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Sample records for cancer union del

  1. Union of {sup 99m} Tc-HYNIC-TOC at the somatostatin receptors in cells of pancreas cancer; Union del {sup 99m} Tc-HYNIC-TOC a los receptores de somatostatina en celulas de cancer de pancreas

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez C, J [Facultad de Medicina, UAEM, 50000 Toluca, Estado de Mexico (Mexico); Ramirez I, M T [INCMNSZ, Vasco de Quiroga Num. 15, Tlalpan, 14000 Mexico D.F. (Mexico); Ferro F, G; Pedraza L, M [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

    2005-07-01

    The radiation toxic effects have been used in therapy however much 50 years. The absorbed radiation dose can be determined at cellular level using cancerous cell cultures. If the deposited In vitro radiation dose coming from similar activities of several therapeutic radiopharmaceuticals it can compare it will be possible to choose the therapeutic radiopharmaceutical that it offers better dosimetric characteristics for the patient. The objective of this original investigation was to determine the union percentage of the octreotide {sup 99m}Tc-HYNlC-TOC to the somatostatin receivers in cells of cancer pancreas as well as the internalization, externalization and cellular viability. It was used the octapeptide, (octreotide, TOC) labelled with {sup 99m}Tc by means of the HYNIC chelating agent (6-hydrazine pyridine-3-carboxylic acid) and 3 cellular lines of murine pancreas cancer (AR42J), of cancer of human pancreas (CAPAN) and of one negative cellular line for somatostatin receivers (WRL-68). The {sup 99m}Tc-HYNIC-TOC was compared against two negative proofs for somatostatin receivers: the peptide {sup 99m}Tc-UBI and the {sup 99m}TcO{sub 4}. The cellular lines were conserved in the synthetic media Dulbecco-Eagle. After 2, 4 and 24 h of exhibition to the radiation, the cells are picked up and its are determined the viability by count in a Neubauer camera using tripan blue. In the same times it was calculated the union percentage of the radiopharmaceutical to the cells and the internalization (union to the cytoplasm) and the externalization (union to membrane receivers). With those figures it was calculated the absorbed radiation dose at cellular level. Results: At 4 hours the union percentage of the {sup 99m}Tc-HYNlC-TOC to the AR42-J cells was 6.83 times greater than for the WRL-68 control cells of human papilloma, (without receivers of the somatostatin) and for the CAPAN them 4 times greater than for the same cells used as negative control, for the case of the {sup 99m

  2. Union of {sup 99m} Tc-HYNIC-TOC at the somatostatin receptors in cells of pancreas cancer; Union del {sup 99m} Tc-HYNIC-TOC a los receptores de somatostatina en celulas de cancer de pancreas

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez C, J. [Facultad de Medicina, UAEM, 50000 Toluca, Estado de Mexico (Mexico); Ramirez I, M.T. [INCMNSZ, Vasco de Quiroga Num. 15, Tlalpan, 14000 Mexico D.F. (Mexico); Ferro F, G.; Pedraza L, M. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

    2005-07-01

    The radiation toxic effects have been used in therapy however much 50 years. The absorbed radiation dose can be determined at cellular level using cancerous cell cultures. If the deposited In vitro radiation dose coming from similar activities of several therapeutic radiopharmaceuticals it can compare it will be possible to choose the therapeutic radiopharmaceutical that it offers better dosimetric characteristics for the patient. The objective of this original investigation was to determine the union percentage of the octreotide {sup 99m}Tc-HYNlC-TOC to the somatostatin receivers in cells of cancer pancreas as well as the internalization, externalization and cellular viability. It was used the octapeptide, (octreotide, TOC) labelled with {sup 99m}Tc by means of the HYNIC chelating agent (6-hydrazine pyridine-3-carboxylic acid) and 3 cellular lines of murine pancreas cancer (AR42J), of cancer of human pancreas (CAPAN) and of one negative cellular line for somatostatin receivers (WRL-68). The {sup 99m}Tc-HYNIC-TOC was compared against two negative proofs for somatostatin receivers: the peptide {sup 99m}Tc-UBI and the {sup 99m}TcO{sub 4}. The cellular lines were conserved in the synthetic media Dulbecco-Eagle. After 2, 4 and 24 h of exhibition to the radiation, the cells are picked up and its are determined the viability by count in a Neubauer camera using tripan blue. In the same times it was calculated the union percentage of the radiopharmaceutical to the cells and the internalization (union to the cytoplasm) and the externalization (union to membrane receivers). With those figures it was calculated the absorbed radiation dose at cellular level. Results: At 4 hours the union percentage of the {sup 99m}Tc-HYNlC-TOC to the AR42-J cells was 6.83 times greater than for the WRL-68 control cells of human papilloma, (without receivers of the somatostatin) and for the CAPAN them 4 times greater than for the same cells used as negative control, for the case of the {sup 99m

  3. Economic Burden of Bladder Cancer Across the European Union.

    Science.gov (United States)

    Leal, Jose; Luengo-Fernandez, Ramon; Sullivan, Richard; Witjes, J Alfred

    2016-03-01

    More than 120,000 people are diagnosed annually with bladder cancer in the 28 countries of the European Union (EU). With >40,000 people dying of it each year, it is the sixth leading cause of cancer. However, to date, no systematic cost-of-illness study has assessed the economic impact of bladder cancer in the EU. To estimate the annual economic costs of bladder cancer in the EU for 2012. Country-specific cancer cost data were estimated using aggregate data on morbidity, mortality, and health care resource use, obtained from numerous international and national sources. Health care costs were estimated from expenditures on primary, outpatient, emergency, and inpatient care, as well as medications. Costs of unpaid care and lost earnings due to morbidity and early death were estimated. Bladder cancer cost the EU €4.9 billion in 2012, with health care accounting for €2.9 billion (59%) and representing 5% of total health care cancer costs. Bladder cancer accounted for 3% of all cancer costs in the EU (€143 billion) in 2012 and represented an annual health care cost of €57 per 10 EU citizens, with costs varying >10 times between the country with the lowest cost, Bulgaria (€8 for every 10 citizens), and highest cost, Luxembourg (€93). Productivity losses and informal care represented 23% and 18% of bladder cancer costs, respectively. The quality and availability of comparable cancer-related data across the EU need further improvement. Our results add to essential public health and policy intelligence for delivering affordable bladder cancer care systems and prioritising the allocation of public research funds. We looked at the economic costs of bladder cancer across the European Union (EU). We found bladder cancer to cost €4.9 billion in 2012, with health care accounting for €2.9 billion. Our study provides data that can be used to inform affordable cancer care in the EU. Copyright © 2015 European Association of Urology. Published by Elsevier B.V. All

  4. Quality assessments for cancer centers in the European Union.

    Science.gov (United States)

    Wind, Anke; Rajan, Abinaya; van Harten, Wim H

    2016-09-07

    Cancer centers are pressured to deliver high-quality services that can be measured and improved, which has led to an increase of assessments in many countries. A critical area of quality improvement is to improve patient outcome. An overview of existing assessments can help stakeholders (e.g., healthcare professionals, managers and policy makers) improve the quality of cancer research and care and lead to patient benefits. This paper presents key aspects of assessments undertaken by European cancer centers, such as: are assessments mandatory or voluntary? Do they focus on evaluating research, care or both? And are they international or national? A survey was sent to 33 cancer centers in 28 European Union member states. Participants were asked to score the specifics for each assessment that they listed. Based on the responses from 19 cancer centers from 18 member states, we found 109 assessments. The numbers have steadily increased from 1990's till 2015. Although, a majority of assessments are on patient-care aspects (n = 45), it is unclear how many of those include assessing patient benefits. Only few assessments cover basic research. There is an increasing trend towards mixed assessments (i.e., combining research and patient-care aspects) The need for assessments in cancer centers is increasing. To improve efforts in the quality of research and patient care and to prevent new assessments that "reinvent the wheel", it is advised to start comparative research into the assessments that are likely to bring patient benefits and improve patient outcome. Do assessments provide consistent and reliable information that create added value for all key stakeholders?

  5. Economic burden of cancer across the European Union: a population-based cost analysis.

    Science.gov (United States)

    Luengo-Fernandez, Ramon; Leal, Jose; Gray, Alastair; Sullivan, Richard

    2013-11-01

    In 2008, 2·45 million people were diagnosed with cancer and 1·23 million died because of cancer in the 27 countries of the European Union (EU). We aimed to estimate the economic burden of cancer in the EU. In a population-based cost analysis, we evaluated the cost of all cancers and also those associated with breast, colorectal, lung, and prostate cancers. We obtained country-specific aggregate data for morbidity, mortality, and health-care resource use from international and national sources. We estimated health-care costs from expenditure on care in the primary, outpatient, emergency, and inpatient settings, and also drugs. Additionally, we estimated the costs of unpaid care provided by relatives or friends of patients (ie, informal care), lost earnings after premature death, and costs associated with individuals who temporarily or permanently left employment because of illness. Cancer cost the EU €126 billion in 2009, with health care accounting for €51·0 billion (40%). Across the EU, the health-care costs of cancer were equivalent to €102 per citizen, but varied substantially from €16 per person in Bulgaria to €184 per person in Luxembourg. Productivity losses because of early death cost €42·6 billion and lost working days €9·43 billion. Informal care cost €23·2 billion. Lung cancer had the highest economic cost (€18·8 billion, 15% of overall cancer costs), followed by breast cancer (€15·0 billion, 12%), colorectal cancer (€13·1 billion, 10%), and prostate cancer (€8·43 billion, 7%). Our results show wide differences between countries, the reasons for which need further investigation. These data contribute to public health and policy intelligence, which is required to deliver affordable cancer care systems and inform effective public research funds allocation. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Invitation strategies and coverage in the population-based cancer screening programmes in the European Union.

    Science.gov (United States)

    Vale, Diama B; Anttila, Ahti; Ponti, Antonio; Senore, Carlo; Sankaranaryanan, Rengaswamy; Ronco, Guglielmo; Segnan, Nereo; Tomatis, Mariano; Žakelj, Maja P; Elfström, Klara M; Lönnberg, Stefan; Dillner, Joakim; Basu, Partha

    2018-03-21

    The aim of this study was to describe the compliance of the population-based cancer screening programmes in the European Union Member States to the invitation strategies enumerated in the European Guidelines and the impact of such strategies on the invitational coverage. Experts in screening programme monitoring from the respective countries provided data. Coverage by invitation was calculated as the proportion of individuals in the target age range receiving a screening invitation over the total number of annualized eligible population. The invitation strategies of 30 breasts, 25 cervical and 27 colorectal national or regional population-based screening programmes are described. Individual mail invitations are sent by 28 breasts, 20 cervical and 25 colorectal screening programmes. Faecal occult blood test kits are sent by post in 17 of the colorectal cancer screening programmes. The majority of programmes claimed to have a population registry, although some use health insurance data as the database for sending invitations. At least 95% invitation coverage was reached by 16 breast, six cervical and five colorectal screening programmes. Majority of the programmes comply with the invitation strategies enumerated in the European guidelines, although there is still scope for improvements. Coverage by invitation is below the desirable level in many population-based cancer screening programmes in European Union.

  7. Influencia del espesor de adhesivo de poliuretano en la resistencia de uniones sometidas a cortadura

    Directory of Open Access Journals (Sweden)

    García-Ledesma, R.

    2005-02-01

    Full Text Available The thickness of adhesive layers in metallic bonded joints has direct influence in the performance and mechanical behaviour of these joints. The aim of this study was to analyse the strength and strain properties of steel overlap joints bonded with polyurethane adhesive layers with different thickness. The results show that the strength is maximum when the thickness of the adhesive layer is very thin, 0.1 mm. When the thickness growth to 1 mm the strength goes down rapidly. For layers from 1 to 1.5 mm the strength goes down slower and from 1.5 to 4 mm the strength is nearly constant. In other hand, the joint strain increase uniformly with adhesive layer thickness growth.

    El espesor de la capa de adhesivo en las uniones por adhesión de materiales metálicos, tiene una influencia notable en el comportamiento y las propiedades mecánicas de dichas uniones. El objeto de este trabajo fue analizar las propiedades de resistencia y desplazamiento, presentadas por uniones a solape de acero, unidas con capas de diferentes espesores de un adhesivo de poliuretano. Los resultados obtenidos muestran que la resistencia mecánica es máxima para capas de adhesivo de espesor muy delgado: 0,1 mm. Cuando el espesor crece de 0,1 hasta 1 mm la resistencia disminuye rápidamente. Para capas desde 1 hasta 1,5 mm la resistencia disminuye más lentamente y, a partir de 1,5 mm, la resistencia permanece prácticamente constante. Por otro lado, los desplazamientos de la unión aumentan uniformemente a medida que crece el espesor de la capa de adhesivo.

  8. European Union pediatric legislation jeopardizes worldwide, timely future advances in the care of children with cancer.

    Science.gov (United States)

    Rose, Klaus

    2014-02-01

    Diagnosis of childhood cancer is no longer an automatic death sentence, but it has not lost all of its horror. Drugs, surgery, radiation, and clinical trials have advanced our capacity to handle these cancers, but pediatric cancers still face challenges. Pediatric pharmaceutical legislation was introduced in the United States in 1997 and has triggered many clinical trials that have helped us better understand what drugs do to a child's body and vice versa. Following the US precedence, the European Union introduced its own legislation. The US legislation was designed to generate additional pediatric data and balances between mandatory requirements and voluntary incentives. The US legislation was designed to mandate full registration of all new drugs for children whenever there is any potential pediatric use. The purpose of this article is to discuss unintended negative consequences of the legislation of the European Medicines Agency (EMA). We analyzed the effects of the EU pediatric legislation with respect to the history of the emergence of modern drugs, pediatric clinical pharmacology, and the development of drugs for pediatric malignancies. No new drug can be registered in the European Union without a detailed pediatric investigation plan (PIP) approved by the EMA's Pediatric Committee (PDCO). This has moved the discussion of the pediatric aspects of drug development to an earlier stage and has increased public awareness. It also has brought industry and pediatric oncologists closer together. However, in a review of >100 PDCO PIP decisions in childhood cancer, we found a lack of balance between the legitimate desire to include children in drug development and the common sense needed in the complex worlds of drug development and pediatric oncology. Many decisions appeared to have been based on both exaggerated assumptions about the frequency of childhood malignancies and the feasibility of the clinical trials proposed. Pharmaceutical companies are being forced

  9. Del-1 overexpression potentiates lung cancer cell proliferation and invasion

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung-Hwan; Kim, Dong-Young; Jing, Feifeng; Kim, Hyesoon [Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul (Korea, Republic of); Yun, Chae-Ok [Department of Bioengineering, College of Engineering, Hanyang University, Seoul (Korea, Republic of); Han, Deok-Jong [Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of); Choi, Eun Young, E-mail: choieun@ulsan.ac.kr [Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul (Korea, Republic of)

    2015-12-04

    Developmental endothelial locus-1 (Del-1) is an endogenous anti-inflammatory molecule that is highly expressed in the lung and the brain and limits leukocyte migration to these tissues. We previously reported that the expression of Del-1 is positively regulated by p53 in lung endothelial cells. Although several reports have implicated the altered expression of Del-1 gene in cancer patients, little is known about its role in tumor cells. We here investigated the effect of Del-1 on the features of human lung carcinoma cells. Del-1 mRNA was found to be significantly decreased in the human lung adenocarcinoma cell lines A549 (containing wild type of p53), H1299 (null for p53) and EKVX (mutant p53), compared to in human normal lung epithelial BEAS-2B cells and MRC-5 fibroblasts. The decrease of Del-1 expression was dependent on the p53 activity in the cell lines, but not on the expression of p53. Neither treatment with recombinant human Del-1 protein nor the introduction of adenovirus expressing Del-1 altered the expression of the apoptosis regulators BAX, PUMA and Bcl-2. Unexpectedly, the adenovirus-mediated overexpression of Del-1 gene into the lung carcinoma cell lines promoted proliferation and invasion of the lung carcinoma cells, as revealed by BrdU incorporation and transwell invasion assays, respectively. In addition, overexpression of the Del-1 gene enhanced features of epithelial–mesenchymal transition (EMT), such as increasing vimentin while decreasing E-cadherin in A549 cells, and increases in the level of Slug, an EMT-associated transcription regulator. Our findings demonstrated for the first time that there are deleterious effects of high levels of Del-1 in lung carcinoma cells, and suggest that Del-1 may be used as a diagnostic or prognostic marker for cancer progression, and as a novel therapeutic target for lung carcinoma. - Highlights: • Developmental Endothelial Locus-1 (Del-1) expression is downregulated in human lung cancer cells.

  10. Del-1 overexpression potentiates lung cancer cell proliferation and invasion

    International Nuclear Information System (INIS)

    Lee, Seung-Hwan; Kim, Dong-Young; Jing, Feifeng; Kim, Hyesoon; Yun, Chae-Ok; Han, Deok-Jong; Choi, Eun Young

    2015-01-01

    Developmental endothelial locus-1 (Del-1) is an endogenous anti-inflammatory molecule that is highly expressed in the lung and the brain and limits leukocyte migration to these tissues. We previously reported that the expression of Del-1 is positively regulated by p53 in lung endothelial cells. Although several reports have implicated the altered expression of Del-1 gene in cancer patients, little is known about its role in tumor cells. We here investigated the effect of Del-1 on the features of human lung carcinoma cells. Del-1 mRNA was found to be significantly decreased in the human lung adenocarcinoma cell lines A549 (containing wild type of p53), H1299 (null for p53) and EKVX (mutant p53), compared to in human normal lung epithelial BEAS-2B cells and MRC-5 fibroblasts. The decrease of Del-1 expression was dependent on the p53 activity in the cell lines, but not on the expression of p53. Neither treatment with recombinant human Del-1 protein nor the introduction of adenovirus expressing Del-1 altered the expression of the apoptosis regulators BAX, PUMA and Bcl-2. Unexpectedly, the adenovirus-mediated overexpression of Del-1 gene into the lung carcinoma cell lines promoted proliferation and invasion of the lung carcinoma cells, as revealed by BrdU incorporation and transwell invasion assays, respectively. In addition, overexpression of the Del-1 gene enhanced features of epithelial–mesenchymal transition (EMT), such as increasing vimentin while decreasing E-cadherin in A549 cells, and increases in the level of Slug, an EMT-associated transcription regulator. Our findings demonstrated for the first time that there are deleterious effects of high levels of Del-1 in lung carcinoma cells, and suggest that Del-1 may be used as a diagnostic or prognostic marker for cancer progression, and as a novel therapeutic target for lung carcinoma. - Highlights: • Developmental Endothelial Locus-1 (Del-1) expression is downregulated in human lung cancer cells.

  11. Rol de las uniones estrechas del epitelio intestinal en la patogenia de la enfermedad de Crohn

    Directory of Open Access Journals (Sweden)

    Dionisio Díaz

    2015-11-01

    In his review the molecular composition, structure, interactions and function of the tight junctions are briefly described, and recent evidence on the relationship between the dysfunction of the tight junctions and Crohn’s disease is commented. The role of microbiota in the regulation of tight junctions and the participation of tight junctions deregulation in the development of cancer associated to Crohn’s disease are also detailed. Finally, recent findings about the employment of tight junctions as targets for the development of new drugs are described.

  12. Cancer drug development and the evolving regulatory framework for companion diagnostics in the European union.

    Science.gov (United States)

    Pignatti, Francesco; Ehmann, Falk; Hemmings, Robert; Jonsson, Bertil; Nuebling, Micha; Papaluca-Amati, Marisa; Posch, Martin; Rasi, Guido

    2014-03-15

    The European Union (EU) legal framework for medical device regulation is currently under revision. The European Commission has proposed a new framework to ensure that medical devices serve the needs and ensure the safety of European citizens, aiming for a framework that is fit for purpose, more transparent, and better adapted to scientific and technological progress. The proposed new framework is described as an evolution of the current regime keeping the same legal approach. An important proposed change is that companion diagnostics will no longer be considered as low risk and subject to self-certification by the manufacturer. According to the new proposal, companion diagnostics will be classified as high individual risk or moderate public health risk (category C) and require conformity assessment by a notified body. It has also been proposed that evidence of the clinical utility of the device for the intended purpose should be required for companion diagnostics. In this article, we review the EU legal framework relevant for companion diagnostics, describe the proposed changes, and summarize the available scientific guidance from the European Medicines Agency and its regulatory experience with cancer drug development including companion diagnostics. See all articles in this CCR Focus section, "The Precision Medicine Conundrum: Approaches to Companion Diagnostic Co-development." ©2014 AACR.

  13. Intellectual Capital management model in energetical world. The case of Union Fenosa; La gestion del capital intelectual en un grupo energetico. El caso de Union Fenosa

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez Izard, J. A.

    2005-07-01

    The energy, services and technology group, Union Fenosa has grown during recent year staking advantage of knowledge acquired in its own transformation process. In which appropriate intangible management has played a major role. In 1999, a project was started in order to elaborate an intellectual Capital management model elaborate an intellectual Capital management model based on three capitals, human, structural and relational. Following 5 years of experience, the model has proved itself as a powerful communication and management tool to transmit to analysts, market and employees the value of intangible within the Group. (Author)

  14. IAEA Nobel Prize money fights cancer crisis in Latin America; Los fondos provenientes del Premio Nobel otorgado al OIEA se destinan a combatir el cancer en America Latina

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-04-18

    (ACS); Eduardo Cazap, President, Sociedad Latinoamericana y del Caribe de Oncologia Me dica (SLACOM), International Union Against Cancer (UICC)/ International Network for Cancer Treatment and Research (INCTR). Sessions will focus on comprehensive cancer control, evidence-based radiation oncology emerging techniques in radiotherapy planning and delivery. All sessions of the five-day meeting are open to journalists. Please note that only the first two days will be conducted in English and Spanish while days 3-5 will be conducted only in Spanish. (IAEA) [Spanish] El Organismo Internacional de Energia Atomica (OIEA) reunira a mas de 60 de los principales expertos mundiales sobre el cancer en Buenos Aires, del 23 al 27 de abril, para evaluar la creciente carga que representa esta enfermedad en America Latina. Los deficientes servicios medicos y la falta de personal cualificado y de financiacion estan limitando la capacidad de los paises para ampliar sus servicios de atencion oncologica y ofrecer tratamiento a los pacientes, en tanto se preve una duplicacion de las tasas de cancer para 2020. Mas del 70% de todas las muertes por cancer se producen en paises con ingresos bajos y medianos, y a escala mundial el cancer provoca mas muertes que el SIDA, la malaria y la tuberculosis en conjunto. A traves de su Programa de accion para la terapia contra el cancer (PACT) el OIEA esta utilizando fondos de la dotacion del Premio Nobel de la Paz, que recibio en 2005, para patrocinar talleres, como el de Buenos Aires, que senalen a encargados de formular politicas y expertos en salud la apremiante necesidad de contar con planes y programas nacionales de lucha contra el cancer. 'Confio en que este evento en America Latina sea el primero de muchos que nos permitan trabajar de consuno para ayudar a combatir esa terrible enfermedad y ofrecer calidad de vida a nuestros congeneres', indico el Director General del OIEA, Dr. Mohamed ElBaradei. 'El cancer es una enfermedad que se esta propagando

  15. Influencia del material de aporte en la resistencia a corrosión por picadura en uniones soldadas de un acero inoxidable dúplex 2205

    Directory of Open Access Journals (Sweden)

    Múnez, C. J.

    2007-08-01

    Full Text Available In this work, it has been studied the pitting corrosion resistance of welding duplex stainless steel 2205. Unions were made by GMAW process with different fillers: duplex ER 2209 and two austenitic (ER 316LSi and ER 308LSi. The microstructure obtained with the duplex ER 2209 filler is similar to the duplex 2205 base material, but the unions produced with the austenitic fillers cause a decrease of the phases relation a/g. To evaluate the influence of the filler on the weld, the pitting corrosion resistance was determined by electrochemical critical pitting temperature test (TCP and the mechanical properties by the hardness. The phases imbalance produced for the dissimilar fillers bring out a variation of the pitting corrosion resistance and the mechanical properties.

    En este trabajo se ha estudiado la resistencia a la corrosión localizada por picadura, de soldaduras realizadas sobre un acero inoxidable dúplex 2205. Se hicieron uniones mediante el proceso GMAW, utilizando como material de aporte un hilo dúplex ER 2209 y dos austeníticos ER 316LSi y ER 308LSi. Metalúrgicamente, se observa como para el hilo ER 2209 las microestructuras que se obtienen son similares a la del dúplex 2205, mientras que en las uniones con hilo austenítico, pueden verse microestructuras muy diferentes en las que la relación de fases a/g disminuye. Al evaluar la resistencia a la corrosión por picadura, mediante la Temperatura Crítica de Picadura (TCP, se comprobó como el desequilibrio entre las fases, generado por el aporte, provoca la variación en la resistencia a la corrosión localizada por picadura. También, se estudió la variación en las propiedades mecánicas del material mediante ensayos de dureza.

  16. Union of 99m Tc-HYNIC-TOC at the somatostatin receptors in cells of pancreas cancer

    International Nuclear Information System (INIS)

    Rodriguez C, J.; Ramirez I, M.T.; Ferro F, G.; Pedraza L, M.

    2005-01-01

    The radiation toxic effects have been used in therapy however much 50 years. The absorbed radiation dose can be determined at cellular level using cancerous cell cultures. If the deposited In vitro radiation dose coming from similar activities of several therapeutic radiopharmaceuticals it can compare it will be possible to choose the therapeutic radiopharmaceutical that it offers better dosimetric characteristics for the patient. The objective of this original investigation was to determine the union percentage of the octreotide 99m Tc-HYNlC-TOC to the somatostatin receivers in cells of cancer pancreas as well as the internalization, externalization and cellular viability. It was used the octapeptide, (octreotide, TOC) labelled with 99m Tc by means of the HYNIC chelating agent (6-hydrazine pyridine-3-carboxylic acid) and 3 cellular lines of murine pancreas cancer (AR42J), of cancer of human pancreas (CAPAN) and of one negative cellular line for somatostatin receivers (WRL-68). The 99m Tc-HYNIC-TOC was compared against two negative proofs for somatostatin receivers: the peptide 99m Tc-UBI and the 99m TcO 4 . The cellular lines were conserved in the synthetic media Dulbecco-Eagle. After 2, 4 and 24 h of exhibition to the radiation, the cells are picked up and its are determined the viability by count in a Neubauer camera using tripan blue. In the same times it was calculated the union percentage of the radiopharmaceutical to the cells and the internalization (union to the cytoplasm) and the externalization (union to membrane receivers). With those figures it was calculated the absorbed radiation dose at cellular level. Results: At 4 hours the union percentage of the 99m Tc-HYNlC-TOC to the AR42-J cells was 6.83 times greater than for the WRL-68 control cells of human papilloma, (without receivers of the somatostatin) and for the CAPAN them 4 times greater than for the same cells used as negative control, for the case of the 99m Tc-UBI and the 99m TcO 4 one doesn

  17. Unemployment, public-sector health-care spending and breast cancer mortality in the European Union: 1990-2009.

    Science.gov (United States)

    Maruthappu, Mahiben; Watkins, Johnathan A; Waqar, Mueez; Williams, Callum; Ali, Raghib; Atun, Rifat; Faiz, Omar; Zeltner, Thomas

    2015-04-01

    The global economic crisis has been associated with increased unemployment, reduced health-care spending and adverse health outcomes. Insights into the impact of economic variations on cancer mortality, however, remain limited. We used multivariate regression analysis to assess how changes in unemployment and public-sector expenditure on health care (PSEH) varied with female breast cancer mortality in the 27 European Union member states from 1990 to 2009. We then determined how the association with unemployment was modified by PSEH. Country-specific differences in infrastructure and demographic structure were controlled for, and 1-, 3-, 5- and 10-year lag analyses were conducted. Several robustness checks were also implemented. Unemployment was associated with an increase in breast cancer mortality [P unemployment rises (P unemployment and breast cancer mortality remained in all robustness checks. Rises in unemployment are associated with significant short- and long-term increases in breast cancer mortality, while increases in PSEH are associated with reductions in breast cancer mortality. Initiatives that bolster employment and maintain total health-care expenditure may help minimize increases in breast cancer mortality during economic crises. © The Author 2014. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  18. Age of diagnosis of breast cancer in china: almost 10 years earlier than in the United States and the European union.

    Science.gov (United States)

    Song, Qing-Kun; Li, Jing; Huang, Rong; Fan, Jin-Hu; Zheng, Rong-Shou; Zhang, Bao-Ning; Zhang, Bin; Tang, Zhong-Hua; Xie, Xiao-Ming; Yang, Hong-Jian; He, Jian-Jun; Li, Hui; Li, Jia-Yuan; Qiao, You-Lin; Chen, Wan-Qing

    2014-01-01

    The study aimed to describe the age distribution of breast cancer diagnosis among Chinese females for comparison with the United States and the European Union, and provide evidence for the screening target population in China. Median age was estimated from hospital databases from 7 tertiary hospitals in China. Population-based data in China, United States and European Union was extracted from the National Central Cancer Registry, SEER program and GLOBOCAN 2008, respectively. Age-standardized distribution of breast cancer at diagnosis in the 3 areas was estimated based on the World Standard Population 2000. The median age of breast cancer at diagnosis was around 50 in China, nearly 10 years earlier than United States and European Union. The diagnosis age in China did not vary between subgroups of calendar year, region and pathological characteristics. With adjustment for population structure, median age of breast cancer at diagnosis was 50~54 in China, but 55~59 in United States and European Union. The median diagnosis age of female breast cancer is much earlier in China than in the United States and the European Union pointing to racial differences in genetics and lifestyle. Screening programs should start at an earlier age for Chinese women and age disparities between Chinese and Western women warrant further studies.

  19. Propriedad intelectual en el marco del acuerdo Mercosur – Union Europea de 1995: apuntes teoricos para las negociaciones intercontinentales (1999-2002

    Directory of Open Access Journals (Sweden)

    Astrid Uzcátegui

    2002-09-01

    Full Text Available El presente artículo buscapresentar consideraciones científicas sobrela propiedad intelectual que pueden ser utilizadaspor los negociadores intercontinentalesdel Mercado Común del Sur convistas a alcanzar mejores resultados en elcomplejo proceso de negociación con laUnión Europea que resultará en la primeraZona de Libre Comercio entre dos unionesaduaneras a escala intercontinental. En estesentido, la superación de las eventualestrabas por los dos bloques regionales daráal mundo una verdadera prueba de lavalidez de un regionalismo abierto.Abstract: The present article presentsscientific considerations on intellectualproperty which may be used by intercontinentalnegotiators of the Mercosur, with theaim of accomplishing better results in thecomplex negotiation process whose resultwill be the first Free Trade Zone betweentwo customs unions in an intercontinentalscale. In this sense, overcoming eventualobstacles between these two regional blockswill offer the world a true evidence of thevalidity of an open regionalism.

  20. LAS UNIONES MARITALES DE HECHO ENTRE PAREJAS DEL MISMO SEXO, UNA LUCHA INCONCLUSA CONTRA LA DISCRIMINACIÓN

    Directory of Open Access Journals (Sweden)

    Juan Pablo Sarmiento E.

    2009-01-01

    Full Text Available A partir de la investigación realizada en las notarías de Bogotá sobre la implementación de la Sentencia C-075 de 2007 de la Corte Constitucional, que permite la declaración de unión marital de hecho entre parejas homosexuales, se argumenta que, pese al amplio margen de aplicación de esta sentencia, alguna de estas oficinas ejercen formas de violencia simbólica y discriminación y rechazan de las parejas que intentan realizar dicho trámite. Ello permite constatar que las uniones maritales de hecho están lejos de construir un espacio que atenúa la discriminación contra la diversidad sexual.

  1. Genetic modifiers of CHEK2*1100delC-associated breast cancer risk

    DEFF Research Database (Denmark)

    Muranen, Taru A; Greco, Dario; Blomqvist, Carl

    2017-01-01

    PURPOSE: CHEK2*1100delC is a founder variant in European populations that confers a two- to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk associated with CHEK2*1100delC is modified by other genetic factors in a multiplicative fashion....... We have investigated this empirically using data from the Breast Cancer Association Consortium (BCAC). METHODS: Using genotype data from 39,139 (624 1100delC carriers) BC patients and 40,063 (224) healthy controls from 32 BCAC studies, we analyzed the combined risk effects of CHEK2*1100delC and 77...

  2. Excess breast cancer risk in first degree relatives of CHEK2∗1100delC positive familial breast cancer cases

    NARCIS (Netherlands)

    Adank, Muriel A.; Verhoef, Senno; Oldenburg, Rogier A.; Schmidt, Marjanka K.; Hooning, Maartje J.; Martens, John W. M.; Broeks, Annegien; Rookus, Matti; Waisfisz, Quinten; Witte, Birgit I.; Jonker, Marianne A.; Meijers-Heijboer, Hanne

    2013-01-01

    The CHEK2∗1100delC mutation confers a relative risk of two for breast cancer (BC) in the general population. This study aims to explore the excess cancer risk due to the CHEK2∗1100delC mutation within a familial non-BRCA1/2 breast cancer setting. Cancer incidences were compared between first degree

  3. Del-1 Expression as a Potential Biomarker in Triple-Negative Early Breast Cancer.

    Science.gov (United States)

    Lee, Soo Jung; Lee, Jeeyeon; Kim, Wan Wook; Jung, Jin Hyang; Park, Ho Yong; Park, Ji-Young; Chae, Yee Soo

    2018-01-01

    A differential diagnostic role for plasma Del-1 was proposed for early breast cancer (EBC) in our previous study. We examined tumoral Del-1 expression and analyzed its prognostic impact among patients with EBC. Del-1 mRNA expression was assessed in breast epithelial and cancer cells. Meanwhile, the tumoral expression of Del-1 was determined based on tissue microarrays and immunohistochemistry results from 440 patients. While a high Del-1 mRNA expression was found in all the breast cancer cell lines, the expression was significantly higher in MDA-MB-231. Tumoral expression of Del-1 was also significantly associated with a negative expression of estrogen receptor or progesterone receptor, and low expression of Ki-67, particularly in the case of triple-negative breast cancer (TNBC) (p breast cancer cell lines exhibited Del-1 expression, the expression rate and intensity were specifically prominent in TNBC. In addition, based on its relationship to an unfavorable histology and worse survival trend, Del-1 could act as a molecular target in TNBC patients. © 2018 S. Karger AG, Basel.

  4. Análisis del comportamiento elasto-plástico de grietas internas presurizadas en uniones soldadas de tubos de acero bajo carbono

    Directory of Open Access Journals (Sweden)

    Martín Julián Fernández Cueto

    2011-01-01

    Full Text Available Se analizó el comportamiento elasto-plástico de áreas con grietas internas planas presurizadas. El análisis se efectuó desde el metal base (uniones soldadas de tubos de acero bajo carbono sometidos a presión interna pasando por la zona afectada por el calor hasta el metal depositado. Se usó el programa comercial ANSYS 8.0 [MR] para la simulación en tres dimensiones de modelos geométricos de tubos con grietas internas presurizadas. Se consideró el endurecimiento cinemático y las propiedades reales del material para cada región, mediante elementos finitos con condiciones no lineales de deformación. Se determinaron las trayectorias de fractura y se obtuvieron expresiones que permiten calcular la presión en la grieta y en el tubo. Esto conduce a la fractura de la zona agrietada.

  5. Muertes silenciadas: Problemática del suicidio en los campesinos de La Unión (Antioquia / Silenced Kills: Problems of farmers suicide in La Union, Antioquia

    Directory of Open Access Journals (Sweden)

    Andrea L. Pérez

    2014-05-01

    Full Text Available Durante las últimas dos décadas se han incrementado notoriamente las tasas de suicidio en la población campesina colombiana. Objetivo: explicar los componentes sociales que contribuyen a la configuración de conductas suicidas recurrentes en ciertas poblaciones rurales a través de un estudio de caso del municipio de La Unión (Antioquia, cuyas tasas de suicidio han sido bastante elevadas durante ese período, encima de 20 sobre cien mil habitantes, mientras las tasas nacionales oscilan entre 4 y 5. Metodología: se utilizaron estrategias metodológicas cualitativas y cuantitativas a fin de realizar lecturas integrales de la problemática (datos estadísticos del suicidio en los años 1990-2000, encuestas, entrevistas y etnografía. Se privilegia el análisis sociológico, de entender el suicidio como fenómeno colectivo que depende de ciertas condiciones sociales y apropiaciones subjetivas. Resultados y discusión: se obtuvieron las siguientes dimensiones sociales que caracterizan el fenómeno estudiado: (a intensificación del modelo neoliberal que devastó la economía campesina local; (b agudización del conflicto armado que desestructuró la vida social; (c vulnerabilidad de los jóvenes campesinos, mayores receptores de las carencias del campo; (d subjetividades de género que inciden en la conducta suicida de manera inversa: más hombres que se suicidan por más mujeres que lo intenta Over the last two decades the problem of suicide among the Colombian peasant farmer population has seen a marked increase. Objective: to explain the social components that contribute to recurring suicidal behavior in certain rural populations though a case study of the La Union (Antioquia municipality, the suicide rates of which have been evidently higher during this period at over 20 in every thousand inhabitants, while the national rate fluctuates between 4 and 5. Methodology: quantitative and qualitative methodological strategies were used with the aim

  6. European Union

    International Nuclear Information System (INIS)

    Schaller, K.

    1995-01-01

    Different instruments used by European Commission of the European Union for financial support radioactive waste management activities in the Russian Federation are outlined. Three particular programmes in the area are described

  7. The single non-representative trade union as a political and economic instrument of the Franco Regime | El sindicato vertical como instrumento político y económico del régimen franquista

    Directory of Open Access Journals (Sweden)

    Glicerio Sánchez Recio

    2002-12-01

    Full Text Available The single non-representative trade union followed the pattern of the single party in order to carry out the function specified in the title of this article. With compulsory membership for all workers and employers, the single trade union was deployed by the Franco regime in order to bring both sides of industry together. An analysis of its history shows that it was a political and economic instrument of the regime. The regime gave the union its powers and solved the conflicts that arose, while at the same time using it to control and contain the workers, and pay back owners and managers for their support. | El sindicato único y vertical fue el instrumento parejo del partido único para ejercer la función que se le atribuye en el título. A través del sindicato único, de afiliación generalizada y obligatoria para obreros y empresarios, el franquismo trataba de integrar al mundo del trabajo y de la empresa. A través del análisis de su trayectoria puede afirmarse que el sindicato vertical fue un instrumento político y económico del régimen franquista, que fue éste el que le dio la fuerza y resolvió los problemas que se le plantearon, pero que, al mismo tiempo, lo utilizó para controlar y encuadrar a los obreros y compensar a los empresarios y patronos por los apoyos que le prestaban.

  8. Union for International Cancer Control International Session: healthcare economics: the significance of the UN Summit non-communicable diseases political declaration in Asia.

    Science.gov (United States)

    Akaza, Hideyuki; Kawahara, Norie; Masui, Tohru; Takeyama, Kunihiko; Nogimori, Masafumi; Roh, Jae Kyung

    2013-06-01

    The Japan National Committee for the Union for International Cancer Control (UICC) and UICC-Asia Regional Office (ARO) organized an international session as part of the official program of the 71st Annual Meeting of the Japanese Cancer Association to discuss the topic "Healthcare Economics: The Significance of the UN Summit non-communicable diseases (NCDs) Political Declaration in Asia." The presenters and participants discussed the growing cost of cancer in the Asian region and the challenges that are faced by the countries of Asia, all of which face budgetary and other systemic constraints in tackling and controlling cancer in the region. The session benefited from the participation of various stakeholders, including cancer researchers and representatives of the pharmaceutical industry. They discussed the significance of the UN Political Declaration on the prevention and control of NCDs (2011) as a means of boosting awareness of cancer in the Asian region and also addressed the ways in which stakeholders can cooperate to improve cancer control and treatment. Other issues that were covered included challenges relating to pharmaceutical trials in Asia and how to link knowledge and research outcomes. The session concluded with the recognition that with the onset of a super-aged society in most countries in Asia and an increasing focus on quality of life rather than quantity of life, it is more important than ever for all stakeholders to continue to share information and promote policy dialogue on cancer control and treatment. © 2013 Japanese Cancer Association.

  9. Influencia del precalentamiento en las propiedades de uniones soldadas de acero API 5L-X80 soldadas con alambre tubular autoprotegido

    Directory of Open Access Journals (Sweden)

    Cooper, R.

    2004-08-01

    Full Text Available The present work refers to the characterization of API 5L-X80 pipeline joints welded with self-shielded flux cored wire. This process was evaluated under preheating conditions, with an uniform and steady heat input. All joints were welded in flat position (IG, with the pipe turning and the torch still. Tube dimensions were 762 mm in external diameter and 16 mm in thickness. Welds were applied on single V-groove, with six weld beads, along with three levels of preheating temperatures (room temperature, 100 °C, 160 °C. These temperatures were maintained as interpass temperature. The filler metal E71T8-K6 with mechanical properties different from parent metal was used in undermatched conditions. The weld characterization is presented according to the mechanical test results of tensile strength, hardness and impact test. The mechanical tests were conducted according to API 1104, AWS and ASTM standards. API 1104 and API 51 were used as screening criteria. According to the results obtained, it was possible to remark that it is appropriate to weld API 5L-X80 steel ducts with Self-shielded Flux Cored wires, in conformance to the API standards and no preheat temperature is necessary.

    Este trabajo presenta un estudio sobre la caracterización de las propiedades mecánicas de uniones soldadas con alambre tubular autoprotegido, de acero API 5L-X80. En este sentido, se evalúa la influencia de la temperatura de precalentamiento, manteniendo el aporte de calor uniforme. Todas las uniones soldadas se realizaron en la posición plana (IG, con la antorcha fíja y la tubería girando. Se utilizó un tubo de 762 mm de diámetro exterior y 16 mm de espesor. Las soldaduras se aplicaron sobre una unión de tope con bisel en V simple, utilizando 6 pasadas, con tres niveles de temperatura de precalentamiento (ambiente, 100 °C y 160 °C. Estas temperaturas se mantuvieron como temperatura entre pasadas. El metal de aporte, del tipo E71T8-K6, se utilizó en la

  10. IARC Report to the Union for International Cancer Control (UICC) on the Interphone Study

    International Nuclear Information System (INIS)

    Wild, Christopher

    2011-01-01

    Mobile phone use has increased dramatically in many countries since its introduction in the early-to-mid 1980's. The expanding use of this technology has been accompanied by concerns about health and safety. In the late 1990's, several expert groups critically reviewed the evidence on health effects of low-level exposure to radiofrequency (RF) electromagnetic fields emitted by mobile phones, and recommended research into the possible adverse health effects of mobile telephone use. As a result, the International Agency for Research on Cancer (IARC) coordinated a feasibility study in 1998 and 1999, which concluded that an international study of the relationship between mobile phone use and brain tumour risk would be feasible and informative. Interphone was therefore initiated as an international set of case-control studies focussing on four types of tumours in tissues that most absorb RF energy emitted by mobile phones: tumours of the brain (glioma and meningioma), acoustic nerve (schwannoma) and parotid gland. The objective was to determine whether mobile phone use increases the risk of these tumours and, specifically, whether RF energy emitted by mobile phones is carcinogenic. The methods, results and conclusions are provided here and thus this report to the UICC marks the completion of the Interphone Study. A major strength of the Interphone study was the conduct of several validation studies to assist in assessing the study's strengths and limitations and inform the researchers about possible shortcomings when interpreting the main results. In this context Interphone is quite unique among epidemiological studies on health effects of mobile phone use and the insight obtained from the validation studies is also informative when it comes to evaluating other studies in this field. The comprehensive validation studies are a unique feature of Interphone, enabling the researchers to quantify problems persistent in this type of observational studies and to assist in the

  11. CHEK2∗1100delC Mutation and Risk of Prostate Cancer

    Directory of Open Access Journals (Sweden)

    Victoria Hale

    2014-01-01

    Full Text Available Although the causes of prostate cancer are largely unknown, previous studies support the role of genetic factors in the development of prostate cancer. CHEK2 plays a critical role in DNA replication by responding to double-stranded breaks. In this review, we provide an overview of the current knowledge of the role of a genetic variant, 1100delC, of CHEK2 on prostate cancer risk and discuss the implication for potential translation of this knowledge into clinical practice. Currently, twelve articles that discussed CHEK2∗1100delC and its association with prostate cancer were identified. Of the twelve prostate cancer studies, five studies had independent data to draw conclusive evidence from. The pooled results of OR and 95% CI were 1.98 (1.23–3.18 for unselected cases and 3.39 (1.78–6.47 for familial cases, indicating that CHEK2∗1100delC mutation is associated with increased risk of prostate cancer. Screening for CHEK2∗1100delC should be considered in men with a familial history of prostate cancer.

  12. CHEK2 c.1100delC allele is rarely identified in Greek breast cancer cases.

    Science.gov (United States)

    Apostolou, Paraskevi; Fostira, Florentia; Papamentzelopoulou, Myrto; Michelli, Maria; Panopoulos, Christos; Fountzilas, George; Konstantopoulou, Irene; Voutsinas, Gerassimos E; Yannoukakos, Drakoulis

    2015-04-01

    The CHEK2 gene encodes a protein kinase that plays a crucial role in maintenance of genomic integrity and the DNA repair mechanism. CHEK2 germline mutations are associated with increased risk of breast cancer and other malignancies. From a clinical perspective, the most significant mutation identified is the c.1100delC mutation, which is associated with an approximately 25% lifetime breast cancer risk. The distribution of this mutation shows wide geographical variation; it is more prevalent in the Northern European countries and less common, or even absent, in Southern Europe. In order to estimate the frequency of the CHEK2 c.1100delC mutation in Greek breast cancer patients, we genotyped 2,449 patients (2,408 females and 41 males), which was the largest series ever tested for c.1100delC. The mean age of female and male breast cancer diagnosis was 49 and 59 years, respectively. All patients had previously tested negative for the Greek BRCA1 founder and recurrent mutations. The CHEK2 c.1100delC mutation was detected in 0.16% (4 of 2,408) of females, all of whom were diagnosed with breast cancer before the age of 50 years. Only one c.1100delC carrier was reported with breast cancer family history. The present study indicates that the CHEK2 c.1100delC mutation does not contribute substantially to hereditary breast cancer in patients of Greek descent. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Status of implementation and organization of cancer screening in The European Union Member States-Summary results from the second European screening report.

    Science.gov (United States)

    Basu, Partha; Ponti, Antonio; Anttila, Ahti; Ronco, Guglielmo; Senore, Carlo; Vale, Diama Bhadra; Segnan, Nereo; Tomatis, Mariano; Soerjomataram, Isabelle; Primic Žakelj, Maja; Dillner, Joakim; Elfström, Klara Miriam; Lönnberg, Stefan; Sankaranarayanan, Rengaswamy

    2018-01-01

    The second report on the implementation status of cancer screening in European Union (EU) was published in 2017. The report described the implementation status, protocols and organization (updated till 2016) and invitation coverage (for index year 2013) of breast, cervical and colorectal cancer screening in the EU. Experts in screening programme monitoring (N = 80) from the EU Member States having access to requisite information in their respective countries provided data on breast, cervical and colorectal cancer screening through online questionnaires. Data was collected for screening performed in the framework of publicly mandated programmes only. Filled in questionnaires were received from 26 Member States for all three sites and from one Member State for breast cancer only. Substantial improvement in screening implementation using population-based approach was documented. Among the age-eligible women, 94.7% were residents of Member States implementing or planning population-based breast cancer screening in 2016, compared to 91.6% in 2007. The corresponding figures for cervical cancer screening were 72.3 and 51.3% in 2016 and 2007, respectively. Most significant improvement was documented for colorectal cancer screening with roll-out ongoing or completed in 17 Member States in 2016, compared to only five in 2007. So the access to population-based screening increased to 72.4% of the age-eligible populations in 2016 as opposed to only 42.6% in 2007. The invitation coverage was highly variable, ranging from 0.2-111% for breast cancer, 7.6-105% for cervical cancer and 1.8-127% for colorectal cancer in the target populations. In spite of the considerable progress, much work remains to be done to achieve optimal effectiveness. Continued monitoring, regular feedbacks and periodic reporting are needed to ensure the desired impacts of the programmes. © 2017 UICC.

  14. Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers

    DEFF Research Database (Denmark)

    Schmidt, Marjanka K; Hogervorst, Frans; van Hien, Richard R

    2016-01-01

    PURPOSE: CHEK2*1100delC is a well-established breast cancer risk variant that is most prevalent in European populations; however, there are limited data on risk of breast cancer by age and tumor subtype, which limits its usefulness in breast cancer risk prediction. We aimed to generate tumor...... subtype- and age-specific risk estimates by using data from the Breast Cancer Association Consortium, including 44,777 patients with breast cancer and 42,997 controls from 33 studies genotyped for CHEK2*1100delC. PATIENTS AND METHODS: CHEK2*1100delC genotyping was mostly done by a custom Taqman assay....... Breast cancer odds ratios (ORs) for CHEK2*1100delC carriers versus noncarriers were estimated by using logistic regression and adjusted for study (categorical) and age. Main analyses included patients with invasive breast cancer from population- and hospital-based studies. RESULTS: Proportions...

  15. Avances en el diagnostico ecografico del cancer de prostate

    NARCIS (Netherlands)

    Laguna, M.P.; Wondergem, N.; Wink, M.H.; Wijkstra, H.; Rosette, de la J.J.M.C.H.

    2010-01-01

    OBJETIVO: La biopsia guiada por ecografía posee un papel primordial en el diagnóstico del cáncer de próstata. Diversos protocolos de biopsia prostática guiada mediante ultrasonidos se han diseño en un intento de mejorar el diagnóstico del cáncer de próstata. La incorporación de los contrastes

  16. MDM2 promoter del1518 polymorphism and cancer risk: evidence from 22,931 subjects

    Directory of Open Access Journals (Sweden)

    Hua WF

    2017-07-01

    Full Text Available Wenfeng Hua,1,* Anqi Zhang,2,* Ping Duan,2,* Jinhong Zhu,3 Yuan Zhao,2 Jing He,4 Zhi Zhang1 1Department of Laboratory Medicine and Central Laboratories, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, 2Department of Obstetrics and Gynecology, The Second Affiliated Hospital & Yuying Children’s Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 3Molecular Epidemiology Laboratory and Department of Laboratory Medicine, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, 4Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China *These authors contributed equally to this work Abstract: Studies have shown that single-nucleotide polymorphisms in MDM2 gene may play important roles in the development of malignant tumor. The association of del1518 polymorphism (rs3730485 in the MDM2 promoter with cancer susceptibility has been extensively studied; however, the results are contradictory. To quantify the association between this polymorphism and overall cancer risk, we conducted a meta-analysis with 12,905 cases and 10,026 controls from 16 eligible studies retrieved from PubMed, Embase, and Chinese Biomedical (CBM databases. We assessed the strength of the connection using odds ratios (ORs and 95% confidence intervals (CIs. In summary, no significant associations were discovered between the del1518 polymorphism and overall cancer risk (Del/Del vs Ins/Ins: OR =1.01, 95% CI =0.90–1.14; Ins/Del vs Ins/Ins: OR =1.03, 95% CI =0.96–1.12; recessive model: OR =0.98, 95% CI =0.90–1.07; dominant model: OR =1.03, 95% CI =0.94–1.12; and Del vs Ins: OR =1.01, 95% CI =0.94–1.07. In the stratified analysis by source of control, quality score, cancer type, and ethnicity, no significant associations were found. Despite some limitations, the current meta-analysis provides solid

  17. The CHEK2 del5395 is a founder mutation without direct effects for cancer risk in the latvian population

    Directory of Open Access Journals (Sweden)

    Plonis J

    2015-12-01

    Full Text Available Our objective was to determine: 1 whether the checkpoint kinase 2 (CHEK2 del5395 (g.27417113-27422508 del, NC_000022.11 is a founder mutation in the Latvian population, 2 if there is an association between CHEK2 del5395 mutation and cancer risk, and 3 and whether the CHEK2 del5395 mutation impacts cancer predisposition in Chernobyl disaster liquidators (the civil and military personnel who were called upon to deal with consequences of the 1986 nuclear disaster as well as geriatric populations. We recruited 438 breast cancer patients, 568 colorectal cancer patients, 399 ovarian cancer patients, 419 prostate cancer patients, 526 healthy blood donors, 480 Chernobyl disaster liquidators and 444 geriatric cancer-free participants. DNA samples were isolated from blood samples and subjected to multiplex polymerase chain reaction (PCR. The truncation of del5395 was estimated by fragment size of the multiplex PCR.All groups were compared to the healthy blood donors using Fisher’s exact test. All p values were two-sided and the odds ratios (OR calculated by two-by-two table. In cancer groups, the del5395 mutation was most frequently observed in the ovarian cancer group (1.00%, OR = 1.32. In control groups, the del5395 mutation was most frequent (0.76% in the healthy donors, which exceeded its frequency in the Chernobyl liquidators group and the geriatric group by 0.01 and 0.08%, respectively. For all groups, the OR appeared to be >1 only in ovarian cancer patients. However, OR rates showed no statistical significance in either cancer or control groups, with the p value fluctuating within the range of 0.39-1.00. The CHEK2 gene del5395 is a founder mutation in the Latvian population, which, however, does not have a direct impact on genetic predisposition toward colorectal, breast, ovarian and prostate cancer.

  18. Impact of the new international association for the study of lung cancer staging system in non-small cell lung cancer: With comparison to the union for international cancer control 6th tumor, node, metastasis edition

    International Nuclear Information System (INIS)

    Lee, Myung Jae; Lee, So Won; Shim, Sung Shine; Ryu, Yon Ju; Kim, Yoo Kyung

    2014-01-01

    To investigate the impact of the proposed International Association for the Study of Lung Cancer (IASLC) tumor, node, metastasis (TNM) system on staging and outcome of non small cell lung cancer (NSCLC). With a total of 501 NSCLC patients with staging according to Union for International Cancer Control (UICC), 6th TNM (TNM-6) were reclassified according to the IASLC proposed TNM staging (TNM-7). The impact of TNM-7 in comparison with TNM-6 was evaluated at three levels: change in substage, staging, and outcome. The outcome measure was to compare the stage-specific overall survival of NSCLC between the two groups of patients. A total of 214 (42.7%) patients had changed TNM staging, and 101 (20.2%) patients had changed stage groupings in TNM-7 compared to TNM-6. Among 100 patients showing changed stage grouping, 72 (14.4%) showed upstage and 29 (5.8%) demonstrated downstage. The TNM-7 system resulted in better separation of survival curves among stage-specific NSCLC than TNM-6 system, especially in separation of stage IIA vs. IIB (p 0.023) and stage IIIB vs. IV (p < 0.001). TNM-7 for lung cancer appears to be superior in defining stage-specific survival groups than TNM-6, especially between stage IIA vs. stage IIB and stage IIIB vs. stage IV.

  19. Importancia del Programa de Deteccion Temprana del cancer bucal en Cuba

    OpenAIRE

    Morales Navarro, Denia; Rodríguez Lay, Liliana; García Jordán, Mariela

    2009-01-01

    El cáncer es un factor importante de la carga mundial de morbilidad, y lo será cada vez más en los decenios venideros. El aumento global del número de casos de cáncer bucal y la factibilidad de realizar acciones de salud específicas nos motivó a consultar la bibliografía que maneja este tema e indagar sobre los resultados del Programa de Detección del Cáncer Bucal en Cuba. Se realizó una revisión bibliográfica mediante la consulta de bases de datos de los sistemas referativos, como MEDLINE y ...

  20. CHEK2 (∗) 1100delC Mutation and Risk of Prostate Cancer

    DEFF Research Database (Denmark)

    Hale, Victoria; Weischer, Maren; Park, Jong Y

    2014-01-01

    Although the causes of prostate cancer are largely unknown, previous studies support the role of genetic factors in the development of prostate cancer. CHEK2 plays a critical role in DNA replication by responding to double-stranded breaks. In this review, we provide an overview of the current...... knowledge of the role of a genetic variant, 1100delC, of CHEK2 on prostate cancer risk and discuss the implication for potential translation of this knowledge into clinical practice. Currently, twelve articles that discussed CHEK2 (∗)1100delC and its association with prostate cancer were identified....... Of the twelve prostate cancer studies, five studies had independent data to draw conclusive evidence from. The pooled results of OR and 95% CI were 1.98 (1.23-3.18) for unselected cases and 3.39 (1.78-6.47) for familial cases, indicating that CHEK2 (∗)1100delC mutation is associated with increased risk...

  1. CHEK2*1100delC Heterozygosity in Women With Breast Cancer Associated With Early Death, Breast Cancer-Specific Death, and Increased Risk of a Second Breast Cancer

    DEFF Research Database (Denmark)

    Weischer, Maren; Nordestgaard, Børge G; Pharoah, Paul

    2012-01-01

    PURPOSE We tested the hypotheses that CHEK2*1100delC heterozygosity is associated with increased risk of early death, breast cancer-specific death, and risk of a second breast cancer in women with a first breast cancer. PATIENTS AND METHODS From 22 studies participating in the Breast Cancer Assoc...

  2. CHEK2 1100delC and polygenic susceptibility to breast cancer and colorectal cancer

    NARCIS (Netherlands)

    M. Wasielewski (Marijke)

    2009-01-01

    textabstractApproximately 15-25% of breast cancers are identified in women with a family history of breast cancer. Yet, germline mutations in the currently known breast cancer susceptibility genes account for only one-third of familial breast cancer cases. In 2002, our research group had identified

  3. RASTREO DEL CANCER COLORRECTAL CONOCIMIENTO Y ACTITUD DE LA POBLACION

    Science.gov (United States)

    CASAL, ENRIQUE R.; VELAZQUEZ, ELIZABETH N.; MEJIA, RAUL M.; CUNEO, ALDO; PEREZ-STABLE, ELISEO J.

    2014-01-01

    Resumen El rastreo de cáncer colorrectal (CCR) cuenta con fuertes evidencias en su favor. Datos preliminares indican que a pesar de ello no se lleva a cabo con la frecuencia adecuada. Se intenta aquí determinar, dentro de un Sistema de Salud que cuenta con los recursos necesarios, los elementos que facilitan o generan barreras para concretar esta práctica preventiva, cuántos individuos lo ponen en práctica y qué predice esta conducta. Se realizó una encuesta telefónica a los afiliados de una Obra Social de empleados de la Universidad de Buenos Aires, de los que 132 completaron el cuestionario (tasa de respuesta 70%). Los elementos considerados facilitadores del rastreo obtuvieron respuestas afirmativas en el 64 a 97%, mientras que los que definían barreras un 11 a 27%. En este último grupo, una categoría diferenciada la constituía el miedo a los efectos adversos: 39%, y el sentimiento de vergüenza relacionado con los procedimientos: 30%. Un 33% de los encuestados tenían hecho un método de rastreo, mayoritariamente de sangre oculta (27), sigmoideoscopía (11) y colonoscopía (20). Una mayoría afirmó que “se haría el procedimiento si el médico se lo recomendara” (95%), o “no se lo haría excepto que su médico se lo aconseje” (87%). Contestar afirmativamente que “los médicos hacen lo mejor para los pacientes” se asoció con haberse hecho un método de rastreo de CCR, OR 1.55 (IC 95%: 1.02-2.37) p: 0.04. El grupo de individuos estudiado parece bien predispuesto para el rastreo del CCR, la recomendación médica sería aquí un determinante prominente para ponerlo en práctica. PMID:19414294

  4. Going up or coming down? The changing phases of the lung cancer epidemic from 1967 to 1999 in the 15 European Union countries.

    Science.gov (United States)

    Bray, F; Tyczynski, J E; Parkin, D M

    2004-01-01

    Lung cancer, the most common cause of cancer death in the European Union (EU), continues to have an enormous impact on the health experience of the men and women living in the constituent countries. Information on the course of the lung cancer epidemic is essential in order to formulate an effective cancer control policy. This paper examines recent trends in lung cancer mortality rates in men and women in each of the 15 countries, comparing cross-sectional rates of death in younger (aged 30-64 years) and older populations (aged 65 years or over), and the age, period of death, and birth cohort influences in the younger age group. The latter analysis establishes the importance of year of birth, related to modifications in the tobacco habit among recently born generations. The stage of evolution of the lung cancer epidemic varies markedly by sex and country in terms of the direction, magnitude, and phase of development of national trends. In males, there is some consistency in the direction of the trends between EU countries, declines are apparent in most countries, at least in younger men, with rates in older men either reaching a plateau, or also falling. In younger persons, a decreasing risk of lung cancer death reflects changes in successive birth cohorts, due to modifications in the smoking habit from generation to generation, although these developments are in very different phases across countries. Portugal is the exception to the male trends; there are increases in mortality in both age groups, with little sign of a slowing down by birth cohort. In women, there are unambiguous upsurges in rates seen in younger and older women in almost all EU countries in recent decades, and little sign that the epidemic has or will soon reach a peak. The exceptions are the United Kingdom (UK) and Ireland, where lung cancer death rates are now declining in younger women and stabilising in older women, reflecting a declining risk in women born since about 1950. It is too early

  5. Unemployment, public-sector healthcare expenditure and colorectal cancer mortality in the European Union: 1990-2009.

    Science.gov (United States)

    Maruthappu, Mahiben; Watson, Robert A; Watkins, Johnathan; Williams, Callum; Zeltner, Thomas; Faiz, Omar; Ali, Raghib; Atun, Rifat

    2016-01-01

    We examined the association between unemployment and government spending on healthcare with colorectal cancer mortality. Retrospective observational study using data from the World Bank and WHO. Multivariate regression analysis was used, controlling for country-specific differences in infrastructure and demographics. A 1 % increase in unemployment was associated with a significant increase in colorectal cancer mortality in both men and women [men: coefficient (R) = 0.0995, 95 % confidence interval (CI) 0.0132-0.1858, P = 0.024; women: R = 0.0742, 95 % CI 0.0160-0.1324, P = 0.013]. A 1 % increase in government spending on healthcare was associated with a statistically significant decrease in colorectal cancer mortality across both sexes (men: R = -0.4307, 95 % CI -0.6057 to -0.2557, P < 0.001; women: R = -0.2162, 95 % CI -0.3407 to -0.0917, P = 0.001). The largest changes in mortality occurred 3-4 years following changes in either economic variable. Unemployment rises are associated with a significant increase in colorectal cancer mortality, whilst government healthcare spending rises are associated with falling mortality. This is likely due, in part, to reduced access to healthcare services and has major implications for clinicians and policy makers alike.

  6. Mortalidad por cáncer en los mineros del mercurio Cancer mortality in mercury miners

    Directory of Open Access Journals (Sweden)

    Montserrat García Gómez

    2007-06-01

    Full Text Available Objetivos: Analizar la mortalidad por cáncer en una cohorte de mineros del mercurio. Métodos: Estudiamos la mortalidad por cáncer de 3.998 mineros expuestos a mercurio de Minas de Almadén y Arrayanes, S.A. El período de seguimiento comprendió desde 1895 hasta 1994. Se determinó el estado vital y la causa básica de defunción. Se calcularon las razones de mortalidad estandarizadas (RME según la edad, el sexo y el período de calendario. Las muertes esperadas se obtuvieron de las tasas específicas españolas. Resultados: Se determinó el estado vital del 92% de los trabajadores: 1.786 estaban vivos en 1994 (49%, 1.535 habían muerto (42% y de 327 no pudo conocerse el estado vital (8%. La mortalidad por cáncer fue significativamente menor de la esperada (RME de 0,72; intervalo de confianza del 95%, 0,63-0,82, y se encontró el déficit principalmente en los cánceres de colon y vejiga. Se encontró un pequeño exceso en la mortalidad por cáncer de hígado, para el que se registraron 20 muertes, mientras se esperaban 17. La mortalidad por cáncer de pulmón y del sistema nervioso central fue prácticamente igual a la esperada; la mortalidad por cáncer de riñón fue menor de la esperada. Se observó una tendencia positiva en la mortalidad por todos los tipos de cáncer con la duración de la exposición. Conclusiones: Esta investigación aporta evidencias adicionales de la ausencia de un aumento sustancial del riesgo de cáncer en los trabajadores expuestos al mercurio inorgánico.Objectives: To analyze cancer mortality in a cohort of mercury miners. Methods: Cancer mortality in 3,998 workers exposed to mercury in Minas de Almadén y Arrayanes S.A. was studied. The follow-up period was from 1895 to 1994. Vital status and the basic cause of death, in the case of fatalities, were determined. Standardized mortality ratios (SMR by age, sex and calendar period were calculated. Expected deaths were obtained from age, sex and calendar period

  7. Comparison of the Seventh and Eighth Editions of the American Joint Committee on Cancer/Union for International Cancer Control Tumor-Node-Metastasis Staging System for Differentiated Thyroid Cancer.

    Science.gov (United States)

    Kim, Mijin; Kim, Won Gu; Oh, Hye-Seon; Park, Suyeon; Kwon, Hyemi; Song, Dong Eun; Kim, Tae Yong; Shong, Young Kee; Kim, Won Bae; Sung, Tae-Yon; Jeon, Min Ji

    2017-09-01

    To evaluate the efficacy and prognostic validity for disease-specific survival (DSS) of the eighth edition American Joint Committee on Cancer/Union for International Cancer Control tumor-node-metastasis (TNM) staging system (TNM-8) compared to the seventh edition (TNM-7) in patients with differentiated thyroid carcinoma (DTC). The seventh and eighth editions of the TNM staging system were applied to 1613 DTC patients who underwent thyroid surgery between 1996 and 2003. The proportion of variation explained and Harrell's c-index were evaluated to compare the predictive capability of DSS. The mean age of the patients was 44.7 years, and the median follow-up period was 11.2 years. When TNM-8 was applied, 63% of T3 and 3% of N1b DTCs were downgraded to T1/T2 and N1a, respectively. About 38% of patients were downstaged according to TNM-8. The 10-year DSS rates in TNM-7 stages I, II, III, and IV were 99.7%, 98.2%, 98.8%, and 83.2%, respectively. Those in TNM-8 stages I, II, III, and IV were 99.6%, 95.4%, 72.3%, and 48.6%, respectively. The proportion of variation explained values of TNM-7 and TNM-8 were 6.0% and 7.0%, respectively. The Harrell's c-index of TNM-7 was 0.86 and that of TNM-8 was 0.88. A significant number of patients were reclassified to lower stages with the application of TNM-8 compared to TNM-7. Applying TNM-8 could improve the accuracy of the staging system for predicting DSS in patients with DTC.

  8. Bladder cancer exosomes contain EDIL-3/Del1 and facilitate cancer progression.

    Science.gov (United States)

    Beckham, Carla J; Olsen, Jayme; Yin, Peng-Nien; Wu, Chia-Hao; Ting, Huei-Ju; Hagen, Fred K; Scosyrev, Emelian; Messing, Edward M; Lee, Yi-Fen

    2014-08-01

    High grade bladder cancer is an extremely aggressive malignancy associated with high rates of morbidity and mortality. Understanding how exosomes may affect bladder cancer progression could reveal novel therapeutic targets. Exosomes derived from human bladder cancer cell lines and the urine of patients with high grade bladder cancer were assessed for the ability to promote cancer progression in standard assays. Exosomes purified from the high grade bladder cancer cell line TCC-SUP and the nonmalignant urothelial cell line SV-HUC were submitted for mass spectrometry analysis. EDIL-3 was identified and selected for further analysis. Western blot was done to determine EDIL-3 levels in urinary exosomes from patients with high grade bladder cancer. shRNA gene knockdown and recombinant EDIL-3 were applied to study EDIL-3 function. Exosomes isolated from high grade bladder cancer cells and the urine of patients with high grade bladder cancer promoted angiogenesis and migration of bladder cancer cells and endothelial cells. We silenced EDIL-3 expression and found that shEDIL-3 exosomes did not facilitate angiogenesis, and urothelial and endothelial cell migration. Moreover, exosomes purified from the urine of patients with high grade bladder cancer contained significantly higher EDIL-3 levels than exosomes from the urine of healthy controls. EDIL-3 activated epidermal growth factor receptor signaling while blockade of epidermal growth factor receptor signaling abrogated this EDIL-3 induced bladder cell migration. Exosomes derived from the urine of patients with bladder cancer contains bioactive molecules such as EDIL-3. Identifying these components and their associated oncogenic pathways could lead to novel therapeutic targets and treatment strategies. Copyright © 2014 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  9. Clinical verification of the superiority of the current International Union Against Cancer staging criteria in an Australian population of patients with nasopharyngeal carcinoma

    International Nuclear Information System (INIS)

    Corry, J.; Porceddu, S.; Peters, L.J.; Fisher, R.; Rischin, D.

    2004-01-01

    The purpose of this study is to assess the prognostic abilities of the fourth and fifth edition International Union Against Cancer (UICC) staging systems for nasopharyngeal carcinoma (NPC) in Australian patients. All patients planned for curative treatment at the Peter MacCallum Cancer Centre from April 1985 to December 1999 were included in this study. There were 181 patients eligible for this study. The median follow up was 7.6 years. Histological subgroups were World Health Organization (WHO) 1 (23), WHO 2 (12), and WHO 3 (146). Presentation with stage IV disease was 83% by UICC fourth edition staging and 34% by UICC fifth edition staging. The 5 years failure-free survival (FFS) rates for stage 1, 2, 3 and 4 disease by the fourth edition was 77, 100, 93, and 49% respectively,and by the fifth edition was 85, 76. 57 and 36%, respectively. The 5 years overall survival (OS) for stage 1, 2, 3, and 4 disease by the fourth edition was 77. 100, 100 and 61%; respectively.and by the fifth edition was 85, 82, 67 and 53%, respectively. Stage 4 patients by the fourth edition were reclassified as stages 2, 3 and 4 by the fifth edition with hazard ratios of 0.77, 1.01 and 1.79, respectively. In multifactor analysis, the fifth edition staging system was significantly related to FFS and OS after allowing for the fourth edition (FFS: P= 0.002; OS: P = 0.005), but the fourth edition was not significantly related to FFS or OS after allowing for the fifth edition (FFS: P = 0.96; OS: P = 0.96). This study confirms the prognostic superiority of the fifth edition UICC staging system over the fourth edition staging system in an Australian NPC population. Copyright (2004) Blackwell Science Pty Ltd

  10. Unions, Vitamins, Exercise: Unionized Graduate Students

    Science.gov (United States)

    Dewberry, David R.

    2005-01-01

    After the turbulent labor history of America in the early to mid twentieth century, there has been a general decline of unions. Nevertheless, many graduate school teaching assistants are unionizing in attempts to gain better pay and benefits and remove themselves from an "Ivory Sweatshop." This article discusses a history of unions…

  11. Solution IMRT static of a radiotherapy treatment of breast cancer with lymphangitis; Solucion IMRT estatica de un tratamiento radioterapico del cancer de mama con linfangitis carcinomatosa cutanea

    Energy Technology Data Exchange (ETDEWEB)

    Puertolas Hernandez, J. R.; Iriondo Igerabide, U.; Urraca de la Serna, J. M.; Lozano Flores, F. J.; Pino Leon, C.; Larretxa Etxarri, R.

    2013-07-01

    In breast cancer, the planning of treatment with IMRT technique mode static MLC has been efficient to get a perfect union of doses in the skin between the lower limit of the supraclavicular fields and the upper limit of the tangential fields. The technique Planning requires the creation of auxiliary volumes that allow you to manage the particularities inherent to the tangential fields of breast. (Author)

  12. Association between NFKB1 −94ins/del ATTG Promoter Polymorphism and Cancer Susceptibility: An Updated Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Xiao Yang

    2014-01-01

    Full Text Available Nuclear factor-κB is associated with the pathogenesis of numerous malignancies, and the functional polymorphism −94ins/del ATTG (rs28362491 in the human NFKB1 gene is associated with cancer risk. Previous studies on the association between the −94ins/del ATTG polymorphism and cancer risk reported conflicting results. To clarify this relationship, we performed a meta-analysis of 21 case-control studies involving 6127 cases and 9238 controls. We used pooled odds ratios (ORs with their 95% confidence intervals (95% CIs to assess the association. We found that the NFKB1 promoter −94ins/del ATTG polymorphism was significantly associated with cancer risk in four genetic models (ins/ins versus del/del, OR = 1.47, 95% CI = 1.11–1.93; dominant model, OR = 1.26, 95% CI = 1.03–1.53; recessive model, OR = 1.26, 95% CI = 1.05–1.51; ins allele versus del allele, OR = 1.19, 95% CI = 1.05–1.35. Stratified analyses revealed a significant association between the polymorphism and ovarian, oral, and prostate cancers. Similar results were determined in an Asian population and not in a Caucasian population. Thus, our results suggested that the polymorphism can contribute to cancer risk. Moreover, the polymorphism can exert race- and cancer-specific effects on cancer risk. Further large-scale and functional studies are necessary to elucidate this possible effect.

  13. Credit Union Headquarters

    Data.gov (United States)

    Department of Homeland Security — The National Credit Union Administration (NCUA) is the independent federal agency that charters and supervises federal credit unions. NCUA, backed of the full faith...

  14. Efecto del procedimiento de soldadura sobre las propiedades de uniones soldadas de aceros microaleados para cañería Welding procedure effect on the properties of microalloyed steel welded joints for metal fabrication

    Directory of Open Access Journals (Sweden)

    Mónica Zalazar

    2009-03-01

    Full Text Available El objetivo del trabajo fue, en esta primera etapa, comparar las propiedades mecánicas y la microestructura del acero HIC, aleado al Nb-Ti-Cu-Ni, resistente a la corrosión, con las del acero normal NOR, microaleado con Nb-V-Ti, ambos caracterizados mediante análisis químico, mediciones de dureza, estudios metalográficos y ensayos de tracción e impacto. Con el fin de establecer la temperatura de precalentamiento óptima se realizaron ensayos de soldabilidad Tekken a distintas temperaturas y de acuerdo con la Norma JIS Z 3158. Luego se llevaron a cabo soldaduras circunferenciales de cañerías fabricadas con ambos aceros diseñándose procedimientos para la utilización, por un lado, de electrodos revestidos (SMAW: shielded metal arc welding, electrodos de distintos proveedores para todas las pasadas y por el otro, la primera pasada usando soldadura automática con alambre macizo bajo CO2 (GMAW: gas metal arc welding y el resto de las mismas con alambre tubular autoprotegido (FCAW-S: flux cored arc welding-selfshielded. Las soldaduras fueron calificadas de acuerdo con el Código API 1104. Los resultados de los análisis metalográficos y los ensayos mecánicos de tracción, dureza e impacto de las juntas soldadas revelaron la influencia de los consumibles de soldadura y del metal base en las propiedades de las uniones. Se observaron diferencias en las propiedades de las uniones soldadas con consumibles de igual especificación y distintos proveedores. De las diferentes combinaciones ensayadas se definieron valores óptimos para la soldadura de estos aceros.The objective of this work was, in this first step, to compare mechanical property and microstructure of the steel HIC, alloyed with Nb-Ti-Cu-Ni, corrosion resistant, to those of a normal steel NOR, microlloyed with Nb-V-Ti, characterized through chemical analysis, hardness measurements, metallographic studies and tensile and Charpy-V properties. The preheating temperature was established

  15. Users and Union Catalogues

    Science.gov (United States)

    Hartley, R. J.; Booth, Helen

    2006-01-01

    Union catalogues have had an important place in libraries for many years. Their use has been little investigated. Recent interest in the relative merits of physical and virtual union catalogues and a recent collaborative project between a physical and several virtual union catalogues in the United Kingdom led to the opportunity to study how users…

  16. Linfadectomy in cancer treatment colon rectum; Linfadectomia en el Tratamiento del Cancer colorrectal

    Energy Technology Data Exchange (ETDEWEB)

    Canesa, C

    2003-01-15

    The purpose of this revision is to describe the anatomical basic aspects and histopatologicos of interest in the lymphatic dissection and to discuss the list of the radical linfadectomy in the treatment of the cancer colon rectum.

  17. EL PARTIDO COMUNISTA DE CHILE Y SUS POLÍTICAS ALIANCISTAS: DEL FRENTE POPULAR A LA UNION NACIONAL ANTIFASCISTA, 1935-1943

    Directory of Open Access Journals (Sweden)

    Hernán Venegas Valdebenito

    2011-05-01

    Full Text Available RESUMEN Desde mediados de la década de 1930 el PCCh definió una alternativa de su propuesta política para alcanzar la revolución en Chile, por etapas y gradualmente. Esta transformación fundamental en el devenir de la organización derivó, en el largo plazo, en un conjunto de fricciones dentro de la izquierda chilena en la década de los treinta. El PCCh desarrolló la convicción de que un cambio social significativo sería el resultado de avances cualitativos en un proceso de modificaciones democráticas implementadas desde la institucionalidad estatal. Con ello, se descartaban como inviables y aventuradas las corrientes de la izquierda chilena que propiciaban el salto inmediato a una revolución socialista. Esto suponía también la relegación de la estrategia militar como vía para la obtención del poder, por lo menos mientras las condiciones de ampliación del juego democrático estuviesen abiertas como posibilidad de ascenso de las masas al poder. Palabras claves: comunismo, coaliciones, Frente Popular, masas. ABSTRACT Since the mid 1930s the Chilean Communist Party defined a policy alternative to its proposal for achieving revolution in Chile, in stages and gradually. This fundamental change in the future of the organization resulted in the long term, in a series of frictions within the Chilean left during that decade. The party developed the belief that significant social change is the result of qualitative progress in a democratic process of changes implemented from state institutions. This meant the dismissel, as unworkable and risky, flows the traditional stance of the Chilean left immediate leap to a socialist revolution. This also meant the relegation of military of strategy as a route to empowerment, at least until the conditions of enlargement of the democratic sistem were mature for the masses rise to power. Keywords: communist, alliance, popular front, masses.

  18. Systematic Review of Brain Metastases in Patients With Non-Small-Cell Lung Cancer in the United States, European Union, and Japan.

    Science.gov (United States)

    Fenske, D Christian; Price, Gregory L; Hess, Lisa M; John, William J; Kim, Edward S

    2017-11-01

    Brain metastases (BRM) occur frequently in non-small-cell lung cancer (NSCLC) and present a substantial unmet medical need. Previous literature on global BRM prevalence, treatment patterns, costs, and outcomes typically has described a subset of these factors. The primary objective of this systematic literature review was to summarize BRM-related epidemiology, treatment patterns, costs, and survival of patients with NSCLC in the United States, European Union, and Japan. The study was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards. Literature searches were conducted in PubMed, Ovid MedLine, and Embase to identify studies published between 2003 and 2014. Peer-reviewed, English language, and human observational studies of patients with NSCLC and BRM were identified. Demographic characteristics, treatment patterns, histology subtype, costs, and survival data were extracted into Microsoft Excel and descriptively analyzed using SAS version 9.2 (SAS Institute, Inc). Of 8257 studies, 243 were eligible. Data from 46,422 patients with NSCLC and 27,907 patients with BRM were summarized. Radiation therapy was used by 70.7% (n = 19,736) of the total BRM population, followed by systemic therapy (8.9%, n = 2497), and surgery (6.1%, n = 1690). Reported median survival was 9.78 months ranging from 2.5 to 38 months. Radiation therapy had the best outcome at 10.0 months with 41.6% (n = 101) of the studies reporting the use of stereotactic radiosurgery. Highly variable median survival and treatment patterns were reported between countries. Costs and histology subtype data were not reported for most countries, highlighting the need for additional research to describe the economic burden of BRM and improve the diagnosis, prognosis, and prescription of effective therapies. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Increased Risk for Other Cancers in Addition to Breast Cancer for CHEK2*1100delC Heterozygotes Estimated From the Copenhagen General Population Study

    DEFF Research Database (Denmark)

    Näslund-Koch, Charlotte; Nordestgaard, Børge G; Bojesen, Stig E

    2016-01-01

    % CI, 1.01 to 1.85) for men (sex difference: P = .63). For CHEK2*1100delC heterozygotes compared with noncarriers, the age- and sex-adjusted hazard ratios were 5.76 (95% CI, 2.12 to 15.6) for stomach cancer, 3.61 (95% CI, 1.33 to 9.79) for kidney cancer, 3.45 (95% CI, 1.09 to 10.9) for sarcoma, and 1...

  20. Influencia del medio aromático en la transferencia del protón y determinación de los mínimos de potencial de algunas uniones 0-H ...N

    Directory of Open Access Journals (Sweden)

    Oscar Osorno R.

    2009-07-01

    Full Text Available Los complejos formados por unión hidrógeno en los sistemas 2,4,6 -Triclorofenol-Trietilamina y Pentaclorofenol-Trietilamina forma pares iónicos cuando se encuentran en un medio aromático y complejos normales cuando se encuentran en un medio no aromático como el ciciohexano y el tetracloroetileno. El estudio dieléctrico y de espectroscopia U.V. han permitido obtener los momentos dipolares de las formas tautoméricas en equilibrio y sus fracciones molares, tanto en los solventes puros como en mezclas benceno-ciclohexano. Por medio de las medidas calorimétricas efectuadas, se obtienen las entalpias de complejación para los sistemas en benceno y tetracloroetileno y a partir de éstas, es posible determinar los calores de formación del complejo normal y del par iónico. Utilizando una función potencial adecuada para la unión 0-H N, se deduce la distancia O N y la posición de equilibrio del protón en la unión, las cuales reproducen las entalpias de formación halladas experimentalmente.

  1. Frequency of the CHEK2 1100delC mutation among women with breast cancer: an international study.

    Science.gov (United States)

    Zhang, Shiyu; Phelan, Catherine M; Zhang, Phil; Rousseau, Francois; Ghadirian, Parviz; Robidoux, Andre; Foulkes, William; Hamel, Nancy; McCready, David; Trudeau, Maureen; Lynch, Henry; Horsman, Douglas; De Matsuda, Maria Lourdes Leon; Aziz, Zeba; Gomes, Magda; Costa, Mauricio Magalhaes; Liede, Alexander; Poll, Aletta; Sun, Ping; Narod, Steven A

    2008-04-01

    A founder allele in the CHEK2 gene (1100delC) has been associated with an elevated risk of breast cancer. This allele is responsible for the majority of CHEK2-associated breast cancers in women from northern European countries; however, within Europe, it seems to be rare in countries that are close to the Mediterranean. The frequency of the 1100delC allele has not been measured in non-White populations. We measured the frequency of the CHEK2 founder allele in 3,882 breast cancer patients and 8,609 controls from various countries. The allele was not seen among Asian patients (from Pakistan or the Philippines) and was present in 1 of 155 cases from Brazil. Among White women, the allele was present in 1.5% of 825 familial cases of breast cancer and in 0.7% of 1,106 patients with nonfamilial breast cancer. The allele was equally frequent in Jewish and non-Jewish patients. We estimate that the CHEK2 1100delC allele is associated with an odds ratio of 2.6 for breast cancer, which corresponds to a lifetime risk of approximately 24% in Ontario.

  2. Estudio del daño por hidrógeno en uniones soldadas de un acero API 5L X52

    Directory of Open Access Journals (Sweden)

    Réquiz, R.

    2008-04-01

    Full Text Available The main objective of the present investigation was to study the susceptibility to hydrogen damage on a type API 5L X52 steel welded by electrical resistance. Several techniques, such as hydrogen permeation and cathodic charging were used. The metallic material was characterized using SEM and TEM. The base metal microstructure was very similar to that one corresponding to the welded area. This microstructure was mainly comprised by ferrite and perlite, differing only in the grain size. Therefore, the susceptibility to hydrogen damage was similar in both cases. It is worth mentioning that the welded area has very small dimensions. Indeed, the fusion zone is only 5 mm wide while the heat affected zone is 1 mm wide. The hydrogen damage observed was mainly in the form of blisters, which were associated to the presence of aluminum rich inclusions. Also, it was noticed partial inclusion dissolution and some matrix attack adjacent to the inclusions.

    En la presente investigación se estudió la susceptibilidad al daño por hidrógeno en un acero API 5L X52 soldado por resistencia eléctrica. Para ello, se emplearon técnicas de permeación y de carga catódica de hidrógeno. El material fue caracterizado mediante microscopía electrónica de barrido y de transmisión. La susceptibilidad al daño por hidrógeno fue similar tanto en el metal base como en el cordón de soldadura. Este comportamiento se vincula a la microestructura homogénea constituida por perlita y ferrita, que presentan ambos, aun cuando existen diferencias en el tamaño de grano. El cordón de soldadura tenía dimensiones muy pequeñas, donde la zona de fusión y la afectada por el calor poseen espesores de 5 mm y 1 mm, respectivamente. El daño inducido por hidrógeno se presentó en forma de ampollas en la superficie del material, asociado, principalmente, a la presencia de inclusiones globulares y semiglobulares ricas en aluminio. Además, se manifestó una disoluci

  3. Trade union revitalisation

    DEFF Research Database (Denmark)

    Ibsen, Christian Lyhne; Tapia, Maite

    2017-01-01

    In this article, we review and assess research on the role of trade unions in labour markets and society, the current decline of unions and union revitalisation. The review shows three main trends. First, trade unions are converging into similar strategies of revitalisation. The ‘organising model...... their traditional strongholds of collective bargaining and corporatist policy-making. Second, research has shown that used strategies are not a panacea for success for unions in countries that pearheaded revitalisation. This finding points to the importance of supportive institutional frameworks if unions...... in adverse institutional contexts, can be effective when they reinvent their repertoires of contention, through political action or campaigning along global value chains....

  4. FACTORES PRONOSTICOS DEL CANCER DE MAMA Y ONCOGEN HER2/NEU

    Directory of Open Access Journals (Sweden)

    F.J. Martín Gil

    2006-08-01

    Full Text Available ABSTRACT: PRONOSTIC FACTORS OF BREAST CANCER AND HER2/NEUThe breast cancer constitutes the main cause of death by cancer in women of our country. In spite of the efforts directed in campaigns of precocious detection, the incidence continues increasing in a 1% approximately per year and the rate of mortality stay constant. Therefore it is of great importance to consolidate efforts directed towards the development and use of therapeutic and diagnostic methods. The development of neoplasia is directly related to successive genetic mutations in which cellular oncogenes are involved.It is known that in case of breast cancer the Her2/neu oncogene (Human epidermal growth receptor-2 factor is amplified and/or overexpressed in approximately a 30% of the cases. The knowledge of a positive result for Her2/neu overexpression has an important value in prognosis as it is associated to a greater aggressiveness of the disease. Also, this gene can be an answer marker to certain treatments like trastuzumab. RESUMEN:El cáncer de mama (CM constituye la principal causa de muerte por cáncer en mujeres de nuestro país. A pesar de los esfuerzos dirigidos hacia las campañas de detección precoz, la incidencia sigue aumentando aproximadamente en un 1% por año y la tasa de mortalidad sigue manteniéndose constante.Es por ello de gran importancia aunar esfuerzos dirigidos al desarrollo y utilización de métodos diagnósticos y terapéuticos. El desarrollo de una neoplasia está directamente relacionado con mutaciones genéticas sucesivas en las que están involucrados oncogenes celulares.En el caso del cáncer de mama se sabe que el encogen Her2/neu (Human epidermal growth factor receptor-2 está amplificado y/o sobreexpresado en aproximadamente un 30% de los casos. El conocimiento de la positividad del mismo tiene un importante valor pronóstico asociándose a una mayor agresividad de la enfermedad. Así mismo dicho gen puede ser un marcador predictivo de respuesta

  5. BANKING UNION - ROMANIAN PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Coroiu Sorina Ioana

    2015-07-01

    Full Text Available The financial crisis showed that banks were not able to face the loss, because there is no framework for a resolution, so that it intervened with money from taxpayers. So, it has been highlighted the need to update the regulations applicable to the banking sector. Creating a single supervisory mechanism in the fall of 2014 was a time reference point to achieve a banking union in Europe. Banking Union is one of the four foundations for a genuine Economic and Monetary Union. The paper’s purpose is to analyze the Banking Union structure, based on three pillars: (i The Single Supervisory Mechanism - the transfer of the main responsibility regarding banking supervision from national to European level, (ii The Single Resolution Mechanism - introduction of common provisions to ensure legal support required to manage bank failures problem, (iii The Deposit Guarantee Schemes - harmonization of deposit guarantee rules. These measures were adopted at European Union level to ensure the stability of the European banking system and to prevent future crises. Because countries that are not part of the euro area are not required to join the Banking Union, the dilemma of these countries lies in the decision to join the Banking Union quickly or to wait. It is the case of Romania, also, so, this paper analyze the opportunity of Romania's accession to the Banking Union before adopting the euro. There are analyzed the advantages and disadvantages of Romania's participation in the Banking Union, showing that, in the context of single currency introduction, Romania's participation is required. So far, there are reduced debates regarding the need, advantages and disadvantages of Romania's participation in the European Banking Union, the top representatives of the National Bank of Romania being among the few who expressed their views in public and published papers on the subject.

  6. Evaluación del programa de detección precoz de cáncer cervicouterino en Consolación del Sur Assessment of Cervical Cancer Early Detection Program in Consolacion del Sur municipality

    Directory of Open Access Journals (Sweden)

    Maricel Ramírez Valle

    2013-02-01

    Full Text Available Introducción: la evaluación del Programa de Detección Precoz de Cáncer Cervicouterino debe realizarse con frecuencia para ir resolviendo las dificultades presentes. Objetivo: evaluar el desarrollo y la calidad del Programa de Detección Precoz de Cáncer Cervicouterino en Consolación del Sur en el período 2005-2007. Material y método: se realizó un estudio observacional, retrospectivo y transversal con componentes analíticos. Universo (N =34570 mujeres de =15 años. Marco muestral 22233 mujeres comprendidas entre 25-59 años (las contempladas en el Programa de Detección Precoz de Cáncer Cervicouterino. Se calculó la incidencia anual de lesiones, la edad de presentación de las mismas. Se evaluó la calidad del diagnóstico citológico mediante las pruebas de rendimiento. Se utilizaron los estadígrafos X², concordancia Kappa de Cohen, y coeficiente de correlación de Pearson. Resultados: la cobertura continúa baja, con variaciones en las diferentes áreas de salud del municipio. Sin embargo, el diagnóstico citológico está dentro de rangos internacionales con una sensibilidad de más del 60 % y una eficacia global de más del 70 %. La incidencia anual de lesiones de bajo grado se duplica al final del período, pero las de alto grado se mantienen estables. Los carcinomas invasores aunque escasos continúan presentándose. Conclusiones: el Programa de Detección Precoz de Cáncer Cervicouterino en Consolación del Sur muestra logros, pero aún hay deficiencias tanto en la atención primaria de salud, como en la secundaria.Introduction: the assessment of Cervical Cancer Early Detection Program should be carried out frequently to solve current difficulties. Objective: to assess the development and quality of Cervical Cancer Early Detection Program in Consolacion del Sur during 2005-2007. Material and Method: an observational, retrospective and cross-sectional study with analytical components was conducted. The target group involved

  7. Involvement of Union Fenosa skills in the thermohydraulic area of the Jose Cabrera NPP PSA. Applications of the RELAPS5/MOD2 Code; Implicacion de las capacidades de union fenosa dentro del area de termohidraulica en el APS de la C.N. Jose Cabrera. Aplicaciones del codigo RELAP5/MOD2

    Energy Technology Data Exchange (ETDEWEB)

    Martin, L; Saenz Tejada, P [Empresarios Agrupados, A.I.E., Madrid (Spain)

    1993-12-15

    When performing a level 1 Probabilistic Safety Analysis (PSA) on a standard power plant, in order to model plant response to the potential occurrence of the various initiating events postulated in a PSA, reference documentation applicable to the type of plant in question is frequently consulted. Because of the specific design characteristics of the Jose Cabrera NPP, most of the reference documentation for the W-PWR-type power plants is not applicable to this plant. To fill in these gaps in the documentation and to construct the most realistic model of plant behaviour possible, assistance was sought from Union Fenosa by way of infrastructure, capabilities and thermohydraulic experience of the Nuclear Engineering and Fuel Group, and especially the use of calculations performed with the RELAP5/ MOD2 code. This paper will provide an overview of the general assistance rendered to the PSA by the technical experts in thermohydraulics, the calculations performed with RELAP5/MOD2 and the influence all of this has had on the development, quality and results of the Jose Cabrera NPP level 1 PSA Project. (author)

  8. Uniones de nitruro de silicio Superaleaciones

    OpenAIRE

    Barea, R.; Miranzo López, Pilar; Osendi, María Isabel

    2000-01-01

    [ES] El posible uso del nitruro de silicio en el ámbito industrial se ve limitado por la dificultad y el coste que supone mecanizar geometrías complicadas. En el presente trabajo se estudia la posibilidad del uso de superaleaciones como interlámina de unión entre piezas de este material. Se han seleccionado tres superaleaciones con base niquel-cromo debido a su interés tecnológico. Las uniones se han llevado a cabo por termocompresión en vacío, utilizando varias presiones y temperatu...

  9. Bases moleculares del cáncer colorrectal = Molecular bases of colorectal cancer

    Directory of Open Access Journals (Sweden)

    Muñetón Peña, Carlos Mario

    2012-04-01

    Full Text Available Se considera que el cáncer colorrectal (CCR es un problema mundial de salud pública; es el tercer cáncer más común en hombres y el segundo en mujeres. Su distribución geográfica es variable: las tasas de incidencia son altas en países desarrollados de Europa, Norteamérica y Oceanía y bajas en países de regiones subdesarrolladas como África y Suramérica. Sin embargo, los datos de estudios recientes publicados por la Agencia Internacional de Investigaciones en Cáncer (IARC, International Agency for Research on Cancer muestran un aumento rápido en la incidencia de CCR en los períodos 1983-1987 y 1998-2002 en países en vías de desarrollo (1, mientras que en países desarrollados la incidencia se ha estabilizado y en muchos casos ha disminuido (2. La carcinogénesis del CCR es un proceso de múltiples etapas, caracterizado por una gran inestabilidad genómica que permite la acumulación de mutaciones en protoncogenes y genes supresores de tumores, alteración en la expresión de genes y producción de proteínas no funcionales, que les confieren a las células ventajas de proliferación y aumento de la supervivencia. La inestabilidad genómica del CCR se produce por diferentes vías; entre las más importantes se encuentran: la de inestabilidad cromosómica (CIN, la de inestabilidad microsatelital (MSI y la de metilación.

  10. Trade Union Organisers in Trade Union Organising Strategies: building workplace unionism or reinforcing bureaucracy

    OpenAIRE

    Looker, Gerard

    2015-01-01

    This thesis considers the role of union full time officers in union organising strategies. Two decades of promoting union organising influenced by models developed by the AFL-CIO, has failed to arrest the decline of UK trade unions let alone produce evidence of renewal. Focusing mainly on one region in the UKs largest public sector trade union, Unison, the research provides for a detailed account of how organising strategies affect union work, presenting thick and deep data from full time off...

  11. Molecular genetics of colorectal cancer Genética molecular del cáncer colorrectal

    Directory of Open Access Journals (Sweden)

    D. Cruz-Bustillo Clarens

    2004-01-01

    Full Text Available Colorectal tumours constitute an excellent system to study carcinogenesis and the molecular events implicated in the development of cancer. Attending to the way it is transmitted, colorectal cancer may appear in one of three forms: sporadic, familial, and hereditary. The sporadic form is most common and has no familial or hereditary associated factor thus far, while familial and hereditary forms show the same inheritance pattern. Hereditary colorectal cancers develop by means of defined stages that go from lesions in the crypt of the colon through adenomas to manifest cancer. They are characterised by the accumulation of multiple mutations in tumour suppressor genes and oncogenes that affect the balance between cell proliferation and apoptosis. The colorectal carcinogenesis pathway is not unique and there are probably several ways for the initiation, development and progression of colorectal tumours.Los tumores colorrectales constituyen un excelente sistema para estudiar la carcinogénesis y los eventos moleculares involucrados en el desarrollo de un tumor. El cáncer colorrectal puede presentarse en tres formas, según su forma de transmisión: esporádico, familiar y hereditario. La forma esporádica que es la mayoritaria, no tiene hasta el momento ningún factor familiar o hereditario asociado, mientras que las formas familiares y hereditarias siguen un patrón de herencia en la propensión familiar a padecerlo. Los cánceres colorrectales hereditarios se desarrollan mediante etapas definidas que van desde lesiones en la cripta del colon a través de adenomas hasta manifestar el cáncer y se caracterizan por la acumulación de múltiples mutaciones en genes supresores de tumor y oncogenes que afectan el balance entre la proliferación celular y la apoptosis. La vía de carcinogénesis colorrectal no es una sola y probablemente existan varios caminos para el inicio, desarrollo y progresión de un tumor colorrectal.

  12. Uso potencial de componentes del veneno de serpiente en el tratamiento del cáncer Potential use of snake venom components in cancer treatment

    Directory of Open Access Journals (Sweden)

    Dan Vivas

    2012-09-01

    Full Text Available El desarrollo del cáncer es posible en la medida que las células tumorales proliferen, se dispersen e invadan otros tejidos del cuerpo. Las integrinas son una familia de receptores heterodiméricos de superficie celular que cumplen un papel crucial en el desarrollo de la angiogénesis, crecimiento y metástasis de un tumor señalándolas como un atractivo blanco terapéutico. Los venenos de serpientes contienen péptidos de bajo peso molecular conocidos como desintegrinas, las que se unen con una alta afinidad a las integrinas e inhiben su accionar en un proceso cancerígeno. En el siguiente articulo revisamos los resultados de investigaciones, tanto in vitro como in vivo, que han mostrado resultados promisorios, por lo cual el uso de las desintegrinas podrían constituir una alternativa promisoria para el tratamiento de diversas neoplasiasCancer can develop to the extent tumor cells grow, divide and grow into other body tissues. Integrins are a family of cell-surface heterodimeric receptors that play an important role in the development of tumor angiogenesis, growth and metastasis, thus being recognized as an attractive therapeutic target. Snake venom contains low-molecular weight peptides known as “disintegrins” that bind to integrins with high affinity, and prevent their action in cancer. In the next article, we go over the results of investigations, both in vitro and in vivo, which have shown promising results, thus revealing that the use of disintegrins could be a promising alternative for the treatment of different neoplasias

  13. Union banking a step towards achieving fiscal Union in the European Union

    Directory of Open Access Journals (Sweden)

    Ionuţ Marius Croitoru

    2015-05-01

    Full Text Available Introduction: Union policy needs in addition to the official language of four major components: a monetary union, a fiscal union, a union diplomatic and military union A stage in the Union is the Union banking tax. Materials and Methods: Union Bank has three pillars: a single banking supervisor (single supervisory mechanism, the only mechanism of bank resolution and a single scheme of bank guarantees. Results and conclusions: Union Bank, strengthen supervision is an inevitable process, and Romania will have to enroll in it. Option Romania is to be part of Romania deaorece bank Union can not remain outside the structures of decision as long as banks operating in Romania are predominantly Eurozone.

  14. Caracterización estadística del cáncer de mama en la provincia de Pinar del Río Statistical characterization of breast cancer in Pinar del Rio province

    Directory of Open Access Journals (Sweden)

    Pablo González Ruiz

    2010-12-01

    Full Text Available Dentro de las enfermedades no transmisibles que causan cada año una alta mortalidad en la provincia de Pinar del Río, están las provocadas por el cáncer de mama. Esto genera años de vida perdidos por la mortalidad, de ahí que el objetivo sea: reflejar esta situación por municipios entre los años de 2003 al 2009, con el interés de brindar una información adicional y complementaria al Departamento Provincial de Estadística de Salud Pública. Los indicadores promedio de años de vida perdidos y promedio de años de vida vividos reflejan con más claridad esta situación. Los primeros se calcularon a partir de los estimados de esperanza de vida y los segundos, a partir de la suma de las edades de todas las fallecidas en los 7 años entre el total de estas. El cálculo se realizó sobre la base de tablas estadísticas aportadas por el Departamento de Provincial Estadística de Salud Pública, empleando para esto el sistema Microsoft Excel. Se utilizó un estudio longitudinal retrospectivo y descriptivo en los 14 municipios de la provincia. La novedad del estudio amen de lo antes mencionado está en que contempla por cada municipio como se comporta esta situación, sensibilizando al personal de la atención primaria de salud en la detección temprana del cáncer de mama. El cáncer de mama en el período que se analiza tuvo una evolución desfavorable en lo que se refiere a los años de vida saludables perdidos, destacándose el municipio de Pinar del Río.Among non-contagious diseases provoking an annual high mortality rate in Pinar del Rio province are those provoke by breast cancer. The objective of this study was to quantify, for first time- where it had been possible to investigate- the burden associated with breast cancer in Pinar del Rio province, aimed at offering and additional and complementary information to the Provincial Department of Statistics in Public Health. The average years of potential life lost and quality

  15. Are unions an anachronism?

    Science.gov (United States)

    Schrank, R

    1979-01-01

    The labor movement in the United States has its roots deep in the soil of worker discontent over grueling working conditions, low pay, and indifference of bosses, who profited from others' sweaty labor. As more and more grubby jobs are replaced by technological innovations, as work becomes more abstract and everyone wears a white shirt, and as managers schooled in motivation theory and humane ideals of participation replace the owner-bosses of yesterday, what role will the unions have left to play? The author of this article, who has been in both the labor force and management, explores what the changes in the labor market will be in the future and what these changes will mean for labor-management relations. He does not conclude that there is no role for unions-only that it will be very different and that to survive unions will have to tackle new issues in the workplace. That adaptation will affect management's stance as well.

  16. Analysis of 6174delT Mutation in BRCA2 Gene by Mutagenically Separated PCR Among Libyan Patients with Breast Cancer

    Directory of Open Access Journals (Sweden)

    Lamia Elfandi

    2016-03-01

    Full Text Available Background: Breast cancer is the most common malignancy among women. It is estimated that 1 in 10 women worldwide is affected by breast cancer during their lifetime. In 5 to 10% of breast cancer patients, the disease results from a hereditary predisposition, which can be attributable to mutations in either of two tumor suppressor genes, BRCA1 and BRCA2 to a large extent. BRCA2 6174delT mutation constitutes the common mutant alleles which predispose to hereditary breast cancer in the Ashkenazi population with a reported carrier frequency of 1.52%. In this study, we investigated the presence of the 6174delT mutation of the BRCA2 gene in Libyan woman affected with breast cancer and compared the results with those of other population groups.Methods: Eighty- five Libyan women with breast cancer in additions to 5 relatives of the patients (healthy individuals were recruited to this study. We obtained clinical information, family history, and peripheral blood for DNA extraction and analyzed the data using multiplex mutagenic polymerase chain reaction (MS-PCR for detection of 6174delT mutation in the BRCA2 gene. Results: The 6174delT of the BRCA2 gene was not detected either in the 85 patients with breast cancer (18 with familial breast cancer and 67 with sporadic breast cancer nor in the 5 healthy individuals. Conclusions: The present study showed that the 6174delT of the BRCA2 gene was not detectable using mutagenic PCR in the Libyan patients with breast cancer and can be considered to be exceedingly rare

  17. European [Security] Union

    DEFF Research Database (Denmark)

    Manners, Ian James

    2013-01-01

    The past 20 years, since the 1992 Treaty on European Union, have seen the gradual creation of both an “Area of Freedom, Security and Justice” and a “Common Foreign and Security Policy”. More recent is the development of a “European Neighbourhood Policy” over the past 10 years. All three...... of these policies involved the navigation and negotiation of security, borders and governance in and by the European Union (EU). This article analyses these practices of bordering and governance through a five-fold security framework. The article argues that a richer understanding of EU security discourses can...

  18. Trade Union Channels for Influencing European Union Policies

    Directory of Open Access Journals (Sweden)

    Bengt Larsson

    2015-10-01

    Full Text Available This paper analyzes what channels trade unions in Europe use when trying to influence European Union (EU policies. It compares and contrasts trade unions in different industrial relations regimes with regard to the degree to which they cooperate with different actors to influence EU policies, while also touching on the importance of sector differences and organizational resources. The study is based on survey data collected in 2010–2011 from unions affiliated with the European Trade Union Confederation and from below peak unions in 14 European countries. Results of the survey show that the ‘national route’ is generally the most important for trade unions in influencing EU policies in the sense that this channel is, on average, used to the highest degree. In addition, the survey delineates some important differences between trade unions in different industrial relations regimes with regard to the balance between the national route and different access points in the ‘Brussels route’.

  19. Teaming Up with Unions.

    Science.gov (United States)

    Geber, Beverly

    1987-01-01

    The author discusses the concept, first encouraged by Irving Bluestone of the United Auto Workers, that union and management personnel should work together to achieve company goals. The history of this cooperative effort movement within the United Auto Workers is described. (CH)

  20. Perspectives and expectations of union member and non- union member teachers on teacher unions

    Directory of Open Access Journals (Sweden)

    Tuncer FİDAN

    2015-12-01

    Full Text Available Unions, which can be regarded as one of the constitutive elements of democracy, are the pressure groups in political and social fields. Unions were born out of industrial confrontations and expanded into the field of public services over time, and thus teachers – who are also public employees-, also obtained the right to establish and affiliate to unions. In this research the views of union member and non-union member teachers on the most important functions and operational effectiveness of unions, teachers’ expectations from unions and teachers’ evaluation of the solidarity, competition and cooperation between unions were determined and the perspectives of teachers on unionization were revealed. qualitative research design was used. The data needed were collected through semi-structured interviews from volunteering union member and non-union member teachers who were working in the primary and secondary schools in Ankara province and who were selected through “maximum variation sampling approach”. The data were then analyzed by using the content analysis technique. In conclusion, it was found that political ideology was the most important reason for membership of teachers’ unions. Protection and development of personal rights was found to be the most important function of teacher unions and unions were thought to be insufficient in performing those functions.

  1. The Development of Trade Unionism.

    Science.gov (United States)

    Parker, Ronald W.

    1979-01-01

    Traces the growth and evolution of the British labor union movement, troubles between the national officials and the local shop stewards, class differences and conflict between the artisans and laborers, violence between unions, and eventual transition to peaceful constitutionalism. (MF)

  2. Union Directions - Army Response.

    Science.gov (United States)

    1985-12-06

    reflects the long-held belief in the Army that employee participation in decisions that affect their worklife is healthy and desirable. Although some...pluralistic society, checks and balances are as important for the economy as for the government. Business executives who salivate at the thought of vanishing...Unions. Reading, MA: Addison-Wesley, 1976. 37. National Federation of Federal Employees. NFFE’s Guide to Quality of Worklife Programs. No. G-21

  3. European Union Budget Politics

    DEFF Research Database (Denmark)

    Citi, Manuele

    2015-01-01

    The marginal involvement of the European Union (EU) in redistributive policies and its limited fiscal resources have led to a notable lack of attention by EU scholars towards the EU budget and its dynamics. Yet the nature of the budgetary data and their high usability for statistical analysis make...... to form winning coalitions in the Council, the ideological positioning of the co-legislators and the inclusion of the cohesion countries have played a significant role in driving budget change....

  4. TRATAMIENTO QUIRÚRGICO DEL CANCER GÁSTRICO: UNA VISIÓN ACTUALIZADA

    Directory of Open Access Journals (Sweden)

    José Felix Patiño Restrepo

    1984-09-01

    Full Text Available

    La conducta adoptada en el Hospital de La Samaritana coincide con algunos preceptos actualmente preconizados por la Clínica Lahey (54, uno de los centros que en una época promulgaron la extirpación radical y que mayor influencia produjeron en muchos países del mundo, así como con los preconizados por la Clínica Cleveland (55, institución que ha modificado muchos de los tradicionales principios de radicalidad en la cirugía del cáncer:

    1. Todo paciente con cáncer gástrico es sometido a exploración quirúrgica;
    2. Si la lesión es resecable, se emprende una operación "curativa", la cual comprende la
    resección del tumor con márgenes suficientes, pero no excesivos, de tejido normal, tratando siempre de conservar un segmento de estómago proximal, y evitando la resección profiláctica del bazo, epiplones y órganos vecinos;
    3. No se realiza la gastrectomía total sino en situaciones en las cuales ésta es la única forma de lograr la extirpación total del tumor, y nunca como terapia paliativa;
    4. Se realizan grandes resecciones sólo para grandes cánceres, y se realizan pequeñas resecciones para tumores pequeños;
    5. Cuando no es posible realizar una resección curativa, se procede con una resección paliativa si ésta es fácilmente realizable y no significa una resección heroica o masiva; específicamente se realizan resecciones paliativas para controlar hemorragia, obstrucción y dolor; nunca debe hacerse una gastrectomía total como procedimiento paliativo, y la gastroenterostomía, la gastrostomía o la yeyunostomía tienen muy escasa indicación en la paliación del cáncer gástrico.
    6. Creemos que en última instancia el pronóstico del paciente depende del tipo y estado del tumor, de su rata de crecimiento y caracteristicas biológicas y de otros factores de la relación tumor/paciente, más que del tipo y la radicalidad del tratamiento quirúrgico empleado.

  5. Impact of the PET/CT in the marshalling of the lung cancer; Impacto del PET/CT en el manejo del cancer de pulmon

    Energy Technology Data Exchange (ETDEWEB)

    Izquierdo F, M C [Hospital Angeles del las Lomas, Huixquilucan, Estado de Mexico (Mexico); Serna M, J A; Quiroz C, O; Luviano V, C; Alcala G, B [Hospital Angeles del Pedregal, Mexico DF. (Mexico)

    2005-07-01

    The lung cancer constitutes one of the main morbimortality causes in our environment, being indispensable to carry out a clinical staging with bigger accuracy that allows to define it extension with two objectives: 1. The surgery determination. 2. To predict the prognosis. At the present time it has been possible to combine the metabolic-functional image with the anatomical image creating the PET/CT modality (Positron Emission Tomography/ Computerized Tomography) with that which has improved substantially the accuracy and localization of the lesions with sensitivity of 81%, specificity of 94% and an accuracy diagnoses of 90%. In conclusion the PET/CT image technique has been indispensable in the oncological patient's handling especially in the patient with lung cancer changing the perspective diagnoses as well as the treatment avoiding invasive methods like the mediastinoscopy until the realization of extensive surgeries. The metabolic with the anatomical image fusion it has been able to locate with more accuracy the lesions to distance especially in mediastinum, as well as staging has been achieved accurately in a single exploration to the patient with lung cancer overcoming the rest of the non invasive diagnostic tests especially in the valuation of the metastatic at distance illness, transforming it into an exploration technique with a high effectiveness at an appropriate cost benefit. (Author)

  6. Impact of the PET/CT in the marshalling of the lung cancer; Impacto del PET/CT en el manejo del cancer de pulmon

    Energy Technology Data Exchange (ETDEWEB)

    Izquierdo F, M.C. [Hospital Angeles del las Lomas, Huixquilucan, Estado de Mexico (Mexico); Serna M, J.A.; Quiroz C, O.; Luviano V, C.; Alcala G, B. [Hospital Angeles del Pedregal, Mexico DF. (Mexico)

    2005-07-01

    The lung cancer constitutes one of the main morbimortality causes in our environment, being indispensable to carry out a clinical staging with bigger accuracy that allows to define it extension with two objectives: 1. The surgery determination. 2. To predict the prognosis. At the present time it has been possible to combine the metabolic-functional image with the anatomical image creating the PET/CT modality (Positron Emission Tomography/ Computerized Tomography) with that which has improved substantially the accuracy and localization of the lesions with sensitivity of 81%, specificity of 94% and an accuracy diagnoses of 90%. In conclusion the PET/CT image technique has been indispensable in the oncological patient's handling especially in the patient with lung cancer changing the perspective diagnoses as well as the treatment avoiding invasive methods like the mediastinoscopy until the realization of extensive surgeries. The metabolic with the anatomical image fusion it has been able to locate with more accuracy the lesions to distance especially in mediastinum, as well as staging has been achieved accurately in a single exploration to the patient with lung cancer overcoming the rest of the non invasive diagnostic tests especially in the valuation of the metastatic at distance illness, transforming it into an exploration technique with a high effectiveness at an appropriate cost benefit. (Author)

  7. Is there a place for assisting therapy in colon rectum carcinoma?; Hay un lugar para la terapia adyuvante en la cirugia del cancer colorerctal?

    Energy Technology Data Exchange (ETDEWEB)

    Veirano Rodriguez, G

    1993-12-01

    Reviving the experience of the past 40 years in the treatment of the cancer color rectal is evident that a remarkable improvement has not existed in the operative mortality and in the percentage of recovery.This panorama is analyzed from the surgeon's optics the different possibilities and radiotherapy,q chemotherapy modalities and of immunotherapy in the assisting of the cancer color rectal as well as its results in centers specialized.Their options and its sequence discuss as well as its association. It concludes that after the stadification pre operation of the cancer color rectal it should be valued together with the specialist oncologist the possibility to carry out the assisting and of persisting in alert attitude before the scientific advances very documented in this aspect of the treatment (Au) [Spanish] Reviviendo la experiencia de los pasados 40 anos en el tratamiento del cancer colorrectal resulta evidente que no ha existido una notable mejoria en la mortalidad operatoria y en el porcentaje de curacion.Ante este panorama se analiza desde la optica del cirujano las distintas posibilidades y modalidades de radioterapia,quimioterapia y de inmunoterapia en la adyuvancia del cancer colorrectal asi como sus resultados en centros especializados.Se discuten sus opciones y su secuencia asi como su asociacion.Se concluye que luego de la estadificacion preoperatoria del cancer colorrectal se deberia valorar en conjunto con los especialistas oncologos la posibilidad de realizar la adyuvancia y de persistir en actitud alerta y espectante ante los avances cientificos bien documentados en este aspecto del tratamiento (AU)

  8. Vascular endothelial growth factor gene polymorphisms in patients with colorectal cancer Polimorfismos del gen del factor de crecimiento vascular endotelial en pacientes con cáncer colorrectal

    Directory of Open Access Journals (Sweden)

    M. Vidaurreta

    2010-01-01

    Full Text Available Background: angiogenesis plays an important role in tumor progression. The vascular endothelial growth factor (VEGF is an important regulator of angiogenesis. In the present study we evaluated single nucleotide polymorphisms (SNPs -2578C > A, -1154G > A, and +936C > T in the VEGF gene, and their prognostic value for patients operated on for colorectal cancer (CRC. Patients and method: VEGF polymorphisms have been analyzed in 177 patients who had undergone surgical resection at Hospital Clínico San Carlos. The analysis of these polymorphisms was performed with specific probes for each nucleotide in a multiplex reaction using real-time PCR. Results: we only found a statistically significant relationship for one of these three polymorphisms, +936C > T, with gender and tumor location; 10.7% of patients heterozygotes for this SNP had tumors located in proximal colon, 35.2% in distal segment and 54.1% in rectum (p = 0.03. Patients with the +936T/T genotype had 100% overall survival (OS. Conclusion: patients with a +936T/T genotype showed increased survival, therefore the +936C > T SNP could be a useful marker in the follow-up and clinical management of patients with colorectal cancer.Introducción: la angiogénesis juega un papel importante en la progresión de los tumores. El factor de crecimiento endotelial vascular (VEGF es un importante regulador de la angiogénesis. En este trabajo se han analizado los polimorfismos de único nucleó-tido (SNP -2578C > A, -1154G > A y +936C > T del gen VEGF en pacientes intervenidos de carcinoma colorrectal, así como su posible implicación pronóstica. Pacientes y método: el estudio de estos SNP se ha realizado en 177 pacientes intervenidos quirúrgicamente de carcinoma colorrectal (CCR en el Hospital Clínico San Carlos. El análisis de los polimorfismos se realizó con sondas específicas para cada nucleótido y se determinó mediante una reacción multiplex mediante real time PCR. Resultados: de los 3

  9. European Union, 2017

    OpenAIRE

    Malone Margaret Mary

    2018-01-01

    The year 2017 was eventful for the EU and its member states. Given the widespread Euroscepticism and populism which appeared to be on the rise last year, election results in the Netherlands, France and Germany were greeted with relief and hope for the future. The EU was in an optimistic mood. European Commission President Jean- Claude Juncker used his State of the European Union speech in September to note that the EU had the ‘wind in its sails’ (Juncker, 2017). At the same time, he cautioned...

  10. Análisis costo beneficio del Programa de Detección Oportuna del Cáncer Cervicouterino Cost benefit analysis of the Cervical Cancer Screening Program

    Directory of Open Access Journals (Sweden)

    PATRICIA HERNÁNDEZ-PEÑA

    1997-07-01

    Full Text Available Objetivo. Determinar el costo beneficio de la reorganización del Programa de Detección Oportuna del Cáncer Cervicouterino (PDOC mediante intervenciones de garantía de calidad. Material y métodos. Se siguieron tres etapas: a identificación y cuantificación de costos; b identificación y cuantificación de beneficios, y c evaluación económica del costo beneficio. Resultados. El costo unitario de operación por citología -obtención, fijación, el traslado al centro de lectura, su tinción e interpretación y la notificación de resultados- se estimó en USD$ 11.6. En conjunto, las intervenciones en calidad al PDOC elevarían el costo de cada citología en 32.7%. Sin embargo, la nueva organización generaría una razón beneficio/costo de 2 y un beneficio neto de 88 millones de dólares para los próximos cinco años. Conclusiones. La operación del programa propuesto resulta socialmente deseable, siempre y cuando las modificaciones se lleven a cabo, particularmente la capacitación, la notificación personalizada de los casos positivos, el incremento de cobertura, la introducción de mecanismos de control de calidad, el monitoreo contínuo y el tratamiento en mujeres con anormalidades detectadas.Objective. Previous researches pointed out the critical changes needed to increase the efficiency of the National Screening Programme of Cervical Cancer in Mexico. These changes were assessed through a cost-benefit analysis. This paper presents the results of that appraisal. Figures are presented as USDollars of 1996 valued as 7.5 pesos for each dollar. Results. The operational unitary cost of the integral process of the cytology –the obtention of the Pap smear, its transportation to the interpretation centre, its analysis, and the notification of results to users– was estimated in US$ 11.6. If the proposed changes are operated, the cost of each citology would increase by 32.7%. The benefit/cost ratio would be 2 and the net benefit of 88

  11. Currency union entries and trade

    OpenAIRE

    Nitsch, Volker

    2005-01-01

    Recent research suggests that adopting a common currency increases bilateral trade. In this paper, I explore experiences of currency union entry in the post-war period and find no effect on trade. Previous results derived from a large panel data set (covering more than 200 countries from 1948 through 1997) appear to depend crucially on the assumption of symmetry between currency union exits and entries: While countries leaving a currency union experience significant declines in trade, currenc...

  12. Official Union Time Tracking System

    Data.gov (United States)

    Social Security Administration — Official Union Time Tracking System captures the reporting and accounting of the representational activity for all American Federation of Government Employees (AFGE)...

  13. La carga global del cáncer (The Global Cancer Burden)

    Centers for Disease Control (CDC) Podcasts

    2012-02-02

    Este podcast describe la carga global del cáncer y los esfuerzos de los CDC y otras entidades para reducir esa carga.  Created: 2/2/2012 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 3/13/2012.

  14. Radiotherapy effect in conservation treatment for breast cancer. Efecto de la radioterapia sobre los resultados esteticos del tratamiento conservados del cancer de mama

    Energy Technology Data Exchange (ETDEWEB)

    Sachini, V; Ferreri, A J.M.; Farante, G; Agresti, R; Galimberti, V; Zurrida, S; Veronesi, P [Instituto Nazionale per los Studio e la Cura dei Tumori, Milan (Italy)

    1994-01-01

    Radiotherapy (RT) in conservative treatment for breast cancer (CT-BC) has been proven to be determinant for the local control of the disease. Radiation therapy is an important factor affecting the cosmetic results of this treatment. Technical progress in RT, use of filters and wedges and an increased knowledge of the influence of fraction size total dose and irradiated volume on breast tissues contributed to avoid major radiotherapeutic side effects in the CT-BC. Cosmetic outcome from 2 groups of patients (pts) with breast cancer in stage T 1-2(T> = 2,5 cm) N 0-1 M o0 of the prospective trial Milan III were compared. Both groups pts (n=89) were treated with quadrantectomyand axillary dissection. 49 pts received complementary RT with a dose of 50 Gy over 5 weeks with a daily fraction of 2 Gy and a further boost of 10 Gy (10 MeV electrons) on the scar. Remaining 40 pts did not receive RT. Cosmetic results were evaluated. No significant cosmetic differences were observed. A good or excellent symmetry was observed in 59% of irradiated pts and 64% of non irradiated pts. Negative results were observed in 4% and 2% respectively. Subjective ovulation showed similar results, with a good or excellent symmetry in 57% of irradiated pts and 72.5% of non irradiated pts. Poor results were observed in 16.3% and 27.5% respectively. Telangiectasia were observed in 4% of irradiated pts, while hypertrophied scars were only noted in non irradiated pts (15%). No acute side effects of RT, as erythema or ulceration of breast skin, were recorded. In our experience, the standard dose of 50 Gy administered by two opposite tangential fields plus a 10 Gy boost did not affect the cosmetic results of CT.BC, whereas it provided a better local control of disease. The possibility to avoid RT in selected group of pts should be justified by the discomfort of this treatment for the pt, cost analysis and lack of RT centers around the world rather cosmetic reasons. (Author)

  15. Tools for building Breast Cancer CAD methods; Herramientas para elaborar metodos de CAD del cancer de mama

    Energy Technology Data Exchange (ETDEWEB)

    Diaz-Herrero, G.; Franco-Valiente, J. M.; Suarez-Ortega, C.; Rubio del Solar, M.; Ramos-Pollam, R.; Guevara-Lopez, M. A.; Gonzalez de Posada, N.; Ramos, I.; Loureiro, J.

    2011-07-01

    This paper describes the main results of the collaboration currently ongoing between CETA-CIEMAT and the Faculty of Engineering at the University of Porto. It introduces the Mammography image Workstation for Analysis and Diagnosis (MIWAD) and the data analysis processes through which Grid infrastructures are used to develop Breast Cancer Computer-Aided Diagnosis (CAD) methods.MIWAD is a novel integrated software framework that integrates a specialized graphical user interface combining digital image processing, pattern recognition and artificial intelligence techniques. This paper describes its successful application in a pilot experience, on the first Portuguese Breast Cancer Digital Repository. (Author)

  16. Photodynamic Therapy, a new approach in the treatment of oral cancer Terapia Fotodinámica, un nuevo acercamiento en el tratamiento del cáncer oral

    Directory of Open Access Journals (Sweden)

    Leandro Santos Bicalho

    2010-08-01

    Full Text Available The worldwide incidence of head and neck cancer is, approximately, 640,000 new cases per year. Oral cancer accounts for one third of all cancers and it is the eighth most diagnosed in men. The most used treatments for these tumors are surgery, radiotherapy, chemotherapy, or a combination of these therapeutic modalities. Due to the large structural, functional and aesthetic impairment that conventional treatments cause, many studies seek new methods to replace or to assist the treatment of oral cancer. Photodynamic therapy (PDT is a promising new modality of cancer treatment that is already being used clinically. This article describes the use of PDT as an alternative for the treatment of oral cancer. Salud UIS 2010; 42: 167-174.La incidencia del cáncer de cabeza y cuello es aproximadamente 640.000 casos nuevos por año. El cáncer oral representa un tercio de todos los cánceres y es el octavo más diagnosticado en hombres. Los tratamientos más usados para estos tumores son la cirugía, radioterapia, quimioterapia, o una combinación de estas modalidades terapéuticas. Debido al gran deterioro estructural, funcional y estético que causan los tratamientos convencionales, muchos estudios buscan nuevos métodos para remplazar o asistir el tratamiento del cáncer oral. La terapia fotodinámica (PDT es una nueva modalidad promisoria en el tratamiento del cáncer que apenas está siendo usada clínicamente. Este artículo describe el uso de PDT como una alternativa para el tratamiento del cáncer oral. Salud UIS 2010; 42: 167-174

  17. European Union, 2017

    Directory of Open Access Journals (Sweden)

    Malone Margaret Mary

    2018-02-01

    Full Text Available The year 2017 was eventful for the EU and its member states. Given the widespread Euroscepticism and populism which appeared to be on the rise last year, election results in the Netherlands, France and Germany were greeted with relief and hope for the future. The EU was in an optimistic mood. European Commission President Jean- Claude Juncker used his State of the European Union speech in September to note that the EU had the ‘wind in its sails’ (Juncker, 2017. At the same time, he cautioned that the fair weather conditions would not last long - there was no room for complacency. The EU had to act to protect, empower and defend its citizens. The EU moved forward on a number of policy fronts in the wake of the Brexit vote and also concluded high-profile international trade deals in an effort to fill the vacuum left by the protectionist policies of the Trump administration.

  18. SOCIAL REPRESENTATIONS DEL GYNECOLOGICAL CANCER IN THE KNOWLEDGE OF THE BRAZILIAN NURSING

    Directory of Open Access Journals (Sweden)

    Sílvio Éder Dias da Silva

    2014-02-01

    Full Text Available One is a documentary investigation whose objective to characterize the social representations on the gynecological cancer gifts in theses and dissertations of the Brazilian infirmary in the period from 2001 to 2007. The investigation source was the Bank of Thesis and Dissertations of the Brazilian Association of Infirmary. 51 studies had been identified. The analysis of the dices originated the following thematic categories: Imaginary the Social one of Women in front of the Gynecological Cancer; The daily one of the mastectomizada woman; The gynecological cancer and its treatment; Prevention of the gynecological cancer in the vision of the infirmary. The studies caused to apprehend the aspects of the psycho-social context, so important and necessary in the sense more atenciosamente to watch the welfare practice of the infirmary.

  19. Experience of gynecological braquitherapy in the Instituto Nacional del Cancer of Paraguay

    International Nuclear Information System (INIS)

    Guggiari, G.; Almiron, M.; Guggiari, P.A.; Resquin, T.; Ramos, A.

    2004-05-01

    In April 2002 the first braquitherapy was carried out in the National Cancer Institute. With the support of the IAEA, a remote controlled equipment of braquitherapy of low dose was installed and it was qualified to the all technical staff as well as the visit from expert of USA, Spain, Italy, France, Argentina and Brazil. The first 100 braquitherapy was evaluated in patients with diagnose (dx.) of cancer (cea) of uterine neck and endometry [es

  20. Molecular diagnosis of human papillomavirus in the development of cervical cancer Diagnóstico molecular del virus del papiloma humano en el desarrollo del cáncer cervical

    Directory of Open Access Journals (Sweden)

    Lourdes Gutiérrez-Xicoténcatl

    2009-01-01

    Full Text Available Cervical cancer (CC is a major public health problem in developing countries and its most significant etiological risk factor is infection by the human papillomavirus (HPV. The main approach to date for the prevention of CC has been through screening programs, using the cervical smear (PAP test to detect precursory lesions. The sensitivity and specificity of the PAP smear depend on the skills of the observer to recognize and classify a variety of cellular abnormalities. The development of early diagnoses to detect HPV infection has been a problem as cytology and colposcopy identify the lesion at an advanced stage. Therefore, molecular approaches have become more successful for early CC diagnosis. These molecular techniques recognize HPV DNA sequences by DNA hybridization, PCR-RFLP, hybrid capture and reverse line blot systems. Unfortunately, these systems cannot determine whether the HPV infection is active, latent or persistent. Thus, immunological techniques such as Western blot and ELISA have been designed to follow the immune response against the virus, and they can also be used to identify the stage of the infection. Several companies have developed, manufactured and merchandised gene-based testing systems for the screening, monitoring and diagnosis of HPV. Our review and comments focus on the critical analysis of existing products and their use in clinical practice as well as on immunological systems used mainly in research, but that may be applied in large population screening programs.El cáncer cervical (CC es el mayor problema de salud pública en países en vías de desarrollo, al ser la infección por el virus del papiloma humano (HPV el factor etiológico más importante de esta enfermedad. Actualmente, el principal acercamiento para la prevención del CC ha sido a través de programas de detección oportuna del cáncer, lo cual se ha realizado a través del estudio citológico del Papanicolaou (Pap para la detección de lesiones

  1. Phosphorus and Fluorine - The Union for Bioregulators

    Directory of Open Access Journals (Sweden)

    Romanenko, V.

    2007-06-01

    Full Text Available The review demonstrates the very high efficiency and usefulness of the fluorine-phosphorus combination in order to synthesize organic molecules for purposes of modern life science. For biochemistry, the "P-F-union" in" biomolecules enables investigation of the enzyme structure and mechanism of action more correctly, as well as creation of new anti-body enzymes. Enhancing or regulation of inhibitor properties of these compounds, their stability or selectivity allows creation of new drugs for treatment of numerous serious diseases, especially viral infections and cancer.

  2. Professional Employees Turn to Unions

    Science.gov (United States)

    Chamot, Dennis

    1976-01-01

    White-collar and professional employees are increasingly turning to unions to combat their loss of independence as employees of large organizations. Managers should realize that they and professional employees have different viewpoints about job situations and that the current trend toward white-collar unionism is apt to continue. (JG)

  3. Is Union Job Dissatisfaction Real?

    Science.gov (United States)

    Hersch, Joni; Stone, Joe A.

    1990-01-01

    A comparison of data from a Eugene, Oregon, worker survey with data from the Quality of Employment Survey found that union job dissatisfaction arises from factors independent of wages and working conditions. Union perspectives of working conditions do not accurately reflect objective measures of conditions. The dissatisfaction expressed has real…

  4. Grassmann codes and Schubert unions

    DEFF Research Database (Denmark)

    Hansen, Johan Peder; Johnsen, Trygve; Ranestad, Kristian

    2009-01-01

    We study subsets of Grassmann varieties over a field , such that these subsets are unions of Schubert cycles, with respect to a fixed flag. We study such sets in detail, and give applications to coding theory, in particular for Grassmann codes. For much is known about such Schubert unions with a ...

  5. Toward a More Perfect Union

    Science.gov (United States)

    Schachter, Ron

    2010-01-01

    This article explores school districts such as New Haven (Connecticut) Public Schools, whose local union is an American Federation of Teachers (AFT) affiliate and where a shared concern for students has trumped the often adversarial union-management relationship. The author discusses what makes the successful contract negotiations headed by David…

  6. Clinic-surgical characterization of the colorectal cancer in inpatients;Caracterizacion clinico quirurgica del cancer colorrectal en pacientes ingresados

    Energy Technology Data Exchange (ETDEWEB)

    Alejo Concepcion, Osvaldo; Castillo Lamas, Libardo; Umpierrez Garcia, Ibis [Hospital Militar Docente ' Dr Mario Munnoz Monroy' , Matanzas (Cuba)

    2009-07-01

    The colorectal cancer presents high incidence. This pathology occupies the fifth place among the neoplasias in both sexes in Cuba. With the objective of characterizing this disease we carried out a descriptive transversal study at the service of General Surgery of the University Military Hospital of Matanzas 'Dr. Mario Munnoz Monroy', in the period from January 2001 to January 2005, studying age, sex, familiar oncological antecedents, presentation form, localization and diagnosis of the tumor, and also the surgical technique used in the treatment. The results showed predominance of the male sex in ages between 60 and 69 years old, different symptoms depending on the localization, predominance of the rectal cancer, and others. It was concluded that there is a delay between the beginning of the symptoms and the diagnosis, considerably diminishing the healing possibilities and survival

  7. Is there a genetic anticipation in breast and/or ovarian cancer families with the germline c.3481_3491del11 mutation?

    Science.gov (United States)

    El Tannouri, R; Albuisson, E; Jonveaux, P; Luporsi, E

    2018-01-01

    The aim of the current analysis is to evaluate any differences of breast or ovarian cancer age at diagnosis between mothers and daughters carrying the c.3481_3491del11 mutation in the BRCA1 gene. A study cohort of 38 women carrying the c.3481_3491del11 mutation and affected by first breast or ovarian cancer who reported a first breast or ovarian cancer in their mother carrying the c.3481_3491del11 mutation, was identified in 37 different families including members with breast and/or ovarian cancer at the Oncology Institute of Lorraine. Twelve mothers underwent genetic testing. Twenty-five pairs of the 38 mothers-daughters pairs with c.3481_3491del11 mutation were affected by breast cancer and 13 pairs by ovarian cancer. Clinical and genetic data were collected from medical files and family pedigrees. Analyses were conducted for each cancer type. We investigated an early breast cancer detection effect due to early screening programs and also an increased breast tumor aggression. Since major improvements in breast cancer clinical management and imaging techniques appeared after 1980, we compared the age at breast cancer diagnosis and the age at death in mothers and daughters before and after 1980, first, in the group of women including mothers and daughters taken together and then in mothers and daughters separately. The mean age at breast cancer diagnosis was 45.28 ± 10.27 years in mothers and 39.80 ± 7.79 years in daughters (p = 0.026). The difference of age at ovarian cancer diagnosis in mother-daughter pairs was 8.62 ± 12.76 years (p = 0.032). When considering the group of women including mothers and daughters taken together, no significant difference of age at breast cancer diagnosis was found between women affected before 1980 and those affected after 1980 (p = 0.577). However, the age at death increased in these women after 1980 (p = 0.026). Comparison of age at breast cancer diagnosis in mothers and daughters separately

  8. Regulación del ciclo celular y desarrollo de cáncer: perspectivas terapéuticas Relationship between cell cycle and cancer development: Therapeutical approaches

    Directory of Open Access Journals (Sweden)

    OSCAR PERALTA-ZARAGOZA

    1997-09-01

    Full Text Available Durante el proceso de transformación de las células normales a células cancerosas, ocurren varias alteraciones genéticas. En este proceso se presenta la pérdida del control de los mecanismos de replicación y reparación del ADN, así como de la segregación del material genético. Aunque las células normales tienen estrategias de defensa contra el desarrollo del cáncer, las células tumorales activan diferentes vías de escape que permiten la progresión de la neoplasia. Avances recientes han permitido enfocar la investigación del cáncer hacia la identificación de algunos de sus factores etiológicos. El estudio del ciclo celular y su regulación han permitido conocer cómo la fidelidad y la integridad de la replicación del genoma son mantenidas por las funciones coordinadas de los puntos de control y de los sistemas de reparación del ADN. El funcionamiento adecuado de estos procesos puede ser alterado por mutaciones genéticas. Estos hallazgos sugieren que los mecanismos moleculares de regulación que participan en la transformación celular pueden ser empleados como sistemas potenciales para instrumentar nuevas terapias contra el desarrollo del cáncer.Several genetic alterations occur during the transformation process from normal to tumor cells, that involve the loss of fidelity of processes as replication, reparation, and segregation of the genomic material. Although normal cells have defense mechanisms against cancer progression, in tumor cells different escape pathways are activated leading to tumor progression. Recent advances have permitted cancer research to focus on the identification of some of its etiological factors. The knowledge of cell cycle reveals a precise mechanism achieved by the coordinated interactions and functions of cyclin-dependent kinases, control checkpoint, and repair pathways. Furthermore, it has been demonstrated that this coordinated function can be abrogated by specific genetic changes. These

  9. Comportamiento del diagnóstico precoz del cáncer de mama y cérvicouterino en el municipio Cienfuegos Performance of Early Diagnosis of Breast and Cervical Cancer in the Municipality of Cienfuegos

    Directory of Open Access Journals (Sweden)

    Julio Padrón González

    2013-06-01

    Full Text Available Fundamento: el cáncer de mama y cérvicouterino están entre las más frecuentes causas de muerte en la población femenina. Su diagnóstico está entre los programas priorizados del Sistema de Salud Pública. Objetivo: describir el comportamiento del Programa del Cáncer de Mama y de Cuello Uterino en el municipio de Cienfuegos. Métodos: estudio descriptivo y transversal que se realiza en el marco del proyecto CARMEN y comprende el periodo 2010-2011. Se tomó una muestra aleatoria, estratificada al azar. Se analizaron variables como: edad, estado civil, color de la piel, visita de profesionales de la salud, dominio sobre el autoexamen de mama, examen clínico de las mamas, mamografía, prueba citológica y tiempo transcurrido desde el último chequeo de cada una de las pruebas. Se utilizó el cuestionario del estudio CARMEN. Para el análisis de los resultados se utilizó el paquete estadístico SPSS versión 15,00. El nivel de significación estadístico que se utilizó fue del 95 %. Resultados: un total de 428 mujeres (41,1 % llevaban más de un año sin ser chequeadas y de ellas 49 (4,6 % llevaba más de cinco años. El 71,2 % de la muestra estudiada nunca se ha realizado una mamografía, del 28,6 % que se las ha realizado. El 91,0 % de las mujeres en las edades comprendidas en el Programa alguna vez se ha hecho la prueba citológica. Conclusiones: no se alcanzan los propósitos establecidos por el Programa Integral para el Control del Cáncer en Cuba. Quedan demostradas las áreas de insuficiencias del Programa de Control del Cáncer de Mama y de Cuello Uterino.Background: breast and cervical cancer are among the most frequent causes of death in women. Therefore, the early detection of these diseases is one of the prioritized programs of the Public Health System. Objective: to describe the performance of the Breast and Cervical Cancer Program in the municipality of Cienfuegos. Methods: a cross-sectional descriptive study was conducted

  10. CARACTERIZACIÓN FISICOQUÍMICA Y ACTIVIDAD ANTIMICROBIANA DEL PROPÓLEOS EN EL MUNICIPIO DE LA UNIÓN (ANTIOQUIA, COLOMBIA PHYSICOCHEMICAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF PROPOLIS FROM MUNICIPALITY OF LA UNION (ANTIOQUIA, COLOMBIA

    Directory of Open Access Journals (Sweden)

    Lady Rossana Palomino García

    2010-06-01

    Full Text Available El propóleo un producto natural elaborado por las abejas melíferas (Apis mellifera a partir de los brotes y exudados de diferentes plantas, se ha empleado en la medicina tradicional desde tiempos ancestrales, debido a sus propiedades biológicas. La composición química de este producto de la colmena es altamente compleja y dependiente de la vegetación circundante al sitio de recolección. En este trabajo, se evaluaron las características fisicoquímicas, y la actividad antifúngica y antibacteriana del propóleo colectado en el municipio de La Unión (Antioquia, Colombia. Los resultados del análisis fisicoquímico del propóleo fueron: punto de fusión, 67-68 °C; sustancias extractables con hexano, 74,32 ± 0,90%; resinas solubles en etanol, 14,08 ± 2,24%; residuos insolubles, 10,47 ± 0,84%; pérdidas por calentamiento, 1,82 ± 0,32%; cenizas, 0,16 ± 0,01%, y el índice de oxidación, 8,0 ± 3,0 s. Las evaluaciones de actividad antifúngica, contra los hongos Colletotrichum gloeosporioides, C. acutatum, Aspergillus sp. y Penicillium sp., y de actividad antibacteriana, contra Bacillus subtilis (esporulada, Escherichia coli, Staphylococcus aureus y Salmonella tiphy, demuestran un efecto moderado del propóleo en la inhibición del crecimiento del microorganismo. El análisis mediante cromatografía de gases-espectrometría de masas (CG-EM, permitió la detección de ácidos grasos y sus ésteres, esteroides, triterpenos y diterpenos.Propolis, a natural product collected by honeybees (Apis mellifera from certain plant resins, has been used in folk medicine since ancient times, due to its many biological properties. The chemical composition of this hive product is very complex and depends upon the vegetation of the area from where it was collected. In this work, physicochemical characteristics, and antifungal and antibacterial activity of propolis collected in the municipality of La Unión (Antioquia, Colombia were evaluated. Results of

  11. Study of the 6-n-propyl-2 thiouracil (PTU) as radioprotector in the thyroid cancer; Estudio del 6 propil-2 tiouracilo (PTU) como radioprotector en el tratamiento del cancer de tiroides

    Energy Technology Data Exchange (ETDEWEB)

    Perona, Marina; Dagrosa, Maria A; Pisarev, Mario A; Juvenal, Guillelrmo J [Comision Nacional de Energia Atomica, General San Martin (Argentina). Dept. de Radiogiologia; Pagotto, R; Pignataro, O [Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Buenos Aires (Argentina). Instituto de Biologia y Medicina Experimental; Casal, M [Instituto Nacional de Oncologia ' Angel H. Roffo' , Buenos Aires (Argentina)

    2007-07-01

    epidemiologicos han demostrado que la exposicion a altas dosis de radiacion externa incrementa la frecuencia de neoplasias de tiroides, particularmente cuando la misma ocurre en la niniez o en la adolescencia. El uso de radioprotectores de la tiroides seria de utilidad para evitar efectos tumorigenicos en la glandula cuando la radiacion ionizante en la zona del cuello es la unica terapia posible. Objetivos: Estudiar el posible efecto radioprotector de la droga antitiroidea 6 propil-2 tiouracilo (PTU). Se cultivaron celulas tiroideas normales (linea FRTL-5 de rata) y patologicas (lineas de cancer humano tiroideo anaplasico ARO). Las mismas fueron irradiadas con una fuente de 60Co (1Gy/min) en dosis variables entre 1 y 8 Gy, en presencia y ausencia de PTU (1 mM). A posteriori se evaluo el danio post radiacion mediante el ensayo de formacion de colonias tomando la fraccion de sobrevida (FS) como indicador del efecto. Resultados: La FS aumento respecto del Control en ambas lineas celulares para todas las dosis utilizadas. La relacion PTU vs. Control fue de 2,3 y 2,7 para las celulas ARO y FRTL-5 respectivamente. El efecto radioprotector del PTU es el mismo si es agregado 24 hs antes o inmediatamente post irradiacion. Dado que se ha demostrado que el aumento de la radioresistencia de los tejidos puede inducirse mediante la estimulacion de las vias del AMP ciclico (cAMP), se midieron los niveles del segundo mensajero luego de incubar las lineas celulares durante 5, 24, 48 y 72 horas con diferentes concentraciones de PTU (0; 0,1 mM; 1 mM y 2 mM). El PTU aumento los niveles intra y extracelulares del cAMP en todos los tratamientos. Se observo un pico a las 24 hs en los niveles extracelulares incubados con PTU 1 mM de 36,97 {+-} 6,37 (fmol/{mu}g de prot) vs Control 16,67 {+-} 3,92 (fmol/{mu}g de prot). El efecto radioprotector del PTU fue mimetizado por el cAMP. Conclusion: El PTU ejerce un efecto radioprotector estimulando la via del cAMP. (autor)

  12. La legislazione vaticana in materia finanziaria: un banco di prova dell’art. 17 del TUE e dei principi di collaborazione e cooperazione tra Chiese, Stato e Unione Europea

    Directory of Open Access Journals (Sweden)

    Maria Cristina Folliero

    2013-11-01

    Full Text Available Contributo sottoposto a valutazioneSOMMARIO: 1. Premessa – 2. Antefatti e pre-condizioni della legislazione finanziaria vaticana più recente - 3. Il nuovo corso della legislazione finanziaria vaticana: ruolo e funzione dell’art. 17 del Trattato di Lisbona - 4. Chiese e processo di integrazione valoriale europeo - 5. Chiese e processo mercatista di integrazione economica europea - 6. Il processo di integrazione al modello europeo della legislazione finanziaria vaticana - 7. Un processo che continua.

  13. Enfermagem e Sindicalismo em Goiás: análise do período 1982-2004 Enfermería y Sindicalismo en Goiás: análisis del período 1982-2004 Nursing and Unionism in Goiás: analysis of the period from 1982 to 2004

    Directory of Open Access Journals (Sweden)

    Viviane Lemes da Silva Carvalho

    2007-04-01

    Full Text Available Estudos sobre Sindicalismo e Enfermagem são bastante escassos no Brasil. Em Goiás, só encontramos uma monografia acerca do tema, o que nos levou a examinar a questão. Este trabalho tem como objetivo analisar o sindicalismo na área de enfermagem em Goiás, buscando reconstituir sua trajetória e evidenciar a ocorrência de articulações com outros sindicatos. A metodologia empregada (qualitativa embasa-se na História Nova, com o emprego de fontes primárias (entrevistas e documentos originais e secundárias. As respostas obtidas demonstraram que alguns sindicatos são mais atuantes que outros e que as diferentes possibilidades de afiliação contribuem para enfraquecer o Sindicato dos Enfermeiros de Goiás.Estúdios con respecto al Sindicalismo y Enfermería son bastante raros en el Brasil. En Goiás, sólo encontramos una monografia acerca del tema, lo que nos llevou a examinar esta cuestión. Este trabajo tiene como objetivo analizar el sindicalismo en la área de la enfermería en Goiás, procurando reconstruir su trayectoria y evidenciar la ocurrencia de las articulaciones con otros sindicatos. La metodología utilzada basease en la Historia Nueva, con lo empleo de fuentes primarias y secundarias. Las respuestas obtenidas demonstráron que algunos sindicatos son más actuantes que otros y que las diferentes posibilidades de filiación contribuyen para debilitar el Sindicato de los Enfermeros de Goiás.Studies about Unionism and Nursing are rare in Brazil. In Goiás, we just find out a monograph about the subject, which made us to analyze the question. The objective of this work is to analyze the Unionism of Nursing in Goiás, in search of rebuilt their trajectory and evidence the articulation with others syndicates. The methodology used called "qualitative" based on New History, using primary sources (interview and originals documents and secondary. The answers we have got showed that some syndicates are much skilled than others and

  14. The Energy Union

    International Nuclear Information System (INIS)

    Auverlot, Dominique; Beeeker, Etienne; Hossie, Gaelle; Bettzuege, Marc Oliver; Helm, Dieter; Roques, Fabien

    2015-08-01

    A synthesis of contributions is firstly proposed in this collective publication. In this synthesis, the authors describes the crisis faced by European energy (economic crisis, closure of some thermal power plants due to a lack of profitability, increase of electricity prices, low CO 2 quota prices resulting in a greater use of coal, an ageing refinery system, dependence on the Russian gas for some countries), identify four principles which could be used as guidelines for the European policy (responsibility, solidarity, economic rationality, resilience), define seven recommendations as objectives of a European energy policy. Then, the contributions address the following topics: security of electricity supply, security of European Union's gas supply called into question again, reforming the ETS market to strengthen the credibility of the European climate policy, a necessary evolution of the European energy and climate policy, the issue of a definition of a European energy policy as a dogma or a strategy, the challenge for building up a sustainable and consistent European energy and climate policy

  15. The State of the Union

    DEFF Research Database (Denmark)

    This special issue of Angles marks the three hundredth anniversary of the Union of the two kingdoms of Scotland and England. The nature and development of the relations between the constituent parts of the United Kingdom is a fascinating topic also to outside observers, and some of the contributi...... of the contributions to this volume deal with the Union in a comparative European context. Both Scottish nationalism and Scottish unionism are analysed, and Anglo-Scottish relations are looked at from historical, sociological, linguistic and literary angles...

  16. Metilación del receptor de la hormona estimulante del tiroides: marcador diagnóstico de malignidad en cáncer de tiroides Methylation of the thyroid stimulating hormone receptor: diagnostic marker of malignity in thyroid cancer

    Directory of Open Access Journals (Sweden)

    María Teresa Marrero Rodríguez

    2007-12-01

    Full Text Available Se analizó el estado de metilación del promotor del gen para el receptor de la hormona estimulante del tiroides (TSH en el diagnóstico de tumores tiroideos de origen epitelial. El estudio se realizó en tejido tiroideo obtenido de bloques de parafina de diferentes patologías tiroideas (carcinoma papilar, folicular e indiferenciado, y adenomas foliculares. El trabajo se realizó empleando la técnica de modificación del ADN con bisulfito de sodio y el análisis del estado de la metilación del gen RTSH se realizó por el método de reacción en cadena de la polimerasa específica para metilación. Encontramos metilación del promotor para el gen del receptor de TSH en los carcinomas papilares (33 de 40; 82,5 %, en los 10 carcinomas indiferenciados (100 % y en 10 de los 15 carcinomas foliculares analizados (66,6 %. En cambio, no se observó metilación en los 8 adenomas foliculares analizados. Se propone la metilación del gen para el receptor de TSH como un nuevo marcador diagnóstico de malignidad, y una base para emplear agentes desmetilantes conjuntamente con la terapia con radioyodo, en los pacientes con cáncer de tiroides de origen epitelial que no respondan a la terapia.The methylation state of the gene promoter for the receptor of the thyroid stimulating hormone (TSH in the diagnosis of thyroid tumors of epithelial origin was analyzed. The study was conducted in thyroid tissue obtained from paraffin blocks of different thyroid pathologies (papillary, follicular and undifferentiated carcinoma and follicular adenomas. The work was done by using the DNA modification technique with sodium bisulfite, and polymerase chain reaction was applied to analyze the gene methylation state. Methylation of the promoter for the gene of the TSH receptor was found in the papillary carcinomas (33 of 40; 82.5 %, in 10 undifferentiated carcinomas (100 %, and in 10 of the 15 follicular carcinomas analyzed (66.6 %. No methylation was observed in the 8

  17. Skin cancer prevention and detection campaign at golf courses on Spain's Costa del Sol.

    Science.gov (United States)

    del Boz, J; Fernández-Morano, T; Padilla-España, L; Aguilar-Bernier, M; Rivas-Ruiz, F; de Troya-Martín, M

    2015-01-01

    Skin cancer prevention and detection campaigns targeting specific groups are necessary and have proven to be more effective than those aimed at the general population. Interventions in outdoor tourist spots have proven successful, although none have specifically targeted golf courses. The aims of this study were to describe the risk profile of golfers and golf course workers and evaluate the impact of a skin cancer prevention and early detection intervention. This was a cross-sectional descriptive study conducted at 6 golf courses. The intervention included a skin examination and completion of a questionnaire about demographic details, risk factors, and sun exposure and sun protection habits. Participants were also given advice on sun protection measures, self-examination, and use of sunscreens, and were asked about their satisfaction with the intervention and their intention to change their current behaviors. The effect was measured in terms of the diagnoses made, satisfaction with the intervention, reported intention to change, and potential effect in terms of existing risk factors. Of the 351 participants (57% golfers and 43% golf course workers), 70.4% had fair skin, 11.7% had a family history of skin cancer, and 8.5% had a personal history of skin cancer. Skin cancer and actinic keratoses were diagnosed in 10.7% and 40% of the golfers, respectively. The session was rated positively by 99.4% of the participants; 93.9% stated that they intended to improve their sun exposure habits and 93.4% said that they planned to examine their skin more frequently. Our findings confirm that golf course workers and, in particular, golfers are an important target for skin cancer prevention campaigns. This is the first intervention to specifically target golf courses, and it proved to be both feasible and useful. Its success appears to be attributable to numerous factors: it was conducted at golf courses, had multiple components, and was preceded by a motivational campaign

  18. The Soviet Union

    International Nuclear Information System (INIS)

    Lynch, A.

    1991-01-01

    William T. R. Fox's pre-nuclear age analysis provides an excellent starting point for the authors' discussion of the role of nuclear weapons in Soviet security policy. By pointing to some of the non-nuclear, more properly geopolitical sources of peace in East-West relations, Fox's forceful analysis serves as a reminder to approach the authors' study with caution. Too often, there has been a tendency to reduce the etiology of war and peace in East-West relations to its nuclear aspect without proper regard for other, primarily geopolitical, components which provide the all-important context in which nuclear weapons work their indisputable deterrent effect. Two geopolitical sources for the relative peace in post-war East-West relations have been the inability of either the Soviet Union or the United states to employ direct military force in politically significant terms against the vital interests of the other; and an abiding preference, on the part of both, for a divided Germany within a divided Europe. Any other plausible alternative, of course, would almost certainly have involved a united Germany and the related likelihood that it would either gravitate to one or the other alliance or, itself, would constitute the third leg of an intrinsically unstable tri-polar relationship. This paper reports that the prevailing inclination to analyze East-West security as a direct function of nuclear deterrence (witness the Western consternation about INF and denuclearization, and the proliferation of think-tank study groups on post-nuclear security) begs the probability that there are in fact a variety of deeply rooted structures of stability in East-West relations and so exaggerates the delicacy of the existing security order in Europe. to an extent, this follows form the general acceptance of deterrence theory in the West, especially in the United States, and the undoubtedly singular character and role of nuclear weapons in that order

  19. European Union Energy Research

    International Nuclear Information System (INIS)

    Valdalbero, D.R.; Schmitz, B.; Raldow, W.; Poireau, M.

    2007-01-01

    This article presents an extensive state of the art of the energy research conducted at European Union level between 1984 and 2006, i.e. from the first to the sixth European Community Framework Programmes (FP1-FP6) for Research, Technological Development and Demonstration (RTD and D). The FP is the main legal tool and financial instrument of EU RTD and D policy. It sets the objectives, priorities and budgets for a period of several years. It has been complemented over time with a number of policy oriented initiatives and notably with the launch of the European Research Area. FP7 will cover the period 2007-2013 and will have a total budget of more than euros 50 billion. Energy has been a main research area in Europe since the founding Treaties (European Coal and Steel Community, European Atomic Energy Community-Euratom and European Economic Community), and energy RTD and D has always been a substantial part of common EU research. Nevertheless, when inflation and successive European enlargements are taken into account, over time the RTD and D effort in the field of energy has decreased significantly in relative terms. In nominal terms it has remained relatively stable at about euros 500 million per year. For the next years (FP7), it is expected that energy will still represent about 10 % of total EU research effort but with an annual budget of more than euros 800 million per year. This article presents a detailed review of the thematic areas and budget in both European nuclear energy research (fusion and fission) and non-nuclear energy research (energy efficiency/rational use of energy, fossil fuels, CO 2 capture and storage, fuel cells and hydrogen, renewable energy sources, strategic energy research/socio-economy). (authors)

  20. European Union: US Hegemonic Competitor

    National Research Council Canada - National Science Library

    Kellar, Ronald

    2001-01-01

    .... Intergovernmentalism in the European Community has evolved into an economic form of supranationalism with the persona change form Community to Union after ratification of the Treaty of Maastricht in 1993...

  1. Public Sector Unions and Privatization

    DEFF Research Database (Denmark)

    Foged, Søren Kjær; Aaskoven, Lasse

    2016-01-01

    Privatization varies considerably among local governments. One of the oft-listed explanations is the ability of public employees to block privatization. However, many studies on the influence of public employees on privatization do not use very precise measures of the influence of public employees...... Danish municipalities in 2012, we are able to measure the strength of the public eldercare union as well as the number of the public eldercare workers relative to the number of local voters. We find that the increased union strength measured in terms of union density at the municipal level leads...... to substantially and significantly less privatization through the voucher market. By comparison, the estimated relationship between the relative number of public workers and privatization does not reach statistical significance. Features of the voucher market and qualitative evidence suggest that the union...

  2. Brexit and the European Union

    DEFF Research Database (Denmark)

    Jensen, Mads Dagnis; Snaith, Holly

    2018-01-01

    When on 23 June 2016 a majority voted in favour of the United Kingdom (UK) leaving the European Union (EU), it generated a host of unknowns. Prior to the referendum, scholars had already started to anticipate the implications of a potential Brexit from different perspectives, including considering...... lie and suggesting where Britain’s exit will leave the greatest strategic vacuums. The subsequent analysis centres on the actors that will likely win and lose from the UK’s exit from the Union....

  3. Coordination in the European Union

    OpenAIRE

    Martin Feldstein

    2013-01-01

    This paper examines the sources of current conflict within the EU and the EMU. The topics discussed include the recent ECB policy of bond buying (the OMT policy), the attempts to advance the "European Project" of stronger political union (the fiscal compact, the banking union, and the proposals for budget supervision). Contrary to the claims of the European leadership, the progress that has been made has been by individual countries and not by coordinated action. The special problems of Franc...

  4. A convivência com o fantasma do câncer Viviendo con el fantasma del cancer Coping with the specter of cancer

    Directory of Open Access Journals (Sweden)

    Maria Aparecida Salci

    2010-03-01

    Full Text Available A proposta deste estudo é compreender como mulheres com câncer e seus familiares convivem e enfrentam a doença após o término do tratamento. Como estratégia teórico-metodológica foi utilizado o Interacionismo Simbólico e a Teoria Fundamentada nos Dados. Os dados foram coletados no período de março a novembro de 2005, junto a vinte indivíduos, sendo dez mulheres portadoras de câncer e seus familiares, os quais constituíram três grupos amostrais. Identificamos que conviver com o câncer desencadeia uma série de emoções, entre elas, o medo de que um dia uma recidiva possa se instalar, o que torna a realização de exames pós tratamento algo consideravelmente estressante. Conviver com o câncer significa preocupar-se com ele e buscar estratégias para uma boa convivência. O estudo nos permite compreender esse contexto e repensar algumas estratégias de cuidados a partir dessas considerações.El objetivo de este estudio es entender cómo las mujeres y sus familias viven con el enfrentamiento diario de cáncer después del tratamiento. Como estrategia teórico y metodológica se utilizó el Interaccionismo Simbólico y la Teoría Fundamentada en los datos. Los datos fueron recolectados a partir de marzo a noviembre de 2005, con veinte individuos, diez mujeres que sufren de cáncer y sus familiares, divididos en tres grupos. Convivir con el cáncer desencadena una variedad de emociones, entre ellas el temor de que un día a la recaída puede ser instalado, lo que hace que las pruebas de laboratorio después del tratamiento sean algo bastante estresante. Vivir con el cáncer significa preocuparse con él y buscar estrategias para una buena vida. El estudio nos permite comprender esto contexto y reflexionar sobre algunas estrategias para la atención de estas consideraciones.The purpose of this study is to understand how women and their families live with the daily confrontation of cancer after the end of the treatment. Symbolic

  5. Why do people join trade unions?

    DEFF Research Database (Denmark)

    Toubøl, Jonas; Jensen, Carsten Strøby

    level on union recruitment, which is not done before. Workplace union density is taken to measure the strength of the workplace’s custom of being union member creating an instrumental incentive to join the union. Self-placement on a political left-right scale measures political attitude taken...

  6. Análisis costo beneficio del Programa de Detección Oportuna del Cáncer Cervicouterino Cost benefit analysis of the Cervical Cancer Screening Program

    OpenAIRE

    PATRICIA HERNÁNDEZ-PEÑA; EDUARDO CÉSAR LAZCANO-PONCE; PATRICIA ALONSO-DE RUIZ; AURELIO CRUZ-VALDEZ; FERNANDO MENESES-GONZÁLEZ; MAURICIO HERNÁNDEZ-AVILA

    1997-01-01

    Objetivo. Determinar el costo beneficio de la reorganización del Programa de Detección Oportuna del Cáncer Cervicouterino (PDOC) mediante intervenciones de garantía de calidad. Material y métodos. Se siguieron tres etapas: a) identificación y cuantificación de costos; b) identificación y cuantificación de beneficios, y c) evaluación económica del costo beneficio. Resultados. El costo unitario de operación por citología -obtención, fijación, el traslado al centro de lectura, su tinción e inter...

  7. Cervical cancer and human papillomavirus: Epidemiological evidence and perspectives for prevention Cáncer del cérvix y virus del papiloma humano: evidencia epidemiológica y perspectivas para su prevención

    Directory of Open Access Journals (Sweden)

    NUBIA MUÑOZ

    1997-07-01

    Full Text Available Cervical cancer is a major public health problem, as it is the second most common cancer in women world-wide after breast cancer. About 80% of the half a million cases estimated to occur annually in the world, occur in developing countries. The epidemiological evidence linking human papillomavirus (HPV to cervical cancer is reviewed. It is concluded that over 90% of cervical cancers can be attributed to certain HPV types. HPV 16 accounts for the highest proportion (50% followed by HPV 18 (12%, HPV 45 (8% and HPV 31 (5%. The associations with these HPV types are very b and consistent with odds ratios over 15 in all case-control studies in high- and low-risk countries for cervical cancer. However, HPV is not a sufficient cause of this malignancy; certain cofactors are necessary for a proportion of HPV persistent infections to eventually progress to cancer. These include host factors such as histocompatibilidad types and immunological response, hormonal influences and infections with other sexually transmitted agents such as Chlamydia trachomatis. In addition, results from our studies carried out in Spain and Colombia support the hypothesis that male carriers of HPV play an important role in the development of cervical cancer in their wives. The recognition of the central role of HPV in cervical cancer has far-reaching implications for the primary and secondary prevention of this malignancy. Prophylactic and therapeutic HPV vaccines are now under development and HPV typing is being integrated into screening programmes in pilot studies in a few developed countries. In developing countries, well conducted conventional screening programmes remain the best approach for the control of cervical cancer until a safe and efficient HPV vaccine can be used in the general population.El cáncer del cérvix constituye un problema importante de salud pública y es el más común en el mundo, después del de mama. Aproximadamente 80% de los 500 000 casos que se

  8. Influencia de la cantidad de O2 adicionado al CO2 en el gas de protección sobre la microestructura del metal depositado en uniones soldadas de bordes rectos en aceros de bajo contenido de carbono con el proceso GMAW Influence of O2 content, added to CO2 in the shielding gas, on the microstructure of deposited metal in butt welded joint with straight edges, in low carbon steels using GMAW process

    Directory of Open Access Journals (Sweden)

    Eduardo Díaz-Cedré

    2010-12-01

    Full Text Available La presencia de ferrita acicular (FA en la microestructura del cordón de soldadura, dentro de determinado rango de valores, eleva considerablemente la tenacidad de las uniones soldadas. Es por ello, que el presente trabajo trata sobre un estudio que relaciona la cantidad de ferrita acicular en el cordón en función del contenido de oxígeno presente en la mezcla activa CO2+O2, durante la realización de uniones soldadas de bordes rectos en aceros de bajo carbono con el proceso con electrodo fusible y protección gaseosa (GMAW en condiciones invariables de parámetros de proceso (corriente de soldadura, voltaje de arco, velocidad de soldadura, longitud libre y flujo de gas protector. Como resultado del trabajo se estableció la relación gráfica existente entre la ferrita acicular y el contenido de oxígeno en la mezcla.The presence of acicular ferrite (AF in the microstructure of weld bead, in a specified range of values, increase considerably the toughness of welded joints. The present paper, for that reason, study the relationship between the acicular ferrite quantity in the deposited metal and the oxygen present in the active gas mixture of CO2+O2, during the execution of butt welded joints with straight edges, in low carbon steels with consumable electrode and gas protection (GMAW in invariable conditions of process parameters (welding current, arc voltage, welding speed, electrode extension, and gas flow. The graphic relation between the acicular ferrite and the oxygen content was established, as result of the research work.

  9. Asentamiento diario de megalopas de jaibas del género Cancer en un estuario micromareal Daily settlement of Cancer crab megalopae in a microtidal estuary

    Directory of Open Access Journals (Sweden)

    Luis Miguel Pardo

    2012-03-01

    Full Text Available El asentamiento de crustáceos decápodos en ambientes estuarinos, es la última etapa de un complejo proceso en que las especies meroplanctónicas cierran la fase de vida pelágica. Este proceso tiene etapas sucesivas, que comienza con la formación de parches larvales frente a la costa, su transporte hacia las zonas de crianza, exploración de sustrato en busca de un lugar adecuado para el asentamiento y la metamorfosis a juvenil. Las interacciones entre los factores físicos y el comportamiento de las larvas competentes regulan las diversas etapas de este proceso, determinando finalmente las tasas de asentamiento locales. En este estudio se analiza la importancia relativa de las forzantes físicas que actúan a meso-escala (i.e. estrés del viento, nivel del mar y caudal del río y micro-escala (condiciones locales de temperatura, salinidad y tipo de sustrato sobre el asentamiento de megalopas de los braquiuros Cancer edwardsii y C. coronatus, principales jaibas comerciales en la pesca artesanal chilena. Para esto se instalaron colectores larvales pasivos de fondo por 73 días consecutivos en el periodo de máximo reclutamiento (i.e. abundancia de juvenil I, en la desembocadura del estuario del río Valdivia y se dispuso de arena gruesa y un símil de tapiz algal como sustrato. Los resultados mostraron que: a el asentamiento está caracterizado por extensos periodos de escasos asentados alternados por pulsos de máximos, que no necesariamente coinciden entre las especies estudiadas, b el asentamiento de C. edwardsii mostró estar relacionado con múltiples forzantes que generan la advección de aguas cálidas hacia la costa, c el asentamiento de C. coronatus tuvo relación con las forzantes que generan la surgencia costera, d las larvas de ambas especies no difieren en el asentamiento sobre sustratos heterogéneos. Este estudio mostró que los patrones de asentamiento larval son especie específicos, incluso en especies simpátricas y

  10. New European initiatives in colorectal cancer screening: Budapest Declaration. Official appeal during the Hungarian Presidency of the Council of the European Union under the Auspices of the United European Gastroenterology Federation, the European Association for Gastroenterology and Endoscopy and the Hungarian Society of Gastroenterology.

    Science.gov (United States)

    Wittmann, Tibor; Stockbrugger, Reinhold; Herszényi, László; Jonkers, Daisy; Molnár, Béla; Saurin, Jean-Christophe; Regula, Jaroslaw; Malesci, Alberto; Laghi, Luigi; Pintér, Tamás; Teleky, Béla; Dítě, Petr; Tulassay, Zsolt

    2012-01-01

    Colorectal cancer (CRC) is the second most common newly diagnosed cancer and the second most common cause of death in the European Union (EU). CRC is an enormous health and economic burden. Early detection and prevention have the possibility of reducing this burden significantly. Many cancer-associated deaths can be avoided through early detection by high-quality colorectal screening programs followed by appropriate treatment. Under the auspices of the United European Gastroenterology Federation (UEGF), the European Association for Gastroenterology and Endoscopy, the Hungarian Society of Gastroenterology and the Hungarian College of Gastroenterology, the 'Budapest Declaration' (2011) was an accepted official scientific program during the Hungarian Presidency of the Council of the European Union. The Budapest Declaration follows the Munich Declaration (2001), the Brussels Declaration (2007), the Transatlantic Declaration (2009), the Barcelona Declaration (2010), the written declaration of CRC screening, a joint initiative with European Parliamentarians coordinated by the UEGF, and finally, the 'European Guidelines for Quality Assurance in Colorectal Cancer Screening and Diagnosis'. The 'Budapest Declaration' together with previous declarations aims to urge the national and supranational healthcare decision makers to launch new Europe-wide initiatives to establish high-quality CRC programs to achieve optimal efficiency in CRC screening. In case of implementation of the proposals, actions and conditions recommended, we can achieve that one of the basic principles of the EU - the chance of equal access - be realized in member states with respect to the prevention of CRC and reduction of cancer-related mortality. To better achieve this goal, we propose to establish an UEGF joint committee, with one participant representing each EU member state to coordinate and supervise the implementation of CRC screening. Copyright © 2012 S. Karger AG, Basel.

  11. Tamizaje del cáncer colorrectal Screening for colorectal cancer

    Directory of Open Access Journals (Sweden)

    2002-10-01

    Full Text Available This piece summarizes new recommendations from the Preventive Services Task Force of the United States of America concerning screening for colorectal cancer (CRC. These recommendations update and replace ones that were issued in 1996. The Task Force strongly recommends that physicians carry out CRC screening tests for both men and women who are 50 years of age or older. The Task Force found fair or good evidence that: 1 several screening methods are effective in reducing mortality from CRC, 2 the benefits of screening outweigh its risks, although the quality of the tests, the magnitude of the benefits, and the potential harms vary according to the method, and 3 periodic fecal occult blood testing (FOBT reduces mortality from CRC. In addition, there is fair evidence that sigmoidoscopy, either alone or in combination with FOBT, reduces CRC mortality. There is no direct evidence that screening colonoscopy is effective in reducing CRC mortality, nor is it clear if the greater accuracy of colonoscopy in comparison to other tests compensates for its additional complications, inconvenience, and costs. Double-contrast barium enema is less sensitive than colonoscopy, and there is no direct evidence that it is effective in lowering mortality rates. There are insufficient data to determine which screening strategy is best in terms of the balance of benefits, potential harms, and cost-effectiveness. Regardless of the strategy chosen, CRC screening is likely to be cost-effective (less than US$ 30 000 per year of life gained.

  12. Osteoporosis in the European Union

    DEFF Research Database (Denmark)

    Svedbom, A; Hernlund, E; Ivergård, M

    2013-01-01

    the burden of osteoporosis in each of the EU27 countries in 2010 and beyond. METHODS: The data on fracture incidence and costs of fractures in the EU27 were taken from a concurrent publication in this journal (Osteoporosis in the European Union: Medical Management, Epidemiology and Economic Burden......UNLABELLED: This report describes epidemiology, burden, and treatment of osteoporosis in each of the 27 countries of the European Union (EU27). INTRODUCTION: In 2010, 22 million women and 5.5 million men were estimated to have osteoporosis in the EU; and 3.5 million new fragility fractures were...

  13. Union members at the polls in diverse trade union landscapes

    DEFF Research Database (Denmark)

    Arndt, Christoph; Rennwald, Line

    2016-01-01

    still enjoy important support from trade union members, but at the same time are under fierce competition from bourgeois and green parties among members of white-collar confederations. This reinforces the challenges for social democracy to build new voters’ coalitions in post-industrial societies....

  14. The male role in cervical cancer El papel del varón en el cáncer cervical

    Directory of Open Access Journals (Sweden)

    Xavier Castellsagué

    2003-01-01

    Full Text Available Experimental, clinical, and epidemiological evidence strongly suggests that genital Human Papillomaviruses (HPVs are predominantly sexually transmitted. Epidemiological studies in virginal and HPV-negative women clearly indicate that sexual intercourse is virtually a necessary step for acquiring HPV. As with any other sexually transmitted disease (STD men are implicated in the epidemiological chain of the infection. Penile HPVs are predominantly acquired through sexual contacts. Sexual contacts with women who are prostitutes play an important role in HPV transmission and in some populations sex workers may become an important reservoir of high-risk HPVs. Acting both as "carriers" and "vectors" of oncogenic HPVs male partners may markedly contribute to the risk of developing cervical cancer in their female partners. Thus, in the absence of screening programs, a woman's risk of cervical cancer may depend less on her own sexual behavior than on that of her husband or other male partners. Although more rarely than women, men may also become the "victims" of their own HPV infections as a fraction of infected men are at an increased risk of developing penile and anal cancers. Male circumcision status has been shown to reduce the risk not only of acquiring and transmitting genital HPVs but also of cervical cancer in their female partners. More research is needed to better understand the natural history and epidemiology of HPV infections in men.Evidencia experimental, clínica y epidemiológica demuestra que los papilomavirus humanos (VPH genitales son predominantemente de transmisión sexual. Estudios experimentales en mujeres vírgenes y en mujeres VPH-negativas indican de forma clara que el coito es virtualmente un paso necesario para adquirir el VPH. Como ocurre con cualquier otra infección de transmisión sexual (ITS los varones están implicados en la cadena epidemiológica de la infección. Los VPH en el pene son predominantemente adquiridos a

  15. Factores pronósticos del cáncer de mama Prognostic factors of breast cancer

    Directory of Open Access Journals (Sweden)

    José María González Ortega

    2011-03-01

    Full Text Available Los factores pronósticos se deben diferenciar de los factores predictivos. Un factor pronóstico es cualquier medición utilizable en el momento de la cirugía que correlaciona con el intervalo libre de enfermedad o supervivencia global en ausencia de tratamiento adyuvante sistémico y como resultado es capaz de correlacionar con la historia natural de la enfermedad. En contraste, un factor predictivo es cualquier medición asociada con respuesta a un tratamiento dado. Entre los factores pronósticos del cáncer de mama existen factores clínicos, histológicos, biológicos, genéticos y psicosociales. En esta revisión de los factores pronósticos psicosociales ha quedado demostrado que el estrés y la depresión son factores pronósticos negativos en las pacientes con cáncer de mama. Se debe recordar que la evaluación de un solo parámetro pronóstico ayuda, pero no es útil para la gestión clínica y terapéutica de la paciente.The prognostic factors must to be differentiated of the predictive ones. A prognostic factor is any measurement used at moment of the surgery correlated with the free interval of disease or global survival in the absence of the systemic adjuvant treatment and as result is able to correlate with the natural history of the disease. In contrast, a predictive factor is any measurement associated with the response to a given treatment. Among the prognostic factors of the breast cancer are included the clinical, histological, biological, genetic and psychosocial factors. In present review of psychosocial prognostic factors has been demonstrated that the stress and the depression are negative prognostic factors in patients presenting with breast cancer. It is essential to remember that the assessment of just one prognostic parameter is a help but it is not useful to clinical and therapeutic management of the patient.

  16. On the immunostimulatory hypothesis of cancer Sobre la hipótesis inmunoestimulatoria del cáncer

    Directory of Open Access Journals (Sweden)

    Juan Bruzzo

    2011-12-01

    Full Text Available There is a rather generalized belief that the worst possible outcome for the application of immunological therapies against cancer is a null effect on tumor growth. However, a significant body of evidence summarized in the immunostimulatory hypothesis of cancer suggests that, upon certain circumstances, the growth of incipient and established tumors can be accelerated rather than inhibited by the immune response supposedly mounted to limit tumor growth. In order to provide more compelling evidence of this proposition, we have explored the growth behavior characteristics of twelve murine tumors -most of them of spontaneous origin- arisen in the colony of our laboratory, in putatively immunized and control mice. Using classical immunization procedures, 8 out of 12 tumors were actually stimulated in "immunized" mice while the remaining 4 were neither inhibited nor stimulated. Further, even these apparently non-antigenic tumors could reveal some antigenicity if more stringent than classical immunization procedures were used. This possibility was suggested by the results obtained with one of these four apparently non-antigenic tumors: the LB lymphoma. In effect, upon these stringent immunization pretreatments, LB was slightly inhibited or stimulated, depending on the titer of the immune reaction mounted against the tumor, with higher titers rendering inhibition and lower titers rendering tumor stimulation. All the above results are consistent with the immunostimulatory hypothesis that entails the important therapeutic implications -contrary to the orthodoxy- that, anti-tumor vaccines may run a real risk of doing harm if the vaccine-induced immunity is too weak to move the reaction into the inhibitory part of the immune response curve and that, a slight and prolonged immunodepression -rather than an immunostimulation- might interfere with the progression of some tumors and thus be an aid to cytotoxic therapies.Existe la creencia de que el peor

  17. TOWARDS THE CAPITAL MARKET UNION

    Directory of Open Access Journals (Sweden)

    Iulian PANAIT

    2015-06-01

    Full Text Available This paper discusses the main characteristics of the proposed Capital Markets Union in Europe, as they are introduced by the European Commission and various authors, and emphasises some important advantages and disadvantages of this project for the developing and frontier markets in UE, especially for Romania.

  18. Rationalities in trade union work

    DEFF Research Database (Denmark)

    Buch, Anders; Andersen, Vibeke

    2011-01-01

    The ambition of this paper is to analyze the discursive practices of three Danish trade unions for professional and managerial staff (The Danish Society of Engineers, The Association of Lawyers and Economists, and The Danish Association of Masters and PhD’s) as found in their strategy and positio...

  19. Intersectionality in European Union policymaking

    DEFF Research Database (Denmark)

    Lombardo, Emanuela; Agustin, Lise Rolandsen

    2016-01-01

    is particularly apt to deal with equality and diversity in policymaking. By analysing a selection of European Union policy documents on gender-based violence in the period 2000–2014, we attend to the question of what intersectionality can bring to policymaking in terms of strengthening inclusiveness and address...

  20. On Union-Based Classes.

    Science.gov (United States)

    Forsythe, Linda

    1982-01-01

    A course combining English in the workplace, information seeking and job application skills, occupational safety, and other workplace skills conducted by a community college and a major industrial union is described. The very successful program will be continued and developed based on the initial experience. (MSE)

  1. Rawls and the European Union

    NARCIS (Netherlands)

    Kamminga, Menno R.

    2014-01-01

    Renowned political philosopher John Rawls once expressed skepticism about the moral status of the European Union (EU). Yet generally EU scholars have either ignored Rawls or rather uncritically established positive links between his theory of domestic and international justice and the EU. This

  2. Recursos disponibles para el tratamiento del cáncer de mama en México Available resources for the treatment of breast cancer in Mexico

    Directory of Open Access Journals (Sweden)

    Alejandro Mohar

    2009-01-01

    Full Text Available OBJETIVO: Describir los recursos existentes para el tratamiento del cáncer de mama en México. MATERIAL Y MÉTODOS: Se recolectó información de 23 Centros Estatales de Cáncer (CEC, dos hospitales federales y el Instituto Nacional de Cancerología. Este estudio se realizo en México, DF, en agosto y septiembre del año 2008. RESULTADOS: Los 23 CEC ofrecen atención médica para el cáncer de mama, incluidos cirugía, quimioterapia y radioterapia, todos ellos acreditados por el Seguro Popular. Las cuotas de recuperación se definieron por etapa clínica, desde 27 500 pesos para la etapa clínica cero hasta 480 000 pesos en pacientes con enfermedad avanzada. Se ha atendido a 2 689 pacientes con cáncer de mama; sólo 1% se presentó con carcinoma in situ CONCLUSIONES: Se tiene la infraestructura y los recursos médicos para el óptimo tratamiento, pero los costos son altos debido al diagnóstico tardío. La detección oportuna del cáncer de mama es una prioridad para el óptimo control de esta enfermedad en México.OBJECTIVE: Describe the resources for the treatment of breast cancer in Mexico. METHODS: Information was obtained from 23 Centros Estatales de Cáncer (State Cancer Centers, CEC, two federal hospitals and Cancerología. This study was performed in Mexico City in August/September of 2008. RESULTS: These 23 centers provide medical care for breast cancer including surgery, chemotherapy and radiotherapy; all of them validated by the Seguro Popular. The costs were defined according to clinical stage and ranged from $27,500.00 pesos for clinical stage 0 to $480,00.00 in the advanced stage. A total of 2 689 women with breast cancer have been treated; only 1% was reported with in situ carcinoma. CONCLUSIONS: An adequate medical infrastructure is in place to treat breast cancer in Mexico. The costs are high due to late diagnosis of the disease. Early detection of breast cancer is a high priority for optimal control of this disease in Mexico.

  3. Estadificación y valoración mediastínica del cáncer del pulmón Staging and mediastinal assessment of lung cancer

    Directory of Open Access Journals (Sweden)

    Miguel Emilio García Rodríguez

    2010-12-01

    Full Text Available El cáncer de pulmón se considera la más letal de las neoplasias, tanto en los hombres como en las mujeres, y supera la suma de todas las muertes por cáncer de colon, próstata y mama. En el momento del diagnóstico más del 40 % de los pacientes tienen una enfermedad localmente avanzada, en la que las posibilidades de curación son escasas y la supervivencia a los 5 años es de apenas un 15 %. La estadificación de la enfermedad, así como la valoración mediastínica es crucial para realizar un tratamiento correcto, establecer pronósticos y realizar investigaciones que conlleven a una conducta adecuada ante estos pacientes. Con el objetivo de actualizar el tema se realizó una revisión en varias bases de datos en inglés: Pubmed, Medline y Ebsco, utilizando las palabras clave: lung cancer staging, mediastinal lymphonode excision y lung carcinoma.The lung cancer is considered the most lethal of neoplasias both in men and women and it is the highest figure of all death by colon, prostate and breast deaths. At diagnosis more than the 40% of patients have a locally advanced disease with scarce possibilities of cure and the 5-years survival is hardly of a 15%. Disease's staging as well as the mediastinal assessment is crucial to a proper diagnosis, to establish prognoses and the carry out researches leading to a appropriate behavior in these cases. The objective of present paper was to update on this subject authors made search in some databases in English language: Pubmed, Medline and Ebsco, using lung cancer staging, mediastinal lymphonode excision and lung carcinoma as key words.

  4. Tratamiento quirúrgico del cáncer infiltrante de cuello uterino. Supervivencia Surgical treatment of the infiltrative cervical cancer. Survival rate

    Directory of Open Access Journals (Sweden)

    Vladimir Díaz Noda

    2004-04-01

    Full Text Available El cáncer de cuello uterino ocupa el segundo lugar entre los tipos de cáncer de la mujer y el quinto entre todos los tipos de cáncer que afectan al ser humano. Se realizó un estudio retrospectivo y longitudinal a las pacientes con cáncer infiltrante de cuello uterino que recibieron tratamiento quirúrgico entre los años 1988 y 1993 en el Hospital "Abel Santamaría Cuadrado", de Pinar del Río. Para esta investigación se confeccionó encuesta, que fue aplicada a las 37 pacientes estudiadas; los datos fueron obtenidos de las historias clínicas y el interrogatorio a las pacientes. Las variables estudiadas fueron: edad, número de partos, edad del primer coito y del primer parto y la supervivencia. Entre los principales resultados se encontró que el grupo de edades entre los 40-49 años fue el más frecuente en las pacientes estudiadas, todas las pacientes habían parido, más de la mitad de las pacientes comenzaron las relaciones sexuales antes de los 17 años. La adolescencia predominó como edad del primer parto en las pacientes estudiadas y solo una paciente falleció en este periodo.The cervix cancer takes the second place among the types of cancer in women and the fifth place among all of the types affecting the human being. A retrospective, longitudinal study was performed in patients suffering from infiltrative cervix cancer and they were given surgical treatment between 1988 and 1993 at Abel Santamaría Cuadrado General Hospital in Pinar del Río. A survey was made applying it to 37 patients; data were collected from the clinical records and from the interview to patients. Age, number of deliveries, age at the first coitus and first delivery and survival were the studied variables. It was found that 40-49 year old group was the most frequent among the studied patients, all the patients had given birth, over more than half of patients started sexual relations before 17 years of age. Adolescence prevailed as first - delivery age in

  5. Portfolio Optimization for Multiple Group Credit Unions

    National Research Council Canada - National Science Library

    Willis, John

    1999-01-01

    ...) to diversify, credit unions now have the opportunity to market their services to specific employee groups or industries which can reduce the overall risk to the credit unions' health or solvency...

  6. Gender Differences in Attitudes toward Unions.

    Science.gov (United States)

    Schur, Lisa A.; Kruse, Douglas L.

    1992-01-01

    A 1984 survey of 250 union members (86 women and 164 men) showed that most women, especially those in private sector white collar jobs, were interested in joining unions but face barriers such as family responsibilities. (SK)

  7. Partnership Creates Centre for Union Studies

    Science.gov (United States)

    Smart, Carol; Roman, Stephen

    1978-01-01

    A unique cooperative venture between the city of Coventry and local trade unions is establishing a library collection of books, periodicals, historical documents, tapes, and films dealing with unions, labor studies, and industrial problems. (JAB)

  8. Students Union, University Administration and Political Development ...

    African Journals Online (AJOL)

    Students Union, University Administration and Political Development of Nations. ... African Research Review ... resting on the reciprocal determinism of the social learning theory, that students union makes university administration smooth.

  9. Vaccines against human papillomavirus and perspectives for the prevention and control of cervical cancer Vacunas contra virus del papiloma humano y perspectivas para la prevención y el control del cáncer cervicouterino

    Directory of Open Access Journals (Sweden)

    Alejandro García-Carrancá

    2003-01-01

    Full Text Available Today, "persistent" infections by certain types of human papillomavirus (HPV are considered necessary for developing cervical cancer. Producing efficient vaccines against these viruses may eventually lead to a great reduction in incidence and mortality rates of this cancer. In the case of HPV, the production of traditional vaccines usually based in dead or attenuated viruses is not possible due in part to the lack of systems where large quantities of viral particles could be obtained. Fortunately, the expression of the late L1 protein alone, or in combination with L2, leads to the generation of structures resembling true virions that have been called virus-like particles (VLPs and constitute excellent candidates as prophylactic vaccines. VLPs have shown to be very immunogenic, and have prevented development of natural or challenged infections in both animal systems and humans. Recently, HPV16 VLPs were shown to be very efficient to prevent the development of "persistent" infections, as determined by PCR assays, in a large group of vaccinated women. Therapeutic vaccines, on the other hand, are expected to have an impact on advanced lesions and residual illness, by taking advantaje of the fact that early E6 and E7 genes are thought to be constitutively expressed in cervical tumors and precursor lesions. Finally, DNA-based vaccines could represent a useful alternative for preventing infections by genital HPV.Actualmente, las infecciones "persistentes" por algunos tipos del virus del papiloma humano se consideran como necesarias para desarrollar cáncer cervicouterino. Por ello, el desarrollo de vacunas eficientes contra estos virus se ha considerado de suma importancia para poder eventualmente ayudar a controlar esta enfermedad, en países donde los programas de detección oportuna no han dado aún los resultados deseados. En el caso de estos virus no es posible el desarrollo de vacunas tradicionales, las cuales están basadas generalmente en el

  10. Optimización del proceso de soldadura GMAW de uniones a tope de la aleación AA 6063-T5 basada en la metodología de superficie de respuesta y en la geometría del cordón de soldadura

    Directory of Open Access Journals (Sweden)

    Miguel, V.

    2012-10-01

    Full Text Available The geometry of the weld beads is characterized by the overhead, the width and the penetration. These values are indices of the behavior of the welded joint and therefore, they can be considered as factors that control the process. This work is performed to optimize the GMAW process of the aluminum alloy AA 6063-T5 by means of the response surface methodology (RSM. The variables herein considered are the arc voltage, the welding speed, the wire feed speed and the separation between surfaces in butt joints. The response functions that are herein studied are the overhead, the width, the penetration and the angle of the bead. The obtained results by RSM show high grade of agreement with the experimental values. The procedure is experimentally validated by welding for the theoretically obtained optimized technological conditions and a wide agreement between theoretical and experimental values is found.

    La geometría de los cordones de soldadura es caracterizada por el sobreespesor, la anchura y la penetración. Estos valores son indicadores del comportamiento de la unión soldada por lo que pueden considerarse como factores de control del proceso. En el presente trabajo se efectúa la optimización del proceso de soldadura por arco GMAW de la aleación AA 6063-T5 mediante la metodología de la superficie de respuesta (MSR. Las variables consideradas son la tensión del arco, la velocidad de soldeo, la velocidad de alimentación del electrodo y la separación de las superficies a unir. Las funciones de respuesta consideradas son el sobreespesor, anchura, penetración y el ángulo del cordón. Los resultados obtenidos mediante MSR se ajustan muy bien a los valores experimentales. El procedimiento es validado experimentalmente mediante el soldeo, para las condiciones tecnológicas optimizadas obtenidas de forma teórica, existiendo una gran concordancia entre los valores teóricos y los experimentales.

  11. Impacto del Ministerio Juvenil en los jovenes de colombia

    OpenAIRE

    Barrero, Uriel; Corporación Universitaria Adventista de Colombia

    2015-01-01

    Investigación solicitada por la IASDC sobre algunas actividades y programas que han sido de gran beneficio para el aspecto espiritual de los jovenes en el ministerio Juvenil de la union colombiana del norte.

  12. Unions and the Economic Basis of Attitudes

    OpenAIRE

    White, Michael; Bryson, Alex

    2016-01-01

    Unions make differences to employee satisfaction that correspond to their effects on individual economic advantage. Panel data reveal how changes in economic circumstance and changes in job satisfaction are linked to changes in union coverage. When individuals move into a union covered job they receive a wage mark-up and express enhanced pay satisfaction. Conversely, those moving from a union covered job on average lose any mark-up and have significantly reduced satisfaction. Similar findings...

  13. Coste por proceso en el tratamiento quirúrgico del cáncer de piel Cost per episode of care in the surgical treatment of skin cancer

    Directory of Open Access Journals (Sweden)

    Ángela Hernández Martín

    2006-08-01

    Full Text Available Antecedentes: El cáncer cutáneo es la neoplasia maligna más frecuente en humanos. Su tratamiento puede ser efectuado con diversas técnicas y por diferentes especialistas, y la escisión quirúrgica es el método terapéutico con menor tasa de recidivas. Objetivos: Evaluar el coste por proceso del tratamiento quirúrgico del cáncer cutáneo no melanoma (CCNM cuando es realizado por un servicio de dermatología. Material y método: Definición del proceso asistencial como conjunto de actividades clínicas que conducen al tratamiento quirúrgico del CCNM por parte de un especialista en dermatología, y cálculo del coste por proceso empleando los datos económicos facilitados por la institución sanitaria pública en que se ha realizado el análisis. Resultados: El gasto por proceso varió entre 273,71 y 1.129,84 euros, dependiendo del procedimiento quirúrgico y de los recursos sanitarios empleados. Conclusiones: El cáncer cutáneo es una de las enfermedades dermatológicas cuyo aspecto clínico suele ser inequívoco para los dermatólogos, por lo que muchas veces ni siquiera se precisa una confirmación histológica para diagnosticarlo y decidir la pauta terapéutica correspondiente. Este hecho hace que los dermatólogos quirúrgicos sean muy eficientes, ya que el proceso se realiza con un mínimo de episodios asistencia-les y solamente en los pacientes adecuados. El coste del tratamiento varía sustancialmente en función de la complejidad de la intervención y el escenario quirúrgico donde se realiza.Background: Skin cancer is the most common form of malignancy in humans. It can be treated with various techniques and by different specialists. The procedure with the lowest failure rates is surgical excision. Objectives: To calculate the cost per episode of care in the surgical treatment of non-melanoma skin cancer (NMSC when performed by dermatologists. Material and method: An episode of NMSC surgical care was defined as the series of

  14. Cancer incidence in Gipuzkoa, Spain (1998-2002, and time trends from 1986 Incidencia del cáncer en Guipúzcoa (1998-2002 y tendencias desde 1986

    Directory of Open Access Journals (Sweden)

    Nerea Larrañaga

    2008-06-01

    Full Text Available Objectives: To determine the cancer incidence in Gipuzkoa (Spain from 1998 to 2002 and describe time trends since 1986. Methods: The annual incidence of cancer in Gipuzkoa from 1998 to 2002 was estimated as a rate per 100,000 inhabitants. Incidence trends for the period 1986-2002 were studied for all cancers and for the main cancer sites using Poisson regression and Joinpoint regression for prostate tumours. Results: On average, one in 3 men and one in 5 women would probably be diagnosed with cancer at some time during their life (0-74 years. Among men, prostate surpassed lung as the most frequent cancer site. Among women, breast cancer represented approximately 30% of all cases of cancer (excluding non-melanoma skin cancers. There was an annual increase in the incidence of cancer of 1.5% (95% CI, 1.1-1.8 in men and 0.9% (95% CI, 0.5-1.3 in women. The incidence of prostate cancer in men increased over the study period, and especially between 1996 and 1999, with an annual increase of 34.7% (95% CI, 5.9-71.5. The incidence of lung cancer in women presented an annual increase of 5.2% (95% CI, 3.4-7.1. In contrast, the incidence of stomach cancer decreased during the study period. Conclusions: Cancer incidence in Gipuzkoa increased during the study period. This increase was particularly marked in lung cancer and skin melanoma, for which preventive strategies are fundamental.Objetivos: Conocer la incidencia de cáncer en Guipúzcoa entre 1998 y 2002, y su evolución desde 1986. Métodos: Se realizan estimaciones de incidencia anual del cáncer en el período 1998-2002, para Guipúzcoa, en tasas por 100.000 habitantes. Se analiza su evolución entre 1986 y 2002 en el conjunto de localizaciones y en las más frecuentes, mediante el modelo de regresión de Poisson y el modelo de regresión Joinpoint en tumores de próstata. Resultados: Uno de cada 3 varones y una de cada 5 mujeres de Guipúzcoa tienen la probabilidad de desarrollar cáncer a lo largo de

  15. ETUDE - European Trade Union Distance Education.

    Science.gov (United States)

    Creanor, Linda; Walker, Steve

    2000-01-01

    Describes transnational distance learning activities among European trade union educators carried out as part of the European Trade Union Distance Education (ETUDE) project, supported by the European Commission. Highlights include the context of international trade union distance education; tutor training course; tutors' experiences; and…

  16. The African Union and Conflict Management

    Science.gov (United States)

    2006-03-02

    USAWC STRATEGY RESEARCH PROJECT THE AFRICAN UNION AND CONFLICT MANAGEMENT by Lieutenant Colonel Flemming Mathiasen Royal Danish Army Colonel Patrick...AUTHOR: Lieutenant Colonel Flemming Mathiasen TITLE: The African Union and Conflict Management FORMAT: Strategy Research Project DATE: 2 March 2006...WORD COUNT: 5850 PAGES: 28 KEY TERMS: African Union, Africa, Conflict Management , Capabilities CLASSIFICATION: Unclassified Africa is a continent with a

  17. Uniones de nitruro de silicio. Superaleaciones

    Directory of Open Access Journals (Sweden)

    Barea, R.

    2000-10-01

    Full Text Available Industrial applications of silicon nitride materials are limited by the difficulty and cost of making complex shapes. In the present work, the use of some superalloys as bonding interlayer between two silicon nitride pieces has been investigated. Three types of Ni based superalloys have been chosen because their technological interest. Joining experiments have been performed by thermocompression at different temperatures and pressures, in a medium vacuum atmosphere. Reactions taking place at the superalloy / Si3N4 interface have been studied using energy dispersive X-ray spectroscopy and scanning electron microscopy. A comparative study among the three superalloys /Si3N4 interfaces has been done.

    El posible uso del nitruro de silicio en el ámbito industrial se ve limitado por la dificultad y el coste que supone mecanizar geometrías complicadas. En el presente trabajo se estudia la posibilidad del uso de superaleaciones como interlámina de unión entre piezas de este material. Se han seleccionado tres superaleaciones con base niquel-cromo debido a su interés tecnológico. Las uniones se han llevado a cabo por termocompresión en vacío, utilizando varias presiones y temperaturas. Se ha realizado un estudio comparativo de las intercaras de unión en las tres aleaciones, analizando mediante microanálisis por energías dispersadas de Rayos X y microscopía electrónica de barrido las reacciones que tienen lugar.

  18. Improving cervical cancer screening in Mexico: results from the Morelos HPV Study Mejorando la detección oportuna del cáncer cervical en México: resultados del Estudio de VPH en Morelos

    Directory of Open Access Journals (Sweden)

    Yvonne Flores

    2003-01-01

    Full Text Available OBJECTIVE: The purpose of this paper is to describe some of the results of the Morelos HPV Study. The main objective of the Morelos HPV Study is to evaluate the use of human papillomavirus (HPV DNA testing, as compared to the Papanicolaou (Pap test, for cervical cancer (CC screening. MATERIAL AND METHODS: The Morelos HPV Study is currently being conducted in Mexico, to examine the possibility of using HPV testing for CC screening. The HPV testing of self-collected vaginal and clinician-collected cervical specimens was evaluated as part of this study. The acceptability of the HPV testing of self-collected specimens was compared to that of the Pap test. A cost-effectiveness analysis (CEA and cost-benefit analysis (CBA was also performed. RESULTS: The Morelos HPV Study results indicate that HPV testing has a greater sensitivity to detect cervical intraepithelial neoplasia (CIN 2/3 and CC than the Pap test. Our results also indicate an over-all lower acceptability of the Pap test as compared to the self-collected procedure. The results of the CEA and CBA indicate that screening women between the ages of 20-80 for CC using some type of HPV testing is always more cost-effective than screening for CC using the Pap test. CONCLUSIONS: Our results suggest that self- and clinician-collected HPV testing could be used in CC prevention programs, as an effective complement or substitute for the Pap test.OBJETIVO: Describir algunos de los resultados del Estudio de VPH en Morelos. El objetivo principal del Estudio de VPH en Morelos es evaluar el uso de la prueba del virus de papiloma humano (VPH, en relación con la prueba de Papanicolaou, para el tamizaje de cáncer cervical. MATERIAL Y MÉTODOS: El Estudio de VPH en Morelos actualmente se está llevando a cabo en México, para examinar la posibilidad de usar la prueba de VPH para la detección de cáncer cervical. Se evaluó el uso de la prueba de VPH en muestras auto-tomadas vaginales y en muestras cervicales

  19. Variantes del Papilomavirus Humano 16 y su asociación con el HLA en cáncer cervical Variants of Human Papillomavirus 16 and its association with HLA in cervical cancer

    Directory of Open Access Journals (Sweden)

    Jehidys Montiel Ramos

    2010-12-01

    Full Text Available El cáncer cervical es el segundo cáncer más común en mujeres en el mundo y es el principal cáncer en mujeres en países en desarrollo. La infección persistente por los genotipos oncogénicos del Virus del Papiloma Humano (VPH es la causa necesaria para el desarrollo del cáncer cervical, siendo el VPH-16 el genotipo responsable del 50-60% de los casos. Las variantes No Europeas del VPH-16 han sido asociadas con infección persistente, lesiones de alto grado y cáncer. Los polimorfismos del Antígeno Leucocitario Humano (HLA están también asociados con la susceptibilidad al cáncer cervical y se ha postulado una relación entre variantes del VPH y ciertos alelos del HLA. La presente revisión hace referencia a la relación entre los polimorfismos de HLA y el desarrollo de cáncer cervical y la evidencia que documenta la interrelación de este factor con la variabilidad del VPH-16. Salud UIS 2010; 42: 272-280Cervical cancer is the second most common cancer in women worldwide and the most frequent cancer in women of the majority of developing countries. Persistent infection with Human Papillomavirus (HPV oncogenic types of HPV is necessary to develop cervical, cancer, with HPV-16 responsible for 50-60% of cases. Non-European variants of HPV-16 have been associated with persistant infection and high degree cervical cancer. Human Leucocyte Antigen (HLA polymorphisms are also associated with susceptibility to cervical cancer. It has been suggested relationship between HPV-16 variability and some HLA Alleles., This revision refers to the relation between HLA polymorphisms and cervical cancer development, and present evidence that may explain its relation with HPV-16 variability. Salud UIS 2010; 42: 272-280

  20. Nuclear Energy and European Union

    International Nuclear Information System (INIS)

    Picamal, B.

    2010-01-01

    The interest shown by the European Institutions in the energy debates, in which the nuclear energy is included as a key component within the energy mix, is obvious. Climate change and energy supply have pushed some countries to publicly express their interest for developing the nuclear energy. These positions are however in contradiction with some others within the European Union which are a lot more critical towards this type of energy and where face-out policies still prevail. Despite the fact that the use of the nuclear energy will remain within the competence of each Member State, the European Union will continue to play a prominent role in the development of an energy strategy based on a low carbon economy. (Author)

  1. The European Union's Africa Policy

    DEFF Research Database (Denmark)

    Olsen, Gorm Rye

    2013-01-01

    For a number of years, there has been an international debate on whether and to what extent small member states can influence the common external policies of the European Union. Recent research on the role of small EU states concludes that these states are neither per se political dwarfs nor power...... including North–South and specifically Africa policies. Five separate analyses are carried out addressing the question of Nordicization and Europeanization. Based on the empirical analyses, it is not possible to confirm the hypothesis that a Nordicization of the European Union's Africa policy has taken...... place. Rather, it appears adequate to talk about convergence of policies between the Nordics and the EU and therefore, the Africa policies of both actors are basically the result of Europeanization....

  2. Labor Unions and Asset Prices

    DEFF Research Database (Denmark)

    Busato, Francesco; Addessi, William

    The paper investigates the nexus between labor and financial markets, focusing on the interaction between labor union behavior in setting wages, firms' investment strategy and asset prices. The way unions set wage claims after observing firm's financial performance increases the volatility of firms......' returns and the riskiness of corporate ownership. To remunerate this higher volatility and stronger risk, firms' equities have to grant high return. This mechanism is able to offer an explanation of for the "equity puzzle", that is it can explain the difference between equity returns and the risk free...... rate. It is a welcome result that the simulated excess return is about the empirical estimate and this result is obtained with a logarithmic specification of the shareholders preferences....

  3. European Union: fears and hopes

    Directory of Open Access Journals (Sweden)

    Gilles ROUET

    2016-06-01

    Full Text Available This contribution analyses some data from Eurobarometer 83, spring 2015, especially to draw a map of Fears. The European Union is a divided space and one of the main consequences of the budget (financial crisis of Greece, followed by the crisis caused by the arrival of thousands of immigrants is an enhanced communication difficulty between the Western and Eastern parts of the EU But all citizens have some new rights with the European Citizenship, which are additional. One of the main issues for the future could be to change the fundamental basis of the Union, thus trying to organize a new articulation between local and supranational, with another role for States, for example to change the organisation of European elections, and to pursue the connection of public spaces with mobility.

  4. The Baltic States and their «return to Europe» : from the break with the USSR to integration into the European Union and NATO | El «retorno a Europa» de los Países Bálticos : de la ruptura con la URSS a la integración en la Unión Europea y la Alianza Atlántica del siglo XXI

    Directory of Open Access Journals (Sweden)

    Guillermo A. Pérez Sánchez

    2004-12-01

    Full Text Available Between August and September 1991, the Baltic States forced their break with the USSR, just a few months before the latter disintegrated. From that moment on, the recovery of national independence and sovereignty – first established during the inter-war period only to be thwarted by the pact between Germany and the Soviet Union in 1939 – as well as the consolidation of democracy, the rule of law and a market economy, were given impetus by their desire to join the European Union and the North Atlantic Treaty Organization. After more than a decade of major transformations, both political and socio-economic in nature, the three Baltic States – Lithuania, Estonia and Latvia – have successfully achieved the two fundamental prerequisites for a future of peace, liberty, prosperity and security in the twenty-first century: their «return to Europe» as members of the European Union and their link with the Euro-Atlantic military alliance as members of NATO. | Entre agosto y septiembre de 1991, los Países Bálticos forzaron su ruptura con la Unión Soviética, pocos meses antes de que ésta se desintegrara totalmente. A partir de ese momento, la recuperación de su independencia y soberanía nacional -fraguada por primera vez en la época de entreguerras y frustrada por el pacto germano-soviético de 1939-, así como la consolidación de la democracia y el Estado de Derecho y la economía social de mercado, fue de la mano de su aspiración de integración en la Unión Europea y en la Organización del Tratado del Atlántico Norte. Después de más de una década de grandes transformaciones, tanto políticas como socioeconómicas, los tres Países Bálticos -Lituania, Estonia y Letonia- han logrado cumplir con éxito aquellos dos objetivos fundamentales para su futuro en paz, libertad, prosperidad y seguridad en el siglo XXI: el «retorno a Europa» en el marco de la Unión Europea y su vinculazión a la alianza militar euroatlántica dentro de la

  5. Evaluación del seguimiento de mujeres con cáncer cervicouterino en dos policlínicos. Pinar del Río Follow-up assessment of women suffering from cervical uterine cancer in two polyclinics, Pinar del Rio

    Directory of Open Access Journals (Sweden)

    José Guillermo Sanabria Negrín

    2012-06-01

    Full Text Available Introducción: A pesar de contar con un programa de detección precoz del cáncer cervicouterino de larga duración aún no se logran los resultados esperados. Objetivo: Caracterizar a las pacientes con cáncer invasor del cuello uterino en dos áreas de salud de Pinar del Río en el quinquenio 2003-2007. Material y Método: Estudio observacional, transversal, de cohorte, retrospectivo de mujeres de cualquier edad con diagnóstico de cáncer cervicouterino invasor. La información de las pacientes se tomó de los registros automatizados de las lesiones de cuello uterino de la consulta provincial de Patología de Cuello, del Provincial de Cáncer (Dirección Provincial de Salud, y del de Mortalidad General (Dirección Provincial de Salud así como de las historias clínicas de la Unidad Oncológica Provincial. Entre las variables estudiadas estuvieron si procedían o no del programa, edad, estadio clínico, tratamiento recibido, incidencia anual y el promedio en la etapa, la mortalidad y la letalidad. Resultados: Se encontró que el 70,6% de casos no se detectó por programa. La tasa de incidencia promedio fue 29.5 por 100000 mujeres de 15 años y más. Todas las pacientes recibieron el tratamiento oncoespecífico según estadio clínico. Las mayores tasas de mortalidad se encontraron en las pacientes en estadio IIIB al diagnóstico. Conclusiones: Se detectan fallas en la Atención Primaria de Salud, por falta de detección. Las tasas de incidencia de esta enfermedad no se han logrado disminuir. Y se siguen diagnosticando casos en estadios avanzados de la enfermedad, lo que acorta la sobrevida de estas pacientes.Introduction: Despite of having a program, for a long time, to the early detection of cervical uterine cancer, the results expected are not as far achieved. Objective: to characterize the patients suffering from invasive cervical uterine cancer in two health areas in Pinar del Rio province throughout five years (2003-2007. Material and

  6. Ambient air pollution as a risk factor for lung cancer La contaminación del aire como factor de riesgo de cáncer pulmonar

    Directory of Open Access Journals (Sweden)

    AARON J COHEN

    1997-07-01

    Full Text Available Epidemiologic studies over the last 40 years have observed that general ambient air pollution, chiefly due to the by- products of the incomplete combustion of fossil fuels, is associated with small relative increases in lung cancer. The evidence derives from studies of lung cancer trends, studies of occupational groups, comparisons of urban and rural populations, and case-control and cohort studies using diverse exposure metrics. Recent prospective cohort studies observed 30-50% increases in the risk of lung cancer in relation to approximately a doubling of respirable particle exposure. While these data reflect the effects of exposures in past decades, and despite some progress in reducing air pollution, large numbers of people in the US continue to be exposed to pollutant mixtures containing known or suspected carcinogens. These observations suggest that the most widely cited estimates of the proportional contribution of air pollution to lung cancer occurrence in the US, based largely on the results of animal experimentation, may be too low. It is important that better epidemiologic research be conducted to allow improved estimates of lung cancer risk from air pollution in the general population. The development and application of new epidemiologic methods, particularly the improved characterization of population-wide exposure to mixtures of air pollutants and the improved design of ecologic studies, could improve our ability to measure accurately the magnitude of excess cancer related to air pollution.En los estudios epidemiológicos llevados a cabo durante los últimos 40 años se ha observado que la contaminación del aire en general, debida sobre todo a los residuos de la combustión incompleta de combustibles fósiles, se ha asociado a pequeños incrementos relativos de cáncer pulmonar. La evidencia procede de estudios sobre tendencias de cáncer del pulmón, de aquellos sobre grupos ocupacionales, de comparaciones entre poblaciones

  7. union publique HR

    CERN Multimedia

    CERN. Geneva

    2010-01-01

    Chers Collègues,Je me permets de vous rappeler qu'une réunion publique organisée par le Département HR se tiendra aujourd'hui:Vendredi 30 avril 2010 à 9h30 dans l'Amphithéâtre principal (café offert dès 9h00).Durant cette réunion, des informations générales seront données sur:le CERN Admin e-guide, qui est un nouveau guide des procédures administratives du CERN ayant pour but de faciliter la recherche d'informations pratiques et d'offrir un format de lecture convivial;le régime d'Assurance Maladie de l'Organisation (présentation effectuée par Philippe Charpentier, Président du CHIS Board) et;la Caisse de Pensions (présentation effectuée par Théodore Economou, Administrateur de la Caisse de Pensions du CERN).Une transmission simultanée de cette réunion sera assur...

  8. A novel loss-of-function heterozygous BRCA2 c.8946_8947delAG mutation found in a Chinese woman with family history of breast cancer.

    Science.gov (United States)

    Ma, Jing; Yang, Jichun; Jian, Wenjing; Wang, Xianming; Xiao, Deyong; Xia, Wenjun; Xiong, Likuan; Ma, Duan

    2017-04-01

    Breast cancer is the most frequent female malignancy worldwide. Among them, some cases have hereditary susceptibility in two leading genes, BRCA1 and BRCA2. Heterozygous germ line mutations in them are related with increased risk of breast, ovarian and other cancer, following autosomal dominant inheritance mode. For purpose of early finding, early diagnosis and early treatment, mutation detecting of BRCA1/2 genes was performed in unselected 300 breast or ovarian patients and unaffected women using next-generation sequencing and then confirmed by Sanger sequencing. A non-previously reported heterozygous mutation c.8946_8947delAG (p.D2983FfsX34) of BRCA2 gene was identified in an unaffected Chinese woman with family history of breast cancer (her breast cancer mother, also carrying this mutation). The BRCA2-truncated protein resulted from the frame shift mutation was found to lose two putative nuclear localization signals and a Rad51-binding motif in the extreme C-terminal region by bioinformatic prediction. And then in vitro experiments showed that nearly all the mutant protein was unable to translocate to the nucleus to perform DNA repair activity. This novel mutant BRCA2 protein is dysfunction. We classify the mutation into disease causing and conclude that it is the risk factor for breast cancer in this family. So, conducting the same mutation test and providing genetic counseling for this family is practically meaningful and significant. Meanwhile, the identification of this new mutation enriches the Breast Cancer Information Core database, especially in China.

  9. Revitalizing the Malaysian Trade Union Movement

    DEFF Research Database (Denmark)

    Wad, Peter

    2012-01-01

    The article takes an historic perspective on contemporary issues of trade union revival in Malaysia, focusing on the challenge of raising union density and analysing the process of organizing employees in the strategically important electronics industry. It concludes that the political support...... for transnational corporations in the electronics industry is declining. This strategic shift enables union activists to bypass enterprise and state-based unions and to establish larger, regionally based unions. However, newly organized unions have not yet overcome resistance from global corporations, nor have...... organizations prefer non-partisan engagement. In order to revitalize themselves, the unions must demonstrate to the Malaysian public that they are both relevant and important for increased productivity and that they can play a significant role in enabling Malaysia to move beyond the middle-income ‘trap’ towards...

  10. Social Customs and Trade Union Membership

    DEFF Research Database (Denmark)

    Ibsen, Christian Lyhne; Toubøl, Jonas; Jensen, Daniel Sparwath

    2017-01-01

    In this article, we investigate the effect of social customs on one of the most important instances of collective action, namely, workers uniting in trade unions. Although many studies have used social custom theory to explain unionization, existing studies have not adequately analysed social...... customs at the workplace. Using workplace union density as a proxy for social custom, this analysis improves existing studies in a number of ways. First, multi-level analyses of a large panel data set from Denmark reveal that there is a significant positive effect of workplace union density...... in unionization are required to create self-sustaining social customs for union membership. Thirdly, we test the acceleration using segmented regression analysis and find a significant acceleration around 45–65 per cent workplace union density. In the conclusion, we discuss the implications of our study...

  11. Protocolo de diagnóstico y tratamiento del cáncer tiroideo Protocol of diagnosis and treatment of thyroid cancer

    Directory of Open Access Journals (Sweden)

    Ramón González Fernández

    2004-06-01

    Full Text Available En este trabajo se plasma el manejo de los pacientes con de cáncer del tiroides, teniendo en cuenta, el uso de los medios diagnósticos, en particular la importancia del uso de la biopsia aspirativa con aguja fina para el diagnóstico precoz. Se sabe que en las últimas décadas han existido criterios más conservadores en lo referido a la suficiencia en la extensión de la operación, en los cánceres bien diferenciados, motivado esto por el mayor conocimiento de la biología del tumor, el desarrollo de pruebas de inmunohistoquímica, tratamiento adyuvante y un seguimiento más estrecho. Por lo que esto ha motivado ciertos criterios controvertidos. Se expone un protocolo de diagnóstico y tratamiento, teniendo en cuenta un adecuado estadiamiento, y definición de los grupos de riesgo, parámetro importante y novedoso en esta entidadIn this paper, the management of patients with thyroid cancer is dealt with taking into account the use of the diagnostic tools and, in particular, the importance of the use of fine-needle aspiration biopsy for the early diagnosis. In the last decades, there have been more conservative criteria regarding the sufficiency in the extension of surgery in the well differentiated cancers, motivated by the greater knowledge of tumor biology, the development of immunohistochemical tests, adjuvant treatment and a closer follow-up. This has led to the appearance of certain controversial criteria. A protocol of diagnosis and treatmemt is exposed taking into consideration an adequate staging and definition of the risk groups, an important and novel parameter in this entity

  12. Vacunas terapéuticas recombinantes contra el cáncer del cuello uterino Recombinant therapeutic vaccines against invasive cervical cancer

    Directory of Open Access Journals (Sweden)

    JAIME BERUMEN

    1997-07-01

    Full Text Available Durante el desarrollo del cáncer cervicouterino se inducen mecanismos para evadir el sistema inmune, como son la disminución de la expresión de moléculas de antígeno mayor de histocompatibilidad I y la secreción de citocinas por las células tumorales. Como consecuencia de ello, la estimulación de linfocitos T citotóxicos (LTC y cooperadores (TC, de células asesinas naturales (AN y macrófagos es muy deficiente. Para inducir una respuesta inmune efectiva contra el tumor, se requiere la estimulación simultánea de múltiples componentes del sistema inmune: por vía sistémica la estimulación de LTC y TC contra epítopos del virus del papiloma humano, y en un nivel local, la inducción de la secreción de citocinas por el tumor, para aumentar el procesamiento y la presentación de blancos tumorales, así como la estimulación de los linfocitos, AN y macrófagos que infiltran el tumor.Several mechanisms to evade the immune system are induced during cervical cancer development, including the decrease of expression of class I HLA molecules and secretion of specific cytokines by tumoral cells. Consequently, the stimulation of cytotoxic (CTL and helper (TH T lymphocytes, as well as the natural killer (NK cells and macrophages is very poor. The induction of immune response against tumors needs the stimulation of multiple components of the immune system: systemic stimulation of CTL and TH against Human Papilloma Virus epitopes and directly in the tumor the secretion of specific cytokines to increase the antigen processing and presentation of tumoral targets, and the stimulation of lymphocyte, NK cells and macrophages that infiltrate tumors.

  13. Unions and the Sword of Justice: Unions and Pay Systems, Pay Inequality, Pay Discrimination and Low Pay

    OpenAIRE

    A Charlwood; K Hansen; David Metcalf

    2000-01-01

    Dispersion in pay is lower among union members than among non-unionists. This reflects two factors. First, union members and jobs are more homogeneous than their non-union counterparts. Second, union wage policies within and across firms lower pay dispersion. Unions'' minimum wage targets also truncate the lower tail of the union distribution. There are two major consequences of these egalitarian union wage policies. First, the return to human capital is lower in firms which recognise unions ...

  14. Delay of medical care for symptomatic breast cancer: a literature review El retraso en la atención médica del cáncer de mama: una revisión de la literatura

    Directory of Open Access Journals (Sweden)

    Karla Unger-Saldaña

    2009-01-01

    Full Text Available The purpose of this paper is to organize and summarize existing information on delayed medical attention for women with breast cancer and identify research needs in this area. This review is organized in six parts: origins and permanence of the message "do not delay" medical attention for potential cancer symptoms; definition and classification of breast cancer delay; impact of delay on breast cancer prognosis; factors related to breast cancer delay and the ways these have been studied; the study of breast cancer delay in Mexico; and directions for future research in developing countries, with a special focus on Mexico. We point out the need of a more integral study of delay that takes into account socio-structural and health services factors, in order to find modifiable factors towards which political actions should be directed to improve breast cancer medical attention in underdeveloped countries.El objetivo de esta revisión es integrar información disponible con respecto al retraso en la atención médica del cáncer de mama e identificar necesidades de investigación en este tema. La revisión consta de seis apartados: origen del mensaje "no retrasar" ante la aparición de síntomas de cáncer; definición y clasificación del retraso en la atención del cáncer de mama; impacto del retraso sobre el pronóstico de la enfermedad; factores asociados con el retraso; la investigación del retraso en la atención del cáncer de mama en México; y necesidades de investigación en este tema. Se señala la necesidad de estudiar el retraso en la atención del cáncer de mama de forma más integral, tomando en cuenta características socio-estructurales y de servicios de salud, para identificar factores modificables hacia los cuales dirigir esfuerzos para mejorar la atención de esta enfermedad en países en vías de desarrollo.

  15. Five-year economic evaluation of non-melanoma skin cancer surgery at the Costa del Sol Hospital (2006-2010).

    Science.gov (United States)

    Aguilar-Bernier, M; González-Carrascosa, M; Padilla-España, L; Rivas-Ruiz, F; Jiménez-Puente, A; de Troya-Martín, M

    2014-03-01

    The cost associated with treatment of non-melanoma skin cancer is expected to rise considerably over the coming decades. This important public health problem is therefore expected to have an enormous economic impact for the various public health services. To estimate the cost of the surgical-care process of non-melanoma skin cancer at the Costa del Sol Hospital and seek areas to improve its efficiency, using the activity-based costing (ABC) method and the tools designed for decision analysis. To compare the costs for hospitalized patients obtained using the ABC method with the data published by the Spanish Ministry of Health, using the diagnosis-related groups (DRG) classification system. Retrospective analysis of the cost of non-melanoma skin cancer surgery at the Costa del Sol Hospital. The total estimated cost from 2006 to 2010 was 3 398 540€. Most of the episodes (47.3%) corresponded to minor outpatient surgery. The costs of the episodes varied greatly according to the type of admission: 423€ (minor outpatient surgery), 1267€ (major outpatient surgery), and 1832€ (inpatient surgery). The average cost of an inpatient episode varied significantly depending on the calculation system used (ABC: 2328€ vs. DRG: 5674€). The ABC cost analysis system favours standardization of the care process for these tumours and the detection of areas to improve efficiency. This would enable more reliable economic studies than those obtained using traditional methods, such as the DRG. © 2013 The Authors Journal of the European Academy of Dermatology and Venereology © 2013 European Academy of Dermatology and Venereology.

  16. Las relaciones ciencia- tecnología- sociedad en el diagnostico temprano del cáncer del pulmón The science-technology-society relationship point of view in the Lung Cancer early diagnosis

    Directory of Open Access Journals (Sweden)

    Alina Monteagudo Canto

    2004-08-01

    Full Text Available El trabajo constituye un análisis al proyecto “Diagnóstico temprano del cáncer de pulmón. Establecimiento de un algoritmo de trabajo”. El objetivo general es proporcionar un estudio social desde la perspectiva del enfoque Ciencia Tecnología Sociedad y fundamentar el proyecto como un proyecto de innovación tecnológica de tipo organizacional. Se revelan conceptos necesarios, como tecnología en su visión tradicional y moderna y el de innovación tecnológica. Se analiza al cáncer de pulmón como objeto de estudio de la ciencia medica y de acción tecnológica y se valoran las condiciones sociales que en Cuba propician el estudio del cáncer pulmón, y cómo se manifiesta la transferencia de tecnología en esta esfera de la salud. Para ello se concibe el razonamiento a través del contexto social, económico, político y científico; se reconocen los problemas y las soluciones en la investigación. Por último, se identifican los impactos de la innovación tecnológica. Se trata en el presente trabajo de hacer válida la tesis que los estudios CTS en Cuba constituyen un campo de reflexión y acción de carácter crítico e interdisciplinario relacionado con las influencias que cada contexto sociocultural ejerce sobre el desarrollo de la ciencia y la tecnología y los impactos sociales de estosThis work is an analysis of the project “Early diagnosis of lung cancer. Establishment of a work algorithm”. The general objective is to provide a social study from the perspective of the Science Technology Society approach and to support the project as a project of technological innovation of organizational type. Necessary concepts are revealed, as technology in their traditional and modern vision and that of technological innovation. Lung cancer is analyzed as object of study of medical science and of technological activity. The social conditions that propitiate the study of the cancer lung in Cuba are valued, and how technology transfer is

  17. Abordaje multidisciplinar en el tratamiento del cáncer de recto: eficacia del tratamiento neoadyuvante Multidisciplinary approach to the treatment of rectal cancer: the benefits of neoadjuvant therapy

    Directory of Open Access Journals (Sweden)

    P. Priego

    2008-07-01

    Full Text Available Objetivo: evaluar el papel de la terapia neoadyuvante en el tratamiento del cáncer de recto en nuestro hospital, tras la implantación de un grupo multidisciplinar de trabajo (MDT. Material y métodos: desde enero de 2000 hasta diciembre de 2005 se ha evaluado en sesión clínica por el grupo MDT un total de 90 pacientes diagnosticados de adenocarcinoma de recto e intervenidos quirúrgicamente tras recibir tratamiento neoadyuvante con radioquimioterapia (QMRT. La edad media fue de 65,04 años (21-83 años, siendo un 67% varones y un 33% mujeres. Los procedimientos quirúrgicos realizados fueron fundamentalmente resección anterior baja en un 50% y amputación abdominoperineal en un 42,2%. Resultados: la tasa de complicaciones asociada al uso del tratamiento neoadyuvante fue del 54,44%, siendo más frecuentes las gastrointestinales. Sin embargo, esta toxicidad fue bien tolerada en la mayor parte de los casos, siendo grave y acarreando la suspensión del tratamiento quimioterápico en 2 pacientes (2,2%. El análisis anatomopatológico de las piezas resecadas demostró una respuesta completa en 10 casos (11,1% y una respuesta parcial (disminución del parámetro T de la clasificación TNM en 32 casos (35,6%, con lo que la respuesta global del tratamiento neoadyuvante fue del 46,6%. Entre las complicaciones postoperatorias se produjeron un 8,3% de dehiscencias anastomóticas, un 34,2% de complicaciones de la herida perineal y un 12,2% de complicaciones urinarias. La mortalidad quirúrgica fue del 0%. La tasa de recidiva pélvica fue del 4,4% y la sistémica del 22,2%. La supervivencia actuarial global y libre de enfermedad a los 5 años fue del 80 y 64% respectivamente. Conclusión: el tratamiento QMRT neoadyuvante proporciona una cifras bajas de recidiva pélvica junto con buenas tasas de supervivencia, no añadiendo una morbimortalidad importante al acto quirúrgico. La evaluación sistemática por un grupo MDT en el contexto de un protocolo cl

  18. Women, Working Families, and Unions

    OpenAIRE

    Janelle Jones; John Schmitt; Nicole Woo

    2014-01-01

    One of every nine women in the United States (11.8 percent in 2013) is represented by a union at her place of work. The annual number of hours of paid work performed by women has increased dramatically over the last four decades. In 1979, the typical woman was on the job 925 hours per year; by 2012, the typical woman did 1,664 hours of paid work per year. Meanwhile, women's share of unpaid care work and housework has remained high. Various time-use studies conclude that women continue to do a...

  19. Trade unions and energy policy

    International Nuclear Information System (INIS)

    Evans, M.

    1984-01-01

    The subject is discussed under the headings: introduction (the review of energy policy by the Trades Union Congress); energy objectives and the energy crisis; energy planning (a planning framework for supply and demand; energy demand management; public planning inquiries; a plan for Britain; beyond Britain); a low energy growth strategy (UK primary energy demand); choice of supplies (coal; oil and gas; nuclear energy); new sources of energy (e.g.solar, geothermal, biofuels, wave, wind, tidal); conservation; health and safety - employers in the energy industries; conclusions. (U.K.)

  20. Soviet Union's Nuclear Power Program

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    Glasnost has dramatically increased the availability of information about the Soviet Union's nuclear industry. In the future, even more information is likely to become known as Soviet participation in international forums increases. Not only is much more general information now available, but up-to-date details are regularly provided, including information such as the Soviet nuclear industry's strategic direction and goals, recent reactor design changes, safety inspection results, and reports of public opposition and protest. This article summarizes the current status of the Soviet nuclear power program, reconciling the often conflicting reports from various public sources

  1. Tendencias del cáncer de mama en América Latina y el Caribe Breast cancer trends in Latin America and the Caribbean

    Directory of Open Access Journals (Sweden)

    Rafael Lozano-Ascencio

    2009-01-01

    Full Text Available OBJETIVO: Describir la magnitud y distribución espaciotemporal del cáncer de mama (CaMa en América Latina y el Caribe (LAC de 1979 a 2005. El CaMa destaca como la causa de muerte más importante por tumores malignos en las mujeres latinoamericanas, incluso por arriba del cáncer cervicouterino. MATERIAL Y MÉTODOS: Revisión y organización de las estadísticas nacionales e internacionales (registros, estudios publicados y bases de datos sobre incidencia y mortalidad. Elaboración de estimadores básicos, razones de mortalidad para cada país y análisis de tendencias. RESULTADOS: Aun con el rezago de información presente en la región, se observa un incremento de la incidencia y la mortalidad por CaMa. La razón de muertes/casos en los países de LAC muestra problemas de acceso a la detección y tratamiento. CONCLUSIONES: El reto es mejorar los sistemas de información y la infraestructura diagnóstica para la detección oportuna y el tratamiento adecuado con la finalidad de detener la tendencia ascendente de la mortalidad prematura.Breast cancer is currently the most significant cause of death from malignancies in Latin American women, including cervical cancer. OBJECTIVE: Describe the magnitude and spatial-temporal distribution of breast cancer in Latin America and the Caribbean (LAC from 1979-2005. MATERIAL AND METHODS: National and international incidence and mortality statistics were reviewed and organized (registries, databases, and published literature, basic estimators and mortality ratios for each country were calculated and trends were analyzed. RESULTS: Despite substantial data gaps in incidence for many countries, an increase in incidence and mortality is observed in LAC countries. Deaths/cases ratios illustrate problems in access to detection and treatment and the greatest gaps are observed in poorer countries. CONCLUSIONS: A regional effort is needed to improve information systems related to cancer in general and breast cancer

  2. Acerca del cáncer cervicouterino como un importante problema de salud pública About uterocervical cancer as an important public health problem

    Directory of Open Access Journals (Sweden)

    Julio César Espín Falcón

    2012-12-01

    Full Text Available El cáncer se presenta como un importante problema de salud, dada la alta morbilidad y mortalidad que produce. Es uno de los procesos más complejos de la naturaleza y resulta el más complicado en la esfera de la medicina por su origen multicausal, la complejidad de sus mecanismos patogénicos y la variedad de formas y tipos que pueden originarse en el ser vivo. El objetivo de este trabajo es ofrecer información útil y actualizada acerca del cáncer cervicouterino. Esta enfermedad es prevenible y curable y se relaciona con la aparición del cáncer en vagina, cuello uterino, vulva y ano; en las mujeres se ha demostrado que la infección por el virus del papiloma humano es un factor de riesgo para su desarrollo. En la actualidad existen y se comercializan en el mundo dos tipos de vacuna, lo que se considera uno de los mayores avances en la medicina preventiva moderna. La aplicación de estas vacunas profilácticas contra el virus del papiloma humano podría reducir la incidencia y mortalidad por cáncer cervicouterino. Esta enfermedad constituye una de las entidades con más impacto y repercusión sobre la salud femenina, particularmente en las mujeres jóvenes. Está considerada una enfermedad emergente desde hace escasos años y sus consecuencias sociales, humanas y económicas lo convierten en un problema importante de salud pública y de la humanidad.Cancer represents an important health problem due to its high morbidity and mortality. It is one of the most complex processes of nature and the most complicated in medicine because of its multiple cause origin, the complexity of its pathogenic mechanisms and the variety of forms and types that may adopt in the subject alive. The objective of this paper was to provide useful and updated information on the uterocervical cancer. This disease is preventable and curable; it is related to the occurrence of cancer in the vagina, the uterine neck, the vulva and the anus. It has been proved that human

  3. La etimología del cáncer y su curioso curso histórico Cancer etymology and its historical curious course

    Directory of Open Access Journals (Sweden)

    Oswaldo Salaverry

    2013-03-01

    Full Text Available Se discuten las primeras descripciones de cáncer en la historia de acuerdo a recientes hallazgos y sus interpretaciones que lo muestra como un grupo de enfermedades raras hasta el siglo XVIII, cuando comenzó su incremento hasta los niveles actuales. La literatura médica muestra numerosos antecedentes de supuestas lesiones cancerosas que, en realidad, corresponden a otras lesiones. Parte de la explicación se refiere a un malentendido etimológico acerca de la palabra griega karkinos que significaba cáncer, en su sentido moderno, pero también lesión ulcerosa. Se revisa ampliamente esta confusión en la antigua literatura médica y luego se esbozan los principales hitos de la concepción moderna del cáncer hasta el siglo dieciochoThe first cancer descriptions in history are discussed according to recent findings and their interpretation, which show it as a group of unknown diseases until the 18th century, when it started to increase to actual levels. Medical literature shows a variety of what were considered cancer lesions, which are actually different lesions. This is partly due to an etymological misunderstanding of the Greek term karkinos that, in its modern sense, meant “cancer”, but also ulcerative lesion. This confusion is widely reviewed in the ancient medical literature and the main landmarks of modern cancer conception up to the 18th century are outlined

  4. Job satisfaction and employee’s unionization decision: the mediating effect of perceived union instrumentality

    Energy Technology Data Exchange (ETDEWEB)

    Shan, H.; Hu, E.; Zhi, L.; Zhang, L.; Zhang, M.

    2016-07-01

    Purpose: Given the current lack of literature in the background of China labor force, this study aims to investigate the relationships among job satisfaction, perceived union instrumentality, and unionization from a reference-frame-based perspective and explore the referred relationships in the context of Chinese labor market. Design/methodology/approach: The study introduces perceived union instrumentality as a mediator to the relationship between job satisfaction and unionization. The applicability of western theories was tested in the Chinese context by a questionnaire survey on 390 employees who were working in private sectors of Jiangsu Province in China. Four hypothesis were proposed and tested by data analysis to verify the model. Findings: The study found that most aspects of job satisfaction were negatively correlated with unionization and perceived union instrumentality, while perceived union instrumentality had a positive relationship with unionization. Perceived union instrumentality was also found to have a mediating effect on the relationship between job satisfaction and unionization. Originality/value: The paper adapted and tested a number of western industrial relation theories in the backdrop of China, contributing to the gap in Chinese-context research by examining the relationships between job satisfaction, unionization and union instrumentality of Chinese employees. It pays a regular contribution to labor union studies both inside and outside China. (Author)

  5. Diagnose of the prostate cancer: Utility of the antigen specifies of prostate, transrectal echography and aspired by fine needle; Diagnostico del cancer de prostata: utilidad del antigeno especifico de prostata, ecografia transrectal y aspirado por aguja fina

    Energy Technology Data Exchange (ETDEWEB)

    De Nubbila, Eduardo; Rosillo, Marco; Fals, Orlando

    1993-04-01

    We describe three improved methods of detecting prostate cancer while it is still confined to the gland: Prostrate specific antigen (PSA), trans-rectal ultrasound (TRUS) and trans-rectal ultrasound-directed prostatic fine needle aspirate (TRFNA). Of a total of 60 studied cases, 23 cytological procedures were done, and half of these were found to have prostate cancer. We compare traditional methods like digital rectal examination and prostatic phosphatase acid with PSA and TRFNA. We conclude that these methods increase the sensibility and specificity of early prostate cancer detection.

  6. The European Union: Challenges and Perspectives

    Directory of Open Access Journals (Sweden)

    Botescu Ion

    2017-01-01

    If to all these we add the protectionist measures that the new president of the United States wishes to implement, as well as some deterioration in the European Union credibility generated by Brexit, the bureaucratic aspects that characterize the European institutions, etc., we can outline the context of the European Union, which requires a series of measures to ensure the progress of the European Union as a whole and, in particular, the effective integration of each Community country.

  7. Trade union policy and nuclear power

    International Nuclear Information System (INIS)

    Elliot, D.

    1981-01-01

    The subject is discussed under the headings: introduction; energy policy; the beginning of doubt; SERA's role [SERA = Socialist Environment and Resources Association]; the 1980 nuclear debate [within the trade union movement]; the 1981 nuclear debate [within the trade union movement]; the issues reviewed (supply and demand; safety and employment; security); review of policy trends; conclusions. Appendix: a review of union policy statements. (U.K.)

  8. Currency Unions, Trade Flows, and Capital Flows

    OpenAIRE

    James Yetman

    2003-01-01

    Trade within currency unions has been shown to be much larger than outside of currency unions, even after factoring in many relevant variables. The existing empirical evidence is based on reduced form models of trade, and therefore indicates that there exists a high correlation between currency union membership and trade, but does not indicate the causality, or the mechanism at work. This paper argues that the balance of evidence points to a large and statistically significant causal relation...

  9. Wage Setting in Democratic Labour Unions

    DEFF Research Database (Denmark)

    Filges, Trine

    1999-01-01

    In this paper, we analyse the wage setting of a democratic labour union. The union members differ with respect to their employment probabilities. The union wage only changes if the parameters of the median member change. An exogenous shock to revenue may increase the wage, even if labour demand...... is iso-elastic and unemployment benefits may have only a small effect on wages if the median member differs from the average. These findings are in accordance with empirical results....

  10. Adolescent Violent Victimization and Precocious Union Formation*

    Science.gov (United States)

    C. Kuhl, Danielle; Warner, David F.; Wilczak, Andrew

    2013-01-01

    This article bridges scholarship in criminology and family sociology by extending arguments about “precocious exits” from adolescence to consider early union formation as a salient outcome of violent victimization for youths. Research indicates that early union formation is associated with several negative outcomes; yet the absence of attention to union formation as a consequence of violent victimization is noteworthy. We address this gap by drawing on life course theory and data from the National Longitudinal Study of Adolescent Health (Add Health) to examine the effect of violent victimization (“street” violence) on the timing of first co-residential union formation—differentiating between marriage and cohabitation—in young adulthood. Estimates from Cox proportional hazard models show that adolescent victims of street violence experience higher rates of first union formation, especially marriage, early in the transition to adulthood; however, this effect declines with age, as such unions become more normative. Importantly, the effect of violent victimization on first union timing is robust to controls for nonviolent delinquency, substance abuse, and violent perpetration. We conclude by discussing directions for future research on the association between violent victimization and coresidential unions with an eye toward the implications of such early union formation for desistance. PMID:24431471

  11. Adolescent Violent Victimization and Precocious Union Formation.

    Science.gov (United States)

    C Kuhl, Danielle; Warner, David F; Wilczak, Andrew

    2012-11-01

    This article bridges scholarship in criminology and family sociology by extending arguments about "precocious exits" from adolescence to consider early union formation as a salient outcome of violent victimization for youths. Research indicates that early union formation is associated with several negative outcomes; yet the absence of attention to union formation as a consequence of violent victimization is noteworthy. We address this gap by drawing on life course theory and data from the National Longitudinal Study of Adolescent Health (Add Health) to examine the effect of violent victimization ("street" violence) on the timing of first co-residential union formation-differentiating between marriage and cohabitation-in young adulthood. Estimates from Cox proportional hazard models show that adolescent victims of street violence experience higher rates of first union formation, especially marriage, early in the transition to adulthood; however, this effect declines with age, as such unions become more normative. Importantly, the effect of violent victimization on first union timing is robust to controls for nonviolent delinquency, substance abuse, and violent perpetration. We conclude by discussing directions for future research on the association between violent victimization and coresidential unions with an eye toward the implications of such early union formation for desistance.

  12. Unionism Comes to the Public Sector

    OpenAIRE

    Richard B. Freeman

    1984-01-01

    This paper argues that public sector labor relations is best understood in a framework that focuses on unions' ability to shift demand curves rather than to raise wages, as is the case in the private sector. It reviews the public sector labor relations literature and finds that: (i) public sector unionism has flourished as a result of changes in laws; (2) the effects of public sector unions on wages are likely to have been underestimated; (3) public sector unions have a somewhat different eff...

  13. Frequency of cancer in children residing in Mexico City and treated in the hospitals of the Instituto Mexicano del Seguro Social (1996–2001)

    International Nuclear Information System (INIS)

    Juárez-Ocaña, Servando; González-Miranda, Guadalupe; Mejía-Aranguré, Juan Manuel; Rendón-Macías, Mario Enrique; Martínez-García, María del Carmen; Fajardo-Gutiérrez, Arturo

    2004-01-01

    The objective of this article is to present the frequency of cancer in Mexican children who were treated in the hospitals of the Instituto Mexicano del Seguro Social in Mexico City (IMSS-MC) in the period 1996–2001. The Registry of Cancer in Children, started in 1996 in the IMSS-MC, is an on-going, prospective register. The data from 1996 through 2001 were analyzed and the different types of cancer were grouped according to the International Classification for Cancer in Children (ICCC). From this analysis, the general and specific frequencies by age and by sex were obtained for the different groups of neoplasms. Also, the frequency of the stage of the disease that had been diagnosed in cases of children with solid tumors was obtained. A total of 1,702 new cases of children with cancer were registered, with the male/female ratio at 1.1/1. Leukemias had the highest frequency with 784 cases (46.1%) and, of these, acute lymphoblastic leukemias were the most prevalent with 614 cases (78.3%). Thereafter, in descending order of frequency, were tumors of the central nervous system (CNST) with 197 cases (11.6%), lymphomas with 194 cases (11.4%), germinal cell tumors with 110 cases (6.5%), and bone tumors with 97 cases (5.7%). The highest frequency of cancer was found in the group of one to four year-olds that had 627 cases (36.8%). In all the age groups, leukemias were the most frequent. In the present work, the frequency of Hodgkin's disease (~4%) was found to be lower than that (~10%) in previous studies and the frequency of tumors of the sympathetic nervous system was low (2.3%). Of those cases of solid tumors for which the stage of the disease had been determined, 66.9% were diagnosed as being Stage III or IV. The principal cancers in the children treated in the IMSS-MC were leukemias, CNST, and lymphomas, consistent with those reported by developed countries. A 2.5-fold reduction in the frequency of Hodgkin's disease was found. Of the children, the stage of

  14. La prevención del cáncer de piel (Preventing Skin Cancer)

    Centers for Disease Control (CDC) Podcasts

    2016-05-31

    Un hombre y una mujer hablan sobre cómo aprendieron a protegerse la piel del sol con los años.  Created: 5/31/2016 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 5/31/2016.

  15. HIFU e nanobolle di ossigeno: due differenti approcci per il trattamento del cancro - HIFU and oxygen load nanobubbles:two different approches for cancer treatment

    Directory of Open Access Journals (Sweden)

    Chiara Magnetto

    2015-07-01

    Full Text Available L’utilizzo di ultrasuoni focalizzati ad alta intensità (HIFU ha ottenuto un rapido consenso in ambito clinico come strumento chirurgico non invasivo per l’ablazione di cellule tumorali. L’impiego di tale tecnologia, applicata simultaneamente a nano-bolle riempite di ossigeno (OLN, realizzate e caratterizzate presso l’INRiM e volte a trattare patologie associate all’ipossia (come i tumori, costituiscono un innovativo strumento terapeutico per la cura del cancro proposto in questo lavoro. ---------- Use of high intensity focused ultrasound (HIFU beam has gained rapid agreement in clinical environment as a tool for non-invasive surgical ablation of tumor cells. This technology, applied simultaneously to nano-bubbles filled with oxygen (OLN, realized and characterized at INRiM with the purpose of treating diseases associated to hypoxia (such as tumors, constitute an innovative therapeutic tool for cancer treatment proposed in this article.

  16. Brazilian union actions for workers' health protection

    Directory of Open Access Journals (Sweden)

    Rodolpho Repullo Junior

    Full Text Available CONTEXT: Many authors have emphasized the importance of worker strength through unionized organizations, in relation to the improvement of working procedures, and have reported on the decisiveness of labor movement actions in achieving modifications within the field of work and health. OBJECTIVE: To describe the ways in which Brazilian unions have tried to intervene in health-illness and work processes, identifying the existence of commonality in union actions in this field. TYPE OF STUDY: Qualitative study. SETTING: Postgraduate Program, Environmental Health Department, Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil. METHODS: Union health advisers and directors were interviewed. Documents relating to union action towards protecting workers' health were collected and analyzed. RESULTS: Unions articulate actions regarding workers' health of a technical and political nature that involve many aspects and high complexity. These have been divided into thematic categories for better analysis. DISCUSSION: Union actions regarding workers' health in Brazil are restricted to some unions, located mainly in the southern, southeastern and northeastern regions of the country. Nonetheless, the unions undertaking such actions represent many professions of great economic and political importance. CONCLUSIONS: The recent changes in health and safety at work regulations, recognition of professional diseases, creation of workers' health services and programs within the unified health system, and operational improvements in companies' specialized safety and occupational medicine services, all basically result from union action. There is commonality of union action in this field in its seeking of technical and political strengthening for all workers and their general and local representation. This has the objective of benefiting collective bargaining between employers and workers. Inter-institutional action on behalf of workers' rights

  17. Denmark and the European Union

    DEFF Research Database (Denmark)

    Manners, Ian

    2011-01-01

    Over the past two decades Morten Kelstrup’s work has been at the centre of three important intellectual innovations in political science – the study of the EU as a regional political system; European security studies; and small states in European integration. Kelstrup’s best known books (Buzan, K...... of this book, two of Kelstrup’s most important intellectual contributions come from his work on Denmark’s relations with the European Union, and his use of systems theory to understand the EU.......Over the past two decades Morten Kelstrup’s work has been at the centre of three important intellectual innovations in political science – the study of the EU as a regional political system; European security studies; and small states in European integration. Kelstrup’s best known books (Buzan...

  18. IDENTITY AND THE EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    Abrudan Cristina

    2008-05-01

    Full Text Available The purpose of this article is to throw some light on the question of identity in the European Union. The challenge is to understand how identity formation takes place in the contemporary world. The European integration has to be understood both as a process of socio-economic convergence among European states but also as a process of co-operation on different other levels, too. It seems that cultures, traditions and interests are more and more interconnected as societies become increasingly multicultural. This is the reason why people are concerned with the concept of identity and the recognition of their uniqueness in terms of traditions, values and ways of lives.

  19. INNOVATION IN THE EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    VLADIMIR-CODRIN IONESCU

    2014-11-01

    Full Text Available In the contemporary knowledge-based society, innovation, as a vector used for the application and promotion of inventions and innovations, is one of the main sources used for obtaining a sustainable competitive advantage. The present paper points out the main directions which the European Commission aims to develop in the sphere of innovation, within the context of the Initiative: “A Union of Innovation”, which is part of the Europe 2020 Strategy. The paper analyses the performances accomplished by the EU states in the area of innovation while developing an international perspective that may represent the starting point in identifying solutions whereby the EU could reduce the gaps that exist in relation to the main international competitors, i.e. South Korea, USA and Japan.

  20. INNOVATION IN THE EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    Vladimir-Codrin IONESCU

    2014-05-01

    Full Text Available In the contemporary knowledge-based society, innovation, as a vector used for the application and promotion of inventions and innovations, is one of the main sources used for obtaining a sustainable competitive advantage. The present paper points out the main directions which the European Commission aims to develop in the sphere of innovation, within the context of the Initiative: “A Union of Innovation”, which is part of the Europe 2020 Strategy. The paper analyses the performances accomplished by the EU states in the area of innovation while developing an international perspective that may represent the starting point in identifying solutions whereby the EU could reduce the gaps that exist in relation to the main international competitors, i.e. South Korea, USA and Japan.

  1. International Union of Radioecologists' activities

    International Nuclear Information System (INIS)

    Auerbach, S.I.

    1983-01-01

    The International Union of Radioecologists (I.U.R.) has maintained a vigorous program of activities in accordance with the goals of its charter. To meet these goals, the I.U.R. has sponsored a number of workshops, meetings, and other related activities aimed at improving our ability to understand and predict the consequences of release of radionuclides to the environment. These include: intercomparison and harmonization of methodologies and a continuous feedback between scientists engaged in mathematical modeling and those carrying out field studies. Specialized workshops dealing with problems in understanding transfer coefficients in the terrestrial environment are being held. In the marine environment, long-distance transport in sediments plays an important role for the spread of radioisotopes released from reprocessing plants (e.g., in the Eastern Atlantic, the Northland Baltic Sea). Representatives of the countries concerned (including from Northern Countries) will define conditions of information exchange, sampling (time, character of sediments), and modelisation

  2. Teacher Union Legitimacy: Shifting the Moral Center for Member Engagement

    Science.gov (United States)

    Popiel, Kara

    2013-01-01

    This mixed-method case study explored teacher union members' beliefs about the teacher union and their reasons for being active or inactive in the union. Findings suggest that teacher unions have gained pragmatic and cognitive legitimacy (Chaison and Bigelow in Unions and legitimacy. Cornell University Press, Ithaca, NY, 2002), but that…

  3. New Roles for the Trade Unions

    DEFF Research Database (Denmark)

    Hull Kristensen, Peer; Sø Rocha, Robson

    2012-01-01

    This article builds on lessons from Denmark and the Nordic area to offer a novel and comprehensive logic of action within the emerging political economy that may be used to assess the possible new roles that unions can take on. The authors argue that unions are capable of “civilizing” globalizati...

  4. Bovine cysticercosis in the European Union

    DEFF Research Database (Denmark)

    Blagojevic, Bojan; Robertson, Lucy J.; Vieira-Pinto, Madalena

    2017-01-01

    -only inspection of slaughtered cattle in order to reduce the potential for cross-contamination with bacteria that are of greatest public health risk, is expected in the European Union in the near future. With this system, the detection sensitivity for bovine cysticercosis that is already low with the current meat...... of bovine cysticercosis in the European Union....

  5. Environment in the European Union 1995

    DEFF Research Database (Denmark)

    The update to the 1992 report on the state of the environment in the European Union requested by the European Commission......The update to the 1992 report on the state of the environment in the European Union requested by the European Commission...

  6. Union innovation in Ontario's nuclear industry

    International Nuclear Information System (INIS)

    MacKinnon, D.

    2003-01-01

    Over the last decade the Power Worker's Union (PWU) has embarked on a number of innovative approaches that have provided significant benefit to the nuclear industry. These include advanced labour relations approaches, equity participation and groundbreaking skills training initiatives. This presentation outlines these and other initiatives in the context of the union's view of the nuclear generation industry's future. (author)

  7. LIMITING ORGANISATIONAL RIGHTS OF MINORITY UNIONS ...

    African Journals Online (AJOL)

    Administrator

    1996-02-19

    Feb 19, 1996 ... market in recent times can be attributed, in part, to inter-union rivalry.1 Minority unions ... March 2013 – resulting in a negative impact on South Africa's GDP and currency depreciation. In. 2013, the .... Organisational rights are regulated by Part A and B of Chapter 111 of the LRA, and the right to strike is ...

  8. Banking Union- Present Stage and its Perspectives

    Directory of Open Access Journals (Sweden)

    Petre Prisecaru

    2014-05-01

    Full Text Available Banking Union is very important for financial stability of EU, for preventing any future crisis, for improving corporate governance in the banking sector, for completing the single market for financial services and for the strengthening of monetary union, for opening the way to fiscal union and to political union. There is not enough theoretical research in the field of banking union, but there are many recent contributions on behalf of foreign and Romanian experts and analysts, which refer mainly to the three components/pillars of EU banking union: a Single Supervision Mechanism (SSM, a Single Resolution Mechanism (SRM and an harmonized system of deposit guarantee schemes. Some micro studies and surveys carried out by prestigious institutions, like Deutsche Bank, Brookings Institution, CEPS have been run over and analyzed together with the positions and opinions of different European officials, and also with the content of EU secondary legislation. An empirical research was made with the aim to identify all essential aspects relating to EU banking union, which may concern the academics, researchers and business community. The paper is based on a previous research study coordinated by author and contains his own conclusions focused on the main arguments in favour of banking union.

  9. Should the 'Outs' Join the Banking Union?

    NARCIS (Netherlands)

    P. Hüttl (Pia); D. Schoenmaker (Dirk)

    2016-01-01

    textabstractThe Single Market stimulates cross-border banking throughout the European Union. This paper documents the banking linkages between the 9 ‘outs’ and 19 ‘ins’ of the Banking Union. We find that some of the major banks, based in Sweden and Denmark, have substantial banking claims across the

  10. 76 FR 79531 - Corporate Credit Unions

    Science.gov (United States)

    2011-12-22

    ... exclude CLF stock subscriptions, based on the asset's negligible credit risk and to facilitate corporate... removing paragraphs (c)(3) and (f)(4) and adding paragraph (h) to read as follows: Sec. 704.6 Credit risk... NATIONAL CREDIT UNION ADMINISTRATION 12 CFR Part 704 RIN 3133-AD95 Corporate Credit Unions AGENCY...

  11. The Defense of Teachers' Trade Union Rights.

    Science.gov (United States)

    Pepin, Luce

    1990-01-01

    The author sees cause for concern in the number of complaints to the International Labour Organisation alleging violations of teachers' union rights. She examines the right of public employees to organize and strike and government interference, concluding that greater protection for teachers' unions may be needed. (SK)

  12. Immigration and the transformation of American unionism

    NARCIS (Netherlands)

    Burgoon, B.; Fine, J.; Jacoby, W.; Tichenor, D.

    2010-01-01

    Does immigration hamper union organizing in the United States? The prevailing literature strongly suggests that it does and for two reasons: first, immigrants increase the labor pool and diminish union influence over the labor market. And second, immigrants may be harder to organize than native

  13. Comportamiento del tamizaje para cancer de cervix en la ciudad de Santa Marta en el año 2005

    Directory of Open Access Journals (Sweden)

    José Abraham Jaramillo Osorio

    2013-10-01

    Full Text Available ResumenObjetivo: analizar los resultados del programa de detección y control de cáncer de cuello uterino en la ciudad de santa marta, Colombia durante el año 2005. Materiales y métodos: la información se obtuvo compilando los registros mensuales del laboratorio de citología de la E.S.E Alejandro Prospero Reverend en Santa Sarta durante el año 2005. Los datos fueron registrados en un archivo excel y luego evaluados mediante el programa Epi-info 2002. Resultados: durante el 2005 se realizaron en los distintos centros y puestos de salud 16683 citologías, 552 fueron inadecuadas (3,3% 534 alteradas (3,2% 340 infección por virus del papiloma humano (V.P.H. (2% 111 casos de lesión intraepitelial de bajo grado (lieb(0,67% 63 casos de lesión intraepitelial de alto grado(0,38% 15 casos de cáncer invasor de cuello uterino(89.9x100.000. En la vereda de machete y el corregimiento de Guachaca el promedio de infección por V.P.H. fue el doble comparado con los restantes. Conclusiones: este análisis permite identificar debilidades en cuanto a la cobertura y el suministro de información del programa de detección y control de cáncer de cuello uterino, además aporta datos de gran utilidad para diseñar estrategias en salud pública tendientes a corregir indicadores epidemiológicos. (Duazary 2006; 1: 32- 37

  14. The two union catalogues of Myanmar

    Energy Technology Data Exchange (ETDEWEB)

    Hla, Win [Myanmar Scientific and Technological Research Dept., Yangon (Myanmar)

    1995-04-01

    The article mentions about the two union catalogues of Myanmar. The first one is the ``Consolidated Catalogue of journals and the periodicals contained in the libraries of Kasuali, Calcutta, Bombay, Madras, Coonoor, Rangoon and Shillong``. This was published by Indian Research Fund Association of Calcutta in 1933. This is the first union catalogue of medical periodicals for both Myanmar and India as well. The second one is ``the Regional Union Catalogue of Scientific Serials: Yangon``. This was published in 1977, its second printing in 1989. This union catalogue excludes medical serials. Twenty libraries took part in the compilation and publishing of the union catalogue with Technical Information Centre of Myanmar Scientific and Technological Research Department, (formerly Central Research Organization), No. 6, Kaba Aye Pagoda Road, Yankin P.O. Yangon, Myanmar, taking the leading role.

  15. Greece and the Missing Banking Union

    DEFF Research Database (Denmark)

    N. Gordon, Jeffery; Ringe, Georg

    2015-01-01

    The Greek Crisis is a crisis rather than a problem due to the vulnerability of Greek banks. While the banks have deep problems, this column argues that these would have been mitigated if a fully operational banking union were in place. A full banking union requires joint banking supervision, join...... bank resolution, and joint deposit insurance. The EZ only has the first so far. Completing the banking union must be part of any long-term solution.......The Greek Crisis is a crisis rather than a problem due to the vulnerability of Greek banks. While the banks have deep problems, this column argues that these would have been mitigated if a fully operational banking union were in place. A full banking union requires joint banking supervision, joint...

  16. The two union catalogues of Myanmar

    International Nuclear Information System (INIS)

    Hla, Win

    1995-01-01

    The article mentions about the two union catalogues of Myanmar. The first one is the ''Consolidated Catalogue of journals and the periodicals contained in the libraries of Kasuali, Calcutta, Bombay, Madras, Coonoor, Rangoon and Shillong''. This was published by Indian Research Fund Association of Calcutta in 1933. This is the first union catalogue of medical periodicals for both Myanmar and India as well. The second one is ''the Regional Union Catalogue of Scientific Serials: Yangon''. This was published in 1977, its second printing in 1989. This union catalogue excludes medical serials. Twenty libraries took part in the compilation and publishing of the union catalogue with Technical Information Centre of Myanmar Scientific and Technological Research Department, (formerly Central Research Organization), No. 6, Kaba Aye Pagoda Road, Yankin P.O. Yangon, Myanmar, taking the leading role

  17. The european union as subjects of law

    Directory of Open Access Journals (Sweden)

    Fila R.

    2012-10-01

    Full Text Available At the international level it is recognized that development and progress of the new and unique international organization – European Union – is one of the appropriate form of the international organization’s integration. Although European Union was establish as international economic organization, it has gradually integrated the various “best practices” ideas from different governmental systems. Encouragement and motives for cooperation of Member states indicate that member states give more competences of government to the international organization’s institutes. Wherewith, it is observed that the economic and political internationalization has led to disappearance of integrity of territory of member states. The above mentioned opinion is not based on research of the European Union as international organization from standpoint of international law, but from standpoint of theory law – could give juridical estimate regarding executive power in European Union and who could define particular source and entity of administrative law of European Union.

  18. CFC legislation in the European Union

    Directory of Open Access Journals (Sweden)

    Cvjetković Cvjetana M.

    2015-01-01

    Full Text Available In this paper the author considers CFC legislation in the Member States of the European Union, and points to the official attitude of the institutions of the European Union toward CFC legislation. Special attention in this paper is focused on Judgment of the Court of Justice of the European Union in the case Cadbury Schweppes. The aim of the paper is to analyze CFC legislation in the Member States in order to determine its basic characteristics, as well as to determine its compatibility with freedoms guaranteed by the primary law of the European Union, i.e. with Judgment of the Court of Justice of the European Union in the Cadbury Schweppes case.

  19. Peces del Noroeste del Ecuador

    OpenAIRE

    Barriga, Ramiro

    1994-01-01

    La ictiofauna del occidente del Ecuador es poco conocida. Los peces del noroccidente son diferentes a los del suroccidente del Ecuador. 34 familias y 82 especies fueron colectadas que equivale al 11 % de las especies de peces continentales registradas en el Ecuador. Icteogeográficamente se sabe que la costa ecuatoriana posee dos provincias: la del Pacifico Norte y la del Guayas, se determinó que el límite de las dos provincias es el río Santiago ya que las especies del mencionado río so...

  20. Vocational Training in the European Union

    Directory of Open Access Journals (Sweden)

    Mehmet BALCI

    2013-01-01

    Full Text Available European Union requires some standards in all areas. Today, the importance of training qualified individuals which holds an important place in the development of countries increases and certain standards are adopted creating common European Union tools in the field of vocational and technical education. In this study, vocational education and training policies system and the standards adopted by the European Union are discussed. Furthermore, this study was accepted as a European Union project in 2010 and the results obtained from the Leonardo Da Vinci Life Learning European Union project called “Web Based Basic Vocational Training” between the years 2010-2012 were presented. Since the partners of these projects are Turkey, Spain and Germany, the structure of vocational education, institutions of public and private vocational education and the diplomas and certificates entitled after these educations are included. As Turkey is on its way to become a European Union member, a number of advices are presented for Turkey to reach its destination about vocational education standards that European Union has aimed. The purpose of the study is not only to be a guide for the young who want to get professional training in the countries that are European Union members or candidates about how and where to have education opportunities but also to give a chance for trainers and training managers, participating in vocational training, so as to glimpse different practices from different countries and compare these practices between the countries of European Union and their countries. The study is also very important as it has the opportunities for training managers to see if their countries' vocational education is close enough to vocational education in European Union.

  1. El costo de la atención médica del cáncer mamario: el caso del Instituto Mexicano del Seguro Social The health care costs of breast cancer: the case of the Mexican Social Security Institute

    Directory of Open Access Journals (Sweden)

    Felicia Marie Knaul

    2009-01-01

    Full Text Available OBJETIVO: Calcular el costo de atención de las pacientes con cáncer de mama tratadas en el Instituto Mexicano del Seguro Social. MATERIAL Y MÉTODOS: A través del Sistema de Información Médico Operativa del IMSS, se conformó una cohorte de pacientes con diagnóstico reciente en 2002 que recibió seguimiento hasta finales de 2006. Se identificó el uso de recursos y se le adjudicó el costo de atención del IMSS. RESULTADOS: Sólo 14% se diagnosticó en fase I y 48% en las fases III-IV. El costo de atención promedio por año-paciente se estimó en 110 459 pesos y para las mujeres diagnosticadas en 2002 la etapa I tuvo un costo de 74 522 pesos, comparado con 102 042 en la etapa II, 154 018 en la etapa III y 199 274 en la IV. CONCLUSIONES: El cáncer mamario representa un presupuesto significativo en el IMSS y entre más tardía es la etapa de detección, más altos resultan los costos económicos por año-paciente y más baja la probabilidad de sobrevida a cinco años.OBJECTIVE: We studied the cost of health care for women with breast cancer treated at the Mexican Social Security Institute (IMSS, per its abbreviation in Spanish. MATERIAL AND METHODS: Using the Medical and Operative Information Systems of the IMSS, we constructed a cohort of patients diagnosed in 2002 and followed these patients to the end of 2006, identifying the use of resources and imputing the IMSS-specific cost structure. RESULTS: Only 14% of women were diagnosed in stage 1 and 48% were diagnosed in stages III-IV. The average cost of their medical care per patient-year was $MX110,459. Costs for stage 1 were $MX74,522 compared to $102,042 for stage II, and were $MX154,018 for stage III and $MX199,274 for stage IV. CONCLUSIONS: Breast cancer accounts for a significant part of the IMSS health budget. Later stage at diagnosis is associated with higher economic costs per patient-year of treatment and lower probability of five-year survival.

  2. Discerning The Motivational Basis For Trade Unionism In Public And ...

    African Journals Online (AJOL)

    Discerning The Motivational Basis For Trade Unionism In Public And Private ... private businesses are very clear to the actors of industrial relations; those of their ... selfish interests; unions in the public sector ought to function as uplift unions, ...

  3. IMPORTANCE OF THE EUROPEAN BANKING UNION NEW DIRECTIVES

    OpenAIRE

    MEDAR LUCIAN-ION; Irina-Elena Chirtoc

    2014-01-01

    European Banking Union has set new rules on monetary market especially for credit institutions and for financial banking groups in general. Economic and monetary union requires accomplishment of political and monetary union and democratic control of the European institutions on a single financial market. In this respect through its management organisms, EU has designed a series of unique mechanisms of financial union and called for a fiscal union. Union of European financial marke...

  4. TRADOC Union List of Periodicals.

    Science.gov (United States)

    1988-08-01

    0161-119. Apr 1986+ TSD 1979+ Cuadernos del Tercer Mundo TTY Mar 1985 - Cuba Internacional TSL 0011-2593 Current 12 issues only Cuban News and Propaganda...Australiir. Journal of Political History TSQ 198 4. Austr ,I] .liiw utl,-cAk Ti& ?r, 1-9913 1963+ Auto Wee!, TRW current issues ori] Aut ob d.\\ TTX...Consumer Guide Auto Series TTH current year onil Consumer Guide Investment Series TTH current year only Consumer News (Publication ceased in 1979) TRW Apr

  5. Acquired Credit Unions: Drivers of Takeover

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    R. Raymond Sant

    2015-08-01

    Full Text Available In this paper we study acquired credit unions and analyze their financial performance up to six years prior to merger, on a quarterly basis. The primary focus is on balance sheet (asset liability management and profitability variables (return on assets. We find that acquired credit unions during the period 2008 (third quarter to 2014 (first quarter experienced negative return on assets for several quarters prior to their takeover. This was the result of a declining loan portfolio and increasing charge offs. In spite of decreasing lending activity, such credit unions continued to increase their deposits, i.e., adding to their cost base. Due to declining loans, their net interest margin as a proportion of deposits was also in decline. We argue that this is an indicator of poor management ability. Furthermore, our analysis finds that operating expenses were increasing over time, something that has been documented in previous literature also for smaller credit unions and is attributable to lack of economies of scale. The average asset size of the acquired credit unions in our sample is about $22 million just before acquisition. We attribute our findings to poor business strategy followed by such credit unions. We also conclude that signs of trouble are evident up to two years before merger on average and regulatory policy may have to become more proactive to manage the consolidation challenge faced by the credit union industry in general.

  6. Morphology as the starting point for individualized cancer treatment; La morfologia como punto de partida del tratamiento oncologico individualizado

    Energy Technology Data Exchange (ETDEWEB)

    Sanz Ortega, J.

    2009-07-01

    Historically, the histopathological diagnosis has been essential for the proper treatment of cancer. Today, in the new era of individualized cancer treatment, pathologists acquire a new role for identifying therapeutic targets, detection of hereditary syndromes; to select the most suitable molecular technique for each sample or to assess individual response to neoadjuvant therapy. The objective of this review is to show how we must combine and integrate new gross examination, microscopic and immunohistochemical data with molecular pathology, taking the example of colorectal cancer. Immunohistochemistry for DNA repair genes, the study of K-ras mutations and circumferential resection margin in rectal adenocarcinoma are part of this new reality. Therefore, besides making the correct diagnosis and staging of the tumor, we can play a key role in risk stratification of cancer and individualized treatment. Integration of the molecular study with the morphology and clinical data by pathologists may improve the efficiency of genetic tests and save costs. Phenotype precedes genotype in the clinical management algorithm of the disease. (Author) 19 refs.

  7. Church unions and their consequences in Poland

    Directory of Open Access Journals (Sweden)

    Antoni Mironowicz

    2014-11-01

    Full Text Available Orthodox Christians in Poland have faced numerous attempts to be forced into union with the Roman Catholic Church, ranging from the thirteenth to the twentieth century. The first attempt at a union between the Roman Catholic Church and the Orthodox Church took place as early as the mid-thirteenth century. Another attempt at forcing the Orthodox Church into union with Rome took place during the reign of Ladislaŭ II Yagiello. The problem of church union returned in the reign of Alexander the Yagiellonian. When Ivan III rejected all projects for bringing the Florence such a union into practice, discussion on church union disappeared until the end of the sixteenth century. The mission of the papal legate, Father Antonio Possevino, to Ivan IV, had been intended to draw Moscow into the union, and its failure caused the papacy to concentrate its efforts on the Orthodox Church in Poland. The Ruthenian bishops’ obedience to the Pope was officially announced on the 8 October 1596. The decisions of the Uniate-Catholic synod were met with numerous protests from the Orthodox clergy and nobility. The larger part of the clergy and the faithful, together with bishops remained in the Orthodox camp. Despite the failure of the Brest Synod in fully uniting Orthodox and Roman churches, new union projects concerning the Orthodox Church in Poland continued to arise prior to the end of 18th century. The Vatican’s interest in the Orthodox Church in Central Europe was renewed at the end of the First World War. On April 1st, 1917, the Pope created the Congregation for the Oriental Churches which was responsibile for all issues relating to the activities of all the Eastern denominations. Despite aims at unification, attempts at church union have had a negative influence on the relations between the Roman Catholic and Polish Orthodox Church in contemporary Poland. The result of centuries of attempts at unification under the Pope has been fragmentation and division.

  8. Control del cáncer cervicouterino en Colombia: la perspectiva de los actores del sistema de salud Control of cervical cancer in Colombia: the perspective of the health system

    Directory of Open Access Journals (Sweden)

    Carolina Wiesner-Ceballos

    2009-01-01

    tamizaje. Se requiere un programa integrado y mejor organizado en el que participen los diferentes actores del sistema de salud.OBJECTIVES: To characterize the health system stakeholder's perspective on the basics of the political, economic, and sanitary context, as well as the ways in which control activities are being realized in four of Colombia's health departments. METHODS: This was a qualitative study of four Colombian health departments chosen for their differing cervical cancer mortality rates and their planned disease control efforts (Boyacá, Caldas, Magdalena, and Tolima. Semistructured interviews were conducted of health care managers, insurance coordinators, and public and private health institutions at the departmental and municipals levels. Focus groups comprised of professionals from health insurance companies and health care services providers were convened. Data analysis was based on the grounded theory with open codes related to the roles of health care managers, insurance companies, and heath care services provided. The technical reports were compared to the testimonies of interviewees. RESULTS: Thirty-eight interviews and 14 focus groups (70.9% response rate were conducted and 12 technical reports reviewed. Cervical cancer is not perceived to be a public health priority. Interest centers on the flow of financial resources within the health system. Findings indicated unsatisfactory communication among the stakeholders and no consensus on the subject. Planning is limited to meeting the status quo. Staffing is inadequate. Cases with positive outcomes are lost to follow-up due to the fragmentation that results from affiliation with different health care systems. CONCLUSIONS: The financial situation, normative planning, and the challenges of decentralization affect the skill-building, at-risk coverage, and the control activities needed for effective screening programs. What is needed is an integrated, more efficiently organized program in which all the

  9. The European Union in International Financial Governance

    Directory of Open Access Journals (Sweden)

    Niamh Moloney

    2017-01-01

    Full Text Available This article considers the role of the European Union in international financial governance after the institutional reforms it undertook in connection with the global financial crisis. It suggests that the new administrative actors that support the governance of the European Union's single financial market, notably the European Supervisory Authorities, have the potential to reshape how the European Union engages with international financial governance. It finds that the European Union’s effectiveness in influencing international financial governance—and the effectiveness of international financial governance more generally—is likely to strengthen as a result.

  10. Coverage and focus of a cervical cancer prevention program in southern Brazil Cobertura y concentración poblacional de un programa para la prevención del cáncer cervicouterino en el sur del Brasil

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Temes de Quadros

    2004-10-01

    Full Text Available OBJECTIVE: To determine the coverage and focus of cervical cancer screening (Pap smears in a population-based sample in Brazil. METHODS: Cross-sectional cluster survey covering 1 730 women aged 20 years or older with a history of sexual activity. Information was collected on social, demographic and behavioral variables, knowledge of and use of the Pap test. RESULTS: Of women aged 25-59 years, who are the target population of the national cervical cancer screening program, 78.7% had had at least one Pap test in their lifetime, and 68.8% had had a Pap test in the last 3 years. Statistics for focus of the program showed that of the 637 women who reported having a Pap test in the last year, only 20.6% actually required one. The remainder were either outside the age range or had had another test less than 30 months previously. Prevalence of not having been tested in the previous 3 years was highest among black (41.7% and low-income women (64.3%, and among those at greatest risk for cervical cancer (62.3% for women with three or more risk factors. Focus was inversely related to socioeconomic status. CONCLUSION: Coverage rates were similar to those reported in other national studies, but this is the first report to examine the focus of the national program. We show that 8 of every 10 Pap tests were not necessary. Coverage levels remain unacceptably low among women of low socioeconomic status and those at greatest risk for cervical cancer.OBJETIVO: Determinar la cobertura y la concentración poblacional del tamizaje del cáncer cervicouterino (con la prueba de Papanicolaou en una muestra poblacional en el Brasil. MÉTODOS: Encuesta transversal por conglomerados en una muestra de 1 740 mujeres de 20 años de edad o mayores con antecedentes de actividad sexual. Se recogió información acerca de las características sociales, demográficas y conductuales de estas mujeres, y sobre su familiaridad con la prueba de Papanicolau y la frecuencia con la que se

  11. Segurança do paciente em cirurgia oncológica: experiência do Instituto do Câncer do Estado de São Paulo Seguridad del paciente en cirugía oncológica: experiencia del Instituto del Cáncer del Estado de São Paulo Patient safety in oncology surgery: experience of the São Paulo State Cancer Institute

    Directory of Open Access Journals (Sweden)

    Regiane Cristina Rossi Vendramini

    2010-09-01

    efectuados 1019 procedimientos quirúrgicos, sin registro de error o evento adverso. La implantación del PU-JCAHO es simple, y es una herramienta útil para prevenir errores y eventos adversos en el quirófano.Patient safety concerns in surgery are increasing. The frequency of surgery-related adverse events and errors is high, and most could be avoided. The Joint Commission on Accreditation of Healthcare Organizations (JCAHO proposed the Universal Protocol (UP-JCAHO for preventing wrong site, wrong procedure, and wrong person surgery. In Brazil, very few health-care institutions have adopted this Protocol. Thus, there is a need to improve its dissemination and assess its effectiveness. The aim of the present study was to report the experiences of the Sao Paulo State Cancer Institute (ICESP, acronym in Portuguese in implementing the UP-JCAHO. The Protocol comprises three steps: pre-operative verification process, marking the operative site and Time out immediately before starting the procedure. The ICESP surgical center (SC has been functioning since November 2008. The UP-JCAHO is applied to all surgeries. A total 1019 surgeries were performed up to June 2009. No errors or adverse events were registered. The implementation of the UP-JCAHO is simple. It can be a useful tool to prevent error and adverse events in SC.

  12. Responsabilidad individual en la detección temprana del cáncer de próstata Individual responsibility in early detection of prostate gland cancer

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    Ramón Lemay Nodal Laugart

    2011-07-01

    Full Text Available Teniendo en cuenta que la tasa de morbilidad y mortalidad por cáncer de próstata ha ido aumentando en Santiago de Cuba, los autores de este trabajo decidieron analizar lo relacionado con la responsabilidad individual para detectar precozmente esa afección; por tanto, para determinar los factores que incidían en la baja percepción del riesgo, en los primeros meses de 2011 se encuestó acerca de ello a 48 hombres mayores de 50 años, pertenecientes al área de salud del Policlínico Universitario "Frank País García" de Santiago de Cuba. Los resultados pusieron de manifiesto la imperiosa necesidad de realizar acciones de promoción sanitaria y prevención de enfermedades, con vistas a lograr que el individuo se sienta cada vez más responsable del cuidado de su propia salud, puesto que 85,4 % de los integrantes de la casuística admitieron no haberse sometido a exámenes para garantizar el diagnóstico temprano de ese tipo de tumor o descartar su presencia.Starting from the point that morbidity and mortality rate due to prostate gland cancer has increased in Santiago de Cuba, the authors of this work decided to analyze the relation to individual responsibility in order to early detect the aforementioned condition. Therefore, 48 men over 50 years old belonging to the health area of "Frank País García" University Polyclinic in Santiago de Cuba were surveyed during the first months of the year 2011 to determine the factors that influenced on the low risk perception. Results showed the urgent need of carrying out actions of health promotion and disease prevention in order to achieve the individual feels more responsible of his health care. Of the case material, 85,4 % participants admitted they did not have the tests to guarantee the early diagnosis or detect this tumor.

  13. Trade Union Cooperation in the EU: Views Among Swedish Trade Unions and Their Members

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    Bengt Furåker

    2013-09-01

    Full Text Available This article compares views among Swedish trade unions with those of their members regarding cross-national union cooperation in Europe or the EU. Data are derived from two different surveys, one among trade unions in 2010–2011 and the other among employees in 2006. It turns out that trade unions are generally more affirmative than their members to transnational union cooperation. In the employee survey, differences appear between members of the three peak-level organizations—the LO (manual workers, the TCO (white-collar workers, and Saco (professionals. However, controlling for education, these differences cannot be verified statistically. Higher education—which above all Saco members have—is linked to more positive attitudes toward transnational union cooperation. The gap between the organizations and their affiliates concerning engagement in European issues appears to be larger in the LO than in Saco, with the TCO somewhere in the middle.

  14. Bases genómicas del cáncer de mama: avances hacia la medicina personalizada Genomic basis for breast cancer: advances in personalized medicine

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    Alfredo Hidalgo-Miranda

    2009-01-01

    Full Text Available El análisis genómico del cáncer de mama ha permitido el desarrollo de nuevas herramientas de predicción de riesgo y respuesta al tratamiento en esta enfermedad. Los perfiles de expresión génica han generado una mejor clasificación de los tumores e identificado subgrupos tumorales con características clínicas particulares. También se han reconocido patrones de pérdida y ganancia de DNA y expresión de micro-RNA relacionados con la carcinogénesis mamaria, tras identificar nuevos blancos potenciales. Los estudios de asociación del genoma completo han identificado variantes genéticas vinculadas con un mayor riesgo a presentar esta enfermedad, lo que hará posible tomar decisiones de salud pública mejor fundamentadas. Asimismo, los avances en la tecnología de secuenciación de DNA permitirán obtener información acerca de todas las alteraciones genéticas en los tumores. En esta revisión se describe el estado que guarda la investigación genómica en el cáncer de mama, así como la transición de estos hallazgos a la práctica clínica y la creación de las bases para el desarrollo de la medicina personalizada.Genomic analysis of breast cancer has allowed the development of new tools for the prediction of recurrence and the response to treatment of this disease. Gene expression profiles allow better tumor classification, identifying tumor subgroups with particular clinical outcomes. New potential molecular targets involved in breast carcinogenesis have also been identified through the analysis of DNA copy number aberrations and microRNA expression patterns. Whole genome association studies have identified genetic variants associated with a higher risk to develop this tumor, providing more information for public health decisions. Progress in DNA sequencing methods will also allow for the analysis of all the genetic alterations present in a tumor. In this review, we describe the current state of genomic research in breast cancer as

  15. Children's Literature in the Soviet Union

    Science.gov (United States)

    Miller, D. D.; And Others

    1976-01-01

    Children's literature in the Soviet Union is of four types: 17 stories based on old tales, adaptations from great Russian literature, original writings for children, and translations from foreign works. (JH)

  16. Former Soviet Union (FSU) Gravity Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Gridded gravity anomaly data for the Former Soviet Union (FSU) and Eastern Europe has been received by the National Geophysical Data Center(NGDC). The data file...

  17. Growing Up Gifted in the Soviet Union.

    Science.gov (United States)

    Stevens, Robert E.

    1987-01-01

    A review of the educational program for gifted students in the Soviet Union discusses student responsibilities, program admission, and specialized schools featuring foreign languages, mathematics and physics, music, ballet and arts, sports, and "little academics" (advanced studies). (CB)

  18. The public control of credit unions

    Directory of Open Access Journals (Sweden)

    Alberto García Müller

    2006-12-01

    Full Text Available Public control is the activity of investigation or review by the government takes over a company, to verify the conformity of its actions to law. This paper analyzes the control over credit unions.

  19. Surgery of the cancer of Uterine Neck Past, present and Future; Cirugia del Cancer de cuello Uterino. Pasado, presente y futuro

    Energy Technology Data Exchange (ETDEWEB)

    Escudero Fernandez, M.

    2009-07-01

    The evolution of the surgery of the cancer of cervix has passed for several stages. First the boarding was indisputably vaginal. Thanks to the anestesea, antibioterapia and transfusion was produced a change that has come to our days to the abdominal route with Wertheim Meigs's intervention. From 1987 Dargent he introduced the route laparoscopica, the conservative surgery and the return to the vaginal boarding. Today the robotic surgery is imposed with the Da Vinci. (Author) 16 refs.

  20. Endoscopic, epidemiologic and clinic characterization of the colorectal cancer in geriatric patients;Caracterizacion clinica, epidemiologica y endoscopica del cancer colorrectal en pacientes geriatricos

    Energy Technology Data Exchange (ETDEWEB)

    Umpierrez Garcia, Ibis [Hospital Militar Docente ' Dr Mario Munnoz Monroy' , Matanzas (Cuba); Norma, Herrera Hernandez [Hospital Universitario Clinico-Quirurgico ' Cmdte Faustino Perez Hernandez' Matanzas (Cuba); Hernandez Ortega, Ania [Hospital Territorial Docente ' Mario Munnoz Monroy' , Municipio de Colon, Matanzas (Cuba)

    2009-07-01

    The colorectal cancer is a serious health problem because of its high incidence. In Cuba, this disease is the fourth neoplasm in order of frequency with a rate of 17.1 per 100 000 inhabitants. With the objective of determining the precocious diagnosis of this complaint we carried out a prospective, longitudinal and descriptive study among geriatric patients with colorectal disease assisting to consultation at the policlinic 'Carlos Verdugo' of Matanzas in the period from January 2006 to December 2007. The studied parameters were age, genre, risk facts, presentation forms, localization, and endoscopic diagnosis of the disease. The results showed predominance of female sex (52,1 %), in ages from 60 to 69 years old (59.3 %), predominating risk facts like familiar antecedents (13,5 %), idiopathic ulcerative colitis (8.1 %), and an inadequate diet (35.1 %). The most used diagnostic method was colonoscopy (18 patients), with predominance of the rectosigmoidal cancer (15 cases), being the polypoid one the most common endoscopic kind (13 %). We concluded that generally there is not a precocious diagnosis of the colorectal cancer among geriatric patients, leading to a decrease of the healing possibilities and surviving of these patients

  1. O significado do tabagismo no contexto do câncer de laringe El significado del tabaquismo en el contexto del cáncer de laringe The meaning of smoking within the context of larynx cancer

    Directory of Open Access Journals (Sweden)

    Flávia Tatiana Pedrolo Hortense

    2008-02-01

    Full Text Available Este estudo qualitativo objetivou compreender crenças e valores estabelecidos na relação entre câncer de laringe e tabagismo utilizando a estratégia do Discurso do Sujeito Coletivo. Participaram três pacientes, três profissionais de saúde e três familiares. Os dados foram coletados por meio de entrevistas semi-estruturadas. A análise identificou as categorias: história do tabagismo; busca por ajuda para sua doença; saúde, câncer de laringe e tabaco; cuidado familiar e cuidado profissional. O estudo demonstrou a necessidade de ampliar o foco de atuação dos profissionais acrescentando na formação desses trabalhadores paradigmas das ciências humanas visando contribuir para mudanças comportamentais no que diz respeito às orientações de saúde sobre os hábitos e/ou estilos de vida dos usuários dos serviços de saúde e seus familiares.El objetivo de este estudio cualitativo fue comprender las creencias y valores establecidos sobre la relación entre el cáncer de laringe y el tabaquismo utilizándose la estrategia del Discurso del Sujeto Colectivo. En el estudio participaron tres pacientes, tres profesionales de la salud y tres familiares. Los datos fueron colectados por medio de entrevistas semi-estructuradas. El análisis de los datos identificó las siguientes categorías: historia de tabaquismo; la busca por ayuda para la enfermedad; salud, cáncer de laringe y tabaco; cuidado familiar y cuidado profesional. El estudio demostró la necesidad de ampliar el foco de la actuación de los profesionales acrecentándose a la formación de estos trabajadores los paradigmas de las ciencias humanas con el objetivo de contribuir para mudanzas de comportamiento relacionadas a las orientaciones de salud sobre los hábitos y/o estilos de vida de los usuarios de los servicios de salud y de sus familiares.The objective of this qualitative study was to understand beliefs and values established as to the relation between larynx cancer and

  2. Radioactive waste management in European Union countries

    International Nuclear Information System (INIS)

    Vico, E.

    2002-01-01

    Although the Euratom Treaty does not assign direct authorities to the European Union in the Field of radioactive waste, the Commission has developed a series of activities related to this type of waste. The article deals with these Community initiatives, and the problems of radioactive waste management in the different Member States, and future plans in the field in the light of forthcoming European Union enlargement in 2004. (Author)

  3. Does union membership really reduce job satisfaction?

    OpenAIRE

    Alex Bryson; Lorenzo Cappellari; Claudio Lucifora

    2003-01-01

    We investigate the effect of union membership on job satisfaction. Whilst it is common to study the effects of union status on satisfaction treating individual membership as given, in this paper, we account for the endogenous selection induced by the sorting of workers into unionised jobs. Using linked employer-employee data from the 1998 British Workplace Employee Relations Survey, we address the question of how the membership decision is related to overall job satisfaction and to satisfacti...

  4. Taxation of credit unions in Ukraine

    Directory of Open Access Journals (Sweden)

    Оксана Георгіївна Волкова

    2015-10-01

    Full Text Available The article deals with the issues of income taxation of credit unions in Ukraine by the tax on profits of enterprises and tax of revenues of their members accrued on the interest of contributions (deposits on deposit accounts and mutual funds the tax to incomes of physical persons. The consequences of the influence of tax rules on capitalization of unions and the level of their financial support is defined

  5. European Union security policy through strategic culture

    Directory of Open Access Journals (Sweden)

    Beriša Hatidža

    2014-01-01

    Full Text Available In this paper, we shall pay attention to the security policy of the European Union, through the strategic culture, starting from the existing various options for cooperation in the field of security and defense. Our goal is to look at the implementation of the Strategic Culture of the European Union (EU SK, research ways to improve the international position of the Union and its impact on policy cooperation and trust with other collectives. Analysis of flexible cooperation between the European Union, as well as access to special procedures in the field of security and defense policy, we will follow the ambition and capacity in implementing the same. Paper aims to introduce the idea of the European Union, which allows its members to rationally consider and check the box of options available to decision makers. In this regard, the EU seeks to build its own armed forces to protect the association of interests-investment terms. Reviewing and understanding the strategic culture of the EU by countries that are not its members can be seen as reasons for strengthening the capacity of the Union for the realization of the impact of the global security as well as predicting its future steps.

  6. Labor unions and safety climate: perceived union safety values and retail employee safety outcomes.

    Science.gov (United States)

    Sinclair, Robert R; Martin, James E; Sears, Lindsay E

    2010-09-01

    Although trade unions have long been recognized as a critical advocate for employee safety and health, safety climate research has not paid much attention to the role unions play in workplace safety. We proposed a multiple constituency model of workplace safety which focused on three central safety stakeholders: top management, ones' immediate supervisor, and the labor union. Safety climate research focuses on management and supervisors as key stakeholders, but has not considered whether employee perceptions about the priority their union places on safety contributes contribute to safety outcomes. We addressed this gap in the literature by investigating unionized retail employee (N=535) perceptions about the extent to which their top management, immediate supervisors, and union valued safety. Confirmatory factor analyses demonstrated that perceived union safety values could be distinguished from measures of safety training, workplace hazards, top management safety values, and supervisor values. Structural equation analyses indicated that union safety values influenced safety outcomes through its association with higher safety motivation, showing a similar effect as that of supervisor safety values. These findings highlight the need for further attention to union-focused measures related to workplace safety as well as further study of retail employees in general. We discuss the practical implications of our findings and identify several directions for future safety research. 2009 Elsevier Ltd. All rights reserved.

  7. Incidencia del cáncer de tiroides en la consulta central de tiroides, últimos nueve años en Pinar del Río Incidence of cancer in the thyroid gland. Its behaviour at central medical consultation during 1998-2007 Pinar del Rio

    Directory of Open Access Journals (Sweden)

    Gladys Iglesias Díaz

    2008-06-01

    Full Text Available Se realizó un estudio observacional clínico de caso paciente, retrospectivo, descriptivo y de corte transversal, en un universo de 679 enfermos intervenidos quirúrgicamente por afecciones de la glándula tiroides en " Hospital León Cuervo Rubio" , para evaluar la frecuencia con que se presenta el cáncer de tiroides en la consulta central de tiroides de Pinar del Río. Durante los últimos nueve años, se seleccionó una muestra de 104 portadores de cáncer de tiroides diagnosticados por la biopsia por parafina en el departamento de Anatomía patológica del mismo Hospital, entre los años 1999 al 2007. Se procesaron variables cualitativas y cuantitativas como número de casos por año, variedad histológica y otras, y se representaron en tablas y gráficos, se determinó que el 15% del universo sufre de cáncer de tiroides. El carcinoma bien diferenciado fue la variedad histológica que predominó (96 %, en ocasiones se asociaban con otras enfermedades, predominando la tiroiditis de Hashimoto, el indiferenciado toma valores por encima de lo normal con el 3,8 %, se refiere un caso de carcinoma folicular el resto se representa por la variedad papilar.A clinical, retrospective, descriptive, cross-sectional case report study was carried out at "Leon Cuervo Rubio" General Hospital, taking a total of 679 patients who underwent a surgery of thyroid gland during the last 9 years. A sample of 104 patients who suffered from cancer of the thyroid was selected - being this corroborated by means of paraffin wax biopsies. These biopsies were performed at the Department of Anatomy in the institution during 1999-2007. Qualitative and quantitative variables and the figures of cases per year were processed, histological variety and other items were represented in tables and charts. 15% of the total of patients suffered from cancer of thyroid, histologically the differentiated carcinoma prevailed (96%, and sometimes it was associated with other diseases

  8. Cancer

    Science.gov (United States)

    Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms ... be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors ...

  9. [Female nuptiality: the importance of consensual unions].

    Science.gov (United States)

    Ojeda, N

    1988-01-01

    Mexico's National Demographic Survey of 1982 indicated that 58.4% of ever married women had been in marriages celebrated both civilly and religiously, 24.4% had been in civil marriages only, 3.0% had been in religious marriages only, and 14.2% had been in consensual unions. Transitions from 1 type of union to another by the same couple are very common, however. 53.6% of women began their conjugal lives in civil and religious marriages, 19.3% in civil marriages only, 2.3% in religious marriages only, and 24.6% in consensual unions. About 1/2 of consensual unions are eventually legalized, but the rate is lower in the less advantaged socioeconomic sectors which have a higher proportion of consensual unions. Corrected data show that only 7.5% of Mexican women remain single at the age of 45. The average age at 1st union is 21.4 years. Marriage patterns differ significantly in different social sectors. The proportion of women consensual unions varied from 16.1% for the new bourgeoisie, defined as administrators, technicians, high-level workers, and professional public officials, to over 30% for nonsalaried workers, peasants, and agricultural wage workers. Peasants, agricultural wage workers and nonagricultural nonsalaried workers had the lowest marriage ages and the highest proportion married by age 20. In the various proletarian groups, only 2.8-3.7% remained single at age 45, and 42.5%-51.3% were married or in union by age 20. Proletarian women had intermediate ages at 1st marriage. Women of the new bourgeoisie had the highest age at 1st union, 23 years, but the lowest proportion single at age 45, 1.8%. The traditional bourgeoisie and new bourgeoisie had the 2nd lowest age at 1st union, 21.9, and a proportion never married at age 45 that was similar to the national average. The proportion single at age 45 was highest among peasants and agricultural wage workers, reaching 11.3%.

  10. Trade Union Mergers: A Survey of the Literature.

    Science.gov (United States)

    Michelson, Grant

    2000-01-01

    Examines trade union mergers highlighting merger forms, merger motivation, role played by union officers, and merger waves. Discusses the consequences of mergers on members and union performance and concludes that union merger activity has had little impact. (Contains 74 references.) (JOW)

  11. Colorectal cancer clinical epidemiological characteristics in patients attended at Oncology service; Caracteristicas clinicas epidemiologicas del cancer colorrectal en un grupo de enfermos atendidos en consulta de Oncologia

    Energy Technology Data Exchange (ETDEWEB)

    Area Abreu, Daniel; Borrego Pino, Luis; Borrego Diaz, Luis; Abreu Rivera, Pedro; Garrote, Tillan; Aurora, [Hospital Provincial ' Vladimir Ilich Lenin' , Holguin (Cuba)

    2009-07-01

    A study of series of cases from January 2006 to December 2007 was carried out in 195 patients with colorectal cancer. They were attended at Oncology Service at Lenin Hospital, and were diagnosed at different health areas of the province. 63% and 37% of them had tumors in rectum and colon respectively. The age group between 40 and 69 years old was the most affected one (81.0%) and 56.9% of them were males. The main risk factors were the family history of the illness, chronic constipation, bleeding polyps and vesicular lithiasis. The most frequent clinical manifestations were rectal hemorrhage and anemia. (author)

  12. Method for automatic re contouring straight adaptive radiotherapy for prostate cancer; Metodo para el recontorneo automatico del recto en radioterapia adaptativa en cancer de prostata

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez Vila, B.; Garcia Vicente, F.; Aguilera, E. J.

    2011-07-01

    Outline of quickly and accurately the rectal wall is important in Image Guided Radiotherapy (IGRT in the acronym) as an organ of greatest influence in limiting the dose in the planning of radiation therapy in prostate cancer. Deformabies registration methods based on image intensity can not create a correct spatial transformation if there is no correspondence between the image and image planning session. The rectal content variation creates a non-correspondence in the image intensity becomes a major obstacle to the deformable registration based on image intensity.

  13. Molecular basis of colorectal cancer: Towards an individualized management? Bases moleculares del cáncer colorrectal: ¿Hacia un manejo individualizado?

    Directory of Open Access Journals (Sweden)

    J. Perea

    2011-01-01

    Full Text Available Colorectal cancer (CRC has become a highly relevant condition nowadays. In this respect, advances in the understanding of its molecular basis are key for an adequate management. From the time when the adenoma-carcinoma sequence was formulated as a carcinogenesis model to this day, when, among other things, three major carcinogenic pathways have been identified, the CRC concept has evolved from that of a single disease to the notion that each CRC is a differentiated condition in itself. The suppressor or chromosome instability pathway, the mutator or microsatellite instability pathway, and the methylator or CpG island methylation pathway allow various phenotypes to be identified within CRC. Similarly, the presence of different changes in certain genes confers several behaviors on CRC from both the prognostic and responsive standpoints to specific therapies. However, this apparent complexity does help develop the clinical management of this disease through the identification of novel, more specific therapy targets, and also markers for various behaviors within the condition, which will most likely lead us to an individualized management for these patients.La importancia que está adquiriendo el cáncer colorrectal (CCR hoy en día es importantísima. En este sentido, los avances en el conocimiento de sus bases moleculares son esenciales para su adecuado manejo. Desde la formulación del modelo de carcinogénesis de la secuencia adenoma-carcinoma hasta hoy, en que, entre otros aspectos, se han identificado tres grandes vías de carcinogénesis, el concepto de CCR ha llegado a transformarse desde el de una enfermedad única a la idea de que cada CCR es una entidad diferenciada respecto al resto de CCR. La vía supresora o de la inestabilidad cromosómica, la vía mutadora o de la inestabilidad de microsatélites, y la vía metiladora o del fenotipo metilador de islas CpG, permiten identificar diferentes fenotipos dentro del CCR. De la misma forma

  14. Occult blood test and colonoscopy in the diagnosis of colorectal cancer; Test de sangre oculta y colonoscopia en el diagnostico del cancer colorrectal

    Energy Technology Data Exchange (ETDEWEB)

    Tusen Toledo, Yunia; Chao Gonzalez, Lissette; Barroso Marquez, Lisset [Centro Investigaciones Medicoquirurgicas (CIMEQ), La Habana (Cuba)

    2009-07-01

    A descriptive-prospective study was conducted on 212 outpatients from the Gastroenterology Service at CIMEQ's Hospital from January 2006- May 2007. These patients received an immune-chemical test of hidden blood in fecal stools and an endoscopic colon study, with the objective of determining the value of the hidden blood and colonoscopy for the detection of colorrectal cancer. Age average was 60, 6 {+-} 14,0 years, with predominance of the female sex. The main clinical condition for this study was to observe the change of intestinal habits in a 28, 3 % of patients, The test performed on hidden blood was positive in 76 patients (36,0%) and 34 (16,0%) had positive colorrectal cancer diagnosis, of which a 50% was localized at the proximal colon; 91,12% of the neoplasias were of the adenocarcinoma-type, where moderately differentiated ones predominated. A sensitiveness of a 76, 47 % and of a 71,91 % specificity were obtained when evaluating the efficacy of hidden blood in the diagnosis of neoplasias

  15. Radiotherapy treatment results of bladder cancer: study of 458 patients. Resultados del tratamiento radioterapico en cancer de vejiga: estudio retrospectivo de 458 pacientes

    Energy Technology Data Exchange (ETDEWEB)

    Vara Santos, J.; Torre Tomas, A. de la; Romero Fernandez, J.; Regueiro Otero, C.; Clavo Varas, B.; Magallan Sebastian, R.; Valcarcel Sancho, F.; Polo Tolosana, E.; Aragon de la Cruz, G.

    1994-01-01

    Between 1964 to 1990, 458 patients diagnosed of bladder cancer have been treated with radical radiotherapy in our department. The 5-years and 10-years actuarial survival rates were 37% and 27% respectively. The 5-years and 10-years actuarial local control rates, evaluated in 404 patients, were 41% and 38%. In regard to survival, T stage (p=0.013), advanced intravesical extension or multicentrity (p>0.0001), and squamous differentiation (p<0.0001), reached statistical significance as adverse prognostic factors. In 248 patients, with invasive transitional carcinoma, radical radiotherapy alone was used. In this group of patients, T stage (p=0.006) and advanced intravesical extension or multicentrity (p=0.0002) were adverse prognostic factors for survival. Our results suggest that radical radiotherapy must be considered and alternative to surgery in management of bladder cancer. On the basis of prognostic factors evidenced in this series a subgroup of patients with low probability of survival when treated with exclusive radiotherapy are defined. This patients must be included in clinical research protocols. (Author) 44 refs.

  16. The effects of union mergers and internal restructuring:

    DEFF Research Database (Denmark)

    Navrbjerg, Steen Erik; Larsen, Trine Pernille

    2016-01-01

    Trade union mergers and restructuring are often seen as strategy for union revitalisation and renewal and have been ongoing in the majority of European trade unions. This paper explores how recent union mergers and internal restructuring has affected unions service provision, union democracy...... and interest representation. This is analysed drawing on longitudinal data from two Danish shop steward surveys conducted in 1998 and 2010, comparing shop stewards in merged and non-merged unions respectively. The main results are that although it could be expected that union mergers and internal restructuring......, where union size and less so the union’s recent merger and restructuring history appears to affect shop stewards’ relations with their unions....

  17. Citizenship of the European Union under the Treaty of Lisbon

    Directory of Open Access Journals (Sweden)

    Ioana Nely MILITARU

    2011-06-01

    Full Text Available The paper is structured in two parts. The first part covers history, "Union citizenship, according to previous Treaties Lisbon Treaty, and the second refers to the privileges which they have as citizens of the Union Treaty as a result of reforming the European Union, referring to documents on which this Treaty adhere it recognizes as having the same legal force, treaties, (Treaty on European Union and the Treaty on the Functioning of the European Union.

  18. Unions in small and medium-sized enterprises

    DEFF Research Database (Denmark)

    Holten, Ann-Louise; Crouch, Colin

    2014-01-01

    Trade unions are commonly weak in small- and medium-sized enterprises, which constitute a majority of European firms and are often family-owned. We investigate the influence of family ownership on employee membership, perceptions and experience with unions in Danish and Italian firms in the textile...... and clothing sector. Family ownership reduces union membership; and within family firms, the number of family members employed is negatively associated with unionization rates and employee perceptions of unions....

  19. The 1997 Protocol and the European Union (European Union and '2nd generation' responsibility conventions)

    International Nuclear Information System (INIS)

    Handrlica, Jakub; Novotna, Marianna

    2014-01-01

    The issue of accession of the Eastern European Member States to the 1997 Protocol is discussed with focus on the European Union's authority and enforcement powers. Following up the article published in the preceding issue of this journal, the present contribution analyses the relations of the '2nd generation' responsibility conventions to the law of the European Union. (orig.)

  20. Virtual OPACs versus Union Database: Two Models of Union Catalogue Provision.

    Science.gov (United States)

    Cousins, Shirley

    1999-01-01

    Considers some of the major technical and organizational issues involved in virtual-catalog production, contrasting them with the traditional union catalog approach exemplified by COPAC, an online public-access catalog composed of academic libraries in the United Kingdom. Suggest a method of integrating these two models of the union catalog.…

  1. a decade of african union and european union trans-regional

    African Journals Online (AJOL)

    Abel

    designed to link the African Union and the European Union in a process of trans- ... terrorism, drug and human trafficking and migration.5 The common value ..... have involved policing, rule of law, border assistance and monitoring and security .... Europe as exemplified by Russia and Ukraine (who provided helicopters and ...

  2. 75 FR 81378 - Fiduciary Duties at Federal Credit Unions; Mergers and Conversions of Insured Credit Unions

    Science.gov (United States)

    2010-12-28

    ... NCUA's neutrality in the final rule and has made this change. A commenter also suggested including this..., where the net worth ratio of the merging credit union exceeds the net worth ratio of the continuing... are entitled to the net worth of a merging credit union. The NCUA Board disagrees. As discussed in the...

  3. European Union: Gender and politics

    Directory of Open Access Journals (Sweden)

    Žunić Natalija

    2014-01-01

    Full Text Available Political representation is the central issue in contemporary debates on the level of democracy in political institutions and processes in the European Union. Underrepresentation of particular groups in political institutions, decision-making and policy-making processes is perceived as the problem of justice, legitimacy and effectiveness in democratic societies. In this paper, the author analyzes the gender aspects of democratic decision-making processes and political representation of women in the EU member states. The social, historical and political dimension of women's efforts to obtain and promote their civil status and political rights have been the framework for developing the principle of gender equality as one of the founding EU principles. In the past hundred years, one of the most significant trends in politics has been the expansion of formal political representation of women. Yet, even though it has been more than a hundered years since women won their political rights in the 19th and the 20th century (the right to vote and the right to be voted, gender differences in political rights are still a substantial part of debate. Today, women's political representation is still inadequate and their political capacity and power have not been exercised to a sufficient extent (or proportionally through their actual representation in parliament. In March 2012, the European Commisision published a report on gender equality in different areas of social life; the Eurobarometer survey shows that women are generally underrepresented in politics. In national parliaments, only one out of four MPs is a woman. In the European Parliament, three out of ten parliamentarians are women. The statistics shows a huge discrepancy among the EU Member States in terms of women's representation in parliament (44.7% in Sweden as contrasted to 13.3% in Romania. The prevailing view in many studies is that post-industrial democracies are deficient as they have failed

  4. Políticas públicas para la detección del cáncer de mama en México Public policies for the detection of breast cancer in Mexico

    Directory of Open Access Journals (Sweden)

    Olga Georgina Martínez-Montañez

    2009-01-01

    Full Text Available El cáncer de mama es un problema de salud pública, prioritario por su magnitud y trascendencia, que se relaciona con las transiciones demográfica y epidemiológica del país. Con el envejecimiento de la población, y una mayor exposición a los factores de riesgo, cobrará mayor relevancia en la sociedad y los servicios de salud, que deberán responder a las necesidades crecientes de detección y atención de esta tumoración mediante programas costo-efectivos. El propósito de este artículo es exponer un análisis de la mortalidad por el cáncer de mama, así como las recomendaciones internacionales con mayor consenso sobre la organización de los programas de tamizaje; por último, se presentan los aspectos medulares del programa de acción para la detección y control del cáncer de mama durante la presente administración (2007-2012. Las políticas para el control de esta neoplasia en México están dirigidas a la organización y el crecimiento de la infraestructura para el desarrollo de un programa nacional de detección temprana, diagnóstico oportuno y tratamiento con calidad óptima, trato cordial y respeto a los derechos de las pacientes.Breast Cancer is a significant public health problem associated with epidemiological and demographic transitions that are currently taking place in Mexico. Aging and increased exposure to risk factors are thought to increase breast cancer incidence, having great relevance for the society and health services. Under this scenario, the health system must respond to the growing needs for better breast cancer screening services. In this paper we present an update of breast cancer mortality, general international recommendations for breast cancer screening programs and key aspects of the Mexico Action Program for Breast Cancer Screening and Control 2007-2012. Breast cancer policies are aimed at organizing and increasing the infrastructure to develop a National Program for Detection, Diagnosis and

  5. The new architecture of the European Union

    Directory of Open Access Journals (Sweden)

    Radivojević Zoran

    2011-01-01

    Full Text Available The Lisbon Treaty has brought significant changes into the architecture of the European Union. The most important novelty, however, is the establishment of a full unity of the Union structure achieved by creating new and strengthening the existing elements. The new elements of this unity are the disappearance of the European Community, the 'independence' of the European Atomic Energy Community, constituting the European Union as a single entity and the introduction of EU values. At the same time, the Lisbon Treaty has strengthened the existing elements of the common institutional mechanisms, rules on amending the founding treaties and EU membership. However, constituting the Union as a single entity which has replaced and succeeded the European Communities has not abolished the EU elements of diversity. In the areas that differed, even before the adoption of the Lisbon Treaty, from the community pillar, there remain significant differences in the nature and the scope of competences of the Union institutions. This mainly regards the common foreign and security policy, which now includes the defense policy, where the existing model of inter-state cooperation has been only slightly interfered with. In contrast, in the field of police and judicial cooperation in criminal matters, which has become part of a larger Area of Freedom, Security and Justice, the inter-state model of cooperation has been abandoned in some of its most important elements. However, the implementation of some of the important elements of the supranational model has been postponed.

  6. Union Gas and Ontario gas production

    International Nuclear Information System (INIS)

    Cameron, C.

    2001-01-01

    A step-by-step review of the tie-in process of new production wells into the Union Gas System is described. Requirements of the producer and those of Union Gas are explained. Also described are the choices available to the producer to sell his gas. He can sell either to Union Gas directly at an agreed upon price, or the producer has the option to have what is called an M13 contract which allows him to sell his gas at Dawn, where it can be stored within parameters of the contract, and sold to any buyer at Dawn at a negotiated rate. This arrangement, while entailing a much greater administrative load than direct sale to Union Gas, nevertheless, allows the producer to take advantage of market fluctuations. A third option provided by Union Gas is to make available to the producer storage space greater than the provisions of the M13 contract at current market rate, thereby opening up the opportunity to the producer to capture additional value in later winter months (when gas is in greater demand)

  7. Effect of extra virgin olive oil components on the arachidonic acid cascade, colorectal cancer and colon cancer cell proliferation; Efecto de los componentes del aceite de oliva virgen extra en la cascada del ácido araquidónico, el cáncer colorrectal y la proliferación de células de cáncer de colon.

    Energy Technology Data Exchange (ETDEWEB)

    Storniolo, C.E.; Moreno, J.J.

    2016-07-01

    The mediterranean diet (MD) reduced the risk of colorectal cancer (CRC), and olive oil, the primary source of fat in the MD, has also been found to have a protective effect. However, animals fed with oleic acid present a high number of intestinal tumours, suggesting that oleic acid and olive oil consumption can exert different effects on CRC. Considering that extra virgin olive oil (EVOO) is a complex mix of fatty acids and minor compounds such as polyphenols, hydrocarbons, phytosterols and triterpenes; and that these compounds have antioxidant activity and consequently they can modulate the arachidonic acid (AA) cascade and eicosanoid synthesis. This review analyzes the state of the art of olive oil components on the AA cascade and cellular mechanism involved in CRC such as intestinal epithelial cell growth/apoptosis, to understand the fact that the consumption of seed oils with high oleic content or EVOO will probably have different effects on CRC development. [Spanish] La dieta Mediterranea (DM) y el aceite de oliva reducen el riesgo de cáncer colorrectal (CCR). Sin embargo, animales alimentados con dietas ricas en ácido oleico presentan un elevado número de tumores intestinales, lo que sugiere que el consumo de ácido oleico y aceite de oliva pueden tener efectos diferentes sobre el desarrollo de CCR. Considerando que el aceite de oliva extra virgen (AOEV) es una compleja mezcla de ácidos grasos y compuestos minoritarios como polifenoles, lignanos, hidrocarburos, fitoesteroles y triterpenos; y que algunos de estos compuestos son antioxidantes y modulan la cascada del ácido araquidónico (AA) y la producción de eicosanoides. Analizamos la información existente sobre el efecto de los componentes del AOEV sobre la cascada del AA y los mecanismos implicados en el CCR como el crecimiento de las células epiteliales intestinales/apoptosis, lo que nos permitirá entender por qué el consumo de aceites de semillas altos en oleico o AOEV probablemente tendr

  8. Evaluación de uniones soldadas obtenidas con fundentes fundidos desarrollados con minerales cubanos

    Directory of Open Access Journals (Sweden)

    Gilma Castellanos-Hernández

    2000-03-01

    Full Text Available En este artículo se hace una caracterización integral de las uniones soldadas obtenidas en acero ct-3, correspondientes al estudio del prototipo de fundente fundido CIS-F10 para la soldadura automática bajo arco sumergido (SAW. Se muestran los resultados del análisis químico del metal de la unión soldada, así como los ensayos mecánicos de tracción longitudinal y resiliencia, según la norma AWS A5: 17. Se incluyen además las muestras metalográficas correspondientes. Los resultados son comparables con los obtenidos empleando fundentes comerciales AS 200 y AH 348.

  9. Prospective descriptive study of the toxicity of CAPOX plan in systemic treatment of colorectal cancer; Estudio descriptivo prospectivo de la toxicidad del plan CAPOX en el tratamiento sistemico del cancer colorrectal

    Energy Technology Data Exchange (ETDEWEB)

    Aghazarian, M; Larranaga, J; Reyes, G; Heinzen, S; Ferrero, L; Lasalvia, E; Echague, P; Estevez, F; Citrin, E; Viola, A. [Instituto Nacional del Cancer, Ministerio de Salud Publica. Montevideo (Uruguay)

    2010-11-15

    In recent years, the incorporation of new cytostatic drugs to treat colorectal cancer (CRC) and adjuvant objective is to treat the disease or disseminated contributed to decrease the reoccurrence and increased overall patient survive and thus the advent of various toxicity profiles according to the scheme used. To describe the clinical and para clinical toxicity of one of the schemes more chemotherapy used for the treatment of RCC at the National Cancer Institute (INCA). METHODOLOGY: Longitudinal prospective study. An analysis was made after consideration of the direction of INCA medical records of 27 patients with CRC assisted at the service of such chemotherapy Institution in the June / 2008 - Dec / 2009. He had the free and informed consent of the patients to participate in the study, disguising personal data to protect your privacy. They are proceeded to complete the notebook data collection in order to determine the toxicity of CAPOX plan. Results: 27 patients, 11 females and 16 males were included with a 58 median age. In terms of tumor topography, 10 were right colon level 10 to level the left colon and 7 rectum level. 55.5% were stage III, stage IV 29.6% and 14.8% stage II. The 27 patients included CAPOX plan received the standard dose with a median cycles of 7. The clinical toxicities more frequent were: sensory neuropathy (66.6%), diarrhea (48.1%), hand-foot syndrome (44.4%), nausea (37%), Vomiting (29.6%), mucositis (11.1%) observed less frequently: conjunctival irritation, hyperpigmentation skin, pharynx larynx dysesthesia, alopecia, and fatigue stress angina. Concerning the haematological toxicity It emphasizes that all patients had a decrease in platelet count during treatment with 44.4% of grade 1 thrombocytopenia, was 62.9% of anemia, leucopenia and 33.3% to 37.0% of neutropenia. Single one patient had mild elevation of serum creatinine. Liver enzyme toxicity occurred in 37% TGO level - GGT, 29.6% in the TGP; 29.6% in the FA and 66.6% of patients

  10. Multidisciplinary approach and multimodal therapy in resected pancreatic cancer: Observational study Evaluación multidisciplinaria y tratamiento multimodal del cáncer de páncreas resecado: Estudio observacional

    Directory of Open Access Journals (Sweden)

    R. Morales

    2011-01-01

    Full Text Available Objective: analysis and evaluation of a multidisciplinary approach, postoperative results and survival of a group of patients with resected pancreatic cancer after a multimodal therapy. Design: descriptive, prospective and observational study. Patients: between January 2004 and December 2004, 124 patients with pancreatic cancer were evaluated. In 30 patients pancreatic resection was performed, and they are the object of this study. Results of preoperative evaluation, postoperative morbidity and mortality, and long term survival were studied. Results: diagnostic evaluation was completed in ambulatory basis in 20% of the patients. In 63% of cases, admission was done in the same day of surgery. In 3 patients (9%, tumor resection was not achieved, therefore, concordance between radiological and surgical resectability rate was 91%. Resectability rate was 24.1%. Surgical Mortality was 3.3%, with a global morbidity rate of 56.6%. Survival at one, two, three and, four years was 76.2%, 56.3%, 43%, y 27.3% respectively. Conclusions: technological development and coordination of efforts in multidisciplinary teams offer an accurate evaluation of tumor involvement, and may reduce the number of laparotomies without tumor resection. The application of a systematic and generalized multimodal treatment in pancreatic cancer is progressively showing a tendency of progressive increase in resectability and survival rates in pancreatic cancer.Objetivo: analizar la evaluación del abordaje multidisciplinario de un grupo de pacientes con cáncer de páncreas resecado, los resultados postoperatorios y la supervivencia tras la aplicación de un tratamiento multimodal. Diseño: estudio descriptivo prospectivo observacional. Pacientes: entre enero de 2004 y diciembre 2009 se evaluaron 124 pacientes con cáncer de páncreas. De ellos, se realizó la resección pancreática con intención curativa en 30 casos que constituyen el objeto del estudio. Se analizaron los

  11. Cyclicality of Wages and Union Power

    DEFF Research Database (Denmark)

    Morin, Annaïg

    This paper examines how trade unions shape the volatility of wages over the business cycle. I present a dynamic stochastic model of the labor market that integrates two main features: search frictions and trade unions. Because of search frictions, each job match yields an economic surplus...... that is shared by the bargained wage. Therefore, I can decompose the volatility of wages into two components: the volatility of the match surplus and the volatility of the worker share of the surplus. Starting from the unions' objective function, I demonstrate that, under collective wage bargaining, the worker...... share is endogenous and countercyclical. Consequently, when the economy is hit by a shock, the dynamics of the worker share partially counteract the dynamics of the match surplus and this mechanism delivers endogenous wage rigidity. The model thus sheds new insights into two business cycle features...

  12. Cyclicality of Wages and Union Power

    DEFF Research Database (Denmark)

    Morin, Annaïg

    2017-01-01

    This paper examines how trade unions shape the volatility of wages over the business cycle. I present a dynamic stochastic model of the labor market that integrates two main features: search frictions and trade unions. Because of search frictions, each job match yields an economic surplus...... that is shared between the worker and the firm. Therefore, I can decompose the volatility of wages into two components: the volatility of the match surplus and the volatility of the worker share of the surplus. Starting from the unions' objective function, I show that under collective wage bargaining, the worker...... share is endogenous and counter-cyclical. Consequently, when the economy is hit by a shock, the dynamics of the worker share partially counteract the dynamics of the match surplus, and this mechanism delivers endogenous wage rigidity. The model thus offers new insights into two business cycle features...

  13. EUROPEAN UNION POLICIES FOR CLIMATE CHANGE MITIGATION

    Directory of Open Access Journals (Sweden)

    Paul Canter

    2017-07-01

    Full Text Available Climate change is one of the most important challenges that humanity faces in the 21st century, and for the European Union, combating this phenomenon represents an important element, which is reflected both in the actions carried out in recent years, domestically and internationally, as well as in the EU policy on climate change. Within the EU, regulations were adopted, that demonstrate the importance that the Union confers to the limitation of this phenomenon, stressing at the same time the need for an integrated policy framework to ensure the security for potential investors and a coordinated approach between Member States. This paper will present recent developments for the most important policies to combat and mitigate climate change in the European Union, starting with "20-20-20" objectives, which are to be met through the package "Energy-Climate Change", continuing with 2030 and 2050 timeframes, and finally presenting the main lines of action to combat climate change.

  14. Frank Lloyd Wright in the Soviet Union

    Directory of Open Access Journals (Sweden)

    Brian A. Spencer

    2017-12-01

    Full Text Available In 1937 the First All-Union Congress of Soviet Architects was held in Moscow. The congress brought  architects from all areas of the  Soviet Union. Under the auspices of Vsesoiuvnoe Obshchestvo Kul'turnoi Sviazi s zagranitsei (VOKS it invited international architects from Europe and North and South America.  The Organizing Committee of the Union of Soviet Architects invited Frank Lloyd Wright from the United States. Frank Lloyd Wright presented his philosophy and exhibited his work, specifically his designs for the weekend home for E. J. Kaufmann "Fallingwater" and the drawings for the S.C. Johnson Administration. Frank Lloyd Wright's presentation did not focus heavily on the architecture but, rather the spirit of the Russian and Soviet vision.

  15. Some Considerations Regarding the European Banking Union

    Directory of Open Access Journals (Sweden)

    Marius Eugen Radu

    2016-09-01

    Full Text Available Union Bank is a surveillance system and an EU bank resolution, which operates on the basis of EU wide rules. It aims to ensure that the banking sector in the euro area and the EU in general is safe and reliable and viable banks benefiting from resolution without recourse to taxpayer funds and with minimal impact on the real economy. Banking union members are all euro-zone countries and EU Member States that have chosen to participate. All countries will adopt the euro in the future will automatically become members of the banking union. Countries that are not part of the euro area can join by establishing a close cooperation agreement.

  16. Bank Resolution in the European Banking Union

    DEFF Research Database (Denmark)

    Gordon, Jeffrey N.; Ringe, Wolf-Georg

    The project of creating a Banking Union is designed to overcome the fatal link between sovereigns and their banks in the Eurozone. As part of this project, political agreement for a common supervision framework and a common resolution scheme has been reached with difficulty. However, the resolution...... at the discretion of the resolution authority must be available to supply liquidity to a reorganizing bank. On these conditions, a viable and realistic Banking Union would be within reach — and the resolution of global financial institutions would be greatly facilitated, not least in a transatlantic perspective....... framework is weak, underfunded and exhibits some serious flaws. Further, Member States’ disagreements appear to rule out a federalized deposit insurance scheme, commonly regarded as the necessary third pillar of a successful Banking Union. This paper argues for an organizational and capital structure...

  17. Bank Resolution in the European Banking Union

    DEFF Research Database (Denmark)

    Gordon, Jeffrey N.; Ringe, Georg

    2015-01-01

    The project of creating a Banking Union is designed to overcome the fatal link between sovereigns and their banks in the Eurozone. As part of this project, political agreement for a common supervision framework and a common resolution scheme has been reached with difficulty. However, the resolution...... mechanism deployable at the discretion of the resolution authority must be available to supply liquidity to a reorganizing bank. On these conditions, a viable and realistic Banking Union would be within reach--and the resolution of global financial institutions would be greatly facilitated, not least...... framework is weak, underfunded and exhibits some serious flaws. Further, Member States' disagreements appear to rule out a federalized deposit insurance scheme, commonly regarded as the necessary third pillar of a successful Banking Union. This paper argues for an organizational and capital structure...

  18. Nonmarital Fertility, Union History, and Women's Wealth.

    Science.gov (United States)

    Painter, Matthew; Frech, Adrianne; Williams, Kristi

    2015-02-01

    We use more than 20 years of data from the National Longitudinal Survey of Youth 1979 to examine wealth trajectories among mothers following a nonmarital first birth. We compare wealth according to union type and union stability, and we distinguish partners by biological parentage of the firstborn child. Net of controls for education, race/ethnicity, and family background, single mothers who enter into stable marriages with either a biological father or stepfather experience significant wealth advantages over time (more than $2,500 per year) relative to those who marry and divorce, cohabit, or remain unpartnered. Sensitivity analyses adjusting for unequal selection into marriage support these findings and demonstrate that race (but not ethnicity) and age at first birth structure mothers' access to later marriage. We conclude that not all single mothers have equal access to marriage; however, marriage, union stability, and paternity have distinct roles for wealth accumulation following a nonmarital birth.

  19. Nuclear power and European Union enlargement challenge

    International Nuclear Information System (INIS)

    Chirica, Teodor; Bilegan, Constantin

    2001-01-01

    From 1991 through 1996 the European Union signed the Association Agreements with ten East European countries (EE10), namely: Czech Republic, Estonia, Hungary, Poland, Slovenia, Latvia, Lithuania, Slovakia, Bulgaria and Romania. In the period 1994-1996 European Union received membership applications from all ten countries. The paper analyzes the approach of complying the requirements and regulations for European Union accession in the field of the Romanian nuclear power based on the CANDU technology. In this process, the real challenge is represented by the preparation and implementation of new regulations aiming to improve the general business environment by introducing International Accounting Standards simplification of bankruptcy laws, reform of taxation procedures and secureness of financial instruments. A new stand-by agreement with the International Monetary Fund and World Bank was set out in late April 1999 for an one-year loan of 475 million dollars. (authors)

  20. Cancer among indigenous people in the Amazon basin of Ecuador, 1985-2000 El cáncer en la población indígena de la cuenca Amazónica del Ecuador, 1985-2000

    Directory of Open Access Journals (Sweden)

    Miguel San Sebastián

    2004-11-01

    Full Text Available OBJECTIVE: To provide some of the first data on cancer incidence among indigenous people in the Amazon basin of Ecuador, and to compare that incidence with the level found among nonindigenous persons living in that same area. METHODS: From the study area 1 207 cancer cases were reported to the National Cancer Registry over the 1985-2000 period. Frequency and relative risks were calculated for the indigenous residents and for the nonindigenous residents of the area. RESULTS: Cancer of the testes and leukemia were the most common cancer types among indigenous men, and cancer of the cervix uteri was the most common among indigenous women. Indigenous men were at significantly lower risk for cancer of the stomach, skin, prostate, and lymph nodes and for leukemia than were nonindigenous men. Indigenous women were at significantly lower risk for cancer of the stomach, skin, breast, cervix uteri, and lymph nodes than were nonindigenous women. CONCLUSION: Our data from the Ecuadorian Amazon indicate the need to develop appropriate mechanisms to register the indigenous population in the national census as well as in the National Cancer Registry. Also needed are cancer early detection programs, more health education efforts, and stronger health services that are adapted to the local conditions. Future research should focus on factors that may help to explain the different cancer patterns found among indigenous persons and nonindigenous persons.OBJETIVO: Proporcionar los primeros datos sobre la incidencia de cáncer en la población indígena de la cuenca amazónica del Ecuador y comparar dicha incidencia con la hallada en la población no indígena que habita en la misma zona. MÉTODOS: En la zona estudiada se notificaron 1 207 casos de cáncer al Registro Nacional de Cáncer en el período de 1985-2000. Se calcularon las respectivas frecuencias y riegos relativos de los residentes indígenas del territorio y de los residentes no indígenas. RESULTADOS: El

  1. The making of a European healthcare union

    DEFF Research Database (Denmark)

    Vollaard, Hans; van de Bovenkamp, Hester M.; Martinsen, Dorte Sindbjerg

    2016-01-01

    that federalism offers the most fruitful way to do so because of its sensitivity to the EU’s institutional settings and to the territorial dimension of politics. The division of competences and national diversity of healthcare systems have been major obstacles for the formation of a healthcare union. However......, the EU obtained a role in healthcare through the impact of non-healthcare legislation, voluntary co-operation, court rulings, governments’ joint-decision traps, and fiscal stress of member states. The emerging European healthcare union is a system of cooperative federalism without much cost-sharing...

  2. Transfer Pricing in the European Union

    Directory of Open Access Journals (Sweden)

    Gheorghe MATEI

    2011-04-01

    Full Text Available The transfer pricing mechanism is a tool commonly used to transfer the tax base from countries with high taxation in countries with low taxation. In the European Union, this financial operations generate significant tax revenue losses. In an attempt to limit the handling of corporate tax systems, many public authorities have introduced regulations on transfer pricing, but the effectiveness of these rules has proved limited, and they contributed to the increasing complexity of tax laws and to the appearance of additional costs for companies. A solution to the solving of the transfer pricing problem in the European Union is represented by the introduction of the common consolidated corporate tax base.

  3. The role of trade unions in Vietnam

    DEFF Research Database (Denmark)

    Torm, Nina Elisabeth

    2014-01-01

    On the basis of matched employer–employee data from 2007 to 2009, this paper examines the union wage gap among small and medium non-state manufacturing enterprises in Vietnam. Controlling for both worker and firm characteristics, the results provide evidence that union members earn higher wages t...... than non-members, and are more likely to receive social benefits.Within unionised firms, a substantial wage premium is revealed for workers employed in Southern firms, a finding which among other factors may be attributed to historical differences between the North and South of Vietnam....

  4. From Single Market to Economic Union

    DEFF Research Database (Denmark)

    Bartalevich, Dzmitry

    2014-01-01

    Book review of: From Single Market to Economic Union: Essays in Memory of John A. Usher / edited by N.N. Shuibhne and L.W. Gormley (Oxford: Oxford University Press, 2012, ISBN 9780199695706); viii + 431pp., £75.00 hb.......Book review of: From Single Market to Economic Union: Essays in Memory of John A. Usher / edited by N.N. Shuibhne and L.W. Gormley (Oxford: Oxford University Press, 2012, ISBN 9780199695706); viii + 431pp., £75.00 hb....

  5. Technique of radiotherapeutic treatment of breast cancer with scarcity means; Tecnica de tratamiento radioterapico del cancer de mama con escasez de medios

    Energy Technology Data Exchange (ETDEWEB)

    Velazquez M, S.; Carrera M, F.; Bayo L, E.; Gutierrez B, L.; Gomez-Millan B, J. [Hospital Juan Ramon Jimenez, Ronda Norte s/n, 21005 Huelva (Spain)

    1998-12-31

    The objective of this work is to show the particularities in the treatment simulation localization, in the volume selection and in the main planning strategies motive by our scarcity means during the first year of performance. It was utilized a computerized tomograph, an X-ray equipment with tele commanded table. Also it was utilized a radio opaque lattice of marked center and knowing space and also a magnetic pointer for indicating 80 cm length between focus-skin. Putting the patient on an inclined plane of self design and manufacture, it was realized three cuts at different levels over what are limited the clinical target volume (CTV) and it is optimized the isocenter through its determined localization by equations. It was employed equations for the radiobiological prediction about fibrosis and dermatitis. It was utilized another techniques or procedures for planning such as personnel wedges or the dose equilibrium in three points of the breast. It was evaluated toxicities (EORTC-RTOG). The results were as follow: Acute dermatitis (grade 1: 23 %; grade 2: 59 %; grade 3: 18 %). Acute pneumonitis (grade 1: 4.3 %); acute pharyngitis (grade 1: 11 %; grade 2: 3.7 %. In conservator treatment of breast it was obtained excellent aesthetic results in 15 %; good 72 %; moderate 11 %; and bad 3 %. The good aesthetic results by the combined use of the optimization techniques in clinical dosimetry, personnel wedges, isocenter therapy and computerized planning in the radiotherapeutic treatment of the breast cancer. (Author)

  6. Bloqueo del receptor del factor de crecimiento semejante a la Insulina Tipo I utilizando oligodeoxinucleótidos antisentido en cáncer de mama experimental Type I insulin-like growth factor receptor antisense strategies in experimental breast cancer

    Directory of Open Access Journals (Sweden)

    Mariana Salatino

    2004-04-01

    Full Text Available Evaluamos el efecto del bloqueo de la expresión del receptor del factor de crecimiento semejante a la insulina tipo I (IGF-IR sobre el crecimiento in vivo de cáncer de mama empleando una estrategia "antisentido". Utilizamos el adenocarcinoma mamario murino progestágeno-dependiente C4HD. La administración intratumoral o sistémica de oligodeoxinucleótidos antisentido fosfotiolados al ARNm del IGF-IR (AS[S]ODN inhibió el crecimiento tumoral. El efecto antitumoral fue específico debido a su dosis-dependencia y a la falta de efecto en ratones tratados con el S[S]ODN "sentido". Los tumores obtenidos de ratones tratados con AS[S]ODN mostraron: disminución en la expresión de IGF-IR y en la fosforilación del sustrato del receptor de insulina-1, inhibición de la activación de PI-3K/Akt, p42/p44MAPK y ErbB-2, mientras que la expresión y activación del receptor de progesterona no se afectó. Es la primera demostración que el crecimiento de cáncer de mama puede ser inhibido por la administración in vivo de AS[S]ODN al IGF-IR.We addressed the effect of targeting type I insulin-like growth factor receptor (IGF-IR, with antisense strategies in in vivo growth of breast cancer cells. We used C4HD tumors from an experimental model of hormonal carcinogenesis in which medroxyprogesterone acetate induced mammary adenocarcinomas in Balb/c mice. Intratumor or systemic administration of phosphorothiolated antisense oligodeoxynucleotides (AS[S]ODN to IGF-IR mRNA resulted in a significant inhibition of C4HD tumor growth. The antitumor effect was specific since inhibition of tumor growth was dose-dependent and no effect was observed in mice treated with sense S[S]ODN. Tumors from AS[S]ODN-treated mice showed a decrease in IGF-IR expression and in insulin receptor substrate-1 tyrosine phosphorylation. Activation of PI-3K/Akt, p42/p44 MAPK and ErbB-2 was abolished in tumors treated with AS[S]ODN. Progesterone receptor expression or activity remained

  7. Rastreo del cáncer colorrectal: Conocimiento y actitud de la población Screening colorectal cancer: Perception and behavior of the population

    Directory of Open Access Journals (Sweden)

    Enrique R. Casal

    2009-02-01

    Full Text Available El rastreo de cáncer colorrectal (CCR cuenta con fuertes evidencias en su favor. Datos preliminares indican que a pesar de ello no se lleva a cabo con la frecuencia adecuada. Se intenta aquí determinar, dentro de un Sistema de Salud que cuenta con los recursos necesarios, los elementos que facilitan o generan barreras para concretar esta práctica preventiva, cuántos individuos lo ponen en práctica y qué predice esta conducta. Se realizó una encuesta telefónica a los afiliados de una Obra Social de empleados de la Universidad de Buenos Aires, de los que 132 completaron el cuestionario (tasa de respuesta 70%. Los elementos considerados facilitadores del rastreo obtuvieron respuestas afirmativas en el 64 a 97%, mientras que los que definían barreras un 11 a 27%. En este último grupo, una categoría diferenciada la constituía el miedo a los efectos adversos: 39%, y el sentimiento de vergüenza relacionado con los procedimientos: 30%. Un 33% de los encuestados tenían hecho un método de rastreo, mayoritariamente de sangre oculta (27, sigmoideoscopía (11 y colonoscopía (20. Una mayoría afirmó que "se haría el procedimiento si el médico se lo recomendara" (95%, o "no se lo haría excepto que su médico se lo aconseje" (87%. Contestar afirmativamente que "los médicos hacen lo mejor para los pacientes" se asoció con haberse hecho un método de rastreo de CCR, OR 1.55 (IC 95%: 1.02-2.37 p: 0.04. El grupo de individuos estudiado parece bien predispuesto para el rastreo del CCR, la recomendación médica sería aquí un determinante prominente para ponerlo en práctica.There is strong evidence favoring colorectal cancer screening. Preliminary data suggests that it is not included in routine practice with the adequate frequency. We intended to recognize in a Health Care System (HCS that provides the needed resources, the facilitators and barriers related with the implementation of this preventive practice, how many individuals have

  8. Liquen plano en el Programa de Detección Precoz del Cáncer Bucal Lichen planus in the Program for the Early Detection of Oral Cancer

    Directory of Open Access Journals (Sweden)

    Pedro A. Ducasse Olivera

    2005-12-01

    Full Text Available El liquen plano es una enfermedad dermatológica de origen desconocido que se manifiesta en la mucosa bucal. Se realizó un estudio retrospectivo con los pacientes pesquisados mediante el Programa de Detección Precoz del Cáncer Bucal en el municipio especial Isla de la Juventud, con el objetivo de determinar el comportamiento epidemiológico de esta entidad, distribución según sexo, raza y zona bucal mas afectada, así como establecer la relación entre la aparición de las lesiones en piel y mucosas. Según los resultados, se determinó que el liquen plano oral es más común en hombres de la tercera y sexta décadas, principalmente en mestizos y blancos, la zona más afectada fue el carrillo (42.9 % y las lesiones cutáneas aparecieron solo en 2 casos (9.5 %.Lichen planus is a dermatological disease of unknown origin that manifests itself in the oral mucosa, reason for which we decided to conduct a study on it as part of the Program for the Early Detection of Oral Cancer in the Isle of Youth special municipality with the patients screened in this program aimed at determining the epidemiological behavior of this entity, distribution by sex, race, the most affected oral zone, and the relation between the appearance of injuries in the skin and mucosas. According to the results, it was concluded that the oral lichen planus is more comon in men at the third and sixth decades of life, in mestizoes and white individuals, and that the cheek was the most affected area. The cutaneous lesions appeared only in 2 of the 21 affected cases.

  9. US - Former Soviet Union environmental management activities

    International Nuclear Information System (INIS)

    1995-09-01

    The Office of Environmental Management (EM) has been delegated the responsibility for US DOE's cleanup of nuclear weapons complex. The nature and the magnitude of the waste management and environmental remediation problem requires the identification of technologies and scientific expertise from domestic and foreign sources. This booklet makes comparisons and describes coordinated projects and workshops between the USA and the former Soviet Union

  10. 76 FR 10209 - Corporate Credit Unions

    Science.gov (United States)

    2011-02-24

    ...(a)(4). Section III--Economic Advisability; Subsection B--Proposed Management's Character and Fitness... ``competence, experience, character, or integrity.'' The commenter suggested that these criteria should be the... any credit union depends on: (a) The character and fitness of management; (b) the depth of the members...

  11. A virtual capital for the European Union?

    NARCIS (Netherlands)

    Mamadouh, V.

    2000-01-01

    This article explores the websites of the key institutions of the European Union to consider whether these applications of the new information and communication technologies may become a functional equivalent of the national capital city in the emerging supranational political arena. Three functions

  12. Union Contracts and Teacher Professional Development

    Directory of Open Access Journals (Sweden)

    Paul V. Bredeson

    2001-07-01

    Full Text Available In this article, I report the results of an investigation that examined the impact of teacher union contracts on the development of professional learning communities in schools. There are three primary sources of data used in the study: 1 100 written teacher union contract documents; 2 structured interview data from 21 educators (school superintendents, principals, directors of staff development, and teacher union representatives; and 3 focus group interview data from educational leaders in schools. The analysis and discussion focus on five areas related to teacher professional development with implications for policy and practice: explicit language covering opportunities for teaching learning in their work; governance and decision making structures, that is, specific provisions covering wages, hours, and conditions of employment; the description of legitimate and sponsored activities for the professional development of teachers; and the resources supporting the on-going professional growth of teachers. The findings indicate that rethinking, restructuring, and organizational re-culturing in schools are initial expressions of a new unionism that has the potential to lead to the development of more powerful professional learning communities in schools.

  13. Complexity in union-free regular languages

    Czech Academy of Sciences Publication Activity Database

    Jirásková, G.; Masopust, Tomáš

    2011-01-01

    Roč. 22, č. 7 (2011), s. 1639-1653 ISSN 0129-0541 Institutional research plan: CEZ:AV0Z10190503 Keywords : Union-free regular language * one-cycle-free-path automaton * descriptional complexity Subject RIV: BA - General Mathematics Impact factor: 0.379, year: 2011 http://www.worldscinet.com/ijfcs/22/2207/S0129054111008933.html

  14. The European Union: a strategic approach

    Directory of Open Access Journals (Sweden)

    Lieve Fransen

    2007-01-01

    Full Text Available The European Union has developed policies and instruments that address – both directly and indirectly – sexual violence in conflict and beyond. Policy areas that are important in this respect include human rights, gender equality, development cooperation, humanitarian aid and conflict prevention.

  15. JPRS Report, Soviet Union, Political Affairs

    Science.gov (United States)

    1989-12-07

    in charge of policy on nationality, on the creation of a special department of the CPSU Central Committee, staffed by representatives of union...the situation on the level of the political behavior and attitudes of conflicting groups and, second, the academics’ own ethnocentric attitudes

  16. 75 FR 60651 - Corporate Credit Unions

    Science.gov (United States)

    2010-10-01

    ...) setting forth the requirements and process for chartering corporate federal credit unions. DATES: Comments... commitment (i.e., letters and/or contracts used to substantiate projections); and Services and marketing... assurance that the management team will have the requisite skills--particularly in leadership, accounting...

  17. 76 FR 54991 - Corporate Credit Unions

    Science.gov (United States)

    2011-09-06

    ... believes the credit risk of carrying this asset is negligible and warrants such treatment, as CLF stock is... credit union excludes the consolidated assets of such programs from risk-weighted assets pursuant to... paragraphs (c)(3) and (f)(4) and adding new p(h) to read as follows: Sec. 704.6 Credit risk management...

  18. Union Listing via OCLC's Serials Control Subsystem.

    Science.gov (United States)

    O'Malley, Terrence J.

    1984-01-01

    Describes library use of Conversion of Serials Project's (CONSER) online national machine-readable database for serials to create online union lists of serials via OCLC's Serial Control Subsystem. Problems in selection of appropriate, accurate, and authenticated records and prospects for the future are discussed. Twenty sources and sample records…

  19. Biomass energy: progress in the European Union

    Energy Technology Data Exchange (ETDEWEB)

    Coombs, J. [CPL Scientific Limited, Newbury (United Kingdom)

    1996-05-01

    A brief overview of the progress in the use of biomass energy in the European Union is presented. Wood fuel, support for renewable energy research, liquid biofuel, wastes and residues, and non-food use of crops such as the production of fuels from lignocellulosic materials are examined. (UK)

  20. 32 CFR 643.116 - Credit unions.

    Science.gov (United States)

    2010-07-01

    ... buildings, without charge for rent or services, to any credit union organized under State law or to any... that, in either case, that 95 percent of the membership is composed of Federal employees, including former Federal employees who acquire membership while employed by the Federal Government and retained...

  1. 75 FR 73000 - Corporate Credit Unions

    Science.gov (United States)

    2010-11-29

    ... correcting adjustments necessary to conform with generally accepted accounting principles (GAAP) that were... report, signed by the chief executive officer and the chief accounting officer or chief financial officer... either the chief accounting officer or chief financial officer of the corporate credit union to sign the...

  2. ANALYSIS OF EUROPEAN UNION LEGISLATION ON TRADE

    Directory of Open Access Journals (Sweden)

    GRIBINCEA Lilia;

    2016-12-01

    Full Text Available On June 27, 2014 there was signed an Association Agreement between the Republic of Moldova, on one hand and the European Union and the European Atomic Energy Community and its Member States, on the other hand (hereinafter - the Association Agreement. The Association Agreement entered into force on 1 July 2016. The signing of the Association Agreement was as a result of the close ties between the parties established by the Partnership and Cooperation Agreement between the European Communities and their Member States, on the one hand, and the Republic of Moldova on the other hand, which develops within the European Neighborhood policy and the Eastern Partnership, as well as recognition of the shared desire of the parties to further develop, strengthen and expand their relationships. The Association Agreement contributes to the development of trade and economic relations between the parties. The Republic of Moldova is obliged to take necessary measures to ensure compliance with the objectives of Union's regulations and to follow the principles and practices set out in the relevant acquis of the Union. The Republic of Moldova will also gradually include relevant acquis of the Union in its legislation, in accordance with the provisions of the Association Agreement. The legislative background regulatory EU trade is subject studies only a small circle of researchers, approaches and sequential episodic in character, without being integrated into a systemic study, complex, integrated. The objectives of the research are to analyze the most important EU regulations on trade.

  3. Graft union formation in Douglas-fir.

    Science.gov (United States)

    D.L. Copes

    1969-01-01

    Greenhouse-grown Douglas-fir (Pseudotsuga menziesii [Mirb.] Franco) graft unions were examined between 2 and 84 days after grafting. Room temperature was maintained at 60-70 F throughout the growing season. In most respects grafts of Douglas-fir followed development patterns previously reported for spruce and pine grafts, but specific differences...

  4. European Union Financial Crisis: A Marxist Analysis

    NARCIS (Netherlands)

    Petrus Kanisius Farneubun, P.

    European financial crisis poses a serious challenge to the fundamental structure of the European Union, political and financial institutions, as well as the values that bind European together. Different factors have been suggested as the causes of the crisis notably the failure of national

  5. Trade Union Participation in University Research Policies.

    Science.gov (United States)

    Leydesdorff, Loet

    1984-01-01

    The recent development of Dutch research coordination agencies, the Science Shops, forms the context for a description of the relationship between university research and policy at Amsterdam University and the national trade union organization. Management tools such as project financing and other elements of this system are discussed. (MSE)

  6. Union Gas Ltd. : 1998 annual report

    International Nuclear Information System (INIS)

    1999-01-01

    Consolidated annual financial information from Union Gas Ltd. was presented along with a review of their 1998 operations. On January 1, 1998, Union Gas Ltd. amalgamated with Centra Gas Ontario Inc. Both are wholly-owned subsidiaries of Westcoast Energy Inc., and had operated under a shared services arrangement since 1994. The assets, liabilities and shareholders equity of Union and Centra were combined and accounted for at their carrying amounts. In 1998, the customer base grew by 3.3 per cent. The distribution service area of Union Gas extends across northern Ontario from the Manitoba border to the North Bay/Muskoka area and through certain parts of southern Ontario. The company also provides natural gas storage and transportation services for other utilities and energy market participants in Ontario, Quebec and the United States. This report gives full account of the company's energy resource activities, presents a detailed operations review as well as the company's consolidated financial statements. Revenue for 1998 was $1.6 billion, net income was 109 million, and assets were $4 billion. Total throughput for 1998 was 31.8 billion cubic metres of natural gas. tabs., figs

  7. The demographic situation in the European Union

    NARCIS (Netherlands)

    van Nimwegen, N.; van der Erf, R.F.; Heering, E.L.; van Nimwegen, N.; van der Erf, R.

    2009-01-01

    This chapter focuses on the recent demographic situation and related population trends in the 27 Member States of the European Union. Some attention will also be paid to its two Candidate Countries, Croatia and the Former Yugoslav Republic of Macedonia, as well as to the EFTA Countries (Iceland,

  8. Sustainability Begets Unsustainability?: The European Union's Drive ...

    African Journals Online (AJOL)

    The mandatory target for the European Union (EU) for the use of renewable energy in transport by the year 2020 has created a situation where the African continent has witnessed a number of European agricultural firms gaining access to large tracts of land in order to grow crops for the production of agrofuels. This article ...

  9. Trade Unionism, Collective Bargaining and Nation Building

    African Journals Online (AJOL)

    Dr Ike

    This paper tends to examine the impact of trade unionism .... NLC waxed very strong despite the incessant harassments, detention and intimidation on the ..... effect the decisions of such agreements in a negative way as could be seen in many ...

  10. Road safety policy of the European Union.

    NARCIS (Netherlands)

    2013-01-01

    The European Union (EU) is important for national road safety policies. The EU has several policymaking instruments, such as binding regulations and directives, and non-binding recommendations. An important element in the EU policy plans on road safety are the non-binding European road safety

  11. Multiple inequalities, intersectionality and the European Union

    NARCIS (Netherlands)

    Verloo, M.M.T.

    2006-01-01

    The European Union (EU), a pioneer in gender equality policies, is moving from predominantly attending to gender inequality, towards policies that address multiple inequalities. This article argues that there are tendencies at EU level to assume an unquestioned similarity of inequalities, to fail to

  12. 75 FR 75648 - Corporate Credit Unions

    Science.gov (United States)

    2010-12-06

    ... Board, National Credit Union Administration, 1775 Duke Street, Alexandria, Virginia 22314- 3428. Hand... library at 1775 Duke Street, Alexandria, Virginia 22314, by appointment weekdays between 9 a.m. and 3 p.m... Attorney, Office of General Counsel; and Lisa Henderson, Staff Attorney, Office of General Counsel, at the...

  13. Teachers Unions and the Common Core

    Science.gov (United States)

    Russo, Alexander

    2015-01-01

    The media and observers across the ideological spectrum were surprised and, in some cases, disconcerted in July 2014, when at the annual American Federation of Teachers (AFT) convention in Los Angeles, the union's leadership team announced that its Innovation Fund grants of $20,000 to $30,000 were going to be made available to state and local…

  14. Teachers' Unions Take Own Path on Election

    Science.gov (United States)

    Hoff, David J.

    2008-01-01

    This article reports on two national teachers' unions' different approaches to the 2008 U.S. election campaign. The National Education Association is ready to spend $40 million this election year, but it is not ready to endorse a candidate for president. The American Federation Teachers, by contrast, is working aggressively for U.S. Sen. Hillary…

  15. Complexity in union-free regular languages

    Czech Academy of Sciences Publication Activity Database

    Jirásková, G.; Masopust, Tomáš

    2011-01-01

    Roč. 22, č. 7 (2011), s. 1639-1653 ISSN 0129-0541 Institutional research plan: CEZ:AV0Z10190503 Keywords : Union-free regular language * one-cycle-free- path automaton * descriptional complexity Subject RIV: BA - General Mathematics Impact factor: 0.379, year: 2011 http://www.worldscinet.com/ijfcs/22/2207/S0129054111008933.html

  16. JPRS Report. Soviet Union: International Affairs

    Science.gov (United States)

    1988-03-18

    peoples. Kkhir Dzhokhari states that the recent success- ful visit of Malaysian Prime Minister Mahathir bin Mohamad to the Soviet Union, which here...university. In his speeches during his stay in the USSR in July and August of this year, Prime Minister Mahathir bin Moha- mad, emphasizing the "coincidence

  17. "Cancer tumor".

    Science.gov (United States)

    Bronshtehn, V. A.

    The title is a phrase borrowed from a speech by a Leningrad pressman, V. E. Lvov, who called upon those attending a theoretical conference on ideological issues in astronomy held by the Leningrad Branch of the All-Union Astronomic and Geodetic Society (13 - 4 December 1948), "to make a more radical emphasis on the negative role of relativistic cosmology which is a cancer tumor disintegrating the contemporary astronomy theory, and a major ideological enemy of a materialist astronomy".

  18. LABOUR TAXATION IN THE EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    Sabau-Popa Liviu Mihai

    2011-07-01

    Full Text Available This article proposes an analysis, which we consider extremely useful in the current economic context, of the evolution of labour income fiscality, more precisely, the effect of the public debt growth on the tax wedge for the labour income. The share of fiscal revenues from direct taxes, indirect taxes and social contributions is relatively close in the old member states of the European Union in comparison with the new member states, which register a lower level of income from direct taxes. The low level of income from direct taxes is compensated by more significant shares of the social contributions or indirect taxes. The main motivations of cross-border migration are: a successful career in a multinational corporation, high variations of the tax rate, of the salary income between states and, last but not least, the level of the net salary. To this day, there are no plans to harmonize across the European Union the legislation regarding the taxes wages and the social security contributions. Still, the European Union had in view the coordination of the national tax systems to make sure that the employees and the employers do not pay several times the social contributions in their movement across the community space. Despite the fact that some states tax the labour income at a low level, the labour fiscality remains high in the European Union in comparison with other industrialized economies, probably also due to the fact that the majority of the member states have social market economies. The increase of the fiscality level for the labour income determines the decrease of the employment rate and the raise of the unemployement rate. The solution to guarantee a higher employment rate, which is a target of the European Union Strategy Europe 2020 could be the relaxation of the labour income fiscality by transferring the tax wedge on the labour income towards property or energy taxation.

  19. High frequency of the recurrent c.1310_1313delAAGA BRCA2 mutation in the North-East of Morocco and implication for hereditary breast-ovarian cancer prevention and control.

    Science.gov (United States)

    Laarabi, Fatima-Zahra; Ratbi, Ilham; Elalaoui, Siham Chafai; Mezzouar, Loubna; Doubaj, Yassamine; Bouguenouch, Laila; Ouldim, Karim; Benjaafar, Noureddine; Sefiani, Abdelaziz

    2017-06-02

    To date, a limited number of BRCA1/2 germline mutations have been reported in hereditary breast and/or ovarian cancer in the Moroccan population. Less than 20 different mutations of these two genes have been identified in Moroccan patients, and recently we reported a further BRCA2 mutation (c.1310_1313delAAGA; p.Lys437IlefsX22) in three unrelated patients, all from the North-East of the country. We aimed in this study to evaluate the frequency and geographic distribution of this BRCA2 frameshift mutation, in order to access its use as the first-line BRCA genetic testing strategy for Moroccan patients. We enrolled in this study 122 patients from different regions of Morocco, with suggestive inherited predisposition to breast and ovarian cancers. All subjects gave written informed consent to BRCA1/2 genetic testing. According to available resources of our lab and enrolled families, 51 patients were analyzed by the conventional individual exon-by-exon Sanger sequencing, 23 patients were able to benefit from a BRCA next generation sequencing and a target screening for exon 10 of BRCA2 gene was performed in 48 patients. Overall, and among the 122 patients analyzed for at least the exon 10 of the BRCA2 gene, the c.1310_1313delAAGA frameshift mutation was found in 14 patients. Genealogic investigation revealed that all carriers of this mutation shared the same geographic origin and were descendants of the North-East of Morocco. In this study, we highlighted that c.1310_1313delAAGA mutation of BRCA2 gene is recurrent with high frequency in patients from the North-East region of Morocco. Therefore, we propose to use, in public health strategies, the detection of this mutation as the first-line screening tests in patients with breast and ovarian cancer originated from this region.

  20. Factores pronósticos relacionados con la supervivencia del cáncer de mama Prognostic factors related to breast cancer survival

    Directory of Open Access Journals (Sweden)

    Lourdes Flores-Luna

    2008-04-01

    Full Text Available OBJETIVO: Evaluar los factores pronósticos del cáncer de mama en mujeres mexicanas. MATERIAL Y MÉTODOS: Se incluyó a 432 mujeres con cáncer de mama admitidas de 1990 a 1999 en el Hospital General de México para evaluar la supervivencia mediante las técnicas de Kaplan-Meier y los métodos de riesgos proporcionales de Cox. RESULTADOS: La supervivencia global a cinco años fue de 58.9%. La menor supervivencia corresponde a los estadios clínicos IIIB (47.5%, IIIA (44.2% y IV(15%, la metástasis hematógena fue de 21.4% y el tumor positivo en bordes quirúrgicos de 12.5%. La invasión linfovascular (RR= 1.9; IC95% 1.3-2.8, el estadio clínico IV (RR= 14.8; IC95% 5.5-39.7 y el tumor en bordes quirúrgicos (RR= 2.4; IC95% 1.2-4.8 fueron los principales factores pronósticos. CONCLUSIONES: Estos resultados dan consistencia a los criterios de diagnóstico y tratamiento de las mujeres con cáncer de mama atendidas en México y toman en consideración las condiciones de la tumoración, como extensión de la malformación, etapa clínica y estado de los ganglios linfáticos antes de decidir la conducta terapéutica inicial.OBJECTIVE: To evaluate prognostic factors for breast cancer in Mexican women. MATERIAL AND METHODS: Four hundred and thirty two women with breast cancer, admitted from 1990 to 1999 to the General Hospital of Mexico, were included to evaluate their survival using the Kaplan-Meier technique and Cox proportional hazard method. RESULTS: Overall 5-year survival was 58.9%. The shortest survival rate corresponds to the clinical stage (IIIB, 47.5%; IIIA, 44.2%; and IV, 15%, the haematological metastasis (21.4% and surgical edges with positive tumor (12.5%. Lymph node-positive (RR, 1.9; IC95%, 1.3-2.8, clinical stage IV (RR, 14.8; IC95%, 5.5-39.7 and surgical edges with positive tumor (RR, 2.4; IC95%, 1.2-4.8 were the central prognostic factors. CONCLUSIONS: These results give consistency to diagnostic and therapeutic criteria for women

  1. Former Soviet Union Hydrological Snow Surveys, 1966-1996

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Former Soviet Union Hydrological Snow Surveys are based on observations made by personnel at 1,345 sites throughout the Former Soviet Union between 1966 and...

  2. Slaves, Contrabands, and Freedmen: Union Policy in the Civil War

    National Research Council Canada - National Science Library

    Howard, Michelle

    1998-01-01

    This study examines Union slave policy in the Civil War. Prior to the initiation of hostilities, President Abraham Lincoln stated that the conflict between the states was over the preservation of the Union, and not over slavery...

  3. Applications of Soft Union Sets in the Ring Theory

    Directory of Open Access Journals (Sweden)

    Yongwei Yang

    2013-01-01

    through discussing quotient soft subsets, an approach for constructing quotient soft union rings is made. Finally, isomorphism theorems of λ,μ-soft union rings related to invariant soft sets are discussed.

  4. Training volume and injury incidence in a professional rugby union ...

    African Journals Online (AJOL)

    The multiplicity of factors that contribute to injury in rugby union makes it difficult to .... computed under the assumption that rugby union matches last on average 80 ..... for the physiological and musculoskeletal demands of competition. 20.

  5. Slaves, Contrabands, and Freedmen: Union Policy in the Civil War

    National Research Council Canada - National Science Library

    Howard, Michelle

    1998-01-01

    This study examines Union slave policy in the Civil War. Prior to the initiation of hostilities, President Abraham Lincoln stated that the conflict between the states was over the preservation of the Union, and not over...

  6. BUILDING A BANKING UNION IN THE EUROPEAN UNION – A SOLUTION TO THE FINANCIAL CRISIS?

    Directory of Open Access Journals (Sweden)

    Monica (ŞAGUNA FIGHIROAE

    2015-07-01

    Full Text Available The financial crisis of 2008 highlighted the need for a deeper integration of the banking system, as a warranty to support long-term financial stability. It was argued that the grounds of the crisis lie also in an uncoordinated national response to the failure of banks, in a fragmentation of the Single Market in lending and funding and, therefore, a better regulation and supervision of the financial sector can ensure financial stability and growth in the European Union. In order to restore the proper functioning of the internal market and to avoid future crisis, the European Commission launched a set of initiatives, in order to assure a safer and sounder financial sector for the single market; are included here: stronger prudential requirements for banks, improved depositor protection and rules for managing failing banks and a single rulebook for all the 28 Member States of the European Union. The single rule book is the step towards the Banking Union sits. The banking union consists of three pillars: a Single Supervisory Mechanism, a Single Resolution Mechanism and a joint deposit-insurance scheme. As on 4 November 2014 the European Central Bank assumed responsibility for euro area banking supervision, the Banking Union is still under construction. In this framework, the purpose of my paper is to analyse the process of building a Banking Union in Europe. Therefore, the objectives of my paper are to explore the steps to fulfilling a real integration of the European banking system, as a solution to the financial crisis.

  7. Union Free-Riding in Britain and New Zealand

    OpenAIRE

    Alex Bryson

    2006-01-01

    The percentage of workers who choose not to join the union available to them at their workplace has been rising in Britain and New Zealand. Social custom, union instrumentality, the fixed costs of joining, employee perceptions of management attitudes to unionization and employee problems at work all influence the propensity to free-ride. Ideological convictions regarding the role of unions also play some role, as do private excludable goods. There is little indication of employer-inspired pol...

  8. Education for the Rights and Responsibilities of Trade Union Membership.

    Science.gov (United States)

    World Confederation of Organizations of the Teaching Profession, Morges (Switzerland).

    It is vitally important for workers in all regions of the world to form unions and to exercise the rights and discharge the responsibilities which membership involves. The right to organize or join a union is essential not only for the welfare of the individual worker, or for all of those belonging to the union, but also for the welfare of society…

  9. European Union Legal Methods - Moving Away From Integration

    NARCIS (Netherlands)

    Eckes, C.; Neergaard, U.; Nielsen, R.

    2013-01-01

    Notwithstanding the permanent state of crises of the European Union (EU or Union) in the past seven years, EU law continues to govern the legal relationships of individuals and Member States in ever more areas. Union law is self-reinforcing in the sense that it is constructed to increase in scope

  10. The Role of Unions in the American Economy. Second Edition.

    Science.gov (United States)

    Marshall, Ray; Rungeling, Brian

    Intended as a resource for secondary teachers, this book analyzes the role of unions in the American economy and examines the main forces influencing unions in the United States. This second edition includes important domestic and external events that have affected U.S. economic policy and unions since the first edition was published in 1976.…

  11. Unionization, Spill-Over Effects, and Corporate Policies

    DEFF Research Database (Denmark)

    Florysiak, David

    2017-01-01

    Labor unions influence firm decisions depending on how powerful they are. We develop a new measure of union power faced by individual firms. Our measure is based on annual 10-K filings and reflects the amount of union and labor related discourse in the narrative parts of the annual report. Thus, ...

  12. 76 FR 16235 - Corporate Credit Unions, Technical Corrections

    Science.gov (United States)

    2011-03-23

    ... inadvertently included particular investments that did not--when subject to the other credit risk and asset... NATIONAL CREDIT UNION ADMINISTRATION 12 CFR Part 707 RIN 3133-AD58 Corporate Credit Unions, Technical Corrections AGENCY: National Credit Union Administration (NCUA). ACTION: Final rule. SUMMARY: In...

  13. New "Right to Work" Laws Could Hobble Faculty Unions

    Science.gov (United States)

    Schmidt, Peter

    2013-01-01

    Faculty unions outside Michigan have reason to be concerned with its passage of legislation barring unions from collecting fees from workers who do not join them. But the experiences of faculty unions in states that adopted such laws years ago suggest that while the measures can be a major hindrance to their work, they are not a death blow.…

  14. Potencial del Agua del suelo

    Directory of Open Access Journals (Sweden)

    Bustamante Heliodoro

    1986-12-01

    Full Text Available La energía potencial del agua presenta diferencias de un punto del suelo a otro; esas diferencias son las que originan el movimiento del agua de acuerdo a la tendencia universal de la materia en el sentido de moverse de donde la energía potencial es mayor a donde dicha energía es menor. En el suelo el agua en consecuencia se mueve hacia donde su energía decrece hasta lograr su estado de equilibrio. Se desprende entonces que la cantidad de energía potencial absoluta contenida en el agua, no es importante por sí misma, sino por su relación con la energía en diferentes lugares dentro del suelo. El concepto Potencial de agua del suelo es un criterio para esta energía.

  15. La traduccion del conocimiento en cancer cervicouterino: una brecha entre la investigacion sobre las causas y la investigacion sobre la atencion al paciente?

    Directory of Open Access Journals (Sweden)

    David Fajardo-Ortiz

    2014-02-01

    Full Text Available En este trabajo construimos un mapa de la traducción del conocimiento sobre cáncer cervicouterino, basado en el análisis de redes de citación y en el uso de términos del “Gene Ontology” y del Medical Heading Subject. Identificamos dos campos de investigación sobre cáncer cervicouterino, pobremente conectados entre sí, que difieren en estructura, contenido y evolución. Un área esta centrada en el estudio de las causas de la enfermedad, mientras que la otra se centra en la atención al paciente. En la primera área encontramos un proceso de traducción del conocimiento en la que la investigación clínica y la investigación básica se comunican a través de un conjunto de artículos que consolidan la infección por el papilomavirus como la causa necesaria del cáncer cervicouterino. La primera área está orientada a prevenir la infección por el virus del papiloma humano y el subsecuente desarrollo del cáncer cervicouterino, mientras que la otra área se ocupa de la estadificación y tratamiento de la enfermedad.

  16. Health and economic impact of human papillomavirus 16 and 18 vaccination of preadolescent girls and cervical cancer screening of adult women in Peru Repercusiones sanitarias y económicas de la vacunación de niñas preadolescentes contra los tipos 16 y 18 del virus del papiloma humano y el tamizaje del cáncer cervicouterino en las mujeres adultas en el Perú

    Directory of Open Access Journals (Sweden)

    Sue J. Goldie

    2012-12-01

    Full Text Available OBJECTIVE: To estimate the benefits, cost-effectiveness (i.e., value for money, and required financial costs (e.g., affordability of adding human papillomavirus (HPV vaccination to Peru's cervical cancer screening program. METHODS: Evidence (e.g., coverage, delivery costs from an HPV vaccination demonstration project conducted in Peru was combined with epidemiological data in an empirically calibrated mathematical model to assess screening (HPV DNA testing three to five times per lifetime and HPV vaccination under different cost, coverage, and efficacy assumptions. Model outcomes included lifetime risk of cancer reduction, cancer cases averted, lives saved, average life expectancy gains, short-term financial costs, and discounted long-term economic costs. RESULTS: Status quo low levels of screening (e.g., cytologic screening at 10.0% coverage reduced lifetime risk of cervical cancer by 11.9%, compared to not screening. Adding vaccination of preadolescent girls at a coverage achieved in the demonstration program (82.0% produced an additional 46.1% reduction, and would cost less than US$ 500 per year of life saved (YLS at ~US$ 7/dose or ~US$ 1 300 at ~US$ 20/dose. One year of vaccination was estimated to cost ~US$ 5 million at ~US$ 5/dose or ~US$ 16 million at ~US$ 20/dose, including programmatic costs. Enhanced screening in adult women combined with preadolescent vaccination had incremental cost-effectiveness ratios lower than Peru's 2005 per capita gross domestic product (GDP; US$ 2 852, in 2009 US$, and would be considered cost-effective. CONCLUSIONS: Preadolescent HPV vaccination, followed by enhanced HPV DNA screening in adult women, could prevent two out of three cervical cancer deaths. Several strategies would be considered "good value" for resources invested, provided vaccine prices are low. While financial costs imply substantial immediate investments, the high-value payoff should motivate creative mechanisms for financing and scale-up of

  17. Unidad en la diversidad : la convivencia de las diferencias culturales en las uniones mixtas

    OpenAIRE

    Mora Quiñones, Nidia Gloria

    2016-01-01

    Las sociedades contemporáneas cada vez más interconectadas globalmente confirman la diversidad humana en todas sus manifestaciones, siendo una de ellas la dinámica organización dentro de modalidades familiares que se constituyen en el marco de los derechos y los principios que defienden su reconocimiento y dignidad. El creciente número de uniones mixtas constituidas por las personas de diverso origen nacional, religioso y/o étnico, ha llamado la atención del ámbito científico a pesar de su ex...

  18. RENEWABLE ENERGY STRATEGIES: WHERE EUROPEAN UNION HEADED?

    Directory of Open Access Journals (Sweden)

    RADULESCU IRINA GABRIELA

    2015-06-01

    Full Text Available The states from European Union must take advantage from renewable energy sources in order to revive the economy. Climate change creates new jobs and could reduce energy imports which would stimulate the economy of those states. The European Union should support research in the field, apply more efficient policies in energy, and create economies of scale to get an integrated European energy market in which the main actors can reduce the cost of production of renewable energy. In addition, it is possible to use the comparative advantages of the Member States and not only, like Greece, through solar energy, Southern Mediterranean, through distribution networks interconnections with EU, Russia and Ukraine, through biomass and the North Sea, through wind energy. This paper refers to the evolution and trends of the renewable energy sources and presents some scenarios of it.

  19. Labour market asymmetries in a monetary union

    DEFF Research Database (Denmark)

    Seneca, Martin; Andersen, Torben M.

    This paper takes a first step in analysing how a monetary union performs in the presence of labour market asymmetries. Differences in wage flexibility, market power and country sizes are allowed for in a setting with both countryspecific and aggregate shocks. The implications of asymmetries...... is not strictly increasing in nominal rigidities but hump-shaped. Moreover, a disproportionate share of the consequences of wage inflexibility may fall on small countries. In the case of country-specific shocks, a country unambiguously benefits in terms of macroeconomic stability by becoming more flexible, while...... this is not necessarily the case for aggregate shocks. There may thus be a tension between the degree of flexibility considered optimal at the country level and at the aggregate level within the monetary union....

  20. SPECIALIZED COURTS OF THE EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    Ioana Nely Militaru

    2013-11-01

    Full Text Available Treaty of Lisbon entered into force on 1 December 2009, improved functioning judicial system European Union ( EU. Court of Justice of the EU has been reformed, said Treaty changing the EU courts so very name : Court of Justice of the EU, the Court referred to above, the Court of First Instance, and specialized courts, known previously, judicial panels. The paper shows the first part of his creation, composition and competence of the specialized courts, and as a manifestation of them in the second part examines the Civil Service Tribunal, the same point of view. EU specialized courts may be set up in specific areas, specializing in some technical disputes. These specialized courts have jurisdiction to hear and decide the cases in the first instance with the possibility that their decision subject to appeal to the General Court . In this context, to resolve disputes between the Union and its officials was established Tribunal.

  1. Intersections and Unions of Session Types

    Directory of Open Access Journals (Sweden)

    Coşku Acay

    2017-02-01

    Full Text Available Prior work has extended the deep, logical connection between the linear sequent calculus and session-typed message-passing concurrent computation with equi-recursive types and a natural notion of subtyping. In this paper, we extend this further by intersection and union types in order to express multiple behavioral properties of processes in a single type. We prove session fidelity and absence of deadlock and illustrate the expressive power of our system with some simple examples. We observe that we can represent internal and external choice by intersection and union, respectively, which was previously suggested by Padovani for a different language of session types motivated by operational rather than logical concerns.

  2. Nuclear power and European Union enlargement challenge

    International Nuclear Information System (INIS)

    Chirica, T.; Bilegan, C.; Pall, S.; Sandru, P.

    2000-01-01

    In the nuclear power sector, the main concern for the candidate countries entering the European Union, remains the nuclear safety. New standards and regulation will be issued for improving the general quality of life in a sound environment. For the candidate countries entering the European Union, this situation represents a real challenge. Their national legislation must be improved to meet the European standards. The conditions are different from country to country, and more difficult for those, which operate ''non west European reactor type''. The paper also present the actual status of the Romanian legislation related to nuclear power and environment. There are presented the principles, terms and responsibilities contained in this legislation. The authors discuss some aspects related to the possibilities to improve the national legislation to meet the actual European Commission or EURATOM standards. (author)

  3. Fear and Leadership in Union Organizing Campaigns

    Directory of Open Access Journals (Sweden)

    Caroline Murphy

    2016-01-01

    Full Text Available This article adopts a mobilization framework to examine the crucial actions of workplace activists in overcoming fear of employer reprisal during union organizing campaigns in hostile environments. The article explores fear as part of the organizing process in two ways; first, we examine how fear can act as a stimulus for workplace activists to take action in an attempt to overcome the source of that fear. Second, we examine fear as an inhibiting factor in organizing, whereby the presence of fear hinders individuals from taking action. Using qualitative data from interviews conducted with workplace activists across a variety of campaigns in Ireland, this article examines the process through which workplace activists conquer their own sense of fear and undertake the task of mobilizing colleagues toward collective action in pursuit of union representation amid fear of employer reprisal.

  4. FACTORING PERSPECTIVE: CROATIA VS EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    Zoran Ivanovic

    2012-12-01

    Full Text Available This paper points out the problems of liquidity, disposal and obtaining funds, inability to collect receivables, delayed payments in times of economic and financial instability and dynamic business upheavals and uncertainty. As a contribution to resolve these issues new alternative methods of financing for business are imposing, one of them is factoring. Although most countries don’t have adequate legal framework, factoring has emerged as the dominant form of financing, whose current status and development points to the prospects of development in the future. In terms of measures and actions which are taken to combat these issues, as well as legislation, many efforts are made at international level in European Union and in Croatia. Overview and description of the factoring development, and indications for further development are presented in relation to the world, the European Union and the Republic of Croatia. This paper also describes factoring comparison among European countries.

  5. Union Gas Limited Year 2000 progress report

    International Nuclear Information System (INIS)

    Hoey, P.

    1999-04-01

    Union Gas Ltd., a subsidiary of Westcoast Energy Inc., serves approximately 1.1 million customers in more than 400 communities in Ontario. The company has $3.6 billion worth of assets including distribution, storage and transmission facilities. This report outlines the company's Year 2000 (Y2K) preparedness efforts. The company does not see any Year 2000 challenges which would impede the flow of natural gas. Union Gas has contingency plans in place to provide business continuity in the event of any internal system failures. Currently, the following systems are 100 per cent Y2K ready: (1) gas flow and control systems, (2) information technology, (3) telecommunications systems, and (4) the billing system. The remaining systems are expected to be Y2K ready by mid-1999

  6. Policy-making in the European Union

    CERN Document Server

    Pollack, Mark A; Young, Alasadair R

    2015-01-01

    Constantly evolving, and with far-reaching implications, European Union policy-making is of central importance to the politics of the European Union. From defining the processes, institutions and modes through which policy-making operates, the text moves on to situate individual policies within these modes, detail their content, and analyse how they are implemented, navigating policy in all its complexities. The first part of the text examines processes, institutions, and the theoretical and analytical underpinnings of policy-making, while the second part considers a wide range of policy areas, from economics to the environment, and security to the single market. Throughout the text, theoretical approaches sit side by side with the reality of key events in the EU, including enlargement, the ratification of the Lisbon Treaty, and the financial crisis and resulting euro area crisis, exploring what determines how policies are made and implemented. In the final part, the editors consider trends in EU policy-makin...

  7. JPRS Report, Soviet Union Economic Affairs.

    Science.gov (United States)

    1988-12-12

    that the person ordering music not only pays money, but also provides musicians with musical instruments. State orders are now backed by drums and...have become more frequent. Last year, the USSR Ministry of Light Industry organized the first Ail-Union Fashion Festival in Moscow, featuring a large...opportunities for tourism , including foreign tourism . And the influx of those who want to visit the republic is increasing sharply all the time. While foreign

  8. US - Former Soviet Union environmental management activities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    The Office of Environmental Management (EM) has been delegated the responsibility for US DOE`s cleanup of nuclear weapons complex. The nature and the magnitude of the waste management and environmental remediation problem requires the identification of technologies and scientific expertise from domestic and foreign sources. This booklet makes comparisons and describes coordinated projects and workshops between the USA and the former Soviet Union.

  9. Kazakh Initiatives on Cooperation with European Union

    Directory of Open Access Journals (Sweden)

    Rustem S. Kurmanguzhin

    2015-01-01

    Full Text Available The author of this article presents initiatives of the Republic of Kazakhstan to develop cooperation with the European Union that was initiated through 2000 - 2009. In 2000 the Republic of Kazakhstan proposed to EU Comment cooperation doctrine in Central Asia. The purpose of the doctrine lied in expanding cooperation in the areas of trade, economy and investment; in granting access to commodities and services from European markets; in developing collaboration in the areas of energy, transport, communication, finance and banking. In 2006 Kazakhstan introduced a new set of prepossess to the new European Union Strategy for Central Asian 2007-2013 that was developed under the chairmanship of Germany of the EU in the first half of 2007. The Strategy covered areas of cooperation such as regional integration, economic development, democratization, energy and security. In 2008 under the instructions of the President of Kazakhstan Ministry of Foreign Affairs in cooperation with other ministries developed a state programme "Path to Europe" for 2009 - 2011, which aided the priorities of cooperation between Kazakhstan and the European Union. "Path to Europe" has become a key initiative of the Kazakh foreign policy that was successfully implemented, as well as the most important document aimed at modernization of the national economy and the Kazakh society. In the beginning of2009 using the accumulated positive experience of cooperation with the EU and experience of a number of countries in Europe and Asia, Kazakhstan devised and submitted a concept of a new treaty which was supposed to replace the Partnership and Cooperation Agreement of 1995. The Republic of Kazakhstan's influence eventually persuaded the European Union to agree on the necessity of devising the Enhanced Partnership and Cooperation Agreement.

  10. Body Image Amongst Elite Rugby Union Players.

    Science.gov (United States)

    Gibson, Claire; Hindle, Chloe; McLay-Cooke, Rebecca; Slater, Joanne; Brown, Rachel; Smith, Brett; Baker, Dane; Healey, Philip; Black, Katherine

    2017-11-16

    There is limited information on the risk of eating disorders and body image of elite male athletes. However, research suggests there are some athletes who have poor body image and they may be at increased risk of developing eating disorders. Therefore, the current study investigated risk of eating disorders, body image, and the relationship with age, in elite rugby union players during their pre-season training period.This cross-sectional study was undertaken at the start of the pre-season amongst elite rugby union players in New Zealand. Twenty-six professional rugby union players completed a 49-item questionnaire on body image and disordered eating. A 'body image score' was calculated from questionnaire subscales including 'drive for thinness', 'bulimia' and 'body dissatisfaction', with total scores above twenty indicative of poor body image.Body image scores varied from 8-39 out of a possible 0-100. Disordered eating behaviours were reported, including binge eating at least once a week (15%, n=4/26), pathogenic weight control use (4%, n=1/26) and avoidance of certain foods (77%, n=20/26). There was a statistically significant inverse association between the bulimia subscale and age (P = 0.034).At the start of the pre-season training period, many elite rugby union players experience disturbances in body image. The prevalence of disordered eating behaviours is of concern, and needs to be minimised due to the negative impact on health and performance. A focus on assessment and education of younger male rugby players may be required in order to reduce disordered eating patterns.

  11. Excises Harmonization Stage Within the European Union

    OpenAIRE

    Drăcea, Raluca; Buziernescu, Radu

    2007-01-01

    Tax policy in the European Union consists of two components: direct taxation, which remains the sole responsibility of Member States, and indirect taxation, which affects free movement of goods and the freedom to provide services. The most important efforts for the tax harmonization were made in the domain of the indirect taxation, the consumption taxes influence the price supported by the final consumer and prevent the fiscal neutrality necessary for a fair competition on the ...

  12. GOVERNING EUROPEAN UNION TO FINANCIAL STABILITY

    Directory of Open Access Journals (Sweden)

    Ion-Lucian CATRINA

    2012-09-01

    Full Text Available In the last four years, a significant part of the European Union members has recorded a real decline in the sustainability of their public debt. The failure of Greece, Italy, Belgium or Spain to easily find funding at previous interest rates has induced the fear that the European Monetary Union would disintegrate. Such as scenario is not realistic because does not take into account the economic interdependencies that have been created between the countries participating at the monetary zone. Nevertheless, we can say that the Stability and Growth Pact which aimed towards the coordination of national fiscal policies for ensuring the stability and prudence of the budgetary climate, has failed. This failure was primarily due to the lack of specific sanctions for those members that have not fought against the fiscal imbalances and secondly to the stopping the steps forward towards a common fiscal policy. Thus, we can say that the European Monetary Union is driven now by the wrong rule of “no taxation with representation”. For these reasons, this paper aims at showing that the European fiscal federalism is still far away from becoming reality and that the new instruments chosen for the new stability of the European Monetary Union will be the task of the Member States themselves. This paper will also review the main rules that are projected to be the source for the future European financial stability and growth: the balanced budgets and the deficits built only on the “Golden Rule” premises, for which other amendments on European Treaties are expected.

  13. Synchrotron radiation sources in the Soviet Union

    International Nuclear Information System (INIS)

    Kapitza, S.P.

    1987-01-01

    Synchrotron radiation (SR) is now recognized to be an important instrument for experimental work in many fields of science. Recently the application of SR in medicine and industry, especially as a light source for microelectronics production have been demonstrated. Thus the development of SR sources has now grown to become a significant and independent dimension for accelerator research and technology. This article describes SR work in the Soviet Union

  14. Epidemiological Review of Injuries in Rugby Union

    Directory of Open Access Journals (Sweden)

    Jean-François Kaux

    2015-01-01

    Full Text Available Rugby is a sport that is growing in popularity. A contact sport par excellence, it causes a significant number of injuries. In Rugby Union, there are 30 to 91 injuries per 1000 match hours. This epidemiological review of injuries incurred by rugby players mentions the position and type of injuries, the causes, time during the match and season in which they occur and the players’ positions as well as the length of players’ absences following the injury.

  15. JPRS Report, Soviet Union, International Affairs

    Science.gov (United States)

    1989-01-05

    in the realization of a 36,000-hectare irrigation project in the Managua— Granada —Masaya region and the construction of two large workshops for the...coordinating country for the aforementioned irrigation plan in the Managua— Masaya— Granada region. Multilateral collaboration, like bilateral...international economic security corresponding to the needs of the people of the whole world is... a natural continuation of the unions’ basic demands

  16. Comportamiento clínico y epidemiológico del cáncer de cavidad oral Clinical and epidemiologic behavior of oral cancer

    Directory of Open Access Journals (Sweden)

    Alexis Peña González

    2006-04-01

    Full Text Available Se realizó un estudio descriptivo en el Hospital Oncológico Provincial Docente “María Curie” para caracterizar clínica y epidemiológicamente el cáncer de la cavidad bucal desde el año 1999 hasta el 2004. Se estudiaron 79 pacientes de un universo de 285 y se excluyeron 206 pacientes con cáncer del labio. Se analizaron las variables grupos de edades, sexo, factores de riesgo, manifestaciones clínicas, localización anatómica, tipo histológico, forma clínica, estadio clínico y modalidad terapéutica. El procesamiento estadístico se realizó mediante estadística descriptiva, tablas de contingencia y gráficos; como medida de resumen se utilizó el porcentaje y el test de proporción. Predominó la enfermedad en pacientes de 70-79 años con 24 (30,38 %, y el sexo masculino, con 59 pacientes (74,68 %. El tabaquismo se detectó en 38 de estos (48,10 %, de los cuales 35 (44,30 % refirieron dolor como principal síntoma. El carcinoma epidermoide fue la variedad histológica más frecuente (76, para el 96,20 %. Su localización prevaleció en la lengua (24 casos, para el 30,38 %. El diagnóstico frecuentemente se realizó en un estadio III (en 42 pacientes, para el 53,16 % y predominó la forma clínica mixta (38 para el 48,10 %. La radioterapia fue el tratamiento más utilizado en sus diferentes variantes con 64 casos (81,0 %.A descriptive study was conducted in “Maria Curie” Oncological Provincial Teaching Hospital in order to characterize oral cancer from the clinical and epidemiologic point of view between 1999 and 2004. 79 patients of a total of 285 were studied and 206 with lip cancer were excluded. Variables such as age groups, sex, risk factors, clinical manifestations, anatomical localization, histological type, clinical form, clinical stage and therapeutical modality were analyzed. The statistical processing was carried out by descriptive statistics, contingency tables and graphs. Percentage and proportion test were used

  17. Three proposals for revitalising the European Union

    Directory of Open Access Journals (Sweden)

    Mario Tonveronachi

    2016-12-01

    Full Text Available Widespread perception that convergence on the current set of rules is not capable of producing convergence on results, or anyway generally better results, has increased the socio-political fragmentation inside the European Union. The result has been an increasing demand for a partial re-nationalisation of sovereign powers, whose physiology comes from the necessity of higher national flexibility. Asking how feasible changes in the current set of rules could accommodate the increased demand of national flexibility, the paper focuses on the euro area and proposes to revise the monetary operations of the European Central Bank, current fiscal rules, and the financial regulatory approach. The proposed new design is based on the premise that no changes in the Treaty on the Functioning of the European Union are possible at the moment, even though a minimum political convergence is necessary. If successfully implemented, the proposal would contribute to give a viable perspective to the design of the Economic and Monetary Union, capable of attracting those EU non-euro area countries that consider the mismanagement of the recent crisis and of its after-effects reason enough for resisting further losses of sovereignty. JEL: E52, E62, F33, F36, F45, G28

  18. Union Gas Limited 2000 annual report

    International Nuclear Information System (INIS)

    2000-01-01

    Financial information from Union Gas was presented along with a review of their operations throughout 2000. Union Gas is a major Canadian natural gas utility providing energy services to more than 1.1 million residential, commercial and industrial customers in more than 400 communities in Ontario. The company also provides natural gas storage and transportation services for other utilities and energy market participants in Ontario, Quebec and the United States. Revenue for 2000 was reported to be $1.6 billion, net income was $113 million and assets totaled $3.9 billion. Total throughput for 2000 was 35.8 billion cubic meters. Union Gas is a wholly-owned subsidiary of Westcoast Energy Inc. of Vancouver, British Columbia. In 2000, progress was made toward the introduction of performance-based regulation to replace the cost of service regulation currently in use. This initiative will enable the company to provide competitively priced services to customers, allowing them, along with shareholders to benefit from efficiency enhancements and new service offerings. tabs., figs

  19. New recommendations from the United States Government on breast cancer screening Nuevas recomendaciones del Gobierno de los Estados Unidos sobre el tamizaje del cáncer de mama

    Directory of Open Access Journals (Sweden)

    2002-03-01

    Full Text Available En los últimos años ha habido grandes controversias y debates sobre la eficacia de diferentes métodos de detección del cáncer de mama. En un esfuerzo por proporcionar orientaciones más claras tanto a las mujeres como a los profesionales de la salud, un grupo de expertos reunido por el Gobierno de los Estados Unidos de América, el llamado U.S. Preventive Services Task Force (USPSTF, publicó en febrero de 2002 un informe en el que se afirma que la mamografía permite salvar vidas y que su realización debería comenzar en la quinta década de la vida de la mujer. Este grupo de expertos dice también que no hay datos suficientes para hacer recomendaciones a favor o en contra de otros dos métodos de detección: el examen clínico de la mama y la autoexploración mamaria rutinaria. El presente documento resume las recomendaciones del informe del USPSTF, así como las principales consideraciones clínicas y pruebas científicas que presentó en áreas como la exactitud y fiabilidad de las pruebas de detección, la eficacia de la detección temprana del cáncer de mama, cuándo detener el tamizaje, el intervalo de tiempo más apropiado entre las pruebas y los potenciales perjuicios del tamizaje.

  20. Free riders: the rise of alternative unionism in Denmark

    DEFF Research Database (Denmark)

    Ibsen, Flemming; Høgedahl, Laust; Scheuer, Steen

    2013-01-01

    In this article we analyse some disturbing trends in the Danish labour market: while collective bargaining coverage is still relatively high, union density has been declining and—worse than that—there has been a substantial shift away from recognised and in favour of alternative unionism....... The alternative unions are not parties to collective agreements, and they offer membership much cheaper than the recognised unions, in effect taking a free ride on the institutional supports that used to be effective only for the recognised unions. The article explains this conundrum by pointing to the political...

  1. LEGAL PERSONALITY AND POWERS OF THE EUROPEAN UNION

    OpenAIRE

    Augustin FUEREA

    2010-01-01

    Based on legal personality, EU won through Treaty of Lisbon, in accordance with the system of division of competences between the Union and the Member States as provided for in the Treaty on European Union and the Treaty on the Functioning of the European Union, competences not conferred upon the Union in the Treaties remain with the Member States. When the Treaties confer on the Union a competence shared with the Member States in a specific area, the Member States shall exercise their compet...

  2. Radiation dose to the patient and the radiologist while performing on chest computed tomography: a program of early diagnosis of lung cancer, biopsy and treatment simulation guided radiation oncologist breast cancer; Dosis de radiacion al paciente y al radiologo durante la realizacion de tomografia computarizada en torax: progrma de diagnostico precoz del cancer de pulmon, biopsia guiada y simulacion del tratamiento oncologo radioterapico del cancer de mama

    Energy Technology Data Exchange (ETDEWEB)

    Pastor Sanchis, V.; Martinez Sanchez, J. M.; Palma Copete, J. D.; Crispin Contreras, V.; Casal Zamorano, E.; Dolores Alemany, V. de los; Gonzalez Perez, V.; Gimeno Olmo, J.; Guardino de la Flor, C.

    2011-07-01

    In this paper we determine the equivalent dose received by the operator and patient lung biopsies using thermoluminescence dosimeters, are established recommendations that this dose is as low as possible. It also reviews the acquisition protocols in both CT scans in early diagnosis program cited as the acquisition of CT for treatment planning dosimetric radiation oncologist in breast cancer.

  3. O cuidado do paciente oncológico com dor crônica na ótica do enfermeiro El cuidado del paciente oncológico con dolor crónico en la visión del enfermero The care to cancer patients with chronic pain in the view of nurses

    Directory of Open Access Journals (Sweden)

    Lili Marlene Hofstätter da Silva

    2001-01-01

    Full Text Available O objetivo deste estudo foi identificar como o enfermeiro interpreta o cuidado com o paciente oncológico com dor crônica. O estudo foi desenvolvido com oito enfermeiros de uma instituição hospitalar. Os dados foram coletados por entrevistas semi-estruturadas e na análise identificamos três categorias analíticas: a avaliação da dor crônica do paciente oncológico, a importância do cuidado multidisciplinar e as dificuldades para o cuidado do paciente. Os resultados mostram que os enfermeiros têm dificuldades em desenvolver o cuidado com o paciente devido à falta de conhecimentos específicos sobre o câncer, dor crônica e sua terapêutica, como também, nas habilidades expressivas para promoverem o apoio psicológico adequado.El objetivo de este estudio fue identificar como el enfermero interpreta el cuidado para el paciente oncológico con dolor crónico. El estudio fue desarrollado con ocho enfermeros de una institución hospitalaria. Los datos fueron recolectados por entrevistas semi-estructuradas y en el análisis identificamos tres categorías analíticas: la evaluación del dolor crónico del paciente oncológico, la importancia del cuidado multidisciplinario y las dificultades para el cuidado del paciente. Los resultados muestran que los enfermeros tienen dificultades para desarrollar el cuidado con el paciente debido a la falta de conocimientos específicos con respecto al cáncer, dolor crónico y su tratamiento, como también, en las habilidades expresivas para la promoción del apoyo psicológico adecuado.This study aims to understand how nurses interpret the care given to cancer patients with chronic pain. The informers were eight nurses from a public hospital. Data were collected on the basis of semi-structured interviews and the analysis identified three analytical categories: the evaluation of patients' pain, the importance of multidisciplinary care and nurses' difficulties to care for these patients. The results show

  4. Convergence: How Nursing Unions and Magnet are Advancing Nursing.

    Science.gov (United States)

    Johnson, Joyce E; Billingsley, Molley

    2014-01-01

    Historically, unions and professional associations such as the American Nurses Association have been adversaries in the fight to represent the best interests of the nursing profession. We reviewed the literature on the evolution of nursing unions, nursing's historical unease about unions, the Magnet designation in nursing, the tensions between the unions and Magnet, the core values and commonalities they share, and the obligations of nursing as a profession. Refocusing on the advancement of our profession provides a positive pathway in which the collective efforts of nursing unions and professional initiatives such as the Magnet designation converge during these turbulent times for our profession. The single, central organizing idea of nursing-where nursing unions and Magnet converge-is the pivotal role of nurses in delivering high-quality patient care. The often-maligned dialectic between unions and Magnet has advanced and not hindered the nursing profession. © 2014 Wiley Periodicals, Inc.

  5. Variation of cervical cancer incidence in Latin America and the Caribbean Variación de la incidencia del cáncer cervicouterino en América Latina y el Caribe

    Directory of Open Access Journals (Sweden)

    Christine M. Pierce Campbell

    2012-06-01

    Full Text Available OBJECTIVE: To provide a comprehensive analysis of the descriptive epidemiology of invasive cervical cancer in Latin America and the Caribbean by analyzing quality data from the area's cancer registries, including data that were excluded from the International Agency for Research on Cancer (IARC publication, Cancer Incidence in Five Continents, Vol. IX (CI5-IX. METHODS: This was a descriptive epidemiologic study that involved 20 cancer registries, 9 of which were included by IARC in CI5-IX, and 11 of which were not. Data on invasive cervical cancers diagnosed from 1998-2002 were obtained from IARC. A cervical cancerspecific quality assessment was performed on all registries whether or not they were included in CI5-IX. Data from 14 registries met quality criteria and were analyzed. Incidence rates were calculated and compared across registries. RESULTS: A substantial variation in incidence rates existed among the registries; agestandardized rates ranged from 14.6-44.0 per 100 000 women per year. Mean cervical cancer incidence rates were 10.4% higher for registries included in CI5-IX than for those excluded; however, this difference was not significant (P = 0.541. CONCLUSIONS: This study compared cervical cancer rates from a more diverse group of Latin American and Caribbean countries than that of the CI5-IX. The heterogeneity found among registries highlights the importance of examining data from as many registries as possible when characterizing risk across a geographic area. Data from developing countries can be used to better understand cancer distribution and enable Region-specific recommendations on cancer control and prevention once data quality has been establishedOBJETIVO: Efectuar un análisis integral de las características epidemiológicas descriptivas del cáncer de cervicouterino invasor en América Latina y el Caribe mediante el análisis de datos de calidad de los registros de cáncer de la región, incluso datos que fueron

  6. del alcoholismo

    Directory of Open Access Journals (Sweden)

    Rodrigo Arias Duque

    2005-01-01

    Full Text Available Desde el punto de vista farmacológico, es importante comprender qué es el alcohol y cómo actúa en el organismo. No existe una causa simple, sino una interacción complicada de factores neuroquímicos, fisiológicos, psicológicos y sociales que originan y desarrollan esta grave enfermedad fármaco-dependiente. La acción psicofisiológica y farmacodinámica del alcohol es fundamentalmente depresiva, por la reducción de la transmisión sináptica en el sistema nervioso humano. Es un hecho conocido que el consumo excesivo de alcohol causa una disfunción aguda y crónica del cerebro, produciendo trastornos en el sistema nervioso central, presentando alteraciones en la memoria y en las funciones intelectuales como cálculo, comprensión y aprendizaje. A nivel hepático tiene lugar, en su mayoría, el metabolismo del alcohol, produciéndose un hígado graso alcohólico, aumentando el tamaño, terminando en necrosis e inflamación grave del hígado; esto se llama hepatitis alcohólica, y si se sigue consumiendo alcohol se desarrollará la cirrosis. El alcohol también ha estado relacionado con alteraciones del miocardio; se ha constatado en animales de experimentación sanos que tanto la velocidad de contracción del músculo cardiaco y su máxima tensión disminuyen en presencia del alcohol, como consecuencia, la fuerza de cada contracción y el aumento de presión en el ventrículo izquierdo son menores, perdiendo eficacia el corazón como bomba.

  7. Missed opportunities in early diagnosis of symptomatic colorectal cancer Oportunidades perdidas en el diagnóstico temprano del cáncer colorrectal sintomático

    Directory of Open Access Journals (Sweden)

    Maite Domínguez-Ayala

    2012-07-01

    Full Text Available Objective: delays in diagnosis of symptomatic colorectal cancer are a reality in our context. This study aims at identifying missed diagnostic opportunities, describing events, clinical clues and most common mistakes, and quantifying delays. Material and methods: an observational descriptive study was performed in order to review all case histories. Two experts reviewed the case histories of all the patients from the 4th Catchment Area of Asturias diagnosed with colorectal cancer in 2009. All data were analysed using bivariate and multivariate logistic regression. Results: full information on 119 patients out of 143 patients was collected. 34.45% had a clinical missed opportunity -confidence interval (CI 95%: 30.92-39.68-. Outcomes show an average of 2.41 missed opportunities and 2.61 diagnostic clinical clues per patient. The number of patients with missed opportunities was significantly higher. The total amount of co-morbidities was higher in patients with missed opportunities (2.7. This was the main determinant. The main diagnostic key was iron-deficiency anaemia (46.3%. It produced the longest delay (300 days. Not having requested diagnostic tests was the most common mistake (43.3%. Having at least one missed opportunity entailed an average delay of 235.8 days between the first visit to the office and the referral to a consultant. Conclusions: in clinical practice, missed opportunities to start a diagnostic assessment in patients with presumptive diagnosis of colorectal cancer are common. The most significant clinical clue and the one generating the longest delay is iron-deficiency anaemia. The diagnostic delay is important and is caused mainly by not identifying symptoms.Objetivo: los retrasos en el diagnóstico de cáncer colorrectal sintomático son una realidad en nuestro medio. Nos proponemos identificar los casos en los que hubo oportunidad perdida para el diagnóstico, describir las características de los episodios, las claves cl

  8. Mortality of male members of the Danish Semi-skilled Unskilled Workers' Union in 1973

    DEFF Research Database (Denmark)

    Jeune, B

    1977-01-01

    The purpose of this cross-sectional study is to evaluate contemporary age and cause specific mortalities of a large group of employed men. The population is the 228,612 male members, aged 20-64, of Denmark's largest trade union, the Semi-skilled and Unskilled Workers' Union (SID). A Standard...... Mortality Ratio (SMR) of 93.9 compared to all men in Denmark is found. However, the distribution of mortality by age does not resemble that found in many other studies, and is usually said to result from the 'healthy worker effect'. Excess mortality is found in the younger age groups, while the opposite...... is the case in the older groups, mainly because of a deficit of deaths from chronic illness. Notably higher age and cause specific SMRs are found for violent and unnatural deaths, and higher SMRs for cancer of the lungs and of lymphatic and haemopoietic tissues. Regional variations are found...

  9. The European Fiscal Union creation process

    Directory of Open Access Journals (Sweden)

    Oleksandr Sharov

    2015-06-01

    Full Text Available The paper presents evolution of the European Union fiscal system creation process as well as outlines problems in functioning thereof that have arisen during recent years and the main reforming (modification trends. The analysis is primarily focused on creation of the fiscal union within the EU. In this regard, the idea of two different groups of countries moving to the common goal at different paces is becoming ever increasingly much-talked-about in the EU. The first group comprises donor countries that adhere to all treaties and fiscal discipline, while demonstrating respective positive macroeconomic indicators. The second group implies countries of Euro-periphery, where the above processes take place along with significant complications or do not occur at all. In these countries Eurosceptic positions are also quite strong, which often leads to taking measures contrary to the jointly adopted decisions. Currently, there is no clear understanding within the EU as to which way out of the crisis should be taken. However, profound understanding of the crisis causes and active work on preparation and implementation of measures to overcome the negative effects of this crisis suggest availability of sufficiently favorable prospects for further development of the EU fiscal system (including formal creation of the Fiscal Union. Based on the conducted analysis conclusions have been made as to potential vectors of action aimed at improving EU fiscal system, while specific recommendations on actions to be taken by Ukraine have been developed (particularly, as regards budget forecasting and planning with the purpose of harmonizing Ukrainian financial institutions and mechanisms with the EU fiscal system.

  10. Towards Regional Monetary Unions through Blockchain Networks

    OpenAIRE

    Hegadekatti, Kartik

    2017-01-01

    The concept of political and economic integration has not progressed beyond the concept of a Nation-state. The primary reason is the trust deficit among citizens in a supra-national entity. We can use Blockchain systems-which are trustless networks-to resolve this issue. We can float a Regional Cryptocurrency (RCC) which can bring about a successful Regional Monetary Unions (RMU) amongst a group of nations in a transparent manner. This paper deals with the idea of realizing a monetary uni...

  11. Strong trade unions meet EEC workers

    DEFF Research Database (Denmark)

    Andersen, Søren Kaj; Hansen, Jens Arnholtz

    2008-01-01

    (EEC) workers. The argument is that migrant and, in particular, posted workers' conditions of employment often are characterised by evasions of collective agreements, whether in the form of underpayment or other violations of terms and conditions specified in the agreements. However, the trade union...... response is not straightforward: they could pursue a strategy of surveillance and control, leading to closer cooperation with public authorities (e.g., tax and immigration authorities) in order to impose sanctions and fines on employers violating existing agreements and legislation - a strategy often met...

  12. The European Union stakes on biofuels

    International Nuclear Information System (INIS)

    Laffon, M.

    2008-01-01

    The European Union has just published the environmental side of its action in the fight against climatic change. Like the third 'energy batch', these new legislative proposals are the continuation of the January 2007 communication of the commission which aimed at fixing the trends of the energy policy of the European Communities. Some measures of these last legislative proposals, in particular those treating of biofuels, are sometimes considered as too ambitious and even unrealistic. The overall proposals are waiting for the final adoption during the French presidency. (J.S.)

  13. Food and Health Inequalities in European Union

    DEFF Research Database (Denmark)

    Robertson, Aileen

    Food and Inequalities in European Union Dr. Aileen Robertson, Public Health Nutritionist at the Metropolitan University College, Copenhagen. Dr. Robertson focused on food and inequality in light of the increased prevalence of overweight and obesity in Europe. On average over 50% of Europeans...... public procurement; 3) more democratic sustainable food systems with fairer prices to producers; 4) realise that food and nutrition policies are at the heart of achieving all 17 Sustainable Development Goals and the COP21climate goals; 5) a ‘Health in All Policies’ approach applied to CAP reform...

  14. Scientific research in the Soviet Union

    International Nuclear Information System (INIS)

    Mtingwa, S.K.

    1990-01-01

    I report on the scientific aspects of my US/USSR Interacademy Exchange Visit to the Soviet Union. My research was conducted at three different institutes: the Lebedev Physical Institute in Moscow, the Leningrad Nuclear Physics Institute in Gatchina, and the Yerevan Physics Institute in Soviet Armenia. I included relevant information about the Soviet educational system, salaries of Soviet physicists, work habits and research activities at the three institutes, and the relevance of that research to work going on in the United States. 18 refs

  15. The Fiscal Framework in a Currency Union

    DEFF Research Database (Denmark)

    Hallett, Andrew Hughes; Hougaard Jensen, Svend E.

    2016-01-01

    This paper draws out lessons from the euro area (EA) that are transferable to the Eastern Caribbean Currency Union (ECCU) and other Caribbean economies with fixed exchange rates. Based on observations from both the EA and the ECCU, we present a new policy framework which is capable of imposing...... fiscal discipline, with the aim of avoiding the risk of unsustainable fiscal policies reappearing and of preventing monetary policy from being undermined by undisciplined national governments. In the ECCU case, we find that fiscal deficits are more a result of financial and trade imbalances than fiscal...

  16. Labour Force Migration Effects within European Union

    Directory of Open Access Journals (Sweden)

    Carmen Mihaela Tudorache

    2006-10-01

    Full Text Available Within the EU, there is no common policy on migration; there are common policies on certain aspects of migration. The Member States fear of migration, but their economies and societies will further need migrant workers. Labour force migration have positive, but also negative consequences for all parties involved: receiving countries, origin countries and migrant workers. Within this framework, a common approach of the migration management and the harmonization of the economic migration policies of the Member States represent already one of the most important challenges for the European Union and will be further emphasized.

  17. Federal and European Union Policy Making

    DEFF Research Database (Denmark)

    Dosenrode, Søren

    By using the policy cycle approach, this paper compares the policy-process in a number of Anglo-Saxon type federations with the policy-process in continental-European style federations from within the European Union (EU) area.  The comparison would reveal: a) distinct different styles of policy...... making in European style federations in relation with the Anglo-Saxon ones. b) that the policy-process in the EU resembles that of the European style federations, and c) the Constitutional Treaty (CT) or a possible CT-light would strengthen the federal policy-making characteristics already present...

  18. 2009 energy prices in the European Union

    International Nuclear Information System (INIS)

    2010-01-01

    In 2009, the natural gas price fell down in the European Union (EU). This drop was of about -5% (excluding taxes) as an average for companies, and of about -3% for households (including taxes). On the other hand, the electricity prices raised by 3% for companies and by 5% for households. In France, only the gas price for companies has dropped between 2008 and 2009. The electricity prices remain significantly lower than the EU average: -29% for companies and -30% for households. The gas price in France remains close to the European average but is significantly lower than the average price in the euro area. (J.S.)

  19. Internal Border Controls in the European Union

    DEFF Research Database (Denmark)

    Jørgensen, Carsten Willemoes; Sørensen, Karsten Engsig

    2012-01-01

    Recent events, involving inter alia France and Denmark, have stimulated renewed interest in the introduction of different forms of border controls at the internal borders within the European Union. These border control measures are aimed at checking either persons or goods or both. Against...... the background of these events, this article analyses the existing rules regulating controls of persons and goods, and explores how these rules may or may not stand in the way of introducing border controls at the European Union’s internal borders. These events have resulted in a call for reforms of the current...

  20. Political public relations in the European Union

    DEFF Research Database (Denmark)

    Valentini, Chiara

    2013-01-01

    This article examines the state of political public relations in the European Union by specifically focusing on reputation management and relationship management. Its arguments are based on a theoretical review of the literature of political public relations, reputation and relationship management......, and EU communication. The article suggests an in-depth examination of the nature of some of the EU’s major problems in political public relations, and contributes to a more nuanced understanding of the possibilities and limitations of applying reputation and relationship management constructs...

  1. Research Methods in European Union Studies

    DEFF Research Database (Denmark)

    Lynggaard, Kennet; Manners, Ian; Löfgren, Karl

    Research on the European Union over the past few years has been strongly implicated in the crises that currently grip Europe with a failure to ask the pertinent questions as well as a perceived weakness in the methods and evidence used by researchers providing the basis for these allegations....... This volume moves the study of EU research strategies beyond the dichotomies of the past towards a new agenda for research on Europe through a rich diversity of problem-solving based research. This new agenda acknowledges the weaknesses of the past and moves beyond them towards greater openness and awareness...

  2. Incidencia del cáncer de vejiga urinaria en un área industrializada de España Incidence of urinary bladder cancer in an industrialized area of Spain

    Directory of Open Access Journals (Sweden)

    G. Urrutia

    2002-08-01

    Full Text Available Objetivo: Determinar la incidencia del cáncer de vejiga en la comarca del Vallès Occidental (Barcelona, describir sus características histopatológicas y comparar su incidencia con la de otras áreas españolas y europeas. Método: Se incluyeron los casos nuevos de cáncer de vejiga diagnosticados entre 1992 y 1994 en el Vallès Occidental, área muy industrializada de Cataluña (España. Se ajustaron por edad las tasas de incidencia y se compararon con las de los datos publicados en los registros de otras áreas españolas y europeas. Resultados: Se identificaron 485 casos de cáncer de vejiga, el 95,5% de los cuales eran carcinomas de células transicionales. La mayoría de los tumores (75,9% eran superficiales y tenían un grado de diferenciacón I o II (62,6%. El cáncer de vejiga fue más frecuente en los varones. Las mujeres presentaron tumores de peor pronóstico y una edad media en el momento del diagnóstico significativamente superior a la de los varones (71 frente a 66 años; p = 0,03. La tasa de incidencia ajustada para los varones (52,2 casos/100.000 fue de las más altas, mientras que en las mujeres (5,4 casos/100.000 fue relativamente baja. Conclusiones: La incidencia de cáncer de vejiga en la población del Vallès Occidental se encuentra para los varones entre las más altas de Europa, y en cambio para las mujeres ocupa un lugar bajo. La elevada razón varón/mujer observada podría ser debida a que las mujeres españolas han estado menos expuestas a los factores de riesgo, o bien lo han hecho más recientemente.Aim: To identify all incident cases of bladder cancer in the county of Vallès Occidental (Spain, describe their histopathological characteristics, and make comparisons with other Spanish and European areas. Method: The study was carried out from the Corporació Parc Taulí (Sabadell. All new cases of bladder cancer in residents of the county Vallès Occidental, a highly industrialised area of Catalonia (Spain, were

  3. Current management of gastric cancer Situación actual en el tratamiento del cáncer gástrico

    Directory of Open Access Journals (Sweden)

    Antonio Viúdez-Berral

    2012-03-01

    Full Text Available Gastric cancer is a disease with high incidence and mortality in our population. The prognosis of patients with this disease is closely related to the neoplasm stage at diagnosis, including the following characteristics of the tumor: extension into the gastric wall thickness, spread to locoregional lymph nodes and the ability to generate distant metastases, as described by the TNM classification. For localized tumors characterized only by invasion of mucosa or submucosa at diagnosis, survival at 5 years is between 70 and 95% with exclusive surgical management; however, when extension into the gastric wall is higher and/or there is locoregional nodal involvement, survival decreases to 20-30% at 5 years. Currently, at high-volume centers, the extent of gastrectomy is individualized based on several parameters, which in an increasing number of cases allows a total gastrectomy with D2 lymphadenectomy and preservation of the spleen and pancreas. This improved procedure increases the chance of R0 surgery and improves the relationship between resected and affected lymph nodes, resulting in a decreased risk of the long-term locoregional recurrence. To improve these results, different therapeutic strategies combining chemotherapy or chemoradiotherapy with surgery have been tested. Previously, the Intergroup 0116 clinical trial, published in 2001, which changed clinical practice in the United States, showed that adjuvant chemoradiotherapy improved survival (from 26 to 37 months overall survival of these patients. In Europe, perioperative chemotherapy has been considered the standard treatment, since the publication of two randomized phase III trials showed an increase at 5 years survival in the group treated with chemotherapy.El cáncer gástrico es un tumor de alta incidencia y mortalidad en nuestro medio, y su pronóstico está íntimamente relacionado con la situación neoplásica al diagnóstico, que incluye su extensión en el grosor de la pared g

  4. Código Europeo Contra el Cáncer y Salud Laboral: Actuación de la Enfermería del Trabajo European Code Against Cancer and Health: Performance of Occupational Health Nursing

    Directory of Open Access Journals (Sweden)

    Jesús González Sánchez

    2012-09-01

    Full Text Available El cáncer se ha convertido en una de las principales causas de morbi-mortalidad de la sociedad actual, afectando cada vez a un mayor número de personas y a un grupo de edades mucho más amplio, incluyéndose de forma importante la edad laboral. El Código Europeo Contra el Cáncer, constituye una herramienta eficaz para el profesional de la salud laboral, teniendo aplicación dentro de las competencias específicas otorgadas al especialista en Enfermería del Trabajo, y facilitando la realización de estudios e investigaciones epidemiológicas, que permitan obtener una estrategia de actuación preventiva eficaz, ante múltiples factores de riesgo de cáncer laboral presentes en determinadas industrias, contribuyendo a una correcta vigilancia y control de la salud.Cancer has become a major cause of morbidity and mortality in today's society, affecting more and more people and an age group much broader, including a significant working age. The European Code Against Cancer, is an effective tool for occupational health professional, having application within the powers granted to a specialist in Occupational Health Nursing, facilitating studies and epidemiological research that will generate a strategy for preventive action effectively to multiple risk factors for occupational cancer present in certain industries, achieving a proper monitoring and health surveillance.

  5. Inmunoterapia del cáncer: Importancia de controlar la inmunosupresión Cancer immunotherapy: Importance of overcoming immune suppression

    OpenAIRE

    Mariana Malvicini; Guillermo Puchulo; Pablo Matar; Guillermo Mazzolini

    2010-01-01

    Es cada vez mayor la evidencia experimental y clínica de que el sistema inmunitario interviene activamente en la patogénesis y el control de la progresión tumoral. Una respuesta antitumoral efectiva depende de la correcta interacción de varios componentes del sistema inmunitario, como las células presentadoras de antígeno y diferentes sub-poblaciones de linfocitos T. Sin embargo, los tumores malignos desarrollan numerosos mecanismos para evadir el reconocimiento y su eliminación por parte del...

  6. Union Security Provisions, Academic Freedom and Tenure: The Implications of Chicago Teachers Union v. Hudson.

    Science.gov (United States)

    Olswang, Steven G.

    1988-01-01

    The relationship between faculty union mandatory membership provisions in a collective bargaining agreement and the rights of faculty protected by tenure and academic freedom are examined, and college options and considerations in negotiating contracts under collective bargaining laws are discussed. (MSE)

  7. Where the European Union should Multiply its Money: Stimulating Measures in the Economic Monetary Union

    NARCIS (Netherlands)

    Groeneveld, A.N.; Heijman, W.J.M.

    2014-01-01

    The aim of this article is to investigate in which sectors and countries the European Union should invest to diminish the economic gap between different member states. It answers the question at which sectors and regions the European regional policy should be directed. In an attempt to indicate

  8. 78 FR 4875 - Office of Small Credit Unions (OSCUI) Loan Program Access for Credit Unions

    Science.gov (United States)

    2013-01-23

    ... credit union's marketing strategy to reach members and the community; and include financial projections... required to obtain matching funds. However, each Applicant should address in the Application its strategy...) Matching Funds: A narrative describing its strategy for raising matching funds from non-federal sources if...

  9. 78 FR 2449 - Office of Small Credit Unions (OSCUI) Grant Program Access for Credit Unions

    Science.gov (United States)

    2013-01-11

    ... members to stimulate economic activities in their communities. Through the OSCUI Grant Program, NCUA... March, 15, 2013 OSCUI will accept applications from credit unions under the Collaboration Initiative..., scalable, replicable and cost-saving collaboration. Under this initiative a single LICU must collaborate...

  10. The last-chance Union: three questions for three observations on the union of energy

    International Nuclear Information System (INIS)

    Maisonneuve, Cecile

    2016-01-01

    As the status of the European policy on energy, and of Europe itself, and even the nature of the project of a Union of energy are either in bad shape or put into question again by numerous uncertainties, as Europe is exhausted by a financial crisis, an economic crisis, a debt crisis, the Greek crisis, the Ukrainian crisis, and the refugee crisis, the author examines whether the Union of energy raises the right questions and addresses in the right way the issue of energy, whether Europe possesses the adequate political ecosystem to succeed, whether Europe is mature enough to build up a union on energy. To shed some light on these issues, the author examine the three dimensions of the union of energy: the strategic, political and economic dimensions. She analyses evolutions introduced with respect to the previous period, and assesses the relevance, impact and feasibility of announced proposals. The strategic dimension concerns the connection of Europe to the World (how to face and cope with international energetic realities, and with the current geopolitical turmoils). The politic dimension is to be found in the way to create a common impetus again, and the economic dimension deals with giving back confidence

  11. A decade of African Union and European Union trans-national ...

    African Journals Online (AJOL)

    The first decade of the new millennium saw the European Union deploy nine security missions to the African continent, quoting the European Security and. Defence Policy. Unlike the numerous United Nations security missions that. European states had previously contributed to, these were part of a grand strategy designed ...

  12. State of the Union Address, 1997. Remarks by the President in State of the Union Address.

    Science.gov (United States)

    Executive Office of the President, Washington, DC.

    This document contains the text of President Clinton's State of the Union Address, delivered on February 4, 1997. The President issues a call to action to work together to prepare America for the twenty-first century. The United States must attend to the unfinished business of balancing the budget, enacting bipartisan campaign-finance reform, and…

  13. 78 FR 33445 - Office of Small Credit Unions (OSCUI) Grant Program Access For Credit Unions

    Science.gov (United States)

    2013-06-04

    ... hardware and software necessary to convert to computerized operations. The maximum award amount for this...,000 per credit union for financial education projects that improve financial capability in the... found on D&B's Web site at http://fedgov.dnb.com/webform or by calling D&B, toll-free, at 1-866-705-5711...

  14. Culturas del Mundo

    DEFF Research Database (Denmark)

    Benwell, Ann Fenger; Costa, Alberto; Waehle, Espen

    2006-01-01

    ’Culturas del mundo. Colecciones del Museo Nacional de Dinamarca’ with Ann Fenger Benwell in Culturas del Mundo. Colecciones del Museo Nacional de Dinamarca, ed. Silvia Sauquet, Fundación "la Caixa", Barcelona 2006, pp. 31-39......’Culturas del mundo. Colecciones del Museo Nacional de Dinamarca’ with Ann Fenger Benwell in Culturas del Mundo. Colecciones del Museo Nacional de Dinamarca, ed. Silvia Sauquet, Fundación "la Caixa", Barcelona 2006, pp. 31-39...

  15. Where do we go with Union Catalogues?

    Directory of Open Access Journals (Sweden)

    Edmund Chamberlain

    2013-07-01

    Full Text Available The United Kingdom boasts union catalogues for its major research libraries, journal holdings, archives and, most recently, for its public library collections. For researchers wanting to locate material across the UK, such aggregations have long served as a first stop for researchers wanting to find the right material and also provided a showcase for our formidable research collections. In the global networked environment, search engines and social networks can fulfil much of the functionality of union catalogues and have become the natural places to which our users go for search and discovery, even in academic situations. Right now, there is a ‘disconnect’ between the data describing our collections and the places users first turn to start their searches. This can be fixed by exposing descriptive data to wider audiences beyond the silo of the local catalogue, but data publishing is a fast moving area with little obvious short-term institutional-level gain and some start-up barriers. Publishing library data to the open web at the level of a national aggregation would utilize existing skill sets and infrastructure, minimize risk and maximize impact.

  16. Energy policies of the European Union

    International Nuclear Information System (INIS)

    Lyons, P.K.

    1994-09-01

    This report takes stock of what has been achieved and where the European Community is going in terms of energy policy and also looks at the full extent of the Union's energy sector competances. The chapters deal with the European Commission's programme to create an internal energy market through implementing new Directives and by means of an approach through competition. A further two chapters concentrate on environmental policy with respect to emissions control and the greenhouse effect. Two broad policy areas - Community Initiative and trans-European networks - are examined in a consideration of the connections between energy and economic and social cohesion. Security of supply is the fourth and traditional pillar of energy policy to be considered. Three policy areas which do not fit into these first four categories are dealt with in individual chapters. These are: nuclear issues, research and development, and a wider Europe. A concluding chapter suggests that there is an urgent need for a new way of dealing with energy in the European Union which has a myriad of policies affecting energy but no energy policy. The appendices include a document summary for each of the main chapters and a glossary. (UK)

  17. Energy Union: a global road-map

    International Nuclear Information System (INIS)

    Tourneur, Jean-Claude

    2015-01-01

    This article presents and comments the strategy defined by the European Commission in its document entitled 'Energy Union: secure, sustainable, competitive, affordable energy for every European' which defines a framework and a road-map for the emergence and progress of a Europe of energy. Such an Energy Union means solidarity between members, a free circulation of energy across borders, a priority for energy efficiency, a transition towards a low carbon society, and competitive and affordable prices for the European citizen. The author outlines the present weaknesses of the Europe of energy: first world energy importer, twelve countries being under the required interconnection level (10 per cent of the installed production should be able to cross the borders), some countries depending on a unique provider for their energy imports, low energy performance for buildings and high oil-dependence for transports. On the other hand, good results have already been reached regarding the reduction of greenhouse gas emissions. To be successful, this new strategy thus requires high investments and the development of new standards

  18. Emerging Administrations under European Union Rules

    Directory of Open Access Journals (Sweden)

    Bogdan Berceanu

    2012-05-01

    Full Text Available The idea of emergence is generally used to indicate the appearance of patterns, structures, orproperties that cannot be adequately explained by referring only to the system’s pre-existing componentsand their interactions. The term “emergence” has an interdisciplinary approach specific to administrativesciences, too. In this article, the concept of “emergence” signifies lato sensu a kind of change and it will beused to refer to countries that have a high volatility and that are in transition and to define the changes thatsuffer the public administrations of the countries which are part of the European construction. EuropeanUnion through its policies and legislation has a great impact on economic and social conditions in MemberStates. The aim of the paper is to present a theoretical approach on the dimension of emergingadministrations understood as changes and reforms that suffer the institutions from the EU member statesunder the pressure of the European Union rules. The study is using the concept of emergence to researchand to analyze the nature of the changes in the public administration starting from the approach of thesystems theory.

  19. European union standards for tuberculosis care.

    Science.gov (United States)

    Migliori, G B; Zellweger, J P; Abubakar, I; Ibraim, E; Caminero, J A; De Vries, G; D'Ambrosio, L; Centis, R; Sotgiu, G; Menegale, O; Kliiman, K; Aksamit, T; Cirillo, D M; Danilovits, M; Dara, M; Dheda, K; Dinh-Xuan, A T; Kluge, H; Lange, C; Leimane, V; Loddenkemper, R; Nicod, L P; Raviglione, M C; Spanevello, A; Thomsen, V Ø; Villar, M; Wanlin, M; Wedzicha, J A; Zumla, A; Blasi, F; Huitric, E; Sandgren, A; Manissero, D

    2012-04-01

    The European Centre for Disease Prevention and Control (ECDC) and the European Respiratory Society (ERS) jointly developed European Union Standards for Tuberculosis Care (ESTC) aimed at providing European Union (EU)-tailored standards for the diagnosis, treatment and prevention of tuberculosis (TB). The International Standards for TB Care (ISTC) were developed in the global context and are not always adapted to the EU setting and practices. The majority of EU countries have the resources and capacity to implement higher standards to further secure quality TB diagnosis, treatment and prevention. On this basis, the ESTC were developed as standards specifically tailored to the EU setting. A panel of 30 international experts, led by a writing group and the ERS and ECDC, identified and developed the 21 ESTC in the areas of diagnosis, treatment, HIV and comorbid conditions, and public health and prevention. The ISTCs formed the basis for the 21 standards, upon which additional EU adaptations and supplements were developed. These patient-centred standards are targeted to clinicians and public health workers, providing an easy-to-use resource, guiding through all required activities to ensure optimal diagnosis, treatment and prevention of TB. These will support EU health programmes to identify and develop optimal procedures for TB care, control and elimination.

  20. The European Union and Iranian Nuclear Power

    International Nuclear Information System (INIS)

    Drevet, Jean-Francois

    2015-01-01

    On 14 July 2015, after 12 years of repeated crises around the nuclear issue and the ambitions of Iran in that regard, an agreement was finally signed between Tehran and the members of the UN Security Council plus Germany. Restriction on the enrichment of uranium and the production of plutonium, a strengthening of the inspection regime, the lifting of sanctions against Iran from 2016 onwards, maintaining the arms embargo - these are, broadly speaking, the outlines of this agreement. It will become clear over time how it is to be applied. Above and beyond these aspects, it is probably in the negotiation process that led to the agreement that the greatest lessons are to be learned, at least for the European Union. After reminding us of the context and the role played by economic and financial sanctions, Jean-Francois Drevet goes more precisely into the analysis of the new role the Union has assumed in this diplomatic territory, showing the extent to which 'soft power', as seen in this negotiation, could apply to other conflicts, beginning with those in the Middle East. (author)

  1. EUROPEAN UNION AND THE PROCESS OF GLOBALIZATION

    Directory of Open Access Journals (Sweden)

    Mihail CARADAICĂ

    2014-05-01

    Full Text Available What is the relation between globalization and the process of European integration? Does the European integration have its own way, or is it deeply dependent on globalization? Those are the main questions I will try to answer in this paper by using an alternative critical approach: neo-gramscianism. Neo-gramscianism is a historical materialist view on the European integration process and international political economy which offers a better understanding of the social changes in terms of social forces agency and super structural influence (the neoliberal ideology of globalization and European integration. My aim is to analyze the globalization process through a neo-gramscian theoretical framework and to observe how its main components affect European Integration. I will do this by assuming the definition of globalization provided by Andreas Bieler, who understands this process through three main pillars: transnationalization of finance, transnationalization of production and ideological shift from Keynesianism to neoliberalism. Finally I will try to formulate some conclusions regarding the emergence of European Round Table of Industrialists – the first lobby group of big capital at the European Union level – and Economic and Monetary Union – the internal market program that symbolizes the shift to neo-liberalism.

  2. The use of multivariate analysis to link sediment contamination and toxicity data to establish sediment quality guidelines: an example in the Gulf of Cadiz (Spain); El uso del analisis multivariante en la union de datos de toxicidad y contaminacion para establecer guias de calidad de sedimento: Un ejemplo en la Bahia de Cadiz (Espana)

    Energy Technology Data Exchange (ETDEWEB)

    Del Valls, T. Angel; Forja, Jesus M [Departamento de Quimica Fisica, Facultad de Ciencias del Mar, Universidad de Cadiz, Cadiz, (Spain); Gomez-Parra, Abelardo [Instituto de Ciencias Marinas de Andalucia, CSIC, Puerto Real, Cadiz, (Spain)

    1998-03-01

    which biological effects have been shown to be minimal (mg kg{sup -}1 dry sediment), are: Hg, 0.25; Ag, 0.78; Pb, 66.80; Cr, 101.2; LAS, 2.6. [Spanish] Para evaluar la calidad de los sedimentos marinos en el Golfo de Cadiz, los datos provenientes de concentraciones quimicas y respuestas de toxicidad en sedimentos fueron unidos usando el analisis ultivariante. Las muestras de sedimentos fueron recogidas sinopticamente en siete estaciones de dos ecosistemas litorales en el Golfo de Cadiz (cinco en la Bahia de Cadiz y dos en las marismas del rio Barbate) y fueron sujetas a seis tests de toxicidad de forma independiente y replicada, asi como a analisis quimicos. Los efectos toxicos en los sedimentos se chequearon utilizando tres fases operativas del sedimento: sedimento bruto, utilizando el anfipodo Microdeutopus gryllotalpa (10 d estatico: supervivencia) y la almeja de estuario Ruditapes philippinarum (48 h estatico: enterramiento); extracto de sedimento, utilizando larvas del bivalvo de estuario Crassostrea angulata (48 h estatico: supervivencia) y del pez marino Sparus aurata (48 h estatico: supervivencia); y agua intersticial, utilizando poblaciones del rotifero de estuario Brachionus plicatilis (7 d estatico: decaimiento de la poblacion) y de la bacteria marina Photobacterium phosphoreum (Microtox ). Para evaluar los niveles de contaminacion se determinaron las concentraciones en los sedimentos de carbono organico, 14 metales traza (Fe, Mn, Cu, Zn, Pb, Cd, Ag, Hg, As, Sn, V, Ni, Co y Cr) y el detergente alquibencenosulfonato lineal (LAS). Los resultados de los ensayos de toxicidad se compararon mediante relaciones de respuesta entre las diferentes estaciones, demostrando una concordancia general entre los valores de toxicidad determinados en todos los tests, excepto en el caso de la toxicidad en el agua intersticial (principalmente debido a mezclas de metales traza toxicas). Los datos obtenidos en los ensayos quimicos y de toxicidad se ensamblaron utilizando tecnicas

  3. Evolución del comercio exterior del vino del campo de Cariñena

    Directory of Open Access Journals (Sweden)

    María Concepción Estella Álvarez

    1998-01-01

    Full Text Available En este artículo se exponen las vicisitudes por las que ha atravesado el vino de Cariñena para su comercialización desde el siglo pasado. Comienza con el éxito y los altos precios del vino conseguidos por la demanda francesa, tras la invasión filoxérica del país vecino, favorecidos también por la inauguración del ferrocarril de vía estrecha Zaragoza-Cariñena y seguidos de la crisis de superproducción y consiguiente descenso de los precios tras finalizar el Tratado de Comercio con Francia. Luego se explica la lenta recuperación a lo largo de este siglo, se facilitan las cantidades exportadas en el último cuarto del mismo, para analizar de forma más exhaustiva la situación del mercado exterior en la actualidad, donde el comercio europeo ha vuelto a ser el más importante y de modo especial el de la Unión Europea.In this article the different mishaps that the Cariñena wine has undergone to be commercialized since the last century are shown. The study begins with the success and the high price of the wine, due to the French demand, after the phylloxera invasión in the neighbouring country, also favoured by the opening of the narrow-gauge railway Zaragoza-Cariñena, and followed by the superproduction crises and the subsequent fall of the prices after the end of the Commercial Treaty with France. Afterwards, we explain the slow recovery along this century, giving the exported quantities in the last quarter of the century, and then analyzing more thoroughiy the situation of the foreign market nowadays, since the European trade has regained importance, specially the one in the European Union.

  4. COURT OF JUSTICE OF THE EUROPEAN UNION - INTERNATIONAL COURT

    Directory of Open Access Journals (Sweden)

    Ioana Nely Militaru

    2015-11-01

    Full Text Available Court of Justice of the European Union (CJEU performs according to its competence, the position of International Justice in solving disputes between two or more subjects of international law. International jurisdiction of the Court of Justice of the EU is - mandatory that each Member State has the opportunity to seize this court if it considers that another state violated an obligation incumbent upon it under Union Treaties; - optional in disputes between Member States in connection with the subject Union Treaties.

  5. The Effects of Corruption in a Monetary Union

    OpenAIRE

    Garcia Fortuny, Judit

    2015-01-01

    Many countries around the world suffer from corruption. In a monetary union, corruption varies from one country to another. It is possible corruption in one country may affect another country in a monetary union. We demonstrate that this feature has important implications in a monetary union with two asymmetric countries. Country 1 has a corrupted government while country 2 does not. Within this framework, we determine under which conditions corruption damages or benefits both countr...

  6. Employment, Family Union, and Childbearing Decisions in Great Britain

    OpenAIRE

    Arnstein Aassve; Simon Burgess; Matt Dickson; Carol Propper

    2004-01-01

    The paper investigates the relationship between work and family life in Britain. Using appropriate statistical techniques we estimate a five-equation model, which includes birth events, union formation, union dissolution, employment and non-employment events. The model allows for unobserved heterogeneity that is correlated across all five equations. We use information from the British Household Panel Survey, including the retrospective histories concerning work, union, and child bearing, to e...

  7. Organising methods and member recruitment in Irish Trade Unions

    OpenAIRE

    Turner, Thomas; O'Sullivan, Michelle; D'Art, Daryl

    2011-01-01

    peer-reviewed Purpose This paper explores the recruiting and organising methods used by Irish full-time union officials to recruit new members in the private sector of the economy. Design/methodology/approach The analysis is based on a survey of full-time union officials in eight Irish trade unions. Findings Results indicate that the use of organising techniques by officials had no significant impact on changes in membership numbers but did have a significant and po...

  8. Union decline in Britain: Is chauvinism also to blame?

    OpenAIRE

    Haile, Getinet Astatike

    2012-01-01

    The paper examines if workplace gender diversity offers some explanation for the decline of unions in Britain. Using the WERS2004 linked employer-employee data and alternative econometric estimators it reports an inverse relationship between workplace union density and gender diversity. Gender and ownership status based sub-group analyses suggest the inverse relationship to be stronger for male union members and those in the private sector. Gender group size based analysis reveals a positive ...

  9. Utilidad en la combinación de oligonucleótidos universales para la detección del virus del papiloma humano en cáncer cervicouterino y lesiones premalignas Usefulness of combining universal oligonucleotides in detecting human papillomavirus in cervical cancer and premalignant lesions

    Directory of Open Access Journals (Sweden)

    Adela Carrillo

    2004-02-01

    juegos de oligonucleótidos universales que reconocen la región L1 del VPH. Con una adecuada toma de muestra, el análisis para detección de ADN en exudado cérvico-vaginal es una buena alternativa de diagnóstico del VPH.OBJECTIVE: To determine the prevalence of human papillomavirus (HPV infection at different stages of the natural history of cervical cancer. Also, to optimize its detection by means of different sets of general primers. MATERIAL AND METHODS: A descriptive, cross-sectional study was conducted between January and December 1999. Samples were processed and analyzed at the Instituto Nacional de Cancerología (National Cancerology Institute in Mexico City. A comparative analysis was performed using Student's t for continuous values and the chi-squared test for proportions. A contingency analysis was made between biopsy and cervical exudates with the Kappa statistic. HPV detection was done by PCR with general primers which recognize different regions of the L1 gene (MY09/11; GP5/6; L1C1/2 and with HPV16- and HPV18- specific primers, as well as direct sequencing of PCR products. RESULTS: In total, 154 samples were analyzed: 65 (42.2% of them showed normal cytology; 45 (29.2% high and low grade lesions; and 44 (28.6% invasive cervical cancer. HPV was detected in 95.5% of invasive cervical cancers, in 91.6% of high grade lesions, in 66.7% of low grade lesions, and in 23.1% of normal smears, by PCR with at least one set of oligonucleotide primers. HPV detection was more efficient in biopsy specimens than in cervical scrapes. The total percentage of HPV detection us ing only one set of universal oligonucleotides (37.6%increased to 60.4% when the other two sets of universal oligonucleotides were used. CONCLUSIONS:The frequency of high risk HPV is high even in women with reported normal cytology. HPV detection improves when different sets of general primers directed to the L1 region are used. HPV DNA screening in cervical scrapes may be a good alternative HPV

  10. Direct Tax Applications in Relationship Between European Union and Turkey

    OpenAIRE

    YAZARKAN, Hakan; MEZARARKALI, Pınar

    2015-01-01

    European Union (EU) is an economic union that exstipulates common tax policy within the union without interfering the taxes which collected by the members. On the other hand union doesn’t put tax systems of member states to harmonization but has a positive look on efforts convergence. The reason of this is the difference between international tax ratio causes limiting even hindering the capital activities. Turkey which made an application at 31st of July 1959 still can’t become member of EU. ...

  11. The Euratom supply agency. A small ENERGY UNION?

    Energy Technology Data Exchange (ETDEWEB)

    Blohm-Hieber, Ute [European Commission, Luxembourg (Luxembourg). Unit - Nuclear Fuel Market Operations

    2015-11-15

    In the 1950s, when the European Communities were founded the ECSC (Treaty establishing the European Coal and Steel Community), concluded for 50 years and the EURATOM Treaty (Treaty establishing the European Atomic Energy Community), with unlimited validity, were signed. On the present political agenda of the European Union, energy supply security has a high priority. The Juncker Commission therefore focusses on the concept of an Energy Union. The Euratom Treaty provides one successful example of a ''small sectorial Energy Union'' and may serve as stimulation for reflections for the Energy Union in other sectors.

  12. The principle of empowerment in the European Union

    Directory of Open Access Journals (Sweden)

    Ioana Nelly MILITARU

    2011-12-01

    Full Text Available Delimitation of competences in the EU is governed by the principle of conferral. Based on the content of these provisions work in the first three parts of it, defining and classifying skills appropriate attribution Treaties underlying the European Union (Treaty on European Union and the Treaty on the Functioning of the European Union and the Court of Justice. The next three parts of the paper detailing each classification in hand, highlighting, clear delineation of the Union competences of the Member States carried out by the Lisbon Treaty and the amendments made by this treaty.

  13. Official Union Time Tracking System Operational Data Store

    Data.gov (United States)

    Social Security Administration — Official Union Time Tracking System captures the reporting and accounting of the representational activity for all American Federation of Government Employees (AFGE)...

  14. Endoscopic localization of colorectal cancer: Study of its accuracy and possible error factors Localización endoscópica del cáncer colorrectal: estudio de su precisión y posibles factores de error

    Directory of Open Access Journals (Sweden)

    Fernando Borda

    2012-11-01

    Full Text Available Introduction: accurate preoperative localization of colorectal cancer (CRC is very important, with a wide range of published error rates. Aim: to determine accuracy of endoscopic localization of CRC in comparison with preoperative computed tomography (CT. To analyse variables that could be associated with a wrong endoscopic localization. Patients and methods: endoscopic and CT localization of a series of CRC without previous surgery were reviewed. We studied the concordance between endoscopic and radiologic localization against operative findings comparing accuracy of endoscopy and CT. We analysed the frequency of wrong endoscopic diagnoses with regard to a series of patient, endoscopy and tumor variables. Results: two hundred thirty seven CRC in 223 patients were studied. Concordance with surgical localization was: colonoscopy = 0.87 and CT = 0.69. Endoscopic localization accuracy was: 91.1%; CT: 76.2%: p = 0.00001; OR = 3.22 (1.82-5.72. Obstructive cancer presented a higher rate of wrong localization: 18 vs. 5.7% in non-obstructive tumors (p = 0.0034; OR = 3.65 (1.35-9.96. Endoscopic localization mistakes varied depending on tumor location, being more frequent in descending colon: 36.3%, p = 0.014; OR = 6.23 (1.38-26.87 and cecum: 23.1%, p = 0.007; OR = 3.92 (1.20-12.43. Conclusions: endoscopic accuracy for CRC localization was very high and significantly better than CT accuracy. Obstructive tumor and those located in the descending colon or cecum were associated with a significant increase of the error risk of CRC endoscopic localization.Introducción: una correcta localización preoperatoria del cáncer colorrectal (CCR es muy importante, siendo variables las tasas de error de localización endoscópica publicadas. Objetivo: determinar la precisión de la localización endoscópica del CCR, comparándola con la del TAC preoperatorio. Analizar las variables que pudieran asociarse a una localización endoscópica errónea. Pacientes y m

  15. The role of union support in coping with job insecurity: A study among union members from three European countries

    OpenAIRE

    Sjoerd Goslinga; Johnny Hellgren; Antonio Chirumbolo; Hans De Witte; Katharina Näswall; Magnus Sverke

    2005-01-01

    The present study examines the potential moderating role of union support in the relationship between job insecurity and work-related attitudes and well-being of unionised employees. Survey data collected among union members from three European countries (The Netherlands, Italy and Sweden) indicate that job insecurity is associated with reduced levels of job satisfaction, well-being and organisational commitment. Contrary to expectations, union support moderated neither the effect of job inse...

  16. Citología de cuello uterino e impeditividad eléctrica en la detección temprana del cáncer cervical Cervical Cytology and Electrical Impedivity in the Early Detection of the Cervical Cancer

    Directory of Open Access Journals (Sweden)

    Sandra P. Corzo

    2012-12-01

    Full Text Available Se reportan los resultados de un estudio piloto de las propiedades eléctricas del tejido epitelial de cuello uterino por medio de espectroscopia de impeditividad eléctrica, con el propósito de estudiar la detección temprana de la neoplasia intraepitelial con éste método. Para ello, se midieron 636 espectros de impeditividad eléctrica en 53 pacientes de la Liga Santandereana de Lucha Contra el Cáncer, los cuales fueron comparados con las citologías cervicales. Los datos experimentales fueron ajustados al modelo de Cole-Cole con una herramienta computacional basada en algoritmos genéticos. Los resultados del estudio realizado sugieren una sensibilidad y especificidad superiores al 70%. Salud UIS 2012; 44 (2:15-19Are reported the results of a study about the properties of cervical epitelial tissue using electrical impeditivity spectroscopy, with the objective of studying the early detection of intraepithelial neoplasia, with this metled. 636 impedivity spectrums from 53 patients at Liga Santandereana de Lucha contra el cancer were measured and compared with cervical cytology. Experimental data were felted to the Cole-Cole model, using a computational tool based in genetic algorithms. The results of the study suggest a sensibility and specificity above 70%. Salud UIS 2012; 44 (2:15-19

  17. Opting Out of the European Union

    DEFF Research Database (Denmark)

    Adler-Nissen, Rebecca

    controversial cases of differentiated integration: the British and Danish opt-outs from Economic and Monetary Union and European policies on borders, asylum, migration, internal security and justice. Drawing on over one hundred interviews with national representatives and EU officials, the author demonstrates......European integration continues to deepen despite major crises and attempts to take back sovereignty. A growing number of member states are reacting to a more constraining EU by negotiating opt-outs. This book provides the first in-depth account of how opt-outs work in practice. It examines the most...... how representatives manage the stigma of opting out, allowing them to influence even politically sensitive areas covered by their opt-outs. Developing a practice approach to European integration, the book shows how everyday negotiations transform national interests into European ideals. It is usually...

  18. Nuclear power in the Soviet Union

    International Nuclear Information System (INIS)

    Ponomarev-Stepnoi, N.N.

    1989-01-01

    The pros and cons of nuclear power are similar in many countries, but the following pro factors are specific to the Soviet Union: the major sources of conventional fuel are in one area of the country, but energy consumption is concentrated in another; and a large portion of energy is generated using oil and gas. The arguments against nuclear power are as follows: safety requirements and expectations have been increased; and public opinion is negative. A program of nuclear power generation has been developed. New techniques are being implemented to increase safety and enhance operations of different types of nuclear power plants. Its should be obvious in the future that a nuclear power plant has better economic and environmental parameters than existing methods of power generation

  19. On the union of graded prime ideals

    Directory of Open Access Journals (Sweden)

    Uregen Rabia Nagehan

    2016-01-01

    Full Text Available In this paper we investigate graded compactly packed rings, which is defined as; if any graded ideal I of R is contained in the union of a family of graded prime ideals of R, then I is actually contained in one of the graded prime ideals of the family. We give some characterizations of graded compactly packed rings. Further, we examine this property on h – Spec(R. We also define a generalization of graded compactly packed rings, the graded coprimely packed rings. We show that R is a graded compactly packed ring if and only if R is a graded coprimely packed ring whenever R be a graded integral domain and h – dim R = 1.

  20. THE COMPETITION POLICY IN THE EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    Dumitriţa Florea (Ionescu

    2012-09-01

    Full Text Available The idea of European unity dates back to antiquity, the time when the Roman Empire alsopursued such a goal. Attempts to unify European countries have appeared constantly in history, but theirsuccessful culmination crystallized only after the Second World War.Basically, the two wars have led to the downfall of Europe and the loss of its centenary political andmilitary position. The experience of these wars has led the states to initiate a defense mechanism of peace,security and international cooperation - resulted in creating an organization of universal jurisdiction -TheLeague of Nations. However, the successor of this organization, The United Nations - was one thatmanaged thorough its collective security system represented by the Security Council, to ensure andmaintain universal / global peace until now (Stelian Scăunaş, 2005.The creation of the European Union is based on four founding treaties: The Treaty establishingThe European Coal and Steel Community (ECSC - adopted in Paris on April 18, 1951, entered into forcein 1952 - treaty concluded for a period of 50 years and that has terminated in 2002, The Treatyestablishing the European Economic Community (EEC, The Treaty establishing the European AtomicEnergy Community (EAEC or EURATOM, both signed in Rome on March 25, 1947 and entered into forcein 1958 as the Treaties of Rome, and The Treaty on the European Union, which was adopted at Maastrichton 7th of February 1992 and entered into force in 1993. To these institution treaties we can add themodifying treaties of the founding treaties, including: The Merger Treaty - adopted in Brussels on 8 April1965, entered into force in 1967; The Single European Act - signed in Luxembourg and Hague in 1986,entered into force in 1987; The Amsterdam Treaty - signed on October 2, 1997, entered into force in 1999,The Treaty of Nice - signed on February 26, 2001, entered into force in 2003, The Lisbon Treaty signed in2007 and entered into force on December 1st

  1. International Astronomical Union Sympoisum No.50

    CERN Document Server

    Westerlund, B

    1973-01-01

    Dr J. Landi Dessy, Director of the Astronomical Observatory, Cordoba, Argentina, invited the International Astronomical Union to hold a Symposium in Cordoba in connection with the celebration of the Centennial of the Cordoba Observatory; the date of foundation is October 24, 1871. He proposed that the Symposium should deal with Spectral Classification and Multicolour Photometry as seven years had elapsed since the Symposium No. 24 in Saltsj6baden, and much development had occurred in the field. The invitation and the proposal were accepted by the IAU, and the Symposium was held in Villa Carlos Paz, near Cordoba, between October 18 and October 24, 1971. It was attended by about 50 scientists representing Argentina, Canada, Chile, Den­ mark, France, Germany, Italy, Mexico, Sweden, Switzerland, U.K., U.S.A., Vatican City State and Venezuela. The Symposium was divided into four sessions: 1. Classification of slit spectra, 2. Classification of objective-prism spectra, 3. Photometric classification, 4. Catalogues ...

  2. Knowledge based economy in European Union

    Directory of Open Access Journals (Sweden)

    Ecaterina Stănculescu

    2012-04-01

    Full Text Available Nowadays we assist at a fundamental change from the economy based mainly on resources to the one based mostly on knowledge. The concept has been launched in the last decade of the past century. The knowledge became a production agent and a value creation instrument for whatever country and of course for an entire community like European Union which is constantly concerned by its development and competitiveness. This paper presents the principal characteristics of the present EU preoccupations with the expansion of a knowledge based economy through the 2020 European Development Strategy for smart, sustainable and inclusive economy, and especially for the Framework Programs (Framework Programme 7 and Competitiveness and Innovation Framework Programme.

  3. Redistributive Politics in a Political Union

    DEFF Research Database (Denmark)

    Citi, Manuele; Justesen, Mogens Kamp

    One of the main functions of centralized budgets in federal and political unions is to act as an equalizing mechanism to support economic cohesion. This is also the case with the European Union’s budget, which operates as a redistributive mechanism that counteracts the cross-national and cross...... remarkably over the last decades. In this paper, we investigate how and why the net fiscal position of each member state towards the rest of the EU changes over time. Using a novel panel dataset (1979-2014), we study how some key national and EU-level political and economic variables affect the EU...... find that the political orientation of national governments does not per se influence redistributive politics with in the EU. However, when the unemployment rate is rising, right-wing governments are able to extract significantly larger budgetary benefits....

  4. DEBATE ON ROMANIA INTEGRATION IN EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    Roxana M. SÎRBU

    2014-04-01

    Full Text Available The purpose of this paper is to analyze the current state of Romanian integration into the European Union through the analysis of statistical data related to the absorption way of structural and cohesion funds available in 2007-2013 (absorption indicators and economic competitiveness indicators: Gross Domestic Product, employment rate, unemployment, population. In addition there are analyzed the structural and cohesion funds available for Romania in 2014-2020, for each category of available operational program and also the measures that must be implemented for Romania to adapt in a performance way to Europe 2020. The analysis results are considered as prerequisites for the development of an underlying model of investment decisions in the integrated sustainable development of Romania.

  5. Radon therapy in the Soviet Union

    International Nuclear Information System (INIS)

    Sansoni, B.; Andrejew, S.V.

    1991-08-01

    In the Soviet Union approximately one million courses of radon treatment each lasting three weeks are prescribed every year. The curative application of radon used for cardiovascular diseases, including aftercare in cases of cardiac infarction, disorders of the locomotor system and joints and muscles, the male and female sexual system, diseases of the nervous system, endocrinology and metabolic diseases. Contraindication practice is similar to that in Central Europe. Radon is given to skin stimulation by wet and above all dry baths. The radiation exposure of patients from these three-week radon treatments is relatively low. The radon effect is interpreted as 'radiation flash' stimulating the nervous system. The skin plays a particular role in this process, acting as the stimulus acceptor. (orig./MG) [de

  6. DIRECT TAXATION IN ROMANIA AND EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    Gabriela DOBROTĂ

    2010-06-01

    Full Text Available Taxation is a historical result of the social, political and economic environment in a state. At the same time, the development of a state depends a lot on the history of its own tax system, on the way it is conceived and operates. The establishment of budgetary incomes has to be made in accordance with the requirements related to yield, efficacy, equity. The plurality of these tasks as well as political, economical, administrative constraints have materialized in the application of a gradual reform in Romania after passing to market economy. Its application has not always had the foreseen effects, repeated legislative alterations leading to investors’ discouraging and to difficult enforcement of the legislation at the level of economic agents and fiscal bodies. The paper presents aspects of direct taxation on the economic environment from Romania as well as comparisons with the state of the European Union.

  7. DIRECT TAXATION IN ROMANIA AND EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    Gabriela DOBROTĂ

    2010-09-01

    Full Text Available Taxation is a historical result of the social, political and economic environment in a state. At the same time, the development of a state depends a lot on the history of its own tax system, on the way it is conceived and operates. The establishment of budgetary incomes has to be made in accordance with the requirements related to yield, efficacy, equity. The plurality of these tasks as well as political, economical, administrative constraints have materialized in the application of a gradual reform in Romania after passing to market economy. Its application has not always had the foreseen effects, repeated legislative alterations leading to investors’ discouraging and to difficult enforcement of the legislation at the level of economic agents and fiscal bodies. The paper presents aspects of direct taxation on the economic environment from Romania as well as comparisons with the state of the European Union.

  8. European Union's environmental strategy

    International Nuclear Information System (INIS)

    Fitoussi, Jean-Paul; Laurent, Eloi; Le Cacheux, Jacques

    2007-01-01

    Environmental policy is an art of execution. Hence the fact that European Union member states have recently managed to agree on targets of emissions to fight climate change leaves open the question of how they will meet them. Economics cannot but embrace the scientific consensus on climate change and cannot say much about the efficiency of alternative technologies. Yet, its expertise is valuable to calculate economic effects and fairness of policies and to assess the relevance of incentives structures and effectiveness of institutions put into place to convert scientific consensus into action. This article is concerned with this latter point: does the EU have the right institutions to fight climate change? We claim that such is not the case, and offer to institute a 'European Community of Environment, Energy and Research' to go forward. Initially published in 'Revue de l'OFCE' No. 102

  9. Energy corridors European Union and Neighbouring countries

    International Nuclear Information System (INIS)

    Van Oostvoorn, F.; Hafner, Manfred; Vailati, Ricardo; Wietschel, Martin

    2007-08-01

    The ENCOURAGED (Energy corridor optimisation for European markets of gas, electricity and hydrogen) project has been launched in beginning 2005 to identify and assess the economically optimal energy corridors between European Union (EU) and neighbouring countries. The objectives of the project are to: Assess the economic optimal energy (electricity, gas and hydrogen) corridors and related network infrastructure for connecting the EU with its neighbouring countries and regions; Identify, quantify and evaluate the barriers to and potential benefits of building optimal energy corridors connecting the EU with its neighbours; Propose necessary policy measures to implement the recommended energy corridors with a focus on investment and the geopolitical framework; Organise stakeholder workshops and seminars to discuss the results and findings and reach consensus among scientists, stakeholders and non-governmental organizations and validate project results

  10. The Rise of a European Healthcare Union

    DEFF Research Database (Denmark)

    Vollaard, Hans; Martinsen, Dorte Sindbjerg

    2017-01-01

    Healthcare has only slowly appeared on the European Union’s (EU) policy agenda. EU involvement in policies concerning the organization, financing and the provision of diagnosis, care and cures to ill people developed along three fragmented tracks: (a) EU public health policies concerning the well......-being of all people; (b) the application of the free movement principle to national healthcare systems in particular by the EU’s Court of Justice (CJEU); and (c) the austerity packages and the stricter EU surveillance of national budgets since the debt crises. The key questions of this special issue...... are whether this fragmented EU involvement has now developed into a distinct European healthcare union, and if so what its driving forces have been. Thus, it explores how European integration in healthcare has moved forward despite widespread reluctance. It also examines the underexplored political dynamics...

  11. Laboratory medicine in the European Union.

    Science.gov (United States)

    Oosterhuis, Wytze P; Zerah, Simone

    2015-01-01

    The profession of laboratory medicine differs between countries within the European Union (EU) in many respects. The objective of professional organizations of the promotion of mutual recognition of specialists within the EU is closely related to the free movement of people. This policy translates to equivalence of standards and harmonization of the training curriculum. The aim of the present study is the description of the organization and practice of laboratory medicine within the countries that constitute the EU. A questionnaire covering many aspects of the profession was sent to delegates of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) and Union Européenne de Médecins Spécialistes (UEMS) of the 28 EU countries. Results were sent to the delegates for confirmation. Many differences between countries were identified: predominantly medical or scientific professionals; a broad or limited professional field of interest; inclusion of patient treatment; formal or absent recognition; a regulated or absent formal training program; general or minor application of a quality system based on ISO Norms. The harmonization of the postgraduate training of both clinical chemists and of laboratory physicians has been a goal for many years. Differences in the organization of the laboratory professions still exist in the respective countries which all have a long historical development with their own rationality. It is an important challenge to harmonize our profession, and difficult choices will need to be made. Recent developments with respect to the directive on Recognition of Professional Qualifications call for new initiatives to harmonize laboratory medicine both across national borders, and across the borders of scientific and medical professions.

  12. Tackle injuries in professional Rugby Union.

    Science.gov (United States)

    Quarrie, Kenneth L; Hopkins, Will G

    2008-09-01

    The tackle is the most dangerous facet of play in rugby union, but little is known about risk factors for tackle injuries. To estimate the injury risk associated with various characteristics of tackles in professional rugby union matches. Descriptive epidemiology study. All 140 249 tackles in 434 professional matches were coded from video recordings for height and direction of tackle on the ball carrier, speed of tackler, and speed of ball carrier; injuries were coded for various characteristics, including whether the tackler or ball carrier required replacement or only on-field assessment. There were 1348 injury assessments requiring only on-field treatment and 211 requiring player replacement. The inciting event and medical outcomes were matched to video records for 281 injuries. Injuries were most frequently the result of high or middle tackles from the front or side, but rate of injury per tackle was higher for tackles from behind than from the front or side. Ball carriers were at highest risk from tackles to the head-neck region, whereas tacklers were most at risk when making low tackles. The impact of the tackle was the most common cause of injury, and the head was the most common site, but an important mechanism of lower limb injuries was loading with the weight of another player. Rates of replacement increased with increasing player speed. Strategies for reducing tackle injuries without radically changing the contact nature of the sport include further education of players about safe tackling and minor changes to laws for the height of the tackle.

  13. Monetary Union is the future of EAEU

    Directory of Open Access Journals (Sweden)

    Vyacheslav S. Kuznetsov

    2015-01-01

    Full Text Available The president of Russian Federation V. Putin's Order from the 10th of March 2015 to the Government and Central Bank of Russia to work on the plan of creating Monetary Union of EAEU by the 1st of September cannot be ignored by scientific community's attention of Russia and other Eurasian countries. Strategic goal of this document is pretty clear - to create an island of currency stability in the surrounding of Jamaica's Monetary nonsystem and existing monopolar and assimetric world's dollar order, to minimize the dependency of Eurasian countries on US dollar, to hold its world expansion, to freeze the process of financing of USA imbalances by all countries, to turn back the process of dollarization of Eurasian countries and world's dollarization and relieve the world's community from future financial crises. The world's financial and economic crisis of 2008-2010 has clearly shown that US monetary, credit and banking system has become a permanent source of future turmoil of world's scale. It creates a necessity to activate the process of monetary integration of countries on the regional level and transformation of the modern Jamaica's world's dollar standard into the world's multipolar monetary standard. In this article the author analyses he stages of setting up the Eurasian regional monetary order from the creation of multilateral settlement system using common regional currency unit to the introduction of Eurasian currency system with Eurasian currency unit, which can be transformed in the future into the Eurasian Economic and monetary union with common regional currency (euras, which can restrict the world's monopoly position of the dollar.

  14. Panorama epidemiológico de la mortalidad por cáncer en el Instituto Mexicano del Seguro Social: 1991-1995 Epidemiologic panorama of cancer mortality in the Mexican Institute of Social Security: 1991-1995

    Directory of Open Access Journals (Sweden)

    JORGE SALMERÓN-CASTRO

    1997-07-01

    Full Text Available Objetivo. Describir el comportamiento de la mortalidad global por cáncer, así como la mortalidad específica para las principales neoplasias malignas en población adulta derechohabiente (DH del Instituto Mexicano del Seguro Social (IMSS. Material y métodos. A partir de los registros oficiales de defunción y de la información sobre la población para los años 1991-1995, se estimaron las tasas anuales de mortalidad global y específica para las 10 principales neoplasias malignas por sexo, en mayores de 20 años. Asimismo, se estimaron las tendencias nacionales y estatales para las principales neoplasias malignas para cada sexo por medio de regresión de Poisson. Se calcularon las diferencias de tasas de mortalidad específica para las dos principales neoplasias por sexo restando las tasas estatales a su respectiva tasa nacional en 1995. Resultados. La mortalidad global por cáncer en los hombres se incrementó de 76.2 en 1991, a 94.8 por 100 000 DH en 1995; entre las mujeres, ésta se incrementó de 85.6 a 105.8 por 100 000 DH, representando un incremento de 24.4 y de 24% en hombres y mujeres, respectivamente, durante el periodo de estudio. Entre los hombres las neoplasias de riñón, leucemia, páncreas, próstata y pulmón; y entre mujeres las de colon, mama, páncreas, leucemias e hígado, mostraron los incrementos más significativos. Conclusiones. En el IMSS es impostergable la conformación de un registro poblacional de cáncer que permita una mejor vigilancia epidemiológica de las neoplasias y una evaluación permanente del impacto de programas específicos para la prevención y control de este padecimiento en las instituciones.Objective. This paper describes the global cancer mortality and the specific mortality patterns for the main neoplasms among adult members of the Mexican Institute of Social Security (IMSS. Material and methods. Using official death certificates and information about the population of the IMSS members during

  15. Fortalezas y debilidades del programa para la detección y el control del cáncer cervicouterino: Evaluación cualitativa en San Luis Potosí, México Strengths and weaknesses of a cervical cancer detection and control program: a qualitative evaluation in San Luis Potosi, Mexico

    Directory of Open Access Journals (Sweden)

    Luz María Tejada-Tayabas

    2012-08-01

    Full Text Available Objetivo: Identificar, desde la perspectiva del personal de salud, las fortalezas y debilidades del programa para la detección y el control del cáncer cervicouterino mediante una evaluación cualitativa, en tres centros de salud de San Luis Potosí, México, entre agosto de 2008 y noviembre de 2009. Métodos: Se realizó una evaluación cualitativa. En el estudio participaron nueve prestadores de servicios, seleccionados mediante muestreo por conveniencia, bajo el criterio de participación voluntaria. Inicialmente se obtuvo información de los centros de salud para conocer las características y el contexto en que opera el programa; posteriormente, a los nueve informantes se les realizaron 18 entrevistas semiestructuradas para indagar su perspectiva. Se empleó un análisis de contenido dirigido. Resultados: Las fortalezas referidas por el personal son el carácter gratuito del programa, la disponibilidad de recursos materiales, así como algunas estrategias que facilitan la captación de mujeres y su acceso al cribado. Las principales debilidades son las limitaciones de recursos humanos y en la estructura física, la ineficiente organización de actividades, la deficiente capacidad técnica del personal y las limitadas acciones de promoción, así como las dificultades en el seguimiento de las mujeres con resultados positivos. Conclusiones: Este estudio muestra la necesidad de incrementar los recursos humanos, realizar cambios en la normatividad y reorganizar las acciones del programa en algunos centros de salud, para garantizar la calidad del servicio y satisfacer los requerimientos de las mujeres, y así favorecer la cobertura en todas sus acciones.Objective: To identify, from the perspective of the health staff, the strengths and weaknesses of the program for the detection and control of cervical cancer through a qualitative assessment implemented in three health centers in the city of San Luis Potosi, Mexico, from August 2008 to November

  16. Epidemiology of gastric cancer and perspectives for prevention Epidemiología del cáncer gástrico y perspectivas para su prevención

    Directory of Open Access Journals (Sweden)

    NUBIA MUÑOZ

    1997-07-01

    Full Text Available The most recent estimates of the world-wide incidence of cancer indicate that gastric cancer was in 1990 the second most frequent cancer in the world (after lung cancer, with about 900 000 new cases diagnosed every year. Steady declines in the rates have been observed everywhere in the last few decades, but the absolute number of new cases per year is increasing mainly because of ageing of the population. The exact causes of the decline of gastric cancer are not well understood, but must include improvements in diet, food storage (e.g., refrigeration and, possibly, the decline of Helicobacter pylori infection. Dietary modifications and, possibly, vitamin supplements remain one of the most important tool for the prevention of gastric cancer. Control of H. pylori infection, by means of eradication or immunization, is also likely to offer great potential for the prevention of this important malignancy.Las estimaciones más recientes sobre la incidencia de cáncer a nivel mundial indican que, en 1990, el gástrico fue el segundo más frecuente (después del pulmonar, con aproximadamente 900 000 casos nuevos diagnosticados cada año. Durante las últimas décadas, las tasas de incidencia de esta enfermedad han disminuido en forma constante en casi todo el mundo; sin embargo, el número absoluto de casos nuevos por año continúa en aumento debido, primordialmente, a que la población cuenta con un mayor número de personas de edad avanzada. No se sabe con exactitud a qué se debe esta disminución de casos de cáncer gástrico, pero entre las causas se mencionan: mejoras tanto en la dieta como en la conservación de los alimentos (p.e., por medio de la refrigeración y una disminución de las infecciones por Helicobacter pylori. Las modificaciones a la dieta y, posiblemente, el consumo de complementos vitamínicos continúan siendo las alternativas más importantes para prevenir el cáncer gástrico. Asimismo, es probable que el control de la infecci

  17. Customs unions, currency crises, and monetary policy coordination: The case of the Eurasian Economic Union

    Directory of Open Access Journals (Sweden)

    Evgeny Vinokurov

    2017-09-01

    Full Text Available After achieving substantial progress in establishing a common customs territory and regulations, customs unions face potential disruptions due to a lack of monetary policy coordination. These disruptions might appear in the form of currency shocks and the ensuing trade conflicts. We approach this issue by looking at the case of the Eurasian Economic Union (EAEU. The volatility of national currencies in 2014–2015 resulted in sizable shifts in competitiveness, culminating in a currency crisis in some member states. This raises the questions of how to gradually achieve a more coordinated monetary policy, what monetary policy options are available, and what would be their relative impact on macroeconomic stability. Using a set of modeling tools and econometric models, we review three monetary regimes, which represent moves from fully independent exchange rate policy through increased policy coordination to joint exchange rate setting.

  18. The Labour Relations Act, majoritarianism and union structure

    African Journals Online (AJOL)

    1 INTRODUCTION. The new Labour Relations Act 66 of 1995 (LRA) has been viewed by many ... economic and political changes being experienced in South Africa since ... unions perpetuates fragmentation of a union movement and weakens workers ... particular geographic areas. A good ... international labour standards.

  19. Limiting organisational rights of minority unions: POPCRU v ...

    African Journals Online (AJOL)

    ... current socioeconomic and political landscape. Strike violence, loss of confidence in existing bargaining structures, and the alienation of vulnerable employees from majority unions has resulted in minority unions taking up the cudgels of frustrated and disempowered employees, as witnessed in the Marikana experience.

  20. Work reorganisation and technological change: limits of trade union ...

    African Journals Online (AJOL)

    This article suggests that this unidimensional strategy meant that building the union's capacity was neglected, reducing its ability to respond proactively to technological innovation and work reorganisation. While it does not present union capacity as a panacea, the article presents international examples that indicate that ...

  1. Trade Unions as Organisations: Key Issues and Problems of Internal ...

    African Journals Online (AJOL)

    The paper critically examines and evaluates inter alia Trade Unions as. Organisations and the key issues and problems of Internal Democracy within them. It transcends this analysis to assert that these core issues apply equally well to Political Organisations. Thus, from an ideological standpoint, Trade Unions play a great ...

  2. Politics and Policies of Promoting Multilingualism in the European Union

    Science.gov (United States)

    Romaine, Suzanne

    2013-01-01

    This article examines the politics of policies promoting multilingualism in the European Union (EU), specifically in light of the recently released European Union Civil Society Platform on Multilingualism. As the most far-reaching and ambitious policy document issued by the European Commission, the Platform warrants close scrutiny at a significant…

  3. 76 FR 18198 - European Union-United States Atlantis Program

    Science.gov (United States)

    2011-04-01

    ... DEPARTMENT OF EDUCATION European Union-United States Atlantis Program AGENCY: Office of...)--Special Focus Competition: European Union-(EU) United States (U.S.) Atlantis Program Notice inviting... and Culture, European Commission for funding under a separate but parallel EU competition. Within this...

  4. Physical fitness of elite female Rugby Union players | Hene | African ...

    African Journals Online (AJOL)

    Rugby union is a contact sport in which players require high levels of physical fitness, which is a composite of aerobic and anaerobic endurance, muscle strength and power, speed, agility and body composition. The aim of this study was to assess the physical fitness characteristics of elite female rugby union players.

  5. Organization and regulation of energy markets in the European Union

    International Nuclear Information System (INIS)

    Vasconcelos, J.

    2002-01-01

    The energy regulation policy and the organization of power matters in the European Union as well as the energy markets are discussed in this Keynote Paper. The Council of European Energy Regulators is introduced. The goal of the European Union regarding energy generation and consumption in the future are analyzed. (R.P.)

  6. Information Guide: regionalism and separatism in the European Union

    OpenAIRE

    EDC, Cardiff

    2013-01-01

    A brief bibliography of information sources about current issues of regionalism and separatism in the European Union with a particular focus on Catalonia, Flanders and Scotland. This guide was compiled in connection with the event Regionalism and Separatism in the European Union held in the Cardiff EDC on 21 February 2013.

  7. The causal texture of trade union environments | Iyayi | Global ...

    African Journals Online (AJOL)

    This paper is an attempt to fill an important gap in the existing literature on trade unions by providing a more adequate theoretical formulation of trade union environments. The discussion suggests that unlike the environment of business and related organisations whose causal texture is understood in terms of uncertainty, ...

  8. The Banking Union: An Overview and Open Issues

    NARCIS (Netherlands)

    D. Schoenmaker (Dirk)

    2016-01-01

    markdownabstractThe move to European Banking Union involving the supervision and resolution of banks at euro-area level was stimulated by the sovereign debt crisis in the euro area in 2012. However, the long-term objective of Banking Union is dealing with intensified cross-border banking. The

  9. THE INTERFERENCE OF EUROPEAN UNION LAW WITH PUBLIC INTERNATIONAL LAW

    Directory of Open Access Journals (Sweden)

    ROXANA-MARIANA POPESCU

    2011-04-01

    Full Text Available The European Union Law is an unique legal phenomenon developed in the process of European integration within the framework of the European Communities and the European Union; a result of the implementation of the supranational authority of the European institutions. The European Union law is a specific legal system having independent sources and principles that developed at the border-line of international law and domestic law of the EU’s Member States. The authonomy of the European Union law is affirmed by a case-law of the Court of Justice of the European Union.The European Union has its own legal order which is separate from international law and forms an integral part of the legal systems of the Member States. The legal order of the Union is founded on various different sources of law. The different nature of these sources has imposed a hierarchy among them. At the pinnacle of this hierarchy we find primary law, represented by the Treaties and general legal principles, followed by international treaties concluded by the Union and secondary law founded on the Treaties.

  10. 32 CFR 231.8 - Procedures-overseas credit unions.

    Science.gov (United States)

    2010-07-01

    ... geographic franchise. (2) The extension of credit union service overseas is encouraged consistent with the... geographic franchise with a specific field of membership, the Secretary of the Military Department (or... geographic franchises assigned to credit unions serving DoD overseas installations. (ii) Where there is no Do...

  11. Students' Unions, Consumerism and the Neo-Liberal University

    Science.gov (United States)

    Brooks, Rachel; Byford, Kate; Sela, Katherine

    2016-01-01

    This article explores the economic relationships between individual students' unions and their wider institutions, and the ways in which they articulate with a pervasive consumerist agenda across the higher education sector. We draw on data from a UK-wide study to argue that students' unions have an ambivalent relationship with consumerist…

  12. Worker-Centered Learning: A Union Guide to Workplace Literacy.

    Science.gov (United States)

    Sarmiento, Anthony R.; Kay, Ann

    This guide examines organized labor's views on adult literacy. It also describes several union-sponsored workplace education programs and suggests how a union can plan and operate a worker-centered literacy program. The book is organized in three parts. The first part examines workplace literacy in four chapters that cover the following: the…

  13. Faculty Unions, Business Models, and the Academy's Future

    Science.gov (United States)

    Rhoades, Gary

    2011-01-01

    In this article, the author addresses questions about the future of faculty unions, business models, and the academy by providing some current and historical context regarding the causes of and conflicts about faculty unions. He also reviews trends in college and university management over the past three decades, using California, Ohio, and…

  14. 75 FR 80678 - Conversions of Insured Credit Unions

    Science.gov (United States)

    2010-12-23

    ... final rule with request for comments. SUMMARY: NCUA is issuing final amendments to revise the definition... Credit Union Share Insurance Fund (NCUSIF) share insurance to nonfederal share insurance in 12 CFR part...-credit union mergers and terminations of NCUSIF share insurance and conversions from NCUSIF share...

  15. A brief overview of the Civil Union Act* | Ntlama | Potchefstroom ...

    African Journals Online (AJOL)

    ... same-sex couples as envisaged in the Act, and not to an analysis of the nature of the institution of marriage itself or the theological and social dimensions of same-sex marriages. Keywords: same-sex marriages; civil union; equality; constitutional rights; constitutional protection of homosexual relationships; Civil Union Act ...

  16. Trade unions and social movements: methods and forms of interaction

    Directory of Open Access Journals (Sweden)

    O. L. Tupytsia

    2017-07-01

    New typological features of social movements are formed on the basis of a new type of social and communication links. Social hierarchy and class antagonisms, which provided the basis for the existence and development of trade unions in the past, expired. Therefore, the organizational forms of trade unions as social movements have become more available and acceptable for contemporary citizens.

  17. Regulatory Regionalism and Education: The European Union in Central Asia

    Science.gov (United States)

    Jones, Peter

    2010-01-01

    This paper investigates the purchase which Jayasuriya's regulatory regionalism approach offers for an analysis of the European Union's engagement in Central Asia. The European Union has a clearly articulated strategy through which to pursue what it sees as its interests in Central Asia and the development of a range of EU-Central Asia education…

  18. 12 CFR 704.3 - Corporate credit union capital.

    Science.gov (United States)

    2010-01-01

    ... minimum level of required capital and NEV ratios after the funds are called. (4) Liquidation. In the event...) Capital ratio. A corporate credit union will maintain a minimum capital ratio of 4 percent, except as otherwise provided in this part. A corporate credit union must calculate its capital ratio at least monthly...

  19. Monetary union without fiscal coordination may discipline policymakers

    NARCIS (Netherlands)

    Beetsma, R.M.W.J.; Bovenberg, A.L.

    1995-01-01

    We show that, with benevolent policymakers and fiscal leadership, monetary unification reduces inflation, taxes and public spending. These disciplining effects of a monetary union, which rise with the number of fiscal players in the union, are likely to raise welfare. Joining an optimally designed

  20. IMPORTANCE OF THE EUROPEAN BANKING UNION NEW DIRECTIVES

    Directory of Open Access Journals (Sweden)

    MEDAR LUCIAN-ION

    2014-10-01

    Full Text Available European Banking Union has set new rules on monetary market especially for credit institutions and for financial banking groups in general. Economic and monetary union requires accomplishment of political and monetary union and democratic control of the European institutions on a single financial market. In this respect through its management organisms, EU has designed a series of unique mechanisms of financial union and called for a fiscal union. Union of European financial market is possible through a new regulation of the markets. In this project, monetary union of the EU member countries is possible by implementing single mechanism of supervision (Single Supervisory Mechanism and single mechanism of resolution (Single Resolution Mechanism. European Banking Union may be made by monitoring of a single banking supervisor based on a common system for managing and resolving banking crises and a uniform system of protecting people's savings. Romania opted for these unique mechanisms of macro-prudential supervision of the financial system. And by performing the real convergence criteria of integration, Romania will have all conditions of integration in the ,,euro area,,.

  1. MILITARY TRADE UNIONS: A THREAT TO NATIONAL SECURITY ...

    African Journals Online (AJOL)

    sacrificed at the altar of soldiers' constitutional rights to form and join trade unions .... includes a rights-based culture, a rise in individualism, a change in the acceptance of ... military leadership with the military unions that poses the greatest threat to civil– ... 10 European Organisation of Military Associations, available at ...

  2. Expert advice and political choice in constructing European banking union

    NARCIS (Netherlands)

    Donnelly, Shawn

    2016-01-01

    International actors promoted the transfer of regulatory authority and financial resources from national governments to the European Union (EU) in the context of establishing the prerequisites for financial stability in Europe through banking union. It was supplied, however, by a political process

  3. Dimethylhydrazine model is not appropriate for evaluating effect of ethanol on colorectal cancer El modelo de la dimetilhidrazina no sirve para evaluar el efecto del etanol sobre el cáncer colorrectal

    Directory of Open Access Journals (Sweden)

    M. Perše

    2007-08-01

    Full Text Available 1,2 dimethylhydrazine (DMH rat model has been proven to be a valuable animal model of colorectal cancer. Because of its morphological similarity to human colorectal cancer, DMH rat model was used to produce information in histology and biochemistry of tumours development as well as on factors that retard or enhance tumorigenesis. Nevertheless, it has been shown that DMH model has limitations, which raise the question, whether experiments evaluating effect of ethanol on DMH model are ethically justified. In this paper authors summarize experimental results evaluating effect of ethanol consumption on DMH rat model with aim to prevent unnecessary duplication of animal experimentation or execution of ethically unjustified animal experiments in the future and to warn scientists that results from studies evaluating ethanol on DMH rat model can not be generalized to humans.Se ha observado que el modelo de la 1,2-dimetilhidrazina (DMH en la rata es un valioso modelo animal de cáncer colorrectal. Debido a su parecido morfológico con el cáncer colorrectal humano, el modelo de la DMH en la rata se ha empleado para conseguir información acerca de la histología y la bioquímica del desarrollo tumoral, además de sobre los factores que retrasan o potencian la tumorigénesis. No obstante, se ha visto que el modelo de la DMH tiene sus limitaciones, lo que lleva a preguntarse si están justificados, desde el punto de vista ético, los experimentos que evalúan el efecto del etanol sobre este modelo. En este documento, los autores resumen los resultados experimentales que evalúan el efecto del consumo de etanol sobre el modelo de la DMH en la rata con el fin de evitar la duplicación innecesaria de la experimentación animal o la ejecución de experimentos con animales sin justificación ética en el futuro, además de avisar a los científicos de que los resultados obtenidos de los estudios que han evaluado el etanol con el modelo de la DMH en la rata no

  4. O processo de adoecer do portador de colostomia por câncer El proceso de la enfermedad del portador de colostomía por cáncer The sickening process of colostomy patients by cancer

    Directory of Open Access Journals (Sweden)

    Sônia Ayako Tao Maruyama

    2005-04-01

    Full Text Available Compreender como os portadores de colostomia por câncer e seus familiares percebem o processo do adoecer é o objetivo deste estudo. Os referenciais teóricos e metodológicos que fundamentaram o estudo foram a antropologia interpretativa, a antropologia médica e a etnografia. Os dados foram obtidos por meio de entrevistas, sob a forma de narrativas, e observações junto a doze portadores de colostomia e cinco familiares, no período de junho de 2002 a maio de 2003. Da análise dos dados identificamos a categoria: A vida antes da colostomia por câncer. Os dados permitiram compreender que a experiência de ter uma colostomia por câncer é uma construção sociocultural.La finalidad de este estudio fue comprender como los portadores de colostomía por cáncer y sus familiares perciben el proceso de la enfermedad. Los referenciales teóricos y metodológicos que fundamentaron el estudio fueron: la antropología interpretativa, la antropología médica y la etnografía. Los datos fueron obtenidos por medio de entrevistas, en forma de narrativas, y observaciones de doce pacientes de colostomía y cinco familiares, en el período de Junio del 2002 a Mayo del 2003. Del análisis de los datos identificamos la categoría: la vida antes de la colostomía por cáncer. Los datos permitieron comprender que la experiencia de tener una colostomía por cáncer es una construcción socio-cultural.This study aimed to understand how patients with colostomy by cancer and their family members perceive the sickening process. The theoretical and methodological reference frameworks the study was based on were anthropology and ethnography. Data were collected through interviews, in a narrative form, and observations with twelve colostomy patients and five family members, in the period from June 2002 to May 2003. The analysis allowed us to understand that the experience of having a colostomy by cancer is a social-cultural construction.

  5. JPRS Report, Soviet Union, International Affairs.

    Science.gov (United States)

    1987-06-26

    Visita del presidente de la Republica de Colombia Belisario Betancur a los Estados Unidos: abril, 1985. S. 1., s.a., pp 370, 372. 19. EL ESPECTADOR...Process, Origin of ’Rio de Janeiro Group’ Described (Editorial; LATINSKAYA AMERIKA, No 3, Mar 87) 25 Course of U.S.-Colombia Relations Analyzed...not translated] 39 REPORTS Yu.F. Pogorelov. Science at the Service of Agriculture in Mexico 46 [not translated] MEETINGS, INTERVIEWS The Concerns

  6. Analysis of Abdi Kerta Rahardja Union Health Assesment

    Directory of Open Access Journals (Sweden)

    Indo Yama Nasarudin

    2016-10-01

    Full Text Available This study aims to identify and analyse the health assessment union of Abdi Kerta Raharja. Health assessment used measurement and calculation in Rule Deputy Control of Ministry of Union and SMEs of the Republic of Indonesia Number 6 Year 2016. Aspects for health assessment consists the capital aspect, productive asset quality aspects, management aspects, aspects of efficiency, liquidity aspect, the aspect of self-reliance and growth and aspects of the identity of union. Based on the results obtained value for all aspects of health assessment union of Abdi Raharja Kerta is 81.00. It can be concluded that the union of Abdi Kerta Raharja have a healthy category for health assessmentDOI: 10.15408/etk.v15i2.3865

  7. UNION-K 2.0 User's Manual

    International Nuclear Information System (INIS)

    Yoo, Jae Woon; Jang, Jin Wook; Kim, Yeong Il

    2008-12-01

    The unified Input/Output processor UNION-K(UNified Input/Output Processor for Neutronics Analysis by K-CORE) has been developed to provide the automatic input file generation and output processing for the fast reactor core analysis. UNION-K includes the material database for reactor analysis and produces the input files for effective cross section generation, core analysis, and reactivity coefficient calculations. UNION-K can execute corresponding core analysis module and edit core performance parameters from the outputs. UNION-K also provides the graphical interface to check the geometrical arrangement of core and fuel sub-assembly and produces the picture files that can be used for reporting. This report has been prepared for instruction of using UNION-K Ver. 2.0 with examples

  8. Influencia de la transferencia en la resistencia y dureza de las uniones soldadas obtenidas por el proceso de soldadura GMAW

    Directory of Open Access Journals (Sweden)

    Sandra Patricia Romero Nieto

    2013-04-01

    Full Text Available Este trabajo describe el comportamiento del proceso de soldadura GMAW con alambre compuesto de núcleo metálico, en uniones soldadas de acero ASTM A131, grado AH 32, utilizando dos composiciones de gas de protección y las transferencias de arco pulsado y corto circuito. Las propiedades mecánicas y la microestructura se evaluaron y los resultados indican que se logra mayor resistencia a la tensión y, a su vez, un perfil de dureza más homogéneo utilizando la transferencia de arco pulsado. Asimismo, se establece que la porosidad en el pie de soldadura de las uniones en T con depósito en filete se relaciona con la longitud de arco.

  9. Itinerário percorrido pelas mulheres na descoberta do câncer Camino recorrido por las mujeres en la descubierta del cáncer The journey experienced by women through a cancer diagnosis

    Directory of Open Access Journals (Sweden)

    Maria Aparecida Salci

    2009-09-01

    Full Text Available Este estudo se propõe a desvelar o itinerário vivenciado pelas mulheres no processo de descoberta do diagnóstico de câncer. Como estratégia teórico-metodológica, foram utilizados o Interacionismo Simbólico e a Grounded Theory. Foram informantes do estudo 20 indivíduos 10 mulheres portadoras de câncer e seus respectivos familiares significantes. Os resultados mostram desde o momento em que elas vivenciam as primeiras percepções sobre a alteração fisiológica em seu corpo, passando pela busca de ajuda profissional, até o recebimento do diagnóstico de câncer. O itinerário apresentado permite conhecer aspectos da realidade experienciada anteriormente ao recebimento do diagnóstico e ressalta a importância de os profissionais valorizarem mais as queixas das pessoas que os procuram, percebendo que se esta procura aconteceu é porque a pessoa está preocupada. Esta atitude pode favorecer a identificação precoce do problema e, por conseguinte, garantir melhor prognóstico e qualidade de vida.Este estudio propone revelar el camino vivido por las mujeres en el proceso de descubierta del diagnóstico de cáncer. Como estrategia teórico-metodológica fueron utilizados el Interaccionismo Simbólico y la Grounded Theory. Fueron investigados durante el estudio 20 individuos 10 mujeres portadoras de cáncer y sus respectivos familiares próximos. Los resultados muestran desde el momento en que ellas notan las primeras diferencias sobre la alteración fisiológica en su cuerpo, pasando por la búsqueda de ayuda profesional hasta el recibimiento del diagnóstico de cáncer. El camino presentado permite conocer aspectos de la realidad vivida anteriormente al recibimiento del diagnóstico y resalta la importancia de que los profesionales valoren más las quejas de las personas que los buscan, percibiendo que si esta búsqueda ocurrió es porque la persona está preocupada. Esta actitud puede facilitar la identificación precoz del problema y

  10. Cutaneous manifestations of breast cancer

    OpenAIRE

    Agnieszka B. Owczarczyk-Saczonek; Dawid Sigorski; Paweł Różanowski; Agnieszka Markiewicz; Waldemar J. Placek

    2017-01-01

    Breast cancer is the most common malignant neoplasm among women in Poland and in the European Union. According to most recent data of the Polish National Cancer Registry, in 2014 breast cancer was diagnosed in over 17,000 women. Based on the National Health Fund records, it is estimated that there are about 55,000–60,000 women in Poland who have a history of breast cancer diagnosis and are potentially at a risk of relapse. The most common sign of breast cancer is the presence of a nodule, how...

  11. The role of 3D Helical CT in the reconstructive treatment of maxillofacial cancers; Tomografia Computerizzata spirale con elaborazioni tridimensionali di superficie nel trattamento ricostruttivo dei tumori maligni del massiccio facciale

    Energy Technology Data Exchange (ETDEWEB)

    De Rosa, V.; Ziviello, M. [Ospedale Cardarelli, Servizio di Radiodiagnostica, Naples (Italy); Ionna, F.; Mozzillo, N. [Ospedale Cardarelli, Div. di Chirurgia B, Ist. Nazionale Tumori Fondazione G. Pascale, Naples (Italy); Parascandolo, S. [Ospedale Cardarelli, Div. di Chirurgia Maxillo-Facciale, Naples (Italy)

    2000-12-01

    -ferrous metal of low atomic number that allows very clear CT and MR images to be obtained. Further Ti features are strength, biocompatibility and easy handling. 3D Helical CT scan has proven to be the most complete and accurate imaging technique for reconstructive plastic surgery with alloplastic material in advanced maxillofacial cancer, also considering the anatomic and functional complexity of his area. The prospect is provided to identify virtual 3D presurgical ablation planes. These may allow the surgeon to improve plastic reconstruction and shorten intervention time. [Italian] Scopo di questo articolo e' quello di analizzare il ruolo della TC spirale e i vantaggi delle ricostruzioni tridimensionali di superficie nella pianificazione e controllo degli interventi di chirurgia ricostruttiva plastica con materiale alloplastico nelle neoplasie maligne del massiccio facciale. Sono state eseguite dal 1996 al 1999 11 ricostruzioni plastiche dell'osso mascellare per neoplasie osteodestruenti il massiccio facciale utilizzando materiale alloplastico. Per la ricostruzione della parete anteriore dell'osso mascellare e del pavimento orbitario e' stata utlizzata una rete di titanio al 100% modulabile. Applicato nel cavo residuo dell'osso un otturatore siliconato sormontante una protesi acrilica con arcata dentaria per la ricostruzione del palato. In due casi utilizzato pericardio bovino modulato sulla soluzione di continuo. Tutti i pazienti sono stati studiati con TC spirale sia nella fase preoperatoria che entro il sesto mese dall'intervento chirurgico. Elaborate ricostruzioni tridimensionali della superficie (shaed surface display-SSD) con valori soglia compresi tra 425 e 630 UH ma con intervallo piu' stretto di finestra sui valori UH all'interfaccia osso/rete di titanio nei controlli del modellamento protesico. L'elaborazione tridimensionale della superificie sui dati ottenuti con acquisizione volumetrica ha fornito in tutti casi la fedele

  12. [Prevalence of breast cancer sub-types by immunohistochemistry in patients in the Regional General Hospital 72, Instituto Mexicano del Seguro Social].

    Science.gov (United States)

    Pérez-Rodríguez, Gabriel

    2015-01-01

    Breast cancer mortality has increased in women 25 years and over, and since 2006 it has surpassed cervical cancer. Breast cancer is a heterogeneous disease, with several clinical and histological presentations that require a thorough study of all clinical and pathological parameters, including immunohistochemistry to classify it into subtypes, have a better prognosis, provide individualised treatment, increase survival, and reduce mortality. To evaluate the prevalence of sub-types of breast cancer and the association with the clinical and histopathological features of the tumour. An observational, retrospective, cross-sectional and analytical study conducted on 1380 patients with a diagnosis of breast cancer have been classified by immunohistochemistry into four subtypes: luminal A, triple negative, luminal B and HER2. An analysis was performed on the association with age, risk factors, and the clinical and histopathological features of the tumour. The mean age of the patients was 53.3 ± 11.4. The frequency was luminal A (65%), triple negative (14%), luminal B (12%), and HER2 (9%). The most frequent characteristics were the 50 to 59 age range, late menopause, the right side, upper external quadrant, stage II, metastatic lymph nodes, and mastectomy. The most frequent sub-type was luminal A, and together with the luminal B are those which have better prognosis compared with the triple negative and HER2. Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.

  13. Diagnóstico y tratamiento quirúrgico del cáncer de tiroides en el Centro de Investigaciones Medicoquirúrgicas (CIMEQ Diagnosis and surgical treatment of thyroid cancer in the Centre for Medicosurgical Research

    Directory of Open Access Journals (Sweden)

    C. Julio Díaz Mesa

    2008-03-01

    Full Text Available INTRODUCCIÓN. El carcinoma de tiroides es infrecuente, pero en cambio constituye la neoplasia maligna más común del sistema endocrino. Fueron objetivos de esta presentación describir los resultados del diagnóstico y tratamiento del cáncer de tiroides durante un quinquenio, en el Centro de Investigaciones Medicoquirúrgicas, caracterizar diversas variables de la población afectada y determinar la relación entre técnica quirúrgica realizada e índice pronóstico a partir de la edad, metástasis a distancia, extensión de la enfermedad y tamaño del tumor (AGES. MÉTODOS. Se realizó un estudio observacional, descriptivo y prospectivo con elementos analíticos incorporados, de 52 pacientes operados de cáncer de tiroides en el CIMEQ, entre enero de 2001 y diciembre de 2005. Se aplicó el índice pronóstico AGES para los pacientes con cáncer de tiroides bien diferenciado y se relacionó con la técnica quirúrgica empleada. RESULTADOS. El cáncer de tiroides predominó en el sexo femenino (86,5 % en las edades entre 29 y 67 años, y en el hombre por encima de los 55 años. La biopsia por aspiración con aguja fina resultó un procedimiento de utilidad en el diagnóstico del cáncer de tiroides, con una alta concordancia con los diagnósticos por congelación y parafina. El carcinoma papilar resultó el más frecuente (71,2 % y la lesión más asociada, la tiroiditis de Hashimoto. Predominó la cirugía radical en pacientes que requerían cirugía conservadora según el índice pronóstico AGES. Las complicaciones se asociaron a la cirugía radical. CONCLUSIONES. El cáncer de tiroides resulta más frecuente en las mujeres de mediana edad. La biopsia por aspiración con aguja fina cobra valor a la hora de plantear la técnica quirúrgica, teniendo en cuenta el alto índice de concordancia con la biopsia por parafina. El índice pronóstico AGES no siempre fue tomado en cuenta a la hora de elegir la técnica quirúrgica, de ahí que

  14. Differentiated thyroid cancer: reclassification of the risk of recurrence based on the response to initial treatment; Carcinoma diferenciado de tiroides: reclasificación del riesgo de recurrencia según la respuesta al tratamiento inicial

    Energy Technology Data Exchange (ETDEWEB)

    Martínez, M. P.; Lozano Bullrich, M. P.; Rey, M.; Ridruejo, M. C.; Bomarito, M. J.; Claus Hermberg, H.; Pozzo, M.J., E-mail: mpazmartinez@yahoo.com [Hospital Alemán, Servicio de Endocrinología, Buenos Aires (Argentina)

    2014-07-01

    response was observed in 11 (84.6 %) and an acceptable response was observed in 2 (15.4 %) of the intermediate-risk classified patients and in the high-risk group 1 patient (100 %) presented an acceptable response. Clinical status of patients after 2 years of IT: 25 (80.6 %) with no evidence of disease (NED), 6 (19.4 %) with biochemical persistence (BP) and 0 (0 %) with structural persistence (EP), recurrence (R) or death (D). After a mean long-term follow-up period of 51.3 months, the clinical status was: 25 (80.6 %) with NED, 4 (12.9 %) with BP and (0 %) with EP, R or D; for the remaining 2 (6.5 %) no long-term follow-up data was available (ND). At the end of the long-term follow-up period, 24 (96 %) patients with excellent response after 2 years of IT remained NED, whereas 1 (4 %) was reported as ND and 1 (16.7 %) patient with acceptable response after 2 years of IT remained NED (initially this was a low-risk patient), 4 (66.6 %) remained BP, 1 (16.7 %) was reported as ND and no EP, R or D was observed. Conclusions: 1) reclassification of patients was particularly useful in the intermediate risk group because 84.6 % of these patients had an excellent response after two years of IT, 2) reclassification of patients based on the response to IT, allows us to optimize their follow-up and 3) although the mean long-term follow-up period was 51.3 months, there was a good correlation between clinical status after two years of IT and after the long-term follow-up period, mainly in the excellent response group. (authors) [Spanish] Introducción: la clasificación de la American Thyroid Association (ATA) para carcinoma diferenciado de tiroides (CDT) aporta una visión estática del paciente al inicio y no está diseñada para ser modificada. El Memorial Sloan-Kettering Cancer Center (MS-KCC) diseñó una reclasificación a 2 años del tratamiento inicial (TI), permitiendo tener una óptica más dinámica. Objetivo: comunicar nuestra experiencia con la reclasificación del riesgo de

  15. When strong unions meet precarious migrants: Building trustful relations to unionise labour migrants in a high union-density setting

    DEFF Research Database (Denmark)

    Refslund, Bjarke

    2018-01-01

    Based on case studies in a fish processing plant and a demolition company, this article shows how strong and institutionally embedded unions interact with migrant workers in a precarious labour market position in order to safeguard their working conditions and organise them. It shows how strong...... in the IR-model. The dynamic relation between migrant workers and national unions in this high-density setting is discussed emphasising the need for building a trustful relation between the migrant workers and the unions in order to empower the migrants to better navigate in the national labour market...... unions are in a good position to include migrant workers and thereby resist labour market segmentation. The strong Danish unions, faced with the serious challenges of intra-European labour migration, have increased their attention and resources devoted to organising migrant workers and including them...

  16. Vírus HPV e câncer de colo de útero Virus HPV y el cáncer del cuello uterino Human Papillomavirus (HPV and uterine cervical cancer

    Directory of Open Access Journals (Sweden)

    Janete Tamani Tomiyoshi Nakagawa

    2010-04-01

    Full Text Available Este artigo refere-se a uma revisão de literatura sobre o vírus HPV e câncer de colo de útero, com o objetivo de levantar aspectos da infecção do vírus que influenciam no curso natural do câncer de colo de útero tais como: a tipologia do vírus, a duração e a persistência da infecção além de associar com as manifestações das lesões precursoras até a evolução da neoplasia. Foi possível constatar a forte associação da infecção com a evolução da neoplasia cervical, no entanto, ainda são necessários estudos que elucidem melhor certos aspectos da infecção do vírus HPV que agem sobre o colo do útero para que as ações de prevenção e combate a doença sejam mais eficazes.Este artículo se refiere a una revisión de literatura sobre el virus HPV y la neoplasia cervical, con el objetivo de levantar aspectos de la infección del virus que influye en el curso natural del cáncer de cuello del útero tales como: la tipologia del virus, la duración y la persistencia de la infección además de asociarlo a las manifestaciones de las lesiones precursoras hasta la evolución de la neoplasia. Ha sido posible constatar la fuerte asosiación de la infección con la evolución de la neoplasia cervical, entretanto, aún son necesarios estudios que eluciden mejor ciertos aspectos de la infección del virus HPV que actúa sobre el cuello del útero para que las acciones de prevención y combate a la enfermedad sean más eficaces.This article refers to a review of literature about the HPV virus and the cervical neoplasia, aiming at raising aspects of the virus infection which influences in the natural development of the uterine cervical cancer such as: the type of virus, the duration and the persistence of the infection and also the association with the manifestations of the preceding lesions up to the evolution of the neoplasia. It was possible to notice the strong association of the infection with the evolution of the cervical

  17. Socioeconomic determinants of cervical cancer screening in Latin America Determinantes socioeconómicos de las pruebas de detección sistemática del cáncer cervicouterino en América Latina

    Directory of Open Access Journals (Sweden)

    Samir Soneji

    2013-03-01

    Full Text Available OBJECTIVE: To assess the impact of health care access and socioeconomic determinants on Pap smear screening in Latin America. METHODS: Individual-level data was collected from the Demographic and Health Surveys in Bolivia, Brazil, Dominican Republic, Ecuador, Guatemala, Nicaragua, Peru, and Trinidad and Tobago between 1987 and 2008. Multivariate logistic regression analyses were used to identify socioeconomic and health care determinants of two outcomes: knowledge of Pap smears and recent Pap smear screening. RESULTS: In all countries, the proportion of women with a recent Pap smear screening remained below 55%. Key determinants of knowledge of Pap smears were age, education, and recent doctor's visit. For recent Pap smear screening, key determinants were wealth and recent doctor's visit. Women were between 1.47 and 3.44 times more likely to have received a recent Pap smear if they had a recent doctor's visit. Even the poorest women with a recent doctor's visit were more likely to screen than the richest women without a recent visit. CONCLUSIONS: These data suggest that visiting a doctor is an important determinant of cervical cancer screening in Latin America. Because screening may coincide with other medical visits, physicians could effectively encourage screening.OBJETIVO: Evaluar las repercusiones del acceso a la atención de salud y de los determinantes socioeconómicos sobre la detección sistemática del cáncer cervicouterino con la prueba de Papanicolaou en América Latina. MÉTODOS: Se recopilaron datos individuales a partir de Encuestas de Demografía y Salud realizadas en Bolivia, Brasil, Ecuador, Guatemala, Nicaragua, Perú, República Dominicana y Trinidad y Tobago entre 1987 y 2008. Se utilizaron análisis de regresión logística con múltiples variables para identificar los determinantes socioeconómicos y de atención de salud de dos resultados: el conocimiento de la existencia de la prueba de Papanicolaou y el tamizaje

  18. French electricity union, 2009 annual report

    International Nuclear Information System (INIS)

    2010-05-01

    The Union Francaise de l'Electricite (UFE - French Electricity Union), an association governed by the law of 1901, created in May 2000, is the professional association for the electricity sector. It represents the sector's employers within the electricity and gas industries branch and promotes the interests of its members, producers, system operators or electricity suppliers, in both economic and industrial areas. Directly or indirectly, the UFE includes more than 500 companies that employ more than 150, 000 people in France, with a sales figure of more than euro 40 billion. This report summarises the 2009 key events and figures and the activities of the different committees and working groups: the Sustainable Electricity Club, the General Economy Committee, the Social Committee of Employers' Groups, the Generation Committee, the Hydroelectricity Working Group, the Markets Committee, the Systems and Public Service Committee, and the European Affairs Committee. The year 2009 was marked by the effects of the international crisis that affected all of the economic workings of all of the world's countries. In an attempt to deal with its consequences, each state prepared a recovery plan and implemented austerity measures. For its part, France is relying on its Great Loan in order to re-invigorate the sectors that are likely to be the drivers of the recovery and of a new rapid expansion of industry. The electricity sector has essential strengths, notably one of the least carbon-producing production stocks in Europe, and it also ensures that France has energy security and independence. In 2009, the UFE devoted itself to demonstrating the central role that electricity can play in the struggle against the emission of greenhouse gases. However, France must now concentrate its efforts on setting up a true energy policy that consolidates its carbon competitive advantage. This clearly means a framework that encourages crucial investments in industrial infrastructures: basic and

  19. Inspección visual con ácido acético (IVAA) en la detección precoz del cancer de cuello uterino :

    OpenAIRE

    Foresi, Ana María del Valle

    2009-01-01

    Tesis Doctor en Medicina y Cirugía -- Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. La Inspección Visual con Acido Acético (IVAA) constituye una alternativa frente a la citología Exfoliativa en el examen de detección del cuello de útero en lugares de escasos recursos o como complemento de papanicolaou en zonas de mediano recursos. OBJETIVOS: Examinar la sensibilidad, especiaficidad, valor predictivo positivo y negativo de los tres métodos de pesquisa (inspección visual con...

  20. Advances of the Surgery of the Breast Cancer with help of the Nuclear Medicine; Avances de la cirugia del cancer de mama con la colaboracion de la medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Sierra Garcia, A.; Gomez Embuena, D. A.

    2009-07-01

    The incorporation of the nuclear medicine to the surgical current practice In the treatment of the cancer of breast, by means of the application of radioactive isotopes, have supposed a great achievement not only in the surgical and predicted results but also in the surgical skills more effective and less aggressive. The systematic research of the marking and extirpation of Sentinel Lymph Node is avoiding in the early cancer the linfadenectomy axilar. The application of the ROLL and SNOLL skills is being determinant in the extirpation with trustworthy margins of the non-palpable lesions cancer, with big safety instead harpoons that we used before. (Author) 6 refs.

  1. Catálogos colectivos: ¿reales o virtuales? Una revisión de la literatura = Union catalogs: real or virtual ones? A literature review

    OpenAIRE

    Graciela Spedalieri

    2002-01-01

    Revisión de la literatura sobre catálogos colectivos publicada en los últimos cinco años. Los desarrollos en el área de búsqueda distribuida han dado lugar a la creación de catálogos colectivos virtuales. Se analizan las características del modelo tradicional y las del modelo virtual, comparando las ventajas y desventajas de cada uno.Review of the literature on union catalogs published during the last five years. Developments in the area of distributed search gave place to the creation of vir...

  2. Photovoltaic remuneration policies in the European Union

    International Nuclear Information System (INIS)

    Sarasa-Maestro, Carlos J.; Dufo-López, Rodolfo; Bernal-Agustín, José L.

    2013-01-01

    The purpose of this paper is to study the development of photovoltaic (PV) systems in some countries of the European Union (EU). We establish the stage of development of each country, their short- and long-term degree of compliance and the trends of international investors favouring one market or another. EU countries employ four major types of programs to encourage PV use: (1) feed in tariffs (FIT), (2) green certificates with a quota system, (3) investment and tax incentives, and (4) bids on the quota system. The FIT is the most widely used program to create incentives for the use of PV systems. During the past two years, PV tariffs have been reduced in many European countries. Investments in PV are still attractive, in some cases even overly generous with respect to the financial landscape in the world. This paper shows, for each country, the type of incentive and the trends in and forecast for installed capacity and calculates the internal rate of return (IRR) for investment in grid-connected PV systems. - Highlights: ► This work shows the EU positioning on development of photovoltaic (PV) systems. ► The installed power and the internal rate of return have been used as reference. ► The existing programs in relation to pay and incentives have been reviewed

  3. Transitional Democracy, Legitimacy and the European Union

    Directory of Open Access Journals (Sweden)

    Patricia Kaplánová

    2015-03-01

    Full Text Available Nowadays the ongoing global crisis has triggered an issue how to set up a theoretical framework of global governance. The integration to a supranational level of governance has been a contemporary process of democratization in recent decades. To analyze the institutionalization of global governance means to recognize a normative idea of democracy. The theory of international relations demonstrates that there are four normative models of democracy at the supranational level of governance. In my opinion, a crucial difference of the institutionalization is a concept of legitimacy of global democratic regime. Because of a divided understanding of legitimacy at the transnational level of governance is difficult to find a consensus in which way should be a transnational democracy framed. A dual legitimacy in a supranational organization like the European Union also triggers a specific democratic deficit. My point of view corresponds with the division of transnational orders in normative way and its correspondence to legitimacy. Cla rifying the duality of legitimacy can help us not only to solve all globalizing problems but of course to decide in which way we want to make the supranational organizations work.

  4. The European Union and its Neighbours:

    Directory of Open Access Journals (Sweden)

    Alberto Chilosi

    2007-06-01

    Full Text Available The paper considers the status of the European Neighbourhood Policy in the light of the new Financial Perspective 2007-2013 and of the present internal state of the European Union. Even if in theory the ENP could have been a valid substitute for enlargement, it does not seem to have reached its aim of providing an adequate surrogate for full membership. Considering the figures of the new Financial Perspective 2007-2013, the issue of market access, and the internal power dynamics of the EU, we see that it is hardly conceivable that the ENP could ever give to its neighbours the same economic advantages that membership gives to the poorer members of the EU. Another controversial aspect is the clear asymmetric nature of the ENP, whereby the payoff for neighbours is conditioned on their “good behaviour”, thus amounting to a form of soft imperialism. While ENP tries to establish a comprehensive and coherent framework of the EU’s relations with its neighbourhood, the actual behaviour of EU towards its neighbours is shown to present some inconsistences due to political expedience and pragmatic concerns. The consideration of some related basic issues of EU institutional reform, such as the weakening of the powers of the member states, or the introduction of some intermediate forms of partial membership, concludes the paper.

  5. Winston Churchill And The European Union

    Directory of Open Access Journals (Sweden)

    Troitiño David Ramiro

    2015-06-01

    Full Text Available Given Winston Churchill’s influence and achievement as a writer, historian, adventurer, soldier, artist, and politician, his participation in the European integration process is crucial to understanding the entire scope of the project in its origins. Churchill was a fundamental voice promoting the Franco-British Union, a promoter of the European Communities, and an active participant of the Congress of Europe, embryo of the Council of Europe. This article analyzes Churchill’s view of European integration through his political speeches, in particular those delivered in Zurich and in The Hague, his ideas about the League of Nations and the United Nations, his understanding of the British Empire, and the special relations between the UK and the USA. His participation in the process of uniting Europe in its early stages provides us with essential information about the original plans for the creation of a united Europe and understanding the traditional British approach to the EU, including the current position of the conservative government led by Cameron.

  6. Ethnicity and Power in the Soviet Union

    Directory of Open Access Journals (Sweden)

    Andrzej Wierzbicki

    2017-01-01

    Full Text Available Twenty years have passed since the dissolution of the Soviet Union. Up until the point of dissolution, the Soviet authorities and intellectual elite had attempted to build a community in order to unite all Soviet citizens in the spirit of socialist modernisation. Although it is difficult to demonstrate that ‘a Soviet nation’ was successfully created [1], the attempt to build such a nation can serve as a case study through which to examine nation-building processes for constructivists as well as modernists . In addition to socialist modernisation, the Soviet nation aimed to be identified as a state, which would make it similar to the political nations dominant in western countries. Contrary to western tradition, however, it was not a nation state that provided full rights for all its citizens, but rather a socialist state that was ‘ruled by workers and peasantry’. Nevertheless, the authorities aimed to give the Soviet nation the characteristics of a specific nation state. “It was a nation that in historical terms strived, or more accurately part of which strived, to form or proclaim a particular state” [2]. While at the time of proclaiming the USSR there was no such thing as the Soviet nation, it can be assumed that it was intended to become a constructed titular nation. The majority of national communities, even created ones, have an ethnic core. However academics cannot agree on the kind of state the USSR was, to what extent it took into account the ethnicity of its multinational population, how much it reflected the values, culture, and interests of its largest population group (i.e., the Russians or even whether it was a Russian national state despite the strong influence of Russian ideology and politics. Some Russian academics, especially those in nationalistic circles (e.g., Valerij Solovej as well as western scholars such as Terry Martin and Geoffrey Hosking stressed that Russians dominated demographically and politically

  7. IEA energy policies review: the European Union

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-09-04

    For the first time, the IEA has reviewed the energy policies of the European Union which shape the energy use of almost 500 million citizens in 27 EU member countries. A unique entity governed under complex and almost constantly evolving structures, the EU constitutes a challenge for energy policy makers. Its energy policy has a global impact, not only because of its 16% share of world energy demand, but also because of the EU leadership in addressing climate change. Strong policy drives are underway in the EU to achieve the completion of the internal energy market, increase renewable energy supply, reduce CO2 emissions and make the EU more energy-efficient. Concerns about security of supply have also led to a greater focus on improved energy relations with supplier countries, and new institutional structures are being put in place. How much progress has been made in the field of security, internal market and external energy policies? And in which of these areas has the EU already implemented a fully integrated policy? This publication addresses these questions and also analyses the impact of the most recent major EU policy measures, in particular the Energy and Climate Package of January 2008 and the 3rd Liberalisation Package of September 2007. This book finds that both of these proposals are highly ambitious. But implementing them and reviewing both volume and allocation of energy R and D will be necessary to achieve a sustainable energy future in a fully competitive integrated EU energy market.

  8. Cogeneration in the former Soviet Union

    International Nuclear Information System (INIS)

    Horak, W.C.

    1997-01-01

    The former Soviet Union made a major commitment to Cogeneration. The scale and nature of this commitment created a system conceptually different from Cogeneration in the west. The differences were both in scale, in political commitment, and in socio economic impact. This paper addresses some of the largest scale Cogeneration programs, the technology, and the residual impact of these programs. The integration of the Cogeneration and nuclear programs is a key focus of the paper. Soviet designed nuclear power plants were designed to produce both electricity and heat for residential and industrial uses. Energy systems used to implement this design approach are discussed. The significant dependence on these units for heat created an urgent need for continued operation during the winter. Electricity and heat are also produced in nuclear weapons production facilities, as well as power plants. The Soviets also had designed, and initiated construction of a number of nuclear power plants open-quotes ATETsclose quotes optimized for production of heat as well as electricity. These were canceled

  9. Management of electricity markets in European Union

    International Nuclear Information System (INIS)

    Zamfir, A.; Florescu, M.S.

    2007-01-01

    The challenges facing energy markets in Europe were discussed with particular reference to the need to integrate and interconnect national energy markets. The Romanian power market evolution since 2000 was also analyzed, taking into account the fact that the strategic objective of the Romanian Government is to assume the role of Regional Exchange in the South-East European region. A common approach to energy is needed to enable the European Union (EU) to compete in global markets, to improve sustainability in the EU and to secure energy supply. An overall framework is needed in order to achieve these objectives. This paper presented the general measures needed to complete the internal gas and electricity markets in Europe. It also proposed measures to ensure that the EU's internal energy market guarantees security of supply and solidarity between Member States. The guiding principles that an approach to information management and market transparency should be based on were described. The authors suggested that an integrated and competitive electricity and gas markets should be established to promote efficient energy services and diversify the energy mix. The measures needed in order to achieve the goal of a genuine single market at EU level were described along with the actions needed to stimulate investments in infrastructure and generation capacity. Measures to prevent or manage energy supply crises were also proposed. 4 refs., 1 tab

  10. Renewable Energy Policy Fact sheet - European Union

    International Nuclear Information System (INIS)

    2017-09-01

    The EurObserv'ER policy profiles give a snapshot of the renewable energy policy in the EU Member States. The European Union aims to achieve a 20% share (with legally binding national targets) of its final energy consumption from RES by 2020, and at least a 27% share (not broken down into nationally binding targets) by 2030. Key instruments at EU level to promote RES include directives, such as the 2009 Renewable Energy Directive. The EU Emission Trading Scheme (ETS) is also intended to support RES. The European Commission has also adopted state aid guidelines to ensure that support schemes to promote RES at national level are compatible with EU competition law and internal market rules. Further instruments are research, development and innovation funding programmes, such as Horizon2020, the Innovation Fund, and the NER300 programme. RES are also supported through regional development funds as well as through grants and loans for RES projects and related infrastructure from the European Investment Bank (EIB) and the European Fund for Strategic Investments (EFSI). A recast directive on the promotion of RES in the period 2020- 2030 is to be adopted along with governance rules to ensure that the EU-wide RES target for 2030 is met

  11. European Union concerns with its energy dependence

    International Nuclear Information System (INIS)

    Commeau, N.

    2001-01-01

    European Union (E.U.) produces only half its needs concerning energy. It is expected that by 2030, the energy balance will be 86% for fossil energies, 8% for renewable energies and 6% for nuclear energy. Different scenario show that the dependence of E.U will worsen and reach 70% unless a common strategy is launched to curb the tendency. E.U is elaborating a common policy concerning energy, this policy rests on 4 axis: 1) monitoring the increase of the energy consumption by promoting energy savings in housing and transport, 2) directing the energy demand towards less polluting energy by using taxes, public funding and European regulations as incentive tools, 3) sustaining a constant dialogues with energy exporting countries in order to get a more stable energy market and have a benefiting influence on prices, and 4) developing new routes of importation of energy by for instance contributing to the construction of new oil or gas pipeline networks. (A.C.)

  12. Câncer de colo uterino: caracterização das mulheres em um município do sul do Brasil Cáncer del cuello uterino: identificación /caracterización de las mujeres en un município del sur de BRAZIL Cervical cancer: characterization of women in a city in the south of BRAZIL

    Directory of Open Access Journals (Sweden)

    Marilu Correa Soares

    2010-03-01

    tienen las prácticas pré-cáncer para la detección precoz y la prevención del cáncer de cuello uterino. El desafio para lograr la integralidad está en la necesidad de repensar el conocimiento y prácticas profesionales en el cuidado a las mulheres, independientemente del motivo que las motivo a buscar el servicio de salud.The aim of this study was to identify and analyze socioeconomic, behavioral and biological characteristics of women with cervical cancer that used public health services in a city in the south of Brazil. This is a qualitative study, realized with twenty women with a diagnosis of cervical cancer. The survey had as theoretical support the integrality of attention to the health. To collect data it was used the information from Information System of Cervical Cancer and a semi-structured interview. Characteristics of age, education, frequency to the medical consultation and the interval of prevent exams were identified. The findings make possible to say that women still have difficulty in considering the importance of pre-cancer in order to precocious detection and prevention of cervical cancer. The challenge to reach integrality is in the necessity of rethinking knowledge and professional practices in the care to women, independent of the reason which led them to the health service.

  13. Il dono del racconto

    DEFF Research Database (Denmark)

    Polito, Paola

    1998-01-01

    L'articolo indaga a vari livelli strutturali del romanzo "Il coraggio del pettirosso" (rete metaforica, dialogismo diegetico, dialogismo come fenomeno di voce, strategie discorsive messe in atto dalla voce narrante, stile colloquiale) la complessa realizzazione testuale del genere narrativo...

  14. Disease burden of chronic lymphocytic leukaemia within the European Union.

    Science.gov (United States)

    Watson, Louise; Wyld, Peter; Catovsky, Daniel

    2008-10-01

    Whilst Chronic lymphocytic leukaemia (CLL) is considered a rare disease, to our knowledge, the current prevalence of CLL within the European Union (EU) member states is not published. Understanding the number of individuals with CLL is vital to assess disease burden within the wider population. Using 2002 data from the International Agency for Research on Cancer, we estimated the number of individuals with CLL (ICD-10 C91.1) from those reported for all leukaemias (C91-95) and extrapolated the figures by the population increase within the EU between 2002 and 2006, the last year with fully updated community population estimates. One- and 5-yr partial prevalence estimates are reported (i.e. the number of individuals still living 1-5 yr post-diagnosis). We then applied proportional estimates from the literature to assess those requiring immediate treatment, those under observation and their likely progression rates. We found that within the 27 EU states plus Iceland, Norway and Lichtenstein, 1- and 5-yr CLL partial prevalence estimates totalled approximately 13,952 and 46,633 individuals respectively in 2006. By applying Binet staging to the 1-yr estimate, 40% of patients will be stage B/C and require immediate treatment. Thus, 5581 individuals may be treated within the first year of diagnosis. Of the 60% (8371) under observation, by 5 yr up to 33% (2763) may have more advanced disease with increased risk of mortality. Whilst CLL is a rare disease, the number of individuals burdened by the disease within the EU is considerable and thousands of patients require treatment and physician care, which has cost implications for member states.

  15. Shop stewards' learning and union strategies

    DEFF Research Database (Denmark)

    Warring, Niels

    2007-01-01

    In Denmark the trade unions have well established educational systems providing the shop stewards with a variety of competencies. Union courses have been analysed focusing on shop stewards' satisfaction with the content and the practical impact of the courses. However, little attention has been...... different theoretical traditions: Shop steward's learning is situational, relational and cross-contextual. Shop stewards' learning is lifelong and life wide. And shop stewards' learning is closely connected to the development of the labour market and not least the unions' priorities, interpretation...

  16. THE NEW ARCHITECTURE OF ECONOMIC GOVERNANCE IN THE EUROPEAN UNION

    Directory of Open Access Journals (Sweden)

    Coroiu Sorina Ioana

    2015-07-01

    Full Text Available The economic crisis that began in 2007-2008 has highlighted the need for a stronger economic coordination at EU level, to ensure financial stability. The new architecture of economic governance in the European Union is based on Fiscal Pact, on Macroeconomic Imbalances Identification Mechanism, on European Stability Mechanism and on Banking Union. Since the banking system is the most significant component of the financial system, we will give more importance to the analysis of Banking Union, which is based on three pillars: The Single Supervisory Mechanism, The Single Resolution Mechanism and The Deposit Guarantee Schemes.

  17. Inmunoterapia del cáncer: Importancia de controlar la inmunosupresión Cancer immunotherapy: Importance of overcoming immune suppression

    Directory of Open Access Journals (Sweden)

    Mariana Malvicini

    2010-12-01

    Full Text Available Es cada vez mayor la evidencia experimental y clínica de que el sistema inmunitario interviene activamente en la patogénesis y el control de la progresión tumoral. Una respuesta antitumoral efectiva depende de la correcta interacción de varios componentes del sistema inmunitario, como las células presentadoras de antígeno y diferentes sub-poblaciones de linfocitos T. Sin embargo, los tumores malignos desarrollan numerosos mecanismos para evadir el reconocimiento y su eliminación por parte del sistema inmunitario. En esta revisión discutiremos algunos de esos mecanismos y posibles estrategias terapéuticas para contrarrestarlos.Increasing evidence indicates that the immune system is involved in the control of tumor progression. Effective antitumor immune response depends on the interaction between several components of the immune system, including antigen-presenting cells and different T cell subsets. However, tumor cells develop a number of mechanisms to escape recognition and elimination by the immune system. In this review we discuss these mechanisms and address possible therapeutic approaches to overcome the immune suppression generated by tumors.

  18. Validación de los códigos diagnósticos de cáncer de colon y recto del Conjunto Mínimo Básico de Datos Validation of colorectal cancer diagnostic codes in a hospital administration data set

    Directory of Open Access Journals (Sweden)

    Mirari Márquez Cid

    2006-08-01

    Full Text Available Objetivo: Validar la capacidad del Conjunto Mínimo Básico de Datos (CMBD para detectar casos incidentes de cáncer de colon y recto utilizando como estándar de referencia el Registro de Cáncer de Murcia (RCM y medir la concordancia entre el CMBD y el registro de cáncer en tumores colorrectales. Material y método: Estudio de validación transversal del CMBD del Hospital Virgen de la Arrixaca de Murcia. La población de estudio son los casos incidentes de colon-recto del año 2000 del RCM y los casos del CMBD en el citado hospital para el mismo año con algún código diagnóstico CIE-9 entre 153.0 y 154.1 eliminando reingresos. Durante el proceso se van a realizar 2 análisis: sólo con el diagnóstico principal y con todos los diagnósticos. Se calcula la sensibilidad, la especificidad, el valor predictivo positivo (VPP y negativo (VPN y la concordancia con sus intervalos de confianza (IC del 95%. Resultados: Con sólo el primer diagnóstico, el CMBD detecta el 80% de los casos incidentes de cáncer colorrectal con un VPP del 75%; considerando todos los diagnósticos, detecta el 85% con un VPP del 64%. La concordancia en la codificación es elevada tanto con 3 dígitos (índice kappa del 88% (IC del 95%, 0,79-0,97 en primer diagnóstico, y del 89% (IC del 95%, 0,80-0,97 en todos los diagnósticos como de 4 dígitos (índice kappa del 77% (IC del 95%, 0,68-0,85 en el primer diagnóstico, y del 78% (IC del 95%, 0,70-0,86 en todos diagnósticos en ambos análisis. Conclusiones: El CMBD es una buena fuente para detectar casos incidentes de cáncer al presentar una elevada sensibilidad. La alta concordancia encontrada en las localizaciones tumorales de colon-recto contribuye a consolidar el CMBD como fuente de datos para los registros de cáncer.Objectives: To validate the ability of a hospital administration data set (minimum data set [MDS] to detect incident cases of colorectal cancer using the Murcia Cancer Registry (MCR as the gold standard

  19. Calidad del Programa de Detección Oportuna de Cáncer Cervicouterino en el estado de Nuevo León Quality of the Early Cervical Cancer Detection Program in the state of Nuevo León

    Directory of Open Access Journals (Sweden)

    ANA MARÍA SALINAS-MARTÍNEZ

    1997-05-01

    Full Text Available Objetivo. Determinar la calidad del Programa de Detección Oportuna de Cáncer Cervicouterino en Nuevo León. Material y métodos. Se analizaron 4 791 informes citológicos emitidos por los módulos de detección oportuna de la Secretaría de Salud Estatal, el Hospital Universitario y el Instituto Mexicano del Seguro Social, seleccionados al azar. Se excluyeron aquellos que pertenecían a mujeres con histerectomía, embarazo actual, menopausia o resultado citológico positivo. La calidad se midió con apego a estándares. El análisis incluyó, además de la estadística descriptiva, pruebas para diferencias de proporciones y de medias. Resultados. La calidad del Programa fue moderadamente satisfactoria en el ámbito estatal. La calidad de la toma de la muestra fue poco satisfactoria; 39.9% presentó células endocervicales. La calidad en términos de la cobertura fue poco satisfactoria; 15.6% correspondió a mujeres de 25 y más años atendidas por primera vez. La calidad en términos de la oportunidad fue muy satisfactoria; 8.5 ± .7 días hábiles entre las fechas de toma e interpretación. Conclusiones. Se requiere de estrategias para incrementar el impacto del Programa en el estado, tales como el mejoramiento en la calidad de la toma de la muestra y de la cobertura.Objective. To determine the quality of the Early Cervical Cancer Detection Program in the state of Nuevo León. Material and methods. A random selection of 4 791 cytologic reports were analyzed, emitted by the State Ministry of Health, the University Hospital and the Mexican Institute for Social Security early cervical cancer detection modules. Pap tests of women with hysterectomy, current pregnancy, menopause or positive result were excluded. Quality was measured with previously defined standards. Analysis included, besides univariate statistics, tests of significance for proportions and means. Results. The quality of the program was fairly satisfactory at the level of the State

  20. UNIONES EN HENDIDURA Y SU PAPEL FUNCIONAL EN EL TRACTO REPRODUCTOR FEMENINO

    OpenAIRE

    Brañes O,María C.; Sáez R,Alejandra; Villalón B,Manuel J; Sáez C,Juan C

    2004-01-01

    En el aparato reproductor femenino se expresan diferentes conexinas (Cxs), proteínas que forman canales de uniones en hendidura (CUH) entre células en contacto, permitiendo la coordinación de respuestas metabólicas y/o eléctricas de grupos celulares. Los CUH jugarían un papel relevante en el desarrollo de las células de la granulosa, ya que permiten la comunicación heteróloga entre el ovocito y las células del cúmulo manteniendo la detención meiótica. En la trompa de Falopio, los CUH coordina...