WorldWideScience

Sample records for cancer research institute

  1. Peralta Cancer Research Institute

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    The investigators in the cell biology program at PCRI have pioneered in the development of techniques for culturing human epithelial cells. The cancer diagnosis program has been concerned with researching new techniques for early diagnosis of breast cancer in women. The cancer treatment program has been concerned with applying cell biology and biochemistry advances to improve cancer management

  2. American Institute for Cancer Research

    Science.gov (United States)

    INFOGRAPHICS RECIPES FOODS THAT FIGHT CANCER SHOP Donate Now Planned Giving Memorial Gifts Car Donations Home Reduce Your Cancer Risk Diet How healthy is your diet? A cancer-protective diet Healthy recipes Nutrition facts Phytochemicals in ...

  3. Adherence to the World Cancer Research Fund/American Institute for Cancer Research lifestyle recommendations in colorectal cancer survivors

    NARCIS (Netherlands)

    Winkels, Renate M.; Lee, van Linde; Beijer, Sandra; Bours, Martijn J.; Duijnhoven, van Fränzel J.B.; Geelen, Anouk; Hoedjes, Meeke; Mols, Floortje; Vries, de Jeanne; Weijenberg, Matty P.; Kampman, Ellen

    2016-01-01

    We examined adherence to the eight The World Cancer Research Foundation/American Institute for Cancer Research (WCRF/AICR) recommendations on diet, physical activity, and body weight among colorectal cancer survivors, and whether adherence was associated with intention to eat healthy and with the

  4. Cooperative research and development opportunities with the National Cancer Institute

    Science.gov (United States)

    Sybert, Kathleen

    1991-01-01

    The Office of Technology Development (OTD) of the National Cancer Institute (NCI) is responsible for negotiating Cooperative Research and Development Agreements (CRADAs), whereby the knowledge resulting from NCI investigators' government-sponsored research is developed in collaboration with universities and/or industry into new products of importance for the diagnosis and treatment of cancer and acquired immunodeficiency syndrome (AIDS). The NCI has recently executed a unique 'clinical trials' CRADA and is developing a model agreement based upon it for the development and commercialization of products for the diagnosis and treatment of cancer and AIDS. NCI drug screening, preclinical testing, clinical trials, and AIDS program capabilities form the basis for this new technology development/technology transfer vehicle. NCI's extensive drug screening program and 'designer foods' program serve as potential sources of investigational new drugs (INDs) and cancer preventatives. Collaborations between NCI and pharmaceutical companies having the facilities, experience, and expertise necessary to develop INDs into approved drugs available to the public are being encouraged where the companies have proprietary rights to INDs, or where NCI has proprietary rights to INDs and invites companies to respond to a collaborator announcement published in the Federal Register. The joint efforts of the NCI and the chosen collaborator are designed to generate the data necessary to obtain pharmaceutic regulatory approval from the Food and Drug Administration (FDA) to market the drugs developed, and thereby make them available to health care providers for the diagnosis and treatment of cancer and AIDS.

  5. Adherence to the World Cancer Research Fund/American Institute for Cancer Research recommendations and colorectal cancer risk.

    Science.gov (United States)

    Turati, Federica; Bravi, Francesca; Di Maso, Matteo; Bosetti, Cristina; Polesel, Jerry; Serraino, Diego; Dalmartello, Michela; Giacosa, Attilio; Montella, Maurizio; Tavani, Alessandra; Negri, Eva; La Vecchia, Carlo

    2017-11-01

    The World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) released in 2007 eight recommendations for cancer prevention on body fatness, diet and physical activity. Our aim is to evaluate the relation between adherence to these recommendations and colorectal cancer (CRC) risk. We pooled data from two Italian case-control studies including overall 2419 patients with CRC and 4723 controls. Adherence to the WCRF/AICR guidelines was summarised through a score incorporating seven of the WCRF/AICR recommendations, with higher scores indicating higher adherence to the guidelines. Odds ratios (ORs) of colorectal cancer were estimated using multiple logistic regression models. Higher adherence to the WCRF/AICR recommendations was associated with a significantly reduced CRC risk (OR 0.67, 95% confidence interval, CI, 0.56-0.80 for a score ≥5 versus cancer (OR 0.67). Inverse associations were observed with the diet-specific WCRF/AICR score (OR 0.71, 95% CI, 0.61-0.84 for ≥3.5 versus <2.5 points) and with specific recommendations on body fatness (OR 0.82, 95% CI, 0.70-0.97), physical activity (OR 0.86, 95% CI, 0.75-1.00), foods and drinks that promote weight gain (OR 0.70, 95% CI, 0.56-0.89), foods of plant origin (OR 0.56, 95% CI, 0.42-0.76), limiting alcohol (OR 0.87, 95% CI, 0.77-0.99) and salt intake (OR 0.63, 95% CI, 0.48-0.84). Our study indicated that adherence to the WCRF/AICR recommendations is inversely related to CRC risk. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Adherence to the World Cancer Research Fund/American Institute for Cancer Research lifestyle recommendations in colorectal cancer survivors : Results of the PROFILES registry

    NARCIS (Netherlands)

    Winkels, Renate M; van Lee, Linde; Beijer, Sandra; Bours, Martijn J; van Duijnhoven, Fränzel J B; Geelen, Anouk; Hoedjes, M.; Mols, F.; de Vries, Jeanne; Weijenberg, Matty P; Kampman, Ellen

    2016-01-01

    We examined adherence to the eight The World Cancer Research Foundation/American Institute for Cancer Research (WCRF/AICR) recommendations on diet, physical activity, and body weight among colorectal cancer survivors, and whether adherence was associated with intention to eat healthy and with the

  7. Selected National Cancer Institute Breast Cancer Research Topics | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... Cancer and Environment Research Centers (BCERCs) to conduct interdisciplinary research on the effects of early environmental exposures ... more than 20 cancers using state-of-the art genomic analysis technologies. Recent findings suggest that there ...

  8. Is concordance with World Cancer Research Fund/American Institute for Cancer Research guidelines for cancer prevention related to subsequent risk of cancer? Results from the EPIC study.

    Science.gov (United States)

    Romaguera, Dora; Vergnaud, Anne-Claire; Peeters, Petra H; van Gils, Carla H; Chan, Doris S M; Ferrari, Pietro; Romieu, Isabelle; Jenab, Mazda; Slimani, Nadia; Clavel-Chapelon, Françoise; Fagherazzi, Guy; Perquier, Florence; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; von Rüsten, Anne; Tjønneland, Anne; Olsen, Anja; Dahm, Christina C; Overvad, Kim; Quirós, José Ramón; Gonzalez, Carlos A; Sánchez, María José; Navarro, Carmen; Barricarte, Aurelio; Dorronsoro, Miren; Khaw, Kay-Tee; Wareham, Nicholas J; Crowe, Francesca L; Key, Timothy J; Trichopoulou, Antonia; Lagiou, Pagona; Bamia, Christina; Masala, Giovanna; Vineis, Paolo; Tumino, Rosario; Sieri, Sabina; Panico, Salvatore; May, Anne M; Bueno-de-Mesquita, H Bas; Büchner, Frederike L; Wirfält, Elisabet; Manjer, Jonas; Johansson, Ingegerd; Hallmans, Göran; Skeie, Guri; Benjaminsen Borch, Kristin; Parr, Christine L; Riboli, Elio; Norat, Teresa

    2012-07-01

    In 2007 the World Cancer Research Fund (WCRF) and the American Institute of Cancer Research (AICR) issued 8 recommendations (plus 2 special recommendations) on diet, physical activity, and weight management for cancer prevention on the basis of the most comprehensive collection of available evidence. We aimed to investigate whether concordance with the WCRF/AICR recommendations was related to cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The present study included 386,355 EPIC participants from 9 European countries. At recruitment, dietary, anthropometric, and lifestyle information was collected. A score was constructed based on the WCRF/AICR recommendations on weight management, physical activity, foods and drinks that promote weight gain, plant foods, animal foods, alcoholic drinks, and breastfeeding for women; the score range was 0-6 for men and 0-7 for women. Higher scores indicated greater concordance with WCRF/AICR recommendations. The association between the score and cancer risk was estimated by using multivariable Cox regression models. Concordance with the score was significantly associated with decreased risk of cancer. A 1-point increment in the score was associated with a risk reduction of 5% (95% CI: 3%, 7%) for total cancer, 12% (95% CI: 9%, 16%) for colorectal cancer, and 16% (95% CI: 9%, 22%) for stomach cancer. Significant associations were also observed for cancers of the breast, endometrium, lung, kidney, upper aerodigestive tract, liver, and esophagus but not for prostate, ovarian, pancreatic, and bladder cancers. Adherence to the WCRF/AICR recommendations for cancer prevention may lower the risk of developing most types of cancer.

  9. Types of Cancer Research

    Science.gov (United States)

    An infographic from the National Cancer Institute (NCI) describing the four broad categories of cancer research: basic research, clinical research, population-based research, and translational research.

  10. Investments in cancer research awarded to UK institutions and the global burden of cancer 2000–2013: a systematic analysis

    Science.gov (United States)

    Maruthappu, Mahiben; Head, Michael G; Zhou, Charlie D; Gilbert, Barnabas J; El-Harasis, Majd A; Raine, Rosalind; Fitchett, Joseph R; Atun, Rifat

    2017-01-01

    Objectives To systematically categorise cancer research investment awarded to United Kingdom (UK) institutions in the period 2000–2013 and to estimate research investment relative to disease burden as measured by mortality, disability-adjusted life years (DALYs) and years lived with disability (YLDs). Design Systematic analysis of all open-access data. Setting and participants Public and philanthropic funding to all UK cancer research institutions, 2000–2013. Main outcome measures Number and financial value of cancer research investments reported in 2013 UK pounds (UK£). Mortality, DALYs and YLDs data were acquired from the Global Burden of Disease Study. A compound metric was adapted to estimate research investment relative to disease burden as measured by mortality, DALYs and YLDs. Results We identified 4299 funded studies with a total research investment of £2.4 billion. The highest fundings by anatomical sites were haematological, breast, prostate, colorectal and ovarian cancers. Relative to disease burden as determined by a compound metric combining mortality, DALYs and YLDs, gender-specific cancers were found to be highest funded—the five sites that received the most funding were prostate, ovarian, breast, mesothelioma and testicular cancer; the least well-funded sites were liver, thyroid, lung, upper gastrointestinal (GI) and bladder. Preclinical science accounted for 66.2% of award numbers and 62.2% of all funding. The top five areas of primary research focus by funding were pathogenesis, drug therapy, diagnostic, screening and monitoring, women's health and immunology. The largest individual funder was the Medical Research Council. In combination, the five lowest funded site-specific cancers relative to disease burden account for 47.9%, 44.3% and 20.4% of worldwide cancer mortality, DALYs and YLDs. Conclusions Research funding for cancer is not allocated according to relative disease burden. These findings are in line with earlier published studies

  11. Some radiation protection problems in a cancer hospital and associated research institute

    International Nuclear Information System (INIS)

    Trott, N.G.; Anderson, W.; Davis, R.P.; Carden, D.M.

    1980-01-01

    Experience gained at the Royal Marsden Hospital and Institute of Cancer Research has shown that with attention to the design of facilities and procedures and an active personnel monitoring policy, relatively large scale radiation commitments can proceed with individual whole body doses to staff being held well below 15 mSv/annum. In spite of detailed attention to control of radiation work, traumatic radiation incidents may still occur. (H.K.)

  12. Retrospective study on risk habits among oral cancer patients in Karnataka Cancer Therapy and Research Institute, Hubli, India.

    Science.gov (United States)

    Aruna, D S; Prasad, K V V; Shavi, Girish R; Ariga, Jitendra; Rajesh, G; Krishna, Madhusudan

    2011-01-01

    Retrospective studies on oral cancer patient profiles related to risk habits could provide etiologic clues for prevention in specific geographic areas. To study risk habit characteristics of oral cancer patients. A cross sectional retrospective case record study of oral cancer patients who reported during 1991-2000 to Karnataka Cancer Therapy and Research Institute, Hubli, India was conducted. Data on socio-demography, histopathology, site of cancer and risk habit profiles of the patients were recorded in a predesigned Performa by one calibrated examiner with internal validity checks. The 1,472 oral cancer patients constituted 11% of total cancer patients. Mean age of the patients was 55 years, ranging from 12-88, with a male: female ratio of 2:1. 1,110 (75%) oral cancer patients had risk habits, 55% were habituated for >10 years and 25% were habit free. 751(51%) patients had individual and 359(24%) had combined risk habits. Majority 59% were chewers of betel quid alone (17%)/betel quid with tobacco (42%); smokers were (31%) and alcohol users were (14%) of patients. Chewers of gutkha, khaini were more in 40 years. Risk habituates were highest (87%) in patients with cancer of buccal mucosa, commonly affected site attributed to chewing habit in (51%) of patients. The prevalence of oral cancer was higher among elderly males predominantly with risk habits of betel quid/tobacco chewing and smoking for more than 10 years.

  13. Institutional Scientific Review of Cancer Clinical Research Protocols: A Unique Requirement That Affects Activation Timelines.

    Science.gov (United States)

    Ning, Ning; Yan, Jingsheng; Dietrich, Martin F; Xie, Xian-Jin; Gerber, David E

    2017-12-01

    The National Cancer Institute (NCI) requirement that clinical trials at NCI-designated cancer centers undergo institutional scientific review in addition to institutional review board evaluation is unique among medical specialties. We sought to evaluate the effect of this process on protocol activation timelines. We analyzed oncology clinical trials that underwent full board review by the Harold C. Simmons Comprehensive Cancer Center Protocol Review and Monitoring Committee (PRMC) from January 1, 2009, through June 30, 2013. We analyzed associations between trial characteristics, PRMC decisions, protocol modifications, and process timelines using the χ 2 test, Fisher's exact test, Wilcoxon rank sum test, Kruskal-Wallis test, and logistic regression. A total of 226 trials were analyzed. Of these, 77% were industry sponsored and 23% were investigator initiated. The median time from submission to PRMC approval was 55 days. The length of review was associated with trial phase, timing of approval, and number of committee changes/clarifications requested. The median process time was 35 days for those approved at first decision, 68 days for second decision, and 116 days for third decision ( P institutional scientific review of oncology clinical trials contributes substantially to protocol activation timelines. Further evaluation of this process and the value added to research quality is warranted.

  14. Investments in cancer research awarded to UK institutions and the global burden of cancer 2000-2013: a systematic analysis.

    Science.gov (United States)

    Maruthappu, Mahiben; Head, Michael G; Zhou, Charlie D; Gilbert, Barnabas J; El-Harasis, Majd A; Raine, Rosalind; Fitchett, Joseph R; Atun, Rifat

    2017-04-20

    To systematically categorise cancer research investment awarded to United Kingdom (UK) institutions in the period 2000-2013 and to estimate research investment relative to disease burden as measured by mortality, disability-adjusted life years (DALYs) and years lived with disability (YLDs). Systematic analysis of all open-access data. Public and philanthropic funding to all UK cancer research institutions, 2000-2013. Number and financial value of cancer research investments reported in 2013 UK pounds (UK£). Mortality, DALYs and YLDs data were acquired from the Global Burden of Disease Study. A compound metric was adapted to estimate research investment relative to disease burden as measured by mortality, DALYs and YLDs. We identified 4299 funded studies with a total research investment of £2.4 billion. The highest fundings by anatomical sites were haematological, breast, prostate, colorectal and ovarian cancers. Relative to disease burden as determined by a compound metric combining mortality, DALYs and YLDs, gender-specific cancers were found to be highest funded-the five sites that received the most funding were prostate, ovarian, breast, mesothelioma and testicular cancer; the least well-funded sites were liver, thyroid, lung, upper gastrointestinal (GI) and bladder. Preclinical science accounted for 66.2% of award numbers and 62.2% of all funding. The top five areas of primary research focus by funding were pathogenesis, drug therapy, diagnostic, screening and monitoring, women's health and immunology. The largest individual funder was the Medical Research Council. In combination, the five lowest funded site-specific cancers relative to disease burden account for 47.9%, 44.3% and 20.4% of worldwide cancer mortality, DALYs and YLDs. Research funding for cancer is not allocated according to relative disease burden. These findings are in line with earlier published studies. Funding agencies and industry should openly document their research investments to

  15. CPTAC Establishes Formal Relationships with Two Academic Institutions in Taiwan | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium (CPTAC) has entered into memorandum of understandings (MOUs) with Chang Gung University and Academia Sinica, in Taipei, Taiwan.

  16. Adherence to the cancer prevention recommendations of the World Cancer Research Fund/American Institute for Cancer Research and mortality: a census-linked cohort.

    Science.gov (United States)

    Lohse, Tina; Faeh, David; Bopp, Matthias; Rohrmann, Sabine

    2016-09-01

    Modifiable lifestyle factors linked to cancer offer great potential for prevention. Previous studies suggest an association between adherence to recommendations on healthy lifestyle and cancer mortality. The aim of this study was to examine whether adherence to the cancer prevention recommendations of the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) is associated with reduced all-cause, total cancer, and specific cancer type mortality. We built a lifestyle score that included 3 categories, based on the recommendations of the WCRF/AICR. Applying Cox regression models, we investigated the association with all-cause, total cancer, and specific cancer type mortality; in addition, we included cardiovascular disease (CVD) mortality. We used census- and death registry-linked survey data allowing a mortality follow-up for ≤32 y. Our analysis included 16,722 participants. Information on lifestyle score components and confounders was collected at baseline. Over a mean follow-up of 21.7 y, 3730 deaths were observed (1332 cancer deaths). Comparing best with poorest category of the lifestyle score showed an inverse association with all-cause (HR: 0.82; 95% CI: 0.75, 0.89) and total cancer (men only, HR: 0.69; 95% CI: 0.57, 0.84) mortality. We estimated that ∼13% of premature cancer deaths in men would have been preventable if lifestyle score levels had been high. Inverse associations were observed for lung, upper aerodigestive tract, stomach, and prostate cancer mortality [men and women combined, HR: 0.72; 95% CI: 0.51, 0.99; HR: 0.49; 95% CI: 0.26, 0.92; HR: 0.34; 95% CI: 0.14, 0.83; HR: 0.48; 95% CI: 0.28, 0.82 (men only), respectively]. CVD mortality was not associated with the lifestyle score (men and women combined, HR: 0.96; 95% CI: 0.82, 1.13). Our results support the importance of adhering to recommendations for a healthy lifestyle with regard to all-cause and cancer mortality. To reduce the burden of cancer in the

  17. Lower Breast Cancer Risk among Women following the World Cancer Research Fund and American Institute for Cancer Research Lifestyle Recommendations: EpiGEICAM Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Adela Castelló

    Full Text Available According to the "World Cancer Research Fund" and the "American Institute of Cancer Research" (WCRF/AICR one in four cancer cases could be prevented through a healthy diet, weight control and physical activity.To explore the association between the WCRF/AICR recommendations and risk of breast cancer.During the period 2006 to 2011 we recruited 973 incident cases of breast cancer and 973 controls from 17 Spanish Regions. We constructed a score based on 9 of the WCRF/AICR recommendations for cancer prevention:: 1Maintain adequate body weight; 2Be physically active; 3Limit the intake of high density foods; 4Eat mostly plant foods; 5Limit the intake of animal foods; 6Limit alcohol intake; 7Limit salt and salt preserved food intake; 8Meet nutritional needs through diet; S1Breastfeed infants exclusively up to 6 months. We explored its association with BC by menopausal status and by intrinsic tumor subtypes (ER+/PR+ & HER2-; HER2+; ER&PR-&HER2- using conditional and multinomial logistic models respectively.Our results point to a linear association between the degree of noncompliance and breast cancer risk. Taking women who met 6 or more recommendations as reference, those meeting less than 3 showed a three-fold excess risk (OR=2.98(CI95%:1.59-5.59, especially for postmenopausal women (OR=3.60(CI95%:1.24;10.47 and ER+/PR+&HER2- (OR=3.60(CI95%:1.84;7.05 and HER2+ (OR=4.23(CI95%:1.66;10.78 tumors. Noncompliance of recommendations regarding the consumption of foods and drinks that promote weight gain in premenopausal women (OR=2.24(CI95%:1.18;4.28; p for interaction=0.014 and triple negative tumors (OR=2.93(CI95%:1.12-7.63; the intake of plant foods in postmenopausal women (OR=2.35(CI95%:1.24;4.44 and triple negative tumors (OR=3.48(CI95%:1.46-8.31; and the alcohol consumption in ER+/PR+&HER2- tumors (OR=1.52 (CI95%:1.06-2.19 showed the strongest associations.Breast cancer prevention might be possible by following the "World Cancer Research Fund" and the

  18. Cancer Research

    Science.gov (United States)

    NCI is the nation's leader in cancer research. Learn more about NCI's cancer research areas, key initiatives, progress made in cancer research, and resources for researchers like research tools, specimens and data.

  19. National Cancer Institute's leadership role in promoting State and Community Tobacco Control research.

    Science.gov (United States)

    Ginexi, Elizabeth M; Vollinger, Robert E

    2016-10-01

    The National Cancer Institute (NCI) has been at the vanguard of funding tobacco control research for decades with major efforts such as the Community Intervention Trial for Smoking Cessation (COMMIT) in 1988 and the American Stop Smoking Intervention Study (ASSIST) in 1991, followed by the Tobacco Research Initiative for State and Community Interventions in 1999. Most recently, in 2011, the NCI launched the State and Community Tobacco Control (SCTC) Research Initiative to address gaps in secondhand smoke policies, tax and pricing policies, mass media countermeasures, community and social norms and tobacco marketing. The initiative supported large scale research projects and time-sensitive ancillary pilot studies in response to expressed needs of state and community partners. This special issue of Tobacco Control showcases exciting findings from the SCTC. In this introductory article, we provide a brief account of NCI's historical commitment to promoting research to inform tobacco control policy. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  20. Science, institutional archives and open access: an overview and a pilot survey on the Italian cancer research institutions.

    Science.gov (United States)

    Poltronieri, Elisabetta; Truccolo, Ivana; Di Benedetto, Corrado; Castelli, Mauro; Mazzocut, Mauro; Cognetti, Gaetana

    2010-12-20

    The Open Archive Initiative (OAI) refers to a movement started around the '90 s to guarantee free access to scientific information by removing the barriers to research results, especially those related to the ever increasing journal subscription prices. This new paradigm has reshaped the scholarly communication system and is closely connected to the build up of institutional repositories (IRs) conceived to the benefit of scientists and research bodies as a means to keep possession of their own literary production. The IRs are high-value tools which permit authors to gain visibility by enabling rapid access to scientific material (not only publications) thus increasing impact (citation rate) and permitting a multidimensional assessment of research findings. A survey was conducted in March 2010 to mainly explore the managing system in use for archiving the research finding adopted by the Italian Scientific Institutes for Research, Hospitalization and Health Care (IRCCS) of the oncology area within the Italian National Health Service (Servizio Sanitario Nazionale, SSN). They were asked to respond to a questionnaire intended to collect data about institutional archives, metadata formats and posting of full-text documents. The enquiry concerned also the perceived role of the institutional repository DSpace ISS, built up by the Istituto Superiore di Sanità (ISS) and based on a XML scheme for encoding metadata. Such a repository aims at acting as a unique reference point for the biomedical information produced by the Italian research institutions. An in-depth analysis has also been performed on the collection of information material addressed to patients produced by the institutions surveyed. The survey respondents were 6 out of 9. The results reveal the use of different practices and standard among the institutions concerning: the type of documentation collected, the software adopted, the use and format of metadata and the conditions of accessibility to the IRs. The

  1. Science, institutional archives and open access: an overview and a pilot survey on the Italian cancer research institutions

    Directory of Open Access Journals (Sweden)

    Mazzocut Mauro

    2010-12-01

    Full Text Available Abstract Background The Open Archive Initiative (OAI refers to a movement started around the '90s to guarantee free access to scientific information by removing the barriers to research results, especially those related to the ever increasing journal subscription prices. This new paradigm has reshaped the scholarly communication system and is closely connected to the build up of institutional repositories (IRs conceived to the benefit of scientists and research bodies as a means to keep possession of their own literary production. The IRs are high-value tools which permit authors to gain visibility by enabling rapid access to scientific material (not only publications thus increasing impact (citation rate and permitting a multidimensional assessment of research findings. Methods A survey was conducted in March 2010 to mainly explore the managing system in use for archiving the research finding adopted by the Italian Scientific Institutes for Research, Hospitalization and Health Care (IRCCS of the oncology area within the Italian National Health Service (Servizio Sanitario Nazionale, SSN. They were asked to respond to a questionnaire intended to collect data about institutional archives, metadata formats and posting of full-text documents. The enquiry concerned also the perceived role of the institutional repository DSpace ISS, built up by the Istituto Superiore di Sanità (ISS and based on a XML scheme for encoding metadata. Such a repository aims at acting as a unique reference point for the biomedical information produced by the Italian research institutions. An in-depth analysis has also been performed on the collection of information material addressed to patients produced by the institutions surveyed. Results The survey respondents were 6 out of 9. The results reveal the use of different practices and standard among the institutions concerning: the type of documentation collected, the software adopted, the use and format of metadata and the

  2. Critical appraisal of the suitability of translational research models for performance assessment of cancer institutions

    NARCIS (Netherlands)

    Rajan, A.; Sullivan, R.; Bakker, S.; van Harten, Willem H.

    2012-01-01

    Background. Translational research is a complex cumulative process that takes time. However, the operating environment for cancer centers engaged in translational research is now financially insecure. Centers are challenged to improve results and reduce time from discovery to practice innovations.

  3. Proceedings of the 3rd Annual Albert Institute for Bladder Cancer Research Symposium.

    Science.gov (United States)

    Flaig, Thomas W; Kamat, Ashish M; Hansel, Donna; Ingersoll, Molly A; Barton Grossman, H; Mendelsohn, Cathy; DeGraff, David; Liao, Joseph C; Taylor, John A

    2017-07-27

    The Third Annual Albert Institute Bladder Symposium was held on September 8-10th, 2016, in Denver Colorado. Participants discussed several critical topics in the field of bladder cancer: 1) Best practices for tissue analysis and use to optimize correlative studies, 2) Modeling bladder cancer to facilitate understanding and innovation, 3) Targeted therapies for bladder cancer, 4) Tumor phylogeny in bladder cancer, 5) New Innovations in bladder cancer diagnostics. Our understanding of and approach to treating urothelial carcinoma is undergoing rapid advancement. Preclinical models of bladder cancer have been leveraged to increase our basic and mechanistic understanding of the disease. With the approval of immune checkpoint inhibitors for the treatment of advanced urothelial carcinoma, the treatment approach for these patients has quickly changed. In this light, molecularly-defined subtypes of bladder cancer and appropriate pre-clinical models are now essential to the further advancement and appropriate application of these therapeutic improvements. The optimal collection and processing of clinical urothelial carcinoma tissues samples will also be critical in the development of predictive biomarkers for therapeutic selection. Technological advances in other areas including optimal imaging technologies and micro/nanotechnologies are being applied to bladder cancer, especially in the localized setting, and hold the potential for translational impact in the treatment of bladder cancer patients. Taken together, advances in several basic science and clinical areas are now converging in bladder cancer. These developments hold the promise of shaping and improving the clinical care of those with the disease.

  4. National Cancer Institute and American Association for Clinical Chemistry Partner to Bridge the Gap | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The National Cancer Institute, through its Clinical Proteomic Technologies for Cancer (CPTC) initiative has entered into a memorandum of understanding with the American Association for Clinical Chemistry (AACC) to join forces to promote and educate the clinical chemistry community in the area of proteomic standards and technology advances.

  5. CPRIT/Johnson Space Center, September, 2011 (Cancer Prevention and Research Institute of Texas)

    Science.gov (United States)

    Davis, Jeffrey; Lane, Helen; Baker, Tracey; Cucinotta, Francis; Wu, Honglu

    2011-01-01

    JSC researchers study carcinogenesis, cancer prevention and treatment along with epidemiological (primarily retrospective and longitudinal) studies, modeling, and interactions with the environment such as radiation, nutritional, and endocrine changes related to space flight along with behaviors such as smoking. Cancer research is a major focus for human space flight due to the exposure to space radiation which consists of particles of varying charges and energies, and secondary neutrons. The JSC laboratories collaborate with investigators from the U.S. as well as our European and Japanese partners. We use accelerator facilities at the Brookhaven National Laboratory, Loma Linda University and Los Alamos National Laboratory that generate high energy charged particles and neutrons to simulate cosmic radiation and solar particle events. The research using cultured cells and animals concentrates on damage and repair from the level of DNA to organ tissues, due to exposure to simulated space radiation exposure, that contribute to the induction of leukemia and solid tumors in most major tissues such as lung, colon, liver and breast. The goal of the research is to develop a mathematical model that can predict cancer morbidity and mortality risks with sufficient accuracy for a given space mission.

  6. Racial Differences in Information Needs During and After Cancer Treatment: a Nationwide, Longitudinal Survey by the University of Rochester Cancer Center National Cancer Institute Community Oncology Research Program.

    Science.gov (United States)

    Asare, Matthew; Peppone, Luke J; Roscoe, Joseph A; Kleckner, Ian R; Mustian, Karen M; Heckler, Charles E; Guido, Joseph J; Sborov, Mark; Bushunow, Peter; Onitilo, Adedayo; Kamen, Charles

    2018-02-01

    Before treatment, cancer patients need information about side effects and prognosis, while after treatment they need information to transition to survivorship. Research documenting these needs is limited, especially among racial and ethnic minorities. This study evaluated cancer patients' needs according to race both before and after treatment. We compared white (n = 904) to black (n = 52) patients receiving treatment at 17 National Cancer Institute Community Oncology Research Program (NCORP) sites on their cancer-related concerns and need for information before and after cancer treatment. Two-sample t test and chi-squared analyses were used to assess group differences. Compared to white patients, black patients reported significantly higher concerns about diet (44.3 vs. 25.4 %,) and exercise (40.4 vs. 19.7 %,) during the course of treatment. Compared to whites, blacks also had significantly higher concern about treatment-related issues (white vs. black mean, 25.52 vs. 31.78), self-image issues (7.03 vs. 8.60), family-related issues (10.44 vs. 12.84), and financial concerns (6.42 vs. 8.90, all p information needs regarding follow-up tests (8.17 vs. 9.44), stress management (4.12 vs. 4.89), and handling stigma after cancer treatment (4.21 vs. 4.89) [all p information needs differed by race, with black patients reporting greater information needs and concerns. In clinical practice, tailored approaches may work particularly well in addressing the needs and concerns of black patients.

  7. Radiogenomics of High-Grade Serous Ovarian Cancer: Multireader Multi-Institutional Study from the Cancer Genome Atlas Ovarian Cancer Imaging Research Group.

    Science.gov (United States)

    Vargas, Hebert Alberto; Huang, Erich P; Lakhman, Yulia; Ippolito, Joseph E; Bhosale, Priya; Mellnick, Vincent; Shinagare, Atul B; Anello, Maria; Kirby, Justin; Fevrier-Sullivan, Brenda; Freymann, John; Jaffe, C Carl; Sala, Evis

    2017-11-01

    Purpose To evaluate interradiologist agreement on assessments of computed tomography (CT) imaging features of high-grade serous ovarian cancer (HGSOC), to assess their associations with time-to-disease progression (TTP) and HGSOC transcriptomic profiles (Classification of Ovarian Cancer [CLOVAR]), and to develop an imaging-based risk score system to predict TTP and CLOVAR profiles. Materials and Methods This study was a multireader, multi-institutional, institutional review board-approved, HIPAA-compliant retrospective analysis of 92 patients with HGSOC (median age, 61 years) with abdominopelvic CT before primary cytoreductive surgery available through the Cancer Imaging Archive. Eight radiologists from the Cancer Genome Atlas Ovarian Cancer Imaging Research Group developed and independently recorded the following CT features: characteristics of primary ovarian mass(es), presence of definable mesenteric implants and infiltration, presence of other implants, presence and distribution of peritoneal spread, presence and size of pleural effusions and ascites, lymphadenopathy, and distant metastases. Interobserver agreement for CT features was assessed, as were univariate and multivariate associations with TTP and CLOVAR mesenchymal profile (worst prognosis). Results Interobserver agreement for some features was strong (eg, α = .78 for pleural effusion and ascites) but was lower for others (eg, α = .08 for intraparenchymal splenic metastases). Presence of peritoneal disease in the right upper quadrant (P = .0003), supradiaphragmatic lymphadenopathy (P = .0004), more peritoneal disease sites (P = .0006), and nonvisualization of a discrete ovarian mass (P = .0037) were associated with shorter TTP. More peritoneal disease sites (P = .0025) and presence of pouch of Douglas implants (P = .0045) were associated with CLOVAR mesenchymal profile. Combinations of imaging features contained predictive signal for TTP (concordance index = 0.658; P = .0006) and CLOVAR profile (mean

  8. 75 FR 79010 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-12-17

    ... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings... Cancer Institute Special Emphasis Panel. Development of Devices for Point of Care Analysis of Circulating... Biology Research; 93.397, Cancer Centers Support; 93.398, Cancer Research Manpower; 93.399, Cancer Control...

  9. 75 FR 5092 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-02-01

    ... . Name of Committee: National Cancer Institute Special Emphasis Panel, Quantitative Cell-Based Imaging....396, Cancer Biology Research; 93.397, Cancer Centers Support; 93.398, Cancer Research Manpower; 93.399... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute...

  10. Translational Genomics Research Institute: Quantified Cancer Cell Line Encyclopedia (CCLE) RNA-seq Data | Office of Cancer Genomics

    Science.gov (United States)

    Many applications analyze quantified transcript-level abundances to make inferences.  Having completed this computation across the large sample set, the CTD2 Center at the Translational Genomics Research Institute presents the quantified data in a straightforward, consolidated form for these types of analyses.   Experimental Approaches  

  11. Homogeneous group, research, institution

    Directory of Open Access Journals (Sweden)

    Francesca Natascia Vasta

    2014-09-01

    Full Text Available The work outlines the complex connection among empiric research, therapeutic programs and host institution. It is considered the current research state in Italy. Italian research field is analyzed and critic data are outlined: lack of results regarding both the therapeutic processes and the effectiveness of eating disorders group analytic treatment. The work investigates on an eating disorders homogeneous group, led into an eating disorder outpatient service. First we present the methodological steps the research is based on including the strong connection among theory and clinical tools. Secondly clinical tools are described and the results commented. Finally, our results suggest the necessity of validating some more specifical hypothesis: verifying the relationship between clinical improvement (sense of exclusion and painful emotions reduction and specific group therapeutic processes; verifying the relationship between depressive feelings, relapses and transition trough a more differentiated groupal field.Keywords: Homogeneous group; Eating disorders; Institutional field; Therapeutic outcome

  12. 76 FR 16431 - National Cancer Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-03-23

    ... Committee: National Cancer Institute Special Emphasis Panel; SPORE in Lymphoma, Breast, Ovarian... and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meeting...

  13. National Cancer Institute News

    Science.gov (United States)

    ... with Cancer Feelings and Cancer Adjusting to Cancer Self-Image & Sexuality Day-to-Day Life Support for Caregivers ... Alternative Medicine Coping Feelings & Cancer Adjusting to Cancer Self Image & Sexuality Day to Day Life Survivorship Support for ...

  14. 78 FR 27408 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-10

    ... Methods for the Detection of Cancer Recurrence in Post-Therapy Breast Cancer Patients. Date: June 4, 2013... Prevention Research; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings...

  15. Operationalization of community-based participatory research principles: assessment of the national cancer institute's community network programs.

    Science.gov (United States)

    Braun, Kathryn L; Nguyen, Tung T; Tanjasiri, Sora Park; Campbell, Janis; Heiney, Sue P; Brandt, Heather M; Smith, Selina A; Blumenthal, Daniel S; Hargreaves, Margaret; Coe, Kathryn; Ma, Grace X; Kenerson, Donna; Patel, Kushal; Tsark, JoAnn; Hébert, James R

    2012-06-01

    We examined how National Cancer Institute-funded Community Network Programs (CNPs) operationalized principles of community-based participatory research (CBPR). We reviewed the literature and extant CBPR measurement tools. On the basis of that review, we developed a 27-item questionnaire for CNPs to self-assess their operationalization of 9 CBPR principles. Our team comprised representatives of 9 of the National Cancer Institute's 25 CNPs. Of the 25 CNPs, 22 (88%) completed the questionnaire. Most scored well on CBPR principles of recognizing community as a unit of identity, building on community strengths, facilitating colearning, embracing iterative processes in developing community capacity, and achieving a balance between data generation and intervention. CNPs varied in the extent to which they employed CBPR principles of addressing determinants of health, sharing power among partners, engaging the community in research dissemination, and striving for sustainability. Although the development of assessment tools in this field is in its infancy, our findings suggest that fidelity to CBPR processes can be assessed in a variety of settings.

  16. 77 FR 24969 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-04-26

    ... . Name of Committee: National Cancer Institute Special Emphasis Panel; SPORE in Breast, Prostate and... Construction; 93.393, Cancer Cause and Prevention Research; 93.394, Cancer Detection and Diagnosis Research; 93... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings...

  17. 75 FR 14172 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-03-24

    ... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings... Emphasis Panel, Nucleic Acid Analysis for the Molecular Characterization of Cancer. Date: April 6, 2010... Biology Research; 93.397, Cancer Centers Support; 93.398, Cancer Research Manpower; 93.399, Cancer Control...

  18. 75 FR 21002 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-04-22

    ... Panel, SPORE in Lymphoma and Breast Cancer. Date: June 15-16, 2010. Time: 5 p.m. to 5 p.m. Agenda: To...; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings...

  19. 75 FR 3239 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-20

    ... Special Emphasis Panel, Basal-like Breast Cancer Assay. Date: March 10, 2010. Time: 8 a.m. to 7 p.m..., Cancer Cause and Prevention Research; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings...

  20. 76 FR 52960 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-24

    ... Emphasis Panel, Mechanisms of Cell Signaling in Cancer. Date: October 13-14, 2011. Time: 3 to 5 p.m. Agenda..., Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers Support; 93.398... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute...

  1. Training the Cancer Research Workforce

    Science.gov (United States)

    The National Cancer Institute (NCI) builds up the nation's cancer research workforce through training and career development grants, as well as intramural research experiences at the NIH Clinical Center and NCI offices and laboratories in Maryland.

  2. National Human Genome Research Institute

    Science.gov (United States)

    ... the Director Organization Reports & Publications Español The National Human Genome Research Institute conducts genetic and genomic research, funds ... genomic literacy among physicians. Funded by the National Human Genome Research Institute (NHGRI), The Universal Genomics Instructor Handbook ...

  3. 78 FR 55750 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-11

    ... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings... Innovative Molecular Analysis Technology Development for Cancer Research (R21). Date: October 24, 2013. Time...: National Cancer Institute Special Emphasis Panel; Integrative Cancer Biology. Date: October 29, 2013. Time...

  4. Adherence to the World Cancer Research Fund/American Institute for Cancer Research Guideline Is Associated With Better Health-Related Quality of Life Among Chinese Patients With Breast Cancer.

    Science.gov (United States)

    Lei, Yuan-Yuan; Ho, Suzanne C; Cheng, Ashley; Kwok, Carol; Lee, Chi-Kiu Iris; Cheung, Ka Li; Lee, Roselle; Loong, Herbert H F; He, Yi-Qian; Yeo, Winnie

    2018-03-01

    Background: The 2007 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) guideline provides recommendations for cancer prevention among cancer survivors. Limited data have examined whether guideline adherence is related to health-related quality of life (HRQoL) among Chinese patients with breast cancer. Methods: An ongoing prospective cohort study involving 1,462 Chinese women with early-stage breast cancer assessed exercise, diet, and body mass index (BMI) at baseline and at 18-months follow-up after diagnosis. Each assessment recorded patient habits within the previous 12 months. HRQoL was evaluated by the EORTC Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30). We first compared the level of adherence to WCRF/AICR recommendations before and after cancer diagnosis. We then examined whether adherence to these recommendations after diagnosis was associated with HRQoL at 18 months. Results: The mean adherence score significantly increased from baseline (3.2; SD, 1.1) to 18-month follow-up (3.9; SD, 1.1; P <.001). Overall, increasing adherence to the WCRF/AICR guideline was associated with higher scores of global health status/quality of life (QoL; P trend =.011), physical ( P trend <.001) and role functioning ( P trend =.024), and lower scores for fatigue ( P trend =.016), nausea and vomiting ( P trend <.001), pain ( P trend =.004), dyspnea ( P trend =.030), loss of appetite ( P trend =.007), and diarrhea ( P trend =.020). Patients with cancer who met the BMI recommendation had higher scores for physical functioning ( P =.001) and lower scores for fatigue ( P =.024), pain ( P <.001), and dyspnea ( P =.045). Adherence to physical activity recommendation was associated with better scores of global health status/QoL ( P <.001), physical functioning ( P =.003), fatigue ( P =.002), pain ( P =.018), and dyspnea ( P =.021). Higher adherence to diet recommendation was associated with lower scores of nausea and vomiting ( P trend =.005), loss of

  5. A Novel Cross-Disciplinary Multi-Institute Approach to Translational Cancer Research: Lessons Learned from Pennsylvania Cancer Alliance Bioinformatics Consortium (PCABC

    Directory of Open Access Journals (Sweden)

    Ashokkumar A. Patel

    2007-01-01

    Full Text Available Background: The Pennsylvania Cancer Alliance Bioinformatics Consortium (PCABC, http://www.pcabc.upmc.edu is one of the first major project-based initiatives stemming from the Pennsylvania Cancer Alliance that was funded for four years by the Department of Health of the Commonwealth of Pennsylvania. The objective of this was to initiate a prototype biorepository and bioinformatics infrastructure with a robust data warehouse by developing a statewide data model (1 for bioinformatics and a repository of serum and tissue samples; (2 a data model for biomarker data storage; and (3 a public access website for disseminating research results and bioinformatics tools. The members of the Consortium cooperate closely, exploring the opportunity for sharing clinical, genomic and other bioinformatics data on patient samples in oncology, for the purpose of developing collaborative research programs across cancer research institutions in Pennsylvania. The Consortium’s intention was to establish a virtual repository of many clinical specimens residing in various centers across the state, in order to make them available for research. One of our primary goals was to facilitate the identification of cancer specific biomarkers and encourage collaborative research efforts among the participating centers.Methods: The PCABC has developed unique partnerships so that every region of the state can effectively contribute and participate. It includes over 80 individuals from 14 organizations, and plans to expand to partners outside the State. This has created a network of researchers, clinicians, bioinformaticians, cancer registrars, program directors, and executives from academic and community health systems, as well as external corporate partners - all working together to accomplish a common mission. The various sub-committees have developed a common IRB protocol template, common data elements for standardizing data collections for three organ sites, intellectual

  6. Sustainable patient participation in research; an intervention study at Erasmus MC Cancer Institute

    NARCIS (Netherlands)

    Schölvinck, A.F.M.; Schuitmaker-Warnaar, T.J.; Petit, V.; Broerse, J.E.W.

    2016-01-01

    Background: Patient involvement in research (PI) can provide complementary views on research priorities, as patients possess experiential knowledge about their disease. In order to sustainably embed PI, knowledge on potential facilitators and barriers is needed. In a case study at the Erasmus MC

  7. 76 FR 17930 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-03-31

    ... HUMAN SERVICES National Institutes of Health National Cancer Institute; Notice of Closed Meetings... Special Emphasis Panel; Innovative Emerging Molecular Analysis Technologies. Date: June 2-3, 2011. Time: 8..., Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology...

  8. Security and privacy requirements for a multi-institutional cancer research data grid: an interview-based study

    Directory of Open Access Journals (Sweden)

    Weems William A

    2009-06-01

    Full Text Available Abstract Background Data protection is important for all information systems that deal with human-subjects data. Grid-based systems – such as the cancer Biomedical Informatics Grid (caBIG – seek to develop new mechanisms to facilitate real-time federation of cancer-relevant data sources, including sources protected under a variety of regulatory laws, such as HIPAA and 21CFR11. These systems embody new models for data sharing, and hence pose new challenges to the regulatory community, and to those who would develop or adopt them. These challenges must be understood by both systems developers and system adopters. In this paper, we describe our work collecting policy statements, expectations, and requirements from regulatory decision makers at academic cancer centers in the United States. We use these statements to examine fundamental assumptions regarding data sharing using data federations and grid computing. Methods An interview-based study of key stakeholders from a sample of US cancer centers. Interviews were structured, and used an instrument that was developed for the purpose of this study. The instrument included a set of problem scenarios – difficult policy situations that were derived during a full-day discussion of potentially problematic issues by a set of project participants with diverse expertise. Each problem scenario included a set of open-ended questions that were designed to elucidate stakeholder opinions and concerns. Interviews were transcribed verbatim and used for both qualitative and quantitative analysis. For quantitative analysis, data was aggregated at the individual or institutional unit of analysis, depending on the specific interview question. Results Thirty-one (31 individuals at six cancer centers were contacted to participate. Twenty-four out of thirty-one (24/31 individuals responded to our request- yielding a total response rate of 77%. Respondents included IRB directors and policy-makers, privacy and

  9. Security and privacy requirements for a multi-institutional cancer research data grid: an interview-based study.

    Science.gov (United States)

    Manion, Frank J; Robbins, Robert J; Weems, William A; Crowley, Rebecca S

    2009-06-15

    Data protection is important for all information systems that deal with human-subjects data. Grid-based systems--such as the cancer Biomedical Informatics Grid (caBIG)--seek to develop new mechanisms to facilitate real-time federation of cancer-relevant data sources, including sources protected under a variety of regulatory laws, such as HIPAA and 21CFR11. These systems embody new models for data sharing, and hence pose new challenges to the regulatory community, and to those who would develop or adopt them. These challenges must be understood by both systems developers and system adopters. In this paper, we describe our work collecting policy statements, expectations, and requirements from regulatory decision makers at academic cancer centers in the United States. We use these statements to examine fundamental assumptions regarding data sharing using data federations and grid computing. An interview-based study of key stakeholders from a sample of US cancer centers. Interviews were structured, and used an instrument that was developed for the purpose of this study. The instrument included a set of problem scenarios--difficult policy situations that were derived during a full-day discussion of potentially problematic issues by a set of project participants with diverse expertise. Each problem scenario included a set of open-ended questions that were designed to elucidate stakeholder opinions and concerns. Interviews were transcribed verbatim and used for both qualitative and quantitative analysis. For quantitative analysis, data was aggregated at the individual or institutional unit of analysis, depending on the specific interview question. Thirty-one (31) individuals at six cancer centers were contacted to participate. Twenty-four out of thirty-one (24/31) individuals responded to our request- yielding a total response rate of 77%. Respondents included IRB directors and policy-makers, privacy and security officers, directors of offices of research, information

  10. Security and privacy requirements for a multi-institutional cancer research data grid: an interview-based study

    Science.gov (United States)

    2009-01-01

    Background Data protection is important for all information systems that deal with human-subjects data. Grid-based systems – such as the cancer Biomedical Informatics Grid (caBIG) – seek to develop new mechanisms to facilitate real-time federation of cancer-relevant data sources, including sources protected under a variety of regulatory laws, such as HIPAA and 21CFR11. These systems embody new models for data sharing, and hence pose new challenges to the regulatory community, and to those who would develop or adopt them. These challenges must be understood by both systems developers and system adopters. In this paper, we describe our work collecting policy statements, expectations, and requirements from regulatory decision makers at academic cancer centers in the United States. We use these statements to examine fundamental assumptions regarding data sharing using data federations and grid computing. Methods An interview-based study of key stakeholders from a sample of US cancer centers. Interviews were structured, and used an instrument that was developed for the purpose of this study. The instrument included a set of problem scenarios – difficult policy situations that were derived during a full-day discussion of potentially problematic issues by a set of project participants with diverse expertise. Each problem scenario included a set of open-ended questions that were designed to elucidate stakeholder opinions and concerns. Interviews were transcribed verbatim and used for both qualitative and quantitative analysis. For quantitative analysis, data was aggregated at the individual or institutional unit of analysis, depending on the specific interview question. Results Thirty-one (31) individuals at six cancer centers were contacted to participate. Twenty-four out of thirty-one (24/31) individuals responded to our request- yielding a total response rate of 77%. Respondents included IRB directors and policy-makers, privacy and security officers, directors of

  11. Institutional Support : Ethiopian Development Research Institute ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Ethiopian Development Research Institute (EDRI) was established in 1999 and became operational in 2003 as a semi-autonomous organization accountable to the Office ... Socially equitable climate action is essential to strengthen the resilience of all people, without which we cannot achieve women's empowerment.

  12. Evaluation of institutional cancer registries in Colombia

    Directory of Open Access Journals (Sweden)

    Luis Gabriel Cuervo

    1999-09-01

    Full Text Available The four primary objectives of this descriptive study were to: 1 design a quality-measurement instrument for institutional cancer registries (ICRs, 2 evaluate the existing ICRs in Colombia with the designed instrument, 3 categorize the different registries according to their quality and prioritize efforts that will efficiently promote better registries with the limited resources available, and 4 determine the institution with the greatest likelihood of successfully establishing Colombia's second population-based cancer registry. In 1990 the National Cancer Institute of Colombia developed 13 institution-based cancer registries in different Colombian cities in order to promote the collection of data from a large group of cancer diagnostic and treatment centers. During the first half of 1997, this evaluation reviewed 12 registries; one of the original 13 no longer existed. All of the Colombian institutions (hospitals that maintain institution-based cancer registries were included in the study. At each institution, a brief survey was administered to the hospital director, the registry coordinator, and the registrar (data manager. Researchers investigated the institutions by looking at six domains that are in standard use internationally. Within each domain, questions were developed and selected through the Delphi method. Each domain and each question were assigned weights through a consensus process. In most cases, two interviewers went to each site to collect the information. The university hospitals in Cali, Pereira, and Medellín had substantially higher scores, reflecting a good level of performance. Four of the 12 institutions had almost no cancer registry work going on. Five of the 12 hospital directors considered that the information provided by the cancer registries influenced their administrative decisions. Three of the registries had patient survival data. Four of the institutions allocated specific resources to operate their cancer

  13. Thyroid cancer: experiences of Cancer Institute, Madras

    International Nuclear Information System (INIS)

    Kannan, R. Ravi; Mahajan, V.; Ganesh, M.S.; Ayyappan, S.; Suresh, V.; Suryasen, S.

    1999-01-01

    It has been long recognized that Thyroid Cancer (TC) envelopes under its umbrella a spectrum of cancers from the relatively indolent well differentiated papillary and follicular cancers to the aggressive and rapidly fatal anaplastic cancers. Medullary cancers fall in between the two extremes. Recently, poor prognostic variants of well-differentiated cancers have been described. There is also a move to define a group of poorly differentiated TC including the insular variants distinguishing them from anaplastic carcinomas. Of the 1168 patients with thyroid nodules seen at the Cancer Institute (WIA), Chennai between 1956 and 1996, 670 cases proved to be malignant either cytologically or histologically. This report is based on the follow-up of these patients which at 10 years was 75%

  14. 75 FR 20370 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-04-19

    ... Cancer Institute Special Emphasis Panel, Assay Systems for Drug Efficacy in Cancer Stem Cells. Date..., Rockville, MD 20852. Contact Person: David G. Ransom, PhD, Scientific Review Officer, Research Programs... Domestic Assistance Program Nos. 93.392, Cancer Construction; 93.393, Cancer Cause and Prevention Research...

  15. National Space Biomedical Research Institute

    Science.gov (United States)

    2003-01-01

    In June 1996, NASA released a Cooperative Agreement Notice (CAN) inviting proposals to establish a National Space Biomedical Research Institute (9-CAN-96-01). This CAN stated that: The Mission of the Institute will be to lead a National effort for accomplishing the integrated, critical path, biomedical research necessary to support the long term human presence, development, and exploration of space and to enhance life on Earth by applying the resultant advances in human knowledge and technology acquired through living and working in space. The Institute will be the focal point of NASA sponsored space biomedical research. This statement has not been amended by NASA and remains the mission of the NSBRI.

  16. Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

    Science.gov (United States)

    The Nutritional Science Research Group in the Division of Cancer Prevention at the National Cancer Institute, National Institutes of Health and the Department of Nutrition at the Clinical Center, National Institutes of Health are offering a one week educational opportunity in "Nutrition and Cancer Prevention Research" for individuals with a sustained commitment to nutrition

  17. United States military contributions to the National Cancer Institute.

    Science.gov (United States)

    Sarvis, Jamey A; Thompson, Ian M

    2009-01-01

    To review contributions from the Department of Defense and the United States military to cancer research and the National Cancer Institute. The Department of Defense and the military have a number of programs aimed at cancer research with significant dedication to prostate cancer, such as the Prostate Cancer Research Program and Center for Prostate Disease Research. In addition, the military has significant involvement with the National Cancer Institute (NCI) through the various Cooperative Research Groups. The military has played a critical role in large NCI sponsored multi-institutional clinical trials such as the Prostate Cancer Prevention Trial (PCPT) and the Servicemen's Testicular Tumor Environmental Endocrine Determinants Study (STEED). The Department of Defense has demonstrated a consistent commitment to cancer research.

  18. 76 FR 76981 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-12-09

    ... Cancer Institute Special Emphasis Panel, Nanotechnology Reformulations for Cancer Drugs. Date: April 12... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel, NCI SPORE in Prostate and Gastrointestinal Cancers. Date...

  19. Credit allocation for research institutes

    Science.gov (United States)

    Wang, J.-P.; Guo, Q.; Yang, K.; Han, J.-T.; Liu, J.-G.

    2017-05-01

    It is a challenging work to assess research performance of multiple institutes. Considering that it is unfair to average the credit to the institutes which is in the different order from a paper, in this paper, we present a credit allocation method (CAM) with a weighted order coefficient for multiple institutes. The results for the APS dataset with 18987 institutes show that top-ranked institutes obtained by the CAM method correspond to well-known universities or research labs with high reputation in physics. Moreover, we evaluate the performance of the CAM method when citation links are added or rewired randomly quantified by the Kendall's Tau and Jaccard index. The experimental results indicate that the CAM method has better performance in robustness compared with the total number of citations (TC) method and Shen's method. Finally, we give the first 20 Chinese universities in physics obtained by the CAM method. However, this method is valid for any other branch of sciences, not just for physics. The proposed method also provides universities and policy makers an effective tool to quantify and balance the academic performance of university.

  20. 76 FR 576 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-05

    ... Committee: National Cancer Institute Special Emphasis Panel; Nanotechnology Sensing Platforms. Date: March 2... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel; SPORE in Mesothelioma, Lung, Breast and Ovarian Cancers. Date...

  1. 77 FR 15783 - National Cancer Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-03-16

    ... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel Nanotechnology... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... proposals. Place: National Institutes of Health, National Cancer Institute, 6116 Executive Blvd., Conference...

  2. Workshop on Cancer Research

    International Nuclear Information System (INIS)

    Vermorken, A.; Durieux, L.

    1991-01-01

    On April, 22-24 April 1991, the Hungarian National Institute of Oncology and the Commission of the European Communities have organized a workshop on Cancer Research. The aim of the meeting was to provide the participants information on the ongoing research in Hungary and in Member States. The topic is of importance for Hungary and it was also considered that the meeting could contribute to identify subjects of possible collaboration between Hungarian and Member State laboratories in the case financial support would become available. Three papers about new therapies under development were presented proton therapy and Boron neutron capture therapy

  3. Concordance with World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) guidelines for cancer prevention and obesity-related cancer risk in the Framingham Offspring cohort (1991-2008).

    Science.gov (United States)

    Makarem, Nour; Lin, Yong; Bandera, Elisa V; Jacques, Paul F; Parekh, Niyati

    2015-02-01

    This prospective cohort study evaluates associations between healthful behaviors consistent with WCRF/AICR cancer prevention guidelines and obesity-related cancer risk, as a third of cancers are estimated to be preventable. The study sample consisted of adults from the Framingham Offspring cohort (n = 2,983). From 1991 to 2008, 480 incident doctor-diagnosed obesity-related cancers were identified. Data on diet, measured by a food frequency questionnaire, anthropometric measures, and self-reported physical activity, collected in 1991 was used to construct a 7-component score based on recommendations for body fatness, physical activity, foods that promote weight gain, plant foods, animal foods, alcohol, and food preservation, processing, and preparation. Multivariable Cox regression models were used to estimate associations between the computed score, its components, and subcomponents in relation to obesity-related cancer risk. The overall score was not associated with obesity-related cancer risk after adjusting for age, sex, smoking, energy, and preexisting conditions (HR 0.94, 95 % CI 0.86-1.02). When score components were evaluated separately, for every unit increment in the alcohol score, there was 29 % lower risk of obesity-related cancers (HR 0.71, 95 % CI 0.51-0.99) and 49-71 % reduced risk of breast, prostate, and colorectal cancers. Every unit increment in the subcomponent score for non-starchy plant foods (fruits, vegetables, and legumes) among participants who consume starchy vegetables was associated with 66 % reduced risk of colorectal cancer (HR 0.44, 95 % CI 0.22-0.88). Lower alcohol consumption and a plant-based diet consistent with the cancer prevention guidelines were associated with reduced risk of obesity-related cancers in this population.

  4. A method for analyzing the business case for provider participation in the National Cancer Institute's Community Clinical Oncology Program and similar federally funded, provider-based research networks.

    Science.gov (United States)

    Reiter, Kristin L; Song, Paula H; Minasian, Lori; Good, Marjorie; Weiner, Bryan J; McAlearney, Ann Scheck

    2012-09-01

    The Community Clinical Oncology Program (CCOP) plays an essential role in the efforts of the National Cancer Institute (NCI) to increase enrollment in clinical trials. Currently, there is little practical guidance in the literature to assist provider organizations in analyzing the return on investment (ROI), or business case, for establishing and operating a provider-based research network (PBRN) such as the CCOP. In this article, the authors present a conceptual model of the business case for PBRN participation, a spreadsheet-based tool and advice for evaluating the business case for provider participation in a CCOP organization. A comparative, case-study approach was used to identify key components of the business case for hospitals attempting to support a CCOP research infrastructure. Semistructured interviews were conducted with providers and administrators. Key themes were identified and used to develop the financial analysis tool. Key components of the business case included CCOP start-up costs, direct revenue from the NCI CCOP grant, direct expenses required to maintain the CCOP research infrastructure, and incidental benefits, most notably downstream revenues from CCOP patients. The authors recognized the value of incidental benefits as an important contributor to the business case for CCOP participation; however, currently, this component is not calculated. The current results indicated that providing a method for documenting the business case for CCOP or other PBRN involvement will contribute to the long-term sustainability and expansion of these programs by improving providers' understanding of the financial implications of participation. Copyright © 2011 American Cancer Society.

  5. Joint Global Change Research Institute (JGCRI)

    Data.gov (United States)

    Federal Laboratory Consortium — The Joint Global Change Research Institute (JGCRI) is dedicated to understanding the problems of global climate change and their potential solutions. The Institute...

  6. Breast Cancer: Surgery at the South Egypt Cancer Institute

    OpenAIRE

    Salem, Ahmed A.S.; Salem, Mohamed Abou Elmagd; Abbass, Hamza

    2010-01-01

    Breast cancer is the most frequent malignant tumor in women worldwide. In Egypt, it is the most common cancer among women, representing 18.9% of total cancer cases (35.1% in women and 2.2% in men) among the Egypt National Cancer Institute?s (NCI) series of 10,556 patients during the year 2001, with an age-adjusted rate of 49.6 per 100,000 people. In this study, the data of all breast cancer patients presented to the surgical department of the South Egypt cancer Institute (SECI) hospital durin...

  7. Institutional Support : Makerere Institute of Social Research (MISR ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Makerere Institute of Social Research (MISR), Uganda, is the former East African Institute of Social and Economic Research (EAISR), which was established in 1948. MISR - an integral part of Makerere University - relies on project or consultancy revenue for its research, capacity building and outreach activities. This grant ...

  8. Institutional Repositories in Indian Universities and Research Institutes: A Study

    Science.gov (United States)

    Krishnamurthy, M.; Kemparaju, T. D.

    2011-01-01

    Purpose: The purpose of this paper is to report on a study of the institutional repositories (IRs) in use in Indian universities and research institutes. Design/methodology/approach: Repositories in various institutions in India were accessed and described in a standardised way. Findings: The 20 repositories studied covered collections of diverse…

  9. Institutional failures and transaction costs of Bulgarian private research institutes

    OpenAIRE

    Nozharov, Shteryo

    2016-01-01

    The paper analyses the reasons for poor performance of private research institutes in Bulgaria. In this regard the Institutional Economics methods are used. A connection between smart growth policy goals and Bulgarian membership in EU is made. The gaps in the institutional environment are identified as well as measures for their elimination are proposed. The main accent of the study is put on the identification of transaction costs, arisen as a result of the failures of the institutional envi...

  10. Research Institute for Medical Biophysics

    International Nuclear Information System (INIS)

    Wynchank, S.

    1989-01-01

    The effects of ionising and non-ionising radiation on rodent tumours and normal tissue were studied in terms of cellular repair and the relevant biochemical and biophysical changes following radiation. Rodent tumours investigated in vivo were the CaNT adenocarcinoma and a chemically induced transplantable rhabdomyosarcoma. Radiations used were 100KVp of X-Rays, neutron beams, various magnetic fields, and microwave radiation of 2450MHz. The biochemical parameters measured were, inter alia, levels of adenosine-5'-triphoshate (ATP) and the specific activity of hexokinase (HK). Metabolic changes in ATP levels and the activity of HK were observed in tumour and normal tissues following ionising and non-ionising radiation in normoxia and hypoxia. The observation that the effect of radiation and chemotherapeutic treatment of some tumours may be size dependent can possibly now be explained by the variation of ATP content with tumour size. The enhanced tumour HK specific activity implies increased metabolism, possibly a consequence of cellular requirements to maintain homeostasis during repair processes. Other research projects of the Research Institute for Medical Biophysics involved, inter alia, gastroesophageal scintigraphies to evaluate the results of new forms of therapy. 1 ill

  11. Institutional Support : Kenya Institute for Public Policy Research and ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    In 2006 the Government of Kenya passed an Act of Parliament making the Kenya Institute for Public Policy Research and Analysis (KIPPRA) the government's lead socioeconomic research institute. The Act exerts enormous demands on KIPPRA at a time when it is trying to recover from the senior staff turnover suffered in ...

  12. Cancer research and radiotherapy

    International Nuclear Information System (INIS)

    Matsuzawa, Taiju

    1978-01-01

    An actual condition of cancer, and the basis and a future view of radiotherapy were described by adding generally established biological and biochemical knowledge to the author's research. It was described that the relapse of cancer after irradiation was induced from outside of cancerous mass, and the nature of relapsed cancerous cells group was also stated. The histological structure of cancer from a view of cell movement and radioresistant cancerous cells group were described. The differentiation of cancerous cells were described, and a study of inhibition of cancer by redifferentiation was considered. It is important to grasp characteristics and a limit of radiotherapy for cancer, to systematize and materialize reasonable therapy which uses drug and immunotherapy together with surgery, and to use radiotherapy reasonably together with redifferentiation therapy of cancerous cells by extracting characteristics and a limit of radiationtherapy from an actual condition of cancer. (Serizawa, K.)

  13. ICPC Pilots International Student Training, Paving a Path for Tomorrow’s Cancer Researchers | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The Office of Cancer Clinical Proteomics Research at the National Cancer Institute, part of the United States National Institutes of Health, is spearheading the preparationand training of the proteogenomic research workforce on an international scale.

  14. Gas Research Institute wetland research program

    International Nuclear Information System (INIS)

    Wilkey, P.L.; Zimmerman, R.E.; Isaacson, H.R.

    1992-01-01

    As part of three ongoing research projects, the Gas Research Institute (GRI) is studying the natural gas industry's impacts on wetlands and how to manage operations so that impacts can be minimized or eliminated. The objective of the first project is to gain a better understanding of the causes and processes of wetland loss in the Louisiana deltaic plain and what role gas pipeline canals play in wetland loss. On the basis of information gathered from the first projects, management and mitigation implications for pipeline construction and maintenance will be evaluated. The objective of the second project is to assess the floral and faunal communities on existing rights-of-way (ROWs) that pass through numerous types of wetlands across the United States. The emphasis of the project is on pipelines that were installed within the past five years. The objective of the third project is to evaluate the administrative, jurisdictional, technical, and economic issues of wetland mitigation banking. This paper discusses these projects, their backgrounds, some of the results to date, and the deliverables

  15. Harish-Chandra Research Institute, Allahabad

    Indian Academy of Sciences (India)

    The Harish-Chandra Research Institute (known as the Mehta Research Institute of Math- ematics and Mathematical Physics until October 2000) came into existence in 1975, with a donation of some land and Rs. 40 lakhs from the B S Mehta Trust in Calcutta. With the aim of converting it into a top-class research Institute in ...

  16. What Works to Prevent Adolescent Smoking? A Systematic Review of the National Cancer Institute's Research-Tested Intervention Programs

    Science.gov (United States)

    Sherman, Elyse J.; Primack, Brian A.

    2009-01-01

    Background: Cigarette use remains the leading preventable cause of death in the United States. Although school is an ideal setting for antismoking interventions, school-based programs have not been successful in the long term. The purpose of this study was to explore characteristics of programs deemed to be successful short-term Research-Tested…

  17. National Institute of Nursing Research

    Science.gov (United States)

    ... Management Resources Precision Medicine at NINR Research Highlights Data Science and Nursing Research Spotlight on End-of-Life ... Management Resources Precision Medicine at NINR Research Highlights Data Science and Nursing Research Spotlight on End-of-Life ...

  18. Research Universities as Knowledge Networks: The Role of Institutional Research

    Science.gov (United States)

    Chirikov, Igor

    2013-01-01

    This article focuses on the elaboration of institutional research practice, which is an important element of any research university. The study addresses three questions. First, how did institutional research arise, and what is its raison d'etre in a research university? Second, how can institutional research contribute to the improvement of the…

  19. New targets for immunotherapy-based treatment of HPV-related cancers | Center for Cancer Research

    Science.gov (United States)

    Scientists at the Center for Cancer Research and three other cancer research institutions show that immunotherapy treatments that resulted in complete regression of metastatic cervical cancer largely targeted two non-viral antigens. Read more…  

  20. Cancer Clinical Trials at the National Institutes of Health Clinical Center

    Science.gov (United States)

    ... Questions to Ask about Your Treatment Research Cancer Clinical Trials at the National Institutes of Health Clinical Center ... they are eligible for a clinical trial . NCI Clinical Trials at the NIH Clinical Center Cancer research at ...

  1. Using institutional theory in enterprise systems research

    DEFF Research Database (Denmark)

    Svejvig, Per

    2013-01-01

    This paper sets out to examine the use of institutional theory as a conceptually rich lens to study social issues of enterprise systems (ES) research. More precisely, the purpose is to categorize current ES research using institutional theory to develop a conceptual model that advances ES research...

  2. Low Vision Research at the Schepens Eye Research Institute

    National Research Council Canada - National Science Library

    D'Amore, Patricia

    2003-01-01

    This research proposal, Low Vision at the Schepens Eye Research Institute, is a collaborative effort on the part of four Investigators at the Institute whose goal is to advance the studies on low vision...

  3. The business case for provider participation in clinical trials research: an application to the National Cancer Institute's community clinical oncology program.

    Science.gov (United States)

    Song, Paula H; Reiter, Kristin L; Weiner, Bryan J; Minasian, Lori; McAlearney, Ann Scheck

    2013-01-01

    Provider-based research networks (PBRNs) make clinical trials available in community-based practice settings, where most people receive their care, but provider participation requires both financial and in-kind contributions. The aim of this study was to explore whether providers believe there is a business case for participating in PBRNs and what factors contribute to the business case. We use a multiple case study methodology approach to examine the National Cancer Institute's community clinical oncology program, a long-standing federally funded PBRN. Interviews with 41 key informants across five sites, selected on the basis of organizational maturity, were conducted using a semistructured interview guide. We analyzed interview transcripts using an iterative, deductive process to identify themes and subthemes in the data. We found that a business case for provider participation in PBRNs may exist if both direct and indirect financial benefits are identified and included in the analysis and if the time horizon is long enough to allow those benefits to be realized. We identified specific direct and indirect financial benefits that were perceived as important contributors to the business case and the perceived length of time required for a positive return to accrue. As the lack of a business case may result in provider reluctance to participate in PBRNs, knowledge of the benefits we identified may be crucial to encouraging and sustaining participation, thereby preserving patient access to innovative community-based treatments. The results are also relevant to federally funded PBRNs outside of oncology or to providers considering participation in any clinical trials research.

  4. 76 FR 9353 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute.... Place: Bethesda North Marriott Hotel & Conference Center, 5701 Marinelli Road, Bethesda, MD 20852... Branch, Division of Extramural Activities, National Cancer Institute, 6116 Executive Blvd., Room 8101...

  5. Comment Topic Evolution on a Cancer Institution's Facebook Page.

    Science.gov (United States)

    Tang, Chunlei; Zhou, Li; Plasek, Joseph; Rozenblum, Ronen; Bates, David

    2017-08-23

    Our goal was to identify and track the evolution of the topics discussed in free-text comments on a cancer institution's social media page. We utilized the Latent Dirichlet Allocation model to extract ten topics from free-text comments on a cancer research institution's Facebook™ page between January 1, 2009, and June 30, 2014. We calculated Pearson correlation coefficients between the comment categories to demonstrate topic intensity evolution. A total of 4,335 comments were included in this study, from which ten topics were identified: greetings (17.3%), comments about the cancer institution (16.7%), blessings (10.9%), time (10.7%), treatment (9.3%), expressions of optimism (7.9%), tumor (7.5%), father figure (6.3%), and other family members & friends (8.2%), leaving 5.1% of comments unclassified. The comment distributions reveal an overall increasing trend during the study period. We discovered a strong positive correlation between greetings and other family members & friends (r=0.88; p<0.001), a positive correlation between blessings and the cancer institution (r=0.65; p<0.05), and a negative correlation between blessings and greetings (r=-0.70; p<0.05). A cancer institution's social media platform can provide emotional support to patients and family members. Topic analysis may help institutions better identify and support the needs (emotional, instrumental, and social) of their community and influence their social media strategy.

  6. National Nuclear Research Institute Annual Report 2013

    International Nuclear Information System (INIS)

    2014-01-01

    The report highlights the activities of the National Nuclear Research Institute (NNRI) of the Ghana Atomic Energy Commission for the year 2013, grouped under the following headings: Centres under the institute namely Nuclear Reactors Research Centre (NRRC); Accelerator Research Centre (ARC); Engineering Services Centre (ESC); National Radioactive Waste Management Centre (NRWMC); Nuclear Chemistry and Environmental Research Centre (NCERC); Nuclear Applications Centre (NAC) and National Data Centre (NDC). (A. B.)

  7. Reporting of serious adverse events during cancer clinical trials to the institutional review board: an evaluation by the research on adverse drug events and reports (RADAR) project.

    Science.gov (United States)

    Belknap, S M; Georgopoulos, C H; Lagman, J; Weitzman, S A; Qualkenbush, L; Yarnold, P R; Edwards, B J; McKoy, J M; Trifilio, S M; West, D P

    2013-12-01

    Global introspection is considered an unreliable method for attribution of causality of serious adverse events (SAEs), yet remains widely used for cancer drug clinical trials. Here, we compare structured case abstraction (SCA) to the routine method for detecting, evaluating, and reporting ADEs during cancer drug clinical trials to an Institutional Review Board (IRB). We obtained all SAE reports (2001-2008) received by one IRB for six clinical trials involving bevacizumab or oxaliplatin for treatment of gastrointestinal cancers. We compared the routine IRB SAE method to SCA for adverse event detection and causality attribution. Of 205 adverse events, 182 events (75%) were not reported; of these, 6 (20%) of 30 SAEs requiring an IRB report were unreported. For the 10 item Naranjo score, the amount of information useful for causality attribution was higher with SCA than the routine method (6.0 vs. 2.4 items, P < .0001). One-fifth of SAEs requiring an IRB report were unreported to the IRB via the routine method. SCA provided more useful information as to whether an SAE was caused by a cancer drug exposure. Our results suggest that SCA may improve SAE detection and the accuracy of attribution of causality during cancer drug clinical trials. © 2013, The American College of Clinical Pharmacology.

  8. Nanotechnology in Cancer Research

    Science.gov (United States)

    The NCI Office of Cancer Nanotechnology Research has had a major impact on bringing novel nano-enabled solutions through the pre-clinical space. The strategic framework of this effort is presented here.

  9. Institutional Support : Institute for Research on Political Economy in ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Institut de recherche empirique en économie politique (IREEP) is an independent nonprofit organization established in 2004 with a view to contributing to the education of the next generation of teachers and researchers in political economy in Bénin and West Africa. IREEP has successfully integrated academic training ...

  10. Institutional research and development, FY 1987

    International Nuclear Information System (INIS)

    Struble, G.L.; Lawler, G.M.; Crawford, R.B.; Kirvel, R.D.; Peck, T.M.; Prono, J.K.; Strack, B.S.

    1987-01-01

    The Institutional Research and Development program at Lawrence Livermore National Laboratory fosters exploratory work to advance science and technology, disciplinary research to develop innovative solutions to problems in various scientific fields, and long-term interdisciplinary research in support of defense and energy missions. This annual report describes research funded under this program for FY87

  11. Institutional research and development, FY 1987

    Energy Technology Data Exchange (ETDEWEB)

    Struble, G.L.; Lawler, G.M.; Crawford, R.B.; Kirvel, R.D.; Peck, T.M.; Prono, J.K.; Strack, B.S. (eds.)

    1987-01-01

    The Institutional Research and Development program at Lawrence Livermore National Laboratory fosters exploratory work to advance science and technology, disciplinary research to develop innovative solutions to problems in various scientific fields, and long-term interdisciplinary research in support of defense and energy missions. This annual report describes research funded under this program for FY87. (DWL)

  12. Central Institute for Nuclear Research (1956 - 1979)

    International Nuclear Information System (INIS)

    Flach, G.; Bonitz, M.

    1979-12-01

    The Central Institute for Nuclear Research (ZfK) of the Academy of Sciences of the GDR is presented. This first overall survey covers the development of the ZfK since 1956, the main research activities and results, a description of the departments responsible for the complex implementation of nuclear research, the social services for staff and the activities of different organizations in the largest central institute of the Academy of Sciences of the GDR. (author)

  13. 78 FR 44577 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2013-07-24

    ... and AIDS Malignancy priorities. Place: National Cancer Institute, NIH, Building 10, Room 10S255, 10... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute.... App.), notice is hereby given of a meeting of the National Cancer Institute Board of Scientific...

  14. 78 FR 46357 - National Cancer Institute; Amended Notice of Meeting

    Science.gov (United States)

    2013-07-31

    ... Cancer Institute Board of Scientific Advisors ad hoc Subcommittee on HIV/AIDS Malignancy, August 08, 2013, 10:30 a.m. to 12:00 p.m., National Cancer Institute, NIH, Building 10, Room 10S255, 10 Center Drive... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute...

  15. 75 FR 7489 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-02-19

    ... Institute Special Emphasis Panel; NCI Cancer Nanotechnology Training (R25) and Career Development Award (K99... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel; The Early Detection...

  16. 78 FR 16272 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-03-14

    ...: National Cancer Institute Special Emphasis Panel, Nanotechnology RNA Therapeutics. Date: April 18-19, 2013... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel, NCI Provocative Questions. Date: March 28, 2013. Time: 7:30 a.m...

  17. 75 FR 26968 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-13

    ...: National Cancer Institute Special Emphasis Panel; Nanotechnology Imaging and Sensing Platforms. Date: June... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel; Adult Brain Tumor Consortium. Date: May 20, 2010. Time: 1 p.m...

  18. Research in Institutional Economics in Management Science

    DEFF Research Database (Denmark)

    Foss, Kirsten; Foss, Nicolai Juul

    This report maps research in institutional economics in management science in the European Union for the 1995 to 2002 period. The reports applies Internet search based on a university listing, search on journal databases, key informants and an internet-based survey. 195 researchers are identified...... is partly explainable by the highly pragmatic way in which research in management science is typically conducted (so that institutional economics approaches are likely to be merely one type of input among many). Keywords Institutional economics, management science, European union....

  19. Brazil opens its first private research institute

    Science.gov (United States)

    Ivanissevich, Alicia

    2017-05-01

    The Brazilian filmmaker João Moreira Salles - whose family owns one of the largest banks in Brazil - has established a new institute in Rio de Janeiro that will support basic research across all sciences.

  20. Teacher Research and University Institutional Review Boards

    Science.gov (United States)

    Brown, Pamela U.

    2010-01-01

    The author combines a literature review with a theoretical analysis of the interface between teacher researchers and Institutional Review Boards in higher education. Maintaining that teacher researchers are "creators of knowledge" (Castle, 2006, p. 2), the article explores the lack of fit between insider research with an emic design and the…

  1. Institutional Support : Economic Policy Research Centre (EPRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Economic Policy Research Centre (EPRC) was established in 1993 as an autonomous not-for-profit policy research institute with support from the Government of Uganda, donor agencies and ... Addressing Africa's unmet need for family planning by intensifying sexual and reproductive and adolescent health research.

  2. Administrative Assistant | Center for Cancer Research

    Science.gov (United States)

    An administrative assistant position is available immediately in the Laboratory of Genome Integrity (LGI) within the Center for Cancer Research (CCR) in the National Cancer Institute (NCI). The LGI is actively looking for someone with administrative skills who will facilitate personnel, travel and related demands that support the laboratory chief, all principal investigators and postdoctoral fellows and laboratory support staff. 

  3. Pregnancy associated breast cancer: an institutional experience.

    Science.gov (United States)

    Gogia, A; Deo, S V S; Shukla, N K; Mohanti, B K; Raina, V

    2014-01-01

    Pregnancy-associated breast cancer (PABC) has been defined as breast cancer diagnosed during pregnancy or within 1 year of delivery. There is a paucity of data on PABC from India. The aim of our study was to assess the clinical-pathological parameters and outcome of PABC at Institute Rotary Cancer Hospital, All India Institute of Medical Sciences. We screened approximately 3,750 cases registered from January 2001 to December 2012 and found 26 cases of PABC. Patients' records were obtained from the computer database using International Classification of Diseases code (C-50). The median age was 26 years (range 20-35). The median duration of symptoms was 11.5 months. The American Joint Committee on Cancer stage distribution was Stage I - 1, Stage II - 3, Stage III - 14 and in Stage IV - 8 patients. Median clinical tumor size is 5.5 cm. Four patients were presented with the inflammatory breast cancer. Positive family history was elicited in three patients. Twenty-one patients were diagnosed after delivery, two patients in the first trimester, two patients in the second trimester and three patients in the third trimester. Estrogen receptor (ER), progesterone receptor (PR) negativity and human epidermal growth factor receptor 2 (HER2/neu) positivity was 56% and 38%, respectively. Nearly, 40% of patients had a high-grade tumor and 70% had pathological node positivity. With a median follow-up of 33 months, 3 years relapse free survival and overall survival was 40% and 50% respectively. Bone was the most common site for systemic relapse. PABC constituted 0.7% of all breast cancer patients. It is associated with advanced stage at presentation. Half of them were ER/PR negative and one-third was HER2/neu positive.

  4. Final Report: Performance Engineering Research Institute

    Energy Technology Data Exchange (ETDEWEB)

    Mellor-Crummey, John [Rice Univ., Houston, TX (United States)

    2014-10-27

    This document is a final report about the work performed for cooperative agreement DE-FC02-06ER25764, the Rice University effort of Performance Engineering Research Institute (PERI). PERI was an Enabling Technologies Institute of the Scientific Discovery through Advanced Computing (SciDAC-2) program supported by the Department of Energy's Office of Science Advanced Scientific Computing Research (ASCR) program. The PERI effort at Rice University focused on (1) research and development of tools for measurement and analysis of application program performance, and (2) engagement with SciDAC-2 application teams.

  5. Retooling institutional support infrastructure for clinical research.

    Science.gov (United States)

    Snyder, Denise C; Brouwer, Rebecca N; Ennis, Cory L; Spangler, Lindsey L; Ainsworth, Terry L; Budinger, Susan; Mullen, Catherine; Hawley, Jeffrey; Uhlenbrauck, Gina; Stacy, Mark

    2016-05-01

    Clinical research activities at academic medical centers are challenging to oversee. Without effective research administration, a continually evolving set of regulatory and institutional requirements can divert investigator and study team attention away from a focus on scientific gain, study conduct, and patient safety. However, even when the need for research administration is recognized, there can be struggles over what form it should take. Central research administration may be viewed negatively, with individual groups preferring to maintain autonomy over processes. Conversely, a proliferation of individualized approaches across an institution can create inefficiencies or invite risk. This article describes experiences establishing a unified research support office at the Duke University School of Medicine based on a framework of customer support. The Duke Office of Clinical Research was formed in 2012 with a vision that research administration at academic medical centers should help clinical investigators navigate the complex research environment and operationalize research ideas. The office provides an array of services that have received high satisfaction ratings. The authors describe the ongoing culture change necessary for success of the unified research support office. Lessons learned from implementation of the Duke Office of Clinical Research may serve as a model for other institutions undergoing a similar transition. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  6. 75 FR 44274 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-07-28

    ... Cancer Institute Special Emphasis Panel, Nanotechnology Imaging and Sensing Platforms for Improved Diagnosis of Cancer. Date: August 31, 2010. Time: 12 p.m. to 1:30 p.m. Agenda: To review and evaluate... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute...

  7. 76 FR 69744 - National Cancer Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-11-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel, Cancer Diagnostic and Therapeutic Agents Enabled by Nanotechnology. Date: November 29, 2011. Time: 8 a.m. to 7 p.m...

  8. 75 FR 42449 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2010-07-21

    ... Research Programs and Updates of the Implementation of the Clinical Trials and Translational Research....395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers Support; 93...

  9. Cancer Research UK | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cancer Research UK. Cancer Research UK. https://www.cancerresearchuk.org/. The Economics of Tobacco Control Research Initiative. The Economics of Tobacco Control Research Initiative funds innovative fiscal policy research supporting tobacco control in low and middle-income countries. View more. The Economics ...

  10. Research in Institutional Economics in Management Science

    DEFF Research Database (Denmark)

    Foss, Kirsten; Foss, Nicolai Juul

    This report maps research in institutional economics in management science in the European Union for the 1995 to 2002 period. The reports applies Internet search based on a university listing, search on journal databases, key informants and an internet-based survey. 195 researchers are identified....... In (sub-)disciplinary terms, organization, strategy, corporate governance, and international business are the major areas of application of institutional economics ideas. In terms of countries, the EU strongholds are Holland, Denmark, UK, and Germany. There is apparently no or very little relevant...... research in Ireland, Portugal, Luxembourg and Greece. Based on the findings of the report, it seems warranted to characterize the EU research effort in the field as being rather dispersed and uncoordinated. Thus, there are no specialized journals, associations or PhD courses. This state of affairs...

  11. Adapting Institutional Research to Changing Student Populations.

    Science.gov (United States)

    Cohen, Arthur M.

    Institutional research (IR) in community/junior colleges in past years has been limited to gathering data for external agencies, concentrating on raw demographic data and student flow studies. IR should be directed toward providing data for administrative decisions and for successful maintenance of college operations. In spite of the heavy demands…

  12. The John Milner Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

    Science.gov (United States)

    The Nutritional Science Research Group in the Division of Cancer Prevention at the National Cancer Institute, National Institutes of Health and the Department of Nutrition at the Clinical Center, National Institutes of Health, and the U.S. Department of Agriculture’s Beltsville Human Nutrition Research Center are offering a one-week educational opportunity in Nutrition and Cancer Prevention Research for individuals with a sustained commitment to nutrition and health promotion. |

  13. Northeast Regional Cancer Institute's Cancer Surveillance and Risk Factor Program

    Energy Technology Data Exchange (ETDEWEB)

    Lesko, Samuel M.

    2007-07-31

    OBJECTIVES The Northeast Regional Cancer Institute is conducting a program of ongoing epidemiologic research to address cancer disparities in northeast Pennsylvania. Of particular concern are disparities in the incidence of, stage at diagnosis, and mortality from colorectal cancer. In northeast Pennsylvania, age-adjusted incidence and mortality rates for colorectal cancer are higher, and a significantly smaller proportion of new colorectal cancer cases are diagnosed with local stage disease than is observed in comparable national data. Further, estimates of the prevalence of colorectal cancer screening in northeast Pennsylvania are lower than the US average. The Northeast Regional Cancer Institute’s research program supports surveillance of common cancers, investigations of cancer risk factors and screening behaviors, and the development of resources to further cancer research in this community. This project has the following specific objectives: I. To conduct cancer surveillance in northeast Pennsylvania. a. To monitor incidence and mortality for all common cancers, and colorectal cancer, in particular, and b. To document changes in the stage at diagnosis of colorectal cancer in this high-risk, underserved community. II. To conduct a population-based study of cancer risk factors and screening behavior in a six county region of northeast Pennsylvania. a. To monitor and document changes in colorectal cancer screening rates, and b. To document the prevalence of cancer risk factors (especially factors that increase the risk of colorectal cancer) and to identify those risk factors that are unusually common in this community. APPROACH Cancer surveillance was conducted using data from the Northeast Regional Cancer Institute’s population-based Regional Cancer Registry, the Pennsylvania Cancer Registry, and NCI’s SEER program. For common cancers, incidence and mortality were examined by county within the region and compared to data for similar populations in the US

  14. Institute for Safety Research. Annual report 1992

    International Nuclear Information System (INIS)

    Weiss, F.P.; Boehmert, J.

    1993-11-01

    The Institute is concerned with evaluating the design based safety and increasing the operational safety of technical systems which include serious sources of danger. It is further occupied with methods of mitigating the effects of incidents and accidents. For all these goals the institute does research work in the following fields: modelling and simulation of thermofluid dynamics and neutron kinetics in cases of accidents; two-phase measuring techniques; safety-related analyses and characterizing of mechanical behaviours of material; measurements and calculations of radiation fields; process and plant diagnostics; development and application of methods of decision analysis. This annual report gives a survey of projects and scientific contributions (e.g. Single rod burst tests with ZrNb1 cladding), lists publications, institute seminars and workshops, names the personal staff and describes the organizational structure. (orig./HP)

  15. Integrated Cancer Repository for Cancer Research

    Science.gov (United States)

    2017-05-05

    Pancreatic Cancer; Thyroid Cancer; Lung Cancer; Esophageal Cancer; Thymus Cancer; Colon Cancer; Rectal Cancer; GIST; Anal Cancer; Bile Duct Cancer; Duodenal Cancer; Gallbladder Cancer; Gastric Cancer; Liver Cancer; Small Intestine Cancer; Peritoneal Surface Malignancies; Familial Adenomatous Polyposis; Lynch Syndrome; Bladder Cancer; Kidney Cancer; Penile Cancer; Prostate Cancer; Testicular Cancer; Ureter Cancer; Urethral Cancer; Hypopharyngeal Cancer; Laryngeal Cancer; Lip Cancer; Oral Cavity Cancer; Nasopharyngeal Cancer; Oropharyngeal Cancer; Paranasal Sinus Cancer; Nasal Cavity Cancer; Salivary Gland Cancer; Skin Cancer; CNS Tumor; CNS Cancer; Mesothelioma; Breastcancer; Leukemia; Melanoma; Sarcoma; Unknown Primary Tumor; Multiple Myeloma; Ovarian Cancer; Endometrial Cancer; Vaginal Cancer

  16. Prognostic significance of NPM1 mutations in the absence of FLT3-internal tandem duplication in older patients with acute myeloid leukemia: a SWOG and UK National Cancer Research Institute/Medical Research Council report.

    Science.gov (United States)

    Ostronoff, Fabiana; Othus, Megan; Lazenby, Michelle; Estey, Elihu; Appelbaum, Frederick R; Evans, Anna; Godwin, John; Gilkes, Amanda; Kopecky, Kenneth J; Burnett, Alan; List, Alan F; Fang, Min; Oehler, Vivian G; Petersdorf, Stephen H; Pogosova-Agadjanyan, Era L; Radich, Jerald P; Willman, Cheryl L; Meshinchi, Soheil; Stirewalt, Derek L

    2015-04-01

    Younger patients with acute myeloid leukemia (AML) harboring NPM1 mutations without FLT3-internal tandem duplications (ITDs; NPM1-positive/FLT3-ITD-negative genotype) are classified as better risk; however, it remains uncertain whether this favorable classification can be applied to older patients with AML with this genotype. Therefore, we examined the impact of age on the prognostic significance of NPM1-positive/FLT3-ITD-negative status in older patients with AML. Patients with AML age ≥ 55 years treated with intensive chemotherapy as part of Southwest Oncology Group (SWOG) and UK National Cancer Research Institute/Medical Research Council (NCRI/MRC) trials were evaluated. A comprehensive analysis first examined 156 patients treated in SWOG trials. Validation analyses then examined 1,258 patients treated in MRC/NCRI trials. Univariable and multivariable analyses were used to determine the impact of age on the prognostic significance of NPM1 mutations, FLT3-ITDs, and the NPM1-positive/FLT3-ITD-negative genotype. Patients with AML age 55 to 65 years with NPM1-positive/FLT3-ITD-negative genotype treated in SWOG trials had a significantly improved 2-year overall survival (OS) as compared with those without this genotype (70% v 32%; P 65 years with this genotype (70% v 27%; P 65 years was marginal (27% v 16%; P = .33). In multivariable analysis, NPM1-positive/FLT3-ITD-negative genotype remained independently associated with an improved OS in patients age 55 to 65 years (P = .002) but not in those age > 65 years (P = .82). These results were confirmed in validation analyses examining the NCRI/MRC patients. NPM1-positive/FLT3-ITD-negative genotype remains a relatively favorable prognostic factor for patients with AML age 55 to 65 years but not in those age > 65 years. © 2015 by American Society of Clinical Oncology.

  17. Prognostic Significance of NPM1 Mutations in the Absence of FLT3–Internal Tandem Duplication in Older Patients With Acute Myeloid Leukemia: A SWOG and UK National Cancer Research Institute/Medical Research Council Report

    Science.gov (United States)

    Ostronoff, Fabiana; Othus, Megan; Lazenby, Michelle; Estey, Elihu; Appelbaum, Frederick R.; Evans, Anna; Godwin, John; Gilkes, Amanda; Kopecky, Kenneth J.; Burnett, Alan; List, Alan F.; Fang, Min; Oehler, Vivian G.; Petersdorf, Stephen H.; Pogosova-Agadjanyan, Era L.; Radich, Jerald P.; Willman, Cheryl L.; Meshinchi, Soheil; Stirewalt, Derek L.

    2015-01-01

    Purpose Younger patients with acute myeloid leukemia (AML) harboring NPM1 mutations without FLT3–internal tandem duplications (ITDs; NPM1-positive/FLT3-ITD–negative genotype) are classified as better risk; however, it remains uncertain whether this favorable classification can be applied to older patients with AML with this genotype. Therefore, we examined the impact of age on the prognostic significance of NPM1-positive/FLT3-ITD–negative status in older patients with AML. Patients and Methods Patients with AML age ≥ 55 years treated with intensive chemotherapy as part of Southwest Oncology Gorup (SWOG) and UK National Cancer Research Institute/Medical Research Council (NCRI/MRC) trials were evaluated. A comprehensive analysis first examined 156 patients treated in SWOG trials. Validation analyses then examined 1,258 patients treated in MRC/NCRI trials. Univariable and multivariable analyses were used to determine the impact of age on the prognostic significance of NPM1 mutations, FLT3-ITDs, and the NPM1-positive/FLT3-ITD–negative genotype. Results Patients with AML age 55 to 65 years with NPM1-positive/FLT3-ITD–negative genotype treated in SWOG trials had a significantly improved 2-year overall survival (OS) as compared with those without this genotype (70% v 32%; P 65 years with this genotype (70% v 27%; P 65 years was marginal (27% v 16%; P = .33). In multivariable analysis, NPM1-positive/FLT3-ITD–negative genotype remained independently associated with an improved OS in patients age 55 to 65 years (P = .002) but not in those age > 65 years (P = .82). These results were confirmed in validation analyses examining the NCRI/MRC patients. Conclusion NPM1-positive/FLT3-ITD–negative genotype remains a relatively favorable prognostic factor for patients with AML age 55 to 65 years but not in those age > 65 years. PMID:25713434

  18. Cancer Prevention Research in China.

    Science.gov (United States)

    Yu, Siwang; Yang, Chung S; Li, Junyao; You, Weicheng; Chen, Jianguo; Cao, Ya; Dong, Zigang; Qiao, Youlin

    2015-08-01

    Although cancer incidence and mortality rates in the United States and some European countries have started to decrease, those in developing countries are increasing. China, the most populous developing country, is facing a serious challenge from cancer. Cancer incidence has been increasing for decades, and cancer is the leading cause of death in China. In 2012, the cancer incidence was 174.0 per 100,000, and the cancer mortality was 122.2 per 100,000 in China. In addition to the still-prevalent traditional Chinese cancers of the stomach, liver, esophagus, cervix, and nasopharynx, the incidence of "Western" cancers such those of the lung, breast, and colorectum has increased alarmingly in recent years. These increases are likely due to the lifestyle and environmental changes associated with rapid economic development and population aging. More importantly, a large portion of these cancers are preventable. Researchers in China have made important contributions to cancer prevention research, especially in the traditional Chinese cancers. More cancer prevention research and measures, especially on the major emerging cancers, are urgently needed. This review article highlights some of the past achievements and present needs in cancer prevention research in China and suggests important areas for future studies. ©2015 American Association for Cancer Research.

  19. Research Ethics: Institutional Review Board Oversight of Art Therapy Research

    Science.gov (United States)

    Deaver, Sarah P.

    2011-01-01

    By having their research proposals reviewed and approved by Institutional Review Boards (IRBs), art therapists meet important ethical principles regarding responsibility to research participants. This article provides an overview of the history of human subjects protections in the United States; underlying ethical principles and their application…

  20. Alligator Rivers Regions Research Institute research report 1983-84

    International Nuclear Information System (INIS)

    1984-01-01

    The Institute undertakes and coordinates research required to ensure the protection of the environment in the Alligator Rivers Region from any consequences resulting from the mining and processing of uranium ore. Research projects outlined are in aquatic biology, terrestrial ecology, analytical chemistry, environmental radioactivity and geomorphology

  1. Plasma Physics Research at an Undergraduate Institution

    Science.gov (United States)

    Padalino, Stephen

    2007-11-01

    Undergraduate research experiences have motivated many physics majors to continue their studies at the graduate level. The Department of Physics and Astronomy at SUNY Geneseo, a primarily undergraduate institution, recognizes this simple reality and is committed to ensuring research opportunities are available to interested majors beginning as early as their freshman year. Every year for more than a decade, as many as two dozen students and 8 faculty members have worked on projects related to high energy density physics and inertial confinement fusion during the summer months and the academic year. By working with their research sponsors, it has been possible to identify an impressive number of projects suitable for an institution such as Geneseo. These projects tend to be hands-on and require teamwork and innovation to be successful. They also take advantage of in-house capabilities such as the 2 MV tandem pelletron accelerator, a scanning electron microscope, a duoplasmatron ion deposition system and a 64 processor computing cluster. The end products of their efforts are utilized at the sponsoring facilities in support of nationally recognized programs. In this talk, I will discuss a number of these projects and point out what made them attractive and appropriate for an institution like Geneseo, the direct and indirect benefits of the research opportunities for the students and faculty, and how the national programs benefited from the cost-effective use of undergraduate research. In addition, I will discuss the importance of exposure for both students and faculty mentors to the larger scientific community through posters presentations at annual meetings such as the DPP and DNP. Finally, I will address the need for even greater research opportunities for undergraduate students in the future and the importance of establishing longer ``educational pipelines'' to satisfy the ever growing need for top-tier scientists and engineers in industry, academia and the

  2. 78 FR 44136 - Submission for OMB review; 30-day Comment Request: National Cancer Institute (NCI) Cancer...

    Science.gov (United States)

    2013-07-23

    ... Act of 1995, the National Institutes of Health (NIH), has submitted to the Office of Management and... associated response time, should be directed to the: Office of Management and Budget, Office of Regulatory...: Dorothy Farrell, Center for Strategic Scientific Initiatives, Office of Cancer Nanotechnology Research...

  3. The Swiss Institute for Nuclear Research SIN

    CERN Document Server

    Pritzker, Andreas

    2014-01-01

    This book tells the story of the Swiss Institute for Nuclear Research (SIN). The institute was founded in 1968 and became part of the Paul Scherrer Institute (PSI) in 1988. Its founding occurred at a time when physics was generally considered the key discipline for technological and social development. This step was unusual for a small country like Switzerland and showed courage and foresight. Equally unusual were the accomplishments of SIN, compared with similar institutes in the rest of the world, as well as its influence on Swiss, and partially also on international politics of science. That this story is now available in a widely understandable form is due to the efforts of some physicists, who took the initiative as long as contemporary witnesses could still be questioned. As is usually the case, official documents always show just an excerpt of what really happened. An intimate portrayal of people who contributed to success requires personal memories. This text relies on both sources. In addition, the e...

  4. Institutional Fact Book: Catalyst for an Integrated Institutional Research Program.

    Science.gov (United States)

    Smith, Glynton

    1983-01-01

    Broad understanding of an institution is fundamental to strategic planning, and information and communication are integral parts of this understanding. An institutional fact book used at Georgia State University is discussed both as a basic information system and as a practical communication vehicle. (MLW)

  5. 78 FR 4422 - National Cancer Institute; Notice of Closed Meeting

    Science.gov (United States)

    2013-01-22

    ... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel; The Role of..., Ph.D., Scientific Review Administrator, Special Review and Logistics Branch, Division of Extramural...

  6. Institutional research and development, FY 1988

    International Nuclear Information System (INIS)

    1988-01-01

    The Laboratory's Institutional Research and Development (IR and D) Program was established in 1984 to foster exploratory work to advance science and technology, disciplinary research to develop innovative solutions to support our national defense and energy missions. In FY 1988, the IR and D Program was funded by a 2% assessment on the Laboratory's operating budget. Our policy is to use these funds for researching innovative ideas in LLNL's areas of expertise and for developing new areas of expertise that we perceive to be in the national interest. The technical and scientific accomplishments of each project and of each institute funded this year are presented in this report. The projects were selected because they are expected to advance research in important areas that are too basic or too time consuming to be funded by the developmental programs or because they are somewhat risky projects that have the promise of high payoff. We are continually reappraising the IR and D Program. In particular, we seek new candidates for the Director's Initiatives, and we constantly reassess the work in progress. Each year, we make adjustments to further the Laboratory's policy of using the IR and D Program to fund innovative ideas with high potential for enhancing programmatic activities of national importance

  7. Institutional research and development, FY 1988

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    The Laboratory's Institutional Research and Development (IR and D) Program was established in 1984 to foster exploratory work to advance science and technology, disciplinary research to develop innovative solutions to support our national defense and energy missions. In FY 1988, the IR and D Program was funded by a 2% assessment on the Laboratory's operating budget. Our policy is to use these funds for researching innovative ideas in LLNL's areas of expertise and for developing new areas of expertise that we perceive to be in the national interest. The technical and scientific accomplishments of each project and of each institute funded this year are presented in this report. The projects were selected because they are expected to advance research in important areas that are too basic or too time consuming to be funded by the developmental programs or because they are somewhat risky projects that have the promise of high payoff. We are continually reappraising the IR and D Program. In particular, we seek new candidates for the Director's Initiatives, and we constantly reassess the work in progress. Each year, we make adjustments to further the Laboratory's policy of using the IR and D Program to fund innovative ideas with high potential for enhancing programmatic activities of national importance.

  8. Cancer Research in the Media

    Science.gov (United States)

    Cancer Research in the Media (CRiM) is a two-day seminar designed for international journalists to increase their understanding of complex scientific findings, improving their ability to communicate accurate cancer-related information to the public.

  9. Why I Do Cancer Research

    Science.gov (United States)

    World Cancer Research Day is recognized on September 24, 2017. This day presents an opportunity for all of us to remind the world of the critically important roles research and cancer researchers play in reducing the global burden of cancer. Together with ten other global partners, NCI participated in the planning and launch of this initiative, highlighting the amplified impact of international cooperation in the clinical research arena.

  10. Annual report 1988-89: Tata Institute of Fundamental Research

    International Nuclear Information System (INIS)

    Isloor, J.D.

    1989-01-01

    The annual report surveys the work of the Tata Institute of Fundamental Research (TIFR), Bombay, during the fiscal year 1988-89. Most of the research activities are organised and carried out in two schools of the Institute, namely, the School of Mathematics and the School of Physics. In the School of Mathematics, active research is carried out in almost every branch of pure mathematics. The School of Physics is engaged in research activities of both theoretical and experimental nature in high energy physics, astrophysics, cosmic rays, space physics, astronomy, nuclear and atomic physics, condensed matter physics, molecular biology, computer science and communication and microwave engineering. TIFR has a Basic Dental Research Unit which carries out intervention studies on oral cancer and precancerous lesions. Its Homi Bhabha Centre for Science Education (HBCSE) carries out programmes for improvement of science education at all levels in the country. TIFR outstation units are: (1) TIFR Centre at Bangalore which in collaboration with the Indian Institute of Science, Bangalore has a programme in Applications of Mathematics (2) Radio Astronomy Centre, Ooty, (3) Baloon Facility, Hyderabad and (4) National Image Processing Facility, Ooty. The academic and research activities of the schools, new technique and instruments and experimental facilities developed and fabricated by various units of TIFR are briefly described. Faculty and section wise list of staff members is given. Lists of publications by the members and other activities such as colloquia, seminars, conferences etc. are also given. (M.G.B.)

  11. Research Institute for Advanced Computer Science

    Science.gov (United States)

    Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

    2000-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administration's missions. RIACS is located at the NASA Ames Research Center. It currently operates under a multiple year grant/cooperative agreement that began on October 1, 1997 and is up for renewal in the year 2002. Ames has been designated NASA's Center of Excellence in Information Technology. In this capacity, Ames is charged with the responsibility to build an Information Technology Research Program that is preeminent within NASA. RIACS serves as a bridge between NASA Ames and the academic community, and RIACS scientists and visitors work in close collaboration with NASA scientists. RIACS has the additional goal of broadening the base of researchers in these areas of importance to the nation's space and aeronautics enterprises. RIACS research focuses on the three cornerstones of information technology research necessary to meet the future challenges of NASA missions: (1) Automated Reasoning for Autonomous Systems. Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth; (2) Human-Centered Computing. Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities; (3) High Performance Computing and Networking. Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to data analysis of large datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply information technology research to a

  12. Perspectives from the Aldo Leopold Wilderness Research Institute: The Wildland Research institute

    Science.gov (United States)

    J. M. Bowker; H. Ken Cordell; Neelam C. Poudyal

    2014-01-01

    The Wildland Research Institute (WRi) at the University of Leeds (UK) came into being in October 2009. Its origins go back to a United Kingdom research councilfunded seminar series called Wilderness Britain? which ran between 1998 and 2000 and was coordinated from the University of Leeds. This opened up the wider debate on wilderness and rewilding in the UK and later...

  13. International Interdisciplinary Research Institute Project in Senegal

    Science.gov (United States)

    Gueye, Paul

    2010-02-01

    The project of an interdisciplinary research institute in Senegal was initiated in 1993 in Senegal (West Africa) and became a template for a similar project in the US in 1999. Since then, numerous meetings and presentations have been held at various national and international institutions, workshops and conferences. The current development of this partnership includes drafts for a full design of all systems at each facility, as well as the physics, applied health and educational programs to be implemented. The Senegal facility was conceived for scientific capacity building and equally to act as a focal point aimed at using the local scientific expertise. An anticipated outcome would be a contribution to the reduction of an ever-growing brain drain process suffered by the country, and the African continent in general. The development of the project led also to a strong African orientation of the facility: built for international collaboration, it is to be a pan-African endeavor and to serve primarily African countries. The facility received a presidential approval in a 2003 meeting and will develop an interdisciplinary program centered on a strong materials science research which will also allow for the establishment of an advanced analytical (physical chemistry) laboratory. A central part of the facility will be linked to state-of-the art accelerator mass spectrometry, cyclotron and low energy electromagnetic accelerator systems. )

  14. Inhalation Toxicology Research Institute annual report 1987-1988

    International Nuclear Information System (INIS)

    Mauderly, J.L.; Mewhinney, J.A.; Bechtold, W.E.; Sun, J.D.; Coons, T.A.

    1988-12-01

    section, Deposition and Fate of Inhaled Toxicants, describes factors influencing the uptake of inhaled materials and their initial interactions in the body. The third and fourth sections, Health Effects of Inhaled Radionuclides and Health Effects of Inhaled Chemical Toxicants, describe recent progress in the fields of radiation and chemical toxicology, respectively. The fifth section, Mechanisms of Carcinogenesis, reflects progress in the understanding of the mechanisms by which radiation and chemicals induce cancer. Similarly, the sixth section, Mechanisms of Non-Carcinogenic Responses to Inhaled Toxicants describes research on the development of diseases other than cancer. The seventh section, The Application of Mathematical Modeling to Health Issues, describes efforts to predict health risks by using computer-based models and limited experimental or epidemiological data. The final section, Studies at the University of Utah, describes progress in studies conducted by University of Utah scientists funded by subcontract through this Institute

  15. Rectal Cancer: Treatment, Research and Quality of Life, Facebook Live Event

    Science.gov (United States)

    The National Cancer Institute hosted a Facebook Live to discuss rectal cancer treatment, research, and quality of life. The event featured subject matter experts Carmen Allegra, MD, of the National Cancer Institute and University of Florida Health, Deborah Schrag, MD, MPH, of Dana-Farber Cancer Institute and moderator

  16. Overview of Gas Research Institute environmental research programs

    International Nuclear Information System (INIS)

    Evans, J.M.

    1991-01-01

    The Gas Research Institute (GRI) is a private not-for-profit membership organization of natural gas pipelines, distribution companies and natural gas producers. GRI's purpose is to plan, to manage and to develop financing for a gas-related research and development (R and D) program on behalf of its members and their customers. GRI does not do any research itself. GRI's R and D program is designed to provide advanced technologies for natural gas supply, transport, storage, distribution and end-use applications in all markets. In addition, basic research is conducted for GRI in these areas to build a foundation for future technology breakthroughs. Work in the Environment and Safety Research Department includes sections interested in: supply related research, air quality research, end use equipment safety research, gas operations safety research, and gas operations environmental research. The Natural Gas Supply Program has research ongoing in such areas as: restoration of pipeline right-of-ways; cleaning up town gas manufacturing sites; the development of methanogenic bacteria for soil and groundwater cleanup; development of biological fluidized carbon units for rapid destruction of carbonaceous compounds; research on liquid redox sulfur recovery for sulfur removal from natural gas; research on produced water and production wastes generated by the natural gas industry; environmental effects of coalbed methane production; and subsurface effects of natural gas operations. The western coalbed methane and ground water programs are described

  17. National Space Biomedical Research Institute Annual Report

    Science.gov (United States)

    2000-01-01

    This report summarizes the activities of the National Space Biomedical Research Institute (NSBRI) during FY 2000. The NSBRI is responsible for the development of countermeasures against the deleterious effects of long-duration space flight and performs fundamental and applied space biomedical research directed towards this specific goal. Its mission is to lead a world-class, national effort in integrated, critical path space biomedical research that supports NASA's Human Exploration and Development of Space (HEDS) Strategic Plan by focusing on the enabling of long-term human presence in, development of, and exploration of space. This is accomplished by: designing, testing and validating effective countermeasures to address the biological and environmental impediments to long-term human space flight; defining the molecular, cellular, organ-level, integrated responses and mechanistic relationships that ultimately determine these impediments, where such activity fosters the development of novel countermeasures; establishing biomedical support technologies to maximize human performance in space, reduce biomedical hazards to an acceptable level, and deliver quality medical care; transferring and disseminating the biomedical advances in knowledge and technology acquired through living and working in space to the general benefit of mankind, including the treatment of patients suffering from gravity- and radiation-related conditions on Earth; and ensuring open involvement of the scientific community, industry and the public at large in the Institute's activities and fostering a robust collaboration with NASA, particularly through NASA's Lyndon B. Johnson Space Center. Attachment:Appendices (A,B,C,D,E,F,G,H,I,J,K,L,M,N,O, and P.).

  18. Research Associate | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives.  The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI’s intramural Center for Cancer Research (CCR).  The dedicated units provide electron microscopy, protein characterization, protein expression, optical microscopy and nextGen sequencing. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research.  CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise. KEY ROLES/RESPONSIBILITIES We are seeking a highly motivated Research Associate II to join the newly established Single Cell Analysis Facility (SCAF) of the CCR at NCI.  The SCAF will house state of the art single cell sequencing technologies including 10xGenomics Chromium, BD Genomics Rhapsody, DEPPArray, and other emerging single cell technologies. This person will work under the guidance of SCAF senior staff to carry out single cell sequencing experiments.

  19. Institutional Support : Institute for Research on Political Economy in ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... of the next generation of teachers and researchers in political economy in Bénin and West Africa. IREEP has successfully integrated academic training and research activities. IREEP has been involved in a number of research projects spanning a wide range of topics (democracy, governance, education, health, energy).

  20. 78 FR 30933 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-23

    .... Time: 1:00 p.m. to 4:00 p.m. Agenda: To review and evaluate contract proposals. Place: National Cancer... Conference Call). Contact Person: Clifford W Schweinfest, Ph.D., Scientific Review Officer, Special Review... Committee: National Cancer Institute Special Emphasis Panel; Nanotech-Biosensor Platforms for Cancer. Date...

  1. National Cancer Institute Formulary: A Public-Private Partnership Providing Investigators Access to Investigational Anticancer Agents.

    Science.gov (United States)

    Cristofaro, J V; Ansher, S S; Zwiebel, J A; Ivy, P; Conley, B; Abrams, J S; Doroshow, J H

    2017-05-01

    As part of the White House Cancer Moonshot Initiative, the National Cancer Institute (NCI) has developed a drug formulary to provide investigational anticancer agents to the extramural research community. This article describes how the NCI Formulary functions, how researchers may apply for access to drugs in the formulary, and the NCI's initial goals for formulary participation. Approved investigators may apply for access to formulary agents at: https://nciformulary.cancer.gov. © 2016 American Society for Clinical Pharmacology and Therapeutics.

  2. 78 FR 8156 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... proposals. Place: Bethesda North Marriott Hotel & Conference Center, Montgomery County Conference Center... Institute, NIH, 6116 Executive Blvd., Suite 703, Room 7072, Bethesda, md 20892-8329, 301-594-1408, Stoicaa2...

  3. Institutional Support : Institute for Policy Analysis and Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    This grant from IDRC's Think Tank Initiative (TTI) will allow IPAR-Rwanda to strengthen its managerial and research capacity by means of a mentoring program for managers, researchers and support staff. This will include formulating a set of organizational goals and establishing a monitoring system to assess progress ...

  4. National Institute of Dental and Craniofacial Research

    Science.gov (United States)

    ... Mouth Burning Mouth Tooth Decay See All Oral Health Oral Complications of Systemic Diseases Cancer Treatment Developmental Disabilities Diabetes HIV/AIDS Order Free Publications English and Spanish ...

  5. Institutional Support : Makerere Institute of Social Research (MISR ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    This grant from IDRC's Think Tank Initiative (TTI) will provide MISR with the necessary core funding to expand its research capacity, increase its training activities, strengthen its organizational systems, formulate a long-term strategy, and establish a monitoring and evaluation system to assess progress made toward these ...

  6. Workshop: Creating Your Institutional Research Repository

    KAUST Repository

    Grenz, Daryl M.

    2016-11-08

    In 2002, the Scholarly Publishing and Academic Resources Coalition (SPARC) proposed the concept of an institutional repository to simultaneously disrupt and enhance the state of scholarly communications in the academic world. Thirteen years later, thousands of universities and other institutions have answered this call, but many more have not due to gaps in budgets, awareness and, most of all, practical guidance on creating an institutional repository. This workshop provides you with an essential primer on what it takes to establish a fully-functioning institutional repository. Every aspect of the process will be covered, including policies, procedures, staffing guidelines, workflows and repository technologies.

  7. Astronomy Legacy Project - Pisgah Astronomical Research Institute

    Science.gov (United States)

    Barker, Thurburn; Castelaz, Michael W.; Rottler, Lee; Cline, J. Donald

    2016-01-01

    Pisgah Astronomical Research Institute (PARI) is a not-for-profit public foundation in North Carolina dedicated to providing hands-on educational and research opportunities for a broad cross-section of users in science, technology, engineering and math (STEM) disciplines. In November 2007 a Workshop on a National Plan for Preserving Astronomical Photographic Data (2009ASPC,410,33O, Osborn, W. & Robbins, L) was held at PARI. The result was the establishment of the Astronomical Photographic Data Archive (APDA) at PARI. In late 2013 PARI began ALP (Astronomy Legacy Project). ALP's purpose is to digitize an extensive set of twentieth century photographic astronomical data housed in APDA. Because of the wide range of types of plates, plate dimensions and emulsions found among the 40+ collections, plate digitization will require a versatile set of scanners and digitizing instruments. Internet crowdfunding was used to assist in the purchase of additional digitization equipment that were described at AstroPlate2014 Plate Preservation Workshop (www.astroplate.cz) held in Prague, CZ, March, 2014. Equipment purchased included an Epson Expression 11000XL scanner and two Nikon D800E cameras. These digital instruments will compliment a STScI GAMMA scanner now located in APDA. GAMMA will be adapted to use an electroluminescence light source and a digital camera with a telecentric lens to achieve high-speed high-resolution scanning. The 1μm precision XY stage of GAMMA will allow very precise positioning of the plate stage. Multiple overlapping CCD images of small sections of each plate, tiles, will be combined using a photo-mosaic process similar to one used in Harvard's DASCH project. Implementation of a software pipeline for the creation of a SQL database containing plate images and metadata will be based upon APPLAUSE as described by Tuvikene at AstroPlate2014 (www.astroplate.cz/programs/).

  8. A Survey Data Quality Strategy: The Institutional Research Perspective

    Science.gov (United States)

    Liu, Qin

    2009-01-01

    This paper intends to construct a survey data quality strategy for institutional researchers in higher education in light of total survey error theory. It starts with describing the characteristics of institutional research and identifying the gaps in literature regarding survey data quality issues in institutional research. Then it is followed by…

  9. 77 FR 19674 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-04-02

    ... commercial property such as patentable material, and personal information concerning individuals associated... and evaluate grant applications. Place: Doubletree Hotel Bethesda, 8120 Wisconsin Avenue, Bethesda, MD... Institute Special Emphasis Panel; Innovative Molecular Analysis Technologies for Cancer (R21). Date: June 26...

  10. 78 FR 27974 - Proposed Collection; 60-Day Comment Request: National Cancer Institute (NCI) Alliance for...

    Science.gov (United States)

    2013-05-13

    ... Comment Request: National Cancer Institute (NCI) Alliance for Nanotechnology in Cancer Platform... project, contact: Dorothy Farrell, Center for Strategic Scientific Initiatives, Office of Cancer... Institute (NCI) Alliance for Nanotechnology in Cancer Platform Partnership Scientific Progress Reports, 0925...

  11. Research Associate | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Basic Science Program (BSP) pursues independent, multidisciplinary research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics. Research efforts and support are an integral part of the Center for Cancer Research (CCR) at the Frederick National Laboratory for Cancer Research (FNLCR). KEY ROLES/RESPONSIBILITIES - Research Associate III Dr. Zbigniew Dauter is the head investigator of the Synchrotron Radiation Research Section (SRRS) of CCR’s Macromolecular Crystallography Laboratory. The Synchrotron Radiation Research Section is located at Argonne National Laboratory, Argonne, Illinois; this is the site of the largest U.S. synchrotron facility. The SRRS uses X-ray diffraction technique to solve crystal structures of various proteins and nucleic acids of biological and medical relevance. The section is also specializing in analyzing crystal structures at extremely high resolution and accuracy and in developing methods of effective diffraction data collection and in using weak anomalous dispersion effects to solve structures of macromolecules. The areas of expertise are: Structural and molecular biology Macromolecular crystallography Diffraction data collection Dr. Dauter requires research support in these areas, and the individual will engage in the purification and preparation of samples, crystallize proteins using various techniques, and derivatize them with heavy atoms/anomalous scatterers, and establish conditions for cryogenic freezing. Individual will also participate in diffraction data collection at the Advanced Photon Source. In addition, the candidate will perform spectroscopic and chromatographic analyses of protein and nucleic acid samples in the context of their purity, oligomeric state and photophysical properties.

  12. The Undergraduate Research Resources at the Pisgah Astronomical Research Institute

    Science.gov (United States)

    Cline, J. Donald; Castelaz, Michael W.

    2016-01-01

    Pisgah Astronomical Research Institute (PARI), a former NASA tracking station located in western North Carolina, has been offering programs, campus, and instrument use for undergraduate research and learning experiences since 2000. Over these years, PARI has collaborated with universities and colleges in the Southeastern U.S. Sharing its campus with institutions of higher learning is a priority for PARI as part of its mission to "to providing hands-on educational and research opportunities for a broad cross-section of users in science, technology, engineering and math (STEM) disciplines."PARI is a 200 acre campus for environmental, earth, geological, physical, and astronomical sciences. For example, the PARI 26-m and 4.6-m radio telescopes are excellent for teaching electromagnetic theory, spectroscopy, atomic and molecular emission processes, and general physics and astronomy concepts. The PARI campus has lab and office space, data centers with high speed internet, distance learning capabilities, radio and optical telescopes, earth science sensors, housing and cafeteria.Also, the campus is in an excellent spot for environmental and biological sciences lab and classroom experiences for students. The campus has the capability to put power and Internet access almost anywhere on its 200 acre campus so experiments can be set up in a protected area of a national forest. For example, Earthscope operates a Plate Boundary Observatory sensor on campus to measure plate tectonic motion. And, Clemson University has an instrument measuring winds and temperatures in the Thermsophere. The use of thePARI campus is limited only by the creativity faculty to provide a rich educational environment for their students. An overview of PARI will be presented along with a summary of programs, and a summary of undergraduate research experiences over the past 15 years. Access to PARI and collaboration possibilities will be presented.

  13. Spacecraft computer technology at Southwest Research Institute

    Science.gov (United States)

    Shirley, D. J.

    1993-01-01

    Southwest Research Institute (SwRI) has developed and delivered spacecraft computers for a number of different near-Earth-orbit spacecraft including shuttle experiments and SDIO free-flyer experiments. We describe the evolution of the basic SwRI spacecraft computer design from those weighing in at 20 to 25 lb and using 20 to 30 W to newer models weighing less than 5 lb and using only about 5 W, yet delivering twice the processing throughput. Because of their reduced size, weight, and power, these newer designs are especially applicable to planetary instrument requirements. The basis of our design evolution has been the availability of more powerful processor chip sets and the development of higher density packaging technology, coupled with more aggressive design strategies in incorporating high-density FPGA technology and use of high-density memory chips. In addition to reductions in size, weight, and power, the newer designs also address the necessity of survival in the harsh radiation environment of space. Spurred by participation in such programs as MSTI, LACE, RME, Delta 181, Delta Star, and RADARSAT, our designs have evolved in response to program demands to be small, low-powered units, radiation tolerant enough to be suitable for both Earth-orbit microsats and for planetary instruments. Present designs already include MIL-STD-1750 and Multi-Chip Module (MCM) technology with near-term plans to include RISC processors and higher-density MCM's. Long term plans include development of whole-core processors on one or two MCM's.

  14. Meharry-Johns Hopkins Center for Prostate Cancer Research

    Science.gov (United States)

    2015-11-01

    questionnaire to assess their prostate cancer health seeking behavior. 15. SUBJECT TERMS Prostate cancer, Dietary risk factors, Lycopene, Genetic ... predisposition , African-Americans, Cancer research training, Quality of life, Community outreach, Recruiting study participants, Cell line inhibition...Institute (NCI) state cancer profiles, the mortality rate is almost three times that of CA men (73.9 per 100,000 AA / 25.6 per 100,000 C). Genetic and

  15. Institutional Support to Policy Research Organizations in India ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Institution. Center for Study of Science, Technology and Policy. Pays d' institution. India. Site internet. http://www.cstep.in ... Institution. (Chief, Administrative Services) for and on behalf of Centre for Policy Research Registered Society. Pays d' institution. India. Site internet. http://www.cprindia.org ...

  16. Statistical Analysis of Research Data | Center for Cancer Research

    Science.gov (United States)

    Recent advances in cancer biology have resulted in the need for increased statistical analysis of research data. The Statistical Analysis of Research Data (SARD) course will be held on April 5-6, 2018 from 9 a.m.-5 p.m. at the National Institutes of Health's Natcher Conference Center, Balcony C on the Bethesda Campus. SARD is designed to provide an overview on the general principles of statistical analysis of research data.  The first day will feature univariate data analysis, including descriptive statistics, probability distributions, one- and two-sample inferential statistics.

  17. 77 FR 5029 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2012-02-01

    ... Community; Cancer Drug Shortages: Economic, Regulatory, and Manufacturing Issues; The Role of the Cancer... security, NIH has instituted stringent procedures for entrance onto the NIH campus. All visitor vehicles, including taxicabs, hotel, and airport shuttles will be inspected before being allowed on campus. Visitors...

  18. Gaps in nutritional research among older adults with cancer.

    Science.gov (United States)

    Presley, Carolyn J; Dotan, Efrat; Soto-Perez-de-Celis, Enrique; Jatoi, Aminah; Mohile, Supriya G; Won, Elizabeth; Alibhai, Shabbir; Kilari, Deepak; Harrison, Robert; Klepin, Heidi D; Wildes, Tanya M; Mustian, Karen; Demark-Wahnefried, Wendy

    2016-07-01

    Nutritional issues among older adults with cancer are an understudied area of research despite significant prognostic implications for treatment side effects, cancer-specific mortality, and overall survival. In May of 2015, the National Cancer Institute and the National Institute on Aging co-sponsored a conference focused on future directions in geriatric oncology research. Nutritional research among older adults with cancer was highlighted as a major area of concern as most nutritional cancer research has been conducted among younger adults, with limited evidence to guide the care of nutritional issues among older adults with cancer. Cancer diagnoses among older adults are increasing, and the care of the older adult with cancer is complicated due to multimorbidity, heterogeneous functional status, polypharmacy, deficits in cognitive and mental health, and several other non-cancer factors. Due to this complexity, nutritional needs are dynamic, multifaceted, and dependent on the clinical scenario. This manuscript outlines the proceedings of this conference including knowledge gaps and recommendations for future nutritional research among older adults with cancer. Three common clinical scenarios encountered by oncologists include (1) weight loss during anti-cancer therapy, (2) malnutrition during advanced disease, and (3) obesity during survivorship. In this manuscript, we provide a brief overview of relevant cancer literature within these three areas, knowledge gaps that exist, and recommendations for future research. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. 77 FR 68136 - National Cancer Institute Amended; Notice of Meeting

    Science.gov (United States)

    2012-11-15

    ... Regency Bethesda Hotel, Old Georgetown Room, One Metro Center, Bethesda, MD 20814. The NCAB ad hoc... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute..., Building 31C, Wing C, Conference Room 10, 31 Center Drive, Bethesda, MD 20892 which was published in the...

  20. Postdoctoral Fellows | Center for Cancer Research

    Science.gov (United States)

    The Oncogenomics section of the Genetics Branch is a multidisciplinary and interdisciplinary translational research programmatic effort with the goal of utilizing genomics to develop novel immunotherapies for cancer. Our group is applying high throughput applied genomics methods including single cell RNAseq, single cell TCR sequencing, DNA sequencing, CRISPR/Cas9, bioinformatics combined with T cell based therapeutics to identify and develop novel immunotherapeutics for human cancer. We work with other investigators within the intramural program as well as industrial and pharmaceutical partners to rapidly translate our findings to the clinic. The program takes advantage of the uniqueness of the National Cancer Institute, (NCI), Center for Cancer Research (CCR) intramural program in that it spans high-risk basic discovery research in immunology, genomics and tumor biology, through preclinical translational research, to paradigm-shifting clinical trials. The position is available immediately. The appointment duration is up to 5 years. Stipends are commensurate with education and experience. Additional information can be found on Dr. Khan’s profile page: https://ccr.cancer.gov/Genetics-Branch/javed-khan

  1. 76 FR 20693 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2011-04-13

    ... special assistance, such as sign language interpretation or other reasonable accommodations, should notify... Dialogue, Nonprofit Conveners Driving Implementation of Research Outcomes, Barriers to Implementation of Research Outcomes, Presentations Highlighting Local Academic Research in Cancer. Place: Rizzo Conference...

  2. UNLV Information Science Research Institute. Quarterly progress report

    International Nuclear Information System (INIS)

    Nartker, T.A.

    1994-01-01

    This document summarizes the activities and progress for the 1994 Fall quarter for the UNLV Information Science Research Institute. Areas covered include: Symposium activity, Staff activity, Document analysis program, Text-retrieval program, and Institute activity

  3. Institute for Advanced Learning and Research names new executive director

    OpenAIRE

    Virginia Tech News

    2008-01-01

    Virginia Tech's Institute for Advanced Learning and Research has named Liam E. Leightley as executive director, effective Oct. 6, 2008, according to Mike Henderson, chair of the institute's board of trustees.

  4. Institute of Nuclear Physics, mission and scientific research activities

    International Nuclear Information System (INIS)

    Zoto, J.; Zaganjori, S.

    2004-01-01

    The Institute of Nuclear Physics (INP) was established in 1971 as a scientific research institution with main goal basic scientific knowledge transmission and transfer the new methods and technologies of nuclear physics to the different economy fields. The organizational structure and main research areas of the Institute are described. The effects of the long transition period of the Albanian society and economy on the Institution activity are also presented

  5. Transforming Welfare Institutions through Action Research

    DEFF Research Database (Denmark)

    Andersen, John; Bilfeldt, Annette

    Abstract til ALARA 9th Action Learning Action Research and 13th Participatory Action Research World Congress, South Africa from 4 – 7 November 2015 Pretoria, Sydafrika......Abstract til ALARA 9th Action Learning Action Research and 13th Participatory Action Research World Congress, South Africa from 4 – 7 November 2015 Pretoria, Sydafrika...

  6. Prostate Cancer Research Training Program

    Science.gov (United States)

    2017-09-01

    the research program by each mentor will certainly produce important research findings, aided in part by the summer research of...our "translational" research in the form of clinical trials of our adenovirus vaccine in men with prostate cancer. Important in these trials is the ...epidemiology, and treatment. Living in Iowa City for the Summer Housing and Meals - All students will be housed in the one of the residence halls on the

  7. 77 FR 55848 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2012-09-11

    ... Clinical Trials and Strategic Planning Subcommittee. Date: September 24, 2012. Time: 5 p.m. to 6 p.m... Trials Strategic Planning Subcommittee. Dial in number: 1-866-652-9542 and Passcode: 4596704. Place... Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397...

  8. 78 FR 5190 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2013-01-24

    ... Clinical Trials and Strategic Planning Subcommittee. Date: February 25, 2013. Time: 5:00 p.m. to 6:00 p.m... Trials Strategic Planning Subcommittee. Dial in number: 1-866-652-9542 and Passcode: 4596704. Place... Research; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396...

  9. 77 FR 36564 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2012-06-19

    ... Prevention Method: State of the, Science and Evidence. Place: Hilton San Francisco Financial District, 750... applicable, the business or professional affiliation of the interested person. Information is also available... Research; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396...

  10. Accountability Principles for Research Institutes | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Claims of democratic deficits and crises of legitimacy have prompted growing interest in accountability on the part of national and international institutions. ... IDRC's support of BetterEvaluation, an international collaboration to improve evaluation practice and theory, has resulted in an online guide for an often overlooked ...

  11. Information Science Research Institute quarterly progress report

    Energy Technology Data Exchange (ETDEWEB)

    Nartker, T.A.

    1995-09-30

    Subjects studied include optical character recognition (OCR), text retrieval, and document analysis. This report discusses the OCR test system and the text retrieval program. Staff and institute activities are given. Appendices give the ISRI methodology for preparing ground-truth test data and the test of OCR systems using DOE documents.

  12. Cancer Trends: Influencing Care and Research Priorities

    Science.gov (United States)

    Many of the trends being seen in cancer are changing how we view cancer and how we address it, from prompting research to identify the underlying causes of cancers increasing in incidence to informing research on treatment and prevention.

  13. The national cancer institute (NCI) and cancer biology in a 'post genome world'

    International Nuclear Information System (INIS)

    Klausner, Richard D.

    1996-01-01

    The National Cancer Institute (NCI) exists to reduce the burden of all cancers through research and discovery. Extensive restructuring of the NCI over the past year has been aimed at assuring that the institution functions in all ways to promote opportunities for discovery in the laboratory, in the clinic, and in the community. To do this well requires the difficult and almost paradoxical problem of planning for scientific discovery which, in turn is based on the freedom to pursue the unanticipated. The intellectual and structural landscape of science is changing and it places new challenges, new demands and new opportunities for facilitating discovery. The nature of cancer as a disease of genomic instability and of accumulated genetic change, coupled with a possibility of the development of new technologies for reading, utilizing, interpreting and manipulating the genome of single cells, provides unprecedented opportunities for a new type of high through-put biology that will change the nature of discovery, cancer detection, diagnosis, prognosis, therapeutic decision-making and therapeutic discovery. To capture these new opportunities will require attention to be paid to integrate the development of technology and new scientific discoveries with the ability to apply advances rapidly and efficiently through clinical trials

  14. Cancer research meets evolutionary biology.

    Science.gov (United States)

    Pepper, John W; Scott Findlay, C; Kassen, Rees; Spencer, Sabrina L; Maley, Carlo C

    2009-02-01

    There is increasing evidence that Darwin's theory of evolution by natural selection provides insights into the etiology and treatment of cancer. On a microscopic scale, neoplastic cells meet the conditions for evolution by Darwinian selection: cell reproduction with heritable variability that affects cell survival and replication. This suggests that, like other areas of biological and biomedical research, Darwinian theory can provide a general framework for understanding many aspects of cancer, including problems of great clinical importance. With the availability of raw molecular data increasing rapidly, this theory may provide guidance in translating data into understanding and progress. Several conceptual and analytical tools from evolutionary biology can be applied to cancer biology. Two clinical problems may benefit most from the application of Darwinian theory: neoplastic progression and acquired therapeutic resistance. The Darwinian theory of cancer has especially profound implications for drug development, both in terms of explaining past difficulties, and pointing the way toward new approaches. Because cancer involves complex evolutionary processes, research should incorporate both tractable (simplified) experimental systems, and also longitudinal observational studies of the evolutionary dynamics of cancer in laboratory animals and in human patients. Cancer biology will require new tools to control the evolution of neoplastic cells.

  15. Institutional Support : Centre for Research and Technology ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    year-old science and technology research centre at Maseno University in western Kenya. The Centre focuses on science and technology research to influence both national policies and development practices at the community level. Currently ...

  16. Institutional Support : Research on Poverty Alleviation (REPOA ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    -established and well-managed independent policy research organization with a record of producing high-quality, policy-relevant research results. REPOA is experiencing rapid growth in the demand for its services. This grant from IDRC's ...

  17. Research Institute for Autonomous Precision Guided Systems

    National Research Council Canada - National Science Library

    Sforza, Pasquale

    2003-01-01

    The aim of this project is to leverage the manpower resources dedicated to basic research in technologies relevant to autonomous precision systems at the Air Force Research Laboratory Munitions Directorate (AFRL/MN...

  18. National Institute on Disability and Rehabilitation Research

    Science.gov (United States)

    ... and Rehabilitation Research (NIDILRR). NIDILRR Legislation & Policy The Creation of NIDILRR and Its Legislative Mandate The National ... These entities are then supposed to use this money to plan and conduct research, demonstration projects, training ...

  19. Institutional Support : Economic and Social Research Foundation ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Economic and Social Research Foundation (ESRF) is an independent research organization that was registered in Tanzania in October 1992. Recent uncertainty regarding the delivery modality of its principal source of funding (the African Capacity Building Foundation) led to a massive departure of senior researchers, ...

  20. TTI Phase 2 Institutional Support: Economic and Social Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    TTI Phase 2 Institutional Support: Economic and Social Research Foundation. This funding will help strengthen the Economic and Social Research Foundation's (ESRF) role as a credible public policy institution in Tanzania by enhancing its ability to provide high-quality, influential, and policy-relevant research. About the ...

  1. Use of Students as Research Subjects: Institutional Responsibility.

    Science.gov (United States)

    Smith, Deborah L.; And Others

    1991-01-01

    A brief history of research involving humans is followed by discussion of the use of students in university research projects and institutional responsibility to students and the public. Institutions are encouraged to incorporate specific controls into research policies to avoid legal problems in the areas of contract theory, fiduciary…

  2. Nanotechnology: Emerging Developments and Early Detection of Cancer. A Two-Day Workshop Sponsored by the National Cancer Institute and the National Institute of Standards and Technology, August 30–31 2001, on the National Institute of Standards and Technology Campus, Gaithersburg, MD, USA

    Science.gov (United States)

    Zullo, Steven J.; Srivastava, Sudhir; Looney, J. Patrick; Barker, Peter E.

    2002-01-01

    A recent meeting jointly sponsored by the National Cancer Institute (NCI) and National Institute of Standards and Technology (NIST) brought together researchers active in nanotechnology and cancer molecular biology to discuss and evaluate the interface between disciplines. Emerging areas where nanotechnologies may impact cancer prevention and early cancer detection were elaborated by key researchers who catalyzed interdisciplinary dialogue aimed at fostering cross-discipline communications and future collaboration. PMID:12590168

  3. Information Security Issues in Higher Education and Institutional Research

    Science.gov (United States)

    Custer, William L.

    2010-01-01

    Information security threats to educational institutions and their data assets have worsened significantly over the past few years. The rich data stores of institutional research are especially vulnerable, and threats from security breaches represent no small risk. New genres of threat require new kinds of controls if the institution is to prevent…

  4. Disparities in Geographic Accessibility of National Cancer Institute Cancer Centers in the United States.

    Science.gov (United States)

    Xu, Yanqing; Fu, Cong; Onega, Tracy; Shi, Xun; Wang, Fahui

    2017-11-11

    The National Cancer Institute (NCI) Cancer Centers form the backbone of the cancer care system in the United States since their inception in the early 1970s. Most studies on their geographic accessibility used primitive measures, and did not examine the disparities across urbanicity or demographic groups. This research uses an advanced accessibility method, termed "2-step floating catchment area (2SFCA)" and implemented in Geographic Information Systems (GIS), to capture the degree of geographic access to NCI Cancer Centers by accounting for competition intensity for the services and travel time between residents and the facilities. The results indicate that urban advantage is pronounced as the average accessibility is highest in large central metro areas, declines to large fringe metro, medium metro, small metro, micropolitan and noncore rural areas. Population under the poverty line are disproportionally concentrated in lower accessibility areas. However, on average Non-Hispanic White have the lowest geographic accessibility, followed by Hispanic, Non-Hispanic Black and Asian, and the differences are statistically significant. The "reversed racial disadvantage" in NCI Cancer Center accessibility seems counterintuitive but is consistent with an influential prior study; and it is in contrast to the common observation of co-location of concentration of minority groups and people under the poverty line.

  5. Strengthening Institutional Research Administration in Uganda: A Case Study on Developing Collaborations among Academic and Research Institutions

    Science.gov (United States)

    Kakande, Nelson; Namirembe, Regina; Kaye, Dan K.; Mugyenyi, Peter N.

    2012-01-01

    Despite the presence of several funded research projects at academic and research institutions in sub-Saharan Africa, the quality of the pre/post grant award process in these institutions is inadequate. There is a need to strengthen research administration through infrastructural, organizational, and human resource development to match the dynamic…

  6. Japanese Research Institutes Funded by Private Corporations.

    Science.gov (United States)

    1983-12-01

    vibration, and noise are also items of interest to the company. With a view toward be- er economics of investment and operations, the Center is...28% Cake, doughnut mixes, and others ......... 11% 105 R & D ACTIVITIES The Central Research Laboratory, in medical research studies, is...energy. The laboratories are trying to establish economical techniques in producing materials other than iron, such as titanium, carbon, and amorphous

  7. Forschungszentrum Rossendorf, Institute of Safety Research. Annual report 2004

    International Nuclear Information System (INIS)

    Weiss, F.P.; Rindelhardt, U.

    2005-01-01

    The Institute of Safety Research (ISR) is one of the six Research Institutes of Forschungszentrum Rossendorf e.V. (FZR e.V.) which is a member institution of the Wissenschaftsgemeinschaft Gottfried Wilhelm Leibniz (Leibniz Association). Together with the Institute of Radiochemistry, ISR constitutes the research programme ''Safety and Environment'' which is one from three scientific programmes of FZR. In the framework of this research programme, the institute is responsible for the two subprogrammes ''Plant and Reactor Safety'' and ''Thermal Fluid Dynamics'', respectively. We also provide minor contributions to the sub-programme ''Radio-Ecology''. Moreover, with the development of a pulsed photo-neutron source at the radiation source ELBE (Electron linear accelerator for beams of high brilliance and low emittance), we are involved in a networking project carried out by the FZR Institute of Nuclear and Hadron Physics, the Physics Department of TU Dresden, and ISR. (orig.)

  8. Physician Assistant | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  9. Guidelines for an environmental code of ethics for research institutions

    International Nuclear Information System (INIS)

    Gardusi, Claudia; Aquino, Afonso Rodrigues de

    2009-01-01

    The purpose of this work is to reflect about actions that may contribute to the creation of mechanisms to protect the environment in the development of research projects at research institutions, specifically the Nuclear and Energy Research Institute - IPEN. A brief review of part of the ethical values applied to the process of scientific development during the old, medieval and modern periods is presented, showing the split of the nature ethical principles. It is also reported an overview of the creation of codes of ethics applied to research institutions. Moreover, criteria are presented to settle guidelines to protect the environment during the development of research projects. (author)

  10. NIH's National Institute of Nursing Research Is Changing Lives

    Science.gov (United States)

    ... Current Issue Past Issues NIH's National Institute of Nursing Research Is Changing Lives Past Issues / Spring 2008 Table ... on. From childbirth to end-of-life care, nursing research is aimed at helping patients across the entire ...

  11. The Future of Prostate Cancer Research and Treatment

    Science.gov (United States)

    On January 12, 2017 prostate cancer experts William Dahut, M.D. of the National Cancer Institute and Dr. Heather Cheng, M.D. of the University of Washington had a vibrant discussion about current and future research areas and treatment options for prostate cancer. The panel was moderated by Ana Fadich, MPH, CHES Vice President at Men’s Health of the Men's Health Network.

  12. Research Review of the Institute of African Studies

    African Journals Online (AJOL)

    Please note: As of 2013 the Research Review of the Institute of African Studies is now publishing under the title Contemporary Journal of African Studies. You can view the CJAS pages on AJOL here: http://www.ajol.info/index.php/contjas/index. The Research Review of the Institute of African Studies at the University of ...

  13. THE CONTRIBUTION OF RESEARCH INSTITUTES IN EUREKA PROJECTS

    NARCIS (Netherlands)

    VANROSSUM, W; CABO, PG

    1995-01-01

    Technological cooperation between industrial firms and research institutes is studied at the project level. The various forms of cooperation, and the instances in which they are advantageous, are discussed. The authors then focus on situations in which the research institute acts as 'knowledge

  14. Developing a Policy on Institutional Research for Black Hawk College.

    Science.gov (United States)

    Quayle, Thomas; Stevens, Mary A.

    In order to study the general objectives, methods, and provisions for institutional research in the community college, this document surveys the pertinent literature and reviews institutional research practices at selected community colleges. In general, three basic governance structure models are identified which represent varying relationships…

  15. Open Access Publishing in Indian Premier Research Institutions

    Science.gov (United States)

    Bhat, Mohammad Hanief

    2009-01-01

    Introduction: Publishing research findings in open access journals is a means of enhancing visibility and consequently increasing the impact of publications. This study provides an overview of open access publishing in premier research institutes of India. Method: The publication output of each institution from 2003 to 2007 was ascertained through…

  16. Research Productivity and Its Policy Implications in Higher Education Institutions

    Science.gov (United States)

    Quimbo, Maria Ana T.; Sulabo, Evangeline C.

    2014-01-01

    Responding to the Commission on Higher Education's development plan of enhancing research culture among higher education institutions, this study was conducted to analyze the research productivity of selected higher education institutions. It covered five state universities in the Philippines where a total of 377 randomly selected faculty members…

  17. National Nuclear Research Institute (NNRI) - Annual Report 2015

    International Nuclear Information System (INIS)

    2015-01-01

    The 2015 report of the National Nuclear Research Institute (NNRI) of the Ghana Atomic Energy Commission (GAEC) lists various programmes undertaken by the Institute under the following headings: Water resources programme, Energy Research programme, Environmental and Health Safety Programme, Digital Instrumentation programme, Nuclear Applications and Materals programme and Radiation Occupational safety programme. Also, included are abstracts of publications and technical reports.

  18. Nebraska Prostate Cancer Research Program

    Science.gov (United States)

    2015-10-01

    Khan then phoned Dr. Lin regarding the conclusion of meeting with students’ evaluation and expressed students’ positive attitude toward research...nitrocellulose membrane, membranes were blocked with 5% non-fat milk Novel Imidazopyridines in Castration-Resistant Prostate Cancer PLOS ONE | DOI

  19. Testicular Cancer Survivorship: Research Strategies and Recommendations

    Science.gov (United States)

    Beard, Clair; Allan, James M.; Dahl, Alv A.; Feldman, Darren R.; Oldenburg, Jan; Daugaard, Gedske; Kelly, Jennifer L.; Dolan, M. Eileen; Hannigan, Robyn; Constine, Louis S.; Oeffinger, Kevin C.; Okunieff, Paul; Armstrong, Greg; Wiljer, David; Miller, Robert C.; Gietema, Jourik A.; van Leeuwen, Flora E.; Williams, Jacqueline P.; Nichols, Craig R.; Einhorn, Lawrence H.; Fossa, Sophie D.

    2010-01-01

    Testicular cancer represents the most curable solid tumor, with a 10-year survival rate of more than 95%. Given the young average age at diagnosis, it is estimated that effective treatment approaches, in particular, platinum-based chemotherapy, have resulted in an average gain of several decades of life. This success, however, is offset by the emergence of considerable long-term morbidity, including second malignant neoplasms, cardiovascular disease, neurotoxicity, nephrotoxicity, pulmonary toxicity, hypogonadism, decreased fertility, and psychosocial problems. Data on underlying genetic or molecular factors that might identify those patients at highest risk for late sequelae are sparse. Genome-wide association studies and other translational molecular approaches now provide opportunities to identify testicular cancer survivors at greatest risk for therapy-related complications to develop evidence-based long-term follow-up guidelines and interventional strategies. We review research priorities identified during an international workshop devoted to testicular cancer survivors. Recommendations include 1) institution of lifelong follow-up of testicular cancer survivors within a large cohort setting to ascertain risks of emerging toxicities and the evolution of known late sequelae, 2) development of comprehensive risk prediction models that include treatment factors and genetic modifiers of late sequelae, 3) elucidation of the effect(s) of decades-long exposure to low serum levels of platinum, 4) assessment of the overall burden of medical and psychosocial morbidity, and 5) the eventual formulation of evidence-based long-term follow-up guidelines and interventions. Just as testicular cancer once served as the paradigm of a curable malignancy, comprehensive follow-up studies of testicular cancer survivors can pioneer new methodologies in survivorship research for all adult-onset cancer. PMID:20585105

  20. Institutional review boards' attitudes towards remuneration in paediatric research

    DEFF Research Database (Denmark)

    Flege, Marius M; Thomsen, Simon F

    2017-01-01

    Remuneration in paediatric research poses an ethical dilemma. Too large a sum might cause parents to enrol their children in research projects with no benefit for the child, whereas too modest a sum might hamper recruitment. The institutional review boards have the responsibility to only approve...... remuneration in paediatric trials with ethically sound research plans. However, little is known about which factors influence institutional review boards' evaluation of remuneration in paediatric research....

  1. Institutional Support : Applied and Theoretical Economic Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Groupe de recherche en économie appliquée et théorique (GREAT) is a nine-year-old independent nonprofit research centre located in Bamako, Mali. The centre has made a significant contribution to policy, mainly due to a dynamic director who has spearheaded the effort almost singlehandedly. This grant from ...

  2. Mainstreaming Community-based Research: Institutional ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    University of Victoria Professor Budd Hall, UNESCO Chair in Community-Based Research and Social Responsibility in Higher Education, will coordinate the project. A coalition of regional networks will implement it. Participating networks include the Global University Network for Innovation (Spain), the Talloires Network, ...

  3. Radiant Research. Institute for Energy Technology 1948-98

    International Nuclear Information System (INIS)

    Njoelstad, Olav

    1999-01-01

    Institutt for Atomenergi (IFA), or Institute for Atomic Energy, at Kjeller, Norway, was founded in 1948. The history of the institute as given in this book was published in 1999 on the occasion of the institute's 50th anniversary. The scope of the institute was to do research and development as a foundation for peaceful application of nuclear energy and radioactive substances in Norway. The book tells the story of how Norway in 1951 became the first country after the four superpowers and Canada to have its own research reactor. After the completion of the reactor, the institute experienced a long and successful period and became the biggest scientific and technological research institute in Norway. Three more reactors were built, one in Halden and two at Kjeller. Plans were developed to build nuclear powered ships and nuclear power stations. It became clear, however, in the 1970s, that there was no longer political support for nuclear power in Norway, and it was necessary for the institute to change its research profile. In 1980, the institute changed its name to Institutt for energiteknikk (IFE), or Institute for energy technology, to signal the broadened scope. The book describes this painful but successful readjustment and shows how IFE in the 1980s and 1990s succeeded in using its special competence from the nuclear field to establish special competence in new research fields with great commercial potential

  4. 76 FR 11800 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-03-03

    ... Emphasis Panel; Biosensors for Early Cancer Detection and Risk Assessment. Date: March 29, 2011. Time: 2 p.m. to 5 p.m. Agenda: To review and evaluate contract proposals. Place: National Institutes of Health...: Lalita D. Palekar, PhD, Scientific Review Officer, Special Review and Logistics Branch, Division of...

  5. The Regina Elena National Cancer Institute process of accreditation according to the standards of the Organisation of European Cancer Institutes.

    Science.gov (United States)

    Canitano, Stefano; Di Turi, Annunziata; Caolo, Giuseppina; Pignatelli, Adriana C; Papa, Elena; Branca, Marta; Cerimele, Marina; De Maria, Ruggero

    2015-01-01

    The accreditation process is, on the one hand, a tool used to homogenize procedures, rendering comparable and standardized processes of care, and on the other, a methodology employed to develop a culture of quality improvement. Although not yet proven by evidence-based studies that health outcomes improve as a result of an accreditation to excellence, it is undeniable that better control of healthcare processes results in better quality and safety of diagnostic and therapeutic pathways. The Regina Elena National Cancer Institute underwent the accreditation process in accordance with the standards criteria set by the Organisation of European Cancer Institutes (OECI), and it has recently completed the process, acquiring its designation as a Comprehensive Cancer Center (CCC). This was an invaluable opportunity for the Regina Elena Institute to create a more cohesive environment, to widely establish a culture of quality, to implement an institutional information system, and to accelerate the process of patient involvement in strategic decisions. The steps of the process allowed us to evaluate the performance and the organization of the institute and put amendments in place designed to be adopted through 26 improvement actions. These actions regarded several aspects of the institute, including quality culture, information communication technology system, care, clinical trials unit, disease management team, nursing, and patient empowerment and involvement. Each area has a timeline. We chose to present the following 3 improvement actions: clinical trial center, computerized ambulatory medical record, and centrality of patient and humanization of clinical pathway.

  6. Leveraging National Cancer Institute Programmatic Collaboration for Uterine Cervix Cancer Patient Accrual in Puerto Rico

    Directory of Open Access Journals (Sweden)

    Charles A. Kunos

    2018-04-01

    Full Text Available Women in the U.S. Commonwealth of Puerto Rico (PR have a higher age-adjusted incidence rate for uterine cervix cancer than the U.S. mainland as well as substantial access and economic barriers to cancer care. The National Cancer Institute (NCI funds a Minority/Underserved NCI Community Oncology Research Program in PR (PRNCORP as part of a national network of community-based health-care systems to conduct multisite cancer clinical trials in diverse populations. Participation by the PRNCORP in NCI’s uterine cervix cancer clinical trials, however, has remained limited. This study reports on the findings of an NCI site visit in PR to assess barriers impeding site activation and accrual to its sponsored gynecologic cancer clinical trials. Qualitative, semi-structured individual, and group interviews were conducted at six PRNCORP-affiliated locations to ascertain: long-term trial accrual objectives; key stakeholders in PR that address uterine cervix cancer care; key challenges or barriers to activating and to enrolling patients in NCI uterine cervix cancer treatment trials; and resources, policies, or procedures in place or needed on the island to support NCI-sponsored clinical trials. An NCI-sponsored uterine cervix cancer radiation–chemotherapy intervention clinical trial (NCT02466971, already activated on the island, served as a test case to identify relevant patient accrual and site barriers. The site visit identified five key barriers to accrual: (1 lack of central personnel to coordinate referrals for treatment plans, medical tests, and medical imaging across the island’s clinical trial access points; (2 patient insurance coverage; (3 lack of a coordinated brachytherapy schedule at San Juan-centric service providers; (4 limited credentialed radiotherapy machines island-wide; and (5 too few radiology medical physicists tasked to credential trial-specified positron emission tomography scanners island-wide. PR offers a unique opportunity to

  7. Differentiated Thyroid Cancer Multidisciplinary Management at the Colombian National Cancer Institute

    International Nuclear Information System (INIS)

    Garavito, Gloria; Llamas O, Augusto; Cadena, Enrique; De Los Reyes, Amelia

    2009-01-01

    Thyroid cancer is the most common malignant disease of the endocrine system. Two hundred and twenty-one new cases were diagnosed at the National Cancer Institute of Colombia (NCI) in 2006, roughly 4% of all new cancer cases. Weekly multidisciplinary decision-making meetings on thyroid cancer management have been held at the NCI since 1994. This article covers the body of knowledge gathered through 14 years of interdisciplinary collaboration where experience has been combined with the best available evidence.

  8. Breast Cancer Research at NASA

    Science.gov (United States)

    1998-01-01

    NASA's Marshall Space Flight Center (MSFC) is sponsoring research with Bioreactors, rotating wall vessels designed to grow tissue samples in space, to understand how breast cancer works. This ground-based work studies the growth and assembly of human mammary epithelial cells (HMEC) from breast cancer susceptible tissue. Radiation can make the cells cancerous, thus allowing better comparisons of healthy vs. tunourous tissues. Here, two High-Aspect Ratio Vessels turn at about 12 rmp to keep breast tissue constructs suspended inside the culture media. Syringes allow scientists to pull for analysis during growth sequences. The tube in the center is a water bubbler that dehumidifies the air to prevent evaporation of the media and thus the appearance of destructive bubbles in the bioreactor.

  9. Survey of Policies and Guidelines on Antioxidant Use for Cancer Prevention, Treatment, and Survivorship in North American Cancer Centers: What Do Institutions Perceive as Evidence?

    Science.gov (United States)

    Hong, Gyeongyeon; White, Jennifer; Zhong, Lihong; Carlson, Linda E

    2015-07-01

    Health care policies and guidelines that are clear and consistent with research evidence are important for maximizing clinical outcomes. To determine whether cancer centers in Canada and the United States had policies and/or guidelines about antioxidant use, and whether policies were aligned with the evidence base, we reviewed current research evidence in the field, and we undertook a survey of the policies and guidelines on antioxidant use at cancer institutions across North America. A survey of policies and guidelines on antioxidant use and the development and communication of the policies and guidelines was conducted by contacting cancer institutions in North America. We also conducted a Website search for each institution to explore any online resources. Policies and guidelines on antioxidant use were collected from 78 cancer institutions. Few cancer institutions had policies (5%) but most provided guidelines (69%). Antioxidants from diet were generally encouraged at cancer institutions, consistent with the current research evidence. In contrast, specific antioxidant supplements were generally not recommended at cancer institutions. Policies and guidelines were developed using evidence-based methods (53%), by consulting another source (35%), or through discussions/conference (26%), and communicated mainly through online resources (65%) or written handouts (42%). For cancer institutions that had no policy or guideline on antioxidants, lack of information and lack of time were the most frequently cited reasons. Policies and guidelines on antioxidants from diet were largely consistent with the research evidence. Policies and guidelines on antioxidant supplements during treatment were generally more restrictive than the research evidence might suggest, perhaps due to the specificity of results and the inability to generalize findings across antioxidants, adding to the complexity of their optimal and safe use. Improved communication of comprehensive research

  10. Chinese TEFL Academics' Perceptions about Research: An Institutional Case Study

    Science.gov (United States)

    Bai, Li; Millwater, Jan

    2011-01-01

    Research capacity building has become a prominent theme in higher education institutions in China, as across the world. However, Chinese TEFL (Teaching English as a Foreign Language) academics' research capacity has been quite limited. In order to build their research capacity, it is necessary to understand their perceptions about research. This…

  11. Radiological and Medical Sciences Research Institute (RAMSRI) - Annual Report 2015

    International Nuclear Information System (INIS)

    2015-01-01

    The Radiological and Medical Sciences Research Institute (RAMSRI) is the fourth Research and Development Institute of the Ghana Atomic Energy Commission (GAEC), undertaking research in human health and nutrition. This annual report covers the major activities undertaken by RAMSRI for the year 2015. The activities are grouped under the following headings: Establishment; Personnel and Organisation; Major Activities of Centres; Ongoing IAEA TC Projects; Human Resource Development; IAEA Coordinated Meetings Hosted; Publications; Achievements; Challenges; Projections for the Year 2016; and Recommendations.

  12. The law for the Japan Atomic Energy Research Institute

    International Nuclear Information System (INIS)

    1985-01-01

    The Act for Japan Atomic Energy Research Institute has been promulgated anew. Contents are the following : general rules, officials, advisors and personnel, duties, financial affairs and accounts, supervision, miscellaneous rules, penal provisions, and additional rules. (In the additional rules, the merger into JAERI of Japan Nuclear Ship Research and Development Agency is treated.) Japan Atomic Energy Research Institute conducts research etc. for the development of atomic energy comprehensively and efficiently, thereby contributing to the promotion of atomic energy research, development and utilization, according to the Atomic Energy Fundamental Act. Duties are atomic energy basic and application research, reactor relation, training of the personnel, RIs relation, etc. (Mori, K.)

  13. Gastrointestinal Tumor Board: An Evolving Experience in Tehran Cancer Institute

    Directory of Open Access Journals (Sweden)

    Peiman Haddad

    2013-04-01

    Full Text Available Gastrointestinal (GI cancers are a significant source of morbidity and mortality in Iran, with stomach adenocarcinoma as the most common cancer in men and the second common cancer in women. Also, some parts of Northern Iran have one of the highest incidences of esophageal cancer in the world. Multi-disciplinary organ-based joint clinics and tumor boards are a well-recognized necessity for modern treatment of cancer and are routinely utilized in developed countries, especially in major academic centres. But this concept is relatively new in developing countries, where cancer treatment centres are burdened by huge loads of patients and have to cope with a suboptimum availability of resources and facilities. Cancer Institute of Tehran University of Medical Sciences is the oldest and the only comprehensive cancer treatment centre in Iran, with a long tradition of a general tumor board for all cancers. But with the requirements of modern oncology, there has been a very welcome attention to sub-specialized organ-based tumor boards and joint clinics here in the past few years. Considering this, we started a multi-disciplinary tumor board for GI cancers in our institute in early 2010 as the first such endeavor here. We hereby review this 2-year evolving experience. The process of establishment of a GI tumor board, participations from different oncology disciplines and related specialties, the cancers presented and discussed in the 2 years of this tumor board, the general intents of treatment for the decisions made and the development of interest in this tumor board among the Tehran oncology community will be reviewed. The GI tumor board of Tehran Cancer Institute started its work in January 2010, with routine weekly sessions. A core group of 2 physicians from each surgical, radiation and medical oncology departments plus one gastroenterologist, GI pathologist and radiologist was formed, but participation from all interested physicians was encouraged. An

  14. Undergraduate cancer training program for underrepresented students: findings from a minority institution/cancer center partnership.

    Science.gov (United States)

    Coronado, Gloria D; O'Connell, Mary A; Anderson, Jennifer; Löest, Helena; Ogaz, Dana; Thompson, Beti

    2010-03-01

    Students from racially/ethnically diverse backgrounds are underrepresented in graduate programs in biomedical disciplines. One goal of the Minority Institution/Cancer Center partnership between New Mexico State University (NMSU) and the Fred Hutchinson Cancer Research Center (FHCRC) is to expand the number of underrepresented students who are trained in cancer research. As part of the collaboration, a summer internship program has been organized at the FHCRC. The program runs for 9 weeks and involves mentored research, research seminars, coffee breaks, social activities, and a final poster session. This study examined the graduate school attendance rates of past interns, explored interns' perceptions of the training program, and identified ways to improve the program. Thirty undergraduate students enrolled at NMSU participated in the internship program from 2002 to 2007 and telephone interviews were conducted on 22 (73%) of them. One-third of the students were currently in graduate school (32%); the remaining were either working (36%), still in undergraduate school (27%), or unemployed and not in school (5%). Students rated highly the following aspects of the program: mentored research, informal time spent with mentors, and research seminars. Students also reported the following activities would further enhance the program: instruction on writing a personal statement for graduate school and tips in choosing an advisor. Students also desired instruction on taking the GRE/MCAT, receiving advice on selecting a graduate or professional school, and receiving advice on where to apply. These findings can inform the design of internship programs aimed at increasing rates of graduate school attendance among underrepresented students.

  15. Administrative Assistant | Center for Cancer Research

    Science.gov (United States)

    We are looking for a pleasant, organized, dependable person to serve as an administrative assistant at the National Cancer Institute on the campus of the National Institutes of Health (NIH).  Work supports a busy clinical program in the world’s largest dedicated research hospital patients call the “House of Hope.”  Tasks involve calendar management, arranging travel, scheduling conferences and meetings, drafting and handling correspondence, timekeeping, placing purchase requests, office property management, greeting visitors, and office work, such as copying, filing, and scanning.  Ability to work with basic computer office software (such as Word, Excel, and PowerPoint) required. Some administrative experience, including calendar management preferred.  Full-time position, business hours. NIH is metro accessible.

  16. Media | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The Office of Cancer Clinical Proteomics Research (OCCPR) is committed to providing the media with timely and accurate information.  This section offers key resources for patients, cancer researchers, physicians, and media professionals.

  17. Strengthening the Cancer Research Enterprise - Annual Plan

    Science.gov (United States)

    NCI's expanding infrastructure, support for scientists at every career stage, and funding of small business innovation enables discoveries that advance cancer research. Read more about how NCI is strenghtening the cancer research enterprise.

  18. The Aldo Leopold Wilderness Research Institute: a national wilderness research program in support of wilderness management

    Science.gov (United States)

    Vita Wright

    2000-01-01

    The Aldo Leopold Wilderness Research Institute strives to provide scientific leadership in developing and applying the knowledge necessary to sustain wilderness ecosystems and values. Since its 1993 dedication, researchers at this federal, interagency Institute have collaborated with researchers and managers from other federal, academic and private institutions to...

  19. Institute of fundamental research: forty years of research

    International Nuclear Information System (INIS)

    1986-01-01

    This document is aimed at illustration of forty years of fundamental research at CEA. It has not been conceived to give an exhaustive view of current research at IRF, but to give an illustration of these researches to non-specialists, and even to non-scientifists [fr

  20. TTI Phase 2 Institutional Support: Ethiopian Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    For EDRI, this project will help enhance its research quality, organizational performance, and policy engagement. Performance and policy engagement. Through ... -strengthen the links between academics, policy communities, and institutions throughout Ethiopia and Eastern Africa -promote debate, encourage cooperation, ...

  1. Biotechnology and Nuclear Agriculture Research Institute (BNARI) at a glance

    International Nuclear Information System (INIS)

    2007-01-01

    Biotechnology and Nuclear Agriculture Research Institute (BNARI) was established in 1993 as one of the research, development and technology transfer institutes of the Ghana Atomic Energy Commission (GAEC). This was to help the GAEC to expand its research and development in the area of biotechnology and nuclear agriculture, which have been found to have a major impact on the agricultural development in countries involved in peaceful application of nuclear energy. The main objective of the Institute is to explore and exploit the application of isotopes, ionizing radiation and biotechnologies for increased agricultural and economic development of Ghana and to help the Country attain self-sufficiency in food and agriculture in order to alleviate malnutrition, hunger and poverty. This brochure describes the organizational structure; research facilities and programmes; services of the various departments of the Institute as well as achievements

  2. The OpenAIRE Guide for Research Institutions

    Directory of Open Access Journals (Sweden)

    Gültekin Gürdal

    2013-11-01

    Full Text Available This text is transcript of OpenAIRE Guide which is prepared in order to help research institutions was released on 13.04.2011and translated with the cooperation of ANKOS Open Access and Institutional Repositories Grup members and OpenAIREplus project team of Turkey which is coordinated from Izmir Institute of Technology Library. OpenAIRE Project aims to support researchers in complying with the European Commission Seventh Framework Programme Open Access Pilot through a European Helpdesk System; support researchers in depositing their research publications in an institutional or disciplinary repository; build up an OpenAIRE portal and e-infrastructure for repository networks. The project will work in tadem with OpeanAIREplus Project which has the principal goal of creating a robust, participatory service for the cross-linking of peer-reviewed scientific publications and associated datasets.

  3. U.S. Army Medical Research Institute of Infectious Diseases

    Science.gov (United States)

    ... in the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). The dedicated members of the USAMRIID staff ... military personnel and civilians from the threat of infectious diseases. We participate in support of emerging disease investigations, ...

  4. DESIGN OF THE RESEARCH INSTITUTION TYPE SITE MODEL

    Directory of Open Access Journals (Sweden)

    Natalia T. Zadorozhna

    2014-01-01

    Full Text Available The description of the model of site of research institution of NAPS of Ukraine (TSRI is presented. Goals and objectives оf the TSRI model are defined. Web 2.0 theoretical base for site development is considered, as well as described information environment, TSRI internet and intranet models. There are substantiated the site structure, design and site layout for research institution of NAPS of Ukraine. The example of the website of the Institute of Information Technologies and Learning Tools of the NAPS of Ukraine based on the TSRI model is showen. The technological aspects of the TSRI model are considered. There is given the scheme of internet-intranet environment to support scientific publications on pedagogical and psychological sciences. This paper is intended to web designers, researchers and administrative staff of research institutions.

  5. Institutional Support to South Asian Policy Research Organizations ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    There are very few policy research organizations in South Asia outside India. Those that exist are fragile due to little demand for policy research, limited if no funding from local sources, and an often insecure political climate. This grant will strengthen the ability of the seven selected research institutions in Bangladesh, Nepal ...

  6. Academic research at a South African higher education institution ...

    African Journals Online (AJOL)

    The aim of the research was to critically analyse how a university context influences the quality of academics' research output. Wenger's social theory of learning was used as theoretical framework. The investigation involved an ethnographic case study of the research culture at one college at the institution. Data collection ...

  7. TTI Phase 2 Institutional Support: Economic Policy Research Centre ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sound research, policy influence. TTI is a multi-funder program dedicated to strengthening independent policy research institutions, or think tanks, in developing countries. The program aims to enhance their ability to provide sound research that informs and influences policy. This second TTI phase (2014?2019) will fund 43 ...

  8. TTI Phase 2 Institutional Support: Centre for Policy Research | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    CPR is an independent, non-partisan research institute focused on improving policy-making and management, and promoting national development in India. CPR's research covers ... For CPR, this project will help enhance its research quality, organizational performance, and policy engagement. Policy influence in India

  9. TTI Phase 2 Institutional Support: Centre for Policy Research | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    CPR is an independent, non-partisan research institute focused on improving policy-making and management, and promoting national development in India. CPR's research covers ... For CPR, this project will help enhance its research quality, organizational performance, and policy engagement. Policy influence in India

  10. Institutional Support to Latin American Policy Research Organizations

    International Development Research Centre (IDRC) Digital Library (Canada)

    This grant will strengthen the ability of the 12 selected research institutions to provide, disseminate and communicate high-quality research. This will be achieved through measures aimed at enhancing the ability of staff to conduct sound research, improving organizational governance, and communicating with policymakers.

  11. The 30 Years Of National Institute Of Environmental Research

    International Nuclear Information System (INIS)

    2008-07-01

    This reports the history for 30 years of national institute of environment research from 1978 to 2008. It tells US the history, which includes the period of establishment of foundation, the period of expansion of the field on environment research and the period of leading of environment research for the 21st century, outcome of environment research on air, water, safe management of chemical substances and environment health and the future and vision of environment research.

  12. Research projects in the collaborative antwerp psychiatric research institute.

    Science.gov (United States)

    Sabbe, Bernard; Dom, Geert; Glazemakers, Inge; Goethals, Kris; Janssens, Astrid; Morrens, Manuel; Schrijvers, Didier; Van Den Eede, Filip; Van Hecke, Jan; Deboutte, Dirk; Van West, Dirk

    2010-11-01

    In the following article CAPRI presents its current research projects. The team leaders were asked to present and summarize the project they had been working on. The fields in which research was conducted are: Child and Adolescent Psychiatry, Cognitive and Psychomotor Dysfunctions in Schizophrenia, fMRI in Schizophrenia, Cognitive and Psychomotor Dysfunctions in Major Depressive Disorder, Chronic Fatigue Syndrome, Addiction Medicine and Forensic Psychiatry. An overview of recent and ongoing research projects is provided and the main results are summarized.

  13. Institute for Nuclear Research and Nuclear Energy and Nuclear Science

    International Nuclear Information System (INIS)

    Stamenov, J.

    2004-01-01

    The Institute for Nuclear Research and Nuclear Energy (INRNE) of the Bulgarian Academy of Sciences is the leading Bulgarian Institute for scientific investigations and applications of nuclear science. The main Institute's activities in the field of elementary particles and nuclear physics, high energy physics and nuclear energy, radiochemistry, radioecology, radioactive wastes treatment, monitoring of the environment, nuclear instruments development ect. are briefly described. Several examples for: environmental radiation monitoring; monitoring of the radioactivity and heavy metals in aerosols, 99m Tc clinical use, Boron Neutron Capture Therapy application of IRT-2000 Research Reactor, neutron fluence for reactor vessel embrittlement, NPP safety analysis, nuclear fuel modelling are also presented

  14. The Changing Landscape of Lung Cancer Research and Treatment

    Science.gov (United States)

    Along with the Lung Cancer Social Media (#LCSM) community, the National Cancer Institute will be co-hosting a lively and interactive Google Hangout on Air about the changing landscape of lung cancer research and treatment. During the chat, viewers will have the opportunity to pose questions to a panel of lung cancer experts including NCI's Dr. Shakun Malik, the head of thoracic oncology therapeutics, Roy S. Herbst, MD, PhD, Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven and David Tom Cooke MD FACS, Head, Section of General Thoracic Surgery University of California, Davis. You can also learn more and follow along on the #LCSM Chat page. The chat will be moderated by lung cancer advocate and #LCSM co-founder, Janet Freeman-Daily. To ask questions of our experts, simply use the #LCSM hashtag during the chat.

  15. Spatial analyses identify the geographic source of patients at a National Cancer Institute Comprehensive Cancer Center.

    Science.gov (United States)

    Su, Shu-Chih; Kanarek, Norma; Fox, Michael G; Guseynova, Alla; Crow, Shirley; Piantadosi, Steven

    2010-02-01

    We examined the geographic distribution of patients to better understand the service area of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, a designated National Cancer Institute (NCI) comprehensive cancer center located in an urban center. Like most NCI cancer centers, the Sidney Kimmel Comprehensive Cancer Center serves a population beyond city limits. Urban cancer centers are expected to serve their immediate neighborhoods and to address disparities in access to specialty care. Our purpose was to learn the extent and nature of the cancer center service area. Statistical clustering of patient residence in the continental United States was assessed for all patients and by gender, cancer site, and race using SaTScan. Primary clusters detected for all cases and demographically and tumor-defined subpopulations were centered at Baltimore City and consisted of adjacent counties in Delaware, Pennsylvania, Virginia, West Virginia, New Jersey and New York, and the District of Columbia. Primary clusters varied in size by race, gender, and cancer site. Spatial analysis can provide insights into the populations served by urban cancer centers, assess centers' performance relative to their communities, and aid in developing a cancer center business plan that recognizes strengths, regional utility, and referral patterns. Today, 62 NCI cancer centers serve a quarter of the U.S. population in their immediate communities. From the Baltimore experience, we might project that the population served by these centers is actually more extensive and varies by patient characteristics, cancer site, and probably cancer center services offered.

  16. Protocol Coordinator | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the consid erable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  17. Gastric cancer research in Mexico: a public health priority.

    Science.gov (United States)

    Sampieri, Clara Luz; Mora, Mauricio

    2014-04-28

    This study aimed review studies conducted on Mexican patients diagnosed with gastric cancer and/or diseases associated with its development, in which at least one Mexican institute has participated, and to assess their contributions to the primary and secondary prevention of this disease. A search of the Medline database was conducted using the following keywords: gastric/stomach cancer, Mexico. Studies of the Mexican population were selected in which at least one Mexican Institute had participated and where the findings could support public policy proposals directed towards the primary or secondary prevention of gastric cancer. Of the 148 studies found in the Medline database, 100 were discarded and 48 were reviewed. According to the analysis presented, these studies were classified as: epidemiology of gastric cancer (5/48); risk factors and protectors relating to gastric cancer (9/48); relationship between Helicobacter pylori and pathologies associated with gastric cancer and the development of the disease (16/48); relationship between the Epstein-Barr virus and pathologies associated with gastric cancer and the development of the disease (3/48); molecular markers for the development of diseases associated with gastric cancer and gastric cancer (15/48). Mexico requires a program for the prevention and control of gastric cancer based on national health indicators. This should be produced by a multidisciplinary committee of experts who can propose actions that are relevant in the current national context. The few studies of gastric cancer conducted on the Mexican population in national institutes highlight the poor connection that currently exists between the scientific community and the health sector in terms of resolving this health issue. Public policies for health research should support projects with findings that can be translated into benefits for the population. This review serves to identify national research groups studying gastric cancer in the Mexican

  18. Contract Funding Opportunities Available for Innovative SBIR Development | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    Does your small business need early-stage financing to take its cancer research to the next level? The National Cancer Institute Small Business Innovation Research (NCI SBIR) Development Center has released $5 million for new contract funding opportunities to support cancer research and technology development in key emerging areas of need. The NCI SBIR can help you finance and advance innovations in cancer prevention, diagnosis, treatment, and basic research.

  19. Booklet of the Research Institute of Clinical Medicine

    International Nuclear Information System (INIS)

    Todua, F.; Jgamadze, N.; Todua, N.; Beriashvili, Z.; Chelishvili, M.; Todua, I.; Chovelidze, Sh. et al.

    2012-01-01

    Research Institute of Clinical Medicine is one of the biggest university diagnostic and treatment centre in Georgia with unique modern diagnostic and treatment apparatus. The institute is acknowledged as a leader in various trends of radiology and surgery. The Research Institute of Clinical Medicine was founded in 1991. It is the leading scientific establishment in the field of medicine. The scientific-research work of the Institute is coordinated by the National Academy of Sciences of Georgia. The main scientific trend of the Institute is the Early Complex Diagnostics and Treatment. The scientific activity of the Institute is led by the Scientific Council. Institute achieved remarkable success since its foundation: It has been defended 56 theses for Candidate of Medical Sciences and 16 for Doctor of Medical Sciences; About 30 post-graduate students and more than 200 radiologists have taken training courses in radiology. Nowadays they work in different regions of Georgia, 21 inventions took out patents. It has been published 2000 scientific works and 9 monographs. (authors)

  20. [Training of institutional research networks as a strategy of improvement].

    Science.gov (United States)

    Galván-Plata, María Eugenia; Almeida-Gutiérrez, Eduardo; Salamanca-Gómez, Fabio Abdel

    2017-01-01

    The Instituto Mexicano del Seguro Social (IMSS) through the Coordinación de Investigación en Salud (Health Research Council) has promoted a strong link between the generation of scientific knowledge and the clinical care through the program Redes Institucionales de Investigación (Institutional Research Network Program), whose main aim is to promote and generate collaborative research between clinical, basic, epidemiologic, educational, economic and health services researchers, seeking direct benefits for patients, as well as to generate a positive impact on institutional processes. All of these research lines have focused on high-priority health issues in Mexico. The IMSS internal structure, as well as the sufficient health services coverage, allows the integration of researchers at the three levels of health care into these networks. A few years after their creation, these networks have already generated significant results, and these are currently applied in the institutional regulations in diseases that represent a high burden to health care. Two examples are the National Health Care Program for Patients with Acute Myocardial Infarction "Código Infarto", and the Early Detection Program on Chronic Kidney Disease; another result is the generation of multiple scientific publications, and the promotion of training of human resources in research from the same members of our Research Networks. There is no doubt that the Coordinación de Investigación en Salud advances steadily implementing the translational research, which will keep being fruitful to the benefit of our patients, and of our own institution.

  1. Patient Care Coordinator | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  2. Challenges in Education Research in Taiwan: Research Institutes and Organizations, Research Policies, and Problems

    Directory of Open Access Journals (Sweden)

    Jia Li Huang

    2017-02-01

    Full Text Available Since the 1990s, many education researchers and policy makers worldwide have reviewed education research to attempt to provide strategies to improve the quality of such research in their countries. Taiwan’s government has launched policies and funded support to set the benchmark for Taiwan’s leading universities in international academic competition. The external environment of global competition based on research policy influences the ecosystem of social science research production. To assure the quality of education policy, peer review from within the education community is one approach to supplementing the government’s governance, including the establishment of research institutes, promotion, rewards, and research value. This study tracked the mode of academic research and provides an overview of the status of academic education research in Taiwan. Because education research is part of the humanities and social sciences fields, this study identified the challenges in educational research by examining the trend of social science research and by analyzing research organizations, policy, and the evaluation of research performance. Due to the environment of education research in Taiwan is not friendly to education researcher to accumulate papers in SSCI or international journal, additional concerns entail how education research communities can develop and agree on its quality.

  3. Japan Atomic Energy Research Institute in the 21st century

    International Nuclear Information System (INIS)

    Sato, Y.

    2001-01-01

    Major nuclear research institutes in Japan are the Japan Atomic Energy Research Institute (JAERI), Nuclear Cycle Development Institute (JNC), National Research Institute of Radiological Science (NIRS), and the Institute of Physical and Chemical Research (RIKEN). In the 50s and 60s JAERI concentrated on the introduction of nuclear technology from overseas. Energy security issues led to the development of a strong nuclear power programme in the next two decades resulting in Japan having 50 light water cooled nuclear power plants in operation. Japan also worked on other reactor concepts. The current emphasis of JAERI is on advanced reactors and nuclear fusion. Its budget of 270 million US$ supports five research establishments. JAERI has strong collaboration with industry and university system on nuclear and other advanced research topics (neutron science, photon science). In many areas Japan has strong international links. JAERI has also been transferring know-how on radioisotope and radiation applications to the developing countries particularly through IAEA-RCA mechanisms. (author)

  4. Prospective multi-institutional study evaluating the performance of prostate cancer risk calculators.

    Science.gov (United States)

    Nam, Robert K; Kattan, Michael W; Chin, Joseph L; Trachtenberg, John; Singal, Rajiv; Rendon, Ricardo; Klotz, Laurence H; Sugar, Linda; Sherman, Christopher; Izawa, Jonathan; Bell, David; Stanimirovic, Aleksandra; Venkateswaran, Vasundara; Diamandis, Eleftherios P; Yu, Changhong; Loblaw, D Andrew; Narod, Steven A

    2011-08-01

    Prostate cancer risk calculators incorporate many factors to evaluate an individual's risk for prostate cancer. We validated two common North American-based, prostate cancer risk calculators. We conducted a prospective, multi-institutional study of 2,130 patients who underwent a prostate biopsy for prostate cancer detection from five centers. We evaluated the performance of the Sunnybrook nomogram-based prostate cancer risk calculator (SRC) and the Prostate Cancer Prevention Trial (PCPT) -based risk calculator (PRC) to predict the presence of any cancer and high-grade cancer. We examined discrimination, calibration, and decision curve analysis techniques to evaluate the prediction models. Of the 2,130 patients, 867 men (40.7%) were found to have cancer, and 1,263 (59.3%) did not have cancer. Of the patients with cancer, 403 (46.5%) had a Gleason score of 7 or more. The area under the [concentration-time] curve (AUC) for the SRC was 0.67 (95% CI, 0.65 to 0.69); the AUC for the PRC was 0.61 (95% CI, 0.59 to 0.64). The AUC was higher for predicting aggressive disease from the SRC (0.72; 95% CI, 0.70 to 0.75) compared with that from the PRC (0.67; 95% CI, 0.64 to 0.70). Decision curve analyses showed that the SRC performed better than the PRC for risk thresholds of more than 30% for any cancer and more than 15% for aggressive cancer. The SRC performed better than the PRC, but neither one added clinical benefit for risk thresholds of less than 30%. Further research is needed to improve the AUCs of the risk calculators, particularly for higher-grade cancer.

  5. Forschungszentrum Rossendorf, Institute of Safety Research. Annual report 2004

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, F.P.; Rindelhardt, U. (eds.)

    2005-07-01

    The Institute of Safety Research (ISR) is one of the six Research Institutes of Forschungszentrum Rossendorf e.V. (FZR e.V.) which is a member institution of the Wissenschaftsgemeinschaft Gottfried Wilhelm Leibniz (Leibniz Association). Together with the Institute of Radiochemistry, ISR constitutes the research programme ''Safety and Environment'' which is one from three scientific programmes of FZR. In the framework of this research programme, the institute is responsible for the two subprogrammes ''Plant and Reactor Safety'' and ''Thermal Fluid Dynamics'', respectively. We also provide minor contributions to the sub-programme ''Radio-Ecology''. Moreover, with the development of a pulsed photo-neutron source at the radiation source ELBE (Electron linear accelerator for beams of high brilliance and low emittance), we are involved in a networking project carried out by the FZR Institute of Nuclear and Hadron Physics, the Physics Department of TU Dresden, and ISR. (orig.)

  6. Energy-Efficiency & Water Institute Research Facility, Purdue University, (IN)

    Energy Technology Data Exchange (ETDEWEB)

    Nnanna, Agbai [Purdue Univ., West Lafayette, IN (United States)

    2015-01-30

    The renovation of the Schneider Avenue Building to construct two research laboratories within the building is complete. The research laboratories are for the Purdue Calumet Water Institute and the Energy Efficiency and Reliability Center. The Water Institute occupies approximately 1000+ SF of research space plus supporting offices. The Energy-Efficiency Center occupies approximately 1000+ SF that houses the research space. The labs will enhance the Water & Energy Institute’s research capabilities necessary to tackle these issues through the development of practical approaches critical to local government and industry. The addition of these research laboratories to the Purdue University Calumet campus is in both direct support of the University’s Strategic Plan as well as the 2008 Campus Master Plan that identifies a 20% shortage of research space.

  7. 279 Department of Agronomy/Sugar Research Institute, University of ...

    African Journals Online (AJOL)

    Osondu

    2014-04-09

    Apr 9, 2014 ... sugarcane crop is affected by 20-25 percent (%) due to weed infestation (Khan et al., 2004). Weed management therefore in sugarcane accounts for over 35% ..... Indian. Journal of Weed Science 34(3-4): 320-321. USRI (2009). Unilorin Sugar Research Institute: Report of Research activities (2005-2009).

  8. Institutional Support : Consortium for Economic and Social Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Institutional Support : Consortium for Economic and Social Research (CRES) Sénégal. The Consortium pour la recherche économique et sociale (CRES) is an association of a multidisciplinary team of researchers based in Dakar, Sénégal. Its activities are organized under five departments: growth, poverty and equity; local ...

  9. Institutional Support to Policy Research Organizations in India ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC's Think Tank Initiative is a multi-donor program dedicated to strengthening independent policy research institutions, or "think tanks," in developing countries, thereby enabling them to produce sound research that both informs and influences policy. The Initiative selected the first cohort of 24 grantees in East and West ...

  10. TTI Phase 2 Institutional Support: Ethiopian Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    -promote debate, encourage cooperation, and improve the communication of ideas -attract and retain staff -improve organizational, financial management, and audit systems -expand its outreach opportunities to effectively communicate and report research findings -become Ethiopia's leading research institute in the field of ...

  11. Institutional Support to South Asian Policy Research Organizations ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC's Think Tank Initiative is a multi-donor program dedicated to strengthening independent policy research institutions (think tanks) in developing countries, thereby enabling them to produce sound research that both informs and influences policy. The Initiative selected the first cohort of 24 grantees in East and West ...

  12. Key Institutions in Business and Management Education Research

    Science.gov (United States)

    Fornaciari, Charles J.; Arbaugh, J. B.; Asarta, Carlos J.; Bento, Regina F.; Hwang, Alvin; Lund Dean, Kathy

    2017-01-01

    The authors investigate institutional productivity in business and management education (BME) research based on the analysis of 4,464 articles published by 7,210 authors across 17 BME journals over a 10-year period, involving approximately 1,900 schools worldwide. Departing from traditional disciplinary silos, they examine the BME research field…

  13. The assessment of research support in a distance learning institution

    African Journals Online (AJOL)

    With technikons becoming universities of technologies, the emphasis is now on their ability to effectively offer research degrees, e.g. master's degrees and doctorates. Some of these institutions are not well developed in terms of research supervision. It is even more difficult, but also very necessary, for a distance education ...

  14. Institutional Research in Australasia: Coming of Age or Coming Unstuck?

    Science.gov (United States)

    Hanlon, Martin; Rothery, Michael; Daldy, Rob

    2011-01-01

    The scope of institutional research (IR) undertaken in Australasian universities is progressively expanding. A traditional focus on student life cycle elements such as enrolment, retention and satisfaction has been complemented for some years now by other areas of focus including research performance and community engagement. More recently,…

  15. 1991 annual report of the Karlsruhe Federal Food Research Institute

    International Nuclear Information System (INIS)

    1992-01-01

    The Federal Food Research Institute does research in the field of nutrition, food and household sciences as well as in related special fields. Among its working priorities are the determination of foreign matter and radionuclides in food as well as food preservation by means of irradiation including dosimetry. The results of those priorities are represented. (orig./MG) [de

  16. A Ten Year Citation Analysis of Major Australian Research Institutions

    Science.gov (United States)

    Batterham, Robin J.

    2011-01-01

    The introduction of the Excellence in Research for Australia scheme has heightened debate amongst research institutions over the use of metrics such as citations, especially given the ready availability of citation data. An analysis is presented of the citation performance of nine Australian universities and the Commonwealth Scientific, Industrial…

  17. Main directions of Research Institute of Experimental and Theoretic Physics

    International Nuclear Information System (INIS)

    Tazhibaeva, I.L.

    1997-01-01

    The characteristic of main directions of the Research Institute of Experimental and Theoretic Physics (RIETF) activity is given in the paper. It is noted, that Institute is headquarters organisation in 4 following scientific programs of Ministry of Science - Academy of Science of Republic of Kazakhstan: Physics and mechanics of gases, plasma and liquid; Theoretical physics; Nonlinear processes and structural self-organization of substance; Research works Comet. Since 1994 RIETF is one of executors on interstate scientific program ITER. There are following priorities in activity of the institute: - actual problems of relativity theory, gravitation and quantum mechanics; - research on combustion problems and heat-mass-transfer; - physics of gases, plasma and liquid; physics non-equilibrium processes in plasma an in plasma-similar media; - solid state physics and material testing problems; modification of materials properties; electrophysical, optical and structural researches of substance; - interactions of nuclear, electromagnet radiation and accelerated particles with substance; - theoretical and experimental nuclear physics and physics of cosmic rays

  18. Possible new treatment for Kaposi sarcoma | Center for Cancer Research

    Science.gov (United States)

    A collaborative effort by researchers at the National Cancer Institute (NCI) and Celgene Corporation, a global biopharmaceutical company, has yielded a possible new treatment for Kaposi sarcoma (KS), a cancer caused by a human gammaherpesvirus. The drug, called pomalidomide, is highly effective against KS and has fewer side effects compared with chemotherapy, suggesting that it may be a useful alternative to traditional therapies. Read more...

  19. Challenges facing the marketing of scientific and research institutes

    Directory of Open Access Journals (Sweden)

    Bogdan Sojkin

    2015-12-01

    Full Text Available This article presents the challenges that scientific research institutions face in terms of their marketing, which have been divided into two groups of those associated with internal marketing and those linked to external marketing. The most significant and important determinants that constitute challenges to both internal and external marketing were described. The key aspects of each of the identified challenges were indicated, as was their impact on the implementation of the marketing policy at institutions.

  20. Central Institute of Nuclear Research Rossendorf 25 years old

    International Nuclear Information System (INIS)

    Hohmuth, K.; Kaun, K.H.; Schmidt, A.; Hennig, K.; Brinckmann, H.F.; Lehmann, E.; Rossbander, W.; Bitterlich, H.; Weibrecht, R.; Fuelle, R.; Nebel, D.; Reetz, T.; Beyer, G.J.; Muenze, R.

    1981-12-01

    A colloquium dedicated the 25th anniversary of the foundation of the Central Institute for Nuclear Research of the GDR Academy of Sciences was held on January, 21st, '81. 13 papers were given which dealt with aspects of the institute's history as well as with modern trends in nuclear and solid state physics, nuclear energy and chemistry, radioisotope production, radiation protection and nuclear information. (author)

  1. Customer Relationship Management in scientific and research institutions

    Directory of Open Access Journals (Sweden)

    Jaromir Matulewicz

    2013-12-01

    Full Text Available Basing on the example of a scientific institute, this article shows: – potential areas in which CRM philosophy, procedures and tools could be applied – purpose of applying CRM – outcomes to expect from CRM application The article shows the Customer Relationship Management idea exclusively, along with areas of its use in scientific and research institutions and also a proposal to determine a group of clients for these institutions. The summary of the article consists of information regarding sources of knowledge about CRM philosophy and procedures (mainly bibliographical and also about IT systems which support CRM.

  2. Academic Libraries’ Role in Improving Institutions Research Impact

    KAUST Repository

    Tamarkin, Molly

    2015-11-11

    In the changing landscape of scientific research and scholarly communication, importance of “quality in research”, “reviewed research” and “reviewed publications” in qualifying for the ratings and rankings are widely discussed. While publishing the research pieces in peer-reviewed and highly ranked journals are increasingly important, there are different methods and tools to be in place at Institutional level to increase researchers’ profile and the ranking of the institutions. As a young research based university created in 2009, King Abdullah University of Science and Technology (KAUST) focuses on the bibliometrics and altemetrics tools, author affiliations, author naming and plug-ins to different search engines, research evaluation systems as well as to research repositories. The University has launched an institutional repository in September 2012 as a home for the intellectual outputs of KAUST researchers, and then adopted the first institutional open access mandate in the Arab region effective June 31, 2014. Integration with ORCID became a key element in this process and the best way to ensure data quality for researcher’s scientific contributions systematically. We will present the inclusion and creation of ORCID identifiers in the existing systems as an institutional member to ORCID, and the creation of dedicated integration tools with Current Research Information System (CRIS) as a standardized common resource to monitor KAUST research outputs. We will also present our experiences in awareness programs, trainings, outreach, implementation of systems and tools like PlumX, as well as our approach in improving the research impact and profiling our Institution’s research to the world.

  3. An Analysis of Canadian Institute for Health Research Funding for Research on Autism Spectrum Disorder

    Directory of Open Access Journals (Sweden)

    R. Deonandan

    2016-01-01

    Full Text Available We examined patterns of Canadian Institute for Health Research (CIHR funding on autism spectrum disorder (ASD research. From 1999 to 2013, CIHR funded 190 ASD grants worth $48 million. Biomedical research received 43% of grants (46% of dollars, clinical research 27% (41%, health services 10% (7%, and population health research 8% (3%. The greatest number of grants was given in 2009, but 2003 saw the greatest amount. Funding is clustered in a handful of provinces and institutions, favouring biomedical research and disfavouring behavioural interventions, adaptation, and institutional response. Preference for biomedical research may be due to the detriment of clinical research.

  4. Dr. Ted Trimble: Why I Do Cancer Research

    Science.gov (United States)

    In a video, Dr. Ted Trimble talks about the importance of cancer research. World Cancer Research Day commemorates the important role research and cancer researchers play in reducing the global burden of cancer.

  5. Evaluation acting: the experience of a public research institute

    International Nuclear Information System (INIS)

    Guimaraes, Regia Ruth Ramirez; Ferreira, Hudson Rubio; Filgueiras, Sergio A. Cunha

    2007-01-01

    Innovation and knowledge management are central questions of the modern world economy where the incorporation of new knowledge is determining for competition. In this context, there is a movement of pression under public research institutions for a more dynamic participation on the local innovation system. The institutions of C and T should prepare to help the companies to insert in the context of open economies and also to compete in the global market. The modernity requires flexibility and organizational changes in the research institutions. Redefinitions of their practices in relation to other aspects such as: financing sources; partnership with other organizations; definition and planning of the objectives; evaluation, diffusion and valorization of the results and the establishing of a measuring system and performance indicators. Aiming at having an effective institutional insertion on the national and regional systems of innovation, the Nuclear Technology Development Center - CDTN reformulated its strategical planning, incorporating the view of the researchers of the Center and external experts. As part of the evaluation process, CDTN organizes an annual seminar for evaluating its projects, focused on presenting the results and also on the analysis of the performance indicators. The result of this pairs review are widely informed to the Institution and is an important tool for the critical analysis of the institutional performance and for corrections to be made by the high direction. This paper presents the methodology for evaluating the results, as well as the difficulties and improvements incorporated to the process, which has been applied for three years. (author)

  6. Programmer Analyst | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Advanced Biomedical Computing Center (ABCC) provides technology development, scientific consultation, collaboration, data analysis and training to the National Cancer Institute (NCI) and National Institutes of Health (NIH) scientists and staff. The Core Infrastructure and Systems Biology (CISB) group in ABCC strives to streamline and provide innovative solutions for the NCI/NIH community to access and use biological information collected across different sources and formats. Integrating diverse data sources to enable disease agnostic access and analysis, variant impact annotation, identifier conversions across species, and merging clinical and research data enables translation from basic to the goal of precision medicine. CISB is looking for an experienced analyst to support the database and application management efforts at the NCI’s Molecular Targets Program (MTP). KEY ROLES/RESPONSIBILITIES Provide data management and analysis support Maintain scientific applications and databases on single-user personal computer through the multi-user, multi-processor large memory mainframe Communicate with the experts in the MTP, gather requirements and provide support Provide training to researchers on a variety of platforms and applications Evaluate and develop methodologies to allow utilization of new software tools and generate the information required by MTP researchers Determine methods and procedures on new assignments Document approaches and mechanisms clearly and comprehensively

  7. Developmental Scientist | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and

  8. Challenges in cancer research and multifaceted approaches for cancer biomarker quest

    Czech Academy of Sciences Publication Activity Database

    Martinková, Jiřina; Gadher, S. J.; Hajduch, M.; Kovářová, Hana

    2009-01-01

    Roč. 583, - (2009), s. 1772-1784 ISSN 0014-5793 R&D Projects: GA MŠk LC07017 Institutional research plan: CEZ:AV0Z50450515 Keywords : cancer research * proteomics * genomics Subject RIV: FD - Oncology ; Hematology Impact factor: 3.541, year: 2009

  9. Forschungszentrum Rossendorf. Institute of Safety Research. Annual report 1998

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, F.P.; Rindelhardt, U. [eds.

    1999-07-01

    The Institute of Safety Research is one of the five scientific institutes of Forschungszentrum Rossendorf e.V. The Forschungszentrum Rossendorf is a member of the 'Wissenschaftsgemeinschaft Gottfried Wilhelm Leibniz' und is funded by the Federal Ministry of Education and Research and by the Saxon Ministry of Science and Arts with 50% each. The research work of the institute aims at the assessment and increase of the safety and environmental sustainability of technical plants. The emphasis is put on the development and validation of mathematical and physical models for process and plant analysis, and of techniques for process and components monitoring. Subject of investigations are equally nuclear plants and installations of process industries. (orig.)

  10. Forschungszentrum Rossendorf. Institute of Safety Research. Annual report 1998

    International Nuclear Information System (INIS)

    Weiss, F.P.; Rindelhardt, U.

    1999-07-01

    The Institute of Safety Research is one of the five scientific institutes of Forschungszentrum Rossendorf e.V. The Forschungszentrum Rossendorf is a member of the 'Wissenschaftsgemeinschaft Gottfried Wilhelm Leibniz' und is funded by the Federal Ministry of Education and Research and by the Saxon Ministry of Science and Arts with 50% each. The research work of the institute aims at the assessment and increase of the safety and environmental sustainability of technical plants. The emphasis is put on the development and validation of mathematical and physical models for process and plant analysis, and of techniques for process and components monitoring. Subject of investigations are equally nuclear plants and installations of process industries. (orig.)

  11. 1994 - 1995 annual report of the NRC Biotechnology Research Institute

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    One of the roles of the Biotechnology Research Institute is to promote leading edge research and development in biotechnology and molecular biology as they relate to industries in the natural resource sectors. To this end, researchers work with industry to develop less polluting, more efficient and economic processes and to solve environmental problems. Scientific studies undertaken in 1994 and 1995 included new analytical techniques and biosensors, bioprocesses for waste and ground water treatment, biopesticides, biodegradation of toxic compounds, biodesulfurization of bitumen, solvent- less sample preparation techniques to analyze environmental pollutants in soils and waste water, protocol for the analysis of petroleum hydrocarbons, gene probes and their applications, biodegradation of energetic compounds, and biofiltration of air emissions. These, and other noteworthy projects undertaken by the Institute, were reviewed and presented ,combined with institutional data. 2 tabs.

  12. Research in Danish cancer rehabilitation

    DEFF Research Database (Denmark)

    Høybye, Mette Terp; Dalton, Susanne Oksbjerg; Christensen, Jane

    2008-01-01

    Worldwide, the number of cancer survivors is increasing, owing to improvements in cancer therapy, resulting in an increased need to address the physical and mental sequelae of cancer. This paper introduces a Danish psychosocial cancer intervention and presents the baseline characteristics...

  13. Radiation protection code of practice in academic and research institutes

    International Nuclear Information System (INIS)

    Abdalla, A. A. M.

    2010-05-01

    The main aim of this study was to establish a code of practice on radiation protection for safe control of radiation sources used in academic and research institutes, another aim of this study was to assess the current situation of radiation protection in some of the academic and research institutes.To achieve the aims of this study, a draft of a code of practice has been developed which is based on international and local relevant recommendation. The developed code includes the following main issues: regulatory responsibilities, radiation protection program and design of radiation installations. The second aim had been accomplished by conducting inspection visits to five (A, B, C, D and E) academic and to four (F, G, H and I ) research institutes. Eight of such institutes are located in Khartoum State and the ninth one is in Madani city (Aljazeera State). The inspection activities have been carried out using a standard inspection check list developed by the regulatory authority of the Sudan. The inspection missions to the above mentioned institutes involved also evaluation of radiation levels around the premises and storage areas of radiation sources. The dose rate measurement around radiation sources locations were found to be quite low. This mainly is due to the fact that the activities of most radionuclides that are used in these institutes are quite low ( in the range of micro curies). Also ,most the x-ray machines that were found in use for scientific academic and research purposes work at low k Vp of maximum 60 k Vp. None of the radiation workers in the inspected institutes has a personal radiation monitoring device, therefor staff dose levels have not been assessed. However it was noted that in most of the academic/ research studies radiation workers are only exposed to very low levels of radiation and for a very short time that dose not exceed 1 minute, therefore the expected occupational exposure of the staff is very low. Radiation measurement in public

  14. A Comprehensive Infrastructure for Big Data in Cancer Research: Accelerating Cancer Research and Precision Medicine

    Directory of Open Access Journals (Sweden)

    Izumi V. Hinkson

    2017-09-01

    Full Text Available Advancements in next-generation sequencing and other -omics technologies are accelerating the detailed molecular characterization of individual patient tumors, and driving the evolution of precision medicine. Cancer is no longer considered a single disease, but rather, a diverse array of diseases wherein each patient has a unique collection of germline variants and somatic mutations. Molecular profiling of patient-derived samples has led to a data explosion that could help us understand the contributions of environment and germline to risk, therapeutic response, and outcome. To maximize the value of these data, an interdisciplinary approach is paramount. The National Cancer Institute (NCI has initiated multiple projects to characterize tumor samples using multi-omic approaches. These projects harness the expertise of clinicians, biologists, computer scientists, and software engineers to investigate cancer biology and therapeutic response in multidisciplinary teams. Petabytes of cancer genomic, transcriptomic, epigenomic, proteomic, and imaging data have been generated by these projects. To address the data analysis challenges associated with these large datasets, the NCI has sponsored the development of the Genomic Data Commons (GDC and three Cloud Resources. The GDC ensures data and metadata quality, ingests and harmonizes genomic data, and securely redistributes the data. During its pilot phase, the Cloud Resources tested multiple cloud-based approaches for enhancing data access, collaboration, computational scalability, resource democratization, and reproducibility. These NCI-led efforts are continuously being refined to better support open data practices and precision oncology, and to serve as building blocks of the NCI Cancer Research Data Commons.

  15. The law for the Japan Atomic Energy Research Institute

    International Nuclear Information System (INIS)

    1977-01-01

    The law establishes the Japan Atomic Energy Research Institute in accordance with the Basic Act on Atomic Energy as a government corporation for the purpose of promoting R and D and utilizations of atomic energy (first chapter). The second chapter concerns the directors, advisers and personnel of the institute, namely a chairman of the board of directors, a vice-chairman, directors not more than seven persons, and auditors not more than two persons. The chairman represents and supervises the intitute, whom the prime minister appoints with the agreement of Atomic Energy Commission. The vice-chairman and other directors are nominated by the chairman with the approval of the prime minister, while the auditors are appointed by the prime minister with the advice of the Atomic Energy Commission. Their terms of office are 4 years for directors and 2 years for auditors. The third chapter defines the scope of activities of the institute as follows: basic and applied researches on atomic energy; design, construction and operation of nuclear reactors; training of researchers and technicians; and import, production and distribution of radioisotopes. Those activities should be done in accordance with the basic development and utilization plans of atomic energy established by the prime minister with the determination of Atomic Energy Commission. The fourth chapter provides for the finance and accounting of the institute, and the fifth chapter requires the supervision of the institute by the prime minister. (Matsushima, A.)

  16. The law for the Japan Atomic Energy Research Institute

    International Nuclear Information System (INIS)

    1979-01-01

    The institute is established under the atomic energy basic law to make effectively research of development of atomic energy in general and help to promote investigation, development and utilization of it. The institute is a legal person and has its main office in Tokyo. Its capital is the amount of yen 2,500 million plus contributions by persons other than the government. The government invests the said yen 2,500 million at the time of its establishment. The articles of the institute shall prescribe matters, such as: capital, contributions and assets; officer and meeting; business and its execution; accounting, etc. The officers are consisted of a chief director, a deputy chief director and less than 7 directors and less than 2 auditors. The chief director is appointed by the Prime Minister with the consent of the atomic energy commission. The term of the chief director, the deputy chief director and directors is 4 years and that of auditors is 2 years. Functions of the institute include basic and application research of atomic energy, planning, building and operation of reactors, training of researchers and engineers of atomic energy, etc. The budget, the business program and the financial project shall be prepared each business year and authorized by the Prime Minister. The institute is subject to the supervision of the Prime Minister. (Okada, K.)

  17. Mobilisation for public engagement: Benchmarking the practices of research institutes.

    Science.gov (United States)

    Entradas, Marta; Bauer, Martin M

    2017-10-01

    Studies on scientists' practices of public engagement have pointed to variations between disciplines. If variations at the individual level are reflected at the institutional level, then research institutes in Social Sciences (and Humanities) should perform higher in public engagement and be more involved in dialogue with the public. Using a nearly complete sample of research institutes in Portugal 2014 ( n = 234, 61% response rate), we investigate how public engagement varies in intensity, type of activities and target audiences across scientific areas. Three benchmark findings emerge. First, the Social Sciences and the Humanities profile differently in public engagement highlighting the importance of distinguishing between these two scientific areas often conflated in public engagement studies. Second, the Social Sciences overall perform more public engagement activities, but the Natural Sciences mobilise more effort for public engagement. Third, while the Social Sciences play a greater role in civic public engagement, the Natural Sciences are more likely to perform educational activities. Finally, this study shows that the overall size of research institutes, available public engagement funding and public engagement staffing make a difference in institutes' public engagement.

  18. [Recommendations for cancer prevention of World Cancer Research Fund (WCRF): situational analysis for Chile].

    Science.gov (United States)

    Crovetto, Mirta; Uauy, Ricardo

    2013-05-01

    The main diet-related cancers include colorectal, lung, breast in (postmenopausal) women, stomach, esophagus, prostate and pancreas. After tobacco, obesity is the leading cause of cancer; it accounts for one third of all cancers. Cancer is associated with high total body fat, abdominal fat and weight gain in adult life. These are all potentially modifiable risk factors. Consumption of a "healthy diet" and living an "active life" can significantly reduce the risk of cancer. The aim of this study was to analyze the recommendations published by the World Cancer Research Fund (WCRF) and American Institute for Cancer Research (AICR) for the prevention of cancer in 2007. We compared the recommendations of Food, Nutrition and Physical Activity and the Prevention of Cancer: a global perspective", with the national situation in Chile, analyzing the national report on the prevalence of risk factors. Our main finding was that the pattern of consumption and lifestyles differ markedly from the WCRF recommendations: we observed an over consumption of sugary drinks and high intake of processed foods high in sodium and total fat and low consumption of legumes, vegetables, fruits high in antioxidants and fiber that protect from cancer. Chile has an increased cancer prevalence which is associated with poor quality diets, rising mean body mass index and a sedentary behavior. We recommend the strengthening programs to promote healthy diets and active living, in order to reduce cancer risk.

  19. The ISB Cancer Genomics Cloud: A Flexible Cloud-Based Platform for Cancer Genomics Research.

    Science.gov (United States)

    Reynolds, Sheila M; Miller, Michael; Lee, Phyliss; Leinonen, Kalle; Paquette, Suzanne M; Rodebaugh, Zack; Hahn, Abigail; Gibbs, David L; Slagel, Joseph; Longabaugh, William J; Dhankani, Varsha; Reyes, Madelyn; Pihl, Todd; Backus, Mark; Bookman, Matthew; Deflaux, Nicole; Bingham, Jonathan; Pot, David; Shmulevich, Ilya

    2017-11-01

    The ISB Cancer Genomics Cloud (ISB-CGC) is one of three pilot projects funded by the National Cancer Institute to explore new approaches to computing on large cancer datasets in a cloud environment. With a focus on Data as a Service, the ISB-CGC offers multiple avenues for accessing and analyzing The Cancer Genome Atlas, TARGET, and other important references such as GENCODE and COSMIC using the Google Cloud Platform. The open approach allows researchers to choose approaches best suited to the task at hand: from analyzing terabytes of data using complex workflows to developing new analysis methods in common languages such as Python, R, and SQL; to using an interactive web application to create synthetic patient cohorts and to explore the wealth of available genomic data. Links to resources and documentation can be found at www.isb-cgc.org Cancer Res; 77(21); e7-10. ©2017 AACR . ©2017 American Association for Cancer Research.

  20. Decontamination and decommissioning in the Nuclear Research Institute Rez plc

    Energy Technology Data Exchange (ETDEWEB)

    Kovarik, P.; Podlaha, J. [Nuclear Research Institute Rez plc, Rez (Czech Republic)

    2007-04-15

    The Nuclear Research Institute Rez (NRI) is a leading institution in the area of Decontamination and Decommissioning in the Czech Republic. The NRI has maintained a dominant position in the nuclear program of the former Czechoslovakia since it was established in 1955 as a state-owned research organization. In December 1992 the NRI has been transformed into a joint-stock company. The Institute's activity encompasses nuclear physics, radiochemistry, experiments at the research reactor and many other topics. At present, research activities are mainly targeted at assisting the nuclear safety regulating body, power plant operator and nuclear facilities contractors. Significant attention is also paid to the use of nuclear technology outside the nuclear power sector. NRI operates 2 research nuclear reactors, hot cell facility, research laboratories, technology for radioactive waste management, radionuclide constructions for irradiation, and others. After 50 years of activities in the nuclear field, there are many environmental liabilities that shall be remedied. Such remedies are broken down to three areas: 1. Decommissioning of old obsolete facilities (e.g. decay tanks, liquid RAW storage tanks, old RAW treatment technology, special sewage system), 2. Processing of RAW resulting from operation and dismantling of nuclear facilities and 3. Elimination of spent fuel from research nuclear reactors. The goal is to remedy the environmental liabilities and eliminate the potential negative impact on the environment. Remediation of the environmental liabilities started in 2003 and should be finished in 2012. (orig.)

  1. Rehabilitation Research at the National Institutes of Health:

    Science.gov (United States)

    Bean, Jonathan F.; Damiano, Diane; Ehrlich-Jones, Linda; Fried-Oken, Melanie; Jette, Alan; Jung, Ranu; Lieber, Rick L.; Malec, James F.; Mueller, Michael J.; Ottenbacher, Kenneth J.; Tansey, Keith E.; Thompson, Aiko

    2017-01-01

    Abstract Approximately 53 million Americans live with a disability. For decades, the National Institutes of Health (NIH) has been conducting and supporting research to discover new ways to minimize disability and enhance the quality of life of people with disabilities. After the passage of the American With Disabilities Act, the NIH established the National Center for Medical Rehabilitation Research with the goal of developing and implementing a rehabilitation research agenda. Currently, a total of 17 institutes and centers at NIH invest more than $500 million per year in rehabilitation research. Recently, the director of NIH, Dr Francis Collins, appointed a Blue Ribbon Panel to evaluate the status of rehabilitation research across institutes and centers. As a follow-up to the work of that panel, NIH recently organized a conference under the title “Rehabilitation Research at NIH: Moving the Field Forward.” This report is a summary of the discussions and proposals that will help guide rehabilitation research at NIH in the near future. This article is being published almost simultaneously in the following six journals: American Journal of Occupational Therapy, American Journal of Physical Medicine and Rehabilitation, Archives of Physical Medicine and Rehabilitation, Neurorehabilitation and Neural Repair, Physical Therapy, and Rehabilitation Psychology. Citation information is as follows: Frontera WR, Bean JF, Damiano D, et al. Am J Phys Med Rehabil. 2017;97(4):393–403. PMID:28499004

  2. A comparison of cancer burden and research spending reveals discrepancies in the distribution of research funding

    Directory of Open Access Journals (Sweden)

    Carter Ashley JR

    2012-07-01

    Full Text Available Abstract Background Ideally, the distribution of research funding for different types of cancer should be equitable with respect to the societal burden each type of cancer imposes. These burdens can be estimated in a variety of ways; “Years of Life Lost” (YLL measures the severity of death in regard to the age it occurs, "Disability-Adjusted Life-Years" (DALY estimates the effects of non-lethal disabilities incurred by disease and economic metrics focus on the losses to tax revenue, productivity or direct medical expenses. We compared research funding from the National Cancer Institute (NCI to a variety of burden metrics for the most common types of cancer to identify mismatches between spending and societal burden. Methods Research funding levels were obtained from the NCI website and information for societal health and economic burdens were collected from government databases and published reports. We calculated the funding levels per unit burden for a wide range of different cancers and burden metrics and compared these values to identify discrepancies. Results Our analysis reveals a considerable mismatch between funding levels and burden. Some cancers are funded at levels far higher than their relative burden suggests (breast cancer, prostate cancer, and leukemia while other cancers appear underfunded (bladder, esophageal, liver, oral, pancreatic, stomach, and uterine cancers. Conclusions These discrepancies indicate that an improved method of health care research funding allocation should be investigated to better match funding levels to societal burden.

  3. Basic research on cancer related to radiation associated medical researches

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong In; Hwang, Dae Yong; Bang, Ho Yoon [and others

    2000-12-01

    Basic Research on Cancer related to Radiation Associated Medical Researches including 1. Establishment of animal model of colorectal cancer liver metastasis and measurement of angiogenesis, 2. Tissue expression of Tie-1 and Tie-2 in human colorectal cancer, 3. Enhancement of G2/Mphase Cell Fraction by Adenovirus-mediated p53 Gene Transfer in Ovarian Cancer Cell Lines, 4. Clinical Characteristics of the patients with Non-B Non-C Hepatocellular Carcinoma and Frequency of HBV, HCV and TTV Viremia in these Patients, 5. Significance of serum iron and ferritin in patients with stomach cancer, 6. Telomerase assay for early detection of lung cancer, 7. Study on the Usefulness of Aldehyde dehydrogenase-2 Genotyping for Risk Group of Alcohol-related Cancer Screening, 8. Gene therapy using hepatoma specific promoter, 9. Study on the Influence of DNA repair gene, XRCC1 Genotypes on the Risk of Head and Neck Cancer were performed.

  4. Basic research on cancer related to radiation associated medical researches

    International Nuclear Information System (INIS)

    Lee, Jong In; Hwang, Dae Yong; Bang, Ho Yoon

    2000-12-01

    Basic Research on Cancer related to Radiation Associated Medical Researches including 1. Establishment of animal model of colorectal cancer liver metastasis and measurement of angiogenesis, 2. Tissue expression of Tie-1 and Tie-2 in human colorectal cancer, 3. Enhancement of G2/Mphase Cell Fraction by Adenovirus-mediated p53 Gene Transfer in Ovarian Cancer Cell Lines, 4. Clinical Characteristics of the patients with Non-B Non-C Hepatocellular Carcinoma and Frequency of HBV, HCV and TTV Viremia in these Patients, 5. Significance of serum iron and ferritin in patients with stomach cancer, 6. Telomerase assay for early detection of lung cancer, 7. Study on the Usefulness of Aldehyde dehydrogenase-2 Genotyping for Risk Group of Alcohol-related Cancer Screening, 8. Gene therapy using hepatoma specific promoter, 9. Study on the Influence of DNA repair gene, XRCC1 Genotypes on the Risk of Head and Neck Cancer were performed

  5. An Institutional Approach to Developing Research Data Management Infrastructure

    Directory of Open Access Journals (Sweden)

    James A. J. Wilson

    2011-10-01

    Full Text Available This article outlines the work that the University of Oxford is undertaking to implement a coordinated data management infrastructure. The rationale for the approach being taken by Oxford is presented, with particular attention paid to the role of each service division. This is followed by a consideration of the relative advantages and disadvantages of institutional data repositories, as opposed to national or international data centres. The article then focuses on two ongoing JISC-funded projects, ‘Embedding Institutional Data Curation Services in Research’ (Eidcsr and ‘Supporting Data Management Infrastructure for the Humanities’ (Sudamih. Both projects are intra-institutional collaborations and involve working with researchers to develop particular aspects of infrastructure, including: University policy, systems for the preservation and documentation of research data, training and support, software tools for the visualisation of large images, and creating and sharing databases via the Web (Database as a Service.

  6. Irradiation Facilities of the Takasaki Advanced Radiation Research Institute

    Directory of Open Access Journals (Sweden)

    Satoshi Kurashima

    2017-03-01

    Full Text Available The ion beam facility at the Takasaki Advanced Radiation Research Institute, the National Institutes for Quantum and Radiological Science and Technology, consists of a cyclotron and three electrostatic accelerators, and they are dedicated to studies of materials science and bio-technology. The paper reviews this unique accelerator complex in detail from the viewpoint of its configuration, accelerator specification, typical accelerator, or irradiation technologies and ion beam applications. The institute has also irradiation facilities for electron beams and 60Co gamma-rays and has been leading research and development of radiation chemistry for industrial applications in Japan with the facilities since its establishment. The configuration and utilization of those facilities are outlined as well.

  7. 75 FR 8374 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-02-24

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research Institute Special... Officer, Scientific Review Branch, National Human Genome Research Institute, National Institutes of Health...

  8. 77 FR 71604 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-12-03

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research Institute Special..., Scientific Review Branch, National Human Genome Research Institute, National Institutes of Health, 5635...

  9. [Researches' Institutional Framework in Three Sub-Saharan African Countries].

    Science.gov (United States)

    Kedoté, N M; Salami, A; Tsala Tsala, J P; Grimaud, M A; Bergeron, M; Fayomi, Benjamin

    2017-05-22

    This paper presents the overview of the legal and institutional frameworks of research with human beings in sub-Saharan Africa, in particular in Benin, Cameroon and Nigeria. Concerning the methodology, a literature review focused on the regulations of institutional frameworks was done. Then, 28 semi-structured interviews were conducted with members of ethics committees to assess their composition and their mode of operation. Finally, we describe the existing courses in research ethics included in programs of first, second and third cycles in major universities from concerned countries.Concerning structures, all countries have normative and functional ethics committees concerned with the basics of ethics in health research. However, these ethics committees face several challenges including the lack of funding, deficiencies in the training of their members and the application of the ethical evaluation to qualitative and mixed researches.

  10. NATO Advanced Research Institute on the Efficiency of Manufacturing Systems

    CERN Document Server

    Berg, C; French, D

    1983-01-01

    The Advanced Research Institute (A.R. 1.) on "the efficiency of Manufacturing Systems" was held under the auspices of the NATO Special Programm~ Panel on Systems Science as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international co-operation. Advanced Research Institutes are organised for the purpose of bringing together experts in a particular field of interest to identify and make known the present state of knowledge in that area and, through informed debate, to make recommendations for directions for future research that would benefit the community at large. To this end two kinds of contribution were obtained by invitation. There were those papers which were about the current state of work in the area of manufacturing systems and its organisation; in addition three theme papers were presented to provide a stimulus to the discussion in terms of ways of thinking, both about the area and about the kind of research needed.

  11. Fraunhofer Institute for Atmospheric Environmental Research. Annual report 1990

    International Nuclear Information System (INIS)

    1991-01-01

    This progress report submitted by Fraunhofer Institut fuer Atmosphaerische Umweltforschung, Garmisch-Partenkirchen, reviews the institute's scientific and technical atmospheric environmental research activities of 1990. Emphasis was on research into the atmospheric circulation of CH 4 and N 2 O, the determination of the distribution and of the time characteristics of trace substances of environmental relevance, and on studies of the effects of pollutants on the vegetation. Major efforts went into the development of instruments and the modeling of the atmosphere in support of the experimental work. The FhG activities advance the research into the chemical behavior of the atmosphere, the possible effects of man-made changes in the chemical composition of the atmosphere on the greenhouse effect, the regional pollutant loads, and the effects of ground-level UV-B radiation. The activities are part of international and national joint research projects, e.g. EUROTRAC, IGAC, and ICAT. (orig./KW) [de

  12. Knowledge synthesis and the Canadian Institutes of Health Research

    Directory of Open Access Journals (Sweden)

    Graham Ian D

    2012-02-01

    Full Text Available Abstract The Canadian Institutes of Health Research (CIHR is Canada's premier health-research funding agency. We fund nearly 14,000 researchers and trainees in four theme areas: biomedical, clinical, health services, and population and public-health research. Our mandate is 'to excel according to international standards of scientific excellence, in the creation of new knowledge and its translation into improved health for Canadians, more effective health services and products and a strengthened Canadian health care system'. Knowledge synthesis is a key element of the knowledge-translation objectives of CIHR, as outlined in our definition of knowledge-translation.

  13. Physical protection of radioactive materials in a University Research Institute

    International Nuclear Information System (INIS)

    Boeck, H.

    1998-01-01

    Although nuclear research centers attached to universities usually do not keep large inventories of radioactive or special nuclear material, the mentioned material has still to be under strict surveillance and safeguards if applicable. One problem in such research centers is the large and frequent fluctuation of persons - mainly students, scientists or visiting guest scientists - using such materials for basic or applied research. In the present paper an overview of protective actions in such a research institute will be given and experience of more than 36 years will be presented. (author)

  14. Office of Institutional Research Transactional System. A Manual.

    Science.gov (United States)

    Black, Frank S.

    1976-01-01

    A transactional system is the routine method for carrying out certain processes. This paper describes how a transactional system can be developed and operated for an office that has no computer support. The model is an Office of Institutional Research (OIR). The OIR manual (noncomputer supported) transactional system at Texas Southern University…

  15. The Netherlands Institute for Social Research | SCP at a glance

    NARCIS (Netherlands)

    2009-01-01

    The Netherlands Institute for Social Research supplies central government with information on the Dutch welfare state. For more than 30 years, the SCP has been charting developments in the daily lives of the Dutch population: work, income, health, education, social security, housing, culture, how

  16. Effective Reporting. Resources in Institutional Research, Number 12.

    Science.gov (United States)

    Bers, Trudy H.

    This monograph is a guide to effective presentation of report data and information from institutional research. The work focuses on several types of presentation: the written report (alternative ways for presenting information, appearance, and the audience); graphic displays or charts (to present words or data in an organized or symbolic fashion;…

  17. Cooperative Institute for Research in the Atmosphere (CIRA) Requirements Review

    Energy Technology Data Exchange (ETDEWEB)

    Zurawski, Jason, W; Mace, Kathryn, P

    2016-08-11

    In August 2016 The Energy Sciences Network (ESnet) and Colorado State University (CSU) organized a review to characterize the networking requirements of the Cooperative Institute for Research in the Atmosphere (CIRA) located on the campus of Colorado State University. Several key findings highlighting the results from the review were discovered, with benefits to improve the overall scientific process for CIRA and CSU.

  18. Research at Private Higher Education Institutions in South Africa

    Science.gov (United States)

    Deacon, Roger; van Vuuren, Rex; Augustyn, Dave

    2014-01-01

    Very little is known about whether and what kinds of research are being undertaken at private higher education institutions (PHEIs) in South Africa. This article draws on a recent survey of all registered PHEIs undertaken by a group of interested private higher education providers. This survey was facilitated by the Council on Higher Education…

  19. Brazilian Institute for Ecological Research: Teaching and applying ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-05-10

    May 10, 2011 ... In reflecting on her experience at IEF 2008, Dr Suzana Padua, president of the Brazilian Institute for Ecological Research (IPE) said: “The more you understand the interconnection of everything that is alive in the planet, then it has to touch you somehow.”As an environmental educator, “[health] is not my ...

  20. Aging in France: Population Trends, Policy Issues, and Research Institutions

    Science.gov (United States)

    Beland, Daniel; Durandal, Jean-Philippe Viriot

    2013-01-01

    Like in other advanced industrial countries, in France, demographic aging has become a widely debated research and policy topic. This article offers a brief overview of major aging-related trends in France. The article describes France's demographics of aging, explores key policy matters, maps the institutional field of French social gerontology…

  1. Institutional Support: Centre for Economic and Social Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Institutional Support: Centre for Economic and Social Research, Education and Documentation (Burkina Faso). The Centre d'études de documentation et de recherches ... anticipated GrowInclusive Platform now under construction. IDRC partner the World Economic Forum is building a hub for inclusive growth solutions.

  2. Guides to Pollution Prevention: Research and Educational Institutions.

    Science.gov (United States)

    Environmental Protection Agency, Cincinnati, OH. Office of Research and Development.

    This guide provides an overview of waste generating processes and operations that occur in educational or research institutions and presents options for minimizing waste generation through source reduction and recycling. A broad spectrum of waste chemicals in laboratories, art studios, print shops, maintenance, and other operations can be…

  3. Summer Research Institute Interfacial and Condensed Phase Chemical Physics

    Energy Technology Data Exchange (ETDEWEB)

    Barlow, Stephan E.

    2004-10-01

    Pacific Northwest National Laboratory (PNNL) hosted its first annual Summer Research Institute in Interfacial and Condensed Phase Chemical Physics from May through September 2004. During this period, fourteen PNNL scientists hosted sixteen young scientists from eleven different universities. Of the sixteen participants, fourteen were graduate students; one was transitioning to graduate school; and one was a university faculty member.

  4. Research Review of the Institute of African Studies: Contact

    African Journals Online (AJOL)

    Principal Contact. Prof. M.E. Kropp Dakubu Editor-in-Chief University of Ghana. Research Review. Institute of African Studies. P.O.Box LG73 Legon, Ghana. Phone: 211-24-4764006. Fax: 233-21-500512. Email: medakubu@ug.edu.gh. Support Contact. Dr Stephen Acheampong Phone: 211-24-4979233

  5. Developing institutional repository at National Institute for Materials Science : Researchers directory service “SAMURAI” and Research Collection Library

    Science.gov (United States)

    Takaku, Masao; Tanifuji, Mikiko

    National Institute for Materials Science (NIMS) has developed an institutional repository “NIMS eSciDoc” since 2008. eSciDoc is an open source repository software made in Germany, and provides E-Science infrastructures through its flexible data model and rich Web APIs. NIMS eScidoc makes use of eSciDoc functions to benefit for NIMS situations. This article also focuses on researchers directory service “SAMURAI” in addition to NIMS eSciDoc. Successfully launched in October 2010, SAMURAI provides approximately 500 researchers' profile and publication information.

  6. Joint Institute for Nuclear Research Exhibition Science Bringing Nations Together

    CERN Multimedia

    2000-01-01

    The JOINT INSTITUTE FOR NUCLEAR RESEARCH, JINR, was established by its founding countries in 1956 with the purpose of joining together the scientific and material potential of Member States in studies of the fundamental properties of matter. JINR is an international inter-governmental scientific research organization, whose activities are based on the principles of openness for participation to all interested states and of their equal, mutually beneficial collaboration.

  7. A platform for quality management in research institutes (part II

    Directory of Open Access Journals (Sweden)

    Klembalska Agnieszka

    2016-09-01

    Full Text Available In the recent years there has been a particularly strong pressure on changing old structures and management models in research institutes. Contemporary research institutes are scientific units which are commercial in character – almost 80% of funds come from companies and contractual research activity and services. They are the basic sector of science aiming at cooperation with the economy, applied and innovative research. In order to maintain the current and start new cooperation it is necessary to pay particular attention to maintaining, improving and exposing high level of quality of conducted activity. Taking into consideration the necessity of carrying out ever more complex research projects, conducting activity requiring fast reaction to change, risk analysis, which is assessed every year by the Ministry of Science and Higher Education – it seems that it is necessary to apply tools supporting the assessment of quality. In the proposed three-aspect perspective the following scopes of activity are emphasized: implemented quality management systems, area of scientific information and the sphere of cooperation with the client. This article constitutes the continuation of the subjects discussed in the first part – an extension of issues associated with the scope of responsibilities of particular Sections of the proposed Quality Management Platform in research institutes.

  8. Prostate Cancer Research Training Program

    Science.gov (United States)

    2014-05-01

    how chromatin structure participates in the transcriptional regulation of cancer related genes including oncogenes and tumor suppressor genes...signaling pathways related to cancer progression to various approaches for therapeutic intervention in these pathways including large molecule...diseases, focused on molecular epidemiology, HPV effects on the development of genital and other cancers ; hormones and risk of HPV detection and

  9. Lysyl oxidase in cancer research

    DEFF Research Database (Denmark)

    Perryman, Lara; Erler, Janine Terra

    2014-01-01

    Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target. In this review we...

  10. Accelerating cancer systems biology research through Semantic Web technology.

    Science.gov (United States)

    Wang, Zhihui; Sagotsky, Jonathan; Taylor, Thomas; Shironoshita, Patrick; Deisboeck, Thomas S

    2013-01-01

    Cancer systems biology is an interdisciplinary, rapidly expanding research field in which collaborations are a critical means to advance the field. Yet the prevalent database technologies often isolate data rather than making it easily accessible. The Semantic Web has the potential to help facilitate web-based collaborative cancer research by presenting data in a manner that is self-descriptive, human and machine readable, and easily sharable. We have created a semantically linked online Digital Model Repository (DMR) for storing, managing, executing, annotating, and sharing computational cancer models. Within the DMR, distributed, multidisciplinary, and inter-organizational teams can collaborate on projects, without forfeiting intellectual property. This is achieved by the introduction of a new stakeholder to the collaboration workflow, the institutional licensing officer, part of the Technology Transfer Office. Furthermore, the DMR has achieved silver level compatibility with the National Cancer Institute's caBIG, so users can interact with the DMR not only through a web browser but also through a semantically annotated and secure web service. We also discuss the technology behind the DMR leveraging the Semantic Web, ontologies, and grid computing to provide secure inter-institutional collaboration on cancer modeling projects, online grid-based execution of shared models, and the collaboration workflow protecting researchers' intellectual property. Copyright © 2012 Wiley Periodicals, Inc.

  11. Minority Institutions Collaboration in Geoscience Education and Research

    Science.gov (United States)

    Morris, P. A.; Austin, S. A.; Johnson, L. P.; Salgado, C.; Walter, D. K.

    2007-12-01

    The Minority University Consortium for Earth and Space Sciences (MUCESS) is a collaboration among four diverse minority institutions to increase the number of underrepresented students pursuing professional and research careers in Earth and Atmospheric Science and Space Science. The institutions that comprise MUCESS include the University of Houston-Downtown (Hispanic Serving Institution), Medgar Evers College (Other Minority University), Norfolk State University (Historically Black College/University) and South Carolina State University (Historically Black College/University). MUCESS collaborations span a range of projects in research, education and outreach in Earth and Space Science. This includes faculty research, undergraduate internships and student exchanges among our institutions as well as outreach to K-12 schools and the general public. MUCESS has recently received an award from the National Science Foundation under Solicitation NSF 04-590 "Opportunities for Enhancing Diversity in the Geosciences (OEDG)". Under this award faculty and students will be engaged in research (both undergraduate and graduate) in atmospheric science through ozonesonde launches to better understand the distribution and transport of ozone in the lower troposphere. Faculty and students will also participate in ozone observations for validation of instruments onboard the NASA Aura satellite. Additional balloon payloads will include instruments such as temperature and data logger sensors, carbon dioxide detectors, Geiger counters and digital and analog cameras. Launches will originate from Texas, New York, Vermont, South Carolina and elsewhere. This presentation describes the formation of MUCESS and the collaborative undergraduate research and outreach projects spanning six or more years. It also describes the evolution of the joint ozone investigation as well as planned activities supported by the NSF Geoscience Diversity award. Funding for the work described has been provided by

  12. Demographic pattern of male breast cancer: an institutional based study

    International Nuclear Information System (INIS)

    Tanseem, S.; Khan, M.M.; Khan, M.M.K.

    2011-01-01

    Background: Male breast cancer incidence rises with age with peak in the sixth and seventh decade. It is one of the rare diseases and accounts for less than 1% of all malignancies worldwide. It is usually diagnosed in the late stage with poor prognosis. Objective: The purpose of this study was to know the demographic pattern and tumour characteristic of breast cancer in men reported at Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar. Methods: Retrospective data was collected from the (IRNUM), Peshawar for a period of three years (2006-2008). The evaluation was done from the histopathological reports of mastectomy and biopsy specimens. All male patients in the age group 26 -86 year with breast cancer were included in the study. The age of the patients and tumour characteristics recorded were size, grade, type, skin involvement and stage. Results: Total number of male patients with breast cancer were 31 (2.1%) out of the total patients with breast malignancy during the study period with the mean age of 58.3 years. Tumour size ranged from 2 to 12 Cm. with average of 3.6 Cm. Invasive ductal carcinoma was found in 87% , papillary carcinoma in 6.5%, each of malignant fibrous histocytoma and sarcoma in 3.2% cases. Maximum number of patients was of grade II (41%). Patients in whom stage of the disease was know n were 22 cases with 45.5% had stage III disease and 32% had stage IV disease. Skin involvement was found positive in 8 (25.8%). Conclusion: Due to poor health care system breast cancer is diagnosed in a late stage of the disease and prognosis is poor. (author)

  13. Pioneering the Transdisciplinary Team Science Approach: Lessons Learned from National Cancer Institute Grantees

    Science.gov (United States)

    Vogel, Amanda L; Stipelman, Brooke A; Hall, Kara L; Nebeling, Linda; Stokols, Daniel; Spruijt-Metz, Donna

    2014-01-01

    The National Cancer Institute has been a leader in supporting transdisciplinary (TD) team science. From 2005-2010, the NCI supported Transdisciplinary Research on Energetic and Cancer I (TREC I), a center initiative fostering the TD integration of social, behavioral, and biological sciences to examine the relationships among obesity, nutrition, physical activity and cancer. In the final year of TREC I, we conducted qualitative in-depth-interviews with 31 participating investigators and trainees to learn more about their experiences with TD team science, including challenges, facilitating factors, strategies for success, and impacts. Five main challenges emerged: (1) limited published guidance for how to engage in TD team science, when TREC I was implemented; (2) conceptual and scientific challenges inherent to efforts to achieve TD integration; (3) discipline-based differences in values, terminology, methods, and work styles; (4) project management challenges involved in TD team science; and (5) traditional incentive and reward systems that do not recognize or reward TD team science. Four main facilitating factors and strategies for success emerged: (1) beneficial attitudes and beliefs about TD research and team science; (2) effective team processes; (3) brokering and bridge-building activities by individuals holding particular roles in a research center; and (4) funding initiative characteristics that support TD team science. Broad impacts of participating in TD team science in the context of TREC I included: (1) new positive attitudes about TD research and team science; (2) new boundary-crossing collaborations; (3) scientific advances related to research approaches, findings, and dissemination; (4) institutional culture change and resource creation in support of TD team science; and (5) career advancement. Funding agencies, academic institutions, and scholarly journals can help to foster TD team science through funding opportunities, institutional policies on

  14. Pioneering the Transdisciplinary Team Science Approach: Lessons Learned from National Cancer Institute Grantees.

    Science.gov (United States)

    Vogel, Amanda L; Stipelman, Brooke A; Hall, Kara L; Nebeling, Linda; Stokols, Daniel; Spruijt-Metz, Donna

    2014-01-01

    The National Cancer Institute has been a leader in supporting transdisciplinary (TD) team science. From 2005-2010, the NCI supported Transdisciplinary Research on Energetic and Cancer I (TREC I), a center initiative fostering the TD integration of social, behavioral, and biological sciences to examine the relationships among obesity, nutrition, physical activity and cancer. In the final year of TREC I, we conducted qualitative in-depth-interviews with 31 participating investigators and trainees to learn more about their experiences with TD team science, including challenges, facilitating factors, strategies for success, and impacts. Five main challenges emerged: (1) limited published guidance for how to engage in TD team science, when TREC I was implemented; (2) conceptual and scientific challenges inherent to efforts to achieve TD integration; (3) discipline-based differences in values, terminology, methods, and work styles; (4) project management challenges involved in TD team science; and (5) traditional incentive and reward systems that do not recognize or reward TD team science. Four main facilitating factors and strategies for success emerged: (1) beneficial attitudes and beliefs about TD research and team science; (2) effective team processes; (3) brokering and bridge-building activities by individuals holding particular roles in a research center; and (4) funding initiative characteristics that support TD team science. Broad impacts of participating in TD team science in the context of TREC I included: (1) new positive attitudes about TD research and team science; (2) new boundary-crossing collaborations; (3) scientific advances related to research approaches, findings, and dissemination; (4) institutional culture change and resource creation in support of TD team science; and (5) career advancement. Funding agencies, academic institutions, and scholarly journals can help to foster TD team science through funding opportunities, institutional policies on

  15. The role of research and research institutes in fisheries development in the 1980's

    OpenAIRE

    Sagua, V.O.

    1986-01-01

    An indication is given as to areas in Nigerian fisheries development which require research in the 1980's: fish resource surveys, fishing technology, fish processing and preservation technology, and aquaculture. The role of research institutes is also considered

  16. Alliance Against Cancer, the network of Italian cancer centers bridging research and care.

    Science.gov (United States)

    De Paoli, Paolo; Ciliberto, Gennaro; Ferrarini, Manlio; Pelicci, PierGiuseppe; Dellabona, Paolo; De Lorenzo, Francesco; Mantovani, Alberto; Musto, Pellegrino; Opocher, Giuseppe; Picci, Piero; Ricciardi, Walter; De Maria, Ruggero

    2015-11-14

    Alliance Against Cancer (ACC) was established in Rome in 2002 as a consortium of six Italian comprehensive cancer centers (Founders). The aims of ACC were to promote a network among Italian oncologic institutions in order to develop specific, advanced projects in clinical and translational research. During the following years, many additional full and associate members joined ACC, that presently includes the National Institute of Health, 17 research-oriented hospitals, scientific and patient organizations. Furthermore, in the last three years ACC underwent a reorganization process that redesigned the structure, governance and major activities. The present goal of ACC is to achieve high standards of care across Italy, to implement and harmonize principles of modern personalized and precision medicine, by developing cost effective processes and to provide tailored information to cancer patients. We herein summarize some of the major initiatives that ACC is currently developing to reach its goal, including tumor genetic screening programs, establishment of clinical trial programs for cancer patients treated in Italian cancer centers, facilitate their access to innovative drugs under development, improve quality through an European accreditation process (European Organization of Cancer Institutes), and develop international partnerships. In conclusion, ACC is a growing organization, trying to respond to the need of networking in Italy and may contribute significantly to improve the way we face cancer in Europe.

  17. PROGER - radioactive waste management in Brazilian research institutions

    International Nuclear Information System (INIS)

    Pontedeiro, E.; Ramos, A.C.; Reis e Vaz, S.; Ferreira, R.S.

    1998-01-01

    This article demonstrates the feasibility of a programme, called PROGER, which is aimed at improving the radioactive waste management activities of research institutions in Brazil. PROGER involves the implementation, correction and updating of waste management techniques in those institutions where a waste management system is already being carried out or the introduction and full deployment of such a system in those where a system does not exist. The methodology utilized by the PROGER programme is discussed, and partial results are presented bearing in mind the characteristics and quantities of wastes. (author)

  18. Research Institute ITAL. Association EURATOM ITAL. Annual report 1982

    International Nuclear Information System (INIS)

    1983-01-01

    The Research Institute ITAL is one of the institutes of the Division for Agricultural Research of the Dutch Ministry of Agriculture and Fisheries. For certain aspects of its programme it is also a partner in the Association EURATOM-ITAL with the Commission of the European Community. This annual report deals with: molecular genetic methods for plant breeding; biotechnical production of valuable compounds by means of (plant) cell cultures and microorganisms; soil biology including the rhizosphere; radioactive contamination of the environment and its public health risks; the synergistic interaction between radiation and other mutagenic agents; a new approach in malaria control by means of radiation genetic research on insects; genetic sexing in the Mediterranean fruitfly, Ceratitis capitata; food irradiation (activities within the contract of the Dutch Government with the IAEA in Vienna and the FAO in Rome on food irradiation technology for developing countries). (Auth.)

  19. Metrics-based assessments of research: incentives for 'institutional plagiarism'?

    Science.gov (United States)

    Berry, Colin

    2013-06-01

    The issue of plagiarism--claiming credit for work that is not one's own, rightly, continues to cause concern in the academic community. An analysis is presented that shows the effects that may arise from metrics-based assessments of research, when credit for an author's outputs (chiefly publications) is given to an institution that did not support the research but which subsequently employs the author. The incentives for what is termed here "institutional plagiarism" are demonstrated with reference to the UK Research Assessment Exercise in which submitting units of assessment are shown in some instances to derive around twice the credit for papers produced elsewhere by new recruits, compared to papers produced 'in-house'.

  20. The Armstrong Institute: An Academic Institute for Patient Safety and Quality Improvement, Research, Training, and Practice.

    Science.gov (United States)

    Pronovost, Peter J; Holzmueller, Christine G; Molello, Nancy E; Paine, Lori; Winner, Laura; Marsteller, Jill A; Berenholtz, Sean M; Aboumatar, Hanan J; Demski, Renee; Armstrong, C Michael

    2015-10-01

    Academic medical centers (AMCs) could advance the science of health care delivery, improve patient safety and quality improvement, and enhance value, but many centers have fragmented efforts with little accountability. Johns Hopkins Medicine, the AMC under which the Johns Hopkins University School of Medicine and the Johns Hopkins Health System are organized, experienced similar challenges, with operational patient safety and quality leadership separate from safety and quality-related research efforts. To unite efforts and establish accountability, the Armstrong Institute for Patient Safety and Quality was created in 2011.The authors describe the development, purpose, governance, function, and challenges of the institute to help other AMCs replicate it and accelerate safety and quality improvement. The purpose is to partner with patients, their loved ones, and all interested parties to end preventable harm, continuously improve patient outcomes and experience, and eliminate waste in health care. A governance structure was created, with care mapped into seven categories, to oversee the quality and safety of all patients treated at a Johns Hopkins Medicine entity. The governance has a Patient Safety and Quality Board Committee that sets strategic goals, and the institute communicates these goals throughout the health system and supports personnel in meeting these goals. The institute is organized into 13 functional councils reflecting their behaviors and purpose. The institute works daily to build the capacity of clinicians trained in safety and quality through established programs, advance improvement science, and implement and evaluate interventions to improve the quality of care and safety of patients.

  1. Confronting Ambiguity, Anarchy, and Crisis in Institutional Research: Using Student Unit Record Databases in Extra-Institutional Research

    Science.gov (United States)

    Musoba, Glenda D.; Gross, Jacob P. K.; Hossler, Don

    2008-01-01

    The world of policymaking on the campuses of colleges and universities is messy, ambiguous, and contested. In this complex environment, which Kingdon (2003) has aptly called a "policy soup," the role of institutional research is often not only to provide answers to existing policy questions but to produce information to help transform…

  2. Skoda Concern's cooperation with State Machinery Design Research Institute

    International Nuclear Information System (INIS)

    Valchar, J.; Kuhn, L.

    1988-01-01

    The main areas are presented of cooperation between the Skoda Plzen Concern and the State Machinery Design Research Institute in Prague-Bechovice. This is mainly the development of steam turbines, from 50 MW turbines to the present 1000 MW saturated steam turbines designed for nuclear power plants. Main attention is centred on conditions of the boiling crisis in the steam turbine circuit, and its consequences. This study is served by the experimental equipment of the institute and its computer. The cooperation of the two institutions in the field of testing and diagnostic equipment is centred on measuring natural oscillations of turbine blades, the diagnostics of vibrations of steam turbines, the measurement of the humidity of saturated steam, optical measurements of the parameters of saturated steam, ultrasound diagnostics and the measurement of turbine blade deformation caused by hydraulic effects. (Z.M.). 8 figs

  3. Institutional Research and Development: [Annual report], FY 1986

    International Nuclear Information System (INIS)

    Strack, B.

    1987-01-01

    The Institutional Research and Development (IR and D) program was established at the Lawrence Livermore National Laboratory (LLNL) by the Director in October 1984. The IR and D program fosters exploratory work to advance science and technology; disciplinary research to create varied, innovative approaches to selected scientific fields; and long-term research in support of the defense and energy missions at LLNL. Each project in the IR and D program was selected after personal interviews by the Director and his delegates and was deemed to show unusual promise. These projects include research in the following fields: chemistry and materials science, computation, earth sciences, engineering, nuclear chemistry, biotechnology, environmental consequences of nuclear war, geophysics and planetary physics, and supercomputer research and development. A separate section of the report is devoted to research projects receiving individual awards

  4. Institutional Research and Development: (Annual report), FY 1986

    Energy Technology Data Exchange (ETDEWEB)

    Strack, B. (ed.)

    1987-01-01

    The Institutional Research and Development (IR and D) program was established at the Lawrence Livermore National Laboratory (LLNL) by the Director in October 1984. The IR and D program fosters exploratory work to advance science and technology; disciplinary research to create varied, innovative approaches to selected scientific fields; and long-term research in support of the defense and energy missions at LLNL. Each project in the IR and D program was selected after personal interviews by the Director and his delegates and was deemed to show unusual promise. These projects include research in the following fields: chemistry and materials science, computation, earth sciences, engineering, nuclear chemistry, biotechnology, environmental consequences of nuclear war, geophysics and planetary physics, and supercomputer research and development. A separate section of the report is devoted to research projects receiving individual awards.

  5. The 2017 Nonlinear Mechanics and Dynamics Research Institute.

    Energy Technology Data Exchange (ETDEWEB)

    Kuether, Robert J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Allensworth, Brooke Marie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Peebles, Diane E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2018-02-01

    The 2017 Nonlinear Mechanics and Dynamics (NOMAD) Research Institute was successfully held from June 19 to July 28, 2017. NOMAD seeks to bring together participants with diverse tec hnical backgrounds to work in small teams to utilize an interactive approach to cultivate new ideas and approaches in engineering . NOMAD provides an opportunity for researchers - especially early career researchers - to develop lasting collaborations that go beyond what can be established from the limited interactions at their institutions or at annual conferences. A total of 17 students from around the world came to Albuquerque, New Mexico to participate in the six - week long program held at the University of New Mexico campus. The students collaborated on one of six research projects that were developed by various mentors from Sandia National Laboratories, academia, and other government laboratories. In addition to the research activities, the students atte nded weekly technical seminars, toured the National Museum of Nuclear Science & History, and socialized at various off - hour events including an Albuquerque Isotopes baseball game. At the end of the summer, the students gave a final technical presentation o n their research findings that was broadcast via Skype. Many of the research discoveries made at NOMAD are published as proceedings at t echnical conference s and have direct alignment with the critical mission work performed at Sandia.

  6. Geothermal studies at the University of Utah Research Institute

    Energy Technology Data Exchange (ETDEWEB)

    None

    1988-07-01

    The University of Utah Research Institute (WRI) is a self-supporting corporation organized in December 1972 under the Utah Non-Profit Corporation Association Act. Under its charter, the Institute is separate in its operations and receives no direct financial support from either the University of Utah or the State of Utah. The charter includes provisions for WRI to conduct both public and proprietary scientific work for governmental agencies, academic institutions, private industry, and individuals. WRI is composed of five divisions, shown in Figure 1: the Earth Science Laboratory (ESL), the Environmental Studies Laboratory (EVSL), the Center for Remote Sensing and Cartography (CRSC), the Engineering Technology Laboratory (ETL) and the Atmospheric Physics Laboratory (APL). The Earth Science Laboratory has a staff of geologists, geochemists and geophysicists who have a broad range of experience in geothermal research and field projects as well as in mineral and petroleum exploration. The Environmental Studies Laboratory offers a variety of technical services and research capabilities in the areas of air quality and visibility, acid precipitation, surface and groundwater contamination, and environmentally caused stress in vegetation. The Center for Remote Sensing and Cartography offers applied research and services with a full range of remote sensing and mapping capability, including satellite and airborne imagery processing and interpretation. The Engineering Technology Laboratory is currently studying the interaction of the human body with electromagnetic radiation. The Atmospheric Physics Laboratory is developing hygroscopic droplet growth theory and orographic seeding models for dispersal of fog.

  7. Predoctoral Training Program in Breast Cancer Research

    National Research Council Canada - National Science Library

    Stern, David F

    2004-01-01

    .... This means that research on breast cancer has finally advanced to the stage where a concentrated effort in translational research will yield great strides in detection, diagnosis, and treatment...

  8. Cancer Biotechnology | Center for Cancer Research

    Science.gov (United States)

    Biotechnology advances continue to underscore the need to educate NCI fellows in new methodologies. The Cancer Biotechnology course will be held on the NCI-Frederick campus on January 29, 2016 (Bldg. 549, Main Auditorium) and the course will be repeated on the Bethesda campus on February 9, 2016 (Natcher Balcony C). The latest advances in DNA, protein and image analysis will be presented. Clinical and postdoctoral fellows who want to learn about new biotechnology advances are encouraged to attend this course.

  9. Developing a Comprehensive Cardio-Oncology Program at a Cancer Institute: The Moffitt Cancer Center Experience

    Science.gov (United States)

    Fradley, Michael G.; Brown, Allen C.; Shields, Bernadette; Viganego, Federico; Damrongwatanasuk, Rongras; Patel, Aarti A.; Hartlage, Gregory; Roper, Natalee; Jaunese, Julie; Roy, Larry; Ismail-Khan, Roohi

    2017-01-01

    Cardio-oncology is a multidisciplinary field focusing on the management and prevention of cardiovascular complications in cancer patients and survivors. While the initial focus of this specialty was on heart failure associated with anthracycline use, novel anticancer agents are increasingly utilized and are associated with many other cardiotoxicities including hypertension, arrhythmias and vascular disease. Since its inception, the field has developed at a rapid pace with the establishment of programs at many major academic institutions and community practices. Given the complexities of this patient population, it is important for providers to possess knowledge of not only cardiovascular disease but also cancer subtypes and their specific therapeutics. Developing a cardio-oncology program at a stand-alone cancer center can present unique opportunities and challenges when compared to those affiliated with other institutions including resource allocation, cardiovascular testing availability and provider education. In this review, we present our experiences establishing the cardio-oncology program at Moffitt Cancer Center and provide guidance to those individuals interested in developing a program at a similar independent cancer institution. PMID:28781723

  10. Developing a Comprehensive Cardio-Oncology Program at a Cancer Institute: The Moffitt Cancer Center Experience.

    Science.gov (United States)

    Fradley, Michael G; Brown, Allen C; Shields, Bernadette; Viganego, Federico; Damrongwatanasuk, Rongras; Patel, Aarti A; Hartlage, Gregory; Roper, Natalee; Jaunese, Julie; Roy, Larry; Ismail-Khan, Roohi

    2017-06-14

    Cardio-oncology is a multidisciplinary field focusing on the management and prevention of cardiovascular complications in cancer patients and survivors. While the initial focus of this specialty was on heart failure associated with anthracycline use, novel anticancer agents are increasingly utilized and are associated with many other cardiotoxicities including hypertension, arrhythmias and vascular disease. Since its inception, the field has developed at a rapid pace with the establishment of programs at many major academic institutions and community practices. Given the complexities of this patient population, it is important for providers to possess knowledge of not only cardiovascular disease but also cancer subtypes and their specific therapeutics. Developing a cardio-oncology program at a stand-alone cancer center can present unique opportunities and challenges when compared to those affiliated with other institutions including resource allocation, cardiovascular testing availability and provider education. In this review, we present our experiences establishing the cardio-oncology program at Moffitt Cancer Center and provide guidance to those individuals interested in developing a program at a similar independent cancer institution.

  11. Developing a comprehensive Cardio-Oncology Program at a Cancer Institute: the Moffitt Cancer Center experience

    Directory of Open Access Journals (Sweden)

    Michael G. Fradley

    2017-07-01

    Full Text Available Cardio-oncology is a multidisciplinary field focusing on the management and prevention of cardiovascular complications in cancer patients and survivors. While the initial focus of this specialty was on heart failure associated with anthracycline use, novel anticancer agents are increasingly utilized and are associated with many other cardiotoxicities including hypertension, arrhythmias and vascular disease. Since its inception, the field has developed at a rapid pace with the establishment of programs at many major academic institutions and community practices. Given the complexities of this patient population, it is important for providers to possess knowledge of not only cardiovascular disease but also cancer subtypes and their specific therapeutics. Developing a cardio- oncology program at a stand-alone cancer center can present unique opportunities and challenges when compared to those affiliated with other institutions including resource allocation, cardiovascular testing availability and provider education. In this review, we present our experiences establishing the cardio-oncology program at Moffitt Cancer Center and provide guidance to those individuals interested in developing a program at a similar independent cancer institution.

  12. Five National Cancer Institute-designated cancer centers' data collection on racial/ethnic minority participation in therapeutic trials: a current view and opportunities for improvement.

    Science.gov (United States)

    Hawk, Ernest T; Habermann, Elizabeth B; Ford, Jean G; Wenzel, Jennifer A; Brahmer, Julie R; Chen, Moon S; Jones, Lovell A; Hurd, Thelma C; Rogers, Lisa M; Nguyen, Lynne H; Ahluwalia, Jasjit S; Fouad, Mona; Vickers, Selwyn M

    2014-04-01

    To ensure that National Institutes of Health-funded research is relevant to the population's needs, specific emphasis on proportional representation of minority/sex groups into National Cancer Institute (NCI) cancer centers' clinical research programs is reported to the NCI. EMPaCT investigators at 5 regionally diverse comprehensive cancer centers compared data reported to the NCI for their most recent Cancer Center Support Grant competitive renewal to assess and compare the centers' catchment area designations, data definitions, data elements, collection processes, reporting, and performance regarding proportional representation of race/ethnicity and sex subsets. Cancer centers' catchment area definitions differed widely in terms of their cancer patient versus general population specificity, levels of specificity, and geographic coverage. Racial/ethnic categories were similar, yet were defined differently, across institutions. Patients' socioeconomic status and insurance status were inconsistently captured across the 5 centers. Catchment area definitions and the collection of patient-level demographic factors varied widely across the 5 comprehensive cancer centers. This challenged the assessment of success by cancer centers in accruing representative populations into the cancer research enterprise. Accrual of minorities was less than desired for at least 1 racial/ethnic subcategory at 4 of the 5 centers. Institutions should clearly and consistently declare their primary catchment area and the rationale and should report how race/ethnicity and sex are defined, determined, collected, and reported. More standardized, frequent, consistent collection, reporting, and review of these data are recommended, as is a commitment to collecting socioeconomic data, given that socioeconomic status is a primary driver of cancer disparities in the United States. © 2014 American Cancer Society.

  13. Environmental dose in the Nuclear Medicine Department of the National Institute of Cancer

    International Nuclear Information System (INIS)

    Torres U, C. L.; Avila A, O. L.; Medina V, L. A.; Buenfil B, A. E.; Brandan S, M. E.; Trujillo Z, F. E.; Gamboa de Buen, I.

    2009-01-01

    The dosimeters TLD-100 and TLD-900 were used to know the levels of environmental dose in areas of the Nuclear Medicine Department of the National Institute of Cancer. The dosimeters calibration was carried out in the Metrology Department of the National Institute of Nuclear Research. The radioisotopes used in the studied areas are 131 I, 18 F, 67 Ga, 99m Tc, 111 In, 201 Tl and 137 Cs with gamma energies between 93 and 662 KeV. Dosimeters were placed during five months in the diagnostic, injection, waiting and PET rooms as well as hot room, waste room, enclosed corridors to patient rooms treated with 131 I and 137 Cs and witness dosimeters to know the bottom. The values found vary between 0.3 and 70 major times that those of bottom. The maximum doses were measured in the waste room and in the enclosed corridor to the patient rooms with cervical uterine cancer treated with 137 Cs. (Author)

  14. System of institutional radioactive waste management in the Nuclear Research Institute Rez plc

    International Nuclear Information System (INIS)

    Podlaha, J.; Burian, P.

    2005-01-01

    The Nuclear Research Institute Rez plc (NRI) is a leading institution in the area of nuclear Research and Development in the Czech Republic. The NRI has had a dominant position in the nuclear programme since it was established in 1955 as a state-owned research organization and it has developed to its current status. In December 1992 the NRI has been transformed into a joint-stock company. The NRI's activity encompasses nuclear physics, chemistry, nuclear power, experiments at the research reactor and many other topics. Main issues addressed in the NRI in the past decades were concentrated on research, development and services provided to the nuclear power plants operating WWER reactors, development of chemical technologies for fuel cycle and irradiation services to research and development in the industrial sector, agriculture, food processing and medicine. At present the research activities are mainly targeted to assist the State Office for Nuclear Safety -the nuclear safety regulating body, power plant operator and nuclear facilities contractors. Significant attention is also paid to the use of nuclear technology outside the nuclear power sector, providing a wide range of services to industry , medicine and the preparation of radiopharmaceuticals. NRI operates two research nuclear reactors and another facilities such as a hot cell facility , research laboratories, technology for radioactive waste (RAW) management, 60 Co irradiators, an electron accelerator, etc. In this paper the Centre of RAW management, system of RAW management, facilities for RAW management as well as decontamination and decommissioning activities of the NRI are presented. The NRI provides complex services in the area of RAW management and has gained many experience and full qualification not only in this area but also in the area of decontamination and decommissioning and spent fuel management. The NRI guarantees safe RAW and spent fuel management. (authors)

  15. The DSM and Professional Practice: Research, Clinical, and Institutional Perspectives.

    Science.gov (United States)

    Halpin, Michael

    2016-06-01

    How mental illnesses are defined has significant ramifications, given the substantial social and individual repercussions of these conditions. Using actor-network theory, I analyze how mental health professionals use the Diagnostic and Statistical Manual of Mental Disorders (DSM) in their work. Drawing on observations of a neuropsychological laboratory and interviews with 27 professionals (i.e., psychiatrists, psychologists), I investigate how the DSM is used in research, clinical, and institutional work. In research, the DSM influences study design and exclusion/inclusion criteria. In the clinic, the DSM influences how disorders are conceptualized and diagnosed. Institutionally, the DSM aligns the patient-professional encounter to insurance and pharmaceutical interests. I conclude that the DSM operates as multiple, context-specific taxonomies that pervasively influence professional practices, such that all possible actions must orient to DSM criteria, with professionals both a source and an object of institutionalized gaze. © American Sociological Association 2016.

  16. The National Institute for Health Research Leadership Programme

    Science.gov (United States)

    Jones, Molly Morgan; Wamae, Watu; Fry, Caroline Viola; Kennie, Tom; Chataway, Joanna

    2012-01-01

    Abstract RAND Europe evaluated the National Institute for Health Research (NIHR) Leadership Programme in an effort to help the English Department of Health consider the extent to which the programme has helped to foster NIHR's aims, extract lessons for the future, and develop plans for the next phase of the leadership programme. Successful delivery of high-quality health research requires not only an effective research base, but also a system of leadership supporting it. However, research leaders are not often given the opportunity, nor do they have the time, to attend formal leadership or management training programmes. This is unfortunate because research has shown that leadership training can have a hugely beneficial effect on an organisation. Therefore, the evaluation has a particular interest in understanding the role of the programme as a science policy intervention and will use its expertise in science policy analysis to consider this element alongside other, more traditional, measures of evaluation. PMID:28083231

  17. Consumer involvement in cancer research: example from a Cancer Network.

    Science.gov (United States)

    Arain, Mubashir; Pyne, Sarah; Thornton, Nigel; Palmer, Susan; Sharma, Ricky A

    2015-10-01

    The involvement of consumers and the general public in improving cancer services is an important component of health services. However, consumer involvement in cancer research is relatively unexplored. The objective of this study was to explore different ways of involving consumers in cancer research in one regional network. Thames Valley Cancer Network Consumer Research Partnership (CRP) group was formed in 2009. The group consists of consumers and professionals to help in promoting consumer involvement in Cancer Research in the Thames Valley. This study evaluated the project of consumer involvement in cancer research in the Thames Valley from March 2010 to March 2011. We used different indices to judge the level of consumer involvement: number of projects involving consumers through the group, types of projects, level of involvement (ranged from consultation on research documents to collaborating in preparing grant applications) and the methods of involving consumers in cancer research. Fifteen projects were submitted to the CRP group during the 12-month period studied. Of these, eight projects were clinical trials, three were qualitative research projects, two were patients' surveys and two were non-randomized interventional studies. Seven projects requested consumer involvement on patient information sheets for clinical trials. Of these seven applications, three also requested consumers' help in designing research questionnaires and another three requested that consumers should be involved in their project management group. In addition, four projects involved consumers in the proposal development phase and another four projects asked for advice on how to increase trial recruitment, conduct patient interviews or help with grant applications. The creation of the CRP and this audit of its activity have documented consumer involvement in cancer research in the Thames Valley. We have clearly shown that consumers can be involved in designing and managing cancer

  18. Challenges facing the marketing of scientific and research institutes

    OpenAIRE

    Bogdan Sojkin

    2015-01-01

    This article presents the challenges that scientific research institutions face in terms of their marketing, which have been divided into two groups of those associated with internal marketing and those linked to external marketing. The most significant and important determinants that constitute challenges to both internal and external marketing were described. The key aspects of each of the identified challenges were indicated, as was their impact on the implementation of the marketing polic...

  19. How EPRI [Electric Power Research Institute] helps utilities save money

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    A number of case studies are presented which illustrate how the work of the Electric Power Research Institute in the USA has enabled nuclear utilities to save money. The areas covered by the examples are: steam generator tube repair; streamlining of reliability centred maintenance; cost effective instrumentation and control maintenance; reducing the frequency of instrument calibration; optimising the engineering change process; detecting and reducing fuel failure; extending the qualified life of equipment. (U.K.)

  20. Governance and Institutions: Proposals for a Research Agenda

    Directory of Open Access Journals (Sweden)

    Francisco Valdés Ugalde

    2008-01-01

    Full Text Available This article addresses the difference between the concepts of governability and governance in economics and political science. The main focus is to address basic principles of neoclassical theory in order to explore alternative research approaches for the analysis of governance in institutional building and agent relationships to rules. With this purpose, the article assesses the adequacy of explanations of citizens decision making in democracies with sharp inequalities and heterogeneous preferences.

  1. Forschungszentrum Rossendorf, Institute for Safety Research. Annual report 1995

    International Nuclear Information System (INIS)

    Weiss, F.P.; Rindelhardt, U.

    1996-09-01

    The scientific work of the Institute of Safety Research covers a wide range of safety related investigations. During 1995 important results on thermo-fluid dynamic single effects, thermalhydraulics and neutron kinetics for accident analysis, materials safety, simulation of radiation and particle transport, mechanical integrity of technical systems and process monitoring, risk management for waste deposits, magneto-hydrodynamics of conductive fluids, and of renewable energies were reached. The annual report presents also lists of publications, conference contributions, meetings, and workshops. (DG)

  2. Institutional Infrastructure for Broader Impacts Engagement - Showcasing Effective Strategies and Approaches from a Large Research Institute

    Science.gov (United States)

    Gold, A. U.; Sullivan, S. B.; Smith, L. K.; Lynds, S. E.

    2014-12-01

    The need for robust scientific and especially climate literacy is increasing. Funding agencies mandate that scientists make their findings and data publically available. Ideally, this mandate is achieved by scientists and educators working together to translate research findings into common knowledge. The Cooperative Institute for Research in Environmental Sciences (CIRES) is the largest research institute at the University of Colorado and home institute to over 500 scientists. CIRES provides an effective organizational infrastructure to support its scientists in broadening their research impact. Education specialists provide the necessary experience, connections, logistical support, and evaluation expertise to develop and conduct impactful education and outreach efforts. Outreach efforts are tailored to the project needs and the scientists' interests. They span from deep engagement efforts with a high time commitment by the scientist thus a high dosage to short presentations by the scientists that reach many people without stimulating a deep engagement and have therefore a low dosage. We use three examples of current successful programs to showcase these different engagement levels and report on their impact: i) deep transformative and time-intensive engagement through a Research Experience for Community College students program, ii) direct engagement during a teacher professional development workshop centered around a newly developed curriculum bringing authentic climate data into secondary classrooms, iii) short-time engagement through a virtual panel discussion about the state of recent climate science topics, the recordings of which were repurposed in a Massive Open Online Course (MOOC). In this presentation, we discuss the challenges and opportunities of broader impacts work. We discuss successful strategies that we developed, stress the importance of robust impact evaluation, and summarize different avenues of funding outreach efforts.

  3. Creating an institutional resource for research education and career development: a novel model from Oregon Clinical and Translational Research Institute.

    Science.gov (United States)

    Morris, Cynthia D; McCracken, Karen; Samuels, Mary; Orwoll, Eric

    2014-06-01

    We have created an education and career development program within the CTSA structure at OHSU that serves the entire institution. We believe that this is unusual in scope among CTSA programs and has contributed to an increase in career development funding and research skills among fellows and faculty. While the key element is the institutional scope, important elements include: Tailoring programs of emphasis to points of inflection on the career pathway. Minimizing barriers to education by creating a flexible, tuition-free program. An integrated one-stop education and career development approach. An institutional program for career development award applicants as well as recipients. This career development program was developed within the context of a midsize health science university but the overall strategy may be applied to other CTSAs to simplify and reduce costs of education program development.

  4. 30 years of Central Institute for Nuclear Research at Rossendorf

    International Nuclear Information System (INIS)

    Scheler, W.; Flach, G.; Hennig, K.; Collatz, S.; Muenze, R.; Baldeweg, F.

    1986-10-01

    A celebration and a scientific colloquium dedicated the 30th anniversary of the foundation of the Central Institute for Nuclear Research (CINR) of the GDR Academy of Sciences were held on January, 23rd and 24th, '86 at Rossendorf. The speaches and lectures given by the president of the GDR Academy of Sciences and by scientists of the CINR dealt with problems of policy of science, history of the CINR, nuclear methods, microelectronics, nuclear energy research, development and production of radioisotopes and scientific instruments. (author)

  5. Computer Science Research Institute 2003 annual report of activities.

    Energy Technology Data Exchange (ETDEWEB)

    DeLap, Barbara J.; Womble, David Eugene; Ceballos, Deanna Rose

    2006-03-01

    This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2003 to December 31, 2003. During this period the CSRI hosted 164 visitors representing 78 universities, companies and laboratories. Of these 78 were summer students or faculty members. The CSRI partially sponsored 5 workshops and also organized and was the primary host for 3 workshops. These 3 CSRI sponsored workshops had 178 participants--137 from universities, companies and laboratories, and 41 from Sandia. Finally, the CSRI sponsored 18 long-term collaborative research projects and 5 Sabbaticals.

  6. Computer Science Research Institute 2004 annual report of activities.

    Energy Technology Data Exchange (ETDEWEB)

    DeLap, Barbara J.; Womble, David Eugene; Ceballos, Deanna Rose

    2006-03-01

    This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2004 to December 31, 2004. During this period the CSRI hosted 166 visitors representing 81 universities, companies and laboratories. Of these 65 were summer students or faculty. The CSRI partially sponsored 2 workshops and also organized and was the primary host for 4 workshops. These 4 CSRI sponsored workshops had 140 participants--74 from universities, companies and laboratories, and 66 from Sandia. Finally, the CSRI sponsored 14 long-term collaborative research projects and 5 Sabbaticals.

  7. Computer Science Research Institute 2005 annual report of activities.

    Energy Technology Data Exchange (ETDEWEB)

    Watts, Bernadette M.; Collis, Samuel Scott; Ceballos, Deanna Rose; Womble, David Eugene

    2008-04-01

    This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2005 to December 31, 2005. During this period, the CSRI hosted 182 visitors representing 83 universities, companies and laboratories. Of these, 60 were summer students or faculty. The CSRI partially sponsored 2 workshops and also organized and was the primary host for 3 workshops. These 3 CSRI sponsored workshops had 105 participants, 78 from universities, companies and laboratories, and 27 from Sandia. Finally, the CSRI sponsored 12 long-term collaborative research projects and 3 Sabbaticals.

  8. Interinstitutional variation in management decisions for treatment of 4 common types of cancer: A multi-institutional cohort study.

    Science.gov (United States)

    Weeks, Jane C; Uno, Hajime; Taback, Nathan; Ting, Gladys; Cronin, Angel; D'Amico, Thomas A; Friedberg, Jonathan W; Schrag, Deborah

    2014-07-01

    When clinical practice is governed by evidence-based guidelines and there is consensus about their validity, practice variation should be minimal. For areas in which evidence gaps exist, greater variation is expected. To systematically assess interinstitutional variation in management decisions for 4 common types of cancer. Multi-institutional, observational cohort study of patients with cancer diagnosed between July 2006 through May 2011 and observed through 31 December 2011. 18 cancer centers participating in the formulation of treatment guidelines and systematic outcomes assessment through the National Comprehensive Cancer Network. 25 589 patients with incident breast cancer, colorectal cancer, lung cancer, or non-Hodgkin lymphoma. Interinstitutional variation for 171 binary management decisions with varying levels of supporting evidence. For each decision, variation was characterized by the median absolute deviation of the center-specific proportions. Interinstitutional variation was high (median absolute deviation >10%) for 35 of 171 (20%) oncology management decisions, including 9 of 22 (41%) decisions for non-Hodgkin lymphoma, 16 of 76 (21%) for breast cancer, 7 of 47 (15%) for lung cancer, and 3 of 26 (12%) for colorectal cancer. Forty-six percent of high-variance decisions involved imaging or diagnostic procedures and 37% involved choice of chemotherapy regimen. The evidence grade underpinning the 35 high-variance decisions was category 1 for 0%, 2A for 49%, and 2B/other for 51%. Physician identifiers were unavailable, and results may not generalize outside of major cancer centers. The substantial variation in institutional practice manifest among cancer centers reveals a lack of consensus about optimal management for common clinical scenarios. For clinicians, awareness of management decisions with high variation should prompt attention to patient preferences. For health systems, high variation can be used to prioritize comparative effectiveness research

  9. Population-based geographic access to parent and satellite National Cancer Institute Cancer Center Facilities.

    Science.gov (United States)

    Onega, Tracy; Alford-Teaster, Jennifer; Wang, Fahui

    2017-09-01

    Satellite facilities of National Cancer Institute (NCI) cancer centers have expanded their regional footprints. This study characterized geographic access to parent and satellite NCI cancer center facilities nationally overall and by sociodemographics. Parent and satellite NCI cancer center facilities, which were geocoded in ArcGIS, were ascertained. Travel times from every census tract in the continental United States and Hawaii to the nearest parent and satellite facilities were calculated. Census-based population attributes were used to characterize measures of geographic access for sociodemographic groups. From the 62 NCI cancer centers providing clinical care in 2014, 76 unique parent locations and 211 satellite locations were mapped. The overall proportion of the population within 60 minutes of a facility was 22% for parent facilities and 32.7% for satellite facilities. When satellites were included for potential access, the proportion of some racial groups for which a satellite was the closest NCI cancer center facility increased notably (Native Americans, 22.6% with parent facilities and 39.7% with satellite facilities; whites, 34.8% with parent facilities and 50.3% with satellite facilities; and Asians, 40.0% with parent facilities and 54.0% with satellite facilities), with less marked increases for Hispanic and black populations. Rural populations of all categories had dramatically low proportions living within 60 minutes of an NCI cancer center facility of any type (1.0%-6.6%). Approximately 14% of the population (n = 43,033,310) lived more than 180 minutes from a parent or satellite facility, and most of these individuals were Native Americans and/or rural residents (37% of Native Americans and 41.7% of isolated rural residents). Racial/ethnic and rural populations showed markedly improved geographic access to NCI cancer center care when satellite facilities were included. Cancer 2017;123:3305-11. © 2017 American Cancer Society. © 2017 American

  10. Termination of past nuclear activities at the nuclear research institute

    International Nuclear Information System (INIS)

    Janzekovic, H.; Krizman, M.

    2006-01-01

    Many countries, particularly in Europe, started with nuclear programs in the fifties of the last century. As a consequence nuclear research institutes were established, among them also the Institute Jozef Stefan (IJS) in Slovenia. The nuclear activities at the IJS were related to the development of uranium ore processing technology and technologies comprising uranium oxide and hexafluoride. After very intensive period of nuclear activities the decline began step by step due to different reasons. Various approaches of the termination and decommissioning of facilities were used. The inspectors of the Slovenian Nuclear Safety Administration (SNSA), the responsible authority, started intensive activities at the IJS at the end of 2004. All together 22 research laboratories or research units were included in the inspection program and around 50 researchers of the IJS were involved into the inspection procedures. The inspection was very intensive in the laboratories and storages where past nuclear activities took place and were later on abandoned. As a result several contaminated equipments and sites in addition to around 200 unregistered sources were found. The majority of these sources is related to past nuclear activities. The inspection program related to the terminated research activities is still in progress. The IJS immediately started with the remediation activities including the development of methodology related to decontamination of radioactive liquids. The decontamination of two nuclear laboratories and three different storages of radioactive waste at its sites is in progress. Sixty of the above mentioned sources have been already stored in the Central Interim Storage for Radioactive Waste. (author)

  11. Annual report 1978. From the Research Institute of Physics, Stockholm

    International Nuclear Information System (INIS)

    Nilsson, A.

    1978-01-01

    This report covers the activities in 1978 at the Research Institute of Physics, Stockholm, Sweden. During this year the construction work on the caves for nuclear physics research in the new experimental hall has been completed. The cyclotron has been started up again after a shut-down of about 15 months. A new mini-computer system has been bought and installed at the institute which will be used for on-line data aquisition as well as for off-line computations and analysis. The experimental nuclear physics program has naturally been hampered by the shut-down of the cyclotron. During the main part of the year, experiments with participation of nuclear physicists from the institute have been carried out at laboratories in Uppsala, Aabo, Risoe, Darmstadt and Orsay. The collaboration with the CERN group studying exotic atoms has continued. The activities of the group working in the field of atomic physics at the 400kV accelerator show a clear trend towards the studies of reaction phenomena occuring in collisions of ions with solids and gases. The construction of the new high-power electron accelerator for research in time-resolved precision spectroscopy of atoms and molecules has been completed. The fusion-related experimental program of the surface physics group has continued with an emphasis on the work done in collaboration with the Institut fur Plasmaphysik, KFA, Julich. In order to be able to perform in situ sputtering and thin film migration studies, a new ultra-high-vacuum chamber is being connected simultaneously to the new 100V-10kV low-energy accelerator and the 2MV Van de Graaff accelerator. (E.R.)

  12. Enhancing research capacity of African institutions through social networking.

    Science.gov (United States)

    Jimenez-Castellanos, Ana; Ramirez-Robles, Maximo; Shousha, Amany; Bagayoko, Cheick Oumar; Perrin, Caroline; Zolfo, Maria; Cuzin, Asa; Roland, Alima; Aryeetey, Richmond; Maojo, Victor

    2013-01-01

    Traditionally, participation of African researchers in top Biomedical Informatics (BMI) scientific journals and conferences has been scarce. Looking beyond these numbers, an educational goal should be to improve overall research and, therefore, to increase the number of scientists/authors able to produce and publish high quality research. In such scenario, we are carrying out various efforts to expand the capacities of various institutions located at four African countries - Egypt, Ghana, Cameroon and Mali - in the framework of a European Commission-funded project, AFRICA BUILD. This project is currently carrying out activities such as e-learning, collaborative development of informatics tools, mobility of researchers, various pilot projects, and others. Our main objective is to create a self-sustained South-South network of BMI developers.

  13. Researching the experience of kidney cancer patients.

    Science.gov (United States)

    Taylor, K

    2002-09-01

    The author's personal experience as a kidney cancer patient, researcher and founder of a kidney cancer support group forms the basis for consideration of the challenges involved in researching patients' experiences. The researcher needs to understand the variability of those experiences in both clinical and psychological-emotional terms, and in relation to the personal, familial and social contexts of the patient. It is also essential to define the purpose of the research and to show how an understanding of personal experiences of cancer can be used to enhance the quality of care for cancer patients. The research encounter with a patient is also in some respects a therapeutic encounter requiring a considerable degree of sensitivity on the part of the researcher. The person-centred approach of Carl Rogers is of value in supporting such an encounter.

  14. Research Networking Systems: The State of Adoption at Institutions Aiming to Augment Translational Research Infrastructure

    Science.gov (United States)

    Obeid, Jihad S; Johnson, Layne M; Stallings, Sarah; Eichmann, David

    2015-01-01

    Fostering collaborations across multiple disciplines within and across institutional boundaries is becoming increasingly important with the growing emphasis on translational research. As a result, Research Networking Systems that facilitate discovery of potential collaborators have received significant attention by institutions aiming to augment their research infrastructure. We have conducted a survey to assess the state of adoption of these new tools at the Clinical and Translational Science Award (CTSA) funded institutions. Survey results demonstrate that most CTSA funded institutions have either already adopted or were planning to adopt one of several available research networking systems. Moreover a good number of these institutions have exposed or plan to expose the data on research expertise using linked open data, an established approach to semantic web services. Preliminary exploration of these publically-available data shows promising utility in assessing cross-institutional collaborations. Further adoption of these technologies and analysis of the data are needed, however, before their impact on cross-institutional collaboration in research can be appreciated and measured. PMID:26491707

  15. Modeling a description logic vocabulary for cancer research.

    Science.gov (United States)

    Hartel, Frank W; de Coronado, Sherri; Dionne, Robert; Fragoso, Gilberto; Golbeck, Jennifer

    2005-04-01

    The National Cancer Institute has developed the NCI Thesaurus, a biomedical vocabulary for cancer research, covering terminology across a wide range of cancer research domains. A major design goal of the NCI Thesaurus is to facilitate translational research. We describe: the features of Ontylog, a description logic used to build NCI Thesaurus; our methodology for enhancing the terminology through collaboration between ontologists and domain experts, and for addressing certain real world challenges arising in modeling the Thesaurus; and finally, we describe the conversion of NCI Thesaurus from Ontylog into Web Ontology Language Lite. Ontylog has proven well suited for constructing big biomedical vocabularies. We have capitalized on the Ontylog constructs Kind and Role in the collaboration process described in this paper to facilitate communication between ontologists and domain experts. The artifacts and processes developed by NCI for collaboration may be useful in other biomedical terminology development efforts.

  16. NCI Cancer Research Data Ecosystem

    Science.gov (United States)

    An infographic explaining NCI’s present and future efforts to promote a culture of sharing data—clinical, genomic, proteomic, imaging, patient histories, and outcomes data—among stakeholders to impact cancer care.

  17. Surge in Philanthropy Fuels Cancer Research.

    Science.gov (United States)

    2017-01-01

    Philanthropy could lead to faster cures by funding riskier research-projects more likely to fail but with potentially high impact-and promoting better teamwork among researchers. However, researchers and fundraisers say that it should augment, not replace, government funding. ©2017 American Association for Cancer Research.

  18. Activities of the Research Institute for Advanced Computer Science

    Science.gov (United States)

    Oliger, Joseph

    1994-01-01

    The Research Institute for Advanced Computer Science (RIACS) was established by the Universities Space Research Association (USRA) at the NASA Ames Research Center (ARC) on June 6, 1983. RIACS is privately operated by USRA, a consortium of universities with research programs in the aerospace sciences, under contract with NASA. The primary mission of RIACS is to provide research and expertise in computer science and scientific computing to support the scientific missions of NASA ARC. The research carried out at RIACS must change its emphasis from year to year in response to NASA ARC's changing needs and technological opportunities. Research at RIACS is currently being done in the following areas: (1) parallel computing; (2) advanced methods for scientific computing; (3) high performance networks; and (4) learning systems. RIACS technical reports are usually preprints of manuscripts that have been submitted to research journals or conference proceedings. A list of these reports for the period January 1, 1994 through December 31, 1994 is in the Reports and Abstracts section of this report.

  19. Collaborating to Move Research Forward: Proceedings of the 10th Annual Bladder Cancer Think Tank

    OpenAIRE

    Kamat, Ashish M.; Agarwal, Piyush; Bivalacqua, Trinity; Chisolm, Stephanie; Daneshmand, Sia; Doroshow, James H.; Efstathiou, Jason A.; Galsky, Matthew; Iyer, Gopa; Kassouf, Wassim; Shah, Jay; Taylor, John; Williams, Stephen B.; Quale, Diane Zipursky; Rosenberg, Jonathan E.

    2016-01-01

    The 10th Annual Bladder Cancer Think Tank was hosted by the Bladder Cancer Advocacy Network and brought together a multidisciplinary group of clinicians, researchers, representatives and Industry to advance bladder cancer research efforts. Think Tank expert panels, group discussions, and networking opportunities helped generate ideas and strengthen collaborations between researchers and physicians across disciplines and between institutions. Interactive panel discussions addressed a variety o...

  20. Knowledge management initiatives at the Philippine Nuclear Research Institute

    International Nuclear Information System (INIS)

    Bernido, C.C.; Conjares, A.E.L.; Halnin, C.G.; Anden, A.B.

    2006-01-01

    The Philippine Nuclear Research Institute (PNRI), with assistance from the IAEA, is in the process of setting up an integrated management system (IMS) for the whole Institute, following the guidelines published by the IAEA). The strategy for setting up a knowledge management system at the PNRI involves making knowledge management an integral part of the IMS, and the establishment of the PNRI intranet as a medium for discussions and sharing of knowledge. With its limited budget, the PNRI intranet was developed using open sources (Linux based). Also part of the knowledge management activities of the PNRI is its participation in regional networks which aim to preserve and share nuclear knowledge, such as the Asian Nuclear Safety Network (ANSN) and the Asian Network for Education in Nuclear Technology (ANENT), and its participation in National Government initiatives such as the Philippine eLib project and the ScINET-PHIL. (author)

  1. The emergency organization of the Federal Institute for Reactor Research

    International Nuclear Information System (INIS)

    Brunner, H.; Huerlimann, T.

    1977-01-01

    The organization and means of the emergency organization of the Federal Institute for Reactor Research (EIR), the eldest and largest nuclear installation in Switzerland, are described. It consists of a central command group and the following emergency teams: fire brigade, radiation protection, first aid, control, operating teams (reactors, hot laboratory etc.). The radiation protection team is formed by the Health Physics Division and is discussed in detail. A description of the alarm system and the first actions to be taken in case of an emergency is given. The importance of frequent and well-planned exercises and of radio communication between the teams and the command group is stressed and the emergency training programme of the EIR School for Radiation Protection, operated by the Health Physics Division, is presented. A fortunate lack of incidents at EIR is partly compensated for by experience gained from emergency team assistance operations during incidents outside the Institute. (author)

  2. NATO Advanced Research Institute on Search Theory and Applications

    CERN Document Server

    Stone, Lawrence

    1980-01-01

    The NATO Advanced Research Institute on Search Theory and Appli­ cations was held at the Hotel Algarve in Praia Da Rocha, Portugal, from March 26 through March 30, 1979, and was sponsored by the NATO Special Programme Panel on Systems Science. There were forty-one participants representing a wide range of backgrounds and interests. The purpose of the institute was to bring together people working in search theory and applications with potential users of search techniques to stimulate the increased application of recent­ ly developed search technology to civilian problems such as search and rescue, mineral exploration, surveillance, and fishing. Con­ versely, it was felt that by exposing search analysts to potential applications and new problems, they would be stimulated to develop new techniques for these applications and problems. The exchange of ideas and problems necessary to accomplish these goals was provided in the meeting workshops. There were three workshops, Search and Rescue, Exploration, and Sur...

  3. Iowa State Mining and Mineral Resources Research Institute

    Energy Technology Data Exchange (ETDEWEB)

    1990-08-01

    This final report describes the activities of the Iowa State Mining and Mineral Resources Research Institute (ISMMRRI) at Iowa State University for the period July 1, 1989, to June 30, 1990. Activities include research in mining- and mineral-related areas, education and training of scientists and engineers in these fields, administration of the Institute, and cooperative interactions with industry, government agencies, and other research centers. During this period, ISMMRRI has supported research efforts to: (1) Investigate methods of leaching zinc from sphalerite-containing ores. (2) Study the geochemistry and geology of an Archean gold deposit and of a gold-telluride deposit. (3) Enchance how-quality aggregates for use in construction. (4) Pre-clean coal by triboelectric charging in a fluidized-bed. (5) Characterize the crystal/grain alignment during processing of yttrium-barium-copper-perovskite (1-2-3) superconductors. (5) Study the fluid inclusion properties of a fluorite district. (6) Study the impacts of surface mining on community planning. (7) Assess the hydrophobicity of coal and pyrite for beneficiation. (8) Investigate the use of photoacoustic absorption spectroscopy for monitoring unburnt carbon in the exhaust gas from coal-fired boilers. The education and training program continued within the interdepartmental graduate minor in mineral resources includes courses in such areas as mining methods, mineral processing, industrial minerals, extractive metallurgy, coal science and technology, and reclamation of mined land. In addition, ISMMRRI hosted the 3rd International Conference on Processing and Utilization of High-Sulfur Coals in Ames, Iowa. The Institute continues to interact with industry in order to foster increased cooperation between academia and the mining and mineral community.

  4. Performance Engineering Research Institute SciDAC-2 Enabling Technologies Institute Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Lucas, Robert

    2013-04-20

    Enhancing the performance of SciDAC applications on petascale systems had high priority within DOE SC at the start of the second phase of the SciDAC program, SciDAC-2, as it continues to do so today. Achieving expected levels of performance on high-end computing (HEC) systems is growing ever more challenging due to enormous scale, increasing architectural complexity, and increasing application complexity. To address these challenges, the University of Southern California?s Information Sciences Institute organized the Performance Engineering Research Institute (PERI). PERI implemented a unified, tripartite research plan encompassing: (1) performance modeling and prediction; (2) automatic performance tuning; and (3) performance engineering of high profile applications. Within PERI, USC?s primary research activity was automatic tuning (autotuning) of scientific software. This activity was spurred by the strong user preference for automatic tools and was based on previous successful activities such as ATLAS, which automatically tuned components of the LAPACK linear algebra library, and other recent work on autotuning domain-specific libraries. Our other major component was application engagement, to which we devoted approximately 30% of our effort to work directly with SciDAC-2 applications. This report is a summary of the overall results of the USC PERI effort.

  5. 78 FR 107 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2013-01-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... evaluate grant applications. Place: National Human Genome Research Institute, 3rd Floor Conference Room....D., Scientific Review Officer, Scientific Review Branch, National Human Genome Research Institute...

  6. 76 FR 29772 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... clearly unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research... of Scientific Review, National Human Genome Research Institute, National Institutes of Health...

  7. 77 FR 5035 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... clearly unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research... Officer, Scientific Review Branch, National Human Genome Research Institute, National Institutes of Health...

  8. 77 FR 28888 - National Human Genome Research Institute Notice of Closed Meeting

    Science.gov (United States)

    2012-05-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research Institute Initial...: To review and evaluate grant applications. Place: National Human Genome Research Institute, 3635...

  9. 76 FR 28056 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-05-13

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Counselors, National Human Genome Research Institute. The meeting will be closed to the public as indicated... National Human Genome Research Institute, including consideration of personnel qualifications and...

  10. 76 FR 58023 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-09-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research Institute Initial..., Scientific Review Officer, Office of Scientific Review, National Human Genome Research Institute, National...

  11. 78 FR 64222 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-10-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... clearly unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research... Review, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, 301...

  12. 76 FR 17930 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-03-31

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research Institute Special... Review Officer, Scientific Review Branch, National Human Genome Research Institute, 5635 Fishers Lane...

  13. 76 FR 5390 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-01-31

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... unwarranted invasion of personal privacy. Place: National Human Genome Research Institute Special Emphasis... Officer, Scientific Review Branch, National Human Genome Research Institute, 5635 Fishers Lane, Suite 4076...

  14. 78 FR 70063 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2013-11-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Counselors, National Human Genome Research Institute. The meeting will be closed to the public as indicated... NATIONAL HUMAN GENOME RESEARCH INSTITUTE, including consideration of personnel qualifications and...

  15. 75 FR 13558 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-03-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Counselors, National Human Genome Research Institute. The meeting will be closed to the public as indicated... National Human Genome Research Institute, including consideration of personnel qualifications and...

  16. Using Large Institutional or National Databases to Evaluate Prostate Cancer Outcomes and Patterns of Care: Possibilities and Limitations

    Directory of Open Access Journals (Sweden)

    Daniel Su

    2011-01-01

    Full Text Available Prostate cancer is the most common non–skin-related cancer in men. With advances in technology, the care and treatment for men with this disease continues to become more complex. Large databases offer researchers a unique opportunity to conduct prostate cancer research in various areas, and provide important information that helps patients and providers determine prognosis after treatment. Furthermore, the studies using these databases may provide information on how side effects from various treatments can affect one's quality of life. Finally, information from these datasets can help to identify factors that determine why patients receive the treatments they do. Despite this, these databases are not without limitations. In this review, we discuss various available, national, multicenter, and institutional databases in the context of prostate cancer research, citing numerous important studies that have impacted on our understanding of prostate cancer outcomes.

  17. Behavioral Research in Cancer Prevention and Control

    Science.gov (United States)

    Klein, William M. P.; Bloch, Michele; Hesse, Bradford W.; McDonald, Paige G.; Nebeling, Linda; O’Connell, Mary E.; Riley, William T.; Taplin, Stephen H.; Tesauro, Gina

    2013-01-01

    Human behavior is central to the etiology and management of cancer outcomes and presents several avenues for targeted and sustained intervention. Psychosocial experiences such as stress and health behaviors including tobacco use, sun exposure, poor diet, and a sedentary lifestyle increase the risk of some cancers yet are often quite resistant to change. Cancer screening and other health services are misunderstood and over-utilized, and vaccination underutilized, in part because of the avalanche of information about cancer prevention. Coordination of cancer care is suboptimal, and only a small fraction of cancer patients enroll in clinical trials essential to the development of new cancer treatments. A growing population of cancer survivors has necessitated a fresh view of cancer as a chronic rather than acute disease. Fortunately, behavioral research can address a wide variety of key processes and outcomes across the cancer controbiol continuum from prevention to end-of-life care. Here we consider effects at the biobehavioral and psychological, social and organizational, and environmental levels. We challenge the research community to address key behavioral targets across all levels of influence, while taking into account the many new methodological tools that can facilitate this important work. PMID:24512871

  18. Databases and QSAR for Cancer Research

    Directory of Open Access Journals (Sweden)

    Adeel Malik

    2006-01-01

    Full Text Available In this review, we take a survey of bioinformatics databases and quantitative structure-activity relationship studies reported in published literature. Databases from the most general to special cancer-related ones have been included. Most commonly used methods of structure-based analysis of molecules have been reviewed, along with some case studies where they have been used in cancer research. This article is expected to be of use for general bioinformatics researchers interested in cancer and will also provide an update to those who have been actively pursuing this field of research.

  19. [Hospital biomedical research through the satisfaction of a Health Research Institute professionals].

    Science.gov (United States)

    Olmedo, C; Plá, R; Bellón, J M; Bardinet, T; Buño, I; Bañares, R

    2015-01-01

    A Health Research Institute is a powerful strategic commitment to promote biomedical research in hospitals. To assess user satisfaction is an essential quality requirement. The aim of this study is to evaluate the professional satisfaction in a Health Research Institute, a hospital biomedical research centre par excellence. Observational study was conducted using a satisfaction questionnaire on Health Research Institute researchers. The explored dimensions were derived from the services offered by the Institute to researchers, and are structured around 4 axes of a five-year Strategic Plan. A descriptive and analytical study was performed depending on adjustment variables. Internal consistency was also calculated. The questionnaire was completed by 108 researchers (15% response). The most valued strategic aspect was the structuring Areas and Research Groups and political communication and dissemination. The overall rating was 7.25 out of 10. Suggestions for improvement refer to the need for help in recruitment, and research infrastructures. High internal consistency was found in the questionnaire (Cronbach alpha of 0.9). So far research policies in health and biomedical environment have not been sufficiently evaluated by professionals in our field. Systematic evaluations of satisfaction and expectations of key stakeholders is an essential tool for analysis, participation in continuous improvement and advancing excellence in health research. Copyright © 2015 SECA. Published by Elsevier Espana. All rights reserved.

  20. Norwegian Institute for Air Research Annual Report 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    The foundation Norwegian Institute for Air Research (NILU) conducts research and assessment of technical, economic, hygienic and other environmental issues related to air pollution and cleaning of polluted air. NILU serves the national market for research and development within the field of air pollution. The main purpose of the subsidiary company NILU Products Ltd., established in 1996, is to manage the strategic owner interests of the parent company as well as market products and systems developed by NILU. Among the projects in which NILU participated in 2001 are a number of EU projects under the fifth framework programme. The main topics with NILU participation are related to ozone layer- and ultraviolet changes, pollution and climate change, satellite validation, changes in atmospheric chemistry, particulate matter in air, discharges from aircraft, regional and global dispersion of environmental toxins, standardization and monitoring methods, electronic distribution of environmental data and environmental influence on building materials.

  1. Annual report of Nuclear Science Research Institute, JFY 2012

    International Nuclear Information System (INIS)

    2014-03-01

    Nuclear Science Research Institute (NSRI) is composed of Planning and Coordination Office, Fukushima Project Team and six departments, namely Department of Operational Safety Administration, Department of Radiation Protection, Engineering Services Department, Department of Research Reactor and Tandem Accelerator, Department of Fukushima Technology Development and Department of Decommissioning and Waste Management. This annual report of JFY 2012 summarizes the activities of NSRI, the activities of the R and D Directorates and Human Resources Development at NSRI site, and is expected to be referred and utilized by R and D departments and project promotion sectors at NSRI site for the enhancement of their own research and management activities to attain their goals according to “Middle-term Plan” successfully and effectively. (author)

  2. Toward ethical norms and institutions for climate engineering research

    International Nuclear Information System (INIS)

    Morrow, David R; Kopp, Robert E; Oppenheimer, Michael

    2009-01-01

    Climate engineering (CE), the intentional modification of the climate in order to reduce the effects of increasing greenhouse gas concentrations, is sometimes touted as a potential response to climate change. Increasing interest in the topic has led to proposals for empirical tests of hypothesized CE techniques, which raise serious ethical concerns. We propose three ethical guidelines for CE researchers, derived from the ethics literature on research with human and animal subjects, applicable in the event that CE research progresses beyond computer modeling. The Principle of Respect requires that the scientific community secure the global public's consent, voiced through their governmental representatives, before beginning any empirical research. The Principle of Beneficence and Justice requires that researchers strive for a favorable risk-benefit ratio and a fair distribution of risks and anticipated benefits, all while protecting the basic rights of affected individuals. Finally, the Minimization Principle requires that researchers minimize the extent and intensity of each experiment by ensuring that no experiments last longer, cover a greater geographical extent, or have a greater impact on the climate, ecosystem, or human welfare than is necessary to test the specific hypotheses in question. Field experiments that might affect humans or ecosystems in significant ways should not proceed until a full discussion of the ethics of CE research occurs and appropriate institutions for regulating such experiments are established.

  3. Selective dissemination of information of library in scientific research institution

    International Nuclear Information System (INIS)

    Liu Wenping

    2010-01-01

    Selective Dissemination of Information (SDI) Service, which is an important component of intelligence, is the intelligence researcher to select key subjects and major issues and key technology or innovation goals under the actual needs of scientific research personnel issues, using network communication technology and database technology and information retrieval technologies, sustained and in a timely manner to track all kinds of literature for the front-line services, until the completion of research topics or key problem-solving. Library of China Institute of Atomic Energy is struggling to meet the diverse needs of customers, targeted to provide a lot of useful information for scientific researchers to use less time as possible to obtain as much intelligence information, and to research workers and leading to the successful completion of research tasks, and various decisions. The implementation of SDI services to identify clients and scope, to format SDI service team, to determine the SDI service principles and service mode. SDI services Selective demand intelligence researchers have been asked to improve their quality, to improve their interpersonal communication skills. (author)

  4. [Activities of Research Institute for Advanced Computer Science

    Science.gov (United States)

    Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

    2001-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administrations missions. RIACS is located at the NASA Ames Research Center, Moffett Field, California. RIACS research focuses on the three cornerstones of IT research necessary to meet the future challenges of NASA missions: 1. Automated Reasoning for Autonomous Systems Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth. 2. Human-Centered Computing Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities. 3. High Performance Computing and Networking Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to analysis of large scientific datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply IT research to a variety of NASA application domains. RIACS also engages in other activities, such as workshops, seminars, visiting scientist programs and student summer programs, designed to encourage and facilitate collaboration between the university and NASA IT research communities.

  5. Toward ethical norms and institutions for climate engineering research

    Science.gov (United States)

    Morrow, David R.; Kopp, Robert E.; Oppenheimer, Michael

    2009-10-01

    Climate engineering (CE), the intentional modification of the climate in order to reduce the effects of increasing greenhouse gas concentrations, is sometimes touted as a potential response to climate change. Increasing interest in the topic has led to proposals for empirical tests of hypothesized CE techniques, which raise serious ethical concerns. We propose three ethical guidelines for CE researchers, derived from the ethics literature on research with human and animal subjects, applicable in the event that CE research progresses beyond computer modeling. The Principle of Respect requires that the scientific community secure the global public's consent, voiced through their governmental representatives, before beginning any empirical research. The Principle of Beneficence and Justice requires that researchers strive for a favorable risk-benefit ratio and a fair distribution of risks and anticipated benefits, all while protecting the basic rights of affected individuals. Finally, the Minimization Principle requires that researchers minimize the extent and intensity of each experiment by ensuring that no experiments last longer, cover a greater geographical extent, or have a greater impact on the climate, ecosystem, or human welfare than is necessary to test the specific hypotheses in question. Field experiments that might affect humans or ecosystems in significant ways should not proceed until a full discussion of the ethics of CE research occurs and appropriate institutions for regulating such experiments are established.

  6. [Managing a health research institute: towards research excellence through continuous improvement].

    Science.gov (United States)

    Olmedo, Carmen; Buño, Ismael; Plá, Rosa; Lomba, Irene; Bardinet, Thierry; Bañares, Rafael

    2015-01-01

    Health research institutes are a strategic commitment considered the ideal environment to develop excellence in translational research. Achieving quality research requires not only a powerful scientific and research structure but also the quality and integrity of management systems that support it. The essential instruments in our institution were solid strategic planning integrated into and consistent with the system of quality management, systematic evaluation through periodic indicators, measurement of key user satisfaction and internal audits, and implementation of an innovative information management tool. The implemented management tools have provided a strategic thrust to our institute while ensuring a level of quality and efficiency in the development and management of research that allows progress towards excellence in biomedical research. Copyright © 2015 SESPAS. Published by Elsevier Espana. All rights reserved.

  7. Researchers studying alternative to bladder removal for bladder cancer patients | Center for Cancer Research

    Science.gov (United States)

    A new phase I clinical trial conducted by researchers at the Center for Cancer Research (CCR) is evaluating the safety and tolerability, or the degree to which any side effects can be tolerated by patients, of a two-drug combination as a potential alternative to bladder removal for bladder cancer patients. The trial targets patients with non-muscle invasive bladder cancer (NMIBC) whose cancers have stopped responding to traditional therapies. Read more...

  8. Malaysian researchers talk about the influence of culture on research misconduct in higher learning institutions.

    Science.gov (United States)

    Olesen, Angelina P; Amin, Latifah; Mahadi, Zurina

    2017-01-01

    Based on a previous survey by the Office of Research Integrity (ORI) in the USA, a considerable number of foreign research scientists have been found guilty of research misconduct. However, it remains unclear as to whether or not cultural factors really contribute to research misconduct. This study is based on a series of interviews with Malaysian researchers from the local universities regarding their own professional experiences involving working with researchers or research students from different countries or of different nationalities. Most of the researchers interviewed agreed that cultures do shape individual character, which influences the way that such individuals conduct research, their decision-making, and their style of academic writing. Our findings also showed that working culture within the institution also influences research practices, as well as faculty mentorship of the younger generation of researchers. Given the fact such misconduct might be due to a lack of understanding of research or working cultures or practices within the institution, the impact on the scientific community and on society could be destructive. Therefore, it is suggested that the institution has an important role to play in orienting foreign researchers through training, mentoring, and discussion with regard to the "does" and "don'ts" related to research, and to provide them with an awareness of the importance of ethics when it comes to conducting research.

  9. Anticancer patent landscape and technology assessment of Indian public-funded research institutes and organizations.

    Science.gov (United States)

    Dara, Ajay; Sangamwar, Abhay T

    2014-08-01

    This review discusses the various drug therapeutic targets and latest technologies of anticancer patents from 10 Indian public-funded research organizations covering more than 150 esteemed institutes. We have identified and reported the leading assignee and inventors along with their collaboration network and, thereby, have analyzed the various patent trends, geographical distributions, citation maps, Derwent World Patents Index, international patent classification analysis and the like. This article provides the insights of 1905 patent documents from 191 families and discusses in-depth anticancer technology through categorization studies at the level of drug discovery, drug development and treatment and diagnosis. In addition, various cancer targets were correlated with recent technologies so as to identify the white spaces for upcoming technologies. Over a period of 13 years (1990 - 2013) the main focus of Indian cancer research was in the field of synthetic chemistry and natural extracts followed by the pharmaceutical compositions and combinations, whereas, the white spaces for future cancer remedy were identified from research in the areas of cancer stem cell lines, vaccines, gene therapy, nano formulations with targeted drug delivery systems as core and latest technologies.

  10. NATO Advanced Research Institute on Health Services Systems

    CERN Document Server

    Werff, Albert; Hirsch, Gary; Barnard, Keith

    1984-01-01

    The Advanced Research Institute on "Health Services Systems" was held under the auspices of the NATO Special Programme Panel on Systems Science as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international cooperation. A special word is said in this respect supra by Pro­ fessor Checkland, Chairman of the Systems Science Panel. The Advanced Research Institute (ARI) was organized for the purpose of bringing together senior scientists to seek a consensus on the assessment of the present state of knowledge on the specific topic of "health services systems" and to present views and recom­ mendations for future health services research directions, which should be of value to both the scientific community and the people in charge of reorienting health services. The conference was structured so as to permit the assembly of a variety of complementary viewpoints through intensive group discussions to be the basis of this final report. Invitees were selected fr...

  11. Project INSPIRE-HBCU Undergraduate Collaborative Summer Training Program to Inspire Students in Prostate Cancer Research

    National Research Council Canada - National Science Library

    Kumar, Nagi

    2007-01-01

    ... sciences research for promising undergraduate students enrolled at Florida A & M University (FAMU), who are at an important career-decision-making point, in a host institution such as the Moffitt Cancer Center...

  12. Project INSPIRE-HBCU Undergraduate Collaborative Summer Training Program to Inspire Students in Prostate Cancer Research

    National Research Council Canada - National Science Library

    Kumar, Nagi

    2008-01-01

    ... sciences research for promising undergraduate students enrolled at Florida A & M University (FAMU), who are at an important career-decision-making point, in a host institution such as the Moffitt Cancer Center...

  13. Institutional repository for research projects : Case of a research project at Nihon University

    Science.gov (United States)

    Fujimori, Hiroki

    We have participated in the “eSciDoc project” of National Institute for Materials Science (NIMS), Japan and Max Planck Institute, Germany. We have begun to experiment using the eSciDoc as an institutional repository for research results of the “development of functional materials based on design and control of crystal and electronic structures” in College of Humanities and Sciences, Nihon University of the “Strategic Research Base Development” Program for Private Universities subsidized by Ministry of Education, Culture, Sports, Science and Technology (2009).

  14. Forschungszentrum Rossendorf, Institute of Safety Research. Annual report 1997

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, F.P.; Rindelhardt, U. [eds.

    1998-10-01

    The research work of the institute aims at the assessment and increase of the safety of technical facilities. Subject of the investigation are equally nuclear plants and installations of process industries. To analyse thermo-fluiddynamic phenomena of accident scenarios physical models and computer codes are developed as well for multi-phase and multi-component flows as for the time and space dependent power release (neutron kinetics in light water reactors, reaction kinetics of exothermic chemical reactions). Emphasis is put on the description of spatial flows and the transient evolution of flow patterns. (orig.)

  15. Institute of Biochemistry and Biophysics. Research Report 1996-1997

    International Nuclear Information System (INIS)

    1998-01-01

    Scientific interests of the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences have evolved from classical biochemistry, biophysics and physiological chemistry to up-to-date molecular biology. Research interests are focussed on replication, mutagenesis and repair of DNA; regulation of gene expression at various levels; biosynthesis and post-translational modifications of proteins; gene sequencing and functional analysis of open reading frames; structure, function and regulation of enzymes; conformation of proteins and peptides; modelling of structures and prediction of functions of proteins; mechanisms of electron transfer in polypeptides

  16. Nebraska Prostate Cancer Research Program

    Science.gov (United States)

    2014-07-01

    2010). Therapeutic Potential of Curcumin : Inhibition of MIC-1/GDF-15 Expression in Prostate Cancer Cells Exposed to Heavy Metal Carcinogen. UNMC...to monitor "What effect do Curcumin , NiCl2, and CoCl2 has on PC3M, LnCap, RWPE1, and PC3 cell lines." She plans on using the knowledge gained during...of Curcumin : Inhibition of MIC-1/GDF-15 Expression in Prostate Cancer Cells Exposed to Heavy Metal Carcinogen Brittany T. Jones, Poomy Pandey

  17. DCB - Cancer Immunology, Hematology, and Etiology Research

    Science.gov (United States)

    Part of NCI’s Division of Cancer Biology’s research portfolio, studies supported include the characterization of basic mechanisms relevant to anti-tumor immune responses and hematologic malignancies.

  18. NIH Research Leads to Cervical Cancer Vaccine

    Science.gov (United States)

    ... Transmitted Diseases NIH Research Leads to Cervical Cancer Vaccine Past Issues / Fall 2008 Table of Contents For ... Douglas Lowy (left) and John Schiller developed the vaccine to prevent HPV infection in women, the cause ...

  19. The HPV Vaccine | Center for Cancer Research

    Science.gov (United States)

    Two researchers leveraged CCR’s unique environment of investigator-driven inquiry to pursue studies of two cancer-causing genes that eventually led to the development of a vaccine against two forms of human papillomavirus.

  20. Barrett's Esophagus Translational Research Network (BETRNet) | Division of Cancer Prevention

    Science.gov (United States)

    The goal of BETRNet is to reduce the incidence, morbidity, and mortality of esophageal adenocarcinoma by answering key questions related to the progression of the disease, especially in the premalignant stage. In partnership with NCI’s Division of Cancer Biology, multidisciplinary translational research centers collaborate to better understand the biology of Barrett's esophagus and esophageal adenocarcinoma to improve risk stratification and develop prevention strategies. | Multi-disciplinary, multi-institutional collaboration to enhance understanding of Barrett's esophagus and to prevent esophageal adenocarcinoma.

  1. Research data management in academic institutions: A scoping review.

    Science.gov (United States)

    Perrier, Laure; Blondal, Erik; Ayala, A Patricia; Dearborn, Dylanne; Kenny, Tim; Lightfoot, David; Reka, Roger; Thuna, Mindy; Trimble, Leanne; MacDonald, Heather

    2017-01-01

    The purpose of this study is to describe the volume, topics, and methodological nature of the existing research literature on research data management in academic institutions. We conducted a scoping review by searching forty literature databases encompassing a broad range of disciplines from inception to April 2016. We included all study types and data extracted on study design, discipline, data collection tools, and phase of the research data lifecycle. We included 301 articles plus 10 companion reports after screening 13,002 titles and abstracts and 654 full-text articles. Most articles (85%) were published from 2010 onwards and conducted within the sciences (86%). More than three-quarters of the articles (78%) reported methods that included interviews, cross-sectional, or case studies. Most articles (68%) included the Giving Access to Data phase of the UK Data Archive Research Data Lifecycle that examines activities such as sharing data. When studies were grouped into five dominant groupings (Stakeholder, Data, Library, Tool/Device, and Publication), data quality emerged as an integral element. Most studies relied on self-reports (interviews, surveys) or accounts from an observer (case studies) and we found few studies that collected empirical evidence on activities amongst data producers, particularly those examining the impact of research data management interventions. As well, fewer studies examined research data management at the early phases of research projects. The quality of all research outputs needs attention, from the application of best practices in research data management studies, to data producers depositing data in repositories for long-term use.

  2. Research data management in academic institutions: A scoping review.

    Directory of Open Access Journals (Sweden)

    Laure Perrier

    Full Text Available The purpose of this study is to describe the volume, topics, and methodological nature of the existing research literature on research data management in academic institutions.We conducted a scoping review by searching forty literature databases encompassing a broad range of disciplines from inception to April 2016. We included all study types and data extracted on study design, discipline, data collection tools, and phase of the research data lifecycle.We included 301 articles plus 10 companion reports after screening 13,002 titles and abstracts and 654 full-text articles. Most articles (85% were published from 2010 onwards and conducted within the sciences (86%. More than three-quarters of the articles (78% reported methods that included interviews, cross-sectional, or case studies. Most articles (68% included the Giving Access to Data phase of the UK Data Archive Research Data Lifecycle that examines activities such as sharing data. When studies were grouped into five dominant groupings (Stakeholder, Data, Library, Tool/Device, and Publication, data quality emerged as an integral element.Most studies relied on self-reports (interviews, surveys or accounts from an observer (case studies and we found few studies that collected empirical evidence on activities amongst data producers, particularly those examining the impact of research data management interventions. As well, fewer studies examined research data management at the early phases of research projects. The quality of all research outputs needs attention, from the application of best practices in research data management studies, to data producers depositing data in repositories for long-term use.

  3. CCR Interns | Center for Cancer Research

    Science.gov (United States)

    The Cancer Research Interns (CRI) Summer Program was inaugurated in 2004 to increase the diversity of trainee applicants to the Center for Cancer Research (CCR). We have placed 339 students from 2004 to 2017, in labs and branches across the CCR. The Division provides the training dollars, some Service & Supply funds, and travel support for those students who meet the financial eligibility criteria (View and/or print the 2018 flier).

  4. Globus | Informatics Technology for Cancer Research (ITCR)

    Science.gov (United States)

    Globus software services provide secure cancer research data transfer, synchronization, and sharing in distributed environments at large scale. These services can be integrated into applications and research data gateways, leveraging Globus identity management, single sign-on, search, and authorization capabilities. Globus Genomics integrates Globus with the Galaxy genomics workflow engine and Amazon Web Services to enable cancer genomics analysis that can elastically scale compute resources with demand.

  5. 77 FR 38840 - Proposed Collection; Comment Request; National Institute of Nursing Research (NINR) Summer...

    Science.gov (United States)

    2012-06-29

    ... Request; National Institute of Nursing Research (NINR) Summer Genetics Institute Alumni Survey SUMMARY: In.../National Institute of Nursing Research (NINR) Summer Genetics Institute Alumni Survey. Type of Information... opportunity for public comment on proposed data collection projects, the National Institute of Nursing...

  6. Quality Research in Higher Education Institutions in Oman: Some Views of Teacher Researchers

    Directory of Open Access Journals (Sweden)

    Ahmed Ali Saleh Al Ajmi

    2015-06-01

    Full Text Available Academic research remains a prime source of knowledge and innovation for higher education institutions (HEIs that strive to grow, expand and develop their academic reputations and standards. Yet, research informs teaching practices, shapes social changes and it has financial outcomes for HEIs. Therefore, it is imperative to develop institutional policies and strategies for promoting and sustaining quality research in HEIs in Oman. There are a number of international frameworks and models which have been developed to measure research quality in HEIs around the world. For example, bibliometrics were used to assess research quality in HEIs in the UK because bibliometric data can provide a number of component variables. An appropriate bibliometric model may include components such as output volume, diversity of outputs, citation volume, journal impact factor and average citations per publication, etc. Moreover, other popular examples of models for assessing research quality are Multidimensional Research Assessment Matrix (MRAM used in Europe and the UK’s Research Assessment Exercise (RAE. However, neither of the above mentioned models is adopted by HEIs in Oman. Thus, the current study is an attempt to explore some institutional, international, logistic and pragmatic factors that impact academic research and publication quality, review popular international research quality assessment models and explore the possibility of applying them in the Omani context. To achieve the study objectives, 20 teacher researchers were surveyed and the findings and recommendations were presented. Keywords: Quality Research, HEIs in Oman, International Models, Factors, Teacher Researchers' Views

  7. Research Vessel HEINCKE Operated by the Alfred-Wegener-Institute

    Directory of Open Access Journals (Sweden)

    Rainer Knust

    2017-11-01

    Full Text Available HEINCKE operated by the Alfred-Wegener-Institut Helmholtz-Zentrum für Polar- und Meeresforschung, is a medium size multipurpose research vessel, which was designed for long-term cruises throughout the North Atlantic Sea up to Svalbard and the adjacent shelf seas. She offers work places and accommodation for 12 scientists and 12 crew members. The operating range of this low noise ship is about 7500 nautical miles (= 30 passage days. Four laboratories (wet, dry, constant temperature controlled and hydroacoustic/CTD offer almost vibration-free work places. Additionally space is available for special containers. The ship is equipped with several winch systems, cranes, and sonar systems, which allow a wide range of biological, chemical, oceanographic, geological and geophysical research applications. The onboard science support equipment allows working in water depths of up to approximately 2000 meters.

  8. International human cooperation in Japan Atomic Energy Research Institute

    International Nuclear Information System (INIS)

    Shiba, Koreyuki; Kaieda, Keisuke; Makuuchi, Keizo; Takada, Kazuo; Nomura, Masayuki

    1997-01-01

    Rearing of talented persons in the area of nuclear energy is one of the important works in Japan Atomic Energy Research Institute. In this report, the present situations and future schedules of international human cooperation in this area wsere summarized. First, the recent activities of International Nuclear Technology Center were outlined in respect of international human cooperation. A study and training course which was started in cooperation with JICA and IAEA from the middle of eighties and the international nuclear safety seminar aiming at advancing the nuclear safety level of the world are now being put into practice. In addition, a study and training for rearing talented persons was started from 1996 to improve the nuclear safety level of the neighbouring countries. The activities of the nuclear research interchange system by Science and Technology Agency established in 1985 and Bilateral Co-operation Agreement from 1984 were explained and also various difficulties in the international cooperation were pointed out. (M.N.)

  9. Forschungszentrum Rossendorf, Institute of Safety Research. Annual report 1996

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, F.P.; Rindelhardt, U. [eds.

    1997-08-01

    The research of the institute aims at the safety assessment of the design of nuclear and chemical facilities, the development of accident management procedures, and the increase of operational safety by improved plant surveillance. Physical models and computer codes are developed for multiphase/multicomponent flows and for the space and time dependent power release in nuclear and chemical reactors to be able to analyse the thermo-fluiddynamic phenomena during assumed accident scenarios. Emphasis is particulary focussed on spatial flow phenomena and the time dependent change of flow patterns. Sustainable void fraction probes and tomographic systems are developed to measure those parameters of two phase flows that characterize the exchange of pulse, energy and mass between the phases and components. The research related to materials safety is directed to the behaviour of components exposed to neutron and gamma radiation. The susceptibility to irradiation induced embrittlement and the behaviour of annealed material during reirradiation are investigated by fracture mechanical methods in dependence on the materials composition. The work on process and plant diagnostics makes available basic methods for early failure detection and operational monitoring which are important means of accident prevention. Recent initiatives of the institute are concerned with the transport of pollutants in the geosphere. Particularly, codes are developed for the simulation of physical and chemical processes during the transport of pollutants in unsaturated zones of the soil. (orig.)

  10. Forschungszentrum Rossendorf, Institute of Safety Research. Annual report 1996

    International Nuclear Information System (INIS)

    Weiss, F.P.; Rindelhardt, U.

    1997-08-01

    The research of the institute aims at the safety assessment of the design of nuclear and chemical facilities, the development of accident management procedures, and the increase of operational safety by improved plant surveillance. Physical models and computer codes are developed for multiphase/multicomponent flows and for the space and time dependent power release in nuclear and chemical reactors to be able to analyse the thermo-fluiddynamic phenomena during assumed accident scenarios. Emphasis is particularly focussed on spatial flow phenomena and the time dependent change of flow patterns. Sustainable void fraction probes and tomographic systems are developed to measure those parameters of two phase flows that characterize the exchange of pulse, energy and mass between the phases and components. The research related to materials safety is directed to the behaviour of components exposed to neutron and gamma radiation. The susceptibility to irradiation induced embrittlement and the behaviour of annealed material during reirradiation are investigated by fracture mechanical methods in dependence on the materials composition. The work on process and plant diagnostics makes available basic methods for early failure detection and operational monitoring which are important means of accident prevention. Recent initiatives of the institute are concerned with the transport of pollutants in the geosphere. Particularly, codes are developed for the simulation of physical and chemical processes during the transport of pollutants in unsaturated zones of the soil. (orig.)

  11. Tata Institute of Fundamental Research School of Physics

    International Nuclear Information System (INIS)

    Daniel, R.R.

    1975-01-01

    The diverse activities currently in progress in the School of Physics at Tata Institute of Fundamental Research, Bombay are reported in detail. The activities involving theoretical and experimental research are grouped under the following areas: (1) pure physics (2) astronomy and space science (3) chemical and biological studies and (4) applied research. In pure physics, studies are in progress in nuclear physics, high energy physics and solid state physics. In astronomy and space science, the fields of investigation comprise: cosmic ray physics, theoretical astrophysics and radio-astronomy. In chemical physics, structure of a variety of systems have been investigated using NMR and Moessbauer techniques. In molecular biology, basic biological processes have been studied in terms of structure and properties of biomolecules. In addition to these areas of pure research, considerable advances have been made in computer science and technology, solid state electronics, microwave engineering and hydrogy. The work done in each one of these areas is briefly summarized. A number of supporting research facilities are mentioned. A brief mention has also been made on the existing education and training programmes. (A.K.)

  12. Establishment of a National Ecological Research Program and Institute

    Energy Technology Data Exchange (ETDEWEB)

    Van Hook, R.I.

    1990-12-31

    Establishment of a national ecological research program and institute is discussed. The author says we need to establish a long-term ecological research program to develop a fuller understanding of basic ecosystem process so that scientists can evaluate the health of ecological systems and can predict quantitative and qualitative changes in these systems under foreseeable natural and man-made stress. This area is beginning to be addressed by the CEES, for example, but again with insufficient funding in comparison with other aspects of the US Global Change Program. The major elements of a long-term ecological research program should focus on providing support to develop the theories and hypotheses that dictate the required ecological measurements. EMAP is an excellent example of a large program that could benefit from new funding resources for the development of ecological theory and the study of ecological processes. These understandings are particularly important, and lacking, in system interfaces such as land/water interactions and atmosphere/canopy interactions. Funding stability for long-term ecological research can only be attained through a national commitment to the need. The commitment should be directed in a way that is sensitive to, but not controlled by, policy. Policy issues are particularly important as we attempt to deal with major environmental concerns, but long-term ecological research needs to be sufficiently independent of this process in order to maintain continuity and stability.

  13. CCR Interns | Center for Cancer Research

    Science.gov (United States)

    The Cancer Research Interns (CRI) Summer Program was inaugurated in 2004 to provide an open door for students looking for an initial training opportunity. The goal is to enhance diversity within the CCR (Center for Cancer Research) training program and we have placed 338 students from 2004 to 2017, in labs and branches across the division.  The CCR and the Center for Cancer Training’s Office of Training and Education provide stipend support, some Service & Supply funds, and travel support for those students who meet the financial eligibility criteria (

  14. Roswell Park Cancer Institute/Howard University Prostate Cancer Scholars Program

    Science.gov (United States)

    2017-10-01

    Prostate Cancer Scholars Program is designed to encourage students from under-represented minority groups to enter graduate training and ultimately...Howard University Prostate Cancer Scholars Program (RHPCS) aims to encourage students from under-represented minority groups to enter graduate training...developing healthcare and research professionals by feeding the pipeline of subsequent college science graduates poised to enter graduate training in the

  15. Cancer incidence and mortality in children in the Mexican Social Security Institute (1996-2013

    Directory of Open Access Journals (Sweden)

    Arturo Fajardo-Gutiérrez

    2016-03-01

    Full Text Available Objective. To identify the cancer incidence and mortality in Mexican Social Security Institute beneficiary (MSSI-B chil- dren during 1996-2013. Materials and methods. Both cancer cases (n=4 728 and deaths (n=2 378 were analyzed in MSSI-B children who were registered in five states of the Mexican Republic. The incidence and mortality trends and the incidences (rate x 1 000 000 children / year of the type of cancer, age, sex, and place of residence were obtained. Results. For both indicators (incidence and mortality, there was a downward trend for the period of 1996-2001 and a stable trend for 2002-2013. This occurred in the over- all mortality and incidence trends of the Estado de México and Chiapas and in the leukemia and the acute lymphoid subgroups. The annual overall incidence was 128 cases per 1 000 000 children. Leukemia, lymphomas, and central nervous system tumors were the principal cancer groups. Conclusions. Cancer mortality for the period of 2002-2013 did not diminish. Interinstitutional and/or international research should be designed to improve the care of these children.

  16. Dedicated researcher brings cancer care to rural communities

    Directory of Open Access Journals (Sweden)

    Sharan Bhuller

    2016-10-01

    Full Text Available As an ardent cancer researcher, Dr. Smita Asthana has a vision to create wider awareness on cancer and its prevention, and aims to work on translational research to benefit the general public through the implementation of evidence-based research. “I have been associated with the National Institute of Cancer Prevention and Research (NICPR and Institute of Cytology and Preventive Oncology (ICPO since November 2004 and have progressed over a period of time from being a staff scientist to the current role of a senior scientist,” says Dr. Asthana, who is presently with NICPR’s Biostatistics and Epidemiology division.“I have been working in various positions that deal with the design, execution, and evaluation of medical projects. Recently, we have concluded two major cervical cancer screening projects and conducted a screening of 10,000 women in rural areas,” she tells AMOR. One project, funded by the Indian Council of Medical Research, was carried out 100 km west of New Delhi in the rural town of Dadri “as part of an operational research to see the implementation of VIA (visual inspection with acetic acid and VILI (visual inspection with Lugol's iodine screenings with the help of existing healthcare infrastructure,” she explains.As a leading researcher in cervical cancer screening, she completed an Indo-US collaborative project on the clinical performance of a human papillomavirus (HPV test, used as a strategy for screening cervical cancer in rural communities, with funding from the Bill and Melinda Gates Foundation via the international non-profit global health organization PATH. “The primary objective of the project was to observe the performance of careHPV, a new diagnostic kit, in a rural setup,” she says.CareHPV is a highly sensitive DNA test, which detects 14 different types of the human papillomavirus that cause cervical cancer, providing results more rapidly than other DNA tests and is designed especially for use in clinics

  17. Alligator Rivers Region Research Institute: annual research summary 1989-1990

    International Nuclear Information System (INIS)

    1991-01-01

    The Alligator Rivers Region Research Institute (ARRRI) research activities are associated with an assessment of environmental effect of mining in the region. While emphasis on baseline research is now much reduced, some projects are still necessary because of significant changes in the Magela Creek system, because new areas of proposed mining have been identified (e.g. Coronation Hill) and because the emphasis now being placed on rehabilitation research requires a sound knowledge of the Region's flora. The ARRRI rehabilitation research program has concentrated on the Ranger mine site, principally because it is at a critical planning stage where detailed research information is required. With regard to the development of techniques, research at the Institute has led to the development of specific analytical methods or protocols that can be used in assessing environmental impact. 39 tabs., 42 figs

  18. Radiation related basic cancer research

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung Hoon; Yoo, Young Do; Hong, Seok Il [and others

    2000-04-01

    We studied the mechanism of radiation-induced apoptosis, the factors involved signaling, and the establishment of radiation-resistant cell lines in this study. During the TGF beta-stimulated epithelial mesenchymal transition(EMT), actin rearrangement occurred first and fibronectin matrix assembly followed. These two events were considered independent since cytochalasin-D did not inhibit TGF stimulated matrix assembly and fibronectin supplementation did not induce EMT. During EMT, alpha 5 beta 1 integrin and alpha v integrin have increased but MMP activation was not accompanied, which suggest that induction of extracellular matrix and activation of integrins may be main contributor for the EMT. Serum depriving induced apoptosis of HUVECs was prevented by vascular endothelial growth factor(VEGF) and PMA. The apoptosis prevention by VEGF and PMA were conformed by DNA fragmentation assay. The p53 expression level was down regulated by VEGF and PMA compared with serum deprived HUVECs. However, VEGF and PMA induces c-Myc expression level on these cells. We made the 5 radiation-resistant clones from breast, lung and cervical cancer cells. More than 70%, 100% and 50% increased resistance was detected in breast cancer cells, lung cancer cells, and cervical cells, respectively. We carried out differential display-PCR to clone the radiation-resistant genes. 9 out of 10 genes were analyzed their sequence.

  19. Radiation related basic cancer research

    International Nuclear Information System (INIS)

    Lee, Seung Hoon; Yoo, Young Do; Hong, Seok Il

    2000-04-01

    We studied the mechanism of radiation-induced apoptosis, the factors involved signaling, and the establishment of radiation-resistant cell lines in this study. During the TGF beta-stimulated epithelial mesenchymal transition(EMT), actin rearrangement occurred first and fibronectin matrix assembly followed. These two events were considered independent since cytochalasin-D did not inhibit TGF stimulated matrix assembly and fibronectin supplementation did not induce EMT. During EMT, alpha 5 beta 1 integrin and alpha v integrin have increased but MMP activation was not accompanied, which suggest that induction of extracellular matrix and activation of integrins may be main contributor for the EMT. Serum depriving induced apoptosis of HUVECs was prevented by vascular endothelial growth factor(VEGF) and PMA. The apoptosis prevention by VEGF and PMA were conformed by DNA fragmentation assay. The p53 expression level was down regulated by VEGF and PMA compared with serum deprived HUVECs. However, VEGF and PMA induces c-Myc expression level on these cells. We made the 5 radiation-resistant clones from breast, lung and cervical cancer cells. More than 70%, 100% and 50% increased resistance was detected in breast cancer cells, lung cancer cells, and cervical cells, respectively. We carried out differential display-PCR to clone the radiation-resistant genes. 9 out of 10 genes were analyzed their sequence

  20. 76 FR 59413 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-26

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee..., National Institute of Nursing Research, National Institutes of Health, 6701 Democracy Blvd., Ste. 710... Review Administrator, National Institute of Nursing Research, National Institutes of Health, 6701...

  1. Cancer systems biology: signal processing for cancer research

    Science.gov (United States)

    Yli-Harja, Olli; Ylipää, Antti; Nykter, Matti; Zhang, Wei

    2011-01-01

    In this editorial we introduce the research paradigms of signal processing in the era of systems biology. Signal processing is a field of science traditionally focused on modeling electronic and communications systems, but recently it has turned to biological applications with astounding results. The essence of signal processing is to describe the natural world by mathematical models and then, based on these models, develop efficient computational tools for solving engineering problems. Here, we underline, with examples, the endless possibilities which arise when the battle-hardened tools of engineering are applied to solve the problems that have tormented cancer researchers. Based on this approach, a new field has emerged, called cancer systems biology. Despite its short history, cancer systems biology has already produced several success stories tackling previously impracticable problems. Perhaps most importantly, it has been accepted as an integral part of the major endeavors of cancer research, such as analyzing the genomic and epigenomic data produced by The Cancer Genome Atlas (TCGA) project. Finally, we show that signal processing and cancer research, two fields that are seemingly distant from each other, have merged into a field that is indeed more than the sum of its parts. PMID:21439242

  2. Report of test and research results on atomic energy obtained in national institutes in fiscal 1985

    International Nuclear Information System (INIS)

    1986-01-01

    As for the test and research on the utilization of atomic energy in national institutes, the budget was appropriated for the first time in fiscal year 1956, and since then, the many valuable results of research have been obtained so far in the diversified fields of nuclear fusion, safety research, the irradiation of foods, medicine and others, thus the test and research accomplished the large role for promoting the utilization of atomic energy in Japan. In this report, the gists of the results of the test and research on the utilization of atomic energy carried out by national institutes in fiscal year 1985 are collected. No.1 of this report was published in 1960, and this is No.26. It is desired to increase the understanding about the recent trend and the results of the test and research on atomic energy utilization with this book. The researches on nuclear fusion, engineering safety and environmental radioactivity safety, the irradiation of foods, the countermeasures against cancer, fertilized soil, the quality improvement of brewing and farm products, the protection of farm products and the improvement of breeding, diagnosis and medical treatment, pharmaceuticals, environmental hygiene, the application to physiology and pathology, radiochemistry, radiation measurement, process analysis, nuclear reactor materials, nuclear powered ships, civil engineering, radioactivation analysis and injury prevention are reported. (Kako, I.)

  3. Prostate Cancer Stem-Like Cells | Center for Cancer Research

    Science.gov (United States)

    Prostate cancer is the third leading cause of cancer-related death among men, killing an estimated 27,000 men each year in the United States. Men with advanced prostate cancer often become resistant to conventional therapies. Many researchers speculate that the emergence of resistance is due to the presence of cancer stem cells, which are believed to be a small subpopulation of tumor cells that can self-renew and give rise to more differentiated tumor cells. It is thought that these stem cells survive initial therapies (such as chemotherapy and hormone therapy) and then generate new tumor cells that are resistant to these standard treatments. If prostate cancer stem cells could be identified and characterized, it might be possible to design treatments that prevent resistance.

  4. Automatic generation of investigator bibliographies for institutional research networking systems.

    Science.gov (United States)

    Johnson, Stephen B; Bales, Michael E; Dine, Daniel; Bakken, Suzanne; Albert, Paul J; Weng, Chunhua

    2014-10-01

    Publications are a key data source for investigator profiles and research networking systems. We developed ReCiter, an algorithm that automatically extracts bibliographies from PubMed using institutional information about the target investigators. ReCiter executes a broad query against PubMed, groups the results into clusters that appear to constitute distinct author identities and selects the cluster that best matches the target investigator. Using information about investigators from one of our institutions, we compared ReCiter results to queries based on author name and institution and to citations extracted manually from the Scopus database. Five judges created a gold standard using citations of a random sample of 200 investigators. About half of the 10,471 potential investigators had no matching citations in PubMed, and about 45% had fewer than 70 citations. Interrater agreement (Fleiss' kappa) for the gold standard was 0.81. Scopus achieved the best recall (sensitivity) of 0.81, while name-based queries had 0.78 and ReCiter had 0.69. ReCiter attained the best precision (positive predictive value) of 0.93 while Scopus had 0.85 and name-based queries had 0.31. ReCiter accesses the most current citation data, uses limited computational resources and minimizes manual entry by investigators. Generation of bibliographies using named-based queries will not yield high accuracy. Proprietary databases can perform well but requite manual effort. Automated generation with higher recall is possible but requires additional knowledge about investigators. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Manufacturing/Cell Therapy Specialist | Center for Cancer Research

    Science.gov (United States)

    Within the Leidos Biomedical Research Inc.’s Clinical Research Directorate, the Clinical Monitoring Research Program (CMRP) provides high-quality comprehensive and strategic operational support to the high-profile domestic and international clinical research initiatives of the National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Clinical Center (CC), National Institute of Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Center for Advancing Translational Sciences (NCATS), National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Mental Health (NIMH). Since its inception in 2001, CMRP’s ability to provide rapid responses, high-quality solutions, and to recruit and retain experts with a variety of backgrounds to meet the growing research portfolios of NCI, NIAID, CC, NHLBI, NIAMS, NCATS, NINDS, and NIMH has led to the considerable expansion of the program and its repertoire of support services. CMRP’s support services are strategically aligned with the program’s mission to provide comprehensive, dedicated support to assist National Institutes of Health researchers in providing the highest quality of clinical research in compliance with applicable regulations and guidelines, maintaining data integrity, and protecting human subjects. For the scientific advancement of clinical research, CMRP services include comprehensive clinical trials, regulatory, pharmacovigilance, protocol navigation and development, and programmatic and project management support for facilitating the conduct of 400+ Phase I, II, and III domestic and international trials on a yearly basis. These trials investigate the prevention, diagnosis, treatment of, and therapies for cancer, influenza, HIV, and other infectious diseases and viruses such as hepatitis C, tuberculosis, malaria, and Ebola virus; heart, lung, and blood diseases and

  6. Harnessing biodiversity: the Malagasy Institute of Applied Research (IMRA

    Directory of Open Access Journals (Sweden)

    Heys Jennifer

    2010-12-01

    Full Text Available Abstract Background Biopiracy – the use of a people’s long-established medical knowledge without acknowledgement or compensation – has been a disturbing historical reality and exacerbates the global rich-poor divide. Bioprospecting, however, describes the commercialization of indigenous medicines in a manner acceptable to the local populace. Challenges facing bioprospectors seeking to develop traditional medicines in a quality-controlled manner include a lack of skilled labor and high-tech infrastructure, adapting Northern R&D protocols to Southern settings, keeping products affordable for the local population, and managing the threat of biopiracy. The Malagasy Institute of Applied Research (IMRA has employed bioprospecting to develop new health treatments for conditions such as diabetes and burns. Because of its integration of Western science and Malagasy cultural traditions, IMRA may provide a useful example for African and other organizations interested in bioprospecting. Discussion IMRA’s approach to drug development and commercialization was adapted from the outset to Malagasy culture and Southern economic landscapes. It achieved a balance between employing Northern R&D practices and following local cultural norms through four guiding principles. First, IMRA’s researchers understood and respected local practices, and sought to use rather than resist them. Second, IMRA engaged the local community early in the drug development process, and ensured that local people had a stake in its success. Third, IMRA actively collaborated with local and international partners to increase its credibility and research capacity. Fourth, IMRA obtained foreign research funds targeting the “diseases of civilization” to cross-fund the development of drugs for conditions that affect the Malagasy population. These principles are illustrated in the development of IMRA products like Madeglucyl, a treatment for diabetes management that was developed

  7. Harnessing biodiversity: the Malagasy Institute of Applied Research (IMRA).

    Science.gov (United States)

    Puri, Manveen; Masum, Hassan; Heys, Jennifer; Singer, Peter A

    2010-12-13

    Biopiracy - the use of a people's long-established medical knowledge without acknowledgement or compensation - has been a disturbing historical reality and exacerbates the global rich-poor divide. Bioprospecting, however, describes the commercialization of indigenous medicines in a manner acceptable to the local populace. Challenges facing bioprospectors seeking to develop traditional medicines in a quality-controlled manner include a lack of skilled labor and high-tech infrastructure, adapting Northern R&D protocols to Southern settings, keeping products affordable for the local population, and managing the threat of biopiracy. The Malagasy Institute of Applied Research (IMRA) has employed bioprospecting to develop new health treatments for conditions such as diabetes and burns. Because of its integration of Western science and Malagasy cultural traditions, IMRA may provide a useful example for African and other organizations interested in bioprospecting. IMRA's approach to drug development and commercialization was adapted from the outset to Malagasy culture and Southern economic landscapes. It achieved a balance between employing Northern R&D practices and following local cultural norms through four guiding principles. First, IMRA's researchers understood and respected local practices, and sought to use rather than resist them. Second, IMRA engaged the local community early in the drug development process, and ensured that local people had a stake in its success. Third, IMRA actively collaborated with local and international partners to increase its credibility and research capacity. Fourth, IMRA obtained foreign research funds targeting the "diseases of civilization" to cross-fund the development of drugs for conditions that affect the Malagasy population. These principles are illustrated in the development of IMRA products like Madeglucyl, a treatment for diabetes management that was developed from a traditional remedy. By combining local and international

  8. Environmental Survey preliminary report, Solar Energy Research Institute, Golden, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    1988-10-01

    This report presents the preliminary findings of the first phase of the Environmental Survey of the US Department of Energy's (DOE) Solar Energy Research Institute (SERI), conducted December 14 through 18, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. The team includes outside experts supplied by private contractors. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with SERI. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. The on-site phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at SERI, and interviews with site personnel. 33 refs., 22 figs., 21 tabs.

  9. Psychiatric genetic research at the National Institute of Mental Health

    Energy Technology Data Exchange (ETDEWEB)

    Berg, K.; Mullican, C.; Maestri, N. [NIMH/NIH, Rockville, MD (United States)] [and others

    1994-12-15

    For some time it has been known through the results of family, twin, and adoption studies that hereditary appears to play a significant casual role in many mental disorders, including schizophrenia, bipolar disorder, and other mood disorders, Alzheimer`s Disease, panic disorder, obsessive compulsive disorder, autism, dyslexia, and Tourette`s syndrome. The precise patterns of inheritance of these complex disorders have not been determined, nor have the relevant genes been localized or cloned. Because the genetics are complex and because there is also clearly an environmental contribution to behavior, we expect the analysis of the genetics of mental illness to be arduous and not quickly resolved. There are several compelling reasons to continue to focus our attention on uncovering the genetic factors for severe mental illness. Prominent among these are the implications for better treatment of mental disorders. The National Institute of Mental Health supports a wide range of studies on psychiatric genetic research. 16 refs.

  10. Maximizing Institutional Research Impact through Building Relationships and Collaborating within the Institution

    Science.gov (United States)

    Kirby, Yvonne Kochera; Floyd, Nancy D.

    2015-01-01

    Building and maintaining relationships within the institution with shared goals for preserving compliance and presenting an accurate portrait of the institution is critical for effective external reporting. It can also provide immeasurable internal benefit to information stakeholders.

  11. High hospital research participation and improved colorectal cancer survival outcomes: a population-based study

    OpenAIRE

    Downing, A.; Morris, E. J.; Corrigan, N.; Sebag-Montefiore, D.; Finan, P. J.; Thomas, J. D.; Chapman, M.; Hamilton, R.; Campbell, H.; Cameron, D.; Kaplan, R.; Parmar, M.; Stephens, R.; Seymour, M.; Gregory, W.

    2017-01-01

    Objective: In 2001, the National Institute for Health Research (NIHR) Cancer Research Network (NCRN) was established, leading to a rapid increase in clinical research activity across the English NHS. Using colorectal cancer (CRC) as an example, we test the hypothesis that high, sustained hospital-level participation in interventional clinical trials improves outcomes for all CRC patients managed in those research-intensive hospitals. Design: Data for patients diagnosed with CRC in England in ...

  12. TCGA researchers identify 4 subtypes of stomach cancer

    Science.gov (United States)

    Stomach cancers fall into four distinct molecular subtypes, researchers with The Cancer Genome Atlas (TCGA) Network have found. Scientists report that this discovery could change how researchers think about developing treatments for stomach cancer, also c

  13. Oceanographic Research of Marine Hydrophysical Institute in the Southern Ocean

    Directory of Open Access Journals (Sweden)

    Yu.V. Artamonov

    2016-12-01

    Full Text Available Basic stages of the oceanographic research carried out by Marine Hydrophysical Institute in the Southern ocean are considered. Each stage of the studies is illustrated by the schemes of expeditionary work; the most important results are presented. The oceanographic studies of Marine Hydrophysical Institute in the Southern ocean are shown to be developed in two basic directions: marine expeditionary research and analysis of the archival hydrometeorological data. Based on the results of expeditionary studies, the mechanisms of formation and variability of the water structure and circulation in the Antarctic coastal regions are described. Anomalies of hydrometeorological fields occurring along the route to Antarctica are assessed due to the measurements from the passing vessels. The archival hydrological and satellite data constitute a foundation for revealing the features of seasonal and interannual variability of the ocean surface temperature, fronts and sea ice in Antarctica. The effect of El Niño events on the interannual variation of the characteristics of Scotia Sea Front is revealed. It is shown that the formation of warm water positive anomaly areas in the tropical Pacific is caused by El Niño events. It’s accompanied by an appreciable displacement of the front to the south, by the weakening of its intensity and the decrease of temperature on the front axes. It is shown that maximum seasonal variation of the ice concentration is observed in the Weddell and Lazarev Seas. The ice in the Weddell, Amundsen and Bellingshausen Sea are shown to be exposed to the highest interannual variability.

  14. Report of test and research results on atomic energy obtained in national institutes in fiscal 1984

    International Nuclear Information System (INIS)

    1985-01-01

    The test and research regarding the utilization of atomic energy carried out in national institutions have produced many valuable results in diverse fields so far, such as nuclear fusion, safety research, food irradiation and medicine, since the budget had been appropriated for the first time in 1956. It has accomplished large role in the promotion of atomic energy utilization in Japan. This report is Volume 25, in which the results of the test and research on atomic energy utilization carried out by national institutions in fiscal year 1984 are summarized. It is hoped that the understanding about the recent trend and the results of the test and research on atomic energy utilization is further promoted by this report. The contents of this report are nuclear fusion; the research on engineering safety and environmental radioactivity safety; food irradiation; the countermeasures against cancer; fertilized soil, the improvement of quality, the protection of plants and the improvement of breeding in agriculture and fishery fields; diagnosis and medical treatment, pharmaceuticals, environmental hygiene and the application to physiology and pathology in medical field; radiation chemistry and radiation measurement in mining and industry fields; nuclear reactor materials and nuclear-powered ships; civil engineering; radioactivation analysis; and the research on the prevention of injuries. (Kako, I.)

  15. Antiproton radiation found effective in cancer research

    CERN Multimedia

    2003-01-01

    "An international collaboration of scientists has completed the first ever antiproton beam experiments designed to reveal the biological effectiveness of antiproton radiation in terminating cells used for cancer research...PBar Labs assembled the collaboration at CERN (European Organization for Nuclear Research in Geneva) to perform the measurements" (1 page).

  16. The state of research funding from the National Institutes of Health for criminal justice health research.

    Science.gov (United States)

    Ahalt, Cyrus; Bolano, Marielle; Wang, Emily A; Williams, Brie

    2015-03-03

    Over 20 million Americans are currently or have been incarcerated. Most are from medically underserved populations; 1 in 3 African American men and 1 in 6 Latino men born in 2001 are projected to go to prison during their lifetime. The amount of funding from the National Institutes of Health (NIH) to understand and improve the health of persons involved with the criminal justice system is unknown. To describe NIH funding for research on the health and health care needs of criminal justice-involved persons. Review of NIH grants (2008-2012) in the RePORT (Research Portfolio Online Reporting Tools) database. U.S. criminal justice system. Criminal justice-involved persons participating in NIH-funded clinical research. NIH research and training grants awarded, by number, type, research area, institute or center, and dollar amount. Of more than 250 000 NIH-funded grants, 180 (<0.1%) focused on criminal justice health research. The 3 most common foci were substance use or HIV (64%), mental health (11%), and juvenile health (8%). The National Institute on Drug Abuse and the National Institute of Mental Health funded 78% of all grants. In 2012, the NIH invested $40.9 million in criminal justice health research, or 1.5% of the $2.7 billion health disparities budget for that year. NIH-supported research that did not explicitly include current or former prisoners but may have relevance to criminal justice health was not included. Federal funding for research focused on understanding and improving the health of criminal justice-involved persons is small, even compared with the NIH's overall investment in health disparities research. The NIH is well-positioned to transform the care of current and former prisoners by investing in this critical yet overlooked research area.

  17. An internal health systems research portfolio assessment of a low-income country research institution

    Directory of Open Access Journals (Sweden)

    Gazi Rukshana

    2010-04-01

    Full Text Available Abstract Background In order to determine the type and amount of health systems research being conducted within ICDDR,B (also known as the Centre, a leading research institution in Bangladesh, an internal review of all on-going research protocols was conducted in September 2007. Methods A review of all ongoing research protocols within the Centre was conducted. The names of the investigators and the institutional divisions of the protocols were removed in order to decrease the amount of reviewer bias. The building blocks of the World Health Organization's "Framework for Action" on health systems was used to categorize the protocols considered to be health systems research projects. Several additional items were collected, e.g. the highest level of education completed by the Principal Investigator. A total dollar value was placed on the health systems research portfolio of the institution based on the budgets of the selected protocols. Results As of September 2007 16 out of 118 (13.5% reviewed protocols were considered to be health systems research projects. Results of the six building blocks of the health system categorization demonstrated that a majority of these protocols involved elements of health services delivery. There was very little engagement in more downstream systems and policy research that involved leadership and governance of the health system. Eleven of the HSR studies were local in scope, while there was only one study that has a multinational focus. The Centre's total dollar value for the health systems research project portfolio added up to US$ 3,723,331. Conclusions This internal review can serve as a snap shot of on-going activities, and as a baseline for future assessments against which to monitor progress in the area of health systems research. Further, it can serve as a model for other institutions striving to assess and develop health systems research programmes and capacity.

  18. Variation in Definitive Therapy for Localized Non-Small Cell Lung Cancer Among National Comprehensive Cancer Network Institutions

    Energy Technology Data Exchange (ETDEWEB)

    Valle, Luca F. [Geisel School of Medicine at Dartmouth College, Dartmouth College, Hanover, New Hampshire (United States); Jagsi, Reshma [Department of Radiation Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan (United States); Bobiak, Sarah N.; Zornosa, Carrie [National Comprehensive Cancer Network, Fort Washington, Pennsylvania (United States); D' Amico, Thomas A. [Department of Surgery, Division of Thoracic Surgery, Duke Cancer Institute, Durham, North Carolina (United States); Pisters, Katherine M. [Department of Thoracic/Head and Neck Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Dexter, Elisabeth U. [Department of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, New York (United States); Niland, Joyce C. [Department of Information Sciences, City of Hope Comprehensive Cancer Center, Duarte, California (United States); Hayman, James A. [Department of Radiation Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan (United States); Kapadia, Nirav S., E-mail: Nirav.S.Kapadia@hitchcock.org [Department of Radiation Oncology, Dartmouth-Hitchcock Norris Cotton Cancer Center, Lebanon, New Hampshire (United States); Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire (United States)

    2016-02-01

    Purpose: This study determined practice patterns in the staging and treatment of patients with stage I non-small cell lung cancer (NSCLC) among National Comprehensive Cancer Network (NCCN) member institutions. Secondary aims were to determine trends in the use of definitive therapy, predictors of treatment type, and acute adverse events associated with primary modalities of treatment. Methods and Materials: Data from the National Comprehensive Cancer Network Oncology Outcomes Database from 2007 to 2011 for US patients with stage I NSCLC were used. Main outcome measures included patterns of care, predictors of treatment, acute morbidity, and acute mortality. Results: Seventy-nine percent of patients received surgery, 16% received definitive radiation therapy (RT), and 3% were not treated. Seventy-four percent of the RT patients received stereotactic body RT (SBRT), and the remainder received nonstereotactic RT (NSRT). Among participating NCCN member institutions, the number of surgeries-to-RT course ratios varied between 1.6 and 34.7 (P<.01), and the SBRT-to-NSRT ratio varied between 0 and 13 (P=.01). Significant variations were also observed in staging practices, with brain imaging 0.33 (0.25-0.43) times as likely and mediastinoscopy 31.26 (21.84-44.76) times more likely for surgical patients than for RT patients. Toxicity rates for surgical and for SBRT patients were similar, although the rates were double for NSRT patients. Conclusions: The variations in treatment observed among NCCN institutions reflects the lack of level I evidence directing the use of surgery or SBRT for stage I NSCLC. In this setting, research of patient and physician preferences may help to guide future decision making.

  19. Neuroendocrine Carcinoma: Immunohistochemistry Department Of Cancer Institute 1996 - 2000

    Directory of Open Access Journals (Sweden)

    Yazdani F

    2003-07-01

    Full Text Available Dispersed neuroendocrine system (D.N.S consists of a wide variety of cells that are present in the central and peripheral nervous system and in many classic endocrine organs and different tissues such as respiratory and gastrointestinal tracts, skin, prostate, breast and also their neoplasm show neuroendocrine differentiation by electron microscopy, immunohistochemistry or biochemical techniques:"nMaterials and Methods: The present study has been carried out by case-series method in order to evaluating the characteristics of all types of neuroendocrine carcinoma: different anatomical locations during 5 years period in immunohistochemistry department of cancer institute."nResults: The diagnosis of 109 cases of neuroendocrine carcinoma consisting of neuroendocrine carcinoma, small cell carcinoma, medullary carcinoma of thyroid, carcinoid tumor and merkel cell carcinoma are confirmed that among them the most common diagnosis was related to neuroendocrine carcinoma (50.5 percent. The most prevalent age group was 40-49 years and male to female distribution were 56 percent and 44 percent respectively. Anatomical distribution of tumor show that about 30 percent of cases were metastatic carcinoma, 30 percent in thyroid, respiratory tract and head and neck region and remainder in a variety of tissues. In over 50 percent of cases one of endocrinoid patterns as trabecular, organoid or mixed of them were seen."nConclusion: Immunohistochemically N.S.E (Neuron Specific Enolase show high sensitivity with 96 percent positive reaction and more specific endocrine markers as chromogranin A in 80 percent and synaptophysin only in 24 percent because of lesser application of the latter. Also epithelial markers such as cytokeratin and E.M.A."n(Epithelial Membrane Antigen were positive in 69 percent and 74 percent respectively. Mean survival rate of all neuroendocrine carcinoma reached to 4.8 years with lowest survival of 4.3 years among small cell carcinoma and

  20. Research on Immunotherapy: Using the Immune System to Treat Cancer

    Science.gov (United States)

    ... Home Research Key Initiatives Immunotherapy NCI’s Role in Immunotherapy Research An oral squamous cancer cell (white) being ... immunotherapy to more patients with cancer. NCI-Supported Immunotherapy Research Immunotherapy research funded by or conducted at ...

  1. Prevalence and Predictors of Neoadjuvant Therapy for Stage IIIA Non-Small Cell Lung Cancer in the National Cancer Database: Importance of Socioeconomic Status and Treating Institution

    International Nuclear Information System (INIS)

    Sher, David J.; Liptay, Michael J.; Fidler, Mary Jo

    2014-01-01

    Purpose: The optimal locoregional therapy for stage IIIA non-small cell lung cancer (NSCLC) is controversial, with definitive chemoradiation therapy (CRT) and neoadjuvant therapy followed by surgery (NT-S) serving as competing strategies. In this study, we used the National Cancer Database to determine the prevalence and predictors of NT in a large, modern cohort of patients. Methods and Materials: Patients with stage IIIA NSCLC treated with CRT or NT-S between 2003 and 2010 at programs accredited by the Commission on Cancer were included. Predictors were categorized as clinical, time/geographic, socioeconomic, and institutional. In accord with the National Cancer Database, institutions were classified as academic/research program and as comprehensive and noncomprehensive community cancer centers. Logistic regression and random effects multilevel logistic regression were performed for univariable and multivariable analyses, respectively. Results: The cohort consisted of 18,581 patients, 3,087 (16.6%) of whom underwent NT-S (10.6% induction CRT, 6% induction chemotherapy). The prevalence of NT-S was constant over time, but there were significant relative 31% and 30% decreases in pneumonectomy and right-sided pneumonectomy, respectively, over time (P trend <.02). In addition to younger age, lower T stage, and favorable comorbidity score, indicators of higher socioeconomic status were strong independent predictors of NT-S, including white race, higher income, and private/managed insurance. The type of institution (academic/research program vs comprehensive or noncomprehensive community cancer centers, odds ratio 1.54 and 2.08, respectively) strongly predicted NT-S, but treatment volume did not. Conclusions: Neoadjuvant therapy followed by surgery was an uncommon treatment approach in Commission on Cancer programs, and the prevalence of postinduction pneumonectomy decreased over time. Higher socioeconomic status and treatment at academic institutions were significant

  2. 78 FR 7794 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-04

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee..., Office of Review, National Institute of Nursing Research, National Institutes of Health, 6701 Democracy...: National Institute of Nursing Research Special Emphasis Panel, Fellowship & Mentored Research Scientist...

  3. Prostate Cancer Research Training Program

    Science.gov (United States)

    2012-05-01

    brief description of research in the la boratories of each University of Iowa mentor. At this point in time the program is 8 weeks long...www.uihealthcare.com/depts/med/urology/urolo gymds/luo.html A major research project in our la boratory is to develop a novel therapeutic...wright.shtml?menu =1&tab=facultyTab The Wright Labo ratory is focuse d on defining the composition, activity, and overall cellul ar function of

  4. Locally advance breast cancer survival after radiotherapy following mastectomy at the National Cancer Institute of Colombia

    International Nuclear Information System (INIS)

    Ospino, Rosalba; Cendales, Ricardo; Cifuentes, Javier; Sanchez, Zayda; Galvis, Juan; Bobadilla, Ivan

    2010-01-01

    Objective: To evaluate survival after treatment with mastectomy and teletherapy for locally advance breast cancer at the National Cancer Institute of Colombia. Methods: A case serie analysis was conducted. Frequencies and measures of central tendency were applied. Locoregional relapse free survival, disease free survival and overall survival were determined with Kaplan-Meyer and Cox regression analyses. Results: 174 patiens were included. Most of the patients corresponded to ductal tumors with positive axillary nodes and hormone receptors. The treatment was neoadjuvant chemotherapy, mastectomy, axillary nodes resection, radiotherapy, and adjuvant hormone therapy. The 5-years locoregional relapse free survival was 88.8%, disease free survival was 63.3%, and overall survival 84.4%. Conclusions: The results are similar to previous reports. Breast reconstruction was associated with a greater chance of locoregional relapse. The node rate is a relevant predictor for overall survival, disease free survival, and locoregional relapse free survival, and tumor grade for the former two.

  5. Locally advance breast cancer survival after radiotherapy following mastectomy at the National Cancer Institute of Colombia

    International Nuclear Information System (INIS)

    Ospino, Rosalba; Cendales, Ricardo; Cifuentes, Javier; Sanchez, Zayda; Galvis, Juan; Bobadilla, Ivan

    2009-01-01

    Objective: To evaluate survival after treatment with mastectomy and teletherapy for locally advance breast cancer at the National Cancer Institute of Colombia. Methods: A case serie analysis was conducted. Frequencies and measures of central tendency were applied. Locoregional relapse free survival, disease free survival and overall survival were determined with Kaplan-Meyer and Cox regression analyses. Results: 174 patients were included. Most of the patients corresponded to ductal tumors with positive axillary nodes and hormone receptors. The treatment was neoadjuvant chemotherapy, mastectomy, axillary nodes resection, radiotherapy, and adjuvant hormone therapy. The 5-years locoregional relapse free survival was 88.8%, disease free survival was 63.3%, and overall survival 84.4%. Conclusions: The results are similar to previous reports. Breast reconstruction was associated with a greater chance of locoregional relapse. The node rate is a relevant predictor for overall survival, disease free survival, and locoregional relapse free survival, and tumor grade for the former two.

  6. Rethinking cancer: current challenges and opportunities in cancer research

    Science.gov (United States)

    Cagan, Ross; Meyer, Pablo

    2017-01-01

    ABSTRACT Cancer therapeutics currently have the lowest clinical trial success rate of all major diseases. Partly as a result of the paucity of successful anti-cancer drugs, cancer will soon be the leading cause of mortality in developed countries. As a disease embedded in the fundamentals of our biology, cancer presents difficult challenges that would benefit from uniting experts from a broad cross-section of related and unrelated fields. Combining extant approaches with novel ones could help in tackling this challenging health problem, enabling the development of therapeutics to stop disease progression and prolong patient lives. This goal provided the inspiration for a recent workshop titled ‘Rethinking Cancer’, which brought together a group of cancer scientists who work in the academic and pharmaceutical sectors of Europe, America and Asia. In this Editorial, we discuss the main themes emerging from the workshop, with the aim of providing a snapshot of key challenges faced by the cancer research community today. We also outline potential strategies for addressing some of these challenges, from understanding the basic evolution of cancer and improving its early detection to streamlining the thorny process of moving promising drug targets into clinical trials. PMID:28381596

  7. 77 FR 35991 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-06-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane, Suite 4075, Bethesda.... 93.172, Human Genome Research, National Institutes of Health, HHS) Dated: June 8, 2012. Jennifer S...

  8. 75 FR 8977 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-02-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome..., National Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane, Suite 4076, MSC..., Human Genome Research, National Institutes of Health, HHS) Dated: February 18, 2010. Jennifer Spaeth...

  9. 75 FR 53703 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-09-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome..., Scientific Review Branch, National Human Genome Research Institute, National Institutes of Health, 5635.... (Catalogue of Federal Domestic Assistance Program Nos. 93.172, Human Genome Research, National Institutes of...

  10. 77 FR 74676 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-12-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane, Suite 4075, Bethesda.... 93.172, Human Genome Research, National Institutes of Health, HHS) Dated: December 11, 2012. David...

  11. 75 FR 67380 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-11-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Review Branch, National Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane.... (Catalogue of Federal Domestic Assistance Program Nos. 93.172, Human Genome Research, National Institutes of...

  12. 77 FR 8268 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... applications. Place: National Human Genome Research Institute, 5635 Fisher's Lane, Room 4076, Rockville, MD..., CIDR, National Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane, Suite...

  13. 78 FR 21382 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2013-04-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... applications. Place: National Human Genome Research Institute, Suite 4076, 5635 Fisher's Lane, Bethesda, MD..., National Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane, Suite 4075...

  14. 76 FR 10909 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-02-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome..., National Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane, Suite 4076, MSC..., Human Genome Research, National Institutes of Health, HHS). Dated: February 18, 2011. Jennifer S. Spaeth...

  15. Impact of the Cancer Prevention and Control Research Network

    Science.gov (United States)

    Ribisl, Kurt M.; Fernandez, Maria E.; Friedman, Daniela B.; Hannon, Peggy; Leeman, Jennifer; Moore, Alexis; Olson, Lindsay; Ory, Marcia; Risendal, Betsy; Sheble, Laura; Taylor, Vicky; Williams, Rebecca; Weiner, Bryan J.

    2018-01-01

    The Cancer Prevention and Control Research Network (CPCRN) is a thematic network dedicated to accelerating the adoption of evidence-based cancer prevention and control practices in communities by advancing dissemination and implementation science. Funded by the Centers for Disease Control and Prevention and National Cancer Institute, CPCRN has operated at two levels: Each participating Network Center conducts research projects with primarily local partners as well as multicenter collaborative research projects with state and national partners. Through multicenter collaboration, thematic networks leverage the expertise, resources, and partnerships of participating centers to conduct research projects collectively that might not be feasible individually. Although multicenter collaboration often is advocated, it is challenging to promote and assess. Using bibliometric network analysis and other graphical methods, this paper describes CPCRN’s multicenter publication progression from 2004 to 2014. Searching PubMed, Scopus, and Web of Science in 2014 identified 249 peer-reviewed CPCRN publications involving two or more centers out of 6,534 total. The research and public health impact of these multicenter collaborative projects initiated by CPCRN during that 10-year period were then examined. CPCRN established numerous workgroups around topics such as: 2-1-1, training and technical assistance, colorectal cancer control, federally qualified health centers, cancer survivorship, and human papillomavirus. The paper discusses the challenges that arise in promoting multicenter collaboration and the strategies that CPCRN uses to address those challenges. The lessons learned should broadly interest those seeking to promote multisite collaboration to address public health problems, such as cancer prevention and control. PMID:28215371

  16. New Funding Opportunity: Tissue Purchase Order Acquisitions | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The National Cancer Institute (NCI) is expanding its basic and translational research programs that rely heavily on sufficient availability of high quality, well annotated biospecimens suitable for use in genomic and proteomic studies.  The NCI’s overarching goal with such programs is to improve the ability to diagnose, treat, and prevent cancer.

  17. New Funding Opportunity: Biospecimen Core Resource | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The purpose of this notice is to notify the community that the National Cancer Institute's (NCI’s) Office of Cancer Clinical Proteomics Research (OCCPR) is seeking sources to establish a Biospecimen Core Resource (BCR), capable of receiving, qualifying, processing, and distributing annotated biospecimens.

  18. Institutional Memory Preservation at NASA Glenn Research Center

    Science.gov (United States)

    Coffey, J.; Moreman, Douglas; Dyer, J.; Hemminger, J. A.

    1999-01-01

    In this era of downsizing and deficit reduction, the preservation of institutional memory is a widespread concern for U.S. companies and governmental agencies. The National Aeronautical and Space Administration faces the pending retirement of many of the agency's long-term, senior engineers. NASA has a marvelous long-term history of success, but the agency faces a recurring problem caused by the loss of these engineers' unique knowledge and perspectives on NASA's role in aeronautics and space exploration. The current work describes a knowledge elicitation effort aimed at demonstrating the feasibility of preserving the more personal, heuristic knowledge accumulated over the years by NASA engineers, as contrasted with the "textbook" knowledge of launch vehicles. Work on this project was performed at NASA Glenn Research Center and elsewhere, and focused on launch vehicle systems integration. The initial effort was directed toward an historic view of the Centaur upper stage which is powered by two RL-10 engines. Various experts were consulted, employing a variety of knowledge elicitation techniques, regarding the Centaur and RL-10. Their knowledge is represented in searchable Web-based multimedia presentations. This paper discusses the various approaches to knowledge elicitation and knowledge representation employed, and assesses successes and challenges in trying to perform large-scale knowledge preservation of institutional memory. It is anticipated that strategies for knowledge elicitation and representation that have been developed in this grant will be utilized to elicit knowledge in a variety of domains including the complex heuristics that underly use of simulation software packages such as that being explored in the Expert System Architecture for Rocket Engine Numerical Simulators.

  19. Automation of Technology for Cancer Research.

    Science.gov (United States)

    van der Ent, Wietske; Veneman, Wouter J; Groenewoud, Arwin; Chen, Lanpeng; Tulotta, Claudia; Hogendoorn, Pancras C W; Spaink, Herman P; Snaar-Jagalska, B Ewa

    2016-01-01

    Zebrafish embryos can be obtained for research purposes in large numbers at low cost and embryos develop externally in limited space, making them highly suitable for high-throughput cancer studies and drug screens. Non-invasive live imaging of various processes within the larvae is possible due to their transparency during development, and a multitude of available fluorescent transgenic reporter lines.To perform high-throughput studies, handling large amounts of embryos and larvae is required. With such high number of individuals, even minute tasks may become time-consuming and arduous. In this chapter, an overview is given of the developments in the automation of various steps of large scale zebrafish cancer research for discovering important cancer pathways and drugs for the treatment of human disease. The focus lies on various tools developed for cancer cell implantation, embryo handling and sorting, microfluidic systems for imaging and drug treatment, and image acquisition and analysis. Examples will be given of employment of these technologies within the fields of toxicology research and cancer research.

  20. Summer Prostate Cancer Research Training Program

    Science.gov (United States)

    2017-09-01

    the research program by each mentor will certainly produce important research findings, aided in part by the summer research of the ...adenovirus vaccine in men with prostate cancer. Important in these trials is the safety of the vaccine and its ability to induce anti-tumor immunity... Living in Iowa City for the Summer Housing and Meals - All students will be housed in the Mayflower Residence Hall on the Campus of the University

  1. Senior Laboratory Animal Technician | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused on the design, generation, characterization and application of genetically engineered and biological animal models of human disease, which are aimed at the development of targeted diagnostics and therapies. LASP contributes to advancing human health, developing new treatments, and improving existing treatments for cancer and other diseases while ensuring safe and humane treatment of animals. KEY ROLES/RESPONSIBILITIES The Senior Laboratory Animal Technician will be responsible for: Daily tasks associated with the care, breeding and treatment of research animals for experimental purposes Management of rodent breeding colonies consisting of multiple, genetically complex strains and associated record keeping and database management Colony management procedures including: tail clipping, animal identification, weaning Data entry consistent with complex colony management Collection of routine diagnostic samples Coordinating shipment of live animals and specimens Performing rodent experimental procedures including basic necropsy and blood collection Observation and recording of physical signs of animal health Knowledge of safe working practices using chemical carcinogen and biological hazards Work schedule may include weekend and holiday hours This position is in support of the Center for Cancer Research (CCR).

  2. Engaging Undergraduates in a Unique Neuroscience Research Opportunity: A Collaborative Research Experience Between a Primarily Undergraduate Institution (PUI) and a Major Research Institution.

    Science.gov (United States)

    Kreitzer, Matthew A; Malchow, Robert P

    2013-01-01

    This report describes a unique undergraduate research and teaching collaboration between investigators at two institutions, one a relatively small, primarily undergraduate institution and the other a large, urban research-intensive university. The program incorporates three major facets. First, undergraduates participate in a weekly collaborative lab meeting involving instructors from both institutions and held via remote video. Student-led discussions and presentations dominate these meetings, and the unique format promotes novel interactions between students and instructors. Second, students carry out investigative studies centered on understanding the role extracellular pH dynamics play in regulating neuronal processing. Students carry out studies on isolated neurons and glia throughout the fall and spring semesters, and primarily use a noninvasive electrophysiological technique, termed self-referencing, for extracellular pH measurements. The technique is relatively simple and readily learned and employed by undergraduates, while still being powerful enough to provide novel and meaningful research results. The research component is expanded for several students each summer who are selected to participate in summer research with both PIs and graduate students at the major research institution. Finally results gathered during the year and over the summer are disseminated at institutional symposia, undergraduate neuroscience symposia, national society meetings, and in submitted journal manuscripts. Preliminary observations and findings over three years support the aim of this research experience; to create a productive environment that facilitates deep-level understanding of neurophysiological concepts at the undergraduate level and promotes intellectual development while cultivating an excitement for scientific inquiry in the present and future.

  3. Engaging Undergraduates in a Unique Neuroscience Research Opportunity: A Collaborative Research Experience Between a Primarily Undergraduate Institution (PUI) and a Major Research Institution

    Science.gov (United States)

    Kreitzer, Matthew A.; Malchow, Robert P.

    2013-01-01

    This report describes a unique undergraduate research and teaching collaboration between investigators at two institutions, one a relatively small, primarily undergraduate institution and the other a large, urban research-intensive university. The program incorporates three major facets. First, undergraduates participate in a weekly collaborative lab meeting involving instructors from both institutions and held via remote video. Student-led discussions and presentations dominate these meetings, and the unique format promotes novel interactions between students and instructors. Second, students carry out investigative studies centered on understanding the role extracellular pH dynamics play in regulating neuronal processing. Students carry out studies on isolated neurons and glia throughout the fall and spring semesters, and primarily use a noninvasive electrophysiological technique, termed self-referencing, for extracellular pH measurements. The technique is relatively simple and readily learned and employed by undergraduates, while still being powerful enough to provide novel and meaningful research results. The research component is expanded for several students each summer who are selected to participate in summer research with both PIs and graduate students at the major research institution. Finally results gathered during the year and over the summer are disseminated at institutional symposia, undergraduate neuroscience symposia, national society meetings, and in submitted journal manuscripts. Preliminary observations and findings over three years support the aim of this research experience; to create a productive environment that facilitates deep-level understanding of neurophysiological concepts at the undergraduate level and promotes intellectual development while cultivating an excitement for scientific inquiry in the present and future. PMID:24319396

  4. About the Breast and Gynecologic Cancer Research Group | Division of Cancer Prevention

    Science.gov (United States)

    The Breast and Gynecologic Cancer Research Group conducts and fosters the development of research on the prevention and early detection of breast cancer, cervix and human papillomavirus (HPV)-related cancers, endometrial cancers, ovarian cancers, and precursor conditions related to these cancers. |

  5. Assessing the scientific research productivity of Puerto Rican cancer researchers: bibliometric analysis from the Science Citation Index.

    Science.gov (United States)

    Calo, William A; Suárez-Balseiro, Carlos; Suárez, Erick; Soto-Salgado, Marievelisse; Santiago-Rodríguez, Eduardo J; Ortiz, Ana P

    2010-09-01

    The analysis of cancer scientific production in Puerto Rico is largely unexplored. The objective of this study was to characterize trends in cancer-related research publications by authors affiliated to Puerto Rican institutions in recent decades. Manuscripts were retrieved from the Science Citation Index (SCI) database from 1982 to 2009. Search criterions were that the author's affiliation field contained some institution located in Puerto Rico and that the manuscripts were related to cancer research (according to keywords from the National Cancer Institute' cancer definition). Indexes measured in our analysis included number and type of manuscript, scientific collaboration, author's affiliation, and journal visibility. All the analyses were conducted using ProCite for bibliographic information management and STATA and SEER Joinpoint for the statistical inquiry. From 1982-2009, cancer-related papers authored by scientists located in Puerto Rico came to 451. Over the last three decades the scientific production underwent significant growth (APC = 6.4%, p scientific production in Puerto Rico underwent constant growth during the last three decades. A complete understanding of citing, publishing, and collaboration patterns in Puerto Rico is critical to researchers, policy makers, and health-care professionals in order to make informed decisions about cancer research priorities.

  6. Institutional Barriers to Research on Sensitive Topics: Case of Sex Communication Research Among University Students

    Directory of Open Access Journals (Sweden)

    Carey M. Noland

    2012-11-01

    Full Text Available When conducting research on sensitive topics, it is challenging to use new methods of data collection given the apprehensions of Institutional Review Boards (IRBs. This is especially worrying because sensitive topics of research often require novel approaches. In this article a brief personal history of navigating the IRB process for conducting sex communication research is presented, along with data from a survey that tested the assumptions long held by many IRBs. Results support some of the assumptions IRBs hold about sex communication research, but do not support some other assumptions.

  7. Bringing institutions into performance persistence research: Exploring the impact of product, financial, and labor market institutions

    OpenAIRE

    Aya S Chacar; William Newburry; Balagopal Vissa

    2010-01-01

    This study challenges the implicit assumption of homogeneity in national institutional environments made in past studies of firm performance persistence. We propose that home-country institutions matter. We focus on the impact of formal institutions in the product, financial, and labor markets, arguing that they affect the size of pools of exchange partners and the types of exchanges allowed and condoned. Ultimately, these restrictions affect competitive intensity among firms, and firm perfor...

  8. Pioneer Valley Life Sciences Institute Translational Biomedical Research

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, Sallie; Shao, Rong; Schwartz, Lawrence; Jerry, D Joseph

    2012-09-20

    1. Analysis of angiogenic factors in breast cancer angiogenesis. Determine whether Acheron and YKL-40 were elevated in subsets of primary breast cancers and if they participated directly in determining the behavior of tumors. 2. Use of polymers for chemotherapeutic delivery to breast cancer tumors. The experiments were designed to define the utility of biocompatible polymers for addressing certain limitations and establish a flexible platform for delivery of diverse compound.

  9. Key Features of Research Portal for Stimulating Research in Institutions of Higher Technical Education

    Science.gov (United States)

    Agarwal, Parul Dharmani; Kiran, Ravi; Verma, Anil Kumar

    2012-01-01

    Problem Statement: The current higher learning institutions in developed countries have adapted to their changing role in a knowledge-based society It is time for developing countries like India to focus on Knowledge Management thus, the current study presents research undertaken in understanding the implication of Knowledge Management in the…

  10. 78 FR 9707 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... clearly unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research... Officer, Scientific Review Branch, National Human Genome Research Institute, 5635 Fishers Lane, Suite 4076...

  11. 77 FR 20646 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-04-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... clearly unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research.... Agenda: To review and evaluate grant applications. Place: National Human Genome Research Institute, 5635...

  12. 77 FR 58402 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-20

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... clearly unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research...: To review and evaluate grant applications. Place: National Human Genome Research Institute, 5635...

  13. 77 FR 59933 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-10-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... clearly unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research....D., Scientific Review Officer, Scientific Review Branch, National Human Genome Research Institute...

  14. 75 FR 10488 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-03-08

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... clearly unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research...- 4280, [email protected] . Name of Committee: National Human Genome Research Institute Special...

  15. Prostate Cancer Research Trial Helps John Spencer Treat His Cancer | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Prostate Cancer Prostate Cancer Research Trial Helps John Spencer Treat His Cancer ... because of timely detection and treatment of his prostate cancer. He participated in an NIH-sponsored clinical trial. ...

  16. Conducting Molecular Epidemiological Research in the Age of HIPAA: A Multi-Institutional Case-Control Study of Breast Cancer in African-American and European-American Women

    Directory of Open Access Journals (Sweden)

    Christine B. Ambrosone

    2009-01-01

    Full Text Available Breast cancer in African-American (AA women occurs at an earlier age than in European-American (EA women and is more likely to have aggressive features associated with poorer prognosis, such as high-grade and negative estrogen receptor (ER status. The mechanisms underlying these differences are unknown. To address this, we conducted a case-control study to evaluate risk factors for high-grade ER- disease in both AA and EA women. With the onset of the Health Insurance Portability and Accountability Act of 1996, creative measures were needed to adapt case ascertainment and contact procedures to this new environment of patient privacy. In this paper, we report on our approach to establishing a multicenter study of breast cancer in New York and New Jersey, provide preliminary distributions of demographic and pathologic characteristics among case and control participants by race, and contrast participation rates by approaches to case ascertainment, with discussion of strengths and weaknesses.

  17. A research on the enhancement of research management efficiency for the division of research, Korea cancer center hospital

    International Nuclear Information System (INIS)

    Lee, S. W.; Ma, K. H.; Kim, J. R.; Lee, D. C.; Lee, J. H.

    1999-06-01

    The research activities of Korea Cancer Center Hospital have increased for the past a few years just in proportion to the increase of research budget, but the assisting manpower of the office of research management has never been increased and the indications are that the internal and external circumstances will not allow the recruitment for a fairly long time. It has, therefore, become inevitable to enhance the work efficiency of the office by analyzing the administrative research assistance system, finding out problems and inefficiency factors, and suggesting possible answers to them. The office of research management and international cooperation has conducted this research to suggest possible ways to facilitate the administrative support for the research activities of Korea Cancer Center Hospital By analyzing the change of research budget, organization of the division of research and administrative support, manpower, and the administrative research supporting system of other institutes, we suggested possible ways to enhance the work efficiency for administrative research support and developed a relative database program. The research report will serve as a data for the organization of research support division when the Radiation Medicine Research Center is established. The database program has already been used for research budget management

  18. Breast Cancer Research Training Grant

    Science.gov (United States)

    1997-10-01

    Pharmacology and Experimental Therapeutics Program in Research on Women-s Health Female Reproductive Aging : A Window into the Aging Brain Phyllis M. Wise...of luteinizing hormone-releasing hormone neuronal function. - PLEASE POST Phone: 638-4500 Department of B0Si PATHOLOGYI and Laboratory Medicine Boston...AT 1:00 SEPTEMBER 26 Jacob Sloane Brain inflammation in pathologic aging . Department of Pathology & Laboratory Medicine OCTOBER 3 Dr. Sun Tam The

  19. Flow Cytometry Scientist | Center for Cancer Research

    Science.gov (United States)

    The Basic Science Program (BSP) pursues independent, multidisciplinary research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics. Research efforts and support are an integral part of the Center for Cancer Research (CCR) at the Frederick National Laboratory for Cancer Research (FNLCR). KEY ROLES/RESPONSIBILITIES The Flow Cytometry Core (Flow Core) in the Cancer and Inflammation Program (CIP) is a service core which supports the research efforts of the CCR by providing expertise in the field of flow cytometry (fluorescence cell sorting) with the goal of gaining a more thorough understanding of the biology of the immune system, cancer, and inflammation processes. The Flow Core provides service to 12-15 CIP laboratories and more than 22 non-CIP laboratories. Flow core staff provide technical advice on the experimental design of applications, which include immunological phenotyping, cell function assays, and cell cycle analysis. Work is performed per customer requirements, and no independent research is involved. Flow Cytometry Scientist - The individual will be responsible for: Daily management of the Flow Cytometry Core, to include the supervision and guidance of technical staff members Monitor performance of and maintain high-dimensional flow cytometer analyzers and cell sorters Operate high-dimensional flow cytometer analyzers and cell sorters Provide scientific expertise to the user community and facilitate the development of cutting-edge technologies Interact with Flow Core users and customers, and provide technical and scientific advice, and guidance regarding their experiments, including possible collaborations Train staff and scientific end users on the use of flow cytometry in their research, as well as teach them how to operate and troubleshoot the bench-top analyzer instruments Prepare and deliver lectures, as well as one-on-one training sessions, with customers/users Ensure that protocols are up

  20. Individual Breast Cancer risk assessment in Underserved Populations: Integrating empirical Bioethics and Health Disparities Research

    Science.gov (United States)

    Anderson, Emily E.; Hoskins, Kent

    2013-01-01

    Research suggests that individual breast cancer risk assessment may improve adherence to recommended screening and prevention guidelines, thereby decreasing morbidity and mortality. Further research on the use of risk assessment models in underserved minority populations is critical to informing national public health efforts to eliminate breast cancer disparities. However, implementing individual breast cancer risk assessment in underserved patient populations raises particular ethical issues that require further examination. After reviewing these issues, we will discuss how empirical bioethics research can be integrated with health disparities research to inform the translation of research findings. Our in-progress National Cancer Institute (NCI) funded study, How Do Underserved Minority Women Think About Breast Cancer?, conducted in the context of a larger study on individual breast cancer risk assessment, is presented as a model. PMID:23124498

  1. Policy research institutions and the health SDGs: Building ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Institution. Sustainable Development Policy Institute. Pays d' institution. Pakistan. Site internet. http://www.sdpi.org ... du secteur de la sécurité en Asie du Sud. En Asie du Sud, le discours sur la sécurité a généralement eu cours dans les milieux gouvernementaux sans que les voix de la société civile s'y fassent entendre.

  2. The burden of disease of cancer in the Mexican Social Security Institute

    Directory of Open Access Journals (Sweden)

    Margot González-León

    2016-03-01

    Full Text Available Objective. To estimate the disease burden of cancer in theaffiliate population of the Mexican Social Security Institute (Instituto Mexicano del Seguro Social, IMSS in 2010 by delegation. Materials and methods. The Disability-Adjusted Life Years (DALYs, Years of Life Lost (YLL due to premature mortality and Years Lived with Disability/Disease (YLD for 21 specific cancers and a subgroup of other malignant neoplasms were calculated based on the methodology of the Global Burden of Disease Study (GBD for each of the 35 delegations of the IMSS. Results. In 2010, cancer represented the fifth overall leading cause of disease burden in IMSS affiliates (16.72 DALYs/1000 affiliates. A total of 75% of the cancer disease burden in each delegation is due to ten specific cancers, particularly breast cancer, which ranks first in 82% of the delegations. Prostate cancer; tracheal, bronchial, and lung cancers; leukemia, and colorectal and stomach cancers occupy the second to fourth positions in each delegation. With the exception of breast and prostate cancer, for which the contribution of YLD to the DALYs was higher than 50%, the greatest contribution to the DALYs of the other cancers was premature mortality, which accounted for more than 90% of the DALYs in some cases. Conclusion. The results obtained in this study allow for the identification of intervention priorities with regard to cancer at the institutional level and also for the focus at the delegation level to be placed on cancers ranking in the top positions for disease burden.

  3. Research advances at the Institute for Nutritional Sciences at Shanghai, China.

    Science.gov (United States)

    Chen, Yan; Lin, Xu; Liu, Yong; Xie, Dong; Fang, Jing; Le, Yingying; Ke, Zunji; Zhai, Qiwei; Wang, Hui; Guo, Feifan; Wang, Fudi; Liu, Yi

    2011-09-01

    Nutrition-related health issues have emerged as a major threat to public health since the rebirth of the economy in China starting in the 1980s. To meet this challenge, the Chinese Academy of Sciences established the Institute for Nutritional Sciences (INS) at Shanghai, China ≈ 8 y ago. The mission of the INS is to apply modern technologies and concepts in nutritional research to understand the molecular mechanism and provide means of intervention in the combat against nutrition-related diseases, including type 2 diabetes, metabolic syndrome, obesity, cardiovascular diseases, and many types of cancers. Through diligent and orchestrated efforts by INS scientists, graduate students, and research staff in the past few years, the INS has become the leading institution in China in the areas of basic nutritional research and metabolic regulation. Scientists at the INS have made important progress in many areas, including the characterization of genetic and nutritional properties of the Chinese population, metabolic control associated with nutrient sensing, molecular mechanisms underlying glucose and lipid metabolism, regulation of metabolism by adipokines and inflammatory pathways, disease intervention using functional foods or extracts of Chinese herbs, and many biological studies related to carcinogenesis. The INS will continue its efforts in understanding the optimal nutritional needs for Chinese people and the molecular causes associated with metabolic diseases, thus paving the way for effective and individualized intervention in the future. This review highlights the major research endeavors undertaken by INS scientists in recent years.

  4. Research Advances at the Institute for Nutritional Sciences at Shanghai, China12

    Science.gov (United States)

    Chen, Yan; Lin, Xu; Liu, Yong; Xie, Dong; Fang, Jing; Le, Yingying; Ke, Zunji; Zhai, Qiwei; Wang, Hui; Guo, Feifan; Wang, Fudi; Liu, Yi

    2011-01-01

    Nutrition-related health issues have emerged as a major threat to public health since the rebirth of the economy in China starting in the 1980s. To meet this challenge, the Chinese Academy of Sciences established the Institute for Nutritional Sciences (INS) at Shanghai, China ∼8 y ago. The mission of the INS is to apply modern technologies and concepts in nutritional research to understand the molecular mechanism and provide means of intervention in the combat against nutrition-related diseases, including type 2 diabetes, metabolic syndrome, obesity, cardiovascular diseases, and many types of cancers. Through diligent and orchestrated efforts by INS scientists, graduate students, and research staff in the past few years, the INS has become the leading institution in China in the areas of basic nutritional research and metabolic regulation. Scientists at the INS have made important progress in many areas, including the characterization of genetic and nutritional properties of the Chinese population, metabolic control associated with nutrient sensing, molecular mechanisms underlying glucose and lipid metabolism, regulation of metabolism by adipokines and inflammatory pathways, disease intervention using functional foods or extracts of Chinese herbs, and many biological studies related to carcinogenesis. The INS will continue its efforts in understanding the optimal nutritional needs for Chinese people and the molecular causes associated with metabolic diseases, thus paving the way for effective and individualized intervention in the future. This review highlights the major research endeavors undertaken by INS scientists in recent years. PMID:22332084

  5. 77 FR 35991 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-06-15

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special...., Scientific Review Officer, National Institute of Nursing Research, National Institutes of Health, Bethesda...

  6. 77 FR 6812 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-02-09

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, (301) 594-0343...

  7. 76 FR 5596 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2011-02-01

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial...: Weiqun Li, MD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  8. 76 FR 57068 - National Institute of Nursing Research Notice of Closed Meeting

    Science.gov (United States)

    2011-09-15

    ... Nursing Research Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Thyagarajan, PhD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  9. 75 FR 56118 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2010-09-15

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial...: Weiqun Li, MD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  10. 77 FR 3481 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-01-24

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial...: Weiqun Li, MD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  11. 76 FR 77240 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2011-12-12

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee... Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, (301) 594-0343, [email protected] . Name of Committee: National Institute of Nursing Research Special Emphasis...

  12. 77 FR 61418 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2012-10-09

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, (301) 594-0343...

  13. 76 FR 31621 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2011-06-01

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial...: Weiqun Li, MD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  14. 78 FR 2276 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-01-10

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... Institute of Nursing Research, National Institutes of Health, 6701 Democracy Blvd., Ste. 710, Bethesda, MD..., Nursing Research, National Institutes of Health, HHS) Dated: January 4, 2013. Michelle Trout, Program...

  15. 78 FR 63997 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-10-25

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special..., National Institute of Nursing Research, National Institutes of Health, 6701 Democracy Blvd., Suite 703K...

  16. 77 FR 27075 - National Institute of Nursing Research Notice of Closed Meeting

    Science.gov (United States)

    2012-05-08

    ... Nursing Research Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special... Thyagarajan, Ph.D., Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  17. 78 FR 73867 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-12-09

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special..., National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, 301-402-5807...

  18. 75 FR 1794 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2010-01-13

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special..., PhD, Scientific Review Officer, National Institute of Nursing Research, National Institutes of Health...

  19. 78 FR 17420 - National Institute of Nursing Research; Notice of Closed Meeting

    Science.gov (United States)

    2013-03-21

    ... Nursing Research; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act... unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Special..., Ph.D., Scientific Review Officer, National Institute of Nursing Research, National Institutes of...

  20. 75 FR 55808 - National Institute of Nursing Research; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-14

    ... Nursing Research; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee..., Scientific Review Administrator, National Institute of Nursing Research, National Institutes of Health, 6701...: National Institute of Nursing Research Special Emphasis Panel; Informed-Decision Making in Young Adolescent...