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Sample records for cam interlock system

  1. Availability Analysis of the Ventilation Stack CAM Interlock System

    CERN Document Server

    Young, J

    2000-01-01

    Ventilation Stack Continuous Air Monitor (CAM) Interlock System failure modes, failure frequencies, and system availability have been evaluated for the RPP. The evaluation concludes that CAM availability is as high as assumed in the safety analysis and that the current routine system surveillance is adequate to maintain this availability credited in the safety analysis, nor is such an arrangement predicted to significantly improve system availability.

  2. Availability Analysis of the Ventilation Stack CAM Interlock System

    International Nuclear Information System (INIS)

    YOUNG, J.

    2000-01-01

    Ventilation Stack Continuous Air Monitor (CAM) Interlock System failure modes, failure frequencies and system availability have been evaluated for the RPP. The evaluation concludes that CAM availability is as high as assumed in the safety analysis and that the current routine system surveillance is adequate to maintain this availability. Further, requiring an alarm to actuate upon CAM failure is not necessary to maintain the availability credited in the safety analysis, nor is such an arrangement predicted to significantly improve system availability. However, if CAM failures were only detected by the 92-day functional tests required in the Authorization Basis (AB), CAM availability would be much less than that credited in the safety analysis. Therefore it is recommended that the current surveillance practice of daily simple system checks, 30-day source checks and 92-day functional tests be continued in order to maintain CAM availability

  3. Operability of the Ventilation Continuous Air Monitor (CAM) Interlock Analysis of Proposed Upgrade to the 241AW Farm Primary Exhauster CAM System

    International Nuclear Information System (INIS)

    GUSTAVSON, R.D.

    2002-01-01

    The Tank Farms Final Safety Analysis (FSAR) assumes that a ventilation stack Continuous Air Monitor (CAM) interlock system detects high radiation in the exhaust stream and shuts off the associated ventilation system within 10 minutes of a High-Efficiency Particulate Air (HEPA) filter system failure (CHG, 2002). Previous analysis of the as-built CAM system on the AW Farm Primary Exhauster (stack 296-A-27) showed that this system potentially required significantly longer than 10 minutes to detect a HEPA filter failure and initiate shutdown of the ventilation system (Short, 2002). The purpose of this report is to determine the CAM interlock system response time for a proposed upgrade of the 296-A-27 CAM system. The approach to be used in this analysis is essentially the same as used in RPP-10799, Rev. 0 (Short, 2002), which is to conservatively estimate the time required by the proposed upgraded CAM sampling/monitoring system to detect a FSAR-defined HEPA filter failure and automatically shutdown the exhaust fan. For the HEPA filter failure over-temperature accident scenario in the FSAR, the upgraded CAM system on the AW Farm Primary Exhauster will require significantly less than 10 minutes to detect a HEPA filter failure, actuate the CAM Interlock, and shutdown the exhauster fan. Therefore, the analyzed system is adequate to meet the operability requirements specified in the FSAR and the Tank Farms Technical Safety Requirements (CHG, 2001; CHG, 2002)

  4. Modelling Railway Interlocking Systems

    DEFF Research Database (Denmark)

    Lindegaard, Morten Peter; Viuf, P.; Haxthausen, Anne Elisabeth

    2000-01-01

    In this report we present a model of interlocking systems, and describe how the model may be validated by simulation. Station topologies are modelled by graphs in which the nodes denote track segments, and the edges denote connectivity for train traÆc. Points and signals are modelled by annotatio...

  5. Interlocked systems in nanomedicine.

    Science.gov (United States)

    Ornelas-Megiatto, Catia; Becher, Tiago B; Megiatto, Jackson D

    2015-01-01

    The concept of Nanomedicine emerged along with the new millennium, and it is expected to provide solutions to some of modern medicine's unsolved problems. Nanomedicine offers new hopes in several critical areas such as cancer treatment, viral and bacterial infections, medical imaging, tissue regeneration, and theranostics. To explore all these applications, a wide variety of nanomaterials have been developed which include liposomes, dendrimers, nanohydrogels and polymeric, metallic and inorganic nanoparticles. Recently, interlocked systems, namely rotaxanes and catenanes, have been incorporated into some of these chemical platforms in an attempt to improve their performance. This review focus on the nanomedicine applications of nanomaterials containing interlocked structures. The introduction gives an overview on the significance of interdisciplinary science in the progress of the nanomedicine field, and it explains the evolution of interlocked molecules until their application in nanomedicine. The following sections are organized by the type of interlocked structure, and it comprises details of the in vitro and/or in vivo experiments involving each material: rotaxanes as imaging agents, rotaxanes as cytotoxic agents, rotaxanes as peptide transporters, mechanized silica nanoparticles as stimuli responsive drug delivery systems, and polyrotaxanes as drug and gene delivery systems.

  6. Modelling and Verification of Relay Interlocking Systems

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth; Bliguet, Marie Le; Kjær, Andreas

    2010-01-01

    This paper describes how relay interlocking systems as used by the Danish railways can be formally modelled and verified. Such systems are documented by circuit diagrams describing their static layout. It is explained how to derive a state transition system model for the dynamic behaviour of a re...

  7. Comparing formal verification approaches of interlocking systems

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth; Nguyen, Hoang Nga; Roggenbach, Markus

    2016-01-01

    The verification of railway interlocking systems is a challenging task, and therefore several research groups have suggested to improve this task by using formal methods, but they use different modelling and verification approaches. To advance this research, there is a need to compare...... these approaches. As a first step towards this, in this paper we suggest a way to compare different formal approaches for verifying designs of route-based interlocking systems and we demonstrate it on modelling and verification approaches developed within the research groups at DTU/Bremen and at Surrey...

  8. Application software for new BEPC interlock system

    International Nuclear Information System (INIS)

    Tang Shuming; Na Xiangyin; Chen Jiansong; Yu Yulan

    1997-01-01

    New BEPC (Beijing electron Positron collider) interlock system has been built in order to improve the reliability of personnel safety and interlock functions. Moreover, the system updates BEPC operation message once every 6 seconds, which are displayed on TV screens at the major entrances. Since March of 1996, new BEPC interlock system has been operating reliably. The hardware of the system is based on Programmable Logic Controllers (PLC). A multimedia IBM/PC-586 as the host computer of the PLCs, monitors the PLC system via serial port COM2. The PC communicates with the central computer VAX-4500 of BEPC control system and gets operating massage of the accelerator through serial port COM3. The application software on the host computer has been developed. Visual C++ for MS-Windows 3.2 TM is selected as the work bench. It provides nice tools for building programs, such as APP STUDIO, CLASS WIZARD, APP WIZARD and debugger tool. The author describes the design idea and the structure of the application software. Error tolerance is taken into consideration. The author also presents a small database and its data structure for the application

  9. The SDUV-FEL vacuum interlock system

    International Nuclear Information System (INIS)

    Qi Binchuan; Zhu Haijun; Ding Jiangguo

    2011-01-01

    Shanghai Deep Ultraviolet Free Electron Laser (SDUV-FEL) test facility is an integrated multi-purpose test bed for FEL principles. In this paper, we focus on the development of an interlock system for SDUV-FEL vacuum protection. Hardware and software of the system implementations are introduced. A distributed control system composed of a PLC, an embedded computer and consoles based on EPICS toolkit is described in details. The system has been used for cascaded HGHG FEL experiment. Stability and reliability has been demonstrated. (authors)

  10. Formal modelling and verification of interlocking systems featuring sequential release

    DEFF Research Database (Denmark)

    Vu, Linh Hong; Haxthausen, Anne Elisabeth; Peleska, Jan

    2017-01-01

    In this article, we present a method and an associated toolchain for the formal verification of the new Danish railway interlocking systems that are compatible with the European Train Control System (ETCS) Level 2. We have made a generic and reconfigurable model of the system behaviour and generic...... safety properties. This model accommodates sequential release - a feature in the new Danish interlocking systems. To verify the safety of an interlocking system, first a domain-specific description of interlocking configuration data is constructed and validated. Then the generic model and safety...

  11. Formal Verification of the Danish Railway Interlocking Systems

    DEFF Research Database (Denmark)

    Vu, Linh Hong; Haxthausen, Anne Elisabeth; Peleska, Jan

    2014-01-01

    in the new Danish interlocking systems. Instantiating the generic model with interlocking configuration data results in a concrete model and high-level safety properties. Using bounded model checking and inductive reasoning, we are able to verify safety properties for model instances corresponding to railway...

  12. Applied Bounded Model Checking for Interlocking System Designs

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth; Peleska, Jan; Pinger, Ralf

    2014-01-01

    In this paper the verification and validation of interlocking systems is investigated. Reviewing both geographical and route-related interlocking, the verification objectives can be structured from a perspective of computer science into (1) verification of static semantics, and (2) verification...

  13. Compositional Verification of Multi-Station Interlocking Systems

    DEFF Research Database (Denmark)

    Macedo, Hugo Daniel dos Santos; Fantechi, Alessandro; Haxthausen, Anne Elisabeth

    2016-01-01

    Because interlocking systems are highly safety-critical complex systems, their automated safety verification is an active research topic investigated by several groups, employing verification techniques to produce important cost and time savings in their certification. However, such systems also...

  14. A Domain-Specific Language for Railway Interlocking Systems

    DEFF Research Database (Denmark)

    Vu, Linh Hong; Haxthausen, Anne Elisabeth; Peleska, Jan

    2014-01-01

    This paper presents a domain-specific language (DSL) for describing route-based interlocking systems which are compatible with European Train Control System ETCS Level 2. The abstract syntax and static semantics of the language are formally defined using the RAISE Specification Language (RSL......). Furthermore, the paper describes an interlocking table generator (ITG) that generates automatically a well-formed interlocking table from a well-formed railway network layout. Experiments with the DSL and ITG using the RAISE tools and the C++ implementation show that the use of the DSL and ITG can increase...

  15. Adaptive mechanical properties of topologically interlocking material systems

    International Nuclear Information System (INIS)

    Khandelwal, S; Siegmund, T; Cipra, R J; Bolton, J S

    2015-01-01

    Topologically interlocked material systems are two-dimensional granular crystals created as ordered and adhesion-less assemblies of unit elements of the shape of platonic solids. The assembly resists transverse forces due to the interlocking geometric arrangement of the unit elements. Topologically interlocked material systems yet require an external constraint to provide resistance under the action of external load. Past work considered fixed and passive constraints only. The objective of the present study is to consider active and adaptive external constraints with the goal to achieve variable stiffness and energy absorption characteristics of the topologically interlocked material system through an active control of the in-plane constraint conditions. Experiments and corresponding model analysis are used to demonstrate control of system stiffness over a wide range, including negative stiffness, and energy absorption characteristics. The adaptive characteristics of the topologically interlocked material system are shown to solve conflicting requirements of simultaneously providing energy absorption while keeping loads controlled. Potential applications can be envisioned in smart structure enhanced response characteristics as desired in shock absorption, protective packaging and catching mechanisms. (paper)

  16. Design of a dependable Interlock System for linear colliders

    CERN Document Server

    Nouvel, Patrice

    For high energy accelerators, the interlock system is a key part of the machine protection. The interlock principle is to inhibit the beam either on failure of critical equipment and/or on low beam quality evaluation. The dependability of such a system is the most critical parameter. This thesis presents the design of an dependable interlock system for linear collider with an application to the CLIC (Compact Linear Collider) project. This design process is based on the IEEE 1220 standard and is is divided in four steps. First, the specifications are established, with a focus on the dependability, more precisely the reliability and the availability of the system. The second step is the design proposal based on a functional analysis, the CLIC and interfaced systems architecture. Third, the feasibility study is performed, applying the concepts in an accelerator facility. Finally, the last step is the hardware verification. Its aim is to prove that the proposed design is able to reach the requirements.

  17. Applied Bounded Model Checking for Interlocking System Designs

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth; Peleska, Jan; Pinger, Ralf

    2013-01-01

    In this article the verification and validation of interlocking systems is investigated. Reviewing both geographical and route-related interlocking, the verification objectives can be structured from a perspective of computer science into (1) verification of static semantics, and (2) verification...... of behavioural (operational) semantics. The former checks that the plant model – that is, the software components reflecting the physical components of the interlocking system – has been set up in an adequate way. The latter investigates trains moving through the network, with the objective to uncover potential...... safety violations. From a formal methods perspective, these verification objectives can be approached by theorem proving, global, or bounded model checking. This article explains the techniques for application of bounded model checking techniques, and discusses their advantages in comparison...

  18. A Domain-Specific Language for Railway Interlocking Systems

    DEFF Research Database (Denmark)

    Vu, Linh Hong; Haxthausen, Anne Elisabeth; Peleska, Jan

    2014-01-01

    This paper presents a domain-specific language (DSL) for describing route-based interlocking systems which are compatible with European Train Control System ETCS Level 2. The abstract syntax and static semantics of the language are formally defined using the RAISE Specification Language (RSL...

  19. Automatic Verification of Railway Interlocking Systems: A Case Study

    DEFF Research Database (Denmark)

    Petersen, Jakob Lyng

    1998-01-01

    This paper presents experiences in applying formal verification to a large industrial piece of software. The are of application is railway interlocking systems. We try to prove requirements of the program controlling the Swedish railway Station Alingsås by using the decision procedure which is ba...

  20. Interlock system for the COMPASS tokamak

    Czech Academy of Sciences Publication Activity Database

    Hron, Martin; Sova, J.; Šíba, J.; Kovář, J.; Adámek, Jiří; Pánek, Radomír; Havlíček, Josef; Písačka, Jan; Mlynář, Jan; Stöckel, Jan

    2010-01-01

    Roč. 85, 3-4 (2010), s. 505-508 ISSN 0920-3796. [IAEA Technical Meeting on Control, Data Acquisition and Remote Participation for Fusion Research/7th./. Aix – en – Provence, 15.06.2009-19.06.2009] R&D Projects: GA MŠk 7G09042; GA ČR GD202/08/H057 Institutional research plan: CEZ:AV0Z20430508 Keywords : Tokamak operation * Interlock * Personnel safety Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.143, year: 2010 http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6V3C-5003BXW-1&_user=6542793&_coverDate=07%2F31%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000070123&_version=1&_urlVersion=0&_userid=6542793&md5=ef5794d05cc6530a905d1de43aa0ac6a&searchtype=a

  1. Central system of Interlock of ITER, high integrity architecture

    International Nuclear Information System (INIS)

    Prieto, I.; Martinez, G.; Lopez, C.

    2014-01-01

    The CIS (Central Interlock System), along with the CODAC system and CSS (Central Safety System), form the central I and C systems of ITER. The CIS is responsible for implementing the core functions of protection (Central Interlock Functions) through different systems of plant (Plant Systems) within the overall strategy of investment protection for ITER. IBERDROLA supports engineering to define and develop the control architecture of CIS according to the stringent requirements of integrity, availability and response time. For functions with response times of the order of half a second is selected PLC High availability of industrial range. However, due to the nature of the machine itself, certain functions must be able to act under the millisecond, so it has had to develop a solution based on FPGA (Field Programmable Gate Array) capable of meeting the requirements architecture. In this article CIS architecture is described, as well as the process for the development and validation of the selected platforms. (Author)

  2. Modular safety interlock system for high energy physics experiments

    International Nuclear Information System (INIS)

    Kieffer, J.; Golceff, B.V.

    1980-10-01

    A frequent problem in electronics systems for high energy physics experiments is to provide protection for personnel and equipment. Interlock systems are typically designed as an afterthought and as a result, the working environment around complex experiments with many independent high voltages or hazardous gas subsystems, and many different kinds of people involved, can be particularly dangerous. A set of modular hardware has been designed which makes possible a standardized, intergrated, hierarchical system's approach and which can be easily tailored to custom requirements

  3. Design of modified safety interlock system for pelletron accelerator

    International Nuclear Information System (INIS)

    Yadav, M.L.; Lokare, R.N.; Matkar, U.V.; Ekambaram, M.; Gudekar, P.V.; Vishwakarma, Ramlal S.; Kulkarni, S.G.; Gore, J.A.; Gupta, A.K.; Datar, V.M.

    2013-01-01

    The BARC-TIFR Pelletron Accelerator Facility has been operational for last twenty four years progressively with increased efficiency, delivering energetic light and heavy ions at medium energy. The process of beam acceleration makes the accelerator tower and beam hall radiation prone areas. A modified Interlock system for Pelletron Accelerator has been designed and developed to ensure radiation safety of the personnel working in the accelerator premises. Radiation levels from monitors, status of search and secure switches and entry doors of the accelerator tower, are inputs to the interlock system. The system triggers if radiation level exceeds the set value or status of any search and secure switches and entry doors across the tower are changed, thus stopping the beam at ion source level. This system also incorporates new features like-audio visual alarm pertaining to each location. (author)

  4. Neutral beam interlock system on TFTR using infrared pyrometry

    International Nuclear Information System (INIS)

    Medley, S.S.; Kugel, H.W.; Kozub, T.A.; Lowrance, J.L.; Mastrocola, V.; Renda, G.; Young, K.M.

    1986-01-01

    Although the region of the Tokamak Fusion Test Reactor (TFTR) vacuum vessel wall which is susceptible to damage by neutral beam strike is armored with a mosaic of TiC-clad POCO graphite tiles, at power deposition levels above 2.5 kW/cm 2 the armor surface temperature exceeds 1200 0 C within 250 ms, and itself becomes susceptible to damage. In order to protect the wall armor, a neutral beam interlock system based on infrared pyrometry measurement of the armor surface temperature was installed on TFTR. For each beamline, a three-fiber-optic telescope views three areas of --30 cm diameter centered on the armor hot spots for the three ion sources. Each signal is fiber-optic coupled to a remote 900-nm pyrometer which feeds analog signals to the neutral beam interrupt circuits. The pyrometer interlock system is designed to interrupt each of the 12 ion sources independently within 10 ms of the temperature exceeding a threshold which can be set in the range of 500--2300 0 C. A description of the pyrometer interlock system and its performance will be presented

  5. Verifying therapy safety interlock system with spin

    CSIR Research Space (South Africa)

    Seotsanyana, M

    2009-11-01

    Full Text Available System component represents TCS systems and electronic units. It connects to the TSB and TCS lines by sending a message register to the tlabsMediator component and unconnect from these lines through an unregister message. It also changes lines to either true... or false and emits two different messages (update and notify) to the tlabMediator component. The sysUtility component takes care of administrative work for the tlabSystem components, including receiving the display messages from other components. The tlabMediator...

  6. Model Checking Geographically Distributed Interlocking Systems Using UMC

    DEFF Research Database (Denmark)

    Fantechi, Alessandro; Haxthausen, Anne Elisabeth; Nielsen, Michel Bøje Randahl

    2017-01-01

    The current trend of distributing computations over a network is here, as a novelty, applied to a safety critical system, namely a railway interlocking system. We show how the challenge of guaranteeing safety of the distributed application has been attacked by formally specifying and model checking...... the relevant distributed protocols. By doing that we obey the safety guidelines of the railway signalling domain, that require formal methods to support the certification of such products. We also show how formal modelling can help designing alternative distributed solutions, while maintaining adherence...

  7. Indus-2 machine safety interlock system - from design to commissioning

    International Nuclear Information System (INIS)

    Gothwal, Pankaj; Gupta, A.M.; Merh, B.; Fatnani, P.; Kumar, S.; Vaishnav, H.; Satheesan, T.V.

    2009-01-01

    INDUS-2 is a 2.5 GeV, 300 mA electron storage ring in operation at RRCAT, Indore. It is a one of its kind national facility with plans for 27 user beam lines from bending magnets. Any such large facility requires sufficient measures of machine safety besides occupational radiation safety during normal course of operation. In fact, machine safety is a major concern as any serious fault can cause expensive and extensive damage to machine components like magnets, vacuum chambers, vacuum valves etc. resulting in possibly long periods of machine shutdown. The machine has to clear many pre-checks to come to states of operation and certain conditions have to be maintained for operating it safely. The Machine Safety Interlock System (MSIS) must fulfil the normal requirements of a safety critical system. In the accelerator environment, such system must be easily configurable and expandable also. Therefore an intelligent computer based system has been developed and deployed. The INDUS-2 MSIS takes inputs from cooling water switches of photon absorbers and magnets, magnet coil temperatures, DCCT core temperature, vacuum sector valve status, door interlocks and search and scram system, integrated temperature status from vacuum chambers etc. The machine condition inputs to trip outputs relations are defined with equations. The paper presents the design basis, the system implementation details, performance issues and experiences. (author)

  8. Formal Development of a Tool for Automated Modelling and Verification of Relay Interlocking Systems

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth; Kjær, Andreas A.; Le Bliguet, Marie

    2011-01-01

    This paper describes a tool for formal modelling relay interlocking systems and explains how it has been stepwise, formally developed using the RAISE method. The developed tool takes the circuit diagrams of a relay interlocking system as input and gives as result a state transition system modelling...

  9. CAM: A Collaborative Object Memory System

    NARCIS (Netherlands)

    Vyas, Dhaval; Nijholt, Antinus; Kröner, Alexander

    2010-01-01

    Physical design objects such as sketches, drawings, collages, storyboards and models play an important role in supporting communication and coordination in design studios. CAM (Cooperative Artefact Memory) is a mobile-tagging based messaging system that allows designers to collaboratively store

  10. Compositional Model Checking of Interlocking Systems for Lines with Multiple Stations

    DEFF Research Database (Denmark)

    Macedo, Hugo Daniel dos Santos; Fantechi, Alessandro; Haxthausen, Anne Elisabeth

    2017-01-01

    In the railway domain safety is guaranteed by an interlocking system which translates operational decisions into commands leading to field operations. Such a system is safety critical and demands thorough formal verification during its development process. Within this context, our work has focused...... on the extension of a compositional model checking approach to formally verify interlocking system models for lines with multiple stations. The idea of the approach is to decompose a model of the interlocking system by applying cuts at the network modelling level. The paper introduces an alternative cut (the...... linear cut) to a previously proposed cut (border cut). Powered with the linear cut, the model checking approach is then applied to the verification of an interlocking system controlling a real-world multiple station line....

  11. Combat Agility Management System (CAMS)

    Science.gov (United States)

    Skow, Andrew; Porada, William

    1994-01-01

    The proper management of energy becomes a complex task in fighter aircraft which have high angle of attack (AOA) capability. Maneuvers at high AOA are accompanied by high bleed rates (velocity decrease), a characteristic that is usually undesirable in a typical combat arena. Eidetics has developed under NASA SBIR Phase 1 and NAVAIR SBIR Phase 2 contracts a system which allows a pilot to more easily and effectively manage the trade-off of energy (airspeed or altitude) for turn rate while not imposing hard limits on the high AOA nose pointing capability that can be so important in certain air combat maneuver situations. This has been accomplished by incorporating a two-stage angle of attack limiter into the flight control laws. The first stage sets a limit on AOA to achieve a limit on the maximum bleed rate (selectable) by limiting AOA to values which are dependent on the aircraft attitude and dynamic pressure (or flight path, velocity, and altitude). The second stage sets an AOA limit near the AOA for C(sub l max). One of the principal benefits of such a system is that it enables a low-experience pilot to become much more proficient at managing his energy. The Phase 2 simulation work is complete, and an exploratory flight test on the F-18 HARV is planned for the Fall of 1994 to demonstrate/validate the concept.

  12. NSTX Protection And Interlock Systems For Coil And Powers Supply Systems

    International Nuclear Information System (INIS)

    Zhao, X.; Ramakrishnan, S.; Lawson, J.; Neumeyer, C.; Marsala, R.; Schneider, H.

    2009-01-01

    NSTX at Princeton Plasma Physics Laboratory (PPPL) requires sophisticated plasma positioning control system for stable plasma operation. TF magnetic coils and PF magnetic coils provide electromagnetic fields to position and shape the plasma vertically and horizontally respectively. NSTX utilizes twenty six coil power supplies to establish and initiate electromagnetic fields through the coil system for plasma control. A power protection and interlock system is utilized to detect power system faults and protect the TF coils and PF coils against excessive electromechanical forces, overheating, and over current. Upon detecting any fault condition the power system is restricted, and it is either prevented from initializing or suppressed to de-energize coil power during pulsing. Power fault status is immediately reported to the computer system. This paper describes the design and operation of NSTX's protection and interlocking system and possible future expansion.

  13. Evaluation and application of a fast module in a PLC based interlock and control system

    Energy Technology Data Exchange (ETDEWEB)

    Zaera-Sanz, M [Department of Physics, Mathematics and Computer Science, Higher School of Technical Sciences CEU, Universidad Cardenal Herrera, Valencia (Spain)], E-mail: manzaesan@yahoo.es

    2009-08-15

    The LHC Beam Interlock system requires a controller performing a simple matrix function to collect the different beam dump requests. To satisfy the expected safety level of the Interlock, the system should be robust and reliable. The PLC is a promising candidate to fulfil both aspects but too slow to meet the expected response time which is of the order of {mu}seconds. Siemens has introduced a 'so called' fast module (FM352-5 Boolean Processor). It provides independent and extremely fast control of a process within a larger control system using an onboard processor, a Field Programmable Gate Array (FPGA), to execute code in parallel which results in extremely fast scan times. It is interesting to investigate its features and to evaluate it as a possible candidate for the beam interlock system. This paper publishes the results of this study. As well, this paper could be useful for other applications requiring fast processing using a PLC.

  14. Evaluation of a fast PLC module in prospect of the LHC beam interlock system

    CERN Document Server

    Zaera-Sanz, Manuel

    2005-01-01

    The LHC Beam Interlock system requires a controller performing a simple matrix function to collect the different beam dump requests. To satisfy the expected safety level of the Interlock, the system should be robust and reliable. The PLC is a promising candidate to fulfil both aspects but too slow to meet the expected response time which is of the order of mseconds. Siemens has introduced a “so called” fast module (FM352-5 Boolean Processor) that provides independent and extremely fast control of a process within a larger control system using an onboard processor, a Field Programmable Gate Array (FPGA), to execute code in parallel which results in extremely fast scan times. It is interesting to investigate its features and to evaluate it as a possible candidate for the beam interlock system. This note publishes the results of this study. As well, this note could be useful for other applications requiring fast processing using a PLC.

  15. Design of Control and Interlocking System for a Typical Radar Transmitter

    Directory of Open Access Journals (Sweden)

    Nagabhushan Raju KONDURU

    2010-07-01

    Full Text Available The paper presents design and constructional features of CPLD based control and interlocking units for a typical MST radar transmitter. The conventional digital hardware used for controlling the radar transmitter and performing the interlock operations has been replaced by Xilinx’s XC9572C10PC84 CPLD device. The latest state of the art devices replace the front panel switches and LEDs display. This has resulted in miniaturizing the entire control and interlock subsystems. The necessary code is written in Verilog HDL. The newly designed system overcomes the design flaws in the earlier system hardware. The performance and results of the system have been verified with the simulation and real time testing at the plant. The unit testing is performed for more than four months with continuous operation of transmitter and the test report is highly encouraging.

  16. The engineering project and reliability research of the safety interlock slow control system in BESIII

    International Nuclear Information System (INIS)

    Zhang Yinhong; Zhao Jingwei; Li Xiaonan; Xie Xiaoxi; Gao Cuishan; Bai Jingzhi; Chen Xihui; Min Jian; Nie Zhendong

    2008-01-01

    The new safety interlock slow control system of BESIII is designed to ensure that the BESIII interior equipments and the accelerator control center to work in coordination, and to guarantee the safety of the operating staff and all the important equipments at the same time. This paper introduces the hardware and software design of safety interlock system from the engineering requirements angle, including a detailed research on the software implementation technique of the state machine on PLC and the reliability of the system. (authors)

  17. GammaCam trademark radiation imaging system

    International Nuclear Information System (INIS)

    1998-02-01

    GammaCam trademark, a gamma-ray imaging system manufactured by AIL System, Inc., would benefit a site that needs to locate radiation sources. It is capable of producing a two-dimensional image of a radiation field superimposed on a black and white visual image. Because the system can be positioned outside the radiologically controlled area, the radiation exposure to personnel is significantly reduced and extensive shielding is not required. This report covers the following topics: technology description; performance; technology applicability and alternatives; cost; regulatory and policy issues; and lessons learned. The demonstration of GammaCam trademark in December 1996 was part of the Large-Scale Demonstration Project (LSDP) whose objective is to select and demonstrate potentially beneficial technologies at the Argonne National Laboratory-East (ANL) Chicago Pile-5 Research Reactor (CP-5). The purpose of the LSDP is to demonstrate that by using innovative and improved decontamination and decommissioning (D and D) technologies from various sources, significant benefits can be achieved when compared to baseline D and D technologies

  18. Economic aspects of interlocking hollow brick system designed for industrialized building system

    Science.gov (United States)

    Tahir, Mahmood Md.; Saggaff, Anis; Ngian, Shek Poi; Sulaiman, Arizu

    2017-11-01

    Construction industry has moved forward into a technology driven where a transition is in progress from conventional method to a more advanced and mechanised system known as the Industrialised Building System (IBS). However, the need to implement the IBS should be well understood by all construction players such as designer, architect, contraction, erectors and construction workers. Therefore, there is a need to educate all these construction players which should be spearheaded by authorities such as Construction Industrial Development Board where enforcement trough building by laws as well as initiative to those that adopt the IBS in their construction. This paper reports on economic aspects of using interlocking hollow brick system in construction as an alternative method offered for Industrialized Building System. The main objective is to address the economic aspects of using interlocking block system in terms of time, costs, and utilization of manpower and to present some of the experimental tests results related to Interlocking Hollow Brick System (IHBS). Example of savings from the use of IHBS is presented in this paper by comparing the construction of two storey terrace house with build-up area of about 200 square meter with conventional construction method of typical reinforced concrete construction (RCC) compared to IHBS. The comparison shows that the implementation of IHBS can reduce construction time, cost, and utilization of man power up to 26.6% compared to the conventional method. Moreover, the construction time using IHBS can also be reduced by up to 50% as compared to the conventional construction.

  19. An overview of process instrumentation, protective safety interlocks and alarm system at the JET facilities active gas handling system

    International Nuclear Information System (INIS)

    Skinner, N.; Brennan, P.; Brown, K.; Gibbons, C.; Jones, G.; Knipe, S.; Manning, C.; Perevezentsev, A.; Stagg, R.; Thomas, R.; Yorkshades, J.

    2003-01-01

    The Joint European Torus (JET) Facilities Active Gas Handling System (AGHS) comprises ten interconnected processing sub-systems that supply, process and recover tritium from gases used in the JET Machine. Operations require a diverse range of process instrumentation to carry out a multiplicity of monitoring and control tasks and approximately 500 process variables are measured. The different types and application of process instruments are presented with specially adapted or custom-built versions highlighted. Forming part of the Safety Case for tritium operations, a dedicated hardwired interlock and alarm system provides an essential safety function. In the event of failure modes, each hardwired interlock will back-up software interlocks and shutdown areas of plant to a failsafe condition. Design of the interlock and alarm system is outlined and general methodology described. Practical experience gained during plant operations is summarised and the methods employed for routine functional testing of essential instrument systems explained

  20. Preliminary design of safety and interlock system for indian test facility of diagnostic neutral beam

    Energy Technology Data Exchange (ETDEWEB)

    Tyagi, Himanshu, E-mail: htyagi@iter-india.org [ITER-India, Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India); Soni, Jignesh [Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India); Yadav, Ratnakar; Bandyopadhyay, Mainak; Rotti, Chandramouli [ITER-India, Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India); Gahlaut, Agrajit [Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India); Joshi, Jaydeep; Parmar, Deepak [ITER-India, Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India); Bansal, Gourab; Pandya, Kaushal; Chakraborty, Arun [Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India)

    2016-11-15

    Highlights: • Indian Test Facility being built to characterize DNB for ITER delivery. • Interlock system required to safeguard the investment incurred in building the facility and protecting ITER deliverable components. • Interlock levels upto 3IL-3 identified. • Safety instrumented system for occupational safety being designed. Safety I&C functions of SIL-2 identified. • The systems are based on ITER PIS and PSS design guidelines. - Abstract: Indian Test Facility (INTF) is being built in Institute For Plasma Research to characterize Diagnostic Neutral Beam in co-operation with ITER Organization. INTF is a complex system which consists of several plant systems like beam source, gas feed, vacuum, cryogenics, high voltage power supplies, high power RF generators, mechanical systems and diagnostics systems. Out of these, several INTF components are ITER deliverable, that is, beam source, beam line components and power supplies. To ensure successful operation of INTF involving integrated operation of all the constituent plant systems a matured Data Acquisition and Control System (DACS) is required. The INTF DACS is based on CODAC platform following on PCDH (Plant Control Design Handbook) guidelines. The experimental phases involve application of HV power supplies (100 KV) and High RF power (∼800 KW) which will produce energetic beam of maximum power 6MW within the facility for longer durations. Hence the entire facility will be exposed tohigh heat fluxes and RF radiations. To ensure investment protection and to provide occupational safety for working personnel a matured Safety and Interlock system is required for INTF. The Safety and Interlock systems are high-reliability I&C systems devoted completely to the specific functions. These systems will be separate from the conventional DACS of INTF which will handle the conventional control and acquisition functions. Both, the Safety and Interlock systems are based on IEC 61511 and IEC 61508 standards as

  1. Preliminary design of safety and interlock system for indian test facility of diagnostic neutral beam

    International Nuclear Information System (INIS)

    Tyagi, Himanshu; Soni, Jignesh; Yadav, Ratnakar; Bandyopadhyay, Mainak; Rotti, Chandramouli; Gahlaut, Agrajit; Joshi, Jaydeep; Parmar, Deepak; Bansal, Gourab; Pandya, Kaushal; Chakraborty, Arun

    2016-01-01

    Highlights: • Indian Test Facility being built to characterize DNB for ITER delivery. • Interlock system required to safeguard the investment incurred in building the facility and protecting ITER deliverable components. • Interlock levels upto 3IL-3 identified. • Safety instrumented system for occupational safety being designed. Safety I&C functions of SIL-2 identified. • The systems are based on ITER PIS and PSS design guidelines. - Abstract: Indian Test Facility (INTF) is being built in Institute For Plasma Research to characterize Diagnostic Neutral Beam in co-operation with ITER Organization. INTF is a complex system which consists of several plant systems like beam source, gas feed, vacuum, cryogenics, high voltage power supplies, high power RF generators, mechanical systems and diagnostics systems. Out of these, several INTF components are ITER deliverable, that is, beam source, beam line components and power supplies. To ensure successful operation of INTF involving integrated operation of all the constituent plant systems a matured Data Acquisition and Control System (DACS) is required. The INTF DACS is based on CODAC platform following on PCDH (Plant Control Design Handbook) guidelines. The experimental phases involve application of HV power supplies (100 KV) and High RF power (∼800 KW) which will produce energetic beam of maximum power 6MW within the facility for longer durations. Hence the entire facility will be exposed tohigh heat fluxes and RF radiations. To ensure investment protection and to provide occupational safety for working personnel a matured Safety and Interlock system is required for INTF. The Safety and Interlock systems are high-reliability I&C systems devoted completely to the specific functions. These systems will be separate from the conventional DACS of INTF which will handle the conventional control and acquisition functions. Both, the Safety and Interlock systems are based on IEC 61511 and IEC 61508 standards as

  2. Towards a Framework for Modelling and Verification of Relay Interlocking Systems

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth

    2011-01-01

    This paper describes a framework currently under development for modelling, simulation, and verification of relay interlocking systems as used by the Danish railways. The framework is centred around a domain-specific language (DSL) for describing such systems, and provides (1) a graphical editor...

  3. Control and Interlocking System for Bending Magnet Front-end at Indus-2

    Science.gov (United States)

    Kane, Sanjeev R.; Garg, Chander Kant; Nandedkar, R. V.

    2007-01-01

    We present control and interlock system developed for Indus-2 bending magnet front-end. The paper describes in detail the control of various signals associated with the front-end and the interlocking scheme implemented for the installed front-end. The number of signals associated with each front-end is ˜ 75. A control system is designed for monitoring temperature, pressure, airflow, water flow and control of vacuum gauges, fast shutter, water cooled shutter, safety shutter, pneumatic gate valves, sputter ion pump power supplies, beam position monitor etc. Two independent signals are generated for critical components that are used for software interlock and hard-wired interlock. The front-end control system is VME based and window 2000/XP workstation as an operator console. The CPU used is Motorola 68000-processor board of the VME bus having OS-9 real time operating system. One VME crate serves a cluster of 2-3 front ends. The communication between the VME and the workstation is linked over RS232 serial communication. The sputter ion power supplies are connected over isolated RS485 network. Critical protection features are implemented so that no single failure can render the system unsafe. This is implemented by providing two independent chains of protection (1) Hard wired in which relay logic is used and (2) Software. A Graphical User Interface (GUI) is developed using Lab view Version 7.0.

  4. Software Verification and Validation Test Report for the HEPA filter Differential Pressure Fan Interlock System

    International Nuclear Information System (INIS)

    ERMI, A.M.

    2000-01-01

    The HEPA Filter Differential Pressure Fan Interlock System PLC ladder logic software was tested using a Software Verification and Validation (VandV) Test Plan as required by the ''Computer Software Quality Assurance Requirements''. The purpose of his document is to report on the results of the software qualification

  5. Architecture for interlock systems: reliability analysis with regard to safety and availability

    International Nuclear Information System (INIS)

    Wagner, S.; Apollonio, A.; Schmidt, R.; Zerlauth, M.; Vergara-Fernandez, A.

    2012-01-01

    For particle accelerators like LHC and other large experimental physics facilities like ITER, the machine protection relies on complex interlock systems. In the design of interlock loops for the signal exchange in machine protection systems, the choice of the hardware architecture impacts on machine safety and availability. The reliable performance of a machine stop (leaving the machine in a safe state) in case of an emergency, is an inherent requirement. The constraints in terms of machine availability on the other hand may differ from one facility to another. Spurious machine stops, lowering machine availability, may to a certain extent be tolerated in facilities where they do not cause undue equipment wear-out. In order to compare various interlock loop architectures in terms of safety and availability, the occurrence frequencies of related scenarios have been calculated in a reliability analysis, using a generic analytical model. This paper presents the results and illustrates the potential of the analysis method for supporting the choice of interlock system architectures. The results show the advantages of a 2003 (3 redundant lines with 2-out-of-3 voting) over the 6 architectures under consideration for systems with high requirements in both safety and availability

  6. The multi-interlock and check of logical system for 5 MW low power reactor automatic rod

    International Nuclear Information System (INIS)

    Li Guangjian; Zhao Zengqiao

    1992-01-01

    The safety and reliability of the logical system for 5 MW LPR automatic rod are improved, because of using multi-interlock and manual check on line. The design character and function of the logical system are introduced

  7. Design lessons from using programmable controllers in the MFTF-BETA Personnel Safety and Interlocks System

    International Nuclear Information System (INIS)

    Branum, J.D.

    1983-01-01

    Applying programmable controllers in critical applications such as personnel safety and interlocks systems requires special considerations in the design of both hardware and software. All modern programmable controller systems feature extensive internal diagnostic capabilities to protect against problems such as program memory errors; however most, if not all present designs lack an intrinsic capability for detecting and countering failures on the ''field-side'' of their I/O modules. Many of the most common styles of I/O modules can also introduce potentially dangerous sneak circuits, even without component failure. This paper presents the most significant lessons learned to date in the design of the MFTF-BETA Personnel Safety and Interlocks System, which utilizes two non-redundant programmable controllers with over 800 I/O points each. Specific problems recognized during the design process as well as those discovered during initial testing and operation are discussed along with their specific solutions in hardware and software

  8. Design lessons from using programmable controllers in the MFTF-B personnel safety and interlocks system

    International Nuclear Information System (INIS)

    Branum, J.D.

    1983-01-01

    Applying programmable controllers in critical applications such as personnel safety and interlocks systems requires special considerations in the design of both hardware and software. All modern programmable controller systems feature extensive internal diagnostic capabilities to protect against problems such as program memory errors; however most, if not all present designs lack an intrinsic capability for detecting and countering failures on the field-side of their I/O modules. Many of the most common styles of I/O modules can also introduce potentially dangerous sneak circuits, even without component failure. This paper presents the most significant lessons learned to date in the design of the MFTF-B Personnel Safety and Interlocks System, which utilizes two non-redundant programmable controllers with over 800 I/O points each. Specific problems recognized during the design process as well as those discovered during initial testing and operation are discussed along with their specific solutions in hardware and software

  9. Control interlock and monitoring system for 80 KW IOT based RF power amplifier system at 505.812 MHz for Indus-2

    International Nuclear Information System (INIS)

    Kumar, Gautam; Deo, R.K.; Jain, M.K.; Bagre, Sunil; Hannurkar, P.R.

    2013-01-01

    For 80 kW inductive output tube (IOT) based RF power amplifier system at 505.812 MHz for Indus-2, a control, interlock and monitoring system is realized. This is to facilitate proper start-up and shutdown of the amplifier system, monitor various parameters to detect any malfunction during its operation and to bring the system in a safe stage, thereby assuring reliable operation of the amplifier system. This high power amplifier system incorporates interlocks such as cooling interlocks, various voltage and current interlocks and time critical RF interlocks. Processing of operation sequence, cooling interlocks and various voltage and current interlocks have been realized by using Siemens make S7-CPU-315-2DP (CPU) based programmable logic controller (PLC) system. While time critical or fast interlocks have been realized by using Siemens make FPGA based Boolean Co-processor FM-352-5 which operates in standalone mode. Siemens make operating panel OP277 6'' is being used as a human machine interface (HMI) device for command, data, alarm generation and process parameter monitoring. (author)

  10. Application of programmable controllers to vacuum system interlocks

    International Nuclear Information System (INIS)

    Lee, G.; Moore, D.

    1979-11-01

    This paper describes the Doublet III Vacuum Control System in which all input signals and output loads are connected to a programmable controller (PC) for logical interfacing. Input signals derived from CAMAC, control panels, limit switches, etc., are implemented as output signals to CAMAC, vacuum valves, pump motors, etc., according to a logic program stored in the PC memory. The memory can be easily programmed by anyone familar with either Boolean algebra or relay-ladder network diagrams. The program data is entered with the aid of a calculator like, keyboard instrument with LED readout displays. The PC system contains a 1024 word RAM memory with a battery backup system to provide 72 hours protection of contents in case of power failure

  11. A review on past and present development on the interlocking loadbearing hollow block (ILHB) system

    Science.gov (United States)

    Bosro, M. Z. M.; Samad, A. A. A.; Mohamad, N.; Goh, W. I.; Tambichik, M. A.; Iman, M. A.

    2018-04-01

    Massive migration and increasing population in Malaysia has contributed to the increasing demand of quality and affordable housing. Over the past 50 years, the Malaysian housing industry has seen the growth of using conventional construction system such as reinforced concrete frame structures and bricks. The conventional system, as agreed by many researchers, causes delays and other disadvantages in some of the construction projects. Thus, the utilization of interlocking loadbearing hollow block (ILHB) system is needed to address these issues. This system has been identified as an alternative and sustainable building system for the construction industry in Malaysia which the PUTRA block system is the latest example of the ILHB developed. The system offers various advantages in terms of speed and cost in construction, strength, environmentally friendly and aesthetic qualities. Despite these advantages, this system has not been practically applied and develop in Malaysia. Therefore, this paper aims to review the past and present development of the interlocking loadbearing hollow block (ILHB) system that available locally and globally.

  12. The Use of UML to Development of a Railway Interlocking System

    Directory of Open Access Journals (Sweden)

    Karol Rastocny

    2003-01-01

    Full Text Available The paper deals with problems of using the Unifield Modeling Lanfuage (UML in developmentt of new railway interlocking and signalling systems. A simplifield example of the control circuit of a point machine is used to demonstrate an object-oriented approach to specifying the functional safety requirements. An informal specification given by the relevant technical standart is used as a starting point and results in semi-formal specification based on UML model. Advantages of the presented approach are discussed and new trends of increasing formality of UML models are indicated within conclusions.

  13. Successful commissioning of an electronic interlocking system, taking the example of Plochingen; Erfolgreiche Inbetriebnahme eines elektronischen Stellwerks - Beispiel ESTW Plochingen

    Energy Technology Data Exchange (ETDEWEB)

    Woerner, C.; Rosenberger, H. [DB ProjektBau GmbH, Stuttgart (Germany); Kuehnle, T. [THOST Projektmanagement GmbH, Pforzheim (Germany)

    2007-03-15

    It was essential to draw up a precise commissioning concept for the new electronic interlocking system in Plochingen, given the scale of the measure and the high frequency of trains passing through. The authors describe the detailed documents that were compiled to begin with, dealing, in particular, with technical and operational feasibility and time requirements. Such an input was a precondition for the commissioning operation to be completed smoothly. Thanks to this concept and the committed work of all those involved at first hand, commissioning the new electronic interlocking system in Plochingen was completed within the five night-time line closures planned for it between 13 and 18 April 2006. (orig.)

  14. Radiation interlocks: The choice between conventional hard-wired logic and computer-based systems

    International Nuclear Information System (INIS)

    Crook, K.F.

    1986-11-01

    During the past few years, the use of computers in radiation safety systems has become more widespread. This is not surprising given the ubiquitous nature of computers in the modern technological world. But is a computer a good choice for the central logic element of a personnel safety system. Recent accidents at computer controlled medical accelerators would indicate that extreme care must be exercised if malfunctions are to be avoided. The Department of Energy has recently established a sub-committee to formulate recommendations on the use of computers in safety systems for accelerators. This paper will review the status of the committee's recommendations, and describe radiation protection interlock systems as applied to both accelerators and to irradiation facilities. Comparisons are made between the conventional relay approach and designs using computers. 6 refs., 6 figs

  15. An active interlock system for the NSLS x-ray ring insertion devices

    International Nuclear Information System (INIS)

    Nawrocky, R.J.; Biscardi, R.; Dabrowski, J.; Flannigan, J.; Ramamoorthy, S.; Rothman, J.; Smith, J.; So, I.; Thomas, M.; Decker, G.

    1991-01-01

    This paper describes the design and operation of an active interlock system which has been installed in the NSLS X-ray electron storage ing to protect the vacuum chamber from thermal damage by mis-steered high power photon beams from insertion devices (IDs). the system employs active beam position detectors to monitor beam motion in the ID straight sections and solid state logic circuitry to ''dump'' the stored beam in the event of a fault condition by interrupting the rf. To ensure a high degree of reliability, redundancy and continuous automatic checking has been incorporated into the design. Overall system integrity is checked periodically with beam at safe levels of beam current. 2 refs., 3 figs

  16. Groovy as Domain-Specific Language in the Software Interlock System

    CERN Document Server

    Wozniak, J; Kruk, G

    2014-01-01

    After over 7 years in operation the Software Interlock System (SIS) has become an indispensable and mission critical controls tool covering many operational areas from general machine protection to diagnostics. The growing number of running instances as much as the size of existing configurations have increased both the complexity and maintenance cost of running the SIS infrastructure. In response to those issues, new ways of configuring the system have been investigated aiming at simplifying the configuration process by making it faster, more user-friendly and understandable for wider audiences and domain experts alike. As one of the possible choices the Groovy scripting language has been considered as being particularly well suited for writing a custom Domain-Specific Language (DSL) due to its built-in language features like native syntax constructs, command chain expressions, hierarchical structures with builders, closures or Abstract Syntax Tree (AST) transformations. This document explains best practices...

  17. design analysis of cam-follower system for beat up motion

    African Journals Online (AJOL)

    User

    A cam swing roller-follower mechanism is designed for the beat-up motion of a horizontal narrow loom. The system consists of a radial plate-cam driven by a camshaft keyed to the plate cam. A slay bar which act as the beater is attached to the radial swing roller-follower and assembled on the plate cam. A continuous ...

  18. Development of Remote Control and Interlock System for the PEFP Microwave Ion Source

    International Nuclear Information System (INIS)

    Song, Young Gi; Seol, Kyung Tae; Kwon, Hyeok Jung; Jang, Ji Ho; Cho, Yong Sub

    2011-01-01

    The control system for a microwave ion source as an isolated high voltage device is a main part of the PEFP distributed control system. The system is used to control two sets of microwave ion sources, the remote control and the interlock system. A VME system with an embedded Power PC CPU is used as main computer. The VME system is dedicated to control and monitoring of the ion source operation. An isolated control system has been designed and developed for remote control and monitoring of a microwave generator and various power supplies. As the source is placed on high voltage platform, optical fiber isolation has been used between the serial to optical fiber VME I/O board and the control system on the high voltage platform. These are connected through RS232 serial interface. A fast Ethernet is used to communicate between the microwave ion source control system and other control stations in the PEFP control system. EPICS toolkit is adopted to provide network programming and user interface by using EPICS Channel Access (CA)

  19. CAMAC-based interlock system for power-supply-hardware protection on MFTF

    International Nuclear Information System (INIS)

    Strauch, M.S.

    1981-01-01

    This interlock module accepts 16 inputs and generates, in conjunction with an internal PROM map, 8 outputs. This decision process is autonomous of the CAMAC dataway and host computer. The map is generated, burned and verified by a user interactive program written to accept input/output equations in Boolean algebra. The interlock module requires the host computer to periodically interrogate it to verify proper operation of the module, host computer and date link; otherwise, permissives are dropped. An internal mask register may be used to override interlock inputs. This mask is perishable and must be constantly refreshed. Output drivers may be operated in a latch/no latch mode. This prevents outputs, once dropped, from being reasserted even if the proper input sequence is reestablished. A first-out register may be utilized to determine which input has dropped first in the event that chain reactions are developed among the interlock inputs

  20. Active interlock system for high power insertion devices in the x-ray ring

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    In modern synchrotron radiation rings photon beams generated by high power insertion devices (IDs) may be sufficiently intense to cause severe thermal damage to the machine vacuum chamber if mis-steered. Thus when operating a storage ring with the IDs, great care must be exercised to prevent mis-steering of the electron beam orbit. At present, the X-ray ring operates with three IDs, namely two hybrid wigglers (HBW) at X-21 and X-25,a nd a 5-Tesla superconducting wiggler at X-17. All wigglers are located in low-beta straight sections. In the straight sections. In the straight sections, beam orbit may be deflected by as much as ±8 mrad without scraping the chamber wall. For various reasons it was not possible to design the X-ray ring vacuum chamber to be safe under all possible operating conditions, however, the chamber is safe for i < 7 mA, all horizontal beam deflection angles and for vertical angles < ± 2.5 mrad. To protect the machine vacuum chamber from damage due to mis-steered beams, and interlock system has been developed and installed. This system utilizes active beam position detectors which continuously monitor beam motion in each of the ID straight sections and logic circuitry which interrupts the RF and dumps the stored beam in the case of a fault

  1. Elaboration of the configuration and programming of the interlocks system of the TRIGA Mark III reactor

    International Nuclear Information System (INIS)

    Mejia C, M. A.

    2016-01-01

    The modernization of the TRIGA Mark III reactor interlock system requires a system that provides high reliability, flexibility and ease of operation during reactor operation. With this modernization of the system, is intended to prevent, control and mitigate the causes of probable accidents reported in the reactor accident analysis. On the other hand, is foreseen the ease reactor operation in a simple, safe and efficient way. The programmable logic controller can be programmed by programming instructions using simple language and easy to develop, these can be modified from a computer using the programming software. In addition, another of the advantages offered by the controller is that can be modified from a touch screen (human-machine interface) that allows adjustment, without the need to use programming software and diagnostic functions during the process. As a result of the present work, a situation of improvement in the reactor operation was generated, facilitating the handling of the bridge and increasing the efficiency of the system in the execution of the operating conditions of the installations external to the reactor. A modern, more reliable and much less expensive system was achieved than the previous one, avoiding that the maintenance to the system generates high expenses. With respect to the development of the application programming, a control was implemented that allows to select a zone of the five that have inside the pool to carry out the displacement of automatic way and later to be located in that zone, having in this way a greater efficiency and ease in bridge control. (Author)

  2. Early Clinical Experience with a Newly Designed Interlocking Nail System-Targon(®) Vet.

    Science.gov (United States)

    Brückner, Michael; Unger, Martin; Spies, Markus

    2016-08-01

    To describe early clinical experience with a newly designed interlocking nail system (Targon(®) Vet) in diaphyseal fractures in cats and small dogs. Retrospective case series. Client-owned cats (n=49) and dogs (n=8). Fifty-seven consecutive cases (49 cats, 8 dogs) with 60 long bone fractures were included in the study. Follow-up radiographs were scheduled at 4 and 8 weeks and again 6 months postoperatively. The end point for each case was determined radiographically by a healed fracture. Complications were defined as minor or major. Clinical outcome was subjectively assessed by a full orthopedic examination and follow-up radiographs. Descriptive data are reported. Median age of cats was 18 months (range, 3-220 months) and of dogs was 28 months (range, 7-115 months). Median body weight was 3.7 kg (range, 1.67-8.41 kg) for cats and 8.15 kg (range, 2.68-13.6 kg) for dogs. Median radiographic follow-up was 16 weeks. All fractures with follow-up radiographs available (n=46) were healed with no infections reported. A total of 12 postoperative complications occurred: 3 minor (slippage of the locking screws) and 9 major (5 femoral-irritation of the sciatic nerve, stress protection, fracture because of a missed fissure, femoral neck fracture, intra-operative revision with a rod and plate; 4 tibial-3 with protrusion of the distal locking screw through the skin and 1 with in-growth of the intramedullary nail). Implantation of the Targon(®) Vet System was feasible in all cases. It provides an alternative system for diaphyseal fracture repair in cats and small dogs. © Copyright 2016 by The American College of Veterinary Surgeons.

  3. Fibre Monitoring System for the Beam Permit Loops at the LHC and Future Evolution of the Beam Interlock System

    CERN Document Server

    García-Argos, Carlos; Gabourin, Stéphane; Martin, Christophe; Puccio, Bruno; Siemko, Andrzej P.

    The optical fibres that transmit the beam permit loop signals at the CERN accelerator complex are deployed along radiation areas. This may result in increased attenuation of the fibres, which reduces the power margin of the links. In addition, other events may cause the links to not function properly and result in false dumps, reducing the availability of the accelerator chain and affecting physics data taking. In order to evaluate the state of the fibres, an out-of-band fibre monitoring system is proposed, working in parallel to the actual beam permit loops. The future beam interlock system to be deployed during LHC long shutdown 2 will implement online, real-time monitoring of the fibres, a feature the current system lacks. Commercial off-the-shelf components to implement the optical transceivers are proposed whenever possible instead of ad-hoc designs.

  4. 21 CFR 872.3661 - Optical Impression Systems for CAD/CAM.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices § 872.3661 Optical Impression Systems for CAD... (CAD/CAM) is a device used to record the topographical characteristics of teeth, dental impressions, or... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Optical Impression Systems for CAD/CAM. 872.3661...

  5. An open CAM system for dentistry on the basis of China-made 5-axis simultaneous contouring CNC machine tool and industrial CAM software.

    Science.gov (United States)

    Lu, Li; Liu, Shusheng; Shi, Shenggen; Yang, Jianzhong

    2011-10-01

    China-made 5-axis simultaneous contouring CNC machine tool and domestically developed industrial computer-aided manufacture (CAM) technology were used for full crown fabrication and measurement of crown accuracy, with an attempt to establish an open CAM system for dental processing and to promote the introduction of domestic dental computer-aided design (CAD)/CAM system. Commercially available scanning equipment was used to make a basic digital tooth model after preparation of crown, and CAD software that comes with the scanning device was employed to design the crown by using domestic industrial CAM software to process the crown data in order to generate a solid model for machining purpose, and then China-made 5-axis simultaneous contouring CNC machine tool was used to complete machining of the whole crown and the internal accuracy of the crown internal was measured by using 3D-MicroCT. The results showed that China-made 5-axis simultaneous contouring CNC machine tool in combination with domestic industrial CAM technology can be used for crown making and the crown was well positioned in die. The internal accuracy was successfully measured by using 3D-MicroCT. It is concluded that an open CAM system for dentistry on the basis of China-made 5-axis simultaneous contouring CNC machine tool and domestic industrial CAM software has been established, and development of the system will promote the introduction of domestically-produced dental CAD/CAM system.

  6. Definition and means of maintaining the process vacuum liquid detection interlock systems portion of the PFP safety envelope

    International Nuclear Information System (INIS)

    THOMAS, R.J.

    1999-01-01

    The Process Vacuum Liquid Detection interlock systems prevent intrusion of process liquids into the HEPA filters downstream of demisters No.6 and No.7 during Process Vacuum System operation. This prevents liquid intrusion into the filters, which could cause a criticality. The Safety Envelope (SE) includes the equipment, which detects the presence of liquids in the vacuum headers; isolates the filters; shuts down the vacuum pumps; and alarms the condition. This report identifies the equipment in the SE operating, maintenance, and surveillance procedures needed to maintain the SE equipment; and rationale for exclusion of some equipment and testing from the SE

  7. Reliability Analysis of the new Link between the Beam Interlock System and the LHC Beam Dumping System Zuverlässigkeitsanalyse der neuen Verbindung zwischen dem Beam Interlock System und dem LHC Beam Dumping System

    CERN Document Server

    Vatansever, Volkan

    The nominal stored energy in each LHC beam is 360 MJ, surpassing the beam energy of other accelerators by orders of magnitude. This energy threatens to damage accelerator components in case of uncontrolled beam losses To avoid damage of accelerator equipment due to impacting beam, the controlled removal of the LHC beams from the collider rings towards the dump block must be guaranteed at all times. Therefore, the LHC Beam Dumping System was built according to high reliability standards. To further reduce the risk of incapability to dump the beams in case of correlated failures in the redundant system, a new direct link from the LHC Beam Interlock System to the Re-triggering Lines of the LHC Beam Dumping System will be implemented for the startup with beam in 2015. This link represents a diverse redundancy to the current implementation, which should neither significantly increase the risk for so-called Asynchronous Beam Dumps nor compromise machine availability. Therefore, a reliability analysis down to the co...

  8. 40 Gbps data acquisition system for NectarCAM

    Science.gov (United States)

    Hoffmann, Dirk; Houles, Julien; NectarCAM Team; CTA Consortium, the

    2017-10-01

    The Cherenkov Telescope Array (CTA) will be the next generation ground-based gamma-ray observatory. It will be made up of approximately 100 telescopes of three different sizes, from 4 to 23 meters in diameter. The previously presented prototype of a high speed data acquisition (DAQ) system for CTA (CHEP 2012, [6]) has become concrete within the NectarCAM project, one of the most challenging camera projects with very demanding needs for bandwidth of data handling. We designed a Linux-PC system able to concentrate and process without packet loss the 40 Gb/s average data rate coming from the 265 Front End Boards (FEB) through Gigabit Ethernet links, and to reduce data to fit the two ten-Gigabit Ethernet downstream links by external trigger decisions as well as custom tailored compression algorithms. Within the given constraints, we implemented de-randomisation of the event fragments received as relatively small UDP packets emitted by the FEB, using off-the-shelf equipment as required by the project and for an operation period of at least 30 years. We tested out-of-the-box interfaces and used original techniques to cope with these requirements, and set up a test bench with hundreds of synchronous Gigabit links in order to validate and tune the acquisition chain including downstream data logging based on zeroMQ and Google ProtocolBuffers [8].

  9. SaRDIn - A Safe Reconfigurable Distributed Interlocking

    DEFF Research Database (Denmark)

    Fantechi, Alessandro; Gnesi, S.; Haxthausen, Anne Elisabeth

    2016-01-01

    Current computer-based interlocking systems most often have a centralized design, with all logic residing in a single computer. Centralized interlockings are complex to design. Following the general trend in Cyber-Physical Systems, the SaRDIn (Safe Reconfigurable Distributed Interlockings) concept...

  10. Automated generation of formal safety conditions from railway interlocking tables

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth

    2014-01-01

    This paper describes a tool for extracting formal safety conditions from interlocking tables for railway interlocking systems. The tool has been applied to generate safety conditions for the interlocking system at Stenstrup station in Denmark, and the SAL model checker tool has been used to check...

  11. Digital Dentistry — Digital Impression and CAD/CAM System Applications

    Directory of Open Access Journals (Sweden)

    Gabor Alin-Gabriel

    2017-03-01

    Full Text Available Digital imprint and computer-aided design/computer-aided manufacture (CAD/CAM systems offer several benefits compared to traditional techniques. The use of a CAD/CAM system to scan preparations and generate restorations in-office, removes a second appointment for the patient. The existence of precision benefits in using complete systems and chairside scanning systems, has been proven. CAD/CAM restorations have a good longevity and meet the accepted clinical parameters. New digital impression methods are presently accessible, and before long, the long-awaited goal of sparing patients of one the most unpleasant practices in clinical dentistry, acquiring dental impressions, will be exchanged by intraoral digital scanning. CAD/CAM systems existing nowadays, can feed data through accurate digital scans created from plaster models, straight to manufacturing systems that can shape ceramic or resin restorations with no requirement of a physical copy of the prepared, adjacent, and antagonist teeth.

  12. An in vitro biomechanical investigation of an interlocking nail system developed for buffalo tibia.

    Science.gov (United States)

    Bhat, S A; Aithal, H P; Kinjavdekar, P; Amarpal; Zama, M M S; Gope, P C; Pawde, A M; Ahmad, R A; Gugjoo, M B

    2014-01-01

    The objectives of the study were to determine the mechanical properties of a customized buffalo interlocking nail (BIN), intact buffalo tibia, and ostectomized tibia stabilized with BIN in different configurations, as well as to assess the convenience of interlocking nailing in buffalo tibia. The BIN (316L stainless steel, 12 mm diameter, 250 mm long, nine-hole solid nails with 10° proximal bend) alone was loaded in compression and three-point bending (n=4 each); intact tibiae and ostectomized tibiae (of buffaloes aged 5-8 years, weighing 300-350 kg) stabilized with BIN using 4.9 mm standard or modified locking bolts (4 or 8) in different configurations were subjected to axial compression, cranio-caudal three-point bending and torsion (n=4 each) using a universal testing machine. Mechanical parameters were determined from load-displacement curves and compared using Kruskal-Wallis test (ptesting modes. The strength of fixation constructs with eight locking bolts was significantly more than with four bolts. Overall strength of fixation with modified locking bolts was better than standard bolts. Based on technical ease and biomechanical properties, cranio-caudal insertion of bolts into the bone was found better than medio-lateral insertion. The eight bolt BIN-bone constructs could be useful to treat tibial fractures in large ruminants, especially buffaloes.

  13. Coupling the Community Atmospheric Model (CAM) with the Statistical Spectral Interpolation (SSI) System under ESMF

    Science.gov (United States)

    daSilva, Arlindo

    2004-01-01

    The first set of interoperability experiments illustrates the role ESMF can play in integrating the national Earth science resources. Using existing data assimilation technology from NCEP and the National Weather Service, the Community Atmosphere Model (CAM) was able to ingest conventional and remotely sensed observations, a capability that could open the door to using CAM for weather as well as climate prediction. CAM, which includes land surface capabilities, was developed by NCAR, with key components from GSFC. In this talk we will describe the steps necessary for achieving the coupling of these two systems.

  14. The use of microprocessors at TRIUMF in the control of radiation safety interlock systems

    International Nuclear Information System (INIS)

    King, L.

    1988-01-01

    At TRIUMF the cyclotron vault, all primary beam lines, and each experimental area has a dedicated control unit to manage the safety interlock control of the area lockup sequence, beam blocker drive and area access. Typically each area has 24 devices which are monitored to control 16 outputs. These control units (Area Safety Units) were first implemented through the use of relay logic. The relay logic was reliable but difficult to modify to incorporate changes to the areas. In 1979 it was decided to use microprocessors in the form of single board computers to control the Area Safety Units. The details of the hardware and software is discussed as well as the advantages of microprocessor control

  15. Control/interlock/display system for EBT-P using commercially-available hardware and firmware

    International Nuclear Information System (INIS)

    Schmitt, R.J.

    1983-01-01

    For the EBT-P project, alternative commercially-available hardware, software and firmware have been employed for control, interlock and data display functions. This paper describes the criteria and rationale used to select that commercial equipment and discusses the important features of the equipment chosen, especially programmable controllers. Additional discussion is centered on interface problems which are encountered upon attempts to integrate equipment from several vendors. Some solutions to these problems are discussed. Details of software and hardware performance during tests are presented. The extent to which the EBT-P hardware and software configuration addresses and resolves various issues is discussed. Several areas have been uncovered in which relatively slight improvements/modifications of commercial programmable controller firmware would significantly improve the capability of this type of hardware in fusion control applications. These improvements are discussed in detail

  16. Bending and torsional stiffness in cadaver humeri fixed with a self-locking expandable or interlocking nail system: a mechanical study.

    Science.gov (United States)

    Blum, Jochen; Karagül, Göksen; Sternstein, Werner; Rommens, Pol M

    2005-09-01

    This study was designed to gain data about a new expandable, noninterlocked intramedullary nail's capacity to stabilize unstable transverse humeral shaft fractures without the need for interlocking, thus making nail implantation simpler and to prove our goal hypothesis: that in a midshaft osteotomy of the humeral shaft the expandable humeral nail will show the same bending and torsional stiffness as an interlocked humeral nail, when implanted correctly according to the manufacturer's instructions. Pair randomization. Mechanical laboratory testing. Eight pairs of freshly harvested cadaveric humeri. Fracture model was a midshaft transverse osteotomy, gapped to 3 mm. Each humerus pair received an expandable humeral nail (Fixion) or an interlocked humerus nail (Synthes) through a retrograde approach. The humeri were fixed in polymethylmethacrylate cylinders and tested in a servo-pneumatic material-testing machine. Torsional stiffness and bending stiffness of the nail-bone-construction. Expandable nails (interlocked nails) showed a lateral bending stiffness of 0.73 +/- 0.14 (0.63 +/- 0.1) KN/mm (P = 0.026) and a frontal bending stiffness of 0.67 +/- 0.18 (0.58 +/- 0.09) KN/mm (P = 0.084). Torsional stiffness values were 0.13 +/- 0.19 (0.43 +/- 0.09 Nm/degrees) (P = 0.012). Lower torsional stiffness in the expandable nail group was observed in humeri with a funnel shaped proximal intramedullary canal. The nail systems showed similar characteristics for frontal bending (P = 0.084), but not for lateral bending (P = 0.026). For lateral bending, the Fixion nail showed significantly more stiffness than the UHN nail (P = 0.026). There was significantly lower torsional stiffness with expandable nails compared with interlocked nails. Clinical correlation would suggest that in rotationally unstable fractures (A2 and A3 diaphyseal fractures), interlocked nails would provide increased stability over expandable nails.

  17. CamOn: A Real-Time Autonomous Camera Control System

    DEFF Research Database (Denmark)

    Burelli, Paolo; Jhala, Arnav Harish

    2009-01-01

    This demonstration presents CamOn, an autonomous cam- era control system for real-time 3D games. CamOn employs multiple Artificial Potential Fields (APFs), a robot motion planning technique, to control both the location and orienta- tion of the camera. Scene geometry from the 3D environment...... contributes to the potential field that is used to determine po- sition and movement of the camera. Composition constraints for the camera are modelled as potential fields for controlling the view target of the camera. CamOn combines the compositional benefits of constraint- based camera systems, and improves...... on real-time motion planning of the camera. Moreover, the recasting of camera constraints into potential fields is visually more accessible to game designers and has the potential to be implemented as a plug-in to 3D level design and editing tools currently avail- able with games. Introduction...

  18. Outsourcing the development of specific application software using the ESA software engineering standards the SPS software Interlock System

    CERN Document Server

    Denis, B

    1995-01-01

    CERN is considering outsourcing as a solution to the reduction of staff. To need to re-engineer the SPS Software Interlock System provided an opportunity to explore the applicability of outsourcing to our specific controls environment and the ESA PSS-05 standards were selected for the requirements specification, the development, the control and monitoring and the project management. The software produced by the contractor is now fully operational. After outlining the scope and the complexity of the project, a discussion on the ESA PSS-05 will be presented: the choice, the way these standards improve the outsourcing process, the quality induced but also the need to adapt them and their limitation in the definition of the customer-supplier relationship. The success factors and the difficulties of development under contract will also be discussed. The maintenance aspect and the impact on in-house developments will finally be addressed.

  19. Interlocking wettable ceramic tiles

    Science.gov (United States)

    Tabereaux, Jr., Alton T.; Fredrickson, Guy L.; Groat, Eric; Mroz, Thomas; Ulicny, Alan; Walker, Mark F.

    2005-03-08

    An electrolytic cell for the reduction of aluminum having a layer of interlocking cathode tiles positioned on a cathode block. Each tile includes a main body and a vertical restraining member to prevent movement of the tiles away from the cathode block during operation of the cell. The anode of the electrolytic cell may be positioned about 1 inch from the interlocking cathode tiles.

  20. Coastal protection using topological interlocking blocks

    Science.gov (United States)

    Pasternak, Elena; Dyskin, Arcady; Pattiaratchi, Charitha; Pelinovsky, Efim

    2013-04-01

    The coastal protection systems mainly rely on the self-weight of armour blocks to ensure its stability. We propose a system of interlocking armour blocks, which form plate-shape assemblies. The shape and the position of the blocks are chosen in such a way as to impose kinematic constraints that prevent the blocks from being removed from the assembly. The topological interlocking shapes include simple convex blocks such as platonic solids, the most practical being tetrahedra, cubes and octahedra. Another class of topological interlocking blocks is so-called osteomorphic blocks, which form plate-like assemblies tolerant to random block removal (almost 25% of blocks need to be removed for the assembly to loose integrity). Both classes require peripheral constraint, which can be provided either by the weight of the blocks or post-tensioned internal cables. The interlocking assemblies provide increased stability because lifting one block involves lifting (and bending) the whole assembly. We model the effect of interlocking by introducing an equivalent additional self-weight of the armour blocks. This additional self-weight is proportional to the critical pressure needed to cause bending of the interlocking assembly when it loses stability. Using beam approximation we find an equivalent stability coefficient for interlocking. It is found to be greater than the stability coefficient of a structure with similar blocks without interlocking. In the case when the peripheral constraint is provided by the weight of the blocks and for the slope angle of 45o, the effective stability coefficient for a structure of 100 blocks is 33% higher than the one for a similar structure without interlocking. Further increase in the stability coefficient can be reached by a specially constructed peripheral constraint system, for instance by using post-tension cables.

  1. Alcohol ignition interlock programs.

    Science.gov (United States)

    Beirness, D J; Marques, P R

    2004-09-01

    The alcohol ignition interlock is an in-vehicle DWI control device that prevents a car from starting until the operator provides a breath alcohol concentration (BAC) test below a set level, usually .02% (20 mg/dl) to .04% (40 mg/dl). The first interlock program was begun as a pilot test in California 18 years ago; today all but a few US states, and Canadian provinces have interlock enabling legislation. Sweden has recently implemented a nationwide interlock program. Other nations of the European Union and as well as several Australian states are testing it on a small scale or through pilot research. This article describes the interlock device and reviews the development and current status of interlock programs including their public safety benefit and the public practice impediments to more widespread adoption of these DWI control devices. Included in this review are (1) a discussion of the technological breakthroughs and certification standards that gave rise to the design features of equipment that is in widespread use today; (2) a commentary on the growing level of adoption of interlocks by governments despite the judicial and legislative practices that prevent more widespread use of them; (3) a brief overview of the extant literature documenting a high degree of interlock efficacy while installed, and the rapid loss of their preventative effect on repeat DWI once they are removed from the vehicles; (4) a discussion of the representativeness of subjects in the current research studies; (5) a discussion of research innovations, including motivational intervention efforts that may extend the controlling effect of the interlock, and data mining research that has uncovered ways to use the stored interlock data record of BAC tests in order to predict high risk drivers; and (6) a discussion of communication barriers and conceptual rigidities that may be preventing the alcohol ignition interlock from taking a more prominent role in the arsenal of tools used to control

  2. Development and some applications of general purpose CAD/CAM/CAE system -IMAGE-

    International Nuclear Information System (INIS)

    Kawasaki, Hisao; Miyazaki, Kotaro; Ando, Hiroaki; Shoji, Toshiaki; Kaneko, Shozo; Umeda, Kazuko; Yoshimura, Atsuhiko; Kogo, Nobuhiko; Sakai, Noriaki

    1985-01-01

    General purpose CAD/CAM/CAE system, named IMAGE (Interactive Modeling Aids for Graphics in Engineering), has been developed. This system is composed of several subsystems. Two modeling types are available, one is a wire frame model and the other is a surface model. CAD subsystems for drawings, piping and preliminary design, CAM subsystems for NC programming/nesting and CAE subsystems for FEM preprocessing are described. Three applications are described. The first application field is the boiler plant design, the second one the nuclear equipment engineering design and the third one the industrial machinery design. (author)

  3. Implementation of a Direct Link between the LHC Beam Interlock System and the LHC Beam Dumping System Re-Triggering Lines

    CERN Document Server

    Gabourin, S; Denz, R; Magnin, N; Uythoven, J; Wollmann, D; Zerlauth, M; Vatansever, V; Bartholdt, M; Bertsche, B; Zeiler, P

    2014-01-01

    To avoid damage of accelerator equipment due to impacting beam, the controlled removal of the LHC beams from the collider rings towards the dump blocks must be guaranteed at all times. When a beam dump is demanded, the Beam Interlock System communicates this request to the Trigger Synchronisation and Distribution System of the LHC Beam Dumping System. Both systems were built according to high reliability standards. To further reduce the risk of incapability to dump the beams in case of correlated failures in the Trigger Synchronisation and Distribution System, a new direct link from the Beam Interlock System to the re-triggering lines of the LHC Beam Dumping System will be implemented for the start-up with beam in 2015. The link represents a diverse redundancy to the current implementation, which should neither significantly increase the risk for so-called asynchronous beam dumps nor compromise machine availability. This paper describes the implementation choices of this link. Furthermore the results of a rel...

  4. Experimental fast reactor 'JOYO' MK-III function test. Interlock test of the primary and secondary cooling system and function test of the remote automatic fuel handling control system

    International Nuclear Information System (INIS)

    Michino, Masanobu; Suzuki, Toshiaki; Aita, Tsuyoshi

    2004-03-01

    This report describes the results of the primary and secondary cooling system interlock test and the fuel handling system function test, which were done as a part of JOYO MK-III function test. The items of the test are: (1) Primary and secondary cooling system interlock test (SKS-106,210). (2) Loss of electric power splay test (SKS-116). (3) In-vessel and ex-vessel automatic fuel transportation test (SKS-501, 502). As the interlock of the primary and secondary cooling system was changed, the interlock test by the reactor scram and the loss of electric power supply was carried out. The function of the remote automatic fuel handling system was confirmed before the handling of the fuel for MK-III core configuration. The results of the test satisfied the required performance, and it was confirmed that operation of the primary and secondary cooling system interlock and operation of the fuel handling system in JOYO MK-III were normal. (author)

  5. AzCam: A Windows-based CCD/CMOS Client/Server Data Acquisition System

    Science.gov (United States)

    Lesser, M.; Parthasarathy, M.

    AzCam is a software package developed to utilize a common architecture for the characterization of CCD and CMOS imagers in both laboratory and astronomical observatory environments. It follows a standard client/server model in which the server runs on a PC under the Microsoft Windows operating system to allow easy integration with the many CMOS imager cameras.

  6. Performance evaluation of Siemens E.Cam® Spect System at Korle ...

    African Journals Online (AJOL)

    Performance evaluation tests on Siemens e.camR Signature Series Single Photon Emission Computed Tomogra-phy (SPECT) System at Korle-Bu Teaching Hospital (Ghana) were conducted for compliance with Manufactur-erfs specifications and usersf requirements. The tests were performed according to National ...

  7. Effectiveness and efficiency of a CAD/CAM orthodontic bracket system.

    Science.gov (United States)

    Brown, Matthew W; Koroluk, Lorne; Ko, Ching-Chang; Zhang, Kai; Chen, Mengqi; Nguyen, Tung

    2015-12-01

    The first straight-wire appliance was introduced over 40 years ago to increase the consistency and efficiency of orthodontic treatment. More recently, computer-aided design and computer-aided manufacturing (CAD/CAM) technology has been used to create individualized orthodontic appliances. The purpose of this study was to investigate the clinical effectiveness and efficiency of CAD/CAM customized orthodontic appliances compared with direct and indirect bonded stock orthodontic brackets. This retrospective study included 3 treatment groups: group 1 patients were direct bonded with self-ligating appliances, group 2 patients were indirect bonded with self-ligating appliances, and group 3 patients were indirect bonded with CAD/CAM self-ligating appliances. Complete pretreatment and posttreatment records were obtained for all patients. The American Board of Orthodontics (ABO) Discrepancy Index was used to evaluate the pretreatment records, and the posttreatment outcomes were analyzed using the ABO Cast-Radiograph Evaluation. All data collection and analysis were completed by 1 evaluator. There were no statistically significant differences in the ABO Discrepancy Index or the ABO Cast-Radiograph Evaluation among the groups. Treatment times for the 3 groups were significantly different; the CAD/CAM group was the shortest at 13.8 ± 3.4 months, compared with 21.9 ± 5.0 and 16.9 ± 4.1 months for the direct bonded and indirect bonded groups, respectively. The number of treatment appointments for the CAD/CAM group was significantly fewer than for the direct bonded group. The CAD/CAM orthodontic bracket system evaluated in this study was as effective in treatment outcome measures as were standard brackets bonded both directly and indirectly. The CAD/CAM appliance was more efficient in regard to treatment duration, although the decrease in total archwire appointments was minimal. Further investigation is needed to better quantify the clinical benefits of CAD/CAM orthodontic

  8. Beam-limiting and radiation-limiting interlocks

    International Nuclear Information System (INIS)

    Macek, R.J.

    1996-01-01

    This paper reviews several aspects of beam-limiting and radiation- limiting interlocks used for personnel protection at high-intensity accelerators. It is based heavily on the experience at the Los Alamos Neutron Science Center (LANSCE) where instrumentation-based protection is used extensively. Topics include the need for ''active'' protection systems, system requirements, design criteria, and means of achieving and assessing acceptable reliability. The experience with several specific devices (ion chamber-based beam loss interlock, beam current limiter interlock, and neutron radiation interlock) designed and/or deployed to these requirements and criteria is evaluated

  9. Beam-limiting and radiation-limiting interlocks

    Energy Technology Data Exchange (ETDEWEB)

    Macek, R.J.

    1996-04-01

    This paper reviews several aspects of beam-limiting and radiation- limiting interlocks used for personnel protection at high-intensity accelerators. It is based heavily on the experience at the Los Alamos Neutron Science Center (LANSCE) where instrumentation-based protection is used extensively. Topics include the need for ``active`` protection systems, system requirements, design criteria, and means of achieving and assessing acceptable reliability. The experience with several specific devices (ion chamber-based beam loss interlock, beam current limiter interlock, and neutron radiation interlock) designed and/or deployed to these requirements and criteria is evaluated.

  10. APPLICATION OF 3D DIGITAL SCANNING AND CAD/CAM SYSTEMS FOR ZIRCONIA INDIRECT RESTORATIONS

    Directory of Open Access Journals (Sweden)

    Mariela Tsanova

    2016-09-01

    Full Text Available Object: To study the CAD/CAM systems’ possibilities for manufacturing Zirconia indirect restorations for restoring vital, vastly devastated teeth. Material and methods: Five patients with vital, heavily destroyed molars were included in the clinical study. The teeth were prepared according to requirements for Zirconia restorations. The impressions were taken with 3D intraoral scanner. The acquired data is transmitted electronically for designing the future restoration by the CAD software. After designing, the restoration is milled by the CAM module and sintered, according to a specially projected programme in accordance with the manufacturing demands. After clinical check-up, the restorations are glazed, air-blasted and cemented. Results: Setting up an individual protocol for working with CAD/CAM systems for restoring vital, severely devastated teeth with Zirconia indirect restorations. A research is made on 3D digital scanning, occlusal and proximal modeling, virtual articulation, analyzing the incline of the cavity walls, the thickness of the restoration and the possibilities for restoring the anatomy of the tooth according to patient’s individual characteristics of the teeth’s arch. Conclusion: The scanning and design process should be evaluated with the same quality control as when using traditional methods. The CAD software requires excellent preparation of the tooth cavity and digital scanning. This is the reason why these systems require a thorough understanding of CAD/CAM calibration and parameters of the product to be clinically acceptable. Once understood, CAD/CAM dentistry can create detailed and accurate restorations that function and perform with great success and longevity.

  11. Real time software for the control and monitoring of DIII-D system interlocks

    International Nuclear Information System (INIS)

    Broesch, J.D.; Penaflor, B.G.; Coon, R.M.; Harris, J.J.; Scoville, J.T.

    1996-10-01

    This paper describes the real time, multi-tasking, multi-user software and communications of the E-Power Supply System Integrated Controller (EPSSIC) for the DIII-D tokamak. EPSSIC performs the DIII-D system wide go/no-go determination for the plasma sequencing. This paper discusses the data module handling, task work load balancing, and communications requirements. Operational experience with the new EPSSIC and recent improvements to this system are also described

  12. The National Shipbuilding Research Program. Evaluation of Shipbuilding CAD/CAM Systems (Phase I)

    Science.gov (United States)

    1996-10-14

    Industries Norddeutsche Itiormations Systems GmbH Odense Steel Shipyard Sener Ingenieria y Sistemas SMK Ingenieurburo Verolrne Scheepswerf Heusden b.v...specifics of technology, but it is not possible to de - couple technology from the other factors listed above. Specifically, we have observed that... Sistemas , S.A. Fernando Alonso, Manager G-4 1.0 2.0 3.0 4.0 5.0 Evaluation of Shipbuilding CAD/CAM/CIM System Implementations Table of Contents

  13. Gamma Ray Imaging System (GRIS) GammaCam trademark. Final report, January 3, 1994 - May 31, 1996

    International Nuclear Information System (INIS)

    1996-01-01

    This report describes the activities undertaken during the development of the Gamma Ray Imaging System (GRIS) program now referred to as the GammaCam trademark. The purpose of this program is to develop a 2-dimensional imaging system for gamma-ray energy scenes that may be present in nuclear power plants. The report summarizes the overall accomplishments of the program and the most recent GammaCam measurements made at LANL and Estonia. The GammaCam is currently available for sale from AIL Systems as an off-the-shelf instrument

  14. Gamma Ray Imaging System (GRIS) GammaCam{trademark}. Final report, January 3, 1994--May 31, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report describes the activities undertaken during the development of the Gamma Ray Imaging System (GRIS) program now referred to as the GammaCam{trademark}. The purpose of this program is to develop a 2-dimensional imaging system for gamma-ray energy scenes that may be present in nuclear power plants. The report summarizes the overall accomplishments of the program and the most recent GammaCam measurements made at LANL and Estonia. The GammaCam is currently available for sale from AIL Systems as an off-the-shelf instrument.

  15. Generic FPGA-Based Platform for Distributed IO in Proton Therapy Patient Safety Interlock System

    Science.gov (United States)

    Eichin, Michael; Carmona, Pablo Fernandez; Johansen, Ernst; Grossmann, Martin; Mayor, Alexandre; Erhardt, Daniel; Gomperts, Alexander; Regele, Harald; Bula, Christian; Sidler, Christof

    2017-06-01

    At the Paul Scherrer Institute (PSI) in Switzerland, cancer patients are treated with protons. Proton therapy at PSI has a long history and started in the 1980s. More than 30 years later, a new gantry has recently been installed in the existing facility. This new machine has been delivered by an industry partner. A big challenge is the integration of the vendor's safety system into the existing PSI environment. Different interface standards and the complexity of the system made it necessary to find a technical solution connecting an industry system to the existing PSI infrastructure. A novel very flexible distributed IO system based on field-programmable gate array (FPGA) technology was developed, supporting many different IO interface standards and high-speed communication links connecting the device to a PSI standard versa module eurocard-bus input output controller. This paper summarizes the features of the hardware technology, the FPGA framework with its high-speed communication link protocol, and presents our first measurement results.

  16. The data acquisition and interlock system for Tore Supra infrared imaging

    International Nuclear Information System (INIS)

    Moulin, D.; Balorin, C.; Buravand, Y.; Caulier, G.; Ducobu, L.; Guilhem, D.; Jouve, M.; Roche, H.

    2003-01-01

    The data acquisition for the infrared measurement system on Tore-Supra is a key element in ensuring the supervision of the new actively-cooled plasma facing components of the CIEL project. It will allow us to follow the thermal evolution of components of Tore-Supra, in particular the toroidal pumped limiter (LPT) (360 deg.-15 m long) and the five additional heating launchers. When fully installed, the infrared measurement system will be composed of 12 digital 16-bit infrared cameras. They cover a 100-1200 deg.C temperature range and each picture has a definition of 320x240 pixels with a 20 ms time resolution. The objectives of the data acquisition system is real-time recording and analysis of each view element for further post-pulse analysis in order to understand the physics phenomenon and ensure the supervision of the plasma facing components and also to be part of the global feedback control system of Tore Supra

  17. Machine Protection and Interlock Systems for Circular Machines - Example for LHC

    CERN Document Server

    Schmidt, R.

    2016-01-01

    This paper introduces the protection of circular particle accelerators from accidental beam losses. Already the energy stored in the beams for accelerators such as the TEVATRON at Fermilab and Super Proton Synchrotron (SPS) at CERN could cause serious damage in case of uncontrolled beam loss. With the CERN Large Hadron Collider (LHC), the energy stored in particle beams has reached a value two orders of magnitude above previous accelerators and poses new threats with respect to hazards from the energy stored in the particle beams. A single accident damaging vital parts of the accelerator could interrupt operation for years. Protection of equipment from beam accidents is mandatory. Designing a machine protection system requires an excellent understanding of accelerator physics and operation to anticipate possible failures that could lead to damage. Machine protection includes beam and equipment monitoring, a system to safely stop beam operation (e.g. extraction of the beam towards a dedicated beam dump block o...

  18. Investigation of roughing machining simulation by using visual basic programming in NX CAM system

    Science.gov (United States)

    Hafiz Mohamad, Mohamad; Nafis Osman Zahid, Muhammed

    2018-03-01

    This paper outlines a simulation study to investigate the characteristic of roughing machining simulation in 4th axis milling processes by utilizing visual basic programming in NX CAM systems. The selection and optimization of cutting orientation in rough milling operation is critical in 4th axis machining. The main purpose of roughing operation is to approximately shape the machined parts into finished form by removing the bulk of material from workpieces. In this paper, the simulations are executed by manipulating a set of different cutting orientation to generate estimated volume removed from the machine parts. The cutting orientation with high volume removal is denoted as an optimum value and chosen to execute a roughing operation. In order to run the simulation, customized software is developed to assist the routines. Operations build-up instructions in NX CAM interface are translated into programming codes via advanced tool available in the Visual Basic Studio. The codes is customized and equipped with decision making tools to run and control the simulations. It permits the integration with any independent program files to execute specific operations. This paper aims to discuss about the simulation program and identifies optimum cutting orientations for roughing processes. The output of this study will broaden up the simulation routines performed in NX CAM systems.

  19. Radiation safety interlocks at the NSLS

    International Nuclear Information System (INIS)

    Dickinson, T.

    1985-07-01

    The function of the NSLS interlock systems is to insure that no one is in an area where there is hazardous radiation, and to turn off the radiation source if a person somehow gains access to such an area. The interlock systems for the high hazard areas meet the following design requirements: (1) The system is redundant, that is no single failure can render the system unsafe. This is done by providing 2 independent systems or circuits; (2) In so far as possible, the two circuits are physically different. This minimizes the possibility of related coincident failures; (3) The design is fail safe. This means that the most likely failure modes leave the system in a safe condition. For example, the following failures are safe: Loss of power in any part of the system, any combination of shorts to ground, and any combination of open circuits; and (4) The interlock system must be testable. Redundancy sometimes makes testing difficult, but testing schemes must be worked out, since an untested interlock is undependable

  20. DeepSurveyCam--A Deep Ocean Optical Mapping System.

    Science.gov (United States)

    Kwasnitschka, Tom; Köser, Kevin; Sticklus, Jan; Rothenbeck, Marcel; Weiß, Tim; Wenzlaff, Emanuel; Schoening, Timm; Triebe, Lars; Steinführer, Anja; Devey, Colin; Greinert, Jens

    2016-01-28

    Underwater photogrammetry and in particular systematic visual surveys of the deep sea are by far less developed than similar techniques on land or in space. The main challenges are the rough conditions with extremely high pressure, the accessibility of target areas (container and ship deployment of robust sensors, then diving for hours to the ocean floor), and the limitations of localization technologies (no GPS). The absence of natural light complicates energy budget considerations for deep diving flash-equipped drones. Refraction effects influence geometric image formation considerations with respect to field of view and focus, while attenuation and scattering degrade the radiometric image quality and limit the effective visibility. As an improvement on the stated issues, we present an AUV-based optical system intended for autonomous visual mapping of large areas of the seafloor (square kilometers) in up to 6000 m water depth. We compare it to existing systems and discuss tradeoffs such as resolution vs. mapped area and show results from a recent deployment with 90,000 mapped square meters of deep ocean floor.

  1. 49 CFR 236.312 - Movable bridge, interlocking of signal appliances with bridge devices.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Movable bridge, interlocking of signal appliances with bridge devices. 236.312 Section 236.312 Transportation Other Regulations Relating to... SYSTEMS, DEVICES, AND APPLIANCES Interlocking Standards § 236.312 Movable bridge, interlocking of signal...

  2. A comparative evaluation of implant supported zirconia framework gap of two CAD/CAM systems

    Directory of Open Access Journals (Sweden)

    Narges Ameri

    2016-11-01

    computer-aided manufacturing (CAM systems (AmannGirrbach and Zirkonzahn. Materials and Methods: The master model of 3-unit FDP was made of two implant abutments (AmannGirrbach and Zirkonzahn from canine to second premolar. Twelve frameworks were manufactured using each fabricating system from semi-sintered zirconia blanks, which had to be sintered for final density after milling. After manufacturing, the absolute marginal discrepancy in each abutment were determined by means of Video Measurement System (VMS. The data were analyzed, using independent and paired t test (P=0.05. Results: For the premolar abutment, the absolute marginal discrepancy of frameworks fabricated by AmannGirrbach system was significantly greater than those of the other system (P=0.005. There was no significant difference between the marginal discrepancy of canine and premolar abutments (P>0.05. Conclusion: Within the limitations of this study, it could be concluded that the marginal fit of zirconia FDPs was significantly dependent on the CAD/CAM system used, but the abutment size was not an effective factor.

  3. Clinical outcomes of three different crown systems with CAD/CAM technology.

    Science.gov (United States)

    Batson, Emily R; Cooper, Lyndon F; Duqum, Ibrahim; Mendonça, Gustavo

    2014-10-01

    Computer-aided design and computer-aided manufacturing (CAD/CAM) generated restorations are gaining popularity. However, limited clinical evidence is available for single-unit posterior CAD/CAM restorations fabricated with established and newer crown materials. The purpose of this clinical study was to assess the restoration quality of and gingival response to CAD/CAM fabricated posterior single-tooth restorations with different processing technologies. Twenty-two individuals in need of posterior complete coverage crowns were recruited under an institutional review board approved protocol. Teeth were randomized to 1 of 3 groups: metal ceramic, lithium disilicate, and monolithic zirconia. An unprepared or minimally restored tooth on the contralateral side was chosen as a control tooth for gingival measurements with each participant. Teeth were prepared and scanned intraorally by 1 of 3 experienced practitioners. A total of 32 restorations were digitally designed and fabricated with either milling technology or rapid-prototype printing and casting with conventional porcelain application. Restorations were evaluated with modified United States Public Health Service criteria for contour, marginal adaptation, occlusion, and shade. Gingival crevicular fluid volume and bleeding on probing were recorded preoperatively, at 1-month and 6-month postcementation visits. Polyvinyl siloxane impressions were made of the buccal margin of cemented restorations and evaluated with microcomputed tomography to assess marginal adaptation (horizontal discrepancy). The Mantel Haenszel row mean score was used to assess whether the crown systems differed with respect to the modified United States Public Health Service criteria. Linear mixed models were used to assess whether the average gingival volumes were affected by the explanatory variables (crown system, tooth status [treated vs control], or visit). A generalized estimating equation approach was used to assess whether bleeding on

  4. Evaluation of Visunex Medical's PanoCam(TM) LT and PanoCam(TM) Pro wide-field imaging systems for the screening of ROP in newborn infants.

    Science.gov (United States)

    Wood, Edward H; Moshfeghi, Andrew A; Nudleman, Eric D; Moshfeghi, Darius M

    2016-08-01

    Retinopathy of Prematurity (ROP) is a leading cause of childhood blindness. The incidence of ROP is rising, placing greater demands on the healthcare providers that serve these patients and their families. Telemedicine remote digital fundus imaging (TM-RDFI) plays a pivotal role in ROP management, and has allowed for the expansion of ROP care into previously underserved areas. A broad literature review through the pubmed index was undertaken with the goal of summarizing the current state of ROP and guidelines for its screening . Furthermore, all currently used telemedicine remote digital fundus imaging devices were analyzed both via the literature and the companies' websites/brochures. Finally, the PanoCam LT™ and PanoCam™ Pro created by Visunex Medical were analyzed via the company website/brochures. Expert commentary: The PanoCam LT™ and PanoCam™ Pro have recently been approved for use within the USA and CE marked for international commercialization in European Union and other countries requiring CE mark. These wide-field imaging systems have the intended use of ophthalmic imaging of all newborn babies and meet the requirements for ROP screening, thereby serving as competition within the ROP screening market previously dominated by one camera imaging system.

  5. The on-site quality-assurance system for Hyper Suprime-Cam: OSQAH

    Science.gov (United States)

    Furusawa, Hisanori; Koike, Michitaro; Takata, Tadafumi; Okura, Yuki; Miyatake, Hironao; Lupton, Robert H.; Bickerton, Steven; Price, Paul A.; Bosch, James; Yasuda, Naoki; Mineo, Sogo; Yamada, Yoshihiko; Miyazaki, Satoshi; Nakata, Fumiaki; Koshida, Shintaro; Komiyama, Yutaka; Utsumi, Yousuke; Kawanomoto, Satoshi; Jeschke, Eric; Noumaru, Junichi; Schubert, Kiaina; Iwata, Ikuru; Finet, Francois; Fujiyoshi, Takuya; Tajitsu, Akito; Terai, Tsuyoshi; Lee, Chien-Hsiu

    2018-01-01

    We have developed an automated quick data analysis system for data quality assurance (QA) for Hyper Suprime-Cam (HSC). The system was commissioned in 2012-2014, and has been offered for general observations, including the HSC Subaru Strategic Program, since 2014 March. The system provides observers with data quality information, such as seeing, sky background level, and sky transparency, based on quick analysis as data are acquired. Quick-look images and validation of image focus are also provided through an interactive web application. The system is responsible for the automatic extraction of QA information from acquired raw data into a database, to assist with observation planning, assess progress of all observing programs, and monitor long-term efficiency variations of the instrument and telescope. Enhancements of the system are being planned to facilitate final data analysis, to improve the HSC archive, and to provide legacy products for astronomical communities.

  6. Repair bond strength of resin composite to a novel CAD/CAM hybrid ceramic using different repair systems.

    Science.gov (United States)

    Elsaka, Shaymaa E

    2015-01-01

    This study evaluated the repair bond strength of a nanohybrid resin composite to a novel CAD/CAM hybrid ceramic based on four intraoral ceramic repair systems. Vita Enamic (VE) CAD/CAM hybrid ceramic was used in this study. Specimens were divided into five test groups according to the repair method performed on the ceramic surface: Gr C (No treatment; control); Gr CZ (Cimara Zircon); Gr PR (Porcelain Repair); Gr CR (Clearfil Repair); and Gr CS (CoJet system). Nanohybrid resin composite (GrandioSO) was packed onto treated ceramic surfaces for adhesion testing using microtensile bond strength test. Debonded specimens were examined with a stereomicroscope and SEM to determine the fracture mode. Data were analyzed using ANOVA and Tukey's HSD test. PR and CZ repair systems significantly enhanced the bond strength of nanohybrid resin composite to VE CAD/CAM hybrid ceramic when compared with the other tested repair systems.

  7. Some aspects of operational reliability of the JET central interlock and safety system (CISS) in the period March 1984 to December 1986

    International Nuclear Information System (INIS)

    Montfoort, Joop van.

    1987-01-01

    The Central Interlock and Safety System (CISS) provides basic safety functions for the JET plant. It monitors the status of emergency push buttons, access doors and plant equipment and takes corrective shutdown actions in the case that plant conditions are not compatible with safe operation. CISS consists of a hierarchical network of PLCs (programmable logic controllers) paralleling the CODAS architecture. It has been successfully in operation since June 1983 and has intervened many times and halted operation to protect JET from (further) damage or personnel against danger. The note will analyse genuine CISS failures only, and as will be shown, these failures are all due to malfunctioning of PLC hardware. All CISS failures have failed-safe and resulted in the expected shutdown action. Hence CISS failures have never resulted in a dangerous situation but they have restricted operational availability of JET. (author)

  8. Colour parameters and shade correspondence of CAD-CAM ceramic systems.

    Science.gov (United States)

    Della Bona, Alvaro; Pecho, Oscar E; Ghinea, Razvan; Cardona, Juan C; Pérez, María M

    2015-06-01

    To evaluate colour differences between (1) CAD-CAM ceramic systems considering shades A1, A2 and A3 and the corresponding nominal shade of VC (Vita Classical shade guide) and (2) shades A1-A2, A2-A3 and A1, A2 and A3 within the same ceramic system. Samples of shades A1, A2 and A3 were fabricated (n=5) from CAD-CAM ceramic blocks (IPS e.max(®) CAD LT and HT, IPS Empress(®) CAD LT and HT, Paradigm™ C, and VITABLOCS(®) Mark II) and polished to 1.0±0.01mm in thickness. Spectral reflectance and colour coordinates were measured using a spectroradiometer inside a viewing booth using the CIE D65 illuminant and the d/0° geometry. Spectral reflectance curves were compared using VAF coefficient and were statistically analyzed using Kruskal-Wallis and the Mann-Whitney U test (α=0.05). Colour coordinates were statistically analyzed using one-way ANOVA, Tukey's test with Bonferroni correction (α=0.001). All colour differences (ΔEab(*) and ΔE00) were analyzed through comparisons with the PT - perceptibility and AT - acceptability thresholds for dental ceramics. ΔE between ceramic systems and its corresponding shade ranged from 6.32 to 13.42 (ΔEab(*)) and 4.48 to 9.30 (ΔE00). ΔE between shades A1-A2, A2-A3 and A1, A2 and A3 ranged, respectively, 1.93-4.82, 1.22-5.59 and 3.63-8.84 (ΔEab(*)); 1.54-3.87, 1.03-3.90 and 2.95-6.51 (ΔE00). Considering the corresponding nominal shade from VC, none of the ceramic systems showed colour differences below the AT. In addition, some ceramic systems showed colour differences below AT (shades A1-A2 and A2-A3) and below PT (shades A2-A3). Careful adjustments should be made to the final shade of CAD-CAM ceramic restorations to reach a clinically acceptable shade match. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. FRACTURE SHAFT HUMERUS: INTERLOCKING

    Directory of Open Access Journals (Sweden)

    Deepak Kaladagi

    2014-12-01

    Full Text Available BACKGROUND: The incidence of humeral fracture has significantly increased during the present years due to the population growth and road traffic, domestic, industrial, automobile accidents & disasters like tsunami, earthquakes, head-on collisions, polytrauma etc. In order to achieve a stable fixation followed by early mobilization, numerous surgical implants have been devised. PURPOSE: The purpose of this study is to analyze the results of intramedullary fixation of proximal 2/3rd humeral shaft fractures using an unreamed interlocking intramedullary nail. INTRODUCTION: In 40 skeletally matured patients with fracture shaft of humerus admitted in our hospital, we used unreamed antegrade interlocking nails. MATERIAL: We carried out a prospective analysis of 40 patients randomly selected between 2001 to 2014 who were operated at JNMC Belgaum, MMC Mysore & Navodaya Medical College, Raichur. All cases were either RTAs, Domestic, Industrial, automobile accidents & also other modes of injury. METHOD: Routine investigations with pre-anaesthetic check-up & good quality X-rays of both sides of humerus was taken. Time of surgery ranged from 5-10 days from the time of admission. Only upper 1/3rd & middle 1/3rd humeral shaft fractures were included in the study. In all the cases antegrade locked unreamed humeral nails were inserted under C-arm. Patient was placed in supine position & the shoulder was kept elevated by placing a sandbag under the scapula. In all patients incision taken from tip of acromion to 3cm over deltoid longitudinally. Postoperatively sling applied with wrist & shoulder movements started after 24 hours. All the patients ranged between the age of 21-50 years. RESULTS: Total 40 patients were operated. Maximum fracture site were in the middle third- 76%, 14% upper 1/3rd. All 40 patients achieved union. The average time of union was 8-10 weeks. All patients regained full range of movements except in few cases, where there was shoulder

  10. Failure analysis of a repairable system: The case study of a cam-driven reciprocating pump

    Science.gov (United States)

    Dudenhoeffer, Donald D.

    1994-09-01

    This thesis supplies a statistical and economic tool for analysis of the failure characteristics of one typical piece of equipment under evaluation: a cam-driven reciprocating pump used in the submarine's distillation system. Comprehensive statistical techniques and parametric modeling are employed to identify and quantify pump failure characteristics. Specific areas of attention include: the derivation of an optimal maximum replacement interval based on costs, an evaluation of the mission reliability for the pump as a function of pump age, and a calculation of the expected times between failures. The purpose of this analysis is to evaluate current maintenance practices of time-based replacement and examine the consequences of different replacement intervals in terms of costs and mission reliability. Tradeoffs exist between cost savings and system reliability that must be fully understood prior to making any policy decisions.

  11. Laboratory Performance of Universal Adhesive Systems for Luting CAD/CAM Restorative Materials.

    Science.gov (United States)

    Siqueira, Fabiana; Cardenas, Andres Millan; Gutierrez, Mario Felipe; Malaquias, Pâmela; Hass, Viviane; Reis, Alessandra; Loguercio, Alessandro D; Perdigão, Jorge

    To evaluate the microshear bond strength (μSBS) of several universal adhesive systems applied on five different indirect restorative materials. Five CAD/CAM materials were selected: 1) indirect resin composite (LAV); 2) feldspathic glass ceramic (VTR); 3) leucite-reinforced glass-ceramic (EMP); 4) lithium disilicate ceramic (EMX); 5) yttrium-stabilized zirconium dioxide (CZI). For each material, 15 blocks were cut into 4 rectangular sections (6 × 6 × 6 mm) (n = 60 per group), and processed as recommended by the respective manufacturer. For each indirect material, the following adhesive systems were applied according to the respective manufacturer's instructions: 1) AdheSE Universal [ADU]; 2) All-Bond Universal (ABU); 3) Ambar Universal (AMB); 4) Clearfil Universal (CFU); 5) Futurabond U (FBU); 6) One Coat 7 Universal (OCU); 7) Peak Universal Bond (PUB); 8) Prime&Bond Elect (PBE); 9) Scotchbond Universal Adhesive (SBU); 10) Xeno Select (XEN, negative control). After the application of the adhesive system, cylinder-shaped transparent matrices were filled with a dual-curing resin cement (NX3) and light cured. Specimens were stored in water (37°C for 24 h) and tested in shear mode at 1.0 mm/min (mSBS). The failure pattern and μSBS were statistically evaluated (a = 0.05). LAV, VTR, and EMP showed a greater number of cohesive fractures than EMX and CZI (p < 0.0001). PUB was the only adhesive for which the mean μSBS reached the highest ranking of statistical significance for all five substrates. When each adhesive was compared across the five substrates, 8 out of 10 (ADU, ABU, AMB, CFU, OCU, PUB, PBE, and SBU) reached the statistically highest mean μSBS when applied on CZI. The specific chemical composition of universal adhesives was not the decisive factor in the bond strength values measured for different CAD/CAM indirect materials. There was a wide variability in mean μSBS when different universal adhesives were applied to the several CAD/CAM indirect materials

  12. CAM and NK Cells

    Directory of Open Access Journals (Sweden)

    Kazuyoshi Takeda

    2004-01-01

    Full Text Available It is believed that tumor development, outgrowth and metastasis are under the surveillance of the immune system. Although both innate and acquired immune systems play roles, innate immunity is the spearhead against tumors. Recent studies have revealed the critical role of natural killer (NK cells in immune surveillance and that NK cell activity is considerably influenced by various agents, such as environmental factors, stress, foods and drugs. Some of these NK cell stimulants have been used in complementary and alternative medicine (CAM since ancient times. Therefore, the value of CAM should be re-evaluated from this point of view. In this review, we overview the intimate correlation between NK cell functions and CAM agents, and discuss possible underlying mechanisms mediating this. In particular, neuro-immune crosstalk and receptors for CAM agents are the most important and interesting candidates for such mechanisms.

  13. A G-function-based reliability-based design methodology applied to a cam roller system

    International Nuclear Information System (INIS)

    Wang, W.; Sui, P.; Wu, Y.T.

    1996-01-01

    Conventional reliability-based design optimization methods treats the reliability function as an ordinary function and applies existing mathematical programming techniques to solve the design problem. As a result, the conventional approach requires nested loops with respect to g-function, and is very time consuming. A new reliability-based design method is proposed in this paper that deals with the g-function directly instead of the reliability function. This approach has the potential of significantly reducing the number of calls for g-function calculations since it requires only one full reliability analysis in a design iteration. A cam roller system in a typical high pressure fuel injection diesel engine is designed using both the proposed and the conventional approach. The proposed method is much more efficient for this application

  14. Beam Interlocks for LHC and SPS

    CERN Document Server

    Dinius, A; Gimeno-Vicente, J; Nouchi, P; Puccio, B; Schmidt, R; Wenninger, J

    2003-01-01

    The Large Hadron Collider at CERN (LHC) will operate at 7 TeV/c with a luminosity of 10 cms. This requires two beams with about 3^10 protons/beam, corresponding to a stored energy of about 350 MJ, sufficient to heat and melt 500 kg of copper. Protection of equipment from damage in case of uncontrolled beam losses is challenging. Injection of the beam from the SPS to the LHC could already damage equipment and is only permitted when all LHC systems are correctly prepared. In case of an uncontrolled loss of the circulating LHC beams, it is required to extract the beams into a specially designed target as soon as possible. Beam loss monitors and equipment for hardware surveillance are distributed around the 26 km long accelerator. In case of failures or beam losses, the beam interlock system is informed and sends a dump request to the beam dumping system. The beam interlock system also inhibits injection when the LHC is not ready for beam. In this paper the requirements for the beam interlock system are discussed...

  15. Agave as a model CAM crop system for a warming and drying world.

    Science.gov (United States)

    Stewart, J Ryan

    2015-01-01

    As climate change leads to drier and warmer conditions in semi-arid regions, growing resource-intensive C3 and C4 crops will become more challenging. Such crops will be subjected to increased frequency and intensity of drought and heat stress. However, agaves, even more than pineapple (Ananas comosus) and prickly pear (Opuntia ficus-indica and related species), typify highly productive plants that will respond favorably to global warming, both in natural and cultivated settings. With nearly 200 species spread throughout the U.S., Mexico, and Central America, agaves have evolved traits, including crassulacean acid metabolism (CAM), that allow them to survive extreme heat and drought. Agaves have been used as sources of food, beverage, and fiber by societies for hundreds of years. The varied uses of Agave, combined with its unique adaptations to environmental stress, warrant its consideration as a model CAM crop. Besides the damaging cycles of surplus and shortage that have long beset the tequila industry, the relatively long maturation cycle of Agave, its monocarpic flowering habit, and unique morphology comprise the biggest barriers to its widespread use as a crop suitable for mechanized production. Despite these challenges, agaves exhibit potential as crops since they can be grown on marginal lands, but with more resource input than is widely assumed. If these constraints can be reconciled, Agave shows considerable promise as an alternative source for food, alternative sweeteners, and even bioenergy. And despite the many unknowns regarding agaves, they provide a means to resolve disparities in resource availability and needs between natural and human systems in semi-arid regions.

  16. Agave as a model CAM crop system for a warming and drying world

    Directory of Open Access Journals (Sweden)

    J. Ryan eStewart

    2015-09-01

    Full Text Available As climate change leads to drier and warmer conditions in semi-arid regions, growing resource-intensive C3 and C4 crops will become more challenging. Such crops will be subjected to increased frequency and intensity of drought and heat stress. However, agaves, even more than pineapple (Ananas comosus and prickly pear (Opuntia ficus-indica and related species, typify highly productive plants that will respond favorably to global warming, both in natural and cultivated settings. With nearly 200 species spread throughout the U.S., Mexico, and Central America, agaves have evolved traits, including crassulacean acid metabolism (CAM, that allow them to survive extreme heat and drought. Agaves have been used as sources of food, beverage, and fiber by societies for hundreds of years. The varied uses of Agave, combined with its unique adaptations to environmental stress, warrant its consideration as a model CAM crop. Besides the damaging cycles of surplus and shortage that have long beset the tequila industry, the relatively long maturation cycle of Agave, its monocarpic flowering habit, and unique morphology comprise the biggest barriers to its widespread use as a crop suitable for mechanized production. Despite these challenges, agaves exhibit potential as crops since they can be grown on marginal lands, but with more resource input than is widely assumed. If these constraints can be reconciled, Agave shows considerable promise as an alternative source for food, alternative sweeteners, and even bioenergy. And despite the many unknowns regarding agaves, they provide a means to resolve disparities between natural and human systems in semi-arid regions.

  17. Interlocking Nailing Versus Interlocking Plating in Intra-articular Calcaneal Fractures: A Biomechanical Study.

    Science.gov (United States)

    Reinhardt, Sophia; Martin, Heiner; Ulmar, Benjamin; Döbele, Stefan; Zwipp, Hans; Rammelt, Stefan; Richter, Martinus; Pompach, Martin; Mittlmeier, Thomas

    2016-08-01

    Open reduction and internal fixation with a plate is deemed to represent the gold standard of surgical treatment for displaced intra-articular calcaneal fractures. Standard plate fixation is usually placed through an extended lateral approach with high risk for wound complications. Minimally invasive techniques might avoid wound complications but provide limited construct stability. Therefore, 2 different types of locking nails were developed to allow for minimally invasive technique with sufficient stability. The aim of this study was to quantify primary stability of minimally invasive calcaneal interlocking nail systems in comparison to a variable-angle interlocking plate. After quantitative CT analysis, a standardized Sanders type IIB fracture model was created in 21 fresh-frozen cadavers. For osteosynthesis, 2 different interlocking nail systems (C-Nail; Medin, Nov. Město n. Moravě, Czech Republic; Calcanail; FH Orthopedics SAS; Heimsbrunn, France) as well as a polyaxial interlocking plate (Rimbus; Intercus GmbH; Rudolstadt, Germany) were used. Biomechanical testing consisted of a dynamic load sequence (preload 20 N, 1000 N up to 2500 N, stepwise increase of 100 N every 100 cycles, 0.5 mm/s) and a load to failure sequence (max. load 5000 N, 0.5 mm/s). Interfragmentary movement was detected via a 3-D optical measurement system. Boehler angle was measured after osteosynthesis and after failure occurred. No significant difference regarding load to failure, stiffness, Boehler angle, or interfragmentary motion was found between the different fixation systems. A significant difference was found with the dynamic failure testing sequence where 87.5% of the Calcanail implants failed in contrast to 14% of the C-Nail group (P plate. The highest load to failure was observed for the C-Nail. Boehler angle showed physiologic range with all implants before and after the biomechanical tests. Both minimally invasive interlocking nail systems displayed a high primary stability

  18. In vitro evaluation of marginal discrepancy of monolithic zirconia restorations fabricated with different CAD-CAM systems.

    Science.gov (United States)

    Hamza, Tamer A; Sherif, Rana M

    2017-06-01

    Dental laboratories use different computer-aided design and computer-aided manufacturing (CAD-CAM) systems to fabricate fixed prostheses; however, limited evidence is available concerning which system provides the best marginal discrepancy. The purpose of this in vitro study was to evaluate the marginal fit of 5 different monolithic zirconia restorations milled with different CAD-CAM systems. Thirty monolithic zirconia crowns were fabricated on a custom-designed stainless steel die and were divided into 5 groups according to the type of monolithic zirconia crown and the CAD-CAM system used: group TZ, milled with an MCXL milling machine; group CZ, translucent zirconia milled with a motion milling machine; group ZZ, zirconia milled with a dental milling unit; group PZ, translucent zirconia milled with a zirconia milling unit; and group BZ, solid zirconia milled using an S1 VHF milling machine. The marginal fit was measured with a binocular microscope at an original magnification of ×100. The results were tabulated and statistically analyzed with 1-way ANOVA and post hoc surface range test, and pairwise multiple comparisons were made using Bonferroni correction (α=.05). The type of CAD-CAM used affected the marginal fit of the monolithic restoration. The mean (±SD) highest marginal discrepancy was recorded in group TZI at 39.3 ±2.3 μm, while the least mean marginal discrepancy was recorded in group IZ (22.8 ±8.9 μm). The Bonferroni post hoc test showed that group TZI was significantly different from all other groups tested (Pzirconia restorations with clinically acceptable marginal discrepancies; however, the CAD-CAM system with the 5-axis milling unit produced the best marginal fit. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  19. Comparison of the fit accuracy of zirconia-based prostheses generated by two CAD/CAM systems

    Science.gov (United States)

    2016-01-01

    PURPOSE The purposes of this study are to evaluate the internal and marginal adaptation of two widely used CAD/CAM systems and to study the effect of porcelain press veneering process on the prosthesis adaptation. MATERIALS AND METHODS Molar of a lower jaw typodont resin model was prepared by adjusting a 1.0 mm circumferential chamfer, an occlusal reduction of 2.0 mm, and a 5° convergence angle and was duplicated as an abrasion-resistant master die. The monolithic crowns and copings were fabricated with two different CAD/CAM system-Ceramil and Zirkonzahn systems. Two kinds of non-destructive analysis methods are used in this study. First, weight technique was used to determine the overall fitting accuracy. And, to evaluate internal and marginal fit of specific part, replica technique procedures were performed. RESULTS The silicone weight for the cement space of monolithic crowns and copings manufactured with Ceramil system was significantly higher than that from Zirkonzahn system. This gap might cause the differences in the silicone weight because the prostheses were manufactured according to the recommendation of each system. Marginal discrepancies of copings made with Ceramil system were between 106 and 117 µm and those from Zirkonzahn system were between 111 and 115 µm. Marginal discrepancies of copings made with Ceramil system were between 101 and 131 µm and those from Zirkonzahn system were between 116 and 131 µm. CONCLUSION Marginal discrepancy was relatively lower in Ceramil system and internal gap was smaller in Zirkonzahn system. There were significant differences in the internal gap of monolithic crown and coping among the 2 CAD/CAM systems. Marginal discrepancy produced from the 2 CAD/CAM systems were within a reported clinically acceptable range of marginal discrepancy. PMID:28018561

  20. The ChemCam Instrument Suite on the Mars Science Laboratory (MSL) Rover: Body Unit and Combined System Tests

    International Nuclear Information System (INIS)

    Wiens, Roger C.; Barraclough, Bruce; Barkley, Walter C.; Bender, Steve; Bernardin, John; Bultman, Nathan; Clanton, Robert C.; Clegg, Samuel; Delapp, Dorothea; Dingler, Robert; Enemark, Don; Flores, Mike; Hale, Thomas; Lanza, Nina; Lasue, Jeremie; Latino, Joseph; Little, Cynthia; Morrison, Leland; Nelson, Tony; Romero, Frank; Salazar, Steven; Stiglich, Ralph; Storms, Steven; Trujillo, Tanner; Ulibarri, Mike; Vaniman, David; Whitaker, Robert; Witt, James; Maurice, Sylvestre; Bouye, Marc; Cousin, Agnes; Cros, Alain; D'Uston, Claude; Forni, Olivier; Gasnault, Olivier; Kouach, Driss; Lasue, Jeremie; Pares, Laurent; Poitrasson, Franck; Striebig, Nicolas; Thocaven, Jean-Jacques; Saccoccio, Muriel; Perez, Rene; Bell, James F. III; Hays, Charles; Blaney, Diana; DeFlores, Lauren; Elliott, Tom; Kan, Ed; Limonadi, Daniel; Lindensmith, Chris; Miller, Ed; Reiter, Joseph W.; Roberts, Tom; Simmonds, John J.; Warner, Noah; Blank, Jennifer; Bridges, Nathan; Cais, Phillippe; Clark, Benton; Cremers, David; Dyar, M. Darby; Fabre, Cecile; Herkenhoff, Ken; Kirkland, Laurel; Landis, David; Langevin, Yves; Lanza, Nina; Newsom, Horton; Ollila, Ann; LaRocca, Frank; Ott, Melanie; Mangold, Nicolas; Manhes, Gerard; Mauchien, Patrick; Blank, Jennifer; McKay, Christopher; Mooney, Joe; Provost, Cheryl; Morris, Richard V.; Sautter, Violaine; Sautter, Violaine; Waterbury, Rob; Wong-Swanson, Belinda; Barraclough, Bruce; Bender, Steve; Vaniman, David

    2012-01-01

    The ChemCam instrument suite on the Mars Science Laboratory (MSL) rover Curiosity provides remote compositional information using the first laser-induced breakdown spectrometer (LIBS) on a planetary mission, and provides sample texture and morphology data using a remote micro-imager (RMI). Overall, ChemCam supports MSL with five capabilities: remote classification of rock and soil characteristics; quantitative elemental compositions including light elements like hydrogen and some elements to which LIBS is uniquely sensitive (e.g., Li, Be, Rb, Sr, Ba); remote removal of surface dust and depth profiling through surface coatings; context imaging; and passive spectroscopy over the 240-905 nm range. ChemCam is built in two sections: The mast unit, consisting of a laser, telescope, RMI, and associated electronics, resides on the rover's mast, and is described in a companion paper. ChemCam's body unit, which is mounted in the body of the rover, comprises an optical de-multiplexer, three spectrometers, detectors, their coolers, and associated electronics and data handling logic. Additional instrument components include a 6 m optical fiber which transfers the LIBS light from the telescope to the body unit, and a set of onboard calibration targets. ChemCam was integrated and tested at Los Alamos National Laboratory where it also underwent LIBS calibration with 69 geological standards prior to integration with the rover. Post-integration testing used coordinated mast and instrument commands, including LIBS line scans on rock targets during system-level thermal-vacuum tests. In this paper we describe the body unit, optical fiber, and calibration targets, and the assembly, testing, and verification of the instrument prior to launch. (authors)

  1. Macro-Micro Interlocked Simulator

    International Nuclear Information System (INIS)

    Sato, Tetsuya

    2005-01-01

    Simulation Science is now standing on a turning point. After the appearance of the Earth Simulator, HEC is struggling with several severe difficulties due to the physical limit of LSI technologies and the so-called latency problem. In this paper I would like to propose one clever way to overcome these difficulties from the simulation algorithm viewpoint. Nature and artificial products are usually organized with several nearly autonomously working internal systems (organizations, or layers). The Earth Simulator has gifted us with a really useful scientific tool that can deal with the entire evolution of one internal system with a sufficient soundness. In order to make a leap jump of Simulation Science, therefore, it is desired to design an innovative simulator that enables us to deal with simultaneously and as consistently as possible a real system that evolves cooperatively with several internal autonomous systems. Three years experience of the Earth Simulator Project has stimulated to come up with one innovative simulation algorithm to get rid of the technological barrier standing in front of us, which I would like to call 'Macro-Micro Interlocked Algorithm', or 'Macro-Micro Multiplying Algorithm', and present a couple of such examples to validate the proposed algorithm. The first example is an aurora-arc formation as a result of the mutual interaction between the macroscopic magnetosphere-ionosphere system and the microscopic field-aligned electron and ion system. The second example is the local heavy rain fall resulting from the interaction between the global climate evolution and the microscopic raindrop growth process. Based on this innovative feasible algorithm, I came up with a Macro-Micro Multiplying Simulator

  2. Effect of Home Bleaching on the Translucency of CAD/CAM Systems.

    Science.gov (United States)

    Karci, Muhammet; Demir, Necla

    2017-11-10

    To evaluate the effect of a home bleaching agent (Opalescence PF) on the translucency of CAD/CAM ceramic systems. The 28 sintered ceramic specimens (IPS Empress CAD and IPS e.max CAD; 15 mm long, 10 mm wide, 1 mm thick) were divided into two subgroups as control and bleaching groups (n = 7). Carbamide peroxide (CP), 16%, home bleaching agent was applied onto the surface of each specimen for 6 hours per day for 7 days. A spectrophotometer (VITA Easyshade Advance) was used to measure the CIE L * a * b * coordinates and the reflectance value (Y) of the specimens on white and black backgrounds. The translucency parameter (TP), contrast ratio (CR), and opalescence parameter (OP) of the specimens were calculated. The data were statistically analyzed using Kolmogorov-Smirnov, one-way ANOVA, Tukey's test, and Pearson's correlation. Statistically significant differences in the TP values after 16% CP bleaching treatment were observed (p ˂ 0.05); however, no significant differences were found in the OP and CR values after the surface treatment (p ˃ 0.05). According to our study, patients who have all-ceramic restorations in their mouths should be careful when using home bleaching agents, because whitening agents can affect the translucency of all-ceramic restorations such as e.max CAD and Empress CAD. © 2017 by the American College of Prosthodontists.

  3. Evaluation of internal fit of interim crown fabricated with CAD/CAM milling and 3D printing system.

    Science.gov (United States)

    Lee, Wan-Sun; Lee, Du-Hyeong; Lee, Kyu-Bok

    2017-08-01

    This study is to evaluate the internal fit of the crown manufactured by CAD/CAM milling method and 3D printing method. The master model was fabricated with stainless steel by using CNC machine and the work model was created from the vinyl-polysiloxane impression. After scanning the working model, the design software is used to design the crown. The saved STL file is used on the CAD/CAM milling method and two types of 3D printing method to produce 10 interim crowns per group. Internal discrepancy measurement uses the silicon replica method and the measured data are analyzed with One-way ANOVA to verify the statistic significance. The discrepancy means (standard deviation) of the 3 groups are 171.6 (97.4) µm for the crown manufactured by the milling system and 149.1 (65.9) and 91.1 (36.4) µm, respectively, for the crowns manufactured with the two types of 3D printing system. There was a statistically significant difference and the 3D printing system group showed more outstanding value than the milling system group. The marginal and internal fit of the interim restoration has more outstanding 3D printing method than the CAD/CAM milling method. Therefore, the 3D printing method is considered as applicable for not only the interim restoration production, but also in the dental prosthesis production with a higher level of completion.

  4. The OmegaCAM 16K x 16K CCD detector system for the ESO VLT Survey Telescope (VST)

    NARCIS (Netherlands)

    Iwert, Olaf; Baade, D.; Balestra, A.; Baruffolo, A.; Bortolussi, A.; Christen, F.; Cumani, C.; Deiries, S.; Downing, M.; Geimer, C.; Hess, G.; Hess, J.; Kuijken, K.; Lizon, J.; Muschielok, B.; Nicklas, H.; Reiss, R.; Reyes, J.; Silber, A.; Thillerup, J.; Valentijn, E.; Dorn, David A.; Holland, Andrew D.

    A 16K x 16K, 1 degree x 1 degree field, detector system was developed by ESO for the OmegaCAM instrument for use on the purpose built ESO VLT Survey Telescope (VST). The focal plane consists of an 8 x 4 mosaic of 2K x 4K 15um pixel e2v CCDs and four 2K x 4K CCDs on the periphery for the

  5. 49 CFR 236.751 - Interlocking, manual.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Interlocking, manual. 236.751 Section 236.751 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Interlocking, manual. An arrangement of signals and signal appliances operated from an interlocking machine and...

  6. The National Shipbuilding Research Program. 1997 Ship Production Symposium. Implementation of Integrated CAD/CAM Systems in Small and Medium Sized Shipyards: A Case Study

    National Research Council Canada - National Science Library

    Mercier, Larry; Byington, Tracy; Senkwic, Walt; Barry, Christopher

    1997-01-01

    .... Implementing CAD/CAM is primarily a management, rather than technical, challenge. Performance-Based Management Techniques were used to develop the new system as an integrated whole, controlled and documented under ISO 9001...

  7. CAMS achievements in 1995

    International Nuclear Information System (INIS)

    Berg, Oe.; Fantoni, P.; Iguchi, Y.; Meyer, G.; Soerensen, A.; Dyck, C. van.

    1996-01-01

    CAMS (Computerized Accident Management Support) is a system being developed as a joint research activity at the Halden Reactor Project with additional financing from the Swedish Nuclear Inspectorate (SKI) and the Nordic NKS/RAK-2 project. Three types of users are envisaged: the staff in the control room, the staff in the technical support centre and the staff at a national emergency centre. It is still an experimental system. The Swedish Nuclear Inspectorate kindly accepted to test CAMS at a safety exercise on the 4th of May, 1995. CAMS is designed assuming automatic data transfer from the plant. Missing the data link, a simulator running in the next room was updated now and then with data received by phone. As seen from CAMS, it did not matter if the data came from a fake plant or from a real plant, except that the data were delayed. Overall, it seemed that CAMS can be a very important tool for a national authority. A data link from the plant would increase its usefulness. Several comments on design features were collected and will be used to improve the system. The model needs more inputs to control the main parameters, and a larger repertoire of fault conditions should be put into the model. In the second half of 1995 the work on CAMS has concentrated upon designing new modules for signal validation, tracking simulation and state identification. This will provide better capabilities for on-line monitoring and assessment of the plant state. Further, it has been proposed to introduce Probabilistic Safety Assessment (PSA) to assist in risk monitoring. A first prototype has been made on a personal computer showing the main features of such a PSA module. (au)

  8. Development of an Eccentric CAM Based Active Pre-Alignment System for the CLIC Main Beam Quadrupole Magnet

    CERN Document Server

    Lackner, F; Collette, C; Mainaud Durand, H; Hauviller, C; Kemppinen, J; Leuxe, R

    2010-01-01

    CLIC (Compact Linear Collider) is a study for a future electron-positron collider that would allow physicists to explore a new energy region beyond the capabilities of today's particle accelerators. The demanding transverse and vertical beam sizes and emittance specifications are resulting in stringent alignment and a nanometre stability requirement. In the current feasibility study, the main beam quadrupole magnets have to be actively pre-aligned with a precision of 1 µm in 5 degrees of freedom (d.o.f.) before being mechanically stabilized to the nm scale above 1 Hz. This contribution describes the approach of performing this active pre-alignment based on an eccentric cam system. In order to limit the amplification of the vibration sources at resonant frequencies a sufficiently high Eigenfrequency is required. Therefore the contact region between cam and support was optimized for adequate stiffness based on the Hertzian theory. Furthermore, practical tests performed on a single degree of freedom mock-up wil...

  9. Flexural resistance of Cerec CAD/CAM system ceramic blocks. Part 2: Outsourcing materials.

    Science.gov (United States)

    Sedda, Maurizio; Vichi, Alessandro; Del Siena, Francesco; Louca, Chris; Ferrari, Marco

    2014-02-01

    To test different Cerec CAD/CAM system ceramic blocks, comparing mean flexural strength (sigma), Weibull modulus (m), and Weibull characteristic strength (sigma0) in an ISO standardized set-up. Following the recent ISO Standard (ISO 6872:2008), 11 types of ceramic blocks were tested: IPS e.max CAD MO, IPS e.max CAD LT and IPS e.max CAD HT (lithium disilicate glass-ceramic); In-Ceram SPINELL, In-Ceram Alumina and In-Ceram Zirconia (glass-infiltrated materials); inCoris AL and In-Ceram AL (densely sintered alumina); In-Ceram YZ, IPS e.max Zir-CAD and inCoris ZI (densely sintered zirconia). Specimens were cut out from ceramic blocks, finished, crystallized/infiltrated/sintered, polished, and tested in a three-point bending test apparatus. Flexural strength, Weibull characteristic strength, and Weibull modulus were obtained. A statistically significant difference was found (P ceramic (sigma = 272.6 +/- 376.8 MPa, m = 6.2 +/- 11.3, sigma0 = 294.0 +/- 394.1 MPa) and densely sintered alumina (sigma = 441.8 +/- 541.6 MPa, m = 11.9 +/- 19.0, sigma0 = 454.2 +/- 565.2 MPa). No statistically significant difference was found (P = 0.254) in glass infiltrated materials (sigma = 376.9 +/- 405.5 MPa, m = 7.5 +/- 11.5, sigma0 = 393.7 +/- 427.0 MPa). No statistically significant difference was found (P = 0.160) in densely sintered zirconia (sigma = 1,060.8 +/- 1,227.8 MPa, m = 5.8 +/- 7.4, sigma0 = 1,002.4 +/- 1,171.0 MPa). Not all the materials tested fulfilled the requirements for the clinical indications recommended by the manufacturer.

  10. FishCam - A semi-automatic video-based monitoring system of fish migration

    Science.gov (United States)

    Kratzert, Frederik; Mader, Helmut

    2016-04-01

    One of the main objectives of the Water Framework Directive is to preserve and restore the continuum of river networks. Regarding vertebrate migration, fish passes are widely used measure to overcome anthropogenic constructions. Functionality of this measure needs to be verified by monitoring. In this study we propose a newly developed monitoring system, named FishCam, to observe fish migration especially in fish passes without contact and without imposing stress on fish. To avoid time and cost consuming field work for fish pass monitoring, this project aims to develop a semi-automatic monitoring system that enables a continuous observation of fish migration. The system consists of a detection tunnel and a high resolution camera, which is mainly based on the technology of security cameras. If changes in the image, e.g. by migrating fish or drifting particles, are detected by a motion sensor, the camera system starts recording and continues until no further motion is detectable. An ongoing key challenge in this project is the development of robust software, which counts, measures and classifies the passing fish. To achieve this goal, many different computer vision tasks and classification steps have to be combined. Moving objects have to be detected and separated from the static part of the image, objects have to be tracked throughout the entire video and fish have to be separated from non-fish objects (e.g. foliage and woody debris, shadows and light reflections). Subsequently, the length of all detected fish needs to be determined and fish should be classified into species. The object classification in fish and non-fish objects is realized through ensembles of state-of-the-art classifiers on a single image per object. The choice of the best image for classification is implemented through a newly developed "fish benchmark" value. This value compares the actual shape of the object with a schematic model of side-specific fish. To enable an automatization of the

  11. The bacterial interlocked process ONtology (BiPON): a systemic multi-scale unified representation of biological processes in prokaryotes.

    Science.gov (United States)

    Henry, Vincent J; Goelzer, Anne; Ferré, Arnaud; Fischer, Stephan; Dinh, Marc; Loux, Valentin; Froidevaux, Christine; Fromion, Vincent

    2017-11-23

    High-throughput technologies produce huge amounts of heterogeneous biological data at all cellular levels. Structuring these data together with biological knowledge is a critical issue in biology and requires integrative tools and methods such as bio-ontologies to extract and share valuable information. In parallel, the development of recent whole-cell models using a systemic cell description opened alternatives for data integration. Integrating a systemic cell description within a bio-ontology would help to progress in whole-cell data integration and modeling synergistically. We present BiPON, an ontology integrating a multi-scale systemic representation of bacterial cellular processes. BiPON consists in of two sub-ontologies, bioBiPON and modelBiPON. bioBiPON organizes the systemic description of biological information while modelBiPON describes the mathematical models (including parameters) associated with biological processes. bioBiPON and modelBiPON are related using bridge rules on classes during automatic reasoning. Biological processes are thus automatically related to mathematical models. 37% of BiPON classes stem from different well-established bio-ontologies, while the others have been manually defined and curated. Currently, BiPON integrates the main processes involved in bacterial gene expression processes. BiPON is a proof of concept of the way to combine formally systems biology and bio-ontology. The knowledge formalization is highly flexible and generic. Most of the known cellular processes, new participants or new mathematical models could be inserted in BiPON. Altogether, BiPON opens up promising perspectives for knowledge integration and sharing and can be used by biologists, systems and computational biologists, and the emerging community of whole-cell modeling.

  12. Anatomy of an energy-coupling mechanism--the interlocking catalytic cycles of the ATP sulfurylase-GTPase system.

    Science.gov (United States)

    Sun, Meihao; Leyh, Thomas S

    2005-10-25

    ATP sulfurylase, from Escherichia coli K-12, conformationally couples the rates and chemical potentials of the two reactions that it catalyzes, GTP hydrolysis and activated sulfate synthesis. The enzyme is rare among such coupling systems in that it links the potentials of small-molecule chemistries to one another, rather than to vectorial motion. The pre-steady-state stages of the catalytic cycle of ATP sulfurylase were studied using tools capable of distinguishing between enzyme-bound and solution-phase product for each of the four products of the enzyme. The study reveals that the two chemistries are linked at multiple points in the reaction coordinate. Linking begins with an isomerization prior to chemistry that initiates an ordered cleavage of the beta,gamma and alpha,beta bonds of GTP and ATP, respectively; the rates of these three sequential events increase successively, causing them to appear simultaneous. Linking is again seen in the late stages of the catalytic cycle: product release is ordered with P(i) departing prior to either GDP or PP(i). Release rate constants are determined for each product and used to construct a quantitative model of the mechanism that accurately predicts the behavior of this complex system.

  13. SPLPKG WFCMPR WFAPPX, Wilson-Fowler Spline Generator for Computer Aided Design And Manufacturing (CAD/CAM) Systems

    International Nuclear Information System (INIS)

    Fletcher, S.K.

    2002-01-01

    1 - Description of program or function: The three programs SPLPKG, WFCMPR, and WFAPPX provide the capability for interactively generating, comparing and approximating Wilson-Fowler Splines. The Wilson-Fowler spline is widely used in Computer Aided Design and Manufacturing (CAD/CAM) systems. It is favored for many applications because it produces a smooth, low curvature fit to planar data points. Program SPLPKG generates a Wilson-Fowler spline passing through given nodes (with given end conditions) and also generates a piecewise linear approximation to that spline within a user-defined tolerance. The program may be used to generate a 'desired' spline against which to compare other Splines generated by CAD/CAM systems. It may also be used to generate an acceptable approximation to a desired spline in the event that an acceptable spline cannot be generated by the receiving CAD/CAM system. SPLPKG writes an IGES file of points evaluated on the spline and/or a file containing the spline description. Program WFCMPR computes the maximum difference between two Wilson-Fowler Splines and may be used to verify the spline recomputed by a receiving system. It compares two Wilson-Fowler Splines with common nodes and reports the maximum distance between curves (measured perpendicular to segments) and the maximum difference of their tangents (or normals), both computed along the entire length of the Splines. Program WFAPPX computes the maximum difference between a Wilson- Fowler spline and a piecewise linear curve. It may be used to accept or reject a proposed approximation to a desired Wilson-Fowler spline, even if the origin of the approximation is unknown. The maximum deviation between these two curves, and the parameter value on the spline where it occurs are reported. 2 - Restrictions on the complexity of the problem - Maxima of: 1600 evaluation points (SPLPKG), 1000 evaluation points (WFAPPX), 1000 linear curve breakpoints (WFAPPX), 100 spline Nodes

  14. Interlocking directorships in Polish joint stock companies:

    OpenAIRE

    Pawlak, Marek

    2008-01-01

    Studies concerning interlocking directorships have been carried out among Polish joint stock corporations. The main source of data have been the announcements that are to be published by corporations regularly in a journal called Business and Court Gazette (BCG). Interlocking directorships constitute a network among corporations the use of which enables co-ordinated management of the whole group. The phenomenon of interlocking directorships in Polish joint stock companies can be compared to t...

  15. The VICKSI monitor interlock system

    International Nuclear Information System (INIS)

    Borchardt, D.; Kluppak, B.

    1983-01-01

    Dose rate equivalents are monitored separately for all working areas and evaluated by a central unit. The accelerator is shut off automatically if the maximum permissible concentrations given in the Radiation Protection Ordinance are exceeded and if persons are endangered. However, the experimenter may, on his own responsibility, define certain areas as 'vacated' (no staff members inside). Operation can then proceed as desired. Entry of persons into these areas is checked by the central computer. (orig./HP) [de

  16. The theory of constraints applied in a manufacture CAD-CAM system in the industry Metalworking-plastic

    Directory of Open Access Journals (Sweden)

    Luis Juiña

    2017-06-01

    Full Text Available In the following project, the theory of constraints was applied in order to implement a manufacture CAD-CAM system into the metal mechanic industry processes of polymers injection and blown of polymers. The research showed that the manufacture of the mold with the engraving took 223,17 hours. In the workflow for the manufacture of the mold, a restriction was found in the outsource service of CNC. It took 120 hours of the whole process and represent the 51,47 % the total time of tooling manufacturing. There is also a constraint found in the design time. It was 60 hours that corresponds to 26,88 % of the overall time. In order to reduce the time, a modern system of design in 3D and CAM was established to improve the model process of design and manufacture. A simulation by computational resource was applied to the plastic. The design was changed from 2D to 3D. The implementation was focused in the design. A software was installed to improve the speed of modeling methods with reliable information. In the manufacture of molds, a new CNC machine was acquired with three simultaneous axes to eliminate the outsource service. By acquiring the design system, the working time was diminished in 79% and regarding to the CNC process, the working time was improved in 88%.

  17. SpectraCam®: A new polarized hyperspectral imaging system for repeatable and reproducible in vivo skin quantification of melanin, total hemoglobin, and oxygen saturation.

    Science.gov (United States)

    Nkengne, A; Robic, J; Seroul, P; Gueheunneux, S; Jomier, M; Vie, K

    2018-02-01

    An accurate way to determine skin pigmentation is to acquire the spectral reflectance of a skin sample and to quantify chromophores by reverse calculation from physical models of light propagation. Therefore, we tested a new hyperspectral imaging device and software suite, the SpectraCam ® system, and evaluated its accuracy to quantify skin chromophores. Validation of the SpectraCam ® system was performed by, firstly, comparing the known and the acquired reflectance spectra of color phantoms. Repeatability and reproducibility were then evaluated by two operators who performed acquisitions at different time points and compared the acquired reflectance spectra. The specificity of the system was tested by quantitative analysis of single chromophore variation models: lentigo and pressure relief. Finally, we tested the ability of the SpectraCam ® system to detect variations in chromophore in the eye region due to the daily application of a new anti-dark circle cosmetic product. The SpectraCam ® system faithfully acquires the reflectance spectra of color phantoms (r 2 >0.90). The skin reflectance spectra acquired by different operators at different times are highly repeatable (r 2 >0.94) and reproducible (r 2 >0.99). The SpectraCam ® system can also produce qualitative maps that reveal local variations in skin chromophore or underlying structures such as blood vessels. The system is precise enough to detect melanin variation in lentigo or total hemoglobin and oxygen saturation variations upon pressure relief. It is also sensitive enough to detect a decrease in melanin in the eye region due to the application of an anti-dark circle cosmetic product. The SpectraCam ® system proves to be rapid and produces high-resolution data encompassing a large field of view. It is a robust hyperspectral imaging system that quantifies melanin, total hemoglobin, and oxygen saturation and is well adapted to cosmetic research. © 2017 John Wiley & Sons A/S. Published by John Wiley

  18. Software Development for Auto-Generation of Interlocking Knowledge base using Artificial Intelligence Approach

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Yun Seok [Nanseoul University (Korea); Kim, JOng Sun [Kwangwoon University (Korea)

    1999-06-01

    This paper proposes IIKBAG (Intelligent Interlocking Knowledge Base Generator) which can build automatically the interlocking knowledge base utilized as the real-time interlocking strategy of the electronic interlocking system in order to enhance it's reliability and expansion. The IIKBAG consists of the inference engine and the knowledge base. The former has an auto-learning function which searches all the train routes for the given station model based on heuristic search technique while dynamically searching the model, and then generates automatically the interlocking patterns obtained from the interlocking relations of signal facilities on the routes. The latter is designed as the structure which the real-time expert system embedded on IS (Interlocking System) can use directly in order to enhances the reliability and accuracy. The IIKBAG is implemented in C computer language for the purpose of the build and interface of the station structure database. And, a typical station model is simulated to prove the validity of the proposed IIKBAG. (author). 13 refs., 5 figs., 2 tabs.

  19. Cam Mover Alignment System positioning with the Wire Positioning with the Wire Position Sensor Feedback for CLIC

    CERN Document Server

    AUTHOR|(CDS)2077936; Mainaud Durand, Helene; Kostka, Z.S.

    2016-01-01

    Compact Linear Collider (CLIC) is a study of an electron-positron collider with nominal energy of 3 TeV and luminosity of 2 ∙ 1034 cm-2s-1. The luminosity goal leads to stringent alignment requirements for single quadrupole magnets. Vertical and lateral offset deviations with regards to a given orbit reference in both ends of a quadrupole shall be below 1 μm and quadrupole roll deviation shall be below 100 μrad. Translation in the direction of particle beam is not controlled but mechanically locked. A parallel kinematic platform based on cam movers was chosen as system for detailed studies. Earlier studies have shown that cam movers can reach the CLIC requirements through an iterative process. The paper presents new modular off-the-shelf control electronics and software including three optional positioning algorithms based on iterations as well as a more advanced algorithm which can reach target position in one movement. The advanced algorithm reads wire position sensors (WPS), calculates quadrupole orien...

  20. Validation of CLIC Re-Adjustment System Based on Eccentric Cam Movers One Degree of Freedom Mock-Up

    CERN Document Server

    Kemppinen, J; Lackner, F

    2011-01-01

    Compact Linear Collider (CLIC) is a 48 km long linear accelerator currently studied at CERN. It is a high luminosity electron-positron collider with an energy range of 0.5-3 TeV. CLIC is based on a two-beam technology in which a high current drive beam transfers RF power to the main beam accelerating structures. The main beam is steered with quadrupole magnets. To reach CLIC target luminosity, the main beam quadrupoles have to be actively pre-aligned within 17 µm in 5 degrees of freedom and actively stabilised at 1 nm in vertical above 1 Hz. To reach the pre-alignment requirement as well as the rigidity required by nano-stabilisation, a system based on eccentric cam movers is proposed for the re-adjustment of the main beam quadrupoles. Validation of the technique to the stringent CLIC requirements was started with tests in one degree of freedom on an eccentric cam mover. This paper describes the dedicated mock-up as well as the tests and measurements carried out with it. Finally, the test results are present...

  1. All Hazards Risk Assessment Transition Project: Report on Capability Assessment Management System (CAMS) Automation

    Science.gov (United States)

    2014-04-01

    Defence, 2014 © Sa Majesté la Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale, 2014 1 Abstract / Résumé...décrite en plus amples détails avec l’analyse des options. Des fonctions qui améliorent l’utilité du logiciel CAMS y sont décrites. Il s’agit...du Programme canadien pour la sûreté et la sécurité (PCSS) (CSSP-2012-TI-1108), le Centre des sciences pour la sécurité (CSS) de Recherche et

  2. Incorporation of safety interlocks in commercial robotics for handling of nuclear materials

    International Nuclear Information System (INIS)

    Moore, F.W.

    1986-01-01

    The adaptation of commercial robotic systems to applications in the manufacturing of nuclear fuel has required the addition of safety interlocks as to the handling and accountability of nuclear materials. Also, additional safety interlocks are required when the robots are operated in containment enclosures that are environmentally sealed. Interlocks have been incorporated in a commercial robot which was modified and with additional interlocks into the existing robotic control system. The robotic system has been installed in the containment enclosure as part of the pellet storage subsystem in the Secure Automated Fabrication facility currently being built by Westinghouse Hanford Company for the US Department of Energy. The system has been installed in the Fuel Cycle Plant and is scheduled for initial operational testing in 1986

  3. Designing a combined casting mold for manufacture of a gasoline centrifugal pump body using CAD/CAM-systems

    Science.gov (United States)

    Galin, N. E.; Ogol, I. I.; Chervach, Yu B.; Dammer, V. Kh; Ru, Jia Hong

    2017-02-01

    The present paper examines designing of a combined casting mold for manufacture of a gasoline centrifugal pump body. The paper offers technological solutions for obtaining high quality castings at the testing stage of the finished mold. The paper is intended for practical use and prepared by order of JSC ‘Tomsk Electrical Engineering Plant’ using software and equipment of the department ‘Technologies of Computer-Aided Machinery Manufacturing’ of the Tomsk Polytechnic University (TPU) under the economic contract within state import substitution program. In preparing the paper, CAD/CAM-systems KOMPAS-3D and PowerMILL were used. In 2015, the designed casting mold was introduced into the production process at JSC ‘Tomsk Electrical Engineering Plant’.

  4. National synchrotron light source medical personnel protection interlock

    International Nuclear Information System (INIS)

    Buda, S.; Gmur, N.F.; Larson, R.; Thomlinson, W.

    1998-01-01

    This report is founded on reports written in April 1987 by Robert Hettel for angiography operations at the Stanford Synchrotron Research Laboratory (SSRL) and a subsequent report covering angiography operations at the National Synchrotron Light Source (NSLS); BNL Informal Report 47681, June 1992. The latter report has now been rewritten in order to accurately reflect the design and installation of a new medical safety system at the NSLS X17B2 beamline Synchrotron Medical Research Facility (SMERF). Known originally as the Angiography Personnel Protection Interlock (APPI), this system has been modified to incorporate other medical imaging research programs on the same beamline and thus the name has been changed to the more generic Medical Personnel Protection Interlock (MPPI). This report will deal almost exclusively with the human imaging (angiography, bronchography, mammography) aspects of the safety system, but will briefly explain the modular aspects of the system allowing other medical experiments to be incorporated

  5. NATIONAL SYNCHROTRON LIGHT SOURCE MEDICAL PERSONNEL PROTECTION INTERLOCK

    Energy Technology Data Exchange (ETDEWEB)

    BUDA,S.; GMUR,N.F.; LARSON,R.; THOMLINSON,W.

    1998-11-03

    This report is founded on reports written in April 1987 by Robert Hettel for angiography operations at the Stanford Synchrotron Research Laboratory (SSRL) and a subsequent report covering angiography operations at the National Synchrotron Light Source (NSLS); BNL Informal Report 47681, June 1992. The latter report has now been rewritten in order to accurately reflect the design and installation of a new medical safety system at the NSLS X17B2 beamline Synchrotron Medical Research Facility (SMERF). Known originally as the Angiography Personnel Protection Interlock (APPI), this system has been modified to incorporate other medical imaging research programs on the same beamline and thus the name has been changed to the more generic Medical Personnel Protection Interlock (MPPI). This report will deal almost exclusively with the human imaging (angiography, bronchography, mammography) aspects of the safety system, but will briefly explain the modular aspects of the system allowing other medical experiments to be incorporated.

  6. Hyper Suprime-Cam: System design and verification of image quality

    Science.gov (United States)

    Miyazaki, Satoshi; Komiyama, Yutaka; Kawanomoto, Satoshi; Doi, Yoshiyuki; Furusawa, Hisanori; Hamana, Takashi; Hayashi, Yusuke; Ikeda, Hiroyuki; Kamata, Yukiko; Karoji, Hiroshi; Koike, Michitaro; Kurakami, Tomio; Miyama, Shoken; Morokuma, Tomoki; Nakata, Fumiaki; Namikawa, Kazuhito; Nakaya, Hidehiko; Nariai, Kyoji; Obuchi, Yoshiyuki; Oishi, Yukie; Okada, Norio; Okura, Yuki; Tait, Philip; Takata, Tadafumi; Tanaka, Yoko; Tanaka, Masayuki; Terai, Tsuyoshi; Tomono, Daigo; Uraguchi, Fumihiro; Usuda, Tomonori; Utsumi, Yousuke; Yamada, Yoshihiko; Yamanoi, Hitomi; Aihara, Hiroaki; Fujimori, Hiroki; Mineo, Sogo; Miyatake, Hironao; Oguri, Masamune; Uchida, Tomohisa; Tanaka, Manobu M.; Yasuda, Naoki; Takada, Masahiro; Murayama, Hitoshi; Nishizawa, Atsushi J.; Sugiyama, Naoshi; Chiba, Masashi; Futamase, Toshifumi; Wang, Shiang-Yu; Chen, Hsin-Yo; Ho, Paul T. P.; Liaw, Eric J. Y.; Chiu, Chi-Fang; Ho, Cheng-Lin; Lai, Tsang-Chih; Lee, Yao-Cheng; Jeng, Dun-Zen; Iwamura, Satoru; Armstrong, Robert; Bickerton, Steve; Bosch, James; Gunn, James E.; Lupton, Robert H.; Loomis, Craig; Price, Paul; Smith, Steward; Strauss, Michael A.; Turner, Edwin L.; Suzuki, Hisanori; Miyazaki, Yasuhito; Muramatsu, Masaharu; Yamamoto, Koei; Endo, Makoto; Ezaki, Yutaka; Ito, Noboru; Kawaguchi, Noboru; Sofuku, Satoshi; Taniike, Tomoaki; Akutsu, Kotaro; Dojo, Naoto; Kasumi, Kazuyuki; Matsuda, Toru; Imoto, Kohei; Miwa, Yoshinori; Suzuki, Masayuki; Takeshi, Kunio; Yokota, Hideo

    2018-01-01

    The Hyper Suprime-Cam (HSC) is an 870 megapixel prime focus optical imaging camera for the 8.2 m Subaru telescope. The wide-field corrector delivers sharp images of 0{^''.}2 (FWHM) in the HSC-i band over the entire 1.5° diameter field of view. The collimation of the camera with respect to the optical axis of the primary mirror is done with hexapod actuators, the mechanical accuracy of which is a few microns. Analysis of the remaining wavefront error in off-focus stellar images reveals that the collimation of the optical components meets design specifications. While there is a flexure of mechanical components, it also is within the design specification. As a result, the camera achieves its seeing-limited imaging on Maunakea during most of the time; the median seeing over several years of observing is 0.67" (FWHM) in the i band. The sensors use p-channel, fully depleted CCDs of 200 μm thickness (2048 × 4176 15 μm square pixels) and we employ 116 of them to pave the 50 cm diameter focal plane. The minimum interval between exposures is 34 s, including the time to read out arrays, to transfer data to the control computer, and to save them to the hard drive. HSC on Subaru uniquely features a combination of a large aperture, a wide field of view, sharp images and a high sensitivity especially at longer wavelengths, which makes the HSC one of the most powerful observing facilities in the world.

  7. Synthesis of interlocked molecules by olefin metathesis

    Science.gov (United States)

    Clark, Paul Gregory

    polyammonium scaffold. Diolefin polyether fragments were coordinated and "clipped" around the ammonium sites within the polymer backbone using ring-closing olefin metathesis, giving the molecular "charm bracelet". Confirmation of the interlocked nature of the product was achieved via 1H NMR spectroscopy and two-dimensional diffusion ordered NMR spectroscopy. A simple strategy for a one-pot, multi-component synthesis of polyrotaxanes using acyclic diene metathesis polymerization was developed. The polyrotaxanes were characterized by traditional 1H NMR spectroscopy as well as size exclusion chromatography, and the interlocked topology was confirmed using two-dimension diffusion-ordered NMR spectroscopy. The dynamic, self-correcting nature of the ADMET polymerization was also explored through the equilibration of a capped polyammonium polymer in the presence of dibenzo-24-crown-8 ether and olefin metathesis catalysts. The efficiency and ease with which these mechanically interlocked macromolecules can be assembled should facilitate rapid modulation to achieve versatile polyrotaxane architectures. Flexible, switchable [c2]daisy-chain dimers (DCDs) were synthesized, where the macromer ammonium binding site was adjacent to the crown-type recognition structure and separated from the cap by an alkyl chain. A DCD of this topology is expected to have an extended structure in the bound conformation (when the ammonium was coordinated to the crown). Several different macromer candidates were designed to allow access to DCDs with flexible alkyl chains between the ammonium binding site and the cap, and a number of synthetic routes were explored in an effort to access these challenging materials. While the first generation DCD structure proved to be unstable due to a labile ester linkage, work is continuing toward the development of several cap structures in an effort to replace the ester linkage with an ether linkage, which, in the second generation model systems, has proven much more stable

  8. Fluorometric Sniff-Cam (Gas-Imaging System) Utilizing Alcohol Dehydrogenase for Imaging Concentration Distribution of Acetaldehyde in Breath and Transdermal Vapor after Drinking.

    Science.gov (United States)

    Iitani, Kenta; Sato, Toshiyuki; Naisierding, Munire; Hayakawa, Yuuki; Toma, Koji; Arakawa, Takahiro; Mitsubayashi, Kohji

    2018-02-20

    Understanding concentration distributions, release sites, and release dynamics of volatile organic compounds (VOCs) from the human is expected to lead to methods for noninvasive disease screening and assessment of metabolisms. In this study, we developed a visualization system (sniff-cam) that enabled one to identify a spatiotemporal change of gaseous acetaldehyde (AcH) in real-time. AcH sniff-cam was composed of a camera, a UV-LED array sheet, and an alcohol dehydrogenase (ADH)-immobilized mesh. A reverse reaction of ADH was employed for detection of gaseous AcH where a relationship between fluorescence intensity from nicotinamide adenine dinucleotide and the concentration of AcH was inversely proportional; thus, the concentration distribution of AcH was measured by detecting the fluorescence decrease. Moreover, the image differentiation method that calculated a fluorescence change rate was employed to visualize a real-time change in the concentration distribution of AcH. The dynamic range of the sniff-cam was 0.1-10 ppm which encompassed breath AcH concentrations after drinking. Finally, the sniff-cam achieved the visualization of the concentration distribution of AcH in breath and skin gas. A clear difference of breath AcH concentration was observed between aldehyde dehydrogenase type 2 active and inactive subjects, which was attributed to metabolic capacities of AcH. AcH in skin gas showed a similar time course of AcH concentration to the breath and a variety of release concentration distribution. Using different NADH-dependent dehydrogenases in the sniff-cam could lead to a versatile method for noninvasive disease screening by acquiring spatiotemporal information on various VOCs in breath or skin gas.

  9. RF generator interlock by plasma grid bias current - An alternate to Hα interlock

    Science.gov (United States)

    Bandyopadhyay, M.; Gahlaut, A.; Yadav, R. K.; Pandya, K.; Tyagi, H.; Vupugalla, M.; Bhuyan, M.; Bhagora, J.; Chakraborty, A.

    2017-08-01

    ROBIN is inductively coupled plasma (ICP) based negative hydrogen ion source, operated with a 100kW, 1MHz Tetrode based RF generator (RFG). Inductive plasma ignition by the RFG in ROBIN is associated with electron seeding by a hot filament and a gas puff. RFG is triggered by the control system to deliver power just at the peak pressure of the gas puff. Once plasma is ignited due to proper impedance matching, a bright light, dominated by Hα (˜656nm wavelength) radiation is available inside RF driver which is used as a feedback signal to the RFG to continue its operation. If impedance matching is not correct, plasma is not produced due to lack of power coupling and bright light is not available. During such condition, reflected RF power may damage the RFG. Therefore, to protect the RFG, it needs to be switched off automatically within 200ms by the control system in such cases. This plasma light based RFG interlock is adopted from BATMAN ion source. However, in case of vacuum immersed RF ion source in reactor grade NBI system, such plasma light based interlock may not be feasible due to lack of adequate optical fiber interfaces. In reactor grade NBI system, neutron and gamma radiations have impact on materials which may lead to frequent maintenance and machine down time. The present demonstration of RFG interlock by Bias Current (BC) in ROBIN testbed gives an alternate option in this regard. In ROBIN, a bias plate (BP) is placed in the plasma chamber near the plasma grid (PG). BP is electrically connected to the plasma chamber wall of the ion source and PG is isolated from the wall. A high current ˜85 A direct current (DC) power supply of voltage in the range of 0 - 33V is connected between the PG and the BP in such a way that PG can be biased positively with respect to the BP or plasma chamber. This arrangement is actually made to absorb electrons and correspondingly reduce co-extracted electron current during beam extraction. However, in case of normal plasma

  10. Marginal fit of all-ceramic crowns fabricated using two extraoral CAD/CAM systems in comparison with the conventional technique

    Directory of Open Access Journals (Sweden)

    Alqahtani F

    2017-03-01

    Full Text Available Fawaz Alqahtani1,2 1Department of Prosthodontics, 2Higher Education and Scientific Research, School of Dentistry, Prince Sattam Bin Abdul-Aziz University, Al-kharj, Saudi Arabia Objective: The purpose of this study was to determine the effect of two extraoral computer-aided design (CAD and computer-aided manufacturing (CAM systems, in comparison with conventional techniques, on the marginal fit of monolithic CAD/CAM lithium disilicate ceramic crowns. Study design: This is an in vitro interventional study. Place and duration of study: The study was carried out at the Department of Prosthodontics, School of Dentistry, Prince Sattam Bin Abdul-Aziz University, Saudi Arabia, from December 2015 to April 2016. Methodology: A marginal gap of 60 lithium disilicate crowns was evaluated by scanning electron microscopy. In total, 20 pressable lithium disilicate (IPS e.max Press [Ivoclar ­Vivadent] ceramic crowns were fabricated using the conventional lost-wax technique as a control group. The experimental all-ceramic crowns were produced based on a scan stone model and milled using two extraoral CAD/CAM systems: the Cerec group was fabricated using the Cerec CAD/CAM system, and the Trios group was fabricated using Trios CAD and milled using Wieland Zenotec CAM. One-way analysis of variance (ANOVA and the Scheffe post hoc test were used for statistical comparison of the groups (α=0.05. Results: The mean (±standard deviation of the marginal gap of each group was as follows: the Control group was 91.15 (±15.35 µm, the Cerec group was 111.07 (±6.33 µm, and the Trios group was 60.17 (±11.09 µm. One-way ANOVA and the Scheffe post hoc test showed a statistically significant difference in the marginal gap between all groups. Conclusion: It can be concluded from the current study that all-ceramic crowns, fabricated using the CAD/CAM system, show a marginal accuracy that is acceptable in clinical environments. The Trios CAD group displayed the smallest

  11. A comparison of outcomes according to different diagnostic systems for delirium (DSM-5, DSM-IV, CAM, and DRS-R98).

    Science.gov (United States)

    Adamis, Dimitrios; Meagher, David; Rooney, Siobhan; Mulligan, Owen; McCarthy, Geraldine

    2017-09-14

    Studies indicate that DSM-5 criteria for delirium are relatively restrictive, and identify different cases of delirium compared with previous systems. We evaluate four outcomes of delirium (mortality, length of hospital stay, institutionalization, and cognitive improvement) in relation to delirium defined by different DSM classification systems. Prospective, longitudinal study of patients aged 70+ admitted to medical wards of a general hospital. Participants were assessed up to a maximum of four times during two weeks, using DSM-5 and DSM-IV criteria, DRS-R98 and CAM scales as proxies for DSM III-R and DSM III. Of the 200 assessed patients (mean age 81.1, SD = 6.5; and 50% female) during hospitalization, delirium was identified in 41 (20.5%) using DSM-5, 45 (22.5%) according to DSM-IV, 46 (23%) with CAM positive, and 37 (18.5%) with DRS-R98 severity score >15. Mortality was significantly associated with delirium according to any classification system, but those identified with DSM-5 were at greater risk. Length of stay was significantly longer for those with DSM-IV delirium. Discharge to a care home was associated only with DRS-R98 defined delirium. Cognitive improvement was only associated with CAM and DSM-IV. Different classification systems for delirium identify populations with different outcomes.

  12. Design of test JIG for centralized interlock and protection module of ITER-India Gyrotron Test Facility

    International Nuclear Information System (INIS)

    Rathod, Vipal; Rao, S.L.; Edappala, Praveenlal; Rajpal, Rachana

    2017-01-01

    Fast Interlock and protection system plays very crucial role in ensuring the safe and reliable operation of high power RF sources such as a Gyrotron system. Critical Protection Interlocks are generally implemented using hardwired components and are required to have a response time as fast as < 10 μs. In this context, an Industrial grade prototype Centralized Interlock and Protection Module (CIM) based on ITER-India design has been developed successfully with the help of local industry. This paper presents the complete requirements, approach, detailed design concept and current status of Test JIG in detail

  13. Eye irritation potential: usefulness of the HET-CAM under the Globally Harmonized System of classification and labeling of chemicals (GHS).

    Science.gov (United States)

    Scheel, Julia; Kleber, Marcus; Kreutz, Jürgen; Lehringer, Elke; Mehling, Annette; Reisinger, Kerstin; Steiling, Winfried

    2011-04-01

    Extensive research has been conducted over the past decades to develop alternatives to the rabbit eye irritation test (Draize test) used in a regulatory context to assess eye irritation potentials. Although no single in vitro test has emerged as being completely acceptable for full replacement, various tests are considered to be suitable and are regularly used to assess certain aspects. Amongst these, the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) has gained regulatory acceptance in various countries to classify severe eye irritants. In this retrospective study, historical eye irritation data (in vivo and in vitro) from 137 samples (approx. 75% non-irritants; 25% (severe) irritants) tested both in the HET-CAM and Draize eye test was compared with regard to the predicted eye irritation classes under the GHS and the traditional EU classification system (DSD).The overall concordance was in the range of 80-90%. A high specificity (96-98%, depending on the classification system and the chosen discrimination) but rather low sensitivity (48-65%) was observed. The study indicates that HET-CAM results are useful as part of weight-of-evidence assessments or in tiered approaches to assess eye irritation potentials rather than as stand-alone classification method. Copyright © 2011 Elsevier Inc. All rights reserved.

  14. Response of the East Asian climate system to water and heat changes of global frozen soil using NCAR CAM model

    Science.gov (United States)

    Xin, Y.

    2017-12-01

    Under the condition of land-atmosphere heat and water conservation, a set of sensitive numerical experiments are set up to investigate the response of the East Asian climate system to global frozen soil change. This is done by introducing the supercooled soil water process into the Community Land Model (CLM3.0), which has been coupled to the National Center of Atmospheric Research Community Atmosphere Model (CAM3.1). Results show that: 1) The ratio between soil ice and soil water in CLM3.0 is clearly changed by the supercooled soil water process. Ground surface temperature and soil temperature are also affected. 2) The Eurasian (including East Asian) climate system is sensitive to changes of heat and water in frozen soil regions. In January, the Aleutian low sea level pressure circulation is strengthened, Ural blocking high at 500 hPa weakened, and East Asian trough weakened. In July, sea level pressure over the Aleutian Islands region is significantly reduced; there are negative anomalies of 500 hPa geopotential height over the East Asian mainland, and positive anomalies over the East Asian ocean. 3) In January, the southerly component of the 850 hPa wind field over East Asia increases, indicating a weakened winter monsoon. In July, cyclonic anomalies appear on the East Asian mainland while there are anticyclonic anomalies over the ocean, reflective of a strengthened east coast summer monsoon. 4) Summer rainfall in East Asia changed significantly, including substantial precipitation increase on the southern Qinghai-Tibet Plateau, central Yangtze River Basin, and northeast China. Summer rainfall significantly decreased in south China and Hainan Island, but slightly decreased in central and north China. Further analysis showed considerable upper air motion along 30°N latitude, with substantial descent of air at its north and south sides. Warm and humid air from the Northeast Pacific converged with cold air from northern land areas, representing the main cause of

  15. 21 CFR 876.4590 - Interlocking urethral sound.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Interlocking urethral sound. 876.4590 Section 876...) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Surgical Devices § 876.4590 Interlocking urethral sound. (a) Identification. An interlocking urethral sound is a device that consists of two metal sounds...

  16. Incorporation of safety interlocks in commercial robotics for handling of nuclear materials

    International Nuclear Information System (INIS)

    Moore, F.W.

    1986-01-01

    Current robotic systems have been developed primarily for the automotive and electronic industry. The adaptation of these commercial robotic systems to applications in the manufacturing of nuclear fuel requires the addition of safety interlocks as to the handling and accountability of nuclear materials. Also, additional safety interlocks are required when the robots are operated in containment enclosures that are environmentally sealed. Interlocks have been incorporated into a commercial robot. The robotic system has been installed in the containment enclosure as part of the pellet storage subsystem into the Secure Automated Fabrication (SAF) facility currently being built by Westinghouse Hanford Company (WHC) for the US Department of Energy (DOE). The system has been installed in the Fuel Cycle Plant and is scheduled for initial operational testing in 1986

  17. Evaluation of marginal and internal adaptations of posterior all-ceramic crowns fabricated with chair-side CAD/CAM system: an in vitro study

    Directory of Open Access Journals (Sweden)

    Merve Bankoğlu Güngör

    2018-01-01

    Full Text Available Objective: Advances in chair-side Computer-Aided Design / Computer-Aided Manufacturing (CAD/CAM technology and materials science currently enable the fabrication of highly esthetic restorations for the anterior and posterior teeth. However, there is a lack of evidence regarding the marginal and internal adaptations of new CAD/CAM materials. The objective of this study was to evaluate the marginal and internal adaptations of posterior all-ceramic restorations fabricated from contemporary restorative materials with chair-side CAD/CAM system. Materials and Method: An artificial mandibular left first molar tooth was prepared according to standard tooth preparation procedures, and standard models of the prepared teeth were obtained. All-ceramic restorations (n=10 were fabricated from seven different CAD/CAM blocks (IPS e.max CAD, Lava Ultimate, Incoris TZI, Incoris ZI, Vita Suprinity, Vita Enamic, and GC Cerasmart. The marginal and internal adaptations were measured with silicone replicas, which were sectioned with a thin lancet. The discrepancy between the die and the inner surface of the restoration was examined at 50× magnification by using a light microscope with digital camera. Four reference points were examined at each buccal-lingual section and eight reference points were examined at each mesial-distal section. The results were evaluated by two-way analysis of variance (ANOVA followed by Tukey HSD test (α=0.05. Results: The values obtained from marginal-internal areas were generally greater than those in the marginal areas. Significant differences were found between the materials. The statistical analysis revealed that there was an interaction between the material type and the location of the reference points (p<0.05; the lowest values were observed in axial areas, and the highest values were observed in occlusal areas. Conclusion: All materials showed low marginal and internal discrepancies which were considered clinically acceptable.

  18. Final report on a cold climate permeable interlocking concrete pavement test facility at the University of New Hampshire Stormwater Center.

    Science.gov (United States)

    2013-05-01

    University of New Hampshire Stormwater Center (UNHSC) completed a two year field verification study of a permeable interlocking concrete pavement (PICP) stormwater management system. The purpose of this study was to evaluate the cold climate function...

  19. Effectiveness and complications of SIGN intramedullary interlocking ...

    African Journals Online (AJOL)

    Background: Interlocking intramedullary nailing is the current state-of-the-art management of the shaft fractures of long bones. Objective: To assess the functional outcome of SIGN nailing of femoral and tibial fractures at Moi Teaching and Referral Hospital. Design: Retrospective analytical, study over a three year period ...

  20. A Visual Servoing-Based Method for ProCam Systems Calibration

    Directory of Open Access Journals (Sweden)

    Jeremie Mosnier

    2013-10-01

    Full Text Available Projector-camera systems are currently used in a wide field of applications, such as 3D reconstruction and augmented reality, and can provide accurate measurements, depending on the configuration and calibration. Frequently, the calibration task is divided into two steps: camera calibration followed by projector calibration. The latter still poses certain problems that are not easy to solve, such as the difficulty in obtaining a set of 2D–3D points to compute the projection matrix between the projector and the world. Existing methods are either not sufficiently accurate or not flexible. We propose an easy and automatic method to calibrate such systems that consists in projecting a calibration pattern and superimposing it automatically on a known printed pattern. The projected pattern is provided by a virtual camera observing a virtual pattern in an OpenGL model. The projector displays what the virtual camera visualizes. Thus, the projected pattern can be controlled and superimposed on the printed one with the aid of visual servoing. Our experimental results compare favorably with those of other methods considering both usability and accuracy.

  1. National Synchrotron Light Source angiography personnel protection interlock

    International Nuclear Information System (INIS)

    Gmuer, N.; Larson, R.; Thomlinson, W.

    1992-06-01

    This document has been written to describe the safety system operation at the NSLS X17B2 beamline Synchrotron Medical Research Facility (SMERF). The angiography exposure process involves scanning a patient up and down through dual fixed-position x-ray beams; exposure is controlled by opening and closing a fast-acting Safety Shutter mechanism at precise times in relation to the up and down motion of the scan chair. The fast-acting Safety Shutter mechanism is the primary radiation-stopping element protecting the patient while the chair is at rest and while it is reversing directions during the scan. Its fail-safe and fast operation is essential for the safety of the patient. Operation of X17B2 as a human subject angiography station necessitates the implementation of a personnel protection interlock system that, in conjunction with the Safety Shutters: permits safe access to the patient exposure area while the synchrotron radiation beam is illuminating the upstream dual energy monochromator; allows a patient to be imaged by the monochromatized beam under the supervision of a Responsible Physician, with scan chair motion and precision shutter actuation regulated by an angiography control computer, while providing a suitable number of safeguards against accidental radiation exposure; has different modes of operation to accommodate equipment set-up, test, and calibration; and patient exposure; and ensures the quick extinction of the beam if a potentially unsafe condition is detected. The interlock system which performs these safety functions is called the Angiography Personnel Protection Interlock (APPI). The APPI Document is organized such that the level of detail changes from a general overview to detailed engineering drawings of the hardware system

  2. National Synchrotron Light Source angiography personnel protection interlock

    Energy Technology Data Exchange (ETDEWEB)

    Gmuer, N.; Larson, R.; Thomlinson, W.

    1992-06-01

    This document has been written to describe the safety system operation at the NSLS X17B2 beamline Synchrotron Medical Research Facility (SMERF). The angiography exposure process involves scanning a patient up and down through dual fixed-position x-ray beams; exposure is controlled by opening and closing a fast-acting Safety Shutter mechanism at precise times in relation to the up and down motion of the scan chair. The fast-acting Safety Shutter mechanism is the primary radiation-stopping element protecting the patient while the chair is at rest and while it is reversing directions during the scan. Its fail-safe and fast operation is essential for the safety of the patient. Operation of X17B2 as a human subject angiography station necessitates the implementation of a personnel protection interlock system that, in conjunction with the Safety Shutters: permits safe access to the patient exposure area while the synchrotron radiation beam is illuminating the upstream dual energy monochromator; allows a patient to be imaged by the monochromatized beam under the supervision of a Responsible Physician, with scan chair motion and precision shutter actuation regulated by an angiography control computer, while providing a suitable number of safeguards against accidental radiation exposure; has different modes of operation to accommodate equipment set-up, test, and calibration; and patient exposure; and ensures the quick extinction of the beam if a potentially unsafe condition is detected. The interlock system which performs these safety functions is called the Angiography Personnel Protection Interlock (APPI). The APPI Document is organized such that the level of detail changes from a general overview to detailed engineering drawings of the hardware system.

  3. Any Monotone Function Is Realized by Interlocked Polygons

    Directory of Open Access Journals (Sweden)

    Erik D. Demaine

    2012-03-01

    Full Text Available Suppose there is a collection of n simple polygons in the plane, none of which overlap each other. The polygons are interlocked if no subset can be separated arbitrarily far from the rest. It is natural to ask the characterization of the subsets that makes the set of interlocked polygons free (not interlocked. This abstracts the essence of a kind of sliding block puzzle. We show that any monotone Boolean function ƒ on n variables can be described by m = O(n interlocked polygons. We also show that the decision problem that asks if given polygons are interlocked is PSPACE-complete.

  4. Elaboration of the configuration and programming of the interlocks system of the TRIGA Mark III reactor; Elaboracion de la configuracion y programacion del sistema de interbloqueos del reactor Triga Mark III

    Energy Technology Data Exchange (ETDEWEB)

    Mejia C, M. A.

    2016-07-01

    The modernization of the TRIGA Mark III reactor interlock system requires a system that provides high reliability, flexibility and ease of operation during reactor operation. With this modernization of the system, is intended to prevent, control and mitigate the causes of probable accidents reported in the reactor accident analysis. On the other hand, is foreseen the ease reactor operation in a simple, safe and efficient way. The programmable logic controller can be programmed by programming instructions using simple language and easy to develop, these can be modified from a computer using the programming software. In addition, another of the advantages offered by the controller is that can be modified from a touch screen (human-machine interface) that allows adjustment, without the need to use programming software and diagnostic functions during the process. As a result of the present work, a situation of improvement in the reactor operation was generated, facilitating the handling of the bridge and increasing the efficiency of the system in the execution of the operating conditions of the installations external to the reactor. A modern, more reliable and much less expensive system was achieved than the previous one, avoiding that the maintenance to the system generates high expenses. With respect to the development of the application programming, a control was implemented that allows to select a zone of the five that have inside the pool to carry out the displacement of automatic way and later to be located in that zone, having in this way a greater efficiency and ease in bridge control. (Author)

  5. Camønoen

    DEFF Research Database (Denmark)

    Gyimóthy, Szilvia; Widtfeld Meged, Jane

    2016-01-01

    is augmented by a digital platform on which hikers may directly connect with local citizens and book experiences ranging from private dinners to bird-watching and berry-picking. The platform Camønoen.org is hosted by the regional museum, which neither charges for intermediation, nor is responsible for vetting...... and citizens alike? The recently opened pilgrim trail, Camønoen represents an adapted collaborative business model and as such an appropriate case to study new coastal value creation processes. Camønoen is a 175 km long newly designed walking trail across the islands of Møn, Nyord and Bogø. The trail...

  6. CAM and stack air sampler design guide

    International Nuclear Information System (INIS)

    Phillips, T.D.

    1994-01-01

    About 128 air samplers and CAMs presently in service to detect and document potential radioactive release from 'H' and 'F' area tank farm ventilation stacks are scheduled for replacement and/or upgrade by Projects S-5764, S-2081, S-3603, and S-4516. The seven CAMs scheduled to be upgraded by Project S-4516 during 1995 are expected to provide valuable experience for the three remaining projects. The attached document provides design guidance for the standardized High Level Waste air sampling system

  7. CAMS: OLAPing Multidimensional Data Streams Efficiently

    Science.gov (United States)

    Cuzzocrea, Alfredo

    In the context of data stream research, taming the multidimensionality of real-life data streams in order to efficiently support OLAP analysis/mining tasks is a critical challenge. Inspired by this fundamental motivation, in this paper we introduce CAMS (C ube-based A cquisition model for M ultidimensional S treams), a model for efficiently OLAPing multidimensional data streams. CAMS combines a set of data stream processing methodologies, namely (i) the OLAP dimension flattening process, which allows us to obtain dimensionality reduction of multidimensional data streams, and (ii) the OLAP stream aggregation scheme, which aggregates data stream readings according to an OLAP-hierarchy-based membership approach. We complete our analytical contribution by means of experimental assessment and analysis of both the efficiency and the scalability of OLAPing capabilities of CAMS on synthetic multidimensional data streams. Both analytical and experimental results clearly connote CAMS as an enabling component for next-generation Data Stream Management Systems.

  8. The "Kluge-Lüttge Kammer": a preliminary evaluation of an enclosed, Crassulacean acid metabolism (CAM) Mesocosm that allows separation of synchronized and desynchronized contributions of plants to whole system gas exchange.

    Science.gov (United States)

    Rascher, U; Bobich, E G; Osmond, C B

    2006-01-01

    Crassulacean acid metabolism (CAM) is recognized as a photosynthetic adaptation of plants to arid habitats. This paper presents a proof-of-concept evaluation of partitioning net CO2 exchanges for soil and plants in an arid, exclusively CAM mesocosm, with soil depth and succulent plant biomass approximating that of natural Sonoran Desert ecosystems. We present the first evidence that an enclosed CAM-dominated soil and plant community exposed to a substantial day/night temperature difference (30/20 degrees C), exhibits a diel gas exchange pattern consisting of four consecutive phases with a distinct nocturnal CO2 uptake. These phases were modulated by plant assimilation and soil respiration processes. Day-time stomatal closure of the CAM cycle during phase III was used to eliminate aboveground photosynthetic assimilation and respiration and thereby to estimate belowground plant plus soil respiration. Rapid changes in temperature appeared to synchronize single plant gas exchange but individual plant gas exchange patterns were desynchronized at constant day/night temperatures (25 degrees C), masking the distinct mesocosm pattern. Overall, the mean carbon budget of this CAM model Sonoran Desert system was negative, releasing an average of 22.5 mmol CO2 m-2 d-1. The capacity for nocturnal CO2 assimilation in this exclusively CAM mesocosm was inadequate to recycle CO2 released by plant and soil respiration.

  9. Test plan for FY-91 alpha CAM evaluation

    International Nuclear Information System (INIS)

    Winberg, M.R.

    1991-03-01

    This report describes the test plan for evaluating the Merlin Gerin, Inc., Edgar alpha continuous air monitor (CAM) and associated analysis system to be conducted by Idaho National Engineering Laboratory (INEL) for the Department of Energy. INEL has evaluated other commercial alpha CAM systems to detect transuranic contaminants during waste handling and retrieval operations. This test plan outlines experimental methods, sampling methods, sampling and analysis techniques, and equipment needed and safety and quality requirements to test the commercial CAM. 8 refs., 3 figs

  10. INTERFIRM COOPERATION AND INFORMATION SHARING THROUGH INTERLOCKING DIRECTORATES

    Directory of Open Access Journals (Sweden)

    Mohammed Belal UDDIN

    2012-01-01

    Full Text Available When firms engage in cooperative efforts, interfirm relations get particular interest to be studied. A direct interlock occurs when an executive or director of one firm sits on the board of another firm, and an indirect interlock occurs when two firms have directors or executives who sit on the board of a third firm. The three commonly used theoretical models such as social network theory, learning theory, and theory of strategic choice are more relevant for the formation and management of interlocking directorates. Uncertainty, resource scarcity, mutual trust, dependency, etc. influence the formation of interlocking directorates. Consequently, interlocking directorates allow sharing of information and overall cooperation between partners through learning, collaboration, networking, and effective relationship, etc. Proper management of interlocking directorates requires communication and collaboration among partners that enhance exchange of knowledge and cooperation.

  11. Development of Interlocking Masonry Bricks and its’ Structural Behaviour: A Review Paper

    Science.gov (United States)

    Al-Fakih, Amin; Mohammed, Bashar S.; Nuruddin, Fadhil; Nikbakht, Ehsan

    2018-04-01

    Conventional bricks are the most elementary building materials for houses construction. However, the rapid growth in today’s construction industry has obliged the civil engineers in searching for a new building technique that may result in even greater economy, more efficient and durable as an alternative for the conventional brick. Moreover, the high demands for having a speedy and less labour and cost building systems is one of the factor that cause the changes of the masonry conventional systems. These changes have led to improved constructability, performance, and cost as well. Several interlocking bricks has been developed and implemented in building constructions and a number of researches had studied the manufacturing of interlocking brick and its structural behaviour as load bearing and non-load bearing element. This technical paper aims to review the development of interlocking brick and its structural behaviour. In conclusion, the concept of interlocking system has been widely used as a replacement of the conventional system where it has been utilized either as load bearing or non-load bearing masonry system.

  12. Wear at the Implant-Abutment Interface of Zirconia Abutments Manufactured by Three CAD/CAM Systems.

    Science.gov (United States)

    Pinheiro Tannure, Ana Luiza; Cunha, Alfredo Gonçalves; Borges Junior, Luiz Antônio; da Silva Concílio, Laís Regiane; Claro Neves, Ana Christina

    To evaluate the changes in the external-hexagon surface of the titanium (Ti) implant before and after mechanical cycling, when coupled with zirconia (Zr) abutments (A) manufactured by three computer-aided design/computer-aided manufacturing (CAD/CAM) systems (Neodent Digital, Zirkonzahn, and AmannGirrbach) and the ZrTi abutment manufactured by Neodent. Four groups were formed (n = 6): titanium implant with Zr AmannGirrbach abutment (AZrAG), with Zr Zirkonzahn abutment (AZrZ), with Zr Neodent abutment (AZrN), and with Zr abutment with infrastructure in Ti Neodent (AZrTiN). Standardized abutments were made from three identical abutments milled in wax. Images of the surface of each side of the hexagons of the implant were obtained by scanning electron microscopy, before and after mechanical cycling, to evaluate the parameters: (1) scratches in the hexagon face; (2) hexagon superior shoulder kneading; (3) hexagon shoulder wear; (4) alterations on the hexagon base; and (5) scratches on the hexagon top. The abutments were coupled with the implants, and Cr-Co crowns were cemented. The implant/abutment/crown assemblies were submitted to mechanical cycling (400 N, 8.0 Hz) for 1 million cycles. The observed changes were classified as follows: absence (0), mild (1), moderate (2), and severe (3). The results were analyzed using the Mann-Whitney, Kruskal-Wallis, and Dunn tests (P < .05). For parameter 1, a significant difference (P = .008) was observed between AZrZ and AZrAG, with more scratches in AZrZ; and between AZrN and AZrTiN (P = .006), with more scratches in AZrN. For parameter 2, a significant difference (P < .05) was observed between AZrZ and AZrAG and between AZrZ and AZrN, with greater kneading in AZrZ; among AZrN and AZrTiN, there was no significant difference (P = .103). For parameter 3, a significant difference (P < .05) was observed between AZrZ and the other groups of Zr, with more wear in AZrZ; between AZrN and AZrTiN, there was no significant difference (P

  13. 46 CFR 111.70-7 - Remote control, interlock, and indicator circuits.

    Science.gov (United States)

    2010-10-01

    ... ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Motor Circuits, Controllers, and Protection § 111.70-7..., interlock, or indicator circuit of a motor controller must be protected against overcurrent unless: (1) The... hazard. Note: For overcurrent protection of steering gear control and indicator circuits, see Subpart 111...

  14. PreCam

    Energy Technology Data Exchange (ETDEWEB)

    Allam, Sahar S. [Fermilab; Tucker, Douglas L. [Fermilab

    2015-01-01

    The Dark Energy Survey (DES) will be taking the next step in probing the properties of Dark Energy and in understanding the physics of cosmic acceleration. A step towards the photometric calibration of DES is to have a quick, bright survey in the DES footprint (PreCam), using a pre-production set of the Dark Energy Camera (DECam) CCDs and a set of 100 mm×100 mm DES filters. The objective of the PreCam Survey is to create a network of calibrated DES grizY standard stars that will be used for DES nightly calibrations and to improve the DES global relative calibrations. Here, we describe the first year of PreCam observation, results, and photometric calibrations.

  15. Ex vivo torsional properties of a 2.5 mm veterinary interlocking nail system in canine femurs. Comparison with a 2.4 mm limited contact bone plate.

    Science.gov (United States)

    Macedo, Aline S; Moens, Noel M M; Runciman, John; Gibson, Tom W G; Minto, Bruno W

    2017-03-20

    To evaluate the torsional properties of the Targon ® Vet Nail System (TVS) in small canine femurs and to compare these properties to those of the 2.4 mm LC-DCP ® plates. Thirty-six cadaveric femurs were allocated to three groups (n = 12). In all bones, points just distal to the lesser trochanter and just proximal to the fabellae were marked and a midshaft transverse osteotomy was performed. Group 1: bones were fixed with the 2.5 mm TVS with the bolts applied at the pre-identified marks. Group 2: A TVS system with 25% shorter inter-bolt distance was used. Group 3: A 7-hole 2.4 mm LC-DCP ® plates were applied. All constructs were tested non-destructively for 10 cycles, followed by an acute torsion to failure. Torque at yield was 0.806 ± 0.183 and 0.805 ± 0.093 Nm for groups 1 and 2 and 1.737 ± 0.461 Nm for group 3. Stiffness was 0.05 ± 0.01, 0.05 ± 0.007, and 0.14 ± 0.015 Nm/° for groups 1 to 3 respectively. Maximal angular displacement under cyclic loading was 16.6° ± 2.5°, 15.6° ± 2.1°, and 7.8° ± 1.06° respectively. There was no significant difference for any of the parameters between groups 1 and 2. Both torque at yield and stiffness were significantly greater between group 3 and groups 1 and 2. The TVS had approximately half the torsional strength and approximately 1/3 of the stiffness of the 2.4 mm bone plate. Slippage of the locking mechanism was probably the cause of the early failure. The system should be considered as a low-strength and low-stiffness system when compared to bone plates.

  16. A DUAL NETWORK MODEL OF INTERLOCKING DIRECTORATES

    Directory of Open Access Journals (Sweden)

    Humphry Hung

    2003-01-01

    Full Text Available The article proposes an integrative framework for the study of interlocking directorates by using an approach that encompasses the concepts of multiple networks and resource endowment. This serves to integrate the traditional views of interorganizational linkages and intra-class cohesion. Through appropriate strategic analysis of relevant resource endowment of internal environment and external networks of organizations and corporate elites, this article argues that the selection of directors, if used effectively, can be adopted as a strategic device to enhance the corporation's overall performance.

  17. An 8-year evaluation of sintered ceramic and glass ceramic inlays processed by the Cerec CAD/CAM system

    DEFF Research Database (Denmark)

    Pallesen, U.; Dijken van, J.W.V.

    2000-01-01

    sensitivity was reported by one patient for 8 months. Of the 32 inlays evaluated during the 8 yr, 3 failed due to fracture of the material. No secondary caries was found adjacent to the inlays. No significant differences in the clinical performance were found between inlays made of the two ceramics. It can......The purpose of this study was to evaluate Cerec CAD/CAM inlays processed of two industrially made machinable ceramics during an 8-yr follow-up period. Each of 16 patients received two similar ceramic inlays. Half the number of the inlays were made of a feldspathic (Vita Mark II) and the other...... of a glass ceramic (Dicor MGC) block. The inlays were luted with a dual resin composite and evaluated clinically using modified USPHS criteria at baseline, 8 months, 2, 3, 5, 6 and 8 yr, and indirectly using models. At baseline, 84% of the inlays were estimated as optimal and 16% as acceptable. Postoperative...

  18. An 8-year evaluation of sintered ceramic and glass ceramic inlays processed by the Cerec CAD/CAM system

    DEFF Research Database (Denmark)

    Pallesen, U.; Dijken van, J.W.V.

    2000-01-01

    of a glass ceramic (Dicor MGC) block. The inlays were luted with a dual resin composite and evaluated clinically using modified USPHS criteria at baseline, 8 months, 2, 3, 5, 6 and 8 yr, and indirectly using models. At baseline, 84% of the inlays were estimated as optimal and 16% as acceptable. Postoperative......The purpose of this study was to evaluate Cerec CAD/CAM inlays processed of two industrially made machinable ceramics during an 8-yr follow-up period. Each of 16 patients received two similar ceramic inlays. Half the number of the inlays were made of a feldspathic (Vita Mark II) and the other...... sensitivity was reported by one patient for 8 months. Of the 32 inlays evaluated during the 8 yr, 3 failed due to fracture of the material. No secondary caries was found adjacent to the inlays. No significant differences in the clinical performance were found between inlays made of the two ceramics. It can...

  19. Structural damage monitoring of harbor caissons with interlocking condition

    Energy Technology Data Exchange (ETDEWEB)

    Huynh, Thanh Canh; Lee, So Young; Nauyen, Khac Duy; Kim, Jeong Tae [Pukyong National Univ., Busan (Korea, Republic of)

    2012-12-15

    The objective of this study is to monitor the health status of harbor caissons which have potential foundation damage. To obtain the objective, the following approaches are performed. Firstly, a structural damage monitoring(SDM) method is designed for interlocked multiple caisson structures. The SDM method utilizes the change in modal strain energy to monitor the foundation damage in a target caisson unit. Secondly, a finite element model of a caisson system which consists of three caisson units is established to verify the feasibility of the proposed method. In the finite element simulation, the caisson units are constrained each other by shear key connections. The health status of the caisson system against various levels of foundation damage is monitored by measuring relative modal displacements between the adjacent caissons.

  20. Structural damage monitoring of harbor caissons with interlocking condition

    International Nuclear Information System (INIS)

    Huynh, Thanh Canh; Lee, So Young; Nauyen, Khac Duy; Kim, Jeong Tae

    2012-01-01

    The objective of this study is to monitor the health status of harbor caissons which have potential foundation damage. To obtain the objective, the following approaches are performed. Firstly, a structural damage monitoring(SDM) method is designed for interlocked multiple caisson structures. The SDM method utilizes the change in modal strain energy to monitor the foundation damage in a target caisson unit. Secondly, a finite element model of a caisson system which consists of three caisson units is established to verify the feasibility of the proposed method. In the finite element simulation, the caisson units are constrained each other by shear key connections. The health status of the caisson system against various levels of foundation damage is monitored by measuring relative modal displacements between the adjacent caissons

  1. Dual Interlocked Logic for Single-Event Transient Mitigation

    Science.gov (United States)

    2017-03-01

    Dual Interlocked Logic for Single -Event Transient Mitigation Jeffrey Maharrey, Jeffrey Kauppila, Dennis Ball, Timothy Holman, Lloyd Massengill...is shown to be robust to single event transients. Keywords: SET; CVSL; DIL; single event transient; hardened logic; cascode voltage switch; dual...interlocked Introduction Single event transients (SETs) generated in combinational logic are a major, often dominant, contributor to soft errors in

  2. DATA TRANSLATION BETWEEN PADS AND CAM350

    Directory of Open Access Journals (Sweden)

    E. B. Romanova

    2015-07-01

    Full Text Available The subject matter of the paper is the process of data translation between computer-aided design system for electronic devices PADS VX and system for technological preparation of production of printed circuit boards CAM350 10. The object of this study is two-way translation of data in these systems. Experimental researches are applied as research methods based on repeated playback of forward and reverse data translation process between PADS and CAM350 systems. The aim is to examine the challenges of data exchange between systems and to find out the ways of their solution. The basis of the work is functionality analysis of PADS and CAM350 systems while data translation, which was carried out in the course of operating experience of these systems. The paper presents advantages and disadvantages of translation methods and their comparison. Errors arising in the process are analyzed. Possible reasons of errors origination are described. The main results are recommendations for data exchange between PADS and CAM350 systems. The proposed recommendations give the possibility to optimize the exchange of data between these systems. Practical significance of the work lies in the implementation of results at LLC «Abeo». Recommendations have been used in the development of dozens of different electronic devices. The use of these results made it possible to reduce the production run-up time, to increase data transmission correctness, thereby improving the quality of products and reduction of their cost.

  3. Effectiveness of CAM therapy: understanding the evidence.

    Science.gov (United States)

    Staud, Roland

    2011-02-01

    By definition, complementary and alternative medicine (CAM) attempts to diagnose and treat illnesses in unconventional ways. CAM has been classified as: (1) alternative medical systems (eg, traditional Chinese medicine [including acupuncture], naturopathic medicine, ayurvedic medicine, and homeopathy); (2) biologic-based therapies (eg, herbal, special dietary, and individual biologic treatments); (3) energy therapies (eg, Reiki, therapeutic touch, magnet therapy, Qi Gong, and intercessory prayer); (4) manipulative and body-based systems (eg, chiropractic, osteopathy, and massage); and (5) mind-body interventions (eg, meditation, biofeedback, hypnotherapy, and the relaxation response). This review focuses on how to assess the effectiveness of CAM therapies for chronic musculoskeletal pains, emphasizing the role of specific and nonspecific analgesic mechanisms, including placebo. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. An in vivo evaluation of fit of zirconium-oxide based ceramic single crowns, generated with two CAD/CAM systems, in comparison to metal ceramic single crowns.

    Science.gov (United States)

    Biscaro, Leonello; Bonfiglioli, Roberto; Soattin, Massimo; Vigolo, Paolo

    2013-01-01

    The purpose of this study was to assess in vivo the marginal fit of single crowns produced using two CAD/CAM all-ceramic systems, in comparison to more traditional metal ceramic crowns. Thirty vital, caries-free, and previously untreated teeth were chosen in five patients who needed extraction for implant placement and therefore were included in this study. In the control group (C), 10 regular metal ceramic crowns with porcelain occlusal surfaces were fabricated. In the other two groups (Z and E), CAD/CAM technology was used for the fabrication of 20 zirconium-oxide-based ceramic single crowns with two systems. All zirconia crowns were cemented with glass-ionomer cement, always following the manufacturer's instructions. The same dentist carried out all clinical phases. The teeth were extracted 1 month later. Marginal gaps along vertical planes were measured for each crown, using a total of four landmarks for each tooth by means of a microscope at a magnification of 50×. On completion of microscopic evaluation, representative specimens from each group were prepared for ESEM evaluation. Mean and standard deviations of the four landmarks (mesial, distal, buccal, palatal) at each single crown were calculated for each group. Multivariate analysis of variance (MANOVA) was performed to determine whether the four landmarks, taken into consideration together, differed between groups. Two-way ANOVA was performed to study in detail, for each landmark, how the three systems used to produce the FPDs affected the gap measurements. Differences were considered to be significant at p compared to more traditional metal ceramic crowns. © 2012 by the American College of Prosthodontists.

  5. Cam Drive Step Mechanism of a Quadruped Robot

    Directory of Open Access Journals (Sweden)

    Qun Sun

    2014-01-01

    Full Text Available Bionic quadruped robots received considerable worldwide research attention. For a quadruped robot walking with steady paces on a flat terrain, using a cam drive control mechanism instead of servomotors provides theoretical and practical benefits as it reduces the system weight, cost, and control complexities; thus it may be more cost beneficial for some recreational or household applications. This study explores the robot step mechanism including the leg and cam drive control systems based on studying the bone structure and the kinematic step sequences of dog. The design requirements for the cam drive robot legs have been raised, and the mechanical principles of the leg operating mechanism as well as the control parameters have been analyzed. A cam drive control system was constructed using three cams to control each leg. Finally, a four-leg demo robot was manufactured for experiments and it showed stable walking patterns on a flat floor.

  6. The secreted immunoglobulin domain proteins ZIG-5 and ZIG-8 cooperate with L1CAM/SAX-7 to maintain nervous system integrity.

    Directory of Open Access Journals (Sweden)

    Claire Y Bénard

    Full Text Available During nervous system development, neuronal cell bodies and their axodendritic projections are precisely positioned through transiently expressed patterning cues. We show here that two neuronally expressed, secreted immunoglobulin (Ig domain-containing proteins, ZIG-5 and ZIG-8, have no detectable role during embryonic nervous system development of the nematode Caenorhabditis elegans but are jointly required for neuronal soma and ventral cord axons to maintain their correct position throughout postembryonic life of the animal. The maintenance defects observed upon removal of zig-5 and zig-8 are similar to those observed upon complete loss of the SAX-7 protein, the C. elegans ortholog of the L1CAM family of adhesion proteins, which have been implicated in several neurological diseases. SAX-7 exists in two isoforms: a canonical, long isoform (SAX-7L and a more adhesive shorter isoform lacking the first two Ig domains (SAX-7S. Unexpectedly, the normally essential function of ZIG-5 and ZIG-8 in maintaining neuronal soma and axon position is completely suppressed by genetic removal of the long SAX-7L isoform. Overexpression of the short isoform SAX-7S also abrogates the need for ZIG-5 and ZIG-8. Conversely, overexpression of the long isoform disrupts adhesion, irrespective of the presence of the ZIG proteins. These findings suggest an unexpected interdependency of distinct Ig domain proteins, with one isoform of SAX-7, SAX-7L, inhibiting the function of the most adhesive isoform, SAX-7S, and this inhibition being relieved by ZIG-5 and ZIG-8. Apart from extending our understanding of dedicated neuronal maintenance mechanisms, these findings provide novel insights into adhesive and anti-adhesive functions of IgCAM proteins.

  7. Breath Alcohol Ignition Interlock Devices : Policy and Implementing Implications [Mobile .MP4 (480x320/29.97fps/13.9MB)

    Science.gov (United States)

    2011-01-01

    The goal of this project is to perform a systematic review of breath alcohol ignition interlock devices (BAIID or IID) to understand how other states have integrated such systems into administrative and judicial practice and to make recommendations f...

  8. Breath Alcohol Ignition Interlock Devices : Policy and Implementing Implications [SD .MP4 (640x424/29.97fps/22.6MB)

    Science.gov (United States)

    2011-01-01

    The goal of this project is to perform a systematic review of breath alcohol ignition interlock devices (BAIID or IID) to understand how other states have integrated such systems into administrative and judicial practice and to make recommendations f...

  9. Roller Cam Positioners

    Energy Technology Data Exchange (ETDEWEB)

    Bowden, Gordon B.

    2010-12-07

    Roller Cam Positioners could support the LCLS undulator sections allowing micron sized alignment adjustment of each undulator in 5 degrees of freedom. The supports are kinematic with the number of degrees of freedom matched to the number of constraints. Ton loads are supported on simple ball bearings. Motion is intrinsically bounded. Positioning mechanisms are based on pure rolling motion with sub-micron hysteresis and micron resolution. This note describes a general purpose positioning mechanism suitable for undulator support.

  10. Effect of software version and parameter settings on the marginal and internal adaptation of crowns fabricated with the CAD/CAM system.

    Science.gov (United States)

    Shim, Ji Suk; Lee, Jin Sook; Lee, Jeong Yol; Choi, Yeon Jo; Shin, Sang Wan; Ryu, Jae Jun

    2015-10-01

    This study investigated the marginal and internal adaptation of individual dental crowns fabricated using a CAD/CAM system (Sirona's BlueCam), also evaluating the effect of the software version used, and the specific parameter settings in the adaptation of crowns. Forty digital impressions of a master model previously prepared were acquired using an intraoral scanner and divided into four groups based on the software version and on the spacer settings used. The versions 3.8 and 4.2 of the software were used, and the spacer parameter was set at either 40 μm or 80 μm. The marginal and internal fit of the crowns were measured using the replica technique, which uses a low viscosity silicone material that simulates the thickness of the cement layer. The data were analyzed using a Friedman two-way analysis of variance (ANOVA) and paired t-tests with significance level set at psoftware version (psoftware showed a better fit than those designed with the version 3.8, particularly in the axial wall and in the inner margin. The spacer parameter was more accurately represented in the version 4.2 of the software than in the version 3.8. In addition, the use of the version 4.2 of the software combined with the spacer parameter set at 80 μm showed the least variation. On the other hand, the outer margin was not affected by the variables. Compared to the version 3.8 of the software, the version 4.2 can be recommended for the fabrication of well-fitting crown restorations, and for the appropriate regulation of the spacer parameter.

  11. The business prestige: A preliminary study based on interlocks within companies El prestigi empresarial: Anàlisi a través de les conselleries creuades The business prestige: A preliminary study based on interlocks within companies

    Directory of Open Access Journals (Sweden)

    David Gonzalez-Prieto

    2011-11-01

    enterprises.Objecte: En la literatura sobre xarxes de conselleries creuades, interlocked directorate o interlocks, s’ha plantejat la presència de consellers creuats com un factor influent en el prestigi d'una empresa (Mizruchi, 1996. Aquesta teoria es basa en què, pel fet de tenir diversos interlocks amb empreses importants, els stakeholders de l'empresa n’haurien de tenir una percepció de prestigi més elevada. El que es pretén amb aquest estudi preliminar és presentar un estudi exploratori i plantejar línies futures de recerca sobre aquesta qüestió.Disseny/metodologia: Per En un primer estudi preliminar, s'ha avaluat la xarxa d’interlocks que componen les empreses pertanyents al rànquing de l'Informe MERCO 2010 d'Espanya. Aquest és un rànquing de reputació corporativa de gran èxit a Espanya i en actual expansió internacional ja utilitzat en articles recents (Luna & Fernández, 2010. Per a més profunditat d'anàlisi es consideraran altres variables com cotitzar en l'índex de referència del mercat espanyol, l'IBEX 35, i la localització de la seu social.Resultats: S’obtenen relacions positives significatives entre la quantitat de conselleries comunes amb altres empreses i la percepció de prestigi que dóna l'empresa als seusstakeholders. Paral·lelament, s'obtenen relacions positives significatives entre el prestigi i el cotitzar en l'IBEX 35. Finalment, s'identifiquen banca, construcció i energia com els sectors que fan un ús més intensiu de les conselleries creuades.Limitacions: Els resultats d’aquest estudi preliminar obren el camí a futurs estudis sobre la influència entre el prestigi i els interlocks (Mizruchi, 1996. Per una validació de la teoria descrita s’hauria de replicar aquest estudi en diferents regions i, amb una mostra major observar l'efecte que tenen les conselleries creuades sobre la percepció de prestigi de l'empresa.Implicacions pràctiques/Valor afegit: Aquest és el primer estudi que mostra la exist

  12. The Use of Circular Arc Cams for the Command of a Robotic System. Part II: Application to Knife Edge Translating Follower

    Directory of Open Access Journals (Sweden)

    Stelian Alaci

    2014-12-01

    Full Text Available In the second part of paper the results from the first part are applied to the cam mechanisms with knife-edge translating follower. First, a method for characterizing the tangency points fulfilling the actual constraints of the problem is identified. Applying this criterion, a set of equidistant points is generated on the whole geometrical locus of tangency points and the characteristics of approximating circles are found. Considering all replacement solutions, the kinematical analysis for all cam mechanisms with approximate profiles is made, choosing amid them the one performing the closest kinematical behavior to the exact cam mechanism.

  13. Optimising the cam profile of an electronic unit pump for a heavy-duty diesel engine

    International Nuclear Information System (INIS)

    Qiu, Tao; Dai, Hefei; Lei, Yan; Cao, Chunlei; Li, Xuchu

    2015-01-01

    For a fuel system with a tangent cam or a constant-velocity cam, the peak injection pressure continues to rise as the injection duration increases, but overly high peak pressures induce mechanical loads and wear, limiting the maximum engine speed and injection quantity. To improve the performance of an EUP (Electronic Unit Pump) fuel system for heavy-duty diesel engines, this work proposes a new pump cam, namely the constant-pressure cam. It helps the EUP run at a higher speed and deliver larger fuel quantities while maintaining a constant peak injection pressure, which improves the power of the heavy-duty diesel engine. A model based on the EUP was built to determine the three constraints for optimising the constant-pressure cam: 1) the pump pressure should equal the nozzle pressure; 2) the cam speed should decrease with the increase in the injection duration; and 3) the cam acceleration gradient should be zero. An EUP system was tested with the tangent cam and the optimised cam under different conditions. The experimental results show that the EUP system with the optimised cam delivers more injection quantity and runs at higher engine speeds while maintaining the same peak pressure as the tangent cam. - Highlights: • We propose a constant-pressure cam to improve the power of heavy-duty diesel engine. • We deduce three constraints for the CP (constant-peak pressure) cam based on a model. • The EUP system with the new cam works well under higher engine speed. • The peak pressure of the constant-pressure cam fuel system maintains high

  14. Considering biomedical/CAM treatments

    OpenAIRE

    Cheng, JX; Widjaja, F; Choi, JE; Hendren, RL

    2013-01-01

    Complementary and alternative medicine (CAM) is widely used to treat children with psychiatric disorders. In this review, MedLine was searched for various biomedical/CAM treatments in combination with the key words "children," "adolescents," "psychiatric disorders," and "complementary alternative medicine." The biomedical/CAM treatments most thoroughly researched were omega-3 fatty acids, melatonin, and memantine. Those with the fewest published studies were N-acetylcysteine, vitamin B 12 , a...

  15. In Vitro Comparative Analysis of Fracture Resistance in Inlay Restoration Prepared with CAD-CAM and Different Systems in the Primary Teeth.

    Science.gov (United States)

    Simsek, Huseyin; Derelioglu, Sera

    2016-01-01

    Objective . The aim of this study was to compare to fracture resistance test of inlay restorations prepared using direct inlay technique (Gradia® Direct Composite) and Indirect Restoration System® (Gradia Indirect Composite) and CAD/CAD system (Vita Enamic® Block). Study Design . 48 noncarious extracted maxillary second primary molars were randomly divided into 4 groups with 12 in each group. All the teeth were prepared based on inlay class II preparations except for the control group. Other groups were restored with Gradia Direct Composite, Gradia Indirect Composite, and Vita Enamic Block, respectively. All restorations were cemented self-adhesive dual cure resin (3M Espe, RelyX™ Unicem Aplicap). A fracture test was performed using a compressive load. Results were analyzed using one-way analysis of variance and Duncan's post hoc multiple comparison tests ( α = 0.05). Results . Vita Enamic Block and Gradia Indirect Composite showed significantly higher fracture resistance than Gradia Direct Composite ( p 0.05). All restorations tested led to a significant reduction in fracture resistance ( p inlay restorations, Indirect Restoration Systems and CAD/CAM systems were applied successfully together with the self-adhesive dual cure resin cements in primary molars.

  16. Fracture Union in Closed Interlocking Nail in Humeral Shaft Fractures

    Directory of Open Access Journals (Sweden)

    Ramji Lal Sahu

    2015-01-01

    Conclusions: The results of the present study indicates that in the presence of proper indications, reamed antegrade intramedullary interlocked nailing appears to be a method of choice for internal fixation of osteoporotic and pathologic fractures.

  17. Finite element analysis to study the effects of using CAD/CAM glass-fiber post system in a severely damaged anterior tooth.

    Science.gov (United States)

    Chen, Aijie; Feng, Xiaoli; Zhang, Yanli; Liu, Ruoyu; Shao, Longquan

    2015-01-01

    To investigate the stress distribution of a severely damaged maxillary anterior tooth restored with a computer-aided design/computer-aided manufacturing (CAD/CAM) glass-fiber post system. Twelve models were fabricated with different alveolar bone levels and cervical dentin wall thicknesses and studied using a two-dimensional finite element method. A force of 100 N was applied to the lingual surface of the crown at 45 degrees, and the maximum von Mises stress was calculated. A higher stress level was observed in the dentin than in the post and crown. With the reduction of dentin thickness, the maximum von Mises stress in the dentin increased slightly to a peak at a thickness of 1.5 mm, followed by a slight decrease at a thickness of 1.0 mm. However, the relative ratio (RR) values did not show a large difference (RR > 80%). Meanwhile, a large difference in RR values was observed with a change in bone level (RR fiber post system, the maximal von Mises stress was significantly affected by the bone level, rather than by the dentin thickness. Moreover, this system may be applied to the treatment of a maxillary anterior tooth with a bone level of only 2/3.

  18. A Focus on Triazolium as a Multipurpose Molecular Station for pH-Sensitive Interlocked Crown-Ether-Based Molecular Machines.

    Science.gov (United States)

    Coutrot, Frédéric

    2015-10-01

    The control of motion of one element with respect to others in an interlocked architecture allows for different co-conformational states of a molecule. This can result in variations of physical or chemical properties. The increase of knowledge in the field of molecular interactions led to the design, the synthesis, and the study of various systems of molecular machinery in a wide range of interlocked architectures. In this field, the discovery of new molecular stations for macrocycles is an attractive way to conceive original molecular machines. In the very recent past, the triazolium moiety proved to interact with crown ethers in interlocked molecules, so that it could be used as an ideal molecular station. It also served as a molecular barrier in order to lock interlaced structures or to compartmentalize interlocked molecular machines. This review describes the recently reported examples of pH-sensitive triazolium-containing molecular machines and their peculiar features.

  19. Automatic generation and verification of railway interlocking control tables using FSM and NuSMV

    Directory of Open Access Journals (Sweden)

    Mohammad B. YAZDI

    2009-01-01

    Full Text Available Due to their important role in providing safe conditions for train movements, railway interlocking systems are considered as safety critical systems. The reliability, safety and integrity of these systems, relies on reliability and integrity of all stages in their lifecycle including the design, verification, manufacture, test, operation and maintenance.In this paper, the Automatic generation and verification of interlocking control tables, as one of the most important stages in the interlocking design process has been focused on, by the safety critical research group in the School of Railway Engineering, SRE. Three different subsystems including a graphical signalling layout planner, a Control table generator and a Control table verifier, have been introduced. Using NuSMV model checker, the control table verifier analyses the contents of control table besides the safe train movement conditions and checks for any conflicting settings in the table. This includes settings for conflicting routes, signals, points and also settings for route isolation and single and multiple overlap situations. The latest two settings, as route isolation and multiple overlap situations are from new outcomes of the work comparing to works represented on the subject recently.

  20. Artificial nanomachines based on interlocked molecules

    International Nuclear Information System (INIS)

    Credi, Alberto

    2006-01-01

    The extension of the concept of machine to the molecular level is of great interest for the growth of nanoscience and the development of nanotechnology. A molecular machine can be defined as an assembly of a discrete number of molecular components (that is, a supramolecular structure) designed to perform a function through the mechanical movements of its components, which occur under appropriate external stimulation. Hence, molecular machines contain a motor part, that is a device capable of converting energy into mechanical work. Molecular motors and machines operate via nuclear rearrangements and, like their macroscopic counterparts, are characterized by the kind of energy input supplied to make them work, the manner in which their operation can be monitored, the possibility to repeat the operation at will, i.e., establishing a cyclic process, the timescale needed to complete a cycle of operation, and the performed function. Owing to the progresses made in several branches of chemistry, and to the better understanding of the operation mechanisms of molecular machines of the biological world, it has become possible to design and construct simple prototypes of artificial molecular motors and machines. Some examples based on rotaxanes, catenanes, and related interlocked molecules will be described

  1. Optimisation Methods for Cam Mechanisms

    Directory of Open Access Journals (Sweden)

    Claudia–Mari Popa

    2010-01-01

    Full Text Available In this paper we present the criteria which represent the base of optimizing the cam mechanisms and also we perform the calculations for several types of mechanisms. We study the influence of the constructive parameters in case of the simple machines with rotation cam and follower (flat or curve of translation on the curvature radius and that of the transmission angle. As it follows, we present the optimization calculations of the cam and flat rotation follower mechanisms, as well as the calculations for optimizing the cam mechanisms by circular groove followers’ help. For an easier interpretation of the results, we have visualized the obtained cam in AutoCAD according to the script files generated by a calculation program.

  2. Effect of software version and parameter settings on the marginal and internal adaptation of crowns fabricated with the CAD/CAM system

    Directory of Open Access Journals (Sweden)

    Ji Suk SHIM

    2015-10-01

    Full Text Available Objective This study investigated the marginal and internal adaptation of individual dental crowns fabricated using a CAD/CAM system (Sirona’s BlueCam, also evaluating the effect of the software version used, and the specific parameter settings in the adaptation of crowns.Material and Methods Forty digital impressions of a master model previously prepared were acquired using an intraoral scanner and divided into four groups based on the software version and on the spacer settings used. The versions 3.8 and 4.2 of the software were used, and the spacer parameter was set at either 40 μm or 80 μm. The marginal and internal fit of the crowns were measured using the replica technique, which uses a low viscosity silicone material that simulates the thickness of the cement layer. The data were analyzed using a Friedman two-way analysis of variance (ANOVA and paired t-tests with significance level set at p<0.05.Results The two-way ANOVA analysis showed the software version (p<0.05 and the spacer parameter (p<0.05 significantly affected the crown adaptation. The crowns designed with the version 4.2 of the software showed a better fit than those designed with the version 3.8, particularly in the axial wall and in the inner margin. The spacer parameter was more accurately represented in the version 4.2 of the software than in the version 3.8. In addition, the use of the version 4.2 of the software combined with the spacer parameter set at 80 μm showed the least variation. On the other hand, the outer margin was not affected by the variables.Conclusion Compared to the version 3.8 of the software, the version 4.2 can be recommended for the fabrication of well-fitting crown restorations, and for the appropriate regulation of the spacer parameter.

  3. Alcohol ignition interlock programmes for reducing drink driving recidivism.

    Science.gov (United States)

    Willis, C; Lybrand, S; Bellamy, N

    2004-10-18

    An ignition interlock device is part of a multi-dimensional programme aimed at reducing recidivism in convicted drink drivers. To operate a vehicle equipped with an ignition interlock device, the driver must first provide a breath specimen. If the breath alcohol concentration of the specimen exceeds the predetermined level, the vehicle will not start. As a measure to reduce circumvention of the device (i.e. someone else blows into the mouthpiece), random retests are required while the vehicle is running. Other components of the drink driving programme include information seminars for the driver and downloading data from the device's data logger, which logs all test attempts and records all passes, warnings and failures. To systematically assess the effectiveness of ignition interlock programmes on recidivism rates of drink drivers, by examining rates of recidivism while the ignition interlock device was installed in the vehicle and after removal of the device. The Cochrane Controlled Trials Register was searched, in addition to relevant electronic databases and the Internet. Controlled trials in which offenders have been charged with drink driving and have either been sentenced to participate in an ignition interlock programme or the usual punishment (either licence suspension or some form of treatment programme). This study was not restricted by language or status of publication. One randomised controlled trial (RCT) and ten controlled trials were identified, and also three ongoing trials. Data regarding recidivism while the interlock is installed in the vehicle; after the interlock has been removed from the vehicle and total recidivism during the study were extracted and entered into analyses using RevMan. The RCT showed that the interlock programme was effective while the device was installed in the vehicle; relative risk 0.36 (95% confidence interval 0.21 to 0.63). Controlled trials support this conclusion, with a general trend - in both first-time and repeat

  4. Extending DIII-D Neutral Beam Modulated Operations with a Camac Based Total on Time Interlock

    International Nuclear Information System (INIS)

    Baggest, D.S.; Broesch, J.D.; Phillips, J.C.

    1999-01-01

    A new total-on-time interlock has increased the operational time limits of the Neutral Beam systems at DIII-D. The interlock, called the Neutral Beam On-Time-Limiter (NBOTL), is a custom built CAMAC module utilizing a Xilinx 9572 Complex Programmable Logic Device (CPLD) as its primary circuit. The Neutral Beam Injection Systems are the primary source of auxiliary heating for DIII-D plasma discharges and contain eight sources capable of delivering 20MW of power. The delivered power is typically limited to 3.5 s per source to protect beam-line components, while a DIII-D plasma discharge usually exceeds 5 s. Implemented as a hardware interlock within the neutral beam power supplies, the NBOTL limits the beam injection time. With a continuing emphasis on modulated beam injections, the NBOTL guards against command faults and allows the beam injection to be safely spread over a longer plasma discharge time. The NBOTL design is an example of incorporating modern circuit design techniques (CPLD) within an established format (CAMAC). The CPLD is the heart of the NBOTL and contains 90% of the circuitry, including a loadable, 1 MHz, 28 bit, BCD count down timer, buffers, and CAMAC communication circuitry. This paper discusses the circuit design and implementation. Of particular interest is the melding of flexible modern programmable logic devices with the CAMAC format

  5. Analysis of operator support method based on intelligent dynamic interlock in lead-cooled fast reactor simulator

    International Nuclear Information System (INIS)

    Xu, Peng; Wang, Jianye; Yang, Minghan; Wang, Weitian; Bai, Yunqing; Song, Yong

    2017-01-01

    Highlights: • We development an operator support method based on intelligent dynamic interlock. • We offer an integrated aid system to reduce the working strength of operators. • The method can help operators avoid dangerous, irreversible operation. • This method can be used in the fusion research reactor in the further. - Abstract: In nuclear systems, operators have to carry out corrective actions when abnormal situations occur. However, operators might make mistakes under pressure. In order to avoid serious consequences of the human errors, a new method for operators support based on intelligent dynamic interlock was proposed. The new method based on full digital instrumentation and control system, contains real-time alarm analysis process, decision support process and automatic safety interlock process. Once abnormal conditions occur, necessary safety interlock parameter based on analysis of real-time alarm and decision support process can be loaded into human-machine interfaces and controllers automatically, and avoid human errors effectively. Furthermore, the new method can make recommendations for further use and development of this technique in nuclear power plant or fusion research reactor.

  6. A State of the Art Report of CAD/CAM/CIM Systems Technologies for the U.S. Shipbuilding Industry

    Science.gov (United States)

    2002-05-01

    system, which detects the edges and coverts the data to a set of measurement features. The system located the corresponding design model, which...the RP process 52 via a VRML file format or *.STL file format. As a publishing technology, RP can be evaluated relative to other styles of

  7. Outcome of intramedullary interlocking SIGN nail in tibial diaphyseal fracture

    International Nuclear Information System (INIS)

    Khan, I.; Javed, S.; Khan, G.N.; Aziz, A.

    2013-01-01

    Objective: To determine the outcome of intramedullary interlocking surgical implant generation network (SIGN) nail in diaphyseal tibial fractures in terms of union and failure of implant (breakage of nail or interlocking screws). Study Design: Case series. Place and Duration of Study: Orthopaedics and Spinal Surgery, Ghurki Trust Teaching Hospital, Lahore Medical and Dental College, Lahore, from September 2008 to August 2009. Methodology: Fifty patients aged 14 - 60 years, of either gender were included, who had closed and Gustilo type I and II open fractures reported in 2 weeks, whose closed reduction was not possible or was unsatisfactory and fracture was located 7 cm below knee joint to 7 cm above ankle joint. Fractures previously treated with external fixator, infected fractures and unfit patients were excluded. All fractures were fixed with intramedullary interlocking SIGN nail and were followed clinically and radiographically for union and for any implant failure. Results: Forty one (88%) patients had united fracture within 6 months, 5 (10%) patients had delayed union while 4 (8%) patients had non-union. Mean duration for achieving union was 163 + 30.6 days. Interlocking screws were broken in 2 patients while no nail was broken in any patient. Conclusion: Intramedullary interlocking nailing is an effective measure in treating closed and grade I and II open tibial fractures. It provides a high rate of union less complications and early return to function. (author)

  8. Poly[n]catenanes: Synthesis of molecular interlocked chains

    Science.gov (United States)

    Wu, Qiong; Rauscher, Phillip M.; Lang, Xiaolong; Wojtecki, Rudy J.; de Pablo, Juan J.; Hore, Michael J. A.; Rowan, Stuart J.

    2017-12-01

    As the macromolecular version of mechanically interlocked molecules, mechanically interlocked polymers are promising candidates for the creation of sophisticated molecular machines and smart soft materials. Poly[n]catenanes, where the molecular chains consist solely of interlocked macrocycles, contain one of the highest concentrations of topological bonds. We report, herein, a synthetic approach toward this distinctive polymer architecture in high yield (~75%) via efficient ring closing of rationally designed metallosupramolecular polymers. Light-scattering, mass spectrometric, and nuclear magnetic resonance characterization of fractionated samples support assignment of the high-molar mass product (number-average molar mass ~21.4 kilograms per mole) to a mixture of linear poly[7-26]catenanes, branched poly[13-130]catenanes, and cyclic poly[4-7]catenanes. Increased hydrodynamic radius (in solution) and glass transition temperature (in bulk materials) were observed upon metallation with Zn2+.

  9. Quantitative analysis of digital outcrop data obtained from stereo-imagery using an emulator for the PanCam camera system for the ExoMars 2020 rover

    Science.gov (United States)

    Barnes, Robert; Gupta, Sanjeev; Gunn, Matt; Paar, Gerhard; Balme, Matt; Huber, Ben; Bauer, Arnold; Furya, Komyo; Caballo-Perucha, Maria del Pilar; Traxler, Chris; Hesina, Gerd; Ortner, Thomas; Banham, Steven; Harris, Jennifer; Muller, Jan-Peter; Tao, Yu

    2017-04-01

    A key focus of planetary rover missions is to use panoramic camera systems to image outcrops along rover traverses, in order to characterise their geology in search of ancient life. This data can be processed to create 3D point clouds of rock outcrops to be quantitatively analysed. The Mars Utah Rover Field Investigation (MURFI 2016) is a Mars Rover field analogue mission run by the UK Space Agency (UKSA) in collaboration with the Canadian Space Agency (CSA). It took place between 22nd October and 13th November 2016 and consisted of a science team based in Harwell, UK, and a field team including an instrumented Rover platform at the field site near Hanksville (Utah, USA). The Aberystwyth University PanCam Emulator 3 (AUPE3) camera system was used to collect stereo panoramas of the terrain the rover encountered during the field trials. Stereo-imagery processed in PRoViP is rendered as Ordered Point Clouds (OPCs) in PRo3D, enabling the user to zoom, rotate and translate the 3D outcrop model. Interpretations can be digitised directly onto the 3D surface, and simple measurements can be taken of the dimensions of the outcrop and sedimentary features, including grain size. Dip and strike of bedding planes, stratigraphic and sedimentological boundaries and fractures is calculated within PRo3D from mapped bedding contacts and fracture traces. Merging of rover-derived imagery with UAV and orbital datasets, to build semi-regional multi-resolution 3D models of the area of operations for immersive analysis and contextual understanding. In-simulation, AUPE3 was mounted onto the rover mast, collecting 16 stereo panoramas over 9 'sols'. 5 out-of-simulation datasets were collected in the Hanksville-Burpee Quarry. Stereo panoramas were processed using an automated pipeline and data transfer through an ftp server. PRo3D has been used for visualisation and analysis of this stereo data. Features of interest in the area could be annotated, and their distances between to the rover

  10. Engine testing of ceramic cam-roller followers

    Energy Technology Data Exchange (ETDEWEB)

    Kalish, Y. (Detroit Diesel Corp., MI (United States))

    1992-04-01

    For several years, DDC has been developing monolithic ceramic heat engine components. One of the components, developed for an application in our state-of-the-art on-highway, heavy-duty diesel engine, the Series 60, is a silicon nitride cam-roller follower. Prior to starting this program, each valve train component in the Series 60 was considered for conversion to a ceramic material. Many advantages and disadvantages (benefits and risks) were considered. From this effort, one component was selected, the cam-roller follower. Using a system design approach, a ceramic cam-roller follower offered functional improvement at a reasonable cost. The purpose of the project was to inspect and test 100 domestically produced silicon nitride cam-roller followers built to the requirements of the DDC series 60 engine.

  11. Engine testing of ceramic cam-roller followers. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kalish, Y. [Detroit Diesel Corp., MI (United States)

    1992-04-01

    For several years, DDC has been developing monolithic ceramic heat engine components. One of the components, developed for an application in our state-of-the-art on-highway, heavy-duty diesel engine, the Series 60, is a silicon nitride cam-roller follower. Prior to starting this program, each valve train component in the Series 60 was considered for conversion to a ceramic material. Many advantages and disadvantages (benefits and risks) were considered. From this effort, one component was selected, the cam-roller follower. Using a system design approach, a ceramic cam-roller follower offered functional improvement at a reasonable cost. The purpose of the project was to inspect and test 100 domestically produced silicon nitride cam-roller followers built to the requirements of the DDC series 60 engine.

  12. An integrated CAD/CAM system for CNG pressure vessel manufactured by deep drawing and ironing operation

    Energy Technology Data Exchange (ETDEWEB)

    Park, Joon Hong; Kim, Chul; Choi, Jae Chan [Pusan National Univ., Pusan (Korea, Republic of)

    2004-06-01

    The fiber reinforced composite material is widely used in the multi-industrial field because of their high specific modulus and specific strength. It has two main merits which are to cut down energy by reducing weight and to prevent explosive damage proceeding to the sudden bursting which is generated by the pressure leakage condition. Therefore, pressure vessels using this composite material can be applied in the field such as defence industry and aerospace industry. In this paper, for nonlinear finite element analysis of E-glass/epoxy filament winding of composite vessel subjected to internal pressure, the standard interpretation model is developed by using the ANSYS with AutoLISP and ANSYS APDL languages, general commercial software, which is verified as useful characteristic of the solution. Among the modules of the system, both the process planning module for carrying out the process planning of filament wound composite pressure vessel and the autofrettage process module for obtaining higher residual stress will minimize trial and error and reduce the period for developing new products. The system can serve as a valuable system for experts and as a dependable training aid for beginners.

  13. CAM and Post-Traumatic Stress Disorder

    Directory of Open Access Journals (Sweden)

    Alex Hankey

    2007-01-01

    Full Text Available In the form of the Transcendental Meditation program CAM offers a method of eliminating deep-rooted stress, the efficacy of which has been demonstrated in several related studies. Any discussion of CAM and post-traumatic stress disorder should include a study of its application to Vietnam War Veterans in which improvements were observed on all variables, and several participants were able to return to work after several years of being unable to hold a job. The intervention has been studied for its impact on brain and autonomic nervous system function. It has been found to be highly effective against other stress-related conditions such as hypertension, and to improve brain coherence—a measure of effective brain function. It should be considered a possible ‘new and improved mode of treatment’ for PTSD, and further studies of its application made.

  14. Marginal fit of alumina-and zirconia-based fixed partial dentures produced by a CAD/CAM system.

    Science.gov (United States)

    Tinschert, J; Natt, G; Mautsch, W; Spiekermann, H; Anusavice, K J

    2001-01-01

    Clinical long-term success of all-ceramic dental restorations can be significantly influenced by marginal discrepancies. As a result, this in vitro study evaluated the marginal fit of alumina- and zirconia-based fixed partial dentures (FPDs) machined by the Precident DCS system. Different master steel models of three-, four- and five-unit posterior FPDs with an 0.8 mm chamfer preparation were produced. FPDs made of DC-Zirkon and In-Ceram Zirconia core ceramics were machined by the Precident DCS system. The marginal fit of the milled frameworks placed on the master steel models was determined by a replica technique using a light-body silicone to fill the discrepancies between crown and tooth and a heavy-body material to stabilize the light-body impression material. The impressions were poured into an epoxy resin material and each model was cross-sectioned with a low speed diamond saw to better visualize marginal discrepancies. The marginal fit of the FPDs was evaluated by scanning electron microscopy. The measurements of the marginal fit exhibited mean marginal discrepancies in a range between 60.5 and 74.0 microm, mean marginal gaps in a range from 42.9 to 46.3 microm, mean vertical discrepancies in a range from 20.9 to 48.0 microm and mean horizontal discrepancies in the range of 42.0 to 58.8 microm. Statistical data analysis was performed using the non-parametric test of Kruskal-Wallis and Mann-Whitney. The analysis revealed no significant differences (p>0.05) between the mean marginal gaps and vertical and horizontal discrepancies. However, for some FPDs the mean values of the marginal discrepancies were significantly different (p zirconia-based FPDs achieved with the Precident DCS system meet the clinical requirements.

  15. The effect of ceramic thickness and number of firings on the color of a zirconium oxide based all ceramic system fabricated using CAD/CAM technology.

    Science.gov (United States)

    Bachhav, Vinay Chila; Aras, Meena Ajay

    2011-06-01

    Ceramics have a long history in fixed prosthodontics for achieving optimal esthetics and various materials have been used to improve ceramic core strength. However, there is a lack of information on how color is affected by fabrication procedure. The purpose of this study was to evaluate the effects of various dentin ceramic thicknesses and repeated firings on the color of zirconium oxide all-ceramic system (Lava™) fabricated using CAD/CAM technology. Thirty disc-shaped cores, 12 mm in diameter with a 1 mm thickness were fabricated from zirconium oxide based all ceramic systems (Lava™, 3M ESPE, St Paul, MN, USA) and divided into three groups (n = 10) according to veneering with dentin ceramic thicknesses: as 0.5, 1, or 1.5 mm. Repeated firings (3, 5, 7, or 9) were performed, and the color of the specimens was compared with the color after the initial firing. Color differences among ceramic specimens were measured using a spectrophotometer (VITA Easyshade, VITA Zahnfabrik, Bad Säckingen, Germany) and data were expressed in CIELAB system coordinates. A repeated measures ANOVA and Bonferroni post hoc test were used to analyze the data (n = 10, α=.05). L*a*b* values of the ceramic systems were affected by the number of firings (3, 5, 7, or 9 firings) (PL*a*b* values between the number of firings and ceramic thickness (P<.001). An increase in number of firings resulted in significant increase in L* values for both 0.5 mm and 1.5 mm thicknesses (P<.01, P=.013); however it decreased for 1 mm thickness (P<.01). The a* values increased for 1 mm and 1.5 mm thicknesses (P<.01), while it decreased for 0.5 mm specimens. The b* values increased significantly for all thicknesses (P<.01, P=.022). As the dentin ceramic thickness increased, significant reductions in L* values (P<.01) were recorded. There were significant increases in both a* and b* values (P<.01) as the dentin ceramic thickness increased. The number of firings and dentin ceramic thickness have a definite

  16. Influence of CAD/CAM systems and cement selection on marginal discrepancy of zirconia-based ceramic crowns.

    Science.gov (United States)

    Martínez-Rus, Francisco; Suárez, María J; Rivera, Begoña; Pradíes, Guillermo

    2012-04-01

    To analyze the effect of ceramic manufacturing technique and luting cement selection on the marginal adaptation of zirconium oxide-based all-ceramic crowns. An extracted mandibular first premolar was prepared for a complete coverage restoration and subsequently duplicated 40 times in a liquid crystal polymer (LCP). All-ceramic crowns (n = 10) were fabricated on LCP models using the following systems: glass-infiltrated zirconia-toughened alumina (In-Ceram Zirconia) and yttrium cation-doped tetragonal zirconia polycrystals (In-Ceram YZ, Cercon, and Procera Zirconia). The restorations (n = 5) were cemented on their respective dies with glass-ionomer cement (Ketac Cem Aplicap) and resin cement (Panavia 21). The absolute marginal discrepancy of the crowns was measured before and after cementation by scanning electronic microscopy at 160 points along the circumferential margin. The data were analyzed using one-way ANOVA for repeated measures and for independent samples, Scheffé's multiple range post hoc test, and Student's t-test (alpha = 0.05). There were statistical differences in the mean marginal openings among the four all-ceramic systems before and after luting (P cementation values (P cement resulted in larger marginal discrepancies than glass-ionomer cement (P < 0.0001).

  17. Special Section: Complementary and Alternative Medicine (CAM): Low Back Pain and CAM

    Science.gov (United States)

    ... Home Current Issue Past Issues Special Section CAM Low Back Pain and CAM Past Issues / Winter 2009 Table of ... benefit from CAM treatment for conditions such as low back pain. Photo courtesy of Glenn Scimonelli "Oh, my aching ...

  18. Machinability of an experimental Ti-Ag alloy in terms of tool life in a dental CAD/CAM system.

    Science.gov (United States)

    Inagaki, Ryoichi; Kikuchi, Masafumi; Takahashi, Masatoshi; Takada, Yukyo; Sasaki, Keiichi

    2015-01-01

    Titanium is difficult to machine because of its intrinsic properties. In a previous study, the machinability of titanium was improved by alloying with silver. This study aimed to evaluate the durability of tungsten carbide burs after the fabrication of frameworks using a Ti-20%Ag alloy and titanium with a computer-aided design and computer-aided manufacturing system. There was a significant difference in attrition area ratio between the two metals. Compared with titanium, the ratio of the area of attrition of machining burs was significantly lower for the experimental Ti-20%Ag alloy. The difference in the area of attrition for titanium and Ti-20%Ag became remarkable with increasing number of machining operations. The results show that the same burs can be used for a longer time with Ti-20%Ag than with pure titanium. Therefore, in terms of tool life, the machinability of the Ti-20%Ag alloy is superior to that of titanium.

  19. 12 CFR 212.9 - Effect of Interlocks Act on Clayton Act.

    Science.gov (United States)

    2010-01-01

    ... MANAGEMENT OFFICIAL INTERLOCKS § 212.9 Effect of Interlocks Act on Clayton Act. The Board regards the provisions of the first three paragraphs of section 8 of the Clayton Act (15 U.S.C. 19) to have been... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Effect of Interlocks Act on Clayton Act. 212.9...

  20. Thyroid Disease and Complementary and Alternative Medicine (CAM)

    Science.gov (United States)

    ... Alternative Medicine in Thyroid Disease Complementary and Alternative Medicine in Thyroid Disease (CAM) WHAT IS COMPLEMENTARY AND ALTERNATIVE MEDICINE (CAM)? Complementary and Alternative Medicine (CAM) is defined ...

  1. Aquatic CAM photosynthesis: a brief history of its discovery

    Science.gov (United States)

    Keeley, Jon E.

    2014-01-01

    Aquatic CAM (Crassulacean Acid Metabolism) photosynthesis was discovered while investigating an unrelated biochemical pathway concerned with anaerobic metabolism. George Bowes was a significant contributor to this project early in its infancy. Not only did he provide me with some valuable perspectives on peer review rejections, but by working with his gas exchange system I was able to take our initial observations of diel fluctuations in malic acid to the next level, showing this aquatic plant exhibited dark CO2 uptake. CAM is universal in all aquatic species of the worldwide Lycophyta genus Isoetes and non-existent in terrestrial Isoetes. Outside of this genus aquatic CAM has a limited occurrence in three other families, including the Crassulaceae. This discovery led to fascinating adventures in the highlands of the Peruvian Andes in search of Stylites, a terrestrial relative of Isoetes. Stylites is a plant that is hermetically sealed from the atmosphere and obtains all of its carbon from terrestrial sources and recycles carbon through CAM. Considering the Mesozoic origin of Isoetes in shallow pools, coupled with the fact that aquatic Isoetes universally possess CAM, suggests the earliest evolution of CAM photosynthesis was most likely not in terrestrial plants.

  2. Gas exchange and leaf anatomy of a C3-CAM hybrid, Yucca gloriosa (Asparagaceae).

    Science.gov (United States)

    Heyduk, Karolina; Burrell, Nia; Lalani, Falak; Leebens-Mack, Jim

    2016-03-01

    While the majority of plants use the typical C3 carbon metabolic pathway, ~6% of angiosperms have adapted to carbon limitation as a result of water stress by employing a modified form of photosynthesis known as Crassulacean acid metabolism (CAM). CAM plants concentrate carbon in the cells by temporally separating atmospheric carbon acquisition from fixation into carbohydrates. CAM has been studied for decades, but the evolutionary progression from C3 to CAM remains obscure. In order to better understand the morphological and physiological characteristics associated with CAM photosynthesis, phenotypic variation was assessed in Yucca aloifolia, a CAM species, Yucca filamentosa, a C3 species, and Yucca gloriosa, a hybrid species derived from these two yuccas exhibiting intermediate C3-CAM characteristics. Gas exchange, titratable leaf acidity, and leaf anatomical traits of all three species were assayed in a common garden under well-watered and drought-stressed conditions. Yucca gloriosa showed intermediate phenotypes for nearly all traits measured, including the ability to acquire carbon at night. Using the variation found among individuals of all three species, correlations between traits were assessed to better understand how leaf anatomy and CAM physiology are related. Yucca gloriosa may be constrained by a number of traits which prevent it from using CAM to as high a degree as Y. aloifolia. The intermediate nature of Y. gloriosa makes it a promising system in which to study the evolution of CAM. © The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  3. Gas exchange and leaf anatomy of a C3–CAM hybrid, Yucca gloriosa (Asparagaceae)

    Science.gov (United States)

    Heyduk, Karolina; Burrell, Nia; Lalani, Falak; Leebens-Mack, Jim

    2016-01-01

    While the majority of plants use the typical C3 carbon metabolic pathway, ~6% of angiosperms have adapted to carbon limitation as a result of water stress by employing a modified form of photosynthesis known as Crassulacean acid metabolism (CAM). CAM plants concentrate carbon in the cells by temporally separating atmospheric carbon acquisition from fixation into carbohydrates. CAM has been studied for decades, but the evolutionary progression from C3 to CAM remains obscure. In order to better understand the morphological and physiological characteristics associated with CAM photosynthesis, phenotypic variation was assessed in Yucca aloifolia, a CAM species, Yucca filamentosa, a C3 species, and Yucca gloriosa, a hybrid species derived from these two yuccas exhibiting intermediate C3–CAM characteristics. Gas exchange, titratable leaf acidity, and leaf anatomical traits of all three species were assayed in a common garden under well-watered and drought-stressed conditions. Yucca gloriosa showed intermediate phenotypes for nearly all traits measured, including the ability to acquire carbon at night. Using the variation found among individuals of all three species, correlations between traits were assessed to better understand how leaf anatomy and CAM physiology are related. Yucca gloriosa may be constrained by a number of traits which prevent it from using CAM to as high a degree as Y. aloifolia. The intermediate nature of Y. gloriosa makes it a promising system in which to study the evolution of CAM. PMID:26717954

  4. Board and auditor interlocks and voluntary disclosure in annual reports

    NARCIS (Netherlands)

    Braam, G.J.M.; Borghans, L.

    2014-01-01

    Purpose – The purpose of this study is to explore whether interlock ties between the board of directors and the external auditors facilitate the cross-firm diffusion of voluntary disclosures in annual reports. Design/methodology/approach – Using a sample of 149 non-financial companies publicly

  5. Charging/Safety-Interlock Connection For Capacitor Bank

    Science.gov (United States)

    Rippel, Wally E.

    1990-01-01

    Electrically controlled mechanical interlock apparatus prevents connection of bank of capacitors to battery or other dc power supply until capacitors precharged to nearly full supply voltage. Precharge eliminates excessive inrush current, which damages capacitors, wires, or connectors. Circuit in apparatus also discharges capacitors after power turned off or capacitors disconnected from power supply.

  6. Understanding dental CAD/CAM for restorations--the digital workflow from a mechanical engineering viewpoint.

    Science.gov (United States)

    Tapie, L; Lebon, N; Mawussi, B; Fron Chabouis, H; Duret, F; Attal, J-P

    2015-01-01

    As digital technology infiltrates every area of daily life, including the field of medicine, so it is increasingly being introduced into dental practice. Apart from chairside practice, computer-aided design/computer-aided manufacturing (CAD/CAM) solutions are available for creating inlays, crowns, fixed partial dentures (FPDs), implant abutments, and other dental prostheses. CAD/CAM dental solutions can be considered a chain of digital devices and software for the almost automatic design and creation of dental restorations. However, dentists who want to use the technology often do not have the time or knowledge to understand it. A basic knowledge of the CAD/CAM digital workflow for dental restorations can help dentists to grasp the technology and purchase a CAM/CAM system that meets the needs of their office. This article provides a computer-science and mechanical-engineering approach to the CAD/CAM digital workflow to help dentists understand the technology.

  7. PRODUCT DATA MANAGEMENT DALAM KAITAN DENGAN CAD/CAM

    Directory of Open Access Journals (Sweden)

    Bernardo Nugroho Yahya

    2004-01-01

    Full Text Available The future industry is the one who can manage the information system. Today, communication technology and distributed system computerization already have the ability to implement system that able to exchange and share information between different users. Product Data Management (PDM is an up-to-date and excellent method on managing the exchange and share of information. PDM is able to integrate and manage data analyzing process and documentation of the related product component physically. By adjusting the CAD/CAM on certain condition, the PDM will function maximally by using the information based on STEP (Standard for the Exchange of Product Data model. This article will explain the relationship between PDM system and CAD/CAM on industry. Abstract in Bahasa Indonesia : Sistem informasi merupakan ujung tombak sebuah perusahaan yang unggul di masa depan. Komputerisasi dengan sistem yang terdistribusi dan teknologi komunikasi saat ini memiliki kemampuan untuk mengimplementasikan sistem yang dapat menukar dan men-share informasi antar user yang berbeda. Teknologi yang mendapat cukup perhatian luas dalam hal pertukaran dan sharing informasi ini adalah Product Data Management (PDM. PDM dapat mengintegrasikan dan mengatur proses pengolahan data dan dokumen teknik yang berhubungan dengan komponen fisik produk yang bersangkutan. PDM akan berfungsi maksimal apabila kesesuaian dengan CAD/CAM diatur sedemikian rupa, dihubungkan dengan informasi berbasiskan STEP (Standard for the Exchange of Product Data model. Artikel ini akan menjelaskan hubungan antara sistem PDM dengan CAD/CAM dalam industri. Kata kunci: PDM, Manajemen Data, CAD/CAM, STEP.

  8. Successful Transcatheter Embolization of Penetrating Aortic Ulcer Using Interlocking Detachable Coils

    International Nuclear Information System (INIS)

    Hama, Yukihiro; Kaji, Tatsumi; Iwasaki, Yoshie; Hinokiyama, Kazuhiro; Shimizu, Masafumi; Kusano, Shoichi

    2000-01-01

    A 54-year-old man with persistent chest pain was hospitalized for hypertension and DeBakey type IIIb aortic dissection. The false lumen of the dissection was almost completely thrombosed; however, a penetrating atherosclerotic ulcer (PAU) was observed 5 weeks later. At that time, we successfully embolized the PAU with a microcatheter and interlocking detachable coils (IDCs). The patient is well with no episodes of relapse in 20 months of follow-up. This case suggests the utility of the microcatheter and IDC system as an alternative to surgery

  9. JunoCam's Imaging of Jupiter

    Science.gov (United States)

    Orton, Glenn; Hansen, Candice; Momary, Thomas; Caplinger, Michael; Ravine, Michael; Atreya, Sushil; Ingersoll, Andrew; Bolton, Scott; Rogers, John; Eichstaedt, Gerald

    2017-04-01

    Juno's visible imager, JunoCam, is a wide-angle camera (58° field of view) with 4 color filters: red, green and blue (RGB) and methane at 889 nm, designed for optimal imaging of Jupiter's poles. Juno's elliptical polar orbit offers unique views of Jupiter's polar regions with spatial scales as good as 50 km/pixel. At closest approach ("perijove") the images have spatial scale down to ˜3 km/pixel. As a push-frame imager on a rotating spacecraft, JunoCam uses time-delayed integration to take advantage of the spacecraft spin to extend integration time to increase signal. Images of Jupiter's poles reveal a largely uncharted region of Jupiter, as nearly all earlier spacecraft except Pioneer 11 have orbited or flown by close to the equatorial plane. Poleward of 64-68° planetocentric latitude, Jupiter's familiar east-west banded structure breaks down. Several types of discrete features appear on a darker, bluish-cast background. Clusters of circular cyclonic spirals are found immediately around the north and south poles. Oval-shaped features are also present, ranging in size down to JunoCam's resolution limits. The largest and brightest features usually have chaotic shapes; animations over ˜1 hour can reveal cyclonic motion in them. Narrow linear features traverse tens of degrees of longitude and are not confined in latitude. JunoCam also detected optically thin clouds or hazes that are illuminated beyond the nightside ˜1-bar terminator; one of these detected at Perijove lay some 3 scale heights above the main cloud deck. Tests have been made to detect the aurora and lightning. Most close-up images of Jupiter have been acquired at lower latitudes within 2 hours of closest approach. These images aid in understanding the data collected by other instruments on Juno that probe deeper in the atmosphere. When Jupiter was too close to the sun for ground-based observers to collect data between perijoves 1 and 2, JunoCam took a sequence of routine images to monitor large

  10. IBD and Complementary and Alternative Medicine (CAM)

    Science.gov (United States)

    ... Alternative Medicine (CAM) Go Back Complementary and Alternative Medicine (CAM) Email Print + Share Crohn’s disease and ulcerative ... Energy Medicine, and Biologically-Based Practices. Mind-Body Medicine Mind-body medicine is a set of interventions ...

  11. Use of Complementary and Alternative Medicine (CAM as Part of the Oncological Treatment: Survey about Patients' Attitude towards CAM in a University-Based Oncology Center in Germany.

    Directory of Open Access Journals (Sweden)

    Kerstin A Kessel

    Full Text Available To understand if and which patients would be open-minded to Complementary and Alternative Medicine (CAM use parallel to their oncological treatment. Moreover, we sought to determine which methods are most accepted and which are the primary motivators to use CAM.We developed and anonymously conducted a questionnaire for patients in the oncology center (TU Munich. Questions focus on different CAM methods, previous experiences, and willingness to apply or use CAM when offered in a university-based setting.A total of 171 of 376 patients (37.4% women, 62.0% men, 0.6% unknown participated. This corresponds to a return rate of 45%. Median age was 64 years (17-87 years. Of all participants, 15.2% used CAM during their oncological therapy; 32.7% have used it in the past. The majority (81.9% was not using CAM during therapy; 55.5% have not used CAM in the past respectively. The analysis revealed a significant correlation between education and CAM use during therapy (r = 0.18; p = 0.02, and CAM use in the past (r = 0.17; p = 0.04. Of all patients using CAM during therapy, favored methods were food supplements (42.3%, vitamins/minerals (42.3%, massage (34.6%. Motivations are especially the reduction of side effect and stress, the positive effect of certain CAM-treatments on the immune system and tumor therapy. Results showed no difference between women and men. Most patients not having had any experience with CAM complain about the deficiency of information by their treating oncologist (31.4% as well as missing treatment possibilities (54.3%.Since many patients believe in study results demonstrating the efficacy of CAM, it stresses our task to develop innovative study protocols to investigate the outcomes of certain CAM on symptom reduction or other endpoints. Thus, prospective trials and innovative evidence-based treatment concepts to include CAM into high-end oncology is what patients demand and what a modern oncology center should offer.

  12. The detection of EpCAM

    NARCIS (Netherlands)

    Wit, De Sanne; Dalum, Van Guus; Lenferink, Aufried T.M.; Tibbe, Arjan G.J.; Hiltermann, T.J.N.; Groen, Harry J.M.; Rijn, Van C.J.M.; Terstappen, Leon W.M.M.

    2015-01-01

    EpCAM expressing circulating tumor cells, detected by CellSearch, are predictive of short survival in several cancers and may serve as a liquid biopsy to guide therapy. Here we investigate the presence of EpCAM+ CTC detected by CellSearch and EpCAM- CTC discarded by

  13. CAD/CAM produces dentures with improved fit.

    Science.gov (United States)

    Steinmassl, Otto; Dumfahrt, Herbert; Grunert, Ingrid; Steinmassl, Patricia-Anca

    2018-02-22

    Resin polymerisation shrinkage reduces the congruence of the denture base with denture-bearing tissues and thereby decreases the retention of conventionally fabricated dentures. CAD/CAM denture manufacturing is a subtractive process, and polymerisation shrinkage is not an issue anymore. Therefore, CAD/CAM dentures are assumed to show a higher denture base congruence than conventionally fabricated dentures. It has been the aim of this study to test this hypothesis. CAD/CAM dentures provided by four different manufacturers (AvaDent, Merz Dental, Whole You, Wieland/Ivoclar) were generated from ten different master casts. Ten conventional dentures (pack and press, long-term heat polymerisation) made from the same master casts served as control group. The master casts and all denture bases were scanned and matched digitally. The absolute incongruences were measured using a 2-mm mesh. Conventionally fabricated dentures showed a mean deviation of 0.105 mm, SD = 0.019 from the master cast. All CAD/CAM dentures showed lower mean incongruences. From all CAD/CAM dentures, AvaDent Digital Dentures showed the highest congruence with the master cast surface with a mean deviation of 0.058 mm, SD = 0.005. Wieland Digital Dentures showed a mean deviation of 0.068 mm, SD = 0.005, Whole You Nexteeth prostheses showed a mean deviation of 0.074 mm, SD = 0.011 and Baltic Denture System prostheses showed a mean deviation of 0.086 mm, SD = 0.012. CAD/CAM produces dentures with better fit than conventional dentures. The present study explains the clinically observed enhanced retention and lower traumatic ulcer-frequency in CAD/CAM dentures.

  14. A review of complementary and alternative medicine (CAM) by people with multiple sclerosis.

    Science.gov (United States)

    Olsen, Sherri A

    2009-01-01

    Multiple sclerosis (MS) is a chronic, unpredictable disease of the central nervous system without a known cure. Because of this, people with MS often seek complementary and alternative medicines (CAM) to manage their disease symptoms. The goal of this review article was to describe the use of CAM by individuals diagnosed with MS. Evidence was obtained by searching Medline (1950-2007), EBSCOhost and PubMed for studies relating CAM to MS. Results from the literature showed that people with MS reported that they used CAM from 27 to 100%. The major reasons for choosing CAM were as follows: conventional treatment was not effective, anecdotal reports of CAM's help, and doctor referral. The types of CAM reported by people with MS included exercise, vitamins, herbal and mineral supplements, relaxation techniques, acupuncture, cannabis and massage. The major symptoms treated by CAM as noted in the literature were pain, fatigue and stress. There is a need for further research to evaluate the effectiveness of CAM with MS patients and their application by occupational therapists. The limitation of this literature review was the low response rate in many of the surveys reported. 2009 John Wiley & Sons, Ltd

  15. Design of responsive materials using topologically interlocked elements

    International Nuclear Information System (INIS)

    Molotnikov, A; Gerbrand, R; Qi, Y; Simon, G P; Estrin, Y

    2015-01-01

    In this work we present a novel approach to designing responsive structures by segmentation of monolithic plates into an assembly of topologically interlocked building blocks. The particular example considered is an assembly of interlocking osteomorphic blocks. The results of this study demonstrate that the constraining force, which is required to hold the blocks together, can be viewed as a design parameter that governs the bending stiffness and the load bearing capacity of the segmented structure. In the case where the constraining forces are provided laterally using an external frame, the maximum load the assembly can sustain and its stiffness increase linearly with the magnitude of the lateral load applied. Furthermore, we show that the segmented plate with integrated shape memory wires employed as tensioning cables can act as a smart structure that changes its flexural stiffness and load bearing capacity in response to external stimuli, such as heat generated by the switching on and off an electric current. (paper)

  16. Interlocked intramedullary nailing for treatment of open femoral shaft fractures.

    Science.gov (United States)

    Baixauli, F; Baixauli, E J; Sánchez-Alepuz, E; Baixauli, F

    1998-05-01

    Twenty-eight patients with open femoral shaft fractures treated by reamed intramedullary nailing were reviewed retrospectively. Nine patients had Gustilo Grade I injuries; 14, Grade II; and five, Grade IIIA. Twenty cases had static locking, two cases had dynamic locking, and six cases were not locked. Average time to union was 20 weeks. The infection and nonunion rates were 0%. The data suggest that interlocked reamed intramedullary nailing is a safe treatment option for treating open femoral shaft fractures.

  17. External jig in the placement of distal interlocking screws | Ikem ...

    African Journals Online (AJOL)

    Retrograde (52.2%) was the commonest surgical approach used for femur. The main indication for SIGN interlocking surgery was recent fracture 77.8%. Open reduction 97.8% was the commonest method of reduction used. The mean±SD bone union time was 3.58±0.56 months and range 3-5 months. Distal screw insertion ...

  18. Fuel rod fixing system

    International Nuclear Information System (INIS)

    Christiansen, D.W.

    1982-01-01

    This is a reusable system for fixing a nuclear reactor fuel rod to a support. An interlock cap is fixed to the fuel rod and an interlock strip is fixed to the support. The interlock cap has two opposed fingers, which are shaped so that a base is formed with a body part. The interlock strip has an extension, which is shaped so that this is rigidly fixed to the body part of the base. The fingers of the interlock cap are elastic in bending. To fix it, the interlock cap is pushed longitudinally on to the interlock strip, which causes the extension to bend the fingers open in order to engage with the body part of the base. To remove it, the procedure is reversed. (orig.) [de

  19. Determinants of Board Interlocking in the Brazilian Capital Market

    Directory of Open Access Journals (Sweden)

    Flávio Ribeiro

    2016-10-01

    Full Text Available The objective in this article was to identify the main determinants of Board Interlocking in the Brazilian capital market. As the theoretical structure, the Agency theory and Corporate Governance, the Resource Dependence theory and the Board of Administrators and the Characteristics of Board Interlocking. The sample consists of 58 Brazilian companies that participate in the Bovespa Index (Ibovespa. An empirical analytic study was undertaken. With regard to the objectives, it is characterized as exploratory and, with regard to the procedures, a documentary research was undertaken. The data on the Boards of Administrators were collected from the Reference Forms available on the website of the São Paulo Stock Exchange (BM&FBOVESPA. The results found demonstrate the generalized presence of Board Interlocking in these companies, normally associated with four factors: (1 economic group formation; (2 governmental control; (3 formation of pension funds; and (4 presence of professionals with acknowledged market experience. The results also suggest that the first three factors give rise to long-lasting links and that these connections are hard to break. On the other hand, the links established through professionals with market experience tend to be more unstable because the presence of these professionals is highly demanded to serve on the board of different companies.

  20. Effects of Interlocking and Supporting Conditions on Concrete Block Pavements

    Science.gov (United States)

    Mahapatra, Geetimukta; Kalita, Kuldeep

    2018-02-01

    Concrete Block Paving (CBP) is widely used as wearing course in flexible pavements, preferably under light and medium vehicular loadings. Construction of CBP at site is quick and easy in quality control. Usually, flexible pavement design philosophy is followed in CBP construction, though it is structurally different in terms of small block elements with high strength concrete and their interlocking aspects, frequent joints and discontinuity, restrained edge etc. Analytical solution for such group action of concrete blocks under loading in a three dimensional multilayer structure is complex and thus, the need of conducting experimental studies is necessitated for extensive understanding of the load—deformation characteristics and behavior of concrete blocks in pavement. The present paper focuses on the experimental studies for load transfer characteristics of CBP under different interlocking and supporting conditions. It is observed that both interlocking and supporting conditions affect significantly on the load transfer behavior in CBP structures. Coro-lock block exhibits better performance in terms of load carrying capacity and distortion behavior under static loads. Plate load tests are performed over subgrade, granular sub-base (GSB), CBP with and without GSB using different block shapes. For an example case, the comparison of CBP with conventional flexible pavement section is also presented and it is found that CBP provides considerable benefit in terms of construction cost of the road structure.

  1. Achieving interlocking nails without using an image intensifier.

    Science.gov (United States)

    Ikem, Innocent C; Ogunlusi, Johnson D; Ine, Henry R

    2007-08-01

    Interlocking nails are commonly performed using an image intensifier. These are expensive and are not readily available in most resource-poor countries of the world. The aim of this study was to achieve interlocking nailing without the use of an image intensifier. This is a prospective descriptive analysis of 40 consecutive cases seen with shaft fractures of the humerus, femur, and tibia. Fracture fixation was done using Surgical Implant Generation Network (SIGN) nails. Forty limbs in 34 patients were studied. There were 12 females and 22 males, giving a ratio of 1:2. The mean age (years) was 35.75+/-13.16 and the range was 17-70 years. The studied bones were: humerus 10%, femur 65%, and tibia 25%. The fracture lines were: transverse 40%, oblique 15%, and communited 45%. Fracture grades were: closed 90%, grade I, 5%, grade II, 2.5%, and grade IIIA, 2.5%. Surgical approaches were: antegrade 62.5% and retrograde 37.5%. Indications for fixation were: recent fracture 92.5%, non-union 5%, and malunion 3%. Methods of reductions were: open 85% and closed 15%. The mean follow-up period (years) was 1.50+/-0.78. The union time averaged 3 months. Complication was mainly screw loosening due to severe osteoporoses in one case. It is, therefore, concluded that, with the aid of external jigs and slot finders, interlocking can be achieved without an image intensifier.

  2. Tune resonance phenomena in the SPS and machine protection via fast position interlocking

    Energy Technology Data Exchange (ETDEWEB)

    Baer, Tobias [CERN, Genf (Switzerland); Universitaet Hamburg (Germany); DESY, Hamburg (Germany); Wenninger, Joerg; Bogey, Thierry; Araujo Meleiro, Berta [CERN, Genf (Switzerland)

    2010-07-01

    The 6911 m long Super Proton Synchrotron (SPS) at CERN with a peak energy of 450 GeV is at the top of the LHC preaccelerator-complex. Apart from the LHC, the SPS is with the Tevatron the accelerator with the largest stored beam energy of up to 2.5 MJ. The SPS has a known vulnerability to fast equipment failures that led to an uncontrolled loss of a high intensity beam in 2008, which resulted in major damage of a main dipole. The beam loss was caused by a fast tune decrease towards an integer resonance. Simulations and distinct experimental studies provide clear understanding of the beam dynamics at different SPS tune resonances. Diverging closed orbit oscillations, dispersion explosion and increased beta-beating are the driving effects that lead to a complete beam loss in as little as 10 turns (230 {mu}s) after reaching the stop band of the resonance. Dedicated experiments of fast failures of the main power converters reveal that the current interlock systems with a delay of 7-12 ms are much too slow for an adequate machine protection. To counteract the vulnerability of the SPS, current research focuses on a new fast position interlock system which is planned to become operational in the first quarter of 2010.

  3. The Pleiotropic Role of L1CAM in Tumor Vasculature

    Directory of Open Access Journals (Sweden)

    Francesca Angiolini

    2017-01-01

    Full Text Available Angiogenesis, the formation of new vessels, is a key step in the development, invasion, and dissemination of solid tumors and, therefore, represents a viable target in the context of antitumor therapy. Indeed, antiangiogenic approaches have given promising results in preclinical models and entered the clinical practice. However, in patients, the results obtained so far with antiangiogenic drugs have not completely fulfilled expectations, especially because their effect has been transient with tumors developing resistance and evasion mechanisms. A better understanding of the mechanisms that underlie tumor vascularization and the functional regulation of cancer vessels is a prerequisite for the development of novel and alternative antiangiogenic treatments. The L1 cell adhesion molecule (L1CAM, a cell surface glycoprotein previously implicated in the development and plasticity of the nervous system, is aberrantly expressed in the vasculature of various cancer types. L1CAM plays multiple pro-angiogenic roles in the endothelial cells of tumor-associated vessels, thus emerging as a potential therapeutic target. In addition, L1CAM prevents the maturation of cancer vasculature and its inhibition promotes vessel normalization, a process that is thought to improve the therapeutic response of tumors to cytotoxic drugs. We here provide an overview on tumor angiogenesis and antiangiogenic therapies and summarize the current knowledge on the biological role of L1CAM in cancer vasculature. Finally, we highlight the clinical implications of targeting L1CAM as a novel antiangiogenic and vessel-normalizing approach.

  4. "Do-it-yourself": Vaccine rejection and complementary and alternative medicine (CAM).

    Science.gov (United States)

    Attwell, Katie; Ward, Paul R; Meyer, Samantha B; Rokkas, Philippa J; Leask, Julie

    2018-01-01

    In this article, we elucidate a symbiotic relationship between complementary and alternative medicine (CAM) and rejection of, or hesitancy towards, vaccination. In Fremantle, Western Australia, and Adelaide, South Australia, we conducted in-depth interviews from September 2013-December 2015 with 29 parents who had refused or delayed some or all of their children's vaccines. Our qualitative analysis found that for many, their do-it-yourself ethic and personal agency was enhanced by self-directed CAM use, alongside (sometimes informal) CAM practitioner instruction. Reifying 'the natural,' these parents eschewed vaccines as toxic and adulterating, and embraced CAM as a protective strategy for immune systems before, during and after illness. Users saw CAM as harm-free, and when it came to experiences that non-users might interpret as demonstrating CAM's ineffectiveness, they rationalised to the contrary. They also generally glossed over its profit motive. CAM emerged as part of an expert system countering Western medicine. CAM's faces were trusted and familiar, and its cottage capitalism appeared largely free from the taint of "Big Pharma." A few parents employed a scientific critique of CAM modalities - and a minority were dubious of its profit motive - but others rejected the epistemology underpinning biomedicine, framing CAM as a knowledge not poisoned by avarice; a wisdom whose very evidence-base (anecdote and history) was demeaned by an arrogant scientific process only permitting belief in that which could be quantified. However, all parents engaged with Western medicine for broken bones and, sometimes, medical diagnoses. Our analysis suggests that pro-vaccination health professionals, policymakers and information-providers seeking to address the role of CAM in vaccine rejection face significant challenges due to the epistemic basis of some parents' decisions. However, we make some suggestions for professional practice and policy to enhance trust in vaccination

  5. CAD/CAM generated all-ceramic primary telescopic prostheses.

    Science.gov (United States)

    Kurbad, A; Ganz, S; Kurbad, S

    2012-01-01

    Computer-aided design and manufacturing (CAD/CAM) systems have proven effective not only for the manufacture of crown and bridge frameworks, inlays, onlays and veneers, but also for the generation of all-ceramic primary telescopic prostheses in more than 10 years of use in dental technology. The new InLab 4.0 software generation makes it possible to design and mill primary telescopic prostheses with CAD/CAM technology. The computer-generated raw crowns for these restorations require very little manual adaptation. The secondary crowns are manufactured by electroforming and bonded onto the tertiary structure or framework.

  6. Traction Converting Substation from Viewpoint of Feeding Interlocking Plant at Czech Railwayes

    Directory of Open Access Journals (Sweden)

    Radovan Dolecek

    2004-01-01

    Full Text Available This paper presents analyses current and voltage harmonic in traction converting substation 3 kV. It researches their rise and influence to three-phase cable line 6 kV, 50 Hz that is used for feeding interlocking plant. Processing of this task is arisen from requirement practice for line Pěčky - Poříčany - Rostoklaty where happened to adverse ratio in particular transmission line of feeding system. It is meant especially about backward influence traction substation rectifier Pečky to three - phase cable line 6 kV, 50 Hz. At the determinate lenght of the cable line, when resonace frequency of circuit transformer 22 kV/6 kV and the cable line 6 kV, 50 Hz is approached frequency 550 Hz and 650 Hz (i.e. 11 and 13 harmonic are happened to socalled "annulations input reactance of this circuit". That is caused by the leakage of current resonace frequency from traction converting substation to cable line. That proceduces additional losses and deformation waveform of voltage too. This deformation can be reflected on how interlocking plant is working. 

  7. Bio-inspired ``jigsaw''-like interlocking sutures: Modeling, optimization, 3D printing and testing

    Science.gov (United States)

    Malik, I. A.; Mirkhalaf, M.; Barthelat, F.

    2017-05-01

    Structural biological materials such as bone, teeth or mollusk shells draw their remarkable performance from a sophisticated interplay of architectures and weak interfaces. Pushed to the extreme, this concept leads to sutured materials, which contain thin lines with complex geometries. Sutured materials are prominent in nature, and have recently served as bioinspiration for toughened ceramics and glasses. Sutures can generate large deformations, toughness and damping in otherwise all brittle systems and materials. In this study we examine the design and optimization of sutures with a jigsaw puzzle-like geometry, focusing on the non-linear traction behavior generated by the frictional pullout of the jigsaw tabs. We present analytical models which accurately predict the entire pullout response. Pullout strength and energy absorption increase with higher interlocking angles and for higher coefficients of friction, but the associated high stresses in the solid may fracture the tabs. Systematic optimization reveals a counter-intuitive result: the best pullout performance is achieved with interfaces with low coefficient of friction and high interlocking angle. We finally use 3D printing and mechanical testing to verify the accuracy of the models and of the optimization. The models and guidelines we present here can be extended to other types of geometries and sutured materials subjected to other loading/boundary conditions. The nonlinear responses of sutures are particularly attractive to augment the properties and functionalities of inherently brittle materials such as ceramics and glasses.

  8. The influence of biocalcification on soil-cement interlocking block compressive strength

    Directory of Open Access Journals (Sweden)

    Yoosathaporn, S.

    2015-01-01

    Full Text Available Description of the subject. Soil-cement interlocking block is used as the building block for many civil structures in Thailand. The addition of many alternative materials into interlocking block in order to improve compressive strength has been reported. However, there is currently no report on the influence of application of biocalcification or microbiologically induced calcite precipitation (MICP on interlocking block compressive strength. Objectives. This study aimed to investigate the effect of biocalcification on compressive strength of soil-cement interlocking block. Method. Soil bacterium, Bacillus pasteurii KCTC 3558, and Effective Microorganisms (EM were added into interlocking block before molding as the replacement of mixing water. The change of compressive strength in interlocking block at 3, 7, 14 and 28 days of incubation was determined. Results. At 28 days, the compressive strength of interlocking block supplemented with B. pasteurii KCTC 3558 and 5% EM were 7.38% and 9.79% significantly higher than control. Calcium carbonate crystals were also observed under scanning electron microscope which suggested that an increased compressive strength of interlocking block was caused by biocalcification. Conclusions. Our results showed that microbiologically induced calcite precipitation could help increasing the compressive strength of soil-cement interlocking block.

  9. A Hybrid RES Distributed Generation System for Autonomous Islands: A DER-CAM and Storage-Based Economic and Optimal Dispatch Analysis

    DEFF Research Database (Denmark)

    Michalitsakos, Panagiotis; Mihet-Popa, Lucian; Xydis, George

    2017-01-01

    The possibility of replacing the existing autonomous thermal power plants by Distributed Energy Resources (DER) based on renewable energy sources (RES), along with the appropriate energy storage technologies in order to deal with the major problems that autonomous islands usually face was investi......The possibility of replacing the existing autonomous thermal power plants by Distributed Energy Resources (DER) based on renewable energy sources (RES), along with the appropriate energy storage technologies in order to deal with the major problems that autonomous islands usually face......-CAM (Distributed Energy Resources Customer Adoption Model) decision support tool was used for the multi-objective analysis conducted, which proposes a set of optimal solutions defining the appropriate Distributed Generation (DG) technologies, the capacities of storage and other technologies and the optimal...

  10. D0 Central Tracking Solenoid Energization, Controls, Interlocks and Quench Protection Initial Validation Procedures

    International Nuclear Information System (INIS)

    Jaskierny, W.; Hance, R.

    1998-01-01

    This note presents the inspection and tests to be performed on the DZERO solenoid energization, controls, interlocks and quench protection system before it is energized for the first time. This test is to be performed with a 5000A jumper at the end of the bus instead of the solenoid. This system is based in DZERO room 511. A copy of this note shall be annotated, signed and dated by the person coordinating the procedure; and filed with the system maintenance records. Annotations shall include comments about any aspect of the procedure that is abnormal or unsuccessful. The following inspections and tests shall be performed by persons knowledgeable about the system. Each individual test step should be reviewed and understood before proceeding with that step.

  11. Marginal adaptation and CAD-CAM technology: A systematic review of restorative material and fabrication techniques.

    Science.gov (United States)

    Papadiochou, Sofia; Pissiotis, Argirios L

    2018-04-01

    The comparative assessment of computer-aided design and computer-aided manufacturing (CAD-CAM) technology and other fabrication techniques pertaining to marginal adaptation should be documented. Limited evidence exists on the effect of restorative material on the performance of a CAD-CAM system relative to marginal adaptation. The purpose of this systematic review was to investigate whether the marginal adaptation of CAD-CAM single crowns, fixed dental prostheses, and implant-retained fixed dental prostheses or their infrastructures differs from that obtained by other fabrication techniques using a similar restorative material and whether it depends on the type of restorative material. An electronic search of English-language literature published between January 1, 2000, and June 30, 2016, was conducted of the Medline/PubMed database. Of the 55 included comparative studies, 28 compared CAD-CAM technology with conventional fabrication techniques, 12 contrasted CAD-CAM technology and copy milling, 4 compared CAD-CAM milling with direct metal laser sintering (DMLS), and 22 investigated the performance of a CAD-CAM system regarding marginal adaptation in restorations/infrastructures produced with different restorative materials. Most of the CAD-CAM restorations/infrastructures were within the clinically acceptable marginal discrepancy (MD) range. The performance of a CAD-CAM system relative to marginal adaptation is influenced by the restorative material. Compared with CAD-CAM, most of the heat-pressed lithium disilicate crowns displayed equal or smaller MD values. Slip-casting crowns exhibited similar or better marginal accuracy than those fabricated with CAD-CAM. Cobalt-chromium and titanium implant infrastructures produced using a CAD-CAM system elicited smaller MD values than zirconia. The majority of cobalt-chromium restorations/infrastructures produced by DMLS displayed better marginal accuracy than those fabricated with the casting technique. Compared with copy

  12. Synthesis and analysis of coupler curves with combined planar cam ...

    African Journals Online (AJOL)

    user

    Abstract. Cam and follower mechanisms are widely used to convert a rotary input motion into a controlled reciprocating or oscillating motion as output in machines or robots. As this mechanism has an ability to provide unlimited variety of output motions. Many ..... Applying Newton's second law of motion to the system results.

  13. CAMS--A Think Tank for Global Ocean Problems.

    Science.gov (United States)

    Kaharl, Victoria A.

    1985-01-01

    The Center for the Analysis of Marine Systems (CAMS) was created as an interdisciplinary "think tank" to meet needs of modern oceanography. The international research center's focus and success rests on theory, observation, and computer modeling. Projects involving lava flow and year-to-year variations in abundance of fish are described. (DH)

  14. The application of CAD / CAM technology in Dentistry

    Science.gov (United States)

    Susic, I.; Travar, M.; Susic, M.

    2017-05-01

    Information and communication technologies have found their application in the healthcare sector, including the frameworks of modern dentistry. CAD / CAM application in dentistry is the process by which is attained finished dental restoration through fine milling process of ready ceramic blocks. CAD / CAM is an acronym of english words Computer-Aided-Design (CAD) / Computer-Aided-Manufacture (CAM), respectively dental computer aided design and computer aided manufacture of inlays, onlays, crowns and bridges. CAD / CAM technology essentially allows you to create a two-dimensional and three-dimensional models and their materialization by numerical controlled machines. In order to operate more efficiently, reduce costs, increase user/patient satisfaction and ultimately achieve profits, many dental offices in the world have their attention focused on implementation of modern IT solutions in everyday practice. In addition to the specialized clinic management software, inventory control, etc., or hardware such as the use of lasers in cosmetic dentistry or intraoral scanning, recently the importance is given to the application of CAD / CAM technology in the field of prosthetic. After the removal of pathologically altered tooth structure, it is necessary to achieve restoration that will be most similar to the anatomy of a natural tooth. Applying CAD / CAM technology on applicable ceramic blocks it can be obtained very quick, but also very accurate restoration, in the forms of inlays, onlays, bridges and crowns. The paper presents the advantages of using this technology as well as satisfaction of the patients and dentists by using systems as: Cercon, Celay, Cerec, Lava, Everest, which represent imperative of modern dentistry in creating fixed dental restorations.

  15. Method of sealing casings of subsurface materials management system

    Science.gov (United States)

    Nickelson, Reva A.; Richardson, John G.; Kostelnik, Kevin M.; Sloan, Paul A.

    2007-02-06

    Systems, components, and methods relating to subterranean containment barriers. Laterally adjacent tubular casings having male interlock structures and multiple female interlock structures defining recesses for receiving a male interlock structure are used to create subterranean barriers for containing and treating buried waste and its effluents. The multiple female interlock structures enable the barriers to be varied around subsurface objects and to form barrier sidewalls. The barrier may be used for treating and monitoring a zone of interest.

  16. A systematic meta-review of manipulative and body-based CAM for cancer

    DEFF Research Database (Denmark)

    Lunde, Anita; Johannessen, Helle

    another review warns against the use of massage for fragile patients. Conclusion: There is fairly good evidence that massage can help to reduce stress and anxiety in cancer patients if it is provided by well qualified practitioners. Massage can safely be combined with conventional cancer treatment......  Background: There is a need for high-level evidence on the effects of CAM for cancer. 36% of European cancer patients have used CAM, and CAM is increasing integrated in oncology without a firm evidence base. This presentation provides a meta review of effects of manipulative and body......-based complementary medicine for cancer. Methods: Pubmed, the Cochrane library, AMED and Science citation index were systematically searched for reviews of quantitative and qualitative studies on effects of CAM for cancer or cancer related systems published 2000-2007. All reviews on manipulative and body-based CAM...

  17. In Vitro Analysis of the Fracture Resistance of CAD/CAM Denture Base Resins

    Directory of Open Access Journals (Sweden)

    Otto Steinmassl

    2018-03-01

    Full Text Available Computer-aided design and computer-aided manufacturing (CAD/CAM denture base manufacturers claim to produce their resin pucks under high heat and pressure. Therefore, CAD/CAM dentures are assumed to have enhanced mechanical properties and, as a result, are often produced with lower denture base thicknesses than conventional, manually fabricated dentures. The aim of this study was to investigate if commercially available CAD/CAM denture base resins have more favourable mechanical properties than conventionally processed denture base resins. For this purpose, a series of three-point bending tests conforming to ISO specifications were performed on a total of 80 standardised, rectangular CAD/CAM denture base resin specimens from five different manufacturers (AvaDent, Baltic Denture System, Vita VIONIC, Whole You Nexteeth, and Wieland Digital Dentures. A heat-polymerising resin and an autopolymerising resin served as the control groups. The breaking load, fracture toughness, and the elastic modulus were assessed. Additionally, the fracture surface roughness and texture were investigated. Only one CAD/CAM resin showed a significantly increased breaking load. Two CAD/CAM resins had a significantly higher fracture toughness than the control groups, and all CAD/CAM resins had higher elastic moduli than the controls. Our results indicate that CAD/CAM denture base resins do not generally have better mechanical properties than manually processed resins. Therefore, the lower minimum denture base thicknesses should be regarded with some caution.

  18. In Vitro Analysis of the Fracture Resistance of CAD/CAM Denture Base Resins.

    Science.gov (United States)

    Steinmassl, Otto; Offermanns, Vincent; Stöckl, Wolfgang; Dumfahrt, Herbert; Grunert, Ingrid; Steinmassl, Patricia-Anca

    2018-03-08

    Computer-aided design and computer-aided manufacturing (CAD/CAM) denture base manufacturers claim to produce their resin pucks under high heat and pressure. Therefore, CAD/CAM dentures are assumed to have enhanced mechanical properties and, as a result, are often produced with lower denture base thicknesses than conventional, manually fabricated dentures. The aim of this study was to investigate if commercially available CAD/CAM denture base resins have more favourable mechanical properties than conventionally processed denture base resins. For this purpose, a series of three-point bending tests conforming to ISO specifications were performed on a total of 80 standardised, rectangular CAD/CAM denture base resin specimens from five different manufacturers (AvaDent, Baltic Denture System, Vita VIONIC, Whole You Nexteeth, and Wieland Digital Dentures). A heat-polymerising resin and an autopolymerising resin served as the control groups. The breaking load, fracture toughness, and the elastic modulus were assessed. Additionally, the fracture surface roughness and texture were investigated. Only one CAD/CAM resin showed a significantly increased breaking load. Two CAD/CAM resins had a significantly higher fracture toughness than the control groups, and all CAD/CAM resins had higher elastic moduli than the controls. Our results indicate that CAD/CAM denture base resins do not generally have better mechanical properties than manually processed resins. Therefore, the lower minimum denture base thicknesses should be regarded with some caution.

  19. Shutdown channels and fitted interlocks in atomic reactors

    International Nuclear Information System (INIS)

    Furet, J.; Landauer, C.

    1968-01-01

    This catalogue consists of tables (one per reactor) giving the following information: number and type of detectors, range of the shutdown channels, nature of the associated electronics, thresholds setting off the alarms, fitted interlocks. These cards have been drawn up with a view to an examination of the reactors safety by the 'Reactor Safety Sub-Commission', they take into account the latest decisions. The reactors involved in this review are: Azur, Cabri, Castor-Pollux, Cesar-Marius-2, Edf-2, EL3, EL4, Eole, G1, G2-G3, Harmonie, Isis, Masurca, Melusine, Minerve, Osiris, Pegase, Peggy, PAT, Rapsodie, SENA, Siloe, Siloette, Triton-Nereide, and Ulysse. (authors) [fr

  20. Stable three-dimensional metallic carbon with interlocking hexagons.

    Science.gov (United States)

    Zhang, Shunhong; Wang, Qian; Chen, Xiaoshuang; Jena, Puru

    2013-11-19

    Design and synthesis of 3D metallic carbon that is stable under ambient conditions has been a long-standing dream. We predict the existence of such phases, T6- and T14-carbon, consisting of interlocking hexagons. Their dynamic, mechanical, and thermal stabilities are confirmed by carrying out a variety of state-of-the-art theoretical calculations. Unlike the previously studied K4 and the simple cubic high pressure metallic phases, the structures predicted in this work are stable under ambient conditions. Equally important, they may be synthesized chemically by using benzene or polyacenes molecules.

  1. Photovoltaic module and interlocked stack of photovoltaic modules

    Science.gov (United States)

    Wares, Brian S.

    2014-09-02

    One embodiment relates to an arrangement of photovoltaic modules configured for transportation. The arrangement includes a plurality of photovoltaic modules, each photovoltaic module including a frame. A plurality of individual male alignment features and a plurality of individual female alignment features are included on each frame. Adjacent photovoltaic modules are interlocked by multiple individual male alignment features on a first module of the adjacent photovoltaic modules fitting into and being surrounded by corresponding individual female alignment features on a second module of the adjacent photovoltaic modules. Other embodiments, features and aspects are also disclosed.

  2. Emergent Strain Stiffening in Interlocked Granular Chains

    Science.gov (United States)

    Dumont, Denis; Houze, Maurine; Rambach, Paul; Salez, Thomas; Patinet, Sylvain; Damman, Pascal

    2018-02-01

    Granular chain packings exhibit a striking emergent strain-stiffening behavior despite the individual looseness of the constitutive chains. Using indentation experiments on such assemblies, we measure an exponential increase in the collective resistance force F with the indentation depth z and with the square root of the number N of beads per chain. These two observations are, respectively, reminiscent of the self-amplification of friction in a capstan or in interleaved books, as well as the physics of polymers. The experimental data are well captured by a novel model based on these two ingredients. Specifically, the resistance force is found to vary according to the universal relation log F ˜μ √{N }Φ11 /8z /b , where μ is the friction coefficient between two elementary beads, b is their size, and Φ is the volume fraction of chain beads when semidiluted in a surrounding medium of unconnected beads. Our study suggests that theories normally confined to the realm of polymer physics at a molecular level can be used to explain phenomena at a macroscopic level. This class of systems enables the study of friction in complex assemblies, with practical implications for the design of new materials, the textile industry, and biology.

  3. A roadmap for research on crassulacean acid metabolism (CAM) to enhance sustainable food and bioenergy production in a hotter, drier world.

    Science.gov (United States)

    Yang, Xiaohan; Cushman, John C; Borland, Anne M; Edwards, Erika J; Wullschleger, Stan D; Tuskan, Gerald A; Owen, Nick A; Griffiths, Howard; Smith, J Andrew C; De Paoli, Henrique C; Weston, David J; Cottingham, Robert; Hartwell, James; Davis, Sarah C; Silvera, Katia; Ming, Ray; Schlauch, Karen; Abraham, Paul; Stewart, J Ryan; Guo, Hao-Bo; Albion, Rebecca; Ha, Jungmin; Lim, Sung Don; Wone, Bernard W M; Yim, Won Cheol; Garcia, Travis; Mayer, Jesse A; Petereit, Juli; Nair, Sujithkumar S; Casey, Erin; Hettich, Robert L; Ceusters, Johan; Ranjan, Priya; Palla, Kaitlin J; Yin, Hengfu; Reyes-García, Casandra; Andrade, José Luis; Freschi, Luciano; Beltrán, Juan D; Dever, Louisa V; Boxall, Susanna F; Waller, Jade; Davies, Jack; Bupphada, Phaitun; Kadu, Nirja; Winter, Klaus; Sage, Rowan F; Aguilar, Cristobal N; Schmutz, Jeremy; Jenkins, Jerry; Holtum, Joseph A M

    2015-08-01

    Crassulacean acid metabolism (CAM) is a specialized mode of photosynthesis that features nocturnal CO2 uptake, facilitates increased water-use efficiency (WUE), and enables CAM plants to inhabit water-limited environments such as semi-arid deserts or seasonally dry forests. Human population growth and global climate change now present challenges for agricultural production systems to increase food, feed, forage, fiber, and fuel production. One approach to meet these challenges is to increase reliance on CAM crops, such as Agave and Opuntia, for biomass production on semi-arid, abandoned, marginal, or degraded agricultural lands. Major research efforts are now underway to assess the productivity of CAM crop species and to harness the WUE of CAM by engineering this pathway into existing food, feed, and bioenergy crops. An improved understanding of CAM has potential for high returns on research investment. To exploit the potential of CAM crops and CAM bioengineering, it will be necessary to elucidate the evolution, genomic features, and regulatory mechanisms of CAM. Field trials and predictive models will be required to assess the productivity of CAM crops, while new synthetic biology approaches need to be developed for CAM engineering. Infrastructure will be needed for CAM model systems, field trials, mutant collections, and data management. © 2015 ORNL/UT-Battelle New Phytologist © 2015 New Phytologist Trust.

  4. The path to CAM6: coupled simulations with CAM5.4 and CAM5.5

    Science.gov (United States)

    Bogenschutz, Peter A.; Gettelman, Andrew; Hannay, Cecile; Larson, Vincent E.; Neale, Richard B.; Craig, Cheryl; Chen, Chih-Chieh

    2018-01-01

    This paper documents coupled simulations of two developmental versions of the Community Atmosphere Model (CAM) towards CAM6. The configuration called CAM5.4 introduces new microphysics, aerosol, and ice nucleation changes, among others to CAM. The CAM5.5 configuration represents a more radical departure, as it uses an assumed probability density function (PDF)-based unified cloud parameterization to replace the turbulence, shallow convection, and warm cloud macrophysics in CAM. This assumed PDF method has been widely used in the last decade in atmosphere-only climate simulations but has never been documented in coupled mode. Here, we compare the simulated coupled climates of CAM5.4 and CAM5.5 and compare them to the control coupled simulation produced by CAM5.3. We find that CAM5.5 has lower cloud forcing biases when compared to the control simulations. Improvements are also seen in the simulated amplitude of the Niño-3.4 index, an improved representation of the diurnal cycle of precipitation, subtropical surface wind stresses, and double Intertropical Convergence Zone biases. Degradations are seen in Amazon precipitation as well as slightly colder sea surface temperatures and thinner Arctic sea ice. Simulation of the 20th century results in a credible simulation that ends slightly colder than the control coupled simulation. The authors find this is due to aerosol indirect effects that are slightly stronger in the new version of the model and propose a solution to ameliorate this. Overall, in these early coupled simulations, CAM5.5 produces a credible climate that is appropriate for science applications and is ready for integration into the National Center for Atmospheric Research's (NCAR's) next-generation climate model.

  5. 30 CFR 75.819 - Motor-starter enclosures; barriers and interlocks.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Motor-starter enclosures; barriers and...-Voltage Distribution High-Voltage Longwalls § 75.819 Motor-starter enclosures; barriers and interlocks. Compartment separation and cover interlock switches for motor-starter enclosures must be maintained in...

  6. 49 CFR 236.340 - Electromechanical interlocking machine; locking between electrical and mechanical levers.

    Science.gov (United States)

    2010-10-01

    ... between electrical and mechanical levers. 236.340 Section 236.340 Transportation Other Regulations... Electromechanical interlocking machine; locking between electrical and mechanical levers. In electro-mechanical interlocking machine, locking between electric and mechanical levers shall be maintained so that mechanical...

  7. Nonreamed interlocked intramedullary tibial nailing. One community's experience.

    Science.gov (United States)

    Duwelius, P J; Schmidt, A H; Rubinstein, R A; Green, J M

    1995-06-01

    Forty-nine acute displaced tibial fractures (31 closed, 18 open: 5 Grade I, 7 Grade II, 4 Grade IIIA, and 2 Grade IIIB) were treated in 1 community with a standard operative protocol using a distractor without a fracture table, and an unreamed interlocked tibial nail. Forty-six fractures healed (94%). Complications included 3 nonunions (6%), 2 deep infections (4%), 9 delayed unions (18%), 4 angular malunions (8%), 2 rotatory malunions (4%), and 12 interlocking screws bent or broke (24%). Twenty-eight patients (57%) required at least 1 additional operation to obtain union, most commonly dynamization of a statically locked nail. The authors conclude that unreamed tibial nails provide adequate stabilization of displaced tibial fractures and can be used in the management of most open or closed tibial fractures. However, static locking is required in axially unstable fractures. Early dynamization or exchange nailing and bone grafting should be considered to hasten union and avoid screw failure. The distractor is an excellent adjunctive technique for reduction and alignment of tibial shaft fractures during intramedullary nailing.

  8. Fracture Union in Closed Interlocking Nail in Femoral Fracture

    Directory of Open Access Journals (Sweden)

    R L Sahu

    2010-09-01

    Full Text Available INTRODUCTION: Fractures shaft femur is a major cause of morbidity and mortality in patients with lower extremity injuries. The objective of this study was to find out the outcome of Interlocking nail in fracture femur. METHODS: This study was conducted in the Department of Orthopaedic surgery in M. M. Medical College from July 2006 to November 2008. Seventy eight patients were recruited from Emergency and out patient department having closed fracture of femoral shaft. All patients were operated under general or spinal anesthesia. All patients were followed for nine months. RESULTS: Out of seventy eight patients, sixty nine patients underwent union in 90 to 150 days with a mean of 110.68 days. Touch down weight bearing was started on 2nd post-operative day. Complications found in four patients who had non-union, and five patients had delayed union which was treated with dynamization and bone graft. The results were excellent in 88.46% and good in 6.41% patients. CONCLUSIONS: We concluded that this technique is advantageous because of early mobilization (early weight bearing, less complication with good results and is economical. Keywords: close reamed interlocking nail, dynamization, femoral shaft fractures, union

  9. [Electromagnetic navigation interlocking intramedullary nail technology for treatment of femoral shaft fractures].

    Science.gov (United States)

    Zuo, Kangkang; Qin, Wei; Guo, Qing; Palati-Ababaikeli; Qiao, Peiliu; Shen, Mingquan; Yin, Lele; Pan, Qilin; Xu, Xiaoxiong

    2014-10-01

    To explore the value of electromagnetic navigation interlocking intramedullary nail in the treatment of femoral shaft fracture. Between July 2012 and October 2013, 53 cases of femoral shaft fracture were treated. There were 40 males and 13 females, aged 16-52 years (mean, 38.3 years). The causes of injury were traffic accident in 28 cases, falling from height in 11 cases, falling in 7 cases, crush injury in 4 cases, and other in 3 cases. Of 53 cases, there were 3 cases of open fracture (Gustilo I degree) and 50 cases of closed fracture. Fracture was located in the proximal femur in 17 cases, middle femur in 29 cases, and distal femur in 7 cases. According to Winquist classification, 7 cases were rated as type I, 8 cases as type II, 22 cases as type III, and 16 cases as type IV; according to AO classification, 18 cases were rated as type 32-A, 28 cases as type 32-B, and 7 cases as type 32-C. The time from injury to operation was 3-11 days (mean, 5 days). Distal interlocking intramedullary nail was implanted using electromagnetic navigation. The distal locking nail operation with interlocking intramedullary nail was successfully completed under electromagnetic navigation; the one-time success rate of distal locking nail operation reached 100%; and the locking nail time was 5.0-9.5 minutes (mean, 7.0 minutes). Healing of incision by first intention was obtained after operation, and no complication of skin necrosis, infection, and sinus tract occurred. Fifty-three cases were all followed up 5-12 months (mean, 9 months). One case had hip pain and weaken middle gluteal muscle strength, and the symptoms disappeared after removing the nail. During the follow-up period, no broken nails, nail exit, infection, or re-fracture occurred. All fractures achieved clinical healing, and the healing time was 8-22 weeks (mean, 14.5 weeks). In 49 patients followed up 8 months, the Lysholm score was excellent in 44 cases, good in 4 cases, and acceptable in 1 case, with an excellent and

  10. Hyper Suprime-Cam: Camera dewar design

    Science.gov (United States)

    Komiyama, Yutaka; Obuchi, Yoshiyuki; Nakaya, Hidehiko; Kamata, Yukiko; Kawanomoto, Satoshi; Utsumi, Yousuke; Miyazaki, Satoshi; Uraguchi, Fumihiro; Furusawa, Hisanori; Morokuma, Tomoki; Uchida, Tomohisa; Miyatake, Hironao; Mineo, Sogo; Fujimori, Hiroki; Aihara, Hiroaki; Karoji, Hiroshi; Gunn, James E.; Wang, Shiang-Yu

    2018-01-01

    This paper describes the detailed design of the CCD dewar and the camera system which is a part of the wide-field imager Hyper Suprime-Cam (HSC) on the 8.2 m Subaru Telescope. On the 1.°5 diameter focal plane (497 mm in physical size), 116 four-side buttable 2 k × 4 k fully depleted CCDs are tiled with 0.3 mm gaps between adjacent chips, which are cooled down to -100°C by two pulse tube coolers with a capability to exhaust 100 W heat at -100°C. The design of the dewar is basically a natural extension of Suprime-Cam, incorporating some improvements such as (1) a detailed CCD positioning strategy to avoid any collision between CCDs while maximizing the filling factor of the focal plane, (2) a spherical washers mechanism adopted for the interface points to avoid any deformation caused by the tilt of the interface surface to be transferred to the focal plane, (3) the employment of a truncated-cone-shaped window, made of synthetic silica, to save the back focal space, and (4) a passive heat transfer mechanism to exhaust efficiently the heat generated from the CCD readout electronics which are accommodated inside the dewar. Extensive simulations using a finite-element analysis (FEA) method are carried out to verify that the design of the dewar is sufficient to satisfy the assigned errors. We also perform verification tests using the actually assembled CCD dewar to supplement the FEA and demonstrate that the design is adequate to ensure an excellent image quality which is key to the HSC. The details of the camera system, including the control computer system, are described as well as the assembling process of the dewar and the process of installation on the telescope.

  11. ROLES OF INTERLOCKING DIRECTORATES IN AN EMERGING COUNTRY: CONTROL AND COORDINATION IN FAMILY BUSINESS GROUPS

    Directory of Open Access Journals (Sweden)

    Aylin Ataay

    2016-04-01

    Full Text Available Maman (1999 proposed that, in countries in which business groups are dominant forms for organizing economic activities, the interlocking directorate is a managerial tool that can be prioritized to control and coordinate activities of their affiliated firms within the same groups and align their business objectives. This organizational connection appears to be an intentional strategy on the part of the groups‟ headquarters. In order to study the interlocking ties in Turkish family business groups (FBG, this study focused on interlocking directorates among listed firms in Turkey. The findings of preliminary study reveal that almost all of the interlocking ties were within the business groups (BG in our sample. This is the result of assignment of familyaffiliated and/or professional inside directors to the various boards of companies in the BG. We also found that compare to vertical ties; business groups are using more horizontal interlocking connections to bond their affiliated companies together.

  12. The Hyper Suprime-Cam software pipeline

    Science.gov (United States)

    Bosch, James; Armstrong, Robert; Bickerton, Steven; Furusawa, Hisanori; Ikeda, Hiroyuki; Koike, Michitaro; Lupton, Robert; Mineo, Sogo; Price, Paul; Takata, Tadafumi; Tanaka, Masayuki; Yasuda, Naoki; AlSayyad, Yusra; Becker, Andrew C.; Coulton, William; Coupon, Jean; Garmilla, Jose; Huang, Song; Krughoff, K. Simon; Lang, Dustin; Leauthaud, Alexie; Lim, Kian-Tat; Lust, Nate B.; MacArthur, Lauren A.; Mandelbaum, Rachel; Miyatake, Hironao; Miyazaki, Satoshi; Murata, Ryoma; More, Surhud; Okura, Yuki; Owen, Russell; Swinbank, John D.; Strauss, Michael A.; Yamada, Yoshihiko; Yamanoi, Hitomi

    2018-01-01

    In this paper, we describe the optical imaging data processing pipeline developed for the Subaru Telescope's Hyper Suprime-Cam (HSC) instrument. The HSC Pipeline builds on the prototype pipeline being developed by the Large Synoptic Survey Telescope's Data Management system, adding customizations for HSC, large-scale processing capabilities, and novel algorithms that have since been reincorporated into the LSST codebase. While designed primarily to reduce HSC Subaru Strategic Program (SSP) data, it is also the recommended pipeline for reducing general-observer HSC data. The HSC pipeline includes high-level processing steps that generate coadded images and science-ready catalogs as well as low-level detrending and image characterizations.

  13. The Diamond machine protection system

    International Nuclear Information System (INIS)

    Heron, M.T.; Lay, S.; Chernousko, Y.; Hamadyk, P.; Rotolo, N.

    2012-01-01

    The Diamond Light Source Machine Protection System (MPS) manages the hazards from high power photon beams and other hazards to ensure equipment protection on the booster synchrotron and storage ring. The system has a shutdown requirement, on a beam mis-steer of under 1 msec and has to manage in excess of a thousand interlocks. This is realised using a combination of bespoke hardware and programmable logic controllers. The MPS monitors a large number of interlock signals from diagnostics instrumentation, vacuum instrumentation, photon front ends and plant monitoring subsystems. Based on logic it can then remove the source of the energy to ensure protection of equipment. Depending on requirements, interlocks are managed on a Local or a Global basis. The Global system is structured as two layers, and supports fast- and slow-response-time interlock requirements. A Global MPS module takes the interlock permits for a given interlock circuit from each of the cells of the accelerator, and, subject to all interlocks being good, produces a permit to operate the source of energy: the RF amplifier for vessel protection and the PSU for magnet protection. The Local MPS module takes fast Interlock inputs from one cell of the Storage Ring or one quadrant of the Booster. Fast interlocks are those that must drop the beam in under 400 μsec (the maximum speed of the interlock) in the event of failure. EPIC provides the user interface to the MPS system

  14. The role of complementary and alternative medicine (CAM in Germany – A focus group study of GPs

    Directory of Open Access Journals (Sweden)

    Rosemann Thomas

    2008-06-01

    Full Text Available Abstract Background There has been a marked increase in the use of complementary and alternative medicine (CAM in recent years worldwide. In Germany, apart from 'Heilpraktiker' (= state-licensed, non-medical CAM practitioners, some general practitioners (GPs provide CAM in their practices. This paper aims to explore the attitudes of GPs about the role of CAM in Germany, in relation to the healthcare system, quality of care, medical education and research. Furthermore, experiences of GPs integrating CAM in their daily practice were explored. Methods Using a qualitative methodological approach 3 focus groups with a convenience sample of 17 GPs were conducted. The discussions were transcribed verbatim and analysed using qualitative content analysis. Results The majority of the participating GPs had integrated one or more CAM therapies into their every-day practice. Four key themes were identified based on the topics covered in the focus groups: the role of CAM within the German healthcare system, quality of care, education and research. Within the theme 'role of CAM within the healthcare system' there were five categories: integration of CAM, CAM in the Statutory Health Insurance, modernisation of the Statutory Health Insurance Act, individual healthcare services and 'Heilpraktiker'. Regarding quality of care there were two broad groups of GPs: those who thought patients would benefit from standardizing CAM and those who feared that quality control would interfere with the individual approach of CAM. The main issues identified relating to research and education were the need for the development of alternative research strategies and the low quality of existing CAM education respectively. Conclusion The majority of the participating GPs considered CAM as a reasonable complementary approach within primary care. The study increased our understanding of GPs attitudes about the role of CAM within the German healthcare system and the use of

  15. Metacarpophalangeal joint of the thumb arthrodesis using intramedullary interlocking screws XMCP™.

    Science.gov (United States)

    Novoa-Parra, C N; Montaner-Alonso, D; Morales-Rodríguez, J

    2017-09-04

    The study objective was to assess the results of a thumb metacarpophalangeal joint (MCPJ) arthrodesis using intramedullary interlocking screws at 25°, XMCP ™ (Extremity Medical, Parsippany, NJ). Radiographs evaluated the angle of arthrodesis, time of fusion and fixation of the implant. Clinical and functional outcomes were assessed using the DASH questionnaire and the VAS scale. Any complications found during surgery or the follow-up period were noted. We studied 9 patients. The mean follow-up was 27.6 months. Patients showed clinical and radiological evidence of fusion in an average of 8 weeks, the angle of fusion was 25°. There were no complications and no implant had to be removed. The XMCP™ system provides a reliable method for MCPJ arthrodesis for several indications and can be used with other procedures in the complex hand. Copyright © 2017 SECOT. Publicado por Elsevier España, S.L.U. All rights reserved.

  16. Photoswitchable interlocked thiodiglycolamide as a cocatalyst of a chalcogeno-Baylis-Hillman reaction.

    Science.gov (United States)

    Martinez-Cuezva, Alberto; Saura-Sanmartin, Adrian; Nicolas-Garcia, Tomas; Navarro, Cristian; Orenes, Raul-Angel; Alajarin, Mateo; Berna, Jose

    2017-05-01

    En route to a photoswitchable interlocked catalyst we have proved the ability of thiodiglycolamide to act as a template in the formation of hydrogen-bonded [2]rotaxanes. X-ray diffraction studies reveal the shielding of the sulfide atom by the macrocycle. A series of molecular shuttles are described as having an isomerizable fumaramide and thiodiglycolamide binding sites for controlling the relative ring position at will. By employing these systems as photoregulated catalysts, the TiCl 4 -mediated chalcogeno-Morita-Baylis-Hillman reaction is tested. In the presence of the maleamide shuttle, in which the sulfide function is encapsulated by the macrocycle, a complete loss in control of the geometry of the produced aldol is observed. The E -aldol adduct is predominantly obtained when the photoisomerized fumaramide shuttle, in which the sulfide function is exposed, is used.

  17. A pH-Dependent, Mechanically Interlocked Switch: Organometallic [2]Rotaxane vs. Organic [3]Rotaxane.

    Science.gov (United States)

    Altmann, Philipp J; Pöthig, Alexander

    2017-12-04

    We present the first [2]rotaxane featuring a functional organometallic host. In contrast to the known organic scaffolds, this assembly shows a high post-synthetic modifiability. The reactivity of the Ag 8 pillarplex host is fully retained, as is exemplified by the first transmetalation in a rotaxane framework to provide the respective Au 8 analogue. Additionally, a transformation under acidic conditions to give a purely organic [3]rotaxane is demonstrated which is reversible upon addition of a suitable base, rendering the assembly a pH-dependent switch. Hereby, it is shown that the mechanically interlocked nature of the system enhances the kinetic stability of the NHC host complex by a factor of >1000 and corresponds to the first observation of a stabilizing "rotaxand effect". © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Report for fiscal 1998 on Simple Operation Type CAD/CAM System Development through International Cooperation. Report on the achievements of counterparts overseas; 1998 nendo 'kan'i sosagata denshi sekkei seian shien system no kaihatsu ni kansuru kenkyu kyoryoku' ni kansuru hokokusho. Kaigai counter part seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Concerning the subject matter, achievements of China, Indonesia, Malaysia, Singapore, and Thailand are reported. In China, a technical data transfer process is under development, designed to serve between CAD (computer-aided design)/CAM (computer-aided manufacturing) packages of different file formats. In Indonesia, WG1 activities are being conducted with the assistance of Toyota Motor Corporation, and WG3 activities with the assistance of Wacoal Corporation, Japan. In Malaysia, designing, development, and tests are under way for prototype systems of an electronic catalog, direct link to CAD/CAM, transfer and sharing of electronic manufacturing data, etc., all to be completed by March 1999. In Singapore, an electronic parts library is compiled, and a verification test is conducted involving response time, download time, etc. In Thailand, development is under way of an engineering browser, automobile industry-oriented WEB-based information center, etc. (NEDO)

  19. The Effect of Preparation Design on the Fracture Resistance of Zir-Conia Crown Copings (Computer Associated Design/Computer Associated Machine, CAD/CAM System

    Directory of Open Access Journals (Sweden)

    B. Atashkar

    2011-09-01

    Full Text Available Objective: One of the major problems of all ceramic restorations is their probable fracture against the occlusal force. The aim of the present in-vitro study is was to compare the effect of two marginal designs (chamfer & shoulder on the fracture resistance of zirconia copings, CERCON (CAD/CAM.MATERIALS AND METHODS: This in vitro study was done with single blind experimental technique. One stainless steel dye with 50’ chamfer finish line design (0.8 mm depth was prepared using milling machine. Ten epoxy resin dyes were made, The same dye was retrieved and 50' chamfer was converted into shoulder (1 mm.again ten epoxy resin dyes were made from shoulder dyes. Zirconia cores with 0.4 mm thickness and 35 µm cement Space fabricated on the20 epoxy resin dyes (10 samples chamfer and 10 samples shoulder in a dental laboratory. Then the zirconia cores were cemented on the epoxy resin dyes and underwent a fracture test with a universal testing machine (GOTECH AI-700LAC, Arson, USA and samples were investigated from the point of view of the origin of the failure.RESULT: The mean value of fracture resistance for shoulder margins were 788.90±99.56 N and for the chamfer margins were 991.75±112.00 N. The student’s T-test revealed a statistically significant difference between groups (P=0.001.CONCLUSION: The result of this study indicates that marginal design of the zirconia cores effects on their fracture resistance. A chamfer margin could improve the biomechanical performance of posterior single zirconia crown restorations. This may be because of strong unity and round internal angle in chamfer margin.

  20. Subsurface materials management and containment system, components thereof and methods relating thereto

    Science.gov (United States)

    Nickelson, Reva A.; Richardson, John G.; Kostelnik, Kevin M.; Sloan, Paul A.

    2006-04-18

    Systems, components, and methods relating to subterranean containment barriers. Laterally adjacent tubular casings having male interlock structures and multiple female interlock structures defining recesses for receiving a male interlock structure are used to create subterranean barriers for containing and treating buried waste and its effluents. The multiple female interlock structures enable the barriers to be varied around subsurface objects and to form barrier sidewalls. The barrier may be used for treating and monitoring a zone of interest.

  1. Comparative fracture strength analysis of Lava and Digident CAD/CAM zirconia ceramic crowns

    OpenAIRE

    Kwon, Taek-Ka; Pak, Hyun-Soon; Yang, Jae-Ho; Han, Jung-Suk; Lee, Jai-Bong; Kim, Sung-Hun; Yeo, In-Sung

    2013-01-01

    PURPOSE All-ceramic crowns are subject to fracture during function. To minimize this common clinical complication, zirconium oxide has been used as the framework for all-ceramic crowns. The aim of this study was to compare the fracture strengths of two computer-aided design/computer-aided manufacturing (CAD/CAM) zirconia crown systems: Lava and Digident. MATERIALS AND METHODS Twenty Lava CAD/CAM zirconia crowns and twenty Digident CAD/CAM zirconia crowns were fabricated. A metal die was also ...

  2. Complete Dentures Fabricated with CAD/CAM Technology and a Traditional Clinical Recording Method

    Directory of Open Access Journals (Sweden)

    Nadica Janeva

    2017-10-01

    Full Text Available The introduction of computer-aided design/computer-aided manufacturing (CAD/CAM technology into complete denture (CD fabrication ushered in a new era in removable prosthodontics. Commercially available CAD/CAM denture systems are expected to improve upon the disadvantages associated with conventional fabrication. The purpose of this report is to present the workflow involved in fabricating a CD with a traditional clinical recording method and CAD/CAM technology and to summarize the advantages to the dental practitioner and the patient.

  3. DYNAMIC ANALYSIS OF A CRIMPING DEVICE WITH MULTIPLE CAMS USING MSC ADAMS II

    Directory of Open Access Journals (Sweden)

    Gheorghe Popescu

    2012-05-01

    Full Text Available Through the present paper, the author presents the results of the dynamic analysis with MSC ADAMS of the mechanism with a crimping device with 12 tightening cams, designed and used in the technological process of assembly of the indigenous electrical detonators. In this sense, the mechanism with multiple cams is considered a mechanical system and is treated as an assembly of rigid bodies connected by mechanical connections and elastic elements. For shaping and simulation of the mechanism with multiple cams using ADAMS program, the author got through the following stages: construction of the pattern, its testing and simulation, validation, finishing, parametrization, optimization of the pattern.

  4. Complete Dentures Fabricated with CAD/CAM Technology and a Traditional Clinical Recording Method.

    Science.gov (United States)

    Janeva, Nadica; Kovacevska, Gordana; Janev, Edvard

    2017-10-15

    The introduction of computer-aided design/computer-aided manufacturing (CAD/CAM) technology into complete denture (CD) fabrication ushered in a new era in removable prosthodontics. Commercially available CAD/CAM denture systems are expected to improve upon the disadvantages associated with conventional fabrication. The purpose of this report is to present the workflow involved in fabricating a CD with a traditional clinical recording method and CAD/CAM technology and to summarize the advantages to the dental practitioner and the patient.

  5. Immediate CAD/ CAM Custom Fabricated Dental Implants

    Directory of Open Access Journals (Sweden)

    Jafar Kolahi

    2010-11-01

    Full Text Available Introduction: There will almost always be gaps between cylin-drical or screw shaped prefabricated implant surface and funnel-shaped tooth socket when an implant is placed immediately after tooth extraction. Hence expensive and difficult bone grafting is re-quired. A custom fabricated implant will be a pragmatic solution for this limitation.The hypothesis: First step following extraction of a tooth is data capture or scanning via a 3D scan method e.g. coordinate measuring machine or non-contact laser scanners such as triangulation range finder. Second step is reconstruction or modeling via editable CAD (computer-aided design model, allowing us to add retentive holes and correction of implant angle. Third step is fabrication via CAM (computer aided manufacturing followed by plasma cleaning process. Fourth step is insertion of the CAD/CAM custom fabricated one-stage implant in the fresh tooth socket. Optimal time for this step is 24-48 hours after extraction. The custom fabricated implant should not load 3-4 months. Usage of chlorhexidine mouth-rinse or chewing gum twice daily for 2 weeks and, in some cases oral antibiotic is recommended. Evaluation of the hypothesis: Contemporary dental implant system faced with several clinical and anatomical limitations such is low sinuses or nerve bundles. Complex and expensive surgical procedures such as nerve repositioning and sinus lift are frequently required. With custom fabricated implant we can overcome several of these limitations because insertion of custom fabricated implant will perform before alveolar bone recession.

  6. Transcript, protein and metabolite temporal dynamics in the CAM plant Agave.

    Science.gov (United States)

    Abraham, Paul E; Yin, Hengfu; Borland, Anne M; Weighill, Deborah; Lim, Sung Don; De Paoli, Henrique Cestari; Engle, Nancy; Jones, Piet C; Agh, Ryan; Weston, David J; Wullschleger, Stan D; Tschaplinski, Timothy; Jacobson, Daniel; Cushman, John C; Hettich, Robert L; Tuskan, Gerald A; Yang, Xiaohan

    2016-11-21

    Already a proven mechanism for drought resilience, crassulacean acid metabolism (CAM) is a specialized type of photosynthesis that maximizes water-use efficiency by means of an inverse (compared to C 3 and C 4 photosynthesis) day/night pattern of stomatal closure/opening to shift CO 2 uptake to the night, when evapotranspiration rates are low. A systems-level understanding of temporal molecular and metabolic controls is needed to define the cellular behaviour underpinning CAM. Here, we report high-resolution temporal behaviours of transcript, protein and metabolite abundances across a CAM diel cycle and, where applicable, compare the observations to the well-established C 3 model plant Arabidopsis. A mechanistic finding that emerged is that CAM operates with a diel redox poise that is shifted relative to that in Arabidopsis. Moreover, we identify widespread rescheduled expression of genes associated with signal transduction mechanisms that regulate stomatal opening/closing. Controlled production and degradation of transcripts and proteins represents a timing mechanism by which to regulate cellular function, yet knowledge of how this molecular timekeeping regulates CAM is unknown. Here, we provide new insights into complex post-transcriptional and -translational hierarchies that govern CAM in Agave. These data sets provide a resource to inform efforts to engineer more efficient CAM traits into economically valuable C 3 crops.

  7. Comparative fracture strength analysis of Lava and Digident CAD/CAM zirconia ceramic crowns

    Science.gov (United States)

    Kwon, Taek-Ka; Pak, Hyun-Soon; Han, Jung-Suk; Lee, Jai-Bong; Kim, Sung-Hun

    2013-01-01

    PURPOSE All-ceramic crowns are subject to fracture during function. To minimize this common clinical complication, zirconium oxide has been used as the framework for all-ceramic crowns. The aim of this study was to compare the fracture strengths of two computer-aided design/computer-aided manufacturing (CAD/CAM) zirconia crown systems: Lava and Digident. MATERIALS AND METHODS Twenty Lava CAD/CAM zirconia crowns and twenty Digident CAD/CAM zirconia crowns were fabricated. A metal die was also duplicated from the original prepared tooth for fracture testing. A universal testing machine was used to determine the fracture strength of the crowns. RESULTS The mean fracture strengths were as follows: 54.9 ± 15.6 N for the Lava CAD/CAM zirconia crowns and 87.0 ± 16.0 N for the Digident CAD/CAM zirconia crowns. The difference between the mean fracture strengths of the Lava and Digident crowns was statistically significant (Pzirconia crowns showed a complete fracture of both the veneering porcelain and the core whereas the Digident CAD/CAM zirconia crowns showed fracture only of the veneering porcelain. CONCLUSION The fracture strengths of CAD/CAM zirconia crowns differ depending on the compatibility of the core material and the veneering porcelain. PMID:23755332

  8. Compressibility effects on double tearing mode interlocking in differentially rotating plasmas

    International Nuclear Information System (INIS)

    Wang, Xian-Qu; Wang, Zheng-Xiong; Wei, Lai; Xu, Wen-Bin

    2012-01-01

    Effects of compressibility on the double tearing modes (DTMs) in rotating plasmas are numerically investigated by using a compressible magnetohydrodynamics (MHD) model. It is found that due to the compressibility effects, the threshold of the interlocking magnetic island width in the slow and intermediate rotation regimes is larger than the counterpart in the incompressible plasmas. In the fast rotation regime, the compressible effect makes the DTM islands interlock more easily and faster. Moreover, in the very fast rotation regime, the plasma rotation can more effectively suppress the DTM islands. The scalings of the interlocking threshold in the different rotation regimes are obtained. Effects of plasma viscosity and beta on the DTM interlocking in the compressible plasmas are also discussed. -- Highlights: ► The threshold of the interlocking island width is larger than the counterpart in the incompressible plasmas. ► Compressible effect makes the islands interlock more easily and faster. ► The plasma rotation can more effectively suppress the DTM islands in the very fast rotation regime. ► Plasma beta effect on DTM interlocking is discussed.

  9. CAM Photosynthesis in Submerged Aquatic Plants

    Science.gov (United States)

    Keeley, J.E.

    1998-01-01

    Crassulacean acid metabolism (CAM) is a CO2-concentrating mechanism selected in response to aridity in terrestrial habitats, and, in aquatic environments, to ambient limitations of carbon. Evidence is reviewed for its presence in five genera of aquatic vascular plants, including Isoe??tes, Sagittaria, Vallisneria, Crassula, and Littorella. Initially, aquatic CAM was considered by some to be an oxymoron, but some aquatic species have been studied in sufficient detail to say definitively that they possess CAM photosynthesis. CO2-concentrating mechanisms in photosynthetic organs require a barrier to leakage; e.g., terrestrial C4 plants have suberized bundle sheath cells and terrestrial CAM plants high stomatal resistance. In aquatic CAM plants the primary barrier to CO2 leakage is the extremely high diffusional resistance of water. This, coupled with the sink provided by extensive intercellular gas space, generates daytime CO2(Pi) comparable to terrestrial CAM plants. CAM contributes to the carbon budget by both net carbon gain and carbon recycling, and the magnitude of each is environmentally influenced. Aquatic CAM plants inhabit sites where photosynthesis is potentially limited by carbon. Many occupy moderately fertile shallow temporary pools that experience extreme diel fluctuations in carbon availability. CAM plants are able to take advantage of elevated nighttime CO2 levels in these habitats. This gives them a competitive advantage over non-CAM species that are carbon starved during the day and an advantage over species that expend energy in membrane transport of bicarbonate. Some aquatic CAM plants are distributed in highly infertile lakes, where extreme carbon limitation and light are important selective factors. Compilation of reports on diel changes in titratable acidity and malate show 69 out of 180 species have significant overnight accumulation, although evidence is presented discounting CAM in some. It is concluded that similar proportions of the aquatic

  10. Communities detection as a tool to assess a reform of the Italian interlocking directorship network

    Science.gov (United States)

    Drago, Carlo; Ricciuti, Roberto

    2017-01-01

    Interlocking directorships are important communication channels among companies and may have anticompetitive effect. A corporate governance reform was introduced in 2011 to prevent interlocking directorships in the financial sector. We apply community detection techniques to the analysis of the networks in 2009 and 2012 to ascertain the effect of such reform on the Italian directorship network. We find that, although the number of interlocking directorships decreases in 2012, the reduction takes place mainly at the periphery of the network. The network core is stable, allowing the most connected companies to keep their strategic position.

  11. The structure of the cytochrome P450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography

    NARCIS (Netherlands)

    Hiruma, Yoshitaka

    2014-01-01

    By utilizing paramagnetic NMR techniques, the structure and dynamics of the P450cam system were investigated. The analysis of PCS and RDC illuminated the stereo-specific final complex of Pdx and P450cam, while the results of PRE demonstrated the presence of a transient encounter complex.

  12. CAM Stochastic Volatility Model for Option Pricing

    Directory of Open Access Journals (Sweden)

    Wanwan Huang

    2016-01-01

    Full Text Available The coupled additive and multiplicative (CAM noises model is a stochastic volatility model for derivative pricing. Unlike the other stochastic volatility models in the literature, the CAM model uses two Brownian motions, one multiplicative and one additive, to model the volatility process. We provide empirical evidence that suggests a nontrivial relationship between the kurtosis and skewness of asset prices and that the CAM model is able to capture this relationship, whereas the traditional stochastic volatility models cannot. We introduce a control variate method and Monte Carlo estimators for some of the sensitivities (Greeks of the model. We also derive an approximation for the characteristic function of the model.

  13. Camshaft bearing arrangement for overhead cam engine

    Energy Technology Data Exchange (ETDEWEB)

    Yoshikawa, M.

    1985-01-01

    In an assembly for an internal combustion engine comprising a cylinder block, a cylinder head detachably affixed to the cylinder block by a plurality of threaded fastening means, a plurality of poppet valves supported for reciprocation in the cylinder head and a camshaft for operating the poppet valves, the improvement is described comprising a cam carrier detachably affixed to the cylinder head and overlying the threaded fastening means, and a bearing cap affixed to the cam carrier. The cam carrier and the bearing cap have bearing surfaces for journaling the camshaft.

  14. Understanding dental CAD/CAM for restorations--accuracy from a mechanical engineering viewpoint.

    Science.gov (United States)

    Tapie, Laurent; Lebon, Nicolas; Mawussi, Bernardin; Fron-Chabouis, Hélène; Duret, Francois; Attal, Jean-Pierre

    2015-01-01

    As is the case in the field of medicine, as well as in most areas of daily life, digital technology is increasingly being introduced into dental practice. Computer-aided design/ computer-aided manufacturing (CAD/CAM) solutions are available not only for chairside practice but also for creating inlays, crowns, fixed partial dentures (FPDs), implant abutments, and other dental prostheses. CAD/CAM dental practice can be considered as the handling of devices and software processing for the almost automatic design and creation of dental restorations. However, dentists who want to use dental CAD/CAM systems often do not have enough information to understand the variations offered by such technology practice. Knowledge of the random and systematic errors in accuracy with CAD/CAM systems can help to achieve successful restorations with this technology, and help with the purchasing of a CAD/CAM system that meets the clinical needs of restoration. This article provides a mechanical engineering viewpoint of the accuracy of CAD/ CAM systems, to help dentists understand the impact of this technology on restoration accuracy.

  15. Integration of CAM and CNC operation through code editing and manipulation

    International Nuclear Information System (INIS)

    Rosli Darmawan; Shalina Sheik Muhammad

    2004-01-01

    The IT technology for engineering design and manufacturing has gone through significant advancement for the last 30 years. It is widely acknowledged that IT would provide competitive advantage for engineering company in term of production cycle, productivity and efficiency. The recent development in this area is on the total system integration. While standard off-shelf CAD/CAM/CNC software and hardware packages would provide solution for system integration, more often than not users will stumble upon compatibility problems. Moreover, most of the integration deals with CAD and CAM systems. CNC integration has not been fully developed. Users always found problems in the integration of CAM and CNC machine due to the different level of technological development. CNC codes have not fundamentally progressed in the last 50 years, while CAD/CAM software packages have undergone massive evolution and improvement. This paper discusses a practical solution of CAM and CNC integration through code editing and manipulation within the CAM system in order to comply with the CNC machine requirements. (Author)

  16. Accuracy and safety of second-generation PillCam COLON capsule for colorectal polyp detection

    OpenAIRE

    Spada, Cristiano; De Vincentis, Fabio; Cesaro, Paola; Hassan, Cesare; Riccioni, Maria Elena; Minelli Grazioli, Leonardo; Bolivar, Santiago; Zurita, Andrade; Costamagna, Guido

    2012-01-01

    PillCam COLON capsule endoscopy (CCE) (Given Imaging Ltd, Yoqneam, Israel) is one of the most recent diagnostic, endoscopic technologies designed to explore the colon. CCE is a noninvasive, patient-friendly technique that is able to explore the colon without requiring sedation and air insufflation. The first generation of CCE was released onto the market in 2006 and although it generated great enthusiasm, it showed suboptimal accuracy. Recently, a second-generation system (PillCam COLON 2) (C...

  17. Particular purpose micro computers for an interlock system

    International Nuclear Information System (INIS)

    Valdovinos A, M.A.

    1981-01-01

    The use of a programmable controller for controlling an electron beam accelerator Pelletron type is proposed, the operating conditions of the electron beam accelerator are stated; a logic diagram elaborated and verified where those conditions are met is included, one traditional electric schematic diagram is made and one operational program is developed in programmable controller language, a modular control console is designed for the control operation. (author)

  18. Compositional Verification of Interlocking Systems for Large Stations

    DEFF Research Database (Denmark)

    Fantechi, Alessandro; Haxthausen, Anne Elisabeth; Macedo, Hugo Daniel dos Santos

    2017-01-01

    -network: in this way granting the access to a route is essentially a decision local to the sub-network, and the interfaces with the rest of the network easily abstract away less interesting details related to the external world. Following up on previous work, where we defined a compositional verification method...

  19. A Beam Interlock System for CERN High Energy Accelerators

    CERN Document Server

    Todd, Benjamin; Schmidt, R

    2006-01-01

    The Large Hadron Collider (LHC) at CERN (The European Organisation for Nuclear Research) is one of the largest and most complicated machines envisaged to date. The LHC has been conceived and designed over the course of the last 25 years and represents the cutting edge of accelerator technology with a collision energy of 14TeV, having a stored beam energy over 100 times more powerful than the nearest competitor. Commissioning of the machine is already nderway and operation with beam is intended for Autumn 2007, with 7TeV operation expected in 2008. The LHC is set to answer some of the fundemental questions in theoretical physics, colliding particles with such high energy that the inner workings of the quantum world can be revealed. Colliding particles together at such high energy makes very high demands on machine operation and protection. The specified beam energy requires strong magnetic fields that are made in superconducting dipole magnets, these magnets are kept only around two degrees above absolute zero...

  20. Do CAD/CAM dentures really release less monomer than conventional dentures?

    Science.gov (United States)

    Steinmassl, Patricia-Anca; Wiedemair, Verena; Huck, Christian; Klaunzer, Florian; Steinmassl, Otto; Grunert, Ingrid; Dumfahrt, Herbert

    2017-06-01

    Computer-aided design (CAD)/computer-aided manufacturing (CAM) dentures are assumed to have more favourable material properties than conventionally fabricated dentures, among them a lower methacrylate monomer release. The aim of this study was to test this hypothesis. CAD/CAM dentures were generated from ten different master casts by using four different CAD/CAM systems. Conventional, heat-polymerised dentures served as control group. Denture weight and volume were measured; the density was calculated, and the denture surface area was assessed digitally. The monomer release after 7 days of water storage was measured by high-performance liquid chromatography. Whole You Nexteeth and Wieland Digital Dentures had significantly lower mean volume and weight than conventional dentures. Baltic Denture System and Whole You Nexteeth had a significantly increased density. Baltic Denture System had a significantly smaller surface area. None of the CAD/CAM dentures released significantly less monomer than the control group. All tested dentures released very low amounts of methacrylate monomer, but not significantly less than conventional dentures. A statistically significant difference might nevertheless exist in comparison to other, less recommendable denture base materials, such as the frequently used autopolymerising resins. CAD/CAM denture fabrication has numerous advantages. It enables the fabrication of dentures with lower resin volume and lower denture weight. Both could increase the patient comfort. Dentures with higher density might exhibit more favourable mechanical properties. The hypothesis that CAD/CAM dentures release less monomer than conventional dentures could, however, not be verified.

  1. Model Documentation for the MiniCAM

    Energy Technology Data Exchange (ETDEWEB)

    Brenkert, Antoinette L.; Smith, Steven J.; Kim, Son H.; Pitcher, Hugh M.

    2003-07-17

    The MiniCAM, short for the Mini-Climate Assessment Model, is an integrated assessment model of moderate complexity focused on energy and agriculture sectors. The model produces emissions of greenhouse gases (carbon dioxide, methane and nitrous oxide) and other radiatively important substances such as sulfur dioxide. Through incorporation of the simple climate model MAGICC, the consequences of these emissions for climate change and sea-level rise can be examined. The MiniCAM is designed to be fast and flexible.

  2. Interlock recovery during the drying, calcination and vitrification phase of Am/Cm processing

    International Nuclear Information System (INIS)

    Snyder, T.K.

    2000-01-01

    This document summarizes the results of five CIM5 [5-inch Cylindrical Induction Melter] runs designed to demonstrate power interlock recovery methods during the drying, calcination and vitrification phases of the Am/Cm melter cycle

  3. 18 CFR 45.9 - Automatic authorization of certain interlocking positions.

    Science.gov (United States)

    2010-04-01

    ... owned, wholly or in part, by the other and, as its primary business, owns or operates transmission or... interlock involves affiliated public utilities. (b) Conditions of authorization. As a condition of...

  4. Washington State's alcohol ignition interlock law: effects on recidivism among first-time DUI offenders.

    Science.gov (United States)

    McCartt, Anne T; Leaf, William A; Farmer, Charles M; Eichelberger, Angela H

    2013-01-01

    To examine the effects of changes to Washington State's ignition interlock laws: moving issuance of interlock orders from courts to the driver licensing department in July 2003 and extending the interlock order requirement to first-time offenders with blood alcohol concentrations (BACs) below 0.15 percent ("first simple driving under the influence [DUI]") in June 2004. Trends in conviction types, interlock installation rates, and 2-year cumulative recidivism rates were examined for first-time convictions (simple, high-BAC, test refusal DUI; deferred prosecution; alcohol-related negligent driving) stemming from DUI arrests between January 1999 and June 2006. Regression analyses examined recidivism effects of the law changes and interlock installation rates. To examine general deterrent effects, trends in single-vehicle late-night crashes in Washington were compared with trends in California and Oregon. After the 2004 law change, the proportion of simple DUIs declined somewhat, though the proportion of negligent driving convictions (no interlock order requirement) continued an upward trend. Interlock installation rates for first simple DUIs were 3 to 6 percent in the year before the law change and one third after. Recidivism declined by an estimated 12 percent (e.g., expected 10.6% without law change vs. 9.3% among offenders arrested between April and June 2006, the last study quarter) among first simple DUI offenders and an estimated 11 percent (expected 10.2% vs. 9.1%) among all first-time offenders. There was an estimated 0.06 percentage point decrease in the recidivism rate for each percentage point increase in the proportion of first simple DUI offenders with interlocks. If installation rates had been 100 vs. 34 percent for first simple DUI offenders arrested between April and June 2006, and if the linear relationship between rates of recidivism and installations continued, recidivism could have been reduced from 9.3 to 5.3 percent. With installation rates of

  5. Statistical Shape Modeling of Cam Femoroacetabular Impingement

    Energy Technology Data Exchange (ETDEWEB)

    Harris, Michael D.; Dater, Manasi; Whitaker, Ross; Jurrus, Elizabeth R.; Peters, Christopher L.; Anderson, Andrew E.

    2013-10-01

    In this study, statistical shape modeling (SSM) was used to quantify three-dimensional (3D) variation and morphologic differences between femurs with and without cam femoroacetabular impingement (FAI). 3D surfaces were generated from CT scans of femurs from 41 controls and 30 cam FAI patients. SSM correspondence particles were optimally positioned on each surface using a gradient descent energy function. Mean shapes for control and patient groups were defined from the resulting particle configurations. Morphological differences between group mean shapes and between the control mean and individual patients were calculated. Principal component analysis was used to describe anatomical variation present in both groups. The first 6 modes (or principal components) captured statistically significant shape variations, which comprised 84% of cumulative variation among the femurs. Shape variation was greatest in femoral offset, greater trochanter height, and the head-neck junction. The mean cam femur shape protruded above the control mean by a maximum of 3.3 mm with sustained protrusions of 2.5-3.0 mm along the anterolateral head-neck junction and distally along the anterior neck, corresponding well with reported cam lesion locations and soft-tissue damage. This study provides initial evidence that SSM can describe variations in femoral morphology in both controls and cam FAI patients and may be useful for developing new measurements of pathological anatomy. SSM may also be applied to characterize cam FAI severity and provide templates to guide patient-specific surgical resection of bone.

  6. Chiropractic and CAM Utilization: A Descriptive Review

    Directory of Open Access Journals (Sweden)

    Meeker William C

    2007-01-01

    Full Text Available Abstract Objective To conduct a descriptive review of the scientific literature examining use rates of modalities and procedures used by CAM clinicians to manage chronic LBP and other conditions Data Sources A literature of PubMed and MANTIS was performed using the key terms Chiropractic; Low Back Pain; Utilization Rate; Use Rate; Complementary and Alternative Medicine; and Health Services in various combinations. Data Selection A total of 137 papers were selected, based upon including information about chiropractic utilization, CAM utilization and low back pain and other conditions. Data Synthesis Information was extracted from each paper addressing use of chiropractic and CAM, and is summarized in tabular form. Results Thematic analysis of the paper topics indicated that there were 5 functional areas covered by the literature: back pain papers, general chiropractic papers, insurance-related papers, general CAM-related papers; and worker's compensation papers. Conclusion Studies looking at chiropractic utilization demonstrate that the rates vary, but generally fall into a range from around 6% to 12% of the population, most of whom seek chiropractic care for low back pain and not for organic disease or visceral dysfunction. CAM is itself used by people suffering from a variety of conditions, though it is often used not as a primary intervention, but rather as an additional form of care. CAM and chiropractic often offer lower costs for comparable results compared to conventional medicine.

  7. Chiropractic and CAM utilization: a descriptive review.

    Science.gov (United States)

    Lawrence, Dana J; Meeker, William C

    2007-01-22

    To conduct a descriptive review of the scientific literature examining use rates of modalities and procedures used by CAM clinicians to manage chronic LBP and other conditions A literature of PubMed and MANTIS was performed using the key terms Chiropractic; Low Back Pain; Utilization Rate; Use Rate; Complementary and Alternative Medicine; and Health Services in various combinations. A total of 137 papers were selected, based upon including information about chiropractic utilization, CAM utilization and low back pain and other conditions. Information was extracted from each paper addressing use of chiropractic and CAM, and is summarized in tabular form. Thematic analysis of the paper topics indicated that there were 5 functional areas covered by the literature: back pain papers, general chiropractic papers, insurance-related papers, general CAM-related papers; and worker's compensation papers. Studies looking at chiropractic utilization demonstrate that the rates vary, but generally fall into a range from around 6% to 12% of the population, most of whom seek chiropractic care for low back pain and not for organic disease or visceral dysfunction. CAM is itself used by people suffering from a variety of conditions, though it is often used not as a primary intervention, but rather as an additional form of care. CAM and chiropractic often offer lower costs for comparable results compared to conventional medicine.

  8. A STUDY OF THE MANAGEMENT OF OPEN FRACTURES OF TIBIA BY UNREAMED INTERLOCKING NAIL

    OpenAIRE

    Kuppa Srinivas; Yerukala Ramana; Dema Rajaiah; Mohammad Akbar Khan; Sujith Omkaram; Venkateswar Reddy

    2015-01-01

    AIMS AND OBJECTIVES: To evaluate the results of closed interlocking intramedullary nailing without reaming in the treatment of open fractures of t he tibial shaft and study the difficulties (complications) encountered during the operative study. To compare the efficacy of interlocking intramedullary nailing without reaming in treating open fractures of tibia, Time required for the union of fracture, Range of motion of ankle and knee joint, Rate of malunion and mal rota...

  9. Radiation-free Insertion of Distal Interlocking Screw in Tibial and Femur Nailing: A Simple Technique

    OpenAIRE

    Soni, Ritesh Kumar; Mehta, Surender Mohan; Awasthi, Bhanu; Singh, Janith Lal; Kumar, Amit; Thakur, Lokesh; Tripathy, Sujit Kumar

    2012-01-01

    Background: Distal interlocking screw insertion in intramedullary nailing of long-bone fracture is a challenging task for orthopedic surgeons. It is difficult particularly when the surgeon is in his learning stage or when image intensifier is not available. We describe a radiation-free technique of distal interlocking screw insertion which is easy and practicable. Materials and Methods: In this technique, a same length nail is placed over the skin (outer nail) and through its distal-most scre...

  10. Governance of pension funds: interlocking and compensation of Australian superannuation fund boards

    OpenAIRE

    Ooi, Elizabeth Meishan

    2017-01-01

    This thesis documents the incidence and determinants of board interlocking (where directors simultaneously sit on multiple boards) in pension funds and examines its effect on fund performance. It also investigates the determinants of pension fund director compensation. The motivation to examine these issues stems from the distinctive interlocking and compensation practices in pension funds. Data on a sample of 249 Australian pension funds from 2004 to 2011 is collected from fund documents ...

  11. Compact Atomic Magnetometer for Global Navigation (NAV-CAM)

    Science.gov (United States)

    Bulatowicz, Michael; Larsen, Michael

    2014-05-01

    Northrop Grumman Navigation Systems Division is developing an atom-based magnetometer technology that has the potential for providing a global position reference independent of GPS. The NAV-CAM sensor is a direct outgrowth of the Nuclear Magnetic Resonance Gyro under development by the same technical team. It will be the only known magnetic field sensor capable of providing all 3 axes of magnetic vector direction and magnitude simultaneously with a whole-field scalar measurement, all within a single multi-axis sensing element measuring 4mm cube or smaller, essentially eliminating many of the problems encountered when using physically separate sensors or sensing elements. According to information presented by Ariyur et al. at the 2010 American Control Conference [1], the anticipated accuracy of 10 pico-Tesla (pT) and precision of <0.5 pT of the NAV-CAM sensor will enable magnetic determination of position with 20 meter accuracy and 1 meter resolution.

  12. GlastCam: A Telemetry-Driven Spacecraft Visualization Tool

    Science.gov (United States)

    Stoneking, Eric T.; Tsai, Dean

    2009-01-01

    Developed for the GLAST project, which is now the Fermi Gamma-ray Space Telescope, GlastCam software ingests telemetry from the Integrated Test and Operations System (ITOS) and generates four graphical displays of geometric properties in real time, allowing visual assessment of the attitude, configuration, position, and various cross-checks. Four windows are displayed: a "cam" window shows a 3D view of the satellite; a second window shows the standard position plot of the satellite on a Mercator map of the Earth; a third window displays star tracker fields of view, showing which stars are visible from the spacecraft in order to verify star tracking; and the fourth window depicts

  13. Strength properties of interlocking compressed earth brick units

    Science.gov (United States)

    Saari, S.; Bakar, B. H. Abu; Surip, N. A.

    2017-10-01

    This study presents a laboratory investigation on the properties of interlocking compressed earth brick (ICEB) units. Compressive strength, which is one of the most important properties in masonry structures, is used to determine masonry performance. The compressive strength of the ICEB units was determined by applying a compressive strength test for 340 units from four types of ICEB. To analyze the strength of the ICEB units, each unit was capped by a steel plate at the top and bottom to create a flat surface, and then ICEB was loaded until failure. The average compressive strength of the corresponding ICEB units are as follows: wall brick, 19.15 N/mm2; beam brick, 16.99 N/mm2; column brick, 13.18 N/mm2; and half brick, 11.79 N/mm2. All the ICEB units had compressive strength of over 5 N/mm2, which is the minimum strength for a load-bearing brick. This study proves that ICEB units may be used as load-bearing bricks. The strength of ICEBs is equal to that of other common bricks and blocks that are currently available in the market.

  14. Water absorption characteristic of interlocking compressed earth brick units

    Science.gov (United States)

    Bakar, B. H. Abu; Saari, S.; Surip, N. A.

    2017-10-01

    This study aims to investigate the water absorption characteristic of interlocking compressed earth brick (ICEB) units. Apart from compressive strength, water absorption is an important property in masonry. This property can affect the quality of the brick itself and the bond strength between the brick and mortar in masonry structures and can result in reducing its strength properties. The units were tested for 24 h water absorption and 5 h boiling water absorption. A total of 170 ICEB units from four ICEB types underwent both tests. For the 24 h water absorption, the ICEB units were dried in the oven for 24 h and then cooled before being weighed. Thereafter, each brick was immersed in water for 24 h and weighed. The same specimens used for the 24 h water absorption test were re-used for the 5 h boiling water absorption test. After completing the 24 h water absorption test, the brick was boiled for 5-hours and weighed. The highest water absorption for the ICEBs in the 24-hour water absorption and 5 h boiling water absorption tests are 15.09% and 17.18%, respectively. The half brick has the highest water absorption (15.87%), whereas the beam brick has the lowest (13.20%). The water absorption of an ICEB unit is higher than that of normal bricks, although the water absorption of the former remains below the maximum rate of the brick water absorption (21%).

  15. Interlocked by nanoscale sculpturing: pure aluminum copper contacts (Conference Presentation)

    Science.gov (United States)

    Gerngross-Baytekin, Melike; Gerngross, Mark Daniel; Carstensen, Jürgen; Adelung, Rainer

    2017-06-01

    Connecting metals reliable with different corrosion potential is a well-known challenge. An extreme example are copper aluminum contacts. Galvanic corrosion occurs if the two different metals are in contact with each other and an electrolyte, the aluminum becomes susceptible to corrosion under current flow. Usually, antioxidant pastes containing metals are employed but create difficulties e.g. for fatigue resistant power electronic connections. The recently described process of nanoscale sculpturing [1] offers an alternative. Usually, if the surface of metals like aluminium are prepared they are just arbitrary cuts through the bulk. There is no optimization of the surface grain structure towards stability at all. Neither the crystalline facets in the grains are in their most stable orientation nor is the protective oxide shell the most stable one. The nanoscale sculpturing approach is carving out the most stable grains and planes by chemical or electrochemical treatment. The decisive trick is that the chemistry is targeting towards the instable oxide and not the metal. Aluminium sample surfaces including alloys like AA575 exhibit afterwards single crystalline surface facets covered with nanoscale stable oxide films. Galvanically deposited copper forms extremely reliable interlocked connections on top, even allowing for soldering on top of their surface.

  16. Interlocking Corporate Directorates and the Global City Hierarchy

    Directory of Open Access Journals (Sweden)

    Jeffrey Kentor

    2015-08-01

    Full Text Available This paper examines the direct and indirect economic linkages of the most prominent cities in the world, those commonly referred to as “global cities”, in terms of the direct and indirect linkages of the boards of directors of Fortune Global 500 firms headquartered in a given city with boards of directors of other firms. Specifically, we identify the interlocks of corporate boards located within these major cities with other Fortune 500 boards of directors by degrees of separation, and present a new ranking for selected global cities based upon these direct and indirect ties. We find that New York clearly dominates these economic linkages, followed by London and Paris. This is most pronounced for financial companies. Contrary to other global city rankings, we locate Tokyo below Frankfurt and Chicago on this dimension. We argue that these multiple levels of indirect relationships reflect a significant, and until now unexplored, dimension of what it means to be a “global” city.

  17. Organometallic rotaxane dendrimers with fourth-generation mechanically interlocked branches

    Science.gov (United States)

    Wang, Wei; Chen, Li-Jun; Wang, Xu-Qing; Sun, Bin; Li, Xiaopeng; Zhang, Yanyan; Shi, Jiameng; Yu, Yihua; Zhang, Li; Liu, Minghua; Yang, Hai-Bo

    2015-01-01

    Mechanically interlocked molecules, such as catenanes, rotaxanes, and knots, have applications in information storage, switching devices, and chemical catalysis. Rotaxanes are dumbbell-shaped molecules that are threaded through a large ring, and the relative motion of the two components along each other can respond to external stimuli. Multiple rotaxane units can amplify responsiveness, and repetitively branched molecules—dendrimers—can serve as vehicles for assembly of many rotaxanes on single, monodisperse compounds. Here, we report the synthesis of higher-generation rotaxane dendrimers by a divergent approach. Linkages were introduced as spacer elements to reduce crowding and to facilitate rotaxane motion, even at the congested periphery of the compounds up to the fourth generation. The structures were characterized by 1D multinuclear (1H, 13C, and 31P) and 2D NMR spectroscopy, MALDI-TOF-MS, gel permeation chromatography (GPC), and microscopy-based methods including atomic force microscopy (AFM) and transmission electron microscopy (TEM). AFM and TEM studies of rotaxane dendrimers vs. model dendrimers show that the rotaxane units enhance the rigidity and reduce the tendency of these assemblies to collapse by self-folding. Surface functionalization of the dendrimers with ferrocenes as termini produced electrochemically active assemblies. The preparation of dendrimers with a well-defined topological structure, enhanced rigidity, and diverse functional groups opens previously unidentified avenues for the application of these materials in molecular electronics and materials science. PMID:25902491

  18. Ground-state thermodynamics of bistable redox-active donor-acceptor mechanically interlocked molecules.

    Science.gov (United States)

    Fahrenbach, Albert C; Bruns, Carson J; Cao, Dennis; Stoddart, J Fraser

    2012-09-18

    Fashioned through billions of years of evolution, biological molecular machines, such as ATP synthase, myosin, and kinesin, use the intricate relative motions of their components to drive some of life's most essential processes. Having control over the motions in molecules is imperative for life to function, and many chemists have designed, synthesized, and investigated artificial molecular systems that also express controllable motions within molecules. Using bistable mechanically interlocked molecules (MIMs), based on donor-acceptor recognition motifs, we have sought to imitate the sophisticated nanoscale machines present in living systems. In this Account, we analyze the thermodynamic characteristics of a series of redox-switchable [2]rotaxanes and [2]catenanes. Control and understanding of the relative intramolecular movements of components in MIMs have been vital in the development of a variety of applications of these compounds ranging from molecular electronic devices to drug delivery systems. These bistable donor-acceptor MIMs undergo redox-activated switching between two isomeric states. Under ambient conditions, the dominant translational isomer, the ground-state coconformation (GSCC), is in equilibrium with the less favored translational isomer, the metastable-state coconformation (MSCC). By manipulating the redox state of the recognition site associated with the GSCC, we can stimulate the relative movements of the components in these bistable MIMs. The thermodynamic parameters of model host-guest complexes provide a good starting point to rationalize the ratio of GSCC to MSCC at equilibrium. The bistable [2]rotaxanes show a strong correlation between the relative free energies of model complexes and the ground-state distribution constants (K(GS)). This relationship does not always hold for bistable [2]catenanes, most likely because of the additional steric and electronic constraints present when the two rings are mechanically interlocked with each other

  19. An in vitro comparison of vertical marginal gaps of CAD/CAM titanium and conventional cast restorations.

    Science.gov (United States)

    Tan, Philip L; Gratton, David G; Diaz-Arnold, Ana M; Holmes, David C

    2008-07-01

    To determine if there was a significant difference between the vertical marginal openings of cast restorations, computer-aided design, and computer-aided machining restorations. Ten working dies were created from a single master die and used to fabricate ten restorations in each of the following groups: computer-aided design/computer-assisted machining (CAD/CAM), WAX/CAM, and WAX/CAST. The CAD/CAM titanium restorations were fabricated using the scanning and crown design modules of the KaVo Everest system. The WAX/CAM titanium restorations were fabricated using the double scan technique with the KaVo Everest system. The WAX/CAST high noble copings were fabricated using the conventional lost wax casting technique. The restorations were seated on the master die, and high-resolution digital photographs were made of the marginal area on all four sides. The vertical marginal opening was then measured using a calibrated digital software program. One-way ANOVA and Tukey's post hoc tests were used to determine the presence of statistically significant differences. The vertical margin openings were CAD/CAM: 79.43 +/- 25.46 microm; WAX/CAM: 73.12 +/- 24.15 microm; WAX/CAST: 23.91 +/- 9.80 microm. There was a statistically significant difference between the WAX/CAST group and the remaining groups. There was no difference between the vertical marginal gaps of the CAD/CAM and WAX/CAM. The WAX/CAST technique resulted in smaller vertical marginal gaps than either CAD/CAM or WAX/CAM.

  20. Characterization of SynCAM surface trafficking using a SynCAM derived ligand with high homophilic binding affinity

    International Nuclear Information System (INIS)

    Breillat, Christelle; Thoumine, Olivier; Choquet, Daniel

    2007-01-01

    In order to better probe SynCAM function in neurons, we produced a fusion protein between the extracellular domain of SynCAM1 and the constant fragment of human IgG (SynCAM-Fc). Whether in soluble form or immobilized on latex microspheres, the chimera bound specifically to the surface of hippocampal neurons and recruited endogenous SynCAM molecules. SynCAM-Fc was also used in combination with Quantum Dots to follow the mobility of transfected SynCAM receptors at the neuronal surface. Both immobile and highly mobile SynCAM were found. Thus, SynCAM-Fc behaves as a high affinity ligand that can be used to study the function of SynCAM at the neuronal membrane

  1. The use of complementary alternative medicine (CAM) in 1 001 German adults: results of a population-based telephone survey.

    Science.gov (United States)

    Bücker, B; Groenewold, M; Schoefer, Y; Schäfer, T

    2008-01-01

    The objective of this study was to evaluate the patterns of use of complementary alternative medicine (CAM) in a representative adult population in Germany. A population-based telephone survey was conducted in Lübeck, Germany. We performed computer-assisted telephone interviews (CATI) in order to obtain information on demographics, health status, prevalence of CAM usage, motivation for using CAM, type of CAM and health problems for which CAM were used. 1,001 adults (median age 48 years) participated in the study (response 46.8%). 79.6% of the interviewed subjects reported health problems. The most frequently named problems were chronic pain (45.3%), circulation problems (32.9%) and colds with fever (27.8%). Non-users of CAM had a lower incidence (76.6%) of overall illness than users (83.5%) (OR 0.65, 0.47-0.89). 42.3% of the participants had used CAM. The CAM user group consisted of significantly more females (72.8 vs. 55.5%) (OR 2.32, 1.74-3.08) and involved better educated subjects (school education >12 years, 36.6 vs. 27.9%, OR 3.25, 1.35-7.81) than the non-user group. The main health problems for which CAM was used were chronic pain (36.3%), some cases of uncomplicated colds (16.9%) and for improving general health (14.7%). Three procedures accounted for the majority of usage: Acupuncture (34.5%), homeopathy (27.3%) and herbal medicine (9.7%). A large number of participants reported as the main reason for using CAM the wish to avoid drugs as much as possible (31.7%). 26.7% reported opting for CAM due to the recommendation of their physician. 23.9% gave unsatisfactory results of conventional medicine as reason for CAM usage. CAM is used widely for different complaints by the general population. This frequent use of CAM has implications for the health-care system and health policy.

  2. CAD/CAM from the graphic-design perspective

    Energy Technology Data Exchange (ETDEWEB)

    Marcus, A.

    1982-11-01

    CAD/CAM systems have evolved elaborate human-computer interfaces in order to facilitate the creation of highly detailed and specialized schematic diagrams and texts. Although these systems have powerful capacities in terms of graphics editing, data manipulation, and data storage, insufficient attention has been given to making the online interface (together with supporting documentation) user-friendly, i.e., understandable, memorable, and appealing to the general user. Graphic-design considerations in particular have been routinely overlooked. Graphic design concerns typography, symbol design, color, spatial layout, and temporal sequencing. Graphic design can assist computer science by providing insight and expertise in designing effective communication between human being and machine.

  3. Intramedullary nailing of femoral shaft fractures. Part III: Long-term effects of static interlocking fixation.

    Science.gov (United States)

    Brumback, R J; Ellison, T S; Poka, A; Bathon, G H; Burgess, A R

    1992-01-01

    The results of treatment of fractures of the femoral shaft with static interlocking nailing were reviewed retrospectively to determine the clinical importance of any stress-riser or stress-shielding properties of the nail. These properties, if relevant, would have been manifested by refracture of the femur, either through a hole used for a locking screw or through the original site of fracture after extraction of the device. Two hundred and fourteen fractures that had been treated with static interlocking nailing and that had healed without conversion to dynamic intramedullary fixation were divided into two groups. In Group I, which comprised 111 fractures, the static interlocking-fixation device was retained and in Group II, which comprised 103 fractures, the static interlocking-fixation device was removed during one operative procedure at an average of fourteen months after the injury. The average duration of follow-up was thirty months from the time of the original fixation in both groups. All patients in Group II were followed for a minimum of six months after removal of the nail. No femur in Group I, in which the static interlocked nail remained in situ, refractured. No femur in either group fractured through the proximal or the distal holes used for the locking screws. No locking screws or nails broke. One patient (1 per cent) in Group II had a refracture of the femoral shaft through the site of the original fracture six weeks after removal of the nail.(ABSTRACT TRUNCATED AT 250 WORDS)

  4. CAD-CAM plates versus conventional fixation plates for primary mandibular reconstruction: A biomechanical in vitro analysis.

    Science.gov (United States)

    Rendenbach, Carsten; Sellenschloh, Kay; Gerbig, Lucca; Morlock, Michael M; Beck-Broichsitter, Benedicta; Smeets, Ralf; Heiland, Max; Huber, Gerd; Hanken, Henning

    2017-11-01

    CAD/CAM reconstruction plates have become a viable option for mandible reconstruction. The aim of this study was to determine whether CAD/CAM plates provide higher fatigue strength compared with conventional fixation systems. 1.0 mm miniplates, 2.0 mm conventional locking plates (DePuy Synthes, Umkirch, Germany), and 2.0 mm CAD/CAM plates (Materialise, Leuven, Belgium/DePuy Synthes) were used to reconstruct a polyurethane mandible model (Synbone, Malans, CH) with cortical and cancellous bone equivalents. Mastication was simulated via cyclic dynamic testing using a universal testing machine (MTS, Bionix, Eden Prairie, MN, USA) until material failure reached a rate of 1 Hz with increasing loads on the left side. No significant difference was found between the groups until a load of 300 N. At higher loads, vertical displacement differed increasingly, with a poorer performance of miniplates (p = 0.04). Plate breakage occurred in miniplates and conventional locking plates. Screw breakage was recorded as the primary failure mechanism in CAD/CAM plates. Stiffness was significantly higher with the CAD/CAM plates (p = 0.04). CAD/CAM plates and reconstruction plates provide higher fatigue strength than miniplates, and stiffness is highest in CAD/CAM systems. All tested fixation methods seem sufficiently stable for mandible reconstruction. Copyright © 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  5. An Overview of Computer Aided Design/Computer Aided Manufacturing (CAD/CAM in Restorative Dentistry

    Directory of Open Access Journals (Sweden)

    Adil Abdullah

    2018-03-01

    Full Text Available Objective: To review the current knowledge of CAD/CAM in dentistry and its development in the mentioned field. Sources: An electronic search was conducted across Ovid Medline, complemented by manual search across individual databases, such as Cochrane, Medline and ISI Web of Science databases and Google Scholar for literature analysis on the mentioned topic. The studies were reviewed thoroughly. This paper summarizes the current scientific and clinical opinions through a brief overview regarding the preferred way of utilizing CAD/CAM in dentistry.  Conclusions: The importance of CAD/CAM systems has seen a dramatic development in the number of products and procedures over last decades, with a concomitant rise in publications on the topic. Literature suggests that using this technology permits carrying out dental treatments feasibly particularly for fixed dental appliances. Based on the previous findings, it is concluded that in office CAD/CAM technique appears to be the most common technique currently available, which is rapid, easy and keeps time. CAD/CAM systems are variable; therefore, using the right system with a logical approach for treating patients are quite mandatory.

  6. The Impact of Board Interlocks on Auditor Choice and Audit Fees

    DEFF Research Database (Denmark)

    Riise Johansen, Thomas; Pettersson, Kim

    2013-01-01

    Research Question/Issue This paper uses unique Danish data to examine whether non-executive directors draw on both direct and indirect ties in the network of interlocking directorates to impact auditor choice, and whether this impact has consequences for audit fees. Research Findings/Insight The ......Research Question/Issue This paper uses unique Danish data to examine whether non-executive directors draw on both direct and indirect ties in the network of interlocking directorates to impact auditor choice, and whether this impact has consequences for audit fees. Research Findings...... of the non-executive director–auditor relationship and the role that board networks have in governing auditor choice decisions. The study identifies interlocks as an infrastructure for differentiation in the audit market and determines that such differentiation is associated with an audit fee premium...

  7. Ulnar interlocking intramedullary nail stabilization of a proximal radio-ulnar fracture in a dog.

    Science.gov (United States)

    Gatineau, Matthieu; Planté, Jérôme

    2010-12-01

    To report use of an ulnar interlocking intramedullary nail for repair of an open highly comminuted fracture of the proximal third of the antebrachium in a dog, caused by gunshot. Case report. 1.5-year old, 60 kg, neutered male Mastiff. An ulnar interlocking intramedullary nail was used to stabilize an open comminuted proximal antebrachial fracture and a cast applied for 4 weeks. Union by secondary bone healing occurred in 8 weeks. At 16 weeks, there was advanced remodeling of the radial and ulnar bony callus and fracture lines were no longer evident. Limb use was normal with normal pain free range of motion of the right elbow. Ulnar interlocking nail is a viable alternative treatment for highly comminuted fracture of the proximal third of the antebrachium in dogs. © Copyright 2010 by The American College of Veterinary Surgeons.

  8. Poly[ n ]catenanes: Synthesis of molecular interlocked chains

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Qiong; Rauscher, Phillip M.; Lang, Xiaolong; Wojtecki, Rudy J.; de Pablo, Juan J.; Hore, Michael J. A.; Rowan, Stuart J.

    2017-11-30

    As the macromolecular version of mechanically interlocked molecules, mechanically interlocked polymers are promising candidates for the creation of sophisticated molecular machines and smart soft materials. Poly[n]catenanes, where the molecular chains consist solely of interlocked macrocycles, contain one of the highest concentrations of topological bonds. We report, herein, a synthetic approach toward this distinctive polymer architecture in high yield (similar to 75%) via efficient ring closing of rationally designed metallosupramolecular polymers. Light-scattering, mass spectrometric, and nuclear magnetic resonance characterization of fractionated samples support assignment of the high-molar mass product (number-average molar mass similar to 21.4 kilograms per mole) to a mixture of linear poly[7-26]catenanes, branched poly[13-130]catenanes, and cyclic poly[4-7]catenanes. Increased hydrodynamic radius (in solution) and glass transition temperature (in bulk materials) were observed upon metallation with Zn2+.

  9. Patients’ views of CAM as spiritual practice

    DEFF Research Database (Denmark)

    Ulrich, Anita; Evron, Lotte; Ostenfeld-Rosenthal, Ann

    2011-01-01

    significantly elaborated upon in narratives by four female participants to warrant more detailed consideration and analysis. Conclusion: It is suggested that for some cancer patients CAM may function, not just as a treatment for cancer related symptoms and side effects, but also as a form of spiritual practice...

  10. performance characteristics of a cam turning attachment

    African Journals Online (AJOL)

    Dr Obe

    cams on the lathe machine. To assess the performance of the attachment, cutting forces have been measured using a 'Sigma' Cutting Tool. Dynamometer. Furthermore, the effect of cutting parameters, such as, cutting speed, depth of cut and feed rate on the cutting forces, machining power and specific cutting energy have ...

  11. Faint stars and OmegaCAM

    NARCIS (Netherlands)

    Kuijken, K; Cristiani, S; Renzini, A; Williams, RE

    2001-01-01

    OmegaCAM will be the wide-field imager on the VLT Survey Telescope. In this contribution I present applications of this instrument to the study of faint stellar populations. Two projects are highlighted: a proper motion study to uncover the galactic halo population, and a microlensing study towards

  12. Prospective observation of CAD/CAM titanium ceramic single crowns: a three-year follow up.

    Science.gov (United States)

    Boeckler, Arne F; Lee, Heeje; Stadler, Anke; Setz, Jürgen M

    2009-11-01

    Computer-aided design/computer-aided manufacturing (CAD/CAM) titanium ceramic restorations were developed with the potential for replacing expensive, high noble metal ceramic restorations. However, there is a lack of information about the clinical performance of CAD/CAM titanium ceramic single crowns. The purpose of this study was to evaluate CAD/CAM titanium ceramic single crowns after 3 years in function. A total of 41 crowns were fabricated for 21 patients. The titanium copings were CAD/CAM milled (Everest CAD/CAM system) with an even thickness of 0.5 mm, and low-fusing veneering porcelain (Vita Titanium Porcelain) was added incrementally. The crowns were cemented using zinc phosphate cement after confirming that there were no mechanical and biological complications. The patients were recalled at 12, 24, and 36 months after cementation to examine the presence of any complications and measure periodontal parameters such as probing depth (PD), bleeding on probing (BOP), and plaque index (PI). The success and survival rates were estimated using the Kaplan-Meier analysis. The success rate of CAD/CAM titanium ceramic crowns with regard to mechanical complications was 82.3% (95% confidence interval: 71.2% to 95.1%). The cumulative survival rate of the crowns was 94.9% (95% confidence interval: 88.3% to 100%) after 3 years. No biological complications were observed. At the end of the follow up, PD was 2.93 mm, percentile of surface with BOP was 29.2, and PI was 0.31. The clinical performances of the CAD/CAM titanium ceramic crowns for 3 years were acceptable, with no biologic complications and a high cumulative survival rate.

  13. Design and fabrication of complete dentures using CAD/CAM technology.

    Science.gov (United States)

    Han, Weili; Li, Yanfeng; Zhang, Yue; Lv, Yuan; Zhang, Ying; Hu, Ping; Liu, Huanyue; Ma, Zheng; Shen, Yi

    2017-01-01

    The aim of the study was to test the feasibility of using commercially available computer-aided design and computer-aided manufacturing (CAD/CAM) technology including 3Shape Dental System 2013 trial version, WIELAND V2.0.049 and WIELAND ZENOTEC T1 milling machine to design and fabricate complete dentures.The modeling process of full denture available in the trial version of 3Shape Dental System 2013 was used to design virtual complete dentures on the basis of 3-dimensional (3D) digital edentulous models generated from the physical models. The virtual complete dentures designed were exported to CAM software of WIELAND V2.0.049. A WIELAND ZENOTEC T1 milling machine controlled by the CAM software was used to fabricate physical dentitions and baseplates by milling acrylic resin composite plates. The physical dentitions were bonded to the corresponding baseplates to form the maxillary and mandibular complete dentures.Virtual complete dentures were successfully designed using the software through several steps including generation of 3D digital edentulous models, model analysis, arrangement of artificial teeth, trimming relief area, and occlusal adjustment. Physical dentitions and baseplates were successfully fabricated according to the designed virtual complete dentures using milling machine controlled by a CAM software. Bonding physical dentitions to the corresponding baseplates generated the final physical complete dentures.Our study demonstrated that complete dentures could be successfully designed and fabricated by using CAD/CAM.

  14. Online visual inspection of self-piercing riveting to determine the quality of the mechanical interlock

    International Nuclear Information System (INIS)

    Johnson, P; Cullen, J D; Al-Shamma'a, A I; Shaw, A

    2007-01-01

    Self-piercing riveting (SPR) has become a significant joining technique for the automotive applications of aluminium sheets. Quality control in this locale has progressed at an altogether more leisurely rate than other areas of mechanical joining (e.g. spotweld) and is underdeveloped. Testing the quality mechanical interlock is often achieved by destructive testing, which results in material and time wastage. The solution is online monitoring of the self-piercing riveting process to provide non-destructive testing of the mechanical interlock. Introducing sensors into the process facilitates real time data acquisition, which can be used to determine the quality of the joint

  15. Complementary and alternative medicine use of women with breast cancer : Self-help CAM attracts other women than guided CAM therapies

    NARCIS (Netherlands)

    Lo-Fo-Wong, Deborah N. N.; Ranchor, Adelita V.; de Haes, Hanneke C. J. M.; Sprangers, Mirjam A. G.; Henselmans, Inge

    2012-01-01

    Objective: Examine stability of use of complementary and alternative medicine (CAM) of breast cancer patients, reasons for CAM use, and sociodemographic, clinical, and psychological predictors of CAM use. Methods: CAM use was assessed after adjuvant therapy and six months later. Following the CAM

  16. Complementary and alternative medicine use of women with breast cancer: Self-help CAM attracts other women than guided CAM therapies

    NARCIS (Netherlands)

    Lo-Fo-Wong, Deborah N. N.; Ranchor, Adelita V.; de Haes, Hanneke C. J. M.; Sprangers, Mirjam A. G.; Henselmans, Inge

    2012-01-01

    Objective: Examine stability of use of complementary and alternative medicine (CAM) of breast cancer patients, reasons for CAM use, and sociodemographic, clinical, and psychological predictors of CAM use. Methods: CAM use was assessed after adjuvant therapy and six months later. Following the CAM

  17. Complementary and alternative medicine use of women with breast cancer: self-help CAM attracts other women than guided CAM therapies.

    Science.gov (United States)

    Lo-Fo-Wong, Deborah N N; Ranchor, Adelita V; de Haes, Hanneke C J M; Sprangers, Mirjam A G; Henselmans, Inge

    2012-12-01

    Examine stability of use of complementary and alternative medicine (CAM) of breast cancer patients, reasons for CAM use, and sociodemographic, clinical, and psychological predictors of CAM use. CAM use was assessed after adjuvant therapy and six months later. Following the CAM Healthcare Model, CAM use was divided into use of provider-directed (guided) and self-directed (self-help) CAM. Stability and reasons for CAM use were examined with McNemar's tests and descriptive statistics. Cross-sectional and longitudinal associations between predictors and CAM use were examined with univariate and multivariate logistical analyses. Use of provider-directed and self-directed CAM was stable over time (N=176). Self-directed CAM was more often used to influence the course of cancer than provider-directed CAM. Both were used to influence well-being. Openness to experience predicted use of provider-directed CAM, while clinical distress predicted use of self-directed CAM, after adjusting for other predictors. Perceived control did not predict CAM use. CAM use is stable over time. It is meaningful to distinguish provider-directed from self-directed CAM. Providers are advised to plan a 'CAM-talk' before adjuvant therapy, and discuss patients' expectations about influence of CAM on the course of cancer. Distressed patients most likely need information about self-directed CAM. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  18. Detection of defects on the surface of a cam shaft using laser scattering method

    International Nuclear Information System (INIS)

    Dejima, S; Miyoshi, T; Takaya, Y; Maeno, Y

    2005-01-01

    This paper describes a new system to detect defects on the cam shafts of automobiles. The theory, based on laser scattering, is studied first, and then its feasibility is confirmed through basic experiments and simulations. Next, an inspection system is designed and built to verify the effectiveness of the method. The line laser, employed as a light source, illuminates the cam surface and its grey-scale image appears on a CCD as a white line, on which the missing part can be detected when there is a defect. The experimental results show that there is a big correlation between the size of the defect and the missing width. By scanning the laser over the entire surface of the cam shaft, the size and the shape of the defect was measured

  19. Optimal piston motion for maximum net output work of Daniel cam engines with low heat rejection

    International Nuclear Information System (INIS)

    Badescu, Viorel

    2015-01-01

    Highlights: • The piston motion of low heat rejection compression ignition engines is optimized. • A realistic model taking into account the cooling system is developed. • The optimized cam is smaller for cylinders without thermal insulation. • The optimized cam size depends on ignition moment and cooling process intensity. - Abstract: Compression ignition engines based on classical tapper-crank systems cannot provide optimal piston motion. Cam engines are more appropriate for this purpose. In this paper the piston motion of a Daniel cam engine is optimized. Piston acceleration is taken as a control. The objective is to maximize the net output work during the compression and power strokes. A major research effort has been allocated in the last two decades for the development of low heat rejection engines. A thermally insulated cylinder is considered and a realistic model taking into account the cooling system is developed. The sinusoidal approximation of piston motion in the classical tapper-crank system overestimates the engine efficiency. The exact description of the piston motion in tapper-crank system is used here as a reference. The radiation process has negligible effects during the optimization. The approach with no constraint on piston acceleration is a reasonable approximation. The net output work is much larger (by 12–13%) for the optimized system than for the classical tapper-crank system, for similar thickness of cylinder walls and thermal insulation. Low heat rejection measures are not of significant importance for optimized cam engines. The optimized cam is smaller for a cylinder without thermal insulation than for an insulated cylinder (by up to 8%, depending on the local polar radius). The auto-ignition moment is not a parameter of significant importance for optimized cam engines. However, for given cylinder wall and insulation materials there is an optimum auto-ignition moment which maximizes the net output work. The optimum auto

  20. Three-Dimensional Digital Evaluation of the Fit of Endocrowns Fabricated from Different CAD/CAM Materials.

    Science.gov (United States)

    Zimmermann, Moritz; Valcanaia, Andre; Neiva, Gisele; Mehl, Albert; Fasbinder, Dennis

    2018-03-06

    A wide variety of CAD/CAM materials are available for single-tooth restorations. CAD/CAM material characteristics are different and may influence CAM fabrication accuracy. There is no study investigating the influence of different CAD/CAM materials on the final fit of the restoration. The aim of this study was to evaluate the fit of endocrowns fabricated from different CAD/CAM materials using a new 3D evaluation method with an intraoral scanning system. The null hypothesis was that there are no significant differences for the fitting accuracy of different CAD/CAM materials. Preparation for an endocrown was performed on a maxillary right first molar on a typodont, and restorations were fabricated with a chairside CAD/CAM system (CEREC Omnicam, MCXL). Three groups using three different CAD/CAM materials were established (each n = 10): zirconia-reinforced lithium silicate ceramic (Celtra Duo; CD), leucite-reinforced silicate ceramic (Empress CAD; EM), resin nanoceramic (Lava Ultimate; LU). A 3D digital measurement technique (OraCheck, Cyfex AG) using an intraoral scanner (CEREC Omnicam) was used to measure the difference in fit between the three materials for a master endocrown preparation. The preparation scan and the endocrown fit scan were matched with special difference analysis software OraCheck. Three areas were selected for fitting accuracy measurements: margin (MA), axial (AX), occlusal (OC). Statistical analysis was performed using 80% percentile, one-way ANOVA, and post-hoc Scheffé test. Significance level was set to p = 0.05. Results varied from best 88.9 ± 7.7 μm for marginal fit of resin nanoceramic restorations (LU_MA) to worst 182.3 ± 24.0 μm for occlusal fit of zirconia-reinforced lithium silicate restorations (CD_OC). Statistically significant differences were found both within and among the test groups. Group CD performed statistically significantly different from group LU for marginal fit (MA) and axial fit (AX) (p 0.05). Deviation pattern for

  1. Introduction to Analytical Methods for Internal Combustion Engine Cam Mechanisms

    CERN Document Server

    Williams, J J

    2013-01-01

    Modern design methods of Automotive Cam Design require the computation of a range of parameters. This book provides a logical sequence of steps for the derivation of the relevant equations from first principles, for the more widely used cam mechanisms. Although originally derived for use in high performance engines, this work is equally applicable to the design of mass produced automotive and other internal combustion engines.   Introduction to Analytical Methods for Internal Combustion Engine Cam Mechanisms provides the equations necessary for the design of cam lift curves with an associated smooth acceleration curve. The equations are derived for the kinematics and kinetics of all the mechanisms considered, together with those for cam curvature and oil entrainment velocity. This permits the cam shape, all loads, and contact stresses to be evaluated, and the relevant tribology to be assessed. The effects of asymmetry on the manufacture of cams for finger follower and offset translating curved followers is ...

  2. Knowledge and training needs among Danish nurses about CAM

    DEFF Research Database (Denmark)

    Lunde, Anita

    2010-01-01

    to explore nurses’ knowledge about CAM and their needs for training. Methods: Similar to international investigations a Danish “CAM-knowledge” questionnaire was developed that included multiple choice, yes/no and 5 points scale answers. Validity was established through initial pilot testing. Contacts...... to a randomized sample of 2500 nurses were established through the Danish Nurses Foundation. The questionnaires were mailed by post with the possibility of anonymous return. The data material was analyzed using non-parametic methods. Results: The response rate was 67 % and 1458 completed questionnaires were...... of CAM also tend to have a theoretical background of CAM. Around 75 % of the nurses agree or partly agree that it is important for nurses to receive education about CAM and that nurses have knowledge about CAM that enables them to advise patients. Training needs concerning CAM were indicated by 52...

  3. Detection of EpCAM-Negative and Cytokeratin-Negative Circulating Tumor Cells in Peripheral Blood

    Directory of Open Access Journals (Sweden)

    Stephen D. Mikolajczyk

    2011-01-01

    Full Text Available Enrichment of rare circulating tumor cells (CTCs in blood is typically achieved using antibodies to epithelial cell adhesion molecule (EpCAM, with detection using cytokeratin (CK antibodies. However, EpCAM and CK are not expressed in some tumors and can be downregulated during epithelial-to-mesenchymal transition. A micro-fluidic system, not limited to EpCAM or CK, was developed to use multiple antibodies for capture followed by detection using CEE-Enhanced (CE, a novel in situ staining method that fluorescently labels the capture antibodies bound to CTCs. Higher recovery of CTCs was demonstrated using antibody mixtures compared to anti-EpCAM. In addition, CK-positive breast cancer cells were found in 15 of 24 samples (63%; range 1–60 CTCs, while all samples contained additional CE-positive cells (range 1–41; median = 11; =.02. Thus, antibody mixtures against a range of cell surface antigens enables capture of more CTCs than anti-EpCAM alone and CE staining enables the detection of CK-negative CTCs.

  4. Comparative characterization of a novel cad-cam polymer-infiltrated-ceramic-network.

    Science.gov (United States)

    Albero, Alberto; Pascual, Agustín; Camps, Isabel; Grau-Benitez, María

    2015-10-01

    The field of dental ceramics for CAD-CAM is enriched with a new innovative material composition having a porous three-dimensional structure of feldspathic ceramic infiltrated with acrylic resins.The aim of this study is to determine the mechanical properties of Polymer-Infiltrated-Ceramic-Network (PICN) and compare its performance with other ceramics and a nano-ceramic resin available for CAD-CAM systems. In this study a total of five different materials for CAD-CAM were investigated. A polymer-infiltrated ceramic (Vita Enamic), a nano-ceramic resin (Lava Ultimate), a feldspathic ceramic (Mark II), a lithium disilicate ceramic (IPS-e max CAD) and finally a Leucite based ceramic (Empress - CAD). From CAD-CAM blocks, 120 bars (30 for each material cited above) were cut to measure the flexural strength with a three-point-bending test. Strain at failure, fracture stress and Weibull modulus was calculated. Vickers hardness of each material was also measured. IPS-EMAX presents mechanical properties significantly better from the other materials studied. Its strain at failure, flexural strength and hardness exhibited significantly higher values in comparison with the others. VITA ENAMIC and LAVA ULTIMATE stand out as the next most resistant materials. The flexural strength, elastic modulus similar to a tooth as well as having less hardness than ceramics make PICN materials an option to consider as a restorative material. Ceramic infiltrated with resin, CAD-CAM, Weibull modulus, flexural strength, micro hardness.

  5. Ca2+-sensors and ROS-GC: Interlocked sensory transduction elements: A review

    Directory of Open Access Journals (Sweden)

    Rameshwar K Sharma

    2012-04-01

    Full Text Available From its initial discovery that ROS-GC membrane guanylate cyclase is a mono-modal Ca2+-transduction system linked exclusively with the phototransduction machinery to the successive finding that it embodies a remarkable bimodal Ca2+signaling device, its widened transduction role in the general signaling mechanisms of the sensory neuron cells was envisioned. A theoretical concept was proposed where Ca2+-modulates ROS-GC through its generated cyclic GMP via a nearby cyclic nucleotide gated channel and creates a hyper- or depolarized sate in the neuron membrane (Ca2+ Binding Proteins 1:1, 7-11, 2006. The generated electric potential then becomes a mode of transmission of the parent [Ca2+]i signal. Ca2+ and ROS-GC are interlocked messengers in multiple sensory transduction mechanisms.This comprehensive review discusses the developmental stages to the present status of this concept and demonstrates how neuronal Ca2+-sensor proteins are the interconnected elements of this elegant ROS-GC transduction system. The focus is on the dynamism of the structural composition of this system, and how it accommodates selectivity and elasticity for the Ca2+ signals to perform multiple tasks linked with the SENSES of vision, smell and possibly of taste and the pineal gland. An intriguing illustration is provided for the Ca2+ sensor GCAP1 which displays its remarkable ability for its flexibility in function from being a photoreceptor sensor to an odorant receptor sensor. In doing so it reverses its function from an inhibitor of ROS-GC to the stimulator of ONE-GC membrane guanylate cyclase.

  6. Fatigue resistance of CAD/CAM resin composite molar crowns.

    Science.gov (United States)

    Shembish, Fatma A; Tong, Hui; Kaizer, Marina; Janal, Malvin N; Thompson, Van P; Opdam, Niek J; Zhang, Yu

    2016-04-01

    To demonstrate the fatigue behavior of CAD/CAM resin composite molar crowns using a mouth-motion step-stress fatigue test. Monolithic leucite-reinforced glass-ceramic crowns were used as a reference. Fully anatomically shaped monolithic resin composite molar crowns (Lava Ultimate, n=24) and leucite reinforced glass-ceramic crowns (IPS Empress CAD, n=24) were fabricated using CAD/CAM systems. Crowns were cemented on aged dentin-like resin composite tooth replicas (Filtek Z100) with resin-based cements (RelyX Ultimate for Lava Ultimate or Multilink Automix for IPS Empress). Three step-stress profiles (aggressive, moderate and mild) were employed for the accelerated sliding-contact mouth-motion fatigue test. Twenty one crowns from each group were randomly distributed among these three profiles (1:2:4). Failure was designated as chip-off or bulk fracture. Optical and electron microscopes were used to examine the occlusal surface and subsurface damages, as well as the material microstructures. The resin composite crowns showed only minor occlusal damage during mouth-motion step-stress fatigue loading up to 1700N. Cross-sectional views revealed contact-induced cone cracks in all specimens, and flexural radial cracks in 2 crowns. Both cone and radial cracks were relatively small compared to the crown thickness. Extending these cracks to the threshold for catastrophic failure would require much higher indentation loads or more loading cycles. In contrast, all of the glass-ceramic crowns fractured, starting at loads of approximately 450N. Monolithic CAD/CAM resin composite crowns endure, with only superficial damage, fatigue loads 3-4 times higher than those causing catastrophic failure in glass-ceramic CAD crowns. Copyright © 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  7. Fatigue Resistance of CAD/CAM Resin Composite Molar Crowns

    Science.gov (United States)

    Shembish, Fatma A.; Tong, Hui; Kaizer, Marina; Janal, Malvin N.; Thompson, Van P.; Opdam, Niek J.; Zhang, Yu

    2016-01-01

    Objective To demonstrate the fatigue behavior of CAD/CAM resin composite molar crowns using a mouth-motion step-stress fatigue test. Monolithic leucite-reinforced glass-ceramic crowns were used as a reference. Methods Fully anatomically shaped monolithic resin composite molar crowns (Lava Ultimate, n = 24) and leucite reinforced glass-ceramic crowns (IPS Empress CAD, n = 24) were fabricated using CAD/CAM systems. Crowns were cemented on aged dentin-like resin composite tooth replicas (Filtek Z100) with resin-based cements (RelyX Ultimate for Lava Ultimate or Multilink Automix for IPS Empress). Three step-stress profiles (aggressive, moderate and mild) were employed for the accelerated sliding-contact mouth-motion fatigue test. Twenty one crowns from each group were randomly distributed among these three profiles (1:2:4). Failure was designated as chip-off or bulk fracture. Optical and electronic microscopes were used to examine the occlusal surface and subsurface damages, as well as the material microstructures. Results The resin composite crowns showed only minor occlusal damage during mouth-motion step-stress fatigue loading up to 1700 N. Cross-sectional views revealed contact-induced cone cracks in all specimens, and flexural radial cracks in 2 crowns. Both cone and radial cracks were relatively small compared to the crown thickness. Extending these cracks to the threshold for catastrophic failure would require much higher indentation loads or more loading cycles. In contrast, all of the glass-ceramic crowns fractured, starting at loads of approximately 450 N. Significance Monolithic CAD/CAM resin composite crowns endure, with only superficial damage, fatigue loads 3 – 4 times higher than those causing catastrophic failure in glass-ceramic CAD crowns. PMID:26777092

  8. Application of CAD/CAE/CAM in forging process: a review

    International Nuclear Information System (INIS)

    Ahmad Baharuddin Abdullah; Hamouda, A.M.S.

    2005-01-01

    Forging can be described as the process in which metal is plastically deformed with application of huge pressure. The process not only changes the shape but also improves the properties of the forged parts due to grain size refinement. Conventionally, the empirical trial and error method has been applied, but recently there are various tools are employed to improved product quality and economic of the process. For example, Computer Aided Design (CAD) is widely used in modeling of the process, while Computer Aided Engineering (CAE) tools have been utilized in analyzing the process. To physically demonstrate the process, Computer Aided Manufacturing (CAM) such as CNC machine has been exploited. In order to improve forging process efficiency, an integrated system that combines all advantages of CAD, CAM and CAE need to be developed. This paper presents an overview of computer aided simulation such as CAD, CAE and CAM application in forging process. (Author)

  9. Fabricating CAD/CAM Implant-Retained Mandibular Bar Overdentures: A Clinical and Technical Overview

    Directory of Open Access Journals (Sweden)

    Chui Ling Goo

    2017-01-01

    Full Text Available This report describes the clinical and technical aspects in the oral rehabilitation of an edentulous patient with knife-edge ridge at the mandibular anterior edentulous region, using implant-retained overdentures. The application of computer-aided design and computer-aided manufacturing (CAD/CAM in the fabrication of the overdenture framework simplifies the laboratory process of the implant prostheses. The Nobel Procera CAD/CAM System was utilised to produce a lightweight titanium overdenture bar with locator attachments. It is proposed that the digital workflow of CAD/CAM milled implant overdenture bar allows us to avoid numerous technical steps and possibility of casting errors involved in the conventional casting of such bars.

  10. Custom sectional impression trays with interlocking type handle for microstomia patients

    Directory of Open Access Journals (Sweden)

    Fernandes Aquaviva

    2009-01-01

    Full Text Available Making impressions in microstomia patients is often cumbersome. A modification of standard impression procedure is often necessary while treating such patients. This article describes the fabrication of a custom sectional impression tray with interlocking type of a handle for definitive impression procedures in a microstomia patient.

  11. The Utilisation of Shredded PET as Aggregate Replacement for Interlocking Concrete Block

    Science.gov (United States)

    Mokhtar, M.; Kaamin, M.; Sahat, S.; Hamid, N. B.

    2018-03-01

    The consumption of plastic has grown substantially all over the world in recent years and this has created huge quantities of plastic-based waste. Plastic waste is now a serious environmental threat to the modern way of living, although steps were taken to reduce its consumption. This creates substantial garbage every day, which is much unhealthy. Plastic bottles such as Polyethylene terephthalate (PET) was use as the partially component in this making of interlocking blocks concrete. This project investigates the strength and workability of the interlocking block concrete by replacing course aggregate with % PET. The suitability of recycled plastics (PET) as course aggregate in interlocking block concrete and its advantages are discussed here. Moreover, there were more benefits when using interlocking block than using conventional block such as it easy for construction because they are aligning, easy to place, high speed stacking and they offer more resistance to shear and buildings would be even stronger. Based on the test perform, the failure parameter were discussed .From the compressive strength test result, it shows that the strength of concrete block decreased with increased of PET used. From the results, it shows that higher compressive strength was found with 5% natural course aggregate replaced with PET compared to other percentages.

  12. A STUDY OF THE MANAGEMENT OF OPEN FRACTURES OF TIBIA BY UNREAMED INTERLOCKING NAIL

    OpenAIRE

    Harsha Kumar

    2015-01-01

    AIMS AND OBJECTIVES : 1. To evaluate the results of closed interlocking intramedullary nailing without reaming in the treatment of open fractures of the tibial shaft. (Gustillo type 1, type 2, type 3a, type 3b) . 2. To study the difficulties ( C omplications) encountered during the operative study. 3. To mobilize the patient early. ...

  13. Förster resonance energy transfer by formation of a mechanically interlocked [2]rotaxane

    NARCIS (Netherlands)

    Ogoshi, T.; Yamafuji, D.; Yamagishi, T.; Brouwer, A.M.

    2013-01-01

    A[2]rotaxane has been constructed from a di-pyrene appended pillar[5]arene wheel, a pyridinium axle, and a perylene stopper. It shows efficient Forster resonance energy transfer from pyrene to perylene by formation of a mechanically interlocked [2]rotaxane.

  14. 18 CFR 131.31 - FERC Form No. 561, Annual report of interlocking positions.

    Science.gov (United States)

    2010-04-01

    ... financial services or credit; mutual savings bank; or savings and loan association FINI Insurance company..., Annual report of interlocking positions. 131.31 Section 131.31 Conservation of Power and Water Resources... positions. (See section 46.4 of this chapter.) ER31DE98.003 INSTRUCTIONS FOR COMPLETING ANNUAL REPORT OF...

  15. Vertical interlocks of executives and performance of affiliated firms in state owned Chinese business groups

    DEFF Research Database (Denmark)

    Arnoldi, Jakob; Chen, Xin; Na, Chaohong

    increases. Our findings are consistent with the hypotheses that vertically interlocking executives can increase firm value by providing better protection against political interference and expropriation by the ultimate controllers of business groups. Our study sheds new light in the role and function...

  16. Internal Iliac Artery Embolization during an Endovascular Aneurysm Repair with Detachable Interlock Microcoils

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Woo ChuL; Jeon, Yong Sun; Hong, Kee Chun; Cho, Soon Gu; Park, Jae Young [Inha University Hospital, Inha University School of Medicine, Incheon (Korea, Republic of); Kim, Jang Yong [Dept. of Vascular and Endovascular Surgery, The Catholic University of Korea School of Medicine, Seoul (Korea, Republic of)

    2014-10-15

    The purpose of this study was to evaluate the effectiveness of detachable interlock microcoils for an embolization of the internal iliac artery during an endovascular aneurysm repair (EVAR). A retrospective review was conducted on 40 patients with aortic aneurysms, who had undergone an EVAR between January 2010 and March 2012. Among them, 16 patients were referred for embolization of the internal iliac artery for the prevention of type II endoleaks. Among 16 patients, 13 patients underwent embolization using detachable interlock microcoils during an EVAR. Computed tomographic angiographies and clinical examinations were performed during the follow-up period. Technical success, clinical outcome, and complications were reviewed. Internal iliac artery embolizations using detachable interlock microcoils were technically successful in all 13 patients, with no occurrence of procedure-related complications. Follow-up imaging was accomplished in the 13 cases. In all cases, type II endoleak was not observed with computed tomographic angiography during the median follow-up of 3 months (range, 1-27 months) and the median clinical follow-up of 12 months (range, 1-27 months). Two of 13 (15%) patients had symptoms of buttock pain, and one patient died due to underlying stomach cancer. No significant clinical symptoms such as bowel ischemia were observed. Internal iliac artery embolization during an EVAR using detachable interlock microcoils to prevent type II endoleaks appears safe and effective, although this should be further proven in a larger population.

  17. 28th International Conference on CAD/CAM, Robotics and Factories of the Future

    CERN Document Server

    Syan, Chanan

    2016-01-01

    This volume is based on the proceedings of the 28th International Conference on CAD/CAM, Robotics and Factories of the Future. This book specially focuses on the positive changes made in the field of robotics, CAD/CAM and future outlook for emerging manufacturing units. Some of the important topics discussed in the conference are product development and sustainability, modeling and simulation, automation, robotics and handling systems, supply chain management and logistics, advanced manufacturing processes, human aspects in engineering activities, emerging scenarios in engineering education and training. The contents of this set of proceedings will prove useful to both researchers and practitioners.

  18. CAD/CAM-assisted breast reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Melchels, Ferry; Hutmacher, Dietmar Werner [Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, QLD 4059 (Australia); Wiggenhauser, Paul Severin; Schantz, Jan-Thorsten [Department of Plastic and Hand Surgery, Klinikum rechts der Isar, Technische Universitaet Muenchen, Ismaninger Strasse 22, 81675 Munich (Germany); Warne, David; Barry, Mark [High Performance Computing and Research Support, Queensland University of Technology, Gardens Point Road, Brisbane, QLD 4000 (Australia); Ong, Fook Rhu; Chong, Woon Shin, E-mail: Dietmar.Hutmacher@qut.edu.au, E-mail: jtschantz@lrz.tu-muenchen.de [Singapore Polytechnic, 500 Dover Road, 139651 Singapore (Singapore)

    2011-09-15

    The application of computer-aided design and manufacturing (CAD/CAM) techniques in the clinic is growing slowly but steadily. The ability to build patient-specific models based on medical imaging data offers major potential. In this work we report on the feasibility of employing laser scanning with CAD/CAM techniques to aid in breast reconstruction. A patient was imaged with laser scanning, an economical and facile method for creating an accurate digital representation of the breasts and surrounding tissues. The obtained model was used to fabricate a customized mould that was employed as an intra-operative aid for the surgeon performing autologous tissue reconstruction of the breast removed due to cancer. Furthermore, a solid breast model was derived from the imaged data and digitally processed for the fabrication of customized scaffolds for breast tissue engineering. To this end, a novel generic algorithm for creating porosity within a solid model was developed, using a finite element model as intermediate.

  19. Radiometric Calibration for AgCam

    Directory of Open Access Journals (Sweden)

    Edward Hildum

    2010-02-01

    Full Text Available The student-built Agricultural Camera (AgCam now onboard the International Space Station observes the Earth surface through two linescan cameras with Charge-Coupled Device (CCD arrays sensitive to visible and near-infrared wavelengths, respectively. The electro-optical components of the AgCam were characterized using precision calibration equipment; a method for modeling and applying these measurements was derived. Correction coefficients to minimize effects of optical vignetting, CCD non-uniform quantum efficiency, and CCD dark current are separately determined using a least squares fit approach. Application of correction coefficients yields significant variability reduction in flat-field images; comparable results are obtained when applied to ground test images.

  20. CAD/CAM-assisted breast reconstruction

    International Nuclear Information System (INIS)

    Melchels, Ferry; Hutmacher, Dietmar Werner; Wiggenhauser, Paul Severin; Schantz, Jan-Thorsten; Warne, David; Barry, Mark; Ong, Fook Rhu; Chong, Woon Shin

    2011-01-01

    The application of computer-aided design and manufacturing (CAD/CAM) techniques in the clinic is growing slowly but steadily. The ability to build patient-specific models based on medical imaging data offers major potential. In this work we report on the feasibility of employing laser scanning with CAD/CAM techniques to aid in breast reconstruction. A patient was imaged with laser scanning, an economical and facile method for creating an accurate digital representation of the breasts and surrounding tissues. The obtained model was used to fabricate a customized mould that was employed as an intra-operative aid for the surgeon performing autologous tissue reconstruction of the breast removed due to cancer. Furthermore, a solid breast model was derived from the imaged data and digitally processed for the fabrication of customized scaffolds for breast tissue engineering. To this end, a novel generic algorithm for creating porosity within a solid model was developed, using a finite element model as intermediate.

  1. Hands-on robotic distal interlocking in intramedullary nail fixation of femoral shaft fractures.

    Science.gov (United States)

    Oszwald, Markus; Westphal, Ralf; Stier, Rebecca; Gaulke, Ralph; Calafi, Afshin; Müller, Christian W; Wahl, Friedrich; Krettek, Christian; Gösling, Thomas

    2010-01-01

    Intramedullary nailing has become the gold standard in the treatment of femoral shaft fractures. This procedure involves the placement of distal interlocking bolts using the freehand technique. Accurate placement of distal interlocks can be a challenging task, especially in inexperienced hands. Misplacement of distal interlocking bolts can lead to iatrogenic fracture, instability of the bone-implant construct, or even malalignment of the extremity. Repeated drilling attempts increase radiation exposure and can cause additional bony and soft tissue trauma. We hypothesize that robot-guided placement of distal interlocks is more accurate, precise, and efficient than the freehand technique. A custom-designed drill guide was mounted onto the arm of an industrial robot. We developed a special device to secure a generic block (Synbone, Malans, Switzerland) into which an intramedullary nail could be inserted in a standardized way. A metric scale allowed later measurements of the drillings. Digital images were taken from each side of the block for analysis of the drilling trajectories. The fluoroscope was adjusted to obtain perfect circles of the distal interlocking holes. The number of images necessary to achieve this was recorded. The axis was recognized automatically by using the differences in contrast between the matrix of the generic bone and the implant (intramedullary nail). The drill trajectories were then computed. The robot with the mounted drill-guide automatically moved onto the calculated trajectory. The surgeon then executed the drilling. We performed 40 robot assisted drillings in generic blocks. Freehand drilling served as our control group. Analysis of the digital images revealed a mean deviation of 0.94 mm and 2.7° off the ideal trajectory using robotic assistance. In 100% of the cases (n = 40), the distal locking hole was hit. A mean of 8.8 images was acquired. After manual drilling, 92.5% of the distal interlocks were hit. A mean deviation of 3.66 mm

  2. Cam Gears Dynamics in the Classic Distribution

    Directory of Open Access Journals (Sweden)

    Florian Ion Petrescu

    2014-01-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 The paper presents an original method to determine the general dynamics of mechanisms with rotation cams and followers, particularized to the plate translated follower. First, one presents the dynamics kinematics. Then one solves the Lagrange equation and with an original dynamic model with one degree of freedom, with variable internal amortization, it makes the dynamic analysis of two models.

  3. CAM and Cell Fate Targeting: Molecular and Energetic Insights into Cell Growth and Differentiation

    Directory of Open Access Journals (Sweden)

    Carlo Ventura

    2005-01-01

    Full Text Available Evidence-based medicine is switching from the analysis of single diseases at a time toward an integrated assessment of a diseased person. Complementary and alternative medicine (CAM offers multiple holistic approaches, including osteopathy, homeopathy, chiropractic, acupuncture, herbal and energy medicine and meditation, all potentially impacting on major human diseases. It is now becoming evident that acupuncture can modify the expression of different endorphin genes and the expression of genes encoding for crucial transcription factors in cellular homeostasis. Extremely low frequency magnetic fields have been found to prime the commitment to a myocardial lineage in mouse embryonic stem cells, suggesting that magnetic energy may direct stem cell differentiation into specific cellular phenotypes without the aid of gene transfer technologies. This finding may pave the way to novel approaches in tissue engineering and regeneration. Different ginseng extracts have been shown to modulate growth and differentiation in pluripotent cells and to exert wound-healing and antitumor effects through opposing activities on the vascular system, prompting the hypothesis that ancient compounds may be the target for new logics in cell therapy. These observations and the subtle entanglement among different CAM systems suggest that CAM modalities may deeply affect both the signaling and transcriptional level of cellular homeostasis. Such a perception holds promises for a new era in CAM, prompting reproducible documentation of biological responses to CAM-related strategies and compounds. To this end, functional genomics and proteomics and the comprehension of the cell signaling networks may substantially contribute to the development of a molecular evidence–based CAM.

  4. CAMS as a tool for identifying and predicting abnormal plant states using real-time simulation

    International Nuclear Information System (INIS)

    Fantoni, P.F.; Soerenssen, A.; Meyer, G.

    1999-01-01

    CAMS (Computerised Accident Management Support) is a system that provides assistance to the staff in a nuclear power plant control room, in the technical support centre and in the national safety centre. Support is offered in identification of the current plant state, in assessment of the future development of the accident and in planning mitigation strategies. CAMS is a modular system, where several modules perform different tasks under the control and supervision of a central knowledge based system, which is responsible of the syncronisation and the flow of information through the activated modules. A CAMS prototype has been tested by the Swedish Nuclear Inspectorate during a safety exercise in Sweden in 1995, with satisfactory results. Future developments include automatic control of the Predictive Simulator by the State Identification, for the generation of possible mitigation strategies, and the development of an improved user interface which considers the integration of the system in an advanced control room. CAMS is a system developed as a joint research activity at the Halden Reactor Project in close cooperation with member organisations. The project, started in 1993, has now arrived to the second prototype version, which has been presented and demonstrated at several seminars and workshops around the world. (author)

  5. CAD/CAM technology for implant abutments, crowns, and superstructures.

    Science.gov (United States)

    Kapos, Theodoros; Evans, Christopher

    2014-01-01

    The aim of this systematic review was to compare implant prostheses fabricated by computer-assisted design and computer-assisted manufacturing (CAD/CAM) with conventionally fabricated implant prostheses when assessing esthetics, complications (biologic and mechanical), patient satisfaction, and economic factors. Electronic searches for clinical studies focusing on long-term follow-up were performed using the PubMed and Ovid search engines. Concentrating on the restorative aspect of the CAD/CAM technology applicable to implant dentistry, pertinent literature was divided into articles related to implant abutments, crowns, and frameworks. A total of 18 articles satisfied the inclusion criteria. Two articles reported on CAD/CAM crowns, six on abutments, and 10 on implant-supported CAD/CAM frameworks. The mean survival rate for CAD/CAM crowns was 98.85% and for CAD/CAM abutments 100%. The mean survival rate for CAD/CAM frameworks was 95.98%. Based on the current literature, CAD/CAM fabricated crowns, abutments, and frameworks demonstrate survival rates comparable to conventionally fabricated prostheses. Implant survival appears unaffected by fabrication technique. Since this technology encompasses several manufacturing variations, a new definition might be necessary to accurately define the processes under which the CAD/CAM restorations are fabricated. "Complete CAD/CAM product" where no or minimal manual intervention is employed could be a possible term.

  6. Achievement report for fiscal 1998 on Simple Operation Type CAD/CAM System Development through International Cooperation; 1998 nendo 'kan'i sosagata denshi sekkei seian shien system no kaihatsu ni kansru kenkyu kyoryoku' ni kansuru hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The subject project is implemented in the fields of automobiles and their parts, electrical home appliances and their parts, and textile and apparel. In the field of automobiles and their parts, a prototype is developed of an integrated information management system which is to serve between corporation head offices and assembling businesses overseas, and another prototype is developed of an inter-business technical data serving system which is to serve between overseas assembling businesses and supporting businesses, both involving Japan, Indonesia, and Thailand. In the field of electrical home appliances and their parts, a prototype is developed of an electronic catalog system in a joint endeavor with research institutes of Indonesia, Malaysia, Singapore, and Thailand, and a demonstration test is conducted. A design concurrent engineering system is developed by Japan and Malaysian research institutes. In the field of textile and apparel, prototypes are developed, by Japanese, Chinese, and Indonesian apparel manufactures, of an apparel manufacturing specification system, international EDI (electronic data interchange) system, translation system, and a CAD (computer-aided design)/CAM (computer-aided manufacturing) data interchange system. (NEDO)

  7. Single crowns with CAD/CAM-fabricated copings from titanium: 6-year clinical results.

    Science.gov (United States)

    Hey, Jeremias; Beuer, Florian; Bensel, Tobias; Boeckler, Arne F

    2014-08-01

    Computer-aided design/computer-aided manufacturing (CAD/CAM) titanium ceramic restorations were developed with the potential for replacing expensive, high noble metal ceramic restorations. However, little information exists about the clinical performance of CAD/CAM titanium ceramic single crowns. The purpose of this study was to evaluate CAD/CAM titanium ceramic single crowns after 6 years in function. A total of 41 crowns were fabricated for 21 patients. The titanium copings were CAD/CAM milled (Everest CAD/CAM system), with an even thickness of 0.5 mm and veneered with low-fusing porcelain (Vita Titanium Porcelain) in the powder-build-up technique. All the crowns were cemented with zinc phosphate. The participants were recalled at 12, 24, 36, 48, 60, and 72 months after cementation to document any mechanical and biologic complications and to measure the periodontal parameters, such as probing depth, bleeding on probing, and the plaque index. The success and survival rates were calculated according to the Kaplan-Meier analysis. After 6 years of clinical service, 12 mechanical complications and 1 biologic complication were found, which resulted in a success rate of 67.8%. The cumulative survival rate of the crowns was 91.3% after 6 years. At the end of the follow-up period, the probing depth was 3.21 mm, the percentile of surface with bleeding on probing was 25, and the plaque index was 0.37. No secondary caries or decementation was detected during the 6-year observation period. The clinical performance of the CAD/CAM titanium-ceramic crowns after 6 years was poor because of veneering porcelain problems. Recent CAD software with tools to design proper copings might improve the clinical success. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  8. Treatment Preferences for CAM in Children with Chronic Pain

    OpenAIRE

    Tsao, Jennie C. I.; Meldrum, Marcia; Kim, Su C.; Jacob, Margaret C.; Zeltzer, Lonnie K.

    2006-01-01

    CAM therapies have become increasingly popular in pediatric populations. Yet, little is known about children's preferences for CAM. This study examined treatment preferences in chronic pediatric pain patients offered a choice of CAM therapies for their pain. Participants were 129 children (94 girls) (mean age = 14.5 years ± 2.4; range = 8–18 years) presenting at a multidisciplinary, tertiary clinic specializing in pediatric chronic pain. Bivariate and multivariate analyses were used to examin...

  9. Post-cam mechanics and tibiofemoral kinematics: a dynamic in vitro analysis of eight posterior-stabilized total knee designs.

    Science.gov (United States)

    Arnout, N; Vanlommel, L; Vanlommel, J; Luyckx, J P; Labey, L; Innocenti, B; Victor, J; Bellemans, J

    2015-11-01

    Posterior cruciate ligament (PCL)-substituting total knee arthroplasty (TKA) designs were introduced to avoid paradoxical roll forward of the femur and to optimize knee kinematics. The aim of this in vitro study was to investigate post-cam function and contact mechanics and relate it to knee kinematics during squatting in eight contemporary posterior-stabilized TKA designs. All prostheses were fixed on custom-designed metal fixtures and mounted in a knee rig and five sequential-loaded squats were performed between 30° and 130° of flexion. Contact pressure and contact area were measured using pressure-sensitive Tekscan sensors on the posterior face of the post. Kinematics was recorded with reflective markers and infrared light-capturing cameras. The post-cam mechanisms analyzed in this study are very variable in terms of design features. This leads to large variations in terms of the flexion angle at which the post and cam engage maximal contact force, contact pressure and contact area. We found that more functional post-cam mechanisms, which engage at lower flexion angle and have a similar behavior as normal PCL function, generally show more normal rollback and tibial rotation at the expense of higher contact forces and pressures. All designs show high contact forces. A positive correlation was found between contact force and initial contact angle. Post-cam contact mechanics and kinematics were documented in a standardized setting. Post-cam contact mechanics are correlated with post-cam function. Outcomes of this study can help to develop more functional designs in future. Nevertheless, a compromise will always be made between functional requirements and risk of failure. We assume that more normal knee kinematics leads to more patient satisfaction because of better mobility. Understanding of the post-cam mechanism, and knowing how this system really works, is maybe the clue in further development of new total knee designs.

  10. Colour stainability of indirect CAD-CAM processed composites vs. conventionally laboratory processed composites after immersion in staining solutions.

    Science.gov (United States)

    Arocha, Mariana A; Basilio, Juan; Llopis, Jaume; Di Bella, Enrico; Roig, Miguel; Ardu, Stefano; Mayoral, Juan R

    2014-07-01

    The aim of this study was to determine, by using a spectrophotometer device, the colour stainability of two indirect CAD/CAM processed composites in comparison with two conventionally laboratory-processed composites after being immersed 4 weeks in staining solutions such as coffee, black tea and red wine, using distilled water as control group. Two indirect CAD/CAM composites (Lava Ultimate and Paradigm MZ100) and two conventionally laboratory-processed composites (SR Adoro and Premise Indirect) of shade A2 were selected (160 disc samples). Colour stainability was measured after 4 weeks of immersion in three staining solutions (black tea, coffee, red wine) and distilled water. Specimen's colour was measured each week by means of a spectrophotometer (CIE L*a*b* system). Statistical analysis was carried out performing repeated ANOVA measurements and Tukey's HSD test to evaluate differences in ΔE00 measurements between groups; the interactions among composites, staining solutions and time duration were also evaluated. All materials showed significant discoloration (pcolour stability compared with CAD/CAM resin blocks. CAD/CAM processed composites immersed in staining solutions showed lower colour stability when compared to conventionally laboratory-processed resin composites. The demand for CAD/CAM restorations has been increasing; however, colour stainability for such material has been insufficiently studied. Moreover, this has not been performed comparing CAD/CAM processed composites versus laboratory-processed indirect composites by immersing in staining solutions for long immersion periods. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. The influence of polishing techniques on pre-polymerized CAD\\CAM acrylic resin denture bases.

    Science.gov (United States)

    Alammari, Manal Rahma

    2017-10-01

    Lately, computer-aided design and computer-aided manufacturing (CAD/CAM) has broadly been successfully employed in dentistry. The CAD/CAM systems have recently become commercially available for fabrication of complete dentures, and are considered as an alternative technique to conventionally processed acrylic resin bases. However, they have not yet been fully investigated. The purpose of this study was to inspect the effects of mechanical polishing and chemical polishing on the surface roughness (Ra) and contact angle (wettability) of heat-cured, auto-cured and CAD/CAM denture base acrylic resins. This study was conducted at the Advanced Dental Research Laboratory Center of King Abdulaziz University from March to June 2017. Three denture base materials were selected: heat cure poly-methylmethacrylate resin, thermoplastic (polyamide resin) and (CAD\\CAM) denture base resin. Sixty specimens were prepared and divided into three groups, twenty in each. Each group was divided according to the polishing techniques into (Mech P) and (Chem P), ten specimens in each; surface roughness and wettability were investigated. Data were analyzed by SPSS version 22, using one-way ANOVA and Pearson coefficient. One-way analysis of variance (ANOVA) and post hoc tests were used for comparing the surface roughness values between three groups which revealed a statistical significant difference between them (p 1 CAD\\CAM denture base material (group III) showed the least mean values (1.08±0.23, 1.39±0.31, Mech P and Chem P respectively). CAD/CAM showed the least contact angle in both polishing methods, which were statistically significant at 5% level (p=0.034 and pCAD\\CAM denture base resin with superior smooth surface compared to chemical polishing. Mechanical polishing is considered the best effective polishing technique. CAD/CAM denture base material should be considered as the material of choice for complete denture construction in the near future, especially for older dental

  12. Marginal accuracy of titanium copings fabricated by casting and CAD/CAM techniques.

    Science.gov (United States)

    Witkowski, Siegbert; Komine, Futoshi; Gerds, Thomas

    2006-07-01

    Advances in computer-aided design/computer-assisted manufacturing (CAD/CAM) technology purportedly enhance the marginal fit of dental restorations. However, little information is available on the marginal accuracy of restorations manufactured with various CAD/CAM systems. The purpose of this study was to evaluate and compare the marginal accuracy and refinement time of titanium copings fabricated by 3 different CAD/CAM systems relative to standard casting techniques. Sixty-four stone die duplicates of a human maxillary central incisor, prepared for a metal-ceramic crown, with a uniform chamfer design, were divided into 4 groups (n=16). The specimens were restored with titanium copings using CAD/CAM systems Pro 50 (PRO), DCS (DCS), and Everest (EVE). A conventional titanium casting technique, Biotan (BIO), served as a control. Vertical and horizontal discrepancies between restoration margins and the preparations were each measured before and after manual refinement. This refinement was completed using a disclosing agent and by removing the internal positive defects of the copings. The marginal discrepancies of the copings were evaluated at 4 standard areas using 10 measurements, for a total of 160 measurements of each margin. Repeated-measures ANOVA was used for analyzing marginal accuracy. The coping refinement time was analyzed with the Kruskal-Wallis and post hoc Wilcoxon rank sum tests (alpha=.05). The marginal discrepancies (microm) ranged from 32.9 to 127.8 before and from 3.4 to 58.4 after the manual refinement of copings. Manual refinement significantly improved the marginal accuracy (P4.0 for EVE, and 4.0 for BIO (Kruskal-Wallis-test: P<.0001). Manual adjustment significantly improves the marginal accuracy of CAD/CAM system-fabricated titanium copings. The highest marginal accuracy was achieved with the DCS system, using a longer refinement time.

  13. Neurobiology of Acupuncture: Toward CAM

    Directory of Open Access Journals (Sweden)

    Sheng-Xing Ma

    2004-01-01

    Full Text Available It has long been accepted that acupuncture, puncturing and scraping needles at certain points on the body, can have analgesic and anesthetic effects, as well as therapeutic effects in the treatment of various diseases. This therapy, including acupuncture anesthesia, has drawn the attention of many investigators and become a research subject of international interest around the world. Numerous studies have demonstrated that the nervous system, neurotransmitters, endogenous substances and Jingluo (meridians may respond to needling stimulation and electrical acupuncture. An abundance of information has now accumulated concerning the neurobiological mechanisms of acupuncture, in relation to both neural pathways and neurotransmitters/hormonal factors that mediate autonomic regulation, pain relief and other therapeutics. Early studies demonstrated that the analgesic effects of electroacupuncture (EA are mediated by opioid peptides in the periaqueductal gray. Recent evidence shows that nitric oxide plays an important role in mediating the cardiovascular responses to EA stimulation through the gracile nucleus-thalamic pathway. Other substances, including serotonin, catecholamines, inorganic chemicals and amino acids such as glutamate and α-aminobutyric acid (GABA, are proposed to mediate certain cardiovascular and analgesic effects of acupuncture, but at present their role is poorly understood. The increased interest in acupuncture health care has led to an ever-growing number of investigators pursuing research in the processes of the sense of needling touch, transduction of needling stimulation signals, stimulation parameters and placebos. In this Review, the evidence and understanding of the neurobiological processes of acupuncture research have been summarized with an emphasis on recent developments of nitric oxide mediating acupuncture signals through the dorsal medulla-thalamic pathways.

  14. New Content Addressable Memory (CAM) Technologies for Big Data and Intelligent Electronics Enabled by Magneto-Electric Ternary CAM

    Science.gov (United States)

    2017-12-11

    higher frequency than its intrinsic search delay. Furthermore, the MeTCAM incorporates the state-of-the art nonvolatile memory device, the voltage...faster speed compared to the software lookup. There are two types of CAM: binary CAM and ternary CAM (TCAM). Especially, TCAM has not only two binary...scalability. These characteristics allow MTJs interacting with the-state-of-the- art charge- based electronics on the same chip as a non-volatile

  15. Expression, crystallization and preliminary diffraction studies of the Pseudomonas putida cytochrome P450cam operon repressor CamR

    International Nuclear Information System (INIS)

    Maenaka, Katsumi; Fukushi, Kouji; Aramaki, Hironori; Shirakihara, Yasuo

    2005-01-01

    The P. putida cytochrome P450cam operon repressor CamR has been expressed in E. coli and crystallized in space group P2 1 2 1 2. The Pseudomonas putida cam repressor (CamR) is a homodimeric protein that binds to the camO DNA operator to inhibit the transcription of the cytochrome P450cam operon camDCAB. CamR has two functional domains: a regulatory domain and a DNA-binding domain. The binding of the inducer d-camphor to the regulatory domain renders the DNA-binding domain unable to bind camO. Native CamR and its selenomethionyl derivative have been overproduced in Escherichia coli and purified. Native CamR was crystallized under the following conditions: (i) 12–14% PEG 4000, 50 mM Na PIPES, 0.1 M KCl, 1% glycerol pH 7.3 at 288 K with and without camphor and (ii) 1.6 M P i , 50 mM Na PIPES, 2 mM camphor pH 6.7 at 278 K. The selenomethionyl derivative CamR did not crystallize under either of these conditions, but did crystallize using 12.5% PEG MME 550, 25 mM Na PIPES, 2.5 mM MgCl 2 pH 7.3 at 298 K. Preliminary X-ray diffraction studies revealed the space group to be orthorhombic (P2 1 2 1 2), with unit-cell parameters a = 48.0, b = 73.3, c = 105.7 Å. Native and selenomethionyl derivative data sets were collected to 3 Å resolution at SPring-8 and the Photon Factory

  16. *Abstracts - 7th IN-CAM Research Symposium, Evaluating CAM Practices: Effectiveness, Integration, Economics & Safety - November 2012.

    Science.gov (United States)

    Boon, Heather; Verhoef, Marja J

    2012-10-23

    Abstract The following are abstracts of oral and poster presentations given at the 7th IN-CAM Research Symposium - Evaluating CAM Practices: Effectiveness, Integration, Economics & Safety, and the 4th HomeoNet Research Forum, a pre-Symposium event. The IN-CAM Research Symposium was held November 2 to 4, 2012 at the Leslie Dan Faculty of Pharmacy, University of Toronto, in Toronto, Ontario, Canada. For more information, please visit: www.incamresearch.ca.

  17. Optical integration of CAD/CAM materials.

    Science.gov (United States)

    Güth, Jan-Frederik; Magne, Pascal

    The optical integration (OI) of monolithic CAD/CAM materials under 4 illuminations was evaluated using a standardized and clinically relevant method. Eighteen inlays were manufactured and placed (glycerin gel). Standardized photos were taken under 4 illuminations (neutral white light direct and indirect illumination, cross-polarized light, fluorescent light). Six evaluators defined the optical integration score (OIS) as the "visibility" of the restoration (0 = worst OI, 4 = optimal OI). The intact tooth served as control. The null hypothesis was that different illuminations did not influence the OI of CAD/CAM inlays. One-way ANOVA, followed by Scheffe's post hoc, was applied (P = 0.05). Neutral light direct illumination: OIS between 2.67 (IPS e.max CAD LT A1, ENAMIC A1) and 3.83 (IPS e.max CAD HT A1) with a mean of 3.28 (± 0.339). Indirect illumination: OIS from 1.00 (Paradigm MZ100 A1) to 2.41 (ENAMIC A1) with a mean of 1.88 (± 0.598). Fluorescent light: OIS between 0.75 and 3.25 with a mean of 1.67 (± 1.025). ENAMIC and VITA BLOCS Mark II showed the best optical integration in fluorescence. IPS e.max CAD, Paradigm MZ 100 demonstrated low fluorescence; Lava Ultimate high fluorescence. OI was influenced by different illumination. A simple method accessible to clinicians for additional evaluation of CAD/CAM materials in daily practice is presented. All materials showed excellent OI under direct illumination with neutral white light. The most pronounced differences in optical integration between tooth and evaluated materials were observed under fluorescent light.

  18. CLIC main beam quadrupole active pre-alignment based on cam movers

    CERN Document Server

    Kemppinen, J; Leuxe, R; Mainaud Durand, H; Sandomierski, J; Sosin, M

    2012-01-01

    Compact Linear Collider (CLIC) is a study for a future 48 km long linear electron-positron collider in the multi TeV range. Its target luminosity can only be reached if the main beam quadrupoles (MB quads) are actively pre-aligned within 17 µm in sliding windows of 200 m with respect to a straight reference line. In addition to the positioning requirement, the pre-alignment system has to provide a rigid support for the nano-stabilization system to ensure that the first eigenfrequency is above 100 Hz. Re-adjustment based on cam movers was chosen for detailed studies to meet the stringent pre-alignment requirements. There are four different types of MB quads in CLIC. Their lengths and masses vary so that at least two types of cam movers have to be developed. The validation of the cams with less stringent space restrictions has proceeded to a test setup in 5 degrees of freedom (DOF). Prototypes of the more demanding, smaller cams have been manufactured and they are under tests in 1 DOF. This paper describes the...

  19. The Effects of Interlocking a Universal Hip Cementless Stem on Implant Subsidence and Mechanical Properties of Cadaveric Canine Femora.

    Science.gov (United States)

    Buks, Yonathan; Wendelburg, Kirk L; Stover, Susan M; Garcia-Nolen, Tanya C

    2016-02-01

    To determine if an interlocking bolt would limit subsidence of the biological fixation universal hip (BFX(®)) femoral stem under cyclic loading and enhance construct stiffness, yield, and failure properties. Ex vivo biomechanical study. Cadaveric canine femora (10 pairs). Paired femora implanted with a traditional stem or an interlocking stem (constructs) were cyclically loaded at walk, trot, and gallop loads while implant and bone motions were captured using kinematic markers and high-speed video. Constructs were then loaded to failure to evaluate failure mechanical properties. Implant subsidence was greater (P = .037) for the traditional implant (4.19 mm) than the interlocking implant (0.78 mm) only after gallop cyclic loading, and cumulatively after walk, trot, and gallop cyclic loads (5.20 mm vs. 1.28 mm, P = .038). Yield and failure loads were greater (P = .029 and .002, respectively) for the interlocking stem construct (1155 N and 2337 N) than the traditional stem construct (816 N and 1405 N). Version angle change after cyclic loading was greater (P = .020) for the traditional implant (3.89 degrees) than for the interlocking implant (0.16 degrees), whereas stem varus displacement at failure was greater (P = .008) for the interlocking implant (1.5 degrees) than the traditional implant (0.17 degrees). Addition of a stabilizing bolt enhanced construct stability and limited subsidence of a BFX(®) femoral stem. Use of the interlocking implant may decrease postoperative subsidence. However, in vivo effects of the interlocking bolt on osseointegration, bone remodeling, and stress shielding are unknown. © Copyright 2016 by The American College of Veterinary Surgeons.

  20. Uptake and photodynamic activity of porphycenes in tumor cells implanted on the chick chorioallantoic membrane (CAM)

    Science.gov (United States)

    Davidi, Ronit; Gottfried, Varda; Kimel, Sol

    1996-01-01

    The chick chorioallantoic membrane (CAM) is a convenient model for the study of photodynamic therapy (PDT). This membrane has a rich vasculature, which mimics the tumor neovasculature, and can also serve as a host for implanted tumors. The transparency of the CAM enables in-vivo monitoring of vascular changes during and post PDT, without the need to sacrifice test animals at each time point. Video documentation and analysis of events occurring during and after irradiation permit the quantification of changes in vessel morphology, blood perfusion and tumor development. The compounds tested in this study belong to a family of potential sensitizers -- the porphycenes. These are phorphyrin isomers based on a 16-membered macrocycle, in which the four methine moieties linking the pyrrole rings have been replaced by two direct bonds and two ethine bridges. Experiments were performed on blood vessels of the intact CAM and on recurrent human melanoma cells implanted on the CAM. Tumor selectivity was demonstrated by measuring drug uptake using fluorescence methods. A sensitizer injected systemically into the embryo yolk sac could be detected in the blood vessels 30 min after injection; 1 h later the sensitizer had preferentially accumulated in the tumor. Tumors were irradiated at the optimal uptake time (after 1 h) for 16 min with a 20 mW HeNe laser. Video image analysis showed that 96 h after irradiation tumors had decreased to 5% of their original size. In contrast, non-irradiated control tumors on the same CAM, continued to proliferate and grew to more than twice their original size. In addition, we observed a difference in the damage mechanism after systemic compared to topical administration. Topical application followed by irradiation caused fast necrosis of tumors, which might suggest direct damage to tumor cells, whereas after systemic administration, PDT damage was manifested by slower necrosis, presumably caused by vascular destruction.

  1. A CLINICAL STUDY OF SURGICAL MANAGEMENT OF DIAPHYSEAL FRACTURES OF TIBIA WITH INTRAMEDULLARY INTERLOCKING NAIL

    OpenAIRE

    Radhakrishna; Shivananda; Santhosh Kumar

    2014-01-01

    BACKGROUND: Intramedullary interlocking is currently considered the treatment of choice for tibial shaft fractures, with high rates of fracture union, advantage of early stabilization which decreases the morbidity and mortality rate in patients, allows early mobilization, reduces the incidence of infection, malunion, non-union or implant failure. OBJECTIVES: To assess and study diaphyseal fractures of tibia and to evaluate the functional outcome of patients with tibial shaft fracture treated ...

  2. [Proximal interlocking of humeral intramedullary nails and risk of axillary nerve injury].

    Science.gov (United States)

    Blum, J; Rommens, P M

    2002-01-01

    Possible injuries to the axillary nerve are criticised in antegrade and retrograde endomedullary nailing of the humeral shaft during proximal interlocking. Clinical experience seems not to support the theory of a high risk of nerve injury. The real risk although remains unknown under anatomical-morphological aspects. Eight complete human cadaveric shoulder-arm regions with original soft-tissue coverage had been used. Four times the unreamed humeral nail (UHN) had been inserted retrograde, and four times antegrade, distributed in each pair. Antegrade interlocking was performed after skin incision and spreading of soft tissues through the aiming devices. This involved one oblique bolt from lateral to medial. Retrograde proximal interlocking was performed under image intensifier. This involved triple interlocking, once dorso-ventrally and twice latero-medially. The incision paths have been marked. After preparation of the nerve stem in the lateral axillary portal the different branches have been searched and exposed. The spatial relations of bolts and nerve branches have been measured and the insertion path of the bolts has been revised, finally lesions of nerve structures have been documented. We found the latero-medially inserted bolt heads of the retrograde approach and the oblique bolt head of the antegrade approach being placed in a safe distance from the medio-dorsally positioned stem of the axillary nerve. On the other hand the dorsoventrally inserted bolt head (retrograde approach) showed in most cases a very tight relation to the nerve stem. Exploring the axillary nerve and its branches showed in no case a direct nerve lesion. We suggest to perform only a sharp cutaneous incision and then to prepare the muscle only by careful spreading until touching bone, with tissue retraction during drilling. In retrograde nailing the dorso-ventral bolt should only be used in extreme proximal fractures.

  3. Development of an interlocked nail for segmental defects in the rabbit tibia.

    Science.gov (United States)

    LeCronier, David J; Papakonstantinou, John S; Gheevarughese, Vineetha; Beran, Casey D; Walter, Norman E; Atkinson, Patrick J

    2012-04-01

    Previous animal models have been developed to study intramedullary nailing for challenging segmental defects in the tibia. In large animals, interlocked nail fixation created a stable environment suitable to study new bone growth technologies placed in the defect. To our knowledge, there are no comparable interlocked tibial defect models for the rabbit in which new technologies could be evaluated. Such a model would be helpful since the rabbit is a popular initial model for orthopedic research studies owing to its wide availability and low cost. While numerous studies have nailed the rabbit tibia, all were non-locked implants that allowed some degree of instability between the fracture fragments. In addition, the non-locked nails were constructed of stainless steel, whereas human nails are increasingly made from titanium alloy. In the current study, an interlocked titanium nail was developed for the rabbit tibia. It was implanted in cadaver tibiae and subjected to fatigue cycling in combined compression and bending at physiologic levels to 21,061 cycles. This duration is estimated to represent 12 weeks of gait by the animal. Before and after fatigue cycling, monotonic testing was performed in compression and bending at physiologic levels. The intact contralateral limbs served as controls. All limbs completed the cycling; the instrumented limbs exhibited interfragmentary cyclic strain amplitudes during fatigue (616 +/- 139 micro-strain), which was significantly greater than the control limbs (136 +/- 35 microstrain). Monotonic strain amplitudes for the test limbs in bending and compression were 4839 +/- 1028 and 542 +/- 122 microstrain, respectively; corresponding values for the control bones were 407 +/- 118 and 95 +/- 38 microstrain, respectively. These data are similar to those presented in prior studies in larger bone models. The current study presents one method for interlocked nail fixation for this complex tibial shaft fracture in a small animal.

  4. Radiation-free Insertion of Distal Interlocking Screw in Tibial and Femur Nailing: A Simple Technique.

    Science.gov (United States)

    Soni, Ritesh Kumar; Mehta, Surender Mohan; Awasthi, Bhanu; Singh, Janith Lal; Kumar, Amit; Thakur, Lokesh; Tripathy, Sujit Kumar

    2012-01-01

    Distal interlocking screw insertion in intramedullary nailing of long-bone fracture is a challenging task for orthopedic surgeons. It is difficult particularly when the surgeon is in his learning stage or when image intensifier is not available. We describe a radiation-free technique of distal interlocking screw insertion which is easy and practicable. In this technique, a same length nail is placed over the skin (outer nail) and through its distal-most screw hole, a 3.2 mm drill bit is inserted to drill the distal locking screw hole of the intramedullary nail (inner nail). With a small skin incision over the distal screw holes, the distal-most screw hole is identified; the bone window overlying the screw hole is widened with an awl and a locking bolt is inserted with a washer under direct visualization. The other distal interlocking screw is simply drilled by matching the other three holes of the outer and inner nails. We have operated 86 patients (39 femoral shaft fracture and 47 tibial shaft fracture) in 1 year where this technique was used. There were 41 open fracture and 45 closed fracture. Within 6 months of follow-up, bony union was achieved in 36 of 39 femur fractures and 45 of 47 tibial fractures. No unwanted complications were observed during the postoperative period and in follow-up. This method of radiation-free distal interlocking screw insertion is simple and can be used in third world country where image intensifier facility is not available. However, surgeons are encouraged to use image intensifier facility where the facility is available.

  5. A STUDY OF THE MANAGEMENT OF OPEN FRACTURES OF TIBIA BY UNREAMED INTERLOCKING NAIL

    Directory of Open Access Journals (Sweden)

    Kuppa Srinivas

    2015-01-01

    Full Text Available AIMS AND OBJECTIVES: To evaluate the results of closed interlocking intramedullary nailing without reaming in the treatment of open fractures of t he tibial shaft and study the difficulties (complications encountered during the operative study. To compare the efficacy of interlocking intramedullary nailing without reaming in treating open fractures of tibia, Time required for the union of fracture, Range of motion of ankle and knee joint, Rate of malunion and mal rotation and Pain at the knee joint. RESULTS: The average age of patient is 32 years,83.33% are males, road traffic accidents account for majority(79.16%,right side involved in 58.33%,gustillo type II and type I compound fractures are common, full range of movements is seen in 66.67% by 12 weeks and union occurred in 95.83% by 9 months. Thirteen (54.17% patients had excellent results, six (25% patients had good results, four (1 6.67% patients had fair results and one (4.16 patient had poor result. CONCLUSION: Unreamed interlocking intramedullary nailing with the help of image intensifier seems feasible in open diaphyseal fractures of tibia with the advantages of minimal blood l oss, low risk of infection, early mobilisation , earlier soft tissue coverage , Promotes early union , minimal hospital stay and early returns to activities

  6. Reviewed approach to defining the Active Interlock Envelope for Front End ray tracing

    Energy Technology Data Exchange (ETDEWEB)

    Seletskiy, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Shaftan, T. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-09-24

    To protect the NSLS-II Storage Ring (SR) components from damage from synchrotron radiation produced by insertion devices (IDs) the Active Interlock (AI) keeps electron beam within some safe envelope (a.k.a Active Interlock Envelope or AIE) in the transverse phase space. The beamline Front Ends (FEs) are designed under assumption that above certain beam current (typically 2 mA) the ID synchrotron radiation (IDSR) fan is produced by the interlocked e-beam. These assumptions also define how the ray tracing for FE is done. To simplify the FE ray tracing for typical uncanted ID it was decided to provide the Mechanical Engineering group with a single set of numbers (x,x’,y,y’) for the AIE at the center of the long (or short) ID straight section. Such unified approach to the design of the beamline Front Ends will accelerate the design process and save valuable human resources. In this paper we describe our new approach to defining the AI envelope and provide the resulting numbers required for design of the typical Front End.

  7. Outcomes in closed reamed interlocking nail in fractures of shaft of femur

    International Nuclear Information System (INIS)

    Mohammad, T.; Sawati, A.; Ahmed, A.

    2015-01-01

    Femoral shaft fracture is one of the common fractures seen in accident and emergency department of our hospital. Violent forces are required to break this and strongest of human bones. There are various treatment modalities for femoral shaft fractures in adults like traction, brace, platting, intramedullary nail (IMN), external fixators and inter locking nails. The study was done with an objective to evaluate the results of closed reamed interlocking nail in fractures of shaft of femur. Methods: A prospective study of 114 cases of femoral shaft fractures was carried out at orthopaedic unit of Ayub Teaching Hospital Abbottabad during 1 year. All these cases were treated with statically locked nails under spinal or general anaesthesia. These cases were followed up for up to one year and Results of the interlocking nail were observed in terms of union and complications. Results: Out of 114 patients, 95 underwent union in 90-150 days with a mean of 110.68 days. Ten patients had dynamization within six weeks because of obvious fracture gap in radiograph. There were 3 patients who had non-union, and 6 patients had delayed union which was treated with dynamization. Conclusion: Close reamed interlocking intramedullary nail in femoral shaft fractures is the treatment of choice. Patient rehabilitation is early, hospitalization is short, and fracture healing response is good. (author)

  8. OUTCOMES IN CLOSED REAMED INTERLOCKING NAIL IN FRACTURES OF SHAFT OF FEMUR.

    Science.gov (United States)

    Mohammad, Taj; Khan, Alamzeb; Sawati, Alamzeb; Ahmed, Ashfaq; Awan, Abdus Saboor; Saboor, Abdus; Siddique

    2015-01-01

    Femoral shaft fracture is one of the common fractures seen in accident and emergency department of our hospital. Violent forces are required to break this and strongest of human bones. There are various treatment modalities for femoral shaft fractures in adults like traction, brace, platting, intramedullary nail (IMN), external fixators and inter locking nails. The study was done with an objective to evaluate the results of closed reamed interlocking nail in fractures of shaft of femur. A prospective study of 114 cases of femoral shaft fractures was carried out at orthopaedic unit of Ayub Teaching Hospital Abbottabad during 1 year. All these cases were treated with statically locked nails under spinal or general anaesthesia. These cases were followed up for up to one year and Results of the interlocking nail were observed in terms of union and complications. Out of 114 patients, 95 underwent union in 90-150 days with a mean of 110.68 days. Ten patients had dynamization within six weeks because of obvious fracture gap in radiograph. There were 3 patients who had non-union, and 6 patients had delayed union which was treated with dynamization. Close reamed interlocking intramedullary nail in femoral shaft fractures is the treatment of choice. Patient rehabilitation is early, hospitalization is short, and fracture healing response is good.

  9. Comparison of non-compression and compression interlocking intramedullary nailing in rabbit femoral shaft osteotomy model.

    Science.gov (United States)

    Baki, Mehmet Emre; Aldemir, Cengiz; Duygun, Fatih; Doğan, Ali; Kerimoğlu, Gökçen

    2017-04-01

    This study aims to compare non-compression and compression intramedullary nailing in an experimental femoral shaft osteotomy model in terms of radiological, histological, and biomechanical aspects. Twenty-four white New Zealand rabbits (average weight 4.3 kg; range 4 to 4.8 kg) were divided into three groups. A right femoral osteotomy was performed in all rabbits and all femurs were fixed with titanium compression interlocking intramedullary nail. After locking of nails, no compression was performed in group 1 while 0.5 mm and 1 mm compressions were performed in group 2 and 3, respectively. All rabbits were sacrificed four weeks after operation. Fracture sites were examined histologically and radiologically. Finite element analyses were performed. Radiological scores of groups 2 and 3 were significantly higher than group 1. There was no significant difference between groups 2 and 3 radiologically. Best histological scores were achieved in group 2. According to finite element analyses, osteotomy site in group 2 was exposed to 1240 N of load and 34.5 MPa of mean stress. Compression interlocking intramedullary nailing provides faster fracture healing than non-compression interlocking intramedullary nailing. Best histological fracture healing scores were obtained with 0.5 mm compression performed at the fracture site.

  10. Bio-inspired design of geometrically interlocked 3D printed joints

    Science.gov (United States)

    Kumar, S.; Oliva, Noel; Kumar's Lab Team

    The morphology of the adhesive-adherend interface significantly affects the mechanical behavior of adhesive joints. As seen in some biocomposites like human skull, or the nacre of some bivalve molluscs' shells, a geometrically interlocking architecture of interfaces creates toughening and strengthening mechanisms enhancing the mechanical properties of the joint. In an attempt to characterize this mechanical interlocking mechanism, this study is focused on computational and experimental investigation of a single-lap joint with a very simple geometrically interlocked interface design in which both adherends have a square waveform configuration of the joining surfaces. This square waveform configuration contains a positive and a negative rectangular teeth per cycle in such a way that the joint is symmetric about the mid-bondlength. Both physical tests performed on 3D printed prototypes of joints and computational results indicate that the joints with square waveform design have higher strength and damage tolerance than those of joints with flat interface. In order to identify an optimal design configuration of this interface, a systematic parametric study is conducted by varying the geometric and material properties of the non-flat interface. This work was supported by Lockheed Martin (Award No: 12NZZ1).

  11. Model-Based Engineering and Manufacturing CAD/CAM Benchmark

    International Nuclear Information System (INIS)

    Domm, T.D.; Underwood, R.S.

    1999-01-01

    than a single computer-aided manufacturing (CAM) system. The Inteznet was a technology that all companies were considering to either transport information more easily throughout the corporation or as a conduit for business, as the small firm was doing Successfully. Because PrdEngineer is the de facto CAD standard fbr the NWC, the Benchmark Team targeted companies using Parametric Technology Corporation (PTC) software tools. Most of the companies used Pm'Engineer for design to some degree, but found the PTC CAM product, PdManufacture lacking as compared to alternate CAM solutions. All of the companies visited found the data exchange between CAD/CAM systems problematic. It was apparent that these companies were trying to consolidate their software tools to reduce translation but had not been able to do so because no single solution had all the needed capabilities. In regard to organizational structure and human resources, two companies were found to be using product or program teams. These teams consisted of the technical staff capable of completing the entire task and were xmintained throughout the project. This same strategy was evident at another of the companies but with more mobility of members. For all companies visited except the small work structure breakdown and responsibility were essentially the same as Y-12's at this time. The functions of numerical control (NC), desi and process planning were separate and distinct. The team made numerous recommendations that are detailed in the report

  12. The Secondary Standards Programme for OmegaCAM

    NARCIS (Netherlands)

    Verdoes Kleijn, G.; Vermeij, R.; Valentijn, E.; Kuijken, K.; Sterken, C.

    2007-01-01

    The OmegaCAM wide-field imager will start operations at the ESO VLT Survey Telescope at Paranal in 2007. The photometric calibration of OmegaCAM data depends on standard-star measurements that cover the complete 1°×1° FOV. A catalog fullfilling this requirement for 8 Landolt equatorial fields,

  13. The use of economic evaluation in CAM: an introductory framework

    Directory of Open Access Journals (Sweden)

    Adams Jon

    2010-11-01

    Full Text Available Abstract Background For CAM to feature prominently in health care decision-making there is a need to expand the evidence-base and to further incorporate economic evaluation into research priorities. In a world of scarce health care resources and an emphasis on efficiency and clinical efficacy, CAM, as indeed do all other treatments, requires rigorous evaluation to be considered in budget decision-making. Methods Economic evaluation provides the tools to measure the costs and health consequences of CAM interventions and thereby inform decision making. This article offers CAM researchers an introductory framework for understanding, undertaking and disseminating economic evaluation. The types of economic evaluation available for the study of CAM are discussed, and decision modelling is introduced as a method for economic evaluation with much potential for use in CAM. Two types of decision models are introduced, decision trees and Markov models, along with a worked example of how each method is used to examine costs and health consequences. This is followed by a discussion of how this information is used by decision makers. Conclusions Undoubtedly, economic evaluation methods form an important part of health care decision making. Without formal training it can seem a daunting task to consider economic evaluation, however, multidisciplinary teams provide an opportunity for health economists, CAM practitioners and other interested researchers, to work together to further develop the economic evaluation of CAM.

  14. The unstoppable progress of CAD/CAM - Results and prospects

    Science.gov (United States)

    Seifert, H.

    1982-08-01

    The state of CAD/CAM technology in the construction and machinery industries is clarified by means of a few examples using PROREN software. The use of CAD in both two-dimensional and three-dimensional design is discussed, and CAD/CAM's potential for determining control information for numerically controlled milling is assessed. The design of parts by CAD is pictorially shown.

  15. Triple Helix Model in Developing Technological Innovation: The Case of Computer Based Interlocking

    Directory of Open Access Journals (Sweden)

    Erry Ricardo Nurzal

    2013-01-01

    Full Text Available Computer Based Interlocking (CBI is the most important part of the electric railway signalingsystem which serves as the “brain” that controls the operation of electrical signaling system thatreplaces the role of the electromagnetic relay which has gradually been abandoned. Developmentof CBI is based on the fact that until recently the signaling system in Indonesia is still reliedheavily on the CBI products from foreign vendors. Therefore, the development of domestic CBIproducts is really necessary in order to decrease the dependence on technology from foreignvendors that at the same time is also be able to support the accelerated development of railwayinfrastructure in Indonesia.The CBI development is conducted in the form of a collaboration involving the government,universities, and industry. This paper explores and analyzes the roles and interactions betweendifferent actors in the triple helix perspective, and identifies how the innovation ecosystemfunctioning with support from the government.Based on the data collected through in-depth interview with the actors involved in the CBI casestudy, this paper gives some key findings. First, government role is very important in establishingan innovation ecosystem for CBI development. Second, the leader in the development of CBItechnological innovation should be the industry supported by governmental R & D institutionsand universities. Third, R & D consortium is an effective vehicle for creating an interactionamong industry, academia, and government.Such findings may provide conceptual direction which is important for the development oftechnological innovation in Indonesia. In addition, in providing support for R&D activities, thegovernment needs to direct its R & D incentives to the industry as a business practitioner with itsown technology roadmap. The possible further research may include some research issues. First,is the pattern occurred in the CBI case also applied in the other cases of

  16. Accuracy of CAD-CAM-fabricated removable partial dentures.

    Science.gov (United States)

    Arnold, Christin; Hey, Jeremias; Schweyen, Ramona; Setz, Jürgen M

    2018-04-01

    The conventional fabrication of removable partial dentures (RPDs) is a complex, error-prone, time-consuming, and expensive process. The use of computer-aided design and computer-aided manufacturing (CAD-CAM) techniques, especially rapid prototyping, promises a more effective method for fabricating RPD frameworks. The purpose of this in vitro study was to evaluate the fit of RPD clasps fabricated by means of 4 different CAD-CAM-systems and to compare those fittings with that of the conventional lost-wax casting technique (LWT). A master model of a partially edentulous maxilla with the canines and second molars as the remaining teeth was fabricated. After the model was optically scanned, we designed a quadrangularly supported RPD with 4 clasps and a palatal strap major connector. A standard tessellation language data set was used to fabricate 12 identical RPDs by using 4 different CAD-CAM techniques: indirect rapid prototyping (wax inject printing combined with LWT), direct rapid prototyping (selective laser melting), indirect milling (wax milling with LWT), and direct milling (resin milling [polyetheretherketone]). Three conventionally cast RPDs (LWT) served as the control group. The fit accuracy of the clasps (n=12 for each group) was determined in both the horizontal and vertical dimensions by using light microscopy. Indirectly milled RPDs (117 ±34 μm horizontal and 45 ±21 μm vertical) and directly milled RPDs (43 ±23 μm horizontal, and 38 ±21 μm vertical) showed significantly better (P<.05) fit than did conventionally fabricated LWT RPDs (133 ±59 μm horizontal; 73 ±25 μm vertical). The worst fit was found for RPDs fabricated using indirect rapid prototyping (323 ±188 μm horizontal and 112 ±60 μm vertical) or direct rapid prototyping (365 ±205 μm horizontal and 363 ±133 μm vertical), which were unstable on the master model, making them unsuitable for clinical use. Most RPDs exhibited smaller vertical measuring distances. Compared with the LWT

  17. Reinforcing the role of the conventional C-arm - a novel method for simplified distal interlocking

    Directory of Open Access Journals (Sweden)

    Windolf Markus

    2012-01-01

    Full Text Available Abstract Background The common practice for insertion of distal locking screws of intramedullary nails is a freehand technique under fluoroscopic control. The process is technically demanding, time-consuming and afflicted to considerable radiation exposure of the patient and the surgical personnel. A new concept is introduced utilizing information from within conventional radiographic images to help accurately guide the surgeon to place the interlocking bolt into the interlocking hole. The newly developed technique was compared to conventional freehand in an operating room (OR like setting on human cadaveric lower legs in terms of operating time and radiation exposure. Methods The proposed concept (guided freehand, generally based on the freehand gold standard, additionally guides the surgeon by means of visible landmarks projected into the C-arm image. A computer program plans the correct drilling trajectory by processing the lens-shaped hole projections of the interlocking holes from a single image. Holes can be drilled by visually aligning the drill to the planned trajectory. Besides a conventional C-arm, no additional tracking or navigation equipment is required. Ten fresh frozen human below-knee specimens were instrumented with an Expert Tibial Nail (Synthes GmbH, Switzerland. The implants were distally locked by performing the newly proposed technique as well as the conventional freehand technique on each specimen. An orthopedic resident surgeon inserted four distal screws per procedure. Operating time, number of images and radiation time were recorded and statistically compared between interlocking techniques using non-parametric tests. Results A 58% reduction in number of taken images per screw was found for the guided freehand technique (7.4 ± 3.4 (mean ± SD compared to the freehand technique (17.6 ± 10.3 (p p = 0.001. Operating time per screw (from first shot to screw tightened was on average 22% reduced by guided freehand (p = 0

  18. Treatment Preferences for CAM in Children with Chronic Pain

    Directory of Open Access Journals (Sweden)

    Jennie C. I. Tsao

    2007-01-01

    Full Text Available CAM therapies have become increasingly popular in pediatric populations. Yet, little is known about children's preferences for CAM. This study examined treatment preferences in chronic pediatric pain patients offered a choice of CAM therapies for their pain. Participants were 129 children (94 girls (mean age = 14.5 years ± 2.4; range = 8–18 years presenting at a multidisciplinary, tertiary clinic specializing in pediatric chronic pain. Bivariate and multivariate analyses were used to examine the relationships between CAM treatment preferences and patient's sociodemographic and clinical characteristics, as well as their self-reported level of functioning. Over 60% of patients elected to try at least one CAM approach for pain. The most popular CAM therapies were biofeedback, yoga and hypnosis; the least popular were art therapy and energy healing, with craniosacral, acupuncture and massage being intermediate. Patients with a diagnosis of fibromyalgia (80% were the most likely to try CAM versus those with other pain diagnoses. In multivariate analyses, pain duration emerged as a significant predictor of CAM preferences. For mind-based approaches (i.e. hypnosis, biofeedback and art therapy, pain duration and limitations in family activities were both significant predictors. When given a choice of CAM therapies, this sample of children with chronic pain, irrespective of pain diagnosis, preferred non-invasive approaches that enhanced relaxation and increased somatic control. Longer duration of pain and greater impairment in functioning, particularly during family activities increased the likelihood that such patients agreed to engage in CAM treatments, especially those that were categorized as mind-based modalities.

  19. Treatment Preferences for CAM in children with chronic pain.

    Science.gov (United States)

    Tsao, Jennie C I; Meldrum, Marcia; Kim, Su C; Jacob, Margaret C; Zeltzer, Lonnie K

    2007-09-01

    CAM therapies have become increasingly popular in pediatric populations. Yet, little is known about children's preferences for CAM. This study examined treatment preferences in chronic pediatric pain patients offered a choice of CAM therapies for their pain. Participants were 129 children (94 girls) (mean age = 14.5 years +/- 2.4; range = 8-18 years) presenting at a multidisciplinary, tertiary clinic specializing in pediatric chronic pain. Bivariate and multivariate analyses were used to examine the relationships between CAM treatment preferences and patient's sociodemographic and clinical characteristics, as well as their self-reported level of functioning. Over 60% of patients elected to try at least one CAM approach for pain. The most popular CAM therapies were biofeedback, yoga and hypnosis; the least popular were art therapy and energy healing, with craniosacral, acupuncture and massage being intermediate. Patients with a diagnosis of fibromyalgia (80%) were the most likely to try CAM versus those with other pain diagnoses. In multivariate analyses, pain duration emerged as a significant predictor of CAM preferences. For mind-based approaches (i.e. hypnosis, biofeedback and art therapy), pain duration and limitations in family activities were both significant predictors. When given a choice of CAM therapies, this sample of children with chronic pain, irrespective of pain diagnosis, preferred non-invasive approaches that enhanced relaxation and increased somatic control. Longer duration of pain and greater impairment in functioning, particularly during family activities increased the likelihood that such patients agreed to engage in CAM treatments, especially those that were categorized as mind-based modalities.

  20. Complementary and alternative medicine (CAM providers’ views of chronic low back pain patients’ expectations of CAM therapies: a qualitative study

    Directory of Open Access Journals (Sweden)

    Schafer Lisa M

    2012-11-01

    Full Text Available Abstract Background Some researchers think that patients with higher expectations for CAM therapies experience better outcomes and that enthusiastic providers can enhance treatment outcomes. This is in contrast to evidence suggesting conventional medical providers often reorient patient expectations to better match what providers believe to be realistic. However, there is a paucity of research on CAM providers’ views of their patients’ expectations regarding CAM therapy and the role of these expectations in patient outcomes. Methods To better understand how CAM providers view and respond to their patients’ expectations of a particular therapy, we conducted 32 semi-structured, qualitative interviews with acupuncturists, chiropractors, massage therapists and yoga instructors identified through convenience sampling. Interviews were recorded, transcribed and analyzed thematically using Atlas ti version 6.1. Results CAM providers reported that they attempt to ensure that their patients’ expectations are realistic. Providers indicated they manage their patients’ expectations in a number of domains— roles and responsibilities of providers and patients, treatment outcomes, timeframe for improvement, and treatment experience. Providers reported that patients’ expectations change over time and that they need to continually manage these expectations to enhance patient engagement and satisfaction with treatment. Conclusions Providers of four types of CAM therapies viewed patients’ expectations as an important component of their experiences with CAM therapy and indicated that they try to align patient expectations with reality. These findings suggest that CAM providers are similar in this respect to conventional medical providers.

  1. Complementary and alternative medicine (CAM) providers' views of chronic low back pain patients' expectations of CAM therapies: a qualitative study.

    Science.gov (United States)

    Schafer, Lisa M; Hsu, Clarissa; Eaves, Emery Rose; Ritenbaugh, Cheryl; Turner, Judith; Cherkin, Daniel C; Sims, Colette; Sherman, Karen J

    2012-11-27

    Some researchers think that patients with higher expectations for CAM therapies experience better outcomes and that enthusiastic providers can enhance treatment outcomes. This is in contrast to evidence suggesting conventional medical providers often reorient patient expectations to better match what providers believe to be realistic. However, there is a paucity of research on CAM providers' views of their patients' expectations regarding CAM therapy and the role of these expectations in patient outcomes. To better understand how CAM providers view and respond to their patients' expectations of a particular therapy, we conducted 32 semi-structured, qualitative interviews with acupuncturists, chiropractors, massage therapists and yoga instructors identified through convenience sampling. Interviews were recorded, transcribed and analyzed thematically using Atlas ti version 6.1. CAM providers reported that they attempt to ensure that their patients' expectations are realistic. Providers indicated they manage their patients' expectations in a number of domains- roles and responsibilities of providers and patients, treatment outcomes, timeframe for improvement, and treatment experience. Providers reported that patients' expectations change over time and that they need to continually manage these expectations to enhance patient engagement and satisfaction with treatment. Providers of four types of CAM therapies viewed patients' expectations as an important component of their experiences with CAM therapy and indicated that they try to align patient expectations with reality. These findings suggest that CAM providers are similar in this respect to conventional medical providers.

  2. Machinability of CAD-CAM materials.

    Science.gov (United States)

    Chavali, Ramakiran; Nejat, Amir H; Lawson, Nathaniel C

    2017-08-01

    Although new materials are available for computer-aided design and computer-aided manufacturing (CAD-CAM) fabrication, limited information is available regarding their machinability. The depth of penetration of a milling tool into a material during a timed milling cycle may indicate its machinability. The purpose of this in vitro study was to compare the tool penetration rate for 2 polymer-containing CAD-CAM materials (Lava Ultimate and Enamic) and 2 ceramic-based CAD-CAM materials (e.max CAD and Celtra Duo). The materials were sectioned into 4-mm-thick specimens (n=5/material) and polished with 320-grit SiC paper. Each specimen was loaded into a custom milling apparatus. The apparatus pushed the specimens against a milling tool (E4D Tapered 2016000) rotating at 40 000 RPM with a constant force of 0.98 N. After a 6-minute timed milling cycle, the length of each milling cut was measured with image analysis software under a digital light microscope. Representative specimens and milling tools were examined with scanning electron microscopy (SEM) and energy dispersive x-ray spectroscopy. The penetration rate of Lava Ultimate (3.21 ±0.46 mm/min) and Enamic (2.53 ±0.57 mm/min) was significantly greater than that of e.max CAD (1.12 ±0.32 mm/min) or Celtra Duo (0.80 ±0.21 mm/min) materials. SEM observations showed little tool damage, regardless of material type. Residual material was found on the tools used with polymer-containing materials, and wear of the embedding medium was seen on the tools used with the ceramic-based materials. Edge chipping was noted on cuts made in the ceramic-based materials. Lava Ultimate and Enamic have greater machinability and less edge chipping than e.max CAD and Celtra Duo. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  3. I: Hydrodynamic-focusing microreactor II: Mechanically interlocked molecules for functional materials

    Science.gov (United States)

    Coti, Karla Karina

    I: Microreactors, a class of microfluidics, offer numerous benefits -- such as small sample requirement, short analysis times and automations -- and have been used to study reactions of chemical and biological reagents. In order to understand the relationship between fast mixing, product regioselectivity, as well as the ability to separate, in time and space, the nanoparticle (NP) formation stages, a microreactor capable of fast and controllable mixing was developed (Chapter 1) based on multi-lamination and hydrodynamic-focusing. By taking advantage of the fast and controllable mixing properties of this novel microreactor one can control the time when chemical reactions commence inside the microchannels. These properties of the microreactor can be exploited to improve the product regioselectivity of a diazo-coupling reaction to attain a product distribution of monoazo to diazo product of ˜1:99, a selectivity unprecedented in both conventional, macroscopic reactors and other microfluidic systems. Additionally, the ability to separate different stages during the NP formation process inside the microreactor, allowed us to study the aggregation of polypyrrole NPs. II: Supramolecular actuators and molecular interlocked molecules, such as catenanes and rotaxanes, have attracted considerable attention because of their sophisticated topology and their application in functional molecular devices. The blending of supramolecular and mechanostereochemistry with mesoporous silica NPs has proven to be a powerful combination, leading to the development of a new class of materials -- mechanized silica nanoparticles ( Chapter 2). These new hybrid materials are designed to release their content in response to an external stimuli and their development is being driven by the need to improve current drug delivery technologies. In an effort to explore how the stimuli-controlled mechanical movement of switchable, bistable [2]rotaxanes -- based on a cyclobis(paraquat-p-phenylene) ring

  4. Interlocking Directorships in Polish Joint Stock Companies = Medsebojna prepletenost članov nadzornih svetov v delniških družbah na Poljskem

    OpenAIRE

    Marek Pawlak

    2008-01-01

    Studies concerning interlocking directorships have been carried out among Polish joint stock corporations. The main source of data have been the announcements that are to be published by corporations regularly in a journal called Business and Court Gazette (BCG). Interlocking directorships constitute a network among corporations the use of which enables co-ordinated management of the whole group. The phenomenon of interlocking directorships in Polish joint stock companies can be compared to t...

  5. Bond strength of novel CAD/CAM restorative materials to self-adhesive resin cement: the effect of surface treatments.

    Science.gov (United States)

    Elsaka, Shaymaa E

    2014-12-01

    To evaluate the effect of different surface treatments on the microtensile bond strength (μTBS) of novel CAD/CAM restorative materials to self-adhesive resin cement. Two types of CAD/CAM restorative materials (Vita Enamic [VE] and Lava Ultimate [LU]) were used. The specimens were divided into five groups in each test according to the surface treatment performed; Gr 1 (control; no treatment), Gr 2 (sandblasted [SB]), Gr 3 (SB+silane [S]), Gr 4 (hydrofluoric acid [HF]), and Gr 5 (HF+S). A dual-curing self-adhesive resin cement (Bifix SE [BF]) was applied to each group for testing the adhesion after 24 h of storage in distilled water or after 30 days using the μTBS test. Following fracture testing, specimens were examined with a stereomicroscope and SEM. Surface roughness and morphology of the CAD/CAM restorative materials were characterized after treatment. Data were analyzed using ANOVA and Tukey's test. The surface treatment, type of CAD/CAM restorative material, and water storage periods showed a significant effect on the μTBS (p0.05). On the other hand, for the VE/BF system, surface treatment with HF+S showed higher bond strength values compared with SB and HF surface treatments (pmaterials was modified after treatments. The effect of surface treatments on the bond strength of novel CAD/CAM restorative materials to resin cement is material dependent. The VE/BF CAD/CAM material provided higher bond strength values compared with the LU/BF CAD/CAM material.

  6. Comparative study of RetCamRetCam II vs. binocular ophthalmoscopy in a screening program for retinopathy of prematurity.

    Science.gov (United States)

    Tejada-Palacios, P; Zarratea, L; Moral, M; de la Cruz-Bértolo, J

    2015-08-01

    To determine the performance of RetCam vs. binocular ophthalmoscopy (BIO) in a screening program for retinopathy of prematurity (ROP). Observational comparative study with prospective data collection. Examinations with RetCam (n=169) were performed on 83 infants included in a screening program for ROP and stored for analysis at a later stage. An experienced ophthalmologist examined the ocular fundus with binocular indirect ophthalmoscopy (BIO). The RetCam images were assessed for the presence of ROP, zone, grade, and presence of plus disease. RetCam and BIO data were compared by visually to estimate sensitivity, specificity, positive (VPP) and negative (VPN) predictive values. ROP disease was detected in 108 eyes with BIO, and in 74 with RetCam. Out of 306 eyes examined with RetCam, false negative results were found in 34 eyes, with no false positives. Sensitivity of RetCam exam vs. BIO was 0.68, and specificity was 0.99. Positive predictive value was 0.93 and negative predictive value was 0.85. All 34 ROP cases not detected with RetCam were in zone III or outer zone II. They were all mild and regressed spontaneously. No threshold ROP was missed with RetCam. Binocular indirect ophthalmoscopy is the reference method for the diagnosis of ROP. RetCam may be used as an alternative for ROP screening. Copyright © 2010 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.

  7. EMC Specific Problems of Frequency Converters Used at Interlocking Device

    Directory of Open Access Journals (Sweden)

    J. Novak

    2009-12-01

    Full Text Available The paper deals with problems of electromagnetic compatibility (EMC of frequency control drive of electromotive switch actuator of railway switch. The frequency converter with Pulse Width Modulation (PWM and the output sinus filter are used for feeding of the asynchronous motor of the switch actuator. This drive is operated in an insulated system of feeding voltages. The drive is fed by a frequency converter with an unshielded cable with length up to 1.2 km. The EMC problems occurring at development and operating of the drive are analyzed in this paper. The used solution of these problems and experience with EMC of the given system from real operation are described in this paper as well.

  8. The Photo-3 model: A Python-based model for C3, C4, and CAM photosynthesis coupled with environmental conditions

    Science.gov (United States)

    Hartzell, S. R.; Bartlett, M. S., Jr.; Porporato, A. M.

    2017-12-01

    The ability to depict all three photosynthetic types (C3, C4, and CAM) has important implications for the study of both natural and agroecosystems. Currently no model exists which covers all types of photosynthesis in a consistent way and which can be fully integrated with environmental conditions. This is partially because, despite the fact that Crassulacean acid metabolism (CAM) photosynthesis is prevalent in many plants in arid and semi-arid ecosystems, where it may comprise nearly 50% of all plant biomass, CAM modelling remains understudied. The Photo-3 model takes advantage of recent advances in mechanistic modeling of CAM photosynthesis to provide a direct comparison of CAM functioning with C3 and C4 functioning under a wide range of soil and atmospheric conditions. The model is based on a core Farquhar photosynthetic model with additional functions to represent the spatial and temporal separations of carbon uptake and assimilation in the case of C4 and CAM photosynthesis. We have parameterized the model for one representative species of each photosynthetic type: Opuntia ficus-indica (CAM), Sorghum bicolor (C4), and Triticum aestivum (C3). Results agree well with experimental data on carbon assimilation and water use for the three species. Model runs using climate data from Temple, TX; Sicily, Italy; Zacatecas, Mexico; Pernambuco, Brazil and Adias Ababa, Ethiopia illustrate the high water use efficiency of CAM plants and its cumulative effects on long-term productivity in water-limited environments. The Photo-3 model, which is written in Python, will be made publicly available on GitHub and its outputs may be coupled to existing models of plant growth and phenology. The model may be used to evaluate potential productivity and water use for C3, C4, and CAM plants, and to devise optimal strategies for cropping systems and irrigation in water-limited environments.

  9. Incidence of Varus Malalignment Post Interlocking Nail in Proximal Femur Shaft Fractures Comparing Two Types of Entry Points.

    Science.gov (United States)

    Sadagatullah, A N; Nazeeb, M N; Ibrahim, S

    2017-11-01

    Introduction: Osteosynthesis of the femur using an interlocking nail is the gold standard for treating diaphyseal fractures of the femur. There are two established entry points for the antegrade interlocking nails which is the piriformis fossa or the greater trochanter. It has been reported that varus malalignment was frequently seen in proximal femur fracture which were treated with interlocking nail utilizing the greater trochanter entry point. The study was done to find out if the problem was of significance. Materials and Methods: This was a retrospective study which included 179 patients with femur fractures which were treated from January 2013 till September 2015 in one Hospital. They were treated with interlocking nail either by utilizing the piriformis fossa (PF) or the greater trochanter (GT) entry points. Post-operative radiographs of the femur were used to measure the varus deformity. Results: Out of 179 patients, there were 5 patients who were reported to have unacceptable varus malalignment (2.79%). These 5 patients were out of the 88 (5.68%) patients utilizing the greater trochanter as the entry point. The same 5 patients were out 90 patients that were diagnosed with proximal femur shaft fractures (5.55%). Analysis with logistic regression was statistically not significant. Conclusion: There was higher rate of varus malalignment seen in proximal femur shaft fractures treated with interlocking nails utilizing the greater trochanter entry point. The incidence of varus malalignment was not significant statistically.

  10. A comparative study of interlocking directorates at the end of the import-substituting industrialization period in Argentina and Chile

    Directory of Open Access Journals (Sweden)

    Erica Salvaj, Andrea Lluch

    2012-12-01

    Full Text Available Research on interlocking directorates has been conducted primarily in the United States and European countries. Little work of either theoretical or empirical nature has been done to study the characteristics and the factors that affect this important business network in peripheral and turbulent economies. In this comparative and historical study, we focus on the effect of the political and economic turbulence and the ownership composition of the largest firms on shaping the structure of interlocking directorates in Argentina and Chile by the end of the sixties. Four main findings result from this analysis: 1 the interlocking directorate in Argentina is more fragmented than in Chile; 2 most relevant actors in the directorship interlock in Argentina are firms in industries considered strategic by the government; 3 multinational subsidiaries occupy a central position in Argentina; 4 banks and firms owned by local business groups played a central role in the interlocking directorates in Chile. This study shows how the institutional and economic factors shape the structure of relations between companies.

  11. Evaluation of thickness of CAD/CAM fabricated zirconia cores by digital microscope.

    Science.gov (United States)

    Habib, Syed Rashid; Otaibi, Asim Khaled Al; Anazi, Talal Ali Al; Anazi, Samer Mosleh Al

    2018-01-01

    Despite several advantages of digitalized workflow, researchers have noted discrepancies in the precision and trueness. This study investigated the accuracy in the final thickness of Zirconia (Zr) cores fabricated by five CAD/CAM systems. Standardized manufacturing of the cores with 1 mm thickness were carried out. Cores were then sectioned into two halves and measurement made with Digital Microscope at 5 points in micrometers. Overall, mean thickness for the groups was 1048.81 ± 94.01, which was 48 μm higher than the thickness programmed in the software. Anova showed a statistically significant difference between the groups (p= 0.000). Presence of variations in the thickness and 5 measurement points for the CAD/CAM systems investigated was found. No significant difference was observed and the thickness of the cores were within acceptable level.

  12. Validation of a Criterion for Cam Mechanisms Optimization Using Constraints upon Cam’s Curvature

    Directory of Open Access Journals (Sweden)

    Stelian Alaci

    2016-06-01

    Full Text Available For the mechanism with rotating cam and knife-edge follower, an optimization criterion by means of imposed constraints upon cam’s curvature is expressed in a special coordinate system. Thus, stating the optimization criterion in the coordinate system defined by the mechanisms constructive parameters -eccentricity and minimum follower’s stroke, a contour is obtained for any position of the mechanism. The optimization criterion assumes establishing the position of the characteristic point of the mechanism with respect to this contour. Fulfillment of optimization criterion assumes that the characteristic point is positioned in the same manner with respect to all contours. The optimization criterion is simplified when considering the envelope of the contours. The method is exemplified using two mechanisms, with the cams priori satisfying the criterion.

  13. Utilizing optical coherence tomography for CAD/CAM of indirect dental restorations

    Science.gov (United States)

    Chityala, Ravishankar; Vidal, Carola; Jones, Robert

    Optical Coherence Tomography (OCT) has seen broad application in dentistry including early carious lesion detection and imaging defects in resin composite restorations. This study investigates expanding the clinical usefulness by investigating methods to use OCT for obtaining three-dimensional (3D) digital impressions, which can be integrated to CAD/CAM manufacturing of indirect restorations. 3D surface topography `before' and `after' a cavity preparation was acquired by an intraoral cross polarization swept source OCT (CP-OCT) system with a Micro-Electro-Mechanical System (MEMS) scanning mirror. Image registration and segmentation methods were used to digitally construct a replacement restoration that modeled the original surface morphology of a hydroxyapatite sample. After high resolution additive manufacturing (e.g. polymer 3D printing) of the replacement restoration, micro-CT imaging was performed to examine the marginal adaptation. This study establishes the protocol for further investigation of integrating OCT with CAD/CAM of indirect dental restorations.

  14. Comparative study between reamed versus unreamed interlocking intramedullary nailing in compound fractures of shaft tibia

    Directory of Open Access Journals (Sweden)

    Subhash Puri

    2013-01-01

    Full Text Available Background: Tibia is the commonest bones to sustain open injury because of subcutaneous position. Treatment of open fractures requires simultaneous management of both skeletal and soft tissue injury. Intramedullary nailing with reaming is generally considered to be contraindicated for open fractures tibia, because it damages the endosteal blood supply which will lead to non-union, deep infection. However, recent studies with or without reaming in open fracture tibia shows no influence in healing of fracture. Purpose: To compare the clinical and radiological results of intramedullary interlocking nailing of open fractures of the tibial shaft after reaming versus unreamed medullary canal. Materials and Methods: Between 2008 and 2011, we have treated 40 patients with compound tibia fracture (type I, II, IIIA by simultaneous care of wound and skeletal injury. Primary fixation for fracture stabilization was done by closed intramedullary interlock nailing either reamed or unreamed; the allocation to the two groups made on alternating basis. Wound was managed by thorough debridement with primary/delayed primary closure by suturing, split thickness skin grafting or fasciocutaneous flap cover. Active, non-weight bearing exercises were started from next post-op day. Partial weight bearing after suture removal was started on 12 th day. Further follow-up was done at 6 weeks interval for union. Results: Open fractures of shaft of tibia treated with unreamed/reamed interlocking nailing gave excellent results. In present series, 19 fractures (95% treated by unreamed and 19 (95% fractures treated by reamed technique, united within 6 months of injury. Delay in union was noticed in one patient treated by unreamed technique who had segmental and extensive soft tissue injury and in reamed nailing there was one patient with deep infection, which was treated with antibiotic coated nail. Conclusion: Time to complete union was similar in both groups. Adequate

  15. Intramedullary nailing without interlocking screws for femoral and tibial shaft fractures.

    Science.gov (United States)

    Kreb, Dieuwertje L; Blokhuis, Taco J; van Wessem, Karlijn J P; Bemelman, Mike; Lansink, Koen W W; Leenen, Luke P H

    2013-08-01

    Intramedullary fixation is the treatment of choice for diaphyseal fractures of the femur and tibia. Locking the implant can sometimes be cumbersome and time consuming. In our institution, fractures with axial and rotational stability are treated with intramedullary nailing without interlocking. All consecutive patients presented in the University Medical Center Utrecht from October 2003 to August 2009 with acute traumatic diaphyseal fractures of the tibia or femur that were considered axial and rotational stable were included. They underwent internal fixation using intramedullary nails without interlocking. Patient records were evaluated for duration of surgery, perioperative complications, consolidation time and re-operations. Twenty-nine long bone fractures were treated in 27 patients: 20 men and 7 women, with an average age of 28.9 years (range 15.6-54.4). There were 12 femoral fractures and 17 tibial fractures. Sixteen fractures were closed and 13 were open (10 Gustilo 1, 3 Gustilo 2). The mean operating time was 43 min (range 18-68 min) for tibial fractures and 55 min (range 47-150 min) for femoral fractures. Postoperative complications occurred in six patients. Two patients (three fractures) were lost to follow-up. Healing occurred in 25 of the 26 remaining fractures (96 %) without additional interventions. One tibia was secondarily converted to a standard locked nail because of axial and rotational instability. All patients returned to their pre-injury level of activity. The use of intramedullary nailing without interlocking is associated with minimal complications in selected fractures. The advantages include a short operating time and the simplicity of its application.

  16. Protocol of thermal treatments for the recovery of tetragonal phase in infrastructures of dental prostheses base of ZrO{sub 2} (3-Y{sub 2}O{sub 3}) mills in CAD / CAM systems or panthories; Protocolo de tratamentos termicos visando recuperacao da fase tetragonal em infraestruturas de proteses dentarias a base de ZrO{sub 2}(3-Y{sub 2}O{sub 3}) fresadas em sistemas CAD/CAM ou pantografos

    Energy Technology Data Exchange (ETDEWEB)

    Simba, B.G.; Ferreira, B.; Santos, C. [Universidade de Sao Paulo (EEL/USP), Lorena, SP (Brazil). Escola de Engenharia; Costa, L. [Centro Universitario de Volta Redonda (MeMAT/UNIFOA), RJ (Brazil). Pro-Reitoria de Pesquisa e Extensao; Sa, L.F.C. de, E-mail: brgalvao@yahoo.com.br [PROTMAT Materiais Avancados, Volta Redonda, RJ (Brazil)

    2011-07-01

    ZrO{sub 2}(3%Y{sub 2}O{sub 3}) bioceramics are used as dental materials mainly as prosthesis components, because present high mechanical properties and translucence. The use of CAD/CAM machining technique needs final grinding which promotes tetragonal monoclinic transformation reducing the reliability of this ceramic. In this work, ZrO{sub 2}(3%Y{sub 2}O{sub 3}) ceramics were sintered at 1450-0h, 1530-2h or 1600-4h and characterized. Different heat-treatment (400-1200 deg C) are proposed aiming the recuperation of the tetragonal crystalline phase. (author)

  17. Testing the permeability and corrosion resistance of micro-mechanically interlocked joints

    DEFF Research Database (Denmark)

    Byskov-Nielsen, Jeppe; Holm, Allan Hjarbæk; Højsholt, Rune

    2011-01-01

    Micro-mechanical interlocking (MMI) can be applied to create new and interesting composite materials. We have employed laser structuring to achieve MMI between stainless steel and plastic with extremely high joint strength. However, the water permeability and corrosion resistance of the joint must...... be taken in order not to degrade the corrosion resistance of the sample to an unacceptable level....... is conducted. The permeability seems to be consistent with the Hagen–Poiseuille equation independent of the laser structuring technique and is orders of magnitudes larger than the diffusion rate through the plastic. Two different types of corrosion tests have been undertaken, and we show that care must...

  18. Facile route to an all-organic, triply threaded, interlocked structure by templated dynamic clipping.

    Science.gov (United States)

    Pun, Andrew; Hanifi, David A; Kiel, Gavin; O'Brien, Evan; Liu, Yi

    2012-12-21

    Encaged! Three-terminal interlocked molecular species were obtained by dynamic (2+3) assembly of a cagelike macro-bicycle around a trifurcated trispyridinium π guest. The complex is stabilized by π-π interactions and multiple [C-H⋅⋅⋅O] and [C-H⋅⋅⋅N] interactions. Uncomplexed guest molecules cocrystallize alongside the threaded complexes in the solid state, thus giving extended π-stacked columns. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Ground-state kinetics of bistable redox-active donor-acceptor mechanically interlocked molecules.

    Science.gov (United States)

    Fahrenbach, Albert C; Bruns, Carson J; Li, Hao; Trabolsi, Ali; Coskun, Ali; Stoddart, J Fraser

    2014-02-18

    The ability to design and confer control over the kinetics of theprocesses involved in the mechanisms of artificial molecular machines is at the heart of the challenge to create ones that can carry out useful work on their environment, just as Nature is wont to do. As one of the more promising forerunners of prototypical artificial molecular machines, chemists have developed bistable redox-active donor-acceptor mechanically interlocked molecules (MIMs) over the past couple of decades. These bistable MIMs generally come in the form of [2]rotaxanes, molecular compounds that constitute a ring mechanically interlocked around a dumbbell-shaped component, or [2]catenanes, which are composed of two mechanically interlocked rings. As a result of their interlocked nature, bistable MIMs possess the inherent propensity to express controllable intramolecular, large-amplitude, and reversible motions in response to redox stimuli. In this Account, we rationalize the kinetic behavior in the ground state for a large assortment of these types of bistable MIMs, including both rotaxanes and catenanes. These structures have proven useful in a variety of applications ranging from drug delivery to molecular electronic devices. These bistable donor-acceptor MIMs can switch between two different isomeric states. The favored isomer, known as the ground-state co-conformation (GSCC) is in equilibrium with the less favored metastable state co-conformation (MSCC). The forward (kf) and backward (kb) rate constants associated with this ground-state equilibrium are intimately connected to each other through the ground-state distribution constant, KGS. Knowing the rate constants that govern the kinetics and bring about the equilibration between the MSCC and GSCC, allows researchers to understand the operation of these bistable MIMs in a device setting and apply them toward the construction of artificial molecular machines. The three biggest influences on the ground-state rate constants arise from

  20. Buying intoformalization? State institutions and interlocked markets in African small-scale gold mining

    DEFF Research Database (Denmark)

    Fold, Niels; Jønsson, Jesper Bosse; Yankson, Paul

    2014-01-01

    During recent decades, artisanal and small-scale mining (ASM) in Africa has increased tremendously. An unknown but significant part is constituted by activities that are not based on legally registered mining licenses. The division of formal and informal ASM is, however, dissolved in the marketing....... This paper argues that future research and design of policy mechanisms needs to focus on the inter-linkages of actors and material flows within the complex intertwinement of the formal and informal ASM sectors. Our point of departure is the findings on interlocked markets within the literature on rural...

  1. Marginal adaptation of CAD-CAM onlays: Influence of preparation design and impression technique.

    Science.gov (United States)

    Lima, Fernanda Ferruzzi; Neto, Constantino Fernandes; Rubo, José H; Santos, Gildo Coelho; Moraes Coelho Santos, Maria Jacinta

    2018-03-15

    Factors that may affect the marginal adaptation of computer-aided design and computer-aided manufacturing (CAD-CAM) restorations include preparation design, impression technique, and CAD-CAM system. The influence of impression technique and preparation design on CAD-CAM partial coverage restorations has not been fully addressed. The purpose of this in vitro study was to investigate the influence of direct and indirect digital impression techniques and 2 preparation designs on the marginal adaptation of CAD-CAM onlays. Two mesio-occlusal buccal onlay preparations with reduction of the mesiobuccal cusp were made: conventional preparation (CP) with a 1.2-mm modified shoulder margin and modified preparation (MP) flat cuspal reduction without shoulder. Virtual models were generated from each preparation by using a digital scanner (BlueCam; Dentsply Sirona) from the plastic teeth (direct digital impression) or from the stone dies (indirect digital impression). Onlays were designed using a CAD-CAM system (CEREC 4.0; Dentsply Sirona), and nanoceramic resin blocks (Lava Ultimate Restorative; 3M ESPE) were milled using the CEREC MCX milling machine. Marginal discrepancy was evaluated using an optical stereomicroscope at ×25 magnification in 18 locations distributed along the margins of the preparation. The data were analyzed by using 3-way ANOVA followed by the Tukey HSD test (α=.05). CP presented a statistically significant reduced average marginal adaptation (59 ±50 μm) than did MP (69 ±58 μm) (P<.001). The Tukey HSD test showed the presence of a significantly larger marginal discrepancy in the mesial and buccal locations of MP when compared with CP. Regarding impression techniques, the buccal location presented the smallest average marginal discrepancy in restorations fabricated with indirect impression when compared with direct impression (42 ±33 μm and 60 ±39 μm) (P<.001). The results showed that conventional preparation with a modified shoulder margin

  2. The laser Megajoule facility personnel security and safety interlocks

    International Nuclear Information System (INIS)

    Chapuis, J.C.; Arnoul, J.P.; Hurst, A.; Manson, M.

    2012-01-01

    The LMJ (Laser Megajoule) is designed to deliver about 1.4 MJ of 0.35 μm light to targets for high energy density physics experiments. Such an installation entails specific hazards related to the presence of intense laser beams, and high voltage power laser amplifiers. Furthermore, the thermonuclear fusion reactions induced by the experiment also produce different radiations and neutrons burst, and also activate various materials in the chamber environment. All these hazards could be lethal. The SSP (Personnel Safety System) was designed to prevent accidents and protect personnel working in the LMJ. To satisfy at the lowest cost the requirements of safety regulations and those of the operation management, the choice was made to implement a functional architecture built around two independent technological barriers when required by the risk level. Each technical barrier is composed of two subsets, one dedicated to hazard sources management, and the other one dedicated to worker presence management. The two completely independent barriers, even at the sensor or actuator level, are designed with different technologies adapted to the required Safety Integrity Level. The combination of these 2 barriers is equivalent to a unique barrier with a rate of dangerous failure of about 10 -6 per year

  3. Resin-composite blocks for dental CAD/CAM applications.

    Science.gov (United States)

    Ruse, N D; Sadoun, M J

    2014-12-01

    Advances in digital impression technology and manufacturing processes have led to a dramatic paradigm shift in dentistry and to the widespread use of computer-aided design/computer-aided manufacturing (CAD/CAM) in the fabrication of indirect dental restorations. Research and development in materials suitable for CAD/CAM applications are currently the most active field in dental materials. Two classes of materials are used in the production of CAD/CAM restorations: glass-ceramics/ceramics and resin composites. While glass-ceramics/ceramics have overall superior mechanical and esthetic properties, resin-composite materials may offer significant advantages related to their machinability and intra-oral reparability. This review summarizes recent developments in resin-composite materials for CAD/CAM applications, focusing on both commercial and experimental materials. © International & American Associations for Dental Research.

  4. Surgical hip dislocation for treatment of cam femoroacetabular impingement

    Directory of Open Access Journals (Sweden)

    Milind M Chaudhary

    2015-01-01

    Conclusion: Cam femoroacetabular Impingement causing pain and limitation of hip movements was treated by open osteochondroplasty after surgical hip dislocation. This reduced pain, improved hip motion and gave good to excellent results in the short term.

  5. Finding the Evidence in CAM: a Student's Perspective

    Directory of Open Access Journals (Sweden)

    Jeffrey Ghassemi

    2005-01-01

    Full Text Available This commentary offers a future health care provider's perspective on the role of complementary and alternative medicine (CAM in Western (namely, in US medical education and practice. As a student of both public health and medicine in the United States, Jeffrey Ghassemi is interested in CAM's contribution to improving medical practice and teaching. The commentary highlights the ambiguous definitions of CAM to Westerners despite the rising popularity of and expenditures for alternative modalities of care. It then argues for collaboration between alternative and established medical communities to ascertain the scientific merits of CAM. It concludes by calling for a new medical paradigm that embraces the philosophies of both communities to advance education and patient care.

  6. The Layer of Kevlar Angle-interlock Woven Fabric Effect on the Tensile Properties of Composite Materials

    Science.gov (United States)

    Xie, Wan-Chen; Guo, Xu-Yi; Yan, Tao; Zhang, Shang-Yong

    2017-09-01

    This article is based on the structure of three-dimensional angle-interlock longitudinal.The 3-layer, 5-layer, 7-layer and 9-layer of angle-interlock 3D fabrics are woven on sample weaving machine respectively with the 1500D Kevlar fiber twist filament produced by United States DuPont. At the same time, Kevlar plain weave fabric is woven, and three, five, seven and nine layers’ fabric are to be compared. In the process of VARTM composite technology, epoxy resin is matrix material, acetone is diluent, triethylene tetramine is curing agent and the five different fabrics are the reinforced materials respectively. Finally, eight different three-dimensional woven fabric composites were prepared. In this paper, the tensile properties of eight kinds of three-dimensional woven fabric composites were tested respectively.Finally, it is concluded that the five-layer angle-interlock woven fabric prepared by Kevlar fiber shows the best tensile property.

  7. Comparison of plantar pressure distribution in CAD-CAM and prefabricated foot orthoses in patients with flexible flatfeet.

    Science.gov (United States)

    Khodaei, Banafsheh; Saeedi, Hassan; Jalali, Maryam; Farzadi, Maede; Norouzi, Ehsan

    2017-12-01

    The effect of foot orthoses on plantar pressure distribution has been proven by researchers but there are some controversies about advantages of custom-made foot orthoses to less expensive prefabricated foot orthoses. Nineteen flatfeet adults between 18 and 45 participated in this study. CAD-CAM foot orthoses were made for these patients according to their foot scan. Prefabricated foot orthoses were prepared according to their foot size. Plantar pressure, force and contact area were measured using pedar ® -x in-shoe system wearing shoe alone, wearing CAD-CAM foot orthoses and wearing prefabricated foot orthoses. Repeated measures ANOVA model with post-hoc, Bonferroni comparison were used to test differences. CAD-CAM and prefabricated foot orthoses both decreased pressure and force under 2nd, 3-5 metatarsal and heel regions comparing to shoe alone condition. CAD-CAM foot orthosis increased pressure under lateral toe region in comparison to shoe alone and prefabricated foot orthosis. Both foot orthoses increased pressure and contact area in medial midfoot region comparing to shoe alone condition. Increased forces were seen at hallux and lateral toes by prefabricated foot orthoses in comparison with CAD-CAM foot orthoses and control condition, respectively. According to the results, both foot orthoses could decrease the pressure under heel and metatarsal area. It seems that the special design of CAD-CAM foot orthoses could not make great differences in plantar pressure distribution in this sample. Further research is required to determine whether these results are associated with different scan systems or design software. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Changes in microgaps, micromotion, and trabecular strain from interlocked cement-trabecular bone interfaces in total knee replacements with in vivo service

    NARCIS (Netherlands)

    Miller, M.A.; Goodheart, J.R.; Khechen, B.; Janssen, D.W.; Mann, K.A.

    2016-01-01

    The initial fixation of cemented Total Knee Replacements (TKRs) relies on mechanical interlock between cement and bone, but loss of interlock occurs with in vivo service. In this study, cement-trabeculae gap morphology and micromechanics were measured for lab prepared (representing post-operative

  9. MJO Structure in the Superparameterized CAM

    Science.gov (United States)

    Benedict, J. J.; Randall, D. A.

    2008-12-01

    The Multi-scale Modeling Framework (MMF) has recently emerged as a unique approach toward bridging the gap between conventional global climate models (GCMs) and high-resolution global cloud-resolving models. The MMF replaces conventional cloud parameterizations with a small-domain cloud-resolving model (CRM; often called in this context a "super-parameterization"), embedded within each GCM grid column, to explicitly represent clouds and their effects. Recently, the Colorado State University MMF was used to conduct a 19- year Atmospheric Model Intercomparison Project (AMIP)-style simulation using observed SSTs and sea ice extent as the lower boundary conditions and the NCAR Community Atmosphere Model (CAM) as the host GCM. Highlights from a detailed examination of the MMF-simulated structure of intraseasonal convectively- coupled disturbances, i.e., the Madden-Julian Oscillation (MJO), will be presented. In the MMF simulation, the composite structure of MJO-like disturbances compares very favorably with the observed MJO based on reanalyses and satellite-derived measurements, although the magnitude of intraseasonal variability is slightly too strong in the model.

  10. Modeling the corrosion of high-level waste containers: CAM-CRM interface

    International Nuclear Information System (INIS)

    Farmer, J.C.; Bedrossian, P.J.; McCright, R.D.

    1998-06-01

    A key component of the Engineered Barrier System (EBS) being designed for containment of spent-fuel and high-level waste at the proposed geological respository at Yucca Mountain, Nevada is a two-layer canister. In this particular design, the inner barrier is made of a corrosion resistant material (CRM) such as Alloy 825, 625 or C-22, while the outer barrier is made of a corrosion-allowance material (CAM) such as A516 or Monel 400. At the present time, Alloy C-22 and A516 are favored. This publication addresses the development of models to account for corrosion of Alloy C-22 surfaces exposed directly to the Near Field Environmental (NFE), as well as to the exacerbated conditions in the CAM-CRM crevice

  11. Cultural competency, autonomy, and spiritual conflicts related to Reiki/CAM therapies: Should patients be informed?

    Science.gov (United States)

    Arvonio, Maria Marra

    2014-01-01

    The use of complementary and alternative medicines (CAM) such as Reiki is on the rise in healthcare centers. Reiki is associated with a spirituality that conflicts with some belief systems. Catholic healthcare facilities are restricted from offering this therapy because it conflicts with the teachings of the Catholic Church. However, hospitals are offering it without disclosing the spiritual aspects of it to patients. This article will address the ethical concerns and possible legal implications associated with the present process of offering Reiki. It will address these concerns based on the Joint Commission's Standard of Cultural Competency and the ethical principles of autonomy and informed consent. A proposal will also be introduced identifying specific information which Reiki/CAM practitioners should offer to their patients out of respect of their autonomy as well as their cultural, spiritual, and religious beliefs. PMID:24899738

  12. PhenoCam Dataset v1.0: Digital Camera Imagery from the PhenoCam Network, 2000-2015

    Data.gov (United States)

    National Aeronautics and Space Administration — This dataset provides a time series of visible-wavelength digital camera imagery collected through the PhenoCam Network at each of 133 sites in North America and...

  13. Periareolar augmentation mastopexy with interlocking gore-tex suture, retrospective review of 50 consecutive patients.

    Science.gov (United States)

    Franco, Johnny; Kelly, Emma; Kelly, Michael

    2014-11-01

    Periareolar Augmentation Mastopexy is one of the most challenging operations in plastic surgery. Problems with scar quality, areolar widening, and distortion are frequent problems that interfere with a predictable result. A retrospective review was performed on fifty consecutive patients who underwent a periareolar augmentation mastopexy with the interlocking approach. Of the 50 patients, 30 had both preoperative and postoperative photographs and were the basis of the study. The age of the patients ranged from 19 to 56 years with the average age being 39 years. The postoperative follow-up averaged 9.5 months and the implants averaged 316 mL. There were no deaths, pulmonary embolism, deep vein thrombosis, or infected implants. Four patients had complications following surgery for an overall complication rate of 13%. Two patients developed an infected Gore-Tex suture. Two of these complications were treated with revision surgery. Five patients required reoperation for an overall reoperative rate of 16% (one patient was converted to a full mastopexy). As a result of this retrospective study, we have found the interlocking approach to periareolar augmentation/mastopexy to be a safe and reliable operation.

  14. Periareolar Augmentation Mastopexy with Interlocking Gore-Tex Suture, Retrospective Review of 50 Consecutive Patients

    Directory of Open Access Journals (Sweden)

    Johnny Franco

    2014-11-01

    Full Text Available BackgroundPeriareolar Augmentation Mastopexy is one of the most challenging operations in plastic surgery. Problems with scar quality, areolar widening, and distortion are frequent problems that interfere with a predictable result.MethodsA retrospective review was performed on fifty consecutive patients who underwent a periareolar augmentation mastopexy with the interlocking approach. Of the 50 patients, 30 had both preoperative and postoperative photographs and were the basis of the study.ResultsThe age of the patients ranged from 19 to 56 years with the average age being 39 years. The postoperative follow-up averaged 9.5 months and the implants averaged 316 mL. There were no deaths, pulmonary embolism, deep vein thrombosis, or infected implants. Four patients had complications following surgery for an overall complication rate of 13%. Two patients developed an infected Gore-Tex suture. Two of these complications were treated with revision surgery. Five patients required reoperation for an overall reoperative rate of 16% (one patient was converted to a full mastopexy.ConclusionsAs a result of this retrospective study, we have found the interlocking approach to periareolar augmentation/mastopexy to be a safe and reliable operation.

  15. Patología de pavimentos articulados Pathology of interlocking pavements

    Directory of Open Access Journals (Sweden)

    Carlos Hernando Higuera Sandoval

    2010-07-01

    Full Text Available Este artículo presenta los resultados de un proyecto de grado sobre patología de pavimentos articulados, el cual fue elaborado con el propósito de hacer una recolección de los deterioros típicos de los pavimentos articulados construidos con adoquines de concreto o de ladrillo; y de esta forma, elaborar un catálogo de deterioros para este tipo de estructuras que facilitará la identificación y cuantificación de los deterioros en una inspección visual. El segundo propósito de este proyecto, es la formulación para Colombia de una metodología que permita determinar el Índice de Condición de las estructuras de pavimentos articulados.This article presents the results of a thesis on pathology of interlocking pavements, which objective was to make a compilation of typical damages of interlocking pavements constructed with concrete or brick pavers and, in this way, to elaborate a catalogue of damages for this kind of structures which will make the identification and quantification of deteriorations possible in a visual inspection. The second purpose of this project is the formulation of a methodology which allows determining the Index of pavement conditions for Colombia.

  16. On the modeling and characterization of an interlocked flexible electronic skin

    Science.gov (United States)

    Khalili, Nazanin; Shen, Xuechen; Naguib, Hani E.

    2017-04-01

    Development of an electronic skin with ultra-high pressure sensitivity is now of critical importance due its broad range of applications including prosthetic skins and biomimetic robotics. Microstructured conductive composite elastomers can acquire mechanical and electrical properties analogous to those of natural skin. One of the most prominent features of human skin is its tactile sensing property which can be mimicked in an electronic skin. Herein, an electrically conductive composite comprising polydimethylsiloxane and conductive fillers is used as a flexible and stretchable piezoresistive sensor. The electrical conductivity is induced within the elastomer matrix via carbon nanotubes whereas the piezoresistivity is obtained by means of microstructuring the surface of the substrate. An interlocked array of pyramids in micro-scale allows the change in the contact resistance between two thin layers of the composite upon application of an external load. Deformation of the interlocked arrays endows the sensor with an ultra-high sensitivity to the external pressures within the range of human skin perception. Moreover, using finite element analysis, the change in the contact are between the two layers was captured for different geometries. The structure of the sensor can be optimized through an optimization model in order to acquire maximum sensitivity.

  17. Hierarchical Porous Interlocked Polymeric Microcapsules: Sulfonic Acid Functionalization as Acid Catalysts

    Science.gov (United States)

    Wang, Xiaomei; Gu, Jinyan; Tian, Lei; Zhang, Xu

    2017-03-01

    Owing to their unique structural and surface properties, mesoporous microspheres are widely applied in the catalytic field. Generally, increasing the surface area of the specific active phase of the catalyst is a good method, which can achieve a higher catalytic activity through the fabrication of the corresponding catalytic microspheres with the smaller size and hollow structure. However, one of the major challenges in the use of hollow microspheres (microcapsules) as catalysts is their chemical and structural stability. Herein, the grape-like hypercrosslinked polystyrene hierarchical porous interlocked microcapsule (HPIM-HCL-PS) is fabricated by SiO2 colloidal crystals templates, whose structure is the combination of open mouthed structure, mesoporous nanostructure and interlocked architecture. Numerous microcapsules assembling together and forming the roughly grape-like microcapsule aggregates can enhance the structural stability and recyclability of these microcapsules. After undergoing the sulfonation, the sulfonated HPIM-HCL-PS is served as recyclable acid catalyst for condensation reaction between benzaldehyde and ethylene glycol (TOF = 793 h-1), moreover, exhibits superior activity, selectivity and recyclability.

  18. Bacterial carbonate precipitation improves water absorption of interlocking compressed earth block (ICEB)

    Science.gov (United States)

    Zamer, M. M.; Irwan, J. M.; Othman, N.; Faisal, S. K.; Anneza, L. H.; Alshalif, A. F.; Teddy, T.

    2017-11-01

    Interlocking compressed earth blocks (ICEB) are soil based blocks that allows for mortarless construction. The addition of many alternative materials into interlocking block in order to improve the durability has been reported. However there are currently lack of report and evidence on the application of biocalcification or microbiologically induced calcite precipitation (MICP) in improving the engineering properties of ICEB. This paper evaluate the effect of UB in improving the water absorption properties of ICEB. This paper also provide the results on SEM analysis of addition of 1%, 3% and 5% UB in ICEB. The bacteria were added as partial replacement of limestone water in ICEB. The results showed the reduction of 14.72% with 5% UB on initial water absorption followed by the results for water absorption by 24-hour soaking which also indicates reduction of 14.68% with 5% UB on 28th days of testing compared to control specimen. It was expected that the reduction of water absorption was due to the plugging of pores by the bacterial calcite which prevent ingression of water in ICEB samples. Therefore this study hopes that the positive results from the UB as improving in water absorption of ICEB will lead to improve others ICEB properties and others construction materials.

  19. Treatment of acute fractures of the femoral shaft with reamed intramedullary interlocking AO nails.

    Science.gov (United States)

    Umer, M; Niazi, A K; Hussain, D; Ahmad, M

    2004-08-01

    To review and audit our experience with closed intramedullary interlocking nailing for acute femoral shaft fractures. All patients admitted to The Aga Khan University Hospital, over the last six years and with a minimum follow-up of twelve months, with acute fractures of the femoral shaft were included in the study. All patients treated for established non-unions and infections or with pathological fractures were excluded from the study. There were 89 fractures, 74% of whom were closed and 50% were associated with other orthopedic injuries. Most of these were younger patients involved in high velocity road traffic accidents. The union rate was 88% with 4.4% of fractures going into non-union. The remaining 8% of the fractures went into a phase of delayed union, but ultimately united, making the overall success rate to be 95.6%. The mean time for union was 11.5 weeks. At the final clinical follow-up, 4% of the patients had minor pain, 7% had limp, 4% had leg length discrepancy of more than 2 cm and 4% had decreased range of motion at the hip or knee joints. We had a 4% rate of superficial infection. There were 3 cases of pudendal nerve neuropraxia and 2 cases of deep vein thrombosis. Intramedullary Interlocking nailing is a safe and effective treatment modality for acute fractures of the femoral shaft. Proper surgical decision making regarding static versus dynamic mode of locking can avoid problems of delayed union.

  20. Abating coal tar seepage into surface water bodies using sheet piles with sealed interlocks

    International Nuclear Information System (INIS)

    Collingwood, B.I.; Boscardin, M.D.; Murdock, R.F.

    1995-01-01

    A former coal tar processing facility processed crude coal tar supplied from manufactured gas plants in the area. Coal-tar-contaminated ground water from the site was observed seeping through an existing timber bulkhead along a tidal river and producing a multicolored sheen on the surface of the river. As part of a short-term measure to abate the seepage into the river, 64-m long anchored sheet pile wall with sheet pile wing walls at each end was constructed inland of the of the timber bulkhead. The sheet piles extended to low-permeability soils at depth and the interlocks of the sheet piles were provided with polyurethane rubber seals. Based on postconstruction observations for leakage and sheens related to leakage, the steel sheet piles with polyurethane rubber interlock seals appeared to provide a successful seal and abate coal-tar-contaminated ground water seepage into the river. The tie rod penetration sealing proved to be a more problematic detail, but through several postconstruction grouting episodes, an effective seal was produced

  1. Effect of microtrichia on the interlocking mechanism in the Asian ladybeetle, Harmonia axyridis (Coleoptera: Coccinellidae).

    Science.gov (United States)

    Sun, Jiyu; Liu, Chao; Bhushan, Bharat; Wu, Wei; Tong, Jin

    2018-01-01

    The hindwings of beetles are folded under the elytra when they are at rest but are extended during flight, which can provide bioinspiration for the design of deployable micro air vehicles (MAVs). Beetle hindwings must be able to be both securely locked under the elytra and freely extended for flight, depending on the required action. To investigate the locking mechanism, this study used environmental scanning electron microscopy (ESEM) to examine the microstructures of the elytra, hindwings and abdomen of the Asian ladybeetle, Harmonia axyridis (Pallas, 1773). On the ventral side (VS) of the elytra, the microtrichia show a transitional structure from the lateral edge to the medial edge. On the hindwing surface, the folded regions were observed on both the dorsal side (DS) and the VS. On the abdomen, the microtrichia between the abdominal segments show a cyclical change from sparse to dense in each segment in the middle of the abdomen. Furthermore, the different directions of microtrichia that lead to self-locking friction on the surfaces of the hindwing, elytron and abdomen appear to facilitate interlocking. A model for the interlocking of the hindwings of the H. axyridis was established, and its underlying mechanism is discussed.

  2. A CNES remote operations center for the MSL ChemCam instrument

    Energy Technology Data Exchange (ETDEWEB)

    Wiens, Roger C [Los Alamos National Laboratory; Lafaille, Vivian [CNES; Lorgny, Eric [CNES; Baroukh, Julien [CNES; Gaboriaud, Alain [CNES; Saccoccio, Muriel [CNES; Perez, Rene [CNES; Gasnault, Olivier [CNRS/CESR; Maurice, Sylvestre [CNRS/CESR; Blaney, Diana [JPL

    2010-01-01

    For the first time, a CNES remote operations center in Toulouse will be involved in the tactical operations of a Martian rover in order to operate the ChemCam science instrument in the framework of the NASA MSL (Mars Science Laboratory) mission in 2012. CNES/CESR and LANL have developed and delivered to JPL the ChemCam (Chemistry Camera) instrument located on the top of mast and in the body of the rover. This instrument incorporates a Laser-Induced Breakdown Spectrometer (LIBS) and a Remote Micro-Imager (RMI) for determining elemental compositions of rock targets or soil samples at remote distances from the rover (2-7 m). An agreement has been achieved for operating ChemCam, alternatively, from Toulouse (FR) and Los Alamos (NM, USA), through the JPL ground data system in Pasadena (CA, USA) for a complete Martian year (2 years on Earth). After a brief overview of the MSL mission, this paper presents the instrument, the mission operational system and JPL organization requirements for the scientific investigators (PI and Co-Is). This paper emphasizes innovations applied on the ground segment components and on the operational approach to satisfy the requirements and constraints due to these shared and distributed operations over the world.

  3. An analytical hierarchical model explaining the robustness and flaw-tolerance of the interlocking barb-barbule structure of bird feathers

    Science.gov (United States)

    Chen, Qiang; Gorb, Stanislav; Kovalev, Alexander; Li, Zhiyong; Pugno, Nicola

    2016-10-01

    Feathers can fulfill their aerodynamic function only if the pennaceous vane forms an airfoil stabilized by robust interlocking between barbules. Thus, revealing the robustness of the interlocking mechanical behavior of the barbules is very important to understand the function and long-term resilience of bird feathers. This paper, basing on the small- and large-beam deflection solutions, presents a hierarchical mechanical model for deriving the critical delamination conditions of the interlocking barbules between two adjacent barbs in bird feathers. The results indicate a high robustness and flaw-tolerant design of the structure. This work contributes to the understanding of the mechanical behavior of the robust interlocking barb-barbule structure of the bird feather, and provides a basis for design of feather-inspired materials with robust interlocking mechanism, such as advanced bio-inspired micro-zipping devices.

  4. Two Years on: Koha 3.0 in Use at the CAMLIS Library, Royal London Homoeopathic Hospital

    Science.gov (United States)

    Bissels, Gerhard; Chandler, Andrea

    2010-01-01

    Purpose: The purpose of this paper is to describe the further development of the Koha 3.0 library management system (LMS) and the involvement of external software consultants at the Complementary and Alternative Medicine Library and Information Service (CAMLIS), Royal London Homoeopathic Hospital. Design/methodology/approach: The paper takes the…

  5. B[e] Star CI Cam: Eighteen Years of Research

    Science.gov (United States)

    Goranskij, V. P.; Barsukova, E. A.; Bjorkman, K. S.; Burenkov, A. N.; Klochkova, V. G.; Manset, N.; Metlova, N. V.; Miroshnichenko, A. S.; Panchuk, V. E.; Yushkin, M. V.; Zharikov, S. V.

    2017-02-01

    We present the results of extensive spectroscopic and photometric observations of CI Cam performed after its outburst in April 1998. The outburst was interpreted as a thermonuclear runaway of hydrogen on the surface of a white dwarf (WD). We detected variations of both the brightness and the He II 4686 Å line radial velocity with a period of 19d.400±0d.015 due to orbital motion of the WD. The rapid brightness variations on a timescale of hours is explained by pulsations of a B4 III-V[e] star. In 2012, the system entered an active state with the stronger He II line and with the brightness increased by 0.4 mag. We observed a slow low-amplitude drift in the velocity of Fe II and [N II] emission lines which we explained by the orbital motion of the B[e] star + WD system along with all its gaseous environment around a third companion invisible in the spectra. The active phase of the B[e] star might have been initiated by a close approach of the binary and the third companion in 2007.

  6. Microleakage of composite crowns luted on CAD/CAM-milled human molars: a new method for standardized in vitro tests.

    Science.gov (United States)

    Schlenz, Maximiliane Amelie; Schmidt, Alexander; Rehmann, Peter; Niem, Thomas; Wöstmann, Bernd

    2018-04-24

    To investigate debonding of full crowns made of CAD/CAM composites, CAD/CAM technology was applied to manufacture standardized test abutments to increase the reproducibility of human teeth used in in vitro studies. A virtual test abutment and the corresponding virtual crown were designed and two STL data sets were generated. Sixty-four human third molars and CAD/CAM blocks were milled using a CNC machine. Crowns of four different composite blocks (Lava Ultimate (LU), Brilliant Crios (BC), Cerasmart (CS), Experimental (EX)) were adhesively bonded with their corresponding luting system (LU: Scotchbond Universal/RelyX Ultimate; BC: One Coat 7 Universal/DuoCem; CS: G-PremioBond/G-Cem LinkForce; EX: Experimental-Bond/Experimental-Luting-Cement). Half of the specimens were chemical-cured (CC) and the others were light-cured (LC). Afterwards, specimens were artificially aged in a chewing simulator (WL-tec, 1 million cycles, 50-500 N, 2 Hz, 37 °C). Finally, a dye penetration test was used to detect debonding. For inspection, the specimens were sliced, and penetration depth was measured with a digital microscope. Data were analyzed with the Mann-Whitney U test. No cases of total debonding were observed after cyclic loading. However, the LC specimens showed a significantly lower amount of leakage than the CC ones (p CAD/CAM technology in highly standardized test abutments for in vitro testing. For CAD/CAM composites, light curing should be performed. The success of a restoration depends on the long-term sealing ability of the luting materials, which avoids debonding along with microleakage. For CAD/CAM composites, separate light curing of the adhesive and luting composite is highly recommended.

  7. Examination of a high resolution laser optical plankton counter and FlowCAM for measuring plankton concentration and size

    Science.gov (United States)

    Kydd, Jocelyn; Rajakaruna, Harshana; Briski, Elizabeta; Bailey, Sarah

    2018-03-01

    Many commercial ships will soon begin to use treatment systems to manage their ballast water and reduce the global transfer of harmful aquatic organisms and pathogens in accordance with upcoming International Maritime Organization regulations. As a result, rapid and accurate automated methods will be needed to monitoring compliance of ships' ballast water. We examined two automated particle counters for monitoring organisms ≥ 50 μm in minimum dimension: a High Resolution Laser Optical Plankton Counter (HR-LOPC), and a Flow Cytometer with digital imaging Microscope (FlowCAM), in comparison to traditional (manual) microscopy considering plankton concentration, size frequency distributions and particle size measurements. The automated tools tended to underestimate particle concentration compared to standard microscopy, but gave similar results in terms of relative abundance of individual taxa. For most taxa, particle size measurements generated by FlowCAM ABD (Area Based Diameter) were more similar to microscope measurements than were those by FlowCAM ESD (Equivalent Spherical Diameter), though there was a mismatch in size estimates for some organisms between the FlowCAM ABD and microscope due to orientation and complex morphology. When a single problematic taxon is very abundant, the resulting size frequency distribution curves can become skewed, as was observed with Asterionella in this study. In particular, special consideration is needed when utilizing automated tools to analyse samples containing colonial species. Re-analysis of the size frequency distributions with the removal of Asterionella from FlowCAM and microscope data resulted in more similar curves across methods with FlowCAM ABD having the best fit compared to the microscope, although microscope concentration estimates were still significantly higher than estimates from the other methods. The results of our study indicate that both automated tools can generate frequency distributions of particles

  8. Reasons for continuing use of Complementary and Alternative Medicine (CAM) in students: a consumer commitment model.

    Science.gov (United States)

    Sirois, Fuschia M; Salamonsen, Anita; Kristoffersen, Agnete E

    2016-02-24

    Research on continued CAM use has been largely atheoretical and has not considered the broader range of psychological and behavioral factors that may be involved. The purpose of this study was to test a new conceptual model of commitment to CAM use that implicates utilitarian (trust in CAM) and symbolic (perceived fit with CAM) in psychological and behavioral dimensions of CAM commitment. A student sample of CAM consumers, (N = 159) completed a survey about their CAM use, CAM-related values, intentions for future CAM use, CAM word-of-mouth behavior, and perceptions of being an ongoing CAM consumer. Analysis revealed that the utilitarian, symbolic, and CAM commitment variables were significantly related, with r's ranging from .54 to .73. A series hierarchical regression analyses controlling for relevant demographic variables found that the utilitarian and symbolic values uniquely accounted for significant and substantial proportion of the variance in each of the three CAM commitment indicators (R(2) from .37 to .57). The findings provide preliminary support for the new model that posits that CAM commitment is a multi-dimensional psychological state with behavioral indicators. Further research with large-scale samples and longitudinal designs is warranted to understand the potential value of the new model.

  9. Color stability of CAD/CAM Zirconia ceramics following exposure to acidic and staining drinks

    Science.gov (United States)

    Colombo, Marco; Cavallo, Marco; Miegge, Matteo; Dagna, Alberto; Beltrami, Riccardo; Chiesa, Marco

    2017-01-01

    Background The aim of this in vitro study was to evaluate the color stability of CAD/CAM Zirconia ceramics following exposure to acidic drink (Coca Cola) and after exposure to staining solution (coffee). Material and Methods All the samples were immersed in different staining solutions over a 28-day test period. A colorimetric evaluation according to the CIE L*a*b* system was performed by a blind trained operator at 7, 14, 21, 28 days of the staining process. Shapiro Wilk test and Kruskal-Wallis ANOVA were applied to assess significant differences among restorative materials. Paired t-test was applied to test which CIE L*a*b* parameters significantly changed after immersion in staining solutions. Results One week immersion in acidic drink did not cause a perceivable discoloration for all restorative materials (ΔE < 3.3). Subsequent immersion in coffee affected color stability of all Zirconia samples, even if Kruskal-Wallis ANOVA found significant differences among the various restorative materials. Conclusions The ∆Es of CAD/CAM Zirconia ceramics after immersion in coffee varied among the products, but color integrity is not affected by contact with acidic drinks. Key words:CAD/CAM restorative materials, CIE Lab, Zirconia ceramics. PMID:29302281

  10. Color stability of CAD/CAM Zirconia ceramics following exposure to acidic and staining drinks.

    Science.gov (United States)

    Colombo, Marco; Cavallo, Marco; Miegge, Matteo; Dagna, Alberto; Beltrami, Riccardo; Chiesa, Marco; Poggio, Claudio

    2017-11-01

    The aim of this in vitro study was to evaluate the color stability of CAD/CAM Zirconia ceramics following exposure to acidic drink (Coca Cola) and after exposure to staining solution (coffee). All the samples were immersed in different staining solutions over a 28-day test period. A colorimetric evaluation according to the CIE L*a*b* system was performed by a blind trained operator at 7, 14, 21, 28 days of the staining process. Shapiro Wilk test and Kruskal-Wallis ANOVA were applied to assess significant differences among restorative materials. Paired t-test was applied to test which CIE L*a*b* parameters significantly changed after immersion in staining solutions. One week immersion in acidic drink did not cause a perceivable discoloration for all restorative materials (ΔE < 3.3). Subsequent immersion in coffee affected color stability of all Zirconia samples, even if Kruskal-Wallis ANOVA found significant differences among the various restorative materials. The ∆Es of CAD/CAM Zirconia ceramics after immersion in coffee varied among the products, but color integrity is not affected by contact with acidic drinks. Key words: CAD/CAM restorative materials, CIE Lab, Zirconia ceramics.

  11. Medical Ethnobotany in Europe: From Field Ethnography to a More Culturally Sensitive Evidence-Based CAM?

    Science.gov (United States)

    Quave, Cassandra L.; Pardo-de-Santayana, Manuel; Pieroni, Andrea

    2012-01-01

    European folk medicine has a long and vibrant history, enriched with the various documented uses of local and imported plants and plant products that are often unique to specific cultures or environments. In this paper, we consider the medicoethnobotanical field studies conducted in Europe over the past two decades. We contend that these studies represent an important foundation for understanding local small-scale uses of CAM natural products and allow us to assess the potential for expansion of these into the global market. Moreover, we discuss how field studies of this nature can provide useful information to the allopathic medical community as they seek to reconcile existing and emerging CAM therapies with conventional biomedicine. This is of great importance not only for phytopharmacovigilance and managing risk of herb-drug interactions in mainstream patients that use CAM, but also for educating the medical community about ethnomedical systems and practices so that they can better serve growing migrant populations. Across Europe, the general status of this traditional medical knowledge is at risk due to acculturation trends and the urgency to document and conserve this knowledge is evident in the majority of the studies reviewed. PMID:22899952

  12. Objective Tuning of Model Parameters in CAM5 Across Different Spatial Resolutions

    Science.gov (United States)

    Bulaevskaya, V.; Lucas, D. D.

    2014-12-01

    Parameterizations of physical processes in climate models are highly dependent on the spatial and temporal resolution and must be tuned for each resolution under consideration. At high spatial resolutions, objective methods for parameter tuning are computationally prohibitive. Our work has focused on calibrating parameters in the Community Atmosphere Model 5 (CAM5) for three spatial resolutions: 1, 2, and 4 degrees. Using perturbed-parameter ensembles and uncertainty quantification methodology, we have identified input parameters that minimize discrepancies of energy fluxes simulated by CAM5 across the three resolutions and with respect to satellite observations. We are also beginning to exploit the parameter-resolution relationships to objectively tune parameters in a high-resolution version of CAM5 by leveraging cheaper, low-resolution simulations and statistical models. We will present our approach to multi-resolution climate model parameter tuning, as well as the key findings. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under contract DE-AC52-07NA27344 and was supported from the DOE Office of Science through the Scientific Discovery Through Advanced Computing (SciDAC) project on Multiscale Methods for Accurate, Efficient, and Scale-Aware Models of the Earth System.

  13. Novel Diagnosis of Lyme Disease: Potential for CAM Intervention

    Directory of Open Access Journals (Sweden)

    Aristo Vojdani

    2009-01-01

    Full Text Available Lyme disease (LD is the most common tick-borne disease in the northern hemisphere, producing a wide range of disabling effects on multiple human targets, including the skin, the nervous system, the joints and the heart. Insufficient clinical diagnostic methods, the necessity for prompt antibiotic treatment along with the pervasive nature of infection impel the development and establishment of new clinical diagnostic tools with increased accuracy, sensitivity and specificity. The goal of this article is 4-fold: (i to detail LD infection and pathology, (ii to review prevalent diagnostic methods, emphasizing inherent problems, (iii to introduce the usage of in vivo induced antigen technology (IVIAT in clinical diagnostics and (iv to underscore the relevance of a novel comprehensive LD diagnostic approach to practitioners of Complementary and Alternative Medicine (CAM. Utilization of this analytical method will increase the accuracy of the diagnostic process and abridge the time to treatment, with antibiotics, herbal medicines and nutritional supplements, resulting in improved quality of care and disease prognosis.

  14. Pervious Pavement System Evaluation-Poster

    Science.gov (United States)

    Pervious pavement is a low impact development stormwater control. The Environmental Protection Agency's Urban Watershed Management Branch is evaluating interlocking concrete pavingstone pervious pavement systems. The pavingstones themselves are impermeable, but the spaces between...

  15. Interlocking Toy Building Blocks as Hands-On Learning Modules for Blind and Visually Impaired Chemistry Students

    Science.gov (United States)

    Melaku, Samuel; Schreck, James O.; Griffin, Kameron; Dabke, Rajeev B.

    2016-01-01

    Interlocking toy building blocks (e.g., Lego) as chemistry learning modules for blind and visually impaired (BVI) students in high school and undergraduate introductory or general chemistry courses are presented. Building blocks were assembled on a baseplate to depict the relative changes in the periodic properties of elements. Modules depicting…

  16. The inducible CAM plants in putative lunar lander experiments

    Science.gov (United States)

    Burlak, Olexii; Zaetz, Iryna; Soldatkin, Olexii; Rogutskyy, Ivan; Danilchenko, Boris; Mikheev, Olexander; de Vera, Jean-Pierre; Vidmachenko, Anatolii; Foing, Bernard H.; Kozyrovska, Natalia

    Precursory lunar lander experiments on growing plants in locker-based chambers will increase our understanding of effect of lunar conditions on plant physiology. The inducible CAM (Cras-sulacean Acid Metabolism)-plants are reasonable model for a study of relationships between environmental challenges and changes in plant/bacteria gene expression. In inducible CAM-plants the enzymatic machinery for the environmentally activated CAM switches on from a C3-to a full-CAM mode of photosynthesis in response to any stresses (Winter et al., 2008). In our study, Kalanchoe spp. are shown to be promising candidates for putative lunar experiments as resistant to irradiation and desiccation, especially after inoculation with a bacterial consortium (Boorlak et al., 2010). Within frames of the experiment we expect to get information about the functional activity of CAM-plants, in particular, its organogenesis, photosystem, the circadian regulation of plant metabolism on the base of data gaining with instrumental indications from expression of the reporter genes fused to any genes involved in vital functions of the plant (Kozyrovska et al., 2009). References 1. Winter K., Garcia M., Holtum J. (2008) J. Exp. Bot. 59(7):1829-1840 2. Bourlak O., Lar O., Rogutskyy I., Mikheev A., Zaets I., Chervatyuk N., de Vera J.-P., Danilchenko A.B. Foing B.H., zyrovska N. (2010) Space Sci. Technol. 3. Kozyrovska N.O., Vidmachenko A.P., Foing B.H. et al. Exploration/call/estec/ESA. 2009.

  17. Validity of PALMS GPS scoring of active and passive travel compared with SenseCam.

    Science.gov (United States)

    Carlson, Jordan A; Jankowska, Marta M; Meseck, Kristin; Godbole, Suneeta; Natarajan, Loki; Raab, Fredric; Demchak, Barry; Patrick, Kevin; Kerr, Jacqueline

    2015-03-01

    The objective of this study is to assess validity of the personal activity location measurement system (PALMS) for deriving time spent walking/running, bicycling, and in vehicle, using SenseCam (Microsoft, Redmond, WA) as the comparison. Forty adult cyclists wore a Qstarz BT-Q1000XT GPS data logger (Qstarz International Co., Taipei, Taiwan) and SenseCam (camera worn around the neck capturing multiple images every minute) for a mean time of 4 d. PALMS used distance and speed between global positioning system (GPS) points to classify whether each minute was part of a trip (yes/no), and if so, the trip mode (walking/running, bicycling, or in vehicle). SenseCam images were annotated to create the same classifications (i.e., trip yes/no and mode). Contingency tables (2 × 2) and confusion matrices were calculated at the minute level for PALMS versus SenseCam classifications. Mixed-effects linear regression models estimated agreement (mean differences and intraclass correlation coefficients) between PALMS and SenseCam with regard to minutes/day in each mode. Minute-level sensitivity, specificity, and negative predictive value were ≥88%, and positive predictive value was ≥75% for non-mode-specific trip detection. Seventy-two percent to 80% of outdoor walking/running minutes, 73% of bicycling minutes, and 74%-76% of in-vehicle minutes were correctly classified by PALMS. For minutes per day, PALMS had a mean bias (i.e., amount of over or under estimation) of 2.4-3.1 min (11%-15%) for walking/running, 2.3-2.9 min (7%-9%) for bicycling, and 4.3-5 min (15%-17%) for vehicle time. Intraclass correlation coefficients were ≥0.80 for all modes. PALMS has validity for processing GPS data to objectively measure time spent walking/running, bicycling, and in vehicle in population studies. Assessing travel patterns is one of many valuable applications of GPS in physical activity research that can improve our understanding of the determinants and health outcomes of active

  18. The Community Structure of the European Network of Interlocking Directorates 2005–2010

    Science.gov (United States)

    Heemskerk, Eelke M.; Daolio, Fabio; Tomassini, Marco

    2013-01-01

    The boards of directors at large European companies overlap with each other to a sizable extent both within and across national borders. This could have important economic, political and management consequences. In this work we study in detail the topological structure of the networks that arise from this phenomenon. Using a comprehensive information database, we reconstruct the implicit networks of shared directorates among the top 300 European firms in 2005 and 2010, and suggest a number of novel ways to explore the trans-nationality of such business elite networks. Powerful community detection heuristics indicate that geography still plays an important role: there exist clear communities and they have a distinct national character. Nonetheless, from 2005 to 2010 we observe a densification of the boards interlocks network and a larger transnational orientation in its communities. Together with central actors and assortativity analyses, we provide statistical evidence that, at the level of corporate governance, Europe is getting closer. PMID:23894318

  19. Testing the permeability and corrosion resistance of micro-mechanically interlocked joints

    Science.gov (United States)

    Byskov-Nielsen, Jeppe; Holm, Allan H.; Højsholt, Rune; Sá, Pedro; Balling, Peter

    2011-09-01

    Micro-mechanical interlocking (MMI) can be applied to create new and interesting composite materials. We have employed laser structuring to achieve MMI between stainless steel and plastic with extremely high joint strength. However, the water permeability and corrosion resistance of the joint must be examined. For many industrially relevant applications it is important to keep water away from certain parts and to prevent the sample from corroding. A thorough study of the permeability of the interconnected samples at different temperatures and after employing different laser-structuring techniques is conducted. The permeability seems to be consistent with the Hagen-Poiseuille equation independent of the laser structuring technique and is orders of magnitudes larger than the diffusion rate through the plastic. Two different types of corrosion tests have been undertaken, and we show that care must be taken in order not to degrade the corrosion resistance of the sample to an unacceptable level.

  20. Reuse of mining dams waste for the processing of interlocking blocks for paving

    International Nuclear Information System (INIS)

    Machado, Raissa Ribeiro Lima; Ribeiro, Guilherme Borges; Silva, Sidney Nicodemos da

    2014-01-01

    The environmental impact of mining dam residues can be mitigated by their reuse in the production of interlocking blocks for pavements with a mechanical strength greater than 50 MPa. From the mixture of cement CPV-ARI, sand and gravel, the characterization of the mechanical and physicochemical properties was performed by the following procedures: SEM, FRX, XRD, compression tests and thermal analysis (DSC). These blocks produced from these residues can be considered an economical alternative for the mining depletion cycle in the State of Minas Gerais. This work sought to improve the traces with the replacement the sand of the rivers bed by residues of mining dams that can represent an opportunity for generation of employment and income

  1. The community structure of the European network of interlocking directorates 2005-2010.

    Science.gov (United States)

    Heemskerk, Eelke M; Daolio, Fabio; Tomassini, Marco

    2013-01-01

    The boards of directors at large European companies overlap with each other to a sizable extent both within and across national borders. This could have important economic, political and management consequences. In this work we study in detail the topological structure of the networks that arise from this phenomenon. Using a comprehensive information database, we reconstruct the implicit networks of shared directorates among the top 300 European firms in 2005 and 2010, and suggest a number of novel ways to explore the trans-nationality of such business elite networks. Powerful community detection heuristics indicate that geography still plays an important role: there exist clear communities and they have a distinct national character. Nonetheless, from 2005 to 2010 we observe a densification of the boards interlocks network and a larger transnational orientation in its communities. Together with central actors and assortativity analyses, we provide statistical evidence that, at the level of corporate governance, Europe is getting closer.

  2. Tensile Damage Mechanism of 3-D Angle-Interlock Woven Composite using Acoustic Emission Events Monitoring

    Directory of Open Access Journals (Sweden)

    Ma Qian

    2018-03-01

    Full Text Available The quasi-static tensile damage behavior of one type of layer-to-layer 3-Dimensional Angle-interlock Woven Composite (3DAWC was tested and analyzed in this paper. Incorporated with the acoustic emission (AE events monitoring, the mechanical behavior of the 3DAWC under tensile loading condition was characterized. The Load-Extension curve, Load/AE events-Time curves occurred during the entire testing process and tensile damage modes were recorded to characterize and summarize the mechanical properties and damage mechanism of the 3DAWC subjected to tensile loading. It was found that the tensile damage of the 3DAWC could be summarized into 3 steps. And each step has a distinct primary damage mode. Moreover, the resin cracks, resin-yarn interface debonding and yarn breakages were the main damage modes for the 3DAWC.

  3. Transparent superhydrophobic coating application to the interlocking clay block for the microbial growth mitigation

    Science.gov (United States)

    Nimittrakoolchai, O.; Suwan, M.; Supothina, S.

    2017-12-01

    Interlocking clay block is of widespread use in many countries due to its less labor-intensive design. The block comprises of considerable amount of pore structures; therefore water can easily penetrate into it causing deterioration by natural weathering as well as the growth of microbes on its surface. In this present work, a transparent, superhydrophobic coating was applied onto the block’s surface to prevent water absorption. The coating which is a poly(methyl hydrogensiloxane) base containing fumed SiO2 nanoparticle was designed to possess surface topographic feature similar to that of the lotus leaf. After coating the block with the superhydrophobic compound, its water absorption decreased from 11.5 to 4.8% and porosity substantially decreased from 22.5 to 9.2%, while bulk and apparent densities did not change. Accelerated weathering test revealed that the coating had good stability. The coated samples exhibited growth inhibition of algae.

  4. The community structure of the European network of interlocking directorates 2005-2010.

    Directory of Open Access Journals (Sweden)

    Eelke M Heemskerk

    Full Text Available The boards of directors at large European companies overlap with each other to a sizable extent both within and across national borders. This could have important economic, political and management consequences. In this work we study in detail the topological structure of the networks that arise from this phenomenon. Using a comprehensive information database, we reconstruct the implicit networks of shared directorates among the top 300 European firms in 2005 and 2010, and suggest a number of novel ways to explore the trans-nationality of such business elite networks. Powerful community detection heuristics indicate that geography still plays an important role: there exist clear communities and they have a distinct national character. Nonetheless, from 2005 to 2010 we observe a densification of the boards interlocks network and a larger transnational orientation in its communities. Together with central actors and assortativity analyses, we provide statistical evidence that, at the level of corporate governance, Europe is getting closer.

  5. External jig-aided intramedullary interlocking nailing of diaphyseal fractures: experience from a tropical developing centre.

    Science.gov (United States)

    Ikpeme, Ikpeme; Ngim, Ngim; Udosen, Anthony; Onuba, Obiora; Enembe, Okokon; Bello, Segun

    2011-01-01

    Intramedullary interlocking nailing for diaphyseal fractures is a standard treatment option in affluent societies. These procedures are often performed under image intensifier guidance. The cost of these gadgets precludes their common use in resource poor regions. External jig-aided intramedullary interlocking nailing is relatively cheap and offers the chance for performing these procedures in resource poor regions. The aim of this study was to document the advantages, challenges and outcome of this form of treatment in a resource poor setting. The Surgical Implant Generation Network (SIGN) implants and instrumentation were used for this study. Thirty-seven limbs in 35 patients were included. There were 30 males and five females giving a ratio of 6:1. The mean age was 35 ± 11.9 years with a range of 15-61 years. The femur and tibia were the bones studied with a total of 23 and 14 fractures, respectively (ratio 1.6:1). There were 14 comminuted fractures, two segmented fractures, six mal-unions, eight non-unions and seven simple fractures. Road traffic accidents were the most common cause of injuries with motorcycle accidents accounting for 19 (57.4%) cases. The mean follow-up period was 22 ± 5.32 months, mean time to union was 16.9 ± 5.4 weeks and the major complication was osteomyelitis (10.8%). We conclude that this is a viable treatment option for musculoskeletal injuries in resource poor regions. Education to encourage early acceptance of surgical intervention and reduced patronage of traditional bone setting for injudicious interventions can reduce the infective complication rates.

  6. Illness narratives in cancer: CAM and spiritual practices

    DEFF Research Database (Denmark)

    Ulrich, Anita; Evron, Lotte; Ostenfeld-Rosenthal, Ann

    2011-01-01

    Objectives: In this paper,we investigate Danish cancer patients’ narratives on spiritual beliefs and practices and the relationship these practices may have to complementary and alternative medicine (CAM). Design: Narrative inquiry is used to uncover how spiritual beliefs and practices may...... be related to CAM. The analysis is based on empirical findings from a recent PhD project. During a two-year period first author followed 32 cancer patients, family, friends and alternative practitioners through interviews, telephone conversations, treatments and in focus groups. Results: As a general pattern......, religious and spiritual issues were not extensively unfolded in participants’ illness narratives. However, these issues were significantly elaborated on in narratives by four female participants. Conclusion: We propose that for some cancer patients CAM may function, not only or primarily as a treatment...

  7. The impact on UT/LS cirrus clouds in the CAM/CARMA model using a new interactive aerosol parameterization.

    Science.gov (United States)

    Maloney, C.; Toon, B.; Bardeen, C.

    2017-12-01

    Recent studies indicate that heterogeneous nucleation may play a large role in cirrus cloud formation in the UT/LS, a region previously thought to be primarily dominated by homogeneous nucleation. As a result, it is beneficial to ensure that general circulation models properly represent heterogeneous nucleation in ice cloud simulations. Our work strives towards addressing this issue in the NSF/DOE Community Earth System Model's atmospheric model, CAM. More specifically we are addressing the role of heterogeneous nucleation in the coupled sectional microphysics cloud model, CARMA. Currently, our CAM/CARMA cirrus model only performs homogenous ice nucleation while ignoring heterogeneous nucleation. In our work, we couple the CAM/CARMA cirrus model with the Modal Aerosol Model (MAM). By combining the aerosol model with CAM/CARMA we can both account for heterogeneous nucleation, as well as directly link the sulfates used for homogeneous nucleation to computed fields instead of the current static field being utilized. Here we present our initial results and compare our findings to observations from the long running CALIPSO and MODIS satellite missions.

  8. CAM visual stimulation with conventional method of occlusion treatment in amblyopia: a randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Ali Reza Jafari

    2014-04-01

    Conclusion: Using of CAM visual stimulation along with conventional occlusion will further improve visual acuity and stereopsis in amblyopic children. These findings recommended the CAM visual stimulation as an accompanying and complementary method in amblyopia treatment.

  9. Special Section: Complementary and Alternative Medicine (CAM):Quiz on Complementary and Alternative Medicine

    Science.gov (United States)

    ... Special Section CAM Quiz on Complementary and Alternative Medicine Past Issues / Winter 2009 Table of Contents For ... low back pain. True False Complementary and alternative medicine (CAM) includes: Meditation Chiropractic Use of natural products, ...

  10. QuadCam - A Quadruple Polarimetric Camera for Space Situational Awareness

    Science.gov (United States)

    Skuljan, J.

    A specialised quadruple polarimetric camera for space situational awareness, QuadCam, has been built at the Defence Technology Agency (DTA), New Zealand, as part of collaboration with the Defence Science and Technology Laboratory (Dstl), United Kingdom. The design was based on a similar system originally developed at Dstl, with some significant modifications for improved performance. The system is made up of four identical CCD cameras looking in the same direction, but in a different plane of polarisation at 0, 45, 90 and 135 degrees with respect to the reference plane. A standard set of Stokes parameters can be derived from the four images in order to describe the state of polarisation of an object captured in the field of view. The modified design of the DTA QuadCam makes use of four small Raspberry Pi computers, so that each camera is controlled by its own computer in order to speed up the readout process and ensure that the four individual frames are taken simultaneously (to within 100-200 microseconds). In addition, a new firmware was requested from the camera manufacturer so that an output signal is generated to indicate the state of the camera shutter. A specialised GPS unit (also developed at DTA) is then used to monitor the shutter signals from the four cameras and record the actual time of exposure to an accuracy of about 100 microseconds. This makes the system well suited for the observation of fast-moving objects in the low Earth orbit (LEO). The QuadCam is currently mounted on a Paramount MEII robotic telescope mount at the newly built DTA space situational awareness observatory located on Whangaparaoa Peninsula near Auckland, New Zealand. The system will be used for tracking satellites in low Earth orbit and geostationary belt as well. The performance of the camera has been evaluated and a series of test images have been collected in order to derive the polarimetric signatures for selected satellites.

  11. Gas exchange and leaf anatomy of a C3?CAM hybrid, Yucca gloriosa (Asparagaceae)

    OpenAIRE

    Heyduk, Karolina; Burrell, Nia; Lalani, Falak; Leebens-Mack, Jim

    2015-01-01

    While the majority of plants use the typical C3 carbon metabolic pathway, ~6% of angiosperms have adapted to carbon limitation as a result of water stress by employing a modified form of photosynthesis known as Crassulacean acid metabolism (CAM). CAM plants concentrate carbon in the cells by temporally separating atmospheric carbon acquisition from fixation into carbohydrates. CAM has been studied for decades, but the evolutionary progression from C3 to CAM remains obscure. In order to better...

  12. Evaluation of complementary-alternative medicine (CAM) questionnaire development for Indonesian clinical psychologists: A pilot study.

    Science.gov (United States)

    Liem, Andrian; Newcombe, Peter A; Pohlman, Annie

    2017-08-01

    This study aimed to evaluate questionnaire development to measure the knowledge of Complementary-Alternative Medicine (CAM), attitudes towards CAM, CAM experiences, and CAM educational needs of clinical psychologists in Indonesia. A 26-item questionnaire was developed through an extensive literature search. Data was obtained from provisional psychologists from the Master of Professional Clinical Psychology programs at two established public universities in urban areas of Indonesia. To validate the questionnaire, panel reviews by executive members of the Indonesian Clinical Psychology Association (ICPA), experts in health psychology, and experts in public health and CAM provided their professional judgements. The self-reporting questionnaire consisted of four scales including: knowledge of CAM (6 items), attitudes towards CAM (10 items), CAM experiences (4 items), and CAM educational needs (6 items). All scales, except CAM Experiences, were assessed on a 7-point Likert scale. Sixty provisional psychologists were eligible to complete the questionnaire with a response rate of 73% (N=44). The results showed that the CAM questionnaire was reliable (Cronbach's coefficient alpha range=0.62-0.96; item-total correlation range=0.14-0.92) and demonstrated content validity. Following further psychometric evaluation, the CAM questionnaire may provide the evidence-based information to inform the education and practice of Indonesian clinical psychologists. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Synthesis and analysis of coupler curves with combined planar cam ...

    African Journals Online (AJOL)

    Cam and follower mechanisms are widely used to convert a rotary input motion into a controlled reciprocating or oscillating motion as output in machines or robots. As this mechanism has an ability to provide unlimited variety of output motions. Many works are done on the synthesis of coupler curves or path generation ...

  14. Fatigue resistance of CAD/CAM resin composite molar crowns.

    NARCIS (Netherlands)

    Shembish, F.A.; Tong, H.; Kaizer, M.; Janal, M.N.; Thompson, V.P.; Opdam, N.J.M.; Zhang, Y.

    2016-01-01

    OBJECTIVE: To demonstrate the fatigue behavior of CAD/CAM resin composite molar crowns using a mouth-motion step-stress fatigue test. Monolithic leucite-reinforced glass-ceramic crowns were used as a reference. METHODS: Fully anatomically shaped monolithic resin composite molar crowns (Lava

  15. Special Section: Complementary and Alternative Medicine (CAM): Time to Talk

    Science.gov (United States)

    ... to discuss with your health care providers any complementary and alternative medicines you take or are thinking about starting. Photo: ... adults 50 and older use some form of complementary and alternative medicine (CAM). But less than one-third who use ...

  16. The pineapple genome and the evolution of CAM photosynthesis

    Science.gov (United States)

    Pineapple (Ananas comosus (L.) Merr.) is the most economically valuable crop possessing crassulacean acid metabolism (CAM), a photosynthetic carbon assimilation pathway with high water-use efficiency, and the second most important tropical fruit. We sequenced the genomes of pineapple varieties F153 ...

  17. Schools (Students) Exchanging CAD/CAM Files over the Internet.

    Science.gov (United States)

    Mahoney, Gary S.; Smallwood, James E.

    This document discusses how students and schools can benefit from exchanging computer-aided design/computer-aided manufacturing (CAD/CAM) files over the Internet, explains how files are exchanged, and examines the problem of selected hardware/software incompatibility. Key terms associated with information search services are defined, and several…

  18. Mechanical properties and DIC analyses of CAD/CAM materials.

    Science.gov (United States)

    Porto, Thiago; Roperto, Renato; Akkus, Anna; Akkus, Ozan; Porto-Neto, Sizenando; Teich, Sorin; Lang, Lisa; Campos, Edson

    2016-12-01

    This study compared two well-known computer-aided-design/computer-aided-manufactured (CAD/CAM) blocks (Paradigm MZ100 [3M ESPE] and Vitablocs Mark II [Vita] in terms of fracture toughness (Kic), index of brittleness (BI) and stress/strain distributions. Three-point bending test was used to calculate the fracture toughness, and the relationship between the Kic and the Vickers hardness was used to calculate the index of brittleness. Additionally, digital image correlation (DIC) was used to analyze the stress/strain distribution on both materials. The values for fracture toughness obtained under three-point bending were 1.87Pa√m (±0.69) for Paradigm MZ100 and 1.18Pa√m (±0.17) for Vitablocs Mark II. For the index of brittleness, the values for Paradigm and Vitablocs were 73.13μm-1/2 (±30.72) and 550.22μm-1/2 (±82.46). One-way ANOVA was performed to find differences (α=0.05) and detected deviation between the stress/strain distributions on both materials. Both CAD/CAM materials tested presented similar fracture toughness, but, different strain/stress distributions. Both materials may perform similarly when used in CAD/CAM restorations. Key words: Ceramic, CAD/CAM, hybrid materials, composite resin, fracture toughness.

  19. Fabricating Complete Dentures with CAD/CAM and RP Technologies.

    Science.gov (United States)

    Bilgin, Mehmet Selim; Erdem, Ali; Aglarci, Osman Sami; Dilber, Erhan

    2015-06-01

    Two techological approaches for fabricating dentures; computer-aided design and computer-aided manufacturing (CAD/CAM) and rapid prototyping (RP), are combined with the conventional techniques of impression and jaw relation recording to determine their feasibility and applicability. Maxillary and mandibular edentulous jaw models were produced using silicone molds. After obtaining a gypsum working model, acrylic bases were crafted, and occlusal rims for each model were fabricated with previously determined standard vertical and centric relationships. The maxillary and mandibular relationships were recorded with guides. The occlusal rims were then scanned with a digital scanner. The alignment of the maxillary and mandibular teeth was verified. The teeth in each arch were fabricated in one piece, or set, either by CAM or RP. Conventional waxing and flasking was then performed for both methods. These techniques obviate a practitioner's need for technicians during design and provide the patient with an opportunity to participate in esthetic design with the dentist. In addition, CAD/CAM and RP reduce chair time; however, the materials and techniques need further improvements. Both CAD/CAM and RP techniques seem promising for reducing chair time and allowing the patient to participate in esthetics design. Furthermore, the one-set aligned artificial tooth design may increase the acrylic's durability. © 2015 by the American College of Prosthodontists.

  20. Photosynthesis-related characteristics of the midrib and the interveinal lamina in leaves of the C3-CAM intermediate plant Mesembryanthemum crystallinum.

    Science.gov (United States)

    Kuźniak, Elżbieta; Kornas, Andrzej; Kaźmierczak, Andrzej; Rozpądek, Piotr; Nosek, Michał; Kocurek, Maciej; Zellnig, Günther; Müller, Maria; Miszalski, Zbigniew

    2016-06-01

    Leaf veins are usually encircled by specialized bundle sheath cells. In C4 plants, they play an important role in CO2 assimilation, and the photosynthetic activity is compartmentalized between the mesophyll and the bundle sheath. In C3 and CAM (Crassulacean acid metabolism) plants, the photosynthetic activity is generally attributed to the leaf mesophyll cells, and the vascular parenchymal cells are rarely considered for their role in photosynthesis. Recent studies demonstrate that enzymes required for C4 photosynthesis are also active in the veins of C3 plants, and their vascular system contains photosynthetically competent parenchyma cells. However, our understanding of photosynthesis in veins of C3 and CAM plants still remains insufficient. Here spatial analysis of photosynthesis-related properties were applied to the midrib and the interveinal lamina cells in leaves of Mesembryanthemum crystallinum, a C3-CAM intermediate plant. The midrib anatomy as well as chloroplast structure and chlorophyll fluorescence, diurnal gas exchange profiles, the immunoblot patterns of PEPC (phosphoenolpyruvate carboxylase) and RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase), H2O2 localization and antioxidant enzyme activities were compared in the midrib and in the interveinal mesophyll cells in leaves of C3 and CAM plants. Leaf midribs were structurally competent to perform photosynthesis in C3 and CAM plants. The midrib chloroplasts resembled those in the bundle sheath cells of C4 plants and were characterized by limited photosynthetic activity. The metabolic roles of midrib chloroplasts differ in C3 and CAM plants. It is suggested that in leaves of C3 plants the midrib chloroplasts could be involved in the supply of CO2 for carboxylation, and in CAM plants they could provide malate to different metabolic processes and mediate H2O2 signalling. © The Author 2016. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For

  1. Improved Methodology for Semi-Automated Identification of Plankton and Biovolume Estimation Using a Digital Imaging Flow Cytometer (FlowCam)

    Science.gov (United States)

    Wright, H. A.; Nelson, H.; Dalton, B.

    2016-02-01

    Responding to the need for the "rapid counting, imaging and measurement of individual plankton cells…in natural populations", researchers at the Bigelow Laboratory for Ocean Sciences in 1999 built and installed the first FlowCam, an imaging particle analyzer designed specifically to support aquatic microbial research. Since 1999 over 300 FlowCams in 40+ countries have been put to use for the purpose of the study and monitoring of microorganisms in both fresh and marine systems. Building upon advances in technology, input from the user community, and expanded resources, engineers at Fluid Imaging Technologies, manufacturer of the FlowCam, have designed the 4th Generation FlowCam. Informally referred to as the `High Sensitivity FlowCam' (HSFC), the instrument provides more precise information over earlier versions - especially with regard to fluorescence data and size and concentration information. The HSFC has an improved method for sample introduction, and is simpler to use. Included among the next-gen FlowCams is an optics configuration (specific laser and optical filters) allowing for the detection of phycocyanin, thus providing for an improved method to identify and characterize cyanobacteria, and a version that can analyze zooplankton up to 5mm in size. In addition to a hardware overhaul, the image recognition algorithm and user interface for identifying and classifying organisms has been redesigned, as has the method to estimate biovolume. Included will be an overview of the various new designs, how they work, along with a review of data from the HSFC FlowCam.

  2. [Effect of interlocking intramedullary nail in treatment of open tibial and fibula fractures].

    Science.gov (United States)

    Ji, Jianfei; Zhao, Yinsong; He, Xueyu; Zhou, Yang

    2009-03-01

    To determine the effect of interlocking intramedullary nail in treatment of open tibial and fibula fractures and analyze the method to promote the bone union. From December 2003 to June 2006, thirty-five patients with open tibial and fibula fracture were treated with emergency debridement, interlocked intramedullary fixation for tibia and fixed fibula at the same time. During operation, the bone marrow was collected and grafted into the fracture gaps. Among them, there were 27 males and 8 females, involving in 22 left legs and 13 right legs. Their ages ranged from 19 to 65 years, with an average of 34.7 years. The location of fracture was the middle of the tibia and fibula in 16 cases, the distal 1/3 of the tibia and fibula in 12 cases and the proximal 1/3 in 7 cases. According to the Gustilo classification of open injuries, there were 7 cases of type I, 19 cases of type II, 8 cases of type III a and 1 case of type III b. The mean range of knee motion was 48.3 degrees (45-70 degrees). The mean time from injury to operation was 4.3 hours (50 minutes to 7 hours). The mean operation time was 94 minutes (60-132 minutes) and the mean blood loss was 122 mL (100-350 mL). The wound healed by first intention in 32 patients. Incision was sutured in 2 cases of type III a fractures after operation 4 days, gastrocnemius flap graft was performed in 1 case of type III b fracture 1 week after operation. They all achieve good healing. No fractures split off, no iatrogenic nerve and vascular injury occurred, no osteofascial compartment syndromes or deep vein thrombus happened. Tension blisters appeared in 1 case of type II fracture after operation and subsided after 5 days. Patients were followed up for 14-43 months (mean 22 months). The X-ray films showed that fracture union was observe in 30 cases after 14 weeks of operation, in 3 cases after 18 weeks and in 1 case after 22 weeks of operation. The fractures union time was 15.2 weeks on average. About 2 cm nonunion in lateral

  3. ChemCam analysis of Martian fine dust

    Science.gov (United States)

    Lasue, Jeremie; Mangold, Nicolas; Cousin, Agnes; Meslin, Pierre-Yves; Wiens, Roger; Gasnault, Olivier; Rapin, William; Schroder, Susanne; Ollila, Ann; Fabre, Cécile; Berger, Gilles; Le Mouélic, Stéphane; Dehouck, Erwin; Forni, Olivier; Maurice, Sylvestre; Anderson, Ryan; Bridges, Nathan; Clark, Benton; Clegg, Samuel; d'Uston, Claude; Goetz, Walter; Johnson, Jeffrey R.; Lanza, Nina; Madsen, Morten; Melikechi, Noureddine; Newsom, Horton; Sautter, Violaine; Martin-Torres, Javier; Zorzano, Maria-Paz; MSL Science Team

    2016-10-01

    In this work, we examine the chemical composition of dust observed by the Chemistry Camera (ChemCam) instrument onboard the Mars Science Laboratory (MSL) rover at Gale Crater. The Laser Induced Breakdown Spectroscopy technique analyses samples without preparation, which allows detection of the elemental composition of surface deposits. Mars aeolian fine dust (planet and contributes to the local geology analyzed by MSL. Its composition can also be retrieved on the ChemCam Calibration Targets (CCCT) by subtraction of the well characterized CCCT spectra. The CCCT include eight glasses and ceramics that have been generated to simulate Martian rocks of interest and two targets of a single element (graphite for carbon and an alloy of titanium). ChemCam passive spectroscopy also indicates varying deposition of the dust cover on the CCCT.Major elements are quantified and shown to be very similar to the fine soils encountered at Gale crater. The composition is also similar to the soils and fine dust measured by APXS for the elements common to both instruments. The minor elements quantified by ChemCam (Ba, Sr, Rb, Li, Mn, Cr) are within the range of soil surveys, but we see a higher concentration of Li than in other types of remotely characterized targets. Sulfur is possibly detected at the ChemCam limit of detection. Hydrogen is clearly identified, indicating that this fine dust is a contributor to the H content of the martian soils, as also detected by the SAM and CheMin instruments, and provides constraints as to which fraction of the Martian surface is hydrated and altered. In conclusion, the finest fraction of dust particles on the surface of Mars contains hydrated components mixed intimately within the fine aeolian dust fraction, suggesting that this dust likely originates from mechanical weathering of altered grains.

  4. Abnormal placental development and early embryonic lethality in EpCAM-null mice.

    Science.gov (United States)

    Nagao, Keisuke; Zhu, Jianjian; Heneghan, Mallorie B; Hanson, Jeffrey C; Morasso, Maria I; Tessarollo, Lino; Mackem, Susan; Udey, Mark C

    2009-12-31

    EpCAM (CD326) is encoded by the tacstd1 gene and expressed by a variety of normal and malignant epithelial cells and some leukocytes. Results of previous in vitro experiments suggested that EpCAM is an intercellular adhesion molecule. EpCAM has been extensively studied as a potential tumor marker and immunotherapy target, and more recent studies suggest that EpCAM expression may be characteristic of cancer stem cells. To gain insights into EpCAM function in vivo, we generated EpCAM -/- mice utilizing an embryonic stem cell line with a tacstd1 allele that had been disrupted. Gene trapping resulted in a protein comprised of the N-terminus of EpCAM encoded by 2 exons of the tacstd1 gene fused in frame to betageo. EpCAM +/- mice were viable and fertile and exhibited no obvious abnormalities. Examination of EpCAM +/- embryos revealed that betageo was expressed in several epithelial structures including developing ears (otocysts), eyes, branchial arches, gut, apical ectodermal ridges, lungs, pancreas, hair follicles and others. All EpCAM -/- mice died in utero by E12.5, and were small, developmentally delayed, and displayed prominent placental abnormalities. In developing placentas, EpCAM was expressed throughout the labyrinthine layer and by spongiotrophoblasts as well. Placentas of EpCAM -/- embryos were compact, with thin labyrinthine layers lacking prominent vascularity. Parietal trophoblast giant cells were also dramatically reduced in EpCAM -/- placentas. EpCAM was required for differentiation or survival of parietal trophoblast giant cells, normal development of the placental labyrinth and establishment of a competent maternal-fetal circulation. The findings in EpCAM-reporter mice suggest involvement of this molecule in development of vital organs including the gut, kidneys, pancreas, lungs, eyes, and limbs.

  5. Comparative multicenter study of treatment of multi-fragmented tibial diaphyseal fractures with nonreamed interlocking nails and with bridging plates.

    Science.gov (United States)

    Fernandes, Hélio Jorge Alvachian; Sakaki, Marcos Hideyo; Silva, Jorge dos Santos; dos Reis, Fernando Baldy; Zumiotti, Arnaldo Valdir

    2006-08-01

    A prospective, randomized study to compare patients with closed, multi-fragmented tibial diaphyseal fractures treated using one of two fixation methods undertaken during minimally invasive surgery: nonreamed interlocking intramedullary nails or bridging plates. Forty-five patients were studied; 22 patients were treated with bridging plates, 23 with interlocking nails without reaming. All fractures were Type B and C (according to the AO classification). Clinical and radiographic healing occurred in all cases. No cases of infection occurred. The healing time for patients who received nails was longer (4.32 weeks on average) than the healing time for those who received plates (P = 0.026). No significant differences were observed between the two methods regarding ankle mobility for patients in the two groups. The healing time was shorter with the bridging plate technique, although no significant functional differences were found.

  6. Evolution of CAM and C4 carbon-concentrating mechanisms

    Science.gov (United States)

    Keeley, Jon E.; Rundel, Philip W.

    2003-01-01

    Mechanisms for concentrating carbon around the Rubisco enzyme, which drives the carbon-reducing steps in photosynthesis, are widespread in plants; in vascular plants they are known as crassulacean acid metabolism (CAM) and C4 photosynthesis. CAM is common in desert succulents, tropical epiphytes, and aquatic plants and is characterized by nighttime fixation of CO2. The proximal selective factor driving the evolution of this CO2-concentrating pathway is low daytime CO2, which results from the unusual reverse stomatal behavior of terrestrial CAM species or from patterns of ambient CO2 availability for aquatic CAM species. In terrestrials the ultimate selective factor is water stress that has selected for increased water use efficiency. In aquatics the ultimate selective factor is diel fluctuations in CO2 availability for palustrine species and extreme oligotrophic conditions for lacustrine species. C4 photosynthesis is based on similar biochemistry but carboxylation steps are spatially separated in the leaf rather than temporally as in CAM. This biochemical pathway is most commonly associated with a specialized leaf anatomy known as Kranz anatomy; however, there are exceptions. The ultimate selective factor driving the evolution of this pathway is excessively high photorespiration that inhibits normal C3 photosynthesis under high light and high temperature in both terrestrial and aquatic habitats. CAM is an ancient pathway that likely has been present since the Paleozoic era in aquatic species from shallow-water palustrine habitats. While atmospheric CO2 levels have undoubtedly affected the evolution of terrestrial plant carbon-concentrating mechanisms, there is reason to believe that past atmospheric changes have not played as important a selective role in the aquatic milieu since palustrine habitats today are not generally carbon sinks, and the selective factors driving aquatic CAM are autogenic. Terrestrial CAM, in contrast, is of increasing selective value under

  7. Metal-organic and supramolecular architectures based on mechanically interlocked molecules

    Science.gov (United States)

    Fernando, Isurika Rosini

    The focus of this work is on mechanically interlocked molecules (MIMs), which have unusual physicochemical and mechanical properties with potential applications in nano-scale/molecular devices and high strength materials. Rotaxanes, for example, consist of an axle-like molecule threaded through a wheel-like molecule, with bulky groups at the two ends of the axle preventing the wheel from dissociating. The position of the wheel along the axle can be switched in a controllable and reversible manner by applying external stimuli, a feature that might lead to the next generation of computers. Molecularly woven materials (MWMs), another example of molecules with mechanically interlocked features, are predicted to be unprecedentedly strong while being lightweight and flexible. With the ultimate goal of achieving control over the functioning of molecular devices in the solid state, a variety of pseudorotaxane building blocks were prepared and characterized, including a novel, rare blue-colored motif. The temperature-dependent assembly/disassembly of pseudorotaxanes was exploited for the construction of single-wavelength colorimetric temperature sensors over a 100 °C window. Pseudorotaxanes based on aromatic crown ether wheels and disubstituted 4,4'-bipyridinium axles were converted into rotaxanes upon binding to metal complexes (zinc, cadmium, mercury, copper, cobalt), and the formation of ordered crystalline arrays was studied in the solid state. The columnar organization of pseudorotaxanes by Hg2X6 2-- complexes (X = Cl, Br, I), leading to unprecedented dichroic (blue/red) rotaxane crystals, was demonstrated for the first time. From the crystal structures studied it became apparent that negatively charged metal complexes are needed for successful assembly with the positively charged pseudorotaxane units. To be able to use the more common, positively charged metal ions for rotaxane framework construction, neutral and negatively charged pseudorotaxanes were synthesized

  8. An integrated CAD/CAM/robotic milling method for custom cementless femoral prostheses.

    Science.gov (United States)

    Wen-ming, Xi; Ai-min, Wang; Qi, Wu; Chang-hua, Liu; Jian-fei, Zhu; Fang-fang, Xia

    2015-09-01

    Aseptic loosening is the primary cause of cementless femoral prosthesis failure and is related to the primary stability of the cementless femoral prosthesis in the femoral cavity. The primary stability affects both the osseointegration and the long-term stability of cementless femoral prostheses. A custom cementless femoral prosthesis can improve the fit and fill of the prosthesis in the femoral cavity and decrease the micromotion of the proximal prosthesis such that the primary stability of the custom prosthesis can be improved, and osseointegration of the proximal prosthesis is achieved. These results will help to achieve long-term stability in total hip arthroplasty (THA). In this paper, we introduce an integrated CAD/CAM/robotic method of milling custom cementless femoral prostheses. The 3D reconstruction model uses femoral CT images and 3D design software to design a CAD model of the custom prosthesis. After the transformation matrices between two units of the robotic system are calibrated, consistency between the CAM software and the robotic system can be achieved, and errors in the robotic milling can be limited. According to the CAD model of the custom prosthesis, the positions of the robotic tool points are produced by the CAM software of the CNC machine. The normal vector of the three adjacent robotic tool point positions determines the pose of the robotic tool point. In conclusion, the fit rate of custom pig femur stems in the femoral cavities was 90.84%. After custom femoral prostheses were inserted into the femoral cavities, the maximum gaps between the prostheses and the cavities measured less than 1 mm at the diaphysis and 1.3 mm at the metaphysis. Copyright © 2015 IPEM. Published by Elsevier Ltd. All rights reserved.

  9. Topology Engineering of Proteins in Vivo Using Genetically Encoded, Mechanically Interlocking SpyX Modules for Enhanced Stability.

    Science.gov (United States)

    Liu, Dong; Wu, Wen-Hao; Liu, Ya-Jie; Wu, Xia-Ling; Cao, Yang; Song, Bo; Li, Xiaopeng; Zhang, Wen-Bin

    2017-05-24

    Recombinant proteins are traditionally limited to linear configuration. Herein, we report in vivo protein topology engineering using highly efficient, mechanically interlocking SpyX modules named AXB and BXA. SpyX modules are protein domains composed of p53dim (X), SpyTag (A), and SpyCatcher (B). The p53dim guides the intertwining of the two nascent protein chains followed by autocatalytic isopeptide bond formation between SpyTag and SpyCatcher to fulfill the interlocking, leading to a variety of backbone topologies. Direct expression of AXB or BXA produces protein catenanes with distinct ring sizes. Recombinant proteins containing SpyX modules are obtained either as mechanically interlocked obligate dimers if the protein of interest is fused to the N- or C-terminus of SpyX modules, or as star proteins if the protein is fused to both N- and C-termini. As examples, cellular syntheses of dimers of (GB1) 2 (where GB1 stands for immunoglobulin-binding domain B1 of streptococcal protein G) and of four-arm elastin-like star proteins were demonstrated. Comparison of the catenation efficiencies in different constructs reveals that BXA is generally much more effective than AXB, which is rationalized by the arrangement of three domains in space. Mechanical interlocking induces considerable stability enhancement. Both AXB and BXA have a melting point ∼20 °C higher than the linear controls and the BXA catenane has a melting point ~2 °C higher than the cyclic control BX'A. Notably, four-arm elastin-like star proteins demonstrate remarkable tolerance against trypsin digestion. The SpyX modules provide a convenient and versatile approach to construct unconventional protein topologies via the "assembly-reaction" synergy, which opens a new horizon in protein science for stability enhancement and function reinforcement via topology engineering.

  10. A STUDY OF EXCHANGE OF FAILED IMPLANT WITH INTRAMEDULLARY INTERLOCKING NAIL IN FRACTURES OF FEMUR AND TIBIA

    OpenAIRE

    Rapaka; Maheshwar; Gouru

    2015-01-01

    The aim of the fracture treatment is to achieve union with timely functional recovery. Internal fixation with adherence to strict biomechanical principles is often required to achieve this. However, a fixation device may fail to hold a redu ced fracture until union, giving rise to non - union or delayed union with implant failure. The aim of this study was to see the efficacy of exchange of failed implant with an intra - medullary interlocking nail. PATIENTS AND ...

  11. A comparative study of intramedullary interlocking nailing and minimally invasive plate osteosynthesis in extra articular distal tibial fractures

    OpenAIRE

    Arup K Daolagupu; Ashwani Mudgal; Vikash Agarwala; Kaushik K Dutta

    2017-01-01

    Background: Extraarticular distal tibial fractures are among the most challenging fractures encountered by an orthopedician for treatment because of its subcutaneous location, poor blood supply and decreased muscular cover anteriorly, complications such as delayed union, nonunion, wound infection, and wound dehiscence are often seen as a great challenge to the surgeon. Minimally invasive plate osteosynthesis (MIPO) and intramedullary interlocking nail (IMLN) are two well-accepted and effectiv...

  12. 46 CFR 113.35-7 - Electric engine order telegraph systems; operations.

    Science.gov (United States)

    2010-10-01

    ... ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-7 Electric... mechanically interlocked to effect synchronous operation, the requirements of § 113.35-13 must be met. (c...

  13. A comparative study of intramedullary interlocking nailing and minimally invasive plate osteosynthesis in extra articular distal tibial fractures.

    Science.gov (United States)

    Daolagupu, Arup K; Mudgal, Ashwani; Agarwala, Vikash; Dutta, Kaushik K

    2017-01-01

    Extraarticular distal tibial fractures are among the most challenging fractures encountered by an orthopedician for treatment because of its subcutaneous location, poor blood supply and decreased muscular cover anteriorly, complications such as delayed union, nonunion, wound infection, and wound dehiscence are often seen as a great challenge to the surgeon. Minimally invasive plate osteosynthesis (MIPO) and intramedullary interlocking nail (IMLN) are two well-accepted and effective methods, but each has been historically related to complications. This study compares clinical and radiological outcome in extraarticular distal tibia fractures treated by intramedullary interlocking nail (IMLN) and minimally invasive plate osteosynthesis (MIPO). 42 patients included in this study, 21 underwent IMLN and 21 were treated with MIPO who met the inclusion criteria and operated between June 2014 and May 2015. Patients were followed up for clinical and radiological evaluation. In IMLN group, average union time was 18.26 weeks compared to 21.70 weeks in plating group which was significant ( P plating group. Lesser complications in terms of implant irritation, ankle stiffness, and infection, were seen in interlocking group as compared to plating group. Average functional outcome according to American Orthopedic Foot and Ankle Society score was measured which came out to be 96.67. IMLN group was associated with lesser duration of surgery, earlier weight bearing and union rate, lesser incidence of infection and implant irritation which makes it a preferable choice for fixation of extra-articular distal tibial fractures. However, larger randomized controlled trials are required for confirming the results.

  14. Shared origins of a key enzyme during the evolution of C4 and CAM metabolism

    Science.gov (United States)

    Christin, Pascal-Antoine; Arakaki, Monica; Osborne, Colin P.; Bräutigam, Andrea; Sage, Rowan F.; Hibberd, Julian M.; Kelly, Steven; Covshoff, Sarah; Wong, Gane Ka-Shu; Hancock, Lillian; Edwards, Erika J.

    2014-01-01

    CAM and C4 photosynthesis are two key plant adaptations that have evolved independently multiple times, and are especially prevalent in particular groups of plants, including the Caryophyllales. We investigate the origin of photosynthetic PEPC, a key enzyme of both the CAM and C4 pathways. We combine phylogenetic analyses of genes encoding PEPC with analyses of RNA sequence data of Portulaca, the only plants known to perform both CAM and C4 photosynthesis. Three distinct gene lineages encoding PEPC exist in eudicots (namely ppc-1E1, ppc-1E2 and ppc-2), one of which (ppc-1E1) was recurrently recruited for use in both CAM and C4 photosynthesis within the Caryophyllales. This gene is present in multiple copies in the cacti and relatives, including Portulaca. The PEPC involved in the CAM and C4 cycles of Portulaca are encoded by closely related yet distinct genes. The CAM-specific gene is similar to genes from related CAM taxa, suggesting that CAM has evolved before C4 in these species. The similar origin of PEPC and other genes involved in the CAM and C4 cycles highlights the shared early steps of evolutionary trajectories towards CAM and C4, which probably diverged irreversibly only during the optimization of CAM and C4 phenotypes. PMID:24638902

  15. The Unsuspecting CAM User: Cancer patients and the changing nature of holistic health

    Directory of Open Access Journals (Sweden)

    A M. Kabel

    2014-05-01

    Full Text Available The number of cancer patients using complementary and alternative medicine (CAM in the United States is growing, yet little is known about the meaning these activities have for users. Current literature supports the assumption that stigma surrounding CAM and holistic health practices are responsible for the reluctance of many cancer patients to self-identify as CAM users. This study explored the frequency of use, and familiarity with CAM among 25 female patients at a Midwestern oncology clinic. Findings suggest that patients need to be asked about CAM use multiple times and in multiple formats to gain an accurate assessment. Also, the assumptions about stigma may no longer be the reason patients are less than forthcoming about CAM use. The rise of integrative medicine and shifting boundaries of the holistic health movement may be equally, or in some cases, more responsible for the reluctance for CAM users to self-identify.

  16. Distortion of CAD-CAM-fabricated implant-fixed titanium and zirconia complete dental prosthesis frameworks.

    Science.gov (United States)

    Al-Meraikhi, Hadi; Yilmaz, Burak; McGlumphy, Edwin; Brantley, William A; Johnston, William M

    2018-01-01

    Computer-aided design and computer-aided manufacturing (CAD-CAM)-fabricated titanium and zirconia implant-supported fixed dental prostheses have become increasingly popular for restoring patients with complete edentulism. However, the distortion level of these frameworks is not well known. The purpose of this in vitro study was to compare the 3-dimensional (3D) distortion of CAD-CAM zirconia and titanium implant-fixed screw-retained complete dental prostheses. A master edentulous model with 4 implants at the positions of the maxillary first molars and canines was used. Multiunit abutments (Nobel Biocare) secured to the model were digitally scanned using scan bodies and a laboratory scanner (S600 ARTI; Zirkonzahn). Titanium (n=5) and zirconia (n=5) frameworks were milled using a CAD-CAM system (Zirkonzahn M1; Zirkonzahn). All frameworks were scanned using an industrial computed tomography (CT) scanner (Nikon/X-Tek XT H 225kV MCT Micro-Focus). The direct CT scans were reconstructed to generate standard tessellation language (STL) files. To calculate the 3D distortion of the frameworks, STL files of the CT scans were aligned to the CAD model using a sum of the least squares best-fit algorithm. Surface comparison points were placed on the CAD model on the midfacial aspect of all teeth. The 3D distortion of each direct scan to the CAD model was calculated. In addition, color maps of the scan-to-CAD comparison were constructed using a ±0.500 mm color scale range. Both materials exhibited distortion; however, no significant difference was found in the amount of distortion from the CAD model between the materials (P=.747). Absolute values of deviations from the CAD model were evident in the x and y plane and less so in the z direction. Zirconia and titanium frameworks showed similar 3D distortion compared with the CAD model for the tested CAD-CAM and implant systems. The distortion was more pronounced in the horizontal and sagittal plane than in the vertical plane

  17. Biocalcification using Ureolytic Bacteria (UB) for strengthening Interlocking Compressed Earth Blocks (ICEB)

    Science.gov (United States)

    Zamer, M. M.; Irwan, J. M.; Othman, N.; Faisal, S. K.; Anneza, L. H.; Alshalif, A. F.; Teddy, T.

    2018-02-01

    Interlocking compressed earth blocks (ICEB) are soil based blocks that allows for mortarless construction. This characteristic resulted to faster the process of building walls and required less skilled labor as the blocks are laid dry and lock into place. Recently, implementation in using bacteria as construction material improvement is vigorously used in research in order pursuit the sustainable construction works. This paper provide the results of ureolytic bacteria (UB) throughout enrichment process in soil condition to acclimatize the ICEB environment, compressive strength of 1%, 3% and 5% UB and SEM analysis of ICEB. The bacteria were added as partial replacement of limestone water in ICEB. The results showed the optimal growth achieved based on the days and absorbance from optical density (OD) test which are in 12th days with absorbance of 0.55 whereas the results for strength shows the increment of 15.25% with 5% UB on 28th days of testing compared to control specimen. Therefore this study hopes that positive results from the UB as improving in strength of ICEB which will lead to improve others ICEB properties and others construction materials.

  18. Laboratory analysis of the infiltration capacity of interlocking concrete block pavements in car parks.

    Science.gov (United States)

    Sañudo-Fontaneda, Luis A; Rodriguez-Hernandez, Jorge; Vega-Zamanillo, Angel; Castro-Fresno, Daniel

    2013-01-01

    Interlocking concrete block pavements (ICBPs) have been widely used in car parks to reduce runoff. Researches have demonstrated that clogging is the most influential factor in the reduction of the infiltration capacity of this type of permeable pavement. Nevertheless, there is no laboratory study of the infiltration performance of ICBPs that combines clogging levels with variables related with the topography of car parks such as runoff surface length (R(SL)) and surface slope (S(S)). This paper studies the infiltration behaviour of ICBP during their operational life in a car park using an improved version of the Cantabrian Fixed (CF) Infiltrometer. This laboratory device simulates direct rainfall and runoff from adjacent impervious areas over an ICBPs surface of 0.25 m(2) for different slopes (0, 3, 5, 7 and 10%) and three scenarios of clogging (surface newly built, surface clogged and surface clogged with maintenance). This paper presents the results of the tests and a statistical analysis based on three regression models (corresponding to each clogging scenario) depending on the R(SL) and S(S) variables. All models passed a confidence level of 95%, presenting high R(2) values and showing that R(SL) is a more influential variable than the S(S) for all clogging scenarios.

  19. A Simple Field Test to Evaluate the Maintenance Requirements of Permeable Interlocking Concrete Pavements

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    Terry Lucke

    2015-05-01

    Full Text Available Adequate infiltration through Permeable Interlocking Concrete Pavements (PICPs is critical to their hydraulic and stormwater treatment performance. Infiltration is affected by clogging caused by the trapping of fines in the PICP surface, which, over time, reduces treatment performance. Clogging can be reduced by periodic maintenance such as vacuum sweeping and/or pressure washing. Maintenance requirements can be indicated by measuring reduced infiltration rates. This paper compared infiltration results using the standard test (C1781M-14a with the results of a new stormwater infiltration field test (SWIFT developed in Australia to evaluate the maintenance requirements of PICPs. A strong correlation (Pearson’s r = −0.714 was found between results using the two methods. This study found that the SWIFT was a reliable method for estimating the degree of clogging of PICPs while successfully overcoming some of the problems with the more technical existing test methodology such as horizontal water leakage (use of sealant, unrealistic pressure heads, speed of test, and portability. The SWIFT test is a simple, fast and inexpensive way for asset managers and local government employees to quickly assess the maintenance requirements of PICP installations in the field.

  20. Comparing Two Methods of Determining Infiltration Rates of Permeable Interlocking Concrete Pavers

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    Peter W.B.Nichols

    2014-08-01

    Full Text Available Adequate infiltration through Permeable Interlocking Concrete Pavements (PICPs is critical to their hydraulic performance. Detected by monitoring infiltration performance, reduced infiltration rates can indicate that maintenance is required. Measurement of infiltration rates has previously been problematic on PICPs because of a lack of accepted standard methodologies and the practical difficulties in modifying existing testing methodologies. On large sites, standard methodologies necessitate multiple measurements to achieve accuracy. Standard methods also contend with practical issues such as sealing the rings to the surface to prevent lateral water flow. This study examined the performance of two PICP surface infiltration rate measurement methods: a modified double-ring infiltrometer (DRIT, and a specially designed rainfall simulation infiltrometer (RSIT. A positive correlation (R2 = 0.85 of results was found between the two, demonstrating that the RSIT was comparable to the DRIT. The modified DRIT produced surface infiltration results approximately 60% higher than the RSIT results. The RSIT provided lower variation between tests, requiring fewer measurements in large sites whilst still maintaining accuracy, thereby improving testing efficiency. The new RSIT method also eliminates some of the practical difficulties with existing methodologies such as unrealistic pressure heads artificially increasing infiltration rates, and the use of sealant under test measurement infiltration rings.