Sample records for cancer research english

  1. Research Learning on English

    Institute of Scientific and Technical Information of China (English)

    陈媛媛; 尹静; 岳艳岭


    The research learning is to select and define research topics, initiative to acquire knowledge, application of knowledge in research, problem-solving learning activities from nature, society and life. Research learning has been widely present in students life. Research study aims to develop the students' enthusiasm, initiative development of students' personality and so on, they all plays a crucial role for the right to develop a scientific attitude.

  2. Types of Cancer Research (United States)

    An infographic from the National Cancer Institute (NCI) describing the four broad categories of cancer research: basic research, clinical research, population-based research, and translational research.

  3. Breast Cancer Research Update (United States)

    ... JavaScript on. Feature: Breast Cancer Breast Cancer Research Update Winter 2017 Table of Contents National Cancer Institute ... Addressing Breast Cancer's Unequal Burden / Breast Cancer Research Update Winter 2017 Issue: Volume 11 Number 4 Page ...

  4. Chinese College English Teachers' Research Engagement (United States)

    Borg, Simon; Liu, Yi


    This mixed methods study adds to a growing international literature on the nature of language teachers' engagement with and in research by examining such engagement in the context of college English teaching in China. Questionnaire responses from 725 college English teachers and interviews with 20 of these teachers indicate that, although they…

  5. Primary School English Teachers' Research Engagement (United States)

    Gao, Xuesong; Chow, Alice Wai Kwan


    Research engagement is an important means for teachers to develop their professional competence. This paper reports on an enquiry into the research engagement of a group of primary school English language teachers in Guangdong province on the Chinese mainland. Drawing on questionnaire data and teachers' interview narratives, the paper examines how…

  6. Research methods for English language teachers

    CERN Document Server

    McDonough, Jo


    This book offers a lively introduction to the research methods and techniques available to English language teachers who wish to investigate aspects of their own practice. It covers qualitative and quantitative methodology and includes sections on observation, introspection, diary studies, experiments, interviews, questionnaires, numerical techniques and case study research. Each method is illustrated with examples in language teaching contexts, and techniques of data collection and analysis are introduced. The authors focus particularly on research in the classroom, on tests, materials, the

  7. Research on demand-oriented Business English learning method

    Directory of Open Access Journals (Sweden)

    Zhou Yuan


    Full Text Available Business English is integrated with visual-audio-oral English, which focuses on the application for English listening and speaking skills in common business occasions, and acquire business knowledge and improve skills through English. This paper analyzes the Business English Visual-audio-oral Course, and learning situation of higher vocational students’ learning objectives, interests, vocabulary, listening and speaking, and focuses on the research of effective methods to guide the higher vocational students to learn Business English Visual-audio-oral Course, master Business English knowledge, and improve communicative competence of Business English.

  8. Research in the Teaching of English (United States)

    Elley, Warwick B.


    Examines pertinent research findings that have appeared in the last half-century. Focus is on the role of grammar in an English syllabus, on the possibility of deliberately teaching the receptive skills of listening and reading, and on the impact of literature courses on students. References. (Author/RB)

  9. Suggestopedic/SALT research in English Literature

    Directory of Open Access Journals (Sweden)

    Jennifer Wilson


    Full Text Available This is a report of research. carried out under the auspices of the Institute for Language Teaching, University of Stellenbosch,l at the Cape Town College of Education. The study tests and evaluates a Remedial Literature Course for English-speaking college students using Suggestopedia!SALT. The subjects in _the remedial and normative groups were English-speaking students in the senior primary class. A ten-week suggestopedic!SALT English Literature Course was developed for the remedial course. Two measuring instruments were used: an English Literary Concepts Test and an Opinionnaire on attitudes towards EnglishLiterature. The validation, treatment and analysis oft he data are discussed. Conclusions and recommendations follow. Die verslag handel oor navorsing aan die Kaapstadse Onderwyskollege onder die beskerming van dielnstituutvir Taalonderrig van die UniversiteitvanStellenbosch.Die ondersoek toets en evalueer 'n remedierende letterkunde kursus vir Engelssprekende kollegestudente waar Suggestopedagogiek!SALT gebruik is. Die studente in die remedierende ennormatiewe groepe was Engelssprekend en in die senior-primere klas. 'n Suggestopediese!SALT Engelsletterkunde- kursus wat 10 weke sou duur, is vir die remedierende kursus ontwerp. Twee meetinstrumente is gebruik: 'n toets van Engels-literere konsepte en' n vraelys oor houdings ten opsigte van Engels-letterkunde. Die geldigverklaring. behandeling en ontleding van data word bespreek. Gevolgtrekkings en aanbevelings volg.

  10. A Reviewing on English Writing Researching in China

    Institute of Scientific and Technical Information of China (English)



    English writing is also a crucial means of evaluating the language proficiency of a learner of English as second language. As a result, it is essential to review English writing researching in terms of contents, number, methods, process, feedback and as⁃sessment which can guide our English writing teaching effectively.

  11. Action Research for English Teachers

    Institute of Scientific and Technical Information of China (English)



    As a reflective approach to teacher development,Action Research (AR)is gaining significance in education and is especially credited as providing an opportunity for professionals including both teachers and teacher educators to investigate their own classroom practice and improve it,and hopefully bring favorable changes to their classrooms.It emphasizes the role of critical reflection and always involves a problem→hypothesis→resolution cycle or spiral during which teacher researchers exert efforts to explore teaching and learning.By doing action research,language teachers can not only apply theories into practice but also be more reflective,more critical and more open to change in teach-ing approaches and methods.Despite the difficulties that teachers may have in doing action research in their busy life,it is beneficial for teach-ers to be researchers in the long run.

  12. English as a scientific and research language debates and discourses

    CERN Document Server

    Plo Alastrué, Ramón


    This volume examines the role of English in academic and research settings in Europe and provides recommendations on the challenges posed by the dominance of English over national languages as languages of science and research dissemination; the need for language support for academics that need to disseminate their research in English; and the effect of past and present language policies.

  13. Research on the Relationship between English Majors’ Learning Motivation and Spoken English in Chinese Context

    Institute of Scientific and Technical Information of China (English)



    With the increasing importance attached to spoken English, it is of great significance to find how the motivation of English majors affects their oral English learning outcomes. Based on the research results and theoretical frameworks of the previous studies on this area, this paper carries out research in Zhujiang College of South China Agricultural University trying to find out the types of motivation and the correlation between motivation factors of English majors and their spoken English, and thus to guide spoken English learning and teaching.

  14. Researches and Analysis on Middle School Students’ English Learning Motivation

    Institute of Scientific and Technical Information of China (English)

    陈虹; 韩小乐


    <正>This thesis discusses the relations among English learning motivations, learning strategies and study efficiency under China’s background through reviewing the Chinese and overseas English learning motivation research, analyzing its explanation, characteristics and the questionnaire results. Several suggestions on how to stimulate and foster the students’English learning motivation have been given through the analysis of existing problems in the English study of students. I expect these would be animating English teaching in school.

  15. Global cancer research initiative

    Directory of Open Access Journals (Sweden)

    Richard R Love


    Full Text Available Richard R LoveThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USAAbstract: Cancer is an increasing problem for low- and middle-income countries undergoing an epidemiologic transition from dominantly acute communicable disease to more frequent chronic disease with increased public health successes in the former domain. Progress against cancer in high-income countries has been modest and has come at enormous expense. There are several well-conceived global policy and planning initiatives which, with adequate political will, can favorably impact the growing global cancer challenges. Most financial resources for cancer, however, are spent on diagnosis and management of patients with disease in circumstances where specific knowledge about effective approaches is significantly limited, and the majority of interventions, other than surgery, are not cost-effective in resource-limited countries by global standards. In summary, how to intervene effectively on a global scale for the majority of citizens who develop cancer is poorly defined. In contrast to technology-transfer approaches, markedly increased clinical research activities are more likely to benefit cancer sufferers. In these contexts, a global cancer research initiative is proposed, and mechanisms for realizing such an effort are suggested.Keywords: breast cancer, research, global, international, low-income, middle-income

  16. Profiles in Cancer Research (United States)

    These articles put a face to some of the thousands of individuals who contribute to NCI’s cancer research efforts. The profiles highlight the work of scientists and clinicians and describe the circumstances and motivation behind their work.

  17. Bioprinting for cancer research. (United States)

    Knowlton, Stephanie; Onal, Sevgi; Yu, Chu Hsiang; Zhao, Jean J; Tasoglu, Savas


    Bioprinting offers the ability to create highly complex 3D architectures with living cells. This cutting-edge technique has significantly gained popularity and applicability in several fields. Bioprinting methods have been developed to effectively and rapidly pattern living cells, biological macromolecules, and biomaterials. These technologies hold great potential for applications in cancer research. Bioprinted cancer models represent a significant improvement over previous 2D models by mimicking 3D complexity and facilitating physiologically relevant cell-cell and cell-matrix interactions. Here we review bioprinting methods based on inkjet, microextrusion, and laser technologies and compare 3D cancer models with 2D cancer models. We discuss bioprinted models that mimic the tumor microenvironment, providing a platform for deeper understanding of cancer pathology, anticancer drug screening, and cancer treatment development.

  18. A Research of Schema Theory in English Listening Teaching

    Institute of Scientific and Technical Information of China (English)



    Nowadays, English listening is playing a more and more important role in English teaching. And the research of listening is becoming the key point. The Schema Theory, based on the cognitive psychology, is becoming a new way in English teaching. It is a reform to the traditional listening teaching, which can give full play to students’ initiative. This paper wil make a study on the Schema Theory used in English Listening Teaching.

  19. Primary School English Teachers'Research Engagement%Primary School English Teachers'Research Engagement

    Institute of Scientific and Technical Information of China (English)

    Xuesong Gao; Alice Wai Kwan Chow


    Research engagement is an important means for teachers to develop their professional competence. This paper reports on an enquiry into the research engagement of a group of primary school English language teachers in Guangdong province on the Chinese mainland. Drawing on questionnaire data and teachers' interview narratives, the paper examines how these Chinese primary school teachers experienced research and what their conceptions of good quality research were. While the enquiry revealed that the participants had a variety of research experiences, it also revealed that their

  20. Research and Exploration of College English Teaching

    Institute of Scientific and Technical Information of China (English)



    College English teaching reform has been one of the hot issues of higher education.The reform of college English teaching in recent years has made some achievements,but still there are many problems.This paper mainly focus on the following questions: What are the problems in college English teaching. The corresponding measures are proposed in this paper to address these issues.

  1. Investigating Generic Structure of English Research Articles: Writing Strategy Differences between English and Indonesian Writers

    Directory of Open Access Journals (Sweden)

    Ni Ketut Mirahayuni


    Full Text Available Abstract. Research into English research articles (RAs has largely been focused on articles produced by native English writers. This paper reports a study aiming to investigate the textual structure of research articles written by non-native English (i.e. Indonesian writers, which may contribute to their acceptance for international publication. A comparison is made between RAs written by native English speakers, an Indonesian writers writing in English, all in the field of Language and Language Teaching. It explores the relation of text's generic structure. The thesis develops a framework for the generic structure analysis based on Swales' (1990 Create-A­Research-Space (CARS model of moves. The analysis focuses on two RA sections: Introduction and Discussion. The findings indicate significant differences in both forms and functions of organizing strategics between the native and non-native texts. The differences may partly be due to the influence of writing practices in the non-native writers' first language and partly to the writer's attempt to find an appropriate format in the absence of well-established research writing conventions in the first language. Consequently, non-native English texts may show organizing strategies unfamiliar to both the native English and native Indonesian texts. Findings from the research highlight two issues. First, formal and functional differences of generic structure elements and their realizations between the native and non-native English texts may disadvantage the non-native writers, particularly with regards to employment of unfamiliar organizational

  2. Experimental research on English vowel errors analysis

    Directory of Open Access Journals (Sweden)

    Huang Qiuhua


    Full Text Available Our paper analyzed relevant acoustic parameters of people’s speech samples and the results that compared with English standard pronunciation with methods of experimental phonetics by phonetic analysis software and statistical analysis software. Then we summarized phonetic pronunciation errors of college students through the analysis of English pronunciation of vowels, we found that college students’ English pronunciation are easy occur tongue position and lip shape errors during pronounce vowels. Based on analysis of pronunciation errors, we put forward targeted voice training for college students’ English pronunciation, eventually increased the students learning interest, and improved the teaching of English phonetics.

  3. nvestigating Generic Structure of English Research Articles: Writing Strategy Differences between English and Indonesian Writers

    Directory of Open Access Journals (Sweden)

    Ni Ketut Mirahayuni


    Full Text Available Research into English research articles (RAs has largely been focused on articles produced by native English writers. This paper reports a study aiming to investigate the textual structure of research articles written by non-native English (i.e. Indonesian writers, which may contribute to their acceptance for international publication. A comparison is made between RAs written by native English speakers, an Indonesian writers writing in English, all in the field of Language and Language Teaching. It explores the relation of text's generic structure. The thesis develops a framework for the generic structure analysis based on Swales' (1990 Create-A-Research-Space (CARS model of moves. The analysis focuses on two RA sections: Introduction and Discussion. The findings indicate significant differences in both forms and functions of organizing strategies between the native and non-native texts. The differences may partly be due to the influence of writing practices in the non-native writers' first language and partly to the writer's attempt to find an appropriate format in the absence of well-established research writing conventions in the first language. Consequently, non-native English texts may show organizing strategies unfamiliar to both the native English and native Indonesian texts. Findings from the research highlight two issues. First, formal and functional differences of generic structure elements and their realizations between the native and non-native English texts may disadvantage the non-native writers, particularly with regards to employment of unfamiliar organizational strategies. Second, non-native English writers need to acquire knowledge of commonly used formal generic structure, and more importantly, the knowledge of the nature of scientific writing in English to be able to gain wider readership. The implications for further research and the teaching of academic writing are discussed.

  4. Research and Exploration of College English Teaching

    Institute of Scientific and Technical Information of China (English)



    College English teaching reform has been one of the hot issues of higher education.The reform of college English teaching in recent years has made some achievements,but still there are many problems.This paper mainly focus on the following questions: What are the problems in college English teaching.The corresponding measures are proposed in this paper to address these issues.

  5. Fostering Cooperation in Cancer Research (United States)

    Thursday, June 25, 2015 Memorandum of Understanding (MoU) was signed between US National Cancer Institute and three agencies of the Indian government - the Department of Biotechnology, the Indian Council of Medical Research, and the Indian National Cancer Institute, a part of the All India Institute of Medical Sciences to foster cooperation in cancer research.

  6. English-Language Teachers' Engagement with Research: Findings from Bangladesh (United States)

    Anwaruddin, Sardar M.; Pervin, Nasrin


    In this article, we report on a small-scale study in which we investigated English-language teachers' engagement with educational research. We conceptualized engagement with research as reading and systematically using research for professional development. Using questionnaires and in-depth interviews, we gathered empirical materials from 40…

  7. Trends in Doctoral Research on English Language Teaching in Turkey (United States)

    Özmen, Kemal Sinan; Cephe, Pasa Tevfik; Kinik, Betül


    This review examines the doctoral research in Turkey completed between 2010 and 2014 in the area of English language teaching and learning. All of the dissertations (N = 137) indexed in the National Theses Database have been included in order to analyze dissertations' subject areas, research paradigms/techniques, and research contexts as well as…

  8. Research in Danish cancer rehabilitation

    DEFF Research Database (Denmark)

    Høybye, Mette Terp; Dalton, Susanne Oksbjerg; Christensen, Jane


    of the cancer survivors with respect to cancer site, sociodemographic variables, social network, lifestyle, self-rated health and the prevalence of cancer-related late effects. The study is part of the FOCARE research project, in which the long-term effects of the rehabilitation programme are evaluated...

  9. Basic research in kidney cancer

    NARCIS (Netherlands)

    Oosterwijk, E.; Rathmell, W.K.; Junker, K.; Brannon, A.R.; Pouliot, F.; Finley, D.S.; Mulders, P.F.A.; Kirkali, Z.; Uemura, H.; Belldegrun, A.


    CONTEXT: Advances in basic research will enhance prognosis, diagnosis, and treatment of renal cancer patients. OBJECTIVE: To discuss advances in our understanding of the molecular basis of renal cancer, targeted therapies, renal cancer and immunity, and genetic factors and renal cell carcinoma (RCC)

  10. Research Article Introductions in English for Specific Purposes: A Comparison between Brazilian Portuguese and English (United States)

    Hirano, Eliana


    This paper compares the rhetorical organization of research article introductions in Brazilian Portuguese and in English within a subfield of Applied Linguistics. Using Swales' (1990) CARS model as an analytical tool, this exploratory study investigated 20 research articles. The findings indicate that introductions in Brazilian Portuguese tend to…

  11. Current concepts in cancer research

    Directory of Open Access Journals (Sweden)

    Ivan Kok Seng Yap


    Full Text Available Cancer research is an extremely broadtopic covering many scientific disciplines includingbiology (e.g. biochemistry and signal transduction,chemistry (e.g. drug discover and development,physics (e.g. diagnostic devices and even computerscience (e.g. bioinformatics. Some would argue thatcancer research will continue in much the same wayas it is by adding further layers of complexity to thescientific knowledge that is already complex and almostbeyond measure. But we anticipate that cancer researchwill undergo a dramatic paradigm shift due to therecent explosion of new discoveries in cancer biology.This review article focuses on the latest horizons incancer research concerning cancer epigenetics, cancerstem cells, cancer immunology and cancer metabolism.

  12. Nebraska Prostate Cancer Research Program (United States)


    2011.  LaTayia Aaron and Joann Powell. (2012). Dioxin exposure enhances nuclear localization of androgen be trained in different areas of prostate cancer research. For example, the focus areas or research include Biomarkers , Therapy, Genetics, and...example, the focus areas or research include Biomarkers , Therapy, Genetics, and Tumor Biology as outlined by the laboratory research descriptions in the

  13. American Institute for Cancer Research (United States)

    ... About Cancer By Cancer Site What Is Cancer Foods That Fight Cancer Tools You Can Use Cancer Infographics & Multimedia Studying ... About Cancer By Cancer Site What Is Cancer Foods That Fight Cancer Tools You Can Use Cancer Infographics & Multimedia Studying ...

  14. Cancer immunoinformatics: a new assistant tool for malignant disease research

    Institute of Scientific and Technical Information of China (English)

    Wang Weijia; Zhang Rupeng; Liang Han; Zhang Hui; Li Fangxuan; Yu Jinpu; Li Hui


    Objective To introduce the recent developments in cancer immunoinformatics with an emphasis on the latest trends and future direction.Data sources All related articles in this review were searched from PubMed published in English from 1992 to 2013.The search terms were cancer,immunoinformatics,immunological databases,and computational vaccinology.Study selection Original articles and reviews those were related to application of cancer immunoinformatics about tumor basic and clinical research were selected.Results Cancer immunoinformatics has been widely researched and applied in a series of fields of cancer research,including computational tools for cancer,cancer immunological databases,computational vaccinology,and cancer diagnostic workflows.Furthermore,the improvement of its theory and technology brings an enlightening insight into understanding and researching cancer and helps expound more deep and complete mechanisms of tumorigenesis and progression.Conclusion Cancer immunoinformatics provides promising methods and novel strategies for the discovery and development of tumor basic and clinical research.

  15. Annotated bibliography of research in the teaching of English



    This bibliography includes abstracts of selected empirical research studies as well as titles of other related studies and books published between June 2013 and May 2014. Abstracts are only written for research studies that employed systematic analysis of phenomena using experimental, qualitative, ethnographic, discourse analysis, literary critical, content analysis, or linguistic analysis methods. Priority is given to research most directly related to the teaching of English language arts. C...

  16. What's New in Thyroid Cancer Research and Treatment? (United States)

    ... Thyroid Cancer About Thyroid Cancer What’s New in Thyroid Cancer Research and Treatment? Important research into thyroid cancer ... in Thyroid Cancer Research and Treatment? More In Thyroid Cancer About Thyroid Cancer Causes, Risk Factors, and Prevention ...

  17. What's New in Testicular Cancer Research and Treatment? (United States)

    ... Testicular Cancer About Testicular Cancer What’s New in Testicular Cancer Research and Treatment? Important research into testicular cancer ... in Testicular Cancer Research and Treatment? More In Testicular Cancer About Testicular Cancer Causes, Risk Factors, and Prevention ...

  18. Prostate Cancer Research Training Program (United States)


    evaluate medication safety. Examples of HERCe research include recent publications on breast cancer treatments, complications of chemotherapy for...with specific interest in minimally invasive procedures, new techniques, and outcomes. Dr. Brown initiated many of the laparoscopic and robotic ... surgery as it is one of the main areas of his clinical expertise. Currently, he performs more prostate cancer surgery than any other physician in

  19. Annotated Bibliography of Research in the Teaching of English (United States)

    Beach, Richard; Bigelow, Martha; Dillon, Deborah; Galda, Lee; Helman, Lori; Kalnin, Julie Shalhope; Lewis, Cynthia; O'Brien, David; Jorgensen, Karen; Liang, Lauren; Rijlaarsdam, Gert; Janssen, Tanja


    This annotated bibliography of Research in the Teaching of English addresses the following topics: (1) Discourse/Narrative Analysis/Cultural Difference; (2) Literacy; (3) Literary Response/Literature; (4) Reading; (5) Professional Development/Teacher Education; (6) Second Language Literacy; (7) Technology/Media; and (8) Writing.

  20. Annotated Bibliography of Research in the Teaching of English (United States)

    Beach, Richard; Brendler, Beth; Dillon, Deborah; Dockter, Jessie; Ernst, Stacy; Frederick, Amy; Galda, Lee; Helman, Lori; Kapoor, Richa; Ngo, Bic; O'Brien, David; Scharber, Cassie; Jorgensen, Karen; Liang, Lauren; Braaksma, Martine; Janssen, Tanja


    This article presents an annotated bibliography of "Research in the Teaching of English" (RTE). The 2010 version of the bibliography involves a major change--the bibliography is available solely as a downloadable pdf file at As the length of the bibliography has grown from 15 pages in 2003 to 88 pages…

  1. An English Professor's Pentacle: How Research Completes the "Endless Knot." (United States)

    Campbell, Jeff H.


    An English professor explains how his own involvement in an ongoing research project has affected and improved each of the five aspects of his job: instruction in composition, imparting enthusiasm to nonmajors, providing sound and thorough instruction to majors, assisting graduate students in specialized projects, and noninstructional professional…

  2. Annotated bibliography of research in the teaching of English

    NARCIS (Netherlands)

    Beach, R.; Bigelow, M.; Dillon, D.; Dockter, J.; Galda, L.; Helman, L.; Kapoor, R.; Ngo, B.; O'Brien, D.; Sato, M.; Scharber, C.; Jorgensen, K.; Liang, L.; Braaksma, M.; Janssen, T.


    The committee reviews important research works in the teaching of English that have been published in the last year. Committee members include Richard Beach, Martha Bigelow, Martine Braaksma, Deborah Dillon, Jessie Dockter, Lee Galda, Lori Helman, Tanja Janssen, Karen Jorgensen, Richa Kapoor, Lauren

  3. Research on English Teaching and Learning: Taiwan (2004-2009) (United States)

    Chen, Suchiao; Tsai, Yachin


    This article analyzes research in second/foreign language teaching and learning conducted in Taiwan over the period 2004-2009. Representative articles published in local refereed journals and conference proceedings--not readily accessible outside Taiwan--are reviewed to reflect current trends in English teaching and learning. The main themes…

  4. Hedging and Boosting in English and Indonesian Research Articles (United States)

    Sanjaya, I Nyoman Suka


    The present cross-cultural and cross-disciplinary study was aimed at exploring the similarities and differences between English and Indonesian research articles from the disciplines of applied linguistics and chemistry in terms of frequency of usage of hedges (e.g. "perhaps," "may") and boosters (e.g. "clearly,"…

  5. Mouse models for cancer research

    Institute of Scientific and Technical Information of China (English)

    Wei Zhang; Lynette Moore; Ping Ji


    Mouse models of cancer enable researchers to leamn about tumor biology in complicated and dynamic physiological systems. Since the development of gene targeting in mice, cancer biologists have been among the most frequent users of transgenic mouse models, which have dramatically increased knowledge about how cancers form and grow. The Chinese Joumnal of Cancer will publish a series of papers reporting the use of mouse models in studying genetic events in cancer cases. This editorial is an overview of the development and applications of mouse models of cancer and directs the reader to upcoming papers describing the use of these models to be published in coming issues, beginning with three articles in the current issue.

  6. Researching Contradictions: Cultural Historical Activity Theory Research (CHAT) in the English Classroom (United States)

    Thompson, Ian


    This article argues that Cultural Historical Activity Theory (CHAT) is an appropriate theoretical and methodological framework for researchers in English interested in the social contexts of culture and its relationship with the formation of mind and activity in the English classroom. Two key concepts in Vygotsky's thought central to understanding…

  7. Nebraska Prostate Cancer Research Program (United States)


    Annual National Symposium on Prostate Cancer by CCRTD, CAU, March 16-19, 2014. 15. Appendix #15: Peer- reviewed scientific publication with inputs...and  Immunology Y. Tu CU Regulation of G‐Protein‐Coupled  Receptors in Prostate  Cancer     Acknowledgements: DOD CDMRP PCa Research Program PC121645...AWARD NUMBER: W81XWH-13-1-0264 TITLE: Nebraska Prostate Cancer Research Program PRINCIPAL INVESTIGATOR: Ming-Fong Lin, Ph.D

  8. An analysis of research in english for academic purposes


    Pehlivan, Elif


    Cataloged from PDF version of article. Thesis (M.S.): Bilkent University, The Program of Curriculum and Instruction, İhsan Doğramacı Bilkent University, 2016. Includes bibliographical references (leaves 74-116). This study reports written content analysis results of published research in the field of English for Academic Purposes. The research questions of this study are: What are the most common journal article types published in the field of EAP? What are the most common topics cov...

  9. Research Article Introductions in Chinese and English: A Comparative Genre-Based Study (United States)

    Loi, Chek Kim


    This study investigates the rhetorical organisation of English and Chinese research article introductions in the field of educational psychology using (Swales, 1990) and (Swales, 2004) framework of move analysis. A corpus of 40 research articles (20 Chinese and 20 English) was selected. The English research articles, written by first-language…

  10. Breast Cancer Research Program (United States)


    tion of tumor cells with red indicating the highest density of tumor cells at the primary tumor (4th mammary fat pad ) and purple/blue showing the...Idea Award Elaine Hardman and Philippe Georgel “ Maternal Consumption of Omega 3 Fatty Acids to Reduce Breast Cancer Risk in Offspring” FY09

  11. Uterine Cancer Statistics (United States)

    ... Research AMIGAS Fighting Cervical Cancer Worldwide Stay Informed Statistics for Other Kinds of Cancer Breast Cervical Colorectal ( ... Skin Vaginal and Vulvar Cancer Home Uterine Cancer Statistics Language: English Español (Spanish) Recommend on Facebook Tweet ...

  12. Research on the Business English training model within MBA program


    Natalia Yankovskaya; Olga Neklyudova


    The paper presents a brief summary of the research on the Business English training model within MBA program students. This study is devoted to the problem of developing a professional foreign language communicative competency of MBA program participants. A particular feature of additional MBA qualification is its international status which presupposes that its graduates (mid-level and top managers) should realize their professional tasks in a foreign language. The analysis of literary ...

  13. The Research on English News Translation

    Institute of Scientific and Technical Information of China (English)



    With the development of the whole world, news has become an essential part in our daily life. Therefore, it is very necessary to do some research on news. In view of the distinctive features of news itself and cultural differences between the West and the East, the thesis tries to discuss that to convey an accurate translation Nida ’s functional equivalence theory can be applied to compare the accuracy between the source language and the target language. A brief introduction of this theory is given at the beginning. The author puts more efforts to investigate how the theory is feasible to guide the news translation at lexical level in the next section.

  14. Investigating Vocabulary and Reading Strategies with Middle Grades English Language Learners: A Research Synthesis (United States)

    Cisco, Brooke Kandel; Padron, Yolanda


    Recent data indicate that many adolescent English language learners (ELLs) comprehend English texts at only a limited literal level. The purpose of this research synthesis was to systematically identify and describe the research related to the English reading comprehension of middle grades ELLs while also making practical connections to…

  15. English

    CERN Document Server

    Nelson, Gerald


    "English: An Essential Grammar" is a concise and user-friendly guide to the grammar of modern English, written specifically for native speakers and based on genuine samples of contemporary spoken and written English. In four chapters, the book covers the essentials of English grammar, beginning with the basics and going on to deal with phrase, clause and sentence structure. A fifth chapter deals with English word formation and spelling, including problem spellings and British and American spelling variants. Features of this title include: discussion of points that often cause problem

  16. Development and reform research of English teaching theory and practice

    Institute of Scientific and Technical Information of China (English)

    Jie Guo


    The course is the core of education, which is the basic way to achieve educational goals, an educational content and value orientation are mainly expressed and implemented through the curriculum. English courses are the core of English education, which is a concrete manifestation of the value of English education, and it is basic carrier to achieve the goal of English education. This paper analyzes the development of English teaching practice, development and reform of English teaching methods.

  17. What's New in Liver Cancer Research and Treatment? (United States)

    ... Liver Cancer About Liver Cancer What's New in Liver Cancer Research and Treatment? Because there are only a ... in Liver Cancer Research and Treatment? More In Liver Cancer About Liver Cancer Causes, Risk Factors, and Prevention ...

  18. What's New in Ovarian Cancer Research and Treatment? (United States)

    ... Ovarian Cancer About Ovarian Cancer What's New in Ovarian Cancer Research and Treatment? Risk factors and causes Scientists ... in Ovarian Cancer Research and Treatment? More In Ovarian Cancer About Ovarian Cancer Causes, Risk Factors, and Prevention ...

  19. Gene-Environment Research and Cancer Epidemiology (United States)

    The Epidemiology and Genomics Research Program supports extramural research that investigates both genetic and environmental factors that may contribute to the etiology of cancer and/or impact cancer outcomes.

  20. Center for Herbal Research on Colorectal Cancer (United States)

    Federal Laboratory Consortium — Research Area: Herbs Program:Centers of Excellence for Research on CAM Description:Colorectal cancer is the third most common cancer and the third leading cause of...

  1. Frederick National Laboratory for Cancer Research (United States)

    Federal Laboratory Consortium — Among the many cancer research laboratories operated by NCI, the Frederick National Laboratory for Cancer Research(FNLCR) is unique in that it is a Federally Funded...

  2. What's New in Research and Treatment for Thymus Cancer? (United States)

    ... Cancer What’s New in Research and Treatment for Thymus Cancer? There is always research going on in ... Research and Treatment for Thymus Cancer? More In Thymus Cancer About Thymus Cancer Causes, Risk Factors, and ...

  3. English version: Research education for diversity in educational research

    Directory of Open Access Journals (Sweden)

    Andrew Brown


    Full Text Available Concern expressed by government and other funding agencies and consumers of research, about the quality and relevance of research in the field of education affects not only the kind of research is conducted but also the way in which we educate researchers. The economic imperative for ‘value for money’ from research and researchers has, for instance, led to the education of research students to be seen increasingly in terms of training in a range of generic skills that can be applied to the investigation of a range of forms of research problem in a variety of contexts. Whilst breadth in the education of researchers has clear advantages, both for the careers of individual researchers and the wider research community, there is some tension between this approach and the more established view of a research degree as an induction into a narrow domain of knowledge and the production of a highly specialised academic identity. There are further developments that erode this notion of specialisation, for instance the growth of mixed method research, which has the potential to challenge the polarisation of qualitative and quantitative research, and shifts in the sites and agents of educational research signified by the growth of professional doctorates, which could further challenge the university as a dominant institution in the production of educational knowledge. In this paper I will explore what these developments mean for the teaching of research and consider how we can work collaboratively to develop both professional researchers and researching professionals, and reconcile the acquisition of skills with induction into specialised knowledge domains. This will involve exploration of both an overarching framework for thinking about the processes of doing research and specific examples of practice. Underlying the approach taken is a general commitment to research education, rather than to training and the teaching of methods, and the desire to ensure

  4. Research on Demand Analysis of the Users of the Senior English Diagnostic System (United States)

    Guo, Chen; Zhang, Hui; Yao, Qian; Wu, Min


    As the significance of learning English is becoming increasingly apparent, more and more English online practice systems are used by English learners. However, a thorough process of research and detailed analysis of user demand have not fully implemented before the design of these systems. As a result, these systems may suffer the defects of low…

  5. A Research on Reading Strategies among Non-English Major Postgraduates (United States)

    Yang, Yang


    As a very important skill both in English teaching and learning, reading strategy has been emphasized at home and abroad for a long time. Many scholars and teachers make research on undergraduates of English major or non-English major. However, the postgraduates are often neglected. Actually, it is also imperative to make a study among…

  6. Research-Based Vocabulary Instruction for English Language Learners (United States)

    Chung, Stephanie F.


    A major reading-achievement gap exists between English language learners and English-only students. In order for ELLs to experience school success, they must achieve English language proficiency. This article presents why vocabulary acquisition plays the most vital role in ELLs' learning of the English language. Factors include the severity and…

  7. The Research of College Students’English Classroom Behavior Investigations

    Institute of Scientific and Technical Information of China (English)



    By employing quantitative research methods, the paper investigates college students ’preferences to English classroom behaviors and the relations between behaviors and achievements. The results indicate that there are significant differences among the subjects’behavior, cognitive and emotional elements, and their classroom behaviors are mainly visual, individual, imitative and exterior-motivated;there are significant differences in behavior element and emotional element between high-result group and low-result group;confident and oral classroom behaviors have prominent relations with CET-4 achievements, and different teaching methods may make learning behaviors produce good or bad effects to achievements.

  8. Drosophila models for cancer research. (United States)

    Vidal, Marcos; Cagan, Ross L


    Drosophila is a model system for cancer research. Investigation with fruit flies has facilitated a number of important recent discoveries in the field: the hippo signaling pathway, which coordinates cell proliferation and death to achieve normal tissue size; 'social' behaviors of cells, including cell competition and apoptosis-induced compensatory proliferation, that help ensure normal tissue size; and a growing understanding of how oncogenes and tumor suppressors cooperate to achieve tumor growth and metastasis in situ. In the future, Drosophila models can be extended beyond basic research in the search for human therapeutics.

  9. Interdisciplinary Research Training in Breast Cancer (United States)


    University. An Internet-Based Low- Literacy Cancer Communication Intervention. $1,500, funded. * 2004- Pfizer Clear Health Communication Program. An...Internet-Based Low- Literacy Cancer Communication Intervention. $195,000, not funded. 0 2004- DOD Breast Cancer Research Program, Multidisciplinary...of Connecticut and Yale University. While providing didactic experience in advanced research, methodology, it allows the candidate to have sustained

  10. Learners' Beliefs about Learning English:Action Research


    鈴木, 栄


    This paper reports on beliefs SIT students hold regarding English learning. Their beliefs were elicited via discursive approach by investigating metaphors they used in a questionnaire. Metaphors are supported to reflect students' beliefs about their experiences of learning English. By classifying and examining their metaphors, what students think about learning English can be revealed. The paper also describes implementations of English Literacy I, which were designed based the findings of th...

  11. Prostate cancer research in China

    Institute of Scientific and Technical Information of China (English)

    Shan-Cheng Ren; Rui Chen; Ying-Hao Sun


    Prostate cancer (PCa) research in China has been on a rocketing trend in recent years.The first genome-wide association study (GWAS)in China identified two new PCa risk associated single nucleotide polymorphisms (SNPs).Next generation sequencing is beginning to be used,yielding novel findings:gene fusions,long non-coding RNAs and other variations.Mechanisms of PCa progression have been illustrated while various diagnosis biomarkers have been investigated extensively.Personalized therapy based on genetic factors,nano-medicine and traditional Chinese medicine has been the focus of experimental therapeutic research for PCa.This review intends to shed light upon the recent progress in PCa research in China and points out the possible breakthroughs in the future.

  12. Breast Cancer and the Environment Research Program (United States)

    The Breast Cancer and the Environment Research Program supports a multidisciplinary network of scientists, clinicians, and community partners to examine the effects of environmental exposures that may predispose a woman to breast cancer throughout her life.

  13. Developing Investigative Entry Points: Exploring the Use of Quantitative Methods in English Education Research (United States)

    McGraner, Kristin L.; Robbins, Daniel


    Although many research questions in English education demand the use of qualitative methods, this paper will briefly explore how English education researchers and doctoral students may use statistics and quantitative methods to inform, complement, and/or deepen their inquiries. First, the authors will provide a general overview of the survey areas…

  14. Enablers and Inhibitors to English Language Learners' Research Process in a High School Setting (United States)

    Kim, Sung Un


    This researcher sought to examine enablers and inhibitors to English language learner (ELL) students' research process within the framework of Carol C. Kuhlthau's Information Search Process (ISP). At a high school forty-eight ELL students in three classes, an English as a Second Language (ESL) teacher, and a biology teacher participated in the…

  15. English Language Teaching Research in South Korea: A Review of Recent Studies (2009-2014) (United States)

    Moodie, Ian; Nam, Hyun-Jeong


    This article reviews recent studies on English language teaching (ELT) in South Korea, where a great deal of research has been produced in recent years in local journals. In this article we review 95 studies from a pool of some 1,200 published between 2009 and 2014 on English language teaching and learning, focusing on research within the public…

  16. English

    DEFF Research Database (Denmark)

    Phillipson, Robert


    The article exemplifies and presents the characteristics of linguistic imperialism, linguistic capital accumulation following the same pattern as capitalist economic dominance. The text summarizes the way English was established in the colonial period. Many of the mechanisms of linguistic hierarchy...... have been maintained and intensified since then, as African and Indian scholarship demonstrates. Language plays a key role in education, the World Bank taking over where colonial regimes left off. Anglo-American efforts to maintain global English dominance have intensified since 1945 and are central...... to the present-day world ‘order’, as the postcolonial is subsumed under global empire, assisted by English linguistic neoimperialism. Some scholars who deny the existence of linguistic imperialism are reported on, and the complexity of language policy in European integration is demonstrated. The article...

  17. Get the metaphor right! Cancer treatment metaphors in the English and Spanish press


    Williams Camus, Julia T.


    This study explores the use of metaphor in the presentation of cancer therapies in a corpus of 300 popularisation articles in four quality newspapers, The Guardian, The Times, El País and El Mundo, in the English and Spanish press. More specifically, it seeks to investigate the ways in which currently available cancer treatments are portrayed as opposed to those still under development. Metaphorically used words were identified primarily according to the ‗Metaphor Identification Procedure‘ MI...

  18. Research on effective teaching methods of higher vocational English

    Institute of Scientific and Technical Information of China (English)



    With the rapid development of our country's education, the progress of English teaching in higher vocational colleges is gradually developed. Effective teaching become an important teaching concept and goal of all school courses. This article, analyzes the present situation of English teaching in higher vocational colleges, and points out that the shortcomings in the process of higher vocational English(HVE) teaching. Finally, attempt to explore some effective strategies to improve the quality of HVE teaching.

  19. Lysyl oxidase in cancer research. (United States)

    Perryman, Lara; Erler, Janine T


    Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target. In this review we will breakdown the process of cancer progression and the various roles that LOX plays has in the advancement of cancer. We will highlight why LOX is an exciting therapeutic target for the future.

  20. Basic research on cancer related to radiation associated medical researches

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong In; Hwang, Dae Yong; Bang, Ho Yoon [and others


    Basic Research on Cancer related to Radiation Associated Medical Researches including 1. Establishment of animal model of colorectal cancer liver metastasis and measurement of angiogenesis, 2. Tissue expression of Tie-1 and Tie-2 in human colorectal cancer, 3. Enhancement of G2/Mphase Cell Fraction by Adenovirus-mediated p53 Gene Transfer in Ovarian Cancer Cell Lines, 4. Clinical Characteristics of the patients with Non-B Non-C Hepatocellular Carcinoma and Frequency of HBV, HCV and TTV Viremia in these Patients, 5. Significance of serum iron and ferritin in patients with stomach cancer, 6. Telomerase assay for early detection of lung cancer, 7. Study on the Usefulness of Aldehyde dehydrogenase-2 Genotyping for Risk Group of Alcohol-related Cancer Screening, 8. Gene therapy using hepatoma specific promoter, 9. Study on the Influence of DNA repair gene, XRCC1 Genotypes on the Risk of Head and Neck Cancer were performed.

  1. Novel translational strategies in colorectal cancer research

    Institute of Scientific and Technical Information of China (English)


    Defining translational research is still a complex task. In oncology, translational research implies using our basic knowledge learnt from in vitro and in vivo experiments to directly improve diagnostic tools and therapeutic approaches in cancer patients. Moreover, the better understanding of human cancer and its use to design more reliable tumor models and more accurate experimental systems also has to be considered a good example of translational research. The identification and characterization of new molecular markers and the discovery of novel targeted therapies are two main goals in colorectal cancer translational research. However, the straightforward translation of basic research findings, specifically into colorectal cancer treatment and vice versa is still underway. In the present paper, a summarized view of some of the new available approaches on colorectal cancer translational research is provided. Pros and cons are discussed for every approach exposed.

  2. Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention (United States)

    The Nutritional Science Research Group in the Division of Cancer Prevention at the National Cancer Institute, National Institutes of Health and the Department of Nutrition at the Clinical Center, National Institutes of Health are offering a one week educational opportunity in "Nutrition and Cancer Prevention Research" for individuals with a sustained commitment to nutrition and health promotion. This one-week intense learning session provides specialized instruction in the role of diet and bioactive food components as modifiers of cancer incidence and tumor behavior. |

  3. Research and comprehensive cancer control coalitions. (United States)

    Vinson, Cynthia; La Porta, Madeline; Todd, William; Palafox, Neal A; Wilson, Katherine M; Fairley, Temeika


    The goal of cancer control research is "to generate basic knowledge about how to monitor and change individual and collective behavior and to ensure that knowledge is translated into practice and policy rapidly, effectively, and efficiently" (Division of Cancer Control and Population Sciences in Cancer control framework and synthese rationale, 2010). Research activities span the cancer control continuum from prevention to early detection and diagnosis through treatment and survivorship (Division of Cancer Control and Population Sciences in Cancer control framework and synthese rationale, 2010). While significant advancements have been made in understanding, preventing and treating cancer in the past few decades, these benefits have yielded disproportionate results in cancer morbidity and mortality across various socioeconomic and racial/ethnic subgroups (Ozols et al in J Clin Oncol, 25(1):146-1622, 2007). It has been a high priority since the beginning of the Comprehensive Cancer Control (CCC) movement to utilize research in the development and implementation of cancer plans in the states, tribes and tribal organizations, territories and US Pacific Island Jurisdictions. Nevertheless, dissemination and implementation of research in coalition activities has been challenging for many programs. Lessons learned from programs and coalitions in the implementation and evaluation of CCC activities, as well as resources provided by national partners, can assist coalitions with the translation of research into practice.

  4. Genomic Datasets for Cancer Research (United States)

    A variety of datasets from genome-wide association studies of cancer and other genotype-phenotype studies, including sequencing and molecular diagnostic assays, are available to approved investigators through the Extramural National Cancer Institute Data Access Committee.

  5. Research on the Mistakes Made by College English Teachers in Pronunciation of/n/&/l

    Institute of Scientific and Technical Information of China (English)

    刘斌; 桂严捷


    As an old saying goes that“once you open mouth, you are decided”. Thus, there is no doubt about the fact that Eng-lish pronunciation is of great importance, especially for English teachers whose pronunciation exerts far-reaching and direct influ-ences on that of students. Some of College English teachers, however, have poor pronunciation;most of them cannot distinguish/n/from/l/. Therefore, it is of huge practical value to commit to the research on the mistakes made by College English teachers in pronunciation of/n/&/l/and analyze the underlying causes in the hope of helping teachers to improve their poor pronuncia-tion.

  6. Nebraska Prostate Cancer Research Program (United States)


    MacDonald, Richard G; Mehta, Parmender P; Mott, Justin L; Naslavsky, Naava; Palanimuthu Ponnusamy, Moorthy; Ramaley, Robert F; Sorgen, Paul L; regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer, Cancer Cell 19 (2011) 575–586. [29] B.J. Feldman , D... Feldman , The development of androgen-independent prostate cancer, Nat. Rev. Cancer 1 (2001) 34–45. [30] J.D. Debes, D.J. Tindall, Mechanisms of androgen

  7. Teacher Professional Development through Collaborative Action Research: Impact on Foreign English-Language Teaching and Learning (United States)

    Banegas, Dario; Pavese, Anahi; Velazquez, Aurelia; Velez, Sandra Maria


    In 2011 we, a group of English-as-a-foreign-language teachers at a secondary school in Argentina, decided to investigate our teaching practices through collaborative action research so as to improve our students' learning opportunities and thus revitalise English-language teaching in our context. We implemented and evaluated the integration of…

  8. Personal and Impersonal Authorial References: A Contrastive Study of English and Italian Linguistics Research Articles (United States)

    Molino, Alessandra


    A cross-cultural approach is taken to analyse Linguistics research articles in English and Italian in terms of 1) the use of exclusive first-person subject pronouns in English and first-person inflected verbs in Italian, and 2) the passive voice in both languages and "si" constructions in Italian. The aim is to determine whether personal and…

  9. Researching the Teaching of Subject English: Socio-Cultural Theories and Methods (United States)

    Exley, Beryl


    I come to this article as an experienced primary and middle years teacher and midcareer university-based academic with a vested interest in researching the message systems of the disciplinary field of subject English. My sociocultural perspective challenges those who view English teaching predominantly as a cognitive act of learning to read or…

  10. Overlooked and Understudied? A Survey of Current Trends in Research on Adult English Language Learners (United States)

    Mathews-Aydinli, Julie


    This article provides a synthesis and review of 41 recent research studies focusing on the population of adult English language learners (ELLs) studying in nonacademic contexts. It notes the unique qualities and importance of understanding the English-language needs of this population, provides a critical overview of the existing literature, and…

  11. African Organization for Research and Training in Cancer: position and vision for cancer research on the African Continent


    Ogunbiyi, J. Olufemi; Stefan, D. Cristina; Timothy R. Rebbeck


    The African Organization for Research and training in Cancer (AORTIC) bases the following position statements on a critical appraisal of the state on cancer research and cancer care in Africa including information on the availability of data on cancer burden, screening and prevention for cancer in Africa, cancer care personnel, treatment modalities, and access to cancer care.

  12. Research on Teaching Model in Business English Writing

    Institute of Scientific and Technical Information of China (English)

    WEN Chuan-shu


    According to the characteristics of Business English Writing Course,this essay analyses the teaching status, then in the frame of communication theory, it puts forward a new teaching model-PIADA. It is proved that this new teaching model can explore the teacher’s subjective initiative, mobilize the enthusiasm of the students fully, make the teaching process more systemat-ic and scientific, and eventually greatly improve students' English writing ability.

  13. Research on Computer English Teaching based on WEB Network

    Institute of Scientific and Technical Information of China (English)

    Liwen WANG


    With the continuous progress of the integration of information technology and English teaching course under the network environment, the traditional teaching mode cannot meet to listening teaching resources requirement, Web listening corpus is the main way to solve the problem. The paper design the small Web corpus for university English listening teaching development based on the introduction of Web corpus, and this corpus has realized to the listening material retrieval, browsing, online listening watch and update functions.

  14. Forging a Link between Research and Pedagogy: A Holistic Framework for Evaluating Business English Materials (United States)

    Chan, Clarice S. C.


    In the last two decades, a great deal of applied linguistics research has been conducted in different areas of business English. However, despite many highly relevant research findings, the interface between research and pedagogy remains weak. One reason behind this lack of interface is that research findings from different studies are rarely…

  15. Chinese Teaching English as a Foreign Language (TEFL) Academics' Perceptions about Research in a Transitional Culture (United States)

    Bai, Li; Millwater, Jan; Hudson, Peter


    Research capacity building has become a prominent theme in higher education institutions in China and across the world. However, Chinese Teaching English as a Foreign Language academics' research output has been quite limited. In order to build their research capacity, it is necessary to understand their perceptions about research. This case study…

  16. DCB - Cancer Immunology, Hematology, and Etiology Research (United States)

    Part of NCI’s Division of Cancer Biology’s research portfolio, studies supported include the characterization of basic mechanisms relevant to anti-tumor immune responses and hematologic malignancies.

  17. A bibliometric analysis of diets and breast cancer research. (United States)

    Kotepui, Manas; Wannaiampikul, Sivaporn; Chupeerach, Chaowanee; Duangmano, Suwit


    Breast cancer is the most common cancer among women worldwide. The primary aim of this work was to provide an in-depth evaluation of research publications in the field of diets and breast cancer. The impact of economic outcome on national academic productivity was also investigated. Data were retrieved using Pubmed for English-language publications. The search included all research for which articles included words relating to "diets and breast cancer". Population and national income data were obtained from publicly available databases. Impact factors for journals were obtained from Journal Citation Reports® (Thomson Scientific). There were 2,396 publications from 60 countries in 384 journals with an impact factor. Among them, 1,652 (68.94%) publications were Original articles. The United States had the highest quantity (51% of total) and highest of mean impact factor (8.852) for publication. Sweden had the highest productivity of publication when adjusted for number of population (6 publications per million population). Publications from the Asian nation increased from 5.3% in 2006 to 14.6% in 2012. The Original article type was also associated with geography (p<0.001; OR=2.183; 95%CI=1.526-3.123), Asian countries produced more proportion of Original articles (82%) than those of rest of the world (67.6%). Diets and breast cancer-associated research output continues to increase annually worldwide including publications from Asian countries. Although the United States produced the most publications, European nations per capita were higher in publication output.

  18. Research Areas: Causes of Cancer (United States)

    Understanding the exposures and risk factors that cause cancer, as well as the genetic abnormalities associated with the disease, has helped us to reduce certain exposures and to ameliorate their harmful effects.

  19. Spanish researchers’ perceived difficulty writing research articles for English-medium journals: the impact of proficiency in English versus publication experience

    Directory of Open Access Journals (Sweden)

    Ana I. Moreno


    Full Text Available Previous quantitative studies suggest that the burden researchers who use English as an additional language perceive when writing research articles (RAs for publication in English (as L2 is 24% greater than the burden they perceive when they write RAs for publication in their L1. It remains unclear precisely which aspects of research article (RA writing in English present these writers with the greatest challenge and just why they perceive this increase in difficulty. A structured questionnaire comprising thirty-seven questions about researchers’ publication experiences in scientific journals in English and in Spanish was designed and sent out to all (n = 8,794 Spanish postdoctoral researchers at one research-only institution and four universities in Spain, yielding responses from 1,717 researchers. Our first results show that the discussion is the section that is perceived as more difficult to write for English-medium journals, across the four broad knowledge areas in a way that cannot be fully explained by their lower level of proficiency in English (as L2. This article proposes the rhetorical transfer hypothesis as a possible explanation for their additional difficulty. Our results also reveal that their increased perceived difficulty writing RA discussions in English (as L2 does not decrease noticeably until Spanish researchers report high or very high levels of proficiency in English (as L2 for academic or general purposes or have published on average at least 37 RAs as corresponding author in English-medium journals over the last ten years. Implications for English for Academic Purposes (EAP research and pedagogy are discussed.

  20. Cancer systems biology: signal processing for cancer research

    Institute of Scientific and Technical Information of China (English)

    Olli Yli-Harja; Antti Ylip(a)(a); Matti Nykter; Wei Zhang


    In this editorial we introduce the research paradigms of signal processing in the era of systems biology. Signal processing is a field of science traditionally focused on modeling electronic and communications systems, but recently it has turned to biological applications with astounding results. The essence of signal processing is to describe the natural world by mathematical models and then, based on these models, develop efficient computational tools for solving engineering problems. Here, we underline, with examples, the endless possibilities which arise when the battle-hardened tools of engineering are applied to solve the problems that have tormented cancer researchers. Based on this approach, a new field has emerged, called cancer systems biology. Despite its short history, cancer systems biology has already produced several success stories tackling previously impracticable problems. Perhaps most importantly, it has been accepted as an integral part of the major endeavors of cancer research, such as analyzing the genomic and epigenomic data produced by The Cancer Genome Atlas (TCGA) project. Finally, we show that signal processing and cancer research, two fields that are seemingly distant from each other, have merged into a field that is indeed more than the sum of its parts.

  1. Cancer systems biology: signal processing for cancer research. (United States)

    Yli-Harja, Olli; Ylipää, Antti; Nykter, Matti; Zhang, Wei


    In this editorial we introduce the research paradigms of signal processing in the era of systems biology. Signal processing is a field of science traditionally focused on modeling electronic and communications systems, but recently it has turned to biological applications with astounding results. The essence of signal processing is to describe the natural world by mathematical models and then, based on these models, develop efficient computational tools for solving engineering problems. Here, we underline, with examples, the endless possibilities which arise when the battle-hardened tools of engineering are applied to solve the problems that have tormented cancer researchers. Based on this approach, a new field has emerged, called cancer systems biology. Despite its short history, cancer systems biology has already produced several success stories tackling previously impracticable problems. Perhaps most importantly, it has been accepted as an integral part of the major endeavors of cancer research, such as analyzing the genomic and epigenomic data produced by The Cancer Genome Atlas (TCGA) project. Finally, we show that signal processing and cancer research, two fields that are seemingly distant from each other, have merged into a field that is indeed more than the sum of its parts.

  2. TCGA researchers identify 4 subtypes of stomach cancer (United States)

    Stomach cancers fall into four distinct molecular subtypes, researchers with The Cancer Genome Atlas (TCGA) Network have found. Scientists report that this discovery could change how researchers think about developing treatments for stomach cancer, also c

  3. Infectious Agents and Cancer Epidemiology Research Webinar Series (United States)

    Infectious Agents and Cancer Epidemiology Research Webinar Series highlights emerging and cutting-edge research related to infection-associated cancers, shares scientific knowledge about technologies and methods, and fosters cross-disciplinary discussions on infectious agents and cancer epidemiology.

  4. A Contrastive Analysis of English and Hungarian Theoretical Research Article Introductions (United States)

    Arvay, Anett; Tanko, Gyula


    The study of the structure of research articles has developed into a significant field of research. The original research focus on texts produced by English academics has been expanded over the years to allow for the investigation of the structure of texts written by academics publishing in various other languages. The ongoing discussion between…

  5. Applying a Proposal Guideline in Mentoring English Major Undergraduate Researchers in Taiwan (United States)

    Kuo, Ya-Hui


    Many colleges and universities in Taiwan have implemented research courses into the school curriculum in an effort to meet the demands of higher education and requirements of graduation. However, not many researchers have proposed a guideline in mentoring English major undergraduates in their research proposal writing in Taiwan. Furthermore, to…

  6. Preparing Palestinian Reflective English Language Teachers through Classroom Based Action Research (United States)

    Dajani, Majida "Mohammed Yousef "


    This study aimed to describe the implementation of individual action research projects among some forty English language teachers distributed in thirty Palestinian schools in Ramallah and Qabatya districts-Palestine. It aimed to analyze the outcomes of the teachers' action research as part of a broader participatory action research project that is…

  7. A Hands-On Experience of English Language Teachers as Researchers (United States)

    Yayli, Demet


    This study presents the results of a teacher research project. The analysis aimed to explore both the four teacher researchers' interpretations of conducting research in English language teaching and the nature of their collaboration with their supervisor in the procedure. The results showed that qualitative data analysis and interpreting the…

  8. The Development Desire of Non-English Major Teachers in Small Rural Primary Schools in Thailand: Participatory Action Research (United States)

    Doungprom, Usanee; Phusee-on, Songsak; Prachanant, Nawamin


    The purpose of this study was to explore some problems and desires of developing self-confidence in teaching English of non-English major teachers in rural small primary schools in Thailand with participatory action research. This study also aims to develop teacher's confidence in teaching English, enhance communicative competence and to assess…

  9. Global Trends and Research Aims for English Academic Oral Presentations: Changes, Challenges, and Opportunities for Learning Technology (United States)

    Barrett, Neil E.; Liu, Gi-Zen


    English has become the de facto language for communication in academia in many parts of the world, but English language learners often lack the language resources to make effective oral academic presentations. However, English for academic purposes (EAP) research is beginning to provide valuable insights into this emerging field. This literature…

  10. About the Breast and Gynecologic Cancer Research Group | Division of Cancer Prevention (United States)

    The Breast and Gynecologic Cancer Research Group conducts and fosters the development of research on the prevention and early detection of breast cancer, cervix and human papillomavirus (HPV)-related cancers, endometrial cancers, ovarian cancers, and precursor conditions related to these cancers. |

  11. Perspective: The case for research justice: inclusion of patients with limited English proficiency in clinical research. (United States)

    Glickman, Seth W; Ndubuizu, Adanma; Weinfurt, Kevin P; Hamilton, Carol D; Glickman, Lawrence T; Schulman, Kevin A; Cairns, Charles B


    Persons with limited English proficiency (LEP) constitute a growing portion of the U.S. population, yet they are underrepresented in clinical research. This inherently limits the societal benefits of the research and its generalizability to ethnic populations living in the United States. To illustrate the complexity associated with including LEP participants in clinical research, the authors critically evaluated LEP consent requirements posted on the Web sites of 134 academic health centers in March 2008. They found wide variability with regard to consent policies and striking interinstitutional differences in posted IRB policies and attitudes toward consent of LEP patients in research. The authors argue this variation highlights competing concerns between autonomy and justice. Outcomes-based justice requires inclusion of LEP patients in the research, yet the consent process is often resource-intensive and complex. The authors suggest that more uniform and specific guidance from federal agencies for enrollment of LEP patients in clinical research be established and that this guidance explicitly recalibrate the current balance between autonomy and justice. Investigators and institutional review boards should also develop streamlined best practices to reduce unnecessary effort and expense associated with recruitment of LEP individuals. LEP individuals should have fair access to clinical research in order to fully realize individual and societal benefits of their participation and to ensure the generalizability of scientific discovery.

  12. Phenomenology in pediatric cancer nursing research. (United States)

    Fochtman, Dianne


    What does it mean to have cancer as a child or adolescent? To understand this, researchers must study the illness from the child's point of view and listen to these children's descriptions of their "lived world." Phenomenology is a qualitative research methodology that can be used to discover and interpret meaning. To use phenomenology congruently, the philosophical background must be understood as well as the adaptation of the philosophical basis to research in the caring sciences. Only when clinicians truly understand the meaning of this illness to the child can they design nursing interventions to ease suffering and increase quality of life in children and adolescents with cancer.

  13. NIH Research Leads to Cervical Cancer Vaccine (United States)

    ... Current Issue Past Issues Sexually Transmitted Diseases NIH Research Leads to Cervical Cancer Vaccine Past Issues / Fall 2008 Table of Contents For ... mystery. Most important, however, is to have a vaccine which potentially can ... focusing their research on helping to produce second-generation HPV vaccines ...

  14. Antiproton radiation found effective in cancer research

    CERN Multimedia


    "An international collaboration of scientists has completed the first ever antiproton beam experiments designed to reveal the biological effectiveness of antiproton radiation in terminating cells used for cancer research...PBar Labs assembled the collaboration at CERN (European Organization for Nuclear Research in Geneva) to perform the measurements" (1 page).

  15. College English Students’ Autonomous Learning Motivation and Cultivation Model Research

    Institute of Scientific and Technical Information of China (English)

    王艳荣; 李娥


    Studying the autonomous learning motivation and excitation model can stimulate intrinsic motivation of foreign language learners,develop students self-management strategy evaluation are very necessary.The purpose of this paper is to give students the skills of listening and speaking for their autonomous learning.Then study the cultivation and motivation of college English students autonomous learning,hoping to make students to learn autonomous learning and stimulate their motivation fully.

  16. An Action Research on Improving Non-English Majors' English Writing by "Basic Sentence Pattern Translation Drills" (United States)

    He, Xiaoyu


    English writing plays an indispensible part in EFL (English as a Foreign Language) learning for Chinese students, which accounts for a high score in an English test in China. And it is also a comprehensive reflection of students' abilities in L2 application. However, most non-English majors in vocational and technical colleges have great trouble…

  17. Updates in colorectal cancer stem cell research

    Directory of Open Access Journals (Sweden)

    Chun-Jie Li


    Full Text Available Colorectal cancer (CRC is one of the world most common malignant tumors, also is the main disease, which cause tumor-associated death. Surgery and chemotherapy are the most used treatment of CRC. Recent research reported that, cancer stem cells (CSCs are considered as the origin of tumor genesis, development, metastasis and recurrence in theory. At present, it has been proved that, CSCs existed in many tumors including CRC. In this review, we summary the identification of CSCs according to the cell surface markers, and the development of drugs that target colorectal cancer stem cells.

  18. Radiation related basic cancer research

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung Hoon; Yoo, Young Do; Hong, Seok Il [and others


    We studied the mechanism of radiation-induced apoptosis, the factors involved signaling, and the establishment of radiation-resistant cell lines in this study. During the TGF beta-stimulated epithelial mesenchymal transition(EMT), actin rearrangement occurred first and fibronectin matrix assembly followed. These two events were considered independent since cytochalasin-D did not inhibit TGF stimulated matrix assembly and fibronectin supplementation did not induce EMT. During EMT, alpha 5 beta 1 integrin and alpha v integrin have increased but MMP activation was not accompanied, which suggest that induction of extracellular matrix and activation of integrins may be main contributor for the EMT. Serum depriving induced apoptosis of HUVECs was prevented by vascular endothelial growth factor(VEGF) and PMA. The apoptosis prevention by VEGF and PMA were conformed by DNA fragmentation assay. The p53 expression level was down regulated by VEGF and PMA compared with serum deprived HUVECs. However, VEGF and PMA induces c-Myc expression level on these cells. We made the 5 radiation-resistant clones from breast, lung and cervical cancer cells. More than 70%, 100% and 50% increased resistance was detected in breast cancer cells, lung cancer cells, and cervical cells, respectively. We carried out differential display-PCR to clone the radiation-resistant genes. 9 out of 10 genes were analyzed their sequence.

  19. Get Tested for Colon Cancer: Here's How

    Medline Plus

    Full Text Available ... Live Chat Latest News English English Español More Languages Donate Donate Cancer A-Z Stay Healthy Treatment & Support Our Research Programs Get Involved About Us Donate Live Chat ...

  20. Understanding Our Learners and Developing Reflective Practice: Conducting Action Research with English Language Learners (United States)

    Sowa, Patience A.


    This paper examines the ways in which action research projects can be used to socialize teachers to the teaching of English language learners (ELLs) as well as help these teachers develop reflective practice. Drawing on surveys, action research projects conduced with ELLs and reflection papers as data, the study explored the teachers' statements…

  1. Beyond Learning Styles: Brain-Based Research and English Language Learners (United States)

    Lombardi, Judy


    In this article, the author discusses ways in which teachers can implement brain-based research in teaching English language learners (ELLs). Teachers of ELLs can draw on recently developed brain-based research applied to other learners, in addition to their considerations of multicultural strategies, learning styles, and diverse needs. Equipped…

  2. A Framework for Test Validity Research on Content Assessments Taken by English Language Learners (United States)

    Young, John W.


    In this article, I specify a conceptual framework for test validity research on content assessments taken by English language learners (ELLs) in U.S. schools in grades K-12. This framework is modeled after one previously delineated by Willingham et al. (1988), which was developed to guide research on students with disabilities. In this framework…

  3. Constructing Transformative Experiences through Problem Posing in a High School English Research Project (United States)

    Revelle, Carol L.


    This dissertation chronicles my search to engage high school English students in inquiry as part of a formal research process. The perspective of critical literacy theory is used to describe the four phases of the problem posing process in shaping student research and action. Grounded in Freire's approach and consistent with Dewey and others who…

  4. Exploring Quality Programs for English Language Learners in Charter Schools: A Framework to Guide Future Research (United States)

    Garcia, Peggie; Morales, P. Zitlali


    Although there has been a great deal of debate about the effectiveness of charter schools in the research literature, there has been surprisingly little attention paid to English language learners (ELLs) in charter schools. Moreover, the charter school research has predominantly focused on whether or not charter schools are effective rather than…

  5. Ethical Considerations in Conducting Research with Non-Native Speakers of English (United States)

    Koulouriotis, Joanna


    The ethical considerations of three education researchers working with non-native English-speaking participants were examined from a critical theory stand-point in the light of the literature on research ethics in various disciplines. Qualitative inquiry and data analysis were used to identify key themes, which centered around honor and respect…

  6. Research-Based Methods of Reading Instruction for English Language Learners, Grades K-4 (United States)

    Vaughn, Sharon; Linan-Thompson, Sylvia


    At last, a truly helpful, practical guide for K-4 teachers who want to ensure that their approach to teaching young English language learners is based on research and grounded in proven classroom practices. The authors of ASCD's best-selling book "Research-Based Methods of Reading Instruction, Grades K-3" explain how you can help the English…

  7. Research in English Language Teaching and Learning in Israel (2004-2009) (United States)

    Aronin, Larissa; Spolsky, Bernard


    The goal of this article is to make research on English language teaching and learning published locally in Israel more widely available. Given that so many Israeli researchers are internationally trained and maintain wide connections, it necessarily omits much important work that appears in European and US journals. It focuses on shorter studies,…

  8. Principles of Effective English Language Learner Pedagogy. Research in Review 2012-3 (United States)

    Li, Jun


    The purpose of this literature review is to identify the most effective instructional principles for English language learners (ELLs) as documented by prominent researchers in the field and existing research reviews. This report is intended as a high-level synthesis of existing reviews of the literature rather than a comprehensive search and…

  9. Automation of Technology for Cancer Research. (United States)

    van der Ent, Wietske; Veneman, Wouter J; Groenewoud, Arwin; Chen, Lanpeng; Tulotta, Claudia; Hogendoorn, Pancras C W; Spaink, Herman P; Snaar-Jagalska, B Ewa


    Zebrafish embryos can be obtained for research purposes in large numbers at low cost and embryos develop externally in limited space, making them highly suitable for high-throughput cancer studies and drug screens. Non-invasive live imaging of various processes within the larvae is possible due to their transparency during development, and a multitude of available fluorescent transgenic reporter lines.To perform high-throughput studies, handling large amounts of embryos and larvae is required. With such high number of individuals, even minute tasks may become time-consuming and arduous. In this chapter, an overview is given of the developments in the automation of various steps of large scale zebrafish cancer research for discovering important cancer pathways and drugs for the treatment of human disease. The focus lies on various tools developed for cancer cell implantation, embryo handling and sorting, microfluidic systems for imaging and drug treatment, and image acquisition and analysis. Examples will be given of employment of these technologies within the fields of toxicology research and cancer research.

  10. A Comparative Research of English Translation about Chinese Historical Relics

    Institute of Scientific and Technical Information of China (English)



    Nowadays, China, with a long history and great culture, appeal to more and more foreign travelers come for a visit. In tourism, English is the most essential language in tourism. Tourist materials play important roles for travelers to understand and enjoy Chinese historical sites, but now many mistakes and problems appear in the tourist materials and many introductions of historical sites are not translated appropriately. The present paper presents the current condition and problems in tourism translation. Some tourist materials and translations are adopted to analyze the main differences in Chinese and western culture. This thesis put forward some translation techniques for those who face the translation of tourism materials.

  11. Institutional shared resources and translational cancer research

    Directory of Open Access Journals (Sweden)

    De Paoli Paolo


    Full Text Available Abstract The development and maintenance of adequate shared infrastructures is considered a major goal for academic centers promoting translational research programs. Among infrastructures favoring translational research, centralized facilities characterized by shared, multidisciplinary use of expensive laboratory instrumentation, or by complex computer hardware and software and/or by high professional skills are necessary to maintain or improve institutional scientific competitiveness. The success or failure of a shared resource program also depends on the choice of appropriate institutional policies and requires an effective institutional governance regarding decisions on staffing, existence and composition of advisory committees, policies and of defined mechanisms of reporting, budgeting and financial support of each resource. Shared Resources represent a widely diffused model to sustain cancer research; in fact, web sites from an impressive number of research Institutes and Universities in the U.S. contain pages dedicated to the SR that have been established in each Center, making a complete view of the situation impossible. However, a nation-wide overview of how Cancer Centers develop SR programs is available on the web site for NCI-designated Cancer Centers in the U.S., while in Europe, information is available for individual Cancer centers. This article will briefly summarize the institutional policies, the organizational needs, the characteristics, scientific aims, and future developments of SRs necessary to develop effective translational research programs in oncology. In fact, the physical build-up of SRs per se is not sufficient for the successful translation of biomedical research. Appropriate policies to improve the academic culture in collaboration, the availability of educational programs for translational investigators, the existence of administrative facilitations for translational research and an efficient organization

  12. Impact of proteomics on bladder cancer research

    DEFF Research Database (Denmark)

    Celis, Julio E; Gromova, Irina; Moreira, José Manuel Alfonso


    Detecting bladder cancer at an early stage and predicting how a tumor will behave and act in response to therapy, as well as the identification of new targets for therapeutic intervention, are among the main areas of research that will benefit from the current explosion in the number of powerful ...

  13. A Research on Chinese Thinking Influencing English Writing Process

    Institute of Scientific and Technical Information of China (English)



    L2 writing process is a bilingual event.L2 writers have both LI and L2 at their disposal when they composing in L2. The tendency of LI occurrence varies with individuals composing activities.L2 Writers are more likely to depend on LI, when they were managing their writing process, generating and organizing ideas; but more likely to depend on L2 when undertaking task--examining and text--generating activities. This paper focuses on the influence of LI on L2, and the purpose is to demonstrate that Chinese thinking decreases with the improvement of English proficiency, but the amount of Chinese thinking decreases by a different margin.

  14. PS2-37: Oral Cancer Information on the Web: Assessing the Quality and Content of English and Spanish Oral Cancer Websites (United States)

    Irwin, Jeannie Y; Thyvalikakath, Thankam; Schleyer, Titus; Wali, Teena; Kerr, Ross


    Background/Aims: In the United States, about 8,000 people a year die from oral cancer and more than 30,000 new cases are diagnosed annually. A recent study showed that 80% of American adult Internet users have searched the Web for health information and 15% of those specifically searched for dental health information. Having high quality oral cancer information available via the Web is important given the significance of this health problem. The goal of this study was to evaluate the quality and content of multiple English and Spanish oral cancer websites. Methods: We developed a search strategy using the keywords: oral cancer, mouth cancer, and tongue cancer to find oral cancer sites via Medline Plus, Google, and Yahoo. We then used the translations cancer oral, cancer de la boca, and cancer de la lengua to search Medline Plus en Español, Google Español, and Yahoo Telemundo. We added sites to the datasets based on inclusion/exclusion criteria. Two native speaking raters evaluated each site within their set for quality using the modified Information Quality Tool (IQT). We then developed a survey tool to asses the content of the sites. Two native speaking oral cancer experts evaluated each site within their set using this new tool. Results: Our search strategy produced 24 English language sites and 24 Spanish language sites for evaluation. English language websites had an average IQT score of 74.7 (out of 100) and average content score of 51.5 (out of 100). Spanish-language sites had an average IQT score of 48.8 and an average content score of 25.9. Conclusions: Despite higher scores for the English language websites, our analysis showed that there was a great variation in overall quality and content with room for improvement for both language types. English sites could make the biggest improvements by providing more information about their sponsors and who controls site content as well as updated and fixing links and author credentials. The Spanish sites should

  15. Prostate Cancer Research Training Program (United States)


    Associate, Department of Internal Medicine (319-356-4159) Cardiology /Directory/Micha elSchultz.html Dr. Schultz’s...Core, DNA Core, Flow Cytometry Core, to name but a few. For research that includes laboratory animals, professional, humane veterinary care is

  16. Commentary on "Research in Secondary English, 1912-2011: Historical Continuities and Discontinuities in the NCTE Imprint" (United States)

    Hillocks, George, Jr.


    Jory Brass and Leslie David Burns provide a useful and informative review of research appearing in the "English Journal" ("EJ") and "Research in the Teaching of English" ("RTE") over the past 100 years. It is a bit unfortunate, if understandable, to exclude books and articles in other journals, because such a restriction excludes many pieces of…

  17. Prostate Cancer Research Training Program (United States)


    Iowa. It is conveniently located on the northern edge of the campus and is served by the free Cambus transportation system. The Mayflower has...and museums (art, natural history, and sports). In addition, there are a large number of restaurants ranging from fast food to fine dining...of Iowa. It is conveniently located on the west campus near the research labs and is served by the free Cambus transportation system. The

  18. Ubiquitin proteasome system research in gastrointestinal cancer. (United States)

    Zhong, Jia-Ling; Huang, Chang-Zhi


    The ubiquitin proteasome system (UPS) is important for the degradation of proteins in eukaryotic cells. It is involved in nearly every cellular process and plays an important role in maintaining body homeostasis. An increasing body of evidence has linked alterations in the UPS to gastrointestinal malignancies, including esophageal, gastric and colorectal cancers. Here, we summarize the current literature detailing the involvement of the UPS in gastrointestinal cancer, highlighting its role in tumor occurrence and development, providing information for therapeutic targets research and anti-gastrointestinal tumor drug design.

  19. Review of Developments in Research into English as a Lingua Franca (United States)

    Jenkins, Jennifer; Cogo, Alessia; Dewey, Martin


    We begin by considering how the recent phenomenon of English as a Lingua Franca (henceforth ELF) fits in with the older notion of lingua francas in general as well as with older versions of ELF. We then explore the beginnings of ELF in its modern manifestation, including the earliest ELF research, and tackle the thorny issue of defining ELF. After…

  20. The Effect of the Research Assessment Exercise on Organisational Culture in English Universities: Collegiality versus Managerialism (United States)

    Yokoyama, Keiko


    The purpose of the study is to identify the effect of the research assessment exercise (RAE) on the balance between collegiality and managerialism in English universities. The article examines the institutional strategies for the 2001 RAE and its effect on organisational culture, identifying change in governance, management and leadership in…

  1. Developmental Reading and English Assessment in a Researcher-Practitioner Partnership. CCRC Working Paper No. 85 (United States)

    Perin, Dolores; Raufman, Julia; Kalamkarian, Hoori Santikian


    This paper reports findings from a researcher-practitioner partnership that assessed the readiness for postsecondary reading and writing demands of 211 students in developmental reading and English courses in two community colleges. An assessment battery was designed for the study, comprising two standardized tests and five projectdeveloped tasks.…

  2. Replication Research in Comparative Genre Analysis in English for Academic Purposes (United States)

    Basturkmen, Helen


    In recent years a number of comparative studies based on an established approach to genre analysis have been published in the English for Academic Purposes (EAP) literature. Studies in this emerging strand of research typically aim to identify how the rhetorical structure of a particular genre (a text type) or part of a genre may vary across…

  3. Investigating Move Structure of English Applied Linguistics Research Article Discussions Published in International and Thai Journals (United States)

    Amnuai, Wirada; Wannaruk, Anchalee


    This study investigates the rhetorical move structure of English applied linguistic research article Discussions published in Thai and international journals. Two corpora comprising of 30 Thai Discussions and 30 international Discussions were analyzed using Yang & Allison's (2003) move model. Based on the analysis, both similarities and…

  4. Thinking Allowed: Managing Innovation in English Language Education--A Research Agenda (United States)

    Waters, Alan


    In Waters (2009), the author attempted to capture the "state of the art" in theorising, practice, and research activity about the management of innovation in English language education (ELE). In this article, he reprises a number of areas in that review, to identify where the field would benefit from further enquiry about how to…

  5. English Language Teaching Management Research in Post-Compulsory Contexts: Still "Crawling Out"? (United States)

    Walker, John


    This paper explores the field of post-compulsory English Language Teaching (ELT) management research, enquiring into its identity, legitimacy and development, by identifying and discussing issues, problems, and controversies. It reviews the nature of the ELT sector as a predominantly commercial educational service with a significant role in "inner…

  6. Ideologies "of" English Language Teaching in Iranian Academic Research: Mainstream, Alternative, and Beyond (United States)

    Mirhosseini, Seyyed-Abdolhamid; Ghafar Samar, Reza


    Mainstream trends of English language teaching (ELT) are predominantly constructed within the epistemological boundaries shaped by the traditional conceptions of linguistics, learning, and teaching as well as positivist research methodology. What tends to be overshadowed by such conceptions is the underlying foundational belief structure of ELT…

  7. Research on English Language Teaching and Learning in Argentina (2007-2013) (United States)

    Porto, Melina; Montemayor-Borsinger, Ann; López-Barrios, Mario


    In this article we review research on English as a foreign language (EFL) teaching and learning published in Argentina between 2007 and 2013. This is the first review of a Latin American country in this series. Argentina has a century-long tradition of training EFL teachers but a comparatively shorter though fruitful history of foreign language…

  8. A Constructive Teaching Model in Learning Research Concept for English Language Teaching Students (United States)

    Anwar, Khoirul


    This is a study to focus on analyzing the use of constructive teaching method toward the students' motivation in learning content subject of Introduction to Research of English Language Teaching. By using a mix-method of qualitative and quantitative analysis, the data are collected by using questionnaire and classroom observation. The…

  9. The Use of Abbreviations in English-Medium Astrophysics Research Paper Titles: A Problematic Issue (United States)

    Méndez, David I.; Alcaraz, M. Ángeles


    In this study, we carry out a qualitative and quantitative analysis of abbreviations in 300 randomly collected research paper titles published in the most prestigious European and US-based Astrophysics journals written in English. Our main results show that the process of shortening words and groups of words is one of the most characteristic and…

  10. Design Based Research Methodology for Teaching with Technology in English (United States)

    Jetnikoff, Anita


    Design based research (DBR) is an appropriate method for small scale educational research projects involving collaboration between teachers, students and researchers. It is particularly useful in collaborative projects where an intervention is implemented and evaluated in a grounded context. The intervention can be technological, or a new program…

  11. The Tentative Research on Cultural Identity in China English and on How to Teach Chinese Culture in College English Class

    Institute of Scientific and Technical Information of China (English)



      With the rapid pace of globalization,English has become the global language or international language which is playing all increasingly important role in international communication. Inevitably involved in this process,China has experienced all up⁃ surge of English learning. The author drawing support from the theories in sociolinguistics and intercultural communication, And analysis the sets of teaching materials used in college English class, for example, The New Horizon College English. The unbal⁃ anced proportion of Chinese culture input to western culture input in textbooks is one of the main reasons why Chinese college stu⁃ dents are incompetent in expressing Chinese culture in English.

  12. Translating basic research in cancer patient care

    Directory of Open Access Journals (Sweden)

    Marcello Maugeri-Saccà


    Full Text Available With the advent of molecular targeted therapies and the development of high-throughput biotechnologies, it has become evident that progress in cancer research is largely due to the creation of multidisciplinary teams able to plan clinical trials supported by appropriate molecular hypotheses. These efforts have culminated in the identification and validation of biomarkers predictive of response, as well as in the generation of more accurate prognostic tools. The identification of cancer stem cells has provided further insights into mechanisms of cancer, and many studies have tried to translate this biological notion into prognostic and predictive information. In this regard, new agents targeting key stemness-related pathways have entered the clinical development, and preliminary data suggested an encouraging antitumor activity.

  13. Microarray Applications in Cancer Research (United States)

    Kim, Il-Jin; Kang, Hio Chung


    DNA microarray technology permits simultaneous analysis of thousands of DNA sequences for genomic research and diagnostics applications. Microarray technology represents the most recent and exciting advance in the application of hybridization-based technology for biological sciences analysis. This review focuses on the classification (oligonucleotide vs. cDNA) and application (mutation-genotyping vs. gene expression) of microarrays. Oligonucleotide microarrays can be used both in mutation-genotyping and gene expression analysis, while cDNA microarrays can only be used in gene expression analysis. We review microarray mutation analysis, including examining the use of three oligonucleotide microarrays developed in our laboratory to determine mutations in RET, β-catenin and K-ras genes. We also discuss the use of the Affymetrix GeneChip in mutation analysis. We review microarray gene expression analysis, including the classifying of such studies into four categories: class comparison, class prediction, class discovery and identification of biomarkers. PMID:20368836

  14. Perceptions of Patient-Provider Communication in Breast and Cervical Cancer-Related Care: A Qualitative Study of Low-Income English- and Spanish-Speaking Women


    Melissa A. Simon; Ragas, Daiva M.; Nonzee, Narissa J.; Phisuthikul, Ava M.; Luu, Thanh Ha; Dong, XinQi


    To explore patient perceptions of patient-provider communication in breast and cervical cancer-related care among low-income English- and Spanish- speaking women, we examined communication barriers and facilitators reported by patients receiving care at safety net clinics. Participants were interviewed in English or Spanish after receiving an abnormal breast or cervical cancer screening test or cancer diagnosis. Following an inductive approach, interviews were coded and analyzed by the langua...

  15. Research Timeline: Dictionary Use by English Language Learners (United States)

    Nesi, Hilary


    The history of research into dictionary use tends to be characterised by small-scale studies undertaken in a variety of different contexts, rather than larger-scale, longer-term funded projects. The research conducted by dictionary publishers is not generally made public, because of its commercial sensitivity, yet because dictionary production is…

  16. Introduction: Epidemiologic research and prevention of occupational cancer in Europe.


    Boffetta, P.; Kogevinas, M.


    Research on occupational cancer epidemiology has been an important area of occupational health in Europe since the early studies were conducted in the United Kingdom in the 1950s and 1960s. During the last decade, occupational cancer research in Europe has gained an international dimension and become increasingly interdisciplinary in nature. At present, occupational exposures might be responsible for 13 to 18% of lung cancers, 2 to 10% of bladder cancers, and 2 to 8% of laryngeal cancers in E...

  17. Improving Cancer Care Through Nursing Research. (United States)

    Mayer, Deborah K


    Nursing research and nurse researchers have been an integral and significant part of the Oncology Nursing Society's (ONS's) history, as evidenced by the development of the Nursing Research Committee within a few years of ONS's establishment. Ruth McCorkle, PhD, RN, FAAN, was the committee's first chairperson in 1979. This was followed by the creation of the Advanced Nursing Research Special Interest Group in 1989 under the leadership of Jean Brown, PhD, RN, FAAN. ONS also began to recognize nurse researchers in 1994 by creating the annual ONS Distinguished Researcher Award to recognize the contributions of a member who has conducted or promoted research that has enhanced the science and practice of oncology nursing. The list of recipients and of their work is impressive and reflects the wide range of our practice areas (see for the recipient list). In addition, the ONS Foundation began funding research in 1981 and has distributed more than $24 million in research grants, research fellowships, and other scholarships, lectures, public education projects, and career development awards (ONS Foundation, 2015). And, in 2006, the Putting Evidence Into Practice resource was unveiled, which provides evidence-based intervention reviews for the 20 most common problems experienced by patients with cancer and their caregivers (www.ons

  18. English as a medium of academic identity: attitudes to using English for research and teaching at Nantes University.


    Reynolds, Alexandra


    This socio-linguistic study investigates attitudes of French speakers of English to using English for academic purposes. The study is situated within the post-Fioraso Law period (2013), which sees France joining the process described as the ‘internationalisation’ of Higher Education in Europe. This study confirms that rather than encouraging multiple languages in academia, the term ‘internationalisation’ implies ‘Englishisation’ in Europe by contributing to studies which show how English is i...

  19. Gaps in nutritional research among older adults with cancer


    Presley, Carolyn J.; Dotan, Efrat; Soto-Perez-de-Celis, Enrique; Jatoi, Aminah; Mohile, Supriya G.; Won, Elizabeth; Alibhai, Shabbir; Kilari, Deepak; Harrison, Robert; Klepin, Heidi D.; Wildes, Tanya M.; Mustian, Karen; Demark-Wahnefried, Wendy


    Nutritional issues among older adults with cancer are an understudied area of research despite significant prognostic implications for treatment side effects, cancer-specific mortality, and overall survival. In May of 2015, the National Cancer Institute and the National Institute on Aging co-sponsored a conference focused on future directions in geriatric oncology research. Nutritional research among older adults with cancer was highlighted as a major area of concern as most nutritional cance...

  20. A Milestone in Cancer Research and Treatment in India (United States)

    Tata Memorial Center is celebrating 75 years of leadership service towards cancer control and research in India. In honor of this anniversary, TMC is hosting A Conference of New Ideas in Cancer – Challenging Dogmas on February 26-28th, 2016 as part of its platinum jubilee events. CGH Director, Dr. Ted Trimble, will give a plenary talk: "Thinking Outside the Box in Cancer Research - Perspectives from the US NCI” in the session titled: Future of Cancer Research: US and European perspectives.

  1. Research on Teaching College English Writing%大学英语写作教学研究

    Institute of Scientific and Technical Information of China (English)

    陈尹晴; 林芋辰


    大学英语写作是大学英语教学中的一个重要的组成部分,大学生英语写作教学是为了解决学生的写作困难,培养学生写作能力,总结写作教学最突出的问题是在于解决大学生写作思维的变换以及选择写作的测评模式。%Teaching College English Writing is one of the most important parts of College English Teaching. The purpose for teach⁃ing English Writing is to help the students’solving English writing difficulties, cultivating their English writing capabilities. Through the researching process, we found that converting the Chinese way of thinking to English version and choosing the right testing mode are the two most important aspects.

  2. Effective Reading Programs for Spanish-Dominant English Language Learners (ELLs) in the Elementary Grades: A Synthesis of Research (United States)

    Cheung, Alan C. K.; Slavin, Robert E.


    This review synthesizes research on English reading outcomes of all types of programs for Spanish-dominant English language learners (ELLs) in elementary schools. It is divided into two major sections. One focuses on studies of language of instruction and one on reading approaches for ELLs holding constant language of instruction. A total of 13…

  3. Effective Reading Programs for Spanish Dominant English Language Learners (ELLs) in the Elementary Grades: A Synthesis of Research. Educator's Summary (United States)

    Center for Research and Reform in Education, 2012


    This review synthesizes research on English reading outcomes of all types of programs for Spanish-dominant ELLs in elementary school. It is divided into two major sections: the effect of language of instruction on achievement (i.e., bilingual vs. English-only instruction) and effective reading approaches for ELLs other than the use of native…

  4. The cancer translational research informatics platform

    Directory of Open Access Journals (Sweden)

    Johnson Kimberly


    Full Text Available Abstract Background Despite the pressing need for the creation of applications that facilitate the aggregation of clinical and molecular data, most current applications are proprietary and lack the necessary compliance with standards that would allow for cross-institutional data exchange. In line with its mission of accelerating research discoveries and improving patient outcomes by linking networks of researchers, physicians, and patients focused on cancer research, caBIG (cancer Biomedical Informatics Grid™ has sponsored the creation of the caTRIP (Cancer Translational Research Informatics Platform tool, with the purpose of aggregating clinical and molecular data in a repository that is user-friendly, easily accessible, as well as compliant with regulatory requirements of privacy and security. Results caTRIP has been developed as an N-tier architecture, with three primary tiers: domain services, the distributed query engine, and the graphical user interface, primarily making use of the caGrid infrastructure to ensure compatibility with other tools currently developed by caBIG. The application interface was designed so that users can construct queries using either the Simple Interface via drop-down menus or the Advanced Interface for more sophisticated searching strategies to using drag-and-drop. Furthermore, the application addresses the security concerns of authentication, authorization, and delegation, as well as an automated honest broker service for deidentifying data. Conclusion Currently being deployed at Duke University and a few other centers, we expect that caTRIP will make a significant contribution to further the development of translational research through the facilitation of its data exchange and storage processes.

  5. A professional development scheme for non-native speaking teachers of English from the Arab world: an action research study


    Rabi, Sally A


    Following an action research framework, my research investigates professional development for English Language teachers in the Arab World, who are non-native\\ud speakers of English themselves.\\ud \\ud The thesis has five chapters: Literature Review, Critical Contexts, Methodology of the Study, Data Analysis and Presentation, and finally the Discussion and Findings of the\\ud research. The Literature Review covers works relevant to the area of the study in relation to existing teacher practices,...

  6. About the Prostate and Urologic Cancer Research Group | Division of Cancer Prevention (United States)

    The Prostate and Urologic Cancer Research Group conducts and supports research on prostate and bladder cancers, and new approaches to clinical prevention studies including cancer immunoprevention. The group develops, implements and monitors research efforts in chemoprevention, nutrition, genetic, and immunologic interventions, screening, early detection and other prevention strategies. |

  7. NCI Community Oncology Research Program Approved | Division of Cancer Prevention (United States)

    On June 24, 2013, the National Cancer Institute (NCI) Board of Scientific Advisors approved the creation of the NCI Community Oncology Research Program (NCORP). NCORP will bring state-of-the art cancer prevention, control, treatment and imaging clinical trials, cancer care delivery research, and disparities studies to individuals in their own communities. |

  8. Adherence to the World Cancer Research Fund/American Institute for Cancer Research recommendations and breast cancer risk. (United States)

    Harris, Holly R; Bergkvist, Leif; Wolk, Alicja


    The World Cancer Research Fund/American Association for Cancer Research (WCRF/AICR) has published eight nutrition-related recommendations for the prevention of cancer. However, few prospective studies have examined these recommendations by breast cancer hormone receptor subtype and only one case-control study has included the dietary supplements recommendation in their evaluation. We investigated whether adherence to the WCRF/AICR cancer prevention recommendations was associated with breast cancer incidence, overall and by hormone receptor subtype, in the Swedish Mammography Cohort. Among 31,514 primarily postmenopausal women diet and lifestyle factors were assessed with a self-administered food frequency questionnaire. A score was constructed based on adherence to the recommendations for body fatness, physical activity, energy density, plant foods, animal foods, alcoholic drinks and dietary supplements (score range 0-7). Cox proportional hazard models were used to calculate hazard ratios (HRs) and 95% confidence intervals (95% CIs). During 15 years of follow-up 1,388 cases of breast cancer were identified. Women who met six to seven recommendations had a 51% decreased risk of breast cancer compared to women meeting only zero to two recommendations (95% CI = 0.35-0.70). The association between each additional recommendation met and breast cancer risk was strongest for the ER-positive/PR-positive subtype (HR = 0.86; 95% CI = 0.79-0.94), while for the ER-negative/PR-negative subtype the individual recommendations regarding plant and animal foods were most strongly associated with reduced risk. Our findings support that adherence to the WCRF/AICR recommendations reduces breast cancer risk in a population of primarily postmenopausal women. Promoting these recommendations to the public could help reduce breast cancer incidence.

  9. Use of CT colonography in the English Bowel Cancer Screening Programme (United States)

    Plumb, Andrew A; Halligan, Steve; Nickerson, Claire; Bassett, Paul; Goddard, Andrew F; Taylor, Stuart A; Patnick, Julietta; Burling, David


    Objective To examine use of CT colonography (CTC) in the English Bowel Cancer Screening Programme (BCSP) and investigate detection rates. Design Retrospective analysis of routinely coded BCSP data. Guaiac faecal occult blood test (gFOBt)-positive screenees undergoing CTC from June 2006 to July 2012 as their first-line colonic investigation were included. Abnormalities found at CTC, subsequent polyp, adenoma and cancer detection and positive predictive value (PPV) were calculated. Detection rates were compared with those observed in gFOBt-positive screenees investigated by colonoscopy. Multilevel logistic regression was used to examine factors associated with variable detection. Results 2731 screenees underwent CTC. Colorectal cancer (CRC) or polyps were suspected in 1027 individuals (37.6%; 95% CI 33.8% to 41.4%); 911 of these underwent confirmatory testing. 124 screenees had CRC (4.5%) and 533 had polyps (19.5%), 468 adenomatous (17.1%). Overall detection was 24.1% (95% CI 21.5% to 26.6%) for CRC or polyps and 21.7% (95% CI 19.2% to 24.1%) for CRC or adenoma. Advanced neoplasia was detected in 504 screenees (18.5%; 95% CI 16.1% to 20.8%). PPV for CRC or polyp was 72.1% (95% CI 66.6% to 77.6%). By comparison, 9.0% of 72 817 screenees undergoing colonoscopy had cancer and 50.6% had polyps; advanced neoplasia was detected in 32.7%. CTC detection rates and PPV were higher at centres with experienced radiologists (>1000 examinations) and at high-volume centres (>175 cases/radiologist/annum). Centres using three-dimensional interpretation detected more neoplasia. Conclusions In the BCSP, detection rates after positive gFOBt are lower for CTC than colonoscopy, although populations undergoing the two tests are different. Centres with more experienced radiologists have higher detection and accuracy. Rigorous quality assurance of BCSP radiology is needed. PMID:23955527

  10. Cancer survivorship research: a review of the literature and summary of current NCI-designated cancer center projects. (United States)

    Harrop, J Phil; Dean, Julie A; Paskett, Electra D


    The number of cancer survivors and the amount of cancer survivorship research have grown substantially during the past three decades. This article provides a review of interventional and observational cancer survivorship research efforts as well as a summary of current cancer survivorship research projects being conducted by National Cancer Institute-designated cancer centers in an effort to identify areas that need further attention.

  11. Educating Low-SES and LEP Survivors About Breast Cancer Research: Pilot Test of the Health Research Engagement Intervention (United States)

    Nickell, Alyssa; Burke, Nancy J.; Cohen, Elly; Caprio, Maria


    The Health Research Engagement Intervention (HREI) aims to reduce information and access disparities for breast cancer research opportunities among low-socioeconomic status (SES) and limited English proficient (LEP) breast cancer survivors by providing neutral, non-trial-specific information about health research via a trusted patient navigator. Qualitative methods in the context of a community-based participatory research design were used to iteratively design the HREI in collaboration with community-based care navigators from a trusted community organization, Shanti Project, and to locate appropriate research studies in collaboration with a web-based trial-matching service, (BCT). Navigators were first trained in clinical trials and health research and then to deliver the HREI, providing feedback that was incorporated into both the HREI design and BCT's interface. Our intervention pilot with low SES and LEP survivors (n=12) demonstrated interest in learning about “health research.” All 12 participants opted to obtain more information when offered the opportunity. Post-intervention questionnaires showed that three of 11 (27 %) participants independently pursued additional information about research opportunities either online or by phone in the week following the intervention. Post-intervention navigator questionnaires indicated that navigators could confidently and efficiently deliver the intervention. LEP patients who pursued information independently faced language barriers. The HREI is a promising and potentially scalable intervention to increase access to neutral information about breast cancer research opportunities for low-SES and LEP individuals. However, in order for it to be effective, systems barriers to participation such as language accessibility at sources of health research information must be addressed. PMID:24744119

  12. Educating low-SES and LEP survivors about breast cancer research: pilot test of the Health Research Engagement Intervention. (United States)

    Nickell, Alyssa; Burke, Nancy J; Cohen, Elly; Caprio, Maria; Joseph, Galen


    The Health Research Engagement Intervention (HREI) aims to reduce information and access disparities for breast cancer research opportunities among low-socioeconomic status (SES) and limited English proficient (LEP) breast cancer survivors by providing neutral, non-trial-specific information about health research via a trusted patient navigator. Qualitative methods in the context of a community-based participatory research design were used to iteratively design the HREI in collaboration with community-based care navigators from a trusted community organization, Shanti Project, and to locate appropriate research studies in collaboration with a web-based trial-matching service, (BCT). Navigators were first trained in clinical trials and health research and then to deliver the HREI, providing feedback that was incorporated into both the HREI design and BCT's interface. Our intervention pilot with low SES and LEP survivors (n = 12) demonstrated interest in learning about "health research." All 12 participants opted to obtain more information when offered the opportunity. Post-intervention questionnaires showed that three of 11 (27 %) participants independently pursued additional information about research opportunities either online or by phone in the week following the intervention. Post-intervention navigator questionnaires indicated that navigators could confidently and efficiently deliver the intervention. LEP patients who pursued information independently faced language barriers. The HREI is a promising and potentially scalable intervention to increase access to neutral information about breast cancer research opportunities for low-SES and LEP individuals. However, in order for it to be effective, systems barriers to participation such as language accessibility at sources of health research information must be addressed.

  13. Progress through Collaboration - Office of Cancer Clinical Proteomics Research (United States)

    The National Cancer Institute (NCI), through the Office of Cancer Clinical Proteomics Research (OCCPR), has signed two Memorandums of Understanding (MOUs) in the areas of sharing proteomics reagents and protocols and also in regulatory science.

  14. The research of computer multimedia assistant in college English listening (United States)

    Zhang, Qian


    With the technology development of network information, there exists more and more seriously questions to our education. Computer multimedia application breaks the traditional foreign language teaching and brings new challenges and opportunities for the education. Through the multiple media application, the teaching process is full of animation, image, voice, and characters. This can improve the learning initiative and objective with great development of learning efficiency. During the traditional foreign language teaching, people use characters learning. However, through this method, the theory performance is good but the practical application is low. During the long time computer multimedia application in the foreign language teaching, many teachers still have prejudice. Therefore, the method is not obtaining the effect. After all the above, the research has significant meaning for improving the teaching quality of foreign language.


    Directory of Open Access Journals (Sweden)

    Maria Carolina Coelho Chimenti


    Full Text Available The present article is based on a field research that aimed to provide educational subsidies for the use of digital technologies in teaching and learning process of English language, in two classes of the fifth grade from the elementary school, at the public school located in Campinas, São Paulo, Brazil. Based on the perspective of childhood pedagogy, which conceives the child as the protagonist and also (reproductive of knowledge, activities were carried with YouTube videos, online games, music, and many other learning objects. Likewise, observations, interviews and questionnaires were made with teachers and students involved in the research. Based on the action research, we analyzed aspects related to the contribution of some digital resources in teaching and learning of English at elementary school and we obtained many elements that allowed us to know the importance of learning a foreign language in the childhood nowadays, mainly English, and how new technologies can make learning more contextualized, meaningful, motivating children for language learning in a context in which they can be (criative.

  16. English Language Learners with Reading Disabilities: A Review of the Literature and the Foundation for a Research Agenda. Research Report. ETS RR-09-20 (United States)

    Shore, Jane R.; Sabatini, John


    The issue of identifying reading difficulties and disabilities in English language learners (ELLs) is a complex one. It is an area that draws on the diverse disciplines of first- and second-language acquisition, literacy, English language learning, and reading, including differences and disabilities research. This literature review aims to…

  17. Aquatic invasive species: Lessons from cancer research (United States)

    Sepulveda, Adam; Ray, Andrew; Al-Chokhachy, Robert K.; Muhlfeld, Clint C.; Gresswell, Robert E.; Gross, Jackson A.; Kershner, Jeffrey L.


    Aquatic invasive species are disrupting ecosystems with increasing frequency. Successful control of these invasions has been rare: Biologists and managers have few tools for fighting aquatic invaders. In contrast, the medical community has long worked to develop tools for preventing and fighting cancer. Its successes are marked by a coordinated research approach with multiple steps: prevention, early detection, diagnosis, treatment options and rehabilitation. The authors discuss how these steps can be applied to aquatic invasive species, such as the American bullfrog (Lithobates catesbeianus), in the Northern Rocky Mountain region of the United States, to expedite tool development and implementation along with achievement of biodiversity conservation goals.

  18. Data Collected in 1959 by English Research Vessels at Serial and Surface Hydrographic Stations (NODC Accession 6900852) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The present volume contains data collected in 1959 by English research vessels at serial and surface hydrographic stations. The data list are preceded by a number of...

  19. Research on existing problems and solving strategies——of English listening teaching in junior high school-taking a Nanchang high school as the example

    Institute of Scientific and Technical Information of China (English)



    In this article,we have made a deep research on existing problems and solving strategies of English listening teaching in junior high school,the goal of which is to improve the English listening teaching in the future.

  20. The iPad as a Research Tool for the Understanding of English Plurals by English, Chinese, and Other L1 Speaking 3- and 4-Year-Olds. (United States)

    Xu Rattanasone, Nan; Davies, Benjamin; Schembri, Tamara; Andronos, Fabia; Demuth, Katherine


    Learning about what young children with limited spoken language know about the grammar of their language is extremely challenging. Researchers have traditionally used looking behavior as a measure of language processing and to infer what overt choices children might make. However, these methods are expensive to setup, require specialized training, are time intensive for data analysis and can have considerable dropout rates. For these reasons, we have developed a forced choice task delivered on an iPad based on our eye-tracking studies with English monolinguals (Davies et al., 2016, under review). Using the iPad we investigated 3- and 4-year-olds' understanding of the English plural in preschool centers. The primary aim of the study was to provide evidence for the usefulness of the iPad as a language research tool. We evaluated the usefulness of the iPad with second language (L2) learning children who have limited L2 language skills. Studies with school aged Chinese-speaking children show below native performance on English inflectional morphology despite 5-6 years of immersion (Jia, 2003; Jia and Fuse, 2007; Paradis et al., 2016). However, it is unclear whether this is specific only to children who speak Chinese as their first language (L1) or if younger preschoolers will also show similar challenges. We tested three groups of preschoolers with different L1s (English, Chinese, and other languages). L1 Chinese children's performance was below both English monolinguals and children speaking Other L1 languages, providing evidence that English inflections are specifically challenging for Chinese-speaking children. The results provide further evidence to support previous eye-tracking findings with monolinguals and studies with older bilinguals. The study provides evidence for the usefulness of iPads as research tool for studying language acquisition. Implications for future application of the iPad as a teaching and intervention tool, and limitations for the method, are

  1. Gaps in nutritional research among older adults with cancer. (United States)

    Presley, Carolyn J; Dotan, Efrat; Soto-Perez-de-Celis, Enrique; Jatoi, Aminah; Mohile, Supriya G; Won, Elizabeth; Alibhai, Shabbir; Kilari, Deepak; Harrison, Robert; Klepin, Heidi D; Wildes, Tanya M; Mustian, Karen; Demark-Wahnefried, Wendy


    Nutritional issues among older adults with cancer are an understudied area of research despite significant prognostic implications for treatment side effects, cancer-specific mortality, and overall survival. In May of 2015, the National Cancer Institute and the National Institute on Aging co-sponsored a conference focused on future directions in geriatric oncology research. Nutritional research among older adults with cancer was highlighted as a major area of concern as most nutritional cancer research has been conducted among younger adults, with limited evidence to guide the care of nutritional issues among older adults with cancer. Cancer diagnoses among older adults are increasing, and the care of the older adult with cancer is complicated due to multimorbidity, heterogeneous functional status, polypharmacy, deficits in cognitive and mental health, and several other non-cancer factors. Due to this complexity, nutritional needs are dynamic, multifaceted, and dependent on the clinical scenario. This manuscript outlines the proceedings of this conference including knowledge gaps and recommendations for future nutritional research among older adults with cancer. Three common clinical scenarios encountered by oncologists include (1) weight loss during anti-cancer therapy, (2) malnutrition during advanced disease, and (3) obesity during survivorship. In this manuscript, we provide a brief overview of relevant cancer literature within these three areas, knowledge gaps that exist, and recommendations for future research.

  2. Current Research and Management of Ovarian Cancer in China

    Institute of Scientific and Technical Information of China (English)

    GUMeijiao; SHIWei


    Ovarian cancer is ne of the most lethal malignant tumors in China,represents the third most common cancer after cervical cancer and endometrial cancer,and the first leading cause of death from hynaecological cancers.Due to the lack of effective screening strategies and the absence of symptoms in early-stage of disease,over 70% of patients present at an advanced stage.Despite the advances in surgical techniques and conventional chemotheraphy,the prognosis of ovarian cancer has not been improved significantly,and indeed the long-term survival for patients with advanced disease does not exceed 20%.The aetiology of ovarian cancer temains poorly understood.In China,the major focus of research is to clarify the mechanism underlying ovarian cancer,develop more effective life-saving diagnostic and therapeutic measures,and undertake more population-based studies.This article summarizes current research,diagnosis and management of ovarian cancer in China.


    Directory of Open Access Journals (Sweden)

    I Nyoman Suka Sanjaya


    Full Text Available The study examines whether English and Indonesian research articles written by their respective native speaker scholars are significantly different from each other in terms of the number of hedges used. Hedges are rhetorical features (e.g. may, perhaps, suggest used to withhold complete commitment to the truth-value of propositions. The ultimate goal of the study is to examine whether Indonesian scholars need special instruction in hedging propositions. The assumption underlying the present study is that when they write in English, Indonesian scholars will deploy rhetorical features inherent in the Indonesian academic writing. Statistical analysis on 52 Applied Linguistics research articles (26 from each language reveals that English research articles contain significantly more hedges than their Indonesian counterparts (Mann-Whitney U = 68.00, n1 = n2 = 26, p < 0.05, r = - 0.69, suggesting that Indonesian scholars are indeed in need of instruction that specifically focuses on hedging propositions in English.


    Institute of Scientific and Technical Information of China (English)

    Zhang Caihong


    During the course of English teaching in middle schools, grammar teaching is always a focus argued about by English researchers and English teachers- -Is it necessary to teach grammar? Which approach or method td grammar teaching may help the students improve the effects of learning a foreign language and enhance their ability to use the foreign language? In view of this circumstance, the author does an experiment on teaching grammar in the framework of CLT to prove whether CLT is really more effective for students to master grammar knowledge than traditional method and whether CLT can improve the students' ability to express themselves freely, properly and fluently.

  5. A Genre Analysis of English and Iranian Research Articles Abstracts in Applied Linguistics and Mathematics

    Directory of Open Access Journals (Sweden)

    Biook Behnam


    Full Text Available In recent years, genre studies have attracted the attention of many researchers. The aim of the present study was to observe the differences in generic structure of abstract written by English native and non-native (Iranian students in two disciplines of mathematics and applied linguistics. To this end, twenty native English students’ abstract texts from each discipline and the same number of non-native (Iranian ones were selected. In this study, Hyland’s (2000 five‐move model was used to identify the rhetorical structure of the four sets of texts. After analyzing each text, the main moves were extracted and the frequencies of each one were calculated and compared. The cross-disciplinary and cross‐linguistic analyses reveal that linguistics abstracts follow a conventional scheme, but mathematics abstracts in these two languages do not exhibit the usual norms in terms of moves. Besides, greater difference in move structure is seen across languages in mathematics. The findings of the study have some pedagogical implications for academic writing courses for graduate students, especially students from non-English backgrounds in order to facilitate their successful acculturation into these disciplinary communities. Keywords: Genre Analysis, mathematics, applied linguistics

  6. Job Opening for Medical Officer in DCP’s Breast and Gynecologic Cancer Research Group | Division of Cancer Prevention (United States)

    The Breast and Gynecologic Cancer Research Group (BGCRG), Division of Cancer Prevention (DCP), National Cancer Institute (NCI), has an opening for an experienced Medical Officer. BGCRG focuses on fostering the development and conduct of research on the prevention and early detection of breast cancer, cervix and human papillomavirus (HPV)-related cancers, endometrial cancers, ovarian cancers, and precursor conditions related to these cancers. Learn more about BGCRG. |

  7. Towards meeting the research needs of Australian cancer consumers

    Directory of Open Access Journals (Sweden)

    Saunders Carla


    Full Text Available Abstract Background There is a growing amount of literature to support the view that active involvement in research by consumers, especially informed and networked consumers, benefits the quality and direction of research itself, the research process and, most importantly, people affected by cancer. Our exploratory project focuses on identifying their priorities and developing a process to assess the research needs of Australian cancer consumers which may be useful beyond the cancer scenario. Methods This project was consumer initiated, developed and implemented, with the assistance of a leading Australian cancer consumer advocacy group, Cancer Voices NSW (CVN. Such direct involvement is unusual and ensures that the priorities identified, and the process itself, are not influenced by other interests, regardless how well-intentioned they may be. The processes established, and data collection via a workshop, followed by a questionnaire to confirm and prioritise findings, and comparison with a similar UK exercise, are detailed in this paper. Results Needs across five topic areas reflecting cancer control domains (prevention and risk; screening and diagnosis; treatment; survivorship; and end of life were identified. Cancer consumers high priority research needs were found to be: earlier diagnosis of metastatic cancers; the extent of use of best practice palliative care guidelines; identifying barriers to cancer risk behaviour change; and environmental, nutrition and lifestyle risk factors for people with cancer. A process for identifying consumers’ research priorities was developed and applied; this may be useful for further investigation in this under-studied area. Conclusion The findings provide a model for developing a consumer derived research agenda in Australia which can be used to inform the strategic direction of cancer research. Consumers have been seeking a workable method to achieve this and have worked in collaboration with a major

  8. Differential network analysis in human cancer research. (United States)

    Gill, Ryan; Datta, Somnath; Datta, Susmita


    A complex disease like cancer is hardly caused by one gene or one protein singly. It is usually caused by the perturbation of the network formed by several genes or proteins. In the last decade several research teams have attempted to construct interaction maps of genes and proteins either experimentally or reverse engineer interaction maps using computational techniques. These networks were usually created under a certain condition such as an environmental condition, a particular disease, or a specific tissue type. Lately, however, there has been greater emphasis on finding the differential structure of the existing network topology under a novel condition or disease status to elucidate the perturbation in a biological system. In this review/tutorial article we briefly mention some of the research done in this area; we mainly illustrate the computational/statistical methods developed by our team in recent years for differential network analysis using publicly available gene expression data collected from a well known cancer study. This data includes a group of patients with acute lymphoblastic leukemia and a group with acute myeloid leukemia. In particular, we describe the statistical tests to detect the change in the network topology based on connectivity scores which measure the association or interaction between pairs of genes. The tests under various scores are applied to this data set to perform a differential network analysis on gene expression for human leukemia. We believe that, in the future, differential network analysis will be a standard way to view the changes in gene expression and protein expression data globally and these types of tests could be useful in analyzing the complex differential signatures.

  9. Empirical research on implementation of full English teaching mode in the professional courses of the engineering doctoral students


    Zhang Yunxia; Li Li


    Under the historical background of increasingly close international exchanges, the international education trend becomes increasingly apparent. The doctoral students’ education is the highest part of the higher education. The improvement of the doctoral students’ ability to use English for academic research is increasingly important. Taking full English course of the doctoral students in the School of Control Science and Engineering of Tongji University as example, this paper explores the res...

  10. Lung Cancer:Symptoms, Diagnosis, Treatments & Research | NIH MedlinePlus the Magazine (United States)

    ... of this page please turn Javascript on. Feature: Lung Cancer Lung Cancer: Symptoms, Diagnosis, Treatments & Research Past Issues / Winter 2013 ... lung cancer are given intravenously or by mouth. Lung Cancer Research The large-scale National Lung Screening Trial, ...

  11. A Proposal for Critical-Pragmatic Pedagogical Approaches to English for Research Publication Purposes

    Directory of Open Access Journals (Sweden)

    James Corcoran


    Full Text Available Despite the increasing demands on many multilingual scholars outside the centre(s of scientific knowledge production to publish their research in international scholarly journals, the support for such academic writing for publication is uneven at best. Existing English for research publication purposes (ERPP instruction typically aims to aid multilingual scholars in achieving genre-based expectations and/or navigating the submission and review process, but it often does not address the politics of English-language knowledge production. In this paper, informed by an empirical case study and a theory building perspective, we address the need for a sustained program of courses/workshops for multilingual scholars in the (semi- periphery and propose a means of operationalizing a critical-pragmatic approach to such course/workshop content. Our empirically-driven model is informed by the results of a recent case study investigation into an intensive ERPP intervention designed to address multilingual Spanish-speaking L1 scholars’ challenges with writing research articles for publication in indexed (Web of Science international scientific journals. Our model lays the groundwork for a more critical approach to ERPP pedagogy, one that attempts to attend more fully to the needs of multilingual scholars within an asymmetrical market of global knowledge production.

  12. The John Milner Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention (United States)

    The Nutritional Science Research Group in the Division of Cancer Prevention at the National Cancer Institute, National Institutes of Health and the Department of Nutrition at the Clinical Center, National Institutes of Health, and the U.S. Department of Agriculture’s Beltsville Human Nutrition Research Center are offering a one-week educational opportunity in Nutrition and Cancer Prevention Research for individuals with a sustained commitment to nutrition and health promotion. |

  13. Biography: Dr Iain Frame, director of research, prostate cancer UK. (United States)

    Frame, Iain; Maprayil, Sophia


    Sophia Maprayil, Commissioning Editor for Expert Review of Anticancer Therapy, talks to Dr Iain Frame, Director of Research for Prostate Cancer UK. Iain is Prostate Cancer UK's first Director of Research, responsible for overseeing the development and implementation of the charity's ambitious new research strategy. He joined Prostate Cancer UK in 2012 from Diabetes UK where he held the post of Research Director for 5 years. Since joining Prostate Cancer UK in 2012 Iain has overseen a dramatic increase in the charity's research spend, from 2 million a year, to 7.5 million a year. Previously Iain worked in research management at the Wellcome Trust and before that as a parasitologist and researcher exploring various aspects of molecular biology of a number of different parasites.

  14. The potential consequences for cancer care and cancer research of Brexit (United States)

    Selby, Peter; Lawler, Mark; Baird, Richard; Banks, Ian; Johnston, Patrick; Nurse, Paul


    Following the UK “Brexit” vote in June 2016, there are many uncertainties and risks for cancer research and cancer care in the UK. These are summarised and the importance of sustained engagement and influence from the cancer community on UK governments is emphasised. PMID:28275394

  15. Bringing global cancer leaders together at the 4th Annual Symposium on Global Cancer Research (United States)

    The Annual Symposium on Global Cancer Research held in April 2016 was developed with a special focus on innovative and low-cost technologies in global cancer control, and brought inspiring keynote speakers such as John Seffrin, Former CEO of the American Cancer Society, and Tom Bollyky, Senior Fellow for Global Health at the Council on Foreign Relations.

  16. The potential consequences for cancer care and cancer research of Brexit. (United States)

    Selby, Peter; Lawler, Mark; Baird, Richard; Banks, Ian; Johnston, Patrick; Nurse, Paul


    Following the UK "Brexit" vote in June 2016, there are many uncertainties and risks for cancer research and cancer care in the UK. These are summarised and the importance of sustained engagement and influence from the cancer community on UK governments is emphasised.

  17. Cancer complementary and alternative medicine research at the US National Cancer Institute. (United States)

    Jia, Libin


    The United States National Cancer Institute (NCI) supports complementary and alternative medicine (CAM) research which includes different methods and practices (such as nutrition therapies) and other medical systems (such as Chinese medicine). In recent years, NCI has spent around $120 million each year on various CAM-related research projects on cancer prevention, treatment, symptom/side effect management and epidemiology. The categories of CAM research involved include nutritional therapeutics, pharmacological and biological treatments, mind-body interventions, manipulative and body based methods, alternative medical systems, exercise therapies, spiritual therapies and energy therapies on a range of types of cancer. The NCI Office of Cancer Complementary and Alternative Medicine (OCCAM) supports various intramural and extramural cancer CAM research projects. Examples of these cancer CAM projects are presented and discussed. In addition, OCCAM also supports international research projects.

  18. Prostate Cancer Stem Cells: Research Advances. (United States)

    Jaworska, Dagmara; Król, Wojciech; Szliszka, Ewelina


    Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression of cancer into invasive and metastatic disease. Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease.

  19. Prostate Cancer Stem Cells: Research Advances

    Directory of Open Access Journals (Sweden)

    Dagmara Jaworska


    Full Text Available Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression of cancer into invasive and metastatic disease. Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease.

  20. The iPad as a Research Tool for the Understanding of English Plurals by English, Chinese and Other L1 Speaking 3- and 4-year-olds.

    Directory of Open Access Journals (Sweden)

    Nan Xu Rattanasone


    Full Text Available Learning about what young children with limited spoken language know about the grammar of their language is extremely challenging. Researchers have traditionally used looking behavior as a measure of language processing and to infer what overt choices children might make. However, these methods are expensive to setup, require specialized training, are time intensive for data analysis and can have considerable dropout rates. For these reasons, we have developed a forced choice task delivered on an iPad based on our eye-tracking studies with English monolinguals (Davies et al., accepted; Davies et al., under review. Using the iPad we investigated 3- and 4-year-olds’ understanding of the English plural in preschool centers. The primary aim of the study was to provide evidence for the usefulness of the iPad as a language research tool. We evaluated the usefulness of the iPad with second language (L2 learning children who have limited L2 language skills. Studies with school aged Chinese-speaking children show below native performance on English inflectional morphology despite 5-6 years of immersion (Jia, 2003; Jia & Fuse, 2007; Paradis et al., 2016. However, it is unclear whether this is specific only to children who speak Chinese as their first language (L1 or if younger preschoolers will also show similar challenges. We tested three groups of preschoolers with different L1s (English, Chinese, and Other languages. L1 Chinese children’s performance was below both English monolinguals and children speaking Other L1 languages, providing evidence that English inflections are specifically challenging for Chinese-speaking children. The results provide further evidence to support previous eye-tracking findings with monolinguals and studies with older bilinguals. The study provides evidence for the usefulness of iPads as research tool for studying language acquisition. Implications for future application of the iPad as a teaching and intervention tool

  1. Research on cancer diagnosis in Malaysia: current status. (United States)

    Looi, L M; Zubaidah, Z; Cheah, P L; Cheong, S K; Gudum, H R; Iekhsan, O; Ikram, S I; Jamal, R; Mak, J W; Othman, N H; Puteri, J N; Rosline, H; Sabariah, A R; Seow, H F; Sharifah, N A


    Cancer is a major morbidity and mortality concern in Malaysia. Based on National Cancer Registry data, the Malaysian population is estimated to bear a cancer burden of about 40,000 new cases per year, and a cumulative lifetime risk of about 1:4. Cancer research in Malaysia has to consider needs relevant to our population, and resources constraints. Hence, funding bodies prioritise cancers of high prevalence, unique to our community and posing specific clinical problems. Cancer diagnosis is crucial to cancer management. While cancer diagnosis research largely aims at improvements in diagnostic information towards more appropriate therapy, it also impacts upon policy development and other areas of cancer management. The scope of cancer diagnosis upon which this paper is based, and their possible impact on other R&D areas, has been broadly categorized into: (1) identification of aetiological agents and their linkages to the development of precancer and cancer (impact on policy development, cancer prevention and treatment), (2) cancer biology and pathogenesis (impact on cancer prevention, treatment strategies and product development), (3) improvements in accuracy, sensitivity and specificity in cancer detection, monitoring and classification (impact on technology development) and (4) prognostic and predictive parameters (impact on treatment strategies). This paper is based on data collected by the Working Group on Cancer Diagnosis Research for the First National Conference on Cancer Research Coordination in April 2004. Data was collated from the databases of Institutions/Universities where the authors are employed, the Ministry of Science, Technology and Innovation (MOSTI) and targeted survey feedback from key cancer researchers. Under the 7th Malaysia Plan, 76 cancer projects were funded through the Intensified Research in Priority Areas (IRPA) scheme of MOSTI, amounting to almost RM15 million of grant money. 47(61.8%) of these projects were substantially in cancer

  2. Cancer Research Repository for Individuals With Cancer Diagnosis, High Risk Individuals, and Individuals With No History of Cancer (Control) (United States)


    Pancreatic Cancer; Thyroid Cancer; Lung Cancer; Esophageal Cancer; Thymus Cancer; Colon Cancer; Rectal Cancer; GIST; Anal Cancer; Bile Duct Cancer; Duodenal Cancer; Gallbladder Cancer; Gastric Cancer; Liver Cancer; Small Intestine Cancer; Peritoneal Surface Malignancies; Familial Adenomatous Polyposis; Lynch Syndrome; Bladder Cancer; Kidney Cancer; Penile Cancer; Prostate Cancer; Testicular Cancer; Ureter Cancer; Urethral Cancer; Hypopharyngeal Cancer; Laryngeal Cancer; Lip Cancer; Oral Cavity Cancer; Nasopharyngeal Cancer; Oropharyngeal Cancer; Paranasal Sinus Cancer; Nasal Cavity Cancer; Salivary Gland Cancer; Skin Cancer; CNS Tumor; CNS Cancer; Mesothelioma; Breastcancer; Leukemia; Melanoma; Sarcoma; Unknown Primary Tumor; Multiple Myeloma; Ovarian Cancer; Endometrial Cancer; Vaginal Cancer

  3. Towards discovery-driven translational research in breast cancer

    DEFF Research Database (Denmark)


    Discovery-driven translational research in breast cancer is moving steadily from the study of cell lines to the analysis of clinically relevant samples that, together with the ever increasing number of novel and powerful technologies available within genomics, proteomics and functional genomics......, promise to have a major impact on the way breast cancer will be diagnosed, treated and monitored in the future. Here we present a brief report on long-term ongoing strategies at the Danish Centre for Translational Breast Cancer Research to search for markers for early detection and targets for therapeutic...... biology approach to fight breast cancer....

  4. Action research to promote medical students' motivation in an English for Specific Purposes class. (United States)

    Dehnad, Afsaneh; Nasser, Hayedeh


    Action research is an attempt to seek immediate solutions to the problems experienced in educational settings. In this type of research, teachers are the researchers who intend to make instant reforms to develop, and improve their teaching styles and reflect on pedagogical practices. The purpose of this study was to conduct an action research to tackle the problem of students' low motivation in English classes at the medical school of Iran University of Medical Sciences in fall 2010. Participants of this study were 98 third-semester ESP students of medicine. To reform the situation and promote students' motivation to participate in classes more actively and eagerly, the researchers changed the syllabus by applying Kemmis and McTaggart's (1988) cyclical model of action research, and adopting task-based teaching. Data was collected by means of interviews with both teachers and students to determine the changes to be made in the syllabus, classroom observations to monitor students' behavioral changes, and a questionnaire to assess students' attitudes towards the changes. This research study had a number of valuable outcomes the most important of which was a change in classroom behavior of the students.

  5. Thesis and Research Writing in English by Indonesian Higher Degree Students Studying Overseas

    Directory of Open Access Journals (Sweden)

    Lloyd Holliday


    Full Text Available Indonesian Research Degree Student studying overseas in Australian Universities, ie. those undertaking a PhD, EdD, or Master Degree by Coursework and Minor Thesis, have exactly the same problems in thesis writing as local Australian students. They may have minor problems of language in writing in English as a result of transfer from Bahasa Indonesia. But the major problems of all first time research degree students is learning how to become researchers and how to present their research in a discourse format as a thesis or dissertation that has become the assepted norm internationally. This paper firstly examines some of the common surface written language problems of Indonesian Higher Degree Students. This data id drawn from an analysis of actual drafts of these written over the last ten years by a range of Indonesian students. Secondly, the paper discusses the nature of developing as a researcher and the associated problems of how this influences the presentation of research. And thirdly, the paper reflects on ways in which the process of learning of think and write as a researcher can be facilitated.

  6. [The applications and advantages of Drosophila melanogaster in cancer research]. (United States)

    Huo, Guitao; Lu, Jianjun; Qu, Zhe; Lin, Zhi; Zhang, Di; Yang, Yanwei; Li, Bo


    The common fruit fly, Drosophila melanogaster, has been used to study human disease as a model organism for many years. Many basic biological, physiological, and neurological properties are conserved between mammals and fly. Moreover, Drosophila melanogaster has its unique advantage as a model organism. Recent studies showed that the high level of signaling pathway conservation in tumorigenesis between fly and human and its feasible genetic operation make fly an effective model for oncology research. Numerous research findings showed Drosophila melanogaster was an ideal model for studying the molecular mechanisms of tumorigenesis, invasion and metastasis. This review mainly focuses on the advantages of Drosophila melanogaster in cancer research, established models used for the research of specific cancers and prospective research direction of oncology. It is hoped that this paper can provide insight for cancer research and development of anti-cancer drugs.

  7. Mandates, needs, equitable resources, and current research in English language teacher education: The case of Turkey

    Directory of Open Access Journals (Sweden)

    Saban Cepik


    Full Text Available Improving the quality of English language teacher education (ELTE programs has become a major point of consideration; however, such programmatic evaluations are markedly rare. This study utilizes both numeric and interpretive qualitative data in a blended research design. The study addresses, vis-à-vis current research in related fields: What is the current situation of the Turkish ELTE programs in terms of curriculum strength and faculty resources? How do the program directors and teacher candidates envision the situation of their programs in terms of curriculum strength and faculty resources? Data included 45 ELTE curricula, interviews with 24 program directors and pre-service teachers, documents, and test scores. Findings revealed several significant associations between school type (public/private and rank (low/high and the number of faculty with expertise in critical areas in the field. Qualitative critical evaluations suggest both perceptual matches and mismatches between program directors and teacher candidates regarding programmatic strengths and weaknesses.

  8. Next generation distributed computing for cancer research. (United States)

    Agarwal, Pankaj; Owzar, Kouros


    Advances in next generation sequencing (NGS) and mass spectrometry (MS) technologies have provided many new opportunities and angles for extending the scope of translational cancer research while creating tremendous challenges in data management and analysis. The resulting informatics challenge is invariably not amenable to the use of traditional computing models. Recent advances in scalable computing and associated infrastructure, particularly distributed computing for Big Data, can provide solutions for addressing these challenges. In this review, the next generation of distributed computing technologies that can address these informatics problems is described from the perspective of three key components of a computational platform, namely computing, data storage and management, and networking. A broad overview of scalable computing is provided to set the context for a detailed description of Hadoop, a technology that is being rapidly adopted for large-scale distributed computing. A proof-of-concept Hadoop cluster, set up for performance benchmarking of NGS read alignment, is described as an example of how to work with Hadoop. Finally, Hadoop is compared with a number of other current technologies for distributed computing.

  9. Major clinical research advances in gynecologic cancer in 2015 (United States)


    In 2015, fourteen topics were selected as major research advances in gynecologic oncology. For ovarian cancer, high-level evidence for annual screening with multimodal strategy which could reduce ovarian cancer deaths was reported. The best preventive strategies with current status of evidence level were also summarized. Final report of chemotherapy or upfront surgery (CHORUS) trial of neoadjuvant chemotherapy in advanced stage ovarian cancer and individualized therapy based on gene characteristics followed. There was no sign of abating in great interest in immunotherapy as well as targeted therapies in various gynecologic cancers. The fifth Ovarian Cancer Consensus Conference which was held in November 7–9 in Tokyo was briefly introduced. For cervical cancer, update of human papillomavirus vaccines regarding two-dose regimen, 9-valent vaccine, and therapeutic vaccine was reviewed. For corpus cancer, the safety concern of power morcellation in presumed fibroids was explored again with regard to age and prevalence of corpus malignancy. Hormone therapy and endometrial cancer risk, trabectedin as an option for leiomyosarcoma, endometrial cancer and Lynch syndrome, and the radiation therapy guidelines were also discussed. In addition, adjuvant therapy in vulvar cancer and the updated of targeted therapy in gynecologic cancer were addressed. For breast cancer, palbociclib in hormone-receptor-positive advanced disease, oncotype DX Recurrence Score in low-risk patients, regional nodal irradiation to internal mammary, supraclavicular, and axillary lymph nodes, and cavity shave margins were summarized as the last topics covered in this review. PMID:27775259

  10. The Research on the Silence Phenomena of Students in College English Classroom Teaching

    Institute of Scientific and Technical Information of China (English)



    This paper analyzes the reasons that resulted in silence phenomena in college English classroom teaching,and gives some feasible suggestions to break the classroom silence in English classroom teaching.

  11. [Research progression of translational medicine in gastric cancer]. (United States)

    Li, Maoran; Zhao, Gang; Zhu, Chunchao


    Gastric cancer is one of the most common malignant tumors which is a great threat to human health. In recent years, the reform of surgical mordalities and the optimization of radiation and chemotherapy is still far from reducing morbidity and mortality of gastric cancer. As a new research pattern, translational medicine has emerged in various clinical subjects, which leads to remarkable effects. In this paper, the definition and development of translational medicine, molecular markers and drug treatment of gastric cancer will be discussed and the feasibility of translational medicine in the treatment of gastric cancer will be explained. In our opinion, the intervention of translational medicine could change the current situation that scientific researches is severely disconnected with clinical practice and increase the detection rate of gastric cancer and the effective rate of adjuvant therapy after surgery to improve the prognosis of patients with gastric cancer.

  12. The Changing Landscape of Lung Cancer Research and Treatment (United States)

    Along with the Lung Cancer Social Media (#LCSM) community, the National Cancer Institute will be co-hosting a lively and interactive Google Hangout on Air about the changing landscape of lung cancer research and treatment. During the chat, viewers will have the opportunity to pose questions to a panel of lung cancer experts including NCI's Dr. Shakun Malik, the head of thoracic oncology therapeutics, Roy S. Herbst, MD, PhD, Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven and David Tom Cooke MD FACS, Head, Section of General Thoracic Surgery University of California, Davis. You can also learn more and follow along on the #LCSM Chat page. The chat will be moderated by lung cancer advocate and #LCSM co-founder, Janet Freeman-Daily. To ask questions of our experts, simply use the #LCSM hashtag during the chat.

  13. General Research on Intercultural Facework Competence of Non-English Major Postgraduates

    Institute of Scientific and Technical Information of China (English)



    This paper examines different intercultural facework competence in various intercultural conflicts between English major and non-English major postgraduates based on S.Ting-Toomey’s face-negotiation theory. Data were collected by questionnaire called DCT and analyzed with Mean Comparison and ANOVA. The results show that (1) the facework competence of non-English major postgraduate students is lower than English major students in genera; (2) gender difference has been found to be a significant factor.

  14. Biomedical text mining and its applications in cancer research. (United States)

    Zhu, Fei; Patumcharoenpol, Preecha; Zhang, Cheng; Yang, Yang; Chan, Jonathan; Meechai, Asawin; Vongsangnak, Wanwipa; Shen, Bairong


    Cancer is a malignant disease that has caused millions of human deaths. Its study has a long history of well over 100years. There have been an enormous number of publications on cancer research. This integrated but unstructured biomedical text is of great value for cancer diagnostics, treatment, and prevention. The immense body and rapid growth of biomedical text on cancer has led to the appearance of a large number of text mining techniques aimed at extracting novel knowledge from scientific text. Biomedical text mining on cancer research is computationally automatic and high-throughput in nature. However, it is error-prone due to the complexity of natural language processing. In this review, we introduce the basic concepts underlying text mining and examine some frequently used algorithms, tools, and data sets, as well as assessing how much these algorithms have been utilized. We then discuss the current state-of-the-art text mining applications in cancer research and we also provide some resources for cancer text mining. With the development of systems biology, researchers tend to understand complex biomedical systems from a systems biology viewpoint. Thus, the full utilization of text mining to facilitate cancer systems biology research is fast becoming a major concern. To address this issue, we describe the general workflow of text mining in cancer systems biology and each phase of the workflow. We hope that this review can (i) provide a useful overview of the current work of this field; (ii) help researchers to choose text mining tools and datasets; and (iii) highlight how to apply text mining to assist cancer systems biology research.

  15. Research applications for an Object and Action Naming Battery to assess naming skills in adult Spanish-English bilingual speakers. (United States)

    Edmonds, Lisa A; Donovan, Neila J


    Virtually no valid materials are available to evaluate confrontation naming in Spanish-English bilingual adults in the U.S. In a recent study, a large group of young Spanish-English bilingual adults were evaluated on An Object and Action Naming Battery (Edmonds & Donovan in Journal of Speech, Language, and Hearing Research 55:359-381, 2012). Rasch analyses of the responses resulted in evidence for the content and construct validity of the retained items. However, the scope of that study did not allow for extensive examination of individual item characteristics, group analyses of participants, or the provision of testing and scoring materials or raw data, thereby limiting the ability of researchers to administer the test to Spanish-English bilinguals and to score the items with confidence. In this study, we present the in-depth information described above on the basis of further analyses, including (1) online searchable spreadsheets with extensive empirical (e.g., accuracy and name agreeability) and psycholinguistic item statistics; (2) answer sheets and instructions for scoring and interpreting the responses to the Rasch items; (3) tables of alternative correct responses for English and Spanish; (4) ability strata determined for all naming conditions (English and Spanish nouns and verbs); and (5) comparisons of accuracy across proficiency groups (i.e., Spanish dominant, English dominant, and balanced). These data indicate that the Rasch items from An Object and Action Naming Battery are valid and sensitive for the evaluation of naming in young Spanish-English bilingual adults. Additional information based on participant responses for all of the items on the battery can provide researchers with valuable information to aid in stimulus development and response interpretation for experimental studies in this population.

  16. Let’s Collaborate: Using Developments in Global English Research to Advance Socioculturally-oriented SLA Identity Work



    In light of the growing importance of identity work in second language acquisition (e.g., Block, 2006a, b) in Second Language Acquisition (SLA) as well as calls for SLA and World Englishes (WE) scholars (e.g., Y. Kachru, 2005) to work together, I examine how identity has been conceptualized in research on the global use of English. While such research finds its roots in the WE paradigm (e.g, B. Kachru, 2005), it has undergone contestation in recent years. Such contestation has emerged as a re...

  17. Introducing Business English

    NARCIS (Netherlands)

    Nickerson, C.; Planken, B.C.


    Introducing Business English provides a comprehensive overview of this topic, situating the concepts of Business English and English for Specific Business Purposes within the wider field of English for Special Purposes. This book draws on contemporary teaching and research contexts to demonstrate th

  18. The Future of Prostate Cancer Research and Treatment (United States)

    On January 12, 2017 prostate cancer experts William Dahut, M.D. of the National Cancer Institute and Dr. Heather Cheng, M.D. of the University of Washington had a vibrant discussion about current and future research areas and treatment options for prostate cancer. The panel was moderated by Ana Fadich, MPH, CHES Vice President at Men’s Health of the Men's Health Network.

  19. Meharry-Johns Hopkins Center for Prostate Cancer Research (United States)


    Prostate cancer, Dietary risk factors , Lycopene, Genetic predisposition, African-Americans, Cancer research training, Quality of life, Community...that of CA men (73.9 per 100,000 AA / 25.6 per 100,000 C). Genetic and dietary factors have been identified in explaining a portion of the excess...cancer may occur earlier and be more aggressive among African-American men.  Other possible risk factors include obesity , lifestyle and environmental

  20. Supportive and Palliative Care Research | Division of Cancer Prevention (United States)

    Supportive and palliative care research includes studies to prevent or treat the acute and chronic symptoms and morbidities related to cancer and its treatment, and to examine the effects of cancer and its treatment on quality of life and psychosocial issues and treatment strategies at the end of life. Active Projects can range from caregiver issues to geriatrics, physical functioning to cognitive dysfunction. | Examining symptoms and morbidities related to cancer, its treatment, quality of life and end of life.

  1. Is Clinical Research in Oesophageal Cancer in South Africa in Crisis? A Systematic Review. (United States)

    Loots, E; Sartorius, B; Madiba, T E; Mulder, C J J; Clarke, D L


    Oesophageal cancer (OC) is responsible for the second highest number of cancer-related deaths in South Africa (SA). Squamous cell carcinoma is the most prevalent type with an incidence of 46.7/100,000 and 19.2/100,000 for males and females. This is a systematic review of the clinical diagnosis and management of OC within the South African context. This protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) (registration number CRD42016034053) with adherence to PRISMA guidelines. An online search was performed using MEDLINE, EBSCOHost and PubMed. Eligibility criteria for articles included published, original peer-reviewed research addressing clinical management of oesophageal cancer in South Africa. Review articles, case reports, scientific letters and studies published in languages other than English or Afrikaans were excluded. The research terms were 'etiology', 'human', 'esophageal cancer', 'esophageal carcinoma', 'oesophageal cancer', and 'oesophageal carcinoma', 'squamous cell carcinoma', 'Africa' and 'South Africa'. A total of 336 articles were identified. Of these, 146 were immediately excluded and a further 159 were excluded after review. A total of 31 appropriate articles, i.e. 9.2% of searched articles, were included. Thirteen articles addressed chemotherapy and/or radiotherapy, 9 oesophageal luminal therapy, 7 oesophageal surgery and 2 screening. OC research of in SA over the last two decades has mainly been in the form of reviews and opinion papers. Clinical research, auditing and prospectively analysing OC management and outcomes in SA hospitals are sorely needed and should be promoted by both healthcare workers and policy makers alike.

  2. Action Research on Effects of a Pidgin English (Open to Suggestion). (United States)

    Aina, Joseph O.


    Investigates the effects of Pidgin English used for communication outside the classroom on Nigerian students' reading and writing. Concludes that knowledge of Pidgin English favorably affected Standard English reading comprehension but did not help writing. Notes that Pidgin-speaking students have solid linguistic competencies on which to build.…

  3. Research on Three-Part Argumentative Writings for English Majors in China (United States)

    Mingli, Luo


    Writing is a kind of creative thinking activity. The teaching of three-part argumentative writing is crucial in college English instruction. Many English majors that fail to write well lack sufficient input of English argumentative reading materials, use Chinese thinking and structure to express their ideas, and lack frequent and sufficient…

  4. A Research on the Gain and Cost of Bilingual Teaching of Non-English-Oriented Courses

    Institute of Scientific and Technical Information of China (English)



    In accordance with the requirement of the Ministry of Education, many Universities and colleges have begun or are beginning to adopt bilingual teaching of non-English-oriented courses with course books in English. The pu~ is to improve students' learning and acquiring of the English language during the process of studying the subject courses, and make them

  5. Research on Translation Strategy of English Subtitle Television Drama for College Students based on Cultural Differences

    Directory of Open Access Journals (Sweden)

    Zhou Gang


    Full Text Available Abstract. Translation strategy is closely-tied with the translation of ESTD (English Subtitle Television Drama. The research of translation strategy is to serve translations of ESTD in earlier days. The 21 S century is the information times. The development of science and technology is quick. Quantities of ESTD grow explosively. Translations of English Subtitle Television Dramas play a significant role in the progress of Chinese science and technology. Although the quality of traditional manual translations is very good, the speed of translation is too slow. Traditional manual translations can not meet the need of translations of ESTD day by day. It is a new topic to face the new stern challenge and follow the development's steps of the times for technical translators. The paper will discuss the transformation of translation idea, and suggest carrying on translation strategy, web page translation and software translation. Finally, the author states her views on the implementation of computer assistant translation, the managements of translation projects and information-shared platform.

  6. International Partnerships for Clinical Cancer Research (United States)

    CGH co-sponsors the 2015 International Symposium on Cancer Clinical Trials and related meetings held in partnership with the Japanese National Cancer Center (JNCC) and Embassies of France, Korea, United Kingdom (UK), and United States (US) in Tokyo on May 14 - 15, 2015.

  7. Graphic Evolution Witness the Development of Lung Cancer Translational Research

    Directory of Open Access Journals (Sweden)

    Chao ZHANG


    Full Text Available Lung cancer treatment has altered from conventional chemotherapy to targeted treatment, which now has been turned to the immunotherapy. Translational research has played an irreplaceable role during this progression which graphic evolution has witnessed. The evolution has gone through forest plot, KM-curve, waterfall plot, spider plot and timeline-area, showing us the refining concept and gradual process of lung cancer treatment undergoing from community towards individual. Even though the latest immunotherapy is getting increasingly hot, the result isn’t quite expected. Meanwhile, the limitations of conventional treatment still exist which require further research. This article will primarily illustrate the development of translational research of lung cancer via the aspect of curve evolution and analysis some abortive clinical trials in lung cancer surgery for inspiring the next graphic style and lung cancer treatment.

  8. [Recommendations for cancer prevention of World Cancer Research Fund (WCRF): situational analysis for Chile]. (United States)

    Crovetto, Mirta; Uauy, Ricardo


    The main diet-related cancers include colorectal, lung, breast in (postmenopausal) women, stomach, esophagus, prostate and pancreas. After tobacco, obesity is the leading cause of cancer; it accounts for one third of all cancers. Cancer is associated with high total body fat, abdominal fat and weight gain in adult life. These are all potentially modifiable risk factors. Consumption of a "healthy diet" and living an "active life" can significantly reduce the risk of cancer. The aim of this study was to analyze the recommendations published by the World Cancer Research Fund (WCRF) and American Institute for Cancer Research (AICR) for the prevention of cancer in 2007. We compared the recommendations of Food, Nutrition and Physical Activity and the Prevention of Cancer: a global perspective", with the national situation in Chile, analyzing the national report on the prevalence of risk factors. Our main finding was that the pattern of consumption and lifestyles differ markedly from the WCRF recommendations: we observed an over consumption of sugary drinks and high intake of processed foods high in sodium and total fat and low consumption of legumes, vegetables, fruits high in antioxidants and fiber that protect from cancer. Chile has an increased cancer prevalence which is associated with poor quality diets, rising mean body mass index and a sedentary behavior. We recommend the strengthening programs to promote healthy diets and active living, in order to reduce cancer risk.

  9. Healthy Eating for Life English as a second language curriculum: applying the RE-AIM framework to evaluate a nutrition education intervention targeting cancer risk reduction. (United States)

    Martinez, J L; Duncan, L R; Rivers, S E; Bertoli, M C; Latimer-Cheung, A E; Salovey, P


    Medically underserved US immigrants are at an increased risk for death from preventable or curable cancers due to economic, cultural, and/or linguistic barriers to medical care. The purpose of this study was to describe the evaluation of the pilot study of the Healthy Eating for Life (HE4L) English as a second language curriculum. The Reach, Effectiveness Adoption, Implementation, Maintenance (RE-AIM) model was used to design a mixed-methods approach to the evaluation of the HE4L curriculum. Successful implementation was dependent upon enthusiastic teacher and manager support of the curriculum, teachers' ability to flexibly apply the curriculum to meet student needs, and researcher provision of curriculum workbooks. HE4L can be implemented successfully in various adult education settings to teach healthy eating behaviors and English language principles. Scale-up of HE4L may depend on the development of an online version of the curriculum to avoid the costs associated with printing and distributing curriculum materials.

  10. NCI Community Oncology Research Program (NCORP) | Division of Cancer Prevention (United States)

    The NCI Community Oncology Research Program (NCORP) is a national network of cancer care investigators, providers, academia, and other organizations that care for diverse populations in health systems. View the list of publications from NCORP. | Clinical Trials network of cancer care professionals who care for diverse populations across the U.S.

  11. Biospecimen Core Resource - Office of Cancer Clinical Proteomics Research (United States)

    The purpose of this notice is to notify the community that the National Cancer Institute's (NCI’s) Office of Cancer Clinical Proteomics Research (OCCPR) is seeking sources to establish a Biospecimen Core Resource (BCR), capable of receiving, qualifying, processing, and distributing annotated biospecimens.

  12. Does cancer research focus on areas of importance to patients? (United States)

    Moorcraft, Sing Yu; Sangha, Amrit; Peckitt, Clare; Sanchez, Rodrigo; Lee, Martin; Pattison, Natalie; Wiseman, Theresa


    The majority of research ideas are proposed by clinicians or scientists and little is currently known about which areas of research patients feel are important. We performed a 4 week pilot patient survey at the Royal Marsden (a specialist cancer centre) to investigate patients' views on priorities for cancer research. A total of 780 patients completed the survey and the top research priorities were identified as: detection and prevention of cancer, scientific understanding, curative treatment and personalised treatment. The top research priorities were remarkably consistent across age, gender and a variety of tumour types. We believe that patients' views should be considered alongside those of clinicians and researchers when devising research proposals and strategies.

  13. Multilingual Researchers Internationalizing Monolingual English-Only Education through Post-Monolingual Research Methodologies

    Directory of Open Access Journals (Sweden)

    Michael Singh


    Full Text Available The argument advanced in this Special Issue of Education Sciences favors democratizing knowledge production and dissemination across the humanities and social sciences through the mainstreaming of multilingual researchers capabilities for theorizing using their full linguistic repertoire. An important contribution of the papers in this Special Issue is the promise that post-monolingual research methodology holds for collaborative projects among multilingual and monolingual researchers that tap into intercultural divergences across languages. Together these papers give warrant to multilingual researchers, including Higher Degree Researchers develop their capabilities for theorizing using their full linguistic repertoire, an educational innovation that could be of immense benefit to scholars working predominantly monolingual universities. Through their thought provoking papers presented in this Special Issue, these researchers invites those working in the education sciences to seriously consider the potential benefits of multiplying the intellectual resources used for theorizing that is possible through activating, mobilizing and deploying researchers’ multilingual resources in knowledge production and dissemination.

  14. Multilingual Researchers Internationalizing Monolingual English-Only Education through Post-Monolingual Research Methodologies


    Michael Singh


    The argument advanced in this Special Issue of Education Sciences favors democratizing knowledge production and dissemination across the humanities and social sciences through the mainstreaming of multilingual researchers capabilities for theorizing using their full linguistic repertoire. An important contribution of the papers in this Special Issue is the promise that post-monolingual research methodology holds for collaborative projects among multilingual and monolingual researchers that ta...

  15. Building capacity for sustainable research programmes for cancer in Africa. (United States)

    Adewole, Isaac; Martin, Damali N; Williams, Makeda J; Adebamowo, Clement; Bhatia, Kishor; Berling, Christine; Casper, Corey; Elshamy, Karima; Elzawawy, Ahmed; Lawlor, Rita T; Legood, Rosa; Mbulaiteye, Sam M; Odedina, Folakemi T; Olopade, Olufunmilayo I; Olopade, Christopher O; Parkin, Donald M; Rebbeck, Timothy R; Ross, Hana; Santini, Luiz A; Torode, Julie; Trimble, Edward L; Wild, Christopher P; Young, Annie M; Kerr, David J


    Cancer research in Africa will have a pivotal role in cancer control planning in this continent. However, environments (such as those in academic or clinical settings) with limited research infrastructure (laboratories, biorespositories, databases) coupled with inadequate funding and other resources have hampered African scientists from carrying out rigorous research. In September 2012, over 100 scientists with expertise in cancer research in Africa met in London to discuss the challenges in performing high-quality research, and to formulate the next steps for building sustainable, comprehensive and multi-disciplinary programmes relevant to Africa. This was the first meeting among five major organizations: the African Organisation for Research and Training in Africa (AORTIC), the Africa Oxford Cancer Foundation (AfrOx), and the National Cancer Institutes (NCI) of Brazil, France and the USA. This article summarizes the discussions and recommendations of this meeting, including the next steps required to create sustainable and impactful research programmes that will enable evidenced-based cancer control approaches and planning at the local, regional and national levels.

  16. Stem cell concepts renew cancer research. (United States)

    Dick, John E


    Although uncontrolled proliferation is a distinguishing property of a tumor as a whole, the individual cells that make up the tumor exhibit considerable variation in many properties, including morphology, proliferation kinetics, and the ability to initiate tumor growth in transplant assays. Understanding the molecular and cellular basis of this heterogeneity has important implications in the design of therapeutic strategies. The mechanistic basis of tumor heterogeneity has been uncertain; however, there is now strong evidence that cancer is a cellular hierarchy with cancer stem cells at the apex. This review provides a historical overview of the influence of hematology on the development of stem cell concepts and their linkage to cancer.

  17. 大学英语词汇教学行动研究%An Action Research of College English Vocabulary Teaching to Non-English Majors

    Institute of Scientific and Technical Information of China (English)



    作者通过两轮词汇教学行动研究,利用问卷调查、测试、访谈等手段进行实证研究,探讨了有效提高非英语专业大学生词汇水平的教学方法。通过研究得出以下结论:系统、有计划地训练与提高非英语专业大学生英语词汇学习策略运用能力及词汇学习自我效能感能够显著提高他们的词汇水平。%The author of this paper explores how to implement effective English vocabulary teaching through two rounds of action re-search in which empirical evidence was collected via questionnair surveys, tests and interviews. The finding indicates that English vo-cabulary proficiency can be improved through systematically strengthening the capacity in adopting vocabulary learning strategies and vocabulary learning self-efficacy among non-English majors.

  18. Methodological quality of English-language genetic guidelines on hereditary breast-cancer screening and management: an evaluation using the AGREE instrument

    Directory of Open Access Journals (Sweden)

    Simone Benedetto


    Full Text Available Abstract Background We examined the methodological quality of guidelines on syndromes conferring genetic susceptibility to breast cancer. Methods PubMed, EMBASE, and Google were searched for guidelines published up to October 2010. All guidelines in English were included. The Appraisal of Guidelines, Research and Evaluation (AGREE instrument was used to assess the quality of the guidelines, and their reported evidence base was evaluated. Results Thirteen guidelines were deemed eligible: seven had been developed by independent associations, and the other six had national/state endorsements. Four guidelines performed satisfactorily, achieving a score of greater than 50% in all six AGREE domains. Mean ± SD standardized scores for the six AGREE domains were: 90 ± 9% for 'scope and purpose', 51 ± 18% for 'stakeholder involvement', 55 ± 27% for 'rigour of development', 80 ± 11% for 'clarity and presentation', 37 ± 32% for 'applicability', and 47 ± 38% for 'editorial independence'. Ten of the thirteen guidelines were found to be based on research evidence. Conclusions Given the ethical implications and the high costs of genetic testing for hereditary breast cancer, guidelines on this topic should provide clear and evidence-based recommendations. Our analysis shows that there is scope for improving many aspects of the methodological quality of current guidelines. The AGREE instrument is a useful tool, and could be used profitably by guidelines developers to improve the quality of recommendations.

  19. Research Progress of Exosomes in Lung Cancer Diagnosis and Treatment

    Directory of Open Access Journals (Sweden)

    Hongbo ZOU


    Full Text Available As the leading cause of morbidity and cancer related-death worldwide, lung cancer has a serious threat to human health. Exosomes are nanoscale lipid membrane vesicles derived from multivesicles, which containing active biomolecules including proteins, lipids, nucleic acids and etc. Exosomes play important roles in lung cancer initiation and progression by promoting the formation of tumor microenvironment, enhancing tumor invasive and metastasis capability, leading to immunosuppression and resistance to chemoradiotherapy, and also have the application value in early diagnosis and treatment. This review summarizes the research progress of exosomes in tumor initiation and progression, and its roles in diagnosis and treatment of lung cancer.

  20. An Empirical Research on Developmental Assessment in Polytechnic Eng-lish Teaching

    Institute of Scientific and Technical Information of China (English)



    Developmental assessment, process-oriented and student-centered, aims at students’performance in learning process, and their development. The author of the paper conducted an empirical research of developmental assessment to her own students. By comparing the students’learning attitude, interest, motivation, strategies, performance and achievements in the experimental class with those in the controlled one, she found that developmental assessment had developed the students’comprehensive lan⁃guage competence, increased their grades in written examinations, especially in the final examination, and recorded their progress over time to have them a sense of accomplishment and become more self-confident, active, responsible and independent. There⁃fore, developmental assessment is an effective and reasonable assessment in the current polytechnic English teaching.

  1. Encountering Spaces of Resistance When Implementing Research-Based Strategies for English Language Learners (ELLs

    Directory of Open Access Journals (Sweden)

    Xaé Alicia Reyes


    Full Text Available This article discusses research findings from follow-up studies on the effects of purposeful programming designed to prepare educators who participated in either of two professional development federal grants funded by the U.S. Department of Education (REALL 2007 and LEAD 2012 to address the needs of English Language Learners (ELLs. The qualitative data gleaned through focus group interviews and responses to questionnaires collected in these studies describe both educators’ sense of self-efficacy (Bandura, 1994 and their students’ transformations as they experience success. The longitudinal data collected over a 6-year period include narratives of resistance encountered by the grant participants in spaces such as schools, districts, and the broader community, and how these challenges were approached.

  2. Breast Cancer Translational Research Center of Excellence (United States)


    the standard of care for treating breast diseases and breast cancer. This approach integrates prevention , screening, diagnosis, treatment and...follow a healthy lifestyle ?” (submitted for publication clearance April 2015). Ellsworth RE, Mamula KA, Costantino NS, Deyarmin B, Kostyniak PJ, Chi...disorders. The project will continue utilizing a multidisciplinary approach as the standard of care for treating breast diseases and breast cancer. This

  3. Big Data-Led Cancer Research, Application, and Insights. (United States)

    Brown, James A L; Ni Chonghaile, Triona; Matchett, Kyle B; Lynam-Lennon, Niamh; Kiely, Patrick A


    Insights distilled from integrating multiple big-data or "omic" datasets have revealed functional hierarchies of molecular networks driving tumorigenesis and modifiers of treatment response. Identifying these novel key regulatory and dysregulated elements is now informing personalized medicine. Crucially, although there are many advantages to this approach, there are several key considerations to address. Here, we examine how this big data-led approach is impacting many diverse areas of cancer research, through review of the key presentations given at the Irish Association for Cancer Research Meeting and importantly how the results may be applied to positively affect patient outcomes. Cancer Res; 76(21); 6167-70. ©2016 AACR.

  4. The Death of the Non-Native Speaker? English as a Lingua Franca in Business Communication: A Research Agenda (United States)

    Nickerson, Catherine


    The impact of globalisation in the last 20 years has led to an overwhelming increase in the use of English as the medium through which many business people get their work done. As a result, the linguistic landscape within which we now operate as researchers and teachers has changed both rapidly and beyond all recognition. In the discussion below,…

  5. Effective Reading Programs for Spanish Dominant English Language Learners (ELLs) in the Elementary Grades: A Synthesis of Research (United States)

    Cheung, Alan C. K.; Slavin, Robert E.


    This review synthesizes research on English reading outcomes of all types of programs for Spanish-dominant ELLs in elementary schools. It is divided into two major sections. One focuses on studies of language of instruction, and one on reading approaches for ELLs other than bilingual education. A total of 14 qualifying studies met the inclusion…

  6. Simultaneous and Comparable Numerical Indicators of International, National and Local Collaboration Practices in English-Medium Astrophysics Research Papers (United States)

    Méndez, David I.; Alcaraz, M. Ángeles


    Introduction: We report an investigation on collaboration practices in research papers published in the most prestigious English-medium astrophysics journals. Method: We propose an evaluation method based on three numerical indicators to study and compare, in absolute terms, three different types of collaboration (international, national and…

  7. Review of Doctoral Research in English Language Education in the Philippines, Singapore and Malaysia (2007-2010) (United States)

    Rubdy, Rani; Tupas, T. Ruanni F.; Villareal, Corazon D.; David, Maya Khemlani; Dumanig, Francisco Perlas


    This review highlights recent doctoral research in English language education and related areas completed between 2007 and 2010 in three countries in Southeast Asia: Singapore, Malaysia and the Philippines. Out of sixty dissertations initially chosen from major universities in these countries, five from the Philippines, four from Malaysia and…

  8. Unlocking the Research on English Learners: What We Know--and Don't Yet Know--about Effective Instruction (United States)

    Goldenberg, Claude


    Challenges are bound to arise as the vast majority of states strive to help English learners meet the Common Core State Standards. In calling for students to read complex texts, these new standards place an even greater emphasis on content knowledge and literacy skills than prior state standards. This review of available research will help…

  9. English Language Education among Young Learners in East Asia: A Review of Current Research (2004-2014) (United States)

    Butler, Yuko Goto


    The teaching of foreign languages to young learners is growing in popularity around the world. Research in this field, particularly of English as a second/foreign language education in East Asia, is a relatively new area of empirical inquiry, and it has the potential to make significant contributions to child second-language acquisition…

  10. Considering the Needs of English Language Learner Populations: An Examination of the Population Validity of Reading Intervention Research (United States)

    Moore, Brooke A.; Klingner, Janette K.


    This article synthesizes reading intervention research studies intended for use with struggling or at-risk students to determine which studies adequately address population validity, particularly in regard to the diverse reading needs of English language learners. An extensive search of the professional literature between 2001 and 2010 yielded a…

  11. General English Ability, Specific Purpose English Ability, and Computer Skills. (United States)

    Prapphal, Kanchana


    Aims to answer the following research questions: (1) Are general English ability and specific purpose English ability related to computer skills? and (2) Is general English ability transferable to specific purpose English ability? Subjects were third year science students enrolled in an English for academic purposes course. (Author/VWL)

  12. Gastric cancer research in Mexico: a public health priority. (United States)

    Sampieri, Clara Luz; Mora, Mauricio


    This study aimed review studies conducted on Mexican patients diagnosed with gastric cancer and/or diseases associated with its development, in which at least one Mexican institute has participated, and to assess their contributions to the primary and secondary prevention of this disease. A search of the Medline database was conducted using the following keywords: gastric/stomach cancer, Mexico. Studies of the Mexican population were selected in which at least one Mexican Institute had participated and where the findings could support public policy proposals directed towards the primary or secondary prevention of gastric cancer. Of the 148 studies found in the Medline database, 100 were discarded and 48 were reviewed. According to the analysis presented, these studies were classified as: epidemiology of gastric cancer (5/48); risk factors and protectors relating to gastric cancer (9/48); relationship between Helicobacter pylori and pathologies associated with gastric cancer and the development of the disease (16/48); relationship between the Epstein-Barr virus and pathologies associated with gastric cancer and the development of the disease (3/48); molecular markers for the development of diseases associated with gastric cancer and gastric cancer (15/48). Mexico requires a program for the prevention and control of gastric cancer based on national health indicators. This should be produced by a multidisciplinary committee of experts who can propose actions that are relevant in the current national context. The few studies of gastric cancer conducted on the Mexican population in national institutes highlight the poor connection that currently exists between the scientific community and the health sector in terms of resolving this health issue. Public policies for health research should support projects with findings that can be translated into benefits for the population. This review serves to identify national research groups studying gastric cancer in the Mexican

  13. Gastric cancer research in Mexico: A public health priority (United States)

    Sampieri, Clara Luz; Mora, Mauricio


    This study aimed review studies conducted on Mexican patients diagnosed with gastric cancer and/or diseases associated with its development, in which at least one Mexican institute has participated, and to assess their contributions to the primary and secondary prevention of this disease. A search of the Medline database was conducted using the following keywords: gastric/stomach cancer, Mexico. Studies of the Mexican population were selected in which at least one Mexican Institute had participated and where the findings could support public policy proposals directed towards the primary or secondary prevention of gastric cancer. Of the 148 studies found in the Medline database, 100 were discarded and 48 were reviewed. According to the analysis presented, these studies were classified as: epidemiology of gastric cancer (5/48); risk factors and protectors relating to gastric cancer (9/48); relationship between Helicobacter pylori and pathologies associated with gastric cancer and the development of the disease (16/48); relationship between the Epstein-Barr virus and pathologies associated with gastric cancer and the development of the disease (3/48); molecular markers for the development of diseases associated with gastric cancer and gastric cancer (15/48). Mexico requires a program for the prevention and control of gastric cancer based on national health indicators. This should be produced by a multidisciplinary committee of experts who can propose actions that are relevant in the current national context. The few studies of gastric cancer conducted on the Mexican population in national institutes highlight the poor connection that currently exists between the scientific community and the health sector in terms of resolving this health issue. Public policies for health research should support projects with findings that can be translated into benefits for the population. This review serves to identify national research groups studying gastric cancer in the Mexican

  14. A survey of etiologic hypotheses among testicular cancer researchers

    DEFF Research Database (Denmark)

    Stang, A; Trabert, B; Rusner, C


    the plausibility of the suggested etiologic hypotheses on a scale of 1 (very implausible) to 10 (very plausible). This report describes the methodology of the survey, the score distributions by individual hypotheses, hypothesis group, and the participants' major research fields, and discuss the hypotheses......Basic research results can provide new ideas and hypotheses to be examined in epidemiological studies. We conducted a survey among testicular cancer researchers on hypotheses concerning the etiology of this malignancy. All researchers on the mailing list of Copenhagen Testis Cancer Workshops...

  15. A comparison of cancer burden and research spending reveals discrepancies in the distribution of research funding

    Directory of Open Access Journals (Sweden)

    Carter Ashley JR


    Full Text Available Abstract Background Ideally, the distribution of research funding for different types of cancer should be equitable with respect to the societal burden each type of cancer imposes. These burdens can be estimated in a variety of ways; “Years of Life Lost” (YLL measures the severity of death in regard to the age it occurs, "Disability-Adjusted Life-Years" (DALY estimates the effects of non-lethal disabilities incurred by disease and economic metrics focus on the losses to tax revenue, productivity or direct medical expenses. We compared research funding from the National Cancer Institute (NCI to a variety of burden metrics for the most common types of cancer to identify mismatches between spending and societal burden. Methods Research funding levels were obtained from the NCI website and information for societal health and economic burdens were collected from government databases and published reports. We calculated the funding levels per unit burden for a wide range of different cancers and burden metrics and compared these values to identify discrepancies. Results Our analysis reveals a considerable mismatch between funding levels and burden. Some cancers are funded at levels far higher than their relative burden suggests (breast cancer, prostate cancer, and leukemia while other cancers appear underfunded (bladder, esophageal, liver, oral, pancreatic, stomach, and uterine cancers. Conclusions These discrepancies indicate that an improved method of health care research funding allocation should be investigated to better match funding levels to societal burden.

  16. English Vocabulary Instruction for English Learners (United States)

    Manyak, Patrick C.; Bauer, Eurydice Bouchereau


    In this column Manyak and Bauer summarize key research addressing the English vocabulary development of English learners (ELs) and distill implications for instructional practice. First, the authors discuss several key studies that demonstrate the limitation of many ELs' English vocabulary knowledge and the negative impact of this limitation on…

  17. Integrating China English into College English Teaching

    Institute of Scientific and Technical Information of China (English)



    China English does exist, which is reconfirmed by salient linguistic features illustrated and documented by many research scholars. This paper explores some pedagogical implications addressing the issue of integrating China English into college English teaching to enhance learners' confidence and competence in cross-cultural communication.

  18. Nutrigenetics in cancer research--folate metabolism and colorectal cancer. (United States)

    Ulrich, Cornelia M


    The B vitamin folate is essential for one-carbon transfer reactions, including those related to the methylation of DNA or other substrates and nucleotide synthesis. Epidemiologic and experimental studies implicate low-folate intakes in elevated risk of colorectal neoplasia and suggest that biologic mechanisms underlying this relation include disturbances in DNA methylation patterns or adverse effects on DNA synthesis and repair. With the completion of the Human Genome Project, a vast amount of data on inherited genetic variability has become available. This genetic information can be used in studies of molecular epidemiology to provide information on multiple aspects of folate metabolism. First, studies linking polymorphisms in folate metabolism to an altered risk of cancer provide evidence for a causal link between this pathway and colorectal carcinogenesis. Second, studies on genetic characteristics can help clarify whether certain individuals may benefit from higher or lower intakes of folate or nutrients relevant to folate metabolism. Third, studies on genetic polymorphisms can generate hypotheses regarding possible biologic mechanisms that connect this pathway to carcinogenesis. Last, genetic variability in folate metabolism may predict survival after a cancer diagnosis, possibly via pharmacogenetic effects. To solve the puzzle of the folate-cancer relation, a transdisciplinary approach is needed that integrates knowledge from epidemiology, clinical studies, experimental nutrition, and mathematical modeling. This review illustrates knowledge that can be gained from molecular epidemiology in the context of nutrigenetics, and the questions that this approach can answer or raise.

  19. Application research of constructivism in the teaching of undergraduate English multimedia network

    Institute of Scientific and Technical Information of China (English)



    Constructivism is the frontier theory of cognitive psychology,constructivism has important and far-reaching influence to the college English teaching reform which is vigorously implemented in our country.Based on the introduce of constructivism theory,and the analysis of the college English multimedia network teaching status quo in present undergraduate course colleges and universities,this paper put forwards relevant suggestions on how to use constructivism theory in college English multimedia network teaching.

  20. Research on Tactics of English Teaching to College Students by Modern Media Technology


    Zhou Gang


    Modern colleges are faced with the dual pressures of university reform and international competition, how to overcome difficulties, to play the role of modern English teaching in colleges and colleges to enhance the core competitiveness of colleges, colleges and colleges modern English teaching problems to be solved. Based on the current situation of modern colleges in the premise of the Modern media platform fully demonstrated the characteristics and viability of the Modern media English tea...

  1. Brain Cancer in Workers Employed at a Laboratory Research Facility.

    Directory of Open Access Journals (Sweden)

    James J Collins

    Full Text Available An earlier study of research facility workers found more brain cancer deaths than expected, but no workplace exposures were implicated.Adding four additional years of vital-status follow-up, we reassessed the risk of death from brain cancer in the same workforce, including 5,284 workers employed between 1963, when the facility opened, and 2007. We compared the work histories of the brain cancer decedents in relationship to when they died and their ages at death.As in most other studies of laboratory and research workers, we found low rates of total mortality, total cancers, accidents, suicides, and chronic conditions such as heart disease and diabetes. We found no new brain cancer deaths in the four years of additional follow-up. Our best estimate of the brain cancer standardized mortality ratio (SMR was 1.32 (95% confidence interval [95% CI] 0.66-2.37, but the SMR might have been as high as 1.69. Deaths from benign brain tumors and other non-malignant diseases of the nervous system were at or below expected levels.With the addition of four more years of follow-up and in the absence of any new brain cancers, the updated estimate of the risk of brain cancer death is smaller than in the original study. There was no consistent pattern among the work histories of decedents that indicated a common causative exposure.

  2. Advances in cancer research. Volume 41

    Energy Technology Data Exchange (ETDEWEB)

    Klein, G.; Weinhouse, S.


    This book contains seven chapters. They are: The Epidemiology of Diet and Cancer; Molecular Aspects of Immunoglobin Expression by Human B Cell Leukemias and Lymphomas; Mouse Mammary Tumor Virus: Transcriptional Control and Involvement in Tumorigenesis; Dominant Susceptibility to Cancer in Man; Multiple Myeloma; Waldenstreom's Macroglobulinemia, and Benign Monoclonal Gammopathy: Characteristics of the B Cell Clone, Immunoregulatory Cell Populations and Clinical Implications; Idiotype Network Interactions in Tumor Immunity; and Chromosomal Location of Immunoglobulin Genes: Partial Mapping of these Genes in the Rabbit and Comparison with Ig Genes Carrying Chromosomes of Man and Mouse.

  3. Research Paradigm Shifts and Their Bibliographic Consequences for English Composition Researchers. (United States)

    Scott, Patrick

    There are four problems in modern composition bibliography that result directly from the continuing research paradigm instability in the field. The first problem is that of definition. Composition is a hybrid, practical sort of field, with very ill-defined and shifting boundaries. The recent extension of composition from "formal writing…

  4. Pancreatic Cancer: Updates on Translational Research and Future Applications

    Directory of Open Access Journals (Sweden)

    Evangelos G Sarris


    Full Text Available Pancreatic cancer is one of the most lethal malignancies with a mortality rate almost equal to its incidence. It is ranked as the fourth leading cause of cancer-related deaths in the United States, and despite intensive basic and clinical research over the last few years, the survival benefit for the majority of patients with pancreatic cancer is still disappointing. Due to the absence of specific symptoms and the lack of early detection tests, pancreatic cancer is usually diagnosed at an advanced inoperrable stage and palliative chemotherapy with the purine analogue gemcitabine in combination with the targeted agent erlotinib, remains the mainstay method in the management of these patients. Therefore, there is an imperative need for new findings in the translational research field with prognostic, predictive and therapeutic value. In this paper we summarize five most interesting research abstracts as presented at the 2013 American Society of Clinical Oncology (ASCO Gastrointestinal Cancers Symposium. In particular, we focus on Abstract #141 which investigates the interaction between liver and pancreatic organ damage in patients with pancreatic cancer and the potential contribution of the patatin-like phospholipase domain containing 3 (PNPLA3 gene variation in pancreatic cancer development and on Abstract #149, in which, the prognostic and predictive role of SWI/SNF complex, a chromatin-remodeling complex, is examined. The key role of pharmacogenomics, in terms of predicting response and resistance to chemotherapy in pancreatic cancer patients, is analyzed in Abstract #142 and the contribution of circulating tumor cell detection in the early diagnosis of pancreatic cancer, allowing the avoidance of more invasive procedures like EUS-FNA, is discussed in Abstract #157. Lastly, in Abstract #164, the diagnostic utility of YKL-40 and IL-6 in pancreatic cancer patients is investigated.

  5. Epigenetic research in cancer epidemiology: trends, opportunities, and challenges. (United States)

    Verma, Mukesh; Rogers, Scott; Divi, Rao L; Schully, Sheri D; Nelson, Stefanie; Joseph Su, L; Ross, Sharon A; Pilch, Susan; Winn, Deborah M; Khoury, Muin J


    Epigenetics is emerging as an important field in cancer epidemiology that promises to provide insights into gene regulation and facilitate cancer control throughout the cancer care continuum. Increasingly, investigators are incorporating epigenetic analysis into the studies of etiology and outcomes. To understand current progress and trends in the inclusion of epigenetics in cancer epidemiology, we evaluated the published literature and the National Cancer Institute (NCI)-supported research grant awards in this field to identify trends in epigenetics research. We present a summary of the epidemiologic studies in NCI's grant portfolio (from January 2005 through December 2012) and in the scientific literature published during the same period, irrespective of support from the NCI. Blood cells and tumor tissue were the most commonly used biospecimens in these studies, although buccal cells, cervical cells, sputum, and stool samples were also used. DNA methylation profiling was the focus of the majority of studies, but several studies also measured microRNA profiles. We illustrate here the current status of epidemiologic studies that are evaluating epigenetic changes in large populations. The incorporation of epigenomic assessments in cancer epidemiology studies has and is likely to continue to provide important insights into the field of cancer research.

  6. From English to Chinese, Japanese, and Russian: extending research visibility with language translations of a conference slide presentation (United States)

    Hoffecker, Lilian; Abbey, Dana


    Objective The research demonstrates that a conference slide presentation translated into non-English languages reaches significantly larger and different audiences than an English presentation alone. Methods The slides of a presentation from the Medical Library Association annual meeting were translated from English to Chinese, Japanese, and Russian and posted along with the English version to SlideShare, an open slide-hosting website. View counts, traffic sources, and geographic origins of the traffic for each language version were tracked over a twenty-two-month period. Results Total view counts for all 4 language versions amounted to 3,357 views, with the Chinese version accounting for 71% of the total views. The trends in view counts over time for the Japanese, Russian, and English versions were similar, with high interest at the beginning and a rapid drop and low level of viewing activity thereafter. The pattern of view counts for the Chinese version departed considerably from the other language versions, with very low activity at the beginning but a sharp rise 10 months later. This increase in activity was related to access to the presentations via a Taiwanese website that embedded the SlideShare website code. Conclusions Language translation can be a difficult and time-consuming task. However, translation of a conference slide presentation with limited text is an achievable activity and engages an international audience for information that is often not noticed or lost. Although English is by far the primary language of science and other disciplines, it is not necessarily the first or preferred language of global researchers. By offering appropriate language versions, the authors of presentations can expand the reach of their work. PMID:28096746

  7. Promising Tools in Prostate Cancer Research

    DEFF Research Database (Denmark)

    Bonomo, Silvia; Hansen, Cecilie H; Petrunak, Elyse M


    Cytochrome P450 17A1 (CYP17A1) is an important target in the treatment of prostate cancer because it produces androgens required for tumour growth. The FDA has approved only one CYP17A1 inhibitor, abiraterone, which contains a steroidal scaffold similar to the endogenous CYP17A1 substrates...

  8. Evidence and research in rectal cancer.

    NARCIS (Netherlands)

    Valentini, V.; Beets-Tan, R.; Borras, J.M.; Krivokapic, Z.; Leer, J.W.H.; Pahlman, L.; Rodel, C.; Schmoll, H.J.; Scott, N.; Velde, C.V.; Verfaillie, C.


    The main evidences of epidemiology, diagnostic imaging, pathology, surgery, radiotherapy, chemotherapy and follow-up are reviewed to optimize the routine treatment of rectal cancer according to a multidisciplinary approach. This paper reports on the knowledge shared between different specialists inv

  9. Testicular Cancer Survivorship : Research Strategies and Recommendations

    NARCIS (Netherlands)

    Travis, Lois B.; Beard, Clair; Allan, James M.; Dahl, Alv A.; Feldman, Darren R.; Oldenburg, Jan; Daugaard, Gedske; Kelly, Jennifer L.; Dolan, M. Eileen; Hannigan, Robyn; Constine, Louis S.; Oeffinger, Kevin C.; Okunieff, Paul; Armstrong, Greg; Wiljer, David; Miller, Robert C.; Gietema, Jourik A.; van Leeuwen, Flora E.; Williams, Jacqueline P.; Nichols, Craig R.; Einhorn, Lawrence H.; Fossa, Sophie D.


    Testicular cancer represents the most curable solid tumor, with a 10-year survival rate of more than 95%. Given the young average age at diagnosis, it is estimated that effective treatment approaches, in particular, platinum-based chemotherapy, have resulted in an average gain of several decades of

  10. Healthy Eating for Life English as a second language curriculum: primary outcomes from a nutrition education intervention targeting cancer risk reduction. (United States)

    Duncan, Lindsay R; Martinez, Josefa L; Rivers, Susan E; Latimer, Amy E; Bertoli, Michelle C; Domingo, Samantha; Salovey, Peter


    We conducted a pre-post feasibility trial of Healthy Eating for Life, a theory-based, multimedia English as a second language curriculum that integrates content about healthy nutrition into an English language learning program to decrease cancer health disparities. Teachers in 20 English as a second language classrooms delivered Healthy Eating for Life to 286 adult English as a second language students over one semester. Postintervention data are available for 227 students. The results indicated that Healthy Eating for Life is effective for increasing fruit and vegetable intake as well as knowledge, action planning, and coping planning related to healthy eating. Participants also achieved higher reading scores compared to the state average.

  11. MicroRNAs – important molecules in lung cancer research

    Directory of Open Access Journals (Sweden)

    Petra eLeidinger


    Full Text Available MicroRNAs (miRNA are important regulators of gene expression. They are involved in many physiological processes ensuring the cellular homeostasis of human cells. Alterations of the miRNA expression have increasingly been associated with pathophysiological changes of cancer cells making miRNAs currently to one of the most analyzed molecules in cancer research. Here we provide an overview of miRNAs in lung cancer. Specifically, we address biological functions of miRNAs in lung cancer cells, miRNA signatures generated from tumor tissue and from patients’ body fluids, the potential of miRNAs as diagnostic and prognostic biomarker for lung cancer, and its role as therapeutical target.

  12. English Water Meadows: historic relics or focus for environmental management and inter-disciplinary research? (United States)

    Cook, Hadrian


    Irrigated water meadows are found across Europe, from southern Scandinavia to Spain and in the Alpine regions and Italy. While the practice of engineering 'floated' meadow land for deliberate irrigation on hillsides and floodplains is widespread and ancient, since about 1600 AD the practice was widely adopted on floodplains in southern England where they improved the timing and productivity of grazing land and produced hay crops. They also became a part of English consciousness through art and literature. To some, water meadows are a relic of an agrarian past, to others they are the object of a range of foci for conservation, education, sustainable grass production, community engagement and recent research suggests water returned from meadow irrigation is beneficial to river water quality. Historically floodplain 'bedwork' water meadows grew from, and were integral in, the farming system of 'Wessex' involving sheep which produced dung for arable land and later supporting dairy and beef production, as well as hay. Where systems remain, this is largely due to the whim of individuals, the outcome of agri-environmental schemes. Water meadows may be managed by public, voluntary or private sector bodies. What is needed is a fresh look at how land owners, or communities, might micro-target them for heritage, habitat and grassland management. There are therefore interesting questions concerning their future: Who might invest in their restoration and maintenance? How might they be integrated into commercial farming? Are they of sufficient interest to restore en masse to become (once more) a major feature of the English chalk stream valleys? Do they provide a way into academic and public perception, combining environmental science, history, cultural heritage and environmental management? How might restoration and management become vehicles for public engagement? While each of these questions represents a major topic for discussion, this paper is an attempt to consolidate

  13. European Union Students Studying in English Higher Education Institutions. DIUS Research Report 08-09 (United States)

    Morris, Marian; Rutt, Simon


    This study aimed to identify the pathways, intentions and relevant perceptions of (non-UK) European Union (EU) students entering English higher education. It sought to identify why students wished to obtain an English HE qualification, their attitudes towards the uptake and repayment of tuition fee loans and their future career plans. Drawing on…

  14. English Language Learners: Research on the Effects of Reclassification. Information Capsule. Volume 1506 (United States)

    Blazer, Christie


    Since the 1970s, federal civil rights legislation has mandated that school districts identify English language learners (ELLs) and provide them with services that allow them to fully participate in the educational system. The intent of this requirement is to ensure educational equity for students whose limited knowledge of English prevents them…

  15. A Research on Students' Needs for Follow-Up Curriculum of College English (United States)

    Jin, Jie; Liu, Hengying; Zhang, Yan


    Increased universities and colleges offer the undergraduates with more follow-up courses with the further reform in college English education in China. An investigation on self-evaluation, difficulty, and willingness of undergraduates in learning English further was made in order to design more appropriate and adaptable follow-up courses. This…

  16. A Research on English Educational Problems among Intermediates in Middle School

    Institute of Scientific and Technical Information of China (English)



    This paper mainly centers on the neglecting parts of English intermediates in middle school and presents their existing study problems. According to intermediates' characters and learning motivation, I will reveal reasons of these problems and come up with effective strategies from two aspects of English teachers and students.

  17. The Research of Difference between Boys and Girls during English Study

    Institute of Scientific and Technical Information of China (English)



    With China's opening up and joining the World Trade Organization, more and more people are learning English. English study is very important for the learners, which involves a lot of factors, among which the learner's own factor is the most direct and main factor. In English teaching, we shouldn’t just pay our attention to the regular teaching principle of teaching stu-dents in accordance with their aptitude, and turn a blind eye to the non-intellectual factors of the learners. This thesis analyzes the differences and their reasons, and then puts forward some relevant countermeasures for eliminating the differences in English learning between boys and girls, in the hope of promoting them to make progress together in English study.

  18. Acupuncture Research at Memorial Sloan Kettering Cancer Center. (United States)

    Javdan, Bahar; Cassileth, Barrie


    Acupuncture may help treat specific cancer-related symptoms. Here, we summarize our clinical trials that sought to determine acupuncture's role in managing cancer-related symptoms. Trials have been conducted to determine acupuncture's ability to mitigate cancer-related symptoms including dyspnea, fatigue, xerostomia, lymphedema, hot flashes, postoperative ileus, pain and dysfunction after neck dissection, and postthoracotomy pain. Published studies indicate that acupuncture versus placebo acupuncture failed to reduce cancer-related dyspnea. Both true and sham acupuncture alleviated fatigue slightly, but no significant differences between groups emerged. Compared with sham acupuncture, our research showed that acupuncture significantly improved saliva production in patients with xerostomia and significantly reduced lymphedema patients' arm circumference in a pilot study. However, acupuncture failed to significantly reduce hot flashes and was no more successful than sham acupuncture in reducing postoperative ileus. Significant reductions in pain and dysfunction occurred in cancer patients after neck dissection. In a feasibility study, acupuncture was found to be acceptable to lung cancer patients and did not interfere with standard postoperative care. In summary, acupuncture is a potential candidate for the treatment of some important cancer-related symptoms. Large clinical trials and research to investigate mechanistic pathways are warranted.

  19. Summer Prostate Cancer Research Training Program (United States)


    addition, contributed patients for study of circulating tumor cells before and after prostatectomy, and, more recently, helped to develop a prospective...gynecologic cancers and gestational disorders such as pre-eclampsia and pre-term birth. PLAC1 is expressed in numerous tissues during fetal development...exclusively in placental trophoblasts in reproductive age women and in gynecologic tumors. It is, thus, the only known example of an onco- fetal

  20. Network for Translational Research - Cancer Imaging Program (United States)

    Cooperative agreement (U54) awards to establish Specialized Research Resource Centers that will participate as members of a network of inter-disciplinary, inter-institutional research teams for the purpose of supporting translational research in optical imaging and/or spectroscopy in vivo, with an emphasis on multiple modalities.

  1. Cancer Prevention and Control Research Manpower Development (United States)


    34 : problem areas such as self-care (Dodd & Dibble, lishing a multisite team to conduct research with a ’r 1993), communication ( Northouse & Wortman, 1990...Guidelines for collaborative research. Applied Nurs- Northouse , L.L., & Wortman, C.B. (1990). Models of helping and cop- ing Research, 2, 150-183. ing in

  2. Long-term oceanographic and ecological research in the Western English Channel. (United States)

    Southward, Alan J; Langmead, Olivia; Hardman-Mountford, Nicholas J; Aiken, James; Boalch, Gerald T; Dando, Paul R; Genner, Martin J; Joint, Ian; Kendall, Michael A; Halliday, Nicholas C; Harris, Roger P; Leaper, Rebecca; Mieszkowska, Nova; Pingree, Robin D; Richardson, Anthony J; Sims, David W; Smith, Tania; Walne, Anthony W; Hawkins, Stephen J


    Long-term research in the western English Channel, undertaken by the marine laboratories in Plymouth, is described and details of survey methods, sites, and time series given in this chapter. Major findings are summarized and their limitations outlined. Current research, with recent reestablishment and expansion of many sampling programmes, is presented, and possible future approaches are indicated. These unique long-term data sets provide an environmental baseline for predicting complex ecological responses to local, regional, and global environmental change. Between 1888 and the present, investigations have been carried out into the physical, chemical, and biological components (ranging from plankton and fish to benthic and intertidal assemblages) of the western English Channel ecosystem. The Marine Biological Association of the United Kingdom has performed the main body of these observations. More recent contributions come from the Continuous Plankton Recorder Survey, now the Sir Alister Hardy Foundation for Ocean Science, dating from 1957; the Institute for Marine Environmental Research, from 1974 to 1987; and the Plymouth Marine Laboratory, which was formed by amalgamation of the Institute for Marine Environmental Research and part of the Marine Biological Association, from 1988. Together, these contributions constitute a unique data series-one of the longest and most comprehensive samplings of environmental and marine biological variables in the world. Since the termination of many of these time series in 1987-1988 during a reorganisation of UK marine research, there has been a resurgence of interest in long-term environmental change. Many programmes have been restarted and expanded with support from several agencies. The observations span significant periods of warming (1921-1961; 1985-present) and cooling (1962-1980). During these periods of change, the abundance of key species underwent dramatic shifts. The first period of warming saw changes in

  3. Multimorbidity and cancer outcomes: a need for more research

    Directory of Open Access Journals (Sweden)

    Sørensen HT


    Full Text Available Henrik Toft Sørensen Editor in Chief Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkCancer incidence increases with age, and about 43% of men and 30% of women aged 65 will develop cancer in their remaining lifetimes.1 The global population is rapidly aging, and by 2030 about 70% of cancer in, for example, the US, will be diagnosed in older patients.2 Fortunately, cancer survival has improved and 5-year survival exceeds 80% for many common cancers.3 As a result of these two complementary trends, the population of cancer survivors is growing at a rate of almost 2% per year.4As comorbidities accumulate with age, the number of patients with multimorbidity, ie, the coexistence of several chronic diseases, is increasing dramatically.5 In the US, about 80% of Medicare funds are spent on patients with four or more chronic conditions. Multimorbidity is associated with mortality, disability, low functional status, and risks of adverse drug events.6,7Clinical and epidemiological research on cancer prognosis has mainly focused on cancers in isolation, ignoring the impact of comorbidity and co-medication on the risk of complications and mortality. Comorbidity is a medical condition that exists at the time of diagnosis of the cancer or later, but which is not a consequence of the cancer itself.8Comorbidity is common in cancer patients, who often have adverse lifestyle factors such as alcohol use, obesity, and smoking, which cause other chronic diseases. Thus, many cancer patients have chronic disorders such as chronic obstructive pulmonary disease, acute myocardial infarction, stroke, metabolic syndrome, and osteoporosis.9–13 With the growing population of elderly patients with cancer and other chronic diseases, modern medicine will need to address multiple medical problems at once, focusing on mortality, treatment complications, quality of life, and implications for screening.7,14 In this issue of Clinical Epidemiology

  4. Cancer immunotherapy out of the gate: the 22nd annual Cancer Research Institute International Immunotherapy Symposium. (United States)

    Tontonoz, Matthew; Gee, Connie E


    The 22nd annual Cancer Research Institute (CRI) International Immunotherapy Symposium was held from October 5-8, 2014, in New York City. Titled "Cancer Immunotherapy: Out of the Gate," the symposium began with a Cancer Immunotherapy Consortium satellite meeting focused on issues in immunotherapy drug development, followed by five speaker sessions and a poster session devoted to basic and clinical cancer immunology research. The second annual William B. Coley lecture was delivered by Lieping Chen, one of the four recipients of the 2014 William B. Coley Award for Distinguished Research in Tumor Immunology; the other three recipients were Gordon Freeman, Tasuku Honjo, and Arlene Sharpe. Prominent themes of the conference were the use of genomic technologies to identify neoantigens and the emergence of new immune modulatory molecules, beyond CTLA-4 and PD-1/PD-L1, as new therapeutic targets for immunotherapy.

  5. Integrating Heterogeneous Biomedical Data for Cancer Research: the CARPEM infrastructure



    Summary Cancer research involves numerous disciplines. The multiplicity of data sources and their heterogeneous nature render the integration and the exploration of the data more and more complex. Translational research platforms are a promising way to assist scientists in these tasks. In this article, we identify a set of scientific and technical principles needed to build a translational research platform compatible with ethical requirements, data protection and data-integration problems. W...

  6. Persistence by Successful and Nonsuccessful Remedial and Nonremedial English and English as a Second Language Students: A Longitudinal Study. Research Report #65. (United States)

    Kangas, Jon Alan; Reichelderfer, Nancy

    A study was conducted at Evergreen Valley College (EVC) to examine the effects of remedial English and English as a Second Language (ESL) instruction on student persistence. All new fall 1982 day students without prior college experience (N=1,264) were divided into three groups: English students, ESL students, and students who took no placement…

  7. A Preliminary Research on Errors in the English Translation of《The Analects of Confucious》)by James Legge%A Preliminary Research on Errors in the English Translation 0f《The Analects of Confucious》)by James Legge

    Institute of Scientific and Technical Information of China (English)

    LIU xia


    (The Analects of Confucious)is hard to undersmnd even to Chinese,the foreign translators with different culturetions although his translation of The Analects in 1861 is regarded as the first authorized English version continuing untilthis day.The aim to analyze the errors in James Legge'S version is to show that "misundeTstanding many sometimesprove to be extraordinarily valuable in research field in that misunderstanding reflects the translator's misconceiving ofanother culture.the blockade in cultural exchange".

  8. 探究小学英语课堂%The Research of Primary English Class

    Institute of Scientific and Technical Information of China (English)



    随着我国教育事业的快速发展,英语学科的地位不断提高。英语作为小学生的必修学科,是影响学生语言思维的重要学科。小学英语教学活动,对于小学生英语学习观的建立都有重要的作用。从小学英语的教学内容以及教学现状出发,分析了关于小学英语教学的几种方法,希望以此促进小学英语课堂教学效率的提高。%With the rapid development of China’s education, the continuous improvement of the status of English subjects. English as a compulsory subject for primary students is an important discipline to affect the student’s language of thought. Primary English teaching activities for the establishment of primary school English learning concept has an important role. Beginning from the primary English ’s teaching content and teaching situation,analyzes several methods in primary school English teaching, and hoping to promote school English teaching efficiency.

  9. Public figure announcements about cancer and opportunities for cancer communication: a review and research agenda. (United States)

    Noar, Seth M; Willoughby, Jessica Fitts; Myrick, Jessica Gall; Brown, Jennifer


    Announcements by public figures and celebrities about cancer diagnosis or death represent significant events in public life. But what are the substantive effects of such events, if any? The purpose of this article is to systematically review studies that examined the impact of public figure cancer announcements on cancer-oriented outcomes. Using comprehensive search procedures, we identified k = 19 studies that examined 11 distinct public figures. The most commonly studied public figures were Jade Goody, Kylie Minogue, Nancy Reagan, and Steve Jobs, with the most common cancers studied being breast (53%), cervical (21%), and pancreatic (21%) cancer. Most studies assessed multiple outcome variables, including behavioral outcomes (k = 15), media coverage (k = 10), information seeking (k = 8), cancer incidence (k = 3), and interpersonal communication (k = 2). Results fairly consistently indicated that cancer announcements from public figures had meaningful effects on many, if not most, of these outcome variables. While such events essentially act as naturally occurring interventions, the effects tend to be relatively short term. Gaps in this literature include few contemporary studies of high-profile public figures in the United States and a general lack of theory-based research. Directions for future research as well as implications for cancer communication and prevention are discussed.

  10. Research on Promote the Attendance of Senior Students in English Class

    Institute of Scientific and Technical Information of China (English)



    In traditional English class of China, the relationship between teacher and students is one-way communication. As a result, positive attendance in senior English class is not common. It is important to develop students' automatic learning and coop⁃eration learning abilities. However, the particularities of senior students in psychology and the background of college entrance ex⁃amination block the way of traditional teaching reform. From these aspects, this thesis comes up with corresponding advices to promote the attendance of senior English class.

  11. A survey of etiologic hypotheses among testicular cancer researchers. (United States)

    Stang, A; Trabert, B; Rusner, C; Poole, C; Almstrup, K; Rajpert-De Meyts, E; McGlynn, K A


    Basic research results can provide new ideas and hypotheses to be examined in epidemiological studies. We conducted a survey among testicular cancer researchers on hypotheses concerning the etiology of this malignancy. All researchers on the mailing list of Copenhagen Testis Cancer Workshops and corresponding authors of PubMed-indexed articles identified by the search term 'testicular cancer' and published within 10 years (in total 2750 recipients) were invited to respond to an e-mail-based survey. Participants of the 8th Copenhagen Testis Cancer Workshop in May 2014 were subsequently asked to rate the plausibility of the suggested etiologic hypotheses on a scale of 1 (very implausible) to 10 (very plausible). This report describes the methodology of the survey, the score distributions by individual hypotheses, hypothesis group, and the participants' major research fields, and discuss the hypotheses that scored as most plausible. We also present plans for improving the survey that may be repeated at a next international meeting of experts in testicular cancer. Overall 52 of 99 (53%) registered participants of the 8th Copenhagen Testis Cancer Workshop submitted the plausibility rating form. Fourteen of 27 hypotheses were related to exposures during pregnancy. Hypotheses with the highest mean plausibility ratings were either related to pre-natal exposures or exposures that might have an effect during pregnancy and in post-natal life. The results of the survey may be helpful for triggering more specific etiologic hypotheses that include factors related to endocrine disruption, DNA damage, inflammation, and nutrition during pregnancy. The survey results may stimulate a multidisciplinary discussion about new etiologic hypotheses of testicular cancer.

  12. Research Donor Program Needs Your Help to Advance Cancer and AIDS Research | Poster (United States)

    NCI at Frederick employees have a unique opportunity to contribute directly to cancer and AIDS research by donating blood, saliva, and other samples through the Research Donor Program (RDP). Donors are compensated for their time, which is typically between 10 and 30 minutes. The RDP, which is administered by Occupational Health Services (OHS), Leidos Biomedical Research, provides samples from healthy donors for use in in vitro research conducted at NCI at Frederick and Fort Detrick. Samples are provided anonymously to researchers.

  13. Frontiers in cancer epidemiology: a challenge to the research community from the Epidemiology and Genomics Research Program at the National Cancer Institute. (United States)

    Khoury, Muin J; Freedman, Andrew N; Gillanders, Elizabeth M; Harvey, Chinonye E; Kaefer, Christie; Reid, Britt C; Rogers, Scott; Schully, Sheri D; Seminara, Daniela; Verma, Mukesh


    The Epidemiology and Genomics Research Program (EGRP) at the National Cancer Institute (NCI) is developing scientific priorities for cancer epidemiology research in the next decade. We would like to engage the research community and other stakeholders in a planning effort that will include a workshop in December 2012 to help shape new foci for cancer epidemiology research. To facilitate the process of defining the future of cancer epidemiology, we invite the research community to join in an ongoing web-based conversation at to develop priorities and the next generation of high-impact studies.

  14. CRISPR-Cas9: from Genome Editing to Cancer Research. (United States)

    Chen, Si; Sun, Heng; Miao, Kai; Deng, Chu-Xia


    Cancer development is a multistep process triggered by innate and acquired mutations, which cause the functional abnormality and determine the initiation and progression of tumorigenesis. Gene editing is a widely used engineering tool for generating mutations that enhance tumorigenesis. The recent developed clustered regularly interspaced short palindromic repeats-CRISPR-associated 9 (CRISPR-Cas9) system renews the genome editing approach into a more convenient and efficient way. By rapidly introducing genetic modifications in cell lines, organs and animals, CRISPR-Cas9 system extends the gene editing into whole genome screening, both in loss-of-function and gain-of-function manners. Meanwhile, the system accelerates the establishment of animal cancer models, promoting in vivo studies for cancer research. Furthermore, CRISPR-Cas9 system is modified into diverse innovative tools for observing the dynamic bioprocesses in cancer studies, such as image tracing for targeted DNA, regulation of transcription activation or repression. Here, we view recent technical advances in the application of CRISPR-Cas9 system in cancer genetics, large-scale cancer driver gene hunting, animal cancer modeling and functional studies.

  15. 国内中小学英语家庭作业研究综述%Review of English Homework Research in Primary and Secondary Schooks in China

    Institute of Scientific and Technical Information of China (English)

    贾炜茵; 关世民


    Researches on English homework in primary and secondary school in China mainly involve five parts: quantity and time of English homework, function of English homework, content and types of English homework, optimal strategies of English homework design, evaluation and feedback of English homework. These researches are a positive inspiration and provide a good reference for the study of English teaching in primary and secondary school. However, there still exist many problems in these studies. For example, there are more researches focusing on speciifc issues, but the researches and construc tion of basic theory of homework are not enough; there are more experience summary and theorefical researches, but quantitative reseaches are not enough.%国内对中小学英语家庭作业的研究涉及英语家庭作业的量、时间、功能、内容与类型、优化设计与布置和评价与反馈等研究。这些研究对中小学英语教学有积极的启发和借鉴意义,但也存在对具体问题的研究较多,对作业基本理论的研究和建构薄弱;经验总结和思辨研究多,量化研究少的问题。

  16. Advanced Research on Circulating Tumor Cells in Lung Cancer

    Directory of Open Access Journals (Sweden)

    Hui LI


    Full Text Available Lung cancer is the malignant disease with the highest rate in terms of incidence and mortality in China. Early diagnosis and timely monitoring tumor recurrence and metastasis are extremely important for improving 5-year survival rate of lung cancer patients. Circulating tumor cells (CTCs, as a "liquid biopsy specimens” for the primary tumor, provide the possibility to perform real-time, non-invasive histological identification for lung cancer patients. The detection of CTCs contributes to early diagnosis, surveillance of tumor recurrence and metastasis, and prediction of therapeutic efficacy and prognosis. Furthermore, CTCs-dependent detection emerges as a new approach for molecularly pathologic examination, study of molecular mechanisms involved in drug resistance, and resolution for tumor heterogeneity. This study reviewed the recent progress of CTCs in lung cancer research field.

  17. Research advances in traditional Chinese medicine syndromes in cancer patients. (United States)

    Ji, Qing; Luo, Yun-quan; Wang, Wen-hai; Liu, Xuan; Li, Qi; Su, Shi-bing


    Traditional Chinese medicine (TCM) syndrome, also known as TCM ZHENG or TCM pattern, is an integral and essential part of TCM theory that helps to guide the design of individualized treatments. A TCM syndrome, in essence, is a characteristic profile of all clinical manifestations in one patient that can be readily identified by a TCM practitioner. In this article, the authors reviewed the presentations of TCM syndromes in seven common malignancies (liver, lung, gastric, breast, colorectal, pancreatic and esophageal cancers), the objectivity and the standardization of TCM syndrome differentiation, the evaluation of TCM syndrome modeling in cancer research, and syndrome differentiation-guided TCM treatment of cancers. A better understanding of TCM syndrome theory, as well as its potential biological basis, may contribute greatly to the clinical TCM diagnosis and the treatment of cancer.

  18. Researchers Identify Early Sign of Pancreatic Cancer (United States)

    ... be detected before the disease is diagnosed.” The researchers utilized blood samples collected years earlier from 1,500 people participating in large health-tracking studies. They analyzed the samples for more than ...

  19. A Research on Bilingual Dictionary Based Sentence Alignment for Chinese English Parallel Corpus

    Institute of Scientific and Technical Information of China (English)


    Parallel corpus is of great importance to machine translation, and automatic sentence alignment is the first step towards its processing. This paper puts forward a bilingual dictionary based sentence alignment method for Chinese English parallel corpus, which differs from previous length based algorithm in its knowledge-rich approach. Experimental result shows that this method produces over 93% accuracy with usual English-Chinese dictionaries whose translations cover 31.88%~47.90% of the corpus.

  20. Cancer therapies in HIV cure research

    DEFF Research Database (Denmark)

    Rasmussen, Thomas A; Anderson, Jenny L; Wightman, Fiona;


    PURPOSE OF REVIEW: This article provides an overview of anticancer therapies in various stages of clinical development as potential interventions to target HIV persistence. RECENT FINDINGS: Epigenetic drugs developed for cancer have been investigated in vitro, ex vivo and in clinical trials...... as interventions aimed at reversing HIV latency and depleting the amount of virus that persists on antiretroviral therapy. Treatment with histone deacetylase inhibitors induced HIV expression in patients on antiretroviral therapy but did not reduce the frequency of infected cells. Other interventions that may...... accelerate the decay of latently infected cells, in the presence or absence of latency-reversing therapy, are now being explored. These include apoptosis-promoting agents, nonhistone deacetylase inhibitor compounds to reverse HIV latency and immunotherapy interventions to enhance antiviral immunity...


    Institute of Scientific and Technical Information of China (English)


    With the arrival of the new millennium,the demand fortalented people with both professional knowledge and excellentlanguage abilities is getting stronger and stronger.For business major students,reading is paramount inBusiness English teaching and learning.And their reading abilityis often assessed by a text of reading comprehension.However,from my experience as a college teacher ofBusiness English,I have noticed some problems among studentswho have little knowledge of business.They seem to readBusiness English materials at a slower rate and with lessunderstanding than general English materials.Then there is the question:is Business English reading"simply"a problem of language competence? Or are there anyother more important factors?This article is an investigation into the effect of backgroundknowledge on Business English reading comprehension.Thestudy attempts to assess to what extent L2 readers might beaffected because of their lack of a background schematapresupposed by the author by comparing the test results of twopassages comparable in language lightness or heaviness.Morecomparable passages like these can be used in investigating intothe rival effects of background knowledge and linguisticcompetence.The implications of comprehension theory for L2pedagogy are discussed and suggestions for Business Englishteaching is put forward.

  2. Alliance Against Cancer, the network of Italian cancer centers bridging research and care. (United States)

    De Paoli, Paolo; Ciliberto, Gennaro; Ferrarini, Manlio; Pelicci, PierGiuseppe; Dellabona, Paolo; De Lorenzo, Francesco; Mantovani, Alberto; Musto, Pellegrino; Opocher, Giuseppe; Picci, Piero; Ricciardi, Walter; De Maria, Ruggero


    Alliance Against Cancer (ACC) was established in Rome in 2002 as a consortium of six Italian comprehensive cancer centers (Founders). The aims of ACC were to promote a network among Italian oncologic institutions in order to develop specific, advanced projects in clinical and translational research. During the following years, many additional full and associate members joined ACC, that presently includes the National Institute of Health, 17 research-oriented hospitals, scientific and patient organizations. Furthermore, in the last three years ACC underwent a reorganization process that redesigned the structure, governance and major activities. The present goal of ACC is to achieve high standards of care across Italy, to implement and harmonize principles of modern personalized and precision medicine, by developing cost effective processes and to provide tailored information to cancer patients. We herein summarize some of the major initiatives that ACC is currently developing to reach its goal, including tumor genetic screening programs, establishment of clinical trial programs for cancer patients treated in Italian cancer centers, facilitate their access to innovative drugs under development, improve quality through an European accreditation process (European Organization of Cancer Institutes), and develop international partnerships. In conclusion, ACC is a growing organization, trying to respond to the need of networking in Italy and may contribute significantly to improve the way we face cancer in Europe.

  3. Multi-targeted approach to cancer treatment: an international translational cancer research symposium. (United States)

    Mehta, Kapil; Gandhi, Varsha; Pathak, Sen; Aggarwal, Bharat B; Grover, Rajesh K


    Whether it is chronic myeloid leukemia, ALK-expressing malignancies, or HER2-positive breast cancer, targeted-therapies for treatment of human cancers have shown great promise. However, as they hit a single molecule expressed in neoplastic cells, their use is frequently associated with development of resistance. In cancer cells many signaling pathways operate in parallel, hence the idea of multi-targeted therapy is prevailing. The Society of Translational Cancer Research held its biennial meeting in the capital city of India, Delhi from February 6th through 9th, 2014 to discuss 'Multi-targeted Approach to Treatment of Cancer'. Over 200 scientists, clinicians, trainees, and industry representatives from different countries gathered in Vigyan Bhavan, the hotspot of Delhi for four days to talk and discuss on a variety of topics related to multi-targeted therapeutic approaches. Talks were presented by leaders in the cancer research field from various countries. It became clear from this conference that coupling multiple targeted-agents or using an agent that hits an individual target in several independent locations in the disease-causing pathway(s) may be the best approach to treat different cancers.

  4. Translational genomics in cancer research:converting proifles into personalized cancer medicine

    Institute of Scientific and Technical Information of China (English)

    Lalit Patel; Brittany Parker; Da Yang; Wei Zhang


    Cancer genomics is a rapidly growing discipline in which the genetic molecular basis of malignancy is studied at the scale of whole genomes. While the discipline has been successful with respect to identifying specific oncogenes and tumor suppressors involved in oncogenesis, it is also challenging our approach to managing patients suffering from this deadly disease. Speciifcally cancer genomics is driving clinical oncology to take a more molecular approach to diagnosis, prognostication, and treatment selection. We review here recent work undertaken in cancer genomics with an emphasis on translation of genomic ifndings. Finally, we discuss scientiifc challenges and research opportunities emerging from ifndings derived through analysis of tumors with high-depth sequencing.

  5. Mapping cancer, cardiovascular and malaria research in Brazil

    Directory of Open Access Journals (Sweden)

    P.S. Rodrigues


    Full Text Available This paper presents performance indicators for the Brazilian cancer, cardiovascular and malaria research areas from 1981 to 1995. The data show an increasing number of papers since 1981 and author numbers indicate a continuous growth of the scientific community and suggest an expected impact of scientific activity on biomedical education. The data also characterize cardiovascular research as a well-established area and cancer research as a faster growing consolidating field. The 1989-1994 share of Brazilian articles among world publications shows a growing trend for the cancer (1.61 and cardiovascular (1.59 areas, and a decrease for the malaria area (0.89. The burden of the three diseases on society is contrasted by the small number of consolidated Brazilian research groups, and a questionable balance of thematic activity, especially with regard to malaria. Brazilian periodicals play an important role in increasing the international visibility of science produced in the country. Cancer and cardiovascular research is strongly concentrated in the Southeastern and in Southern regions of Brazil, especially in São Paulo (at least one address from São Paulo in 64.5% of the 962 cancer articles and in 66.9% of the 2250 cardiovascular articles, the second state being Rio de Janeiro with at least one address in 14.1 and 11% of those articles, respectively. Malaria research (468 articles is more evenly distributed across the country, following the pattern of the endemic distribution of the disease. Surveying these national indicator trends can be useful to establish policies in the decision process about health sciences, medical education and public health.

  6. Impact of the Cancer Prevention and Control Research Network: Accelerating the Translation of Research Into Practice. (United States)

    Ribisl, Kurt M; Fernandez, Maria E; Friedman, Daniela B; Hannon, Peggy A; Leeman, Jennifer; Moore, Alexis; Olson, Lindsay; Ory, Marcia; Risendal, Betsy; Sheble, Laura; Taylor, Vicky M; Williams, Rebecca S; Weiner, Bryan J


    The Cancer Prevention and Control Research Network (CPCRN) is a thematic network dedicated to accelerating the adoption of evidence-based cancer prevention and control practices in communities by advancing dissemination and implementation science. Funded by the Centers for Disease Control and Prevention and National Cancer Institute, CPCRN has operated at two levels: Each participating network center conducts research projects with primarily local partners as well as multicenter collaborative research projects with state and national partners. Through multicenter collaboration, thematic networks leverage the expertise, resources, and partnerships of participating centers to conduct research projects collectively that might not be feasible individually. Although multicenter collaboration is often advocated, it is challenging to promote and assess. Using bibliometric network analysis and other graphical methods, this paper describes CPCRN's multicenter publication progression from 2004 to 2014. Searching PubMed, Scopus, and Web of Science in 2014 identified 249 peer-reviewed CPCRN publications involving two or more centers out of 6,534 total. The research and public health impact of these multicenter collaborative projects initiated by CPCRN during that 10-year period were then examined. CPCRN established numerous workgroups around topics such as: 2-1-1, training and technical assistance, colorectal cancer control, federally qualified health centers, cancer survivorship, and human papillomavirus. This paper discusses the challenges that arise in promoting multicenter collaboration and the strategies that CPCRN uses to address those challenges. The lessons learned should broadly interest those seeking to promote multisite collaboration to address public health problems, such as cancer prevention and control.

  7. Prevention and Treatment of Cancer: Hypes and Hopes 6th International Translational Cancer Research Conference. (United States)

    Patel, Prabhudas; Vora, Hemangini; Aggarwal, Bharat B; Gandhi, Varsha; Mehta, Kapil; Pathak, Sen


    Cancer is primarily an "old-age" disease that has an "age-old" history. The overall incidence of cancer is much higher in Western countries, but is rapidly growing in Eastern countries perhaps due to change in life-style. Almost three million studies published to date indicate that cancer is a hyperproliferative disorder that arises from dysregulation of multiple cell signaling pathways. The cancer genome landscape indicates that approximately 140 genes and 12 cell signaling pathways drive almost all cancers. "Targeted therapy," a buzz word in cancer treatment for the past two decades, has provided antibodies, as well as small-molecule inhibitors. These therapies have been successful only in few instances. However, in most cases, minor increase in overall survival has been reported at the cost of huge expense. An alternative strategy is to prevent cancer or to diagnose and treat the disease at an early stage to gain survival benefits. Such interventions are also cost-effective. To address some of these issues, the 6th International Translational Cancer Research Conference was held during February 4-7th, 2016, in Ahmedabad, Gujarat, India; the homeland of Mahatma Gandhi. This conference was focused on utilizing multidisciplinary approaches for prevention and early treatment that would likely simultaneously or sequentially target many key pathways. Several distinguished speakers were invited from around the world. This article highlights primary features of this conference.

  8. About the Nutritional Science Research Group | Division of Cancer Prevention (United States)

    The Nutritional Science Research Group (NSRG) promotes and supports studies establishing a comprehensive understanding of the precise role of diet and food components in modulating cancer risk and tumor cell behavior. This focus includes approaches to characterize molecular targets and variability in individual responses to nutrients and dietary patterns. |

  9. Mexican breast cancer research output, 2003-2012. (United States)

    Perez-Santos, Jose Luis Martin; Anaya-Ruiz, Maricruz


    The objetive of this study was to explore a bibliometric approach to quantitatively assess current research trends with regard to breast cancer in Mexico. Articles were analyzed by scientific output and research performances of individuals, institutes, and collaborative countries with Mexico. Data were retrieved from the Web of Science database from 2003 to 2012; this was searched using different terms related to breast cancer, including "breast cancer", "mammary ductal carcinoma" and "breast tumour". Data were then extracted from each file, transferred to Excel charts and visualised as diagrams. A total of 256 articles were retrieved. The institutions with the majority of publications were the National Autonomous University of Mexico (22.3%), the National Institute of Cancerology (21.9%), and Social Security Mexican Institute (20.3%); clinical observation studies were the dominant investigation type (64%), and the main types of research were metabolics (24.2%) and pathology (21.5%). This article demonstrates the usefulness of bibliometrics to address key evaluation questions and to establish priorities, define future areas of research, and develop breast cancer control strategies in Mexico.

  10. Tumor Cold Ischemia - Office of Cancer Clinical Proteomics Research (United States)

    In a recently published manuscript in the journal of Molecular and Cellular Proteomics, researchers from the National Cancer Institutes (NCI) Clinical Proteomic Tumor Analysis Consortium (CPTAC) investigated the effect of cold ischemia on the proteome of fresh frozen tumors.

  11. A Research on the Extracurricular English Learning a-mong Non-English Majors%非英语专业本科生英语课外学习现状调查

    Institute of Scientific and Technical Information of China (English)

    许润江; 左文静


    本文采用问卷和访谈的形式,在非英语专业本科学生中开展有关英语课外学习情况的调查研究。调查研究从有关英语课外学习的认知、所用时间、学习内容、学习评价等四方面进行,表明学生对于英语课外学习的认识有些偏差,英语学习大多花费在应对考试上,学习缺乏有效的评价。因此,学生的英语课外学习亟须加强。%This paper develops a research on the extracurricular English learning among university students through questionnaire and interview. The research explores from the idea, time, content and assessment of extracurricular English learning. It shows that students have inappropriate idea on extracurricular English learning and they learn English exam-oriented. Effective assess-ment is not arranged in extracurricular English learning. Thus, extracurricular English learning should be strengthened.

  12. Systems biology in the frontier of cancer research:a report of the Second International Workshop of Cancer Systems Biology

    Institute of Scientific and Technical Information of China (English)

    Juan Cui; Yan-Chun Liang; Ying Xu


    The report summarizes the Second International Workshop of Cancer Systems Biology held on July 5-6,2012 in Changchun,China.The goal of the workshop was to bring together cancer researchers with different backgrounds to share their views about cancer and their experiences in fighting against cancer,and to gain new and systems-level understanding about cancer formation,progression,diagnosis,and treatment through exchanging ideas.

  13. Non-native scientists, research dissemination and English neologisms: What happens in the early stages of reception and re-production?

    Directory of Open Access Journals (Sweden)

    Daniel Linder


    Full Text Available That the English language is the prevailing language in international scientific discourse is an undeniable fact for research professionals who are non-native speakers of English (NNSE. An exploratory, survey-based study of scientists in the experimental disciplines of neuroscience and medicine seeks to reveal, on the one hand, the habits of scientists who in their research practice come across neologisms in English and need to use them in oral and written scientific discourse in their own languages, and, on the other hand, their attitudes towards these neologisms and towards English as the language of international science. We found that all scientists write and publish their research articles (RAs in English and most submit them unrevised by native speakers of English. When first encountering a neologism in English, scientists tend to pay close attention to these new concepts, ideas or terms and very early in the reception process attempt to coin acceptable, natural-sounding Spanish equivalents for use in the laboratory and in their Spanish texts. In conjunction with the naturalized Spanish term, they often use the English neologism verbatim in a coexistent bilingual form, but they avoid using only the English term and very literal translations. These behaviors show an ambivalent attitude towards English (the language of both new knowledge reception and dissemination of their RAs and Spanish (used for local professional purposes and for popularization: while accepting to write in their acquired non-native language, they simultaneously recognize that their native language needs to preserve its specificity as a language of science.

  14. Language and Identity in the English Version of Italian University Webistes: Preliminary Research Results

    Directory of Open Access Journals (Sweden)

    Laura Ferrarotti


    Full Text Available This study presents the preliminary results of a corpus-based research concerning the promotional language of the English version of some Italian university websites. One of the assumptions of this work is that, as many scholars have pointed out, the role of institutional and educational websites today goes well beyond the strict objective of providing information. In fact, universities in particular have clearly adopted promotional strategies to attract students. The present analysis deals with the introductory sections of 14 university websites which vary in their headings, length and focus. These introductory sections are typically entitled “About us”, “The University of…”, “The History of the University of...”, “Our History”, or that may even present a “Welcome” message by the Rector. They intend to reach out, in particular, to foreign students, and as such contribute to the construction of the university’s identity. Data are being subdivided on the basis of region: North, Center, South of Italy and the islands of Sardinia and Sicily, and are analyzed on the basis of a quantitative and qualitative approach. Through a comparison of different universities’ introductory sections, it was possible to detect noteworthy differences. For instance, while for some universities the information is rather concise as it mainly presents figures and descriptions, others present long historical accounts of the institution, and even mention well-known alumni characters who studied there. What emerges is a lack of uniformity that reveals the fact that these university websites are a genre in transition caught, so to say, between a traditional approach of providing information and a clearly promotional one in constructing their own identity.

  15. Targeting hedgehog signaling in cancer: research and clinical developments

    Directory of Open Access Journals (Sweden)

    Xie J


    Full Text Available Jingwu Xie, Christopher M Bartels, Scott W Barton, Dongsheng GuWells Center for Pediatric Research, Division of Hematology and Oncology, Department of Pediatrics, Indiana University Simon Cancer Center, Indiana University, Indianapolis, IN, USAAbstract: Since its first description in Drosophila by Drs Nusslein-Volhard and Wieschaus in 1980, hedgehog (Hh signaling has been implicated in regulation of cell differentiation, proliferation, tissue polarity, stem cell maintenance, and carcinogenesis. The first link of Hh signaling to cancer was established through studies of Gorlin syndrome in 1996 by two independent teams. Later, it was shown that Hh signaling may be involved in many types of cancer, including skin, leukemia, lung, brain, and gastrointestinal cancers. In early 2012, the US Food and Drug Administration approved the clinical use of Hh inhibitor Erivedge/vismodegib for treatment of locally advanced and metastatic basal cell carcinomas. With further investigation, it is possible to see more clinical applications of Hh signaling inhibitors. In this review, we will summarize major advances in the last 3 years in our understanding of Hh signaling activation in human cancer, and recent developments in preclinical and clinical studies using Hh signaling inhibitors.Keywords: hedgehog, smoothened, PTCH1, cancer, signal transduction, clinical trials, animal model

  16. Application of English Euphemisms in English Teaching

    Institute of Scientific and Technical Information of China (English)

    ZENG Si-si


    With the rapid development of the society, people are expected to improve their language quality as well. So when people have to express something unpleasant, they prefer to employ some mild, implicit and euphemistic expressions. Meanwhile, an increasing number of scientists indulge themselves in studying English euphemisms from different perspectives, such as linguis⁃tics, pragmatics, and psychology and so on. English Euphemisms applied in class can not only help create a relaxing and lively at⁃mosphere but also protect the students’self-esteem and stimulate their interests in English. However, the researches on the ef⁃fects of applying English euphemisms in English class are few. Therefore, Based on Face-saving Theory, this paper intends to highlight the importance of applying English euphemisms in English teaching.

  17. 76 FR 66728 - Government-Owned Inventions; Licensing and Collaborative Research Opportunity for PANVAC-Cancer... (United States)


    ... the Laboratory of Tumor Immunology and Biology, Center for Cancer Research, NCI. The CRADA partner... Research Opportunity for PANVAC--Cancer Vaccine for the Prevention and Treatment of Colorectal Cancer... Technology Transfer Center, National Cancer Institute, 6120 Executive Boulevard, Suite 450, Rockville,...

  18. Leveraging the power of pooled data for cancer outcomes research

    Institute of Scientific and Technical Information of China (English)

    Kiara Hugh-Yeun; Winson Y. Cheung


    Background: Clinical trials continue to be the gold standard for determining the effcacy of novel cancer treatments, but they may also expose participants to the potential risks of unpredictable or severe toxicities. The development of validated tools that better inform patients of the beneifts and risks associated with clinical trial participation can facilitate the informed consent process. The design and validation of such instruments are strengthened when we leverage the power of pooled data analysis for cancer outcomes research. Main body: In a recent study published in the Journal of Clinical Oncology entitled“Determinants of early mortal‑ity among 37,568 patients with colon cancer who participated in 25 clinical trials from the adjuvant colon cancer endpoints database,”using a large pooled analysis of over 30,000 study participants who were enrolled in clinical trials of adjuvant therapy for early‑stage colon cancer, we developed and validated a nomogram depicting the predictors of early cancer mortality. This database of pooled individual‑level data allowed for a comprehensive analysis of poor prognostic factors associated with early death;furthermore, it enabled the creation of a nomogram that was able to reliably capture and quantify the beneift‑to‑risk proifle for patients who are considering clinical trial participation. This tool can facilitate treatment decision‑making discussions. Conclusion: As China and other Asian countries continue to conduct oncology clinical trials, efforts to collate patient‑level information from these studies into a large data repository should be strongly considered since pooled data can increase future capacity for cancer outcomes research, which, in turn, can enhance patient‑physician discus‑sions and optimize clinical care.

  19. Cancer research and therapy: Where are we today?

    Directory of Open Access Journals (Sweden)

    Sampada Sawant


    Full Text Available Till date scientists are struggling to understand the complete mechanism of carcinogenesis. In future, the real time detection of cancer may help scientists to identify some of the complicated biological mechanisms. Certain special features of cancer cells enable researchers to deliver the drug or to develop the right drug therapy. These cell properties include over expression or over activity in uptake of certain nutrients e.g. folic acid and increased permeability. Listed properties might vary depending upon the type of cancer and can be fully exploited by using nanoparticles either to detect the site of cancer or to direct the drug at the affected site. Product approach like drug conjugates, complexes serves as a good platform to solve issues like solubility, toxicity, poor penetration and stability related to cancer drugs. Beside this, several drug delivery platforms are under development by researchers in academia as well as in industry to deliver therapeutic molecules and new chemical entities to the targeted site in body. Amongst them, nanotechnology both at molecular and supramolecular level is a leading platform and can help to image, detect and treat cancer. Surface modification of nanoparticles by coating or anchoring their surface with special markers, materials, peptide, proteins, antibodies or antigens add extra feature and thereby can enhance the effectiveness. These treatments can be used individually or in combined form. In this review, advances on nanotechnological platform are discussed together with some assisting techniques like magnetic field, photo or light field, sonic rays are touched upon. New biological therapies that are advancing in this direction include the antisense therapy, cell therapy, gene therapy, radiation therapy and SiRNA interfaces which are discussed in brief in this article. This article gives short overview on use of complementary and alternative medicine for treatment of cancer such as traditional

  20. Community-based participatory research: its role in future cancer research and public health practice. (United States)

    Simonds, Vanessa W; Wallerstein, Nina; Duran, Bonnie; Villegas, Malia


    The call for community-based participatory research approaches to address cancer health disparities is increasing as concern grows for the limited effectiveness of existing public health practice and research in communities that experience a disparate burden of disease. A national study of participatory research projects, Research for Improved Health, funded by the National Institutes of Health (2009-2013), identified 64 of 333 projects focused on cancer and demonstrated the potential impact participatory approaches can have in reducing cancer disparities. Several projects highlight the success of participatory approaches to cancer prevention and intervention in addressing many of the challenges of traditional practice and research. Best practices include adapting interventions within local contexts, alleviating mistrust, supporting integration of local cultural knowledge, and training investigators from communities that experience cancer disparities. The national study has implications for expanding our understanding of the impact of participatory approaches on alleviating health disparities and aims to enhance our understanding of the barriers and facilitators to effective community-based participatory research.

  1. Collaboration - Office of Cancer Clinical Proteomics Research (United States)

    Despite great strides in proteomics and the growing number of articles citing the discovery of potential biomarkers, the actual rate of introduction of Food and Drug Administration (FDA) approved protein analytes has been relatively unchanged over the past 10 years. One of reasons for the lack of new protein-based biomarkers approved has been a lack of information and understanding by the proteomics research community to the regulatory process used by the FDA.

  2. Effect on English Output Competence by Exerting Lexical Chunks Ap-proach in Autonomous Learning Model Research

    Institute of Scientific and Technical Information of China (English)

    梅王星; 王艳荣


    English language skill is an important part of the comprehensive linguistic competence for college students. Especially the language output competence by students Autonomous Learning. During the 70s of the last century, Becker came up with the term and and later put forward his Lexical Chunks. Since then, it has been researched increasingly and paid more and more atten⁃tion to due to the fact that lexical chunks possess the features of both vocabulary and grammar. Teachers should exert lexical chunks approach, consciously raise students’awareness of lexical chunks, and design various instructional activities based on dif⁃ferent teaching contents to improve students’language output competence. In this paper, the author carries out an experiment on the college students from two classes of the same level in Grade one. And compared with the experimental class itself or with the control class, found the students in experimental class have made far greater progress in English speaking and writing.

  3. CPTAC Scientific Symposium - Office of Cancer Clinical Proteomics Research (United States)

    On behalf of the National Cancer Institute and the Office of Cancer Clinical Proteomics Research, you are invited to the First Annual CPTAC Scientific Symposium on Wednesday, November 13, 2013. The purpose of this symposium, which consists of plenary and poster sessions, is for investigators from CPTAC community and beyond to share and discuss novel biological discoveries, analytical methods, and translational approaches using CPTAC data. All scientists who use, or wish to use CPTAC data are welcome to participate at this free event. The symposium will be held at the Natcher Conference Facility on the main campus of the National Institutes of Health in Bethesda, Maryland.

  4. The value of research collaborations and consortia in rare cancers. (United States)

    Blay, Jean-Yves; Coindre, Jean-Michel; Ducimetière, Françoise; Ray-Coquard, Isabelle


    Rare cancers are defined by an incidence of less than six per 100,000 people per year. They represent roughly 20% of all human cancers and are associated with worse survival than are so-called frequent tumours, because of delays to accurate diagnosis, inadequate treatments, and fewer opportunities to participate in clinical trials (because of a paucity of dedicated trials from both academic and industrial sponsors). In this Series paper, we discuss how these challenges can be addressed by research consortia and suggest the integration of these consortia with reference networks, which gather multidisciplinary expert centres, for management of rare tumours.

  5. Clinical cancer research: the past, present and the future. (United States)

    DeVita, Vincent T; Eggermont, Alexander M M; Hellman, Samuel; Kerr, David J


    In the past decade, we have witnessed unprecedented changes and some remarkable advances that have enabled true personalized medicine. Nevertheless, many challenges in clinical cancer research remain and need to be overcome if we are to witness similar progress in the next decade. Such hurdles include, but are not limited to, clinical development and testing of multiple agents in combination, design of clinical trials to best accommodate the ever increasing knowledge of heterogeneity of the disease, regulatory challenges relating to drug development and trial design, and funding for basic research. With this in mind, we asked four leading cancer researchers from around the world, and who have been associated with the journal since its launch in November 2004 what, in their opinion, we have learnt over the past 10 years and how we should progress in the next 10 years.

  6. Why is it crucial to reintegrate pathology into cancer research? (United States)

    Rodriguez-Canales, Jaime; Eberle, Franziska C; Jaffe, Elaine S; Emmert-Buck, Michael R


    The integration of pathology with molecular biology is vital if we are to enhance the translational value of cancer research. Pathology represents a bridge between medicine and basic biology, it remains the gold standard for cancer diagnosis, and it plays an important role in discovery studies. In the past, pathology and cancer research were closely associated; however, the molecular biology revolution has shifted the focus of investigators toward the molecular alterations of tumors. The reductionist approach taken in molecular studies is producing great insight into the inner workings of neoplasia, but it can also minimize the importance of histopathology and of understanding the disease as a whole. In turn, pathologists can underestimate the role of molecular studies in developing new ancillary techniques for clinical diagnosis. A multidisciplinary approach that integrates pathology and molecular biology within a translational research system is needed. This process will require overcoming cultural barriers and can be achieved through education, a more effective incorporation of pathology into biological research, and conversely an integration of biological research into the pathology laboratory.

  7. Research on pragmatic failure in Business English based on cultural awareness

    Directory of Open Access Journals (Sweden)

    Xu Yangye


    Full Text Available Business English is an important part of business negotiation. From the perspective of cultural differences in various countries, the pragmatic failure in the negotiation process is inevitable. This paper introduces the manifestation pattern of pragmatic failure in English, and establishes a hierarchical structure by the use of AHP, of which the target layer is the most prone areas of pragmatic failure; the criteria layer is the fuzzy words, people’s names, tense and mood; the scheme layer is the food culture, traditional culture and etiquette culture, and also evaluates the most prone areas of pragmatic failure in these three aspects. The results show that, the probability of pragmatic failure for the food culture in Business English is the highest, followed by the etiquette culture. Under the premise of combination with the actual situation, this paper analyzes the rationality of the model.

  8. Perceptions of patient-provider communication in breast and cervical cancer-related care: a qualitative study of low-income English- and Spanish-speaking women. (United States)

    Simon, Melissa A; Ragas, Daiva M; Nonzee, Narissa J; Phisuthikul, Ava M; Luu, Thanh Ha; Dong, XinQi


    To explore patient perceptions of patient-provider communication in breast and cervical cancer-related care among low-income English- and Spanish-speaking women, we examined communication barriers and facilitators reported by patients receiving care at safety net clinics. Participants were interviewed in English or Spanish after receiving an abnormal breast or cervical cancer screening test or cancer diagnosis. Following an inductive approach, interviews were coded and analyzed by the language spoken with providers and patient-provider language concordance status. Of 78 participants, 53 % (n = 41) were English-speakers and 47 % (n = 37) were Spanish-speakers. All English-speakers were language-concordant with providers. Of Spanish-speakers, 27 % (n = 10) were Spanish-concordant; 38 % (n = 14) were Spanish-discordant, requiring an interpreter; and 35 % (n = 13) were Spanish mixed-concordant, experiencing both types of communication throughout the care continuum. English-speakers focused on communication barriers, and difficulty understanding jargon arose as a theme. Spanish-speakers emphasized communication facilitators related to Spanish language use. Themes among all Spanish-speaking sub-groups included appreciation for language support resources and preference for Spanish-speaking providers. Mixed-concordant participants accounted for the majority of Spanish-speakers who reported communication barriers. Our data suggest that, although perception of patient-provider communication may depend on the language spoken throughout the care continuum, jargon is lost when health information is communicated in Spanish. Further, the respective consistency of language concordance or interpretation may play a role in patient perception of patient-provider communication.

  9. ENRICH Forum: Ethical aNd Regulatory Issues in Cancer ResearcH (United States)

    ENRICH Forum: Ethical aNd Regulatory Issues in Cancer ResearcH, designed to stimulate dialogue on ethical and regulatory issues in cancer research and promote awareness of developing policies and best practices.

  10. 英语学习及教学研究%English Learning and Its Teaching Research

    Institute of Scientific and Technical Information of China (English)



    The paper analyzes the difficulties students' face while learning English. It also explains the reasons and the ways to solve these problems,emphasizing the English learning skills in listening,speaking,reading and writing.%本文从教学实际角度出发,深刻剖析了学生在学习英语过程中所遇到的困难及原因及其解决方法,重点论述了听、说、读、写四项基本技能在英语学习中的运用技巧。

  11. A Research of Logical Connectors Used by Chinese English Learners from the Longitudinal Perspective

    Institute of Scientific and Technical Information of China (English)



    Based on Corpus, the present study investigates the developmental features of the use of logical connectors. Chinese learners use all kinds of logical connectors in their English writing, but their frequencies are different. Chinese learners, especially high school students rely heavily on a few logical connectors, the used of adverbials lack diversity. As students learn English more, the use of adverbials present different developmental features. In, addition, there is a significant difference between ST2 and ST3 in the use of logical connectors, but there is no significant difference between ST3 and ST4.

  12. 高职院校非英语专业英语学习动机与职业需求相关性研究%English Learning Motives of Non-English Major Students and Career Requirements Relevance Research

    Institute of Scientific and Technical Information of China (English)



    高职院校非英语专业学生的英语基础偏低,一直是英语教学中英语成绩提高的瓶颈,这体现了学生对英语学习的动机不明确。通过调查发现,学生在未来职业中对英语的需求是提高高职高专英语教学水平的关键因素。以此为契机,展开高职院校非英语专业英语学习动机与职业需求相关性的研究,并对今后的教学提出改革方向与授课策略。%Poor English of non-English major students in vocational colleges always infl uences the improvement of their English marks, which actually indicates they are unclear of English learning motives. This article researches deeply on the relationship between the motivation of English learning and the requirements of future career. Furthermore it also illustrates several strategies in English-teaching reform on the basis of the close relationship between learning motives and career requirements.

  13. Proteomics in epigenetics: new perspectives for cancer research. (United States)

    Bartke, Till; Borgel, Julie; DiMaggio, Peter A


    The involvement of epigenetic processes in the origin and progression of cancer is now widely appreciated. Consequently, targeting the enzymatic machinery that controls the epigenetic regulation of the genome has emerged as an attractive new strategy for therapeutic intervention. The development of epigenetic drugs requires a detailed knowledge of the processes that govern chromatin regulation. Over the recent years, mass spectrometry (MS) has become an indispensable tool in epigenetics research. In this review, we will give an overview of the applications of MS-based proteomics in studying various aspects of chromatin biology. We will focus on the use of MS in the discovery and mapping of histone modifications and how novel proteomic approaches are being utilized to identify and study chromatin-associated proteins and multi-subunit complexes. Finally, we will discuss the application of proteomic methods in the diagnosis and prognosis of cancer based on epigenetic biomarkers and comment on their future impact on cancer epigenetics.

  14. Effective Practices for Developing Literacy Skills of English Language Learners in the English Language. Research Report. ETS RR-12-03 (United States)

    Turkan, Sultan; Bicknell, Jerome; Croft, Andrew


    This paper is a review of literature presenting instructional strategies--based on normative as well as empirical arguments--which have proven to be effective in envisioning what "all" teachers need to know and be able to do to teach English language arts (ELA) to English language learners (ELLs). The studies selected for review address…

  15. Funding Opportunities Available for Innovative SBIR Development - Office of Cancer Clinical Proteomics Research (United States)

    Does your small business need early-stage financing to take its cancer research to the next level? The National Cancer Institute Small Business Innovation Research (NCI SBIR) Development Center has released $5 million for new contract funding opportunities to support cancer research and technology development in key emerging areas of need.

  16. Research on Teaching Strategies of College English Micro-lecture%英语微课教学策略研究

    Institute of Scientific and Technical Information of China (English)



    通过教学选题聚焦、教学设计切片、翻转课堂、微视频录制和测试等,从英语语法点、读写策略、翻译技巧与听口表达等英语教学的特点入手,并以3种教学设计的切片为扩展,深入探讨了大学英语微课的教学策略,为提升大学英语微课教学的质量和水平提供具有实践意义的参考。%Through focusing on choice of teaching topic , course design slice , flipped classroom , micro—video recording and tests ,the article starts with analyzing the feature of English grammar points ,reading and writing strategies ,translation skills ,listening and oral performance ,etc .Combined with three slices of teaching design ,this article makes a further research on teaching strategies in college English micro—lecture ,which provides practical references for improving the quality and level of the college English micro-lecture education .

  17. Language through literature through language: An action research report on the English 100 course at the University of North West

    Directory of Open Access Journals (Sweden)

    I. Butler


    Full Text Available In this article the writer surveys attitudes to the integration of language and literature in ESL/EFL teaching, noting the reservations that have been expressed about it in the past, and which still continue to linger in some quarters. Against this background he then describes the development and implementation of an integrated English syllabus at the University of North West, focusing on his current action research in teaching the first year modules. Using examples from the material he has developed for these modules, he demonstrates how the principles of language/literature integration, as articulated by writers in the field, can be translated into practice in a number of ways. Since this is an on-going project the writer presents his findings as a report on work in progress. The article does, however, conclude with a brief summary of the positive responses received from lecturers and students in response to questionnaires and surveys conducted in 2000 and 2001. A linguist deaf to the poetic function of language and a literary scholar indifferent to linguistic problems and unconversant with linguistic methods, are equally flagrant anachronisms. Roman Jakobson (in Simpson, 1997:ii I imagined how it would be like to study literature alone. This would be tough especially if English is not your first language. Just tough. (From the journal of an English 100 student, University of North West

  18. TOEFL11: A Corpus of Non-Native English. Research Report. ETS RR-13-24 (United States)

    Blanchard, Daniel; Tetreault, Joel; Higgins, Derrick; Cahill, Aoife; Chodorow, Martin


    This report presents work on the development of a new corpus of non-native English writing. It will be useful for the task of native language identification, as well as grammatical error detection and correction, and automatic essay scoring. In this report, the corpus is described in detail.

  19. Educating English Language Learners: Instructional Approaches and Teacher Collaboration in Philadelphia Public Schools. PERC Research Brief (United States)

    Reumann-Moore, Rebecca; Rowland, Jeannette; Hughes, Rosemary; Lin, Joshua


    Districts, charter management organizations, and individual schools can learn a great deal from each other about strategies for creating robust and supportive learning environments for English Language Learners (ELLS). This brief highlights key findings about how Philadelphia public schools were crafting instructional approaches to serve their…

  20. Una ricerca sul bilinguismo precoce italo-inglese (Research on Early Italian-English Bilingualism). (United States)

    Taeschner, Traute; And Others


    The purpose of this study was to attempt to verify the theory of Taeschner and Volterra (1976) that bilingual children pass through three distinct phases while becoming perfectly bilingual. The 12 subjects were English-Italian bilingual children between the ages of 1.6 and 4.6. (CFM)

  1. Challenges in Evaluating Special Education Teachers and English Language Learner Specialists. Research & Policy Brief (United States)

    Holdheide, Lynn R.; Goe, Laura; Croft, Andrew; Reschly, Daniel J.


    Current emphasis on teacher effectiveness in educational policy poses a challenge for the evaluation of special education teachers and English language learner (ELL) specialists. Most evaluation systems focus on student achievement and teacher practice; however, few systems have the capacity to differentiate among specialty area educators, address…

  2. Research on the Education System of Business English Courses Based on the Case of GDUFS (United States)

    Zhengguo, Zhu; Lili, Lin; Wenzhong, Zhu


    In order to develop a more scientific education system of Business English courses, this paper studies the case of Guangdong University of Foreign Studies (GDUFS, one of Chinese top-three foreign language universities) by questionnaires. The result shows that: 1) Most of the students hope that the school could add more business courses in the…

  3. Researching the Effects of Teaching Grammar Rules to English Second Language Adult Learners (United States)

    Ayliff, D.


    This article describes the effects of an interventionist form-focused course on the written English of first-year second language university learners. For two semester courses the form (or grammar) of the language was concentrated upon. During the first semester the use of correct grammar was focussed on intensively, while during the second…

  4. Research on College English Listening Teaching Based on Cross-cultural Communication

    Institute of Scientific and Technical Information of China (English)

    刘娇; 常世财


    This paper clarified the importance of improving cross-cultural communicative competence in listening teaching from the perspective of the relationship between cross-cultural communicative competence and listening teaching.For the hearing ob-stacles caused by cultural differences,the author presented that cross-cultural awareness should be permeated in the classroom to improve students'English listening skills.

  5. The Effectiveness of Reading Interventions for English Learners: A Research Synthesis (United States)

    Richards-Tutor, Catherine; Baker, Doris L.; Gersten, Russell; Baker, Scott K.; Smith, Jeanie Mercier


    This article reviews published experimental studies from 2000 to 2012 that evaluated the effects of providing reading interventions to English learners who were at risk for experiencing academic difficulties, including students with learning disabilities. Criteria included: (a) the study was published in a peer-referred journal, (b) the study was…

  6. Assessment and Intervention for English Language Learners with Primary Language Impairment: Research-Based Best Practices (United States)

    Pieretti, Robert A.; Roseberry-McKibbin, Celeste


    Speech-language pathologists (SLPs) are experiencing the exciting challenge of serving increasing numbers of English Language Learners (ELLs) in U.S. schools. When ELLs struggle in school, they may be overreferred for speech-language services. SLPs are routinely expected to differentiate a language difference based on cultural, linguistic, and…

  7. Focus Group Research on the Implications of Adopting the Unified English Braille Code (United States)

    Wetzel, Robin; Knowlton, Marie


    Five focus groups explored concerns about adopting the Unified English Braille Code. The consensus was that while the proposed changes to the literary braille code would be minor, those to the mathematics braille code would be much more extensive. The participants emphasized that "any code that reduces the number of individuals who can access…

  8. Harnessing Storytelling as a Sociopragmatic Skill: Applying Narrative Research to Workplace English Courses (United States)

    Holmes, Janet; Marra, Meredith


    Narratives are often overlooked in workplace talk, but they contribute in crucial ways to relationship building and identity construction in workplace interaction. In this article we analyse narratives told by skilled migrants from non-English-speaking backgrounds during a workplace internship conducted as part of a Workplace Communication course.…

  9. Tissue-engineered models of human tumors for cancer research (United States)

    Villasante, Aranzazu; Vunjak-Novakovic, Gordana


    Introduction Drug toxicity often goes undetected until clinical trials, which are the most costly and dangerous phase of drug development. Both the cultures of human cells and animal studies have limitations that cannot be overcome by incremental improvements in drug-testing protocols. A new generation of bioengineered tumors is now emerging in response to these limitations, with potential to transform drug screening by providing predictive models of tumors within their tissue context, for studies of drug safety and efficacy. An area that could greatly benefit from these models is cancer research. Areas covered In this review, the authors first describe the engineered tumor systems, using Ewing's sarcoma as an example of human tumor that cannot be predictably studied in cell culture and animal models. Then, they discuss the importance of the tissue context for cancer progression and outline the biomimetic principles for engineering human tumors. Finally, they discuss the utility of bioengineered tumor models for cancer research and address the challenges in modeling human tumors for use in drug discovery and testing. Expert opinion While tissue models are just emerging as a new tool for cancer drug discovery, they are already demonstrating potential for recapitulating, in vitro, the native behavior of human tumors. Still, numerous challenges need to be addressed before we can have platforms with a predictive power appropriate for the pharmaceutical industry. Some of the key needs include the incorporation of the vascular compartment, immune system components, and mechanical signals that regulate tumor development and function. PMID:25662589

  10. Predicting health literacy among English-as-a-second-Language older Chinese immigrant women to Canada: comprehension of colon cancer prevention information. (United States)

    Todd, Laura; Hoffman-Goetz, Laurie


    Inadequate health literacy has been identified as a barrier to the utilization of health-care services, including cancer screening. This study examined predictors of health literacy among 106 older Chinese immigrant women to Canada and how colon cancer information presented in their first versus second language affected health literacy skill. Only 38.7% of the women had adequate health literacy based on Short Test of Functional Health Literacy for Adults, and 54.3% had adequate comprehension of the colon cancer information. Comprehension of the cancer information was significantly lower among women who received the information in English compared with those who received the information in Chinese. Age, acculturation, self-reported proficiency reading English, and education were significant predictors of health literacy but varied depending on the measure of health literacy used and language of the information. Presentation of cancer prevention information in one's first rather than second language improves health literacy but does not eliminate comprehension difficulties for older ESL Chinese immigrants.

  11. Cancer Treatment-Related Cardiotoxicity: Understanding the Current State of Knowledge and Developing Future Research Priorities (United States)

    Cancer Treatment-Related Cardiotoxicity: Understanding the Current State of Knowledge and Developing Future Research Priorities, a 2013 workshop sponsored by the Epidemiology and Genomics Research Program.

  12. Cancer genomics object model: an object model for multiple functional genomics data for cancer research. (United States)

    Park, Yu Rang; Lee, Hye Won; Cho, Sung Bum; Kim, Ju Han


    The development of functional genomics including transcriptomics, proteomics and metabolomics allow us to monitor a large number of key cellular pathways simultaneously. Several technology-specific data models have been introduced for the representation of functional genomics experimental data, including the MicroArray Gene Expression-Object Model (MAGE-OM), the Proteomics Experiment Data Repository (PEDRo), and the Tissue MicroArray-Object Model (TMA-OM). Despite the increasing number of cancer studies using multiple functional genomics technologies, there is still no integrated data model for multiple functional genomics experimental and clinical data. We propose an object-oriented data model for cancer genomics research, Cancer Genomics Object Model (CaGe-OM). We reference four data models: Functional Genomic-Object Model, MAGE-OM, TMAOM and PEDRo. The clinical and histopathological information models are created by analyzing cancer management workflow and referencing the College of American Pathology Cancer Protocols and National Cancer Institute Common Data Elements. The CaGe-OM provides a comprehensive data model for integrated storage and analysis of clinical and multiple functional genomics data.

  13. Overcoming the challenges to consumer involvement in cancer research


    Stevens, Tony; Wilde, David; Hunt, John; Ahmedzai, Sam H


    Introduction  Within the last decade, there have been many government initiatives to promote consumer involvement in research, especially in cancer. At the same time, the number and influence of consumer groups themselves have expanded. However, the organizational infrastructure necessary to facilitate consumer involvement has not been developed. Consequently, consumer involvement has tended to remain essentially localized and project driven, with no strategic or regional lead.

  14. Economic terms and beyond how researchers in specialised varieties of English can benefit from focusing on terms

    CERN Document Server

    Resche, Catherine


    This book, which is aimed at researchers in specialised varieties of English, provides an illustration of how linguists can use terms, i.e. the expression of concepts in specialised fields, as entry points to explore any specialised domain, whether academic or professional, and to get acquainted with its history, its culture, and the evolution of the ideas that have nurtured it. Choosing the field of economics as an example, the author approaches terms from a diachronic, descriptive and contextual perspective, focusing on neonyms, metaphorical, ambiguous or indeterminate terms, as well as inte

  15. Cancer (United States)

    ... cancer Non-Hodgkin lymphoma Ovarian cancer Pancreatic cancer Testicular cancer Thyroid cancer Uterine cancer Symptoms Symptoms of cancer ... tumor Obesity Pancreatic cancer Prostate cancer Stomach cancer Testicular cancer Throat or larynx cancer Thyroid cancer Patient Instructions ...

  16. Consumer input into research: the Australian Cancer Trials website

    Directory of Open Access Journals (Sweden)

    Butow Phyllis N


    Full Text Available Abstract Background The Australian Cancer Trials website (ACTO was publicly launched in 2010 to help people search for cancer clinical trials recruiting in Australia, provide information about clinical trials and assist with doctor-patient communication about trials. We describe consumer involvement in the design and development of ACTO and report our preliminary patient evaluation of the website. Methods Consumers, led by Cancer Voices NSW, provided the impetus to develop the website. Consumer representative groups were consulted by the research team during the design and development of ACTO which combines a search engine, trial details, general information about trial participation and question prompt lists. Website use was analysed. A patient evaluation questionnaire was completed at one hospital, one week after exposure to the website. Results ACTO's main features and content reflect consumer input. In February 2011, it covered 1, 042 cancer trials. Since ACTO's public launch in November 2010, until the end of February 2011, the website has had 2, 549 new visits and generated 17, 833 page views. In a sub-study of 47 patient users, 89% found the website helpful for learning about clinical trials and all respondents thought patients should have access to ACTO. Conclusions The development of ACTO is an example of consumers working with doctors, researchers and policy makers to improve the information available to people whose lives are affected by cancer and to help them participate in their treatment decisions, including consideration of clinical trial enrolment. Consumer input has ensured that the website is informative, targets consumer priorities and is user-friendly. ACTO serves as a model for other health conditions.

  17. Collaborating to Move Research Forward: Proceedings of the 10th Annual Bladder Cancer Think Tank. (United States)

    Kamat, Ashish M; Agarwal, Piyush; Bivalacqua, Trinity; Chisolm, Stephanie; Daneshmand, Sia; Doroshow, James H; Efstathiou, Jason A; Galsky, Matthew; Iyer, Gopa; Kassouf, Wassim; Shah, Jay; Taylor, John; Williams, Stephen B; Quale, Diane Zipursky; Rosenberg, Jonathan E


    The 10th Annual Bladder Cancer Think Tank was hosted by the Bladder Cancer Advocacy Network and brought together a multidisciplinary group of clinicians, researchers, representatives and Industry to advance bladder cancer research efforts. Think Tank expert panels, group discussions, and networking opportunities helped generate ideas and strengthen collaborations between researchers and physicians across disciplines and between institutions. Interactive panel discussions addressed a variety of timely issues: 1) data sharing, privacy and social media; 2) improving patient navigation through therapy; 3) promising developments in immunotherapy; 4) and moving bladder cancer research from bench to bedside. Lastly, early career researchers presented their bladder cancer studies and had opportunities to network with leading experts.

  18. Why do some countries publish more than others? An international comparison of research funding, English proficiency and publication output in highly ranked general medical journals. (United States)

    Man, Jonathan P; Weinkauf, Justin G; Tsang, Monica; Sin, Don D


    National factor(s) influencing publication output in the highest ranked medical journals are largely unknown. We sought to examine the relationship between national research funding and English proficiency on publication output. We identified all original research articles appearing in the five highest ranked general medical journals between 1997 and 2001. Using the country of the corresponding author as the source nation for each article, we determined a standardized publication rate across developed nations. We used multiple regression techniques to determine the influence of national expenditures on research and scores from the Test of English as a Foreign Language (TOEFL), a surrogate for English proficiency, on publication output. There was a significant relationship of national spending on research and TOEFL scores to publication output of developed countries (p = 0.04; p < 0.01, respectively). These two variables explained approximately 71.5% of the variation in publication rate across developed nations around the world (R = 0.85; p < 0.01). Normalized for population size, English-speaking nations and certain northern European countries such as Denmark, The Netherlands, Switzerland, and Sweden had the highest rate of publication in the five highest ranked general medical journals, while Asian countries had generally low rates of publication. Research spending and English proficiency were strongly associated with publication output in the highest ranked general medical journals. While these data cannot be considered definitive due to their observational nature, they do suggest that for English-language medical journals, research funding and English proficiency may be important determinants of publication.

  19. Active Barrett's Esophagus Translational Research Network Grants | Division of Cancer Prevention (United States)

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  20. Supportive and Palliative Care Research Clinical Trials | Division of Cancer Prevention (United States)

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  1. Supportive and Palliative Care Research Funding Opportunities | Division of Cancer Prevention (United States)

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  2. College English Students’Autonomous Learning Motivation and Cultivation Model Research

    Institute of Scientific and Technical Information of China (English)

    王艳荣; 李娥


    Studying the autonomous learning motivation and excitation model can stimulate intrinsic motivation of foreign language learners,develop students self-management strategy evaluation are very necessary.The purpose of this paper is to give students the skills of listening and speaking for their autonomous learning.Then study the cultivation and motivation of college English students autonomous learning,hoping to make students to learn autonomous learning and stimulate their motivation fully.

  3. A Research on Errors in Paraphrasing in Academic Writing of English Majors

    Institute of Scientific and Technical Information of China (English)



    This paper seeks to identify errors made my English majors in academic writing so that preventive measures such as effective pedagogic strategies and learning activities can be devised and conducted to reduce these errors. In order to facilitate learners in horning their skills in paraphrasing, a practical strategy is proposed. It is hoped that by implementing strategies like this, ESL learners will be confident in using their own words to paraphrase academic texts with minimal errors.

  4. The Research of English Teachers’ Confusion and Professional Development Direction Under the New Situation

    Institute of Scientific and Technical Information of China (English)

    Liu; Haiying


    At present,because of the confusion of various factors such as enrollment expansion of colleges,the increasing graduates and so on,the teachers of higher colleges will not only finish the burdensome teaching task,but also finish their own promotion and development gradually to develop students’ practical abilities and value cultural education and personality.English teachers should pay more attention to their professional development.

  5. A Research of Task-based Language Teaching Applied to the College Oral English Teaching

    Institute of Scientific and Technical Information of China (English)

    王景琦; 祝菁


    Task-based Language Teaching has been greatly applied to college English teaching after the traditional “PPP”teaching approach. The key links in TBLT are assignment, development and inspection of tasks. With the main method, interactive communication,“students-centered ” is stressed, and students' subjective dynamics is fully exerted. Class time can be effectively used and students' communicative ability is cultivated with the improvement of oral expression ability.

  6. The Research of English Teachers' Confusion and Professional Development Direction Under the New Situation

    Institute of Scientific and Technical Information of China (English)

    Liu Haiying


    At present,because of the confusion of various factors such as enrollment expansion of colleges,the increasing graduates and so on,the teachers of higher colleges will not only finish the burdensome teaching task,but also finish their own promotion and development gradually to develop students’ practical abilities and value cultural education and personality. English teachers should pay more attention to their professional development.

  7. Cancer Research Participation Beliefs and Behaviors of a Southern Black Population: A Quantitative Analysis of the Role of Structural Factors in Cancer Research Participation. (United States)

    Farr, Deeonna E; Brandt, Heather M; Comer, Kimberly D; Jackson, Dawnyéa D; Pandya, Kinjal; Friedman, Daniela B; Ureda, John R; Williams, Deloris G; Scott, Dolores B; Green, Wanda; Hébert, James R


    Increasing the participation of Blacks in cancer research is a vital component of a strategy to reduce racial inequities in cancer burden. Community-based participatory research (CBPR) is especially well-suited to advancing our knowledge of factors that influence research participation to ultimately address cancer-related health inequities. A paucity of literature focuses on the role of structural factors limiting participation in cancer research. As part of a larger CBPR project, we used survey data from a statewide cancer needs assessment of a Black faith community to examine the influence of structural factors on attitudes toward research and the contributions of both structural and attitudinal factors on whether individuals participate in research. Regression analyses and non-parametric statistics were conducted on data from 727 adult survey respondents. Structural factors, such as having health insurance coverage, experiencing discrimination during health care encounters, and locale, predicted belief in the benefits, but not the risks, of research participation. Positive attitudes toward research predicted intention to participate in cancer research. Significant differences in structural and attitudinal factors were found between cancer research participants and non-participants; however, directionality is confounded by the cross-sectional survey design and causality cannot be determined. This study points to complex interplay of structural and attitudinal factors on research participation as well as need for additional quantitative examinations of the various types of factors that influence research participation in Black communities.

  8. What's New in Stomach Cancer Research and Treatment? (United States)

    ... the body’s immune system fight the cancer. A Korean study showed that combining chemotherapy with an immunotherapy ... Cancer Atlas Press Room Cancer Statistics Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, ...

  9. Lower Breast Cancer Risk among Women following the World Cancer Research Fund and American Institute for Cancer Research Lifestyle Recommendations: EpiGEICAM Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Adela Castelló

    Full Text Available According to the "World Cancer Research Fund" and the "American Institute of Cancer Research" (WCRF/AICR one in four cancer cases could be prevented through a healthy diet, weight control and physical activity.To explore the association between the WCRF/AICR recommendations and risk of breast cancer.During the period 2006 to 2011 we recruited 973 incident cases of breast cancer and 973 controls from 17 Spanish Regions. We constructed a score based on 9 of the WCRF/AICR recommendations for cancer prevention:: 1Maintain adequate body weight; 2Be physically active; 3Limit the intake of high density foods; 4Eat mostly plant foods; 5Limit the intake of animal foods; 6Limit alcohol intake; 7Limit salt and salt preserved food intake; 8Meet nutritional needs through diet; S1Breastfeed infants exclusively up to 6 months. We explored its association with BC by menopausal status and by intrinsic tumor subtypes (ER+/PR+ & HER2-; HER2+; ER&PR-&HER2- using conditional and multinomial logistic models respectively.Our results point to a linear association between the degree of noncompliance and breast cancer risk. Taking women who met 6 or more recommendations as reference, those meeting less than 3 showed a three-fold excess risk (OR=2.98(CI95%:1.59-5.59, especially for postmenopausal women (OR=3.60(CI95%:1.24;10.47 and ER+/PR+&HER2- (OR=3.60(CI95%:1.84;7.05 and HER2+ (OR=4.23(CI95%:1.66;10.78 tumors. Noncompliance of recommendations regarding the consumption of foods and drinks that promote weight gain in premenopausal women (OR=2.24(CI95%:1.18;4.28; p for interaction=0.014 and triple negative tumors (OR=2.93(CI95%:1.12-7.63; the intake of plant foods in postmenopausal women (OR=2.35(CI95%:1.24;4.44 and triple negative tumors (OR=3.48(CI95%:1.46-8.31; and the alcohol consumption in ER+/PR+&HER2- tumors (OR=1.52 (CI95%:1.06-2.19 showed the strongest associations.Breast cancer prevention might be possible by following the "World Cancer Research Fund" and the

  10. What Is Lung Cancer? (United States)

    ... Graphics Infographic Stay Informed Cancer Home What Is Lung Cancer? Language: English Español (Spanish) Recommend on Facebook Tweet ... cancer starts in the lungs, it is called lung cancer. Lung cancer begins in the lungs and may ...

  11. Building capacity for clinical research in developing countries: the INDOX Cancer Research Network experience. (United States)

    Ali, Raghib; Finlayson, Alexander; Indox Cancer Research Network


    Transnational Organisations increasingly prioritise the need to support local research capacity in low and middle income countries in order that local priorities are addressed with due consideration of contextual issues. There remains limited evidence on the best way in which this should be done or the ways in which external agencies can support this process.We present an analysis of the learning from the INDOX Research Network, established in 2005 as a partnership between the Institute of Cancer Medicine at the University of Oxford and India's top nine comprehensive cancer centres. INDOX aims to enable Indian centres to conduct clinical research to the highest international standards; to ensure that trials are developed to address the specific needs of Indian patients by involving Indian investigators from the outset; and to provide the training to enable them to design and conduct their own studies. We report on the implementation, outputs and challenges of simultaneously trying to build capacity and deliver meaningful research output.

  12. A New Phase in Cancer Research at CERN

    CERN Multimedia


    The first meeting of the ENLIGHT network, set up to co-ordinate the development of light ion cancer therapy projects in Europe, took place at CERN last week. This is a form of therapy ideally suited to the treatment of deep-seated tumours and those near critical organs. Hans Hoffmann, Director for Technology transfer and scientific computing, and Director General Luciano Maiani during the opening of the first meeting of the ENLIGHT network that was held at CERN last week. The fruit of several years of work, this meeting offers new hope for the treatment of certain types of cancer. Around 70 specialists, including radiotherapists, oncologists, physicists and engineers, got together at CERN for the first meeting of a European cancer therapy research network named ENLIGHT (European Network for research in LIGHt ion Therapy(1)). This initiative, headed by oncologists and funded by the European Commission, aims to promote the development of light ion (hadron) therapy projects. The choice of CERN as a venue for ...

  13. Integration of Translational Research in the European Organization for Research and Treatment of Cancer Research (EORTC) Clinical Trial Cooperative Group Mechanisms.

    NARCIS (Netherlands)

    F. Lehmann (Frederick); D. Lacombe (Denis); A.M.M. Eggermont (Alexander)


    textabstractThe landscape for cancer research is profoundly different today from that only one decade ago. Basic science is moving rapidly and biotechnological revolutions in molecular targeting and immunology have completely modified the opportunities and concepts for cancer treat

  14. Recent progress in 8igenomic research of liver cancer

    Institute of Scientific and Technical Information of China (English)


    Along the course of occurrence and development of liver cancer,the corresponding somatic cells accumulate some important genetic variations.These variations may be divided into two categories.For the genetic changes closely related to etiology of liver cancer,the well-known cases include insertion and integration of the hepatitis B virus(HBV) DNA after infection,and mutations at site 249 of the tumor suppressor gene p53 induced by exposure to aflatoxin B1.The secondary genetic changes include amplification and deletion of certain chromosome regions,mutations in p53 at the sites other than 249,as well as the mutational activation of the Wnt/β-catenin signal pathway.The tumor cells with these genetic variations may gradually become the dominant clones under evolutionary selection.Besides,identification of genetic susceptible against risk of liver malignancy is also an important aspect of research in this field.

  15. Recent progress in 8igenomic research of liver cancer

    Institute of Scientific and Technical Information of China (English)

    HAN ZeGuang


    Along the course of occurrence and development of liver cancer, the corresponding somatic cells ac-cumulate some important genetic variations. These variations may be divided into two categories. For the genetic changes closely related to etiology of liver cancer, the well-known cases include insertion and integration of the hepatitis B virus (HBV) DNA after infection, and mutations at site 249 of the tumor suppressor gene p53 induced by exposure to aflatoxin B1. The secondary genetic changes include amplification and deletion of certain chromosome regions, mutations in p53 at the sites other than 249, as well as the mutational activation of the Wnt/β-catenin signal pathway. The tumor cells with these genetic variations may gradually become the dominant clones under evolutionary selection. Besides, identification of genetic susceptible against risk of liver malignancy is also an important aspect of re-search in this field.

  16. Research Progress of Lung Cancer with Leptomeningeal Metastasis

    Directory of Open Access Journals (Sweden)

    Chunhua MA


    Full Text Available Leptomeningeal metastases is one of the most serious complications of lung cancer, the patients with poor prognosis. Leptomeningeal metastasis in patients with lack specificity of clinical manifestations. The main clinical performance are the damage of cerebral symptoms, cranial nerve and spinal nerve. The diagnosis primarily based on the history of tumor, clinical symptoms, enhance magnetic resnance image (MRI scan and cerebrospinal fluid cytology. In recent years, new ways of detecting clinically, significantly increase the rate of early detection of leptomeningeal metastases. The effect of comprehensive treatments are still sad. The paper make a review of research progress in pathologic physiology, clinical manifestations, diagnosis methods and treatments of lung cancer with leptomeningeal metastases.

  17. Placing "Knowledge" in Teacher Education in the English Further Education Sector: An Alternative Approach Based on Collaboration and Evidence-Based Research (United States)

    Loo, Sai Y.


    This paper focuses on teacher education in the English further education sector, where the teaching of disciplinary and pedagogic knowledge is an issue. Using research findings, the paper advocates an approach based on collaboration and informed research to emphasize and integrate knowledge(s) in situated teaching contexts despite working in a…

  18. Reading Sources and Academic Freedom as Determinants of Trends in English Language Teacher Research in Egypt: An Interview-Based Study (United States)

    Abdel Latif, Muhammad M. M.


    Little attention has been given to investigating the experiences of teacher researchers while undertaking their studies. In an attempt to explore what accounts for the stereotyped and imitative trends in the studies conducted by English language teachers in Egypt, the present study has explored how they select research topics and the factors…

  19. A Good Foundation for Number Learning for Five-Year-Olds? An Evaluation of the English Early Learning "Numbers" Goal in the Light of Research (United States)

    Gifford, Sue


    This article sets out to evaluate the English Early Years Foundation Stage Goal for Numbers, in relation to research evidence. The Goal, which sets out to provide "a good foundation in mathematics", has greater breadth of content and higher levels of difficulty than previous versions. Research suggests that the additional expectations…

  20. College English Classification Teaching Analysis--Private College English Teaching Research and Practice%大学英语分级教学分析--民办高校大学英语教学研究与实践

    Institute of Scientific and Technical Information of China (English)



    当今各行各业国际化的趋势越来越明显,伴随而来的英语全球化的发展趋势越来越快。今天,全世界大约有四分之一的人在说英语,英语已经成为名符其实的全球通用语言。当前国内高校都很重视英语教学,并对英语教学提出了越来越高的要求。传统的英语教学时针对的是行政班级,基本“一刀切”。然教学时面对的教学对象必然是有差别的。因而,笔者鉴于民办高校学生的学习基础,学习能力等实情,选择部分学生开展了关于民办高校英语分级教学的研究和实践,探索了当前民办高校大学英语教学模式的改革,并通过实践,总结了关于大学英语分级教学在民办高校中的优势和一些亟待解决的问题。%Today all walks of international trends are becoming evident, accompanied by English globalization trends faster. Today, about a quarter of the world's people speak English, English has become a truly universal language. Current domestic universities attach great importance to the teaching of English and English teaching increasingly high requirements. Tradi-tional English teaching is for the executive class, the basic is"one size fits all."Teaching object and then face the inevitable teaching there is a difference. Thus, the author's view of private college students learn the basics, learn the facts ability to se-lect some students to carry out research and practice on college English Teaching Private explore the current reform of college English teaching model of private universities, and through practice, summed up on college English teaching at private col-leges in the advantages and some problems to be solved.

  1. Adherence to the World Cancer Research Fund/American Institute for Cancer Research guidelines and risk of death in Europe : results from the European Prospective Investigation into Nutrition and Cancer cohort study

    NARCIS (Netherlands)

    Vergnaud, Anne-Claire; Romaguera, Dora; Peeters, Petra H.; van Gils, Carla H.; Chan, Doris S. M.; Romieu, Isabelle; Freisling, Heinz; Ferrari, Pietro; Clavel-Chapelon, Francoise; Fagherazzi, Guy; Dartois, Laureen; Li, Kuanrong; Tikk, Kaja; Bergmann, Manuela M.; Boeing, Heiner; Tjonneland, Anne; Olsen, Anja; Overvad, Kim; Dahm, Christina C.; Luisa Redondo, Maria; Agudo, Antonio; Sanchez, Maria-Jose; Amiano, Pilar; Chirlaque, Maria-Dolores; Ardanaz, Eva; Khaw, Kay-Tee; Wareham, Nick J.; Crowe, Francesca; Trichopoulou, Antonia; Orfanos, Philippos; Trichopoulos, Dimitrios; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Ros, Martine M.; May, Anne; Wirfalt, Elisabet; Sonestedt, Emily; Johansson, Ingegerd; Hallmans, Goeran; Lund, Eiliv; Weiderpass, Elisabete; Parr, Christine L.; Riboli, Elio; Norat, Teresa


    Background: In 2007, the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) issued recommendations on diet, physical activity, and weight management for cancer prevention on the basis of the most comprehensive collection of available evidence. Objective: We inves

  2. Adherence to the World Cancer Research Fund/American Institute for Cancer Research guidelines and risk of death in Europe: results from the European Prospective Investigation into Nutrition and Cancer cohort study1,4

    NARCIS (Netherlands)

    Vergnaud, A.C.; Romaguera, D.; Peeters, P.H.M.; Gils, C.H. van; Chan, D.S.; Romieu, I.; Freisling, H.; Ferrari, P.; Clavel-Chapelon, F.; Fagherazzi, G.; Dartois, L.; Li, K.; Tikk, K.; Bergmann, M.M.; Boeing, H.; Tjonneland, A.; Olsen, A.; Overvad, K.; Dahm, C.C.; Redondo, M.L.; Agudo, A.; Sanchez, M.J.; Amiano, P.; Chirlaque, M.D.; Ardanaz, E.; Khaw, K.T.; Wareham, N.J.; Crowe, F.; Trichopoulou, A.; Orfanos, P.; Trichopoulos, D.; Masala, G.; Sieri, S.; Tumino, R.; Vineis, P.; Panico, S.; Bueno-De-Mesquita, H.B.; Ros, M.M.; May, A.; Wirfalt, E.; Sonestedt, E.; Johansson, I.; Hallmans, G.; Lund, E.; Weiderpass, E.; Parr, C.L.; Riboli, E.; Norat, T.


    BACKGROUND: In 2007, the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) issued recommendations on diet, physical activity, and weight management for cancer prevention on the basis of the most comprehensive collection of available evidence. OBJECTIVE: We inves

  3. Differential Regulatory Analysis Based on Coexpression Network in Cancer Research

    Directory of Open Access Journals (Sweden)

    Junyi Li


    Full Text Available With rapid development of high-throughput techniques and accumulation of big transcriptomic data, plenty of computational methods and algorithms such as differential analysis and network analysis have been proposed to explore genome-wide gene expression characteristics. These efforts are aiming to transform underlying genomic information into valuable knowledges in biological and medical research fields. Recently, tremendous integrative research methods are dedicated to interpret the development and progress of neoplastic diseases, whereas differential regulatory analysis (DRA based on gene coexpression network (GCN increasingly plays a robust complement to regular differential expression analysis in revealing regulatory functions of cancer related genes such as evading growth suppressors and resisting cell death. Differential regulatory analysis based on GCN is prospective and shows its essential role in discovering the system properties of carcinogenesis features. Here we briefly review the paradigm of differential regulatory analysis based on GCN. We also focus on the applications of differential regulatory analysis based on GCN in cancer research and point out that DRA is necessary and extraordinary to reveal underlying molecular mechanism in large-scale carcinogenesis studies.

  4. Multi-modality molecular imaging for gastric cancer research (United States)

    Liang, Jimin; Chen, Xueli; Liu, Junting; Hu, Hao; Qu, Xiaochao; Wang, Fu; Nie, Yongzhan


    Because of the ability of integrating the strengths of different modalities and providing fully integrated information, multi-modality molecular imaging techniques provide an excellent solution to detecting and diagnosing earlier cancer, which remains difficult to achieve by using the existing techniques. In this paper, we present an overview of our research efforts on the development of the optical imaging-centric multi-modality molecular imaging platform, including the development of the imaging system, reconstruction algorithms and preclinical biomedical applications. Primary biomedical results show that the developed optical imaging-centric multi-modality molecular imaging platform may provide great potential in the preclinical biomedical applications and future clinical translation.

  5. Cancer research in Brazil - stuck in second gear?

    Directory of Open Access Journals (Sweden)

    A.P. Lepique


    Full Text Available This article describes the main issues regarding clinical cancer research in Brazil, including both the opportunities and the hurdles. Scientists and clinicians in this field had the opportunity to talk to regulatory agencies and to the Health Ministry representative at a meeting held in the State of Rio de Janeiro, Brazil, in April 2014. Our conclusions are that we do indeed have opportunities; however, we need to move forward regarding partnerships between academia and industry, increase the availability of funding, and provide easier navigation through the regulatory processes.

  6. Barrett's Esophagus Translational Research Network (BETRNet) | Division of Cancer Prevention (United States)

    The goal of BETRNet is to reduce the incidence, morbidity, and mortality of esophageal adenocarcinoma by answering key questions related to the progression of the disease, especially in the premalignant stage. In partnership with NCI’s Division of Cancer Biology, multidisciplinary translational research centers collaborate to better understand the biology of Barrett's esophagus and esophageal adenocarcinoma to improve risk stratification and develop prevention strategies.  | Multi-disciplinary, multi-institutional collaboration to enhance understanding of Barrett's esophagus and to prevent esophageal adenocarcinoma.

  7. Research on Oral English Teaching%英语口语教学探究

    Institute of Scientific and Technical Information of China (English)



    Oral language should be phased in different ages, people in different ages have different oral categories; oral English emphasis on communication, oral language teaching must be based on listening to expand the information. Oral teaching is not iso- lated, it must pay attention to listening training. Advanced spoken language requires comprehensive skills, natural and even less from literacy training; Integrated reading and writing will help raise the level of spoken English. This paper studies the dialectical thinking of oral teaching, to address the oral teaching activities, integrated, thematic and practical issues.%口语应该分阶,不同年龄阶段的口语范畴应该是不一样的;口语注重交流,口语教学要建立在听取信息的情况下去展开。口语教学不是孤立的,它须重视听力训练。高级的口语要求综合的表达能力,自然更离不开读写训练;综合的读写训练有利于英语口语水平的提高。本文研究的是口语教学辩证的思想,旨在解决口语教学的活动性、综合性、专题性与实效性的问题。

  8. Does science need a global language? English and the future of research

    CERN Document Server

    Montgomery, Scott L


    In early 2012, the global scientific community erupted with news that the elusive Higgs boson had likely been found, providing potent validation for the Standard Model of how the universe works. Scientists from more than one hundred countries contributed to this discovery-proving, beyond any doubt, that a new era in science had arrived, an era of multinationalism and cooperative reach. Globalization, the Internet, and digital technology all play a role in making this new era possible, but something more fundamental is also at work. In all scientific endeavors lies the ancient drive for sharing ideas and knowledge, and now this can be accomplished in a single tongue - English. But is this a good thing? In "Does Science Need a Global Language?", Scott L. Montgomery seeks to answer this question by investigating the phenomenon of global English in science, how and why it came about, the forms in which it appears, what advantages and disadvantages it brings, and what its future might be. He also examines the cons...

  9. Impact of biospecimens handling on biomarker research in breast cancer

    Directory of Open Access Journals (Sweden)

    Callari Maurizio


    Full Text Available Abstract Background Gene expression profiling is moving from the research setting to the practical clinical use. Gene signatures able to correctly identify high risk breast cancer patients as well as to predict response to treatment are currently under intense investigation. While technical issues dealing with RNA preparation, choice of array platforms, statistical analytical tools are taken into account, the tissue collection process is seldom considered. The time elapsed between surgical tissue removal and freezing of samples for biological characterizations is rarely well defined and/or recorded even for recently stored samples, despite the publications of standard operating procedures for biological sample collection for tissue banks. Methods Breast cancer samples from 11 patients were collected immediately after surgical removal and subdivided into aliquots. One was immediately frozen and the others were maintained at room temperature for respectively 2, 6 and 24 hrs. RNA was extracted and gene expression profile was determined using cDNA arrays. Phosphoprotein profiles were studied in parallel. Results Delayed freezing affected the RNA quality only in 3 samples, which were not subjected to gene profiling. In the 8 breast cancer cases with apparently intact RNA also in sample aliquots frozen at delayed times, 461 genes were modulated simply as a function of freezing timing. Some of these genes were included in gene signatures biologically and clinically relevant for breast cancer. Delayed freezing also affected detection of phosphoproteins, whose pattern may be crucial for clinical decision on target-directed drugs. Conclusion Time elapsed between surgery and freezing of samples appears to have a strong impact and should be considered as a mandatory variable to control for clinical implications of inadequate tissue handling.

  10. [Reading nursing Literature in English: new inputs for practicing nurses]. (United States)

    von Klitzing, Waltraut; Stoll, Hansruedi; Trachsel, Edith; Aldorf, Kurt; Bernhard, Annelis; Eze, Germaine; Spirig, Rebecca


    A prerequisite to providing evidence-based care is the ability to comprehend the nursing research literature, most of which is published in English. To facilitate this understanding, a course on "reading the research literature for evidence-based practice in English" was developed by an interdisciplinary team for staff nurses at the University Hospital Basel. The pilot course was offered to nurses who specialized in cancer care. It was led by the oncology Advanced Practice Nurse (APN) from the Department of Medicine. Research articles focusing on the management of chronic illness and cancer pain management were assigned and read. The course consisted of ten 90 minute lessons. The evaluation was designed to address the following questions: 1. Did participation in the course improve the oncology related knowledge of the nurses? 2. Did participation in the course improve the nurses' English language skills? 3. At what level of difficulty did the nurse participants perceive the course to be? 4. Were course participants able to use their newly acquired knowledge to teach their nursing colleagues on the ward? The course evaluation demonstrated that the 15 participants significantly improved their oncology knowledge through this process but that their English skills did not improve. The participants were able to present lectures on their wards based on the course literature, which were positively evaluated by their colleagues and the APN course leader. The participants perceived the course as being sophisticated but also effective at demonstrating the use of English-language research literature for one's own nursing practice.

  11. Research on Immunotherapy: Using the Immune System to Treat Cancer (United States)

    ... cells that suppress immune responses. These advances in cancer immunotherapy are the result of long-term investments in ... Engineering Patients’ Immune Cells to Treat Their Cancers Cancer immunotherapy in children: How does it differ from approaches ...

  12. Assessing dentists' knowledge about oral cancer: translation and linguistic validation of a standardized questionnaire from American English into German. (United States)

    Hertrampf, Katrin; Wenz, Hans-Jürgen; Koller, Michael; Springer, Ingo; Jargot, Anke; Wiltfang, Jörg


    Oral cancer represents a considerable health problem with more than 10,000 new cases each year in Germany. Nevertheless, little information is available on the knowledge of dentists and the public on oral cancer. This project aims at investigating the knowledge and opinions of dentists via a questionnaire. The present article describes the translation process of an internationally accepted instrument into German. The translation was carried out by the Mapi Research Institute, Lyon, France. The translation procedure followed an established linguistic validation process, consisting of the conceptual analysis of the source instrument, a forward and backward translation, the clinicians' review, proofreading, and the finalization. The institute identified nine cultural adaptations. After forward and backward translations, the clinical reviewers suggested 16 stylistic changes, four alternative wordings, two more cultural adaptations, and five changes of nomenclature. After debriefing, the translated questionnaire involved nine stylistic changes, four alternative wordings, and 11 changes for cultural adaptation. The described translation and validation procedure guarantees a high-quality standard instrument for the evaluation of dentists' knowledge and opinions on oral cancer in Germany and prevents misinterpretations due to cultural differences, which allows an international comparison of the data.

  13. Implementation of tissue microarrays technique for cancer research in Cuba

    Directory of Open Access Journals (Sweden)

    Tania Lahera-Sánchez


    Full Text Available The tissue microarray (TMA technique is based on making cylindrical cores from paraffin donor blocks and transfer to a single recipient block. The TMA has revolutionized the field of pathology for the possibility to evaluate multiple samples in one slide. There is no precedent of this subject in Cuba, so the objective of this research was to implement the TMA technique. The concordance of the results obtained by complete section and the TMA were evaluated for this purpose, in the evaluation of the estrogen receptors (ER, progesterone (PR and epidermal growth factor type 2 (HER2 in samples of breast cancer. Forty-five paraffin-embedded samples from women diagnosed with breast cancer at the Institute of Oncology in 2012 were studied. Two TMA blocks were constructed, and subsequently the expression of markers ER, PR and HER2 was determined by immunohistochemistry, in the complete section of tissue and in the TMA. Kappa index was used for concordance analysis. A good concordance was obtained for all three markers (ER k=0.8272; PR k=0.793 and HER2 k=0.716. This study constitutes the first report on the TMA technique in Cuba and shows that it is a valuable tool, suggesting its potential use in translational research and clinical trials on vaccines.

  14. Stem cell research: paths to cancer therapies and regenerative medicine. (United States)

    Weissman, Irving


    Most tissues in complex metazoans contain a rare subset of cells that, at the single-cell level, can self-renew and also give rise to mature daughter cells. Such stem cells likely in development build tissues and are retained in adult life to regenerate them. Cancers and leukemias are apparently not an exception: rare leukemia stem cells and cancer stem cells have been isolated that contain all of the tumorigenicity of the whole tumor, and it is their properties that will guide future therapies. None of this was apparent just 20 years ago, yet this kind of stem cell thinking already provides new perspectives in medical science and could usher in new therapies. Today, political, religious, and ethical issues surround embryonic stem cell and patient-specific pluripotent stem cell research and are center stage in the attempts by governments to ban these fields for discovery and potential therapies. These interventions require physicians and physician-scientists to determine for themselves whether patient welfare or personal ethics will dominate in their practices, and whether all aspects of stem cell research can be pursued in a safe and regulated fashion.

  15. Collaborative Research in Childhood Cancer Survivorship: The Current Landscape. (United States)

    Bhatia, Smita; Armenian, Saro H; Armstrong, Gregory T; van Dulmen-den Broeder, Eline; Hawkins, Michael M; Kremer, Leontien C M; Kuehni, Claudia E; Olsen, Jørgen H; Robison, Leslie L; Hudson, Melissa M


    Survivors of childhood cancer carry a substantial burden of morbidity and are at increased risk for premature death. Furthermore, clear associations exist between specific therapeutic exposures and the risk for a variety of long-term complications. The entire landscape of health issues encountered for decades after successful completion of treatment is currently being explored in various collaborative research settings. These settings include large population-based or multi-institutional cohorts and single-institution studies. The ascertainment of outcomes has depended on self-reporting, linkage to registries, or clinical assessments. Survivorship research in the cooperative group setting, such as the Children's Oncology Group, has leveraged the clinical trials infrastructure to explore the molecular underpinnings of treatment-related adverse events, and to understand specific complications in the setting of randomized risk-reduction strategies. This review highlights the salient findings from these large collaborative initiatives, emphasizing the need for life-long follow-up of survivors of childhood cancer, and describing the development of several guidelines and efforts toward harmonization. Finally, the review reinforces the need to identify populations at highest risk, facilitating the development of risk prediction models that would allow for targeted interventions across the entire trajectory of survivorship.

  16. Public involvement in breast cancer research: an analysis and model for future research. (United States)

    McCormick, Sabrina; Brody, Julia; Brown, Phil; Polk, Ruth


    Public involvement in health program planning has been taking place for many years, and has provided a precedent for the emergence of public involvement in research conducted since the early 1990s. Such involvement is now widely seen in breast cancer research, due to the large public concern and major social movement activity. This article reviews current practices and general models of public involvement in research and constructs a prototype. The authors interviewed researchers, program officers, and laypeople in order to understand the obstacles, processes, and benefits. They conclude that public involvement has major ramifications for the democratization of science and the construction of knowledge by teaching lay people about science and sensitizing researchers to concerns of the public. There is growing support on the part of scientists and government agents for public involvement.

  17. A Rough Research on Numerical Cultural Connotations between English and Chinese

    Institute of Scientific and Technical Information of China (English)



    Numerals are closely related to our daily life. We can not measure time, price, proportion, victory or defeat without numerals. However, numerals are not only take effects in calculation and other relevant respects in mathematics, but also function as mysterious cultural signs sometimes. In the long process of the Chinese nation's development, almost every number has formed its own meaning with its distinctive characteristics. Numerals' invention and applying is an important symbol of human beings' cultural development. So they can not be ignored in the culture of human language. Nevertheless, various connotative meanings are bestowed on various numerals by different nations mainly owing to the discrepancies in historical backgrounds, social customs, religions culture, ideology between English and Chinese. This paper mainly explores the relationship between people's conventional concept to numerals and nations' culture, studies the background knowledge of their cultural sources in the two languages, so as to know cultural differences and eliminate cultural conflict and improve people's inter-cultural communication.

  18. Research on Situational Teaching of Junior Middle English Class from the Perspective of Life-orientation

    Institute of Scientific and Technical Information of China (English)

    FANG Jin-ming


    The regression of instruction to life raises as a developmental tendency of course reform among the world. Emphasis on the connection between instruction and students’lives has become an important aspect of curriculum reform. The student learner’s role and the development of students’potentials in their lives also have been emphasized;all these conceptions provide broad space for the implementation of life-orientation of instruction. Situational teaching emphasizes that students should be re-garded as the nucleus of the class. Through acquiring knowledge by themselves, they can bear the knowledge in their mind and improve their communicating ability. The teaching activity should always obey the rule of students centered and teacher aided and make sure that the teaching atmosphere can be kept in an authentic situation. And the most important thing that will be talk-ed about is how to apply situational teaching in Junior Middle English Class.

  19. The Ideological Construction of English: A Critical Review on the Discourse of English in East Asia (United States)

    Lin, Han-Yi


    This research investigates the ideological character of the English language in East Asia. It focuses on the prevailing beliefs, values and propositions relating to English as a global language and the spread of English in the non-English East Asian countries, namely China, Japan, South Korea and Taiwan. By analyzing how English is presented in…

  20. 英语写作教学研究初探%Research on Teaching of English Writing

    Institute of Scientific and Technical Information of China (English)



    本文就我国英语写作教学中的结果教学法、过程教学法、体裁教学法、写长法的理论依据及它们的优点和缺点进行了简单的评价,同时指出了现在语料库在教学研究和写作中的应用。%This paper discusses some important teaching approaches in English writing,such as the Product Approach,the Process Approach,The Genre Approach,Length Approach and their theoretical basis.It also evaluates their advantages and disadvantages.It points out corpus applications in the teaching research.

  1. Identifying Indonesian-core vocabulary for teaching English to Indonesian preschool children: a corpus-based research

    Directory of Open Access Journals (Sweden)

    Maryani .


    Full Text Available This corpus-based research focuses on building a corpus of Indonesian children’s storybooks to find the frequent content words in order to identify Indonesian-core vocabulary for teaching English to Indonesian preschool children. The data was gathered from 131 Indo¬nesian children’s storybooks, which resulted in a corpus of 134,320 words. These data were run through a frequency menu in MonoConc Pro, a corpus program. Data analysis was analyzed by selecting the frequent nouns, verbs, adjectives, and adverbs before each of them was lemmatized. The result showed that the children were already exposed to both ordinary and imaginative concepts, antonym in adjective, time reference, and compound nouns. The narrative discourse clearly influenced the kind of verbs the children exposed to

  2. Assessing tobacco use by cancer patients and facilitating cessation: an American Association for Cancer Research policy statement. (United States)

    Toll, Benjamin A; Brandon, Thomas H; Gritz, Ellen R; Warren, Graham W; Herbst, Roy S


    When diagnosed with cancer, patients can immediately make a meaningful positive impact on their health by stopping their tobacco use. Scientific evidence clearly shows that tobacco use in patients with cancer leads to poorer outcomes. The specific biological processes driving tobacco consumption's interference in cancer therapy are the subject of continuing research, but the evidence is clear that tobacco use in patients with cancer leads to decreased treatment efficacy and safety, decreased survival, decreased quality of life, increased treatment-related toxicity, and increased risk of cancer recurrence and second primary tumors. Data suggest that tobacco cessation can improve outcomes and survival in patients with cancer, yet full execution of evidence-based cessation interventions is infrequent in oncology settings. Therefore, both improved provision of cessation assistance to all patients with cancer who use tobacco or have recently quit and further study of the deleterious effects of tobacco use and benefits of tobacco cessation on cancer progression and treatment are needed and recommended by the American Association for Cancer Research. Progress on both fronts begins with universal assessment and documentation of tobacco use as a standard of quality cancer care regardless of treatment setting and will be further facilitated through the development of reliable, valid, and standard measures of tobacco use, incorporation of evidence-based procedures into quality and accreditation procedures, and the development of appropriate training, clinical infrastructure, and incentives for delivery of tobacco cessation interventions.


    Institute of Scientific and Technical Information of China (English)

    NiuQiang; MartinWolff


    A great deal has been written and said about various approaches to the successful methodology for teaching English as a foreign/second language in China. Entire professional journals are devoted to the subject, such as Teaching English In China (now called CELEA Journal ), and Foreign Language Teaching and Research, to name a couple. But no matter how much is written, and no matter what teaching method is employed ; the bottom line is that the average Chinese student learns to orally communicate in Chinglish i. e. Mandarin sprinkled with English or English with Mandarin induced syntax.

  4. Redes En Acción. Increasing Hispanic participation in cancer research, training, and awareness. (United States)

    Ramirez, Amelie G; Talavera, Gregory A; Marti, Jose; Penedo, Frank J; Medrano, Martha A; Giachello, Aida L; Pérez-Stable, Eliseo J


    Hispanics are affected by many health care disparities. The National Cancer Institute (NCI), through its Special Populations Branch, is supporting networking and capacity-building activities designed to increase Hispanic participation and leadership in cancer research. Redes En Acción established a national network of cancer research centers, community-based organizations, and federal partners to facilitate opportunities for junior Hispanic scientists to participate in training and research projects on cancer control. Since 2000, Redes En Acción has established a network of more than 1800 Hispanic leaders involved in cancer research and education. The project has sustained 131 training positions and submitted 29 pilot projects to NCI for review, with 16 awards for a total of $800,000, plus an additional $8.8 million in competing grant funding based on pilot study results to date. Independent research has leveraged an additional $32 million in non-Redes funding, and together the national and regional network sites have participated in more than 1400 community and professional awareness events. In addition, the program conducted extensive national survey research that provided the basis for the Redes En Acción Latino Cancer Report, a national agenda on Hispanic cancer issues. Redes En Acción has increased participation in cancer control research, training, and awareness among Hispanic scientists and within Hispanic communities. Cancer 2006. (c) 2006 American Cancer Society.


    Institute of Scientific and Technical Information of China (English)

    张喜平; 苏丹; 程琪辉


    S To provide evidences for exploiting tissue microarray (TMA) technology, we reviewed advantages and applications of TMA on tumor research. TMA has many advantages, including (1) section from TMA blocks can be utilized for the simultaneous analysis of up to 1,000 different tumors at DNA, RNA or protein level; (2) TMA is highly representative of their donor tissues; (3) TMA can improve conservation of tissue resources and experimental reagents, improve internal experimental control, and increase sample numbers per experiment, and can be used for large-scale, massively parallel in situ analysis; (4) TMA facilitates rapid translation of molecular discoveries to clinical applications. TMA has been applied to tumor research, such as glioma, breast tumor, lung cancer and so on. The development of novel biochip technologies has opened up new possibilities for the high-throughput molecular profiling of human tumors. Novel molecular markers emerging from high-throughput expression surveys could be analyzed on tumor TMA. It is anticipated that TMA, a new member of biochip, will soon become a widely used tool for all types of tissue-based research. TMA will lead to a significant acceleration of the transition of basic research findings into clinical applications.

  6. Multidisciplinary Meeting on Male Breast Cancer : Summary and Research Recommendations

    NARCIS (Netherlands)

    Korde, Larissa A.; Zujewski, Jo Anne; Kamin, Leah; Giordano, Sharon; Domchek, Susan; Anderson, William F.; Bartlett, John M. S.; Gelmon, Karen; Nahleh, Zeina; Bergh, Jonas; Cutuli, Bruno; Pruneri, Giancarlo; McCaskill-Stevens, Worta; Gralow, Julie; Hortobagyi, Gabriel; Cardoso, Fatima


    Male breast cancer is a rare disease, accounting for less than 1% of all breast cancer diagnoses worldwide. Most data on male breast cancer comes from small single-institution studies, and because of the paucity of data, the optimal treatment for male breast cancer is not known. This article summari

  7. Cancer patient and survivor research from the cancer information service research consortium: a preview of three large randomized trials and initial lessons learned. (United States)

    Marcus, Alfred C; Diefenbach, Michael A; Stanton, Annette L; Miller, Suzanne M; Fleisher, Linda; Raich, Peter C; Morra, Marion E; Perocchia, Rosemarie Slevin; Tran, Zung Vu; Bright, Mary Anne


    The authors describe 3 large randomized trials from the Cancer Information Service Research Consortium. Three web-based multimedia programs are being tested to help newly diagnosed prostate (Project 1) and breast cancer patients (Project 2) make informed treatment decisions and breast cancer patients prepare for life after treatment (Project 3). Project 3 also tests a telephone callback intervention delivered by a cancer information specialist. All participants receive standard print material specific to each project. Preliminary results from the 2-month follow-up interviews are reported for the initial wave of enrolled participants, most of whom were recruited from the Cancer Information Service (1-800-4-CANCER) telephone information program (Project 1: n =208; Project 2: n =340; Project 3: n =792). Self-reported use of the multimedia program was 51%, 52%, and 67% for Projects 1, 2, and 3, respectively. Self-reported use of the print materials (read all, most, or some) was 90%, 85%, and 83% for Projects 1, 2, and 3, respectively. The callback intervention was completed by 92% of Project 3 participants. Among those using the Cancer Information Service Research Consortium interventions, perceived usefulness and benefit was high, and more than 90% reported that they would recommend them to other cancer patients. The authors present 5 initial lessons learned that may help inform future cancer communications research.

  8. Emergent Teacher-Researchers: A Reflection on the Challenges Faced when Conducting Research in the English Classroom (United States)

    Blakemore, Helen


    The following narrative reflects on the dilemmas and problems faced by inexperienced researchers working within the field of education. Focusing on a research project completed in fulfilment of an MA in Teaching and Learning, the article recounts the decisions made by one emergent researcher and evaluates how far the chosen methods may have helped…

  9. Improving Content Assessment for English Language Learners: Studies of the Linguistic Modification of Test Items. Research Report. ETS RR-14-23 (United States)

    Young, John W.; King, Teresa C.; Hauck, Maurice Cogan; Ginsburgh, Mitchell; Kotloff, Lauren; Cabrera, Julio; Cavalie, Carlos


    This article describes two research studies conducted on the linguistic modification of test items from K-12 content assessments. In the first study, 120 linguistically modified test items in mathematics and science taken by fourth and sixth graders were found to have a wide range of outcomes for English language learners (ELLs) and non-ELLs, with…

  10. Approaches to Writing Instruction for Adolescent English Language Learners: A Discussion of Recent Research and Practice Literature in Relation to Nationwide Standards on Writing (United States)

    Panofsky,Carolyn; Pacheco, Maria; Smith, Sara; Santos, Janet; Fogelman, Chad; Harrington, Margaret; Kenney, Erica


    English language learners (ELLs) in today's U.S. middle schools and high schools face significant challenges from state writing assessments, and data suggest that they do not fare well. This paper seeks to uncover some of the reasons by posing the question: What is the available research base and practice literature to help teachers prepare ELLs…

  11. Funding in English Universities and Its Relationship to the Research Excellence Framework (United States)

    Kelly, Anthony


    The purpose of the Research Excellence Framework (REF) is to judge the quality of research in the UK and on that basis to apportion to universities, in a transparent manner, differential shares in the UK's £1.6 billion pot of research funding. However, the funding process is anything but transparent! While the REF process was known years in…

  12. Research on Fast Track Surgery Application in Lung Cancer Surgery

    Directory of Open Access Journals (Sweden)

    Kaiyun YANG


    Full Text Available Background and objective Fast track surgery (FTS is a systematical method to accelerate the recovery of surgical patients by reducing the physical and mental trauma stress of them. The research is to investigate the feasibility of FTS application in lung cancer surgery. Methods A total of 80 cases of lung cancer patients with single leaf lobotomy resection were randomized into two groups. While the experimental group was treated with the conception of FTS, and the control group was treated with the traditional methods. The incident rate of post-operation pain degrees, telecasts, pleural effusion, the post-operation time stay in hospital time and the total cost during hospitalization in two groups were compared respectively. Results In FTS group: the VAS score of post-operation pain at 1 h, 6 h, 12 h, 24 h and 48 h all significantly decreased compared to the traditional therapy group. The incidence rate of telecast was 10.53%. The incidence rate of pleural effusion was 26.31%. The length of stay after operation was (4±1 d and the total cost was RMB 15 600±7 600. In the control group, the above values were 77.78%, 33.33%, 22.22%, (9±1 d, RMB 23 600±5 400, respectively. The post operation pain (VAS method of FTS group was remarkablely below the control group. There has significant difference of the incident rate of telecasts, stay time in hospital and the total cast in two groups (P < 0.05. No significant difference was observed in the incident rate of pleural effusion. Conclusion The new methods of FTS can apparently accelerates recovery after lung cancer resection, reduces complications, shorten timestay in hospital and cut down the total cost.

  13. Chinese English Learners' Strategic Competence (United States)

    Wang, Dianjian; Lai, Hongling; Leslie, Michael


    The present study aims to investigate Chinese English learners' ability to use communication strategies (CSs). The subjects are put in a relatively real English referential communication setting and the analyses of the research data show that Chinese English learners, when encountering problems in foreign language (FL) communication, are…

  14. Leveraging epidemiology and clinical studies of cancer outcomes: recommendations and opportunities for translational research. (United States)

    Elena, Joanne W; Travis, Lois B; Simonds, Naoko I; Ambrosone, Christine B; Ballard-Barbash, Rachel; Bhatia, Smita; Cerhan, James R; Hartge, Patricia; Heist, Rebecca S; Kushi, Lawrence H; Lash, Timothy L; Morton, Lindsay M; Onel, Kenan; Pierce, John P; Robison, Leslie L; Rowland, Julia H; Schrag, Deborah; Sellers, Thomas A; Seminara, Daniela; Shu, Xiao Ou; Thomas, Nancy E; Ulrich, Cornelia M; Freedman, Andrew N


    As the number of cancer survivors continues to grow, research investigating the factors that affect cancer outcomes, such as disease recurrence, risk of second malignant neoplasms, and the late effects of cancer treatments, becomes ever more important. Numerous epidemiologic studies have investigated factors that affect cancer risk, but far fewer have addressed the extent to which demographic, lifestyle, genomic, clinical, and psychosocial factors influence cancer outcomes. To identify research priorities as well as resources and infrastructure needed to advance the field of cancer outcomes and survivorship research, the National Cancer Institute sponsored a workshop titled "Utilizing Data from Cancer Survivor Cohorts: Understanding the Current State of Knowledge and Developing Future Research Priorities" on November 3, 2011, in Washington, DC. This commentary highlights recent findings presented at the workshop, opportunities to leverage existing data, and recommendations for future research, data, and infrastructure needed to address high priority clinical and research questions. Multidisciplinary teams that include epidemiologists, clinicians, biostatisticians, and bioinformaticists will be essential to facilitate future cancer outcome studies focused on improving clinical care of cancer patients, identifying those at high risk of poor outcomes, and implementing effective interventions to ultimately improve the quality and duration of survival.

  15. Growth Analysis of Cancer Biology Research, 2000-2011

    Directory of Open Access Journals (Sweden)



    Full Text Available Methods and Material: The PubMed database was used for retrieving data on 'cancer biology.' Articles were downloaded from the years 2000 to 2011. The articles were classified chronologically and transferred to a spreadsheet application for analysis of the data as per the objectives of the study. Statistical Method: To investigate the nature of growth of articles via exponential, linear, and logistics tests. Result: The year wise analysis of the growth of articles output shows that for the years 2000 to 2005 and later there is a sudden increase in output, during the years 2006 to 2007 and 2008 to 2011. The high productivity of articles during these years may be due to their significance in cancer biology literature, having received prominence in research. Conclusion: There is an obvious need for better compilations of statistics on numbers of publications in the years from 2000 to 2011 on various disciplines on a worldwide scale, for informed critical assessments of the amount of new knowledge contributed by these publications, and for enhancements and refinements of present Scientometric techniques (citation and publication counts, so that valid measures of knowledge growth may be obtained. Only then will Scientometrics be able to provide accurate, useful descriptions and predictions of knowledge growth.

  16. Research progress in the treatment of small cell lung cancer (United States)

    Qiu, Yan-fang; Liu, Zhi-gang; Yang, Wen-juan; Zhao, Yu; Tang, Jiao; Tang, Wei-zhi; Jin, Yi; Li, Fang; Zhong, Rui; Wang, Hui


    Small cell lung cancer (SCLC) accounts for approximately 10-15% of all lung cancers. No significant improvement has been made for patients with SCLC in the past several decades. The main progresses were the thoracic radiation and prophylactic cranial irradiation (PCI) that improved the patient survival rate. For patients with limited disease and good performance status (PS), concurrent chemoradiotherapy (CCRT) followed by PCI should be considered. For extensive disease, the combination of etoposide and platinum-based chemotherapy remains the standard treatment and consolidative thoracic radiotherapy is beneficial for patients who have a significant respond to initial chemotherapy. However, the prognosis still remains poor. Recently, efforts have been focused on molecular targets and immunotherapy. But numerous molecular targets methods have failed to show a significant clinical benefit in patients with SCLC. It is anticipated that further development of research will depend on the on-going trials for molecular targeted therapy and immunotherapy which are promising and may improve the outcomes for SCLC in the next decade.

  17. Motivating teachers in the developing world: Insights from research with English language teachers in Oman (United States)

    Wyatt, Mark


    According to some commentators, targets set by the international community for bringing education to all children in developing countries are threatened by a teacher motivation crisis. For this crisis to be addressed, challenges to the motivation of teachers in such contexts need to be understood from perspectives both theoretical and comparative. Thus an analysis is required of the changes that have taken place particularly in countries whose education systems have developed rapidly in recent decades. Case studies of motivated teacher behaviour in such national contexts might be of relevance to educational reformers. Drawing upon the tenets of self-determination theory (SDT), this article begins by discussing the nature of the reported teacher motivation crisis in the developing world more generally. It then focuses on the Sultanate of Oman, highlighting recent historical developments there. Having thus set the scene, the author considers the extent to which negative environmental influences on teacher motivation in Oman have been addressed and then looks for evidence of intrinsic motivation in case studies of Omani English teachers. Returning to the developing world more generally, conclusions focus on how teachers' psychological needs for competence, autonomy and relatedness can be met through educational policies that reduce negative influences on teacher motivation and provide both inspiring professional development opportunities and work environments characterised by respect.

  18. Evaluation of speech outcomes using English version of the Speech Handicap Index in a cohort of head and neck cancer patients. (United States)

    Dwivedi, Raghav C; St Rose, Suzanne; Chisholm, Edward J; Bisase, Brian; Amen, Furrat; Nutting, Christopher M; Clarke, Peter M; Kerawala, Cyrus J; Rhys-Evans, Peter H; Harrington, Kevin J; Kazi, Rehan


    The aim of this study was to explore post-treatment speech impairments using English version of Speech Handicap Index (SHI) (first speech-specific questionnaire) in a cohort of oral cavity (OC) and oropharyngeal (OP) cancer patients. Sixty-three consecutive OC and OP cancer patients in follow-up participated in this study. Descriptive analyses have been presented as percentages, while Mann-Whitney U-test and Kruskall-Wallis test have been used for the quantitative variables. Statistical Package for Social Science-15 statistical software (SPSS Inc., Chicago, IL) was used for the statistical analyses. Over a third (36.1%) of patients reported their speech as either average or bad. Speech intelligibility and articulation were the main speech concerns for 58.8% and 52.9% OC and 31.6% and 34.2% OP cancer patients, respectively. While feeling of incompetent and being less outgoing were the speech-related psychosocial concerns for 64.7% and 23.5% OC and 15.8% and 18.4% OP cancer patients, respectively. Worse speech outcomes were noted for oral tongue and base of tongue cancers vs. tonsillar cancers, mean (SD) values were 56.7 (31.3) and 52.0 (38.4) vs. 10.9 (14.8) (Pspeech in HNC patients. Over one-third of OC and OP cancer patients reported speech problems in their day-do-day life. Advanced T-stage tumors affecting the oral tongue or base of tongue are particularly associated with poor speech outcomes.

  19. Highlights of recent developments and trends in cancer nanotechnology research--view from NCI Alliance for Nanotechnology in Cancer. (United States)

    Hull, L C; Farrell, D; Grodzinski, P


    Although the incidence of cancer and cancer related deaths in the United States has decreased over the past two decades due to improvements in early detection and treatment, cancer still is responsible for a quarter of the deaths in this country. There is much room for improvement on the standard treatments currently available and the National Cancer Institute (NCI) has recognized the potential for nanotechnology and nanomaterials in this area. The NCI Alliance for Nanotechnology in Cancer was formed in 2004 to support multidisciplinary researchers in the application of nanotechnology to cancer diagnosis and treatment. The researchers in the Alliance have been productive in generating innovative solutions to some of the central issues of cancer treatment including how to detect tumors earlier, how to target cancer cells specifically, and how to improve the therapeutic index of existing chemotherapies and radiotherapy treatments. Highly creative ideas are being pursued where novelty in nanomaterial development enables new modalities of detection or therapy. This review highlights some of the innovative materials approaches being pursued by researchers funded by the NCI Alliance. Their discoveries to improve the functionality of nanoparticles for medical applications includes the generation of new platforms, improvements in the manufacturing of nanoparticles and determining the underlying reasons for the movement of nanoparticles in the blood.

  20. Learning English

    Institute of Scientific and Technical Information of China (English)

    欧华倩; 林璀瑜


    Some of my classmates are afrald ot English. They think English is difficult to learn. But I don't think so. I like English very much. To me, it's not only a subject, but also a useful language. I try my best to use English at any time if possible.

  1. World Englishes

    Institute of Scientific and Technical Information of China (English)

    张严心; 周丽


    In the current days, the search for information and the need for global communication have already promoted English from being the language of people in different countries as the international language. This essay will give some arguments about the inevitability of variety of world Englishes and its characteristics, and then explain that what Standard English is and examples about the standards in English.

  2. Stakeholder engagement for comparative effectiveness research in cancer care: experience of the DEcIDE Cancer Consortium. (United States)

    Greenberg, Caprice C; Wind, Jennifer K; Chang, George J; Chen, Ronald C; Schrag, Deborah


    Stakeholder input is a critical component of comparative effectiveness research. To ensure that the research activities of the Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Network, supported by the Agency for Healthcare Research and Quality, translate into the greatest impact for everyday practice and policy-making in cancer, we were tasked with soliciting stakeholder input regarding priority areas in cancer-related comparative effectiveness research for the DEcIDE Cancer Consortium. Given the increasing emphasis on stakeholder engagement in research, many investigators are facing a similar task, yet there is limited literature to guide such efforts, particularly in cancer care. To help fill this gap, we present our approach to operationalizing stakeholder engagement and discuss it in the context of other recent developments in the area. We describe challenges encountered in convening stakeholders from multiple vantage points to prioritize topics and strategies used to mitigate these barriers. We offer several recommendations regarding how to best solicit stakeholder input to inform comparative effectiveness research in cancer care. These recommendations can inform other initiatives currently facing the challenges of engaging stakeholders in priority setting for cancer.

  3. English in Vietnam and Its Features

    Institute of Scientific and Technical Information of China (English)

    李琼璐; 张婷


    English spoken by people from different countries takes on different characteristics. Many linguists conducted researches on World Englishes. Focusing on the pronunciation, grammar, vocabulary and literature achievement, these studies present the target English's environment and features. However, there is rare achievement of English in Vietnam. Under the economy boom, Vietnamese government attached importance to the English education, which led to the wide utilization of English. This article analyzes English in Vietnam and its features , including pronunciation, grammar and vocabulary, in the hope of making complements to world Englishes.

  4. Tobacco and cancer: an American Association for Cancer Research policy statement. (United States)

    Viswanath, Kasisomayajula; Herbst, Roy S; Land, Stephanie R; Leischow, Scott J; Shields, Peter G


    The evidence against tobacco use is clear, incontrovertible, and convincing; so is the need for urgent and immediate action to stem the global tide of tobacco-related death and suffering and to improve public health. The American Association for Cancer Research makes an unequivocal call to all who are concerned about public health to take the following immediate steps:Increase the investment in tobacco-related research, commensurate with the enormous toll that tobacco use takes on human health, to provide the scientific evidence to drive the development of effective policies and treatments necessary to dramatically reduce tobacco use and attendant disease. Develop new evidence-based strategies to more effectively prevent the initiation of tobacco use, especially for youth and young adults. Promote the further development of evidence-based treatments for tobacco cessation, including individualized therapies, and ensure coverage of and access to evidence-based behavioral and pharmacological treatments. Develop evidence-based strategies for more effective public communication to prevent, reduce, and eliminate tobacco use and to guide health policies and clinical practice. Develop effective, evidence-based policies to reduce disparities across the tobacco continuum among social groups and developed and developing nations. Implement to the fullest extent existing evidence-based, systems-wide tobacco control programs to prevent initiation and foster cessation. Adapt and implement appropriate approaches to reduce the growing burden of tobacco use in the developing world. Enhance and coordinate surveillance efforts, both in the United States and globally, to monitor tobacco products, tobacco use, and tobacco-related disease, including tobacco use in oncology clinical trials. Establish a comprehensive, science-based regulatory framework to evaluate tobacco products and manufacturers' claims. Promote research that addresses the following: the potential harms of current and

  5. From Reductionism to Holism: Systems-oriented Approaches in Cancer Research. (United States)

    Kienle, Gunver; Kiene, Helmut


    Somatic mutation theory of cancer has directed cancer research during the last century. A deluge of information on cellular, molecular, and genetic behavior was uncovered, but so was a mind-numbing complexity that still challenges research and concepts, and expectations in the war on cancer have by and large not been fulfilled. A change of paradigm beyond reductionism has been called for, especially as research ubiquitously points at the importance of tissue, microenvironment, extracellular matrix, embryonic and morphogenetic fields, and fields of tissue maintenance and organization in the processes of carcinogenesis, cancer control, and cancer progression, as well as in the control of cellular and genetic behavior. Holistic, organismic systems concepts open new perspectives for cancer research and treatment, as well as general biological understanding.

  6. 新课改下农村中学的英语校本教研%English School-based Teaching Research in Rural Middle School in New Curriculum Reform

    Institute of Scientific and Technical Information of China (English)



    In order to realize professional development of English teachers and promote new English curriculum reform, teachers should probe into constructing English school-based teaching research pattern adapting to new curriculum.%为了实现英语教师的专业成长,有力地推进英语新课程改革,教师应探索建立与新课程相适应的英语校本教研方式。

  7. The Role Transform for the English Teaching Researchers with the Sense of the New Curriculum

    Institute of Scientific and Technical Information of China (English)



    As the curriculum reform of the basic education is developing in depth continuously, what Changes of the position and function for the teaching and research organizations will take place? And how to propell the curriculttm reform of the basic education is a real problem for every teaching and research worker to concern. During the procedure.edure of the basic

  8. Handbook of Research on Teaching the English Language Arts. Second Edition. (United States)

    Flood, James, Ed.; Lapp, Diane, Ed.; Squire, James R., Ed.; Jensen, Julie M., Ed.

    This updated second edition reflects developments in educational research and new information within the areas of language learning and instruction since the publication of the first edition in 1991. Its 75 essays assess the significance of research, evaluates new developments, and examines current conflicts, controversies, and issues, while…

  9. The Nature and Trends in Research and Journal Literature in English Speaking Africa. (United States)

    Alemna, Anaba; Badu, Ellis


    Describes a study that examined three major international library science journals to investigate the nature and trends of library and information science research in Africa from 1990 through 1992. Highlights include status of authors, gender, affiliation, country, types of research, types of cited documents, subjects covered, and most cited…

  10. Realising and Extending Stenhouse's Vision of Teacher Research: The Case of English History Teachers (United States)

    Fordham, Michael


    Stenhouse's original vision of teacher research incorporated a strong emphasis on curriculum construction, interpretation and evaluation. This curricular emphasis is less prevalent in the present in the dominant "professional development" and "what works" traditions of teacher research. It is shown here, however, that this…

  11. The Language Lessons around Us: Undergraduate English Pedagogy and Linguistic Landscape Research (United States)

    Chesnut, MIchael; Lee, Vivian; Schulte, Jenna


    This narrative article analyses three Korean undergraduate students' experiences conducting a linguistic landscape research project. Linguistic landscape research, the study of publicly displayed language such as billboards and other signs, is a relatively new area of scholarly interest. However, there has been only limited study of using…

  12. [The application of CRISPR/Cas9 genome editing technology in cancer research]. (United States)

    Wang, Dayong; Ma, Ning; Hui, Yang; Gao, Xu


    The CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein-9 nuclease) genome editing technology has become more and more popular in gene editing because of its simple design and easy operation. Using the CRISPR/Cas9 system, researchers can perform site-directed genome modification at the base level. Moreover, it has been widely used in genome editing in multiple species and related cancer research. In this review, we summarize the application of the CRISPR/Cas9 system in cancer research based on the latest research progresses as well as our understanding of cancer research and genome editing techniques.

  13. DCP's Early Detection Research Guides Future Science | Division of Cancer Prevention (United States)

    Early detection research funded by the NCI's Division of Cancer Prevention has positively steered both public health and clinical outcomes, and set the stage for findings in the next generation of research. |

  14. Setting a Health Policy Research Agenda for Controlling Cancer Burden in Korea


    Jang, Sung-In; Cho, Kyoung-hee; Kim, Sun Jung; Lee, Kwang-Sig; Park, Eun-Cheol


    Purpose The aim of study was to provide suggestions for prioritizing research in effort to reduce cancer burden in Korea based on a comprehensive analysis of cancer burden and Delphi consensus among cancer experts. Materials and Methods Twenty research plans covering 10 topics were selected based on an assessment of the literature, and e-mail surveys were analyzed using a two-round modified Delphi method. Thirty-four out of 79 experts were selected from four organizations to participate in ro...

  15. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Cancers Metastatic Cancer Recurrent Cancer Research NCI’s Role in Cancer Research Intramural Research Extramural Research Bioinformatics and ... Annual Report to the Nation Cancer Snapshots Milestones in Cancer Research and Discovery Stories of Discovery R& ...

  16. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Adult Cancers Metastatic Cancer Recurrent Cancer Research NCI’s Role in Cancer Research Intramural Research Extramural Research Bioinformatics ... Terminology Resources NCI Data Catalog Cryo-EM NCI's Role in Cancer Research Intramural Research Extramural Research Bioinformatics ...

  17. What's New in Prostate Cancer Research and Treatment? (United States)

    ... of MRI (such as diffusion weighted imaging [DWI], dynamic contrast enhanced [DCE] MRI, or MR spectroscopy). The ... Please share your thoughts about your website experience. If you need immediate cancer-related information ...

  18. Director's Update - Office of Cancer Clinical Proteomics Research (United States)

    The National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (NCI-CPTAC) has recently begun the proteomic interrogation of genomically-characterized tumors from The Cancer Genome Atlas.

  19. What's New in Laryngeal and Hypopharyngeal Cancer Research and Treatment? (United States)

    ... that blocks EGFR, is sometimes used to treat cancers of larynx and hypopharynx. Other EGFR blockers are under study for use in head and neck cancers, including panitumumab (Vectibix ® ), lapatinib (Tykerb ® ), and erlotinib (Tarceva ® ). ...

  20. Prostate Cancer Research Training in Health Disparities for Minority Undergraduates (United States)


    that may be associated with prostate cancer . The overlap between environment and diet, toxicology , exposure assessment, risk assessment/risk...of the Vanderbilt Ingram Cancer Center. She completed her doctoral training in the Department of Pharmacology and Toxicology at the University of...Microbiology and Immunology , and Associate Professor of Cancer Biology at Vanderbilt University. He earned the MBBS (MD) degree from Ahmadu Bello

  1. Computational Omics - Office of Cancer Clinical Proteomics Research (United States)

    The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium (CPTAC) and the NVIDIA Foundation are pleased to announce funding opportunities in the fight against cancer. Each organization has launched a request for proposals (RFP) that will collectively fund up to $2 million to help to develop a new generation of data-intensive scientific tools to find new ways to treat cancer.

  2. TRANSLATE: New Strategic Approaches for English Learners (United States)

    Goodwin, Amanda P.; Jiménez, Robert


    This teaching tip shares a research-based instructional model that uses translation to improve the English reading comprehension of English Learners. Within this instruction, English learners work collaboratively in small groups and use translation to facilitate understandings of their required English language arts curriculum. Students are taught…

  3. The Validity of SAT® Scores in Predicting First-Year Mathematics and English Grades. Research Report 2012-1 (United States)

    Mattern, Krista D.; Patterson, Brian F.; Kobrin, Jennifer L.


    This study examined the validity of the SAT for predicting performance in first-year English and mathematics courses. Results reveal a significant positive relationship between SAT scores and course grades, with slightly higher correlations for mathematics courses compared to English courses. Correlations were estimated by student characteristics…

  4. English as an Additional Language--A Genealogy of Language-in-Education Policies and Reflections on Research Trajectories (United States)

    Leung, Constant


    The school population in England is linguistically diverse; according to official data, over one million pupils do not speak English as their first language. All teachers are expected to support English as an additional language (EAL) development as part of their professional responsibility. At the same time, there has been little specific…

  5. The International Corpus of Learner English: A New Resource for Foreign Language Learning and Teaching and Second Language Acquisition Research. (United States)

    Granger, Sylviane


    Describes the design of the International Corpus of Learner English, outlining the learner and task variables in the corpus of texts written by English-as-a-Foreign-Language university undergraduates. The design of the corpus and sampling of students with different native languages make contrastive interlanguage analyses and error analyses…

  6. Research and Practice of the System of Computer-assisted Oral English Test on a Large Scale

    Institute of Scientific and Technical Information of China (English)

    Bo Jiang


      The establishment of computer-assisted oral test system is one way to improve college students’ English communication skills. This thesis gives a brief analysis of how to set up a scientific system in colleges from the characters of oral activities,oral ability and its features,the patterns of English oral test and the abilities tested.

  7. An Empirical Research of Chinese Learners' Acquisition of the English Article System--Based on Syntactic Misanalysis Account (United States)

    Jian, Shi


    In the field of applied linguistics, the English article is the acknowledged teaching and learning difficulty and receives lots of attention in second language acquisition (SLA). This paper, based on the Syntactic Misanalysis Account (SMA) advocated by Trenkic in which L2 articles are analyzed as adjectives by L2ers, proposes the English article…

  8. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Information Advance Directives Using Trusted Resources Cancer Types Adolescents and Young Adults with Cancer Reports, Research, and ... of Cancers Cancers by Body Location Childhood Cancers Adolescent & Young Adult Cancers Metastatic Cancer Recurrent Cancer Research ...

  9. The research on English Teaching in the network environment%网络环境中英语教学的探究

    Institute of Scientific and Technical Information of China (English)



    The information network teaching has been more and more schools and social concerns of English teaching in today’s highly information-oriented,how to make the students to make good use of the network to master the English language,English educators face the issue.Network teaching is a new teaching model and means it will have a significant impact on the traditional English teaching.A wealth of teaching resources in the network environment,open teaching mode provides a good environment for English teaching. English Teaching of reading,writing,heard and research learning a new impetus to the development in IT support,so that the students‘enthusiasm for learning has been an unprecedented increase and converted quickly improve students’ English literacy.Network technology and English curriculum integration has gradually infiltrated into the teaching of various disciplines,educators are teaching theory and practice,delve into the network context of instructional design,teaching strategies,to form a new teaching model to promote English teaching changes.From English teaching mode to the network,the changes in the pattern of English learners,English teaching changes in the means of three levels of English teaching of the network information analysis and elaboration.%  网络信息化教学已越来越受到学校和社会的关注,而英语教学在高度信息化的今天,怎样使学生运用好网络来掌握英语,就成为英语教育工作者所要面对的课题。网络教学是全新的教学模式和手段,它将对传统的英语教学产生重大的影响。网络环境下丰富的教学资源、开放的教学模式为英语教学提供了良好的环境。英语教学中学生的阅读、写作、听说和研究性学习等内容在信息技术的支持下获得了新的发展动力,使学生的学习积极性得到了空前的提高并转化为学生英语素养的迅速提高。网络技术与英语课程的整合已经逐步渗入到

  10. The Cervix Cancer Research Network (CCRN: Increasing access to cancer clinical trials in low- and middle-income countries

    Directory of Open Access Journals (Sweden)

    Gita eSuneja


    Full Text Available Introduction: The burden of cervical cancer is large and growing in developing countries, due in large part to limited access to screening services and lack of human papillomavirus (HPV vaccination. In spite of modern advances in diagnostic and therapeutic modalities, outcomes from cervical cancer have not markedly improved in recent years. Novel clinical trials are urgently needed to improve outcomes from cervical cancer worldwide. Methods: The Cervix Cancer Research Network (CCRN, a subsidiary of the Gynecologic Cancer InterGroup (GCIG, is a multi-national, multi-institutional consortium of physicians and scientists focused on improving cervical cancer outcomes worldwide by making cancer clinical trials available in low-, middle-, and high-income countries. Standard operating procedures for participation in CCRN include a pre-qualifying questionnaire to evaluate clinical activities and research infrastructure, followed by a site visit. Once a site is approved, they may choose to participate in one of four currently accruing clinical trials.Results: To date, 13 different CCRN site visits have been performed. Of these 13 sites visited, 10 have been approved as CCRN sites including Tata Memorial Hospital, India; Bangalore, India; Trivandrum, India; Ramathibodi, Thailand; Siriaj, Thailand; Pramongkutklao, Thailand; Ho Chi Minh, Vietnam; Blokhin Russian Cancer Research Center; the Hertzen Moscow Cancer Research Institute; and the Russian Scientific Center of Roentgenoradiology. The four currently accruing clinical trials are TACO, OUTBACK, INTERLACE, and SHAPE.Discussion: The CCRN has successfully enrolled 10 sites in developing countries to participate in four randomized clinical trials. The primary objectives are to provide novel therapeutics to regions with the greatest need and to improve the validity and generalizability of clinical trial results by enrolling a diverse sample of patients.

  11. California Breast Cancer Prevention Initiatives: Setting a research agenda for prevention. (United States)

    Sutton, P; Kavanaugh-Lynch, M H E; Plumb, M; Yen, I H; Sarantis, H; Thomsen, C L; Campleman, S; Galpern, E; Dickenson, C; Woodruff, T J


    The environment is an underutilized pathway to breast cancer prevention. Current research approaches and funding streams related to breast cancer and the environment are unequal to the task at hand. We undertook the California Breast Cancer Prevention Initiatives, a four-year comprehensive effort to set a research agenda related to breast cancer, the environment, disparities and prevention. We identified 20 topics for Concept Proposals reflecting a life-course approach and the complex etiology of breast cancer; considering the environment as chemical, physical and socially constructed exposures that are experienced concurrently: at home, in the community and at work; and addressing how we should be modifying the world around us to promote a less carcinogenic environment. Redirecting breast cancer research toward prevention-oriented discovery could significantly reduce the incidence and associated disparities of the disease among future generations.

  12. Cancer Patient and Survivor Research from the Cancer Information Service Research Consortium: A Preview of Three Large Randomized Trials and Initial Lessons Learned (United States)



    Three large randomized trials are described from the Cancer Information Service Research Consortium (CISRC). Three web-based multimedia programs are being tested to help newly diagnosed prostate (Project 1) and breast cancer patients (Project 2) make informed treatment decisions and breast cancer patients prepare for life after treatment (Project 3). Project 3 is also testing a telephone callback intervention delivered by a cancer information specialist. All participants receive standard print material specific to each project. Preliminary results from the two-month follow-up interviews are reported for the initial wave of enrolled participants, most of whom were recruited from the Cancer Information Service (1-800-4-CANCER) telephone information program (Project 1 = 208, Project 2 = 340, Project 3 = 792). Self-reported use of the multimedia program was 51%, 52% and 67% for Projects 1–3, respectively. Self-reported use of the print materials (read all, most or some) was 90%, 85% and 83% for Projects 1–3, respectively. The callback intervention was completed by 92% of Project 3 participants. Among those using the CISRC interventions, perceived utility and benefit was high, and more than 90% would recommend them to other cancer patients. Five initial lessons learned are presented that may help inform future cancer communications research. PMID:23448232

  13. An Action Research for High School English Teachers Training%英语教师研修模式的行动研究

    Institute of Scientific and Technical Information of China (English)

    黄佩君; 黄泽锐


    Education Action Research,originated from the self-reflection teaching approch,is a pedagogical research method,which has always been advocated by the education experts at home and abroad.This paper defines the model of action research on the high school English teachers based on the analysis of the content of action research.This action research model helps to enhance high school English teachers'abilities of handling their education problems about English teaching at their schools and strengthen the practical effectiveness of the training program for high school English teachers,which has great significance on directing foreign language teaching and research.%基于自我反思教学模式发展而来的教育行动研究是国内外教育界专家倡导实践的研究方法.本文在阐述行动研究定义的基础上,分析了英语教师行动研究模式的基本内涵.行动研究模式引导教师寻找解决英语课堂教学问题的方法并运用到实际教学情境中,解决实际教学问题的一种有效的研修方法,有助于提高英语教师解决实际教学问题的能力,增强研修的实效性.

  14. 论英专低年级学生英语写作中母语负迁移问题%Research of Negative Transfer from Mother Tongue on English Major Sophomore Group English writings

    Institute of Scientific and Technical Information of China (English)

    田梦丹; 朱明慧; 徐冬梅


    语言迁移理论作为二语习得研究的重要组成部分,一直是热点话题之一。通过分析学生的英语作文,可以发现母语是如何对二语学习者产生负迁移影响的。该文运用错误分析理论对收集的英语专业低年级组30名学生的写作作品进行统计和分析,并从词法、句法和语用角度分析错误类型,旨在帮助学生最大程度地减少母语负迁移的影响,最终提高学生的英语水平。%As an important part of second language acquisition research, language migration theory has been one of the hot topics. By analyzing the students' English compositions, we can discover how the mother tongue exerts negative transfer influences on second language learners. In this paper, English major sophomore group of 30 students’writings are analyzed from the perspec-tives of the lexical, syntactic and pragmatic errors by using the theory of error analysis, aiming at decreasing negative transfer and promoting their English level at last.

  15. Moving forward in colorectal cancer research, what proteomics has to tell

    Institute of Scientific and Technical Information of China (English)


    Colorectal cancer is the third most common cancer and is highly fatal. During the last several years, research has been primarily based on the study of expression profiles using microarray technology. But now, investigators are putting into practice proteomic analyses of cancer tissues and cells to identify new diagnostic or therapeutic biomarkers for this cancer. Because the proteome reflects the state of a cell, tissue or organism more accurately, much is expected from proteomics to yield better tumor markers for disease diagnosis and therapy monitoring. This review summarizes the most relevant applications of proteomics the biomarker discovery for colorectal cancer.

  16. An Action Research on How to Improve English Reading Abilities of Students in High School

    Institute of Scientific and Technical Information of China (English)

    王文韬; 于月清; 程雯


    This dissertation is based on the characteristics of high school students' reading ability and the latest tendency of curriculum reforms of nation to carry out my action research. Firstly, propose a hypothetical analysis and utilize questionnaire, interviewing, teacher log and student log to collect and analyze information with the aim of verifying the hypothesis. Secondly, Work out an effective action research scheme and carry it out. In the process of carrying out the scheme, I reflect and ameliorate my scheme constantly in order to maximize students' reading ability and raise students' speed. This dissertation is divided into six parts.

  17. English Teaching Strategies Research--Based on the Vocational High School Art Students’Learning Style

    Institute of Scientific and Technical Information of China (English)

    Sun Jianxia


    Diagnosing learners' learning style is meaningful for “student-centered” teaching mode and individualized teaching.But the teaching strategies based on the students' learning style should gain the same attention.Seldom do researchers regard vocational high school art students as their subjects.Using Reid’s Perceptual Learning Style Survey as the research instrument, this paper viewed vocational high school art students as the subjects;the purpose is to find some effective strategies to teach art students of vocational high school well.

  18. Research of Job Scenario-based English in High Vocational English Teaching%高职英语职场情景化教学的研究

    Institute of Scientific and Technical Information of China (English)



    Higher vocational English teaching aims at adapting to the occupational application demand of enterprises and learners, and the job scenario-based teaching just can embody the requirement of practical English ability needed by job. Implementing job scenario-based teaching should select teaching resource in advance, and make preparation for scenario task before class. At the same time, it needs to have job scenario-based teaching in class and practical class well.%高职英语教学的目的是为了适应企业和学习者的职业应用需要,而职场情景化教学恰恰能在教学中体现出职场所需的实用性英语能力要求。实施职场情景化教学,要提前选择教学资源,做好课前情景任务准备,同时要分别上好课堂上职场情景化教学和实践课堂上的教学。

  19. Leadership of Schools as Research-Led Organisations in the English Educational Environment: Cultivating a Research-Engaged School Culture (United States)

    Godfrey, David


    This article examines the conditions for the growth and expansion of research-engaged schools in England. The current policy climate is seeing a rapid growth of autonomous schools coupled with the continuing tendency to hold schools to account for overall student educational attainment indicators. Within this context, the article begins by…

  20. Analyzing research article introductions by Iranian and native English-speaking authors of Applied Linguistics

    Directory of Open Access Journals (Sweden)

    Shahriari Ahmadi, Hesamoddin


    Full Text Available Considering the role of academic writing in the dissemination of research findings among members of scientific communities, efforts have been made by language specialists to achieve a more detailed understanding of this register, with hopes that the derived features could then be used to teach researchers, writing in a second/foreign language, to more effectively communicate the results of their studies. This study sets out to achieve a similar goal through the analysis of research article introductions in terms of the frequency and function of their lexical bundles. To this end, a corpus of 200 research article introductions by published authors in the field of Applied Linguistics was compared to a similar corpus by Iranian, non-native writers of the same field. The findings reveal that Iranian authors use more 4-word lexical bundles in their writing compared to their native-speaker counterparts. Syntactic and functional differences between the two corpora are introduced and implications for academic writing instructors are discussed in detail.

  1. Designing a Qualitative Research for Evaluation of English for Academic Purposes Activity in Teacher Education (United States)

    Zascerinska, Jelena


    Competence-based teacher education provides new knowledge within the knowledge triangle of education, research and innovation. Communicative competence is of the greatest importance which individuals need for personal fulfilment and development, active citizenship, social inclusion and employment (European Commission, 2004). The successful…

  2. A cloud-based data network approach for translational cancer research. (United States)

    Xing, Wei; Tsoumakos, Dimitrios; Ghanem, Moustafa


    We develop a new model and associated technology for constructing and managing self-organizing data to support translational cancer research studies. We employ a semantic content network approach to address the challenges of managing cancer research data. Such data is heterogeneous, large, decentralized, growing and continually being updated. Moreover, the data originates from different information sources that may be partially overlapping, creating redundancies as well as contradictions and inconsistencies. Building on the advantages of elasticity of cloud computing, we deploy the cancer data networks on top of the CELAR Cloud platform to enable more effective processing and analysis of Big cancer data.

  3. Conference Report: Eighth Annual AACR International Conference on Frontiers in Cancer Prevention Research. (United States)

    Brewster, Abenaa M; Patterson, Sherri L; Forman, Michele R; Hughes-Halbert, Chanita; Limburg, Paul J; Ondrey, Frank G; Paskett, Electra D; Wetter, David W; Hawk, Ernest T


    The Eighth Annual Frontiers in Cancer Prevention Research meeting was held in Houston, Texas, in November 2009. This report highlights significant presentations that advance the fields of chemoprevention, clinical trial recruitment and retention, cancer screening including optical imaging, energy balance, and nutritional epidemiology, and health communications and decision making. In findings from the randomized Reduction by Dutasteride of Prostate Cancer Events trial, dutasteride reduced the risk of biopsy-detectable prostate cancer in high-risk men by 23% compared with placebo. Important clues about the dosing and window of susceptibility for supplementation with choline, vitamin D, and folate were revealed from epigenetic research that has implications for future nutritional epidemiology research. Noninvasive optical imaging techniques using endoscopic ultrasound and autofluorescence for the early detection of cancers in the lung, pancreas, and oral cavity are being studied. The report also addresses the challenges of promoting cancer prevention. Understanding how individuals process risk information and make sustained behavior changes and the effect of socioeconomic status on health disparities were identified as critical areas of research. This multidisciplinary research meeting of basic, clinical, and behavioral scientists and epidemiologists continues to play a major role in identifying the research priority areas of cancer prevention, elucidating new mechanisms of carcinogenesis for targeted chemoprevention therapies and delivering a comprehensive strategy for engaging individuals in the unifying goal to reduce cancer incidence.

  4. Research in anxiety and its relationship with nursing English reading achievement%焦虑与护理英语阅读成绩的关系探讨

    Institute of Scientific and Technical Information of China (English)



    目的 了解焦虑与护理英语阅读成绩的关系,为民族地区医学院校护理英语阅读课程提供教学参考.方法 采用“护理英语阅读焦虑量表”设计问卷,收集护理英语阅读测试结果数据,对随机抽取的百色市某医学院校261名护生进行问卷调查.结果 护生护理英语阅读的焦虑状况处于高焦虑占19.9%,中焦虑占38.9%,低焦虑占41.2%.焦虑与护理英语阅读测试成绩成显著负相关.汉族和少数民族护生焦虑和护理英语阅读测试成绩比较差异显著.结论 应采取相应策略降低护生阅读焦虑,提高护理英语教学和学习效果.%Objective To find out the relationship between anxiety and nursing English reading achievement,and to provide references for teaching and learning of nursing English reading among ethnic minority region.Methods Nursing English Reading Anxiety Scale and nursing English reading tests were used to collect data,and 261 nursing students were chosen randomly from one of the Medical University in Baise as the research respondents.Results Students' anxiety level of nursing English reading was high (19.9%),medium (38.9%) and low (41.2%).Anxiety and nursing English reading achievement were negatively related.The Han nationality and ethnic minority students had significantly difference in the anxiety and nursing English reading achievement.Conclusions In order to improve the effectiveness of nursing English teaching and learning,the appropriate strategies to reduce the students' anxiety should be carried out.

  5. A breast cancer clinical registry in an Italian comprehensive cancer center: an instrument for descriptive, clinical, and experimental research. (United States)

    Baili, Paolo; Torresani, Michele; Agresti, Roberto; Rosito, Giuseppe; Daidone, Maria Grazia; Veneroni, Silvia; Cavallo, Ilaria; Funaro, Francesco; Giunco, Marco; Turco, Alberto; Amash, Hade; Scavo, Antonio; Minicozzi, Pamela; Bella, Francesca; Meneghini, Elisabetta; Sant, Milena


    In clinical research, many potentially useful variables are available via the routine activity of cancer center-based clinical registries (CCCR). We present the experience of the breast cancer clinical registry at Fondazione IRCCS "Istituto Nazionale dei Tumori" to give an example of how a CCCR can be planned, implemented, and used. Five criteria were taken into consideration while planning our CCCR: (a) available clinical and administrative databases ought to be exploited to the maximum extent; (b) open source software should be used; (c) a Web-based interface must be designed; (d) CCCR data must be compatible with population-based cancer registry data; (e) CCCR must be an open system, able to be connected with other data repositories. The amount of work needed for the implementation of a CCCR is inversely linked with the amount of available coded data: the fewer data are available in the input databases as coded variables, the more work will be necessary, for information technology staff, text mining analysis, and registrars (for collecting data from clinical records). A cancer registry in a comprehensive cancer center can be used for several research aspects, such as estimate of the number of cases needed for clinical studies, assessment of biobank specimens with specific characteristics, evaluation of clinical practice and adhesion to clinical guidelines, comparative studies between clinical and population sets of patients, studies on cancer prognosis, and studies on cancer survivorship.

  6. Linking Genealogical Research to Library and Information Science : Concepts, Perspectives, Considerations [English Brief Adaptation


    Sant-Geronikolou, Lia


    This essay is based on views and conclusions on genealogy and its relation to information sciences as shaped during long years of research inspired by both personal and experiental interest in the advanced study of family descent. It was a real challenge that, in order to become objectively comprehensive, I had to go beyond my personal preferences and practices, to the standards and culture of the best field professionals. It was progressively enriched in the process, along with the recons...

  7. An Investigation of English Writing Anxiety Among English Majors

    Institute of Scientific and Technical Information of China (English)



    With Daly, Horwitz and Y-S-Cheng’s theoretical model of second language writing anxiety as research framework, this thesis surveyed English majors’English writing anxiety. Findings of the present study show that all of the English major stu⁃dents experience English writing anxiety. There is no significant difference in English anxiety among students from three different grades. There is significant difference in English writing anxiety between the students who hold positive attitudes towards English writing and those who hold negative attitudes towards English writing and there is significant difference in English writing anxi⁃ety among students who rated their English writing good, average and bad. Results from the qualitative study show the reasons why there is little difference in English writing anxiety among students from three different grades. What’s more, it is shown that the poor writing skills, cognitive anxiety, test anxiety and erroneous beliefs toward English writing are the main sources of Eng⁃lish writing anxiety.

  8. Bioengineered models of solid human tumors for cancer research (United States)

    Marturano-Kruik, Alessandro; Villasante, Aranzazu; Vunjak-Novakovic, Gordana


    Summary The lack of controllable in vitro models that can recapitulate the features of solid tumors such as Ewing’s sarcoma limits our understanding of the tumor initiation and progression and impedes the development of new therapies. Cancer research still relies of the use of simple cell culture, tumor spheroids, and small animals. Tissue-engineered tumor models are now being grown in vitro to mimic the actual tumors in patients. Recently, we have established a new protocol for bioengineering the Ewing’s sarcoma, by infusing tumor cell aggregates into the human bone engineered from the patient’s mesenchymal stem cells. The bone niche allows crosstalk between the tumor cells, osteoblasts and supporting cells of the bone, extracellular matrix and the tissue microenvironment. The bioreactor platform used in these experiments also allows the implementation of physiologically relevant mechanical signals. Here, we describe a method to build an in vitro model of Ewing’s sarcoma that mimics the key properties of the native tumor and provides the tissue context and physical regulatory signals. PMID:27115504

  9. Cancer Research Center Indiana University School of Medicine

    Energy Technology Data Exchange (ETDEWEB)


    The Department of Energy (DOE) proposes to authorize the Indiana School of Medicine to proceed with the detailed design, construction and equipping of the proposed Cancer Research Center (CRC). A grant was executed with the University on April 21, 1992. A four-story building with basement would be constructed on the proposed site over a 24-month period. The proposed project would bring together, in one building, three existing hematology/oncology basic research programs, with improved cost-effectiveness through the sharing of common resources. The proposed site is currently covered with asphaltic pavement and is used as a campus parking lot. The surrounding area is developed campus, characterized by buildings, walkways, with minimal lawns and plantings. The proposed site has no history of prior structures and no evidence of potential sources of prior contamination of the soil. Environmental impacts of construction would be limited to minor increases in traffic, and the typical noises associated with standard building construction. The proposed CRC project operation would involve the use radionuclides and various hazardous materials in conducting clinical studies. Storage, removal and disposal of hazardous wastes would be managed under existing University programs that comply with federal and state requirements. Radiological safety programs would be governed by Nuclear Regulatory Commission (NRC) license and applicable Environmental Protection Agency (EPA) regulations. There are no other NEPA reviews currently active which are in relationship to this proposed site. The proposed project is part of a Medical Campus master plan and is consistent with applicable local zoning and land use requirements.

  10. 英语修辞格Pun与汉语双关语的互译研究%Research on English Pun and Chinese Pun Translation

    Institute of Scientific and Technical Information of China (English)



    双关语(Pun)是英语修辞格之一,深受广大文学家的青睐,其原理是利用一词多义、同音异义、同形异义的双关手段来达到多功能的修辞效果。在此,文章研究英语修辞Pun的分类及其修辞功能,从谐音双关和寓意双关两个方面探讨英语修辞格Pun与汉语双关语的互译,促进中国文学与英语文学的发展。%The pun (Pun) is one of the figures of English speech, many writers like to use it, its principle is to use the rhetoric effect of polysemy, homophone and homograph pun and achieves multiple functions of a word. This article researches the classification of English pun and its rhetorical function, and then explores the translation of English pun and Chinese pun from the two aspects of the homophonic pun and allegorical pun, finally promotes the development of Chinese literature and English literature.

  11. 英语语法学习中的母语迁移研究%Research on Mother Language Transfer in English Grammar Learning

    Institute of Scientific and Technical Information of China (English)



      母语迁移对于英语教学起着举足轻重的作用,是语言研究和语言教学研究的一个重要的问题,尤其表现在母语对英语语法学习中起到的干扰作用上。在学习英语语法的过程中有很多方面都涉及到了母语迁移问题。要想在语法教学中合理利用母语迁移理论我们必须正确认识母语在英语语法学习中的作用,并且全面地看待语法现象和母语迁移的关系,从而找到更合理合适的语法学习策略。%Mother language transfer plays an important part in English teaching. It is a significant subject in research of language and language teaching, especially in English grammar learning. It makes Chinese students confused. If we want to employ mother language transfer properly, we should understand its functions in English grammar learning properly, and understand the relationship between grammar and language transfer to find out suitable strategies of English grammar learning..

  12. Radiological English

    Energy Technology Data Exchange (ETDEWEB)

    Ribes, R. [Hospital Reina Sofia, Cordoba (Spain). Servicio de Radiologia; Ros, P.R. [Harvard Medical School, Boston, MA (United States). Div. of Radiology


    The book is an introductory book to radiological English on the basis that there are a lot of radiologists, radiology residents, radiology nurses, radiology students, and radiographers worldwide whose English level is indeterminate because their reading skills are much higher than their fluency. It is intended to help those health care professionals who need English for their work but do not speak English on a day-to-day basis. (orig.)

  13. Open-Access Cancer Genomics - Office of Cancer Clinical Proteomics Research (United States)

    The completion of the Human Genome Project sparked a revolution in high-throughput genomics applied towards deciphering genetically complex diseases, like cancer. Now, almost 10 years later, we have a mountain of genomics data on many different cancer type

  14. Research methods to change clinical practice for patients with rare cancers. (United States)

    Billingham, Lucinda; Malottki, Kinga; Steven, Neil


    Rare cancers are a growing group as a result of reclassification of common cancers by molecular markers. There is therefore an increasing need to identify methods to assess interventions that are sufficiently robust to potentially affect clinical practice in this setting. Methods advocated for clinical trials in rare diseases are not necessarily applicable in rare cancers. This Series paper describes research methods that are relevant for rare cancers in relation to the range of incidence levels. Strategies that maximise recruitment, minimise sample size, or maximise the usefulness of the evidence could enable the application of conventional clinical trial design to rare cancer populations. Alternative designs that address specific challenges for rare cancers with the aim of potentially changing clinical practice include Bayesian designs, uncontrolled n-of-1 trials, and umbrella and basket trials. Pragmatic solutions must be sought to enable some level of evidence-based health care for patients with rare cancers.

  15. Astronomy and Cancer Research: X-Rays and Nanotechnology from Black Holes to Cancer Therapy (United States)

    Pradhan, Anil K.; Nahar, Sultana N.

    It seems highly unlikely that any connection is to be found between astronomy and medicine. But then it also appears to be obvious: X-rays. However, that is quite superficial because the nature of X-rays in the two disciplines is quite different. Nevertheless, we describe recent research on exactly that kind of link. Furthermore, the linkage lies in atomic physics, and via spectroscopy which is a vital tool in astronomy and may also be equally valuable in biomedical research. This review begins with the physics of black hole environments as viewed through X-ray spectroscopy. It is then shown that similar physics can be applied to spectroscopic imaging and therapeutics using heavy-element (high-Z) moieties designed to target cancerous tumors. X-ray irradiation of high-Z nanomaterials as radiosensitizing agents should be extremely efficient for therapy and diagnostics (theranostics). However, broadband radiation from conventional X-ray sources (such as CT scanners) results in vast and unnecessary radiation exposure. Monochromatic X-ray sources are expected to be considerably more efficient. We have developed a new and comprehensive methodology—Resonant Nano-Plasma Theranostics (RNPT)—that encompasses the use of monochromatic X-ray sources and high-Z nanoparticles. Ongoing research entails theoretical computations, numerical simulations, and in vitro and in vivo biomedical experiments. Stemming from basic theoretical studies of Kα resonant photoabsorption and fluorescence in all elements of the Periodic Table, we have established a comprehensive multi-disciplinary program involving researchers from physics, chemistry, astronomy, pathology, radiation oncology and radiology. Large-scale calculations necessary for theory and modeling are done at a variety of computational platforms at the Ohio Supercomputer Center. The final goal is the implementation of RNPT for clinical applications.

  16. Breast Cancer in Young Women: Research Priorities. A Report of the Young Survival Coalition Research Think Tank Meeting. (United States)

    Korde, Larissa A; Partridge, Ann H; Esser, Michelle; Lewis, Stacy; Simha, Joy; Johnson, Rebecca H


    Breast cancer in young women is a significant issue-7% of all female breast cancer is diagnosed in women under 40 years of age. Young women with breast cancer (YWBC) face significant and unique challenges, including a higher likelihood of biologically aggressive disease and metastatic disease at diagnosis, leading to poorer prognosis, more aggressive treatment and long-term treatment-related toxicities, and unique psychosocial concerns. This article summarizes the Young Survival Coalition (YSC) Research Think Tank Meeting, held in Arlington, Virginia, in February 2013, and presents the process that led to YSC's priorities for YWBC research. The meeting's participants focused on six broad categories of investigation in which additional advancements in research on YWBC are crucial: risk factors; treatment; fertility; pregnancy-associated breast cancer; quality of life and survivorship; and metastasis. Several key themes emerged from this meeting. Researchers and advocates felt that a large-scale data registry focused on YWBC is necessary to collect quality information to guide future research for YWBC. This database should include clinical data, genomic profiling of primary tumor and metastatic sites, and an increased focus on fertility and pregnancy following breast cancer treatment. The participants also felt that more must be done to elucidate how and why YWBC develop more aggressive tumors, and to what degree treatment should be modified for young women. The discussions summarized here led to the formulation of YSC's Research Agenda, published in May 2014.

  17. Korean Adults' Attitudes towards Varieties of English


    Kim, Young Soo


    This study investigates 43 Korean adults’ attitudes towards native and non-native varieties of English in relation to the perspective of EIL (English as an international language). This study addresses three research questions: 1) do Korean adults prefer certain varieties of English? 2) do Korean adults at least accept non-native varieties of English?, and 3) are Korean adults aware of different varieties of English? In order to examine participants’ language attitudes, this study employed bo...

  18. Research in Sport and Exercise Psychology Between 2003 and 2013 : an Analysis of the English-Speaking Publication Trends Before the Field’s 50th Anniversary


    Németh, Lilla; Vega Marcos, Ricardo de la; Szabo, Attila


    Sports and exercise psychology as a scholastic field was officially inaugurated in 1965 in Rome on the occasion of the first World Congress on Sports Psychology. As it nears its 50th anniversary in 2015, we have conducted a content analysis of the existing six subject specific English-speaking international journals in the field to obtain an overview of research and publication trends. Articles (n = 2276) published between 1 January 2003 and 1 January 2013 were examined. The type of publicati...

  19. The Emergency Care of Patients With Cancer: Setting the Research Agenda. (United States)

    Brown, Jeremy; Grudzen, Corita; Kyriacou, Demetrios N; Obermeyer, Ziad; Quest, Tammie; Rivera, Donna; Stone, Susan; Wright, Jason; Shelburne, Nonniekaye


    To identify research priorities and appropriate resources and to establish the infrastructure required to address the emergency care of patients with cancer, the National Institutes of Health's National Cancer Institute and the Office of Emergency Care Research sponsored a one-day workshop, "Cancer and Emergency Medicine: Setting the Research Agenda," in March 2015 in Bethesda, MD. Participants included leading researchers and clinicians in the fields of oncology, emergency medicine, and palliative care, and representatives from the National Institutes of Health. Attendees were charged with identifying research opportunities and priorities to advance the understanding of the emergency care of cancer patients. Recommendations were made in 4 areas: the collection of epidemiologic data, care of the patient with febrile neutropenia, acute events such as dyspnea, and palliative care in the emergency department setting.

  20. Breast cancer research in Asia : Adopt or adapt Western knowledge?

    NARCIS (Netherlands)

    Bhoo-Pathy, Nirmala; Yip, Cheng-Har; Hartman, Mikael; Uiterwaal, Cuno S. P. M.; Devi, Beena C. R.; Peeters, Petra H. M.; Taib, Nur Aishah; van Gils, Carla H.; Verkooijen, Helena M.


    The incidence and mortality of breast cancer continues to rise rapidly in Asian countries. However, most of our current knowledge on breast cancer has been generated in Western populations. As the socio-economic profile, life style and culture of Asian and Western women are substantially different,

  1. What's New In Eye Cancer Research and Treatment? (United States)

    ... try to get it to attack the cancer. Cytokines, monoclonal antibodies, cancer vaccines, and other immunotherapies are among the most promising approaches for treating melanoma and lymphoma. Although most clinical trials of these treatments include people with melanomas of the skin and ...

  2. Translational Research on Esophageal Cancer: From Cell Line to Clinic

    NARCIS (Netherlands)

    J.J. Boonstra (Jurjen)


    textabstractWorldwide esophageal cancer is a signifi cant and an increasing health problem. In 2005, there were 497,700 new cases, and the prevalence is expected to increase by approximately 140% by 2025. Esophageal squamous cell carcinoma (ESCC) accounts for most of the cases of esophageal cancer w

  3. English in Vietnam and Its Features

    Institute of Scientific and Technical Information of China (English)

    李琼璐; 张婷


    English spoken by people from different countries takes on different characteristics. Many linguists conducted researches on World Englishes. Focusing on the pronunciation,grammar, vocabulary and literature achievement, these studies present the target English’s environment and features. However,there is rare achievement of English in Vietnam. Under the economy boom, Vietnamese government attached importance to the English education, which led to the wide utilization of English. This article analyzes English in Vietnam and its features,including pronunciation, grammar and vocabulary, in the hope of making complements to world Englishes.

  4. The Educational Narrative Research on College English Teachers%大学英语教师的教育叙事研究

    Institute of Scientific and Technical Information of China (English)



    我国大学英语教师专业发展的最佳途径是要把握教育叙事研究的基本特征和方法,叙事研究的基本环节和脉络并加以应用;通过叙事案例库和叙事研究平台的搭建,将大学英语教师的专业发展推向一个新台阶,为新时期大学英语教学改革提供有力保障.%In our country, the best way of college English teachers'major development needs to grasp the basic characteristics and skills of the narrative research , the basic link and context of narrative research and realize the application. We'll put the college English teachers'professional development into a new stage by building the database of narrative cases and research platform so as to provide guarantee for college English reform in the new era.

  5. A Cross-Cultural Perspective on Challenges Facing Comparative Cancer Survivorship Research

    Directory of Open Access Journals (Sweden)

    Astri Syse


    Full Text Available Cancer survivorship research includes the study of physical, psychosocial, and economic consequences of cancer diagnosis and treatment among pediatric and adult cancer survivors. Historically, the majority of cancer survivorship studies were from the United States, but survivorship issues are increasingly being addressed in other developed countries. Cross-cultural studies remain, however, scarce. The degree to which knowledge attained may or may not be transferred across cultures, countries, or regions is not known. Some important challenges for comparative research are therefore discussed in a cross-cultural perspective. Several substantive and methodological challenges that complicate the execution of cross-cultural cancer survivorship research are presented with examples and discussed to facilitate comparative research efforts in the establishment of new survivorship cohorts and in the planning and implementation of survivorship studies. Comparative research is one key to understanding the nature of cancer survivorship, distinguishing modifiable from nonmodifiable factors at individual, hospital, societal, and system levels and may thus guide appropriate interventions. Lastly, suggested future courses of action within the field of comparative cancer survivorship research are provided.

  6. [Cancer treatment in elderly patients: evidence and clinical research]. (United States)

    Repetto, Lazzaro; Luciani, Andrea


    showed a good sensibility (87.3%) but a low specificity (62%) with respect to CGA for the diagnosis of patients with disabilities. Overcash et al. proposed an abbreviated form of CGA using a reduced number of items of ADL, IADL, MMSE and GDS. There was a good correlation between complete and reduced scales (coefficient of correlation 0.8). G8 is a screening tool composed of 8 questions that explore functional, cognitive and nutritional status. The score with the best equilibrium between sensibility and specificity was 14 (sensibility 85% and specificity 65%). In the first observational trial age, hystotype, chemotherapy dose, haemoglobin (man: 11 g/dL; women: 10 g/dL), creatinine clearance less than 34 mL/min (Jelliffe formula), earing problems, at least a fall in the last six months, walking problems, low social activity, were related to a major risk of toxicity; in another trial IADL, diastolic blood pressure, LDH and MAX2 index were predictive of haematological toxicity, while performance status, Mini-Mental Status score, Mini-Nutritional Assessment (MNA) score and MAX2 index were predictive of non haematological toxicity. Based on these parameters a 0-2 score was developed. A recent "position article" of EORTC (European organization for Research and Treatment of Cancer) and SIOG analyzed the pro and the contra of the use of some indicators in elderly patients. The overall survival (OS) frequently used in classical clinical trial could give wrong messages as there are some competitive risks of death in elderly patients. Another important indicator is the disease specific survival (DSS). Concerning the design of clinical trials, a possible strategy is to enrol elderly patients without upper age limit and to plan stratification. An interesting trial design is the so called "extended trial" that allow to re-open the arm of a trial in which a too low number of older patients was enrolled.

  7. Eurocan plus report: feasibility study for coordination of national cancer research activities. (United States)


    The EUROCAN+PLUS Project, called for by the European Parliament, was launched in October 2005 as a feasibility study for coordination of national cancer research activities in Europe. Over the course of the next two years, the Project process organized over 60 large meetings and countless smaller meetings that gathered in total over a thousand people, the largest Europe-wide consultation ever conducted in the field of cancer research.Despite a strong tradition in biomedical science in Europe, fragmentation and lack of sustainability remain formidable challenges for implementing innovative cancer research and cancer care improvement. There is an enormous duplication of research effort in the Member States, which wastes time, wastes money and severely limits the total intellectual concentration on the wide cancer problem. There is a striking lack of communication between some of the biggest actors on the European scene, and there are palpable tensions between funders and those researchers seeking funds.It is essential to include the patients' voice in the establishment of priority areas in cancer research at the present time. The necessity to have dialogue between funders and scientists to establish the best mechanisms to meet the needs of the entire community is evident. A top priority should be the development of translational research (in its widest form), leading to the development of effective and innovative cancer treatments and preventive strategies. Translational research ranges from bench-to-bedside innovative cancer therapies and extends to include bringing about changes in population behaviours when a risk factor is established.The EUROCAN+PLUS Project recommends the creation of a small, permanent and independent European Cancer Initiative (ECI). This should be a model structure and was widely supported at both General Assemblies of the project. The ECI should assume responsibility for stimulating innovative cancer research and facilitating processes

  8. Research from the Early Detection Research Network on New Methods to Detect Prostate Cancer | Division of Cancer Prevention (United States)

    Prostate cancer is the most frequently diagnosed non-skin cancer in men in the United States. In 2010 there were 218,000 men diagnosed with prostate cancer. The prevalence of the diagnosis makes the disease a major health burden. While the majority of the diagnosed men will survive the disease, about 15% will die from it, a rate that is affected by over-diagnosis and the consequent over-treatment. |

  9. Native Speakers' Perception of Non-Native English Speech (United States)

    Jaber, Maysa; Hussein, Riyad F.


    This study is aimed at investigating the rating and intelligibility of different non-native varieties of English, namely French English, Japanese English and Jordanian English by native English speakers and their attitudes towards these foreign accents. To achieve the goals of this study, the researchers used a web-based questionnaire which…

  10. Short-term outcomes of the prospective multicentre 'Prostate Cancer Research International : Active Surveillance' study

    NARCIS (Netherlands)

    van den Bergh, Roderick C. N.; Vasarainen, Hanna; van der Poel, Henk G.; Vis-Maters, Jenneke J.; Rietbergen, John B.; Pickles, Tom; Cornel, Erik B.; Valdagni, Riccardo; Jaspars, Joris J.; van der Hoeven, John; Staerman, Frederic; Oomens, Eric H. G. M.; Rannikko, Antti; Roemeling, Stijn; Steyerberg, Ewout W.; Roobol, Monique J.; Schroder, Fritz H.; Bangma, Chris H.


    OBJECTIVE To evaluate the short-term outcomes of the prospective international Prostate Cancer Research International: Active Surveillance ('PRIAS') study (Dutch Trial Register NTR1718), as active surveillance (AS) for early prostate cancer might provide a partial solution to the current overtreatme

  11. Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention (United States)

    In response to a series of controversial articles about nutritional epidemiology and cancer published in 2014, staff from the Environmental Epidemiology Branch initiated a series of meetings to refine programmatic priorities for human nutrition/physical activity and cancer etiology research in the near term.

  12. New Funding Opportunity: Biospecimen Core Resource - Office of Cancer Clinical Proteomics Research (United States)

    The purpose of this notice is to notify the community that the National Cancer Institute's (NCI’s) Office of Cancer Clinical Proteomics Research (OCCPR) is seeking sources to establish a Biospecimen Core Resource (BCR), capable of receiving, qualifying, processing, and distributing annotated biospecimens.

  13. Research data supporting "Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer"



    Complete data set for the manuscript "Crowdsourcing the general public for large scale molecular pathology studies in cancer". Published at: This work was supported by the Cancer Research UK [C490/A10124, C490/A16561

  14. New Funding Opportunity: Tissue Purchase Order Acquisitions - Office of Cancer Clinical Proteomics Research (United States)

    The National Cancer Institute (NCI) is expanding its basic and translational research programs that rely heavily on sufficient availability of high quality, well annotated biospecimens suitable for use in genomic and proteomic studies. The NCI’s overarching goal with such programs is to improve the ability to diagnose, treat, and prevent cancer.

  15. Leininger's Ethnonursing Research Methodology and Studies of Cancer Survivors: A Review. (United States)

    Farren, Arlene T


    The purpose of this article is to present the findings of a literature review regarding the use of Leininger's ethnonursing research methodology (ENRM) in studies addressing adult cancer survivors. It is important to learn about differences and similarities among cancer survivors' experiences so that patient-centered, culturally congruent care can be provided. A review of the literature was conducted using databases such as CINAHL and MEDLINE. Search terms included variations on ENRM and cancer survivors. The results were a small number of published studies that used the ENRM examining breast cancer survivors' perceptions and experiences. A review instrument was developed to estimate study quality based on established criteria. The studies are critiqued in relation to the theory-based methodology, evaluation criteria for qualitative research, and study findings are summarized. The author concludes that although there is a paucity of research using ENRM with adult cancer survivors, the preliminary findings of the included studies contribute to what is known about breast cancer survivors. Implications for research include recommendations to increase the use of ENRM to discover the universal and diverse experiences of care practices in adult cancer survivors and use the evidence to develop patient-centered, culturally congruent, quality care for cancer survivors.

  16. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer


    Eccles, Suzanne A.; Aboagye, Eric O; Ali, Simak; Anderson, Annie S; Armes, Jo; Berditchevski, Fedor; Blaydes, Jeremy P.; Brennan, Keith; Brown, Nicola J; Bryant, Helen E; Bundred, Nigel J; Burchell, Joy M; Campbell, Anna M; Carroll, Jason S.; Clarke, Robert


    Introduction: Breast cancer remains a significant scientific, clinical and societal challenge. This gap analysis has reviewed and critically assessed enduring issues and new challenges emerging from recent research, and proposes strategies for translating solutions into practice.Methods: More than 100 internationally recognised specialist breast cancer scientists, clinicians and healthcare professionals collaborated to address nine thematic areas: genetics, epigenetics and epidemiology; molec...

  17. Critical Appraisal of Translational Research Models for Suitability in Performance Assessment of Cancer Centers


    Rajan, Abinaya; Sullivan, Richard; Bakker, Suzanne; van Harten, Wim H.


    This study aimed to critically appraise translational research models for suitability in performance assessment of cancer centers. Process models, such as the Process Marker Model and Lean and Six Sigma applications, seem to be suitable for performance assessment of cancer centers. However, they must be thoroughly tested in practice.

  18. Cancer, Employment, and American Indians: A Participatory Action Research Pilot Study (United States)

    Johnson, Sharon R.; Finifrock, DeAnna; Marshall, Catherine A.; Jaakola, Julia; Setterquist, Janette; Burross, Heidi L.; Hodge, Felicia Schanche


    American Indian cancer survivors are an underserved and understudied group. In this pilot study we attempted to address, through participatory action research, missing information about those factors that serve to either facilitate employment or hinder it for adult cancer survivors. One task of the study was to develop and/or modify…

  19. Approaches to Art Therapy for Cancer Inpatients: Research and Practice Considerations (United States)

    Nainis, Nancy A.


    Common symptoms reported by cancer patients include pain, fatigue, breathlessness, insomnia, lack of appetite, and anxiety. A study conducted by an interdisciplinary research team (Nainis et al., 2006) demonstrated statistically significant reductions in these cancer symptoms with the use of traditional art therapy methods. The study found a…

  20. Caring for caregivers and patients: Research and clinical priorities for informal cancer caregiving. (United States)

    Kent, Erin E; Rowland, Julia H; Northouse, Laurel; Litzelman, Kristin; Chou, Wen-Ying Sylvia; Shelburne, Nonniekaye; Timura, Catherine; O'Mara, Ann; Huss, Karen


    Informal/family caregivers are a fundamental source of care for cancer patients in the United States, yet the population of caregivers and their tasks, psychosocial needs, and health outcomes are not well understood. Changes in the nature of cancer care and its delivery, along with the growing population of survivors and their caregivers, warrant increased attention to the roles and demands of caregiving. This article reviews current evidence presented at a 2-day meeting examining the state of the science of informal cancer caregiving that was convened by the National Cancer Institute and the National Institute of Nursing Research. The meeting sought to define who is an informal cancer caregiver, summarize the state of the science in informal cancer caregiving, and describe both the kinds of interventions developed to address caregiving challenges and the various outcomes used to evaluate their impact. This article offers recommendations for moving science forward in 4 areas: 1) improving the estimation of the prevalence and burden of informal cancer caregiving; 2) advancing the development of interventions designed to improve outcomes for cancer patients, caregivers, and patient-caregiver dyads; 3) generating and testing strategies for integrating caregivers into formal health care settings; and 4) promoting the use of technology to support informal cancer caregivers. Cancer 2016;122:1987-95. © 2016 American Cancer Society.