavour on cross-validation benchmarks using 'gold standard' gene sets varies from 88% (for human phenotypes) to 95% (for worm gene function). In addition, we have also validated our approach using a time-stamped benchmark derived from the Human Phenotype Ontology, which provides a setting close to prospective validation. With this benchmark, using 3854 novel gene-phenotype associations, we observe a performance of 82%. Altogether, our results indicate that this extended version of Endeavour efficiently prioritizes candidate genes. The Endeavour web server is freely available at https://endeavour.esat.kuleuven.be/. PMID:27131783

  7. Candidate Prediction Models and Methods

    DEFF Research Database (Denmark)

    Nielsen, Henrik Aalborg; Nielsen, Torben Skov; Madsen, Henrik;

    2005-01-01

    This document lists candidate prediction models for Work Package 3 (WP3) of the PSO-project called ``Intelligent wind power prediction systems'' (FU4101). The main focus is on the models transforming numerical weather predictions into predictions of power production. The document also outlines the...

  8. Candidate cave entrances on Mars

    Science.gov (United States)

    Cushing, Glen E.

    2012-01-01

    This paper presents newly discovered candidate cave entrances into Martian near-surface lava tubes, volcano-tectonic fracture systems, and pit craters and describes their characteristics and exploration possibilities. These candidates are all collapse features that occur either intermittently along laterally continuous trench-like depressions or in the floors of sheer-walled atypical pit craters. As viewed from orbit, locations of most candidates are visibly consistent with known terrestrial features such as tube-fed lava flows, volcano-tectonic fractures, and pit craters, each of which forms by mechanisms that can produce caves. Although we cannot determine subsurface extents of the Martian features discussed here, some may continue unimpeded for many kilometers if terrestrial examples are indeed analogous. The features presented here were identified in images acquired by the Mars Odyssey's Thermal Emission Imaging System visible-wavelength camera, and by the Mars Reconnaissance Orbiter's Context Camera. Select candidates have since been targeted by the High-Resolution Imaging Science Experiment. Martian caves are promising potential sites for future human habitation and astrobiology investigations; understanding their characteristics is critical for long-term mission planning and for developing the necessary exploration technologies.

  9. Metal Nitrides Grown from Ca/Li Flux: Ca6Te3N2 and New Nitridoferrate(I) Ca6(LixFe1-x)Te2N3.

    Science.gov (United States)

    Dickman, Matthew J; Latturner, Susan E

    2016-08-24

    Two new tellurium-containing nitrides were grown from reactions in molten calcium and lithium. The compound Ca6Te3N2 crystallizes in space group R3̅c (a = 12.000(3)Å, c = 13.147(4)Å; Z = 6); its structure is an anti-type of rinneite (K3NaFeCl6) and 2H perovskite related oxides such as Sr3Co2O6. The compound Ca6(LixFe1-x)Te2N3 where x ≈ 0.48 forms in space group P42/m (a = 8.718(3)Å, c = 6.719(2)Å; Z = 2) with a new stuffed anti-type variant of the Tl3BiCl6 structure. Band structure calculations and easily observable red/green dichroic behavior indicate that Ca6Te3N2 is a highly anisotropic direct band gap semiconductor (Eg = 2.5 eV). Ca6(LixFe1-x)Te2N3 features isolated linear N-Fe-N units with iron in the rare Fe(1+) state. The magnetic behavior of the iron site was characterized by magnetic susceptibility measurements, which indicate a very high magnetic moment (5.16μB) likely due to a high degree of spin-orbit coupling. Inherent disorder at the Fe/Li mixed site frustrates long-range communication between magnetic centers. PMID:27479366

  10. IAEA Director General candidates announced

    International Nuclear Information System (INIS)

    Full text: The IAEA today confirms receipt of the nomination of five candidates for Director General of the IAEA. Nominations of the following individuals have been received by the Chairperson of the IAEA Board of Governors, Ms. Taous Feroukhi: Mr. Jean-Pol Poncelet of Belgium; Mr. Yukiya Amano of Japan; Mr. Ernest Petric of Slovenia; Mr. Abdul Samad Minty of South Africa; and Mr. Luis Echavarri of Spain. The five candidates were nominated in line with a process approved by the Board in October 2008. IAEA Director General Mohamed ElBaradei's term of office expires on 30 November 2009. He has served as Director General since 1997 and has stated that he is not available for a fourth term of office. (IAEA)

  11. Enthalpy screen of drug candidates.

    Science.gov (United States)

    Schön, Arne; Freire, Ernesto

    2016-11-15

    The enthalpic and entropic contributions to the binding affinity of drug candidates have been acknowledged to be important determinants of the quality of a drug molecule. These quantities, usually summarized in the thermodynamic signature, provide a rapid assessment of the forces that drive the binding of a ligand. Having access to the thermodynamic signature in the early stages of the drug discovery process will provide critical information towards the selection of the best drug candidates for development. In this paper, the Enthalpy Screen technique is presented. The enthalpy screen allows fast and accurate determination of the binding enthalpy for hundreds of ligands. As such, it appears to be ideally suited to aid in the ranking of the hundreds of hits that are usually identified after standard high throughput screening.

  12. Leishmaniasis: vaccine candidates and perspectives.

    Science.gov (United States)

    Singh, Bhawana; Sundar, Shyam

    2012-06-01

    Leishmania is a protozoan parasite and a causative agent of the various clinical forms of leishmaniasis. High cost, resistance and toxic side effects of traditional drugs entail identification and development of therapeutic alternatives. The sound understanding of parasite biology is key for identifying novel drug targets, that can induce the cell mediated immunity (mainly CD4+ and CD8+ IFN-gamma mediated responses) polarized towards a Th1 response. These aspects are important in designing a new vaccine along with the consideration of the candidates with respect to their ability to raise memory response in order to improve the vaccine performance. This review is an effort to identify molecules according to their homology with the host and their ability to be used as potent vaccine candidates.

  13. 11 CFR 100.154 - Candidate debates.

    Science.gov (United States)

    2010-01-01

    ... Expenditures § 100.154 Candidate debates. Funds used to defray costs incurred in staging candidate debates in accordance with the provisions of 11 CFR 110.13 and 114.4(f) are not expenditures. ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Candidate debates. 100.154 Section...

  14. 11 CFR 100.92 - Candidate debates.

    Science.gov (United States)

    2010-01-01

    ... Contributions § 100.92 Candidate debates. Funds provided to defray costs incurred in staging candidate debates in accordance with the provisions of 11 CFR 110.13 and 114.4(f) are not contributions. ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Candidate debates. 100.92 Section...

  15. Candidate worldviews for design theory

    DEFF Research Database (Denmark)

    Galle, Per

    2008-01-01

    Our growing body of design theory risks being infected by more inconsistency than is justifiable by genuine disagreement among design theorists. Taking my cue from C. S. Peirce, who argued that theory inevitably rests on basic metaphysical assumptions that theorists ought to be critically aware of......, I demonstrate how ‘insidious inconsistency’ may infect design theory if we ignore his admonition. As a possible remedy, I propose a method by which the philosophy of design may develop sound metaphysical foundations (‘worldviews’) for design theory – and generate philosophical insights into design...... at the same time. Examples are given of how the first steps of the method may be carried out and a number of candidate worldviews are outlined and briefly discussed. In its own way, each worldview answers certain fundamental questions about the nature of design. These include the ontological question of what...

  16. Cardiac evaluation of liver transplant candidates

    OpenAIRE

    Mandell, Mercedes Susan; Lindenfeld, JoAnn; Tsou, Mei-Yung; Zimmerman, Michael

    2008-01-01

    Physicians previously thought that heart disease was rare in patients with end stage liver disease. However, recent evidence shows that the prevalence of ischemic heart disease and cardiomyopathy is increased in transplant candidates compared to most other surgical candidates. Investigators estimate that up to 26% of all liver transplant candidates have at least one critical coronary artery stenosis and that at least half of these patients will die perioperatively of cardiac complications. Ca...

  17. Newly identified YSO candidates towards LDN 1188

    Science.gov (United States)

    Marton , G.; Verebélyi, E.; Kiss, Cs.; Smidla, J.

    2013-11-01

    We present an analysis of young stellar object (YSO) candidates towards the LDN 1188 molecular cloud. The YSO candidates were selected from the WISE all-sky catalogue, based on a statistical method. We found 601 candidates in the region, and classified them as Class I, Flat, and Class II YSOs. Groups were identified and described with the Minimal Spanning Tree (MST) method. Previously identified molecular cores show evidence of ongoing star formation at different stages throughout the cloud complex.

  18. Undercover Stars Among Exoplanet Candidates

    Science.gov (United States)

    2005-03-01

    events by monitoring the brightness of a very large number of stars over extended time intervals. During the past years, it has also included a search for periodic, very shallow "dips" in the brightness of stars, caused by the regular transit of small orbiting objects (small stars, brown dwarfs [2] or Jupiter-size planets). The OGLE team has since announced 177 "planetary transit candidates" from their survey of several hundred thousand stars in three southern sky fields, one in the direction of the Galactic Centre, another within the Carina constellation and the third within the Centaurus/Musca constellations. The nature of the transiting object can however only be established by subsequent radial-velocity observations of the parent star. The size of the velocity variations (the amplitude) is directly related to the mass of the companion object and therefore allows discrimination between stars and planets as the cause of the observed brightness "dip". A Bonanza of Low-Mass Stars An international team of astronomers [3] has made use of the 8.2-m VLT Kueyen telescope for this work. Profiting from the multiplex capacity of the FLAMES/UVES facility that permits to obtain high-resolution spectra of up to 8 objects simultaneously, they have looked at 60 OGLE transit candidate stars, measuring their radial velocities with an accuracy of about 50 m/s [4]. This ambitious programme has so far resulted in the discovery of five new transiting exoplanets (see, e.g., ESO PR 11/04 for the announcement of two of those). Most of the other transit candidates identified by OGLE have turned out to be eclipsing binaries, that is, in most cases common, small and low-mass stars passing in front of a solar-like star. This additional wealth of data on small and light stars is a real bonanza for the astronomers. Constraining the Relation Between Mass and Radius Low-mass stars are exceptionally interesting objects, also because the physical conditions in their interiors have much in common with

  19. Special Education Teacher Candidate Assessment: A Review

    Science.gov (United States)

    McCall, Zach; McHatton, Patricia Alvarez; Shealey, Monika Williams

    2014-01-01

    Teacher preparation has been under intense scrutiny in recent years. In order for preparation of special education teacher candidates to remain viable, candidate assessment practices must apply practices identified in the extant literature base, while special education teacher education researchers must extend this base with rigorous efforts to…

  20. 11 CFR 110.13 - Candidate debates.

    Science.gov (United States)

    2010-01-01

    ... political parties may stage candidate debates in accordance with this section and 11 CFR 114.4(f). (2... also cover or carry candidate debates in accordance with 11 CFR part 100, subparts B and C and part 100... CFR 114.4(f), provided that they are not owned or controlled by a political party, political...

  1. The phase lags of high-frequency quasi-periodic oscillations in four black hole candidates

    NARCIS (Netherlands)

    Méndez, Mariano; Altamirano, Diego; Belloni, Tomaso; Sanna, Andrea

    2013-01-01

    We measured the phase-lag spectrum of the high-frequency quasi-periodic oscillations (QPO) in the black hole systems (at QPO frequencies) GRS 1915+105 (35 Hz and 67 Hz), GRO J1655-40 (300 Hz and 450 Hz), XTE J1550-564 (180 Hz and 280 Hz) and IGR J17091-3624 (67 Hz). The lag spectra of the 67-Hz QPO

  2. Bioinformatics methods for identifying candidate disease genes

    NARCIS (Netherlands)

    Driel, M.A. van; Brunner, H.G.

    2006-01-01

    With the explosion in genomic and functional genomics information, methods for disease gene identification are rapidly evolving. Databases are now essential to the process of selecting candidate disease genes. Combining positional information with disease characteristics and functional information i

  3. Cattle Candidate Genes for Milk Production Traits

    OpenAIRE

    Kadlec, Tomáš

    2012-01-01

    The aim of this thesis is to make an overview of important candidate genes affecting milk yield and milk quality parameters, with an emphasis on genes associated with the quantity and quality of milk proteins and milk fat.

  4. Evaluating historical candidate genes for schizophrenia

    DEFF Research Database (Denmark)

    Farrell, M S; Werge, T; Sklar, P;

    2015-01-01

    Prior to the genome-wide association era, candidate gene studies were a major approach in schizophrenia genetics. In this invited review, we consider the current status of 25 historical candidate genes for schizophrenia (for example, COMT, DISC1, DTNBP1 and NRG1). The initial study for 24...... of these genes explicitly evaluated common variant hypotheses about schizophrenia. Our evaluation included a meta-analysis of the candidate gene literature, incorporation of the results of the largest genomic study yet published for schizophrenia, ratings from informed researchers who have published...... on these genes, and ratings from 24 schizophrenia geneticists. On the basis of current empirical evidence and mostly consensual assessments of informed opinion, it appears that the historical candidate gene literature did not yield clear insights into the genetic basis of schizophrenia. A likely reason why...

  5. Towards Treating Chemistry Teacher Candidates as Human

    Science.gov (United States)

    Lewthwaite, Brian Ellis

    2008-05-01

    This research inquiry investigates the factors influencing chemistry teacher candidates’ development during their extended practica in the second and final year of an After-Degree Bachelor of Education at a university in central Canada. A variety of data sources are used to identify the risk and protective factors impeding and contributing to the achievement of their chemistry pedagogical aspirations. Two theoretical frameworks, both having their origins in the pioneering work of Kurt Lewin, are used to conceptualize how a complex amalgam of personal attribute and environmental factors and the interplay among these factors influence teacher candidate developmental trajectories. The tenets of both Bronfenbrenner’s bioecological model and Learning Environment research provide insights into how the factors influencing teacher candidate development can be understood and systematically documented to provide a template for reflective consideration of the practicum experience for both teacher candidates and those involved in fostering the development of chemistry teacher candidates.

  6. Do People 'Like' Candidates on Facebook?

    DEFF Research Database (Denmark)

    Nielsen, Rasmus Kleis

    The online popularity of a few exceptional candidates has led many to suggest that social media have given politicians powerful ways of communicating directly with voters. In this paper, we examine whether this is happening on a significant scale and show, based on analysis of 224 candidates....... We therefore suggest that the political implications of social media are generally better understood in terms of facilitating indirect communication and institutional change than in terms of direct communication....

  7. Candidal Leukoplakia on Patient with Removable Denture

    OpenAIRE

    Shiril Paskalis; Anandina Irmagita

    2013-01-01

    Candida infection is a common problem in patients using removable dentures, with the most frequent type is denture stomatitis. But other type of candidal infection could also happen in these patients, such as candidal leukoplakia. We reported a 61 years old female patient who complained a painful lesion under her lower removable denture. Oral examination revealed white plaque that could not be rubbed over an ulcer on the lingual part of alveolar processes under the lower removable denture pla...

  8. Cardiac evaluation of liver transplant candidates

    Institute of Scientific and Technical Information of China (English)

    Mercedes Susan Mandell; JoAnn Lindenfeld; Mei-Yung Tsou; Michael Zimmerman

    2008-01-01

    Physicians previously thought that heart disease was rare in patients with end stage liver disease. However, recent evidence shows that the prevalence of ischemic heart disease and cardiomyopathy is increased in transplant candidates compared to most other surgical candidates. Investigators estimate that up to 26% of all liver transplant candidates have at least one critical coronary artery stenosis and that at least half of these patients will die perioperatively of cardiac complications. Cardiomyopathy also occurs in greater frequency. While all patients with advanced cardiac disease have defects in cardiac performance, a larger than expected number of patients have classical findings of dilated, restrictive and hypertropic cardiomyopathy. This may explain why up to 56% of patients suffer from hypoxemia due to pulmonary edema following transplant surgery. There is considerable controversy on how to screen transplant candidates for the presence of heart disease. Questions focus upon, which patients should be screened and what tests should be used. This review examines screening strategies for transplant candidates and details the prognostic value of common tests used to identify ischemic heart disease. We also review the physiological consequences of cardiomyopathy in transplant candidates and explore the specific syndrome of "cirrhotic cardiomyopathy".

  9. Propeller-Effect Interpretation of MAXI/GSC Light Curves of 4U 1608-52 and AqlX-1 and application to XTE J1701-462

    CERN Document Server

    Asai, K; Mihara, T; Sugizaki, M; Serino, M; Nakahira, S; Negoro, H; Ueda, Y; Yamaoka, K

    2013-01-01

    We present the luminosity dwell-time distributions during the hard states of low-mass X-ray binaries containing a neutron star, 4U 1608-52 and AqlX-1, observed with MAXI/GSC. The luminosity distributions show a steep cut-off in the low-luminosity side at $\\sim1.0 \\times 10^{36}$ erg s$^{-1}$ in both the two sources. The cut-off implies a rapid luminosity decrease in their outburst decay phases, and the feature can be interpreted as due the propeller effect. We estimated the surface magnetic field of the neutron star to be (0.5--1.6) $\\times 10^8$ G in 4U 1608-52 and (0.6--1.9) $\\times 10^8$ G in AqlX-1 from the cut-off luminosity. We applied the same propeller mechanism to the similar rapid luminosity decrease observed in the transient Z-source, XTE J1701-462, with RXTE/ASM. Assuming that spin period of the neutron star is in the order of milliseconds, the observed cut-off luminosity deduces surface magnetic field in the order of $10^9$ G.

  10. A PROPELLER-EFFECT INTERPRETATION OF MAXI/GSC LIGHT CURVES OF 4U 1608-52 AND Aql X-1 AND APPLICATION TO XTE J1701-462

    Energy Technology Data Exchange (ETDEWEB)

    Asai, K.; Matsuoka, M.; Mihara, T.; Sugizaki, M.; Serino, M. [MAXI Team, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Nakahira, S. [ISS Science Project Office, ISAS, JAXA, 2-1-1 Sengen, Tsukuba, Ibaraki 305-8505 (Japan); Negoro, H. [Department of Physics, Nihon University, 1-8-14 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8308 (Japan); Ueda, Y. [Department of Astronomy, Kyoto University, Kitashirakawa, Oiwake-cho, Sakyo-ku, Kyoto 606-8502 (Japan); Yamaoka, K., E-mail: kazumi@crab.riken.jp [Institute of Space and Astronautical Science, JAXA, 3-1-1 Yoshino-dai, Chuo-ku, Sagamihara, Kanagawa 252-5210 (Japan)

    2013-08-20

    We present the luminosity dwell-time distributions during the hard states of two low-mass X-ray binaries containing a neutron star (NS), 4U 1608-52 and Aql X-1, observed with MAXI/GSC. The luminosity distributions show a steep cutoff on the low-luminosity side at {approx}1.0 Multiplication-Sign 10{sup 36} erg s{sup -1} in both sources. The cutoff implies a rapid luminosity decrease in their outburst decay phases and this decrease can be interpreted as being due to the propeller effect. We estimate the surface magnetic field of 4U 1608-52 to be (0.5-1.6) Multiplication-Sign 10{sup 8} G and Aql X-1 to be (0.6-1.9) Multiplication-Sign 10{sup 8} G from the cutoff luminosity and apply the same propeller mechanism to the similar rapid luminosity decrease observed in the transient Z source, XTE J1701-462, with RXTE/ASM. Assuming that the spin period of the NS is on the order of milliseconds, the observed cutoff luminosity implies a surface magnetic field on the order of 10{sup 9} G.

  11. Development of a highly efficient conversion electron Moessbauer spectroscopy (CEMS) detector for low temperature (<20 K) measurements and tests on Fe / (Eu{sub x}Pb{sub 1-x})Te bilayers; Desenvolvimento de um detector de alta eficiencia para espectroscopia Moessbauer de eletrons de conversao (CEMS) a baixas temperaturas (<20K) e testes em bicamadas Fe / (Eu{sub x}Pb{sub 1-x})Te

    Energy Technology Data Exchange (ETDEWEB)

    Pombo, Carlos Jose da Silva Matos

    2006-07-01

    The {sup 57}Fe Moessbauer spectroscopy is a nuclear, non-destructive technique used for the investigation of structural, magnetic and hyperfine properties of several materials. It is a powerful tool in characterizing materials in physics, metallurgy, geology and biology field areas, especially magnetic materials, alloys and minerals containing Fe. Lately, the Conversion Electron Moessbauer Spectroscopy (CEMS) is widely used in making studies on ultra-thin magnetic films, as well as other nanostructured materials. In case of magnetic nanostructures, low temperature (LT) studies are especially important due to the possibility of dealing with superparamagnetic effects. In this work it was developed a CEMS measurement system for low temperatures (<20 K) based on a solid-state electron multiplier (Channeltron{sup R}) and an optical cryostat (Model SVT-400, Janis Research Co, USA), from which the project was originally conceived at the Applied Physics / Moessbauer spectroscopy Department from University of Duisburg-Essen, Germany. The LT-CEMS system was fully built, tested and successfully applied in a preliminary characterization of Fe/(Eu{sub x}Pb{sub 1-x})Te(111) bilayers with use of a 15 angstrom, {sup 57} Fe probe layer, with reasonable results at sample temperatures as low as 8 K. (author)

  12. 米其林加快适应中国市场——向中国推出节能、高效卡车/挂车轮胎XZA 2 Energy和XTE 2%Michelin Plan to Introduce New High-tech Tyre Products to China Market

    Institute of Scientific and Technical Information of China (English)

    王作函

    2010-01-01

    @@ 2010年1月20日,米其林在京宣布向中国市场推出2款专门为中国用户定制的节能、高效卡车轮胎--XZA 2 Energy和XTE 2.同时,新上任的米其林卡客车轮胎部高级副总裁夏茂廷还对米其林卡客车轮胎下一步在中国的发展作了介绍.

  13. Cattle Candidate Genes for Meat Production Traits

    OpenAIRE

    Bláhová, Alice

    2013-01-01

    The objective of this study was to compile a summary of the most important candidate genes for meat production. The studied genes were: GH, GHR, MSTN, MyoD family, leptin, IGF, TG5, SCD, DGAT and STAT5A. Growth hormone (GH) is involved in physiological processes of growth and metabolism. Growth hormone receptor (GHR) has been proposed as a candidate gene for meat production in cattle. Myostatin is a significant marker. It affects the amount of muscle, reduces marbling and elevate meat tendern...

  14. Issue-Advocacy versus Candidate Advertising: Effects on Candidate Preferences and Democratic Process.

    Science.gov (United States)

    Pfau, Michael; Holbert, R. Lance; Szabo, Erin Alison; Kaminski, Kelly

    2002-01-01

    Examines the influence of soft-money-sponsored issue-advocacy advertising in U.S. House and Senate campaigns, comparing its effects against candidate-sponsored positive advertising and contrast advertising on viewers' candidate preferences and on their attitude that reflect democratic values. Reveals no main effects for advertising approach on…

  15. Towards Treating Chemistry Teacher Candidates as Human

    Science.gov (United States)

    Lewthwaite, Brian Ellis

    2008-01-01

    This research inquiry investigates the factors influencing chemistry teacher candidates' development during their extended practica in the second and final year of an After-Degree Bachelor of Education at a university in central Canada. A variety of data sources are used to identify the risk and protective factors impeding and contributing to the…

  16. Spectroscopy of Hyades L dwarf candidates

    CERN Document Server

    Lodieu, N; Bejar, V J S

    2014-01-01

    We present the results of photometric, astrometric, and spectroscopic follow-up of L dwarf candidates identified in the Hyades cluster by Hogan et al. (2008). We obtained low-resolution optical spectroscopy with the OSIRIS spectrograph on the Gran Telescopio de Canarias for all 12 L dwarf candidates as well as new J-band imaging for a subsample of eight to confirm their proper motion. We also present mid-infrared photometry from the Wise Field Infrared Survey Explorer (WISE) for the Hyades L and T dwarf candidates and estimate their spectroscopic distances, effective temperatures, and masses. We confirm the cool nature of several L dwarf candidates and confirm astrometrically their membership, bridging the gap between the coolest M dwarfs and the two T dwarfs previously reported in the Hyades cluster. These members represent valuable spectral templates at an age of 625 Myr and slightly super solar metallicity (Fe/H=+0.13). We update the Hyades mass function across the hydrogen-burning limit and in the substel...

  17. 76 FR 36130 - Call for Candidates

    Science.gov (United States)

    2011-06-21

    ... From the Federal Register Online via the Government Publishing Office FEDERAL ACCOUNTING STANDARDS ADVISORY BOARD Call for Candidates AGENCY: Federal Accounting Standards Advisory Board. ACTION: Request for... Accounting Standards Advisory Board (FASAB or the Board) with the requested materials in response to...

  18. 11 CFR 9003.2 - Candidate certifications.

    Science.gov (United States)

    2010-01-01

    ... excess of the aggregate payments to which they will be entitled under 11 CFR part 9004. (2) That no... funds under 11 CFR 9003.2(c)(3) shall not count against such candidate's $50,000 expenditure limitation... expenditures in excess of the limitations of 11 CFR 110.8(a), the Commission may seek civil penalties under...

  19. Emotional Intelligence and Beginning Teacher Candidates

    Science.gov (United States)

    Justice, Madeline; Espinoza, Sue

    2007-01-01

    According to the Bureau of Labor Statistics, Texas will need over 82,000 new teachers by 2008. Many teachers are leaving the profession within 5 years of being employed. Closing a revolving door, teacher preparation programs are discussing this phenomenon. One hundred sixty beginning teacher candidates were surveyed using the Emotional Skills…

  20. Fuzzy Treatment of Candidate Outliers in Measurements

    Directory of Open Access Journals (Sweden)

    Giampaolo E. D'Errico

    2012-01-01

    Full Text Available Robustness against the possible occurrence of outlying observations is critical to the performance of a measurement process. Open questions relevant to statistical testing for candidate outliers are reviewed. A novel fuzzy logic approach is developed and exemplified in a metrology context. A simulation procedure is presented and discussed by comparing fuzzy versus probabilistic models.

  1. Promoting Team Leadership Skills in Doctoral Candidates

    Science.gov (United States)

    Suleiman, Mahmoud; Whetton, Danny

    2014-01-01

    Doctoral programs can serve as an optimal opportunity for candidates to engage in tasks and activities to transform them and their schools. The paradigm shifts in such preparation involve moving from sitting and getting to making and taking. Most importantly, it requires building leadership skills and styles necessary to bring about desired change…

  2. Gallium-67 imaging in candidal esophagitis

    Energy Technology Data Exchange (ETDEWEB)

    Rundback, J.H.; Goldfarb, C.R.; Ongseng, F. (Beth Israel Medical Center, New York, NY (USA))

    1990-01-01

    Ga-67 scanning has been used to evaluate esophageal carcinoma. It has demonstrated candidal infection in other body sites and, in one previous case, in the esophagus. The authors present a case of diffuse esophageal uptake of Ga-67 in esophageal candidiasis.

  3. The Responsibility Education of Teacher Candidates

    Science.gov (United States)

    Toremen, Fatih

    2011-01-01

    In this study, it was aimed to take the views and suggestions of academicians working at the faculty of education on what can be done about teacher candidates' responsibility education. This study was designed on the basis of qualitative research approach and purposive sampling method was used. Data were collected by unstructured interview method…

  4. Candidal Leukoplakia on Patient with Removable Denture

    Directory of Open Access Journals (Sweden)

    Shiril Paskalis

    2013-07-01

    Full Text Available Candida infection is a common problem in patients using removable dentures, with the most frequent type is denture stomatitis. But other type of candidal infection could also happen in these patients, such as candidal leukoplakia. We reported a 61 years old female patient who complained a painful lesion under her lower removable denture. Oral examination revealed white plaque that could not be rubbed over an ulcer on the lingual part of alveolar processes under the lower removable denture plate, and also an erythematous area on palatum durum above the upper full denture. The patient was suspected to have candidal leukoplakia on the lingual part of the mandible and denture stomatitis on the palate area. The treatment consisted of nystatin oral suspension, chlorhexidine solution, multivitamins, along with denture replacement and oral health education. The entire lesion resolved within 2 months therapy. Candidal infection treatment on denture patient needs not only medication or denture replacement, but also patient compliance to achieve maximal result.

  5. FAME's Search for Extrasolar Planet Candidates

    Science.gov (United States)

    Johnston, K.

    FAME is a five year survey mission to observe the positions, proper motions, and parallaxes of 40,000,000 stars down to 15th magnitude with accuracies of 50 microarcseconds at 9th magnitude. In addition to producing an astrometric and photometric catalog unparalleled for its accuracy and size, the survey will provide significant astrophysics results and search for extrasolar planet candidates.

  6. Secondary Teacher Candidates' Lesson Planning Learning

    Science.gov (United States)

    Santoyo, Christina; Zhang, Shaoan

    2016-01-01

    Teacher candidates (TCs) use clinical experiences to enact concepts taught in their university courses; therefore field experiences may be the most important component of teacher preparation (Hammerness et al., 2005). TCs require support and guidance as they learn to adapt curriculum materials for effective use in the classroom (Davis, 2006). They…

  7. Candidate genes in ocular dominance plasticity

    NARCIS (Netherlands)

    M.L. Rietman; J.-P. Sommeijer; C.N. Levelt; J.A. Heimel; A.B. Brussaard; J.G.G. Borst; Y. Elgersma; N. Galjart; G.T. van der Horst; C.M. Pennartz; A.B. Smit; B.M. Spruijt; M. Verhage; C.I. de Zeeuw

    2012-01-01

    Many studies have been devoted to the identification of genes involved in experience-dependent plasticity in the visual cortex. To discover new candidate genes, we have reexamined data from one such study on ocular dominance (OD) plasticity in recombinant inbred BXD mouse strains. We have correlated

  8. Microlensing Binaries with Candidate Brown Dwarf Companions

    DEFF Research Database (Denmark)

    Shin, I.-G; Han, C.; Gould, A.;

    2012-01-01

    Brown dwarfs are important objects because they may provide a missing link between stars and planets, two populations that have dramatically different formation histories. In this paper, we present the candidate binaries with brown dwarf companions that are found by analyzing binary microlensing ...

  9. Gallium-67 imaging in candidal esophagitis

    International Nuclear Information System (INIS)

    Ga-67 scanning has been used to evaluate esophageal carcinoma. It has demonstrated candidal infection in other body sites and, in one previous case, in the esophagus. The authors present a case of diffuse esophageal uptake of Ga-67 in esophageal candidiasis

  10. Social Justice Perceptions of Teacher Candidates

    Science.gov (United States)

    Turhan, Muhammed

    2010-01-01

    This study aims to determine the social justice perceptions of teacher candidates being trained in an education faculty. For this purpose, national and international literature was reviewed by the researcher and a 32-item questionnaire was developed and implemented on 237 senior year education faculty students. Data from the questionnaires were…

  11. Candidate genes in ocular dominance plasticity

    Directory of Open Access Journals (Sweden)

    M. Liset Rietman

    2012-02-01

    Full Text Available The objective of this study was to identify new candidate genes involved in experience-dependent plasticity. To this aim, we combined previously obtained data from recombinant inbred BXD strains on ocular dominance (OD plasticity and gene expression levels in the neocortex. We validated our approach using a list of genes which alter OD plasticity when inactivated. The expression levels of one fifth of these genes correlated with the amount of OD plasticity. Moreover, the two genes with the highest relative inter-strain differences were among the correlated genes. This suggests that correlation between gene expression levels and OD plasticity is indeed likely to point to genes with a causal role in modulating or generating plasticity in the visual cortex. After this validation on known plasticity genes, we identified new candidate genes by a multi-step approach. First, a list was compiled of all genes of which the expression level in BXD strains correlate with the amount of OD plasticity. To narrow this list to the more promising candidates, we took its cross-section with a list of genes co-regulated with the sensitive period for OD plasticity and a list of genes associated with pathways implicated in OD plasticity. This analysis resulted in a list of 32 candidate genes. The list contained unproven, but not surprising, candidates, such as the genes for IGF-1, NCAM1, NOGO-A, the gamma2 subunit of the GABA(A receptor, acetylcholine esterase and the catalytic subunit of cAMP-dependent protein kinase A. This was indicative of the viability of our approach, but more interesting were the novel candidate genes: Akap7, Akt1, Camk2d, Cckbr, Cd44, Crim1, Ctdsp2, Dnajc5, Gnai1, Itpka, Mapk8, Nbea, Nfatc3, Nlk, Npy5r, Phf21a, Phip, Ppm1l, Ppp1r1b, Rbbp4, Slc1a3, Slit2, Socs2, Spock3, St8sia1, Zfp207. The possible role of some of these candidates is discussed in the article.

  12. 22 CFR 11.8 - Travel expenses of candidates.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Travel expenses of candidates. 11.8 Section 11... Travel expenses of candidates. The travel and other personal expenses of candidates incurred in... Department may issue round-trip invitational travel orders to bring candidates to Washington at...

  13. 32 CFR 901.6 - Candidate fitness test requirement.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Candidate fitness test requirement. 901.6... Requirements § 901.6 Candidate fitness test requirement. Before being offered an appointment, candidates must take a Candidate Fitness Test (CFT) which consists of exercises designed to measure muscular...

  14. Candidate marketing takes the guessing game out of choosing employers.

    Science.gov (United States)

    Russell, Judith; Havel, Stacey

    2010-01-01

    Candidate marketing builds a foundation for relationships between employers and potential employees. Additionally, candidate marketing differentiates organizations in the marketplace. Organizations using candidate marketing to communicate the employer brand can expect a higher quality of candidates, and new employees are better prepared for the work environment and culture. Today, organizations can use a variety of integrated tools and techniques to communicate and build relationships with candidates. Candidate marketing demonstrates an organization's willingness towards transparency, and ability to invite open conversations between candidates and members of the organizations.

  15. Candidate marketing takes the guessing game out of choosing employers.

    Science.gov (United States)

    Russell, Judith; Havel, Stacey

    2010-01-01

    Candidate marketing builds a foundation for relationships between employers and potential employees. Additionally, candidate marketing differentiates organizations in the marketplace. Organizations using candidate marketing to communicate the employer brand can expect a higher quality of candidates, and new employees are better prepared for the work environment and culture. Today, organizations can use a variety of integrated tools and techniques to communicate and build relationships with candidates. Candidate marketing demonstrates an organization's willingness towards transparency, and ability to invite open conversations between candidates and members of the organizations. PMID:20672542

  16. Attitudes of Teacher Candidates Towards Teaching Profession

    Directory of Open Access Journals (Sweden)

    Aykut Emre BOZDOĞAN

    2007-12-01

    Full Text Available The objective of this study is to determine the attitudes of teacher candidates regarding teaching profession from the point of view of different variables. This study was taken place at Ahi Ervan University Teachers’ College in 2006-2007 year of education and 181 Applied science and Social science students participated it. In order to obtain the data of the research scanning method entitled “Determination of Attitude Towards Teaching Profession” was used which was developed by Aşkar and Erden (1987 . During the analysis of the research data SPSS 12.0 program and the necessary statistical methods were used to analize the data of the research. As a result of the research it is understood that the attitudes of teacher candidates change according to sex and factor that made them to choose the department they study.

  17. Spectroscopic follow up of Kepler planet candidates

    DEFF Research Database (Denmark)

    Latham..[], D. W.; Cochran, W. D.; Marcy, G.W.;

    2010-01-01

    Spectroscopic follow-up observations play a crucial role in the confirmation and characterization of transiting planet candidates identified by Kepler. The most challenging part of this work is the determination of radial velocities with a precision approaching 1 m/s in order to derive masses from...... spectroscopic orbits. The most precious resource for this work is HIRES on Keck I, to be joined by HARPS-North on the William Herschel Telescope when that new spectrometer comes on line in two years. Because a large fraction of the planet candidates are in fact stellar systems involving eclipsing stars...... and not planets, our strategy is to start with reconnaissance spectroscopy using smaller telescopes, to sort out and reject as many of the false positives as possible before going to Keck. During the first Kepler observing season in 2009, more than 100 nights of telescope time were allocated for this work, using...

  18. Candidate Species Selection: Cultural and Photosynthetic Aspects

    Science.gov (United States)

    Mitchell, C. A.

    1982-01-01

    Cultural information is provided for a data base that will be used to select candidate crop species for a controlled ecological life support system (CELSS). Lists of food crops which will satisfy most nutritional requirements of humans and also fit within the scope of cultural restrictions that logically would apply to a closed, regenerating system were generated. Cultural and environmental conditions that will allow the most rapid production of edible biomass from candidate species in the shortest possible time are identified. Cultivars which are most productive in terms of edible biomass production by (CE) conditions, and which respond to the ever-closed approach to optimization realized by each shortened production cycle are selected. The experimental approach with lettuce was to grow the crop hydroponically in a growth chamber and to manipulate such variables as light level and duration, day/night temperature, and nutrient form and level in the solution culture.

  19. New drug candidates in tuberculosis treatment

    Directory of Open Access Journals (Sweden)

    Begüm Evranos Aksöz

    2014-12-01

    makes them quit the treatment. From these problems emerges the need for development of effective new drugs, with smaller duration of therapy, less side effects and without the problem of resistance. After a long period such as 40 years, a new drug molecule bedaquiline was approved in December 2012 by FDA while the drug was in phase II research. Bedaquiline will be used in multidrug resistant tuberculosis therapy. When the chemical structures of bedaquilline and other candidate drugs were examined, the structures such as diarylquinoline, oxazolidinone, nitroimidazole, ethylenediamine drew attention. These common structures will be directive in designing new molecules. In this review, bedaquiline and other candidate drug molecules such as sutezolide, linezolide, PA-824, delamanide, rifapentine, gatifloxacin, moxifloxacin, BTZ-043, TBA-354, CPZEN-45, DC-159a, Q201, SQ-609, SQ-641 were mentioned.

  20. Reducing stigma and discrimination: Candidate interventions

    OpenAIRE

    Kassam Aliya; Brohan Elaine; Thornicroft Graham; Lewis-Holmes Elanor

    2008-01-01

    Abstract This paper proposes that stigma in relation to people with mental illness can be understood as a combination of problems of knowledge (ignorance), attitudes (prejudice) and behaviour (discrimination). From a literature review, a series of candidate interventions are identified which may be effective in reducing stigmatisation and discrimination at the following levels: individuals with mental illness and their family members; the workplace; and local, national and international. The ...

  1. Tantalum oxide coatings as candidate environmental barriers

    OpenAIRE

    Moldovan, Monica; Weyant, C. M.; Johnson, D. Lynn; Faber, K. T.

    2004-01-01

    Tantalum (Ta) oxide, due to its high-temperature capabilities and thermal expansion coefficient similar to silicon nitride, is a promising candidate for environmental barriers for silicon (Si) nitride-based ceramics. This paper focuses on the development of plasma-sprayed Ta oxide as an environmental barrier coating for silicon nitride. Using a D-optimal design of experiments, plasma-spray processing variables were optimized to maximize coating density. The effect of processing variables on c...

  2. Critical Thinking Tendencies of Music Teacher Candidates

    OpenAIRE

    Duygu PİJİ KÜÇÜK; Yusuf Barış UZUN

    2013-01-01

    In this study, determining critical thinking and education levels, which are in sub-dimensions, of music teacher candidates, determining critical thinking tendency and the relations between sub dimensions and detecting if or if not critical thinking tendency creates a difference in terms of gender, class and what type of school they graduated from are aimed. Work group composes of 274 students being educated in the Departments of Music Education GSEB of Education Faculty of Bolu Abant İzzet B...

  3. Various Approaches for Targeting Quasar Candidates

    Science.gov (United States)

    Zhang, Y.; Zhao, Y.

    2015-09-01

    With the establishment and development of space-based and ground-based observational facilities, the improvement of scientific output of high-cost facilities is still a hot issue for astronomers. The discovery of new and rare quasars attracts much attention. Different methods to select quasar candidates are in bloom. Among them, some are based on color cuts, some are from multiwavelength data, some rely on variability of quasars, some are based on data mining, and some depend on ensemble methods.

  4. MANAGEMENT OF ALLOSENSITIZED CARDIAC TRANSPLANT CANDIDATES

    OpenAIRE

    Velez, Mauricio; Johnson, Maryl R.

    2009-01-01

    Cardiac transplantation remains the best treatment in advanced heart failure patients with a high risk of death. However, an inadequate supply of donor hearts decreases the likelihood of transplantation for many patients. Ventricular assist devices (VAD) are being increasingly used as a bridge to transplant in patients who may not survive long enough to receive a heart. This expansion in VAD use has been associated with increasing rates of allosensitization in cardiac transplant candidates. A...

  5. Optical durability testing of candidate solar mirrors

    Energy Technology Data Exchange (ETDEWEB)

    Jorgensen, G.; Kennedy, C.; King, D.; Terwilliger, K.

    2000-03-24

    Durability testing of a variety of candidate solar reflector materials at outdoor test sites and in laboratory accelerated weathering chambers is the main activity within the Advanced Materials task of the Concentrated Solar Power (CSP) Program. Outdoor exposure testing (OET) at up to eight outdoor, worldwide exposure sites has been underway for several years. This includes collaboration under the auspices of the International Energy Agency (IEA) Solar Power and Chemical Energy Systems (SolarPACES) agreement. Outdoor sites are fully instrumented in terms of monitoring meteorological conditions and solar irradiance. Candidate materials are optically characterized prior to being subjected to exposure in real and simulated weathering environments. Optical durability is quantified by periodically re-measuring hemispherical and specular reflectance as a function of exposure time. By closely monitoring the site- and time-dependent environmental stress conditions experienced by the material samples, site-dependent loss of performance may be quantified. In addition, accelerated exposure testing (AET) of these materials in parallel under laboratory-controlled conditions may permit correlating the outdoor results with AET, and subsequently predicting service lifetimes. Test results to date for a large number of candidate solar reflector materials are presented in this report. Acronyms are defined. Based upon OET and AET results to date, conclusions can be drawn about the optical durability of the candidate reflector materials. The optical durability of thin glass, thick glass, and two metallized polymers can be characterized as excellent. The all-polymeric construction, several of the aluminized reflectors, and a metallized polymer can be characterized as having intermediate durability and require further improvement, testing and evaluation, or both.

  6. Comparing Candidate Selection : A Feminist Institutionalist Approach

    OpenAIRE

    Bjarnegard, Elin; Kenny, Meryl

    2016-01-01

    This contribution evaluates the theoretical and methodological challenges ofresearching the gendered dynamics of candidate selection in comparativeperspective. It argues that comparative studies should take into account not only thegendered nature of political parties and their wider institutional context, but mustalso investigate the informal aspects of the selection process and their genderedconsequences. The article explores these dynamics by revisiting original in-depthresearch on the can...

  7. Nonclinical Development of BCG Replacement Vaccine Candidates

    OpenAIRE

    Bernd Eisele; Martin Gengenbacher; Reginald Kidd; David McCown; Sheldon Morris; Steven Derrick; David Hokey; Dominick Laddy; Rosemary Chang; Megan Fitzpatrick; Leander Grode; Kamalakannan Velmurugan; Stefan H. E. Kaufmann; John Fulkerson; Brennan, Michael J.

    2013-01-01

    The failure of current Mycobacterium bovis bacille Calmette–Guérin (BCG) vaccines, given to neonates to protect against adult tuberculosis and the risk of using these live vaccines in HIV-infected infants, has emphasized the need for generating new, more efficacious and safer replacement vaccines. With the availability of genetic techniques for constructing recombinant BCG (rBCG) strains containing well-defined gene deletions or insertions, new vaccine candidates are under evaluation at both ...

  8. Alcoholism and Alternative Splicing of Candidate Genes

    OpenAIRE

    Toshikazu Sasabe; Shoichi Ishiura

    2010-01-01

    Gene expression studies have shown that expression patterns of several genes have changed during the development of alcoholism. Gene expression is regulated not only at the level of transcription but also through alternative splicing of pre-mRNA. In this review, we discuss some of the evidence suggesting that alternative splicing of candidate genes such as DRD2 (encoding dopamine D2 receptor) may form the basis of the mechanisms underlying the pathophysiology of alcoholism. These reports sugg...

  9. Nuclear safety in EU candidate countries

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-10-01

    Nuclear safety in the candidate countries to the European Union is a major issue that needs to be addressed in the framework of the enlargement process. Therefore WENRA members considered it was their duty to offer their technical assistance to their Governments and the European Union Institutions. They decided to express their collective opinion on nuclear safety in those candidate countries having at least one nuclear power plant: Bulgaria, the Czech Republic, Hungary, Lithuania, Romania, Slovakia and Slovenia. The report is structured as follows: A foreword including background information, structure of the report and the methodology used, General conclusions of WENRA members reflecting their collective opinion, For each candidate country, an executive summary, a chapter on the status of the regulatory regime and regulatory body, and a chapter on the nuclear power plant safety status. Two annexes are added to address the generic safety characteristics and safety issues for RBMK and VVER plants. The report does not cover radiation protection and decommissioning issues, while safety aspects of spent fuel and radioactive waste management are only covered as regards on-site provisions. In order to produce this report, WENRA used different means: For the chapters on the regulatory regimes and regulatory bodies, experts from WENRA did the work. For the chapters on nuclear power plant safety status, experts from WENRA and from French and German technical support organisations did the work. Taking into account the contents of these chapters, WENRA has formulated its general conclusions in this report.

  10. Searching for candidate genes for male infertility

    Institute of Scientific and Technical Information of China (English)

    B.N.Truong; E.K.Moses; J.E.Armes; D.J.Venter; H.W.G.Baker

    2003-01-01

    Aim: We describe an approach to search for candidate genes for male infertility using the two human genome databases: the public University of California at Santa Cruz (UCSC) and private Celera databases which list known and predicted gene sequences and provide related information such as gene function, tissue expression,known mutations and single nucleotide polymorphisms (SNPs). Methods and Results: To demonstrate this in silico research, the following male infertility candidate genes were selected: (1) human BOULE, mutations of which may lead to germ cell arrest at the primary spermatocyte stage, (2) mutations of casein kinase 2 alpha genes which may cause globozoospermia, (3) DMR-N9 which is possibly involved in the spermatogenic defect of myotonic dystrophy and (4) several testes expressed genes at or near the breakpoints of a balanced translocation associated with hypospermatogenesis. We indicate how information derived from the human genome databases can be used to confirm these candidate genes may be pathogenic by studying RNA expression in tissue arrays using in situ hybridization and gene sequencing. Conclusion: The paper explains the new approach to discovering genetic causes of male infertility using information about the human genome. ( Asian J Andro1 2003 Jun; 5:137-147 )

  11. UNCOVERING THE NUCLEUS CANDIDATE FOR NGC 253

    Energy Technology Data Exchange (ETDEWEB)

    Günthardt, G. I.; Camperi, J. A. [Observatorio Astronómico, Universidad Nacional de Córdoba (Argentina); Agüero, M. P. [Observatorio Astronómico, Universidad Nacional de Córdoba, and CONICET (Argentina); Díaz, R. J.; Gomez, P. L.; Schirmer, M. [Gemini Observatory, AURA (United States); Bosch, G., E-mail: gunth@oac.uncor.edu, E-mail: camperi@oac.uncor.edu, E-mail: mpaguero@oac.uncor.edu, E-mail: rdiaz@gemini.edu, E-mail: pgomez@gemini.edu, E-mail: mschirmer@gemini.edu, E-mail: guille@fcaglp.unlp.edu.ar [Instituto de Astrofísica de La Plata (CONICET-UNLP) (Argentina)

    2015-11-15

    NGC 253 is the nearest spiral galaxy with a nuclear starburst that becomes the best candidate for studying the relationship between starburst and active galactic nucleus activity. However, this central region is veiled by large amounts of dust, and it has been so far unclear which is the true dynamical nucleus to the point that there is no strong evidence that the galaxy harbors a supermassive black hole co-evolving with the starburst as was supposed earlier. Near-infrared (NIR) spectroscopy, especially NIR emission line analysis, could be advantageous in shedding light on the true nucleus identity. Using Flamingos-2 at Gemini South we have taken deep K-band spectra along the major axis of the central structure and through the brightest infrared source. In this work, we present evidence showing that the brightest NIR and mid-infrared source in the central region, already known as radio source TH7 and so far considered just a large stellar supercluster, in fact presents various symptoms of a genuine galactic nucleus. Therefore, it should be considered a valid nucleus candidate. Mentioning some distinctive aspects, it is the most massive compact infrared object in the central region, located at 2.″0 of the symmetry center of the galactic bar, as measured in the K-band emission. Moreover, our data indicate that this object is surrounded by a large circumnuclear stellar disk and it is also located at the rotation center of the large molecular gas disk of NGC 253. Furthermore, a kinematic residual appears in the H{sub 2} rotation curve with a sinusoidal shape consistent with an outflow centered in the candidate nucleus position. The maximum outflow velocity is located about 14 pc from TH7, which is consistent with the radius of a shell detected around the nucleus candidate, observed at 18.3 μm (Qa) and 12.8 μm ([Ne ii]) with T-ReCS. Also, the Brγ emission line profile shows a pronounced blueshift and this emission line also has the highest equivalent width at this

  12. Probing the space-time geometry around black hole candidates with the resonance models for high-frequency QPOs and comparison with the continuum-fitting method

    International Nuclear Information System (INIS)

    Astrophysical black hole candidates are thought to be the Kerr black hole predicted by General Relativity. However, in order to confirm the Kerr-nature of these objects, we need to probe the geometry of the space-time around them and check that observations are consistent with the predictions of the Kerr metric. That can be achieved, for instance, by studying the properties of the electromagnetic radiation emitted by the gas in the accretion disk. The high-frequency quasi-periodic oscillations observed in the X-ray flux of some stellar-mass black hole candidates might do the job. As the frequencies of these oscillations depend only very weakly on the observed X-ray flux, it is thought they are mainly determined by the metric of the space-time. In this paper, I consider the resonance models proposed by Abramowicz and Kluzniak and I extend previous results to the case of non-Kerr space-times. The emerging picture is more complicated than the one around a Kerr black hole and there is a larger number of possible combinations between different modes. I then compare the bounds inferred from the twin peak high-frequency quasi-periodic oscillations observed in three micro-quasars (GRO J1655-40, XTE J1550-564, and GRS 1915+105) with the measurements from the continuum-fitting method of the same objects. For Kerr black holes, the two approaches do not provide consistent results. In a non-Kerr geometry, this conflict may be solved if the observed quasi-periodic oscillations are produced by the resonance νθ:νr = 3:1, where νθ and νr are the two epicyclic frequencies. It is at least worth mentioning that the deformation from the Kerr solution required by observations would be consistent with the one suggested in another recent work discussing the possibility that steady jets are powered by the spin of these compact objects

  13. ARIEL: an ESA M4 mission candidate

    Science.gov (United States)

    Puig, L.; Pilbratt, G. L.; Heske, A.; Escudero Sanz, I.; Crouzet, P.-E.

    2016-07-01

    The Atmospheric Remote sensing Infrared Exoplanet Large survey (ARIEL) mission is an M-class mission candidate within the science program Cosmic Vision of the European Space Agency (ESA). It was selected in June 2015 as one of three candidates to enter an assessment phase (phase 0/A). This process involves the definition of science and mission requirements as well as a preliminary model payload, and an internal Concurrent Design Facility (CDF) study providing the input to parallel industrial studies (in progress since 2016). After this process, the three candidates will be reviewed and in mid-2017 one of them will be selected as the M4 mission for launch in 2026. ARIEL is a survey-type mission dedicated to the characterisation of exoplanetary atmospheres. Using the differential technique of transit spectroscopy, ARIEL will obtain transmission and/or emission spectra of the atmospheres of a large and diverse sample of known exoplanets (~500) covering a wide range of masses, densities, equilibrium temperatures, orbital properties and host-star characteristics. This will include hot Jupiters to warm Super-Earths, orbiting M5 to F0 stars. This paper describes critical requirements, and reports on the results of the Concurrent Design Facility (CDF) study that was conducted in June / July 2015, providing a description of the resulting spacecraft design. It will employ a 0.7 m x 1.1 m off-axis three mirror telescope, feeding four photometric channels in the VNIR range (0.5-1.95 μm) and an IR spectrometer covering 1.95-7.8 μm.

  14. Dark Matter and its Particle Candidates

    CERN Document Server

    Bottino, A

    1999-01-01

    In these lectures we first briefly review the main observational facts which imply that most part of matter in the Universe is not visible and some recent intriguing experimental data which would point to a significant contribution to Omega due to a cosmological constant. We subsequently discuss some particle candidates for dark matter, with particular emphasis for the neutralino. We present the main properties of this particle, also in the light of the most recent experimental results in direct search for relic particles; furthermore, we discuss the perspectives for their indirect searches.

  15. Blend Analysis of HATNet Transit Candidates

    Directory of Open Access Journals (Sweden)

    Bakos G.Á.

    2011-02-01

    Full Text Available Candidate transiting planet systems discovered by wide-field groundbased surveys must go through an intensive follow-up procedure to distinguish the true transiting planets from the much more common false positives. Especially pernicious are configurations of three or more stars which produce radial velocity and light curves that are similar to those of single stars transited by a planet. In this contribution we describe the methods used by the HATNet team to reject these blends, giving a few illustrative examples.

  16. Candidate gene effects on beef quality

    OpenAIRE

    Ekerljung, Marie

    2012-01-01

    The contribution of five candidate genes to the variation in meat tenderness, pH, colour, marbling and water holding capacity (WHC) was analysed in muscle samples from 243 young bulls of Angus, Charolais, Hereford, Limousin, or Simmental breed, raised in Swedish commercial herds. The animals were genotyped for single nucleotide polymorphisms (SNPs) in the genes encoding calpain 1 (CAPN1:c.947G>C), calpastatin, (CAST:c.155C>T), diacylglycerol O-acyltransferase 1 (DGAT1), leptin (UASMS2C>T) a...

  17. Reducing stigma and discrimination: Candidate interventions

    Directory of Open Access Journals (Sweden)

    Kassam Aliya

    2008-04-01

    Full Text Available Abstract This paper proposes that stigma in relation to people with mental illness can be understood as a combination of problems of knowledge (ignorance, attitudes (prejudice and behaviour (discrimination. From a literature review, a series of candidate interventions are identified which may be effective in reducing stigmatisation and discrimination at the following levels: individuals with mental illness and their family members; the workplace; and local, national and international. The strongest evidence for effective interventions at present is for (i direct social contact with people with mental illness at the individual level, and (ii social marketing at the population level.

  18. Top Zika Vaccine Candidate Moves Closer to Field Testing

    Science.gov (United States)

    ... https://medlineplus.gov/news/fullstory_161274.html Top Zika Vaccine Candidate Moves Closer to Field Testing DNA- ... MONDAY, Oct. 3, 2016 (HealthDay News) -- The leading Zika vaccine candidate should be ready for field testing ...

  19. Nonclinical Development of BCG Replacement Vaccine Candidates

    Directory of Open Access Journals (Sweden)

    Bernd Eisele

    2013-04-01

    Full Text Available The failure of current Mycobacterium bovis bacille Calmette–Guérin (BCG vaccines, given to neonates to protect against adult tuberculosis and the risk of using these live vaccines in HIV-infected infants, has emphasized the need for generating new, more efficacious and safer replacement vaccines. With the availability of genetic techniques for constructing recombinant BCG (rBCG strains containing well-defined gene deletions or insertions, new vaccine candidates are under evaluation at both the preclinical and clinical stages of development. Since most BCG vaccines in use today were evaluated in clinical trials decades ago and are produced by outdated processes, the development of new BCG vaccines offers a number of advantages that include a modern well-defined manufacturing process along with state-of-the-art evaluation of safety and efficacy in target populations. We provide a description of the preclinical development of two novel rBCGs, VPM1002 that was constructed by adding a modified hly gene coding for the protein listeriolysin O (LLO from Listeria monocytogenes and AERAS-422, which carries a modified pfoA gene coding for the protein perfringolysin O (PFO from Clostridium perfringens, and three genes from Mycobacterium tuberculosis. Novel approaches like these should be helpful in generating stable and effective rBCG vaccine candidates that can be better characterized than traditional BCG vaccines.

  20. Pulsar Candidates Toward Fermi Unassociated Sources

    CERN Document Server

    Frail, D A; Jagannathan, P; Intema, H T

    2016-01-01

    We report on a search for steep spectrum radio sources within the 95% confidence error ellipses of the Fermi unassociated sources from the Large Array Telescope (LAT). Using existing catalogs and the newly released GMRT all-sky survey at 150 MHz we identify compact radio sources that are bright at MHz frequencies but faint or absent at GHz frequencies. Such steep spectrum radio sources are rare and constitute a sample of pulsar candidates, selected independently of period, dispersion measure, interstellar scattering and orbital parameters. We find point-like, steep spectrum candidates toward 11 Fermi sources. Based on the gamma-ray/radio positional coincidence, the rarity of such radio sources, and the properties of the 3FGL sources themselves, we argue that many of these sources could be pulsars. They may have been missed by previous radio periodicity searches due to interstellar propagation effects or because they lie in an unusually tight binary. If this hypothesis is correct, then renewed gamma-ray and ra...

  1. Advanced vaccine candidates for Lassa fever.

    Science.gov (United States)

    Lukashevich, Igor S

    2012-11-01

    Lassa virus (LASV) is the most prominent human pathogen of the Arenaviridae. The virus is transmitted to humans by a rodent reservoir, Mastomys natalensis, and is capable of causing lethal Lassa Fever (LF). LASV has the highest human impact of any of the viral hemorrhagic fevers (with the exception of Dengue Fever) with an estimated several hundred thousand infections annually, resulting in thousands of deaths in Western Africa. The sizeable disease burden, numerous imported cases of LF in non-endemic countries, and the possibility that LASV can be used as an agent of biological warfare make a strong case for vaccine development. Presently there is no licensed vaccine against LF or approved treatment. Recently, several promising vaccine candidates have been developed which can potentially target different groups at risk. The purpose of this manuscript is to review the LASV pathogenesis and immune mechanisms involved in protection. The current status of pre-clinical development of the advanced vaccine candidates that have been tested in non-human primates will be discussed. Major scientific, manufacturing, and regulatory challenges will also be considered. PMID:23202493

  2. Advanced Vaccine Candidates for Lassa Fever

    Science.gov (United States)

    Lukashevich, Igor S.

    2012-01-01

    Lassa virus (LASV) is the most prominent human pathogen of the Arenaviridae. The virus is transmitted to humans by a rodent reservoir, Mastomys natalensis, and is capable of causing lethal Lassa Fever (LF). LASV has the highest human impact of any of the viral hemorrhagic fevers (with the exception of Dengue Fever) with an estimated several hundred thousand infections annually, resulting in thousands of deaths in Western Africa. The sizeable disease burden, numerous imported cases of LF in non-endemic countries, and the possibility that LASV can be used as an agent of biological warfare make a strong case for vaccine development. Presently there is no licensed vaccine against LF or approved treatment. Recently, several promising vaccine candidates have been developed which can potentially target different groups at risk. The purpose of this manuscript is to review the LASV pathogenesis and immune mechanisms involved in protection. The current status of pre-clinical development of the advanced vaccine candidates that have been tested in non-human primates will be discussed. Major scientific, manufacturing, and regulatory challenges will also be considered. PMID:23202493

  3. Advanced Vaccine Candidates for Lassa Fever

    Directory of Open Access Journals (Sweden)

    Igor S. Lukashevich

    2012-10-01

    Full Text Available Lassa virus (LASV is the most prominent human pathogen of the Arenaviridae. The virus is transmitted to humans by a rodent reservoir, Mastomys natalensis, and is capable of causing lethal Lassa Fever (LF. LASV has the highest human impact of any of the viral hemorrhagic fevers (with the exception of Dengue Fever with an estimated several hundred thousand infections annually, resulting in thousands of deaths in Western Africa. The sizeable disease burden, numerous imported cases of LF in non-endemic countries, and the possibility that LASV can be used as an agent of biological warfare make a strong case for vaccine development. Presently there is no licensed vaccine against LF or approved treatment. Recently, several promising vaccine candidates have been developed which can potentially target different groups at risk. The purpose of this manuscript is to review the LASV pathogenesis and immune mechanisms involved in protection. The current status of pre-clinical development of the advanced vaccine candidates that have been tested in non-human primates will be discussed. Major scientific, manufacturing, and regulatory challenges will also be considered.

  4. Serological profile of candidates for corneal donation

    Directory of Open Access Journals (Sweden)

    Adroaldo Lunardelli

    2014-10-01

    Full Text Available Objetive: The purpose of this study is to map the serological profile of candidates to corneal donation at Irmandade Santa Casa de Misericórdia de Porto Alegre, identifying the percentage of disposal by serology and the marker involved. Methods: There have been analised – retrospectively – the results of serology of all corneal donors, made between the period of 1st january 2006 and 31st december 2012. Data analised were related to age, gender and the results of serology pertinent to viral markers (HBsAg, anti-HBc, anti-HCV and anti-HIV, these, determined by immunosorbent tests (ELISA. Results: In the period of the study, there were 2476 corneal donors at the institution, with a major incidence on the male gender, on an average of 58.7 years old. 23% of retention because of serological unfitness was also identified, that is, 570 samples were non-negative to any of the used tests. The marker anti- HBc was the most prevalent on the studied population, followed by the Hepatitis C virus (HCV and by the Human Immunodeficiency Virus (HIV. Conclusion: From the data found through this study, it is essential to have the participation of an efficient service on the serological evaluation of the candidates to corneal donation, once the security of the receptor must be taken into consideration in a population of donors with 23% of unfitness prevalence, in which the most prevalent marker is the one of Hepatits B.

  5. Elemental Abundances of Solar Sibling Candidates

    CERN Document Server

    Ramirez, I; Bobylev, V V; Roederer, I U; Lambert, D L; Endl, M; Cochran, W D; MacQueen, P J; Wittenmyer, R A

    2014-01-01

    Dynamical information along with survey data on metallicity and in some cases age have been used recently by some authors to search for candidates of stars that were born in the cluster where the Sun formed. We have acquired high resolution, high signal-to-noise ratio spectra for 30 of these objects to determine, using detailed elemental abundance analysis, if they could be true solar siblings. Only two of the candidates are found to have solar chemical composition. Updated modeling of the stars' past orbits in a realistic Galactic potential reveals that one of them, HD162826, satisfies both chemical and dynamical conditions for being a sibling of the Sun. Measurements of rare-element abundances for this star further confirm its solar composition, with the only possible exception of Sm. Analysis of long-term high-precision radial velocity data rules out the presence of hot Jupiters and confirms that this star is not in a binary system. We find that chemical tagging does not necessarily benefit from studying a...

  6. Vaccine candidates for leishmaniasis: a review.

    Science.gov (United States)

    Nagill, Rajeev; Kaur, Sukhbir

    2011-10-01

    Leishmaniasis is a diverse group of clinical syndromes caused by protozoan parasites of the genus Leishmania. The clinical manifestation of the disease varies from self-limiting cutaneous lesions to progressive visceral disease. It is estimated that 350 million people are at risk in 88 countries, with a global incidence of 1-1.5 million cases of cutaneous and 500,000 cases of visceral leishmaniasis. The key control measures mainly rely on early case detection and chemotherapy which has been hampered by the toxicity of drugs, side-effects and by the emergence of drug resistance in parasites. Control of reservoir host and vector is difficult due to operational difficulties and frequent relapses in the host. Therefore, the development of effective and affordable vaccine against leishmaniasis is highly desirable. Although considerable progress has been made over the last decade in understanding immune mechanisms underlying potential candidate antigens, including killed, live attenuated parasites, crude parasites, pure or recombinant Leishmania proteins or DNA encoding leishmanial proteins, as well as immunomodulators from sand fly saliva, very few candidate vaccines have progressed beyond the experimental stage. As such there is no vaccine against any form of human leishmaniasis. In recent years, however, much interest has been stimulated towards vaccination against leishmaniasis focused mainly on cutaneous leishmaniasis with fewer attempts against visceral leishmaniasis.

  7. Nonclinical Development of BCG Replacement Vaccine Candidates.

    Science.gov (United States)

    Velmurugan, Kamalakannan; Grode, Leander; Chang, Rosemary; Fitzpatrick, Megan; Laddy, Dominick; Hokey, David; Derrick, Steven; Morris, Sheldon; McCown, David; Kidd, Reginald; Gengenbacher, Martin; Eisele, Bernd; Kaufmann, Stefan H E; Fulkerson, John; Brennan, Michael J

    2013-01-01

    The failure of current Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccines, given to neonates to protect against adult tuberculosis and the risk of using these live vaccines in HIV-infected infants, has emphasized the need for generating new, more efficacious and safer replacement vaccines. With the availability of genetic techniques for constructing recombinant BCG (rBCG) strains containing well-defined gene deletions or insertions, new vaccine candidates are under evaluation at both the preclinical and clinical stages of development. Since most BCG vaccines in use today were evaluated in clinical trials decades ago and are produced by outdated processes, the development of new BCG vaccines offers a number of advantages that include a modern well-defined manufacturing process along with state-of-the-art evaluation of safety and efficacy in target populations. We provide a description of the preclinical development of two novel rBCGs, VPM1002 that was constructed by adding a modified hly gene coding for the protein listeriolysin O (LLO) from Listeria monocytogenes and AERAS-422, which carries a modified pfoA gene coding for the protein perfringolysin O (PFO) from Clostridium perfringens, and three genes from Mycobacterium tuberculosis. Novel approaches like these should be helpful in generating stable and effective rBCG vaccine candidates that can be better characterized than traditional BCG vaccines. PMID:26343962

  8. Candidate chemosensory cells in the porcine stomach.

    Science.gov (United States)

    Widmayer, Patricia; Breer, Heinz; Hass, Nicole

    2011-07-01

    A continuous chemosensory monitoring of the ingested food is of vital importance for adjusting digestive processes according to diet composition. Although any dysfunction of this surveillance system may be the cause of severe gastrointestinal disorders, information about the cellular and molecular basis of chemosensation in the gastrointestinal tract is limited. The porcine alimentary canal is considered as an appropriate model for the human gastrointestinal tract. Therefore, in this study we have investigated the gastric mucosa of swine for cells which express gustatory transduction elements such as TRPM5 or PLCβ2, and thus may represent candidate "chemosensors". It was found that the porcine stomach indeed contains cells expressing gustatory marker molecules; however, the morphology and topographic distribution of putative chemosensory cells varied significantly from that in mice. Whereas in the murine stomach these cells were clustered at a distinct region near the gastric entrance, no such compact cell cluster was found in the pig stomach. These results indicate substantial differences regarding the phenotype of candidate chemosensory cells of mice and swine and underline the importance of choosing the most suitable model organisms. PMID:21667283

  9. Criteria for candidate species for aquaculture

    Energy Technology Data Exchange (ETDEWEB)

    Webber, H.H.; Riordan, P.F.

    1976-01-01

    The nature of the animal taxa that are the most probable candidates for an intensive, commercial aquatic animal husbandry industry is considered. A characterization is presented of those biological criteria that lend the species the necessary physiological and genetic malleability to be adapted and molded into a domesticated race. The animal cultivated must be amenable to intensive management in high-density confinements such as those now being engineered for high-yield aquaculture. Attributes considered are discussed in the context of the various aquacultural ecosystems in which the specific biotype is expected to achieve satisfactory growth and survival. Correlative with bionomic criteria, economic requirements are posed and evaluated in an effort to define a socially and financially profitable agribusiness system. Investment requirements and operating costs are considered in terms of expected returns. However, since production alone is insufficient to sustain an enterprise - i.e., the product must be sold - production costs must be judged against market values. Therefore, ultimate use or consumer acceptance criteria are incorporated into the list of essential requirements for a candidate species for aquafarming.

  10. CASE via MS: Ranking Structure Candidates by Mass Spectra

    OpenAIRE

    Kerber, Adalbert; Meringer, Markus; Rücker, Christoph

    2006-01-01

    Two important tasks in computer-aided structure elucidation (CASE) are the generation of candidate structures from a given molecular formula, and the ranking of structure candidates according to compatibility with an experimental spectrum. Candidate ranking with respect to electron impact mass spectra is based on virtual fragmentation of a candidate structure and comparison of the fragments’ isotope distributions against the spectrum of the unknown compound, whence a structure–spectrum compat...

  11. Encouraging Discussion between Teacher Candidates and Families with Exceptional Children

    Science.gov (United States)

    Williams, Emily

    2012-01-01

    The Families as Faculty experience assists universities to better prepare candidates for service as classroom teachers. Upon entering their practica and student teaching, many teacher candidates have had no to limited contact with exceptional students. Often candidates are unaware of the realities of having a student with disabilities in their…

  12. Views on Values Education: From Teacher Candidates to Experienced Teachers

    Science.gov (United States)

    Iscan, Canay Demirhan

    2015-01-01

    This study aimed to identify the views of experienced class teachers and class teacher candidates on values education. It conducted standard open-ended interviews with experienced class teachers and teacher candidates. The study group comprised 9 experienced class teachers from different socio-economic levels and 9 teacher candidates with…

  13. Opinions of the Geography Teacher Candidates toward Mind Maps

    Science.gov (United States)

    Seyihoglu, Aysegul

    2013-01-01

    The purpose of this study is to reveal the opinions of the teacher candidates about mind mapping technique used in Geography education of undergraduate program. In this study, the qualitative research techniques were used. The study group consists of 55 teacher candidates. The teacher candidates have been asked for their opinions about the process…

  14. Identity Functions and Empathetic Tendencies of Teacher Candidates

    Science.gov (United States)

    Ay, Alpaslan; Kadi, Aysegul

    2016-01-01

    Objective of this research is to investigate identity functions and empathetic tendencies of teacher candidates. Sample consists of 232 teacher candidates in social studies teacher education. Survey model is preferred to investigate the difference between identity functions and empathetic tendencies of teacher candidates. And also correlational…

  15. Mirror Images: Teacher Candidates' Perceptions of Disposition Development

    Science.gov (United States)

    Bercaw, Lynne A.; Summers, Deborah G.; Colby, Susan A.; Payne, Maggie

    2012-01-01

    The complexity of disposition development for teacher candidates continues to be discussed and debated in teacher education. This study compares two programs and the different ways each approaches the disposition development of their respective candidates. More than 200 candidates from two institutions were surveyed on how and where they perceived…

  16. Production of EV71 vaccine candidates.

    Science.gov (United States)

    Chong, Pele; Hsieh, Shih-Yang; Liu, Chia-Chyi; Chou, Ai-Hsiang; Chang, Jui-Yuan; Wu, Suh-Chin; Liu, Shih-Jen; Chow, Yen-Hung; Su, Ih-Jen; Klein, Michel

    2012-12-01

    Enterovirus 71 (EV71) is now recognized as an emerging neurotropic virus in Asia and with Coxsackie virus (CV) it is the other major causative agent of hand-foot-mouth diseases (HFMD). Effective medications and/or prophylactic vaccines against HFMD are urgently needed. From a scientific (the feasibility of bioprocess, immunological responses and potency in animal challenge model) and business development (cost of goods) points of view, we in this review address and discuss the pros and cons of different EV71 vaccine candidates that have been produced and evaluated in animal models. Epitope-based synthetic peptide vaccine candidates containing residues 211-225 of VP1 formulated with Freund's adjuvant (CFA/IFA) elicited low EV71 virus neutralizing antibody responses, but were protective in the suckling mouse challenge model. Among recombinant EV71 subunits (rVP1, rVP2 and rVP3) expressed in E. coli, purified and formulated with CFA/IFA, only VP1 elicited mouse antibody responses with measurable EV71-specific virus neutralization titers. Immunization of mice with either a DNA plasmid containing VP1 gene or VP1 expressed in Salmonella typhimurium also generated neutralizing antibody responses and protected animals against a live EV71 challenge. Recombinant EV71 virus-like particles (rVLP) produced from baculovirus formulated either with CFA/IFA or alum elicited good virus neutralization titers in both mice and non-human primates, and were found to be protective in the suckling mouse EV71 challenge model. Synthetic peptides or recombinant EV71 subunit vaccines (rVP1 and rVLP) formulated in alum were found to be poorly immunogenic in rabbits. Only formalin-inactivated (FI) EV71 virions formulated in alum elicited cross-neutralizing antibodies against different EV71 genotypes in mice, rabbits and non-human primates but induced weak neutralizing responses against CAV16. From a regulatory, economic and market acceptability standpoint, FI-EV71 virion vaccines are the most

  17. A direct molecular link between the autism candidate gene RORa and the schizophrenia candidate MIR137

    Science.gov (United States)

    Devanna, Paolo; Vernes, Sonja C.

    2014-02-01

    Retinoic acid-related orphan receptor alpha gene (RORa) and the microRNA MIR137 have both recently been identified as novel candidate genes for neuropsychiatric disorders. RORa encodes a ligand-dependent orphan nuclear receptor that acts as a transcriptional regulator and miR-137 is a brain enriched small non-coding RNA that interacts with gene transcripts to control protein levels. Given the mounting evidence for RORa in autism spectrum disorders (ASD) and MIR137 in schizophrenia and ASD, we investigated if there was a functional biological relationship between these two genes. Herein, we demonstrate that miR-137 targets the 3'UTR of RORa in a site specific manner. We also provide further support for MIR137 as an autism candidate by showing that a large number of previously implicated autism genes are also putatively targeted by miR-137. This work supports the role of MIR137 as an ASD candidate and demonstrates a direct biological link between these previously unrelated autism candidate genes.

  18. ELECTIONS PENSION FUND CANDIDATE NR 4

    CERN Multimedia

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate : Name : MYERS First Name : Stephen I have been at CERN since 1972, and was elected member of the Governing Board for the first time in 1998. The Governing Board then nominated me to the Investments Committee where I have been a member since the beginning of 1999. Since then I have actively participated in redefining and transforming the investment portfolio in order to improve the overall return and where possible reduce the risk. The portfolio has recently been greatly improved and now allows much simpler more transparent monitoring of our investment. I have also actively participated and hopefully made useful contributions in discussions conc...

  19. ELECTIONS PENSION FUND 4th candidate

    CERN Multimedia

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate : Name : MYERS First Name : Stephen I have been at CERN since 1972, and was elected member of the Governing Board for the first time in 1998. The Governing Board then nominated me to the Investments Committee where I have been a member since the beginning of 1999. Since then I have actively participated in redefining and transforming the investment portfolio in order to improve the overall return and where possible reduce the risk. The portfolio has recently been greatly improved and now allows much simpler more transparent monitoring of our investment. I have also actively participated and hopefully made useful contributions in discussions conc...

  20. New potential AChE inhibitor candidates.

    Science.gov (United States)

    de Paula, A A N; Martins, J B L; dos Santos, M L; Nascente, L de C; Romeiro, L A S; Areas, T F M A; Vieira, K S T; Gambôa, N F; Castro, N G; Gargano, R

    2009-09-01

    We have theoretically studied new potential candidates of acetylcholinesterase (AChE) inhibitors designed from cardanol, a non-isoprenoid phenolic lipid of cashew Anacardium occidentale nut-shell liquid. The electronic structure calculations of fifteen molecule derivatives from cardanol were performed using B3LYP level with 6-31G, 6-31G(d), and 6-311+G(2d,p) basis functions. For this study we used the following groups: methyl, acetyl, N,N-dimethylcarbamoyl, N,N-dimethylamine, N,N-diethylamine, piperidine, pyrrolidine, and N,N-methylbenzylamine. Among the proposed compounds we identified that the structures with substitution by N,N-dimethycarbamoyl, N,N-dimethylamine, and pyrrolidine groups were better correlated to rivastigmine, and represent possible AChE inhibitors against Alzheimer disease. PMID:19446931

  1. ELECTIONS PENSION FUND 3rd candidate

    CERN Multimedia

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate : Name : Hauviller First Name : Claude Dear colleague of CERN and ESO, For the first time, I am standing and requesting your support to become a member of the Governing Board of our Pension Fund. CERN staff member since 1974, I have already carried elective mandates: I have been Delegate to the Staff Council and Member of the Senior Staff Consultative Committee (the Nine). For the majority of us, our Pension Fund is our only social provident scheme and source of retirement income; I believe I can usefully contribute to its successful management and help ensure its balance. Our Fund reaches its majority: soon, there will be more beneficiaries tha...

  2. ELECTIONS PENSION FUND CANDIDATE NR 3

    CERN Multimedia

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate : Name : HAUVILLER First Name : Claude Dear colleague of CERN and ESO, For the first time, I am standing and requesting your support to become a member of the Governing Board of our Pension Fund. CERN staff member since 1974, I have already carried elective mandates: I have been Delegate to the Staff Council and Member of the Senior Staff Consultative Committee (the Nine). For the majority of us, our Pension Fund is our only social provident scheme and source of retirement income; I believe I can usefully contribute to its successful management and help ensure its balance. Our Fund reaches its majority: soon, there will be more beneficiaries tha...

  3. Halopentacenes: Promising Candidates for Organic Semiconductors

    Institute of Scientific and Technical Information of China (English)

    DU Gong-He; REN Zhao-Yu; GUO Ping; ZHENG Ji-Ming

    2009-01-01

    We introduce polar substituents such as F, Cl, Br into pentacene to enhance the dissolubility in common organic solvents while retaining the high charge-carrier mobilities of pentacene. Geometric structures, dipole moments,frontier molecule orbits, ionization potentials and electron affinities, as well as reorganization energies of those molecules, and of pentacene for comparison, are successively calculated by density functional theory. The results indicate that halopentacenes have rather small reorganization energies (< 0.2 eV), and when the substituents are in position 2 or positions 2 and 9, they are polarity molecules. Thus we conjecture that they can easily be dissolved in common organic solvents, and are promising candidates for organic semiconductors.

  4. Radion Candidate for the LHC Diphoton Resonance

    CERN Document Server

    Bardhan, Debjyoti; Chakraborty, Amit; Maitra, Ushoshi; Raychaudhuri, Sreerup; Samui, Tousik

    2015-01-01

    The recent observation of a modest excess in diphoton final states at the LHC, by both the ATLAS and CMS Collaborations, has sparked off the expected race among theorists to find the right explanation for this proto-resonance, assuming that the signal will survive and not prove to be yet another statistical fluctuation. We carry out a general analysis of this `signal' in the case of a scalar which couples only to pairs of gluons (for production) and photons (for diphoton decay modes), and establish that an explanation of the observed resonance, taken together with the null results of new physics searches in all the other channels, requires a scalar with rather exotic behaviour. We then demonstrate that a fairly simple-minded extension of the minimal Randall-Sundrum model can yield a radion candidate which might reproduce this exotic behaviour.

  5. Pituitary stem cells: candidates and implications.

    Science.gov (United States)

    Nassiri, Farshad; Cusimano, Michael; Zuccato, Jeff A; Mohammed, Safraz; Rotondo, Fabio; Horvath, Eva; Syro, Luis V; Kovacs, Kalman; Lloyd, Ricardo V

    2013-09-01

    The pituitary is the master endocrine gland of the body. It undergoes many changes after birth, and these changes may be mediated by the differentiation of pituitary stem cells. Stem cells in any tissue source must display (1) pluripotent capacity, (2) capacity for indefinite self-renewal, and (3) a lack of specialization. Unlike neural stem cells identified in the hippocampus and subventricular zone, pituitary stem cells are not associated with one specific cell type. There are many major candidates that are thought to be potential pituitary stem cell sources. This article reviews the evidence for each of the major cell types and discuss the implications of identifying a definitive pituitary stem cell type. PMID:23423660

  6. Hypervelocity Star Candidates in the SEGUE G & K Dwarf Sample

    CERN Document Server

    Palladino, Lauren E; Holley-Bockelmann, Kelly; Prieto, Carlos Allende; Beers, Timothy C; Lee, Young Sun; Schneider, Donald P

    2013-01-01

    We identify 13 candidate hypervelocity stars from the Sloan Extension for Galactic Understanding and Exploration (SEGUE) G and K dwarf samples. Previous searches for hypervelocity stars have only focused on large radial velocities; in this study we also use proper motions to select the candidates. We determine the hypervelocity likelihood of each candidate, considering the significant errors often associated with high proper motion stars via Monte Carlo simulations. We find that more than half of the candidates exceed their escape velocities with at least 90% probability. All of our candidates also have less than a 60% chance of being a high velocity fluke within the SEGUE sample. Based on orbits calculated using the observed 6-d positions and velocities, few, if any, of these candidates originate from the Galactic Center. If these candidates are truly hypervelocity stars, they were not ejected by interactions with the Milky Way's supermassive black hole. This calls for a more serious examination of alternati...

  7. Comet candidates among quasi-Hilda objects

    Science.gov (United States)

    Gil-Hutton, R.; García-Migani, E.

    2016-05-01

    Aims: We present the results of a search for quasi-Hilda comets. We wanted to find objects that have recently arrived from the Centaur zone that could became active near the perihelion of their orbits. Methods: Two hundred and seventy-seven objects from the ASTORB database were selected following a dynamical criteria to constrain the unstable quasi-Hilda region. These objects were integrated backward 50 000 yr in order to identify those that have recently arrived from the outer regions of the solar system. Results: The backward integration showed that 11 objects could be Centaurs or transneptunian objects that ended their dynamical evolution as quasi-Hilda comets. The dynamical evolution of these objects from a statistical point of view was studied by computing the time-averaged distribution of a number of clones as a function of the aphelion and perihelion distances. All the candidates show a dynamical behavior that is expected for comets injected in the inner solar system from the Centaur or transneptunian regions and reaching the quasi-Hilda region.

  8. Virus-like particles as nanovaccine candidates

    International Nuclear Information System (INIS)

    The existing vaccines are mainly limited to the microorganisms we are able to culture and produce and/or to those whose killing is mediated by humoral response (antibody mediated). It has been more difficult to develop vaccines capable of inducing a functional cellular response needed to prevent or cure chronic diseases. New strategies should be taken into account in the improvement of cell-based immune responses in order to prevent and control the infections and eventually clear the virus. Preclinical and clinical results with vaccine candidates developed as a vaccine platform based on virus-like particles (VLPs) evidenced their ability to stimulate mucosal as well as systemic immunity. Particles based on envelope, membrane or nucleocapsid microbial proteins induce a strong immune response after nasal or parenteral administration in mice, non-human primates and humans. In addition, the immune response obtained was modulated in a Th1 sense. The VLPs were also able to immunoenhance the humoral and cellular immune responses against several viral pathogens. Studies in animals and humans with nasal and systemic formulations evidenced that it is possible to induce functional immune response against HBV, HCV, HIV and dengue virus. (paper)

  9. Genetic markers: Potential candidates for cardiovascular disease.

    Science.gov (United States)

    Rather, Riyaz Ahmad; Dhawan, Veena

    2016-10-01

    The effective prevention of cardiovascular disease depends upon the ability to recognize the high-risk individuals at an early stage of the disease or long before the development of adverse events. Evolving technologies in the fields of proteomics, metabolomics, and genomics have played a significant role in the discovery of cardiovascular biomarkers, but so far these methods have achieved the modest success. Hence, there is a crucial need for more reliable, suitable, and lasting diagnostic and therapeutic markers to screen the disease well in time to start the clinical aid to the patients. Gene polymorphisms associated with the cardiovascular disease play a decisive role in the disease onset. Therefore, the genetic marker evaluation to classify high-risk patients from low-risk patients trends an effective approach to patient management and care. Currently, there are no genetic markers available for extensive adoption as risk factors for coronary vascular disease, yet, there are numerous promising, biologically acceptable candidates. Many of these gene biomarkers, alone or in combination, can play an essential role in the prediction of cardiovascular risk. The present review highlights some putative emerging genetic biomarkers that could facilitate more authentic and fast diagnosis of CVD. This review also briefly describes few technological approaches employed in the biomarker search. PMID:27416153

  10. ELECTIONS PENSION FUND CANDIDATE NR 1

    CERN Multimedia

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate : Name : CHIAVERI First Name : Enrico I have been a CERN staff member since 1973 and have always been interested in our working conditions. As a member of the Executive Committee of the Staff Association I participated from 1980 to 1984 in the Working Group on Pensions mandated by the CERN Council. This commitment led to my becoming a member of the Governing Board of the Pension Fund in 1983, since when I have taken an active part in various commissions and working groups (Real Estate Asset Management Committee, Working Group on Actuarial Matters etc.); in so doing I have gained a thorough knowledge of different areas of the Pension Fund. Since ...

  11. Galactic worms. I - Catalog of worm candidates

    Science.gov (United States)

    Koo, Bon-Chul; Heiles, Carl; Reach, William T.

    1992-01-01

    A catalog of candidates for the Galactic worms that are possibly the walls surrounding the superbubbles is compiled; 118 isolated structures that appear both in H I and in IR (60 and 100 microns). Fifty-two are possibly associated with H II regions. It is found that the 100-micron emissivity increases systematically toward the Galactic interior, which is consistent with the increase of the general interstellar radiation field. The 100-micron emissivity of the structures associated with the H II regions is larger than that of the structures without associated H II regions. The 60-100-micron ratio is large, 0.28 +/- 0.03, which may indicate that the grains associated with the atomic gas have a relatively large population of small grains. Thirty-five structures appear in the 408-MHz continuum. The IR and the radio continuum properties suggest that the 408-MHz continuum emission in those structures is very likely thermal. The implications of these results on the ionization of gas far from the Galactic plane are discussed.

  12. An evaluation of candidate oxidation resistant materials

    Science.gov (United States)

    Rutledge, Sharon; Banks, Bruce; Mirtich, Michael; Difilippo, Frank; Hotes, Deborah; Labed, Richard; Dever, Terese; Kussmaul, Michael

    1987-01-01

    Ground based testing of materials considered for Kapton solar array blanket protection, graphite epoxy structural member protection, and high temperature radiators was performed in an RF plasma asher. Ashing rates for Kapton were correlated with rates measured on STS-8 to determine the exposure time equivalent to one year in low Earth orbit (LEO) at a constant density space station orbital flux. Protective coatings on Kapton from Tekmat, Andus Corporation, and LeRC were evaluated in the plasma asher and mass loss rates per unit area were measured for each sample. All samples evaluated provided some protection to the underlying surface but ion beam sputter deposited samples of SiO2 and SiO2 with 8% polytetrafluoroethylene (PTFE) showed no evidence of degradation after 47 hours of exposure. Mica paint was evaluated as a protective coating for graphite epoxy structural members. Mica appears to be resistant to attack by atomic oxygen but only offers some limited protection as a paint because the paint vehicles evaluated to date were not resistant to atomic oxygen. Four materials were selected for evaluation as candidate radiator materials: stainless steel, copper, niobium-1% zirconium, and titanium-6% aluminum-4% vanadium. These materials were surface textured by various means to improve their emittance. Emittances as high as 0.93 at 2.5 microns for stainless steel and 0.89 at 2.5 microns for Nb-1 Zr were obtained from surface texturing. There were no significant changes in emittance after asher exposure.

  13. Virus-like particles as nanovaccine candidates

    Science.gov (United States)

    Guillen, G.; Aguilar, J. C.; Dueñas, S.; Hermida, L.; Iglesias, E.; Penton, E.; Lobaina, Y.; Lopez, M.; Mussachio, A.; Falcon, V.; Alvarez, L.; Martinez, G.; Gil, L.; Valdes, I.; Izquierdo, A.; Lazo, L.; Marcos, E.; Guzman, G.; Muzio, V.; Herrera, L.

    2013-03-01

    The existing vaccines are mainly limited to the microorganisms we are able to culture and produce and/or to those whose killing is mediated by humoral response (antibody mediated). It has been more difficult to develop vaccines capable of inducing a functional cellular response needed to prevent or cure chronic diseases. New strategies should be taken into account in the improvement of cell-based immune responses in order to prevent and control the infections and eventually clear the virus. Preclinical and clinical results with vaccine candidates developed as a vaccine platform based on virus-like particles (VLPs) evidenced their ability to stimulate mucosal as well as systemic immunity. Particles based on envelope, membrane or nucleocapsid microbial proteins induce a strong immune response after nasal or parenteral administration in mice, non-human primates and humans. In addition, the immune response obtained was modulated in a Th1 sense. The VLPs were also able to immunoenhance the humoral and cellular immune responses against several viral pathogens. Studies in animals and humans with nasal and systemic formulations evidenced that it is possible to induce functional immune response against HBV, HCV, HIV and dengue virus. Invited talk at the 6th International Workshop on Advanced Materials Science and Nanotechnology, 30 October - 2 November 2012, Ha Long, Vietnam.

  14. Microlensing Binaries with Candidate Brown Dwarf Companions

    DEFF Research Database (Denmark)

    Shin, I.-G; Han, C.; Gould, A.;

    2012-01-01

    Brown dwarfs are important objects because they may provide a missing link between stars and planets, two populations that have dramatically different formation histories. In this paper, we present the candidate binaries with brown dwarf companions that are found by analyzing binary microlensing......-278/OGLE-2011-BLG-012N. Among them, we are able to confirm that the companions of the lenses of MOA-2011-BLG-104/OGLE-2011-BLG-0172 and MOA-2011-BLG-149 are brown dwarfs by determining the mass of the lens based on the simultaneous measurement of the Einstein radius and the lens parallax. The measured...... masses of the brown dwarf companions are 0.02 ± 0.01 M⊙ and 0.019 ± 0.002 M⊙ for MOA-2011-BLG-104/OGLE-2011-BLG-0172 and MOA-2011-BLG-149, respectively, and both companions are orbiting low-mass M dwarf host stars. More microlensing brown dwarfs are expected to be detected as the number of lensing events...

  15. MR imaging of cochlear implant candidates

    International Nuclear Information System (INIS)

    This paper reports on the value of diagnostic imaging in the workup of patients for possible placement of a multichannel intracochlear hearing device. Forty-five candidates for cochlear implantation were examined with both CT and MR imaging. In 32 adult patients coronal and axial T2-weighted spin-echo sequences were performed. In 10 patients, we used a T2*-weighted gradient-echo three-dimensional sequence with axial presaturation instead. Three children were examined with an ultrafast snapshot sequence for scout viewing, followed by a T2-weighted axial half-Fourier spin-echo sequence. In 36 patients we found the cochlea to be patent. Thirty-three of these patients successfully received an implant device. Three patients still await surgery. Six patients showed pathologic conditions in at least one ear at CT and MR alone. In 3 patients there was evidence of bony occulsion of the cochlear duct at CT; MR revealed a reduced signal intensity in the cochlea as well. Two patients with normal CT results showed abnormal conditions at MR imaging (reduced signal on T2-weighted images) and were not operated on

  16. ELECTIONS PENSION FUND 2nd candidate

    CERN Multimedia

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate : Name : FRANDSEN First Name : Poul Kjaer  I have been member of the staff since 1974, and member of staff council for more than 12 years, and my main motivation has been to work for improving the social conditions of the CERN staff. A very important pillar of this is a sound and healthy pension fund. A capitalised scheme has been and still is the best choice for assuring the benefits for the CERN staff, present and future, this social system being part of the whole necessary to attract the best staff to the future High Energy Physics in Europe. However, even the hypothetic close down of the Organisation should allow the benefits to exi...

  17. ELECTIONS PENSION FUND CANDIDATE NO 1

    CERN Multimedia

    2000-01-01

    This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate : Name: MAURINFirst Name:Guy I have been a member of the personnel since 1967 and as early as 1972 I was involved, in my capacity as President of the Staff Association, in the improvement of the Pension Fund benefits. As for most of us the Pension Fund is the only social provident scheme to which we belong, it is important to ensure that it is well managed and in balance. As a member of the Governing Board since 1974 and Vice-Chairman of this Board since 1977, I have continued to pursue these objectives.One of the main responsibilities of the Governing Board is our asset investment policy. The Investment Committee, of which I am Chairman, must have an overall view of the management of our 4 billion Swiss francs and seek the best yield with minimum risk. The investment structure must continuously be adapted...

  18. ELECTIONS PENSION FUND CANDIDATE NR 2

    CERN Multimedia

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate : Name : FRANDSEN First Name : Poul Kjaer  I have been member of the staff since 1974, and member of staff council for more than 12 years, and my main motivation has been to work for improving the social conditions of the CERN staff. A very important pillar of this is a sound and healthy pension fund. A capitalised scheme has been and still is the best choice for assuring the benefits for the CERN staff, present and future, this social system being part of the whole necessary to attract the best staff to the future High Energy Physics in Europe. However, even the hypothetic close down of the Organisation should allow the benefits to exi...

  19. ELECTIONS PENSION FUND CANDIDATE NO 2

    CERN Multimedia

    2000-01-01

    This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund.   Candidate: Name: RANJARDFirst Name: Florence Having been a member of the Governing Board of the Pension Fund since 1983 as Guy Maurin’s alternate, I am standing for a further 3-year term of office. Over the past few years work has concentrated essentially on following items: Monitoring of the work of the fund managers and their performances. The three-yearly study of the Fund’s actuarial situation. The pension guarantees ­ second phase. The Fund is approaching its maturity: the level of benefits exceeds contributions. In this context it has to strike a suitable balance between management of the risk from a dynamic investment policy, while a prudent policy avoiding any significant loss of its capital. These will be my concerns within the Governing Board of the Pension Fund if you...

  20. ELECTIONS PENSION FUND CANDIDATE NR 5

    CERN Multimedia

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate :  Name : Sonnemann  First Name : Florian Since my arrival at CERN in 1997 I have worked in the accelerator and administrative sectors. I have recently been elected as member of the Staff Council and of the Executive Committee of the Staff Association in which I am actively following matters concerning the Pension Fund. My candidature for the Governing Board of the CERN Pension Fund is mainly motivated to add my part in ensuring a solid financial situation of the Pension Fund. The Pension Fund is our only social security system. I wish to play a role in ensuring that the pensions will remain a secure revenue for all staff membe...

  1. ELECTIONS PENSION FUND 5th candidate

    CERN Multimedia

    2001-01-01

    ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND Caisse de Pensions - ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate :  Name : Sonnemann  First Name : Florian Since my arrival at CERN in 1997 I have worked in the accelerator and administrative sectors. I have recently been elected as member of the Staff Council and of the Executive Committee of the Staff Association in which I am actively following matters concerning the Pension Fund. My candidature for the Governing Board of the CERN Pension Fund is mainly motivated to add my part in ensuring a solid financial situation of the Pension Fund. The Pension Fund is our only social security system. I wish to play a role in ensuring that the pensions will remain a secure revenue for all staff membe...

  2. The presidential candidates on Twitter during the 2009 Romanian elections

    OpenAIRE

    Antonio MOMOC

    2012-01-01

    What changes introduced Twitter in political communication? Which are the advantages and disadvantages of Twitter usage in electoral communication for candidates and for voters? As the specialized literature barely mentions the use of Twitter in the Romanian elections, we shall answer the question regarding the way in which the 2009 presidential candidates used their own Twitter accounts. This article starts from the assumption that presidential candidates use the online communication tools i...

  3. Physical education candidate teachers' beliefs about vocational self-esteem

    OpenAIRE

    OZSAKER, Murat; CANPOLAT, A. Meliha

    2014-01-01

    The purpose of this study was to determine epistemological belief and vocational self-esteem physical education candidate teachers of Physical Education and Sports Department in 3 different universities, and also to examine effect of epistemological beliefs on vocational self-esteem. A total of 346 candidate teacher respondents (137 female and 209 male) participated in the study. Epistemological Beliefs and Vocational Self-Esteem Scale were used to determine candidate teachers’ epistemologica...

  4. Newly identified YSO candidates towards the LDN 1188

    CERN Document Server

    Marton, Gábor; Kiss, Csaba; Smidla, József

    2013-01-01

    We present an analysis of Young Stellar Object (YSO) candidates towards the LDN 1188 molecular cloud. The YSO candidates were selected from the WISE all-sky catalogue, based on a statistical method. We found 601 candidates in the region, and classified them as Class I, Flat and Class II YSOs. Groups were identified and described with the Minimal Spanning Tree (MST) method. Previously identified molecular cores show evidence of ongoing star formation at different stages throughout the cloud complex.

  5. A Catalog of Kepler Habitable Zone Exoplanet Candidates

    Science.gov (United States)

    Kane, Stephen R.; Hill, Michelle L.; Kasting, James F.; Kopparapu, Ravi Kumar; Quintana, Elisa V.; Barclay, Thomas; Batalha, Natalie M.; Borucki, William J.; Ciardi, David R.; Haghighipour, Nader; Hinkel, Natalie R.; Kaltenegger, Lisa; Selsis, Franck; Torres, Guillermo

    2016-10-01

    The NASA Kepler mission ha s discovered thousands of new planetary candidates, many of which have been confirmed through follow-up observations. A primary goal of the mission is to determine the occurrence rate of terrestrial-size planets within the Habitable Zone (HZ) of their host stars. Here we provide a list of HZ exoplanet candidates from the Kepler Q1–Q17 Data Release 24 data-vetting process. This work was undertaken as part of the Kepler HZ Working Group. We use a variety of criteria regarding HZ boundaries and planetary sizes to produce complete lists of HZ candidates, including a catalog of 104 candidates within the optimistic HZ and 20 candidates with radii less than two Earth radii within the conservative HZ. We cross-match our HZ candidates with the stellar properties and confirmed planet properties from Data Release 25 to provide robust stellar parameters and candidate dispositions. We also include false-positive probabilities recently calculated by Morton et al. for each of the candidates within our catalogs to aid in their validation. Finally, we performed dynamical analysis simulations for multi-planet systems that contain candidates with radii less than two Earth radii as a step toward validation of those systems.

  6. Extracting definition candidates from specialized corpora

    Directory of Open Access Journals (Sweden)

    Senja Pollak

    2014-07-01

    Full Text Available Human knowledge is available in different forms, including domain texts, terminological dictionaries, encyclopaediae, and recently also in computer- understandable representations of domain knowledge, such as taxonomies and ontologies. Since manual domain modeling is costly and time-consuming, researchers in human language technologies have started developing methods and tools for semi-automatic extraction of domain-specific knowledge from unstructured texts, involving tasks, such as terminology extraction, definition extraction, semantic relations extraction, or semi-automatic ontology building. This article presents a methodology for definition extraction from domain corpora, currently available for Slovene and English. Since most of the existing methods and tools are language specific and not developed for minor languages, the main contribution of the dissertation is the developed definition extraction methodology for Slovene. The proposed definition extraction methodology is based on three different approaches to extracting definition candidates. The first follows the traditional pattern-based approach, in which patterns are composed of lemmas and morphosyntactic descriptions; the second approach relies on pairs of domain terms extracted through automatic term extraction; the third approach exploits wordnet hypernym pairs. We propose an original combination of the three approaches. The developed methodology was applied to a real-case problem of modeling the language technologies domain, for which we constructed a comparable Slovene- English corpus consisting of about two million tokens. We extracted more than 3,400 definition candidates, of which over 700 (approximately 480 for Slovene and 230 for English were evaluated as definitions. The results are used as a basis for the Language Technologies Glossary.17 An additional contribution is the proposed domain-modeling pipeline—from corpus uploading and preprocessing to inspecting the

  7. Characterization for Fusion Candidate Vanadium Alloys

    Institute of Scientific and Technical Information of China (English)

    T. Muroga; T. Nagasaka; J. M. Chen; Z. Y. Xu; Q. Y. Huang; y. C. Wu

    2004-01-01

    This paper summarizes recent achievements in the characterization of candidate vanadium alloys obtained for fusion in the framework of the Japan-China Core University Program.National Institute for Fusion Science (NIFS) has a program of fabricating high-purity V-4Cr4Ti alloys. The resulting products (NIFS-HEAT-1,2), were characterized by various research groups in the world including Chinese partners. South Western Institute of Physics (SWIP) fabricated a new V-4Cr-4Ti alloy (SWIP-Heat), and carried out a comparative evaluation of hydrogen embrittlement of NIFS-HEATs and SWIP-Heat. The tensile test of hydrogen-doped alloys showed that the NIFS-HEAT maintained the ductility to relatively high hydrogen levels.The comparison of the data with those of previous studies suggested that the reduced oxygen level in the NIFS-HEATs should be responsible for the increased resistance to hydrogen embrittlement.Based on the chemical analysis data of NIFS-HEATs and SWIP-Heats, neutron-induced activation was analyzed in Institute of Plasma Physics (IPP-CAS) as a function of cooling time after the use in the fusion first wall. The results showed that the low level of Co dominates the activity up to 50 years followed by a domination of Nb or Nb and Al in the respective alloys. It was suggested that reduction of Co and Nb, both of which are thought to have been introduced via cross-contamination into the alloys from the molds used should be crucial for reducing further the activation.

  8. Corrosion resistance of candidate transportation container materials

    International Nuclear Information System (INIS)

    The Department of Energy is currently remediating several sites that have been contaminated over the years with hazardous, mixed waste and radioactive materials. Regulatory guidelines require strict compliance demonstrating public safety during remediation and the transport of these hazardous, mixed waste and radioactive materials. The compatibility of the metallic transportation containers with the contents they are designed to transport is an ultimate concern that must be satisfied to ensure public safety. The transportation issue is inherently complicated due to the complex, varied, and unknown composition of the hazardous, mixed and radioactive waste that is being, considered for transport by the DOE facilities. Never before have the interactions between the waste being transported and the materials that comprise the transportation packages been more important. Therefore, evaluation of material performance when subjected to a simulated waste will ensure that all regulatory issues and requirements for transportation of hazardous, mixed, and radioactive wastes are satisfied. The tasks encompassed by this study include defining criteria for candidate material selection, defining a test matrix that will provide pertinent information on the material compatibility with the waste stimulant, and evaluation of material performance when subjected to a stimulant waste. Our goal is to provide package design engineers with a choice of materials which exhibit enhanced performance upon exposure to hazardous, mixed, and radioactive waste that is similar in composition to the waste stimulant used in this study. Due to the fact that there are many other possible waste compositions, additional work needs to be done to broaden our materials compatibility/waste stream data base

  9. Evolution and magnitudes of candidate Planet Nine

    Science.gov (United States)

    Linder, Esther F.; Mordasini, Christoph

    2016-05-01

    Context. The recently renewed interest in a possible additional major body in the outer solar system prompted us to study the thermodynamic evolution of such an object. We assumed that it is a smaller version of Uranus and Neptune. Aims: We modeled the temporal evolution of the radius, temperature, intrinsic luminosity, and the blackbody spectrum of distant ice giant planets. The aim is also to provide estimates of the magnitudes in different bands to assess whether the object might be detectable. Methods: Simulations of the cooling and contraction were conducted for ice giants with masses of 5, 10, 20, and 50 M⊕ that are located at 280, 700, and 1120 AU from the Sun. The core composition, the fraction of H/He, the efficiency of energy transport, and the initial luminosity were varied. The atmospheric opacity was set to 1, 50, and 100 times solar metallicity. Results: We find for a nominal 10 M⊕ planet at 700 AU at the current age of the solar system an effective temperature of 47 K, much higher than the equilibrium temperature of about 10 K, a radius of 3.7 R⊕, and an intrinsic luminosity of 0.006 L♃. It has estimated apparent magnitudes of Johnson V, R, I, L, N, Q of 21.7, 21.4, 21.0, 20.1, 19.9, and 10.7, and WISE W1-W4 magnitudes of 20.1, 20.1, 18.6, and 10.2. The Q and W4 band and other observations longward of about 13 μm pick up the intrinsic flux. Conclusions: If candidate Planet 9 has a significant H/He layer and an efficient energy transport in the interior, then its luminosity is dominated by the intrinsic contribution, making it a self-luminous planet. At a likely position on its orbit near aphelion, we estimate for a mass of 5, 10, 20, and 50 M⊕ a V magnitude from the reflected light of 24.3, 23.7, 23.3, and 22.6 and a Q magnitude from the intrinsic radiation of 14.6, 11.7, 9.2, and 5.8. The latter would probably have been detected by past surveys.

  10. Elections, Information, and State-Dependent Candidate Quality

    DEFF Research Database (Denmark)

    Jensen, Thomas

    The quality of political candidates often depends on the current state of the world, for example because their personal characteristics are more valuable in some situations than in others. We explore the implications of state-dependent candidate quality in a model of electoral competition where v...

  11. 11 CFR 9033.1 - Candidate and committee agreements.

    Science.gov (United States)

    2010-01-01

    ... pursuant to 11 CFR part 9039. The candidate and authorized committee(s) shall facilitate the audit by... authorized committee(s) will comply with the conditions set forth in 11 CFR 9033.1(b). The candidate may... committee(s) will comply with the documentation requirements set forth in 11 CFR 9033.11. (3) The...

  12. Social Studies Teacher Candidates' Views on Historical Thinking Skills

    Science.gov (United States)

    Ozmen, Cengiz

    2015-01-01

    Current study aimed to present Social Studies teacher candidates' views on historical thinking skills. Study was conducted using qualitative design and working group was composed of a total of 121 teacher candidates (62 females and 59 males) attending Social Studies Teaching Department of Karadeniz Technical University and Adiyaman University…

  13. Five kepler target stars that show multiple transiting exoplanet candidates

    DEFF Research Database (Denmark)

    Steffen..[], Jason H.; Batalha, N. M.; Broucki, W J.;

    2010-01-01

    We present and discuss five candidate exoplanetary systems identified with the Kepler spacecraft. These five systems show transits from multiple exoplanet candidates. Should these objects prove to be planetary in nature, then these five systems open new opportunities for the field of exoplanets...

  14. Primary-Grade Teacher Candidates' Views on Museum Education

    Science.gov (United States)

    Tas, Ayse Mentis

    2012-01-01

    This study identifies the primary-grade teacher candidates' views on museum education. The research is a descriptive research that used survey model. The study group is made up of 209 primary-grade teacher candidates who were seniors in the Primary-Grade Teaching Program. They were all attending Konya University's Faculty of Education. A survey…

  15. Assessing Student Teaching Experiences: Teacher Candidates' Perceptions of Preparedness

    Science.gov (United States)

    Lee, Joohi; Tice, Kathleen; Collins, Denise; Brown, Amber; Smith, Cleta; Fox, Jill

    2012-01-01

    The purpose of this study is to investigate the effectiveness of student teaching experiences by measuring teacher candidates' perceptions of their preparedness. The participants were 130 teacher candidates who had completed their student teaching as part of a program preparing them to teach children in pre-K through grade 4. Teacher candidates…

  16. Chemical Literacy Levels of Science and Mathematics Teacher Candidates

    Science.gov (United States)

    Celik, Suat

    2014-01-01

    The goal of this study was to investigate Turkish science and mathematics teacher candidates' levels of attainment in chemical literacy. These candidates had all studied the new Turkish chemistry curriculum in high school. The sample of the study consisted of 112 students, who were first-year students in the Department of Secondary Science…

  17. Teacher Candidates' Views of Digital Games as Learning Devices

    Science.gov (United States)

    Sardone, Nancy B.; Devlin-Scherer, Roberta

    2009-01-01

    The objective of this research study was to explore teacher candidate views toward digital learning games using an immersive strategy. Specifically, we were interested in finding out what game use in classroom settings taught candidates about the role of teacher as facilitator of instruction. The procedures first focused teacher candidate…

  18. Investigating Academic Achievements and Critical Thinking Dispositions of Teacher Candidates

    Science.gov (United States)

    Karagöl, Ibrahim; Bekmezci, Sinan

    2015-01-01

    The aim of this study is to examine the relationship between academic achievements and critical thinking dispositions of teacher candidates in Faculty of Education and to find out whether critical thinking dispositions and academic achievements scores of teacher candidates differ according to different variables. The population consists of the…

  19. Facebook Connection Styles among Physical Education Teacher Candidates

    Science.gov (United States)

    Erdogdu, Murat

    2016-01-01

    The purpose of this study is to determine the Facebook connection styles of physical education (PE) teacher candidates. The participants were composed of 626 (age = 21.21 ± 2.024) physical education teacher candidates from the departments of Physical Education and Sports. They teach in five different universities. It was done in 2014-2015 academic…

  20. 28 CFR 105.14 - Risk assessment for candidates.

    Science.gov (United States)

    2010-07-01

    ... or national security as a result of the preliminary risk assessment, the candidate or the Provider... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Risk assessment for candidates. 105.14... CHECKS Aviation Training for Aliens and Other Designated Individuals § 105.14 Risk assessment...

  1. Preparing Preservice Teacher Candidates to Differentiate Instructional Practices

    Science.gov (United States)

    Ochoa, Bianca R.

    2013-01-01

    This action research study focused on how various grouping strategies influenced preservice teachers' differentiation of instruction. The participants included a third grade mentor teacher and three preservice teacher candidates. The candidate preparation curriculum consisted of seminars, daily field-based learning experiences, and ongoing…

  2. Opinions of Counselor Candidates Regarding Counseling Skills Training

    Science.gov (United States)

    Aladag, Mine; Yaka, Baris; Koç, Ismet

    2014-01-01

    The aim of this study is to contribute to the enhancement of the quality of counseling skills training and counselor education through the medium of understanding the opinions of counselor candidates regarding counseling skills training. The research group consisted of 67 counselor candidates who voluntarily participated in the study. The research…

  3. Developing Benchmarks to Measure Teacher Candidates' Performance

    Science.gov (United States)

    Frazier, Laura Corbin; Brown-Hobbs, Stacy; Palmer, Barbara Martin

    2013-01-01

    This paper traces the development of teacher candidate benchmarks at one liberal arts institution. Begun as a classroom assessment activity over ten years ago, the benchmarks, through collaboration with professional development school partners, now serve as a primary measure of teacher candidates' performance in the final phases of the…

  4. Fostering the Development of Chemistry Teacher Candidates: A Bioecological Approach

    Science.gov (United States)

    Lewthwaite, Brian; Wiebe, Rick

    2012-01-01

    This ongoing research inquiry investigates through the analysis of teacher candidate experiences the factors influencing two groups of chemistry teacher candidates' development during their extended practica in their second and final year of an after-degree bachelor of education at a university in central Canada. The tenets of Bronfenbrenner's…

  5. An annotated history of container candidate material selection

    International Nuclear Information System (INIS)

    This paper documents events in the Nevada Nuclear Waste Storage Investigations (NNWSI) Project that have influenced the selection of metals and alloys proposed for fabrication of waste package containers for permanent disposal of high-level nuclear waste in a repository at Yucca Mountain, Nevada. The time period from 1981 to 1988 is covered in this annotated history. The history traces the candidate materials that have been considered at different stages of site characterization planning activities. At present, six candidate materials are considered and described in the 1988 Consultation Draft of the NNWSI Site Characterization Plan (SCP). The six materials are grouped into two alloy families, copper-base materials and iron to nickel-base materials with an austenitic structure. The three austenitic candidates resulted from a 1983 survey of a longer list of candidate materials; the other three candidates resulted from a special request from DOE in 1984 to evaluate copper and copper-base alloys. 24 refs., 2 tabs

  6. PEACE: Pulsar Evaluation Algorithm for Candidate Extraction -- A software package for post-analysis processing of pulsar survey candidates

    CERN Document Server

    Lee, K J; Jenet, F A; Martinez, J; Dartez, L P; Mata, A; Lunsford, G; Cohen, S; Biwer, C M; Rohr, M; Flanigan, J; Walker, A; Banaszak, S; Allen, B; Barr, E D; Bhat, N D R; Bogdanov, S; Brazier, A; Camilo, F; Champion, D J; Chatterjee, S; Cordes, J; Crawford, F; Deneva, J; Desvignes, G; Ferdman, R D; Freire, P; Hessels, J W T; Karuppusamy, R; Kaspi, V M; Knispel, B; Kramer, M; Lazarus, P; Lynch, R; Lyne, A; McLaughlin, M; Ransom, S; Scholz, P; Siemens, X; Spitler, L; Stairs, I; Tan, M; van Leeuwen, J; Zhu, W W

    2013-01-01

    Modern radio pulsar surveys produce a large volume of prospective candidates, the majority of which are polluted by human-created radio frequency interference or other forms of noise. Typically, large numbers of candidates need to be visually inspected in order to determine if they are real pulsars. This process can be labor intensive. In this paper, we introduce an algorithm called PEACE (Pulsar Evaluation Algorithm for Candidate Extraction) which improves the efficiency of identifying pulsar signals. The algorithm ranks the candidates based on a score function. Unlike popular machine-learning based algorithms, no prior training data sets are required. This algorithm has been applied to data from several large-scale radio pulsar surveys. Using the human-based ranking results generated by students in the Arecibo Remote Command enter programme, the statistical performance of PEACE was evaluated. It was found that PEACE ranked 68% of the student-identified pulsars within the top 0.17% of sorted candidates, 95% ...

  7. A Catalog of Kepler Habitable Zone Exoplanet Candidates

    CERN Document Server

    Kane, Stephen R; Kasting, James F; Kopparapu, Ravi Kumar; Quintana, Elisa V; Barclay, Thomas; Batalha, Natalie M; Borucki, William J; Ciardi, David R; Haghighipour, Nader; Hinkel, Natalie R; Kaltenegger, Lisa; Selsis, Franck; Torres, Guillermo

    2016-01-01

    The NASA Kepler mission has discovered thousands of new planetary candidates, many of which have been confirmed through follow-up observations. A primary goal of the mission is to determine the occurrance rate of terrestrial-size planets within the Habitable Zone (HZ) of their host stars. Here we provide a list of HZ exoplanet candidates from the Kepler Data Release 24 Q1-Q17 data vetting process. This work was undertaken as part of the Kepler Habitable Zone Working Group. We use a variety of criteria regarding HZ boundaries and planetary sizes to produce complete lists of HZ candidates, including a catalog of 104 candidates within the optimistic HZ and 20 candidates with radii less than two Earth radii within the conservative HZ. We cross-match our HZ candidates with the Data Release 25 stellar properties and confirmed planet properties to provide robust stellar parameters and candidate dispositions. We also include false positive probabilities recently calculated by Morton et al. (2016) for each of the cand...

  8. Pathogenic Network Analysis Predicts Candidate Genes for Cervical Cancer

    Directory of Open Access Journals (Sweden)

    Yun-Xia Zhang

    2016-01-01

    Full Text Available Purpose. The objective of our study was to predicate candidate genes in cervical cancer (CC using a network-based strategy and to understand the pathogenic process of CC. Methods. A pathogenic network of CC was extracted based on known pathogenic genes (seed genes and differentially expressed genes (DEGs between CC and normal controls. Subsequently, cluster analysis was performed to identify the subnetworks in the pathogenic network using ClusterONE. Each gene in the pathogenic network was assigned a weight value, and then candidate genes were obtained based on the weight distribution. Eventually, pathway enrichment analysis for candidate genes was performed. Results. In this work, a total of 330 DEGs were identified between CC and normal controls. From the pathogenic network, 2 intensely connected clusters were extracted, and a total of 52 candidate genes were detected under the weight values greater than 0.10. Among these candidate genes, VIM had the highest weight value. Moreover, candidate genes MMP1, CDC45, and CAT were, respectively, enriched in pathway in cancer, cell cycle, and methane metabolism. Conclusion. Candidate pathogenic genes including MMP1, CDC45, CAT, and VIM might be involved in the pathogenesis of CC. We believe that our results can provide theoretical guidelines for future clinical application.

  9. Halo Stream candidates in the LAMOST DR2

    Science.gov (United States)

    Zhao, Jingkun

    2015-08-01

    We have detected eight stellar halo stream candidates in the solar neighborhood using a sample including 64,819 FGK metal-poor ([Fe/H] match among the LAMOST DR2, WISE, 2MASS and PPMXL catalogues. With the strategy of halo stream detection in Klement et al, several significant ‘phase-space overdensi- ties” of stars on very similar orbits are identified. Three structures are known previously. Five new halo stream candidates are also found. The kinematics and metallicity of these stream candidates are then analyzed. Detailed element abundance are needed to better know the ori-gin of these streams.

  10. Detecting candidate cosmic bubble collisions with optimal filters

    CERN Document Server

    McEwen, J D; Johnson, M C; Peiris, H V

    2012-01-01

    We review an optimal-filter-based algorithm for detecting candidate sources of unknown and differing size embedded in a stochastic background, and its application to detecting candidate cosmic bubble collision signatures in Wilkinson Microwave Anisotropy Probe (WMAP) 7-year observations. The algorithm provides an enhancement in sensitivity over previous methods by a factor of approximately two. Moreover, it is optimal in the sense that no other filter-based approach can provide a superior enhancement of these signatures. Applying this algorithm to WMAP 7-year observations, eight new candidate bubble collision signatures are detected for follow-up analysis.

  11. Planet Hunters VI: The First Kepler Seven Planet Candidate System and 13 Other Planet Candidates from the Kepler Archival Data

    CERN Document Server

    Schmitt, Joseph R; Fischer, Debra A; Jek, Kian J; Moriarty, John C; Boyajian, Tabetha S; Schwamb, Megan E; Lintott, Chris; Smith, Arfon M; Parrish, Michael; Schawinski, Kevin; Lynn, Stuart; Simpson, Robert; Omohundro, Mark; Winarski, Troy; Goodman, Samuel J; Jebson, Tony; Lacourse, Daryll

    2013-01-01

    We report the discovery of 14 new transiting planet candidates in the Kepler field from the Planet Hunters citizen science program. None of these candidates overlap with Kepler Objects of Interest (KOIs), and five of the candidates were missed by the Kepler Transit Planet Search (TPS) algorithm. The new candidates have periods ranging from 124-904 days, eight residing in their host star's habitable zone (HZ) and two (now) in multiple planet systems. We report the discovery of one more addition to the six planet candidate system around KOI-351, marking the first seven planet candidate system from Kepler. Additionally, KOI-351 bears some resemblance to our own solar system, with the inner five planets ranging from Earth to mini-Neptune radii and the outer planets being gas giants; however, this system is very compact, with all seven planet candidates orbiting $\\lesssim 1$ AU from their host star. We perform a numerical integration of the orbits and show that the system remains stable for over 100 million years....

  12. Architecture and Dynamics of Kepler's Candidate Multiple Transiting Planet Systems

    CERN Document Server

    Lissauer, Jack J; Fabrycky, Daniel C; Batalha, Natalie M; Borucki, William J; Bryson, Stephen T; Caldwell, Douglas A; Dunham, Edward W; Ford, Eric B; Fortney, Jonathan J; Gautier, Thomas N; Holman, Matthew J; Jenkins, Jon M; Koch, David G; Latham, David W; Marcy, Geoffrey W; Morehead, Robert; Rowe, Jason; Quintana, Elisa V; Sasselov, Dimitar; Shporer, Avi; Steffen, Jason H

    2011-01-01

    Borucki et al. 2011 (ApJ, submitted) report on characteristics of over 1200 candidate transiting planets orbiting nearly 1000 Kepler spacecraft target stars detected in the first four months of spacecraft data. Included among these targets are 115 targets with two transiting planet candidates, 45 targets with three, 8 with four, and one each with five and six sets of transit signatures. We characterize herein the dynamical properties of these candidate multi-planet systems. We find that virtually all systems are stable, as tested by numerical integration assuming a mass-radius relationship. The distribution of observed period ratios is also clustered just outside resonances, particularly the 2:1 resonance. Neither of these characteristics would emerge if the systems were significantly contaminated with false positives, and these combined with other considerations strongly suggest that the majority of these multi-candidate systems are true planetary systems. Using the observed multiplicity frequencies (e.g., t...

  13. Spectroscopy of candidate electromagnetic counterparts to gravitational wave sources

    CERN Document Server

    Steele, Iain A; Piascik, Andrzej S

    2016-01-01

    A programme of worldwide, multi-wavelength electromagnetic follow-up of sources detected by gravitational wave detectors is in place. Following the discovery of GW150914 and GW151226, wide field imaging of their sky localisations identified a number of candidate optical counterparts which were then spectrally classified. The majority of candidates were found to be supernovae at redshift ranges similar to the GW events and were thereby ruled out as a genuine counterpart. Other candidates ruled out include AGN and solar system objects. Given the GW sources were black hole binary mergers, the lack of an identified electromagnetic counterpart is not surprising. However the observations show that is it is possible to organise and execute a campaign that can eliminate the majority of potential counterparts. Finally we note the existence of a "classification gap" with a significant fraction of candidates going unclassified.

  14. Value-Added Measures of Teacher Candidates' Dispositions

    Science.gov (United States)

    Cosgrove, Maryellen; Carpenter, Barbara

    2012-01-01

    This article describes how a teacher preparation program can positively impact professional dispositions. Pre and post essays from a sample of sixty candidates were qualitatively analyzed to determine the value-added growth of their professional dispositions.

  15. 11 CFR 100.148 - Volunteer activity for candidate.

    Science.gov (United States)

    2010-01-01

    ..., magazines, billboards, direct mail or similar types of general public communication or political advertising... developed by the candidate. But see 11 CFR 100.24, 104.17(a), and part 300, subparts D and E for...

  16. 11 CFR 100.88 - Volunteer activity for candidates.

    Science.gov (United States)

    2010-01-01

    ..., billboards, direct mail or similar types of general public communication or political advertising. (b) The... developed by the candidate. But see 11 CFR 100.24, 104.17(a), and part 300, subparts D and E for...

  17. The impact of alternate fuels on future candidate automotive engines

    Energy Technology Data Exchange (ETDEWEB)

    Rahnke, C.J.; Nichols, R.J.

    1982-06-01

    The thermal efficiency that could occur in the future for a variety of automotive engine candidates operating on conventional and alternate fuels is projected based on current automotive engine development trends and the special characteristics of the various alternate fuels. The multi-fuel engine candidates include mixture cycle and direct injection reciprocating engines, as well as adiabatic turbocompound engines and advanced gas turbine and Stirling engines. The alternate fuels considered are propane, methanol, ethanol, diesel and methane.

  18. Transiting exoplanet candidates from K2 Campaigns 5 and 6

    Science.gov (United States)

    Pope, Benjamin J. S.; Parviainen, Hannu; Aigrain, Suzanne

    2016-10-01

    We introduce a new transit search and vetting pipeline for observations from the K2 mission, and present the candidate transiting planets identified by this pipeline out of the targets in Campaigns 5 and 6. Our pipeline uses the Gaussian process-based K2SC code to correct for the K2 pointing systematics and simultaneously model stellar variability. The systematics-corrected, variability-detrended light curves are searched for transits with the box-least-squares method, and a period-dependent detection threshold is used to generate a preliminary candidate list. Two or three individuals vet each candidate manually to produce the final candidate list, using a set of automatically generated transit fits and assorted diagnostic tests to inform the vetting. We detect 145 single-planet system candidates and 5 multi-planet systems, independently recovering the previously published hot Jupiters EPIC 212110888b, WASP-55b (EPIC 212300977b) and Qatar-2b (EPIC 212756297b). We also report the outcome of reconnaissance spectroscopy carried out for all candidates with Kepler magnitude Kp ≤ 13, identifying 12 targets as likely false positives. We compare our results to those of other K2 transit search pipelines, noting that ours performs particularly well for variable and/or active stars, but that the results are very similar overall. All the light curves and code used in the transit search and vetting process are publicly available, as are the follow-up spectra.

  19. Transiting exoplanet candidates from K2 Campaigns 5 and 6

    Science.gov (United States)

    Pope, Benjamin J. S.; Parviainen, Hannu; Aigrain, Suzanne

    2016-06-01

    We introduce a new transit search and vetting pipeline for observations from the K2 mission, and present the candidate transiting planets identified by this pipeline out of the targets in Campaigns 5 and 6. Our pipeline uses the Gaussian Process-based K2SC code to correct for the K2 pointing systematics and simultaneously model stellar variability. The systematics-corrected, variability-detrended light curves are searched for transits with the Box Least Squares method, and a period-dependent detection threshold is used to generate a preliminary candidate list. Two or three individuals vet each candidate manually to produce the final candidate list, using a set of automatically-generated transit fits and assorted diagnostic tests to inform the vetting. We detect 147 single-planet system candidates and 5 multi-planet systems, independently recovering the previously-published hot Jupiters EPIC 212110888b, WASP-55b (EPIC 212300977b) and Qatar-2b (EPIC 212756297b). We also report the outcome of reconnaissance spectroscopy carried out for all candidates with Kepler magnitude Kp ≤ 13, identifying 12 targets as likely false positives. We compare our results to those of other K2 transit search pipelines, noting that ours performs particularly well for variable and/or active stars, but that the results are very similar overall. All the light curves and code used in the transit search and vetting process are publicly available, as are the follow-up spectra.

  20. Robo-AO Kepler Planetary Candidate Survey III: Adaptive Optics Imaging of 1629 Kepler Exoplanet Candidate Host Stars

    CERN Document Server

    Ziegler, Carl; Morton, Tim; Baranec, Christoph; Riddle, Reed; Atkinson, Dani; Baker, Anna; Roberts, Sarah; Ciardi, David R

    2016-01-01

    The Robo-AO \\textit{Kepler} Planetary Candidate Survey is observing every \\textit{Kepler} planet candidate host star with laser adaptive optics imaging to search for blended nearby stars, which may be physically associated companions and/or responsible for transit false positives. We present in this paper the results of our search for stars nearby 1629 \\textit{Kepler} planet candidate hosts. With survey sensitivity to objects as close as $\\sim$0.15" and magnitude differences $\\Delta$m$\\le$6, we find 223 stars in the vicinity of 206 target KOIs; 209 of these nearby stars have not previously been imaged in high resolution. We measure an overall nearby-star probability for \\textit{Kepler} planet candidates of 12.6\\%$\\pm$0.9\\% out to a separation of 4.0". Particularly interesting KOI systems are discussed, including 23 stars with detected companions which host rocky, habitable zone candidates, and five new candidate planet-hosting quadruple star systems. We explore the broad correlations between planetary systems...

  1. Unifying candidate gene and GWAS Approaches in Asthma.

    Directory of Open Access Journals (Sweden)

    Sven Michel

    Full Text Available The first genome wide association study (GWAS for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS. We systematically identified 89 SNPs in 14 candidate genes previously associated with asthma in >3 independent study populations. We re-genotyped 39 SNPs in these genes not covered by GWAS performed in 703 asthmatics and 658 reference children. Genotyping data were compared to imputation data derived from Illumina HumanHap300 chip genotyping. Results were combined to analyze 566 SNPs covering all 14 candidate gene loci. Genotyped polymorphisms in ADAM33, GSTP1 and VDR showed effects with p-values <0.0035 (corrected for multiple testing. Combining genotyping and imputation, polymorphisms in DPP10, EDN1, IL12B, IL13, IL4, IL4R and TNF showed associations at a significance level between p = 0.05 and p = 0.0035. These data indicate that (a GWAS coverage is insufficient for many asthma candidate genes, (b imputation based on these data is reliable but incomplete, and (c SNPs in three previously identified asthma candidate genes replicate in our GWAS population with significance after correction for multiple testing in 14 genes.

  2. Transiting exoplanet candidates from K2 Campaigns 5 and 6

    CERN Document Server

    Pope, Benjamin J S; Aigrain, Suzanne

    2016-01-01

    We introduce a new transit search and vetting pipeline for observations from the K2 mission, and present the candidate transiting planets identified by this pipeline out of the targets in Campaigns 5 and 6. Our pipeline uses the Gaussian Process-based K2SC code to correct for the K2 pointing systematics and simultaneously model stellar variability. The systematics-corrected, variability-detrended light curves are searched for transits with the Box Least Squares method, and a period-dependent detection threshold is used to generate a preliminary candidate list. Two or three individuals vet each candidate manually to produce the final candidate list, using a set of automatically-generated transit fits and assorted diagnostic tests to inform the vetting. We detect 147 single-planet system candidates and 5 multi-planet systems, independently recovering the previously-published hot~Jupiters EPIC 212110888b, WASP-55b (EPIC 212300977b) and Qatar-2b (EPIC 212756297b). We also report the outcome of reconnaissance spec...

  3. Properties of Optically Selected Supernova Remnant Candidates in M33

    CERN Document Server

    Lee, Jong Hwan

    2014-01-01

    We present a sample of supernova remnant (SNR) candidates in M33 based on optical narrow band images in the Local Group Survey. We identify emission line objects that have enhanced [SII]:H{\\alpha} (> 0.4) and circular shapes using continuum-subtracted H{\\alpha}and [SII] images and produce a list of 199 SNR candidates, of which 79 are previously unknown. We classify them considering two types of criteria: their progenitor type (Type Ia and core-collapse (CC) SNRs) and their morphological type. Of the total sample, 170 are likely remnants of CC SNe and 29 are likely remnants of Type Ia SNe. We obtain a cumulative size distribution of the SNR candidates, showing that it follows a power law with an index,{\\alpha}= 2.38{\\pm}0.05 (17 < D < 50 pc). This indicates that most of the M33 SNR candidates found in this study are in the Sedov-Taylor phase, consistent with previous findings. The [SII]:H{\\alpha} distribution of the SNR candidates shows two peaks at [SII]:H{\\alpha} ~0.55 and ~0.8. Interestingly X-ray and...

  4. Integrative analysis to select cancer candidate biomarkers to targeted validation

    Science.gov (United States)

    Heberle, Henry; Domingues, Romênia R.; Granato, Daniela C.; Yokoo, Sami; Canevarolo, Rafael R.; Winck, Flavia V.; Ribeiro, Ana Carolina P.; Brandão, Thaís Bianca; Filgueiras, Paulo R.; Cruz, Karen S. P.; Barbuto, José Alexandre; Poppi, Ronei J.; Minghim, Rosane; Telles, Guilherme P.; Fonseca, Felipe Paiva; Fox, Jay W.; Santos-Silva, Alan R.; Coletta, Ricardo D.; Sherman, Nicholas E.; Paes Leme, Adriana F.

    2015-01-01

    Targeted proteomics has flourished as the method of choice for prospecting for and validating potential candidate biomarkers in many diseases. However, challenges still remain due to the lack of standardized routines that can prioritize a limited number of proteins to be further validated in human samples. To help researchers identify candidate biomarkers that best characterize their samples under study, a well-designed integrative analysis pipeline, comprising MS-based discovery, feature selection methods, clustering techniques, bioinformatic analyses and targeted approaches was performed using discovery-based proteomic data from the secretomes of three classes of human cell lines (carcinoma, melanoma and non-cancerous). Three feature selection algorithms, namely, Beta-binomial, Nearest Shrunken Centroids (NSC), and Support Vector Machine-Recursive Features Elimination (SVM-RFE), indicated a panel of 137 candidate biomarkers for carcinoma and 271 for melanoma, which were differentially abundant between the tumor classes. We further tested the strength of the pipeline in selecting candidate biomarkers by immunoblotting, human tissue microarrays, label-free targeted MS and functional experiments. In conclusion, the proposed integrative analysis was able to pre-qualify and prioritize candidate biomarkers from discovery-based proteomics to targeted MS. PMID:26540631

  5. 22 CFR 11.1 - Junior Foreign Service officer career candidate appointments.

    Science.gov (United States)

    2010-04-01

    ... affirmative factor in the selection of candidates for appointment as Foreign Service officer career candidates... political functions of the Department of State; for Career Candidates in the information/cultural...

  6. Preoperative cardiovascular investigations in liver transplant candidate: An update

    Science.gov (United States)

    Sehgal, Lalit; Srivastava, Piyush; Pandey, Chandra Kant; Jha, Amit

    2016-01-01

    Cardiovascular complications are a major cause of morbidity and mortality in patients with end-stage liver disease (ESLD) undergoing liver transplantation. Identifying candidates at the highest risk of postoperative cardiovascular complications is the cornerstone for optimizing the outcome. Ischaemic heart disease contributes to major portion of cardiovascular complications and therefore warrants evaluation in the preoperative period. Patients of ESLD usually demonstrate increased cardiac output, compromised ventricular response to stress, low systemic vascular resistance and occasionally bradycardia. Despite various recommendations for preoperative evaluation of cardiovascular disease in liver transplant candidates, a considerable controversy on screening methodology persists. This review critically focuses on the rapidly expanding body of evidence for diagnosis and risk stratification of cardiovascular disorder in liver transplant candidates. PMID:26962249

  7. Detection Confidence Tests for Burst and Inspiral Candidate Events

    CERN Document Server

    Gouaty, R

    2008-01-01

    The LIGO Scientific Collaboration (LSC) is developing and running analysis pipelines to search for gravitational-wave transients emitted by astrophysical events such as compact binary mergers or core-collapsed supernovae. However, because of the non-Gaussian, non-stationary nature of the noise exhibited by the LIGO detectors, residual false alarms might be found at the end of the pipelines. A critical aspect of the search is then to assess our confidence for gravitational waves and to distinguish them from those false alarms. Both the ''Compact Binary Coalescence'' and the ''Burst'' working groups have been developing a detection checklist for the validation of candidate-events, consisting of a series of tests including data quality checks, analysis of the candidate appearance, parameter consistency studies, coherent analysis, which aim to corroborate a detection or to eliminate a false alarm. In this paper, the general methodology used for candidate validation is presented. The method is illustrated with an ...

  8. Evaluation and selection of candidate high-level waste forms

    International Nuclear Information System (INIS)

    Seven candidate waste forms being developed under the direction of the Department of Energy's National High-Level Waste (HLW) Technology Program, were evaluated as potential media for the immobilization and geologic disposal of high-level nuclear wastes. The evaluation combined preliminary waste form evaluations conducted at DOE defense waste-sites and independent laboratories, peer review assessments, a product performance evaluation, and a processability analysis. Based on the combined results of these four inputs, two of the seven forms, borosilicate glass and a titanate based ceramic, SYNROC, were selected as the reference and alternative forms for continued development and evaluation in the National HLW Program. Both the glass and ceramic forms are viable candidates for use at each of the DOE defense waste-sites; they are also potential candidates for immobilization of commercial reprocessing wastes. This report describes the waste form screening process, and discusses each of the four major inputs considered in the selection of the two forms

  9. Former Head of CNOOC Named as Candidate for Governor

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    @@ The Central Committee of the Chinese Communist Party has appointed Wei Liucheng, Former President of CNOOC and Former Chairman and CEO of CNOOC Limited, as Deputy Secretary of Hainan Provincial Committee and named him as the candidate for Governor of Hainan Province. At a conference of Hainan Provincial Committee of the Party held on October 8, at which the organization department of the Communist Party of China announced nomination of Wei as the deputy Party secretary of Hainan, which is the second highest position in the provincial government. Wei was also chosen as a candidate for the governor of the island province.

  10. On Intrinsic Magnetic Moments In Black Hole Candidates

    CERN Document Server

    Robertson, S L; Robertson, Stanley L.; Leiter, Darryl J.

    2003-01-01

    In previous work we found that many of the spectral properties of low mass x-ray binaries, including galactic black hole candidates could be explained by a magnetic propeller model that requires an intrinsically magnetized central object. Here we describe how the Einstein field equations of General Relativity and equipartition magnetic fields permit the existence of highly red shifted, extremely long lived, collapsing, radiating objects. We examine the properties of these collapsed objects and discuss characteristics that might lead to their confirmation as the source of black hole candidate phenomena.

  11. Dark matter candidates and methods for detecting them

    Science.gov (United States)

    Raffelt, G. G.

    1992-01-01

    A number of experiments employing Ge and Si ionization detectors have excluded large regions in the plane of masses and scattering cross-sections for weakly-interacting dark matter (DM) candidates. It is judged that, before a realistic detection experiment for supersymmetric DM candidates can be conducted, significant development efforts will have to be completed for suitable cryogenic or ionization detectors. Pilot experiments have demonstrated the feasibility of axion searches with microwave cavities, but these are at least two orders of magnitude too low in sensitivity.

  12. A preliminary systems assessment of the Starlite Demo candidates

    Energy Technology Data Exchange (ETDEWEB)

    Bathke, C.G.

    1995-12-01

    The Starlite project has evaluated the following five tokamaks as candidates for the US Demo Power Plant: (1) steady state, first stability regime; (2) pulsed, first stability regime; (3) steady state, second stability regime; (4) steady state, reversed shear; and (5) steady state, low aspect ratio. Systems analysis of these candidates has played an important role in the selection of a reversed-shear tokamak for further conceptual design as a US Demo Power Plant. The cost-based systems analysis that led to the selection of a reversed-shear tokamak is described herein.

  13. Facial discrimination of political candidates and voting behavior

    Directory of Open Access Journals (Sweden)

    Alina Duduciuc

    2012-04-01

    Full Text Available After a review of psychosociological research concerning the sources of prejudices and discriminations, this article brings into discussion the cognitive approach of perceiving the other as being „otherwise” than the members of the in-group. We will discuss the situations, structural and personal factors as being some determining ones for discriminant behavior. Within the lines of cognitive paradigm, we ask how the individual does discriminate, by perceptive processes, between candidates which are considered attractive, which go together with the expectations of the electorate concerning the physical aspects and candidates who are „less desirable”.

  14. Ethical issues in the psychosocial assessment of bariatric surgery candidates.

    Science.gov (United States)

    Rouleau, Codie R; Rash, Joshua A; Mothersill, Kerry J

    2016-07-01

    Psychosocial evaluation is recommended prior to bariatric surgery. Practice guidelines have been published on assessment methods for bariatric surgery candidates, but they have not emphasized ethical issues with this population. This review outlines ethical and professional considerations for behavioral healthcare providers who conduct pre-surgical assessments of bariatric surgery candidates by merging ethical principles for mental health professionals with current practices in pre-surgical assessments. Issues discussed include the following: (a) establishing and maintaining competence, (b) obtaining informed consent, (c) respecting confidentiality, (d) avoiding bias and discrimination, (e) avoiding and addressing dual roles, (f) selecting and using psychological tests, and (g) acknowledging limitations of psychosocial assessments. PMID:25411197

  15. Kepler Mission Discovers Trove of Extrasolar Planet Candidates

    Science.gov (United States)

    Showstack, Randy

    2011-02-01

    NASA's Kepler discovery mission is collecting more than just pennies from heaven. Results from the first 4 months of science operations of the Kepler space telescope, announced on 2 February, include the discovery of 1235 candidate planets orbiting 997 stars in a small portion of the Milky Way galaxy examined by the telescope. Follow-up observations likely could confirm about 80% of the candidates as actual planets rather than false positives, according to researchers. This new trove of possible exoplanets could greatly expand the number of known planets outside of our solar system.

  16. Practical Large Scale Syntheses of New Drug Candidates

    Institute of Scientific and Technical Information of China (English)

    Hui-Yin Li

    2001-01-01

    @@ This presentation will be focus on Practical large scale syntheses of lead compounds and drug candidates from three major therapeutic areas from DuPont Pharmaceuticals Research Laboratory: 1). DMP777-a selective, non-toxic, orally active human elastase inhibitor; 2). DMP754-a potent glycoprotein IIb/IIIa antagonist; 3). R-Wafarin-the pure enantiomeric form of wafarin. The key technology used for preparation these drug candidates is asymmetric hydrogenation under very mild reaction conditions, which produced very high quality final products at large scale (>99% de, >99 A% and >99 wt%). Some practical and GMP aspects of process development will be also discussed.

  17. Practical Large Scale Syntheses of New Drug Candidates

    Institute of Scientific and Technical Information of China (English)

    Hui-Yin; Li

    2001-01-01

    This presentation will be focus on Practical large scale syntheses of lead compounds and drug candidates from three major therapeutic areas from DuPont Pharmaceuticals Research Laboratory: 1). DMP777-a selective, non-toxic, orally active human elastase inhibitor; 2). DMP754-a potent glycoprotein IIb/IIIa antagonist; 3). R-Wafarin-the pure enantiomeric form of wafarin. The key technology used for preparation these drug candidates is asymmetric hydrogenation under very mild reaction conditions, which produced very high quality final products at large scale (>99% de, >99 A% and >99 wt%). Some practical and GMP aspects of process development will be also discussed.……

  18. NEW YOUNG STAR CANDIDATES IN BRC 27 AND BRC 34

    Energy Technology Data Exchange (ETDEWEB)

    Rebull, L. M.; Laher, R.; Legassie, M. [Spitzer Science Center/Caltech, M/S 220-6, 1200 E. California Blvd., Pasadena, CA 91125 (United States); Johnson, C. H.; Carlson, S.; Clark, M.; Killingstad, N.; Koop, S. [Breck School, 123 Ottawa Avenue N., Golden Valley, MN 55422 (United States); Gibbs, J. C.; Aryal, S.; Canakapalli, T. S. [Glencoe High School, 2700 NW Glencoe Rd., Hillsboro, OR 97124 (United States); Linahan, M.; Ezyk, N.; Fagan, J. [Carmel Catholic High School, One Carmel Parkway, Mundelein, IL 60060 (United States); Sartore, D.; Badura, K. S. [Pine Ridge High School, 926 Howland Blvd., Deltona, FL 32738 (United States); Armstrong, J. D. [Las Cumbres Observatory Global Telescope (LCOGT) Network, Inc., 6740 Cortona Dr. Suite 102, Goleta, CA 93117 (United States); Allen, L. E. [National Optical Astronomy Observatory (NOAO), Tucson, AZ 85719 (United States); McGehee, P. [Infrared Processing and Analysis Center (IPAC), M/S 220-6, 1200 E. California Blvd., Pasadena, CA 91125 (United States); Padgett, D. L., E-mail: rebull@ipac.caltech.edu [NASA' s Goddard Space Flight Center (GSFC), 8800 Greenbelt Rd., Greenbelt, MD 20771 (United States); and others

    2013-01-01

    We used archival Spitzer Space Telescope mid-infrared data to search for young stellar objects (YSOs) in the immediate vicinity of two bright-rimmed clouds, BRC 27 (part of CMa R1) and BRC 34 (part of the IC 1396 complex). These regions both appear to be actively forming young stars, perhaps triggered by the proximate OB stars. In BRC 27, we find clear infrared excesses around 22 of the 26 YSOs or YSO candidates identified in the literature, and identify 16 new YSO candidates that appear to have IR excesses. In BRC 34, the one literature-identified YSO has an IR excess, and we suggest 13 new YSO candidates in this region, including a new Class I object. Considering the entire ensemble, both BRCs are likely of comparable ages, within the uncertainties of small number statistics and without spectroscopy to confirm or refute the YSO candidates. Similarly, no clear conclusions can yet be drawn about any possible age gradients that may be present across the BRCs.

  19. Candidate eco-friendly gas mixtures for MPGDs

    CERN Document Server

    AUTHOR|(CDS)2071648; Saviano, G.; Muhammad, S.; Piccolo, D.; Primavera, F.; Ferrini, M.; Parvis, M.; Grassing, S.; Colafranceschi, S.; Kjøbro, J.; Sharma, A.; Yang, D.; Chen, G.; Ban, Y.; Li, Q.

    2015-01-01

    Modern gas detectors for detection of particles require F-based gases for optimal performance. Recent regulations demand the use of environmentally unfriendly F-based gases to be limited or banned. This review studies properties of potential eco-friendly gas candidate replacements.

  20. Supporting Clinical Practice Candidates in Learning Community Development

    Science.gov (United States)

    DeJarnette, Nancy K.; Sudeck, Maria

    2015-01-01

    The purpose of this qualitative research study was to monitor pre-service teacher candidates' progression and implementation of the learning community philosophy along with classroom management strategies. The study took place during their final semester of clinical practice. Data were collected from self-reports, surveys, university supervisor…

  1. Single Transit Candidates from K2: Detection and Period Estimation

    CERN Document Server

    Osborn, H P; Brown, D J A; McCormac, J; Doyle, A P; Louden, T M; Kirk, J; Spake, J J; Lam, K W F; Walker, S R; Faedi, F; Pollacco, D L

    2015-01-01

    Photometric surveys such as Kepler have the precision to identify exoplanet and eclipsing binary candidates from only a single transit. K2, with its 75d campaign duration, is ideally suited to detect significant numbers of single-eclipsing objects. Here we develop a Bayesian transit-fitting tool ("Namaste: An Mcmc Analysis of Single Transit Exoplanets") to extract orbital information from single transit events. We achieve favourable results testing this technique on known Kepler planets, and apply the technique to 7 candidates identified from a targeted search of K2 campaigns 1, 2 and 3. We find EPIC203311200 to host an excellent exoplanet candidate with a period, assuming zero eccentricity, of $540 ^{+410}_{-230}$ days and a radius of $0.51 \\pm 0.05 R_{Jup}$. We also find six further transit candidates for which more follow-up is required to determine a planetary origin. Such a technique could be used in the future with TESS, PLATO and ground-based photometric surveys such as NGTS, potentially allowing the d...

  2. Are Teacher and Principal Candidates Prepared to Address Student Cyberbullying?

    Science.gov (United States)

    Styron, Ronald A., Jr.; Bonner, Jessica L.; Styron, Jennifer L.; Bridgeforth, James; Martin, Cecelia

    2016-01-01

    The purpose of this study was to examine the preparation of teacher and principal candidates to address problems created in K-12 settings as a result of cyberbullying. Participants included teacher and principal preparation students. Findings indicated that respondents were familiar with the most common forms of cyberbullying and its impact on…

  3. 11 CFR 110.8 - Presidential candidate expenditure limitations.

    Science.gov (United States)

    2010-01-01

    ... the aggregate of expenditures under this paragraph in any one State shall not exceed the greater of 16... CFR 110.18. (b) The expenditure limitations shall not be considered violated if, after the date of the... expenditure limitation under 11 CFR 9035.1. (d)(1) If an individual is a candidate for more than one...

  4. Evaluation of candidate geomagnetic field models for IGRF-12

    DEFF Research Database (Denmark)

    Thébault, Erwan; Finlay, Chris; Alken, Patrick;

    2015-01-01

    by the British Geological Survey (UK), DTU Space (Denmark), ISTerre (France), IZMIRAN (Russia), NOAA/NGDC (USA), GFZ Potsdam (Germany), NASA/GSFC (USA), IPGP (France), LPG Nantes (France), and ETH Zurich (Switzerland). Each candidate model was carefully evaluated and compared to all other models and a mean model...

  5. Candidate new rotavirus species in sheltered dogs, Hungary.

    Science.gov (United States)

    Mihalov-Kovács, Eszter; Gellért, Ákos; Marton, Szilvia; Farkas, Szilvia L; Fehér, Enikő; Oldal, Miklós; Jakab, Ferenc; Martella, Vito; Bányai, Krisztián

    2015-04-01

    We identified unusual rotavirus strains in fecal specimens from sheltered dogs in Hungary by viral metagenomics. The novel rotavirus species displayed limited genome sequence homology to representatives of the 8 rotavirus species, A-H, and qualifies as a candidate new rotavirus species that we tentatively named Rotavirus I. PMID:25811414

  6. First microlensing candidates from the MEGA survey of M 31

    NARCIS (Netherlands)

    de Jong, JTA; Kuijken, K; Crotts, APS; Sackett, PD; Sutherland, WJ; Uglesich, RR; Baltz, EA; Cseresnjes, P; Gyuk, G; Widrow, LM

    2004-01-01

    We present the first M 31 candidate microlensing events from the Microlensing Exploration of the Galaxy and Andromeda (MEGA) survey. MEGA uses several telescopes to detect microlensing towards the nearby Andromeda galaxy, M 3 1, in order to establish whether massive compact objects are a significant

  7. Supervising PETE Candidates Using the Situational Supervision Model

    Science.gov (United States)

    Levy, Linda S.; Johnson, Lynn V.

    2012-01-01

    Physical education teacher candidates (PETCs) often, as part of their curricular requirements, engage in early field experiences that prepare them for student teaching. Matching the PETC's developmental level with the mentor's supervision style enhances this experience. The situational supervision model, based on the situational leadership model,…

  8. Many-Objective Distinct Candidates Optimization using Differential Evolution

    DEFF Research Database (Denmark)

    Justesen, Peter; Ursem, Rasmus Kjær

    2010-01-01

    , we present the novel MODCODE algorithm incorporating the ROD measure to measure and control candidate distinctiveness. MODCODE is tested against GDE3 on three real world centrifugal pump design problems supplied by Grundfos. Our algorithm outperforms GDE3 on all problems with respect to all...

  9. Identification of candidate genes for susceptibility to reactive arthritis

    NARCIS (Netherlands)

    M. Rihl; C. Barthel; A. Klos; R.E. Schmidt; P.P. Tak; H. Zeidler; J.G. Kuipers

    2009-01-01

    This study was undertaken to evaluate the gene expression profile in monocytes from three patients with reactive arthritis (ReA) in remission in order to identify candidate genes accounting for a potential susceptibility to ReA. Gene expression analyses revealed eight differentially expressed mRNA t

  10. Effects of Critical Thinking Intervention for Early Childhood Teacher Candidates

    Science.gov (United States)

    Han, Heejeong Sophia; Brown, E. Todd

    2013-01-01

    This study is based on an intervention designed to enhance early childhood teacher candidates' critical thinking abilities. The concept, elements, standards, and traits of critical thinking were integrated into the main course contents, and the effects of the intervention were examined. The results indicated that early childhood teacher…

  11. THE 3 MU-M SPECTRA OF CANDIDATE CARBON STARS

    NARCIS (Netherlands)

    GROENEWEGEN, MAT; DEJONG, T; GEBALLE, TR

    1994-01-01

    We have searched for the 3.1 mum absorption feature, a well-known characteristic of optical carbon stars, in a sample of sixteen candidate carbon stars, most of which have very red colors and some of which have no optical counterparts. The sample was selected on the basis of similarity of LRS spectr

  12. Faculty Meeting: A Simulation for Secondary Teacher Candidates.

    Science.gov (United States)

    Hildebrand, Janet E.

    1981-01-01

    Describes a one-hour simulation used in methods courses at the University of Texas at Austin, to provide secondary teacher candidates with insights into the administrative functioning of a school and their future roles as department and school staff members. (SJL)

  13. Teacher Candidates' Attitudes to Using Oral History in History Education

    Science.gov (United States)

    Demircioglu, Ebru

    2016-01-01

    The aim of this research is to determine the views of history teacher candidates towards an oral history project carried out in the Special Teaching Method Course of the history pedagogy program of the Fatih Faculty of Education (FFE) at Karadeniz Technical University in Turkey. An open-ended questionnaire and semi-structured interview were the…

  14. Career Hints for the Doctoral Candidate Interested in Teacher Education.

    Science.gov (United States)

    Frith, Greg

    Guidelines are given to aid doctoral candidates in the selection of a specific career position within the field of teacher education. Various considerations relative to employment at differing types of universities are examined. University philosophy, monetary considerations, communication channels within the department, faculty relationships,…

  15. Candidate genes of idiopathic pulmonary fibrosis: current evidence and research

    Directory of Open Access Journals (Sweden)

    Zhou W

    2016-02-01

    Full Text Available Wei Zhou,1,2 Yaping Wang1,2 1Department of Medical Genetics, 2Jiangsu Key Laboratory of Molecular Medicine, Nanjing University School of Medicine, Nanjing, People's Republic of China Abstract: Idiopathic pulmonary fibrosis (IPF is a group of common and lethal forms of idiopathic interstitial pulmonary disease. IPF is characterized by a progressive decline in lung function with a median survival of 2–3 years after diagnosis. Although the pathogenesis of the disease remains unknown, genetic predisposition could play a causal role in IPF. A set of genes have been identified as candidate genes of IPF in the past 20 years. However, the recent technological advances that allow for the analysis of millions of polymorphisms in different subjects have deepened the understanding of the genetic complexity of IPF susceptibility. Genome-wide association studies and whole-genome sequencing continue to reveal the genetic loci associated with IPF risk. In this review, we describe candidate genes on the basis of their functions and aim to gain a better understanding of the genetic basis of IPF. The discovered candidate genes may help to clarify pivotal aspects in the diagnosis, prognosis, and therapies of IPF. Keywords: idiopathic pulmonary fibrosis, candidate genes, susceptibility 

  16. Assessment of Law Enforcement Candidates: Peer Evaluations and the MMPI.

    Science.gov (United States)

    Schumacher, Joseph E.; Scogin, Forrest

    Screening and evaluating law enforcement candidates for employment as police officers is a complex task. It has been recommended that a clinical interview and comprehensive battery of psychological tests may aid in evaluation. The Minnesota Multiphasic Personality Inventory (MMPI) is often used for this type of psychological screening. Peer…

  17. TECHNICAL BASIS FOR A CANDIDATE BUILDING MATERIALS RADIUM STANDARD

    Science.gov (United States)

    The report summarizes the technical basis for a candidate building materials radium standard. It contains the standard and a summary of the technical basis for the standard. (NOTE: The Florida Radon Research Program (FRRP), sponsored by the Environmental Protection Agency and the...

  18. Education of Doctor of Pharmacy Candidates as Mental Health Professionals.

    Science.gov (United States)

    Hayes, Peggy A.; Rosenbluth, Sidney A.

    1980-01-01

    The University of Tennessee offers an educational program to prepare Doctor of Pharmacy candidates for clinical roles in mental health care. The program consists of two core curricular elements: a didactic module and a clinical clerkship that devotes equal time to inpatient and outpatient care. Clinical guidelines and pharmacist goals are…

  19. Primary School Teacher Candidates' Geometric Habits of Mind

    Science.gov (United States)

    Köse, Nilu¨fer Y.; Tanisli, Dilek

    2014-01-01

    Geometric habits of mind are productive ways of thinking that support learning and using geometric concepts. Identifying primary school teacher candidates' geometric habits of mind is important as they affect the development of their future students' geometric thinking. Therefore, this study attempts to determine primary school…

  20. IT Service Management A guide for ITIL Foundation Exam candidates

    CERN Document Server

    Brewster, Ernest; Lawes, Aidan; Sansbury, John

    2012-01-01

    ITIL® is a framework for IT service management and provides best management practice to meet ISO/IEC 20k. This guide introduces ITIL to Foundation Exam candidates and offers a practical understanding of IT service management. The new edition is fully updated and contains several additional processes. An ITIL® licensed product.

  1. Teacher Candidates' Collaboration and Identity in Online Discussions

    Science.gov (United States)

    Bryce, Nadine

    2014-01-01

    In an online context, without facial, verbal or gestural cues, establishing identities through naming social positions appeared essential to effective written communication for graduate pre-service teacher candidates enrolled in a course on literacy education for elementary students. As they engaged in small group asynchronous discussions about…

  2. Selecting Quasar Candidates by a SVM Classification System

    CERN Document Server

    Peng, Nanbo; Zhao, Yongheng; Wu, Xuebing

    2012-01-01

    We develop and demonstrate a classification system constituted by several Support Vector Machines (SVM) classifiers, which can be applied to select quasar candidates from large sky survey projects, such as SDSS, UKIDSS, GALEX. How to construct this SVM classification system is presented in detail. When the SVM classification system works on the test set to predict quasar candidates, it acquires the efficiency of 93.21% and the completeness of 97.49%. In order to further prove the reliability and feasibility of this system, two chunks are randomly chosen to compare its performance with that of the XDQSO method used for SDSS-III's BOSS. The experimental results show that the high faction of overlap exists between the quasar candidates selected by this system and those extracted by the XDQSO technique in the dereddened i-band magnitude range between 17.75 and 22.45, especially in the interval of dereddened i-band magnitude < 20.0. In the two test areas, 57.38% and 87.15% of the quasar candidates predicted by ...

  3. Organizing a Congressional Candidate Debate as Experiential Learning

    Science.gov (United States)

    Boeckelman, Keith; Deitz, Janna L.; Hardy, Richard J.

    2008-01-01

    This article describes a political debate among congressional candidates that the authors organized in 2006. The debate was structured to maximize student involvement both in the planning stages and during the event itself. After discussing relevant literature on experiential learning, the article describes the debate format and details the issues…

  4. Operational support and analysis a guide for ITIL exam candidates

    CERN Document Server

    Sansbury, John

    2014-01-01

    This user-friendly book aims to assist candidates pass the ITIL® OSA Intermediate examination. It references material from the core ITIL texts and gives practical guidance. This new edition includes the latest ITIL guidance as well as additional insights from the author's own experience of developing effective solutions. An ITIL® licensed product.

  5. Candidate chemosensory genes in the Stemborer Sesamia nonagrioides.

    Science.gov (United States)

    Glaser, Nicolas; Gallot, Aurore; Legeai, Fabrice; Montagné, Nicolas; Poivet, Erwan; Harry, Myriam; Calatayud, Paul-André; Jacquin-Joly, Emmanuelle

    2013-01-01

    The stemborer Sesamia nonagrioides is an important pest of maize in the Mediterranean Basin. Like other moths, this noctuid uses its chemosensory system to efficiently interact with its environment. However, very little is known on the molecular mechanisms that underlie chemosensation in this species. Here, we used next-generation sequencing (454 and Illumina) on different tissues from adult and larvae, including chemosensory organs and female ovipositors, to describe the chemosensory transcriptome of S. nonagrioides and identify key molecular components of the pheromone production and detection systems. We identified a total of 68 candidate chemosensory genes in this species, including 31 candidate binding-proteins and 23 chemosensory receptors. In particular, we retrieved the three co-receptors Orco, IR25a and IR8a necessary for chemosensory receptor functioning. Focusing on the pheromonal communication system, we identified a new pheromone-binding protein in this species, four candidate pheromone receptors and 12 carboxylesterases as candidate acetate degrading enzymes. In addition, we identified enzymes putatively involved in S. nonagrioides pheromone biosynthesis, including a ∆11-desaturase and different acetyltransferases and reductases. RNAseq analyses and RT-PCR were combined to profile gene expression in different tissues. This study constitutes the first large scale description of chemosensory genes in S. nonagrioides. PMID:23781142

  6. Documenting Teacher Candidates' Professional Growth through Performance Evaluation

    Science.gov (United States)

    Brown, Elizabeth Levine; Suh, Jennifer; Parsons, Seth A.; Parker, Audra K.; Ramirez, Erin M.

    2015-01-01

    In the United States, colleges of education are responding to demands for increased accountability. The purpose of this article is to describe one teacher education program's implementation of a performance evaluation tool during final internship that measures teacher candidates' development across four domains: Planning and Preparation,…

  7. Discovery of optical candidate supernova remnants in Sagittarius

    Science.gov (United States)

    Alikakos, J.; Boumis, P.; Christopoulou, P. E.; Goudis, C. D.

    2012-08-01

    During an [O III] survey of planetary nebulae, we identified a region in Sagittarius containing several candidate supernova remants (SNRs) and obtained deep optical narrow-band images and spectra to explore their nature. We obtained images of the area of interest by acquiring observations in the emission lines of Hα + [N II], [S II] and [O III]. The resulting mosaic covers an area of 1.4° × 1.0°, where both filamentary and diffuse emission was discovered, suggesting that there is more than one SNR in the area. Deep long-slit spectra were also taken of eight different regions. Both the flux-calibrated images and the spectra show that the emission from the filamentary structures originates from shock-heated gas, while the photo-ionization mechanism is responsible for the diffuse emission. Part of the optical emission is found to be correlated with the radio at 4850 MHz suggesting that they are related, while the infrared emission found in the area at 12 μm and 22 μm marginally correlates with the optical. The presence of the [O III] emission line in one of the candidate SNRs implies that the shock velocities in the interstellar "clouds" are between 120 km s-1 and 200 km s-1, while its absence in the other candidate SNRs indicates that the shock velocities there are slower. For all candidate remnants, the [S II] λλ 6716/6731 ratio indicates that the electron densities are below 240 cm-3, while the Hα emission is measured to be between 0.6 and 41 × 10-17 erg s-1 cm-2 arcsec-2. The existence of eight pulsars within 1.5° of the center of the candidate SNRs also implies that there are many SNRs in the area as well as that the detected optical emission could be part of a number of supernovae explosions.

  8. Identification of genes from the Treacher Collins candidate region

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, M.; Dixon, J.; Edwards, S. [Univ. of California, Irvine, CA (United States)]|[Univ. of Manchester (United Kingdom)] [and others

    1994-09-01

    Treacher Collins syndrome (TCOF1) is an autosomal dominant disorder of craniofacial development. The TCOF1 locus has previously been mapped to chromosome 5q32-33. The candidate gene region has been defined as being between two flanking markers, ribosomal protein S14 (RPS14) and Annexin 6 (ANX6), by analyzing recombination events in affected individuals. It is estimated that the distance between these flanking markers is 500 kb by three separate analysis methods: (1) radiation hybrid mapping; (2) genetic linkage; and (3) YAC contig analysis. A cosmid contig which spans the candidate gene region for TCOF1 has been constructed by screening the Los Alamos National Laboratory flow-sorted chromosome 5 cosmid library. Cosmids were obtained by using a combination of probes generated from YAC end clones, Alu-PCR fragments from YACs, and asymmetric PCR fragments from both T7 and T3 cosmid ends. Exon amplifications, the selection of genomic coding sequences based upon the presence of functional splice acceptor and donor sites, was used to identify potential exon sequences. Sequences found to be conserved between species were then used to screen cDNA libraries in order to identify candidate genes. To date, four different cDNAs have been isolated from this region and are being analyzed as potential candidate genes for TCOF1. These include the genes encoding plasma glutathione peroxidase (GPX3), heparin sulfate sulfotransferase (HSST), a gene with homology to the ETS family of proteins and one which shows no homology to any known genes. Work is also in progress to identify and characterize additional cDNAs from the candidate gene region.

  9. The Important Candidate Genes in Goats - A Review

    Directory of Open Access Journals (Sweden)

    China SUPAKORN

    2009-01-01

    Full Text Available A total of 271 candidate genes have been detected in goats. However, comprehensive investigations have been carried out on the polymorphism of some genes, involved in the control of economic traits. Candidate genes have an effect on the physiological pathway, metabolism and expression of phenotypes. For growth traits, growth hormone (GH, growth hormone receptor (GHR, insulin like growth factor I (IGF-I, leptin (LEP, caprine pituitary specific transcription factor-1 (POU1F1, caprine myostatin (MSTN and bone morphogenetic protein (BMP genes are necessary for bone formation, birth weight, weaning weight, body condition and muscle growth. For reproduction, forkhead box L 2 (FOXL2, melatonin receptor 1A (MTNR1A, sex determination region of Y chromosome (SRY and amelogenin (AMEL genes influence sex determination and proliferation. The major candidate genes for milk yield and milk composition traits are the casein gene and their family. Keratin associated protein (KAP and melanocortin 1 receptor (MC1R genes are candidate genes for wool traits. The major histocompatibility complex (MHC gene is considered important for the immune system and disease resistance traits. The functions of these genes on economically important traits are different. Some genes have synergistic or antagonistic effects in nature for expression of phenotypic traits. On the other hand, some genes could control more than one trait. Also, the producers should be concerned with these effects because selection of a single trait by using only a gene could affect other traits. Therefore, the identification of candidate genes and their mutations which cause variations of gene expression and phenotype of economic traits will help breeders to search some genetic markers for these economic traits. It may be used as an aid in the selection of parent stock at an early age in the future.

  10. A Research on the Burnout and the Teaching Profession Attitudes of Teacher Candidates

    Science.gov (United States)

    Kadi, Aysegül; Beytekin, Osman Ferda; Arslan, Hasan

    2015-01-01

    Purpose of this study is to examine burnout and teaching profession attitudes of teacher candidates. Research was conducted with 287 teacher candidates. By the findings; burnout and teaching profession attitudes of teacher candidates don't differ according to their gender. Burnout of teacher candidates differs according to their graduation status…

  11. Comparing What Teacher Candidates Know about Each Other: China and the United States

    Science.gov (United States)

    Xu, Tingting; Byker, Erik Jon; Chen, Juan

    2016-01-01

    The purpose of this article is to compare teacher candidates' knowledge and perceptions about China and the United States. Using a survey research design, 91 Chinese teacher candidates and 96 teacher candidates from the United Sates participated. The survey findings indicated that, while both groups of teacher candidates had a basic level of…

  12. The CHAOS-3 Geomagnetic Field Model and Candidates for the 11th Generation IGRF

    DEFF Research Database (Denmark)

    Olsen, Nils; Mandea, Mioara; Sabaka, Terence J.;

    2010-01-01

    As a part of the 11th generation IGRF defined by IAGA, we propose a candidate model for the DGRF 2005, a candidate model for IGRF 2010 and a candidate model for the mean secular variation between 2010 and 2015. These candidate models, the derivation of which is described in the following, are bas...

  13. Robo-AO Kepler Planetary Candidate Survey II: Adaptive Optics Imaging of 969 Kepler Exoplanet Candidate Host Stars

    CERN Document Server

    Baranec, Christoph; Law, Nicholas M; Morton, Tim; Riddle, Reed; Atkinson, Dani; Schonhut, Jessica; Crepp, Justin

    2016-01-01

    We initiated the Robo-AO Kepler Planetary Candidate Survey in 2012 to observe each Kepler exoplanet candidate host star with high-angular-resolution visible-light laser-adaptive-optics imaging. Our goal is to find nearby stars lying in Kepler's photometric apertures that are responsible for the relatively high probability of false-positive exoplanet detections and that cause underestimates of the size of transit radii. Our comprehensive survey will also shed light on the effects of stellar multiplicity on exoplanet properties and will identify rare exoplanetary architectures. In this second part of our ongoing survey, we observed an additional 969 Kepler planet candidate hosts and we report blended stellar companions up to $\\Delta m \\approx 6$ that contribute to Kepler's measured light curves. We found 203 companions within $\\sim$4" of 181 of the Kepler stars, of which 141 are new discoveries. We measure the nearby-star probability for this sample of Kepler planet candidate host stars to be 10.6% $\\pm$ 1.1% a...

  14. Automatic extraction of candidate nomenclature terms using the doublet method

    Directory of Open Access Journals (Sweden)

    Berman Jules J

    2005-10-01

    Full Text Available Abstract Background New terminology continuously enters the biomedical literature. How can curators identify new terms that can be added to existing nomenclatures? The most direct method, and one that has served well, involves reading the current literature. The scholarly curator adds new terms as they are encountered. Present-day scholars are severely challenged by the enormous volume of biomedical literature. Curators of medical nomenclatures need computational assistance if they hope to keep their terminologies current. The purpose of this paper is to describe a method of rapidly extracting new, candidate terms from huge volumes of biomedical text. The resulting lists of terms can be quickly reviewed by curators and added to nomenclatures, if appropriate. The candidate term extractor uses a variation of the previously described doublet coding method. The algorithm, which operates on virtually any nomenclature, derives from the observation that most terms within a knowledge domain are composed entirely of word combinations found in other terms from the same knowledge domain. Terms can be expressed as sequences of overlapping word doublets that have more specific meaning than the individual words that compose the term. The algorithm parses through text, finding contiguous sequences of word doublets that are known to occur somewhere in the reference nomenclature. When a sequence of matching word doublets is encountered, it is compared with whole terms already included in the nomenclature. If the doublet sequence is not already in the nomenclature, it is extracted as a candidate new term. Candidate new terms can be reviewed by a curator to determine if they should be added to the nomenclature. An implementation of the algorithm is demonstrated, using a corpus of published abstracts obtained through the National Library of Medicine's PubMed query service and using "The developmental lineage classification and taxonomy of neoplasms" as a reference

  15. Frictional Behavior of Fe-based Cladding Candidates for PWR

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young-Ho; Kim, Hyung-Kyu [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Byun, Thak Sang [Oak Ridge National Lab., Oak Ridge (United States)

    2014-10-15

    After the recent nuclear disaster at Fukushima Daiichi reactors, there is a growing consensus on the development of new fuel systems (i.e., accident-tolerant fuel, ATF) that have high safety margins under design-basis accident (DBA) and beyond design-basis accident (BDBA). A common objective of various developing candidates is to archive the outstanding corrosion-resistance under severe accidents such as DBA and DBDA conditions for decreasing hydrogen production and increasing coping time to respond to severe accidents. ATF could be defined as new fuel/cladding system with enhanced accident tolerant to loss of active cooling in the core for a considerably longer time period under severe accidents while maintaining or improving the fuel performance during normal operations. This means that, in normal operating conditions, new fuel systems should be applicable to current operating PWRs for suppressing various degradation mechanisms of current fuel assembly without excessive design changes. When considering that one of the major degradation mechanisms of PWR fuel assemblies is a grid-to-rod fretting (GTRF), it is necessary to examine the tribological behavior of various ATF candidates at initial development stage. In this study, friction and reciprocating wear behavior of two kinds of Fe-based ATF candidates were examined with a reciprocating wear tests at room temperature (RT) air and water. The objective is to examine the compatibilities of these Fe-based alloys against current Zr-based alloy properties, which is used as major structural materials of PWR fuel assemblies. The reciprocating wear behaviors of Fe-based accident-tolerant fuel cladding candidates against current Zr-based alloy has been studied using a reciprocating sliding wear tester in room temperature air and water. Frictional behavior and wear depth were used for evaluating the applicability and compatibilities of Fe-based candidates without significant design changes of PWR fuel assemblies

  16. Scaling laws and universality in the choice of election candidates

    CERN Document Server

    Mantovani, M C; Moro, M V; Picoli, S; Mendes, R S

    2011-01-01

    Nowadays there is an increasing interest of physicists in finding regularities related to social phenomena. This interest is clearly motivated by applications that a statistical mechanical description of the human behavior may have in our society. By using this framework, we address this work to cover an open question related to elections: the choice of elections candidates (candidature process). Our analysis reveals that, apart from the social motivations, this system displays features of traditional out-of-equilibrium physical phenomena such as scale-free statistics and universality. Basically, we found a non-linear (power law) mean correspondence between the number of candidates and the size of the electorate (number of voters), and also that this choice has a multiplicative underlying process (lognormal behavior). The universality of our findings is supported by data from 16 elections from 5 countries. In addition, we show that aspects of network scale-free can be connected to this universal behavior.

  17. PTPS Candidate Exoplanet Host Star Radii Determination with CHARA Array

    CERN Document Server

    Zielinski, Pawel; Baines, Ellyn; Niedzielski, Andrzej; Wolszczan, Aleksander

    2012-01-01

    We propose to measure the radii of the Penn State - Torun Planet Search (PTPS) exoplanet host star candidates using the CHARA Array. Stellar radii estimated from spectroscopic analysis are usually inaccurate due to indirect nature of the method and strong evolutionary model dependency. Also the so-called degeneracy of stellar evolutionary tracks due to convergence of many tracks in the giant branch decreases the precision of such estimates. However, the radius of a star is a critical parameter for the calculation of stellar luminosity and mass, which are often not well known especially for giants. With well determined effective temperature (from spectroscopy) and radius the luminosity may be calculated precisely. In turn also stellar mass may be estimated much more precisely. Therefore, direct radii measurements increase precision in the determination of planetary candidates masses and the surface temperatures of the planets.

  18. Evaluation of candidate geomagnetic field models for IGRF-11

    DEFF Research Database (Denmark)

    Finlay, Chris; Maus, S.; Beggan, C. D.;

    2010-01-01

    ); EOST, France (team E); IPGP, France (team F); GFZ, Germany (team G) and NASA-GSFC, U.S.A. (team H). Here, we report the evaluations of candidate models carried out by the IGRF-11 task force during October/November 2009 and describe the weightings used to derive the new IGRF-11 model. The evaluations......-2005) and 2010.0 (IGRF-2010), and predictive linear secular variation for the interval 2010.0–2015.0 (SV-2010-2015) were derived from weighted averages of candidate models submitted by teams led by DTU Space, Denmark (team A); NOAA/NGDC, U.S.A. (team B); BGS, U.K. (team C); IZMIRAN, Russia (team D...

  19. On the Low False Positive Probabilities of Kepler Planet Candidates

    CERN Document Server

    Morton, Timothy D

    2011-01-01

    We present a framework to conservatively estimate the probability that any particular planet-like transit signal observed by the Kepler mission is in fact a planet, prior to any ground-based follow-up efforts. We use Monte Carlo methods based on stellar population synthesis and Galactic structure models, and we provide empirical analytic fits to our results that may be applied to the as-yet-unconfirmed Kepler candidates. We find that the false positive probability for candidates that pass preliminary Kepler vetting procedures is generally 20% to < 2%, assuming a continuous power law for the planet mass function with index alpha = -1.5. Since Kepler will detect many more planetary signals than can be positively confirmed with ground-based follow-up efforts in the near term, these calculations will be crucial to using the ensemble of Kepler data to determine population characteristic s of planetary systems.

  20. A novel live-attenuated vaccine candidate for mayaro Fever.

    Directory of Open Access Journals (Sweden)

    William J Weise

    2014-08-01

    Full Text Available Mayaro virus (MAYV is an emerging, mosquito-borne alphavirus that causes a dengue-like illness in many regions of South America, and which has the potential to urbanize. Because no specific treatment or vaccine is available for MAYV infection, we capitalized on an IRES-based approach to develop a live-attenuated MAYV vaccine candidate. Testing in infant, immunocompetent as well as interferon receptor-deficient mice demonstrated a high degree of attenuation, strong induction of neutralizing antibodies, and efficacy against lethal challenge. This vaccine strain was also unable to infect mosquito cells, a major safety feature for a live vaccine derived from a mosquito-borne virus. Further preclinical development of this vaccine candidate is warranted to protect against this important emerging disease.

  1. Identifying False Alarms in the Kepler Planet Candidate Catalog

    CERN Document Server

    Mullally, F; Thompson, Susan E; Christiansen, Jessie; Burke, Christopher; Clarke, Bruce D; Haas, Michael R

    2016-01-01

    We present a new automated method to identify instrumental features masquerading as small, long period planets in the \\kepler\\ planet candidate catalog. These systematics, mistakenly identified as planet transits, can have a strong impact on occurrence rate calculations because they cluster in a region of parameter space where Kepler's sensitivity to planets is poor. We compare individual transit-like events to a variety of models of real transits and systematic events, and use a Bayesian Information Criterion to evaluate the likelihood that each event is real. We describe our technique and test its performance on simulated data. Results from this technique are incorporated in the \\kepler\\ Q1-17 DR24 planet candidate catalog of \\citet{Coughlin15}.

  2. Current understanding of increased insulin sensitivity after exercise - emerging candidates

    DEFF Research Database (Denmark)

    Maarbjerg, Stine Just; Sylow, Lykke; Richter, Erik

    2011-01-01

    Exercise counteracts insulin resistance and improves glucose homeostasis in many ways. Apart from increasing muscle glucose uptake quickly, exercise also clearly increases muscle insulin sensitivity in the post exercise period. This review will focus on the mechanisms responsible for this increased...... signaling component in the insulin signaling pathway such as aPKC, Rac1, TBC1D4 and TBC1D1 have been described. These are all affected by both insulin and exercise which means that they are likely converging points in promoting GLUT4 translocation and therefore possible candidates for regulating insulin...... sensitivity after exercise. Whereas TBC1D1 does not appear to regulate insulin sensitivity after exercise, correlative evidence in contrast suggests TBC1D4 to be a relevant candidate. Little is known about aPKC and Rac1 in relation to insulin sensitivity after exercise. Besides mechanisms involved in...

  3. Planetary transit candidates in COROT-IRa01 field

    CERN Document Server

    Carpano, S; Alonso, R; Barge, P; Aigrain, S; Almenara, J -M; Bordé, P; Bouchy, F; Carone, L; Deeg, H J; De la Reza, R; Deleuil, M; Dvorak, R; Erikson, A; Fressin, F; Fridlund, M; Gondoin, P; Guillot, T; Hatzes, A; Jorda, L; Lammer, H; Léger, A; Llebaria, A; Magain, P; Moutou, C; Ofir, A; Ollivier, M; Pacheco, E J; Pátzold, M; Pont, F; Queloz, D; Rauer, H; Régulo, C; Renner, S; Rouan, D; Samuel, B; Schneider, J; Wuchterl, G

    2009-01-01

    Context: CoRoT is a pioneering space mission devoted to the analysis of stellar variability and the photometric detection of extrasolar planets. Aims: We present the list of planetary transit candidates detected in the first field observed by CoRoT, IRa01, the initial run toward the Galactic anticenter, which lasted for 60 days. Methods: We analysed 3898 sources in the coloured bands and 5974 in the monochromatic band. Instrumental noise and stellar variability were taken into account using detrending tools before applying various transit search algorithms. Results: Fifty sources were classified as planetary transit candidates and the most reliable 40 detections were declared targets for follow-up ground-based observations. Two of these targets have so far been confirmed as planets, COROT-1b and COROT-4b, for which a complete characterization and specific studies were performed.

  4. Short period eclipsing binary candidates identified using SuperWASP

    CERN Document Server

    Norton, A J; Evans, T; West, R G; Wheatley, P J; Anderson, D R; Barros, S C C; Butters, O W; Cameron, A Collier; Christian, D J; Enoch, B; Faedi, F; Haswell, C A; Hellier, C; Holmes, S; Horne, K D; Lister, T A; Maxted, P F L; Parley, N; Pollacco, D; Simpson, E K; Skillen, I; Smalley, B; Southworth, J; Street, R A

    2011-01-01

    We present light curves and periods of 53 candidates for short period eclipsing binary stars identified by SuperWASP. These include 48 newly identified objects with periods <2x10^4 seconds (~0.23d), as well as the shortest period binary known with main sequence components (GSC2314-0530 = 1SWASP J022050.85+332047.6) and four other previously known W UMa stars (although the previously reported periods for two of these four are shown to be incorrect). The period distribution of main sequence contact binaries shows a sharp cut-off at a lower limit of around 0.22d, but until now, very few systems were known close to this limit. These new candidates will therefore be important for understanding the evolution of low mass stars and to allow investigation of the cause of the period cut-off.

  5. Congenital diaphragmatic hernia candidate genes derived from embryonic transcriptomes

    DEFF Research Database (Denmark)

    Russell, Meaghan K; Longoni, Mauro; Wells, Julie;

    2012-01-01

    perturbations lead to CDH phenotypes, and E16.5 when the diaphragm is fully formed. Gene sets defining biologically relevant pathways and temporal expression trends were identified by using a series of bioinformatic algorithms. These developmental sets were then compared with a manually curated list of genes...... expression profiling of developing embryonic diaphragms would help identify genes likely to be associated with diaphragm defects. We generated a time series of whole-transcriptome expression profiles from laser captured embryonic mouse diaphragms at embryonic day (E)11.5 and E12.5 when experimental...... previously shown to cause diaphragm defects in humans and in mouse models. Our integrative filtering strategy identified 27 candidates for CDH. We examined the diaphragms of knockout mice for one of the candidate genes, pre-B-cell leukemia transcription factor 1 (Pbx1), and identified a range of previously...

  6. A thermodynamic approach to the affinity optimization of drug candidates.

    Science.gov (United States)

    Freire, Ernesto

    2009-11-01

    High throughput screening and other techniques commonly used to identify lead candidates for drug development usually yield compounds with binding affinities to their intended targets in the mid-micromolar range. The affinity of these molecules needs to be improved by several orders of magnitude before they become viable drug candidates. Traditionally, this task has been accomplished by establishing structure activity relationships to guide chemical modifications and improve the binding affinity of the compounds. As the binding affinity is a function of two quantities, the binding enthalpy and the binding entropy, it is evident that a more efficient optimization would be accomplished if both quantities were considered and improved simultaneously. Here, an optimization algorithm based upon enthalpic and entropic information generated by Isothermal Titration Calorimetry is presented.

  7. Candidate olfaction genes identified within the Helicoverpa armigera Antennal Transcriptome.

    Directory of Open Access Journals (Sweden)

    Yang Liu

    Full Text Available Antennal olfaction is extremely important for insect survival, mediating key behaviors such as host preference, mate choice, and oviposition site selection. Multiple antennal proteins are involved in olfactory signal transduction pathways. Of these, odorant receptors (ORs and ionotropic receptors (IRs confer specificity on olfactory sensory neuron responses. In this study, we identified the olfactory gene repertoire of the economically important agricultural pest moth, Helicoverpa armigera, by assembling the adult male and female antennal transcriptomes. Within the male and female antennal transcriptomes we identified a total of 47 OR candidate genes containing 6 pheromone receptor candidates. Additionally, 12 IR genes as well as 26 odorant-binding proteins and 12 chemosensory proteins were annotated. Our results allow a systematic functional analysis across much of conventional ORs repertoire and newly reported IRs mediating the key olfaction-mediated behaviors of H. armigera.

  8. Identifying False Alarms in the Kepler Planet Candidate Catalog

    Science.gov (United States)

    Mullally, F.; Coughlin, Jeffery L.; Thompson, Susan E.; Christiansen, Jessie; Burke, Christopher; Clarke, Bruce D.; Haas, Michael R.

    2016-07-01

    We present a new automated method to identify instrumental features masquerading as small, long-period planets in the Kepler planet candidate catalog. These systematics, mistakenly identified as planet transits, can have a strong impact on occurrence rate calculations because they cluster in a region of parameter space where Kepler’s sensitivity to planets is poor. We compare individual transit-like events to a variety of models of real transits and systematic events and use a Bayesian information criterion to evaluate the likelihood that each event is real. We describe our technique and test its performance on simulated data. Results from this technique are incorporated in the Kepler Q1–Q17 DR24 planet candidate catalog of Coughlin et al.

  9. Degradation mode surveys of high performance candidate container materials

    International Nuclear Information System (INIS)

    Corrosion resistant materials are being considered for the metallic barrier of the Yucca Mountain Project's high-level radioactive waste disposal containers. Nickel-chromium-molybdenum alloys and titanium alloys have good corrosion resistance properties and are considered good candidates for the metallic barrier. The localized corrosion phenomena, pitting and crevice corrosion, are considered as potentially limiting for the barrier lifetime. An understanding of the mechanisms of localized corrosion and of how various parameters affect it will be necessary for adequate performance assessment of candidate container materials. Examples of some of the concerns involving localized corrosion are discussed. The effects of various parameters, such as temperature and concentration of halide species, on localized corrosion are given. In addition, concerns about aging of the protective oxide layer in the expected service temperature range (50 to 250 degree C) are presented. Also some mechanistic considerations of localized corrosion are given. 45 refs., 1 tab

  10. Ground state occupation probabilities of neutrinoless double beta decay candidates

    Science.gov (United States)

    Kotila, Jenni; Barea, Jose

    2015-10-01

    A better understanding of nuclear structure can offer important constraints on the calculation of 0 νββ nuclear matrix elements. A simple way to consider differences between initial and final states of neutrinoless double beta decay candidates is to look at the ground state occupation probabilities of initial and final nuclei. As is well known, microscopic interacting boson model (IBM-2) has found to be very useful in the description of detailed aspects of nuclear structure. In this talk I will present results for ground state occupation probabilities obtained using IBM-2 for several interesting candidates of 0 νββ -decay. Comparison with recent experimental results is also made. This work was supported Academy of Finland (Project 266437) and Chilean Ministry of Education (Fondecyt Grant No. 1150564),

  11. Characteristics of Oral Abnormalities in Liver Transplant Candidates

    OpenAIRE

    Guggenheimer, J.; Close, J. M.; Eghtesad, B; Shay, C.

    2010-01-01

    Background: Several oral mucosal abnormalities have been reported to occur more frequently in patients with liver disease. It has, however, not been determined if these conditions are related to the disease or are manifestations of extraneous factors not associated with the liver pathology. Objective: To identify and quantify oral abnormalities in candidates for liver transplantation, and to determine whether these conditions were correlated with the type of liver disease or were the result o...

  12. Leadership scheme to develop the careers of talented candidates.

    Science.gov (United States)

    Lynas, Karen

    2012-02-01

    The Top Leaders programme supports career development by identifying talented staff and equipping them with a range of management skills and approaches. The programme uses a diagnostic test to help candidates assess their strengths, leadership styles and development needs, and offers them 360 degrees feedback. This enables them to identify areas they need to develop to be effective and supportive leaders. Two case studies illustrate the programme in action. PMID:22439500

  13. Predicting sensation seeking from dopamine genes: A candidate system approach

    OpenAIRE

    Derringer, Jaime; Robert F Krueger; Dick, Danielle M; Saccone, Scott; Grucza, Richard A.; Agrawal, Arpana; Lin, Peng; Almasy, Laura; Edenberg, Howard J.; Foroud, Tatiana; Nurnberger, John I.; Hesselbrock, Victor M.; Kramer, John R.; Kuperman, Samuel; Porjesz, Bernice

    2010-01-01

    Sensation seeking is a heritable personality trait that has been reliably linked to behavior disorders. The dopamine system has been hypothesized to contribute to individual differences in sensation seeking, and both experimental and observational studies in humans and non-human animals provide evidence for this relationship. We present here a candidate-system approach to genetic association analysis of sensation seeking, in which single nucleotide polymorphisms (SNPs) from a number of dopami...

  14. Genetics of osteoporosis: searching for candidate genes for bone fragility.

    Science.gov (United States)

    Rocha-Braz, Manuela G M; Ferraz-de-Souza, Bruno

    2016-08-01

    The pathogenesis of osteoporosis, a common disease with great morbidity and mortality, comprises environmental and genetic factors. As with other complex disorders, the genetic basis of osteoporosis has been difficult to identify. Nevertheless, several approaches have been undertaken in the past decades in order to identify candidate genes for bone fragility, including the study of rare monogenic syndromes with striking bone phenotypes (e.g. osteogenesis imperfecta and osteopetroses), the analysis of individuals or families with extreme osteoporotic phenotypes (e.g. idiopathic juvenile and pregnancy-related osteoporosis), and, chiefly, genome-wide association studies (GWAS) in large populations. Altogether, these efforts have greatly increased the understanding of molecular mechanisms behind bone remodelling, which has rapidly translated into the development of novel therapeutic strategies, exemplified by the tales of cathepsin K (CTSK) and sclerostin (SOST). Additional biological evidence of involvement in bone physiology still lacks for several candidate genes arisen from GWAS, opening an opportunity for the discovery of new mechanisms regulating bone strength, particularly with the advent of high-throughput genomic technologies. In this review, candidate genes for bone fragility will be presented in comprehensive tables and discussed with regard to how their association with osteoporosis emerged, highlighting key players such as LRP5, WNT1 and PLS3. Current limitations in our understanding of the genetic contribution to osteoporosis, such as yet unidentified genetic modifiers, may be overcome in the near future with better genotypic and phenotypic characterisation of large populations and the detailed study of candidate genes in informative individuals with marked phenotype. PMID:27533615

  15. Genetics of intracerebral hemorrhage: Insights from candidate gene approaches

    OpenAIRE

    Baoqiong Liu; Le Zhang; Qidong Yang

    2012-01-01

    Intracerebral hemorrhage (ICH) is a heterogeneous disease with genetic factors playing an important role. Association studies on a wide range of candidate pathways suggest a weak but significant effect for several alleles with ICH risk. Among the most widely investigated genes are those involved in the renin-angiotensin-aldosterone system (e.g., angiotensin-converting enzyme), coagulation pathway (e.g., Factor XIII, Factor VII, platelet-activating factor acetylhydrolase, Factor V Leiden, and ...

  16. Identification of new transitional disk candidates in Lupus with Herschel

    Science.gov (United States)

    Bustamante, I.; Merín, B.; Ribas, Á.; Bouy, H.; Prusti, T.; Pilbratt, G. L.; André, Ph.

    2015-06-01

    Context. New data from the Herschel Space Observatory are broadening our understanding of the physics and evolution of the outer regions of protoplanetary disks in star-forming regions. In particular they prove to be useful for identifying transitional disk candidates. Aims: The goals of this work are to complement the detections of disks and the identification of transitional disk candidates in the Lupus clouds with data from the Herschel Gould Belt Survey. Methods: We extracted photometry at 70, 100, 160, 250, 350, and 500 μm of all spectroscopically confirmed Class II members previously identified in the Lupus regions and analyzed their updated spectral energy distributions. Results: We have detected 34 young disks in Lupus in at least one Herschel band, from an initial sample of 123 known members in the observed fields. Using recently defined criteria, we have identified five transitional disk candidates in the region. Three of them are new to the literature. Their PACS-70 μm fluxes are systematically higher than those of normal T Tauri stars in the same associations, as already found in T Cha and in the transitional disks in the Chamaeleon molecular cloud. Conclusions: Herschel efficiently complements mid-infrared surveys for identifying transitional disk candidates and confirms that these objects seem to have substantially different outer disks than the T Tauri stars in the same molecular clouds. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.Tables 5-7 and Figs. 3 and 4 are available in electronic form at http://www.aanda.org

  17. Event display of a H -> 4mu candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4mu candidate event with m(4l) = 124.1 (125.1) GeV without (with) Z mass constraint. The masses of the lepton pairs are 86.3 GeV and 31.6 GeV. The event was recorded by ATLAS on 10-Jun-2012, 13:24:31 CEST in run number 204769 as event number 71902630. Zoom into the tracking detector. Muon tracks are colored red.

  18. Event display of a H -> 4mu candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4mu candidate event with m(4l) = 124.1 (125.1) GeV without (with) Z mass constraint. The masses of the lepton pairs are 86.3 GeV and 31.6 GeV. The event was recorded by ATLAS on 10-Jun-2012, 13:24:31 CEST in run number 204769 as event number 71902630. Muon tracks are colored red.

  19. Fruit and Oil Characteristics of Olive Candidate Cultivars from Turkey

    Directory of Open Access Journals (Sweden)

    Yasin OZDEMIR

    2016-06-01

    Full Text Available This is the first study in Turkey that evaluated olive fruit and oil characteristics of 23 cultivar candidates selected among 393 olive genotypes, on the bases of agronomical characteristics; the candidate cultivars were obtained by cross breeding between standard cultivars (‘Gemlik’, ‘Edinciksu’, ‘Uslu’, ‘Tavşan Yüreği’, ‘Karamürselsu’ and foreign cultivars (‘Lucques’, ‘Belle d’Espagne’ and ‘Manzanilla’. Fruit traits such as fruit weight, flesh to seed ratio, fruit and seed size, as well as oil characteristics such as moisture, oil content, specific absorption at ultraviolet light, free acid content, peroxide value, chlorophyll and fatty acid composition were determined. Fruits and oils of intensely cultivated ‘Gemlik’ and ‘Ayvalık’ olive cultivars were also analyzed to compare them with the new candidate cultivars. According to the oil content, ‘GE067’ (23.30%, ‘GE181’ (23.97%, ‘GE366’ (22.52%, ‘GE417’ (22.16%, ‘GT009’ (24.14%, ‘GT014’ (21.02%, ‘GU247’ (22.48%, ‘GU320’ (27.15% and ‘GU434’ (21.89% gave better results, thus having good potential for registration as new cultivars for oil production. ‘GE366’ and ‘GU434’ were determined as the best cultivar candidates for producing dual purpose olives (table olives and oil. ‘GE363’ had the best fatty acid composition, which is an important feature in terms of oxidative stability and disease prevention.

  20. Radium ion: A possible candidate for measuring atomic parity violation

    CERN Document Server

    Mandal, P; Mukherjee, M

    2009-01-01

    Single trapped and laser cooled Radium ion as a possible candidate for measuring the parity violation induced frequency shift has been discussed here. Even though the technique to be used is similar to that proposed by Fortson [1], Radium has its own advantages and disadvantages. The most attractive part of Radium ion as compared to that of Barium ion is its mass which comes along with added complexity of instability as well as other issues which are discussed here

  1. Association of candidate genes with antisocial drug dependence in adolescents

    OpenAIRE

    Corley, Robin P.; Zeiger, Joanna S.; Crowley, Thomas; Ehringer, Marissa A.; Hewitt, John K.; Christian J Hopfer; Lessem, Jeffrey; McQueen, Matthew B.; Rhee, Soo Hyun; Smolen, Andrew; Stallings, Michael C.; Young, Susan E.; Krauter, Kenneth

    2008-01-01

    The Colorado Center for Antisocial Drug Dependence (CADD) is using several research designs and strategies in its study of the genetic basis for antisocial drug dependence in adolescents. This study reports Single Nucleotide Polymorphism (SNP) association results from a Targeted Gene Assay (SNP chip) of 231 Caucasian male probands in treatment with antisocial drug dependence and a matched set of community controls. The SNP chip was designed to assay 1500 SNPs distributed across 50 candidate g...

  2. Three new optical nova candidates in M 31

    Science.gov (United States)

    Pietsch, W.; Henze, M.; Burwitz, V.; Kaur, A.; Hartmann, D. H.; Williams, G.; Milne, P.

    2011-06-01

    We report the discovery of three nova candidates in M 31 on 7x60s stacked R filter CCD images obtained with the robotic 60cm telescope with an E2V CCD (2kx2k, 13.5 micron sq. pixels) of the Livermore Optical Transient Imaging System (Super-LOTIS, located at Steward Observatory, Kitt Peak, Arizona, USA) on 2011 June 7.418 UT. The objects are visible on all individual images.

  3. Production and characterization of a bovine liver candidate reference material

    Science.gov (United States)

    Bianchi, S. R.; Peixoto, A. M. J.; Souza, G. B.; Tullio, R. R.; Nogueira, A. R. A.

    2016-07-01

    The preparation of a bovine liver candidate reference material and the steps are taken to confirm its homogeneity, long and short term stabilities, and consensus values are described. Details of the sample preparation and the final collaborative exercise are presented. The material elemental composition was characterized by 17 elements (As, Ca, Cd, Co, Cu, Fe, K, Mg, Mo, Mn, Na, P, Pb, Se, Sr, V, and Zn) of nutritional and toxicological significance.

  4. Women Candidates and Arab Media: Challenging Conservatism in Bahraini Politics

    OpenAIRE

    Otaibi, May Al

    2011-01-01

    Women have yet to enter to Bahrain’s parliament despite being permitted to run for some years. With its king promoting social and economic change, the media has portrayed positive images of Arab women as professionals against a backdrop of religious conservatism. The communications strategy adopted by some women candidates to attain election to parliament and the response of the local media are analysed utilizing content analysis. Despite some variation of coverage, the media in this Persian ...

  5. Investigating mathematics teacher candidates opinions about using information & communication technologies

    OpenAIRE

    Selahattin Arsan; Tamer Kutluca; İlknur Özpınar

    2011-01-01

    As it has changed all fields in our lives, technological advancements have also improved education in such a large extent that integrating technology into education is inevitable. For this reason, teachers and teacher candidates are supposed to get acquainted with technology related information and skills. This study was conducted to determine the pre-service mathematics teachers’ opinions about information and communication technologies. A questionnaire was applied to 104 mathematics teacher...

  6. Optimal selection policies for a sequence of candidate drugs

    OpenAIRE

    Charalambous, C.; Gittins, J. C.

    2008-01-01

    Pharmaceutical companies have to face huge risks and enormous costs of production before they can produce a drug. Efficient allocation of resources is essential to help in maximizing profits. Yu and Gittins (2007) described a model and associated software for determining efficient allocations for a preclinical research project. This is the starting point for this paper. We provide explicit optimal policies for the selection of successive candidate drugs for two restricted...

  7. Identification of 11 potential malaria vaccine candidates using Bioinformatics

    OpenAIRE

    Isea, Raul

    2010-01-01

    In this paper, we suggested eleven protein targets to be used as possible vaccines against Plasmodium falciparum causative agent of almost two to three million deaths per year. A comprehensive analysis of protein target have been selected from the small experimental fragment of antigen in the P. falciparum genome, all of them common to the four stages of the parasite life cycle (i.e., sporozoites, merozoites, trophozoites and gametocytes). The potential vaccine candidates should be analyzed i...

  8. The Coolest Isolated Brown Dwarf Candidate Member of TWA

    CERN Document Server

    Gagné, Jonathan; Cruz, Kelle; Lafrenière, David; Doyon, René; Malo, Lison; Artigau, Étienne

    2014-01-01

    We present two new late-type brown dwarf candidate members of the TW Hydrae association (TWA) : 2MASS J12074836-3900043 and 2MASS J12474428-3816464, which were found as part of the BANYAN all-sky survey (BASS) for brown dwarf members to nearby young associations. We obtained near-infrared (NIR) spectroscopy for both objects (NIR spectral types are respectively L1 and M9), as well as optical spectroscopy for J1207-3900 (optical spectral type is L0{\\gamma}), and show that both display clear signs of low-gravity, and thus youth. We use the BANYAN II Bayesian inference tool to show that both objects are candidate members to TWA with a very low probability of being field contaminants, although the kinematics of J1247-3816 seem slightly at odds with that of other TWA members. J1207-3900 is currently the latest-type and the only isolated L-type candidate member of TWA. Measuring the distance and radial velocity of both objects is still required to claim them as bona fide members. Such late-type objects are predicted...

  9. Examining My Assessment Literacy Instruction Practices with Teacher Candidates

    Directory of Open Access Journals (Sweden)

    Mary Rice

    2011-12-01

    Full Text Available In this self-study, the author examines her teacher education practices in preparing teacher candidates to assess the literacy of English learners (ELs. According to Lee (2007, disciplinary literary is essential to supporting students in becoming active in democratic pursuits. Conceptualizing literacy in this broader way for teacher candidates and then promoting the exclusive use of tools like fluency exercises and comprehension inventories for their classroom practice seems like a mixed message. The author identified three concepts from the course materials that she determined were important for teacher candidates to consider in assessing literacy development in ELs. These were (a notions of ELs preexisting literacy in their native languages, in particularly in content area subject matter for curriculum-making, (b fundamental understandings about second language acquisition, and (c knowledge of measurement practices as an avenue for advocacy. These three ideas framed the literature reviewed for this study and positioned the author to use narrative accounts of her teaching as data which yielded findings.

  10. Candidate z~8-9 Galaxies from WFC3 Imaging

    CERN Document Server

    Lorenzoni, Silvio; Wilkins, Stephen; Stanway, Elizabeth; Jarvis, Matt; Caruana, Joseph

    2010-01-01

    We present a search for galaxies at 7.5candidates at redshift z~8-9 over an area of ~50 square arcminutes. Previous searches for Y-drops with WFC3 have focussed only on the Hubble Ultra Deep Field (HUDF), and our larger survey (involving two other nearby deep fields and a wider area survey) has trebelled the number of robust Y-drop candidates. For the first time, we have sufficient Z~8-9 galaxies to fit a both phi* and M* of the UV Schechter luminosity function. There is evidence for evolution in this luminosity function from z=6-7 to z=8-9, in the sense that there are fewer UV-bright galaxies at z~8-9, consistent with an evolution mainly in M*. The candidate z~8-9 galaxies we detect have insufficient ionizing flux to ...

  11. TIME SERIES FORECASTING WITH MULTIPLE CANDIDATE MODELS: SELECTING OR COMBINING?

    Institute of Scientific and Technical Information of China (English)

    YU Lean; WANG Shouyang; K. K. Lai; Y.Nakamori

    2005-01-01

    Various mathematical models have been commonly used in time series analysis and forecasting. In these processes, academic researchers and business practitioners often come up against two important problems. One is whether to select an appropriate modeling approach for prediction purposes or to combine these different individual approaches into a single forecast for the different/dissimilar modeling approaches. Another is whether to select the best candidate model for forecasting or to mix the various candidate models with different parameters into a new forecast for the same/similar modeling approaches. In this study, we propose a set of computational procedures to solve the above two issues via two judgmental criteria. Meanwhile, in view of the problems presented in the literature, a novel modeling technique is also proposed to overcome the drawbacks of existing combined forecasting methods. To verify the efficiency and reliability of the proposed procedure and modeling technique, the simulations and real data examples are conducted in this study.The results obtained reveal that the proposed procedure and modeling technique can be used as a feasible solution for time series forecasting with multiple candidate models.

  12. THE EVALUATION OF THE MOTIVATIONS OF TEACHER CANDIDATES

    Directory of Open Access Journals (Sweden)

    Zuhal ÇELİKTÜRK

    2013-06-01

    Full Text Available The aim in this study is to define the reading profiles of teacher candidates in terms of text/reading types and reading purposes. The study is designed as a screening type, qualitative research. 65 teacher candidates from Mehmet Akif Ersoy University are selected with random sampling to take place in the study. The data is collected by the interview method, which is a qualitative research method. An interview form named “Motivation to Read Profile”, that is adapted by researchers, is used as the tool for data collection. Data is analyzed by content analyzing. At the end of the study it’s determined that, 80% of the teacher candidates have high motivations to read; and they usually read to acquire information, get the help of their teachers ad friends to choose books, use internet a lot for finding reading materials, and they don’t usually carry books with themselves, yet they read at home and library. Also, the results show that the readings at home are usually news/newspapers on the internet, and the readings at library are more generally for research and homework; because of this, readings at library are more focused on books and magazines.

  13. Evaluation and selection of candidate high-level waste forms

    Energy Technology Data Exchange (ETDEWEB)

    Bernadzikowski, T. A.; Allender, J. S.; Butler, J. L.; Gordon, D. E.; Gould, Jr., T. H.; Stone, J. A.

    1982-03-01

    Seven candidate waste forms being developed under the direction of the Department of Energy's National High-Level Waste (HLW) Technology Program, were evaluated as potential media for the immobilization and geologic disposal of high-level nuclear wastes. The evaluation combined preliminary waste form evaluations conducted at DOE defense waste-sites and independent laboratories, peer review assessments, a product performance evaluation, and a processability analysis. Based on the combined results of these four inputs, two of the seven forms, borosilicate glass and a titanate based ceramic, SYNROC, were selected as the reference and alternative forms for continued development and evaluation in the National HLW Program. Both the glass and ceramic forms are viable candidates for use at each of the DOE defense waste-sites; they are also potential candidates for immobilization of commercial reprocessing wastes. This report describes the waste form screening process, and discusses each of the four major inputs considered in the selection of the two forms.

  14. Five Kepler Target Stars That Show Multiple Transiting Exoplanet Candidates

    Science.gov (United States)

    Steffen, Jason H.; Batalha, Natalie M.; Borucki, William J.; Buchhave, Lars A.; Caldwell, Douglas A.; Cochran, William D.; Endl, Michael; Fabrycky, Daniel C.; Fressin, François; Ford, Eric B.; Fortney, Jonathan J.; Haas, Michael J.; Holman, Matthew J.; Howell, Steve B.; Isaacson, Howard; Jenkins, Jon M.; Koch, David; Latham, David W.; Lissauer, Jack J.; Moorhead, Althea V.; Morehead, Robert C.; Marcy, Geoffrey; MacQueen, Phillip J.; Quinn, Samuel N.; Ragozzine, Darin; Rowe, Jason F.; Sasselov, Dimitar D.; Seager, Sara; Torres, Guillermo; Welsh, William F.

    2010-12-01

    We present and discuss five candidate exoplanetary systems identified with the Kepler spacecraft. These five systems show transits from multiple exoplanet candidates. Should these objects prove to be planetary in nature, then these five systems open new opportunities for the field of exoplanets and provide new insights into the formation and dynamical evolution of planetary systems. We discuss the methods used to identify multiple transiting objects from the Kepler photometry as well as the false-positive rejection methods that have been applied to these data. One system shows transits from three distinct objects while the remaining four systems show transits from two objects. Three systems have planet candidates that are near mean motion commensurabilities—two near 2:1 and one just outside 5:2. We discuss the implications that multi-transiting systems have on the distribution of orbital inclinations in planetary systems, and hence their dynamical histories, as well as their likely masses and chemical compositions. A Monte Carlo study indicates that, with additional data, most of these systems should exhibit detectable transit timing variations (TTVs) due to gravitational interactions, though none are apparent in these data. We also discuss new challenges that arise in TTV analyses due to the presence of more than two planets in a system.

  15. Identification of candidate genes for dyslexia susceptibility on chromosome 18.

    Directory of Open Access Journals (Sweden)

    Thomas S Scerri

    Full Text Available Six independent studies have identified linkage to chromosome 18 for developmental dyslexia or general reading ability. Until now, no candidate genes have been identified to explain this linkage. Here, we set out to identify the gene(s conferring susceptibility by a two stage strategy of linkage and association analysis.Linkage analysis: 264 UK families and 155 US families each containing at least one child diagnosed with dyslexia were genotyped with a dense set of microsatellite markers on chromosome 18. Association analysis: Using a discovery sample of 187 UK families, nearly 3000 SNPs were genotyped across the chromosome 18 dyslexia susceptibility candidate region. Following association analysis, the top ranking SNPs were then genotyped in the remaining samples. The linkage analysis revealed a broad signal that spans approximately 40 Mb from 18p11.2 to 18q12.2. Following the association analysis and subsequent replication attempts, we observed consistent association with the same SNPs in three genes; melanocortin 5 receptor (MC5R, dymeclin (DYM and neural precursor cell expressed, developmentally down-regulated 4-like (NEDD4L.Along with already published biological evidence, MC5R, DYM and NEDD4L make attractive candidates for dyslexia susceptibility genes. However, further replication and functional studies are still required.

  16. Universal behaviors as candidate traditions in wild spider monkeys.

    Directory of Open Access Journals (Sweden)

    Claire J Santorelli

    Full Text Available Candidate traditions were documented across three communities of wild spider monkeys (Ateles geoffroyi using an a priori approach to identify behavioral variants and a statistical approach to examine differences in their proportional use. This methodology differs from previous studies of animal traditions, which used retrospective data and relied on the 'exclusion method' to identify candidate traditions. Our a priori approach increased the likelihood that behavior variants with equivalent functions were considered and our statistical approach enabled the proportional use of 'universal' behaviors, i.e., used across all communities, to be examined for the first time in any animal species as candidate traditions. Among universal behaviors we found 14 'community preferred' variants. After considering the extent to which community preferred variants were due to ecological and, to a lesser degree, genetic differences, we concluded that at least six were likely maintained through social learning. Our findings have two main implications: (i tradition repertoires could be larger than assumed from previous studies using the exclusion method; (ii the relative use of universal behavior variants can reinforce community membership.

  17. Searches for millisecond pulsar candidates among the unidentified Fermi objects

    CERN Document Server

    Hui, C Y; Hu, C P; Lin, L C C; Li, K L; Kong, A K H; Tam, P H T; Takata, J; Cheng, K S; Jin, Ruolan; Yen, T -C; Kim, Chunglee

    2015-01-01

    Here we report the results of searching millisecond pulsar (MSP) candidates from the Fermi LAT second source catalog (2FGL). Seven unassociated $\\gamma-$ray sources in this catalog are identified as promising MSP candidates based on their $\\gamma$-ray properties. Through the X-ray analysis, we have detected possible X-ray counterparts, localized to an arcsecond accuracy. We have systematically estimated their X-ray fluxes and compared with the corresponding $\\gamma$-ray fluxes. The X-ray to $\\gamma$-ray flux ratios for 2FGL J1653.6-0159 and 2FGL J1946.4-5402 are comparable with the typical value for pulsars. For 2FGL J1625.2-0020, 2FGL J1653.6-0159 and 2FGL J1946.4-5402, their candidate X-ray counterparts are bright enough for performing a detailed spectral and temporal analysis to discriminate their thermal/non thermal nature and search for the periodic signal. We have also searched for possible optical/IR counterparts at the X-ray positions. For the optical/IR source coincident with the brightest X-ray obje...

  18. Five Kepler target stars that show multiple transiting exoplanet candidates

    Energy Technology Data Exchange (ETDEWEB)

    Steffen, Jason H.; /Fermilab; Batalha, Natalie M.; /San Jose State U.; Borucki, William J.; /NASA, Ames; Buchhave, Lars A.; /Harvard-Smithsonian Ctr. Astrophys. /Bohr Inst.; Caldwell, Douglas A.; /NASA, Ames /SETI Inst., Mtn. View; Cochran, William D.; /Texas U.; Endl, Michael; /Texas U.; Fabrycky, Daniel C.; /Harvard-Smithsonian Ctr. Astrophys.; Fressin, Francois; /Harvard-Smithsonian Ctr. Astrophys.; Ford, Eric B.; /Florida U.; Fortney, Jonathan J.; /UC, Santa Cruz, Phys. Dept. /NASA, Ames

    2010-06-01

    We present and discuss five candidate exoplanetary systems identified with the Kepler spacecraft. These five systems show transits from multiple exoplanet candidates. Should these objects prove to be planetary in nature, then these five systems open new opportunities for the field of exoplanets and provide new insights into the formation and dynamical evolution of planetary systems. We discuss the methods used to identify multiple transiting objects from the Kepler photometry as well as the false-positive rejection methods that have been applied to these data. One system shows transits from three distinct objects while the remaining four systems show transits from two objects. Three systems have planet candidates that are near mean motion commensurabilities - two near 2:1 and one just outside 5:2. We discuss the implications that multitransiting systems have on the distribution of orbital inclinations in planetary systems, and hence their dynamical histories; as well as their likely masses and chemical compositions. A Monte Carlo study indicates that, with additional data, most of these systems should exhibit detectable transit timing variations (TTV) due to gravitational interactions - though none are apparent in these data. We also discuss new challenges that arise in TTV analyses due to the presence of more than two planets in a system.

  19. First microlensing candidate towards M31 from Nainital Microlensing Survey

    CERN Document Server

    Joshi, Y C; Narasimha, D; Sagar, R

    2004-01-01

    We report our first microlensing candidate NMS-E1 towards M31 from the data accumulated during four years long Nainital Microlensing Survey. Cousin R and I band observations of ~13'x13' field in the direction of M31 were carried out since 1998 and data is analysed using pixel technique proposed by the AGAPE collaboration. The NMS-E1 lies in the disk of M31 at \\alpha = 0:43:33.3 and \\delta = +41:06:44, about 15.5 arcmin away in the South-East direction from the center of M31. The degenerate Paczy\\'{n}ski fit gives a half intensity duration of ~ 59 days. The photometric analysis of candidate shows that it reached up to R ~ 20.1 mag at the time of maximum brightness and colour of the source star estimated to be (R-I)_0 ~ 1.1 mag. It is seen that the microlensing candidate is blended by red variable stars consequently light curves do not strictly follow the characteristic Paczy\\'{n}ski shape and achromatic nature however its long period monitoring and similar behaviour in R and I bands lend support of its microle...

  20. Identification of new transitional disk candidates in Lupus with Herschel

    CERN Document Server

    Bustamante, I; Ribas, Á; Bouy, H; Prusti, T; Pilbratt, G L; André, Ph

    2015-01-01

    New data from the Herschel Space Observatory are broadening our understanding of the physics and evolution of the outer regions of protoplanetary disks in star forming regions. In particular they prove to be useful to identify transitional disk candidates. The goals of this work are to complement the detections of disks and the identification of transitional disk candidates in the Lupus clouds with data from the Herschel Gould Belt Survey. We extracted photometry at 70, 100, 160, 250, 350 and 500 $\\mu$m of all spectroscopically confirmed Class II members previously identified in the Lupus regions and analyzed their updated spectral energy distributions. We have detected 34 young disks in Lupus in at least one Herschel band, from an initial sample of 123 known members in the observed fields. Using the criteria defined in Ribas et al. (2013) we have identified five transitional disk candidates in the region. Three of them are new to the literature. Their PACS-70 $\\mu$m fluxes are systematically higher than thos...

  1. Blazar candidates beyond redshift 4 observed by Swift

    CERN Document Server

    Sbarrato, T; Tagliaferri, G; Foschini, L; Nardini, M; Tavecchio, F; Gehrels, N

    2014-01-01

    We have selected SDSS J222032.50+002537.5 and SDSS J142048.01+120545.9 as best blazar candidates out of a complete sample of extremely radio-loud quasars at z>4, with highly massive black holes. We observed them and a third serendipitous candidate with similar features (PMN J2134-0419) in the X-rays with the Swift/XRT telescope, to confirm their blazar nature. We observed strong and hard X-ray fluxes in all three cases. This allowed us to classify our candidates as real blazars, being characterized by large Lorentz factors (~13) and very small viewing angles (~3deg). All three sources have black hole masses exceeding 10^9Msun and their classification provides intriguing constraints on supermassive black hole formation and evolution models. We confirm our earlier suggestion that there are different formation epochs of extremely massive black holes hosted in jetted (z~4) and non-jetted systems (z~2.5).

  2. Pulmonary Rehabilitation in Lung Transplant Candidates: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Stefanie Tonguino Rosero

    2013-09-01

    Full Text Available Pulmonary rehabilitation (PR aims to improve physical fitness and to decrease symptoms in patients with chronic lung disease; however there is not clear evidence regarding the benefits of PR in candidates for lung transplantation (LT. Objective. To determine the effectiveness of PR in LT candidates and also to find out how quality of life and exercise tolerance affects the survival of these patients. Methodology. Electronic databases (Medline, Cochrane, PEDro, Scient Direct and SciELO Search of articles in spanish, english or portuguese; controlled clinical trials and cohort studies published between 2000-2011 regarding PR in candidates for LT, the model of Cochrane systematic reviews was used. Results. The papers included were four cohort, two of which regarded of survival pre LT using the six minutes walking test (6MWT; a study of quality of life related to post LT survival and an exercise tolerance study. Controlled clinical trial was not found. Conclusions. The information found in the included studies had clinical and methodological heterogeneity therefore a meta-analysis could not been undertaken. The PR should be considered as an essential part to maintain the exercise tolerance and the patient’s survival. Research regarding this subject is important and should be carried out.

  3. NHI economic analysis of candidate nuclear hydrogen processes

    International Nuclear Information System (INIS)

    The DOE Nuclear Hydrogen Initiative (NHI) is investigating candidate technologies for large scale hydrogen production using high temperature gas-cooled reactors (HTGR) in concert with the Next Generation Nuclear Plant (NGNP) programme. The candidate processes include high temperature thermochemical and high temperature electrolytic processes which are being investigated in a sequence of experimental and analytic studies to establish the most promising and cost effective means of hydrogen production with nuclear energy. Although these advanced processes are in an early development stage, it is important that the projected economic potential of these processes be evaluated to assist in the prioritisation of research activities, and ultimately in the selection of the most promising processes for demonstration and deployment. The projected cost of hydrogen produced is the most comprehensive metric in comparing candidate processes. Since these advanced processes are in the early stages of development and much of the technology is still unproven, the estimated production costs are also significantly uncertain. The programme approach has been to estimate the cost of hydrogen production from each process periodically, based on the best available data at that time, with the intent of increasing fidelity and reducing uncertainty as the research programme and system definition studies progress. These updated cost estimates establish comparative costs at that stage of development but are also used as inputs to the evaluation of research priorities, and identify the key cost and risk (uncertainty) drivers for each process. The economic methodology used to assess the candidate processes are based on the H2A ground rules and modelling tool (discounted cash flow) developed by the DOE Office of Energy Efficiency and Renewable Energy (EERE). The figure of merit output from the calculation is the necessary selling price for hydrogen in dollars per kilogram that satisfies the cost

  4. Transiting planet candidates with ASTEP 400 at Dome C, Antarctica

    Science.gov (United States)

    Mékarnia, D.; Guillot, T.; Rivet, J.-P.; Schmider, F.-X.; Abe, L.; Gonçalves, I.; Agabi, A.; Crouzet, N.; Fruth, T.; Barbieri, M.; Bayliss, D. D. R.; Zhou, G.; Aristidi, E.; Szulagyi, J.; Daban, J.-B.; Fanteï-Caujolle, Y.; Gouvret, C.; Erikson, A.; Rauer, H.; Bouchy, F.; Gerakis, J.; Bouchez, G.

    2016-08-01

    ASTEP 400, the main instrument of the ASTEP (Antarctica Search for Transiting ExoPlanets) programme, is a 40-cm telescope, designed to withstand the harsh conditions in Antarctica, achieving a photometric accuracy of a fraction of milli-magnitude on hourly timescales for planet-hosting southern bright (R˜12 mag) stars. We review the performances of this instrument, describe its operating conditions, and present results from the analysis of observations obtained during its first three years (2010-2012) of operation, before its repatriation in 2014. During this time, we observed a total of 22 stellar fields (1° × 1° FoV). Each field, in which we measured stars up to magnitude R=18 mag, was observed continuously during ˜7 to ˜30 days. More than 200 000 frames were recorded and 310 000 stars processed, using an implementation of the optimal image subtraction (OIS) photometry algorithm. We found 43 planetary transit candidates. Twenty of these candidates were observed using spectroscopic follow-ups including four targets classified as good planet candidates. Our results demonstrate that accurate near-continuous photometric observations are achievable from the Concordia station at Dome C in Antarctica, even if we were not able to reach the nominal photometric precision of the instrument. We conducted a correlation analysis between the RMS noise and a large number of external parameters and found that source of the ˜1 mmag correlated noise is not obvious and does not depend on a single parameter. However, our analysis provided some hints and guidance to increase the photometric accuracy of the instrument. These improvements should equip any future telescope operating in Antarctica.

  5. Recruiting qualified home care aides: new candidate pools.

    Science.gov (United States)

    Wilner, M A

    1999-04-01

    With the demographic surge of baby boomers and the number of women aged 25-45 projected to decline, the coming decades will see a shortage of workers to care for the elderly. Home care aide agencies will only be able to retain their competitive edge if they widen the pool of candidates from which they recruit and create an attractive and decent job. Creating a decent job with adequate pay, benefits, and support is a business strategy that will attract a wider range of workers, including those with minimal experience, and have positive ramifications for health care in the future--and now. PMID:10537510

  6. Thermodynamic analysis of a kagome spin liquid candidate

    Science.gov (United States)

    Han, Tianheng; Bonnoit, Craig; Chisnell, Robin; Helton, Joel; Takano, Yasu; Lee, Young

    2013-03-01

    Herbertsmithite ZnCu3(OH)6Cl2-one of the most promising quantum spin liquid candidates-presents a promising system for studies of frustrated magnetism on an S =1/2 kagomé lattice. Following our recent success in crystal growth, specific heat has been measured at dilution fridge temperatures up to 18 T on a single crystal sample which gives further information on the low temperature phase. Additional analysis of the thermodynamic measurements on single crystal samples lends further hints on the intrinsic spin liquid physics.

  7. Tetravalent DNA vaccine product as a vaccine candidate against dengue.

    Science.gov (United States)

    Porter, Kevin R; Teneza-Mora, Nimfa; Raviprakash, Kanakatte

    2014-01-01

    Dengue is the most important arbovirus worldwide and is the virus that causes dengue fever and the more severe dengue hemorrhagic fever. There are four serotypes of dengue with each possessing the ability to cause disease. Developing a preventive vaccine is the most efficient and effective way to prevent these diseases, and because immunity to one serotype does not protect against the other serotypes, a vaccine must provide tetravalent protection. We used DNA immunization as a platform to develop a tetravalent vaccine. In this chapter, we describe the laboratory, regulatory, and clinical methodology for evaluating a candidate tetravalent vaccine in a Phase 1 clinical trial. PMID:24715294

  8. ASSESSING THE FUTURE MIGRATION POTENTIAL OF THE EU CANDIDATE COUNTRIES

    OpenAIRE

    Assoc. Prof. Ph.D Vesna Bucevska

    2010-01-01

    In the realm of the EU accession, the EU candidate countries and EU are facing a number of challenges raised by the potential migration from these countries to EU. In this paper we try to answer the question if the fear of large migration pressure from these countries to EU is justified by estimating the migration potential of Croatia, Macedonia and Turkey to Germany, as the most dominant EU receiving country of immigrants in the period 1997-2007. The results from the extended gravity model r...

  9. Assessment of potential solder candidates for high temperature applications

    DEFF Research Database (Denmark)

    of the package with different solders of different melting temperatures. High Pb containing alloys where the lead levels can be above 85% by weight, is one of the solders currently being used in this technology. Responding to market pressure i.e. need for green electronic products there is now an increasing...... complicates the corrosion problems. Although the cost of corrosion in the electronic sector could not be estimated, it has been suggested that a significant part of all electronic system failures are caused by corrosion. Thus, the determined potential solder candidates were classified based on its property...

  10. Event display of a H -> 4e candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4e candidate event with m(4l) = 124.5 (124.6) GeV without (with) Z mass constraint. The masses of the lepton pairs are 70.6 GeV and 44.7 GeV. The event was recorded by ATLAS on 18-May-2012, 20:28:11 CEST in run number 203602 as event number 82614360. Zoom into the tracking detector and the LAr calorimeter where its detailed structure is highlighted. The tracks and clusters of the two electron pairs are colored red and blue, respectively.

  11. Event display of a H -> 4e candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4e candidate event with m(4l) = 124.5 (124.6) GeV without (with) Z mass constraint. The masses of the lepton pairs are 70.6 GeV and 44.7 GeV. The event was recorded by ATLAS on 18-May-2012, 20:28:11 CEST in run number 203602 as event number 82614360. The tracks and clusters of the two electron pairs are colored red and blue, respectively.

  12. Event display of a H -> 4e candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4e candidate event with m(4l) = 124.5 (124.6) GeV without (with) Z mass constraint. The masses of the lepton pairs are 70.6 GeV and 44.7 GeV. The event was recorded by ATLAS on 18-May-2012, 20:28:11 CEST in run number 203602 as event number 82614360. Zoom into the tracking detector. The tracks and clusters of the two electron pairs are colored red and blue, respectively.

  13. Event display of a H -> 4e candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4e candidate event with m(4l) = 124.5 (124.6) GeV without (with) Z mass constraint. The masses of the lepton pairs are 70.6 GeV and 44.7 GeV. The event was recorded by ATLAS on 18-May-2012, 20:28:11 CEST in run number 203602 as event number 82614360. The tracks of the two electron pairs are colored red, the clusters in the LAr calorimeter are colored darkgreen.

  14. The rhesus monkey (Macaca mulatta) as a flight candidate

    Science.gov (United States)

    Debourne, M. N. G.; Bourne, G. H.; Mcclure, H. M.

    1977-01-01

    The intelligence and ruggedness of rhesus monkeys, as well as the abundance of normative data on their anatomy, physiology, and biochemistry, and the availability of captive bred animals qualify them for selection as candidates for orbital flight and weightlessness studies. Baseline data discussed include: physical characteristics, auditory thresholds, visual accuity, blood, serological taxomony, immunogenetics, cytogenics, circadian rhythms, respiration, cardiovascular values, corticosteroid response to charr restraint, microscopy of tissues, pathology, nutrition, and learning skills. Results from various tests used to establish the baseline data are presented in tables.

  15. Experience with CANDID: Comparison algorithm for navigating digital image databases

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, P.; Cannon, M.

    1994-10-01

    This paper presents results from the authors experience with CANDID (Comparison Algorithm for Navigating Digital Image Databases), which was designed to facilitate image retrieval by content using a query-by-example methodology. A global signature describing the texture, shape, or color content is first computed for every image stored in a database, and a normalized similarity measure between probability density functions of feature vectors is used to match signatures. This method can be used to retrieve images from a database that are similar to a user-provided example image. Results for three test applications are included.

  16. Carbamylated Erythropoietin: A Prospective Drug Candidate for Neuroprotection.

    Science.gov (United States)

    Chen, Jianmin; Yang, Zheng; Zhang, Xiao

    2015-01-01

    Carbamylated erythropoietin (cEpo), which is neuroprotective but lacks hematopoietic activity, has been attracting rising concerns. However, the cellular and molecular mechanisms involved in the process of neuroprotection of cEpo are not well known. Based on several recent reports, the neuroprotective effects of cEpo are illustrated, and signaling pathways involved in the different effects of erythropoietin and cEpo are discussed. These newly reported researches may shed new light on the development and application of cEpo, a prospective drug candidate for neuroprotection. PMID:26862298

  17. Environmental Systems Research Candidates FY-01 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Miller, David Lynn; Piet, Steven James

    2001-03-01

    The Environmental Systems Research Candidates (ESRC) Program ran from April 2000 through September 2001 as part of the Environmental Systems Research and Analysis (ESRA) Program at the Idaho National Engineering and Environmental Laboratory (INEEL). ESRA provides key science and technology to meet the cleanup mission of the U.S. Department of Energy Office of Environmental Management (EM), and performs research and development that will help solve current legacy problems and enhance the INEEL’s scientific and technical capability for solving longer-term challenges. This report documents the accomplishments of the ESRC Program. The ESRC Program consisted of 25 tasks subdivided within four research areas.

  18. The Intrinsic Magnetic Fields of the Galactic Black Hole Candidates

    OpenAIRE

    Robertson, Stanley L.

    1998-01-01

    Recent work has linked the quiescent luminosities and hard/soft spectral state switches of neutron stars (NSs) to their spinning magnetic fields. It is shown here that the quiescent luminosities and spectral switches of galactic black hole candidates (BHCs) could be produced in the same way for spin rates below 100 Hz and magnetic fields above 10^10 G. It is also shown that the ultrasoft peaks and large flickering amplitudes of the BHCs would be expected from the surfaces of massive NSs. None...

  19. Event display of a H -> 4mu candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4mu candidate event with m(4l) = 124.1 (125.1) GeV without (with) Z mass constraint. The masses of the lepton pairs are 86.3 GeV and 31.6 GeV. The event was recorded by ATLAS on 10-Jun-2012, 13:24:31 CEST in run number 204769 as event number 71902630. Muon tracks are colored red. The inset on the right-hand side shows a zoom into the tracking detector. The inset on top shows a zoom into the vertex region, indicating that the 4 muons originate from the same primary vertex.

  20. Higgsphobic and fermiophobic Z’ as a single dark matter candidate

    OpenAIRE

    Nan Chen; Ying Zhang; Qing Wang; Giacomo Cacciapaglia; Aldo Deandrea; Luca Panizzi(School of Physics and Astronomy, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.)

    2014-01-01

    A spin-1 Z’ particle as a single dark matter candidate is investigated by assuming that it does not directly couple to the Higgs boson and standard model fermions and does not mix with the photon and Z boson. The remaining dominant vertices are quartic Z ′ Z ′ ZZ and Z ′ Z ′ W + W − , which can induce effective $ {Z^{\\prime }}{Z^{\\prime }}q\\overline{q} $ couplings through standard-model gauge-boson loops. We discuss constraints from the cosmological thermal relic density, and direct and indir...

  1. Discovery of Eleven Optical Nova Candidates in M81

    Science.gov (United States)

    Hornoch, K.; Sipocz, B.

    2012-01-01

    We report the discovery of five nova candidates in M81 found on a co-added 1100-s narrow-band H-alpha CCD image taken on 2012 Jan. 9.102 UT with the 2.54-m Isaac Newton Telescope (INT) at La Palma. The new objects are visible on the single frames used for the co-added image, but are not present on numerous narrow-band H-alpha archival images from the INT down to limiting magnitude as faint as H-alpha = 22.3.

  2. 2012 NCME Election of Board of Directors Candidate Biographies (in Alphabetical Order According to Position)

    Science.gov (United States)

    Educational Measurement: Issues and Practice, 2012

    2012-01-01

    This article profiles the candidates for the 2012 NCME election of board of directors. This includes the candidates for the office of the vice president and positions representing testing organizations and members at-large.

  3. Performance of women candidates on the American Board of Internal Medicine Certifying Examination, 1973-1982.

    Science.gov (United States)

    Norcini, J J; Fletcher, S W; Quimby, B B; Shea, J A

    1985-01-01

    Trends in the performances of female and male candidates taking the American Board of Internal Medicine Certifying Examination from 1973 through 1982 were examined. The mean scores of female candidates who graduated from medical schools in the United States or Canada and who were taking the examination for the first time improved from 428 to 470, and the percentage of those passing improved from 59% to 76%. The number of women taking the examination also increased markedly, by over 500%. Performance of female candidates remained slightly lower than that of male candidates, regardless of the quality of the residency training program or the medical school from which a candidate had graduated or the rating given a candidate by the director of the candidate's residency program. Except for the oldest candidates, age followed this pattern as well. Our findings suggest that the gender gap in scores on the Certifying Examination in Internal Medicine is narrowing.

  4. 77 FR 20886 - Proposed Information Collection (Advertising, Sales, and Enrollment Materials, and Candidate...

    Science.gov (United States)

    2012-04-06

    ... AFFAIRS Proposed Information Collection (Advertising, Sales, and Enrollment Materials, and Candidate... techniques or the use of other forms of information technology. Title: Advertising, Sales, and Enrollment... advertising, sales materials, enrollment materials, or candidate handbooks that educational institutions...

  5. Candidíase em pacientes aidéticos

    Directory of Open Access Journals (Sweden)

    C.E.O.P. Campos

    1992-09-01

    Full Text Available Trinta e cinco aidéticos entre 19 e 55 anos admitidos e tratados de candidíase no Hospital Emílio Ribas, SP, com ELISA positivo para HIV e confirmado pelo Western Blot. Tuberculose em 9 sendo 2 com pericardite; neurotoxoplasmose em 6; neurocriptococose em 5; herpes labial em 4; pneumocistose em 3 e sarcoma de Kaposi em 2, achavam-se associadas. A concentração inibitória mínima 50% (MIC 50% para os azoles foi: ketoconazol= 2,2 µg/ml; itraconazol- 21,0 µg/ml; fluconazol = 19,0 µg/ml. O MIC 50% para ospolienos: nistatina- 50,0 µg/ml; anfotericina B= 0,12 µg/ml e para 5 fluorcitosina= 1,6 µg/ml nas 35 amostras de Candida isoladas. Testes não paramétricos de Siegel revelaram significante identificação (80% das Candida albicans na candidíase, e que a dose de AMB não modificou o número de óbitos, precoce e tardio, ocorridos nesses aidéticos. O uso prévio dos azoles e da nistatina explicaria, talvez, o elevado MIC 50% observado nas amostras de Candida isoladas.

  6. Astrophysical dark matter: candidates from particle physics and detection possibilities

    International Nuclear Information System (INIS)

    In this talk, I will discuss the arguments that 50% to 90% of the matter in galaxies, including our own, is made of an unknown type of dark matter. I will review the reason why cosmologists believe Ω = 1 and illustrate the contrast with the limits on the amount of baryonic matter from element abundances in Big Bang Nucleosynthesis. Other arguments for nonbaryonic dark matter will also be discussed. Candidates for the dark matter from particle physics will be presented. I will focus on cold dark matter candidates known as WIMPs, weakly interacting massive (O(GeV)) particles. I will try to illustrate why these particles are interesting for astrophysics and outline ideas for cornering them. Detection possibilities for these particles include indirect detection, which takes advantage of the annihilation products of these particles in the galactic halo, the sun, or the earth. Direct detection via newly proposed cryogenic detectors must be sensitive to <∼ keV energy deposits. Annual modulation of the dark matter signal can be used as a signature for these halo particles. I hope to motivate the interest in these particles and discuss ideas for finding them

  7. Oxygen-Diffused Titanium as a Candidate Brake Rotor Material

    Energy Technology Data Exchange (ETDEWEB)

    Qu, Jun [ORNL; Blau, Peter Julian [ORNL; Jolly, Brian C [ORNL

    2009-01-01

    Titanium alloys are one of several candidate materials for the next generation of truck disk brake rotors. Despite their advantages of lightweight relative to cast iron and good strength and corrosion resistance, titanium alloys are unlikely to be satisfactory brake rotor materials unless their friction and wear behavior can be significantly improved. In this study, a surface engineering process oxygen diffusion was applied to titanium rotors and has shown very encouraging results. The oxygen diffused Ti-6Al-4V (OD-Ti) was tested on a sub-scale brake tester against a flat block of commercial brake lining material and benchmarked against several other Ti-based materials, including untreated Ti-6Al-4V, ceramic particle-reinforced Ti composites (MMCs), and a thermal-spray-coated Ti alloy. With respect to friction, the OD-Ti outperformed all other candidate materials under the imposed test conditions with the friction coefficient remaining within a desirable range of 0.35-0.50, even under the harshest conditions when the disk surface temperature reached nearly 600 C. In addition, the OD-Ti showed significantly improved wear-resistance over the non-treated one and was even better than the Ti-based composite materials.

  8. A computer vision based candidate for functional balance test.

    Science.gov (United States)

    Nalci, Alican; Khodamoradi, Alireza; Balkan, Ozgur; Nahab, Fatta; Garudadri, Harinath

    2015-08-01

    Balance in humans is a motor skill based on complex multimodal sensing, processing and control. Ability to maintain balance in activities of daily living (ADL) is compromised due to aging, diseases, injuries and environmental factors. Center for Disease Control and Prevention (CDC) estimate of the costs of falls among older adults was $34 billion in 2013 and is expected to reach $54.9 billion in 2020. In this paper, we present a brief review of balance impairments followed by subjective and objective tools currently used in clinical settings for human balance assessment. We propose a novel computer vision (CV) based approach as a candidate for functional balance test. The test will take less than a minute to administer and expected to be objective, repeatable and highly discriminative in quantifying ability to maintain posture and balance. We present an informal study with preliminary data from 10 healthy volunteers, and compare performance with a balance assessment system called BTrackS Balance Assessment Board. Our results show high degree of correlation with BTrackS. The proposed system promises to be a good candidate for objective functional balance tests and warrants further investigations to assess validity in clinical settings, including acute care, long term care and assisted living care facilities. Our long term goals include non-intrusive approaches to assess balance competence during ADL in independent living environments.

  9. Candidate plasma-facing materials for EUV lithography source components

    Science.gov (United States)

    Hassanein, Ahmed; Burtseva, Tatiana; Brooks, Jeff N.; Konkashbaev, Isak K.; Rice, Bryan J.

    2003-06-01

    Material selection and lifetime issues for extreme ultraviolet (EUV) lithography are of critical importance to the success of this technology for commercial applications. This paper reviews current trends in production and use of plasma-facing electrodes, insulators, and wall materials for EUV type sources. Ideal candidate materials should be able to: withstand high thermal shock from the short pulsed plasma; withstand high thermal loads without structural failure; reduce debris generation during discharge; and be machined accurately. We reviewed the literature on current and proposed fusion plasma-facing materials as well as current experience with plasma gun and other simulation devices. Both fusion and EUV source materials involve issues of surface erosion by particle sputtering and heat-induced evaporation/melting. These materials are either bare structural materials or surface coatings. EUV materials can be divided into four categories: wall, electrode, optical, and insulator materials. For electric discharge sources, all four types are required, whereas laser-produced plasma EUV sources do not require electrode and insulator materials. Several types of candidate alloy and other materials and methods of manufacture are recommended for each component of EUV lithography light sources.

  10. Photo multiplier tubes candidates for the Cherenkov telescope array project

    International Nuclear Information System (INIS)

    Photo Multiplier Tubes (PMTs) are the most wide spread detectors for fast low-level light signals. They are commonly used as standard light sensors for camera systems in imaging atmospheric Cherenkov telescopes. Years ago, an improvement program for the PMT candidates for the Cherenkov Telescope Array (CTA) project was initialized with the companies Hamamatsu Photonics K.K. (Japan) and Electron Tubes Enterprises Ltd. (England). CTA is the next generation of imaging atmospheric Cherenkov telescopes for high energy gamma ray astrophysics. Therefore, we need PMTs with outstanding good parameters concerning quantum efficiency, pulse width, after-pulsing and transit time spread. The currently available ''super-bialkali'' PMTs show a peak Quantum Efficiency of 40% and have an enhanced collection efficiency of up to 95-98% for wavelengths≥400 nm. The pulse width averages around 3ns at a gain of 40000. Also, the after-pulsing for a set threshold level of ≥4 photo electrons is reduced down to 0,02%. We report on the measurement results of PMT R-12292-100 from Hamamatsu as the final version and the intermediate version PMT D569/3SA from Electron Tubes Enterprises as candidate PMTs for the CTA project.

  11. A Catalog of Candidate High-redshift Blazars for GLAST

    Energy Technology Data Exchange (ETDEWEB)

    Arias, Tersi M.; /SLAC /San Francisco State U.

    2006-09-27

    High-redshift blazars are promising candidates for detection by the Gamma-ray Large Area Space Telescope (GLAST). GLAST, expected to be launched in the Fall of 2007, is a high-energy gamma-ray observatory designed for making observations of celestial gamma-ray sources in the energy band extending from 10 MeV to more than 200 GeV. It is estimated that GLAST will find several thousand blazars. The motivations for measuring the gamma-ray emission from distant blazars include the study of the high-energy emission processes occurring in these sources and an indirect measurement of the extragalactic background light. In anticipation of the launch of GLAST we have compiled a catalog of candidate high-redshift blazars. The criteria for sources chosen for the catalog were: high radio emission, high redshift, and a flat radio spectrum. A preliminary list of 307 radio sources brighter than 70mJy with a redshift z {ge} 2.5 was acquired using data from the NASA Extragalactic Database. Flux measurements of each source were obtained at two or more radio frequencies from surveys and catalogs to calculate their radio spectral indices {alpha}. The sources with a flat-radio spectrum ({alpha} {le} 0.5) were selected for the catalog, and the final catalog includes about 200 sources.

  12. Sleeping Beauty Mouse Models Identify Candidate Genes Involved in Gliomagenesis

    Science.gov (United States)

    Vyazunova, Irina; Maklakova, Vilena I.; Berman, Samuel; De, Ishani; Steffen, Megan D.; Hong, Won; Lincoln, Hayley; Morrissy, A. Sorana; Taylor, Michael D.; Akagi, Keiko; Brennan, Cameron W.; Rodriguez, Fausto J.; Collier, Lara S.

    2014-01-01

    Genomic studies of human high-grade gliomas have discovered known and candidate tumor drivers. Studies in both cell culture and mouse models have complemented these approaches and have identified additional genes and processes important for gliomagenesis. Previously, we found that mobilization of Sleeping Beauty transposons in mice ubiquitously throughout the body from the Rosa26 locus led to gliomagenesis with low penetrance. Here we report the characterization of mice in which transposons are mobilized in the Glial Fibrillary Acidic Protein (GFAP) compartment. Glioma formation in these mice did not occur on an otherwise wild-type genetic background, but rare gliomas were observed when mobilization occurred in a p19Arf heterozygous background. Through cloning insertions from additional gliomas generated by transposon mobilization in the Rosa26 compartment, several candidate glioma genes were identified. Comparisons to genetic, epigenetic and mRNA expression data from human gliomas implicates several of these genes as tumor suppressor genes and oncogenes in human glioblastoma. PMID:25423036

  13. ADAM33, a new candidate for psoriasis susceptibility.

    Directory of Open Access Journals (Sweden)

    Fabienne Lesueur

    Full Text Available Psoriasis is a chronic skin disorder with multifactorial etiology. In a recent study, we reported results of a genome-wide scan on 46 French extended families presenting with plaque psoriasis. In addition to unambiguous linkage to the major susceptibility locus PSORS1 on Chromosome 6p21, we provided evidence for a susceptibility locus on Chromosome 20p13. To follow up this novel psoriasis susceptibility locus we used a family-based association test (FBAT for an association scan over the 17 Mb candidate region. A total of 85 uncorrelated SNP markers located in 65 genes of the region were initially investigated in the same set of large families used for the genome wide search, which consisted of 295 nuclear families. When positive association was obtained for a SNP, candidate genes nearby were explored more in detail using a denser set of SNPs. Thus, the gene ADAM33 was found to be significantly associated with psoriasis in this family set (The best association was on a 3-SNP haplotype P = 0.00004, based on 1,000,000 permutations. This association was independent of PSORS1. ADAM33 has been previously associated with asthma, which demonstrates that immune system diseases may be controlled by common susceptibility genes with general effects on dermal inflammation and immunity. The identification of ADAM33 as a psoriasis susceptibility gene identified by positional cloning in an outbred population should provide insights into the pathogenesis and natural history of this common disease.

  14. Properties of optically selected BL Lac candidates from the SDSS

    CERN Document Server

    Kügler, S D; Heidt, J; Esser, J; Schultz, T

    2014-01-01

    \\textbf{Context.} Deep optical surveys open the avenue for find large numbers of BL Lac objects that are hard to identify because they lack the unique properties classifying them as such. While radio or X-ray surveys typically reveal dozens of sources, recent compilations based on optical criteria alone have increased the number of BL Lac candidates considerably. However, these compilations are subject to biases and may contain a substantial number of contaminating sources. \\textbf{Aims.} In this paper we extend our analysis of 182 optically selected BL Lac object candidates from the SDSS with respect to an earlier study. The main goal is to determine the number of bona fide BL Lac objects in this sample. \\textbf{Methods.} We examine their variability characteristics, determine their broad-band radio-UV SEDs, and search for the presence of a host galaxy. In addition we present new optical spectra for 27 targets with improved S/N with respect to the SDSS spectra. \\textbf{Results.} At least 59% of our targets h...

  15. Genetics of intracerebral hemorrhage: Insights from candidate gene approaches

    Directory of Open Access Journals (Sweden)

    Baoqiong Liu

    2012-01-01

    Full Text Available Intracerebral hemorrhage (ICH is a heterogeneous disease with genetic factors playing an important role. Association studies on a wide range of candidate pathways suggest a weak but significant effect for several alleles with ICH risk. Among the most widely investigated genes are those involved in the renin-angiotensin-aldosterone system (e.g., angiotensin-converting enzyme, coagulation pathway (e.g., Factor XIII, Factor VII, platelet-activating factor acetylhydrolase, Factor V Leiden, and beta1-tubulin, lipid metabolism (e.g., apolipoproteins (ApoE, Apo(a, ApoH, homocysteine metabolism (e.g., methylenetetrahydrofolate reductase, inflammation (e.g., interleukin-6 and tumor necrosis-alpha and other candidate pathways. To identify the robustness of the above associations with ICH, a search of Pubmed (1988 through December 2011 was performed, with searches limited to English-language studies conducted among adult human subjects. This article presents a review of the examined literature on the genetics of ICH.

  16. Gaia FGK Benchmark Stars: New Candidates At Low-Metallicities

    CERN Document Server

    Hawkins, Keith; Heiter, Ulrike; Soubiran, Caroline; Blanco-Cuaresma, Sergi; Casagrande, Luca; Gilmore, Gerry; Lind, Karin; Magrini, Laura; Masseron, Thomas; Pancino, Elena; Randich, Sofia; Worley, Clare C

    2016-01-01

    We have entered an era of large spectroscopic surveys in which we can measure, through automated pipelines, the atmospheric parameters and chemical abundances for large numbers of stars. Calibrating these survey pipelines using a set of "benchmark stars" in order to evaluate the accuracy and precision of the provided parameters and abundances is of utmost importance. The recent proposed set of Gaia FGK benchmark stars of Heiter et al. (2015) has no recommended stars within the critical metallicity range of $-2.0 <$ [Fe/H] $< -1.0$ dex. In this paper, we aim to add candidate Gaia benchmark stars inside of this metal-poor gap. We began with a sample of 21 metal-poor stars which was reduced to 10 stars by requiring accurate photometry and parallaxes, and high-resolution archival spectra. The procedure used to determine the stellar parameters was similar to Heiter et al. (2015) and Jofre et al. (2014) for consistency. The effective temperature (T$_{\\mathrm{eff}}$) of all candidate stars was determined using...

  17. Novel approaches to identify protective malaria vaccine candidates

    Directory of Open Access Journals (Sweden)

    Wan Ni eChia

    2014-11-01

    Full Text Available Efforts to develop vaccines against malaria have been the focus of substantial research activities for decades. Several categories of candidate vaccines are currently being developed for protection against malaria, based on antigens corresponding to the pre-erythrocytic, blood-stage or sexual stages of the parasite. Long lasting sterile protection from Plasmodium falciparum sporozoite challenge has been observed in human following vaccination with whole parasite formulations, clearly demonstrating that a protective immune response targeting predominantly the pre-erythrocytic stages can develop against malaria. However, most of vaccine candidates currently being investigated, which are mostly subunits vaccines, have not been able to induce substantial (>50% protection thus far. This is due to the fact that the antigens responsible for protection against the different parasite stages are still yet to be known and relevant correlates of protection have remained elusive. For a vaccine to be developed in a timely manner, novel approaches are required. In this article, we review the novel approaches that have been developed to identify the antigens for the development of an effective malaria vaccine.

  18. Speeding disease gene discovery by sequence based candidate prioritization

    Directory of Open Access Journals (Sweden)

    Porteous David J

    2005-03-01

    Full Text Available Abstract Background Regions of interest identified through genetic linkage studies regularly exceed 30 centimorgans in size and can contain hundreds of genes. Traditionally this number is reduced by matching functional annotation to knowledge of the disease or phenotype in question. However, here we show that disease genes share patterns of sequence-based features that can provide a good basis for automatic prioritization of candidates by machine learning. Results We examined a variety of sequence-based features and found that for many of them there are significant differences between the sets of genes known to be involved in human hereditary disease and those not known to be involved in disease. We have created an automatic classifier called PROSPECTR based on those features using the alternating decision tree algorithm which ranks genes in the order of likelihood of involvement in disease. On average, PROSPECTR enriches lists for disease genes two-fold 77% of the time, five-fold 37% of the time and twenty-fold 11% of the time. Conclusion PROSPECTR is a simple and effective way to identify genes involved in Mendelian and oligogenic disorders. It performs markedly better than the single existing sequence-based classifier on novel data. PROSPECTR could save investigators looking at large regions of interest time and effort by prioritizing positional candidate genes for mutation detection and case-control association studies.

  19. Four dual AGN candidates observed with the VLBA

    CERN Document Server

    Gabányi, K É; Frey, S; Komossa, S; Paragi, Z; Hong, X -Y; Shen, Z -Q

    2016-01-01

    According to hierarchical structure formation models, merging galaxies are expected to be seen in different stages of their coalescence. However, currently there are no straightforward observational methods neither to select nor to confirm a large number of dual active galactic nuclei (AGN) candidates. Most attempts involve the better understanding of double-peaked narrow emission line sources, to distinguish the objects where the emission lines originate from narrow-line kinematics or jet-driven outflows from those which might harbour dual AGN. We observed four such candidate sources with the Very Long Baseline Array (VLBA) at 1.5 GHz with $\\sim$ 10 milli-arcsecond angular resolution where spectral profiles of AGN optical emission suggested the existence of dual AGN. In SDSS J210449.13-000919.1 and SDSS J23044.82-093345.3, the radio structures are aligned with the optical emission features, thus the double-peaked emission lines might be the results of jet-driven outflows. In the third detected source SDSS J1...

  20. Self-gravitating disc candidates around massive young stars

    Science.gov (United States)

    Forgan, D. H.; Ilee, J. D.; Cyganowski, C. J.; Brogan, C. L.; Hunter, T. R.

    2016-11-01

    There have been several recent detections of candidate Keplerian discs around massive young protostars. Given the relatively large disc-to-star mass ratios in these systems, and their young ages, it is worth investigating their propensity to becoming self-gravitating. To this end, we compute self-consistent, semi-analytic models of putative self-gravitating discs for five candidate disc systems. Our aim is not to fit exactly the observations, but to demonstrate that the expected dust continuum emission from marginally unstable self-gravitating discs can be quite weak, due to high optical depth at the mid-plane even at millimetre wavelengths. In the best cases, the models produce `observable' disc masses within a factor of <1.5 of those observed, with mid-plane dust temperatures comparable to measured temperatures from molecular line emission. We find in two cases that a self-gravitating disc model compares well with observations. If these discs are self-gravitating, they satisfy the conditions for disc fragmentation in their outer regions. These systems may hence have as-yet-unresolved low-mass stellar companions, and are thus promising targets for future high angular resolution observations.

  1. No Evidence for Association between Amelogenesis Imperfecta and Candidate Genes

    Directory of Open Access Journals (Sweden)

    M Ghandehari Motlagh

    2009-03-01

    Full Text Available "nBackground: Amelogenesis imperfecta (AI is an inherited tooth disorder. Despite the fact that up to now, several gene muta­tions in MMP20, ENAM, AMELX and KLK4 genes have been reported to be associated with AI, many other genes sug­gested to be involved. The main objective of this study was to find the mutations in three major candidate genes including MMP20, ENAM and KLK4 responsible for AI from three Iranian families with generalized hypoplastic phenotype in all teeth. "nMethods: All exon/intron boundaries of subjected genes were amplified by polymerase chain reaction and subjected to direct sequencing."nResults: One polymorphisms was identified in KLK4 exon 2, in one family a homozygous mutation was found in the third base of codon 22 for serine (TCG>TCT, but not in other families. Although these base substitutions have been occurred in the signaling domain, they do not seem to influence the activity of KLK4 protein."nConclusion: Our results might support the further evidence for genetic heterogeneity; at least, in some AI cases are not caused by a gene in these reported candidate genes.

  2. Self-gravitating disc candidates around massive young stars

    CERN Document Server

    Forgan, D H; Cyganowski, C J; Brogan, C L; Hunter, T R

    2016-01-01

    There have been several recent detections of candidate Keplerian discs around massive young protostars. Given the relatively large disc-to-star mass ratios in these systems, and their young ages, it is worth investigating their propensity to becoming self-gravitating. To this end, we compute self-consistent, semi-analytic models of putative self-gravitating discs for five candidate disc systems. Our aim is not to fit exactly the observations, but to demonstrate that the expected dust continuum emission from marginally unstable self-gravitating discs can be quite weak, due to high optical depth at the midplane even at millimetre wavelengths. In the best cases, the models produce "observable" disc masses within a factor of <1.5 of those observed, with midplane dust temperatures comparable to measured temperatures from molecular line emission. We find in two cases that a self-gravitating disc model compares well with observations. If these discs are self-gravitating, they satisfy the conditions for disc fragm...

  3. Reliability of MRI findings in candidates for lumbar disc prosthesis

    International Nuclear Information System (INIS)

    Limited reliability data exist for localised magnetic resonance imaging (MRI) findings relevant to planning of treatment with lumbar disc prosthesis and later outcomes. We assessed the reliability of such findings in chronic low back pain patients who were accepted candidates for disc prosthesis. On pretreatment MRI of 170 patients (mean age 41 years; 88 women), three experienced radiologists independently rated Modic changes, disc findings and facet arthropathy at L3/L4, L4/L5 and L5/S1. Two radiologists rerated 126 examinations. For each MRI finding at each disc level, agreement was analysed using the kappa statistic and differences in prevalence across observers using a fixed effects model. All findings at L3/L4 and facet arthropathy at L5/S1 had a mean prevalence <10% across observers and were not further analysed, ensuring interpretable kappa values. Overall interobserver agreement was generally moderate or good (kappa 0.40-0.77) at L4-S1 for Modic changes, nucleus pulposus signal, disc height (subjective and measured), posterior high-intensity zone (HIZ) and disc contour, and fair (kappa 0.24) at L4/L5 for facet arthropathy. Posterior HIZ at L5/S1 and severely reduced subjective disc height at L4/L5 differed up to threefold in prevalence between observers (p < 0.0001). Intraobserver agreement was mostly good or very good (kappa 0.60-1.00). In candidates for disc prosthesis, mostly moderate interobserver agreement is expected for localised MRI findings. (orig.)

  4. Material Properties of Three Candidate Elastomers for Space Seals Applications

    Science.gov (United States)

    Bastrzyk, Marta B.; Daniels, Christopher C.; Oswald, Jay J.; Dunlap, Patrick H., Jr.; Steinetz, Bruce M.

    2010-01-01

    A next-generation docking system is being developed by the National Aeronautics and Space Administration (NASA) to support Constellation Space Exploration Missions to low Earth orbit (LEO), to the Moon, and to Mars. A number of investigations were carried out to quantify the properties of candidate elastomer materials for use in the main interface seal of the Low Impact Docking System (LIDS). This seal forms the gas pressure seal between two mating spacecraft. Three candidate silicone elastomer compounds were examined: Esterline ELA-SA-401, Parker Hannifin S0383-70, and Parker Hannifin S0899-50. All three materials were characterized as low-outgassing compounds, per ASTM E595, so as to minimize the contamination of optical and solar array systems. Important seal properties such as outgas levels, durometer, tensile strength, elongation to failure, glass transition temperature, permeability, compression set, Yeoh strain energy coefficients, coefficients of friction, coefficients of thermal expansion, thermal conductivity and diffusivity were measured and are reported herein.

  5. Alkyl hydroperoxide reductase: a candidate Helicobacter pylori vaccine.

    Science.gov (United States)

    O'Riordan, Avril A; Morales, Veronica Athie; Mulligan, Linda; Faheem, Nazia; Windle, Henry J; Kelleher, Dermot P

    2012-06-01

    Helicobacter pylori (H. pylori) is the most important etiological agent of chronic active gastritis, peptic ulcer disease and gastric cancer. The aim of this study was to evaluate the efficacy of alkyl hydroperoxide reductase (AhpC) and mannosylated AhpC (mAhpC) as candidate vaccines in the C57BL/6J mouse model of H. pylori infection. Recombinant AhpC was cloned, over-expressed and purified in an unmodified form and was also engineered to incorporate N and C-terminal mannose residues when expressed in the yeast Pichia pastoris. Mice were immunized systemically and mucosally with AhpC and systemically with mAhpC prior to challenge with H. pylori. Serum IgG responses to AhpC were determined and quantitative culture was used to determine the efficacy of vaccination strategies. Systemic prophylactic immunization with AhpC/alum and mAhpC/alum conferred protection against infection in 55% and 77.3% of mice, respectively. Mucosal immunization with AhpC/cholera toxin did not protect against infection and elicited low levels of serum IgG in comparison with systemic immunization. These data support the use of AhpC as a potential vaccine candidate against H. pylori infection. PMID:22512976

  6. Trinocular stereo vision method based on mesh candidates

    Science.gov (United States)

    Liu, Bin; Xu, Gang; Li, Haibin

    2010-10-01

    One of the most interesting goals of machine vision is 3D structure recovery of the scenes. This recovery has many applications, such as object recognition, reverse engineering, automatic cartography, autonomous robot navigation, etc. To meet the demand of measuring the complex prototypes in reverse engineering, a trinocular stereo vision method based on mesh candidates was proposed. After calibration of the cameras, the joint field of view can be defined in the world coordinate system. Mesh grid is established along the coordinate axes, and the mesh nodes are considered as potential depth data of the object surface. By similarity measure of the correspondence pairs which are projected from a certain group of candidates, the depth data can be obtained readily. With mesh nodes optimization, the interval between the neighboring nodes in depth direction could be designed reasonably. The potential ambiguity can be eliminated efficiently in correspondence matching with the constraint of a third camera. The cameras can be treated as two independent pairs, left-right and left-centre. Due to multiple peaks of the correlation values, the binocular method may not satisfy the accuracy of the measurement. Another image pair is involved if the confidence coefficient is less than the preset threshold. The depth is determined by the highest sum of correlation of both camera pairs. The measurement system was simulated using 3DS MAX and Matlab software for reconstructing the surface of the object. The experimental result proved that the trinocular vision system has good performance in depth measurement.

  7. Non-Vestoid candidates in the inner Main Belt

    Science.gov (United States)

    Moskovitz, Nicholas; Oszkiewicz, Dagmara; Skiff, Brian; Kankiewicz, Pawel; Licandro, Javier; Galiazzo, Mattia; Zeilinger, Werner

    2016-10-01

    Most Howardite-Eucrite-Diogenite (HED) meteorites (analogues to V-type asteroids) are thought to originate from asteroid (4) Vesta. However some HEDs show distinct oxygen isotope ratios and therefore are thought to originate from other asteroids. In this study we try to identify asteroids that may represent parent bodies of those mismatching HEDs. In particular the origin of the anomalous Bunburra Rockhole meteorite was traced back to the inner main asteroid belt, showing that there might be asteroids that are not genetically linked to the asteroid (4) Vesta (the main source of V-type asteroids and HED meteorites) in the inner main belt. In this work we identify V-type asteroids outside the dynamical Vesta family whose rotational properties (retrograde vs prograde rotation) suggest the direction of Yarkovsky drift that sets them apart from typical Vestoids and Vesta fugitives. Specificly Nesvorny et al. 2008 simulated escapes paths from the Vesta family and showed that typical Vesta fugitives in the inner main asteroid belt at semi-major axis a drift or showing Yarkovsky drift direction towards (4) Vesta are the best candidates for non-Vestoidal V-type asteroids and therefore parent bodies of anomalous HED. In this study we have performed accurate photometric observations and determined sense of rotation for several asteroids testing their links to Vesta and anomalous HED. We have found several potential non-Vestoid candidates. Those objects have to be studied in more detail to fully confirm their link to anomalous HEDs.

  8. Spectral analysis of Kepler SPB and Beta Cep candidate stars

    CERN Document Server

    Lehmann, H; Semaan, T; Gutiérrez, J; Smalley, B; Briquet, M; Shulyak, D; Tsymbal, V; de Cat, P

    2010-01-01

    We determine the fundamental parameters of SPB and Beta Cep candidate stars observed by the Kepler satellite mission and estimate the expected types of non-radial pulsators by comparing newly obtained high-resolution spectra with synthetic spectra computed on a grid of stellar parameters assuming LTE and check for NLTE effects for the hottest stars. For comparison, we determine Teff independently from fitting the spectral energy distribution of the stars obtained from the available photometry. We determine Teff, log(g), micro-turbulent velocity, vsin(i), metallicity, and elemental abundance for 14 of the 16 candidate stars, two of the stars are spectroscopic binaries. No significant influence of NLTE effects on the results could be found. For hot stars, we find systematic deviations of the determined effective temperatures from those given in the Kepler Input Catalogue. The deviations are confirmed by the results obtained from ground-based photometry. Five stars show reduced metallicity, two stars are He-stro...

  9. Bright low mass eclipsing binary candidates observed by STEREO

    CERN Document Server

    Wraight, K T; White, Glenn J; Norton, A J; Bewsher, D

    2012-01-01

    Observations from the Heliospheric Imagers (HI-1) on both the STEREO spacecraft have been analysed to search for bright low mass eclipsing binaries (EBs) and potential brown dwarf transits and to determine the radii of the companions. A total of 9 EB candidates have been found, ranging in brightness from V=6.59 mag to V=11.3 mag, where the radius of the companion appears to be less than 0.4 Rsol, with a diverse range of host temperatures, from 4074 K to 6925 K. Both components of one candidate, BD-07 3648, appear to be less than 0.4 Rsol and this represents a particularly interesting system for further study. The shapes of the eclipses in some cases are not clear enough to be certain they are total and the corresponding radii found should therefore be considered as lower limits. The EBs reported in this paper have either been newly found by the present analysis, or previously reported to be eclipsing by our earlier STEREO/HI-1 results. One of the new objects has subsequently been confirmed using archival Supe...

  10. Reliability of MRI findings in candidates for lumbar disc prosthesis

    Energy Technology Data Exchange (ETDEWEB)

    Berg, Linda; Espeland, Ansgar [Haukeland University Hospital, Department of Radiology, Bergen (Norway); University of Bergen, Section for Radiology, Department of Surgical Sciences, Bergen (Norway); Neckelmann, Gesche [Haukeland University Hospital, Department of Radiology, Bergen (Norway); Gjertsen, Oeivind [Oslo University Hospital, Department of Neuroradiology, Oslo (Norway); Hellum, Christian [Oslo University Hospital, Department of Orthopaedics, Oslo (Norway); University of Oslo, Department of Orthopaedics, Oslo (Norway); Johnsen, Lars G. [University Hospital of Trondheim, National Centre for Diseases of the Spine, Trondheim (Norway); University Hospital of Trondheim, Orthopaedic Department, Trondheim (Norway); Eide, Geir E. [Haukeland University Hospital, Centre for Clinical Research, Bergen (Norway); University of Bergen, Department of Public Health and Primary Health Care, Bergen (Norway)

    2012-07-15

    Limited reliability data exist for localised magnetic resonance imaging (MRI) findings relevant to planning of treatment with lumbar disc prosthesis and later outcomes. We assessed the reliability of such findings in chronic low back pain patients who were accepted candidates for disc prosthesis. On pretreatment MRI of 170 patients (mean age 41 years; 88 women), three experienced radiologists independently rated Modic changes, disc findings and facet arthropathy at L3/L4, L4/L5 and L5/S1. Two radiologists rerated 126 examinations. For each MRI finding at each disc level, agreement was analysed using the kappa statistic and differences in prevalence across observers using a fixed effects model. All findings at L3/L4 and facet arthropathy at L5/S1 had a mean prevalence <10% across observers and were not further analysed, ensuring interpretable kappa values. Overall interobserver agreement was generally moderate or good (kappa 0.40-0.77) at L4-S1 for Modic changes, nucleus pulposus signal, disc height (subjective and measured), posterior high-intensity zone (HIZ) and disc contour, and fair (kappa 0.24) at L4/L5 for facet arthropathy. Posterior HIZ at L5/S1 and severely reduced subjective disc height at L4/L5 differed up to threefold in prevalence between observers (p < 0.0001). Intraobserver agreement was mostly good or very good (kappa 0.60-1.00). In candidates for disc prosthesis, mostly moderate interobserver agreement is expected for localised MRI findings. (orig.)

  11. Recoiling Black Holes: Electromagnetic Signatures, Candidates, and Astrophysical Implications

    Directory of Open Access Journals (Sweden)

    S. Komossa

    2012-01-01

    Full Text Available Supermassive black holes (SMBHs may not always reside right at the centers of their host galaxies. This is a prediction of numerical relativity simulations, which imply that the newly formed single SMBH, after binary coalescence in a galaxy merger, can receive kick velocities up to several 1000 km/s due to anisotropic emission of gravitational waves. Long-lived oscillations of the SMBHs in galaxy cores, and in rare cases even SMBH ejections from their host galaxies, are the consequence. Observationally, accreting recoiling SMBHs would appear as quasars spatially and/or kinematically offset from their host galaxies. The presence of the “kicks” has a wide range of astrophysical implications which only now are beginning to be explored, including consequences for black hole and galaxy assembly at the epoch of structure formation, black hole feeding, and unified models of active galactic nuclei (AGN. Here, we review the observational signatures of recoiling SMBHs and the properties of the first candidates which have emerged, including follow-up studies of the candidate recoiling SMBH of SDSSJ092712.65+294344.0.

  12. Opinions of the physical education and sports candidate teachers about reading

    OpenAIRE

    Alev Yenal; Tacettin Hakan Yenal; Murat Ozsaker

    2012-01-01

    Abstract This research aimed at exploring reading habits, opinions and attitudes about reading of the candidate teachers who studied at School of Physical Education and Sports of Adnan Menderes University. A questionnaire form -the first part of which addressed demographic questions and the second part targeted at candidate teachers’ opinions and attitudes about reading- was administered to 102 candidate teachers who participated in the research voluntarily (female candidate teachers= 39 an...

  13. Candidate Quality, Pressure Group Endorsements, And The Nature Of Political Advertising

    OpenAIRE

    Wittman, Donald

    2005-01-01

    Candidates may vary in quality, where quality is some characteristic orthogonal to policy. This "simple modification" has for the most part defied integration into the Downsian framework. Here we add the following complicating factors. We consider the possibility that there are uninformed voters who are ignorant of the candidates' relative quality. However, a pressure group with inside information regarding the quality of the candidates may endorse one of the candidates as the high-quality ca...

  14. Voices of Teacher Candidates of Color on White Race Evasion: "I Worried about My Safety!"

    Science.gov (United States)

    Amos, Yukari Takimoto

    2016-01-01

    This qualitative study investigated the negative impacts minority teacher candidates receive from white teacher candidates in a required multicultural education class. The findings reveal that four teacher candidates of color had difficulty positioning themselves among the overwhelming silencing power of whiteness in the class. The white students…

  15. Examining Teacher Candidate Resistance to Diversity: What Can Teacher Educators Learn?

    Science.gov (United States)

    Rose, Dana Gregory; Potts, Ann D.

    2011-01-01

    How teachers interpret and respond to diverse students' cultural identities is critical to students' success. Therefore, teacher educators require candidates to gain experience with multicultural populations during fieldwork as a means of promoting candidates' sociocultural consciousness. What can teacher educators learn from candidate perceptions…

  16. Identifying the Relationship of Teacher Candidates' Humor Styles with Anxiety and Self-Compassion Levels

    Science.gov (United States)

    Aydin, Aydan

    2015-01-01

    Problem Statement: Teacher candidates who will soon be responsible for educating the future generations should possess certain characteristics. Specific teacher candidates should have specific characteristics taken into consideration: pre-school and primary teacher candidates should be seen as role models by younger students; psychological…

  17. Accommodations in Teacher Education: Perspectives of Teacher Candidates with Learning Disabilities and Their Faculty Advisors

    Science.gov (United States)

    Csoli, Karen; Gallagher, Tiffany L.

    2012-01-01

    This study of teacher candidates with learning disabilities profiles their experience in a teacher education program. Two teacher candidates and their faculty advisors offer perspectives at various points during the teacher education program. Findings indicate that the teacher candidates were able to complete their required courses when their…

  18. Examining Technology and Teaching Efficacy of Preservice Teacher Candidates: A Deliberate Course Design Model

    Science.gov (United States)

    Willis, Jana M.

    2015-01-01

    Training programs that improve technology self-efficacy of teacher candidates will better prepare candidates to overcome technology challenges with greater levels of confidence. The purpose of this study was to examine self-efficacy levels of preservice teacher candidates who participated in scaffolded technology training designed to establish and…

  19. Comparative Evaluation of Political Candidates: Implications for the Voter Decision Making Process.

    Science.gov (United States)

    Hellweg, Susan A.; King, Stephen W.

    A study was conducted to examine the evaluative criteria or schemata that voters use in making decisions about competing candidates. More specifically, the study sought to determine (1) whether the criteria that voters employ differ between the candidates, and (2) the relative importance of various candidate-specific criteria in the voting…

  20. The Effect of Designed Geometry Teaching Lesson to the Candidate Teachers' Van Hiele Geometric Thinking Level

    Science.gov (United States)

    Yilmaz, Gül Kaleli; Koparan, Timur

    2016-01-01

    The aim of this study is to find out how designed Geometry Teaching Lesson affects candidate teachers' Van Hiele Geometric Thinking Levels. For that purpose, 14 weeks long study was performed with 44 candidate teachers who were university students in Turkey. Van Hiele Geometric Thinking Test was applied to candidate teachers before and after…

  1. Dark Matter candidates in a baryogenesis inspired scenario

    International Nuclear Information System (INIS)

    It has recently been shown that the electroweak baryogenesis mechanism is feasible in Standard Model extensions containing extra fermions with large Yukawa couplings. We show that the lightest of these fermionic fields can naturally be a good candidate for cold dark matter. We find regions in the parameter space where the thermal relic abundance of this particle is compatible with the dark matter density of the Universe as determined by the WMAP experiment. We study direct and indirect dark matter detection for this model and compare with current experimental limits and prospects for upcoming experiments. We find, contrary to the standard lore, that indirect detection searches are more promising than direct ones, and they already exclude part of the parameter space

  2. Large screen approaches to identify novel malaria vaccine candidates.

    Science.gov (United States)

    Davies, D Huw; Duffy, Patrick; Bodmer, Jean-Luc; Felgner, Philip L; Doolan, Denise L

    2015-12-22

    Until recently, malaria vaccine development efforts have focused almost exclusively on a handful of well characterized Plasmodium falciparum antigens. Despite dedicated work by many researchers on different continents spanning more than half a century, a successful malaria vaccine remains elusive. Sequencing of the P. falciparum genome has revealed more than five thousand genes, providing the foundation for systematic approaches to discover candidate vaccine antigens. We are taking advantage of this wealth of information to discover new antigens that may be more effective vaccine targets. Herein, we describe different approaches to large-scale screening of the P. falciparum genome to identify targets of either antibody responses or T cell responses using human specimens collected in Controlled Human Malaria Infections (CHMI) or under conditions of natural exposure in the field. These genome, proteome and transcriptome based approaches offer enormous potential for the development of an efficacious malaria vaccine. PMID:26428458

  3. The Pentaquark Candidates in the Dynamical Diquark Picture

    CERN Document Server

    Lebed, Richard F

    2015-01-01

    Starting with the dynamical picture of the exotic $c\\bar c$-containing states $XY \\! Z$ as the confinement-induced hadronization of a rapidly separating pair of a compact diquark and antidiquark, we describe the pentaquark candidates $P_c^+(4380)$ and $P_c^+(4450)$ in terms of a confined but rapidly separating color-antitriplet diquark $cu$ and color-triplet "triquark" $\\bar c (ud)$. This separation explains the relatively small $P_c^+$ widths, despite these 5-quark systems lying far above both the $J/\\psi \\, p$ and $\\Lambda_c \\bar D^{(*)0}$ thresholds. The $P_c^+$ states are predicted to form isospin doublets with neutral partners $P_c^0$.

  4. Phosphate bonded ceramics as candidate final-waste-form materials

    International Nuclear Information System (INIS)

    Room-temperature setting phosphate-bonded ceramics were studied as candidate materials for stabilization of DOE low-level problem mixed wastes which cannot be treated by other established stabilization techniques. Phosphates of Mg, Mg-Na, Al and Zr were studied to stabilize ash surrogate waste containing RCRA metals as nitrates and RCRA organics. We show that for a typical loading of 35 wt.% of the ash waste, the phosphate ceramics pass the TCLP test. The waste forms have high compression strength exceeding ASTM recommendations for final waste forms. Detailed X-ray diffraction studies and differential thermal analyses of the waste forms show evidence of chemical reaction of the waste with phosphoric acid and the host matrix. The SEM studies show evidence of physical bonding. The excellent performance in the leaching tests is attributed to a chemical solidification and physical as well as chemical bonding of ash wastes in these phosphate ceramics

  5. Systematic errors in estimation of gravitational-wave candidate significance

    CERN Document Server

    Capano, Collin; Hu, Yi-Ming; Hendry, Martin; Messenger, Chris; Veitch, John

    2016-01-01

    We investigate the issue in determining the significance of candidate transient gravitational-wave events in a ground-based interferometer network. Given the presence of non-Gaussian noise artefacts in real data, the noise background must be estimated empirically from the data itself. However, the data also potentially contains signals, thus the background estimate may be overstated due to contributions from signals. It has been proposed to mitigate possible bias by removing single-detector data samples that pass a multi-detector consistency test from the background estimates. We conduct a high-statistics Mock Data Challenge to evaluate the effects of removing such samples, modelling a range of scenarios with plausible detector noise distributions and with a range of plausible foreground astrophysical signal rates. We consider the the two different modes: one in which coincident samples are removed, and one in which all samples are retained and used. Three algorithms were operated in both modes, show good con...

  6. Maximized ExoEarth Candidate Yields for Starshades

    CERN Document Server

    Stark, Christopher C; Lisman, Doug; Cady, Eric; Savransky, Dmitry; Roberge, Aki; Mandell, Avi M

    2016-01-01

    The design and scale of a future mission to directly image and characterize potentially Earth-like planets will be impacted, to some degree, by the expected yield of such planets. Recent efforts to increase the estimated yields, by creating observation plans optimized for the detection and characterization of Earth-twins, have focused solely on coronagraphic instruments; starshade-based missions could benefit from a similar analysis. Here we explore how to prioritize observations for a starshade given the limiting resources of both fuel and time, present analytic expressions to estimate fuel use, and provide efficient numerical techniques for maximizing the yield of starshades. We implemented these techniques to create an approximate design reference mission code for starshades and used this code to investigate how exoEarth candidate yield responds to changes in mission, instrument, and astrophysical parameters for missions with a single starshade. We find that a starshade mission operates most efficiently so...

  7. Candidate Identification and Interference Removal in SETI@home

    CERN Document Server

    Korpela, Eric J; Lebofsky, Matt; Siemion, Andrew; von Korff, Joshua; Bankay, Robert C; Werthimer, Dan; Anderson, David

    2011-01-01

    SETI@home, a search for signals from extraterrestrial intelligence, has been recording data at the Arecibo radio telescope since 1999. These data are sent via the Internet to the personal computers of volunteers who have donated their computers' idle time toward this search. To date, SETI@home volunteers have detected more than 4.2 billion potential signals. While essentially all of these potential signals are due to random noise processes, radio frequency interference (RFI), or interference processes in the SETI@home instrumentation, it is possible that a true extraterrestrial transmission exists within this database. Herein we describe the process of interference removal being implemented in the SETI@home post-processing pipeline, as well as those methods being used to identify candidates worthy of further investigation.

  8. Higgsphobic and fermiophobic Z' as a single dark matter candidate

    CERN Document Server

    Chen, Nan; Wang, Qing; Cacciapaglia, Giacomo; Deandrea, Aldo; Panizzi, Luca

    2014-01-01

    A spin-1 Z' particle as a single dark matter candidate is investigated by assuming that it does not directly couple to the Higgs boson and standard model fermions and does not mix with the photon and Z boson. The remaining dominant vertices are quartic Z'Z'ZZ and Z'Z'W+W-, which can induce effective Z'Z'q\\bar{q} couplings through standard-model gauge-boson loops. We discuss constraints from the cosmological thermal relic density, and direct and indirect-detection experiments, and find that a dark Z' can only exist above the W boson mass threshold, and the effective quartic coupling of Z'Z'VV is bounded in the region of 10^{-3}~10^{-2}.

  9. Biochemical Markers for Osteoarthritis: Is There any Promising Candidate?

    Directory of Open Access Journals (Sweden)

    Elif Aydın

    2016-04-01

    Full Text Available Osteoarthritis (OA is the most common degenerative joint disease. OA affects millions of individuals each year and becoming the most important cause of pain in geriatric population. Progressive destruction of articular cartilage is one of the prominent features of the disease. The diagnosis of OA is generally based on clinical and radiographical findings, which are insufficient to determine early-stage OA and predict disease course. There is a need for biomarkers that help clinicians early diagnose, assess disease activity, predict prognosis and monitor response to therapy. There are a growing number of publications regarding candidate markers in this field. The aim of this paper was to review recent studies on biochemical markers that reflect cartilage, synovial and bone turnover and their clinical use in patients with OA.

  10. Herschel Reveals Massive Cold Clump Candidates in NGC 7538

    Science.gov (United States)

    Fallscheer, Cassandra; Reid, Mike; Di Francesco, James; Martin, Peter; Hill, Tracey

    2013-07-01

    Observations of the high-mass star formation region NGC 7538 taken with the Herschel Space Observatory were made at 70, 160, 250, 350, and 500 micron as part of the Herschel imaging study of OB Young Stellar objects (HOBYS) Key Programme. Within the one square degree field, we identify 780 dense sources and classify 224 of those. With the intention of investigating the existence of cold massive starless or class 0-like clumps that would have the potential to form intermediate- to high-mass stars, we further isolate 13 clumps as the most likely candidates for follow-up studies. A peculiar feature in the observations is a large, nearly complete ring of material. The evacuated ring is of unknown origin and hosts a number of the detected sources.

  11. Vaccines for leishmaniasis: from proteome to vaccine candidates.

    Science.gov (United States)

    Schroeder, Juliane; Aebischer, Toni

    2011-01-01

    Leishmania spp. cause a wide spectrum of tropical diseases which are threatening an estimated 350 million people around the globe. While in most cases non-fatal, the disease is associated with high morbidity, social stigmata and poverty. However, the most severe form visceral leishmaniasis can be fatal if left untreated. Chemotherapeutics are available but show high toxicity, costs and are prone to resistance development due to prolonged treatment periods. Healing is associated with a life-long resistance to re-infection and this argues for the feasibility of vaccination. However, despite much effort, no such vaccine has become available yet. Here, the status of vaccine development in this field is briefly summarized before the focus is set on the promise of reverse vaccinology for anti-Leishmania vaccine development in the post-genomic era. We report on our own experience with this approach using an instructive example of successful candidate vaccine antigen identification.

  12. Noncommutativity inspired Black Holes as Dark Matter Candidate

    CERN Document Server

    Kováčik, Samuel

    2015-01-01

    We study black holes with a source that is almost point-like (blurred), rather than exactly point-like, which could be caused by the noncommutativity of 3-space. Depending on its mass, such object has either none, one or two event horizons. It possesses new properties, which become important on microscopic scale, in particular the temperature of its Hawking radiation does not increase infinitely as its mass goes to zero, but vanishes instead. Such frozen, extremely dense pieces of matter are good dark matter candidate. In addition, we introduce an object oscillating between frozen black hole and naked (softened) singularity, such objects can serve as constituents of dark matter too. We call it gravimond.

  13. Candidate eco-friendly gas mixtures for MPGDs

    CERN Document Server

    Saviano, Giovanna

    2015-01-01

    Modern gas detectors for the detection of elementary particles, and MPGDs in particular, require F-based gases for optimal performance. Recent regulations demand the use of environmentally unfriendly F-based gases to be limited or banned. This work investigates the properties of potential eco-friendly gas candidate replacements. The aim is to discuss some of the important properties of gases for MPGDs, to list and summarize basic properties of eco-friendly refrigerants from the literature available, to discuss their properties for materials compatibility and safe use, and to make a prediction on selected parameters (i.e., ionization potentials, ionization pairs, etc) crucial for the performance of gas detectors considered by making use of both known parametrizations and quantum chemistry simulation codes.

  14. On the occurrence of glitches in pulsar free precession candidates

    CERN Document Server

    Jones, D I; Prix, R

    2016-01-01

    The timing properties of radio pulsars provide a unique probe of neutron star interiors. Recent observations have uncovered quasi-periodicities in the timing and pulse properties of some pulsars, a phenomenon that has often been attributed to free precession of the neutron star, with profound implications for the distribution of superfluidity and superconductivity in the star. We advance this programme by developing consistency relations between free precession and pulsars glitches, and show that there are difficulties in reconciling the two phenomena in some precession candidates. This indicates that either the precession model used here needs to be modified, or some other phenomenon is at work in producing the quasi-periodicities, or even that there is something missing in terms of our understanding of glitches.

  15. Computational identification of candidate nucleotide cyclases in higher plants

    KAUST Repository

    Wong, Aloysius Tze

    2013-09-03

    In higher plants guanylyl cyclases (GCs) and adenylyl cyclases (ACs) cannot be identified using BLAST homology searches based on annotated cyclic nucleotide cyclases (CNCs) of prokaryotes, lower eukaryotes, or animals. The reason is that CNCs are often part of complex multifunctional proteins with different domain organizations and biological functions that are not conserved in higher plants. For this reason, we have developed CNC search strategies based on functionally conserved amino acids in the catalytic center of annotated and/or experimentally confirmed CNCs. Here we detail this method which has led to the identification of >25 novel candidate CNCs in Arabidopsis thaliana, several of which have been experimentally confirmed in vitro and in vivo. We foresee that the application of this method can be used to identify many more members of the growing family of CNCs in higher plants. © Springer Science+Business Media New York 2013.

  16. Piperidine renin inhibitors: from leads to drug candidates.

    Science.gov (United States)

    Märki, H P; Binggeli, A; Bittner, B; Bohner-Lang, V; Breu, V; Bur, D; Coassolo, P H; Clozel, J P; D'Arcy, A; Doebeli, H; Fischli, W; Funk, C H; Foricher, J; Giller, T; Grüninger, F; Guenzi, A; Güller, R; Hartung, T; Hirth, G; Jenny, C H; Kansy, M; Klinkhammer, U; Lave, T; Lohri, B; Luft, F C; Mervaala, E M; Müller, D N; Müller, M; Montavon, F; Oefner, C H; Qiu, C; Reichel, A; Sanwald-Ducray, P; Scalone, M; Schleimer, M; Schmid, R; Stadler, H; Treiber, A; Valdenaire, O; Vieira, E; Waldmeier, P; Wiegand-Chou, R; Wilhelm, M; Wostl, W; Zell, M; Zell, R

    2001-01-01

    Non-peptidomimetic renin inhibitors of the piperidine type represent a novel structural class of compounds potentially free of the drawbacks seen with peptidomimetic compounds so far. Synthetic optimization in two structural series focusing on improvement of potency, as well as on physicochemical properties and metabolic stability, has led to the identification of two candidate compounds 14 and 23. Both display potent and long-lasting blood pressure lowering effects in conscious sodium-depleted marmoset monkeys and double transgenic rats harboring both the human angiotensinogen and the human renin genes. In addition, 14 normalizes albuminuria and kidney tissue damage in these rats when given over a period of 4 weeks. These data suggest that treatment of chronic renal failure patients with a renin inhibitor might result in a significant improvement of the disease status. PMID:11347960

  17. Stress corrosion cracking of candidate waste container materials

    International Nuclear Information System (INIS)

    Six alloys have been selected as candidate container materials for the storage of high-level nuclear waste at the proposed Yucca Mountain site in Nevada. These materials are Type 304L stainless steel (SS), Type 316L SS, Incology 825, P-deoxidized Cu, Cu-30%Ni, and Cu-7% Al. The present program has been initiated to determine whether any of these materials can survive for 300 years in the site environment without developing through-wall stress corrosion cracks, and to assess the relative resistance of these materials to stress corrosion cracking (SCC). A series of slow-strain-rate tests (SSRTs) in simulated Well J-13 water which is representative of the groundwater present at the Yucca Mountain site has been completed, and crack-growth-rate (CGR) tests are also being conducted under the same environmental conditions. 13 refs., 60 figs., 22 tabs

  18. Spectroscopic analysis of four post-AGB candidates

    CERN Document Server

    Molina, R E; Pereira, C B; Ferro, A Arellano; Muneer, S

    2014-01-01

    We have done a detailed abundance analysis of four unexplored candidate post- Asymptotic Giant Branch(AGB) stars IRAS 13110 - 6629, IRAS 17579 - 3121, IRAS 18321 - 1401 and IRAS 18489 - 0629 using high resolution spectra. We have constructed Spectral Energy Distributions (SED) for these objects using the existing photometric data combined with infrared (IR) fluxes. For all sample stars, the SEDs exhibit double peaked energy distribution with well separated IR peaks showing the presence of dusty circumstellar material. The CNO abundances indicate the production of N via CN cycling, but observed [C/Fe] indicates the mixing of carbon produced by He burning by third dredge up although C/O ratio remains less that 1. A moderate DG effect is clearly seen for IRAS 18489 - 0629 and IRAS 17579 - 3121 while a large scatter observed in depletion plots for IRAS 18321 - 1401 and IRAS 13110 - 6629 indicate the presence of other processes affecting the observed abundance pattern.

  19. Annual Killifish Transcriptomics and Candidate Genes for Metazoan Diapause.

    Science.gov (United States)

    Thompson, Andrew W; Ortí, Guillermo

    2016-09-01

    Dormancy has evolved in all major metazoan lineages. It is critical for survival when environmental stresses are not conducive to growth, maturation, or reproduction. Embryonic diapause is a form of dormancy where development is reversibly delayed and metabolism is depressed. We report the diapause transcriptome of the annual killifish Nematolebias whitei, and compare gene expression between diapause embryos and free-living larvae to identify a candidate set of 945 differentially expressed "diapause" genes for this species. Similarity of transcriptional patterns among N. whitei and other diapausing animals is striking for a small set of genes associated with stress resistance, circadian rhythm, and metabolism, while other genes show discordant patterns. Although convergent evolution of diapause may require shared molecular mechanisms for fundamental processes, similar physiological phenotypes also may arise through modification of alternative pathways. Annual killifishes are a tractable model system for comparative transcriptomic studies on the evolution of diapause. PMID:27297470

  20. Event display of a H -> 4e candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4e candidate event with m(4l) = 124.5 (124.6) GeV without (with) Z mass constraint. The masses of the lepton pairs are 70.6 GeV and 44.7 GeV. The event was recorded by ATLAS on 18-May-2012, 20:28:11 CEST in run number 203602 as event number 82614360. The tracks and clusters of the two electron pairs are colored red and blue, respectively. The three displays on the right-hand side show the r-phi view of the event (top), a zoom into the vertex region, indicating that the 4 electrons originate from the same primary vertex (middle), and a Lego plot indicating the amount of transverse energy Et measured in the calorimeters (bottom).

  1. Event display of a H -> 4e candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display (side view) of a H -> 4e candidate event with m(4l) = 124.5 (124.6) GeV without (with) Z mass constraint. The masses of the lepton pairs are 70.6 GeV and 44.7 GeV. The event was recorded by ATLAS on 18-May-2012, 20:28:11 CEST in run number 203602 as event number 82614360. The tracks of the two electron pairs are colored red and blue, respectively. Electron clusters in the LAr calorimeter are colored darkgreen. The three displays on the right-hand side show the r-phi view of the event (top), a zoom into the vertex region, indicating that the 4 electrons originate from the same primary vertex (middle), and a Lego plot indicating the amount of transverse energy Et measured in the calorimeters (bottom).

  2. Space exploration initiative candidate nuclear propulsion test facilities

    Science.gov (United States)

    Baldwin, Darrell; Clark, John S.

    1993-01-01

    One-page descriptions for approximately 200 existing government, university, and industry facilities which may be available in the future to support SEI nuclear propulsion technology development and test program requirements are provided. To facilitate use of the information, the candidate facilities are listed both by location (Index L) and by Facility Type (Index FT). The included one-page descriptions provide a brief narrative description of facility capability, suggest potential uses for each facility, and designate a point of contact for additional information that may be needed in the future. The Nuclear Propulsion Office at NASA Lewis presently plans to maintain, expand, and update this information periodically for use by NASA, DOE, and DOD personnel involved in planning various phases of the SEI Nuclear Propulsion Project.

  3. Cathelicidin peptides as candidates for a novel class of antimicrobials.

    Science.gov (United States)

    Zanetti, Margherita; Gennaro, Renato; Skerlavaj, Barbara; Tomasinsig, Linda; Circo, Raffaella

    2002-01-01

    Cathelicidin peptides are a numerous group of mammalian cationic antimicrobial peptides. Despite a common evolutionary origin of their genes, peptides display a remarkable variety of sizes, sequences and structures. Their spectra of antimicrobial activity are varied and cover a range of organisms that includes bacteria, fungi and enveloped viruses. In addition, they bind to and neutralize the effects of endotoxin. These features make this family of peptides good candidates in view of a therapeutic use. The most promising ones are currently under evaluation as leads for the development of novel anti-infectives, and synthetic variants are in an advanced stage of development for specific clinical applications. This review focuses on recent studies on the structure and in vitro and in vivo biological activities of these peptides. PMID:11945171

  4. Vitamin D Status in Monkey Candidates for Space Flight

    Science.gov (United States)

    Arnaud, S. B.; Wronski, T. J.; Koslovskeya, I.; Dotsenko, R.; Navidi, M.; Wade, Charles E. (Technical Monitor)

    1994-01-01

    In preparation for the Cosmos 2229 Biosatellite space flight experiments in Rhesus monkeys, we evaluated the status of vitamin D in animals of different origins: candidates for space flight raised in Moscow (IMBP) and animals housed at Ames Research Ctr. (ARC) for pilot studies. Diets at IMBP were natural foods found by analysis to contain 1.4% Ca, 2.8% P andng/ml,p<.001) in IMBP than ARC animals. 1,25D (174156 vs. 212+77 pg/ml), Pi and AP were similar. In bone, osteoid and osteoblast surfaces averaged 38114% and 33+15% in all, with %vol. of osteoid higher in IMBP than ARC monkeys of the same BW (p<.05) Indices of bone formation were inversely related to 25D, not 1,25D. Of interest are similar 1,25D levels associated with a wide range of substrate and extensive osteoid in bone of D replete animals.

  5. Disformal scalars as dark matter candidates — Branon phenomenology

    Science.gov (United States)

    Cembranos, Jose A. R.; Maroto, Antonio L.

    2016-05-01

    Scalar particles coupled to the Standard Model fields through a disformal coupling arise in different theories, such as massive gravity or braneworld models. We will review the main phenomenology associated with such particles. Distinctive disformal signatures could be measured at colliders and with astrophysical observations. The phenomenological relevance of the disformal coupling demands the introduction of a set of symmetries, which may ensure the stability of these new degrees of freedom. In such a case, they constitute natural dark matter candidates since they are generally massive and weakly coupled. We will illustrate these ideas by paying particular attention to the branon case, since these questions arise naturally in braneworld models with low tension, where they were first discussed.

  6. Disformal scalars as dark matter candidates: Branon phenomenology

    CERN Document Server

    Cembranos, Jose A R

    2016-01-01

    Scalar particles coupled to the Standard Model fields through a disformal coupling arise in different theories, such as massive gravity or brane-world models. We will review the main phenomenology associated with such particles. Distinctive disformal signatures could be measured at colliders and with astrophysical observations. The phenomenological relevance of the disformal coupling demands the introduction of a set of symmetries, which may ensure the stability of these new degrees of freedom. In such a case, they constitute natural dark matter candidates since they are generally massive and weakly coupled. We will illustrate these ideas by paying particular attention to the branon case, since these questions arise naturally in brane-world models with low tension, where they were first discussed.

  7. Candidate materials performance under Supercritical Water Reactor (SCWR) conditions

    Energy Technology Data Exchange (ETDEWEB)

    Toivonen, A.; Penttilae, S.; Rissanen, L. (VTT Technical Research Centre of Finland, Espoo (Finland))

    2010-05-15

    The High Performance Light Water Reactor (HPLWR) is working at super-critical pressure (25 MPa) and a core coolant temperature up to 500 deg C. As an evolutionary step this reactor type follows the development path of modern supercritical coal-fired plants. This paper reviews the results on performance of commercial candidate materials for in-core applications focusing on corrosion, stress corrosion cracking (SCC) and creep issues. General corrosion (oxidation) tests with an inlet oxygen concentration of 125-150 ppb have been performed on several iron and nickel alloys at 300 to 650 deg C and 25 MPa in supercritical water. Stress corrosion cracking (SCC) susceptibility of selected austenitic stainless steels and a high chromium ODS (Oxide Dispersion Strengthened) alloy were also studied in slow strain rate tests (SSRT) in supercritical water at 500 deg C and 650 deg C. Furthermore, constant load creep tests have been performed on selected austenitic steels at 500 deg C and 650 deg C in supercritical water (25 MPa, 1 ppm O{sub 2}) and in an inert atmosphere (He, pressure 1 atm). Based on the materials studies, the current candidate materials for the core internals are austenitic steels with sufficient oxidation and creep resistance up to 500-550 deg C. High chromium austenitic steels and ODS alloys steels are considered for the fuel rod cladding due to their oxidation resistance up to 650 deg C. However, problems with manufacturing and joining of ODS alloys need to be solved. Alloys with high nickel content were not considered for the SCC or creep studies because of the strong effect of Ni on neutronics of the reactor core (orig.)

  8. Selection of Lactic Acid Bacteria as Probiotic Candidate for Chicken

    Directory of Open Access Journals (Sweden)

    F. Hamida

    2015-08-01

    Full Text Available Lactic acid bacteria (LAB regarded as safe microorganisms; they can naturally live in gastrointestinal tract, so appropriately used as a probiotic for chicken. This study aimed to select six isolates of LAB (E1223, E3, E4, E5, E7, and E8 to obtain the isolates potentially as probiotic candidate for chicken. The six isolates were derived from spontaneous fermented corn obtained from Laboratory of Animal Biotechnology and Biomedical, PPSHB, Bogor Agricultural University, Indonesia. LAB isolates were tested their susceptibility to antibiotics (bambermycin, erythromycin, chloramphenicol, and tetracycline then were examined in vitro for their tolerance to gastrointestinal pH (2, 3, 4, and 7.2 and 0.5% bile salt condition, antimicrobial activity against Salmonella enteritidis and Enterococcus casseliflavus, and ability to adhere to chicken ileal cells. The results showed the isolates E5, E7, and E8 were sensitive to tetracycline and chloramphenicol, they could survive at pH 2, 3, 4, and 7.2, could survive at 0.5% bile salts, produced antimicrobial activity, and able to adhere to ileal cells (9.40±0.00 Log CFU/cm2 of E8 and were significantly (P<0.05 higher than those of control (5.30±0.14 Log CFU/cm2. In conclusion, this study showed that isolate E8 had better potential compared to isolates E5 and E7 in most in vitro assays as a probiotic candidate for chicken. E5, E7, and E8 were closely related with Pediococcus pentosaceus based on 16S rRNA gene.

  9. Four Dual AGN Candidates Observed with the VLBA

    Science.gov (United States)

    Gabányi, K. É.; An, T.; Frey, S.; Komossa, S.; Paragi, Z.; Hong, X.-Y.; Shen, Z.-Q.

    2016-08-01

    According to hierarchical structure formation models, merging galaxies are expected to be seen in different stages of coalescence. However, there are currently no straightforward observational methods to either select or to confirm a large number of dual active galactic nucleus (AGN) candidates. Most attempts involve obtaining a better understanding of double-peaked narrow emission line sources, in order to distinguish the objects for which the emission lines originate from narrow-line kinematics or jet-driven outflows, from those which might harbor dual AGNs. We observed four such candidate sources with the Very Long Baseline Array (VLBA), at 1.5 GHz with a ∼10 mas angular resolution, for which the spectral profiles of AGN optical emission suggested the existence of dual AGNs. In SDSS J210449.13–000919.1 and SDSS J23044.82–093345.3 the radio structures are aligned with the optical emission features, thus the double-peaked emission lines might be the results of jet-driven outflows. In the third detected source SDSS J115523.74+150756.9, the radio structure is less extended and is oriented nearly perpendicular to the position angle derived from optical spectroscopy. The fourth source remained undetected with the VLBA, but it was imaged with the Very Large Array at arcsec resolution a few months before our observations, suggesting the existence of an extended radio structure. We did not detect two radio-emitting cores in any of the four sources, a convincing signature of duality.

  10. Adaptations to climate in candidate genes for common metabolic disorders.

    Directory of Open Access Journals (Sweden)

    Angela M Hancock

    2008-02-01

    Full Text Available Evolutionary pressures due to variation in climate play an important role in shaping phenotypic variation among and within species and have been shown to influence variation in phenotypes such as body shape and size among humans. Genes involved in energy metabolism are likely to be central to heat and cold tolerance. To test the hypothesis that climate shaped variation in metabolism genes in humans, we used a bioinformatics approach based on network theory to select 82 candidate genes for common metabolic disorders. We genotyped 873 tag SNPs in these genes in 54 worldwide populations (including the 52 in the Human Genome Diversity Project panel and found correlations with climate variables using rank correlation analysis and a newly developed method termed Bayesian geographic analysis. In addition, we genotyped 210 carefully matched control SNPs to provide an empirical null distribution for spatial patterns of allele frequency due to population history alone. For nearly all climate variables, we found an excess of genic SNPs in the tail of the distributions of the test statistics compared to the control SNPs, implying that metabolic genes as a group show signals of spatially varying selection. Among our strongest signals were several SNPs (e.g., LEPR R109K, FABP2 A54T that had previously been associated with phenotypes directly related to cold tolerance. Since variation in climate may be correlated with other aspects of environmental variation, it is possible that some of the signals that we detected reflect selective pressures other than climate. Nevertheless, our results are consistent with the idea that climate has been an important selective pressure acting on candidate genes for common metabolic disorders.

  11. Extremely metal-poor star candidates in the SDSS

    Institute of Scientific and Technical Information of China (English)

    Si-Yao Xu; Hua-Wei Zhang; Xiao-Wei Liu

    2013-01-01

    For a sample of metal-poor stars (-3.3 ≤ [Fe/H] ≤-2.2) that have highresolution spectroscopic abundance determinations,we have measured equivalent widths of the Ca Ⅱ K,Mg Ⅰ b and near-infrared Ca Ⅱ triplet lines using low-resolution spectra from the Sloan Digital Sky Survey (SDSS),calculated effective temperatures from (g-z)o color,deduced stellar surface gravities by fitting stellar isochrones,and determined metallicities based on the aforementioned quantities.Metallicities thus derived from the Ca Ⅱ K line are in much better agreement with the results determined from high-resolution spectra than the values given in the SDSS Data Release 7.The metallicities derived from the Mg Ⅰ b lines have a large dispersion owing to the large measurement errors,whereas those deduced from the Ca Ⅱ triplet lines are too high due to both non-local thermodynamical equilibrium (NLTE) effects and measurement errors.Abundances after correction for the NLTE effect for the Mg Ⅰ b lines and Ca Ⅱ triplet lines are also presented.Following this method,we have identified six candidates of ultra-metal-poor stars with [Fe/H] ~-4.0 from a sample of 166 metal-poor star candidates.One of them,SDSS J102915+172927,was recently confirmed to be an ultra-metal-poor ([Fe/H] <-4.0) star with the lowest metallicity ever measured.Follow-up high-resolution spectroscopy for the other five ultra-metal-poor stars in our sample will therefore be of great interest.

  12. Canister filling materials -- Design requirements and evaluation of candidate materials

    International Nuclear Information System (INIS)

    SKB has been evaluating a copper/steel canister for use in the disposal of spent nuclear reactor fuel. Once the canister is breached by corrosion, it is possible that the void volume inside the canister might fill with water. Water inside the canister would moderate the energy of the neutrons emitted by spontaneous fission in the fuel. It the space in the canister between and around the fuel pins is occupied by canister filling materials, the potential for criticality is avoided. The authors have developed a set of design requirements for canister filling material for the case where it is to be used alone, with no credit for burnup of the fuel or other measures, such as the use of neutron absorbers. Requirements were divided into three classes: essential requirements, desirable features, and undesirable features. The essential requirements are that the material fill at least 60% of the original void space, that the solubility of the filling material be less than 100 mg/l in pure water or expected repository waters at 50 C, and that the material not compact under its own weight by more than 10%. In this paper they review the reasons for these requirements, the desirable and undesirable features, and evaluate 11 candidate materials with respect to the design requirements and features. The candidate materials are glass beads, lead shot, copper spheres, sand, olivine, hematite, magnetite, crushed rock, bentonite, other clays, and concrete. Emphasis is placed on the determination of whether further work is needed to eliminate uncertainties in the evaluation of the ability of a particular filling material to be successfully used under actual conditions, and on the ability to predict the long-term performance of the material under the repository conditions

  13. A New Optical Survey of Supernova Remnant Candidates in M31

    CERN Document Server

    Lee, Jong Hwan

    2014-01-01

    We present a survey of optically emitting supernova remnants (SNRs) in M31 based on H$\\alpha$ and [SII] images in the Local Group Survey. Using these images, we select objects that have [SII]:H$\\alpha$ $>$ 0.4 and circular shapes. We find 76 new SNR candidates. We also inspect 234 SNR candidates presented in previous studies, finding that only 80 of them are SNR candidates according to our criteria. Combining them with the new candidates, we produce a master catalog of 156 SNR candidates in M31. We classify these SNR candidates according to two criteria: the SNR progenitor type [Type Ia and core-collapse (CC) SNRs] and the morphological type. Type Ia and CC SNR candidates make up 23% and 77%, respectively, of the total sample. Most of the CC SNR candidates are concentrated in the spiral arms, while the Type Ia SNR candidates are rather distributed over the entire galaxy, including the inner region. The CC SNR candidates are brighter in H$\\alpha$ and [SII] than the Type Ia SNR candidates. We derive a cumulativ...

  14. Diversity and Habitat Niche Modeling of Candidate Archaeal Phylum Aigarchaeota

    Science.gov (United States)

    Alba, T. W.; Goertz, G.; Williams, A. J.; Cole, J. K.; Murugapiran, S. K.; Dodsworth, J. A.; Hedlund, B. P.

    2013-12-01

    ';Aigarchaeota' (formerly known as pSL4 and Hot Water Crenarchaeotic Group I (HWCGI)) is a candidate phylum of Archaea known only by 16S rRNA gene fragments from cultivation-independent microbial surveys and a single composite genome from Candidatus ';Caldiarchaeum subterraneum', an inhabitant of a subterranean gold mine in Japan. Sequences reported in various publications are found exclusively in geothermal settings, but a comprehensive assessment has not yet been performed. We mined public databases for 16S rRNA gene sequences related to known ';Aigarchaeota' and used a combination of approaches to rigorously define the phylogenetic boundaries of the phylum. The analyses supported the proposed relationship between ';Aigarchaeota', Thaumarchaeota, Crenarchaeota, and Korarchaeota in the so-called 'TACK superphylum' and identified ~200 16S rRNA genes and gene fragments belonging to ';Aigarchaeota', including those recovered from terrestrial geothermal systems on several continents (North America, Asia, Africa, Europe, and Oceania) and marine geothermal and subsurface samples in both the Atlantic and Pacific. ';Aigarchaeota' belonged to at least three family- to order-level groups and at least seven genus-level groups. All genus-level groups were recovered from geographically distant locations, suggesting a global distribution within amenable habitats. ';Aigarchaeota'-specific primers for the polymerase chain reaction (PCR) amplification of 16S rRNA genes were designed using SP-Designer and reviewed using the Ribosomal Database Project Probe Match tool. The primers will be used to determine the presence and abundance of ';Aigarchaeota' in a wide variety of samples from terrestrial geothermal systems in the western U.S. and Asia. These phylogenetic data, along with a large geochemical database, will be analyzed using multivariate statistics to develop biogeographic and habitat niche models for ';Aigarchaeota'. This study offers the first coherent view of the

  15. Structure and evolution of barley powdery mildew effector candidates

    Directory of Open Access Journals (Sweden)

    Pedersen Carsten

    2012-12-01

    Full Text Available Abstract Background Protein effectors of pathogenicity are instrumental in modulating host immunity and disease resistance. The powdery mildew pathogen of grasses Blumeria graminis causes one of the most important diseases of cereal crops. B. graminis is an obligate biotrophic pathogen and as such has an absolute requirement to suppress or avoid host immunity if it is to survive and cause disease. Results Here we characterise a superfamily predicted to be the full complement of Candidates for Secreted Effector Proteins (CSEPs in the fungal barley powdery mildew parasite B. graminis f.sp. hordei. The 491 genes encoding these proteins constitute over 7% of this pathogen’s annotated genes and most were grouped into 72 families of up to 59 members. They were predominantly expressed in the intracellular feeding structures called haustoria, and proteins specifically associated with the haustoria were identified by large-scale mass spectrometry-based proteomics. There are two major types of effector families: one comprises shorter proteins (100–150 amino acids, with a high relative expression level in the haustoria and evidence of extensive diversifying selection between paralogs; the second type consists of longer proteins (300–400 amino acids, with lower levels of differential expression and evidence of purifying selection between paralogs. An analysis of the predicted protein structures underscores their overall similarity to known fungal effectors, but also highlights unexpected structural affinities to ribonucleases throughout the entire effector super-family. Candidate effector genes belonging to the same family are loosely clustered in the genome and are associated with repetitive DNA derived from retro-transposons. Conclusions We employed the full complement of genomic, transcriptomic and proteomic analyses as well as structural prediction methods to identify and characterize the members of the CSEPs superfamily in B. graminis f

  16. Afterpulse measurement for 8-inch candidate PMTs for LHAASO

    Science.gov (United States)

    Zhao, X.; Tang, Z.; Li, C.; Chen, H.; Zhang, Y.; Li, X.; Shao, M.; Sun, Y.; Zha, W.; Zhou, Y.

    2016-05-01

    An afterpulse occurs within a short time after the main pulse and cannot be directly distinguished from the true physical signals. In cosmic ray experiments, a large number of photomultiplier tubes (PMTs) are used, which means the occurrence of afterpulses leads to a significant background. Therefore, before PMTs are employed, their afterpulse characteristics need to be evaluated to make sure they perform as expected. To evaluate the impact of afterpulses, we investigate the afterpulses for the Hamamatsu PMT R5912 (a candidate of the WCDA and MD for LHAASO) using two different electronic testing systems. First, we measured the characteristics of afterpulses in detail using a frequency-tunable flash analog-to-digital converter (ADC) with a time window of up to 15 μ s after a laser signal. We measured the time delay with respect to the main pulse, the amplitude, and the rate of the afterpulse dependence, on the main signal amplitude and the applied high voltage. Second, we developed a system that uses a multi-hit time-to-digital converter (multi-hit TDC), which allows for much faster measurement of the afterpulse rates, in order to make it possible to test up to 5000 large-sized PMTs.

  17. Immunodiagnosis of porcine cysticercosis: identification of candidate antigens through immunoproteomics.

    Science.gov (United States)

    Diaz-Masmela, Yuliet; Fragoso, Gladis; Ambrosio, Javier R; Mendoza-Hernández, Guillermo; Rosas, Gabriela; Estrada, Karel; Carrero, Julio César; Sciutto, Edda; Laclette, Juan P; Bobes, Raúl J

    2013-12-01

    Cysticercosis, caused by the larval stage of Taenia solium, is a zoonotic disease affecting pigs and humans that is endemic to developing countries in Latin America, Africa and South East Asia. The prevalence of infection in pigs, the intermediate host for T. solium, has been used as an indicator for monitoring disease transmission in endemic areas. However, accurate and specific diagnostic tools for porcine cysticercosis remain to be established. Using proteomic approaches and the T. solium genome sequence, seven antigens were identified as specific for porcine cysticercosis, namely, tropomyosin 2, alpha-1 tubulin, beta-tubulin 2, annexin B1, small heat-shock protein, 14-3-3 protein, and cAMP-dependent protein kinase. None of these proteins were cross-reactive when tested with sera from pigs infected with Ascaris spp., Cysticercus tenuicollis and hydatid cysts of Echinococcus spp. or with serum from a Taenia saginata-infected cow. Comparison with orthologues, indicated that the amino acid sequences of annexin B1 and cAMP-dependent protein kinase possessed highly specific regions, which might make them suitable candidates for development of a specific diagnostic assay for porcine cysticercosis.

  18. Candidate transcriptomic sources of inbreeding depression in Drosophila melanogaster.

    Directory of Open Access Journals (Sweden)

    Carlos Garcia

    Full Text Available The genomic causes of inbreeding depression are poorly known. Several studies have found widespread transcriptomic alterations in inbred organisms, but it remains unclear which of these alterations are causes of the depression and which are mere responses to the ensuing physiological stress induced by increased homozygosity due to inbreeding. Attempting to differentiate causes from responses, we made a c-DNA microarray analysis of inbreeding depression in Drosophila melanogaster. The rationale of the experiment was that, while depression is a general phenomenon involving reductions in fitness in different inbred lines, its first genetic causes would be different for each inbred line, as they are expected to be caused by the fixation of rare deleterious genes. We took four sets of inbred sublines, each set descending from a different founding pair obtained from a large outbred stock, and compared the expression of the three most depressed sublines and the three least depressed sublines from each set. Many changes in expression were common to all sets, but fourteen genes, grouped in four expression clusters, showed strong set-specific changes, and were therefore possible candidates to be sources of the inbreeding depression observed.

  19. High-Resolution Observations of a Binary Black Hole Candidate

    Science.gov (United States)

    Tsai, Chao-Wei; Phillips, Chris; Norris, Ray; Jarrett, Thomas; Emonts, Bjorn; Cluver, Michelle; Eisenhardt, Peter; Stern, Daniel; Assef, Roberto

    2012-10-01

    We propose a 12-hour 2.3 GHz continuum Long Baseline Array (LBA) observation of WISE J2332-5056, a newly discovered supermassive black hole (SMBH) merger candidate that is located in the nearby universe (z = 0.3447). Our recently acquired 9 GHz ATCA map shows unusual radio morphology: a one-sided, smaller (and likely younger) FR-I jet perpendicular to a larger, Doppler-boosted FR-II jet. Follow-up Gemini-S/GMOS spectroscopy of this WISE-selected radio galaxy reveals broad emission lines blue-shifted by > 3,500 km/s with respect to the narrow lines and host galaxy, hallmarks of a dual AGN system. Combined, the optical spectroscopy and radio morphology of this object are strongly suggestive of a black hole merger system. Even in the local universe these systems are extremely difficult to identify; yet the process of supermassive blackhole growth is vital toward understanding galaxy evolution from the early to the current universe. Moreover, nearby merging SMBHs may serve as outstanding targets for gravitational wave studies. The proposed high resolution LBA map, reaching 50 pc resolution at the source redshift will allow us to investigate the SMBH merger scenario hypothesis.

  20. Spectroscopy of Young Planetary Mass Candidates with Disks

    CERN Document Server

    Jayawardhana, R; Jayawardhana, Ray; Ivanov, Valentin D.

    2006-01-01

    It is now well established that many young brown dwarfs exhibit characteristics similar to classical T Tauri stars, including infrared excess from disks and emission lines related to accretion. Whether the same holds true for even lower mass objects, namely those near and below the Deuterium-burning limit, is an important question. Here we present optical spectra of six isolated planetary mass candidates in Chamaeleon II, Lupus I and Ophiuchus star-forming regions, recently identified by Allers and collaborators to harbor substantial mid-infrared excesses. Our spectra, from ESO's Very Large Telescope and New Technology Telescope, show that four of the targets have spectral types in the ~M9-L1 range, and three of those also exhibit H_alpha. Their luminosities are consistent with masses of ~5-15 M_{Jupiter} according to models of Chabrier, Baraffe and co-workers, thus placing these four objects among the lowest mass brown dwarfs known to be surrounded by circum-sub-stellar disks. Our findings bolster the idea t...

  1. Cardiovascular Risk Assessment and Management in Prerenal Transplantation Candidates.

    Science.gov (United States)

    Lindley, Eric M; Hall, Amanda K; Hess, Jordan; Abraham, Jo; Smith, Brigham; Hopkins, Paul N; Shihab, Fuad; Welt, Frederick; Owan, Theophilus; Fang, James C

    2016-01-01

    Cardiovascular (CV) assessment in prerenal transplant patients varies by center. Current guidelines recommend stress testing for candidates if ≥ 3 CV risk factors exist. We evaluated the CV assessment and management in 685 patients referred for kidney transplant over a 7-year period. All patients had CV risk factors, and the most common cause of end-stage renal disease was diabetes. Thirty-three percent (n = 229) underwent coronary angiography. The sensitivity of stress testing to detect obstructive coronary artery disease (CAD) was poor (0.26). Patients who had no CAD, nonobstructive CAD, or CAD with intervention had significantly higher event-free survival compared with patients with obstructive CAD without intervention. There were no adverse clinical events (death, myocardial infarction, stroke, revascularization, and graft failure) within 30 days post-transplant in patients who had preoperative angiography (n = 77). Of the transplanted patients who did not have an angiogram (n = 289), there were 8 clinical events (6 myocardial infarctions) in the first 30 days. In conclusion, our results indicate that stress testing and usual risk factors were poor predictors of obstructive CAD and that revascularization may prove beneficial in these patients.

  2. Cystatin C: a candidate biomarker for amyotrophic lateral sclerosis.

    Directory of Open Access Journals (Sweden)

    Meghan E Wilson

    Full Text Available Amyotrophic lateral sclerosis (ALS is a fatal neurologic disease characterized by progressive motor neuron degeneration. Clinical disease management is hindered by both a lengthy diagnostic process and the absence of effective treatments. Reliable panels of diagnostic, surrogate, and prognostic biomarkers are needed to accelerate disease diagnosis and expedite drug development. The cysteine protease inhibitor cystatin C has recently gained interest as a candidate diagnostic biomarker for ALS, but further studies are required to fully characterize its biomarker utility. We used quantitative enzyme-linked immunosorbent assay (ELISA to assess initial and longitudinal cerebrospinal fluid (CSF and plasma cystatin C levels in 104 ALS patients and controls. Cystatin C levels in ALS patients were significantly elevated in plasma and reduced in CSF compared to healthy controls, but did not differ significantly from neurologic disease controls. In addition, the direction of longitudinal change in CSF cystatin C levels correlated to the rate of ALS disease progression, and initial CSF cystatin C levels were predictive of patient survival, suggesting that cystatin C may function as a surrogate marker of disease progression and survival. These data verify prior results for reduced cystatin C levels in the CSF of ALS patients, identify increased cystatin C levels in the plasma of ALS patients, and reveal correlations between CSF cystatin C levels to both ALS disease progression and patient survival.

  3. Identification of candidate millisecond pulsars from Fermi LAT observations

    Science.gov (United States)

    Dai, Xue-Jie; Wang, Zhong-Xiang; Vadakkumthani, Jithesh; Xing, Yi

    2016-06-01

    We report our detailed data analysis of 39 γ-ray sources selected from the 992 unassociated sources in the third Fermi Large Area Telescope Third Source Catalog. The selection criteria, which were set for finding candidate millisecond pulsars (MSPs), are non-variables with curved spectra and >5° Galactic latitudes. From our analysis, 24 sources were found to be point-like sources not contaminated by background or nearby unknown sources. Three of them, J1544.6–1125, J1625.1–0021 and J1653.6–0158, have been previously studied, indicating that they are likely MSPs. The spectra of J0318.1+0252 and J2053.9+2922 do not have properties similar to known γ-ray MSPs, and we thus suggest that they are not MSPs. Analysis of archival X-ray data for most of the 24 sources was also conducted. Four sources were found with X-ray objects in their error circles, and 16 with no detection. The ratios between the γ-ray fluxes and X-ray fluxes or flux upper limits are generally lower than those of known γ-ray MSPs, suggesting that if the γ-ray sources are MSPs, none of the X-ray objects are their counterparts. Deep X-ray or radio observations of these sources are needed in order to identify their MSP nature.

  4. Consortium analysis of 7 candidate SNPs for ovarian cancer

    DEFF Research Database (Denmark)

    Ramus, S.J.; Vierkant, R.A.; Johnatty, S.E.;

    2008-01-01

    The Ovarian Cancer Association Consortium selected 7 candidate single nucleotide polymorphisms (SNPs), for which there is evidence from previous studies of an association with variation in ovarian cancer or breast cancer risks. The SNPs selected for analysis were F31I (rs2273535) in AURKA, N372H...... was suggestive although no longer statistically significant (ordinal OR 0.92, 95% CI 0.79-1.06). This SNP has also been shown to have an association with decreased risk in breast cancer. There was a suggestion of an association for AURKA, when one study that caused significant study heterogeneity was excluded...... [ordinal OR 1.10 (95% CI 1.01-1.20) p = 0.027; dominant OR 1.12 (95% CI 1.01-1.24) p = 0.03]. The other 5 SNPs in BRCA2, CDKN2A, SRD5A2, CASP8 and TGFB1 showed no association with ovarian cancer risk; given the large sample size, these results can also be considered to be informative. These null results...

  5. Identification of Schistosoma mansoni candidate antigens for diagnosis of schistosomiasis

    Directory of Open Access Journals (Sweden)

    Gardenia Braz Figueiredo Carvalho

    2011-11-01

    Full Text Available The development of a more sensitive diagnostic test for schistosomiasis is needed to overcome the limitations of the use of stool examination in low endemic areas. Using parasite antigens in enzyme linked immunosorbent assay is a promising strategy, however a more rational selection of parasite antigens is necessary. In this study we performed in silico analysis of the Schistosoma mansoni genome, using SchistoDB database and bioinformatic tools for screening immunogenic antigens. Based on evidence of expression in all parasite life stage within the definitive host, extracellular or plasmatic membrane localization, low similarity to human and other helminthic proteins and presence of predicted B cell epitopes, six candidates were selected: a glycosylphosphatidylinositol-anchored 200 kDa protein, two putative cytochrome oxidase subunits, two expressed proteins and one hypothetical protein. The recognition in unidimensional and bidimensional Western blot of protein with similar molecular weight and isoelectric point to the selected antigens by sera from S. mansoni infected mice indicate a good correlation between these two approaches in selecting immunogenic proteins.

  6. Assessment of the candidate markets for liquid boiler fuels

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-12-01

    Liquid fuels can be produced from coal in a number of indirect and direct liquefaction processes. While indirect coal liquefaction has been proved commercially outside the United States, most attention in this country has focused on the direct liquefaction processes, which include the processes under examination in this report; namely, the Exxon Donor Solvent (EDS), the H-Coal, and the Solvent Refined Coal (SRC) II processes. The objectives of the study were to: compare the boiler fuels of direct coal liquefaction with residual fuel oil (No. 6 fuel oil) including physical characteristics and environmental hazards, such as carcinogenic characteristics and toxic hazard characteristics; determine whether a boiler fuel market would exist for the coal liquefaction products given their physical characteristics and potential environmental hazards; determine the advantages of utilizing methanol as a boiler fuel on a continuous basis in commercial boilers utilizing existing technology; identify the potential regional candidate markets for direct coal liquefaction products as liquid boiler fuels; determine the distributing and handling costs associated with marketing coal liquefaction products as liquid boiler fuels; determine the current regulatory issues associated with the marketing of coal liquefaction products as boiler fuels; and determine and evaluate other institutional issues associated with the marketing of direct coal liquefaction products as boiler fuels.

  7. The companion candidate near Fomalhaut - a background neutron star?

    CERN Document Server

    Neuhaeuser, Ralph; Ginski, Christian; Schmidt, Janos; Hambaryan, Valeri; Schmidt, Tobias

    2015-01-01

    The directly detected planetary mass companion candidate close to the young, nearby star Fomalhaut is a subject of intense discussion. While the detection of common proper motion led to the interpretation as Jovian-mass companion, later non-detections in the infrared raised doubts. Recent astrometric measurements indicate a belt crossing or highly eccentric orbit for the object, if a companion, making the planetary interpretation potentially even more problematic. In this study we discuss the possibility of Fomalhaut\\,b being a background object with a high proper motion. By analysing the available photometric and astrometric data of the object, we show that they are fully consistent with a neutron star: Neutron stars are faint, hot (blue), and fast moving. Neutron stars with an effective temperature of the whole surface area being 112,000 K to 126,500 K (with small to negligible extinction) at a distance of roughly 11 pc (best fit) would be consistent with all observables, namely with the photometric detecti...

  8. In silico Analysis of Candidate Genes Involved in Sanfilippo Syndrome

    Directory of Open Access Journals (Sweden)

    Mehreen Zaka

    2015-04-01

    Full Text Available Sanfilippo syndrome is an autosomal recessive lysosomal storage disorder, caused by the deficiency of enzymes that play an important role in degradation of glycosaminoglycans and also called mucopolysaccharidosis III. Mucopolysaccharidosis is genetic disorder. Here, we searched the candidate genes for Sanfilippo syndrome by using BLAST with the query sequence. As no suitable homology was found against the query sequence we moved towards threading approach. The threading approach was carried out by employing online CPH models and LOMETS tools. Through present research, domains of the proteins were predicted by utilizing the Domain Sweep tools, GNS and two domains were reported. Motif search reported the maximum number of motifs for Type D protein as compared to other types. All four proteins were totally soluble proteins and no transmembrane domains were found. In future, these results and predicted 3D structures can be used for the molecular docking studies, binding activities and protein-protein interactions for all the four types of Sanfilippo syndrome.

  9. Investigation of two candidate genes for Hailey-Hailey disease

    Energy Technology Data Exchange (ETDEWEB)

    Peluso, A.M.; Ikeda, S.; Bonifas, J.M. [Univ. of California, San Francisco, CA (United States)] [and others

    1994-09-01

    Hailey-Hailey disease (familial benign chronic pemphigus) is an autosomal dominant skin disease characterized by impaired keratinocyte cohesion and consequent blister formation. Recently we have used linkage to map the gene for this disease to a region of chromosome 3q between D3S1589 and D3S1316. The maximum combined two point lod score in four families studied was 14.60 at {theta} = 0 at the D3S1290 microsatellite repeat. Several genes have been mapped to chromosome 3q21-24, including cellular retinol binding protein (RBP1) and rhodopsin (RHO). Using microsatellite repeat for RHO we have found a recombinant with the RHO gene and Hailey-Hailey disease in one patient. Because of the profound effects of retinoids on epidermal differentiation, RBP1 could be considered as a possible candidate gene. We have amplified genomic DNA from patients from 14 individual families with Hailey-Hailey disease and 10 different control samples for each of the 4 exons of RBP1. Thus far, SSCP analysis has failed to detect different banding patterns in patients versus controls. We are now attempting to extend this RBP1 analysis and are collecting new families to use linkage analysis to narrow this still rather large (approximately 14 cM) interval.

  10. Factors influencing Turkish teacher candidates' elective course preferences

    Directory of Open Access Journals (Sweden)

    Duygu Uçgun

    2012-10-01

    Full Text Available By the Academic Year of 2006-2007, new curriculum has been begun to be applied in the Faculties of Education. When it is evaluated in terms of Turkish Language Teacher Training Departments, it is seen that the most attractive changes are the abolition of Side Branch application, the increase in the number of the courses which will contribute to teacher candidates’ profession and the enrichment in the content. In the curriculum are 5 elective courses beside necessary ones. The aim of this study is to determine what and how much effects the Turkish Language Teacher Candidates as they decide on the courses mentioned above. In the study, based on scanning method, of which subject is consists of 2nd, 3rd and 4th year students from Turkish Language Teacher Training Department, The Faculty of Education of Nigde University Likert-type Scale with four grades which was improved by Tezcan and Gumus (2008 has been used as data collection tool. According to the finding acquired from the study the factors effecting Turkish Language Teacher Candidates’ preferences about elective courses have been determined and ideas which are going to contribute to determination of elective courses and effective process of them have been suggested.

  11. Structure and kinematics of candidate double-barred galaxies

    CERN Document Server

    Moiseev, A V; Chavushyan, V H

    2003-01-01

    Results of optical and NIR spectral and photometric observations of a sample of candidate double-barred galaxies are presented. Velocity fields and velocity dispersion maps of stars and ionized gas, continuum and emission-line images were constructed from integral-field spectroscopy observations carried out at the 6m telescope (BTA) of SAO RAS, with the MPFS spectrograph and the scanning Fabry-Perot Interferometer. NGC2681 was also observed with long-slit spectrograph of the BTA. Optical and NIR images were obtained at the BTA and at the 2.1m telescope (OAN, M\\'exico). High-resolution images were retrieved from the HST data archive. Morphological and kinematic features of all 13 sample objects are described in detail. Attention is focused on the interpretation of observed non-circular motions of gas and stars in circumnuclear (one kiloparsec- scale) regions. We have shown first of all that these motions are caused by a gravitational potential of large-scale bar. NGC3368 and NGC3786 have nuclear bars only, the...

  12. Extreme BL Lacs: probes for cosmology and UHECR candidates

    CERN Document Server

    Tavecchio, F

    2015-01-01

    High-energy observations of extreme BL Lac objects, such as 1ES0229+200 or 1ES 0347-121, recently focused interest both for blazar and jet physics and for the implication on the extragalactic background light and intergalactic magnetic field estimate. Moreover, their enigmatic properties have been interpreted in a scenario in which their primary high- energy output is through a beam of high-energy hadrons. However, despite their possible important role in all these topics, the number of these extreme highly peaked BL Lac objects (EHBL) is still rather small. Aiming at increase their number, we selected a group of EHBL candidates considering those undetected (or only barely detected) by the LAT onboard Fermi and characterized by a high X-ray versus radio flux ratio. We assembled the multi-wavelength spectral energy distribution of the resulting 9 sources, using available archival data of Swift, GALEX, and Fermi satellites, confirming their nature. Through a simple one-zone synchrotron self-Compton model we est...

  13. Evidence For Intrinsic Magnetic Moments in Black Hole Candidates

    CERN Document Server

    Robertson, S L; Robertson, Stanley L.; Leiter, Darryl J.

    2002-01-01

    We show that the power law part of the quiescent x-ray emissions of neutron stars in low mass x-ray binaries is magnetospheric in origin. It can be very accurately calculated from rates of spin and the $\\sim 10^{3 - 4}$ times brighter luminosity at the transition to the hard spectral state. We establish that the spectral state transition for neutron stars is a magnetospheric propeller effect. We test the hypothesis that the similar spectral state switches and quiescent power law emissions of the black hole candidates might be magnetospheric effects. In the process we derive proposed magnetic moments and rates of spin for them and accurately predict their quiescent luminosities. We discuss other tests of the hypothesis and consider some attractive aspects of a unified magnetospheric model for low mass x-ray binaries. We also consider some of the changes that would be needed for strong-field gravity theories to accomodate intrinsic magnetic moments in collapsed objects.

  14. Abundances of metal-weak thick-disc candidates

    CERN Document Server

    Bonifacio, P; Molaro, P

    1999-01-01

    High resolution spectra of 5 candidate metal-weak thick-disc stars suggested by Beers & Sommer-Larsen (1995) are analyzed to determine their chemical abundances. The low abundance of all the objects has been confirmed with metallicity reaching [Fe/H]=-2.9. However, for three objects, the astrometric data from the Hipparcos catalogue suggests they are true halo members. The remaining two, for which proper-motion data are not available, may have disc-like kinematics. It is therefore clear that it is useful to address properties of putative metal-weak thick-disc stars only if they possess full kinematic data. For CS 22894-19 the abundance pattern similar to those of typical halo stars is found, suggesting that chemical composition is not a useful discriminant between thick-disc and halo stars. CS 29529-12 is found to be C enhanced with [C/Fe]=+1.0; other chemical peculiarities involve the s process elements: [Sr/Fe]=-0.65 and [Ba/Fe]=+0.62, leading to a high [Ba/Sr] considerably larger than what is found in ...

  15. Curcumin: A Natural Lead for Potential New Drug Candidates.

    Science.gov (United States)

    Oliveira, Ana Sofia; Sousa, Emília; Vasconcelos, Maria Helena; Pinto, Madalena

    2015-01-01

    Curcumin (1) is a secondary metabolite of turmeric, derived from Curcuma longa L. and was shown to have many biological activities. One of the most interesting properties of curcumin (1) is the antitumour activity allied with the ability to act as a multidrug resistance (MDR) modulator. Several curcumin derivatives have been synthesized with the purpose of discovering more information about the mechanisms of action, to establish structure-activity relationships (SAR), and to overcome pharmacokinetic problems. Over the past few decades, more potent and more stable curcumin derivatives have emerged with potential as drug candidates. Some important SAR studies pointed out that the unstable α,β-unsaturated diketone linker present in curcumin (1) may not be necessary for the antitumour activity; generally, shorter linkers result in more potent compounds than curcumin (1); the type of substituents and their substitution pattern are crucial regarding the biological activities of interest. Overall, the structure of curcumin (1) may represent an important basis for the development of more effective therapeutic agents, particularly in chemotherapy, as reflected by ongoing clinical trials. This article aims to review the synthesis and biological activities of curcumin (1) and derivatives, highlighting the MDR modulation properties of curcumin (1), since these effects makes this natural product a promising lead compound for the development of new anticancer drugs. PMID:26511469

  16. Identification of Novel Vaccine Candidates against Campylobacter through Reverse Vaccinology

    Science.gov (United States)

    Meunier, Marine; Guyard-Nicodème, Muriel; Chemaly, Marianne

    2016-01-01

    Campylobacteriosis is the most prevalent bacterial foodborne gastroenteritis affecting humans in the European Union. Human cases are mainly due to Campylobacter jejuni or Campylobacter coli, and contamination is associated with the handling and/or consumption of poultry meat. In fact, poultry constitutes the bacteria's main reservoir. A promising way of decreasing the incidence of campylobacteriosis in humans would be to decrease avian colonization. Poultry vaccination is of potential for this purpose. However, despite many studies, there is currently no vaccine available on the market to reduce the intestinal Campylobacter load in chickens. It is essential to identify and characterize new vaccine antigens. This study applied the reverse vaccinology approach to detect new vaccine candidates. The main criteria used to select immune proteins were localization, antigenicity, and number of B-epitopes. Fourteen proteins were identified as potential vaccine antigens. In vitro and in vivo experiments now need to be performed to validate the immune and protective power of these newly identified antigens. PMID:27413761

  17. Pre-Spectroscopic False Positive Elimination of Kepler Planet Candidates

    CERN Document Server

    Batalha, N M; Gilliland, R L; Jenkins, J J; Caldwell, D A; Borucki, W J; Koch, D G; Lissauer, J J; Dunham, E W; Gautier, T N; Howell, S B; Latham, D W; Marcy, G W; Prsa, A

    2010-01-01

    Ten days of commissioning data (Quarter 0) and thirty-three days of science data (Quarter 1) yield instrumental flux timeseries of ~150,000 stars that were combed for transit events, termed Threshold Crossing Events (TCE), each having a total detection statistic above 7.1-sigma. TCE light curves are modeled as star+planet systems. Those returning a companion radius smaller than 2R_J are assigned a KOI (Kepler Object of Interest) number. The raw flux, pixel flux, and flux-weighted centroids of every KOI are scrutinized to assess the likelihood of being an astrophysical false-positive versus the likelihood of a being a planetary companion. This vetting using Kepler data is referred to as data validation. Herein, we describe the data validation metrics and graphics used to identify viable planet candidates amongst the KOIs. Light curve modeling tests for a) the difference in depth of the odd- versus even-numbered transits, b) evidence of ellipsoidal variations, and c) evidence of a secondary eclipse event at pha...

  18. [Surgical evaluation of candidates for donation. Selection of the kidney].

    Science.gov (United States)

    Corral Molina, Juan M; Luque Gálvez, Pilar; Agud Piqué, Anna; Alcover García, Juan B

    2005-01-01

    Living donation for kidney transplantation is being promoted due to the shortage of organs, the improved outcomes of living donor transplants and the evolution of immunosuppression regimens. The process of organ donation from a living donor affects not only medical-surgical features but also emotional, social and economic. Using kidneys from living donors involves a great responsibility in evaluation and selection. Candidates for donation undergo an extensive set of examinations in order to optimize selection and to plan surgery. Radiological evaluation is one of the most important features of the evaluation process and selection of the kidney; it shows precisely the renal vascular anatomy, which is decisive in the choice of the kidney and helps to optimize the process and diminish risks and complications during extraction and/or tronsplantation. The advantages on imaging tests allow to evaluate potential donors in a safely, fast and almost noninvasive matter. The aim of the process is to select the kidney with less likelihood of failure due to technical reasons, and always leave the best kidney for the donor. PMID:16138762

  19. Candidate glutamatergic neurons in the visual system of Drosophila.

    Directory of Open Access Journals (Sweden)

    Shamprasad Varija Raghu

    Full Text Available The visual system of Drosophila contains approximately 60,000 neurons that are organized in parallel, retinotopically arranged columns. A large number of these neurons have been characterized in great anatomical detail. However, studies providing direct evidence for synaptic signaling and the neurotransmitter used by individual neurons are relatively sparse. Here we present a first layout of neurons in the Drosophila visual system that likely release glutamate as their major neurotransmitter. We identified 33 different types of neurons of the lamina, medulla, lobula and lobula plate. Based on the previous Golgi-staining analysis, the identified neurons are further classified into 16 major subgroups representing lamina monopolar (L, transmedullary (Tm, transmedullary Y (TmY, Y, medulla intrinsic (Mi, Mt, Pm, Dm, Mi Am, bushy T (T, translobula plate (Tlp, lobula intrinsic (Lcn, Lt, Li, lobula plate tangential (LPTCs and lobula plate intrinsic (LPi cell types. In addition, we found 11 cell types that were not described by the previous Golgi analysis. This classification of candidate glutamatergic neurons fosters the future neurogenetic dissection of information processing in circuits of the fly visual system.

  20. Photometry of some neglected bright cataclysmic variables and candidates

    CERN Document Server

    Bruch, Albert

    2016-01-01

    As part of an effort to better characterize bright cataclysmic variables (CVs) which have received little attention in the past light curves of four confirmed systems (CZ Aql, BO Cet, V380 Oph and EF Tuc) and one candidate (Lib 3) are analyzed. For none of these stars time resolved photometry has been published previously. While no variability was found in the case of Lib 3, which thus cannot be confirmed as a CV, the light curves of all other targets are dominated by strong flickering. Modulations on hourly time scales superimposed on the flickering can probably be related to orbital variations in BO Cet and V380 Oph, but not in CZ Aql and EF Tuc. Variations on the time scale of 10 minutes in CZ Aql, while not yet constituting convincing evidence, together with previous suspicions of a magnetically channeled accretion flow may point at an intermediate polar nature of this star. Some properties of the flickering are quantified in an effort to enlarge the data base for future comparative flickering studies in ...