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Sample records for cancer fallopian tube

  1. Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer

    Science.gov (United States)

    2016-02-09

    Stage I Ovarian Cancer; Stage IA Fallopian Tube Cancer; Stage IB Fallopian Tube Cancer; Stage IC Fallopian Tube Cancer; Stage II Ovarian Cancer; Stage IIA Fallopian Tube Cancer; Stage IIB Fallopian Tube Cancer; Stage IIC Fallopian Tube Cancer; Stage III Ovarian Cancer; Stage III Primary Peritoneal Cancer; Stage IIIA Fallopian Tube Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIC Fallopian Tube Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Primary Peritoneal Cancer

  2. Paraneoplastic Neurological Syndrome in Fallopian Tube Cancer.

    Science.gov (United States)

    Maas, E; Skoberne, T; Werner, A; Braun, S; Jackisch, C

    2014-10-01

    We report on a rare case of paraneoplastic syndrome (PS) that was discovered on completion of diagnostic work-up to be an undifferentiated fallopian tube carcinoma. A 49-year-old Caucasian woman was admitted to neurology with vertigo, gait ataxia and dysarthria, transient ischaemic attack (TIA) and stroke were quickly excluded. Indicative for the further diagnosis of a paraneoplastic syndrome was the identification of onconeuronal antibodies the detection of which can be associated with certain tumour entities. The strongly positive anti-Yo antibody that is formed above all by breast and lung cancers as well as ovarian cancer led to a corresponding staging. The tumour markers CEA, CA 125 and CA 15-3 were in the normal ranges. Mammography and thorax CT were also unremarkable; on transvaginal sonography the internal genitals were inconspicuous except for a follicular cyst on the left. On abdominal CT the only conspicuous finding was a 1.5 cm ovarian cyst. After consensual agreement a bilateral laparoscopic adenexectomy was performed but with unremarkable abdominal findings. The histological examination confirmed a right-sided undifferentiated tubal carcinoma with the provisional classification FIGO IIA. After a stage-related staging operation, the final classification was found to be the FIGO-IIIC stage on account of positive retroperitoneal lymph nodes. Thus adjuvant chemotherapy with 6 cycles of carboplatin and paclitaxel was performed. By means of a timely, guideline-conform therapy for tubal carcinoma, the neurological symptoms and, above all, the dysarthria could be improved after 10 months.

  3. Serous ovarian, fallopian tube and primary peritoneal cancers

    DEFF Research Database (Denmark)

    Sørensen, Rie D; Schnack, Tine H; Karlsen, Mona A;

    2015-01-01

    OBJECTIVE: The aim of this systematic review is to analyze data on risk factors, epidemiology, clinicopathology and molecular biology from studies comparing primary peritoneal cancer, fallopian tube cancer and ovarian cancer of serous histology, in order to achieve a greater understanding...... of whether or not these disorders should be considered as separate entities. METHODS: A systematic literature search was conducted in PubMed and MEDLINE. Case-control studies comparing primary serous peritoneal or fallopian tube carcinomas with primary serous ovarian carcinomas or a control group were...... included. RESULTS: Twenty-eight studies were found eligible. Primary peritoneal cancer patients were older, had higher parity, were more often obese and had poorer survival compared to ovarian cancer patients. Differences in protein expression patterns of Her2/neu, estrogen and progestin receptors...

  4. Paclitaxel, Polyglutamate Paclitaxel, or Observation in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Peritoneal Cancer, or Fallopian Tube Cancer

    Science.gov (United States)

    2016-03-17

    Fallopian Tube Clear Cell Adenocarcinoma; Fallopian Tube Endometrioid Adenocarcinoma; Fallopian Tube Mucinous Adenocarcinoma; Fallopian Tube Serous Adenocarcinoma; Fallopian Tube Transitional Cell Carcinoma; Malignant Ovarian Mixed Epithelial Tumor; Ovarian Brenner Tumor; Ovarian Clear Cell Adenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Adenocarcinoma; Ovarian Serous Adenocarcinoma; Ovarian Transitional Cell Carcinoma; Primary Peritoneal Serous Adenocarcinoma; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Cancer; Stage IIIA Primary Peritoneal Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Cancer; Stage IIIB Primary Peritoneal Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Cancer; Stage IIIC Primary Peritoneal Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Primary Peritoneal Cancer; Undifferentiated Fallopian Tube Carcinoma; Undifferentiated Ovarian Carcinoma

  5. Pembrolizumab, Bevacizumab, and Cyclophosphamide in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

    Science.gov (United States)

    2016-07-29

    Fallopian Tube Clear Cell Adenocarcinoma; Fallopian Tube Endometrioid Adenocarcinoma; Fallopian Tube Mucinous Adenocarcinoma; Fallopian Tube Serous Adenocarcinoma; Ovarian Clear Cell Adenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Adenocarcinoma; Ovarian Serous Adenocarcinoma; Primary Peritoneal Serous Adenocarcinoma; Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Undifferentiated Fallopian Tube Carcinoma; Undifferentiated Ovarian Carcinoma

  6. Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening

    Science.gov (United States)

    ... cells form in the ovaries, fallopian tubes, or peritoneum. The ovaries are a pair of organs in ... the ovary and spreads to the ovary. The peritoneum is the tissue that lines the abdominal wall ...

  7. Risks of Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening

    Science.gov (United States)

    ... cells form in the ovaries, fallopian tubes, or peritoneum. The ovaries are a pair of organs in ... the ovary and spreads to the ovary. The peritoneum is the tissue that lines the abdominal wall ...

  8. General Information About Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

    Science.gov (United States)

    ... cells form in the ovaries, fallopian tubes, or peritoneum. The ovaries are a pair of organs in ... the ovary and spreads to the ovary. The peritoneum is the tissue that lines the abdominal wall ...

  9. Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Prevention

    Science.gov (United States)

    ... cells form in the ovaries, fallopian tubes, or peritoneum. The ovaries are a pair of organs in ... the ovary and spreads to the ovary. The peritoneum is the tissue that lines the abdominal wall ...

  10. Vaccine Therapy and Cyclophosphamide in Treating Patients With Stage II-III Breast or Stage II-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

    Science.gov (United States)

    2016-01-07

    Recurrent Breast Carcinoma; Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Stage IIA Breast Cancer; Stage IIA Fallopian Tube Cancer; Stage IIA Ovarian Cancer; Stage IIB Breast Cancer; Stage IIB Fallopian Tube Cancer; Stage IIB Ovarian Cancer; Stage IIC Fallopian Tube Cancer; Stage IIC Ovarian Cancer; Stage IIIA Breast Cancer; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Cancer; Stage IIIA Primary Peritoneal Cancer; Stage IIIB Breast Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Cancer; Stage IIIB Primary Peritoneal Cancer; Stage IIIC Breast Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Cancer; Stage IIIC Primary Peritoneal Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Primary Peritoneal Cancer

  11. Morphologic 3D scanning of fallopian tubes to assist ovarian cancer diagnosis

    Science.gov (United States)

    Madore, Wendy-Julie; De Montigny, Etienne; Deschênes, Andréanne; Benboujja, Fouzi; Leduc, Mikael; Mes-Masson, Anne-Marie; Provencher, Diane M.; Rahimi, Kurosh; Boudoux, Caroline; Godbout, Nicolas

    2016-02-01

    Pathological evaluation of the fallopian tubes is an important diagnostic result but tumors can be missed using routine approaches. As the majority of high-grade serous ovarian cancers are now believed to originate in the fallopian tubes, pathological examination should include in a thorough examination of the excised ovaries and fallopian tubes. We present an dedicated imaging system for diagnostic exploration of human fallopian tubes. This system is based on optical coherence tomography (OCT), a laser imaging modality giving access to sub- epithelial tissue architecture. This system produces cross-sectional images up to 3 mm in depth, with a lateral resolution of ≍15μm and an axial resolution of ≍12μm. An endoscopic single fiber probe was developed to fit in a human fallopian tube. This 1.2 mm probe produces 3D volume data of the entire inner tube within a few minutes. To demonstrate the clinical potential of OCT for lesion identification, we studied 5 different ovarian lesions and healthy fallopian tubes. We imaged 52 paraffin-embedded human surgical specimens with a benchtop system and compared these images with histology slides. We also imaged and compared healthy oviducts from 3 animal models to find one resembling the human anatomy and to develop a functional ex vivo imaging procedure with the endoscopic probe. We also present an update on an ongoing clinical pilot study on women undergoing prophylactic or diagnostic surgery in which we image ex vivo fallopian tubes with the endoscopic probe.

  12. Metformin Hydrochloride and Combination Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

    Science.gov (United States)

    2016-05-18

    Brenner Tumor; Malignant Ascites; Malignant Pleural Effusion; Ovarian Clear Cell Cystadenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mixed Epithelial Carcinoma; Ovarian Serous Cystadenocarcinoma; Ovarian Undifferentiated Adenocarcinoma; Recurrent Fallopian Tube Cancer; Recurrent Ovarian Epithelial Cancer; Recurrent Ovarian Germ Cell Tumor; Recurrent Primary Peritoneal Cavity Cancer; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Epithelial Cancer; Stage IIIA Ovarian Germ Cell Tumor; Stage IIIA Primary Peritoneal Cavity Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Epithelial Cancer; Stage IIIB Ovarian Germ Cell Tumor; Stage IIIB Primary Peritoneal Cavity Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Epithelial Cancer; Stage IIIC Ovarian Germ Cell Tumor; Stage IIIC Primary Peritoneal Cavity Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Epithelial Cancer; Stage IV Ovarian Germ Cell Tumor; Stage IV Primary Peritoneal Cavity Cancer

  13. Activated T-cell Therapy, Low-Dose Aldesleukin, and Sargramostim in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer That is Stage III-IV, Refractory, or Recurrent

    Science.gov (United States)

    2016-02-15

    Malignant Ovarian Clear Cell Tumor; Malignant Ovarian Serous Tumor; Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Cancer; Stage IIIA Primary Peritoneal Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Cancer; Stage IIIB Primary Peritoneal Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Cancer; Stage IIIC Primary Peritoneal Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Primary Peritoneal Cancer

  14. Validation of epithelial ovarian cancer and fallopian tube cancer and ovarian borderline tumor data in the Danish Gynecological Cancer Database

    DEFF Research Database (Denmark)

    Petri, Anette Lykke; Kjaer, Susanne Krüger; Christensen, Ib J;

    2009-01-01

    OBJECTIVE: To validate the data on epithelial ovarian cancer, fallopian tube cancer and borderline ovarian tumors registered in the nationwide Danish Gynecological Cancer Database (DGCD) in 2005 and 2006. The DGCD is a multidisciplinary database that contains data for research and quality...... improvement. DESIGN: Comparative registry-based study supplemented with data from medical records. SETTING: Six hospitals in Denmark. PARTICIPANTS: Women registered with epithelial ovarian cancer, fallopian tube cancer and borderline ovarian tumor. MAIN OUTCOME MEASURE: Data completeness and strength of...... validity of ovarian cancer data in the DGCD is sufficient for quality monitoring in gynecological oncology....

  15. Validation of epithelial ovarian cancer and fallopian tube cancer and ovarian borderline tumor data in the Danish Gynecological Cancer Database

    DEFF Research Database (Denmark)

    Petri, A.L.; Kjaer, S.K.; Christensen, I.J.;

    2009-01-01

    OBJECTIVE: To validate the data on epithelial ovarian cancer, fallopian tube cancer and borderline ovarian tumors registered in the nationwide Danish Gynecological Cancer Database (DGCD) in 2005 and 2006. The DGCD is a multidisciplinary database that contains data for research and quality...... improvement. DESIGN: Comparative registry-based study supplemented with data from medical records. SETTING: Six hospitals in Denmark. PARTICIPANTS: Women registered with epithelial ovarian cancer, fallopian tube cancer and borderline ovarian tumor. MAIN OUTCOME MEASURE: Data completeness and strength of...... validity of ovarian cancer data in the DGCD is sufficient for quality monitoring in gynecological oncology Udgivelsesdato: 2009...

  16. Asymptomatic Primary Fallopian Tube Cancer: An Unusual Cause of Axillary Lymphadenopathy

    Directory of Open Access Journals (Sweden)

    N. A. Healy

    2011-01-01

    Full Text Available Primary Fallopian tube malignancy is considered a rare disease and is often mistaken histologically and clinically for ovarian cancer. The etiology is poorly understood, and it typically presents at an advanced disease stage, as symptoms are often absent in the initial period. As a result, primary fallopian tube cancer is generally associated with a poor prognosis. We present the case of a 45-year-old female who presents with a 5-day history of left axillary swelling and a normal breast examination. Mammogram and biopsy of a lesion in the left breast revealed a fibroadenoma but no other abnormalities. Initial sampling of the axillary node was suspicious for a primary breast malignancy, but histology of the excised node refuted this. PET-CT showed an area of high uptake in the right pelvis, and a laparoscopy identified a tumor of the left fallopian tube which was subsequently excised and confirmed as a serous adenocarcinoma.

  17. Changes in Brain Function in Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Are Receiving Chemotherapy

    Science.gov (United States)

    2016-02-09

    Cognitive Side Effects of Cancer Therapy; Malignant Ovarian Epithelial Tumor; Malignant Ovarian Mixed Epithelial Tumor; Ovarian Brenner Tumor; Ovarian Carcinosarcoma; Ovarian Choriocarcinoma; Ovarian Clear Cell Cystadenocarcinoma; Ovarian Dysgerminoma; Ovarian Embryonal Carcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mixed Germ Cell Tumor; Ovarian Mucinous Cystadenocarcinoma; Ovarian Polyembryoma; Ovarian Sarcoma; Ovarian Serous Cystadenocarcinoma; Ovarian Teratoma; Ovarian Yolk Sac Tumor; Stage I Ovarian Cancer; Stage IA Fallopian Tube Cancer; Stage IA Ovarian Cancer; Stage IA Ovarian Germ Cell Tumor; Stage IB Fallopian Tube Cancer; Stage IB Ovarian Cancer; Stage IB Ovarian Germ Cell Tumor; Stage IC Fallopian Tube Cancer; Stage IC Ovarian Cancer; Stage IC Ovarian Germ Cell Tumor; Stage II Ovarian Cancer; Stage IIA Fallopian Tube Cancer; Stage IIA Ovarian Cancer; Stage IIA Ovarian Germ Cell Tumor; Stage IIB Fallopian Tube Cancer; Stage IIB Ovarian Cancer; Stage IIB Ovarian Germ Cell Tumor; Stage IIC Fallopian Tube Cancer; Stage IIC Ovarian Cancer; Stage IIC Ovarian Germ Cell Tumor; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Cancer; Stage IIIA Ovarian Germ Cell Tumor; Stage IIIA Primary Peritoneal Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Cancer; Stage IIIB Ovarian Germ Cell Tumor; Stage IIIB Primary Peritoneal Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Cancer; Stage IIIC Ovarian Germ Cell Tumor; Stage IIIC Primary Peritoneal Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Ovarian Germ Cell Tumor; Stage IV Primary Peritoneal Cancer; Undifferentiated Ovarian Carcinoma

  18. Isolated Fallopian Tube Torsion

    Directory of Open Access Journals (Sweden)

    S. Kardakis

    2013-01-01

    Full Text Available Isolated torsion of the Fallopian tube is a rare gynecological cause of acute lower abdominal pain, and diagnosis is difficult. There are no pathognomonic symptoms; clinical, imaging, or laboratory findings. A preoperative ultrasound showing tubular adnexal masses of heterogeneous echogenicity with cystic component is often present. Diagnosis can rarely be made before operation, and laparoscopy is necessary to establish the diagnosis. Unfortunately, surgery often is performed too late for tube conservation. Isolated Fallopian tube torsion should be suspected in case of acute pelvic pain, and prompt intervention is necessary.

  19. Primary fallopian tube carcinoma

    Directory of Open Access Journals (Sweden)

    Mladenović-Segedi Ljiljana

    2009-01-01

    Full Text Available Introduction. Primary fallopian tube carcinoma is extremely rare, making 0.3-1.6% of all female genital tract malignancies. Although the etymology of this tumor is unknown, it is suggested to be associated with chronic tubal inflammation, infertility, tuberculous salpingitis and tubal endometriosis. High parity is considered to be protective. Cytogenetic studies show the disease to be associated with over expression of p53, HER2/neu and c-myb. There is also some evidence that BRCA1 and BRCA2 mutations have a role in umorogeneis. Clinical features. The most prevailing symptoms with fallopian tube carcinoma are abdominal pain, abnormal vaginal discharge/bleeding and the most common finding is an adnexal mass. In many patients, fallopian tube carcinoma is asymptomatic. Diagnosis. Due to its rarity, preoperative diagnosis of primary fallopian tube carcinoma is rarely made. It is usually misdiagnosed as ovarian carcinoma, tuboovarian abscess or ectopic pregnancy. Sonographic features of the tumor are non-specific and include the presence of a fluid-filled adnexal structure with a significant solid component, a sausage-shaped mass, a cystic mass with papillary projections within, a cystic mass with cog wheel appearance and an ovoid-shaped structure containing an incomplete separation and a highly vascular solid nodule. More than 80% of patients have elevated pretreatment serum CA-125 levels, which is useful in follow-up after the definite treatment. Treatment. The treatment approach is similar to that of ovarian carcinoma, and includes total abdominal hysterectomy and bilateral salpingo-oophorectomy. Staging is followed with chemotherapy.

  20. Multispectral fluorescence imaging of human ovarian and fallopian tube tissue for early-stage cancer detection

    Science.gov (United States)

    Tate, Tyler H.; Baggett, Brenda; Rice, Photini F. S.; Koevary, Jennifer Watson; Orsinger, Gabriel V.; Nymeyer, Ariel C.; Welge, Weston A.; Saboda, Kathylynn; Roe, Denise J.; Hatch, Kenneth D.; Chambers, Setsuko K.; Utzinger, Urs; Barton, Jennifer Kehlet

    2016-05-01

    With early detection, 5-year survival rates for ovarian cancer exceed 90%, yet no effective early screening method exists. Emerging consensus suggests over 50% of the most lethal form of the disease originates in the fallopian tube. Twenty-eight women undergoing oophorectomy or debulking surgery provided informed consent for the use of surgical discard tissue samples for multispectral fluorescence imaging. Using multiple ultraviolet and visible excitation wavelengths and emissions bands, 12 fluorescence and 6 reflectance images of 47 ovarian and 31 fallopian tube tissue samples were recorded. After imaging, each sample was fixed, sectioned, and stained for pathological evaluation. Univariate logistic regression showed cancerous tissue samples had significantly lower intensity than noncancerous tissue for 17 image types. The predictive power of multiple image types was evaluated using multivariate logistic regression (MLR) and quadratic discriminant analysis (QDA). Two MLR models each using two image types had receiver operating characteristic curves with area under the curve exceeding 0.9. QDA determined 56 image type combinations with perfect resubstituting using as few as five image types. Adaption of the system for future in vivo fallopian tube and ovary endoscopic imaging is possible, which may enable sensitive detection of ovarian cancer with no exogenous contrast agents.

  1. The Molecular Fingerprint of High Grade Serous Ovarian Cancer Reflects Its Fallopian Tube Origin

    Directory of Open Access Journals (Sweden)

    Thomas Meyer

    2013-03-01

    Full Text Available High grade serous ovarian cancer (HGSC, the most lethal and frequent type of epithelial ovarian cancer (EOC, has poor long term prognosis due to a combination of factors: late detection, great metastatic potential and the capacity to develop resistance to available therapeutic drugs. Furthermore, there has been considerable controversy concerning the etiology of this malignancy. New studies, both clinical and molecular, strongly suggest that HGSC originates not from the surface of the ovary, but from the epithelial layer of the neighboring fallopian tube fimbriae. In this paper we summarize data supporting the central role of fallopian tube epithelium in the development of HGSC. Specifically, we address cellular pathways and regulatory mechanisms which are modulated in the process of transformation, but also genetic changes which accumulate during disease progression. Similarities between fallopian tube mucosa and the malignant tissue of HGSC warrant a closer analysis of homeostatic mechanisms in healthy epithelium in order to elucidate key steps in disease development. Finally, we highlight the importance of the cancer stem cell (CSC identification and understanding of its niche regulation for improvement of therapeutic strategies.

  2. Case Report: Liquid-based cytology aids in primary fallopian tube cancer diagnosis

    Institute of Scientific and Technical Information of China (English)

    Zhuo REN; Yun-ping ZHANG; Hui-xia YANG; Li-rong ZHU

    2009-01-01

    Primary fallopian tube carcinoma (PFTC) is a rare malignant carcinoma among all genital tract malignancies. It occurs most commonly in postmenopausal women and is similar to ovarian malignancy historically and clinically. Because of its insidious onset and silent course, the diagnosis is made usually postoperatively. Liquid-based cytology (LBC) is a type of method for cervical cancer screening, but sometimes it may aid in making PFTC diagnosis. We report a 47-year-old woman with PFTC, whose diagnosis was made with the aid of LBC.

  3. Ovarian cancer: the Fallopian tube as the site of origin and opportunities for prevention

    Directory of Open Access Journals (Sweden)

    Sophia HL George, PhD

    2016-05-01

    Full Text Available High-grade serous carcinoma is the most common and aggressive histotype of epithelial ovarian cancer, and it is the predominant histotype associated with hereditary breast and ovarian cancer syndrome (HBOC. Mutations in BRCA1 and BRCA2 are responsible for most of the known causes of HBOC, while mutations in mismatch repair genes and several genes of moderate penetrance are responsible for the remaining known hereditary risk. Women with a history of familial ovarian cancer or with known germline mutations in highly penetrant genes are offered the option risk-reducing surgery, which involves the removal of the ovaries and fallopian tubes (salpingo-oophorectomy. Growing evidence now supports the fallopian tube epithelia as an etiological site for the development of HGSC and consequently, salpingectomy alone is emerging as a prophylactic option. This review discusses the site of origin of epithelial ovarian cancer, the rationale for risk-reducing salpingectomy in the high-risk population and opportunities for salpingectomy in the low-risk population.

  4. Drugs Approved for Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for ovarian cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  5. Duplication of the fallopian tube

    Directory of Open Access Journals (Sweden)

    R Narayanan

    2008-01-01

    Full Text Available Hysterosalpingography accurately delineates the uterine and tubal lumen, and hence is routinely performed for the evaluation of infertility.We observed a case of infertility where uterine cavity was normal but fallopian tubes were bifurcated at the ampullary region. Mullerian duct anomalies are reported in literature, but maldevelopment of fallopian tube in isolation is rare. This abnormality can present as infertility, ectopic pregnancy, in association with urinary tract anomalies or as failure of sterilisation method.

  6. Confocal microlaparoscope for imaging the fallopian tube

    Science.gov (United States)

    Wu, Tzu-Yu; Schafer, Rachel; Rouse, Andrew R.; Gmitro, Arthur F.

    2012-02-01

    Recent evidence suggests that epithelial ovarian cancer may originate in the fimbriated end of the fallopian tube1. Unlike many other cancers, poor access to the ovary and fallopian tubes has limited the ability to study the progression of this deadly disease and to diagnosis it during the early stage when it is most amenable to therapy. We have previously reported on a rigid confocal microlaparoscope system that is currently undergoing a clinical trial to image the epithelial surface of the ovary2. In order to gain in vivo access to the fallopian tubes we have developed a new confocal microlaparoscope with an articulating distal tip. The new instrument builds upon the technology developed for the existing confocal microlaparoscope. It has an ergonomic handle fabricated by a rapid prototyping printer. While maintaining compatibility with a 5 mm trocar, the articulating distal tip of the instrument consists of a 2.2 mm diameter bare fiber bundle catheter with automated dye delivery for fluorescence imaging. This small and flexible catheter design should enable the confocal microlaparoscope to image early stage ovarian cancer arising inside the fallopian tube. Early ex vivo mages of human fallopian tube and in vivo imaging results from recent open surgeries using the rigid confocal microlaparoscope system are presented. Ex vivo images from animal models using the new articulating bare fiber system are also presented. These high quality images collected by the new flexible system are similar in quality to those obtained from the epithelial surface of ovaries with the rigid clinical confocal microlaparoscope.

  7. Confocal microlaparoscope for imaging the fallopian tube

    Science.gov (United States)

    Wu, Tzu-Yu; Rouse, Andrew R.; Chambers, Setsuko K.; Hatch, Kenneth D.; Gmitro, Arthur F.

    2014-11-01

    Recent evidence suggests that ovarian cancer can originate in the fallopian tube. Unlike many other cancers, poor access to the ovary and fallopian tubes has limited the ability to study the progression of this deadly disease and to diagnosis it during the early stage when it is most amenable to therapy. A rigid confocal microlaparoscope system designed to image the epithelial surface of the ovary in vivo was previously reported. A new confocal microlaparoscope with an articulating distal tip has been developed to enable in vivo access to human fallopian tubes. The new microlaparoscope is compatible with 5-mm trocars and includes a 2.2-mm-diameter articulating distal tip consisting of a bare fiber bundle and an automated dye delivery system for fluorescence confocal imaging. This small articulating device should enable the confocal microlaparoscope to image early stage ovarian cancer arising inside the fallopian tube. Ex vivo images of animal tissue and human fallopian tube using the new articulating device are presented along with in vivo imaging results using the rigid confocal microlaparoscope system.

  8. [New FIGO classification of ovarian, fallopian tube and primary peritoneal cancer].

    Science.gov (United States)

    Höhn, A K; Einenkel, J; Wittekind, C; Horn, L-C

    2014-07-01

    During recent years paramount changes have occurred in the pathogenesis of ovarian cancer and recent clinical studies identified new prognostic factors. Consequently, the FIGO has established a new staging system collectively covering carcinomas derived from the ovaries, the fallopian tubes and primary peritoneal cancers as well as malignant ovarian germ cell and sex-cord stromal tumors. The new staging system started on 01 January 2014. Major changes occurred in the FIGO IC/T1c stage with surgical spill (FIGO IC1/T1c1) versus capsule ruptured before surgery or tumor on ovarian or fallopian tube surface (FIGO IC2/T1c2) versus malignant cells in the ascites or peritoneal washings (FIGO IC3/T1c3). The regional lymph node metastases were subcategorised using a cut-off value of 10 mm as the largest dimension of the metastatic deposits. Distant metastases (excluding peritoneal metastases) were substaged as FIGO IVA/M1a in cases of cytologically or histologically proven pleural involvement and as FIGO IVB/M1b in cases of parenchymal metastases and metastases in extra-abdominal organs (including lymph nodes outside the peritoneal cavity and the inguinal lymph nodes). PMID:24899496

  9. Capillary Hemangioma of the Fallopian Tube.

    Science.gov (United States)

    Katiyar, Richa; Patne, Shashikant C U; Bharti, Shreekant; Jain, Madhu

    2016-04-01

    Neoplastic lesions of the fallopian tube are rarely seen by surgical pathologists. Haemangioma of the fallopian tube is an extremely rare benign neoplasm. A 30-year-old lady with polymenorrhea and dysmenorrhea underwent hysterectomy and bilateral salpingo-oophorectomy. Her left fallopian tube showed a 2mm sized solid nodule in the wall. Histopathological examination revealed a well-defined vascular lesion in the left fallopian tube, consistent with capillary haemangioma. The vascular endothelium was highlighted by CD34 immunostaining. Our literature review has identified 10 cases of cavernous haemangioma of the fallopian tube. To the best of our knowledge, we report the first ever case of capillary haemangioma of the fallopian tube. This is also the smallest detected haemangioma in the fallopian tube. PMID:27190899

  10. The accessory fallopian tube: A rare anomaly

    Directory of Open Access Journals (Sweden)

    Kusum R Gandhi

    2012-01-01

    Full Text Available This paper presents a rare anatomical variation in the form of accessory fallopian tube on right side. The duplication of fallopian tube was observed in a 34-year-old female during routine undergraduate dissection in our department. Fallopian tube is the part of uterus that carries the ovum from the ovary to the uterus. Accessory fallopian tube is the congenital anomaly attached to the ampullary part of main tube. This accessory tube is common site of pyosalpinx, hydrosalpinx, cystic swelling and torsion. The ovum released by the ovary may also be captured by the blind accessory tube leading to infertility or ectopic pregnancy. Hence, all patients of infertility or pelvic inflammatory disease should be screened to rule out the presence of accessory fallopian tube and if encountered should be removed.

  11. Epothilones in epithelial ovarian, fallopian tube, or primary peritoneal cancer: a systematic review

    Directory of Open Access Journals (Sweden)

    Zagouri F

    2015-08-01

    Full Text Available Flora Zagouri,1 Theodoros N Sergentanis,2 Dimosthenis Chrysikos,2 Meletios-Athanassios Dimopoulos,1 Aristotle Bamias1 1Department of Clinical Therapeutics, Alexandra Hospital, 2First Propaedeutic Surgical Department, Hippokration Hospital, University of Athens, Athens, Greece Abstract: Ovarian cancer is the most lethal gynecologic malignancy; consequently, there is a need for effective therapies. Epothilones are microtubule-stabilizing agents that inhibit cell growth. Currently, patupilone and its four synthetic derivatives ixabepilone, BMS-310705, sagopilone, 20-desmethyl-20-methylsulfanyl epothilone B and epothilone D, as well as its derivative KOS-1584, are under clinical evaluation. This is the first systematic review conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines that synthesizes all available data emerging from trials and evaluates the efficacy and safety of epothilones in epithelial ovarian, primary fallopian tube, and primary peritoneal cancer. Despite the fact that epothilones have proven active in taxane-resistant settings in preclinical models, it is not yet clear from Phase II/III studies reviewed here that their clinical activity is superior to that of taxanes. Nevertheless, responses to epothilones have been observed in platinum-refractory/resistant ovarian cancer patients. Moreover, despite the shared mechanism of action of epothilones, their clinical profile seems clearly different, with diarrhea being the most common dose-limiting toxicity encountered with patupilone, whereas neutropenia and sensory neuropathy are the most common toxic effects observed with the other epothilones. In any case, randomized trials comparing epothilones with standard treatments seem warranted to define further the role of these agents, whereas biomarker analysis might further optimize patient selection. Keywords: ovarian cancer, epothilone, patupilone, ixabepilone, systematic

  12. Sargramostim and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer That Did Not Respond to Previous Chemotherapy

    Science.gov (United States)

    2014-01-15

    Brenner Tumor; Fallopian Tube Cancer; Ovarian Clear Cell Cystadenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mixed Epithelial Carcinoma; Ovarian Mucinous Cystadenocarcinoma; Ovarian Serous Cystadenocarcinoma; Ovarian Undifferentiated Adenocarcinoma; Peritoneal Cavity Cancer; Recurrent Ovarian Epithelial Cancer; Stage III Ovarian Epithelial Cancer; Stage IV Ovarian Epithelial Cancer

  13. Japan Society of Gynecologic Oncology guidelines 2015 for the treatment of ovarian cancer including primary peritoneal cancer and fallopian tube cancer.

    Science.gov (United States)

    Komiyama, Shinichi; Katabuchi, Hidetaka; Mikami, Mikio; Nagase, Satoru; Okamoto, Aikou; Ito, Kiyoshi; Morishige, Kenichiro; Suzuki, Nao; Kaneuchi, Masanori; Yaegashi, Nobuo; Udagawa, Yasuhiro; Yoshikawa, Hiroyuki

    2016-06-01

    The fourth edition of the Japan Society of Gynecologic Oncology guidelines for the treatment of ovarian cancer including primary peritoneal cancer and fallopian tube cancer was published in 2015. The guidelines contain seven chapters and six flow charts. The major changes in this new edition are as follows-(1) the format has been changed from reviews to clinical questions (CQ), and the guidelines for optimal clinical practice in Japan are now shown as 41 CQs and answers; (2) the 'flow charts' have been improved and placed near the beginning of the guidelines; (3) the 'basic points', including tumor staging, histological classification, surgical procedures, chemotherapy, and palliative care, are described before the chapter; (4) the FIGO surgical staging of ovarian cancer, fallopian tube cancer, and primary peritoneal cancer was revised in 2014 and the guideline has been revised accordingly to take the updated version of this classification into account; (5) the procedures for examination and management of hereditary breast and ovarian cancer are described; (6) information on molecular targeting therapy has been added; (7) guidelines for the treatment of recurrent cancer based on tumor markers alone are described, as well as guidelines for providing hormone replacement therapy after treatment. PMID:27142770

  14. 21 CFR 884.3650 - Fallopian tube prosthesis.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Fallopian tube prosthesis. 884.3650 Section 884.3650 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... § 884.3650 Fallopian tube prosthesis. (a) Identification. A fallopian tube prosthesis is a...

  15. Primary carcinoma of the Fallopian tubes

    International Nuclear Information System (INIS)

    The clinical case of a 53 year old patient with history of vaginal bleeding for possible uterine fibroma is described. A total hysterectomy with double ooferectomia was performed. The complementary tests results, including the biopsy, confirmed the presence of a primary carcinoma of the right Fallopian tube. A radiotherapy and follow up were indicated in 'Conrado Benitez' Oncology Hospital from Santiago de Cuba

  16. Carboplatin and Paclitaxel With or Without Bevacizumab Compared to Docetaxel, Carboplatin, and Paclitaxel in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Carcinoma (Cancer)

    Science.gov (United States)

    2013-03-18

    Brenner Tumor; Fallopian Tube Cancer; Ovarian Carcinosarcoma; Ovarian Clear Cell Cystadenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mixed Epithelial Carcinoma; Ovarian Mucinous Cystadenocarcinoma; Ovarian Serous Cystadenocarcinoma; Ovarian Undifferentiated Adenocarcinoma; Primary Peritoneal Cavity Cancer; Stage II Ovarian Epithelial Cancer; Stage III Ovarian Epithelial Cancer; Stage IV Ovarian Epithelial Cancer

  17. Paclitaxel, Bevacizumab And Adjuvant Intraperitoneal Carboplatin in Treating Patients Who Had Initial Debulking Surgery for Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

    Science.gov (United States)

    2014-06-18

    Brenner Tumor; Fallopian Tube Cancer; Ovarian Clear Cell Cystadenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mixed Epithelial Carcinoma; Ovarian Mucinous Cystadenocarcinoma; Ovarian Serous Cystadenocarcinoma; Ovarian Undifferentiated Adenocarcinoma; Primary Peritoneal Cavity Cancer; Stage II Ovarian Epithelial Cancer; Stage III Ovarian Epithelial Cancer; Stage IV Ovarian Epithelial Cancer

  18. Gemcitabine Hydrochloride With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

    Science.gov (United States)

    2016-09-19

    Ovarian Brenner Tumor; Ovarian Carcinosarcoma; Ovarian Clear Cell Cystadenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Cystadenocarcinoma; Ovarian Seromucinous Carcinoma; Ovarian Serous Cystadenocarcinoma; Ovarian Serous Surface Papillary Adenocarcinoma; Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Undifferentiated Ovarian Carcinoma

  19. Selective salpingography and recanalisation of blocked fallopian tubes.

    LENUS (Irish Health Repository)

    Allen, C

    2010-09-01

    Fallopian tubal disease is a common cause of subfertility. Reproductive surgery or assisted reproduction techniques such as in vitro fertilization (IVF) have been the main treatment options for patients with tubal disease in Ireland, although access to these treatments remains limited. We describe a case of pregnancy following selective salpingography and fallopian tube recanalisation.

  20. File list: ALL.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 All antigens Uterus Fallopian tube secret...hg19/assembled/ALL.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  1. File list: ALL.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 All antigens Uterus Fallopian tube secret...hg19/assembled/ALL.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  2. File list: ALL.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 All antigens Uterus Fallopian tube secret...hg19/assembled/ALL.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  3. Serous tubal intraepithelial carcinoma, chronic fallopian tube injury, and serous carcinoma development.

    Science.gov (United States)

    Malmberg, Karin; Klynning, Charlotta; Flöter-Rådestad, Angelique; Carlson, Joseph W

    2016-06-01

    Ovarian carcinoma is the deadliest gynecological malignancy. Previous studies have suggested that the fallopian tube may be the primary site for high-grade serous carcinoma. In prophylactic salpingo-oophorectomies from women with hereditary high risk for ovarian cancer, precursors can be assessed prior to onset and studied as a model for serous cancer precursor lesions. Epidemiologic studies indicate that carcinogenesis may be a result of chronic fallopian tube injury. The aims of this study were to (1) to examine the incidence of serous tubal intraepithelial carcinoma (STIC) in relation to other clinical parameters and (2) to evaluate whether chronic fallopian tube injury was related to cancer development. This study enrolled 101 women, comprising the following three groups: hereditary (n = 60), sporadic serous cancer (n = 18; endometrial cancers were excluded), and control (n = 23). The cases were histologically examined and clinical risk factors were collected. The histological changes were compared between different patients and correlated to clinical risk factors. STICs were identified primarily on the fallopian tube fimbria. The incidence of STIC was 3 % in the hereditary patients. In sporadic serous cancer cases, 61 % were associated with STIC and tubal carcinoma (p cancer group and the control group or within the hereditary group. STIC and invasive cancer were seen more often in the older patients than in the younger patients (p = 0.528). This small study, no correlation with chronic tubal injury or inflammation was identified. PMID:27003156

  4. Fallopian tube prolapse after hysterectomy: a systematic review.

    Directory of Open Access Journals (Sweden)

    Lobna Ouldamer

    Full Text Available BACKGROUND: Prolapse of the fallopian tube into the vaginal vault is a rarely reported complication that may occur after hysterectomy. Clinicians can miss the diagnosis of this disregarded complication when dealing with post-hysterectomy vaginal bleeding. OBJECTIVES: We performed a systematic review in order to describe the clinical presentation, therapeutic management and outcome of fallopian tube prolapse occurring after hysterectomy. SEARCH STRATEGY: A systematic search of MEDLINE and EMBASE references from January 1980 to December 2010 was performed. We included articles that reported cases of fallopian tube prolapse after hysterectomy. Data from eligible studies were independently extracted onto standardized forms by two reviewers. RESULTS: Twenty-eight articles including 51 cases of fallopian tube prolapse after hysterectomy were included in this systematic review. Clinical presentations included abdominal pain, dyspareunia, post- coital bleeding, and/or vaginal discharge. Two cases were asymptomatic and diagnosed at routine checkup. The surgical management reported comprised partial or total salpingectomy, with vaginal repair in some cases combined with oophorectomy using different approaches (vaginal approach, combined vaginal-laparoscopic approach, laparoscopic approach, or laparotomy. Six patients were initially treated by silver nitrate application without success. CONCLUSIONS: This systematic review provided a precise summary of the clinical characteristics and treatment of patients presenting with fallopian tube prolapse following hysterectomy published in the past 30 years. We anticipate that these results will help inform current investigations and treatment.

  5. A multicenter, non-randomized, phase II study of docetaxel and carboplatin administered every 3 weeks as second line chemotherapy in patients with first relapse of platinum sensitive epithelial ovarian, peritoneal or fallopian tube cancer

    DEFF Research Database (Denmark)

    Wang, Yun; Herrstedt, Jørn; Havsteen, Hanne;

    2014-01-01

    of 398 cycles were given. Grade 3/4 neutropenia was seen in 80% (59 of 74) patients with an incidence of febrile neutropenia of 16%. Grade 2/3 sensory peripheral neuropathy occurred in 7% of patients, but no grade 4 sensory peripheral neuropathy was observed. Sixty patients were evaluable for response...... of platinum-sensitive ovarian, peritoneal and Fallopian tube cancer. The major toxicity was neutropenia, while the frequency of peripheral neuropathy was low....

  6. Intrauterine insemination versus fallopian tube sperm perfusion for non-tubal infertility

    NARCIS (Netherlands)

    Cantineau, Astrid E. P.; Cohlen, Ben J.; Heineman, Maas Jan; Marjoribanks, Jane; Farquhar, Cindy

    2013-01-01

    Background Intrauterine insemination (IUI) is a common treatment for couples with subfertility that does not involve the fallopian tubes. It is used to bring the sperm close to the released oocyte. Another method of introducing sperm is fallopian tube sperm perfusion (FSP). Fallopian tube sperm perf

  7. [Isolated torsion of the fallopian tube: about two cases].

    Science.gov (United States)

    Bouguern, H; Bouchikhi, C; Chaara, H; Melhouf, M A; Banani, A

    2008-02-01

    Isolated torsion of the fallopian tube is extremely rare and difficult to diagnose, requires a coelioscopy, or a laparotomy in centers which do not have coelioscpie; often carried out too tardily, to allow the conservation of the horn. We report two observations of isolated torsion of the fallopian tube and we recall through the two clinical cases the diagnostic difficulties, the useful complementary examinations, the treatment and the causes of this pathology which must be systematically evoked in front of any acute abdominal syndrome in order to hope for an early surgical treatment and if possible conservative. PMID:18372548

  8. Cysticercosis of the fallopian tube: histology and microanalysis

    Energy Technology Data Exchange (ETDEWEB)

    Abraham, J.L.; Spore, W.W.; Benirschke, K.

    1982-07-01

    The authors identified a degenerated, focally calcified cestode larva (cysticercus) in the fallopian tube of a 50-year-old woman with endometriosis. The physiologic reaction to the larva was minimal, with some focal granulomatous salpingitis. No other focus of infection was detected. The differential diagnosis included trophoblastic tissue, foreign material, and parasites. Scanning electron microscopy and x-ray microanalysis of the organism revealed concentration of iodine in the subcuticular connective tissue of the larva and confirmed the calcium phosphate composition of the calcareous corpuscles. The presumed source of the iodine was the continued exposure of the larva to an environment rich in iodide secreted by the epithelium of the fallopian tube.

  9. A case of bilateral primary fallopian tube carcinoma

    Directory of Open Access Journals (Sweden)

    Manisha Sahu

    2014-09-01

    Full Text Available A 60 years old postmenopausal woman was presented with complaints of intermittent watery discharge from vagina, and of cramping pain at the lower abdomen. On pelvic examination, blood tinged watery discharge was seen coming out of os. But, ultrasonography revealed bilateral adenexal masses and pyometra. The serum CA-125 level in blood was raised. Cervical smear showed inflammatory changes, but endometrial histopathology was negative for malignant cells. Suspecting ovarian malignancy, laparotomy was done that revealed the bilateral tubal growth with normal ovaries; the right adenexal mass was of the size (6.8×4.8 cm while, the left adenexal mass was the size of (4.2×2.6 cm. Histopathology study revealed bilateral serous cyst adenocarcinoma of fallopian tubes. The case of bilateral primary fallopian tube carcinoma was presented here for its rarity.

  10. Intra-uterine insemination versus fallopian tube sperm perfusion for non-tubal infertility

    NARCIS (Netherlands)

    A.E.P. Cantineau; B.J. Cohlen; M.J. Heineman

    2009-01-01

    Background Controlled ovarian hyperstimulation (COH) combined with intrauterine insemination (IUI) is commonly offered to couples with subfertility that does not involve the fallopian tubes. Another method is fallopian tube sperm perfusion (FSP). This technique ensures the presence of higher sperm d

  11. File list: Unc.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 Unclassified Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Unc.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  12. File list: NoD.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 No description Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  13. File list: His.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 Histone Uterus Fallopian tube secret...2688,SRX1002689 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  14. File list: Oth.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 TFs and others Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  15. File list: Pol.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 RNA polymerase Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Pol.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  16. File list: DNS.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 DNase-seq Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  17. File list: Pol.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 RNA polymerase Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Pol.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  18. File list: His.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 Histone Uterus Fallopian tube secret...2680,SRX1002681 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  19. File list: Oth.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 TFs and others Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  20. File list: InP.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 Input control Uterus Fallopian tube secret...iencedbc.jp/kyushu-u/hg19/assembled/InP.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  1. File list: His.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 Histone Uterus Fallopian tube secret...2681,SRX1002688 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  2. File list: His.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  3. File list: DNS.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 DNase-seq Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  4. File list: NoD.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 No description Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  5. File list: DNS.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 DNase-seq Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  6. File list: Unc.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 Unclassified Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Unc.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  7. File list: Unc.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 Unclassified Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Unc.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  8. File list: Oth.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 TFs and others Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  9. File list: InP.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 Input control Uterus Fallopian tube secret...iencedbc.jp/kyushu-u/hg19/assembled/InP.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  10. File list: Pol.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 RNA polymerase Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Pol.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  11. File list: InP.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  12. File list: Oth.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 TFs and others Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  13. File list: InP.Utr.05.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  14. File list: NoD.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 No description Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  15. File list: DNS.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 DNase-seq Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.Utr.20.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  16. File list: NoD.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 No description Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.Utr.50.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  17. File list: Unc.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell hg19 Unclassified Uterus Fallopian tube secret...ory epithelial cell http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Unc.Utr.10.AllAg.Fallopian_tube_secretory_epithelial_cell.bed ...

  18. Bilateral primary fallopian tube papillary serous carcinoma in postmenopausal woman: Report of two cases

    Directory of Open Access Journals (Sweden)

    Dipanwita Nag

    2016-01-01

    Full Text Available Primary carcinoma of the fallopian tube is rare and accounts for about 0.14-1.8% of all gynecological malignancies. Correct diagnosis is rarely made preoperatively as clinically tubal carcinoma closely resembles ovarian carcinoma. Here, we report two cases of bilateral primary fallopian tube carcinomas. Case 1: A 54-year-old female presented with postmenopausal bleeding, abdominal pain, and pervaginal watery discharge for 10 days. Ultrasonography (USG of pelvis showed endometrial thickening and multiple tiny echogenic foci in omentum suggestive of omental cake. With a provisional diagnosis of endometrial carcinoma, total abdominal hysterectomy with bilateral salpingo-oophorectomy and omentectomy was done. On gross examination, small and rudimentary right ovary was adherent to the fimbrial end of the tube. Left-sided tubo-ovarian mass was present, cut section of which showed yellowish solid area in tubal wall and encroaching on ovarian surface. On histological examination, sections from the fimbrial end of both fallopian tubes showed features of papillary serous adenocarcinoma. Case 2: 70-year-old lady, 15 years postmenopausal presented with gradual onset pain and swelling of abdomen, urinary incontinence since 4 days. USG showed bulky uterus, 5 cm × 2 cm fibroid, bilateral tubes, and ovaries were not visualized. Serum cancer antigen-125 was raised (159.7 U/ml. Total hysterectomy and bilateral salpingo-oophorectomy with infracolic omentectomy was done. On gross examination, ovaries were firmly attached to tubes and no apparent solid area was noted. On microscopy, papillary serous adenocarcinoma arising from tubal wall was seen infiltrating focally into ovarian stroma; tubal epithelium showed dysplastic change. Sections from omentum showed numerous psammoma bodies.

  19. Laparoscopic management of fallopian tube prolapse masquerading as adenocarcinoma of the vagina in a hysterectomized woman

    Directory of Open Access Journals (Sweden)

    Kucuk Mustafa

    2002-01-01

    Full Text Available Abstract Background Fallopian tube prolapse as a complication of abdominal hysterectomy is a rare occurrence. A case with fallopian tube prolapse was managed by a combined vaginal and laparoscopic approach and description of the operative technique is presented. Case presentation A 39-year-old woman with vaginal prolapse of the fallopian tube after total abdominal hysterectomy presented with an incorrect diagnosis of adenocarcinoma of the vaginal apex. The prolapsed tube and cystic ovary were removed by vaginal and laparoscopic approach. The postoperative course went well. Conclusions Early or late fallopian tube prolapse can occur after total abdominal hysterectomy and vaginal hysterectomy. Symptoms consist of persistent blood loss or leukorrhea, dyspareunia and chronic pelvic pain. Vaginal removal of prolapsed tube with laparoscopic surgery may be a suitable treatment. The abdominal or vaginal approach used in surgical correction of prolapsed tubes must be decided in each case according to the patient's individual characteristics.

  20. MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian, Fallopian, or Peritoneal Cancer

    Science.gov (United States)

    2016-06-24

    Fallopian Tube Transitional Cell Carcinoma; Malignant Ovarian Clear Cell Tumor; Malignant Ovarian Endometrioid Tumor; Malignant Ovarian Serous Tumor; Ovarian Seromucinous Carcinoma; Ovarian Transitional Cell Carcinoma; Primary Peritoneal Serous Adenocarcinoma; Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Undifferentiated Fallopian Tube Carcinoma; Undifferentiated Ovarian Carcinoma

  1. Interleukin-1 is the initiator of fallopian tube destruction during Chlamydia trachomatis infection

    DEFF Research Database (Denmark)

    Hvid, Malene; Baczynska, Agata; Deleuran, Bent Winding;

    2007-01-01

    Chlamydia trachomatis infection is associated with severe Fallopian tube tissue damage leading to tubal infertility and ectopic pregnancy. To explore the molecular mechanisms behind infection an ex vivo model was established from human Fallopian tubes and examined by scanning electron microscopy...... tube following C. trachomatis infection. Because leukocytes are absent in the ex vivo model, this study strongly indicates that IL-1 is the initial proinflammatory cytokine activated by C. trachomatis infection....

  2. The clinical application of selective salpingography and fallopian tube recanalization in treating female infertility

    International Nuclear Information System (INIS)

    Objective: To evaluate the clinical efficacy of selective salpingography (SSG) and fallopian tube recanalization (FTR) in diagnosing and treating fallopian tubal infertility. Methods: SSG was performed in 459 patients and a total of 895 fallopian tubes were proved to be completely or incompletely occluded. Under fluoroscopic guidance, a catheter was managed to be placed in the tubal ostium, then a catheter and guide wire system was used to clear the proximal tube. The cumulative pregnancy rate within eighteen months after the treatment was calculated, and the postoperative tubal patency degree was compared with the preoperative one. Results: After FTR complete patency was achieved in 572 tubes(63.9%). For complete occluded tubes the postoperative patent rate was 80.3%(53/66), while it was 96.7% (802/829) for incomplete occluded tubes. During the follow-up period of 18 months, the pregnancy was confirmed in 43.9% patients(93/212), among which ectopic pregnancy was seen in 2.1% patients (2/93). The median procedure-conception interval was 8.2 months. The pregnancy rate was 51.3% (58/113) in patients with basically patent bilateral fallopian tubes, and it was 35.4% (35/99) in patients with incomplete patent fallopian tubes. Conclusion: The results clearly indicate that SSG together with FTR is a safe and effective method for the treatment of female infertility caused by proximal blockage or incomplete occlusion of the fallopian tubes. (authors)

  3. Clinical implications of accessory fallopian tube ostium in endometriosis and primary infertility.

    Science.gov (United States)

    Pereira, Nigel; Kligman, Isaac

    2016-07-01

    Several variations in fallopian tube anatomy may be noted during the evaluation of infertility. Some anatomical variants such as accessory tubal ostia are rare. A 31-year-old woman presented to our center with a 2-year history of primary infertility. Given her history of dysmenorrhea, a diagnostic laparoscopy was performed. Laparoscopy revealed a left utero-sacral endometriosis implant, which was resected. Although the left fallopian tube was normal, the right fallopian tube was noted to have two prongs with individual ostia. Tubal cannulation confirmed two separate ostia, with chromotubation showing free flow of dye through separate fimbrial ostia of the right fallopian tube. The current case highlights that accessory tubal ostia are rare müllerian duct anomalies seen during laparoscopy and can be associated with endometriois or primary infertility. PMID:27638894

  4. Human Fallopian Tube Mesenchymal Stromal Cells Enhance Bone Regeneration in a Xenotransplanted Model

    OpenAIRE

    Jazedje, Tatiana; Bueno, Daniela F; Almada, Bruno V. P.; Caetano, Heloisa; Czeresnia, Carlos E.; Perin, Paulo M.; Halpern, Silvio; Maluf, Mariangela; Evangelista, Lucila P.; Nisenbaum, Marcelo G.; Martins, Marília T.; Passos-Bueno, Maria R.; Zatz, Mayana

    2011-01-01

    We have recently reported that human fallopian tubes, which are discarded during surgical procedures of women submitted to sterilization or hysterectomies, are a rich source of human fallopian tube mesenchymal stromal cells (htMSCs). It has been previously shown that human mesenchymal stromal cells may be useful in enhancing the speed of bone regeneration. This prompted us to investigate whether htMSCs might be useful for the treatment of osteoporosis or other bone diseases, since they presen...

  5. The effectiveness of different interventional methods for partial fallopian tube obstruction: an analysis of 186 cases

    International Nuclear Information System (INIS)

    Objective: To evaluate selective salpingo-catheterization recanalization therapy in treating partial fallopian tube obstruction through comparing its clinical effectiveness with that of non-interventional radiology methods. Methods: During the period from January 2008 to October 2010, a total of 186 infertility women with partial fallopian tube obstruction, which was confirmed with hysterosalpingography, were encountered in authors' hospital. This study protocol was approved by our hospital ethics committee, and informed consent was obtained from all patients. According of different treatment methods, 186 patients were divided into two groups. Patients (n=78) in group A received non-interventional radiology methods, including hydrotubation, enema, laparoscopy, physical therapy and traditional Chinese medication, while patients (n=108) in group B received selective salpingo-catheterization recanalization therapy. All 186 patients were followed up for more than six months. Close observation on the pregnancy incidence after different treatments and fallopian tube patency was carried out. The clinical findings were documented. The results were statistically analyzed by using paired 'x2' test. Results: Half a year after different procedures, in group A the pregnancy rate was 12.82% (n=10), and different degrees of fallopian tube obstruction were found in 31.58% patients. Whereas in group B, during the same period of observation, the pregnancy rate was 58.33% (n=63), and partial occlusion in cornual region was seen in one patient (0.47%). Significant difference in both pregnancy rate and fallopian tube occlusion rate existed between two groups (P<0.05). Conclusion: Because of its minimal invasiveness, high effectiveness and safety, the selective salpingography together with fallopian tube recanalization procedures are well accepted by the patients. The selective salpingo-catheterization recanalization therapy is superior to non-interventional radiology methods in

  6. The comparison between Intrauterine Insemination and Fallopian Tube Sperm Perfusion Using FAST®System in Patients with Unexplained Infertility

    OpenAIRE

    Sepideh Peivandi; Shila Modanlu; Aghdas Ebadi

    2015-01-01

    Background: Controlled ovarian stimulation (COH) with intrauterine insemination (IUI) is commonly offered to infertile couples with patent fallopian tubes because it is simple, non-invasive and cost-effective technique. Another non-invasive method is fallopian tube sperm perfusion (FSP). This study was performed to compare the relative efficacy between FSP using fallopian sperm transfer (FAST) system and standard IUI in patients with unexplained infertility. Materials and Me...

  7. Serous papillary cystadenofibroma of the fallopian tube: A case report and short review of literature

    Directory of Open Access Journals (Sweden)

    Yasmeen Khatib

    2015-01-01

    Full Text Available Serous papillary cystadenofibromas (SPCAFs of the fallopian tube are very rare benign tumors of the female genital tract. They are usually asymptomatic and are found incidentally. Until now, only 18 cases of this tumor have been reported in the world literature. We report a case of SPCAF of the left fallopian tube in a 30-year-old female who presented with a large abdominal mass and pain. On computed tomography, a diagnosis of ovarian neoplasm was given. However, during surgery the tumor was found to arise from the fallopian tube and was treated with tubal cystectomy with sparing of the ovary. We present this unique case on account of its rarity, unusual presentation, and huge size along with a short review of literature.

  8. BLOCKED FALLOPIAN TUBES AND ITS MANAGEMENT WITH AYURVEDIC MEDICINE: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Kamat Rajeshwari V

    2012-08-01

    Full Text Available The present paper is based on clinical success story in a very interesting and encouraging casein blockage of both fallopian tubes. Success was achieved with unique classical Ayurvedic formulations after 6 months treatment which will be representeding the full paper.

  9. A RARE AND UNUSUAL CASE OF DERMOID CYST OF FALLOPIAN TUBE

    OpenAIRE

    Lalitha; Pradeep; Shwetha

    2014-01-01

    Benign solid teratomas within the fallopian tubes are very rare. They are found incidentally on laparotomy/by laparoscopy or mistaken for ovarian tumors or paraovarian cysts. Only 3 cases of teratomas have been reported. So this rare entity has been reported

  10. Primary malignant tumor of the fallopian tube : CT and MR features

    Energy Technology Data Exchange (ETDEWEB)

    Kahng, Yu Ri; Kim, Jeong Kon; Cho, Kyoung sik [Univ. of Ulsan College of Medicine, Seoul (Korea, Republic of)

    2001-10-01

    To determine the radiologic features of primary malignant tumors of the fallopian tube. By observing six computed tomograms and one MR image, we determined the radiologic features of seven pathologically proven primary malignant tumors of the fallopian tube. The location, size, internal appearances (cystic/mixed/solid) of the tumor were analysed, and the presence or absence of ipsilateral ovary, hydrosalpinx, intrauterine fluid collection, pelvic ascites and lymphadenopathy were determined. All seven tumors were located in unilateral adnexa. Their mean diameter was 3.5 (range, 1.5-6) cm, and their morphological appearance was solid in five cases and mixed in two. In no case were ipsilateral ovaries identified. Hydrosalpinx was noted in four cases (57%) and intrauterine fluid collection in five (71%). Pelvic ascites and lymphadenopathy were each observed in one case (14%). Although it is difficult to differentiate between primary malignant tumors of the fallopian tube and other adnexal tumors, a pelvic mass with hydrosalpinx and intrauterine fluid collection suggests a primary malignant tumor of the fallopian tube.

  11. Mycoplasmateceae species are not found in Fallopian tubes of women with tubo-peritoneal infertility

    Directory of Open Access Journals (Sweden)

    Alberto Costoya

    2012-06-01

    Full Text Available BACKGROUND: The role of mycoplasmas on the development and sequelae of pelvic inflammatory disease remains controversial. The objective of the present study is to correlate directly the presence of Mycoplasmateceae through polimerase chain reaction (PCR determinations in cervix and Fallopian tubes of infertile patients with tubo-peritoneal factor diagnosed through laparoscopy. METHODS: Thirty patients with tubo-peritoneal infertility and 30 normal fertile patients were included in the study; cervical samples and tubal flushings were obtained during laparoscopy. PCR determinations for the detection of genetic material of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealiticum, Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis in cervix and tubal flushings were performed. RESULTS: No Mycoplasmataceae species as "only" microorganisms were found in tubal flushings of tubo-peritoneal infertility patients, whereas three (10% fertile patients with normal tubes were positive for mycoplasma presence. This difference was not significant (p = 0.237. Among the 30 patients suffering from tubal infertility diagnosed through laparoscopy, Mycoplasmatecae species were not detected in the Fallopian tubes by PCR determinations, while in normal tubes from fertile patients these and other microorganisms could be found without distorting tubal anatomy. CONCLUSION: Mycoplasmateceae species were not detected in Fallopian tubes of women with tubo-peritoneal infertility.

  12. Inguinal Hernia Containing Uterus, Fallopian Tube, and Ovary in a Premature Newborn

    Science.gov (United States)

    Karadeniz Cerit, Kıvılcım; Ergelen, Rabia; Colak, Emel; Dagli, Tolga E.

    2015-01-01

    A female infant weighing 2,200 g was delivered at 34 weeks of gestation by vaginal delivery. She presented with an irreducible mass in the left inguinal region at 32 days of age. An ultrasonography (US) was performed and an incarcerated hernia containing uterus, fallopian tube, and ovary was diagnosed preoperatively. Surgery was performed through an inguinal approach; the uterus, fallopian tube, and ovary were found in the hernia sac. High ligation and an additional repair of the internal inguinal ring were performed. Patent processus vaginalis was found during contralateral exploration and also closed. The postoperative course was uneventful. After one year of follow-up, there have been no signs of recurrence. PMID:26351609

  13. Incarcerated femoral hernia containing ovary and fallopian tube in a 54-year-old

    OpenAIRE

    Coyle, David; Kavanagh, Nora; Mahmoud, Akthar; Lowery, Aoife J.; Khan, Waqar; Barry, Kevin

    2011-01-01

    While accounting for a small proportion of groin hernias, femoral hernias have the greatest propensity to incarcerate and strangulate leading to significant morbidity and mortality. The authors present a case of a 54-year-old multiparous female presenting with a new firm painful left-sided groin lump for 1 day. Incarcerated femoral hernia was diagnosed clinically and open surgical repair was undertaken. At surgery a viable ovary and fallopian tube were found in the hernial sac and returned to...

  14. Fiber optic laser light scattering measurement of ciliary function of the fallopian tube

    Science.gov (United States)

    Halbert, Sheridan A.; Lim, Kap; Lee, Wylie I.

    1990-07-01

    A fiber-optic laser light-scattering system (FLS) for measuring ciliary function was evaluated by means of three sets of in vitro experiments. First, FLS performance was compared to that of a previously proven benchtop laser system (BLS). Using tissue excised from rabbit fallopian tubes, ciliary beat frequency (CBF) of each sample was measured with FLS and BLS. Paired CBF measurements showed excellent correlation between the two systems (r =0.93). Second, the FLS was used to evaluate the dependency of CBF on temperature (T) by using tissue sampies of rabbit oviductal fimbna. Regression analysis of CBF vs T showed a linear relationship over the range of 18-37°C for both individual samples (r =0.98) and pooled data from all experiments (r = 0.84). Fmally, the relalionship between CBF and ciliary ovum transport rate (TR) was tested by using T to modulate CBF of rabbit fimbria, in vitro. The relationship was linear over the range of CBF from 10 to 30 Hz (r2 = 0.83). At 37°C, CBF = 31+/-1 Hz, and TR = O.12+/-.02 mm/sec. equal to ovum transport rate in situ. The FLS is a valuable tool for characterizing ciliary activity and thus ovum transport function. Owing to the fact that ciliary dyskinesia resulting from disease of the fallopian tube is associated with infeitility, the FLS may be useful to acquire data important to the clinical evaluation of fallopian tube function and female infertility.

  15. The Regulation of Nitric Oxide Synthase Isoform Expression in Mouse and Human Fallopian Tubes: Potential Insights for Ectopic Pregnancy

    Directory of Open Access Journals (Sweden)

    Junting Hu

    2014-12-01

    Full Text Available Nitric oxide (NO is highly unstable and has a half-life of seconds in buffer solutions. It is synthesized by NO-synthase (NOS, which has been found to exist in the following three isoforms: neuro nitric oxide synthase (nNOS, inducible nitric oxide synthase (iNOS, and endothelial nitric oxide synthase (eNOS. NOS activity is localized in the reproductive tracts of many species, although direct evidence for NOS isoforms in the Fallopian tubes of mice is still lacking. In the present study, we investigated the expression and regulation of NOS isoforms in the mouse and human Fallopian tubes during the estrous and menstrual cycles, respectively. We also measured isoform expression in humans with ectopic pregnancy and in mice treated with lipopolysaccharide (LPS. Our results confirmed the presence of different NOS isoforms in the mouse and human Fallopian tubes during different stages of the estrous and menstrual cycles and showed that iNOS expression increased in the Fallopian tubes of women with ectopic pregnancy and in LPS-treated mice. Elevated iNOS activity might influence ovulation, cilia beats, contractility, and embryo transportation in such a manner as to increase the risk of ectopic pregnancy. This study has provided morphological and molecular evidence that NOS isoforms are present and active in the human and mouse Fallopian tubes and suggests that iNOS might play an important role in both the reproductive cycle and infection-induced ectopic pregnancies.

  16. Local Interaction Between the Ovary, Fallopian Tube and Uterus

    Institute of Scientific and Technical Information of China (English)

    N.Einer-Jcnsen

    1992-01-01

    Counter current transfer of prostaglandins, inert gasses, steroid-and peptidehormones has been found between the utero-ovarian veins and the ovarian artery in man and several animal species, The substance transferred will, via the ovarian arterial blood, reach the ovary, tube and, in some speeies, the proximat part of the uterus in theipsifateralside Transfer has also been found.from the caudal uterine vein blood to the ipsilateral uterine artery. Preliminary results further indicate that local transfer cantake place of substances deposit ed in t he vaginal lumen.

  17. Selective fallopian tube catheterisation in female infertility: clinical results and absorbed radiation dose

    International Nuclear Information System (INIS)

    Clinical results of fluoroscopic fallopian tube catheterisation and absorbed radiation doses during the procedure were evaluated in 30 infertility patients with unilateral or bilateral tubal obstruction documented on hysterosalpingography. The staged technique consisted of contrast injection through an intrauterine catheter with a vacuum cup device, ostial salpingography with the wedged catheter, and selective salpingography with a coaxial microcatheter. Of 45 fallopian tubes examined, 35 (78 %) were demonstrated by the procedure, and at least one tube was newly demonstrated in 26 patients (87 %). Six of these patients conceived spontaneously in the follow-up period of 1-11 months. Four pregnancies were intrauterine and 2 were ectopic. This technique provided accurate and detailed information in the diagnosis and treatment of tubal obstruction in infertility patients. The absorbed radiation dose to the ovary in the average standardised procedure was estimated to be 0.9 cGy. Further improvement in the X-ray equipment and technique is required to reduce the radiation dose. (orig.). With 3 figs., 3 tabs

  18. “Histo-architecture of the rabbit fallopian tube following short-term RISUG implant”.

    Directory of Open Access Journals (Sweden)

    Mithilesh Pal

    2014-12-01

    Full Text Available RISUG ® (Reversible Inhibition of Sperm Under Guidance is an injectable contraceptive for male running under clinical trial phase- III. As RISUG was not tried in females, the present study was initiated to examine the tissue specific reaction and the histo-architecture of the fallopian tube, isthmus region, receive the polymer implant. Five non-pregnant female rabbits were allowed to retain the implant for 90 days. Thereafter, isthmuses along with other associated organs were removed and examined both macro- and micro-scopically. There were no gross changes in the isthmus region and other related organs like ampulla, uterus and ovary. Aggregates of RISUG ® implants were observed occupying spaces among villi, bulging with shed epithelium and mucus in the lumen, villi deviated from their normal perpendicular position. No lymphocytic infiltration in mucosa and tunica muscle layer was observed .The serosa showed normal histo-architecture in the implanted and adjoining isthmic wall. The above finding indicates that the drug is compatible with in the fallopian tube and therefore needs to be explored further for its contraceptive potential in females.

  19. Interventional fallopian tube recanalization combined with ozone injection in treating chronic obstructive salpingitis: an experimental study in rabbits

    International Nuclear Information System (INIS)

    Objective: To assess the therapeutic value of interventional fallopian tube recanalization (FTR) combined with ozone injection in treating chronic obstructive salpingitis in experimental rabbits in order to provide references for clinical application. Methods: The animal model of chronic obstructive salpingitis was established through interventional uterotubal catheterization in New Zealand white rabbits. A total of 40 rabbit models with salpingitis were randomly and equally divided into four groups: group A (30 μg/ml ozone), group B (40 μg/ml ozone), group C (conventional interventional treatment) and group D (modeling control group). Another ten healthy rabbits were used as a blank control group (group E). After interventional FTR was successfully finished, 10 ml of 30 μg/ml ozone and 40 μg/ml ozone was injected through the catheter into each fallopian tube in the rabbits of group A and group B respectively, while anti-inflammatory drug was given to the rabbits in group C, and 10 ml of saline was injected in the rabbits of both group D and group E. Four weeks after the treatment, the experimental rabbits were sacrificed, and the fallopian tubes were collected and sent for macroscopic and microscopic examination. Results: The recanalization rate of the fallopian tube in group A, B, C and D was 88.9%, 85.0%, 88.9% and 81.3%, respectively. The severity of salpingitis observed in group A, B and C was significantly improved when compared to that observed in group D (P 0.05). Conclusion: Additional use of ozone injection with the concentration of 30 μg/ml or 40 μg/ ml following interventional fallopian tube recanalization management can surely improve the chronic obstructive salpingitis to a certain degree in experimental rabbits. This technique might be advocated in clinical practice. (authors)

  20. Occupation and risk of primary fallopian tube carcinoma in Nordic countries

    DEFF Research Database (Denmark)

    Riska, A; Martinsen, J I; Kjaerheim, K;

    2012-01-01

    The aetiology of primary Fallopian tube carcinoma (PFTC) is poorly understood. Occupational exposures may contribute to PFTC risk. We studied incidence of PFTC in occupational categories in the Nordic female population aged 30-64 years during the 1960, 1970, 1980/1981 and/or 1990 censuses...... in Denmark, Finland, Iceland, Norway and Sweden. Standardized incidence ratios (SIRs) for the years following inclusion in the study up to 2005 were calculated for 53 occupations; the expected numbers of cases were based on PFTC incidence in the national populations. Altogether 2,206 PFTC cases were detected.......11-2.29, Obs = 32), nurses (1.49, 1.14-1.92, Obs = 60), shop workers (1.25, 1.07-1.46, Obs = 159) and clerical workers (1.20, 1.07-1.35, Obs = 271) and these sustained over times and different Nordic countries. There was a nonsignificant increased risk for PFTC among welders, printers, painters and chemical...

  1. Granisetron, Aprepitant, and Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Stage II, III, or IV Ovarian Cancer

    Science.gov (United States)

    2016-03-16

    Malignant Ovarian Mixed Epithelial Tumor; Nausea and Vomiting; Ovarian Brenner Tumor; Ovarian Clear Cell Cystadenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Cystadenocarcinoma; Ovarian Serous Cystadenocarcinoma; Stage II Ovarian Cancer; Stage IIA Fallopian Tube Cancer; Stage IIA Ovarian Cancer; Stage IIB Fallopian Tube Cancer; Stage IIB Ovarian Cancer; Stage IIC Fallopian Tube Cancer; Stage IIC Ovarian Cancer; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Cancer; Stage IIIA Primary Peritoneal Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Cancer; Stage IIIB Primary Peritoneal Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Cancer; Stage IIIC Primary Peritoneal Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Primary Peritoneal Cancer; Undifferentiated Ovarian Carcinoma

  2. Human fallopian tube mesenchymal stromal cells enhance bone regeneration in a xenotransplanted model.

    Science.gov (United States)

    Jazedje, Tatiana; Bueno, Daniela F; Almada, Bruno V P; Caetano, Heloisa; Czeresnia, Carlos E; Perin, Paulo M; Halpern, Silvio; Maluf, Mariangela; Evangelista, Lucila P; Nisenbaum, Marcelo G; Martins, Marília T; Passos-Bueno, Maria R; Zatz, Mayana

    2012-06-01

    We have recently reported that human fallopian tubes, which are discarded during surgical procedures of women submitted to sterilization or hysterectomies, are a rich source of human fallopian tube mesenchymal stromal cells (htMSCs). It has been previously shown that human mesenchymal stromal cells may be useful in enhancing the speed of bone regeneration. This prompted us to investigate whether htMSCs might be useful for the treatment of osteoporosis or other bone diseases, since they present a pronounced capacity for osteogenic differentiation in vitro. Based on this prior knowledge, our aim was to evaluate, in vivo, the osteogenic capacity of htMSCs to regenerate bone through an already described xenotransplantation model: nonimmunosuppressed (NIS) rats with cranial defects. htMSCs were obtained from five 30-50 years old healthy women and characterized by flow cytometry and for their multipotenciality in vitro capacity (osteogenic, chondrogenic and adipogenic differentiations). Two symmetric full-thickness cranial defects on each parietal region of seven NIS rats were performed. The left side (LS) of six animals was covered with CellCeram (Scaffdex)-a bioabsorbable ceramic composite scaffold that contains 60% hydroxyapatite and 40% β-tricalciumphosphate-only, and the right side (RS) with the CellCeram and htMSCs (10(6) cells/scaffold). The animals were euthanized at 30, 60 and 90 days postoperatively and cranial tissue samples were taken for histological analysis. After 90 days we observed neobone formation in both sides. However, in animals euthanized 30 and 60 days after the procedure, a mature bone was observed only on the side with htMSCs. PCR and immunofluorescence analysis confirmed the presence of human DNA and thus that human cells were not rejected, which further supports the imunomodulatory property of htMSCs. In conclusion, htMSCs can be used successfully to enhance bone regeneration in vivo, opening a new field for future treatments of osteoporosis

  3. A case of infertility with tuberculosis with multiple calcifications on both fallopian tubes

    Directory of Open Access Journals (Sweden)

    Meena Khatri

    2013-02-01

    Full Text Available Genital tract tuberculosis usually shows no symptoms and it is diagnosed as such incidentally during infertility investigations. In general, infertility is the most common clinical symptom of pelvic tuberculosis to the extent that it constitutes between 40 to 60 percent of the patients chief complaints. Female genital tuberculosis is still a major cause of infertility in India. This case highlights some of the well known facts about genital tuberculosis, that it is the relatively young female in the reproductive age group who are victim in female genital tuberculosis and infertility. In our case inspite of advanced genital tuberculosis, endometrial biopsy was negative for AFB and showed normal histopathology and diagnostic laparoscopy and biopsy from fallopian tubes revealed genital tuberculosis. Thus laparoscopy has definite place in the diagnosis of pelvic tuberculosis. Female genital tuberculosis is a major cause of infertility however diagnosis is sometime difficult and it becomes still more difficult when endometrial histopathology is normal therefore diagnostic laparoscopy is gold standard for confirmation of genital tuberculosis with its added advantages of complete evaluation of uterus, tubes, ovaries and operative intervention in the same sitting. [Int J Reprod Contracept Obstet Gynecol 2013; 2(1.000: 111-113

  4. The Effect of Estradiol and Progesterone on Toll Like Receptor Gene Expression in A Human Fallopian Tube Epithelial Cell Line

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    Zahra Zandieh

    2016-02-01

    Full Text Available Objective: Toll like receptors (TLRs are one of the main components of the innate immune system. It has been reported that expression of these receptors are altered in the female reproductive tract (FRT during menstrual cycle. Here we used a fallopian tube epithelial cell line (OE-E6/E7 to evaluate the effect of two sex hormones in modulating TLR expression. Materials and Methods: In this experimental study, initially TLR gene expression in OEE6/ E7 cells was evaluated and compared with that of fallopian tube tissue using quantitative real time-polymerase chain reaction (qRT-PCR and immunostaining. Thereafter, OE-E6/E7 cells were cultured with different concentrations of estradiol and progesterone, and combination of both. qRT-PCR was performed to reveal any changes in expression of TLR genes as a result of hormonal treatment. Results: TLR1-10 genes were expressed in human fallopian tube tissue. TLR1-6 genes and their respective proteins were expressed in the OE-E6/E7 cell line. Although estradiol and progesterone separately had no significant effect on TLR expression, their combined treatment altered the expression of TLRs in this cell line. Also, the pattern of TLR expression in preovulation (P, mensturation (M and window of implantation (W were the same for all TLRs with no significant differences between P, M and W groups. Conclusion: These data show the significant involvement of the combination of estradiol and progesterone in modulation of TLR gene expression in this human fallopian tube cell line. Further experiments may reveal the regulatory mechanism and signalling pathway behind the effect of sex hormones in modulating TLRs in the human FRT.

  5. Histological studies of the effects of monosodium glutamate of the Fallopian tubes of adult female Wistar rats

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    Andrew Osayame Eweka

    2010-01-01

    Full Text Available Background: The effect of monosodium glutamate used as food additive on the fallopian tubes of adult Wistar rat was investigated. Material and Methods: Adult female Wistar rats (n=24 of average weight of 230g were randomly assigned into three groups A, B and C in each group (n=8. The treatment groups (A & B were given 0.04mg/kg and 0.08mg/kg of monosodium glutamate thoroughly mixed with the growers′ mash, respectively on a daily basis. The control group (C received equal amount of feeds (Growers′ mash without monosodium glutamate added for fourteen days. The growers′ mash was obtained from Edo Feeds and Flour Mill Ltd, Ewu, Edo State and the rats were given water liberally. The rats were sacrificed on day fifteen of the experiment. The fallopian tubes were carefully dissected out and quickly fixed in 10% buffered formaldehyde for routine histological procedures. Result: The histological findings in the treated groups showed evidence of cellular hypertrophy, degenerative and atrophic changes, and lysed red blood cells in lumen with the group that received 0.08mg/kg of monosodium glutamate more severe. Conclusion: MSG may have some deleterious effects on the fallopian tubes of adult female Wistar rats at higher doses and by extension may contribute to the causes of female infertility. It is recommended that further studies aimed at corroborating these findings be carried out.

  6. Effect of Monosodium Glutamate on the Epithelial Height of Fallopian Tube of Rat and its Prevention with Diltiazem

    International Nuclear Information System (INIS)

    Objective: To study the effect of monosodium glutamate on the fallopian tube of adult Sprague Dawley rat and prevention of this effect with diltiazem. Study Design: Laboratory based randomized controlled trial. Place and Duration of the Study: Anatomy Department, Army Medical College, Rawalpindi in collaboration with National Institute of Health (NIH), Islamabad from 9th April - 23rd April 2012. Material and Methods: In this study 30 adult female Sprague Dawley rats of average weight of 500 g were randomly assigned into three groups A (control group), B and C (experimental groups) with 10 rats in each group. The experimental group B was given 0.08 mg/kg of monosodium glutamate (MSG) orally and experimental group C was given 0.08 mg/kg of MSG and 10 mg/kg of diltiazem in distilled water orally for 14 days. The control group (A) received only laboratory diet prepared at NIH Islamabad with liberal water intake. The rats were sacrificed on the 15th day of the experiment. The fallopian tubes (F.T) were carefully dissected out and fixed in 10% formalin for routine histological examination. Result: The histological findings in the experimental group B showed evidence of an increase in epithelial height whereas no such finding was observed in groups A and there was a minor increase in epithelial height in group C. Conclusion: MSG causes an increase in epithelial height of fallopian tubes in adult female rats but treatment with diltiazem prevents this effect. (author)

  7. Primary Carcinoma in the Fallopian Tube: A Two Cases Report Carcinoma primario de la trompa de Falopio: presentación de dos casos

    Directory of Open Access Journals (Sweden)

    Myriam García Tirada

    2011-11-01

    Full Text Available Primary carcinoma in the fallopian tube is a rare gynecological tumor. Its preoperative diagnosis is difficult because of its insidious and silent course. It is usually performed in the postoperative stage. This carcinoma is most frequently presented in post menopausal women. Its clinical and histological behavior is often similar to that of an ovarian cancer. In literature there are reports on the association between ovarian and endometrial cancer. Nevertheless, there are but few references to their association with fallopian tubes cancer. Two cases of primary cancer in the fallopian tubes, diagnosed in a 6 months period through post-surgical histology, that were treated in the Gynecology Service of the ¨Enrique Cabrera¨ General Teaching Hospital are presented. Their preoperative diagnoses were endometrial adenocarcinoma and ovarian cancer. It is relevant that one patient, with 44 years old, was diagnosed through endometrial biopsy performed to remove an intra uterine device. The result of that study was an endometrial adenocarcinoma that required surgery.El carcinoma primario de la trompa de Falopio es un tumor ginecológico raro. Su diagnóstico pre- operatorio se dificulta por su curso insidioso y silente, generalmente se realiza en el post-operatorio. Se presenta con mayor frecuencia en mujeres post menopaúsicas y clínica e histológicamente se comporta en muchas ocasiones como un cáncer de ovario. En la literatura se ha reportado la asociación entre cáncer de ovario y endometrio pero muy pocos han descrito la asociación de estos, con el cáncer de la trompa de Falopio. Se presentan dos casos de cáncer primario de la trompa de Falopio, diagnosticados en un período de 6 meses por histología post-quirúrgica, intervenidos en el Servicio de Ginecología del Hospital General Docente ¨Enrique Cabrera¨ y cuyos diagnósticos pre-operatorios fueron: adenocarcinoma de endometrio y cáncer de ovario. Es llamativo, que una de las

  8. Quinacrine-induced occlusive fibrosis in the human fallopian tube is due to a unique inflammatory response and modification of repair mechanisms.

    Science.gov (United States)

    Growe, Roger G; Luster, Michael I; Fail, Patricia A; Lippes, Jack

    2013-04-01

    Quinacrine has been widely used in treatment of parasitic diseases such as malaria and giardiasis, and in the treatment of autoimmune diseases. Quinacrine has also been used as an effective substitute for surgical contraception by causing occlusion of the fallopian tube. This minimally invasive treatment protocol involves intrauterine insertion of the drug in the form of pellets and has been studied in humans in a number of countries, including the United States. Despite its development in the 1970s, the cellular and molecular events induced by quinacrine in the human fallopian tube have not been described. Here we describe a plausible mechanism for quinacrine action in the fallopian tube. This is manifested as an acute pro-inflammatory response in the uterus and fallopian tube, characterized by loss of epithelial cell adhesion. This response relies on properties of gated channels found on the surface of epithelial cells in the reproductive tract. While the uterus returns to normal, the inflammatory response affects the uterotubal junction and transmural segment of the human fallopian tube, and initiates formation of mature collagen in the lumen of the fallopian tube, resulting in its permanent occlusion. The response within the fallopian tube appears similar to the protective mechanisms that have evolved in women to minimize the likelihood of systemic infection from Neisseria gonorrhoeae, and to some extent from Chlamydia trachomatis. This review could assist in development of experimental models used in investigating the mechanisms of fibrotic responses in humans as well as development of techniques for permanent non-surgical female contraception. PMID:23453701

  9. Fluoroscopically guided fallopian tube recanalization with a simplified set of instruments; Durchleuchtungsgesteuerte Eileiter-Rekanalisation mit vereinfachtem Instrumentarium

    Energy Technology Data Exchange (ETDEWEB)

    Schmitz-Rode, T.; Guenther, R.W. [Technische Hochschule Aachen (Germany). Klinik fuer Radiologische Diagnostik; Neulen, J. [Technische Hochschule Aachen (Germany). Frauenklinik fuer gynaekologische Endokrinologie und Reproduktionsmedizin

    2004-10-01

    Purpose: Fluoroscopically guided transcervical fallopian tube recanalization is recognized as an important step in the workup of female infertility. In the present study, a simplified set of recanalization instruments was tested. Materials and Methods: Forty-two women with infertility and sonographically confirmed or suspected uni- or bilateral tubal occlusion were examined. After vaginal placement of a plastic speculum and fixation of a tenaculum, a 4F glide catheter with a 0.89 mm glidewire was advanced transcervically. After documentation of tubal occlusion by hysterosalpingography, the uterotubal junction was catheterized with the same instruments. Under fluoroscopic guidance, the glidewire was negotiated beyond the intramural portion of the tube. Selective salpingography documented the outcome of the recanalization. Results: Hysterosalpingography confirmed tubal occlusions in 26 of 42 patients (in 12 cases unilateral and in 14 cases bilateral). Fallopian tube recanalization was successful in 23 of 26 patients (technical success rate of 88%). The resulting fertility rate was 30% (7/23), without any ectopic pregnancy. Complications such as tubal perforation, infection, or bleeding did not occur. Tubal catheterization was straightforward and smooth in 17/23 cases. For a hyperflexed uterus (6/23), a curved tip of the catheter was helpful in tubal probing. (orig.)

  10. CB1 expression is attenuated in Fallopian tube and decidua of women with ectopic pregnancy.

    Directory of Open Access Journals (Sweden)

    Andrew W Horne

    Full Text Available BACKGROUND: Embryo retention in the Fallopian tube (FT is thought to lead to ectopic pregnancy (EP, a considerable cause of morbidity. In mice, genetic/pharmacological silencing of cannabinoid receptor Cnr1, encoding CB1, causes retention of embryos in the oviduct. The role of the endocannabinoids in tubal implantation in humans is not known. METHODS AND FINDINGS: Timed FT biopsies (n = 18 were collected from women undergoing gynecological procedures for benign conditions. Endometrial biopsies and whole blood were collected from women undergoing surgery for EP (n = 11; management of miscarriage (n = 6, and termination of pregnancy (n = 8. Using RT-PCR and immunohistochemistry, CB1 mRNA and protein expression levels/patterns were examined in FT and endometrial biopsies. The distribution of two polymorphisms of CNR1 was examined by TaqMan analysis of genomic DNA from the whole blood samples. In normal FT, CB1 mRNA was higher in luteal compared to follicular-phase (p<0.05. CB1 protein was located in smooth muscle of the wall and of endothelial vessels, and luminal epithelium of FT. In FT from women with EP, CB1 mRNA expression was low. CB1 mRNA expression was also significantly lower (p<0.05 in endometrium of women with EP compared to intrauterine pregnancies (IUP. Although of 1359G/A (rs1049353 polymorphisms of CNR1 gene suggests differential distribution of genotypes between the small, available cohorts of women with EP and those with IUP, results were not statistically significant. CONCLUSIONS: CB1 mRNA shows temporal variation in expression in human FT, likely regulated by progesterone. CB1 mRNA is expressed in low levels in both the FT and endometrium of women with EP. We propose that aberrant endocannabinoid-signaling in human FT leads to EP. Furthermore, our finding of reduced mRNA expression along with a possible association between polymorphism genotypes of the CNR1 gene and EP, suggests a possible genetic predisposition to EP that

  11. Advantages and disadvantages of hysterosonosalpingography in the assessment of the reproductive status of uterine cavity and fallopian tubes

    Energy Technology Data Exchange (ETDEWEB)

    Radic, Vanja; Canic, Tomislav; Valetic, Josip; Duic, Zeljko

    2005-02-01

    Background: Hysterosonosalpingography as a contrast ultrasound method is safer, cheaper and easier to perform than hysterosalpingography in the assessment of the uterine cavity and fallopian tubes. Is it feasible for all patients? Which is the main problem in the evaluation of target structures by ultrasound? Methods: In a prospective study, 68 patients in the initial stage of the infertility treatment were examined by hysterosonosalpingography using saline NaCl infundibile[reg] and Echovist[reg] as contrast media. Subsequently, further status of the tubes and uterine cavity was assessed by the 'gold standards', laparoscopy and hysteroscopy. Results: Sensitivity and specificity of hysterosonosalpingography using NaCl infundibile[reg] for evaluation of the uterine cavity was 100 and 88.8%, respectively. Negative predictive value was 100% and positive predictive value 97%. Sensitivity and specificity of the method for the assessment of the tubal status was 100 and 66%, respectively, negative predictive value was 100% and positive predictive value was 61%. For the assessment of tubal patency using positive contrast Echovist[reg] the method has shown 100% sensibility and negative predictive value again but it reached a specificity of 77% and a positive predictive value of 70%. There were no evident complications during or after the procedure. Conclusion: Hysterosonosalpingography is useful in making decisions regarding further procedures for the diagnosis and treatment of infertility. Uterine cavity evaluation using saline is the method of choice. Tubal patency can be assessed only under ideal sonographic conditions. The method is feasible for early assessment of the reproductive status of uterine cavity and fallopian tubes as a simple, safe and cheap outpatient method prior to any following invasive procedure or even histerosalpingography.

  12. Ovarian Cancer Stage I

    Science.gov (United States)

    ... An inset shows cancer cells in the pelvic peritoneum. Also shown are the fallopian tubes, uterus, cervix, ... c) cancer cells are found in the pelvic peritoneum. Topics/Categories: Anatomy -- Gynecologic Cancer Types -- Ovarian Cancer ...

  13. A rare case of invasive mucinous adenocarcinoma of fallopian tube fimbria with metastasis to ipsilateral ovary, uterine serosa, myometrium and pelvis: Case report and review of literature

    OpenAIRE

    Sharon X. Liang, MD, PhD; Tamar C. Brandler, MD, MS; Diana Contreras, MD; Rajasree Roy, MD; Liang Cheng, MD; Oluwole Fadare, MD

    2015-01-01

    Mucinous adenocarcinoma of the fallopian tube is exceptionally rare and the detailed clinicopathologic features of these tumors have not yet been reported in English literature. Here we report a moderately differentiated mucinous adenocarcinoma arising in the tubal fimbria in a 70-year-old woman. Patient had a history of cholecystectomy for gallstones and gastric banding who presented with gastrointestinal discomfort and was found to have a large adnexal mass on imaging studies. Serum CA-125 ...

  14. Psychosexual Intervention in Patients With Stage I-III Gynecologic or Breast Cancer

    Science.gov (United States)

    2016-05-02

    Ovarian Sarcoma; Ovarian Stromal Cancer; Stage I Uterine Sarcoma; Stage I Vaginal Cancer; Stage I Vulvar Cancer; Stage IA Cervical Cancer; Stage IA Endometrial Carcinoma; Stage IA Fallopian Tube Cancer; Stage IA Ovarian Epithelial Cancer; Stage IA Ovarian Germ Cell Tumor; Stage IA Primary Peritoneal Cavity Cancer; Stage IB Cervical Cancer; Stage IB Endometrial Carcinoma; Stage IB Fallopian Tube Cancer; Stage IB Ovarian Epithelial Cancer; Stage IB Ovarian Germ Cell Tumor; Stage IB Primary Peritoneal Cavity Cancer; Stage IC Fallopian Tube Cancer; Stage IC Ovarian Epithelial Cancer; Stage IC Ovarian Germ Cell Tumor; Stage IC Primary Peritoneal Cavity Cancer; Stage II Endometrial Carcinoma; Stage II Gestational Trophoblastic Tumor; Stage II Uterine Sarcoma; Stage II Vaginal Cancer; Stage II Vulvar Cancer; Stage IIA Cervical Cancer; Stage IIA Fallopian Tube Cancer; Stage IIA Ovarian Epithelial Cancer; Stage IIA Ovarian Germ Cell Tumor; Stage IIA Primary Peritoneal Cavity Cancer; Stage IIB Cervical Cancer; Stage IIB Fallopian Tube Cancer; Stage IIB Ovarian Epithelial Cancer; Stage IIB Ovarian Germ Cell Tumor; Stage IIB Primary Peritoneal Cavity Cancer; Stage IIC Fallopian Tube Cancer; Stage IIC Ovarian Epithelial Cancer; Stage IIC Ovarian Germ Cell Tumor; Stage IIC Primary Peritoneal Cavity Cancer; Stage III Gestational Trophoblastic Tumor; Stage III Uterine Sarcoma; Stage III Vaginal Cancer; Stage III Vulvar Cancer; Stage IIIA Cervical Cancer; Stage IIIA Endometrial Carcinoma; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Epithelial Cancer; Stage IIIA Ovarian Germ Cell Tumor; Stage IIIA Primary Peritoneal Cavity Cancer; Stage IIIB Cervical Cancer; Stage IIIB Endometrial Carcinoma; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Epithelial Cancer; Stage IIIB Ovarian Germ Cell Tumor; Stage IIIB Primary Peritoneal Cavity Cancer; Stage IIIC Endometrial Carcinoma; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Epithelial Cancer; Stage IIIC Ovarian Germ Cell

  15. Human fallopian tube epithelium constitutively expresses integrin endometrial receptivity markers: no evidence for a tubal implantation window.

    Science.gov (United States)

    Brown, J K; Shaw, J L V; Critchley, H O D; Horne, A W

    2012-03-01

    Understanding of ectopic implantation within the Fallopian tube (FT) is limited. In the human uterus, the putative 'window of implantation' in the mid-luteal phase of the menstrual cycle is accompanied by increased endometrial epithelial expression of the integrins α(1)β(1), α(4)β(1) and α(v)β(3) and its ligand osteopontin. Similar cyclical changes in FT integrin expression have been proposed to contribute to ectopic implantation, but supporting data are limited. In the current study, we present quantitative data on human FT transcription and translation of the integrin subunits α(1), α(4), α(V), β(1) and β(3) during the follicular and mid-luteal phases of the menstrual cycle, together with a supporting immuocytochemical analysis of their spatial distribution within the FT, and that of osteopontin. In contrast to previous studies, our data indicate that all five integrin receptivity markers are constitutively transcribed and translated in the FT, with no evidence for changes in their expression or distribution during the window of implantation in the mid-luteal phase of the cycle. Furthermore, we could find no evidence for cyclic redistribution of the integrin α(v)β(3) ligand osteopontin within the FT. Although we do not rule out the involvement of integrin endometrial receptivity markers in the establishment of ectopic pregnancy, our findings do not support their differential expression during a tubal implantation window. PMID:22002573

  16. Hysterosalpingographic Appearances of Female Genital Tract Tuberculosis: Part I. Fallopian Tube

    Directory of Open Access Journals (Sweden)

    Firoozeh Ahmadi

    2014-01-01

    Full Text Available Female genital tuberculosis (TB remains as a major cause of tubal obstruction leading to infertility, especially in developing countries. The global prevalence of genital tuberculosis has increased during the past two decades due to increasing acquired immunodeficiency syndrome (AIDS. Genital TB is commonly asymptomatic, and it is diagnosed during infertility investigations. Despite of recent advances in imaging tools, such as computerized tomography (CT scan, magnetic resonance imaging (MRI and ultrasongraphy, hysterosalpingography is still the standard screening test for evaluation of tubal infertility and a valuable tool for diagnosis of female genital tuberculosis. Tuberculosis gives rise to various appearances on hysterosalpingography (HSG from non-specific changes to specific findings. The present pictorial review illustrates and describes specific and non-specific radiographic features of female genital tuberculosis in two parts. Part I presents specific findings of tuberculosis related to tubes such as "beaded tube", "golf club tube", "pipestem tube", "cobble stone tube" and "leopard skin tube". Part II describes adverse effects of tuberculosis on structure of endometrium and radiological specific findings such as "dwarfed" uterus with lymphatic intravasation and occluded tubes, "T-shaped" tuberculosis uterus, "pseudounicornuate" uterus and "Collar-stud abscess", which have not been encountered in the majority of non-tuberculosis cases.

  17. Prolapso de tuba uterina após histerectomia vaginal: relato de caso Fallopian tube prolapse after vaginal hysterectomy: a case report

    Directory of Open Access Journals (Sweden)

    Maurício B. Noviello

    2003-12-01

    Full Text Available O prolapso de tuba uterina é complicação rara após histerectomia, com aproximadamente 80 casos descritos na literatura. A sintomatologia é inespecífica, podendo incluir sangramento genital, dispareunia e dor pélvica crônica. O diagnóstico diferencial deve ser feito com granuloma de cúpula vaginal e carcinoma de vagina. O tratamento deve ser individualizado, podendo ser realizado por via vaginal, abdominal ou laparoscópica. Relatamos o caso de uma paciente, 47 anos, com miomatose uterina, submetida a histerectomia vaginal, evoluindo com prolapso de tuba uterina após 11 meses de pós-operatório. O exame especular evidenciava lesão vegetante, friável e sangrante localizada na cúpula vaginal. Esses achados clínicos sugeriam o diagnóstico de prolapso de tuba uterina. A paciente foi submetida a nova intervenção cirúrgica, com ressecção da tuba uterina por via vaginal. O exame natomopatológico confirmou o diagnóstico e a paciente evoluiu com remissão completa da sintomatologia.Fallopian tube prolapse is a rare complication after hysterectomy, with approximately 80 cases described in the literature. The symptoms are nonspecific including vaginal bleeding, dyspareunia and chronic pelvic pain. The differential diagnosis must be done with granulation tissue of the vaginal cuff and vaginal carcinoma. The treatment should be individualized, and is possible to be done by vaginal, abdominal or laparoscopic approach. We report a case of a 47-year-old woman with myoma who was submitted to a vaginal hysterectomy and evolved with fallopian tube prolapse 11 months after surgery. Specular examination showed a fungating, friable and bleeding lesion at the vaginal cuff. The clinical findings suggested the diagnosis of fallopian tube prolapse. The patient was submitted to a new surgical intervention with resection of the left fallopian tube. The histologic examination confirmed the diagnosis and the patient evolved with complete remission of

  18. The Effect of Low Dose of Lead Acetate on the Fallopian Tubes and the Role of Garlic Extract—A Histomorphic Study on Mouse

    Directory of Open Access Journals (Sweden)

    Naureen Waseem

    2015-02-01

    Full Text Available This study aimed to investigate the effect of lead acetate on the fallopian tube of adult mice and the possible effect of garlic extract in a Laboratory Based Randomized Control Trial. In this study, 30 female BALBc mice were selected and randomly divided into three groups. Ten animals were placed in each group. Group A being the control received only the laboratory diet. Group B was given lead acetate at a dose of 30 mg/kg/day. Group C was given lead acetate at 30 mg/kg/day and garlic extract at 500 mg/kg/day. All treatments were given through oral gavage tube for 60 days. The mice were sacrificed and dissected at the end of 60 days. The fallopian tubes were carefully dissected out and fixed in 10% formalin for routine histological examination. The histological findings in experimental group B showed increase in epithelial height, whereas no such findings were observed in group A and there was slight increase in height in group C. The lead acetate affected the epithelial height in lead acetate treated group which improved when cotreated with garlic extract.

  19. Multidetector computed tomography virtual hysterosalpingography in the investigation of the uterus and fallopian tubes

    Energy Technology Data Exchange (ETDEWEB)

    Carrascosa, Patricia [Diagnostico Maipu, Av. Maipu 1668, Vicente Lopez B1602ABQ, Buenos Aires (Argentina)], E-mail: patriciacarrascosa@diagnosticomaipu.com.ar; Baronio, Mariano [CEGYR, Viamonte 1438, Capital Federal C1055ABB (Argentina); Capunay, Carlos; Lopez, Elba Martin; Vallejos, Javier [Diagnostico Maipu, Av. Maipu 1668, Vicente Lopez B1602ABQ, Buenos Aires (Argentina); Borghi, Mario; Sueldo, Carlos; Papier, Sergio [CEGYR, Viamonte 1438, Capital Federal C1055ABB (Argentina)

    2008-09-15

    Objective: To compare the efficacy of multidetector CT virtual hysterosalpingography (MDCT-VH) with conventional X-ray hysterosalpingography (HSG) in the evaluation of patients with diagnosis of infertility. Methods: Sixty patients with diagnosis of infertility scheduled to perform a HSG, were evaluated with 16-row (n = 50) and 64-row (n = 10) MDCT-VH. In 35 patients the examination was performed without a tenaculum. The HSGs were carried out using standard technique. The HSG and MDCT-VH findings were compared. The duration for both examinations and patient discomfort were documented. The sensitivity and specificity of MDCT-VH for the detection of uterine pathology and tubal obstruction were calculated using the exact binomial method. Agreement between the two methods was assessed by the Cohen's kappa method (k). Results: The mean duration for MDCT-VH (16 and 64-rows) was 5 {+-} 3 min, whereas for HSG was 28 {+-} 3. The MDCT-VH without a tenaculum was the procedure with less patient discomfort. Sensitivity, specificity and inter-method agreement for the detection of uterine pathology were 100%, 92% and k = 0.92 for 16-row MDCT-VH and 100%, 100% and k = 1 for 64-row MDCT-VH, respectively. Sensitivity and specificity for detection of tubal obstruction were 80% and 80% for 16-row MDCT-VH and 100% and 100% for 64-row MDCT-VH, respectively; inter-method agreement for the visualization of the tubes was k = 0.54 for 16-row MDCT-VH and k = 1 for 64-row MDCT-VH. Conclusion: This study demonstrated the feasibility of evaluating the female reproductive system by MDCT-VH. 64-Row MDCT-VH could be an alternative diagnostic technique in the infertility workup algorithm. A larger study is in progress to validate these encouraging results.

  20. The relevance of adjuvant therapy in primary carcinoma of the Fallopian tube, Stages I and II: Irradiation vs. chemotherapy

    International Nuclear Information System (INIS)

    Introduction: Primary carcinoma of the Fallopian tube (FTC) is a rare but extremely aggressive neoplasm. It must be expected to cause up to 40% of tumor-related deaths even in Stage I, and up to 57% in Stage II. Due to its rarity, there exist only a few and divergent reports on the value of adjuvant therapy. Therefore the present study aims at evaluating the influence of postoperative adjuvant therapy on FTC by studying the effects of irradiation and chemotherapy on the overall survival of patients in Stages I and II. Patients and Methods: We investigated 95 cases of FTC in Stages I (n = 66) and II (n = 29) in a retrospective multicenter study. Group I (n = 32) are patients who underwent a complete irradiation with cobalt or photon energies of 23 MV (administering a daily dose of 2 Gy resulted in a total of 45-52 Gy in the pelvic areas). Group II (n = 31) consists of those cases who received postoperative chemotherapy with platinum. Thirty-two women were excluded from this study because they had other chemotherapies, incomplete irradiation, or no adjuvant therapy at all. Results: Median survival time was 57 months in Group I patients (95% confidence interval 33-81 months), compared to 73 months (95% confidence interval, 68-78 months) in the chemotherapeutically treated Group II. This difference did not prove to be statistically significant (p = 0.476). If primary surgical therapy is included in the evaluation, and patients with total abdominal hysterectomy (TAH) and bilateral salpingo-oophorectomy (BSO) are compared to those with additional radical lymphadencetomy (TAH+BSO+lymph nodes), the latter group's overall survival essentially improves but fails to reach statistical significance. Their 5-year survival rate is 83% against 58% in the TAH+BSO group (p 0.12). Conclusion: Chemotherapy and irradiation are two adjuvant therapies that are similarly effective in FTC of Stages I and II, with chemotherapy being preferred at the present time. Primary surgical treatment

  1. Genetics Home Reference: ovarian cancer

    Science.gov (United States)

    ... that form the lining of the abdomen (the peritoneum). This form of cancer, called primary peritoneal cancer, ... that begin in the ovaries, fallopian tubes, and peritoneum are so similar and spread easily from one ...

  2. Gravidez ectópica tubária bilateral: relato de caso A bilateral fallopian tube pregnancy: a case report

    Directory of Open Access Journals (Sweden)

    Assis Oberdan Posser

    1998-07-01

    Full Text Available Gestação ectópica bilateral é a forma mais rara de gestação gemelar, considerando que menos de 250 casos foram relatados na literatura. Nosso caso preenche o critério diagnóstico determinado por Norris9 que requer a demonstração de vilos coriônicos em cada tuba de uterina. Relatamos o caso de uma mulher multípara de 36 anos de idade que desenvolveu um episódio de abdômen agudo hemorrágico. Uma laparotomia realizada com anestesia geral revelou hemoperitônio de 1,8 litros; ambas tubas uterinas aumentadas de volume e com laceração de suas paredes e presença de dois embriões medindo 2,7 e 3,0 cm de comprimento, livres no sangue intra-abdominal. Apresentamos uma revisão da literatura a respeito da gestação ectópica bilateral.Bilateral ectopic pregnancy is the most unusual twin gestation considering that less than 250 cases have been reported in the literature. Our case fulfills the diagnostic criterion determined by Norris9 which requires demonstration of chorionic villi in each fallopian tube. We report the case of a 36-year-old multiparous woman who had an hemorrhagic acute abdomen. A laparotomy performed under general anesthesia revealed hemoperitoneum of 1.8 liters and both swelled tubes with laceration of their walls, besides two embryos with 2,7 and 3,0 cm in length free in the intra-abdominal blood. A literature review on bilateral ectopic pregnancy is presented.

  3. A rare case of invasive mucinous adenocarcinoma of fallopian tube fimbria with metastasis to ipsilateral ovary, uterine serosa, myometrium and pelvis: Case report and review of literature

    Directory of Open Access Journals (Sweden)

    Sharon X. Liang, MD, PhD

    2015-06-01

    Full Text Available Mucinous adenocarcinoma of the fallopian tube is exceptionally rare and the detailed clinicopathologic features of these tumors have not yet been reported in English literature. Here we report a moderately differentiated mucinous adenocarcinoma arising in the tubal fimbria in a 70-year-old woman. Patient had a history of cholecystectomy for gallstones and gastric banding who presented with gastrointestinal discomfort and was found to have a large adnexal mass on imaging studies. Serum CA-125 was moderately elevated. Recent mammography, upper endoscopy and colonoscopy were completely normal. She underwent surgical staging for the adnexal mass. Frozen section and final pathology diagnosis revealed moderately differentiated adenocarcinoma arising in the left fimbria. Carcinoma had spread to the ipsilateral ovary and pelvic soft tissue at the time of her presentation. Tumor was strongly immunoreactive to CK7 and CEA, and was negative for CK20, CDX-2, PAX-8, WT-1, p16, ER, and vimentin. TP53 showed wild-type phenotype by immunohistochemistry. Molecular studies showed no mutation in codon 12 and 13 of the k-ras gene, and no mutation was detected in the BRAF and EGFR genes. In addition, the non-tumorous fimbria epithelium showed a spectrum of mucinous alterations with variable nuclear atypia: cytologically bland areas that were reminiscent of mucinous metaplasia were positive for p53 and showed minimal proliferation as assessed by Ki-67, and cytologically atypical stratified mucinous epithelium that was positive for p53 and Ki-67. The patient received 3 cycles of Folfox and was regularly followed at a 3–6 month interval. Her carcinoma recurred in abdomen at 32 months post surgery. After excluding the possibility of an extra-gynecologic tract primary through extensive clinical investigations and post-surgical follow-up, we concluded that this tumor most likely represented a mucinous adenocarcinoma of tubal origin.

  4. 输卵管Sonovue超声造影与碘海醇X线造影的对比分析%Comparison of Sonovue contrast-enhanced ultrasound and Iohexol X-ray hysterosalpingogram for fallopian tube assessment

    Institute of Scientific and Technical Information of China (English)

    王士琴; 袁伟

    2013-01-01

      目的比较输卵管Sonovue超声造影与碘海醇X线造影的结果,以期提高超声造影的准确率。方法对45例不孕不育患者,分别在B超下行Sonovue输卵管造影,在X线下行碘剂造影。结果B超:输卵管通畅者35例(66条),通而不畅7例(13条),不通者7例(10条);X线:输卵管通畅者38例(73条),通而不畅4例(7条),不通者6例(9条)。结论输卵管Sonovue超声造影诊断准确率略低于碘海醇X线造影。%  Objective To compare Sonovue contrast-enhanced hysterosonography(CEUS)and Iohexol X-ray hysterosalpingography(HSG).Methods Forty-five patients with infertility underwent CEUS of fallopian tubes using Sonovue followed by Iohexol X-ray HSG.Results Sixty-six fallopian tubes in 35 patients were clearly demonstrated on CEUS. Contrast flow was impeded in 13 tubes of 7 patients. Ten tubes were obstructed in 7 patients.On Iohexol HSG,73 tubes were clearly demonstrated in 38 patients.Contrast flow was impeded in 7 tubes of 4 patients. Nine tubes were obstructed in 6 patients.Conclusions Sonovue CEUS is slightly less accurate than Iohexol X-ray HSG.

  5. Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer

    Science.gov (United States)

    2015-10-08

    Anxiety Disorder; Depression; Fatigue; Leydig Cell Tumor; Ovarian Sarcoma; Ovarian Stromal Cancer; Pain; Peritoneal Carcinomatosis; Pseudomyxoma Peritonei; Recurrent Breast Cancer; Recurrent Cervical Cancer; Recurrent Endometrial Carcinoma; Recurrent Fallopian Tube Cancer; Recurrent Gestational Trophoblastic Tumor; Recurrent Ovarian Epithelial Cancer; Recurrent Ovarian Germ Cell Tumor; Recurrent Primary Peritoneal Cavity Cancer; Recurrent Uterine Sarcoma; Recurrent Vaginal Cancer; Recurrent Vulvar Cancer

  6. 输卵管超声造影的临床实践%Clinical Practice in Ultrasonography of Fallopian Tube

    Institute of Scientific and Technical Information of China (English)

    香钰婷; 白文佩

    2016-01-01

    目前,不孕症的发病率越来越高。对于因不孕症就诊的女性,输卵管通畅性检查是必不可少的环节。诊断输卵管通畅性的“金标准”是腹腔镜下美蓝通液术,目前一线检查方法是子宫输卵管造影(HSG)。但腹腔镜下美蓝通液术需住院在全身麻醉下进行,HSG又存在碘过敏、放射线暴露等风险,因此学者们一直致力于研究输卵管超声造影技术。目前常见的输卵管超声造影技术包括盐水灌注超声造影(SIS)、子宫输卵管超声造影(HyCoSy)、子宫输卵管超声泡沫造影(HyFoSy)等,尤其以HyCoSy应用最广。与传统的腹腔镜下美蓝通液术及HSG相比,HyCoSy诊断效果可靠,操作过程简便,耐受性好,又避免了上述缺点,有望成为评估输卵管通畅性的一线方法。%Nowadays, the prevalence of infertility is increasing. For infertile women, it is necessary to assess tubal patency. The gold standard of tubal patency assessment is laparoscopy with chromopertubation (LC). Hysterosalpingography (HSG), the most widely used technique, may cause iodine allergy and radiation exposure. Therefore, ultrasonography is expected as an alternative method of tubal patency assessment. At present, ultrasonography of fallopian tube consists of saline-infusion sonography (SIS), hysterosalpingo-contrast sonography (HyCoSy) and hysterosalpingo-foam sonography (HyFoSy), and HyCoSy is the most commonly used. Compared to traditional LC and HSG, HyCoSy shows accuracy and convenience while avoiding hospitalization, general anesthesia, radiation and iodine allgery, which makes it a promising technique in the future.

  7. 子宫切除后发生输卵管脱垂的危险因素分析%Investigation of fallopian tube prolapse and analysis its risk factors after hysterectomy

    Institute of Scientific and Technical Information of China (English)

    孟凡峰; 张艳霞; 王朝蓉; 严妮子

    2015-01-01

    目的::探讨子宫切除术后输卵管脱垂( FTP)的发生情况及其危险因素。方法:回顾分析2006年1月~2014年3月在陕西中医学院第二附属医院因良性疾病行全子宫切除术的4210例患者的资料,对可能引起术后FTP的相关因素进行单因素分析及Lo-gistic多因素回归分析。结果:4210例患者中,31例(0.74%)发生FTP。单因素分析结果显示,贫血、术中阴道放置引流管、术后2周内重体力活动、术后感染与子宫切除术后FTP的发生相关( P<0.05)。多因素分析结果显示,贫血( OR=3.703,95%CI=1.057~12.981)、术中阴道放置引流管( OR=6.745,95%CI=1.856~24.512)、术后2周内重体力活动( OR=3.809,95%CI=1.125~12.891)是子宫切除术后FTP的危险因素。结论:子宫切除术后FTP的发生与贫血、术中阴道放置引流管、术后2周重体力活动有关。应针对这些危险因素预防这一并发症的发生。%Objective:To investigate the occurrence of fallopian tube prolapse and a-nalysis its risk factors after hysterectomy in our hospital. Methods:A retrospective analysis the information of the number of 4210 patients who underwent hysterectomy Due to the benign dis-eases in our hospital from Jan. 2006 to Mar. 2014,and univariate analysis and multipievariate Logistic regression analysis was used in the factors which may cause fallopian tube prolapse af-ter hysterectomy. Results:4210 clinical cases were involved in the retrospective analysis. 31 (0. 74%)clinical cases developed FTP after hysterectomy. In the univariate analysis,anemia,to place drainage tubes in vaginal,heavy physical activity 2 weeks after operation and infection af-ter operative were related to occurs of FTP postoperative(P<0. 05). In the multiveariate analy-sis,anemia(OR=3. 703,95%CI=1. 057~12. 981),drainage tubes in placed in vaginal (OR=6. 745,95%CI=1. 856~24. 512),heavy physical activity 2 weeks after operation (OR=3. 809,95%CI=1. 125 ~12. 891) were the risk factors of

  8. External Application of Chinese Drugs on Acupoint Shenque Combined with Salpingostomy for Treatment of Sterility Caused by Obstruction of the Fallopian Tube-A Clinical Report of 45 Cases

    Institute of Scientific and Technical Information of China (English)

    Huang Jianmei; Wang Wei

    2005-01-01

    Objective: To observe the therapeutic effect of external application of Chinese drugs on acupoint Shenque (CV 8) combined with salpingostomy for treatment of sterility caused by obstruction of the fallopian tube.Method: 75 cases were randomly divided into the following 2 groups. Forty-five patients in the treatment group were treated with external application of Chinese drugs on acupoint Shenque (CV 8) combined with salpingostomy, while 30 patients in the control group were treated with salpingostomy only. Results: The results showed that in the treatment group, 26 cases were cured, 11 cases improved, and 8 cases failed, with a total effective rate of 82.22%; while in the control group, 14 cases were cured, 7 cases improved, and 9 cases failed, with a total effective rate of 70.00%. There is a significant difference in the total effective rate between the two groups (P<0.05). Conclusion: The therapeutic effect of external application of Chinese drugs on acupoint Shenque combined with salpingostomy is better than that of salpingostomy only.

  9. Wnt-activation down-regulates Olfactomedin-1 (Olfm-1) in Fallopian tubal Epithelial cells: A Microenvironment Predisposed to Tubal Ectopic Pregnancy

    OpenAIRE

    Kodithuwakku, Suranga P; Pang, Ronald T. K.; Ernest H Y Ng; Cheung, Annie N. Y.; Horne, Andrew W.; Ho, Pak-Chung; Yeung, William S. B.; Lee, Kai-Fai

    2011-01-01

    Ectopic pregnancy occurs when the embryo failed to transits to the uterus and attached to the luminal epithelium of Fallopian tube. Tubal ectopic pregnancy (EP) is a common gynecological emergency and more than 95% of EP occurs in the ampullary region of the Fallopian tube (FT). In humans, Wnt-activation and down-regulation of Olfactomedin-1 (Olfm-1) occur in the receptive endometrium and coincided with embryo implantation in vivo. Whether similar molecular changes happen in the Fallopian tub...

  10. Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Bevacizumab in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery or Gynecological Cancers

    Science.gov (United States)

    2016-06-09

    Cervical Adenosarcoma; Cervical Adenosquamous Carcinoma; Cervical Carcinosarcoma; Cervical Squamous Cell Carcinoma; Endometrial Clear Cell Adenocarcinoma; Endometrial Endometrioid Adenocarcinoma; Endometrial Mixed Adenocarcinoma; Endometrial Mucinous Adenocarcinoma; Endometrial Squamous Cell Carcinoma; Endometrial Transitional Cell Carcinoma; Endometrial Undifferentiated Carcinoma; Fallopian Tube Adenocarcinoma; Fallopian Tube Clear Cell Adenocarcinoma; Fallopian Tube Mucinous Adenocarcinoma; Fallopian Tube Serous Adenocarcinoma; Fallopian Tube Transitional Cell Carcinoma; Malignant Ovarian Epithelial Tumor; Malignant Peritoneal Neoplasm; Ovarian Carcinosarcoma; Ovarian Clear Cell Adenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Adenocarcinoma; Ovarian Serous Adenocarcinoma; Ovarian Transitional Cell Carcinoma; Primary Peritoneal Serous Adenocarcinoma; Recurrent Fallopian Tube Carcinoma; Recurrent Melanoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Stage IV Skin Melanoma; Undifferentiated Fallopian Tube Carcinoma; Undifferentiated Ovarian Carcinoma; Uterine Corpus Carcinosarcoma

  11. The clinical implications of new insights into the origins of epithelial ovarian cancer with emphasis on the British Columbia Ovarian Cancer Prevention Initiative

    Directory of Open Access Journals (Sweden)

    Dianne Miller

    2016-01-01

    Full Text Available In the last ten years our understanding of the origin of epithelial ovarian cancer has changed. This includes the realization that the majority of High Grade serous cancers originate in fallopian tube epithelium and the majority of endometroid and clear cell cancer arise in foci of endometriosis. These new insights have profound implications of both prevention and treatment.

  12. The Diagnostic and Therapeutic Value of Selective Hysterosalpingography and Fallopian Tube Recanalization in Female Infertility Caused by Salpingemphraxis%选择性子宫输卵管造影与再通术对阻塞性不孕的诊疗价值

    Institute of Scientific and Technical Information of China (English)

    曾良成

    2011-01-01

    目的 探讨选择性子宫输卵管造影与再通术对输卵管阻塞所致不孕的诊疗价值.资料与方法 回顾性分析200例女性不孕症患者,年龄20~42岁,平均不孕年限为3.8年,均行选择性子宫输卵管造影与再通术后跟踪观察1年,观察诊疗效果.结果 200例396条输卵管中294条显示不同程度的阻塞,再通成功212条,再通成功率为81.2%,126例患者双侧或单侧再通成功,1年内成功正常受孕46例,占再通成功病例的36.5%.结论 选择性子宫输卵管造影对输卵管阻塞所致不孕症具有较高的诊断价值,再通术对输卵管阻塞所致不孕症有一定的治疗价值.%Purpose To discuss the diagnostic and therapeutic value of selective hysterosalpingography and fallopian tube recanalization in female infertility caused by salpingemphraxis. Materials and Methods Hysterosalpingography and fallopiantube recanalization operation was performed on a total of 200 female infertility patients, whose ages ranged from 20 to 42 with an average of 3.8 years' infertility. These patients were followed for one year to observe the diagnostic and therapeutic outcome. Results Among the 396 fallopian tubes in 200 female infertility patients, 294 were obstructed in different degrees and 212 recanalization was achieved with success rate of 81.2%. Double or single fallopian tube recanalization was achieved in 126 patients, among whom 46 conceived within 1 year, with a conception rate of 36.5%. Conclusion Selective hysterosalpingography has great diagnostic value in female infertility caused by salpingemphraxis and fallopian tube recanalization operation shows therapeutic value.

  13. Quality of pathology reports for advanced ovarian cancer

    DEFF Research Database (Denmark)

    Verleye, Leen; Ottevanger, Petronella B; Kristensen, Gunnar B;

    2011-01-01

    To assess the quality of surgical pathology reports of advanced stage ovarian, fallopian tube and primary peritoneal cancer. This quality assurance project was performed within the EORTC-GCG 55971/NCIC-CTG OV13 study comparing primary debulking surgery followed by chemotherapy with neoadjuvant ch...

  14. Quality of pathology reports for advanced ovarian cancer

    DEFF Research Database (Denmark)

    Verleye, Leen; Ottevanger, Petronella B; Kristensen, Gunnar B;

    2011-01-01

    To assess the quality of surgical pathology reports of advanced stage ovarian, fallopian tube and primary peritoneal cancer. This quality assurance project was performed within the EORTC-GCG 55971/NCIC-CTG OV13 study comparing primary debulking surgery followed by chemotherapy with neoadjuvant...

  15. Clinical analysis of 129 infertility patients with both fallopian tubes unobstructed and cavitas pelvis fluidify%129例双侧输卵管通畅伴盆腔积液不孕患者的临床分析

    Institute of Scientific and Technical Information of China (English)

    梁雪飞; 王书佳; 柳雪琴

    2010-01-01

    目的 探讨盆腔积液与不孕的关系.方法 回顾性分析阴道超声提示盆腔积液而子宫输卵管造影提示双侧输卵管通畅的129例不孕患者的临床资料.经中药治疗3个月后,盆腔积液消失86例,盆腔积液不消失43例,对两者妊娠率进行比较.结果 盆腔积液消失患者妊娠率为30.23%(26/86),盆腔积液不消失患者妊娠率为6.98%(3/43),两者妊娠率比较差异有统计学意义(P<0.05).未妊娠患者中87例行腹腔镜检查,其中55例为子宫内膜异位症,25例因慢性盆腔炎性疾病引起不同程度的盆腔粘连,1例大量盆腔积液为腹膜结核,6例仅见淡红色盆腔积液而未发现其他异常.31例患者腹腔镜检查术后通过体外受精-胚胎移植获得妊娠.结论 盆腔积液在不孕中有重要临床意义,应积极寻找原因并治疗,以使患者得到有效治疗.%Objective To evaluate the relationship between cavitas pelvis fluidify and infertility.Methods The clinical data of 129 infertility patients which ultrasound hint cavitas pelvis fluidify but hysterosalpingography hint both fallopian tubes to be unobstructed were analyzed retrospectively. The patients were divided into two groups, after 3 months cure with traditional Chinese medicine, the cavitas pelvis fluidify of 86 cases were obsolescent as group Ⅰ , the cavitas pelvis fluidify of 43 cases were no obsolescent as group Ⅱ. Compared their pregnancy rates. Results The pregnancy rate of group Ⅰ was 30.23%(26/86),group Ⅱ was 6.98%(3/43 ), there was significant deviation between the two groups (P < 0.05 ). Eighty-seven patients who were no pregnant were diagnosed laparoscopy, there were 55 cases with endometriosis (EMS), 25 cases with cavitas pelvis accretion, 1 case with tuberculosis of peritoneum, 6 cases with carmoisine cavitas pelvis fluidify without other abnormal. Thirty-one of these patients were pregnant through in vitro fertilization and embryo transfer. Conclusion Cavitas pelvis

  16. Gastric tube perforation after esophagectomy for esophageal cancer.

    Science.gov (United States)

    Ubukata, Hideyuki; Nakachi, Takeshi; Tabuchi, Takanobu; Nagata, Hiroyuki; Takemura, Akira; Shimazaki, Jiro; Konishi, Satoru; Tabuchi, Takafumi

    2011-05-01

    We searched for cases of perforation of the gastric tube after esophagectomy for esophageal cancer by reviewing the literature. Only 13 cases were found in the English literature, and serious complications were seen in all cases, especially in cases of posterior mediastinal reconstruction. However, in the Japanese literature serious complications were also frequently seen in retrosternal reconstruction. Gastric tubes are at a higher risk of developing an ulcer than the normal stomach, including an ulcer due to Helicobacter pylori infection, insufficient blood supply, gastric stasis, and bile juice regurgitation. H. pylori eradication and acid-suppressive medications are important preventive therapies for ordinary gastric ulcers, but for gastric tube ulcers the effects of such treatments are still controversial. We tried to determine the most appropriate treatment to avoid serious complications in the gastric tubes, but we could not confirm an optimal route because each had advantages and disadvantages. However, at least in cases with severe atrophic gastritis due to H. pylori infection or a history of frequent peptic ulcer treatment, the antesternal route is clearly the best. Many cases of gastric tube ulcers involve no pain, and vagotomy may be one of the reasons for this absence of pain. Therefore, periodic endoscopic examination may be necessary to rule out the presence of an ulcer.

  17. Three-photon imaging of ovarian cancer

    Science.gov (United States)

    Barton, Jennifer K.; Amirsolaimani, Babak; Rice, Photini; Hatch, Kenneth; Kieu, Khanh

    2016-02-01

    Optical imaging methods have the potential to detect ovarian cancer at an early, curable stage. Optical imaging has the disadvantage that high resolution techniques require access to the tissue of interest, but miniature endoscopes that traverse the natural orifice of the reproductive tract, or access the ovaries and fallopian tubes through a small incision in the vagina wall, can provide a minimally-invasive solution. We have imaged both rodent and human ovaries and fallopian tubes with a variety of endoscope-compatible modalities. The recent development of fiber-coupled femtosecond lasers will enable endoscopic multiphoton microscopy (MPM). We demonstrated two- and three-photon excited fluorescence (2PEF, 3PEF), and second- and third-harmonic generation microscopy (SHG, THG) in human ovarian and fallopian tube tissue. A study was undertaken to understand the mechanisms of contrast in these images. Six patients (normal, cystadenoma, and ovarian adenocarcinoma) provided ovarian and fallopian tube biopsies. The tissue was imaged with three-dimensional optical coherence tomography, multiphoton microscopy, and frozen for histological sectioning. Tissue sections were stained with hematoxylin and eosin, Masson's trichrome, and Sudan black. Approximately 1 μm resolution images were obtained with an excitation source at 1550 nm. 2PEF signal was absent. SHG signal was mainly from collagen. 3PEF and THG signal came from a variety of sources, including a strong signal from fatty connective tissue and red blood cells. Adenocarcinoma was characterized by loss of SHG signal, whereas cystic abnormalities showed strong SHG. There was limited overlap of two- and three- photon signals, suggesting that three-photon imaging can provide additional information for early diagnosis of ovarian cancer.

  18. BRCA and early events in the development of high grade serous ovarian cancer

    Directory of Open Access Journals (Sweden)

    Sophia HL George

    2014-01-01

    Full Text Available Women who have an inherited mutation in the BRCA1 or BRCA2 genes have a substantial increased lifetime risk of developing epithelial ovarian cancer, and epidemiological factors related to parity, ovulation and hormone regulation have a dramatic effect on the risk in both BRCA mutation carriers and non-carriers. The most common and most aggressive histotype of epithelial ovarian cancer, high-grade serous carcinoma, is also the histotype associated with germline BRCA mutations. In recent years, evidence has emerged indicating that the likely tissue of origin of high-grade serous carcinoma is the fallopian tube. We have reviewed what is known about the fallopian tube in BRCA mutation carriers at both the transcriptional and translational aspect of their biology. We propose that changes of the transcriptome in BRCA heterozygotes reflect an altered response to the ovulatory stresses from microenvironment, which may include the post-ovulation inflammatory response and altered reproductive hormone physiology.

  19. Active and passive smoking and risk of ovarian cancer.

    OpenAIRE

    Baker, J. A.; Odunuga, O. O.; Rodabaugh, K J; Reid, M.E.; Menezes, R. J.; Moysich, K B

    2009-01-01

    Cancer epidemiologyCancer type:ovarian cancerStudy design:case-controlStudy size:434 cases, 868 controlsDescription of cohort(s) studied:434 women with promary epithelial ovarian, peritoneal, fallopian tube cancer, 868 women randomly selectedExposure(s) evaluated:ETSConfounders controlled for:smoking habitsImpact on risk: nonsmokers with ETS EXPOSURE, OR 0.68, 95%CI 0.47-0.99Current smokers with ETS exposure, OR 0.5, 95% CI 0.34-0.9Never smokres with ETS exposure, OR 0.39, 95% CI 0.1-1.48, P=...

  20. STUDIES ON HUMAN FALLOPIAN TUBAL EPITHELIUM IN DIFFERENT AGE GROUPS

    Directory of Open Access Journals (Sweden)

    Jayasri

    2016-02-01

    Full Text Available BACKGROUND AND AIMS The “fallopian tubes” (oviducts or uterine tubes are long paired flexuous reproductive organ which transports ova, spermatozoa, zygotes, the pre-implantation morulae and blastocyst. It has major role during reproductive period, but it remains as if vestigial organ before puberty and after menopause. Due to increasing rate of tubal block and infertility, oviducts and their structures gaining importance and have become a subject of research in present days particularly epithelium. The aim of the study is to ascertain any histological difference of tubal epithelium in different age groups and the research work could be utilized for investigation and management of infertility. MATERIALS AND METHODS Seven samples of each group i.e., prereproductive, reproductive & postmenopausal were collected from fresh unembalmed human cadavers received in the department of Anatomy, FAA Medical College, Barpeta, Assam. The slides were prepared using the standard laboratory procedure. Under low and high power objectives the type of cells were observed and epithelial height was measured in the different segments. Stress was given for any significant difference of epithelial height between the different age groups. RESULTS Study revealed that among the groups within the same segment, epithelial height was recorded highest (33.57µm in reproductive group as against the lowest (22.91µm in post-menopausal group. Epithelial structures of the prereproductive and reproductive groups were significantly differed (p<0.01 from the postmenopausal group. CONCLUSIONS From the findings of the present study it can be concluded that: 1. In all the groups fallopian tubal epithelium is of simple columnar type and contains three types of cells. Cells are ciliated, secretory & peg (intercalary cells. 2. In all the groups same type of increasing trend of epithelial height from intramural segment to ampullary segment was recorded. 3. In intergroup comparison of

  1. Ovarian cancer risk factors by tumor dominance, a surrogate for cell of origin

    OpenAIRE

    Kotsopoulos, Joanne; Terry, Kathryn Lynne; Poole, Elizabeth M.; Rosner, Bernard Alfred; Murphy, Megan A.; Hecht, Jonathan Lewis; Crum, Christopher Paul; Missmer, Stacey Ann; Cramer, Daniel William; Tworoger, Shelley Slate

    2013-01-01

    Differentiating ovarian tumors based on developmental pathway may further our understanding of the disease. Traditionally, ovarian cancers were thought to arise from the ovarian surface epithelium; however, recent evidence suggests some tumors originate in the fallopian tube. We classified cases in a population-based case-control study (NECC) and two cohort studies (NHS/NHSII) by tumor dominance, a proxy for tissue of origin. Dominant tumors (likely ovarian origin) are restricted to one ovary...

  2. Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer

    DEFF Research Database (Denmark)

    Sabbatini, Paul J; Ragupathi, Govind; Hood, Chandra;

    2007-01-01

    in two patients), fever, myalgia, and localized injection site reactions were most frequent. No clinically relevant hematologic abnormalities were noted. No clinical or laboratory evidence of autoimmunity was seen. Serologic responses by ELISA were largely IgM against each antigen with the exception...

  3. Cancer Survivorship in the Age of YouTube and Social Media: A Narrative Analysis

    OpenAIRE

    Chou, Wen-Ying Sylvia; Hunt, Yvonne; Folkers, Anna; Augustson, Erik

    2011-01-01

    Background As evidenced by the increasing popularity of YouTube (www.youtube.com), personal narratives shared through social media are an area of rapid development in communication among cancer survivors. Identifying the thematic and linguistic characteristics of YouTube cancer stories can provide a better understanding of this naturally occurring communication channel and inform social media communication efforts aiming to use personal stories to reach individuals with serious illnesses. Obj...

  4. Torsion of the fallopian the mimicking appendicitis in a pregnant woman; Torsion de la trompa de Falopio en una mujer gestante simulando apendicitis

    Energy Technology Data Exchange (ETDEWEB)

    Tapia-Vine, M.; Pedrosa, I.; Escribano, N. [Hospital Clinico San Carlos (Spain)

    2000-07-01

    Isolated torsion of the fallopian tube is an uncommon entity. Given the difficulties involved in the preoperative diagnosis, the ultrasound findings characteristic of this anomaly are not widely known. We present a case of tubal torsion associated with a cyst, describing the ultrasound images in our case and those reported in the literature. (Author) 18 refs.

  5. Spontaneous transformation of murine oviductal epithelial cells: A model system to investigate the onset of fallopian-derived tumors

    Directory of Open Access Journals (Sweden)

    MIchael P. Endsley

    2015-07-01

    Full Text Available High-grade serous carcinoma (HGSC is the most lethal ovarian cancer histotype. The fallopian tube secretory epithelial cells (FTSECs are a proposed progenitor cell type. Genetically altered FTSECs form tumors in mice; however, a spontaneous HGSC model has not been described. Apart from a subpopulation of genetically predisposed women, most women develop ovarian cancer spontaneously, which is associated with aging and lifetime ovulations. A murine oviductal cell line (MOELOW was developed and continuously passaged in culture to mimic cellular aging (MOEHIGH. The MOEHIGH cellular model exhibited a loss of acetylated tubulin consistent with an outgrowth of secretory epithelial cells in culture. MOEHIGH cells proliferated significantly faster than MOELOW, and the MOEHIGH cells produced more 2D foci and 3D soft agar colonies as compared to MOELOW. MOEHIGH were xenografted into athymic female nude mice both in the subcutaneous and the intraperiteonal compartments. Only the subcutaneous grafts formed tumors that were negative for cytokeratin, but positive for oviductal markers such as oviductal glycoprotein 1 and Pax8. These tumors were considered to be poorly differentiated carcinoma. The differential molecular profiles between MOEHIGH and MOELOW were determined using RNA-Seq and confirmed by protein expression to uncover pathways important in transformation, like the p53 pathway, the FOXM1 pathway, WNT signaling, and splicing. MOEHIGH had enhanced protein expression of c-myc, Cyclin E, p53 and FOXM1 with reduced expression of p21. MOEHIGH were also less sensitive to cisplatin and DMBA, which induce lesions typically repaired by base-excision repair. A model of spontaneous tumorogenesis was generated starting with normal oviductal cells. Their transition to cancer involved alterations in pathways associated with high-grade serous cancer in humans.

  6. A rare case of fourth consecutive fallopian tube ectopic pregnancy

    Directory of Open Access Journals (Sweden)

    Divya Pandey

    2015-04-01

    Full Text Available We present a case of consecutive fourth tubal ectopic in a patient which was managed by emergency laparotomy and salpingectomy. The first two tubal ectopic pregnancies occurred on the right side while the subsequent two occurred on the contralateral side. The patient was planned for IVF-ET. [Int J Reprod Contracept Obstet Gynecol 2015; 4(2.000: 490-492

  7. Signaling pathways and stem cells in uterus and fallopian tubes

    NARCIS (Netherlands)

    Y. Wang (Yongqian)

    2012-01-01

    textabstractDuring her fertile years, the endometrium of fertile women undergoes regular cycles of regeneration, differentiation and shedding, driven by changing concentrations of the steroid hormones estradiol and progesterone. In the present study, the role of Wnt/β-catenin signaling in relation t

  8. Spatial and Temporal Heterogeneity in High-Grade Serous Ovarian Cancer: A Phylogenetic Analysis

    OpenAIRE

    Roland F Schwarz; Ng, Charlotte K.Y.; Cooke, Susanna L.; Scott Newman; Jillian Temple; Piskorz, Anna M.; Davina Gale; Karen Sayal; Muhammed Murtaza; Baldwin, Peter J.; Nitzan Rosenfeld; Earl, Helena M.; Evis Sala; Mercedes Jimenez-Linan; Parkinson, Christine A.

    2015-01-01

    Editors’ Summary Background Every year, nearly 250,000 women develop ovarian cancer, and about 150,000 die from the disease. Ovarian cancer occurs when a cell on the surface of the ovaries (two small organs in the pelvis that produce eggs) or in the Fallopian tubes (which connect the ovaries to the womb) acquires genetic changes (mutations) that allow it to grow uncontrollably and to spread around the body (metastasize). For women whose ovarian cancer is diagnosed when it is confined to its s...

  9. Analysis of Jugular Foramen Exposure in the Fallopian Bridge Technique

    OpenAIRE

    Satar, Bulent; Yazar, Fatih; Aykut CEYHAN; Arslan, Hasan Huseyin; Aydin, Sedat

    2009-01-01

    Objective: To analyze the exposure of the jugular foramen afforded by the fallopian bridge technique. Method: The jugular foramen exposure was obtained using the jugular foramen approach combined with the fallopian bridge technique. We applied this technique using 10 temporal bone specimens at a tertiary referral center. The exposure was assessed by means of depth of the dissection field and two separate dissection spaces that were created anteriorly and posteriorly to the facial nerve. Anter...

  10. Octreotide in Preventing Diarrhea in Patients Who Are Undergoing Radiation Therapy to the Pelvis

    Science.gov (United States)

    2016-07-12

    Cervical Cancer; Colorectal Cancer; Diarrhea; Endometrial Cancer; Fallopian Tube Cancer; Ovarian Cancer; Prostate Cancer; Sarcoma; Unspecified Adult Solid Tumor, Protocol Specific; Vaginal Cancer; Vulvar Cancer

  11. The use of radiologically placed gastroctomy tubes in head and neck cancer patients receiving radiotherapy

    International Nuclear Information System (INIS)

    Purpose: Patients undergoing radiotherapy to the head and neck area frequently experience radiation reactions that can markedly restrict oral intake, require hospitalization, and occasionally cause treatment interruptions. The Vancouver Cancer Center (VCC) has recently employed radiologically placed gastrostomy tubes (G-tubes) in the management of this problem. A review of the patients on whom this procedure had been performed is the subject of this review. Methods and Materials: Thirty-four patients had gastrostomy tubes inserted under radiologic guidance. This group is compared to a control group matched for age, sex, irradiated volume, and radiation dose, who did not have gastrostomy tubes. Patients with gastrostomy tubes were divided into two categories: (a) patients who had tubes inserted in anticipation of severe reactions, and (b) patients who developed severe radiation reactions necessitating nutritional support. Results: The gastrostomy group consisted of 65% males with an average age of 59 years and stage range of II (12%), III (24%), and IV (65%). In both the elective group and the nonelective group, patients maintained their weight at 95 to 97% of the pretreatment weight, at follow-up of 6 weeks and 3 months. This compared with an average weight loss in the control group of 9% at 6 weeks and 12% at 3 months. The length of hospitalization was a mean of 4.9 days in the elective group and 19 days in the nonelective group. Complication were low compared to those documented in the literature, but included two tube migrations, two aspirations, and one gastrointestinal bleed. Conclusions: We believe that gastrostomy tubes contribute significantly to the management of patients with head and neck cancer, particularly in maintenance of nutrition, and they may decrease the need for hospitalization

  12. Transferrin facilitates the formation of DNA double-strand breaks via transferrin receptor 1: the possible involvement of transferrin in carcinogenesis of high-grade serous ovarian cancer.

    Science.gov (United States)

    Shigeta, S; Toyoshima, M; Kitatani, K; Ishibashi, M; Usui, T; Yaegashi, N

    2016-07-01

    Fallopian tubal epithelium is a candidate for the origin of high-grade serous ovarian cancer. Transferrin-containing follicular fluid and/or retrograde menstrual blood are possible risk factors for carcinogenesis. Accumulation of DNA double-strand breaks (DNA-DSBs) in the fallopian tubal epithelium is considered to play an important role in the development of cancer. However, the mechanisms by which DNA-DSBs accumulate have not yet been fully elucidated. The hydroxyl radical, which is produced in a Fenton reaction catalyzed by an iron ion, serves as a potent DNA-DSB-inducing molecule, raising the potential of an iron ion transporter of transferrin in the formation of DNA-DSBs. We studied the potential involvement of transferrin in DNA damage and the development of ovarian cancer. Treatment with transferrin facilitated the formation of histone 2AX phosphorylated at Serine 139 (γH2AX), which is known as a DNA-DSB marker, in human fallopian tube secretory epithelial cells and A2780 ovarian cancer cells. Knockdown of transferrin receptor 1 (TfR1), but not transferrin receptor 2, suppressed the transferrin uptake and consequent formation of γH2AX. As hydroxyl radicals in reactive oxygen species (ROS) are involved in DNA-DSBs, the formation of ROS was determined. Treatment with TfR1-specific small interference RNAs significantly diminished transferrin-induced formation of ROS. Moreover, TfR1-dependent uptake of transferrin was revealed to augment the formation of DNA-DSBs in the presence of hydrogen peroxide, which served as a substrate for the Fenton reaction. An ex vivo study with murine fallopian tubes further demonstrated that transferrin treatment introduced DNA-DSBs in the fallopian tubal epithelium. Collectively, these data suggested that the transferrin-TfR1 axis accounts for the induction of DNA-DSBs that potentially lead to DNA damage/genome instability. These findings also suggested that exposure to transferrin initiates and promotes the development of

  13. Gynecologic Cancer Information on YouTube: Will Women Watch Advertisements to Learn More?

    Science.gov (United States)

    Cooper, Crystale Purvis; Gelb, Cynthia A; Chu, Jennifer

    2016-09-01

    The quality and accuracy of health content posted on YouTube varies widely. To increase dissemination of evidence-based gynecologic cancer information to US YouTube users, the Centers for Disease Control and Prevention (CDC) sponsored two types of advertisements: (1) pre-roll videos that users had to watch for at least 5 s before seeing a video they selected and (2) keyword-targeted listings that appeared in search results when users entered terms related to gynecologic cancer. From July 2012 to November 2013, pre-roll videos were shown 9.2 million times, viewed (watched longer than the mandatory 5 s) 1.6 million times (17.6 %), and cost $0.09 per view. Keyword-targeted listings were displayed 15.3 million times, viewed (activated by users) 59,766 times (0.4 %), and cost $0.31 per view. CDC videos in advertisements played completely in 17.0 % of pre-roll video views and 44.4 % of keyword-targeted listing views. Advertisements on YouTube can disseminate evidence-based cancer information broadly with minimal cost.

  14. Gynecologic Cancer Information on YouTube: Will Women Watch Advertisements to Learn More?

    Science.gov (United States)

    Cooper, Crystale Purvis; Gelb, Cynthia A; Chu, Jennifer

    2016-09-01

    The quality and accuracy of health content posted on YouTube varies widely. To increase dissemination of evidence-based gynecologic cancer information to US YouTube users, the Centers for Disease Control and Prevention (CDC) sponsored two types of advertisements: (1) pre-roll videos that users had to watch for at least 5 s before seeing a video they selected and (2) keyword-targeted listings that appeared in search results when users entered terms related to gynecologic cancer. From July 2012 to November 2013, pre-roll videos were shown 9.2 million times, viewed (watched longer than the mandatory 5 s) 1.6 million times (17.6 %), and cost $0.09 per view. Keyword-targeted listings were displayed 15.3 million times, viewed (activated by users) 59,766 times (0.4 %), and cost $0.31 per view. CDC videos in advertisements played completely in 17.0 % of pre-roll video views and 44.4 % of keyword-targeted listing views. Advertisements on YouTube can disseminate evidence-based cancer information broadly with minimal cost. PMID:25877466

  15. Gynecologic Cancer Information on YouTube: Will Women Watch Advertisements to Learn More?

    Science.gov (United States)

    Cooper, Crystale Purvis; Chu, Jennifer

    2015-01-01

    The quality and accuracy of health content posted on YouTube varies widely. To increase dissemination of evidence-based gynecologic cancer information to US YouTube users, the Centers for Disease Control and Prevention (CDC) sponsored two types of advertisements: (1) pre-roll videos that users had to watch for at least 5 s before seeing a video they selected and (2) keyword-targeted listings that appeared in search results when users entered terms related to gynecologic cancer. From July 2012 to November 2013, pre-roll videos were shown 9.2 million times, viewed (watched longer than the mandatory 5 s) 1.6 million times (17.6%), and cost $0.09 per view. Keyword-targeted listings were displayed 15.3 million times, viewed (activated by users) 59,766 times (0.4%), and cost $0.31 per view. CDC videos in advertisements played completely in 17.0% of pre-roll video views and 44.4% of keyword-targeted listing views. Advertisements on YouTube can disseminate evidence-based cancer information broadly with minimal cost. PMID:25877466

  16. Ovarian Cancer Pathogenesis: A Model in Evolution

    Directory of Open Access Journals (Sweden)

    Alison M. Karst

    2010-01-01

    Full Text Available Ovarian cancer is a deadly disease for which there is no effective means of early detection. Ovarian carcinomas comprise a diverse group of neoplasms, exhibiting a wide range of morphological characteristics, clinical manifestations, genetic alterations, and tumor behaviors. This high degree of heterogeneity presents a major clinical challenge in both diagnosing and treating ovarian cancer. Furthermore, the early events leading to ovarian carcinoma development are poorly understood, thus complicating efforts to develop screening modalities for this disease. Here, we provide an overview of the current models of ovarian cancer pathogenesis, highlighting recent findings implicating the fallopian tube fimbria as a possible site of origin of ovarian carcinomas. The ovarian cancer model will continue to evolve as we learn more about the genetics and etiology of this disease.

  17. Transuterinal artery interventional therapy for fallopian tubal pregnancy

    International Nuclear Information System (INIS)

    Objective: To study the methods and clinical effect of transuterinal artery interventional therapy of fallopian tubal pregnancy. Methods: The authors cured 34 cases of fallopian tubal pregnancy by interventional methods. In the procedure, 4.1 - 5.0 F catheters were used for performing super selective angiography in uterine artery and then infusing Methotrexate 50-100 mg. Finally gelfoam particles or stripes were used to embolise uterine artery. Before and after the procedure, patients showed changes of clinical symptom, physical signs. Value of urine β-hCG and size of pregnancy cyst were studied. Results: 31 cases were succeeded. The successful rate was 91%. 37 fallopian tubal arteries were displayed in 40 uterine arterial angiographies. The stain of ovary was shown done in 21 cases, the appearance rate was 68%. The stain of pregnant cyst was in six cases, the appearance rate was 18%. Conclusion: It is safe and efficient in performing transuterine artery chemo-embolization for therapy of fallopian tubal pregnancy. It could prevent and control fatal bleeding induced by pregnancy cyst rupture

  18. BRCA1 and BRCA2 Mutations

    Science.gov (United States)

    ... risk of cancer of the ovary , fallopian tube , peritoneum , and pancreas. Men who have a BRCA1 or ... one of the previous criteria? *Cancer of the peritoneum and fallopian tubes should be considered a part ...

  19. EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer

    Science.gov (United States)

    2013-01-15

    Advanced Adult Primary Liver Cancer; Carcinoma of the Appendix; Fallopian Tube Cancer; Gastrointestinal Stromal Tumor; Localized Extrahepatic Bile Duct Cancer; Localized Gallbladder Cancer; Localized Gastrointestinal Carcinoid Tumor; Localized Resectable Adult Primary Liver Cancer; Localized Unresectable Adult Primary Liver Cancer; Metastatic Gastrointestinal Carcinoid Tumor; Ovarian Sarcoma; Ovarian Stromal Cancer; Primary Peritoneal Cavity Cancer; Recurrent Adult Primary Liver Cancer; Recurrent Adult Soft Tissue Sarcoma; Recurrent Colon Cancer; Recurrent Extrahepatic Bile Duct Cancer; Recurrent Gallbladder Cancer; Recurrent Gastric Cancer; Recurrent Gastrointestinal Carcinoid Tumor; Recurrent Non-small Cell Lung Cancer; Recurrent Ovarian Epithelial Cancer; Recurrent Ovarian Germ Cell Tumor; Recurrent Pancreatic Cancer; Recurrent Rectal Cancer; Recurrent Small Intestine Cancer; Recurrent Uterine Sarcoma; Regional Gastrointestinal Carcinoid Tumor; Small Intestine Adenocarcinoma; Small Intestine Leiomyosarcoma; Small Intestine Lymphoma; Stage 0 Non-small Cell Lung Cancer; Stage I Adult Soft Tissue Sarcoma; Stage I Colon Cancer; Stage I Gastric Cancer; Stage I Non-small Cell Lung Cancer; Stage I Ovarian Epithelial Cancer; Stage I Ovarian Germ Cell Tumor; Stage I Pancreatic Cancer; Stage I Rectal Cancer; Stage I Uterine Sarcoma; Stage II Adult Soft Tissue Sarcoma; Stage II Colon Cancer; Stage II Gastric Cancer; Stage II Non-small Cell Lung Cancer; Stage II Ovarian Epithelial Cancer; Stage II Ovarian Germ Cell Tumor; Stage II Pancreatic Cancer; Stage II Rectal Cancer; Stage II Uterine Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage III Colon Cancer; Stage III Gastric Cancer; Stage III Ovarian Epithelial Cancer; Stage III Ovarian Germ Cell Tumor; Stage III Pancreatic Cancer; Stage III Rectal Cancer; Stage III Uterine Sarcoma; Stage IIIA Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Adult Soft Tissue Sarcoma; Stage IV Colon Cancer; Stage

  20. Differential analysis of ovarian and endometrial cancers identifies a methylator phenotype.

    Directory of Open Access Journals (Sweden)

    Diana L Kolbe

    Full Text Available Despite improved outcomes in the past 30 years, less than half of all women diagnosed with epithelial ovarian cancer live five years beyond their diagnosis. Although typically treated as a single disease, epithelial ovarian cancer includes several distinct histological subtypes, such as papillary serous and endometrioid carcinomas. To address whether the morphological differences seen in these carcinomas represent distinct characteristics at the molecular level we analyzed DNA methylation patterns in 11 papillary serous tumors, 9 endometrioid ovarian tumors, 4 normal fallopian tube samples and 6 normal endometrial tissues, plus 8 normal fallopian tube and 4 serous samples from TCGA. For comparison within the endometrioid subtype we added 6 primary uterine endometrioid tumors and 5 endometrioid metastases from uterus to ovary. Data was obtained from 27,578 CpG dinucleotides occurring in or near promoter regions of 14,495 genes. We identified 36 locations with significant increases or decreases in methylation in comparisons of serous tumors and normal fallopian tube samples. Moreover, unsupervised clustering techniques applied to all samples showed three major profiles comprising mostly normal samples, serous tumors, and endometrioid tumors including ovarian, uterine and metastatic origins. The clustering analysis identified 60 differentially methylated sites between the serous group and the normal group. An unrelated set of 25 serous tumors validated the reproducibility of the methylation patterns. In contrast, >1,000 genes were differentially methylated between endometrioid tumors and normal samples. This finding is consistent with a generalized regulatory disruption caused by a methylator phenotype. Through DNA methylation analyses we have identified genes with known roles in ovarian carcinoma etiology, whereas pathway analyses provided biological insight to the role of novel genes. Our finding of differences between serous and endometrioid

  1. Feeding in Oral Cancer Patients After Massive Ablative Surgery: Percutaneous Endoscopic Gastrostomy or Nasogastric Tube.

    Science.gov (United States)

    Tabrizi, Reza; Hosseinpour, Sepanta; Taghizadeh, Fateme

    2016-06-01

    Feeding after ablative oral cancer surgery is a major concern in postoperative care phase. The aim of this study was to compare postoperative phase of healing in patients undergoing nasogastric tube insertion and percutaneous endoscopic gastrostomy. In this single randomized clinical trial, 40 patients were randomly allocated to 2 groups according to a randomized list: group one (20 patients) had nasogastric tube for 4 weeks and group two (20 patients) underwent percutaneous endoscopic gastrostomy for 4 weeks or more after the surgery. Occurrence of infection and wound dehiscence was assessed. Weight loss was defined as reduction in patients' weight at 4 weeks after the surgery compared with preoperation. Weight loss was 7.9 ± 1.91 kg in group one and 5.3 ± 1.38 kg in group two; the difference in this regard between the 2 groups was statistically significant (P = 0.001). In group one, 10 subjects had dehiscence versus 3 subjects in group two; this difference was significant (P = 0.04). Analysis of the data demonstrated a significant difference in postsurgical infection between the 2 groups (P = 0.044). It seems that gastrostomy may be an appropriate method for feeding in patients with extensive oral cancer.

  2. Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status

    Science.gov (United States)

    Coscia, F.; Watters, K. M.; Curtis, M.; Eckert, M. A.; Chiang, C. Y.; Tyanova, S.; Montag, A.; Lastra, R. R.; Lengyel, E.; Mann, M.

    2016-01-01

    A cell line representative of human high-grade serous ovarian cancer (HGSOC) should not only resemble its tumour of origin at the molecular level, but also demonstrate functional utility in pre-clinical investigations. Here, we report the integrated proteomic analysis of 26 ovarian cancer cell lines, HGSOC tumours, immortalized ovarian surface epithelial cells and fallopian tube epithelial cells via a single-run mass spectrometric workflow. The in-depth quantification of >10,000 proteins results in three distinct cell line categories: epithelial (group I), clear cell (group II) and mesenchymal (group III). We identify a 67-protein cell line signature, which separates our entire proteomic data set, as well as a confirmatory publicly available CPTAC/TCGA tumour proteome data set, into a predominantly epithelial and mesenchymal HGSOC tumour cluster. This proteomics-based epithelial/mesenchymal stratification of cell lines and human tumours indicates a possible origin of HGSOC either from the fallopian tube or from the ovarian surface epithelium. PMID:27561551

  3. Interventional therapy of ovarian tube infertility

    International Nuclear Information System (INIS)

    Objective: To evaluate the clinical application of selective salpinography (SSG)and fallopian tube recanalization (FTR). Methods: 215 patients with Infertilis Feminis were performed with hysterosalpinoraphy (HSG)SSG and FRT. Anti-infection and physical therapy were then undertaken postoperatively. Results: The successful rates of properly performed catheterization and recanalization reached 92.8% and 90.2%, respectively. During the follow-up of six years, 98 cases (51.3%)obtained the ability of intrauterine pregnancy. Conclusions: HSG and FTR are simple, reliable, symptomless, very effective for treatment of ovarian tube infertility. (authors)

  4. Prophylactic PEG placement in head and neck cancer:How many feeding tubes are unused (and unnecessary)?

    Institute of Scientific and Technical Information of China (English)

    Mohammad F Madhoun; Matt M Blankenship; Derek M Blankenship; Greg A Krempl; William M Tierney

    2011-01-01

    AIM:To determine the rate of use and non-use of prophylactic percutaneous endoscopic gastrostomy (PEG) tubes among patients with head and neck cancer (HNC) patients.METHODS:All patients with HNC undergoing PEG between January 01,2004 and June 30,2006 were identified. Patients (or their next-of-kin) were surveyed by phone and all available medical records and cancer registry data were reviewed.Prophylactic PEG was defined as placement in the absence of dysphagia and prior to radiation or chemoradiation.Each patient with a prophylactic PEG was assessed for cancer diagnosis,type of therapy,PEG use,and complications related to PEG. RESULTS:One hundred and three patients had PEG tubes placed for HNC.Thirty four patients (33%) could not be contacted for follow-up.Of the 23 (22.3%) patients with prophylactic PEG tubes,11/23 (47.8%) either never used the PEG or used it for less than 2 wk. No association with PEG use vs non-use was observed for cancer diagnosis,stage,or specific cancer treatment. Non-use or limited use was observed in 3/6 (50%) treated with radiation alone vs 8/17 (47.1%) treated with chemoradiation (P = 1.0),and 3 of 10 (30%) treated with surgery vs 8 of 13 (62%) not treated with surgery (P = 0.21).Minor complications were reported in 5/23 (21.7%).One (4.3%) major complication was reported.CONCLUSION:There is a high rate of unnecessary PEG placement when done prophylactically in patients with head and neck cancer.

  5. Randomized study of percutaneous endoscopic gastrostomy versus nasogastric tubes for enteral feeding in head and neck cancer patients treated with (chemo)radiation

    International Nuclear Information System (INIS)

    Full text: Percutaneous endoscopic gastrostomy (PEG) tubes have largely replaced nasogastric tubes (NGT) for nutritional support of patients with head and neck cancer undergoing curative (chemo)radiotherapy without any good scientific basis. A randomized trial was conducted to compare PEG tubes and NGT in terms of nutritional outcomes, complications, patient satisfaction and cost. The study was closed early because of poor accrual, predominantly due to patients' reluctance to be randomized. There were 33 patients eligible for analysis. Nutritional support with both tubes was good. There were no significant differences in overall complication rates, chest infection rates or in patients' assessment of their overall quality of life. The cost of a PEG tube was 10 times that of an NGT. The duration of use of PEG tubes was significantly longer, a median 139 days compared with a median 66 days for NGT. We found no evidence to support the routine use of PEG tubes over NGT in this patient group

  6. Late injury of cancer therapy on the female reproductive tract

    Energy Technology Data Exchange (ETDEWEB)

    Grigsby, P.W. [Washington Univ. School of Medicine, St. FLouis, MO (United States); Russell, A. [Radiological Associates, Sacramento, CA (United States); Bruner, D. [Fox Chase Cancer Center, Philadelphia, PA (United States)] [and others

    1995-03-30

    The purpose of this article is to review the late effects of cancer therapy on the female reproductive tract. The anatomic sites detailed are the vulva, vagina, cervix, uterus, fallopian tubes, and ovaries. The available pathophysiology is discussed. Clinical syndromes are presented. Tolerance doses of irradiation for late effects are rarely presented in the literature and are reviewed where available. Management strategies for surgical, radiotherapeutic, and chemotherapeutic late effects are discussed. Endpoints for evaluation of therapeutic late effects have been formulated utilizing the symptons, objective, management, and analytic (SOMA) format. Late effects on the female reproductive tract from cancer therapy should be recognized and managed appropriately. A grading system for these effects is presented. Endpoints for late effects and tolls for the evaluation need to be further developed. 61 refs., 9 figs., 13 tabs.

  7. Human Leukocyte Antigen-Presented Macrophage Migration Inhibitory Factor Is a Surface Biomarker and Potential Therapeutic Target for Ovarian Cancer.

    Science.gov (United States)

    Patterson, Andrea M; Kaabinejadian, Saghar; McMurtrey, Curtis P; Bardet, Wilfried; Jackson, Ken W; Zuna, Rosemary E; Husain, Sanam; Adams, Gregory P; MacDonald, Glen; Dillon, Rachelle L; Ames, Harold; Buchli, Rico; Hawkins, Oriana E; Weidanz, Jon A; Hildebrand, William H

    2016-02-01

    T cells recognize cancer cells via HLA/peptide complexes, and when disease overtakes these immune mechanisms, immunotherapy can exogenously target these same HLA/peptide surface markers. We previously identified an HLA-A2-presented peptide derived from macrophage migration inhibitory factor (MIF) and generated antibody RL21A against this HLA-A2/MIF complex. The objective of the current study was to assess the potential for targeting the HLA-A2/MIF complex in ovarian cancer. First, MIF peptide FLSELTQQL was eluted from the HLA-A2 of the human cancerous ovarian cell lines SKOV3, A2780, OV90, and FHIOSE118hi and detected by mass spectrometry. By flow cytometry, RL21A was shown to specifically stain these four cell lines in the context of HLA-A2. Next, partially matched HLA-A*02:01+ ovarian cancer (n = 27) and normal fallopian tube (n = 24) tissues were stained with RL21A by immunohistochemistry to assess differential HLA-A2/MIF complex expression. Ovarian tumor tissues revealed significantly increased RL21A staining compared with normal fallopian tube epithelium (P < 0.0001), with minimal staining of normal stroma and blood vessels (P < 0.0001 and P < 0.001 compared with tumor cells) suggesting a therapeutic window. We then demonstrated the anticancer activity of toxin-bound RL21A via the dose-dependent killing of ovarian cancer cells. In summary, MIF-derived peptide FLSELTQQL is HLA-A2-presented and recognized by RL21A on ovarian cancer cell lines and patient tumor tissues, and targeting of this HLA-A2/MIF complex with toxin-bound RL21A can induce ovarian cancer cell death. These results suggest that the HLA-A2/MIF complex should be further explored as a cell-surface target for ovarian cancer immunotherapy.

  8. Analysis of Founder Mutations in Rare Tumors Associated With Hereditary Breast/Ovarian Cancer Reveals a Novel Association of BRCA2 Mutations with Ampulla of Vater Carcinomas.

    Science.gov (United States)

    Pinto, Pedro; Peixoto, Ana; Santos, Catarina; Rocha, Patrícia; Pinto, Carla; Pinheiro, Manuela; Leça, Luís; Martins, Ana Teresa; Ferreira, Verónica; Bartosch, Carla; Teixeira, Manuel R

    2016-01-01

    BRCA1 and BRCA2 mutations are responsible for hereditary breast and ovarian cancer, but they also confer an increased risk for the development of rarer cancers associated with this syndrome, namely, cancer of the pancreas, male breast, peritoneum, and fallopian tube. The objective of this work was to quantify the contribution of the founder mutations BRCA2 c.156_157insAlu and BRCA1 c.3331_3334del for cancer etiology in unselected hospital-based cohorts of Portuguese patients diagnosed with these rarer cancers, by using a strategy that included testing of archival tumor tissue. A total of 102 male breast, 68 pancreatic and 33 peritoneal/fallopian tube carcinoma cases were included in the study. The BRCA2 c.156_157insAlu mutation was observed with a frequency of 7.8% in male breast cancers, 3.0% in peritoneal/fallopian tube cancers, and 1.6% in pancreatic cancers, with estimated total contributions of germline BRCA2 mutations of 14.3%, 5.5%, and 2.8%, respectively. No carriers of the BRCA1 c.3331_3334del mutation were identified. During our study, a patient with an ampulla of Vater carcinoma was incidentally found to carry the BRCA2 c.156_157insAlu mutation, so we decided to test a consecutive series of additional 15 ampullary carcinomas for BRCA1/BRCA2 mutations using a combination of direct founder mutation testing and full gene analysis with next generation sequencing. BRCA2 mutations were observed with a frequency of 14.3% in ampulla of Vater carcinomas. In conclusion, taking into account the implications for both the individuals and their family members, we recommend that patients with these neoplasias should be offered BRCA1/BRCA2 genetic testing and we here show that it is feasible to test for founder mutations in archival tumor tissue. Furthermore, we identified for the first time a high frequency of germline BRCA2 mutations in ampullary cancers. PMID:27532258

  9. Enteral Feeding Tubes in Patients Undergoing Definitive Chemoradiation Therapy for Head-and-Neck Cancer: A Critical Review

    Energy Technology Data Exchange (ETDEWEB)

    Koyfman, Shlomo A., E-mail: koyfmas@ccf.org [Departments of Radiation and Solid Tumor Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Adelstein, David J. [Departments of Radiation and Solid Tumor Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States)

    2012-11-01

    Definitive chemoradiation therapy has evolved as the preferred organ preservation strategy in the treatment of locally advanced head-and-neck cancer (LA-HNC). Dry mouth and dysphagia are among the most common and most debilitating treatment-related toxicities that frequently necessitate the placement of enteral feeding tubes (FT) in these patients to help them meet their nutritional requirements. The use of either a percutaneous endoscopic gastrostomy tube or a nasogastric tube, the choice of using a prophylactic vs a reactive approach, and the effects of FTs on weight loss, hospitalization, quality of life, and long-term functional outcomes are areas of continued controversy. Considerable variations in practice patterns exist in the United States and abroad. This critical review synthesizes the current data for the use of enteral FTs in this patient population and clarifies the relative advantages of different types of FTs and the timing of their use. Recent developments in the biologic understanding and treatment approaches for LA-HNC appear to be favorably impacting the frequency and severity of treatment-related dysphagia and may reduce the need for enteral tube feeding in the future.

  10. Design of 7 MeV drift tube linac as injector of proton accelerator for cancer therapy

    International Nuclear Information System (INIS)

    A 324 MHz drift-tube linac(DTL) is designed for proton cancer therapy. The design demands low power dissipation and short tank. The DTL accelerates beam from 2.5 MeV to 7 MeV, with RF power of 265 kW and total length of 1.9 m. The DTL uses permanent-quadrupole magnet(PQM) inside the drift tubes arranged in an FODO lattice. A new matching method is designed. In stead of the traditional beam transport line, the first four cells in DTL are designed as matching section. It causes the beam ellipse from radio-frequency quadrupole linac(RFQ) to satisfy conditions specified by the DTL periodic structure. The dynamics simulation was performed with PARMILA, and almost no emittance growth has been found. (authors)

  11. Early Rupture of an Ultralow Duodenal Stump after Extended Surgery for Gastric Cancer with Duodenal Invasion Managed by Tube Duodenostomy and Cholangiostomy

    Directory of Open Access Journals (Sweden)

    Konstantinos Blouhos

    2013-01-01

    Full Text Available When dealing with gastric cancer with duodenal invasion, gastrectomy with distal resection of the duodenum is necessary to achieve negative distal margin. However, rupture of an ultralow duodenal stump necessitates advanced surgical skills and close postoperative observation. The present study reports a case of an early duodenal stump rupture after subtotal gastrectomy with resection of the whole first part of the duodenum, complete omentectomy, bursectomy, and D2+ lymphadenectomy performed for a pT3pN2pM1 (+ number 13 lymph nodes adenocarcinoma of the antrum. Duodenal stump rupture was managed successfully by end tube duodenostomy, without omental patching, and tube cholangiostomy. Close assessment of clinical, physical, and radiological signs, output volume, and enzyme concentration of the tube duodenostomy, T-tube, and closed suction drain, which was placed near the tube duodenostomy site to drain the leak around the catheter, dictated postoperative management of the external duodenal fistula.

  12. Results of the combination of open transthoracic esophagectomy with laparoscopic gastric tube formation for esophageal cancer

    NARCIS (Netherlands)

    H.A. Cense; O.R.C. Busch; W.A. Bemelman; H. Obertop; J.J.B. van Lanschot

    2006-01-01

    Background: Postoperative complications after open transthoracic esophagectomy could possibly be reduced if the abdominal phase is performed laparoscopically. The aim of this study was to investigate the feasibility of laparoscopic mobilization of the stomach and gastric tube formation in patients u

  13. Infertility in Women: Hysterosalpingographic Assessment of the Fallopian Tubes in Lagos, Nigeria

    Science.gov (United States)

    Akinola, R. A.; Akinola, O. I.; Fabamwo, A. O.

    2009-01-01

    Tubal disease constitutes a major factor in infertility especially in developing countries. This study was undertaken to assess the hysterosalpingographic patterns seen in infertile patients in an urban centre in Lagos. Two hundred and twenty patients who reported from the gynaecology clinic to the radiology department of Lagos State University…

  14. Transmembrane and truncated (SEC isoforms of MUC1 in the human endometrium and Fallopian tube

    Directory of Open Access Journals (Sweden)

    Wreschner Daniel H

    2003-01-01

    Full Text Available Abstract The cell surface mucin MUC1 is expressed by endometrial epithelial cells with increased abundance in the secretory phase of the menstrual cycle, when it is found both at the apical cell surface and in secretions. This suggests the presence of a maternal cell surface glycoprotein barrier to embryo implantation, arising from the anti-adhesive property of MUC1. In previous work, we demonstrated alternatively spliced MUC1 variant forms in tumour cells. The variant MUC1/SEC lacks the transmembrane and cytoplasmic sequences found in the full-length variant. We now show that MUC1/SEC mRNA is present in endometrial carcinoma cell lines, endometrial tissue and primary cultured endometrial epithelial cells. The protein can be detected using isoform-specific antibodies in uterine flushings, suggesting release from endometrium in vivo. However, on the basis of immunolocalisation studies, MUC1/SEC also remains associated with the apical epithelial surface both in tissue and in cultured cells. Transmembrane MUC1 and MUC1/SEC are both strikingly localised to the apical surface of tubal epithelium. Thus MUC1 may contribute to the anti-adhesive character of the tubal surface, inhibiting ectopic implantation. The mechanism by which this barrier is overcome in endometrium at implantation is the subject of ongoing investigation.

  15. A case of infertility with tuberculosis with multiple calcifications on both fallopian tubes

    OpenAIRE

    Meena Khatri; Preshit Chate

    2013-01-01

    Genital tract tuberculosis usually shows no symptoms and it is diagnosed as such incidentally during infertility investigations. In general, infertility is the most common clinical symptom of pelvic tuberculosis to the extent that it constitutes between 40 to 60 percent of the patients chief complaints. Female genital tuberculosis is still a major cause of infertility in India. This case highlights some of the well known facts about genital tuberculosis, that it is the relatively young female...

  16. Two-dimensional and three-dimensional imaging of uterus and fallopian tubes in female infertility.

    Science.gov (United States)

    Carrascosa, Patricia; Capuñay, Carlos; Vallejos, Javier; Carpio, Jimena; Baronio, Mariano; Papier, Sergio

    2016-06-01

    Noninvasive imaging techniques play an important role in the female infertility diagnostic algorithm. In this review article, a description of the diagnostic performance and potential clinical value of both computerized tomographic virtual hysterosalpingography (CT-VHGS) and magnetic-resonance virtual hysterosalpingography (MR-VHSG) is made, describing for both techniques, to guarantee the best possible diagnostic outcome, patient preparation and normal and principal pathologic findings. Both noninvasive diagnostic imaging modalities improve the diagnostic confidence in identification of the specific cause of female infertility. These procedures are well tolerated and can be performed without tenaculum and sedation. The combined analysis of all the imaging data offers the gynecologist a wide information spectrum, enabling a better therapeutic decision. CT-VHSG and MR-VHSG are consistent diagnostic imaging modalities for the evaluation of the female reproductive system, with an excellent diagnostic performance compared with traditional diagnostic exams and allowing a comprehensive assessment of the female reproductive system. PMID:27140290

  17. Low tube voltage CT for improved detection of pancreatic cancer: detection threshold for small, simulated lesions

    Directory of Open Access Journals (Sweden)

    Holm Jon

    2012-07-01

    Full Text Available Abstract Background Pancreatic ductal adenocarcinoma is associated with dismal prognosis. The detection of small pancreatic tumors which are still resectable is still a challenging problem. The aim of this study was to investigate the effect of decreasing the tube voltage from 120 to 80 kV on the detection of pancreatic tumors. Methods Three scanning protocols was used; one using the standard tube voltage (120 kV and current (160 mA and two using 80 kV but with different tube currents (500 and 675 mA to achieve equivalent dose (15 mGy and noise (15 HU as that of the standard protocol. Tumors were simulated into collected CT phantom images. The attenuation in normal parenchyma at 120 kV was set at 130 HU, as measured previously in clinical examinations, and the tumor attenuation was assumed to differ 20 HU and was set at 110HU. By scanning and measuring of iodine solution with different concentrations the corresponding tumor and parenchyma attenuation at 80 kV was found to be 185 and 219 HU, respectively. To objectively evaluate the differences between the three protocols, a multi-reader multi-case receiver operating characteristic study was conducted, using three readers and 100 cases, each containing 0–3 lesions. Results The highest reader averaged figure-of-merit (FOM was achieved for 80 kV and 675 mA (FOM = 0,850, and the lowest for 120 kV (FOM = 0,709. There was a significant difference between the three protocols (p t-test shows that there was a significant difference between 120 and 80 kV, but not between the two levels of tube currents at 80 kV. Conclusion We conclude that when decreasing the tube voltage there is a significant improvement in tumor conspicuity.

  18. Nasogastric tube feeding in children with cancer: The effect of two different formulas on weight, body composition, and serum protein concentrations

    NARCIS (Netherlands)

    Broeder, den E.; Lippens, L.J.J.; Hof, van 't M.A.; Tolboom, J.J.M.; Sengers, R.C.A.; Berg, van den A.M.J.; Staveren, van W.A.

    2000-01-01

    Background: Treatment of cancer cachexia partly involves the administration of adequate amounts of energy. The aim of this study was to assess the tolerance and efficacy of two equal volumes of tube feeding, one with a standard (1 kcal/mL) and one with a high energy density (1.5 kcal/mL), during the

  19. New models of hematogenous ovarian cancer metastasis demonstrate preferential spread to the ovary and a requirement for the ovary for abdominal dissemination.

    Science.gov (United States)

    Coffman, Lan G; Burgos-Ojeda, Daniela; Wu, Rong; Cho, Kathleen; Bai, Shoumei; Buckanovich, Ronald J

    2016-09-01

    Emerging evidence suggest that many high-grade serous "ovarian" cancers (HGSOC) start in the fallopian tube. Cancer cells are then recruited to the ovary and then spread diffusely through the abdomen. The mechanism of ovarian cancer spread was thought to be largely due to direct shedding of tumor cells into the peritoneal cavity with vascular spread being of limited importance. Recent work challenges this dogma, suggesting hematogenous spread of ovarian cancer may play a larger role in ovarian cancer cell metastasis than previously thought. One reason the role of vascular spread of ovarian cancer has not been fully elucidated is the lack of easily accessible models of vascular ovarian cancer metastasis. Here, we present 3 metastatic models of ovarian cancer which confirm the ability of ovarian cancer to hematogenously spread. Strikingly, we observe a high rate of metastasis to the ovary with the development of ascites in these models. Interestingly, oophorectomy resulted in a complete loss of peritoneal metastases and ascites. Taken together, our data indicate that hematogenously disseminated HGSOC cells have a unique tropism for the ovary and that hematogenous spread in ovarian cancer may be more common than appreciated. Furthermore, our studies support a critical role for the ovary in promoting HGSOC cell metastasis to the abdomen. The models developed here represent important new tools to evaluate both the mechanism of cancer cell recruitment to the ovary and understand and target key steps in ovarian cancer metastasis. PMID:27083386

  20. New models of hematogenous ovarian cancer metastasis demonstrate preferential spread to the ovary and a requirement for the ovary for abdominal dissemination.

    Science.gov (United States)

    Coffman, Lan G; Burgos-Ojeda, Daniela; Wu, Rong; Cho, Kathleen; Bai, Shoumei; Buckanovich, Ronald J

    2016-09-01

    Emerging evidence suggest that many high-grade serous "ovarian" cancers (HGSOC) start in the fallopian tube. Cancer cells are then recruited to the ovary and then spread diffusely through the abdomen. The mechanism of ovarian cancer spread was thought to be largely due to direct shedding of tumor cells into the peritoneal cavity with vascular spread being of limited importance. Recent work challenges this dogma, suggesting hematogenous spread of ovarian cancer may play a larger role in ovarian cancer cell metastasis than previously thought. One reason the role of vascular spread of ovarian cancer has not been fully elucidated is the lack of easily accessible models of vascular ovarian cancer metastasis. Here, we present 3 metastatic models of ovarian cancer which confirm the ability of ovarian cancer to hematogenously spread. Strikingly, we observe a high rate of metastasis to the ovary with the development of ascites in these models. Interestingly, oophorectomy resulted in a complete loss of peritoneal metastases and ascites. Taken together, our data indicate that hematogenously disseminated HGSOC cells have a unique tropism for the ovary and that hematogenous spread in ovarian cancer may be more common than appreciated. Furthermore, our studies support a critical role for the ovary in promoting HGSOC cell metastasis to the abdomen. The models developed here represent important new tools to evaluate both the mechanism of cancer cell recruitment to the ovary and understand and target key steps in ovarian cancer metastasis.

  1. [Role of transanal drainage tube in the prevention of anastomotic leakage after anterior resection for rectal cancer].

    Science.gov (United States)

    Zhao, Song; Tong, Weidong

    2016-06-01

    Anastomotic leakage (AL) is one of the most serious complications of anterior resection for rectal cancer with morbidity about 10%. Distance of anastomosis to anal margin, underlying disease, surgical technique and perioperative situations are associated with AL. The transanal drainage tube (TDT) after anastomosis is gradually proved to be useful in prevention of AL. Most of the literatures suggest that TDT is simple and safe, and can reduce the incidence of AL. The materials and the operating process of TDT have been universalized gradually: application of silicone or rubber material, large lumen with several side holes, placement at a distance of 3 to 5 cm above the anastomosis for 5 to 7 days. However, selection bias existed in previous studies, and the main problems were disunity of enrolling standard and exclusion of patients with high AL risk, which would not fully reflect the value of TDT. Defunctioning stoma (or diverting stoma, DS) is a common method to prevent and treat the AL. At present, efficacy comparison between TDT and DS remains controversial. Thus, randomized, double-blind, controlled trials are needed to investigate the value of TDT in prevention of AL after anterior resection, especially for middle and low rectal cancer. PMID:27353109

  2. Serial Patterns of Ovarian Cancer Biomarkers in a Prediagnosis Longitudinal Dataset.

    Science.gov (United States)

    Blyuss, Oleg; Gentry-Maharaj, Alex; Fourkala, Evangelia-Orania; Ryan, Andy; Zaikin, Alexey; Menon, Usha; Jacobs, Ian; Timms, John F

    2015-01-01

    Early detection of ovarian cancer through screening may have impact on mortality from the disease. Approaches based on CA125 cut-off have not been effective. Longitudinal algorithms such as the Risk of Ovarian Cancer Algorithm (ROCA) to interpret CA125 have been shown to have higher sensitivity and specificity than a single cut-off. The aim of this study was to investigate whether other ovarian cancer-related biomarkers, Human Epididymis 4 (HE4), glycodelin, mesothelin, matrix metalloproteinase 7 (MMP7), and cytokeratin 19 fragment (CYFRA 21-1), could improve the performance of CA125 in detecting ovarian cancer earlier. Serum samples (single and serial) predating diagnosis from 47 women taking part in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) who went on to develop primary invasive ovarian, fallopian tube, or peritoneal cancer (index cancer) (170 samples) and 179 matched controls (893 samples) were included in the study. A multiplex immunobased assay platform (Becton Dickinson) allowing simultaneous measurement of the six serum markers was used. The area under the ROC curve for the panel of three biomarkers (CA125, HE4, and glycodelin) was higher than for CA125 alone for all analysed time groups, indicating that these markers can improve on sensitivity of CA125 alone for ovarian cancer detection. PMID:26819954

  3. Serial Patterns of Ovarian Cancer Biomarkers in a Prediagnosis Longitudinal Dataset

    Directory of Open Access Journals (Sweden)

    Oleg Blyuss

    2015-01-01

    Full Text Available Early detection of ovarian cancer through screening may have impact on mortality from the disease. Approaches based on CA125 cut-off have not been effective. Longitudinal algorithms such as the Risk of Ovarian Cancer Algorithm (ROCA to interpret CA125 have been shown to have higher sensitivity and specificity than a single cut-off. The aim of this study was to investigate whether other ovarian cancer-related biomarkers, Human Epididymis 4 (HE4, glycodelin, mesothelin, matrix metalloproteinase 7 (MMP7, and cytokeratin 19 fragment (CYFRA 21-1, could improve the performance of CA125 in detecting ovarian cancer earlier. Serum samples (single and serial predating diagnosis from 47 women taking part in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS who went on to develop primary invasive ovarian, fallopian tube, or peritoneal cancer (index cancer (170 samples and 179 matched controls (893 samples were included in the study. A multiplex immunobased assay platform (Becton Dickinson allowing simultaneous measurement of the six serum markers was used. The area under the ROC curve for the panel of three biomarkers (CA125, HE4, and glycodelin was higher than for CA125 alone for all analysed time groups, indicating that these markers can improve on sensitivity of CA125 alone for ovarian cancer detection.

  4. Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu

    Science.gov (United States)

    2013-02-27

    Advanced Adult Primary Liver Cancer; Anaplastic Thyroid Cancer; Bone Metastases; Carcinoma of the Appendix; Distal Urethral Cancer; Fallopian Tube Cancer; Gastrinoma; Glucagonoma; Inflammatory Breast Cancer; Insulinoma; Liver Metastases; Localized Unresectable Adult Primary Liver Cancer; Lung Metastases; Male Breast Cancer; Malignant Pericardial Effusion; Malignant Pleural Effusion; Metastatic Gastrointestinal Carcinoid Tumor; Metastatic Parathyroid Cancer; Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter; Newly Diagnosed Carcinoma of Unknown Primary; Occult Non-small Cell Lung Cancer; Pancreatic Polypeptide Tumor; Primary Peritoneal Cavity Cancer; Proximal Urethral Cancer; Pulmonary Carcinoid Tumor; Recurrent Adenoid Cystic Carcinoma of the Oral Cavity; Recurrent Adrenocortical Carcinoma; Recurrent Adult Primary Liver Cancer; Recurrent Anal Cancer; Recurrent Bladder Cancer; Recurrent Breast Cancer; Recurrent Carcinoma of Unknown Primary; Recurrent Cervical Cancer; Recurrent Colon Cancer; Recurrent Endometrial Carcinoma; Recurrent Esophageal Cancer; Recurrent Extrahepatic Bile Duct Cancer; Recurrent Gallbladder Cancer; Recurrent Gastric Cancer; Recurrent Gastrointestinal Carcinoid Tumor; Recurrent Islet Cell Carcinoma; Recurrent Malignant Testicular Germ Cell Tumor; Recurrent Mucoepidermoid Carcinoma of the Oral Cavity; Recurrent Non-small Cell Lung Cancer; Recurrent Ovarian Epithelial Cancer; Recurrent Pancreatic Cancer; Recurrent Parathyroid Cancer; Recurrent Prostate Cancer; Recurrent Rectal Cancer; Recurrent Renal Cell Cancer; Recurrent Salivary Gland Cancer; Recurrent Small Intestine Cancer; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Thyroid Cancer; Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter; Recurrent Urethral Cancer; Recurrent Vaginal

  5. Effective Management of an Advanced Gastric Cancer Patient by TS-1 Combined Chemotherapy Using Nasojejunal Tube and Successful Transfer to Home Care after Percutaneous Transesophageal Gastro-tubing (PTEG: A Case Report

    Directory of Open Access Journals (Sweden)

    Miyade,Yoshio

    2010-02-01

    Full Text Available A 67-year-old woman with debilitation and massive ascites was admitted to our hospital and diagnosed with stage IV scirrhous gastric cancer with peritoneal dissemination. After successful nasojejunal tube feeding because of oral intake disability, TS-1 combined with paclitaxel chemotherapy was selected. TS-1 at 80mg/m2 was given daily via nasojejunal tube for 2 weeks, followed by a 1-week rest, and paclitaxel at 50mg/m2 was administered intravenously on day 1 and 8. There were no serious side effects. After 4 cycles, a partial response was observed and percutaneous transesophageal gastro-tubing (PTEG was placed. After the fifth cycle, she was transferred to her home and received chemotherapy in an outpatient clinic. After 7 cycles, the disease progressed, and TS-1 combined with low-dose cisplatin was administered for 3 cycles. However, the patient died 16 weeks after discharge. PTEG was useful not only for a route of TS-1 administration, but also for receiving chemotherapy at home to maintain her quality.

  6. Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progressioan

    International Nuclear Information System (INIS)

    Aldo-keto reductase (AKR) 1C family member 3 (AKR1C3), one of four identified human AKR1C enzymes, catalyzes steroid, prostaglandin, and xenobiotic metabolism. In the prostate, AKR1C3 is up-regulated in localized and advanced prostate adenocarcinoma, and is associated with prostate cancer (PCa) aggressiveness. Here we propose a novel pathological function of AKR1C3 in tumor angiogenesis and its potential role in promoting PCa progression. To recapitulate elevated AKR1C3 expression in cancerous prostate, the human PCa PC-3 cell line was stably transfected with an AKR1C3 expression construct to establish PC3-AKR1C3 transfectants. Microarray and bioinformatics analysis were performed to identify AKR1C3-mediated pathways of activation and their potential biological consequences in PC-3 cells. Western blot analysis, reverse transcription-polymerase chain reaction (RT-PCR), enzyme-linked immunosorbent assay (ELISA), and an in vitro Matrigel angiogenesis assays were applied to validate the pro-angiogenic activity of PC3-AKR1C3 transfectants identified by bioinformatics analysis. Microarray and bioinformatics analysis suggested that overexpression of AKR1C3 in PC-3 cells modulates estrogen and androgen metabolism, activates insulin-like growth factor (IGF)-1 and Akt signaling pathways, as well as promotes tumor angiogenesis and aggressiveness. Levels of IGF-1 receptor (IGF-1R) and Akt activation as well as vascular endothelial growth factor (VEGF) expression and secretion were significantly elevated in PC3-AKR1C3 transfectants in comparison to PC3-mock transfectants. PC3-AKR1C3 transfectants also promoted endothelial cell (EC) tube formation on Matrigel as compared to the AKR1C3-negative parental PC-3 cells and PC3-mock transfectants. Pre-treatment of PC3-AKR1C3 transfectants with a selective IGF-1R kinase inhibitor (AG1024) or a non-selective phosphoinositide 3-kinases (PI3K) inhibitor (LY294002) abolished ability of the cells to promote EC tube formation. Bioinformatics

  7. Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progressioan

    Directory of Open Access Journals (Sweden)

    Davis Jeffrey S

    2010-12-01

    Full Text Available Abstract Background Aldo-keto reductase (AKR 1C family member 3 (AKR1C3, one of four identified human AKR1C enzymes, catalyzes steroid, prostaglandin, and xenobiotic metabolism. In the prostate, AKR1C3 is up-regulated in localized and advanced prostate adenocarcinoma, and is associated with prostate cancer (PCa aggressiveness. Here we propose a novel pathological function of AKR1C3 in tumor angiogenesis and its potential role in promoting PCa progression. Methods To recapitulate elevated AKR1C3 expression in cancerous prostate, the human PCa PC-3 cell line was stably transfected with an AKR1C3 expression construct to establish PC3-AKR1C3 transfectants. Microarray and bioinformatics analysis were performed to identify AKR1C3-mediated pathways of activation and their potential biological consequences in PC-3 cells. Western blot analysis, reverse transcription-polymerase chain reaction (RT-PCR, enzyme-linked immunosorbent assay (ELISA, and an in vitro Matrigel angiogenesis assays were applied to validate the pro-angiogenic activity of PC3-AKR1C3 transfectants identified by bioinformatics analysis. Results Microarray and bioinformatics analysis suggested that overexpression of AKR1C3 in PC-3 cells modulates estrogen and androgen metabolism, activates insulin-like growth factor (IGF-1 and Akt signaling pathways, as well as promotes tumor angiogenesis and aggressiveness. Levels of IGF-1 receptor (IGF-1R and Akt activation as well as vascular endothelial growth factor (VEGF expression and secretion were significantly elevated in PC3-AKR1C3 transfectants in comparison to PC3-mock transfectants. PC3-AKR1C3 transfectants also promoted endothelial cell (EC tube formation on Matrigel as compared to the AKR1C3-negative parental PC-3 cells and PC3-mock transfectants. Pre-treatment of PC3-AKR1C3 transfectants with a selective IGF-1R kinase inhibitor (AG1024 or a non-selective phosphoinositide 3-kinases (PI3K inhibitor (LY294002 abolished ability of the cells

  8. Imaging and PET-CT evaluation of Gi tract cancers; Imagerie et TEP scanner dans les cancers du tube digestif

    Energy Technology Data Exchange (ETDEWEB)

    Laurent, V. [Hopital de Brabois-Vandoeuvre, Service de Radiologie Adultes, 54 - Nancy (France); Olivier, P. [Hopital de Brabois-Vandoeuvre, Service de Medecine Nucleaire, 54 - Nancy (France)

    2008-03-15

    Imaging plays a pivotal role in the management of G.I. tract cancers for diagnosis, characterization, locoregional staging, metastatic work-up and follow-up during and after curative or palliative treatment. The imaging protocols should be optimized and reproducible because of their impact on therapy. Thoracic, abdominal and pelvic CT is the cornerstone of the imaging work-up, optimized and reproducible because of their impact on therapy. Thoracic, abdominal and pelvic CT is the cornerstone of the imaging work-up, optimized and tailored to the specific G.I. segment involved, requiring good G.I. tract distension. Image interpretation of native axial and reformatted multiplanar images is routinely performed. In specific cases, additional targeted imaging with the US or MRI or whole body imaging with PET/CT or MRI may be valuable. PET/CT is a complement to morphological imaging. PET allows detection of lesions otherwise undetected on morphological imaging, usually due to poor contrast with surrounding tissues, and characterization of known lesions. PET/CT is best used as an integral part of a comprehensive imaging work-up. Radiologist and nuclear medicine specialists provide complementary information. each must be familiar with the clinical questions at hand and related stakes, and advantages and limitations of each modality to optimize treatment as part of a multidisciplinary management approach. (authors)

  9. Dermatology on YouTube

    OpenAIRE

    Boyers, Lindsay N.; Quest, Tyler; Karimkhani, Chante; Connett, Jessica; Dellavalle, Robert P.

    2014-01-01

    YouTube, reaches upwards of six billion users on a monthly basis and is a unique source of information distribution and communication. Although the influence of YouTube on personal health decision-making is well established, this study assessed the type of content and viewership on a broad scope of dermatology related content on YouTube. Select terms (i.e. dermatology, sun protection, skin cancer, skin cancer awareness, and skin conditions) were searched on YouTube. Overall, the results inclu...

  10. Expression and function of androgen receptor coactivator p44/Mep50/WDR77 in ovarian cancer.

    Directory of Open Access Journals (Sweden)

    Martin Ligr

    Full Text Available Hormones, including estrogen and progesterone, and their receptors play an important role in the development and progression of ovarian carcinoma. Androgen, its receptor and coactivators have also been implicated in these processes. p44/Mep50/WDR77 was identified as a subunit of the methylosome complex and lately characterized as a steroid receptor coactivator that enhances androgen receptor as well as estrogen receptor-mediated transcriptional activity in a ligand-dependent manner. We previously described distinct expression and function of p44 in prostate, testis, and breast cancers. In this report, we examined the expression and function of p44 in ovarian cancer. In contrast to findings in prostate and testicular cancer and similar to breast cancer, p44 shows strong cytoplasmic localization in morphologically normal ovarian surface and fallopian tube epithelia, while nuclear p44 is observed in invasive ovarian carcinoma. We observed that p44 can serve as a coactivator of both androgen receptor (AR and estrogen receptor (ER in ovarian cells. Further, overexpression of nuclear-localized p44 stimulates proliferation and invasion in ovarian cancer cells in the presence of estrogen or androgen. These findings strongly suggest that p44 plays a role in mediating the effects of hormones during ovarian tumorigenesis.

  11. Overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating chemokine expression

    Science.gov (United States)

    Duckworth, C; Zhang, L; Carroll, S L; Ethier, S P; Cheung, H W

    2016-01-01

    We previously found that the scaffold adapter GRB2-associated binding protein 2 (GAB2) is amplified and overexpressed in a subset of primary high-grade serous ovarian cancers and cell lines. Ovarian cancer cells overexpressing GAB2 are dependent on GAB2 for activation of the phosphatidylinositol 3-kinase (PI3K) pathway and are sensitive to PI3K inhibition. In this study, we show an important role of GAB2 overexpression in promoting tumor angiogenesis by upregulating expression of multiple chemokines. Specifically, we found that suppression of GAB2 by inducible small hairpin RNA in ovarian cancer cells inhibited tumor cell proliferation, angiogenesis and peritoneal tumor growth in immunodeficient mice. Overexpression of GAB2 upregulated the secretion of several chemokines from ovarian cancer cells, including CXCL1, CXCL2 and CXCL8. The secreted chemokines not only signal through endothelial CXCR2 receptor in a paracrine manner to promote endothelial tube formation, but also act as autocrine growth factors for GAB2-induced transformation of fallopian tube secretory epithelial cells and clonogenic growth of ovarian cancer cells overexpressing GAB2. Pharmacological inhibition of inhibitor of nuclear factor kappa-B kinase subunit β (IKKβ), but not PI3K, mechanistic target of rapamycin (mTOR) or mitogen-activated protein kinase (MEK), could effectively suppress GAB2-induced chemokine expression. Inhibition of IKKβ augmented the efficacy of PI3K/mTOR inhibition in suppressing clonogenic growth of ovarian cancer cells with GAB2 overexpression. Taken together, these findings suggest that overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating expression of CXCL1, CXCL2 and CXCL8 that is IKKβ-dependent. Co-targeting IKKβ and PI3K pathways downstream of GAB2 might be a promising therapeutic strategy for ovarian cancer that overexpresses GAB2. PMID:26657155

  12. The prognostic significance of specific HOX gene expression patterns in ovarian cancer.

    Science.gov (United States)

    Kelly, Zoe; Moller-Levet, Carla; McGrath, Sophie; Butler-Manuel, Simon; Kavitha Madhuri, Thumuluru; Kierzek, Andrzej M; Pandha, Hardev; Morgan, Richard; Michael, Agnieszka

    2016-10-01

    HOX genes are vital for all aspects of mammalian growth and differentiation, and their dysregulated expression is related to ovarian carcinogenesis. The aim of the current study was to establish the prognostic value of HOX dysregulation as well as its role in platinum resistance. The potential to target HOX proteins through the HOX/PBX interaction was also explored in the context of platinum resistance. HOX gene expression was determined in ovarian cancer cell lines and primary EOCs by QPCR, and compared to expression in normal ovarian epithelium and fallopian tube tissue samples. Statistical analysis included one-way ANOVA and t-tests, using statistical software R and GraphPad. The analysis identified 36 of the 39 HOX genes as being overexpressed in high grade serous EOC compared to normal tissue. We detected a molecular HOX gene-signature that predicted poor outcome. Overexpression of HOXB4 and HOXB9 was identified in high grade serous cell lines after platinum resistance developed. Targeting the HOX/PBX dimer with the HXR9 peptide enhanced the cytotoxicity of cisplatin in platinum-resistant ovarian cancer. In conclusion, this study has shown the HOX genes are highly dysregulated in ovarian cancer with high expression of HOXA13, B6, C13, D1 and D13 being predictive of poor clinical outcome. Targeting the HOX/PBX dimer in platinum-resistant cancer represents a potentially new therapeutic option that should be further developed and tested in clinical trials. PMID:27225067

  13. Selected ion flow tube-MS analysis of headspace vapor from gastric content for the diagnosis of gastro-esophageal cancer.

    Science.gov (United States)

    Kumar, Sacheen; Huang, Juzheng; Cushnir, Julia R; Španěl, Patrik; Smith, David; Hanna, George B

    2012-11-01

    Gastric content is a complex biofluid within the human stomach which has an important role in digestive processes. It is believed that gastric content may be a contributory factor in the development of upper gastro-intestinal diseases. In this work, selected ion flow tube mass spectrometry (SIFT-MS) has been applied to the quantification of volatile organic compounds (VOCs) in the headspace vapor of gastric content samples, which were retrieved from three groups of patients, including those with gastro-esophageal cancer, noncancer diseases of the upper gastro-intestinal tract, and a healthy cohort. Twelve VOCs have been investigated in this study; the following 7 VOCs, acetone, formaldehyde, acetaldehyde, hexanoic acid, hydrogen sulphide, hydrogen cyanide, and methyl phenol, were found to be significantly different between cancer and healthy groups by the Mann-Whitney U test. Receiver operating characteristics (ROC) analysis was applied for the combined VOCs of acetaldehyde, formaldehyde, hydrogen sulphide, and methyl phenol to discriminate cancer patients from healthy controls. The area under the curve (AUC) was 0.9. This result raises the prospect that a VOC profile rather than a single biomarker may be preferable in the molecular-orientated diagnosis of gastro-oseophageal cancer, and this warrants further investigation to assess its potential application as a new diagnostic test.

  14. Nutritional status and feeding-tube placement in patients with locally advanced hypopharyngeal cancer included in an induction chemotherapy-based larynx preservation program.

    Science.gov (United States)

    Bozec, Alexandre; Benezery, Karen; Chamorey, Emmanuel; Ettaiche, Marc; Vandersteen, Clair; Dassonville, Olivier; Poissonnet, Gilles; Riss, Jean-Christophe; Hannoun-Lévi, Jean-Michel; Chand, Marie-Eve; Leysalle, Axel; Saada, Esma; Sudaka, Anne; Haudebourg, Juliette; Hebert, Christophe; Falewee, Marie-Noelle; Demard, François; Santini, José; Peyrade, Frédéric

    2016-09-01

    The objective of the study is to evaluate the nutritional status and determine its impact on clinical outcomes in patients with locally advanced hypopharyngeal cancer included in an induction chemotherapy (ICT)-based larynx preservation program without prophylactic feeding-tube placement. All patients with locally advanced (T3/4, N0-3, M0) hypopharyngeal squamous cell carcinoma, technically suitable for total pharyngolaryngectomy, treated by docetaxel, cisplatin and 5-fluorouracil (TPF)-ICT for larynx preservation at our institution between 2004 and 2013, were included in this retrospective study. Patients' nutritional status was closely monitored. Enteral nutrition was used if and when a patient was unable to sustain per-oral nutrition and hydration. The impact of nutritional status on clinical outcomes was investigated in univariate and multivariate analysis. A total of 53 patients (42 men and 11 women, mean age = 58.6 ± 8.2 years) were included in this study. Six (11.3 %) patients had lost more than 10 % of their usual body weight before therapy. Compared with patients' usual weight, the mean maximum patient weight loss during therapeutic management was 8.7 ± 4.5 kg. Enteral nutrition was required in 17 patients (32 %). We found no influence of the tested nutritional status-related factors on response to ICT, toxicity of ICT, overall, cause-specific and recurrence-free survival, and on post-therapeutic swallowing outcome. Maximum weight loss was significantly associated with a higher risk of enteral tube feeding during therapy (p = 0.03) and of complications (grade ≥3, p = 0.006) during RT. Without prophylactic feeding-tube placement, approximately one-third of the patients required enteral nutrition. There was no significant impact of nutritional status on oncologic or functional outcomes. PMID:26395117

  15. Nutritional status and feeding-tube placement in patients with locally advanced hypopharyngeal cancer included in an induction chemotherapy-based larynx preservation program.

    Science.gov (United States)

    Bozec, Alexandre; Benezery, Karen; Chamorey, Emmanuel; Ettaiche, Marc; Vandersteen, Clair; Dassonville, Olivier; Poissonnet, Gilles; Riss, Jean-Christophe; Hannoun-Lévi, Jean-Michel; Chand, Marie-Eve; Leysalle, Axel; Saada, Esma; Sudaka, Anne; Haudebourg, Juliette; Hebert, Christophe; Falewee, Marie-Noelle; Demard, François; Santini, José; Peyrade, Frédéric

    2016-09-01

    The objective of the study is to evaluate the nutritional status and determine its impact on clinical outcomes in patients with locally advanced hypopharyngeal cancer included in an induction chemotherapy (ICT)-based larynx preservation program without prophylactic feeding-tube placement. All patients with locally advanced (T3/4, N0-3, M0) hypopharyngeal squamous cell carcinoma, technically suitable for total pharyngolaryngectomy, treated by docetaxel, cisplatin and 5-fluorouracil (TPF)-ICT for larynx preservation at our institution between 2004 and 2013, were included in this retrospective study. Patients' nutritional status was closely monitored. Enteral nutrition was used if and when a patient was unable to sustain per-oral nutrition and hydration. The impact of nutritional status on clinical outcomes was investigated in univariate and multivariate analysis. A total of 53 patients (42 men and 11 women, mean age = 58.6 ± 8.2 years) were included in this study. Six (11.3 %) patients had lost more than 10 % of their usual body weight before therapy. Compared with patients' usual weight, the mean maximum patient weight loss during therapeutic management was 8.7 ± 4.5 kg. Enteral nutrition was required in 17 patients (32 %). We found no influence of the tested nutritional status-related factors on response to ICT, toxicity of ICT, overall, cause-specific and recurrence-free survival, and on post-therapeutic swallowing outcome. Maximum weight loss was significantly associated with a higher risk of enteral tube feeding during therapy (p = 0.03) and of complications (grade ≥3, p = 0.006) during RT. Without prophylactic feeding-tube placement, approximately one-third of the patients required enteral nutrition. There was no significant impact of nutritional status on oncologic or functional outcomes.

  16. Prediction of outcome of tubal ectopic pregnancy on the basis of site of implantation of embryo in the fallopian tube

    Directory of Open Access Journals (Sweden)

    Rajshree D. Katke

    2015-10-01

    Conclusions: Early detection of tubal ectopic and its site of implantation can help in deciding further management especially to go for conservative or surgical management. [Int J Reprod Contracept Obstet Gynecol 2015; 4(5.000: 1431-1435

  17. Morphology of human Fallopian tubes after infection with Mycoplasma genitalium and Mycoplasma hominis - in vitro organ culture study

    DEFF Research Database (Denmark)

    Baczynska, A.; Funch, Peter; Fedder, J.;

    2007-01-01

    against the C-terminal part of the adhesion protein MgPa before infection of HFT organ culture. CONCLUSION: We have shown that the presence of M. genitalium, but not M. hominis, in the HFT organ culture affected the epithelium and resulted in cilia damage. The effect of infection with M. genitalium...

  18. Morphology of human Fallopian tubes after infection with Mycoplasma genitalium and Mycoplasma hominis--in vitro organ culture study

    DEFF Research Database (Denmark)

    Baczynska, Agata; Funch, P; Fedder, J;

    2007-01-01

    against the C-terminal part of the adhesion protein MgPa before infection of HFT organ culture. CONCLUSION: We have shown that the presence of M. genitalium, but not M. hominis, in the HFT organ culture affected the epithelium and resulted in cilia damage. The effect of infection with M. genitalium...

  19. Nasogastric tube syndrome induced by an indwelling long intestinal tube.

    Science.gov (United States)

    Sano, Naoki; Yamamoto, Masayoshi; Nagai, Kentaro; Yamada, Keiichi; Ohkohchi, Nobuhiro

    2016-04-21

    The nasogastric tube (NGT) has become a frequently used device to alleviate gastrointestinal symptoms. Nasogastric tube syndrome (NTS) is an uncommon but potentially life-threatening complication of an indwelling NGT. NTS is characterized by acute upper airway obstruction due to bilateral vocal cord paralysis. We report a case of a 76-year-old man with NTS, induced by an indwelling long intestinal tube. He was admitted to our hospital for treatment of sigmoid colon cancer. He underwent sigmoidectomy to release a bowel obstruction, and had a long intestinal tube inserted to decompress the intestinal tract. He presented acute dyspnea following prolonged intestinal intubation, and bronchoscopy showed bilateral vocal cord paralysis. The NGT was removed immediately, and tracheotomy was performed. The patient was finally discharged in a fully recovered state. NTS be considered in patients complaining of acute upper airway obstruction, not only with a NGT inserted but also with a long intestinal tube. PMID:27099450

  20. Nasogastric tube syndrome induced by an indwelling long intestinal tube.

    Science.gov (United States)

    Sano, Naoki; Yamamoto, Masayoshi; Nagai, Kentaro; Yamada, Keiichi; Ohkohchi, Nobuhiro

    2016-04-21

    The nasogastric tube (NGT) has become a frequently used device to alleviate gastrointestinal symptoms. Nasogastric tube syndrome (NTS) is an uncommon but potentially life-threatening complication of an indwelling NGT. NTS is characterized by acute upper airway obstruction due to bilateral vocal cord paralysis. We report a case of a 76-year-old man with NTS, induced by an indwelling long intestinal tube. He was admitted to our hospital for treatment of sigmoid colon cancer. He underwent sigmoidectomy to release a bowel obstruction, and had a long intestinal tube inserted to decompress the intestinal tract. He presented acute dyspnea following prolonged intestinal intubation, and bronchoscopy showed bilateral vocal cord paralysis. The NGT was removed immediately, and tracheotomy was performed. The patient was finally discharged in a fully recovered state. NTS be considered in patients complaining of acute upper airway obstruction, not only with a NGT inserted but also with a long intestinal tube.

  1. Gastrostomy Tube (G-Tube)

    Science.gov (United States)

    ... endoscope (a thin, flexible tube with a tiny camera and light at the tip) inserted through the ... Nemours Foundation, iStock, Getty Images, Corbis, Veer, Science Photo Library, Science Source Images, Shutterstock, and Clipart.com

  2. Ear tube insertion

    Science.gov (United States)

    Myringotomy; Tympanostomy; Ear tube surgery; Pressure equalization tubes; Ventilating tubes; Ear infection - tubes; Otitis - tubes ... trapped fluid can flow out of the middle ear. This prevents hearing loss and reduces the risk ...

  3. Sub-Thz Vibrational Spectroscopy for Analysis of Ovarian Cancer Cells

    Science.gov (United States)

    Ferrance, Jerome P.; Sizov, Igor; Jazaeri, Amir; Moyer, Aaron; Gelmont, Boris; Globus, Tatiana

    2016-06-01

    Sub-THz vibrational spectroscopy utilizes wavelengths in the submillimeter-wave range ( 1.5-30 wn), beyond those traditionally used for chemical and biomolecular analysis. This low energy radiation excites low-frequency internal molecular motions (vibrations) involving hydrogen bonds and other weak connections within these molecules. The ability of sub-THz spectroscopy to identify and quantify biological molecules is based on detection of signature resonance absorbance at specific frequencies between 0.05 and 1 THz, for each molecule. The long wavelengths of this radiation, mean that it can even pass through entire cells, detecting the combinations of proteins and nucleic acids that exist within the cell. This research introduces a novel sub-THz resonance spectroscopy instrument with spectral resolution sufficient to identify individual resonance absorption peaks, for the analysis of ovarian cancer cells. In vitro cell cultures of SK-OV-3 and ES-2 cells, two human ovarian cancer subtypes, were characterized and compared with a normal non-transformed human fallopian tube epithelial cell line (FT131). A dramatic difference was observed between the THz absorption spectra of the cancer and normal cell sample materials with much higher absorption intensity and a very strong absorption peak at a frequency of 13 wn dominating the cancer sample spectra. Comparison of experimental spectra with molecular dynamic simulated spectroscopic signatures suggests that the high intensity spectral peak could originate from overexpressed mi-RNA molecules specific for ovarian cancer. Ovarian cancer cells are utilized as a proof of concept, but the sub-THz spectroscopy method is very general and could also be applied to other types of cancer.

  4. Ear Tubes

    Science.gov (United States)

    ... of the ear drum or eustachian tube, Down Syndrome, cleft palate, and barotrauma (injury to the middle ear caused by a reduction of air pressure, ... specialist) may be warranted if you or your child has experienced repeated ... fluid in the middle ear, barotrauma, or have an anatomic abnormality that ...

  5. Assessing nodule detection on lung cancer screening CT: the effects of tube current modulation and model observer selection on detectability maps

    Science.gov (United States)

    Hoffman, J. M.; Noo, F.; McMillan, K.; Young, S.; McNitt-Gray, M.

    2016-03-01

    Lung cancer screening using low dose CT has been shown to reduce lung cancer related mortality and been approved for widespread use in the US. These scans keep radiation doses low while maximizing the detection of suspicious lung lesions. Tube current modulation (TCM) is one technique used to optimize dose, however limited work has been done to assess TCM's effect on detection tasks. In this work the effect of TCM on detection is investigated throughout the lung utilizing several different model observers (MO). 131 lung nodules were simulated at 1mm intervals in each lung of the XCAT phantom. A Sensation 64 TCM profile was generated for the XCAT phantom and 2500 noise realizations were created using both TCM and a fixed TC. All nodules and noise realizations were reconstructed for a total of 262 (left and right lungs) nodule reconstructions and 10 000 XCAT lung reconstructions. Single-slice Hotelling (HO) and channelized Hotelling (CHO) observers, as well as a multislice CHO were used to assess area-under-the-curve (AUC) as a function of nodule location in both the fixed TC and TCM cases. As expected with fixed TC, nodule detectability was lowest through the shoulders and leveled off below mid-lung; with TCM, detectability was unexpectedly highest through the shoulders, dropping sharply near the mid-lung and then increasing into the abdomen. Trends were the same for all model observers. These results suggest that TCM could be further optimized for detection and that detectability maps present exciting new opportunities for TCM optimization on a patient-specific level.

  6. Dermatology on YouTube.

    Science.gov (United States)

    Boyers, Lindsay N; Quest, Tyler; Karimkhani, Chante; Connett, Jessica; Dellavalle, Robert P

    2014-06-15

    YouTube, reaches upwards of six billion users on a monthly basis and is a unique source of information distribution and communication. Although the influence of YouTube on personal health decision-making is well established, this study assessed the type of content and viewership on a broad scope of dermatology related content on YouTube. Select terms (i.e. dermatology, sun protection, skin cancer, skin cancer awareness, and skin conditions) were searched on YouTube. Overall, the results included 100 videos with over 47 million viewers. Advocacy was the most prevalent content type at 24% of the total search results. These 100 videos were "shared" a total of 101,173 times and have driven 6,325 subscriptions to distinct YouTube user pages. Of the total videos, 35% were uploaded by or featured an MD/DO/PhD in dermatology or other specialty/field, 2% FNP/PA, 1% RN, and 62% other. As one of the most trafficked global sites on the Internet, YouTube is a valuable resource for dermatologists, physicians in other specialties, and the general public to share their dermatology-related content and gain subscribers. However, challenges of accessing and determining evidence-based data remain an issue.

  7. Neutron tubes

    Science.gov (United States)

    Leung, Ka-Ngo; Lou, Tak Pui; Reijonen, Jani

    2008-03-11

    A neutron tube or generator is based on a RF driven plasma ion source having a quartz or other chamber surrounded by an external RF antenna. A deuterium or mixed deuterium/tritium (or even just a tritium) plasma is generated in the chamber and D or D/T (or T) ions are extracted from the plasma. A neutron generating target is positioned so that the ion beam is incident thereon and loads the target. Incident ions cause D-D or D-T (or T-T) reactions which generate neutrons. Various embodiments differ primarily in size of the chamber and position and shape of the neutron generating target. Some neutron generators are small enough for implantation in the body. The target may be at the end of a catheter-like drift tube. The target may have a tapered or conical surface to increase target surface area.

  8. Straightening tubes

    International Nuclear Information System (INIS)

    Hexagonal wrapper tubes, especially for nuclear reactor core sub-assemblies, may suffer from unacceptable bow as a result of welding wear pads to the wrapper and heat treatment. Straightening of the bow is effected by a method wherein at each of a series of axially spaced locations the faces or vertices of the tube are measured relative to a reference to determine the direction of bow at the locations. From these measurements, the appropriate axial locations for the application of corrective loading can be determined, whereby by application of the loading at a selected face or vertex for such measurements the bow is reduced. Such loading, by an actuator, can be repeated at the locations until the bow is reduced to within tolerances. (author)

  9. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Kidney (Renal Cell) Cancer Leukemia Lung Cancer Lymphoma Pancreatic Cancer Prostate Cancer Skin Cancer Thyroid Cancer Uterine Cancer ... on YouTube. Barbara’s attitude since her diagnosis with pancreatic cancer? No doctor is going to tell her how ...

  10. Nasal Cancer

    Science.gov (United States)

    ... the way to your throat as you breathe. Cancer of the nasal cavity and paranasal sinuses is ... be like those of infections. Doctors diagnose nasal cancer with imaging tests, lighted tube-like instruments that ...

  11. photomultiplier tubes

    CERN Multimedia

    photomultiplier tubes. A device to convert light into an electric signal (the name is often abbreviated to PM). Photomultipliers are used in all detectors based on scintillating material (i.e. based on large numbers of fibres which produce scintillation light at the passage of a charged particle). A photomultiplier consists of 3 main parts: firstly, a photocathode where photons are converted into electrons by the photoelectric effect; secondly, a multiplier chain consisting of a serie of dynodes which multiply the number of electron; finally, an anode, which collects the resulting current.

  12. photomultiplier tube

    CERN Multimedia

    photomultiplier tubes. A device to convert light into an electric signal (the name is often abbreviated to PM). Photomultipliers are used in all detectors based on scintillating material (i.e. based on large numbers of fibres which produce scintillation light at the passage of a charged particle). A photomultiplier consists of 3 main parts: firstly, a photocathode where photons are converted into electrons by the photoelectric effect; secondly, a multiplier chain consisting of a serie of dynodes which multiply the number of electron; finally, an anode, which collects the resulting current.

  13. Tube furnace

    Science.gov (United States)

    Foster, Kenneth G.; Frohwein, Eugene J.; Taylor, Robert W.; Bowen, David W.

    1991-01-01

    A vermiculite insulated tube furnace is heated by a helically-wound resistance wire positioned within a helical groove on the surface of a ceramic cylinder, that in turn is surroundingly disposed about a doubly slotted stainless steel cylindrical liner. For uniform heating, the pitch of the helix is of shorter length over the two end portions of the ceramic cylinder. The furnace is of large volume, provides uniform temperature, offers an extremely precise programmed heating capability, features very rapid cool-down, and has a modest electrical power requirement.

  14. Single-tube-genotyping of gastric cancer related SNPs by directly using whole blood and paper-dried blood as starting materials

    Institute of Scientific and Technical Information of China (English)

    Huan Huang; Ying Bu; Guo-Hua Zhou

    2006-01-01

    AIM: To demonstrate an inexpensive method for typing gastric cancer related single nucleotide polymorphisms (SNPs) using whole blood or paper-dried blood as starting materials.METHODS: PCR amplification is directly carried out from the whole blood or paper-dried blood sample without any DNA extraction step. Before PCR, a blood sample, four primers, and all of biological reagents necessary for PCR were added at a time; After PCR, the amplified products were directly separated by slab gel electrophoresis or microchip CE without any purification. SNP typing was performed by tetra-primer PCR with two inner primers specific to each allele and two outer primers defining the length of allele-specific amplicons. Genotypes were directly discriminated by the size of amplicons specific to each allele, thereby avoiding any post-PCR process.RESULTS: Using a special PCR buffer, inhibitory substances in blood (including the anticoagulant in blood) and filter paper were effectively suppressed;a "true" single-tube-genotyping is thus realized. We successfully determined genotypes IL-1B-511 and IL-1B-31 polymorphisms at the gene IL-1B by using whole-blood and paper-dried blood samples as starting materials respectively. The method is so sensitive that 0.5-1.0 μL of blood sample is enough to give a satisfactory typing results. The genotyping results were confirmed by RFLP-PCR using purified genome DNA,indicating that amplification specificity was not affected by inhibitory components (including coagulants) in blood or filter paper.CONCLUSION: Compared with SNP typing methods based on purified DNA, the proposed method is laborsaving, simple, inexpensive, and less cross-contaminated.It is promising to use this method to type other SNPs.

  15. Effect of the gastric cancer patients without traditional nasogastric tube placement in the elective surgery%择期胃癌手术取消常规留置胃管的效果

    Institute of Scientific and Technical Information of China (English)

    任晖; 季加孚; 杨新颖

    2011-01-01

    目的 探讨择期胃癌手术患者选择性留置胃管的安全性和可行性.方法 对2006年1月至2009年5月期间267例择期胃癌手术患者进行回顾性分析,其中置管组137例,未置管组130例,比较两组患者术后胃肠功能恢复时间、并发症、不适症状、再置胃管率等.结果 两组患者术后胃肠功能恢复的时间、并发症、再置管率,差异无统计学意义(P>0.05);置管组咽部疼痛的发生率和总并发症发生率明显高于未置管组,差异有统计学意义(P<0.01).结论 择期胃癌手术患者取消常规放置胃管在一定程度上促进了患者的康复,并缩短了住院时间,故择期胃癌手术不必要常规留置胃管.%Objective To investigate the safety and validity of the selective nasogastric tube placement in the gastric cancer patients undergoing elective operation by retrospective analysis. Methods A retrospective chart review of 267 patients operated electively for gastric cancer between 2006.1 and 2009.5 was performed at a single institution, tube group (n = 137 ), no tube group (n = 130). The time to recovering gastrointestinal function, nasogastric tube replacement, complications and discomfort were compared between the two groups.Results No significant differences in postoperative gastrointestinal function recovering time, nasogastric tube replacement rates and complications rates were observed between the two groups ( P > 0.05 ), except that throat sere rates were significantly higher in the tube group( P < 0. 01 ). Conclusions Routine prophylactic nasogastric decompression is unnecessary after elective gastrectomy for gastric cancer patients.

  16. A tube-in-tube thermophotovoltaic generator

    Energy Technology Data Exchange (ETDEWEB)

    Ashcroft, J.; Campbell, B.; Depoy, D.

    1996-12-31

    A thermophotovoltaic device includes at least one thermal radiator tube, a cooling tube concentrically disposed within each thermal radiator tube and an array of thermophotovoltaic cells disposed on the exterior surface of the cooling tube. A shell having a first end and a second end surrounds the thermal radiator tube. Inner and outer tubesheets, each having an aperture corresponding to each cooling tube, are located at each end of the shell. The thermal radiator tube extends within the shell between the inner tubesheets. The cooling tube extends within the shell through the corresponding apertures of the two inner tubesheets to the corresponding apertures of the two outer tubesheets. A plurality of the thermal radiator tubes can be arranged in a staggered or an in-line configuration within the shell.

  17. Application of reserved jejunal feeding tube during postoperative chemotherapy of gastric cancer%保留空肠营养管在胃癌术后化疗期间的应用价值

    Institute of Scientific and Technical Information of China (English)

    马汉军; 李三荣; 金汉生; 孙坚; 舒先林; 叶亚林; 吕清泉; 魏琦

    2008-01-01

    Objective To evaluate the effects of reserved jejunal feeding tube during postoperative chemotherapy of gastric cancer. Methods Forty-two patients with gastric cancer underwent radical gastrectomy and going to adjuvant chemotherapy,conventional placed jejunal feeding tube. All of the patients weredivided into group A and group B randomly by pathological staging and tumor site, group A reserved jejunal feeding tube and received enteral nutrition through the tube during chemotherapy, and group B non-reservedjejunal feeding tube and been given daily diet,compared nutrition and immune indicators of two groups beforeand after chemotherapy ,compared the rate of vomiting,and observed complications long-term reserved jejunal feeding tube. Results In post-chemotherapy,nutrition and immune indicators of group A were betterthan those of group B, the difference was statistically significant (P<0.05) ,the rate of vomiting in group Awas significantly lower than that of in group B (X2= 9.75, P<0.01 ), no serious complieations occurred forlong-term reserved jejunal feeding tube. Conclusions Reserved jejunal feeding tube and received enteralnutrition through the tube during postoperative chemotherapy of gastric cancer can significantly improve the nutritional and immune status. It is safe and reliable, worth promoting.%目的 探讨保留空肠营养管在胃癌术后化疗期间的应用价值.方法 总结42例胃癌根治术后行辅助化疗患者的临床资料,术中常规放置空肠营养管,将所有病例按术后病理分期及肿瘤部位随机分为A、B两组,每组各21例,A组保留空肠营养管并在化疗期间经空肠营养管行肠内营养,B组不保留空肠营养管在化疗期间按日常进食,分别比较两组化疗前后营养及免疫指标,比较两组患者呕吐的发生率.观察长期保留空肠营养管的并发症.结果 化疗后A组营养及免疫指标较B组明显提高,两组比较差异有统计学意义(P<0.05).A

  18. The comparative study of nasointestinal tube and nasogastric tubeapplicated in advanced esophagus cancer patients%鼻胃管与鼻肠管应用于晚期食管癌患者的对比研究

    Institute of Scientific and Technical Information of China (English)

    吴志娟; 沈燕; 史屹香; 承雅

    2011-01-01

    目的 探讨在晚期食管癌患者营养支持中应用鼻胃管与螺旋形鼻肠管的护理体会及效果.方法 2008年1月~2011年1月收治的晚期食管癌患者,均给予肠内营养支持治疗,根据给予肠内营养的途径不同分为鼻胃管(16例)和鼻肠管(23例)两组,同时做好置管的各项护理观察和配合,观察两组胃肠道耐受及并发症发生情况,进行比较及分析.结果 两组患者的营养指标较支持前均有明显提高(P<0.05),但两组间比较无显著性差异(P>0.05);置鼻肠管组并发症发生率(尤其是反流、误吸及吸人性肺炎发生率)与置鼻胃管组比较明显降低(P<0.05).结论 在晚期食管癌患者中经鼻胃管和鼻肠管给予肠内营养支持均能满足患者的代谢需要,但经鼻肠管能减少应激性溃疡发生,减轻患者的胃肠不耐受症状,减少反流、误吸及吸人性肺炎等并发症的发生,更为安全、有效.%Objective To evaluate the nursing and effectiveness of nasointestinal tube and nasogastric tube in patients with advanced esophagus cancer. Methods From January 2008 to January 2011, 39 patients suffering from advanced esophagus cancer were given enteral nutritive support. Among them, 16 cases received nasogastric tube, while the other 23 cases received nasointestinal tube. The nasointestinal tube was inserted into the small intestine under fluoroscopic guidance and its tip was placed over the vicinity of ligament of Treitz. The complications and effectiveness of both groups were compared. Results There was an obvious improvement of nutritional status in both groups (P0.05). In the nasointestinal tube group, there was lower complication rate compared with the nasogastric tube group. Conclusion Enteral nutrition by nasointestinal tube or nasogastric tube could meet the needs of advanced esophagus patients, and nutrition by nasointestinal tube could reduce the complications such as stress ulcer, reflux, aspiration pneumonia

  19. 55例肺癌根治术后单根细胸管引流分析%Single fine chest tube drainage after radical surgery of lung cancer:analysis of 55 cases

    Institute of Scientific and Technical Information of China (English)

    宋宣统

    2014-01-01

    目的:探讨肺癌根治术后单根F-28号细胸腔引流管由腋中线第7肋间置入至胸顶引流的可行性。方法观察55例肺叶切除加淋巴结清扫术后病人的引流量、拔管时间及病人对带胸管的耐受性。结果55例中拔管时间没有延长,肺癌术后病人对细胸管胸顶置入耐受良好,未出现因胸管局部疼痛注射杜冷丁和拔管后再穿刺抽胸水病例。结论 F-28号细引流管置入至胸顶引流对于肺癌术后患者是一种安全、可靠、损伤较小的胸管置入方法。%Objective To explore the feasibility of thoracic drainage by using a single fine F-28 style chest tube inserted from the 7th intercostal at axillary line to the chest top after the lobectomy and lymph node dissection of lung cancer .Methods The drainage volume , the time with the chest tube and the tolerance to it were observed in 55 patients after the lobectomy and lymph node dissection of lung cancer .Results In 55 patients, there was no exten-sion of the time with the chest tube and the tolerance to the chest tube was better .There was neither patient who need pethidine injection when chest pain localized and nor patient who need again puncturing for pleural drainage .Conclu-sion The method of thoracic drainage by using one single fine F-28 style chest tube inserted from the 7th intercostal at axillary line to the chest top is a safe , reliable technique with less damage to patients after radical surgery of lung cancer.

  20. Polydopamine/dialdehyde starch/chitosan composite coating for in-tube solid-phase microextraction and in-situ derivation to analysis of two liver cancer biomarkers in human blood.

    Science.gov (United States)

    Wu, Shiju; Cai, Cuicui; Cheng, Jing; Cheng, Min; Zhou, Hongbin; Deng, Jiali

    2016-09-01

    In order to highly enrich two liver cancer biomarkers (hexanal and 2-butanone) in human blood, in this study, natural nontoxic polydopamine/dialdehyde starch/chitosan (PD/DAS/CHI) coating material was synthesized and immobilized on the inner wall of polytetrafluoro-ethlyene (PTFE) tube. It was used to develop the method based on in-tube solid-phase microextraction (IT-SPME) with in-situ derivatization (ISD) coupled to high performance liquid chromatography for the determination of the above mentioned two liver cancer biomarkers in human blood. The simple, rapid and sensitive IT-SPME-ISD method can be finished within 11 min. Under optimum conditions, the limits of detection (LODs) were 1.4 and 1.6 nmol L(-1) for hexanal and 2-butanone, respectively. The relative recoveries from real human blood samples were in the range from 70% to 91% with the intra- and inter-day precisions less than 7.2%. Furthermore, this method was successfully applied for the analysis of hexanal and 2-butanone in blood samples from healthy people with 0.42 ± 0.05 and 0.34 ± 0.04 μmol L(-1), while liver cancer patients with 1.90 ± 0.07  μmol L(-1) and 0.91 ± 0.07 μmol L(-1), respectively. The t-test's results showed there is a statistically significant difference between the data from healthy persons and liver cancer patients. Hence, the developed method might be applied in the screening of suspected liver cancer patients.

  1. Application of enteral nutrition tube for gastrointestinal decompression after surgery in elderly gastric cancer patients%老年胃癌术后应用肠内营养管胃肠减压的临床研究

    Institute of Scientific and Technical Information of China (English)

    尹春柱; 邢宝成; 朱辉; 池昭丞; 孙贺; 陶育纯

    2012-01-01

    目的:探讨老年胃癌患者术后应用肠内营养管胃肠减压的安全性及有效性.方法:选择2007年2月-2010年2月在吉林省肿瘤医院手术治疗的老年胃癌患者66例,随机分为观察组(34例)和对照组(32例),观察组术后应用肠内营养管(复尔凯鼻胃管)胃肠减压,对照组用普通胃管(F16)胃肠减压.观察两组胃管的通畅性,咽喉疼痛,恶心、呕吐,肺部感染,吻合口瘘,切口感染或裂开等不良反应和并发症.结果:观察组和对照组胃管通畅率分别为94.11%和97%(P>0.05);观察组不良反应的发生率(咽喉疼痛8.84%;恶心、呕吐5.88%)低于对照组(咽喉疼痛28.13%;恶心、呕吐25.00%),差异均有统计学意义(均P<0.05);两组间并发症发生率的差异无统计学意义(均P>0.05).结论:老年胃癌患者术后应用肠内营养管胃肠减压可达到胃管减压的相同效果,且不良反应少,利于患者术后康复.%Objective: To investigate the safety and efficacy of using enteral nutrition tube for gastrointestinaldecompression after surgery in elderly gastric cancer patients.Methods: Sixty-six elderly patients with gastric cancer undergoing surgical treatment from February 2007to February 2010 in Jilin Provincal Tumor Hospital were enrolled and the patients were randomly assignedto observation group and control group. After surgery, the patients of the observation group underwentgastrointestinal decompression by using enteral nutrition tube (Flocare nasogastric tube), while those of thecontrol group by using common stomach tube (F16). The tube patency, adverse reactions such as sore throat,nausea and vomiting, and complications such as lung infection, anastomotic leakage and wound infection ordehiscence were observed.Results: The tube patency rates of the observation group and control group were 94.11% and 97%,respectively (P>0.05). The incidences of adverse reactions of the observation group (sore throat was 8.84%; nausea

  2. Titanium condenser tubes

    International Nuclear Information System (INIS)

    The corrosion resistance of titanium in sea water is extremely excellent, but titanium tubes are expensive, and the copper alloy tubes resistant in polluted sea water were developed, therefore they were not used practically. In 1970, ammonia attack was found on the copper alloy tubes in the air-cooled portion of condensers, and titanium tubes have been used as the countermeasure. As the result of the use, the galvanic attack an copper alloy tube plates with titanium tubes as cathode and the hydrogen absorption at titanium tube ends owing to excess electrolytic protection were observed, but the corrosion resistance of titanium tubes was perfect. These problems can be controlled by the application of proper electrolytic protection. The condensers with all titanium tubes adopted recently in USA are intended to realize perfectly no-leak condensers as the countermeasure to the corrosion in steam generators of PWR plants. Regarding large condensers of nowadays, three problems are pointed out, namely the vibration of condenser tubes, the method of joining tubes and tube plates, and the tubes of no coolant leak. These three problems in case of titanium tubes were studied, and the problem of the fouling of tubes was also examined. The intervals of supporting plates for titanium tubes should be narrowed. The joining of titanium tubes and titanium tube plates by welding is feasible and promising. The cleaning with sponge balls is effective to control fouling. (Kako, I.)

  3. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... side effects from the cancer treatments you received. Video Series This video series offers the perspectives of ... care teams (PDF-210KB). Understanding Your Cancer Prognosis Video View this video on YouTube. Three cancer patients ...

  4. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Series This video series offers the perspectives of three cancer patients and their doctor. The videos explain ... Cancer Prognosis Video View this video on YouTube. Three cancer patients and their doctor, Anthony L. Back, ...

  5. 不同胃管固定法对食管癌术后胃管非计划性拔管的影响%Effect of different external nasogastric tube fixations on unplanned nasogastric tube removal after radical esophagectomy for esophageal cancer

    Institute of Scientific and Technical Information of China (English)

    钟就娣; 黄秀英; 王敏; 郑美春

    2013-01-01

    目的:探讨3种不同胃管固定方法对食管癌术后胃管非计划性拔管的影响。方法将234例行食管癌切除术留置胃管的患者,采用随机数字表法分为传统1组74例,传统2组79例,实验组81例。传统1组采用3 M丝绸胶布固定胃管;传统2组采用白扁带系双套结固定胃管;实验组采用“工”字形鼻贴联合活瓣式脸贴固定胃管。观察3组胃管留置过程中胃管发生移位和脱出情况。结果实验组胃管移位和脱管发生率均低于对照1组和2组(均P<0.05);胃管脱出后,传统1组和2组分别有2例和1例发生吻合口瘘,实验组无1例发生吻合口瘘。结论“工”型鼻贴联合活瓣式脸贴固定胃管方法能有效减少非计划性拔管的发生,是一种较好的胃管固定方法,值得临床推广应用。%Objective To investigate the effects of three external nasogastric tube fixations on unplanned nasogastric tube removal after radical esophagectomy for esophageal cancer.Methods Two hundred and thirty four esophageal cancer patients who underwent radical esophagectomy with nasogastric intubation were assigned into conventional group I(n=74),conventional group II (n=79)and experiment group(n=81)using random number table.For external fixation of the nasogastric tube,the traditional group I used“3M”silk tape,the traditional group II used a white flat strap with two knots and the experiment group used an"I"-shaped nasal fixation tape combined with a flapping cheek fixation tape.The three groups were compared in terms of displacement of the indwelling nasogastric tube and slippage of the tube.Results The displacement rate of nasogastric tube and the rate of slippage in the experiment group were both significantly lower than those in both conventional groups I and II(all P<0.05).Conclusion The"I"-shaped nasal fixation tape combined with a flapping cheek fixation tape in fixing the nasogastric tube can effectively reduce the

  6. Pacientes afectos de neoplasia de cabeza-cuello con nutrición enteral domiciliaria por sonda Head and neck cancer patients included at home enteral nutrition by tube

    Directory of Open Access Journals (Sweden)

    I. Cots Seignot

    2009-10-01

    Full Text Available Objetivo: Conocer las características y la evolución de los pacientes diagnosticados de neoplasia de cabeza y cuello (NCC que precisaron recibir tratamiento de radioterapia y que fueron atendidos en un programa de nutrición enteral por sonda a domicilio (NESD. Análisis del peso en función de administrar la nutrición enteral antes o después del inicio de la radioterapia. Material y métodos: Estudio observacional de pacientes con NCC incluidos en el programa de NESD de nuestro hospital durante 2 años. Variables analizadas: sexo, edad, índice de masa corporal (IMC, índice de Karnofsky (IK, motivo del inicio de soporte nutricional, tipo de sonda para la administración de la nutrición, tipo de fórmula nutricional y aporte calórico prescrito, necesidad de cambio de vía y días de NESD. Resultados: Se incluyeron 62 pacientes (77,4% varones y 22,6% hembras con una edad media de 64 años ± 10,1 (rango entre 39 y 90. La disfagia fue el motivo principal de colocación de sonda en estos pacientes. Predominio de sonda nasogástrica (67,7%. La fórmula más utilizada fue la polimérica hipercalórica con un aporte calórico de 1.629 ± 267,09 kcal/día. Globalmente, se observó una pérdida de peso en todos los pacientes durante el período de estudio. Sin embargo, aquellos en los que se inició la NESD antes de la radioterapia el IMC no disminuyó. Conclusión: Los pacientes que iniciaron nutrición por sonda con anterioridad al tratamiento oncológico no perdieron peso durante el periodo de estudio.Objective: To know characteristics and the patients' evolution with head and neck cancer who received radiotherapy treatment and they were included at a home enteral nutrition (HEN by feeding tube programme. To analyse the weight evolution according to the start of HEN before or after radiotherapy. Methods: Observational study of tube feeding patients with head and neck cancer who were included in HEN programme in our hospital for two years

  7. Kidney Cancer

    Science.gov (United States)

    You have two kidneys. They are fist-sized organs on either side of your backbone above your waist. The tubes inside filter and ... blood, taking out waste products and making urine. Kidney cancer forms in the lining of tiny tubes ...

  8. The preclinical natural history of serous ovarian cancer: defining the target for early detection.

    Directory of Open Access Journals (Sweden)

    Patrick O Brown

    2009-07-01

    Full Text Available BACKGROUND: Ovarian cancer kills approximately 15,000 women in the United States every year, and more than 140,000 women worldwide. Most deaths from ovarian cancer are caused by tumors of the serous histological type, which are rarely diagnosed before the cancer has spread. Rational design of a potentially life-saving early detection and intervention strategy requires understanding the lesions we must detect in order to prevent lethal progression. Little is known about the natural history of lethal serous ovarian cancers before they become clinically apparent. We can learn about this occult period by studying the unsuspected serous cancers that are discovered in a small fraction of apparently healthy women who undergo prophylactic bilateral salpingo-oophorectomy (PBSO. METHODS AND FINDINGS: We developed models for the growth, progression, and detection of occult serous cancers on the basis of a comprehensive analysis of published data on serous cancers discovered by PBSO in BRCA1 mutation carriers. Our analysis yielded several critical insights into the early natural history of serous ovarian cancer. First, these cancers spend on average more than 4 y as in situ, stage I, or stage II cancers and approximately 1 y as stage III or IV cancers before they become clinically apparent. Second, for most of the occult period, serous cancers are less than 1 cm in diameter, and not visible on gross examination of the ovaries and Fallopian tubes. Third, the median diameter of a serous ovarian cancer when it progresses to an advanced stage (stage III or IV is about 3 cm. Fourth, to achieve 50% sensitivity in detecting tumors before they advance to stage III, an annual screen would need to detect tumors of 1.3 cm in diameter; 80% detection sensitivity would require detecting tumors less than 0.4 cm in diameter. Fifth, to achieve a 50% reduction in serous ovarian cancer mortality with an annual screen, a test would need to detect tumors of 0.5 cm in diameter

  9. Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells

    Directory of Open Access Journals (Sweden)

    Matyunina Lilya V

    2009-12-01

    Full Text Available Abstract Background Accumulating evidence suggests that somatic stem cells undergo mutagenic transformation into cancer initiating cells. The serous subtype of ovarian adenocarcinoma in humans has been hypothesized to arise from at least two possible classes of progenitor cells: the ovarian surface epithelia (OSE and/or an as yet undefined class of progenitor cells residing in the distal end of the fallopian tube. Methods Comparative gene expression profiling analyses were carried out on OSE removed from the surface of normal human ovaries and ovarian cancer epithelial cells (CEPI isolated by laser capture micro-dissection (LCM from human serous papillary ovarian adenocarcinomas. The results of the gene expression analyses were randomly confirmed in paraffin embedded tissues from ovarian adenocarcinoma of serous subtype and non-neoplastic ovarian tissues using immunohistochemistry. Differentially expressed genes were analyzed using gene ontology, molecular pathway, and gene set enrichment analysis algorithms. Results Consistent with multipotent capacity, genes in pathways previously associated with adult stem cell maintenance are highly expressed in ovarian surface epithelia and are not expressed or expressed at very low levels in serous ovarian adenocarcinoma. Among the over 2000 genes that are significantly differentially expressed, a number of pathways and novel pathway interactions are identified that may contribute to ovarian adenocarcinoma development. Conclusions Our results are consistent with the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as the origin of ovarian adenocarcinoma. While our findings do not rule out the possibility that ovarian cancers may also arise from other sources, they are inconsistent with claims that ovarian surface epithelia cannot serve as the origin of ovarian cancer initiating cells.

  10. Tracheostomy tube - speaking

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000465.htm Tracheostomy tube - speaking To use the sharing features on ... are even speaking devices that can help you. Tracheostomy Tubes and Speaking Air passing through vocal cords ( ...

  11. Neural Tube Defects

    Science.gov (United States)

    Neural tube defects are birth defects of the brain, spine, or spinal cord. They happen in the ... that she is pregnant. The two most common neural tube defects are spina bifida and anencephaly. In ...

  12. Variation in cell signaling protein expression may introduce sampling bias in primary epithelial ovarian cancer.

    Science.gov (United States)

    Mittermeyer, Gabriele; Malinowsky, Katharina; Beese, Christian; Höfler, Heinz; Schmalfeldt, Barbara; Becker, Karl-Friedrich; Avril, Stefanie

    2013-01-01

    Although the expression of cell signaling proteins is used as prognostic and predictive biomarker, variability of protein levels within tumors is not well studied. We assessed intratumoral heterogeneity of protein expression within primary ovarian cancer. Full-length proteins were extracted from 88 formalin-fixed and paraffin-embedded tissue samples of 13 primary high-grade serous ovarian carcinomas with 5-9 samples each. In addition, 14 samples of normal fallopian tube epithelium served as reference. Quantitative reverse phase protein arrays were used to analyze the expression of 36 cell signaling proteins including HER2, EGFR, PI3K/Akt, and angiogenic pathways as well as 15 activated (phosphorylated) proteins. We found considerable intratumoral heterogeneity in the expression of proteins with a mean coefficient of variation of 25% (range 17-53%). The extent of intratumoral heterogeneity differed between proteins (p<0.005). Interestingly, there were no significant differences in the extent of heterogeneity between phosphorylated and non-phosphorylated proteins. In comparison, we assessed the variation of protein levels amongst tumors from different patients, which revealed a similar mean coefficient of variation of 21% (range 12-48%). Based on hierarchical clustering, samples from the same patient clustered more closely together compared to samples from different patients. However, a clear separation of tumor versus normal tissue by clustering was only achieved when mean expression values of all individual samples per tumor were analyzed. While differential expression of some proteins was detected independently of the sampling method used, the majority of proteins only demonstrated differential expression when mean expression values of multiple samples per tumor were analyzed. Our data indicate that assessment of established and novel cell signaling proteins as diagnostic or prognostic markers may require sampling of serous ovarian cancers at several distinct

  13. Variation in cell signaling protein expression may introduce sampling bias in primary epithelial ovarian cancer.

    Directory of Open Access Journals (Sweden)

    Gabriele Mittermeyer

    Full Text Available Although the expression of cell signaling proteins is used as prognostic and predictive biomarker, variability of protein levels within tumors is not well studied. We assessed intratumoral heterogeneity of protein expression within primary ovarian cancer. Full-length proteins were extracted from 88 formalin-fixed and paraffin-embedded tissue samples of 13 primary high-grade serous ovarian carcinomas with 5-9 samples each. In addition, 14 samples of normal fallopian tube epithelium served as reference. Quantitative reverse phase protein arrays were used to analyze the expression of 36 cell signaling proteins including HER2, EGFR, PI3K/Akt, and angiogenic pathways as well as 15 activated (phosphorylated proteins. We found considerable intratumoral heterogeneity in the expression of proteins with a mean coefficient of variation of 25% (range 17-53%. The extent of intratumoral heterogeneity differed between proteins (p<0.005. Interestingly, there were no significant differences in the extent of heterogeneity between phosphorylated and non-phosphorylated proteins. In comparison, we assessed the variation of protein levels amongst tumors from different patients, which revealed a similar mean coefficient of variation of 21% (range 12-48%. Based on hierarchical clustering, samples from the same patient clustered more closely together compared to samples from different patients. However, a clear separation of tumor versus normal tissue by clustering was only achieved when mean expression values of all individual samples per tumor were analyzed. While differential expression of some proteins was detected independently of the sampling method used, the majority of proteins only demonstrated differential expression when mean expression values of multiple samples per tumor were analyzed. Our data indicate that assessment of established and novel cell signaling proteins as diagnostic or prognostic markers may require sampling of serous ovarian cancers at

  14. Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer.

    Science.gov (United States)

    Lawrenson, Kate; Iversen, Edwin S; Tyrer, Jonathan; Weber, Rachel Palmieri; Concannon, Patrick; Hazelett, Dennis J; Li, Qiyuan; Marks, Jeffrey R; Berchuck, Andrew; Lee, Janet M; Aben, Katja K H; Anton-Culver, Hoda; Antonenkova, Natalia; Bandera, Elisa V; Bean, Yukie; Beckmann, Matthias W; Bisogna, Maria; Bjorge, Line; Bogdanova, Natalia; Brinton, Louise A; Brooks-Wilson, Angela; Bruinsma, Fiona; Butzow, Ralf; Campbell, Ian G; Carty, Karen; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Chen, Ann; Chen, Zhihua; Cook, Linda S; Cramer, Daniel W; Cunningham, Julie M; Cybulski, Cezary; Plisiecka-Halasa, Joanna; Dennis, Joe; Dicks, Ed; Doherty, Jennifer A; Dörk, Thilo; du Bois, Andreas; Eccles, Diana; Easton, Douglas T; Edwards, Robert P; Eilber, Ursula; Ekici, Arif B; Fasching, Peter A; Fridley, Brooke L; Gao, Yu-Tang; Gentry-Maharaj, Aleksandra; Giles, Graham G; Glasspool, Rosalind; Goode, Ellen L; Goodman, Marc T; Gronwald, Jacek; Harter, Philipp; Hasmad, Hanis Nazihah; Hein, Alexander; Heitz, Florian; Hildebrandt, Michelle A T; Hillemanns, Peter; Hogdall, Estrid; Hogdall, Claus; Hosono, Satoyo; Jakubowska, Anna; Paul, James; Jensen, Allan; Karlan, Beth Y; Kjaer, Susanne Kruger; Kelemen, Linda E; Kellar, Melissa; Kelley, Joseph L; Kiemeney, Lambertus A; Krakstad, Camilla; Lambrechts, Diether; Lambrechts, Sandrina; Le, Nhu D; Lee, Alice W; Cannioto, Rikki; Leminen, Arto; Lester, Jenny; Levine, Douglas A; Liang, Dong; Lissowska, Jolanta; Lu, Karen; Lubinski, Jan; Lundvall, Lene; Massuger, Leon F A G; Matsuo, Keitaro; McGuire, Valerie; McLaughlin, John R; Nevanlinna, Heli; McNeish, Iain; Menon, Usha; Modugno, Francesmary; Moysich, Kirsten B; Narod, Steven A; Nedergaard, Lotte; Ness, Roberta B; Noor Azmi, Mat Adenan; Odunsi, Kunle; Olson, Sara H; Orlow, Irene; Orsulic, Sandra; Pearce, Celeste L; Pejovic, Tanja; Pelttari, Liisa M; Permuth-Wey, Jennifer; Phelan, Catherine M; Pike, Malcolm C; Poole, Elizabeth M; Ramus, Susan J; Risch, Harvey A; Rosen, Barry; Rossing, Mary Anne; Rothstein, Joseph H; Rudolph, Anja; Runnebaum, Ingo B; Rzepecka, Iwona K; Salvesen, Helga B; Budzilowska, Agnieszka; Sellers, Thomas A; Shu, Xiao-Ou; Shvetsov, Yurii B; Siddiqui, Nadeem; Sieh, Weiva; Song, Honglin; Southey, Melissa C; Sucheston, Lara; Tangen, Ingvild L; Teo, Soo-Hwang; Terry, Kathryn L; Thompson, Pamela J; Timorek, Agnieszka; Tworoger, Shelley S; Van Nieuwenhuysen, Els; Vergote, Ignace; Vierkant, Robert A; Wang-Gohrke, Shan; Walsh, Christine; Wentzensen, Nicolas; Whittemore, Alice S; Wicklund, Kristine G; Wilkens, Lynne R; Woo, Yin-Ling; Wu, Xifeng; Wu, Anna H; Yang, Hannah; Zheng, Wei; Ziogas, Argyrios; Coetzee, Gerhard A; Freedman, Matthew L; Monteiro, Alvaro N A; Moes-Sosnowska, Joanna; Kupryjanczyk, Jolanta; Pharoah, Paul D; Gayther, Simon A; Schildkraut, Joellen M

    2015-11-01

    Genome-wide association studies have identified 20 genomic regions associated with risk of epithelial ovarian cancer (EOC), but many additional risk variants may exist. Here, we evaluated associations between common genetic variants [single nucleotide polymorphisms (SNPs) and indels] in DNA repair genes and EOC risk. We genotyped 2896 common variants at 143 gene loci in DNA samples from 15 397 patients with invasive EOC and controls. We found evidence of associations with EOC risk for variants at FANCA, EXO1, E2F4, E2F2, CREB5 and CHEK2 genes (P ≤ 0.001). The strongest risk association was for CHEK2 SNP rs17507066 with serous EOC (P = 4.74 x 10(-7)). Additional genotyping and imputation of genotypes from the 1000 genomes project identified a slightly more significant association for CHEK2 SNP rs6005807 (r (2) with rs17507066 = 0.84, odds ratio (OR) 1.17, 95% CI 1.11-1.24, P = 1.1×10(-7)). We identified 293 variants in the region with likelihood ratios of less than 1:100 for representing the causal variant. Functional annotation identified 25 candidate SNPs that alter transcription factor binding sites within regulatory elements active in EOC precursor tissues. In The Cancer Genome Atlas dataset, CHEK2 gene expression was significantly higher in primary EOCs compared to normal fallopian tube tissues (P = 3.72×10(-8)). We also identified an association between genotypes of the candidate causal SNP rs12166475 (r (2) = 0.99 with rs6005807) and CHEK2 expression (P = 2.70×10(-8)). These data suggest that common variants at 22q12.1 are associated with risk of serous EOC and CHEK2 as a plausible target susceptibility gene. PMID:26424751

  15. 21 CFR 868.5800 - Tracheostomy tube and tube cuff.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Tracheostomy tube and tube cuff. 868.5800 Section... (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5800 Tracheostomy tube and tube cuff. (a) Identification. A tracheostomy tube and tube cuff is a device intended to be placed into...

  16. 卵巢浆液性肿瘤中输卵管上皮的病理形态学观察%Morphologic changes of fallopian tubal epithelium in ovarian serous tumors

    Institute of Scientific and Technical Information of China (English)

    文佳; 史景丽; 沈丹华; 陈云新; 宋秋静

    2012-01-01

    Objectives To study the morphologic changes of fallopian tubal epithelium in patients with ovarian serous epithelial tumors and to explore the relationship between the tubal epithelial changes and tumorigenesis of serous ovarian carcinoma.Methods The fallopian tubes in 79 cases of high-grade serous ovarian carcinoma,12 cases of low-grade serous ovarian carcinoma,16 cases of serous borderline ovarian tumor and 11 cases of non-ovarian benign tumors were serially examined under light microscope.Immunohistochemical study with EnVision method was used to detect the expression of p53 and bcl-2 protein in the fallopian tubal epithelium in all cases.The occurrences of secretory cell outgrowth(SCOUT),p53 signature,serous tubal intraepithelial carcinoma(STIC) and serous invasive carcinoma were analyzed.Results SCOUT in tubal epithelium was observed in 60.8%(48/79) of the high-grade serous carcinoma group,4/12 of the low-grade serous carcinoma group,3/16 of the serous borderline tumor group and 2/11 of the non-ovarian benign tumor group(P =0.001).P53 signature,STIC and serous invasive carcinoma occurred only in the fallopian tubal epithelium of patients with high-grade serous ovarian carcinoma,with the positive rates being 29.1%(23/79),15.2%(12/79) and 44.3%(35/79),respectively.Of the 23 cases with p53 signature,17 cases had solitary lesion and 6 cases involved more than two sites.A total of 33 p53 signature positive foci were found,with 22 foci located at fimbria and 11 at ampulla.Bcl-2 expression was demonstrated in 90.9% of those foci(30/33).Of the 12 patients with STIC,7 cases were solitary and 5 cases involved more than two sites.A total of 18 STIC foci were found,with 16 foci located at fimbria and 2 at ampulla.All of them were positive for bcl-2.Conclusions SCOUT is found in fallopian tubal epithelium in patients with serous ovarian epithelial tumors,especially high-grade serious carcinoma.On the other hand,p53 signature,STIC and invasive serous carcinoma of

  17. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... YouTube Videos > NEI YouTube Videos: Amblyopia NEI YouTube Videos YouTube Videos Home Age-Related Macular Degeneration Amblyopia ... of Prematurity Science Spanish Videos Webinars NEI YouTube Videos: Amblyopia NEI on Twitter NEI on YouTube NEI ...

  18. NEI You Tube Videos: Amblyopia

    Science.gov (United States)

    ... NEI YouTube Videos > NEI YouTube Videos: Amblyopia NEI YouTube Videos YouTube Videos Home Age-Related Macular Degeneration ... Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube Videos: Amblyopia NEI on Twitter NEI on YouTube ...

  19. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... NEI YouTube Videos > NEI YouTube Videos: Amblyopia NEI YouTube Videos YouTube Videos Home Age-Related Macular Degeneration ... Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube Videos: Amblyopia NEI on Twitter NEI on YouTube ...

  20. Use of esophageal gastric tube in treatment of upper- and mid-thoracic esophageal cancer%管状胃代食管在胸上中段食管癌治疗中的应用

    Institute of Scientific and Technical Information of China (English)

    曾玉山; 黎萍

    2011-01-01

    目的:探讨管状胃代食管在胸上中段食管癌中的应用价值.方法:回顾性分析2005年1月至2010年12月广东省茂名市中医院收治的60例胸上中段食管癌患者的临床资料,根据术式不同分为管状胃组(30例)和全胃组(30例),观察两组患者手术情况,分别于术前1周、术后1周及术后3周检查患者肺功能.结果:60例患者手术均获得成功,无手术死亡病例.管状胃组与全胃组患者术后并发症发生率分别为26.7%和33.3%,两组比较,差异无统计学意义(P>0.05).术后1周两组患者肺功能比较,差异无统计学意义(P>0.05);与全胃组比较,术后3周管状胃组患者肺功能明显改善(P<0.05).结论:与传统全胃代食管术相比,管状胃代食管术对患者术后肺功能影响相对较小,值得临床推广应用.%Objective; To explore the value of esophageal gastric tube in treatment of upper- and mid-thoracic esophageal cancer. Methods; Between January 2005 and December 2010, the clinical data were retrospectively analyzed in 60 patients with upper- and mid-thoracic esophageal cancer in Maoming Hospital of Traditional Chinese Medicine. The patients were divided into gastric tube and full stomach groups (re =30 each) according to different surgical approaches. Thereafter, the two groups were observed and detected for their lung functions at 1 week before surgery, lw and 3w after surgery, respectively. Results; The surgery was successful in all of 60 patients, and no mortality was found. No difference was found in complication rates between gastric tube (26.7%) and full stomach (33.3%) groups (P>0.05), or in lung function at 1 w after surgery between the two groups (P>0.05). Compared with the full stomach group, the lung function in gastric tube group was significantly improved at 3w after surgery (P < 0. 05). Conclusion: Compared with conventional full stomach esophageal surgery, the esophageal gastric tube surgery is with less adverse effects on

  1. HPV and Cancer

    Science.gov (United States)

    ... Overview Cancer Prevention Overview–for health professionals Research HPV and Cancer On This Page What are human ... hpv/ E-mail: cdcinfo@cdc.gov Human Papillomavirus (HPV) | Did You Know? View this video on YouTube. ...

  2. Gravidez ectópica tubária bilateral: relato de caso A bilateral fallopian tube pregnancy: a case report

    OpenAIRE

    Assis Oberdan Posser; Zélia Berenice Rocha Posser; Cristina Roveré Gehling; Gilberto Ortiz; Bianca Avancini

    1998-01-01

    Gestação ectópica bilateral é a forma mais rara de gestação gemelar, considerando que menos de 250 casos foram relatados na literatura. Nosso caso preenche o critério diagnóstico determinado por Norris9 que requer a demonstração de vilos coriônicos em cada tuba de uterina. Relatamos o caso de uma mulher multípara de 36 anos de idade que desenvolveu um episódio de abdômen agudo hemorrágico. Uma laparotomia realizada com anestesia geral revelou hemoperitônio de 1,8 litros; ambas tubas uterinas ...

  3. MR Features of Primary Fallopian Tube Carcinoma%原发性输卵管癌的磁共振征象分析

    Institute of Scientific and Technical Information of China (English)

    章梦薇; 康林英; 田晓梅; 张鹤; 王士甲; 谷守欣; 张国福

    2014-01-01

    目的:探讨原发性输卵管癌(PFTC)的MRI影像特征.方法:回顾性分析15例经手术及病理证实的原发性输卵管癌的临床资料和MRI表现,总结其MRI影像特征.结果:病灶表现为附件区肿块,单侧14例,双侧1例.9例为囊实性肿块,其中6例肿块呈腊肠形,3例呈不规则形;5例伴不同程度输卵管积水;8例囊性成分于T1WI呈低信号、T2WI呈高信号;1例囊性成分于T1WI、T2WI均呈高信号;实性成分均呈T1WI等或低信号、T2WI不均匀高信号.4例为实性肿块,其中2例呈腊肠形,1例呈卵圆形,1例呈不规则形;呈T1WI低信号、T2WI稍高信号.2例为管状囊性肿块伴管壁乳头状软组织结节,囊液呈T1WI低信号、T2WI高信号,管壁结节呈T1WI稍低信号、T2WI稍高信号.增强后各种实性成分呈明显不均匀强化.伴腹水5例、直肠转移性肿块1例.结论:附件区腊肠形囊实性肿块伴输卵管积水或腊肠形实性肿块是输卵管癌较具特征性的MRI征象.

  4. Lunar Lava Tube Sensing

    Science.gov (United States)

    York, Cheryl Lynn; Walden, Bryce; Billings, Thomas L.; Reeder, P. Douglas

    1992-01-01

    Large (greater than 300 m diameter) lava tube caverns appear to exist on the Moon and could provide substantial safety and cost benefits for lunar bases. Over 40 m of basalt and regolith constitute the lava tube roof and would protect both construction and operations. Constant temperatures of -20 C reduce thermal stress on structures and machines. Base designs need not incorporate heavy shielding, so lightweight materials can be used and construction can be expedited. Identification and characterization of lava tube caverns can be incorporated into current precursor lunar mission plans. Some searches can even be done from Earth. Specific recommendations for lunar lava tube search and exploration are (1) an Earth-based radar interferometer, (2) an Earth-penetrating radar (EPR) orbiter, (3) kinetic penetrators for lunar lava tube confirmation, (4) a 'Moon Bat' hovering rocket vehicle, and (5) the use of other proposed landers and orbiters to help find lunar lava tubes.

  5. Tubing weld cracking test

    International Nuclear Information System (INIS)

    A tubing weld cracking (TWC) test was developed for applications involving advanced austenitic alloys (such as modified 800H and 310HCbN). Compared to the Finger hot cracking test, the TWC test shows an enhanced ability to evaluate the crack sensitivity of tubing materials. The TWC test can evaluate the cracking tendency of base as well as filter materials. Thus, it is a useful tool for tubing suppliers, filler metal producers and fabricators

  6. Categorising YouTube

    OpenAIRE

    Thomas Mosebo Simonsen

    2011-01-01

    This article provides a genre analytical approach to creating a typology of the User Generated Content (UGC) of YouTube. The article investigates the construction of navigation processes on the YouTube website. It suggests a pragmatic genre approach that is expanded through a focus on YouTube’s technological affordances. Through an analysis of the different pragmatic contexts of YouTube, it is argued that a taxonomic understanding of YouTube must be analysed in regards to the vacillation of a...

  7. Steam generator tube performance

    International Nuclear Information System (INIS)

    A survey of steam generator operating experience for 1986 has been carried out for 184 pressurized water and pressurized heavy-water reactors, and 1 water-cooled, graphite-moderated reactor. Tubes were plugged at 75 of the reactors (40.5%). In 1986, 3737 tubes were plugged (0.14% of those in service) and 3148 tubes were repaired by sleeving. A small number of reactors accounted for the bulk of the plugged tubes, a phenomenon consistent with previous years. For 1986, the available tubesheet sludge data for 38 reactors has been compiled into tabular form, and sludge/deposit data will be incorporated into all future surveys

  8. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Your Cancer Prognosis Video View this video on YouTube. Three cancer patients and their doctor, Anthony L. ... One Couple's Creative Response View this video on YouTube. Vanessa, an artist, and her husband Roy discover ...

  9. Steam generator tube failures

    International Nuclear Information System (INIS)

    A review and summary of the available information on steam generator tubing failures and the impact of these failures on plant safety is presented. The following topics are covered: pressurized water reactor (PWR), Canadian deuterium uranium (CANDU) reactor, and Russian water moderated, water cooled energy reactor (VVER) steam generator degradation, PWR steam generator tube ruptures, the thermal-hydraulic response of a PWR plant with a faulted steam generator, the risk significance of steam generator tube rupture accidents, tubing inspection requirements and fitness-for-service criteria in various countries, and defect detection reliability and sizing accuracy. A significant number of steam generator tubes are defective and are removed from service or repaired each year. This wide spread damage has been caused by many diverse degradation mechanisms, some of which are difficult to detect and predict. In addition, spontaneous tube ruptures have occurred at the rate of about one every 2 years over the last 20 years, and incipient tube ruptures (tube failures usually identified with leak detection monitors just before rupture) have been occurring at the rate of about one per year. These ruptures have caused complex plant transients which have not always been easy for the reactor operators to control. Our analysis shows that if more than 15 tubes rupture during a main steam line break, the system response could lead to core melting. Although spontaneous and induced steam generator tube ruptures are small contributors to the total core damage frequency calculated in probabilistic risk assessments, they are risk significant because the radionuclides are likely to bypass the reactor containment building. The frequency of steam generator tube ruptures can be significantly reduced through appropriate and timely inspections and repairs or removal from service

  10. Steam generator tube failures

    Energy Technology Data Exchange (ETDEWEB)

    MacDonald, P.E.; Shah, V.N.; Ward, L.W.; Ellison, P.G.

    1996-04-01

    A review and summary of the available information on steam generator tubing failures and the impact of these failures on plant safety is presented. The following topics are covered: pressurized water reactor (PWR), Canadian deuterium uranium (CANDU) reactor, and Russian water moderated, water cooled energy reactor (VVER) steam generator degradation, PWR steam generator tube ruptures, the thermal-hydraulic response of a PWR plant with a faulted steam generator, the risk significance of steam generator tube rupture accidents, tubing inspection requirements and fitness-for-service criteria in various countries, and defect detection reliability and sizing accuracy. A significant number of steam generator tubes are defective and are removed from service or repaired each year. This wide spread damage has been caused by many diverse degradation mechanisms, some of which are difficult to detect and predict. In addition, spontaneous tube ruptures have occurred at the rate of about one every 2 years over the last 20 years, and incipient tube ruptures (tube failures usually identified with leak detection monitors just before rupture) have been occurring at the rate of about one per year. These ruptures have caused complex plant transients which have not always been easy for the reactor operators to control. Our analysis shows that if more than 15 tubes rupture during a main steam line break, the system response could lead to core melting. Although spontaneous and induced steam generator tube ruptures are small contributors to the total core damage frequency calculated in probabilistic risk assessments, they are risk significant because the radionuclides are likely to bypass the reactor containment building. The frequency of steam generator tube ruptures can be significantly reduced through appropriate and timely inspections and repairs or removal from service.

  11. 留置胃管对胃癌患者围手术期生活质量的影响%Value of nasogastric decompression tube in patients with gastric cancer

    Institute of Scientific and Technical Information of China (English)

    于雪峰; 魏玉哲; 薛英威

    2012-01-01

    目的 探讨胃癌术后留置胃管对术后恢复情况的影响.方法 前瞻性纳入2009年12月至2011年3月间哈尔滨医科大学附属第三医院收治的174例胃癌患者,按随机数字表法分为试验组(88例,术中或术后第1天晨起拔除胃管)和对照组(86例,留置胃管直至排气).比较两组患者术后不适症状、并发症发生情况、恢复时间及住院期间生活质量.结果 与对照组相比,试验组患者术后恶心(14.8%比47.7%,P<0.01)、咽痛(6.8%比38.4%,P<0.01)、饮水后呛咳及异物感(3.4%比20.9%,P<0.01)和咳嗽咳痰不畅(36.4%比55.8%,P<0.05)的发生率明显降低,术后离床时间[(1.46±0.58)d比(1.68±0.61)d,P<0.05]和排气时间[(3.11±0.77)d比(3.75±1.03)d,P<0.05]明显提前.两组术后均未出现吻合口瘘及肠梗阻等严重并发症,吻合口出血发生率的差异亦无统计学意义[3.4% (3/88)比5.8% (5/86),P>0.05].住院期间生活质量表情评分试验组明显优于对照组(平均分3.36比2.78,P<0.01).结论 胃癌术后早期拔除胃管是安全、合理的,可明显提高患者住院期间的生活质量.%Objective To evaluate the effect of nasogastric decompression tube after gastric cancer operation on the postoperative recovery.Methods A toal of 174 patiens with gastric cancer were prospectively enrolled from December 2009 to March 2011 and randomly divided into non-nasogastric tube control group (n=88) and nasogastric tube group (n=86).Postoperative symptoms,complications,recovery time,and quality of life during hospital stay were compared between the two groups.Results The incidences of nausea( 14.8% vs.47.7%,P<0.01),sore throat(6.8% vs.38.4.%,P<0.01),bucking and foreign body sensation (3.4% vs.20.9%,P<0.01),expectorative obstruction (36.4% vs.55.8%,P<0.05) were significantly lower in nasogastric tube group than those in the control group.The intervals to ambulation and flatus were(1.46±0.58) d and

  12. Hologram recording tubes

    Science.gov (United States)

    Rajchman, J. H.

    1973-01-01

    Optical memories allow extremely large numbers of bits to be stored and recalled in a matter of microseconds. Two recording tubes, similar to conventional image-converting tubes, but having a soft-glass surface on which hologram is recorded, do not degrade under repeated hologram read/write cycles.

  13. Welding Tubes In Place

    Science.gov (United States)

    Meredith, R.

    1984-01-01

    Special welding equipment joins metal tubes that carry pressurized cyrogenic fluids. Equipment small enough to be used in confined spaces in which such tubes often mounted. Welded joints lighter in weight and more leak-proof than joints made with mechanical fittings.

  14. Categorising YouTube

    DEFF Research Database (Denmark)

    Simonsen, Thomas Mosebo

    2011-01-01

    This article provides a genre analytical approach to creating a typology of the User Generated Content (UGC) of YouTube. The article investigates the construction of navigation processes on the YouTube website. It suggests a pragmatic genre approach that is expanded through a focus on YouTube’s...... technological affordances. Through an analysis of the different pragmatic contexts of YouTube, it is argued that a taxonomic understanding of YouTube must be analysed in regards to the vacillation of a user-driven bottom-up folksonomy and a hierarchical browsing system that emphasises a culture of competition...... and which favours the already popular content of YouTube. With this taxonomic approach, the UGC videos are registered and analysed in terms of empirically based observations. The article identifies various UGC categories and their principal characteristics. Furthermore, general tendencies of the UGC within...

  15. Cancer

    Science.gov (United States)

    ... Blood tests (which look for chemicals such as tumor markers) Bone marrow biopsy (for lymphoma or leukemia) Chest ... the case with skin cancers , as well as cancers of the lung, breast, and colon. If the tumor has spread ...

  16. Cancer

    Science.gov (United States)

    Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms ... be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors ...

  17. Robotic Tube-Gap Inspector

    Science.gov (United States)

    Gilbert, Jeffrey L.; Gutow, David A.; Maslakowski, John E.

    1993-01-01

    Robotic vision system measures small gaps between nearly parallel tubes. Robot-held video camera examines closely spaced tubes while computer determines gaps between tubes. Video monitor simultaneously displays data on gaps.

  18. [Successful One-lung Ventilation with a Right-sided Double-lumen Tube in a Patient with a Right Upper Tracheal Bronchus, who Underwent Left Pneumonectomy for Left Hilar Lung Cancer].

    Science.gov (United States)

    Kawagoe, Izumi; Kohchiyama, Tsukasa; Hayashida, Masakazu; Satoh, Daizoh; Suzuki, Kenji; Inada, Eiichi

    2016-06-01

    A 60-year-old male patient with left hilar lung cancer was scheduled to undergo left pneumonectomy or left sleeve lower lobectomy. Preoperative computer tomographic and bronchoscopic examinations revealed that the bronchus (B1) to the right apical segment (S1) was a tracheal bronchus (TB) originating from the trachea approximately 10 mm above the carina. Because the left main bronchus was to be dissected, a right-sided double-lumen tube (DLT) was selected to completely protect the right lung from spillage of secretions or cancer cells from the left lung. The right-sided DLT was placed so as to fit its lateral opening of the bronchial lumen to normal upper branches (B2, B3), while sacrificing ventilation of S1 with an abnormal branch (B1). However, one-lung ventilation (OLV) of the right lung could not be achieved, since a gas leakage from the opened tracheal lumen occurred, most probably due to intra-lobar micro-airway communications between S1 and S2/S3. The DLT was withdrawn until the blue bronchial cuff occluded the orifice of the TB (B1). Although the upper half of the blue bronchial cuff appeared above the tracheal carina, OLV through the two bronchial lumen openings could be achieved due to a specific, slanted doughnut shape of the blue bronchial cuff and the location of the abnormal branch (B1) approximate to the carina. Left pneumonectomy using successful OLV was completed safely without hypoxemia or hypercapnea. Our experience indicates that management of OLV for patients with a thoracheal bronchus needs special considerations of the exact location of the TB and intra-lobar micro-airway communications, in addition to types of scheduled surgical procedures. PMID:27483653

  19. Pressure tube type reactor

    International Nuclear Information System (INIS)

    Heretofore, a pressure tube type reactor has a problem in that the evaluation for the reactor core performance is complicate and no sufficient consideration is made for the economical property, to increase the size of a calandria tank and make the cost expensive. Then, in the present invention, the inner diameter of a pressure tube is set to greater than 50% of the lattice gap in a square lattice like arrangement, and the difference between the inner and the outer diameters of the calandria tube is set smaller than 20% of the lattice gap. Further, the inner diameter of the pressure tube is set to greater than 40% and the difference between the inner and the outer diameters of the calandria tube is set smaller than 30% of the lattice gap in a triangle lattice arrangement. Then, heavy water-to-fuel volume ratio can be determined appropriately and the value for the coolant void coefficient is made more negative side, to improve the self controllability inherent to the reactor. In particular, when 72 to 90 fuel rods are arranged per one pressure tube, the power density per one fuel rod is can be increased by about twice. Accordingly, the number of the pressure tubes can be reduced about to one-half, thereby enabling to remarkably decrease the diameter of the reactor core and to reduce the size of the calandria, which is economical. (N.H.)

  20. Kinking of medical tubes.

    Science.gov (United States)

    Ingles, David

    2004-05-01

    The phenomenon of kinking in medical tubing remains a problem for some applications, particularly critical ones such as transporting gasses or fluids. Design features are described to prevent its occurrence.

  1. Power vacuum tubes handbook

    CERN Document Server

    Whitaker, Jerry

    2012-01-01

    Providing examples of applications, Power Vacuum Tubes Handbook, Third Edition examines the underlying technology of each type of power vacuum tube device in common use today. The author presents basic principles, reports on new development efforts, and discusses implementation and maintenance considerations. Supporting mathematical equations and extensive technical illustrations and schematic diagrams help readers understand the material. Translate Principles into Specific Applications This one-stop reference is a hands-on guide for engineering personnel involved in the design, specification,

  2. Aeronautical tubes and pipes

    Science.gov (United States)

    Beauclair, N.

    1984-12-01

    The main and subcomponent French suppliers of aircraft tubes and pipes are discussed, and the state of the industry is analyzed. Quality control is essential for tubes with regard to their i.d. and metallurgical compositions. French regulations do not allow welded seam tubes in hydraulic circuits unless no other form is available, and then rustproofed steel must be installed. The actual low level of orders for any run of tubes dictates that the product is only one of several among the manufacturers' line. Automation, both in NDT and quality control, assures that the tubes meet specifications. A total of 10 French companies participate in the industry, serving both civil and military needs, with some companies specializing only in titanium, steel, or aluminum materials. Concerns wishing to enter the market must upgrade their equipment to meet the higher aeronautical specifications and be prepared to furnish tubes and pipes that serve both functional and structural purposes simultaneously. Additionally, pipe-bending machines must also perform to tight specifications. Pipes can range from 0.2 mm exterior diameter to 40 mm, with wall thicknesses from 0.02 mm to 3 mm. A chart containing a list of manufacturers and their respective specifications and characteristics is presented, and a downtrend in production with reduction of personnel is noted.

  3. Clearing obstructed feeding tubes.

    Science.gov (United States)

    Marcuard, S P; Stegall, K L; Trogdon, S

    1989-01-01

    This is a report of an in vitro study evaluating the ability of six solutions to dissolve clotted enteral feeding, which can cause feeding tube occlusion. The following clotted enteral feeding products were tested: Ensure Plus, Ensure Plus with added protein (Promod 20 g/liter), Osmolite, Enrich, and Pulmocare. Clot dissolution was then tested by adding Adolf's Meat Tenderizer, Viokase, Sprite, Pepsi, Coke, or Mountain Dew. Distilled water served as control. Dissolution score for each mixture was assessed blindly. Best dissolution was observed with Viokase in pH 7.9 solution (p less than 0.01). Similar results were obtained when feeding tube patency was restored in eight in vitro occluded feeding tubes (Dobbhoff, French size 8) by using first Pepsi (two/eight successful) and then Viokase in pH 7.9 (six/six successful). We also report our experience in the first 10 patients with occluded feeding tubes using this Viokase solution injected through a Drum catheter into the feeding tube. In seven patients, this method proved to be successful, and the reasons for failure in three patients include a knotted tube, impacted tablet powder, and a formula clot fo 24 hr duration and 45 cm in length. PMID:2494372

  4. A gas laser tube

    Energy Technology Data Exchange (ETDEWEB)

    Tetsuo, F.; Tokhikhide, N.

    1984-04-19

    A gas laser tube is described in which contamination of the laser gas mixture by the coolant is avoided, resulting in a longer service life of the mirrors. The holder contains two tubes, one inside the other. The laser gas mixture flows through the internal tube. An electrode is fastened to the holder. The coolant is pumped through the slot between the two tubes, for which a hole is cut into the holder. The external tube has a ring which serves to seal the cavity containing the coolant from the atmosphere. The internal tube has two rings, one to seal the laser gas mixture and the other to seal the coolant. A slot is located between these two rings, which leads to the atmosphere (the atmosphere layer). With this configuration, the degradation of the sealing properties of the internal ring caused by interaction with the atmospheric layer is not reflected in the purity of the laser gas mixture. Moreover, pollution of the mirrors caused by the penetration of the coolant into the cavity is eliminated.

  5. [Cancer].

    Science.gov (United States)

    de la Peña-López, Roberto; Remolina-Bonilla, Yuly Andrea

    2016-09-01

    Cancer is a group of diseases which represents a significant public health problem in Mexico and worldwide. In Mexico neoplasms are the second leading cause of death. An increased morbidity and mortality are expected in the next decades. Several preventable risk factors for cancer development have been identified, the most relevant including tobacco use, which accounts for 30% of the cancer cases; and obesity, associated to another 30%. These factors, in turn, are related to sedentarism, alcohol abuse and imbalanced diets. Some agents are well knokn to cause cancer such as ionizing radiation, viruses such as the papilloma virus (HPV) and hepatitis virus (B and C), and more recently environmental pollution exposure and red meat consumption have been pointed out as carcinogens by the International Agency for Research in Cancer (IARC). The scientific evidence currently available is insufficient to consider milk either as a risk factor or protective factor against different types of cancer. PMID:27603890

  6. 留置鼻胃管注食在食管癌同步放化疗中的应用及效果%Application and effect of indwelling nasogastric tube feeding in esophagus cancer concurrent radiochemotherapy

    Institute of Scientific and Technical Information of China (English)

    罗丽群; 冯洁栈

    2015-01-01

    Objective To discuss the effect of indwelling nasogastric tube feeding in esophagus cancer concurrent ra-diochemotherapy. Methods Selected 100 esophagus cancer patients,who were verified by esophagoscope and pathology and had no distant metastasis,admitted from January,2000 to July,2014. Randomly divided them into observation group(n=50) and control group(n=50). Used silica gel nasogastric feeding tube(suggest indwelling in body for less than 45 d),nasogastric tube to feed fluid in stomach on 1 d of observation group′s radiotherapy. Fed control group according to doctor′s diet instruction. Both groups′food type,amount,and frequency were decided according to patients. Observed both groups′nutritive index every 2 weeks during treatment,and the first time acute radioactive esophageal mucosa damage appeared and therapeutic continuity ,and the garde evaluation of acute radiation esophagitis. Results Compared observation group′s nutritive index with control group′s when doing chemoradiotherapy 40 Gy and 60 Gy,differences showing statistical significance(P<0.05). Patients in both groups had dif-ferent degree′s acute radioactive esophagus mucosa damage. All patients in observation group kept radiotherapy ,while 8 patients in control group broke off radiotherapy for 5-9 d when doing 40-45 Gy. Compared the number of patients who broke off radiother-apy because of acute radioactive esophagus mucosa damage in both groups,differences showing statistical significance(P<0.05). Compared the number of level 1,2 radioactive oesophagitis and level 3,4 radioactive oesophagitis,differences showing statistical significance (P<0.01). Conclusion Indwelling nasogastric tube feeding is important in esophagus cancer concurrent ra-diochemotherapy.%目的:探讨留置鼻胃管注食在食管癌同步放化疗中的效果。方法选择2000年1月至2014年7月收治的经食管镜及病理证实且无远处转移的食管癌患者100例,将其随

  7. Dynamic tube/support interaction in heat exchanger tubes

    Energy Technology Data Exchange (ETDEWEB)

    Chen, S.S.

    1991-01-01

    The supports for heat exchanger tubes are usually plates with drilled holes; other types of supports also have been used. To facilitate manufacture and to allow for thermal expansion of the tubes, small clearances are used between tubes and tube supports. The dynamics of tube/support interaction in heat exchangers is fairly complicated. Understanding tube dynamics and its effects is important for heat exchangers. This paper summarizes the current state of the art on this subject and to identify future research needs. Specifically, the following topics are discussed: dynamics of loosely supported tubes, tube/support gap dynamics, tube response in flow, tube damage and wear, design considerations, and future research needs. 55 refs., 1 fig.

  8. Shortening of the 3' untranslated region: an important mechanism leading to overexpression of HMGA2 in serous ovarian cancer

    Institute of Scientific and Technical Information of China (English)

    He Xiangjun; Yang Jing; Zhang Qi; Cui Heng; Zhang Yujun

    2014-01-01

    Background Oncofetal protein high-mobility-group AT-hook protein 2 (HMGA2) is reactivated in serous ovarian cancer (SOC) and its overexpression correlates with poor prognosis.To explore the mechanism,we investigated whether HMGA2 could avoid microRNA regulation due to gene truncation or 3' UTR shortening by alternative polyadenylation.Methods Real-time reverse transcription polymerase chain reaction (RT-PCR) was used to evaluate the abundance of different regions of HMGA2 mRNA in 46 SOC samples.Rapid amplification of cDNA 3' ends (3' RACE) and Southern blotting were used to confirm the shortening of 3' untranslated region (UTR).5' RACE and Southern blotting were used to prove the mRNA decay.Results No significant difference in the ratio of the stable coding region to the fragile region was observed between SOC and control normal fallopian tubes,indicating that the HMGA2 gene is not truncated in SOC.Varying degrees of 3' UTR shortening in SOC samples were observed by comparing the abundance of the proximal region and distal region of the HMGA2 3' UTR.The ratio of the proximal to the distal region of the 3' UTR correlated significantly with expression of the HMGA2 coding region in SOC (r=0.579,P <0.01).Moreover,although the abundance of the HMGA2 coding region varied,all samples,including the very low expressed samples,exhibit relatively high levels of the proximal 3' UTR region,suggesting a dynamic decay of HMGA2 mRNA from the 5' end.The shortening of 3' UTR and the decay from the 5' end were confirmed by 3' RACE,5' RACE and subsequent Southern blotting.Conclusion Heterogeneous 3' UTR lengths render HMGA2 susceptible to different levels of negative regulation by microRNAs,which represents an important mechanism of HMGA2 reactivation in SOC.

  9. Cancer of the Colon and Rectum

    Science.gov (United States)

    ... most common cancer diagnosed in the United States? YouTube embedded video: http://www.youtube-nocookie.com/embed/Vd7Svg131E4?rel=0 YouTube embedded video: http://www.youtube-nocookie.com/embed/ ...

  10. Categorising YouTube

    Directory of Open Access Journals (Sweden)

    Thomas Mosebo Simonsen

    2011-09-01

    Full Text Available This article provides a genre analytical approach to creating a typology of the User Generated Content (UGC of YouTube. The article investigates the construction of navigationprocesses on the YouTube website. It suggests a pragmatic genre approach that is expanded through a focus on YouTube’s technological affordances. Through an analysis of the different pragmatic contexts of YouTube, it is argued that a taxonomic understanding of YouTube must be analysed in regards to the vacillation of a user-driven bottom-up folksonomy and a hierarchical browsing system that emphasises a culture of competition and which favours the already popular content of YouTube. With this taxonomic approach, the UGC videos are registered and analysed in terms of empirically based observations. The article identifies various UGC categories and their principal characteristics. Furthermore, general tendencies of the UGC within the interacting relationship of new and old genres are discussed. It is argued that the utility of a conventional categorical system is primarily of analytical and theoretical interest rather than as a practical instrument.

  11. Effect of tube size on electromagnetic tube bulging

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The commercial finite code ANSYS was employed for the simulation of the electromagnetic tube bulging process. The finite element model and boundary conditions were thoroughly discussed. ANSYS/EMAG was used to model the time varying electromagnetic field in order to obtain the radial and axial magnetic pressure acting on the tube. The magnetic pressure was then used as boundary conditions to model the high velocity deformation of various length tube with ANSYS/LSDYNA. The time space distribution of magnetic pressure on various length tubes was presented. Effect of tube size on the distribution of radial magnetic pressure and axial magnetic pressure and high velocity deformation were discussed. According to the radial magnetic pressure ratio of tube end to tube center and corresponding dimensionless length ratio of tube to coil, the free electromagnetic tube bulging was studied in classification. The calculated results show good agreements with practice.

  12. Kajian Efektifitas Sistem Struktur Tube Dengan Sistem Struktur Tube In Tube Di Bawah Beban Gempa

    OpenAIRE

    Sihotang, Dian Frisca

    2010-01-01

    Berkembangnya teknologi telah melahirkan berbagai sistem struktur bangunan tahan gempa, seperti penggunaan sistem tube.Tube adalah merupakan frame penahan gaya yang menahan gaya gaya lateral dengan struktur kantilever kotak yang memiliki jarak kolom yang berdekatan yang dipasang pada sekeliling gedung, sehingga penampilan wajah depan gedung seperti lubang jendela jendela yang terbuka. Rancangan tube ini kemudian dimodifikasi lagi dengan menambah pengaku pada bagian dalam ( konsep tube in tube...

  13. Downhole pulse tube refrigerators

    Energy Technology Data Exchange (ETDEWEB)

    Swift, G.; Gardner, D. [Los Alamos National Lab., NM (United States). Condensed Matter and Thermal Physics Group

    1997-12-01

    This report summarizes a preliminary design study to explore the plausibility of using pulse tube refrigeration to cool instruments in a hot down-hole environment. The original motivation was to maintain Dave Reagor`s high-temperature superconducting electronics at 75 K, but the study has evolved to include three target design criteria: cooling at 30 C in a 300 C environment, cooling at 75 K in a 50 C environment, cooling at both 75 K and 30 C in a 250 C environment. These specific temperatures were chosen arbitrarily, as representative of what is possible. The primary goals are low cost, reliability, and small package diameter. Pulse-tube refrigeration is a rapidly growing sub-field of cryogenic refrigeration. The pulse tube refrigerator has recently become the simplest, cheapest, most rugged and reliable low-power cryocooler. The authors expect this technology will be applicable downhole because of the ratio of hot to cold temperatures (in absolute units, such as Kelvin) of interest in deep drilling is comparable to the ratios routinely achieved with cryogenic pulse-tube refrigerators.

  14. Prawns in Bamboo Tube

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    Ingredients: 400 grams Jiwei prawns, 25 grams pork shreds, 5 grams sliced garlic. Condiments: 5 grams cooking oil, minced ginger root and scallions, cooking wine, salt, pepper and MSG (optional) Method: 1. Place the Shelled prawns into a bowl and mix with all the condiments. 2. Stuff the prawns into a fresh bamboo tube,

  15. Eustachian tube function in children after insertion of ventilation tubes.

    NARCIS (Netherlands)

    Heerbeek, N. van; Ingels, K.J.A.O.; Snik, A.F.M.; Zielhuis, G.A.

    2001-01-01

    This study was performed to assess the effect of the insertion of ventilation tubes and the subsequent aeration of the middle ear on eustachian tube (ET) function in children. Manometric ET function tests were performed repeatedly for 3 months after the placement of ventilation tubes in 83 children

  16. Restore condition of Incore thimble tubes in guide tubes

    Energy Technology Data Exchange (ETDEWEB)

    Solanas, A.; Izquierdo, J.

    2014-07-01

    Aging of Nuclear Power Plant and succession of outages lead to wear and twist of the thimbles tubes but also to the fooling of Incore guide tubes. These can create friction and a high strength must be used for thimble tubes withdrawal. (Author)

  17. Laser welding of a tube

    International Nuclear Information System (INIS)

    For sleeving PWR steam generator tubes, the welding laser work is made under protection of a primary gas going out by the crossing window of the laser and under a secondary gas flowing axially through the head and the tube

  18. Quarter-wave pulse tube

    Science.gov (United States)

    Swift, G. W.; Gardner, D. L.; Backhaus, S. N.

    2011-10-01

    In high-power pulse-tube refrigerators, the pulse tube itself can be very long without too much dissipation of acoustic power on its walls. The pressure amplitude, the volume-flow-rate amplitude, and the time phase between them evolve significantly along a pulse tube that is about a quarter-wavelength long. Proper choice of length and area makes the oscillations at the ambient end of the long pulse tube optimal for driving a second, smaller pulse-tube refrigerator, thereby utilizing the acoustic power that would typically have been dissipated in the first pulse-tube refrigerator's orifice. Experiments show that little heat is carried from the ambient heat exchanger to the cold heat exchanger in such a long pulse tube, even though the oscillations are turbulent and even when the tube is compactly coiled.

  19. Tubing For Sampling Hydrazine Vapor

    Science.gov (United States)

    Travis, Josh; Taffe, Patricia S.; Rose-Pehrsson, Susan L.; Wyatt, Jeffrey R.

    1993-01-01

    Report evaluates flexible tubing used for transporting such hypergolic vapors as those of hydrazines for quantitative analysis. Describes experiments in which variety of tubing materials, chosen for their known compatibility with hydrazine, flexibility, and resistance to heat.

  20. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... to treatment Seeking Information About Your Prognosis Is a Personal Decision When you have cancer, you and ... how long she has to live. For Doctors, a Patient-Centered Approach View this video on YouTube. ...

  1. Application and Nursing of Nasogastric Tube Enteral Nutrition in Patients With Radical Gastrectomy for Gastric Cancer%鼻饲肠内营养管在胃癌根治术患者治疗中的应用及护理

    Institute of Scientific and Technical Information of China (English)

    高巍

    2015-01-01

    Objective To investigate the clinical effect of nasogastric enteral nutrition and nursing methods of patients treated with radical surgery in the stomach. Methods 320 patients with gastric cancer radical surgery using nasogastric enteral nutrition tube for treatment with clinical data were retrospectively analyzed. Results 320 patients with gastric cancer radical surgery through nasogastric enteral nutrition tube to complete a supplemental nutrition therapy. Through the system of professional care,nasogastric enteral nutrition tube using effect is good,no serious complications occurred. Conclusion The gastric cancer radical surgery patients with nasogastric enteral nutrition tube,can effectively supplement nutrition in patients after operation,reduce the amount of intravenous fluid and promote the recovery of gastrointestinal function in patients,shorten the hospitalization time,reduce the hospitalization costs. The nursing of nasogastric enteral nutrition tube for professional system can ensure the effective use.%目的:探讨鼻饲肠内营养管在胃癌根治术患者治疗中应用的临床效果及护理方法。方法对320例行胃癌根治术应用鼻饲肠内营养管进行治疗患者的临床资料进行回顾性分析。结果320例行胃癌根治术患者都通过鼻饲肠内营养管完成补充营养治疗,通过专业系统的护理,鼻饲肠内营养管使用效果良好,无严重并发症发生。结论胃癌根治术患者应用鼻饲肠内营养管,可以有效地补充患者术后营养,减少静脉补液量,促进患者胃肠道功能恢复,缩短住院时间,降低患者的住院费用。对鼻饲肠内营养管进行专业系统的护理,可以保障其有效使用。

  2. Ultrasonic nondestructive tubing inspection system

    International Nuclear Information System (INIS)

    A system for measuring the extent of tube wall erosion in an inspection region of a heat exchanger tube of a nuclear steam generator, uses an ultrasonic means driven helically inside the eroded tube which may be filled with a fluid (e.g., water) to minimize ultrasonic wave attenuation. A control means cooperates with the ultrasonic means to produce a map of the tube wall thickness in an inspection region

  3. Sleeve puller salvages welded tubes

    Science.gov (United States)

    Weaver, J. F.

    1980-01-01

    Tool removes sleeve remnants without distorting or damaging tubes, unlike pliers and other conventional handtools. Tubes can be reused, saving time, labor, and material in many applications. Sleeve-removal fixture consists of pressure screw, swing arm, locking screws, and base. It removes sleeve remnant from tubing after welded joint has been sawed through.

  4. Enteral Tube Feeding and Pneumonia

    Science.gov (United States)

    Gray, David Sheridan; Kimmel, David

    2006-01-01

    To determine the effects of enteral tube feeding on the incidence of pneumonia, we performed a retrospective review of all clients at our institution who had gastrostomy or jejunostomy tubes placed over a 10-year period. Ninety-three subjects had a history of pneumonia before feeding tube insertion. Eighty had gastrostomy and 13, jejunostomy…

  5. False-positive pH aspirates after nasogastric tube insertion in head and neck tumour.

    Science.gov (United States)

    Sellers, Claudia Kate

    2012-08-27

    Nasogastric (NG) feeding tubes are commonly inserted to supplement enteral nutrition in certain patient groups, including those with head and neck cancers where swallowing may be compromised. An NHS National Patient Safety Alert was released in 2011 detailing ongoing cases of significant morbidity and mortality attached to the incorrect placement of NG feeding tubes in hospital inpatients. Since 2005, there were 21 deaths and 79 cases of harm nationally due to feeding into the lung through misplaced tubes. pH testing remains the first-line method of placement confirmation, with chest x-ray used when no aspirate is gained or where pH testing fails to confirm suitable acidity. We present a case report describing false-positive NG tube placement confirmation tests in a patient with head and neck cancer, who was administered feed into lung parenchyma with significant morbidity. We discuss the case for specific NG tube placement protocols in head and neck cancer patients.

  6. Neural tube defects

    Directory of Open Access Journals (Sweden)

    M.E. Marshall

    1981-09-01

    Full Text Available Neural tube defects refer to any defect in the morphogenesis of the neural tube, the most common types being spina bifida and anencephaly. Spina bifida has been recognised in skeletons found in north-eastern Morocco and estimated to have an age of almost 12 000 years. It was also known to the ancient Greek and Arabian physicians who thought that the bony defect was due to the tumour. The term spina bifida was first used by Professor Nicolai Tulp of Amsterdam in 1652. Many other terms have been used to describe this defect, but spina bifida remains the most useful general term, as it describes the separation of the vertebral elements in the midline.

  7. Fabrication of seamless calandria tubes

    International Nuclear Information System (INIS)

    Full text: Calandria tube is a large diameter, thin walled zircaloy-4 tube and is an important structural component of PHWR type of reactors. These tubes are lifetime components and remain during the full life of the reactor. Calandria tubes are classified as extremely thin walled tubes with a diameter to wall thickness ratio of around 96. Such thin walled tubes are conventionally produced by seam welded route comprising of extrusion of slabs followed by a series of hot and rolling passes, shaping into O-shape and eventual welding. An alternative and superior method of fabricating the calandria tubes, the seamless route, has been developed, which involves hot extrusion of mother blanks followed by three successive cold pilger reductions. Eccentricity correction of the extruded blanks is carried out on a special purpose grinding equipment to bring the wall thickness variation within permissible limits. Predominant wall thickness reductions are given during cold pilgering to ensure high Q-factor values. The texture in the finished tubes could be closely, controlled with an average fr value of 0.65. Pilgering parameters and tube guiding system have been specially designed to facilities rolling of thin walled tubes. Seamless calandria tubes have distinct advantages over welded tubes. In addition to the absence of weld, they are dimensionally more stable, lighter in weight and possess uniform grains with superior grain size. The cycle time from billet to finished product is substantially reduced and the product is amenable to high level of quality assurance. The most significant feature of the seamless route is its material recovery over welded route. Residual stresses measured in the tubes indicate that these are negligible and uniform along the length of the tube. In view of their superior quality, the first charge of seamless calandria tubes will be rolled into the first 500 MWe Pressurised Heavy Water Reactor at Tarapur

  8. Clogging of feeding tubes.

    Science.gov (United States)

    Marcuard, S P; Perkins, A M

    1988-01-01

    This is a report of an in vitro study evaluating clotting ability of some formulas with intact protein and hydrolyzed protein sources in a series of buffers ranging from a pH of 1 thru 10. The following 10 products were tested: Ensure Plus, Ensure, Enrich, Osmolite, Pulmocare, Citrotein, Resource, Vivonex TEN, Vital, and Hepatic Acid II. Protein (10 and 20 g/liter) was added to Citrotein and Ensure Plus. All formulas were tested at full and some at half strength. Clotting occurred only in premixed intact protein formulas (Pulmocare, Ensure Plus, Osmolite, Enrich, Ensure) and in Resource. No clotting was observed for Citrotein (intact protein formula in powder form), Vital, Vivonex TEN, and Hepatic Aid II. Adding protein did not cause or increase clotting. In summary, clotting of some liquid formula diet appears to be an important factor causing possible gastric feeding tube occlusion. The following measures may help in preventing this problem: flushing before and after aspirating for gastric residuals to eliminate acid precipitation of formula in the feeding tube, advance the nasogastric feeding tube into the duodenum if possible, and avoid mixing these products with liquid medications having a pH value of 5.0 or less. PMID:3138452

  9. Traveling-Wave Tubes

    Science.gov (United States)

    Kory, Carol L.

    1998-01-01

    The traveling-wave tube (TWT) is a vacuum device invented in the early 1940's used for amplification at microwave frequencies. Amplification is attained by surrendering kinetic energy from an electron beam to a radio frequency (RF) electromagnetic wave. The demand for vacuum devices has been decreased largely by the advent of solid-state devices. However, although solid state devices have replaced vacuum devices in many areas, there are still many applications such as radar, electronic countermeasures and satellite communications, that require operating characteristics such as high power (Watts to Megawatts), high frequency (below 1 GHz to over 100 GHz) and large bandwidth that only vacuum devices can provide. Vacuum devices are also deemed irreplaceable in the music industry where musicians treasure their tube-based amplifiers claiming that the solid-state and digital counterparts could never provide the same "warmth" (3). The term traveling-wave tube includes both fast-wave and slow-wave devices. This article will concentrate on slow-wave devices as the vast majority of TWTs in operation fall into this category.

  10. CRL X-RAY TUBE

    OpenAIRE

    Kolchevsky, N. N.; Petrov, P. V.

    2015-01-01

    A novel types of X-ray tubes with refractive lenses are proposed. CRL-R X-ray tube consists of Compound Refractive Lens- CRL and Reflection X-ray tube. CRL acts as X-ray window. CRL-T X-ray consists of CRL and Transmission X-ray tube. CRL acts as target for electron beam. CRL refractive lens acts as filter, collimator, waveguide and focusing lens. Properties and construction of the CRL X-ray tube are discussed.

  11. Reliability of steam generator tubing

    Energy Technology Data Exchange (ETDEWEB)

    Kadokami, E. [Mitsubishi Heavy Industries Ltd., Hyogo-ku (Japan)

    1997-02-01

    The author presents results on studies made of the reliability of steam generator (SG) tubing. The basis for this work is that in Japan the issue of defects in SG tubing is addressed by the approach that any detected defect should be repaired, either by plugging the tube or sleeving it. However, this leaves open the issue that there is a detection limit in practice, and what is the effect of nondetectable cracks on the performance of tubing. These studies were commissioned to look at the safety issues involved in degraded SG tubing. The program has looked at a number of different issues. First was an assessment of the penetration and opening behavior of tube flaws due to internal pressure in the tubing. They have studied: penetration behavior of the tube flaws; primary water leakage from through-wall flaws; opening behavior of through-wall flaws. In addition they have looked at the question of the reliability of tubing with flaws during normal plant operation. Also there have been studies done on the consequences of tube rupture accidents on the integrity of neighboring tubes.

  12. Microdischarges in DC accelerator tubes

    International Nuclear Information System (INIS)

    Voltage tests on the Daresbury ceramic/titanium accelerator tube have shown that microdischarges play an important role in the conditioning process. It has been found that the voltage onset for microdischarges in a tube is dependent on the surface contamination of the electrodes and the tube geometry (in particular the tube length). This geometrical effect can be related to the trajectories of secondary ions emitted from the electrode surfaces. Sensitive diagnostic techniques have been developed to study the mass and energy distribution of ions emitted along the axis of the tube during these predischarges. The energy distribution of protons (and H- ions) can be related to the origins of the discharges in the tube. Detailed results are presented for a particular tube geometry. (author)

  13. Ultrasonic inspection of tube to tube plate welds

    International Nuclear Information System (INIS)

    To monitor the deterioration of a weld between a tube and tube plate which has been repaired by a repair sleeve inside the tube and brazed at one end to the tube, ultrasound from a crystal at the end of a rod is launched, in the form of Lamb-type waves, into the tube through the braze and allowed to travel along the tube to the weld and be reflected back along the tube. The technique may also be used for the type of heat exchanger in which, during construction, the tubes are welded to the tube plate via external sleeves in which case the ultrasound is used in a similar manner to inspect the sleeve/tube plate weld. an electromagnetic transducer may be used to generate the ultrasound. The ultrasonic head comprising the crystal and an acoustic baffle is mounted on a Perspex (RTM) rod which may be rotated by a stepping motor. Echo signals from the region of deterioration may be isolated by use of a time gate in the receiver. The device primarily detects circumferentially orientated cracks, and may be used in heat exchangers in nuclear power plants. (author)

  14. CANCER

    Directory of Open Access Journals (Sweden)

    N. Kavoussi

    1973-09-01

    Full Text Available There are many carcinogenetic elements in industry and it is for this reason that study and research concerning the effect of these materials is carried out on a national and international level. The establishment and growth of cancer are affected by different factors in two main areas:-1 The nature of the human or animal including sex, age, point and method of entry, fat metabolism, place of agglomeration of carcinogenetic material, amount of material absorbed by the body and the immunity of the body.2 The different nature of the carcinogenetic material e.g. physical, chemical quality, degree of solvency in fat and purity of impurity of the element. As the development of cancer is dependent upon so many factors, it is extremely difficult to determine whether a causative element is principle or contributory. Some materials are not carcinogenetic when they are pure but become so when they combine with other elements. All of this creates an industrial health problem in that it is almost impossible to plan an adequate prevention and safety program. The body through its system of immunity protects itself against small amounts of carcinogens but when this amount increases and reaches a certain level the body is not longer able to defend itself. ILO advises an effective protection campaign against cancer based on the Well –equipped laboratories, Well-educated personnel, the establishment of industrial hygiene within factories, the regular control of safety systems, and the implementation of industrial health principles and research programs.

  15. Chromatin H3K27me3/H3K4me3 histone marks define gene sets in high-grade serous ovarian cancer that distinguish malignant, tumour-sustaining and chemo-resistant ovarian tumour cells.

    Science.gov (United States)

    Chapman-Rothe, N; Curry, E; Zeller, C; Liber, D; Stronach, E; Gabra, H; Ghaem-Maghami, S; Brown, R

    2013-09-19

    In embryonic stem (ES) cells, bivalent chromatin domains containing H3K4me3 and H3K27me3 marks silence developmental genes, while keeping them poised for activation following differentiation. We have identified gene sets associated with H3K27me3 and H3K4me3 marks at transcription start sites in a high-grade ovarian serous tumour and examined their association with epigenetic silencing and malignant progression. This revealed novel silenced bivalent marked genes, not described previously for ES cells, which are significantly enriched for the PI3K (P<10(-7)) and TGF-β signalling pathways (P<10(-5)). We matched histone marked gene sets to gene expression sets of eight normal fallopian tubes and 499 high-grade serous malignant ovarian samples. This revealed a significant decrease in gene expression for the H3K27me3 and bivalent gene sets in malignant tissue. We then correlated H3K27me3 and bivalent gene sets to gene expression data of ovarian tumour 'stem cell-like' sustaining cells versus non-sustaining cells. This showed a significantly lower expression for the H3K27me3 and bivalent gene sets in the tumour-sustaining cells. Similarly, comparison of matched chemo-sensitive and chemo-resistant ovarian cell lines showed a significantly lower expression of H3K27me3/bivalent marked genes in the chemo-resistant compared with the chemo-sensitive cell line. Our analysis supports the hypothesis that bivalent marks are associated with epigenetic silencing in ovarian cancer. However it also suggests that additional tumour specific bivalent marks, to those known in ES cells, are present in tumours and may potentially influence the subsequent development of drug resistance and tumour progression. PMID:23128397

  16. Sealed ion accelerator tubes (survey)

    International Nuclear Information System (INIS)

    The first publications on developing commercial models of small-scale sealed accelerator tubes in which neutrons are generated appeared in the foreign press in 1954 to 1957; they were very brief and were advertising-oriented. The tubes were designed for neutron logging of oil wells instead of ampule neutron sources (Po + Be, Ra + Be). Later, instruments of this type began to be called neutron tubes from the resulting neutron radiation that they gave off. In Soviet Union a neutron tube was developed in 1958 in connection with the development of the pulsed neutron-neutron method of studying the geological profile of oil wells. At that time the tube developed was intended, in the view of its inventors, to replace standard isotope sources with constant neutron yield. A fairly detailed survey of neutron tubes was made in the studies. 8 refs., 8 figs

  17. Steam generator tube integrity program

    Energy Technology Data Exchange (ETDEWEB)

    Dierks, D.R.; Shack, W.J. [Argonne National Laboratory, IL (United States); Muscara, J.

    1996-03-01

    A new research program on steam generator tubing degradation is being sponsored by the U.S. Nuclear Regulatory Commission (NRC) at Argonne National Laboratory. This program is intended to support a performance-based steam generator tube integrity rule. Critical areas addressed by the program include evaluation of the processes used for the in-service inspection of steam generator tubes and recommendations for improving the reliability and accuracy of inspections; validation and improvement of correlations for evaluating integrity and leakage of degraded steam generator tubes, and validation and improvement of correlations and models for predicting degradation in steam generator tubes as aging occurs. The studies will focus on mill-annealed Alloy 600 tubing, however, tests will also be performed on replacement materials such as thermally-treated Alloy 600 or 690. An overview of the technical work planned for the program is given.

  18. The Application of Used Extracorporeal Blood Circuit Tube Governor in Nasal Feeding Nursing of Postoperative Patients with Laryngeal Cancer%体外循环血路管调速器在喉癌术后患者鼻饲饮食护理中的应用

    Institute of Scientific and Technical Information of China (English)

    郝小丹; 徐光

    2016-01-01

    Objective To discuss the application of used extracorporeal blood circuit tube governor in the nasal feeding nursing of postoperative patients with laryngeal caner. Methods 65 cases were randomly divided into 2 groups:group A (n=30) and group B (n=35);ordinary nasogastric tube was applied to cases in group A while nasogastric tube with extracorporeal blood circuit tube governor was applied to cases in group B;the time for nasal feeding nursing of the cases in the 2 groups was recorded as well as the occurrence of gastric tube damage. Results The average time of nasal feeding nursing once in group A was 8.6 minutes while that was 6.2 minutes in group B;gastric tube damage occurred in 4 cases in group A (13.3%) while no gastric tube damage occurred in group B. Conclusions It can reduce the gastric tube damage, prevent gastric distention and shorten the time of nursing to apply used extracorporeal blood circuit tube governor in the nasal feeding nursing of postoperative patients with laryngeal cancer, and it is worthy of wider application in clinic.%目的:探讨体外循环血路管调速器在喉癌术后患者鼻饲饮食护理中的应用效果。方法选择65例喉癌术后留置胃管的患者随机分为A组30例,B组35例,A组使用普通胃管进行鼻饲饮食,B组使用安装了体外循环血路管调速器的胃管进行鼻饲饮食。统计两组患者鼻饲饮食的护理时间、胃管破损发生率。结果 A组平均每次鼻饲饮食护理时间为8.6分钟,B组为6.2分钟。A组患者鼻饲过程中胃管破损而重新置入胃管4例(13.3%),B组未发生胃管破损。结论在喉癌术后患者的鼻饲饮食中使用安装了体外循环血路管调速器的胃管,可以减少胃管破损,避免胃胀气,缩短护理时间,值得临床推广。

  19. Alternate tube plugging criteria for steam generator tubes

    Energy Technology Data Exchange (ETDEWEB)

    Cueto-Felgueroso, C.; Aparicio, C.B. [Tecnatom, S.A., Madrid (Spain)

    1997-02-01

    The tubing of the Steam Generators constitutes more than half of the reactor coolant pressure boundary. Specific requirements governing the maintenance of steam generator tubes integrity are set in Plant Technical Specifications and in Section XI of the ASME Boiler and Pressure Vessel Code. The operating experience of Steam Generator tubes of PWR plants has shown the existence of some types of degradatory processes. Every one of these has an specific cause and affects one or more zones of the tubes. In the case of Spanish Power Plants, and depending on the particular Plant considered, they should be mentioned the Primary Water Stress Corrosion Cracking (PWSCC) at the roll transition zone (RTZ), the Outside Diameter Stress Corrosion Cracking (ODSCC) at the Tube Support Plate (TSP) intersections and the fretting with the Anti-Vibration Bars (AVBs) or with the Support Plates in the preheater zone. The In-Service Inspections by Eddy Currents constitutes the standard method for assuring the SG tubes integrity and they permit the monitoring of the defects during the service life of the plant. When the degradation reaches a determined limit, called the plugging limit, the SG tube must be either repaired or retired from service by plugging. Customarily, the plugging limit is related to the depth of the defect. Such depth is typically 40% of the wall thickness of the tube and is applicable to any type of defect in the tube. In its origin, that limit was established for tubes thinned by wastage, which was the predominant degradation in the seventies. The application of this criterion for axial crack-like defects, as, for instance, those due to PWSCC in the roll transition zone, has lead to an excessive and unnecessary number of tubes being plugged. This has lead to the development of defect specific plugging criteria. Examples of the application of such criteria are discussed in the article.

  20. YouTube and 'psychiatry'.

    Science.gov (United States)

    Gordon, Robert; Miller, John; Collins, Noel

    2015-12-01

    YouTube is a video-sharing website that is increasingly used to share and disseminate health-related information, particularly among younger people. There are reports that social media sites, such as YouTube, are being used to communicate an anti-psychiatry message but this has never been confirmed in any published analysis of YouTube clip content. This descriptive study revealed that the representation of 'psychiatry' during summer 2012 was predominantly negative. A subsequent smaller re-analysis suggests that the negative portrayal of 'psychiatry' on YouTube is a stable phenomenon. The significance of this and how it could be addressed are discussed.

  1. YouTube and 'psychiatry'.

    Science.gov (United States)

    Gordon, Robert; Miller, John; Collins, Noel

    2015-12-01

    YouTube is a video-sharing website that is increasingly used to share and disseminate health-related information, particularly among younger people. There are reports that social media sites, such as YouTube, are being used to communicate an anti-psychiatry message but this has never been confirmed in any published analysis of YouTube clip content. This descriptive study revealed that the representation of 'psychiatry' during summer 2012 was predominantly negative. A subsequent smaller re-analysis suggests that the negative portrayal of 'psychiatry' on YouTube is a stable phenomenon. The significance of this and how it could be addressed are discussed. PMID:26755987

  2. Learning from YouTube [Video Book

    Science.gov (United States)

    Juhasz, Alexandra

    2011-01-01

    YouTube is a mess. YouTube is for amateurs. YouTube dissolves the real. YouTube is host to inconceivable combos. YouTube is best for corporate-made community. YouTube is badly baked. These are a few of the things Media Studies professor Alexandra Juhasz (and her class) learned about YouTube when she set out to investigate what actually happens…

  3. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Questions to Ask about Your Diagnosis Research Understanding Cancer Prognosis Oncologist Anthony L. Back, M.D., a ... for provider care teams (PDF-210KB). Understanding Your Cancer Prognosis Video View this video on YouTube. Three ...

  4. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Your Diagnosis Research Understanding Cancer Prognosis Oncologist Anthony L. Back, M.D., a national expert on doctor- ... YouTube. Three cancer patients and their doctor, Anthony L. Back, M.D. -- an oncologist who is also ...

  5. Infrared imaging of LED lighting tubes and fluorescent tubes

    Science.gov (United States)

    Siikanen, Sami; Kivi, Sini; Kauppinen, Timo; Juuti, Mikko

    2011-05-01

    The low energy efficiency of conventional light sources is mainly caused by generation of waste heat. We used infrared (IR) imaging in order to monitor the heating of both LED tube luminaires and ordinary T8 fluorescent tubes. The IR images showed clearly how the surface temperatures of the fluorescent tube ends quickly rose up to about +50...+70°C, whereas the highest surface temperatures seen on the LED tubes were only about +30...+40°C. The IR images demonstrated how the heat produced by the individual LED chips can be efficiently guided to the supporting structure in order to keep the LED emitters cool and hence maintain efficient operation. The consumed electrical power and produced illuminance were also recorded during 24 hour measurements. In order to assess the total luminous efficacy of the luminaires, separate luminous flux measurements were made in a large integrating sphere. The currently available LED tubes showed efficacies of up to 88 lm/W, whereas a standard "cool white" T8 fluorescent tube produced ca. 75 lm/W. Both lamp types gave ca. 110 - 130 lx right below the ceiling-mounted luminaire, but the LED tubes consume only 40 - 55% of the electric power compared to fluorescent tubes.

  6. Forming tool improves quality of tubing flares

    Science.gov (United States)

    1966-01-01

    Punch and die set improves the quality of tubing flares for use with standard flared-tube fittings in high-pressure systems. It forges a dimensionally accurate flare in the tubing and forces more tubing material into the high-stress areas to improve the strength and tightness of the tubing connection.

  7. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Vision Research & Ophthalmology (DIVRO) Student Training Programs NEI Home About NEI Health Information News and Events Grants ... Research at NEI Education Programs Training and Jobs Home > NEI YouTube Videos > NEI YouTube Videos: Amblyopia NEI ...

  8. Flaming on YouTube

    NARCIS (Netherlands)

    Moor, Peter J.; Heuvelman, Ard; Verleur, Ria

    2010-01-01

    In this explorative study, flaming on YouTube was studied using surveys of YouTube users. Flaming is defined as displaying hostility by insulting, swearing or using otherwise offensive language. Three general conclusions were drawn. First, although many users said that they themselves do not flame,

  9. HF electronic tubes. Technologies, grid tubes and klystrons

    International Nuclear Information System (INIS)

    This article gives an overview of the basic technologies of electronic tubes: cathodes, electronic optics, vacuum and high voltage. Then the grid tubes, klystrons and inductive output tubes (IOT) are introduced. Content: 1 - context and classification; 2 - electronic tube technologies: cathodes, electronic optics, magnetic confinement (linear tubes), periodic permanent magnet (PPM) focussing, collectors, depressed collectors; 3 - vacuum technologies: vacuum quality, surface effects and interaction with electrostatic and RF fields, secondary emission, multipactor effect, thermo-electronic emission; 4 - grid tubes: operation of a triode, tetrodes, dynamic operation and classes of use, 'common grid' and 'common cathode' operation, ranges of utilisation and limitations, operation of a tetrode on unadjusted load, lifetime of a tetrode, uses of grid tubes; 5 - klystrons: operation, impact of space charge, multi-cavity klystrons, interaction efficiency, extended interaction klystrons, relation between interaction efficiency, perveance and efficiency, ranges of utilization and power limitations, multi-beam klystrons and sheet beam klystrons, operation on unadjusted load, klystron band pass and lifetime, uses; 6 - IOT: principle of operation, ranges of utilisation and limitations, interaction efficiency and depressed collector IOT, IOT lifetime and uses. (J.S.)

  10. Loss of SerpinA5 protein expression is associated with advanced-stage serous ovarian tumors

    NARCIS (Netherlands)

    Bijsmans, Ingrid T. G. W.; Smits, Kim M.; de Graeff, Pauline; Wisman, G. Bea A.; van der Zee, Ate G. J.; Slangen, Brigitte F.; de Bruine, Adriaan P.; van Engeland, Manon; Sieben, Nathalie L.; Van de Vijver, Koen K.

    2011-01-01

    Epithelial ovarian cancer, the most lethal neoplasm of the female genital tract, is usually diagnosed at an advanced stage as obvious symptoms are absent at early stages. This disease is believed to originate from malignant transformation of the ovarian surface epithelium or fallopian tube. Histolog

  11. Conditioning and breakdown phenomena in accelerator tubes

    International Nuclear Information System (INIS)

    Important breakdown mechanisms in accelerator tubes are reviewed, and discharge phenomena in NEC tubes are deduced from the surface appearance of the electrodes and insulators of a used tube. Microphotos of these surfaces are shown

  12. Vidicon storage tube electrical input/output

    Science.gov (United States)

    Lipoma, P.

    1972-01-01

    Electrical data storage tube is assembled from standard vidicon tube using conventional amplification and control circuits. Vidicon storage tube is simple, inexpensive and has an erase and preparation time of less than 5 microseconds.

  13. Electronic components, tubes and transistors

    CERN Document Server

    Dummer, G W A

    1965-01-01

    Electronic Components, Tubes and Transistors aims to bridge the gap between the basic measurement theory of resistance, capacitance, and inductance and the practical application of electronic components in equipments. The more practical or usage aspect of electron tubes and semiconductors is given emphasis over theory. The essential characteristics of each main type of component, tube, and transistor are summarized. This book is comprised of six chapters and begins with a discussion on the essential characteristics in terms of the parameters usually required in choosing a resistor, including s

  14. PEG tubes: dealing with complications.

    Science.gov (United States)

    Malhi, Hardip; Thompson, Rosie

    A percutaneous endoscopic gastronomy tube can be used to deliver nutrition, hydration and medicines directly into the patient's stomach. Patients will require a tube if they are unable to swallow safely, putting them at risk of aspiration of food, drink and medicines into their lungs. It is vital that nurses are aware of the complications that may arise when caring for a patient with a PEG tube. It is equally important that nurses know how to deal with these complications or from where tc seek advice. This article provides a quick troubleshooting guide to help nurses deal with complications that can arise with PEG feeding.

  15. PEG tubes: dealing with complications.

    Science.gov (United States)

    Malhi, Hardip; Thompson, Rosie

    A percutaneous endoscopic gastronomy tube can be used to deliver nutrition, hydration and medicines directly into the patient's stomach. Patients will require a tube if they are unable to swallow safely, putting them at risk of aspiration of food, drink and medicines into their lungs. It is vital that nurses are aware of the complications that may arise when caring for a patient with a PEG tube. It is equally important that nurses know how to deal with these complications or from where tc seek advice. This article provides a quick troubleshooting guide to help nurses deal with complications that can arise with PEG feeding. PMID:26016095

  16. Cancer Basics

    Science.gov (United States)

    ... Cancer? Breast Cancer Colon/Rectum Cancer Lung Cancer Prostate Cancer Skin Cancer Show All Cancer Types News and Features Cancer Glossary ACS Bookstore Cancer Information Cancer Basics Cancer Prevention & Detection Signs & Symptoms of Cancer Treatments & Side Effects ...

  17. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Funding Division of Extramural Activities Division of Extramural Science Programs Funding Opportunity Announcements Funding Mechanisms Supported by ... Amaurosis Low Vision Refractive Errors Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube Videos: Amblyopia NEI ...

  18. Lunar Core Drive Tubes Summary

    Data.gov (United States)

    National Aeronautics and Space Administration — Contains a brief summary and high resolution imagery from various lunar rock and core drive tubes collected from the Apollo and Luna missions to the moon.

  19. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Eye Disease Dilated Eye Exam Dry Eye For Kids Glaucoma Healthy Vision Tips Leber Congenital Amaurosis Low Vision Refractive Errors Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube Videos: Amblyopia NEI ...

  20. drift tube for linear accelerator

    CERN Multimedia

    A drift tube from the Linac 1. This was the first tank of the linear accelerator Linac1, the injection system for the Proton Synchrotron, It ran for 34 years (1958 - 1992). Protons entered at the far end and were accelerated between the copper drift tubes by an oscillating electromagnetic field. The field flipped 200 million times a second (200 MHz) so the protons spent 5 nanoseconds crossing a drift tube and a gap. Moving down the tank, the tubes and gaps had to get longer as the protons gained speed. The tank accelerated protons from 500 KeV to 10 MeV. Linac1 was also used to accelerate deutrons and alpha particles for the Intersecting Storage Rings and oxygen and sulpher ions for the Super Proton Synchrotron heavy ion programme.

  1. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Funding Division of Extramural Affairs Division of Extramural Science Programs Funding Opportunity Announcements Funding Mechanisms Supported by ... Amaurosis Low Vision Refractive Errors Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube Videos: Amblyopia NEI ...

  2. Design and Fabrication of Carbon Nano tube for Medical Application

    International Nuclear Information System (INIS)

    Carbon nano tubes or known as CNTs are allotropes of carbon with a cylindrical nano structure. They exhibit extraordinary strength and unique electrical properties, and are efficient thermal conductors [1]. Due to its ordinary properties this research will based on BIOSENSOR device. Normally these CNTs biosensor are based on an enzyme catalyzed reaction that will produce either electrons or protons. In particular, it is useful in genetic profiling of human diseases, which includes in identifying genes that are expressed in certain diseases such as cancer [2]. This research will based on design and fabricate sensor or device using carbon nano tube and integrate carbon nano tube (CNTs) onto wafer using combination of dichlorophosphate and nano manipulation. Carbon nano tubes device mask are design using AUTOCAD software; there is four mask involved, first mask is Gate Formation,second mask is insulation layer third mask is source and drain and final mask forth mask is used as test channel. For fabrication and optimization of biosensor using carbon nano tube CNT that will be involve both microfabrication and nano fabrication. This process will involve conventional photolithography process, electron beam evaporator, thermal oxidation and wet etching process. To inspect and characterize carbon nano tube electrical properties it will involve tools such as SEM, AFM, Dielectric Analyzer, IV-CV and Semiconductor Parametric Analyzer system. This inspection is very important to produce a perfect profile to produce a good biosensor based on carbon nano tube structure. Preparation of various samples for testing functionality of the device this various samples and conditions will be done to ensure the detection is precise. Conductivity and capacitance effect will be tested electrically to detect the hybridization of the sample. (author)

  3. The YouTube reader

    OpenAIRE

    2009-01-01

    YouTube has come to epitomize the possibilities of digital culture. With more than seventy million unique users a month and approximately eighty million videos online, this brand-name video distribution platform holds the richest repository of popular culture on the Internet. As the fastest growing site in the history of the Web, YouTube promises endless new opportunities for amateur video, political campaigning, entertainment formats, and viral marketing—a clip culture that has seemed to out...

  4. Eddy current tube testing unit

    International Nuclear Information System (INIS)

    The unit described can check a wide variety of tubes in quick succession and its modular design gives it a high degree of versability. Suitably defined working conditions and specific fittings enable most of the faults encountered in the manufacture of a tube to be detected. By appropriate means of selection based on signal amplitude, phase and frequency analyses it is possible to adapt selection criteria to the seriousness of the different categories of defect

  5. Test-tube Baby Option

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    As China’s first test tube baby celebrates her 20th birthday,the country is moving to improve IVF procedures I feel just like a normal person,despite being a little bit hi-tech,"said China’s first test-tube baby Zheng Mengzhu at her birthday party in Beijing. Zheng,born on March 10,1988 in the No.3 Hospital affiliated to the Peking University of Medical Sciences,made a trip

  6. Impending Carotid Blowout Stabilization Using an LT-D Tube

    Directory of Open Access Journals (Sweden)

    G. Desuter

    2014-01-01

    Full Text Available Adequate stabilization of a patient presenting with a carotid blowout is one of the most challenging issues an on-call ENT surgeon can be confronted with. Reducing the bleeding and securing the airway are essential before more definitive management. We present the case of a 72-year-old patient with head and neck cancer who arrived at the emergency room with a carotid blowout and who was successfully stabilized using a King LT-D ventilation tube.

  7. A laser tube position regulator

    Energy Technology Data Exchange (ETDEWEB)

    Sinyitiro, A.; Norio, K.

    1984-03-26

    An improved design is patented for a mechanism and method of regulating, with a high degree of accuracy, the position of a laser tube in a gas laser inside the optical resonator formed by external mirrors. The laser tube is held in two holders. Each holder contains an L shaped bracket which supports a semitransparent plate. The plate is positioned so that its center is over the center of the end of the tube which is in the form of a Brewster window. A narrow parallel beam is directed along the tube axis from an external auxiliary laser. The beam passes through the semitransparent mirror of the optical resonator in the adjusted laser, through the first Brewster window, the tube itself, and the second Brewster window and is reflected back in the reverse direction from a fully reflecting mirror in the optical resonator. This provides partial reflection of the beam from the external Brewster mirror surface. The tube position in the holders is regulated continuously so that the luminous spots from the beams reflected off the Brewster windows fall on the semitransparent plates in the center of the latter which is designated as the point of intersection.

  8. Avaliação da reconstrução do trato alimentar com tubo gástrico ou colônico na esofagectomia por câncer de esôfago Evaluation of the reconstruction techniques of the alimentary tract with gastric or colonic tube in esophagectomy for esophageal cancer

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Pinto

    2008-12-01

    Full Text Available OBJETIVO: Relatar a experiência com as principais técnicas de reconstrução do trato alimentar após esofagectomia por câncer de esôfago. METODOS: Foram analisados retrospectivamente 68 pacientes submetidos à esofagectomia entre fevereiro de 1997 e novembro de 2005. Todos os pacientes incluídos no estudo foram submetidos à esofagectomia com reconstrução com tubo gástrico ou colônico e anastomose cervical. RESULTADOS: A idade média foi de 55,4 anos (25-74 anos, 50 pacientes eram do sexo masculino e 18 pacientes do sexo feminino, 27 pacientes apresentavam o tumor localizado no esôfago médio e 41 pacientes no esôfago distal, sendo carcinoma epidermóide em 35 pacientes e adenocarcinoma em 33 pacientes. A ressecção foi por via transtorácica em 35 indivíduos e por via transhiatal em 33. A reconstrução com tubo gástrico se deu em 58 pacientes e com tubo colônico em 10 pacientes. A morbidade total da série foi de 52,9%. A mortalidade operatória foi de 5,8%. A sobrevida média foi de 35 meses. CONCLUSÃO: A esofagectomia com reconstrução com tubo gástrico e anastomose cervical é factível tecnicamente, sendo um procedimento realizado de rotina nos pacientes portadores de câncer de esôfago com indicação cirúrgica. Utilizamos, e recomendamos, a reconstrução com tubo colônico principalmente nos pacientes com cirurgia prévia no estômago ou quando da necessidade de ressecção ampliada deste, impossibilitando a confecção da reconstrução do trânsito alimentar com a gastroplastia.BACKGROUND: To describe the main reconstruction techniques of the alimentary tract after esophagectomy due to esophagus cancer in patients enrolled. METHODS: We analyzed retrospectively 68 patients submitted to the esophagectomy between february of 1997 and november of 2005. All of the patients included in the study were submitted to the reconstruction with gastric tube and colon segment and cervical anastomosis. RESULTS: The mean age was

  9. Osmotic regulation of seamless tube growth.

    Science.gov (United States)

    Schottenfeld-Roames, Jodi; Ghabrial, Amin S

    2013-02-01

    Most organs are composed of tubes of differing cellular architectures, including intracellular 'seamless' tubes. Two studies examining the morphogenesis of the seamless tubes formed by the excretory canal cell in Caenorhabditis elegans reveal a previously unappreciated role for osmoregulation of tubulogenesis: hyperosmotic shock recruits canalicular vesicles to the lumenal membrane to promote seamless tube growth. PMID:23377027

  10. Osmotic regulation of seamless tube growth

    OpenAIRE

    Schottenfeld-Roames, Jodi; Ghabrial, Amin S.

    2013-01-01

    Most organs are composed of tubes of differing cellular architectures, including intracellular, “seamless” tubes. Two studies examining the morphogenesis of the C. elegans excretory canal cell seamless tubes reveal a previously unappreciated role for osmoregulation of tubulogenesis: hyperosmotic shock recruits canalicular vesicles to the lumenal membrane to promote seamless tube growth.

  11. Pump element for a tube pump

    DEFF Research Database (Denmark)

    2011-01-01

    relative to the rod element so as to allow for a fluid flow in the tube through the first valve member, along the rod element, and through the second valve member. The tube comprises an at least partly flexible tube portion between the valve members such that a repeated deformation of the flexible tube...... pump as mentioned above, thereby acting to generate a fluid flow through the tube upon repeated deformation of the tube between the two valve members. The pump element may comprise a connecting part for coupling to another tube and may comprise a sealing part establishing a fluid tight connection...

  12. Current practices for ultrasonic and radiographic examination of tubes, tube plates and tube-plate welds of tube bundles in heat exchangers. Chapter 3

    International Nuclear Information System (INIS)

    The chapter describes the ultrasonic and radiographic inspection procedures that are applied to heat exchanger tube bundles. The inspection process starts with the ultrasonic examination of the tubes and tube plates during manufacture, followed by radiography of the tube-to-tube-plate welds during fabrication of the tube bundle. Ultrasonic methods are explained for welds which are amenable to this type of inspection. For the in-service inspection of tube bundles the chapter relates the authors' experiences on the ultrasonic inspection of tubes and tube plates in the Prototype Fast Breeder Reactor at Dounreay. At the end of the chapter some comments are made about future ultrasonic and radiographic developments for tube bundles. (author)

  13. 49 CFR 230.61 - Arch tubes, water bar tubes, circulators and thermic siphons.

    Science.gov (United States)

    2010-10-01

    ... MAINTENANCE STANDARDS Boilers and Appurtenances Washing Boilers § 230.61 Arch tubes, water bar tubes, circulators and thermic siphons. (a) Frequency of cleaning. Each time the boiler is washed, arch tubes and... 49 Transportation 4 2010-10-01 2010-10-01 false Arch tubes, water bar tubes, circulators...

  14. Laser initiated endotracheal tube explosion.

    Science.gov (United States)

    De Vane, G G

    1990-06-01

    A 62-year-old male with a diagnosis of subglottic and tracheal stenosis resulting from a prolonged intubation was scheduled for a laser bronchoscopy and placement of a silicon T-shaped tube. His history was significant for two myocardial infarctions, an episode of congestive heart failure and exertional angina. A 6 mm polyvinyl chloride endotracheal tube, wrapped with aluminum tape, was placed in an existing tracheostomy stoma. During the course of the procedure, a sudden bright flash occurred followed by an explosive noise and black smoke rising in the anesthesia circuit and from the patient's mouth. The endotracheal tube was removed and the patient was treated for first and second degree burns in the supraglottic area and base of the tongue. In laser surgery of the airway, special care should be given to reducing the flammability of the inspired gases which can be best accomplished by the mixture of helium with oxygen. Helium acts to retard ignition of polyvinyl chloride tubes in concentrations of 60% or greater. The external surface of the tube can also be protected with the application of a metallic tape affixed in a spiral fashion. Finally, a protocol for the management and treatment of this emergency should be adopted and rehearsed. PMID:2378234

  15. Physics of magnetic flux tubes

    CERN Document Server

    Ryutova, Margarita

    2015-01-01

    This book is the first account of the physics of magnetic flux tubes from their fundamental properties to collective phenomena in an ensembles of flux tubes. The physics of magnetic flux tubes is absolutely vital for understanding fundamental physical processes in the solar atmosphere shaped and governed by magnetic fields. High-resolution and high cadence observations from recent space and  ground-based instruments taken simultaneously at different heights and temperatures not only show the ubiquity of filamentary structure formation but also allow to study how various events are interconnected by system of magnetic flux tubes. The book covers both theory and observations. Theoretical models presented in analytical and phenomenological forms are tailored for practical applications. These are welded with state-of-the-art observations from early decisive ones to the most recent data that open a new phase-space for exploring the Sun and sun-like stars. Concept of magnetic flux tubes is central to various magn...

  16. Analysis of autofrettaged metal tubes

    International Nuclear Information System (INIS)

    Thick-walled cylinders are widely used as compressor cylinders, pump cylinders, high pressure tubing, process reactors and vessels, nuclear reactors, isostatic vessels and gun barrels. In practice, cylinders are generally subjected to sudden and frequently drastic pressure fluctuations, such as the pressure generated in a gun barrel upon the firing of the weapon, pressure reversals in pump cylinders or in process reactors employing high-pressure piping, necessitating enhanced strength of such cylinders. A process for enhancing the strength of thick-walled cylinders has been in service, and is referred to as 'autofrettage'. It extends the service life of the cylinder. The autofrettage is achieved by increasing elastic strength of a cylinder with various methods such as hydraulic pressurization, mechanical swaging, or by utilizing the pressure of a powder gas. This research work deals with the hydraulic and mechanical autofrettage of metal tubes with the objective to attain enhanced strength. Five metal tubes are taken randomly for analysis purpose. The experimental data for five metal tubes is obtained to analyze the behavior of different parameters used during, before, and after autofrettage process. For this research, two-stage autofrettage is taken into consideration. The modeling of the metal tube is carried out in WildFire-ProEngineering, and for analysis purpose, finite element software ANSYS7 and COSMOS are used. The graphical analysis of swage autofrettage is carried out using MATLAB7. The results are validated using available experimental and numerical data. (author)

  17. Thoracoscopic pericardial drainage for gastric tube ulcer penetrated into the pericardium.

    Science.gov (United States)

    Watanabe, Masayuki; Matsuura, Koki; Baba, Hideo; Yoshizumi, Tomoharu; Ikegami, Toru; Soejima, Yuji; Ikeda, Tetsuo; Kawanaka, Hirofumi; Uchiyama, Hideaki; Yamashita, Yo-ichi; Morita, Masaru; Oki, Eiji; Mimori, Koshi; Sugimachi, Keishi; Saeki, Hiroshi; Maehara, Yoshihiko

    2013-10-01

    Peptic ulcer occurring in the gastric conduit for esophageal reconstruction sometimes penetrates into the mediastinal structures. We herein reported a case of pericardial penetration of gastric tube ulcer successfully treated with thoracoscopic pericardial drainage. A 66-year-old Japanese man, who had undergone esophagectomy for esophageal cancer 20 months before, visited our emergency room complaining severe back pain. Computed tomography revealed gastric tube ulcer penetrated into the pericardial space. Thoracoscopic pericardiotomy and drainage was performed and the patient made an uneventful recovery. Thoracoscopic pericardial drainage is useful to manage acute pyogenic pericarditis due to penetration of peptic ulcer which occurred in the gastric tube.

  18. Energy dissipation in circular tube

    Directory of Open Access Journals (Sweden)

    A.D. Girgidov

    2012-01-01

    Full Text Available Energy dissipation distribution along the circular tube radius is important in solving such problems as calculation of heat transfer by the air flow through building envelope; calculation of pressure loss in spiral flows; calculation of cyclones with axial and tangential supply of dust-containing gas.Two types of one-dimensional radially axisymmetric flows in circular tube were considered: axial flow and rotation about the axis (Rankine vortex. Relying on two- and four-layer description of axial turbulent flow energy dissipation was calculated in each layer.Similar calculation for Rankine vortex with viscous sublayer at the tube surface was provided. By employing the dissipation minimum principle the boundary radius between rigid rotation and free vortex is calculated. Approximation of the velocity distribution in Rankine vortex is proposed.

  19. Failure analysis of brass tubes

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence, S.J.; Bodnar, R.L. [Bethlehem Steel Corp., PA (United States)

    1997-02-01

    The 1996 Jacquet Lucas Award for Excellence in Metallography was won by Samuel J. Lawrence and Richard L. Bodnar for their analysis of cracks in Admiralty brass cooling tubes, which are part of a heat exchanger in a turbogenerator that provides electricity to a manufacturing plant. A mixture of non-recirculating city and spring pit water flows through bundles of tubes to cool the oil in which they are immersed. However, a problem developed when several of the brass tubes cracked transversely, allowing cooling water to mix with the oil. This award-winning entry in the ASM/IMS competition shows how the metallographers analyzed the cracks, and what the results were.

  20. Drift tubes of Linac 2

    CERN Multimedia

    1977-01-01

    With the advent of the 800 MeV PS Booster in 1972, the original injector of the PS, a 50 MeV Alvarez-type proton linac, had reached its limits, in terms of intensity and stability. In 1973 one therefore decided to build a new linac (Linac 2), also with a drift-tube Alvarez structure and an energy of 50 MeV. It had a new Cockcroft-Walton preinjector with 750 keV, instead of the previous one with 500 keV. Linac 2 was put into service in 1980. The old Linac 1 was then used for the study of, and later operation with, various types of ions. This picture shows Linac 2 drift-tubes, suspended on stems coming from the top, in contrast to Linac 1, where the drift-tubes stood on stems coming from the bottom.

  1. [The Use of a Tracheal Tube for Guiding Nasogastric Tube Insertion].

    Science.gov (United States)

    Saima, Shunsuke; Asai, Takashi; Okuda, Yasuhisa

    2016-04-01

    An obese patient was scheduled for shoulder joint surgery under general anesthesia. After induction of anesthesia and tracheal intubation, insertion of a gastric tube was difficult. A new tracheal tube was prepared, the connecter was removed, and the tube was cut longitudinally. The tube was inserted orally into the esophagus. A gastric tube was passed through the nose, and its tip was taken out of the mouth. The tip of the gastric tube was passed through the tracheal tube, and its correct position in the stomach was confirmed by auscultation of the epigastrium. The tracheal tube was carefully taken out from the esophagus leaving the gastric tube in the stomach. The cut tracheal tube was peeled off from the gastric tube. Correct positioning of the gastric tube was re-confirmed.

  2. On the welded Tube map

    OpenAIRE

    Audoux, Benjamin

    2014-01-01

    This note investigates the so-called Tube map which connects welded knots, that is a quotient of the virtual knot theory, to ribbon torus-knots, that is a restricted notion of fillable knotted tori in the 4-sphere. It emphasizes the fact that ribbon torus-knots with a given filling are in one-to-one correspondence with welded knots before quotient under classical Reidemeister moves and reformulates these moves and the known sources of non-injectivity of the Tube map in terms of filling changes.

  3. Working session 3: Tubing integrity

    Energy Technology Data Exchange (ETDEWEB)

    Cueto-Felgueroso, C. [Tecnatom, S.A., San Sebastian de los Reyes, Madrid (Spain); Strosnider, J. [NRC, Washington, DC (United States)

    1997-02-01

    Twenty-three individuals representing nine countries (Belgium, Canada, the Czech Republic, France, Japan, the Slovak Republic, Spain, the UK, and the US) participated in the session on tube integrity. These individuals represented utilities, vendors, consultants and regulatory authorities. The major subjects discussed by the group included overall objectives of managing steam generator tube degradation, necessary elements of a steam generator degradation management program, the concept of degradation specific management, structural integrity evaluations, leakage evaluations, and specific degradation mechanisms. The group`s discussions on these subjects, including conclusions and recommendations, are summarized in this article.

  4. Working session 3: Tubing integrity

    International Nuclear Information System (INIS)

    Twenty-three individuals representing nine countries (Belgium, Canada, the Czech Republic, France, Japan, the Slovak Republic, Spain, the UK, and the US) participated in the session on tube integrity. These individuals represented utilities, vendors, consultants and regulatory authorities. The major subjects discussed by the group included overall objectives of managing steam generator tube degradation, necessary elements of a steam generator degradation management program, the concept of degradation specific management, structural integrity evaluations, leakage evaluations, and specific degradation mechanisms. The group's discussions on these subjects, including conclusions and recommendations, are summarized in this article

  5. Orifice plates and venturi tubes

    CERN Document Server

    Reader-Harris, Michael

    2015-01-01

    This book gives the background to differential-pressure flow measurement and goes through the requirements explaining the reason for them. For those who want to use an orifice plate or a Venturi tube the standard ISO 5167 and its associated Technical Reports give the instructions required.  However, they rarely tell the users why they should follow certain instructions.  This book helps users of the ISO standards for orifice plates and Venturi tubes to understand the reasons why the standards are as they are, to apply them effectively, and to understand the consequences of deviations from the standards.

  6. Flow Deflection in Intersected Tubes

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    In order to verify the flow interference at the fracture intersections, a group of hydraulic simulations of crossing flow was carried out. The manifold interference effects at the intersection of fractures on water flow has been confirmed extensively either in the normal or in the oblique intersected tubes as well as in the intersected tubes of either equal or variant diameters. Consequently, suggest that the fissure network can no longer be taken as a set of solitary fractures, but as a set of elementary intersected ractures. The deflection effect at fracture intersections on the water flow should be taken into considwhen is dealt with any theory related to the water migration in fractures.

  7. Application of via-anal ileus tube drainage in the therapy of acute low colorectal obstruction caused by cancer in elderly patients%经肛门肠梗阻导管在老年人急性低位结直肠癌性梗阻治疗中的应用

    Institute of Scientific and Technical Information of China (English)

    石洋; 付文政; 李玉玮; 张锡朋

    2013-01-01

    目的 评价经肛门肠梗阻导管在老年急性低位结直肠癌性梗阻治疗中的应用价值.方法 应用经肛门肠梗阻导管治疗结直肠癌引起的急性低位肠梗阻的老年患者31例.观察患者症状缓解情况、腹围、腹部平片等变化,急性梗阻缓解后,完善术前准备限期手术. 结果 置管减压后,患者急性梗阻症状均有所缓解,后接受限期手术.一期切除根治率93.5%(29/31),一期切除吻合率68.9%(20/31),并发症发生率19.4%(6/31),无围术期死亡.行一期切除吻合患者均未发生吻合口瘘. 结论 经肛门肠梗阻导管用于缓解老年急性低位结直肠癌性梗阻安全、有效、创伤小.有望成为非手术解除急性低位癌性梗阻的首选措施.%Objective To evaluate the role of via-anal ileus tube drainage in the therapy of acute low colorectal obstruction caused by cancer in elderly patients.Methods Totally 31 elderly patients with acute obstruction caused by colorectal cancer were treated by this modality.With the help of colonscopy and radiograph,the ileus tube was inserted into the proximal bowel of the obstructive side via anus.Then we irrigated and drain through the tube.At the same time we observed the patients' symptoms,abdominal girth,plain abdominal radiograph.After the relief of the acute obstruction,operations were processed.Results After 7-14 days treatment,the acute obstruction was relieved and emergency operation was avoided.The cure rate of 1-staged resection was 93.5% (29/31),the rate of 1-staged anastomosis was 68.9% (20/29),the rate of complication was 19.4% (6/31),no anastomotic leakage and no perioperative death occurred.Conclusions The via-anal tube drainage in the treatment of the elderly patients with acute obstruction is safe,effective,and the trauma is small.It would be the first choice to relieve the acute obstruction in future.

  8. X-ray Diagnosis of Pathology in Uterus and Fallopian Tube about 168 Barren Women%不孕症子宫病变168例X线分析

    Institute of Scientific and Technical Information of China (English)

    龙卫华; 范彦伟; 王小红

    2004-01-01

    目的分析不孕妇女子宫病变的X线造影征象,评价造影检查对本病的诊断价值.方法回顾分析168例不孕妇女子宫输卵管碘油造影的影像资料,分析其影像特征.结果168例患者中,正常子宫输卵管影像47例,占28%;双子宫21例,占12.5%;单角子宫5例,占3%;纵隔子宫4例,占2.4%;幼稚子宫3例,占1.8%;子宫内膜结核19例,占11.3%;子宫内膜炎52例,占31%;宫腔粘连17例,占10%.结论子宫输卵管造影对确定不孕妇女的子宫病变的原因有重要的诊断价值.

  9. Aspectos positivos e negativos da esterilização tubária do ponto de vista de mulheres esterilizadas Positive and negative aspects of Fallopian tube sterilization as viewed by sterilized women

    Directory of Open Access Journals (Sweden)

    Luzinete Simões Minella

    1998-01-01

    Full Text Available O objetivo deste artigo consiste em tratar os aspectos positivos e negativos da esterilização feminina, de acordo com o ponto de vista de dois grupos de mulheres esterilizadas em Florianópolis, Santa Catarina, Brasil, a partir de uma discussão sociológica sobre o seu estado de saúde atual, avaliando-se as relações que costumam fazer entre este estado e a condição de esterilizada. O primeiro grupo está constituído por mulheres provenientes de um bairro de baixa renda, predominantemente donas de casa, e o segundo grupo inclui funcionárias públicas, estudantes e professoras universitárias, provenientes dos setores médios da sociedade, totalizando quarenta mulheres. A metodologia da pesquisa baseou-se em um questionário estruturado com perguntas abertas de modo a registrar tanto aspectos ligados a variáveis sócio-econômicas e demográficas, quanto dados subjetivos ligados às representações das mulheres sobre o período pós-esterilização. Além de uma série de outros aspectos, tornou-se possível concluir que não existe consenso sobre as conseqüências da esterilização, tendo-se constatado a existência de uma proporção significativa de mulheres esterilizadas (11 principalmente antes dos 30 anos que percebem alterações de saúde após a laqueadura.The objective of this paper is to point out the positive and negative aspects of female sterilization as seen by two groups of sterilized women in Florianópolis, Santa Catarina, Brazil, based on a sociological discussion of their present health status, evaluating the associations that they generally make with the fact that they have been sterilized. The first group included mostly housewives from a low-income neighborhood, while the second involved upper-middle-class female public employees, students, and university professors, totaling 40 women. Data were obtained through a structured questionnaire with open-ended questions. Information on social, economic, and demographic variables was recorded, along with subjective data associated with women's representations of the post-sterilization period. We concluded that there was no consensus as to the consequences of sterilization, since a number of the women (11/40, mostly sterilized before the age of 30, perceived changes in their health status after surgery.

  10. Paraneoplastic cerebellar degeneration as initial presentation of papillary carcinoma of the fallopian tube: Evaluation and usefulness of {sup 18}F FDG PET/CT. Case report and literature review

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, Nayelli Ortega; Gonzalez, Digna Pachuca; Garcla, Jose Alfonso Rumoroso; Reyna, Juan Carlos Garcia; Lopez, Luis Feilpe Alva [Division of Nuclear Medicine, Mexico City Univ., Mexico City (Mexico)

    2012-03-15

    The acquisition of an {sup 18}F FDG PET/CT scan in patients with suspected paraneoplastic cerebellar syndrome can be helpful in determining the origin of a neoplasm because of its high sensitivity and also helps guide the neurological development course depending on the degree of incorporation of {sup 18}F FDG to the cerebellar parenchyma when compared with the rest of the brain. The {sup 18}F FDG whole body PET-CT (positron emission tomography and computed tomography) scan is a useful tool to determine the origin of a possible paraneoplastic cerebellar degeneration in patients suspected of having malignancy. In this case report, we describe the usefulness of the {sup 18}F fluorodeoxyglucose (FDG) PET CT scan to evaluate the possible presence of PCD, determine the current status of the disease, and find its possible origin.

  11. 库克导丝介入治疗输卵管阻塞性不孕症156例临床分析%Clinical analysis of 156 cases of fallopian tube obstruction infertility treated by Cook guide wire

    Institute of Scientific and Technical Information of China (English)

    李勇奇; 崔青阳; 阿里哈尔; 宋轶凡

    2016-01-01

    目的 对库克导丝治疗输卵管阻塞性不孕的患者进行临床分析.方法 选取我院在2013年6月至2015年1月收治的156例输卵管阻塞性不孕患者作为研究对象,所有患者均经子宫输卵管造影联合Cook导丝进行治疗,并进行12个月的随访.结果 经子宫输卵管造影联合Cook导丝进行治疗后,疏通率为96.79%,5例患者的输卵管未疏通,未疏通率为3.21%;在术后12个月的随访中,宫内的妊娠率为47.02%,有10例患者输卵管妊娠,输卵管的妊娠率为6.62%.结论 输卵管阻塞性不孕患者经子宫输卵管造影联合cook导丝进行治疗,输卵管再通率十分高,值得临床推广.

  12. 大肠癌术后早期胃管拔出对患者血浆降钙素原变化及对胃肠功能恢复的影响%Research on influence of early gastric tube extubation on plasma procalcitonin change and gastrointestinal function recov-ery after colorectal cancer operation

    Institute of Scientific and Technical Information of China (English)

    牟亚刚; 王建军; 张洪伟

    2015-01-01

    目的:探讨大肠癌术后早期胃管拔出对患者血浆降钙素原变化及对胃肠功能恢复的影响。方法选取2010年2月至2014年8月西电集团医院普外科肿瘤科收治的大肠癌术后患者110例,采用随机数表法分为2组,其中研究组55例,予术后早期胃管拔出治疗,术后6 h 开始饮水,12 h 进流食,3 d 过渡到普通饮食;对照组55例,采取常规胃管拔出治疗,术后排气排便后拔出胃管,开始进食。比较术后及干预前后治疗前血浆降钙素原水平及术后并发症情况、术后排气排便时间、住院时间、住院费用等观察指标。结果(1)治疗后2组血浆降钙素原均明显下降,但二者相比差异无统计学意义( P >0.05);(2)治疗后,研究组排气时间(50.71±6.25)h 、排便时间(66.43±5.87)h 、住院时间(7.17±2.31)d 及住院费用(41562.87±274.36)元低于对照组(65.24±6.58)h 、(74.56±5.69)h 、(10.24±3.15)d 、(47893.57±314.82)元,差异有统计学意义(P<0.05);(3)治疗后,研究组并发症发生率(9.09%)与对照组(7.27%)相近,差异无统计学意义(P >0.05)。结论大肠癌术后早期胃管拔出有利于患者促进胃肠功能恢复,缩短住院时间,同时不影响降钙素原水平,不增加并发症发生风险,值得临床推广。%Objective To investigate the curative effect of early gastric tube extubation by observing the chan‐ges the plasma procalcitonin and gastrointestinal function in the colorectal cancer patients with early postoperative gastric tube extubation .Methods 110 postoperative patients with colorectal cancer admitted in the general depart‐ment of Xidian Group Hospital from February 2009 to August 2014 were selected and divided into 2 groups according to the random number table .The observation group(55 cases) was performed the early

  13. Tubo gástrico isoperistáltico de grande curvatura gástrica com sutura mecânica no tratamento cirúrgico do câncer de esôfago irressecável Gastric tube of greater gastric curvature with stapler in surgical treatment of non resectable esophageal cancer

    Directory of Open Access Journals (Sweden)

    José Luis Braga de Aquino

    2009-09-01

    Full Text Available RACIONAL: Frequentemente, o diagnóstico da neoplasia do esôfago é tardio, restando como escolha terapêutica o tratamento paliativo. A transposição de tubo isoperistáltico da grande curvatura gástrica é um dos métodos de eleição que, porém, quando complicado com a deiscência da anastomose, impede a alimentação natural, comprometendo a qualidade de vida. OBJETIVO: Avaliar as complicações da anastomose esofagogástrica cervical com sutura mecânica com o tubo gástrico, em pacientes com câncer de esôfago irressecável. MÉTODO: Vinte e dois pacientes com câncer de esôfago irressecável foram submetidos à transposição do tubo gástrico isoperistáltico. A anastomose com o coto esofágico foi realizada com sutura mecânica circular em nível cervical. Foram avaliadas complicações sistêmicas (cardiopulmonares e locais (a deiscência e a estenose da anastomose esofagogástrica cervical. RESULTADOS: Dez pacientes (45,5% apresentaram de uma a três complicações, dos quais seis (27,2% com complicações sistêmicas: um (4,5% embolia pulmonar (evoluindo ao óbito, um infarto do miocárdio e quatro (18,2% com infecção de pulmão (todos com boa evolução com o tratamento clínico. Cinco pacientes tiveram complicações locais: três (13,6% com deiscência da anastomose e quatro (18,2% com estenose da anastomose, sendo que dois deles tiveram deiscência prévia. De 20 pacientes avaliados em período de seis a 18 meses, 16 (80% apresentaram deglutição satisfatória para sólidos e/ou pastosos. CONCLUSÃO: O tubo gástrico isoperistáltico de grande curvatura, com sutura mecânica, parece oferecer melhora significativa da deglutição com qualidade de vida satisfatória e morbimortalidade aceitável.BACKGROUND: The diagnose of esophageal cancer is in general done clinically late, remaining the palliative treatment the only possibility to improve the quality of life. The isoperistaltic gastric tube transposition may be used

  14. Feasibility and safety study of no setting gastric tube and early drinking water for post-operative patients with distal gastric cancer radical gastrectomy%远端胃癌根治术后不置胃管及早饮水的可行性和安全性研究

    Institute of Scientific and Technical Information of China (English)

    邱兰; 印义琼; 文曰; 卢春燕

    2014-01-01

    Objective To study the feasibility and safety of no setting gastric tube and early drinking water for post-operative patients with distal gastric cancer radical gastrectomy .Method 100 post-operative patients with distal gastric cancer radical gastrectomy was randomly divided into control group and observation group according to the operation order ,50 patients in the control group received routine postoperative care ,placed stomach ,fasting , drinking and keeping the stomach exhaust pipe to the anus after defecation eating water .Patients in observation group received routine nursing ,did not place the tube ,but did drinking warm water 10~20 ml for every four hours under the guidance of doctors 6 hours after the patient fully awake from anesthesia ,The post-operative intestinal function recovery time ,ambulation ,bloating ,respiratory infections ,anastomotic leakage and other factors were ob-served and analyzed between two groups .Result The post-operative intestinal function recovery time and bed time in observation group was shorter .There was significant difference compared with control group (P0 .05) .Conclusion No setting gastric tube and early drinking water for post-operative patients with distal gastric cancer radical gastrectomy was feasible and safe ..It can promote the recovery of bowel function ,postoperative rehabilitation and reduce postoperative com-plications .%目的:探讨远端胃癌根治术后不置胃管及早饮水的安全性和可行性。方法将100例行远端胃癌根治术的患者根据手术先后顺序随机分为对照组和观察组各50例。对照组采用外科术后护理常规,予以安置胃管,禁食、禁饮,保留胃管至肛门排气、排便后再进食水;观察组除外科护理常规外,不安置胃管,术后6h患者麻醉完全清醒后,在医生指导下协助患者每4h饮一次温开水,每次10~20ml,对两组患者术后肠功能恢复时间、下床活动时间、腹胀、呼吸道感染

  15. 21 CFR 876.5980 - Gastrointestinal tube and accessories.

    Science.gov (United States)

    2010-04-01

    ... intubation, feeding tube, gastroenterostomy tube, Levine tube, nasogastric tube, single lumen tube with... § 876.9. (2) Class I (general controls) for the dissolvable nasogastric feed tube guide for the nasogastric tube. The class I device is exempt from the premarket notification procedures in subpart E of...

  16. Panitumumab and pegylated liposomal doxorubicin in platinum-resistant epithelial ovarian cancer with KRAS wild-type

    DEFF Research Database (Denmark)

    Steffensen, Karina Dahl; Waldstrøm, Marianne; Pallisgård, Niels;

    2013-01-01

    OBJECTIVE: The increasing number of negative trials for ovarian cancer treatment has prompted an evaluation of new biologic agents, which in combination with chemotherapy may improve survival. The aim of this study was to investigate the response rate in platinum-resistant, KRAS wild-type ovarian...... cancer patients treated with pegylated liposomal doxorubicin (PLD) supplemented with panitumumab. PATIENTS AND METHODS: Major eligibility criteria were relapsed ovarian/fallopian/peritoneal cancer patients with platinum-resistant disease, measurable disease by GCIG CA125 criteria and KRAS wild-type......-free and overall survival in the intention-to-treat population was 2.7 months (2.5-3.2 months, 95% confidence interval) and 8.1 months (5.6-11.7 months, 95% confidence interval), respectively. The most common treatment-related grade 3 toxicities included skin toxicity (42%), fatigue (19%), and vomiting (12...

  17. Welding the CNGS decay tube

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    3.6 km of welds were required for the 1 km long CERN Neutrinos to Gran Sasso (CNGS) decay tube, in which particles produced in the collision with a proton and a graphite target will decay into muons and muon neutrinos. Four highly skilled welders performed this delicate task.

  18. Fin-tube solar collectors

    Science.gov (United States)

    1980-01-01

    Report presents test procedures and results of thermal-performance evaluation of seven commercial fin tube (liquid) solar collector-absorber plates. Tests were conducted indoors at Marshall Space Flight Center Solar simulator. Results are graphically shown along with supporting test data and summary, indicating efficiency as function of collector inlet temperature.

  19. Working session 1: Tubing degradation

    Energy Technology Data Exchange (ETDEWEB)

    Kharshafdjian, G. [Atomic Energy of Canada, Mississauga, Ontario (Canada); Turluer, G. [IPSN, Fontenay-aux-Roses (France)

    1997-02-01

    A general introductory overview of the purpose of the group and the general subject area of SG tubing degradation was given by the facilitator. The purpose of the session was described as to {open_quotes}develop conclusions and proposals on regulatory and technical needs required to deal with the issues of SG tubing degradation.{close_quotes} Types, locations and characteristics of tubing degradation in steam generators were briefly reviewed. The well-known synergistic effects of materials, environment, and stress and strain/strain rate, subsequently referred to by the acronym {open_quotes}MESS{close_quotes} by some of the group members, were noted. The element of time (i.e., evolution of these variables with time) was emphasized. It was also suggested that the group might want to consider the related topics of inspection capabilities, operational variables, degradation remedies, and validity of test data, and some background information in these areas was provided. The presentation given by Peter Millet during the Plenary Session was reviewed; Specifically, the chemical aspects and the degradation from the secondary side of the steam generator were noted. The main issues discussed during the October 1995 EPRI meeting on secondary side corrosion were reported, and a listing of the potential SG tube degradations was provided and discussed.

  20. Oscillatory flow in bifurcating tubes

    International Nuclear Information System (INIS)

    Respiratory fluid mechanics is characterized by flow through bifurcating, Y-shaped, tubes. Steady flow through such geometries has been studied in detail by several authors. However, the recent widespread use of high frequency mechanical assistance of ventilation has generated interest in unsteady flows. A symmetric, singly branching pipe has been constructed, with its bifurcation shaped to model pulmonary conditions. The form of the bifurcation is based on CAT scans of human tracheal carinas. Its features include an area change of the parent tube from circular to roughly elliptical near the junction, a pinch-off effect on the parent tube, smoothly curved outer walls at the junction, and a sharp flow divider. Parent and daughter tubes have an l/d ratio of > 50, so that entrance effects are avoided. In order to better understand the effects of unsteadiness, piston driven, laminar, purely oscillatory flow has been established in the pipe for a variety of Womersley numbers. By appropriate choices of flow frequency and amplitude, fluid viscosity, and pipe diameter, tracheal Reynolds and Womersley numbers have been matched for resting breathing (tidal volume of 600 ml to 0.25 Hz), high frequency breathing (50 ml at 5 Hz), and intermediate breathing levels

  1. OurTube / David Talbot

    Index Scriptorium Estoniae

    Talbot, David

    2009-01-01

    USA California Ülikooli töötajate Abram Stern'i ja Michael Dale'i poolt 2005. a. algatatud USA kongressis peetud kõnede videoremiksidest ja nende poolt loodud veebisaidist Metavid.org. Ka YouTube keskkonnast ja wikipedia katsetustest muuta oma keskkond multimeedialisemaks

  2. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Supported by the NEI Research at NEI All Research at NEI Office of the Scientific Director Office of the Clinical Director Education Programs ... Health Information News and Events Grants and Funding Research at NEI Education ... NEI YouTube Videos: Amblyopia NEI ...

  3. X-ray tube arrangement

    International Nuclear Information System (INIS)

    An x-ray tube is described incorporating an elongated target/ anode over which the electron beam is deflected and from which x-rays are emitted. Improved methods of monitoring and controlling the amplitude of the beam deflection are presented. (U.K.)

  4. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Macular Degeneration Amblyopia Animations Blindness Cataract Convergence Insufficiency Diabetic Eye Disease Dilated Eye Exam Dry Eye For Kids Glaucoma Healthy Vision Tips Leber Congenital Amaurosis Low Vision Refractive Errors Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube ...

  5. Structure and growth thermodynamics of carbon tubes

    Institute of Scientific and Technical Information of China (English)

    李文治; 钱露茜; 钱生法; 周维亚; 王刚; 付春生; 赵日安; 解思深

    1996-01-01

    Carbon tubes were prepared by Ni (or Ti) catalytic pyrolysis of acetylene. The catalytic effect of nanometer nickel powders is related to the reduction temperature in H2 atmosphere. Nanometer nickel powders reduced at high temperature have a distinguished catalytic effect, and the yield of the carbon tubes is relatively high; but for the nickel powders reduced at low temperature, the yield of carbon tubes is low, and no tube can be formed. Carbon tubes can only be grown along the edges or on the tips of the Ni (or Ti) sheets reduced at about 770C. But if Ni (or Ti) sheets are etched in acid, at lot of carbon tubes with various forms can be formed on their surface. The structure and morphology of the carbon tubes is studied, and the growth thermodynamics for the straight, curved and helical carbon tubes are systematically investigated for the first time.

  6. Ultrasonic testing of steam generator tubes

    International Nuclear Information System (INIS)

    A system is developed for inspection of steam generator tube, especially near the tube plate. Imaging, thickness measurement, radial profilometry, longitudinal and circonferential crack detection and welded joints testing are reviewed

  7. Chemical cleaning specification: few tube test model

    International Nuclear Information System (INIS)

    The specification is for the waterside chemical cleaning of the 2 1/4 Cr - 1 Mo steel steam generator tubes. It describes the reagents and conditions for post-chemical cleaning passivation of the evaporator tubes

  8. Dynamics Calculation of Travel Wave Tube

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    During the dynamics calculating of the travel tube, we must obtain the field map in the tube. The field map can be affected by not only the beam loading, but also the attenuation coefficient. The calculation of the attenuation coefficient

  9. Stages of Urethral Cancer

    Science.gov (United States)

    ... The surgeon may use part of the small intestine to make a tube that passes urine through an opening ( stoma ). This is called an ostomy or urostomy . If ... surgeon may also use part of the small intestine to make a new storage pouch ( continent ... the urine through a stoma. Even if the doctor removes all the cancer ...

  10. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... before cancer How you respond to treatment Seeking Information About Your Prognosis Is a Personal Decision When ... Twitter Instagram YouTube Google+ LinkedIn GovDelivery RSS CONTACT INFORMATION Contact Us LiveHelp Online Chat MORE INFORMATION About ...

  11. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... during a certain period of time after diagnosis. Disease-free survival This statistic is the percentage of ... on YouTube. Barbara’s attitude since her diagnosis with pancreatic cancer? No doctor is going to tell her ...

  12. Tube morphogenesis: closure, but many openings remain

    OpenAIRE

    Nelson, W. James

    2003-01-01

    Epithelial and endothelial tubes form the basic structure of many organs and tissues in the fruit fly Drosophila melanogaster, the nematode Caenorhabditis elegans, zebrafish and mammals. Comparison of how tubes form during development defines several pathways that generate a single unbranched tube or dichotomously branching tubular networks. The formation of tubes can be induced directly by intrinsic signals within epithelial primordia or by inductive signaling between adjacent epithelia and ...

  13. Tube Thoracostomy: Complications and Its Management

    OpenAIRE

    Chinenye Kesieme; Eshiobo Irekpita; Nze Jebbin; Ndubueze Ezemba; Andrew Dongo; Kesieme, Emeka B.

    2011-01-01

    Background. Tube thoracostomy is widely used throughout the medical, surgical, and critical care specialities. It is generally used to drain pleural collections either as elective or emergency. Complications resulting from tube thoracostomy can occasionally be life threatening. Aim. To present an update on the complications and management of complications of tube thoracostomy. Methods. A review of the publications obtained from Medline search, medical libraries, and Google on tube thoracostom...

  14. [A tube retractor for cardiac surgery].

    Science.gov (United States)

    Ohkado, A; Shiikawa, A; Ishitoya, H; Murata, A

    2001-03-01

    A retractor exclusively used to retract the tubes in cardiac surgery which needs cardiopulmonary bypass was developed. The half-cylinder-shaped end, the lightly curved handle and the flat and triangular grip enable easy and effective grasp of the tubes. This new instrument facilitates operative procedures by effectively retracting the tubes which persistently obstruct the operative field, in such a case of placement of a retrograde cardioplegia tube via the right atrium.

  15. Kundt's Tube: An Acoustic Gas Analyzer

    Science.gov (United States)

    Aristov, Natasha; Habekost, Gehsa; Habekost, Achim

    2011-01-01

    A Kundt tube is normally used to measure the speed of sound in gases. Therefore, from known speeds of sound, a Kundt tube can be used to identify gases and their fractions in mixtures. In these experiments, the speed of sound is determined by measuring the frequency of a standing sound wave at a fixed tube length, temperature, and pressure. This…

  16. Feasibility of Upper Port Plug tube handling

    NARCIS (Netherlands)

    Koning, J. F.; Elzendorn, B. S.; Ronden, D. M. S.; Klinkhamer, J. F. F.; Biel, W.; Krasikov, Y.; Walker, C. I.

    2011-01-01

    Central, retractable tubes are proposed in several Upper Port Plugs (UPPs) designs for ITER, to enable fast exchange of specific components of diagnostics housed in these UPPs. This paper investigates into possible designs to enable the efficient handling of tubes. The feasibility of tube handling i

  17. Welding device inside a small diameter tube

    International Nuclear Information System (INIS)

    The orbital welding tool is supported in a socket at the end of a flexible tube. A motor rotating the head is placed in a casing fixed to the other end of the flexible tube and rotates the welding tool by the intermediary of a flexible transmission. A second flexible tube fixed to the casing permits the translation of the welding tool

  18. The comparison of corrosion resistance between Baosteel's alloy 690 tube and foreign alloy 690 tube

    International Nuclear Information System (INIS)

    Alloy 690 having excellent corrosion resistance is widely used for SG tubes. The intergranular corrosion and pitting corrosion resistance of Baosteel's alloy 690 tube, Country A alloy 690 tube and Country B alloy 690 tube have been analysed by comparison. It shows that: The intergranular corrosion of Baosteel's alloy 690 tube tested complied with ASTM G28 Standard could satisfy the technical requirement. However.some of Baosteel's alloy 690 tube in intergranular corrosion resistance had less performance than Country A. In addition, pitting corrosion tested with ASTM G48 Standard shown the Baosteel's alloy 690 tube better than Country B. (authors)

  19. Mechanical Instabilities of Biological Tubes

    CERN Document Server

    Hannezo, Edouard; Prost, Jacques; 10.1103/PhysRevLett.109.018101

    2012-01-01

    We study theoretically the shapes of biological tubes affected by various pathologies. When epithelial cells grow at an uncontrolled rate, the negative tension produced by their division provokes a buckling instability. Several shapes are investigated : varicose, enlarged, sinusoidal or sausage-like, all of which are found in pathologies of tracheal, renal tubes or arteries. The final shape depends crucially on the mechanical parameters of the tissues : Young modulus, wall-to-lumen ratio, homeostatic pressure. We argue that since tissues must be in quasistatic mechanical equilibrium, abnormal shapes convey information as to what causes the pathology. We calculate a phase diagram of tubular instabilities which could be a helpful guide for investigating the underlying genetic regulation.

  20. HIGH CURRENT COAXIAL PHOTOMULTIPLIER TUBE

    Science.gov (United States)

    Glass, N.W.

    1960-01-19

    A medium-gain photomultiplier tube having high current output, fast rise- time, and matched output impedance was developed. The photomultiplier tube comprises an elongated cylindrical envelope, a cylindrical anode supported at the axis of the envelope, a plurality of elongated spaced opaque areas on the envelope, and a plurality of light admitting windows. A photo-cathode is supported adjacent to each of the windows, and a plurality of secondary emissive dynodes are arranged in two types of radial arrays which are alternately positioned to fill the annular space between the anode and the envelope. The dynodes are in an array being radially staggered with respect to the dynodes in the adjacent array, the dynodes each having a portion arranged at an angle with respect to the electron path, such that electrons emitted by each cathode undergo multiplication upon impingement on a dynode and redirected flight to the next adjacent dynode.

  1. Scintillation counter: photomultiplier tube alignment

    International Nuclear Information System (INIS)

    A scintillation counter, particularly for counting gamma ray photons, includes a massive lead radiation shield surrounding a sample-receiving zone. The shield is disassembleable into a plurality of segments to allow facile installation and removal of a photomultiplier tube assembly, the segments being so constructed as to prevent straight-line access of external radiation through the shield into the sample receiving zone. Provisions are made for accurately aligning the photomultiplier tube with respect to one or more sample-transmitting bores extending through the shield to the sample receiving zone. A sample elevator, used in transporting samples into the zone, is designed to provide a maximum gamma-receiving aspect to maximize the gamma detecting efficiency. (auth)

  2. Ionization tube simmer current circuit

    Science.gov (United States)

    Steinkraus, Jr., Robert F.

    1994-01-01

    A highly efficient flash lamp simmer current circuit utilizes a fifty percent duty cycle square wave pulse generator to pass a current over a current limiting inductor to a full wave rectifier. The DC output of the rectifier is then passed over a voltage smoothing capacitor through a reverse current blocking diode to a flash lamp tube to sustain ionization in the tube between discharges via a small simmer current. An alternate embodiment of the circuit combines the pulse generator and inductor in the form of an FET off line square wave generator with an impedance limited step up output transformer which is then applied to the full wave rectifier as before to yield a similar simmer current.

  3. Microstructural degradation in compound tubes

    Energy Technology Data Exchange (ETDEWEB)

    Salonen, J.; Auerkari, P. [VTT Manufacturing Technology, Espoo (Finland)

    1996-12-31

    In order to quantify microstructural degradation at high temperatures, samples of SA 210 / AISI 304 L compound tube material were annealed in the temperature range 540-720 deg C for 1 to 1 000 hours. The hardness of the annealed material was measured and the micro structure of the samples was investigated with optical and scanning electron microscopy. Microstructural degradation was characterised by the carbide structure in the ferritic-pearlitic base material and by the depth of decarburised and carburised zones of the compound tube interface. The observed changes were quantified in terms of their time and temperature dependence and diffusion coefficients of the process. The results can be used in estimating the extent of thermal exposure of high-temperature components after long-term service or after incidences of overheating. (orig.) (4 refs.)

  4. Flux tubes at Finite Temperature

    CERN Document Server

    Bicudo, Pedro; Cardoso, Marco

    2016-01-01

    We show the flux tubes produced by static quark-antiquark, quark-quark and quark-gluon charges at finite temperature. The sources are placed in the lattice with fundamental and adjoint Polyakov loops. We compute the square densities of the chromomagnetic and chromoelectric fields above and below the phase transition. Our results are gauge invariant and produced in pure gauge SU(3). The codes are written in CUDA and the computations are performed with GPUs.

  5. Ultrasonic inspection of inpile tubes

    International Nuclear Information System (INIS)

    The in-service inspection (ISI) of inpile tubes can be performed accurately and safely with a semiautomatic ultrasonic inspection system. The ultrasonic technique uses a set of multiple transducers to detect and size cracks, voids, and laminations radially and circumferentially. Welds are also inspected for defects. The system is designed to inspect stainless steel and Inconel tubes ranging from 53.8 mm (2.12 in.) to 101.6 mm (4 in.) inner diameter with wall thickness on the order of 5 mm. The inspection head contains seven transducers mounted in a surface-following device. Six angle-beam transducers generate shear waves in the tubes. Two of the six are oriented to detect circumferential cracks, and two detect axial cracks. Although each of these four transducers is used in the pulse-echo mode, they are oriented in aligned sets so pitch-catch operation is possible if desired. The remaining angle-beam transducers are angulated to detect flaws that are off axial or circumferential orientation. The seventh transducer is used for longitudinal inspection and detects and sizes laminar-type defects

  6. Preparation of chitosan nanofiber tube by electrospinning.

    Science.gov (United States)

    Matsuda, Atsushi; Kagata, Go; Kino, Rikako; Tanaka, Junzo

    2007-03-01

    Water-insoluble chitosan nanofiber sheets and tubes coated with chitosan-cast film were prepared by electrospinning. When as-spun chitosan nanofiber sheets and tubes were immersed in 28% ammonium aqueous solution, they became insoluble in water and showed nanofiber structures confirmed by SEM micrography. Mechanical properties of chitosan nanofiber sheets and tubes were improved by coating with chitosan-cast film, which gave them a compressive strength higher than that of crab-tendon chitosan, demonstrating that chitosan nanofiber tubes coated with chitosan-cast film are usable as nerve-regenerative guide tubes.

  7. Turbine nozzle stage having thermocouple guide tube

    Science.gov (United States)

    Schotsch, Margaret Jones; Kirkpatrick, Francis Lawrence; Lapine, Eric Michael

    2002-01-01

    A guide tube is fixed adjacent opposite ends in outer and inner covers of a nozzle stage segment. The guide tube is serpentine in shape between the outer and inner covers and extends through a nozzle vane. An insert is disposed in the nozzle vane and has apertures to accommodate serpentine portions of the guide tube. Cooling steam is also supplied through chambers of the insert on opposite sides of a central insert chamber containing the guide tube. The opposite ends of the guide tube are fixed to sleeves, in turn fixed to the outer and inner covers.

  8. Development boiling to sprinkled tube bundle

    Science.gov (United States)

    Kracík, Petr; Pospíšil, Jiří

    2016-03-01

    This paper presents results of a studied heat transfer coefficient at the surface of a sprinkled tube bundle where boiling occurs. Research in the area of sprinkled exchangers can be divided into two major parts. The first part is research on heat transfer and determination of the heat transfer coefficient at sprinkled tube bundles for various liquids, whether boiling or not. The second part is testing of sprinkle modes for various tube diameters, tube pitches and tube materials and determination of individual modes' interface. All results published so far for water as the falling film liquid apply to one to three tubes for which the mentioned relations studied are determined in rigid laboratory conditions defined strictly in advance. The sprinkled tubes were not viewed from the operational perspective where there are more tubes and various modes may occur in different parts with various heat transfer values. The article focuses on these processes. The tube is located in a low-pressure chamber where vacuum is generated using an exhauster via ejector. The tube consists of smooth copper tubes of 12 mm diameter placed horizontally one above another.

  9. Gastroenteric tube feeding: Techniques, problems and solutions

    Science.gov (United States)

    Blumenstein, Irina; Shastri, Yogesh M; Stein, Jürgen

    2014-01-01

    Gastroenteric tube feeding plays a major role in the management of patients with poor voluntary intake, chronic neurological or mechanical dysphagia or gut dysfunction, and patients who are critically ill. However, despite the benefits and widespread use of enteral tube feeding, some patients experience complications. This review aims to discuss and compare current knowledge regarding the clinical application of enteral tube feeding, together with associated complications and special aspects. We conducted an extensive literature search on PubMed, Embase and Medline using index terms relating to enteral access, enteral feeding/nutrition, tube feeding, percutaneous endoscopic gastrostomy/jejunostomy, endoscopic nasoenteric tube, nasogastric tube, and refeeding syndrome. The literature showed common routes of enteral access to include nasoenteral tube, gastrostomy and jejunostomy, while complications fall into four major categories: mechanical, e.g., tube blockage or removal; gastrointestinal, e.g., diarrhea; infectious e.g., aspiration pneumonia, tube site infection; and metabolic, e.g., refeeding syndrome, hyperglycemia. Although the type and frequency of complications arising from tube feeding vary considerably according to the chosen access route, gastrointestinal complications are without doubt the most common. Complications associated with enteral tube feeding can be reduced by careful observance of guidelines, including those related to food composition, administration rate, portion size, food temperature and patient supervision. PMID:25024606

  10. Gastroenteric tube feeding: techniques, problems and solutions.

    Science.gov (United States)

    Blumenstein, Irina; Shastri, Yogesh M; Stein, Jürgen

    2014-07-14

    Gastroenteric tube feeding plays a major role in the management of patients with poor voluntary intake, chronic neurological or mechanical dysphagia or gut dysfunction, and patients who are critically ill. However, despite the benefits and widespread use of enteral tube feeding, some patients experience complications. This review aims to discuss and compare current knowledge regarding the clinical application of enteral tube feeding, together with associated complications and special aspects. We conducted an extensive literature search on PubMed, Embase and Medline using index terms relating to enteral access, enteral feeding/nutrition, tube feeding, percutaneous endoscopic gastrostomy/jejunostomy, endoscopic nasoenteric tube, nasogastric tube, and refeeding syndrome. The literature showed common routes of enteral access to include nasoenteral tube, gastrostomy and jejunostomy, while complications fall into four major categories: mechanical, e.g., tube blockage or removal; gastrointestinal, e.g., diarrhea; infectious e.g., aspiration pneumonia, tube site infection; and metabolic, e.g., refeeding syndrome, hyperglycemia. Although the type and frequency of complications arising from tube feeding vary considerably according to the chosen access route, gastrointestinal complications are without doubt the most common. Complications associated with enteral tube feeding can be reduced by careful observance of guidelines, including those related to food composition, administration rate, portion size, food temperature and patient supervision.

  11. Tube erosion in bubbling fluidized beds

    Energy Technology Data Exchange (ETDEWEB)

    Levy, E.K. [Lehigh Univ., Bethlehem, PA (United States). Energy Research Center; Stallings, J.W. [Electric Power Research Inst., Palo Alto, CA (United States)

    1991-12-31

    This paper reports on experimental and theoretical studies that were preformed of the interaction between bubbles and tubes and tube erosion in fluidized beds. The results are applicable to the erosion of horizontal tubes in the bottom row of a tube bundle in a bubbling bed. Cold model experimental data show that erosion is caused by the impact of bubble wakes on the tubes, with the rate of erosion increasing with the velocity of wake impact with the particle size. Wake impacts resulting from the vertical coalescence of pairs of bubbles directly beneath the tube result in particularly high rates of erosion damage. Theoretical results from a computer simulation of bubbling and erosion show very strong effects of the bed geometry and bubbling conditions on computed rates of erosion. These results show, for example, that the rate of erosion can be very sensitive to the vertical location of the bottom row of tubes with respect to the distributor.

  12. Perforation of a gastric tube peptic ulcer into the thoracic aorta.

    Science.gov (United States)

    Katsoulis, I E; Veloudis, G; Exarchos, D; Yannopoulos, P

    2001-01-01

    We present a case of a 52-year-old male patient who died from massive hematemesis as a result of perforation of a benign peptic ulcer into the descending thoracic aorta, 1 year after esophagectomy for esophageal cancer and gastric tube interposition. We also review the literature for mechanisms of ulceration in intrathoracic gastric grafts and for complications of such ulcers.

  13. Bearing pad to pressure tube contact simulation

    Energy Technology Data Exchange (ETDEWEB)

    Talebi, F.; Behdadi, A.; Luxat, J.C., E-mail: farshat@mcmaster.ca, E-mail: behdada@mcmaster.ca, E-mail: luxatj@mcmaster.ca [McMaster Univ., Dept. of Engineering Physics, Hamilton, Ontario (Canada)

    2011-07-01

    Thermal creep strain deformation is a very important pressure tube failure mechanism. During a postulated LOCA (loss of coolant accident) with failure of emergency core injection sys- tem (ECIS), the fuel cladding temperature rapidly increases and the pressure tube becomes completely dry in a few seconds after flow stagnation occurs. Subsequently, the pressure tube circumference is heated by thermal radiation except at the spots where the bearing pads are in direct contact with the pressure tube. Therefore, the localized hot spots are developed on the pressure tube's inner surface under the bearing pads. The main objective of this paper is to evaluate the local thermal-mechanical deformation of a pressure tube in a CANDU reactor and to investigate the fuel channel integrity under localized contact between bearing pad and pressure tube. Furthermore, the mechanistic models are validated against the experimental works per- formed at WRL (Whiteshell research laboratory). Calculations are performed using the finite element method in which the heat, thermal mechanical and creep strain equations are solved, simultaneously. According to the experimental set up, the heat conduction from bearing pads to the inner surface of the pressure tube with appropriate convective and radiation boundary conditions has been simulated. Furthermore, the thermal creep strain deformation has been obtained for when the pressure tube is still under operational condition. It is observed that the pressure tube thermal strain will occur if sufficient high temperature is reached however, depending on the severity of flow degradation in the fuel channel, these localized hot spots could represent a potential creep strain failure of the pressure tube. Whether the pressure tube would fail at these hot spots before contacting the calandria tube depends on the localized temperature and experienced pressure transients. Sensitivity analysis is performed in order to evaluate the contact conductance

  14. Effect of tube-support interaction on the dynamic responses of heat exchanger tubes. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Y.S.; Jendrzejczyk, J.A.; Wambsganss, M.W.

    1977-01-01

    Operating heat exchangers have experienced tube damages due to excessive flow-induced vibration. The relatively small inherent tube-to-baffle hole clearances associated with manufacturing tolerances in heat exchangers affect the tube vibrational characteristics. In attempting a theoretical analysis, questions arise as to the effects of tube-baffle impacting on dynamic responses. Experiments were performed to determine the effects of tube-baffle impacting in vertical/horizontal tube orientation, and in air/water medium on the vibrational characteristics (resonant frequencies, mode shapes, and damping) and displacement response amplitudes of a seven-span tube model. The tube and support conditions were prototypic, and overall length approximately one-third that of a straight tube segment of the steam generator designed for the CRBR. The test results were compared with the analytical results based on the multispan beam with ''knife-edge'' supports.

  15. Effect of U-tube length on space distribution of UTSG reverse flow in tubes

    International Nuclear Information System (INIS)

    For natural circulation, it is shown that parallel flow in the tubes of inverted U-tube steam generators can be non-uniform. And reverse flow occurs in some tubes. Existing studies on the space distribution of reverse flow tubes are dissident. A flow model of one-dimensional steady state is established. Analysis shows that the length will change the relationship of flow characteristics between tubes. And the space distribution of reverse flow tube differs further. When the U-tube length of UTSG is small enough, flow excursion will occur earlier in shorter tube than longer tube, and vise versa. And the analysis is validated by best estimate code RELAP5/MOD3.3. (authors)

  16. CFD modeling of a boiler's tubes rupture

    International Nuclear Information System (INIS)

    This paper reports the results of a study on the reason for tubes damage in the superheater Platen section of the 320 MW Bisotoun power plant, Iran. The boiler has three types of superheater tubes and the damage occurs in a series of elbows belongs to the long tubes. A three-dimensional modeling was performed using an in-house computational fluid dynamics (CFD) code in order to explore the reason. The code has ability of simultaneous solving of the continuity, the Reynolds-Averaged Navier-Stokes (RANS) equations and employing the turbulence, combustion and radiation models. The whole boiler including; walls, burners, air channels, three types of tubes, etc., was modeled in the real scale. The boiler was meshed into almost 2,000,000 tetrahedral control volumes and the standard k-ε turbulence model and the Rosseland radiation model were used in the model. The theoretical results showed that the inlet 18.9 MPa saturated steam becomes superheated inside the tubes and exit at a pressure of 17.8 MPa. The predicted results showed that the temperature of the steam and tube's wall in the long tubes is higher than the short and medium size tubes. In addition, the predicted steam mass flow rate in the long tube was lower than other ones. Therefore, it was concluded that the main reason for the rupture in the long tubes elbow is changing of the tube's metal microstructure due to working in a temperature higher than the design temperature. In addition, the structural fatigue tension makes the last elbow of the long tube more ready for rupture in comparison with the other places. The concluded result was validated by observations from the photomicrograph of the tube's metal samples taken from the damaged and undamaged sections

  17. Development of INCONEL 600 precision tube (1)

    Energy Technology Data Exchange (ETDEWEB)

    Joo, Yeong Han; Jo, Bong Hyeon; Lee, Dong Hee; Kim, Wan Kyo; Jeong, Pyeong Keun; Yoon, Hwang Lo; Chio, Seok Sik [Sammi Steel Co. Ltd., Changwon (Korea, Republic of)

    1994-07-01

    Steam generator, being connected with nuclear fuel reactor is one of the most important part of nuclear power plant and consists of a large number of INCONEL 600 tubes. Approximately 160 tons of tubes are needed for a single nuclear power plant. All of INCONEL 600 steam generator tubes for domestic nuclear power plants have been imported. The aim of this research is to develop INCONEL 600 precision tubes for steam generator of nuclear power plant. If this research is conducted successfully, we can produce nuclear fuel tubes, Ni-alloy precision tubes and stainless steel precision tubes for many purposes and technology of INCONEL 600 steam generator tubes are similar to those of other tubes above mentioned. In the current study, development of preliminary manufacturing process of INCONEL 600 precision tubes for steam generator and investigation of material`s metallurgical characteristics were conducted. The main scope of this research is as follows. First, the preliminary manufacturing process design was conducted after investigations of foreign manufacturing processes and technical reports. Second, the results of investigations of material`s metallurgical characteristics through the manufacturing process were applied to the production technology of tentative INCONEL 600 precision tubes for sample. Third, preliminary process routes were established and samples of INCONEL 600 precision tube were produced by this process. As the results of this research, 14 pieces of INCONEL 600 precision tubes were produced by preliminary manufacturing process and the material`s metallurgical characteristics were investigated through the processes. But the SCC test could not be conducted due to the absence of equipment. In order to apply the results of SCC test to the manufacturing process, we need a SCC tester which can simulate SCC characteristics under high temperature and high pressurized circulating water. 95 refs., 55 figs., 20 tabs.

  18. Closed End Launch Tube (CELT)

    Science.gov (United States)

    Lueck, Dale E.; Immer, Christopher D.

    2004-02-01

    A small-scale test apparatus has been built and tested for the CELT pneumatic launch assist concept presented at STAIF 2001. The 7.5 cm (3-inch) diameter × 305 M (1000 feet) long system accelerates and pneumatically brakes a 6.35 cm diameter projectile with variable weight (1.5 - 5 Kg). The acceleration and braking tube has been instrumented with optical sensors and pressure transducers at 14 stations to take data throughout the runs. Velocity and pressure profiles for runs with various accelerator pressures and projectile weights are given. This test apparatus can serve as an important experimental tool for verifying this concept.

  19. Steam generator tube laser sleeving

    International Nuclear Information System (INIS)

    For many years, Framatome has been used with different techniques and means to perform the steam generator tube sleeving operation, such as the 'mechanical' either GTAW welded or kinetic welding process. As soon as first power laser units appeared on the market we felt right interested in applying this process to the sleeving operation. After comparison between all the processes and equipments existing at that time (that is to say CO2 and YAG laser units), we chose the YAG and bought a 1.2 kW NEC laser unit in 1988. As it was installed in our Welding Center of Le Creusot, this equipment enabled us carrying out a preliminary test programme which targets were: getting the mastery of the equipment and associated technologies, implementing this process for the sleeve welding operation by improvement of the welding-pen. The NEC laser unit became afterwards transferred to our workshop in Chalon-sur-Saone (June 1990), where we achieved the final tests of the process at the same time we were investigating the development of industrial operation means. The actual program is mainly focused on 7/8'' tube steam generator repair process at tubesheet outlet. Yet made sure that our methods and means apply as well to 3/4'' tubes up to second tube support-plate level. Sleeves are made of heat-treated Inconel 690. The sleeved unit has been designed to provide the same breaking strength and leak-tightness as the tube. The upper part of sleeve consists of an anti-pop out length which ensures some locking-up in case the tube breaks in upper transition expansion area. Preliminary tests dealt with the various parameters which may exert an influence on geometry and quality of the, weld bead, as: - laser beam power (for continuous and pulsed modes), - welding speed, - focal spot size and location from the surface to be welded, - protective gas. After performance of preliminary tests on many thousands of weld beads we decided to use the process according to following criteria: Weld quality

  20. Eddy current inspection of tubing

    International Nuclear Information System (INIS)

    The Experimental research work carried out to develop a Eddy current testing equipment is described. Search coils with ferrite or air cores were used and the obtained results are discussed. Valuable information was gained from a improved channel in which a direct measure of the defect and the reference signal phase difference is obtained. Artificial defect used to evaluate resolution and sensitivity were produced by electro-machining and mechanical means. Finned SAP tubing was tested in a routine basis with the described equipment and the results plotted. Basic and theoretical considerations on the Eddy current testing technique are given in the last section of this report. (Author)

  1. Endoscopically nasojejunal feeding tube placement for enteral nutrition in gastric cancer patients with antrum or pyloric obstruction%胃窦癌伴胃窦腔或幽门梗阻经胃镜放置鼻空肠营养管的临床应用

    Institute of Scientific and Technical Information of China (English)

    曹燕飞; 周辛欣; 季峰

    2012-01-01

    目的 比较胃窦癌伴胃窦腔或幽门梗阻患者经胃镜放置鼻空肠营养管(endoscopically nasojejunal feeding tube placement,ENFTP)行肠内营养(enteral nutrition,EN)与全胃肠外营养(total parenteral nutrition,TPN)的临床疗效.方法 选择胃窦癌伴胃窦腔或幽门梗阻患者行ENFTP的患者共100例,选取同期行TPN治疗的患者50例,分别观察两组在营养支持后1、2周的血红蛋白、血清白蛋白、血脂、体重等营养指标,平均住院天数,营养支持平均每日费用,并发症的发生率及营养支持后能耐受化疗或手术的例数.结果 营养支持后1周,ENFTP组的营养指标无明显变化(均P >0.05).TPN组的血红蛋白、肌酐及体重较治疗前有进一步下降(均P<0.05).营养支持后2周,ENFTP组血清总蛋白及白蛋白较治疗前升高明显(P<0.05),而TPN组在血红蛋白、血肌酐、血清白蛋白较治疗前下降明显,与ENFTP组比差异有统计学意义(P<0.05).两组其他营养指标在营养支持后2周差异无统计学意义(P >0.05).ENFTP组在平均住院日、营养支持平均每日费用、并发症的发生率方面均低于TPN组(P<0.05).ENFTP组与TPN组在营养支持后耐受手术或化疗的例数无明显差异(P >0.05).结论 胃窦癌伴胃窦腔或幽门梗阻患者ENFTP较TPN更能有效的维持或改善其营养状况,并缩短患者的住院天数,减少住院费用,提高患者的生存质量.经胃镜放置空肠营养管在胃窦癌伴胃窦腔或幽门梗阻患者中的使用是简便快捷、安全有效的,值得临床推广.%Objective To evaluate the application of endoscopically nasojejunal feeding tube placement (ENFTP) for enteral nutrition (EN) in gastric cancer patients with antrum or pyloric obstruction. Methods One hundred and fifty gastric cancer patients with antrum or pyloric obstruction received ENFTP EN (n=100) or total parenteral nutrition (TPN, n=50). Hemoglobin, serum albumin, blood lipids, weight and

  2. Disc-retained tubes for radiologically inserted gastrostomy (RIG): Not up to the job?

    International Nuclear Information System (INIS)

    Aim: To assess the insertion procedure and performance of disc-retained gastrostomy tubes, recording complications and accidental displacements by prospective audit, and to determine whether primary placement of the tube off-licence was feasible. Materials and methods: Disc-retained 12 F single-lumen Monarch gastrostomy tubes (Enteral UK, Selby, UK) were inserted by three gastrointestinal interventional radiologists in a supra-regional cancer centre. The 12 F tubes required a 20 F peel-away sheath with four-point gastropexy fixation and were placed under conscious sedation, using electrocardiogram (EEG) bispectral index monitoring. Follow-up was performed in an in-house gastrostomy drop-in clinic at 1 week and 1 month, supplemented with weekly telephone follow-up. Patients also had open access to the gastrostomy drop-in clinic for immediate advice and complication management. Results: Eighteen patients underwent primary insertion of a Monarch gastrostomy tube over 5 months. A total of 6/18 (33%) tubes displaced; 4/18 (22%) completely, 2/18 (11%) occult into the peritoneum. Four of 18 (22%) patients developed infection at the stoma site. Due to the unexpectedly poor performance of the tube, the study was terminated early. Conclusion: Initial experience with the Monarch disc-retained gastrostomy tube demonstrates it unsuitable for primary placement with current protocols. In view of the potentially serious complications, the Medicines and Healthcare Products Regulatory Agency (MHRA) has been informed. A request has been made to the distributer to reassess the tube design and/or review the procedure promoted for primary placement

  3. Successful tubes treatment of esophageal fistula

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Aim: To discuss the merits of "tubes treatment" for esophageal fistula (EF). Methods: A 66-year-old female who suffered from a bronchoesophageal and esophagothoratic fistula underwent a successful "three tubes treatment" (close chest drainage, negative pressure suction at the leak, and nasojejunal feeding tube), combination of antibiotics, antacid drugs and nutritional support. Another 55-year-old male patient developed an esophagopleural fistula (EPF) after esophageal carcinoma operation. He too was treated conservatively with the three tubes strategy as mentioned above towards a favorable outcome. Results:The two patients recovered with the tubes treatment, felt well and became able to eat and drink, presenting no complaint. Conclusion: Tubes treatment is an effective basic way for EF. It may be an alternative treatment option.

  4. Development of a supermirror neutron guide tube

    International Nuclear Information System (INIS)

    A supermirror neutron guide tube with a characteristic wavelength of 1.2 A was developed and installed at the Kyoto University Reactor (KUR). The apparent critical wavelength of the present supermirrors is about 250 A. The geometrical parameters of the guide tube are : 11.7 m total length, and 10 mm wide x 74 mm high beam cross section. The supermirror neutron guide tube presents decisive advantages over the conventional nickel mirror guide tube higher transmission of neutrons, brought about through the contribution of neutrons of shorter wavelengths and of those presenting large divergent angles. The total neutron flux obtained from the KUR supermirror guide tube is about 5 x 107 n/cm2 · s, which is about 25 times what is obtainable with the conventional KUR nickel mirror neutron guide tube of the same geometrical parameters. (author)

  5. Precision alignment of permanent magnet drift tubes

    International Nuclear Information System (INIS)

    The Lawrence Berkeley National Laboratory (LBNL) technique of drift-tube alignment has been resurrected at Los Alamos for the precision alignment of 1-cm-core drift tubes that carry high gradient rare-earth-cobalt quadrupoles. Because the quadrupoles cannot be switched off, this technique is not applicable to a drift-tube assembly, but tests indicate that individual magnetic centers can be detected with a precision of +/-0.003 mm. Methods of transferring this information to machined alignment flats on the sides of the drift-tube body are discussed. With measurements of drift tubes designed for a 100-mA, 425-MHz drift-tube linac, offsets between the geometric and magnetic axes of up to +/-0.05 mm were detected following final assembly and welding. This degree of offset is serious if not accommodated, because it represents the entire alignment tolerance for the 40-cell tank. The measurement equipment and technique are described

  6. Ballooning of CANDU pressure tubes. Model assessment

    International Nuclear Information System (INIS)

    The transient creep equations used to analyze the possible ballooning and failure of Zr-2.5% Nb pressure tubes during a loss-of-coolant accident (LOCA) were developed and verified using as-received Zr-2.5% Nb pressure tube material. But in a CANDU reactor, the pressure tubes absorb deuterium and are exposed to a continuous neutron fluence. Consequently, a literature survey was done to determine how irradiation damage and deuterium might affect the creep rate and ductility of Zr-2.5% Nb pressure tubes in the temperature range from 600 to 800 degrees C. It was found that irradiation damage, dissolved deuterium and deuteride blisters could possibly affect the creep rate and ductility of ZR-2.5% Nb pressure tubes in this temperature range, but deuteride platelets are expected to have little effect. Further tests are required to determine the effect of irradiation damage and deuterium on the creep rate and ductility of pressure tubes

  7. CFD Simulation on Ethylene Furnace Reactor Tubes

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Different mathematical models for ethylene furnace reactor tubes were reviewed. On the basis of these models a new mathematical simulation approach for reactor tubes based on computational fluid dynamics (CFD) technique was presented. This approach took the flow, heat transfer, mass transfer and thermal cracking reactions in the reactor tubes into consideration. The coupled reactor model was solved with the SIMPLE algorithm. Some detailed information about the flow field, temperature field and concentration distribution in the reactor tubes was obtained, revealing the basic characteristics of the hydrodynamic phenomena and reaction behavior in the reactor tubes. The CFD approach provides the necessary information for conclusive decisions regarding the production optimization, the design and improvement of reactor tubes, and the new techniques implementation.

  8. Narratives From YouTube

    Directory of Open Access Journals (Sweden)

    Mikael Quennerstedt

    2013-10-01

    Full Text Available The aim of this paper is to explore what is performed in students’ and teachers’ actions in physical education practice in terms of “didactic irritations,” through an analysis of YouTube clips from 285 PE lessons from 27 different countries. Didactic irritations are occurrences that Rønholt describes as those demanding “didactic, pedagogical reflections and discussions, which in turn could lead to alternative thinking and understanding about teaching and learning.” Drawing on Barad’s ideas of performativity to challenge our habitual anthropocentric analytical gaze when looking at educational visual data, and using narrative construction, we also aim to give meaning to actions, relations, and experiences of the participants in the YouTube clips. To do this, we present juxtaposing narratives from teachers and students in terms of three “didactic irritations”: (a stories from a track, (b, stories from a game, and (c, stories from a bench. The stories re-present events-of-moving in the data offering insights into embodied experiences in PE practice, making students’ as well as teachers’ actions in PE practice understandable.

  9. Torsional Stability of Aluminum Alloy Seamless Tubing

    Science.gov (United States)

    Moore, R L; Paul, D A

    1939-01-01

    Torsion tests were made on 51ST aluminum-alloy seamless tubes having diameter-to-thickness ratios of from 77 to 139 and length-to-diameter ratios of from 1 to 60. The torsional strengths developed in the tubes which failed elastically (all tubes having lengths greater than 2 to 6 times the diameter) were in most cases within 10 percent of the value indicated by the theories of Donnel, Timoshenko, and Sturm, assuming a condition of simply supported ends.

  10. Literature search for ceramic vacuum tubes

    Energy Technology Data Exchange (ETDEWEB)

    Cannon, W.

    1977-01-12

    The NTIS and Engineering Index files were searched for citations relating to Ceramic and/or Metal Electron Tubes and High Temperature Electronics. A total of 24 citations were found relating directly to ceramic tubes and 24 to high temperature electronics. A search for electron tubes in general was examined for high temperature applications and 39 were obtained. Computer printouts of the abstracts are included in appendices. (MHR)

  11. Ballooning of CANDU pressure tubes - experiments with degraded tube material

    International Nuclear Information System (INIS)

    Three as-received Zr-2.5% Nb pressure tube specimens and three specimens with eight 0.5 mm deep defects machined on the inside surface were tested in the ballooning test rig at Stern Laboratories Inc. The temperature ramp rate was controlled between 28 K s-1 and 35 K s-1. Temperatures on the outside and inside surfaces of the specimens, and circumferential and longitudinal strains were recorded during the transients. Post-test longitudinal, circumferential and wall thickness strains were measured. All as-received specimens ruptured full-length near the top, i.e., the hottest point. All defected specimens failed at either or both upper defects, one rupture being full-length and the others limited to one to three times the length of the defect. (author). 4 refs., 2 tabs., 15 figs

  12. GEIGER-MULLER TYPE COUNTER TUBE

    Science.gov (United States)

    Fowler, I.L.; Watt, L.A.K.

    1959-12-15

    A single counter tube capable of responding to a wide range of intensities is described. The counter tube comprises a tubular cathode and an anode extending centrally of the cathode. The spacing between the outer surface of the anode and the inner surface of the cathode is varied along the length of the tube to provide different counting volumes in adjacent portions of the tube. A large counting volume in one portion adjacent to a low-energy absorption window gives adequate sensitivity for measuring lowintensity radiation, while a smaller volume with close electrode spacing is provided in the counter to make possible measurement of intense garnma radiation fields.

  13. Reducing gain shifts in photomultiplier tubes

    Science.gov (United States)

    Cohn, Charles E.

    1976-01-01

    A means is provided for reducing gain shifts in multiplier tubes due to varying event count rates. It includes means for limiting the number of cascaded, active dynodes of the multiplier tube to a predetermined number with the last of predetermined number of dynodes being the output terminal of the tube. This output is applied to an amplifier to make up for the gain sacrificed by not totally utilizing all available active stages of the tube. Further reduction is obtained by illuminating the predetermined number of dynodes with a light source of such intensity that noise appearing at the output dynode associated with the illumination is negligible.

  14. Small bowel perforation during suprapubic tube exchange.

    Science.gov (United States)

    Mongiu, Anne K; Helfand, Brain T; Kielb, Stephanie J

    2009-02-01

    Suprapubic tube placement is a common urological procedure with a low incidence of complications, including hematuria, catheter blockage, recurrent urinary tract infections, and rarely, injury to adjacent organs. Fortunately, most serious complications are discovered shortly after initial suprapubic tube placement and are readily corrected. Very few cases of delayed complications or injuries have been reported. We report a case of Foley perforation into the ileum during suprapubic tube exchange discovered more than 8 months after initial placement, and preceding numerous monthly changes that occurred without incident. While a rare complication, physicians should be conscious of the potential for delayed injury in patients managed with long term suprapubic tube placement. PMID:19222896

  15. Micro tube heat exchangers for Space Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Mezzo fabricates micro tube heat exchangers for a variety of applications, including aerospace, automotive racing, Department of Defense ground vehicles,...

  16. Modeling Pulse Tube Cryocoolers with CFD

    Science.gov (United States)

    Flake, Barrett; Razani, Arsalan

    2004-06-01

    A commercial computational fluid dynamics (CFD) software package is used to model the oscillating flow inside a pulse tube cryocooler. Capabilities for modeling pulse tubes are demonstrated with preliminary case studies and the results presented. The 2D axi-symmetric simulations demonstrate the time varying temperature and velocity fields in the tube along with computation of the heat fluxes at the hot and cold heat exchangers. The only externally imposed boundary conditions are a cyclically moving piston wall at one end of the tube and constant temperature or heat flux boundaries at the external walls of the hot and cold heat exchangers.

  17. The nasogastric tube syndrome in infants.

    Science.gov (United States)

    Harmon, Jeffrey; Balakrishnan, Karthik; de Alarcon, Alessandro; Hart, Catherine K

    2014-05-01

    This series of three patients is the first description of the presentation, clinical course, and endoscopic findings of nasogastric tube-related airway distress, or nasogastric tube syndrome, in infants. We identify key differences in disease features from those described in adults, based on our literature review. Specifically, infant nasogastric tube syndrome presented as significant respiratory distress and postcricoid inflammation without vocal fold immobility. Symptoms resolved more quickly (mean±SD, 2±1 days) than reported in adults. We suggest that nasogastric tube syndrome should be considered in infants with otherwise unexplained respiratory distress, even in the absence of impaired vocal fold mobility.

  18. RF Breakdown in Drift Tube Linacs

    CERN Document Server

    Stovall, J; Lown, R

    2009-01-01

    The highest RF electric field in drift-tube linacs (DTLs) often occurs on the face of the first drift tube. Typically this drift tube contains a quadrupole focusing magnet whose fringing fields penetrate the face of the drift tube parallel to the RF electric fields in the accelerating gap. It has been shown that the threshold for RF breakdown in RF cavities may be reduced in the presence of a static magnetic field. This note offers a “rule of thumb” for picking the maximum “safe” surface electric field in DTLs based on these measurements.

  19. Are output measurements always necessary after CT tube replacement?

    Directory of Open Access Journals (Sweden)

    Paul J Stauduhar

    2014-03-01

    as: P Stauduhar, A Jones. Are output measurements always necessary after CT tube replacement? Int J Cancer Ther Oncol 2014; 2(2:020238. DOI: 10.14319/ijcto.0202.38

  20. Cancer Statistics: Endometrial Cancer

    Science.gov (United States)

    ... a third party. HPF: Did You Know? Endometrial Cancer Endometrial Cancer - Did you know that endometrial cancer ... mfhs0vbvWi8?rel=0 SEER Stat Fact Sheets: Endometrial Cancer Expand All Collapse All Lifetime risk estimates are ...

  1. Application of enteral nutritional support by needle catheter jejunostomy feeding tube during postoperative adjuvant chemotherapy of staged gastric cancer%延期留置空肠造口管间断肠内营养在进展期胃癌术后辅助化疗中的应用评价

    Institute of Scientific and Technical Information of China (English)

    苏国森; 湛建伟

    2010-01-01

    Objegtive To study the feasibility and clinical effects of enteral nutrition by needle catheter jejunostomy(NCJ)tube in the postoperative adjuvant chemotherapy for patients of staged gastric cancer.Methods Eighty-two patients with staged gastric cancer underwent radical gastrectomy and going to receive chemotherapy were randomly divided into group A(41 cases)and group B(41 cases).All of the patients had been NCJ.Group A received enteral nutrition through the tube during chemotherapy,and group B had been given general diet.A series of parameters were measured post-chemotherapy.And the gastrointestinal complications were carefully observed.Results In post-chemotherapy,the level of hemoglobin,albumin,prealbumin,interleukin-2,natural killer cell activities and CD3+,CDd4+,CD4/CD8 in group A[(106.9±12.0)g/L,(26.2±1.4)g/L,(202.9±32.2)mg/L,(11.9±2.1)μg/L,(21.3±5.2)%,(62.9±3.3)%,(26.1±4.7)%,1.1±0.2]were significantly higher than those in group B(P<0.05 or<0.01).The incidences of vomiting in group A(4.9%,2/41)was significantly lower than that in group B (26.8%,11/41)(P<0.05).The average intake in group A[(1312±114)ml]was significantly more than that in group B[(76.5±186)ml](P<0.05).No severe enteral nutrition related complications occurred in group A.Conclusions It is safe and feasible to enteral nutrition supported by NCJ tube in chemotherapy for patients of staged gastric cancer.It can improve the nutrition status and immune function in the given patients.%目的 研究延期留置空肠造口管间断肠内营养在进展期胃癌术后辅助化疗中应用的可行性及疗效.方法 将进展期胃癌术后行辅助化疗的82例患者按机械抽样法随机分成A、B两组,每组各41例.均于术中放置空肠造口管,A组延期留置空肠造口管至化疗6个疗程结束,每个化疗疗程经空肠造口管给予肠内营养液;B组于化疗前拔除空肠造口管,每个化疗疗程给予普通饮食.比较化疗后两组营养及免疫指

  2. Repair of diaphragmatic injury and placement of tube thoracostomy during right upper quadrant peritonectomy

    Science.gov (United States)

    Ozgul, Nejat; Basaran, Derman; Salman, M. Coskun

    2016-01-01

    Objective Patients with advanced or recurrent ovarian cancer often have metastatic disease in the upper abdominal region, especially to the right hemidiaphragm, which requires diaphragmatic resection in order to achieve optimal cytoreduction. The aim of this surgical video is to demonstrate repair of a diaphragmatic injury and placement of tube thoracostomy during right upper quadrant peritonectomy in a patient with recurrent ovarian cancer. Methods This is the case of a 45-year-old woman presented with platinum sensitive recurrent ovarian cancer. Abdomen computed tomography also confirmed peritoneal carcinomatosis and pelvic recurrent mass. HIPEC was administered after complete cytoreduction including bilateral upper quadrant peritonectomy, during which diaphragmatic injury occurred near the central tendon and pleural cavity was entered. We inserted a chest tube through the 6th intercostal space in the anterior axillary line in order to prevent postoperative massive pleural effusion. Diaphragmatic defect was closed primarily after the tube placement. The chest tube was withdrawn on the third postoperative day and the patient was discharged on postoperative day 25 without any complications. Results The central tendon of diaphragm is the most vulnerable part for lacerations. Diaphragmatic repairs could be performed by various techniques; interrupted or continuous, locking or non-locking sutures, with either permanent or absorbable materials. In our view, all of the techniques provide similar results and surgeons can choose any of them as long as they are comfortable with the procedure. Conclusion In most cases, these lacerations can be repaired primarily without necessitating tube thoracostomy. However, performance of HIPEC can cause massive pleural effusions which can lead to significant pulmonary morbidity. Therefore, retrograde placement of the chest tube under direct vision is quite straightforward when the diaphragm is opened. PMID:26463433

  3. Failure Analysis of Retired Steam Generator Tubings

    International Nuclear Information System (INIS)

    Since the first commercial operation of Kori-1 in 1978, 20 units of nuclear power plants are operated, and the it covers 40 % of total electricity in Korea as of 2008. A steam generator tube rupture incident occurred in the Ulchin unit 4 in 2002, which made the public sensitive to nuclear power plant. In order to keep the nuclear energy as a main energy source, the integrity of steam generator should be demonstrated. It is important to improve a flaw detection capability of the eddy current testing(ECT) in steam generator(SG) tubings in order to maintain the tube integrity. A quantified evaluation on the flaws on SG tubings, which is crucial for the tube integrity evaluation is not satisfactory. It is necessary to utilize the retired SG having various types of corrosion damages. In addition, an examination of pulled tube from Kori 1 retired steam generator will give us information about effectiveness of a remedial action(TiO2 addition) which was applied to mitigate ODSCC. A crack growth model is also needed to ensure a tube repair criteria for a next fuel cycle based on the ASME safety evaluation code, which has to meet a requirement that the flaws have to sustain under three times of normal operation pressure difference and 1.4 times of severe accident condition. In this project, hardware such as semi hot lab for pulled tube examination and modification of transportation cask for pulled tube and software such as procedure of transportation of radioactive steam generator tube and non-destructive and destructive examination of pulled tube were established. The non-destructive and destructive examination of pulled tubes from Kori 1 retired steam generator were performed in the semi hot lab. An effect of remedial actions applied to Kori 1 retired steam generator, PWSCC trend and bulk water chemistry and crevice chemistry in Kori 1 were evaluated. An electrochemical decontamination technology for pulled tube was developed to reduce a radiation exposure and enhance

  4. Reference factor F(CT)Q and X ray tube ionization yield R(TUBE)Q

    International Nuclear Information System (INIS)

    The operational facility procedures in diagnostic radiology standardization and calibration, through the relation between the X ray tube current and the ionization chamber current in a radiation quality Q, shown the reference factor F(CT)Q as the reality estimate to the X ray tube ionization yield, R(TUBE)Q . (author)

  5. A secure method of nasal endotracheal tube stabilization with suture and rubber tube.

    Science.gov (United States)

    Ota, Y; Karakida, K; Aoki, T; Yamazaki, H; Arai, I; Mori, Y; Nakatogawa, N; Suzuki, T

    2001-12-01

    A new method of stabilizing the nasal endotrascheal tube was described. The tube was secured to the anterior portion of the nasal septum with braided silk thread, which was tightened over the rubber tube to keep air route of the cuff open. There found no complications such as unplanned extubation, necrosis and infections of the nasal septum.

  6. Failure analysis of retired steam generator tubings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hong Pyo; Kim, J. S.; Hwang, S. S. and others

    2005-04-15

    Degradation of steam generator leads to forced outage and extension of outage, which causes increase in repair cost, cost of purchasing replacement power and radiation exposure of workers. Steam generator tube rupture incident occurred in Uljin 4 in 2002, which made public sensitive to nuclear power plant. To keep nuclear energy as a main energy source, integrity of steam generator should be demonstrated. Quantitative relationship between ECT(eddy current test) signal and crack size is needed in assesment of integrity of steam generator in pressurized water reactor. However, it is not fully established for application in industry. Retired steam generator of Kori 1 has many kinds of crack such as circumferential and axial primary water stress corrosion crack and outer diameter stress corrosion crack(ODSCC). So, it can be used in qualifying and improving ECT technology and in condition monitoring assesment for crack detected in ISI(in service inspection). In addition, examination of pulled tube of Kori 1 retired steam generator will give information about effectiveness of non welded sleeving technology which was employed to repair defect tubes and remedial action which was applied to mitigate ODSCC. In this project, hardware such as semi hot lab. for pulled tube examination and modification transportation cask for pulled tube and software such as procedure of transportation of radioactive steam generator tube and non-destructive and destructive examination of pulled tube were established. Non-destructive and destructive examination of pulled tubes from Kori 1 retired steam generator were performed in semi hot lab. Remedial actions applied to Kori 1 retired steam generator, PWSCC trend and bulk water chemistry and crevice chemistry in Kori 1 were evaluated. Electrochemical decontamination technology for pulled tube was developed to reduce radiation exposure and enhance effectiveness of pulled tube examination. Multiparameter algorithm developed at ANL, USA was

  7. Cancer - resources

    Science.gov (United States)

    Resources - cancer ... The following organizations are good resources for information on cancer : American Cancer Society -- www.cancer.org Cancer Care -- www.cancercare.org National Cancer Institute -- www.cancer.gov

  8. Cancer Statistics

    Science.gov (United States)

    ... What Is Cancer? Cancer Statistics Cancer Disparities Cancer Statistics Cancer has a major impact on society in ... success of efforts to control and manage cancer. Statistics at a Glance: The Burden of Cancer in ...

  9. Cerebral air embolism as a complication of peptic ulcer in the gastric tube: case report

    Directory of Open Access Journals (Sweden)

    Suzuki Takahisa

    2011-12-01

    Full Text Available Abstract Background The reported incidence of ulcer formation in the gastric tube in esophageal replacement is rare. Case Presentation This is the first report of a case of cerebral air embolism as a result of spontaneous perforation of an ulcer in the constructed gastric tube into the pulmonary vein during post-operative follow-up in a patient with esophageal cancer. Conclusions Cerebral air embolism is a rare complication of penetrating gastric ulcer, but should be considered in patients with a history of esophagectomy with gastric conduit that present with acute neurologic findings.

  10. Working session 2: Tubing inspection

    Energy Technology Data Exchange (ETDEWEB)

    Guerra, J. [Tecnatom, S.A. San Sebastian de los Reyes, Madrid (Spain); Tapping, R.L. [AECL, Chalk River, Ontario (Canada)

    1997-02-01

    This session was attended by delegates from 10 countries, and four papers were presented. A wide range of issues was tabled for discussion. Realizing that there was limited time available for more detailed discussion, three topics were chosen for the more detailed discussion: circumferential cracking, performance demonstration (to focus on POD and sizing), and limits of methods. Two other subsessions were organized: one dealt with some challenges related to the robustness of current inspection methods, especially with respect to leaving cracked tubes in service, and the other with developing a chart of current NDE technology with recommendations for future development. These three areas are summarized in turn, along with conclusions and/or recommendations. During the discussions there were four presentations. There were two (Canada, Japan) on eddy current probe developments, both of which addressed multiarray probes that would detect a range of flaws, one (Spain) on circumferential crack detection, and one (JRC, Petten) on the recent PISC III results.

  11. Pressure tube life management in CANDU-6 nuclear plant

    International Nuclear Information System (INIS)

    Operating parameters of pressure tube in CANDU-6 reactor, the relation between pressure tube life and plant life improvement of pressure tube by AECL in past years were summarized, and the factors affecting pressure tube life, idea and main measures of pressure tube life management in QINSHAN CANDU-6 power plant introduced

  12. Microphone Detects Boiler-Tube Leaks

    Science.gov (United States)

    Parthasarathy, S. P.

    1985-01-01

    Unit simple, sensitive, rugged, and reliable. Diaphragmless microphone detects leaks from small boiler tubes. Porous plug retains carbon granules in tube while allowing pressure changes to penetrate to granules. Has greater life expectancy than previous controllers and used in variety of hot corrosive atmospheres.

  13. Sampling Artifacts from Conductive Silicone Tubing

    Energy Technology Data Exchange (ETDEWEB)

    Timko, Michael T.; Yu, Zhenhong; Kroll, Jesse; Jayne, John T.; Worsnop, Douglas R.; Miake-Lye, Richard C.; Onasch, Timothy B.; Liscinsky, David; Kirchstetter, Thomas W.; Destaillats, Hugo; Holder, Amara L.; Smith, Jared D.; Wilson, Kevin R.

    2009-05-15

    We report evidence that carbon impregnated conductive silicone tubing used in aerosol sampling systems can introduce two types of experimental artifacts: 1) silicon tubing dynamically absorbs carbon dioxide gas, requiring greater than 5 minutes to reach equilibrium and 2) silicone tubing emits organic contaminants containing siloxane that adsorb onto particles traveling through it and onto downstream quartz fiber filters. The consequence can be substantial for engine exhaust measurements as both artifacts directly impact calculations of particulate mass-based emission indices. The emission of contaminants from the silicone tubing can result in overestimation of organic particle mass concentrations based on real-time aerosol mass spectrometry and the off-line thermal analysis of quartz filters. The adsorption of siloxane contaminants can affect the surface properties of aerosol particles; we observed a marked reduction in the water-affinity of soot particles passed through conductive silicone tubing. These combined observations suggest that the silicone tubing artifacts may have wide consequence for the aerosol community and should, therefore, be used with caution. Gentle heating, physical and chemical properties of the particle carriers, exposure to solvents, and tubing age may influence siloxane uptake. The amount of contamination is expected to increase as the tubing surface area increases and as the particle surface area increases. The effect is observed at ambient temperature and enhanced by mild heating (<100 oC). Further evaluation is warranted.

  14. Photomultiplier tubes for Low Level Cerenkov Detectors

    Energy Technology Data Exchange (ETDEWEB)

    Strindehag, O.

    1965-03-15

    Tube backgrounds of several 2-inch photomultiplier types having S11, 'S' , S13 and S20 cathodes are compared by measuring signal and background pulse height distributions at pulse heights corresponding to a few photo-electrons. The reference signal is generated by means of a {beta}-source and a plexiglass radiator. It is found that comparatively good results are obtained with selected tubes of the EMI types 6097B and 9514B having equivalent dark current dc values down to 10{sup -12} input lumens. Special interest is devoted to the correlation between the measured tube backgrounds and the dark current dc values of the tubes, as a good correlation between these parameters simplifies the selection of photomultiplier tubes. The equivalent dark currents of the tested tubes extend over the range 10{sup -12} to 10{sup -9} input lumens. Although the investigation deals with photomultiplier tubes intended for use in low level Cerenkov detectors it is believed that the results could be valuable in other fields where photomultiplier tubes are utilized for the detection of weak light pulses.

  15. Quality assessment of aluminized steel tubes

    OpenAIRE

    K. Żaba

    2010-01-01

    The results of assessments of the welded steel tubes with the Al-Si coating intended for the motorization needs – are presented in thepaper. The measurement of mechanical properties, tube diameters and thickness, internal flash heights as well as the alternative assessmentof the weld quality were performed. The obtained results are presented by means of tools available in the Statistica program andmacroscopic observations.

  16. Shrinking plastic tubing and nonstandard diameters

    Science.gov (United States)

    Ruiz, W. V.; Thatcher, C. S.

    1980-01-01

    Process allows larger-than-normal postshrink diameters without splitting. Tetrafluoroethylene tubing on mandrel is supported within hot steel pipe by several small diameter coil sections. Rising temperature of mandrel is measured via thermocouple so assembly can be removed without overshrinking (and splitting) of tubing.

  17. Confined Tube Crimp Using Portable Hand Tools

    Energy Technology Data Exchange (ETDEWEB)

    Reynolds, Joseph James [Los Alamos National Laboratory; Pereyra, R. A. [LANL Retired; Archuleta, Jeffrey Christopher [Los Alamos National Laboratory; Martinez, Isaac P. [Los Alamos National Laboratory; Nelson, A. M. [MST-16 Summer Student (2007); Allen, Ronald Scott [Los Alamos National Laboratory; Page, R. L. [LANL Retired; Freer, Jerry Eugene [Los Alamos National Laboratory; Dozhier, Nathan Gus [Los Alamos National Laboratory

    2016-04-04

    The Lawrence Radiation Laboratory developed handheld tools that crimp a 1/16 inch OD tube, forming a leak tight seal1 (see Figure 1). The leak tight seal forms by confining the 1/16 inch OD tubing inside a die while applying crimp pressure. Under confined pressure, the tube walls weld at the crimp. The purpose of this study was to determine conditions for fabricating a leak tight tube weld. The equipment was used on a trial-and-error basis, changing the conditions after each attempt until successful welds were fabricated. To better confine the tube, the die faces were polished. Polishing removed a few thousandths of an inch from the die face, resulting in a tighter grip on the tubing wall. Using detergent in an ultrasonic bath, the tubing was cleaned. Also, the time under crimp pressure was increased to 30 seconds. With these modifications, acceptable cold welds were fabricated. After setting the conditions for an acceptable cold weld, the tube was TIG welded across the crimped face.

  18. Development of Zirconium alloys (for pressure tubes)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Suk; Kwon, Sang Chul; Choo, Ki Nam; Jung, Chung Hwan; Yim, Kyong Soo; Kim, Sung Soo; Baek, Jong Hyuk; Jeong, Yong Hwan; Kim, Kyong Ho; Cho, Hae Dong [Korea Atomic Energy Research Inst., Daeduk (Korea, Republic of); Hwang, S. K.; Kim, M. H. [Inha Univ., Incheon (Korea, Republic of); Kwon, S. I [Korea Univ., Seoul (Korea, Republic of); Kim, I. S. [Korea Advanced Inst. of Science and Technology, Taejon (Korea, Republic of)

    1997-09-01

    The objective of this research is to set up the basic technologies for the evaluation of pressure tube integrity and to develop improved zirconium alloys to prevent pressure tube failures due to DHC and hydride blister caused by excessive creep-down of pressure tubes. The experimental procedure and facilities for characterization of pressure tubes were developed. The basic research related to a better understanding of the in-reactor performances of pressure tubes leads to noticeable findings for the first time : the microstructural effect on corrosion and hydrogen pick-up behavior of Zr-2.5Nb pressure tubes, texture effect on strength and DHC resistance and enhanced recrystallization by Fe in zirconium alloys and etc. Analytical methodology for the assessment of pressure tubes with surface flaws was set up. A joint research is being under way with AECL to determine the fracture toughness of O-8 at the EOL (End of Life) that had been quadruple melted and was taken out of the Wolsung Unit-1 after 10 year operation. In addition, pressure tube with texture controlled is being made along with VNINM in Russia as a joint project between KAERI and Russia. Finally, we succeeded in developing 4 different kinds of zirconium alloys with better corrosion resistance, low hydrogen pickup fraction and higher creep strength. (author). 121 refs., 65 tabs., 260 figs

  19. Distortion Of Pressure Signals In Pneumatic Tubes

    Science.gov (United States)

    Whitmore, Stephen A.; Gilyard, Glenn B.; Curry, Robert; Lindsey, William

    1993-01-01

    NASA technical memorandum describes experimental investigation of distorting effects of propagation of pressure signals along narrow pneumatic tubes from pressure-sensing orifices on surfaces of models or aircraft to pressure sensors distant from orifices. Pressure signals distorted principally by frictional damping along walls of tubes and by reflections at orifice and sensor ends.

  20. Ultrasonic Inspection Of Welds On Tube Fittings

    Science.gov (United States)

    Ray, Arjun N.; Nummelin, John L.

    1996-01-01

    Scanning ultrasonic apparatus designed for use in nondestructive inspection of electron-beam welds between heat-exchanger tube and end fittings. Includes ultrasonic probe, scanning mechanism, ultrasonic-signal-generating and -processing circuits, and computers. Not necessary to immerse any part of apparatus or tube/fitting assembly in water during inspection. Output ultrasonic-test signals displayed on computer to reveal defects.

  1. Broadcast yourself on YouTube - really?

    NARCIS (Netherlands)

    G. Kruitbosch; F. Nack

    2008-01-01

    One essential reason for people to publish on the web is to express themselves freely. YouTube facilitates this self-expression by allowing users to upload video content they generated. This paper investigates to what extent the videos on YouTube are self-generated content, instead of amalgamated co

  2. Places to Go: YouTube

    Science.gov (United States)

    Downes, Stephen

    2008-01-01

    Founded in 2005 by three former PayPal employees, YouTube has revolutionized the Internet, marking a change from the static Internet to the dynamic Internet. In this edition of Places to Go, Stephen Downes discusses how the rise of a ubiquitous media format--Flash video--has made YouTube's success possible and argues that Flash video has important…

  3. Teaching Shakespeare with YouTube

    Science.gov (United States)

    Desmet, Christy

    2009-01-01

    YouTube, the video sharing website that allows viewers to upload video content ranging from cute dog tricks to rare rock videos, also supports a lively community devoted to the performance of Shakespeare and Shakespearean adaptations. YouTube is also a popular site for student producers of Shakespeare performances, parodies, and other artistic…

  4. Fibreoptic Bronchoscope for Nasogastric Tube Placement

    Directory of Open Access Journals (Sweden)

    Bhandari Dhiraj

    2015-09-01

    Full Text Available A patient of stage III squamous cell carcinoma of mandible with hemi-mandibulectomy, modified radical neck dissection and radiotherapy required Ryle’s Tube (RT insertion for feeding. This case report describes use of fibreoptic bronchoscope to place an endotracheal tube in oesophagus through nasal route which was then used as a conduit to pass a RT into stomach.

  5. Swelling of spent fuel storage tubes

    International Nuclear Information System (INIS)

    Unexpected swelling phenomena have been reported in the storage racks of the spent fuel pool at several nuclear power plants. Experimental and analytical studies have been carried out in order to identify the governing mechanism and to analyze the interaction of the storage tube and the spent fuel element housed in the tube. (author). 2 refs., 7 figs

  6. Coated tube for immunochemical and enzymatic assays

    International Nuclear Information System (INIS)

    Containers such as test tubes suitable for use in solid phase immunochemical, enzymatical and particularly radioimmunoassay procedures are described. The lower part of the tube is a polymer, coated with an inert protein to which a biologically active substance eg an antibody to triiodothyronine, thyroxine or digoxin, is attached. (U.K.)

  7. Sound absorption and reflection with coupled tubes

    NARCIS (Netherlands)

    Eerden, van der Frits

    2000-01-01

    This paper describes a special sound absorbing technique with an accompanying efficient numerical design tool. As a basis pressure waves in a single narrow tube or pore are considered. In such a tube the viscosity and the thermal conductivity of the air, or any other fluid, can have a significant ef

  8. A Flue Gas Tube for Thermoelectric Generator

    DEFF Research Database (Denmark)

    2013-01-01

    The invention relates to a flue gas tube (FGT) (1) for generation of thermoelectric power having thermoelectric elements (8) that are integrated in the tube. The FTG may be used in combined heat and power (CHP) system (13) to produce directly electricity from waste heat from, e.g. a biomass boiler...

  9. Tube formula, Berezinians, and Dwork formula

    CERN Document Server

    Khudaverdian, Hovhannes M

    2007-01-01

    We consider an example of tubes of hypersurfaces in Euclidean space and generalise the tube formula to supercase. By this we assign to a point of the hypersurface in superspace a rational characteristic function. Does this rational function appear when we calculate the zeta-function of an arithmetic variety?

  10. 6 Common Cancers - Prostate Cancer

    Science.gov (United States)

    ... PSA tests. Read More "6 Common Cancers" Articles Lung Cancer / Breast Cancer / Prostate Cancer / Colorectal Cancer / Skin Cancer / Gynecologic Cancers Spring 2007 Issue: Volume 2 Number 2 Page 10 MedlinePlus | Subscribe | Magazine Information | Contact Us | Viewers & ...

  11. 6 Common Cancers - Colorectal Cancer

    Science.gov (United States)

    ... certain people. Read More "6 Common Cancers" Articles Lung Cancer / Breast Cancer / Prostate Cancer / Colorectal Cancer / Skin Cancer / Gynecologic Cancers Spring 2007 Issue: Volume 2 Number 2 Page 11 MedlinePlus | Subscribe | Magazine Information | Contact Us | Viewers & ...

  12. Development of CRD stub tube welding system

    International Nuclear Information System (INIS)

    The reactor pressure vessel (RPV) of nuclear power plants include control rod drive (CRD) stub tubes installed on the inner surface of the bottom head by welding. Weld seams are located at the root of each stub tube, to which accessibility is limited. The weld travel requires an elliptical movement with inclination along the inner bottom head surface, and furthermore the location on the bottom head of each stub tube has different angle of inclination. CRD stub tubes were installed by skilled welders using MIG welding in previous RPV construction. Recently, a CRD stub tube TIG welding system was developed for RPV construction in the near future, which can be applied to such 3 dimensional welding orbit. (author)

  13. Fuel cladding tubes and fuel elements

    International Nuclear Information System (INIS)

    Purpose: To enable non-destructive measurement for the thickness of zirconium barriers. Constitution: Regions capable of non-destructive inspection are provided at the boundary between a fuel cladding tube made of zirconium alloy and the zirconium barrier lined to the inner circumference surface of the tube. As the regions being capable of distinguishing by ultrasonic wave reflection, solid materials, for example, non-metal materials different from that for the tube and the barrier are placed or gaps are provided at the boundary between the zirconium alloy cladding tube and the zirconium barrier. Since ultrasonic waves are reflected at each of the boundaries by the presence of these regions, thickness of the zirconium barrier can be measured in a non-destructive manner from either the inner or the outer surface of the tube. (Yoshino, Y.)

  14. The Mashups of YouTube

    DEFF Research Database (Denmark)

    Simonsen, Thomas Mosebo

    2013-01-01

    This article focuses on YouTube mashups and how we can understand them as a specific subgenre on YouTube. The Mashups are analysed as audiovisual recontextualizations that are given new meaning, e.g., via collaborative social communities or for individual promotional purposes. This is elaborated......, but rather in its social and communicative abilities within the YouTube community. This leads to the article’s overall argument that the main characteristic of the YouTube Mashup can be explained in terms of connectivity. It is argued that Mashups reveal a double articulation of connectivity; one...... that involves the social mechanisms of the Mashups, and another mode, which concerns the explicit embedding of structural connectivity that accentuates the medium-specific infrastructure of YouTube. This double articulation of connectivity is furthermore elaborated on by including Grusin and Bolter’s concept...

  15. Pressure tube rupture in a closed tank

    International Nuclear Information System (INIS)

    A study has been prepared on the feasibility of conducting pressure tube/calandria tube rupture tests in a closed tank, simulating a scaled-down calandria vessel. The study includes: i) a review of previous work, ii) an analytical investigation of the scaling problem of the calandria vessel and relevant in-core structures, iii) selection of a method for initiating pressure tube/calandria tube rupture, iv) a set of specifications for the test assembly, v) general arrangement drawings, vi) a proposal for a test matrix, vii) a survey and evaluation of existing facilities which could provide the required high pressure, temperature and fluid inventory, and viii) a cost estimate for the detailed design and construction, instrumentation, data acquisition and reduction, testing and reporting. The study concludes that it is both technically and practically feasible to conduct pressure tube rupture tests in a closed tank

  16. Ultra-fast framing camera tube

    Science.gov (United States)

    Kalibjian, Ralph

    1981-01-01

    An electronic framing camera tube features focal plane image dissection and synchronized restoration of the dissected electron line images to form two-dimensional framed images. Ultra-fast framing is performed by first streaking a two-dimensional electron image across a narrow slit, thereby dissecting the two-dimensional electron image into sequential electron line images. The dissected electron line images are then restored into a framed image by a restorer deflector operated synchronously with the dissector deflector. The number of framed images on the tube's viewing screen is equal to the number of dissecting slits in the tube. The distinguishing features of this ultra-fast framing camera tube are the focal plane dissecting slits, and the synchronously-operated restorer deflector which restores the dissected electron line images into a two-dimensional framed image. The framing camera tube can produce image frames having high spatial resolution of optical events in the sub-100 picosecond range.

  17. Characterization of oxides on Bruce A NGS liner tubes and steam generator tubes

    International Nuclear Information System (INIS)

    Oxide deposits on end-fitting liner tubes and steam generator tubes from the Bruce A Nuclear Generating Station (NGS) were characterized in advance of the decontamination of the heat transport system (HTS) of Bruce Unit 2. Oxide loadings, and Co-60 surface activities and specific activities were determined for the oxides on inlet and outlet end-fitting liner tubes from Bruce Unit l, Bruce Unit 2 and Bruce Unit 4. Oxides on the inner surfaces of steam generator tubes from Bruce NGS Units 1 and 2 were also characterized. The consistency in the deposit characteristics on the inlet liner tubes and steam generator tubes from Bruce A, along with the absence of magnetite on the outlet liner tubes has led to the development of a model for iron transport in the HTS of pressurized heavy water reactors (PHWRs). The activity transport/fouling mechanism involves flow-accelerated corrosion of the outlet feeder pipes, followed by deposition of iron in the steam generators, along the inlet feeder pipes, on the inlet end fittings, on the inlet fuel bundles and on the inlet region of the pressure tube. The results of loop experiments using decontamination solutions indicated that the oxide was rapidly removed from inlet liner tubes. However, removal of the Cr-rich oxide from the outlet liner tubes was less efficient, requiring the Alkaline Permangante (AP) oxidizing pre-treatment that is typically used in light water reactors (LWRs). The steam generator tubes were effectively decontaminated

  18. Experimental study on in-tube condensation heat transfer characteristics of helically coiled spiral tubes

    Energy Technology Data Exchange (ETDEWEB)

    Park, J.U. [Sunchon First College, Sunchon (Korea); Kweon, Y.C. [Sun Moon University, Chonan (Korea); Han, K.I. [Pukyong National University, Pusan (Korea)

    2001-12-01

    An experimental study on condensation heat transfer characteristics of helically coiled spiral tubes was performed. The refrigerant is R-113. A refrigerant loop was established to measure the condensation heat transfer coefficients. Experiments were carried out uniform heat flux of 15 kW/m{sup 2}, refrigerant quality of 0.1 {approx} 0.9, curvature ratio of 0.016, 0.025 and 0.045. The curvature of a coil was defined as the ratio of the inside diameter of the tube to the diameter of the bending circle. To compare the condensation heat transfer coefficients of coiled spiral tubes, the previous results on coiled plain tubes and straight plain tubes were used. The results shows that the condensation heat transfer coefficients of coiled spiral tubes largely increase, as increasing Re and quality, compared to those of coiled plain tubes and straight plain tubes. As increasing degree of subcooling, however, the condensation heat transfer coefficients on coiled spiral tubes decrease. It is found that the heat transfer enhancement is more better than coiled plain tubes and straight plain tubes, as increasing curvature ratio. (author). 13 refs., 10 figs., 1 tab.

  19. Ultrasonic measurement of gap between calandria tube and liquid injection shutdown system tube in PHWR

    International Nuclear Information System (INIS)

    Sag of CT or liquid injection shutdown system tubes in pressurized heavy water reactor is known to occur due to irradiation creep and growth during plant operation. When the sag of CT is big enough, the CT tube possibly comes in contact with liquid injection shutdown system tube (LIN) crossing beneath the CT, which subsequently may prevent the safe operation. It is therefore necessary to check the gap between the two tubes in order to confirm no contacts when using a proper measure periodically during the plant life. An ultrasonic gap measuring probe assembly which can be fed through viewing port installed on the calandria was developed and utilized to measure the sags of both tubes in a pressurized heavy water reactor in Korea. It was found that the centerlines of CT and LIN can be precisely detected by ultrasonic wave. The gaps between two tubes were easily obtained from the relative distance of the measured centerline elevations of the tubes. But the measured gap data observed at the viewing port were actually not the data at the crossing point of CT and LIN. To get the actual gap between two tubes, mathematical modeling for the deflection curves of two tubes was used. The sags of CT and LIN tubes were also obtained by comparison of the present centerlines with the initial elevations at the beginning of plant operation. The gaps between two tubes in the unmeasurable regions were calculated based on the measurement data and the channel power distribution

  20. Pickering NGS A: Assessment of calandria tube integrity following a sudden pressure tube failure

    International Nuclear Information System (INIS)

    The issue of calandria tube integrity following a sudden rupture of the pressure tube in Pickering NGS A reactor is addressed. Based on operating experience, only fish-mouth ruptures of the pressure tube are considered to be credible. The calandria tube response to the pressure tube break is delineated into three distinct stages, i.e. the initial transient response during the annulus filling stage, transient overpressurization and the final steady-state loading after bellows failure. The annulus response in the second stage is dominated by a waterhammer type overpressure transient with attenuation of this transient due to plastic straining of the calandria tube. The annulus pressure transients for various breaks and the sensitivity of the results to various parameters are presented. The strength margins of the calandria tube are evaluated to be relatively large. (author). 7 refs., 6 tabs., 6 figs

  1. Sleeving repair of heat exchanger tubes

    International Nuclear Information System (INIS)

    Defective heat exchanger tubes can be repaired using techniques that do not involve the cost and schedule penalties of component replacement. FTI's years of experience repairing steam generator tubes have been successfully applied to heat exchangers. Framatome Technologies heat exchanger sleeves can bridge defective areas of the heat exchanger tubes, sleeves have been designed to repair typical heat exchanger tube defects caused by excessive tube vibration, stress corrosion cracking, pitting or erosion. By installing a sleeve, the majority of the tube's heat transfer and flow capacity is maintained and the need to replace the heat exchanger can be delayed or eliminated. Both performance and reliability are improved. FTI typically installs heat exchanger tube sleeves using either a roll expansion or hydraulic expansion process. While roll expansion of a sleeve can be accomplished very quickly, hydraulic expansion allows sleeves to be installed deep within a tube where a roll expander cannot reach. Benefits of FTI's heat exchanger tube sleeving techniques include: - Sleeves can be positioned any where along the tube length, and for precise positioning of the sleeve eddy current techniques can be employed. - Varying sleeve lengths can be used. - Both the roll and hydraulic expansion processes are rapid and both produce joints that do not require stress relief. - Because of low leak rates and speed of installations, sleeves can be used to preventatively repair likely-to-fail tubes. - Sleeves can be used for tube stiffening and to limit leakage through tube defects. - Because of installation speed, there is minimal impact on outage schedules and budgets. FTI's recently installed heat exchanger sleeving at the Kori-3 Nuclear Power Station in conjunction with Korea Plant Service and Engineering Co., Ltd. The sleeves were installed in the 3A and 3B component cooling water heat exchangers. A total of 859 tubesheet and 68 freespan sleeves were installed in the 3A heat

  2. Friction welding of Zr - 2.5 % Nb alloy tubes

    International Nuclear Information System (INIS)

    Investigation results of friction welding for Zr - 2.5 % Nb alloy tubes (dimension 88 x 4 mm) are given. These tubes are manufactured through thermomechanical processing. Optimal welding conditions are defined. Thermal processes at tubes welding are calculated

  3. General Information about Urethral Cancer

    Science.gov (United States)

    ... The surgeon may use part of the small intestine to make a tube that passes urine through an opening ( stoma ). This is called an ostomy or urostomy . If ... surgeon may also use part of the small intestine to make a new storage pouch ( continent ... the urine through a stoma. Even if the doctor removes all the cancer ...

  4. Treatment Options for Urethral Cancer

    Science.gov (United States)

    ... The surgeon may use part of the small intestine to make a tube that passes urine through an opening ( stoma ). This is called an ostomy or urostomy . If ... surgeon may also use part of the small intestine to make a new storage pouch ( continent ... the urine through a stoma. Even if the doctor removes all the cancer ...

  5. Treatment Option Overview (Urethral Cancer)

    Science.gov (United States)

    ... The surgeon may use part of the small intestine to make a tube that passes urine through an opening ( stoma ). This is called an ostomy or urostomy . If ... surgeon may also use part of the small intestine to make a new storage pouch ( continent ... the urine through a stoma. Even if the doctor removes all the cancer ...

  6. Palliative Therapy for Gallbladder Cancer

    Science.gov (United States)

    ... affect a person’s quality of life, when possible. Biliary stent or biliary catheter If cancer is blocking a duct that ... diagnosed? ”) or, in some cases, during surgery. A stent is a small metal or plastic tube that keeps the duct open ...

  7. Folate and Cancer

    Directory of Open Access Journals (Sweden)

    Luciana Yuki Tomita PhD

    2016-07-01

    Full Text Available Folate plays a central role in DNA synthesis and methylation, which are essential for DNA integrity maintenance and gene expression. Folate deficiency may lead to the incorporation of uracil into DNA and chromosome breaks, increasing the risk of cancer. However, conflicting evidence has been observed depending on the type of epidemiological study, dietary or circulating folate, and the type of cancer. New concern has arisen after a mandatory folic acid (FA fortification program adopted for the prevention of neural tube defects in the United States, which suggested an increase in the incidence of colorectal cancer. In the present article, folate status and cancer are under review, and a discussion of the challenge of assessing folate status through food intake, supplement use, FA fortification programs, circulating folate, and the interaction of diet and the polymorphism of the enzyme involved in folate metabolism will be presented.

  8. Multi-tube fuel nozzle with mixing features

    Science.gov (United States)

    Hughes, Michael John

    2014-04-22

    A system includes a multi-tube fuel nozzle having an inlet plate and a plurality of tubes adjacent the inlet plate. The inlet plate includes a plurality of apertures, and each aperture includes an inlet feature. Each tube of the plurality of tubes is coupled to an aperture of the plurality of apertures. The multi-tube fuel nozzle includes a differential configuration of inlet features among the plurality of tubes.

  9. Vibrations of tube arrays in transversal flow

    Energy Technology Data Exchange (ETDEWEB)

    Gibert, R.J.; Villard, B. (C.E.N. Saclay, Gif-sur-Yvette (France)); Chabrerie, J. (Ste Fives-Cail-Babcok, La Courneuve, (France)); Sagner, V. (Ste Bertin, Plaisir (France))

    1981-01-01

    The vibrations induced in tube arrays by a transversal flow are of great practical interest because of their destructive effects especially on heat exchangers. Though turbulence can significantly excite the tubes by itself, most intense vibrations are still caused by two fluid-elastic phenomena: - The << lock-in >> effect: The basic phenomenon consists of a generation and a synchronization of vortex shedding by a transversal tube motion when its frequency approaches the shedding frequency and when its level is large enough. The so modified vortex shedding generates much more intense vibrations. The lock-in effects is well known for a single cylinder. Less results have been obtained for bundles. - The whirling instability: In a tube row or a bundle, quasi-steady forces are generated by the displacements of the tubes in the flow field. Adjacent tubes are disymmetrically coupled by these forces and instability can appear beyond a critical flow velocity. For the tube rows H.J. Connors has shown that the phenomena are characterized by a coefficient c (which is a function of the pitch).

  10. Ultrasonic examination techniques for steam generator tubing

    International Nuclear Information System (INIS)

    Ultrasonic examination techniques for FBR steam generator tubing have been developed which provide high accuracy and high inspection rates. Typical dimensions of the steam generator tubing are 24.2 mm inner diameter and approximately 80 m length, and all tubes are helically wound. In order to perform flaw detection at high speed, three types of electronic scanning multi-array transducer units for axially and circumferentially oriented flaws in the tube and for tube-wall thinning were incorporated into one probe. With this probe, notched flaws of 0.17 mm depth (5% of the wall thickness) and 3 mm length, and tube-wall thinning of 0.2 mm could be detected in the experiments. A probe transportation system using water flow has also been developed. This system is capable of carrying the probe through the entire length of a helically coiled tube at a rate of 4-16 m/min. Inspection tests using these techniques show that flaws can be successfully detected at an inspection rate of 4 m/min. (author)

  11. Carburization of stainless steel furnace tubes

    International Nuclear Information System (INIS)

    Stainless steel containing molybdenum are usually recommended to resist naphtenic acid corrosion in vacuum heaters. In 1993 the original 5Cr-1/2Mo roof tubes of the furnace in a vacuum unit were replaced by stainless steel 316 Ti to minimize tube replacement and increase heater reliability. Unexpectedly, some of the new tubes failed after only three years of service and just one year after undergoing the last inspection. The damage occurred in the form of deep holes and perforations, starting from the outside tube surface on the fireside. Coke build-up occurred due to severe operating conditions, overheating the tubes on the fireside, above 675 Centigrade. Metallographic and Scanning Electron Microscopy (Sem) examination revealed internal and external carburization of the material due to the presence of coke and combustion ashes, respectively. The increase in the skin metal temperature facilitated the diffusion of carbon from these carbon-rich deposits into the low carbon content material (0.023%). Depletion of chromium at the grain boundaries due to the massive formation of chromium carbides, resulted in a severe intergranular corrosion attack by molten salts rich in vanadium and sulfur produced by asphalt burning. Normal operating practice demands the use of steam for the heater tubes to control coke build-up. This practice had been first reduced and then eliminated, during the past two years prior to the failure, because of economic incentives. This paper describes the root cause analysis conducted to account for these premature tube failures. (Author)

  12. Tube Thoracostomy: Complications and Its Management

    Directory of Open Access Journals (Sweden)

    Emeka B. Kesieme

    2012-01-01

    Full Text Available Background. Tube thoracostomy is widely used throughout the medical, surgical, and critical care specialities. It is generally used to drain pleural collections either as elective or emergency. Complications resulting from tube thoracostomy can occasionally be life threatening. Aim. To present an update on the complications and management of complications of tube thoracostomy. Methods. A review of the publications obtained from Medline search, medical libraries, and Google on tube thoracostomy and its complications was done. Results. Tube thoracostomy is a common surgical procedure which can be performed by either the blunt dissection technique or the trocar technique. Complication rates are increased by the trocar technique. These complications have been broadly classified as either technical or infective. Technical causes include tube malposition, blocked drain, chest drain dislodgement, reexpansion pulmonary edema, subcutaneous emphysema, nerve injuries, cardiac and vascular injuries, oesophageal injuries, residual/postextubation pneumothorax, fistulae, tumor recurrence at insertion site, herniation through the site of thoracostomy, chylothorax, and cardiac dysrhythmias. Infective complications include empyema and surgical site infection. Conclusion. Tube thoracostomy, though commonly performed is not without risk. Blunt dissection technique has lower risk of complications and is hence recommended.

  13. Tube thoracostomy: complications and its management.

    Science.gov (United States)

    Kesieme, Emeka B; Dongo, Andrew; Ezemba, Ndubueze; Irekpita, Eshiobo; Jebbin, Nze; Kesieme, Chinenye

    2012-01-01

    Background. Tube thoracostomy is widely used throughout the medical, surgical, and critical care specialities. It is generally used to drain pleural collections either as elective or emergency. Complications resulting from tube thoracostomy can occasionally be life threatening. Aim. To present an update on the complications and management of complications of tube thoracostomy. Methods. A review of the publications obtained from Medline search, medical libraries, and Google on tube thoracostomy and its complications was done. Results. Tube thoracostomy is a common surgical procedure which can be performed by either the blunt dissection technique or the trocar technique. Complication rates are increased by the trocar technique. These complications have been broadly classified as either technical or infective. Technical causes include tube malposition, blocked drain, chest drain dislodgement, reexpansion pulmonary edema, subcutaneous emphysema, nerve injuries, cardiac and vascular injuries, oesophageal injuries, residual/postextubation pneumothorax, fistulae, tumor recurrence at insertion site, herniation through the site of thoracostomy, chylothorax, and cardiac dysrhythmias. Infective complications include empyema and surgical site infection. Conclusion. Tube thoracostomy, though commonly performed is not without risk. Blunt dissection technique has lower risk of complications and is hence recommended. PMID:22028963

  14. Steam generator tubing NDE performance

    Energy Technology Data Exchange (ETDEWEB)

    Henry, G. [Electric Power Research Institute, Charlotte, NC (United States); Welty, C.S. Jr. [Electric Power Research Institute, Palo Alto, CA (United States)

    1997-02-01

    Steam generator (SG) non-destructive examination (NDE) is a fundamental element in the broader SG in-service inspection (ISI) process, a cornerstone in the management of PWR steam generators. Based on objective performance measures (tube leak forced outages and SG-related capacity factor loss), ISI performance has shown a continually improving trend over the years. Performance of the NDE element is a function of the fundamental capability of the technique, and the ability of the analysis portion of the process in field implementation of the technique. The technology continues to improve in several areas, e.g. system sensitivity, data collection rates, probe/coil design, and data analysis software. With these improvements comes the attendant requirement for qualification of the technique on the damage form(s) to which it will be applied, and for training and qualification of the data analysis element of the ISI process on the field implementation of the technique. The introduction of data transfer via fiber optic line allows for remote data acquisition and analysis, thus improving the efficiency of analysis for a limited pool of data analysts. This paper provides an overview of the current status of SG NDE, and identifies several important issues to be addressed.

  15. Atmosphere in a Test Tube

    Science.gov (United States)

    Claudi, R.; Pace, E.; Ciaravella, A.; Micela, G.; Piccioni, G.; Billi, D.; Cestelli Guidi, M.; Coccola, L.; Erculiani, M. S.; Fedel, M.; Galletta, G.; Giro, E.; La Rocca, N.; Morosinotto, T.; Poletto, L.; Schierano, D.; Stefani, S.

    The ancestor philosophers' dream of thousand of new world is finally realised: more than 1800 extrasolar planets have been discovered in the neighborhood of our Sun. Most of them are very different from those we used to know in our Solar System. Others orbit the Habitable Zone (HZ) of their parent stars. Space missions, as JWST and the very recently proposed ARIEL, or ground based instruments, like SPHERE@VLT, GPI@GEMINI and EPICS@ELT, have been proposed and built to measure the atmospheric transmission, reflection and emission spectra over a wide wavelength range of these new worlds. In order to interpret the spectra coming out by this new instrumentation, it is important to know in detail the optical characteristics of gases in the typical physical conditions of the planetary atmospheres and how those characteristics could be affected by radiation driven photochemical and bio-chemical reaction. Insights in this direction can be achieved from laboratory studies of simulated planetary atmosphere of different pressure and temperature conditions under the effects of radiation sources, used as proxies of different bands of the stellar emission. ''Atmosphere in a Test Tube'' is a collaboration among several Italian astronomical, biological and engineering institutes in order to share their experiencece in performing laboratory experiments on several items concerning extrasolar planet atmospheres.

  16. Steam generator tubing NDE performance

    International Nuclear Information System (INIS)

    Steam generator (SG) non-destructive examination (NDE) is a fundamental element in the broader SG in-service inspection (ISI) process, a cornerstone in the management of PWR steam generators. Based on objective performance measures (tube leak forced outages and SG-related capacity factor loss), ISI performance has shown a continually improving trend over the years. Performance of the NDE element is a function of the fundamental capability of the technique, and the ability of the analysis portion of the process in field implementation of the technique. The technology continues to improve in several areas, e.g. system sensitivity, data collection rates, probe/coil design, and data analysis software. With these improvements comes the attendant requirement for qualification of the technique on the damage form(s) to which it will be applied, and for training and qualification of the data analysis element of the ISI process on the field implementation of the technique. The introduction of data transfer via fiber optic line allows for remote data acquisition and analysis, thus improving the efficiency of analysis for a limited pool of data analysts. This paper provides an overview of the current status of SG NDE, and identifies several important issues to be addressed

  17. Tube Formation in Nanoscale Materials

    Directory of Open Access Journals (Sweden)

    Yan Chenglin

    2008-01-01

    Full Text Available Abstract The formation of tubular nanostructures normally requires layered, anisotropic, or pseudo-layered crystal structures, while inorganic compounds typically do not possess such structures, inorganic nanotubes thus have been a hot topic in the past decade. In this article, we review recent research activities on nanotubes fabrication and focus on three novel synthetic strategies for generating nanotubes from inorganic materials that do not have a layered structure. Specifically, thermal oxidation method based on gas–solid reaction to porous CuO nanotubes has been successfully established, semiconductor ZnS and Nb2O5nanotubes have been prepared by employing sacrificial template strategy based on liquid–solid reaction, and an in situ template method has been developed for the preparation of ZnO taper tubes through a chemical etching reaction. We have described the nanotube formation processes and illustrated the detailed key factors during their growth. The proposed mechanisms are presented for nanotube fabrication and the important pioneering studies are discussed on the rational design and fabrication of functional materials with tubular structures. It is the intention of this contribution to provide a brief account of these research activities.

  18. p53通路微小RNA在卵巢癌细胞和浆液性卵巢癌组织中的表达及意义%Expression and significance of microRNAs in the p53 pathway in ovarian cancer cells and serous ovarian cancer tissues

    Institute of Scientific and Technical Information of China (English)

    张旗; 何湘君; 马丽萍; 李娜; 杨静; 成夜霞; 崔恒

    2011-01-01

    were transfected with pre-microRNAs and the cell-cycle changes were detected.The expression level of miR-449a/b,miR-34a,miR-34b,miR-34c,miR-192 and miR-194 in serous ovarian carcinomas of varying grade and stage were compared with real-time PCR.Results The expressions of miR-449a/b,miR-34b and miR-34c were 19-fold to 21-fold elevated after p53 activation by genotoxic agent. Ectopic expression of miR-449b,as well as miR-34c,resulted in cell-cycle arrest in SKOV3.ipl cells.The expression of miR-449a/b was parallel with that of miR-34b,miR-34c,and were significantly lower in late stage and high-grade serous carcinomas than in the normal fallopian tube,early stage and low-grade serous carcinomas.The expression of miR-192,miR-194 and miR-34a did not show evident features in serous ovarian carcinomas and were much lower than miR-449a/b,miR-34b and miR-34c in normal fallopian tube.Conclusions As tumor-suppressor microRNAs,miR-449a/b,miR-34b and miR-34c cooperate and play important roles in p53 pathway. Their inactivation may contribute to the carcinogenesis and progression of serous ovarian carcinomas.

  19. Influence of furnace tube shapeon thermal strain of fire-tube boilers

    Directory of Open Access Journals (Sweden)

    Gaćeša Branka

    2014-01-01

    Full Text Available The aim of this paper is to use numerical analysis and fine element method-FEM to investigate the influence of furnace tube shape on the thermal strain of fire-tube boilers. Thermal stresses in corrugated furnace tubes of different shape, i.e. with different corrugation pitch and depth, were analysed first. It was demonstrated that the thermal stresses in corrugated furnace tube are significantly reduced with the increase of corrugation depth. Than deformations and stresses in the structure of a fire-tube boiler were analysed in a real operating condition, for the cases of installed plain furnace tube and corrugated furnace tubes with different shapes. It was concluded that in this fire-tube boiler, which is of larger steam capacity, the corrugated furnace tube must be installed, as well as that the maximal stress in the construction is reduced by the installation of the furnace tube with greater corrugation depth. The analysis of stresses due to pressure and thermal loads pointed out that thermal stresses are not lower-order stresses in comparison to stresses due to pressure loads, so they must be taken into consideration for boiler strength analysis. [Projekat Ministarstva nauke Republike Srbije, br. TR 35040 i br. TR 35011

  20. An investigation on SA 213-Tube to SA 387-Tube plate using friction welding process

    International Nuclear Information System (INIS)

    Friction welding of tube to tube plate using an external tool (FWTPET) is a relatively newer solid state welding process used for joining tube to tube plate of either similar or dissimilar materials with enhanced mechanical and metallurgical properties. In the present study, FWTPET has been used to weld SA 213 (Grade T12) tube with SA 387 (Grade 22) tube plate. The welded samples are found to have satisfactory joint strength and the Energy dispersive X-ray analysis (EDX), X-ray diffraction (XRD) study showed that inter metallic compound is absent in the weld zone. The different weld joints have been identified and the phase composition is found using EDX and XRD. Microstructures have been analyzed using optical and Scanning electron microscopy (SEM). The mechanical properties such as hardness, compressive shear strength and peel test for different weld conditions are studied and the hardness survey revealed that there is increase in hardness at the weld interface due to grain refinement. The corrosion behavior for different weld conditions have been analyzed and the weld zone is found to have better corrosion resistance due to the influence of the grain refinement after FWTPET welding process. Hence, the present investigation is carried out to study the behavior of friction welded dissimilar joints of SA 213 tube and SA 387 tube plate joints and the results are presented. The present study confirms that a high quality tube to tube plate joint can be achieved using FWTPET process at 1120 rpm

  1. CATHENA Code Assessment for Pressure Tube and Calandria Tube Contact Phenomena

    International Nuclear Information System (INIS)

    Canadian Algorithm for THErmalhydraulic Network Analysis (CATHENA), has been validated against full-scale Contact Boiling Experiments conducted using specific channel power, pressure, and moderator subcooling as pre-test conditions. The pressure tube (PT) and calandria tube (CT) temperatures, the extent of dryout and failures of the pressure tube or the calandria tube (if any) are the outcome of these experiments. Recently, an IAEA International Collaborative Standard Problem (ICSP) to provide contact boiling experimental data to participants for assessing the subcooling requirements for a heated pressure tube, plastically deforming into contact with the calandria tube during a postulated large break LOCA condition has been performed. The CATHENA code assessment results against the experimental data distributed for the ICSP are provided in this paper. The CATHENA code is used to simulate the experiment on pressure tube ballooning conducted at the AECL. The overall code's predictions show good agreements with the experimental data. The contact timing by the pressure tube ballooning is predicted accurately, however, it is found that the code largely underpredict the peak temperature at the pressure tube and the calandria tube. This discrepancy seems to be induced from multi-dimensional flow effects in the water tank. For more accurate calculations, detailed modeling of the water tank is required

  2. An investigation on SA 213-Tube to SA 387-Tube plate using friction welding process

    Energy Technology Data Exchange (ETDEWEB)

    Rajan, S. Pandia; Kumaraswamidhas, L. A. [Indian Institute of Technology, Jharkhand (India); Kumaran, S. Senthil [RVS School of Engineering and Technology, Tamil Nadu (India); Muthukumaran, S. [National Institute of Technology, Tamil Nadu (India)

    2016-01-15

    Friction welding of tube to tube plate using an external tool (FWTPET) is a relatively newer solid state welding process used for joining tube to tube plate of either similar or dissimilar materials with enhanced mechanical and metallurgical properties. In the present study, FWTPET has been used to weld SA 213 (Grade T12) tube with SA 387 (Grade 22) tube plate. The welded samples are found to have satisfactory joint strength and the Energy dispersive X-ray analysis (EDX), X-ray diffraction (XRD) study showed that inter metallic compound is absent in the weld zone. The different weld joints have been identified and the phase composition is found using EDX and XRD. Microstructures have been analyzed using optical and Scanning electron microscopy (SEM). The mechanical properties such as hardness, compressive shear strength and peel test for different weld conditions are studied and the hardness survey revealed that there is increase in hardness at the weld interface due to grain refinement. The corrosion behavior for different weld conditions have been analyzed and the weld zone is found to have better corrosion resistance due to the influence of the grain refinement after FWTPET welding process. Hence, the present investigation is carried out to study the behavior of friction welded dissimilar joints of SA 213 tube and SA 387 tube plate joints and the results are presented. The present study confirms that a high quality tube to tube plate joint can be achieved using FWTPET process at 1120 rpm.

  3. Gastrostomy Tube Placement Without Nasogastric Tube: A Retrospective Evaluation in 85 Patients

    Energy Technology Data Exchange (ETDEWEB)

    Heberlein, Wolf E., E-mail: weheberlein@uams.edu; Goodwin, Whitney J.; Wood, Clint E.; Yousaf, Muhammad; Culp, William C. [University of Arkansas for Medical Sciences, Department of Radiology (United States)

    2012-12-15

    Purpose: Our study evaluated techniques for percutaneous gastrostomy (G)-tube placement without the use of a nasogastric (NG) tube. Instead, direct puncture of a physiologic air bubble or effervescent-enhanced gastric bubble distention was performed in patients with upper digestive tract obstruction (UDTO) or psychological objections to NG tubes. Materials and Methods: A total of 886 patients underwent G-tube placement in our department during a period of 7 years. We present our series of 85 (9.6%) consecutive patients who underwent percutaneous G-tube placement without use of an NG tube. Results: Of these 85 patients, fluoroscopic guided access was attempted by direct puncture of a physiologically present gastric air bubble in 24 (28%) cases. Puncture of an effervescent-induced large gastric air bubble was performed in 61 (72%) patients. Altogether, 82 (97%) of 85 G tubes were successfully placed in this fashion. The three failures comprised refusal of effervescent, vomiting of effervescent, and one initial tube misplacement when a deviation from our standard technique occurred. Conclusion: The described techniques compare favorably with published large series on G-tube placement with an NG tube in place. The techniques are especially suited for patients with UDTO due to head, neck, or esophageal malignancies, but they should be considered as an alternative in all patients. Direct puncture of effervescent-enhanced gastric bubble distention is a safe, patient-friendly and effective technique.

  4. Scintillation probe with photomultiplier tube saturation indicator

    Science.gov (United States)

    Ruch, Jeffrey F.; Urban, David J.

    1996-01-01

    A photomultiplier tube saturation indicator is formed by supplying a supplemental light source, typically an light emitting diode (LED), adjacent to the photomultiplier tube. A switch allows the light source to be activated. The light is forwarded to the photomultiplier tube by an optical fiber. If the probe is properly light tight, then a meter attached to the indicator will register the light from the LED. If the probe is no longer light tight, and the saturation indicator is saturated, no signal will be registered when the LED is activated.

  5. Product presentations on YouTube

    OpenAIRE

    Přibyl, Tomáš

    2014-01-01

    The main aim of this thesis is to characterize properties of the portal YouTube, with a focus on opportunities for promotion, evaluate and analyze the use of the portal YouTube - part of the marketing strategy of chosen company. Based of findings arising from the analysis of the research, is applied marketing concept of promotion the selected company. Furthermore the cost of creating and operating the concept is investigated and subsequently the potential benefits of using YouTube in marketin...

  6. YouTube and ‘psychiatry’

    OpenAIRE

    Gordon, Robert; Miller, John; Collins, Noel

    2015-01-01

    YouTube is a video-sharing website that is increasingly used to share and disseminate health-related information, particularly among younger people. There are reports that social media sites, such as YouTube, are being used to communicate an anti-psychiatry message but this has never been confirmed in any published analysis of YouTube clip content. This descriptive study revealed that the representation of ‘psychiatry’ during summer 2012 was predominantly negative. A subsequent smaller re-ana...

  7. Nervous system examination on YouTube

    OpenAIRE

    Azer Samy A; AlEshaiwi Sarah M; AlGrain Hala A; AlKhelaif Rana A

    2012-01-01

    Abstract Background Web 2.0 sites such as YouTube have become a useful resource for knowledge and are used by medical students as a learning resource. This study aimed at assessing videos covering the nervous system examination on YouTube. Methods A research of YouTube was conducted from 2 November to 2 December 2011 using the following key words “nervous system examination”, “nervous system clinical examination”, “cranial nerves examination”, “CNS examination”, “examination of cerebellum”, “...

  8. Preparation of bioabsorbable nerve guide tubes.

    Science.gov (United States)

    Luciano, R M; de Carvalho Zavaglia, C A; de Rezende Duek, E A

    2000-03-01

    The use of bioabsorbable polymers in applications as temporary structural function, recovering damage in live tissues, is a promising research area. Membranes of poly(lactic acid) (PLA) may act as support to adhesion and cellular invasion or as devices for guided tissue regeneration (GTR). In this study, the same casting technique used to prepare membranes was used to prepare PLA tubes. These tubes can be used for tests in nerve guided regeneration (NGR). To improve flexibility of the device, a bioabsorbable plasticizer was added to the polymer. The initial results showed that the proposed technique allowed the preparation of flexible tubes that can be used for NGR. PMID:10759642

  9. Cyclotron resonance in a cathode ray tube

    International Nuclear Information System (INIS)

    Absorption of the RF energy by the electron beam in a cathode ray tube due to the cyclotron resonance is described. The cathode ray tube is placed within a Helmholtz coils system supplied by a sawtooth current generator. In order to generate RF field and to detect RF absorption a gate dip-meter equipped with a FET transistor is used. The bias voltage variations of the FET transistors as a function of the magnetic field are recorded. The operating point of the cathode ray tube has been chosen so that the relaxation oscillations of the detection system can be observed. (authors)

  10. Vulva cancer

    Science.gov (United States)

    Cancer - vulva; Cancer - perineum; Cancer - vulvar; Genital warts - vulvar cancer; HPV - vulvar cancer ... cells. Other types of cancers found on the vulva are: Adenocarcinoma Basal cell carcinoma Melanoma Sarcoma Vulvar ...

  11. Colon cancer

    Science.gov (United States)

    Colorectal cancer; Cancer - colon; Rectal cancer; Cancer - rectum; Adenocarcinoma - colon; Colon - adenocarcinoma ... In the United States, colorectal cancer is one of the leading causes of deaths due to cancer. Early diagnosis can often lead to a complete cure. Almost ...

  12. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Renal Cell) Cancer Leukemia Lung Cancer Lymphoma Pancreatic Cancer Prostate Cancer Skin Cancer Thyroid Cancer Uterine Cancer All ... Cancer Biology Cancer Genomics Causes of Cancer Diagnosis Prevention Screening & Early Detection Treatment Cancer & Public Health Cancer ...

  13. Tobacco and Cancer

    Science.gov (United States)

    ... Cancer? Breast Cancer Colon/Rectum Cancer Lung Cancer Prostate Cancer Skin Cancer Show All Cancer Types News and Features Cancer Glossary ACS Bookstore Cancer Information Cancer Basics Cancer Prevention & Detection Signs & Symptoms of Cancer Treatments & Side Effects ...

  14. Stages of Prostate Cancer

    Science.gov (United States)

    ... Renal Cell) Cancer Leukemia Lung Cancer Lymphoma Pancreatic Cancer Prostate Cancer Skin Cancer Thyroid Cancer Uterine Cancer All ... Cancer Treatment Prostate Cancer Prevention Genetics of Prostate Cancer Prostate Cancer Screening Research Prostate Cancer Treatment (PDQ®)–Patient ...

  15. Manufacturing and testing the HTGR refueling tube

    International Nuclear Information System (INIS)

    The paper describes the manufacturing technique for a refueling tube of a high-temperature gas-cooled nuclear reactor (HTGR). Four refueling tube sections were made: two sections from GSP-50 material and two sections from carbon-carbon (C-C) composite materials. Radiation tests were carried out in the reactor BOR-60. Experimental results show that the strength characteristics and thermophysical properties of graphitized carbon materials, from which the sections have been manufactured, are higher by a factor of 2.5-3.5 as compared with the HTGR refueling tube requirements. The dimensional changes of GSP-50 and C-C composite materials at temperatures between 300 and 600 deg C up to the neutron fluence of 1·1021 n/cm2 are comparable and meet the specifications for HTGR refueling tube

  16. Lava Tube Exploration Robot and Payload Development

    Science.gov (United States)

    Kelly, H. S.; Parness, A. J.; Boston, P. J.

    2015-10-01

    Merging science and engineering from the ground up to co-develop a comprehensive instrument/robot package for exploration of and scientific data collection within lava tubes that target analog sites on the Moon and Mars.

  17. Performance of a tapered pulse tube

    Energy Technology Data Exchange (ETDEWEB)

    Swift, G.; Allen, M.; Woolan, J.J. [Cryenco Inc., Denver, CO (United States)

    1998-02-01

    In a well instrumented pulse tube refrigerator having 1,500 W of cooling power at 125 K, the authors have measured the figure of merit of a tapered pulse tube at several operating points. At operating points near the operating point for which the taper was designed, the figure of merit is 0.96. This is close to the theoretical optimum figure of merit 0.97 calculated for this pulse tube considering only two loss mechanisms: heat conduction in the metal pulse tube wall and ordinary thermoacoustic heat transport in the gas within a few thermal penetration depths of the wall. At operating points farther from the design operating point, the measured figure of merit is much lower, as streaming driven convection adds a third loss mechanism.

  18. Water Oscillation in an Open Tube

    Directory of Open Access Journals (Sweden)

    Doh Hoon Chung

    2008-01-01

    Full Text Available When an open tube is placed in a tank of water, covered on top, raised, and then uncovered, the water inside the tube will oscillate. The characteristics of the oscillation of the water inside the tube were studied. It was shown that, for large oscillations, the top half-period was longer than the bottom half period due to the increased mass of the water column. For small oscillations, it approached simple harmonic motion, with the square of the period varying with mean length, as predicted by theory. An end correction was also shown to exist, due to the motion of the water outside the bottom of the tube during the oscillation. The end correction was shown to be independent of the mean length of the water column, as predicted.

  19. The Choking Game on YouTube

    Directory of Open Access Journals (Sweden)

    Ellen K. Defenderfer MS

    2016-03-01

    Full Text Available The choking game (TCG is an adolescent activity in which asphyxiation is used to obtain a “high,” occasionally resulting in seizures or death. A plethora of TCG information is available through YouTube, though this content has not been evaluated recently. The current study described TCG as portrayed in YouTube videos and compared views and ratings of TCG videos to unrelated videos. The TCG videos demonstrated diverse methods of asphyxiation, with a minority showing injury to the participants. TCG videos were less likely to be commented on or rated positively than non–choking game videos. TCG prevention videos differed significantly from actual TCG videos in the way they depicted the social context of TCG. Thus, TCG videos are accessible through YouTube, but the prevention materials available on YouTube are not accurate or representative. Accurate and educational online prevention materials should be created to decrease the occurrence of TCG.

  20. Staged multi-tube premixing injector

    Energy Technology Data Exchange (ETDEWEB)

    Zuo, Baifang; Khan, Abdul Rafey; York, William David; Ziminsky, Willy Steve

    2012-10-02

    A fuel injection nozzle includes a body member having an upstream wall opposing a downstream wall, and an internal wall disposed between the upstream wall and the downstream wall, a first chamber partially defined by the an inner surface of the upstream wall and a surface of the internal wall, a second chamber partially defined by an inner surface of the downstream wall and a surface of the internal wall a first gas inlet communicative with the first chamber operative to emit a first gas into the first chamber, a second gas inlet communicative with the second chamber operative to emit a second gas into the second chamber, and a plurality of mixing tubes, each of the mixing tubes having a tube inner surface, a tube outer surface, a first inlet communicative with an aperture in the upstream wall operative to receive a third gas.