Evaluation of a panel of antibodies for the immunohistochemical identification of immune cells in paraffin-embedded lymphoid tissues of new- and old-world camelids.

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Uhde, Ann-Kathrin; Lehmbecker, Annika; Baumgärtner, Wolfgang; Spitzbarth, Ingo

2017-02-01

Different species of camelids play an important role in the epidemiology of various emerging infectious diseases such as Middle East respiratory syndrome. For precise investigations of the immunopathogenesis in these host species, appropriate immunohistochemical markers are highly needed in order to phenotype distinct immune cells populations in camelids. So far, specific immunohistochemical markers for camelid immune cells are rarely commercially available, and cross-reactivity studies are restricted to the use of frozen dromedary tissues. To bridge this gap, 14 commercially available primary antibodies were tested for their suitability to demonstrate immune cell populations on formalin fixed paraffin-embedded (FFPE) tissue sections of dromedaries, Bactrian camels, llamas, and alpacas in the present study. Out of these, 9 antibodies directed against CD3, CD20, CD79α, HLA-DR, Iba-1, myeloid/histiocyte antigen, CD204, CD208, and CD68 antigen exhibited distinct immunoreaction patterns to certain camelid immune cell subsets. The distribution of these antigens was comparatively evaluated in different anatomical compartments of thymus, spleen, mesenteric, and tracheobronchial lymph nodes. The presented results will provide a basis for further investigations in camelids, especially with respect to the role of the immune response in certain infectious diseases, which harbor a considerable risk to spill over to other species. Copyright © 2017 Elsevier B.V. All rights reserved.

[Pathology of South American Camelids: a retrospective study of necropsies at the Institute of Veterinary Pathology, University of Leipzig, Germany].

Science.gov (United States)

Theuß, T; Goerigk, D; Rasenberger, S; Starke, A; Schoon, H-A

2014-01-01

The number of South American Camelids (New World Camelids) housed in Germany has increased in the recent years. While these species were formerly kept solely in zoological gardens, ever more private and commercial livestock is being established. Compared to indigenous livestock animals, they bear some distinctive differences, particularly in terms of digestive tract anatomy and physiology. Therefore, it is of considerable interest for veterinarians working with South American Camelids to obtain knowledge about the distinguishing features of these animals and the typical diseases affecting them in Germany. For this purpose, the necropsy reports, including the anamnestic data, and their diagnostic usefulness, from 1995 to 2012 were studied retrospectively. Du- ring this period, a total of 233 New World Camelids were examined (195 alpacas and 38 llamas). Anamnestic data of diagnostic usefulness regarding the cause of disease were only submitted in a limited number of cases, because most of the animals died without specific symptoms. The following were the most frequent pathological findings: enteritis (n = 91), gastritis (n = 76), cachexia (n = 73), pneumonia (n = 30), stomatitis (n = 27), azotaemia (n = 22) and anaemia (n = 9). An endoparasitosis occurred in 107 cases and was considered the predominant cause of enteritis. As with indigenous ruminants, llamas and alpacas primarily suffered from diseases of the digestive and respiratory tracts. Other organ systems were affected to a lesser extent. Even in cases with severe alterations in the affected organs, South American Camelids do not show or show too late diagnostically indicative clinical symptoms. Therefore, a detailed clinical examination of these animals is important.

Direct colloid osmometry in healthy New World camelids.

Science.gov (United States)

Quesada, Rolando J; Gorman, Maria Elena; Cebra, Christopher K; Verdugo, Claudio; Mosley, Craig A

2011-06-01

Direct colloid osmometry provides an objective assessment of the oncotic effects of crystalloid or colloidal fluid therapy, which is especially useful in monitoring fluid therapy of critically ill camelids due to their tendency toward nonspecific hypoproteinemia with increased risk of developing edema and ascites. The aims of this study were to measure colloid osmotic pressure (COP) of alpacas and llamas, determine its correlation with concentrations of total protein (TP) and total solids (TS), as well as both albumin (A) and globulin (G) concentrations in the same model (A+G), and evaluate the effects of sample type and storage conditions on COP. Blood was collected from clinically healthy alpacas (n=23) and llamas (n=22) into heparin tubes. COP of fresh whole blood (COP(FB) ) and plasma (COP(FP) ) was determined using a membrane osmometer. For 20 alpacas, COP of refrigerated whole blood (COP(RB) ) and frozen plasma (COP(FrP) ) was also measured. Correlations between COP(FB) and TS, TP, and A+G concentrations were assessed by simple and multiple regression analysis to model potential predictors. Median COP(FB) from alpacas (24.6 mmHg, range 19.3-28.1) was not significantly different from that of llamas (25.3 mmHg, range 22.5-33.7). Sample type or storage conditions did not affect COP. Measured COP had a strong positive linear correlation with TS, TP, and A+G concentrations in alpacas (r(2) =.7, .74, and .88, respectively). In llamas, COP correlated best with TS concentration (r(2) =.59), whereas correlation with TP and A+G concentrations was poor (r(2) =.19 and .25, respectively). COP can be measured using heparinized whole blood or plasma, either fresh or stored. Direct measurement is recommended whenever quantitative knowledge of COP is required in clinical or research setting. Further studies are needed to verify if the poor association of COP with TP found in this study can be generalized to llamas. ©2011 American Society for Veterinary Clinical Pathology.

Diagnosis of tuberculosis in camelids: old problems, current solutions and future challenges.

Science.gov (United States)

Alvarez, J; Bezos, J; Juan, L de; Vordermeier, M; Rodriguez, S; Fernandez-de-Mera, I G; Mateos, A; Domínguez, L

2012-02-01

In spite of great efforts for its control and eradication, tuberculosis remains one of the most important zoonosis worldwide. Its causative agents, the members of the Mycobacterium tuberculosis complex, have a wide host range that complicates the epidemiology of this disease. Among susceptible species to these pathogens, camelids from the New World (llama, alpaca and vicuña) and Old World (Bactrian camel and dromedary) are acquiring an increasing importance in several European countries because of its growing number and could act as reservoirs of the disease for livestock and humans in their natural habitat. In addition, tuberculosis caused by a number of M. tuberculosis complex members is a life-threatening disease in these animal species. Although tuberculosis has been known to affect camelids for a long time, ante-mortem diagnosis is still challenging because of the lack of standardized diagnostic techniques and the limited sensitivity and specificity of the most widely applied tests. However, in recent years, several techniques that can at least partially overcome these limitations have been developed. This paper reviews the results and advances achieved in tuberculosis diagnosis in camelids in the last decade as well as the progresses on ongoing investigations, with special attention to the remaining challenges that still have to be faced to assure the availability of reliable tools for the detection of tuberculosis-infected animals and herds. © 2011 Blackwell Verlag GmbH.

Oxygen binding properties, capillary densities and heart weights in high altitude camelids.

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Jürgens, K D; Pietschmann, M; Yamaguchi, K; Kleinschmidt, T

1988-01-01

The oxygen binding properties of the blood of the camelid species vicuna, llama, alpaca and dromedary camel were measured and evaluated with respect to interspecific differences. The highest blood oxygen affinity, not only among camelids but of all mammals investigated so far, was found in the vicuna (P50 = 17.6 Torr compared to 20.3-21.6 Torr in the other species). Low hematocrits (23-34%) and small red blood cells (21-30 microns 3) are common features of all camelids, but the lowest values are found in the Lama species. Capillary densities were determined in heart and soleus muscle of vicuna and llama. Again, the vicuna shows exceptional values (3720 cap/mm2 on average in the heart) for a mammal of this body size. Finally, heart weight as percent of body weight is higher in the vicuna (0.7-0.9%) than in the other camelids studied (0.5-0.7%). The possibility that these parameters, measured in New World tylopodes at sea level, are not likely to change considerably with transfer to high altitude, is discussed. In the vicuna, a unique combination of the following features seems to be responsible for an outstanding physical capability at high altitude: saturation of blood with oxygen in the lung is favored by a high blood oxygen affinity, oxygen supply being facilitated by low diffusion distances in the muscle tissue. Loading, as well as unloading, of oxygen is improved by a relatively high oxygen transfer conductance of the red blood cells, which is due to their small size and which compensates the negative effect of a low hematocrit on the oxygen conductance of blood.(ABSTRACT TRUNCATED AT 250 WORDS)

Approach to the critically ill camelid.

Science.gov (United States)

Bedenice, Daniela

2009-07-01

The estimation of fluid deficits in camelids is challenging. However, early recognition and treatment of shock and hypovolemia is instrumental to improve morbidity and mortality of critically ill camelids. Early goal-directed fluid therapy requires specific knowledge of clinical indicators of hypovolemia and assessment of resuscitation endpoints, but may significantly enhance the understanding, monitoring, and safety of intravenous fluid therapy in South American camelids (SAC). It is important to recognize that over-aggressive fluid resuscitation is just as detrimental as under resuscitation. Nonetheless, a protocol of conservative fluid management is often indicated in the treatment of camelids with pulmonary inflammation, to counteract edema formation. The early recognition of lung dysfunction is often based on advanced diagnostic techniques, including arterial blood gas analysis, diagnostic imaging, and noninvasive pulmonary function testing.

Cerebrospinal Nematodiasis in 20 Camelids

OpenAIRE

Bertin, F.R.; Taylor, S.D.

2016-01-01

Background Information about the clinical and clinicopathologic aspects of cerebrospinal nematodiasis (CN) in camelids is limited. Hypothesis Clinical and therapeutic variables will be identified as factors predictive of survival. Animals Client?owned camelids suspected of having CN admitted to Purdue University between 1995 and 2015. Methods A retrospective study was performed. A diagnosis of CN was based on cerebrospinal fluid (CSF) eosinophilic pleocytosis or postmortem findings. Results E...

Cerebrospinal Nematodiasis in 20 Camelids.

Science.gov (United States)

Bertin, F R; Taylor, S D

2016-07-01

Information about the clinical and clinicopathologic aspects of cerebrospinal nematodiasis (CN) in camelids is limited. Clinical and therapeutic variables will be identified as factors predictive of survival. Client-owned camelids suspected of having CN admitted to Purdue University between 1995 and 2015. A retrospective study was performed. A diagnosis of CN was based on cerebrospinal fluid (CSF) eosinophilic pleocytosis or postmortem findings. Eleven alpacas and 9 llamas met the inclusion criteria. Seventy-five percent of the camelids were male (27% castrated and 73% intact). Common clinical abnormalities included proprioceptive deficits (100% of animals), recumbency (55%), tachypnea (55%), and ataxia (40%). Among the 85% of treated animals, 100% received PO fenbendazole, and 88% received a nonsteroidal anti-inflammatory drug. The survival rate to discharge was 45%. Plasma fibrinogen concentration, creatine kinase activity, and serum creatinine concentration were significantly higher in nonsurvivors. Blood eosinophil count, platelet count, and total CO2 were significantly lower in nonsurvivors. Factors associated with survival were species, sex, absence of treatment with corticosteroids, and clinical improvement. There was no association between recumbency at admission and survival. A plasma fibrinogen concentration above >266 mg/dL was an excellent diagnostic test to predict survival in the presence of neurological signs or CSF eosinophilia. Although prognosis for CN in camelids is guarded, presence of recumbency at admission is not predictive of nonsurvival. Male camelids and llamas appear more likely to die from CN. Corticosteroid treatment is contraindicated in animals diagnosed with CN. Copyright © 2016 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

An introduction to South American camelids

International Nuclear Information System (INIS)

Urquieta, B.; Rojas, J.R.

1990-01-01

The South American camelids - the domesticated alpaca and llama, and the wild vicuna and guanaco - which belong to the Camelidae family of the Artiodactyla order are of considerable sociological, economic and ecological importance to the native populations living in the high plateau (altiplano) of the central Andes. Owing to their biological characteristics they are able to provide meat, wool, hides and transportation without disrupting the fragile ecosystem. Increasing interest is being taken in these animals, both in their native lands of Argentina, Bolivia, Chile and Peru and in other parts of the world. (author). 55 refs, 5 figs

Haemotrophic mycoplasmas in South American camelids in Switzerland

OpenAIRE

Kaufmann, C; Meli, Marina L; Robert, N; Willi, Barbara; Hofmann-Lehmann, Regina; Wengi, Nicole; Lutz, Hans; Zanolari, P

2007-01-01

The red blood cell parasite 'Candidatus Mycoplasma haemolamae', formerly Eperythrozoon, is known to be widespread in South American camelids in the USA, causing anaemia in affected animals. Up to now, haemotrophic mycoplasmas were not observed in South American camelids in Europe; however, they were known in a herd of alpacas in Switzerland and to identify them as 'Candidatus M. haemolamae'. Possible ways of transmission are discussed.

[Endo- and ectoparasites of South American camelids and their control].

Science.gov (United States)

Schmäschke, R

2015-01-01

In a literature review, common endo- and ectoparasites of South American camelids are described, presenting morphological details and clinical signs important for diagnosis. Based on the life cycle of the parasites, possibilities for prophylaxis and therapy are indicated. The review should aid the veterinarian to diagnose and control common parasitic infections in South American camelids.

Vascular provisions for a local utero-ovarian cross-over pathway in new world camelids.

Science.gov (United States)

Del Campo, M R; Del Campo, C H; Ginther, O J

1996-10-15

The right uterine horn of alpacas causes luteolysis in the right ovary, whereas the left horn causes luteolysis in both ovaries. Female reproductive tracts were studied in 32 adult llamas, 12 adult alpacas, and 21 mid-gestation female fetuses to determine if there is a dichotomy in the vascular anatomy between the 2 sides. Adult tracts were studied by either injection of colored latex into the veins and arteries followed by tissue clearing or by injection of colored fluids during transillumination. Fetal uteri were studied by transillumination. The angioarchitecture of the ovarian vascular pedicle was similar to that reported for ewes. There was no vessel comparable to the middle uterine artery, which is the largest uterine artery in the other farm species. A striking difference from the uterine vascular of other farm species was the presence of a major branch of the right uterine artery that crossed the cranial intercornual area to supply much of the left uterine horn. A corresponding major vein originated from the left horn, crossed the mid-line, and terminated as a branch of the right uterine vein. Thus, the vascular anatomy indicated that much venous blood from the left horn drained to the right side. This was confirmed by injection of colored fluid into a small venous branch at the tip of the left horn. The prominent cross-over vessels were observed in the fetal uteri, and the diameter of the left uterine fetal horn (6.7 +/- 0.6 mm) was greater (P blood from the left horn into an artery supplying the right ovary was not defined in this study. However, the results provide an anatomical basis for functional testing of the cross-over hypothesis and defining the area of venoarterial transfer in camelids.

Camelid Single-Domain Antibodies: Historical Perspective and Future Outlook

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Mehdi Arbabi-Ghahroudi

2017-11-01

Full Text Available Tremendous effort has been expended over the past two and a half decades to understand many aspects of camelid heavy chain antibodies, from their biology, evolution, and immunogenetics to their potential applications in various fields of research and medicine. In this article, I present a historical perspective on the development of camelid single-domain antibodies (sdAbs or VHHs, also widely known as nanobodies since their discovery and discuss the advantages and disadvantages of these unique molecules in various areas of research, industry, and medicine. Commercialization of camelid sdAbs exploded in 2001 with a flurry of patents issued to the Vrije Universiteit Brussel (VUB and later taken on by the Vlaams Interuniversitair Instituut voor Biotechnologie (VIB and, after 2002, the VIB-founded spin-off company, Ablynx. While entrepreneurial spirit has certainly catalyzed the exploration of nanobodies as marketable products, IP restrictions may be partially responsible for the relatively long time span between the discovery of these biomolecules and their entry into the pharmaceutical market. It is now anticipated that the first VHH-based antibody drug, Caplacizumab, a bivalent anti-vWF antibody for treating rare blood clotting disorders, may be approved and commercialized in 2018 or shortly thereafter. This elusive first approval, along with the expiry of key patents, may substantially alter the scientific and biomedical landscape surrounding camelid sdAbs and pave the way for their emergence as mainstream biotherapeutics.

Evaluation of insulin resistance in two kinds of South American camelids: llamas and alpacas.

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Araya, A V; Atwater, I; Navia, M A; Jeffs, S

2000-10-01

Insulin resistance was evaluated in South American camelids, llamas and alpacas, by use of the minimal model test and the insulin tolerance test. Animals were catheterized for long-term studies and tamed to minimize stress during evaluation. Results indicated a low insulin sensitivity index (SI) = 0 to 0.97, median = 0.39 x 10(-4) min/uIU x ml, about a fifth the value in other mammals and humans. The KITT was between 1.43 and 3.19 %/min, also significantly lower than that reported for humans. Glycosylated hemoglobin concentration was 6%, and HbAlc concentration was 5.5%; red blood cell lifetime, as measured by use of the 51Cr method, was 120 days, similar to the value in humans. We concluded that llamas and alpacas have naturally higher blood glucose concentration than do humans and other mammals during the glucose tolerance test. Using the same mathematical tools to evaluate glucose metabolism as those used in people, South American camelids appear to be resistant to insulin. Thus, the South American camelid may be a useful new animal model for the study of sugar metabolism and various facets of diabetes mellitus, especially protection from the deleterious effects of glycosylation.

Construction of naïve camelids VHH repertoire in phage display-based library.

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Sabir, Jamal S M; Atef, Ahmed; El-Domyati, Fotouh M; Edris, Sherif; Hajrah, Nahid; Alzohairy, Ahmed M; Bahieldin, Ahmed

2014-04-01

Camelids have unique antibodies, namely HCAbs (VHH) or commercially named Nanobodies(®) (Nb) that are composed only of a heavy-chain homodimer. As libraries based on immunized camelids are time-consuming, costly and likely redundant for certain antigens, we describe the construction of a naïve camelid VHHs library from blood serum of non-immunized camelids with affinity in the subnanomolar range and suitable for standard immune applications. This approach is rapid and recovers VHH repertoire with the advantages of being more diverse, non-specific and devoid of subpopulations of specific antibodies, which allows the identification of binders for any potential antigen (or pathogen). RNAs from a number of camelids from Saudi Arabia were isolated and cDNAs of the diverse vhh gene were amplified; the resulting amplicons were cloned in the phage display pSEX81 vector. The size of the library was found to be within the required range (10(7)) suitable for subsequent applications in disease diagnosis and treatment. Two hundred clones were randomly selected and the inserted gene library was either estimated for redundancy or sequenced and aligned to the reference camelid vhh gene (acc. No. ADE99145). Results indicated complete non-specificity of this small library in which no single event of redundancy was detected. These results indicate the efficacy of following this approach in order to yield a large and diverse enough gene library to secure the presence of the required version encoding the required antibodies for any target antigen. This work is a first step towards the construction of phage display-based biosensors useful in disease (e.g., TB or tuberculosis) diagnosis and treatment. Copyright © 2014 Académie des sciences. Published by Elsevier SAS. All rights reserved.

Development and Application of Camelid Molecular Cytogenetic Tools

Science.gov (United States)

Avila, Felipe; Das, Pranab J.; Kutzler, Michelle; Owens, Elaine; Perelman, Polina; Rubes, Jiri; Hornak, Miroslav; Johnson, Warren E.

2014-01-01

Cytogenetic chromosome maps offer molecular tools for genome analysis and clinical cytogenetics and are of particular importance for species with difficult karyotypes, such as camelids (2n = 74). Building on the available human–camel zoo-fluorescence in situ hybridization (FISH) data, we developed the first cytogenetic map for the alpaca (Lama pacos, LPA) genome by isolating and identifying 151 alpaca bacterial artificial chromosome (BAC) clones corresponding to 44 specific genes. The genes were mapped by FISH to 31 alpaca autosomes and the sex chromosomes; 11 chromosomes had 2 markers, which were ordered by dual-color FISH. The STS gene mapped to Xpter/Ypter, demarcating the pseudoautosomal region, whereas no markers were assigned to chromosomes 14, 21, 22, 28, and 36. The chromosome-specific markers were applied in clinical cytogenetics to identify LPA20, the major histocompatibility complex (MHC)-carrying chromosome, as a part of an autosomal translocation in a sterile male llama (Lama glama, LGL; 2n = 73,XY). FISH with LPAX BACs and LPA36 paints, as well as comparative genomic hybridization, were also used to investigate the origin of the minute chromosome, an abnormally small LPA36 in infertile female alpacas. This collection of cytogenetically mapped markers represents a new tool for camelid clinical cytogenetics and has applications for the improvement of the alpaca genome map and sequence assembly. PMID:23109720

Digesta retention patterns of solute and different-sized particles in camelids compared with ruminants and other foregut fermenters.

Science.gov (United States)

Dittmann, Marie T; Runge, Ullrich; Ortmann, Sylvia; Lang, Richard A; Moser, Dario; Galeffi, Cordula; Schwarm, Angela; Kreuzer, Michael; Clauss, Marcus

2015-07-01

The mean retention times (MRT) of solute or particles in the gastrointestinal tract and the forestomach (FS) are crucial determinants of digestive physiology in herbivores. Besides ruminants, camelids are the only herbivores that have evolved rumination as an obligatory physiological process consisting of repeated mastication of large food particles, which requires a particle sorting mechanism in the FS. Differences between camelids and ruminants have hardly been investigated so far. In this study we measured MRTs of solute and differently sized particles (2, 10, and 20 mm) and the ratio of large-to-small particle MRT, i.e. the selectivity factors (SF(10/2mm), SF(20/2mm), SF(20/10mm)), in three camelid species: alpacas (Vicugna pacos), llamas (Llama glama), and Bactrian camels (Camelus bactrianus). The camelid data were compared with literature data from ruminants and non-ruminant foregut fermenters (NRFF). Camelids and ruminants both had higher SF(10/2mm)FS than NRFF, suggesting convergence in the function of the FS sorting mechanism in contrast to NRFF, in which such a sorting mechanism is absent. The SF(20/10mm)FS did not differ between ruminants and camelids, indicating that there is a particle size threshold of about 1 cm in both suborders above which particle retention is not increased. Camelids did not differ from ruminants in MRT(2mm)FS, MRTsoluteFS, and the ratio MRT(2mm)FS/MRTsoluteFS, but they were more similar to 'cattle-' than to 'moose-type' ruminants. Camelids had higher SF(10/2mm)FS and higher SF(20/2mm)FS than ruminants, indicating a potentially slower particle sorting in camelids than in ruminants, with larger particles being retained longer in relation to small particles.

South American camelid illegal traffic detection by means of molecular markers.

Science.gov (United States)

Di Rocco, F; Posik, D M; Ripoli, M V; Díaz, S; Maté, M L; Giovambattista, G; Vidal-Rioja, L

2011-11-01

South American camelids comprise the wild species guanaco and vicuña and their respective domestic relatives llama and alpaca. The aim of the present study was to determine by DNA analysis to which of these species belong a herd of camelids confiscated from a llama breeder but alleged to be alpacas by the prosecution, and to evaluate the usefulness of mitochondrial and autosomal DNA markers to solve judicial cases involving camelid taxa. Cytochrome b and cytochrome oxidase I mitochondrial genes and 7 STR were analyzed in 25 confiscated samples. Mitochondrial results were inconclusive because 18 of the sequestered samples presented haplotypes that corresponded to the guanaco haplogroup and the remaining seven belonged to a vicuña linage. Microsatellite data of casework samples and llama reference samples revealed different genetic profiles by the presence of private alleles at two microsatellites suggesting that the confiscated animals could be alpaca, or at least alpaca hybrids instead of pure llama. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Comparison of invasive and oscillometric blood pressure measurement techniques in anesthetized camelids.

Science.gov (United States)

Aarnes, Turi K; Hubbell, John A E; Lerche, Phillip; Bednarski, Richard M

2012-08-01

This study assessed the accuracy of the oscillometric method for arterial blood pressure (ABP) monitoring in anesthetized camelids. Twenty camelids were anesthetized and systolic ABP (SABP), mean ABP (MABP), and diastolic ABP (DABP) were measured directly and using the oscillometric method. The mean difference between SABP measurements was -9.9 ± 21.9 mmHg with a range of -76 to 54 mmHg, and the 95% limits of agreement (LOA) were -33 to 53 mmHg. The difference between DABP measurements was -1.8 ± 15.6 mmHg with a range of -81 to 36 mmHg, and the 95% LOA were -32 to 29 mmHg. The difference between MABP measurements was -2.9 ± 17.0 mmHg with a range of -81 to 36 mmHg, and the 95% LOA were -30 to 36 mmHg. Accurate ABP monitoring in anesthetized camelids cannot be accomplished using the oscillometric method.

Brightness of venous blood in South American camelids: implications for jugular catheterization.

Science.gov (United States)

Grint, Nicola; Dugdale, Alexandra

2009-01-01

To compare the brightness of South American camelid venous blood to that of Equidae. Prospective clinical evaluation. Twelve South American camelids (eight llamas, four alpacas), eight horses and ponies (control group). Appropriately sized catheters were placed in the jugular vein of each animal under local anaesthesia. The blood spilt before the catheter was capped was caught on a white tile. A sample of blood was drawn for blood-gas analysis. The brightness of the blood (both on the tile and in the syringe) was matched to a colour chart (1 = darkest red, 8 = brightest red) by a single observer under bright light conditions. Packed cell volume (PCV) and partial pressure of oxygen (PvO(2)) in the blood were also measured on the syringe blood. Normally distributed data were compared using a two tailed t-test, and non-normally distributed data were compared using a Mann-Whitney U-test. Significance was set at p Camelid venous blood was significantly brighter red than that of horses and ponies both on the white tile (p = 0.0003) and in the syringe (p = 0.0001). PCV was significantly lower in camelids (32 +/- 4%) compared with horses (37 +/- 5%). Partial pressure of oxygen values were similar between groups. Jugular venous blood in alpacas and llamas is significantly brighter red than that of horses. Colour should not be used as a sole determinant of venous or arterial catheterization in this species.

Comparison of invasive and oscillometric blood pressure measurement techniques in anesthetized camelids

OpenAIRE

Aarnes, Turi K.; Hubbell, John A.E.; Lerche, Phillip; Bednarski, Richard M.

2012-01-01

This study assessed the accuracy of the oscillometric method for arterial blood pressure (ABP) monitoring in anesthetized camelids. Twenty camelids were anesthetized and systolic ABP (SABP), mean ABP (MABP), and diastolic ABP (DABP) were measured directly and using the oscillometric method. The mean difference between SABP measurements was −9.9 ± 21.9 mmHg with a range of −76 to 54 mmHg, and the 95% limits of agreement (LOA) were −33 to 53 mmHg. The difference between DABP measurements was −1...

Biomechanical analysis of the camelid cervical intervertebral disc

Directory of Open Access Journals (Sweden)

Dean K. Stolworthy

2015-01-01

Full Text Available Chronic low back pain (LBP is a prevalent global problem, which is often correlated with degenerative disc disease. The development and use of good, relevant animal models of the spine may improve treatment options for this condition. While no animal model is capable of reproducing the exact biology, anatomy, and biomechanics of the human spine, the quality of a particular animal model increases with the number of shared characteristics that are relevant to the human condition. The purpose of this study was to investigate the camelid (specifically, alpaca and llama cervical spine as a model of the human lumbar spine. Cervical spines were obtained from four alpacas and four llamas and individual segments were used for segmental flexibility/biomechanics and/or morphology/anatomy studies. Qualitative and quantitative data were compared for the alpaca and llama cervical spines, and human lumbar specimens in addition to other published large animal data. Results indicate that a camelid cervical intervertebral disc (IVD closely approximates the human lumbar disc with regard to size, spinal posture, and biomechanical flexibility. Specifically, compared with the human lumbar disc, the alpaca and llama cervical disc size are approximately 62%, 83%, and 75% with regard to area, depth, and width, respectively, and the disc flexibility is approximately 133%, 173%, and 254%, with regard to range of motion (ROM in axial-rotation, flexion-extension, and lateral-bending, respectively. These results, combined with the clinical report of disc degeneration in the llama lower cervical spine, suggest that the camelid cervical spine is potentially well suited for use as an animal model in biomechanical studies of the human lumbar spine.

Biochemical adaptation of camelids during periods where feed is withheld

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J. Wensvoort

2001-03-01

Full Text Available Biochemical changes during fasting or the withholding of feed for 5 day were studied in serum of camelids (dromedary camel, llama and ruminants (sheep, steers. Camels maintained low levels of 13-hydroxybutyrate (BHB and high levels of glucose but showed some increased levels of non-esterified fatty acid (NEFA and urea when fasting. Sheep and steers showed a rise in serum BHB and much higher increases of NEFA than camels and llamas. Sheep showed decreased serum glucose. The llama showed some increase in BHB but NEFA was lower than the other three species. The results indicate that camelids have a unique ability to control lipolytic and gluconeogenic activity to prevent or postpone the state of ketosis. Understanding and manipulation of these metabolic mechanisms in cattle and sheep could have great benefit to the livestock industry.

Properties, production and applications of camelid single-domain antibody fragments

NARCIS (Netherlands)

Harmsen, M.M.; Haard, de H.J.

2007-01-01

Camelids produce functional antibodies devoid of light chains of which the single N-terminal domain is fully capable of antigen binding. These single-domain antibody fragments (VHHs or Nanobodies®) have several advantages for biotechnological applications. They are well expressed in microorganisms

Determination of Testicular Blood Flow in Camelids Using Vascular Casting and Color Pulsed-Wave Doppler Ultrasonography

OpenAIRE

Kutzler, Michelle; Tyson, Reid; Grimes, Monica; Timm, Karen

2011-01-01

We describe the vasculature of the camelid testis using plastic casting. We also use color pulsed-wave Doppler ultrasonography to measure testicular blood flow and compare the differences between testicular blood flow in fertile and infertile camelids. The testicular artery originates from the ventral surface of the aorta, gives rise to an epididymal branch, and becomes very tortuous as it approaches the testis. Within the supratesticular arteries, peak systolic velocity (PSV) was higher in f...

OSTEOMETRÍA Y GENÉTICA DE LOS CAMÉLIDOS MOCHICA, COSTA NORTE DEL PERÚ / Mochica camelids osteometry and genetics, north coast of Peru

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Víctor Félix Vásquez Sánchez

2009-12-01

of Peru during Moche times. This model takes into account that in this environment currently camelids are not breed, as well as genetics and evolutionary factors in the new domestic form, the effect of Bergmann’s Rule, and new grasses in the morphology of this new form of domestic camelid, ,which lived in the region at the time of Moche.Keywords: osteometry, genetic, camelids, speciation, Mochica 

Fluid therapy in small ruminants and camelids.

Science.gov (United States)

Jones, Meredyth; Navarre, Christine

2014-07-01

Body water, electrolytes, and acid-base balance are important considerations in the evaluation and treatment of small ruminants and camelids with any disease process, with restoration of these a priority as adjunctive therapy. The goals of fluid therapy should be to maintain cardiac output and tissue perfusion, and to correct acid-base and electrolyte abnormalities. Hypoglycemia, hyperkalemia, and acidosis are the most life-threatening abnormalities, and require most immediate correction. Copyright © 2014 Elsevier Inc. All rights reserved.

A proof of concept study to assess the potential of PCR testing to detect natural Mycobacterium bovis infection in South American camelids.

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Crawshaw, Timothy R; Chanter, Jeremy I; McGoldrick, Adrian; Line, Kirsty

2014-02-07

Cases of Mycobacterium bovis infection South American camelids have been increasing in Great Britain. Current antemortem immunological tests have some limitations. Cases at post mortem examination frequently show extensive pathology. The feasibility of detecting Mycobacterium bovis DNA in clinical samples was investigated. A sensitive extraction methodology was developed and used on nasal swabs and faeces taken post-mortem to assess the potential for a PCR test to detect Mycobacterium bovis in clinical samples. The gross pathology of the studied South American camelids was scored and a significantly greater proportion of South American camelids with more severe pathology were positive in both the nasal swab and faecal PCR tests. A combination of the nasal swab and faecal PCR tests detected 63.9% of all the South American camelids with pathology that were tested. The results suggest that antemortem diagnosis of Mycobacterium bovis in South American camelids may be possible using a PCR test on clinical samples, however more work is required to determine sensitivity and specificity, and the practicalities of applying the test in the field.

Arthroscopic approach and intraarticular anatomy of the stifle in South American camelids.

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Pentecost, Rebecca L; Niehaus, Andrew J; Santschi, Elizabeth

2012-05-01

To describe a cranial arthroscopic approach to the stifle of South American camelids and to report our clinical experience with camelid stifle arthroscopy. Experimental study and retrospective case series. (1) Cadaveric alpaca hindlimbs (n = 18; 9 alpacas); (2) 1 alpaca and 1 llama Polymethylmethacrylate joint casts (n = 2) were made to define stifle joint dimensions. Cadaveric stifle joints (n = 16) were evaluated arthroscopically to determine arthroscopic portal locations, describe the intraarticular anatomy, and report potential complications. An alpaca and a llama with stifle joint disease had diagnostic arthroscopy. Successful entry into the stifle joint was achieved in 16 cadaver limbs. Observed structures were: the suprapatellar pouch, articular surface of the patella, femoral trochlear ridges and groove, cranial aspect of the femoral condyles (n = 16); distal aspect of the cranial and proximal aspect of the caudal cruciate ligaments (14); and cranial aspects of the medial and lateral menisci (11), and cranial meniscotibial and intermeniscal ligaments (8). Stifle arthroscopy allowed for joint evaluation and removal of osteochondral fragments in 1 alpaca and 1 llama with naturally occurring stifle disease. Complications of cadaver or live procedures included minor cartilage scoring (3 stifles) and subcutaneous periarticular fluid accumulation (8 stifles). Arthroscopy provides a safe approach for diagnosis and treatment of stifle lesions in South American camelids. Copyright 2012 by The American College of Veterinary Surgeons.

Generation of single domain antibody fragments derived from camelids and generation of manifold constructs.

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Vincke, Cécile; Gutiérrez, Carlos; Wernery, Ulrich; Devoogdt, Nick; Hassanzadeh-Ghassabeh, Gholamreza; Muyldermans, Serge

2012-01-01

Immunizing a camelid (camels and llamas) with soluble, properly folded proteins raises an affinity-matured immune response in the unique camelid heavy-chain only antibodies (HCAbs). The peripheral blood lymphocytes of the immunized animal are used to clone the antigen-binding antibody fragment from the HCAbs in a phage display vector. A representative aliquot of the library of these antigen-binding fragments is used to retrieve single domain antigen-specific binders by successive rounds of panning. These single domain antibody fragments are cloned in tandem to generate manifold constructs (bivalent, biparatopic or bispecific constructs) to increase their functional affinity, to increase specificity, or to connect two independent antigen molecules.

[Reproductive physiology in New World camelids. Review].

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Gauly, M

1997-01-01

Liamas and alpacas have gained international popularity over the last years. Therefore veterinarians are often asked to intervene in clinical management of different problems, especially reproductive problems. In this review the author attempts to summarize the material presented on the reproductive anatomy, physiology, behavior, embryo transfer and artificial insemination procedure of these animals.

Validation of the FAMACHA© system in South American camelids.

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Storey, Bobby E; Williamson, Lisa H; Howell, Sue B; Terrill, Thomas H; Berghaus, Roy; Vidyashankar, Anand N; Kaplan, Ray M

2017-08-30

Haemonchus contortus resistant to multiple anthelmintics threaten the viability of the small ruminant industry in areas where this parasite is prevalent. In response to this situation, the FAMACHA© system was developed and validated for use with small ruminants as a way to detect clinical anemia associated with haemonchosis. Given that H. contortus and multiple anthelmintic resistance is a similar problem in camelids, the FAMACHA© system might also provide the same benefits. To address this need, a validation study of the FAMACHA© system was conducted on 21 alpaca and llama farms over a 2-year period. H. contortus was the predominant nematode parasite on 17 of the 21 farms (10 alpaca and 7 llama farms) enrolled in the study, based on fecal culture results. The FAMACHA© card was used to score the color of the lower palpebral (lower eye lid) conjunctiva on a 1-5 scale. Packed cell volume (PCV) values were measured and compared to FAMACHA© scores using FAMACHA© score cutoffs of ≥3 or ≥4 and with anemia defined as a PCV ≤15%, ≤17%, or≤20%. PCV was significantly associated with FAMACHA© score, fecal egg count (FEC), and body condition score (BCS), regardless of the FAMACHA© cutoff score or the PCV% chosen to define clinical anemia (p<0.01 in all cases). The use of FAMACHA© scores ≥3 and PCV ≥ 15% indicating anemia provided the best sensitivity (96.4% vs 92.9% for FAMACHA© ≥4), whereas FAMACHA scores ≥ 4 and PCV ≤20% provided the best specificity (94.2% vs 69.1% for FAMACHA© ≥3). The data from this study support the FAMACHA© system as a useful tool for detecting clinical anemia in camelids suffering from haemonchosis. Parameters for making treatment decisions based on FAMACHA© score in camelids should mirror those established for small ruminants. Copyright © 2017 Elsevier B.V. All rights reserved.

Low habitat overlap at landscape scale between wild camelids and feral donkeys in the Chilean desert

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Malo, Juan E.; González, Benito A.; Mata, Cristina; Vielma, André; Donoso, Denise S.; Fuentes, Nicolás; Estades, Cristián F.

2016-01-01

Feral domestic ungulates may compete with the populations of wild herbivores with which they coexist, particularly so in arid regions. The potential competition between wild camelids and feral donkeys at the eastern sector of the Atacama Desert is evaluated in terms of their coincidence or segregation in habitat use and complemented with a comparison of reproductive output (yearling/adult ratio) of vicuña family groups in the proximity vs. distant from donkey observations. Habitat use of wild camelids and donkeys was sampled driving some 1250 km of roads and tracks at the dry and wet seasons. There were 221 vicuñas (Vicugna vicugna) sightings, 77 for donkeys (Equus asinus), 25 for guanacos (Lama guanicoe) and 8 for hybrids between guanacos and domestic llamas (Lama glama), as well as 174 randomly selected control locations. By means of Generalised Discriminant Analysis and Analysis of Variance we show that all ungulates actively select their habitat, with significant differences between use and availability in the area. Donkeys are relatively abundant in comparison with camelids and coincide broadly with both of them across the altitudinal gradient, but they fall between them in local scale habitat selection and do not seem to force their displacement from their preferred habitats. Thus donkeys occur preferentially on slopes with a high cover of tall shrubs, whereas vicuñas use valley bottoms with grass and guanacos the upper slope zones with grass. The potential for competition between donkeys and wild camelids is thus limited and it does not affect the reproductive output of vicuña in this region. Therefore, with the present knowledge we suggest that population control is not currently merited for feral donkeys.

Determination of testicular blood flow in camelids using vascular casting and color pulsed-wave Doppler ultrasonography.

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Kutzler, Michelle; Tyson, Reid; Grimes, Monica; Timm, Karen

2011-01-01

We describe the vasculature of the camelid testis using plastic casting. We also use color pulsed-wave Doppler ultrasonography to measure testicular blood flow and compare the differences between testicular blood flow in fertile and infertile camelids. The testicular artery originates from the ventral surface of the aorta, gives rise to an epididymal branch, and becomes very tortuous as it approaches the testis. Within the supratesticular arteries, peak systolic velocity (PSV) was higher in fertile males compared to infertile males (P = 0.0004). In addition, end diastolic velocity (EDV) within the supratesticular arteries was higher for fertile males when compared to infertile males (P = 0.0325). Within the marginal arteries, PSV was also higher in fertile males compared to infertile males (P = 0.0104). However, EDV within the marginal arteries was not significantly different between fertile and infertile males (P = 0.121). In addition, the resistance index was not significantly different between fertile and infertile males within the supratesticular (P = 0.486) and marginal arteries (P = 0.144). The significance of this research is that in addition to information obtained from a complete reproductive evaluation, a male camelid's fertility can be determined using testicular blood flow measured by Doppler ultrasonography.

Determination of Testicular Blood Flow in Camelids Using Vascular Casting and Color Pulsed-Wave Doppler Ultrasonography

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Michelle Kutzler

2011-01-01

Full Text Available We describe the vasculature of the camelid testis using plastic casting. We also use color pulsed-wave Doppler ultrasonography to measure testicular blood flow and compare the differences between testicular blood flow in fertile and infertile camelids. The testicular artery originates from the ventral surface of the aorta, gives rise to an epididymal branch, and becomes very tortuous as it approaches the testis. Within the supratesticular arteries, peak systolic velocity (PSV was higher in fertile males compared to infertile males (P=0.0004. In addition, end diastolic velocity (EDV within the supratesticular arteries was higher for fertile males when compared to infertile males (P=0.0325. Within the marginal arteries, PSV was also higher in fertile males compared to infertile males (P=0.0104. However, EDV within the marginal arteries was not significantly different between fertile and infertile males (P=0.121. In addition, the resistance index was not significantly different between fertile and infertile males within the supratesticular (P=0.486 and marginal arteries (P=0.144. The significance of this research is that in addition to information obtained from a complete reproductive evaluation, a male camelid's fertility can be determined using testicular blood flow measured by Doppler ultrasonography.

Oxygen transfer properties and dimensions of red blood cells in high-altitude camelids, dromedary camel and goat.

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Yamaguchi, K; Jürgens, K D; Bartels, H; Piiper, J

1987-01-01

To estimate the advantage of the small red blood cells (RBC) of high-altitude camelids for O2 transfer, the kinetics of O2 uptake into and release from the RBC obtained from llama, vicuña and alpaca were investigated at 37 degrees C with a stopped-flow technique. O2 transfer conductance of RBC (G) was estimated from the rate of O2 saturation change and the corresponding O2 pressure difference between medium and hemoglobin. For comparison, O2 kinetics for the RBC of a low-altitude camelid (dromedary camel) and the pygmy goat were determined and previously measured values for human RBC were used. O2 transfer of RBC was found to be strongly influenced by extracellular diffusion, except with O2 release into dithionite solutions of sufficiently high concentration (greater than 30 mM). The G values measured in these 'standard' conditions, Gst (in mmol X min-1 X Torr-1 X (ml RBC)-1) were: high-altitude camelids, 0.58 (averaged for llama, alpaca and vicuña since there were no significant interspecific differences); camel 0.42; goat, 0.42; man, 0.39. The differences can in part be attributed to expected effects of the size and shape of the RBC (volume, surface area, mean thickness), as well as to the intracellular O2 diffusivity which depends on the concentration of cellular hemoglobin. The high Gst of RBC of high-altitude camelids may be considered to enhance O2 transfer in lungs and tissues. But the O2 transfer conductance of blood, theta, equal to Gst multiplied by hematocrit (in mmol X min-1 X Torr-1 X (ml blood)-1), was only slightly higher as compared to other species: 0.20 (llama, alpaca, vicuña), 0.14 (camel), 0.18 (goat), 0.17 (man).

Prediction of Packed Cell Volume after Whole Blood Transfusion in Small Ruminants and South American Camelids: 80 Cases (2006-2016).

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Luethy, D; Stefanovski, D; Salber, R; Sweeney, R W

2017-11-01

Calculation of desired whole blood transfusion volume relies on an estimate of an animal's circulating blood volume, generally accepted to be 0.08 L/kg or 8% of the animal's body weight in kilograms. To use packed cell volume before and after whole blood transfusion to evaluate the accuracy of a commonly used equation to predict packed cell volume after transfusion in small ruminants and South American camelids; to determine the nature and frequency of adverse transfusion reactions in small ruminants and camelids after whole blood transfusion. Fifty-eight small ruminants and 22 alpacas that received whole blood transfusions for anemia. Retrospective case series; medical record review for small ruminants and camelids that received whole blood transfusions during hospitalization. Mean volume of distribution of blood as a fraction of body weight in sheep (0.075 L/kg, 7.5% BW) and goats (0.076 L/kg, 7.6% BW) differed significantly (P blood volume (volume of distribution of blood) is adequate for calculation of transfusion volumes; however, use of the species-specific circulating blood volume can improve calculation of transfusion volume to predict and achieve desired packed cell volume. The incidence of transfusion reactions in small ruminants and camelids is low. Copyright © 2017 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

Factors affecting the development of in vitro fertilization in camelids

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Trasorras VL

2016-12-01

Full Text Available In any program of in vitro embryo production, the ultimate goal is to develop high quality embryos being able to get a normal pregnancy and finally resulting in the birth of a healthy offspring, goal not reach yet in camelids. The application of assisted reproductive techniques, such as in vitro fertilization and subsequent in vitro embryo culture, can extend the knowledge of early embryonic development and make possible the increase of the population of genetically superior animals.

Analysis of mitochondrial DNA in Bolivian llama, alpaca and vicuna populations: a contribution to the phylogeny of the South American camelids.

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Barreta, J; Gutiérrez-Gil, B; Iñiguez, V; Saavedra, V; Chiri, R; Latorre, E; Arranz, J J

2013-04-01

The objectives of this work were to assess the mtDNA diversity of Bolivian South American camelid (SAC) populations and to shed light on the evolutionary relationships between the Bolivian camelids and other populations of SACs. We have analysed two different mtDNA regions: the complete coding region of the MT-CYB gene and 513 bp of the D-loop region. The populations sampled included Bolivian llamas, alpacas and vicunas, and Chilean guanacos. High levels of genetic diversity were observed in the studied populations. In general, MT-CYB was more variable than D-loop. On a species level, the vicunas showed the lowest genetic variability, followed by the guanacos, alpacas and llamas. Phylogenetic analyses performed by including additional available mtDNA sequences from the studied species confirmed the existence of the two monophyletic clades previously described by other authors for guanacos (G) and vicunas (V). Significant levels of mtDNA hybridization were found in the domestic species. Our sequence analyses revealed significant sequence divergence within clade G, and some of the Bolivian llamas grouped with the majority of the southern guanacos. This finding supports the existence of more than the one llama domestication centre in South America previously suggested on the basis of archaeozoological evidence. Additionally, analysis of D-loop sequences revealed two new matrilineal lineages that are distinct from the previously reported G and V clades. The results presented here represent the first report on the population structure and genetic variability of Bolivian camelids and may help to elucidate the complex and dynamic domestication process of SAC populations. © 2012 The Authors, Animal Genetics © 2012 Stichting International Foundation for Animal Genetics.

Camelid immunoglobulins and nanobody technology.

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Muyldermans, S; Baral, T N; Retamozzo, V Cortez; De Baetselier, P; De Genst, E; Kinne, J; Leonhardt, H; Magez, S; Nguyen, V K; Revets, H; Rothbauer, U; Stijlemans, B; Tillib, S; Wernery, U; Wyns, L; Hassanzadeh-Ghassabeh, Gh; Saerens, D

2009-03-15

It is well established that all camelids have unique antibodies circulating in their blood. Unlike antibodies from other species, these special antibodies are devoid of light chains and are composed of a heavy-chain homodimer. These so-called heavy-chain antibodies (HCAbs) are expressed after a V-D-J rearrangement and require dedicated constant gamma-genes. An immune response is raised in these so-called heavy-chain antibodies following classical immunization protocols. These HCAbs are easily purified from serum, and the antigen-binding fragment interacts with parts of the target that are less antigenic to conventional antibodies. Since the antigen-binding site of the dromedary HCAb is comprised in one single domain, referred to as variable domain of heavy chain of HCAb (VHH) or nanobody (Nb), we designed a strategy to clone the Nb repertoire of an immunized dromedary and to select the Nbs with specificity for our target antigens. The monoclonal Nbs are well produced in bacteria, are very stable and highly soluble, and bind their cognate antigen with high affinity and specificity. We have successfully developed recombinant Nbs for research purposes, as probe in biosensors, to diagnose infections, and to treat diseases like cancer or trypanosomosis.

Pastoralism in northern Peru during pre-Hispanic times: insights from the Mochica Period (100-800 AD) based on stable isotopic analysis of domestic camelids.

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Dufour, Elise; Goepfert, Nicolas; Gutiérrez Léon, Belkys; Chauchat, Claude; Jordán, Régulo Franco; Vásquez Sánchez, Segundo

2014-01-01

Llama (Lama glama) and alpaca (Vicugna pacos) are the only large domesticated animals indigenous to the Americas. Pastoralism occupies a fundamental economic, social and religious role in Andean life. Today, camelid livestock are confined to the ecozone of the puna (above 3,500 masl), while their presence on the Pacific coast during pre-Hispanic times is attested by archaeological skeletal remains. This study aims to document herding practices on the northern Peruvian coast during the Early Intermediate Period (200 BC-600 AD) by gaining insights into diet, location of breeding and mobility of archaeological camelids from the funerary and ritual contexts of two Mochica sites, Uhle Platform in Huacas de Moche and El Brujo. The three first early years and the long-term life histories of the animals were documented by the combined bulk analysis of bone collagen (δ(13)C col and δ(15)N col) and bone structural carbonate (δ(13)C bone and δ(18)O bone) and the serial analysis of structural carbonate of molar tooth enamel (δ(13)C enamel and δ(18)O enamel). Mochica camelids were bred in the low and/or middle valleys, unlike their modern counterparts, who are restricted to highland puna C3 pastures. Archaeological camelids had diverse and complex life histories, usually with substantial maize foddering. An ontogenetic switch in diet and possible residential mobility during the course of life were identified for some specimens. Although the inference of geographic origin from δ(18)O bone and δ(18)O enamel values was limited because of the lack of understanding of the influence of environmental and biological factors, tooth enamel analysis has great potential for exploring camelid herding practices and Andean pastoralism. Our study suggested that Mochica herders adapted their practices to the difficult lowland environment and that herding practices were varied and not restricted to breeding at higher altitudes. The role of maize in different aspects of the economic life

Pastoralism in northern Peru during pre-Hispanic times: insights from the Mochica Period (100-800 AD based on stable isotopic analysis of domestic camelids.

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Elise Dufour

Full Text Available Llama (Lama glama and alpaca (Vicugna pacos are the only large domesticated animals indigenous to the Americas. Pastoralism occupies a fundamental economic, social and religious role in Andean life. Today, camelid livestock are confined to the ecozone of the puna (above 3,500 masl, while their presence on the Pacific coast during pre-Hispanic times is attested by archaeological skeletal remains. This study aims to document herding practices on the northern Peruvian coast during the Early Intermediate Period (200 BC-600 AD by gaining insights into diet, location of breeding and mobility of archaeological camelids from the funerary and ritual contexts of two Mochica sites, Uhle Platform in Huacas de Moche and El Brujo. The three first early years and the long-term life histories of the animals were documented by the combined bulk analysis of bone collagen (δ(13C col and δ(15N col and bone structural carbonate (δ(13C bone and δ(18O bone and the serial analysis of structural carbonate of molar tooth enamel (δ(13C enamel and δ(18O enamel. Mochica camelids were bred in the low and/or middle valleys, unlike their modern counterparts, who are restricted to highland puna C3 pastures. Archaeological camelids had diverse and complex life histories, usually with substantial maize foddering. An ontogenetic switch in diet and possible residential mobility during the course of life were identified for some specimens. Although the inference of geographic origin from δ(18O bone and δ(18O enamel values was limited because of the lack of understanding of the influence of environmental and biological factors, tooth enamel analysis has great potential for exploring camelid herding practices and Andean pastoralism. Our study suggested that Mochica herders adapted their practices to the difficult lowland environment and that herding practices were varied and not restricted to breeding at higher altitudes. The role of maize in different aspects of the economic

Pastoralism in Northern Peru during Pre-Hispanic Times: Insights from the Mochica Period (100–800 AD) Based on Stable Isotopic Analysis of Domestic Camelids

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Dufour, Elise; Goepfert, Nicolas; Gutiérrez Léon, Belkys; Chauchat, Claude; Franco Jordán, Régulo; Sánchez, Segundo Vásquez

2014-01-01

Llama (Lama glama) and alpaca (Vicugna pacos) are the only large domesticated animals indigenous to the Americas. Pastoralism occupies a fundamental economic, social and religious role in Andean life. Today, camelid livestock are confined to the ecozone of the puna (above 3,500 masl), while their presence on the Pacific coast during pre-Hispanic times is attested by archaeological skeletal remains. This study aims to document herding practices on the northern Peruvian coast during the Early Intermediate Period (200 BC-600 AD) by gaining insights into diet, location of breeding and mobility of archaeological camelids from the funerary and ritual contexts of two Mochica sites, Uhle Platform in Huacas de Moche and El Brujo. The three first early years and the long-term life histories of the animals were documented by the combined bulk analysis of bone collagen (δ13Ccol and δ15Ncol) and bone structural carbonate (δ13Cbone and δ18Obone) and the serial analysis of structural carbonate of molar tooth enamel (δ13Cenamel and δ18Oenamel). Mochica camelids were bred in the low and/or middle valleys, unlike their modern counterparts, who are restricted to highland puna C3 pastures. Archaeological camelids had diverse and complex life histories, usually with substantial maize foddering. An ontogenetic switch in diet and possible residential mobility during the course of life were identified for some specimens. Although the inference of geographic origin from δ18Obone and δ18Oenamel values was limited because of the lack of understanding of the influence of environmental and biological factors, tooth enamel analysis has great potential for exploring camelid herding practices and Andean pastoralism. Our study suggested that Mochica herders adapted their practices to the difficult lowland environment and that herding practices were varied and not restricted to breeding at higher altitudes. The role of maize in different aspects of the economic life of the Mochicas is also

Polydactyly suggesting local husbandry of Pre-Columbian camelids: A case from Castillo de Huarmey archaeological site, northern coast of Peru.

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Tomczyk, Weronika; Giersz, Miłosz

2017-03-01

Three camelid metapodials with polydactyly (additional digits) were found at the Wari culture archaeological site (dated to the Middle Horizon) of Castillo de Huarmey. The anomalous bones were excavated among numerous remains, and presumably represent animals that were sacrificed within the principal mortuary mausoleum. The bones derive from at least two individuals. The etiology of the deformities remains unknown, but the most probable causes include low genetic diversity in the herd or unintended effect of selective breeding. The likelihood of impaired locomotion suggests birth and rearing within the site vicinity. The animals were juvenile, apparently killed around the age of sexual maturity, when they would have attained maximum body mass. Purposeful funerary proceedings with deformed animals suggest (at least) a locally developed camelid husbandry. Copyright © 2016 Elsevier Inc. All rights reserved.

The new world disorder.

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Checa, Nicolas; Maguire, John; Barney, Jonathan

2003-08-01

On January 1, 1995, representatives from 76 countries signed the World Trade Organization charter, which for years had been part of a temporary trade agreement. The WTO's emergence as a fully empowered supranational body seemed to reflect the triumph of what the first President Bush had described as the "new world order." That order was based on two assumptions: that a healthy economy and a sound financial system make for political stability, and that countries in business together do not fight each other. The number one priority of U.S. foreign policy was thus to encourage the former Communist countries of Europe and the developing nations in Latin America, Asia, and Africa to adopt business-friendly policies. Private capital would flow from the developed world into these countries, creating economic growth. It sounded too good to be true, and so it proved. The new world order of Bush père and his successor, Bill Clinton, has been replaced by the new world disorder of Bush fils. Under the second Bush's administration, the economic and political rationale-behind the Washington consensus of the 1990s has unraveled, forcing a radical change in our perceptions of which countries are safe for business. Negotiating this new environment will require companies to more rigorously evaluate political events and more carefully assess the links between political, economic, and financial risk factors. They'll need to be more selective about which markets to enter, and they'll need to think differently about how to position themselves in those markets. The geopolitical events of the past year, the Bush administration's global war on terror, as well as ongoing convulsions in traditional political and economic relationships must be understood and managed by corporate leaders worldwide. With careful analysis, business leaders can increase their companies' visibility and better respond to the uncertainties of the new world disorder.

A Rational Engineering Strategy for Designing Protein A-Binding Camelid Single-Domain Antibodies

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Henry, Kevin A.; Sulea, Traian; van Faassen, Henk; Hussack, Greg; Purisima, Enrico O.; MacKenzie, C. Roger; Arbabi-Ghahroudi, Mehdi

2016-01-01

Staphylococcal protein A (SpA) and streptococcal protein G (SpG) affinity chromatography are the gold standards for purifying monoclonal antibodies (mAbs) in therapeutic applications. However, camelid VHH single-domain Abs (sdAbs or VHHs) are not bound by SpG and only sporadically bound by SpA. Currently, VHHs require affinity tag-based purification, which limits their therapeutic potential and adds considerable complexity and cost to their production. Here we describe a simple and rapid mutagenesis-based approach designed to confer SpA binding upon a priori non-SpA-binding VHHs. We show that SpA binding of VHHs is determined primarily by the same set of residues as in human mAbs, albeit with an unexpected degree of tolerance to substitutions at certain core and non-core positions and some limited dependence on at least one residue outside the SpA interface, and that SpA binding could be successfully introduced into five VHHs against three different targets with no adverse effects on expression yield or antigen binding. Next-generation sequencing of llama, alpaca and dromedary VHH repertoires suggested that species differences in SpA binding may result from frequency variation in specific deleterious polymorphisms, especially Ile57. Thus, the SpA binding phenotype of camelid VHHs can be easily modulated to take advantage of tag-less purification techniques, although the frequency with which this is required may depend on the source species. PMID:27631624

Inhibition of the Myotoxicity Induced by Bothrops jararacussu Venom and Isolated Phospholipases A2 by Specific Camelid Single-Domain Antibody Fragments.

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Nidiane D R Prado

Full Text Available Antivenoms, produced using animal hyperimmune plasma, remains the standard therapy for snakebites. Although effective against systemic damages, conventional antivenoms have limited efficacy against local tissue damage. Additionally, the hypersensitivity reactions, often elicited by antivenoms, the high costs for animal maintenance, the difficulty of producing homogeneous lots, and the instability of biological products instigate the search for innovative products for antivenom therapy. In this study, camelid antibody fragments (VHH with specificity to Bothropstoxin I and II (BthTX-I and BthTX-II, two myotoxic phospholipases from Bothrops jararacussu venom, were selected from an immune VHH phage display library. After biopanning, 28 and 6 clones recognized BthTX-I and BthTX-II by ELISA, respectively. Complementarity determining regions (CDRs and immunoglobulin frameworks (FRs of 13 VHH-deduced amino acid sequences were identified, as well as the camelid hallmark amino acid substitutions in FR2. Three VHH clones (KF498607, KF498608, and KC329718 were capable of recognizing BthTX-I by Western blot and showed affinity constants in the nanomolar range against both toxins. VHHs inhibited the BthTX-II phospholipase A2 activity, and when tested for cross-reactivity, presented specificity to the Bothrops genus in ELISA. Furthermore, two clones (KC329718 and KF498607 neutralized the myotoxic effects induced by B. jararacussu venom, BthTX-I, BthTX-II, and by a myotoxin from Bothrops brazili venom (MTX-I in mice. Molecular docking revealed that VHH CDRs are expected to bind the C-terminal of both toxins, essential for myotoxic activity, and to epitopes in the BthTX-II enzymatic cleft. Identified VHHs could be a biotechnological tool to improve the treatment for snake envenomation, an important and neglected world public health problem.

New frontiers for tomorrow's world

International Nuclear Information System (INIS)

Kassler, P.

1994-01-01

The conference paper deals with new frontiers and barricades in the global economic development and their influence on fuel consumption and energy source development. Topics discussed are incremental energy supply - new frontiers, world car population - new frontiers, OPEC crude production capacity vs call on OPEC, incremental world oil demand by region 1992-2000, oil resource cost curve, progress in seismic 1983-1991, Troll picture, cost reduction in renewables, sustained growth scenario, nuclear electricity capacity - France, OECD road transport fuels - barricades, and energy taxation. 18 figs

Camelid genomes reveal evolution and adaptation to desert environments.

Science.gov (United States)

Wu, Huiguang; Guang, Xuanmin; Al-Fageeh, Mohamed B; Cao, Junwei; Pan, Shengkai; Zhou, Huanmin; Zhang, Li; Abutarboush, Mohammed H; Xing, Yanping; Xie, Zhiyuan; Alshanqeeti, Ali S; Zhang, Yanru; Yao, Qiulin; Al-Shomrani, Badr M; Zhang, Dong; Li, Jiang; Manee, Manee M; Yang, Zili; Yang, Linfeng; Liu, Yiyi; Zhang, Jilin; Altammami, Musaad A; Wang, Shenyuan; Yu, Lili; Zhang, Wenbin; Liu, Sanyang; Ba, La; Liu, Chunxia; Yang, Xukui; Meng, Fanhua; Wang, Shaowei; Li, Lu; Li, Erli; Li, Xueqiong; Wu, Kaifeng; Zhang, Shu; Wang, Junyi; Yin, Ye; Yang, Huanming; Al-Swailem, Abdulaziz M; Wang, Jun

2014-10-21

Bactrian camel (Camelus bactrianus), dromedary (Camelus dromedarius) and alpaca (Vicugna pacos) are economically important livestock. Although the Bactrian camel and dromedary are large, typically arid-desert-adapted mammals, alpacas are adapted to plateaus. Here we present high-quality genome sequences of these three species. Our analysis reveals the demographic history of these species since the Tortonian Stage of the Miocene and uncovers a striking correlation between large fluctuations in population size and geological time boundaries. Comparative genomic analysis reveals complex features related to desert adaptations, including fat and water metabolism, stress responses to heat, aridity, intense ultraviolet radiation and choking dust. Transcriptomic analysis of Bactrian camels further reveals unique osmoregulation, osmoprotection and compensatory mechanisms for water reservation underpinned by high blood glucose levels. We hypothesize that these physiological mechanisms represent kidney evolutionary adaptations to the desert environment. This study advances our understanding of camelid evolution and the adaptation of camels to arid-desert environments.

Novel camelid antibody fragments targeting recombinant nucleoprotein of Araucaria hantavirus: a prototype for an early diagnosis of Hantavirus Pulmonary Syndrome.

Directory of Open Access Journals (Sweden)

Soraya S Pereira

Full Text Available In addition to conventional antibodies, camelids produce immunoglobulins G composed exclusively of heavy chains in which the antigen binding site is formed only by single domains called VHH. Their particular characteristics make VHHs interesting tools for drug-delivery, passive immunotherapy and high-throughput diagnosis. Hantaviruses are rodent-borne viruses of the Bunyaviridae family. Two clinical forms of the infection are known. Hemorrhagic Fever with Renal Syndrome (HFRS is present in the Old World, while Hantavirus Pulmonary Syndrome (HPS is found on the American continent. There is no specific treatment for HPS and its diagnosis is carried out by molecular or serological techniques, using mainly monoclonal antibodies or hantavirus nucleoprotein (N to detect IgM and IgG in patient serum. This study proposes the use of camelid VHHs to develop alternative methods for diagnosing and confirming HPS. Phage display technology was employed to obtain VHHs. After immunizing one Lama glama against the recombinant N protein (prNΔ₈₅ of a Brazilian hantavirus strain, VHH regions were isolated to construct an immune library. VHHs were displayed fused to the M13KO7 phage coat protein III and the selection steps were performed on immobilized prNΔ₈₅. After selection, eighty clones recognized specifically the N protein. These were sequenced, grouped based mainly on the CDRs, and five clones were analyzed by western blot (WB, surface plasmon resonance (SPR device, and ELISA. Besides the ability to recognize prNΔ85 by WB, all selected clones showed affinity constants in the nanomolar range. Additionaly, the clone KC329705 is able to detect prNΔ₈₅ in solution, as well as the native viral antigen. Findings support the hypothesis that selected VHHs could be a powerful tool in the development of rapid and accurate HPS diagnostic assays, which are essential to provide supportive care to patients and reduce the high mortality rate associated with

[South American camelids in Switzerland. II. Reference values for blood parameters].

Science.gov (United States)

Hengrave Burri, I; Tschudi, P; Martig, J; Liesegang, A; Meylan, M

2005-08-01

In order to establish reference values for blood parameters of South American camelids in Switzerland, 273 blood samples were collected from 141 llamas and 132 alpacas. These animals were classified in three categories (young animals blood cell count, white blood cell count, electrolytes, metabolites and enzymes). Significant differences between llamas and alpacas were evident for 26 parameters. This study also showed that differences between young animals, females and males must be taken into consideration. A comparison of blood values with the results of fecal analysis for parasite eggs showed that an infestation with Dicrocoelium dendriticum was associated with elevated activity of two liver enzymes (GLDH and gamma-GT) in the serum. In contrast, no differences were found in the results of blood analyses between animals shedding eggs of gastrointestinal strongyles or not.

New Worlds, New Horizons in Astronomy and Astrophysics

National Research Council Canada - National Science Library

2010-01-01

.... Based on a broad and comprehensive survey of scientific opportunities, infrastructure, and organization in a national and international context, New Worlds, New Horizons in Astronomy and Astrophysic...

Coming to America: multiple origins of New World geckos.

Science.gov (United States)

Gamble, T; Bauer, A M; Colli, G R; Greenbaum, E; Jackman, T R; Vitt, L J; Simons, A M

2011-02-01

Geckos in the Western Hemisphere provide an excellent model to study faunal assembly at a continental scale. We generated a time-calibrated phylogeny, including exemplars of all New World gecko genera, to produce a biogeographical scenario for the New World geckos. Patterns of New World gecko origins are consistent with almost every biogeographical scenario utilized by a terrestrial vertebrate with different New World lineages showing evidence of vicariance, dispersal via temporary land bridge, overseas dispersal or anthropogenic introductions. We also recovered a strong relationship between clade age and species diversity, with older New World lineages having more species than more recently arrived lineages. Our data provide the first phylogenetic hypothesis for all New World geckos and highlight the intricate origins and ongoing organization of continental faunas. The phylogenetic and biogeographical hypotheses presented here provide an historical framework to further pursue research on the diversification and assembly of the New World herpetofauna. © 2010 The Authors. Journal of Evolutionary Biology © 2010 European Society For Evolutionary Biology.

Effect of the Camelid's Seminal Plasma Ovulation-Inducing Factor/β-NGF: A Kisspeptin Target Hypothesis.

Science.gov (United States)

El Allali, Khalid; El Bousmaki, Najlae; Ainani, Hassan; Simonneaux, Valérie

2017-01-01

Female mammals are classified into spontaneous and induced ovulators based on the mechanism eliciting ovulation. Ovulation in spontaneous species (e.g., human, sheep, cattle, horse, pigs, and most rodents) occurs at regular intervals and depends upon the circulating estradiol. However, in induced ovulators (e.g., rabbits, ferrets, cats, and camelids), ovulation is associated with coitus. In the later, various factors have been proposed to trigger ovulation, including auditory, visual, olfactory, and mechanic stimuli. However, other studies have identified a biochemical component in the semen of induced ovulators responsible for the induction of ovulation and named accordingly ovulation-inducing factor (OIF). In camelids, intramuscular or intrauterine administration of seminal plasma (SP) was shown to induce the preovulatory luteinizing hormone (LH) surge followed by ovulation and subsequent formation of corpus luteum. Recently, this OIF has been identified from SP as a neurotrophin, the β subunit of nerve growth factor (β-NGF). β-NGF is well known as promoting neuron survival and growth, but in this case, it appears to induce ovulation through an endocrine mode of action. Indeed, β-NGF may be absorbed through the endometrium to be conveyed, via the blood stream, to the central structures regulating the LH preovulatory surge. In this review, we provide a summary of the most relevant results obtained in the field, and we propose a working hypothesis for the central action of β-NGF based on our recent demonstration of the presence of neurons expressing kisspeptin, a potent stimulator of GnRH/LH, in the camel hypothalamus.

Lamanema chavezi (Nematoda: Molineidae): epidemiological data of the infection in South American camelids of Northwest Argentina.

Science.gov (United States)

Cafrune, M M; Marín, R E; Rigalt, F A; Romero, S R; Aguirre, D H

2009-12-23

Faecal samples from llamas (n=708), vicuñas (n=171) and guanacos (n=4) were obtained between December 2004 and May 2009 in three Provinces of Northwest Argentina (Jujuy, Salta and Catamarca) to know the distribution, prevalence and intensity of Lamanema chavezi infection in these South American camelid species (SACs). Faeces were examined by a sedimentation-flotation technique using a Cl(2)Zn+ClNa solution (specific gravity=1.59). Eggs of L. chavezi occurred in 30.3% of 89 llama herds and in 18.5% of 708 llamas sampled with a mean intensity of 271.8 eggs/g (EPG) of faeces (range 20-2120). The highest values for all parameters of the infection were registered in llamas from Catamarca Province. Significant differences (P<0.001, Fisher's exact test) were detected only for the lower prevalence in llamas from Jujuy respect to those from the other two Provinces. The overall individual prevalence of L. chavezi in llamas was lower than in reports from adult domestic camelids of neighbour countries while mean intensity was higher. The individual prevalence of L. chavezi in guanacos was 75.0%, with a mean intensity of 66.0 EPG (range 40-120) while no vicuñas were detected as infected. Most of infected SACs were located at the phytogeographical region of Andean Patagonic Domain with a dispersion ranging between 22 degrees 10' and 26 degrees 40' South latitude.

New frontiers for tomorrow`s world

Energy Technology Data Exchange (ETDEWEB)

Kassler, P [Shell International Petroleum Co. Ltd., London (United Kingdom)

1994-12-31

The conference paper deals with new frontiers and barricades in the global economic development and their influence on fuel consumption and energy source development. Topics discussed are incremental energy supply - new frontiers, world car population - new frontiers, OPEC crude production capacity vs call on OPEC, incremental world oil demand by region 1992-2000, oil resource cost curve, progress in seismic 1983-1991, Troll picture, cost reduction in renewables, sustained growth scenario, nuclear electricity capacity - France, OECD road transport fuels - barricades, and energy taxation. 18 figs.

A NEW THINKING FOR A NEW WORLD. REPRESENTATIONS FROM ECONOMY

Directory of Open Access Journals (Sweden)

Negucioiu Aurel

2011-07-01

Full Text Available An incursion, even a succinct one, incomplete, in the universal history, in the world economic history and not in the least in the real world gives more and more credit to the idea according to which the movement is the main form of existence- working and evolution- of the society, economy, and of all the structures they are made of. Its "force motrice", its internal cause is represented, in our opinion, the unity and interaction of opposites. The changes, the transformations taking place in society and in its economy have direct or indirect authors the human beings who, using their minds, "leaven bread" and express at the beginning through thinking, the objectives that are going to complete or lessen reality. The positive changes and transformations that the people operate renew the world. For more than half of a century, the humankind has been in a vast and very complex process of transformation, changes with innovative character. In other words, a process of building a new world. Hence, the need to create a new thinking. "A new thinking for a new world" Making a halt in the field of economy -theory, science and practice - we are trying to bring to attention to those interested a few considerations concerning the truth value of some paradigms in the theoretical circuit, including their degree of rationality or irrationality.

Morphofunctional structure of the lingual papillae in three species of South American Camelids: Alpaca, guanaco, and llama.

Science.gov (United States)

Erdoğan, Serkan; Villar Arias, Silvia; Pérez, William

2016-02-01

The aim of this study was to compare the anatomical and functional characteristics of the lingual papilla among the Camelidae. For this purpose, tongues of alpaca, guanaco, and llama were used. Numerous long and thin filiform papillae were located in the median groove and none were detected on the rest of the dorsal surface of the lingual apex in alpaca. Secondary papillae originated from the base of some filiform papillae on the ventral surface of alpaca tongue. The bases of some filiform papillae of the lateral surface of the lingual apex were inserted into conspicuous grooves in guanaco and tips of filiform papillae on the dorsal surface of the lingual body were ended by bifurcated apex. On the dorsal surface of the lingual apex of llama, there were no filiform papillae but there were numerous filiform papillae on both the lateral margins of the ventral surface of the lingual apex. Fungiform papillae were distributed randomly on dorsal lingual surface and ventral margins of the tongues of all camelid species. Lenticular papillae were located on the lingual torus and varied in size and topographical distribution for each species. Circumvallate papillae had irregular surfaces in llama and alpaca, and smooth surface in guanaco. In conclusion, llama and alpaca tongues were more similar to each other, and tongues of all camelid species displayed more similarities to those of Bactrian and dromedary camels in comparison with other herbivores and ruminants. © 2015 Wiley Periodicals, Inc.

Semen preservation and artificial insemination in domesticated South American camelids.

Science.gov (United States)

Bravo, P Walter; Alarcon, V; Baca, L; Cuba, Y; Ordoñez, C; Salinas, J; Tito, F

2013-01-10

Semen preservation and artificial insemination in South American camelids are reviewed giving emphasis to work done in Peru and by the authors. Reports on semen evaluation and the preservation process indicate that semen of alpacas and llamas can be manipulated by making it liquid first. Collagenase appears to be the best enzyme to eliminate viscosity. Tris buffer solution maintains a higher motility than egg-yolk citrate, phosphate buffered saline (PBS), Triladyl, and Merck-I extenders. Cooling of semen took 1h after collected, and equilibrated with 7% glycerol presented a better motility and spermatozoa survival at 1, 7, 15 and 30days after being slowly frozen in 0.25mL plastic straws. Trials of artificial insemination with freshly diluted semen and frozen-thawed semen are encouraging and needs to be tested extensively under field conditions. Recently, fertility rates varied from 3 to 67%. Semen preservation and most important, artificial insemination appear to be a reality, and could be used to improve the genetic quality of alpacas and llamas. Copyright © 2012 Elsevier B.V. All rights reserved.

Generalized Tuberculosis in Llamas (Lama glama) Due to Mycobacterium microti

Science.gov (United States)

Oevermann, A.; Pfyffer, G. E.; Zanolari, P.; Meylan, M.; Robert, N.

2004-01-01

Necropsy of two llamas revealed numerous caseous nodules containing abundant acid-fast bacilli (AFB) in various organs. The AFB were identified by spoligotyping as Mycobacterium microti, vole type. Infection caused by M. microti should be considered in the differential diagnosis of debilitating diseases in New World camelids. PMID:15071059

Searching for the New World Monetary Standard

Directory of Open Access Journals (Sweden)

Ishkhanov Aleksandr Vladimirovich

2014-11-01

Full Text Available In the article the influence of the existing world currency system on the international financial relations is considered, the retrospective analysis of the existing four currency systems is carried out. The change of a world currency order is justified. The concept of the new international currency standard based on division of functions of money between separate financial instruments of one currency is offered. The functional communications between financial instruments are revealed. The comparison of function of money and independent tools of new world currency is carried out, it is supposed that tools are actually completely capable to carry out all functions of money. Therefore, the new international currency standard is based on division of these functions between separate tools and can be defined as polytool. The general function chart of the polytool world currency standard including their functional connections between reserve tool, reverse tool and credit as well as their characteristics which should determine the activity of world reserve system. Prerequisites of replacement of the Jamaican currency system by the alternative are proved; the most perspective way of transition to the polytool standard is revealed; the additional functions of the polytool standard are designated – stimulation of issuers of the leading world currencies to refuse harmful policy of competitive devaluation, stimulation of integration of the countries and creation of collective currencies (currency zones and associations that will significantly increase financial stability of world economy.

Get Involved in Planetary Discoveries through New Worlds, New Discoveries

Science.gov (United States)

Shupla, Christine; Shipp, S. S.; Halligan, E.; Dalton, H.; Boonstra, D.; Buxner, S.; SMD Planetary Forum, NASA

2013-01-01

"New Worlds, New Discoveries" is a synthesis of NASA’s 50-year exploration history which provides an integrated picture of our new understanding of our solar system. As NASA spacecraft head to and arrive at key locations in our solar system, "New Worlds, New Discoveries" provides an integrated picture of our new understanding of the solar system to educators and the general public! The site combines the amazing discoveries of past NASA planetary missions with the most recent findings of ongoing missions, and connects them to the related planetary science topics. "New Worlds, New Discoveries," which includes the "Year of the Solar System" and the ongoing celebration of the "50 Years of Exploration," includes 20 topics that share thematic solar system educational resources and activities, tied to the national science standards. This online site and ongoing event offers numerous opportunities for the science community - including researchers and education and public outreach professionals - to raise awareness, build excitement, and make connections with educators, students, and the public about planetary science. Visitors to the site will find valuable hands-on science activities, resources and educational materials, as well as the latest news, to engage audiences in planetary science topics and their related mission discoveries. The topics are tied to the big questions of planetary science: how did the Sun’s family of planets and bodies originate and how have they evolved? How did life begin and evolve on Earth, and has it evolved elsewhere in our solar system? Scientists and educators are encouraged to get involved either directly or by sharing "New Worlds, New Discoveries" and its resources with educators, by conducting presentations and events, sharing their resources and events to add to the site, and adding their own public events to the site’s event calendar! Visit to find quality resources and ideas. Connect with educators, students and the public to

The 'New' World Literature: A Review Essay

Directory of Open Access Journals (Sweden)

Russell McDougall

2014-05-01

Full Text Available Works discussed: Theo D'haen, The Routledge Concise History of World Literature (Routledge, 2011; Theo D'haen, David Damrosch & Djelal Kadir, eds. The Routledge Companion to World Literature (Routledge, 2011; Theo D'haen, Cesar Dominguez & Mads Rosendahl Thomsen eds., World Literature: A Reader (Routledge, 2012; Elke Sturm-Trigonakis, Comparative Cultural Studies and the New Weltliteratur (Purdue University Press, 2013; Emily Apter, Against World Literature: On the Politics of Untranslatability (Verso, 2013; Robert Dixon and Bridget Rooney, Scenes of Reading. Is Australian Literature a World Literature? (Australian Scholarly Publishing, 2013; David Damrosch. ed. World Literature in Theory (Wiley-Blackwell, 2014

World nuclear performance report 2016. A new study by World Nuclear Association

Energy Technology Data Exchange (ETDEWEB)

Cobb, Jonathan [World Nuclear Association, London (United Kingdom)

2016-08-15

A larger number of nuclear power units are under construction than at any other time in the last 25 years, and with another ten new reactors coming online 2015 demonstrated improving new build performance all round. The existing global fleet, totally 439 by year-end, generated roughly 10 % of the world's electricity, making up around one-third of the world's low-carbon electricity supply. Nevertheless, there are challenges ahead for the global nuclear industry. The World Nuclear Association's vision for the future global electricity system consists of a diverse mix of low-carbon technologies - where renewables, nuclear and a fossil fuels work together in harmony to ensure a reliable, affordable and clean energy supply.

World nuclear performance report 2016. A new study by World Nuclear Association

International Nuclear Information System (INIS)

Cobb, Jonathan

2016-01-01

A larger number of nuclear power units are under construction than at any other time in the last 25 years, and with another ten new reactors coming online 2015 demonstrated improving new build performance all round. The existing global fleet, totally 439 by year-end, generated roughly 10 % of the world's electricity, making up around one-third of the world's low-carbon electricity supply. Nevertheless, there are challenges ahead for the global nuclear industry. The World Nuclear Association's vision for the future global electricity system consists of a diverse mix of low-carbon technologies - where renewables, nuclear and a fossil fuels work together in harmony to ensure a reliable, affordable and clean energy supply.

Efficacy of anthelmintics on South American camelid (llama and alpaca) farms in Georgia.

Science.gov (United States)

Gillespie, Rose-Ann M; Williamson, Lisa H; Terrill, Thomas H; Kaplan, Ray M

2010-08-27

The number of South American camelid (SAC; llama and alpaca) farms is growing in the southeastern United States, and infection with gastrointestinal nematodes (GIN) is a major health concern in this region. There is widespread resistance to anthelmintic remedies in small ruminants (sheep and goats), but a paucity of information on llamas and alpacas. Anthelmintic resistance was evaluated on three SAC farms (two llama; one alpaca) in Georgia in the southern United States using fecal egg count reduction (FECR) tests. For each farm, animals were randomly assigned to 1 of 5 treatment groups based on initial fecal egg count (FEC) and number of animals available (2-5 groups, n=9-11 per treatment). Ivermectin (IVM, subcutaneous injection; 0.3mg/kg body weight (BW)) and a control group were tested on an alpaca farm, and fenbendazole (FBZ, oral; 10mg/kg BW; two farms), moxidectin (MOX oral; 0.2mg/kg BW; two farms), and levamisole (LEV, oral; 8 mg/kg BW; one farm) were added for the llama farms. Anthelmintic efficacy was determined by comparing FEC of treatment and control animals 14 days post-treatment, with resistance evaluated using the World Association for the Advancement of Veterinary Parasitology (WAAVP) guidelines. Based upon these guidelines, there was GIN resistance to IVM in both llamas and alpacas in Georgia and to FBZ on both llama farms where this drug was tested. There was MOX resistance on one llama farm using the FECR test, while there was no resistance to LEV detected in this study. These data demonstrate a serious emerging problem in the United States of llama and alpaca GIN resistant to drugs from two of the three major anthelmintic classes. (c) 2010 Elsevier B.V. All rights reserved.

New World Pouzozlia and Boehmeria (Urticaceae)

DEFF Research Database (Denmark)

Wilmot-Dear, Christine Melanie; Friis, Ib

2011-01-01

The paper supplements a revision of the New World species of Boehmeria and Pouzozia published by the authors in 1996. Pouzolzia amambaiensis sp. nov. is described from recent material from Paraguay near the border with Brazil and represents a new generic record for Paraguay. Also recorded...

Streptococcus equi subsp zooepidemicus pleuropneumonia and peritonitis in a dromedary camel (Camelus dromedarius) calf in North America.

Science.gov (United States)

Stoughton, William B; Gold, Jenifer

2015-08-01

A 12-week-old female dromedary camel (Camelus dromedarius) calf was evaluated because of acute (blood, peritoneal fluid, and pleural fluid samples indicated Streptococcus equi subsp zooepidemicus septicemia as the etiology for the polyserositis (ie, alpaca fever). Treatment with IV broad-spectrum antimicrobials, an NSAID, and pleural drainage was initiated. Clinical signs of pleuropneumonia, peritonitis, and systemic infection improved rapidly 24 hours after initiation of medical treatment. The calf was discharged from the hospital after 11 days, and antimicrobial treatment continued for 2 weeks after discharge. At follow-up approximately 4 weeks after hospital discharge (6 weeks after the initial examination), there were no clinical signs suggestive of relapse or any reported complications. S equi subsp zooepidemicus may cause polyserositis in Old World camelids (eg, dromedary camels) with signs similar to those seen in New World camelids (eg, alpaca and llama). The rapid response to medical treatment for the patient described suggested that S equi subsp zooepidemicus-induced polyserositis (alpaca fever) in dromedary camels may respond favorably to appropriate treatment. Reducing stress, reducing overcrowding, and separate housing of equids and camelids are suggested. Further studies are needed to better assess the epidemiology of alpaca fever in dromedary camels in North America.

Where the New World Is

DEFF Research Database (Denmark)

Bone, Martyn Richard

in weaving together southern literary studies and post-national American studies. Americanists of all kinds will learn a great deal from this important work." —Harilaos Stecopoulos, author of Reconstructing the World: Southern Fictions and U.S. Imperialisms, 1898–1976 "Martyn Bone's Where The New World...... earlier twentieth-century writing already had done so in ways traditional southern literary studies tended to ignore. Martyn Bone argues that this body of fiction has, over the course of some eighty years, challenged received readings and understandings of the U.S. South as a fixed place largely untouched......, and Laila Lalami. The book also seeks to resituate southern studies by drawing on theories of “scale” that originated in human geography. In this way, Bone also offers a new paradigm in which the U.S. South is thoroughly engaged with a range of other scales from the local to the global, making both...

Y-chromosome and mtDNA variation confirms independent domestications and directional hybridization in South American camelids.

Science.gov (United States)

Marín, J C; Romero, K; Rivera, R; Johnson, W E; González, B A

2017-10-01

Investigations of genetic diversity and domestication in South American camelids (SAC) have relied on autosomal microsatellite and maternally-inherited mitochondrial data. We present the first integrated analysis of domestic and wild SAC combining male and female sex-specific markers (male specific Y-chromosome and female-specific mtDNA sequence variation) to assess: (i) hypotheses about the origin of domestic camelids, (ii) directionality of introgression among domestic and/or wild taxa as evidence of hybridization and (iii) currently recognized subspecies patterns. Three male-specific Y-chromosome markers and control region sequences of mitochondrial DNA are studied here. Although no sequence variation was found in SRY and ZFY, there were seven variable sites in DBY generating five haplotypes on the Y-chromosome. The haplotype network showed clear separation between haplogroups of guanaco-llama and vicuña-alpaca, indicating two genetically distinct patrilineages with near absence of shared haplotypes between guanacos and vicuñas. Although we document some examples of directional hybridization, the patterns strongly support the hypothesis that llama (Lama glama) is derived from guanaco (Lama guanicoe) and the alpaca (Vicugna pacos) from vicuña (Vicugna vicugna). Within male guanacos we identified a haplogroup formed by three haplotypes with different geographical distributions, the northernmost of which (Peru and northern Chile) was also observed in llamas, supporting the commonly held hypothesis that llamas were domesticated from the northernmost populations of guanacos (L. g. cacilensis). Southern guanacos shared the other two haplotypes. A second haplogroup, consisting of two haplotypes, was mostly present in vicuñas and alpacas. However, Y-chromosome variation did not distinguish the two subspecies of vicuñas. © 2017 Stichting International Foundation for Animal Genetics.

Palynological analysis of camelid coprolites: seasonality in the use of the site Cerro Casa de Piedra 7 (Santa Cruz, Argentina)

Science.gov (United States)

Velázquez, Nadia Jimena; Burry, Lidia Susana; Fugassa, Martín Horacio; Civalero, María Teresa; Aschero, Carlos Alberto

2014-01-01

Palynological, palaeoparasitological and paleobotanical studies of coprolites found in archaeological sites from Perito Moreno National Park (47°57‧S72°05‧W) yielded information on diet, palaeoenvironment and health. These studies allowed adding evidence to the reconstruction of life history of the hunter-gatherers that inhabited Patagonia during the Holocene. We examined the season of the year when camelid Lama guanicoe coprolites (5400 ± 64 yr 14C BP to 9640 ± 190 yr 14C BP) were deposited at Cerro Casa de Piedra 7 (site CCP7). The study used palynological evidence and comparison with pollen spectra of modern feces collected during summer, fall, winter and spring of 2010. The dominant types were: pollen of Nothofagus, Empetrum rubrum, Asteraceae subfam. Asteroideae, Nassauvia, Caryophyllaceae and Poaceae; fern spores; remains of Eimeria macusaniensis; and plant remains of Poaceae, Festuca pallescens, Stipa speciosa, Armeria maritima, Gaultheria mucronata and E. rubrum. Pollen spectra of modern and fossil feces were used for multivariate analysis. Coprolites associated to fall and winter modern feces. These results and those obtained from pollen concentration values and the presence of pollen types indicators of seasonality, allowed the determination of summer, fall and winter coprolites. However, caution must be taken with the seasonality results of coprolites dated earlier than 9000 years BP since the environmental conditions differed from now. The site was probably a camelid shelter during the unfavorable seasons.

New Approaches to the World Food Problem

Science.gov (United States)

Brownell, L. E.

1970-01-01

Discusses some possible solutions to the problem of hunger and malnutrition in the world. Suggested new approaches include (1) new cereal food products, (2) water plants as food sources, and (3) the use of microorganisms as a source of high protein materials. (LC)

Innervation and immunohistochemical characteristics of epididymis in Alpaca camelid (Vicugna pacos

Directory of Open Access Journals (Sweden)

Giovanna Liguori

2013-03-01

Full Text Available Alpacas (Vicugna pacos are domesticated camelids indigenous to south America and recently also bred in Europe and Italy for their high quality wool. There is little data available regarding the innervation of the male reproductive tract of this species. In the present study, the distribution of protein gene product 9.5 (PGP 9.5, neuropeptide Y (NPY, tyrosine hydroxilase (TH, calcitonin gene related peptide (CGRP and substance P (SP was analyzed in the epididymis by using immunohistochemical methods. Specimens of the caput, corpus and cauda epididymis were fixed in Bouin’s fluid and processed for immunohistochemistry analysis with primary antibodies against PGP 9.5, NPY, TH, CGRP and SP. Immunopositivity to PGP 9.5 and TH and NPY was observed in nerve fibre bundles and in single nerve fibres contained into the peritubular connective tissue. Many TH and NPY immunopositive cells were found to innervate blood vessels. Rare CGRP and SP immunopositive nerves were observed. Several PGP 9,5 and NPY immunopositive epithelial cells were observed in the caput epididymis. The results of the present study suggest a role for the innervations in modulate reproductive functions in the alpaca epididymis.

Energy and the New World Order

International Nuclear Information System (INIS)

Sander, M.

1997-01-01

Two major trends determine energy demand and supply; population growth and economic growth. This type of analysis very often forgets political and military events, both global and regional. This paper presents the major events influencing energy during the cold war and after the break-up of the USSR in so called ''New World Order'' which have politically and military determined energy supply and demand or, better to say, its price. The main accent is on oil and such events as the OPEC oil embargo in 1973 and the Gulf War in 1991. The relationship between oil and the other forms of primary energy production (coal, nuclear energy) as well as with energy in traffic and transportation are presented. All options in the period that we like to designate with the expression ''New World Order'' one discussed. (author)

Prediction of Packed Cell Volume after Whole Blood Transfusion in Small Ruminants and South American Camelids: 80 Cases (2006–2016)

OpenAIRE

Luethy, D.; Stefanovski, D.; Salber, R.; Sweeney, R.W.

2017-01-01

Background Calculation of desired whole blood transfusion volume relies on an estimate of an animal's circulating blood volume, generally accepted to be 0.08 L/kg or 8% of the animal's body weight in kilograms. Objective To use packed cell volume before and after whole blood transfusion to evaluate the accuracy of a commonly used equation to predict packed cell volume after transfusion in small ruminants and South American camelids; to determine the nature and frequency of adverse transfusion...

The World Language Teacher Shortage: Taking a New Direction

Science.gov (United States)

Swanson, Pete; Mason, Shannon

2018-01-01

Since the end of World War II, international leaders have made calls addressing the world language teacher shortage. For almost 70 years, such rhetoric has been advanced, yet world language teacher shortages remain in many countries such as Australia, Canada, Ireland, New Zealand, the United Kingdom, and the United States. In this article, the…

Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses

Energy Technology Data Exchange (ETDEWEB)

Abraham, Jonathan; Corbett, Kevin D.; Farzan, Michael; Choe, Hyeryun; Harrison, Stephen C. (Harvard-Med)

2010-08-18

New World hemorrhagic fever arenaviruses are rodent-borne agents that cause severe human disease. The GP1 subunit of the surface glycoprotein mediates cell attachment through transferrin receptor 1 (TfR1). We report the structure of Machupo virus (MACV) GP1 bound with human TfR1. Atomic details of the GP1-TfR1 interface clarify the importance of TfR1 residues implicated in New World arenavirus host specificity. Analysis of sequence variation among New World arenavirus GP1s and their host-species receptors, in light of the molecular structure, indicates determinants of viral zoonotic transmission. Infectivities of pseudoviruses in cells expressing mutated TfR1 confirm that contacts at the tip of the TfR1 apical domain determine the capacity of human TfR1 to mediate infection by particular New World arenaviruses. We propose that New World arenaviruses that are pathogenic to humans fortuitously acquired affinity for human TfR1 during adaptation to TfR1 of their natural hosts.

Film, Philosophy, and Terrence Malick's "The New World"

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Sterritt, David

2006-01-01

Director Terence Malick's movies contain his distinctive trademarks, namely sumptuous images of the natural world, a great deal of voice-over monologue, and an exploration of philosophical issues such as the purpose of life and the meaning of death. Malick's film "The New World" affords him a prefect opportunity to examine contrasts between the…

South Africa: the new world of disability.

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Coetzer, Pieter

2008-01-01

Over the past 10 years, unique business imperatives in South Africa have led to innovative risk product design, some of which are still unfamiliar to the rest of the world. The main drivers are: the unique mix of first- and third-world societies in our country, and an energetic marketing force operating in an already highly saturated insurance market. As a result, new product design has become one of the most effective ways to grow new business volumes in this competitive environment. This article reviews some of the unique products available and their advantages, target markets and disadvantages. The products that are discussed include lump sum total and permanent disability benefits, extended critical illness products, cover for impairment of function as well as risk products for people living with HIV/AIDS.

Resurrection of the genus Aphyllon for New World broomrapes (Orobanche s.l., Orobanchaceae).

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Schneider, Adam C

2016-01-01

Recent phylogenetic studies support a monophyletic clade of New World broomrapes (Orobanche sects. Gymnocaulis and Nothaphyllon) sister to the Old World genus Phelipanche. I place the New World taxa in the genus Aphyllon, propose 21 new combinations, and provide a list of currently accepted taxa.

Osteometría y genética de los camélidos mochica, costa norte del Perú

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Víctor F. Vásquez Sánchez

2009-09-01

Full Text Available The objective of this study was to evaluate the results of osteometric analyses applied to camelid bones samples from Moche sites (I and VII AD located on the north coast of Peru. The bones analyzed in this study correspond to first phalanges from two Moche archaeological sites (Cerro Chepén and Moche Urban Zone. Discriminant analysis was conducted on a sample of 44 first phalanges, taking into account five measurments in each bone. The results showed the identification in both sites of two species of domestic camelids, Lama glama “llama” and Lama pacos“alpaca.” The interpretation of the results is discussed by explaining a model of geographic or vicariant speciation of camelids that inhabited the coast of Peru during Moche times. This model takes into account that in this environment currently camelids are not breed, as well as genetics and evolutionary factors in the new domestic form, the effect of Bergmann’s Rule, and new grasses in the morphology of this new form of domestic camelid, ,which lived in the region at the time of Moche.

Resurrection of the genus Aphyllon for New World broomrapes (Orobanche s.l., Orobanchaceae

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Adam C. Schneider

2016-12-01

Full Text Available Recent phylogenetic studies support a monophyletic clade of New World broomrapes (Orobanche sects. Gymnocaulis and Nothaphyllon sister to the Old World genus Phelipanche. I place the New World taxa in the genus Aphyllon, propose 21 new combinations, and provide a list of currently accepted taxa.

Optical performance of the New Worlds Occulter

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Arenberg, Jonathan W.; Lo, Amy S.; Glassman, Tiffany M.; Cash, Webster

2007-04-01

The New Worlds Observer (NWO) is a multiple spacecraft mission that is capable of detecting and characterizing extra-solar planets and planetary systems. NWO consists of an external occulter and a generic space telescope, flying in tandem. The external occulter has specific requirements on its shape and size, while the telescope needs no special modification beyond that required to do high-quality astrophysical observations. The occulter is a petal-shaped, opaque screen that creates a high-suppression shadow large enough to accommodate the telescope. This article reports on the optical performance of the novel New Worlds occulter design. It also introduces two new aspects of its optical performance which enhance the detectability of extra-solar planets. We also include a brief discussion of the buildability and the tolerances of the occulter. It is also shown that an occulter design can be found for any set of science requirements. We show that NWO is a viable mission concept for the study of extra-solar planets. To cite this article: J.W. Arenberg et al., C. R. Physique 8 (2007).

NASA World Wind: A New Mission

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Hogan, P.; Gaskins, T.; Bailey, J. E.

2008-12-01

Virtual Globes are well into their first generation, providing increasingly rich and beautiful visualization of more types and quantities of information. However, they are still mostly single and proprietary programs, akin to a web browser whose content and functionality are controlled and constrained largely by the browser's manufacturer. Today Google and Microsoft determine what we can and cannot see and do in these programs. NASA World Wind started out in nearly the same mode, a single program with limited functionality and information content. But as the possibilities of virtual globes became more apparent, we found that while enabling a new class of information visualization, we were also getting in the way. Many users want to provide World Wind functionality and information in their programs, not ours. They want it in their web pages. They want to include their own features. They told us that only with this kind of flexibility, could their objectives and the potential of the technology be truly realized. World Wind therefore changed its mission: from providing a single information browser to enabling a whole class of 3D geographic applications. Instead of creating one program, we create components to be used in any number of programs. World Wind is NASA open source software. With the source code being fully visible, anyone can readily use it and freely extend it to serve any use. Imagery and other information provided by the World Wind servers is also free and unencumbered, including the server technology to deliver geospatial data. World Wind developers can therefore provide exclusive and custom solutions based on user needs.

Assessment of the effects of epinephrine and insulin on plasma and serum biochemical variables in llamas and alpacas.

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Cebra, Christopher K; Tornquist, Susan J

2004-12-01

To describe the metabolic effects of epinephrine administration in New World camelids and investigate whether these effects are influenced by administration of insulin. 6 llamas and 8 alpacas (all adult castrated males). Prior to each experiment, food was withheld from camelids for 8 hours. On each of 2 consecutive days, alpacas were administered epinephrine (10 mg/kg, IM; time 0); alpacas were randomly assigned to receive regular insulin (0.2 U/kg, IV) immediately after epinephrine administration on one of those days. In llamas, the experiment was performed once after administration of epinephrine only. At 0, 30, 60, 90, 120, 150, 180, 210, and 240 minutes after treatment, blood samples were collected and several serum or plasma biochemical variables were assessed; in addition, plasma samples from llamas were assessed for insulin concentrations. Data were compared between days (alpacas only) and between time points. Administration of epinephrine induced mobilization of glucose, triglycerides, nonesterified fatty acids, and beta-hydroxybutyrate. A small increase in endogenous insulin concentration was detected in epinephrine-treated llamas, compared with baseline values. Overall, insulin administration decreased, negated, or delayed the epinephrine-associated increases in serum or plasma concentrations of circulating energy substrates, except that it augmented the epinephrine-associated increase in concentration of triglycerides. Epinephrine appeared to mobilize energy substrates in camelids and hence may be involved in the pathogenesis of disorders of glucose and fat metabolism. Insulin appeared to antagonize most of these effects, and its administration may have therapeutic value in camelids.

THE U.S. AS THE NEW ROME: DISPUTING THE NEW WORLD ORDER

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O. I. Ivonina

2016-01-01

Full Text Available The starting point of the conclusions of politicians and experts was the recognition of the changed nature of threats to the New World Order. In post-Westfalia system of international relations the main actors are not sovereigns, but transnational actors of world politics, including transnational terrorist and criminal networks. In this situation, the support of global security threat serves the underground world – terrorists, shady business structures, failed states. The unconventional nature of the threat to peace and stability of the New World Order requires an equally innovative response which transcends the formal constraints of international law and the traditional doctrine of deterrence. An analysis of the U.S. foreign policy concepts suggests that today’s academic and political community has promoted consensus of neoliberals and neoconservatives, supporters of the institutional functionalism and representatives of the school of Realpolitik. This consensus was based on the recognition of the admissibility of pre-emptive strikes on the territory of failed states, sponsoring international terrorism, or the implementation of open interference in the internal affairs of “rogue states” for human rights and democratic freedoms guarantee.

Glocal spirituality for a brave new world

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Antoon Geels

2009-01-01

Full Text Available Spirituality, as it is presented in this article, can serve as an antidote to an all too disrespectful attitude towards our fellow human beings, towards life in general. Spirituality might unite a greater part of the world in the battle for survival. Our world, Gaia, is threatened, as we all know. Apart from the usual disasters as seemingly never-ending wars and conflicts we now also have to confront global threats such as climate changes, global pollution, and food distribution problems. In such a world everything has to be done in order to promote the fundamental idea that we only have one planet and one humanity.Spirituality addresses such issues. The purpose of this paper is to show that people who express the view that they are ‘spiritual, not religious’, people belonging to what can be called the new spirituality, despite their aversion to institutionalized religion never­theless exhibit elements in their belief-systems that are closely related to the great mystical traditions in world religion. These common denominators are, a good ground for dialogue. When theologians from especially the theistic traditions more often than not search for differences, mystics and representatives for the new spirituality are more inclined to find commonalities. At a time when elements of traditional Christianity such as the belief in a transcendent God show signs of being in decline, there seems to be an increasing interest in the predominant mystical and panentheistic view of God, stating that God is both immanent and transcendent.

Enhanced expression and purification of camelid single domain VHH antibodies from classical inclusion bodies.

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Maggi, Maristella; Scotti, Claudia

2017-08-01

Single domain antibodies (sdAbs) are small antigen-binding domains derived from naturally occurring, heavy chain-only immunoglobulins isolated from camelid and sharks. They maintain the same binding capability of full-length IgGs but with improved thermal stability and permeability, which justifies their scientific, medical and industrial interest. Several described recombinant forms of sdAbs have been produced in different hosts and with different strategies. Here we present an optimized method for a time-saving, high yield production and extraction of a poly-histidine-tagged sdAb from Escherichia coli classical inclusion bodies. Protein expression and extraction were attempted using 4 different methods (e.g. autoinducing or IPTG-induced soluble expression, non-classical and classical inclusion bodies). The best method resulted to be expression in classical inclusion bodies and urea-mediated protein extraction which yielded 60-70 mg/l bacterial culture. The method we here describe can be of general interest for an enhanced and efficient heterologous expression of sdAbs for research and industrial purposes. Copyright © 2017 Elsevier Inc. All rights reserved.

Towards the New World Order: Theoretical Interpretations and Practical Implementations

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K. A. Efremova

2016-01-01

Full Text Available The problem of political and economic regulation of contemporary global transformations, taken in the context of the New World Order discourse, attracts attention in Russia and abroad alike. Considering this problem, British analysts Ken Booth and Nickolas Wheeler underline three major approaches to security dilemma, namely, fatalist, mitigator, and transcender logics. Followers of the fatalist approach (neo-realists, globalists believe that world order is a zero-sum game, where interstate interactions are mostly confrontational, and their pattern depends on the current balance of power. Mitigators (neo-liberals, functionalists, constructivists, etc. insist that the emerging world order is a win-win game, where nations opt for investing some of their sovereignty into newly created international institutions (regimes and organizations, hoping that conventional rules adopted by them would help to decrease international uncertainty, which otherwise might lead to confrontation. Transcenders (neo-Marxists, feminists, anarchists, federalists, etc. consider the existing world order an archaic one, calling for a new, fair and humane pattern of international relations. According to their logic, the new world order is the end of the game among sovereign states, because it derives from the idea of humankind not divided by national boundaries but united into a global transnational society.

FORMATION OF THE NEW WORLD VIEW, NEW PERSON, NEW SOCIETY OF THE FUTURE

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Valentina A. Voronkova

2013-09-01

Full Text Available Objective: To substantiate the anthropological approaches to the definition of the noosphere and cosmic consciousness and the world, a new consciousness, a new man, a new society of the future, by which humankind can go to a new state of mutual responsibility. Society should be based on a spiritual basis, a person must develop in harmony with the universe, so the philosophers need to change the philosophy of survival of the globalized world in the development of philosophy and spirituality, which is a new matrix of the discourse of development and outlook of the universe. The meaning of the individual in society - to be useful to society and to the person, to be a master, to live in harmony with people and nature. Methodology. Study is based on the methd of hermeneutical analysis.The scientific novelty of this work is shown in the results, which indicate the formation of the noosphere worldview that seeks to realize the idea of V.Vernadsky, which manifests itself in the context of a harmonious relationship of scientific knowledge, philosophy, and religion, which produce a variety of forms of dialogue between people of different cultural backgrounds, nationalities, religions, generations and gender. Conclusions. The new philosophy of development in the twenty-first century, aimed at forming a new society, a new consciousness, a new person should be directed to: a the confrontation process of self-destruction of the human person and the destructive tendencies of the environment, and b the creation of conditions for the harmonization of public self-regulatory systems: organization, person, environment, society, and c the creation of conditions for the realization of the creative potential of every person (regardless of its level of consciousness to identify the direction of development of the creative work, and d the formation and implementation of creative management at all levels.

TOURISM AS AN ENABLER INTO THE NEW GLOBAL WORLD

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ROTARIU ILIE

2014-12-01

Full Text Available During the last decades a new world has been developed, characterized not only by huge technical discoveries but also by tremendous social changes, because of the transformation of the human been philosophy and way of living. We have assisted in the developed countries to the issue, expansion and now transformation of the classical economy into leisure, experiences and now transformation. In the emerging countries the influence is high, stressing for the population which has to face the abundance of the markets, the new “brain cleaning” by mass media and the compulsory need to integrate into the new world. Philosophy, science, tradition, national behaviors and science have generated a melting pot where the common people has to swim to reach the feeling of happiness. Even the classical PIB is replaced by the Index of Happiness. Tourism is in the middle and seems to be a perfect tool to find a theoretical, but manly a practical issue. New forms of tourism have led to the need of reconsideration even of the definition of the tourism. The paper wants to be an opening for a broader discussion of the role and future of tourism as an enabler into the global leisure world.

Parallel evolution of the glycogen synthase 1 (muscle) gene Gys1 between Old World and New World fruit bats (Order: Chiroptera).

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Fang, Lu; Shen, Bin; Irwin, David M; Zhang, Shuyi

2014-10-01

Glycogen synthase, which catalyzes the synthesis of glycogen, is especially important for Old World (Pteropodidae) and New World (Phyllostomidae) fruit bats that ingest high-carbohydrate diets. Glycogen synthase 1, encoded by the Gys1 gene, is the glycogen synthase isozyme that functions in muscles. To determine whether Gys1 has undergone adaptive evolution in bats with carbohydrate-rich diets, in comparison to insect-eating sister bat taxa, we sequenced the coding region of the Gys1 gene from 10 species of bats, including two Old World fruit bats (Pteropodidae) and a New World fruit bat (Phyllostomidae). Our results show no evidence for positive selection in the Gys1 coding sequence on the ancestral Old World and the New World Artibeus lituratus branches. Tests for convergent evolution indicated convergence of the sequences and one parallel amino acid substitution (T395A) was detected on these branches, which was likely driven by natural selection.

Tracking Alu evolution in New World primates

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Batzer Mark A

2005-10-01

Full Text Available Abstract Background Alu elements are Short INterspersed Elements (SINEs in primate genomes that have proven useful as markers for studying genome evolution, population biology and phylogenetics. Most of these applications, however, have been limited to humans and their nearest relatives, chimpanzees. In an effort to expand our understanding of Alu sequence evolution and to increase the applicability of these markers to non-human primate biology, we have analyzed available Alu sequences for loci specific to platyrrhine (New World primates. Results Branching patterns along an Alu sequence phylogeny indicate three major classes of platyrrhine-specific Alu sequences. Sequence comparisons further reveal at least three New World monkey-specific subfamilies; AluTa7, AluTa10, and AluTa15. Two of these subfamilies appear to be derived from a gene conversion event that has produced a recently active fusion of AluSc- and AluSp-type elements. This is a novel mode of origin for new Alu subfamilies. Conclusion The use of Alu elements as genetic markers in studies of genome evolution, phylogenetics, and population biology has been very productive when applied to humans. The characterization of these three new Alu subfamilies not only increases our understanding of Alu sequence evolution in primates, but also opens the door to the application of these genetic markers outside the hominid lineage.

Variation in Bluetongue virus real-time reverse transcription polymerase chain reaction assay results in blood samples of sheep, cattle, and alpaca.

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Brito, Barbara P; Gardner, Ian A; Hietala, Sharon K; Crossley, Beate M

2011-07-01

Bluetongue is a vector-borne viral disease that affects domestic and wild ruminants. The epidemiology of this disease has recently changed, with occurrence in new geographic areas. Various real-time quantitative reverse transcription polymerase chain reaction (real-time qRT-PCR) assays are used to detect Bluetongue virus (BTV); however, the impact of biologic differences between New World camelids and domestic ruminant samples on PCR efficiency, for which the BTV real-time qRT-PCR was initially validated are unknown. New world camelids are known to have important biologic differences in whole blood composition, including hemoglobin concentration, which can alter PCR performance. In the present study, sheep, cattle, and alpaca blood were spiked with BTV serotypes 10, 11, 13, and 17 and analyzed in 10-fold dilutions by real-time qRT-PCR to determine if species affected nucleic acid recovery and assay performance. A separate experiment was performed using spiked alpaca blood subsequently diluted in 10-fold series in sheep blood to assess the influence of alpaca blood on performance efficiency of the BTV real-time qRT-PCR assay. Results showed that BTV-specific nucleic acid detection from alpaca blood was consistently 1-2 logs lower than from sheep and cattle blood, and results were similar for each of the 4 BTV serotypes analyzed.

New World Tryptamine Hallucinogens and the Neuroscience of Ayahuasca.

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McKenna, Dennis; Riba, Jordi

2018-01-01

New World indigenous peoples are noted for their sophisticated use of psychedelic plants in shamanic and ethnomedical practices. The use of psychedelic plant preparations among New World tribes is far more prevalent than in the Old World. Yet, although these preparations are botanically diverse, almost all are chemically similar in that their active principles are tryptamine derivatives, either DMT or related constituents. Part 1 of this paper provides an ethnopharmacological overview of the major tryptamine-containing New World hallucinogens. Part 2 focuses on ayahuasca and its effects on the human brain. Using complementary neurophysiological and neuroimaging techniques, we have identified brain areas involved in the cognitive effects induced by this complex botanical preparation. Initial SPECT data showed that ayahuasca modulated activity in higher order association areas of the brain. Increased blood perfusion was observed mainly in anterior brain regions encompassing the frontomedial and anterior cingulate cortices of the frontal lobes, and in the medial regions of the temporal lobes. On the other hand, applying spectral analysis and source location techniques to cortical electrical signals, we found changes in neuronal activity that predominated in more posterior sensory-selective areas of the brain. Now, using functional connectivity analysis of brain oscillations we have been able to reconcile these seemingly contradictory findings. By measuring transfer entropy, a metric based on information theory, we have shown that ayahuasca temporarily modifies the ordinary flow of information within the brain. We propose a model in which ayahuasca reduces top-down constraints and facilitates bottom-up information transfer. By simultaneously enhancing endogenous cortical excitability and reducing higher-order cognitive control, ayahuasca temporarily disrupts neural hierarchies allowing inner exploration and a new outlook on reality.

The new world atlas of artificial night sky brightness.

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Falchi, Fabio; Cinzano, Pierantonio; Duriscoe, Dan; Kyba, Christopher C M; Elvidge, Christopher D; Baugh, Kimberly; Portnov, Boris A; Rybnikova, Nataliya A; Furgoni, Riccardo

2016-06-01

Artificial lights raise night sky luminance, creating the most visible effect of light pollution-artificial skyglow. Despite the increasing interest among scientists in fields such as ecology, astronomy, health care, and land-use planning, light pollution lacks a current quantification of its magnitude on a global scale. To overcome this, we present the world atlas of artificial sky luminance, computed with our light pollution propagation software using new high-resolution satellite data and new precision sky brightness measurements. This atlas shows that more than 80% of the world and more than 99% of the U.S. and European populations live under light-polluted skies. The Milky Way is hidden from more than one-third of humanity, including 60% of Europeans and nearly 80% of North Americans. Moreover, 23% of the world's land surfaces between 75°N and 60°S, 88% of Europe, and almost half of the United States experience light-polluted nights.

World-Economy Centrality and Carbon Dioxide Emissions: A New Look at the Position in the Capitalist World-System and Environmental Pollution

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Paul Prew

2015-08-01

Full Text Available With the ever-growing concern of climate change, much attention has been paid to the factors driving carbon dioxide emissions. Previous research in the World-Systems perspective has identified a relationship between carbon dioxide emissions and position in the world-economy. This study intends to build on the previous research by developing a new, more parsimonious indicator of World-System position based on Immanuel Wallerstein’s theoretical concepts of incorporation and core-periphery processes. The new World-System indicator is derived from the centrality measure in network analysis based on import data from the International Monetary Fund’s Direction of Trade Statistics. Based on the theoretical concepts of core-periphery processes, carbon dioxide emissions are predicted to rise based on the predominance of energy-intensive, high-technology, core processes within the nation. The results tend to demonstrate a strong relationship between carbon dioxide emissions and position in the world-economy, and the new World-System position indicator is more strongly related with carbon dioxide emissions than Gross Domestic Product per capita.

The Old and New RNA World

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Zofia Szweykowska-Kulińska

2014-12-01

Full Text Available Among the numerous hypotheses offering a scenario for the origin of life on Earth, the one called “The RNA World” has gained the most attention. According to this hypothesis RNA acted as a genetic information storage material, as a catalyst of all metabolic reactions, and as a regulator of all processes in the primordial world. Various experiments show that RNA molecules could have been synthesized abiotically, with the potential to mediate a whole repertoire of metabolic reactions. Ribozymes carrying out aminoacyl-tRNA reactions have been found in SELEX (systematic evolution of ligands by exponential enrichment approaches and the development of a ribosome from a RNA-built protoribosome is easy to imagine. Transfer RNA aminoacylation, protoribosome origin, and the availability of amino acids on early Earth allowed the genetic code to evolve. Encoded proteins most likely stabilized RNA molecules and were able to create channels across membranes. In the modern cell, DNA replaced RNA as the main depositor of genetic information and proteins carry out almost all metabolic reactions. However, RNA is still playing versatile, crucial roles in the cell. Apart from its classical functions in the cell, a huge small RNA world is controlling gene expression, chromatin condensation, response to environmental cues, and protecting the cell against the invasion of various nucleic acids forms. Long non-coding RNAs act as crucial gene expression regulators. Riboswitches act at the level of transcription, splicing or translation and mediate feedback regulation on biosynthesis and transport of the ligand they sense. Alternative splicing generates genetic variability and increases the protein repertoire in response to developmental or environmental changes. All these regulatory functions are essential in shaping cell plasticity in the changing milieu. Recent discoveries of new, unexpected and important functions of RNA molecules support the hypothesis that we

Carpal valgus in llamas and alpacas: Retrospective evaluation of patient characteristics, radiographic features and outcomes following surgical treatment

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Hunter, Barbara; Duesterdieck-Zellmer, Katja F.; Huber, Michael J.; Parker, Jill E.; Semevolos, Stacy A.

2014-01-01

This study evaluated outcomes of surgical treatment for carpal valgus in New World camelids and correlated successful outcome (absence of carpal valgus determined by a veterinarian) with patient characteristics and radiographic features. Univariable and multivariable analyses of retrospective case data in 19 camelids (33 limbs) treated for carpal valgus between 1987 and 2010 revealed that procedures incorporating a distal radial transphyseal bridge were more likely (P = 0.03) to result in success after a single surgical procedure. A greater degree of angulation (> 19°, P = 0.02) and younger age at surgery (< 4 months, P = 0.03) were associated with unsuccessful outcome. Overall, 74% of limbs straightened, 15% overcorrected, and 11% had persistent valgus following surgical intervention. To straighten, 22% of limbs required multiple procedures, not including implant removal. According to owners, valgus returned following implant removal in 4 limbs that had straightened after surgery. PMID:25477542

The Global Lives Project: Making New Media Matter in a Global World

DEFF Research Database (Denmark)

Hasse Jørgensen, Stina

2010-01-01

Computing has infiltrated the everyday life of people all over the world. It is no longer merely a tool for communication and interaction, but also something-to-think-with, a medium that can give us new dimensions in the way we experience and engage with the world.Critical computing evokes...... in the user new ways of thinking and interacting with a globalized world. The Global Lives Project is a compelling example of this usage of computing technology. The GLP archive, which contains visual documentation of the lives of different people from around the world on a digital platform on the Internet......, enables users to actively engage with global cultures. As a critical computing project, the Global Lives Project hopes to bring a critical awareness of how culture is categorized and transformed by engaging users in a collaborative new media project....

World is looking for new resources and fuels

International Nuclear Information System (INIS)

Schoenwiesner, R.; Prosnan, J.

2003-01-01

Until 1900 the mankind used burning coal and wood to gain energy. The last century was more dedicated to oil and gas. Only oil could ensure a relatively sufficient quantity of energy supplied by a relatively small volume of fuel and so the transport could start to develop. But the world oil and gas supplies are limited and the this fact together with environmental issues urge the governments, companies and individuals to search for alternative sources of energy. Over 40 percent of the world's oil production is used up by transport and so, and not only in the opinion of the Head of Fuel Cell Activities Division of General Motors J. Byron McCormic, the world has to look for new resources and fuels to be used in transport. Hydrogen is the most promising one

A New World Information Order for Better Human Understanding.

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Masmoudi, Mustapha

Many studies, particularly the report of the International Commission for the Study of Communication Problems (ICSCP), have tried to define a new world information order for better human understanding. What appears to be needed is the establishment of a new, open-ended, conceptual framework leading to a freer, more efficient, more equitable,…

Toxoplasmosis in a colony of New World monkeys

DEFF Research Database (Denmark)

Dietz, H.H.; Henriksen, P.; Bille-Hansen, Vivi

1997-01-01

In a colony of New World monkeys five tamarins (Saguinus oedipus, Saguinus labiatus and Leontopithecus rosal. rosal.), three marmosets (Callithrix jacchus and Callithrix pygmaea) and one saki (Pithecia pithecia) died suddenly. The colony comprised 16 marmosets, 10 tamarins and three sakis. The ma...

New contractual trends in world petroleum industry

International Nuclear Information System (INIS)

Arzu, M.; Clerici, C.

1992-01-01

Oil industry contractual practices have gone through a rapid evolution starting from the 1970's, mainly determined by a change in the relationship between producer and consumer countries. Current steady price trends have led to a new equilibrium causing the petroleum companies and producer countries to re-examine their contractual strategies. This article highlights the new contractual trends in the petroleum industry by tracing the evolution of international business relationships and by comparing the main types of contractual schemes, e.g., concession, production sharing, services and services support, adopted today by the key hydrocarbon producing countries of the world

New world bats harbor diverse influenza A viruses.

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Suxiang Tong

Full Text Available Aquatic birds harbor diverse influenza A viruses and are a major viral reservoir in nature. The recent discovery of influenza viruses of a new H17N10 subtype in Central American fruit bats suggests that other New World species may similarly carry divergent influenza viruses. Using consensus degenerate RT-PCR, we identified a novel influenza A virus, designated as H18N11, in a flat-faced fruit bat (Artibeus planirostris from Peru. Serologic studies with the recombinant H18 protein indicated that several Peruvian bat species were infected by this virus. Phylogenetic analyses demonstrate that, in some gene segments, New World bats harbor more influenza virus genetic diversity than all other mammalian and avian species combined, indicative of a long-standing host-virus association. Structural and functional analyses of the hemagglutinin and neuraminidase indicate that sialic acid is not a ligand for virus attachment nor a substrate for release, suggesting a unique mode of influenza A virus attachment and activation of membrane fusion for entry into host cells. Taken together, these findings indicate that bats constitute a potentially important and likely ancient reservoir for a diverse pool of influenza viruses.

Old World hantaviruses in rodents in New Orleans, Louisiana.

Science.gov (United States)

Cross, Robert W; Waffa, Bradley; Freeman, Ashley; Riegel, Claudia; Moses, Lina M; Bennett, Andrew; Safronetz, David; Fischer, Elizabeth R; Feldmann, Heinz; Voss, Thomas G; Bausch, Daniel G

2014-05-01

Seoul virus, an Old World hantavirus, is maintained in brown rats and causes a mild form of hemorrhagic fever with renal syndrome (HFRS) in humans. We captured rodents in New Orleans, Louisiana and tested them for the presence of Old World hantaviruses by reverse transcription polymerase chain reaction (RT-PCR) with sequencing, cell culture, and electron microscopy; 6 (3.4%) of 178 rodents captured--all brown rats--were positive for a Seoul virus variant previously coined Tchoupitoulas virus, which was noted in rodents in New Orleans in the 1980s. The finding of Tchoupitoulas virus in New Orleans over 25 years since its first discovery suggests stable endemicity in the city. Although the degree to which this virus causes human infection and disease remains unknown, repeated demonstration of Seoul virus in rodent populations, recent cases of laboratory-confirmed HFRS in some US cities, and a possible link with hypertensive renal disease warrant additional investigation in both rodents and humans.

Polymorphic New World monkeys with more than three M/L cone types

Science.gov (United States)

Jacobs, Gerald H.; Deegan, Jess F.

2005-10-01

Most New World (platyrrhine) monkeys have M/L cone photopigment polymorphisms that map directly into individual variations in visual sensitivity and color vision. We used electroretinogram flicker photometry to examine M/L cone photopigments in the New World monkey Callicebus moloch (the dusky Titi). Like other New World monkeys, this species has an M/L cone photopigment polymorphism that reflects the presence of X-chromosome opsin gene alleles. However, unlike other platyrrhines in which three M/L photopigments are typical, Callicebus has a total of five M/L cone photopigments. The peak sensitivity values for these pigments extend across the range from 530 to 562 nm. The result is an enhanced array of potential color vision phenotypes in this species.

Modern Exploration of Galileo's New Worlds

Science.gov (United States)

Johnson, Torrence V.

2010-01-01

Four hundred years ago Galileo turned his telescope to the heavens and changed the way we view the cosmos forever. Among his discoveries in January of 1610 were four new 'stars', following Jupiter in the sky but changing their positions with respect to the giant planet every night. Galileo showed that these 'Medicean stars', as he named them, were moons orbiting Jupiter in the same manner that the Earth and planets revolve about the Sun in the Copernican theory of the solar system. Over the next three centuries these moons, now collectively named the Galilean satellites after their discoverer, remained tiny dots of light in astronomers' telescopes. In the latter portion of the twentieth century Galileo's new worlds became important targets of exploration by robotic spacecraft. This paper reviews the history of this exploration through the discoveries made by the Galileo mission from 1995 to 2003, setting the stage for on-going exploration in the new century.

Differential Recognition of Old World and New World Arenavirus Envelope Glycoproteins by Subtilisin Kexin Isozyme 1 (SKI-1)/Site 1 Protease (S1P)

Science.gov (United States)

Burri, Dominique J.; Ramos da Palma, Joel; Seidah, Nabil G.; Zanotti, Giuseppe; Cendron, Laura

2013-01-01

The arenaviruses are an important family of emerging viruses that includes several causative agents of severe hemorrhagic fevers in humans that represent serious public health problems. A crucial step of the arenavirus life cycle is maturation of the envelope glycoprotein precursor (GPC) by the cellular subtilisin kexin isozyme 1 (SKI-1)/site 1 protease (S1P). Comparison of the currently known sequences of arenavirus GPCs revealed the presence of a highly conserved aromatic residue at position P7 relative to the SKI-1/S1P cleavage side in Old World and clade C New World arenaviruses but not in New World viruses of clades A and B or cellular substrates of SKI-1/S1P. Using a combination of molecular modeling and structure-function analysis, we found that residueY285 of SKI-1/S1P, distal from the catalytic triad, is implicated in the molecular recognition of the aromatic “signature residue” at P7 in the GPC of Old World Lassa virus. Using a quantitative biochemical approach, we show that Y285 of SKI-1/S1P is crucial for the efficient processing of peptides derived from Old World and clade C New World arenavirus GPCs but not of those from clade A and B New World arenavirus GPCs. The data suggest that during coevolution with their mammalian hosts, GPCs of Old World and clade C New World viruses expanded the molecular contacts with SKI-1/S1P beyond the classical four-amino-acid recognition sequences and currently occupy an extended binding pocket. PMID:23536681

Persistent Bovine Viral Diarrhea Virus infection in domestic and wild small ruminants and camelids including the mountain goat (Oreamnos americanus

Directory of Open Access Journals (Sweden)

Danielle Darracq Nelson

2016-01-01

Full Text Available Bovine viral diarrhea virus (BVDV is a Pestivirus best known for causing a variety of disease syndromes in cattle, including gastrointestinal disease, reproductive insufficiency, immunosuppression, mucosal disease, and hemorrhagic syndrome. The virus can be spread by transiently infected individuals and by persistently infected animals that may be asymptomatic while shedding large amounts of virus throughout their lifetime. BVDV has been reported in over 40 domestic and free-ranging species, and persistent infection has been described in eight of those species: white-tailed deer, mule deer, eland, mousedeer, mountain goats, alpacas, sheep, and domestic swine. This paper reviews the various aspects of BVDV transmission, disease syndromes, diagnosis, control, and prevention, as well as examines BVDV infection in domestic and wild small ruminants and camelids including mountain goats (Oreamnos americanus.

Experimental infection of South American camelids with bluetongue virus serotype 8.

Science.gov (United States)

Schulz, Claudia; Eschbaumer, Michael; Rudolf, Miriam; König, Patricia; Keller, Markus; Bauer, Christian; Gauly, Matthias; Grevelding, Christoph G; Beer, Martin; Hoffmann, Bernd

2012-01-27

Bluetongue (BT) is an infectious, non-contagious disease of wild and domestic ruminants. It is caused by bluetongue virus (BTV) and transmitted by Culicoides biting midges. Since 1998, BT has been emerging throughout Europe, threatening not only the naïve ruminant population. Historically, South American camelids (SAC) were considered to be resistant to BT disease. However, recent fatalities related to BTV in captive SAC have raised questions about their role in BTV epidemiology. Data on the susceptibility of SAC to experimental infection with BTV serotype 8 (BTV-8) were collected in an animal experiment. Three alpacas (Vicugna pacos) and three llamas (Lama glama) were experimentally infected with BTV-8. They displayed very mild clinical signs. Seroconversion was first measured 6-8 days after infection (dpi) by ELISA, and neutralising antibodies appeared 10-13 dpi. BTV-8 RNA levels in blood were very low, and quickly cleared after seroconversion. However, spleens collected post-mortem were still positive for BTV RNA, over 71 days after the last detection in blood samples. Virus isolation was only possible from blood samples of two alpacas by inoculation of highly sensitive interferon alpha/beta receptor-deficient (IFNAR(-/-)) mice. An in vitro experiment demonstrated that significantly lower amounts of BTV-8 adsorb to SAC blood cells than to bovine blood cells. Although this experiment showed that SAC are generally susceptible to a BTV-8 infection, it indicates that these species play a negligible role in BTV epidemiology. Copyright © 2011 Elsevier B.V. All rights reserved.

The genetic prehistory of the New World Arctic

DEFF Research Database (Denmark)

Raghavan, Maanasa; DeGiorgio, Michael; Albrechtsen, Anders

2014-01-01

The New World Arctic, the last region of the Americas to be populated by humans, has a relatively well-researched archaeology, but an understanding of its genetic history is lacking. We present genome-wide sequence data from ancient and present-day humans from Greenland, Arctic Canada, Alaska, Al...

New Challenges in the Narcotics World

Directory of Open Access Journals (Sweden)

Nicoleta-Elena Buzatu

2011-05-01

Full Text Available The consumption of narcotics is one of the problems the international world is confronted withnowadays; its direct or indirect effects lead to the conclusion that it represents a worrying phenomenon meantto be taken into account by the international programs of co-operation. In contrast with the mature population,the younger population is much more receptive to the new, much more attracted by new experiments and,consequently, by risks. The narcotics flagellum is one of the most complex, profound and dramaticphenomena met with in the contemporary world. Narcotization is the morbid habit of repeatedly taking andusing ever higher doses of more or less toxic substances able to generate a psychological and physicaladdiction to them. Unhappily due to the lack of information, people think that the illegal substances only –heroine, marijuana, cocaine, etc. – are considered drugs. Not long ago there appeared the so-called “mixes ofethno-botanical plants” that are perfectly legal, and many consumers have replaced narcotics - as marijuana,for example - with plant mixes. According to explanations given by the Ethno-botanical ExplanatoryDictionary, ethno-biology is a branch that studies the mutual relationship between man and plant. InRomania, ethno-botanical plants are sold under the generic names of “aroma therapeutic” or “ethnobotanical”plants. The numerous researches meant to decode the molecular and biochemical structure of theseherbs, the researchers found that consumers are described as facing hallucinogenic effects caused by somesynthetic substances - cannabinoids - added by manufacturers.

The new ICSU World Data System: Building on the 50 Year Legacy of the World Data Centers

Science.gov (United States)

Clark, D. M.; Minster, J.

2008-12-01

The International Council for Science (ICSU) World Data Center (WDC) system was established in 1957 in response to the data needs of the International Geophysical Year (IGY). Its holdings included a wide range of solar, geophysical, environmental, and human dimensions data. The WDC system developed many innovative data management and data exchange procedures and techniques over the last 50 years, which mitigated effectively the impact of global politics on science. The beginning of the 21st century has seen new ICSU requirements for management of large and diverse scientific data from major international programs such as the Group on Earth Observations (GEO) Global Earth Observation Systems of Systems (GEOSS), the International Polar Year (IPY), the Millennium Ecosystems Assessment (MEA), and the Coordinated Energy and Water Cycle Observation Project (CEOP). As a consequence, a completely new ICSU data activity, the World Data System (WDS) is being created which will incorporate the major ICSU data activities including in particular the WDCs and the Federation of Astronomical and Geophysical Data- Analysis Services. Using the legacy of the WDC system, the WDS will place an emphasis on new information technology as applied to modern data management techniques and international data exchange. The new World Data System will support ICSU's enduring mission and objectives, ensuring the long-term stewardship and provision of quality-assessed data and data services to the international science community and other stakeholders. It will have a broader disciplinary and geographic base than the current ICSU networks and be recognized as a world-wide "community of excellence" for data issues. It will use state-of-the-art systems interoperability, international very high bandwidth capabilities and a coordinated focus on topics such as virtual observatories. It will also encourage the establishment of new data centers and services, using modern paradigms for their establishment

Identification of Lamanema chavezi Becklund 1963 infection in a llama (Lama glama) in the United States.

Science.gov (United States)

Jarvinen, Julie Ann C; Whitley, Elizabeth M; Kreuder, Amanda J; Schleining, Jennifer A

2014-01-01

Infection with Lamanema chavezi, a parasitic nematode of New World camelids, was diagnosed by examination of feces and formalin-fixed liver from a 14-month-old female llama (Lama glama) that died after a 6-week illness. Infection with L. chavezi was initially suspected when a granuloma containing an unidentified nematode was detected microscopically in the hepatic parenchyma from a necropsy specimen. The subsequent diagnosis of L. chavezi infection was based on the morphologic features of 2 immature nematodes dissected from individual hepatic granulomas, characteristics of eggs detected in feces of the llama by centrifugal flotation in sugar solution (specific gravity: 1.30), development of third-stage larvae within the eggs after incubation of the llama feces at room temperature for ≥30 days, and the morphology of third-stage larvae released from the embryonated eggs. Collectively, these findings indicate that the llama, born and raised in Oregon, harbored an autochthonous L. chavezi infection. Eggs identified as L. chavezi were also detected by centrifugal flotation of pelleted feces from 3 of 7 herd mates of the llama indicating this parasite is endemic in the Oregon herd. The findings reported herein serve to alert diagnosticians and veterinary practitioners to the occurrence of L. chavezi in New World camelids in the United States and describe diagnostic features of this potential pathogen.

A New World of Knowledge: Canadian Universities and ...

International Development Research Centre (IDRC) Digital Library (Canada)

A New World of Knowledge examines how globalization has obliged universities in Canada to reassess and rethink the international dimension of their mission and practice. All now include an international dimension in their mission statement. Is this a true statement of educational principles? Or is it simply a marketing ...

The world food situation: New driving forces and required actions [In Chinese

OpenAIRE

von Braun, Joachim

2008-01-01

"The world food situation is currently being rapidly redefined by new driving forces. Income growth, climate change, high energy prices, globalization, and urbanization are transforming food consumption, production, and markets. The influence of the private sector in the world food system, especially the leverage of food retailers, is also rapidly increasing. Changes in food availability, rising commodity prices, and new producer–consumer linkages have crucial implications for the livelihoods...

New idea on the classification of world super-large deposits

International Nuclear Information System (INIS)

Tong Hangshou

2012-01-01

According to the theory of 'multi factors and compound genesis', 'complexity of mineralization' and 'metallogenic series', this paper proposed a new classification idea on the world super-large deposits with the combination of new results on the study of global background for super-large deposits and the model of 'conjugation of multi-source and focus of multi-factors'. 15 super-large deposits with the reserve over 50000 t were studied as the ases, 6 types and 13 sub-types of economics-genesis have been divided for the super-large deposit. The classification is discoursed with symbols and worlds and brief introduction on typical deposit. (authors)

The World Nuclear University: New partnership in nuclear education

International Nuclear Information System (INIS)

2007-07-01

The important role which the IAEA plays in assisting Member States in the preservation and enhancement of nuclear knowledge and in facilitating international collaboration in this area has been recognized by the General Conference of the International Atomic Energy Agency in resolutions GC(46)/RES/11B, GC(47)/RES/10B, GC(48)/RES/13 and GC(50)/RES/13. A continued focus of IAEA activities in managing nuclear knowledge is to support Member States to secure and sustain human resources for the nuclear sector, comprising both the replacement of retiring staff and building of new capacity. The IAEA assists Member States, particularly developing ones, in their efforts to sustain nuclear education and training in all areas of nuclear technology for peaceful purposes, which is a necessary prerequisite for succession planning, in particular through the networking of nuclear education and training, including activities of the World Nuclear University (WNU) and the Asian Network for Education in Nuclear Technology (ANENT). The report on the attached CD-ROM, The World Nuclear University: New Partnership in Nuclear Education, gives an overview of the history of the development of the World Nuclear University and related IAEA activities and contains an analysis and recommendations from the first WNU Summer Institute, held in 2005 in the USA

A New World Energy Order is coming. Energy debate

International Nuclear Information System (INIS)

Odell, P.; Guillet, J.; Birol, F.; Kramer, M.; Van Gool, M.

2007-01-01

Peter Odell, Professor Emeritus of International Energy Studies of Erasmus University Rotterdam, Netherlands, recently wrote a remarkably succinct and provocative paper in which he described his vision of the new world energy order that is on the way in the form of eight propositions. The editors of this new magazine asked three experienced energy analysts as well as the CEO of a major energy company, the Dutch gas producer Gasunie, for a response

A complete mitochondrial genome sequence of the wild two-humped camel (Camelus bactrianus ferus: an evolutionary history of camelidae

Directory of Open Access Journals (Sweden)

Meng He

2007-07-01

Full Text Available Abstract Background The family Camelidae that evolved in North America during the Eocene survived with two distinct tribes, Camelini and Lamini. To investigate the evolutionary relationship between them and to further understand the evolutionary history of this family, we determined the complete mitochondrial genome sequence of the wild two-humped camel (Camelus bactrianus ferus, the only wild survivor of the Old World camel. Results The mitochondrial genome sequence (16,680 bp from C. bactrianus ferus contains 13 protein-coding, two rRNA, and 22 tRNA genes as well as a typical control region; this basic structure is shared by all metazoan mitochondrial genomes. Its protein-coding region exhibits codon usage common to all mammals and possesses the three cryptic stop codons shared by all vertebrates. C. bactrianus ferus together with the rest of mammalian species do not share a triplet nucleotide insertion (GCC that encodes a proline residue found only in the nd1 gene of the New World camelid Lama pacos. This lineage-specific insertion in the L. pacos mtDNA occurred after the split between the Old and New World camelids suggests that it may have functional implication since a proline insertion in a protein backbone usually alters protein conformation significantly, and nd1 gene has not been seen as polymorphic as the rest of ND family genes among camelids. Our phylogenetic study based on complete mitochondrial genomes excluding the control region suggested that the divergence of the two tribes may occur in the early Miocene; it is much earlier than what was deduced from the fossil record (11 million years. An evolutionary history reconstructed for the family Camelidae based on cytb sequences suggested that the split of bactrian camel and dromedary may have occurred in North America before the tribe Camelini migrated from North America to Asia. Conclusion Molecular clock analysis of complete mitochondrial genomes from C. bactrianus ferus and L

Bluetongue disease and seroprevalence in South American camelids from the northwestern region of the United States.

Science.gov (United States)

Allen, Andrew J; Stanton, James B; Evermann, James F; Fry, Lindsay M; Ackerman, Melissa G; Barrington, George M

2015-03-01

In late summer/early fall of 2013, 2 South American camelids from central Washington were diagnosed with fatal bluetongue viral disease, an event which is rarely reported. A 9-year-old intact male llama (Lama glama), with a 1-day history of anorexia, recumbency, and dyspnea before death. Abundant foam discharged from the mouth and nostrils, and the lungs were severely edematous on postmortem examination. Histologically, there was abundant intra-alveolar edema with fibrin. Hemorrhage and edema disrupted several other organs. Bluetongue viral RNA was detected by reverse transcription polymerase chain reaction (RT-PCR), and serotype 11 was identified by sequencing a segment of the VP2 outer capsid gene. Approximately 1 month later, at a site 150 miles north of the index case, a 2-year-old female alpaca with similar, acutely progressive clinical signs was reported. A postmortem examination was performed, and histologic lesions from the alpaca were similar to those of the llama, and again serotype 11 was detected by PCR. The occurrence of bluetongue viral infection and disease is described in the context of seasonal Bluetongue virus activity within the northwestern United States and southwestern Canada. © 2015 The Author(s).

World Coal Institute under new leadership

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-04-01

For the first time in its 20 year history the WCI has selected an environmental expert as its new Chief Executive. Milton Catelin has a strong background in environmental policy and governance but is a coal industry outsider. The profile includes Mr Catelin's opinions as to meeting the world's future energy needs - with an array of resources - renewable energy, fossil fuels and possibly nuclear energy. He sees the UK as being in a good position to exploit carbon capture and storage. Mr Catelin sees his major task as persuading a sceptical public to view the contribution of the coal industry in its totality. 1 photo.

Canine leishmaniosis in the Old and New Worlds: unveiled similarities and differences.

Science.gov (United States)

Dantas-Torres, Filipe; Solano-Gallego, Laia; Baneth, Gad; Ribeiro, Vitor Marcio; de Paiva-Cavalcanti, Milena; Otranto, Domenico

2012-12-01

Canine leishmaniosis is a potentially life-threatening disease which is spreading geographically in the Old and New Worlds, where different diagnostic procedures, treatments, and control strategies are currently in place. This Opinion article outlines the similarities and differences between canine leishmaniosis in the Old and New Worlds, with emphasis on South America and Europe. Finally, it calls the attention of veterinary and public health authorities to standardize and improve practices for diagnosing, treating, and preventing the disease. Copyright © 2012 Elsevier Ltd. All rights reserved.

Camelid nanobodies used as crystallization chaperones for different constructs of PorM, a component of the type IX secretion system from Porphyromonas gingivalis.

Science.gov (United States)

Duhoo, Yoan; Roche, Jennifer; Trinh, Thi Trang Nhung; Desmyter, Aline; Gaubert, Anaïs; Kellenberger, Christine; Cambillau, Christian; Roussel, Alain; Leone, Philippe

2017-05-01

PorM is a membrane protein that is involved in the assembly of the type IX secretion system (T9SS) in Porphyromonas gingivalis, a major bacterial pathogen that is responsible for periodontal disease in humans. In the context of structural studies of PorM to better understand T9SS assembly, four camelid nanobodies were selected, produced and purified, and their specific interaction with the N-terminal or C-terminal part of the periplasmic domain of PorM was investigated. Diffracting crystals were also obtained, and the structures of the four nanobodies were solved by molecular replacement. Furthermore, two nanobodies were used as crystallization chaperones and turned out to be valuable tools in the structure-determination process of the periplasmic domain of PorM.

Capitalism and the New World Order of the 21st Century Age | Ugwu ...

African Journals Online (AJOL)

The Post-Cold War Capitalists'-based Vision here being called a 'New World Order', especially, in its current practices, as it has been imposed on the rest of the world by the G8 nations and assisted by the World Bank, IMF, United Nations, WTO and NATO, is a 21st Century Imperialist Rule constantly being communicated to ...

The dipteran family Celyphidae in the New World, with discussion of and key to world genera (Insecta, Diptera

Directory of Open Access Journals (Sweden)

Stephen D. Gaimari

2017-10-01

Full Text Available The family Celyphidae (Diptera, Lauxanioidea is verified as part of the New World fauna, with a second specimen discovered of a species described from French Guiana in 1844 by P.J.M. Macquart. As this species possesses characteristics that clearly suggest a separate lineage from the Old World celyphids, a new genus is proposed, Atopocelyphus gen. n., with the type species, Celyphus ruficollis Macquart, in the new combination Atopocelyphus ruficollis (Macquart, comb. n. A key to world genera of Celyphidae is presented, along with discussion of generic concepts. Chamaecelyphus Frey is synonymized under Spaniocelyphus Hendel, syn. n., resulting in the following 10 new combinations: Spaniocelyphus africanus (Walker, comb. n.; S. dichrous (Bezzi, comb. n.; S. gutta (Speiser, comb. n.; S. halticinus (Frey, comb. n.; S. kalongensis (Vanschuytbroek, comb. n.; S. ruwenzoriensis (Vanschuytbroek, comb. n.; S. straeleni (Vanschuytbroek, comb. n.; S. upembaensis (Vanschuytbroek, comb. n.; S. violaceus (Vanschuytbroek, comb. n.; S. vrydaghi (Vanschuytbroek, comb. n. The subgenera of Celyphus Dalman are elevated to genus rank, as Paracelyphus Bigot, stat. rev., and Hemiglobus Frey, stat. rev., resulting in the following 17 new and revised combinations: Hemiglobus cheni (Shi, comb. n.; H. eos (Frey, comb. n.; H. lacunosus Frey, comb. rev.; H. pellucidus Frey, comb. rev.; H. planitarsalis (Shi, comb. n.; H. porosus (Tenorio, comb. n.; H. pulchmaculatus (Liu & Yang, comb. n.; H. quadrimaculatus (Tenorio, comb. n.; H. resplendens Frey, comb. rev.; H. rugosus (Tenorio, comb. n.; H. testaceus (Malloch, comb. n.; H. trichoporis (Shi, comb. n.; H. unicolor Frey, comb. rev.; H. violaceus Chen, comb. rev.; Paracelyphus hyacinthus Bigot, comb. rev.; P. medogis (Shi, comb. n.; P. vittalis (Shi, comb. n.

Camelid-derived heavy-chain nanobody against Clostridium botulinum neurotoxin E in Pichia pastoris.

Science.gov (United States)

Baghban, Roghayyeh; Gargari, Seyed Latif Mousavi; Rajabibazl, Masoumeh; Nazarian, Shahram; Bakherad, Hamid

2016-01-01

Botulinum neurotoxins (BoNTs) result in severe and often fatal disease, botulism. Common remedial measures such as equine antitoxin and human botulism immunoglobulin in turn are problematic and time-consuming. Therefore, diagnosis and therapy of BoNTs are vital. The variable domain of heavy-chain antibodies (VHH) has unique features, such as the ability to identify and bind specifically to target epitopes and ease of production in bacteria and yeast. The Pichia pastoris is suitable for expression of recombinant antibody fragments. Disulfide bond formation and correct folds of protein with a high yield are some of the advantages of this eukaryotic host. In this study, we have expressed and purified the camelid VHH against BoNT/E in P. pastoris. The final yield of P. pastoris-expressed antibody was estimated to be 16 mg/l, which is higher than that expressed by Escherichia coli. The nanobody expressed in P. pastoris neutralized 4LD50 of the BoNT/E upon i.p. injection in 25% of mice. The nanobody expressed in E. coli extended the mice's survival to 1.5-fold compared to the control. This experiment indicated that the quality of expressed protein in the yeast is superior to that of the bacterial expression. Favorable protein folding by P. pastoris seems to play a role in its better toxin-binding property. © 2014 International Union of Biochemistry and Molecular Biology, Inc.

Fungal Glucosylceramide-Specific Camelid Single Domain Antibodies Are Characterized by Broad Spectrum Antifungal Activity

Directory of Open Access Journals (Sweden)

Barbara De Coninck

2017-06-01

Full Text Available Chemical crop protection is widely used to control plant diseases. However, the adverse effects of pesticide use on human health and environment, resistance development and the impact of regulatory requirements on the crop protection market urges the agrochemical industry to explore innovative and alternative approaches. In that context, we demonstrate here the potential of camelid single domain antibodies (VHHs generated against fungal glucosylceramides (fGlcCer, important pathogenicity factors. To this end, llamas were immunized with purified fGlcCer and a mixture of mycelium and spores of the fungus Botrytis cinerea, one of the most important plant pathogenic fungi. The llama immune repertoire was subsequently cloned in a phage display vector to generate a library with a diversity of at least 108 different clones. This library was incubated with fGlcCer to identify phages that bind to fGlcCer, and VHHs that specifically bound fGlcCer but not mammalian or plant-derived GlcCer were selected. They were shown to inhibit the growth of B. cinerea in vitro, with VHH 41D01 having the highest antifungal activity. Moreover, VHH 41D01 could reduce disease symptoms induced by B. cinerea when sprayed on tomato leaves. Based on all these data, anti-fGlcCer VHHs show the potential to be used as an alternative approach to combat fungal plant diseases.

The new competition in the world market for nuclear reactors

International Nuclear Information System (INIS)

Finon, Dominique

2014-01-01

The current revival in the world market for nuclear reactors, notwithstanding Fukushima, completes the re-composition of the world's nuclear industry that started in the early 1990's and which has displaced nuclear power's centre of gravity towards Asia. In this new context, the capability to provide full-fledged financing for the buyers and to set up consortia that may include the operator have become major advantages at this stage, relegating to a lower order the ability to supply reactors with a high level of safety. (author)

To understand the new world of energy - Energy saving and energy efficiency: the world of energy 2.0

International Nuclear Information System (INIS)

Maestroni, Myriam; Chevalier, J.M.; Derdevet, Michel

2013-01-01

This bibliographical note contains the table of contents and a brief presentation of a book which proposes a general overview of the world of modern energy, focuses on the main associated political and climatic stakes and challenges. It also addresses the crucial issue of energy efficiency and energy savings which are the pillars of the current energy transition. The chapters address the world energy stakes and challenges, the emergence of a new energetic paradigm, the issues of energy efficiency and energy savings, the main sources of energy savings to be exploited and valorised, the situation in Europe and in the World regarding energy efficiency, the relationship between energy transition and local territories, the necessary continuous innovation

New trends in accident prevention due to the changing world of work

NARCIS (Netherlands)

Beeck, R. op de; Heuverswyn, K. van; Lemkowitz, S.; Saari, J.; Sundström-Frisk, C.; Zwetsloot, G.

2002-01-01

Changes in the world of work can give rise to new risk areas or they can change the way that occupational safety and health needs to be managed. This has implications for workplaces themselves and also for the occupational safety and health system. For this reason the 'changing world of work' has

DRESSING THE NEW WORLD. A Marie Sklodowska-Curie Research Fellowship

OpenAIRE

Thepaut-Cabasset, Corinne

2017-01-01

“Dressing the New World” aims to understand in detail the trade mechanism of European products and fashion overseas. It will evaluate the impact of European commodities and fashionable goods in everyday life in the colonial system. In particular it will study textiles and fashionable items in the Spanish New World, governed by the Spanish from Mexico City since the conquest of the Aztec Empire in 1521.

World Tax Index: New Methodology for OECD Countries, 2000-2010

OpenAIRE

Zuzana Machova; Igor Kotlan

2013-01-01

This paper follows our previous article, Kotlán and Machová (2012a), which presented an indicator of the tax burden that can be used as an alternative to the tax quota, or for implicit tax rates in macroeconomic analyses. This alternative is an overall multi-criteria index called the WTI – the World Tax Index. The aim of this paper is to present the new World Tax Index 2013 and its methodology, which allowed us to compute it for all 34 OECD countries for the 2000–2012 period, with special ref...

ELT in a changing world innovative approaches to new challenges

CERN Document Server

Ahmed, Azra; Saleem, Faiza; Cane, Graeme

2013-01-01

A novel ELT resource for language specialists and teachers across the world, this selection of papers is a collection of the most compelling and innovative ideas presented at a seminar hosted by the Centre of English Language, Aga Khan University, Pakistan, in January 2011, entitled 'ELT in a Changing World: Innovative Approaches to New Challenges'.The book is divided into three sections, the first of which is 'Global change and language learning'. This section offers a guided tour of language teaching evolution, highlighting the merits of enhanced language awareness, self-immersive and input/

Eradication of New World Screwworm from Jamaica

International Nuclear Information System (INIS)

2003-01-01

The New World Screwworm (NWS) is an insect pest affecting warm-blooded animals and also humans. It causes widespread economic losses in livestock production as well as pain and suffering to animals and to those people unfortunate enough to become infected. Although it is endemic in Jamaica, the screwworm can be eradicated from the island using the well proven and successful Sterile Insect Technique. In collaboration with the Jamaican authorities, the Department of Technical Co-operation of the IAEA is planning to sponsor a Model Project to eradicate screwworm from Jamaica. (IAEA)

Confronting the Digital Divide: Debunking Brave New World Discourses

Science.gov (United States)

Rowsell, Jennifer; Morrell, Ernest; Alvermann, Donna E.

2017-01-01

There is far more to the digital divide than meets the eye. In this article, the authors consolidate existing research on the digital divide to offer some tangible ways for educators to bridge the gap between the haves and have-nots, or the cans and cannots. Drawing on Aldous Huxley's notion of a "brave new world," some digital divide…

[The social status of women. For a new world order].

Science.gov (United States)

Gauffenic, A

1985-01-01

Curiosity about the place of women in development and solidarity with women's organizations in different economies prompt consideration of the individual and collective possibilities for women in public life and of the social status of women. Recent histories of Third World countries as reported in UN conferences held in Tunisia, Portugal, and New Delhi in 1982-83 and Western experience are the basis for identification of constraints in the development of women's movements and alternatives for participation of women in a new world order. Women have always contributed to the life and economic development of their countries, often in activities not recognized as economic, but they are excluded from processes of institutionalization and their presence is very rare at the highest levels of the social hierarchy. Women organized themselves and participated in the liberation movements of India, Malaysia, Libya, and Egypt, but were later relegated to their customary low status. Among the structural and ideological factors impeding access of women to political power and a true social status are cultural nationalism and religious ideology. Socialization is 1 of the processes by which members of a society acquire a common fund of knowledge, but norms produced by the dominant ideology, in this case male, pose a problem to dominated groups concerning the nature of their particularity. Such groups can strive for integration at the price of risking loss of identity, or they can contest the rules, situating themselves at the margin of the "laws" or rules. The essential question concerns the possibility of women rethinking the process and contents of socialization. A new system is required of perceptions, evaluations, and actions founded on new human values. In this perspective the women's movement would contribute to the realization of a new world order. Theories of equality, to comprehend reality in its entirety, must include equality while developing the concept of differences

Time for a New Agenda: Organizational Development in a Changing world with much Disruption

DEFF Research Database (Denmark)

Sørensen, Henrik B.

2017-01-01

organizations neglect to support a disruptive strategy. By demonstrating the existence of another development path, this paper attempts, from a theoretical point of view, to give a new and a more nuanced perspective on organizational development in a disruptive world. This new path is supportive in a disruptive......Abstract – Traditional organizational theory tends to point out that organizational development follows a certain pattern where the structure of the company is said to become ever more bureaucratic. However, in a world where all companies and industries are faced with disruption, bureaucratic...... world. The aim of the paper is to answer the following research question: How can companies manage processes of organizational development and structures to avoid the bureaucracy and potential crises of the traditional approach in a disruptive world? This research question is important because...

Geopolitics of petroleum. A new market. New risks. New worlds

International Nuclear Information System (INIS)

Lestrange, C. de; Paillard, Ch.A.; Zelenko, P.

2005-02-01

The aim of this book is to shade light on a complex world in complete evolution, the stakes of which for today's societies being proportional to the energy and economical importance of petroleum. The big petroleum fear of consuming countries and the reactions linked with oil shocks are now old stories. The producing countries are today at least as vulnerable to price variations and fluxes restrictions as the consumers of developed countries. Two countries, USA and Saudi Arabia, and one organisation, the OPEC, play a key role in the regulation of this system, the equilibrium of which is now threatened by the reinforcement of preoccupations like environment and human rights protection. New challenges occur: the increase of demand, the concentration of offer, some technological changes that would limit the petroleum needs in the future, and the increasing insecurity of key oil-producing regions. At a shorter term, the geopolitical context of Middle-East is the most worrying. (J.S.)

Maintenance of syntenic groups between Cathartidae and Gallus gallus indicates symplesiomorphic karyotypes in new world vultures

Directory of Open Access Journals (Sweden)

Marcella M. Tagliarini

2011-01-01

Full Text Available Similarities between New World and Old World vultures have been interpreted to reflect a close relationship and to suggest the inclusion of both in Accipitridae (Falconiformes. However, deeper analyses indicated that the placement of the New World vultures (cathartids in this Order is uncertain. Chromosome analysis has shown that cathartids retained a karyotype similar to the putative avian ancestor. In order to verify the occurrence of intrachromosomal rearrangements in cathartids, we hybridized whole chromosome probes of two species (Gallus gallus and Leucopternis albicollis onto metaphases of Cathartes aura. The results showed that not only were the syntenic groups conserved between Gallus and C. aura, but probably also the general gene order, suggesting that New World vultures share chromosomal symplesiomorphies with most bird lineages.

Latitude, elevational climatic zonation and speciation in New World vertebrates

DEFF Research Database (Denmark)

Cadena, Carlos Daniel; Kozak, Kenneth H.; Gomez, Juan Pablo

2012-01-01

in tropical versus temperate areas. Here, we quantify overlap in the climatic distributions of 93 pairs of sister species of mammals, birds, amphibians and reptiles restricted to either the New World tropics or to the Northern temperate zone. We show that elevational ranges of tropical- and temperate...

Humoral response to 2 inactivated bluetongue virus serotype-8 vaccines in South American camelids.

Science.gov (United States)

Zanolari, P; Bruckner, L; Fricker, R; Kaufmann, C; Mudry, M; Griot, C; Meylan, M

2010-01-01

Bluetongue virus serotype 8 (BTV-8) has caused disease in domestic ruminants in several countries of northern Europe since 2006. In 2008 a mass-vaccination program was launched in most affected countries using whole virus inactivated vaccines. To evaluate 2 inactivated vaccines (Bovilis BTV 8; BTVPUR AlSap8) for immunogenicity and safety against BTV-8 in South American camelids (SAC) in a field trial. Forty-two SAC (25 Alpacas, 17 Llamas) aged between 1 and 16 years. The animals were vaccinated twice at intervals of 21 days. They were observed clinically for adverse local, systemic, or both reactions throughout the trial. Blood samples collected on days 0, 14, 21, 43, and 156 after vaccination were tested for the presence of BTV-8 virus by real time-polymerase chain reaction and of specific antibodies by competitive ELISA and a serum neutralization test. All vaccinated animals developed antibodies to BTV-8 after the 2nd administration of the vaccine. No adverse effects were observed except for moderate local swellings at the injection site, which disappeared within 21 days. Slightly increased body temperatures were only observed in the first 2 days after vaccination. The BTV was not detected in any of the samples analyzed. The administration of the 2 inactivated commercial vaccines was safe and induced seroconversion against BTV-8 in all vaccinated animals. The results of this study suggest that 2 doses injected 3 weeks apart is a suitable vaccination regimen for SAC.

Diminished internalization and action of 1,25-dihydroxyvitamin D3 in dermal fibroblasts cultured from New World primates

International Nuclear Information System (INIS)

Adams, J.S.; Gacad, M.A.; Baker, A.J.; Kheun, G.; Rude, R.K.

1985-01-01

We investigated the occurrence of 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3]-resistant osteomalacia in the New World primate colony of Saguinus imperator at the Los Angeles Zoo. The mean serum concentration of 1,25-(OH)2D3 was elevated 5-fold in the New World primates compared to that in their Old World counterparts. The specific internalization of 0.6 nM [ 3 H]1,25-(OH)2D3 by cultured dermal fibroblasts from New World primates was reduced 75% compared to that by cells from Old World primates or man. The decrease in hormone uptake resulted from a decrease in the number of high affinity intracellular binding sites for 1,25-(OH)2D3 and apparently caused a 90-95% reduction in 1,25-(OH)2D3-induced 25-hydroxyvitamin-D3-24-hydroxylase activity. There was no alteration in the capacity or avidity of New World primate serum for 1,25-(OH)2D3 compared to that of serum from Old World primates. These data suggest that the occurrence of vitamin D-resistant osteomalacia in New World primates is the result of decreased high affinity, receptor-mediated uptake of 1,25-(OH)2D3 by the target cell

What Change Can The New Developments In Energy Sector Bring Into the World`s Energypolitical and Geopolitical Order?

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Onur TUTULMAZ

2014-12-01

Full Text Available The recent developments bring US to a leading natural gas and oil producer position. The attempts in last 20 years to bring new horizontal drilling and hydraulic fracturing technologies together have developed a success in shale gas and oil production in US; the production volumes has reached to a position to redefine the market. Last estimations are bringing more information about the shale capacities of the major basins of the world. However, the estimates are based on a wide range of assumptions and consequently their results vary in a large scale. In any case, these developments have crucial economic, political and geopolitical consequences on the energy market, petroleum producer and consumer countries and regions. Despite the wide range of ambiguity of the estimated size of the resources, the estimations show US and North America has one of the biggest potential, already turning technology into the giant production numbers. Some of the estimations allege so big numbers can even mean to a new world order. The asymmetric nature of the potential, can also be said, increases some of the expected impacts too. In this study, basically, we want to supply an initial solid and economical evaluation to this ambiguity. We are trying to shape a frame for the new energy potential and to put it in a place in the current practice of the world. Secondly, in this context, we are underlying here some of the possible economic and geopolitical consequences each of which can constitute a subject of deeper study.

Characterization of tobacco geminiviruses in the Old and New World.

Science.gov (United States)

Paximadis, M; Idris, A M; Torres-Jerez, I; Villarreal, A; Rey, M E; Brown, J K

1999-01-01

Biological differences and molecular variability between six phenotypically distinct tobacco-infecting geminivirus isolates from southern Africa (Zimbabwe) and Mexico were investigated. Host range studies conducted with tobacco virus isolates ZIM H from Zimbabwe and MEX 15 and MEX 32 from Mexico indicated all had narrow host ranges restricted to the Solanaceae. Alignment of coat protein gene (CP) and common region (CR) sequences obtained by PCR, and phylogenetic analysis of the CP sequences indicated Zimbabwean isolates were distantly related to those from Mexico and that geographically proximal isolates shared their closest affinities with Old and New World geminiviruses, respectively. Zimbabwean isolates formed a distinct cluster of closely related variants (> 98% sequence identity) of the same species, while MEX 15 segregated independently from MEX 32, the former constituting a distinct species among New World geminiviruses, and the latter being a variant, Texas pepper virus-Chiapas isolate (TPV-CPS) with 95% sequence identity to TPV-TAM. Results collectively indicated a geographic basis for phylogenetic relationships rather than a specific affiliation with tobacco as a natural host. MEX 15 is provisionally described as a new begomovirus, tobacco apical stunt virus, TbASV, whose closest CP relative is cabbage leaf curl virus, and ZIM isolates are provisionally designated as tobacco leaf curl virus, TbLCV-ZIM, a new Eastern Hemisphere begomovirus, which has as its closest relative, chayote mosaic virus from Nigeria.

THE NEW “UNIVERSAL TRUTH” OF THE WORLD WIDE WEB

OpenAIRE

Alexandru Tăbușcă

2011-01-01

We all see that the world wide web is permanently evolving and developing. New websites are created continuously and push the limits of the old HTML specs in all respects. HTML4 is the real standard for almost 10 years and developers are starting to look for new and improved technologies to help them provide greater functionality. In order to give the authors flexibility and interoperability and to enable much more interactive and innovative websites and applications, HTML5 introduces and enh...

New information on world uranium resource, production, supply and demand

International Nuclear Information System (INIS)

Zhang Jianguo; Meng Jin

2006-01-01

New information on world uranium resource, production, supply and demand is introduced. Up to now, explored uranium resources at production cost < USD 40/kg U has 2523257 t uranium; production cost < USD 80/kg U has 5911514 t uranium; production cost < USD130/kg U has 11280488 t uranium; and cost range unassigned has 3102000 t uranium. At moment, the demand uranium of each year is about 67000 t U. After 2020, world uranium demand will rise well above 100000 t per annum with sharp revival of nuclear power plants. With three kinds of economic growth the cumulative requirement of the uranium in low demand case, middle demand case and high demand case from 2000 to 2050 is 3390000, 5394100 and 7577300 t respectively. In the world market uranium price rises from 20 years lowest 18.2 USD/kg U to 75.4 USD/kg U. In 2003, global uranium product is about 35385 t U, and 2004, global uranium product is about 40475 t U. In 2004's world uranium production underground mining, open pit, in situ, by product, and combination account for 39%, 27%, 19%, 11% and 4% respectively. (authors)

D-brane. Superstrings and new perspective of our world

Energy Technology Data Exchange (ETDEWEB)

Hashimoto, Koji [RIKEN, Saitama, Wako (Japan). Mathematical Physics Lab.

2012-07-01

Superstring theory is a promising theory which can potentially unify all the forces and the matters in particle physics. A new multi-dimensional object which is called ''D-brane'' was found. It drastically changed our perspective of a unified world. We may live on membrane-like hypersurfaces in higher dimensions (''braneworld scenario''), or we can create blackholes at particle accelerators, or the dynamics of quarks is shown to be equivalent to the higher dimensional gravity theory. All these scenarios are explained in this book with plain words but with little use of equations and with many figures. The book starts with a summary of long-standing problems in elementary particle physics and explains the D-branes and many applications of them. It ends with future roads for a unified ultimate theory of our world. (orig.)

Global Civil Society: the Formation of the New Actor of World Politics. Part I

Directory of Open Access Journals (Sweden)

Владимир Геннадьевич Иванов

2010-12-01

Full Text Available The article is dedicated to the analysis of the emerging global phenomenon: the rise of global civil society as the new actor of world politics. The author suggests that the importance of global civil society as a «third way» between the State and the Free Market is especially high at the time of modern economic crisis. Global civil society organizations work out the new socio-political agenda for the world and new approaches to the global problems. This shaping society is full of conflicts and contradictions but its rapid development in the 1990-2000th is the milestone for developing of truly global politics.

Mummification in the Ancient and New World.

Science.gov (United States)

Rosso, Ana Maria

2014-01-01

In the Ancient and New World there was a custom to preserve the corpse in a natural and artificial way. Since Paleolithic man believed in an afterlife and even in Mesoamerica and the Andes cultures, care and ceremony were practiced to the burial of the dead in an ancestral cult. Mortuary rituals were developed in Pre-dynastic Egypt (4500-3100 BC) but apparently they had begun before in America, c. 5000 BC. Mummies served for assisting the soul to survive and for preventing the dead from frightening the livings. Incas arrived at a point of perfection in these practices after other Andean cultures but we should not forget their older predecessors, the Chinchorro culture on the arid coast of the Atacama Desert. Different steps in the technique can be distinguished in both worlds: natural desiccation covered by animal skins, methods to protect the body skin and flesh removal, replacement with clay; black, red or mud-coated corpses, evisceration, body cavity treatment, cleansing and anointing the interior, brain removal, mummified bodies, corpses covered with natron, before being washed and bandaged or wrapped. It will be necessary to carefully check dates, techniques and periods in the two zones to establish exactly the evolution of the methods applied.

China's new oil import status underpins world's most dynamic petroleum scene

International Nuclear Information System (INIS)

Anon.

1994-01-01

China is poised to become a net importer of oil in 1994--95. That sets the stage for China importing more than 1 million b/d of crude oil and refined products on a net basis by the turn of the century. That development underpins a bigger story -- arguably the biggest story on the petroleum scene today. The turnabout that is seeing the world's fifth biggest oil producer go from significant oil exporter in recent years to major oil importer by the turn of the century points to several other truisms in the petroleum industry: That an oil demand surge in the Asia-Pacific region led by China will fuel overall world oil demand growth for years to come; that a refining and petrochemical boom in a country that accounts for about one fifth of the world's population has dramatic implications for those two industries; that privatization has gathered so much momentum in the global petroleum industry that even Communist China has embraced some form of it; that China's domestic crude supply shortfall is creating unprecedented opportunities for foreign upstream investors in one of the world's most prospective yet underexplored and underexploited regions; and that the same new openness that is distinguishing China's petroleum industry today is turning some of its state owned companies into major competitors to be reckoned with on the international scene, upstream and downstream. The paper discusses China's oil export/import balance, supply/demand outlook, policy changes, and new regulations governing export of crude oil and products

Initial Progress in Developing the New ICSU World Data System

Science.gov (United States)

Minster, J. H.; Capitaine, N.; Clark, D. M.; Mokrane, M.

2009-12-01

On October 24, 2008, at the 29th International Council for Science (ICSU) General Assembly in Maputo, Mozambique, a decision to form a new ICSU World Data System (WDS) was taken. The new ICSU World Data System (WDS) will replace the framework within which the current ICSU World Data Centers (WDCs) and services of the Federation of Astronomical and Geophysical data-analysis Services (FAGS) are currently organized. The transition from the old organizations to the new WDS was facilitated by the ICSU ad-hoc WDS Transition Team which developed a white paper with recommendations for the new WDS Scientific Committee (WDS-SC). The WDS-SC was appointed by ICSU and reports to the Executive Board and the General Assembly of ICSU. The WDSSC met for the first time in October 2009. WDS-SC shall be the governing body of WDS with the following tasks: 1) to ensure that the WDS clearly supports ICSU’s mission and objectives by ensuring the long-term stewardship and provision of quality-assessed data and data services to the international science community and other stakeholders; 2) to develop, and keep under continuous review, an implementation plan for the creation of the WDS by incorporating the ICSU WDCs, the Services of FAGS and a wide range of other data centers and services; 3) to define agreed standards, establish and oversee the procedures for the review and accreditation of existing and new facilities; 4) to monitor the geographic and disciplinary scope of the system and to develop strategies for the recruitment and establishment of new WDS facilities as necessary; 5) to consider resource issues and provide guidance on funding mechanisms for facilities within WDS when appropriate; 6) to develop strong cooperative links with the ICSU Strategic Coordinating Committee on Information and Data (SCCID);and 7) to cooperate closely with the ICSU Committee on Data for Science and Technology (CODATA). WDS development will proceed from these initial concepts: history and legacy of

Fauna, flora, fowl, and fruit: effects of the Columbian Exchange on the allergic response of New and Old World inhabitants.

Science.gov (United States)

Salvaggio, J E

1992-01-01

The Columbian Exchange has been described as "the most important event in human history since the end of the Ice Age." This interchange of many species of fauna, flora, fowl, and fruits resulted in new encounters between New and Old World inhabitants. Prominent among these were manifestations of allergic reactions to many of the new substances. Little imagination is required to reflect on what these substances, added to or detracted from both the New and Old World lifestyles, habits, and diets. The numerous peas, vegetable seeds, and grasses, such as sugarcane, introduced during Columbus' later voyages, made an enormous difference in the lives of New World inhabitants, as did the introduction of the cow and horse, not to mention substances such as coconuts and bananas, that are now intimately associated with the Caribbean and the Bahamas. This article focuses on some the more important exchange substances and emphasizes many forms of anaphylaxis: asthma, food allergy, hypersensitivity pneumonitis, chronic bronchitis, rhinitis, serum sickness, and other conditions that developed in both New and Old World inhabitants. To mention only a few examples, the Europeans introduced to the New World potential dangers such as honeybees (anaphylaxis). It also gave the New World the cow and the horse (serum sickness), which became the constant companion of Columbus' Indians and the American cowboy. It gave the Italians their thick red gravy, and the New World its pizza (food allergy). The Caribbean received bananas and coconuts and the New World embraced coffee (caffeine addiction). On the other hand, the exchange also caused Europeans to begin puffing away on tobacco.

Molecular phylogeny of microhylid frogs (Anura: Microhylidae) with emphasis on relationships among New World genera

Science.gov (United States)

2012-01-01

Background Over the last ten years we have seen great efforts focused on revising amphibian systematics. Phylogenetic reconstructions derived from DNA sequence data have played a central role in these revisionary studies but have typically under-sampled the diverse frog family Microhylidae. Here, we present a detailed phylogenetic study focused on expanding previous hypotheses of relationships within this cosmopolitan family. Specifically, we placed an emphasis on assessing relationships among New World genera and those taxa with uncertain phylogenetic affinities (i.e., incertae sedis). Results One mitochondrial and three nuclear genes (about 2.8 kb) were sequenced to assess phylogenetic relationships. We utilized an unprecedented sampling of 200 microhylid taxa representing 91% of currently recognized subfamilies and 95% of New World genera. Our analyses do not fully resolve relationships among subfamilies supporting previous studies that have suggested a rapid early diversification of this clade. We observed a close relationship between Synapturanus and Otophryne of the subfamily Otophryninae. Within the subfamily Gastrophryninae relationships between genera were well resolved. Conclusion Otophryninae is distantly related to all other New World microhylids that were recovered as a monophyletic group, Gastrophryninae. Within Gastrophryninae, five genera were recovered as non-monophyletic; we propose taxonomic re-arrangements to render all genera monophyletic. This hypothesis of relationships and updated classification for New World microhylids may serve as a guide to better understand the evolutionary history of this group that is apparently subject to convergent morphological evolution and chromosome reduction. Based on a divergence analysis calibrated with hypotheses from previous studies and fossil data, it appears that microhylid genera inhabiting the New World originated during a period of gradual cooling from the late Oligocene to mid Miocene. PMID:23228209

Molecular phylogeny of microhylid frogs (Anura: Microhylidae) with emphasis on relationships among New World genera.

Science.gov (United States)

de Sá, Rafael O; Streicher, Jeffrey W; Sekonyela, Relebohile; Forlani, Mauricio C; Loader, Simon P; Greenbaum, Eli; Richards, Stephen; Haddad, Célio F B

2012-12-10

Over the last ten years we have seen great efforts focused on revising amphibian systematics. Phylogenetic reconstructions derived from DNA sequence data have played a central role in these revisionary studies but have typically under-sampled the diverse frog family Microhylidae. Here, we present a detailed phylogenetic study focused on expanding previous hypotheses of relationships within this cosmopolitan family. Specifically, we placed an emphasis on assessing relationships among New World genera and those taxa with uncertain phylogenetic affinities (i.e., incertae sedis). One mitochondrial and three nuclear genes (about 2.8 kb) were sequenced to assess phylogenetic relationships. We utilized an unprecedented sampling of 200 microhylid taxa representing 91% of currently recognized subfamilies and 95% of New World genera. Our analyses do not fully resolve relationships among subfamilies supporting previous studies that have suggested a rapid early diversification of this clade. We observed a close relationship between Synapturanus and Otophryne of the subfamily Otophryninae. Within the subfamily Gastrophryninae relationships between genera were well resolved. Otophryninae is distantly related to all other New World microhylids that were recovered as a monophyletic group, Gastrophryninae. Within Gastrophryninae, five genera were recovered as non-monophyletic; we propose taxonomic re-arrangements to render all genera monophyletic. This hypothesis of relationships and updated classification for New World microhylids may serve as a guide to better understand the evolutionary history of this group that is apparently subject to convergent morphological evolution and chromosome reduction. Based on a divergence analysis calibrated with hypotheses from previous studies and fossil data, it appears that microhylid genera inhabiting the New World originated during a period of gradual cooling from the late Oligocene to mid Miocene.

World new facilities for radioactive isotope beams

International Nuclear Information System (INIS)

Motobayashi, T.

2014-01-01

The use of unstable nuclei in the form of energetic beams for nuclear physics studies is now entering into a new era. 'New-generation' facilities are either in operation, under construction or being planned. They are designed to provide radioactive isotope (RI) beams with very high intensities over a wide range of nuclides. These facilities are expected to provide opportunities to study nuclear structure, astrophysical nuclear processes and nuclear matter with large proton-neutron imbalance in grate detail. This article reports on the current status of such new-generation RI-beam facilities around the world. In order to cover different energy domains and to meet various scientific demands, the designs of RI-beam facilities are of a wide variety. For example, RIBF in Japan, FAIR in Germany and FRIB in US are based on the fragmentation scheme for beams with energies of a few hundred MeV/nucleon to GeV/nucleon, whereas Spiral2 in France, SPES in Italy, HIE-ISOLDE in Switzerland/France, and the future facility EURISOL in Europe are based on the ISOL method, and aim at providing lower-energy RI beams. There are a many other projects including upgrades of existing facilities in the three continents, America, Asia and Europe

"The New World". Musica e narratività nel cinema di Terrence Malick

Directory of Open Access Journals (Sweden)

Francesco Finocchiaro

2011-04-01

Full Text Available The New World (USA, 2005 is the fourth full-length film’s title of the American director Terrence Malick. The movie tells the legendary love story between Princess Pocahontas (Q’orianka Kilcher of the Powathan tribe and the English soldier and explorer John Smith (Colin Farrell. The background of the historical events concerns the foundation of one of the first European settlements in the New World, at the close beginning of 17th Century. The specific topic of the proposed didactical unit, which is addressed to a 2nd or 3rd class of the Secondary School, consists in the analysis of some film sequences, that all employ the main theme of the second movement (Adagio from the Wolfgang Amadeus Mozart’s Piano Concerto K 488. The didactic unit is based on an audiovisual analysis, that focuses on developing some categories, concepts and tools, which can enrich the reading strategies of a kind of text – the syncretic cinematographic one – with a central role in the contemporary music production and consumption. Malick’s work not only represents a polished example of music employment in a movie, but also deals with a topic of a relevant historical importance, that is the encounter between the Old and New World; indeed this topic is particularly suitable for encouraging a reflection upon cultural diversity and interethnic communication.

Nuclear weapons proliferation and the new world order

International Nuclear Information System (INIS)

Krause, J.

1994-01-01

The proliferation of nuclear weapons has become the priority safety problem since the end of the cold war. The danger that new nuclear states may arise from the former Soviet Union, the limited effectiveness of existing control systems, the increased attractiveness of nuclear weapons for countries in which a 'safety vacuum' has developed since the withdrawal of American and Russian forces, as well as the danger that additional nuclear states (China, India, Pakistan) may become unstable or disintegrate, make it necessary to explore and show the ensuing risks. The study contains analyses from well-respected experts from Germany, Russia, Japan and the USA. They show how the changes in regional security situations could lead to nuclear risks under certain circumstances, and the likely international consequences. A second point of emphasis consens the feasibility of new approaches or instruments in international non-proliferatic policy. New possibilities for the improvement of excisting control systems and the extension of international consensus on an intensification of the non-proliferation regime are offered by the changes in world politics. (orig.) [de

Invisible woman: female slavery in the New World

Directory of Open Access Journals (Sweden)

Marion Rust

1992-01-01

Full Text Available [First paragraph] Slave women in Caribbean society, 1650-1838, by BARBARA BUSH. Bloomington: Indiana University Press, 1990. xiii + 190 pp. (Cloth US$ 29.95, Paper US$ 12.50 [Published simultaneously by: James Curry, London, & Heinemann Publishers (Caribbean, Kingston.] Within the plantation household: Black and White women of the Old South, by ELIZABETH FOX-GENOVESE. Chapel Hill: University of North Carolina Press, 1988. xvii + 544 pp. (Cloth US$ 34.95, Paper US$ 12.95 Slave women in the New World: gender stratiftcation in the Caribbean, by MARIETTA MORRISSEY. Lawrence: University Press of Kansas, 1989. xiv + 202 pp. (Cloth US$ 29.95 In a letter to his son in 1760, Chesapeake slaveowner Charles Carrol employed a curious euphemism for woman: "fair sex." Obviously, he wasn't thinking of his slaves. An attempt to remedy his negligence by considering this popular definition of eighteenth-century womanhood in relation to the females he forgot reveals this highly restrictive code to be exclusionary as well, for the difficulty of figuring out how brown or black skin can be "fair" suggests that a bondwoman in the New World was not, according to dominant ideology, a woman. Slavery made nonsense of female gender in the case of those whose labor allo wed white society its definition. A contemporary observer reveals just how thorough was the distinction between white womanly passivity and whatever unnamed oblivion was left to black females: "The labor of the slave thus becomes the substitute for that of the woman" (Smith 1980:70; Dew 1970 [1832]:36.

A New World of Mathematics Thinking

Science.gov (United States)

Schwartz, James E.

2010-01-01

The "flat" world described by Friedman (2006) is one of global supply chains and economic networks, outsourcing, international personal entrepreneurial opportunities, and nearly unlimited, universal information availability. American children will inherit a world in which their competition and opportunities are international. In light of these…

Molecular phylogeny of microhylid frogs (Anura: Microhylidae with emphasis on relationships among New World genera

Directory of Open Access Journals (Sweden)

de Sá Rafael O

2012-12-01

Full Text Available Abstract Background Over the last ten years we have seen great efforts focused on revising amphibian systematics. Phylogenetic reconstructions derived from DNA sequence data have played a central role in these revisionary studies but have typically under-sampled the diverse frog family Microhylidae. Here, we present a detailed phylogenetic study focused on expanding previous hypotheses of relationships within this cosmopolitan family. Specifically, we placed an emphasis on assessing relationships among New World genera and those taxa with uncertain phylogenetic affinities (i.e., incertae sedis. Results One mitochondrial and three nuclear genes (about 2.8 kb were sequenced to assess phylogenetic relationships. We utilized an unprecedented sampling of 200 microhylid taxa representing 91% of currently recognized subfamilies and 95% of New World genera. Our analyses do not fully resolve relationships among subfamilies supporting previous studies that have suggested a rapid early diversification of this clade. We observed a close relationship between Synapturanus and Otophryne of the subfamily Otophryninae. Within the subfamily Gastrophryninae relationships between genera were well resolved. Conclusion Otophryninae is distantly related to all other New World microhylids that were recovered as a monophyletic group, Gastrophryninae. Within Gastrophryninae, five genera were recovered as non-monophyletic; we propose taxonomic re-arrangements to render all genera monophyletic. This hypothesis of relationships and updated classification for New World microhylids may serve as a guide to better understand the evolutionary history of this group that is apparently subject to convergent morphological evolution and chromosome reduction. Based on a divergence analysis calibrated with hypotheses from previous studies and fossil data, it appears that microhylid genera inhabiting the New World originated during a period of gradual cooling from the late Oligocene to

World Heritage Sites through the Eyes of New Tourists – Who Cares about World Heritage Brand in Budapest?

Directory of Open Access Journals (Sweden)

Ivett Sziva

2017-03-01

Full Text Available Budapest is one the most emerging tourism destinations in Central-Eastern Europe, and besides the popularity of the regenerated “multicultural and design” district, its cultural heritage, particularly those on the list of the UNESCO World Heritage, assure its growing attractiveness. However the cultural sites are the most visited sightseeing attractions, our proposition was that the tourists are not aware of the fact, that they are visiting UNESCO World Heritage Site (WHS. The main aim of the paper is to highlight the importance of the WHS in cultural tourism, and to introduce the significance of place branding in it. A structured content analysis were taken out to analyse the reviews of the Tripadvisor considering the attractions of Budapest, with the objective of crystallizing the main motivations and awareness of the tourists visiting the world heritage site of Budapest. Further on our objective was to analyse their satisfaction with interpretation, attraction, and visitor management issues. Then their overall experiences, development needs and ideas for the world heritage sites attracting cultural tourism were taken into consideration. Our presupposition was that new technologies can improve a site’s popularity by pulling the attention on its real values that can be experienced by the visitors.

'(World) risk society’ or ‘new rationalities of risk’?

DEFF Research Database (Denmark)

Rasborg, Klaus

2012-01-01

’. Moreover, Beck’s notions of second modernity, reflexivity, rationality and critique are critically examined. With the alternative positions discussed in the paper – represented by Jeffrey C. Alexander, Niklas Luhmann and Mitchell Dean – some indications are given as to how one might fruitfully elaborate...... on the problem of risk. Thus, rather than a mainly technology-driven new type of social reality, the ‘(world) risk society’ could perhaps better be seen as indicating a changing cultural self-understanding of late modern society, a new ‘semantics of crisis’, or the emergence of new forms of governmentality...... in the contemporary welfare state. In conclusion some indications are given as to how an analysis of more specific ‘risk logics’ or ‘rationalities’ could be elaborated on, and a terminology that reflects this more differentiated approach to risk in late modern society is suggested....

Maxwell: A new vision of the world

Science.gov (United States)

Maystre, Daniel

2014-05-01

The paper outlines the crucial contributions of James Clerk Maxwell to Physics and more generally to our vision of the world. He achieved 150 years ago a synthesis of the pioneering works in magnetostatics, electrostatics, induction and, by introducing the notion of displacement current, gave birth to Electromagnetics. Then, he deduced the existence of electromagnetic waves and identified light as one of them. Maxwell equations deeply changed a Newtonian conception of the world based on particle interactions by pointing out the vital role of waves in physics. This new conception had a strong influence on the development of quantum physics. Finally, the invariance of light velocity in Galilean frames led to Lorentz transformations, a key step toward the theory of relativity. Par ailleurs, les équations de Maxwell ont profondément changé une conception du monde newtonienne basée sur l'interaction entre particules en révélant le rôle essentiel des ondes en physique, ce qui eut une influence déterminante sur le développement de la physique quantique. Enfin, l'invariance de la vitesse de la lumière dans les repères galiléens a entraîné la découverte des transformations de Lorentz, une étape capitale vers la théorie de la relativité.

The genetic prehistory of the New World Arctic.

Science.gov (United States)

Raghavan, Maanasa; DeGiorgio, Michael; Albrechtsen, Anders; Moltke, Ida; Skoglund, Pontus; Korneliussen, Thorfinn S; Grønnow, Bjarne; Appelt, Martin; Gulløv, Hans Christian; Friesen, T Max; Fitzhugh, William; Malmström, Helena; Rasmussen, Simon; Olsen, Jesper; Melchior, Linea; Fuller, Benjamin T; Fahrni, Simon M; Stafford, Thomas; Grimes, Vaughan; Renouf, M A Priscilla; Cybulski, Jerome; Lynnerup, Niels; Lahr, Marta Mirazon; Britton, Kate; Knecht, Rick; Arneborg, Jette; Metspalu, Mait; Cornejo, Omar E; Malaspinas, Anna-Sapfo; Wang, Yong; Rasmussen, Morten; Raghavan, Vibha; Hansen, Thomas V O; Khusnutdinova, Elza; Pierre, Tracey; Dneprovsky, Kirill; Andreasen, Claus; Lange, Hans; Hayes, M Geoffrey; Coltrain, Joan; Spitsyn, Victor A; Götherström, Anders; Orlando, Ludovic; Kivisild, Toomas; Villems, Richard; Crawford, Michael H; Nielsen, Finn C; Dissing, Jørgen; Heinemeier, Jan; Meldgaard, Morten; Bustamante, Carlos; O'Rourke, Dennis H; Jakobsson, Mattias; Gilbert, M Thomas P; Nielsen, Rasmus; Willerslev, Eske

2014-08-29

The New World Arctic, the last region of the Americas to be populated by humans, has a relatively well-researched archaeology, but an understanding of its genetic history is lacking. We present genome-wide sequence data from ancient and present-day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia. We show that Paleo-Eskimos (~3000 BCE to 1300 CE) represent a migration pulse into the Americas independent of both Native American and Inuit expansions. Furthermore, the genetic continuity characterizing the Paleo-Eskimo period was interrupted by the arrival of a new population, representing the ancestors of present-day Inuit, with evidence of past gene flow between these lineages. Despite periodic abandonment of major Arctic regions, a single Paleo-Eskimo metapopulation likely survived in near-isolation for more than 4000 years, only to vanish around 700 years ago. Copyright © 2014, American Association for the Advancement of Science.

Inhibition of host extracellular signal-regulated kinase (ERK) activation decreases new world alphavirus multiplication in infected cells

Energy Technology Data Exchange (ETDEWEB)

Voss, Kelsey; Amaya, Moushimi [National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, 10650 Pyramid Place, Manassas, VA (United States); Mueller, Claudius [Center for Applied Proteomics and Personalized Medicine, George Mason University, 10900 University Boulevard, Manassas, VA (United States); Roberts, Brian [Leidos Health Life Sciences, 5202 Presidents Court, Suite 110, Frederick, MD (United States); Kehn-Hall, Kylene; Bailey, Charles [National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, 10650 Pyramid Place, Manassas, VA (United States); Petricoin, Emanuel [Center for Applied Proteomics and Personalized Medicine, George Mason University, 10900 University Boulevard, Manassas, VA (United States); Narayanan, Aarthi, E-mail: anaraya1@gmu.edu [National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, 10650 Pyramid Place, Manassas, VA (United States)

2014-11-15

New World alphaviruses belonging to the family Togaviridae are classified as emerging infectious agents and Category B select agents. Our study is focused on the role of the host extracellular signal-regulated kinase (ERK) in the infectious process of New World alphaviruses. Infection of human cells by Venezuelan equine encephalitis virus (VEEV) results in the activation of the ERK-signaling cascade. Inhibition of ERK1/2 by the small molecule inhibitor Ag-126 results in inhibition of viral multiplication. Ag-126-mediated inhibition of VEEV was due to potential effects on early and late stages of the infectious process. While expression of viral proteins was down-regulated in Ag-126 treated cells, we did not observe any influence of Ag-126 on the nuclear distribution of capsid. Finally, Ag-126 exerted a broad-spectrum inhibitory effect on New World alphavirus multiplication, thus indicating that the host kinase, ERK, is a broad-spectrum candidate for development of novel therapeutics against New World alphaviruses. - Highlights: • VEEV infection activated multiple components of the ERK signaling cascade. • Inhibition of ERK activation using Ag-126 inhibited VEEV multiplication. • Activation of ERK by Ceramide C6 increased infectious titers of TC-83. • Ag-126 inhibited virulent strains of all New World alphaviruses. • Ag-126 treatment increased percent survival of infected cells.

Inhibition of host extracellular signal-regulated kinase (ERK) activation decreases new world alphavirus multiplication in infected cells

International Nuclear Information System (INIS)

Voss, Kelsey; Amaya, Moushimi; Mueller, Claudius; Roberts, Brian; Kehn-Hall, Kylene; Bailey, Charles; Petricoin, Emanuel; Narayanan, Aarthi

2014-01-01

New World alphaviruses belonging to the family Togaviridae are classified as emerging infectious agents and Category B select agents. Our study is focused on the role of the host extracellular signal-regulated kinase (ERK) in the infectious process of New World alphaviruses. Infection of human cells by Venezuelan equine encephalitis virus (VEEV) results in the activation of the ERK-signaling cascade. Inhibition of ERK1/2 by the small molecule inhibitor Ag-126 results in inhibition of viral multiplication. Ag-126-mediated inhibition of VEEV was due to potential effects on early and late stages of the infectious process. While expression of viral proteins was down-regulated in Ag-126 treated cells, we did not observe any influence of Ag-126 on the nuclear distribution of capsid. Finally, Ag-126 exerted a broad-spectrum inhibitory effect on New World alphavirus multiplication, thus indicating that the host kinase, ERK, is a broad-spectrum candidate for development of novel therapeutics against New World alphaviruses. - Highlights: • VEEV infection activated multiple components of the ERK signaling cascade. • Inhibition of ERK activation using Ag-126 inhibited VEEV multiplication. • Activation of ERK by Ceramide C6 increased infectious titers of TC-83. • Ag-126 inhibited virulent strains of all New World alphaviruses. • Ag-126 treatment increased percent survival of infected cells

On the number of New World founders: a population genetic portrait of the peopling of the Americas.

Science.gov (United States)

Hey, Jody

2005-06-01

The founding of New World populations by Asian peoples is the focus of considerable archaeological and genetic research, and there persist important questions on when and how these events occurred. Genetic data offer great potential for the study of human population history, but there are significant challenges in discerning distinct demographic processes. A new method for the study of diverging populations was applied to questions on the founding and history of Amerind-speaking Native American populations. The model permits estimation of founding population sizes, changes in population size, time of population formation, and gene flow. Analyses of data from nine loci are consistent with the general portrait that has emerged from archaeological and other kinds of evidence. The estimated effective size of the founding population for the New World is fewer than 80 individuals, approximately 1% of the effective size of the estimated ancestral Asian population. By adding a splitting parameter to population divergence models it becomes possible to develop detailed portraits of human demographic history. Analyses of Asian and New World data support a model of a recent founding of the New World by a population of quite small effective size.

The testes transcriptome derived from the New World Screwworm, Cochliomyia hominivorax TSA

Science.gov (United States)

In a collaboration with National Center for Genome Resources researchers, we sequenced and assembled the testes transcriptome derived from the Pacora, Panama, production plant strain of the New World Screwworm, Cochliomyia hominivorax. This transcriptome contains 4,149 unigenes and the Transcriptome...

The World Needs a New Curriculum

Science.gov (United States)

Prensky, Marc

2014-01-01

The author proposes that today's existing, world-wide curriculum--based on offering roughly the same math, language arts, science, and social studies to all--is not what is required for the future, and is hurting rather than helping the world's students. Math, language arts, science, and social studies, he argues, are really "proxies"…

A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding

Energy Technology Data Exchange (ETDEWEB)

Yao, Guorui; Lam, Kwok-ho; Weisemann, Jasmin; Peng, Lisheng; Krez, Nadja; Perry, Kay; Shoemaker, Charles B.; Dong, Min; Rummel, Andreas; Jin, Rongsheng (BCH); (Cornell); (Tufts CTSI); (UCI); (MHH)

2017-08-07

Antibody treatment is currently the only available countermeasure for botulism, a fatal illness caused by flaccid paralysis of muscles due to botulinum neurotoxin (BoNT) intoxication. Among the seven major serotypes of BoNT/A-G, BoNT/A poses the most serious threat to humans because of its high potency and long duration of action. Prior to entering neurons and blocking neurotransmitter release, BoNT/A recognizes motoneurons via a dual-receptor binding process in which it engages both the neuron surface polysialoganglioside (PSG) and synaptic vesicle glycoprotein 2 (SV2). Previously, we identified a potent neutralizing antitoxin against BoNT/A1 termed ciA-C2, derived from a camelid heavy-chain-only antibody (VHH). In this study, we demonstrate that ciA-C2 prevents BoNT/A1 intoxication by inhibiting its binding to neuronal receptor SV2. Furthermore, we determined the crystal structure of ciA-C2 in complex with the receptor-binding domain of BoNT/A1 (HCA1) at 1.68 Å resolution. The structure revealed that ciA-C2 partially occupies the SV2-binding site on H_CA1, causing direct interference of HCA1 interaction with both the N-glycan and peptide-moiety of SV2. Interestingly, this neutralization mechanism is similar to that of a monoclonal antibody in clinical trials, despite that ciA-C2 is more than 10-times smaller. Taken together, these results enlighten our understanding of BoNT/A1 interactions with its neuronal receptor, and further demonstrate that inhibiting toxin binding to the host receptor is an efficient countermeasure strategy.

Eocene primates of South America and the African origins of New World monkeys

Science.gov (United States)

Bond, Mariano; Tejedor, Marcelo F.; Campbell, Kenneth E.; Chornogubsky, Laura; Novo, Nelson; Goin, Francisco

2015-04-01

The platyrrhine primates, or New World monkeys, are immigrant mammals whose fossil record comes from Tertiary and Quaternary sediments of South America and the Caribbean Greater Antilles. The time and place of platyrrhine origins are some of the most controversial issues in primate palaeontology, although an African Palaeogene ancestry has been presumed by most primatologists. Until now, the oldest fossil records of New World monkeys have come from Salla, Bolivia, and date to approximately 26 million years ago, or the Late Oligocene epoch. Here we report the discovery of new primates from the ?Late Eocene epoch of Amazonian Peru, which extends the fossil record of primates in South America back approximately 10 million years. The new specimens are important for understanding the origin and early evolution of modern platyrrhine primates because they bear little resemblance to any extinct or living South American primate, but they do bear striking resemblances to Eocene African anthropoids, and our phylogenetic analysis suggests a relationship with African taxa. The discovery of these new primates brings the first appearance datum of caviomorph rodents and primates in South America back into close correspondence, but raises new questions about the timing and means of arrival of these two mammalian groups.

The Chinese Dream-A New Dream Provided By China For The World

Institute of Scientific and Technical Information of China (English)

张保

2013-01-01

Along With promotion of comprehensive national strength, Chinese dream, as a new term ,begins to more and more popular. It is introduced, explained and spread by officials, scholars and medias. Would it be another dream for the world beside the American one?

Review of the New World Tigava lace bug complex (Hemiptera: Heteroptera: Tingidae), with the description of two new genera and two new species and a key to genera

Science.gov (United States)

The lace bug (Tingidae) genera belonging to the New World Tigava complex are reviewed. The two new genera and new species Mexicotingis brailovskyi, from Mexico, and Paraceratotingis convergens, from Venezuela, are described. Diagnoses, descriptions, and digital color photographs of the new taxa, d...

New Nuclear Fuel Disposition Opportunities in a Changed World

International Nuclear Information System (INIS)

Barrett, L.H.

2006-01-01

The world's economic, security, environmental, and technological situation has changed significantly in the last several years and these changes bring new opportunities for substantial policy improvements and redirections in the used nuclear fuel management arena. The passage of new energy legislation; the need for more US nuclear energy; growing state, national and international momentum for carbon emission and other air pollutant reductions; post September 11. Homeland Security threat reduction improvements; desires to improve global nuclear security; rapidly emerging needs for clean electricity supplies in developing countries; and the technological advancements in advanced fuel cycle technologies provide a substantial foundation for future enhancements and improvements in current used nuclear fuel management programs. Past progress, lessons learned, and new used fuel/waste management technological innovations coupled with current and future economic, security, and environmental issues can create new approaches that can help the Federal government meet its obligations while simultaneously addressing many of the difficult regional/state issues that have historically hindered progress. This paper will examine and integrate the synergy of these issues to explore options and discuss possible new opportunities in the vitally important area of spent fuel management and the entire back end of the nuclear fuel cycle. (authors)

Implications of the New Regional Trade Agreements for the World Trading System

Directory of Open Access Journals (Sweden)

Agnes Ghibuțiu

2017-04-01

Full Text Available The year 2013 witnessed an outstanding rise in the pace and scale of negotiations on regional trade agreements (RTAs. While RTAs are not a new phenomenon, current negotiations involve multiple parties and/or major trading countries that have a significant combined economic weight, i.e. mega-RTAs. This paper looks at the recent surge in trade regionalism and addresses some of the key issues related to the potential impact of mega-RTAs upon the world trading system and global trade patterns. It examines the peculiarities of the new mega-RTAs and the factors underlying their proliferation, and discusses the main concerns raised by their foreseeable impact on excluded countries and the wider trading system. The paper finds that, if successfully concluded, mega-RTAs are likely to have far-reaching implications for the world trading regime, affecting its transparency and coherence. Nevertheless, the adverse effects could be cushioned through a revival of trading nations’ interest in the multilateral Doha Round talks.

The New World Information Order.

Science.gov (United States)

Masmoudi, Mustapha

1979-01-01

Argues for a reordering of the present conception of world information transmission dominated by the developed nations and characterized by imbalances in the political, legal, and technico-financial spheres. (JMF)

A New Globalization Paradigm: World Unity or Alternatives for Development?

Directory of Open Access Journals (Sweden)

Oleg Shvydanenko

2005-02-01

Full Text Available This article deals with the conceptual foundations of the modern global economic system of development. It reflects the cyclical nature of changes to and the details of global integration processes. The creation of a global economy from a multi-paradigmatic angle is briefly outlined, taking into account the modern paradigms of globalization and the predominance of alternatives to the future development of a global economic space. The article investigates the development of a new type of world economy, a multi-system with a proven role for linkages and a more consolidated world economy. The article reveals the initial conditions for and main qualitative changes related to the integrated development of a complex network of interdependent national societies and macro-regional geo-economic structures. The article also reveals changes in the configuration of those factors that provide competitiveness for these societies and geo-economic formations.

New nuclear weapon states and their impact on Third World regional conflicts

International Nuclear Information System (INIS)

Mazrui, A.A.

1986-01-01

The paper examines the new nuclear weapon states and their impact on third world regional conflicts. Nuclear technology in South Africa, nuclear terrorism and the Arab/Israeli conflict, Islam and the nuclear age, Egypt and the Non-Proliferation Treaty, and the 'masculinity' of warfare, are all discussed. (UK)

Virtual worlds: taking health promotion to new levels.

Science.gov (United States)

Annang, Lucy; Muilenburg, Jessica L; Strasser, Sheryl M

2010-01-01

Health promotion strategies continue to evolve, with interventions using e-mail, text messaging, and Web sites becoming commonplace. The use of online virtual worlds is a less familiar venue for health promotion but offers numerous possibilities for wired citizens with health issues. The authors discuss three examples of virtual worlds--the River City Project, Whyville, and Second Life--and how health promotion strategies can be implemented in virtual worlds. They also address several challenges associated with implementing health interventions in virtual worlds, including questions of ethics, diffusion of health knowledge and logistics of intervening outside of the real world.

The new worlds observer: The astrophysics strategic mission concept study

Directory of Open Access Journals (Sweden)

Cash W.

2011-07-01

Full Text Available We present some results of the Astrophysics Strategic Mission Concept Study for the New Worlds Observer (NWO. We show that the use of starshades is the most effective and affordable path to mapping and understanding our neighboring planetary systems, to opening the search for life outside our solar system, while serving the needs of the greater astronomy community. A starshade-based mission can be implemented immediately with a near term program of technology demonstration.

Magnetic brane-worlds

International Nuclear Information System (INIS)

Barrow, John D; Hervik, Sigbjorn

2002-01-01

We investigate brane-worlds with a pure magnetic field and a perfect fluid. We extend earlier work to brane-worlds and find new properties of the Bianchi type I brane-world. We find new asymptotic behaviours on approach to singularity and classify the critical points of the dynamical phase space. It is known that the Einstein equations for the magnetic Bianchi type I models are in general oscillatory and are believed to be chaotic, but in the brane-world model this chaotic behaviour does not seem to be possible

Local or systemic treatment for New World cutaneous leishmaniasis? Re-evaluating the evidence for the risk of mucosal leishmaniasis

NARCIS (Netherlands)

Blum, Johannes; Lockwood, Diana N. J.; Visser, Leo; Harms, Gundel; Bailey, Mark S.; Caumes, Eric; Clerinx, Jan; van Thiel, Pieter P. A. M.; Morizot, Gloria; Hatz, Christoph; Buffet, Pierre

2012-01-01

This review addresses the question of whether the risk of developing mucosal leishmaniasis (ML) warrants systemic treatment in all patients with New World cutaneous leishmaniasis (CL) or whether local treatment might be an acceptable alternative. The risk of patients with New World CL developing ML

Invasion of Old World Phragmites australis in the New World: precipitation and temperature patterns combined with human influences redesign the invasive niche

DEFF Research Database (Denmark)

Guo, Wen-Yong; Lambertini, Carla; Li, Xiu-Zhen

2013-01-01

niches. We suggest that an increase in precipitation in the 20(th) century, global warming and human-made habitats have shaped the invasive niches of the two lineages in the New World. However, as the invasions are on-going and human and natural disturbances occur concomitantly, the future distribution....... australis (Haplotype M and Med) in both their native and introduced ranges using environmental niche models (ENMs) to assess (i) whether a niche shift accompanied the invasions in the New World; (ii) the role of biologically relevant climatic variables and human influence in the process of invasion...... for temperature fluctuations and increased precipitation. The introduced Med lineage has enlarged its original subtropical niche to the tropics-subtropics, invading regions with a high annual mean temperature (> c. 10 °C) and high precipitation in the driest period. Human influence is an important factor for both...

Feminists eminists at the World Social Forum: Challenges for a New Political Culture

Directory of Open Access Journals (Sweden)

Lilian Celiberti

2003-01-01

Full Text Available The article deals with the ways of incursion of the feminist plurality’s significant expressions in the World Social Forum. These incursions express the changes in the subjectivities and in strategies of struggle that feminist movements in particular and social movements in general begin to develop, in the frame of a globalised world and in the new millennium. It’s an unprecedented process, that is promoting the development of new paradigms for collective action, that combines local and global issues, the interconnection of multiple agendas and the recovery of a more profound dimension of economic, social, cultural and symbolic justice, broadening, in this process, the concept of politics, the political and the power. The article sets discussion around the ways in which social movements converging in the Forum – that drag old dynamics and at the same time recreate new paradigms – work in politics and open the possibility of re-inventing an emancipation map and a social conception, capable of competing with neo-liberal consensus and with the single thought, recuperating diversity and plurality of social individuals and actors.

Ecuador Paraiso Escondido Virus, a New Flavivirus Isolated from New World Sand Flies in Ecuador, Is the First Representative of a Novel Clade in the Genus Flavivirus.

Science.gov (United States)

Alkan, Cigdem; Zapata, Sonia; Bichaud, Laurence; Moureau, Grégory; Lemey, Philippe; Firth, Andrew E; Gritsun, Tamara S; Gould, Ernest A; de Lamballerie, Xavier; Depaquit, Jérôme; Charrel, Rémi N

2015-12-01

A new flavivirus, Ecuador Paraiso Escondido virus (EPEV), named after the village where it was discovered, was isolated from sand flies (Psathyromyia abonnenci, formerly Lutzomyia abonnenci) that are unique to the New World. This represents the first sand fly-borne flavivirus identified in the New World. EPEV exhibited a typical flavivirus genome organization. Nevertheless, the maximum pairwise amino acid sequence identity with currently recognized flaviviruses was 52.8%. Phylogenetic analysis of the complete coding sequence showed that EPEV represents a distinct clade which diverged from a lineage that was ancestral to the nonvectored flaviviruses Entebbe bat virus, Yokose virus, and Sokoluk virus and also the Aedes-associated mosquito-borne flaviviruses, which include yellow fever virus, Sepik virus, Saboya virus, and others. EPEV replicated in C6/36 mosquito cells, yielding high infectious titers, but failed to reproduce either in vertebrate cell lines (Vero, BHK, SW13, and XTC cells) or in suckling mouse brains. This surprising result, which appears to eliminate an association with vertebrate hosts in the life cycle of EPEV, is discussed in the context of the evolutionary origins of EPEV in the New World. The flaviviruses are rarely (if ever) vectored by sand fly species, at least in the Old World. We have identified the first representative of a sand fly-associated flavivirus, Ecuador Paraiso Escondido virus (EPEV), in the New World. EPEV constitutes a novel clade according to current knowledge of the flaviviruses. Phylogenetic analysis of the virus genome showed that EPEV roots the Aedes-associated mosquito-borne flaviviruses, including yellow fever virus. In light of this new discovery, the New World origin of EPEV is discussed together with that of the other flaviviruses. Copyright © 2015 Alkan et al.

World Literature - World Culture

DEFF Research Database (Denmark)

Offering their own twenty-first-century perspectives - across generations, nationalities and disciplines -, the contributors to this anthology explore the idea of world literature for what it may add of new connections and itineraries to the study of literature and culture today. Covering a vast...... historical material these essays, by a diverse group of scholars, examine the pioneers of world literature and the roles played by translation, migration and literary institutions in the circulation and reception of both national and cosmopolitan literatures....

The systematics and evolution of New World primates - A review.

Science.gov (United States)

Schneider, Horacio; Sampaio, Iracilda

2015-01-01

This paper provides an overview of the taxonomy of New World primates from proposals of the 1980's based on morphology to the great number of studies based on molecular data aiming for the elucidation of the phylogeny of New World monkeys. The innovations of the first molecular phylogeny presented by Schneider et al. (1993) positioned Callimico as a sister group of Callithrix and Cebuella; Callicebus as a member of the pitheciids; Brachyteles as sister to Lagothrix; and the night monkeys (Aotus), capuchins (Cebus) and squirrel monkeys (Saimiri) in the same clade with the small callitrichines. These results were subsequently confirmed by dozens of subsequent studies using data from DNA sequences. Some issues difficult to resolve with the phylogenetic analyses of DNA sequences, such as the diversification of the oldest lineages (pitheciids, atelids and cebids), and the confirmation of Aotus as a member of the Cebinae clade (together with Cebus/Saimiri), were clarified with new molecular approaches based on the presence or absence of Alu insertions as well as through the use of phylogenomics. At this time, all relationships at the intergeneric level had been deciphered, with the exception of the definition of the sister group of callitrichines (whether Aotus or Cebus/Saimiri are sister to callitrichines, or if Aotus, Saimiri and Cebus form a clade together). Future studies should prioritize the alpha taxonomy of most Neotropical primate groups, and the use of phylogenetic and geographic data, combined with reliable estimates of divergence times, to clarify the taxonomic status at species and genus level, as well as to help understand the evolutionary history of this remarkable and highly diversified group. Copyright © 2013 Elsevier Inc. All rights reserved.

Construct new world history system——the enlightenment of China and Japan and Korea S. editing historical textbook of east Asia jointly

Institute of Scientific and Technical Information of China (English)

Jiang JunKai

2012-01-01

To constructs the new world history system, should function as the system to understand to intension and epitaxy of the world history, and also define the standard of establishing the system of new world history, on the basis of the existing

Global black p-brane world: a new approach to stable mass hierarchy

International Nuclear Information System (INIS)

Moon, Sei-Hoon; Rey, Soo-Jong; Kim, Yoonbai

2001-01-01

We find a class of extremal black hole-like global p-brane in higher-dimensional gravity with a negative cosmological constant. The region inside the p-brane horizon possesses all essential features required for the Randall-Sundrum type brane world scenario. The set-up allows to interpret the horizon size as the compactification size in that the Planck scale M Pl is determined by the fundamental scale M * and the horizon size r H via the familiar relation M Pl 2 ∼M * 2+n r H n , and the gravity behaves as expected in a world with n-extra dimensions compactified with size r H . Most importantly, a stable mass hierarchy between M Pl and M * can be generated from topological charge of the p-brane and the horizon size r H therein. We also offer a new perspective on various issues associated to the brane world scenarios including the cosmological constant problem

Small World Properties Generated by a New Algorithm Under Same Degree of All Nodes

International Nuclear Information System (INIS)

Li Yong; Fang Jinqing; Liu Qiang; Liang Yong

2006-01-01

Based on the model of the same degree of all nodes we proposed before, a new algorithm, the so-called 'spread all over vertices' (SAV) algorithm, is proposed for generating small-world properties from a regular ring lattices. During randomly rewiring connections the SAV is used to keep the unchanged number of links. Comparing the SAV algorithm with the Watts-Strogatz model and the 'spread all over boundaries' algorithm, three methods can have the same topological properties of the small world networks. These results offer diverse formation of small world networks. It is helpful to the research of some applications for dynamics of mutual oscillator inside nodes and interacting automata associated with networks.

The World At Night: A New International Year of Astronomy 2009 Project

Directory of Open Access Journals (Sweden)

Simmons, M.

2008-02-01

Full Text Available The World At Night (TWAN is a new programme founded in 2007 with the goal of creating a collection of stunning photographs of the world’s most beautiful and historic sites against the night-time backdrop of stars, planets, and celestial events. The eternally peaceful sky looks the same above all the symbols of different nations and regions, a testament to the truly unified nature of Earth as a planet rather than an amalgam of human-designated territories. Those involved in global programmes learn to see humanity as a family living together on a single planet amidst the vast ocean of our Universe. This global perspective motivates us to work for a better, more peaceful planet for all the world’s inhabitants. TWAN is an innovative approach to expanding this global perspective. TWAN’s primary goal is to present the public with a new and enlightening view of the wonders of our planet by revealing the unified nature of Earth’s people as one family and our world as a living planet that we must all care for together.

New Vaccines for the World's Poorest People.

Science.gov (United States)

Hotez, Peter J; Bottazzi, Maria Elena; Strych, Ulrich

2016-01-01

The 2000 Millennium Development Goals helped stimulate the development of life-saving childhood vaccines for pneumococcal and rotavirus infections while greatly expanding coverage of existing vaccines. However, there remains an urgent need to develop new vaccines for HIV/AIDS, malaria, and tuberculosis, as well as for respiratory syncytial virus and those chronic and debilitating (mostly parasitic) infections known as neglected tropical diseases (NTDs). The NTDs represent the most common diseases of people living in extreme poverty and are the subject of this review. The development of NTD vaccines, including those for hookworm infection, schistosomiasis, leishmaniasis, and Chagas disease, is being led by nonprofit product development partnerships (PDPs) working in consortia of academic and industrial partners, including vaccine manufacturers in developing countries. NTD vaccines face unique challenges with respect to their product development and manufacture, as well as their preclinical and clinical testing. We emphasize global efforts to accelerate the development of NTD vaccines and some of the hurdles to ensuring their availability to the world's poorest people.

Looking for ‘Home’? New Zealand Soldiers Visiting London during the First World War

OpenAIRE

Maguire, Anna

2016-01-01

For colonial troops from the British Empire, the military mobilizations of the First World War created the opportunity to visit the imperial metropolis – London – leaving the war behind. This article explores the experience and encounters of New Zealand's soldiers in London during the First World War and the ambiguity of their identity and belonging in a city that could be positioned as ‘home’. Using diaries, letters, newspapers and oral testimonies, the article builds on the work of Felicity...

Children's Worlds: An Exploration of Latino Students' Play in Rural New Mexico

Science.gov (United States)

Ulibarri, Reyna M.

2016-01-01

I present an ethnographic study of thirteen nine-year-old, U.S.-born Latino children in rural New Mexico. I employ in-depth individual and group interviews, participant observation, and sand play (a method borrowed from clinical psychology in which children "make a world" in a box of sand) to explore how play interactions represent,…

Energetic diplomacy and its role on creation of a new multipolar world

Directory of Open Access Journals (Sweden)

Igor Gelev

2016-01-01

Many of us would ask does this mean the reincarnation of the so called almost forgotten Cold War only now coming in such a shape that seems to be far more terrifying in character with a great deal of chance to impose the brink of a new world war and another humanitarian wash-out to humanity.

The injury profile of Karate World Championships: new rules, less injuries.

Science.gov (United States)

Arriaza, Rafael; Leyes, Manuel; Zaeimkohan, Hamid; Arriaza, Alvaro

2009-12-01

The aim of this paper is to document the injury rate in high-level modern competitive karate after a change of competition rules was implemented in the year 2000, and to compare it with the injury rate found before the rules were changed. A prospective recording of the injuries resulting from 2,762 matches in three consecutive World Karate Championships (representing 7,425 min of active fighting) was performed, and compared with the results from 2,837 matches from the three last World Karate Championships (representing 7,631 min of active fighting) held before the change of competition rules. In total, 497 injuries were recorded, with an incidence of 0.180 injuries per match or 6.7 per 100 min of active fighting. There were 1,901 male category fights (in which 383 injuries were recorded), and 861 female category fights (in which 114 injuries were recorded). The global injury incidence was almost double with the old rules compared to the one with the new rules [OR 1.99, 95% CI (1.76-2.26); p injuries was not different before and after the change of rules. The implementation of the new competition rules in competitive karate has been associated with a significant reduction in injury rate, making competition safer for athletes.

In the Face of the Strategic Choice: New Imperatives of World Policy

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Mark A. Neymark

2017-01-01

Full Text Available The article analyzes global changes in the international arena, which in a concentrated form reflect the dynamics of the most complicated geopolitical processes, the dialectics of the interconnection of the old and the new in the world politics. We study its problem nodes and key issues. The world political process is considered as an expression of a flexible mobility, variability, dynamic interaction of a multitude of objective and subjective factors that determine the content, nature and vectors of the evolution of the world community. The author focuses on the systemic set of interdependent subprocesses: global, regional, local-country, inertial, crisis, etc. Dialectical interrelations of national and global in world politics are traced. Great attention is paid to the role of social networks in the global space. The peculiarities of the globalization of information processes, their influence on the alignment of forces in the world arena, geopolitical capabilities and the potential of the information sphere in the competitive rivalry of states are revealed. The strategic lines of Russia’s foreign policy are analyzed taking into account the latest trends that determine its geopolitical status and place in the world community. In the actual problematic refraction, the features of Russophobia in world politics, its phantoms and realities are being comprehended. The most important issue of world politics — achieving geopolitical goals by increasing the desirable or reducing the undesirable is being conceptualized. Geopolitically, it is extremely important that it is the cultural and humanitarian imperative that lies at the basis of «soft («flexible or intelligent» power», which comes to the forefront of world politics. «Soft power» is considered as a comprehensive tool for solving foreign policy problems with the support of the opportunities of civil society, information and communication, humanitarian and other methods and

Darwin's bee-trap: The kinetics of Catasetum, a new world orchid.

Science.gov (United States)

Nicholson, Charles C; Bales, James W; Palmer-Fortune, Joyce E; Nicholson, Robert G

2008-01-01

The orchid genera Catasetum employs a hair-trigger activated, pollen release mechanism, which forcibly attaches pollen sacs onto foraging insects in the New World tropics. This remarkable adaptation was studied extensively by Charles Darwin and he termed this rapid response "sensitiveness." Using high speed video cameras with a frame speed of 1000 fps, this rapid release was filmed and from the subsequent footage, velocity, speed, acceleration, force and kinetic energy were computed.

A "New Silk Road" Between China and the Arab World

DEFF Research Database (Denmark)

Zank, Wolfgang

2014-01-01

The chapter reconstructs the development of new links between China and the Arab World. The links have been created from "above" and from "below", by private initiatives. This process has been facilitated by a turn to more open economic systems on both sides. The relations are closest between Chi...... and the oil-exporting Gulf States. The main motive on the Chinese side has been the support of China's own economic development. The developments imply no threat against Western interests, on the contrary, Western countries have profited from it....

The New Leader of the Free World

Science.gov (United States)

Williamson, Kevin D.

2012-01-01

On January 20, 2009, Dr. Manmohan Singh, the prime minister of India, became the leader of the free world. The free world's attention was focused elsewhere: Senator Barack Obama, who on that day became President Barack Obama, quietly abdicated the role now taken up by Dr. Singh, having run an election campaign premised upon the ever-present but…

Amphibious shelter-builder Oniscidea species from the New World with description of a new subfamily, a new genus and a new species from Brazilian cave (Isopoda, Synocheta, Styloniscidae).

Science.gov (United States)

Souza, Leila A; Ferreira, Rodrigo L; Senna, André R

2015-01-01

The new subfamily Iuiuniscinae, Styloniscidae, is erected for the new genus Iuiuniscus and the new species I. iuiuensis, which is described from cave of the State of Bahia, Northeastern Brazil. A special ecological character is shown here for the first time for a New World Oniscidea: the construction of mud shelters. An introduction addressing the systematics of Synocheta with emphasis on Styloniscidae Vandel, 1952 is provided, as well as general comments about the dependence of water in some Oniscidea and ecological traits of amphibious Synocheta. The problems referring to nomenclature, taxonomy and the interrelationships in Styloniscidae are discussed.

Amphibious shelter-builder Oniscidea species from the New World with description of a new subfamily, a new genus and a new species from Brazilian cave (Isopoda, Synocheta, Styloniscidae.

Directory of Open Access Journals (Sweden)

Leila A Souza

Full Text Available The new subfamily Iuiuniscinae, Styloniscidae, is erected for the new genus Iuiuniscus and the new species I. iuiuensis, which is described from cave of the State of Bahia, Northeastern Brazil. A special ecological character is shown here for the first time for a New World Oniscidea: the construction of mud shelters. An introduction addressing the systematics of Synocheta with emphasis on Styloniscidae Vandel, 1952 is provided, as well as general comments about the dependence of water in some Oniscidea and ecological traits of amphibious Synocheta. The problems referring to nomenclature, taxonomy and the interrelationships in Styloniscidae are discussed.

It's a Whole New World.

Science.gov (United States)

Novelli, Joan

1994-01-01

The article presents technology projects that provide real-life reasons for students to learn geography. A variety of online networks take students on online field trips, linking them with scientists, zoologists, archaeologists, and explorers. Other interactive software is available to simulate trips to various locations around the world. (SM)

Carnival in the Old World and the New

Directory of Open Access Journals (Sweden)

Burke, Peter

1996-06-01

Full Text Available There are three distinct, traditional views of Carnival. The author, following Caro Baroja, argues that all three are equally valid. «The festival —he writes— was Protean, appealing to different people for different reasons». Besides, it has changed through time and space. When transferred to the New World by Mediterranean immigrants, it was transformed as the result of transculturation; for instance, by incorporating African components that were absent in the Old World. Nonetheless, the development of the festival in the Americas over the past two centuries has followed the same stages of the European Carnival between the l6th and the 19th centuries.La bibliografía sobre el carnaval permite distinguir tres interpretaciones diferentes de esta fiesta, ya expuestas en el siglo XVI. El autor, sin embargo, siguiendo a Caro Baroja, se niega a tener que elegir a cualquiera de ellas como la más adecuada. «El festival —escribe— era proteico; atraía a diferentes personas por razones diferentes». Además, ha cambiado en el tiempo y en el espacio. Cuando fue llevado a América por inmigrantes mediterráneos, se transformó como resultado de la transculturación; incorporando, por ejemplo, componentes africanos que no tenía el carnaval europeo. No obstante, su desarrollo en América en los dos últimos siglos ha repetido el que tuvo en Europa entre los siglos XVI y XIX.

Globalization and new world order are we ready for "Scientists without Borders"?

CERN Document Server

Kouchner, B

2005-01-01

Since the end of the cold war and the fall of the Berlin wall, large scientific projects, such as the LHC and ITER, are now based on international collaborations involving most world powers. These collaborations cover not only the design, but also run the construction and operation phases. Scientists, like other cultural and economical actors, have to adapt and organize their work in this new world environment. They also need to learn how to convince public opinion, offering information and transparency. There is no good model yet on how to do that in the most efficient way and a great deal might be learned by looking at experiences outside the scientific field. Relying on my experience as founder of "Doctors Without Borders" and "Doctors of the World", as well as holder of several ministerial positions in different French governments and as former Head of the UN Interim Administration Mission in Kosovo, I share with you my view on globalization and on how to initiate and carry out large international, nonpro...

The World Oil Market: The Search for Balance in the New “Oil” Reality

Directory of Open Access Journals (Sweden)

Tatjiana A. Malova

2016-01-01

Full Text Available The article provides an analysis of change of the world oil market in the face of new "oil" reality. Factors of formation of new "oil" reality in the global world defined. Scientific background and current state of research of the problem are described. It is shownthat in the Russian and foreign literature the considerable attention is paid to the analysis of dynamics of the quantitative variables characterizing fluctuations and shocks in the oil market. At the same time the search for balance in the new "oil" reality are not considerably investigated yet. The proposed approach allows toreveal the substance of the transformation of the world oil market, to assess the changes in the oil market with the development of rhenium in terms of efficiency and functioning of the mechanism, the prospects of price volatility in the oil market. The main directions of transformation of the oil market are follows. Development of a subject basis of the oil market due to changes of a role of the main market players whose structure includes the USA, Saudi Arabia, Russia now. The impact of regulatory factors complex in the oil market towards equilibrium, which include activity of OPEC, supply of shale oil, future market,activity of the uniform regulator and national regulators. Transformation of the oil market in the direction of perfection of the competitive relations, achievement of optimum market balance as a result of coordination and interaction of interests of participants of the global oil market.

Cooperative Security: A New Paradigm For A World Without Nuclear Weapons?

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Marc Finaud

2013-11-01

Full Text Available If there is a loose consensus on aiming at a world free of nuclear weapons in the future, there are clear oppositions as to the timeframe as well as the means for achieving this goal. The approach to nuclear disarmament followed to date has only yielded limited success because it has been conceived in isolation from global and regional security environments and threat perceptions. A new paradigm should thus be sought in order to reconcile nuclear powers’ security doctrines with global aspirations for a safer world, and ensure that nuclear powers derive their security less from others’ insecurity but from mutually beneficial cooperative security. This should not become a pretext for preserving nuclear weapons for ever. It will on the contrary require parallel tracks addressing the initial motivations for acquiring nuclear weapons and other weapons of mass destruction (WMD, in particular in the context of regional conflicts, as well as dealing with the current issues necessarily related to nuclear disarmament (missile defence, weaponization of space, conventional imbalances and future weapon systems. Ultimately, in a globalised nuclear-weapon free world, state security will not require nuclear weapons because it will be inserted into a broader network encompass­ing all aspects of security addressed in cooperative and multilateral approaches.

The Food Crisis and Food Security: Towards a New World Food Order?

Directory of Open Access Journals (Sweden)

Christophe Golay

2010-03-01

Full Text Available The worst food crisis since 1974 broke out in 2007-08. Higher world market prices of food commodities (especially wheat, rice, soya and maize sparked an unprecedented increase in the number of hungry people. Despite moderately lower prices since the summer of 2008, the number of the hungry continued to rise in 2009. This food crisis has placed the fight against hunger on the international agenda. Since March 2008 governments UN agencies and many social movements have adopted positions on the causes of the crisis and the means to address it. Unfortunately, while these parties are trying to coordinate their activities and suggest new approaches, the old recipes for producing more food are often brought up. Contradictory proposals are made and the thought given to the causes underlying hunger and the food crisis (social, economic and political discrimination and exclusion has gone largely unheeded. The first Millennium Development Goal, which calls for cutting the percentage of hungry people by half by 2015, is clearly out of reach. But the food crisis might lead to a new world food order based on the three pillars of food assistance, food security and the right to food.

The evaluation of Cu, Zn, Mn, and Se concentrations in the hair of South American camelids

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Milada Holasová

2017-01-01

Full Text Available The aim of this study was to monitor the content of trace elements in the hair of South American camelids and to evaluate the effect of coat colour, species, age, and sex on their concentration in the hair. The samples were collected from 77 animals – 23 llamas (Llama guanicoe f. gllama and 54 alpacas (Llama guanicoe f. pacos during a spring health check. The concentrations of copper (Cu, zinc (Zn, and manganese (Mn were determined by Flame Atomic Absorption Spectrometry and selenium (Se by Hydride Generation Atomic Absorption Spectrometry. We found the following concentrations (mean ± standard deviation; mg/kg dry matter in the llama hair: Cu 9.70 ± 4.69; Zn 145.20 ± 21.07; Mn 12.49 ± 10.14; Se 0.25 ± 0.14. In alpaca hair we found the following concentrations: Cu 10.22 ± 2.90; Zn 129.81 ± 19.01; Mn 12.67 ± 13.85; Se 0.48 ± 0.24. We found a significant difference between llamas and alpacas in Zn and Se concentrations in the hair. From all the evaluated factors we found that coat colour had the highest effect on Mn and Se concentration. Dark haired animals had significantly higher concentrations of these trace elements than other coloured groups. The evaluation of the concentration of trace elements in the hair of llamas has a potential to be used for the evaluation of long-term status of trace elements in the body; however, it is necessary to continue with experimental work in this area. Our findings can serve as a pilot study for further works in this field.

[Dry matter intake of South American camelids and its effects on the composition of feed rations].

Science.gov (United States)

Stölzl, Anna Maria; Lambertz, Christian; Moors, Eva; Stiehl, Jennifer; Gauly, Matthias

2014-01-01

The number of South American camelids (SAC) is increasing in Germany since decades. Due to a lack of scientifically based publications the knowledge about feeding SACs is still poor. Therefore, the aim of this study was to estimate the dry matter intake (DMI) of SACs as a basis for calculations of feed rations. Previous studies proposed a DMI of up to 3% of the body weight (BW) (Vaughan und Gauly, 2011). In the present study, eight llamas (Llama glama) were allocated to two groups of four animals each. The two groups were fed with hay of different qualities over a total period often weeks, which was divided into two runs of five weeks each. During the first run, group 1 was fed with hay 1 (15.1% crude protein; 8.5% crude ash; 3.1% crude fat; 52.6% NDF per kg DM) and group 2 with hay 2 (6.6% crude protein; 6.2% crude ash; 2.1% crude fat; 64.3% NDF per kg DM). After five weeks the groups were changed and group 1 received hay 2 and group 2 received hay 1. BW was measured at the start and end of each run (week zero, five and ten). The hay quality affected the DMI, but the animals did not compensate a lower feed quality with an increased DMI. The total DMI was 1.26% and 0.89% of the BW for hay 1 and hay 2, respectively, which was lower than expected in both groups. In conclusion, calculations of feed rations for SACs should be adjusted to the present findings of a lower DMI capability.

Population policy at a crossroads. Will world conference signal new directions for U.S.?

Science.gov (United States)

Mccarty, L; Sherman, D

1994-06-01

In September 1994 in Cairo, at the third population conference hosted by the United Nations, world leaders will be asked to approve a plan that could stabilize the world population at about 8 billion people by the middle of the next century. Participants will consider interrelated issues: population growth, access to family planning, women's empowerment, sustainable development, poverty, consumption, and the environment. This campaign for a more equitable world is likely to continue after Cairo, with the UN-sponsored social summit in Copenhagen and a women's conference in Beijing slated for next year. The Cairo International Conference on Population and Development will require a new approach to sustainability by balancing environmental protection, economic development, and present and future human needs. The United States has only 5% of the world's population, but it uses 25% of the world's commercial energy, produces more garbage and waste than any other country, and generates 21% of all carbon dioxide emissions, which contribute to global warming. Demands for energy, water and food already cannot be met as natural resources are being exhausted at an alarming rate. The fight over water rights to the Colorado River exemplifies the shrinking natural resource base. In contrast to the Reagan-Bush administration, the Clinton administration restored funding to international family planning agencies and endorsed sustainable development. The US birth rate is back at a 2-decade high, while 60% of pregnancies are unintended. US adolescent pregnancy is the highest among industrialized countries, leading to a cycle of poverty and soaring public costs. Government funding for new contraceptive research has been stagnant because of the pressure of right-wing groups, although finally RU-486 became available for clinical trials. The Cairo conference is likely to recognize the US as the leader in global political issues, however, domestic population and consumption issues have

From ‘machine-world’ to ‘God-world’ - world pictures and world views 1

Directory of Open Access Journals (Sweden)

J. J. Venter

1992-03-01

Full Text Available This article mainly consists of an analysis of the successive historical expansions of the mechanistic and the organistic world pictures into world views. In conclusion the presently popular form of the organistic world view, New Age occultism, is compared with the 'traditional' African world view. In this way the author attempts to realise three different aims: firstly to show how world pictures, developed within specific disciplines, are transformed into world views by expansionary application in other disciplines and /or cultural areas; secondly that occultism is regaining intellectual respectability by presenting itself as part of the ‘new’ organistic, scientific view of the world; and thirdly that there are strong similarities between the new Western occultism and the traditional African world view (which opens up possibilities of synthesis between these two.

A new mealybug in the genus Pseudococcus Westwood (Hemiptera: Coccomorpha: Pseudococcidae) from North America, with a key to species of Pseudococcus from the New World.

Science.gov (United States)

Ellenrieder, Natalia Von; Watson, Gillian

2016-04-19

A mealybug species that feeds on Agave spp., Pseudococcus variabilis sp. n. (Hemiptera: Coccomorpha: Pseudococcidae), is described from North America. Its entry into the United States was likely via the horticultural trade on its host plants in the genus Agave (Liliales: Agavaceae). Descriptions and illustrations of the adult female and male, diagnosis from congeners in the New World, and a molecular characterization based on COI are provided, as well as a key to adult females of all Pseudococcus species recorded from the New World.

New NIH-funded Ultrasound Technology is Changing Lives around the World | NIH MedlinePlus the Magazine

Science.gov (United States)

... version of this page please turn Javascript on. New NIH-funded Ultrasound Technology is Changing Lives around the World Past Issues / ... stage for further expansion of medical ultrasound into new areas." To ... ultrasound technology: www.youtube.com/watch?v=6n8xZECzEck& feature= ...

Livestock systems and rangeland degradation in the new World Atlas of Desertification

Science.gov (United States)

Zucca, Claudio; Reynolds, James F.; Cherlet, Michael

2015-04-01

Livestock systems and rangeland degradation in the new World Atlas of Desertification Land degradation and desertification (LDD), which are widespread in global rangelands, are complex processes. They are caused by multiple (but limited) number of biophysical and socioeconomic drivers that lead to an unbalance in the capacity of the land to sustainably produce ecosystem services and economic value. Converging evidence indicates that the key biophysical and socioeconomic drivers include agricultural or pastoral land use and management practices, population growth, societal demands (e.g., urbanization), and climate change (e.g., increasing aridity and drought). The new World Atlas of Desertification (WAD) describes these global issues, documents their spatial change, and highlights the importance of these drivers in relation to land degradation processes. The impacts of LDD on the atmosphere, on water and on biodiversity are also covered. The WAD spatially illustrates relevant types of livestock and rangeland management systems, related (over-under) use of resources, various management activities, and some of the common features and transitions that contribute to LDD. For example, livestock grazing in marginal areas is increasing due to competition with agricultural encroachment and, hence, vulnerable lands are under threat. The integration of stratified global data layers facilitates identifying areas where stress on the land system can be linked to underlying causal issues. One of the objectives of the new WAD is to provide synthesis and tools for scientists and stakeholders to design sustainable solutions for efficient land use in global rangelands.

When Virtual Worlds Expand

Science.gov (United States)

Bainbridge, William Sims

The future of a virtual world depends on whether it can grow in subjective size, cultural content, and numbers of human participants. In one form of growth, exemplified by Second Life, the scope of a world increases gradually as new sponsors pay for new territory and inhabitants create content. A very different form of growth is sudden expansion, as when World of Warcraft (WoW) added entire new continents in its Burning Crusade and Lich King expansions (Lummis and Kern 2006, 2008; Corneliussen and Rettberg 2008; Sims et al. 2008). Well-established gamelike worlds have often undergone many expansions. Both the pioneer science fiction game Anarchy Online, which was launched in 2001, and Star Wars Galaxies dating from 2003, have had three, and EVE Online also from 2003 has had nine, although smaller ones. This chapter reports research on WoW's 2008 Lich King expansion, using both quantitative and qualitative methods, in order to develop theoretical ideas of the implications of expansion for virtual worlds.

Virtual worlds: a new frontier for nurse education?

Science.gov (United States)

Green, Janet; Wyllie, Aileen; Jackson, Debra

2014-01-01

Virtual worlds have the potential to offer nursing students social networking and, learning, opportunities through the use of collaborative and immersive learning. If nursing educators, are to stay, abreast of contemporary learning opportunities an exploration of the potential benefits of, virtual, worlds and their possibilities is needed. Literature was sourced that explored virtual worlds, and their, use in education, but nursing education specifically. It is clear that immersive learning has, positive, benefits for nursing, however the best way to approach virtual reality in nursing education, has yet to, be ascertained.

New Lens Scenarios. A Shift in Perspective for a World in Transition

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-02-15

With the world's population headed toward 9 billion at mid-century and millions of people climbing out of poverty, global energy demand could increase by as much as 80% by 2050. That's according to Shell's latest scenarios, which look at trends in the economy, politics and energy in considering developments over the next half a century. The first scenario (Mountains) sees a strong role for government and the introduction of firm and far-reaching policy measures. These help to develop more compact cities and transform the global transport network. New policies unlock plentiful natural gas resources - making it the largest global energy source by the 2030s - and accelerate carbon capture and storage technology, supporting a cleaner energy system. The second scenario (Oceans) describes a more prosperous and volatile world. Energy demand surges, due to strong economic growth. Power is more widely distributed and governments take longer to agree major decisions. Market forces rather than policies shape the energy system: oil and coal remain part of the energy mix but renewable energy also grows. By the 2070s solar becomes the world's largest energy source.

New Lens Scenarios. A Shift in Perspective for a World in Transition

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-02-15

With the world's population headed toward 9 billion at mid-century and millions of people climbing out of poverty, global energy demand could increase by as much as 80% by 2050. That's according to Shell's latest scenarios, which look at trends in the economy, politics and energy in considering developments over the next half a century. The first scenario (Mountains) sees a strong role for government and the introduction of firm and far-reaching policy measures. These help to develop more compact cities and transform the global transport network. New policies unlock plentiful natural gas resources - making it the largest global energy source by the 2030s - and accelerate carbon capture and storage technology, supporting a cleaner energy system. The second scenario (Oceans) describes a more prosperous and volatile world. Energy demand surges, due to strong economic growth. Power is more widely distributed and governments take longer to agree major decisions. Market forces rather than policies shape the energy system: oil and coal remain part of the energy mix but renewable energy also grows. By the 2070s solar becomes the world's largest energy source.

After the world court opinion: Towards a world without nuclear weapons

International Nuclear Information System (INIS)

Roche, D.

1998-01-01

With the World Court advisory opinion on the treat or use of nuclear weapons, a new moment has arrived in the 51-year history of atomic bomb. The highest legal body in the world has said that governments must not only pursue but conclude negotiations leading to total nuclear disarmament. Both a sharp focus and a comprehensive action are required in developing public support and political action towards a safer, more peaceful world. Three-pronged interrelated course of action is proposed: a Nuclear Weapon Convention; reduction in conventional arms and control of arms trade; and new spending priorities or sustainable development

New world balance and emerging countries - democracy, energy, technology

International Nuclear Information System (INIS)

Coulom, Steve

2011-01-01

The serious economic crisis which rages since 2008 has been the result of a troubled era which started years before and contributed to aggravate the phenomenon. Energy crisis, biodiversity loss, global warming and its effects, markets deregulation have added up to economic recession. We are today the witnesses of a new deal of the cards illustrated by the social revolts of several Arab countries around the Mediterranean Sea. In this changing world, the declining occident cannot impose its economical or political leadership and the main emerging countries (Brazil, Russia, India, China and South Africa: BRICS) play a more and more important role. With 30% of population increase expected in 2050, the emerging countries represent the driver of the world growth and have become the keys of development questions. In front of this irreversible movement, urgent and worldwide changes have to be done. First of all, huge technological efforts and changes of the existing international institutions (IMF, UNO, WTO) and of their governance are necessary to build up a sustainable economy and energy policy with emerging countries. Such a transformation will be painful for the Occident as it will change its vision of growth based on political domination and search of financial wealth, energy and resources. It is this effort that the author aims to present in this book in a practical and visionary way, where technological progress occupies an important place

Virtual-World Naturalism

Directory of Open Access Journals (Sweden)

Daniel Reynolds

2010-07-01

Full Text Available Sometimes a player will stray from the path described by a game, moving into new spaces, developing new possible modes of interaction, and often discovering the rougher edges of the game world, where physics models break down, textures become incongruous, and the pieces don’t quite fit together. Gameplay that seeks out these spaces and these phenomena, that searches for such clues to the underlying construction of the virtual environment, is a kind of virtual-world naturalism, at once a return to an investigative urge that has been subsumed to the exhaustive mapping and description of the real world and a form of resistance to the very idea of pre-defined paths of action, of externally imposed limits, in virtual worlds as well as in our own.

Can old-world and new-world monkeys judge spatial above/below relations to be the same or different? Some of them, but not all of them.

Science.gov (United States)

Thompson, Roger K R; Flemming, Timothy M; Hagmann, Carl Erick

2016-02-01

Chimpanzees (Pan troglodytes) with the aid of token training can achieve analogical reasoning, or the ability to understand relations-between-relations (e.g., Premack, 1976; Thompson, Oden, & Boysen, 1997). However, extraordinarily few numbers of old- and new-world monkeys have demonstrated this ability in variants of relational matching to sample tasks. Moreover, the rarity of replications leaves open the question of whether the results are normative for other captive colonies of the same species. In experiment one we attempted to replicate whether old world rhesus monkeys (Macaca mulatta) might demonstrate the same level of proficiency on a spatial above/below relational matching task as reported for old world baboons (Papio papio). None of the rhesus monkeys attained above chance performances over 10,000 training trials. In experiment two we attempted to replicate results demonstrating that new-world capuchin monkeys (Cebus apella) match above/below relations. The capuchin monkeys performed above chance only in the absence of 'Clever Hans' controls for cuing of the correct choice by the experimenters. These failures to replicate previously reported results demonstrate that some, but definitely not all monkeys can judge the equivalence of abstract 'relations between relations' and warrant further investigations into the behavioral and cognitive characteristics that underlie these similarities and differences within population and between individuals of different primate species. Copyright © 2015 Elsevier B.V. All rights reserved.

Appalachian spring: variations on ancient gastro-entero-pancreatic themes in New World mammals.

Science.gov (United States)

Seino, S; Blackstone, C D; Chan, S J; Whittaker, J; Bell, G I; Steiner, D F

1988-07-01

Studies of guinea pig genomic and/or cDNA clones encoding the gastro-entero-pancreatic (GEP) hormones--insulin, glucagon and pancreatic polypeptide--as well as portions of the insulin receptor, are described. Multiple clustered substitutions (localized rapid mutation acceptance) altering the biological properties of both insulin and glucagon have been revealed, but this does not appear to be the case with either pancreatic polypeptide or those regions of guinea pig insulin receptor cDNAs that have been examined thus far. These findings suggest that novel selective pressures operative in the New World environment, in which these animals evolved in isolation from Old World mammalian species, have led to altered solutions to problems related to the regulation of growth and carbohydrate metabolism.

Diplomatic History of the Great Patriotic War and the New World Order

Directory of Open Access Journals (Sweden)

Alexander Y. Borisov

2015-01-01

Full Text Available From ancient times, war was called "the creator of all things". And winners created the postwar world order. The article reveals the backstage, the diplomatic history of the Great Patriotic War, which make the picture of the main events of the war, that culminated in victory May 1945 in the capital of the defeated Third Reich, complete. The decisive role of the Soviet Union and its armed forces in the defeat of Nazi Germany and its allies was the strong foundation on which to build the strategy and tactics of Soviet diplomacy during the war. It was implemented in the course of negotiations with the Western Allies - the United States and Britain, led by President Roosevelt and Prime Minister Churchill. World history teaches, large and small wars have been fought on Earth for centuries for specific political interests. In this context, the Second World War has been a shining example not only to curb the aggressor states, the liberation of peoples from the Nazi tyranny, but also an attempt by the victor to organize a new, better postwar world order to guarantee a durable and lasting peace based on the cooperation of the allied states. But the allies in the war did not become allies in the organization of the postwar world. Their collaboration briefly survived the end of hostilities and was overshadowed start turning to the Cold War. It was largely due to the US desire to realize their material advantages to the detriment of the Soviet Union after the war and build a system that would be a one-sided expression of the interests of Washington. Americans, especially after the death of President Roosevelt, and during his successor Truman understood international cooperation as an assertion of its global leadership while ignoring the interests of the Soviet Union, which bore the brunt of the war.

Revision of the new world species of Hylurgops LeConte, 1876 with the description of a new genus in the Hylastini (Coleoptera: Scolytinae) and comments on some Palearctic species

Science.gov (United States)

Javier E. Mercado-Velez; Jose F. Negron

2014-01-01

The New World species of the genus Hylurgops LeConte are revised and Hylurgops subcostulatus Mannerheim is transferred to the new genus Pachysquamus. A revised key to the tribe Hylastini which can be used for the world fauna is presented to include Pachysquamus. Our studies suggest that the Nearctic species H. knausi Swaine is a valid taxon, distinguishable from the...

Brave New Worlds. Shakespearean Tempests in Italian Prisons

Directory of Open Access Journals (Sweden)

Mariacristina Cavecchi

2017-11-01

Full Text Available Shakespeare is a pivotal and much staged playwright by theatre companies of prisoners in Italy, even though the practice of theatre in prison in Italy has a much shorter tradition than in the Anglo-Saxon world. Among the many Shakespearean plays, "The Tempest" is a favourite, being obviously able to shine a new light on the themes of revenge, freedom and forgiveness that are central issues in a prison context. Undeniably, in Italy, productions of "The Tempest" in prison have deeply instilled new life into the staging of the Elizabethan playwright. The list includes different kinds of experiences ranging from drama therapy, where the process towards rehabilitation and reintegration is more important than the finished aesthetic product, to productions by theatre directors who are primarily concerned with the artistic medium of the theatre and its aesthetic qualities. A survey of Shakespeare theatrical practice in Italian prisons can help investigate and understand not only the aesthetic but also the political, social and economic consequences of the function of prison nowadays, and provides the first step towards an analysis of Shakespeare practice in Italian prisons in a broader context. By comparison with other European countries, we may also discover that some Italian experiences, such as Fabio Cavalli's work in Rome at the Rebibbia prison, or Armando Punzo's with the "Fortress Company" in Volterra are unique and they deserve more attention.

New Worlds / New Horizons Science with an X-ray Astrophysics Probe

Science.gov (United States)

Smith, Randall K.; Bookbinder, Jay A.; Hornschemeier, Ann E.; Bandler, Simon; Brandt, W. N.; Hughes, John P.; McCammon, Dan; Matsumoto, Hironori; Mushotzky, Richard; Osten, Rachel A.;

Oil-producing flowers within the Iridoideae (Iridaceae): evolutionary trends in the flowers of the New World genera.

Science.gov (United States)

Chauveau, Olivier; Eggers, Lilian; Souza-Chies, Tatiana T; Nadot, Sophie

2012-08-01

Oil-producing flowers related to oil-bee pollination are a major innovation in Neotropical and Mexican Iridaceae. In this study, phylogenetic relationships were investigated among a wide array of New World genera of the tribes Sisyrinchieae, Trimezieae and Tigridieae (Iridaceae: Iridoideae) and the evolution of floral glandular structures, which are predominantly trichomal elaiophores, was examined in relation to the diversification of New World Iridaceae. Phylogenetic analyses based on seven molecular markers obtained from 97 species were conducted to produce the first extensive phylogeny of the New World tribes of subfamily Iridoideae. The resulting phylogenetic hypothesis was used to trace the evolutionary history of glandular structures present in the flowers of numerous species in each tribe. Hypotheses of differential diversification rates among lineages were also investigated using both topological and Binary-State Speciation and Extinction methods. Floral glandular structures and especially trichomal elaiophores evolved multiple times independently in the American tribes of Iridoideae. The distribution pattern of species displaying glandular trichomes across the phylogeny reveals lability in the pollination system and suggests that these structures may have played a significant role in the diversification of the Iridoideae on the American continent.

Technical Progress of the New Worlds Observer Mission

Science.gov (United States)

Lo, Amy; Noecker, C.; Cash, W.; NWO Study Team

2009-01-01

We report on the technical progress of the New Worlds Observer (NWO) mission concept. NWO is a two spacecraft mission that is capable of detecting and characterizing extra-solar, terrestrial planets and planetary systems. NWO consists of an external starshade and an UV-optical space telescope, flying in tandem. The starshade is a petal-shaped, opaque screen that creates an extremely dark shadow large enough to shade the telescope aperture from the target star. The NWO team has been addressing the top technology challenges of the concept, and report here our progress. We will present the current mission configuration best suited to address Terrestrial Planet Finding requirements, and highlight the technological breakthroughs that we have achieved this year. In particular, we will report on progress made in precision deployables for the large starshade, and the trajectory & alignment control system for NWO. We will also briefly highlight advances in understanding the starshade optical performance.

Successful use of camelid (alpaca) antivenom to treat a potentially lethal tiger snake (Notechis scutatus) envenomation in a dog.

Science.gov (United States)

Padula, Andrew M; Winkel, Kenneth D

2016-05-01

This report describes a confirmed clinical case of tiger snake (Notechis scutatus) envenomation in a domestic dog that was successfully treated with a novel polyvalent camelid (alpaca; Llama pacos) antivenom. Samples collected from the dog were assayed for tiger snake venom (TSV) using a highly sensitive and specific ELISA. The TSV concentration in serum and urine at initial presentation was 365 ng/mL and 11,640 ng/mL respectively. At the time of initial presentation whole blood collected from the dog did not clot and the Prothrombin Time was abnormally increased (>300 s). Serum was also visibly hemolysed. The dog was administered antihistamine, dexamethasone and 4000 Units (sufficient to neutralise 40 mg of TSV) of a novel polyvalent alpaca antivenom diluted in 0.9% NaCl. At 4 h post-antivenom treatment the dog's clinical condition had improved markedly with serum TSV concentrations below the limit of detection (<0.015 ng/mL), consistent with complete binding of venom antigens by the alpaca antivenom. Coagulation parameters had begun to improve by 4 h and had fully normalised by 16 h post-antivenom. Venom concentrations in both serum and urine remained undetectable at 16 h post-antivenom. The dog made a complete recovery, without complications, suggesting that the alpaca-based antivenom is both clinically safe and effective. Copyright © 2016 Elsevier Ltd. All rights reserved.

Neuropeptide diversity and the regulation of social behavior in New World primates

Science.gov (United States)

French, Jeffrey A.; Taylor, Jack H.; Mustoe, Aaryn C.; Cavanaugh, Jon

2016-01-01

Oxytocin (OT) and vasopressin (AVP) are important hypothalamic neuropeptides that regulate peripheral physiology, and have emerged as important modulators of brain function, particularly in the social realm. OT structure and the genes that ultimately determine structure are highly conserved among diverse eutherian mammals, but recent discoveries have identified surprising variability in OT and peptide structure in New World monkeys (NWM), with five new OT variants identified to date. This review explores these new findings in light of comparative OT/AVP ligand evolution, documents coevolutionary changes in the oxytocin and vasopressin receptors (OTR and V1aR), and highlights the distribution of neuropeptidergic neurons and receptors in the primate brain. Finally, the behavioral consequences of OT and AVP in regulating NWM sociality are summarized, demonstrating important neuromodulatory effects of these compounds and OT ligand-specific influences in certain social domains. PMID:27020799

AIDS: new threat to the third world.

Science.gov (United States)

Heise, L

1988-01-01

Acquired immuneodeficiency syndrome (AIDS) threatens to have a catastrophic historical impact on the 3rd world, undermining decades of progress toward improved health and sustained economic development. By 1986, the World Health Organization (WHO) estimate between 5 and 10 million people worldwide were carriers. By 1990, WHO projects 50 to 100 million may be infected, leaving 15 to 30 million dead by 1995. The extent of AIDS cases in LDCs is most likely underreported as these countries already have limited access to health care. The infection rate could be 100 times higher in African cities than in the US as a whole. With an estimated 2 million infected, Africa is the hardest hit region in the world; Asia is the least affected with Japan having the highest number of reported cases at 43. Overall rate of transmission is likely to remain higher in the 3rd world for numerous reasons including the prevalence of sexually transmitted diseases, lack of money to screen blood for transfusions, high number of sexual partners due to socio-economic conditions, chronic exposure to viral and parasitic infections, and unhygienic conditions. Unlike developed nations, LDCs do not have the health care budgets to care for the opportunistic infections of AIDS patients. Therefore they often are subject to triage, passed over in favor of patients with curable diseases. AIDS provides an even greater threat as a multiplier of existing but dormant diseases such as tuberculosis. AIDS will undermine the decades of progress in maternal and child health and may soon be significant factor in the mother/child survival quotient. Some African cities report that 8 to 14% of women attending prenatal clinics test positive. Since it strikes the most productive age group--those between 20 and 49-- AIDS threatens to undermine the economies of LDCs at a time when most LDCsa are already struggling. Meeting the global challenge of AIDS will requre unprecedented international cooperation. The fact that both

Developing as new search engine and browser for libraries to search and organize the World Wide Web library resources

OpenAIRE

Sreenivasulu, V.

2000-01-01

Internet Granthalaya urges world wide advocates and targets at the task of creating a new search engine and dedicated browseer. Internet Granthalaya may be the ultimate search engine exclusively dedicated for every library use to search and organize the world wide web libary resources

Molecular Diversity between Salivary Proteins from New World and Old World Sand Flies with Emphasis on Bichromomyia olmeca, the Sand Fly Vector of Leishmania mexicana in Mesoamerica.

Science.gov (United States)

Abdeladhim, Maha; V Coutinho-Abreu, Iliano; Townsend, Shannon; Pasos-Pinto, Silvia; Sanchez, Laura; Rasouli, Manoochehr; B Guimaraes-Costa, Anderson; Aslan, Hamide; Francischetti, Ivo M B; Oliveira, Fabiano; Becker, Ingeborg; Kamhawi, Shaden; Ribeiro, Jose M C; Jochim, Ryan C; Valenzuela, Jesus G

2016-07-01

Sand fly saliva has been shown to have proteins with potent biological activities, salivary proteins that can be used as biomarkers of vector exposure, and salivary proteins that are candidate vaccines against different forms of leishmaniasis. Sand fly salivary gland transcriptomic approach has contributed significantly to the identification and characterization of many of these salivary proteins from important Leishmania vectors; however, sand fly vectors in some regions of the world are still neglected, as Bichromomyia olmeca (formerly known as Lutzomyia olmeca olmeca), a proven vector of Leishmania mexicana in Mexico and Central America. Despite the importance of this vector in transmitting Leishmania parasite in Mesoamerica there is no information on the repertoire of B. olmeca salivary proteins and their relationship to salivary proteins from other sand fly species. A cDNA library of the salivary glands of wild-caught B. olmeca was constructed, sequenced, and analyzed. We identified transcripts encoding for novel salivary proteins from this sand fly species and performed a comparative analysis between B. olmeca salivary proteins and those from other sand fly species. With this new information we present an updated catalog of the salivary proteins specific to New World sand flies and salivary proteins common to all sand fly species. We also report in this work the anti-Factor Xa activity of Lofaxin, a salivary anticoagulant protein present in this sand fly species. This study provides information on the first transcriptome of a sand fly from Mesoamerica and adds information to the limited repertoire of salivary transcriptomes from the Americas. This comparative analysis also shows a fast degree of evolution in salivary proteins from New World sand flies as compared with Old World sand flies.

From the Old to the New World of Nuclear Physics

Science.gov (United States)

Stuewer, Roger H.

Physicists passed from the Old to the New World of Nuclear Physics in the two decades between the first and second world wars. The transition occurred against the background of the Great War, the postwar hyperinflation in Germany and Austria, and the greatest intellection migrations in history after the Nazi Civil Service law of 1933, the Anschlussof Austria in March 1938, and the Fascist anti-Semitic laws that fall. It involved Rutherford's discovery of artificial disintegration, Pettersson and Kirsch's challenge of it, and the concomitant rise and fall of Rutherford's satellite model of the nucleus; Gamow's quantum-mechanical theory of alpha decay and his liquid-drop model of the nucleus; the discoveries of deuterium and the deuteron, neutron, and positron, and the inventions of the Cockcroft-Walton accelerator and the cyclotron; the influence of the seventh Solvay Conference; Joliot and Curie's discovery of artificial radioactivity; Pauli's neutrino hypothesis, Fermi's theory of beta decay, and his discovery of the efficacy of slow neutrons in producing nuclear reactions; Bohr's theory of the compound nucleus and Breit and Wigner's theory of neutron-nucleus resonances; and the discovery of nuclear fission, Meitner and Frisch's interpretation of it, and Bohr and Fermi revelation of both in America.

Digital Worlds as Sites of Belonging for Third Culture Kids: A New Literacies Perspective

Science.gov (United States)

Hannaford, Jeanette

2016-01-01

Literacies developed in digital worlds are part of the out-of-school experiences that students bring into their classrooms every day. This article, which draws from a multiple case study undertaken in an international school, calls on a sociocultural--new literacies approach to explore identity, discourse and space within the online practices of…

Invasion of Old World Phragmites australis in the New World: precipitation and temperature patterns combined with human influences redesign the invasive niche.

Science.gov (United States)

Guo, Wen-Yong; Lambertini, Carla; Li, Xiu-Zhen; Meyerson, Laura A; Brix, Hans

2013-11-01

After its introduction into North America, Euro-Asian Phragmites australis became an aggressive invasive wetland grass along the Atlantic coast of North America. Its distribution range has since expanded to the middle, south and southwest of North America, where invasive P. australis has replaced millions of hectares of native plants in inland and tidal wetlands. Another P. australis invasion from the Mediterranean region is simultaneously occurring in the Gulf region of the United States and some countries in South America. Here, we analysed the occurrence records of the two Old World invasive lineages of P. australis (Haplotype M and Med) in both their native and introduced ranges using environmental niche models (ENMs) to assess (i) whether a niche shift accompanied the invasions in the New World; (ii) the role of biologically relevant climatic variables and human influence in the process of invasion; and (iii) the current potential distribution of these two lineages. We detected local niche shifts along the East Coast of North America and the Gulf Coast of the United States for Haplotype M and around the Mississippi Delta and Florida of the United States for Med. The new niche of the introduced Haplotype M accounts for temperature fluctuations and increased precipitation. The introduced Med lineage has enlarged its original subtropical niche to the tropics-subtropics, invading regions with a high annual mean temperature (> ca. 10 °C) and high precipitation in the driest period. Human influence is an important factor for both niches. We suggest that an increase in precipitation in the 20th century, global warming and human-made habitats have shaped the invasive niches of the two lineages in the New World. However, as the invasions are ongoing and human and natural disturbances occur concomitantly, the future distribution ranges of the two lineages may diverge from the potential distribution ranges detected in this study. © 2013 John Wiley & Sons Ltd.

First New World Primate Papillomavirus Identification in the Atlantic Forest, Brazil: Alouatta guariba papillomavirus 1.

Science.gov (United States)

Silvestre, Rodrigo Vellasco Duarte; de Souza, Alex Junior Souza; Júnior, Edivaldo Costa Sousa; Silva, Allan Kaio; de Mello, Wyller Alencar; Nunes, Marcio Roberto T; Júnior, João Lídio S G V; Cardoso, Jedson Ferreira; de Vasconcelos, Janaina Mota; de Oliveira, Layanna Freitas; da Silva, Sandro Patroca; da Silva, Adriana Marques J; Fries, Brigida Gomes; Summa, Maria Eugênia L; de Sá, Lilian Rose M

2016-08-18

We report here the complete genome sequence of the first papillomavirus detected in a New World primate, howler monkey, Alouatta guariba clamitans papillomavirus 1 (AgPV1), from the Atlantic Forest in São Paulo State, Brazil. Copyright © 2016 Silvestre et al.

Economic impact of eradicating the New World screw-worm (Cochliomyia hominivorax) from Jamaica

International Nuclear Information System (INIS)

Vo, Trang T.

2000-01-01

The purpose of the study is to assess the economic feasibility of eradicating the New World screw-worm (NWS), Cochliomyia hominivorax Coquerel, from Jamaica. The endemic presence of the NWS in Jamaica has caused the livestock sector to incur recurrent economic costs and losses. Eradication of the pest utilising the environmentally-benign sterile insect technique (SIT) has proved technologically feasible on other islands and other parts of the world. Based on these successful experiences, the proposed project to eradicate the NWS from Jamaica is expected to be similarly effective in eliminating the pest from Jamaica in a relatively short period of time. The elimination of the pest from the Caribbean would lessen the significant risk of re-infestation of eradicated areas and pest-free countries in the region

Can BRICS Build Ivory Towers of Excellence? Giving New Meaning to World-Class Universities

Science.gov (United States)

David, Solomon Arulraj; Motala, Shireen

2017-01-01

This paper aims to map the landscape of higher education transformation in the BRICS (Brazil, Russia, India, China and South Africa) nations while exploring the status of BRICS nations in some of the global university rankings and analysing their potential to give new meaning to notions such as excellent and world-class universities. The study…

Combining fossil and molecular data to date the diversification of New World Primates.

Science.gov (United States)

Schrago, C G; Mello, B; Soares, A E R

2013-11-01

Recent methodological advances in molecular dating associated with the growing availability of sequence data have prompted the study of the evolution of New World Anthropoidea in recent years. Motivated by questions regarding historical biogeography or the mode of evolution, these works aimed to obtain a clearer scenario of Platyrrhini origins and diversification. Although some consensus was found, disputed issues, especially those relating to the evolutionary affinities of fossil taxa, remain. The use of fossil taxa for divergence time analysis is traditionally restricted to the provision of calibration priors. However, new analytical approaches have been developed that incorporate fossils as terminals and, thus, directly assign ages to the fossil tips. In this study, we conducted a combined analysis of molecular and morphological data, including fossils, to derive the timescale of New World anthropoids. Differently from previous studies that conducted total-evidence analysis of molecules and morphology, our approach investigated the morphological clock alone. Our results corroborate the hypothesis that living platyrrhines diversified in the last 20 Ma and that Miocene Patagonian fossils compose an independent evolutionary radiation that diversified in the late Oligocene. When compared to the node ages inferred from the molecular timescale, the inclusion of fossils augmented the precision of the estimates for nodes constrained by the fossil tips. We show that morphological data can be analysed using the same methodological framework applied in relaxed molecular clock studies. © 2013 The Authors. Journal of Evolutionary Biology © 2013 European Society For Evolutionary Biology.

The Hunt for Planet X New Worlds and the Fate of Pluto

CERN Document Server

Schilling, Govert

2009-01-01

"The Hunt for Planet X is a fascinating tale by one of the world's premier astronomy writers. Govert Schilling is not only scrupulously accurate, he writes beautifully as well." Stephen P. Maran, Author of "Astronomy for Dummies" and Press Officer, American Astronomical Society "The Hunt for Planet X is an adventure story or, more accurately, a series of adventure stories. Schilling tells them well, capturing both the science and the people involved. It starts with the classics: Uranus, Neptune and Pluto; and moves all over the solar system as ground-based astronomers and space scientists pour over measurements and observations to try to understand the worlds around us. Current debates about the Pioneer Anomaly and the definition of what is a planet make the book current as well as a good history." Dr. Louis Friedman, Executive Director, The Planetary Society "This exciting tale of the centuries-old search for new planets in the solar system reads like a thriller. It is an adventure packed with fierce competi...

Adapting Traditional Ideas for a New Reality: Cosmographers and Physicians Updating Astrology to Encompass the New World.

Science.gov (United States)

Lanuza Navarro, Tayra M C

2016-08-01

This paper aims to demonstrate that astrology was one of the disciplines that most strongly experienced the process that led European natural philosophers, once they were confronted with the nature of the New World, to recognise that previous knowledge was not as complete or absolute as previously assumed, and that the content of several disciplines had to be renewed, both epistemologically and methodologically. This paper focuses on the work by the cosmographer Henrico Martinez, Repertorio de los tiempos (1606), in which he established the astrological influences specific to Mexico, and the work Sitio, naturatezay propiedades de la Ciudad de Mexico (1618) by the physician Diego Cisneros, who refuted Martinez's astrology for Mexico and created his own instructions for the use of astrology in the practice of medicine in New Spain.

The tempo and mode of New World monkey evolution and biogeography in the context of phylogenomic analysis.

Science.gov (United States)

Jameson Kiesling, Natalie M; Yi, Soojin V; Xu, Ke; Gianluca Sperone, F; Wildman, Derek E

2015-01-01

The development and evolution of organisms is heavily influenced by their environment. Thus, understanding the historical biogeography of taxa can provide insights into their evolutionary history, adaptations and trade-offs realized throughout time. In the present study we have taken a phylogenomic approach to infer New World monkey phylogeny, upon which we have reconstructed the biogeographic history of extant platyrrhines. In order to generate sufficient phylogenetic signal within the New World monkey clade, we carried out a large-scale phylogenetic analysis of approximately 40 kb of non-genic genomic DNA sequence in a 36 species subset of extant New World monkeys. Maximum parsimony, maximum likelihood and Bayesian inference analysis all converged on a single optimal tree topology. Divergence dating and biogeographic analysis reconstruct the timing and geographic location of divergence events. The ancestral area reconstruction describes the geographic locations of the last common ancestor of extant platyrrhines and provides insight into key biogeographic events occurring during platyrrhine diversification. Through these analyses we conclude that the diversification of the platyrrhines took place concurrently with the establishment and diversification of the Amazon rainforest. This suggests that an expanding rainforest environment rather than geographic isolation drove platyrrhine diversification. Copyright © 2014 Elsevier Inc. All rights reserved.

Mother of a New World? Stereotypical Representations of Black Women in Three Postapocalyptic Films

Directory of Open Access Journals (Sweden)

Karima K. Jeffrey

2014-06-01

Full Text Available This essay explores three cinematic representations of Black matriarchs who play prophetic roles in redeeming humanity in the midst of apocalyptic change: Ika (Quest for Fire, Kee (Children of Men, and The Oracle (The Matrix trilogy. Not only do these courageous women resist the politics of domination, rebelling against a dying status quo, but they "give birth" to the leaders needed to rebuild a world in chaos and decay. One film ends with a pregnant woman rubbing her belly as she stands on the precipice of evolutionary change; another positions a mother and newborn adrift, waiting to be found by leaders of a new world order; in the third, a character sacrifices herself to empower resistance fighters with ideas and the means to choose their survival in a postapocalyptic world. Defying the politics of an annihilating patriarchy, these women portend a return to a naturally evolving world. However, despite their powerful influence, they can be understood, problematically, as modern-day reinventions of Black female stereotypes—Ika as Jezebel, Kee as Hagar, the Oracle as Mammy—because they, and the indices for understanding their roles in the community, are wedded to White patriarchs and to their own gendered functions as nurturing or sexual(ized beings.

Nutrition: the new world disorder.

Science.gov (United States)

Cannon, Geoffrey

2002-01-01

Scale up 'we are what we eat' and nutrition is revealed as an aspect of world governance. The quality and nature of food systems has always tended to determine not only the health and welfare but also the fate of nations. The independence of nations depends on their development of their own human and natural resources, including food systems, which, if resilient, are indigenous, traditional, or evolved over time to climate, terrain and culture. Rapid adoption of untested or foreign food systems is hazardous not only to health, but also to security and sovereignty. Immediate gain may cause permanent loss. Dietary guidelines that recommend strange foods are liable to disrupt previous established food cultures. Since the 1960s the 'green revolution' has increased crop yield, and has also accelerated the exodus of hundreds of millions of farmers and their families from the land into lives of misery in mega-cities. This is a root cause of increased global inequity, instability and violence. 'Free trade' of food, in which value is determined by price, is imposed by dominant governments in alliance with industry when they believe they can thereby control the markets. The World Trade Organization and other agencies coordinate the work of transnational corporations that are the modern equivalents of the East India companies. Scientists should consider the wider dimensions of their work, nutrition scientists not least, because of the key place of food systems in all societies.

The UN Charter and the New World Order

Directory of Open Access Journals (Sweden)

Lidiya Evgenievna Grishaeva

2015-12-01

Full Text Available The article shows the importance of the adoption of the UN Charter. The rules and principles of international law embodied in the Charter of the United Nations, form the basis of modern law and order, the preservation of peace and allow to overcome international conflicts. The United Nations is a multilateral international organization and the efficiency of its operations affect the consistency of the positions of the Member States, the degree of interaction in the UN Security Council. The credibility of the UN and its legitimacy, breadth of competence and representativeness allow staff to play an indispensable role in global politics, economic and humanitarian cooperation. In order to maintain the stability of the present world order is necessary to keep the preservation of the basic foundations of international law, the improvement of international legal categories in order to eliminate double standards in law enforcement. Cooperation in the framework of the UN is necessary in solving regional conflicts, countering new challenges and threats to international security. On this depends the effectiveness of the United Nations.

Phylogeny and palaeoecology of Polyommatus blue butterflies show Beringia was a climate-regulated gateway to the New World.

Science.gov (United States)

Vila, Roger; Bell, Charles D; Macniven, Richard; Goldman-Huertas, Benjamin; Ree, Richard H; Marshall, Charles R; Bálint, Zsolt; Johnson, Kurt; Benyamini, Dubi; Pierce, Naomi E

2011-09-22

Transcontinental dispersals by organisms usually represent improbable events that constitute a major challenge for biogeographers. By integrating molecular phylogeny, historical biogeography and palaeoecology, we test a bold hypothesis proposed by Vladimir Nabokov regarding the origin of Neotropical Polyommatus blue butterflies, and show that Beringia has served as a biological corridor for the dispersal of these insects from Asia into the New World. We present a novel method to estimate ancestral temperature tolerances using distribution range limits of extant organisms, and find that climatic conditions in Beringia acted as a decisive filter in determining which taxa crossed into the New World during five separate invasions over the past 11 Myr. Our results reveal a marked effect of the Miocene-Pleistocene global cooling, and demonstrate that palaeoclimatic conditions left a strong signal on the ecology of present-day taxa in the New World. The phylogenetic conservatism in thermal tolerances that we have identified may permit the reconstruction of the palaeoecology of ancestral organisms, especially mobile taxa that can easily escape from hostile environments rather than adapt to them. This journal is © 2011 The Royal Society

mtDNA variation in the Yanomami: evidence for additional New World founding lineages.

Science.gov (United States)

Easton, R D; Merriwether, D A; Crews, D E; Ferrell, R E

1996-07-01

Native Americans have been classified into four founding haplogroups with as many as seven founding lineages based on mtDNA RFLPs and DNA sequence data. mtDNA analysis was completed for 83 Yanomami from eight villages in the Surucucu and Catrimani Plateau regions of Roraima in northwestern Brazil. Samples were typed for 15 polymorphic mtDNA sites (14 RFLP sites and 1 deletion site), and a subset was sequenced for both hypervariable regions of the mitochondrial D-loop. Substantial mitochondrial diversity was detected among the Yanomami, five of seven accepted founding haplotypes and three others were observed. Of the 83 samples, 4 (4.8%) were lineage B1, 1 (1.2%) was lineage B2, 31 (37.4%) were lineage C1, 29 (34.9%) were lineage C2, 2 (2.4%) were lineage D1, 6 (7.2%) were lineage D2, 7 (8.4%) were a haplotype we designated "X6," and 3 (3.6%) were a haplotype we designated "X7." Sequence analysis found 43 haplotypes in 50 samples. B2, X6, and X7 are previously unrecognized mitochondrial founding lineage types of Native Americans. The widespread distribution of these haplotypes in the New World and Asia provides support for declaring these lineages to be New World founding types.

Neoliberalism with a Feminist Face: Crafting a New Hegemony at the World Bank

OpenAIRE

Prügl Elisabeth

2016-01-01

Neoliberalism has been discredited as a result of proliferating crises (financial ecological care) and mounting inequality. This paper examines the growing research on gender at the World Bank as a site for the construction of a new hegemonic consensus around neoliberalism. Drawing on a computer assisted inductive analysis of thirty four Bank publications on gender since 2001 the paper documents Bank efforts to establish a positive relationship between gender equality and growth; shows the ex...

Learning Experience with Virtual Worlds

Science.gov (United States)

Wagner, Christian

2008-01-01

Virtual worlds create a new opportunity to enrich the educational experience through media-rich immersive learning. Virtual worlds have gained notoriety in games such as World of Warcraft (WoW), which has become the most successful online game ever, and in "general purpose" worlds, such as Second Life (SL), whose participation levels (more than 10…

Brave new worlds for nuclear medicine

International Nuclear Information System (INIS)

Cassels, Derek.

1979-01-01

This article of a general nature discusses the radioisotopes produced by the Atomic Energy of Canada Limited Commercial Products Division. Cobalt treatment units are being used successfully throughout the world and cobalt units are becoming increasingly important in sterilizing medical supplies. This technology may be extended to kill bacteria and insects responsible for food spoilage. (TI)

Global Poverty and the New Bottom Billion: Three-Quarters of the World?s Poor Live in Middle-Income Countries

OpenAIRE

Andy Sumner

2011-01-01

In 1990, 93 per cent of the world?s poor people lived in poor countries?that is, low-income countries (LICs). For 2007?2008, our estimates suggest three things. First, three-quarters of the world?s poor, or almost 1 billion poor people, now live in middle-income countries (MICs). Second, just a quarter of the world?s poor live in 39 LICs. Third, in contrast to earlier estimates that a third of the poor live in fragile states, our estimate is about 23 per cent if one takes the broadest definit...

A new fossil from the mid-Paleocene of New Zealand reveals an unexpected diversity of world's oldest penguins

Science.gov (United States)

Mayr, Gerald; De Pietri, Vanesa L.; Paul Scofield, R.

2017-04-01

We describe leg bones of a giant penguin from the mid-Paleocene Waipara Greensand of New Zealand. The specimens were found at the type locality of Waimanu manneringi and together with this species they constitute the oldest penguin fossils known to date. Tarsometatarsus dimensions indicate a species that reached the size of Anthropornis nordenskjoeldi, one of the largest known penguin species. Stem group penguins therefore attained a giant size very early in their evolution, with this gigantism existing for more than 30 million years. The new fossils are from a species that is phylogenetically more derived than Waimanu, and the unexpected coexistence of Waimanu with more derived stem group Sphenisciformes documents a previously unknown diversity amongst the world's oldest penguins. The characteristic tarsometatarsus shape of penguins evolved early on, and the significant morphological disparity between Waimanu and the new fossil conflicts with recent Paleocene divergence estimates for penguins, suggesting an older, Late Cretaceous, origin.

A new fossil from the mid-Paleocene of New Zealand reveals an unexpected diversity of world's oldest penguins.

Science.gov (United States)

Mayr, Gerald; De Pietri, Vanesa L; Paul Scofield, R

2017-04-01

We describe leg bones of a giant penguin from the mid-Paleocene Waipara Greensand of New Zealand. The specimens were found at the type locality of Waimanu manneringi and together with this species they constitute the oldest penguin fossils known to date. Tarsometatarsus dimensions indicate a species that reached the size of Anthropornis nordenskjoeldi, one of the largest known penguin species. Stem group penguins therefore attained a giant size very early in their evolution, with this gigantism existing for more than 30 million years. The new fossils are from a species that is phylogenetically more derived than Waimanu, and the unexpected coexistence of Waimanu with more derived stem group Sphenisciformes documents a previously unknown diversity amongst the world's oldest penguins. The characteristic tarsometatarsus shape of penguins evolved early on, and the significant morphological disparity between Waimanu and the new fossil conflicts with recent Paleocene divergence estimates for penguins, suggesting an older, Late Cretaceous, origin.

A revision of the new world species of Polytrichophora Cresson and Facitrichophora, new genus (Diptera, Ephydridae

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Wayne Mathis

2012-10-01

Full Text Available The New World species of Polytrichophora Cresson and Fascitrichophora new genus, are revised. Fifteen new species are described (type locality in parenthesis: Fascitrishophora atrella sp. n. (Costa Rica. Guanacaste: Murciélago [10°56.9’N, 85°42.5’W; sandy mud flats around mangrove inlet], F. carvalhorum sp.n. (Brazil. São Paulo: Praia Puruba [23°21’S, 44°55.6’W; beach], F. manza sp. n. (Trinidad and Tobago. Trinidad. St. Andrew: Lower Manzanilla (12 km S; 10°24.5’N, 61°01.5’W, bridge over Nariva River, F. panama sp. n. (Panama. Darien: Garachine [8°04’N, 78°22’W], Polytrichophora adarca sp. n. (Barbados. Christ Church: Graeme Hall Nature Sanctuary [13°04.2’N, 59°34.7’W; swamp], P. arnaudorum sp. n. (Mexico. Baja California. San Felipe [31°01.5’N, 114°50.4’W], P. barba sp. n. (Cuba. Sancti Spiritus: Topes de Collantes [21°54.4’N, 80°01.4’W, 670 m], P. flavella sp. n. (Peru. Madre de Dios: Rio Manu, Pakitza [11°56.6’S, 71°16.9’W; 250 m], P. marinoniorum sp. n. (Brazil. Paraná: Antonina [25°28.4’S, 48°40.9’W; mangal], P. rostra sp. n. (Peru. Madre de Dios: Rio Manu, Pakitza [11°56.6’S, 71°16.9’W; 250 m], P. sinuosa sp. n. (Trinidad and Tobago. Trinidad. St. Andrew: Lower Manzanilla [12 km S; 10°24’N, 61°02’W], P. mimbres sp. n. (United States. New Mexico. Grant: Mimbres River [New Mexico Highway 61 & Royal John Mine Road; 32°43.8’N, 107°52’W; 1665 m], P. salix sp. n. (United States. Alaska. Matanuska-Susitna: Willow Creek [61°46.1’N, 150°04.2’W; 50 m], P. sturtevantorum sp. n. (United States. Tennessee. Shelby: Meeman Shelby State Park [Mississippi River; 35°20.4’N, 90°2.1’W; 98 m], P. prolata sp. n. (Belize. Stann Creek: Cockscomb Basin Wildlife Sanctuary [16°45’N, 88°30’W]. All known New World species of both genera are described with an emphasis on structures of the male terminalia, which are fully illustrated. Detailed locality data and distribution

Globalization of health insecurity: the World Health Organization and the new International Health Regulations.

Science.gov (United States)

Aginam, Obijiofor

2006-12-01

The transnational spread of communicable and non-communicable diseases has opened new vistas in the discourse of global health security. Emerging and re-emerging pathogens, according to exponents of globalization of public health, disrespect the geo-political boundaries of nation-states. Despite the global ramifications of health insecurity in a globalizing world, contemporary international law still operates as a classic inter-state law within an international system exclusively founded on a coalition of nation-states. This article argues that the dynamic process of globalization has created an opportunity for the World Health Organization to develop effective synergy with a multiplicity of actors in the exercise of its legal powers. WHO's legal and regulatory strategies must transform from traditional international legal approaches to disease governance to a "post-Westphalian public health governance": the use of formal and informal sources from state and non-state actors, hard law (treaties and regulations) and soft law (recommendations and travel advisories) in global health governance. This article assesses the potential promise and problems of WHO's new International Health Regulations (IHR) as a regulatory strategy for global health governance and global health security.

World History Workshop (1983).

Science.gov (United States)

1984-10-01

history appeared tenuous. While the study of American history was viewed as necessary to "indoctrinate kids ," world history is unable to make such a...world" which is hard to avoid in world history, where one examines China in 1500, China in 1800, and so on. A pedagogical goal in the new course was to...the historian to make intelligent decisions about what information he is going to talk about. Viewing world history as a scenario also has a pedagogic

MAJOR PROJECTS THAT INFLUENCE WORLD TRADE

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GEORGE CORNEL DUMITRESCU

2014-11-01

Full Text Available In 1869, with the opening of the Suez Canal, world trade entered a new era of development. The commercial routes linking the Far East to the western countries were shortened considerably as compared to the maritime corridor around the Cape of Good Hope. In 1914, the opening of the Panama Canal sealed the new deal in world trade, opening for business the shortest commercial routes around the world. After 145 years from the inauguration of the Suez Canal, world trade is on the eve of a new expansion. Two major projects: the expansion of both the Suez and Panama canals, planned to be completed in the next two years, will double their transit capacity. This paper does a comparative analysis of these two strategic projects, underlining the main benefits for Egypt, Panama and world trade, based on the available statistical data, reports and literature in the field.

The Development of Rocketry Capability in New Zealand—World Record Rocket and First of Its Kind Rocketry Course

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George Buchanan

2015-02-01

Full Text Available The University of Canterbury has developed a rocket research group, UC Rocketry, which recently broke the world altitude record for an I-class motor (impulse of 320–640 Ns and has run a rocketry course for the first time in New Zealand. This paper discusses the development and results of the world record rocket “Milly” and details all the fundamental elements of the rocketry final year engineering course, including the manufacturing processes, wind tunnel testing, avionics, control and the final rocket launch of “Smokey”. The rockets Milly and Smokey are an example of the design, implementation and testing methodologies that have significantly contributed to research and graduates for New Zealand’s space program.

Identification of New World Quails Susceptible to Infection with Avian Leukosis Virus Subgroup J

Czech Academy of Sciences Publication Activity Database

Plachý, Jiří; Reinišová, Markéta; Kučerová, Dana; Šenigl, Filip; Stepanets, Volodymyr; Hron, Tomáš; Trejbalová, Kateřina; Elleder, Daniel; Hejnar, Jiří

2017-01-01

Roč. 91, č. 3 (2017), č. článku e02002. ISSN 0022-538X R&D Projects: GA ČR GA13-30983S; GA MŠk LO1419 Institutional support: RVO:68378050 Keywords : ALV-J * antiretroviral resistance * Na+/H+ exchanger * New World quail * retroviral receptor Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Virology Impact factor: 4.663, year: 2016

Genetic Diversity in Natural Populations of New World Leishmania

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Cupolillo Elisa

1998-01-01

Full Text Available Our results have shown the wide diversity of parasites within New World Leishmania. Biochemical and molecular characterization of species within the genus has revealed that much of the population heterogeneity has a genetic basis. The source of genetic diversity among Leishmania appears to arise from predominantly asexual, clonal reproduction, although occasional bouts of sexual reproduction can not be ruled out. Genetic variation is extensive with some clones widely distributed and others seemingly unique and localized to a particular endemic focus. Epidemiological studies of leishmaniasis has been directed to the ecology and dynamics of transmission of Leishmania species/variants, particularly in localized areas. Future research using molecular techniques should aim to identify and follow Leishmania types in nature and correlate genetic typing with important clinical characteristics such as virulence, pathogenicity, drug resistance and antigenic variation. The epidemiological significance of such variation not only has important implications for the control of the leishmaniases, but would also help to elucidate the evolutionary biology of the causative agents.

Charting the new world order: proceedings of the 15. CERI international oil and gas markets conference

International Nuclear Information System (INIS)

1996-10-01

The 15th International Oil and Gas Markets Conference, organized by the Canadian Energy Research Institute (CERI) and held in Calgary, AB, provided a wide variety of opportunities for discussion of the global oil and gas market outlook, international oil and gas market strategies and corporate planning in the new world order, competition for investments, the re-emergence of the geopolitics of energy, energy in the Americas, international gas market strategies, and the financing of Canadian international operations. More than 100 delegates from around the world attended the conference to hear some 20 presentations. refs., tabs., figs

WWW.Cell Biology Education: Using the World Wide Web to Develop a New Teaching Topic

Science.gov (United States)

Blystone, Robert V.; MacAlpine, Barbara

2005-01-01

"Cell Biology Education" calls attention each quarter to several Web sites of educational interest to the biology community. The Internet provides access to an enormous array of potential teaching materials. In this article, the authors describe one approach for using the World Wide Web to develop a new college biology laboratory exercise. As a…

In the Best Interests of Youth or Neoliberalism? The World Bank and the New Global Youth Empowerment Project

Science.gov (United States)

Sukarieh, Mayssoun; Tannock, Stuart

2008-01-01

Youth, and youth employment especially, have jumped to the forefront of the international development agenda, driven by new funding and reporting priorities of the World Bank and allied international and national aid organisations. Despite the seductive rhetoric of youth empowerment, however, we argue that the new turn to youth serves primarily to…

New World feline APOBEC3 potently controls inter-genus lentiviral transmission.

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Konno, Yoriyuki; Nagaoka, Shumpei; Kimura, Izumi; Yamamoto, Keisuke; Kagawa, Yumiko; Kumata, Ryuichi; Aso, Hirofumi; Ueda, Mahoko Takahashi; Nakagawa, So; Kobayashi, Tomoko; Koyanagi, Yoshio; Sato, Kei

2018-04-10

The apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) gene family appears only in mammalian genomes. Some A3 proteins can be incorporated into progeny virions and inhibit lentiviral replication. In turn, the lentiviral viral infectivity factor (Vif) counteracts the A3-mediated antiviral effect by degrading A3 proteins. Recent investigations have suggested that lentiviral vif genes evolved to combat mammalian APOBEC3 proteins, and have further proposed that the Vif-A3 interaction may help determine the co-evolutionary history of cross-species lentiviral transmission in mammals. Here we address the co-evolutionary relationship between two New World felids, the puma (Puma concolor) and the bobcat (Lynx rufus), and their lentiviruses, which are designated puma lentiviruses (PLVs). We demonstrate that PLV-A Vif counteracts the antiviral action of APOBEC3Z3 (A3Z3) of both puma and bobcat, whereas PLV-B Vif counteracts only puma A3Z3. The species specificity of PLV-B Vif is irrespective of the phylogenic relationships of feline species in the genera Puma, Lynx and Acinonyx. We reveal that the amino acid at position 178 in the puma and bobcat A3Z3 is exposed on the protein surface and determines the sensitivity to PLV-B Vif-mediated degradation. Moreover, although both the puma and bobcat A3Z3 genes are polymorphic, their sensitivity/resistance to PLV Vif-mediated degradation is conserved. To the best of our knowledge, this is the first study suggesting that the host A3 protein potently controls inter-genus lentiviral transmission. Our findings provide the first evidence suggesting that the co-evolutionary arms race between lentiviruses and mammals has occurred in the New World.

Genomic characterization of H14 subtype influenza A viruses in New World waterfowl and experimental infectivity in mallards Anas platyrhynchos

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Ramey, Andy M.; Poulson, Rebecca L.; Gonzalez-Reiche, Ana S.; Perez, Daniel R.; Stalknecht, David E.; Brown, Justin D.

2014-01-01

Recent repeated isolation of H14 hemagglutinin subtype influenza A viruses (IAVs) in the New World waterfowl provides evidence to suggest that host and/or geographic ranges for viruses of this subtype may be expanding. In this study, we used genomic analyses to gain inference on the origin and evolution of H14 viruses in New World waterfowl and conducted an experimental challenge study in mallards (Anas platyrhynchos) to evaluate pathogenicity, viral replication, and transmissibility of a representative viral strain in a natural host species. Genomic characterization of H14 subtype IAVs isolated from New World waterfowl, including three isolates sequenced specifically for this study, revealed high nucleotide identity among individual gene segments (e.g. ≥95% shared identity among H14 HA gene segments). In contrast, lower shared identity was observed among internal gene segments. Furthermore, multiple neuraminidase subtypes were observed for H14 IAVs isolated in the New World. Gene segments of H14 viruses isolated after 2010 shared ancestral genetic lineages with IAVs isolated from wild birds throughout North America. Thus, genomic characterization provided evidence for viral evolution in New World waterfowl through genetic drift and genetic shift since purported introduction from Eurasia. In the challenge study, no clinical disease or lesions were observed among mallards experimentally inoculated with A/blue-winged teal/Texas/AI13-1028/2013(H14N5) or exposed via contact with infected birds. Titers of viral shedding for mallards challenged with the H14N5 IAV were highest at two days post-inoculation (DPI); however shedding was detected up to nine DPI using cloacal swabs. The distribution of viral antigen among mallards infected with H14N5 IAV was largely restricted to enterocytes lining the villi in the lower intestinal tract and in the epithelium of the bursa of Fabricius. Characterization of the infectivity of A/blue-winged teal/Texas/AI13-1028/2013(H14N5) in

Neurology in a globalizing world: World Congress of Neurology, Vienna, 2013.

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Hachinski, Vladimir

2013-06-11

The World Congress of Neurology (figure 1) theme "Neurology in a Globalizing World" acknowledges that science and increasingly medicine and neurology are becoming globalized. The best way to manage change is to shape it. It is becoming increasingly clear that brain diseases, particularly stroke and dementia, are projected to rise at a rate that could overwhelm our clinics and hospitals. Hence a new emphasis on prevention and the need to work across disciplines beyond our traditional roles. Neurologists are the guardians of the brain and need to take the lead role in advancing new approaches in stemming the tide of neurologic diseases.

Thematic Plan for the Sterile Insect Technique for Old and New World Screwworm

International Nuclear Information System (INIS)

1998-01-01

Objective: To support livestock development programmes aiming at controlling or eradicating key insect pests. This involves the application of the sterile insect technique (SIT) into area wide integrated pest management and eradication systems. The sustainability of eradication activities has been demonstrated for a number of insect pests under various national settings where the application of SIT has produced significant impact on socio-economic development, in terms of both cost-savings and environmental quality. In line with the TC strategy, this thematic plan reviews best practices and experience gained in field operations, identifies stakeholders and common objectives in New World Screwworm, Cochliomya hominivorax (NWS) and Old World Screwworm, Chrysomya bezziana (OWS), control and outlines a strategy for implementing integrated pest control programmes at the regional, sub-regional and national level. Synergies are sought with partner organisations to expand the knowledge base and capabilities for SIT based pest control activities and to strengthen TCDC.

Collection and analysis of peritoneal fluid from healthy llamas and alpacas.

Science.gov (United States)

Cebra, Christopher K; Tornquist, Susan J; Reed, Shannon K

2008-05-01

To describe a technique for abdominocentesis in camelids and report peritoneal fluid biochemical and cytologic findings from healthy llamas and alpacas. Prospective study. Animals-17 adult llamas and 5 adult alpacas. Right paracostal abdominocentesis was performed. Peritoneal fluid was collected by gravity flow into tubes containing potassium-EDTA for cell count and cytologic evaluation and lithium heparin for biochemical analysis. Blood samples were collected via jugular venipuncture into heparinized tubes at the same time. Cytologic components were quantified. Fluid pH and concentrations of total carbon dioxide, sodium, potassium, chloride, lactate, and glucose were compared between peritoneal fluid and venous blood. All but 3 camelids had peritoneal fluid cell counts of or = 2.5 g/dL. Peritoneal fluid of camelids generally contained slightly less glucose, lactate, and sodium and roughly equal concentrations of potassium and chloride as venous blood. Peritoneal fluid was collected safely from healthy camelids. Compared with blood, peritoneal fluid usually had a low cell count and protein concentration, but some individuals had higher values. Electrolyte concentrations resembled those found in blood. High cell counts and protein concentrations found in peritoneal fluid of some healthy camelids may overlap with values found in diseased camelids, complicating interpretation of peritoneal fluid values.

The World Soil Museum: education and advocacy on soils of the world

Science.gov (United States)

Mantel, Stephan; Land, Hiske

2013-04-01

The World Soil Museum (WSM) in Wageningen, is part of ISRIC World Soil Information and was founded in 1966 on request of the United Nations Educational, Scientific and Cultural Organization (UNESCO) and the International Soil Science Society. The World Soil Museum has a collection of over 1100 soil profiles from more than 70 countries. This soil profiles are vertical sections and show the composition, layering and structure of the soil. The collection is unique in the world and includes a significant number of soil profiles from the Netherlands. The Dutch soil collection is important for serving broader visitor groups, as some visitors, such as secondary school classes, are specifically interested in the Dutch landscape and soils. Broadly speaking, the World Soil Museum has five functions: (i) education and courses, (ii) research, (iii) information and edutainment, (iv) social function, and (v) a real museum function (Art). The World Soil Museum (World Soil Museum) is well known in national and international circles soil and the English name has almost 1,000 references on the Internet. The World Soil Museum is visited by about 1000 people a year, mainly university and college students from Western Europe. Other visitor groups that have found their way to the museum are students from disciplines broader then soil science, such as geography and rural development. Secondary school classes visit the museum for geography classes. The uniqueness and the value of the collection of soil profiles (soil monoliths) and associated collections, such as soil samples, hand pieces, thin sections, slides, is emphasized by the fact ISRIC is the only World Data Centre for Soils (WDC-Soils) within the World Data System of the International Council of Science (ICSU). The collection provides an insight in and overview of the diversity of soils in the world, their properties and their limitations and possibilities for use. A new building is under construction for the WSM, which is

The subspecific characters and distribution of the New World Skimmers - Rynchops nigra The subspecific characters and distribution of the New World Skimmers - Rynchops nigra

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Wetmore Alexander

1944-09-01

Full Text Available The distribution of the forms of the New World rayador, or skimmer, Rynchops nigra, and the characters that mark the geographic races, have been matters of interest to me for a number of years, an interest heightened by recent discussions in current literature of the identity of the birds found on the Pacific coast of Mexico, and far to the south in Chile. Investigation into these matters with the material available in the National Museum not being conclusive, specimens from Mexico and the West Indies southward to Argentina and Chile in other large collections in the United states have been assembled through the courtesy of Dr. Robert Cushman Murphy of the American Museum of Natural History, James l.. Peters of the Museum of Comparative Zoology,W. E. C. Todd of the Carnegie Museum, and Dr. Karl P. Schmidt of the Field Museum of Natural History. I have also to thank Dr. Alden H. Miller for the use of one specimen from Chubut in the Museum of Vertebrate Zoology, and Dean Amadon for certain notes on this group of birds that he had assembled.The distribution of the forms of the New World rayador, or skimmer, Rynchops nigra, and the characters that mark the geographic races, have been matters of interest to me for a number of years, an interest heightened by recent discussions in current literature of the identity of the birds found on the Pacific coast of Mexico, and far to the south in Chile. Investigation into these matters with the material available in the National Museum not being conclusive, specimens from Mexico and the West Indies southward to Argentina and Chile in other large collections in the United states have been assembled through the courtesy of Dr. Robert Cushman Murphy of the American Museum of Natural History, James l.. Peters of the Museum of Comparative Zoology,W. E. C. Todd of the Carnegie Museum, and Dr. Karl P. Schmidt of the Field Museum of Natural History. I have also to thank Dr. Alden H. Miller for the use of one specimen

A Psicologia no novo contexto mundial Psychology in the new world context

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Carla Faria Leitão

2003-12-01

Full Text Available Profundas alterações no mundo contemporâneo criaram um novo contexto de produção científica, caracterizado pela desconstrução de antigas teorias e pela construção de uma nova rede de conhecimentos. Neste artigo, analisamos algumas teorias recentemente desenvolvidas nas ciências sociais e na filosofia que compõem esta rede: as teorias pós-modernas, as teorias da modernização reflexiva e a teoria da Revolução da Tecnologia da Informação. Visamos com isto munir os psicólogos de conhecimentos advindos de outros campos disciplinares que sirvam como ponto de partida para a análise das mudanças subjetivas introduzidas pelo novo cenário mundial. Argumentamos que a psicologia ainda observa o homem contemporâneo a partir de categorias tradicionais, desconsiderando que transformações sociais profundas geram impactos psicológicos não menos profundos e dificilmente captáveis a partir de antigos referenciais. Concluímos que um conhecimento mais aprofundado das transformações radicais em curso no mundo atual pode ajudar os psicólogos a rever suas antigas certezas a respeito do homem e a aventurar novos olhares sobre os também novos fenômenos humanos.Profound changes in the contemporary world have created a new context for scientific work, characterised by the deconstruction of old theories and the construction of a new network of knowledge. In this article, we analyse a few theories recently developed in the social sciences and in philosophy that make up this network: post-modernist theories, reflexive modernisation theories and Information Technology Revolution theory. In this way, we aim to provide psychologists with insights produced in other fields of knowledge that can serve as a starting point for the analysis of the subjective changes introduced by the new global scenario. We argue that psychology still observes contemporary man on the basis of traditional categories, ignoring the fact that profound social changes

The geopolitics in the spheres of influence, domination, and overrule: towards a new world order or disorder?

OpenAIRE

Mulaj, Isa

2012-01-01

The term New World Order (NWO) appears to get a more comprehensive meaning from the most recent evolution of dramatic events in various parts of the world. Officially, there is still no any unified approach how it may look like, upon which pillars it will be built, and how it would operate. More assumptions can be heard by ordinary people than by those who are believed to have considerable impact on the flows of this outspoken order. Unlike great revolutionary changes of the past, e.g. the be...

Understanding Online (Game)worlds

Science.gov (United States)

Klastrup, Lisbeth

With gameworlds as the prime example, this article discusses online worlds as new forms of cultural entertainment systems and presents a framework with which to analyse them. The framework takes its point of departure in a discussion of what online gameworlds are, which genres of worlds exist and how they can be understood as a new form of engaging experience similar to the type of experience we have when we are captivated by the fictional universes of novels, films and tabletop roleplaying games. The proposed framework is grounded in an aesthetic, communicative and sociological approach to online worlds as digital phenomena, with the primary objective of describing how online gameworlds are systems that create meaning through the production of the experience of “worldness”.

China in World Industrialization

NARCIS (Netherlands)

XU, Yi; van Leeuwen, Bas

2016-01-01

Combining the sectoral accounting method of the System of National Accounts (SNA) with new statistical materials from the United Nations, as well as historical research into various countries around the world, this paper arrives at an estimate of value added of Chinese and world industries between

Side impact injury prediction with fe simulations of the new advanced world sid fe dummy models

NARCIS (Netherlands)

Liu, Y.; Zhu, F.; Wang, Z.; Ratingen, M.R. van

2007-01-01

Two new World SID (50th and 5th) FE models were developed for providing virtual tools of predicting occupant injuries during vehicle side collisions. The virtual dummy models have been verified with their physical counterparts in aspects of lab certification tests, bio-fidelity and sled tests. Many

Fundamental characteristics of the immunoglobulin VH repertoire of chickens in comparison with those of humans, mice, and camelids.

Science.gov (United States)

Wu, Leeying; Oficjalska, Katarzyna; Lambert, Matthew; Fennell, Brian J; Darmanin-Sheehan, Alfredo; Ní Shúilleabháin, Deirdre; Autin, Bénédicte; Cummins, Emma; Tchistiakova, Lioudmila; Bloom, Laird; Paulsen, Janet; Gill, Davinder; Cunningham, Orla; Finlay, William J J

2012-01-01

Examination of 1269 unique naive chicken V(H) sequences showed that the majority of positions in the framework (FW) regions were maintained as germline, with high mutation rates observed in the CDRs. Many FW mutations could be clearly related to the modulation of CDR structure or the V(H)-V(L) interface. CDRs 1 and 2 of the V(H) exhibited frequent mutation in solvent-exposed positions, but conservation of common structural residues also found in human CDRs at the same positions. In comparison with humans and mice, the chicken CDR3 repertoire was skewed toward longer sequences, was dominated by small amino acids (G/S/A/C/T), and had higher cysteine (chicken, 9.4%; human, 1.6%; and mouse, 0.25%) but lower tyrosine content (chicken, 9.2%; human, 16.8%; and mouse 26.4%). A strong correlation (R(2) = 0.97) was observed between increasing CDR3 length and higher cysteine content. This suggests that noncanonical disulfides are strongly favored in chickens, potentially increasing CDR stability and complexity in the topology of the combining site. The probable formation of disulfide bonds between CDR3 and CDR1, FW2, or CDR2 was also observed, as described in camelids. All features of the naive repertoire were fully replicated in the target-selected, phage-displayed repertoire. The isolation of a chicken Fab with four noncanonical cysteines in the V(H) that exhibits 64 nM (K(D)) binding affinity for its target proved these constituents to be part of the humoral response, not artifacts. This study supports the hypothesis that disulfide bond-constrained CDR3s are a structural diversification strategy in the restricted germline v-gene repertoire of chickens.

John’s Apocalypse: Dynamic word-images for a new world

Directory of Open Access Journals (Sweden)

Sergio Rosell

2011-04-01

Full Text Available The aim of the article is to investigate the function of the symbols and images in the Apocalypse of John. Its aim is to focus on the ‘mental scenarios’ readers are bringing to the text, rather than on John’s supposed lack of ability to convey his message. The article discusses both the symbolic or iconographic and the evocative power within the historical situation which the author of the Apocalypse addresses. The article’s intention is to show how John reveals an alternative way of understanding history through the use of his particular imagery, aided by film theory tools and based on previous work that had perceived the Apocalypse’s ‘theatrical’ nature, in order to discover John’s use of images, their function and the new world he aims to portray.

Proteomics of old world camelid (Camelus dromedarius: Better understanding the interplay between homeostasis and desert environment

Directory of Open Access Journals (Sweden)

Mohamad Warda

2014-03-01

Full Text Available Life is the interplay between structural–functional integrity of biological systems and the influence of the external environment. To understand this interplay, it is useful to examine an animal model that competes with harsh environment. The dromedary camel is the best model that thrives under severe environment with considerable durability. The current proteomic study on dromedary organs explains a number of cellular mysteries providing functional correlates to arid living. Proteome profiling of camel organs suggests a marked increased expression of various cytoskeleton proteins that promote intracellular trafficking and communication. The comparative overexpression of α-actinin of dromedary heart when compared with rat heart suggests an adaptive peculiarity to sustain hemoconcentration–hemodilution episodes associated with alternative drought-rehydration periods. Moreover, increased expression of the small heat shock protein, α B-crystallin facilitates protein folding and cellular regenerative capacity in dromedary heart. The observed unbalanced expression of different energy related dependent mitochondrial enzymes suggests the possibility of mitochondrial uncoupling in the heart in this species. The evidence of increased expression of H+-ATPase subunit in camel brain guarantees a rapidly usable energy supply. Interestingly, the guanidinoacetate methyltransferase in camel liver has a renovation effect on high energy phosphate with possible concomitant intercession of ion homeostasis. Surprisingly, both hump fat tissue and kidney proteomes share the altered physical distribution of proteins that favor cellular acidosis. Furthermore, the study suggests a vibrant nature for adipose tissue of camel hump by the up-regulation of vimentin in adipocytes, augmenting lipoprotein translocation, blood glucose trapping, and challenging external physical extra-stress. The results obtained provide new evidence of homeostasis in the arid habitat

Endogenous New World primate type C viruses isolated from owl monkey (Aotus trivirgatus) kidney cell line.

Science.gov (United States)

Todaro, G J; Sherr, C J; Sen, A; King, N; Daniel, M D; Fleckenstein, B

1978-01-01

A type C virus (OMC-1) detected in a culture of owl monkey kidney cells resembled typical type C viruses morphologically, but was slightly larger than previously characterized mammalian type C viruses. OMC-1 can be transmitted to bat lung cells and cat embryo fibroblasts. The virions band at a density of 1.16 g/ml in isopycnic sucrose density gradients and contain reverse transcriptase and a 60-65S RNA genome composed of approximately 32S subunits. The reverse transcriptase is immunologically and biochemically distinct from the polymerases of othe retroviruses. Radioimmunoassays directed to the interspecies antigenic determinants of the major structure proteins of other type C viruses do not detect a related antigen in OMC-1. Nucleic acid hybridization experiments using labeled viral genomic RNA or proviral cDNA transcripts to normal cellular DNA of different species show that OMC-1 is an endogenous virus with multiple virogene copies (20-50 per haploid genome) present in normal owl monkey cells and is distinct from previously isolated type C and D viruses. Sequences related to the OMC-1 genome can be detected in other New World monkeys. Thus, similar to the Old World primates (e.g., baboons as a prototype), the New World monkeys contain endogenous type C viral genes that appear to have been transmitted in the primate germ line. Images PMID:76312

Contemporary world migration - towards new terminology, patterns and policies

Directory of Open Access Journals (Sweden)

Šantić Danica

2016-01-01

Full Text Available In the last decades, after the Cold War and the fall of the Berlin wall, the strengthening of overall population mobility is evident on local, regional, national and global scale. In addition, there are changes in the scope and direction of migration, their structural characteristics and increasing in the number of determining factors and consequences, which affects the complexity of this phenomenon. It is important to point out the emergence of new forms of migration as a result of intensifying pace of globalization, which is an integral part of the migration. The total number of migrants in the world (internal and external in the first decade of the XXI century reached the highest value in history and is around one billion, with small, but continuous increase in share of total population. This means that one in every seven person in the world has changed place of residence, either within their own country (about 700 million of internal migrants or moved to another country (244 million international migrants. Therefore some authors points out that all of us are becoming migrants. Also, the number of irregular migrants recently has reached its highest amount, which implies an intensification of government actions to regulate migration through the creation of effective policies, spatial mobility and intensification of bilateral, regional and international negotiations in this domain. Estimates show that the number of migrants will continue to grow, especially the number of climate migrants, persons who left their homes due to changes in the environment. That is why it is of crucial importance in a first place to understand migrations properly and then to create the steps towards the best solutions in solving the problems caused by population movement in space and create proper migration policies.

The New Geographical Structures of the Capitalist World-Economy and the Role of the BRICS: a View from Brazil

Directory of Open Access Journals (Sweden)

Alexandre de Freitas Barbosa

2014-06-01

Full Text Available This paper presents an alternative theoretical framework in order to understand the new nature of the capitalist world-economy and its corresponding international division of labor. It studies the meaning of BRICS by examining the once-held belief that the world was divided by a center, semi-periphery and periphery; it analyses the newly established divisions of intra-South and intra-North. These countries operate under various forms of capitalism, thus creating new power relations that work collectively from a geopolitical standpoint. Despite weak economic ties, with the exception of China, leaders of the BRICS are attempting to promote a reform within multilateral organizations and the G-20. The objective of this paper is to shed light on such challenges to this new strategy facing these countries, particularly from the perspective of Brazil’s foreign policy.

At the threshold to a new world

International Nuclear Information System (INIS)

Boeer, K.W.

1993-01-01

The rapidly declining ecological health of the globe and its contributing factors are reviewed, and a global health index is defined that helps visualizing approaching danger points. The close relationship between ecologically declining health, the need for more energy per capita world-wide and the economic growth as a driving force are discussed. Large scale reforestation to counteract greenhouse gas imbalance is described as temporary aid to buy time and avoid instabilities in weather patterns until more permanent solutions can be in place that permit further economic growth of the total gross world product. The only feasible solution that does not mortgage future generations with yet unsolved, and possibly unsolvable problems is the massive deployment of solar conversion equipment. The use of photovoltaic panels is a well established technology and is described as a totally benign solution that, in conjunction with hydrogen storage, can be used as the dominant future source of energy on earth

Making “World Machines”

DEFF Research Database (Denmark)

Light, Ann; Bardzell, Jeffrey; Bardzell, Shaowen

2015-01-01

be combined and turned to crowd-sourcing public engagement with shared world issues - as an alternative to business-as-usual in the context of developing and deploying networked technology. We combine theoretical aspects of world machines, such as what a political entity of this kind might seek to do......The world machine is a new archetype for a socio-technical system drawing together a group of tools that combine computational powers with a social agenda of cross-world collaboration in resistance to dominant market rhetoric. Specifically, we look at how powers to connect, sense and infer can...

Performance Comparison of Four SolarWorld Module Technologies at the US DOE Regional Test Center in New Mexico: November 2016 - March 2017.

Energy Technology Data Exchange (ETDEWEB)

Burnham, Laurie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lave, Matthew Samuel [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Stein, Joshua [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-07-01

This report provides a preliminary (three month) analysis for the SolarWorld system installed at the New Mexico Regional Test Center (RTC.) The 8.7kW, four-string system consists of four module types): bifacial, mono-crystalline, mono-crystalline glass-glass and polycrystalline. Overall, the SolarWorld system has performed well to date: most strings closely match their specification-sheet module temperature coefficients and Sandia 's f lash tests show that Pmax values are well within expectations. Although the polycrystalline modules underperformed, the results may be a function of light exposure, as well as mismatch within the string, and not a production flaw. The instantaneous bifacial gains for SolarWorld 's Bisun modules were modest but it should be noted that the RTC racking is not optimized for bifacial modules, nor is albedo optimized at the site. Additional analysis, not only of the SolarWorld installation in New Mexico but of the SolarWorld installations at the Vermont and Florida RTCs will be provide much more information regarding the comparative performance of the four module types.

World Energy Prospects and Stakes. A New Paradigm

International Nuclear Information System (INIS)

Laponche, Bernard; DEVERNOIS, Nils

2008-01-01

To pursue the present path in the development of energy systems would lead to growing insecurity of supply and an unacceptable increase in greenhouse gas emissions. Both climate change (and other environmental hazards) and security of supply would rapidly become formidable obstacles for peace and development if energy consumption follows such an 'impossible path'. Energy security and environmental constraints converge to offer mankind both a challenge and opportunity: to invent a new model compatible with sustainable development, in order to 'meet the needs of the present without compromising the ability of future generations to meet their own needs'. Energy efficiency comes first, because it presents the largest potential, it is applicable to all sectors of activities in all countries and because it is a pre-requisite to slow down the depletion rate of fossil fuel resources and to ensure a rational and significant increase of the share of renewable energy sources in total energy requirements. An energy efficiency strategy is not a slight adjustment to an energy supply policy but a new concept of economic policy which takes into account the costs of environmental degradation, growing energy insecurity and the medium and long term trend of increasing energy costs. Industrialised countries can and must reduce their total energy consumption. Most developing countries must increase their energy consumption for their economic development, but they can reach this objective with much lower growth than industrialised countries in the past by applying energy efficiency strategies. At world level, priority should be given to energy efficiency in the Transport sector, literally tied to oil products, and to electricity consumption in the household and service sectors since electricity production is a voracious and expensive consumer of natural resources. (author)

World Energy Prospects and Stakes. A New Paradigm

International Nuclear Information System (INIS)

Laponche, B.

2008-01-01

To pursue the present path in the development of energy systems would lead to growing insecurity of supply and an unacceptable increase in greenhouse gas emissions. Both climate change (and other environmental hazards) and security of supply would rapidly become formidable obstacles for peace and development if energy consumption follows such an 'impossible path'. Energy security and environmental constraints converge to offer mankind both a challenge and opportunity: to invent a new model compatible with sustainable development, in order to 'meet the needs of the present without compromising the ability of future generations to meet their own needs'. Energy efficiency comes first, because it presents the largest potential, it is applicable to all sectors of activities in all countries and because it is a pre-requisite to slow down the depletion rate of fossil fuel resources and to ensure a rational and significant increase of the share of renewable energy sources in total energy requirements. An energy efficiency strategy is not a slight adjustment to an energy supply policy but a new concept of economic policy which takes into account the costs of environmental degradation, growing energy insecurity and the medium and long term trend of increasing energy costs. Industrialized countries can and must reduce their total energy consumption. Most developing countries must increase their energy consumption for their economic development, but they can reach this objective with much lower growth than industrialized countries in the past by applying energy efficiency strategies. At world level, priority should be given to energy efficiency in the Transport sector, literally tied to oil products, and to electricity consumption in the household and service sectors since electricity production is a voracious and expensive consumer of natural resources. (authors)

A new world malaria map: Plasmodium falciparum endemicity in 2010.

Science.gov (United States)

Gething, Peter W; Patil, Anand P; Smith, David L; Guerra, Carlos A; Elyazar, Iqbal R F; Johnston, Geoffrey L; Tatem, Andrew J; Hay, Simon I

2011-12-20

Transmission intensity affects almost all aspects of malaria epidemiology and the impact of malaria on human populations. Maps of transmission intensity are necessary to identify populations at different levels of risk and to evaluate objectively options for disease control. To remain relevant operationally, such maps must be updated frequently. Following the first global effort to map Plasmodium falciparum malaria endemicity in 2007, this paper describes the generation of a new world map for the year 2010. This analysis is extended to provide the first global estimates of two other metrics of transmission intensity for P. falciparum that underpin contemporary questions in malaria control: the entomological inoculation rate (PfEIR) and the basic reproductive number (PfR). Annual parasite incidence data for 13,449 administrative units in 43 endemic countries were sourced to define the spatial limits of P. falciparum transmission in 2010 and 22,212 P. falciparum parasite rate (PfPR) surveys were used in a model-based geostatistical (MBG) prediction to create a continuous contemporary surface of malaria endemicity within these limits. A suite of transmission models were developed that link PfPR to PfEIR and PfR and these were fitted to field data. These models were combined with the PfPR map to create new global predictions of PfEIR and PfR. All output maps included measured uncertainty. An estimated 1.13 and 1.44 billion people worldwide were at risk of unstable and stable P. falciparum malaria, respectively. The majority of the endemic world was predicted with a median PfEIR of less than one and a median PfRc of less than two. Values of either metric exceeding 10 were almost exclusive to Africa. The uncertainty described in both PfEIR and PfR was substantial in regions of intense transmission. The year 2010 has a particular significance as an evaluation milestone for malaria global health policy. The maps presented here contribute to a rational basis for control and

A new world malaria map: Plasmodium falciparum endemicity in 2010

Directory of Open Access Journals (Sweden)

Gething Peter W

2011-12-01

Full Text Available Abstract Background Transmission intensity affects almost all aspects of malaria epidemiology and the impact of malaria on human populations. Maps of transmission intensity are necessary to identify populations at different levels of risk and to evaluate objectively options for disease control. To remain relevant operationally, such maps must be updated frequently. Following the first global effort to map Plasmodium falciparum malaria endemicity in 2007, this paper describes the generation of a new world map for the year 2010. This analysis is extended to provide the first global estimates of two other metrics of transmission intensity for P. falciparum that underpin contemporary questions in malaria control: the entomological inoculation rate (PfEIR and the basic reproductive number (PfR. Methods Annual parasite incidence data for 13,449 administrative units in 43 endemic countries were sourced to define the spatial limits of P. falciparum transmission in 2010 and 22,212 P. falciparum parasite rate (PfPR surveys were used in a model-based geostatistical (MBG prediction to create a continuous contemporary surface of malaria endemicity within these limits. A suite of transmission models were developed that link PfPR to PfEIR and PfR and these were fitted to field data. These models were combined with the PfPR map to create new global predictions of PfEIR and PfR. All output maps included measured uncertainty. Results An estimated 1.13 and 1.44 billion people worldwide were at risk of unstable and stable P. falciparum malaria, respectively. The majority of the endemic world was predicted with a median PfEIR of less than one and a median PfRc of less than two. Values of either metric exceeding 10 were almost exclusive to Africa. The uncertainty described in both PfEIR and PfR was substantial in regions of intense transmission. Conclusions The year 2010 has a particular significance as an evaluation milestone for malaria global health policy. The

Wiki management a revolutionary new model for a rapidly changing and collaborative world

CERN Document Server

Collins, Rod

2013-01-01

We now live in a "wiki" world where mass collaboration is not only possible-it's often the best solution. Conventional management thought assumes that command-and-control is the most effective way to organize the efforts of large numbers of people, but rapid change and increasing complexity have rendered that model obsolete. As a result, most managers today lack the skills and knowledge needed to succeed in an age when networks are proving smarter and faster than hierarchies. Designing organizations for mass collaboration demands a new and very different model-wiki management.

Genomic characterization of H14 subtype Influenza A viruses in new world waterfowl and experimental infectivity in mallards (Anas platyrhynchos.

Directory of Open Access Journals (Sweden)

Andrew M Ramey

Full Text Available Recent repeated isolation of H14 hemagglutinin subtype influenza A viruses (IAVs in the New World waterfowl provides evidence to suggest that host and/or geographic ranges for viruses of this subtype may be expanding. In this study, we used genomic analyses to gain inference on the origin and evolution of H14 viruses in New World waterfowl and conducted an experimental challenge study in mallards (Anas platyrhynchos to evaluate pathogenicity, viral replication, and transmissibility of a representative viral strain in a natural host species. Genomic characterization of H14 subtype IAVs isolated from New World waterfowl, including three isolates sequenced specifically for this study, revealed high nucleotide identity among individual gene segments (e.g. ≥95% shared identity among H14 HA gene segments. In contrast, lower shared identity was observed among internal gene segments. Furthermore, multiple neuraminidase subtypes were observed for H14 IAVs isolated in the New World. Gene segments of H14 viruses isolated after 2010 shared ancestral genetic lineages with IAVs isolated from wild birds throughout North America. Thus, genomic characterization provided evidence for viral evolution in New World waterfowl through genetic drift and genetic shift since purported introduction from Eurasia. In the challenge study, no clinical disease or lesions were observed among mallards experimentally inoculated with A/blue-winged teal/Texas/AI13-1028/2013(H14N5 or exposed via contact with infected birds. Titers of viral shedding for mallards challenged with the H14N5 IAV were highest at two days post-inoculation (DPI; however shedding was detected up to nine DPI using cloacal swabs. The distribution of viral antigen among mallards infected with H14N5 IAV was largely restricted to enterocytes lining the villi in the lower intestinal tract and in the epithelium of the bursa of Fabricius. Characterization of the infectivity of A/blue-winged teal/Texas/AI13

American religion: diaspora and syncretism from Old World to New

Directory of Open Access Journals (Sweden)

Aisha Khan

2003-01-01

Full Text Available [First paragraph] Nation Dance: Religion, Identity, and Cultural Difference in the Caribbean. PATRICK TAYLOR (ed.. Bloomington: Indiana University Press, 2001. x +220 pp. (Paper US$ 19.95 Translating Kali 's Feast: The Goddess in Indo-Caribbean Ritual and Fiction. STEPHANOS STEPHANIDES with KARNA SINGH. Amsterdam: Rodopi, 2000. xii + 200 pp. (Paper US$ 19.00 Between Babel and Pentecost: Transnational Pentecostalism in Africa and Latin America. ANDRÉ CORTEN & RUTH MARSHALL-FRATANI (eds.. Bloomington: Indiana University Press, 2001. 270 pp. (Paper US$ 22.95 Encyclopedia of African and African-American Religions. STEPHEN D. GLAZIER (ed.. New York: Routledge, 2001. xx + 452 pp. (Cloth US$ 125.00 As paradigms and perspectives change within and across academie disciplines, certain motifs remain at the crux of our inquiries. Evident in these four new works on African and New World African and South Asian religions are two motifs that have long defined the Caribbean: the relationship between cultural transformation and cultural continuity, and that between cultural diversity and cultural commonality. In approaching religion from such revisionist sites as poststructuralism, diaspora, hybridity, and creolization, however, the works reviewed here attempt to move toward new and more productive ways of thinking about cultures and histories in the Americas. In the process, other questions arise. Particularly, can what are essentially redirected language and methodologies in the spirit of postmodern interventions teil us more about local interpretation, experience, and agency among Caribbean, African American, and African peoples than can more traditional approaches? While it is up to individual readers to decide this for themselves, my own feeling is that it is altogether a good thing that these works still echo long-standing conundrums: the Herskovits/Frazier debate over cultural origins, the tensions of assimilation in "plural societies," and the

Clashing world views

International Nuclear Information System (INIS)

Lagassa, G.

1992-01-01

This article examines how politics, economics, and an increasing awareness of environmental and societal impacts are affecting the market for new hydroelectric projects. The topics of the article include border conflicts, new opposition, resettlement issues, the problems and benefits of hydroelectric projects, taking action, and a clash of world views

The Shifting Global Power Balance Equations and the Emerging Real ‘New World Order’

OpenAIRE

Ovie-D’Leone, Alex Igho

2010-01-01

Expansion in globalization arising from increased interconnectivity and interdependence across the worldis causing a shift both in the focus of what now could determine the principal international powervariables and the criteria for power balancing calculus. One direct challenge to the status quo is theemergence on one hand of new state actors which are becoming more assertive, as well as some other newkey non-state actors now matching states seemingly one-on-one on the world stage in many sp...

75 FR 35951 - World Refugee Day, 2010

Science.gov (United States)

2010-06-23

... humanitarian aid, America's leadership in international relief efforts and in defense of human rights has... the world's most vulnerable individuals, enriching our own country and advancing our leadership in the world. Refugees face daunting challenges in an unfamiliar society with new rules, new resources, and...

Major changes in the world's nuclear power at the beginning of the new century

International Nuclear Information System (INIS)

Dumitrache, Ion

2002-01-01

In the last decade of the 20th century the world nuclear power recorded some characteristic trends among which one can mention the following: - Almost total absence of investments in new NPPs in the industrialized countries except Japan and South Korea; - Policy of some governments to decrease the nuclear power sector in their countries up to a complete stop of electricity production in a foreseeable future (as in case of Sweden, Germany, Nederland and Belgium); - Projections indicating a steady decline of nuclear share in the national power production as for instance in USA, Germany, Great Britain, and other industrialized countries; - pressures upon countries late owners of soviet type NPPs in order to shut down completely the RBMK and WWER reactors; - a drastic reduction of the funds afforded for research dedicated to fission reactors of new concept, except Japan and South Korea; - almost negligible effects of the Kyoto protocol upon nuclear power, hopes being directed towards renewable energy sources. After second half of the year 1998 modest signals of future changes in the energy policy occurred. The US government admitted on basis of performance assessments and projections that the important role of nuclear power in US will be extended still for long after the years 2020-2030. Consequently, research concerning the future demand for fission based power began be financed. Gradually the countries of EU and Canada modified also their official position towards the role of nuclear fission in ensuring the electric energy needs of the future. The beginning of the new century was marked by a significant acceleration of changes of opinions in favor of nuclear power. Japan and South Korea stated that at least in the first half of the 21th century the fission NPP's will play a major role. Russia promoted new WWER reactor types of safety standards equivalent or higher than the western ones. Also China and India launched ambitious plans for building new NPPs. These new

New markets in the new world

International Nuclear Information System (INIS)

Robinson, T.

1991-01-01

Two important shifts occurred during the early 1990s that have enhanced the long-term market opportunities for natural gas, notes the author of this paper. First, as a result of the Gulf Crisis, there was renewed concern about energy security, reinforcing the position of natural gas as an attractive alterative fuel to oil. Second, the perhaps more significant, there was the sudden realization by many in the industry that the gas supply was not rapidly declining and that with expanding imports, severe competition may lie ahead if new markets were not developed. These changes have broken the rules about gas price parity with oil and may lead to greater flexibility toward and interest in long-term contracts. Many of the new markets that are being pursued focus on the opportunities arising from the energy security/environmental agenda, including fuel switching in the residential and utility sectors; the development of compressed natural gas (CNG) vehicles; and opportunities for gas arising from the Clean Air Act of 1990

World Energy Future

International Nuclear Information System (INIS)

Forbes, A.; Van der Linde, C.; Nicola, S.

2009-01-01

In the section World Energy Future of this magazine two articles, two interviews and one column are presented. The article 'A green example to the world' refers briefly to the second World Future Energy Summit in Abu Dhabi, which was held from 18-21 January, 2009. The second article, 'Green Utopia in the desert' attention is paid to the Abu Dhabi government-driven Masdar Initiative. The two interviews concern an interview with BP Alternative Energy ceo Vivienne Cox, and an interview with the founder and CEO of New Energy Finance Michael Liebreich. The column ('An efficient response') focuses on the impact of the economic crisis on energy policy

Bridging scales of crustal stress patterns using the new World Stress Map

Science.gov (United States)

Heidbach, O.; Rajabi, M.; Cui, X.; Fuchs, K. W.; Mueller, B.; Reinecker, J.; Reiter, K.; Tingay, M. R. P.; Wenzel, F.; Xie, F.; Ziegler, M.; Zoback, M. D.; Zoback, M. L.

2017-12-01

Knowledge of the contemporary crustal stress field is a key parameter for the understanding of geodynamic processes such as global plate tectonics and the earthquake cycle. It is also an essential parameter for our sustainable and safe usage of Earth's resources, which is a major challenge for energy security in the 21st century. Since 1986, the World Stress Map (WSM) project has systematically compiled present-day stress information and provides a unique public domain global database. It is a long-term project based on an international network of partners from academia and industry. All data are public and available on the project website at world-stress-map.org. For the 30th anniversary of the project a new database has been compiled, containing double the amount of data records (n=42,870) including new data records from almost 4,000 deep boreholes. The new compilation focused on areas with previously sparse data coverage in order to resolve the stress pattern on different spatial scales. The significantly higher data density can now be used to resolve stress pattern heterogeneities on regional and local scales, as well as with depth in some regions. We present three results derived from the new WSM compilation: 1.) The global comparison between absolute plate motion and the mean of the orientation of maximum horizontal stress SHmax on a regular grid shows that there is still a correlation for the North and South America plate, but deviations from this general trend are now also clearly resolved. 2.) The variability of the crustal stress pattern changes when zooming in from plate-wide scale down to basin scale at 100 km. We show examples for Eastern Australia, Oklahoma and Central Europe. This regional and local variability of the stress pattern can be used as a proxy to identify and quantify regional and local stress sources by means of geomechanical-numerical models of the 3D stress tensor. 3.) Finally we present briefly the general concept of a multi-stage 3D

Galaxy Collisions Forging New Worlds from Cosmic Crashes

CERN Document Server

Struck, Curtis

2011-01-01

Galaxy collisions are the key process in building galaxies, triggering the formation of stars and the build-up of heavy elements that allow the formation of planets and solar systems. This book presents the revolutionary research advances achieved in the last decade and lucidly explains the underlying dynamical processes. Galaxy Collisions takes a comprehensive trip through the visually spectacular world of galaxy collisions; investigates the interactions of stars, gas clouds, and dark matter in galaxy collisions; uses analogies and metaphors to help comprehend the bizarre world of galaxies; presents recent research results to enhance the understanding of galaxy formation and evolution; includes discoveries of minor collisions within our own group of galaxies; shows how a galaxy collision might affect a solar system, or a planet like ours.

YottaYotta announces new world record set for TCP disk-to-disk bulk transfer

CERN Document Server

2002-01-01

The Yottabyte NetStorage(TM) Company, today announced a new world record for TCP disk-to-disk data transfer using the company's NetStorager(R) System. The record-breaking demonstration transferred 5 terabytes of data between Chicago, Il. to Vancouver, BC and Ottawa, ON, at a sustained average throughput of 11.1 gigabits per second. Peak throughput exceeded 11.6 gigabits per second, more than 15-times faster than previous records for TCP transfer from disk-to-disk (1 page).

Persistence of the mitochondrial lineage responsible for the Irish potato famine in extant New World Phytophthora infestans

DEFF Research Database (Denmark)

Martin, Michael David; Ho, Simon Y W; Wales, Nathan

2014-01-01

)-century Europe, three from 1950s U.K. and 34 from modern populations across the New World. We use phylogenetic analyses to identify the HERB-1 lineage in modern populations from both Mexico and South America, and to demonstrate distinct mitochondrial haplotypes were present in 19(th)-century Europe...

WorldWide Telescope and Google Sky: New Technologies to Engage Students and the Public

Science.gov (United States)

Landsberg, R. H.; Subbarao, M. U.; Dettloff, L.

2010-08-01

New, visually rich, astronomical software environments coupled with large web-accessible data sets hold the promise of new and exciting ways to teach, collaborate, and explore the universe. These freeware tools provide contextual views of astronomical objects, real time access to multi-wavelength sky surveys, and, most importantly, the ability to incorporate new data and to produce user created content. This interactive panel examined the capabilities of Google Sky and WorldWide Telescope, and explored case studies of how these tools have been used to create compelling and participatory educational experiences in both formal (i.e., K-12 and undergraduate non-science majors classrooms), and informal (e.g., museum) settings. The overall goal of this session was to stimulate a discussion about future uses of these technologies. Substantial time was allotted for participants to create conceptual designs of learning experiences for use at their home institutions, with feedback provided by the panel members. Activities included technical discussions (e.g., mechanisms for incorporating new data and dissemination tools), exercises in narrative preparation, and a brainstorming session to identify potential future uses of these technologies.

Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains

DEFF Research Database (Denmark)

Álvarez-Cienfuegos, Ana; Alanes, Natalia Nuñez del Prado; Compte, Marta

2016-01-01

Here, we describe a new strategy that allows the rapid and efficient engineering of mono and multispecific trivalent antibodies. By fusing single-domain antibodies from camelid heavy-chain-only immunoglobulins (VHHs) to the N-terminus of a human collagen XVIII trimerization domain (TIEXVIII) we p...

The prion protein and New World primate phylogeny

Directory of Open Access Journals (Sweden)

Igor Schneider

2004-01-01

Full Text Available The PrP C prion protein contains 250 amino acids with some variation among species and is expressed in several cell types. PrP C is converted to PrP Sc by a post-translational process in which it acquires amino acid sequences of three-dimensional conformation of beta-sheets. Variations in the prion protein gene were observed among 16 genera of New World primates (Platyrrhini, and resulted in amino acid substitutions when compared with the human sequence. Seven substitutions not yet described in the literature were found: W -> R at position 31 in Cebuella, T -> A at position 95 in Cacajao and Chiropotes, N-> S at position 100 in Brachyteles, L -> Q at position 130 in Leontopithecus (in the sequence responsible for generating the beta-sheet 1, D -> E at position 144 in Lagothrix (in the sequence responsible for the alpha-helix 1, D-> G at position 147 in Saguinus (also located in the alpha-helix 1 region, and M -> I at position 232 in Alouatta. The phylogenetic trees generated by parsimony, neighbor-joining and Bayesian analyses strongly support the monophyletic status of the platyrrhines, but did not resolve relationships among families. However, the results do corroborate previous findings, which indicate that the three platyrrhine families radiated rapidly from an ancient split.

A New World for Museum Marketing? Facing the Old Dilemmas while Challenging New Market Opportunities

Directory of Open Access Journals (Sweden)

Tanja Komarac

2014-12-01

Full Text Available Museums are part of a wider cultural and entertainment environment, which is ruled by highly demanding visitors who seek immersive experiences (edutainment and time-saving arrangement. This has encouraged and, in some opinions, forced museums to turn their focus from collections to visitors. In addition, museums have faced competition and new technologies in the form of virtual museums and virtual reality. This has emphasized the need to accept marketing as a survival tool and to make it into a link between museums and visitors. This article attempts to give current insights into museum marketing as part of the arts marketing field. Its aim is also to identify and explain some of the major challenges and opportunities facing everyday museum business, in order to provide insight into the complex world of museum marketing. Former findings about the development of museum marketing and its biggest changes and challenges are presented, summarized and analyzed.

World Energy Future

Energy Technology Data Exchange (ETDEWEB)

Forbes, A.; Van der Linde, C.; Nicola, S.

2009-03-15

In the section World Energy Future of this magazine two articles, two interviews and one column are presented. The article 'A green example to the world' refers briefly to the second World Future Energy Summit in Abu Dhabi, which was held from 18-21 January, 2009. The second article, 'Green Utopia in the desert' attention is paid to the Abu Dhabi government-driven Masdar Initiative. The two interviews concern an interview with BP Alternative Energy ceo Vivienne Cox, and an interview with the founder and CEO of New Energy Finance Michael Liebreich. The column ('An efficient response') focuses on the impact of the economic crisis on energy policy.

Development and Characterization of a Camelid Single Domain Antibody-Urease Conjugate That Targets Vascular Endothelial Growth Factor Receptor 2.

Science.gov (United States)

Tian, Baomin; Wong, Wah Yau; Uger, Marni D; Wisniewski, Pawel; Chao, Heman

2017-01-01

Angiogenesis is the process of new blood vessel formation and is essential for a tumor to grow beyond a certain size. Tumors secrete the pro-angiogenic factor vascular endothelial growth factor, which acts upon local endothelial cells by binding to vascular endothelial growth factor receptors (VEGFRs). In this study, we describe the development and characterization of V21-DOS47, an immunoconjugate that targets VEGFR2. V21-DOS47 is composed of a camelid single domain anti-VEGFR2 antibody (V21) and the enzyme urease. The conjugate specifically binds to VEGFR2 and urease converts endogenous urea into ammonia, which is toxic to tumor cells. Previously, we developed a similar antibody-urease conjugate, L-DOS47, which is currently in clinical trials for non-small cell lung cancer. Although V21-DOS47 was designed from parameters learned from the generation of L-DOS47, additional optimization was required to produce V21-DOS47. In this study, we describe the expression and purification of two versions of the V21 antibody: V21H1 and V21H4. Each was conjugated to urease using a different chemical cross-linker. The conjugates were characterized by a panel of analytical techniques, including SDS-PAGE, size exclusion chromatography, Western blotting, and LC-MS E peptide mapping. Binding characteristics were determined by ELISA and flow cytometry assays. To improve the stability of the conjugates at physiologic pH, the pIs of the V21 antibodies were adjusted by adding several amino acid residues to the C-terminus. For V21H4, a terminal cysteine was also added for use in the conjugation chemistry. The modified V21 antibodies were expressed in the E. coli BL21 (DE3) pT7 system. V21H1 was conjugated to urease using the heterobifunctional cross-linker succinimidyl-[( N -maleimidopropionamido)-diethyleneglycol] ester (SM(PEG) 2 ), which targets lysine resides in the antibody. V21H4 was conjugated to urease using the homobifunctional cross-linker, 1,8-bis(maleimido)diethylene glycol

Development and Characterization of a Camelid Single Domain Antibody–Urease Conjugate That Targets Vascular Endothelial Growth Factor Receptor 2

Directory of Open Access Journals (Sweden)

Baomin Tian

2017-08-01

Full Text Available Angiogenesis is the process of new blood vessel formation and is essential for a tumor to grow beyond a certain size. Tumors secrete the pro-angiogenic factor vascular endothelial growth factor, which acts upon local endothelial cells by binding to vascular endothelial growth factor receptors (VEGFRs. In this study, we describe the development and characterization of V21-DOS47, an immunoconjugate that targets VEGFR2. V21-DOS47 is composed of a camelid single domain anti-VEGFR2 antibody (V21 and the enzyme urease. The conjugate specifically binds to VEGFR2 and urease converts endogenous urea into ammonia, which is toxic to tumor cells. Previously, we developed a similar antibody–urease conjugate, L-DOS47, which is currently in clinical trials for non-small cell lung cancer. Although V21-DOS47 was designed from parameters learned from the generation of L-DOS47, additional optimization was required to produce V21-DOS47. In this study, we describe the expression and purification of two versions of the V21 antibody: V21H1 and V21H4. Each was conjugated to urease using a different chemical cross-linker. The conjugates were characterized by a panel of analytical techniques, including SDS-PAGE, size exclusion chromatography, Western blotting, and LC-MSE peptide mapping. Binding characteristics were determined by ELISA and flow cytometry assays. To improve the stability of the conjugates at physiologic pH, the pIs of the V21 antibodies were adjusted by adding several amino acid residues to the C-terminus. For V21H4, a terminal cysteine was also added for use in the conjugation chemistry. The modified V21 antibodies were expressed in the E. coli BL21 (DE3 pT7 system. V21H1 was conjugated to urease using the heterobifunctional cross-linker succinimidyl-[(N-maleimidopropionamido-diethyleneglycol] ester (SM(PEG2, which targets lysine resides in the antibody. V21H4 was conjugated to urease using the homobifunctional cross-linker, 1,8-bis

Hepatic lipidosis in llamas and alpacas: 31 cases (1991-1997).

Science.gov (United States)

Tornquist, S J; Van Saun, R J; Smith, B B; Cebra, C K; Snyder, S P

1999-05-01

To identify factors associated with hepatic lipidosis (HL) in llamas and alpacas. Retrospective case series. 30 llamas and 1 alpaca. Medical records were searched to identify llamas or alpacas in which a histologic diagnosis of HL was made. Information was retrieved on signalment, history, clinical and laboratory findings, and results of necropsy or examination of biopsy specimens. Data were analyzed using descriptive statistics and chi 2 analyses. Females were affected more often than males; however, the sex distribution was not different from that of the camelid population in the diagnostic laboratory's database. Fifty-four percent of the females were pregnant, and 46% were lactating. Most affected camelids were 6 to 10 years old. Anorexia and recent weight loss were common (51.6% of camelids). An infective agent was found in only one ilama, and toxins and mineral deficiencies were not identified. The most common abnormalities on serum biochemical analysis were a high concentration of bile acids, high activities of gamma-glutamyltransferase (GGT) and aspartate aminotransferase (AST), and hypoproteinemia. Concentrations of nonesterified fatty acids (NEFA) and beta-hydroxybutyrate (beta-HB) were high in those camelids in which these compounds were assayed. Twenty-nine camelids did not survive. Sick camelids should be considered at risk for developing HL, especially those with anorexia or the metabolic demands of pregnancy and lactation. Other stresses also appear to contribute. High concentrations of NEFA, beta-HB, and bile acids; high activities of GGT and AST; and hypoproteinemia may indicate that HL has developed.

Virtual Worlds: A New Opportunity for People with Lifelong Disability?

Science.gov (United States)

Stendal, Karen; Balandin, Susan; Molka-Danielsen, Judith

2011-01-01

Virtual worlds, such as Second Life[R], are the latest star in the online communication sky. Created by Linden Lab, Second Life is a three-dimensional environment that provides a context for avatars to communicate and socialise with other avatars in a variety of settings (Bell, 2009). Virtual worlds have been used to train people with intellectual…

Prevalence of Mycoplasma haemolamae infection in Peruvian and Chilean llamas and alpacas.

Science.gov (United States)

Tornquist, Susan J; Boeder, Lisa; Rios-Phillips, Carolina; Alarcon, Virgilio

2010-09-01

Mycoplasma haemolamae is a hemotropic mycoplasma that affects red blood cells of llamas (Lama glama) and alpacas (Lama pacos). It is variably associated with anemia, and most infections are subclinical. Development of a polymerase chain reaction assay has facilitated detection of this infection in llamas and alpacas in the United States and other countries. Whether the infection occurs in camelids in South America has previously been unknown. The current study documents a 15.8% infection rate among 76 Peruvian llamas, a 19.3% infection rate among Peruvian alpacas at one site, and a 9.26% infection rate in 108 Chilean alpacas from selected herds. All of the camelids tested appeared to be clinically healthy. No gender or species predilection was found. Only 1 positive camelid younger than 18 months was found. Infection is not associated with anemia, and the mean packed cell volume (PCV) in positive Peruvian camelids was slightly higher than the mean PCV in negative Peruvian camelids. In the Chilean alpacas, the positive alpacas had a slightly lower PCV than the negative alpacas, although the mean PCV was not in the anemic range in any of the groups.

World LNG outlook

International Nuclear Information System (INIS)

Maisonnier, G.

1999-01-01

CEDIGAZ proposes this new survey about LNG in view of the main changes which have occurred on this market during the past few years. Several projects under construction or planned three years ago are now commissioned (Qatargas) or on the verge of starting to export this year (Trinidad LNG, RasGas, Nigeria LNG) or next years (Oman LNG). The Asian crisis, which had major impacts on both short-term demand in Asia and LNG prices, has brought about new uncertainties to the long-term prospects. At the same time, it now seems more and more certain that firstly India and then China will import LNG in the next decade. It remains to be seen at what level and when this will occur. LNG growth in Europe has now become a reality, and new potential markets, for example in South America (Brazil), are also being considered as real opportunities in the near future. Considering these 'new' trends, an updated study about LNG appeared necessary. This survey 'World LNG Outlook - 99 Edition' is organised as the previous one: a historical record since 1964 (Chapter 1) followed by a description of the infrastructures existing in 1998 (Chapter 2). The analysis continues with world trade prospects by the year 2010 (Chapters 3 to 5). Chapter 6 describes the future LNG chain and the last Chapter (7) focuses on economic matters (LNG price trends, cost reductions). The study 'World LNG Outlook - 99 Edition' offers hence a comprehensive panorama of this sector from a short and long-term point of view. (author)

Eschewing New World Order Tensions: Interpretations and Metaphors for Colombian Health System

Directory of Open Access Journals (Sweden)

Juan Carlos Aceros Gualdrón

2003-11-01

Full Text Available This article exemplifies a kind of tension that has been caused by the emergent world order; specifically, the one that has been established between the economic and social rationalities. In order to do so, it portrays the description that the ?Asociación Nacional Pro-Referendo Ley 100? (ANPR made of the Colombia?s Health System in an article called: ?Documento Parcial Preparatorio?. From this article we can highlight some metaphores that exemplify the before metioned tension, the actors involve in it and the proposed political action. In addition to that, there is a use of the cyborg image (Haraway,1991, the idea of the symbiotic contract (Serres, 1990, and the concept of the organizational government (Schvarstein, 2003 to translate the ANPR`s discourse and seek new ways of thinking. This article should not be taken as a reflection of the Health System?s reality. Instead, it should be taken as a possible reading to be given a second thought in order to produce a broader vision of the situation and a new point of view.

Prof. dr. Vesna Vucinic Neškovic - A New President of the World Council of Anthropological Association (WCAA

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Danijela Velimirović

2016-02-01

Full Text Available Vesna Vučinić Nešković PhD, professor at Department of Ethnology and Anthropology,Faculty of Philosophy, University of Belgrade, became in the year 2014 a new President of the World Council of Anthropological Association (WCAA

New possibilities for a secure and just world

Energy Technology Data Exchange (ETDEWEB)

Zagotta, W.E. [ed.

1994-02-28

More than a decade ago individuals from three significant institutions in East Bay Area began discussions in response to the apprehensions that were so deep in the early 1980s. These apprehensions were a result of the intense rhetoric between the two superpowers and the casual commentary about ``limited nuclear war.`` The discussions spoke to the mortal danger as well as to the profound moral question revolving around nuclear arms. The issuance of the US Bishops` Pastoral on War and Peace in 1983 gave the group focus and momentum. The Chancellor at the University of California at Berkeley, the President of the Graduate Theological Union (the consortium of theological schools in Berkeley), and the Director of the Lawrence Livermore National Laboratory (one of the chief designers of American nuclear arms) encouraged us to complete plans for a symposium. It was an era of activism. We chose, however, to serve the theme expressed by Albert Einstein, ``Peace cannot be kept by force, it can only be achieved by understanding.`` After a decade, all of us can commend the leadership of the three institutions and the individuals involved for their perseverance. Their commitments to the pursuit of peace and to the development of an approach to manage the weapons of our time remain a concern of this group even though the great anxiety of a decade ago has subsided. We are now in a time different from that in which the Bishops` Pastoral was written. The talks of Fr. J. Bryan Hehir, Dr. Michael M. May, and Prof. Robert N. Bellah move into new areas of exploration; thus, our theme for this colloquium is ``New Possibilities for a Secure and Just World.`` During our early encounters, one member of our founding group stated that: ``This project will be a work of thirty years.`` Such a profound change in attitude may well be the work of an entire generation.

The Innovation Paradigm of New Industrialization in the Conditions of the Integrated World Economic Way

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Olga Aleksandrovna Romanova

2017-03-01

Full Text Available The article emphasizes the importance of the concept of «technical and economic paradigm», which characterizes the certain stage of the world economy development associated with the corresponding technological revolution. The paper reveals the feature of the modern technical and economic paradigm development connected with new concepts determining a priority of general values. The author states the hypothesis that in the conditions of the emergence of the fourth industrial revolution elements (so-called 4.0 industry, it is fair to consider the innovation paradigm of development as the foundation of the new industrialization which preceds this revolution. The author considers new industrialization as the process contributing to the global technological parity of Russia and the countries-technological leaders. The most significant statements from this post of view are allocated: consideration of new industrialization as a process of continuous innovations and distribution of breakthrough technologies, computerization of production, robotization, cross-disciplinary nature of high technologies, the ecology of technologies, intellectualization of the potential of all persons occupied in industrial production, etc. The author analyses strategic documents connected with the development of innovative activities in Russia. The paper emphasizes that the indicators characterizing these activities do not allow to rank Russia as a country having the developed innovative economy. The article reveals the possibilities of the activation of innovative activities in Russia connected to the development of the approved private priorities in the main spheres of activity with the state priorities of social development; with construction of integrated strategy of a scientific and technological, institutional and industrial development of the country; with creation of the system of scientific monitoring allowing to adjust the necessary corrective actions in time. The

A brave new world: considering the pedagogic potential of Virtual World Field Trips (VWFTs in initial teacher education

Directory of Open Access Journals (Sweden)

Fitzsimons Sabrina

2016-07-01

Full Text Available In its broadest and historical sense, place-based education refers to education that occurs outside of the physical boundaries of a school building (Dewey 1910; Sobel 1996; Theobald 1997; Woodhouse and Knapp 2000. Place-based education, colloquially referred to as the ‘field trip’, is predominantly considered a pedagogic tool of the sciences. It involves a physical movement from the school-based location to a place of interest, for example, a geography field trip to an ecological landscape or science visit to a local museum. This paper considers the use of virtual world field trips (VWFTs within the context of a pre-service Teacher Education programme. The paper presents data from one undergraduate module offered on a programme of initial teacher education. The paper identifies three significant elements of virtual world field trips: place, people and content. First, the virtual world can provide access to places not possible in the offline context as a result of geographic, economic or religious factors. Second, exposure to and dialogue with a variety of world views can challenge students’ assumptions, facilitate reflection and provide an opportunity for oneto-one teaching encounters. Third, from a teacher educator perspective, engagement in virtual world field trips can provide a space for teachers to model teaching methodologies and model creative learning techniques, thus providing student teachers with an insight into different approaches to teaching.

The World of Nothing

Directory of Open Access Journals (Sweden)

Valery A. Kayukov

2017-11-01

Full Text Available The article presents a comparative analysis of knowledge about the world of nothingness. J. Boehme pointed to the fact that the world of Nothing is everlasting emptiness, where and wherein the material world could emerge. But the thing is that the world of absolute emptiness did not vanish at the moment of beginning of the world, quite the reverse, it has somehow been permanently enlarging. What will happen next is still a question. Perhaps our world will begin to be moving back on a new spiral of development, perhaps a real transition to the world of nothing will have appeared in this subtle place. For the present it is clear that these two worlds have not touched each other in mutually beneficial communication so far, and everything from our world passes into the world of nothing, and in general, the world of nothing ontologically appears to be much more existential than the world of apparent reality. What can give us some kind of key point at least, be some kind of organon in interaction with these two worlds - with the world of Nothing in which there is no matter and which cannot be perceived by any senses, and with the world of matter in which all senses are unstable and changeable? In our opinion, the only beacon and the instrument of knowledge can be the mind. To understand this phenomenon, by benefiting from a comparative methodology, this study investigates opinions of a number of philosophers, J. Boehme, G.V.F. Hegel, M. Heidegger, and J.P. Sartre, on the existence of the world of nothing.

World energy outlook 2004

International Nuclear Information System (INIS)

2004-01-01

The World Energy Outlook is the most complete and authoritative energy publication and has received several prestigious awards from government and industry in recognition of its analytical excellence. The new edition offers: - Analysis: Over 550 pages of detailed analysis with 150 graphs and tables. - Projections: Supply and demand projections to 2030 for oil, gas, coal, renewables, nuclear and electricity, plus projections of energy related CO 2 emissions. -World Alternative Policy Scenario:A detailed assessment of the impact of possible climate change policies and energy efficient technologies. -Russia: An in-depth study of the 'most important energy country'. - Energy and Development: An analysis of energy's role in overcoming world poverty. - Reserves: A detailed analysis of world oil and gas reserves and of the problems involved in measuring them

Wind around the world

International Nuclear Information System (INIS)

Rackstraw, K.

1998-01-01

A combination of cost reductions and progressive policies in key markets kept the world wind market percolating in 1997 with a record 1510 MW of new wind capacity installed, representing annual sales of more than $1.5 billion. This new record surpasses last year''s total by 24 percent, about the average annual rate of growth for the last three years. Worldwide utility-scale wind installations at the end of 1997 totaled 7763 MW. Most activity occurred in Europe, which accounted for over 75 percent of 1997 installations. Germany was again the world''s leading single market, this time by quite a large margin, accounting for more than one-third of the annual total by itself at 532 MW in 1997. The end of 1997 also marked the time at which Germany officially passed the US as the largest total single market with over 2079 MW in total installations versus about 1805 MW for the US, although the US had actually lost the lead by mid-year. Spain is the new addition to the top echelon of world wind markets, installing 215 MW in 1997 that more than doubles their total installed capacity over the previous year and ranks them number three in the world for the year. Denmark''s 1997 total of 300 MW is also a record, although this estimate could go up as the official count is finalized. India, the second largest wind market in 1995 and 1996, slipped several notches because of a variety of factors, including a change in government and a slowdown in the economy. The US wind market continues to stagnate as it has for the last several years, largely because of the uncertainty surrounding restructuring of US electric utilities. The US market is poised for a big comeback in 1998, however

Difficult to foresee tomorrow's world

International Nuclear Information System (INIS)

Anon.

2016-01-01

Some countries like Italy or Kazakhstan have given up nuclear power but others (Viet-Nam, Bangladesh, Egypt, Turkey) have the willingness to enter the nuclear world to sustain their development while complying with their environmental obligations. Others like United Arab Emirates, Belarus have their first reactor being built and other countries like France, Finland, United States, Slovakia, Brazil, Pakistan, India, Taiwan, South-Korea, China, Russia, Ukraine are reinforcing their reactor fleet by building new reactors. A total of 62 reactors is being built throughout the world with 22 in China. New construction of reactors, the dismantling of decommissioned installations and the integration of nuclear power in new economic models make the future brighter for nuclear industry. (A.C.)

The genera Cosmopterix Hübner and Pebobs Hodges in the New World with special attention to the Neotropical fauna (Lepidoptera: Cosmopterigidae)

NARCIS (Netherlands)

Koster, J.C.

2010-01-01

The genera Cosmopterix Hübner, [1825] and Pebobs Hodges, 1978 (Cosmopterigidae) of the New World are revised, for the Neotropical fauna for the first time. A total of 102 species is recognized and 49 species are described as new: Cosmopterix adrastea spec. nov., C. amalthea spec. nov., C. ananke

The World Financial Crisis

OpenAIRE

F. Gerard Adams

2009-01-01

The world financial crisis of 2008 is a consequence of new financial technologies, new accounting methods and new international linkages. These developments have come at a time when governments have returned to an old-fashioned freemarket philosophy. This paper links the systemic financial/economic crisis of 2008 to the new economy developments, globalisation and policy philosophy perspectives of recent decades. It raises the question of how to re-establish confidence once traditional thinkin...

Beyond Bitcoin: The Rise of Blockchain World

DEFF Research Database (Denmark)

Beck, Roman

2018-01-01

The brave new world of blockchain potentially transforms the fi nancial structures we have come to know and feel ambivalent about. What does a decentralized, secure system mean for our society?......The brave new world of blockchain potentially transforms the fi nancial structures we have come to know and feel ambivalent about. What does a decentralized, secure system mean for our society?...

The New World challenge: Performance trends in wine production in major wine-exporting countries in the 2000s and their implications for the Australian wine industry

Directory of Open Access Journals (Sweden)

Euan Fleming

2014-12-01

Full Text Available Anderson, K., Nelgen, S., 2011. Global Wine Markets, 1961 to 2009: A Statistical Compendium. University of Adelaide Press, Adelaide publication of an index of revealed comparative advantage suggests that the Australian wine industry had come under increased competition from other “New World” producers in the first decade of this century. We examine this influence by comparing the transformation of winegrapes into wine volume and value in the 11 largest wine-exporting countries during the years, 2000–2009. Our focus is on the challenge issued by other New World producers from the Southern Hemisphere to Australian producers, and the continuing challenge to Old World global supremacy by New World producers and its response. Four performance measures are used this study. Two key trends are evident. First, all countries migrated to higher price points, albeit with differing degrees of success: slightly declining productivity in transforming winegrapes into wine output was overwhelmed by price/quality effects, leading to substantial gains in transforming winegrapes into wine value. Second, New World producers plus Portugal and Spain were much more successful in achieving gains in their export value proposition than they were in extracting value in their domestic markets. Results show that Australian wine producers had lost some of their competitive advantage during the 2000s as their pre-existing strategy dominated by the export of high-volume wines by large companies at low to medium price points, and their reliance on a reputation for reliable good quality for the price point was beginning to fail in the face of competition from both New World and Old World producers. Acknowledgement of this outcome has led to a good deal of introspection, and recognition of the need to promote the wine regions of Australia, based on higher-quality wines, and to select and promote quality indicators.

Fatal injury epidemiology among the New Zealand military forces in the First World War.

Science.gov (United States)

Wilson, Nick; Summers, Jennifer A; Baker, Michael G; Thomson, George; Harper, Glyn

2013-11-01

Despite the large mortality burden of First World War (WW1) on New Zealand (NZ) military forces, no analysis using modern epidemiological methods has ever been conducted. We therefore aimed to study injury-related mortality amongst NZ military forces in WW1. An electronic version of the Roll-of-Honour for NZ Expeditionary Force (NZEF) personnel was supplemented with further coding and analysed statistically. We also performed literature searches to provide context. Out of a total of 16,703 deaths occurring during the war (28 July 1914 to 11 November 1918), injury deaths predominated: 65.1% were "killed in action" (KIA), 23.4% "died of wounds" (DOW), 1.0% were other injuries (e.g. "accidents", drownings, suicides and executions), and 10.5% were other causes (mainly disease). During the course of the war, the annual mortality rate from injury (for KIA + DOW) per 10,000 NZEF personnel in the North Hemisphere peaked at 1335 in 1915 (Gallipoli campaign) and then peaked again in 1917 at 937 (largely the Battle of Passchendaele). Some of the offensive campaigns involved very high mortality peaks (e.g. 2 days with over 450 deaths per day in October 1917). Participation in First World War was by far the worst fatal injury event in New Zealand's history. Many of these injury deaths could be considered to have been preventable through: better diplomacy (to prevent the war), improved military planning to reduce failed campaigns (e.g. Gallipoli, Passchendaele), earlier use of protective equipment such as helmets, and improved healthcare services.

Advertising in Virtual Worlds: The Example of Second Life

Directory of Open Access Journals (Sweden)

Dincer Atli

2015-07-01

Full Text Available As consumers become decreasingly responsive towards traditional forms of advertising, advertisers are turning towards more innovative methods.  Virtual worlds provide an extraordinary potential for new and enhanced modes of advertising.  This study examines the opportunities of the virtual world, Second Life, as a new platform for businesses’ advertisement and promotional activities. First, we briefly introduce the concept of virtual worlds and virtual advertising. Then, we go on to explain the development of advertising, with special emphasis on its evolution alongside technological developments. Furthermore, we discuss how virtual worlds developed and how the features of these worlds lent themselves to advertising.  Second Life, the most popular virtual world application, is given a special emphasis, and we shall explore opportunities and practices for virtual advertising in this virtual world application.

Hyperglycemia, hypernatremia, and hyperosmolarity in 6 neonatal llamas and alpacas.

Science.gov (United States)

Cebra, C K

2000-12-01

Neonatal camelids can develop hyperglycemia, hypernatremia, and hyperosmolarity in response to a combination of stress and inadequate water intake. Clinical signs of this syndrome include a fine head tremor, ataxia, and a base-wide stance of the hind limbs, but biochemical analyses are necessary to confirm the diagnosis. Camelids appear to be susceptible to this syndrome because of a poor insulin response to hyperglycemia; hypernatremia results from free water loss associated with glucose diuresis. Water loss associated with glucose diuresis may necessitate a higher rate of fluid administration in camelids with this syndrome than is typically used for treatment of hypernatremia in calves.

World's longest underwater line part of new dc transmission link

Energy Technology Data Exchange (ETDEWEB)

1967-04-01

The world's seventh dc transmission system including the world's longest underwater power cable is now operative. The system, linking the Italian Mainland with Sardinia, was designed and engineered by the English Electric Co. Ltd. It will ensure a constant power supply for Sardinia and allow export of 200 MW of power to the Tuscany area in Italy. Proving test began on the link in Decmeber and continued until full demand is made on it from Italy.

Virtual Worlds for Virtual Organizing

Science.gov (United States)

Rhoten, Diana; Lutters, Wayne

The members and resources of a virtual organization are dispersed across time and space, yet they function as a coherent entity through the use of technologies, networks, and alliances. As virtual organizations proliferate and become increasingly important in society, many may exploit the technical architecture s of virtual worlds, which are the confluence of computer-mediated communication, telepresence, and virtual reality originally created for gaming. A brief socio-technical history describes their early origins and the waves of progress followed by stasis that brought us to the current period of renewed enthusiasm. Examination of contemporary examples demonstrates how three genres of virtual worlds have enabled new arenas for virtual organizing: developer-defined closed worlds, user-modifiable quasi-open worlds, and user-generated open worlds. Among expected future trends are an increase in collaboration born virtually rather than imported from existing organizations, a tension between high-fidelity recreations of the physical world and hyper-stylized imaginations of fantasy worlds, and the growth of specialized worlds optimized for particular sectors, companies, or cultures.

New MAGLEV link opens door to world sales

Energy Technology Data Exchange (ETDEWEB)

1981-03-13

When the magnetic levitation people mover-or advanced transit shuttle-linking Birmingham airport with the international railway station opens in 1984, it is expected to be the first revenue-earning system of its kind in the world. The project and the high hopes of its backers for future sales are discussed.

A new edition global map - Uranium deposits of the world

International Nuclear Information System (INIS)

Fairclough, M.

2014-01-01

In 1995 The International Atomic Energy Agency published a hard copy map entitled “World Distribution of Uranium Deposits” at a scale of 1:30 000 000. The map displayed data from agency information that was to become UDEPO database of uranium deposits, overlaid on a generalised geological map supplied by the Geological Survey of Canada. At that time, the database contained 582 deposits with a cut-off of 500 t U at an average grade of 0.03% U, and was generated over a period of half a decade by small group external experts. The experts developed a revised deposit classification scheme displayed on the map and in the accompanying guidebook in 1996. A revised and expanded UDEPO database was made widely available on the internet from 2004, and contained additional deposit information and a constantly increasing number of deposits (874 by the end of 2008 coinciding with a new UDEPO guidebook in 2009). Enhanced efforts by the IAEA and consultants of the UDEPO Working Group have now generated a database that has 1526 deposits with a more detailed classification subdivision utilised in a forthcoming IAEA UDEPO publication. The establishment of this classification scheme and the completion of a major phase of updating UDEPO has created an opportunity for creating a completely new edition of the Uranium Deposits Of The World Map using modern GIS techniques. Cartographic tools within GIS software have become very sophisticated, allowing better display of variably dense data through real-time manipulation of layers and symbology with the GIS dataset. Moreover, some of the results of this functionality can then be transferred to the data display aspects the online version of UDEPO as well as distributed as scale-independent digital version of the map. In parallel, a planned IAEA publication regarding global uranium provinces allows a more rigorous clustering of deposits for the purposes of showing particular metallogenic aspects in more detail. This also has an important

Reality Is Broken to Be Rebuilt: How a Gamer's Mindset Can Show Science Educators New Ways of Contribution to Science and World?

Science.gov (United States)

Farhangi, Sanaz

2012-01-01

This paper presents a review of Jane McGonigal's book, "Reality is broken" (Reality is broken: why games make us better and how they can change the world. Penguin Press, New York, 2011). As the book subtitle suggests it is a book about "why games make us better and how they can change the world", written by a specialist in computer game design. I…

Grooming up the hierarchy: the exchange of grooming and rank-related benefits in a new world primate.

Directory of Open Access Journals (Sweden)

Barbara Tiddi

Full Text Available Seyfarth's model assumes that female primates derive rank-related benefits from higher-ranking females in exchange for grooming. As a consequence, the model predicts females prefer high-ranking females as grooming partners and compete for the opportunity to groom them. Therefore, allogrooming is expected to be directed up the dominance hierarchy and to occur more often between females with adjacent ranks. Although data from Old World primates generally support the model, studies on the relation between grooming and dominance rank in the New World genus Cebus have found conflicting results, showing considerable variability across groups and species. In this study, we investigated the pattern of grooming in wild tufted capuchin females (Cebus apella nigritus in Iguazú National Park, Argentina by testing both the assumption (i.e., that females gain rank-related return benefits from grooming and predictions (i.e., that females direct grooming up the dominance hierarchy and the majority of grooming occurs between females with adjacent ranks of Seyfarth's model. Study subjects were 9 adult females belonging to a single group. Results showed that grooming was given in return for tolerance during naturally occurring feeding, a benefit that higher-ranking females can more easily grant. Female grooming was directed up the hierarchy and was given more often to partners with similar rank. These findings provide supporting evidence for both the assumption and predictions of Seyfarth's model and represent, more generally, the first evidence of reciprocal behavioural interchanges driven by rank-related benefits in New World female primates.

Grooming up the hierarchy: the exchange of grooming and rank-related benefits in a new world primate.

Science.gov (United States)

Tiddi, Barbara; Aureli, Filippo; Schino, Gabriele

2012-01-01

Seyfarth's model assumes that female primates derive rank-related benefits from higher-ranking females in exchange for grooming. As a consequence, the model predicts females prefer high-ranking females as grooming partners and compete for the opportunity to groom them. Therefore, allogrooming is expected to be directed up the dominance hierarchy and to occur more often between females with adjacent ranks. Although data from Old World primates generally support the model, studies on the relation between grooming and dominance rank in the New World genus Cebus have found conflicting results, showing considerable variability across groups and species. In this study, we investigated the pattern of grooming in wild tufted capuchin females (Cebus apella nigritus) in Iguazú National Park, Argentina by testing both the assumption (i.e., that females gain rank-related return benefits from grooming) and predictions (i.e., that females direct grooming up the dominance hierarchy and the majority of grooming occurs between females with adjacent ranks) of Seyfarth's model. Study subjects were 9 adult females belonging to a single group. Results showed that grooming was given in return for tolerance during naturally occurring feeding, a benefit that higher-ranking females can more easily grant. Female grooming was directed up the hierarchy and was given more often to partners with similar rank. These findings provide supporting evidence for both the assumption and predictions of Seyfarth's model and represent, more generally, the first evidence of reciprocal behavioural interchanges driven by rank-related benefits in New World female primates.

High tropical net diversification drives the New World latitudinal gradient in palm (Arecaceae) species richness

DEFF Research Database (Denmark)

Svenning, J.-C.; Borchsenius, Finn; Bjorholm, Stine Wendelboe

2008-01-01

/temperature and water availability. These patterns therefore reflect net diversification at both deep and shallow levels in the phylogeny. Richness also increased with range in elevation, but this was only reflected in the MS/G pattern and therefore reflects recent diversification. Main conclusions The geographical......Aim Species richness exhibits striking geographical variation, but the processes that drive this variation are unresolved. We investigated the relative importance of two hypothesized evolutionary causes for the variation in palm species richness across the New World: time for diversification...

The age and diversification of terrestrial New World ecosystems through Cretaceous and Cenozoic time.

Science.gov (United States)

Graham, Alan

2011-03-01

Eight ecosystems that were present in the Cretaceous about 100 Ma (million years ago) in the New World eventually developed into the 12 recognized for the modern Earth. Among the forcing mechanisms that drove biotic change during this interval was a decline in global temperatures toward the end of the Cretaceous, augmented by the asteroid impact at 65 Ma and drainage of seas from continental margins and interiors; separation of South America from Africa beginning in the south at ca. 120 Ma and progressing northward until completed 90-100 Ma; the possible emission of 1500 gigatons of methane and CO(2) attributed to explosive vents in the Norwegian Sea at ca. 55 Ma, resulting in a temperature rise of 5°-6°C in an already warm world; disruption of the North Atlantic land bridge at ca. 45 Ma at a time when temperatures were falling; rise of the Andes Mountains beginning at ca. 40 Ma; opening of the Drake Passage between South America and Antarctica at ca. 32 Ma with formation of the cold Humboldt at ca. 30 Ma; union of North and South America at ca. 3.5 Ma; and all within the overlay of evolutionary processes. These processes generated a sequence of elements (e.g., species growing in moist habitats within an overall dry environment; gallery forests), early versions (e.g., mangrove communities without Rhizophora until the middle Eocene), and essentially modern versions of present-day New World ecosystems. As a first approximation, the fossil record suggests that early versions of aquatic communities (in the sense of including a prominent angiosperm component) appeared early in the Middle to Late Cretaceous, the lowland neotropical rainforest at 64 Ma (well developed by 58-55 Ma), shrubland/chaparral-woodland-savanna and grasslands around the middle Miocene climatic optimum at ca. 15-13 Ma, deserts in the middle Miocene/early Pliocene at ca. 10 Ma, significant tundra at ca. 7-5 Ma, and alpine tundra (páramo) shortly thereafter when cooling temperatures were augmented

Schrodinger's rabbits the many worlds of quantum

CERN Document Server

Bruce, Colin

2004-01-01

For the better part of a century, attempts to explain what was really going on in the quantum world seemed doomed to failure. But recent technological advances have made the question both practical and urgent. A brilliantly imaginative group of physicists at Oxford University have risen to the challenge. This is their story. At long last, there is a sensible way to think about quantum mechanics. The new view abolishes the need to believe in randomness, long-range spooky forces, or conscious observers with mysterious powers to collapse cats into a state of life or death. But the new understanding comes at a price: we must accept that we live in a multiverse wherein countless versions of reality unfold side-by-side. The philosophical and personal consequences of this are awe-inspiring. The new interpretation has allowed imaginative physicists to conceive of wonderful new technologies: measuring devices that effectively share information between worlds and computers that can borrow the power of other worlds to...

Miller-Urey spark-discharge experiments in the deuterium world

Energy Technology Data Exchange (ETDEWEB)

Cooper, Geoffrey J.T.; Surman, Andrew J.; McIver, Jim; Colon-Santos, Stephanie M.; Gromski, Piotr S.; Buchwald, Saskia; Suarez Marina, Irene; Cronin, Leroy [WestCHEM, School of Chemistry, University of Glasgow (United Kingdom)

2017-07-03

We designed and conducted a series of primordial-soup Miller-Urey style experiments with deuterated gases and reagents to compare the spark-discharge products of a ''deuterated world'' with the standard reaction in the ''hydrogenated world''. While the deuteration of the system has little effect on the distribution of amino acid products, significant differences are seen in other regions of the product-space. Not only do we observe about 120 new species, we also see significant differences in their distribution if the two hydrogen isotope worlds are compared. Several isotopologue matches can be identified in both, but a large proportion of products have no equivalent in the corresponding isotope world with ca. 43 new species in the D world and ca. 39 new species in the H world. This shows that isotopic exchange (the addition of only one neutron) may lead to significant additional complexity in chemical space under otherwise identical reaction conditions. (copyright 2017 The Authors. Published by Wiley-VCH Verlag GmbH and Co. KGaA.)

The world on a collision course and the need for a new economy.

Science.gov (United States)

Max-Neef, Manfred

2010-05-01

The first part of the paper is an attempt to demonstrate that what we are going through at the present time is not just an economic-financial crisis, but a crisis of humanity. It seems that for the first time in human history several crises converge to simultaneously reach their maximum level of tension. The dominant economic model is to a great degree responsible for the world's collision course. Hence a number of myths that sustain the model are listed and analyzed. It is argued that a new economy, coherent with the problematiques of the twenty first century, needs urgently to be devised. The second part proposes the foundations for a new economy based on five fundamental postulates that allow the construction of transdisciplinary, holistic, and systemic visions to adequately understand the interdependence of all the elements that sustain life. It is stressed that it is no longer acceptable that Universities still teach economic theories of the nineteenth century in order to tackle twenty first century problems that have no precedence.

Phylogeny of the Ampelocissus-Vitis clade in Vitaceae supports the New World origin of the grape genus.

Science.gov (United States)

Liu, Xiu-Qun; Ickert-Bond, Stefanie M; Nie, Ze-Long; Zhou, Zhuo; Chen, Long-Qing; Wen, Jun

2016-02-01

The grapes and the close allies in Vitaceae are of great agronomic and economic importance. Our previous studies showed that the grape genus Vitis was closely related to three tropical genera, which formed the Ampelocissus-Vitis clade (including Vitis, Ampelocissus, Nothocissus and Pterisanthes). Yet the phylogenetic relationships of the four genera within this clade remain poorly resolved. Furthermore, the geographic origin of Vitis is still controversial, because the sampling of the close relatives of Vitis was too limited in the previous studies. This study reconstructs the phylogenetic relationships within the clade, and hypothesizes the origin of Vitis in a broader phylogenetic framework, using five plastid and two nuclear markers. The Ampelocissus-Vitis clade is supported to be composed of five main lineages. Vitis includes two described subgenera each as a monophyletic group. Ampelocissus is paraphyletic. The New World Ampelocissus does not form a clade and shows a complex phylogenetic relationship, with A. acapulcensis and A. javalensis forming a clade, and A. erdvendbergiana sister to Vitis. The majority of the Asian Ampelocissus species form a clade, within which Pterisanthes is nested. Pterisanthes is polyphyletic, suggesting that the lamellate inflorescence characteristic of the genus represents convergence. Nothocissus is sister to the clade of Asian Ampelocissus and Pterisanthes. The African Ampelocissus forms a clade with several Asian species. Based on the Bayesian dating and both the RASP and Lagrange analyses, Vitis is inferred to have originated in the New World during the late Eocene (39.4Ma, 95% HPD: 32.6-48.6Ma), then migrated to Eurasia in the late Eocene (37.3Ma, 95% HPD: 30.9-45.1Ma). The North Atlantic land bridges (NALB) are hypothesized to be the most plausible route for the Vitis migration from the New World to Eurasia, while intercontinental long distance dispersal (LDD) cannot be eliminated as a likely mechanism. Copyright © 2015

World Heritage Sites through the Eyes of New Tourists – Who Cares about World Heritage Brand in Budapest?

OpenAIRE

Ivett Sziva; Lia Bassa

2017-01-01

Budapest is one the most emerging tourism destinations in Central-Eastern Europe, and besides the popularity of the regenerated “multicultural and design” district, its cultural heritage, particularly those on the list of the UNESCO World Heritage, assure its growing attractiveness. However the cultural sites are the most visited sightseeing attractions, our proposition was that the tourists are not aware of the fact, that they are visiting UNESCO World Heritage Site (WHS). The main aim of th...

Complex of primary and secondary parasitoids (Hymenoptera: Encyrtidae and Signiphoridae) of Hypogeoccoccus spp. mealybugs (Hemiptera: Pseudococcidae) in the New World

Science.gov (United States)

Parasitoids, both primary and secondary (hyperparasitoids), of Hypogeococcus spp. mealybugs (Hemiptera: Pseudococcidae) are reviewed to report results of the surveys in the New World conducted during 2009–2017 for perspective natural enemies of the Harrisia cactus mealybug, Hypogeococcus sp., which ...

World Employment, 1995. An ILO Report.

Science.gov (United States)

International Labour Office, Geneva (Switzerland).

The impact of globalization of the world economy on employment throughout the world was examined by determining the causes and effects of the reduction in economic growth that has occurred in most developed and developing countries since 1973. The following were among the factors considered: international inequality; new technologies; effects of…

The Old World species of Boehmeria (Urticaceae, tribus Boehmerieae)

DEFF Research Database (Denmark)

Wilmot-Dear, Christine Melanie; Friis, Ib

2013-01-01

This is the second part of a world-wide revision of the genus Boehmeria, the previously-published part having dealt with the New World species. The Old World species are widely distributed in the tropics and subtropics from West Africa to islands in the Pacific Ocean and from Japan and China...... to Southern Africa, Madagascar and Australia, with the highest species richness in the Himalayas and their extension into China and Indochina. No indigenous species is common to both the Old and New World. The species represent taxonomic units of very different complexity: most species exhibit little...

The New World economy. Report addressed to Ms Segolene Royal, Minister of Environment, Sustainable Development and Energy, working group led by Corinne Lepage

International Nuclear Information System (INIS)

Babinet, Gilles; Courousse, Christophe; Croise, Nathalie; Delanoy, Isabelle; Dupres, Stanislas; Ferrari, Romain; Feireira, Victor; Heron, Antoine; Kloboukoff, Charles; Lahiani, Mathias; Le Tyrant, Catherine; Lepercq, Thierry; Maestroni, Myriam; Massias, Louis; Novel, Anne-Sophie; Orru, Serge; Porcher, Thomas; Rapenne, Jean; Roquette, Marc; Siegel, Francois; Spiroux, Joel; Tenzer, Nicolas; Tincq, Benjamin; Tropper, Helene; Zimmer, Daniel; Damerval, Francois; Krabal, Nicolas; Berger, Arnaud

2015-01-01

The New World economy is an economy at the service of mankind, free of fossil and fissile energies, connected and relocated. Everywhere in the world, energy transition is taking place. France is no exception. We have in front of us living proof that an efficient, long-term economy serving the common good and creating employment is not only possible, but also capable to generate enthusiasm and confidence. A newer economic model becomes possible. Synergies are developing in France along this direction. Though, unfortunately, the tipping point has not yet been reached. Still, we have the capacity and it is our duty to commit ourselves to this new economy. The levers to be put in place are now clearly known: giving priority to health and well-being, acknowledging external factors, promoting intangible assets, innovating at the local level, and properly taking demand into account. It is also about bolstering the transformation of entrepreneur-ship already under way, introducing fairness in the economy by agreeing to address the question of profit distribution. Such revolutions imply that the rules of the game will change in the taxation, financial, legislative, and normative fields as well as in the area of vocational training. A number of reforms are recommended in the report: creation of certificates relating to systems of externality to finance the transition, a circular VAT as well as an incentive VAT for organic products and products of the circular economy, and massive development of complementary currencies, alternative financing and civic funds. The report also points to the necessary simplification of rules applicable to start-ups and small innovative companies, the promotion of Green Deals and the development of experimentation, the abolition of standards which favor entrenched privileges, as well as the support for state actors making innovative choices in terms of procurement in the public sector. We thus call for a Green Business Act that can put together

State of the world 1991

International Nuclear Information System (INIS)

Brown, L.R.

1991-01-01

The State of the World report is an annual analysis of the global environment pollutions by human activities. What to do for starting a strong world economy that does not destroy natural resources and ecological systems. This is the question of this book. The ten chapters are: a new world order, designing a viable energy system, reducing wastes and saving materials, rethinking urban transports, reforming forestry, rehabilitation of the East Europe and USSR environments, facing abortion problems, the military and environment, the happy medium, restructuring the global economy. (A.B.). 709 refs., 11 figs., 37 tabs

Young New Zealanders and the Great War: Exploring the Impact and Legacy of the First World War, 1914-2014

Science.gov (United States)

Graham, Jeanine

2008-01-01

Drawing on school histories, published adult recollections, oral interviews and children's letters, this article explores how the lives of young New Zealanders were affected by contemporary attitudes and activities during World War I in a country far removed from the actual theatre of war. Particular emphasis is given to school-related…

New global realities for mining and exploration companies in today's world

International Nuclear Information System (INIS)

Klingner, G.D.

2002-01-01

This paper presented brief comments on the stock market, the economy and the business of mining industry consolidation. It also described the rapidly changing environment within the mining industry and the realities facing mineral resource exploration and development. The mining industry is market-driven. Mining stocks have done well recently, with most movement occurring with major mining companies, particularly gold. However, it was noted that current economic projects have wide ranges of possible errors because the world has become a riskier place in recent months. In 2001, world trade growth slowed to just under 1 per cent, the lowest level since 1982, and global GDP growth fell to 2.4 per cent, a recessionary rate. The GDP grew strongly in China, the world's second largest consumer of mineral-based products. The author suggested that the state of economic recovery in 2002 will depend on how the major industrial economies respond to monetary easing and on how financial and currency markets manage stresses arising from increased levels of indebtedness. It is likely that demand for mineral commodities will be slow and keeping a close control on supply will determine how soon producers will benefit from world economic recovery

Influencia de los defecaderos de camélidos sobre el desarrollo vegetal y riqueza de especies en morrenas glaciales, Tierra del Fuego Camelid defecation influences vegetation development and species richnesss on glacial moraines, Tierra del Fuego

Directory of Open Access Journals (Sweden)

JUAN M. HENRÍQUEZ

2004-09-01

Full Text Available Los escasos trabajos de interacción planta-herbívoro en ambientes severos han concluido que los herbívoros tienen un rol menor sobre el proceso de colonización en los estados tempranos de la sucesión. Aquí se documentan los efectos de defecaderos de un herbívoro ungulado (Lamma guanicoe sobre los patrones vegetales en una intermorrena glacial reciente. Se evaluó la composición florística, frecuencia y síndrome de dispersión de las especies presentes sobre los defecaderos y sitios control. Parámetros de suelo fueron analizados en ambos substratos. La riqueza y diversidad de especies vasculares fueron significativamente mayores sobre los defecaderos. El síndrome de dispersión dominante es la anemocoría en la vegetación de ambos tipos de substratos. Los defecaderos presentan valores superiores de materia orgánica, nitrógeno y fósforo, indicando condiciones localmente más favorables para el establecimiento de plántulas en este ambiente pobre en nutrientes y materia orgánica. Finalmente, se discute acerca de los posibles mecanismos que originan la mayor riqueza y diversidad de especies sobre los defecaderos de guanaco, concluyendo que constituyen una fuente potencial de propágulos que puede acelerar el proceso de colonización en morrenas glaciaresThe few studies of herbivore-plant interaction in severe environments have concluded that the herbivores have a minor role on the process of colonization in the early states of the succession. This paper describes the effects of camelid (Lamma guanicoe dung heaps on vegetation patterns on a recent glacial moraine. Floristic composition, diversity, abundance and dispersion syndrome spectra of the vegetation growing on dung heaps was compared with that of control sites unaffected by camelid defecation. Soil parameters of both substrates were analyzed. Vascular species riches and diversity were significantly higher on dung heaps. Anemochory was the dominant dispersion syndrome on both

World market of nuclear fuel: new capabilities and difficulties

International Nuclear Information System (INIS)

Maks, A.; Kening, R.

1992-01-01

History of beginning, state and development prospects of the world market of nuclear fuel are considered. In detail is discussed the role of countries, being at the former USSR territory, in the uranium production and its market deliveries

Niche conservatism and dispersal limitation cause large-scale phylogenetic structure in the New World palm flora

DEFF Research Database (Denmark)

Eiserhardt, Wolf L.; Svenning, J.-C.; Baker, William J.

similarity decays after speciation depends on the rates of niche evolution and dispersal. If dispersal is slow compared to the tempo of lineage diversification, distributions change little during clade diversification. Phylogenetic niche conservatism precludes distributional shifts in environmental space......, and to the degree that distributions are limited by the niche, also in geographic space. Using phylogenetic turnover methods, we simultaneously analysed the distributions of all New World palms (n=547) and inferred to which degree phylogenetic niche conservatism and dispersal limitation, respectively, caused...

Brazil World Cup Challenges

Directory of Open Access Journals (Sweden)

MANSUR, R.

2012-12-01

Full Text Available Overcoming the productivity challenge is the main benefit of the 2014 World Cup for Brazilian people. The sustainable development of our cultural tourism industry will catapult the new middle class growing up rate.

TRANSLATING THE NEW WORLD(S: A SEMIOTIC APPROACH TO PARROT AND OLIVIER IN AMERICA BY PETER CAREY

Directory of Open Access Journals (Sweden)

Luigi Gussago

2012-12-01

Full Text Available In his latest novel Parrot and Olivier in America (2009 the Australian-born novelist Peter Carey explores the way three seemingly incompatible civilisations translate the New World. On the one hand Olivier, the snobbish French aristocrat, struggles to understand the concept of democracy in America because he wants to translate it ‘literally’ into his own system (of behaviour, social convenience, pragmatics, etc.. On the other hand, Parrot, the British-Australian pícaro and Olivier’s “clown and secretaire”, enjoys rewriting his master’s awful calligraphy, changing some of the Frenchman’s views on America according to his whim, and deliberately acting as a bad translator. Thirdly, the American free citizen, the “Man of the Future” (p. 187: s/he uses language creatively, coining a personal idiolect as evidence of belonging to a nation at its début, where “greed might tear the land apart but still the low could climb so high” (p. 251. This paper aims at illustrating how these three entities translate other systems of values, or their loss of values, into systems with which they can identify. The theoretical framework of my study proceeds from the contributions of Yuri Lotman, the main representative of the Tartu-Moscow school of semiotics.

Comparison of complete mitochondrial DNA sequences between old and new world strains of the cowpea aphid, Aphis craccivora (Hemiptera: Aphididae)

Science.gov (United States)

Mitochondrial DNA provides useful tools for inferring population genetic structure within a species and phylogenetic relationships between species. The complete mitogenome sequences were assembled from strains of the cowpea aphids, Aphis craccivora, from the old (15,308 bp) and new world (15,305 bp...

Pregnancy as protest in interwar British women's writing: an antecedent alternative to Aldous Huxley's Brave New World.

Science.gov (United States)

Bigman, Fran

2016-12-01

Accounts that take Aldous Huxley's Brave New World (1932) as representative of interwar reproductive dystopia fail to recognise that the novel expresses both an interest and an anxiety about the possibility of new reproductive technologies to transform sex, gender, and the family that were widely shared by writers in different genres and perhaps expressed best by those likely to be most affected: women. This article explores three earlier works-Charlotte Haldane's Man's World (1926), Vera Brittain's Halcyon, or the Future of Monogamy (1929), and Naomi Mitchison's Comments on Birth Control (1930)-in which pregnancy, instead of figuring as illness or debility, becomes a form of resistance to the status quo. These works engage with biomedicine, however, rather than abjuring it. Through a reading of these works, this article argues that the intersection of medical humanities and science fiction (SF) can enrich both: medical humanities can push SF to go beyond the canon, and SF can challenge any characterisation of literature in the medical humanities as purely fantastical by demonstrating how it responds to the hopes and anxieties of a particular time. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Withdrawn Amidst the World

DEFF Research Database (Denmark)

Bruun, Mette Birkedal; Nørgaard, Lars Cyril; Nagelsmit, Eelco

2017-01-01

The pious Élisabeth d'Orléans, Mme de Guise, had a vivid correspondence with Armand-Jean de Rancé, abbot of the Cistercian abbey of La Trappe in Normandy. Rancé was considered a champion of unconditional isolation from the world by his contemporaries, but in fact he recommended quite diverse forms...... in remarkable detail how the Duchess should balance her obligations to God and human beings by being a model of withdrawal. To this end she must constantly, in action and demeanour, display to the world her withdrawal from the world. Rancé's spiritual advice to Mme de Guise throws new light on the devotional...... horizon of Gaston d'Orléans's daughter and the pastoral practice of the abbot of La Trappe. Above all, it shows the intricacies and modulations of the withdrawal from the world prescribed to late seventeenth-century aristocratic dévots and, especially, dévotes....

World Class Teachers.

Science.gov (United States)

Mitchell, Rosalita

1998-01-01

School communities are challenged to find ways to identify good teachers and give other teachers a chance to learn from them. The New Mexico World Class Teacher Project is encouraging teachers to pursue certification by the National Board for Professional Teaching Standards. This process sharpens teachers' student assessment skills and encourages…

New approach to small scale power could light up much of the developing world

Energy Technology Data Exchange (ETDEWEB)

Brooks, J.

2011-01-15

The modern conveniences requiring electricity have been out of reach for almost half of the world's population because they live too far from the grid. Innovative technology combined with creative new business models could significantly improve the quality of life for millions of people. This article discussed a small scale renewable energy system that could ensure that villages all over the world have access to radios, lights, refrigeration and other critical technologies. The article also noted the potential implications in terms of health, education and the general standard of living for millions of people. The basic model involves setting up small solar panels in a good location in a village or on a farm. The panels can be used to charge up equipment that is either on-site or portable. This article described how to achieve economies of scale through mass production of many similar units. The project has been tested in Brazil and a donation to the project of $100,000 will be used to install a solar-powered public infrastructure comprised of water pumping, school and an Internet station. The funds will also be used to provide 70 solar lanterns for children living in two villages on the Rio Tapajos, a tributary to the Amazon near Santarem. 1 fig.

Analysis of the predictive qualities of betting odds and FIFA World Ranking: evidence from the 2006, 2010 and 2014 Football World Cups.

Science.gov (United States)

Wunderlich, Fabian; Memmert, Daniel

2016-12-01

The present study aims to investigate the ability of a new framework enabling to derive more detailed model-based predictions from ranking systems. These were compared to predictions from the bet market including data from the World Cups 2006, 2010, and 2014. The results revealed that the FIFA World Ranking has essentially improved its predictive qualities compared to the bet market since the mode of calculation was changed in 2006. While both predictors were useful to obtain accurate predictions in general, the world ranking was able to outperform the bet market significantly for the World Cup 2014 and when the data from the World Cups 2010 and 2014 were pooled. Our new framework can be extended in future research to more detailed prediction tasks (i.e., predicting the final scores of a match or the tournament progress of a team).

Rethinking project management: A structured literature review with a critical look at the brave new world

DEFF Research Database (Denmark)

Svejvig, Per; Andersen, Peter

2015-01-01

This paper presents the results of a structured review of the rethinking project management (RPM) literature based on the classification and analysis of 74 contributions and in addition takes a critical look at this brave new world. Through the analysis, a total of 6 overarching categories emerged......: contextualization, social and political aspects, rethinking practice, complexity and uncertainty, actuality of projects and broader conceptualization. These categories cover a broad range of different contributions with diverse and alternative perspectives on project management. The early RPM literature dates back...

The new world of retirement income security in America.

Science.gov (United States)

Quinn, Joseph F; Cahill, Kevin E

2016-01-01

We have entered a new world of retirement income security in America, with older individuals more exposed to market risk and more vulnerable to financial insecurity than prior generations. This reflects an evolution that has altered the historical vision of a financially secure retirement supported by Social Security, a defined-benefit pension plan, and individual savings. Today, 2 of these 3 retirement income sources-pensions and savings-are absent or of modest importance for many older Americans. Retirement income security now often requires earnings from continued work later in life, which exacerbates the economic vulnerability of certain segments of the population, including persons with disabilities, the oldest-old, single women, and individuals with intermittent work histories. Because of the unprecedented aging of our society, further changes to the retirement income landscape are inevitable, but policymakers do have options to help protect the financial stability of older Americans. We can begin by promoting savings at all (especially younger) ages and by removing barriers that discourage work later in life. For individuals already on the cusp of retirement, more needs to be done to educate the public about the value of delaying the receipt of Social Security benefits. Inaction now could mean a return to the days when old age and poverty were closely linked. The negative repercussions of this would extend well beyond traditional economic measures, as physical and mental health outcomes are closely tied to financial security. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Cross-correlations and influence in world gold markets

Science.gov (United States)

Lin, Min; Wang, Gang-Jin; Xie, Chi; Stanley, H. Eugene

2018-01-01

Using the detrended cross-correlation analysis (DCCA) coefficient and the detrended partial cross-correlation analysis (DPCCA) coefficient, we investigate cross-correlations and net cross-correlations among five major world gold markets (London, New York, Shanghai, Tokyo, and Mumbai) at different time scales. We propose multiscale influence measures for examining the influence of individual markets on other markets and on the entire system. We find (i) that the cross-correlations, net cross-correlations, and net influences among the five gold markets vary across time scales, (ii) that the cross-market correlation between London and New York at each time scale is intense and inherent, meaning that the influence of other gold markets on the London-New York market is negligible, (iii) that the remaining cross-market correlations (i.e., those other than London-New York) are greatly affected by other gold markets, and (iv) that the London gold market significantly affects the other four gold markets and dominates the world-wide gold market. Our multiscale findings give market participants and market regulators new information on cross-market linkages in the world-wide gold market.

Corporate planning in the new world order

International Nuclear Information System (INIS)

Vaasjo, B.T.

1996-01-01

The planning process at IPL Energy Inc. was discussed. IPL Energy is the largest natural gas distribution company which has the world's longest and most complex liquid pipeline. The three business units at IPL Energy are: gas distribution, pipelines, and international investment. Each uses different strategies for growth opportunities. The process wherein the plans from the various business units are formulated, leavened with corporate level vision, enriched by the addition of an international dimension, and merged into a complex strategic plan for the company as a whole has been described. The need for flexibility, and the importance of constant attention to the three Cs -competencies, culture and communications - were emphasized

The World Science Festival

Science.gov (United States)

Pazmino, J.

2012-06-01

(Abstract only) New York City in the late 20th century rose to be a planetary capital for the sciences, not just astronomy. This growth was mainly in the academic sector but a parallel growth occurred in the public and home field. With the millennium crossing, scientists in New York agitated for a celebration of the City as a place for a thriving science culture. In 2008 they began World Science Festival. 2011 is the fourth running, on June 1-5, following the AAVSO/AAS meetings. World Science Festival was founded by Dr. Brian Greene, Columbia University, and is operated through the World Science Foundation. The Festival is "saturation science" all over Manhattan in a series of lectures, shows, exhibits, performances. It is staged in "science" venues like colleges and musea, but also in off-science spaces like theaters and galleries. It is a blend from hard science, with lectures like those by us astronomers, to science-themed works of art, dance, music. Events are fitted for the public, either for free or a modest fee. While almost all events are on Manhattan, effort has been made to geographically disperse them, even to the outer boroughs. The grand finale of World Science Festival is a street fair in Washington Square. Science centers in booths, tents, and pavilions highlight their work. In past years this fair drew 100,000 to 150,000 visitors. The entire Festival attracts about a quarter-million attendees. NYSkies is a proud participant at the Washington Square fair. It interprets the "Earth to the Universe" display, debuting during IYA-2009. Attendance at "Earth..." on just the day of the fair plausibly is half of all visitors in America. The presentation shows the scale and scope of World Science Festival, its relation to the City, and how our astronomers work with it.

Perancangan Interior Nestlé's Cereal World Di Surabaya

OpenAIRE

Mariana Wibowo, Linda Gunawan

2014-01-01

Nestlé's Cereal World is a new facility in foodservice industry, which people can explore and obtain a new experience about cereal through 4 main facilities: attraction, discover, dining, and shopping. Nestlé's Cereal World design will use Nestlé's interior branding, which the tangible and intangible design will represent the Nestlé's Cereal identity.

Complex biogeographic scenarios revealed in the diversification of the largest woodpecker radiation in the New World.

Science.gov (United States)

Navarro-Sigüenza, Adolfo G; Vázquez-Miranda, Hernán; Hernández-Alonso, Germán; García-Trejo, Erick A; Sánchez-González, Luis A

2017-07-01

Phylogenetic relationships and patterns of evolution within Melanerpes, one of the most diverse groups of New World woodpeckers (22-23 lineages), have been complicated due to complex plumages and morphological adaptations. In an attempt to resolve these issues, we obtained sequence data from four nuclear introns and two mitochondrial protein-coding genes for 22 of the 24 currently recognized species in the genus. We performed phylogenetic analyses involving Maximum Likelihood and Bayesian Inference, species-tree divergence dating, and biogeographic reconstructions. Tree topologies from the concatenated and species-tree analyses of the mtDNA and nDNA showed broadly similar patterns, with three relatively well-supported groups apparent: (a) the Sphyrapicus clade (four species); (b) the typical Melanerpes clade, which includes temperate and subtropical dry forest black-backed species; and (c) the mostly barred-backed species, here referred to as the "Centurus" clade. The phylogenetic position of Melanerpes superciliaris regarding the rest of Melanerpes is ambiguous as it is recovered as sister to the rest of Melanerpes or as sister to a group including Sphyrapicus+Melanerpes. Our species tree estimations recovered the same well-delimited highly-supported clades. Geographic range evolution (estimated in BioGeoBEARS) was best explained by a DIVALIKE+j model, which includes vicariance, founder effect speciation, and anagenetic dispersal (range expansion) as important processes involved in the diversification of the largest radiation of woodpeckers in the New World. Copyright © 2017 Elsevier Inc. All rights reserved.

Genome-wide diversity and differentiation in New World populations of the human malaria parasite Plasmodium vivax.

Science.gov (United States)

de Oliveira, Thais C; Rodrigues, Priscila T; Menezes, Maria José; Gonçalves-Lopes, Raquel M; Bastos, Melissa S; Lima, Nathália F; Barbosa, Susana; Gerber, Alexandra L; Loss de Morais, Guilherme; Berná, Luisa; Phelan, Jody; Robello, Carlos; de Vasconcelos, Ana Tereza R; Alves, João Marcelo P; Ferreira, Marcelo U

2017-07-01

The Americas were the last continent colonized by humans carrying malaria parasites. Plasmodium falciparum from the New World shows very little genetic diversity and greater linkage disequilibrium, compared with its African counterparts, and is clearly subdivided into local, highly divergent populations. However, limited available data have revealed extensive genetic diversity in American populations of another major human malaria parasite, P. vivax. We used an improved sample preparation strategy and next-generation sequencing to characterize 9 high-quality P. vivax genome sequences from northwestern Brazil. These new data were compared with publicly available sequences from recently sampled clinical P. vivax isolates from Brazil (BRA, total n = 11 sequences), Peru (PER, n = 23), Colombia (COL, n = 31), and Mexico (MEX, n = 19). We found that New World populations of P. vivax are as diverse (nucleotide diversity π between 5.2 × 10-4 and 6.2 × 10-4) as P. vivax populations from Southeast Asia, where malaria transmission is substantially more intense. They display several non-synonymous nucleotide substitutions (some of them previously undescribed) in genes known or suspected to be involved in antimalarial drug resistance, such as dhfr, dhps, mdr1, mrp1, and mrp-2, but not in the chloroquine resistance transporter ortholog (crt-o) gene. Moreover, P. vivax in the Americas is much less geographically substructured than local P. falciparum populations, with relatively little between-population genome-wide differentiation (pairwise FST values ranging between 0.025 and 0.092). Finally, P. vivax populations show a rapid decline in linkage disequilibrium with increasing distance between pairs of polymorphic sites, consistent with very frequent outcrossing. We hypothesize that the high diversity of present-day P. vivax lineages in the Americas originated from successive migratory waves and subsequent admixture between parasite lineages from geographically diverse sites

Vom work Book Journal, 2011 1st Edition PDF

African Journals Online (AJOL)

USER

American camelids: Llama, Alpaca, Vicuno, nd. Guanaco. 2 edition, Iowa State University Press,. Iowa, U.S.A.. SASTRY, G.A. AND RAMA, P.R. (2004): Veterinary th pathology. 7 edition, Satish Kumar Jain, New Delhi,. India. SAYED, S.M.; RATEB, H.Z.; ARAFA M.I.; ABDEL-HAFEEZ. M.M. AND AMER A.A (2007): Field study ...

New Evidences for Early Paracas Textiles and Ceramics at Cerrillos, Ica Valley, Perú

OpenAIRE

Splitstoser, Jeffrey; Wallace, Dwight D.; Delgado, Mercedes

2012-01-01

Cerrillos is an Early to Middle Paracas civic-ceremonial site located in the upper Ica Valley of Perú. The site is known for its finely plastered adobe architecture, beautifully decorated ceramics, and complex textiles, many of which are decorated with camelid hair. Cerrillos was located in a strategically important place where the mountains meet the coastal desert and the Ica River bends south, a likely intersection in a road system that connected Cerrillos to contemporary sites in the Parac...

VACCINES AND IMMUNIZATION: WORLD SITUATION

Directory of Open Access Journals (Sweden)

G.H. Brundtland

2007-01-01

Full Text Available The last issue of the report «vaccines and immunization: world situation» stresses considerable success in immunization at the global level since the mid 90 s — completely total eradication of poliomyelitis across the world, as well as the drastic reduction of the new measles and tetanus cases among mothers and newborns in some poor countries. The report also briefly describes the progress in the development and implementation of the new life saving vaccines, which may save millions of lives annually. The authors have explained some of the reasons, why the global community should invest in immunization, as well as the perspectives for the use of vaccines and immunization in future.Key words: vaccine, immunization, children.

A word from the DG: A new opening to the world

CERN Multimedia

2007-01-01

Having just returned from a visit to India and China I'm conscious of something that has changed greatly in the way CERN works over recent years, and is continuing rapidly to evolve. Today, CERN provides for collaboration not only among European states, but among states the world over. Joining CERN's 20 European member states are six observers and a further 35 countries that have signed cooperation agreements with us. Furthermore we have a number of memoranda of understanding with scientific agencies around the world. And among our user community, you will find representatives of 111 nationalities. There is no other organization in the world quite like it, where people of so many different cultures and backgrounds work harmoniously towards common goals. The LHC project has allowed CERN to take international collaboration in science beyond the regional model that it pioneered in the 1950s, blazing the trail for future global projects in science. Although over 90% funded by our Member States, the LHC is the f...

First discovery of the charophycean green alga Lychnothamnus barbatus (Charophyceae) extant in the New World.

Science.gov (United States)

Karol, Kenneth G; Skawinski, Paul M; McCourt, Richard M; Nault, Michelle E; Evans, Reesa; Barton, Martha E; Berg, Matthew S; Perleberg, Donna J; Hall, John D

2017-07-27

Although some species of Characeae, known as stoneworts, can be found on every continent except Antarctica, many species and some genera have limited geographic distributions. The genus Lychnothamnus , represented by a single extant species L. barbatus , was known only from scattered localities in Europe and Australasia until it was recently discovered in North America. Morphological identifications were made from specimens collected in Minnesota and Wisconsin, USA. DNA sequences were obtained for three plastid-encoded genes ( atpB , psbC , rbcL ) from seven putative Lychnothamnus samples from two states in the USA Distribution and abundance were estimated in each lake using point intercept surveys where surveyors sampled aquatic vegetation. Fourteen lakes in Wisconsin and two lakes in Minnesota, USA, were found to harbor Lychnothamnus barbatus . These represent the first report of this rare charophycean extant in the New World. The North American specimens matched the morphological description for L. barbatus and were compared directly with the neotype. Phylogenetic results using three plastid-encoded genes confirmed the identification placing New World samples with those from Europe and Australasia. Our phylogenetic analyses also confirmed the sister relationship between L. barbatus and Nitellopsis obtusa . Because this taxon is not known for aggressive invasiveness in its native range, it may have existed in heretofore-undiscovered native populations, although the possibility that it is a recent introduction cannot be eliminated. The potential for discovery of novel lineages of green algae in even well-studied regions is apparently far from exhausted. © 2017 Karol et al. Published by the Botanical Society of America. This work is licensed under a Creative Commons Attribution License (CC-BY-NC).

Biology and systematics of the New World Phyllocnistis Zeller leafminers of the avocado genus Persea (Lepidoptera, Gracillariidae).

Science.gov (United States)

Davis, Donald R; Wagner, David L

2011-05-11

Four New World species of Phyllocnistis Zeller are described from serpentine mines in Persea (Family Lauraceae). Phyllocnistis hyperpersea,new species, mines the upper leaf surfaces of avocado, Persea americana Mill., and red bay, Persea borbonia (L.) Spreng. and ranges over much of the southeastern United States into Central America. Phyllocnistis subpersea,new species, mines the underside and occasionally upper sides of new leaves of Persea borbonia in southeastern United States. Phyllocnistis longipalpa, new species, known only from southern Florida also mines the undersides of new leaves of Persea borbonia. Phyllocnistis perseafolia,new species, mines both leaf surfaces and possibly fruits of Persea americana in Colombia, South America. As in all known species of Phyllocnistis, the early instars are subepidermal sapfeeders in young (not fully hardened) foliage, and the final instar is an extremely specialized, nonfeeding larval form, whose primary function is to spin the silken cocoon, at the mine terminus, prior to pupation. Early stages are illustrated and described for three of the species. The unusual morphology of the pupae, particularly the frontal process of the head, is shown to be one of the most useful morphological sources of diagnostic characters for species identification of Phyllocnistis. COI barcode sequence distances are provided for the four proposed species and a fifth, undescribed species from Costa Rica.

Tenable world strategies

Energy Technology Data Exchange (ETDEWEB)

Meadows, D.L. (New Hampshire Univ. (USA). Inst. for Policy and Social Science Research)

1991-10-01

The Author presents several arguments explaining and backing the mechanics of a world strategy of zero growth. First, attention is brought to Aurelio Peccei's concerns regarding the short-sightedness of the energy and economic policies of industrialized nations. In his book (entitled 'Verso l'Abisso'), written almost 25 years ago, he correctly predicted the severity and timing of current global environmental problems such as the greenhouse effect and acid rain. Urgent and concerted action by world governments is recommended to contain and and remedy damage being caused by a diverse mix of integrated factors - over-population, uncontrolled food production, pollution, over-production by industry, and the improper use of energy and other natural resources. The Author sets guidelines for the creation of a world of steady-state growth in which an equilibrium is reached between overall standards of living and population dynamics. To meet this goal of global man/environment peaceful coexistence, he strongly urges the creation and instillation of a new set of values through the placing of emphasis on the research and development of cultural, psychological, institutional and moral philosophies which, in the last century, have been almost entirely supplanted world-wide by growing materialistic ideals and the pursuit of technological perfection.

A Programme for the Eradication of the New World Screwworm from North Africa

Energy Technology Data Exchange (ETDEWEB)

NONE

1990-04-15

The recent establishment of the New World Screwworm (NWS), Cochliomyia hominivorax, in North Africa poses an enormous threat to that continent, as well as the Mediterranean Basin and the Middle East. Because of the urgent need to initiate an eradication programme as soon as possible, three consultants met in Vienna from 8 to 19 January 1990 to prepare a programme outlining the eradication of the NWS from North Africa. Emphasis was placed on the Sterile Insect Technique (SIT) portion of an eradication programme. At the time the report was prepared the NWS had been reported only from Libya, therefore the report deals with eradication from that country. The document will be used by the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture as a guide to assist FAO in NWS eradication from North Africa.

A Programme for the Eradication of the New World Screwworm from North Africa

International Nuclear Information System (INIS)

1990-04-01

The recent establishment of the New World Screwworm (NWS), Cochliomyia hominivorax, in North Africa poses an enormous threat to that continent, as well as the Mediterranean Basin and the Middle East. Because of the urgent need to initiate an eradication programme as soon as possible, three consultants met in Vienna from 8 to 19 January 1990 to prepare a programme outlining the eradication of the NWS from North Africa. Emphasis was placed on the Sterile Insect Technique (SIT) portion of an eradication programme. At the time the report was prepared the NWS had been reported only from Libya, therefore the report deals with eradication from that country. The document will be used by the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture as a guide to assist FAO in NWS eradication from North Africa.

Phylogeny and chronology of the major lineages of New World hystricognath rodents: insights on the biogeography of the Eocene/Oligocene arrival of mammals in South America.

Science.gov (United States)

Voloch, Carolina M; Vilela, Julio F; Loss-Oliveira, Leticia; Schrago, Carlos G

2013-04-22

The hystricognath rodents of the New World, the Caviomorpha, are a diverse lineage with a long evolutionary history, and their representation in South American fossil record begins with their occurrence in Eocene deposits from Peru. Debates regarding the origin and diversification of this group represent longstanding issues in mammalian evolution because early hystricognaths, as well as Platyrrhini primates, appeared when South American was an isolated landmass, which raised the possibility of a synchronous arrival of these mammalian groups. Thus, an immediate biogeographic problem is posed by the study of caviomorph origins. This problem has motivated the analysis of hystricognath evolution with molecular dating techniques that relied essentially on nuclear data. However, questions remain about the phylogeny and chronology of the major caviomorph lineages. To enhance the understanding of the evolution of the Hystricognathi in the New World, we sequenced new mitochondrial genomes of caviomorphs and performed a combined analysis with nuclear genes. Our analysis supports the existence of two major caviomorph lineages: the (Chinchilloidea + Octodontoidea) and the (Cavioidea + Erethizontoidea), which diverged in the late Eocene. The Caviomorpha/phiomorph divergence also occurred at approximately 43 Ma. We inferred that all family-level divergences of New World hystricognaths occurred in the early Miocene. The molecular estimates presented in this study, inferred from the combined analysis of mitochondrial genomes and nuclear data, are in complete agreement with the recently proposed paleontological scenario of Caviomorpha evolution. A comparison with recent studies on New World primate diversification indicate that although the hypothesis that both lineages arrived synchronously in the Neotropics cannot be discarded, the times elapsed since the most recent common ancestor of the extant representatives of both groups are different.

A Brave New World: Students Debate Ethics of Biotechnology.

Science.gov (United States)

Barksdale, Francia

1996-01-01

This article describes an interdisciplinary classroom project in which ninth graders simulate a "World Council on Genetic Technology." Students in small groups take on the persona and interests of individuals from specific countries in the group effort to develop a covenant for regulating the use of biotechnology. The benefits of having gifted…

[Science fiction and the Brave New World: predictions fulfilled in our century and bioethical considerations].

Science.gov (United States)

Santos, Ana Carolina Clemente Dos; Amorim Neto, Thomaz Pereira de; Goes, Andrea Carla de Souza

2013-06-01

The speed with which science generates results in modern society requires reflection on the limits of scientific progress. This is the foundation of Brave New World, a book published by Aldous Huxley in 1932 that portrays a future technological society along the lines of Fordism. This article establishes a relationship between our current technocratic society and that described by Huxley, discussing the viability of the technical and biological aspects of the manipulations narrated in the book in light of current knowledge. Some bioethical considerations with respect to the procedures 'invented' by the author - and which are already or could be developed in modern society - will also be addressed.

Mass Communications in the Third World: Some Ethical Considerations.

Science.gov (United States)

Lent, John A.

In the past five years, unprecedented discussion and analysis have been focused on mass media in the third world. Common topics include development journalism, the New Information Order, cultural invasion and exchange, and ruralization of media. Ethical considerations for first world involvement in third world media have arisen in several areas.…

Shattering world assumptions: A prospective view of the impact of adverse events on world assumptions.

Science.gov (United States)

Schuler, Eric R; Boals, Adriel

2016-05-01

Shattered Assumptions theory (Janoff-Bulman, 1992) posits that experiencing a traumatic event has the potential to diminish the degree of optimism in the assumptions of the world (assumptive world), which could lead to the development of posttraumatic stress disorder. Prior research assessed the assumptive world with a measure that was recently reported to have poor psychometric properties (Kaler et al., 2008). The current study had 3 aims: (a) to assess the psychometric properties of a recently developed measure of the assumptive world, (b) to retrospectively examine how prior adverse events affected the optimism of the assumptive world, and (c) to measure the impact of an intervening adverse event. An 8-week prospective design with a college sample (N = 882 at Time 1 and N = 511 at Time 2) was used to assess the study objectives. We split adverse events into those that were objectively or subjectively traumatic in nature. The new measure exhibited adequate psychometric properties. The report of a prior objective or subjective trauma at Time 1 was related to a less optimistic assumptive world. Furthermore, participants who experienced an intervening objectively traumatic event evidenced a decrease in optimistic views of the world compared with those who did not experience an intervening adverse event. We found support for Shattered Assumptions theory retrospectively and prospectively using a reliable measure of the assumptive world. We discuss future assessments of the measure of the assumptive world and clinical implications to help rebuild the assumptive world with current therapies. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Geopolitics of petroleum. A new market. New risks. New worlds; Geopolitique du petrole. Un nouveau marche. De nouveaux risques. Des nouveaux mondes

Energy Technology Data Exchange (ETDEWEB)

Lestrange, C. de; Paillard, Ch.A.; Zelenko, P

2005-02-01

The aim of this book is to shade light on a complex world in complete evolution, the stakes of which for today's societies being proportional to the energy and economical importance of petroleum. The big petroleum fear of consuming countries and the reactions linked with oil shocks are now old stories. The producing countries are today at least as vulnerable to price variations and fluxes restrictions as the consumers of developed countries. Two countries, USA and Saudi Arabia, and one organisation, the OPEC, play a key role in the regulation of this system, the equilibrium of which is now threatened by the reinforcement of preoccupations like environment and human rights protection. New challenges occur: the increase of demand, the concentration of offer, some technological changes that would limit the petroleum needs in the future, and the increasing insecurity of key oil-producing regions. At a shorter term, the geopolitical context of Middle-East is the most worrying. (J.S.)

What Will An Integrated Socialist World Look Like? Brief comments on Warren Wagar ' s article: "Toward a Praxisof a World Integration"

Directory of Open Access Journals (Sweden)

Maria A. Pozas

2015-08-01

Full Text Available World integration under a single state is foreseen by world -system theorists as the only means to save the world from destruction and chaos. The exhaustion of capitalism will lead, in their view, to the substitution of the current system of competing sovereign states by a democratic,liberal and socialist commonwealth. In his article Warren Wagar discusses who will lead this transition, and indirectly suggests that a world system party similar to that of his novel A Short History of the Future (1992 may be the most feasible way to guarantee the socialist character of the new world state.

General Theory of Duality. A proposal to unifiy relativity theory, quantum mechanics and string theory - cognition for a new dynamic world view in physics

International Nuclear Information System (INIS)

Harder, M.

2005-01-01

The chase after a world formula is presently the most iridescent task for natural science. By the development of a radical new scientistic theory, unifying not only relativity and quantum theory as also astrophysics and string theory to a common view, the author lances the first serious candidate for a TOE (Theory of Everything) in the scientific discussion. The General Theory of Duality (GDT) offers not only surprising answers to fundamental questions of physics, but also discovers the smallest component of our universe, which is still known since a longer time, which we ignored: Planck's Constant. May be possible that by this book a new world view in physics can be created. (GL)

Withdrawn Amidst the World

DEFF Research Database (Denmark)

Bruun, Mette Birkedal; Nørgaard, Lars Cyril; Nagelsmit, Eelco

2017-01-01

The pious Élisabeth d'Orléans, Mme de Guise, had a vivid correspondence with Armand-Jean de Rancé, abbot of the Cistercian abbey of La Trappe in Normandy. Rancé was considered a champion of unconditional isolation from the world by his contemporaries, but in fact he recommended quite diverse form...... horizon of Gaston d'Orléans's daughter and the pastoral practice of the abbot of La Trappe. Above all, it shows the intricacies and modulations of the withdrawal from the world prescribed to late seventeenth-century aristocratic dévots and, especially, dévotes.......The pious Élisabeth d'Orléans, Mme de Guise, had a vivid correspondence with Armand-Jean de Rancé, abbot of the Cistercian abbey of La Trappe in Normandy. Rancé was considered a champion of unconditional isolation from the world by his contemporaries, but in fact he recommended quite diverse forms...... in remarkable detail how the Duchess should balance her obligations to God and human beings by being a model of withdrawal. To this end she must constantly, in action and demeanour, display to the world her withdrawal from the world. Rancé's spiritual advice to Mme de Guise throws new light on the devotional...

Innovation at UNICEF: How to Help Balance an Asymmetric World

KAUST Repository

Fabian, Christopher

2017-01-10

Using science, technology, and venture investment to help balance an asymmetric world How do we find solutions to the greatest challenges facing humanity? UNICEF\\'s Office of Innovation (www.unicefstories.org) helps the world\\'s leading children\\'s organization use new methods and approaches to identify, invest in, and scale open source technologies that benefit children, and the world. This talk will share our approach to developing solutions to billion-person problems - a hybrid between the world of Silicon Valley venture capital and the world of global development, policy, and governmental change. Chris will discuss using data, science, and failure to drive investment and development decisions, as well as issues in developing good companies that also want to do good. Examples from Uganda, Estonia, China, Nigeria, and more show that new portfolios of (sometimes surprisingly simple) technologies can create global collaborations around issues important to us all.

VISUALIZATION OF VGI DATA THROUGH THE NEW NASA WEB WORLD WIND VIRTUAL GLOBE

Directory of Open Access Journals (Sweden)

M. A. Brovelli

2016-06-01

Full Text Available GeoWeb 2.0, laying the foundations of Volunteered Geographic Information (VGI systems, has led to platforms where users can contribute to the geographic knowledge that is open to access. Moreover, as a result of the advancements in 3D visualization, virtual globes able to visualize geographic data even on browsers emerged. However the integration of VGI systems and virtual globes has not been fully realized. The study presented aims to visualize volunteered data in 3D, considering also the ease of use aspects for general public, using Free and Open Source Software (FOSS. The new Application Programming Interface (API of NASA, Web World Wind, written in JavaScript and based on Web Graphics Library (WebGL is cross-platform and cross-browser, so that the virtual globe created using this API can be accessible through any WebGL supported browser on different operating systems and devices, as a result not requiring any installation or configuration on the client-side, making the collected data more usable to users, which is not the case with the World Wind for Java as installation and configuration of the Java Virtual Machine (JVM is required. Furthermore, the data collected through various VGI platforms might be in different formats, stored in a traditional relational database or in a NoSQL database. The project developed aims to visualize and query data collected through Open Data Kit (ODK platform and a cross-platform application, where data is stored in a relational PostgreSQL and NoSQL CouchDB databases respectively.

Visualization of Vgi Data Through the New NASA Web World Wind Virtual Globe

Science.gov (United States)

Brovelli, M. A.; Kilsedar, C. E.; Zamboni, G.

2016-06-01

GeoWeb 2.0, laying the foundations of Volunteered Geographic Information (VGI) systems, has led to platforms where users can contribute to the geographic knowledge that is open to access. Moreover, as a result of the advancements in 3D visualization, virtual globes able to visualize geographic data even on browsers emerged. However the integration of VGI systems and virtual globes has not been fully realized. The study presented aims to visualize volunteered data in 3D, considering also the ease of use aspects for general public, using Free and Open Source Software (FOSS). The new Application Programming Interface (API) of NASA, Web World Wind, written in JavaScript and based on Web Graphics Library (WebGL) is cross-platform and cross-browser, so that the virtual globe created using this API can be accessible through any WebGL supported browser on different operating systems and devices, as a result not requiring any installation or configuration on the client-side, making the collected data more usable to users, which is not the case with the World Wind for Java as installation and configuration of the Java Virtual Machine (JVM) is required. Furthermore, the data collected through various VGI platforms might be in different formats, stored in a traditional relational database or in a NoSQL database. The project developed aims to visualize and query data collected through Open Data Kit (ODK) platform and a cross-platform application, where data is stored in a relational PostgreSQL and NoSQL CouchDB databases respectively.

Going to extremes: contrasting rates of diversification in a recent radiation of new world passerine birds.

Science.gov (United States)

Barker, F Keith; Burns, Kevin J; Klicka, John; Lanyon, Scott M; Lovette, Irby J

2013-03-01

Recent analyses suggest that a few major shifts in diversification rate may be enough to explain most of the disparity in diversity among vertebrate lineages. At least one significant increase in diversification rate appears to have occurred within the birds; however, several nested lineages within birds have been identified as hyperdiverse by different studies. A clade containing the finches and relatives (within the avian order Passeriformes), including a large radiation endemic to the New World that comprises ~8% of all bird species, may be the true driver of this rate increase. Understanding the patterns and processes of diversification of this diverse lineage may go a long way toward explaining the apparently rapid diversification rates of both passerines and of birds as a whole. We present the first multilocus phylogenetic analyses of this endemic New World radiation of finch relatives that include sampling of all recognized genera, a relaxed molecular clock analysis of its divergence history, and an analysis of its broad-scale diversification patterns. These analyses recovered 5 major lineages traditionally recognized as avian families, but identified an additional 10 relatively ancient lineages worthy of recognition at the family level. Time-calibrated diversification analyses suggested that at least 3 of the 15 family-level lineages were significantly species poor given the entire group's background diversification rate, whereas at least one-the tanagers of family Thraupidae-appeared significantly more diverse. Lack of an age-diversity relationship within this clade suggests that, due to rapid initial speciation, it may have experienced density-dependent ecological limits on its overall diversity.

WorldWideScience.org: Bringing Light to Grey

OpenAIRE

Hitson, Brian A. (OSTI-DOE); Johnson, Lorrie A. (OSTI-DOE); GreyNet, Grey Literature Network Service

2008-01-01

WorldWideScience.org and its governance structure, the WorldWideScience Alliance, are putting a brighter spotlight on grey literature. Through this new tool, grey literature is getting broader exposure to audiences all over the world. Improved access to and sharing of research information is the key to accelerating progress and breakthroughs in any field, especially science. Includes: Conference preprint, Powerpoint presentation, Abstract and Biographical notes, Pratt student commentary ...

Faculty Perspectives of Faculty Persona in a Virtual World

Science.gov (United States)

Blackmon, Stephanie J.

2013-01-01

Immersive virtual worlds provide a new way to deliver online courses or parts of online and face-to-face courses. There is a growing body of research on online learning, and the data on virtual worlds is also increasing. However, literature concerning professors' experiences with specific aspects of virtual worlds is limited. For example,…

A Multiplex Real-Time PCR Assay to Diagnose and Separate Helicoverpa armigera and H. zea (Lepidoptera: Noctuidae) in the New World.

Science.gov (United States)

Gilligan, Todd M; Tembrock, Luke R; Farris, Roxanne E; Barr, Norman B; van der Straten, Marja J; van de Vossenberg, Bart T L H; Metz-Verschure, Eveline

2015-01-01

The Old World bollworm, Helicoverpa armigera (Hübner), and the corn earworm, H. zea (Boddie), are two of the most important agricultural pests in the world. Diagnosing these two species is difficult-adults can only be separated with a complex dissection, and larvae cannot be identified to species using morphology, necessitating the use of geographic origin for identification in most instances. With the discovery of H. armigera in the New World, identification of immature Helicoverpa based on origin is no longer possible because H. zea also occurs in all of the geographic regions where H. armigera has been discovered. DNA barcoding and restriction fragment length polymorphism (RFLP) analyses have been reported in publications to distinguish these species, but these methods both require post-PCR processing (i.e., DNA sequencing or restriction digestion) to complete. We report the first real-time PCR assay to distinguish these pests based on two hydrolysis probes that bind to a segment of the internal transcribed spacer region 2 (ITS2) amplified using a single primer pair. One probe targets H. armigera, the second probe targets H. zea, and a third probe that targets a conserved segment of 18S rDNA is used as a control of DNA quality. The assay can be completed in 50 minutes when using isolated DNA and is successfully tested on larvae intercepted at ports of entry and adults captured during domestic surveys. We demonstrate that the assay can be run in triplex with no negative effects on sensitivity, can be run using alternative real-time PCR reagents and instruments, and does not cross react with other New World Heliothinae.

A Multiplex Real-Time PCR Assay to Diagnose and Separate Helicoverpa armigera and H. zea (Lepidoptera: Noctuidae in the New World.

Directory of Open Access Journals (Sweden)

Todd M Gilligan

Full Text Available The Old World bollworm, Helicoverpa armigera (Hübner, and the corn earworm, H. zea (Boddie, are two of the most important agricultural pests in the world. Diagnosing these two species is difficult-adults can only be separated with a complex dissection, and larvae cannot be identified to species using morphology, necessitating the use of geographic origin for identification in most instances. With the discovery of H. armigera in the New World, identification of immature Helicoverpa based on origin is no longer possible because H. zea also occurs in all of the geographic regions where H. armigera has been discovered. DNA barcoding and restriction fragment length polymorphism (RFLP analyses have been reported in publications to distinguish these species, but these methods both require post-PCR processing (i.e., DNA sequencing or restriction digestion to complete. We report the first real-time PCR assay to distinguish these pests based on two hydrolysis probes that bind to a segment of the internal transcribed spacer region 2 (ITS2 amplified using a single primer pair. One probe targets H. armigera, the second probe targets H. zea, and a third probe that targets a conserved segment of 18S rDNA is used as a control of DNA quality. The assay can be completed in 50 minutes when using isolated DNA and is successfully tested on larvae intercepted at ports of entry and adults captured during domestic surveys. We demonstrate that the assay can be run in triplex with no negative effects on sensitivity, can be run using alternative real-time PCR reagents and instruments, and does not cross react with other New World Heliothinae.

A light-connected world

Science.gov (United States)

Haas, Harald

2016-08-01

The humble household light bulb - once a simple source of illumination - could soon be transformed into the backbone of a revolutionary new wireless communications network based on visible light. Harald Haas explains how this “LiFi” system works and how it could shape our increasingly data-driven world

“The Godly Greedy Appetite”: New Relic Circulation in the Early Modern World

Directory of Open Access Journals (Sweden)

Igor Pérez Tostado

2017-05-01

Full Text Available Having lost all monasteries and a good deal of its medieval Christian movable assets, England became one of the greatest producers of new Catholic relics during the sixteenth and seventeenth centuries. This article aims to look, from a material point of view, at the circulation and consumption of English relics on the Catholic continent. In this case, these products were created because of violence and circulated as an answer to it. Gifts and the exchange of relics served to obtain support for the exiled Catholics and for the institutions providing for their education created in the continent, and allowed them to participate in the necropolitics of the Spanish Monarchy. Relics, artifacts and printed and manuscript narratives brought back from all over the world helped construct a selfimage of an English Catholic as a necrocommunity imbued by a sense of historical continuity and connected to a global imagined community.

Biology and systematics of the New World Phyllocnistis Zeller leafminers of the avocado genus Persea (Lepidoptera, Gracillariidae

Directory of Open Access Journals (Sweden)

Donald Davis

2011-05-01

Full Text Available Four New World species of Phyllocnistis Zeller are described from serpentine mines in Persea (Family Lauraceae. Phyllocnistis hyperpersea, new species, mines the upper leaf surfaces of avocado, Persea americana Mill., and red bay, Persea borbonia (L. Spreng. and ranges over much of the southeastern United States into Central America. Phyllocnistis subpersea, new species, mines the underside and occasionally upper sides of new leaves of Persea borbonia in southeastern United States. Phyllocnistis longipalpa, new species, known only from southern Florida also mines the undersides of new leaves of Persea borbonia. Phyllocnistis perseafolia, new species, mines both leaf surfaces and possibly fruits of Persea americana in Colombia, South America. As in all known species of Phyllocnistis, the early instars are subepidermal sapfeeders in young (not fully hardened foliage, and the final instar is an extremely specialized, nonfeeding larval form, whose primary function is to spin the silken cocoon, at the mine terminus, prior to pupation. Early stages are illustrated and described for three of the species. The unusual morphology of the pupae, particularly the frontal process of the head, is shown to be one of the most useful morphological sources of diagnostic characters for species identification of Phyllocnistis. COI barcode sequence distances are provided for the four proposed species and a fifth, undescribed species from Costa Rica.

A New World Engendered: Intersections. The Making of the Iberian Transatlantic Empires – XVI to XIX Centuries

Directory of Open Access Journals (Sweden)

Verena Stolke

2006-01-01

Full Text Available This article approaches the intersections developed under the colonial Spanish empire among gender relations, feminine sexuality concepts, family honor and State regulation. The way the multiple moral, social, juridical and religious norms in relation to sexuality and relations between women and men interacted with the social/political inequalities in the Iberian colonial experience will be analyzed. The New World provides a particularly clear example of the dynamic intersections between contemporary ideas and ideals about sex/gender and race/ethnicity and social class that became manifest on the new identification systems, classification and social discrimination forged in the consolidation of the Iberian American colonial society. It also becomes an example of the consequences that the sexual morality and the prevailing gender stereotypes have had in all the aspects of women’s lives.

The genera Cosmopterix Hübner and Pebobs Hodges in the New World with special attention to the Neotropical fauna (Lepidoptera: Cosmopterigidae)

OpenAIRE

Koster, J.C.

2010-01-01

The genera Cosmopterix Hübner, [1825] and Pebobs Hodges, 1978 (Cosmopterigidae) of the New World are revised, for the Neotropical fauna for the first time. A total of 102 species is recognized and 49 species are described as new: Cosmopterix adrastea spec. nov., C. amalthea spec. nov., C. ananke spec. nov., C. argentifera spec. nov., C. aurotegulae spec. nov., C. beckeri spec. nov., C. callisto spec. nov., C. carpo spec. nov., C. chaldene spec. nov., C. chalupae spec. nov., C. erinome spec. n...

The corbiculate bees arose from New World oil-collecting bees: implications for the origin of pollen baskets.

Science.gov (United States)

Martins, Aline C; Melo, Gabriel A R; Renner, Susanne S

2014-11-01

The economically most important group of bees is the "corbiculates", or pollen basket bees, some 890 species of honeybees (Apis), bumblebees (Bombus), stingless bees (Meliponini), and orchid bees (Euglossini). Molecular studies have indicated that the corbiculates are closest to the New World genera Centris, with 230 species, and Epicharis, with 35, albeit without resolving the precise relationships. Instead of concave baskets, these bees have hairy hind legs on which they transport pollen mixed with floral oil, collected with setae on the anterior and middle legs. We sampled two-thirds of all Epicharis, a third of all Centris, and representatives of the four lineages of corbiculates for four nuclear gene regions, obtaining a well-supported phylogeny that has the corbiculate bees nested inside the Centris/Epicharis clade. Fossil-calibrated molecular clocks, combined with a biogeographic reconstruction incorporating insights from the fossil record, indicate that the corbiculate clade arose in the New World and diverged from Centris 84 (72-95)mya. The ancestral state preceding corbiculae thus was a hairy hind leg, perhaps adapted for oil transport as in Epicharis and Centris bees. Its replacement by glabrous, concave baskets represents a key innovation, allowing efficient transport of plant resins and large pollen/nectar loads and freeing the corbiculate clade from dependence on oil-offering flowers. The transformation could have involved a novel function of Ubx, the gene known to change hairy into smooth pollen baskets in Apis and Bombus. Copyright © 2014 Elsevier Inc. All rights reserved.

A Brief Review of the Modern Development of the World and Life in the Works of Scientists of Bryansk Philosophical School of Social-Technogenic World Development

Directory of Open Access Journals (Sweden)

Trifankov Yuriy

2016-01-01

Full Text Available The history of the formation of Bryansk scientific and philosophical school, which has gained high prestige in Russia, is considered. The school explores the issues of formation of the new direction of society development, known as technogenic, and a new direction of development of the world, called as a social-technogenic one, on the basis of science and technology. School representatives use a new methodological approach – a socio-natural one, which origin dates back to the works of V.I.Vernadsky, who regarded the problems of formation of the new world of the biosphere - the noosphere. The authors of this research direction come to the conclusion that the biosphere is being destructed and a postbiospheric world is being built. The technogenic world means transition of mankind from the biosphere to the technosphere, translating biological processes into it as a result of the creation of bio-technology industries. The most important discovery of the school is the change of life evolution on the Earth from the biosphere and biological, which has existed for about 4 billion years, to a socio-techno-natural one. Such a shift could lead to the destruction of biosphere life and formation of a new life shell – postbiosphere, if people follow the spontaneous market development of the world.

Assessing the Value of Real-life Brands in Virtual Worlds

DEFF Research Database (Denmark)

Mattsson, Jan; Barnes, Stuart; Hartley, Nicole

2015-01-01

World. A key finding is the difficulty in creating emotional brand value in Second Life which has serious implications for the sustainability of current real-life brands in Virtual Worlds. The paper rounds off with conclusions and implications for future research and practice in this very new area.......Virtual Worlds are a significant new market environment for brand-building through experiential customer service interactions. Using value theory, this paper aims to assess the experiential brand value of real-life brands that have moved to the Virtual World of Second Life. A key premise...... is that current brand offerings in Virtual Worlds do not offer consumers adequate experiential value. The results demonstrate both the validity of an axiological approach to examining brand value, and highlight significant problems in consumer perceptions of the experiential value of brands within the Virtual...

A local-world evolving hypernetwork model

International Nuclear Information System (INIS)

Yang Guang-Yong; Liu Jian-Guo

2014-01-01

Complex hypernetworks are ubiquitous in the real system. It is very important to investigate the evolution mechanisms. In this paper, we present a local-world evolving hypernetwork model by taking into account the hyperedge growth and local-world hyperedge preferential attachment mechanisms. At each time step, a newly added hyperedge encircles a new coming node and a number of nodes from a randomly selected local world. The number of the selected nodes from the local world obeys the uniform distribution and its mean value is m. The analytical and simulation results show that the hyperdegree approximately obeys the power-law form and the exponent of hyperdegree distribution is γ = 2 + 1/m. Furthermore, we numerically investigate the node degree, hyperedge degree, clustering coefficient, as well as the average distance, and find that the hypernetwork model shares the scale-free and small-world properties, which shed some light for deeply understanding the evolution mechanism of the real systems. (interdisciplinary physics and related areas of science and technology)

Beyond aridification: multiple explanations for the elevated diversification of cacti in the New World Succulent Biome.

Science.gov (United States)

Hernández-Hernández, Tania; Brown, Joseph W; Schlumpberger, Boris O; Eguiarte, Luis E; Magallón, Susana

2014-06-01

Succulent plants are widely distributed, reaching their highest diversity in arid and semi-arid regions. Their origin and diversification is thought to be associated with a global expansion of aridity. We test this hypothesis by investigating the tempo and pattern of Cactaceae diversification. Our results contribute to the understanding of the evolution of New World Succulent Biomes. We use the most taxonomically complete dataset currently available for Cactaceae. We estimate divergence times and utilize Bayesian and maximum likelihood methods that account for nonrandom taxonomic sampling, possible extinction scenarios and phylogenetic uncertainty to analyze diversification rates, and evolution of growth form and pollination syndrome. Cactaceae originated shortly after the Eocene-Oligocene global drop in CO2 , and radiation of its richest genera coincided with the expansion of aridity in North America during the late Miocene. A significant correlation between growth form and pollination syndrome was found, as well as a clear state dependence between diversification rate, and pollination and growth-form evolution. This study suggests a complex picture underlying the diversification of Cactaceae. It not only responded to the availability of new niches resulting from aridification, but also to the correlated evolution of novel growth forms and reproductive strategies. © 2014 The Authors. New Phytologist © 2014 New Phytologist Trust.

Long-term strategies in world energy supply

International Nuclear Information System (INIS)

Haefele, W.

1980-01-01

The International Institute for Applied Systems Analysis of Laxenburg, Austria has carried out a comprehensive systems analysis in which the problems of the long-term world energy supply are treated first qualitatively and then quantiatively. The results of this five-year study have been published in a book entitled 'Energy in a Finite World: a Global Energy Systems Analysis.' This summary of the book indicates that the world's energy supply in the next fifty years will not be limited by resources, but the rates at which new technologies will be built up. (orig.) [de

Testing the Waters: From Moringa Seeds to Fruit Peels, Researchers Are Seeking Out New Ways to Clean Up the World?s Drinking Water.

Science.gov (United States)

Yan, Wudan

2017-01-01

Water on Earth-in our oceans, rivers, lakes, and wetlands-might seem plentiful, but water that is clean and safe enough to drink actually isn't so abundant. Nearly one in ten people still lacks access to safe water worldwide, according to the World Health Organization. In some of the world's most remote and impoverished communities, people live with no taps, showers, flushing toilets, or nearby springs, making it difficult to keep water supplies safe from bacteria, chemicals, and particulates. Moreover, access to clean drinking water isn't just a problem in the developing world; groundwater in developed countries is typically used far more quickly than it is being replenished. As the world population rises, growing numbers of thirsty people could exacerbate already-scant resources.

World spinors revisited

International Nuclear Information System (INIS)

Sijacki, Dj.

1998-01-01

World spinors are objects that transform w.r.t. double covering group Diff(4, R) of the Group of General Coordinate Transformations. The basic mathematical results and the corresponding physical interpretation concerning these, infinite-dimensional, spinorial representations are reviewed. The role of groups Diff(4, R), GA(4, R), GL(4, R), SL(4, R), SO(3,1) and the corresponding covering groups is pointed out. New results on the infinite dimensionality of spinorial representations, explicit construction of the SL(4, R) representations in the basis of finite-dimensional non-unitary SL(2, C) representations, SL(4, R) representation regrouping of tonsorial and spinorial fields of an arbitrary spin Lagrangian field theory, as well as its SL(5, R) generalization in the case of infinite-component world spinor and tensor field theories are presented. (author)

Genome-wide diversity and differentiation in New World populations of the human malaria parasite Plasmodium vivax.

Directory of Open Access Journals (Sweden)

Thais C de Oliveira

2017-07-01

Full Text Available The Americas were the last continent colonized by humans carrying malaria parasites. Plasmodium falciparum from the New World shows very little genetic diversity and greater linkage disequilibrium, compared with its African counterparts, and is clearly subdivided into local, highly divergent populations. However, limited available data have revealed extensive genetic diversity in American populations of another major human malaria parasite, P. vivax.We used an improved sample preparation strategy and next-generation sequencing to characterize 9 high-quality P. vivax genome sequences from northwestern Brazil. These new data were compared with publicly available sequences from recently sampled clinical P. vivax isolates from Brazil (BRA, total n = 11 sequences, Peru (PER, n = 23, Colombia (COL, n = 31, and Mexico (MEX, n = 19.We found that New World populations of P. vivax are as diverse (nucleotide diversity π between 5.2 × 10-4 and 6.2 × 10-4 as P. vivax populations from Southeast Asia, where malaria transmission is substantially more intense. They display several non-synonymous nucleotide substitutions (some of them previously undescribed in genes known or suspected to be involved in antimalarial drug resistance, such as dhfr, dhps, mdr1, mrp1, and mrp-2, but not in the chloroquine resistance transporter ortholog (crt-o gene. Moreover, P. vivax in the Americas is much less geographically substructured than local P. falciparum populations, with relatively little between-population genome-wide differentiation (pairwise FST values ranging between 0.025 and 0.092. Finally, P. vivax populations show a rapid decline in linkage disequilibrium with increasing distance between pairs of polymorphic sites, consistent with very frequent outcrossing. We hypothesize that the high diversity of present-day P. vivax lineages in the Americas originated from successive migratory waves and subsequent admixture between parasite lineages from geographically

Genome-wide diversity and differentiation in New World populations of the human malaria parasite Plasmodium vivax

Science.gov (United States)

de Oliveira, Thais C.; Rodrigues, Priscila T.; Menezes, Maria José; Gonçalves-Lopes, Raquel M.; Bastos, Melissa S.; Lima, Nathália F.; Barbosa, Susana; Gerber, Alexandra L.; Loss de Morais, Guilherme; Berná, Luisa; Phelan, Jody; Robello, Carlos; de Vasconcelos, Ana Tereza R.

2017-01-01

Background The Americas were the last continent colonized by humans carrying malaria parasites. Plasmodium falciparum from the New World shows very little genetic diversity and greater linkage disequilibrium, compared with its African counterparts, and is clearly subdivided into local, highly divergent populations. However, limited available data have revealed extensive genetic diversity in American populations of another major human malaria parasite, P. vivax. Methods We used an improved sample preparation strategy and next-generation sequencing to characterize 9 high-quality P. vivax genome sequences from northwestern Brazil. These new data were compared with publicly available sequences from recently sampled clinical P. vivax isolates from Brazil (BRA, total n = 11 sequences), Peru (PER, n = 23), Colombia (COL, n = 31), and Mexico (MEX, n = 19). Principal findings/Conclusions We found that New World populations of P. vivax are as diverse (nucleotide diversity π between 5.2 × 10−4 and 6.2 × 10−4) as P. vivax populations from Southeast Asia, where malaria transmission is substantially more intense. They display several non-synonymous nucleotide substitutions (some of them previously undescribed) in genes known or suspected to be involved in antimalarial drug resistance, such as dhfr, dhps, mdr1, mrp1, and mrp-2, but not in the chloroquine resistance transporter ortholog (crt-o) gene. Moreover, P. vivax in the Americas is much less geographically substructured than local P. falciparum populations, with relatively little between-population genome-wide differentiation (pairwise FST values ranging between 0.025 and 0.092). Finally, P. vivax populations show a rapid decline in linkage disequilibrium with increasing distance between pairs of polymorphic sites, consistent with very frequent outcrossing. We hypothesize that the high diversity of present-day P. vivax lineages in the Americas originated from successive migratory waves and subsequent admixture between

World Bioenergy 2012. Proceedings

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-11-01

The conference of 2012 had contributions on the following themes: A: World Pellets 2012, B: Market outlook, C: Energy systems, D: Transportation, E: World biorefinery 2012, F: Sustainable bioenergy day. 52 contributions in A - D. A: World Pellets 2012 is an integrated part of World Bioenergy 2012. A three day 'conference in the conference' covering all aspects of pellets: raw material potentials, innovative pellets production systems, torrefaction, new combustion technologies, trade and market development, health and safety aspects, etc. B) Market outlook: Policy and targets for renewable energy to find an alternative to fossil energy are being put in place, increasing the demand for sustainable modern bioenergy. Global trade and improved logistics open up to the markets. To facilitate international trade in bioenergy commodities, new trading places and indexes are needed, as well as generally accepted standards. Supply and demand must meet to guarantee stable prices. In this session you learn all about current market development, including drivers like incentives and policies. C) Energy Systems: Modern bioenergy is a young industry. Therefore, technical development is rapid, with many new innovations. This session focuses on technical development in the whole bioenergy chain, from harvesting of forest residues to combustion technologies and co-firing. Optimal use of biomass through district heating or cooling - small scale and large scale - and CHP technology for electricity production. D) Transportation: Sustainable transports are one of the key challenges of tomorrow. Can we transport biomass as well as other products sustainably and at what costs? Which are the future fuels for transports and when will biofuels be viewed as profitable? Biofuels for transport are under rapid development with new methods, producers and feedstock entering the markets. The future biofuels will be produced in biorefineries, to increase profitability and optimize feed

Credit of ecological interactions: A new conceptual framework to support conservation in a defaunated world.

Science.gov (United States)

Genes, Luísa; Cid, Bruno; Fernandez, Fernando A S; Pires, Alexandra S

2017-03-01

As defaunation spreads through the world, there is an urgent need for restoring ecological interactions, thus assuring ecosystem processes. Here, we define the new concept of credit of ecological interactions , as the number of interactions that can be restored in a focal area by species colonization or reintroduction. We also define rewiring time , as the time span until all the links that build the credit of ecological interactions of a focal area have become functional again. We expect that the credit will be gradually cashed following refaunation in rates that are proportional to (1) the abundance of the reintroduced species (that is expected to increase in time since release), (2) the abundance of the local species that interact with them, and (3) the traits of reintroduced species. We illustrated this approach using a theoretical model and an empirical case study where the credit of ecological interactions was estimated. This new conceptual framework is useful for setting reintroduction priorities and for evaluating the success of conservation initiatives that aim to restore ecosystem services.

Oil and gas activities of the world bank

International Nuclear Information System (INIS)

Hossein, R.

1993-01-01

The oil crisis of the 1970s profoundly challenged the economies of most developing countries. The crisis hit the the oil-importing countries severely, and many suffered deteriorating balances of payments and increasingly unmanageable import bills. It was in this context, in July 1977, that the World Bank's Executive Directors approved an expanded program of lending to assist the Bank's client countries in developing their own energy resources. In 1978, the Bonn Summit and the Secretary General of the United Nations endorsed the initiation of new approaches in the energy sector by the World Bank, particularly in financing oil exploration in countries that were significant oil importers. The new initiative led to a rapid expansion of the World Bank's lending for oil and gas projects, which reached about $1 billion in 1983

Opinion: Composition Studies Saves the World!

Science.gov (United States)

Bizzell, Patricia

2009-01-01

Stanley Fish in his new book ["Save the World on Your Own Time" (New York: Oxford UP,2008)] says that composition studies presents "the clearest example" of what is desperately wrong in the academy, because in writing classrooms, he says, "more often than not anthologies of provocative readings take center stage and the actual teaching of writing…

Trematode diversity in freshwater fishes of the Globe II: 'New World'.

Science.gov (United States)

Choudhury, Anindo; Aguirre-Macedo, M Leopoldina; Curran, Stephen S; de Núñez, Margarita Ostrowski; Overstreet, Robin M; de León, Gerardo Pérez-Ponce; Santos, Cláudia Portes

2016-03-01

We provide a summary overview of the diversity of trematode parasites in freshwater fishes of the 'New World', i.e. the Americas, with emphasis on adult forms. The trematode fauna of three regions, South America, Middle America, and USA and Canada (North America north of Mexico), are considered separately. In total, 462 trematode species have been reported as adults from the Americas. The proportion of host species examined for parasites varies widely across the Americas, from a high of 45% in the Mexican region of Middle America to less than 5% in South America. North and South America share no adult species, and one exclusively freshwater genus, Creptotrema Travassos, Artigas & Pereira, 1928 in the Allocreadiidae Looss, 1902 is the most widely distributed. Metacercariae of strigeiforms maturing in fish-eating birds (e.g. species of the Diplostomidae Poirier, 1886) are common and widely distributed. The review also highlights the paucity of known life-cycles. The foreseeable future of diversity studies belongs to integrative approaches and the application of molecular ecological methods. While opportunistic sampling will remain important in describing and cataloguing the trematode fauna, a better understanding of trematode diversity and biology will also depend on strategic sampling throughout the Americas.

Online worlds as media and communication format

DEFF Research Database (Denmark)

2009-01-01

Digital media and network communication technology have not changed this setup, but rather have opened the possibility for encountering and experiencing additional types of worlds and performing additional types of spatial practices. Being situated online and being globally networked with the pos......Digital media and network communication technology have not changed this setup, but rather have opened the possibility for encountering and experiencing additional types of worlds and performing additional types of spatial practices. Being situated online and being globally networked...... with the possibility of both synchronous and asynchronous communication, digitally mediated worlds provide possible interactions between users which are radically more independent of time and place than the ones facilitated by older media. From this perspective, the concept of online worlds both challenges...... and broadens our understanding of how media shape the world and how the media technology creates new social structures...

The first whole genome and transcriptome of the cinereous vulture reveals adaptation in the gastric and immune defense systems and possible convergent evolution between the Old and New World vultures.

Science.gov (United States)

Chung, Oksung; Jin, Seondeok; Cho, Yun Sung; Lim, Jeongheui; Kim, Hyunho; Jho, Sungwoong; Kim, Hak-Min; Jun, JeHoon; Lee, HyeJin; Chon, Alvin; Ko, Junsu; Edwards, Jeremy; Weber, Jessica A; Han, Kyudong; O'Brien, Stephen J; Manica, Andrea; Bhak, Jong; Paek, Woon Kee

2015-10-21

The cinereous vulture, Aegypius monachus, is the largest bird of prey and plays a key role in the ecosystem by removing carcasses, thus preventing the spread of diseases. Its feeding habits force it to cope with constant exposure to pathogens, making this species an interesting target for discovering functionally selected genetic variants. Furthermore, the presence of two independently evolved vulture groups, Old World and New World vultures, provides a natural experiment in which to investigate convergent evolution due to obligate scavenging. We sequenced the genome of a cinereous vulture, and mapped it to the bald eagle reference genome, a close relative with a divergence time of 18 million years. By comparing the cinereous vulture to other avian genomes, we find positively selected genetic variations in this species associated with respiration, likely linked to their ability of immune defense responses and gastric acid secretion, consistent with their ability to digest carcasses. Comparisons between the Old World and New World vulture groups suggest convergent gene evolution. We assemble the cinereous vulture blood transcriptome from a second individual, and annotate genes. Finally, we infer the demographic history of the cinereous vulture which shows marked fluctuations in effective population size during the late Pleistocene. We present the first genome and transcriptome analyses of the cinereous vulture compared to other avian genomes and transcriptomes, revealing genetic signatures of dietary and environmental adaptations accompanied by possible convergent evolution between the Old World and New World vultures.

Review of the World Bank Road Safety website.

NARCIS (Netherlands)

Maas, J.M.

2006-01-01

The Road Safety website of The World Bank needs to be redeveloped. The website should reflect the new developments in the work field and the IT policy of The World Bank and support its implementation. The report is meant as a brief business case, describing the target audience, purposes of the site,

The World Nuclear Industry Status Report: 1992

International Nuclear Information System (INIS)

Flavin, Christopher; Lenssen, Nicholas; Froggatt, Antony; Willis, John; Kondakji, Assad; Schneider, Mycle

1992-05-01

The World Nuclear Industry Status Report provides a comprehensive overview of nuclear power plant data, including information on operation, production and construction. The WNISR assesses the status of new-build programs in current nuclear countries as well as in potential newcomer countries. This first WNISR Report was issued in 1992 in a joint publication with WISE-Paris, Greenpeace International and the World Watch Institute, Washington

World nuclear fuel market. Eighteenth annual meeting

International Nuclear Information System (INIS)

Anon.

1991-01-01

The papers presented at the eighteenth World Nuclear Fuels Market meeting are cataloged separately. This volume includes information on the following areas of interest: world uranium enrichment capacity and enriched uranium inventories; the impact of new enrichment technologies; predictions of future market trends; non-proliferation aspects of nuclear trade; and a debate as to whether uranium can be successfully traded on a commodities exchange

World coking coal markets

International Nuclear Information System (INIS)

McCloskey, G.

2010-01-01

This article discussed conditions in world coking coal markets. There is increased demand from Asia for metallurgical coal imports. World iron production was up 22 percent in first 7 months of 2010. Supply is up in Australia, the United States, Canada, New Zealand, Russia, and Mongolia, but the unexpected surge in supply caused prices to drop following a robust start to the year. Coking coal exports are up for the United States and Australia, but a delay in expanded production is expected until 2014. There is increased demand from Brazil, India, Taiwan, South Korea, and Japan as well as new plants in Thailand, Indonesia, and Brazil. Unexpectedly, Australia is backing out of the Chinese market but increasing exports to Japan and South Korea. India is seeing flat performance in iron production and imports, and the United States has surged back into Asia. A considerable increase is expected in the seaborne import requirement by 2020. Prices are expected to fall and then rise. This presentation also discussed whether coking coal index pricing is impossible or inevitable. 3 tabs., 5 figs.

The Future of the World Economy is an Integrated World Economic Structure

Directory of Open Access Journals (Sweden)

Sergey Yurievich Glazyev

2018-03-01

Full Text Available Global changes in the modern world cannot be adequately described on the basis of neoliberal thinking and require a new approach. It can be formed on the basis of the cyclical-wave characterization of the development of mankind. The hypothesis about the wave-like development of the world economy with a certain cyclicity lies at the heart of thisresearch. The authors determined the economic basis of the formation, development and change of these waves (technological ways and technical revolutions. These changes reflect in the cyclical fluctuations of the world economy.The mechanism of these fluctuations is described by the theory of “large cycles of the economic conjuncture” by N. Kondratiev. The authors propose a methodology and methodological tools for analyzing and forecasting cyclic-wave processes in the economic development. The study has concluded that it is the regularities of K-cycles that allow one to correctly assess the ongoing processes in the world economy, to forecast possible variants of their development. The authors came to the conclusion that the development of the world economic structure is necessarily accompanied by a cyclical shift in the instruments of capital accumulation (material and financial expansion. These processes are reflected in the periodic replacement of scientific paradigms of economic development and management. The state always takes an active part in the phase of the dominance of productive capital, and the ideological paradigm is of a directing nature. While in the phase of domination of financial capital the liberal paradigm becomes dominant. We have substantiated the thesis about the transition from the American to the Asian systemic cycle of capital accumulation, which would inevitably lead in the middle of the 21st century to the shift of the center of the world economy from the West to the East. The paper concludes that the world is facing a change from the Monopolistic world economic structure to

NATO strategy in a new world order

International Nuclear Information System (INIS)

Guertner, G.L.

1992-01-01

This paper reports that the most immediate threat to Western Europe during the cold ware was the specter of Soviet military superiority looming from the East, proscribing Western political and economic freedom. NATO and the link to U.S. military power deterred political intimidation as well as a less probable military thrust into Central Europe. But these threat have faded under Mikhail Gorbachev, replaced by revolutions in Eastern Europe, the dissolution of the Warsaw Pact, receding Soviet military power, German unification, and the stirring of political and economic freedom nurtured by the West. These events are linked directly to the Gorbachev domestic revolution, a revolution that depends not only on domestic change, but also on political-economic integration with the West and dramatic shifts from defense to domestic investment. New Soviet military thinking, arms control, and unilateral cuts in conventional force structure and dramatic in themselves. But when projected on a new map of Europe, these events call for a major reexamination of NATO military strategy and the future role of the U.S. armed forces in a revised organization. A new strategy for NATO has been quietly taking shape since 1989, the debate often muffled by more dramatic events in the Soviet Union and more recently by war in the Persian Gulf. By the spring of 1991, the broad outlines of a new NATO within a radically new European security regime began to emerge. This chapter assesses both the emerging new strategy and the larger European security environment in which it will evolve

PET Imaging of Macrophage Mannose Receptor-Expressing Macrophages in Tumor Stroma Using 18F-Radiolabeled Camelid Single-Domain Antibody Fragments.

Science.gov (United States)

Blykers, Anneleen; Schoonooghe, Steve; Xavier, Catarina; D'hoe, Kevin; Laoui, Damya; D'Huyvetter, Matthias; Vaneycken, Ilse; Cleeren, Frederik; Bormans, Guy; Heemskerk, Johannes; Raes, Geert; De Baetselier, Patrick; Lahoutte, Tony; Devoogdt, Nick; Van Ginderachter, Jo A; Caveliers, Vicky

2015-08-01

Tumor-associated macrophages constitute a major component of the stroma of solid tumors, encompassing distinct subpopulations with different characteristics and functions. We aimed to identify M2-oriented tumor-supporting macrophages within the tumor microenvironment as indicators of cancer progression and prognosis, using PET imaging. This can be realized by designing (18)F-labeled camelid single-domain antibody fragments (sdAbs) specifically targeting the macrophage mannose receptor (MMR), which has been identified as an important biomarker on this cell population. Cross-reactive anti-MMR sdAbs were generated after immunization of an alpaca with the extracellular domains of both human and mouse MMR. The lead binder was chosen on the basis of comparisons of binding affinity and in vivo pharmacokinetics. The PET tracer (18)F-fluorobenzoate (FB)-anti-MMR sdAb was developed using the prosthetic group N-succinimidyl-4-(18)F-fluorobenzoate ((18)F-SFB), and its biodistribution, tumor-targeting potential, and specificity in terms of macrophage and MMR targeting were evaluated in mouse tumor models. Four sdAbs were selected after affinity screening, but only 2 were found to be cross-reactive for human and mouse MMR. The lead anti-MMR 3.49 sdAb, bearing an affinity of 12 and 1.8 nM for mouse and human MMR, respectively, was chosen for its favorable in vivo biodistribution profile and tumor-targeting capacity. (18)F-FB-anti-MMR 3.49 sdAb was synthesized with a 5%-10% radiochemical yield using an automated and optimized protocol. In vivo biodistribution analyses showed fast clearance via the kidneys and retention in MMR-expressing organs and tumor. The kidney retention of the fluorinated sdAb was 20-fold lower than a (99m)Tc-labeled counterpart. Compared with MMR- and C-C chemokine receptor 2-deficient mice, significantly higher uptake was observed in tumors grown in wild-type mice, demonstrating the specificity of the (18)F tracer for MMR and macrophages, respectively. Anti

Climate change and its effect on world food

International Nuclear Information System (INIS)

Roberts, W.O.

1974-01-01

In February of 1972 earth-orbiting artificial satellites revealed the existence of a greatly increased area of the snow and ice cover of the north polar cap as compared to all previous years of space age observations. Some scientists believe that this may have presaged the onset of the dramatic climate anomalies of 1972 that brought far-reaching adversities to the world's peoples. Moreover, there is mounting evidence that the bad climate of 1972 may be the forerunner of a long series of less favorable agricultural crop years that lie ahead for most world societies. Thus widespread food shortages threaten just at the same time that world populations are growing to new highs. Indeed, less favorable climate may be the new global norm. The Earth may have entered a new 'little ice age'. Perhaps this future period will not be so extreme as that around 1700 AD, but it seems likely, at least, to be a cooler period resembling the hemispheric climatic regimes of the period from 1880-1920. (author)

Design of a humanized anti vascular endothelial growth factor nanobody and evaluation of its in vitro function

OpenAIRE

Fatemeh Kazemi-Lomedasht; serge muyldermans; Mahdi Habibi-Anbouhi; Mahdi Behdani

2018-01-01

Objective(s): Nanobodies, the single domain antigen binding fragments of heavy chain-only antibodies occurring naturally in camelid sera, are the smallest intact antigen binding entities. Their minimal size assists in reaching otherwise largely inaccessible regions of antigens. However, their camelid origin raises a possible concern of immunogenicity when used for human therapy. Humanization is a promising approach to overcome the problem.   Materials and Methods: Here, we designed a humanize...

Belgium’s position in world trade

OpenAIRE

V. Baugnet; K. Burggraeve; L. Dresse; Ch. Piette; B. Vuidar

2010-01-01

The objective of the article is to give a general overview of the position that Belgium occupies in the world trade stakes and its ability to adjust in response to changes in the international environment. Over the last two decades, world trade has expanded considerably, buoyed up by the rapid growth of new economic centres, the advanced economies generally having seen a drop in their market share. However, the growth in Belgium’s exports has lagged behind the average for twelve European coun...

Post-Colonial Africa and the World Economy: The Long Waves of Uneven Development

Directory of Open Access Journals (Sweden)

Fouad Makki

2015-08-01

Full Text Available The aim of this article is to examine the interactive dynamics of "Africa" and the "world economy" over the past half century. By relating the overarching developmental trajectory of the continent to the long-wave rhythms of the world economy, the article identifies three relatively articulated periods in the political economy of postcolonial Africa. The first, from circa 1960 to the late 1970s, was a period of state-led developmentalism enabled by the long postwar boom in the world economy and the embedded liberalism of the Bretton Woods system. A second period from circa 1980 to the turn of the new century was conditioned by the long downturn in the world-economy and a neo-li beral regime of accumulation that sought to re-structure and re-integrate Africa into a deregulated world market. The turn of the new millennium constitutes a new period in which neither the deep structural springs of the long downturn nor the neo-liberal project as such have been overcome; but their impact on Africa has been relativized by the emergence of East Asia as the new center of accumulation in the world economy. The resulting de-synchronization of the long-wave rhythms of the world economy has permitted a modest economic expansion in Africa within a largely extractive regime of accumulation and a wave of new enclosures that are profoundly reconstituting the social universe of Africa's primary producers.

Technical Communication--The Need and the Demand of Global World

Science.gov (United States)

Patel, Dipika S.

2013-01-01

The present world is known as Hi-tech world as it is driven by technology. It is the vehicle to get access with this modernized world. However, due to continuous changes taking place in the field of technology, people keep looking for new developments for improving the quality of teaching and learning methodologies. In the fast developing 21st…

The new urban world: Challenges and policy

NARCIS (Netherlands)

Kourtit, K.; Nijkamp, P.; Reid, N.

2014-01-01

As the process of urbanization continues unabated new and emerging socio-economic trends will present both new challenges and opportunities for not only the residents of urban areas but also for those who govern them, plan for them, and research them. In this introductory article we provide a

NetSuite OneWorld Implementation 2011 R2

CERN Document Server

Foydel, Thomas

2011-01-01

This book is a focused, step-by step tutorial that shows you how to successfully implement NetSuite OneWorld into your organization. It is written in an easy-to-read style, with a strong emphasis on real-world, practical examples with step-by-step explanations. The book focuses on NetSuite OneWorld 2011 R1. If you are an application administrator, business analyst, project team member or business process owner who wants to implement NetSuite OneWorld into your organization, then this book is for you. This book might also be useful if you are a business manager considering a new system for your

A taxonomic revision of Liogenys occurring in Brazil with an interactive key and remarks on New World Diplotaxini (Coleoptera, Melolonthidae)

Science.gov (United States)

Cherman, Mariana Alejandra; Mise, Kleber Makoto; Morón†, Miguel Angel; Vaz-de-Mello, Fernando Z.; de Almeida, Lúcia Massutti

2017-01-01

Abstract Liogenys Guérin-Méneville, 1831 is the major genus of Neotropical Diplotaxini, with 78 species distributed from Panama to southern Argentina and Chile, except for Ecuador. Due to the large numbers of both described and undescribed species, as well as its agricultural importance, mainly of those in Brazil, Liogenys was redefined and redescribed. Nine new species are described: L. cavifrons Cherman, sp. n., L. femella Cherman, sp. n., L. piauiensis Cherman, sp. n., L. rotundicollis Cherman, sp. n., L. pseudosanctaecrucis Cherman, sp. n., L. grossii Cherman, sp. n., L. pseudospiniventris Cherman, sp. n., L. sulcoventris Cherman, sp. n., and L. freyi Cherman, sp. n. All the new species are Brazilian, except for the last one, which is Argentinian. Twenty-three Brazilian species are redescribed and illustrated. Five new synonyms are proposed, and 19 lectotypes are designated. New geographical distribution records for 19 species are presented, as well as a key to New World Diplotaxini and Brazilian species of Liogenys. PMID:29200927

French in Culinary World

Directory of Open Access Journals (Sweden)

Rila Hilma

2011-10-01

Full Text Available More than million foods have been made by people from all over the world in the latest years. People now try to create new cooks and make some creativity on it. Then, cooking which the field is culinary has become an art because it needs an artistic value to decorate the food, a good taste and proper technique in processing delicious food in order to make it a masterpiece. French culinary is as famous as the Eiffel tower in the heart of the country, Paris. Most of fine dining international restaurants apply the French menu and cooking. This article presents an overview about the French element in culinary world; starts from its history, kitchen organization, French menu spelling, and French cooking vocabulary. The discussion proceeds library research to compile the data. Later, the art of culinary is interesting to be learned because it contains the classical history of world civilization, in this case French civilization. The issue of cooking trend “nouvelle cuisine” was a masterpiece of one of the greatest chef in his time, Escoffier. French culinary is widely well-known in all over the world because of innovation, creativity, and proud. Those are spirits that we must learn.   

World energy outlook. Energy efficiency policies in the World: what works and what does not

International Nuclear Information System (INIS)

2013-01-01

Long considered simply as an 'option' in the OECD countries, energy efficiency is spreading, with notable progress in all major regions of the world. The experience gained by the OECD countries benefits so-called emerging countries, as demonstrated by the study of energy efficiency in the world conducted by ADEME for the World Energy Council. A relative international consensus is emerging. It sees energy efficiency as a beneficial strategy for each stakeholder: reducing dependence on energy imports, reducing emissions of greenhouse gas emissions related to energy, preserving the competitiveness of companies and household purchasing power, etc. This good news appears to be an illusion, however, with a general decrease in energy efficiency over the recent years. Regional disparities remain and new solutions must be found to take the reality of each country into account and thus move to the next level

Faunal record identifies Bering isthmus conditions as constraint to end-Pleistocene migration to the New World

Science.gov (United States)

Meiri, Meirav; Lister, Adrian M.; Collins, Matthew J.; Tuross, Noreen; Goebel, Ted; Blockley, Simon; Zazula, Grant D.; van Doorn, Nienke; Dale Guthrie, R.; Boeskorov, Gennady G.; Baryshnikov, Gennady F.; Sher, Andrei; Barnes, Ian

2014-01-01

Human colonization of the New World is generally believed to have entailed migrations from Siberia across the Bering isthmus. However, the limited archaeological record of these migrations means that details of the timing, cause and rate remain cryptic. Here, we have used a combination of ancient DNA, 14C dating, hydrogen and oxygen isotopes, and collagen sequencing to explore the colonization history of one of the few other large mammals to have successfully migrated into the Americas at this time: the North American elk (Cervus elaphus canadensis), also known as wapiti. We identify a long-term occupation of northeast Siberia, far beyond the species’s current Old World distribution. Migration into North America occurred at the end of the last glaciation, while the northeast Siberian source population became extinct only within the last 500 years. This finding is congruent with a similar proposed delay in human colonization, inferred from modern human mitochondrial DNA, and suggestions that the Bering isthmus was not traversable during parts of the Late Pleistocene. Our data imply a fundamental constraint in crossing Beringia, placing limits on the age and mode of human settlement in the Americas, and further establish the utility of ancient DNA in palaeontological investigations of species histories. PMID:24335981

World NGL markets continue rapid expansion

International Nuclear Information System (INIS)

Otto, K.; Gist, R.; Whitley, C.; Haun, R.

1998-01-01

The international LPG industry has expanded rapidly during the 1990s and undergone significant changes. LPG consumption has expanded at nearly twice the rate of world petroleum demand. In particular, LPG use in residential and commercial markets has more than doubled in many developing countries. Markets for LPG and other petroleum products have been opened in many countries, accelerating demand growth and creating investment opportunities in all downstream segments. This has led to an overall strengthening of global LPG pricing and the development of many new export gas-processing projects. The paper discusses world LPG demand in residential and commercial markets and in petrochemicals, world LPG supply, regional increases, international trade, the US situation in natural gas, NGL supply, and NGL demand

What Children Should Know about Technology and the Virtual World

Science.gov (United States)

Zhao, Yong

2010-01-01

The dominant view of technology so far has been that it is a tool to help improve the teaching of traditional subjects--knowledge mostly about the local and physical world. But technology has created a new realm: the virtual world. It may not be physical or tangible, but the virtual world is indisputable and has a significant economy. If one…

The body hunters: testing new drugs on the world's poorest patients

National Research Council Canada - National Science Library

Shah, Sonia

2006-01-01

... of the world's most profitable trade: the pharmaceutical industry. Where a proposed book seemed to have merit, and was not weighed down with mountains of medical jargon, I passed the word to liter...

The oil world war

International Nuclear Information System (INIS)

Lafargue, F.

2008-01-01

Since the beginning of the 21. century, a war has started between the USA, China and India. The USA, first oil consuming and importing country in the world, has now to take into account the increasing energy consumption of China and India. China is now, just behind Japan, the third oil importing country and India ranked number seven. From the Gulf of Guinea to the Arabic peninsula, from the Orenoque basin to the Caspian sea banks, Washington, Beijing and New Delhi covet the same oil fields. This rivalry exacerbates the political tensions in many regions of the Earth and already provokes a latent food crisis. This black gold war is changing the World's face and should provoke serious armed conflicts. (J.S.)

New World hantaviruses activate IFNlambda production in type I IFN-deficient vero E6 cells.

Directory of Open Access Journals (Sweden)

Joseph Prescott

Full Text Available Hantaviruses indigenous to the New World are the etiologic agents of hantavirus cardiopulmonary syndrome (HCPS. These viruses induce a strong interferon-stimulated gene (ISG response in human endothelial cells. African green monkey-derived Vero E6 cells are used to propagate hantaviruses as well as many other viruses. The utility of the Vero E6 cell line for virus production is thought to owe to their lack of genes encoding type I interferons (IFN, rendering them unable to mount an efficient innate immune response to virus infection. Interferon lambda, a more recently characterized type III IFN, is transcriptionally controlled much like the type I IFNs, and activates the innate immune system in a similar manner.We show that Vero E6 cells respond to hantavirus infection by secreting abundant IFNlambda. Three New World hantaviruses were similarly able to induce IFNlambda expression in this cell line. The IFNlambda contained within virus preparations generated with Vero E6 cells independently activates ISGs when used to infect several non-endothelial cell lines, whereas innate immune responses by endothelial cells are specifically due to viral infection. We show further that Sin Nombre virus replicates to high titer in human hepatoma cells (Huh7 without inducing ISGs.Herein we report that Vero E6 cells respond to viral infection with a highly active antiviral response, including secretion of abundant IFNlambda. This cytokine is biologically active, and when contained within viral preparations and presented to human epithelioid cell lines, results in the robust activation of innate immune responses. We also show that both Huh7 and A549 cell lines do not respond to hantavirus infection, confirming that the cytoplasmic RNA helicase pathways possessed by these cells are not involved in hantavirus recognition. We demonstrate that Vero E6 actively respond to virus infection and inhibiting IFNlambda production in these cells might increase their utility

Collage technique may provide new perspectives for Alzheimer patients by exploring messages from their inner world.

Science.gov (United States)

Meguro, Mitsue; Ishizaki, Junichi; Meguro, Kenichi

2009-01-01

Although the collage art technique has been introduced as a psychotherapeutic method, it has not been fully applied in dementia. To analyze characteristics of the collage articles produced by patients with Alzheimer's disease (AD). Twenty AD patients were asked to select and place several clippings as they wished. The MMSE was used for cognitive assessments. Simplification and poor organization in their articles were found. The themes of one patient were found to change according to behavior. We discussed the images of the articles, especially spiritual images in the early stage and family images in the later stage. We concluded that the collage technique could provide new perspectives for dementia patients by exploring messages from their inner world.

The influence of new world species on the botany of the 16th century

Directory of Open Access Journals (Sweden)

Ubrizsy Savoia, Andrea

1996-12-01

Full Text Available This paper is about how some New World species, not as widespread as tomato, tobacco, etc. were introduced in the botanical European knowledge, with special reference to Ulisse Aldrovandi (1522-1605. His herbal, his inconographic collections and manuscripts containing lists of seeds, woods and other matrials, are conserved in his Museum and grown in the Botanical Garden of Bologna.

El presente trabajo analiza cómo algunas especies botánicas del Nuevo mundo, no tan difundidas como el tomate, el tabaco, etc., formaron parte del conocimiento botánico europeo, haciendo especial referencia a la de obra de Ulisse Aldrovandi (1522-1605. Su herbario, sus colecciones iconográficas y manuscritos que contienen listas de semillas, maderas y otros materiales, se conservan en su Museo y algunas de las especies crecen en el Jardín Botánico de Bolonia.

Brave new world: Myth and migration in recent Asian-Australian picture books