WorldWideScience

Sample records for cancer research meeting

  1. Cancer research meets evolutionary biology.

    Science.gov (United States)

    Pepper, John W; Scott Findlay, C; Kassen, Rees; Spencer, Sabrina L; Maley, Carlo C

    2009-02-01

    There is increasing evidence that Darwin's theory of evolution by natural selection provides insights into the etiology and treatment of cancer. On a microscopic scale, neoplastic cells meet the conditions for evolution by Darwinian selection: cell reproduction with heritable variability that affects cell survival and replication. This suggests that, like other areas of biological and biomedical research, Darwinian theory can provide a general framework for understanding many aspects of cancer, including problems of great clinical importance. With the availability of raw molecular data increasing rapidly, this theory may provide guidance in translating data into understanding and progress. Several conceptual and analytical tools from evolutionary biology can be applied to cancer biology. Two clinical problems may benefit most from the application of Darwinian theory: neoplastic progression and acquired therapeutic resistance. The Darwinian theory of cancer has especially profound implications for drug development, both in terms of explaining past difficulties, and pointing the way toward new approaches. Because cancer involves complex evolutionary processes, research should incorporate both tractable (simplified) experimental systems, and also longitudinal observational studies of the evolutionary dynamics of cancer in laboratory animals and in human patients. Cancer biology will require new tools to control the evolution of neoplastic cells.

  2. Towards meeting the research needs of Australian cancer consumers

    Directory of Open Access Journals (Sweden)

    Saunders Carla

    2012-12-01

    Full Text Available Abstract Background There is a growing amount of literature to support the view that active involvement in research by consumers, especially informed and networked consumers, benefits the quality and direction of research itself, the research process and, most importantly, people affected by cancer. Our exploratory project focuses on identifying their priorities and developing a process to assess the research needs of Australian cancer consumers which may be useful beyond the cancer scenario. Methods This project was consumer initiated, developed and implemented, with the assistance of a leading Australian cancer consumer advocacy group, Cancer Voices NSW (CVN. Such direct involvement is unusual and ensures that the priorities identified, and the process itself, are not influenced by other interests, regardless how well-intentioned they may be. The processes established, and data collection via a workshop, followed by a questionnaire to confirm and prioritise findings, and comparison with a similar UK exercise, are detailed in this paper. Results Needs across five topic areas reflecting cancer control domains (prevention and risk; screening and diagnosis; treatment; survivorship; and end of life were identified. Cancer consumers high priority research needs were found to be: earlier diagnosis of metastatic cancers; the extent of use of best practice palliative care guidelines; identifying barriers to cancer risk behaviour change; and environmental, nutrition and lifestyle risk factors for people with cancer. A process for identifying consumers’ research priorities was developed and applied; this may be useful for further investigation in this under-studied area. Conclusion The findings provide a model for developing a consumer derived research agenda in Australia which can be used to inform the strategic direction of cancer research. Consumers have been seeking a workable method to achieve this and have worked in collaboration with a major

  3. Cancer Research

    Science.gov (United States)

    NCI is the nation's leader in cancer research. Learn more about NCI's cancer research areas, key initiatives, progress made in cancer research, and resources for researchers like research tools, specimens and data.

  4. 78 FR 27408 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-10

    ... Methods for the Detection of Cancer Recurrence in Post-Therapy Breast Cancer Patients. Date: June 4, 2013... Prevention Research; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings...

  5. 75 FR 14172 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-03-24

    ... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings... Emphasis Panel, Nucleic Acid Analysis for the Molecular Characterization of Cancer. Date: April 6, 2010... Biology Research; 93.397, Cancer Centers Support; 93.398, Cancer Research Manpower; 93.399, Cancer Control...

  6. 75 FR 79010 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-12-17

    ... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings... Cancer Institute Special Emphasis Panel. Development of Devices for Point of Care Analysis of Circulating... Biology Research; 93.397, Cancer Centers Support; 93.398, Cancer Research Manpower; 93.399, Cancer Control...

  7. 75 FR 21002 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-04-22

    ... Panel, SPORE in Lymphoma and Breast Cancer. Date: June 15-16, 2010. Time: 5 p.m. to 5 p.m. Agenda: To...; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings...

  8. 75 FR 3239 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-20

    ... Special Emphasis Panel, Basal-like Breast Cancer Assay. Date: March 10, 2010. Time: 8 a.m. to 7 p.m..., Cancer Cause and Prevention Research; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings...

  9. 76 FR 16431 - National Cancer Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-03-23

    ... Committee: National Cancer Institute Special Emphasis Panel; SPORE in Lymphoma, Breast, Ovarian... and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meeting...

  10. 76 FR 17930 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-03-31

    ... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings... Special Emphasis Panel; Innovative Emerging Molecular Analysis Technologies. Date: June 2-3, 2011. Time: 8..., Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology...

  11. 77 FR 24969 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-04-26

    ... . Name of Committee: National Cancer Institute Special Emphasis Panel; SPORE in Breast, Prostate and... Construction; 93.393, Cancer Cause and Prevention Research; 93.394, Cancer Detection and Diagnosis Research; 93... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings...

  12. Workshop on Cancer Research

    International Nuclear Information System (INIS)

    Vermorken, A.; Durieux, L.

    1991-01-01

    On April, 22-24 April 1991, the Hungarian National Institute of Oncology and the Commission of the European Communities have organized a workshop on Cancer Research. The aim of the meeting was to provide the participants information on the ongoing research in Hungary and in Member States. The topic is of importance for Hungary and it was also considered that the meeting could contribute to identify subjects of possible collaboration between Hungarian and Member State laboratories in the case financial support would become available. Three papers about new therapies under development were presented proton therapy and Boron neutron capture therapy

  13. Types of Cancer Research

    Science.gov (United States)

    An infographic from the National Cancer Institute (NCI) describing the four broad categories of cancer research: basic research, clinical research, population-based research, and translational research.

  14. Fossil energy research meeting

    Energy Technology Data Exchange (ETDEWEB)

    Kropschot, R. H.; Phillips, G. C.

    1977-12-01

    U.S. ERDA's research programs in fossil energy are reviewed with brief descriptions, budgets, etc. Of general interest are discussions related to the capabilities for such research of national laboratories, universities, energy centers, etc. Of necessity many items are treated briefly, but a general overview of the whole program is provided. (LTN)

  15. 78 FR 55750 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-11

    ... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings... Innovative Molecular Analysis Technology Development for Cancer Research (R21). Date: October 24, 2013. Time...: National Cancer Institute Special Emphasis Panel; Integrative Cancer Biology. Date: October 29, 2013. Time...

  16. 7th Young Researcher Meeting

    International Nuclear Information System (INIS)

    2017-01-01

    Young Researcher Meeting, Torino 2016 F Agostini, C Antolini, A Avella, G Cattani, R Cuccaro, A Cultrera, M Di Stefano, G Fragione, L Lolli, M Migliaccio, L Pagnanini, E Pessana, F Piacentini, D Pietrobon, E Pusceddu, R Romeo, M Serra, E Simonetto, F Stellato Preface The Young Researcher Meeting (www.yrmr.it) has been established as a forum for students, postdoctoral fellows and young researchers determined to play a proactive role in the scientific progress. Since 2009 we run itinerant yearly meetings to discuss the most recent developments and achievements in Physics, as we are firmly convinced that sharing expertise and experience is the foundation of the research activity. One of the main purposes of the conference is actually to create an international network of young researchers, both experimentalists and theoreticians, and fruitful collaborations across the different branches of Physics. The format we chose is an informal meeting primarily aimed at students and researchers at the beginning of their scientific career, who are encouraged to present their work in brief presentations able to provide genuine engagement of the audience and cross-pollination of ideas. The 7 th edition of the Young Researcher Meeting was held at the Istituto Nazionale di Ricerca Metrologica (INRiM) in Turin, the Italian National Metrology Institute responsible for the national standards of the International System of Units. The conference took place from Monday 24 th to Wednesday 26 th October 2016. This edition gathered 120 participants belonging to universities and research centres from all over the world. The plenary talk sessions covered several areas of pure and applied Physics, and they were complemented by an extremely rich and interactive poster session, which was also extended to the coffee breaks. The programme included a “poster and wine” session on the first evening, a guided tour at the Turin Astrophysical Observatory and a very enjoyable and friendly conference

  17. Reports from the 2010 Clinical and Translational Cancer Research Think Tank meeting: design strategies for personalized therapy trials.

    Science.gov (United States)

    Berry, Donald A; Herbst, Roy S; Rubin, Eric H

    2012-02-01

    It has long been evident that cancer is a heterogeneous disease, but only relatively recently have we come to realize the extent of this heterogeneity. No single therapy is effective for every patient with tumors having the same histology. A clinical strategy based on a single-therapy approach results in overtreatment for the majority of patients. Biomarkers can be considered as knives that dissect the disease ever more finely. The future of clinical research will be based on learning whether certain therapies are more appropriate than others for biomarker-defined subsets of patients. Therapies will eventually be tailored to narrow biomarker subsets. The ability to determine which therapies are appropriate for which patients requires information from biological science as well as empirical evidence from clinical trials. Neither is easy to achieve. Here we describe some nascent approaches for designing clinical trials that are biomarker-based and adaptive. Our focus is on adaptive trials that address many questions at once. In a way, these clinical experiments are themselves part of a much larger experiment: learning how (or whether it is possible) to design experiments that match patients in small subsets of disease with therapies that are especially effective and possibly even curative for them.

  18. Nebraska Prostate Cancer Research Program

    Science.gov (United States)

    2015-10-01

    Khan then phoned Dr. Lin regarding the conclusion of meeting with students’ evaluation and expressed students’ positive attitude toward research...nitrocellulose membrane, membranes were blocked with 5% non-fat milk Novel Imidazopyridines in Castration-Resistant Prostate Cancer PLOS ONE | DOI

  19. 2013 Building America Research Planning Meeting Summary

    Energy Technology Data Exchange (ETDEWEB)

    Metzger, C. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hunt, S. [Confluence Communications, Missoula, MT (united States)

    2014-02-01

    The Building America Research Planning Meeting was held October 28-30, 2013, in Washington, DC. This meeting provides one opportunity each year for the research teams, national laboratories and Department of Energy (DOE) managers to meet in person to share the most pertinent information and collaboration updates. This report documents the presentations, highlights key program updates, and outlines next steps for the program.

  20. Peralta Cancer Research Institute

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    The investigators in the cell biology program at PCRI have pioneered in the development of techniques for culturing human epithelial cells. The cancer diagnosis program has been concerned with researching new techniques for early diagnosis of breast cancer in women. The cancer treatment program has been concerned with applying cell biology and biochemistry advances to improve cancer management

  1. Cancer research and radiotherapy

    International Nuclear Information System (INIS)

    Matsuzawa, Taiju

    1978-01-01

    An actual condition of cancer, and the basis and a future view of radiotherapy were described by adding generally established biological and biochemical knowledge to the author's research. It was described that the relapse of cancer after irradiation was induced from outside of cancerous mass, and the nature of relapsed cancerous cells group was also stated. The histological structure of cancer from a view of cell movement and radioresistant cancerous cells group were described. The differentiation of cancerous cells were described, and a study of inhibition of cancer by redifferentiation was considered. It is important to grasp characteristics and a limit of radiotherapy for cancer, to systematize and materialize reasonable therapy which uses drug and immunotherapy together with surgery, and to use radiotherapy reasonably together with redifferentiation therapy of cancerous cells by extracting characteristics and a limit of radiationtherapy from an actual condition of cancer. (Serizawa, K.)

  2. Summary of fuel safety research meeting 2004

    International Nuclear Information System (INIS)

    Fuketa, Toyoshi; Hidaka, Akihide; Nakamura, Jinichi; Suzuki, Motoe; Nagase, Fumihisa; Sasajima, Hideo; Fujita, Misao; Otomo, Takashi; Kudo, Tamotsu; Amaya, Masaki; Sugiyama, Tomoyuki; Ikehata, Hisashi; Iwasaki, Ryo; Ozawa, Masaaki; Kida, Mitsuko

    2004-10-01

    Fuel Safety Research Meeting 2004, which was organized by the Japan Atomic Energy Research Institute, was held on March 1-2, 2004 at Toranomon Pastoral, Tokyo. The purposes of the meeting are to present and discuss the results of experiments and analyses on reactor fuel safety and to exchange views and experiences among the participants. The technical topics of the meeting covered the status of fuel safety research activities, fuel behavior under RIA and LOCA conditions, high burnup fuel behavior, and radionuclides release under severe accident conditions. This summary contains all the abstracts and OHP sheets presented in the meeting. (author)

  3. 2013 Building America Research Planning Meeting Summary

    Energy Technology Data Exchange (ETDEWEB)

    Metzger, Cheryn E. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hunt, Stacy [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2014-02-01

    The Building America (BA) Research Planning Meeting was held October 28-30, 2013, in Washington, DC. This meeting provides one opportunity each year for the research teams, national laboratories and Department of Energy (DOE) managers to meet in person to share the most pertinent information and collaboration updates. This report documents the presentations, highlights key program updates, and outlines next steps for the program.

  4. Proceedings of fuel safety research specialists' meeting

    International Nuclear Information System (INIS)

    Suzuki, Motoe

    2002-08-01

    Fuel Safety Research Specialists' Meeting, which was organized by Japan Atomic Energy Research Institute, was held on March 4-5, 2002 at JAERI in Tokai Establishment. Purposes of the Meeting are to exchange information and views on LWR fuel safety topics among the specialist participants from domestic and foreign organizations, and to discuss the recent and future fuel research activities in JAERI. In the Meeting, presentations were given and discussions were made on general report of fuel safety research activities, fuel behaviors in normal operation and accident conditions, FP release behaviors in severe accident conditions, and JAERI's ''Advanced LWR Fuel Performance and Safety Research Program''. A poster exhibition was also carried out. The Meeting significantly contributed to planning future program and cooperation in fuel research. This proceeding integrates all the pictures and papers presented in the Meeting. The 10 of the presented papers are indexed individually. (J.P.N.)

  5. Meet-U: Educating through research immersion.

    Science.gov (United States)

    Abdollahi, Nika; Albani, Alexandre; Anthony, Eric; Baud, Agnes; Cardon, Mélissa; Clerc, Robert; Czernecki, Dariusz; Conte, Romain; David, Laurent; Delaune, Agathe; Djerroud, Samia; Fourgoux, Pauline; Guiglielmoni, Nadège; Laurentie, Jeanne; Lehmann, Nathalie; Lochard, Camille; Montagne, Rémi; Myrodia, Vasiliki; Opuu, Vaitea; Parey, Elise; Polit, Lélia; Privé, Sylvain; Quignot, Chloé; Ruiz-Cuevas, Maria; Sissoko, Mariam; Sompairac, Nicolas; Vallerix, Audrey; Verrecchia, Violaine; Delarue, Marc; Guérois, Raphael; Ponty, Yann; Sacquin-Mora, Sophie; Carbone, Alessandra; Froidevaux, Christine; Le Crom, Stéphane; Lespinet, Olivier; Weigt, Martin; Abboud, Samer; Bernardes, Juliana; Bouvier, Guillaume; Dequeker, Chloé; Ferré, Arnaud; Fuchs, Patrick; Lelandais, Gaëlle; Poulain, Pierre; Richard, Hugues; Schweke, Hugo; Laine, Elodie; Lopes, Anne

    2018-03-01

    We present a new educational initiative called Meet-U that aims to train students for collaborative work in computational biology and to bridge the gap between education and research. Meet-U mimics the setup of collaborative research projects and takes advantage of the most popular tools for collaborative work and of cloud computing. Students are grouped in teams of 4-5 people and have to realize a project from A to Z that answers a challenging question in biology. Meet-U promotes "coopetition," as the students collaborate within and across the teams and are also in competition with each other to develop the best final product. Meet-U fosters interactions between different actors of education and research through the organization of a meeting day, open to everyone, where the students present their work to a jury of researchers and jury members give research seminars. This very unique combination of education and research is strongly motivating for the students and provides a formidable opportunity for a scientific community to unite and increase its visibility. We report on our experience with Meet-U in two French universities with master's students in bioinformatics and modeling, with protein-protein docking as the subject of the course. Meet-U is easy to implement and can be straightforwardly transferred to other fields and/or universities. All the information and data are available at www.meet-u.org.

  6. The 10. Danish marine research meeting

    International Nuclear Information System (INIS)

    1998-01-01

    The publication comprises the programme for the 10th Danish meeting for marine researchers held in Hirtshals (Denmark) on January 21 - 27, 1998, and the abstracts of the papers that were presented at that meeting. Subjects covered are marine biology, sediments and sedimentation, fish, fishing and fishing regulations, marine processes and the monitoring of Danish straits. (EG)

  7. 8. Danish meeting for marine researchers

    International Nuclear Information System (INIS)

    1994-01-01

    The publication comprises the programme for the 8th Danish meeting for marine researchers held in Odense (Denmark) on January 25th - 27th, 1994, and the abstracts of the papers that were presented at that meeting. Subjects covered are marine biology, sediments and sedimentation, fish, fishing and fishing regulation, marine processes and the monitoring of Danish straits. (AB)

  8. Translational research in pancreatic cancer. Highlights from the "44th ASCO Annual Meeting". Chicago, IL, USA. May 30 - June 3, 2008.

    Science.gov (United States)

    Saif, Muhammad Wasif

    2008-07-10

    Pancreatic cancer is an international problem because of its increasing incidence worldwide. The incidence and age-adjusted mortality rates are almost equal, underscoring the aggressive nature of the disease. Although efforts are being made to unveil the principles governing the initiation and progression of this cancer, and to identify the factors that confer its particular aggressiveness, the exact succession of molecular events underlying the development of this devastating malignancy has remained unsolved. The management of pancreatic cancer is, therefore, an ongoing challenge. Many translational studies were presented at the annual meeting of the American Society of Clinical Oncology (ASCO) this year. The author summarizes few of them including: polymorphisms of genes involved in gemcitabine metabolism correlate with prognosis in patients receiving neoadjuvant therapy for pancreatic cancer, diagnostic performance of MUC1 for pancreatic ductal adenocarcinoma, and use of whole genome expression analysis of pancreatic adenocarcinoma to predict prognosis after surgery. Pancreatic cancer remains a dismal disease and early diagnostic markers and therapeutic targets are urgently needed.

  9. Nanotechnology in Cancer Research

    Science.gov (United States)

    The NCI Office of Cancer Nanotechnology Research has had a major impact on bringing novel nano-enabled solutions through the pre-clinical space. The strategic framework of this effort is presented here.

  10. CCR Interns | Center for Cancer Research

    Science.gov (United States)

    The Cancer Research Interns (CRI) Summer Program was inaugurated in 2004 to increase the diversity of trainee applicants to the Center for Cancer Research (CCR). We have placed 339 students from 2004 to 2017, in labs and branches across the CCR. The Division provides the training dollars, some Service & Supply funds, and travel support for those students who meet the financial eligibility criteria (View and/or print the 2018 flier).

  11. Summary of fuel safety research meeting 2005

    International Nuclear Information System (INIS)

    Fuketa, Toyoshi; Nakamura, Takehiko; Nagase, Fumihisa; Nakamura, Jinichi; Suzuki, Motoe; Sasajima, Hideo; Sugiyama, Tomoyuki; Amaya, Masaki; Kudo, Tamotsu; Chuto, Toshinori; Tomiyasu, Kunihiko; Udagawa, Yutaka; Ikehata, Hisashi; Kida, Mitsuko; Ikatsu, Nobuhiko; Hosoyamada, Ryuji; Hamanishi, Eizou; Iwasaki, Ryo; Ozawa, Masaaki

    2006-03-01

    Fuel Safety Research Meeting 2005, which was organized by the Japan Atomic Energy Agency (Establishment of the new organization in Oct. 1, 2005 integrated of JAERI and JNC) was held on March 2-3, 2005 at Toshi Center Hotel, Tokyo. The purposes of the meeting are to present and discuss the results of experiments and analyses on reactor fuel safety and to exchange views and experiences among the participants. The technical topics of the meting covered the status of fuel safety research activities, fuel behavior under Reactivity Initiated Accident (RIA) and Loss of coolant accident (LOCA) conditions, high fuel behavior, and radionuclide release under severe accident conditions. This summary contains all the abstracts and sheets of viewgraph presented in the meeting. (author)

  12. Cancer Research UK | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cancer Research UK. Cancer Research UK. https://www.cancerresearchuk.org/. The Economics of Tobacco Control Research Initiative. The Economics of Tobacco Control Research Initiative funds innovative fiscal policy research supporting tobacco control in low and middle-income countries. View more. The Economics ...

  13. 75 FR 42449 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2010-07-21

    ... Research Programs and Updates of the Implementation of the Clinical Trials and Translational Research....395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers Support; 93...

  14. CCR Interns | Center for Cancer Research

    Science.gov (United States)

    The Cancer Research Interns (CRI) Summer Program was inaugurated in 2004 to provide an open door for students looking for an initial training opportunity. The goal is to enhance diversity within the CCR (Center for Cancer Research) training program and we have placed 338 students from 2004 to 2017, in labs and branches across the division.  The CCR and the Center for Cancer Training’s Office of Training and Education provide stipend support, some Service & Supply funds, and travel support for those students who meet the financial eligibility criteria (

  15. University Research Consortium annual review meeting program

    International Nuclear Information System (INIS)

    1996-07-01

    This brochure presents the program for the first annual review meeting of the University Research Consortium (URC) of the Idaho National Engineering Laboratory (INEL). INEL is a multiprogram laboratory with a distinctive role in applied engineering. It also conducts basic science research and development, and complex facility operations. The URC program consists of a portfolio of research projects funded by INEL and conducted at universities in the United States. In this program, summaries and participant lists for each project are presented as received from the principal investigators

  16. University Research Consortium annual review meeting program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    This brochure presents the program for the first annual review meeting of the University Research Consortium (URC) of the Idaho National Engineering Laboratory (INEL). INEL is a multiprogram laboratory with a distinctive role in applied engineering. It also conducts basic science research and development, and complex facility operations. The URC program consists of a portfolio of research projects funded by INEL and conducted at universities in the United States. In this program, summaries and participant lists for each project are presented as received from the principal investigators.

  17. Training the Cancer Research Workforce

    Science.gov (United States)

    The National Cancer Institute (NCI) builds up the nation's cancer research workforce through training and career development grants, as well as intramural research experiences at the NIH Clinical Center and NCI offices and laboratories in Maryland.

  18. Integrated Cancer Repository for Cancer Research

    Science.gov (United States)

    2017-05-05

    Pancreatic Cancer; Thyroid Cancer; Lung Cancer; Esophageal Cancer; Thymus Cancer; Colon Cancer; Rectal Cancer; GIST; Anal Cancer; Bile Duct Cancer; Duodenal Cancer; Gallbladder Cancer; Gastric Cancer; Liver Cancer; Small Intestine Cancer; Peritoneal Surface Malignancies; Familial Adenomatous Polyposis; Lynch Syndrome; Bladder Cancer; Kidney Cancer; Penile Cancer; Prostate Cancer; Testicular Cancer; Ureter Cancer; Urethral Cancer; Hypopharyngeal Cancer; Laryngeal Cancer; Lip Cancer; Oral Cavity Cancer; Nasopharyngeal Cancer; Oropharyngeal Cancer; Paranasal Sinus Cancer; Nasal Cavity Cancer; Salivary Gland Cancer; Skin Cancer; CNS Tumor; CNS Cancer; Mesothelioma; Breastcancer; Leukemia; Melanoma; Sarcoma; Unknown Primary Tumor; Multiple Myeloma; Ovarian Cancer; Endometrial Cancer; Vaginal Cancer

  19. PREFACE: Young Researcher Meeting, Trieste 2013

    Science.gov (United States)

    Agostini, F.; Antolini, C.; Aversa, R.; Cattani, G.; Martinelli, M.; Mazzaferro, L.; Migliaccio, M.; Paci, F.; Pietrobon, D.; Ricci Pacifici, D.; Stellato, F.; Veneziani, M.

    2013-12-01

    YRM logo The Young Researcher Meeting (www.yrmr.it) has been a rapidly growing event for the last few years. Together with other initiatives which have emerged in several research areas, the young researcher meeting marks the awareness and the desire of PhD students, postdoctoral fellows and young researchers to play a major role in scientific progress. Devoted to the discussion and the interchange of new developments and ideas in physics, the meeting is primarily aimed at graduate students and postdoctoral researchers, who are encouraged to present their work in an informal atmosphere. One of the main purposes of the conference is to create an international network of young researchers, both experimentalists and theorists, and fruitful collaborations across the different branches of physics. Born in Rome in 2009, after three editions that strengthened it, the Young Researcher Meeting 2013 was held in Trieste. Propelled by the past success, the fourth meeting was a two-day conference on 3-4June. It was sponsored by the International School for Advanced Studies - SISSA - and the University of Padova, thus acquiring an even further international drive. In this volume, we collect some of the contributions that were presented at the conference. They cover topics in astrophysics and cosmology, particle and theoretical physics, soft and condensed matter, biophysics and medical physics. YRM Organising and Editorial Committee Fabio Agostini (fabio.agostini@roma2.infn.it) Dipartimento di Fisica, Università di Roma 'Tor Vergata' Via della Ricerca Scientifica 1, 00133 Roma, Italy Claudia Antolini (claudia.antolini@sissa.it) SISSA - Scuola Internazionale Superiore di Studi Avanzati Via Bonomea 265, 34136 Trieste, Italy Rossella Aversa (raversa@sissa.it) SISSA - Scuola Internazionale Superiore di Studi Avanzati Via Bonomea 265, 34136 Trieste, Italy Giordano Cattani (giordano.cattani@gmail.com) Matteo Martinelli (mmartin@sissa.it) SISSA - Scuola Internazionale Superiore di

  20. Cancer Prevention Research in China.

    Science.gov (United States)

    Yu, Siwang; Yang, Chung S; Li, Junyao; You, Weicheng; Chen, Jianguo; Cao, Ya; Dong, Zigang; Qiao, Youlin

    2015-08-01

    Although cancer incidence and mortality rates in the United States and some European countries have started to decrease, those in developing countries are increasing. China, the most populous developing country, is facing a serious challenge from cancer. Cancer incidence has been increasing for decades, and cancer is the leading cause of death in China. In 2012, the cancer incidence was 174.0 per 100,000, and the cancer mortality was 122.2 per 100,000 in China. In addition to the still-prevalent traditional Chinese cancers of the stomach, liver, esophagus, cervix, and nasopharynx, the incidence of "Western" cancers such those of the lung, breast, and colorectum has increased alarmingly in recent years. These increases are likely due to the lifestyle and environmental changes associated with rapid economic development and population aging. More importantly, a large portion of these cancers are preventable. Researchers in China have made important contributions to cancer prevention research, especially in the traditional Chinese cancers. More cancer prevention research and measures, especially on the major emerging cancers, are urgently needed. This review article highlights some of the past achievements and present needs in cancer prevention research in China and suggests important areas for future studies. ©2015 American Association for Cancer Research.

  1. Expert Meeting Report. Foundations Research Results

    Energy Technology Data Exchange (ETDEWEB)

    Ojczyk, C. [Univ. of Minnesota, St. Paul, MN (United States); Huelman, P. [Univ. of Minnesota, St. Paul, MN (United States); Carmody, J. [Univ. of Minnesota, St. Paul, MN (United States)

    2013-05-01

    The NorthernSTAR Building America Partnership held an expert meeting on Foundations–Research Results on November 15, 2011, in Minneapolis, MN. Audience participation was actively encouraged during each presentation to uncover needs and promote dialog among researchers and industry professionals. Key results were: greater understanding of the role of moisture transport through foundation and insulation materials and its potential impact on building durability; greater understanding of the role of foundation type in the process of selecting an insulation system for energy performance and building durability; need for research to quantify the risks associated with insulation processes to better enable users to weigh costs and benefits against the existing conditions of a home; need for improved performance modeling capabilities that address variations in foundation types and soil conditions.

  2. Cancer Research in the Media

    Science.gov (United States)

    Cancer Research in the Media (CRiM) is a two-day seminar designed for international journalists to increase their understanding of complex scientific findings, improving their ability to communicate accurate cancer-related information to the public.

  3. Why I Do Cancer Research

    Science.gov (United States)

    World Cancer Research Day is recognized on September 24, 2017. This day presents an opportunity for all of us to remind the world of the critically important roles research and cancer researchers play in reducing the global burden of cancer. Together with ten other global partners, NCI participated in the planning and launch of this initiative, highlighting the amplified impact of international cooperation in the clinical research arena.

  4. 78 FR 52997 - Connected Vehicle Research Program Public Meeting; Notice of Public Meeting

    Science.gov (United States)

    2013-08-27

    ... DEPARTMENT OF TRANSPORTATION Connected Vehicle Research Program Public Meeting; Notice of Public... overview of the ITS JPO Connected Vehicle research program. The meeting will take place September 24 to 26... . The public meeting is the best opportunity to learn details about the Connected Vehicle research...

  5. PREFACE: Young Researcher Meeting, Trieste 2014

    Science.gov (United States)

    Agostini, F.; Antolini, C.; Aversa, R.; Cattani, G.; Di Stefano, M.; Longobardi, M.; Martinelli, M.; Miceli, A.; Migliaccio, M.; Paci, F.; Pietrobon, D.; Pusceddu, E.; Stellato, F.

    2014-12-01

    YRM_LOGO The Young Researcher Meeting (www.yrmr.it) has confirmed once again this year the enthusiasm and determination of Ph.D. students, postdoctoral fellows and young researchers to play a major role in the scientific progress. Since 2009, we regularly gather together to discuss the most recent developments and achievements in Physics, firmly convinced that sharing our expertise and experience is the foundation of research activity. The format we chose is an informal meeting primarily aimed at graduate students and postdoctoral researchers, who are encouraged to present their work in brief presentations that provide genuine engagement of the audience and cross-pollination of ideas. One of the main purposes of the conference is to create an international network of young researchers, both experimentalists and theorists, and fruitful collaborations across the different branches of Physics. After four editions that strengthened it, the Young Researcher Meeting 2014 was held at the International School for Advanced Studies - SISSA, Trieste, for the second time. The fifth appointment was a two-day conference on July 14th-15th 2014. It has been sponsored by a number of research groups of SISSA, the University of Udine and the Solar Physics group of the University of Rome "Tor Vergata", thus gathering even broader support than previous editions. The success of this year event is testified by an increased number of participants and institutions all around Europe. This resulted in an extremely rich and interactive poster session that covered several areas of pure and applied Physics. With the intent of broadening the contents and stimuli adopting multidisciplinary tools, the YRM 2014 hosted the workshop "Communicating Science" held in collaboration with SISSA Medialab. This choice reflects the growing importance of the outreach activity performed by scientists, especially at the earliest stages of their career, as a way of increasing their expertise and developing soft

  6. 78 FR 44577 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2013-07-24

    ... and AIDS Malignancy priorities. Place: National Cancer Institute, NIH, Building 10, Room 10S255, 10... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute.... App.), notice is hereby given of a meeting of the National Cancer Institute Board of Scientific...

  7. 75 FR 5092 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-02-01

    ... . Name of Committee: National Cancer Institute Special Emphasis Panel, Quantitative Cell-Based Imaging....396, Cancer Biology Research; 93.397, Cancer Centers Support; 93.398, Cancer Research Manpower; 93.399... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute...

  8. 76 FR 52960 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-24

    ... Emphasis Panel, Mechanisms of Cell Signaling in Cancer. Date: October 13-14, 2011. Time: 3 to 5 p.m. Agenda..., Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers Support; 93.398... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute...

  9. US-LA CRN Clinical Cancer Research in Latin America

    Science.gov (United States)

    The United States – Latin America Cancer Research Network (US-LA CRN) convened its Annual Meeting, in coordination with the Ministry of Health of Chile to discuss the Network’s first multilateral clinical research study: Molecular Profiling of Breast Cancer (MPBC).

  10. Expert Meeting Report: Foundations Research Results

    Energy Technology Data Exchange (ETDEWEB)

    Ojczyk, C.; Huelman, P.; Carmody, J.

    2013-05-01

    In the Expert Meeting Plan, the NorthernSTAR Team proposed to host two Expert Meetings in calendar year 2011. Invitees to the meetings would include experts in the current field of study, other BA team members, and representatives from DOE and NREL. They will invite leading industry experts to present at these meetings. The Expert Meetings will focus on key systems areas that will be required to meet the Building America performance goals and shall be sufficiently narrow in scope that specific conclusions, action items, and delegation of future tasks can be identified and completed. The two expert meeting topics are 'Foundations' and 'Window Retrofit.' The first session is designed as a webinar only and the second will be a live meeting.

  11. Research Associate | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives.  The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI’s intramural Center for Cancer Research (CCR).  The dedicated units provide electron microscopy, protein characterization, protein expression, optical microscopy and nextGen sequencing. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research.  CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise. KEY ROLES/RESPONSIBILITIES We are seeking a highly motivated Research Associate II to join the newly established Single Cell Analysis Facility (SCAF) of the CCR at NCI.  The SCAF will house state of the art single cell sequencing technologies including 10xGenomics Chromium, BD Genomics Rhapsody, DEPPArray, and other emerging single cell technologies. This person will work under the guidance of SCAF senior staff to carry out single cell sequencing experiments.

  12. PREFACE: Young Researcher Meeting in Rome 2012

    Science.gov (United States)

    Agostini, Fabio; Cattani, Giordano; Mazzaferro, Luca; Migliaccio, Marina; Pietrobon, Davide; Ricci Pacifici, Daniel; Stellato, Francesco; Veneziani, Marcella

    2012-10-01

    Conference logo At its third edition, the Young Researcher Meeting in Rome (YRMR) proves to be a growing event in the Italian scientific panorama. The high-quality content of the abstracts submitted to the scientific committee resulted in an exciting conference, held, for the second time, at the University of Rome 'Tor Vergata' on 20 January 2012. A busy schedule covered a large variety of cutting-edge science topics: fundamental interactions, particle physics, cosmology, astrophysics, condensed matter and biomedical physics. The broad range of the subjects discussed is the distinctive feature of the YRMR, a meeting aimed at enhancing the synergy among complementary branches of science by stimulating a fruitful exchange between theoretical, experimental and computational physics. Promoting collaborations between PhD students, postdoctoral fellows and young researchers creates a solid scientific network with an open-minded approach to discovery. In this volume, we collect the contributions that have been presented both in the form of talks and of posters. YRMR Organising and Editorial Committee Fabio Agostini (fabio.agostini@roma2.infn.it) Dipartimento di Fisica, Università di Roma 'Tor Vergata' Via della Ricerca Scientifica 1, 00133 Roma Italy Giordano Cattani (giordano.cattani@roma2.infn.it) Dipartimento di Fisica, Università di Roma 'Tor Vergata' INFN sezione di Roma 'Tor Vergata' Via della Ricerca Scientifica 1, 00133 Roma Italy Luca Mazzaferro (luca.mazzaferro@roma2.infn.it) Dipartimento di Fisica, Università di Roma 'Tor Vergata' INFN sezione di Roma 'Tor Vergata' Via della Ricerca Scientifica 1, 00133 Roma Italy Marina Migliaccio (migliaccio@ifca.unican.es) Instituto de Fisica de Cantabria, Edificio Juan Jorda, Avenida de los Castros, E-39005 Santander, Cantabria Spain Davide Pietrobon (davide.pietrobon@jpl.nasa.gov) Jet Propulsion Laboratory - California Institute of Technology 4800 Oak Grove Drive 169-237 91109 Pasadena, CA USA Daniel Ricci Pacifici

  13. 75 FR 20370 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-04-19

    ... Cancer Institute Special Emphasis Panel, Assay Systems for Drug Efficacy in Cancer Stem Cells. Date..., Rockville, MD 20852. Contact Person: David G. Ransom, PhD, Scientific Review Officer, Research Programs... Domestic Assistance Program Nos. 93.392, Cancer Construction; 93.393, Cancer Cause and Prevention Research...

  14. 1st Roman Young Researchers Meeting Proceedings

    CERN Document Server

    Cannuccia, E; Pietrobon, D; Stellato, F; Veneziani, M

    2009-01-01

    During the last few decades scientists have been able to test the bases of the physics paradigms, where the quantum mechanics has to match the cosmological scales. Between the extremes of this scenario, biological phenomena and their complexity take place, challenging the laws we observe in the atomic and sub-atomic world. In order to explore the details of this world, new huge experimental facilities are under construction. These projects involve people coming from several countries and give physicists the opportunity to work together with chemists, biologists and other scientists. The Roman Young Researchers Meeting is a conference, organised by Ph. D. students and young postdocs connected to the Roman area. It is aimed primarily at graduate students and post-docs, working in physics. The 1st conference has been held on the 21st of July 2009 at the University of Roma Tor Vergata. It was organised in three sessions, devoted to Astrophysics and Cosmology, Soft and Condensed Matter Physics and Theoretical and ...

  15. Proceedings of the Department of Defense Breast Cancer Research Program Meeting for Era of Hope, Held in Baltimore, Maryland on 25-28 June 2008

    Science.gov (United States)

    2008-06-01

    Piper Cancer Center; and Scottsdale Healthcare. P5-15: REGRESSION ON MEDIAN RESIDUAL LIFE Jong-Hyeon Jeong,1 Sin-Ho Jung ,2 and Hanna Bandos1...a similar inhibitory archetype , antibody inhibitors provide an opportunity to develop divergent mechanisms of inhibition from a single scaffold... Jung Moon,1 Chuan-Yuan Li,2 Ines Batinic-Haberle,1 and Mark W. Dewhirst1 1Duke University Medical Center and 2University of Colorado Denver, Health

  16. Research Associate | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Basic Science Program (BSP) pursues independent, multidisciplinary research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics. Research efforts and support are an integral part of the Center for Cancer Research (CCR) at the Frederick National Laboratory for Cancer Research (FNLCR). KEY ROLES/RESPONSIBILITIES - Research Associate III Dr. Zbigniew Dauter is the head investigator of the Synchrotron Radiation Research Section (SRRS) of CCR’s Macromolecular Crystallography Laboratory. The Synchrotron Radiation Research Section is located at Argonne National Laboratory, Argonne, Illinois; this is the site of the largest U.S. synchrotron facility. The SRRS uses X-ray diffraction technique to solve crystal structures of various proteins and nucleic acids of biological and medical relevance. The section is also specializing in analyzing crystal structures at extremely high resolution and accuracy and in developing methods of effective diffraction data collection and in using weak anomalous dispersion effects to solve structures of macromolecules. The areas of expertise are: Structural and molecular biology Macromolecular crystallography Diffraction data collection Dr. Dauter requires research support in these areas, and the individual will engage in the purification and preparation of samples, crystallize proteins using various techniques, and derivatize them with heavy atoms/anomalous scatterers, and establish conditions for cryogenic freezing. Individual will also participate in diffraction data collection at the Advanced Photon Source. In addition, the candidate will perform spectroscopic and chromatographic analyses of protein and nucleic acid samples in the context of their purity, oligomeric state and photophysical properties.

  17. Nutritional Science Meetings and Events | Division of Cancer Prevention

    Science.gov (United States)

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  18. 2015 Materials Research Society Spring Meeting

    Science.gov (United States)

    2016-05-12

    13-18 doi: 10.1557/opl.2015.619, Published online by Cambridge University Press 17 Jun 2015 Breast cancer detection using charge sensors coupled to DNA...University, Jinan, China. Show Abstract 4:30 PM - GG9.09 Breast Cancer Detection using Charge Sensors Coupled to DNA Monolayer Marina Ribeiro...Abstract 4:15 PM - GG2.09 A Nanohybrid System Based on Holotransferrin and Maghemite Nanoparticles as a Promising Theranostic Device Miryana Hemadi1

  19. Prostate Cancer Research Training Program

    Science.gov (United States)

    2017-09-01

    the research program by each mentor will certainly produce important research findings, aided in part by the summer research of...our "translational" research in the form of clinical trials of our adenovirus vaccine in men with prostate cancer. Important in these trials is the ...epidemiology, and treatment. Living in Iowa City for the Summer Housing and Meals - All students will be housed in the one of the residence halls on the

  20. Cancer Trends: Influencing Care and Research Priorities

    Science.gov (United States)

    Many of the trends being seen in cancer are changing how we view cancer and how we address it, from prompting research to identify the underlying causes of cancers increasing in incidence to informing research on treatment and prevention.

  1. Meeting report: Metastasis Research Society-Chinese Tumor Metastasis Society joint conference on metastasis.

    Science.gov (United States)

    Bankaitis, Katherine; Borriello, Lucia; Cox, Thomas; Lynch, Conor; Zijlstra, Andries; Fingleton, Barbara; Gužvić, Miodrag; Anderson, Robin; Neman, Josh

    2017-04-01

    During September 16th-20th 2016, metastasis experts from around the world convened for the 16th Biennial Congress of the Metastasis Research Society and 12th National Congress of the Chinese Tumor Metastasis Society in Chengdu, China to share most current data covering basic, translational, and clinical metastasis research. Presentations of the more than 40 invited speakers of the main congress and presentations from the associated Young Investigator Satellite Meeting are summarized in this report by session topic. The congress program also included three concurrent short talk sessions, an advocacy forum with Chinese and American metastatic patient advocates, a 'Meet the Professors Roundtable' session for young investigators, and a 'Meet the Editors' session with editors from Cancer Cell and Nature Cell Biology. The goal of integrating expertise and exchanging the latest findings, ideas, and practices in cancer metastasis research was achieved magnificently, thanks to the excellent contributions of many leaders in the field.

  2. 76 FR 20693 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2011-04-13

    ... special assistance, such as sign language interpretation or other reasonable accommodations, should notify... Dialogue, Nonprofit Conveners Driving Implementation of Research Outcomes, Barriers to Implementation of Research Outcomes, Presentations Highlighting Local Academic Research in Cancer. Place: Rizzo Conference...

  3. Meeting

    Indian Academy of Sciences (India)

    At the invitation of the Physical Research. Laboratory, the 58th Annual Meeting of the. Academy was held at Ahmedabad from 6 to 9. November 1992. The meetings were held at the. Physical Research Laboratory (PRL) and the. Space Applications Centre (SAC) and were organized by PRl, in cooperation with ~AC, the.

  4. 77 FR 55848 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2012-09-11

    ... Clinical Trials and Strategic Planning Subcommittee. Date: September 24, 2012. Time: 5 p.m. to 6 p.m... Trials Strategic Planning Subcommittee. Dial in number: 1-866-652-9542 and Passcode: 4596704. Place... Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397...

  5. 78 FR 5190 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2013-01-24

    ... Clinical Trials and Strategic Planning Subcommittee. Date: February 25, 2013. Time: 5:00 p.m. to 6:00 p.m... Trials Strategic Planning Subcommittee. Dial in number: 1-866-652-9542 and Passcode: 4596704. Place... Research; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396...

  6. 77 FR 36564 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2012-06-19

    ... Prevention Method: State of the, Science and Evidence. Place: Hilton San Francisco Financial District, 750... applicable, the business or professional affiliation of the interested person. Information is also available... Research; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396...

  7. 78 FR 78467 - Connected Vehicle Research Program Public Meeting; Notice of Public Meeting

    Science.gov (United States)

    2013-12-26

    ... Meeting AGENCY: ITS Joint Program Office, Research and Innovative Technology Administration, U.S... Technology Administration (RITA) Connected Vehicle Systems. The meeting will take place Thursday, January 16, 2014, from 1:00 p.m. (EST) to 4:00 p.m. (EST) in the Hampton Room at the Omni Shoreham Hotel, 2500...

  8. 75 FR 55634 - National Research Advisory Council; Notice of Meeting

    Science.gov (United States)

    2010-09-13

    ... DEPARTMENT OF VETERANS AFFAIRS National Research Advisory Council; Notice of Meeting The Department of Veterans Affairs (VA) gives notice under Public Law 92-463 (Federal Advisory Committee Act... Phoenix Park Hotel, Federal City Room, 520 North Capitol Street, NW., Washington, DC. The meeting will...

  9. 2006 Fundamental Research Underlying Solid-State Lighting: Contractors Meeting

    Energy Technology Data Exchange (ETDEWEB)

    Fitzsimmons, Tim [Dept. of Energy (DOE), Washington, DC (United States). Office of Basic Energy Sciences. Division of Materials Sciences and Engineering; Kini, Arvind [Dept. of Energy (DOE), Washington, DC (United States). Office of Basic Energy Sciences. Division of Materials Sciences and Engineering; Kelley, Dick [Dept. of Energy (DOE), Washington, DC (United States). Office of Basic Energy Sciences. Division of Materials Sciences and Engineering

    2006-02-01

    This volume highlights the scientific content of the 2006 Fundamental Research Underlying Solid-State Lighting Contractors Meeting sponsored by the Division of Materials Sciences and Engineering (DMS&E) in the Office of Basic Energy Sciences (BES) of the U. S. Department of Energy (DOE). This meeting is the second in a series of research theme-based Contractors Meetings and will focus on BES/DMS&E-funded research that underpins solid-state lighting technology. The meeting will feature research that cuts across several DMS&E core research program areas. The major programmatic emphasis is on developing a fundamental scientific base, in terms of new concepts and new materials that could be used or mimicked in designing novel materials, processes or devices.

  10. XXXI LIAC Meeting on Vascular Research - Proceedings

    Directory of Open Access Journals (Sweden)

    L. Monteiro Rodrigues et al.

    2015-12-01

    Full Text Available LIAC MEETING ON VASCULAR RESEARCH 9 a 12 September | 9 a 12 Setembro Lisbon U. Lusofona's | Lisboa - Universidade Lusófona Scientific Commitee /Comissão Científica Luís Monteiro Rodrigues Philippe Charpiot, Brigida Bochicchio Alain-Pierre Gadeau Jacques Bonnet Julia Bujan Colette Lacabanne Fulvia Ortolani Organizing Commitee /Comissão Organizadora Luis Monteiro Rodrigues, CBIOS - ULHT Ana Sofia Fernandes, CBIOS - ULHT Catarina Pinto Reis, CBIOS - ULHT Henrique Silva, CBIOS - ULHT Hugo Ferreira, IBEB - FCUL Escola de Ciências e Tecnologias da Saúde (ECTS da U. Lusófona de Humanidades e Tecnologias ALIES – Associação Lusófona para o Desenvolvimento do Ensino e Investigação das Ciências da Saúde CBIOS – Centro de Investigação em Biociências e Tecnologias da Saúde Program /Programa 9 September | 9 de Setembro Open Session | Sessão de abertura António Tamburro Conference Lisboa's Wine & Cheese battle 10 September | 10 de Setembro 1st Session |Sessão 1 Molecular and Supramolecular Structure | Estrutura Molecular e Supramolecular Charmain | Moderador - Alain Pierre Gadeau Keynote lecture 1 | 1ª Conferência Keynote Speaker | Prelector Sylvie Ricard-Blum Free Comunications | Comunicações livres Speakers | Prelectores Brigida Bochicchio Vicenta Llorente-Cortés Zeinab El Dirani J Leal Monedero Keynote lecture 2 | 2ª Conferência Keynote Speaker | Prelector Valerie Samouillan Program /Programa (cont. 2st Session |Sessão 2 Cell Biology and Signaling | Biologia Celular e Sinalização Charmain | Moderador - Michel Spina Keynote lecture 3 | 3ª Conferência Keynote Speaker | Prelector Vicente Andrés Free Comunications | Comunicações livres Speakers | Prelectores Alain Gadeau Cristina Sena Filipe Paula Pascal Maurice 11 September | 11 de Setembro 3st Session |Sessão 3 Biomaterials and Tissue Engineering | Biomateriais e Engenharia de Tecidos Charmain | Moderador - Brigida Bochicchio Keynote lecture 4 | 4ª Confer

  11. Residential Energy Efficiency Research Planning Meeting Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2012-02-01

    This report summarizes key findings and outcomes from the U.S. Department of Energy's Building America Residential Energy Efficiency Research Planning meeting, held on October 28-29, 2011, in Washington, D.C.

  12. Meet you in the elevator! Pitching yourself and your research

    NARCIS (Netherlands)

    Scheffel, Maren; Börner, Dirk

    2013-01-01

    Scheffel, M., & Börner, D. (2013, 31 May). Meet you in the elevator! Pitching yourself and your research. Workshop presentation at the 9th Joint European Summer School on Technology Enhanced Learning, Limassol, Cyprus.

  13. Beyond the androgen receptor II: New approaches to understanding and treating metastatic prostate cancer; Report from the 2017 Coffey-Holden Prostate Cancer Academy Meeting.

    Science.gov (United States)

    Miyahira, Andrea K; Cheng, Heather H; Abida, Wassim; Ellis, Leigh; Harshman, Lauren C; Spratt, Daniel E; Simons, Jonathan W; Pienta, Kenneth J; Soule, Howard R

    2017-11-01

    The 2017 Coffey-Holden Prostate Cancer Academy (CHPCA) Meeting, "Beyond the Androgen Receptor II: New Approaches to Understanding and Treating Metastatic Prostate Cancer," was held in Carlsbad, California from June 14-17, 2017. The CHPCA is an annual scientific conference hosted by the Prostate Cancer Foundation (PCF) that is uniquely designed to produce extensive and constructive discussions on the most urgent and impactful topics concerning research into the biology and treatment of metastatic prostate cancer. The 2017 CHPCA Meeting was the 5th meeting in this annual series and was attended by 71 investigators focused on prostate cancer and a variety of other fields including breast and ovarian cancer. The discussions at the meeting were concentrated on topics areas including: mechanisms and therapeutic approaches for molecular subclasses of castrate resistant prostate cancer (CRPC), the epigenetic landscape of prostate cancer, the role of DNA repair gene mutations, advancing the use of germline genetics in clinical practice, radionuclides for imaging and therapy, advances in molecular imaging, and therapeutic strategies for successful use of immunotherapy in advanced prostate cancer. This article reviews the presentations and discussions from the 2017 CHPCA Meeting in order to disseminate this knowledge and accelerate new biological understandings and advances in the treatment of patients with metastatic prostate cancer. © 2017 Wiley Periodicals, Inc.

  14. Association between meeting the WCRF/AICR cancer prevention recommendations and colorectal cancer incidence: results from the VITAL cohort.

    Science.gov (United States)

    Hastert, Theresa A; White, Emily

    2016-11-01

    In 2007, the World Cancer Research Fund (WCRF) and American Institute for Cancer Research (AICR) published eight recommendations regarding body weight, physical activity, and dietary behaviors aimed at reducing cancer incidence worldwide. In this paper, we assess whether meeting the WCRF/AICR recommendations is associated with lower colorectal cancer (CRC) incidence; evaluate whether particular recommendations are most strongly associated with lower CRC incidence; and assess whether associations differ by sex. We operationalized six of the recommendations (related to body weight, physical activity, energy density, plant foods, red and processed meat, and alcohol) and examined their association with CRC incidence over 7.6 years of follow-up in the prospective VITamins And Lifestyle Study cohort. Participants included 66,920 adults aged 50-76 years at baseline (2000-2002) with no history of CRC and with complete data for the recommendations evaluated. Incident colorectal cancers (n = 546) were tracked through 2009. Compared with meeting no recommendations, meeting 1-3 recommendations was associated with 34-45 % lower CRC incidence, and meeting 4-6 was associated with 58 % lower incidence (95 % CI 34 %, 74 %) in fully adjusted analyses. The recommendations most strongly associated with lower CRC risk for women were related to body fatness and red and processed meat, while for men these were alcohol intake and red and processed meat. Differences by sex were statistically significant (p < 0.05) for the recommendations related to body weight and to alcohol. Meeting the WCRF/AICR recommendations, particularly those related to alcohol, body weight, and red and processed meat, could substantially reduce CRC incidence; however, associations differ by sex.

  15. Breast Cancer Research at NASA

    Science.gov (United States)

    1998-01-01

    NASA's Marshall Space Flight Center (MSFC) is sponsoring research with Bioreactors, rotating wall vessels designed to grow tissue samples in space, to understand how breast cancer works. This ground-based work studies the growth and assembly of human mammary epithelial cells (HMEC) from breast cancer susceptible tissue. Radiation can make the cells cancerous, thus allowing better comparisons of healthy vs. tunourous tissues. Here, two High-Aspect Ratio Vessels turn at about 12 rmp to keep breast tissue constructs suspended inside the culture media. Syringes allow scientists to pull for analysis during growth sequences. The tube in the center is a water bubbler that dehumidifies the air to prevent evaporation of the media and thus the appearance of destructive bubbles in the bioreactor.

  16. Opportunities During Early Life for Cancer Prevention: Highlights From a Series of Virtual Meetings With Experts

    Science.gov (United States)

    Holman, Dawn M.; Buchanan, Natasha D.

    2018-01-01

    Compelling evidence suggests that early life exposures can affect lifetime cancer risk. In 2014, the Centers for Disease Control and Prevention’s (CDC’s) Cancer Prevention Across the Lifespan Workgroup hosted a series of virtual meetings with select experts to discuss the state of the evidence linking factors during the prenatal period and early childhood to subsequent risk of both pediatric and adult cancers. In this article, we present the results from a qualitative analysis of the meeting transcripts and summarize themes that emerged from our discussions with meeting participants. Themes included the state of the evidence linking early life factors to cancer risk, research gaps and challenges, the level of evidence needed to support taking public health action, and the challenges of communicating complex, and sometimes conflicting, scientific findings to the public. Opportunities for collaboration among public health agencies and other stakeholders were identified during these discussions. Potential next steps for the CDC and its partners included advancing and building upon epidemiology and surveillance work, developing and using evidence from multiple sources to inform decision-making, disseminating and communicating research findings in a clear and effective way, and expanding collaborations with grantees and other partners. As the science on early life factors and cancer risk continues to evolve, there are opportunities for collaboration to translate science into actionable public health practice. PMID:27940972

  17. FUTURO REMOTO 2015: researchers meet people.

    Science.gov (United States)

    De Lucia, Maddalena; Fedele, Alessandro; Esposito, Roberta; Torello, Vincenzo; Nave, Rosella; Pino, Nicola Alessandro; Russo, Massimo; Alessio, Giuliana; Gaudiosi, Germana; Nappi, Rosa; Belviso, Pasquale; Carandente, Antonio; De Cesare, Walter; Sansivero, Fabio; Siniscalchi, Valeria; Borgstrom, Sven; Milano, Girolamo; Pasquale Ricciardi, Giovanni; De Natale, Giuseppe

    2016-04-01

    As participant of the 29th Edition of the cultural initiative "Futuro Remoto 2015", the INGV section of Naples Osservatorio Vesuviano has realized a temporary exhibition aimed to build bridges between the scientific community and the public. The event, a festival of art, culture, science and technology, has taken place on October 15th - 19th 2015, in Naples, Italy, in the city center, and was organized by "Città della Scienza", the science center of the city of Naples, belonging to the ECSITE netwok.. The total number of visitors was about 130.000 people. It was a free and open access event, funded by public institutions. Sharing their scientific expertise with the public, in the "Terra" ("Earth") stand the INGV-OV researchers have shown, with interactive labs, how progress in technology and research develope and allow a better understanding of the dynamic processes and of the evolution of our planet. Popularizing science, when widely accessible to the people, make the knowledge not remaining confined to an elite, being efficiently spread in society, with deep implications in the social role of researchers. Practical activities and labs, dialogues and interaction with researchers of INGV-OV have allowed young and adult public, schools, students, experts or simply curious people to deepen burning issues in an area exposed to high seismic and volcanic risk.

  18. 2010 Atmospheric System Research (ASR) Science Team Meeting Summary

    Energy Technology Data Exchange (ETDEWEB)

    Dupont, DL

    2011-05-04

    This document contains the summaries of papers presented in poster format at the March 2010 Atmospheric System Research Science Team Meeting held in Bethesda, Maryland. More than 260 posters were presented during the Science Team Meeting. Posters were sorted into the following subject areas: aerosol-cloud-radiation interactions, aerosol properties, atmospheric state and surface, cloud properties, field campaigns, infrastructure and outreach, instruments, modeling, and radiation. To put these posters in context, the status of ASR at the time of the meeting is provided here.

  19. Media | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The Office of Cancer Clinical Proteomics Research (OCCPR) is committed to providing the media with timely and accurate information.  This section offers key resources for patients, cancer researchers, physicians, and media professionals.

  20. Strengthening the Cancer Research Enterprise - Annual Plan

    Science.gov (United States)

    NCI's expanding infrastructure, support for scientists at every career stage, and funding of small business innovation enables discoveries that advance cancer research. Read more about how NCI is strenghtening the cancer research enterprise.

  1. International Partnerships for Clinical Cancer Research

    Science.gov (United States)

    CGH co-sponsors the 2015 International Symposium on Cancer Clinical Trials and related meetings held in partnership with the Japanese National Cancer Center (JNCC) and Embassies of France, Korea, United Kingdom (UK), and United States (US) in Tokyo on May 14 - 15, 2015.

  2. Expert Meeting Report: Advanced Envelope Research for Factory Built Housing

    Energy Technology Data Exchange (ETDEWEB)

    Levy, E.; Mullens, M.; Tompos, E.; Kessler, B.; Rath, P.

    2012-04-01

    This report provides information about the Building America expert meeting on advanced envelope research for factory built housing, hosted by the ARIES Collaborative on October 11, 2011, in Phoenix, Arizona. The goals of this meeting were to provide a comprehensive solution to the use of three previously selected advanced alternatives for factory-built wall construction, assess each option focusing on major issues relating to viability and commercial potential, and determine additional steps are required to reach this potential.

  3. Expert Meeting Report: Advanced Envelope Research for Factory Built Housing

    Energy Technology Data Exchange (ETDEWEB)

    Levy, E.; Mullens, M.; Tompos, E.; Kessler, B.; Rath, P.

    2012-04-01

    This report provides information about the expert meeting on advanced envelope research for factory built housing, hosted by the ARIES Collaborative on October 11, 2011, in Phoenix, Arizona. The goals of this meeting were to provide a comprehensive solution to the use of three previously selected advanced alternatives for factory-built wall construction, assess each option focusing on major issues relating to viability and commercial potential, and determine additional steps are required to reach this potential.

  4. Thirteenth water reactor safety research information meeting: proceedings Volume 1

    International Nuclear Information System (INIS)

    Weiss, A.J.

    1986-02-01

    This six-volume report contains 151 papers out of the 178 that were presented at the Thirteenth Water Reactor Safety Research Information Meeting held at the National Bureau of Standards, Gaithersburg, Maryland, during the week of October 22-25, 1985. The papers are printed in the order of their presentation in each session and describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included thirty-one different papers presented by researchers from Japan, Canada and eight European countries. The title of the papers and the names of the authors have been updated and may differ from those that appeared in the final program of the meeting. This volume presents information on: risk analysis PRA application; severe accident sequence analysis; risk analysis/dependent failure analysis; and industry safety research

  5. 78 FR 25691 - Meeting Notice of the National Agricultural Research, Extension, Education, and Economics...

    Science.gov (United States)

    2013-05-02

    ... Meeting Notice of the National Agricultural Research, Extension, Education, and Economics Advisory Board AGENCY: Research, Education, and Economics, USDA. ACTION: Notice of meeting. SUMMARY: In accordance with...) announces a meeting of the National Agricultural Research, Extension, Education, and Economics Advisory...

  6. Presentations at the seventh Danish marine research meeting

    International Nuclear Information System (INIS)

    1993-01-01

    This report presents contributions from the 7th Danish marine research meeting, arranged by the Danish National Oceanologic Board the 21-24 Jan 1992 in the new Marine Geology Research centre of the Aarhus University. 310 participants presented 76 lectures and 35 posters in the field of marine geology, hydrology, biology contamination monitoring etc. (EG)

  7. Proceedings of the meeting on large scale computer simulation research

    International Nuclear Information System (INIS)

    2004-04-01

    The meeting to summarize the collaboration activities for FY2003 on the Large Scale Computer Simulation Research was held January 15-16, 2004 at Theory and Computer Simulation Research Center, National Institute for Fusion Science. Recent simulation results, methodologies and other related topics were presented. (author)

  8. In Absentia: An Exploratory Study of How Patients Are Considered in Multidisciplinary Cancer Team Meetings.

    Science.gov (United States)

    Hahlweg, Pola; Hoffmann, Jana; Härter, Martin; Frosch, Dominick L; Elwyn, Glyn; Scholl, Isabelle

    2015-01-01

    Multidisciplinary team meetings and shared decision-making are potential means of delivering patient-centred care. Not much is known about how those two paradigms fit together in cancer care. This study aimed to investigate how decisions are made in multidisciplinary team meetings and whether patient perspectives are incorporated in these decisions. A qualitative study was conducted using non-participant observation at multidisciplinary team meetings (also called tumor boards) at the University Cancer Center Hamburg-Eppendorf, Germany. Two researchers recorded structured field notes from a total of N = 15 multidisciplinary team meetings. Data were analyzed using content analysis and descriptive statistics. Physicians mainly exchanged medical information and based their decision-making on this information. Individual patient characteristics or their treatment preferences were rarely considered or discussed. In the few cases where patient preferences were raised as a topic, this information did not seem to be taken into account in decision-making processes about treatment recommendations. The processes in multidisciplinary team meetings we observed did not exhibit shared decision-making. Patient perspectives were absent. If multidisciplinary team meetings wish to become more patient-centred they will have to modify their processes and find a way to include patient preferences into the decision-making process.

  9. Administrative Assistant | Center for Cancer Research

    Science.gov (United States)

    We are looking for a pleasant, organized, dependable person to serve as an administrative assistant at the National Cancer Institute on the campus of the National Institutes of Health (NIH).  Work supports a busy clinical program in the world’s largest dedicated research hospital patients call the “House of Hope.”  Tasks involve calendar management, arranging travel, scheduling conferences and meetings, drafting and handling correspondence, timekeeping, placing purchase requests, office property management, greeting visitors, and office work, such as copying, filing, and scanning.  Ability to work with basic computer office software (such as Word, Excel, and PowerPoint) required. Some administrative experience, including calendar management preferred.  Full-time position, business hours. NIH is metro accessible.

  10. Research using small tokamaks. Proceedings of a technical committee meeting

    International Nuclear Information System (INIS)

    1997-09-01

    The technical reports in these proceedings were presented at the IAEA Technical Committee Meeting on research Using Small Tokamaks, held in Ahmedabad, India, 6-7 December 1995. The purpose of this annual meeting is to provide a forum for the exchange of information on various small and medium sized plasma experiments, not only for tokamaks. The potential benefits of these research programmes are to: test theories, such as effects of the plasma rotation; check empirical scalings, such as density limits; develop fusion technology hardware; develop plasma diagnostics; such as tomography; and to train scientists, engineers, technicians, and students, particularly in developing IAEA Member States

  11. Meeting

    Indian Academy of Sciences (India)

    The organization and arrangements for the scientific meetings, cultural event and the visits to Lothal and SAC were superb. The Academy is grateful to the Physical Research Laboratory particularly R K Varma, Director, PRL, to the. Institute for Plasma Research and its Director. P K Kaw, to the Space Applications Centre and.

  12. Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

    Science.gov (United States)

    The Nutritional Science Research Group in the Division of Cancer Prevention at the National Cancer Institute, National Institutes of Health and the Department of Nutrition at the Clinical Center, National Institutes of Health are offering a one week educational opportunity in "Nutrition and Cancer Prevention Research" for individuals with a sustained commitment to nutrition

  13. Big Data-Led Cancer Research, Application, and Insights.

    Science.gov (United States)

    Brown, James A L; Ni Chonghaile, Triona; Matchett, Kyle B; Lynam-Lennon, Niamh; Kiely, Patrick A

    2016-11-01

    Insights distilled from integrating multiple big-data or "omic" datasets have revealed functional hierarchies of molecular networks driving tumorigenesis and modifiers of treatment response. Identifying these novel key regulatory and dysregulated elements is now informing personalized medicine. Crucially, although there are many advantages to this approach, there are several key considerations to address. Here, we examine how this big data-led approach is impacting many diverse areas of cancer research, through review of the key presentations given at the Irish Association for Cancer Research Meeting and importantly how the results may be applied to positively affect patient outcomes. Cancer Res; 76(21); 6167-70. ©2016 AACR. ©2016 American Association for Cancer Research.

  14. American Institute for Cancer Research

    Science.gov (United States)

    INFOGRAPHICS RECIPES FOODS THAT FIGHT CANCER SHOP Donate Now Planned Giving Memorial Gifts Car Donations Home Reduce Your Cancer Risk Diet How healthy is your diet? A cancer-protective diet Healthy recipes Nutrition facts Phytochemicals in ...

  15. Gynecologic Cancer InterGroup (GCIG) endometrial cancer clinical trials planning meeting: taking endometrial cancer trials into the translational era.

    NARCIS (Netherlands)

    Creutzberg, C.L.; Kitchener, H.C.; Birrer, M.J.; Landoni, F.; Lu, K.H.; Powell, M.; Aghajanian, C.; Edmondson, R.; Goodfellow, P.J.; Quinn, M.; Salvesen, H.B.; Thomas, G; Ottevanger, N.; et al.,

    2013-01-01

    OBJECTIVE: The second Gynecologic Cancer InterGroup (GCIG) Endometrial Cancer Clinical Trials Planning Meeting was held on December 1, 2012, and included international multidisciplinary representatives of the 24 member groups. The aims were to review recent advances in molecular pathology of

  16. Research information meets research data management … in the library?

    Directory of Open Access Journals (Sweden)

    Anna Clements

    2013-11-01

    Full Text Available Research data management (RDM is a major priority for many institutions as they struggle to cope with the plethora of pronouncements including funder policies, a G8 statement, REF2020 consultations, all stressing the importance of open data in driving everything from global innovation through to more accountable governance; not to mention the more direct possibility that non-compliance could result in grant income drying up. So, at the coalface, how do we become part of this global movement? In this article the author explains the approach being taken at the University of St Andrews, building on the research information management infrastructure (data, systems and people that has evolved since 2006. Continuing to navigate through the rapidly evolving research policy and cultural landscape, they aim to establish services to support their research community as it moves to this ‘open by default’ requirement of funders and governments.

  17. Meeting Report of the Fifth International Cancer Epigenetics Conference in Beijing, China, October 2016.

    Science.gov (United States)

    Gao, Dan; Herman, James G; Cui, Hengmi; Jen, Jin; Fuks, Francois; Brock, Malcolm V; Ushijima, Toshikazu; Croce, Carlo; Akiyama, Yoshimitsu; Guo, Mingzhou

    2017-07-01

    Fifth International Cancer Epigenetics Conference, Beijing, China, 21-23 October 2016 This meeting reported many new findings in the field of cancer epigenetics, including basic science, translational and clinical studies. In this report, we summarize some of the main advancements and prospects in cancer epigenetics presented at this meeting.

  18. Dr. Ted Trimble: Why I Do Cancer Research

    Science.gov (United States)

    In a video, Dr. Ted Trimble talks about the importance of cancer research. World Cancer Research Day commemorates the important role research and cancer researchers play in reducing the global burden of cancer.

  19. Research in Danish cancer rehabilitation

    DEFF Research Database (Denmark)

    Høybye, Mette Terp; Dalton, Susanne Oksbjerg; Christensen, Jane

    2008-01-01

    Worldwide, the number of cancer survivors is increasing, owing to improvements in cancer therapy, resulting in an increased need to address the physical and mental sequelae of cancer. This paper introduces a Danish psychosocial cancer intervention and presents the baseline characteristics...

  20. A New Phase in Cancer Research at CERN

    CERN Multimedia

    2002-01-01

    The first meeting of the ENLIGHT network, set up to co-ordinate the development of light ion cancer therapy projects in Europe, took place at CERN last week. This is a form of therapy ideally suited to the treatment of deep-seated tumours and those near critical organs. Hans Hoffmann, Director for Technology transfer and scientific computing, and Director General Luciano Maiani during the opening of the first meeting of the ENLIGHT network that was held at CERN last week. The fruit of several years of work, this meeting offers new hope for the treatment of certain types of cancer. Around 70 specialists, including radiotherapists, oncologists, physicists and engineers, got together at CERN for the first meeting of a European cancer therapy research network named ENLIGHT (European Network for research in LIGHt ion Therapy(1)). This initiative, headed by oncologists and funded by the European Commission, aims to promote the development of light ion (hadron) therapy projects. The choice of CERN as a venue for ...

  1. Basic research on cancer related to radiation associated medical researches

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong In; Hwang, Dae Yong; Bang, Ho Yoon [and others

    2000-12-01

    Basic Research on Cancer related to Radiation Associated Medical Researches including 1. Establishment of animal model of colorectal cancer liver metastasis and measurement of angiogenesis, 2. Tissue expression of Tie-1 and Tie-2 in human colorectal cancer, 3. Enhancement of G2/Mphase Cell Fraction by Adenovirus-mediated p53 Gene Transfer in Ovarian Cancer Cell Lines, 4. Clinical Characteristics of the patients with Non-B Non-C Hepatocellular Carcinoma and Frequency of HBV, HCV and TTV Viremia in these Patients, 5. Significance of serum iron and ferritin in patients with stomach cancer, 6. Telomerase assay for early detection of lung cancer, 7. Study on the Usefulness of Aldehyde dehydrogenase-2 Genotyping for Risk Group of Alcohol-related Cancer Screening, 8. Gene therapy using hepatoma specific promoter, 9. Study on the Influence of DNA repair gene, XRCC1 Genotypes on the Risk of Head and Neck Cancer were performed.

  2. Basic research on cancer related to radiation associated medical researches

    International Nuclear Information System (INIS)

    Lee, Jong In; Hwang, Dae Yong; Bang, Ho Yoon

    2000-12-01

    Basic Research on Cancer related to Radiation Associated Medical Researches including 1. Establishment of animal model of colorectal cancer liver metastasis and measurement of angiogenesis, 2. Tissue expression of Tie-1 and Tie-2 in human colorectal cancer, 3. Enhancement of G2/Mphase Cell Fraction by Adenovirus-mediated p53 Gene Transfer in Ovarian Cancer Cell Lines, 4. Clinical Characteristics of the patients with Non-B Non-C Hepatocellular Carcinoma and Frequency of HBV, HCV and TTV Viremia in these Patients, 5. Significance of serum iron and ferritin in patients with stomach cancer, 6. Telomerase assay for early detection of lung cancer, 7. Study on the Usefulness of Aldehyde dehydrogenase-2 Genotyping for Risk Group of Alcohol-related Cancer Screening, 8. Gene therapy using hepatoma specific promoter, 9. Study on the Influence of DNA repair gene, XRCC1 Genotypes on the Risk of Head and Neck Cancer were performed

  3. Review of the 25th annual scientific meeting of the International Society for Biological Therapy of Cancer

    Directory of Open Access Journals (Sweden)

    Jaffee Elizabeth M

    2011-05-01

    Full Text Available Abstract Led by key opinion leaders in the field, the 25th Annual Meeting of the International Society for Biological Therapy of Cancer (iSBTc, recently renamed the Society for Immunotherapy of Cancer, SITC provided a scientific platform for ~500 attendees to exchange cutting-edge information on basic, clinical, and translational research in cancer immunology and immunotherapy. The meeting included keynote addresses on checkpoint blockade in cancer therapy and recent advances in therapeutic vaccination against cancer induced by Human Papilloma Virus 16. Participants from 29 countries interacted through oral presentations, panel discussions, and posters on topics that included dendritic cells and cancer, targeted therapeutics and immunotherapy, innate/adaptive immune interplay in cancer, clinical trial endpoints, vaccine combinations, countering negative regulation, immune cell trafficking to tumor microenvironment, and adoptive T cell transfer. In addition to the 50 oral presentations and >180 posters on these topics, a new SITC/iSBTc initiative to create evidence-based Cancer Immunotherapy Guidelines was announced. The SITC/iSBTc Biomarkers Taskforce announced the release of recommendations on immunotherapy biomarkers and a highly successful symposium on Immuno-Oncology Biomarkers that took place on the campus of the National Institutes of Health (NIH immediately prior to the Annual Meeting. At the Annual Meeting, the NIH took the opportunity to publicly announce the award of the U01 grant that will fund the Cancer Immunotherapy Trials Network (CITN. In summary, the Annual Meeting gathered clinicians and scientists from academia, industry, and regulatory agencies from around the globe to interact and exchange important scientific advances related to tumor immunobiology and cancer immunotherapy.

  4. Report of the Second Asian Prostate Cancer (A-CaP Study Meeting

    Directory of Open Access Journals (Sweden)

    Choung-Soo Kim

    2017-09-01

    Full Text Available The Asian Prostate Cancer (A-CaP Study is an Asia-wide initiative that has been developed over the course of 2 years. The study was launched in December 2015 in Tokyo, Japan, and the participating countries and regions engaged in preparations for the study during the course of 2016, including patient registration and creation of databases for the purpose of the study. The Second A-CaP Meeting was held on September 8, 2016 in Seoul, Korea, with the participation of members and collaborators from 12 countries and regions. Under the study, each participating country or region will begin registration of newly diagnosed prostate cancer patients and conduct prognostic investigations. From the data gathered, common research themes will be identified, such as comparisons among Asian countries of background factors in newly diagnosed prostate cancer patients. This is the first Asia-wide study of prostate cancer and has developed from single country research efforts in this field, including in Japan and Korea. At the Second Meeting, participating countries and regions discussed the status of preparations and discussed various issues that are being faced. These issues include technical challenges in creating databases, promoting participation in each country or region, clarifying issues relating to data input, addressing institutional issues such as institutional review board requirements, and the need for dedicated data managers. The meeting was positioned as an opportunity to share information and address outstanding issues prior to the initiation of the study. In addition to A-CaP-specific discussions, a series of special lectures was also delivered as a means of providing international perspectives on the latest developments in prostate cancer and the use of databases and registration studies around the world.

  5. Strategies to improve the efficiency and utility of multidisciplinary team meetings in urology cancer care: a survey study.

    Science.gov (United States)

    Lamb, Benjamin W; Jalil, Rozh T; Sevdalis, Nick; Vincent, Charles; Green, James S A

    2014-09-08

    The prevalence of multidisciplinary teams (MDT) for the delivery of cancer care is increasing globally. Evidence exists of benefits to patients and healthcare professionals. However, MDT working is time and resource intensive. This study aims to explore members' views on existing practices of urology MDT working, and to identify potential interventions for improving the efficiency and productivity of the MDT meeting. Members of urology MDTs across the UK were purposively recruited to participate in an online survey. Survey items included questions about the utility and efficiency of MDT meetings, and strategies for improving the efficiency of MDT meetings: treating cases by protocol, prioritising cases, and splitting the MDT into subspeciality meetings. 173 MDT members participated (Oncologists n = 77, Cancer Nurses n = 54, Urologists n = 30, other specialities n = 12). 68% of respondents reported that attending the MDT meeting improves efficiency in care through improved clinical decisions, planning investigations, helping when discussing plans with patients, speciality referrals, documentation/patient records. Participants agreed that some cases including low risk, non-muscle invasive bladder cancer and localised, low-grade prostate cancer could be managed by pre-agreed pathways, without full MDT review. There was a consensus that cases at the MDT meeting could be prioritised by complexity, tumour type, or the availability of MDT members. Splitting the MDT meeting was unpopular: potential disadvantages included loss of efficiency, loss of team approach, unavailability of members and increased administrative work. Key urology MDT members find the MDT meeting useful. Improvements in efficiency and effectiveness may be possible by prioritising cases or managing some low-risk cases according to previously agreed protocols. Further research is needed to test the effectiveness of such strategies on MDT meetings, cancer care pathways and patient outcomes in clinical

  6. Proceedings of the black liquor research program review fifth meeting

    Energy Technology Data Exchange (ETDEWEB)

    1988-09-01

    On June 14--17, 1988 the participants and invited guests of the Cooperative Program in Kraft Recovery gathered in Charleston, South Carolina, to review progress on four major black liquor research programs being executed at the Institute of Paper Chemistry, the University of Maine, the National Bureau of Standards, and the University of Florida. These programs include: (1) Black Liquor Properties; (2) Black Liquor Droplet Formation; (3) Black Liquor Nozzle Evaluation; and (4) Black Liquor Combustion. In addition to the objectives of previous meetings, this meeting made a direct attempt to gather ideas on how to improve our ability to move from new technology concepts to commercial implementation. Also attached is the agenda for the Charleston meeting. The first two days were involved with updates and reviews of the four major black liquor programs. A half day was spent discussing pathways to implementation and developing thoughts on what industry, DOE and academia could do to facilitate commercial implementation of the research results. This publication is a summary of the presentations made in Charleston and the industry responses to the research work. Readers are cautioned that the contents are in-progress updates on the status of the research and do not represent referred technical papers. Any questions regarding the content should be referred to the principal investigators of the project.

  7. Fundamental Science with Pulsed Power: Research Opportunities and User Meeting.

    Energy Technology Data Exchange (ETDEWEB)

    Mattsson, Thomas Kjell Rene [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Wootton, Alan James [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sinars, Daniel Brian [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Spaulding, Dylan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Winget, Don [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-10-01

    The fifth Fundamental Science with Pulsed Power: Research Opportunities and User Meeting was held in Albuquerque, NM, July 20-­23, 2014. The purpose of the workshop was to bring together leading scientists in four research areas with active fundamental science research at Sandia’s Z facility: Magnetized Liner Inertial Fusion (MagLIF), Planetary Science, Astrophysics, and Material Science. The workshop was focused on discussing opportunities for high-­impact research using Sandia’s Z machine, a future 100 GPa class facility, and possible topics for growing the academic (off-Z-campus) science relevant to the Z Fundamental Science Program (ZFSP) and related projects in astrophysics, planetary science, MagLIF- relevant magnetized HED science, and materials science. The user meeting was for Z collaborative users to: a) hear about the Z accelerator facility status and plans, b) present the status of their research, and c) be provided with a venue to meet and work as groups. Following presentations by Mark Herrmann and Joel Lash on the fundamental science program on Z and the status of the Z facility where plenary sessions for the four research areas. The third day of the workshop was devoted to breakout sessions in the four research areas. The plenary-­ and breakout sessions were for the four areas organized by Dan Sinars (MagLIF), Dylan Spaulding (Planetary Science), Don Winget and Jim Bailey (Astrophysics), and Thomas Mattsson (Material Science). Concluding the workshop were an outbrief session where the leads presented a summary of the discussions in each working group to the full workshop. A summary of discussions and conclusions from each of the research areas follows and the outbrief slides are included as appendices.

  8. Prostate Cancer Research Training Program

    Science.gov (United States)

    2014-05-01

    how chromatin structure participates in the transcriptional regulation of cancer related genes including oncogenes and tumor suppressor genes...signaling pathways related to cancer progression to various approaches for therapeutic intervention in these pathways including large molecule...diseases, focused on molecular epidemiology, HPV effects on the development of genital and other cancers ; hormones and risk of HPV detection and

  9. Lysyl oxidase in cancer research

    DEFF Research Database (Denmark)

    Perryman, Lara; Erler, Janine Terra

    2014-01-01

    Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target. In this review we...

  10. Biorepository for Pediatric Cancer with Minimal Resources: Meeting the Challenges.

    Science.gov (United States)

    Labib, Rania M; Mostafa, Mahmoud M; Alfaar, Ahmad S; Yehia, Doaa; Alaa, Maram; Elzayat, Mariam G; Adel, Mohamed; Ezzat, Sameera; Abo El-Naga, Sherif

    2016-02-01

    Conducting high throughput -omics research requires high quality, data-rich biospecimens to unravel factors underlying childhood cancers; this is an extra burden in a limited resources country. For this purpose, Children's Cancer Hospital (CCHE), the largest pediatric cancer hospital worldwide, established a cutting-edge Biorepository and Biospecimen Research Facility (CCHE-BBR). To present a step-by-step guide to establishing a hospital-based biorepository with limited resources, and working in collaboration with different hospital facilities to supply the research community with high quality data-rich biospecimens fit for a wide range of research purposes. This approach will foster research in the era of personalized precision medicine. CCHE-IRB approved the collection and storage of biospecimens from patients and parents for future research. We focused on staff training, recruiting qualified scientists, and establishing the infrastructure. The CCHE Biorepository developed strict standardized procedures for sample acquisition, processing, annotation, storage, and distribution based on ISBER Best Practices and CAP-accreditation guidelines. We collect samples at different clinical time points (e.g., at remission and/or relapse) as well as parents' samples for genetic studies. Using CaTissue®, an electronic storage management system, allowed sample annotation and full integration with clinical data and the cancer registry. In 2 years, we succeeded in establishing a well-designed biorepository within our regulations, bylaws, and SOPs, and with a minimal budget. We store high quality blood derivatives, CSF, and malignant/normal tissue samples. Building a high quality biorepository with minimal-resources to encourage research is possible. Having the suitable infrastructure with a significant number of clinically annotated samples can play a major role in international research projects, sharing samples and/or data with other groups.

  11. Proceedings of the specialist research meetings on semiconductors with research reactors

    International Nuclear Information System (INIS)

    Kawakubo, Tetsuya; Kimura, Itsuro

    1987-01-01

    The meeting was proceeded divided five sessions, (I) structure analysis of semiconductors with neutrons, (II) structure analysis with positrons, (III) neutron transmutation doping and radiation damage, (IV) discussion on the way of research on semiconductors in the Institute. (author)

  12. Physician Assistant | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  13. Correlates of meeting the combined and independent aerobic and strength exercise guidelines in hematologic cancer survivors.

    Science.gov (United States)

    Vallerand, James R; Rhodes, Ryan E; Walker, Gordon J; Courneya, Kerry S

    2017-03-28

    Most previous research on the correlates of physical activity has examined the aerobic or strength exercise guidelines separately. Such an approach does not allow an examination of the correlates of meeting the combined guidelines versus a single guideline, or one guideline versus the other. Here, we report the prevalence and correlates of meeting the combined and independent exercise guidelines in hematologic cancer survivors (HCS). In a population-based, cross-sectional survey of 606 HCS from Alberta, Canada using a mailed questionnaire, we obtained separate assessments of aerobic and strength exercise behaviors, as well as separate assessments for motivations, regulations, and reflective processes using the multi-process action control framework (M-PAC). Overall, 22% of HCS met the combined exercise guideline, 22% met aerobic-only, 10% met strength-only, and 46% met neither exercise guideline. HCS were more likely to meet the combined guideline over the aerobic-only guideline if they had no children living at home, and over both the aerobic and strength-only guidelines if they had completed university. As hypothesized, those meeting the combined guideline also had a more favorable strength-specific M-PAC profile (i.e., motivations, regulations, and reflective processes) than those meeting the aerobic-only guideline, and a more favorable aerobic-specific M-PAC profile than those meeting the strength-only guideline. Interestingly and unexpectedly, HCS meeting the combined guidelines also reported significantly greater aerobic-specific perceived control, planning, and obligation/regret than those meeting the aerobic-only guideline, and greater strength-specific perceived control, planning, and obligation/regret than those meeting the strength-only guideline. Few HCS are meeting the combined exercise guidelines. M-PAC based variables are strong correlates of meeting the combined guidelines compared to aerobic or strength only guidelines. Strategies to help HCS meet

  14. 76 FR 76981 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-12-09

    ... Cancer Institute Special Emphasis Panel, Nanotechnology Reformulations for Cancer Drugs. Date: April 12... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel, NCI SPORE in Prostate and Gastrointestinal Cancers. Date...

  15. Predoctoral Training Program in Breast Cancer Research

    National Research Council Canada - National Science Library

    Stern, David F

    2004-01-01

    .... This means that research on breast cancer has finally advanced to the stage where a concentrated effort in translational research will yield great strides in detection, diagnosis, and treatment...

  16. Cancer Biotechnology | Center for Cancer Research

    Science.gov (United States)

    Biotechnology advances continue to underscore the need to educate NCI fellows in new methodologies. The Cancer Biotechnology course will be held on the NCI-Frederick campus on January 29, 2016 (Bldg. 549, Main Auditorium) and the course will be repeated on the Bethesda campus on February 9, 2016 (Natcher Balcony C). The latest advances in DNA, protein and image analysis will be presented. Clinical and postdoctoral fellows who want to learn about new biotechnology advances are encouraged to attend this course.

  17. Consumer involvement in cancer research: example from a Cancer Network.

    Science.gov (United States)

    Arain, Mubashir; Pyne, Sarah; Thornton, Nigel; Palmer, Susan; Sharma, Ricky A

    2015-10-01

    The involvement of consumers and the general public in improving cancer services is an important component of health services. However, consumer involvement in cancer research is relatively unexplored. The objective of this study was to explore different ways of involving consumers in cancer research in one regional network. Thames Valley Cancer Network Consumer Research Partnership (CRP) group was formed in 2009. The group consists of consumers and professionals to help in promoting consumer involvement in Cancer Research in the Thames Valley. This study evaluated the project of consumer involvement in cancer research in the Thames Valley from March 2010 to March 2011. We used different indices to judge the level of consumer involvement: number of projects involving consumers through the group, types of projects, level of involvement (ranged from consultation on research documents to collaborating in preparing grant applications) and the methods of involving consumers in cancer research. Fifteen projects were submitted to the CRP group during the 12-month period studied. Of these, eight projects were clinical trials, three were qualitative research projects, two were patients' surveys and two were non-randomized interventional studies. Seven projects requested consumer involvement on patient information sheets for clinical trials. Of these seven applications, three also requested consumers' help in designing research questionnaires and another three requested that consumers should be involved in their project management group. In addition, four projects involved consumers in the proposal development phase and another four projects asked for advice on how to increase trial recruitment, conduct patient interviews or help with grant applications. The creation of the CRP and this audit of its activity have documented consumer involvement in cancer research in the Thames Valley. We have clearly shown that consumers can be involved in designing and managing cancer

  18. Protocol Coordinator | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the consid erable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  19. Patient Care Coordinator | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  20. Researching the experience of kidney cancer patients.

    Science.gov (United States)

    Taylor, K

    2002-09-01

    The author's personal experience as a kidney cancer patient, researcher and founder of a kidney cancer support group forms the basis for consideration of the challenges involved in researching patients' experiences. The researcher needs to understand the variability of those experiences in both clinical and psychological-emotional terms, and in relation to the personal, familial and social contexts of the patient. It is also essential to define the purpose of the research and to show how an understanding of personal experiences of cancer can be used to enhance the quality of care for cancer patients. The research encounter with a patient is also in some respects a therapeutic encounter requiring a considerable degree of sensitivity on the part of the researcher. The person-centred approach of Carl Rogers is of value in supporting such an encounter.

  1. Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention

    Science.gov (United States)

    In response to a series of controversial articles about nutritional epidemiology and cancer published in 2014, staff from the Environmental Epidemiology Branch initiated a series of meetings to refine programmatic priorities for human nutrition/physical activity and cancer etiology research in the near term.

  2. 76 FR 576 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-05

    ... Committee: National Cancer Institute Special Emphasis Panel; Nanotechnology Sensing Platforms. Date: March 2... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel; SPORE in Mesothelioma, Lung, Breast and Ovarian Cancers. Date...

  3. NCI Cancer Research Data Ecosystem

    Science.gov (United States)

    An infographic explaining NCI’s present and future efforts to promote a culture of sharing data—clinical, genomic, proteomic, imaging, patient histories, and outcomes data—among stakeholders to impact cancer care.

  4. Surge in Philanthropy Fuels Cancer Research.

    Science.gov (United States)

    2017-01-01

    Philanthropy could lead to faster cures by funding riskier research-projects more likely to fail but with potentially high impact-and promoting better teamwork among researchers. However, researchers and fundraisers say that it should augment, not replace, government funding. ©2017 American Association for Cancer Research.

  5. Report of the research co-ordination meeting on labelling techniques of biomolecules for targeted radiotherapy

    International Nuclear Information System (INIS)

    2000-01-01

    The CRP's focus is on the preparation of site-specific radiopharmaceuticals labelled with β-emitters for the treatment of cancer. The radiopharmaceuticals should be designed in such a way to deliver the therapeutic doses with high specificity to tumour sites and with minimum dose to other organs. The 2. Research Co-ordination Meeting (RCM) took place in Mumbai, India from 31 January to 4 February 2000. The present report includes the results of all the participants including the report of the participant from Pakistan who could not attend the meeting. During the second RCM, three main aspects were dealt with viz. the different therapeutic isotopes studied, different carrier molecules like peptides and antibody and the biological aspects of these preparations

  6. Report of the research co-ordination meeting on labelling techniques of biomolecules for targeted radiotherapy

    International Nuclear Information System (INIS)

    2000-01-01

    The CRP's focus is on the preparation of site-specific radiopharmaceuticals labelled with with β - emitters for the treatment of cancer. The radiopharmaceuticals should be designed in such a way to deliver the therapeutic doses with high specificity to tumour sites and with minimum dose to other organs. The 2nd Research Co-ordination Meeting (RCM) took place in Mumbai, India from 31 January to 4 February 2000. The present report includes the results of all the participants including the report of the participant from Pakistan who could not attend the meeting. During the second RCM, three main aspects were dealt with viz. the different therapeutic isotopes studied, different carrier molecules like peptides and antibody and the biological aspects of these preparations

  7. Behavioral Research in Cancer Prevention and Control

    Science.gov (United States)

    Klein, William M. P.; Bloch, Michele; Hesse, Bradford W.; McDonald, Paige G.; Nebeling, Linda; O’Connell, Mary E.; Riley, William T.; Taplin, Stephen H.; Tesauro, Gina

    2013-01-01

    Human behavior is central to the etiology and management of cancer outcomes and presents several avenues for targeted and sustained intervention. Psychosocial experiences such as stress and health behaviors including tobacco use, sun exposure, poor diet, and a sedentary lifestyle increase the risk of some cancers yet are often quite resistant to change. Cancer screening and other health services are misunderstood and over-utilized, and vaccination underutilized, in part because of the avalanche of information about cancer prevention. Coordination of cancer care is suboptimal, and only a small fraction of cancer patients enroll in clinical trials essential to the development of new cancer treatments. A growing population of cancer survivors has necessitated a fresh view of cancer as a chronic rather than acute disease. Fortunately, behavioral research can address a wide variety of key processes and outcomes across the cancer controbiol continuum from prevention to end-of-life care. Here we consider effects at the biobehavioral and psychological, social and organizational, and environmental levels. We challenge the research community to address key behavioral targets across all levels of influence, while taking into account the many new methodological tools that can facilitate this important work. PMID:24512871

  8. Databases and QSAR for Cancer Research

    Directory of Open Access Journals (Sweden)

    Adeel Malik

    2006-01-01

    Full Text Available In this review, we take a survey of bioinformatics databases and quantitative structure-activity relationship studies reported in published literature. Databases from the most general to special cancer-related ones have been included. Most commonly used methods of structure-based analysis of molecules have been reviewed, along with some case studies where they have been used in cancer research. This article is expected to be of use for general bioinformatics researchers interested in cancer and will also provide an update to those who have been actively pursuing this field of research.

  9. Administrative Assistant | Center for Cancer Research

    Science.gov (United States)

    An administrative assistant position is available immediately in the Laboratory of Genome Integrity (LGI) within the Center for Cancer Research (CCR) in the National Cancer Institute (NCI). The LGI is actively looking for someone with administrative skills who will facilitate personnel, travel and related demands that support the laboratory chief, all principal investigators and postdoctoral fellows and laboratory support staff. 

  10. International topical meeting. Research Reactor Fuel Management (RRFM) and meeting of the International Group on Reactor Research (IGORR)

    International Nuclear Information System (INIS)

    2007-01-01

    Nuclear research and test reactors have been in operation for over 60 years, over 270 research reactors are currently operating in more than 50 countries. This meeting is dedicated to different aspects of research reactor fuels: new fuels for new reactors, the conversion to low enriched uranium fuels, spent fuel management and computational tools for core simulation. About 80 contributions are reported in this document, they are organized into 7 sessions: 1) international topics and overview on new projects and fuel, 2) new projects and upgrades, 3) fuel development, 4) optimisation and research reactor utilisation, 5) innovative methods in research reactors physics, 6) safety, operation and research reactor conversion, 7) fuel back-end management, and a poster session. Experience from Australian, Romanian, Libyan, Syrian, Vietnamese, South-African and Ghana research reactors are reported among other things. The Russian program for research reactor spent fuel management is described and the status of the American-driven program for the conversion to low enriched uranium fuels is presented. (A.C.)

  11. Researchers studying alternative to bladder removal for bladder cancer patients | Center for Cancer Research

    Science.gov (United States)

    A new phase I clinical trial conducted by researchers at the Center for Cancer Research (CCR) is evaluating the safety and tolerability, or the degree to which any side effects can be tolerated by patients, of a two-drug combination as a potential alternative to bladder removal for bladder cancer patients. The trial targets patients with non-muscle invasive bladder cancer (NMIBC) whose cancers have stopped responding to traditional therapies. Read more...

  12. 75 FR 20618 - Interagency Coordinating Committee on Oil Pollution Research (ICCOPR); Public Meeting

    Science.gov (United States)

    2010-04-20

    ... Oil Pollution Research (ICCOPR) will hold a public meeting in Seattle, Washington to hear comments on the priorities of oil pollution research, including projects in the Arctic environment. This meeting... SECURITY Coast Guard Interagency Coordinating Committee on Oil Pollution Research (ICCOPR); Public Meeting...

  13. Nebraska Prostate Cancer Research Program

    Science.gov (United States)

    2014-07-01

    2010). Therapeutic Potential of Curcumin : Inhibition of MIC-1/GDF-15 Expression in Prostate Cancer Cells Exposed to Heavy Metal Carcinogen. UNMC...to monitor "What effect do Curcumin , NiCl2, and CoCl2 has on PC3M, LnCap, RWPE1, and PC3 cell lines." She plans on using the knowledge gained during...of Curcumin : Inhibition of MIC-1/GDF-15 Expression in Prostate Cancer Cells Exposed to Heavy Metal Carcinogen Brittany T. Jones, Poomy Pandey

  14. Proceedings of the Strategy Meeting for the Development of an International Consortium for Chinese Medicine and Cancer

    Directory of Open Access Journals (Sweden)

    Jeffrey D. White

    2017-12-01

    Full Text Available On November 3, 2014, in Bethesda, MD, the Office of Cancer Complementary and Alternative Medicine of the National Cancer Institute held a meeting to examine the potential utility and feasibility of establishing an international consortium for Chinese medicine and cancer. There is significant interest in the West in using components of Chinese medicine (CM —such as botanicals and herbal medicines, acupuncture and acupressure, and qigong—in the field of oncology, as potential anticancer agents, for symptom management, and to improve quality of life. The proposal for a consortium on CM came from the Chinese Academy of Chinese Medical Sciences, with the aims of improving scientific communications and collaborations and modernizing the studies of CM for cancer. The US National Cancer Institute’s Office of Cancer Complementary and Alternative Medicine agreed to work with Chinese Academy of Chinese Medical Sciences to explore the feasibility of establishing an international consortium for Chinese medicine and cancer. At the meeting, participants from the United States, China, Canada, Australia, and Korea discussed issues in CM and cancer research, treatment, and management, including potential mechanisms of action, proof of efficacy, adverse effects, regulatory issues, and the need for improving the quality of randomized clinical trials of CM treatments and supportive care interventions. Presented in these proceedings are some of the main issues and opportunities discussed by workshop participants.

  15. DCB - Cancer Immunology, Hematology, and Etiology Research

    Science.gov (United States)

    Part of NCI’s Division of Cancer Biology’s research portfolio, studies supported include the characterization of basic mechanisms relevant to anti-tumor immune responses and hematologic malignancies.

  16. NIH Research Leads to Cervical Cancer Vaccine

    Science.gov (United States)

    ... Transmitted Diseases NIH Research Leads to Cervical Cancer Vaccine Past Issues / Fall 2008 Table of Contents For ... Douglas Lowy (left) and John Schiller developed the vaccine to prevent HPV infection in women, the cause ...

  17. The HPV Vaccine | Center for Cancer Research

    Science.gov (United States)

    Two researchers leveraged CCR’s unique environment of investigator-driven inquiry to pursue studies of two cancer-causing genes that eventually led to the development of a vaccine against two forms of human papillomavirus.

  18. Globus | Informatics Technology for Cancer Research (ITCR)

    Science.gov (United States)

    Globus software services provide secure cancer research data transfer, synchronization, and sharing in distributed environments at large scale. These services can be integrated into applications and research data gateways, leveraging Globus identity management, single sign-on, search, and authorization capabilities. Globus Genomics integrates Globus with the Galaxy genomics workflow engine and Amazon Web Services to enable cancer genomics analysis that can elastically scale compute resources with demand.

  19. Human Research Program 2010 Chair Standing Review Panel Meeting

    Science.gov (United States)

    Steinberg, Susan

    2011-01-01

    The 13 Human Research Program (HRP) Standing Review Panel (SRP) Chairs, and in some cases one or two additional panel members (see section XIV, roster) referred to as the Chair (+1) SRP throughout this document, met at the NASA Johnson Space Center (JSC) on December 7, 2010 to allow the HRP Elements and Projects to report on their progress over the past year, their current status, and their plans for the upcoming year based on NASA's current goals and objectives for human space exploration. A large focus of the meeting was also used to discuss integration across the HRP scientific disciplines based on a recommendation from the 2009 HRP SRP review. During the one-day meeting, each of the HRP Elements and Projects presented the changes they made to the HRP Integrated Research Plan (IRP Rev. B) over the last year, and what their top three areas of integration are between other HRP Elements/Projects. The Chair (+1) SRP spent sufficient time addressing the panel charge, either as a group or in a separate closed session, and the Chair (+1) SRP and the HRP presenters and observers, in most cases, had sufficient time to discuss during and after the presentations. The SRP made a final debriefing to the HRP Program Scientist, Dr. John B. Charles, prior to the close of the meeting on December 7, 2010. Overall, the Chair (+1) SRP concluded that most of the HRP Elements/Projects did a commendable job during the past year in addressing integration across the HRP scientific disciplines with the available resources. The Chair (+1) SRP agreed that the idea of integration between HRP Elements/Projects is noble, but believes all parties involved should have the same definition of integration, in order to be successful. The Chair (+1) SRP also believes that a key to successful integration is communication among the HRP Elements/Projects which may present a challenge. The Chair (+1) SRP recommends that the HRP have a workshop on program integration (with HRP Element

  20. Developmental Scientist | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  1. 77 FR 15783 - National Cancer Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-03-16

    ... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel Nanotechnology... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... proposals. Place: National Institutes of Health, National Cancer Institute, 6116 Executive Blvd., Conference...

  2. Radiation related basic cancer research

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung Hoon; Yoo, Young Do; Hong, Seok Il [and others

    2000-04-01

    We studied the mechanism of radiation-induced apoptosis, the factors involved signaling, and the establishment of radiation-resistant cell lines in this study. During the TGF beta-stimulated epithelial mesenchymal transition(EMT), actin rearrangement occurred first and fibronectin matrix assembly followed. These two events were considered independent since cytochalasin-D did not inhibit TGF stimulated matrix assembly and fibronectin supplementation did not induce EMT. During EMT, alpha 5 beta 1 integrin and alpha v integrin have increased but MMP activation was not accompanied, which suggest that induction of extracellular matrix and activation of integrins may be main contributor for the EMT. Serum depriving induced apoptosis of HUVECs was prevented by vascular endothelial growth factor(VEGF) and PMA. The apoptosis prevention by VEGF and PMA were conformed by DNA fragmentation assay. The p53 expression level was down regulated by VEGF and PMA compared with serum deprived HUVECs. However, VEGF and PMA induces c-Myc expression level on these cells. We made the 5 radiation-resistant clones from breast, lung and cervical cancer cells. More than 70%, 100% and 50% increased resistance was detected in breast cancer cells, lung cancer cells, and cervical cells, respectively. We carried out differential display-PCR to clone the radiation-resistant genes. 9 out of 10 genes were analyzed their sequence.

  3. Radiation related basic cancer research

    International Nuclear Information System (INIS)

    Lee, Seung Hoon; Yoo, Young Do; Hong, Seok Il

    2000-04-01

    We studied the mechanism of radiation-induced apoptosis, the factors involved signaling, and the establishment of radiation-resistant cell lines in this study. During the TGF beta-stimulated epithelial mesenchymal transition(EMT), actin rearrangement occurred first and fibronectin matrix assembly followed. These two events were considered independent since cytochalasin-D did not inhibit TGF stimulated matrix assembly and fibronectin supplementation did not induce EMT. During EMT, alpha 5 beta 1 integrin and alpha v integrin have increased but MMP activation was not accompanied, which suggest that induction of extracellular matrix and activation of integrins may be main contributor for the EMT. Serum depriving induced apoptosis of HUVECs was prevented by vascular endothelial growth factor(VEGF) and PMA. The apoptosis prevention by VEGF and PMA were conformed by DNA fragmentation assay. The p53 expression level was down regulated by VEGF and PMA compared with serum deprived HUVECs. However, VEGF and PMA induces c-Myc expression level on these cells. We made the 5 radiation-resistant clones from breast, lung and cervical cancer cells. More than 70%, 100% and 50% increased resistance was detected in breast cancer cells, lung cancer cells, and cervical cells, respectively. We carried out differential display-PCR to clone the radiation-resistant genes. 9 out of 10 genes were analyzed their sequence

  4. Assessing excellence in translational cancer research: a consensus based framework.

    Science.gov (United States)

    Rajan, Abinaya; Caldas, Carlos; van Luenen, Henri; Saghatchian, Mahasti; van Harten, Wim H

    2013-10-29

    It takes several years on average to translate basic research findings into clinical research and eventually deliver patient benefits. An expert-based excellence assessment can help improve this process by: identifying high performing Comprehensive Cancer Centres; best practices in translational cancer research; improving the quality and efficiency of the translational cancer research process. This can help build networks of excellent Centres by aiding focused partnerships. In this paper we report on a consensus building exercise that was undertaken to construct an excellence assessment framework for translational cancer research in Europe. We used mixed methods to reach consensus: a systematic review of existing translational research models critically appraised for suitability in performance assessment of Cancer Centres; a survey among European stakeholders (researchers, clinicians, patient representatives and managers) to score a list of potential excellence criteria, a focus group with selected representatives of survey participants to review and rescore the excellence criteria; an expert group meeting to refine the list; an open validation round with stakeholders and a critical review of the emerging framework by an independent body: a committee formed by the European Academy of Cancer Sciences. The resulting excellence assessment framework has 18 criteria categorized in 6 themes. Each criterion has a number of questions/sub-criteria. Stakeholders favoured using qualitative excellence criteria to evaluate the translational research "process" rather than quantitative criteria or judging only the outputs. Examples of criteria include checking if the Centre has mechanisms that can be rated as excellent for: involvement of basic researchers and clinicians in translational research (quality of supervision and incentives provided to clinicians to do a PhD in translational research) and well designed clinical trials based on ground-breaking concepts (innovative

  5. Adherence to the World Cancer Research Fund/American Institute for Cancer Research lifestyle recommendations in colorectal cancer survivors

    NARCIS (Netherlands)

    Winkels, Renate M.; Lee, van Linde; Beijer, Sandra; Bours, Martijn J.; Duijnhoven, van Fränzel J.B.; Geelen, Anouk; Hoedjes, Meeke; Mols, Floortje; Vries, de Jeanne; Weijenberg, Matty P.; Kampman, Ellen

    2016-01-01

    We examined adherence to the eight The World Cancer Research Foundation/American Institute for Cancer Research (WCRF/AICR) recommendations on diet, physical activity, and body weight among colorectal cancer survivors, and whether adherence was associated with intention to eat healthy and with the

  6. Cancer systems biology: signal processing for cancer research

    Science.gov (United States)

    Yli-Harja, Olli; Ylipää, Antti; Nykter, Matti; Zhang, Wei

    2011-01-01

    In this editorial we introduce the research paradigms of signal processing in the era of systems biology. Signal processing is a field of science traditionally focused on modeling electronic and communications systems, but recently it has turned to biological applications with astounding results. The essence of signal processing is to describe the natural world by mathematical models and then, based on these models, develop efficient computational tools for solving engineering problems. Here, we underline, with examples, the endless possibilities which arise when the battle-hardened tools of engineering are applied to solve the problems that have tormented cancer researchers. Based on this approach, a new field has emerged, called cancer systems biology. Despite its short history, cancer systems biology has already produced several success stories tackling previously impracticable problems. Perhaps most importantly, it has been accepted as an integral part of the major endeavors of cancer research, such as analyzing the genomic and epigenomic data produced by The Cancer Genome Atlas (TCGA) project. Finally, we show that signal processing and cancer research, two fields that are seemingly distant from each other, have merged into a field that is indeed more than the sum of its parts. PMID:21439242

  7. Prostate Cancer Stem-Like Cells | Center for Cancer Research

    Science.gov (United States)

    Prostate cancer is the third leading cause of cancer-related death among men, killing an estimated 27,000 men each year in the United States. Men with advanced prostate cancer often become resistant to conventional therapies. Many researchers speculate that the emergence of resistance is due to the presence of cancer stem cells, which are believed to be a small subpopulation of tumor cells that can self-renew and give rise to more differentiated tumor cells. It is thought that these stem cells survive initial therapies (such as chemotherapy and hormone therapy) and then generate new tumor cells that are resistant to these standard treatments. If prostate cancer stem cells could be identified and characterized, it might be possible to design treatments that prevent resistance.

  8. 75 FR 10295 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-03-05

    ...; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5.... Place: Legacy Hotel and Meeting Center, 1775 Rockville Pike, Rockville, MD 20852. Contact Person: Gerald... evaluate contract proposals. Place: Legacy Hotel and Meeting Center, 1775 Rockville Pike, Rockville, MD...

  9. 76 FR 14675 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-03-17

    ...; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5.... Place: Hilton Washington DC/Rockville Hotel and Executive Meeting Center, 1750 Rockville Pike, Rockville... Hotel and Executive Meeting Center; 1750 Rockville Pike, Rockville, MD 20852. Contact Person: Peter J...

  10. Five Policy Levers To Meet The Value Challenge In Cancer Care.

    Science.gov (United States)

    Callahan, Ryan; Darzi, Ara

    2015-09-01

    The burden of cancer on public finances is a serious concern for policy makers. More people are developing cancer, and as standards of care have risen, more are surviving and requiring longer-term care. Precision medicine promises better outcomes but demands commensurately higher payments for care. As both incidence and per case costs rise, we suggest that the task of expanding access to high-quality cancer care poses a "value challenge" that policies in many countries are inadequate to meet. Policy makers should respond with a new approach. We explore questions that policy makers will need to consider regarding objectives, barriers, and levers for policy development. We use transparency and accountability as cornerstones of a new approach to promote value-based decision making. Although barriers to advancing this agenda are formidable, we recommend that governments define common standards for value-based accounting; serve as information brokers for evidence development; pioneer value-based procurement of goods and services; engage in deliberative democracy in cancer care; and educate communities to facilitate knowledge sharing between communities of patients, their caretakers, and researchers. Project HOPE—The People-to-People Health Foundation, Inc.

  11. Report on the Workshop and Regular Meeting of the Imode-CKD and Bcmolmed Marie Curie Training and Research Programs.

    Science.gov (United States)

    Krochmal, Magdalena; Cisek, Katryna; Markoska, Katerina; Spasovski, Goce; Vlahou, Antonia

    2015-01-01

    A Workshop and Regular Meeting of the Marie Curie Training and Research Programs iMODECKD (Identification of the Molecular Determinants of established Chronic Kidney Disease) and BCMolMed (Molecular Medicine for Bladder Cancer) was held from 20-22 March at the Macedonian Academy of Science and Arts (MASA). The meeting was hosted by the participating center University of Skopje (SKO) - Goce Spasovski and MASA - Momir Polenakovic (R. Macedonia). The representative from MASA proteomic research center - Katerina Davalieva (R. Macedonia) had presentation on proteomic research in prostate cancer (PCa). 40 researchers from 13 different countries participated at the meeting. The Workshop was devoted on "Chronic Kidney Disease: Clinical Management issues", and consisted of 15 oral presentations given by nephrologists and experts in the field of CKD. Raymond Vanholder (Belgium) - past president of ERA-EDTA had a keynote lecture on "CKD: Questions that need to be answered and are not (or at least not entirely)". The workshop continued in four sessions with lectures from Alberto Ortiz (Spain), Olivera Stojceva-Taneva (R. Macedonia), Dimitrios Goumenos (Greece), Joachim Beige (Germany), Marian Klinger (Poland), Goce Spasovski (R. Macedonia), Joachim Jankowski (Germany), Adalbert Schiller (Romania), Robert Johnson (USA), Franco Ferrario (Italy), Ivan Rychlik (Czech Republic), Fulvio Magni (Italy) and Giovambattista Capasso (Italy), all covering a training theme. Within the meeting there were two lectures on complimentary skills for ethics in science and career advancement from two principal investigators - Goce Spasovski (R. Macedonia) and Joost Schanstra (France). During the Regular Meeting, 13 PhD students i.e. Early Stage Researchers and one Experienced Researcher from both Programs presented their work and progress within iMODE-CKD and BCMolMed projects. This meeting was a great opportunity to exchange experience and ideas in the field of systems biology approaches and

  12. 78 FR 47715 - National Human Genome Research Institute; Notice of Meeting

    Science.gov (United States)

    2013-08-06

    ... HUMAN SERVICES National Institutes of Health National Human Genome Research Institute; Notice of Meeting... hereby given of a meeting of the National Advisory Council for Human Genome Research. The meeting will be... unwarranted invasion of personal privacy. Name of Committee: National Advisory Council for Human Genome...

  13. Reconstruction of the pedagogical-research matrix: meeting our paradigms

    Directory of Open Access Journals (Sweden)

    Paula Pereira Scherre

    2016-09-01

    Full Text Available This abstract has its origins in the call of some authors who indicated the need for developing an Education, teacher-training, and scientific knowledge production, based upon the Complexity and Transdisciplinarity. My goal is to reflect on a (transformative path of reconstruction of the pedagogical-research matrix, developing awareness of the subjacent pragmatic roots of the professional being and doing, as well as teachers and researchers. This meeting was possible through the formative methodology and the research called ‘Autoformative Narrative’ resulting from a qualitative study which has been systematized and theorized throughout my PhD in Education. As a result, we have the present matrix identification, in its pedagogical and research dimensions, the recognition of its foundations in a Cartesian Newtonian paradigm and the openness to the building of another emerging matrix under the Complexity Paradigm, and the Emerging Educational Paradigm. Even knowing that the different paradigms will keep co-existing within me, being aware of how they influence me allows me to improve my professional being and doing. I believe this (Autoformative process enables us to take control of the different formation types and contexts, to empower ourselves with our history and life project, to attribute sense to what is experienced and learned, to value knowledge, learning processes and experiences, in a continued dialogue with disciplinary and theoretical knowledge. I aim to contribute so that learning environments (in class, virtual, and hybrid can be places and times of (transformation, self-knowledge, research, authorship, meaning, creativity, self-knowledge production, and scientific knowledge.

  14. TCGA researchers identify 4 subtypes of stomach cancer

    Science.gov (United States)

    Stomach cancers fall into four distinct molecular subtypes, researchers with The Cancer Genome Atlas (TCGA) Network have found. Scientists report that this discovery could change how researchers think about developing treatments for stomach cancer, also c

  15. Antiproton radiation found effective in cancer research

    CERN Multimedia

    2003-01-01

    "An international collaboration of scientists has completed the first ever antiproton beam experiments designed to reveal the biological effectiveness of antiproton radiation in terminating cells used for cancer research...PBar Labs assembled the collaboration at CERN (European Organization for Nuclear Research in Geneva) to perform the measurements" (1 page).

  16. FAA and NASA UTM Research Transition Team: Communications and Navigation (CN) Working Group (WCG) Kickoff Meeting

    Science.gov (United States)

    Jung, Jaewoo; Larrow, Jarrett

    2017-01-01

    This is NASA FAA UTM Research Transition Team Communications and Navigation working group kick off meeting presentation that addresses the followings. Objectives overview Overall timeline and scope Outcomes and expectations Communication method and frequency of meetings Upcoming evaluation Next steps.

  17. Ovarian Cancer: Prevention, Detection and Treatment of the Disease and Its Recurrence. Molecular Mechanisms and Personalized Medicine Meeting Report

    Science.gov (United States)

    Modugno, Francesmary; Edwards, Robert P.

    2012-01-01

    Objective To review the current understanding of the underlying molecular, biologic and genetic mechanisms involved in ovarian cancer development and how these mechanisms can be targets for prevention, detection and treatment of the disease and its recurrence. Methods In May 2012, we convened a meeting of researchers, clinicians and consumer advocates to review the state of current knowledge on molecular mechanisms and identify fruitful areas for further investigations. Results The meeting consisted of seven scientific sessions, ranging from Epidemiology, Early Detection, and Biology to Therapeutics and Quality of Life. Sessions consisted of talks and panel discussions by international leaders in ovarian cancer research. A special career-development session by the CDMRP Department of Defense Ovarian Cancer Academy as well as an oral abstract and poster session showcased promising new research by junior scientists. Conclusions Technological advances in the last decade have increased our knowledge of the molecular mechanisms involved in a host of biological activities related to ovarian cancer. Understanding the role these mechanisms play in cancer initiation and progression will help lead to the development of prevention and treatment modalities that can be personalized to each patient, thereby helping to overcome this highly-fatal malignancy. PMID:23013733

  18. In Absentia: An Exploratory Study of How Patients Are Considered in Multidisciplinary Cancer Team Meetings

    NARCIS (Netherlands)

    Hahlweg, P.; Hoffmann, J.; Harter, M.; Frosch, D.L.; Elwyn, G.; Scholl, I.

    2015-01-01

    BACKGROUND: Multidisciplinary team meetings and shared decision-making are potential means of delivering patient-centred care. Not much is known about how those two paradigms fit together in cancer care. This study aimed to investigate how decisions are made in multidisciplinary team meetings and

  19. 77 FR 6826 - Advisory Committee for Environmental Research and Education; Notice of Meeting

    Science.gov (United States)

    2012-02-09

    ... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... environmental research and education. Agenda: Wednesday, March 14, 2012 Update on NSF environmental research and... Science Foundation announces the following meeting: Name: Advisory Committee for Environmental Research...

  20. 77 FR 9731 - Rehabilitation Research and Development Service Scientific Merit Review Board; Notice of Meeting

    Science.gov (United States)

    2012-02-17

    ... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Service Scientific Merit..., Rehabilitation Research and Development Service, and the Chief Research and Development Officer on the scientific...-463 (Federal Advisory Committee Act) that a meeting of the Rehabilitation Research and Development...

  1. IGORR 7: Proceedings of the 7. meeting of the International Group On Research Reactors

    International Nuclear Information System (INIS)

    1999-01-01

    According to the subjects covered the papers presented at the meeting were divided into following sessions: New research reactor projects; secondary neutron sources; New research reactor facilities; Improvement of Research Reactors Facilities; Research and Development Needs

  2. Research on Immunotherapy: Using the Immune System to Treat Cancer

    Science.gov (United States)

    ... Home Research Key Initiatives Immunotherapy NCI’s Role in Immunotherapy Research An oral squamous cancer cell (white) being ... immunotherapy to more patients with cancer. NCI-Supported Immunotherapy Research Immunotherapy research funded by or conducted at ...

  3. Multidisciplinary Intervention of Early, Lethal Metastatic Prostate Cancer: Report From the 2015 Coffey-Holden Prostate Cancer Academy Meeting

    Science.gov (United States)

    Miyahira, Andrea K.; Lang, Joshua M.; Den, Robert B.; Garraway, Isla P.; Lotan, Tamara L.; Ross, Ashley E.; Stoyanova, Tanya; Cho, Steve Y.; Simons, Jonathan W.; Pienta, Kenneth J.; Soule, Howard R.

    2018-01-01

    BACKGROUND The 2015 Coffey-Holden Prostate Cancer Academy Meeting, themed: “Multidisciplinary Intervention of Early, Lethal Metastatic Prostate Cancer,” was held in La Jolla, California from June 25 to 28, 2015. METHODS The Prostate Cancer Foundation (PCF) sponsors an annual, invitation-only, action-tank-structured meeting on a critical topic concerning lethal prostate cancer. The 2015 meeting was attended by 71 basic, translational, and clinical investigators who discussed the current state of the field, major unmet needs, and ideas for addressing earlier diagnosis and treatment of men with lethal prostate cancer for the purpose of extending lives and making progress toward a cure. RESULTS The questions addressed at the meeting included: cellular and molecular mechanisms of tumorigenesis, evaluating, and targeting the microenvironment in the primary tumor, advancing biomarkers for clinical integration, new molecular imaging technologies, clinical trials, and clinical trial design in localized high-risk and oligometastatic settings, targeting the primary tumor in advanced disease, and instituting multi-modal care of high risk and oligometastatic patients. DISCUSSION This article highlights the current status, greatest unmet needs, and anticipated field changes that were discussed at the meeting toward the goal of optimizing earlier interventions to potentiate cures in high-risk and oligometastatic prostate cancer patients. PMID:26477609

  4. Prostate Cancer Research Training Program

    Science.gov (United States)

    2012-05-01

    brief description of research in the la boratories of each University of Iowa mentor. At this point in time the program is 8 weeks long...www.uihealthcare.com/depts/med/urology/urolo gymds/luo.html A major research project in our la boratory is to develop a novel therapeutic...wright.shtml?menu =1&tab=facultyTab The Wright Labo ratory is focuse d on defining the composition, activity, and overall cellul ar function of

  5. Rethinking cancer: current challenges and opportunities in cancer research

    Science.gov (United States)

    Cagan, Ross; Meyer, Pablo

    2017-01-01

    ABSTRACT Cancer therapeutics currently have the lowest clinical trial success rate of all major diseases. Partly as a result of the paucity of successful anti-cancer drugs, cancer will soon be the leading cause of mortality in developed countries. As a disease embedded in the fundamentals of our biology, cancer presents difficult challenges that would benefit from uniting experts from a broad cross-section of related and unrelated fields. Combining extant approaches with novel ones could help in tackling this challenging health problem, enabling the development of therapeutics to stop disease progression and prolong patient lives. This goal provided the inspiration for a recent workshop titled ‘Rethinking Cancer’, which brought together a group of cancer scientists who work in the academic and pharmaceutical sectors of Europe, America and Asia. In this Editorial, we discuss the main themes emerging from the workshop, with the aim of providing a snapshot of key challenges faced by the cancer research community today. We also outline potential strategies for addressing some of these challenges, from understanding the basic evolution of cancer and improving its early detection to streamlining the thorny process of moving promising drug targets into clinical trials. PMID:28381596

  6. Postdoctoral Fellows | Center for Cancer Research

    Science.gov (United States)

    The Oncogenomics section of the Genetics Branch is a multidisciplinary and interdisciplinary translational research programmatic effort with the goal of utilizing genomics to develop novel immunotherapies for cancer. Our group is applying high throughput applied genomics methods including single cell RNAseq, single cell TCR sequencing, DNA sequencing, CRISPR/Cas9, bioinformatics combined with T cell based therapeutics to identify and develop novel immunotherapeutics for human cancer. We work with other investigators within the intramural program as well as industrial and pharmaceutical partners to rapidly translate our findings to the clinic. The program takes advantage of the uniqueness of the National Cancer Institute, (NCI), Center for Cancer Research (CCR) intramural program in that it spans high-risk basic discovery research in immunology, genomics and tumor biology, through preclinical translational research, to paradigm-shifting clinical trials. The position is available immediately. The appointment duration is up to 5 years. Stipends are commensurate with education and experience. Additional information can be found on Dr. Khan’s profile page: https://ccr.cancer.gov/Genetics-Branch/javed-khan

  7. Automation of Technology for Cancer Research.

    Science.gov (United States)

    van der Ent, Wietske; Veneman, Wouter J; Groenewoud, Arwin; Chen, Lanpeng; Tulotta, Claudia; Hogendoorn, Pancras C W; Spaink, Herman P; Snaar-Jagalska, B Ewa

    2016-01-01

    Zebrafish embryos can be obtained for research purposes in large numbers at low cost and embryos develop externally in limited space, making them highly suitable for high-throughput cancer studies and drug screens. Non-invasive live imaging of various processes within the larvae is possible due to their transparency during development, and a multitude of available fluorescent transgenic reporter lines.To perform high-throughput studies, handling large amounts of embryos and larvae is required. With such high number of individuals, even minute tasks may become time-consuming and arduous. In this chapter, an overview is given of the developments in the automation of various steps of large scale zebrafish cancer research for discovering important cancer pathways and drugs for the treatment of human disease. The focus lies on various tools developed for cancer cell implantation, embryo handling and sorting, microfluidic systems for imaging and drug treatment, and image acquisition and analysis. Examples will be given of employment of these technologies within the fields of toxicology research and cancer research.

  8. Summer Prostate Cancer Research Training Program

    Science.gov (United States)

    2017-09-01

    the research program by each mentor will certainly produce important research findings, aided in part by the summer research of the ...adenovirus vaccine in men with prostate cancer. Important in these trials is the safety of the vaccine and its ability to induce anti-tumor immunity... Living in Iowa City for the Summer Housing and Meals - All students will be housed in the Mayflower Residence Hall on the Campus of the University

  9. 76 FR 9353 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute.... Place: Bethesda North Marriott Hotel & Conference Center, 5701 Marinelli Road, Bethesda, MD 20852... Branch, Division of Extramural Activities, National Cancer Institute, 6116 Executive Blvd., Room 8101...

  10. The 2016 Assisi Think Tank Meeting on breast cancer: white paper

    DEFF Research Database (Denmark)

    Aristei, Cynthia; Kaidar-Person, Orit; Arenas, Meritxell

    2016-01-01

    PURPOSE: To identify weak points in daily routine use of radiation therapy (RT) for non-metastatic breast cancer patients, particularly when data are lacking or equivocal, a "think tank" of experts met in Assisi. METHODS: Before the meeting, controversial issues on non-metastatic breast cancer were...

  11. About the Breast and Gynecologic Cancer Research Group | Division of Cancer Prevention

    Science.gov (United States)

    The Breast and Gynecologic Cancer Research Group conducts and fosters the development of research on the prevention and early detection of breast cancer, cervix and human papillomavirus (HPV)-related cancers, endometrial cancers, ovarian cancers, and precursor conditions related to these cancers. |

  12. 78 FR 46357 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2013-07-31

    ... Cancer Institute Board of Scientific Advisors ad hoc Subcommittee on HIV/AIDS Malignancy, August 08, 2013, 10:30 a.m. to 12:00 p.m., National Cancer Institute, NIH, Building 10, Room 10S255, 10 Center Drive... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute...

  13. 78 FR 30933 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-23

    .... Time: 1:00 p.m. to 4:00 p.m. Agenda: To review and evaluate contract proposals. Place: National Cancer... Conference Call). Contact Person: Clifford W Schweinfest, Ph.D., Scientific Review Officer, Special Review... Committee: National Cancer Institute Special Emphasis Panel; Nanotech-Biosensor Platforms for Cancer. Date...

  14. 75 FR 7489 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-02-19

    ... Institute Special Emphasis Panel; NCI Cancer Nanotechnology Training (R25) and Career Development Award (K99... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel; The Early Detection...

  15. 78 FR 16272 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-03-14

    ...: National Cancer Institute Special Emphasis Panel, Nanotechnology RNA Therapeutics. Date: April 18-19, 2013... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel, NCI Provocative Questions. Date: March 28, 2013. Time: 7:30 a.m...

  16. 75 FR 44274 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-07-28

    ... Cancer Institute Special Emphasis Panel, Nanotechnology Imaging and Sensing Platforms for Improved Diagnosis of Cancer. Date: August 31, 2010. Time: 12 p.m. to 1:30 p.m. Agenda: To review and evaluate... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute...

  17. 76 FR 69744 - National Cancer Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-11-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel, Cancer Diagnostic and Therapeutic Agents Enabled by Nanotechnology. Date: November 29, 2011. Time: 8 a.m. to 7 p.m...

  18. 75 FR 26968 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-13

    ...: National Cancer Institute Special Emphasis Panel; Nanotechnology Imaging and Sensing Platforms. Date: June... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel; Adult Brain Tumor Consortium. Date: May 20, 2010. Time: 1 p.m...

  19. Lower Breast Cancer Risk among Women following the World Cancer Research Fund and American Institute for Cancer Research Lifestyle Recommendations: EpiGEICAM Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Adela Castelló

    Full Text Available According to the "World Cancer Research Fund" and the "American Institute of Cancer Research" (WCRF/AICR one in four cancer cases could be prevented through a healthy diet, weight control and physical activity.To explore the association between the WCRF/AICR recommendations and risk of breast cancer.During the period 2006 to 2011 we recruited 973 incident cases of breast cancer and 973 controls from 17 Spanish Regions. We constructed a score based on 9 of the WCRF/AICR recommendations for cancer prevention:: 1Maintain adequate body weight; 2Be physically active; 3Limit the intake of high density foods; 4Eat mostly plant foods; 5Limit the intake of animal foods; 6Limit alcohol intake; 7Limit salt and salt preserved food intake; 8Meet nutritional needs through diet; S1Breastfeed infants exclusively up to 6 months. We explored its association with BC by menopausal status and by intrinsic tumor subtypes (ER+/PR+ & HER2-; HER2+; ER&PR-&HER2- using conditional and multinomial logistic models respectively.Our results point to a linear association between the degree of noncompliance and breast cancer risk. Taking women who met 6 or more recommendations as reference, those meeting less than 3 showed a three-fold excess risk (OR=2.98(CI95%:1.59-5.59, especially for postmenopausal women (OR=3.60(CI95%:1.24;10.47 and ER+/PR+&HER2- (OR=3.60(CI95%:1.84;7.05 and HER2+ (OR=4.23(CI95%:1.66;10.78 tumors. Noncompliance of recommendations regarding the consumption of foods and drinks that promote weight gain in premenopausal women (OR=2.24(CI95%:1.18;4.28; p for interaction=0.014 and triple negative tumors (OR=2.93(CI95%:1.12-7.63; the intake of plant foods in postmenopausal women (OR=2.35(CI95%:1.24;4.44 and triple negative tumors (OR=3.48(CI95%:1.46-8.31; and the alcohol consumption in ER+/PR+&HER2- tumors (OR=1.52 (CI95%:1.06-2.19 showed the strongest associations.Breast cancer prevention might be possible by following the "World Cancer Research Fund" and the

  20. Prostate Cancer Research Trial Helps John Spencer Treat His Cancer | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Prostate Cancer Prostate Cancer Research Trial Helps John Spencer Treat His Cancer ... because of timely detection and treatment of his prostate cancer. He participated in an NIH-sponsored clinical trial. ...

  1. 76 FR 3642 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-20

    ...; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5... evaluate grant applications. Place: Legacy Hotel and Meeting Center, 1775 Rockville Pike, Rockville, MD... North Marriott Hotel & Conference Center, 5701 Marinelli Road, Bethesda, MD 20852. Contact Person...

  2. 78 FR 64223 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-28

    ..., November 07, 2013, 8:00 a.m. to November 07, 2013, 6:00 p.m., Bethesda North Marriott Hotel & Conference..., 2013, 78FR53154. The meeting notice is amended to change the meeting location to the Gaithersburg...

  3. Cancer multidisciplinary team meetings in practice: Results from a multi-institutional quantitative survey and implications for policy change.

    Science.gov (United States)

    Rankin, Nicole M; Lai, Michelle; Miller, Danielle; Beale, Philip; Spigelman, Allan; Prest, Gabrielle; Turley, Kim; Simes, John

    2018-02-01

    Multidisciplinary care is advocated as best practice in cancer care. Relatively little is documented about multidisciplinary team (MDT) meeting functioning, decision making and the use of evidence to support decision making in Australia. This descriptive study aimed to examine team functioning, the role of team meetings and evidence use in MDTs whose institutions are members of Sydney Catalyst Translational Cancer Research Centre. We designed a structured 40-item survey instrument about topics that included meeting purpose, organization, resources and documentation; caseload estimates; use of evidence and quality assurance; patient involvement and supportive care needs; and open-ended items about the MDTs strengths and weaknesses. Participants were invited to participate via email and the survey was administered online. Data were analyzed using descriptive and comparative statistics. Thirty-seven MDTs from seven hospitals participated (100% response) and represented common (70%) and rare tumor groups (30%). MDT meeting purpose was reported as treatment (100%) or diagnostic decision making (88%), or for education purposes (70%). Most MDTs based treatment decisions on group consensus (92%), adherence to clinical practice guidelines (57%) or other evidence-based medicine sources (33%). The majority of MDTs discussed only a proportion of new patients at each meeting emphasizing the importance of educational aspects for other cases. Barriers exist in the availability of data to enable audit and reflection on evidence-based practice. MDT strengths included collaboration and quality discussion about patients. MDT meetings focus on treatment decision making, with group consensus playing a significant role in translating research evidence from guidelines into clinical decision making. With a varying proportion of patients discussed in each MDT meeting, a wider audit of multidisciplinary care would enable more accurate assessments of whether treatment recommendations are in

  4. Breast Cancer Research Training Grant

    Science.gov (United States)

    1997-10-01

    Pharmacology and Experimental Therapeutics Program in Research on Women-s Health Female Reproductive Aging : A Window into the Aging Brain Phyllis M. Wise...of luteinizing hormone-releasing hormone neuronal function. - PLEASE POST Phone: 638-4500 Department of B0Si PATHOLOGYI and Laboratory Medicine Boston...AT 1:00 SEPTEMBER 26 Jacob Sloane Brain inflammation in pathologic aging . Department of Pathology & Laboratory Medicine OCTOBER 3 Dr. Sun Tam The

  5. Flow Cytometry Scientist | Center for Cancer Research

    Science.gov (United States)

    The Basic Science Program (BSP) pursues independent, multidisciplinary research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics. Research efforts and support are an integral part of the Center for Cancer Research (CCR) at the Frederick National Laboratory for Cancer Research (FNLCR). KEY ROLES/RESPONSIBILITIES The Flow Cytometry Core (Flow Core) in the Cancer and Inflammation Program (CIP) is a service core which supports the research efforts of the CCR by providing expertise in the field of flow cytometry (fluorescence cell sorting) with the goal of gaining a more thorough understanding of the biology of the immune system, cancer, and inflammation processes. The Flow Core provides service to 12-15 CIP laboratories and more than 22 non-CIP laboratories. Flow core staff provide technical advice on the experimental design of applications, which include immunological phenotyping, cell function assays, and cell cycle analysis. Work is performed per customer requirements, and no independent research is involved. Flow Cytometry Scientist - The individual will be responsible for: Daily management of the Flow Cytometry Core, to include the supervision and guidance of technical staff members Monitor performance of and maintain high-dimensional flow cytometer analyzers and cell sorters Operate high-dimensional flow cytometer analyzers and cell sorters Provide scientific expertise to the user community and facilitate the development of cutting-edge technologies Interact with Flow Core users and customers, and provide technical and scientific advice, and guidance regarding their experiments, including possible collaborations Train staff and scientific end users on the use of flow cytometry in their research, as well as teach them how to operate and troubleshoot the bench-top analyzer instruments Prepare and deliver lectures, as well as one-on-one training sessions, with customers/users Ensure that protocols are up

  6. On the path to translation: Highlights from the 2010 Canadian Conference on Ovarian Cancer Research

    Directory of Open Access Journals (Sweden)

    Thériault Brigitte L

    2011-06-01

    Full Text Available Abstract Ovarian cancer continues to be the most lethal of the gynaecologic malignancies due to the lack of early detection, screening strategies and ineffective therapeutics for late-stage metastatic disease, particularly in the recurrent setting. The gathering of researchers investigating fundamental pathobiology of ovarian cancer and the clinicians who treat patients with this insidious disease is paramount to meeting the challenges we face. Since 2002, the Canadian Conference on Ovarian Cancer Research, held every two years, has served this essential purpose. The objectives of this conference have been to disseminate new information arising from the most recent ovarian cancer research and identify the most pressing challenges we still face as scientists and clinicians. This is best accomplished through direct encounters and exchanges of innovative ideas among colleagues and trainees from the realms of basic science and clinical disciplines. This meeting has and continues to successfully facilitate rapid networking and establish new collaborations from across Canada. This year, more guest speakers and participants from other countries have extended the breadth of the research on ovarian cancer that was discussed at the meeting. This report summarizes the key findings presented at the fifth biennial Canadian Conference on Ovarian Cancer Research held in Toronto, Ontario, and includes the important issues and challenges we still face in the years ahead to make a significant impact on this devastating disease.

  7. Space facilities: Meeting future needs for research, development, and operations

    Science.gov (United States)

    1994-01-01

    The National Facilities Study (NFS) represents an interagency effort to develop a comprehensive and integrated long-term plan for world-class aeronautical and space facilities that meet current and projected needs for commercial and government aerospace research and development and space operations. At the request of NASA and the DOD, the National Research Council's Committee on Space Facilities has reviewed the space related findings of the NFS. The inventory of more than 2800 facilities will be an important resource, especially if it continues to be updated and maintained as the NFS report recommends. The data in the inventory provide the basis for a much better understanding of the resources available in the national facilities infrastructure, as well as extensive information on which to base rational decisions about current and future facilities needs. The working groups have used the inventory data and other information to make a set of recommendations that include estimates of cast savings and steps for implementation. While it is natural that the NFS focused on cost reduction and consolidations, such a study is most useful to future planning if it gives equal weight to guiding the direction of future facilities needed to satisfy legitimate national aspirations. Even in the context of cost reduction through facilities closures and consolidations, the study is timid about recognizing and proposing program changes and realignments of roles and missions to capture what could be significant savings and increased effectiveness. The recommendations of the Committee on Space Facilities are driven by the clear need to be more realistic and precise both in recognizing current incentives and disincentives in the aerospace industry and in forecasting future conditions for U.S. space activities.

  8. Participants in a medical applications meeting hosted by CERN Head of Medical Applications S. Myers with J. E. Celis, Chairman of the Policy Committee, European Cancer Organisation, President, European Association for Cancer Research and Prof. JM. Gago, President of Laboratório de Instrumentação e Física Experimental de Partículas (LIP) and Former Minister for Science, Technology and Higher Education of Portugal of the XVII Governo. Were also participating: CERN Life Science Adviser M. Dosanjh with U. Ringborg R. Lewensohn, A. Brahme, R. Moeckli, O. Jäkel and S. Pieck.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    Participants in a medical applications meeting hosted by CERN Head of Medical Applications S. Myers with J. E. Celis, Chairman of the Policy Committee, European Cancer Organisation, President, European Association for Cancer Research and Prof. JM. Gago, President of Laboratório de Instrumentação e Física Experimental de Partículas (LIP) and Former Minister for Science, Technology and Higher Education of Portugal of the XVII Governo. Were also participating: CERN Life Science Adviser M. Dosanjh with U. Ringborg R. Lewensohn, A. Brahme, R. Moeckli, O. Jäkel and S. Pieck.

  9. 75 FR 51275 - National Institute of Dental and Craniofacial Research; Notice of Meeting

    Science.gov (United States)

    2010-08-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Dental... Dental and Craniofacial Research Council. The meeting will be open to the public as indicated below, with... listed below in advance of the meeting. The meeting will be closed to the public in accordance with the...

  10. 75 FR 82033 - National Institute of Dental and Craniofacial Research; Notice of Meeting

    Science.gov (United States)

    2010-12-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Dental... Dental and Craniofacial Research Council. The meeting will be open to the public as indicated below, with... listed below in advance of the meeting. The meeting will be closed to the public in accordance with the...

  11. First research co-ordination meeting of the co-ordinated research programme on development of kits for radioimmunometric assays for tumour markers. Summary report

    International Nuclear Information System (INIS)

    1997-01-01

    Cancer is one of the major reasons for mortality and a great deal of research goes on in many areas related to cancer all through the world. The concept of 'tumor markers' has greatly aided the management of cancer, especially for follow up of the treated patients. Immunoassays that are used for measurement of sub-picomolar quantities of biomolecules such as hormones have been developed for the measurement of tumor markers too and these are widely used for monitoring the patients. The current co-ordinated research program on 'Development of Immunometric Assays for the Tumor Makers: PSA, free PSA and TPS' was born out of the advise from a group of specialists from the field oncology and nuclear medicine who met to discuss initially (Advisory Group Meeting, Colombo, August 1996) to identify the most appropriate markers and later (Consultants' Meeting, Glasgow, 21-25 April 1997) to identify the details of the procedure to follow. The first Research Co-ordination Meeting of this group was held in Vienna from 9-12 December 1997 to review the plans of each participant and the steps to be taken to realize the goal of this CRP. The meeting was attended by participants from the ten laboratories. The meeting discussed all salient aspects of the IRMA development for PSA and TPS. The modalities of working out the plans were thoroughly considered and the key inputs for the program to take off were identified. In conclusion, all the nine contract holding participants would develop the IRMAs for PSA (free and total) and TPS (Uruguay)

  12. Science at Sea: Meeting Future Oceanographic Goals with a Robust Academic Research Fleet

    OpenAIRE

    Fleet, COEOTNOR; Board, OS; Studies, DOEAL; Council, NR

    2009-01-01

    Meeting Future Oceanographic Goals with a Robust Academic Research Fleet Committee on Evolution of the National Oceanographic Research Fleet, Ocean Studies Board, Division on Earth and Life Studies, National Research Council ...

  13. 76 FR 7881 - Advisory Committee for Environmental Research and Education; Notice of Meeting

    Science.gov (United States)

    2011-02-11

    ... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... support for environmental research and education. Agenda March 16 Update on recent NSF environmental... Science Foundation announces the following meeting: Name: Advisory Committee for Environmental Research...

  14. 75 FR 50009 - Advisory Committee for Environmental Research and Education; Notice of Meeting

    Science.gov (United States)

    2010-08-16

    ... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... support for environmental research and education. Agenda September 8, 2010 Update on recent NSF... Science Foundation announces the following meeting: Name: Advisory Committee for Environmental Research...

  15. 76 FR 47611 - Advisory Committee for Environmental Research And Education; Notice of Meeting

    Science.gov (United States)

    2011-08-05

    ... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research And Education; Notice of... support for environmental research and education. Agenda September 8, 2011 Update on NSF environmental... Science Foundation announces the following meeting: Name: Advisory Committee for Environmental Research...

  16. 78 FR 48200 - Advisory Committee for Environmental Research and Education; Notice of Meeting

    Science.gov (United States)

    2013-08-07

    ... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... research and education. Agenda September 11, 2013 Update on NSF environmental research and education... National Science Foundation announces the following meeting: Name: Advisory Committee for Environmental...

  17. 77 FR 796 - Meeting of the Advisory Council on Alzheimer's Research, Care, and Services

    Science.gov (United States)

    2012-01-06

    ... HUMAN SERVICES Meeting of the Advisory Council on Alzheimer's Research, Care, and Services AGENCY... announces public meeting of the Advisory Council on Alzheimer's Research, Care, and Services (Advisory..., section 10(a)(1) and (a)(2)). The Advisory Council on Alzheimer's Research, Care, and Services will...

  18. 77 FR 38291 - Meeting of the Advisory Council on Alzheimer's Research, Care, and Services

    Science.gov (United States)

    2012-06-27

    ... HUMAN SERVICES Meeting of the Advisory Council on Alzheimer's Research, Care, and Services AGENCY...: This notice announces the public meeting of the Advisory Council on Alzheimer's Research, Care, and... U.S.C. App. 2, section 10(a)(1) and (a)(2)). The Advisory Council on Alzheimer's Research, Care, and...

  19. 77 FR 58557 - Meeting of the Advisory Council on Alzheimer's Research, Care, and Services

    Science.gov (United States)

    2012-09-21

    ... HUMAN SERVICES Meeting of the Advisory Council on Alzheimer's Research, Care, and Services AGENCY... announces the public meeting of the Advisory Council on Alzheimer's Research, Care, and Services (Advisory..., section 10(a)(1) and (a)(2)). The Advisory Council on Alzheimer's Research, Care, and Services provides...

  20. 78 FR 38346 - Advisory Council on Alzheimer's Research, Care, and Services; Meeting

    Science.gov (United States)

    2013-06-26

    ... HUMAN SERVICES Advisory Council on Alzheimer's Research, Care, and Services; Meeting AGENCY: Assistant... public meeting of the Advisory Council on Alzheimer's Research, Care, and Services (Advisory Council). The Advisory Council on Alzheimer's Research, Care, and Services provides advice on how to prevent or...

  1. 78 FR 20318 - Advisory Council on Alzheimer's Research, Care, and Services; Meeting

    Science.gov (United States)

    2013-04-04

    ... HUMAN SERVICES Advisory Council on Alzheimer's Research, Care, and Services; Meeting AGENCY: Assistant... public meeting of the Advisory Council on Alzheimer's Research, Care, and Services (Advisory Council). The Advisory Council on Alzheimer's Research, Care, and Services provides advice on how to prevent or...

  2. 75 FR 32486 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2010-06-08

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee... Review, National Institute of Nursing Research, National Institutes of Health, 6701 Democracy Blvd (DEM 1... Institute of Nursing Research Special Emphasis Panel; NINR End of Life RFA Review Meeting. Date: July 15...

  3. 76 FR 62755 - National Agricultural Research, Extension, Education, and Economics Advisory Board Meeting Notice

    Science.gov (United States)

    2011-10-11

    ..., Education, and Economics Advisory Board Meeting Notice AGENCY: Research, Education, and Economics, United... Research, Extension, Education, and Economics Advisory Board. DATES: The National Agricultural Research, Extension, Education, and Economics Advisory Board will meet November 7-9, 2011. The public may file written...

  4. Summary of Prioritized Research Opportunities. Building America Planning Meeting, November 2-4, 2010

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-02-01

    This report outlines the results of brainstorming sessions conducted at the Building America Fall 2010 planning meeting, in which research teams and national laboratories identified key research priorities to incorporate into multi-year planning, team research agendas, expert meetings, and technical standing committees.

  5. Impact of proteomics on bladder cancer research

    DEFF Research Database (Denmark)

    Celis, Julio E; Gromova, Irina; Moreira, José Manuel Alfonso

    2004-01-01

    Detecting bladder cancer at an early stage and predicting how a tumor will behave and act in response to therapy, as well as the identification of new targets for therapeutic intervention, are among the main areas of research that will benefit from the current explosion in the number of powerful...

  6. 75 FR 25208 - Announcement of Body Armor Research Needs Meeting

    Science.gov (United States)

    2010-05-07

    ... be admitted. Anyone wishing to attend this meeting must register by C.O.B June 4, 2010 in order to..., passport issuing country, passport number, city of birth, country of birth, date of birth, gender, title...

  7. New targets for immunotherapy-based treatment of HPV-related cancers | Center for Cancer Research

    Science.gov (United States)

    Scientists at the Center for Cancer Research and three other cancer research institutions show that immunotherapy treatments that resulted in complete regression of metastatic cervical cancer largely targeted two non-viral antigens. Read more…  

  8. Testicular Cancer Survivorship: Research Strategies and Recommendations

    Science.gov (United States)

    Beard, Clair; Allan, James M.; Dahl, Alv A.; Feldman, Darren R.; Oldenburg, Jan; Daugaard, Gedske; Kelly, Jennifer L.; Dolan, M. Eileen; Hannigan, Robyn; Constine, Louis S.; Oeffinger, Kevin C.; Okunieff, Paul; Armstrong, Greg; Wiljer, David; Miller, Robert C.; Gietema, Jourik A.; van Leeuwen, Flora E.; Williams, Jacqueline P.; Nichols, Craig R.; Einhorn, Lawrence H.; Fossa, Sophie D.

    2010-01-01

    Testicular cancer represents the most curable solid tumor, with a 10-year survival rate of more than 95%. Given the young average age at diagnosis, it is estimated that effective treatment approaches, in particular, platinum-based chemotherapy, have resulted in an average gain of several decades of life. This success, however, is offset by the emergence of considerable long-term morbidity, including second malignant neoplasms, cardiovascular disease, neurotoxicity, nephrotoxicity, pulmonary toxicity, hypogonadism, decreased fertility, and psychosocial problems. Data on underlying genetic or molecular factors that might identify those patients at highest risk for late sequelae are sparse. Genome-wide association studies and other translational molecular approaches now provide opportunities to identify testicular cancer survivors at greatest risk for therapy-related complications to develop evidence-based long-term follow-up guidelines and interventional strategies. We review research priorities identified during an international workshop devoted to testicular cancer survivors. Recommendations include 1) institution of lifelong follow-up of testicular cancer survivors within a large cohort setting to ascertain risks of emerging toxicities and the evolution of known late sequelae, 2) development of comprehensive risk prediction models that include treatment factors and genetic modifiers of late sequelae, 3) elucidation of the effect(s) of decades-long exposure to low serum levels of platinum, 4) assessment of the overall burden of medical and psychosocial morbidity, and 5) the eventual formulation of evidence-based long-term follow-up guidelines and interventions. Just as testicular cancer once served as the paradigm of a curable malignancy, comprehensive follow-up studies of testicular cancer survivors can pioneer new methodologies in survivorship research for all adult-onset cancer. PMID:20585105

  9. 78 FR 4422 - National Cancer Institute; Notice of Closed Meeting

    Science.gov (United States)

    2013-01-22

    ... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel; The Role of..., Ph.D., Scientific Review Administrator, Special Review and Logistics Branch, Division of Extramural...

  10. The Changing Face of Hallucination Research: The International Consortium on Hallucination Research (ICHR) 2015 Meeting Report.

    Science.gov (United States)

    Thomas, Neil; Rossell, Susan L; Waters, Flavie

    2016-07-01

    This article reports on the Third Biennial Meeting of the International Consortium on Hallucinations Research, held in Melbourne, Australia, in October 2015. Following a public conference in which research findings were considered in relation to subjective experience and practice, 9 multidisciplinary working groups examined key current issues in progressing the conceptualization and research of hallucinations. Work group topics included: multicenter validation of the transdiagnostic and multimodal Questionnaire for Psychotic Experiences; development of an improved outcome measure for psychological therapies; the relationship between inhibition and hallucinations across multiple levels of explanation; hallucinations in relation to sleep phenomena; emotion and hallucinations; multiple interactions between the experience of self and hallucinations; interactions between language, auditory and memory networks; resting state networks including the default mode; and analyses arising from functional magnetic resonance imaging (fMRI) data-sharing. Major themes in hallucinations research identified during the meeting included (1) progression beyond the auditory verbal modality in schizophrenia to consider hallucinations across modalities and different populations; (2) development of new measures; (3) the central role of multisite collaboration through shared data collection and data pooling; (4) study of time-based and interactive models of hallucination; and (5) the need to increase the accessibility and availability of "real-life" interventions for people with persisting and distressing hallucinations. © The Author 2015. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  11. Scientific Advisory Panel to Meet on Cancer Potential of Glyphosate

    Science.gov (United States)

    The Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (SAP) will meet October 18-21, 2016, to consider and review a set of scientific issues being evaluated by the regarding EPA's evaluation

  12. 78 FR 66374 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2013-11-05

    ..., 08:00 a.m. to December 6, 2013, 01:00 p.m., Doubletree Hotel Bethesda, (Formerly Holiday Inn Select... times and location remain the same. The meeting is closed to the public. Dated: October 30, 2013...

  13. 78 FR 64228 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-28

    .... Additionally, the meeting location has changed to the Hilton Rockville Hotel, 1750 Rockville Pike, Rockville..., October 16, 2013, 04:00 p.m. to October 17, 2013, 05:00 p.m., Bethesda North Marriott Hotel & Conference...

  14. Postdoctoral Fellow | Center for Cancer Research

    Science.gov (United States)

    Highly motivated postdoctoral fellows sought to work on tumor immunology with a strong background in biology preferentially cellular immunology. The tumor immunology group in the laboratory is exploring mechanisms of improving vaccines and immunotherapy for cancer, especially by discovering new principles to enhance and steer T cell immune responses. The group is focusing on negative immunoregulatory mechanisms used for immune evasion by cancer cells. The postdoctoral fellow will work on a project to understand the negative regulatory mechanisms of tumor immunity especially the mechanisms initiated by NKT cells. Group members also have an opportunity to gain knowledge of HIV/mucosal immunology by interacting with the HIV research group in the lab.

  15. Statistical Analysis of Research Data | Center for Cancer Research

    Science.gov (United States)

    Recent advances in cancer biology have resulted in the need for increased statistical analysis of research data. The Statistical Analysis of Research Data (SARD) course will be held on April 5-6, 2018 from 9 a.m.-5 p.m. at the National Institutes of Health's Natcher Conference Center, Balcony C on the Bethesda Campus. SARD is designed to provide an overview on the general principles of statistical analysis of research data.  The first day will feature univariate data analysis, including descriptive statistics, probability distributions, one- and two-sample inferential statistics.

  16. Cancer Core Europe: a consortium to address the cancer care-cancer research continuum challenge.

    Science.gov (United States)

    Eggermont, Alexander M M; Caldas, Carlos; Ringborg, Ulrik; Medema, René; Tabernero, Josep; Wiestler, Otmar

    2014-11-01

    European cancer research for a transformative initiative by creating a consortium of six leading excellent comprehensive cancer centres that will work together to address the cancer care-cancer research continuum. Prerequisites for joint translational and clinical research programs are very demanding. These require the creation of a virtual single 'e-hospital' and a powerful translational platform, inter-compatible clinical molecular profiling laboratories with a robust underlying computational biology pipeline, standardised functional and molecular imaging, commonly agreed Standard Operating Procedures (SOPs) for liquid and tissue biopsy procurement, storage and processing, for molecular diagnostics, 'omics', functional genetics, immune-monitoring and other assessments. Importantly also it requires a culture of data collection and data storage that provides complete longitudinal data sets to allow for: effective data sharing and common database building, and to achieve a level of completeness of data that is required for conducting outcome research, taking into account our current understanding of cancers as communities of evolving clones. Cutting edge basic research and technology development serve as an important driving force for innovative translational and clinical studies. Given the excellent track records of the six participants in these areas, Cancer Core Europe will be able to support the full spectrum of research required to address the cancer research- cancer care continuum. Cancer Core Europe also constitutes a unique environment to train the next generation of talents in innovative translational and clinical oncology. Copyright © 2014. Published by Elsevier Ltd.

  17. 77 FR 5029 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2012-02-01

    ... Community; Cancer Drug Shortages: Economic, Regulatory, and Manufacturing Issues; The Role of the Cancer... security, NIH has instituted stringent procedures for entrance onto the NIH campus. All visitor vehicles, including taxicabs, hotel, and airport shuttles will be inspected before being allowed on campus. Visitors...

  18. Senior Clinician | Center for Cancer Research

    Science.gov (United States)

    The Center for Cancer Research (CCR), NCI, NIH, HHS is seeking to fill several Senior Clinician positions with outstanding oncologists with research experience and expertise in one of the following areas:  1) genitourinary malignancies, 2) thoracic malignancies; 3) gastrointestinal malignancies; 4) lymphomas; 5) pediatric cancers; or 6) genetic tumor predisposition syndromes. These positions are located at the NIH campus in Bethesda, Maryland. The NIH Clinical Center is the world’s largest research hospital which offers state-of-the-art facilities, collaborative opportunities, and core facilities for advanced technologies.  The Senior Clinician will have available resources including funding for clinical trials, nurse practitioners, research nurses, and patient care coordinators.  In addition, the senior clinician will have access to a robust clinical trials infrastructure including data management, training, protocol support office, regulatory support, information systems and technology, and data safety monitoring.  The CCR’s collaborative culture also offers research staff access to a wide array of intellectual and technological assets, including high-quality technology cores dedicated to pharmacokinetics/pharmacodynamics, protein chemistry, natural products chemistry, biophysics, mass spectrometry, imaging, microscopy, proteomics and genomics, bioinformatics/biostatistics, and flow cytometry.  For an overview of CCR, please visit http://ccr.cancer.gov/.  For more information contact Lori Holliday at hollidal@mail.nih.gov.

  19. In silico cancer research towards 3R.

    Science.gov (United States)

    Jean-Quartier, Claire; Jeanquartier, Fleur; Jurisica, Igor; Holzinger, Andreas

    2018-04-12

    Improving our understanding of cancer and other complex diseases requires integrating diverse data sets and algorithms. Intertwining in vivo and in vitro data and in silico models are paramount to overcome intrinsic difficulties given by data complexity. Importantly, this approach also helps to uncover underlying molecular mechanisms. Over the years, research has introduced multiple biochemical and computational methods to study the disease, many of which require animal experiments. However, modeling systems and the comparison of cellular processes in both eukaryotes and prokaryotes help to understand specific aspects of uncontrolled cell growth, eventually leading to improved planning of future experiments. According to the principles for humane techniques milestones in alternative animal testing involve in vitro methods such as cell-based models and microfluidic chips, as well as clinical tests of microdosing and imaging. Up-to-date, the range of alternative methods has expanded towards computational approaches, based on the use of information from past in vitro and in vivo experiments. In fact, in silico techniques are often underrated but can be vital to understanding fundamental processes in cancer. They can rival accuracy of biological assays, and they can provide essential focus and direction to reduce experimental cost. We give an overview on in vivo, in vitro and in silico methods used in cancer research. Common models as cell-lines, xenografts, or genetically modified rodents reflect relevant pathological processes to a different degree, but can not replicate the full spectrum of human disease. There is an increasing importance of computational biology, advancing from the task of assisting biological analysis with network biology approaches as the basis for understanding a cell's functional organization up to model building for predictive systems. Underlining and extending the in silico approach with respect to the 3Rs for replacement, reduction and

  20. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... 2013 Media Resources Media Contacts Multicultural Media Events Scientific Meetings & Lectures Conferences Advisory Board Meetings Social Media Cancer Currents Blog About NCI NCI Overview History Contributing to Cancer Research Leadership Director's Page Deputy Director's Page Previous NCI ...

  1. Translating basic research in cancer patient care

    Directory of Open Access Journals (Sweden)

    Marcello Maugeri-Saccà

    2011-01-01

    Full Text Available With the advent of molecular targeted therapies and the development of high-throughput biotechnologies, it has become evident that progress in cancer research is largely due to the creation of multidisciplinary teams able to plan clinical trials supported by appropriate molecular hypotheses. These efforts have culminated in the identification and validation of biomarkers predictive of response, as well as in the generation of more accurate prognostic tools. The identification of cancer stem cells has provided further insights into mechanisms of cancer, and many studies have tried to translate this biological notion into prognostic and predictive information. In this regard, new agents targeting key stemness-related pathways have entered the clinical development, and preliminary data suggested an encouraging antitumor activity.

  2. The African Organization for Research and Training in Cancer: historical perspective.

    Science.gov (United States)

    Mohammed, S I; Williams, C K; Ndom, P; Holland, J F

    2012-10-01

    The African Organization for Research and Training in Cancer (aortic) is a bilingual (English and French) nonprofit organization dedicated to the promotion of cancer control and palliation in Africa. Its mission in respect to cancer control in Africa includes support of research and training;provision of relevant and accurate information on the prevention, early diagnosis, treatment, and palliation of cancer;promotion of public awareness about cancer and reduction of the stigma associated with it.In seeking to achieve its goal of cancer control in Africa, aortic strives to unite the continent and to make a positive impact throughout the region by collaboration with health ministries and global cancer organizations. The organization's key objectives are to further research relating to cancers prevalent in Africa, to support training programs in oncology for health care workers, to deal with the challenges of creating cancer control and prevention programs, and to raise public awareness of cancer in Africa. It also plans to organize symposia, workshops, meetings, and conferences that support its mission.Founded in September 1982, aortic was active only between 1983 (when its inaugural conference was held in the City of Lome, Togo, West Africa) and the late 1980s. The organization subsequently became inactive and moribund. In 2000, a group of expatriate African physicians and scientists joined in an effort with their non-African friends and colleagues to reactivate the dormant organization. Since its reactivation, aortic has succeeded in putting cancer on the public health agenda in many African countries by highlighting Africa's urgent need for cancer control and by holding meetings every two years in various African cities. National and international cancer control organizations worldwide have recognized the challenges facing Africa and have joined in aortic's mission.

  3. International Meeting on Needs and Challenges in Translational Medicine: filling the gap between basic research and clinical applications. Book of abstract

    International Nuclear Information System (INIS)

    Moretti, F.; Belardelli, F.; Romero, M.

    2008-01-01

    This multidisciplinary international meeting is organized by the Istituto Superiore di Sanita, in collaboration with Alleanza Contro il Cancro (Alliance Against Cancer, the Network of the Italian Comprehensive Cancer Centres) and EATRIS (European Advanced Translational Research Infrastructure in Medicine). The primary goal of the meeting is to provide a scientific forum to discuss the recent progress in translational research. Moreover, a particular focus will be devoted to the identification of needs, obstacles and new opportunities to promote translational research in biomedicine. The scientific programme will cover a broad range of fields including: cancer; neurosciences; rare diseases; cardiovascular diseases and infectious and autoimmune diseases. Furthermore, special attention will be given to the discussion of how comprehensive initiatives for addressing critical regulatory issues for First-In-Man - Phase I clinical studies can potentially improve the efficiency and quality of biomedical and translational research at an international level [it

  4. Ecology meets cancer biology: The cancer swamp promotes the lethal cancer phenotype

    Science.gov (United States)

    Amend, Sarah R.; Pienta, Kenneth J.

    2015-01-01

    As they grow, tumors fundamentally alter their microenvironment, disrupting the homeostasis of the host organ and eventually the patient as a whole. Lethality is the ultimate result of deregulated cell signaling and regulatory mechanisms as well as inappropriate host cell recruitment and activity that lead to the death of the patient. These processes have striking parallels to the framework of ecological biology: multiple interacting ecosystems (organ systems) within a larger biosphere (body), alterations in species stoichiometry (host cell types), resource cycling (cellular metabolism and cell-cell signaling), and ecosystem collapse (organ failure and death). In particular, as cancer cells generate their own niche within the tumor ecosystem, ecological engineering and autoeutrophication displace normal cell function and result in the creation of a hypoxic, acidic, and nutrient-poor environment. This “cancer swamp” has genetic and epigenetic effects at the local ecosystem level to promote metastasis and at the systemic host level to induce cytokine-mediated lethal syndromes, a major cause of death of cancer patients. PMID:25895024

  5. 76 FR 20335 - Meeting of the Strategic Environmental Research and Development Program, Scientific Advisory Board

    Science.gov (United States)

    2011-04-12

    ... DEPARTMENT OF DEFENSE Office of the Secretary Meeting of the Strategic Environmental Research and Development Program, Scientific Advisory Board AGENCY: Department of Defense. ACTION: Notice. SUMMARY: This...-463). The topic of the meeting on June 16, 2011 is to review continuing research and development...

  6. 76 FR 49753 - Strategic Environmental Research and Development Program Scientific Advisory Board Meeting

    Science.gov (United States)

    2011-08-11

    ... DEPARTMENT OF DEFENSE Office of the Secretary Strategic Environmental Research and Development Program Scientific Advisory Board Meeting AGENCY: Department of Defense. ACTION: Notice. SUMMARY: This...-463). The topic of the meeting on October 12-13, 2011 is to review new start research and development...

  7. 76 FR 71581 - National Human Genome Research Institute; Amended Notice of Meeting

    Science.gov (United States)

    2011-11-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome Research Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Human Genome Research Institute Special Emphasis Panel, November 22, 2011, 12 p.m. to November 22...

  8. 77 FR 67385 - National Human Genome Research Institute; Amended Notice of Meeting

    Science.gov (United States)

    2012-11-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome Research Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Human Genome Research Institute Special Emphasis Panel, October 29, 2012, 8:00 a.m. to October 30...

  9. 78 FR 65342 - National Human Genome Research Institute; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-31

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome Research Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Human Genome Research Institute Special Emphasis Panel, October 17, 2013, 08:00 a.m. to October 17...

  10. 77 FR 55853 - National Human Genome Research Institute; Amended Notice of Meeting

    Science.gov (United States)

    2012-09-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome Research Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Advisory Council for Human Genome Research, September 10, 2012, 8:30 a.m. to September 11, 2012, 5...

  11. 77 FR 27471 - National Human Genome Research Institute Amended Notice of Meeting

    Science.gov (United States)

    2012-05-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome Research Institute Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Advisory Council for Human Genome Research, May 21, 2012, 8:30 a.m. to May 22, 2012, 5:00 p.m...

  12. 76 FR 65738 - National Human Genome Research Institute; Amended Notice of Meeting

    Science.gov (United States)

    2011-10-24

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome Research Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Human Genome Research Institute Special Emphasis Panel, November 29, 2011, 8 a.m. to November 29...

  13. First IAEA research co-ordination meeting on 'Tritium inventory in fusion reactors'. Summary report

    International Nuclear Information System (INIS)

    Clark, R.E.H.

    2003-02-01

    The proceedings and conclusions of the first Research Co-ordination Meeting on 'Tritium Inventory in Fusion Reactors', held on November 4-6, 2002 at the IAEA Headquarters in Vienna are briefly described. This report includes a summary of the presentations made by the meeting participants and the specific goals set by the participants of the Co-ordinated Research Project (CRP). (author)

  14. 77 FR 19674 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-04-02

    ... commercial property such as patentable material, and personal information concerning individuals associated... and evaluate grant applications. Place: Doubletree Hotel Bethesda, 8120 Wisconsin Avenue, Bethesda, MD... Institute Special Emphasis Panel; Innovative Molecular Analysis Technologies for Cancer (R21). Date: June 26...

  15. Summary of the 8th Annual Bladder Cancer Think Tank: Collaborating to move research forward.

    Science.gov (United States)

    Apolo, Andrea B; Hoffman, Vanessa; Kaag, Matthew G; Latini, David M; Lee, Cheryl T; Rosenberg, Jonathan E; Knowles, Margaret; Theodorescu, Dan; Czerniak, Bogdan A; Efstathiou, Jason A; Albert, Matthew L; Sridhar, Srikala S; Margulis, Vitaly; Matin, Surena F; Galsky, Matthew D; Hansel, Donna; Kamat, Ashish M; Flaig, Thomas W; Smith, Angela B; Messing, Edward; Zipursky Quale, Diane; Lotan, Yair

    2015-02-01

    The 8th Annual Bladder Cancer Think Tank (BCAN-TT) brought together a multidisciplinary group of clinicians, researchers, and patient advocates in an effort to advance bladder cancer research. With the theme of "Collaborating to Move Research Forward," the meeting included three panel presentations and seven small working groups. The panel presentations and interactive discussions focused on three main areas: gender disparities, sexual dysfunction, and targeting novel pathways in bladder cancer. Small working groups also met to identify projects for the upcoming year, including: (1) improving enrollment and quality of clinical trials; (2) collecting data from multiple institutions for future research; (3) evaluating patterns of care for non-muscle-invasive bladder cancer; (4) improving delivery of care for muscle-invasive disease; (5) improving quality of life for survivors; (6) addressing upper tract disease; and (7) examining the impact of health policy changes on research and treatment of bladder cancer. The goal of the BCAN-TT is to advance the care of patients with bladder cancer and to promote collaborative research throughout the year. The meeting provided ample opportunities for collaboration among clinicians from multiple disciplines, patients and patient advocates, and industry representatives. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. Eurocan plus report: feasibility study for coordination of national cancer research activities.

    Science.gov (United States)

    2008-01-01

    The EUROCAN+PLUS Project, called for by the European Parliament, was launched in October 2005 as a feasibility study for coordination of national cancer research activities in Europe. Over the course of the next two years, the Project process organized over 60 large meetings and countless smaller meetings that gathered in total over a thousand people, the largest Europe-wide consultation ever conducted in the field of cancer research.Despite a strong tradition in biomedical science in Europe, fragmentation and lack of sustainability remain formidable challenges for implementing innovative cancer research and cancer care improvement. There is an enormous duplication of research effort in the Member States, which wastes time, wastes money and severely limits the total intellectual concentration on the wide cancer problem. There is a striking lack of communication between some of the biggest actors on the European scene, and there are palpable tensions between funders and those researchers seeking funds.It is essential to include the patients' voice in the establishment of priority areas in cancer research at the present time. The necessity to have dialogue between funders and scientists to establish the best mechanisms to meet the needs of the entire community is evident. A top priority should be the development of translational research (in its widest form), leading to the development of effective and innovative cancer treatments and preventive strategies. Translational research ranges from bench-to-bedside innovative cancer therapies and extends to include bringing about changes in population behaviours when a risk factor is established.The EUROCAN+PLUS Project recommends the creation of a small, permanent and independent European Cancer Initiative (ECI). This should be a model structure and was widely supported at both General Assemblies of the project. The ECI should assume responsibility for stimulating innovative cancer research and facilitating processes

  17. Immunotherapy: A breakthrough in cancer research

    Directory of Open Access Journals (Sweden)

    Editorial Office

    2016-12-01

    test the effectiveness of the tuberculosis vaccine Bacille Calmette-Guérin (BCG in treating superficial bladder cancer. The BCG treatment, in which BCG bacilli are inserted directly into a patient’s bladder via a catheter, proved to be an effective form of immunotherapy and the groundbreaking technique is still used today. In general, studies on immunotherapy have presented researchers with two important conclusions: First and foremost, researchers were finally able to prove that the immune system is indeed capable of recognizing cancer cells as a ‘foreign entity’ although they originate from the body’s own tissues. Secondly, by boosting the immune response, researchers are able to enhance other cancer-killing agents at the same time, thus increasing the chances of a successful treatment via immunotherapy. Based on these conclusions, researchers all over the world now face the challenge of figuring out which therapy works best for a specific type of cancer and why some cancer patients respond better than others to the prescribed treatments.At the ESMO Asia 2016 congress, lead author Dr. Makoto Tahara presented his paper ‘Asian head and neck cancer patients live longer with immunotherapy than mixed race group’, in which his team of researchers reported the sub-analysis results on the safety and efficacy of pembrolizumab in 26 patients (of Asian Pacific origin who received a fixed dose of the humanized antibody for 24 months until the detection of disease progression or adverse events. They observed that both the median overall survival and the disease control rate were better in Asians than the overall population, i.e. 11.5 versus 8.4 months and 50.5% versus 37.9%, respectively.According to Dr. Tahara, “The fixed dose of pembrolizumab was well-tolerated in Asian Pacific patients with recurrent/metastatic head and neck cancer. Although the Asian population was small, our findings suggest that they have better median overall survival with pembrolizumab than

  18. 75 FR 9001 - Advisory Committee for Environmental Research and Education; Notice of Meeting

    Science.gov (United States)

    2010-02-26

    ... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... support for environmental research and education. Agenda March 18, 2010 Update on recent NSF environmental... National Science Foundation announces the following meeting: Name: Advisory Committee for Environmental...

  19. 2015 NIEHS/EPA Children's Environmental Health and Disease Prevention Research Centers Annual Meeting

    Science.gov (United States)

    The meeting will feature the researchers and senior scientists from the Children's Centers, the PEHSUs, scientists from federal agencies and others through interdisciplinary presentations and discussions that explore connections between research findings,

  20. 76 FR 28056 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-05-13

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Counselors, National Human Genome Research Institute. The meeting will be closed to the public as indicated... National Human Genome Research Institute, including consideration of personnel qualifications and...

  1. 78 FR 70063 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2013-11-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Counselors, National Human Genome Research Institute. The meeting will be closed to the public as indicated... NATIONAL HUMAN GENOME RESEARCH INSTITUTE, including consideration of personnel qualifications and...

  2. 75 FR 13558 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-03-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Counselors, National Human Genome Research Institute. The meeting will be closed to the public as indicated... National Human Genome Research Institute, including consideration of personnel qualifications and...

  3. Meetings 'Nuclear, radiations and health' 2013 - news on cancers and ionizing radiations

    International Nuclear Information System (INIS)

    Grall, Yvon

    2013-03-01

    The author proposes a synthesis of a meeting on cancers and ionizing radiations. The contributions discussed advances on the understanding of radio-induced carcinogenesis. Interveners notably discussed deterministic and stochastic effects, current works on gene sequencing, and the occurrence of cancers after radiotherapy. Another contribution dealt with aggregates of leukaemia around nuclear stations and discussed epidemiological data. The second part of the meeting addressed radio-induced carcinogenesis and the effect of low doses. The issue of harmfulness of these low doses was discussed, notably in terms of occurrence of DNA lesions. The author then briefly reports the content of a round table which gathered all the contributors

  4. Determinants of variable resource use for multidisciplinary team meetings in cancer care

    DEFF Research Database (Denmark)

    Alexandersson, Nathalie; Rosell, Linn; Wihl, Jessica

    2018-01-01

    BACKGROUND: Multidisciplinary team meetings (MDTMs) have developed into standard of care to provide expert opinion and to grant evidence-based recommendations on diagnostics and treatment of cancer. Though MDTMs are associated with a range of benefits, a growing number of cases, complex case...... influenced by cancer diagnosis, hospital type and use of video facilities. When preparatory work, participation and post-MDTM work were considered, physicians spent mean 4.1 h per meeting. The cost per case discussion was mean 212 (range 91-595) EUR and the cost per MDTM was mean 2675 (range 1439-4070) EUR...

  5. 78 FR 58322 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2013-09-23

    ... Institute Special Emphasis Panel, November 06, 2013, 06:30 p.m. to November 07, 2013, 04:00 p.m., Hilton... August 16, 2013, 78 FR 50065. The meeting notice is amended to change the location from the Hilton...

  6. 78 FR 16274 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2013-03-14

    .... Date: April 23-24, 2013. Time: 8:30 a.m. to 1:00 p.m. Agenda: Challenges of Global HPV Vaccination... include the name, address, telephone number and when applicable, the business or professional affiliation... meeting will be posted when available. (Catalogue of Federal Domestic Assistance Program Nos. 93.392...

  7. 78 FR 66029 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2013-11-04

    ..., October 03, 2013, 08:00 a.m. to October 04, 2013, 05:00 p.m., Hilton Rockville Hotel, 1750 Rockville Pike... location remains the same. The meeting is closed to the public. Dated: October 29, 2013. Melanie J. Gray...

  8. 78 FR 66021 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2013-11-04

    ..., October 01, 2013, 08:00 a.m. to October 02, 2013, 05:00 p.m., Bethesda Marriott Hotel, 5151 Pooks Hill... location remain the same. The meeting is closed to the public. Dated: October 29, 2013. Melanie J. Gray...

  9. 75 FR 44274 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2010-07-28

    ..., October 21, 2010, 8 a.m. to October 21, 2010, 5 p.m., Doubletree Hotel Bethesda, (Formerly Holiday Inn..., 2010, 75 FR 39547. This FRN amendment has been processed to change the location of this meeting from the Doubletree Hotel Bethesda, 8120 Wisconsin Avenue, Bethesda MD 20814 to the Legacy Hotel and...

  10. 75 FR 79009 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2010-12-17

    .... This notice is amending the location of the meeting from the Doubletree Hotel Bethesda, 8120 Wisconsin... Therapeutics Program (NExT), January 6, 2011, 8:30 a.m.-4:30 p.m., Doubletree Hotel Bethesda, 8120 Wisconsin...

  11. 78 FR 64958 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-30

    ... from 4:00 p.m. to 5:00 p.m. Additionally, the meeting location has changed to Hilton Rockville Hotel..., October 15, 2013, 4:00 p.m. to October 16, 2013, 5:00 p.m., Bethesda North Marriott Hotel & Conference...

  12. Interdisciplinary Research Training in Breast Cancer

    Science.gov (United States)

    2005-07-01

    O’Sullivan’s background in surgical nursing has been valuable in facilitating improvements related to wound healing and infection after ovarian cancer surgery...Scientific Sessions of the Eastern Nursing Research Society, Boston, MA. Presentations "* Presenter, "Reiki for Self- Healing ," New Beginnings... Alzheimers Care Quarterly. (in press) "* Cherlin, E., Johnson-Hurzeler, R., Fried, T., Prigerson, H., Schulman-Green, D., Bradley, E.H. Communication between

  13. Combined modality therapy for thoracic and head and neck cancers: a review of updated literature based on a consensus meeting.

    Science.gov (United States)

    Franco, Pierfrancesco; Fiorentino, Alba; Dionisi, Francesco; Fiore, Michele; Chiesa, Silvia; Vagge, Stefano; Cellini, Francesco; Caravatta, Luciana; Tombolini, Mario; De Rose, Fiorenza; Meattini, Icro; Mortellaro, Gianluca; Apicella, Giuseppina; Marino, Lorenza; Greto, Daniela

    2016-10-13

    Combined modality therapy is a mainstay option for thoracic malignancies and head and neck cancers. The integration of different strategies is based on the multidisciplinary approach of modern clinical oncology. Radiation oncologists have to be educated, trained, and updated to provide state-of-the-art care to cancer patients and thus educational meetings are crucial. The Italian Association of Radiation Oncology Young Members Working Group (AIRO Giovani) organized its 8th national meeting, focused on combination therapy in lung, esophageal, and head and neck cancer (with a specific focus on larynx-preservation strategies for larynx/hypopharynx tumors), involving young professionals working in Italy. The meeting was addressed to young radiation oncologists, presenting state-of-the-art knowledge, based on the latest evidence in this field. We performed a review of the current literature based on the highlights of the Congress. The multimodality approach of head and neck and thoracic malignancies includes surgery, chemotherapy, and radiotherapy, but also has to take into account new information and data coming from basic and translational research and including molecular biology, genetics, and immunology. All these aspects are crucial for the treatment of non-small-cell lung cancer and esophageal, esophagogastric junction, and larynx/hypopharynx malignancies. The integration of different treatments in the clinical decision-making process to combine therapies is crucial. Combination therapy has proved to be a consolidated approach in these specific oncologic settings, highlighting the importance of multimodality management in modern clinical oncology. Dedicated meetings on specific topics are helpful to improve knowledge and skills of young professionals in radiation oncology.

  14. Basic and technical research on lung cancer

    International Nuclear Information System (INIS)

    Miyamoto, Tadaaki

    2004-01-01

    In association with clinical study of carbon beam therapy for lung cancer, the basic research for lung cancer and the patients with this disease has been carried out for the past 10 years. With regard to lung damage by the carbon beams, firstly pulmonary function was measured and analyzed for the patients with stage I non-small cell lung cancer. Force expiratory volume in 1 second (FVE 1.0) and TLC (total lung capacity) was found to be reduced significantly at 6 and 12 months after therapy but the reduction rate was a little, which can support the safety of this treatment modality. Secondly, the regional lung damage by the beams was investigated by using correct fusion of CT images with carbon beam dose distribution, diagnostic follow-up CT images and blood flow and ventilation spect images. It demonstrated the graded decrease blood flow by dose and the compensatory increase of blood flow in the adjacent lobe of lung unexposed to irradiation. On the other hand, the biological study of carbon beam effects on lung cancer cells and tumors line was conducted. Firstly, by using 7 or 4 human lung cancer cell line, the radiosensitivity of carbon beams was compared with that of photons by different histological patterns. It was found that there was no essential difference in the sensitivity pattern for lung cancer histology between the carbon beams and photons though the former doubled the later in power. Secondly, by using IA cell lines among them, the dynamic of clonogenic cells (clonogen) in a nude tumor and the changes in its morphology following irradiation was investigated, clarifying that the clonogen proliferating under anoxic or hypoxic conditions played a pivotal role for tumor regrowth and stemmed from the different clone which had been genetically selected and developed under these conditions. The finding of clonogen becomes one of the evidence supporting the superiority of a single-dose radiotherapy to fractionated radiotherapy. (author)

  15. Monitoring Lung Cancer Screening Use and Outcomes at Four Cancer Research Network Sites.

    Science.gov (United States)

    Gould, Michael K; Sakoda, Lori C; Ritzwoller, Debra P; Simoff, Michael J; Neslund-Dudas, Christine M; Kushi, Lawrence H; Carter-Harris, Lisa; Feigelson, Heather Spencer; Minowada, George; Doria-Rose, V Paul

    2017-12-01

    Lung cancer screening registries can monitor screening outcomes and improve quality of care. To describe nascent lung cancer screening programs and share efficient data collection approaches for mandatory registry reporting in four integrated health care systems of the National Cancer Institute-funded Cancer Research Network. We documented the distinctive characteristics of lung cancer screening programs, and we provide examples of strategies to facilitate data collection and describe early challenges and possible solutions. In addition, we report preliminary data on use and outcomes of screening with low-dose computed tomography at each of the participating sites. Programs varied in approaches to confirming patient eligibility, ordering screening low-dose computed tomographic scans, and coordinating follow-up care. Most data elements were collected from structured fields in electronic health records, but sites also made use of standardized order templates, local procedure codes, identifiable hashtags in radiology reports, and natural language processing algorithms. Common challenges included incomplete documentation of tobacco smoking history, difficulty distinguishing between scans performed for screening versus diagnosis or surveillance, and variable adherence with use of standardized templates. Adherence with eligibility criteria as well as the accuracy and completeness of data collection appeared to depend at least partly on availability of personnel and other resources to support the successful implementation of screening. To maximize the effectiveness of lung cancer screening, minimize the burden of data collection, and facilitate research and quality improvement, clinical workflow and information technology should be purposefully designed to ensure that patients meet eligibility criteria and receive appropriate follow-up testing.

  16. Sentinel node biopsy for prostate cancer: report from a consensus panel meeting.

    Science.gov (United States)

    van der Poel, Henk G; Wit, Esther M; Acar, Cenk; van den Berg, Nynke S; van Leeuwen, Fijs W B; Valdes Olmos, Renato A; Winter, Alexander; Wawroschek, Friedhelm; Liedberg, Fredrik; Maclennan, Steven; Lam, Thomas

    2017-08-01

    To explore the evidence and knowledge gaps in sentinel node biopsy (SNB) in prostate cancer through a consensus panel of experts. A two-round Delphi survey among experts was followed by a consensus panel meeting of 16 experts in February 2016. Agreement voting was performed using the research and development project/University of California, Los Angeles Appropriateness Methodology on 150 statements in nine domains. The disagreement index based on the interpercentile range, adjusted for symmetry score, was used to assess consensus and non-consensus among panel members. Consensus was obtained on 91 of 150 statements (61%). The main outcomes were: (1) the results from an extended lymph node dissection (eLND) are still considered the 'gold standard', and sentinel node (SN) detection should be combined with eLND, at least in patients with intermediate- and high-risk prostate cancer; (2) the role of SN detection in low-risk prostate cancer is unclear; and (3) future studies should contain oncological endpoints as number of positive nodes outside the eLND template, false-negative and false-positive SN procedures, and recurrence-free survival. A high rate of consensus was obtained regarding outcome measures of future clinical trials on SNB (89%). Consensus on tracer technology was only obtained in 47% of statements, reflecting a need for further research and standardization in this area. The low-level evidence in the available literature and the composition of mainly SNB users in the panel constitute the major limitations of the study. Consensus on a majority of elementary statements on SN detection in prostate cancer was obtained.; therefore, the results from this consensus report will provide a basis for the design of further studies in the field. A group of experts identified evidence and knowledge gaps on SN detection in prostate cancer and its application in daily practice. Information from the consensus statements can be used to direct further studies. © 2017 The

  17. Manufacturing/Cell Therapy Specialist | Center for Cancer Research

    Science.gov (United States)

    Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and blood diseases and

  18. Major clinical research advances in gynecologic cancer in 2013

    OpenAIRE

    Suh, Dong Hoon; Kim, Jae-Weon; Kang, Sokbom; Kim, Hak Jae; Lee, Kyung-Hun

    2014-01-01

    In 2013, 10 topics were selected for major clinical research advances in gynecologic oncology; these included three topics regarding cervical cancer, three regarding ovarian cancer, two regarding endometrial cancer, and one each regarding breast cancer and radiation oncology. For cervical cancer, bevacizumab was first demonstrated to exhibit outstanding clinical efficacy in a recurrent, metastatic setting. Regarding cervical cancer screening, visual inspections with acetic acid in low-resourc...

  19. IGORR-IV: Proceedings of the fourth meeting of the International Group On Research Reactors

    International Nuclear Information System (INIS)

    Rosenbalm, K.F.

    1995-01-01

    The fourth meeting of the International Group on Research Reactors (IGORR-IV) was attended by was good 55 registered participants from 28 organizations in 13 countries, which compares well with the previous meetings. Twenty-nine papers were presented in five sessions over the two-day meeting. Session subjects were: Operating Research Reactors and Facility Upgrades; Research Reactors in Desin and Construction; Research, Development, and Analysis Results of Thermal Hydraulic Calculations, U 3 Si 2 Fuel Performance and Faibrication; Structural Materials Performance; Neutronics; Severe Accident analysis. Written versions of the papers or hard copies of the viewgraphs used are published in these Proceedings

  20. Hypothyroidism after cancer and the ability to meet reproductive goals among a cohort of young adult female cancer survivors.

    Science.gov (United States)

    Chin, Helen B; Jacobson, Melanie H; Interrante, Julia D; Mertens, Ann C; Spencer, Jessica B; Howards, Penelope P

    2016-01-01

    To determine whether developing hypothyroidism after cancer treatment is associated with a decreased probability of women being able to meet their reproductive goals. A population-based cohort study. Not applicable. A total of 1,282 cancer survivors, of whom 904 met the inclusion criteria for the analysis. None. Three outcomes that may indicate reduced fertility, which include failure to achieve desired family size, childlessness, and not achieving pregnancy after at least 6 months of regular unprotected intercourse. We used data from the Furthering Understanding of Cancer Health and Survivorship in Adult (FUCHSIA) Women's Study to examine the association between being diagnosed with hypothyroidism after cancer and meeting reproductive goals. After adjusting for age and other potential confounders, women reporting hypothyroidism after cancer treatment were twice as likely to fail to achieve their desired family size (adjusted odds ratio [aOR] 1.91; 95% confidence interval [CI], 1.09, 3.33) and be childless (aOR 2.13; 95% CI, 1.25, 3.65). They were also more likely to report having unprotected intercourse for at least 6 months without conceiving (aOR 1.37; 95% CI, 0.66, 2.83). Although cancer treatments themselves are gonadotoxic, it is important to consider other medical conditions such as hypothyroidism that occur after cancer treatment when counseling patients on the risks for impaired fertility or a shortened reproductive window. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  1. ICPC Pilots International Student Training, Paving a Path for Tomorrow’s Cancer Researchers | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The Office of Cancer Clinical Proteomics Research at the National Cancer Institute, part of the United States National Institutes of Health, is spearheading the preparationand training of the proteogenomic research workforce on an international scale.

  2. 77 FR 4052 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-01-26

    ... Person: Marvin L. Salin, Ph.D., Scientific Review Officer, Special Review and Logistics Branch, Division... Special Emphasis Panel, The Role of Microbial Metabolites in Cancer Prevention and Etiology. Date: March... Soldatenkov, M.D., Ph.D., Scientific Review Officer, Special Review and Logistics Branch, Division of...

  3. 78 FR 8156 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... proposals. Place: Bethesda North Marriott Hotel & Conference Center, Montgomery County Conference Center... Institute, NIH, 6116 Executive Blvd., Suite 703, Room 7072, Bethesda, md 20892-8329, 301-594-1408, Stoicaa2...

  4. 77 FR 68136 - National Cancer Institute Amended; Notice of Meeting

    Science.gov (United States)

    2012-11-15

    ... Regency Bethesda Hotel, Old Georgetown Room, One Metro Center, Bethesda, MD 20814. The NCAB ad hoc... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute..., Building 31C, Wing C, Conference Room 10, 31 Center Drive, Bethesda, MD 20892 which was published in the...

  5. 77 FR 49450 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-08-16

    ... Executive Blvd., Rockville, MD 20852, (Telephone Conference Call). Contact Person: Gerald G. Lovinger, Ph.D... and R01 applications in Lung, Skin, Ovarian, Pancreatic and Gastrointestinal Cancers. Date: September... Washington/Rockville, 1750 Rockville Pike, Rockville, MD 20852. Contact Person: Caron A Lyman, Ph.D...

  6. 78 FR 50068 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2013-08-16

    ... be open to the public, with attendance limited to space available. Individuals who plan to attend and.../Default.aspx . Directions/Parking For a map and directions, please visit http://ncifrederick.cancer.gov... (three flag poles in this lot). Space in the parking lot is somewhat limited, and street parking on...

  7. Breast cancer in pregnancy: recommendations of an international consensus meeting.

    NARCIS (Netherlands)

    Amant, F.; Deckers, S.; Calsteren, K. van; Loibl, S.; Halaska, M.; Brepoels, L.; Beijnen, J.; Cardoso, F.; Gentilini, O.; Lagae, L.; Mir, O.; Neven, P.; Ottevanger, N.; Pans, S.; Peccatori, F.; Rouzier, R.; Senn, H.J.; Struikmans, H.; Christiaens, M.R.; Cameron, D.; Bois, A. du

    2010-01-01

    PURPOSE: To provide guidance for clinicians about the diagnosis, staging and treatment of breast cancer occurring during an otherwise uncomplicated pregnancy. METHODS: An international expert Panel convened to address a series of questions identified by a literature review and personal experience.

  8. 76 FR 11800 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-03-03

    ... Emphasis Panel; Biosensors for Early Cancer Detection and Risk Assessment. Date: March 29, 2011. Time: 2 p.m. to 5 p.m. Agenda: To review and evaluate contract proposals. Place: National Institutes of Health...: Lalita D. Palekar, PhD, Scientific Review Officer, Special Review and Logistics Branch, Division of...

  9. Quantitative Image Informatics for Cancer Research (QIICR) | Informatics Technology for Cancer Research (ITCR)

    Science.gov (United States)

    Imaging has enormous untapped potential to improve cancer research through software to extract and process morphometric and functional biomarkers. In the era of non-cytotoxic treatment agents, multi- modality image-guided ablative therapies and rapidly evolving computational resources, quantitative imaging software can be transformative in enabling minimally invasive, objective and reproducible evaluation of cancer treatment response. Post-processing algorithms are integral to high-throughput analysis and fine- grained differentiation of multiple molecular targets.

  10. Meeting

    Indian Academy of Sciences (India)

    the Defence Minister, Government of India on some of his experiences in technology development in India. A summary of his lecture appears in this issue. In the afternoon the .... of steel armour for our Light Tank which has found wide application to meet the ... basic issues: how information is encoded in the structure of DNA ...

  11. Meeting

    Indian Academy of Sciences (India)

    1985-11-07

    Nov 7, 1985 ... Business Meeting of Fellows. Evening Lecture. Architecture of the universe- R Cowsik ... and technical capabilities to plan, design and build satellites for earth observations, such as. Bhaskara I and II have ... Water Resources Systems Planning-. Some case studies for India. Edited by. Mahesh C Chaturvedi ...

  12. A Federated Network for Translational Cancer Research Using Clinical Data and Biospecimens.

    Science.gov (United States)

    Jacobson, Rebecca S; Becich, Michael J; Bollag, Roni J; Chavan, Girish; Corrigan, Julia; Dhir, Rajiv; Feldman, Michael D; Gaudioso, Carmelo; Legowski, Elizabeth; Maihle, Nita J; Mitchell, Kevin; Murphy, Monica; Sakthivel, Mayurapriyan; Tseytlin, Eugene; Weaver, JoEllen

    2015-12-15

    Advances in cancer research and personalized medicine will require significant new bridging infrastructures, including more robust biorepositories that link human tissue to clinical phenotypes and outcomes. In order to meet that challenge, four cancer centers formed the Text Information Extraction System (TIES) Cancer Research Network, a federated network that facilitates data and biospecimen sharing among member institutions. Member sites can access pathology data that are de-identified and processed with the TIES natural language processing system, which creates a repository of rich phenotype data linked to clinical biospecimens. TIES incorporates multiple security and privacy best practices that, combined with legal agreements, network policies, and procedures, enable regulatory compliance. The TIES Cancer Research Network now provides integrated access to investigators at all member institutions, where multiple investigator-driven pilot projects are underway. Examples of federated search across the network illustrate the potential impact on translational research, particularly for studies involving rare cancers, rare phenotypes, and specific biologic behaviors. The network satisfies several key desiderata including local control of data and credentialing, inclusion of rich phenotype information, and applicability to diverse research objectives. The TIES Cancer Research Network presents a model for a national data and biospecimen network. ©2015 American Association for Cancer Research.

  13. Sexual Violence and HIV Transmission: Summary Proceedings of a Scientific Research Planning Meeting

    OpenAIRE

    Klot, Jennifer F.; Auerbach, Judith D.; Berry, Miranda R.

    2012-01-01

    This summarizes proceedings of a Scientific Research Planning Meeting on Sexual Violence and HIV transmission, convened by the Social Science Research Council on 19–20 March 2012 at the Greentree Foundation in New York. The Meeting brought together an interdisciplinary group of basic, clinical, epidemiological and social science researchers and policy makers with the aim of: (1) examining what is known about the physiology of sexual violence and its role in HIV transmission, acquisition and p...

  14. Is there a Benefit of Multidisciplinary Cancer Team Meetings for Patients with Gastrointestinal Malignancies?

    NARCIS (Netherlands)

    Basta, Yara L.; Baur, Onno L.; van Dieren, Susan; Klinkenbijl, Jean H. G.; Fockens, Paul; Tytgat, Kristien M. A. J.

    2016-01-01

    Multidisciplinary cancer team meetings are intended to optimize the diagnosis of a patient with a malignancy. The aim of this study was to assess the number of correct diagnoses formulated by the multidisciplinary team (MDT) and whether MDT decisions were implemented. In a prospective study, data of

  15. Determinants of variable resource use for multidisciplinary team meetings in cancer care.

    Science.gov (United States)

    Alexandersson, Nathalie; Rosell, Linn; Wihl, Jessica; Ohlsson, Björn; Steen Carlsson, Katarina; Nilbert, Mef

    2017-12-03

    Multidisciplinary team meetings (MDTMs) have developed into standard of care to provide expert opinion and to grant evidence-based recommendations on diagnostics and treatment of cancer. Though MDTMs are associated with a range of benefits, a growing number of cases, complex case discussion and an increasing number of participants raise questions on cost versus benefit. We aimed to determine cost of MDTMs and to define determinants hereof based on observations in Swedish cancer care. Data were collected through observations of 50 MDTMs and from questionnaire data from 206 health professionals that participated in these meetings. The MDTMs lasted mean 0.88 h and managed mean 12.6 cases with mean 4.2 min per case. Participants were mean 8.2 physicians and 2.9 nurses/other health professionals. Besides the number of cases discussed, meeting duration was also influenced by cancer diagnosis, hospital type and use of video facilities. When preparatory work, participation and post-MDTM work were considered, physicians spent mean 4.1 h per meeting. The cost per case discussion was mean 212 (range 91-595) EUR and the cost per MDTM was mean 2675 (range 1439-4070) EUR. We identify considerable variability in resource use for MDTMs in cancer care and demonstrate that 84% of the total cost is derived from physician time. The variability demonstrated underscores the need for regular and structured evaluations to ensure cost effective MDTM services.

  16. A Milestone in Cancer Research and Treatment in India

    Science.gov (United States)

    Tata Memorial Center is celebrating 75 years of leadership service towards cancer control and research in India. In honor of this anniversary, TMC is hosting A Conference of New Ideas in Cancer – Challenging Dogmas on February 26-28th, 2016 as part of its platinum jubilee events. CGH Director, Dr. Ted Trimble, will give a plenary talk: "Thinking Outside the Box in Cancer Research - Perspectives from the US NCI” in the session titled: Future of Cancer Research: US and European perspectives.

  17. Meeting the Sustainability Challenge in Research and Education

    NARCIS (Netherlands)

    Erlijn Eweg; Ivo Opstelten; Nadia Verdeyen

    2013-01-01

    HU University of Applied Sciences Utrecht (HU) initiated a sustainability program in 2010. A compelling vision, collaboration with external partners, interdisciplinary research and interweavement of research and education are important elements in this program. The scope of this paper is

  18. 75 FR 3742 - Medicare Program; Meeting of the Advisory Panel on Medicare Education; Cancellation of the...

    Science.gov (United States)

    2010-01-22

    ...: Meeting Location: Hilton Washington Hotel Embassy Row, 2015 Massachusetts Avenue, NW., Washington, DC...., Director Cancer Research, Whittingham Cancer Center at Norwalk Hospital; Dr. Carmen R. Green, Director...

  19. Proceedings of the international meeting on reduced enrichment for research and test reactors

    International Nuclear Information System (INIS)

    Tsuchihashi, Keichiro

    1984-05-01

    The purpose of the Meeting was to exchange and discuss the most up-to-date information on the progress of various programs related to research and test reactor core conversion from high enriched uranium to lower enriched uranium. The papers presented during the Meeting were divided into 9 sessions and one round able discussion which concluded the Meeting. The Sessions were: Program, Fuel Development, Fuel Fabrication, Irradiation testing, Safety Analysis, Special Reactor Conversion, Reactor Design, Critical Experiments, and Reprocessing and Spent Fuel Storage. Thus, topics of this Meeting were of a very wide range that was expected to result in information exchange valuable for all the participants in the RERTR program

  20. The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report

    NARCIS (Netherlands)

    Kager, L.; Whelan, J.; Dirksen, U.; Hassan, B.; Anninga, J.; Bennister, L.; Bovee, J.V.; Brennan, B.; Broto, J.M.; Brugieres, L.; Cleton-Jansen, A.M.; Copland, C.; Dutour, A.; Fagioli, F.; Ferrari, S.; Fiocco, M.; Fleuren, E.D.; Gaspar, N.; Gelderblom, H.; Gerrand, C.; Gerss, J.; Gonzato, O.; Graaf, W.T. van der; Hecker-Nolting, S.; Herrero-Martin, D.; Klco-Brosius, S.; Kovar, H.; Ladenstein, R.; Lancia, C.; Ledeley, M.C.; McCabe, M.G.; Metzler, M.; Myklebost, O.; Nathrath, M.; Picci, P.; Potratz, J.; Redini, F.; Richter, G.H.; Reinke, D.; Rutkowski, P.; Scotlandi, K.; Strauss, S.; Thomas, D; Tirado, O.M.; Tirode, F.; Vassal, G.; Bielack, S.S.

    2016-01-01

    This report summarizes the results of the 3rd Joint ENCCA-WP7, EuroSarc, EEC, PROVABES, and EURAMOS European Bone Sarcoma Network Meeting, which was held at the Children's Cancer Research Institute in Vienna, Austria on September 24-25, 2015. The joint bone sarcoma network meetings bring together

  1. 78 FR 7794 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-04

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee..., Office of Review, National Institute of Nursing Research, National Institutes of Health, 6701 Democracy...: National Institute of Nursing Research Special Emphasis Panel, Fellowship & Mentored Research Scientist...

  2. IGORR 6: Proceedings of the 6th meeting of the International Group On Research Reactors

    International Nuclear Information System (INIS)

    1998-01-01

    A total of 39 papers were presented in 4 technical sessions: operating research reactors (operation, upgrades, and refurbishments); operating research reactors (experience from systems for better future design); new research reactors and projects, workshop on cold neutron sources, and workshop on research and development needs. All the papers presented at the meeting are published in this Proceedings

  3. Aquatic invasive species: Lessons from cancer research

    Science.gov (United States)

    Sepulveda, Adam; Ray, Andrew; Al-Chokhachy, Robert K.; Muhlfeld, Clint C.; Gresswell, Robert E.; Gross, Jackson A.; Kershner, Jeffrey L.

    2014-01-01

    Aquatic invasive species are disrupting ecosystems with increasing frequency. Successful control of these invasions has been rare: Biologists and managers have few tools for fighting aquatic invaders. In contrast, the medical community has long worked to develop tools for preventing and fighting cancer. Its successes are marked by a coordinated research approach with multiple steps: prevention, early detection, diagnosis, treatment options and rehabilitation. The authors discuss how these steps can be applied to aquatic invasive species, such as the American bullfrog (Lithobates catesbeianus), in the Northern Rocky Mountain region of the United States, to expedite tool development and implementation along with achievement of biodiversity conservation goals.

  4. Cancer vaccines: from research to clinical practice

    National Research Council Canada - National Science Library

    Bot, Adrian; Obrocea, Mihail; Marincola, Francesco M

    2011-01-01

    ..., for both solid and blood borne cancers. Cancer Vaccines: Challenges and Opportunities in Translation is the first text in the field to bring immunotherapy treatments from the laboratory trial to the bedside for the practicing oncologist. Cancer Vaccines...

  5. Summer Student Breast Cancer Research Training Program

    National Research Council Canada - National Science Library

    Zaloga, Gary P

    2005-01-01

    ... projects addressed the effects of omega-3 lipids upon breast cancer cells. 0mega-3 lipids were found to decrease breast cancer-induced muscle cell proteolysis and to induce apoptosis in cancer cells...

  6. An overview of cancer research in South African academic and ...

    African Journals Online (AJOL)

    [1] Based on the most recent. South African National Cancer Registry data, 1 in 9 women and .... Research activity in the five most commonly diagnosed male and female cancers in SA was assessed. .... that there were no costing or costeffectiveness cancer research projects. However, it is possible that deskbased economic ...

  7. Annual technical meeting of the NRC cooperative severe accident research program

    International Nuclear Information System (INIS)

    Silver, E.G.

    1993-01-01

    This brief report summarizes the 1992 annual technical meeting of the NRC Cooperative Severe Accident Research Program (CSARP-92) held at the Hyatt Regency Hotel in Bethesda, Maryland, May 4-8, 1992. The report is taken mainly from coverage of the meeting published in the June 5, 1992, issue of Atomic Energy Clearinghouse. Results of this meeting are formalized at the Water Reactor Safety Information Meetings (WRSIM) that are held annually in October. Nuclear Safety summarizes the annual WRSIM meetings and provides a list of the presentations that were given. Interested readers are encouraged to review listed topics to identify specific topic areas in severe accident research. Sessions were held on in-vessel core melt progression; fuel-coolant interactions; fission-product behavior; direct containment heating; and severe accident code development, assessment, and validation. Summaries of the individual technical sessions and the current state of the art in these areas were given by the chairmen

  8. Research Summaries: The 11th Biennial Rivkin Center Ovarian Cancer Research Symposium.

    Science.gov (United States)

    Armstrong, Deborah K

    2017-11-01

    In September 2016, the 11th biennial ovarian cancer research symposium was presented by the Rivkin Center for Ovarian Cancer and the American Association for Cancer Research. The 2016 symposium focused on 4 broad areas of research: Mechanisms of Initiation and Progression of Ovarian Cancer, Tumor Microenvironment and Models of Ovarian Cancer, Detection and Prevention of Ovarian Cancer, and Novel Therapeutics for Ovarian Cancer. The presentations and abstracts from each of these areas are reviewed in this supplement to the International Journal of Gynecologic Oncology.

  9. 75 FR 31795 - Office of Biotechnology Activities; Recombinant DNA Research: Amended Notice of Meeting

    Science.gov (United States)

    2010-06-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities; Recombinant DNA Research: Amended Notice of Meeting ACTION: Notice of cancellation of... information. Dated: May 26, 2010. Jacqueline Corrigan-Curay, Acting Director, Office of Biotechnology...

  10. Selected National Cancer Institute Breast Cancer Research Topics | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... Cancer and Environment Research Centers (BCERCs) to conduct interdisciplinary research on the effects of early environmental exposures ... more than 20 cancers using state-of-the art genomic analysis technologies. Recent findings suggest that there ...

  11. meeting challenges in higher education and research and develop

    Indian Academy of Sciences (India)

    prvn

    2006-08-08

    Aug 8, 2006 ... professional edge (e.g., additional skill building that adds to employability) or research experience. We make several suggestions about how to achieve these. Of the large number of such people with a first degree, a small fraction (typically a sixth) go on to higher degree or research; the remainder, if well ...

  12. Postdoctoral Fellow | Center for Cancer Research

    Science.gov (United States)

    A postdoctoral fellowship is currently available for productive, highly-motivated, and energetic individuals in the Inflammation and Tumorigenesis Section of Dr. Yinling Hu at the NCI-Frederick campus.  A dynamic research environment and outstanding resources are available for enthusiastic individuals.  Requirements include a Ph.D., M.D., or equivalent degree and experience in Immunology, Molecular Biology, and/or Signaling Research. Candidate must have excellent verbal, written communication and organizational skills, and the ability to handle multiple projects simultaneously. The project will be to investigate mechanisms of IKK/NF-B-involved auto-immunity, infection, innate immunity in mouse models of carcinogenesis/cancer biology, tumor initiating cells, and lymphoid organ development.

  13. Meeting report: 28th International Conference on Antiviral Research in Rome, Italy.

    Science.gov (United States)

    Vere Hodge, R Anthony

    2015-11-01

    The 28th International Conference on Antiviral Research (ICAR) was held in Rome, Italy from May 11 to 15, 2015. This article summarizes the principal invited lectures. Phillip Furman, the Elion award recipient, described the research leading to sofosbuvir. Dennis Liotta, who received the Holý award, described how an investigation into HIV entry inhibitors led to a new therapy for cancer patients. Erica Ollmann Saphire, winner of the Prusoff Young Investigator award, explored the world of viral proteins and how they remodel to perform different essential roles in viral replication. The keynote addresses, by Raffaele De Francesco and Michael Manns, reported on the remarkable progress made in the therapy of chronic HCV infections. A third keynote address, by Armand Sprecher, related the difficulties and successes of Médicins Sans Frontières in West Africa ravaged by the Ebola outbreak. There were three mini-symposia on RNA Viruses, Antiviral Chemistry and Emerging Viruses. There was a good collection of talks on RNA viruses (norovirus, rabies, dengue, HEV, HCV, and RSV). A highlight of the chemistry was the preparation of prodrugs for nucleotide triphosphates as this opens a door to new options. The third mini-symposium emphasized how research work in the antiviral area is continuing to expand and needs to do so with a sense of urgency. Although this meeting report covers only a few of the presentations, it aims to illustrate the great diversity of topics discussed at ICAR, bringing together knowledge and expertise from the whole spectrum of antiviral research. Copyright © 2015. Published by Elsevier B.V.

  14. Published Research - NCI Alliance for Nanotechnology in Cancer

    Science.gov (United States)

    The NCI Alliance for Nanotechnology in Cancer has published much exciting and impactful research over the years. Find here a list of all of these listed in PubMed and others across the field of Cancer Nanotechnology.

  15. Proceedings of the Scientific Meeting on Research and Development of Isotopes Application and Radiation

    International Nuclear Information System (INIS)

    Singgih Sutrisno; Sofyan Yatim; Pattiradjawane, EIsje L.; Ismachin, Moch; Mugiono; Marga Utama; Komaruddin Idris

    2004-02-01

    The Proceedings of Scientific Meeting on Research and Development of Isotopes Application and Radiation has been presented on February 17-18, 2004 in Jakarta. The aims of the Meeting is to disseminate the results of research on application of nuclear techniques on agricultural, animal, industry, hydrology and environment. There were 4 invited papers and 38 papers from BATAN participants as well as outside. The articles are indexing separately. (PPIN)

  16. Announced document collection of the 3rd information exchange meeting on radioactive waste disposal research network

    International Nuclear Information System (INIS)

    2008-03-01

    The 3rd meeting on 'Radioactive Waste Disposal Research Network' was held at the Ricotti techno community square of JAEA on September 3 and 4, 2007. The 'Radioactive Waste Disposal Research Network' was established in Interorganization Atomic Energy Research Program under academic collaborative agreement between Japan Atomic Energy Agency and the University of Tokyo. The objective is to bring both research infrastructures and human expertise in Japan to an adequate performance level, thereby contributing to the development of the fundamental research area in the field of radioactive waste disposal. This lecture material is a collection of presentations and discussions during the information exchange meeting. (author)

  17. 75 FR 11894 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2010-03-12

    ... Judgment Budget, Board Discussion about Communicating with the Community about Genomics Research. Place..., 8:30 a.m. to 1 p.m. Agenda: Board Discussion about Engaging the Community around Genomics Research... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND...

  18. Cancer research meets tick vectors for infectious diseases

    Czech Academy of Sciences Publication Activity Database

    Cabezas-Cruz, A.; Valdés, James J.; de la Fuente, J.

    2014-01-01

    Roč. 14, č. 10 (2014), s. 916-917 ISSN 1473-3099 Institutional support: RVO:60077344 Keywords : protective immunity * IgE * responses * mice Subject RIV: EC - Immunology Impact factor: 22.433, year: 2014

  19. Building technology transfer meetings: A collaborative model for transferring DOE research results to potential users

    Energy Technology Data Exchange (ETDEWEB)

    Shankle, D.L.; Hawkins, D.M. [Pacific Northwest Lab., Richland, WA (United States); Love, P.M. [Oak Ridge National Lab., TN (United States); Wilde, G.M. [Lawrence Berkeley Lab., CA (United States)

    1994-08-01

    Transferring the technology and results from U.S. Department of Energy (DOE)-sponsored building energy research to potential users is a critical part of DOE`s successful research programs. To assist in this transfer of information and technologies, the DOE Office of Building Technologies (OBT) has established Building Technology Transfer Meetings that are held twice each year at one of the 10 DOE Regional Support Offices. Meeting participants include DOE personnel and representatives from each of the national laboratories involved in OBT buildings energy research as well as representatives from the DOE Regional Support Offices and other agencies involved in the buildings sector. Since 1991, OBT has held five meetings: Washington D.C., San Francisco, Denver, Oak Ridge, and Seattle. The purpose of these meetings is twofold: (1) for DOE to share information about such topics as new research results, new technologies, and new ways to collaborate with industry and universities to leverage resources; and (2) for the participants to use this information within their region to accelerate the transfer and deployment of new energy-efficient building technologies. The meetings include presentations, demonstrations, and tours. The meetings have provided an excellent opportunity for staff from the Regional Support Offices to learn about new technologies through their interactions with OBT and national laboratory program managers. Meeting tours and demonstrations have provided beneficial opportunities to get hands-on experience with new technologies and to see them in practice.

  20. Meet EPA Researcher Justin Conley, Ph.D.

    Science.gov (United States)

    Justin Conley is a postdoctoral researcher investigating the toxicity of endocrine disrupting chemicals and new approaches for water quality monitoring. When he is not in the lab, he is busy brewing beer and exploring the outdoors.

  1. Fox Chase Cancer Center's Genitourinary Division: a national resource for research, innovation and patient care.

    Science.gov (United States)

    Uzzo, Robert G; Horwitz, Eric M; Plimack, Elizabeth R

    2016-04-01

    Founded in 1904, Fox Chase Cancer Center remains committed to its mission. It is one of 41 centers in the country designated as a Comprehensive Cancer Center by the National Cancer Institute, is a founding member of the National Comprehensive Cancer Network, holds the magnet designation for nursing excellence, is one of the first to establish a family cancer risk assessment program, and has achieved national distinction because of the scientific discoveries made there that have advanced clinical care. Two of its researchers have won Nobel prizes. The Genitourinary Division is nationally recognized and viewed as one of the top driving forces behind the growth of Fox Chase due to its commitment to initiating and participating in clinical trials, its prolific contributions to peer-reviewed publications and presentations at scientific meetings, its innovations in therapies and treatment strategies, and its commitment to bringing cutting-edge therapies to patients.

  2. Online journalism meets the university: ideas for teaching and research

    OpenAIRE

    Salaverría, R. (Ramón)

    2011-01-01

    During the last decade, the teaching and research on online journalism has become widespread in journalism faculties throughout the world. Such development has brought many undergraduate and graduate courses on the issue, as well as a number of networks of researchers and specialized publications in many countries. Once this initial process is over, it is time to bring the discipline of online journalism to its maturity at the university. For this aim, the author proposes to switch the curren...

  3. Gaps in nutritional research among older adults with cancer.

    Science.gov (United States)

    Presley, Carolyn J; Dotan, Efrat; Soto-Perez-de-Celis, Enrique; Jatoi, Aminah; Mohile, Supriya G; Won, Elizabeth; Alibhai, Shabbir; Kilari, Deepak; Harrison, Robert; Klepin, Heidi D; Wildes, Tanya M; Mustian, Karen; Demark-Wahnefried, Wendy

    2016-07-01

    Nutritional issues among older adults with cancer are an understudied area of research despite significant prognostic implications for treatment side effects, cancer-specific mortality, and overall survival. In May of 2015, the National Cancer Institute and the National Institute on Aging co-sponsored a conference focused on future directions in geriatric oncology research. Nutritional research among older adults with cancer was highlighted as a major area of concern as most nutritional cancer research has been conducted among younger adults, with limited evidence to guide the care of nutritional issues among older adults with cancer. Cancer diagnoses among older adults are increasing, and the care of the older adult with cancer is complicated due to multimorbidity, heterogeneous functional status, polypharmacy, deficits in cognitive and mental health, and several other non-cancer factors. Due to this complexity, nutritional needs are dynamic, multifaceted, and dependent on the clinical scenario. This manuscript outlines the proceedings of this conference including knowledge gaps and recommendations for future nutritional research among older adults with cancer. Three common clinical scenarios encountered by oncologists include (1) weight loss during anti-cancer therapy, (2) malnutrition during advanced disease, and (3) obesity during survivorship. In this manuscript, we provide a brief overview of relevant cancer literature within these three areas, knowledge gaps that exist, and recommendations for future research. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. 75 FR 48411 - Research, Engineering and Development Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2010-08-10

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Research, Engineering and Development.... 2), notice is hereby given of a meeting of the FAA Research, Engineering and Development (R, E&D) Advisory Committee. Name: Research, Engineering & Development Advisory Committee. Time and Date: September...

  5. 78 FR 18680 - Rehabilitation Research and Development Scientific Merit Review Board, Notice of Meeting

    Science.gov (United States)

    2013-03-27

    ... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Scientific Merit Review... Service, and the Chief Research and Development Officer on the scientific and technical merit, the mission... Committee Act, 5 U.S.C. App. 2, that a meeting of the Rehabilitation Research and Development Service...

  6. 78 FR 6854 - Health Services Research and Development Service Scientific Merit Review Board; Notice of Meeting

    Science.gov (United States)

    2013-01-31

    ... DEPARTMENT OF VETERANS AFFAIRS Health Services Research and Development Service Scientific Merit... Research and Development Service Scientific Merit Review Board will meet on February 13-14, 2013, at the... research. Applications are reviewed for scientific and technical merit. Recommendations regarding funding...

  7. 76 FR 32978 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2011-06-07

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee..., Office of Review, National Inst of Nursing Research, National Institutes of Health, 6701 Democracy Blvd...: National Institute of Nursing Research Special Emphasis Panel, Heart Failure Palliative Care. Date: July 8...

  8. 77 FR 59199 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-26

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee...: Mario Rinaudo, MD, Scientific Review Officer, Office of Review, National Institute of Nursing Research..., [email protected] . Name of Committee: National Institute of Nursing Research Special Emphasis Panel...

  9. 76 FR 59413 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-26

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee..., National Institute of Nursing Research, National Institutes of Health, 6701 Democracy Blvd., Ste. 710... Review Administrator, National Institute of Nursing Research, National Institutes of Health, 6701...

  10. 78 FR 29373 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-20

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee... of Nursing Research, National Institutes of Health, 6701 Democracy Blvd., Ste. 710, Bethesda, MD 20892, (301) 594-5966, [email protected] . Name of Committee: National Institute of Nursing Research...

  11. 78 FR 52938 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-08-27

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Nursing Research, National Institutes of Health, 6701 Democracy Boulevard, Suite 710, Bethesda, MD 20892...

  12. 78 FR 14098 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-03-04

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Federal Domestic Assistance Program Nos. 93.361, Nursing Research, National Institutes of Health, HHS...

  13. 75 FR 10808 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2010-03-09

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research, Special... Nursing Research, National Institutes of Health, 6701 Democracy Blvd (DEM 1), Suite 710, Bethesda, MD...

  14. 77 FR 35991 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-06-15

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special...., Scientific Review Officer, National Institute of Nursing Research, National Institutes of Health, Bethesda...

  15. 77 FR 32652 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-06-01

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial..., [email protected] . (Catalogue of Federal Domestic Assistance Program Nos. 93.361, Nursing Research...

  16. 75 FR 49941 - National Institute of Nursing Research; Notice of Meeting

    Science.gov (United States)

    2010-08-16

    ... Nursing Research; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... for Nursing Research. Date: September 14-15, 2010 Open: September 14, 2010, 1 p.m. to 5 p.m. Agenda... Nos. 93.361, Nursing Research, National Institutes of Health, HHS) [[Page 49942

  17. 77 FR 6812 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-02-09

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, (301) 594-0343...

  18. 75 FR 20853 - National Institute of Nursing Research; Notice of Meeting

    Science.gov (United States)

    2010-04-21

    ... Nursing Research; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... for Nursing Research. Date: May 18-19, 2010. Open: May 18, 2010, 1 p.m. to 5 p.m. Agenda: Discussion... of Federal Domestic Assistance Program Nos. 93.361, Nursing Research, National Institutes of Health...

  19. 76 FR 5596 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2011-02-01

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial...: Weiqun Li, MD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  20. 76 FR 57068 - National Institute of Nursing Research Notice of Closed Meeting

    Science.gov (United States)

    2011-09-15

    ... Nursing Research Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Thyagarajan, PhD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  1. 75 FR 56118 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2010-09-15

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial...: Weiqun Li, MD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  2. 77 FR 76054 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-12-26

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... . (Catalogue of Federal Domestic Assistance Program Nos. 93.361, Nursing Research, National Institutes of...

  3. 77 FR 3481 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-01-24

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial...: Weiqun Li, MD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  4. 75 FR 55808 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2010-09-14

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Federal Domestic Assistance Program Nos. 93.361, Nursing Research, National Institutes of Health, HHS...

  5. 76 FR 77240 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2011-12-12

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee... Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, (301) 594-0343, [email protected] . Name of Committee: National Institute of Nursing Research Special Emphasis...

  6. 76 FR 571 - National Institute of Nursing Research; Notice of Meeting

    Science.gov (United States)

    2011-01-05

    ... Nursing Research; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... for Nursing Research. Date: January 18-19, 2011. Open: January 18, 2011, 1 p.m. to 4:45 p.m. Agenda... Domestic Assistance Program Nos. 93.361, Nursing Research, National Institutes of Health, HHS) Dated...

  7. 78 FR 63996 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-10-25

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial... Nos. 93.361, Nursing Research, National Institutes of Health, HHS) Dated: October 21, 2013. Michelle...

  8. 77 FR 12599 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-03-01

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Review Officer, Office of Review, National Inst of Nursing Research, National Institutes of Health, 6701...

  9. 77 FR 61418 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-10-09

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, (301) 594-0343...

  10. 76 FR 31621 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2011-06-01

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial...: Weiqun Li, MD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  11. 77 FR 3479 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-01-24

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special..., Office of Review, National Inst of Nursing Research, National Institutes of Health, 6701 Democracy Blvd...

  12. 78 FR 2276 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-01-10

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... Institute of Nursing Research, National Institutes of Health, 6701 Democracy Blvd., Ste. 710, Bethesda, MD..., Nursing Research, National Institutes of Health, HHS) Dated: January 4, 2013. Michelle Trout, Program...

  13. 76 FR 49779 - National Institute of Nursing Research Notice of Meeting

    Science.gov (United States)

    2011-08-11

    ... Nursing Research Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... for Nursing Research. Date: September 20-21, 2011. Open: September 20, 2011, 1 p.m. to 5 p.m. Agenda... Nos. 93.361, Nursing Research, National Institutes of Health, HHS) Dated: August 5, 2011. Jennifer S...

  14. 78 FR 63997 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-10-25

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special..., National Institute of Nursing Research, National Institutes of Health, 6701 Democracy Blvd., Suite 703K...

  15. 77 FR 59941 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-10-01

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial... 20814. Contact Person: Weiqun Li, MD, Scientific Review Officer, National Institute of Nursing Research...

  16. 77 FR 27075 - National Institute of Nursing Research Notice of Closed Meeting

    Science.gov (United States)

    2012-05-08

    ... Nursing Research Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Thyagarajan, Ph.D., Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  17. 76 FR 10912 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-28

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee.... [email protected] . Name of Committee: National Institute of Nursing Research Special Emphasis... of Review, National Inst of Nursing Research, National Institutes of Health, 6701 Democracy Blvd (DEM...

  18. 77 FR 33752 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2012-06-07

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee... Officer, Office of Review, National Inst. of Nursing Research, National Institutes of Health, 6701... Committee: National Institute of Nursing Research Special Emphasis Panel Fellowship and Career Award Grant...

  19. 76 FR 23828 - National Institute of Nursing Research; Notice of Meeting

    Science.gov (United States)

    2011-04-28

    ... Nursing Research; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... for Nursing Research. Date: May 17-18, 2011. Open: May 17, 2011, 1 p.m. to 5 p.m. Agenda: Discussion... available. (Catalogue of Federal Domestic Assistance Program Nos. 93.361, Nursing Research, National...

  20. 78 FR 73867 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-12-09

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special..., National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, 301-402-5807...

  1. 75 FR 1794 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2010-01-13

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special..., PhD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of Health...

  2. 78 FR 17420 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-03-21

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special..., Ph.D., Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  3. 75 FR 55808 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-14

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee..., Scientific Review Administrator, National Institute of Nursing Research, National Institutes of Health, 6701...: National Institute of Nursing Research Special Emphasis Panel; Informed-Decision Making in Young Adolescent...

  4. 76 FR 31621 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2011-06-01

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee..., National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, (301) 594-0343, [email protected] . Name of Committee: National Institute of Nursing Research Special Emphasis...

  5. 76 FR 60508 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2011-09-29

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial..., [email protected] . (Catalogue of Federal Domestic Assistance Program Nos. 93.361, Nursing Research...

  6. Summary report on first research coordination meeting on heavy charged-particle interaction data for radiotherapy

    International Nuclear Information System (INIS)

    Palmans, H.; Noy, R.C.

    2008-04-01

    A summary is given of the First Research Coordination Meeting on Heavy Charged-Particle Interaction Data for Radiotherapy. A programme to compile and evaluate charged-particle nuclear data for therapeutic applications was proposed. Detailed coordinated research proposals were also agreed. Technical discussions and the resulting work plan of the Coordinated Research Project are summarized, along with actions and deadlines. (author)

  7. Thinking Big Picture: Meeting the Needs of Researchers in Northern Australia

    Science.gov (United States)

    Mamtora, Jayshree

    2011-01-01

    Due to the increase in research activity at Charles Darwin University in recent years, the Library created the position of Research Services Coordinator to meet researcher needs. Eighteen months after the new staff member was in place, an online survey was carried out to gauge the success of the new services and resources provided, and thereby…

  8. 78 FR 20696 - NASA Advisory Council; Human Exploration and Operations Committee; Research Subcommittee; Meeting

    Science.gov (United States)

    2013-04-05

    ... Exploration and Operations Committee; Research Subcommittee; Meeting AGENCY: National Aeronautics and Space... of the Research Subcommittee of the Human Exploration and Operations Committee (HEOC) of the NASA... organizing the activities of the Subcommittee and fact-finding with respect to the research activities within...

  9. 75 FR 2147 - National Human Genome Research Institute; Notice of Meetings

    Science.gov (United States)

    2010-01-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Council for Human Genome Research. The meetings will be open to the public as indicated below, with... Extramural Research, National Human Genome Research Institute, 5635 Fishers Lane, Suite 4076, MSC 9305...

  10. When electoral Paradigm meets the research Implications: The Youth Perspective

    Directory of Open Access Journals (Sweden)

    Mihálik Jaroslav

    2016-10-01

    Full Text Available The recent comprehensive research on youth attitudes to democratic governance, political leaders and civic participation has explored several patterns of electoral behaviour of young voters. The major domains of such include support for alternative political platforms, dissatisfaction with the democratic performance, rise of xenophobia and propensity to far-right politics and radical problem solutions. These trends have been, to some extent, visible during the electoral campaign and confirmed in the results, let alone the rise of extremist measures among young voters and their political support. The aim of the research paper is to confront the research data in Slovakia from two contrasting field sites with the electoral paradigms as interpreted from the electoral results and support for particular political parties and movements. We argue using the combined methodological approaches from quantitative surveys and in-depth individual interviews with young people from MYPLACE project and other research data to compare the research implications with the electoral results and related major themes.

  11. Online journalism meets the university: ideas for teaching and research

    Directory of Open Access Journals (Sweden)

    Ramón Salaverría

    2011-12-01

    Full Text Available During the last decade, the teaching and research on online journalism has become widespread in journalism faculties throughout the world. Such development has brought many undergraduate and graduate courses on the issue, as well as a number of networks of researchers and specialized publications in many countries. Once this initial process is over, it is time to bring the discipline of online journalism to its maturity at the university. For this aim, the author proposes to switch the current training model, which basically shows how to manage digital tools, to another broader one that teaches journalism principles and skills in an online environment. Regarding research, he suggests not to limit it to descriptive studies, but to develop also more analytical works that could better serve both the academic community and the online media professionals.

  12. ONLINE JOURNALISM MEETS THE UNIVERSITY: ideas for teaching and research

    Directory of Open Access Journals (Sweden)

    Ramón Salaverría

    2011-12-01

    Full Text Available During the last decade, the teaching and research on online journalism has become widespread in journalism faculties throughout the world. Such development has brought many undergraduate and graduate courses on the issue, as well as a number of networks of researchers and specialized publications in many countries. Once this initial process is over, it is time to bring the discipline of online journalism to its maturity at the university. For this aim, the author proposes to switch the current training model, which basically shows how to manage digital tools, to another broader one that teaches journalism principles and skills in an online environment. Regarding research, he suggests not to limit it to descriptive studies, but to develop also more analytical works that could better serve both the academic community and the online media professionals.

  13. 75 FR 38504 - Meetings of the Naval Research Advisory Committee

    Science.gov (United States)

    2010-07-02

    ... Commands (SYSCOMs) and Program Executive Offices (PEOs) (as well as the stewardship provided for those competencies and the technical core competencies that are provided by the Navy University Affiliated Research... than July 1, 2010, to: Mr. William Ellis, NRAC Program Director, [email protected] ; fax: 703-696...

  14. Research for global challenges: IDRC's ninth annual public meeting ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2018-01-02

    Jan 2, 2018 ... Lebel told the audience about a project he had visited recently in India that is introducing double-fortified salt, which contains both iodine and iron. Salt fortified with iodine nearly eradicated iodine-deficiency. Now, researchers in Canada and India are achieving a breakthrough with double-fortified salt that ...

  15. Animals in nuclear research: where ethics and expediency meet

    International Nuclear Information System (INIS)

    Newton, P.J.F.

    1988-01-01

    The Australian Nuclear Science and Technology Organisation (ANSTO) has a direct involvement in nuclear medicine, microbiological and environmental studies which utilise animals in the research work. The opposition to experiments on animals is briefly discussed. The Australia codes of practice for the care and use of animals for experimental purposes are outlined

  16. Silicon Valley Meets Biomedical Research in the Chan Zuckerberg Initiative.

    Science.gov (United States)

    Crow, Diana

    2017-05-18

    The Chan Zuckerberg Initiative, the philanthropy launched by Facebook CEO Mark Zuckerberg and his wife Priscilla Chan, drew attention with its stated goal of helping to "cure, manage, or treat all diseases" by the end of the century. They intend to do it through funding basic research and addressing gaps in biomedical technology. Copyright © 2017. Published by Elsevier Inc.

  17. Meeting

    Indian Academy of Sciences (India)

    Art" by Shri K K Chakravarty and on "Molecular mechanisms of transmembrane signalling" by. Prof. J Ramachandran ... software. B Basu, T ata Research Development and Design. Centre, Pune - Thermal science and engineering. S K Chakrabarti, Tata Institute of Fundamental. Research, Bombay - Theoretical astrophysics.

  18. Meeting

    Indian Academy of Sciences (India)

    1986-11-07

    Nov 7, 1986 ... The symposium was cosponsored by the. Ihdian Institute of 'Science, University Grants. Commission, Department of Science and. Technology, Defence Metallurgical Research. Laboratory, Indian Space Research. Organisation, Solid State Physics Laboratory,. Co.mmittee on Science and Technology in.

  19. Mapping Future Research in Disabilities--Research Initiatives in Intellectual Disabilities in India: Report of a National Interdisciplinary Meeting

    Science.gov (United States)

    Cohen, Libby; Brown, Roy I.

    2012-01-01

    A meeting organized under the auspices of the International Association for the Scientific Study of Intellectual Disabilities (IASSID) Academy on Education, Teaching and Research was held in March 2011 at the India International Centre in New Delhi, India, with the explicit purpose of helping establish a road map for future research in…

  20. The Ninth Annual American Association for Cancer Research International Conference on Frontiers in Cancer Prevention Research

    Science.gov (United States)

    Xu, Li; Wang, Sophia S.; Healey, Megan A.; Faupel-Badger, Jessica M.; Wilken, Jason A.; Battaglia, Tracy; Szabo, Eva; Mao, Jenny T.; Bergan, Raymond C.

    2016-01-01

    The Ninth Annual AACR Frontiers in Cancer Prevention Research conference was held in Philadelphia in November 7–10, 2010. Its thematic focus was “Prevention: From Basic Science to Public Health Benefit.” Telomere plasticity, the microenvironment, inflammation, transformation to the metastatic phenotype, and pathways to obesity were highlighted as important elements of carcinogenesis amenable to intervention. The integration of information from novel technologies related to physical biology, molecular and genetic profiles, and imaging along with behavioral and clinical parameters have advanced risk stratification and early detection. Cancer prevention represents a powerful testing ground for the development of individually tailored intervention and for increasing the efficiency of drug discovery. Advances in clinical trials relate to more efficient design strategies, have shown first-in-human targeting capabilities, and have developed powerful strategies to overcome accrual barriers. Tailored intervention strategies now show high efficacy on large cohorts across several cancer types. These successes are expected to increase. PMID:21464034

  1. Technology meets research 60 years of CERN technology : selected highlights

    CERN Document Server

    Taylor, Thomas; Treille, Daniel; Wenninger, Horst

    2017-01-01

    "Big" science and advanced technology are known to cross-fertilize. This book emphasizes the interplay between particle physics and technology at CERN that has led to breakthroughs in both research and technology over the laboratory's first 60 years. The innovations, often the work of individuals or by small teams, are illustrated with highlights describing selected technologies from the domains of accelerators and detectors. The book also presents the framework and conditions prevailing at CERN that enabled spectacular advances in technology and contributed to propel the European organization into the league of leading research laboratories in the world. While the book is specifically aimed at providing information for the technically interested general public, more expert readers may also appreciate the broad variety of subjects presented. Ample references are given for those who wish to further explore a given topic.

  2. X ray imaging microscope for cancer research

    Science.gov (United States)

    Hoover, Richard B.; Shealy, David L.; Brinkley, B. R.; Baker, Phillip C.; Barbee, Troy W., Jr.; Walker, Arthur B. C., Jr.

    1991-01-01

    The NASA technology employed during the Stanford MSFC LLNL Rocket X Ray Spectroheliograph flight established that doubly reflecting, normal incidence multilayer optics can be designed, fabricated, and used for high resolution x ray imaging of the Sun. Technology developed as part of the MSFC X Ray Microscope program, showed that high quality, high resolution multilayer x ray imaging microscopes are feasible. Using technology developed at Stanford University and at the DOE Lawrence Livermore National Laboratory (LLNL), Troy W. Barbee, Jr. has fabricated multilayer coatings with near theoretical reflectivities and perfect bandpass matching for a new rocket borne solar observatory, the Multi-Spectral Solar Telescope Array (MSSTA). Advanced Flow Polishing has provided multilayer mirror substrates with sub-angstrom (rms) smoothnesss for the astronomical x ray telescopes and x ray microscopes. The combination of these important technological advancements has paved the way for the development of a Water Window Imaging X Ray Microscope for cancer research.

  3. Differential network analysis in human cancer research.

    Science.gov (United States)

    Gill, Ryan; Datta, Somnath; Datta, Susmita

    2014-01-01

    A complex disease like cancer is hardly caused by one gene or one protein singly. It is usually caused by the perturbation of the network formed by several genes or proteins. In the last decade several research teams have attempted to construct interaction maps of genes and proteins either experimentally or reverse engineer interaction maps using computational techniques. These networks were usually created under a certain condition such as an environmental condition, a particular disease, or a specific tissue type. Lately, however, there has been greater emphasis on finding the differential structure of the existing network topology under a novel condition or disease status to elucidate the perturbation in a biological system. In this review/tutorial article we briefly mention some of the research done in this area; we mainly illustrate the computational/statistical methods developed by our team in recent years for differential network analysis using publicly available gene expression data collected from a well known cancer study. This data includes a group of patients with acute lymphoblastic leukemia and a group with acute myeloid leukemia. In particular, we describe the statistical tests to detect the change in the network topology based on connectivity scores which measure the association or interaction between pairs of genes. The tests under various scores are applied to this data set to perform a differential network analysis on gene expression for human leukemia. We believe that, in the future, differential network analysis will be a standard way to view the changes in gene expression and protein expression data globally and these types of tests could be useful in analyzing the complex differential signatures.

  4. Programmer Analyst | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Advanced Biomedical Computing Center (ABCC) provides technology development, scientific consultation, collaboration, data analysis and training to the National Cancer Institute (NCI) and National Institutes of Health (NIH) scientists and staff. The Core Infrastructure and Systems Biology (CISB) group in ABCC strives to streamline and provide innovative solutions for the NCI/NIH community to access and use biological information collected across different sources and formats. Integrating diverse data sources to enable disease agnostic access and analysis, variant impact annotation, identifier conversions across species, and merging clinical and research data enables translation from basic to the goal of precision medicine. CISB is looking for an experienced analyst to support the database and application management efforts at the NCI’s Molecular Targets Program (MTP). KEY ROLES/RESPONSIBILITIES Provide data management and analysis support Maintain scientific applications and databases on single-user personal computer through the multi-user, multi-processor large memory mainframe Communicate with the experts in the MTP, gather requirements and provide support Provide training to researchers on a variety of platforms and applications Evaluate and develop methodologies to allow utilization of new software tools and generate the information required by MTP researchers Determine methods and procedures on new assignments Document approaches and mechanisms clearly and comprehensively

  5. A Comprehensive Infrastructure for Big Data in Cancer Research: Accelerating Cancer Research and Precision Medicine

    Directory of Open Access Journals (Sweden)

    Izumi V. Hinkson

    2017-09-01

    Full Text Available Advancements in next-generation sequencing and other -omics technologies are accelerating the detailed molecular characterization of individual patient tumors, and driving the evolution of precision medicine. Cancer is no longer considered a single disease, but rather, a diverse array of diseases wherein each patient has a unique collection of germline variants and somatic mutations. Molecular profiling of patient-derived samples has led to a data explosion that could help us understand the contributions of environment and germline to risk, therapeutic response, and outcome. To maximize the value of these data, an interdisciplinary approach is paramount. The National Cancer Institute (NCI has initiated multiple projects to characterize tumor samples using multi-omic approaches. These projects harness the expertise of clinicians, biologists, computer scientists, and software engineers to investigate cancer biology and therapeutic response in multidisciplinary teams. Petabytes of cancer genomic, transcriptomic, epigenomic, proteomic, and imaging data have been generated by these projects. To address the data analysis challenges associated with these large datasets, the NCI has sponsored the development of the Genomic Data Commons (GDC and three Cloud Resources. The GDC ensures data and metadata quality, ingests and harmonizes genomic data, and securely redistributes the data. During its pilot phase, the Cloud Resources tested multiple cloud-based approaches for enhancing data access, collaboration, computational scalability, resource democratization, and reproducibility. These NCI-led efforts are continuously being refined to better support open data practices and precision oncology, and to serve as building blocks of the NCI Cancer Research Data Commons.

  6. Cancer fear and fatalism: how African American participants construct the role of research subject in relation to clinical cancer research.

    Science.gov (United States)

    Somayaji, Darryl; Cloyes, Kristin Gates

    2015-01-01

    Lack of African American participation in cancer clinical trials has been identified as a critical problem. Historical interactions related to race, identity, and power may contribute to continued inequity in healthcare and research participation. The aim of this study was to explore the perceptions of African Americans regarding cancer and research and how these perceptions shape their beliefs about participating as cancer research subjects. Three African American focus groups were conducted including people who had never participated in cancer research, those who had, and those who were asked but refused (n = 16). Discussion focused on their perceptions of cancer research and actual or potential participation as research subjects. Data were coded using both structured and inductive coding methods. Fear and fatalism emerged in relation to research, race, power, and identity and were related to larger historical and social issues rather than only individual thoughts or feelings. Participants described fears of the unknown, death, mistrust, conspiracy, and discrimination together with positive/negative tensions between self, family, and community responsibilities. Complex identities linked perceptions of cancer and cancer research with broader historical and cultural issues. Fear, fatalism, and current and historical relationships influence how people perceive themselves as research subjects and may influence their decisions to participate in cancer research. Acknowledging how complex factors including race and racism contribute to health disparities may give nurses and other healthcare providers a better appreciation of how historical, social, and cultural dynamics at individual, community, and organizational levels influence access to and participation in cancer research.

  7. Nurse Practitioner/Physician Assistant | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  8. Meeting report: Global vaccine and immunization research forum.

    Science.gov (United States)

    Ford, Andrew Q; Touchette, Nancy; Fenton Hall, B; Hwang, Angela; Hombach, Joachim

    2018-02-08

    Building on the success of the first Global Vaccine and Immunization Research Forum (GVIRF), the World Health Organization, the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health in the United States of America, and the Bill & Melinda Gates Foundation convened the second GVIRF in March 2016. Leading scientists, vaccine developers, and public health officials from around the world discussed scientific advances and innovative technologies to design and deliver vaccines as well as novel tools and approaches to increase the uptake of vaccines throughout the world. This report summarizes the discussions and conclusions from the forum participants. Copyright © 2018.

  9. Partnering Research Involving Mentoring and Education (PRIME) in Prostate Cancer

    National Research Council Canada - National Science Library

    Price, Marva M

    2008-01-01

    Partnering Research Involving Mentoring and Education in Prostate Cancer (PRIME) was a partnership between two nursing schools, Duke University School of Nursing and North Carolina Central University (NCCU...

  10. Partnering Research Involving Mentoring and Education (PRIME) in Prostate Cancer

    National Research Council Canada - National Science Library

    Price, Marva M

    2007-01-01

    Partnering Research Involving Mentoring and Education in Prostate Cancer (PRIME) is a partnership between two nursing schools, Duke University School of Nursing and North Carolina Central University (NCCU...

  11. Partnering Research Involving Mentoring and Education (PRIME) in Prostate Cancer

    National Research Council Canada - National Science Library

    Price, Marva M

    2006-01-01

    Partnering Research Involving Mentoring and Education in Prostate Cancer (PRIME) is a partnership between two nursing schools, Duke University School of Nursing and North Carolina Central University (NCCU...

  12. Canine cancer patients are included in translational research

    DEFF Research Database (Denmark)

    Børresen, Betina; Clausen, Malene Martini; Hansen, Anders Elias

    2014-01-01

    Cancer bearing dogs represent a unique clinical cancer model with a direct potential for accelerating translation into human patients. A research collaboration between the veterinary and human medical facilities at Copenhagen University and Rigshospitalet has taken offset in this. Canine cancer...

  13. Summary of the 2016 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

    Science.gov (United States)

    Boule, Lisbeth A; Ju, Cynthia; Agudelo, Marisela; Parira, Tiyash; Cannon, Abigail; Davis, Booker; Eby, Jonathan; Cresci, Gail; Samuelson, Derrick R; Shukla, Pradeep; Alrefai, Waddah A; Sureshchandra, Suhas; Pandey, Subhash C; Schnabl, Bernd; Curtis, Brenda J; Wyatt, Todd A; Choudhry, Mashkoor A; Kovacs, Elizabeth J

    2018-02-01

    On November 18, 2016 the 21st annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at the Center for Translational Research and Education at Loyola University Chicago's Health Sciences Campus in Maywood, IL. The 2016 meeting focused broadly on alcohol and inflammation, epigenetics, and the microbiome. The four plenary sessions of the meeting were Alcohol, Inflammation, and Immunity; Alcohol and Epigenetics; Alcohol, Transcriptional Regulation, and Epigenetics; and Alcohol, Intestinal Mucosa, and the Gut Microbiome. Presentations in all sessions of the meeting explored putative underlying causes for chronic diseases and mortality associated with alcohol consumption, shedding light on future work and potential therapeutic targets to alleviate the negative effects of alcohol misuse. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Proceedings of the 2nd specialist research meeting on the electromagnetic isotope separators and their applications

    International Nuclear Information System (INIS)

    Fujioka, Manabu; Kawase, Yoichi; Okano, Kotoyuki

    1992-07-01

    The EMIS-12 International Conference was held at Sendai in September, 1991 for the first time in Japan. It offered a nice opportunity to appeal a great progress in our country on the related fields and many interesting subjects were discussed. The second research meeting on Electromagnetic Isotope Separators and Their Applications was held at Kumatori on March 18 and 19, 1992, six months after the EMIS-12 Conference. Many interesting results obtained by using ISOLs were reported as in the previous meeting. In the present meeting, the measuring methods and the improved instruments were reported and discussed, which are fundamental for application of isotope separation methods to the interdisciplinary research fields. These valuable contributions to the meeting are involved in this Proceedings. (J.P.N.)

  15. Art meets science: The Cosmopolitan Chicken Research Project.

    Science.gov (United States)

    Stinckens, A; Vereijken, A; Ons, E; Konings, P; Van As, P; Cuppens, H; Moreau, Y; Sakai, R; Aerts, J; Goddeeris, B; Buys, N; Vanmechelen, K; Cassiman, J J

    2015-01-01

    The Cosmopolitan Chicken Project is an artistic undertaking of renowned artist Koen Vanmechelen. In this project, the artist interbreeds domestic chickens from different countries aiming at the creation of a true Cosmopolitan Chicken as a symbol for global diversity. The unifying theme is the chicken and the egg, symbols that link scientific, political, philosophical and ethical issues. The Cosmopolitan Chicken Research Project is the scientific component of this artwork. Based on state of the art genomic techniques, the project studies the effect of the crossing of chickens on the genetic diversity. Also, this research is potentially applicable to the human population. The setup of the CC®P is quite different from traditional breeding experiments: starting from the crossbreed of two purebred chickens (Mechelse Koekoek x Poule de Bresse), every generation is crossed with a few animals from another breed. For 26 of these purebred and crossbred populations, genetic diversity was measured (1) under the assumption that populations were sufficiently large to maintain all informative SNP within a generation and (2) under the circumstances of the CCP breeding experiment. Under the first assumption, a steady increase in genetic diversity was witnessed over the consecutive generations, thus indeed indicating the creation of a "Cosmopolitan Chicken Genome". However, under the conditions of the CCP, which reflects the reality within the human population, diversity is seen to fluctuate within given boundaries instead of steadily increasing. A reflection on this might be that this is because, in humans, an evolutionary optimum in genetic diversity is reached. Key words.

  16. Summary report of first research coordination meeting on Minor Actinide Nuclear Reaction Data (MANREAD)

    International Nuclear Information System (INIS)

    Kaeppeler, F.; Mengoni, A.

    2008-09-01

    The first Research Co-ordination Meeting of the MANREAD (Minor Actinides Neutron Reaction Data) was held at the IAEA Headquarters in Vienna from 19 to 23 November 2007. A summary of the discussion which took place at the meeting is reported here. In addition, a task assignment list of the experimental data assessment activities was agreed, and is provided together with the plan for future CRP activities. (author)

  17. Third research coordination meeting on reference database for neutron activation analysis. Summary report

    International Nuclear Information System (INIS)

    Kellett, M.A.

    2009-12-01

    The third meeting of the Co-ordinated Research Project on 'Reference Database for Neutron Activation Analysis' was held at the IAEA, Vienna from 17-19 November 2008. A summary of presentations made by participants is given, reports on specific tasks and subsequent discussions. With the aim of finalising the work of this CRP and in order to meet initial objectives, outputs were discussed and detailed task assignments agreed upon. (author)

  18. Sixth research coordination meeting on the measurement and evaluation of transactinium isotope nuclear data

    International Nuclear Information System (INIS)

    Lorenz, A.

    1983-11-01

    Proceedings of the sixth meeting of the participants in the IAEA Coordinated Research Programme to measure and evaluate the required nuclear decay data of heavy element radionuclides, convened by the IAEA Nuclear Data Section on 21-24 June 1983 at Idaho Falls, USA. The meeting participants reviewed the data requirements, updated and extended the recommended list of half-lives, and continued to review the status of alpha and gamma radiation spectra emitted in the decay of transactinium isotopes

  19. Report on the inaugural meeting of the international consortium on hallucination research : a clinical and research update and 16 consensus-set goals for future research

    NARCIS (Netherlands)

    Waters, F.; Aleman, A.; Fernyhough, C.; Allen, P.

    This article presents a report on the first meeting of the International Consortium on Hallucination Research, which took place on September 13-14, 2011 at the Institute of Psychiatry, London. The first day of the meeting served to reflect on the current state of knowledge regarding auditory

  20. The eighth Asia cancer forum: seeking to advance the outcomes of the UN summit: 'global health as the key to a new paradigm in cancer research'.

    Science.gov (United States)

    Kawahara, Norie; Akaza, Hideyuki; Roh, Jae Kyung; Shibuya, Kenji; Inoue, Hajime; Takemi, Keizo; Nozaki, Shinjiro; Kawakami, Koji; Iwasaki, Masaru

    2012-12-01

    To date, the Asia Cancer Forum has focused its efforts on creating a common concept for collaborative efforts in international cancer research with a focus on Asia, where cancer incidence is rising dramatically, and also sharing information and knowledge among cancer specialists about the importance of cancer as a global health agenda issue. The Eighth Asia Cancer Forum was held following the historic outcome of the High-level Meeting of the United Nations General Assembly on the Prevention and Control of Non-communicable Diseases held in New York in September 2011, at which cancer was duly recognized as a global health agenda issue. Despite this significant development, however, the issue of cancer, one of the most intractable of all non-communicable diseases, still faces a variety of challenges if it is to be addressed on the global level. The Eighth Asia Cancer Forum sought to address these various issues, seeking ways to capitalize on the outcomes of the UN Meeting and take global collaborative studies and alliances in the field of cancer further. It was recognized that one of the main challenges for the Asia Cancer Forum is to formulate a proposal that demonstrates how middle-income countries can provide a good level of care using only their own limited medical resources. Given that the Asia Cancer Forum is one of the organizations that can provide assistance in working to further boost awareness about cancer research and the situation relating to cancer in Asian countries, discussion also focused on how to concretize activities in the future.

  1. Do patients discussed at a lung cancer multidisciplinary team meeting receive guideline-recommended treatment?

    Science.gov (United States)

    Boxer, Miriam M; Duggan, Kirsten J; Descallar, Joseph; Vinod, Shalini K

    2016-03-01

    Clinical guidelines provide evidence-based management recommendations to guide practice. This study aimed to evaluate whether patients discussed at a lung cancer multidisciplinary team meeting received guideline-recommended treatment and determine reasons for not receiving guideline-recommended treatment. All new lung cancer patients discussed at the Liverpool/Macarthur lung cancer multidisciplinary team meeting between 1 December 2005 and 31 December 2010 were included. Guideline-recommended treatment was assigned according to pathology, stage and ECOG (Eastern Co-operative Oncology Group) performance status as per the 2004 Australian Lung Cancer Guidelines. This was compared with actual treatment received to determine adherence to guidelines. For those patients who did not receive guideline-recommended treatment, the medical record was reviewed to determine the reason(s) for this. Survival was compared between those who did and did not receive guideline-recommended treatment. 808 new patients were discussed at the multidisciplinary team meeting. Guideline-recommended treatment could not be assigned in 2% of patients due to missing data. 435 patients (54%) received guideline-recommended treatment, and 356 (44%) did not. The most common reasons for not receiving guideline-recommended treatment were a decline in ECOG performance status (24%), large tumor volume precluding radical radiotherapy (17%), comorbidities (15%) and patient preference (13%). Patients less than 70 years who received guideline-recommended treatment had improved survival compared with those who did not. A significant proportion of lung cancer patients did not receive guideline-recommended treatment due to legitimate reasons. Alternative guidelines are needed for patients not suitable for current best practice. Treatment according to guidelines was a predictor for survival. © 2015 Wiley Publishing Asia Pty Ltd.

  2. A Training Program in Breast Cancer Research Using NMR Techniques

    Science.gov (United States)

    2006-07-01

    mortality. Breast cancer can exist not only in the form of masses, but also in the forms of microcalcifications , asymmetric density, and architectural...treatment of breast cancer calls for early detection of cancerous lesions (e.g., clustered microcalcifications and masses associated with malignant...DAMD17-00-1-0291 TITLE: A Training Program in Breast Cancer Research Using NMR Techniques PRINCIPAL INVESTIGATOR: Paul C. Wang, Ph.D

  3. Major clinical research advances in gynecologic cancer in 2014

    OpenAIRE

    Suh, Dong Hoon; Lee, Kyung-Hun; Kim, Kidong; Kang, Sokbom; Kim, Jae-Weon

    2015-01-01

    In 2014, 9 topics were selected as major advances in clinical research for gynecologic oncology: 2 each in cervical and corpus cancer, 4 in ovarian cancer, and 1 in breast cancer. For cervical cancer, several therapeutic agents showed viable antitumor clinical response in recurrent and metastatic disease: bevacizumab, cediranib, and immunotherapies including human papillomavirus (HPV)-tumor infiltrating lymphocytes and Z-100. The HPV test received FDA approval as the primary screening tool of...

  4. Meharry-Johns Hopkins Center for Prostate Cancer Research

    Science.gov (United States)

    2015-11-01

    questionnaire to assess their prostate cancer health seeking behavior. 15. SUBJECT TERMS Prostate cancer, Dietary risk factors, Lycopene, Genetic ... predisposition , African-Americans, Cancer research training, Quality of life, Community outreach, Recruiting study participants, Cell line inhibition...Institute (NCI) state cancer profiles, the mortality rate is almost three times that of CA men (73.9 per 100,000 AA / 25.6 per 100,000 C). Genetic and

  5. Ethical review from the inside: repertoires of evaluation in Research Ethics Committee meetings

    NARCIS (Netherlands)

    de Jong, Jean Philippe; van Zwieten, Myra C. B.; Willems, Dick L.

    2012-01-01

    Evaluating the practice of ethical review by Research Ethics Committees (REC) could help protect the interests of human participants and promote scientific progress. To facilitate such evaluations, we conducted an ethnographic study of how an REC reviews research proposals during its meetings. We

  6. 76 FR 5650 - Rehabilitation Research and Development Service Scientific Merit Review Board; Notice of Meeting

    Science.gov (United States)

    2011-02-01

    ... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Service Scientific Merit...-463 (Federal Advisory Committee Act) that a meeting of the Rehabilitation Research and Development Service Scientific Merit Review Board will be held February 23-25 and March 1-2, 2011, at the Doubletree...

  7. 77 FR 21622 - Rehabilitation Research and Development Service Scientific Merit Review Board; Notice of Meeting

    Science.gov (United States)

    2012-04-10

    ... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Service Scientific Merit...-463 (Federal Advisory Committee Act) that a meeting of the Rehabilitation Research and Development Service Scientific Merit Review Board will be held on April 20, 2012, 131 M Street NE., Washington, DC...

  8. 77 FR 42365 - Health Services Research and Development Service Scientific Merit Review Board, Notice of Meeting

    Science.gov (United States)

    2012-07-18

    ... DEPARTMENT OF VETERANS AFFAIRS Health Services Research and Development Service Scientific Merit...-463 (Federal Advisory Committee Act) that various subcommittees of the Health Services Research and Development Service Scientific Merit Review Board will meet on August 28-30, 2012, at the Boston Omni Parker...

  9. 75 FR 72872 - Rehabilitation Research and Development Service Scientific Merit Review Board; Notice of Meeting

    Science.gov (United States)

    2010-11-26

    ... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Service Scientific Merit...-463 (Federal Advisory Committee Act) that a meeting of the Rehabilitation Research and Development Service Scientific Merit Review Board will be held on December 13-14, 2010, at the Hilton Alexandria Old...

  10. 78 FR 50144 - Rehabilitation Research and Development Service Scientific Merit Review Board; Notice of Meetings

    Science.gov (United States)

    2013-08-16

    ... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Service Scientific Merit... Advisory Committee Act, 5 U.S.C. App. 2, that the subcommittees of the Rehabilitation Research and Development Service Scientific Merit Review Board will meet from 8 a.m. to 5 p.m. on the dates indicated below...

  11. 76 FR 42167 - Rehabilitation Research and Development Service Scientific Merit Review Board; Notice of Meeting

    Science.gov (United States)

    2011-07-18

    ... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Service Scientific Merit...-463 (Federal Advisory Committee Act) that a meeting of the Rehabilitation Research and Development Service Scientific Merit Review Board will be held August 9-11 and 16-18, 2011, at the Sheraton Crystal...

  12. 78 FR 9455 - Rehabilitation Research and Development Service Scientific Merit Review Board, Notice of Meeting

    Science.gov (United States)

    2013-02-08

    ... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Service Scientific Merit... Advisory Committee Act, 5 U.S.C. App. 2, that the subcommittees of the Rehabilitation Research and Development Service Scientific Merit Review Board will meet from 8 a.m. to 5 p.m. on the dates indicated below...

  13. 77 FR 8330 - Health Services Research and Development Service Scientific Merit Review Board; Notice of Meeting

    Science.gov (United States)

    2012-02-14

    ... DEPARTMENT OF VETERANS AFFAIRS Health Services Research and Development Service Scientific Merit...-463 (Federal Advisory Committee Act) that various subcommittees of the Health Services Research and Development Service Scientific Merit Review Board will meet on March 6-8, 2012, at the Hilton New Orleans...

  14. 34 CFR 350.33 - What cooperation requirements must a Rehabilitation Engineering Research Center meet?

    Science.gov (United States)

    2010-07-01

    ... Engineering Research Centers Does the Secretary Assist? § 350.33 What cooperation requirements must a... 34 Education 2 2010-07-01 2010-07-01 false What cooperation requirements must a Rehabilitation Engineering Research Center meet? 350.33 Section 350.33 Education Regulations of the Offices of the Department...

  15. 77 FR 57569 - Science Advisory Board to the National Center for Toxicological Research; Notice of Meeting

    Science.gov (United States)

    2012-09-18

    ...] Science Advisory Board to the National Center for Toxicological Research; Notice of Meeting AGENCY: Food... closed to the public. Name of Committee: Science Advisory Board (SAB) to the National Center for Toxicological Research (NCTR). General Function of the Committee: To provide advice and recommendations to the...

  16. 75 FR 57967 - Science Advisory Board to the National Center for Toxicological Research Notice of Meeting

    Science.gov (United States)

    2010-09-23

    ...] Science Advisory Board to the National Center for Toxicological Research Notice of Meeting AGENCY: Food... closed to the public. Name of Committee: Science Advisory Board (SAB) to the National Center for Toxicological Research (NCTR). General Function of the Committee: To provide advice and recommendations to the...

  17. 76 FR 64355 - Science Advisory Board to the National Center for Toxicological Research; Notice of Meeting

    Science.gov (United States)

    2011-10-18

    ... future research needs in the area of regulatory science for personalized nutrition. Following the public...] Science Advisory Board to the National Center for Toxicological Research; Notice of Meeting AGENCY: Food... closed to the public. Name of Committee: Science Advisory Board (SAB) to the National Center for...

  18. Visual Impairment/Intracranial Pressure Research Clinical Advisory Panel (RCAP) Meeting. [Summary Report

    Science.gov (United States)

    Villarreal, Jennifer

    2014-01-01

    The Visual Impairment/Intracranial Pressure (VIIP) Research and Clinical Advisory Panel convened on December 1, 2014 at the ISS Conference Facility in Houston. The panel members were provided updates to the current clinical cases and treatment plans along with the latest research activities (http://humanresearchroadmap.nasa.gov/Risks/?i=105) and preliminary study results. The following is a summary of this meeting.

  19. 77 FR 2304 - National Human Genome Research Institute; Notice of Meeting

    Science.gov (United States)

    2012-01-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome....S.C. 281(d)(4)), notice is hereby given that the National Human Genome Research Institute (NHGRI... meeting of the National Advisory Council for Human Genome Research. Background materials on the proposed...

  20. 75 FR 44800 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-07-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... for Human Genome Research. The meeting will be closed to the public in accordance with the provisions... Committee: National Advisory Council for Human Genome Research. Date: August 18, 2010. Time: 1 p.m. to 3 p.m...

  1. The Ninth Annual American Association for Cancer Research International Conference on Frontiers in Cancer Prevention Research

    OpenAIRE

    Xu, Li; Wang, Sophia S.; Healey, Megan A.; Faupel-Badger, Jessica M.; Wilken, Jason A.; Battaglia, Tracy; Szabo, Eva; Mao, Jenny T.; Bergan, Raymond C.

    2011-01-01

    The Ninth Annual AACR Frontiers in Cancer Prevention Research conference was held in Philadelphia in November 7–10, 2010. Its thematic focus was “Prevention: From Basic Science to Public Health Benefit.” Telomere plasticity, the microenvironment, inflammation, transformation to the metastatic phenotype, and pathways to obesity were highlighted as important elements of carcinogenesis amenable to intervention. The integration of information from novel technologies related to physical biology, m...

  2. Commercial products and services of research reactors. Proceedings of a technical meeting

    International Nuclear Information System (INIS)

    2013-07-01

    Although the number of operational research reactors is steadily decreasing, more than half of those that remain are greatly underutilized and, in most cases, underfunded. To continue to play a key role in the development of peaceful uses of nuclear technology, the remaining research reactors will need to provide useful products and services to private, national and regional customers, in some cases with adequate revenue generation for reliable, safe and secure facility management and operation. In the light of declining governmental financial support and the need for improved physical security and conversion to low enriched uranium (LEU) fuel, many research reactors have been challenged to generate income to offset increasing operational and maintenance costs. The renewed interest in nuclear power (and therefore in nuclear education and training), the global expansion of diagnostic and therapeutic nuclear medicine, and the extensive use of semiconductors in electronics and in other areas have created new opportunities for research reactors, prominent among them, markets for products and services in regions and countries without such facilities. It is clear that such initiatives towards greater self-reliance will need to address such aspects as market surveys, marketing and business plans, and cost of delivery services. It will also be important to better inform present and future potential end users of research reactor services of the capabilities and products that can be provided. This publication is a compilation of material from an IAEA technical meeting on “Commercial Products and Services of Research Reactors”, held in Vienna, Austria, from 28 June to 2 July 2010. The overall objective of the meeting was to exchange information on good practices and to provide concrete examples, in technical presentations and brainstorming discussions, to promote and facilitate the development of commercial applications of research reactors. The meeting also aimed to

  3. Researching experiences of cancer: the importance of methodology.

    Science.gov (United States)

    Entwistle, V; Tritter, J Q; Calnan, M

    2002-09-01

    This paper draws on contributions to and discussions at a recent MRC HSRC-sponsored workshop 'Researching users' experiences of health care: the case of cancer'. We focus on the methodological and ethical challenges that currently face researchers who use self-report methods to investigate experiences of cancer and cancer care. These challenges relate to: the theoretical and conceptual underpinnings of research; participation rates and participant profiles; data collection methods (the retrospective nature of accounts, description and measurement, and data collection as intervention); social desirability considerations; relationship considerations; the experiences of contributing to research; and the synthesis and presentation of findings. We suggest that methodological research to tackle these challenges should be integrated into substantive research projects to promote the development of a strong knowledge base about experiences of cancer and cancer care.

  4. Meeting the needs of cancer patients: is there a need for an organizational change?

    Science.gov (United States)

    Foà, Chiara; Mancini, Tiziana; Prandi, Rossella; Ghirardi, Linda; De Vincenzi, Franca; Cornelli, Maria Cristina; Copelli, Patrizia; Artioli, Giovanna

    2015-01-01

    As stated in the literature the most important needs of cancer patients are not adequately meet. Improving information, communication and education provided have not led to incisive changes in the organizational model of the oncology departments. The study contributes to this direction, by planning an "Integrated Operating Point" (I.O.P.) dedicated to cancer patients and their relatives in Italy. 42 Some professionals, patients and relatives were involved and 42 of them participated in focus group/or interviews. Results of thematic content analysis allow us to sketch out some key elements that I.O.P. should have in order to support cancer patients and their families. Integration of services, continuity of care, and cooperation between professionals involved are key elements that might qualify such organizational development.

  5. Cancer Control Research Training for Native Researchers: A Model for Development of Additional Native Researcher Training Programs

    Science.gov (United States)

    Becker, Thomas M.; Dunn, Esther; Tom-Orme, Lillian; Joe, Jennie

    2005-01-01

    Several social and biological scientists who have Native status are engaged in productive research careers, but the encouragement that has been offered to Native students to formulate career goals devoted to cancer etiology or cancer control in Native peoples has had limited success. Hence, the Native Researchers' Cancer Control Training Program…

  6. Summary of the 6th Annual Bladder Cancer Think Tank: new directions in urologic research.

    Science.gov (United States)

    Svatek, Robert S; Rosenberg, Jonathan E; Galsky, Matthew D; Lee, Cheryl T; Latini, David M; Bochner, Bernard H; Weizer, Alon Z; Apolo, Andrea B; Sridhar, Srikala S; Kamat, Ashish M; Hansel, Donna; Flaig, Thomas W; Smith, Norm D; Lotan, Yair

    2013-10-01

    The 6th Annual Bladder Cancer Think Tank brought together a multidisciplinary group of clinicians, researchers, and representatives from the National Cancer Institute and Industry in an effort to advance bladder cancer research efforts. This year's meeting comprised panel discussions and research involving 5 separate working groups, including the Survivorship, Clinical Trials, Standardization of Care, Data Mining, and Translational Science working groups. In this manuscript, the accomplishments and objectives of the working groups are summarized. Notable efforts include: (1) the development of a survivorship care plan for early and late-stage bladder cancer; (2) the development of consensus criteria for eligibility and endpoints for bladder cancer clinical trials; (3) an improved understanding of current practice patterns regarding the use of perioperative chemotherapy in an effort to standardize care; (4) creation of a comprehensive handbook to assist researchers with developing bladder cancer databases; and (5) identification of response to therapy of high-grade non muscle invasive disease through a collaborative exchange of expertise and resources. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. The global forum on bioethics in research meeting, "ethics of research in pregnancy": emerging consensus themes and outputs.

    Science.gov (United States)

    Hunt, Adrienne; Banner, Natalie; Littler, Katherine

    2017-12-14

    Research during pregnancy is affected by multiple ethical challenges which have not received sufficient international attention and consideration from the bioethics, clinical, and policymaking communities working together. Unresolved ethical questions about research in pregnancy have significant detrimental impacts on maternal and newborn health, in part because they inhibit an evidence base being developed on the efficacy and safety of medicines and health interventions for pregnant women. These problems are compounded in low- and middle-income country (LMIC) settings due to variability in regulatory provisions, the burden of maternal morbidity and mortality, and many social and cultural conventions that impact on pregnant women's ability to participate in research. Research in pregnancy was chosen as a topic for the 2016 Global Forum on Bioethics in Research (GFBR) meeting, and its timeliness was all the more apparent given the 2016 Zika outbreak, which has deeply affected the Latin American region. The meeting's emerging consensus themes and outputs epitomized the core aims of the GFBR-to give voice to LMIC perspectives as a priority in dialogue about global health research ethics and to promote collaboration. In this instance, the GFBR meeting catalyzed a strong, unified drive to push researchers and policymakers to include pregnant women in research by default: given the complex nature of the topic, this is a significant achievement in addressing an important question of social justice.

  8. Research progress in applying proteomics technology to explore early diagnosis biomarkers of breast cancer, lung cancer and ovarian cancer.

    Science.gov (United States)

    Luo, Lu; Dong, Li-You; Yan, Qi-Gui; Cao, San-Jie; Wen, Xin-Tian; Huang, Yong; Huang, Xiao-Bo; Wu, Rui; Ma, Xiao-Ping

    2014-01-01

    According to the China tumor registry 2013 annual report , breast cancer, lung cancer, and ovarian cancer are three common cancers in China nowadays, with high mortality due to the absence of early diagnosis technology. However, proteomics has been widespreadly implanted into every field of life science and medicine as an important part of post-genomics era research. The development of theory and technology in proteomics has provided new ideas and research fields for cancer research. Proteomics can be used not only for elucidating the mechanisms of carcinogenesis focussing on whole proteins of the tissue or cell, but also seeking the biomarkers for diagnosis and therapy of cancer. In this review, we introduce proteomics principles, covering current technology used in exploring early diagnosis biomarkers of breast cancer, lung cancer and ovarian cancer.

  9. Is concordance with World Cancer Research Fund/American Institute for Cancer Research guidelines for cancer prevention related to subsequent risk of cancer? Results from the EPIC study.

    Science.gov (United States)

    Romaguera, Dora; Vergnaud, Anne-Claire; Peeters, Petra H; van Gils, Carla H; Chan, Doris S M; Ferrari, Pietro; Romieu, Isabelle; Jenab, Mazda; Slimani, Nadia; Clavel-Chapelon, Françoise; Fagherazzi, Guy; Perquier, Florence; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; von Rüsten, Anne; Tjønneland, Anne; Olsen, Anja; Dahm, Christina C; Overvad, Kim; Quirós, José Ramón; Gonzalez, Carlos A; Sánchez, María José; Navarro, Carmen; Barricarte, Aurelio; Dorronsoro, Miren; Khaw, Kay-Tee; Wareham, Nicholas J; Crowe, Francesca L; Key, Timothy J; Trichopoulou, Antonia; Lagiou, Pagona; Bamia, Christina; Masala, Giovanna; Vineis, Paolo; Tumino, Rosario; Sieri, Sabina; Panico, Salvatore; May, Anne M; Bueno-de-Mesquita, H Bas; Büchner, Frederike L; Wirfält, Elisabet; Manjer, Jonas; Johansson, Ingegerd; Hallmans, Göran; Skeie, Guri; Benjaminsen Borch, Kristin; Parr, Christine L; Riboli, Elio; Norat, Teresa

    2012-07-01

    In 2007 the World Cancer Research Fund (WCRF) and the American Institute of Cancer Research (AICR) issued 8 recommendations (plus 2 special recommendations) on diet, physical activity, and weight management for cancer prevention on the basis of the most comprehensive collection of available evidence. We aimed to investigate whether concordance with the WCRF/AICR recommendations was related to cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The present study included 386,355 EPIC participants from 9 European countries. At recruitment, dietary, anthropometric, and lifestyle information was collected. A score was constructed based on the WCRF/AICR recommendations on weight management, physical activity, foods and drinks that promote weight gain, plant foods, animal foods, alcoholic drinks, and breastfeeding for women; the score range was 0-6 for men and 0-7 for women. Higher scores indicated greater concordance with WCRF/AICR recommendations. The association between the score and cancer risk was estimated by using multivariable Cox regression models. Concordance with the score was significantly associated with decreased risk of cancer. A 1-point increment in the score was associated with a risk reduction of 5% (95% CI: 3%, 7%) for total cancer, 12% (95% CI: 9%, 16%) for colorectal cancer, and 16% (95% CI: 9%, 22%) for stomach cancer. Significant associations were also observed for cancers of the breast, endometrium, lung, kidney, upper aerodigestive tract, liver, and esophagus but not for prostate, ovarian, pancreatic, and bladder cancers. Adherence to the WCRF/AICR recommendations for cancer prevention may lower the risk of developing most types of cancer.

  10. Lung cancer multidisciplinary team meetings: a survey of participants at a national conference

    International Nuclear Information System (INIS)

    Bydder, S.; Hasani, A.; Broderick, C.; Semmens, J.

    2008-01-01

    Full text: Multidisciplinary meetings (MDMs) are a useful aid for the development of comprehensive treatment plans for cancer patients. However, little is known about the requirements for effective MDM function. Attendees at a national lung cancer conference who participated at least weekly in lung cancer MDMs were surveyed. The survey addressed the attendees' perceptions regarding the aims of MDMs, and for their own institutional MDMs, the importance and need for improvement for each of: (i) the attendance of nine discipline groups; and (ii) 15 aspects related to MDM function derived from the literature. The survey also asked participants if MDMs met their needs. There was a general agreement on the aims of the meetings. There was also an agreement on the importance of various groups' attendance and each of the examined aspects of MDMs. However, many respondents reported their meetings required moderate or substantial improvements in one or more areas. More than 20% of the respondents indicated improvement was required for the attendance of three discipline groups (palliative care physicians, pathologists and cardiothoracic surgeons) and 10 of the 15 examined aspects (more than half in the case of computerised databases). Only 9% of the respondents reported that none of the features surveyed needed either moderate or substantial improvement. MDMs met the needs of 79% of the respondents. We found general agreement on the aims of the meetings, the importance of various groups' attendance at MDMs and each of the examined aspects of MDMs. However, moderate or substantial improvements were thought to be required by many respondents. The performance of individual institutions' MDMs and the resources they have available to achieve their aims should be assessed and periodically reviewed. The survey applied here may provide a framework for MDM members to do this.

  11. Cancer Research UK | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cancer Research UK. Cancer Research UK. IDRC to populate at a later date. https://www.cancerresearchuk.org/. Nous finançons des chercheurs qui inspirent des changements mondiaux. Abonnez-vous · Carrières · Communiquez avec nous · Désabonnez-vous · Plan du site. Suivez-nous; Facebook · Twitter · Youtube ...

  12. IDRC and Cancer Research UK partner on innovative new tobacco ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-10-18

    Oct 18, 2017 ... IDRC and Cancer Research UK are pleased to announce the launch of a new five-year initiative aimed at preventing tobacco-related diseases and promoting ... Cancer Research UK's international tobacco control program seeks to accelerate the implementation of the Framework Convention on Tobacco ...

  13. Proceedings of the meeting for coordinating precision machining of optics research and requirements

    International Nuclear Information System (INIS)

    Saito, T.T.

    1975-12-01

    The meeting for ''Coordinating Precision Machining of Optics Research and Requirements'' on September 18, 1975, was sponsored by the Air Force Weapons Laboratory at Kirtland AFB, NM. These proceedings contain an introduction to the meeting including a brief description of the participants and the objectives. The developments and capabilities of Union Carbide Y-12 plant are described in detail. A short summary of the new Moore no. 5 machine at Bendix, Kansas City, Mo. is included as well as a description of using light scattering for roughness characterization at Rockwell International, Rocky Flats, Colorado. The executive summary of the meeting mentions some of the discussions that also followed. Important conclusions of the meeting were that a 5 y lead time is required to obtain a machine and acquire the necessary skills for precision machining, and that demands for diamond turning optics will be increasing

  14. Proceedings of the 1988 International Meeting on Reduced Enrichment for Research and Test Reactors

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-01

    The international effort to develop and implement new research reactor fuels utilizing low-enriched uranium, instead of highly- enriched uranium, continues to make solid progress. This effort is the cornerstone of a widely shared policy aimed at reducing, and possibly eliminating, international traffic in highly-enriched uranium and the nuclear weapon proliferation concerns associated with this traffic. To foster direct communication and exchange of ideas among the specialists in this area, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at Argonne National Laboratory, sponsored this meeting as the eleventh of a series which began 1978. Individual papers presented at the meeting have been cataloged separately.

  15. Proceedings of the 1988 International Meeting on Reduced Enrichment for Research and Test Reactors

    International Nuclear Information System (INIS)

    1993-07-01

    The international effort to develop and implement new research reactor fuels utilizing low-enriched uranium, instead of highly- enriched uranium, continues to make solid progress. This effort is the cornerstone of a widely shared policy aimed at reducing, and possibly eliminating, international traffic in highly-enriched uranium and the nuclear weapon proliferation concerns associated with this traffic. To foster direct communication and exchange of ideas among the specialists in this area, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at Argonne National Laboratory, sponsored this meeting as the eleventh of a series which began 1978. Individual papers presented at the meeting have been cataloged separately

  16. The first Studsvik AB - JAEA meeting for cooperation in nuclear energy research and development

    International Nuclear Information System (INIS)

    Ishihara, Masahiro; Yanagihara, Satoshi; Karlsson, Mikael; Stenmark, Anders

    2009-01-01

    Based on the implemental agreement between the Studsvik AB and the Japan Atomic Energy Agency (JAEA) for cooperation in nuclear energy research and development, the first annual meeting was held at Oarai Research and Development Center, Japan Atomic Energy Agency. In this meeting, information exchange on two cooperation areas, 'Radioactive waste treatment technology including recycling of materials' and 'Technical developments for the neutron irradiation experiments in materials testing reactors', was carried out, and future plan in cooperation was discussed. This report describes contents of information exchange and discussions in two cooperation areas. (author)

  17. ENS RRFM 2005: 9th international topical meeting on research reactor fuel management. Transactions

    International Nuclear Information System (INIS)

    2005-01-01

    The ENS topical meeting on research reactor fuel management is an annual conference launched successfully in 1997. It has since then grown into well established international forum for the exchange and expertise on all significant aspects of the nuclear fuel cycle of research reactors. Oral presentations at this meeting were divided in the following four sessions: International Topics; Fuel Development, Qualification, Fabrication and Licensing; Reactor Operation, Fuel Safety and Core Conversion; Spent Fuel Management, Back-end Options, Transportation. The three poster sessions were devoted to fuel development, qualification, fabrication and licensing; reactor operation, fuel safety, core conversion, spent fuel; spent fuel management, fuel cycle back-end options, transportation

  18. II International Congress on small animals and JDC-VEPA I National Meeting of Research in Animal Science

    OpenAIRE

    Autores Varios

    2013-01-01

    SCIENTIFIC RESEARCH INSTITUTE - INICIENFACULTY OF AGRICULTURAL SCIENCES II International Congress on small animals and JDC-VEPA I National Meeting of Animal science research RESEARCH GROUPS INPANTA-CEAS-GREBIAL-IRABI II International Congress on small animals and JDC-VEPA I National Meeting of Research in Animal Science

  19. Next generation distributed computing for cancer research.

    Science.gov (United States)

    Agarwal, Pankaj; Owzar, Kouros

    2014-01-01

    Advances in next generation sequencing (NGS) and mass spectrometry (MS) technologies have provided many new opportunities and angles for extending the scope of translational cancer research while creating tremendous challenges in data management and analysis. The resulting informatics challenge is invariably not amenable to the use of traditional computing models. Recent advances in scalable computing and associated infrastructure, particularly distributed computing for Big Data, can provide solutions for addressing these challenges. In this review, the next generation of distributed computing technologies that can address these informatics problems is described from the perspective of three key components of a computational platform, namely computing, data storage and management, and networking. A broad overview of scalable computing is provided to set the context for a detailed description of Hadoop, a technology that is being rapidly adopted for large-scale distributed computing. A proof-of-concept Hadoop cluster, set up for performance benchmarking of NGS read alignment, is described as an example of how to work with Hadoop. Finally, Hadoop is compared with a number of other current technologies for distributed computing.

  20. Linking International Cancer Screening Efforts

    Science.gov (United States)

    Drs. Sudha Sivaram and Steve Taplin speak at the International Cancer Screening Network (ICSN) Meeting, which brings together individuals involved in cancer screening research and cancer screening programs from the ICSN’s member countries.

  1. Adherence to the World Cancer Research Fund/American Institute for Cancer Research recommendations and colorectal cancer risk.

    Science.gov (United States)

    Turati, Federica; Bravi, Francesca; Di Maso, Matteo; Bosetti, Cristina; Polesel, Jerry; Serraino, Diego; Dalmartello, Michela; Giacosa, Attilio; Montella, Maurizio; Tavani, Alessandra; Negri, Eva; La Vecchia, Carlo

    2017-11-01

    The World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) released in 2007 eight recommendations for cancer prevention on body fatness, diet and physical activity. Our aim is to evaluate the relation between adherence to these recommendations and colorectal cancer (CRC) risk. We pooled data from two Italian case-control studies including overall 2419 patients with CRC and 4723 controls. Adherence to the WCRF/AICR guidelines was summarised through a score incorporating seven of the WCRF/AICR recommendations, with higher scores indicating higher adherence to the guidelines. Odds ratios (ORs) of colorectal cancer were estimated using multiple logistic regression models. Higher adherence to the WCRF/AICR recommendations was associated with a significantly reduced CRC risk (OR 0.67, 95% confidence interval, CI, 0.56-0.80 for a score ≥5 versus cancer (OR 0.67). Inverse associations were observed with the diet-specific WCRF/AICR score (OR 0.71, 95% CI, 0.61-0.84 for ≥3.5 versus <2.5 points) and with specific recommendations on body fatness (OR 0.82, 95% CI, 0.70-0.97), physical activity (OR 0.86, 95% CI, 0.75-1.00), foods and drinks that promote weight gain (OR 0.70, 95% CI, 0.56-0.89), foods of plant origin (OR 0.56, 95% CI, 0.42-0.76), limiting alcohol (OR 0.87, 95% CI, 0.77-0.99) and salt intake (OR 0.63, 95% CI, 0.48-0.84). Our study indicated that adherence to the WCRF/AICR recommendations is inversely related to CRC risk. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Research Training Program in Breast Cancer

    Science.gov (United States)

    2001-07-01

    entry. Genes & Dev. 12: 456-461. Zhao, J., Kennedy, B.K., Lawrence, B.D., Barbie , D., Matera, A.G., Fletcher, J.A., and Harlow, E. 2000. NPAT links...Analysis of the NuRD subunits reveals a histone deacetylase core complex and a genetic studies of early breast cancer evolution . Breast Cancer Res

  3. Skin Cancer: NIH Research to Results

    Science.gov (United States)

    ... train a person's immune cells to attack the skin cancer cells. New melanoma drugs. The U.S. Food and Drug Administration recently ... immune system cells found in tumors could shrink skin cancer tumors and possibly prolong life. Melanoma increasing among children. Although rare, melanoma among children ...

  4. Adherence to the World Cancer Research Fund/American Institute for Cancer Research lifestyle recommendations in colorectal cancer survivors : Results of the PROFILES registry

    NARCIS (Netherlands)

    Winkels, Renate M; van Lee, Linde; Beijer, Sandra; Bours, Martijn J; van Duijnhoven, Fränzel J B; Geelen, Anouk; Hoedjes, M.; Mols, F.; de Vries, Jeanne; Weijenberg, Matty P; Kampman, Ellen

    2016-01-01

    We examined adherence to the eight The World Cancer Research Foundation/American Institute for Cancer Research (WCRF/AICR) recommendations on diet, physical activity, and body weight among colorectal cancer survivors, and whether adherence was associated with intention to eat healthy and with the

  5. Designing Trojan Horses | Center for Cancer Research

    Science.gov (United States)

    Waging battle against cancer cells without inflicting damage on normal tissue has long been a goal for cancer treatment. A new type of drug called immunotoxins may help make this goal a reality. Much like the Greeks used a wooden horse to get soldiers inside the gates of Troy, immunotoxins use clever genetic engineering to get a lethal toxin inside cancer cells. Each immunotoxin consists of two components an antibody and a toxin that are fused together. The custom-designed antibody acts as a homing signal, seeking out a specific target present on the surface of cancer cells. When the antibody binds its target, the whole immunotoxin is brought inside the cell. Unwittingly, the cancer cell has exposed itself to a powerful poison, a mistake that will likely condemn it to death.

  6. Learning from Cancer Precursors | Center for Cancer Research

    Science.gov (United States)

    Cancers that are preceded by distinct nonmalignant lesions provide an opportunity to study cancer progression and develop early detection and intervention strategies. Multiple myeloma—a cancer of the bone marrow that originates in a type of white blood cell called plasma cells—is consistently preceded by one of two nonmalignant precursor diseases: monoclonal gammopathy of undetermined significance (MGUS) or smoldering myeloma. Ola Landgren, M.D., Ph.D., and Adam Waxman, B.A., of the CCR Medical Oncology Branch recently published a case presentation and review in JAMA that discusses current understanding of myeloma precursor diseases and future opportunities for improving personalized management of patients with these conditions.

  7. Eliminating cancer stem cells: an interview with CCR’s Steven Hou | Center for Cancer Research

    Science.gov (United States)

    Steven Hou, Ph.D., senior investigator in the Basic Research Laboratory at the Center for Cancer Research describes his latest research that has uncovered potential ways to eliminate cancer stem cells and may offer hope to patients with reoccurring tumors.  Learn more...

  8. The John Milner Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

    Science.gov (United States)

    The Nutritional Science Research Group in the Division of Cancer Prevention at the National Cancer Institute, National Institutes of Health and the Department of Nutrition at the Clinical Center, National Institutes of Health, and the U.S. Department of Agriculture’s Beltsville Human Nutrition Research Center are offering a one-week educational opportunity in Nutrition and Cancer Prevention Research for individuals with a sustained commitment to nutrition and health promotion. |

  9. An ET-CURE pilot project supporting undergraduate training in cancer research, emerging technology, and health disparities.

    Science.gov (United States)

    Wilson, Danyell S; Fang, Bin; Dalton, William S; Meade, Cathy D; Koomen, John M

    2012-06-01

    The National Cancer Institute's Center to Reduce Cancer Health Disparities has created pilot training opportunities under the "Continuing Umbrella of Research Experiences" program that focus on emerging technologies. In this pilot project, an 18-month cancer biology research internship was reinforced with: instruction in an emerging technology (proteomics), a transition from the undergraduate laboratory to a research setting, education in cancer health disparities, and community outreach activities. A major goal was to provide underrepresented undergraduates with hands-on research experiences that are rarely encountered at the undergraduate level, including mentoring, research presentations, and participation in local and national meetings. These opportunities provided education and career development for the undergraduates, and they have given each student the opportunity to transition from learning to sharing their knowledge and from being mentored to mentoring others. Here, we present the concepts, curriculum, infrastructure, and challenges for this training program along with evaluations by both the students and their mentors.

  10. Physician Assistant/Sr. Nurse Practitioner | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  11. Challenges and opportunities in international molecular cancer prevention research: An ASPO Molecular Epidemiology and the Environment and International Cancer Prevention Interest Groups Report.

    Science.gov (United States)

    Epplein, Meira; Bostick, Roberd M; Mu, Lina; Ogino, Shuji; Braithwaite, Dejana; Kanetsky, Peter A

    2014-11-01

    The International Agency for Research on Cancer estimates that over half of the new cancer cases and almost two-thirds of the cancer deaths in 2012 occurred in low and middle income countries. To discuss the challenges and opportunities to reducing the burden of cancer worldwide, the Molecular Epidemiology and the Environment and the International Issues in Cancer Special Interest Groups joined forces to hold a session during the 38th Annual Meeting of the American Society of Preventive Oncology (March 2014, Arlington, Virginia). The session highlighted three topics of particular interest to molecular cancer prevention researchers working internationally, specifically: 1) biomarkers in cancer research; 2) environmental exposures and cancer; and 3) molecular pathological epidemiology. A major factor for successful collaboration illuminated during the discussion was the need for strong, committed, and reliable international partners. A key element of establishing such relationships is to thoroughly involve individual international collaborators in the development of the research question; engaged international collaborators are particularly motivated to champion and shepherd the project through all necessary steps, including issues relating to institutional review boards, political sensitivity, laboratory-based assays, and tumor subtyping. Also essential is allotting time for the building, maintaining, and investing in such relationships so that successful international collaborations may take root and bloom. While there are many challenges inherent to international molecular cancer research, the opportunities for furthering the science and prevention of cancer worldwide are great, particularly at this time of increasing cancer incidence and prevalence in low and middle income countries. ©2014 American Association for Cancer Research.

  12. The potential consequences for cancer care and cancer research of Brexit.

    Science.gov (United States)

    Selby, Peter; Lawler, Mark; Baird, Richard; Banks, Ian; Johnston, Patrick; Nurse, Paul

    2017-01-01

    Following the UK "Brexit" vote in June 2016, there are many uncertainties and risks for cancer research and cancer care in the UK. These are summarised and the importance of sustained engagement and influence from the cancer community on UK governments is emphasised.

  13. Scientists repurpose HPV vaccine technology to fight eye cancer | Center for Cancer Research

    Science.gov (United States)

    Uveal melanoma is a rare eye cancer that affects about 1,600 people in the United States. A study by scientists in the Center for Cancer Research and Aura Biosciences, Cambridge, Mass., published December 14, 2017, in Molecular Cancer Therapeutics, provides new hope for the early treatment of uveal melanoma. Read more…

  14. Bringing global cancer leaders together at the 4th Annual Symposium on Global Cancer Research

    Science.gov (United States)

    The Annual Symposium on Global Cancer Research held in April 2016 was developed with a special focus on innovative and low-cost technologies in global cancer control, and brought inspiring keynote speakers such as John Seffrin, Former CEO of the American Cancer Society, and Tom Bollyky, Senior Fellow for Global Health at the Council on Foreign Relations.

  15. 75 FR 65405 - Research Advisory Committee on Gulf War Veterans' Illnesses; Notice of Meeting

    Science.gov (United States)

    2010-10-22

    ... plans and research strategies relating to the health consequences of military service in the Southwest... inflammation, mitochondrial damage, and pain. There will also be updates of the VA Gulf War research program... toxicogenomics, cancer, and acupuncture as a potential treatment for ill Gulf War veterans. Additionally, there...

  16. Objectives | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The overall objective of CPTAC is to systematically identify proteins that derive from alterations in cancer genomes and related biological processes, in order to understand the molecular basis of cancer that is not fully elucidated or not possible through genomics and to accelerate the translation of molecular findings into the clinic.  This is to be achieved through enhancing our understanding of cancer genome biology by adding a complementary functional layer of protein biology (a “proteogenome” approach) that refines/prioritizes driver genes, enhances understanding of pathogenesis

  17. Major clinical research advances in gynecologic cancer in 2014.

    Science.gov (United States)

    Suh, Dong Hoon; Lee, Kyung Hun; Kim, Kidong; Kang, Sokbom; Kim, Jae Weon

    2015-04-01

    In 2014, 9 topics were selected as major advances in clinical research for gynecologic oncology: 2 each in cervical and corpus cancer, 4 in ovarian cancer, and 1 in breast cancer. For cervical cancer, several therapeutic agents showed viable antitumor clinical response in recurrent and metastatic disease: bevacizumab, cediranib, and immunotherapies including human papillomavirus (HPV)-tumor infiltrating lymphocytes and Z-100. The HPV test received FDA approval as the primary screening tool of cervical cancer in women aged 25 and older, based on the results of the ATHENA trial, which suggested that the HPV test was a more sensitive and efficient strategy for cervical cancer screening than methods based solely on cytology. For corpus cancers, results of a phase III Gynecologic Oncology Group (GOG) 249 study of early-stage endometrial cancer with high-intermediate risk factors are followed by the controversial topic of uterine power morcellation in minimally invasive gynecologic surgery. Promising results of phase II studies regarding the effectiveness of olaparib in various ovarian cancer settings are summarized. After a brief review of results from a phase III study on pazopanib maintenance therapy in advanced ovarian cancer, 2 outstanding 2014 ASCO presentations cover the topic of using molecular subtypes in predicting response to bevacizumab. A review of the use of opportunistic bilateral salpingectomy as an ovarian cancer preventive strategy in the general population is presented. Two remarkable studies that discussed the effectiveness of adjuvant ovarian suppression in premenopausal early breast cancer have been selected as the last topics covered in this review.

  18. IAEA technical committee meeting on research using small fusion devices (abstracts)

    International Nuclear Information System (INIS)

    1999-12-01

    The thirteenth IAEA technical committee meeting on research using small fusion devices are held in Chengdu, P. R. China on 18-20 Oct. , 1999. 41 articles are received and the content includes toroidal systems, helical systems, plasma focus, diagnostic systems, theory and modeling, improving confinement, numerical simulation, innovative concepts and others

  19. 77 FR 64816 - National Human Genome Research Institute; Notice of Meeting

    Science.gov (United States)

    2012-10-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome..., National Human Genome Research Institute. The meeting will be open to the public as indicated below, with... invasion of personal privacy. Name of Committee: Board of Scientific Counselors, National Human Genome...

  20. 76 FR 65204 - National Human Genome Research Institute; Notice of Meeting

    Science.gov (United States)

    2011-10-20

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome..., National Human Genome Research Institute. The meeting will be open to the public as indicated below, with... invasion of personal privacy. Name of Committee: Board of Scientific Counselors, National Human Genome...

  1. 75 FR 60467 - National Human Genome Research Institute; Notice of Meeting

    Science.gov (United States)

    2010-09-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome..., National Human Genome Research Institute. The meeting will be open to the public as indicated below, with... invasion of personal privacy. Name of Committee: Board of Scientific Counselors, National Human Genome...

  2. 78 FR 61362 - Advisory Council on Alzheimer's Research, Care, and Services; Meeting

    Science.gov (United States)

    2013-10-03

    ... welcome new members and discuss the timeline for the 2014 recommendations. The subcommittees will discuss... harness ``big data'' to address Alzheimer's research. DATES: The meeting will be held on October 28, 2013... welcome new members and discuss the timeline for the 2014 recommendations. The subcommittees will discuss...

  3. 75 FR 36695 - Solicitation for a Cooperative Agreement: Meetings of the Institutional Corrections Research...

    Science.gov (United States)

    2010-06-28

    ... performance standards, and incorporate data-driven approaches in their strategic planning and organizational... discussions and the meetings of other similar groups. One is the network's relative absence of researchers... for Federal Assistance, OMB Standard Form 424A, Budget Information--Non Construction Programs, OMB...

  4. Ethical review from the inside: repertoires of evaluation in Research Ethics Committee meetings.

    Science.gov (United States)

    de Jong, Jean Philippe; van Zwieten, Myra C B; Willems, Dick L

    2012-09-01

    Evaluating the practice of ethical review by Research Ethics Committees (REC) could help protect the interests of human participants and promote scientific progress. To facilitate such evaluations, we conducted an ethnographic study of how an REC reviews research proposals during its meetings. We observed 13 meetings of a Dutch REC and studied REC documents. We coded this material inductively and categorised these codes in two repertoires of evaluation: a repertoire of rules and a repertoire of production. In the repertoire of rules the REC applies rules, weighs scientific value and burdens to the participants and makes a final judgment on a research proposal in a meeting. In the repertoire of production, REC members check documents and forms and advise researchers on how to improve their proposals and can use informal communication. Based on these findings, we think that evaluations of the practice of ethical review should take into account the fact that RECs can use a repertoire of rules and a repertoire of production to evaluate research proposals. Combining these two repertoires can be a viable option so that the REC gives researchers advice on how to improve their proposals to prevent rejection of valuable research. © 2012 The Authors. Sociology of Health & Illness © 2012 Foundation for the Sociology of Health & Illness/Blackwell Publishing Ltd.

  5. The Changing Landscape of Lung Cancer Research and Treatment

    Science.gov (United States)

    Along with the Lung Cancer Social Media (#LCSM) community, the National Cancer Institute will be co-hosting a lively and interactive Google Hangout on Air about the changing landscape of lung cancer research and treatment. During the chat, viewers will have the opportunity to pose questions to a panel of lung cancer experts including NCI's Dr. Shakun Malik, the head of thoracic oncology therapeutics, Roy S. Herbst, MD, PhD, Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven and David Tom Cooke MD FACS, Head, Section of General Thoracic Surgery University of California, Davis. You can also learn more and follow along on the #LCSM Chat page. The chat will be moderated by lung cancer advocate and #LCSM co-founder, Janet Freeman-Daily. To ask questions of our experts, simply use the #LCSM hashtag during the chat.

  6. Clinical perspectives of cancer stem cell research in radiation oncology

    International Nuclear Information System (INIS)

    Bütof, Rebecca; Baumann, Michael; Dubrovska, Anna

    2013-01-01

    Radiotherapy has a proven potential to eradicate cancer stem cells which is reflected by its curative potential in many cancer types. Considerable progress has been made in identification and biological characterisation of cancer stem cells during the past years. Recent biological findings indicate significant inter- and intratumoural and functional heterogeneity of cancer stem cells and lead to more complex models which have potential implications for radiobiology and radiotherapy. Clinical evidence is emerging that biomarkers of cancer stem cells may be prognostic for the outcome of radiotherapy in some tumour entities. Perspectives of cancer stem cell based research for radiotherapy reviewed here include their radioresistance compared to the mass of non-cancer stem cells which form the bulk of all tumour cells, implications for image- and non-image based predictive bio-assays of the outcome of radiotherapy and a combination of novel systemic treatments with radiotherapy

  7. [Research progression of translational medicine in gastric cancer].

    Science.gov (United States)

    Li, Maoran; Zhao, Gang; Zhu, Chunchao

    2014-02-01

    Gastric cancer is one of the most common malignant tumors which is a great threat to human health. In recent years, the reform of surgical mordalities and the optimization of radiation and chemotherapy is still far from reducing morbidity and mortality of gastric cancer. As a new research pattern, translational medicine has emerged in various clinical subjects, which leads to remarkable effects. In this paper, the definition and development of translational medicine, molecular markers and drug treatment of gastric cancer will be discussed and the feasibility of translational medicine in the treatment of gastric cancer will be explained. In our opinion, the intervention of translational medicine could change the current situation that scientific researches is severely disconnected with clinical practice and increase the detection rate of gastric cancer and the effective rate of adjuvant therapy after surgery to improve the prognosis of patients with gastric cancer.

  8. Summer Student Breast Cancer Research Training Program

    National Research Council Canada - National Science Library

    Zaloga, Gary P

    2005-01-01

    .... Methyl and ethyl forms of omega-3 lipids failed to induce apoptosis. Ganoderma lucidum, a Chinese mushroom, was found to inhibit breast cancer cell growth and decrease EGF receptor phosphorylation...

  9. Chromatin Pioneers | Center for Cancer Research

    Science.gov (United States)

    Taking advantage of their ability to explore provocative ideas, NCI investigators pioneered the study of chromatin to demonstrate its functional importance and lay the groundwork for understanding its role in cancer and other diseases.

  10. Cellular Imaging | Center for Cancer Research

    Science.gov (United States)

    Innovative imaging methods developed and refined within CCR revealed atomic-level structures of biological molecules and unveiled dynamic views of a cell’s interior that are driving the design of new treatments and diagnostics for cancer.

  11. Evidence and research in rectal cancer.

    NARCIS (Netherlands)

    Valentini, V.; Beets-Tan, R.G.; Borras, J.M.; Krivokapic, Z.; Leer, J.W.H.; Pahlman, L.; Rodel, C.; Schmoll, H.J.; Scott, N.; Velde, C.V.; Verfaillie, C.

    2008-01-01

    The main evidences of epidemiology, diagnostic imaging, pathology, surgery, radiotherapy, chemotherapy and follow-up are reviewed to optimize the routine treatment of rectal cancer according to a multidisciplinary approach. This paper reports on the knowledge shared between different specialists

  12. Cancer Prevention and Control Research Manpower Development

    Science.gov (United States)

    1996-10-01

    the Maternal and Child Health/ Teenage Pregnancy Section of the National AHEC Conference, Louisville, Kentucky, June 11-14, 1989. 7. Taylor B, Griffith...34 Rev.Env.Contam.and Toxicol. 129:29-50. 1992. 13. Levine RS and Dolin P. " Pregnancy and Breast Cancer: A Possible Explanation for the Negative Association...diagnosis of cancer, poverty , and limited access to quality care.4 In California, African American women are at least 10% more likely than white women to be

  13. Breast Cancer Translational Research Center of Excellence

    Science.gov (United States)

    2017-11-01

    st century in the crusade against breast disorders. The project will continue utilizing a multidisciplinary approach as the standard of care for...on decreasing the morbidity and mortality of breast cancer among American women. 15. SUBJECT TERMS Biorepository, Biomedical Informatics, Focused...morbidity and mortality of breast cancer among American women with a specific focus on the problem as it pertains to the active duty military

  14. Policy challenges for cancer research: a call to arms.

    Science.gov (United States)

    Sullivan, R

    2007-01-01

    Research has delivered remarkable benefits for cancer patients and their families since James Watson and Francis Crick wrote the now immortal line, 'We wish to propose a structure for the salt of deoxyribonucleic acid' thus setting the molecular foundations for the modern era of cancer control. The pace of technological innovation from fundamental scientific discoveries to the policy impact of huge population studies has been breathtaking. One has only to contrast a paper on the treatment of solid epithelial cancers written by Henri Tagnon and colleagues in 1966 (Eur J Cancer2 51-7) with the myriad of chemotherapeutic approaches at the oncologists disposal today. Inevitably, as the tide of research has risen so it has bought the flotsam and jetsam of regulations and policies. Some have been helpful, many pointless and too many actually harmful. Naturally, some of these regulatory and general policies (by this I mean those concerned with funding, structure and organization) have been specifically targeted at cancer research, e.g. US National Cancer Act 1971, whilst others have been a product of the general regulatory environment with indirect consequences for cancer research, e.g. EU Data Protection Directive 1995. Policy issues thus cover a vast terrain criss-crossed by complex interdependencies between scientific areas, countries S&T policies and socio-political constructs. Unfortunately, there has been little attention paid to the consequences of these policy issues from which the research community has, by and large, been passenger rather than driver.Global investment in cancer research is now at unprecedented levels. The recently published report by the European Cancer Research Managers Forum has found some 14 billion euros being annually spent worldwide on cancer research (this figure includes industry but overall probably underestimates spend by at least one billion [2]). With the ageing demographics of developed countries and the catch-up effect in

  15. Cancer Deep Phenotyping Extraction from Electronic Medical Records | Informatics Technology for Cancer Research (ITCR)

    Science.gov (United States)

    As sequencing costs continue to decline, a torrent of cancer genomic data is looming. Very soon, our ability to deeply investigate the cancer genome will outpace our ability to correlate these changes with the phenotypes that they produce. We propose the advanced development and extension of a software platform for performing deep phenotype extraction directly from clinical text of cancer patients, with the goal of enabling translational cancer research and precision medicine.

  16. Summary of Prioritized Research Opportunities: Building America Program Planning Meeting, Washington, D.C., November 2-4, 2010

    Energy Technology Data Exchange (ETDEWEB)

    2011-02-01

    This report outlines the results of brainstorming sessions conducted at the Building America Fall 2010 planning meeting, in which research teams and national laboratories identified key research priorities to incorporate into multi-year planning, team research agendas, expert meetings, and technical standing committees.

  17. Biomedical text mining and its applications in cancer research.

    Science.gov (United States)

    Zhu, Fei; Patumcharoenpol, Preecha; Zhang, Cheng; Yang, Yang; Chan, Jonathan; Meechai, Asawin; Vongsangnak, Wanwipa; Shen, Bairong

    2013-04-01

    Cancer is a malignant disease that has caused millions of human deaths. Its study has a long history of well over 100years. There have been an enormous number of publications on cancer research. This integrated but unstructured biomedical text is of great value for cancer diagnostics, treatment, and prevention. The immense body and rapid growth of biomedical text on cancer has led to the appearance of a large number of text mining techniques aimed at extracting novel knowledge from scientific text. Biomedical text mining on cancer research is computationally automatic and high-throughput in nature. However, it is error-prone due to the complexity of natural language processing. In this review, we introduce the basic concepts underlying text mining and examine some frequently used algorithms, tools, and data sets, as well as assessing how much these algorithms have been utilized. We then discuss the current state-of-the-art text mining applications in cancer research and we also provide some resources for cancer text mining. With the development of systems biology, researchers tend to understand complex biomedical systems from a systems biology viewpoint. Thus, the full utilization of text mining to facilitate cancer systems biology research is fast becoming a major concern. To address this issue, we describe the general workflow of text mining in cancer systems biology and each phase of the workflow. We hope that this review can (i) provide a useful overview of the current work of this field; (ii) help researchers to choose text mining tools and datasets; and (iii) highlight how to apply text mining to assist cancer systems biology research. Copyright © 2012 Elsevier Inc. All rights reserved.

  18. Major clinical research advances in gynecologic cancer in 2013.

    Science.gov (United States)

    Suh, Dong Hoon; Kim, Jae-Weon; Kang, Sokbom; Kim, Hak Jae; Lee, Kyung-Hun

    2014-07-01

    In 2013, 10 topics were selected for major clinical research advances in gynecologic oncology; these included three topics regarding cervical cancer, three regarding ovarian cancer, two regarding endometrial cancer, and one each regarding breast cancer and radiation oncology. For cervical cancer, bevacizumab was first demonstrated to exhibit outstanding clinical efficacy in a recurrent, metastatic setting. Regarding cervical cancer screening, visual inspections with acetic acid in low-resource settings, p16/Ki-67 double staining, and the follow-up results of four randomized controlled trials of human papillomavirus-based screening methods were reviewed. Laparoscopic para-aortic lymphadenectomy before chemoradiation for locally advanced cervical cancer was the final topic for cervical cancer. Regarding front-line ovarian cancer therapies, dose-dense paclitaxel and carboplatin, intraperitoneal chemotherapy, and other targeted agents administered according to combination or maintenance schedules were discussed. Regarding recurrent ovarian cancer treatment, cediranib, olaparib, and farletuzumab were discussed for platinum-sensitive disease. The final overall survival data associated with a combination of bevacizumab and chemotherapy for platinum-resistant disease were briefly summarized. For endometrial cancer, the potential clinical efficacy of metformin, an antidiabetic drug, in obese patients was followed by integrated genomic analyses from the Cancer Genome Atlas Research Network. For breast cancer, three remarkable advances were reviewed: the long-term effects of continued adjuvant tamoxifen for 10 years, the effects of 2-year versus 1-year adjuvant trastuzumab for human epidermal growth factor receptor 2-positive disease, and the approval of pertuzumab in a neoadjuvant setting with a pathologic complete response as the surrogate endpoint. Finally, the recent large studies of intensity-modulated radiotherapy for gynecologic cancer were briefly summarized.

  19. The Future of Prostate Cancer Research and Treatment

    Science.gov (United States)

    On January 12, 2017 prostate cancer experts William Dahut, M.D. of the National Cancer Institute and Dr. Heather Cheng, M.D. of the University of Washington had a vibrant discussion about current and future research areas and treatment options for prostate cancer. The panel was moderated by Ana Fadich, MPH, CHES Vice President at Men’s Health of the Men's Health Network.

  20. Ethical, Legal, and Social Implication of Cancer Research | Resources | CDP

    Science.gov (United States)

    The Cancer Diagnosis Program strives to improve the diagnosis and assessment of cancer by effectively moving new scientific knowledge into clinical practice. This national program stimulates, coordinates and funds resources and research for the development of innovative in vitro diagnostics, novel diagnostic technologies and appropriate human specimens in order to better characterize cancers and allow improved medical decision making and evaluation of response to treatment.

  1. Second Research Coordination Meeting on Heavy Charged-Particle Interaction Data for Radiotherapy. Summary Report

    International Nuclear Information System (INIS)

    Palmans, Hugo; Noy, Roberto Capote

    2010-05-01

    A summary is given of the 2nd Research Coordination Meeting (RCM) on Heavy Charged-Particle Interaction Data for Radiotherapy. The programme to compile and evaluate charged-particle nuclear data for therapeutic applications was reviewed. Technical discussions and the resulting work plan of the Coordinated Research Programme are summarized, along with planned actions and deadlines. Participants' reports at the 2nd RCM are also included in this report. (author)

  2. Nuclear data for the production of therapeutic radionuclides. Summary report of third research coordination meeting

    International Nuclear Information System (INIS)

    Sublet, J.-Ch.; Capote Noy, R.

    2006-08-01

    A summary is given of the Third Research Coordination Meeting on Nuclear Data for the Production of Therapeutic Radionuclides. The new library of evaluated cross-section will cover reactor and accelerator production of therapeutic radionuclides to appropriate specific activities and purity, along with the relevant decay data. A few new reactions were added at this meeting. Technical discussions and the resulting work plan to conclude the data evaluation activities are summarized for every reaction path. Timescales and agreed actions to deliver the database and Technical Report are also given. (author)

  3. Graphic Evolution Witness the Development of Lung Cancer Translational Research

    Directory of Open Access Journals (Sweden)

    Chao ZHANG

    2016-06-01

    Full Text Available Lung cancer treatment has altered from conventional chemotherapy to targeted treatment, which now has been turned to the immunotherapy. Translational research has played an irreplaceable role during this progression which graphic evolution has witnessed. The evolution has gone through forest plot, KM-curve, waterfall plot, spider plot and timeline-area, showing us the refining concept and gradual process of lung cancer treatment undergoing from community towards individual. Even though the latest immunotherapy is getting increasingly hot, the result isn’t quite expected. Meanwhile, the limitations of conventional treatment still exist which require further research. This article will primarily illustrate the development of translational research of lung cancer via the aspect of curve evolution and analysis some abortive clinical trials in lung cancer surgery for inspiring the next graphic style and lung cancer treatment.

  4. Research reactor instrumentation and control technology. Report of a technical committee meeting

    International Nuclear Information System (INIS)

    1997-10-01

    The majority of research reactors operating today were put into operation 20 years ago, and some of them underwent modifications, upgrading and refurbishing since their construction to meet the requirements for higher neutron fluxes. However, a few of these ageing research reactors are still operating with their original instrumentation and control systems (I and C) which are important for reactor safety to guard against abnormal occurrences and reactor control involving startup, shutdown and power regulation. Worn and obsolete I and C systems cause operational problems as well as difficulties in obtaining replacement parts. In addition, satisfying the stringent safety conditions laid out by the nuclear regulatory bodies requires the modernization of research reactors I and C systems and integration of additional instrumentation units to the reactor. In order to clarify these issues and to provide some guidance to reactor operators on state-of-art technology and future trends for the I and C systems for research reactors, a Technical Committee Meeting on Technology and Trends for Research Reactor Instrumentation and Controls was held in Ljubljana, Slovenia, from 4 to 8 December 1995. This publication summarizes the discussions and recommendations resulting from that meeting. This is expected to benefit the research reactor operators planning I and C improvements. Refs, figs, tabs

  5. Proceedings of the meeting and scientific presentations on basic science research and nuclear technology

    International Nuclear Information System (INIS)

    Prayitno; Slamet Santosa; Darsono; Syarip; Agus Taftazani; Samin; Tri Mardji Atmono; Dwi Biyantoro; Herry Poernomo; Prajitno; Tjipto Sujitno; Gede Sutresna W; Djoko Slamet Pujorahardjo; Budi Setiawan; Bambang Siswanto; Endro Kismolo; Jumari

    2016-08-01

    The Proceedings of the Meeting and Scientific Presentations on Basic Science Research and Nuclear Technology by Center for Accelerator Science and Technology in Yogyakarta with the theme of Universities and research and development institutions synergy in the development of basic science and nuclear technology held on Surakarta 9 August 2016. This seminar is an annual routine activities of Center for Accelerator Science and Technology for exchange research result among University and BATAN researcher for using nuclear technology. The proceeding consist of 3 article from keynotes’ speaker and 37 articles from BATAN participant as well as outside which have been indexed separately. (MPN)

  6. IGORR 2: Proceedings of the 2. meeting of the International Group On Research Reactors

    International Nuclear Information System (INIS)

    1992-01-01

    The International group on Research Reactors was formed to facilitate the sharing of knowledge and experience among those institutions and individuals who are actively working to design, build, and promote new research reactors or to make significant upgrades to existing facilities. Sessions during this second meeting were devoted to research reactor reports (GRENOBLE reactor, FRM-II, HIFAR, PIK, reactors at JAERI, MAPLE, ANS, NIST, MURR, TRIGA, BR-2, SIRIUS 2); other neutron sources; and two workshops were dealing with research and development results and needs and reports on progress in needed of R and D areas identified at IGORR 1

  7. Nuclear data for the production of therapeutic radionuclides. Summary report of first research coordination meeting

    International Nuclear Information System (INIS)

    Sublet, J.-Ch.; Paviotti-Corcuera, R.

    2003-06-01

    Presentations, discussions and conclusions from the First Co-ordination Meeting on Nuclear Data for the Production of Therapeutic Radionuclides are summarised in this report. The main purpose of the meeting was to discuss scientific and technical matters related to the subject and to co-ordinate related tasks. Programmes of work were agreed and assigned, and deadlines were set. Participants emphasized the importance of the completeness and accuracy of the resulting nuclear data for the production of these radionuclides to appropriate specific activities and purity along with the relevant decay data. The recommended data from this Coordinated Research Project should meet the requirements for the safe and efficacious application of therapeutic treatments in nuclear medicine. (author)

  8. Advancing novel HIV prevention intervention research with MSM--meeting report.

    Science.gov (United States)

    Grossman, Cynthia I; Forsyth, Andrew; Purcell, David W; Allison, Susannah; Toledo, Carlos; Gordon, Christopher M

    2011-01-01

    HIV continues to exact an enormous toll on society and to disproportionately affect gay and bisexual men and other men who have sex with men (MSM). Innovative prevention interventions are needed to reverse this trend. In August 2009, the U.S. National Institute of Mental Health and the Centers for Disease Control and Prevention convened a meeting of scientists, community representatives, advocates, and federal partners to discuss innovative prevention-intervention science. The meeting was structured to maximize discussion of (1) healthy sex interventions, (2) community and structural interventions, (3) integrated biomedical and behavioral interventions, and (4) interventions to improve uptake of HIV testing. Presentations and discussion focused on research gaps in designing risk-reducing and sexual health-promoting interventions for MSM, including interventions to address mental health, substance use, disclosure, and stigma. This article summarizes the meeting proceedings, highlights key points, and outlines future directions.

  9. Identification of a Novel Cancer Biomarker | Center for Cancer Research

    Science.gov (United States)

    During cancer development, cells accumulate a variety of mutations which alter their normal components and activities. One potential change is in the carbohydrate or sugar polymers which decorate proteins predominately found on the cell surface. The accessibility of these residues makes them ideal targets for the development of diagnostics or therapeutics.

  10. Development, implementation and evaluation of a multidisciplinary cancer rehabilitation programme : The CANSURVIVOR Project : meeting post-treatment cancer survivors’ needs

    LENUS (Irish Health Repository)

    Ivers, Mary E.

    2009-01-01

    Cancer survivor numbers in Ireland are increasing due to the success of modern treatments. Although most survivors have a good quality of life not all survivors return to \\'normal\\' after treatment. The HSE funded CANSURVIVOR research project has found that many survivors have difficulties and need help to recover and adjust after cancer treatment. Over a number of exploratory studies using interviews, focus groups and a survey of 262 breast, prostate, colorectal and lung cancer survivors, the researchers found that over 25% of survivors experienced significant difficulties with physical, emotional and social functioning, including symptoms such as insomnia and fatigue, while 33% experienced high levels of anxiety. Of particular concern were the findings that over 50% of survivors were overweight, 35% had reduced their physical activity levels and 13% continued to smoke after cancer, putting them at risk for further health problems. This evidence led to the development of an 8-week multi-disciplinary pilot rehabilitation programme. Significant quality of life improvements were achieved with increases in strength and fitness as well as a reduction in anxiety levels and dietary improvements. The researchers highlight the need for a structured, co-ordinated survivorship service, education of health professionals about survivorship and the provision of high quality information to survivors. This research was led by the School of Psychology at UCD in collaboration with the Physiotherapy and Nutrition departments of St. Vincent\\'s hospital.

  11. The John Milner Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

    Science.gov (United States)

    Attendee Testimonial Plenty of Food for Thought Served Up at the John Milner Nutrition and Cancer Prevention Research Practicum by Julia Tobacyk Media Folder: research_groupView the Testimonial (PDF, 790 KB) Date: March 12-16, 2018 |

  12. Online cancer communication: meeting the literacy, cultural and linguistic needs of diverse audiences.

    Science.gov (United States)

    Neuhauser, Linda; Kreps, Gary L

    2008-06-01

    This article provides an analysis of issues and empirical evidence related to literacy, cultural, and linguistic factors in online health and cancer communication, and recommendations to improve cancer communication for diverse audiences. We examined English-language online literature and selected books and policy documents related to literacy, cultural, and linguistic factors in health and cancer communication. Studies about literacy, cultural, and linguistic factors in online cancer communication for diverse audiences are limited, but have increased during the past 15 years. Empirical evidence and theoretical guidance describe the critical importance of these factors, significant unmet needs among low-literate, multicultural and non-English-speaking populations, and strategies to improve communication. Overall, online cancer communication has not met the literacy, cultural, and linguistic needs of diverse populations. The literature offers valuable recommendations about enhancing research, practice, and policy for better cancer communication. Practitioners should understand the strengths and weaknesses of online cancer communication for vulnerable groups, guide patients to better Websites, and supplement that information with oral and tailored communication.

  13. Big data for population-based cancer research: the integrated cancer information and surveillance system.

    Science.gov (United States)

    Meyer, Anne-Marie; Olshan, Andrew F; Green, Laura; Meyer, Adrian; Wheeler, Stephanie B; Basch, Ethan; Carpenter, William R

    2014-01-01

    The Integrated Cancer Information and Surveillance System (ICISS) facilitates population-based cancer research by developing extensive information technology systems that can link and manage large data sets. Taking an interdisciplinary 'team science' approach, ICISS has developed data, systems, and methods that allow researchers to better leverage the power of big data to improve population health.

  14. Cancer research in India: national priorities, global results.

    Science.gov (United States)

    Sullivan, Richard; Badwe, Rajendra A; Rath, Goura K; Pramesh, C S; Shanta, V; Digumarti, Raghunadharao; D'Cruz, Anil; Sharma, Suresh C; Viswanath, Lokesh; Shet, Arun; Vijayakumar, Manavalan; Lewison, Grant; Chandy, Mammen; Kulkarni, Priyadarshini; Bardia, M R; Kumar, Shaleen; Sarin, Rajiv; Sebastian, Paul; Dhillon, Preet K; Rajaraman, Preetha; Trimble, Edward L; Aggarwal, Ajay; Vijaykumar, D K; Purushotham, Arnie D

    2014-05-01

    Over the past 20 years, cancer research in India has grown in size and impact. Clinicians, scientists, and government and state policy makers in India have championed cancer research, from studies to achieve low-tech, large-scale health outcomes to some of the most advanced areas of fundamental cancer science. In this paper, we frame public policy discussions about cancer with use of an in-depth analysis of research publications from India. Cancer research in India is a complex environment that needs to balance public policy across many competing agendas. We identify major needs across these environments such as those for increased research capacity and training and protected time for clinical researchers; for more support from states and enhanced collaborative funding programmes from government; for development of national infrastructures across a range of domains (ie, clinical trials, tissue banking, registries, etc); and for a streamlined and rational regulatory environment. We also discuss improvements that should be made to translate research into improvements in cancer outcomes and public health. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Kids, Adolescents, and Young Adults Cancer Study-A Methodological Approach in Cancer Epidemiology Research

    International Nuclear Information System (INIS)

    Link, N. L.; Maurer, E.; Largent, J.; Kent, E.; Sender, E.; Culver, H. A.; Morris, R. A.; Sender, E.

    2009-01-01

    Advances have been made in treatment and outcomes for pediatric cancer. However adolescents and young adults (AYAs) with cancer have not experienced similar relative improvements. We undertook a study to develop the methodology necessary for epidemiologic cancer research in these age groups. Our goal was to create the Kids, Adolescents, and Young Adults Cancer (KAYAC) project to create a resource to address research questions relevant to this population. We used a combination of clinic and population-based ascertainment to enroll 111 cases aged 0-39 for this methodology development study. The largest groups of cancer types enrolled include: breast cancer, leukemia, lymphoma, and melanoma. The overall participation rate is 69.8% and varies by age and tumor type. The study included patients, mothers, and fathers. The methods used to establish this resource are described, and the values of the resource in studies of childhood and young adult cancer are outlined.

  16. A survey of etiologic hypotheses among testicular cancer researchers

    DEFF Research Database (Denmark)

    Stang, A; Trabert, B; Rusner, C

    2015-01-01

    Basic research results can provide new ideas and hypotheses to be examined in epidemiological studies. We conducted a survey among testicular cancer researchers on hypotheses concerning the etiology of this malignancy. All researchers on the mailing list of Copenhagen Testis Cancer Workshops...... the plausibility of the suggested etiologic hypotheses on a scale of 1 (very implausible) to 10 (very plausible). This report describes the methodology of the survey, the score distributions by individual hypotheses, hypothesis group, and the participants' major research fields, and discuss the hypotheses...... and corresponding authors of PubMed-indexed articles identified by the search term 'testicular cancer' and published within 10 years (in total 2750 recipients) were invited to respond to an e-mail-based survey. Participants of the 8th Copenhagen Testis Cancer Workshop in May 2014 were subsequently asked to rate...

  17. [Recommendations for cancer prevention of World Cancer Research Fund (WCRF): situational analysis for Chile].

    Science.gov (United States)

    Crovetto, Mirta; Uauy, Ricardo

    2013-05-01

    The main diet-related cancers include colorectal, lung, breast in (postmenopausal) women, stomach, esophagus, prostate and pancreas. After tobacco, obesity is the leading cause of cancer; it accounts for one third of all cancers. Cancer is associated with high total body fat, abdominal fat and weight gain in adult life. These are all potentially modifiable risk factors. Consumption of a "healthy diet" and living an "active life" can significantly reduce the risk of cancer. The aim of this study was to analyze the recommendations published by the World Cancer Research Fund (WCRF) and American Institute for Cancer Research (AICR) for the prevention of cancer in 2007. We compared the recommendations of Food, Nutrition and Physical Activity and the Prevention of Cancer: a global perspective", with the national situation in Chile, analyzing the national report on the prevalence of risk factors. Our main finding was that the pattern of consumption and lifestyles differ markedly from the WCRF recommendations: we observed an over consumption of sugary drinks and high intake of processed foods high in sodium and total fat and low consumption of legumes, vegetables, fruits high in antioxidants and fiber that protect from cancer. Chile has an increased cancer prevalence which is associated with poor quality diets, rising mean body mass index and a sedentary behavior. We recommend the strengthening programs to promote healthy diets and active living, in order to reduce cancer risk.

  18. Cancer Prevention and Control Research Manpower Development

    Science.gov (United States)

    1999-10-01

    Teacher Educators 73rd Annual Meeting, Los Angeles, California Rowley, C. (1991, April). Suicide ideation and depression in chronically ill children: A...Florida Rowley, C., & Gilbert, B.O. (1991, May). Suicide ideation and depression in chronically ill children: A study of children and adolescents with...for preeclampsia in twin pregnancies: a population-based cohort study. Obstet Gynecol 1995;85:645-50. 17. Gu Y, He S, Shi L, Li 0, Zhu Kr, Yin Z, Wang

  19. A comparison of cancer burden and research spending reveals discrepancies in the distribution of research funding

    Directory of Open Access Journals (Sweden)

    Carter Ashley JR

    2012-07-01

    Full Text Available Abstract Background Ideally, the distribution of research funding for different types of cancer should be equitable with respect to the societal burden each type of cancer imposes. These burdens can be estimated in a variety of ways; “Years of Life Lost” (YLL measures the severity of death in regard to the age it occurs, "Disability-Adjusted Life-Years" (DALY estimates the effects of non-lethal disabilities incurred by disease and economic metrics focus on the losses to tax revenue, productivity or direct medical expenses. We compared research funding from the National Cancer Institute (NCI to a variety of burden metrics for the most common types of cancer to identify mismatches between spending and societal burden. Methods Research funding levels were obtained from the NCI website and information for societal health and economic burdens were collected from government databases and published reports. We calculated the funding levels per unit burden for a wide range of different cancers and burden metrics and compared these values to identify discrepancies. Results Our analysis reveals a considerable mismatch between funding levels and burden. Some cancers are funded at levels far higher than their relative burden suggests (breast cancer, prostate cancer, and leukemia while other cancers appear underfunded (bladder, esophageal, liver, oral, pancreatic, stomach, and uterine cancers. Conclusions These discrepancies indicate that an improved method of health care research funding allocation should be investigated to better match funding levels to societal burden.

  20. Clinical application and research of tumor markers in colorectal cancer

    International Nuclear Information System (INIS)

    Chen Yumei

    2005-01-01

    Colorectal cancer is one of the most common malignant tumors. There are many tumor markers for detecting colorectal cancer, some of which have been widely used in clinical area. However, still lack an ideal tumor marker of colorectal cancer. In this review, we simply characterized some common tumor markers including carcinoembryonic antigen, CA19-9, CA50, CA242 etc and their dignostic value. And here we discussed some combined detecting procedures which improve diagnostic accuracy of colorectal cancer. In addition, with the development of the biomoleculer technique, some newly discovered tumor markers and genetic marekers have gained great progress in the research of colorectal cancer, and will become a promissing technique in the diagnosis of colorectal cancer. (authors)

  1. Promising Tools in Prostate Cancer Research

    DEFF Research Database (Denmark)

    Bonomo, Silvia; Hansen, Cecilie H; Petrunak, Elyse M

    2016-01-01

    Cytochrome P450 17A1 (CYP17A1) is an important target in the treatment of prostate cancer because it produces androgens required for tumour growth. The FDA has approved only one CYP17A1 inhibitor, abiraterone, which contains a steroidal scaffold similar to the endogenous CYP17A1 substrates...

  2. Advances in cancer research. Volume 48

    Energy Technology Data Exchange (ETDEWEB)

    Klein, G.; Weinhouse, S.

    1987-01-01

    This book contains the following five selections: Oncotrophoblast Gene Expression: Placental Alkaline Phosphatase; Cellular Events during Hepatocarcinogenesis in Rats and the Questions of Premalignancy; Human Papillomaviruses and Genital Cancer; Herpes Simplex Type 2 Virus and Cervical Neoplasia; and Transforming Genes and Target Cells of Murine Spleen Focus-Forming Viruses.

  3. Testicular Cancer Survivorship : Research Strategies and Recommendations

    NARCIS (Netherlands)

    Travis, Lois B.; Beard, Clair; Allan, James M.; Dahl, Alv A.; Feldman, Darren R.; Oldenburg, Jan; Daugaard, Gedske; Kelly, Jennifer L.; Dolan, M. Eileen; Hannigan, Robyn; Constine, Louis S.; Oeffinger, Kevin C.; Okunieff, Paul; Armstrong, Greg; Wiljer, David; Miller, Robert C.; Gietema, Jourik A.; van Leeuwen, Flora E.; Williams, Jacqueline P.; Nichols, Craig R.; Einhorn, Lawrence H.; Fossa, Sophie D.

    2010-01-01

    Testicular cancer represents the most curable solid tumor, with a 10-year survival rate of more than 95%. Given the young average age at diagnosis, it is estimated that effective treatment approaches, in particular, platinum-based chemotherapy, have resulted in an average gain of several decades of

  4. Summer Undergraduate Breast Cancer Research Program

    National Research Council Canada - National Science Library

    Folk, William

    2002-01-01

    .... These students participated in faculty-mentored research projects for eight weeks and participated in seminars, brown-bag lunches, and specialty discussion on research, clinical trials, career...

  5. Functional Capacity Evaluation Research: Report from the Third International Functional Capacity Evaluation Research Meeting.

    Science.gov (United States)

    Edelaar, M J A; Gross, D P; James, C L; Reneman, M F

    2018-03-01

    Purpose Based on the success of the first two conferences the Third International FCE Research Conference was held in The Netherlands on September 29, 2016. The aim was to provide ongoing opportunity to share and recent FCE research and discuss its implications. Methods Invitations and call for abstracts were sent to previous attendees, researchers, practicing FCE clinicians and professionals. Fifteen abstracts were selected for presentation. The FCE research conference contained two keynote lectures. Results 54 participants from 12 countries attended the conference where 15 research projects and 2 keynote lectures were presented. The conference provided an opportunity to present and discuss recent FCE research, and provided a forum for discourse related to FCE use. Conference presentations covered aspects of practical issues in administration and interpretation; protocol reliability and validity; consideration of specific injury populations; and a focused discussion on proposed inclusion of work physiology principles in FCE testing with the Heart Rate Reserve Method. Details of this Third International FCE Research Conference are available from http://repro.rcnheliomare.nl/FCE.pdf . Conclusions Researchers, clinicians, and other professionals in the FCE area have a common desire to further improve the content and quality of FCE research and to collaborate to further develop research across systems, cultures and countries. A fourth, 2-day, International FCE research conference will be held in Valens, Switzerland in August or September 2018. A 'FCE research Society' will be developed.

  6. Development and testing of the cancer multidisciplinary team meeting observational tool (MDT-MOT).

    Science.gov (United States)

    Harris, Jenny; Taylor, Cath; Sevdalis, Nick; Jalil, Rozh; Green, James S A

    2016-06-01

    To develop a tool for independent observational assessment of cancer multidisciplinary team meetings (MDMs), and test criterion validity, inter-rater reliability/agreement and describe performance. Clinicians and experts in teamwork used a mixed-methods approach to develop and refine the tool. Study 1 observers rated pre-determined optimal/sub-optimal MDM film excerpts and Study 2 observers independently rated video-recordings of 10 MDMs. Study 2 included 10 cancer MDMs in England. Testing was undertaken by 13 health service staff and a clinical and non-clinical observer. None. Tool development, validity, reliability/agreement and variability in MDT performance. Study 1: Observers were able to discriminate between optimal and sub-optimal MDM performance (P ≤ 0.05). Study 2: Inter-rater reliability was good for 3/10 domains. Percentage of absolute agreement was high (≥80%) for 4/10 domains and percentage agreement within 1 point was high for 9/10 domains. Four MDTs performed well (scored 3+ in at least 8/10 domains), 5 MDTs performed well in 6-7 domains and 1 MDT performed well in only 4 domains. Leadership and chairing of the meeting, the organization and administration of the meeting, and clinical decision-making processes all varied significantly between MDMs (P ≤ 0.01). MDT-MOT demonstrated good criterion validity. Agreement between clinical and non-clinical observers (within one point on the scale) was high but this was inconsistent with reliability coefficients and warrants further investigation. If further validated MDT-MOT might provide a useful mechanism for the routine assessment of MDMs by the local workforce to drive improvements in MDT performance. © The Author 2016. Published by Oxford University Press in association with the International Society for Quality in Health Care; all rights reserved.

  7. Gastric cancer research in Mexico: a public health priority.

    Science.gov (United States)

    Sampieri, Clara Luz; Mora, Mauricio

    2014-04-28

    This study aimed review studies conducted on Mexican patients diagnosed with gastric cancer and/or diseases associated with its development, in which at least one Mexican institute has participated, and to assess their contributions to the primary and secondary prevention of this disease. A search of the Medline database was conducted using the following keywords: gastric/stomach cancer, Mexico. Studies of the Mexican population were selected in which at least one Mexican Institute had participated and where the findings could support public policy proposals directed towards the primary or secondary prevention of gastric cancer. Of the 148 studies found in the Medline database, 100 were discarded and 48 were reviewed. According to the analysis presented, these studies were classified as: epidemiology of gastric cancer (5/48); risk factors and protectors relating to gastric cancer (9/48); relationship between Helicobacter pylori and pathologies associated with gastric cancer and the development of the disease (16/48); relationship between the Epstein-Barr virus and pathologies associated with gastric cancer and the development of the disease (3/48); molecular markers for the development of diseases associated with gastric cancer and gastric cancer (15/48). Mexico requires a program for the prevention and control of gastric cancer based on national health indicators. This should be produced by a multidisciplinary committee of experts who can propose actions that are relevant in the current national context. The few studies of gastric cancer conducted on the Mexican population in national institutes highlight the poor connection that currently exists between the scientific community and the health sector in terms of resolving this health issue. Public policies for health research should support projects with findings that can be translated into benefits for the population. This review serves to identify national research groups studying gastric cancer in the Mexican

  8. Cancer in Africa: opportunities for collaborative research and training.

    Science.gov (United States)

    Adebamowo, C A; Akarolo-Anthony, S

    2009-06-01

    Cancer is a worldwide public health problem causing increasing morbidity and mortality, particularly in the developing world. Underlying trends are changing the pattern of cancer and this is also being influenced by the HIV/AIDS pandemic, particularly in Sub-Saharan Africa. Even though the pattern of cancer varies across Africa, there are identifiable trends. Breast and cervical cancers, and Kaposi sarcoma are the commonest cancers in women, while Kaposi sarcoma, liver and prostate cancers are the commonest in men. Cancer causes more morbidity and mortality in Africa compared to other parts of the world. Infections account for a disproportionate amount of cancers in Africa. The HIV epidemic is contributing to increased prevalence of many cancers particularly those associated with Herpes and Papilloma viruses. Tobacco use, another major carcinogen, is increasing, particularly among the young. Dietary factors, alcohol use, physical inactivity and environmental pollution are also important aetiological factors of cancer in Africa. In developing countries, poverty, limited government health budget and poor health care systems complicate cancer prevention, treatment and outcomes. Coordinated response by international agencies and NGOs is needed to help developing countries and several successful models exist. More action is also needed on ensuring safety and quality of chemotherapy and the price needs to be reduced. Responses advocated for cancer control in Africa include banning tobacco use, better regulation of alcohol sale, better environmental planning and immunization against cancer associated viruses. Training of health care workers to diagnose cancer and treat it effectively within limited budgets is needed. Research to develop these new treatments and others, particularly from natural products is urgently needed and this can be done safely within established health research ethics regulatory frameworks. Several opportunities for collaborative research and

  9. Summary Report of the First Research Coordination Meeting on Primary Radiation Damage Cross Sections

    International Nuclear Information System (INIS)

    Stoller, R.E.; Greenwood, L.R.; Simakov, S.P.

    2013-12-01

    The Nuclear Data Section of IAEA has initiated a new Coordinated Research Project with the main goal of reviewing and recommending primary damage response functions for neutron and ion irradiations of materials. The output of this CRP will be a database of recommended damage response functions for selected materials with corresponding documentation. It will serve the needs of the fission, fusion and accelerator neutron source communities. The first Research Coordination Meeting (RCM) was held 4 to 8 November 2013 at the IAEA. At this meeting, the attendees discussed the objectives of the whole CRP, presented their contributions and elaborated on consolidated recommendations and actions for implementation over the next 1.5 year period. This Summary Report documents the individual contributions and joint decisions made during this meeting. The identified research needs were refined through extensive discussion, and a consensus was developed which defined the CRP objectives in two broad categories. The first addresses the underlying physics-related research relevant to nuclear reactions and ion stopping powers, while the second task will address the development of new materials damage response functions. (author)

  10. Statistical study on cancer patients of cancer research hospital

    International Nuclear Information System (INIS)

    Shim, Yun Sang; Choi, Soo Yong; Kim, Ki Wha; Kang, Sung Mok

    1993-01-01

    The total number of malignant neoplasms included in this study 15,737 cases(11.8%) among 133,251 cases for 3 years. On sex, females with 52.9% were much more than males with 47.1%. The highest proportion of cancer patients by age was 33.7% in males and 28.5% in females, respectivelty for 50-59 age group. The most frequent primary site among males was found to be stomach with 35.5%, followed by liver(14.7%), lung(13.0%), esophagus(5.4%) and colon (3.2%). In females, the first order was uterine cervix with 40.6%, followed by stomach(17.2%), breast(14.4), rectum(3.7%) and lung(3.4%). The most common type of morphology of malignant neoplasms was adenocarcinoma(47.4%) in males an squamous cell carcinoma(58.0%) in females. Among the cancer patients initially diagnosed in this hospital, the proportion of malignant neoplasms by the exent of disease was 2.5% for patient with carcinoma-in-situ, 54.1% for patients with localized involvement, 13.3% for patients with regional involvement and 8.5% for patients with distant involvement. Among the cancer patients initially treatment in this hospital, the proportion of malignant neoplasms by the method of treatment was 23.6% for surgery, 25.3% for radiotherapy and 30.3% for chemotherapy. Among the cancer patients confirmed by medical records, 7.7% was traced more than 5 years. (Author)

  11. Lipid Biomarkers Identified for Liver Cancer | Center for Cancer Research

    Science.gov (United States)

    Hepatocellular carcinoma (HCC) is an aggressive cancer of the liver with poor prognosis and growing incidence in developed countries. Pathology and genetic profiles of HCC are heterogeneous, suggesting that it can begin growing in different cell types. Although human tumors such as HCC have been profiled in-depth by genomics-based studies, not much is known about their overall metabolite modifications and how these changes can form a network that leads to aggressive disease and poor outcome.

  12. ESNA: European Society for New Methods in Agricultural Research. 23. annual meeting and 3. German meeting on food irradiation. Book of abstracts

    International Nuclear Information System (INIS)

    1993-01-01

    The book comprises 181 abstracts of the 23rd Annual Meeting of the European Society for New Methods in Agricultural Research and the 3rd German Meeting on Food Irradiation. The following subjects were discussed in six workshops: Radiation Technology and 3rd German Meeting on Food Irradiation (44); Advanced Methods in Animal Sciences (17); Soil-Plant Relationships (36); Plant Genetics, Breeding and Physiology (48); Environmental Aspects and Energy Use (16); Pest Management (20). The abstracts are supplemented by an alphabetic index of authors. (UHE) [de

  13. Electron Microscopist/Structural Biologist | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI’s intramural Center for Cancer Research (CCR). The dedicated units provide electron microscopy, protein characterization, protein expression, optical microscopy and genetics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR). CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise. KEY ROLES/RESPONSIBILITIES - THIS POSITION IS CONTINGENT UPON FUNDING APPROVAL Develop technologies for application on emerging electron microscopy platforms. Operate and optimize performance of TEM microscopes, specifically Titan Krios and Talos Artctica for high-resolution data collection in single particle studies as well as cryo-electron tomography. Assist with maintenance for the Titan Krios and the Talos Arctica as well as associated instruments. Interact closely with and transfer newly developed technical capabilities to CCR Center for Molecular Microscopy (CMM) and CCR collaborators.

  14. Development of a reference database for ion beam analysis. Summary report of the first research coordination meeting

    International Nuclear Information System (INIS)

    Vickridge, I.; Schwerer, O.

    2006-01-01

    A summary is given of the First Research Coordination Meeting on the Development of a Reference Database for Ion Beam Analysis, including background information, objectives, recommendations for measurements, and a list of tasks assigned to participants. The next research co-ordination meeting will be held in May 2007. (author)

  15. Proceedings of the 1978 international meeting on reduced enrichment for research and test reactors

    International Nuclear Information System (INIS)

    Travelli, A.

    1993-08-01

    November 9-10, 1978, marked the first of what has become an annual event - the International Meeting on Reduced Enrichment for Research and Test Reactors (RERTR). The RERTR Program had been started only three months earlier, and the meeting brought together for the first time many people who became major program participants in later years. This first meeting emphasized fuel development, and while it established the basis for all later meetings, it was unique in several respects. It was a time of feeling each other out, and of sharing new ideas, concerns, and hopes. In the absence of an established precedent, a number of participants came with written papers while others made only verbal presentations. Informality added spice and special importance to the discussions at the end of each presentation and, especially, to the panel discussion at the end of the meeting. An important achievement was a consensus on near-, medium-, and long-term density goals for the various fuels. This consensus resulted in a list written on the blackboard at the end of the panel discussion, and reproduced on page 216, which outlined the goals of each fabricator. Luckily, both presentations and discussions were recorded on audio tape. These recordings were transcribed and used to complete the informal presentations and to append the discussions at the end of each presentation. Considerable effort was expended in clearing the transcribed papers and key discussions with the participants. A few issues could not be resolved quickly, and in the frantic rush of those early years, these proceedings were set aside. Believing that the proceedings of this first meeting are important as a historical record of the beginning of the international RERTR effort, we have recently dusted off the manuscript and finished our editing job

  16. What does it mean to be genomically literate?: National Human Genome Research Institute Meeting Report.

    Science.gov (United States)

    Hurle, Belen; Citrin, Toby; Jenkins, Jean F; Kaphingst, Kimberly A; Lamb, Neil; Roseman, Jo Ellen; Bonham, Vence L

    2013-08-01

    Genomic discoveries will increasingly advance the science of medicine. Limited genomic literacy may adversely impact the public's understanding and use of the power of genetics and genomics in health care and public health. In November 2011, a meeting was held by the National Human Genome Research Institute to examine the challenge of achieving genomic literacy for the general public, from kindergarten to grade 12 to adult education. The role of the media in disseminating scientific messages and in perpetuating or reducing misconceptions was also discussed. Workshop participants agreed that genomic literacy will be achieved only through active engagement between genomics experts and the varied constituencies that comprise the public. This report summarizes the background, content, and outcomes from this meeting, including recommendations for a research agenda to inform decisions about how to advance genomic literacy in our society.

  17. What Does it Mean to be Genomically Literate? National Human Genome Research Institute Meeting Report

    Science.gov (United States)

    Hurle, Belen; Citrin, Toby; Jenkins, Jean F.; Kaphingst, Kimberly A.; Lamb, Neil; Roseman, Jo Ellen; Bonham, Vence L.

    2014-01-01

    Genomic discoveries will increasingly advance the science of medicine. Limited genomic literacy may adversely impact the public’s understanding and use of the power of genetics and genomics in health care and public health. In November 2011, a meeting was held by the National Human Genome Research Institute to examine the challenge of achieving genomic literacy for the general public, from K-12 to adult education. The role of the media in disseminating scientific messages and in perpetuating, or reducing, misconceptions was also discussed. Workshop participants agreed that genomic literacy will only be achieved through active engagement between genomics experts and the varied constituencies that comprise the public. This report summarizes the background, content, and outcomes from this meeting, including recommendations for a research agenda to inform decisions about how to advance genomic literacy in our society. PMID:23448722

  18. Nutritional genomic approaches to cancer prevention research.

    Science.gov (United States)

    Ross, S A

    2007-12-01

    A wealth of evidence points to the diet as one of the most important modifiable determinants of the risk of developing cancer, but a greater understanding of the interaction between diet and genes may help distinguish who will and will not respond to dietary interventions. The term nutrigenomics or nutritional genomics refers to the bidirectional interactions between genes and diet. Nutritional genomics encompasses an understanding about how the response to bioactive food components depends on an individual's genetic background (nutrigenetics), nutrient induced changes in DNA methylation, histone posttranslational modifications, and other chromatin alterations (nutritional epigenetics), and nutrient induced changes in gene expression (nutritional transcriptomics). These approaches to the study of nutrition will assist in understanding how genetic variation, epigenetic events, and regulation of gene expression alter requirements for, and responses to, nutrients. Recognition of the interplay between genes and diet could ultimately help identify modifiable molecular targets for preventing, delaying, or reducing the symptoms of cancer and other chronic diseases.

  19. MBCP - Approach - Immunotherapy | Center for Cancer Research

    Science.gov (United States)

    Immunotherapy CCR investigators pioneered the use of the tuberculosis vaccine—Bacillus Calmette-Guerin (BCG)—in the treatment of bladder cancer. In cases where the tumor burden is not too high and direct contact can be made with the urothelium surface of the bladder, BCG application appears to elicit an immune response that attacks the tumor as well as the attenuated virus. Ongoing clinical trials focusing on enhancing the patient’s immune system are listed below.

  20. G.I. Joe Meets Barbie, Software Engineer Meets Caregiver: Males and Females in B.C.'s Public Schools and Beyond. BCTF Research Report.

    Science.gov (United States)

    Schaefer, Anne C.

    Following a referral from the March 2000 Annual General Meeting of the British Columbia (B.C.) Teachers' Federation, the Spring 2000 Representative Assembly passed a motion that recommended research be collected, conducted, and disseminated on the current status of students in the province. This research report identifies current information on…