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Sample records for californium 248

  1. Accurate determination of Curium and Californium isotopic ratios by inductively coupled plasma quadrupole mass spectrometry (ICP-QMS) in 248Cm samples for transmutation studies

    Energy Technology Data Exchange (ETDEWEB)

    Gourgiotis, A.; Isnard, H.; Aubert, M.; Dupont, E.; AlMahamid, I.; Cassette, P.; Panebianco, S.; Letourneau, A.; Chartier, F.; Tian, G.; Rao, L.; Lukens, W.

    2011-02-01

    The French Atomic Energy Commission has carried out several experiments including the mini-INCA (INcineration of Actinides) project for the study of minor-actinide transmutation processes in high intensity thermal neutron fluxes, in view of proposing solutions to reduce the radiotoxicity of long-lived nuclear wastes. In this context, a Cm sample enriched in {sup 248}Cm ({approx}97 %) was irradiated in thermal neutron flux at the High Flux Reactor (HFR) of the Laue-Langevin Institute (ILL). This work describes a quadrupole ICP-MS (ICP-QMS) analytical procedure for precise and accurate isotopic composition determination of Cm before sample irradiation and of Cm and Cf after sample irradiation. The factors that affect the accuracy and reproducibility of isotopic ratio measurements by ICP-QMS, such as peak centre correction, detector dead time, mass bias, abundance sensitivity and hydrides formation, instrumental background, and memory blank were carefully evaluated and corrected. Uncertainties of the isotopic ratios, taking into account internal precision of isotope ratio measurements, peak tailing, and hydrides formations ranged from 0.3% to 1.3%. This uncertainties range is quite acceptable for the nuclear data to be used in transmutation studies.

  2. Spontaneous Partitioning of Californium from Curium: Curious Cases from the Crystallization of Curium Coordination Complexes

    Energy Technology Data Exchange (ETDEWEB)

    Cary, Samantha K.; Silver, Mark A.; Liu, Guokui; Wang, Jamie C.; Bogart, Justin A.; Stritzinger, Jared T.; Arico, Alexandra A.; Hanson, Kenneth; Schelter, Eric J.; Albrecht-Schmitt, Thomas E.

    2015-12-07

    The reaction of 248CmCl3 with excess 2,6-pyridinedicarboxylic acid (DPA) under mild solvothermal conditions results in crystallization of the tris-chelate complex Cm(HDPA)3·H2O. Approximately half of the curium remains in solution at the end of this process, and evaporation of the mother liquor results in crystallization of the bis-chelate complex [Cm(HDPA)- (H2DPA)(H2O)2Cl]Cl·2H2O. 248Cm is the daughter of the α decay of 252Cf and is extracted in high purity from this parent. However, trace amounts of 249,250,251Cf are still present in all samples of 248Cm. During the crystallization of Cm(HDPA)3·H2O and [Cm(HDPA)(H2DPA)(H2O)2Cl]Cl·2H2O, californium(III) spontaneously separates itself from the curium complexes and is found doped within crystals of DPA in the form of Cf(HDPA)3. These results add to the growing body of evidence that the chemistry of californium is fundamentally different from that of earlier actinides.

  3. Californium Electrodepositions at Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Boll, Rose Ann [ORNL

    2015-01-01

    Electrodepositions of californium isotopes were successfully performed at Oak Ridge National Laboratory (ORNL) during the past year involving two different types of deposition solutions, ammonium acetate (NH4C2H3O2) and isobutanol ((CH3)2CHCH2OH). A californium product that was decay enriched in 251Cf was recovered for use in super-heavy element (SHE) research. This neutron-rich isotope, 251Cf, provides target material for SHE research for the potential discovery of heavier isotopes of Z=118. The californium material was recovered from aged 252Cf neutron sources in storage at ORNL. These sources have decayed for over 30 years, thus providing material with a very high 251Cf-to-252Cf ratio. After the source capsules were opened, the californium was purified and then electrodeposited using the isobutanol method onto thin titanium foils for use in an accelerator at the Joint Institute for Nuclear Research in Dubna, Russia. Another deposition method, ammonium acetate, was used to produce a deposition containing 1.7 0.1 Ci of 252Cf onto a stainless steel substrate. This was the largest single electrodeposition of 252Cf ever prepared. The 252Cf material was initially purified using traditional ion exchange media, such as AG50-AHIB and AG50-HCl, and further purified using a TEVA-NH4SCN system to remove any lanthanides, resulting in the recovery of 3.6 0.1 mg of purified 252Cf. The ammonium acetate deposition was run with a current of 1.0 amp, resulting in a 91.5% deposition yield. Purification and handling of the highly radioactive californium material created additional challenges in the production of these sources.

  4. Historical Review of Californium-252 Discovery and Development

    Science.gov (United States)

    Stoddard, D. H.

    1985-01-01

    This paper discusses the discovery and history of californium 252. This isotope may be synthesized by irradiating plutonium 239, plutonium 242, americium 243, or curium 244 with neutrons in a nuclear reactor. Various experiments and inventions involving Cf conducted at the Savannah River Plant are discussed. The evolution of radiotherapy using californium 252 is reviewed. (PLG)

  5. Production, Distribution, and Applications of Californium-252 Neutron Sources

    Energy Technology Data Exchange (ETDEWEB)

    Balo, P.A.; Knauer, J.B.; Martin, R.C.

    1999-10-03

    The radioisotope {sup 252}Cf is routinely encapsulated into compact, portable, intense neutron sources with a 2.6-year half-life. A source the size of a person's little finger can emit up to 10{sup 11} neutrons/s. Californium-252 is used commercially as a reliable, cost-effective neutron source for prompt gamma neutron activation analysis (PGNAA) of coal, cement, and minerals, as well as for detection and identification of explosives, laud mines, and unexploded military ordnance. Other uses are neutron radiography, nuclear waste assays, reactor start-up sources, calibration standards, and cancer therapy. The inherent safety of source encapsulations is demonstrated by 30 years of experience and by U.S. Bureau of Mines tests of source survivability during explosions. The production and distribution center for the U. S Department of Energy (DOE) Californium Program is the Radiochemical Engineering Development Center (REDC) at Oak Ridge National Laboratory (ORNL). DOE sells The radioisotope {sup 252}Cf is routinely encapsulated into compact, portable, intense neutron sources with a 2.6- year half-life. A source the size of a person's little finger can emit up to 10 neutrons/s. Californium-252 is used commercially as a reliable, cost-effective neutron source for prompt gamma neutron activation analysis (PGNAA) of coal, cement, and minerals, as well as for detection and identification of explosives, laud mines, and unexploded military ordnance. Other uses are neutron radiography, nuclear waste assays, reactor start-up sources, calibration standards, and cancer therapy. The inherent safety of source encapsulations is demonstrated by 30 years of experience and by U.S. Bureau of Mines tests of source survivability during explosions. The production and distribution center for the U. S Department of Energy (DOE) Californium Program is the Radiochemical Engineering Development Center (REDC) at Oak Ridge National Laboratory(ORNL). DOE sells {sup 252}Cf to commercial

  6. 14 CFR 125.248 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false 125.248 Section 125.248 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS AND...; AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance § 125.248...

  7. 7 CFR 248.3 - Administration.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Administration. 248.3 Section 248.3 Agriculture... CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.3 Administration. (a) Delegation to FNS. Within the Department, FNS shall act on behalf of the Department in the administration...

  8. Teratogenic effect of Californium-252 irradiation in rats

    Energy Technology Data Exchange (ETDEWEB)

    Satow, Yukio; Lee, Juing-Yi; Hori, Hiroshi; Okuda, Hiroe; Tsuchimoto, Shigeo; Sawada, Shozo; Yokoro, Kenjiro (Hiroshima Univ. (Japan). Research Inst. for Nuclear Medicine and Biology)

    1989-06-01

    The teratogenicity of Californium-252 (Cf-252) irradiation which generates approximately 70% 2.3 MeV fast neutron and 30% gamma rays was evaluated. A single whole body exposure of Cf-252 at various doses was given to pregnant rats on day 8 or 9 of pregnancy, followed by microscopic autopsy of the fetuses at the terminal stage of pregnancy to search for external and internal malformations. For comparison, pregnant rats were irradiated with various doses of Cobalt-60 (Co-60) standard gamma rays at the same dose rate (1 rad/min.). The doses were 20-120 rad of Cf-252 and 80-220 rad of Co-60. Using frequency of radiation induced malformations observed on day 8 of pregnancy as an index, relative biological effectiveness (RBE) of 2.3-2.7 was obtained from the straight line obtained by modifying by the least squares method the frequency curves of malformed fetuses in total implants and in surviving fetuses. The types of malformations induced by Cf-252 and Co-60 irradiation were alike. Using fetal LD/sub 50/ as an index, 2.4 was obtained as RBE when irradiated on day 8 of pregnancy and 3.1 as that when irradiated on day 9. The results showed that Cf-252 had stronger a teratogenic effect than Co-60 gamma rays. (author).

  9. Dicty_cDB: SFB248 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFB248 (Link to dictyBase) - - - Contig-U11574-1 SFB248Z (Link... to Original site) - - SFB248Z 673 - - - - Show SFB248 Library SF (Link to library) Clone ID SFB248 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SF/SFB2-B/SFB248Q.Seq.d/ Representative seq. ID SFB24...8Z (Link to Original site) Representative DNA sequence >SFB248 (SFB248Q) /CSM/SF/SFB2-B/SFB248Q.Seq.d/ XXXXX...ate 2001. 6. 1 Translated Amino Acid sequence ---SDNVPLNTNEDGTEKKYSFYEVPYYRFLFNVDTKEVGLRLIRSMLPIKFSFFNLIRE N

  10. 7 CFR 248.9 - Nutrition education.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Nutrition education. 248.9 Section 248.9 Agriculture... Nutrition education. (a) Goals. Nutrition education shall emphasize the relationship of proper nutrition to.... (b) Requirement. The State agency shall integrate nutrition education into FMNP operations and...

  11. 7 CFR 248.12 - FMNP costs.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.12... associated with the provision of nutrition education which meets the requirements of § 248.9 of this part....

  12. Dicty_cDB: SSI248 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSI248 (Link to dictyBase) ssi248 G03117 DDB0231632 Contig-U16127-1 SSI2...48P (Link to Original site) SSI248F 606 SSI248Z 596 SSI248P 1202 - - Show SSI248 Library SS (Link ...to library) Clone ID SSI248 (Link to dictyBase) Atlas ID ssi248 NBRP ID G03117 dictyBase ID DDB0231632 Link ...to Contig Contig-U16127-1 Original site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SS/SSI2-B/SSI2...48Q.Seq.d/ Representative seq. ID SSI248P (Link to Original site) Representative DNA sequence >SSI248 (SSI2

  13. Dicty_cDB: SLC248 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLC248 (Link to dictyBase) - G20509 DDB0205993 Contig-U15319-1 | Contig-U15640-1 SLC2...48P (Link to Original site) SLC248F 663 SLC248Z 519 SLC248P 1182 - - Show SLC248 Libr...ary SL (Link to library) Clone ID SLC248 (Link to dictyBase) Atlas ID - NBRP ID G20509 dictyBase ID DDB02059...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC2-B/SLC248Q.Seq.d/ Representative seq. ID SLC248P (Link to Original site) ...Representative DNA sequence >SLC248 (SLC248Q) /CSM/SL/SLC2-B/SLC248Q.Seq.d/ GAAAAAAGAAGAAAAAGCTAAAATAAAAATCA

  14. 40 CFR 98.248 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.248 Definitions. Except as specified in this section... onsite. Product does not include process vent emissions, fugitive emissions, or wastewater....

  15. Apparatus for the measurement of total body nitrogen using prompt neutron activation analysis with californium-252.

    Science.gov (United States)

    Mackie, A; Hannan, W J; Smith, M A; Tothill, P

    1988-01-01

    Details of clinical apparatus designed for the measurement of total body nitrogen (as an indicator of body protein), suitable for the critically ill, intensive-care patient are presented. Californium-252 radio-isotopic neutron sources are used, enabling a nitrogen measurement by prompt neutron activation analysis to be made in 40 min with a precision of +/- 3.2% for a whole body dose equivalent of 0.145 mSv. The advantages of Californium-252 over alternative neutron sources are discussed. A comparison between two irradiation/detection geometries is made, leading to an explanation of the geometry adopted for the apparatus. The choice of construction and shielding materials to reduce the count rate at the detectors and consequently to reduce the pile-up contribution to the nitrogen background is discussed. Salient features of the gamma ray spectroscopy system to reduce spectral distortion from pulse pile-up are presented.

  16. 31 CFR 248.1 - Introductory.

    Science.gov (United States)

    2010-07-01

    ... FOREIGN COUNTRIES OR UNITED STATES TERRITORIES OR POSSESSIONS § 248.1 Introductory. This part governs the issuance of substitutes for checks of the United States drawn on United States dollar or foreign currency accounts, maintained with designated depositaries in foreign countries or territories or possessions of...

  17. 7 CFR 248.11 - Financial management system.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Financial management system. 248.11 Section 248.11... § 248.11 Financial management system. (a) Disclosure of expenditures. The State agency shall maintain a financial management system which provides accurate, current and complete disclosure of the financial...

  18. 7 CFR 58.248 - Nonfat dry milk.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Nonfat dry milk. 58.248 Section 58.248 Agriculture... Products Bearing Usda Official Identification § 58.248 Nonfat dry milk. (a) Nonfat dry milk in commercial....S. Standard Grade. (b) Regular nonfat dry milk in consumer size packages which bears an...

  19. 248nm silicon photoablation: Microstructuring basics

    Energy Technology Data Exchange (ETDEWEB)

    Poopalan, P.; Najamudin, S. H.; Wahab, Y.; Mazalan, M. [Advanced Multidisciplinary MEMS-Based Integrated Electronic NCER Centre of Excellent (AMBIENCE), School of Microelectronic Engineering, Universiti Malaysia Perlis, 02600 Arau, Perlis (Malaysia)

    2015-05-15

    248nm pulses from a KrF excimer laser was used to ablate a Si wafer in order to ascertain the laser pulse and energy effects for use as a microstructuring tool for MEMS fabrication. The laser pulses were varied between two different energy levels of 8mJ and 4mJ while the number of pulses for ablation was varied. The corresponding ablated depths were found to range between 11 µm and 49 µm, depending on the demagnified beam fluence.

  20. CD248 facilitates tumor growth via its cytoplasmic domain

    Directory of Open Access Journals (Sweden)

    Janssens Tom

    2011-05-01

    Full Text Available Abstract Background Stromal fibroblasts participate in the development of a permissive environment for tumor growth, yet molecular pathways to therapeutically target fibroblasts are poorly defined. CD248, also known as endosialin or tumor endothelial marker 1 (TEM1, is a transmembrane glycoprotein expressed on activated fibroblasts. We recently showed that the cytoplasmic domain of CD248 is important in facilitating an inflammatory response in a mouse model of arthritis. Others have reported that CD248 gene inactivation in mice results in dampened tumor growth. We hypothesized that the conserved cytoplasmic domain of CD248 is important in regulating tumor growth. Methods Mice lacking the cytoplasmic domain of CD248 (CD248CyD/CyD were generated and evaluated in tumor models, comparing the findings with wild-type mice (CD248WT/WT. Results As compared to the response in CD248WT/WT mice, growth of T241 fibrosarcomas and Lewis lung carcinomas was significantly reduced in CD248CyD/CyD mice. Tumor size was similar to that seen with CD248-deficient mice. Conditioned media from CD248CyD/CyD fibroblasts were less effective at supporting T241 fibrosarcoma cell survival. In addition to our previous observation of reduced release of activated matrix metalloproteinase (MMP-9, CD248CyD/CyD fibroblasts also had impaired PDGF-BB-induced migration and expressed higher transcripts of tumor suppressor factors, transgelin (SM22α, Hes and Hey1. Conclusions The multiple pathways regulated by the cytoplasmic domain of CD248 highlight its potential as a therapeutic target to treat cancer.

  1. 31 CFR 248.4 - Undertaking of indemnity.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Undertaking of indemnity. 248.4 Section 248.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... in the circumstances set forth below, a corporate surety authorized by the Secretary of the...

  2. 49 CFR 195.248 - Cover over buried pipeline.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Cover over buried pipeline. 195.248 Section 195.248 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION...

  3. 47 CFR 90.248 - Wildlife and ocean buoy tracking.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Wildlife and ocean buoy tracking. 90.248... SERVICES PRIVATE LAND MOBILE RADIO SERVICES Non-Voice and Other Specialized Operations § 90.248 Wildlife... tracking of, and the telemetry of scientific data from, ocean buoys and animal wildlife. (b)...

  4. 24 CFR 248.223 - Alternative State strategy.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Alternative State strategy. 248.223... Preservation Act of 1987 § 248.223 Alternative State strategy. (a) The Commissioner may approve a State strategy providing for State approval of plans of action that involve termination of low...

  5. 17 CFR 248.126 - Delivery of opt out notices.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.126 Delivery... electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts the notice on...

  6. Clinical Report on Californium-252 Neutron Intraluminal Brachytherapy Combined with External Irradiation for Cervical Carcinoma Treatment

    Institute of Scientific and Technical Information of China (English)

    Huanyu Zhao; Keming Wang; Jian Sun; Xin Geng; Weiming Zhang

    2006-01-01

    OBJECTIVE To observe the curative effects and complications of californium-252 (252Cf) neutron intraluminal brachytherapy (IBT) combined with external irradiation (El) for treatment of cervical carcinoma.METHODS From December 2000 to December 2004, 128 cases of cervical carcinoma staged into ⅡA~ⅢB according to the International Federation of Gynecology and Obstetrics (FIGO) standards were treated with 252Cf neutron IBT using 8~10 Gy per fraction, once a week. The total dose at reference A point was 36~40 Gy in 4~5 fractions. From the second day after 252Cf neutron IBT treatment, the whole pelvic cavity was treated with 60Co γ-ray El, applying 2 Gy per fraction, 4 times per week. After 20~25 Gy of El, the center of the whole pelvic field was blocked with 4 cm of lead in width. The total dose of El was 45~50 Gy.RESULTS The short-term therapeutic effects were CR 95.3% and PR 4.7%. The 3 and 5-year local control rates were 93.5% and 87.9%. The overall 3-year survival rate was 87.5% and for Stages Ⅱ and Ⅲ , 90.9%and 81.5% respectively; the overall 5-year survival rate was 70% and for Stages Ⅱ and Ⅲ, 76.2% and 61% respectively. The rate of radiation complications was 4.7% for radiation cystitis, 7.8% for radiation proctitis, 6.3%for vagina contracture and adhesion and 5.5% for protracted radiation proctitis.CONCLUSION An combination of 252Cf neutron IBT with El for treatment of cervical carcinoma can be well-tolerated by cervical carcinoma patients. The rate of local tumor control is high and radiation complications are few.

  7. Application of TSH bioindicator for studying the biological efficiency of neutrons from californium-252 source

    Energy Technology Data Exchange (ETDEWEB)

    Cebulska-Wasilewska, A.; Rekas, K. [Institute of Nuclear Physics, Cracow (Poland); Kim, J.K. [Korea Atomic Energy Research Inst., Taejon (Korea, Republic of)

    1997-12-31

    The effectiveness of neutrons from a Californium-252 source in the induction of various abnormalities in the Tradescantia clone 4430 stamen hair cells (TSH-assay) was studied. The special attention was paid to check whether any enhancement in effects caused by process of boron neutron capture is visible in the cells enriched with boron ions. Two chemicals (borax and BSH) were applied to introduce boron-10 ions into cells. Inflorescence, normal or pretreated with chemicals containing boron, were irradiated in the air with neutrons from a Cf-252 source at KAERI, Taejon, Korea. To estimate the relative biological effectiveness (RBE) in the induction of gene mutations of the neutron beam under the study, Tradescantia inflorescences, without any chemical pretreatment, were irradiated with various doses of X-rays. The ranges of radiation doses used were 0-0.1 Gy in neutrons and 0-0.5 Gy in X-rays. After the time needed to complete the postirradiation repair Tradescantia cuttings were transferred to Cracow, where screening of gene and lethal; mutations, cell cycle alterations in somatic cells have been done, and dose response relationships were figured. The maximal RBE values were estimated in the range of 4.6-6.8. Alterations of RBE value were observed; from 6.8 to 7.8 in the case of plants pretreated with 240 ppm of B-10 from borax, and 4.6 to 6.1 in the case of 400 ppm of B-10 from BSH. Results showed a slight, although statistically insignificant increase in biological efficacy of radiation from the Cf-252 source in samples pretreated with boron containing chemicals. (author)

  8. Study of the shielding for spontaneous fission sources of Californium-252; Estudio de blindaje para fuentes de fision espontanea de Californio-252

    Energy Technology Data Exchange (ETDEWEB)

    Davila R, I

    1991-06-15

    A shielding study is made to attenuate, until maximum permissible levels, the neutrons radiation and photons emitted by spontaneous fission coming from a source of Californium-252. The compound package by a database (Library DLC-23) and the ANISNW code is used, in it version for personal computer. (Author)

  9. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.124 Reasonable... affiliate to make marketing solicitations to a consumer about your products or services unless the consumer... Internet Web site at which the consumer has obtained a product or service. The consumer...

  10. 7 CFR 248.23 - Records and reports.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.23..., FMNP coupon issuance and redemption, equipment purchases and inventory, nutrition education, and...

  11. 7 CFR 248.1 - General purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... Special Supplemental Nutrition Program for Women, Infants and Children (WIC) or are on the waiting list... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1...

  12. 48 CFR 52.248-3 - Value Engineering-Construction.

    Science.gov (United States)

    2010-10-01

    ... end item's performance. (2) A list and analysis of the contract requirements that must be changed if... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Value Engineering....248-3 Value Engineering—Construction. As prescribed in 48.202, insert the following clause:...

  13. 17 CFR 248.127 - Renewal of opt out elections.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.127 Renewal of... expires, you may not make marketing solicitations to a consumer who previously opted out, unless: (i) The... description of the types of eligibility information that may be used to make marketing solicitations to...

  14. 48 CFR 52.248-1 - Value Engineering.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Value Engineering. 52.248... Value Engineering. As prescribed in 48.201, insert the following clause: Value Engineering (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit value engineering change...

  15. 42 CFR 403.248 - Administrative review of CMS determinations.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Administrative review of CMS determinations. 403... Certification Program: General Provisions § 403.248 Administrative review of CMS determinations. (a) This section provides for administrative review if CMS determines— (1) Not to certify a policy; or (2) That...

  16. 48 CFR 52.248-2 - Value Engineering-Architect-Engineer.

    Science.gov (United States)

    2010-10-01

    ...-Architect-Engineer. 52.248-2 Section 52.248-2 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.248-2 Value Engineering—Architect-Engineer. As prescribed in 48.201(f), insert the following clause: Value Engineering—Architect-Engineer (MAR 1990) (a) General. The Contractor shall (1)...

  17. 17 CFR 248.11 - Limits on redisclosure and reuse of information.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Limits on redisclosure and reuse of information. 248.11 Section 248.11 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Safeguarding Personal Information Limits on Disclosures § 248.11 Limits on redisclosure and reuse...

  18. Actinide production from xenon bombardments of curium-248

    Energy Technology Data Exchange (ETDEWEB)

    Welch, R.B.

    1985-01-01

    Production cross sections for many actinide nuclides formed in the reaction of /sup 129/Xe and /sup 132/Xe with /sup 248/Cm at bombarding energies slightly above the coulomb barrier were determined using radiochemical techniques to isolate these products. These results are compared with cross sections from a /sup 136/Xe + /sup 248/Cm reaction at a similar energy. When compared to the reaction with /sup 136/Xe, the maxima in the production cross section distributions from the more neutron deficient projectiles are shifted to smaller mass numbers, and the total cross section increases for the production of elements with atomic numbers greater than that of the target, and decreases for lighter elements. These results can be explained by use of a potential energy surface (PES) which illustrates the effect of the available energy on the transfer of nucleons and describes the evolution of the di-nuclear complex, an essential feature of deep-inelastic reactions (DIR), during the interaction. The other principal reaction mechanism is the quasi-elastic transfer (QE). Analysis of data from a similar set of reactions, /sup 129/Xe, /sup 132/Xe, and /sup 136/Xe with /sup 197/Au, aids in explaining the features of the Xe + Cm product distributions, which are additionally affected by the depletion of actinide product yields due to deexcitation by fission. The PES is shown to be a useful tool to predict the general features of product distributions from heavy ion reactions.

  19. Long-term effects of an intracavitary treatment with californium-252 on normal tissue. [Swine, /sup 226/Ra

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, M.F.; Beamer, J.L.; Mahony, T.D.; Cross, F.T.; Lund, J.E.; Endres, G.W.R.

    1976-01-01

    About one hundred fifty swine were exposed to either radium-226 or californium-252 sources in the uterine cervix to determine an RBE for both acute and long-term effects. That value for early changes in the tissues at risk in the treatment of cervical cancer was between 6.2 and 6.8. The incidence of complications increased with time after exposure, especially among animals treated with /sup 252/Cf. Analysis of rectal injury showed that ulceration occurred frequently within a year postexposure at doses between 1600 and 2400 rad calculated at 2 cm lateral to the source midline. Fat necrosis and smooth muscle atrophy, resulting in a local rectal stricture, were delayed changes observed in some animals. The lower ureter was the site for a greater frequency of complications than the GI tract. Ureteral stricture often occurred at doses of 1200 rad from /sup 252/Cf and 7000 rad from /sup 226/Ra. Observation of delayed effects in the uterine-cervix in animals held up to 4 years postexposure indicate that the RBE for /sup 252/Cf may be increased to a value as high as 18, while repair may have even decreased it to about 5.6 in the rectum. Fifty swine are still being observed for long-term effects after doses above 800 rad from /sup 252/Cf and 5000 rad from /sup 226/Ra.

  20. Development of electron beam ion source charge breeder for rare isotopes at Californium Rare Isotope Breeder Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Kondrashev, S.; Dickerson, C.; Levand, A.; Ostroumov, P. N.; Pardo, R. C.; Savard, G.; Vondrasek, R. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Alessi, J.; Beebe, E.; Pikin, A. [Collider-Accelerator Department, Brookhaven National Laboratory, Upton, New York 11973 (United States); Kuznetsov, G. I.; Batazova, M. A. [Budker Institute of Nuclear Physics, Novosibirsk 630090 (Russian Federation)

    2012-02-15

    Recently, the Californium Rare Isotope Breeder Upgrade (CARIBU) to the Argonne Tandem Linac Accelerator System (ATLAS) was commissioned and became available for production of rare isotopes. Currently, an electron cyclotron resonance ion source is used as a charge breeder for CARIBU beams. To further increase the intensity and improve the purity of neutron-rich ion beams accelerated by ATLAS, we are developing a high-efficiency charge breeder for CARIBU based on an electron beam ion source (EBIS). The CARIBU EBIS charge breeder will utilize the state-of-the-art EBIS technology recently developed at Brookhaven National Laboratory (BNL). The electron beam current density in the CARIBU EBIS trap will be significantly higher than that in existing operational charge-state breeders based on the EBIS concept. The design of the CARIBU EBIS charge breeder is nearly complete. Long-lead components of the EBIS such as a 6-T superconducting solenoid and an electron gun have been ordered with the delivery schedule in the fall of 2011. Measurements of expected breeding efficiency using the BNL Test EBIS have been performed using a Cs{sup +} surface ionization ion source for external injection in pulsed mode. In these experiments we have achieved {approx}70% injection/extraction efficiency and breeding efficiency into the most abundant charge state of {approx}17%.

  1. Development of electron beam ion source charge breeder for rare isotopes at Californium Rare Isotope Breeder Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Kondrashev S.; Alessi J.; Dickerson, C.; Levand, A.; Ostroumov, P.N.; Pardo, R.C.; Savard, G.; Vondrasek, R.; Beebe, E.; Pikin, A.; Kuznetsov, G.I.; Batazova, M.A.

    2012-02-03

    Recently, the Californium Rare Isotope Breeder Upgrade (CARIBU) to the Argonne Tandem Linac Accelerator System (ATLAS) was commissioned and became available for production of rare isotopes. Currently, an electron cyclotron resonance ion source is used as a charge breeder for CARIBU beams. To further increase the intensity and improve the purity of neutron-rich ion beams accelerated by ATLAS, we are developing a high-efficiency charge breeder for CARIBU based on an electron beam ion source (EBIS). The CARIBU EBIS charge breeder will utilize the state-of-the-art EBIS technology recently developed at Brookhaven National Laboratory (BNL). The electron beam current density in the CARIBU EBIS trap will be significantly higher than that in existing operational charge-state breeders based on the EBIS concept. The design of the CARIBU EBIS charge breeder is nearly complete. Long-lead components of the EBIS such as a 6-T superconducting solenoid and an electron gun have been ordered with the delivery schedule in the fall of 2011. Measurements of expected breeding efficiency using the BNL Test EBIS have been performed using a Cs{sup +} surface ionization ion source for external injection in pulsed mode. In these experiments we have achieved {approx}70% injection/extraction efficiency and breeding efficiency into the most abundant charge state of {approx}17%.

  2. 7 CFR 248.22 - Nonprocurement debarment/suspension, drug-free workplace, and lobbying restrictions.

    Science.gov (United States)

    2010-01-01

    ... workplace, and lobbying restrictions. 248.22 Section 248.22 Agriculture Regulations of the Department of.../suspension, drug-free workplace, and lobbying restrictions. The State agency shall ensure compliance with the... lobbying (7 CFR part 3018), where applicable....

  3. 17 CFR 248.12 - Limits on sharing account number information for marketing purposes.

    Science.gov (United States)

    2010-04-01

    ... number information for marketing purposes. 248.12 Section 248.12 Commodity and Securities Exchanges... account number information for marketing purposes. (a) General prohibition on disclosure of account..., direct mail marketing, or other marketing through electronic mail to the consumer. (b)...

  4. 17 CFR 248.13 - Exception to opt out requirements for service providers and joint marketing.

    Science.gov (United States)

    2010-04-01

    ... requirements for service providers and joint marketing. 248.13 Section 248.13 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of... out requirements for service providers and joint marketing. (a) General rule. (1) The opt...

  5. 24 CFR 248.111 - Appraisal and preservation value of eligible low income housing.

    Science.gov (United States)

    2010-04-01

    ... eligible low income housing. 248.111 Section 248.111 Housing and Urban Development Regulations Relating to... HOUSING ACT AND OTHER AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayments and Plans of Action Under the Low Income Housing Preservation and Resident Homeownership Act of 1990 §...

  6. 7 CFR 248.8 - Level of benefits and eligible foods.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Level of benefits and eligible foods. 248.8 Section... Benefits § 248.8 Level of benefits and eligible foods. (a) General. State agencies shall identify in the... limited to: honey, maple syrup, cider, nuts and seeds, eggs, cheese, meat and seafood. Locally grown...

  7. PHILIPS 248X3LFH 时尚和健康的完美组合

    Institute of Scientific and Technical Information of China (English)

    刘宗宇

    2012-01-01

    飞利浦MODA显示器248C3LSB依靠时尚的造型和优秀的显示效果获得了《微型计算机》编辑部年度推荐产品称号。而现在,飞利浦新推出了一款可以称之为MODA升级版的248x3LFH显示器。

  8. The preparation of 248CmF 3 deposits on self-supported carbon foils

    Science.gov (United States)

    Aaron, W. S.; Petek, M.; Zevenbergen, L. A.

    1987-06-01

    Another target preparative technique was recently added to the Isotope Research Materials Laboratory's (IRML) capabilities for custom target fabrication. In support of super-heavy-ion physics experiments, methods and equipment were developed for the preparation of 248CmF 3 deposits on carbon foils. The starting material was obtained as either a chloride or nitrate solution, converted to the flouride, and evaporated on carbon foil substrates. Deposits ranging from 40 to 570 μg/cm 2 were prepared as a 12-mm-diam spot on 45- to 60-μg/cm 2 self-supported carbon foils. The deposits were then overcoated with approximately 10 μg/cm 2 of carbon to minimize contamination problems during target handling. The high cost of 248Cm ($100/μg) and its limited availability were the key constraints in the development of preparative technology beyond the inherent radioactivity of 248Cm.

  9. Chalcogenide compounds made by pulsed laser deposition at 355 and 248 nm

    DEFF Research Database (Denmark)

    Ettlinger, Rebecca Bolt; Cazzaniga, Andrea Carlo; Crovetto, Andrea;

    Thin films made by pulsed laser deposition may differ depending on the laser wavelength. We compared ZnS, Cu2SnS3 and a target enriched with SnS relative to Cu2SnS3 using 355 nm and 248 nm lasers......Thin films made by pulsed laser deposition may differ depending on the laser wavelength. We compared ZnS, Cu2SnS3 and a target enriched with SnS relative to Cu2SnS3 using 355 nm and 248 nm lasers...

  10. 19 CFR 10.248 - Additional requirements for preferential treatment of brassieres.

    Science.gov (United States)

    2010-04-01

    .... Andean Trade Promotion and Drug Eradication Act Apparel and Other Textile Articles Under the Andean Trade Promotion and Drug Eradication Act § 10.248 Additional requirements for preferential treatment of brassieres... United States means: (i) The price of the fabrics when last purchased, f.o.b. port of exportation, as...

  11. 29 CFR 779.248 - Purchase or receive “goods for resale.”

    Science.gov (United States)

    2010-07-01

    ... section 3(s)(1) of the prior Act if they are purchased or received with the intention of being resold... purchased or received by the enterprise with the intention of reselling them in the same form or after... 29 Labor 3 2010-07-01 2010-07-01 false Purchase or receive âgoods for resale.â 779.248 Section...

  12. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Science.gov (United States)

    2010-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.125... consumer that you receive from an affiliate to make a marketing solicitation to the consumer about your... electronically mailed or processed at an Internet Web site, if the consumer agrees to the electronic delivery...

  13. 17 CFR 248.122 - Scope and duration of opt out.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.122 Scope and... information received from another affiliate as described in the notice to make marketing solicitations to the... the expectation of engaging in other transactions. (4) Menu of alternatives. A consumer may be...

  14. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Science.gov (United States)

    2010-04-01

    ... EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt out...”; (iii) A general description of the types of eligibility information that may be used to make...

  15. 12 CFR 303.248 - Truth in Lending Act-Relief from reimbursement.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Truth in Lending Act-Relief from reimbursement... PRACTICE FILING PROCEDURES Other Filings § 303.248 Truth in Lending Act—Relief from reimbursement. (a) Scope. This section applies to requests for relief from reimbursement pursuant to the Truth in...

  16. 24 CFR 248.153 - Incentives to extend low income use.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Incentives to extend low income use... AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayments and Plans of Action Under the Low Income Housing Preservation and Resident Homeownership Act of 1990 § 248.153 Incentives to extend low income...

  17. 24 CFR 248.231 - Incentives to extend low income use.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Incentives to extend low income use... AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayment and Plans of Action Under the Emergency Low Income Preservation Act of 1987 § 248.231 Incentives to extend low income use. The Commissioner may...

  18. P53 codon 11, 72, and 248 gene polymorphisms in endometriosis

    Directory of Open Access Journals (Sweden)

    Yao-Yuan Hsieh , Chich-Sheng Lin

    2006-01-01

    Full Text Available Objective: Mutated p53 gene is related to the instability of cell growth and cell cycle progression. We aimed to evaluate the association between endometriosis and p53 codon 11, 72 and 248 gene polymorphisms. Patients and methods: Women were divided into two groups: (1 moderate/severe endometriosis (n=148, and (2 non-endometriosis groups (n=150. P53 gene polymorphisms include codon11 Glu/Gln or Lys (GAG->CAG or AAG, codon 72 Arg/Pro (CGC->CCC, and codon 248 Arg/Thr (CGG->TCG. These gene polymorphisms were amplified by polymerase chain reaction and detected by electrophoresis after restriction enzyme (Taq I, BstU I, Hap II digestions. Associations between the endometriosis and p53 polymorphisms were evaluated. Results: The distributions of p53 codon 72 polymorphisms in both groups were significantly different. The proportions of Arg homozygotes/heterozygotes/Pro homozygotes in both groups were 9.5/66.2/24.3% and 30.7/50/19.3%. The proportions of Arg/Pro alleles were 42.6/57.4% and 56/44%. The distributions of p53 codon 11 and 248 polymorphisms in both groups were non-significantly different. All individuals appeared the wild genotypes (Glu11 and Arg248 homozygotes. Conclusion: Association between endometriosis and p53 codon 72 polymorphism exists. P53 codon 72*Pro-related genotype and allele are related with higher susceptibility of endometriosis. P53 codon 11 and 248 polymorphisms are not related with endometriosis susceptibility.

  19. 30 CFR 250.248 - What solid and liquid wastes and discharges information and cooling water intake information must...

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What solid and liquid wastes and discharges information and cooling water intake information must accompany the DPP or DOCD? 250.248 Section 250.248 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL...

  20. PCR-RFLP to Detect Codon 248 Mutation in Exon 7 of "p53" Tumor Suppressor Gene

    Science.gov (United States)

    Ouyang, Liming; Ge, Chongtao; Wu, Haizhen; Li, Suxia; Zhang, Huizhan

    2009-01-01

    Individual genome DNA was extracted fast from oral swab and followed up with PCR specific for codon 248 of "p53" tumor suppressor gene. "Msp"I restriction mapping showed the G-C mutation in codon 248, which closely relates to cancer susceptibility. Students learn the concepts, detection techniques, and research significance of point mutations or…

  1. 17 CFR 248.30 - Procedures to safeguard customer records and information; disposal of consumer report information.

    Science.gov (United States)

    2010-04-01

    ... customer records and information; disposal of consumer report information. 248.30 Section 248.30 Commodity... of consumer report information. (a) Every broker, dealer, and investment company, and every... any customer. (b) Disposal of consumer report information and records—(1) Definitions (i)...

  2. A temperature supervisory system based on PIC18F248%基于PIC18F248的温度监控系统的研究

    Institute of Scientific and Technical Information of China (English)

    王欣欣; 高勇伟

    2008-01-01

    为了监控大电流磁体电源的温度变化,采用微处理器PIC18F248进行实时监控.首先设计传感器DS18B20的调理电路,通过添加共模抑制线圈提高系统的抗干扰能力,然后利用CAN总线完成多路多点的数据采集,最后采用LabVIEW驱动CAN接口卡并设计系统接收界面.

  3. Study on damage of K9 glass under 248nm ultraviolet pulsed laser irradiation

    Science.gov (United States)

    Wang, Xi; Fang, Xiaodong

    2015-04-01

    The damage of K9 glass under 248nm ultraviolet pulsed laser irradiation was studied. The laser pulse energy was kept within the range of 60mJ to 160mJ, and the repetition rate was adjusted within the range of 1Hz to 40Hz. The damage morphologies of single-pulse and multi-pulse laser irradiation were characterized by optical microscope, and the damage mechanism was discussed. The experimental results indicated that the damage of K9 glass irradiated by 248nm ultraviolet laser mainly followed the thermal-mechanical coupling mechanism and the damage threshold of K9 glass was 2.8J/cm2. The intensity of damage area increased gradually with the increase of the laser pulse number. It was shown that accumulation effect of laser induced damage to K9 glass was obvious.

  4. Unveiling the structure of the planetary nebula M 2-48 Kinematics and physical conditions

    CERN Document Server

    López-Martin, L; Esteban, C; Vázquez, R; Raga, A C; Torrelles, J M; Miranda, L F; Meaburn, J; Olguin, L

    2002-01-01

    The kinematics and physical conditions of the bipolar planetary nebula M 2-48 are analysed from high and low dispersion long-slit spectra. Previous CCD narrow-band optical observations have suggested that this nebula is mainly formed by a pair of symmetric bow-shocks, an off-center semi-circular shell, and an internal bipolar structure. The bipolar outflow has a complex structure, characterised by a series of shocked regions located between the bright core and the polar tips. There is an apparent kinematic discontinuity between the bright bipolar core and the outer regions. The fragmented ring around the bright bipolar region presents a low expansion velocity and could be associated to ejection in the AGB-PN transition phase, although its nature remains unclear. The chemical abundances of the central region are derived, showing that M 2-48 is a Type I planetary nebula (PN).

  5. Actinide Production in the Reaction of Heavy Ions withCurium-248

    Energy Technology Data Exchange (ETDEWEB)

    Moody, K.J.

    1983-07-01

    Chemical experiments were performed to examine the usefulness of heavy ion transfer reactions in producing new, neutron-rich actinide nuclides. A general quasi-elastic to deep-inelastic mechanism is proposed, and the utility of this method as opposed to other methods (e.g. complete fusion) is discussed. The relative merits of various techniques of actinide target synthesis are discussed. A description is given of a target system designed to remove the large amounts of heat generated by the passage of a heavy ion beam through matter, thereby maximizing the beam intensity which can be safely used in an experiment. Also described is a general separation scheme for the actinide elements from protactinium (Z = 91) to mendelevium (Z = 101), and fast specific procedures for plutonium, americium and berkelium. The cross sections for the production of several nuclides from the bombardment of {sup 248}Cm with {sup 18}O, {sup 86}Kr and {sup 136}Xe projectiles at several energies near and below the Coulomb barrier were determined. The results are compared with yields from {sup 48}Ca and {sup 238}U bombardments of {sup 248}Cm. Simple extrapolation of the product yields into unknown regions of charge and mass indicates that the use of heavy ion transfer reactions to produce new, neutron-rich above-target species is limited. The substantial production of neutron-rich below-target species, however, indicates that with very heavy ions like {sup 136}Xe and {sup 238}U the new species {sup 248}Am, {sup 249}Am and {sup 247}Pu should be produced with large cross sections from a {sup 248}Cm target. A preliminary, unsuccessful attempt to isolate {sup 247}Pu is outlined. The failure is probably due to the half life of the decay, which is calculated to be less than 3 minutes. The absolute gamma ray intensities from {sup 251}Bk decay, necessary for calculating the {sup 251}Bk cross section, are also determined.

  6. 42 CFR 137.248 - What effect will a retrocession have on a retroceding Self-Governance Tribe's rights to contract...

    Science.gov (United States)

    2010-10-01

    ... Tribe may request; and (c) Any future request by such Self-Governance Tribe or an Indian Tribe to... retroceding Self-Governance Tribe's rights to contract or compact under the Act? 137.248 Section 137.248..., DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.248 What effect will...

  7. Ion imaging studies of the photodissociation dynamics of CH2I2 at 248 nm

    Science.gov (United States)

    Lehman, Julia H.; Li, Hongwei; Lester, Marsha I.

    2013-12-01

    The photodissociation of CH2I2 at 248 nm is investigated using velocity map ion imaging with photoionization detection of the I∗ (2P1/2) products. The velocity distribution of the I∗ products reveals that only a small fraction of the available energy is released as translational energy, consistent with a simple impulsive model. Most of the excess energy is channeled into internal excitation with = 36.3 kcal mol-1 for CH2I radical fragments produced with I∗ atoms. The anisotropy angular distribution of the I∗ fragments and corresponding positive anisotropy parameter are indicative of prompt dissociation and electronic state mixing.

  8. 自然周期IVF-ET 248例临床分析%Clinical analysis of 248 cases with natural cycle IVF-ET

    Institute of Scientific and Technical Information of China (English)

    唐莉; 马艳萍; 章晓梅; 李勇刚; 高显琼

    2009-01-01

    目的:探讨自然周期体外受精-胚胎移植(NC-IVF-ET)技术在不孕症治疗中的临床应用价值.方法:采用SPSS统计软件包对248例行NC-IVF-ET和2 185例行控制性超排卵(短方案COH)助孕的患者促排卵结果进行分析.结果:NC-IVF-ET组的获卵率和临床妊娠率显著低于COH组(P0.05).而NC-IVF-ET组的OHSS发生率和多胎妊娠率则显著低于COH组(P<0.05).在各种原因引起的不孕症中,输卵管因素引起的不孕症临床妊娠率最高,而无获卵是最主要的取消原因.结论:NC-IVF-ET不使用促排卵药物,经济、安全,应在有适应证的不孕症患者中加以应用.

  9. A bright-rimmed cloud sculpted by the H ii region Sh2-48

    CERN Document Server

    Ortega, M E; Giacani, E; Rubio, M; Dubner, G

    2013-01-01

    To characterize a bright-rimmed cloud embedded in the HII region Sh2-48 searching for evidence of triggered star formation. We carried out observations towards a region of 2'x2' centered at RA=18h 22m 11.39s, dec.=-14deg 35m 24.81s (J2000) using the Atacama Submillimeter Telescope Experiment (ASTE; Chile) in the 12CO J=3-2,13CO J=3-2, HCO+ J=4-3, and CS J=7-6 lines with an angular resolution of about 22". We also present radio continuum observations at 5 GHz carried out with the Jansky Very Large Array (JVLA; EEUU) interferometer with a synthetized beam of 7"x5". The analysis of our molecular observations reveals the presence of a relatively dense clump with n(H_2)~3x10^3 cm^-3, located in projection onto the interior of the HII region Sh2-48. The emission distribution of the four observed molecular transitions has, at VLSR~38 kms^-1, morphological anti-correlation with the bright-rimmed cloud as seen in the optical emission. From the new radio continuum observations we identify a thin layer of ionized gas lo...

  10. Stability of {sup 248–254}Cf isotopes against alpha and cluster radioactivity

    Energy Technology Data Exchange (ETDEWEB)

    Santhosh, K.P., E-mail: drkpsanthosh@gmail.com; Biju, R.K.

    2013-07-15

    Stability of {sup 248–254}Cf nuclei against alpha and cluster emissions is studied within our Coulomb and proximity potential model (CPPM). It is found that these nuclei are stable against light clusters (except alpha particles) and unstable against heavy cluster (A{sub 2}≥40) emissions. For heavy cluster emissions the daughter nuclei lead to doubly magic {sup 208}Pb or the neighbouring one. The effects of quadrupole and hexadecapole deformations of parent nuclei, daughter nuclei and emitted cluster on half lives are also studied. The computed alpha decay half life values (including quadrupole deformation β{sub 2}) are in close agreement with experimental data. Inclusion of quadrupole deformation reduces the height and width of the barrier (increases the barrier penetrability) and hence half life decreases. -- Highlights: •{sup 248–254}Cf parents are stable against light clusters (except alpha particles) and are unstable against heavy clusters ({sup 46}Ar, {sup 48,50}Ca etc.). •For the case of heavy cluster emissions the daughter nuclei are doubly magic {sup 208}Pb or neighbouring one. •The alpha decay half lives are in agreement with experimental data. •The cluster decay half lives decrease with the inclusion of quadrupole deformation.

  11. Stability of 248-254^Cf isotopes against alpha and cluster radioactivity

    CERN Document Server

    Santhosh, K P

    2013-01-01

    Stability of 248-254^Cf nuclei against alpha and cluster emission is studied within our Coulomb and proximity potential model (CPPM). It is found that these nuclei are stable against light clusters (except alpha particle) and instable against heavy cluster emissions. For heavy cluster emissions the daughter nuclei lead to doubly magic 208^Pb or neighbouring one. The effect of quadrapole and hexadecapole deformations of parent nuclei, daughter nuclei and emitted cluster on half lives are also studied. The computed alpha decay half life values (with including quadrupole deformation {\\beta}2) are in close agreement with experimental data. Inclusion of quadrupole deformation reduces the height and width of the barrier (increases the barrier penetrability) and hence half life decreases.

  12. Half-life and inner penetrability in the cold fission of {sup 248}Cm

    Energy Technology Data Exchange (ETDEWEB)

    Kunhikrishnan, P.V. [Sree Narayana College, Department of Physics, Kannur (India); Santhosh, K.P. [Kannur University, School of Pure and Applied Physics, Payyanur (India); Joseph, Antony [University of Calicut, Department of Physics, Malappuram, Kerala (India)

    2012-06-15

    Using the Coulomb and proximity potential model (CPPM) with the nuclear surface tension improved by Reisdorf, the various fragmentations in the cold fission of {sup 248}Cm are studied as a cluster decay process within a fission model. The computed half-life values are compared with the values reported by Sandulescu et al. using the double-folding M3Y nuclear-nuclear potential model and are in agreement with CPPM values. The diffuseness width used in the proximity potential is found to be sensitive to the half-life. The inner penetrability is computed based on the formalism of Poenaru et al. (J. Phys. G: Nucl. Part. Phys. 17, 443 (1991)) and found that in the cold fission the contribution of the inner part (overlap region) of the barrier is significant compared to cluster decays. The variation of the inner penetrability with fragment mass is studied which emphasizes the fact that cold fission is an extension of cluster decay. (orig.)

  13. Photosensitivity of ion-exchanged Er-doped phosphate glass using 248nm excimer laser radiation.

    Science.gov (United States)

    Pissadakis, Stavros; Ikiades, Aris; Hua, Ping; Sheridan, Anna; Wilkinson, James

    2004-07-12

    The photosensitivity to 248nm excimer laser radiation of Er-doped Schott IOG-1 phosphate glass is presented. The photosensitive mechanism is investigated by employing a grating recording process. Index changes of up to ~2.0x10(-3) were measured in silver ion-exchanged samples using diffraction efficiency measurements; whereas changes of only ~10(-5) were measured for non-ion-exchanged samples. Absorption measurements allowed the identification of specific color center bands, which were attributed to the glass matrix and to the silver ions. Investigation of the exposed ion-exchanged glass using scanning electron microscopy and energy dispersive x-ray microanalysis revealed that in addition to the color centers formed, silver ion migration and ionization contribute significantly to the UV-induced index changes.

  14. 清新护眼 飞利浦睿蓝摩登248X3LFH登场

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    飞利浦将创新的睿蓝光波(LightFrame)与Moda摩登系列产品完美结合,为用户带来最新力作——睿蓝摩登248X3LFH!与其它Moda产品不同的是248X3LFH机身背部采用了黑色镜面烤漆,而机身框架则采用极具金属质感的镀银处理,这样搭配圆润的铝铸基座,

  15. The research progress of metrological 248nm deep ultraviolent microscope inspection device

    Science.gov (United States)

    Wang, Zhi-xin; Li, Qi; Gao, Si-tian; Shi, Yu-shu; Li, Wei; Li, Shi

    2016-01-01

    In lithography process, the precision of wafer pattern to a large extent depends on the geometric dimensioning and tolerance of photomasks when accuracy of lithography aligner is certain. Since the minimum linewidth (Critical Dimension) of the aligner exposing shrinks to a few tens of nanometers in size, one-tenth of tolerance errors in fabrication may lead to microchip function failure, so it is very important to calibrate these errors of photomasks. Among different error measurement instruments, deep ultraviolent (DUV) microscope because of its high resolution, as well as its advantages compared to scanning probe microscope restrained by measuring range and scanning electron microscope restrained by vacuum environment, makes itself the most suitable apparatus. But currently there is very few DUV microscope adopting 248nm optical system, means it can attain 80nm resolution; furthermore, there is almost no DUV microscope possessing traceable calibration capability. For these reason, the National Institute of Metrology, China is developing a metrological 248nm DUV microscope mainly consists of DUV microscopic components, PZT and air supporting stages as well as interferometer calibration framework. In DUV microscopic component, the Köhler high aperture transmit condenser, DUV splitting optical elements and PMT pinhole scanning elements are built. In PZT and air supporting stages, a novel PZT actuating flexural hinge stage nested separate X, Y direction kinematics and a friction wheel driving long range air supporting stage are researched. In interferometer framework, a heterodyne multi-pass interferometer measures XY axis translation and Z axis rotation through Zerodur mirror mounted on stage. It is expected the apparatus has the capability to calibrate one dimensional linewidths and two dimensional pitches ranging from 200nm to 50μm with expanded uncertainty below 20nm.

  16. A systematic study of actinide production from the interactions of heavy ions with sup 248 Cm

    Energy Technology Data Exchange (ETDEWEB)

    Leyba, J.D.

    1990-09-07

    Production cross sections for heavy actinides produced from the interactions of {sup 12}C, {sup 31}P, {sup 40}Ar, and {sup 44}Ca ions with {sup 248}Cm were measured at energies ranging from 0.98 to 1.35 X Coulomb barrier. The recoiling reaction products were collected in copper or gold catcher foils located near the {sup 248}Cm target. Separate fractions of Bk, Cf, Es, Fm, and Md were obtained from a radiochemical separation procedure. For the {sup 12}C system, a He/KCl jet was used to transport the recoiling No activities of interest to a rotating wheel system. The isotopic distributions of the actinide products were found to be essentially symmetric about the maximum with full-widths-at-half-maximum of approximately 2.5 mass units. Isotopic distributions of the {sup 12}C, {sup 31}P, {sup 40}Ar, and {sup 44}Ca systems were found to be very similar to the {sup 40,48}Ca systems studied previously. The maxima of the isotopic distributions generally occurred for those reaction channels which involved the exchange of the fewest number of nucleons between the target and projectile for which the calculated excitation energy was a positive quantity. Additionally, the maxima of the excitation functions occurred at those projectile energies which were consistent with the calculated reaction barriers based upon a binary reaction mechanism. The experimental data from the four systems investigated were compared to several models of heavy ion interactions including a damped reaction mechanism, compound nucleus formation and subsequent particle evaporation, and classical partial wave calculations for binary systems.

  17. Californium Recovery from Palladium Wire

    Energy Technology Data Exchange (ETDEWEB)

    Burns, Jon D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2014-08-01

    The recovery of 252Cf from palladium-252Cf cermet wires was investigated to determine the feasibility of implementing it into the cermet wire production operation at Oak Ridge National Laboratory’s Radiochemical Engineering Development Center. The dissolution of Pd wire in 8 M HNO3 and trace amounts of HCl was studied at both ambient and elevated temperatures. These studies showed that it took days to dissolve the wire at ambient temperature and only 2 hours at 60°C. Adjusting the ratio of the volume of solvent to the mass of the wire segment showed little change in the kinetics of dissolution, which ranged from 0.176 mL/mg down to 0.019 mL/mg. A successful chromatographic separation of 153Gd, a surrogate for 252Cf, from Pd was demonstrated using AG 50x8 cation exchange resin with a bed volume of 0.5 mL and an internal diameter of 0.8 cm.

  18. Actinide production from the interactions of sup 40 Ca and sup 44 Ca with sup 248 Cm and a comparison with the sup 48 Ca+ sup 248 Cm system

    Energy Technology Data Exchange (ETDEWEB)

    Tuerler, A.; von Gunten, H.R. (Laboratorium fuer Radiochemie, Universitaet Bern, 3000 Bern 9 (Switzerland)); Leyba, J.D.; Hoffman, D.C.; Lee, D.M.; Gregorich, K.E.; Bennett, D.A.; Chasteler, R.M.; Gannett, C.M.; Hall, H.L.; Henderson, R.A.; Nurmia, M.J. (Nuclear Science Division, Lawrence Berkeley Laboratory, Berkeley, California 94720 (United States))

    1992-10-01

    Excitation functions have been measured for production of isotopes of Th through Fm in bombardments of {sup 248}Cm with 231- to 323-MeV {sup 44}Ca ions and for the production of isotopes of Th through Cm in bombardments of {sup 248}Cm with 230- to 291-MeV {sup 40}Ca ions, respectively, using radiochemical methods. Upper production cross section limits were established for nuclides that were not positively detected. The experimental data were compared with the results of previous reaction studies in the systems {sup 40}Ca+{sup 248}Cm and {sup 48}Ca+{sup 248}Cm. The half-widths of the Gaussian isotopic distributions were about 2.5 mass numbers for above-target elements and 5 to 5.5 mass numbers for below-target elements in all three systems. The majority of the cross section for the production of above-target nuclides was assigned to predominantly quasielastic reactions, whereas below-target nuclides were formed in deeply inelastic and asymmetric quasifission reactions. The maxima of the isotopic distributions were shown by others to closely follow the minimum of the potential energy surface in experiments with {sup 48}Ca, whereas in reactions with {sup 40}Ca and {sup 44}Ca we found that a transfer of 4 to 5 protons in either direction was required to reach the minimum in potential energy.

  19. 药物性肝病248例临床分析%Clinical analysis of 248 cases of drug induced liver diseases

    Institute of Scientific and Technical Information of China (English)

    杨立新

    2012-01-01

    Objective To explore the etiology, clinical features and prognosis of drug-induced liver disease (DILD). Methods A retrospective analysis was taken of DILD in hospitalized for medication history, clinical manifestations. Results The causes of DILD were mainly antibiotics (12. 1% ), medicine (23.0% ), anti-TB drugs (8.0% ), anti-cancer drugs (7. 2%), immunosuppressive agents (14..5%). The clinical manifestations were mainly anorexia (62.5%), fatigue (55. 1%), nausea (51.3%), jaundice (37.2%), abdominal pain (18.3%), pruritus (12.9% ), rash (4.6% ). Conclusion Clinicians should pay attention to and strengthen the DILD prevention, diagnosis and treatment.%目的 分析药物性肝病( DILD)的病因、临床特点及预后,提高临床医生对DILD的诊疗水平.方法 采用回顾性分析的方法对248例DILD住院患者的用药史、临床表现以及预后等进行研究.结果 引起DILD的药物以抗生素类药物(12.1%)、中药(23.0%)、抗结核药物(8.0%)、抗肿瘤药物(7.2%)、免疫抑制剂(14.5%)为常见.临床表现以纳差(62.5%)、乏力(55.1%)、恶心(51.3%)、黄疸(37.2%)、腹痛(18.3%)、瘙痒(12.9%)、皮疹(4.6%)等多见;肝性脑病、腹水、凝血酶原时间、黄疸等因素与患者死亡相关.结论 临床医生应重视和加强DILD的预防、诊断和治疗.

  20. A superburst candidate in EXO 1745--248 as a challenge to thermonuclear ignition models

    CERN Document Server

    Altamirano, D; Cumming, A; Sivakoff, G R; Heinke, C O; Wijnands, R; Degenaar, N; Homan, J; Pooley, D

    2012-01-01

    We report on Chandra, RXTE, Swift/BAT and MAXI observations of a ~1 day X-ray flare and subsequent outburst of a transient X-ray source observed in October-November 2011 in the globular cluster Terzan 5. We show that the source is the same as the transient that was active in 2000, i.e., the neutron star low-mass X-ray binary EXO 1745-248. For the X-ray flare we estimate a 6-11 hr exponential decay time and a radiated energy of 2-9 x 10^42 erg. These properties, together with strong evidence of decreasing blackbody temperature during the flare decay, are fully consistent with what is expected for a thermonuclear superburst. We use the most recent superburst models and estimate an ignition column depth of ~10^12 g cm^-2 and an energy release between 0.1-2 x 10^18 erg g^-1, also consistent with expected superburst values. We conclude therefore that the flare was most probably a superburst. We discuss our results in the context of theoretical models and find that even when assuming a few days of low level accreti...

  1. SN Hunt 248: a super-Eddington outburst from a massive cool hypergiant

    CERN Document Server

    Mauerhan, Jon C; Graham, Melissa L; Zheng, WeiKang; Clubb, Kelsey I; Filippenko, Alexei V; Valenti, Stefano; Brown, Peter J; Smith, Nathan; Howell, D Andrew; Arcavi, Iair

    2014-01-01

    We present photometric and spectroscopic observations of SN Hunt 248, a new supernova (SN) impostor in NGC 5806, which experienced a multi-stage outburst in May-June 2014. The initial "2014a" brightening that led to this object's discovery began with an absolute magnitude of -12, at which point the source exhibited the characteristics of a cool dense outflow, having a spectrum dominated by P-Cygni lines of Fe II, H I, and Na I, as well as strong line blanketing from metals (at the blue end). After two weeks of slow incline, the source rapidly climbed and peaked near M=-15 mag after two more weeks. During this bright "2014b" phase the source radiated a total energy of ~10^49 ergs, while the spectrum became dominated by Balmer emission and a stronger blue continuum, similar in appearance to the SN impostor SN 1997bs. Archival images of the host galaxy from the Hubble Space Telescope between 1997 and 2005 have revealed a luminous and variable precursor star. Its location on the HR diagram is consistent with a ma...

  2. Multiwavelength behaviour of the blazar OJ 248 from radio to {\\gamma}-rays

    CERN Document Server

    Carnerero, M I; Villata, M; Acosta-Pulido, J A; D'Ammando, F; Smith, P S; Larionov, V M

    2015-01-01

    We present an analysis of the multiwavelength behaviour of the blazar OJ 248 at z = 0.939 in the period 2006-2013. We use low-energy data (optical, near-infrared, and radio) obtained by 21 observatories participating in the GLAST-AGILE Support Program (GASP) of the Whole Earth Blazar Telescope (WEBT), as well as data from the Swift (optical-UV and X-rays) and Fermi (gamma-rays) satellites, to study flux and spectral variability and correlations among emissions in different bands. We take into account the effect of absorption by the Damped Lyman Alpha intervening system at z = 0.525. Two major outbursts were observed in 2006-2007 and in 2012-2013 at optical and near-IR wavelengths, while in the high-frequency radio light curves prominent radio outbursts are visible peaking at the end of 2010 and beginning of 2013, revealing a complex radio-optical correlation. Cross-correlation analysis suggests a delay of the optical variations after the gamma-ray ones of about a month, which is a peculiar behaviour in blazar...

  3. Cold valleys in the radioactive decay of 248-254Cf isotopes

    Indian Academy of Sciences (India)

    R K Biju; Sabina Sahadevan; K P Santosh; Antony Joseph

    2008-04-01

    Based on the concept of cold valley in cold fission and fusion, we have investigated the cluster decay process in 248-254Cf isotopes. In addition to alpha particle minima, other deep minima occur for S, Ar and Ca clusters. It is found that inclusion of proximity potential does not change the position of minima but minima become deeper. Taking Coulomb and proximity potential as interacting barrier for post-scission region, we computed half-lives and other characteristics for various clusters from these parents. Our study reveals that these parents are stable against light clusters and unstable against heavy clusters. Computed half-lives for alpha decay agree with experimental values within two orders of magnitude. The most probable clusters from these parents are predicted to be 46Ar, 48,50Ca which indicate the role of doubly or near doubly magic clusters in cluster radioactivity. Odd A clusters are found to be favorable for emission from odd A parents. Cluster decay model is extended to symmetric region and it is found that symmetric fission is also probable which stresses the role of doubly or near doubly magic 132Sn nuclei. Geiger-Nuttal plots were studied for various clusters and are found to be linear with varying slopes and intercepts.

  4. A COMPACT GROUP OF GALAXIES AT Z = 2.48 HOSTING AN AGN-DRIVEN OUTFLOW

    Energy Technology Data Exchange (ETDEWEB)

    Shih, Hsin-Yi [Gemini Observatory, 670 N Aohoku Place, Hilo, HI 96720 (United States); Stockton, Alan, E-mail: jshih@gemini.edu, E-mail: stockton@ifa.hawaii.edu [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States)

    2015-12-10

    We present observations of a remarkable compact group of galaxies at z = 2.48. Four galaxies, all within 40 kpc of each other, surround a powerful high-redshift radio source. This group comprises two compact red passive galaxies and a pair of merging galaxies. One of the red galaxies, with an apparent stellar mass of 3.6 × 10{sup 11}M{sub ⊙} and an effective radius of 470 pc, is one of the most extreme examples of a massive quiescent compact galaxy found so far. One of the pair of merging galaxies hosts the active galactic nucleus (AGN) producing the large powerful radio structure. The merger is massive and enriched, consistent with the mass–metallicity relation expected at this redshift. Close to the merging nuclei, the emission lines exhibit broad and asymmetric profiles that suggest outflows powered either by a very young expanding radio jet or by AGN radiation. At ≳50 kpc from the system, we found a fainter extended-emission region that may be a part of a radio-jet-driven outflow.

  5. Photodissociation of the Propargyl (C3D3) Radicals at 248 nm and 193 nm

    Energy Technology Data Exchange (ETDEWEB)

    Neumark., D.M.; Crider, P.E.; Castiglioni, L.; Kautzman, K.K.

    2009-01-21

    The photodissociation of perdeuterated propargyl (D{sub 2}CCCD) and propynyl (D{sub 3}CCC) radicals was investigated using fast beam photofragment translational spectroscopy. Radicals were produced from their respective anions by photodetachment at 540 nm and 450 nm (below and above the electron affinity of propynyl). The radicals were then photodissociated by 248 nm or 193 nm light. The recoiling photofragments were detected in coincidence with a time- and position-sensitive detector. Three channels were observed: D{sub 2} loss, CD + C{sub 2}D{sub 2}, and CD{sub 3} + C{sub 2}. Obervation of the D loss channel was incompatible with this experiment and was not attempted. Our translational energy distributions for D{sub 2} loss peaked at nonzero translational energy, consistent with ground state dissociation over small (< 1 eV) exit barriers with respect to separated products. Translational energy distributions for the two heavy channels peaked near zero kinetic energy, indicating dissociation on the ground state in the absence of exit barriers.

  6. 248-nm photolithography compatibility on low-k dielectrics in BEOL interconnects

    Science.gov (United States)

    Hong, Hyesook; Xing, Guoqiang; Mckerrow, Andrew; Kim, Tae S.; Smith, Patricia B.

    2002-07-01

    Printing small geometries using wavelength of 248 nm on low- k materials is not a plug-in photolithography process from one technology to other technology node. In this paper, a method of film characterization of low-k dielectric materials will be discussed. For a characterization of chemical vapor deposited low-k dielectric materials, a positive tone deep UV (DUV) chemically amplified photoresist (CAR) was used as a poisoning gauge. In early development state of low-k dielectrics and copper dual damascene interconnects in back-end-of-line processes, unstable patterning behaviors were observed in spite of using an organic bottom antireflective coating layers on low-k substrates. The initial work was focused on finding the source of lot-to-lot critical dimension (CD) variations and understanding what causes this problem as well. Study indicated a strong correlation that photo CD depended on time interval between photolithography process and previous process step. Significant photo CD shift was introduced by short cycle time from thin film deposition to photolithography process and post via etch clean process to trench photolithography process. To minimize photo CD variations, the process optimizations were necessary in low- k dielectric film deposition, rework, via etch process, and post via etch clean process. As parallel efforts to improve lot-to-lot CD control, various photoresist system, different ambient annealing conditions, various surface organic and inorganic capping techniques were tested. In this experiments, time interval between processes was tightly controlled and maximized the worst case of scenario. Fresh and aged low-k dielectric films were analyzed using time-of- flight secondary ion mass spectrometry and x-ray photoelectron spectroscopy techniques. This work suggested that N2 containing in the film or introducing N2 into low-k dielectric film caused lot-ot-lot photo CD variations.

  7. Ion Imaging Studies of CH_2I_2 Photodissociation at 248 NM

    Science.gov (United States)

    Lehman, Julia H.; Li, Hongwei; Lester, Marsha I.

    2013-06-01

    CH_2I_2 plays an important role in atmospheric chemistry as a significant natural source of organohalide compounds. The photodissociation dynamics of CH_2I_2 in the ultraviolet range of 277-305 nm via the two lowest B_1 excited states has been well studied using one-color velocity map ion imaging (VMI) and photofragment translational spectroscopy. In this two-color experimental study, CH_2I_2 is photodissociated by 248 nm via the B_2 or A_1 excited states to give rise to CH_2I and I (^2P_3_/_2) or I^* (^2P_1_/_2). The iodine atoms are then state selectively ionized using a (2+1) resonance-enhanced multiphoton ionization process near 310 nm and detected by VMI. Preliminary results show about 85% of the available energy is being funneled into the internal energy of the CH_2I fragment, consistent with prior infrared emission results of Baughcum and Leone. The anisotropy parameter derived from the image indicates this is a fast dissociation process and reflects the character of the electronic transition. The internal energy distribution of the CH_2I fragment is of particular interest because of its subsequent reaction with O_2 in a near thermo-neutral reaction to produce the smallest Criegee intermediate, CH_2OO. We anticipate that the internal energy contained in CH_2I will likely be carried into CH_2OO. S. L. Baughcum and S. R. Leone, J. Chem. Phys. 72, 6531 (1980).

  8. ATel 7470: Optical identification of the X-ray burster EXO 1745-248 in Terzan 5

    Science.gov (United States)

    Ferraro, F. R.; Pallanca, C.; Lanzoni, B.; Cadelano, M.; Massari, D.; Dalessandro, E.; Mucciarelli, A.

    2015-05-01

    We report on the identification of the optical counterpart to the neutron star transient EXO 1745-248 in the stellar system Terzan 5. The identification has been performed by exploiting a set of HST ACS/WFC images acquired in Director Discretionary Time on 2015 April 20 (MJD 57133), approximately 1 month after the Swift/BAT detection of an X-ray outburst from this source (Altamirano et al. ...

  9. Formation of copper tin sulfide films by pulsed laser deposition at 248 and 355 nm

    DEFF Research Database (Denmark)

    Ettlinger, Rebecca Bolt; Crovetto, Andrea; Canulescu, Stela;

    2016-01-01

    The influence of the laser wavelength on the deposition of copper tin sulfide (CTS) and SnS-rich CTS with a 248-nm KrF excimer laser (pulse length τ = 20 ns) and a 355-nm frequency-tripled Nd:YAG laser (τ = 6 ns) was investigated. A comparative study of the two UV wavelengths shows that the CTS...

  10. Hysteresis in the spectral states of the neutron star low-mass X-ray binary EXO 1745-248

    CERN Document Server

    Mukherjee, Arunava

    2011-01-01

    We study the low-frequency timing properties and the spectral state evolution of the transient neutron star low-mass X-ray binary EXO 1745-248 using the entire Rossi X-ray Timing Explorer Proportional Counter Array data. We tentatively conclude that EXO 1745-248 is an atoll source, and report the discovery of a ~ 0.45 Hz low-frequency quasi-periodic oscillation and ~ 10 Hz peaked noises. If it is an atoll, this source is unusual because (1) instead of a `C'-like curve, it traced a clear overall clockwise hysteresis curve in each of the colour-colour diagram and the hardness-intensity diagram; and (2) the source took at least 2.5 months to trace the softer banana state, as opposed to a few hours to a day, which is typical for an atoll source. The shape of the hysteresis track was intermediate between the characteristic `q'-like curves of several black hole systems and `C'-like curves of atolls, implying that EXO 1745-248 is an important source for the unification of the black hole and neutron star accretion pr...

  11. X-RAY EMISSION FROM STELLAR JETS BY COLLISION AGAINST HIGH-DENSITY MOLECULAR CLOUDS: AN APPLICATION TO HH 248

    Energy Technology Data Exchange (ETDEWEB)

    López-Santiago, J.; Ustamujic, S.; Castro, A. I. Gómez de [S. D. Astronomía y Geodesia, Facultad de Ciencias Matemáticas, Universidad Complutense de Madrid, E-28040 Madrid (Spain); Bonito, R.; Orlando, S. [Dipartimento di Fisica e Chimica, Università di Palermo, Piazza del Parlamento 1, I-90134 Palermo (Italy); Orellana, M. [Sede Andina de la Universidad Nacional de Río Negro (Argentina); Miceli, M. [INAF-Osservatorio Astronomico di Palermo, Piazza del Parlamento 1, I-90134 Palermo (Italy); Albacete-Colombo, J. F. [Sede Atlántica de la Universidad Nacional de Río Negro, Don Bosco y Leloir s/n, 8500 Viedma RN (Argentina); Castro, E. de [Dpto. de Astrofísica y CC. de la Atmósfera, Facultad de Física, Universidad Complutense de Madrid, E-28040 Madrid (Spain)

    2015-06-10

    We investigate the plausibility of detecting X-ray emission from a stellar jet that impacts a dense molecular cloud, a scenario that may be typical for classical T Tauri stars with jets in dense star-forming complexes. We first model the impact of a jet against a dense cloud using two-dimensional axisymmetric hydrodynamic simulations, exploring different configurations of the ambient environment. Then, we compare our results with XMM-Newton observations of the Herbig–Haro object HH 248, where extended X-ray emission aligned with the optical knots is detected at the edge of the nearby IC 434 cloud. Our simulations show that a jet can produce plasma with temperatures up to 10{sup 7} K, consistent with production of X-ray emission, after impacting a dense cloud. We find that jets denser than the ambient medium but less dense than the cloud produce detectable X-ray emission only at impact with the cloud. From an exploration of the model parameter space, we constrain the physical conditions (jet density and velocity and cloud density) that reproduce the intrinsic luminosity and emission measure of the X-ray source possibly associated with HH 248 well. Thus, we suggest that the extended X-ray source close to HH 248 corresponds to a jet impacting a dense cloud.

  12. Site-specific branching ratios for H-atom production from primary haloalkanes photolyzed at 193, 222, and 248 nm

    Science.gov (United States)

    Brum, Jeffrey L.; Deshmukh, Subhash; Wang, Zhongrui; Koplitz, Brent

    1993-01-01

    Selectively deuterated compounds are used to investigate the ``site-specific'' nature of H-atom production resulting from the photolysis of primary haloalkanes. The molecules investigated are 1-iodopropane, 1-bromopropane, iodoethane, bromoethane, and chloroethane, with photolysis being initiated at 193, 222, and 248 nm. Hydrogen and deuterium isotopes are systematically used to label chemically distinct carbon atoms within a given molecule. H- and D-atom Doppler profiles are generated via two-photon (121.6+364.7 nm) ionization resonant with Lyman-α, and the relative H/D ratios are used to quantify the probability for hydrogen production from each carbon site. In general, photolysis of an intermediate, presumably the alkyl radical, is implicated as being a key step in the overall process. When using 248 nm radiation, the photolysis process is dominated by C-H (or C-D) bond cleavage at the β carbon position regardless of the system investigated. In contrast, results using 193 nm excitation display no obvious preference for bond cleavage at a particular carbon site, again regardless of the system. The data produced by 222 nm photolysis show a qualitative tendency for C-H (or C-D) bond cleavage at the β carbon, but the quantitative results are not as self-consistent as either the 248 nm or the 193 nm data. Also, the results of ab initio calculations on the ground and excited states of the ethyl radical are used to help interpret the observed site specificity.

  13. Design of a homogeneous subcritical nuclear reactor based on thorium with a source of californium 252; Diseno de un reactor nuclear subcritico homogeneo a base de Torio con una fuente de Californio 252

    Energy Technology Data Exchange (ETDEWEB)

    Delgado H, C. E.; Vega C, H. R. [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Cipres No. 10, Fracc. La Penuela, 98068 Zacatecas, Zac. (Mexico); Sajo B, L., E-mail: ce_delgado89@hotmail.com [Universidad Simon Bolivar, Laboratorio de Fisica Nuclear, Apdo. 89000, 1080A Caracas (Venezuela, Bolivarian Republic of)

    2015-10-15

    Full text: One of the energy alternatives to fossil fuels which do not produce greenhouse gases is the nuclear energy. One of the drawbacks of this alternative is the generation of radioactive wastes of long half-life and its relation to the generation of nuclear materials to produce weapons of mass destruction. An option to these drawbacks of nuclear energy is to use Thorium as part of the nuclear fuel which it becomes in U{sup 233} when capturing neutrons, that is a fissile material. In this paper Monte Carlo methods were used to design a homogeneous subcritical reactor based on thorium. As neutron reflector graphite was used. The reactor core is homogeneous and is formed of 70% light water as moderator, 12% of enriched uranium UO{sub 2}(NO{sub 3}){sub 4} and 18% of thorium Th(NO{sub 3}){sub 4} as fuel. To start the nuclear fission chain reaction an isotopic source of californium 252 was used with an intensity of 4.6 x 10{sup 7} s{sup -1}. In the design the value of the effective multiplication factor, whose value turned out k{sub eff} <1 was calculated. Also, the neutron spectra at different distances from the source and the total fluence were calculated, as well as the values of the ambient dose equivalent in the periphery of the reactor. (Author)

  14. Manganese determination om minerals by activation analysis, using the californium-252 as a neutron source; Determinacao de manganes em minerios, por analise por ativacao, usando californio-252 como fonte de neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Cardoso, Antonio

    1976-07-01

    Neutron Activation Analysis, using a Californium-252 neutron source, has been applied for the determination of manganese in ores such as pyrolusite, rodonite (manganese silicate)' and blending used in dry-batteries The favorable nuclear properties of manganese, such as high thermal neutron cross-section for the reaction {sup 55}Mn (n.gamma){sup 56} Mn, high concentration of manganese in the matrix and short half - life of {sup 56}Mn, are an ideal combination for non-destructive analysis of manganese in ores. Samples and standards of manganese dioxide were irradiated for about 20 minutes, followed by a 4 to 15 minutes decay and counted in a single channel pulse-height discrimination using a NaI(Tl) scintillation detector. Counting time was equal to 10 minutes. The interference of nuclear reactions {sup 56}Fe(n,p){sup 56}Mn and {sup 59} Co (n, {alpha}){sup 56} were studied, as well as problems in connection with neutron shadowing during irradiation, gamma-rays attenuation during counting and influence of granulometry of samples. One sample,was also analysed by wet-chemical method (sodium bismuthate) in order to compare results. As a whole, i t was shown that the analytical method of neutron activation for manganese in ores and blending, is a method simple, rapid and with good precision and accuracy. (author)

  15. Acetone photolysis at 248 nm revisited: pressure dependence of the CO and CO2 quantum yields.

    Science.gov (United States)

    Somnitz, H; Ufer, T; Zellner, R

    2009-10-14

    Pressure dependent CO and CO2 quantum yields in the laser pulse photolysis of acetone at 248 nm and T = 298 K have been measured directly using quantitative infrared diode laser absorption. The experiments cover the pressure range from 50 to 900 mbar. It is found that the quantum yields show a significant dependence on total pressure, with Phi(CO) decreasing from around 0.5 at 20 mbar to approximately 0.3 at 900 mbar. The corresponding CO2 yields as observed when O2 exists in the reaction mixture, exhibit exactly the opposite behaviour. For the sum of both a value of 1.05(-0.05)(+0.02) independent of pressure is obtained, showing that the sum of (Phi(CO) + Phi(CO2)) is a measure for the primary quantum yield in the photolysis of acetone. In addition, CO quantum yields and corresponding pressure dependences were measured in experiments using different bath gases including He, Ar, Kr, SF6, and O2 as third body colliders. The theoretical framework in which we discuss these data is based on our previous findings that the pressure dependence of the CO yield is a consequence of a stepwise fragmentation mechanism during which acetone decomposes initially into methyl and a vibrationally 'hot' acetyl radical, with the latter being able to decompose promptly into methyl plus CO. The pressure dependence of the CO yield then originates from the second step and is modelled quantitatively via statistical dynamical calculations using a combination of RRKM theory with a time-dependent master equation (ME) approach. From a comparison of experiment with theory the amount of excess energy in the vibrationally hot acetyl radicals (E* approximately 65 kJ mol(-1)) as well as the characteristic collision parameters for interaction of acetyl with the different bath gases were derived. Values of 90, 280, 310, 545, 550 and 1800 cm(-1) for the average energy transferred per downward collision for the bath gases He, Ar, Kr, O2, N2, and SF6, respectively, are obtained. The calculations also

  16. A Compact Group of Galaxies at z = 2.48 Hosting an AGN-driven Outflow

    Science.gov (United States)

    Shih, Hsin-Yi; Stockton, Alan

    2015-12-01

    We present observations of a remarkable compact group of galaxies at z = 2.48. Four galaxies, all within 40 kpc of each other, surround a powerful high-redshift radio source. This group comprises two compact red passive galaxies and a pair of merging galaxies. One of the red galaxies, with an apparent stellar mass of 3.6 × 1011M⊙ and an effective radius of 470 pc, is one of the most extreme examples of a massive quiescent compact galaxy found so far. One of the pair of merging galaxies hosts the active galactic nucleus (AGN) producing the large powerful radio structure. The merger is massive and enriched, consistent with the mass-metallicity relation expected at this redshift. Close to the merging nuclei, the emission lines exhibit broad and asymmetric profiles that suggest outflows powered either by a very young expanding radio jet or by AGN radiation. At ≳50 kpc from the system, we found a fainter extended-emission region that may be a part of a radio-jet-driven outflow. Some of the data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. The work is also based, in part, on data collected at the Subaru Telescope, which is operated by the National Astronomical Observatory of Japan, and on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência, Tecnologia e Inovação (Brazil), and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina).

  17. Clinicopathologic study of 248 patients with FSGS%成人特发性局灶节段性肾小、球硬化病248例临床病理分析

    Institute of Scientific and Technical Information of China (English)

    郝翠兰; 王伟铭; 张惠新; 盛征; 俞建民; 陈楠

    2001-01-01

    目的重新评价肾活检标本中特发性局灶节段性肾小球硬化病(FSGS)的发生率、主要临床及病理特点。方法收集1994年7月~2000年7月间248例特发性FSGS的患者,观察肾组织的光镜、荧光及电镜的特点。根据肾小球病变将特发性FSGS分为3种亚型。结果248例成人特发性局灶节段性肾小球硬化占同期肾活检的12.4%,占成年人原发性肾小球疾病的19.0%,以18~30岁为发病高峰年龄(约占44.4%)。临床表现为不同程度的蛋白尿,以肾病综合征为表现者143例(占57.7%)。FSGS的3种病理亚型中,经典型FSGS仍占绝大多数(91.5%),尖端型为4.4%,塌陷型为4.1%。肾活检时,约l/3以上为肾功能不全(约占35.1%),13例尿毒症中76.996病理亚型为塌陷型。结论局灶节段性肾小球硬化病约占原发性肾小球病1/5,FSGS患者肾活检时,除表现为蛋白尿、肾病综合征外,肾功能不全也较常见。塌陷型FSGS常表现为进行性的不可逆的肾功能衰竭,其预后差。%Objective To analyze the incidence, clinical presentations and pathological changes of patients withprimary focal segmental glomerulosclerosis (FSGS). Methods 248 patients with biopsy proven primary FSGS wereenrolled. They were hospitalized during the period of 1994~ 2000. All tissues were evaluated by LM, IF and EM.They were divided into three subgroups based on glomerular changes. Results The incidence of adult primary FSGSwas 12.4% in all the biopsied patients in our hospital. About 19.0% of primary glomerular nephritis were FSGS, inwhich about 44.4 % of patients aged 18-30. The patients presented with nephrotic syndrome (143/248) or varying degrees of proteinuria (105/248). More than 1/3 of patients had renal failure, 14.9 % (13/248) patients had uremia. Among the subgroups of pathologic changes, 91.5% of patients had classical FSGS, 4.4% glomerular tip lesion and 4.1% collapsing glomerulo

  18. Replantation of severed limbs(fingers) at high altitude district:a clinical analysis of 248 cases%高原断肢(指)再植248例临床分析

    Institute of Scientific and Technical Information of China (English)

    韩国栋

    2001-01-01

    Objective To study the influence of coldness and hypoxia on thesevered limbs (fingers).Methods Retrospective analysis was done for 248 cases of severed limbs(fingers) at high altitude district in Qinghai province. The replantation sequence followed as normal procedure. But the number of arteries and veins anastomosed should be as many as possible. Sufficient blood volume and oxygen should be maintained with room temperature over 25 ℃.Results Overal viability rate was 90.8 % in 248 cases. 23 cases resulted in failure due to ischemic time over 10 hours.Conclusions Coldness at high altitude district provided tolerated ischemic warm time for detached limbs(fingers). People at high altitude district living in long - term hypoxia environment may increase adhensiveness of red blood cell and platelet, resulting in thrombosis after vessel anastomosis.%目的分析高寒、缺氧对断肢(指)再植的影响。方法对在青海省高原环境条件下行断肢(指)再植的248例病史作回顾性分析。再植顺序按断肢(指)再植常规,但应尽可能多地吻合动脉和静脉。在术中、术后保持一定的血容量、充足的氧气,室温需维持在25℃以上。结果248例的总成活率达90.8%。失败23例,大都为再植时限在10h以上者。结论高原地区的寒冷给离断肢(指)体提供了很好的冷藏条件,有利于提高成活率;高原地区人群的长期缺氧可增加血小板、红血球的粘附性,容易导致吻合后血管的血栓形成。

  19. Quantum yields for OH production from 193 and 248 nm photolysis of HNO3 and H2O2

    Science.gov (United States)

    Schiffman, A.; Nelson, D. D., Jr.; Nesbitt, D. J.

    1993-05-01

    Flash kinetic spectroscopy in a flow tube is used to measure at room temperature the absolute yields for OH production from 193 and 248 nm photolysis of HNO3 and H2O2. The OH radicals are produced by excimer laser photolysis and probed via direct absorption of high resolution tunable IR laser light. The results indicate quantum yields for both precursors at both wavelengths which are less than the maximum possible values of 1 for H2O2. The present measurements are discussed in light of contrasting results suggested from other work.

  20. Influence of nuclear dissipation on fission dynamics of the excited nucleus $^{248}$Cf within a stochastic approach

    Indian Academy of Sciences (India)

    ESLAMIZADEH HADI

    2016-07-01

    A stochastic approach to fission dynamics based on two-dimensional Langevin equations was applied to calculate the anisotropy of the fission fragments angular distribution and average pre-scission neutron multiplicities for the compound nucleus 248Cf formed in the $${16}$O+$^{232}$Th reactions. Postsaddle nuclear dissipation strength of $(12–14) \\times 10^{21} s^{−1}$ was extracted for Cf nucleus by fitting the results of calculations with the experimentaldata. Furthermore, it was found that the results of calculations for the anisotropy of the fission fragments angular distribution and pre-scission neutron multiplicities are very sensitive to the magnitude of post-saddle nucleardissipation.

  1. Photodissociation dynamics of the methyl perthiyl radical at 248 and 193 nm using fast-beam photofragment translational spectroscopy

    Science.gov (United States)

    Harrison, Aaron W.; Ryazanov, Mikhail; Sullivan, Erin N.; Neumark, Daniel M.

    2016-07-01

    The photodissociation dynamics of the methyl perthiyl radical (CH3SS) have been investigated using fast-beam coincidence translational spectroscopy. Methyl perthiyl radicals were produced by photodetachment of the CH3SS- anion followed by photodissociation at 248 nm (5.0 eV) and 193 nm (6.4 eV). Photofragment mass distributions and translational energy distributions were measured at each dissociation wavelength. Experimental results show S atom loss as the dominant (96%) dissociation channel at 248 nm with a near parallel, anisotropic angular distribution and translational energy peaking near the maximal energy available to ground state CH3S and S fragments, indicating that the dissociation occurs along a repulsive excited state. At 193 nm, S atom loss remains the major fragmentation channel, although S2 loss becomes more competitive and constitutes 32% of the fragmentation. The translational energy distributions for both channels are very broad at this wavelength, suggesting the formation of the S2 and S atom products in several excited electronic states.

  2. Disc-Jet Coupling in the Terzan 5 Neutron Star X-ray Binary EXO 1745$-$248

    CERN Document Server

    Tetarenko, A J; Sivakoff, G R; Tremou, E; Linares, M; Tudor, V; Miller-Jones, J C A; Heinke, C O; Chomiuk, L; Strader, J; Altamirano, D; Degenaar, N; Maccarone, T; Patruno, A; Sanna, A; Wijnands, R

    2016-01-01

    We present the results of VLA, ATCA, and Swift XRT observations of the 2015 outburst of the transient neutron star X-ray binary (NSXB), EXO 1745$-$248, located in the globular cluster Terzan 5. Combining (near-) simultaneous radio and X-ray measurements we measure a correlation between the radio and X-ray luminosities of $L_R\\propto L_X^\\beta$ with $\\beta=1.68^{+0.10}_{-0.09}$, linking the accretion flow (probed by X-ray luminosity) and the compact jet (probed by radio luminosity). While such a relationship has been studied in multiple black hole X-ray binaries (BHXBs), this work marks only the third NSXB with such a measurement. Constraints on this relationship in NSXBs are strongly needed, as comparing this correlation between different classes of XB systems is key in understanding the properties that affect the jet production process in accreting objects. Our best fit disc-jet coupling index for EXO 1745$-$248 is consistent with the measured correlation in NSXB 4U 1728$-$34 ($\\beta=1.5\\pm 0.2$) but inconsi...

  3. Study on application of designing CAN bus using PIC18F248 chip%PIC18F248芯片在CAN总线设计中的应用

    Institute of Scientific and Technical Information of China (English)

    孙双花; 曲兴华; 杨学友; 叶声华

    2004-01-01

    CAN总线因为其突出的可靠性、实时性和灵活性等特点被广泛应用于分布式网络系统中.在基于CAN总线的分布式分层网络控制系统中,利用带有CAN接口的高性能的PIC18F248单片机设计了CAN总线接口,给出了CAN接口的硬件电路及软件流程.该电路具有硬件设计简单、可靠性高、实时性强等特点.

  4. 基于PIC18F248的SPWM波生成的一种方法%A Method of Producing SPWM Waveform Based on PIC18F248

    Institute of Scientific and Technical Information of China (English)

    代玉伟; 李敬东; 唐跃进; 石晶

    2007-01-01

    随着超导技术和电力电子技术的发展,三相电流源型变流器(CSC)在超导储能领域依然占有主导地位.文中详细地介绍了电流型变流器(CSC)的正弦脉宽调制方法.该方法利用MCU PIC18F248产生SPWM波,采用查表和在线计算相结合,既能满足一定控制精度,又能满足实时控制要求,同时给出了整个程序流程图.实验结果验证了该方法的正确性和可行性.

  5. Operational tests of the BNL 24.8 kW, 3.8 K helium refrigerator

    Science.gov (United States)

    Brown, D. P.; Farah, Y.; Gibbs, R. J.; Schlafke, A. P.; Sondericker, J. H.; Wu, K. C.; Freeman, M.; Ganni, V.; Kowalski, R.; McWilliams, R.

    1985-06-01

    The BNL 24.8 kW refrigeration system is completely installed and major portions of the acceptance tests have been completed. So far, the equipment tested has performed at or above design levels. The room temperature helium compressor station has been completely tested and accepted. The two-stage oil injected screw compressor system exhibited an isothermal efficiency of 57% while delivering a helium flow in excess of 4400 g/s. Data on the performance of the make-up gas cryogenic purifier is given. The refrigerator turbomachinery, 13 expanders and three cold compressors, has been tested at room temperature for mechanical integrity and control stability. The first cooldown to operating temperature will be attempted in late August, 1985.

  6. Analysis of polymorphisms in codons 11, 72 and 248 of TP53 in Brazilian women with breast cancer.

    Science.gov (United States)

    Almeida, B C; Kleine, J P F O; Camargo-Kosugi, C M; Lisboa, M R; França, C N; França, J P; Silva, I D C G

    2016-02-22

    The association between TP53 gene polymorphisms and breast cancer (BC) in Brazilian women is a controversial topic. In this cross-sectional study, we evaluated the association between clinical pathological variables and three polymorphisms (TP53*11, TP53*72, and TP53*248) in BC patients and controls. Genomic DNA was extracted from the blood cells of 393 participants; the cancer-free control subjects were 26-72 years old (41 ± 11.03) and the BC patients were 28-80 years old (51 ± 10.70). We used standard polymerase chain reaction-restriction fragment length polymorphism and confirmed the results by genetic sequencing. In TP53*11, there was 100% homozygous Glu distribution in both groups. TP53*72 showed genotypic distribution: in the control group, there was 16.10% homozygous Pro, and 42.44% heterozygous and 41.46% homozygous Arg; in the BC group, there was 15.43% homozygous Pro, and 42.55% heterozygous and 42.02% homozygous Arg. The relative frequency of each allele was 0.37% for Pro and 0.63% for Arg in the control group, and 0.37% for Pro and 0.63% for Arg in the BC group. The nuclear grade (P = 0.0084) and adapted histological grade (P = 0.0265) were associated with TP53*72. The distribution of the codon 72 genotypes did not deviate from Hardy-Weinberg equilibrium in either group. In TP53*248, there was 100% homozygous Arg distribution in both groups. In codon 72, the Arg allele is the most prevalent in Brazilian women. TP53*72 may be associated with susceptibility to BC, although more studies are required to evaluate the profile of Brazilian women with BC.

  7. Dental implant restoration in 248 patients with periodontal disease and type 2 diabetes%牙周病伴2型糖尿病248例种植义齿治疗总结

    Institute of Scientific and Technical Information of China (English)

    吴大怡; 李刚; 张青; 滕立钊; 卢焕友

    2011-01-01

    Objective To discuss the risk and strategy of dental implantation in patients with periodontal disease and type 2 diabetes.Methods Retrospective analysis was performed of dental implantation results in 248 patients with periodontal disease and type 2 diabetes from 2000 to 2008.The survival rate was evaluated and the data statistically analyzed.Results The Nobel implant system and CDIC implant system were used.The operation applied flapless and bone expanding techniques.A total of 1190 implants were inserted (333 Nobel Replace implants and 857 CDIC implants).0.5% (6 implants) lost during the first 6 months healing stage.The l-year,5-year and 8-year survival rate were 98.4% (1165/1184),95.3%(487/511)and 89.2%(91/102) respectively.Conclusions The patients with periodontal disease and type 2 diabetes are suitable for implant treatment with satisfactory results under the conditions that the indication and risk factors are evaluated and controlled strictly.%目的 探讨牙周病伴2型糖尿病患者实施种植义齿治疗的风险和处理对策.方法 回顾分析2000至2008年在成都华西牙种植医院、华西口腔深圳门诊部、华西口腔重庆门诊部接受种植义齿治疗的248例牙周病伴2型糖尿病患者,以种植体存留率为评价指标,对数据进行统计分析.结果 248例患者选用Nobel Replace和CDIC两个种植系统,采用不翻瓣和骨膨胀的微创植入术,共植入牙种植体1190枚(Nobel Replace 333枚、CDIC 857枚).6枚(0.5%)种植体在术后6个月愈合期内脱落,术后1年种植体存留率为98.4% (1165/1184)、5年存留率为95.3% (487/511)、8年存留率为89.2% (91/102).结论 严格掌握适应证和控制风险的情况下,牙周病伴2型糖尿病患者种植修复可获得较高的满意度.

  8. Probing the MSP Prenatal Stage: The Optical Identification of the X-Ray Burster EXO 1745-248 in Terzan 5

    NARCIS (Netherlands)

    Ferraro, F. R.; Pallanca, C.; Lanzoni, B.; Cadelano, M.; Massari, D.; Dalessandro, E.; Mucciarelli, A.

    2015-01-01

    We report on the optical identification of the neutron star burster EXO 1745-248 in Terzan 5. The identification was performed by exploiting Hubble Space Telescope/Advanced Camera for Surveys images acquired in Director's Discretionary Time shortly after (approximately one month) the Swift detection

  9. High throughput virtual screening and in silico ADMET analysis for rapid and efficient identification of potential PAP248-286 aggregation inhibitors as anti-HIV agents

    Science.gov (United States)

    Malik, Ruchi; Bunkar, Devendra; Choudhary, Bhanwar Singh; Srivastava, Shubham; Mehta, Pakhuri; Sharma, Manish

    2016-10-01

    Human semen is principal vehicle for transmission of HIV-1 and other enveloped viruses. Several endogenous peptides present in semen, including a 39-amino acid fragments of prostatic acid phosphatase (PAP248-286) assemble into amyloid fibrils named as semen-derived enhancer of viral infection (SEVI) that promote virion attachment to target cells which dramatically enhance HIV virus infection by up to 105-fold. Epigallocatechin-3-gallate (EGCG), a polyphenolic compound, is the major catechin found in green tea which disaggregates existing SEVI fibers, and inhibits the formation of SEVI fibers. The aim of this study was to screen a number of relevant polyphenols to develop a rational approach for designing PAP248-286 aggregation inhibitors as potential anti-HIV agents. The molecular docking based virtual screening results showed that polyphenolic compounds 2-6 possessed good docking score and interacted well with the active site residues of PAP248-286. Amino acid residues of binding site namely; Lys255, Ser256, Leu258 and Asn265 are involved in binding of these compounds. In silico ADMET prediction studies on these hits were also found to be promising. Polyphenolic compounds 2-6 identified as hits may act as novel leads for inhibiting aggregation of PAP248-286 into SEVI.

  10. The hard quiescent spectrum of the neutron-star X-ray transient EXO 1745-248 in the globular cluster Terzan 5

    CERN Document Server

    Wijnands, R; Pooley, D; Edmonds, P D; Lewin, W H G; Grindlay, J E; Jonker, P G; Miller, J M; Wijnands, Rudy; Heinke, Craig O.; Pooley, David; Edmonds, Peter D.; Lewin, Walter H. G.; Grindlay, Jonathan E.; Jonker, Peter G.; Miller, Jon M.

    2003-01-01

    We present a Chandra observation of the globular cluster Terzan 5 during times when the neutron-star X-ray transient EXO 1745-248 located in this cluster was in its quiescent state. We detected the quiescent system with a (0.5-10 keV) luminosity of ~2 x 10^{33} ergs/s. This is similar to several other neutron-star transients observed in their quiescent states. However, the quiescent X-ray spectrum of EXO 1745--48 was dominated by a hard power-law component instead of the soft component that usually dominates the quiescent emission of other neutron-star X-ray transients. This soft component could not conclusively be detected in EXO 1745-248 and we conclude that it contributed at most 10% of the quiescent flux in the energy range 0.5-10 keV. EXO 1745-248 is only the second neutron-star transient whose quiescent spectrum is dominated by the hard component (SAX J1808.4-3658 is the other one). We discuss possible explanations for this unusual behavior of EXO 1745-248, its relationship to other quiescent neutron-st...

  11. Analysis Of Nevus of Ota Treated By Q-switched Nd:YAG Laser(Reported of 248 Cases)%调Q开关Nd:YAG激光治疗太田痣疗效分析(附248报告)

    Institute of Scientific and Technical Information of China (English)

    钟贵玲; 黄敏; 吴少珠; 胡瑛; 李素霞; 颜玲

    2008-01-01

    目的 探讨调Q开关Nd:YAG激光治疗太田痣的临床疗效.方法 采用广州激光技术应用研究所生产的调Q开关Nd:YAG激光美容机,波长1064 nm,单脉冲能量:50~800mJ可调;波长532nm,单脉冲能量:20~400mJ可调;脉冲频率:1次/秒、2次/秒、5次/秒、10次/秒.脉宽:8~10 ns,光斑直径:1~6 mm可调.248例太田痣病人分A、B、C三组进行治疗.每3个月治疗一次.结果 A组82例太田痣病人治愈27例,治愈率33%.B组84例太田痣病人治愈35例,治愈率41.6%.C组82例太田痣病人治愈48例,治愈率58.5%.结论 用调Q开关Nd:YAG激光治疗太田痣,有效、安全.

  12. Cervical foraminal steroid injections under CT guidance: retrospective study of in situ contrast aspects in a serial of 248 cases

    Energy Technology Data Exchange (ETDEWEB)

    Pottecher, Pierre; Krause, Denis; Di Marco, Lucy; Loffroy, Romaric; Estivalet, Louis [CHU Dijon Bocage Central, Departement de Radiologie et Imagerie Diagnostique et Interventionnelle, Dijon (France); Duhal, Romain; Demondion, Xavier [CHRU de Lille, Service de Radiologie Musculosquelettique, CCIAL, Laboratoire d' Anatomie, Faculte de Medecine de Lille, Hopital Roger Salengro, Lille (France)

    2015-01-15

    To describe all the CT findings after in situ contrast injection just before steroid injection and to recognize the abnormal aspects associated with intravascular contamination. We retrospectively evaluated 248 cervical transforaminal steroid injections done at the university hospital in Dijon, France, in 2008-2012, to treat cervicobrachial neuralgia inadequately improved by optimal medical treatment for at least 3 weeks. Features describing the opacification patterns were recorded. Five main nonvascular opacification patterns were identified: clumps of contrast agent outside the foramen (16 %), a crab claw pattern surrounding the ganglion (13 %), a ''French'' circumflex accent pattern (15 %), reflux along the needle (7 %), and facet joint capsule opacification (22 %). Concerning the situations requiring a change in needle position, intravenous injection occurred in 26 % of the patients, with a crab claw pattern in half the cases and a clump pattern in half the cases. Intraarteriolar injection was noted in two patients. CT after in situ contrast injection ensures proper needle positioning outside the blood vessels before steroid injection. Penetration of the needle tip into a vein is very common, whereas arteriolar puncture is extremely rare. (orig.)

  13. Analysis of damage threshold of K9 glass irradiated by 248-nm KrF excimer laser

    Science.gov (United States)

    Wang, Xi; Shao, Jingzhen; Li, Hua; Nie, Jinsong; Fang, Xiaodong

    2016-02-01

    The theoretical model of K9 glass irradiated by a 248-nm KrF excimer laser was established, and a numerical simulation was performed to calculate temperature and thermal stress fields in the K9 glass sample using the finite element method. The laser-induced damage thresholds were defined and calculated, and the effect of repetition frequency and the number of pulses on the damage threshold were also studied. Furthermore, the experiment research was carried out to confirm the numerical simulation. The damage threshold and damage morphology were analyzed by means of a metallurgical microscope and scanning electron microscopy. The simulation and experimental results indicated that the damage mechanism of K9 glass irradiated by a KrF excimer laser was melting damage and stress damage, and the stress damage first appeared inside the K9 glass sample. The tensile stress damage threshold, the compressive stress damage threshold, and the melting damage threshold were 0.64, 0.76, and 1.05 J/cm2, respectively. The damage threshold decreased with increasing repetition frequency and number of laser pulses. The experimental results indicated that the damage threshold of K9 glass was 2.8 J/cm2.

  14. On the photochemistry of IONO2: absorption cross section (240-370 nm) and photolysis product yields at 248 nm.

    Science.gov (United States)

    Joseph, D M; Ashworth, S H; Plane, J M C

    2007-11-01

    The absolute absorption cross section of IONO(2) was measured by the pulsed photolysis at 193 nm of a NO(2)/CF(3)I mixture, followed by time-resolved Fourier transform spectroscopy in the near-UV. The resulting cross section at a temperature of 296 K over the wavelength range from 240 to 370 nm is given by log(10)(sigma(IONO(2))/cm(2) molecule(-1)) = 170.4 - 3.773 lambda + 2.965 x 10(-2)lambda(2)- 1.139 x 10(-4)lambda(3) + 2.144 x 10(-7)lambda(4)- 1.587 x 10(-10)lambda(5), where lambda is in nm; the cross section, with 2sigma uncertainty, ranges from (6.5 +/- 1.9) x 10(-18) cm(2) at 240 nm to (5 +/- 3) x 10(-19) cm(2) at 350 nm, and is significantly lower than a previous measurement [J. C. Mössinger, D. M. Rowley and R. A. Cox, Atmos. Chem. Phys., 2002, 2, 227]. The photolysis quantum yields for IO and NO(3) production at 248 nm were measured using laser induced fluorescence of IO at 445 nm, and cavity ring-down spectroscopy of NO(3) at 662 nm, yielding phi(IO) iodine oxides, but the formation and subsequent photolysis of IONO(2) is very inefficient as an ozone-depleting cycle.

  15. X-ray emission from stellar jets by collision against high-density molecular clouds: an application to HH 248

    CERN Document Server

    Lopez-Santiago, Javier; Orellana, Mariana; Miceli, Marco; Orlando, Salvatore; Ustamujic, Sabina; Albacete-Colombo, Juan Facundo; de Castro, Elisa; de Castro, Ana Ines Gomez

    2015-01-01

    We investigate the plausibility of detecting X-ray emission from a stellar jet that impacts against a dense molecular cloud. This scenario may be usual for classical T Tauri stars with jets in dense star-forming complexes. We first model the impact of a jet against a dense cloud by 2D axisymmetric hydrodynamic simulations, exploring different configurations of the ambient environment. Then, we compare our results with XMM-Newton observations of the Herbig-Haro object HH 248, where extended X-ray emission aligned with the optical knots is detected at the edge of the nearby IC 434 cloud. Our simulations show that a jet can produce plasma with temperatures up to 10 MK, consistent with production of X-ray emission, after impacting a dense cloud. We find that jets denser than the ambient medium but less dense than the cloud produce detectable X-ray emission only at the impact onto the cloud. From the exploration of the model parameter space, we constrain the physical conditions (jet density and velocity, cloud den...

  16. Effect of nitrogen supply and Azospirillum brasilense Sp-248 on the response of wheat to seawater irrigation.

    Science.gov (United States)

    Alamri, Saad A; Mostafa, Yasser S

    2009-10-01

    Response of wheat to Azospirillum brasilense Sp-248 inoculation with different N-fertilizer levels using seawater irrigation was investigated. All inoculated treatments increased plant height, shoot and root dry weight, and tiller number in compared with uninoculated treatments. Yield parameters measured were also increased due to the inoculation. In terms of the effect of saline irrigation, there were no significant differences in growth and yield parameters in plants treated with tap water and others irrigated with 8.0% seawater concentration. This would indicate a relatively high tolerance of A. brasilense to saline irrigation and its ability to reduce the deleterious effects of saline on growth by increasing the plant's adaptation. However, increasing the seawater concentration in the irrigation water to 16.0% significantly decreased all tested parameters. Inoculation treatments generally increased NPKCa contents and decreased sodium ratio of the grains in compared with the uninoculated treatments. Overall results clearly revealed that the Azospirillum inoculation saved about 20 units of N-fertilizer and that saving was made economically feasible by decreasing the chemical fertilizers needed, improving the nitrogen content and counteracting the effects of salinity.

  17. Photosensitivity of the Er/Yb-Codoped Schott IOG1 Phosphate Glass Using 248 nm, Femtosecond, and Picosecond Laser Radiation

    OpenAIRE

    Pissadakis, Stavros; Michelakaki, Irini

    2008-01-01

    The effect of 248 nm laser radiation, with pulse duration of 5 picoseconds, 500 femtoseconds, and 120 femtoseconds, on the optical properties and the Knoop hardness of a commercial Er/Yb-codoped phosphate glass is presented here. Refractive index changes of the order of few parts of 10-4 are correlated with optical absorption centers induced in the glass volume, using Kramers-Kroning relationship. Accordingly, substantially lower refractive index changes are measured in volume Bragg gratings ...

  18. Photolytic behaviour of methane @ lyman alpha and 248 nm : studies in the frame of a simulation program of Titan's atmosphere (S.E.T. U.P.)

    Science.gov (United States)

    Gazeau, M. C.; Romanzin, C.; Benilan, Y.; Jolly, A.

    An experimental simulation program called S E T U P Theoretical and Experimental Simulations Useful for Planetology is currently developped in our laboratory One of our aim is to investigate the mechanisms implied in the atmospheric chemistry of Titan in order to improve their description in theoretical models Experimental simulations are planned using a dedicated device The latter consists of a reactor where the initial gas mixture will be submitted for the first time to both major energy sources that are responsible for the chemical evolution of Titan s atmosphere electrons and photons Cold plasma and a UV irradiation will be used to dissociate N 2 and CH 4 respectively Time resolved analysis of the resulting gas sample will be done using spectroscopic methods In Titan s atmosphere photolysis of methane mainly involves Lyman- alpha photons 121 6 nm Such mechanism can not be easily reproduced in the laboratory for several reasons - difficulty to work in the VUV range traditional photochemical lamps unsuitable for high speed kinetic studies ldots Therefore in our simulation experiments a pulsed laser KrF excimer delivering photons at 248 nm is used to dissociate methane Indeed a two photons 248 nm process is energetically equivalent to the single photon 121 6 nm one Hovewer branching ratios for the CH 3 CH 2 and CH radicals production and consequently the following photochemistry could be different Thus as a first step of this photochemical experiment photolysis of methane at 121 6 and 248 nm

  19. GMRT and VLA Observations at 49 cm and 20 cm of the HII Region near = 24.8°, = 0.1°

    Indian Academy of Sciences (India)

    N. G. Kantharia; W. M. Goss; D. Anish Roshi; Niruj R. Mohan; Francois Viallefond

    2007-03-01

    We report multi-frequency radio continuum and hydrogen radio recombination line observations of HII regions near = 24.8°, = 0.1° using the Giant Metrewave Radio Telescope(GMRT) at 1.28 GHz ( = 172), 0.61 GHz ( = 220) and the Very Large Array (VLA) at 1.42 GHz ( = 166). The region consists of a large number of resolved HII regions and a few compact HII regions as seen in our continuum maps, many of which have associated infrared (IR) point sources. The largest HII region at = 24.8° and = 0.1° is a few arcmins in size and has a shell-type morphology. It is a massive HII region enclosing ∼ 550 M⊙ with a linear size of 7 pc and an rms electron density of ∼ 110 cm-3 at a kinematic distance of 6 kpc. The required ionization can be provided by a single star of spectral type O5.5. We also report detection of hydrogen recombination lines from the HII region at = 24.8° and = 0.1° at all observed frequencies near = 100 km s-1. We model the observed integrated line flux density as arising in the diffuse HII region and find that the best fitting model has an electron density comparable to that derived from the continuum.We also report detection of hydrogen recombination lines from two other HII regions in the field.

  20. Association of Polymorphism in MC1R Gene at Site 248 with Chestnut Coat Color in Three Chinese Horse Breeds%黑色素皮质激素受体1基因248位点多态性与中国马品种毛色的相关性分析

    Institute of Scientific and Technical Information of China (English)

    党珍; 王嘉福; 赵星艳; 黄勇; 田松军; 王荣明; 冉雪琴

    2012-01-01

    A single nucleotide polymorphism (SNP) at site 248 of melanocortin receptor 1 gene (MC1R) is known from European horse breeds, in which the homozygous genotype (ee) is related with the chestnut coat color of European horse individuals. To confirm the polymorphism of site 248 of MCliR gene in Chinese horse, three horse breeds of Guizhou pony, Southwest horse and I1ii horse were chosen as samples with coat color of three monochromatic (chestnut, black, bay) and three kinds of complex coat color. Two pairs specific primers were designed. Two fragments, 124 and 481 bp, were amplificated by allele-specific polymerase chain reaction (AS-PCR) method. The polymorphism of site 248 in MClR gene was further approved by cloning and sequencing of the DNA fragments. The results showed that genotypes of all samples with coat color of chestnut were heterozygous genotype (Ee). However, the genotypes of other samples were Ee either, in which the coat colors included bay, black, grey, spotted but not chestnut. It suggested that the SNP at site 248 of MC1R gene might be unrelated with the chestnut coat color in native Chinese horse breeds.%在欧洲马品种中,黑色素皮质激素受体1(melanocortin receptor1,MC1R)基因第248位碱基有C/T多态性,纯合的T248位点决定欧洲马的栗毛色.针对MC1R基因的248位点设计了2对特异性引物,采用等位基因特异性PCR技术,研究3个中国马品种MC1R基因型与栗色毛之间的关系.经扩增获得两种DNA片段,克隆测序后证明,扩增片段确为MC1R基因,两种DNA片段序列在基因的248位点的确星现C/T多态性,但检测126份贵州矮马、西南马和新疆伊犁马血液样本,全部为杂合基因型(Ee),其中包括栗毛、黑毛、骝毛3种单毛色及3种复毛色.这些研究结果提示,MC1R基因中248位点的多态性与国内3个马品种的栗色毛之间没有直接的相关性.

  1. Residues 248-252 and 300-304 of the cardiac Na+/Ca2+ exchanger are involved in its regulation by phospholemman.

    Science.gov (United States)

    Zhang, Xue-Qian; Wang, JuFang; Song, Jianliang; Ji, Angi M; Chan, Tung O; Cheung, Joseph Y

    2011-10-01

    Using split cardiac Na(+)/Ca(2+) exchangers (NCX1), we previously demonstrated that phospholemman (PLM) regulates NCX1 by interacting with the proximal linker domain (residues 218-358) of the intracellular loop of NCX1. With the use of overlapping loop deletion mutants, interaction sites are localized to two regions spanning residues 238-270 and residues 300-328 of NCX1. In this study, we used alanine (Ala) linker scanning to pinpoint the residues in the proximal linker domain involved in regulation of NCX1 by PLM. Transfection of human embryonic kidney (HEK)293 cells with wild-type (WT) NCX1 or its Ala mutants but not empty vector resulted in NCX1 current (I(NaCa)). Coexpression of PLM with WT NCX1 inhibited I(NaCa). Mutating residues 248-252 (PASKT) or 300-304 (QKHPD) in WT NCX1 to Ala resulted in loss of inhibition of I(NaCa) by PLM. By contrast, inhibition of I(NaCa) by PLM was preserved when residues 238-242, 243-247, 253-257, 258-262, 263-267, 305-309, 310-314, 315-319, 320-324, or 325-329 were mutated to Ala. While mutating residue 301 to alanine completely abolished PLM inhibition, mutation of any single residue 250-252, 300, or 302-304 resulted in partial reduction in inhibition. Mutating residues 248-252 to Ala resulted in significantly weaker association with PLM. The NCX1-G503P mutant that lacks Ca(2+)-dependent activation retained its sensitivity to PLM. We conclude that residues 248-252 and 300-304 in the proximal linker domain of NCX1 were involved in its inhibition by PLM.

  2. Lack of association between Bax promoter (-248G>A single nucleotide polymorphism and susceptibility towards cancer: evidence from a meta-analysis.

    Directory of Open Access Journals (Sweden)

    Sushil Kumar Sahu

    Full Text Available BACKGROUND: The Bcl-2-associated X protein (Bax is a proapoptotic member of the Bcl-2 family known to be activated and upregulated during apoptosis. Single nucleotide polymorphisms (SNPs in Bax promoter may participate in the process of carcinogenesis by altering its own expression and the cancer related genes. Bax-248G>A polymorphism has been implicated to alter the risk of cancer, but the listed results are inconsistent and inconclusive. In the present study, we performed a meta-analysis to systematically summarize the possible association of this polymorphism with the risk of cancer. METHODOLOGY: We conducted a search of case-control studies on the associations of Bax-248G>A polymorphism with susceptibility to cancer in Pub Med, Science Direct, Wiley Online Library and hand search. Data from all eligible studies based on some key search terms, inclusion and exclusion criteria were extracted for this meta-analysis. Hardy-Weinberg equilibrium (HWE in controls, power calculation, heterogeneity analysis, Begg's funnel plot, Egger's linear regression test, forest plot and sensitivity analysis were performed in the present study. RESULTS: Cancer risk associated with Bax-248G>A polymorphism was estimated by pooled odds ratios (ORs and 95% confidence intervals (95% CIs. The pooled ORs were calculated in allele contrast, homozygous comparison, heterozygous comparison, dominant and recessive model. Statistical significance was checked through Z and p-value in forest plot. A total of seven independent studies including 1772 cases and 1708 controls were included in our meta-analysis. Our results showed that neither allele frequency nor genotype distributions of this polymorphism were associated with risk for cancer in any of the genetic model. Furthermore, Egger's test did not show any substantial evidence of publication bias. CONCLUSIONS/SIGNIFICANCE: This meta-analysis suggests that the Bax-248G>A polymorphism is not an important cancer risk factor

  3. Insolation data manual: long-term monthly averages of solar radiation, temperature, degree-days and global anti K/sub T/ for 248 national weather service stations

    Energy Technology Data Exchange (ETDEWEB)

    Knapp, C L; Stoffel, T L; Whitaker, S D

    1980-10-01

    Monthly averaged data is presented which describes the availability of solar radiation at 248 National Weather Service stations. Monthly and annual average daily insolation and temperature values have been computed from a base of 24 to 25 years of data. Average daily maximum, minimum, and monthly temperatures are provided for most locations in both Celsius and Fahrenheit. Heating and cooling degree-days were computed relative to a base of 18.3/sup 0/C (65/sup 0/F). For each station, global anti K/sub T/ (cloudiness index) were calculated on a monthly and annual basis. (MHR)

  4. Dental implant therapy in 248 periodontal disease patients with type Ⅱ diabetes: an observation study%248例牙周病伴糖尿病患者的种植义齿治疗

    Institute of Scientific and Technical Information of China (English)

    吴大怡; 李刚; 张青; 滕立钊; 卢焕友

    2010-01-01

    目的:通过牙周病伴糖尿病失牙患者种植义齿修复综合治疗的长期观察,了解糖尿病患者接受种植治疗后可能产生的效果以及探讨实施种植义齿修复的风险和处理对策.材料和方法:本中心统计了2000至2008年问在所属医疗机构接受种植义齿治疗的1240例牙周病患者(平均每人缺牙超过3枚),其中确诊为Ⅱ型糖尿病的患者有248例,共植入牙种植体1190枚(CDIC 857枚,Replace 333枚),约占牙周病患者总数的20%;男性136例,女性112例;最低年龄28岁,最高年龄93岁,平均53岁.该类型患者种植治疗前的空腹血糖水平最高者为12.3mmol/L;最低为6.3mmol/L;平均水平8.3 mmol/L;种植术前控制血糖平均水平≤7.4 mmol/L.术前对患者局部骨量水平进行检测评估,全部病例符合牙种植手术最基本要求,酌情采用即刻种植和延期种植两种手术方式;选用CDIC和Replace两个牙种植体系统;种植术式基本采用不翻瓣和骨膨胀的微创植入术;义齿修复时间选择在术后6个月进行;种植术前和术后针对患者具体情况给予控制高血糖可能导致风险的相应对策和补充措施.结果:本次研究病例统计为1-8年的在院治疗病例,其中种植义齿修复前(术后6个月时间内)植体脱落数量有6枚(约5‰),术后1年存留率为98.4%、5年存留率为95.4%、8年存留率为89.4%,保存种植体及种植义齿使用最长时间>96月,最短时间1月.患者空腹血糖水平控制平稳,均无较大波动.患者对种植义齿修复的满意度较高.讨论:国内外学者的研究表明,糖尿病的高发病率是直接导致牙周病患者增加和失牙率升高的重要因素之一.在牙列缺损或缺失的患者中,同时伴有糖尿病的患者其缺牙情况较单纯因龋病或根尖周病而致的牙列缺损或缺失情况为多、牙槽骨吸收严重、余留天然牙条件较差、传统固定桥和活动义齿修复困难等特点.从牙

  5. A strong emission line near 24.8 angstrom in the X-ray binary system MAXI J0556--332: gravitational redshift or unusual donor?

    CERN Document Server

    Maitra, Dipankar; Raymond, John C; Reynolds, Mark T

    2011-01-01

    We report the discovery of a strong emission line near 24.8 angstrom (0.5 keV) in the newly discovered X-ray binary system MAXI J0556-332 with the reflection grating spectrometer onboard the XMM-Newton observatory. The X-ray light curve morphology during these observations is complex and shows occasional dipping behavior. Here we present time- and rate-selected spectra from the RGS and show that this strong emission line is unambiguously present in all the XMM observations. The measured line center is consistent with the Ly-alpha transition of N VII in the rest frame. While the spectra contain imprints of absorption lines and edges, there appear to be no other significantly prominent narrow line due to the source itself, thus making the identification of the 24.8 angstrom line uncertain. We discuss possible physical scenarios, including a gravitationally redshifted O VIII Ly-alpha line originating at the surface of a neutron star or an unusual donor with an extremely high N/O abundance (>57) relative to solar...

  6. Phosphorylation of Serine 248 of C/EBPa Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency

    DEFF Research Database (Denmark)

    Hasemann, Marie S; Schuster, Mikkel B; Frank, Anne-Katrine;

    2012-01-01

    Transcription factors play a key role in lineage commitment and differentiation of stem cells into distinct mature cells. In hematopoiesis, they regulate lineage-specific gene expression in a stage-specific manner through various physical and functional interactions with regulatory proteins......, alternative translation, protein interactions and posttranslational modifications, such as phosphorylation. In particular, the phosphorylation of serine 248 of the transactivation domain has been shown to be of crucial importance for granulocytic differentiation of 32Dcl3 cells in vitro....... that are simultanously recruited and activated to ensure timely gene expression. The transcription factor CCAAT/enhancer binding protein a (C/EBPa) is such a factor and is essential for the development of granulocytic/monocytic cells. The activity of C/EBPa is regulated on several levels including gene expression...

  7. Pulsed laser positive ion desorption from a model hydrated inorganic crystal (CaHPO 4·2H 2O) at 248 nm

    Science.gov (United States)

    Dawes, M. L.; Langford, S. C.; Dickinson, J. T.

    1998-05-01

    We examine the laser-induced positive ion emission of a typical, wide band gap, hydrated inorganic single crystal, CaHPO 4·2H 2O (brushite), at 248 nm (KrF excimer) in vacuum. As-grown brushite is quite resistant to laser damage and yields little ion emission at fluences below 1 J/cm 2. In the presence of surface damage by abrasion or heating-induced transformations, intense laser-induced ion emission appears at lower fluences. The ion energy and fluence dependence are consistent with a defect mediated, multiple photon emission mechanism. In particular, the transport of hydrated Ca + to the surface, followed by adsorption at anion defects (and removal of water by evaporation), can provide an ideal environment for ion emission. The implications with regard to the UV laser ablation of hydrated environmental and biological minerals are discussed.

  8. Electron Photodetachment from Aqueous Anions. I. Quantum Yields for Generation of Hydrated Electron by 193 and 248 nm Laser Photoexcitation of Miscellaneous Inorganic Anions

    CERN Document Server

    Sauer, M C; Shkrob, I A; Sauer, Myran C.; Shkrob, Ilya A.

    2004-01-01

    Time resolved transient absorption spectroscopy has been used to determine quantum yields for electron photodetachment in 193 nm and (where possible) 248 nm laser excitation of miscellaneous aqueous anions, including hexacyanoferrate(II), sulfate, sulfite, halide anions (Cl-, Br-, and I-), pseudohalide anions (OH-, HS-, CNS-), and several common inorganic anions for which no quantum yields have been reported heretofore: SO3=, NO2-, NO3-, ClO3- and ClO4-. Molar extinction coefficients for these anions and photoproducts of electron detachment from these anions at the excitation wavelengths were also determined. These results are discussed in the context of recent ultrafast kinetic studies and compared with the previous data obtained by product analyses. We suggest using electron photodetachment from the aqueous halide and pseudohalide anions as actinometric standard for time-resolved studies of aqueous photosystems in the UV.

  9. Ada Compiler Validation Summary Report: Certificate Number: 890119A1. 10032 Alsys AlsyCOMP 019, Version 4.1 Zenith Z-248 Model 50 and Intel isBC 286/12 Single Board Computer

    Science.gov (United States)

    1989-01-19

    Zenith Z-248 Model 50 under MS/DOS, Version 3.2 (host) to Intel isBC 286/12 single board computer (target), ACVC 1.10 g0 01 03 004 DD tŘ 1473 1DITION...Intel isBC 286/12 single board computer Completion of On-Site Testing: 19 January 1989 AcCesion For DTIC Tii prepared BY: . AFNOR .,ltir...Number: 890119A1.10032 Host: Zenith Z-248 Model 50 under MS/DOS, Version 3.2 Target: Intel isBC 286/12 single board computer Testing Completed 19 January

  10. Effects of temperature on the p53-DNA binding interactions and their dynamical behavior: comparing the wild type to the R248Q mutant.

    Directory of Open Access Journals (Sweden)

    Khaled Barakat

    Full Text Available BACKGROUND: The protein p53 plays an active role in the regulation of cell cycle. In about half of human cancers, the protein is inactivated by mutations located primarily in its DNA-binding domain. Interestingly, a number of these mutations possess temperature-induced DNA-binding characteristics. A striking example is the mutation of Arg248 into glutamine or tryptophan. These mutants are defective for binding to DNA at 310 K although they have been shown to bind specifically to several p53 response elements at sub-physiological temperatures (298-306 K. METHODOLOGY/PRINCIPAL FINDINGS: This important experimental finding motivated us to examine the effects of temperature on the structure and configuration of R248Q mutant and compare it to the wild type protein. Our aim is to determine how and where structural changes of mutant variants take place due to temperature changes. To answer these questions, we compared the mutant to the wild-type proteins from two different aspects. First, we investigated the systems at the atomistic level through their DNA-binding affinity, hydrogen bond networks and spatial distribution of water molecules. Next, we assessed changes in their long-lived conformational motions at the coarse-grained level through the collective dynamics of their side-chain and backbone atoms separately. CONCLUSIONS: The experimentally observed effect of temperature on the DNA-binding properties of p53 is reproduced. Analysis of atomistic and coarse-grained data reveal that changes in binding are determined by a few key residues and provide a rationale for the mutant-loss of binding at physiological temperatures. The findings can potentially enable a rescue strategy for the mutant structure.

  11. Oxalyl chloride, ClC(O)C(O)Cl: UV/vis spectrum and Cl atom photolysis quantum yields at 193, 248, and 351 nm.

    Science.gov (United States)

    Ghosh, Buddhadeb; Papanastasiou, Dimitrios K; Burkholder, James B

    2012-10-28

    Oxalyl chloride, (ClCO)(2), has been used as a Cl atom photolytic precursor in numerous laboratory kinetic and photochemical studies. In this study, the UV/vis absorption spectrum of (ClCO)(2) and the Cl atom quantum yields in its photolysis at 193, 248, and 351 nm are reported. The UV∕vis spectrum was measured between 200 and 450 nm at 296 K using diode array spectroscopy in conjunction with an absolute cross section obtained at 213.9 nm. Our results are in agreement with the spectrum reported by Baklanov and Krasnoperov [J. Phys. Chem. A 105, 97-103 (2001)], which was obtained at 11 discrete wavelengths between 193.3 and 390 nm. Cl atom quantum yields, Φ(λ), were measured using pulsed laser photolysis coupled with time resolved atomic resonance fluorescence detection of Cl. The UV photolysis of (ClCO)(2) has been shown in previous studies to occur via an impulsive three-body dissociation mechanism, (COCl)(2) + hv → ClCO* + Cl + CO (2), where the excited ClCO radical, ClCO*, either dissociates or stabilizes ClCO* → Cl + CO (3a), → ClCO (3b). ClCO is thermally unstable at the temperatures (253-298 K) and total pressures (13-128 Torr) used in our experiments ClCO + M → Cl + CO + M (4) leading to the formation of a secondary Cl atom that was resolvable in the Cl atom temporal profiles obtained in the 248 and 351 nm photolysis of (ClCO)(2). Φ(193 nm) was found to be 2.07 ± 0.37 independent of bath gas pressure (25.8-105.7 Torr, N(2)), i.e., the branching ratio for channel 2a or the direct formation of 2Cl + 2CO in the photolysis of (ClCO)(2) is >0.95. At 248 nm, the branching ratio for channel 2a was determined to be 0.79 ± 0.15, while the total Cl atom yield, i.e., following the completion of reaction (4), was found to be 1.98 ± 0.26 independent of bath gas pressure (15-70 Torr, N(2)). Φ(351 nm) was found to be pressure dependent between 7.8 and 122.4 Torr (He, N(2)). The low-pressure limit of the total Cl atom quantum yield, Φ(0)(351 nm), was 2

  12. Direct evidence for preferential {beta} C-H bond cleavage resulting from 248 nm photolysis of the n-propyl radical using selectively-deuterated 1-bromopropane precursors

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Z.; Mathews, M.G.; Koplitz, B. [Tulane Univ., New Orleans, LA (United States)

    1995-05-04

    A series of selectively deuterated 1-bromopropane precursors have been used to study site-specific photolysis in the n-propyl radical. A two-color photolysis approach (222 nm followed by 248 nm radiation) is used to create an intermediate photofragment and produce an H or a D atom, which is detected by 1 + 1 resonance ionization through Lyman-{alpha}. Target precursors are BrCH{sub 2}CD{sub 2}CD{sub 3}, BrCD{sub 2}CH{sub 2}CD{sub 3}, and BrCD{sub 2}CD{sub 2}CH{sub 3} as well as BrCD{sub 2}CH{sub 2}CH{sub 3}, BrCH{sub 2}CD{sub 2}CH{sub 3}, and BrCH{sub 2}CH{sub 2}CD{sub 3}. The `enhanced` H (or D) atom signals clearly demonstrate that C-H (or C-D) bond cleavage at the {beta} position is strongly favored. The net enhancement process undoubtedly involves photolysis of an intermediate, almost certainly the n-propyl radical. A comparison with systems involving ethyl and isopropyl radical photolysis is also presented. 14 refs., 4 figs.

  13. 基于PIC18F248的RS232/CAN互连适配器的设计及实现%The Design and Realization of Interconnected Adapter Between RS232 and CAN Bus Based on PIC18F248 Microcomputer

    Institute of Scientific and Technical Information of China (English)

    陈彪; 毛六平; 戴瑜兴

    2004-01-01

    为了将变电站综合自动化系统中具有RS232接口的继电保护器接入到CAN通信网络中,设计了一种基于PIC18F248的RS232/CAN互连适配器,对其硬件接口电路、硬件抗干扰电路和CAN报文帧以及单片机软件流程的设计与实现进行了叙述.该互连适配器已成功应用于以RS232作为通信接口的继电保护器上,位速率高,通信稳定可靠,具有较强的抗干扰能力.

  14. Characterization of the in vitro expressed autoimmune rippling muscle disease immunogenic domain of human titin encoded by TTN exons 248-249

    Energy Technology Data Exchange (ETDEWEB)

    Zelinka, L. [Biomedical Sciences Program, Kent State University, Kent, OH (United States); McCann, S.; Budde, J.; Sethi, S.; Guidos, M.; Giles, R. [Center for Applied Chemical Biology, Department of Biological Sciences, Youngstown State University, One University Plaza, Youngstown, OH 44555 (United States); Walker, G.R., E-mail: grwalker@ysu.edu [Center for Applied Chemical Biology, Department of Biological Sciences, Youngstown State University, One University Plaza, Youngstown, OH 44555 (United States); Biomedical Sciences Program, Kent State University, Kent, OH (United States)

    2011-08-05

    Highlights: {yields} Affinity purification of the autoimmune rippling muscle disease immunogenic domain of titin. {yields} Partial sequence analysis confirms that the peptides is in the I band region of titin. {yields} This region of the human titin shows high degree of homology to mouse titin N2-A. -- Abstract: Autoimmune rippling muscle disease (ARMD) is an autoimmune neuromuscular disease associated with myasthenia gravis (MG). Past studies in our laboratory recognized a very high molecular weight skeletal muscle protein antigen identified by ARMD patient antisera as the titin isoform. These past studies used antisera from ARMD and MG patients as probes to screen a human skeletal muscle cDNA library and several pBluescript clones revealed supporting expression of immunoreactive peptides. This study characterizes the products of subcloning the titin immunoreactive domain into pGEX-3X and the subsequent fusion protein. Sequence analysis of the fusion gene indicates the cloned titin domain (GenBank ID: (EU428784)) is in frame and is derived from a sequence of N2-A spanning the exons 248-250 an area that encodes the fibronectin III domain. PCR and EcoR1 restriction mapping studies have demonstrated that the inserted cDNA is of a size that is predicted by bioinformatics analysis of the subclone. Expression of the fusion protein result in the isolation of a polypeptide of 52 kDa consistent with the predicted inferred amino acid sequence. Immunoblot experiments of the fusion protein, using rippling muscle/myasthenia gravis antisera, demonstrate that only the titin domain is immunoreactive.

  15. Photodissociation of gaseous CH{sub 3}COSH at 248 nm by time-resolved Fourier-transform infrared emission spectroscopy: Observation of three dissociation channels

    Energy Technology Data Exchange (ETDEWEB)

    Hu, En-Lan; Tsai, Po-Yu; Fan, He; Lin, King-Chuen [Department of Chemistry, National Taiwan University, Taipei 106, Taiwan (China) and Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan (China)

    2013-01-07

    Upon one-photon excitation at 248 nm, gaseous CH{sub 3}C(O)SH is dissociated following three pathways with the products of (1) OCS + CH{sub 4}, (2) CH{sub 3}SH + CO, and (3) CH{sub 2}CO + H{sub 2}S that are detected using time-resolved Fourier-transform infrared emission spectroscopy. The excited state {sup 1}(n{sub O}, {pi}{sup *}{sub CO}) has a radiative lifetime of 249 {+-} 11 ns long enough to allow for Ar collisions that induce internal conversion and enhance the fragment yields. The rate constant of collision-induced internal conversion is estimated to be 1.1 Multiplication-Sign 10{sup -10} cm{sup 3} molecule{sup -1} s{sup -1}. Among the primary dissociation products, a fraction of the CH{sub 2}CO moiety may undergo further decomposition to CH{sub 2}+ CO, of which CH{sub 2} is confirmed by reaction with O{sub 2} producing CO{sub 2}, CO, OH, and H{sub 2}CO. Such a secondary decomposition was not observed previously in the Ar matrix-isolated experiments. The high-resolution spectra of CO are analyzed to determine the ro-vibrational energy deposition of 8.7 {+-} 0.7 kcal/mol, while the remaining primary products with smaller rotational constants are recognized but cannot be spectrally resolved. The CO fragment detected is mainly ascribed to the primary production. A prior distribution method is applied to predict the vibrational distribution of CO that is consistent with the experimental findings.

  16. Incidence and clinical characteristics of unexpected uterine sarcoma after hysterectomy and myomectomy for uterine fibroids: a retrospective study of 10,248 cases

    Directory of Open Access Journals (Sweden)

    Zhao WC

    2015-10-01

    Full Text Available Wan-Cheng Zhao,1 Fang-Fang Bi,1 Da Li,2 Qing Yang11Department of Obstetrics and Gynecology, 2Center of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of ChinaBackground: Uterine fibroids often require a hysterectomy or myomectomy via laparotomy or laparoscopy. Morcellation is often necessary to perform a laparoscopic surgery. The objective of this study is to determine the incidence of unexpected uterine sarcomas (UUSs after hysterectomy and myomectomy for uterine fibroids and to reduce the occurrence and avoid the morcellation of UUSs by analyzing their characteristics.Methods: Women who had a hysterectomy or myomectomy for uterine fibroids in Shengjing Hospital of China Medical University between November 2008 and November 2014 were selected for the study, and their clinical characteristics were analyzed.Results: During the period, 48 UUSs were found in 10,248 cases, and the overall incidence was 0.47%. There was no statistical difference (P=0.449 regarding the incidence (0.50% vs 0.33% between 42 UUSs in 8,456 cases undergoing laparotomy and six UUSs in 1,792 cases undergoing laparoscopy. Most of the UUSs were stage I (89.58%, which occurred more commonly (56.25% in women aged 40–49. Abnormal uterine bleeding (39.58% was the main clinical manifestation. Rapidly growing pelvic masses (12.5%, rich blood flow signals (18.75%, and degeneration of uterine fibroids (18.75% prompted by ultrasonography may suggest the possibility of UUSs. The margins of most UUSs (93.75% were regular, which may cause UUSs to be misdiagnosed as uterine fibroids. Fifteen cases underwent magnetic resonance imaging examinations. Approximately 73.33% showed heterogeneous and hypointense signal intensity on T1-weighted images, and 80% showed intermediate-to-high signal intensity on T2-weighted images, with necrosis and hemorrhage in 40% of cases. After contrast administration, 80% presented early heterogeneous

  17. Paired observation of californium-252 neutron intraluminal brachytherapy combined with external-beam radiotherapy with and without lead shielding for cervical cancer%252 Cf中子腔内照射结合挡铅与不挡铅外照射治疗宫颈癌的配对观察

    Institute of Scientific and Technical Information of China (English)

    戴卓捷; 雷新; 陈永红; 刘佳

    2015-01-01

    目的:比较252 Cf中子腔内照射结合挡铅盆腔对穿野和不挡铅箱式四野外照射治疗宫颈癌的治疗结果。方法2004—2007年本院收治的Ⅱa—Ⅲb 期的宫颈鳞癌患者,按照临床分期、年龄、肿瘤大小、贫血程度为配对条件,共筛选出26对(52例)研究对象,分为挡铅盆腔对穿野组(挡铅组)和不挡铅箱式四野组(不挡铅组)。两组患者外照射期间穿插252 Cf中子后装治疗。 Kaplan?Meier法计算5年LC、OS、DFS 并 Logrank 检验差异,晚期并发症发生率差异行 McNemar 法检验。结果挡铅、不挡铅组5年LC 率分别为85%、81%(P=0??014),OS 率分别为89%、73%(P=0??013),DFS 率分别为89%、73%(P=0??013),晚期并发症发生率分别为12%、23%(P=0??008)。结论腔内照射结合外照射治疗宫颈癌时无论采取对穿野还是箱式四野,后程前后野中央均应挡铅。%Objective To compare the efficacy between californium?252 ( 252 Cf ) neutron intraluminal brachytherapy combined with external?beam radiotherapy with lead?shielding pelvic parallel opposing field technique and non?lead?shielding four?field box technique for cervical cancer. Methods A total of 52 patients with stage Ⅱa?Ⅲb cervical squamous cell carcinoma who were admitted to our hospital from 2004 to 2007 were enrolled as subjects and paired by clinical stage, age, tumor size, and degree of anemia. The 26 pairs of patients were divided into lead?shielding pelvic parallel opposing field group (lead?shielding group) and non?lead?shielding four?field box group (non?lead?shielding group). For all patients in both groups, 252 Cf neutron brachytherapy was added in external?beam radiotherapy. The local control (LC), overall survival (OS), and disease?free survival (DFS) rates were calculated using the Kaplan?Meier method and analyzed using the log?rank test. The difference in the incidence of late complications was

  18. Attempts to produce superheavy elements by fusion of /sup 48/Ca with /sup 248/Cm in the bombarding energy range of 4. 5--5. 2 MeV/u

    Energy Technology Data Exchange (ETDEWEB)

    Armbruster, P.; Agarwal, Y.K.; Bruechle, W.; Bruegger, M.; Dufour, J.P.; Gaggeler, H.; Hessberger, F.P.; Hofmann, S.; Lemmertz, P.; Muenzenberg, G.; Poppensieker, K.; Reisdorf, W.; Schadel, M.; Schmidt, K.; Schneider, J.H.R.; Schneider, W.F.W.; Suemmerer, K.; Vermeulen, D.; Wirth, a.G.; Ghiorso, A.; Gregorich, K.E.; Lee, D.; Leino, M.; Moody, K.J.; Seaborg, G.T.; Welch, R.B.; Wilmarth, P.; Yashita, S.; Frink, C.; Greulich, N.; Herrmann, G.; Hickmann, U.; Hildebrand, N.; Kratz, J.V.; Trautman, N.; Fowler, M.M.; Hoffman, D.C.; Daniels, W.R.; von Gunten, H.R.; Dornhoefer, H.

    1985-02-04

    A search for superheavy elements was made in bombardments of /sup 248/Cm with /sup 48/Ca ions performed at projectile energies close to the interaction barrier in order to keep the excitation energy of the compound nucleus Z = 116, A = 296 as low as possible. No evidence for superheavy nuclei was obtained in a half-life region from 1 ..mu..s to 10 yr with a production cross section greater than 10/sup -34/ to 10/sup -35/ cm/sup 2/. .AE

  19. 南阳市中心医院门诊西药房248例药物咨询情况分析%ANALYSIS OF PHARMACEUTICAL CONSULTATION SERVICE OF 248 CASES IN THE OUTPATIENT.PHARMACY IN THE CENTER HOSPITAL OF NANYANG

    Institute of Scientific and Technical Information of China (English)

    魏简汇

    2011-01-01

    [目的]探讨本院门诊西药房的药物咨询情况,总结咨询内容,提高我院药学服务质量,为更好的指导临床工作提供依据.[方法]对我院2009年7~12月门诊西药房248例药物的咨询情况进行回顾性分析,对咨询的药物类型、咨询内容进行统计分析.[结果]咨询药物的不良反应、药物之间的相互作用、用法用量的比例较高,分别占33.06%、27.42%、20.16%;咨询的药物类型排序前3位的分别为心脑血管系统药物、呼吸系统药物、中枢神经系统药物,分别占26.61%、20.16%、17.74%.[结论]药物咨询服务是临床药学工作的重要组成部分,也是提高药学服务的重要环节,同时药物咨询对于提高患者的用药安全性及提高药师的知识水平具有重要的作用.%[Objective]To investigate the hospital outpatient pharmacy drug consultation, summarize the consultation content and improve the quality of service in our hospital pharmacy, so that to provide a better basis for clinical work.[Methods]248 cases were collected in our hospital from July 2009 to December 2009 in the outpatient pharmacy, and we retrospectively analyzed the consultation, the types of medicines device on the consultation content for statistical analysis.[Results]The rates of the consulting adverse drug reactions, drug interactions and dosage showed to be high, and accounted for 33.06%, 27.42% and 20.16%, respectively; The top 3 consultation drug types were cardiovascular system drugs, respiratory system agents and central nervous system drugs, and accounted for 26.61%, 20.16% and 17.74%, respectively.[Conclusion]Clinical Pharmacy drug counseling service is an important part of the work, and also an important part of improving pharmaceutical care, drug counseling plays an important role in improving the patient medication safety and the level of knowledge of pharmacists.

  20. Comparación de variables físicas, culinarias y amilográficas del cultivar de arroz (Oryza sativa L. MD248 con dos cultivares comerciales de arroz en Venezuela

    Directory of Open Access Journals (Sweden)

    Manuel Ávila

    2014-12-01

    Full Text Available El objetivo del estudio fue evaluar las variables físicas culinarias y amilográficas del cultivar MD248 y su potencial como arroz de mesa en Venezuela. Para ello, MD248 se sembró bajo un diseño completamente aleatorizado, en Calabozo (Estado Guárico, Venezuela, junto con 2 cultivares empleados como testigos de buena (D-Sativa y baja (D-Primera calidad culinaria. De cada cultivar se cosecharon 2.500 g de arroz paddy y se procesaron hasta obtener una fracción de arroz entero pulido la cual fue evaluada para: largo, ancho, espesor, relación largo/ancho (L/A, peso de 100 granos, contenido de amilosa aparente, tiempo de cocción, relación de expansión volumétrica (REV, relación de absorción de agua (RAA, viscosidades pico, media, final, ‘breakdown’, ‘setback’, consistencia y temperatura de empaste del perfil amilográfico. Además, atributos sensoriales descriptivos (brillo, percepción visual de la adhesividad, adhesividad manual, adhesividad entre los granos y preferenciales (apariencia, adhesividad, calidad global del arroz cocido. Los resultados indicaron diferencias estadísticas altamente significativas (p ≤ 0,01 entre los cultivares para largo, relación L/A, peso de 100 granos, contenido de amilosa aparente, tiempo de cocción, REV, RAA y todas las variables amilográficas, excepto para viscosidad media y temperatura de empaste (p > 0,05. En los perfiles descriptivo y preferencial hubo diferencias altamente significativas (p ≤ 0,01 para todos los atributos evaluados. MD248 estuvo asociado con los mayores valores de largo de grano (7,07 mm, relación L/A (3,43, peso de 100 granos (2,20 g y amilosa aparente (19,14 %, y con los menores valores de tiempo de cocción (22,90 min, REV (3,07, RAA (1,55, viscosidad pico (159,61 RVU, media (130,10 RVU, p > 0,05 y ‘breakdown’ (29,51 RVU. MD248 presentó un perfil descriptivo comparable al cultivar de buena calidad culinaria y se diferenció ampliamente del cultivar de baja

  1. Experimental Cross Sections for Reactions of Heavy Ions and 208Pb, 209Bi, 238U, and 248Cm Targets

    Energy Technology Data Exchange (ETDEWEB)

    Patin, Joshua Barnes [Univ. of California, Berkeley, CA (United States)

    2002-01-01

    The study of the reactions between heavy ions and 208Pb, 209Bi, 238U, and 248Cm Cm targets was performed to look at the differences between the cross sections of hot and cold fusion reactions. Experimental cross sections were compared with predictions from statistical computer codes to evaluate the effectiveness of the computer code in predicting production cross sections. Hot fusion reactions were studied with the MG system, catcher foil techniques and the Berkeley Gas-filled Separator (BGS). 3n- and 4n-exit channel production cross sections were obtained for the 238U(18O,xn)256-xFm, 238U(22Ne,xn)260-xNo, and 248Cm(15N,xn)263-xLr reactions and are similar to previous experimental results. The experimental cross sections were accurately modeled by the predictions of the HIVAP code using the Reisdorf and Schaedel parameters and are consistent with the existing systematics of 4n exit channel reaction products. Cold fusion reactions were examined using the BGS. The 48Pb(238Ca,xn)256-xNo, 208Pb(50Ti,xn)258-xRf, 208Pb(51V,xn)259-xDb, 50Bi(238Ti,xn)259-xDb, and 209Bi(51V,xn)260-xSg reactions were studied. The experimental production cross sections are in agreement with the results observed in previous experiments. It was necessary to slightly alter the Reisdorf and Schaedel parameters for use in the HIVAP code in order to more accurately model the experimental data. The cold fusion experimental results are in agreement with current 1n- and 2n-exit channel systematics.

  2. 7 CFR 248.2 - Definitions.

    Science.gov (United States)

    2010-01-01

    ..., training, monitoring, auditing, the development of and accountability for coupon and market management... who assemble at a defined location for the purpose of selling their produce directly to consumers... relationships between nutrition and health, all in keeping with the individual's personal, cultural,...

  3. 21 CFR 558.248 - Erythromycin thiocyanate.

    Science.gov (United States)

    2010-04-01

    ... considerations. The levels of antibiotic are expressed in terms of erythromycin master standard. One gram of... 18.5 Chickens; growth promotion and feed efficiency ,061623 (ii) 9.25 to 18.5 Turkeys; growth... (9.25) Starter ration for animals up to 35 lb body weight 061623 (iv) 18.5 Laying chickens; aids...

  4. BDML Metadata: 248 [SSBD[Archive

    Lifescience Database Archive (English)

    Full Text Available r, Laboratory for Developmental Dynamics See details in Kyoda et al. (2013) Nucleic Acids Res 41, D732-D737. CC BY-NC-SA 0.150 5d3e...l/Ce_KK_P002.pdpml0.05.xml http://ssbd.qbic.riken.jp/search/5d3ecffc-66f6-44eb-8f4c-7730fd0e51eb/ http://ssbd.qbic.riken.jp/omero/webclient/?show=dataset-203 ...

  5. 24 CFR 248.420 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... nonprofit organization (including a quasi-public organization) or a State or local housing agency that: (1.... Community-based nonprofit housing developer means a nonprofit community development corporation that: (1...-county level; and (5) In the case of a corporation acquiring eligible low income housing under subpart...

  6. 17 CFR 248.120 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... trust, general or limited partnership, association, or similar organization. (f) Concise—(1) In general... disclosures required or authorized by Federal or State law. (g) Consumer means an individual. (h) Control of a... communication of which would be a consumer report if the exclusions from the definition of “consumer report”...

  7. 7 CFR 248.4 - State Plan.

    Science.gov (United States)

    2010-01-01

    ... farmers' markets. (5) Outline of administrative staff and job descriptions. (6) Detailed description of... necessary to operate the FMNP. (4) Description of how the Program will achieve its dual purposes of... description of the financial management system, including, but not limited to documentation of how the...

  8. Reference: 248 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available lopment in maintaining the integrity of organs via cell-cell adhesion, thereby providing mechanical streng...th and facilitating the movement of metabolites throughout the plant. Cell adhesion

  9. Women: The Fifth World. Headline Series 248.

    Science.gov (United States)

    Boulding, Elise

    The document addresses past, present, and future issues concerning women througout the world. It is presented in seven chapters. Chapter I discusses women as the invisible "fifth world." The author contends that this fifth world exists, uncounted and unassisted, on every continent. Chapter II traces the role of women throughout history. The…

  10. 17 CFR 248.3 - Definitions.

    Science.gov (United States)

    2010-04-01

    ...) Avoid legal and highly technical business terminology whenever possible; and (F) Avoid explanations that... Exchange Commission. (f) Company means any corporation, limited liability company, business trust, general... business of which is engaging in activities that are financial in nature or incidental to such...

  11. 7 CFR 248.19 - Investigations.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Monitoring and Review of State..., where appropriate, a review of pertinent practices and policies of any State and local agency,...

  12. QTL Information Table: 248 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available ntitative characters in rice using RFLP markers. Euphytica V89, 349-354. http://dx.doi.org/10.1007/BF00022292 ... ...ant RFLP C)Interval F2 Palawan IR42 A RG143 RG214 pha Wu, P., Zhang, G., and Huang, N. (1996). Identification of QTLs controlling qua

  13. 7 CFR 248.7 - Nondiscrimination.

    Science.gov (United States)

    2010-01-01

    ... denied benefits, or be otherwise subjected to discrimination, under the FMNP. Because racial and ethnic... that the WIC data collection effort is sufficient to fulfill the racial/ethnic data collection... Rehabilitation Act of 1973, the Age Discrimination Act of 1975, Department of Agriculture regulations...

  14. Development of the Broadband and Dual-band Cavity Mirrors for SR-FEL at 355nm and 248nm%SR-FEL宽带腔镜与双带腔镜光学膜系实验研究与研制

    Institute of Scientific and Technical Information of China (English)

    高怀林; 王乃彦; 王东蕾; 王永

    2007-01-01

    利用"电子束蒸发沉积薄膜生长技术+离子束溅射沉积薄膜生长技术"、"HfO2/SiO2+Al2O3/SiO2+M-SiO2"复合光学膜系设计技术、400℃×4h高温处理技术,研制的SR-FEL宽带腔镜光学膜系在355nm中心波长的绝对光学反射率测量值为R(355nm)=99.45%,反射光谱带宽测量值为△λ(R≥99.00%)=75nm;研制的355nm/248nm双带腔镜光学膜系,在355nm中心波长,其绝对光学反射率测量值为R(355nm)=99.69%,反射光谱带宽测量值为△λ(R≥99.00%)=59nm;在248nm中心波长,R(248nm)=98.21%,绝对光学反射率光谱带宽测量值△λ(R≥99.00)=9mm,△λ(R≥98.00%)=33nm.

  15. EFFICACY OF BUPRENORPHINE HYDROCHLORIDE ON RELAPSE-PREVENTION AMONG HERION DEPENDENT PATIENTS AFTER DETOXIFICATION——248 CASES ON BUPRENORPHINE MAINTENANCE TREATMENT%盐酸丁丙诺啡对海洛因依赖者脱毒后预防复吸的研究——248例盐酸丁丙诺啡维持治疗临床研究

    Institute of Scientific and Technical Information of China (English)

    黄威巍; 徐荣海

    2006-01-01

    目的:研究盐酸丁丙诺啡对海洛因依赖者脱毒后预防复吸的效能.方法:248例海洛因依赖者完成脱毒后给予盐酸丁丙诺啡舌下含片维持治疗,药物剂量从第1月4 mg·d-1,2 mg·d-1到第2月后一直以1.5 mg·d-1维持;维持者每次来所取药时做尿液吗啡检测,填写相关量表.结果:丁丙诺啡舌下含片维持治疗第1,3,6,12,18,24月时的保持率分别为61.69%,29.84%,12.10%,2.65%,1.61%和0.81%.尿液吗啡检测阴性率在前2个月占应检人数的75%以上;渴求强度"非常想"和"不想"因子在第1,6,12月时差异有显著性(P<0.01);稽延性戒断症状总平均分第1月和第3,6,12月比较差异有显著性(P<0.01);不良反应以思睡、便秘为主,后者随维持治疗时间延长而加重.结论:盐酸丁丙诺啡舌下含片维持治疗对海洛因依赖者脱毒后预防复吸有肯定的作用.

  16. Time Series Analysis For The Californium Source In Sudbury Neutrino Observatory

    CERN Document Server

    Labranche, H

    2004-01-01

    The Sudbury Neutrino Observatory uses a 252Cf source to measure the neutron detection efficiency of its detector. We propose a method, the Time Series Analysis, that uses pairs of time intervals between the detected events to find the neutron detection efficiency, the probability to detect from a fission the prompt γ-rays, the neutron mean life inside the detector, the source fission rate and the residual activity rate from non-fission events. We explain our theoretical model of the source and the procedure to fit the data. With a 2.5 MeV threshold cut on the data, the neutron mean life is 5.281 ± 0.004(stat) msec and the source fission rate at June 12, 2001 is 4.360 ± 0.004(stat) sec −1. At this moment, the Time Series can only be applied to data when the source is near the centre. The technique is also applied with an AmBe source. We also show the latest progress to improve the technique. Finally, we briefly show another method, the Multiplicity Analysis, which was ...

  17. Design and Potentials of the Californium-252 Radiation Facility at WES

    Science.gov (United States)

    1975-09-01

    standards, using an Image Quality Indicator (IQI) and also a Beam Purity Indicator (BPI),** shows a relatively good thermal and epithermal neutron ...colli-nated beam of the desired neutron radiation. Consideration of the basic nuclear properties was therefore a necessity in achieving the desired...The upper 6 ft has been designed for use in radiography and neutron counting. The steel tank was prefabricated in two sections. The lower 6-ft

  18. Design of a californium-based epithermal neutron beam for neutron capture therapy.

    Science.gov (United States)

    Yanch, J C; Kim, J K; Wilson, M J

    1993-08-01

    The potential of the spontaneously fissioning isotope, 252Cf, to provide epithermal neutrons for use in boron neutron capture therapy (BNCT) has been investigated using Monte Carlo simulation. The Monte Carlo code MCNP was used to design an assembly composed of a 26 cm long, 11 cm radius cylindrical D2O moderator followed by a 64 cm long Al filter. Lithium filters are placed between the moderator and the filter and between the Al and the patient. A reflector surrounding the moderator/filter assembly is required in order to maintain adequate therapy flux at the patient position. An ellipsoidal phantom composed of skull- and brain-equivalent material was used to determine the dosimetric effect of this beam. It was found that both advantage depths and advantage ratios compare very favourably with reactor and accelerator epithermal neutron sources. The dose rate obtainable, on the other hand, is 4.1 RBE cGy min-1, based on a very large (1.0 g) source of 252Cf. This dose rate is two to five times lower than those provided by existing reactor beams and can be viewed as a drawback of using 252Cf as a neutron source. Radioisotope sources, however, do offer the advantage of in-hospital installation.

  19. 1935 15' Quad #248 Aerial Photo Mosaic Index

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  20. Dicty_cDB: VSD248 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Acid sequence rvrnplysceifrhhqneilsclplsflirqcqrclshqdfticwc*s*ccscriclqri rr*rrpslncrr*i*swfscrcrrpscchlccp...GL FD*kdn*yeqtiirmligsfl*yl*kek*k Translated Amino Acid sequence (All Frames) Frame A: rvrnplysceifrhhqneils...qksc*rekrrirrrygygf irlkrqli*anyy*NAYRQFPIVFIKRKIKKNKNIKKK--- ---qsfifveifrhhqneilsclplsflirqcqrclshqdfticwc

  1. Dicty_cDB: CFC248 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 576997 |BQ576997.1 PfESToab12e02.y1 Plasmodium falciparum 3D7 asexual cDNA Plasmodium falciparum cDNA 5' sim...ce. 54 2e-07 3 BU497494 |BU497494.1 PfESToab64b06.y1 Plasmodium falciparum 3D7 asexual cDNA Plasmodium falci...:Q19130 Q19130 F07A11.2 PROTEIN. [1] ;, mRNA sequence. 36 7e-04 3 BU496736 |BU496736.1 PfESToab58b09.y1 Plasmodium falciparum 3D7 ase...xual cDNA Plasmodium falciparum cDNA 5' similar to SW:GLMS_SYNY3 P72720 GLUCOSAMINE

  2. 7 CFR 248.10 - Coupon and market management.

    Science.gov (United States)

    2010-01-01

    ... of 1972, section 504 of the Rehabilitation Act of 1973, the Age Discrimination Act of 1975, Department of Agriculture regulations on non-discrimination (7 CFR parts 15, 15a and 15b), and FNS... redeemed only for eligible foods; (iii) Provide eligible foods at the current price or less than...

  3. Laser sputtering of highly oriented pyrolytic graphite at 248 nm

    Science.gov (United States)

    Krajnovich, Douglas J.

    1995-01-01

    The interaction of excimer laser pulses with a highly oriented pyrolytic graphite (HOPG) target has been studied. HOPG, a close approximation to single crystal graphite, was irradiated along a freshly cleaved basal plane in vacuum by pulses from a KrF excimer laser. The energy fluence was varied between 300-700 mJ/cm2, resulting in material removal rates of plasma effects are minimized. Time-of-flight distributions of the neutral carbon atoms and small carbon clusters were measured and inverted to obtain translational energy flux distributions and relative sputtering yields as a function of fluence. The translational energy distributions are remarkably close to Maxwell-Boltzmann distributions over most of the fluence range studied. However, the mean translational energies are far too high to reconcile with a simple thermal vaporization model. For example, the mean translational energy of C3, the most abundant species, increases from 1.1 eV at 305 mJ/cm2 to 31.7 eV at 715 mJ/cm2. Explanations are considered for this curious mix of thermal and non-thermal behavior. At the high end of our fluence range, the mean translational energies of C1, C2, C3 converge to a 1:2:3 ratio, indicating that the velocity distributions are almost identical. This particular result can be interpreted as a gas dynamic effect. Prolonged sputtering of the same target spot results in a falloff in the sputtering yield and the mean translational energies, but little change in the cluster size distribution. These effects are related to impurity induced topography formation on the target surface.

  4. Dicty_cDB: CHD248 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SIPFHEFETMESSTTTTLLSENNGGGGGSSCNDNSRRNSLNILPLR LKSFSFSAPQSDSM--- ---TTTTTIPSPSTNSRSICNTLMDSTDSINNTNTNTNTNTNT...CNDNSRRNSLNILPLR LKSFSFSAPQSDSM--- ---TTTTTIPSPSTNSRSICNTLMDSTDSINNTNTNTNTNTNTNTNTNTNTNTNTNTNAN INNKVSTTTTTT

  5. Dicty_cDB: SFF248 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available PPDQQRLIFA G--- ---KRTPSPFSLKIKRXYANFC*tsxw*txplgsgr*l*h*kxqsqnpxqxrxsprsttf hfrw*tikkwpyxx*lqhpkxipxpfsxxikrwxanxcknlxw*xxpxgsxrf...xxx*kcq sqnsxqxrfsprstxixfxwxtikxwxdxxxlqxskgipxpfsxxxkrxxanxc*nxxr* nxpxgsrrx Transla...*fsl v--- ---KRTPSPFSLKIKRXYANFC*tsxw*txplgsgr*l*h*kxqsqnpxqxrxsprsttf hfrw*tikkwpyxx*lqhpkxipxpfsxxikrwxanxcknlxw*xxpxgsxrf...xxx*kcq sqnsxqxrfsprstxixfxwxtikxwxdxxxlqxskgipxpfsxxxkrxxanxc*nx

  6. Determination of the optimum-size californium-252 neutron source for borehole capture gamma-ray analysis

    Science.gov (United States)

    Senftle, F.E.; Macy, R.J.; Mikesell, J.L.

    1979-01-01

    The fast- and thermal-neutron fluence rates from a 3.7 ??g 252Cf neutron source in a simulated borehole have been measured as a function of the source-to-detector distance using air, water, coal, iron ore-concrete mix, and dry sand as borehole media. Gamma-ray intensity measurements were made for specific spectral lines at low and high energies for the same range of source-to-detector distances in the iron ore-concrete mix and in coal. Integral gamma-ray counts across the entire spectrum were also made at each source-to-detector distance. From these data, the specific neutron-damage rate, and the critical count-rate criteria, we show that in an iron ore-concrete mix (low hydrogen concentration), 252Cf neutron sources of 2-40 ??g are suitable. The source size required for optimum gamma-ray sensitivity depends on the energy of the gamma ray being measured. In a hydrogeneous medium such as coal, similar measurements were made. The results show that sources from 2 to 20 ??g are suitable to obtain the highest gamma-ray sensitivity, again depending on the energy of the gamma ray being measured. In a hydrogeneous medium, significant improvement in sensitivity can be achieved by using faster electronics; in iron ore, it cannot. ?? 1979 North-Holland Publishing Co.

  7. Optical transitions in highly charged californium ions with high sensitivity to variation of the fine-structure constant.

    Science.gov (United States)

    Berengut, J C; Dzuba, V A; Flambaum, V V; Ong, A

    2012-08-17

    We study electronic transitions in highly charged Cf ions that are within the frequency range of optical lasers and have very high sensitivity to potential variations in the fine-structure constant, α. The transitions are in the optical range despite the large ionization energies because they lie on the level crossing of the 5f and 6p valence orbitals in the thallium isoelectronic sequence. Cf(16+) is a particularly rich ion, having several narrow lines with properties that minimize certain systematic effects. Cf(16+) has very large nuclear charge and large ionization energy, resulting in the largest α sensitivity seen in atomic systems. The lines include positive and negative shifters.

  8. Keno-Nr a Monte Carlo Code Simulating the Californium -252-SOURCE-DRIVEN Noise Analysis Experimental Method for Determining Subcriticality

    Science.gov (United States)

    Ficaro, Edward Patrick

    The ^{252}Cf -source-driven noise analysis (CSDNA) requires the measurement of the cross power spectral density (CPSD) G_ {23}(omega), between a pair of neutron detectors (subscripts 2 and 3) located in or near the fissile assembly, and the CPSDs, G_{12}( omega) and G_{13}( omega), between the neutron detectors and an ionization chamber 1 containing ^{252}Cf also located in or near the fissile assembly. The key advantage of this method is that the subcriticality of the assembly can be obtained from the ratio of spectral densities,{G _sp{12}{*}(omega)G_ {13}(omega)over G_{11 }(omega)G_{23}(omega) },using a point kinetic model formulation which is independent of the detector's properties and a reference measurement. The multigroup, Monte Carlo code, KENO-NR, was developed to eliminate the dependence of the measurement on the point kinetic formulation. This code utilizes time dependent, analog neutron tracking to simulate the experimental method, in addition to the underlying nuclear physics, as closely as possible. From a direct comparison of simulated and measured data, the calculational model and cross sections are validated for the calculation, and KENO-NR can then be rerun to provide a distributed source k_ {eff} calculation. Depending on the fissile assembly, a few hours to a couple of days of computation time are needed for a typical simulation executed on a desktop workstation. In this work, KENO-NR demonstrated the ability to accurately estimate the measured ratio of spectral densities from experiments using capture detectors performed on uranium metal cylinders, a cylindrical tank filled with aqueous uranyl nitrate, and arrays of safe storage bottles filled with uranyl nitrate. Good agreement was also seen between simulated and measured values of the prompt neutron decay constant from the fitted CPSDs. Poor agreement was seen between simulated and measured results using composite ^6Li-glass-plastic scintillators at large subcriticalities for the tank of uranyl nitrate. It is believed that the response of these detectors is not well known and is incorrectly modeled in KENO-NR. In addition to these tests, several benchmark calculations were also performed to provide insight into the properties of the point kinetic formulation.

  9. Radiological Characterization Technical Report on Californium-252 Sealed Source Transuranic Debris Waste for the Off-Site Source Recovery Project at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, Alexander [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-04-24

    This document describes the development and approach for the radiological characterization of Cf-252 sealed sources for shipment to the Waste Isolation Pilot Plant. The report combines information on the nuclear material content of each individual source (mass or activity and date of manufacture) with information and data on the radionuclide distributions within the originating nuclear material. This approach allows for complete and accurate characterization of the waste container without the need to take additional measurements. The radionuclide uncertainties, developed from acceptable knowledge (AK) information regarding the source material, are applied to the summed activities in the drum. The AK information used in the characterization of Cf-252 sealed sources has been qualified by the peer review process, which has been reviewed and accepted by the Environmental Protection Agency.

  10. 17 CFR 248.15 - Other exceptions to notice and opt out requirements.

    Science.gov (United States)

    2010-04-01

    ... providers and joint marketing do not apply when you disclose nonpublic personal information: (1) With the... related to public safety; (5)(i) To a consumer reporting agency in accordance with the Fair Credit....7(f). Relation to Other Laws; Effective Date...

  11. Morphology of Copper Tin Sulfide Films Grown by Pulsed Laser Deposition at 248 and 355 nm

    DEFF Research Database (Denmark)

    Ettlinger, Rebecca Bolt; Cazzaniga, Andrea Carlo; Crovetto, Andrea;

    Thin films solar cells based on Cu2ZnSnS4 (CZTS) as absorber layer have seen a rapid development leading to a world record of 8.8% [1]. However, other p-type semiconductors with fewer elements and reduced complexity compared to CZTS are also available, such as ternary Cu–Sn–S systems, i.e. Cu2SnS3...

  12. SU-E-J-248: Contributions of Tumor and Stroma Phenotyping in Computer-Aided Diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Li, H; Lan, L; Sennett, C; Giger, M [Univ Chicago, Chicago, IL (United States)

    2015-06-15

    Purpose: To gain insight into the role of parenchyma stroma in the characterization of breast tumors by incorporating computerized mammographic parenchyma assessment into breast CADx in the task of distinguishing between malignant and benign lesions. Methods: This study was performed on 182 biopsy-proven breast mass lesions, including 76 benign and 106 malignant lesions. For each full-field digital mammogram (FFDM) case, our quantitative imaging analysis was performed on both the tumor and a region-of-interest (ROI) from the normal contralateral breast. The lesion characterization includes automatic lesion segmentation and feature extraction. Radiographic texture analysis (RTA) was applied on the normal ROIs to assess the mammographic parenchymal patterns of these contralateral normal breasts. Classification performance of both individual computer extracted features and the output from a Bayesian artificial neural network (BANN) were evaluated with a leave-one-lesion-out method using receiver operating characteristic (ROC) analysis with area under the curve (AUC) as the figure of merit. Results: Lesion characterization included computer-extracted phenotypes of spiculation, size, shape, and margin. For parenchymal pattern characterization, five texture features were selected, including power law beta, contrast, and edge gradient. Merging of these computer-selected features using BANN classifiers yielded AUC values of 0.79 (SE=0.03) and 0.67 (SE=0.04) in the task of distinguishing between malignant and benign lesions using only tumor phenotypes and texture features from the contralateral breasts, respectively. Incorporation of tumor phenotypes with parenchyma texture features into the BANN yielded improved classification performance with an AUC value of 0.83 (SE=0.03) in the task of differentiating malignant from benign lesions. Conclusion: Combining computerized tumor and parenchyma phenotyping was found to significantly improve breast cancer diagnostic accuracy highlighting the need to consider both tumor and stroma in decision making. Funding: University of Chicago Dean Bridge Fund, NCI U24-CA143848-05, P50-CA58223 Breast SPORE program, and Breast Cancer Research Foundation. COI: MLG is a stockholder in R2 technology/Hologic and receives royalties from Hologic, GE Medical Systems, MEDIAN Technologies, Riverain Medical, Mitsubishi, and Toshiba. MLG is a cofounder and stockholder in Quantitative Insights.

  13. Massimo De Giuseppe, La rivoluzione messicana, Bologna, Il Mulino, Universale Paperbacks, 2013, 248 p.

    OpenAIRE

    Traffano, Daniela

    2014-01-01

    Las conmemoraciones del bicentenario del proceso de Independencia y del centenario de la Revolución, que en México motivaron a lo largo del 2010 la difusión de discursos e imágenes, eventos políticos, culturales y deportivos así como la creación de espectáculos, videos y proyectos académicos, trascendieron el Atlántico y encontraron una voz y un espacio muy particulares en Italia, gracias a la última publicación del historiador Massimo De Giuseppe. Se trata de “La rivoluzione messicana”, un v...

  14. 27 CFR 24.248 - Processes authorized for the treatment of wine, juice, and distilling material.

    Science.gov (United States)

    2010-04-01

    ....2910. 1 This process must be done on distilled spirits plant premises. However, reverse osmosis, under... vinous character of the wine(2) None of the stripping solution may migrate into the wine. Reverse...

  15. Parameters optimization for biological molecules patterning using 248-nm ultrafast lasers

    Science.gov (United States)

    Dinca, V.; Ranella, A.; Popescu, A.; Dinescu, M.; Farsari, M.; Fotakis, C.

    2007-12-01

    Laser-induced forward transfer has been used for the deposition of photoactive biotin in micron-scale patterns. The process uses a 500 fs pulsed KrF laser beam to transfer small amounts of a liquid solution target as micron-size droplets to a substrate placed parallel and in close proximity to it. The biomolecules remain active after the transfer; this is demonstrated through fluorescence assays. In addition to the laser parameters, those regarding the target composition and the receiving surface for the miniaturization of the transferred patterns have been studied and optimized. Droplets as small as 5 μm have been obtained by reducing the target thickness and transfer energy; by increasing the percentage of glycerol added in the biomolecules solution and by using hydrophobic surfaces as receiving substrates. The influence of the glycerol addition and the hydrophobicity of the receiving surfaces on the activity of the transferred biomolecules have also been studied.

  16. 248: Resuscitative Endovascular Balloon Occlusion of the Aorta Improves Survival in Lethal Hemorrhage

    Science.gov (United States)

    2014-01-01

    cohort study with the data reported to the National Emergency Airway Registry for Children (NEAR4KIDS) from 7/2010 to 3/2014. CA was defined as CPR >1min...Patient characteristics include age, gender, indications, and history of difficult airway. Provider characteris- tics include training level, and...and none of the patients had a prior history of seizure disorders. NCSE occurred in 25% (3/12) of patients. Out of the nine patients who did not show

  17. 17 CFR 248.6 - Information to be included in privacy notices.

    Science.gov (United States)

    2010-04-01

    ...; (4) The categories of nonpublic personal information about your former customers that you disclose... personal information about your former customers, other than those parties to whom you disclose information... companies; and (iii) Others. (4) Disclosures under exception for service providers and joint marketers....

  18. 7 CFR 2.48 - Administrator, Rural Business-Cooperative Service.

    Science.gov (United States)

    2010-01-01

    ... of section 105(f) pertaining to the annual report to Congress; (vii) Section 109 of the Act (42 U.S.C... Alternative Agricultural Research and Commercialization Corporation and the funds in the Alternative Agricultural Research and Commercialization Fund in accordance with section 6201 of the Farm Security and...

  19. 49 CFR 24.8 - Compliance with other laws and regulations.

    Science.gov (United States)

    2010-10-01

    ...—Equal Employment Opportunity, as amended. (j) Executive Order 11625—Minority Business Enterprise. (k...—Leadership and Coordination of Non-Discrimination Laws. (m) Executive Order 12630—Governmental Actions and... Emergency Assistance Act, as amended (42 U.S.C. 5121 et seq.). (o) Executive Order 12892—Leadership...

  20. 26 CFR 1.248-1T - Election to amortize organizational expenditures (temporary).

    Science.gov (United States)

    2010-04-01

    ... irrevocable and applies to all organizational expenditures of the corporation. A change in the characterization of an item as an organizational expenditure is a change in method of accounting to which sections... as a change in method of accounting if the corporation amortized organizational expenditures for...

  1. Analysis of the endogenous peptide profile of milk: identification of 248 mainly casein-derived peptides.

    Science.gov (United States)

    Baum, Florian; Fedorova, Maria; Ebner, Jennifer; Hoffmann, Ralf; Pischetsrieder, Monika

    2013-12-06

    Milk is an excellent source of bioactive peptides. However, the composition of the native milk peptidome has only been partially elucidated. The present study applied matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) directly or after prefractionation of the milk peptides by reverse-phase high-performance liquid chromatography (RP-HPLC) or OFFGEL fractionation for the comprehensive analysis of the peptide profile of raw milk. The peptide sequences were determined by MALDI-TOF/TOF or nano-ultra-performance liquid chromatography-nanoelectrospray ionization-LTQ-Orbitrap-MS. Direct MALDI-TOF-MS analysis led to the assignment of 57 peptides. Prefractionation by both complementary methods led to the assignment of another 191 peptides. Most peptides originate from α(S1)-casein, followed by β-casein, and α(S2)-casein. κ-Casein and whey proteins seem to play only a minor role as peptide precursors. The formation of many, but not all, peptides could be explained by the activity of the endogenous peptidases, plasmin or cathepsin D, B, and G. Database searches revealed the presence of 22 peptides with established physiological function, including those with angiotensin-converting-enzyme (ACE) inhibitory, immunomodulating, or antimicrobial activity.

  2. 17 CFR 248.121 - Affiliate marketing opt out and exceptions.

    Science.gov (United States)

    2010-04-01

    ... business relationship with the consumer. (b) Making marketing solicitations—(1) In general. For purposes of... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Affiliate marketing opt out... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §...

  3. 24 CFR 248.221 - Approval of a plan of action that involves termination of low income affordability restrictions.

    Science.gov (United States)

    2010-04-01

    ... monthly rental payment in any year that exceeds the increase in the Consumer Price Index or 10 percent...); the Age Discrimination Act of 1975 (42 U.S.C. 6101-6107); section 504 of the Rehabilitation Act...

  4. 24 CFR 248.141 - Criteria for approval of a plan of action involving prepayment and voluntary termination.

    Science.gov (United States)

    2010-04-01

    ... Consumer Price Index or 10 percent (whichever is lower); or (ii) Involuntarily displace current tenants... Age Discrimination Act of 1975 (42 U.S.C. 6101-6107); section 504 of the Rehabilitation Act of...

  5. 248香茶菜属植物细胞毒成分研究概况

    Institute of Scientific and Technical Information of China (English)

    顾关云; 蒋昱

    2004-01-01

    对香茶菜属多种植物的化学和药理研究表明,一类具有特殊结构的贝壳杉烯二萜普遍存在于该属植物中,并大多具有抗肿瘤等生物活性.就近年来研究的腺花香荼菜等19种植物的化学成分与细胞毒活性作一概述.

  6. SU-E-T-248: Near Real-Time Analysis of Radiation Delivery and Imaging, Accuracy to Ensure Patient Safety

    Energy Technology Data Exchange (ETDEWEB)

    Wijesooriya, K; Seitter, K; Desai, V; Read, P; Larner, J [University of Virginia Health Systems, Charlottesville, VA (United States)

    2014-06-01

    Purpose: To develop and optimize an effective software method for comparing planned to delivered control point machine parameters for all VARIAN TrueBeam treatments so as to permit (1) assessment of a large patient pool throughout their treatment course to quantify treatment technique specific systematic and random uncertainty of observables, (2) quantify the site specific daily imaging shifts required for target alignment, and (3) define tolerance levels for mechanical parameters and imaging parameters based on statistical analysis data gathered, and the dosimetric impact of variations. Methods: Treatment and imaging log files were directly compared to plan parameters for Eclipse and Pinnacle planned treatments via 3D, IMRT, control point, RapidArc, and electrons. Each control point from all beams/arcs (7984) for all fractions (1940) of all patients treated over six months were analyzed. At each control point gantry angle, collimator angle, couch angle, jaw positions, MLC positions, MU were compared. Additionally per-treatment isocenter shifts were calculated. Results were analyzed as a whole in treatment type subsets: IMRT, 3D, RapidArc; and in treatment site subsets: brain, chest/mediastinum, esophagus, H and N, lung, pelvis, prostate. Results: Daily imaging isocenter shifts from initial external tattoo alignment were dependent on the treatment site with < 0.5 cm translational shifts for H and N, Brain, and lung SBRT, while pelvis, esophagus shifts were ∼1 cm. Mechanical delivery parameters were within tolerance levels for all sub-beams. The largest variations were for RapidArc plans: gantry angle 0.11±0.12,collimator angle 0.00±0.00, jaw positions 0.48±0.26, MLC leaf positions 0.66±0.08, MU 0.14±0.34. Conclusion: Per-control point validation reveals deviations between planned and delivered parameters. If used in a near real-time error checking system, patient safety can be improved by equipping the treatment delivery system with additional forcing functions which by-pass human error avenues.

  7. Investigation of the threshold intensity versus gas pressure in the breakdown of helium by 248 nm laser radiation

    Science.gov (United States)

    Gamal, Yosr E. E.-D.; Abdellatif, Galila

    2014-10-01

    An investigation of the unexpectedly strong dependence of the threshold intensity on the gas pressure in the experimental study on the breakdown of He by short laser wavelength (Turcu et al., in Opt Commun, 134:66-68, 1997) is presented. A modified electron cascade model is applied (Evans and Gamal, in J Phys D Appl Phys, 13:1447-1458, 1980). Computations revealed reasonable agreement between the calculated thresholds and the measured ones. Moreover, the calculated electron energy distribution function and its parameters proved that multiphoton ionization of ground and excited atoms is the main source for the seed electrons, which contributes to the breakdown of helium. The effect of diffusion losses over pressures <1,000 Torr elucidated the origin of the strong dependence of the threshold intensity on the gas pressure. Collisional ionization dominates only at high pressures. No evidence for recombination losses is observed for pressures up to 3,000 Torr.

  8. 17 CFR Appendix A to Subpart A of... - Appendix A to Subpart A of Part 248 Forms

    Science.gov (United States)

    2010-04-01

    ... in color. (e) Languages. The model form may be translated into languages other than English. C...; payment history; transaction history; transaction or loss history; credit history; credit scores; assets; investment experience; credit-based insurance scores; insurance claim history; medical information;...

  9. 24 CFR 203.43h - Eligibility of mortgages on Indian land insured pursuant to section 248 of the National Housing Act.

    Science.gov (United States)

    2010-04-01

    ... of the mortgagor; and (6) The Secretary had determined that no feasible financing alternative is... by the Secretary of the Interior, over which an Indian tribe is recognized by the United States as... held by any Indian tribe or individual subject to a restriction by the United States against...

  10. Insertion effects of various acid sensitive groups into acetal-type polymer on the profile of 248-nm chemically amplified resist

    Science.gov (United States)

    Chung, Yoon-Sik; Kim, Hyun-Jin; Cho, Sook H.; Lee, Dong H.; Im, Kwang H.; Yim, Yun-Gill; Kim, Deog-Bae; Kim, Jae-Hyun

    2002-07-01

    Various derivatives of modified poly(4-hydoxystyrene-co-4-(1-ethylethoxystyrene))(M-EEPHS) were synthesized by insertion of third monomer unit such as styrene, 4-acetoxystyrene, 4-methoxycarbonyloxystyrene, tertbutoxycarbonyloxystyrene, tert-butyl acrylate, and 4-(1-cyclohexylethoxy)styrene. Their dissolution rate behavior was investigated with different blocking level. From the average dissolution rate of M-EEPHS in a 2.38wt% TMAH solution as a function of the total protection%, hydrophobicity was proven as more influential factor for the dissolution inhibition rather than hydrogen bonding by ester or carbonate functionality in a blocking group. To study structural effect on KRF lithographic performance, resists containing M-EEPHS were formulated and testified. Defects that are found in EEPHS based resist, such as LER (Line Edge Roughness) and top surface erosion at defocus can be solved by incorporation of carbornate, bulky acetal functionality or dissolution inhibition group. When hybrid system, which contained both M-EEPHS and poly[4-hydroxystyrene-co-tert-butyl acrylate-co-4-(3-cyano-1,5-di-tert-butyl carbonyl pentyl styrene)](P(HS-TBA-CBPS)) as an annealing type resin, were compared with the lithographic results of single polymeric system (M-EEPHS only), their performances were directly projected to those of blends of high activation type and low activation type resin.

  11. Conflitos Sociais na Europa: uma paz impossível? 10.5102/uri.v4i1.248

    Directory of Open Access Journals (Sweden)

    Leila Bijos

    2007-08-01

    Full Text Available Análise dos movimentos sociais na França e na América Latina, num contexto de ausência de programas políticos de inserção de imigrantes. Por meio da violência, os jovens manifestantes expressam seu inconformismo com o desemprego, o fracasso escolar e outros sintomas da discriminação de que se julgam vítimas, inclusive por parte da polícia. A passagem do estado de natureza até o estado social produz no homem uma mudança bem acentuada, substituindo, em sua conduta, o instinto pelo sentimento de justiça, e outorgando a suas ações relações morais que antes estavam ausentes. À medida que a repressão se intensifique, fica ainda mais difícil a percepção da realidade. A França, como sociedade pode converter-se em uma ameaça a si própria ao não combinar integração e diferenças socioeconômicas, superando a oposição entre um modelo republicano e um comunitarismo carregado de agressividade. A América Latina vivenciou uma longa era de repressão militar, de violência, oprimida por um Estado distante dos indivíduos; incapaz de suprí-los com políticas públicas e sociais. Na sociedade civil é onde surgem e se desenvolvem os conflitos econômicos, sociais, ideológicos, religiosos, que as instituições públicas têm o dever de equacionar.

  12. Resenha: GOTTSCHALL, Jonathan. The story telling animal: how stories make us human. Boston,New York: Houghton Mifflin Harcourt, 2012. p. 248.

    Directory of Open Access Journals (Sweden)

    Marcus Assis Lima

    2014-04-01

    Full Text Available O autor é professor de Literatura Americana na Washington & Jefferson College, na Pensilvânia. Esse seu mais recente trabalho procura responder uma pergunta básica: Contar uma estória é apenas uma diversão e um passatempo ou tem alguma função biológica e, portanto, alguma função para espécie humana? Ele parte do princípio que "somos, como espécie, viciados em narrativas. Mesmo quando o corpo vai dormir, a mente continua alerta durante todo o sono, contando estórias a ela mesma" (p.xiv. Gottschall afirma que a mente humana não apenas foi "moldada para a ficção, mas que ela foi moldada pela ficção" (p.56. A "mente narrativa" é viciada em significados. Se ela não consegue encontrar um padrão de significados no mundo, ela irá tentar impor um padrão, ela é como uma fábrica que descarta muitas narrativas verdadeiras quando pode, mas que "também pode fabricar mentiras quando não encontra verdades" (p.103. Ele defende que uma estória de vida seria uma "mitologia pessoal" sobre quem somos - de onde viemos, como chegamos onde chegamos; são quem somos e formam nossa identidade. Em sua linha evolucionista de argumentos, Gottschall acredita que as narrativas, como os organismos biológicos, também evoluem, adaptando-se de acordo com demandas do ambiente. De modo que os seres humanos teriam evoluído para desejarem fortemente as narrativas e esse desejo tem sido um enorme benefício para todos nós: "As narrativas nos dão prazer e instruções. Elas simulam mundos de modo que possamos viver melhor no mundo reeal. Elas nos ajudam a criar laços comunais e a definir nossa cultura. As narrativas foram uma dádiva para nossa espécie" (p.197.

  13. A pacemaker with P = 2.48 h modulated the generator of flares in the X-ray light curve of Sgr A* in the year 2012

    Science.gov (United States)

    Leibowitz, Elia

    2017-01-01

    In an intensive observational campaign in the nine month duration of Chandra X-ray Visionary Project that was conducted in the year 2012, 39 large X-ray flares of Sgr A* were recorded. An analysis of the times of the observed flares reveals that the 39 flares are separated in time by intervals that are grouped around integer numbers times 0.10333 days. This time interval is thus the period of a uniform grid of equally spaced points on the time axis. The grouping of the flares around tic marks of this grid is derived from the data with at least a 3.2 σ level of statistical significance. No signal of any period can be found among 22 flares recorded by Chandra in the years 2013-2014. If the 0.10333 day period is that of a nearly circular Keplerian orbit around the blackhole at the center of the Galaxy, its radius is at 7.6 Schwarzschild radii. Large flares were more likely to be triggered when the agent responsible for their outbursts was near the peri-center phase of its slightly eccentric orbit.

  14. Donatella della Porta, Social Movements in Times of Austerity: Bringing Capitalism Back into Protest Analysis, Cambridge: Polity Press, 2015, 248 pages, ISBN-13: 9780745688589 (hbk

    Directory of Open Access Journals (Sweden)

    Marius Ioan TĂTAR

    2016-11-01

    Full Text Available The global economic crisis had major social and political impact on European societies. The political consequences of the crisis mainly stem from rising unemployment, the freezing or cuts of public sector pay, declining purchasing power, pessimism about future developments and perceptions of bad governance. In this context, a new wave of protest has spread across Europe as a reaction to the austerity measures adopted during the economic crisis. Governments’ inability to deal with the crisis has generated in many places anxiety, which then turned into popular anger. People who have been hard hit by the crisis placed most of the blame with incumbent governments and condemned the corruption and lack of political responsibility of the political class in general.

  15. A linkage map of cultivated cucumber (cucumis sativus l.) with 248 microsatellite marker loci and seven genes for horticulturally important traits

    Science.gov (United States)

    Marker assisted selection (MAS) is playing an increasingly important role in expedite and increase the efficiency of classical plant breeding. In cucumber, MAS is lagging behind as compared with other field crops. In the present study, a genetic map was developed with microsatellite (or simple seque...

  16. A Pacemaker with P=2.48 hour Modulated the Generator of Flares in the X-ray Light Curve of Sgr A* in the year 2012

    CERN Document Server

    Leibowitz, Elia M

    2016-01-01

    In an intensive observational campaign in the 9 month duration of Chandra X-ray Visionary Project that was conducted in the year 2012, 39 large X-ray flares of Sgr A* were recorded. An analysis of the times of the observed flares reveals that the 39 flares are separated in time by intervals that are grouped around integer numbers times 0.10333 days. This time interval is thus the period of a uniform grid of equally spaced points on the time axis. The grouping of the flares around tic marks of this grid is derived from the data with at least a 3.2 {\\sigma} level of statistical significance. No signal of any period can be found among 22 flares recorded by Chandra in the years 2013-2014. If the 0.10333 d period is that of a nearly circular Keplerian orbit around the blackhole at the center of the Galaxy, its radius is at 7.6 Schwarzschild radii. Large flares were more likely to be triggered when the agent responsible for their outbursts was near the peri-center phase of its slightly eccentric orbit.

  17. Observation on Clinical Therapeutic Effect of Magnetic Needle in Bell Paralysis%磁吸针治疗Bell麻痹248例疗效观察

    Institute of Scientific and Technical Information of China (English)

    钟建兵; 邓龙刚

    2010-01-01

    目的 探讨磁吸针治疗Bell麻痹的临床效果.方法 将444例Bell麻痹患者随机分成两组,治疗组采用磁吸针治疗,对照组采用针灸治疗.结果 治疗组治愈率(91.9%)、有效率(100.0%)高于对照组(70.9%、83.2%),两组比较差异有显著性意义(P<0.05).结论 磁吸针治疗Bell麻痹效果显著.

  18. Historic Archaeology of the Johnson (41DN248) and Jones (41DN250) Farmsteads in the Ray Roberts Lake Area: 1850-1950

    Science.gov (United States)

    1996-08-15

    92 7-5. Distribution of metal fragments in Block 1 ............................ 93 0 0 v *1 0 0 6 0S00 0 0 0 0 0 7-6. r:.-tograph of cast- iron ...elm, bois d’arc (Maclura pomifera) and mesquite ( Prosopis spp.) (Institute of Applied Sciences 1988:9-10; Yates and Ferring 1986:17). Along streams...accomplished using a carpenter’s tape. The height of the windmill had been changed by the addition of a new section of • angle iron , and numerous

  19. Collecting high-order interactions in an effective pairwise intermolecular potential using the hydrated ion concept: The hydration of Cf{sup 3+}

    Energy Technology Data Exchange (ETDEWEB)

    Galbis, Elsa; Pappalardo, Rafael R.; Marcos, Enrique Sánchez, E-mail: sanchez@us.es [Departmento de Química Física, Universidad de Sevilla, 41012 Seville (Spain); Hernández-Cobos, Jorge [Instituto de Ciencias Físicas, UNAM, Apartado Postal 48-3, 62251 Cuernavaca (Mexico)

    2014-06-07

    This work proposes a new methodology to build interaction potentials between a highly charged metal cation and water molecules. These potentials, which can be used in classical computer simulations, have been fitted to reproduce quantum mechanical interaction energies (MP2 and BP86) for a wide range of [M(H{sub 2}O){sub n}]{sup m+}(H{sub 2}O){sub ℓ} clusters (n going from 6 to 10 and ℓ from 0 to 18). A flexible and polarizable water shell model (Mobile Charge Density of Harmonic Oscillator) has been coupled to the cation-water potential. The simultaneous consideration of poly-hydrated clusters and the polarizability of the interacting particles allows the inclusion of the most important many-body effects in the new polarizable potential. Applications have been centered on the californium, Cf(III) the heaviest actinoid experimentally studied in solution. Two different strategies to select a set of about 2000 structures which are used for the potential building were checked. Monte Carlo simulations of Cf(III)+500 H{sub 2}O for three of the intermolecular potentials predict an aquaion structure with coordination number close to 8 and average R{sub Cf−−O} in the range 2.43–2.48 Å, whereas the fourth one is closer to 9 with R{sub Cf−−O} = 2.54 Å. Simulated EXAFS spectra derived from the structural Monte Carlo distribution compares fairly well with the available experimental spectrum for the simulations bearing 8 water molecules. An angular distribution similar to that of a square antiprism is found for the octa-coordination.

  20. 78 FR 21567 - Installation of Radiation Alarms for Rooms Housing Neutron Sources

    Science.gov (United States)

    2013-04-11

    ... californium-252 (Cf-252). A licensee's decision to use a specific type of source may depend upon cost, availability, and the dependence upon historical data with which to compare current measurement results. The...

  1. Coaching women to lead Averil Leimon Coaching women to lead , François Moscovici and Helen GoodierRoutledge £16.99 | 248pp 9780415491068 0415491061 [Formula: see text].

    Science.gov (United States)

    2011-05-01

    WOMEN'S LEADERSHIP is a relatively unusual and rare topic for a book, so I was delighted to be asked to review this. This is not a nursing book, but its relevance to nursing and the implications for nurse leadership are clear. nursing is a profession that is predominantly female and the obstacles women face are similar, whether they are from a nursing or a banking background.

  2. Design and characterization of a low-viscous muscle tissue mimicking media at the ISM-band (2.4–2.48 GHz) for easy antenna displacement in in vitro measurements

    DEFF Research Database (Denmark)

    Jónasson, Sævar Þór; Zhurbenko, Vitaliy; Johansen, Tom Keinicke

    2012-01-01

    Phantoms mimicking electromagnetic properties of biological tissues are widely used in evaluation of electromagnetic field distribution in human body. In this paper, low-viscous, optically transparent liquids that mimic muscle tissue, are designed and characterized. Various mixing ratios of de-io...... be produced. For example, a recipe for the grey matter of the human brain is suggested, resulting in less than 4.7% deviation. An improved recipe for muscle tissue, where Triton X-100 is added, improves the target recipe to less than 1% deviation from the reference....

  3. Resonant two-photon ionization of phenol in methylene chloride doped solid argon using 248 nm KrF laser and 254 nm Hg lamp radiation, a comparative study. The UV/VIS absorption spectrum of phenol radical cation

    Science.gov (United States)

    Kesper, Karl; Diehl, Frank; Simon, Jens Georg Günther; Specht, Harald; Schweig, Armin

    1991-06-01

    Resonant two-photon ionization (TPI) of phenol (PhOH) has been successfully achieved in methylene chloride (CH 2Cl 2) doped solid argon using a KrF laser and a Hg resonance lamp. The result constitutes the first-time TPI of a typically organic molecule in this medium using an excimer laser as well as the first-time spectroscopic identification of PhOH +•. A qualitative model is proposed which is consistent with both the unexpected photostability of PhOH +• and the incomplete running of the TPI process in the applied medium.

  4. CTD data of the Hawaii Ocean Time-series (HOT) program in the North Pacific 100 miles north of Oahu, Hawaii for cruises HOT239-248 during 2012 (NODC Accession 0119895)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The HOT program makes repeated observations of the physics, biology and chemistry at a site approximately 100 km north of Oahu, Hawaii. Two stations are visited...

  5. A new shipping container for an intense neutron emitter

    Energy Technology Data Exchange (ETDEWEB)

    Bigelow, J.E.; Alexander, C.W.; Pace, J.V. III; Simmons, C.M.

    1994-06-01

    Californium-252 is an intense neutron emitter (2.34 {times} 10{sup 12} n/s{center_dot}g) used in medicine, research, and industry. The western world`s sole source of this rare radioisotope is the Californium Facility at Oak Ridge National Laboratory`s Radiochemical Engineering Development Center (REDC). A project has been initiated at the REDC to design a new Type B Californium Shipping Container. This effort is essential for future transportation of californium to meet the needs of users all over the world. The shipping container must meet all requirements for transport by motor freight, air, vessel, and rail, both domestic and foreign. There are unique problems in the design, fabrication, and licensing of a new Type B shipping container that will accommodate up to 60 milligrams of californium-252. One of the first challenges in the design phase of the project is the selection of a material to shield the high neutron flux. The more stringent safety precautions of today`s world impel us to consider more exotic materials for such a purpose. The candidate materials must be examined not just for their neutron shielding properties, but also in conjunction with other properties such as thermal and structural requirements to withstand the hypothetical accident conditions. The design and building of such a container is a formidable task requiring much planning. The licensing process, with the complex, interactive federal codes, is a special challenge and may be the biggest on the project in terms of time and money.

  6. Dicty_cDB: Contig-U14796-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ||||||| Sbjct: 132 agatcaaatttaaaagtgacgaaccattaatttacatgggataattaaacaaatatcagt 191 Query: 192 agtgttggattggttatttgcttccacttttgctttca...bjct: 192 agtgttggattggttatttgcttccacttttgctttcanggagctcagatatatcac 248 Score = 3...taattaaacaaatatcagt 59 Query: 192 agtgttggattggttatttgcttccacttttgctttcanggagctcagatatatcac 248 ||||||||||||...||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 58 agtgttggattggttatttgcttccacttttgctttcanggagctcagatat

  7. Discovery of Isotopes of the Transuranium Elements with 93 <= Z <= 98

    CERN Document Server

    Fry, C

    2012-01-01

    One hundred and five isotopes of the transuranium elements neptunium, plutonium, americium, curium, berkelium and californium have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  8. 77 FR 75831 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2012-12-26

    ..., contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ, phone: 011-44..., Corporate Communications, P.O. Box 31, Derby, England, DE248BJ, phone: 011-44-1332-242424; fax:...

  9. 77 FR 58762 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2012-09-24

    ..., contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ, phone: 011-44..., Corporate Communications, P.O. Box 31, Derby, England, DE248BJ, phone: 011-44-1332-242424; fax:...

  10. 77 FR 31176 - Airworthiness Directives; Rolls-Royce plc (RR) Turbofan Engines

    Science.gov (United States)

    2012-05-25

    ... plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424; fax..., contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone:...

  11. 77 FR 13483 - Airworthiness Directives; Rolls-Royce plc (RR) Turbofan Engines

    Science.gov (United States)

    2012-03-07

    ... Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332..., contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone:...

  12. 77 FR 40820 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2012-07-11

    ...-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424..., contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, ] England, DE248BJ; phone:...

  13. 77 FR 6668 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2012-02-09

    ... plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424; fax..., Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424; fax:...

  14. « Islamic Restorative Traditions and Their Reflections in the Post Revolutionary Criminal Justice System of Iran ». European Journal of Crime, Criminal Law and Criminal Justice, Vol. 15, N° 2, 2007, pp. 227-248.

    OpenAIRE

    Engeland, Anicée Van

    2010-01-01

    L’A. s’interroge sur l’utilité sociale de punir et sur l’opportunité de « qui punir ». C’est ainsi qu’il approche le droit pénal iranien comme une réparation du criminel envers la société. Il se concentre alors sur la notion de violation du devoir moral. Le crime de qiṣāṣ (réparation pour un homicide ou pour une blessure) a selon lui cette approche du droit pénal : il s’agit de la violation d’un devoir moral et la réparation doit de ce fait être proportionnelle au mal qui a été fait à la soci...

  15. Study of Search Engine Transaction Logs Shows Little Change in How Users use Search Engines. A review of: Jansen, Bernard J., and Amanda Spink. “How Are We Searching the World Wide Web? A Comparison of Nine Search Engine Transaction Logs.” Information Processing & Management 42.1 (2006: 248‐263.

    Directory of Open Access Journals (Sweden)

    David Hook

    2006-09-01

    Full Text Available Objective – To examine the interactions between users and search engines, and how they have changed over time. Design – Comparative analysis of search engine transaction logs. Setting – Nine major analyses of search engine transaction logs. Subjects – Nine web search engine studies (4 European, 5 American over a seven‐year period, covering the search engines Excite, Fireball, AltaVista, BWIE and AllTheWeb. Methods – The results from individual studies are compared by year of study for percentages of single query sessions, one term queries, operator (and, or, not, etc. usage and single result page viewing. As well, the authors group the search queries into eleven different topical categories and compare how the breakdown has changed over time. Main Results – Based on the percentage of single query sessions, it does not appear that the complexity of interactions has changed significantly for either the U.S.‐based or the European‐based search engines. As well, there was little change observed in the percentage of one‐term queries over the years of study for either the U.S.‐based or the European‐based search engines. Few users (generally less than 20% use Boolean or other operators in their queries, and these percentages have remained relatively stable. One area of noticeable change is in the percentage of users viewing only one results page, which has increased over the years of study. Based on the studies of the U.S.‐based search engines, the topical categories of ‘People, Place or Things’ and ‘Commerce, Travel, Employment or Economy’ are becoming more popular, while the categories of ‘Sex and Pornography’ and ‘Entertainment or Recreation’ are declining. Conclusions – The percentage of users viewing only one results page increased during the years of the study, while the percentages of single query sessions, oneterm sessions and operator usage remained stable. The increase in single result page viewing implies that users are tending to view fewer results per web query. There was also a significant difference in the percentage of queries using Boolean operators between the US‐based and the European‐based search engines. One of the study’s findings was that results from a study of a particular search engine cannot necessarily be applied to all search engines. Finally, web search topics show a trend towards information or commerce searching rather than entertainment.

  16. International Electronic Journal of Elementary Educ ation, 2013, 5(3, 233-248. ISSN:1307 9298 Copyright © IEJEE www.iejee.com Relationship among Students’ Attitudes, Intentions and Behaviors towards the Inclusion of Peers with Disabilities, in Mainstream Physical Education Classes

    Directory of Open Access Journals (Sweden)

    Evangelos BEBETSOS

    2013-07-01

    Full Text Available Students’ attitudes, intentions and behaviours towards their peers with disabilities are important to their mutual co existence and development. The aim of this study was to investigate a whetherstudents’ attitudes and intentions towards their schoolmates with disabilities are related to their general and modified behavior in mainstream physical education classes, and b if the former variables could serve as predictors of the latter. The participants, 172 children without disabilities(Mage=11.15,SD=.70, completed the revised version of the Planned Behavior Theory questionnaire(PBT and the Children’s’ Attitudes towards Inclusion in Physical Education – Revised questionnaire(CAIPE R. Although results revealed several correlations among the variables under study, only general attitudes accounted for both general and modified behavior, and attitudes for modified behavior. These findings could assist in educating students to develop and perform appropriate behaviours towards their peers in order to facilitate their co existence, and their mutual developmentand learning.

  17. Corrigendum to "The 16 April 2016, MW 7.8 (MS 7.5) Ecuador earthquake: A quasi-repeat of the 1942 MS 7.5 earthquake and partial re-rupture of the 1906 MS 8.6 Colombia-Ecuador earthquake" [Earth Planet. Sci. Lett. 454 (2016) 248-258

    Science.gov (United States)

    Ye, Lingling; Kanamori, Hiroo; Avouac, Jean-Philippe; Li, Linyan; Cheung, Kwok Fai; Lay, Thorne

    2017-01-01

    In response to inquiries from readers of the paper, we have reexamined the time series recorded at DART 32067 and confirmed the existence of a data gap in the recording between 19 and 34 min after the earthquake initiation time. The recorded time series also includes short-period ground oscillations and long-period tidal fluctuations. We originally had run the records through a script that re-sampled the data to uniform intervals and filtered out the tidal signals. This inadvertently interpolated across the data gap and distorted the signal. We misinterpreted the interpolated feature as the second arrival of the recorded tsunami in the top panel of Figs. 3e, S3e, and S4e. The recorded waveform in the corrected version of Fig. 3e appended herein has instead been de-tided using the OTIS Regional Tidal Solutions (http://volkov.oce.orst.edu/tides/PO.html).

  18. Comment on "Nanosecond laser textured superhydrophobic metallic surfaces and their chemical sensing applications" by Duong V. Ta, Andrew Dunn, Thomas J. Wasley, Robert W. Kay, Jonathan Stringer, Patrick J. Smith, Colm Connaughton, Jonathan D. Shephard (Appl. Surf. Sci. 357 (2015) 248-254)

    Science.gov (United States)

    Boinovich, L. B.; Emelyanenko, A. M.; Emelyanenko, K. A.; Domantovsky, A. G.; Shiryaev, A. A.

    2016-08-01

    Nowadays the problem of design of durable ecologically friendly superhydrophobic surfaces is of great importance for science and technology. A recent paper in Applied Surface Science reports the method of fabricating the superhydrophobic metallic surfaces by infrared nanosecond laser surface texturing without using hydrophobic agents. Since this method of surface texturing can be considered as one of the most suitable for various industrial applications, the nature of superhydrophobic state of surfaces produced by laser texturing in the abovementioned paper deserves to be analyzed in detail. Authors of the commented paper attributed the change in wettability to the partial deoxidation of CuO into Cu2O on the surface during storage in atmosphere. However, such interpretation of the results contradicts to the basic notions in the theory of wetting and to more accurate and detailed data. In our Comment we discuss these contradictions point by point.

  19. Dicty_cDB: Contig-U13130-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available gatatattaatcaaggtaattntttaaatgatccaataaca 397 Query: 398 ttagantttggtgatgtttcaaccgattagaaataataccaaatc 442 |...|||||||||||||||||||||||||||||||||||||||||||| Sbjct: 398 ttagantttggtgatgtttcaaccg...tcaaggtaattntttaaatgatccaataacattagantttggtgatgtttcaaccg 422 |||||||||||||||||||||||||||||||||||||||||||||||...||||||||||||| Sbjct: 248 ttaatcaaggtaattntttaaatgatccaataacattagantttggtgatgtttca

  20. Measurement of the energy spectra of fission fragments using nuclear track detectors and digital image processing

    Energy Technology Data Exchange (ETDEWEB)

    Espinosa, Guillermo; Golzarri, Jose I. [Instituto de Fisica, Universidad Nacional Autonoma de Mexico, A.P. 20-364, Mexico D.F. 01000 (Mexico); Castano, Victor M., E-mail: castano@fata.unam.m [Centro de Fisica Aplicada y Tecnologia Avanzada, Universidad Nacional Autonoma de Mexico, Boulevard Juriquilla 3001, Santiago de Queretaro, Queretaro 76230 (Mexico)

    2010-08-15

    Energy spectra of fission fragments were determined using a Nuclear Track Methodology (NTM) supported by digital image analysis and numerical data processing using a standard personal computer. The analysis of a californium ({sup 252}Cf) spectrum with this approach shows improvement compared with the values reported previously using the standard procedure, in terms of resolution and accuracy. This new method adds full automation to the technical advantages and cost effectiveness of an NTM.

  1. TOWARD AN IMPROVED UNDERSTANDING OF STRUCTURE AND MAGNETISM IN NEPTUNIUM AND PLUTONIUM PHOSPHONATES AND SULFONATES

    Energy Technology Data Exchange (ETDEWEB)

    Albrecht-Schmitt, Thomas

    2012-03-01

    This grant supported the exploratory synthesis of new actinide materials with all of the actinides from thorium to californium with the exceptions of protactinium and berkelium. We developed detailed structure-property relationships that allowed for the identification of novel materials with selective ion-exchange, selective oxidation, and long-range magnetic ordering. We found novel bonding motifs and identified periodic trends across the actinide series. We identified structural building units that would lead to desired structural features and novel topologies. We also characterized many different spectroscopic trends across the actinide series. The grant support the preparation of approximately 1200 new compounds all of which were structurally characterized.

  2. Detection of rare earth elements in Powder River Basin sub-bituminous coal ash using laser-induced breakdown spectroscopy (LIBS)

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Phuoc [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State; Mcintyre, Dustin [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State

    2015-10-01

    We reported our preliminary results on the use of laser-induced breakdown spectroscopy to analyze the rare earth elements contained in ash samples from Powder River Basin sub-bituminous coal (PRB-coal). We have identified many elements in the lanthanide series (cerium, europium, holmium, lanthanum, lutetium, praseodymium, promethium, samarium, terbium, ytterbium) and some elements in the actinide series (actinium, thorium, uranium, plutonium, berkelium, californium) in the ash samples. In addition, various metals were also seen to present in the ash samples

  3. NONDESTRUCTIVE IDENTIFICATION OF CHEMICAL WARFARE AGENTS AND EXPLOSIVES BY NEUTRON GENERATOR-DRIVEN PGNAA

    Energy Technology Data Exchange (ETDEWEB)

    T. R. Twomey; A. J. Caffrey; D. L. Chichester

    2007-02-01

    Prompt gamma-ray neutron activation analysis (PGNAA) is now a proven method for the identification of chemical warfare agents and explosives in military projectiles and storage containers. Idaho National Laboratory is developing a next-generation PGNAA instrument based on the new Ortec Detective mechanically-cooled HPGe detector and a neutron generator. In this paper we review PGNAA analysis of suspect chemical warfare munitions, and we discuss the advantages and disadvantages of replacing the californium-252 radioisotopic neutron source with a compact accelerator neutron generator.

  4. An ECR Charge Breeder for the 252 Cf Fission Source Project (CARIBU) at ATLAS%ATLAS用于CARIBU项目的ECR离子剥离器

    Institute of Scientific and Technical Information of China (English)

    R.C.Pardo; R.Vondrasek; T.Kulevoy; V.Aseev; R.Scott; P.Suominen

    2007-01-01

    A new radioactive beam facility for ATLAS,the Californium Rare Ion Breeder Upgrade(CARIBU),is under construction.The facility will use fission fragments from a 1 Ci 252 Cf source;thermalized and collected into a low-energy beam by a helium gas catcher.In order to reaccelerate these beams.the existing ATLAS ECR-I ion source is being redesigned to function as a charge breeder source.The design and features of this charge breeder configuration is discussed and the project status described.

  5. Advanced development of the spectrum sciences Model 5005-TF, single-event test fixture

    Energy Technology Data Exchange (ETDEWEB)

    Ackermann, M.R.; Browning, J.S. (Sandia National Labs., Albuquerque, NM (USA)); Hughlock, B.W. (Boeing Aerospace and Electronics Co., Seattle, WA (USA)); Lum, G.K. (Lockheed Missiles and Space Co., Sunnyvale, CA (USA)); Tsacoyeanes, W.C. (Draper (Charles Stark) Lab., Inc., Cambridge, MA (USA)); Weeks, M.D. (Spectrum Sciences, Inc., Santa Clara, CA (USA))

    1990-09-01

    This report summarizes the advanced development of the Spectrum Sciences Model 5005-TF, Single-Event Test Fixture. The Model 5005-TF uses a Californium-252 (Cf-252) fission-fragment source to test integrated circuits and other devices for the effects of single-event phenomena. Particle identification methods commonly used in high-energy physics research and nuclear engineering have been incorporated into the Model 5005-TF for estimating the particle charge, mass, and energy parameters. All single-event phenomena observed in a device under test (DUT) are correlated with an identified fission fragment, and its linear energy transfer (LET) and range in the semiconductor material of the DUT.

  6. Method for measuring multiple scattering corrections between liquid scintillators

    Science.gov (United States)

    Verbeke, J. M.; Glenn, A. M.; Keefer, G. J.; Wurtz, R. E.

    2016-07-01

    A time-of-flight method is proposed to experimentally quantify the fractions of neutrons scattering between scintillators. An array of scintillators is characterized in terms of crosstalk with this method by measuring a californium source, for different neutron energy thresholds. The spectral information recorded by the scintillators can be used to estimate the fractions of neutrons multiple scattering. With the help of a correction to Feynman's point model theory to account for multiple scattering, these fractions can in turn improve the mass reconstruction of fissile materials under investigation.

  7. PROCEEDINGS OF THE SYMPOSIUM COMMEMORATING THE 25th ANNIVERSARY OF ELEMENTS 97 and 98 HELD ON JAN. 20, 1975

    Energy Technology Data Exchange (ETDEWEB)

    Seaborg, Glenn T.; Street Jr., Kenneth; Thompson, Stanley G.; Ghiorso, Albert

    1976-07-01

    This volume includes the talks given on January 20, 1975, at a symposium in Berkeley on the occasion of the celebration of the 25th anniversary of the discovery of berkelium and californium. Talks were given at this symposium by the four people involved in the discovery of these elements and by a number of people who have made significant contributions in the intervening years to the investigation of their nuclear and chemical properties. The papers are being published here, without editing, in the form in which they were submitted by the authors in the months following the anniversary symposium, and they reflect rather faithfully the remarks made on that occasion.

  8. 78 FR 64242 - Outer Continental Shelf (OCS), Gulf of Mexico (GOM), Oil and Gas Lease Sales, Western Planning...

    Science.gov (United States)

    2013-10-28

    ... Bureau of Ocean Energy Management Outer Continental Shelf (OCS), Gulf of Mexico (GOM), Oil and Gas Lease Sales, Western Planning Area (WPA) Lease Sales 238, 246, and 248 AGENCY: Bureau of Ocean Energy... proposed OCS oil and gas Lease Sales 238, 246, and 248, which are tentatively scheduled to be held...

  9. Gclust Server: 201207 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 201207 TET_248.m00028 Cluster Sequences - 203 hypothetical protein chr_0_8253855_24...8; no annotation 1 1.00e-80 0.0 11.11 0.0 0.0 0.0 0.0 Show 201207 Cluster ID 201207 Sequence ID TET_248.m000

  10. Drug: D05945 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available rial; Coccidiostat [for poultry] CAS: 127-77-5 PubChem: 47207603 LigandBox: D05945 NIKKAJI: J5.401A ATOM 17 ...D05945 Drug Sulfabenz (USAN/INN) C12H12N2O2S 248.0619 248.3009 D05945.gif Antibacte

  11. AcEST: DK960998 [AcEST

    Lifescience Database Archive (English)

    Full Text Available S=Medic... 248 2e-64 tr|B5LWQ7|B5LWQ7_ZIZJJ Ubiquitin extensive-like protein OS=Zizip... 248 2e-64 tr|A9RJI9...RHYCGKCGLTYVYQKA Sbjct: 121 CPNAECGAGTFMANHFDRHYCGKCGLTYVYQKA 153 >tr|B5LWQ7|B5LWQ7_ZIZJJ Ubiquitin extensive

  12. AcEST: DK960484 [AcEST

    Lifescience Database Archive (English)

    Full Text Available rized protein OS=Medic... 248 2e-64 tr|B5LWQ7|B5LWQ7_ZIZJJ Ubiquitin extensive-like protein OS=Zizip... 248 ...N ECGAGTFMANH DRHYCGKCGLTYVYQKA Sbjct: 121 CPNAECGAGTFMANHFDRHYCGKCGLTYVYQKA 153 >tr|B5LWQ7|B5LWQ7_ZIZJJ Ubiquitin extensive

  13. 77 FR 13449 - Identity Theft Red Flags Rules

    Science.gov (United States)

    2012-03-06

    ... Commission 17 CFR Part 248 Identity Theft Red Flags Rules; Proposed Rule #0;#0;Federal Register / Vol. 77... Part 162 RIN 3038-AD14 SECURITIES AND EXCHANGE COMMISSION 17 CFR Part 248 RIN 3235-AL26 Identity Theft... that are subject to the Commissions' jurisdiction to address identity theft in two ways. First,...

  14. Drug: D02904 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D02904 Drug Amiloxate (USP/INN); Neo Heliopan (TN) C15H20O3 248.1412 248.3175 D02904.gif Sunscreen [ultravio...let B absorber] CAS: 71617-10-2 PubChem: 17397061 LigandBox: D02904 NIKKAJI: J298.9

  15. Drug: D09018 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D09018 Drug Tilarginine acetate (USAN) C7H16N4O2. C2H4O2 248.1485 248.2795 D09018.gif Treatment of cardiogen...ic shock complicating acute myocardial infarction [MI] non-selective nitric oxide s

  16. Dicty_cDB: SHB225 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available J132370 |pid:none) Allogromia sp. mRNA for actin 1. 254 6e-66 AY452189_1( AY452189 |pid:none) Sorosphaera veronica...e actin 1 gene... 248 4e-64 AY452190_1( AY452190 |pid:none) Sorosphaera veronicae actin 2 gene... 248

  17. High-Temperature Ferromagnetism in Cr- and Mn-Implanted Al(sub x)Ga(sub 1-x)N

    Science.gov (United States)

    2007-09-23

    Uspenskii , E. Kulatov, H. Mariette, H. Nakayama, H. Ohta, J. Magnetism and Magnetic Mat. 258-259, 248 (2003). [4] T. Dietl, Semicon. Science and Tech...287 (2000) 1019–1022. [3] Y. Uspenskii , E. Kulatov, H. Mariette, H. Nakayama, H. Ohta, J. Magn. Magn. Mater. 258–259 (2003) 248–250. [4] T. Dietl

  18. Dicty_cDB: Contig-U10615-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Expect = 2e-66 Identities = 248/248 (100%) Strand = Plus / Plus Query: 11 acaaccanaaaanatttccgnatcatcacatgnatgganatcnccna...anaaaanatttccgnatcatcacatgnatgganatcnccnaatgnattcaattc 70 Query: 71 atcntttgggatccntntganattacnccna...|||| Sbjct: 71 atcntttgggatccntntganattacnccnacntccnctggngnanantcaatcccttta 130 Query: 131 ncaaaaccnnangctgg...212 (95%) Strand = Plus / Plus Query: 12 caaccanaaaanatttccgnatcatcacatgnatgganatcnccnaatgnattcaattca 71 |||...||||||||||||||||||||||| || ||||||||||||||||| |||||||||||| Sbjct: 11 caaccanaaaanatttccgnatcatcncangnatgganatcnccna

  19. En frygtindgydende munterhed

    DEFF Research Database (Denmark)

    Haarder, Jon Helt

    2008-01-01

    Imre Kertész: DOSSIER K. (K. dosszié). Oversat fra ungarsk. af Peter Eszerhás. 224 sider, 248 kr. Batzer og co. Er udkommet. Fem stjerner.......Imre Kertész: DOSSIER K. (K. dosszié). Oversat fra ungarsk. af Peter Eszerhás. 224 sider, 248 kr. Batzer og co. Er udkommet. Fem stjerner....

  20. 77 FR 32007 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2012-05-31

    ... plc, Corporate Communications, P.O. Box 31, Derby, England DE248BJ; phone: 011-44-1332-242424; fax...-Royce plc, Corporate Communications, P.O. Box 31, Derby, England DE248BJ; phone: 011-44-1332-242424;...

  1. 78 FR 60658 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2013-10-02

    ..., contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44.... (ii) None. (3) For service information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424; fax: 011-44-1332- 249936;...

  2. 78 FR 6206 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2013-01-30

    ..., Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424; fax: 011-44-1332... this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ;...

  3. Improved charge breeding efficiency of light ions with an electron cyclotron resonance ion source

    Energy Technology Data Exchange (ETDEWEB)

    Vondrasek, R.; Kutsaev, Sergey [Argonne National Laboratory, Argonne, Illinois 60439 (United States); Delahaye, P.; Maunoury, L. [Grand Accelerateur National d' Ions Lourds (GANIL), CEA/DSM-CNRS/IN2P3, Blvd Henri Becquerel, 14076 Caen (France)

    2012-11-15

    The Californium Rare Isotope Breeder Upgrade is a new radioactive beam facility for the Argonne Tandem Linac Accelerator System (ATLAS). The facility utilizes a {sup 252}Cf fission source coupled with an electron cyclotron resonance ion source to provide radioactive beam species for the ATLAS experimental program. The californium fission fragment distribution provides nuclei in the mid-mass range which are difficult to extract from production targets using the isotope separation on line technique and are not well populated by low-energy fission of uranium. To date the charge breeding program has focused on optimizing these mid-mass beams, achieving high charge breeding efficiencies of both gaseous and solid species including 14.7% for the radioactive species {sup 143}Ba{sup 27+}. In an effort to better understand the charge breeding mechanism, we have recently focused on the low-mass species sodium and potassium which up to present have been difficult to charge breed efficiently. Unprecedented charge breeding efficiencies of 10.1% for {sup 23}Na{sup 7+} and 17.9% for {sup 39}K{sup 10+} were obtained injecting stable Na{sup +} and K{sup +} beams from a surface ionization source.

  4. Level structures of neutron-rich Xe isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Ahmad, I.; Lister, C.J.; Morss, L.R. [and others

    1995-08-01

    The level structures of neutron-rich Xe isotopes were determined by observing prompt gamma-ray coincidences in {sup 248}Cm fission fragments. A 5-mg {sup 248}Cm, in the form of {sup 248}Cm-KCl pellet, was placed inside Eurogam array which consisted of 45 Compton-suppressed Ge detectors and 5 Low-Energy Photon Spectrometers. Transitions in Xe isotopes were identified by the appearance of new peaks in the {gamma}-ray spectra obtained by gating on the gamma peaks of the complementary Mo fragments.

  5. Novel Molecular Imaging Agents to Detect Biomarkers of Metastatic Breast Cancer

    Science.gov (United States)

    2006-01-01

    19) Tsujimoto, T.; Murai A.; Synlett , 2002, 8, 1283-1284. (20) Gisin, B. Anal. Chim. Acta, 1972, 58, 248-249. (21) Fields, C. G.; Lloyd, D. H...New York, 1992, 77-183. (4) Tsujimoto, T.; Murai A.; Synlett , 2002, 8, 1283-1284. (5) Gisin, B. Anal. Chim. Acta, 1972, 58, 248-249 (6) Fields, C...T.; Murai A.; Synlett , 2002, 8, 1283-1284. (5) Gisin, B. Anal. Chim. Acta, 1972, 58, 248-249. (6) Fields, C. G.; Lloyd, D. H.; Macdonald, R. L.; Otteson, K. M.; Noble, R. L. Peptide Res., 1991, 4, 95-101.

  6. Post surgical pain treatment - adults

    Science.gov (United States)

    ... of Anesthesiologists Task Force on Acute Pain Management. Anesthesiology . 2012;116:248-73. PMID: 22227789 www.ncbi. ... chap 18. Sherwood ER, Williams CG, Prough DS. Anesthesiology principles, pain management, and conscious sedation. In: Townsend ...

  7. Drug: D09741 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available mones 248 Mixed hormone preparations 2482 Estrogens and progestins D09741 Drospiren...[HSA:1557] Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 24 Hor

  8. 75 FR 6872 - Aransas National Wildlife Refuge Complex, Aransas, Calhoun, and Refugio Counties, TX

    Science.gov (United States)

    2010-02-12

    ... documents by any of the following methods: E-mail: Roxanne_Turley@fws.gov . Include ``Aransas CCP'' in the subject line of the message. Fax: Attn: Roxanne Turley, 505-248-6874. U.S. Mail: Roxanne Turley,...

  9. Light-Propagation Characteristics of Photonic Crystal Waveguide Based on SOI Materials at Different Polarized States

    Institute of Scientific and Technical Information of China (English)

    WANG Chun-Xia; XU Xing-Sheng; LI Fang; DU Wei; XIONG Gui-Guang; LIU Yu-Liang; CHEN Hong-Da

    2006-01-01

    @@ Strgight single-line defect optical waveguides in photonic crystal slabs are designed by the plane wave expansion method and fabricated into silicon-on-insulator (SOI) wafer by 248-nm deep UV lithography.

  10. QTL Information Table: 229 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available ). Characterization of the main effects, epistatic effects and their environmental interactions of QTLs on the genetic basis of yield traits in rice. Theor Appl Genet 105, 248-257. ...

  11. Drug: D00592 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 248.3009 D00592.gif Antibacterial [leprostatic]; Suppressant [dermatitis herpetiformis] [DS:H00344] Same as... 62 Chemotherapeutics 623 Leprostatics 6231 Sulfones D00592 Diaphenylsulfone (JAN); Dapsone (USP) Anatomical

  12. Osteonecrosis

    Science.gov (United States)

    ... or intravenous steroids Excessive alcohol use Sickle cell disease Radiation therapy Gaucher disease Decompression sickness from a lot of deep sea ... 2016:chap 248. Read More Broken bone Dislocation Gaucher disease Hip joint replacement Knee joint replacement Radiation therapy ...

  13. Serological evidence of exposure to globally relevant zoonotic parasites in the Estonian population

    DEFF Research Database (Denmark)

    Lassen, Brian; Janson, Marilin; Viltrop, Arvo

    2016-01-01

    We investigated Estonian population and its selected subgroups for serological evidence of exposure to Ascaris lumbricoides, Echinococcus spp., Taenia solium, Toxocara canis, Toxoplasma gondii, and Trichinella spiralis. Serum samples from 999 adults representing general population, 248 children...

  14. Review: Lorenzo Cotula, The Great African Land Grab?: Agricultural Investments and the Global Food System (2013

    Directory of Open Access Journals (Sweden)

    Kerstin Nolte

    2013-01-01

    Full Text Available Review of the monograph:Lorenzo Cotula, The Great African Land Grab?: Agricultural Investments and the Global Food System, London, New York: Zed Books, 2013, ISBN 9781780324203, 248 pages

  15. 77 FR 2932 - Airworthiness Directives; Rolls-Royce plc (RR) Turbofan Engines

    Science.gov (United States)

    2012-01-20

    ...-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424... in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England,...

  16. 78 FR 54149 - Airworthiness Directives; Rolls-Royce plc (RR) Turbofan Engines

    Science.gov (United States)

    2013-09-03

    ... service information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31..., Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424; fax:...

  17. 78 FR 5126 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2013-01-24

    ... identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, DE248BJ, United... information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31,...

  18. 78 FR 11976 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2013-02-21

    ... information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby... Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone:...

  19. 78 FR 17297 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2013-03-21

    ... information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby..., contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone:...

  20. 76 FR 24796 - Airworthiness Directives; Rolls-Royce plc RB211-Trent 800 Series Turbofan Engines

    Science.gov (United States)

    2011-05-03

    ..., Corporate Communications, P.O. Box 31, Derby, England, DE248BJ, telephone: 011-44-1332-242424; fax: 011-44... 25, 2009 for related information. Contact Rolls-Royce plc, Corporate Communications, P.O. Box...

  1. 78 FR 17300 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2013-03-21

    ..., Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011 44 1332 242424; fax: 011 44 1332... service information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box...

  2. 77 FR 20508 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2012-04-05

    ..., contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ, telephone: 011-44... this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England,...

  3. 78 FR 28161 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2013-05-14

    .... For service information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O..., Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424; fax:...

  4. Genome Sequence of Mycobacterium Phage Waterfoul

    Science.gov (United States)

    Jackson, Paige N.; Embry, Ella K.; Johnson, Christa O.; Watson, Tiara L.; Weast, Sayre K.; DeGraw, Caroline J.; Douglas, Jessica R.; Sellers, J. Michael; D’Angelo, William A.

    2016-01-01

    Waterfoul is a newly isolated temperate siphovirus of Mycobacterium smegmatis mc2155. It was identified as a member of the K5 cluster of Mycobacterium phages and has a 61,248-bp genome with 95 predicted genes. PMID:27856585

  5. A Kind of Detecting and Control System of Temperatures%多路温度测控系统

    Institute of Scientific and Technical Information of China (English)

    池敏捷; 杨学友; 李晓峰

    2005-01-01

    文中介绍用PIC18F248单片机实现的多路温度实时检测控制系统,系统充分利用PIC18F248各种内部资源,使得整个系统的软硬件设计相对简化,易于实现,应用领域广泛.

  6. 黑白双色 飞利浦发布MODA系列显示器

    Institute of Scientific and Technical Information of China (English)

    冯华

    2011-01-01

    近日飞利浦发布了两款被命名为MODA摩登的显示器新品248C3L、248C3LH,无论从外观设计、制造工艺、色彩表现,还是应用体验上,都被誉为"飞利浦史上最美显示器"。

  7. EST Table: FS910504 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS910504 E_FL_fufe_20G20_F_0 11/12/09 n.h 10/09/28 39 %/248 aa ref|XP_967337.1| PREDICTED: similar to Serge.../244 aa gnl|Amel|GB17309-PA 10/09/10 39 %/248 aa gi|91083383|ref|XP_967337.1| PREDICTED: similar to Sergef protein [Tribolium castaneum] FS910504 fufe ...

  8. The logair Route Structure: An Exploration of the Single-Hub Concept.

    Science.gov (United States)

    1980-06-09

    available metho - dologies; for example, via linear programming, as was done by Foster and Ryan (15:248), Balinski and Quandt (15:248), and the thesis...scope of this project to argue the physical and technical feasibility of constructing a terminal with materiels handling equipment sufficient to...Gorychka, USAF. "A Mathematical Model for Determining LOGAIR Flight Schedules." Unpublished master’s thesis, SLSR 27-76A, Air Force Institute of

  9. Hospital Security and Force Protection: A Guide to Ensuring Patient and Employee Safety

    Science.gov (United States)

    2006-04-28

    removed from the mother baby unit. This technology also may be attached to equipment, decreasing theft of wheelchairs and other easily lost items (Noble... Pediatric Emergency Care, 19(4), 248-251. Hospital Security 93 State of Delaware. (2005). The history of terrorism: More than 200 years of development... Pediatric Emergency Care, 19(4), 248-251. Sullivan, M., & Donnelly, B. (2005). Emergency department response to terrorism. Topics in Emergency Medicine, 27

  10. Triton and alpha-particle contribution from LiF converter for neutron dosimeter

    CERN Document Server

    Camacho, M E; Balcazar, M

    1999-01-01

    A personnel neutron dosimeter prototype based on chemical and electrochemical etched CR-39 detector, combined with LiF converter, has been calibrated using an ICRP-like phantom, under a heavy-water moderated Californium source neutron spectra; A conversion factor of 1.052+-126 spots cm sup - sup 2 mSv sup - sup 1 was obtained. The sealing properties of the detector holder showed a ten-fold reduction in radon background when it was tested in a high radon atmosphere. A convenient mechanical shock resistance was achieved in LiF converters by sintering to 11 tons pressure LiF powder at 650 deg. C, during one hour.

  11. Reliability of semiconductor and gas-filled diodes for over-voltage protection exposed to ionizing radiation

    Directory of Open Access Journals (Sweden)

    Stanković Koviljka

    2009-01-01

    Full Text Available The wide-spread use of semiconductor and gas-filled diodes for non-linear over-voltage protection results in a variety of possible working conditions. It is therefore essential to have a thorough insight into their reliability in exploitation environments which imply exposure to ionizing radiation. The aim of this paper is to investigate the influence of irradiation on over-voltage diode characteristics by exposing the diodes to californium-252 combined neutron/gamma radiation field. The irradiation of semiconductor over-voltage diodes causes severe degradation of their protection characteristics. On the other hand, gas-filled over-voltage diodes exhibit a temporal improvement of performance. The results are presented with the accompanying theoretical interpretations of the observed changes in over-voltage diode behaviour, based on the interaction of radiation with materials constituting the diodes.

  12. First results from the CARIBU facility: mass measurements on the r-process path.

    Science.gov (United States)

    Van Schelt, J; Lascar, D; Savard, G; Clark, J A; Bertone, P F; Caldwell, S; Chaudhuri, A; Levand, A F; Li, G; Morgan, G E; Orford, R; Segel, R E; Sharma, K S; Sternberg, M G

    2013-08-09

    The Canadian Penning Trap mass spectrometer has made mass measurements of 33 neutron-rich nuclides provided by the new Californium Rare Isotope Breeder Upgrade facility at Argonne National Laboratory. The studied region includes the 132Sn double shell closure and ranges in Z from In to Cs, with Sn isotopes measured out to A=135, and the typical measurement precision is at the 100 ppb level or better. The region encompasses a possible major waiting point of the astrophysical r process, and the impact of the masses on the r process is shown through a series of simulations. These first-ever simulations with direct mass information on this waiting point show significant increases in waiting time at Sn and Sb in comparison with commonly used mass models, demonstrating the inadequacy of existing models for accurate r-process calculations.

  13. Nuclear fission and the transuranium elements

    Energy Technology Data Exchange (ETDEWEB)

    Seaborg, G.T.

    1989-02-01

    Many of the transuranium elements are produced and isolated in large quantities through the use of neutrons furnished by nuclear fission reactions: plutonium (atomic number 94) in ton quantities; neptunium (93), americium (95), and curium (96) in kilogram quantities; berkelium (97) in 100 milligram quantities; californium (98) in gram quantities; and einsteinium (99) in milligram quantities. Transuranium isotopes have found many practical applications---as nuclear fuel for the large-scale generation of electricity, as compact, long-lived power sources for use in space exploration, as means for diagnosis and treatment in the medical area, and as tools in numerous industrial processes. Of particular interest is the unusual chemistry and impact of these heaviest elements on the periodic table. This account will feature these aspects. 9 refs., 5 figs.

  14. Production of highly pure einsteinium and fermium preparations

    Energy Technology Data Exchange (ETDEWEB)

    Andreev, O.I.; Tarasov, V.A.; Zotov, E.A.; Baranov, A.Yu. [Federal State Unitary Enterprise ' ' State Scientific Center of Russian Federation Research Institute of Atomic Reactors' ' (Russian Federation)

    2004-07-01

    Highly pure einsteinium and fermium preparations are in increased demand due to the progress of the following fields of modern sciences: Fundamental and applied nuclear physics. Heavy actinides are necessary for detailed study of structure and decay of a nucleus, as well as initial material both for nuclear synthesis of new superheavy elements and for manufacturing radioactive radiation sources. Fundamental and applied radiochemistry. Einsteinium and fermium preparations are required to investigate chemical properties of these hard-to-obtain elements and to improve technology of their recovery and purification. Nuclear medicine. Biologically active compounds labeled with alpha- emitting einsteinium and fermium may be applied in prospect for a radioimmunotherapy of oncological diseases. The principal method of einsteinium and fermium production is irradiation of curium or californium isotopes in a high-flux nuclear reactor. Large-scale production of transplutonium elements at RIAR enables also to produce regularly significant quantities of einsteinium and fermium. (orig.)

  15. Beta-delayed neutron spectroscopy using ion traps

    Science.gov (United States)

    Wang, Barbara; Czeszumska, A.; Siegl, K.; Caldwell, S.; Aprahamian, A.; Burkey, M.; Clark, J.; Levand, A.; Marley, S.; Morgan, G.; Norman, E.; Nystrom, A.; Orford, R.; Padgett, S.; Perez Galvan, A.; Savard, G.; Scielzo, N.; Sharma, K.; Strauss, S.

    2017-01-01

    Trapped radioactive ions suspended in vacuum allow for a new way to perform beta-delayed neutron spectroscopy. Decay branching ratios and energy spectra of the emitted neutrons are inferred from a measurement of the nuclear recoil, thereby circumventing the many limitations associated with direct neutron detection. Beta-delayed neutron measurements were carried out for 137-138,140I, 134-136Sb, and 144-145Cs at the Californium Rare Isotope Breeder Upgrade (CARIBU) facility at Argonne National Laboratory. The data collected are needed in many fields of basic and applied science such as nuclear energy, nuclear astrophysics, and stockpile stewardship. Results for the isotopes 135-136Sb and 140I will be presented. Supported by NSF under PHY-1419765, and U.S. DOE under NEUP 13-5485, DE-AC02-06CH11357 (ANL), DE-AC52-07NA27344 (LLNL), and DE-NA0000979 (NNSA).

  16. Environmental assessment of the thermal neutron activation explosive detection system for concourse use at US airports

    Energy Technology Data Exchange (ETDEWEB)

    Jones, C.G.

    1990-08-01

    This document is an environmental assessment of a system designed to detect the presence of explosives in checked airline baggage or cargo. The system is meant to be installed at the concourse or lobby ticketing areas of US commercial airports and uses a sealed radioactive source of californium-252 to irradiate baggage items. The major impact of the use of this system arises from direct exposure of the public to scattered or leakage radiation from the source and to induced radioactivity in baggage items. Under normal operation and the most likely accident scenarios, the environmental impacts that would be created by the proposed licensing action would not be significant. 44 refs., 19 figs., 18 tabs.

  17. TRIGA-TRAP: A penning trap mass spectrometer at the research reactor TRIGA Mainz

    Energy Technology Data Exchange (ETDEWEB)

    Smorra, Christian [Physikalisches Institut, Universitaet Heidelberg (Germany); Institut fuer Kernchemie, Universitaet Mainz (Germany); Blaum, Klaus [Physikalisches Institut, Universitaet Heidelberg (Germany); Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Block, Michael; Herfurth, Frank [GSI, Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Eberhardt, Klaus [Institut fuer Kernchemie, Universitaet Mainz (Germany); Eibach, Martin; Ketelaer, Jens; Ketter, Jochen; Knuth, Konstantin; Repp, Julia [Institut fuer Physik, Universitaet Mainz (Germany); Nagy, Szilard [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany)

    2009-07-01

    Nuclear masses represent the binding energies and, therefore, the sum of all interactions in the nucleus. They provide an important input parameter to nuclear structure models. Presently, a tremendous interest in masses of very exotic neutron-rich nuclides exists to support theoretical models for the nucleosynthesis via the rapid neutron capture process. The research reactor TRIGA Mainz provides access to a large variety of neutron-rich nuclides produced by thermal-neutron induced fission of an actinide target. The double-Penning trap mass spectrometer TRIGA-TRAP will perform high-precision mass measurements in this region of the nuclear chart as well as on actinides from uranium to californium. It also serves as a test facility for the development of new techniques that will be implemented in future facilities like MATS at FAIR (GSI, Darmstadt). The layout of TRIGA-TRAP as well as recent mass measurements are presented.

  18. Populations of selected microbial and fungal species growing on the surface of rape seeds following treatment with desiccants or plant growth regulators.

    Science.gov (United States)

    Frac, Magdalena; Jezierska-Tys, Stefania; Tys, Jerzy

    2010-01-01

    The aim of this study was to determine the effects of desiccants and plant growth regulators on selected microbial species affecting rape seeds, with special emphasis on the growth of fungi and identification of the genus and species composition. The experimental material in the study was seeds of winter rape cv. Californium that were collected from the field during combine harvest. The chemical agents applied, both desiccants and growth regulators, generally decreased the populations of bacteria occurring on the surface of rape seeds. The responses of fungi depended upon the type of agent applied and were manifested as either stimulation or inhibition of the growth of the fungal species. The fungi isolated from the surface of rape seeds were characteristic of those found in the field environment (Cladosporium and Penicillium) and typical for those present on the surface of rape seeds (Alternaria).

  19. Measurements of the neutron capture cross sections and incineration potentials of minor-actinides in high thermal neutron fluxes: Impact on the transmutation of nuclear wastes; Mesures des sections efficaces de capture et potentiels d'incineration des actinides mineurs dans les hauts flux de neutrons: Impact sur la transmutation des dechets

    Energy Technology Data Exchange (ETDEWEB)

    Bringer, O

    2007-10-15

    This thesis comes within the framework of minor-actinide nuclear transmutation studies. First of all, we have evaluated the impact of minor actinide nuclear data uncertainties within the cases of {sup 241}Am and {sup 237}Np incineration in three different reactor spectra: EFR (fast), GT-MHR (epithermal) and HI-HWR (thermal). The nuclear parameters which give the highest uncertainties were thus highlighted. As a result of fact, we have tried to reduce data uncertainties, in the thermal energy region, for one part of them through experimental campaigns in the moderated high intensity neutron fluxes of ILL reactor (Grenoble). These measurements were focused onto the incineration and transmutation of the americium-241, the curium-244 and the californium-249 isotopes. Finally, the values of 12 different cross sections and the {sup 241}Am isomeric branching ratio were precisely measured at thermal energy point. (author)

  20. Mutant p53 promotes ovarian cancer cell adhesion to mesothelial cells via integrin β4 and Akt signals.

    Science.gov (United States)

    Lee, Jong-Gyu; Ahn, Ji-Hye; Jin Kim, Tae; Ho Lee, Jae; Choi, Jung-Hye

    2015-07-30

    Missense mutations in the TP53 gene resulting in the accumulation of mutant proteins are extremely common in advanced ovarian cancer, which is characterised by peritoneal metastasis. Attachment of cancer cells to the peritoneal mesothelium is regarded as an initial, key step for the metastatic spread of ovarian cancer. In the present study, we investigated the possible role of a p53 mutant in the mesothelial adhesion of ovarian cancer cells. We found that OVCAR-3 cells with the R248 TP53 mutation (p53(R248)) were more adhesive to mesothelial Met5A cells than were A2780 cells expressing wild-type p53. In addition, ectopic expression of p53(R248) in p53-null SKOV-3 cells significantly increased adhesion to Met5A cells. Knockdown of mutant p53 significantly compromised p53(R248)-induced cell adhesion to Met5A cells. Microarray analysis revealed that several adhesion-related genes, including integrin β4, were markedly up-regulated, and certain signalling pathways, including PI3K/Akt, were activated in p53(R248) transfectants of SKOV-3 cells. Inhibition of integrin β4 and Akt signalling using blocking antibody and the inhibitor LY294002, respectively, significantly attenuated p53(R248)-mediated ovarian cancer-mesothelial adhesion. These data suggest that the p53(R248) mutant endows ovarian cancer cells with increased adhesiveness and that integrin β4 and Akt signalling are associated with the mutation-enhanced ovarian cancer-mesothelial cell adhesion.

  1. Construction of attenuated Salmonella typhimurium Strain expressing Helicobacter pylori conservative region of adhesin antigen and its immunogenicity

    Institute of Scientific and Technical Information of China (English)

    Yang Bai; Ya-Li Zhang; Ji-De Wang; Zhao-Shan Zhang; Dian-Yuan Zhou

    2004-01-01

    AIM: To construct a non-resistant and attenuated Salmonella typhimurium (S. typhimurium) strain which expresses conservative region of adhesion AB of Helicobacter pylori (H pylori) and evaluate its immunogenicity.METHODS: The AB gene amplified by PCR was inserted into the expression vector pYA248 containing asd gene and through two transformations introduced into the delta Cya, delta Crp, delta Asd attenuated Salmonella typhimurium strain, constructing balanced lethal attenuated Salmonella typhimurium strains X4072 (pYA248-AB). Bridged ELISA method was used to measure the expression of AB antigen in sonic ate and culture supernatant. According to the method described by Meacock, stability of the recombinant was evaluated. Semi-lethal capacity test was used to evaluate the safety of recombinant. The immunogenicity of recombinant was evaluated with animal experiments.RESULTS: The attenuated S. typhimurium X4072 (pYA248-AB) which expresses AB was successfully constructed.Furthermore, bridged ELISA assay showed that the content of AB in recombinant X4072 (pYA248- AB) culture supematant was higher than that was in thallus lyric liquor. And after recombinant X4072 (pYA248- AB) was cultured for 100generations without selection pressure, the entire recombinant bacteria selected randomly could grow, and the AB antigen was defected positive by ELISA. The growth curve of the recombinant bacteria showed that the growth states of X4072 (pYA248) and X4072 (pYA248-AB) were basically consistent. The survival rate of C57BL/6 was still 100%, at 30 d after mice taking X4072 (pYA248-AB) 1.0×1010 cfu orally. Oral immunization of mice with X4072 (pYA248-AB)induced a specific immune response.CONCLUSION: In vitro recombinant plasmid appears to be stable and experiments on animals showed that the recombinant strains were safe and immunogenic in vitro,which providing a new live oral vaccine candidate for protection and care of H pylori infection.

  2. Effects of designed sulfhydryl groups and disulfide bonds into soybean proglycinin on its structural stability and heat-induced gelation.

    Science.gov (United States)

    Adachi, Motoyasu; Chunying, Ho; Utsumi, Shigeru

    2004-09-08

    The gel-forming ability of glycinin is one of soybean's most important functional properties. The proglycinin A1aB1b homotrimer was engineered to introduce sulfhydryl groups and disulfide bonds, and their effects on the structural stability and the heat-induced gelation were evaluated. On the basis of the crystal structure, five mutants were designed and prepared: R161C and F163C forming an interprotomer disulfide bond with the inherent free cysteine residue of Cys377, N116C/P248C forming a new intraprotomer disulfide bond, and N116C and P248C introducing a new sulfhydryl group. Mutants of R161C, F163C, and N116C/P248C formed a new disulfide bond as expected. N116C/P248C was significantly more stable than the wild type against chemical and thermal denaturation and more resistant to alpha-chymotrypsin digestion, whereas F163C showed significantly increased thermal stability. All mutants exhibited greater hardness of heat-induced gels than wild type, and in particular, N116C/P248C gave the hardest gel. This result indicates that it is possible to increase hardness of glycinin gel by introduction of cysteine residues using protein engineering.

  3. Binding-gating coupling in a nondesensitizing alpha7 nicotinic receptor A single channel pharmacological study.

    Science.gov (United States)

    Bernal, José Antonio; Mulet, José; Castillo, Mar; Criado, Manuel; Sala, Salvador; Sala, Francisco

    2009-02-01

    The highly conserved alphaLys145 has been suggested to play an important role in the early steps of activation of the nicotinic acetylcholine receptor (nAChR) by acetylcholine. Both macroscopic and single channel currents were recorded in the slowly desensitizing mutants L248T- and K145A-L248T-alpha7 receptors expressed in Xenopus oocytes. On ACh-evoked currents, substitution of Lys145 by alanine showed the same effects that in wild type receptors: moderately decreased gating function and a more-than-expected loss of ACh potency, thus validating the experimental model. Single channel analysis quantitatively agreed with macroscopic data and revealed that impaired gating function in the double mutant alpha7K145A/L248T is the consequence of a slower opening rate, beta. Several nicotinic agonists were also studied, showing important features. Particularly, dimethylphenylpiperazinium (DMPP), acting as an antagonist in alpha7K145A, became a full agonist in alpha7K145A/L248T. Single channel analysis of DMPP-evoked currents showed effects of Lys145 removal similar to those observed with ACh. Data suggest that alpha7Lys145 facilitates the early steps of channel activation. Moreover, the slowly desensitizing mutant alpha7L248T could be an interesting tool for the study of channel activation in alpha7 receptors. Nevertheless, its extensively altered pharmacology precludes the simple extrapolation of pharmacological data obtained in singly mutated alpha7 receptors.

  4. Purification of Single Wall Carbon Nanotubes as a Function of UV Wavelength, Atmosphere, and Temperature

    Energy Technology Data Exchange (ETDEWEB)

    Kurst, K. E.; Dillon, A. C.; Yang, S.; Lehman, J. H.

    2008-01-01

    We investigate the purification of as-prepared single wall carbon nanotubes (SWCNTs) by exposure to pulsed 193 and 248 nm laser light, as well as lamp wavelengths of 254 and 185 nm. Raman spectroscopy before and after laser exposure indicates the removal of non-nanotube material without modification of the distribution of tube diameter for material exposed to a 248 nm laser, while 193 nm laser light does not selectively oxidize carbon impurities. The mechanism of purification is further considered in the context of atmosphere (oxygen, ozone, nitrogen or partial vacuum) and temperature (measured average and calculated maximum). A mathematical model for pulsed laser heating is used to estimate the maximum temperature achieved during laser excitation. We attribute the purification of nanotube samples to photophysical interactions of the pulsed 248 nm photons in resonance with sp{sup 2} carbon.

  5. Erythrobacter pelagi sp. nov., a member of the family Erythrobacteraceae isolated from the Red Sea

    KAUST Repository

    Wu, H.-x.

    2011-08-05

    A novel Gram-negative, aerobic, catalase- and oxidase-positive, non-sporulating, non-motile, rod-shaped bacterium, designated strain UST081027-248(T), was isolated from seawater of the Red Sea. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain UST081027-248(T) fell within the genus Erythrobacter. Levels of 16S rRNA gene sequence similarity between the novel strain and the type strains of Erythrobacter species ranged from 95.3% (with Erythrobacter gangjinensis) to 98.2% (with Erythrobacter citreus). However, levels of DNA-DNA relatedness between strain UST081027-248(T) and the type strains of closely related species were below 70%. Optimal growth of the isolate occurred in the presence of 2.0% NaCl, at pH 8.0-9.0 and at 28-36 degrees C. The isolate did not produce bacteriochlorophyll a. The predominant cellular fatty acids were C-17:1 omega 6c, summed feature 8 (C-18:1 omega 6c and/or C-18:1 omega 7c) and C-15:0 2-OH. The genomic DNA G+C content of strain UST081027-248(T) was 60.4 mol%. Phenotypic properties and phylogenetic distinctiveness clearly indicated that strain UST081027-248(T) represents a novel species of the genus Erythrobacter, for which the name Erythrobacter pelagi sp. nov. is proposed. The type strain is UST081027-248(T) (=JCM 17468(T)=NRRL 59511(T)).

  6. Addition of positively charged tripeptide to N-terminus of the Fos basic region leucine zipper domain: implications on DNA bending, affinity, and specificity.

    Science.gov (United States)

    Mahmoudi, T; Sarkar, B

    1999-09-01

    GKH-Fos(139-211)/Jun(248-334) (GKH: glycine-lysine-histidine) is a modified Fos/Jun heterodimer designed to contain a metal binding motif in the form of a GKH tripeptide at the amino terminus of Fos bZIP domain dimerized with the Jun basic region leucine zipper (bZIP) domain. We examined the effect of the addition of positively charged GKH motif to the N-terminus of Fos(139-211) on the DNA binding characteristics of the Fos(139-211)/Jun(248-334) heterodimer. Binding studies indicate that while the nonspecific DNA binding affinity of the GKH modified heterodimer increases 4-fold, it specifically binds the activating protein-1 (AP-1) site 6-fold less tightly than the control unmodified counterpart. Furthermore, helical phasing analysis indicates that GKH-Fos(139-211)/Jun(248-334) and control Fos(139-211)/Jun(248-334) both bend the DNA at the AP-1 site toward the minor groove. However, due to the presence of the positively charged GKH motif on Fos, the degree of the induced bend by GKH- Fos(139-211)/Jun(248-334) is greater than that induced by the unmodified Fos/Jun heterodimer. Our results suggest that the unfavorable energetic cost of the increased DNA bending by GKH-Fos(139-211)/Jun(248-334) results in a decrease in both specificity and affinity of binding of the heterodimer to the AP-1 site. These findings may have important implications in protein design as well in our understanding of DNA bending and factors responsible for the functional specificity of different members of the bZIP family of transcription factors.

  7. Biased and constitutive signaling in the CC-chemokine receptor CCR5 by manipulating the interface between transmembrane helices 6 and 7.

    Science.gov (United States)

    Steen, Anne; Thiele, Stefanie; Guo, Dong; Hansen, Lærke S; Frimurer, Thomas M; Rosenkilde, Mette M

    2013-05-03

    The equilibrium state of CCR5 is manipulated here toward either activation or inactivation by introduction of single amino acid substitutions in the transmembrane domains (TMs) 6 and 7. Insertion of a steric hindrance mutation in the center of TM7 (G286F in position VII:09/7.42) resulted in biased signaling. Thus, β-arrestin recruitment was eliminated, whereas constitutive activity was observed in Gαi-mediated signaling. Furthermore, the CCR5 antagonist aplaviroc was converted to a full agonist (a so-called efficacy switch). Computational modeling revealed that the position of the 7TM receptor-conserved Trp in TM6 (Trp-248 in position VI:13/6.48, part of the CWXP motif) was influenced by the G286F mutation, causing Trp-248 to change orientation away from TM7. The essential role of Trp-248 in CCR5 activation was supported by complete inactivity of W248A-CCR5 despite maintaining chemokine binding. Furthermore, replacing Trp-248 with a smaller aromatic amino acid (Tyr/Phe) impaired the β-arrestin recruitment, yet with maintained G protein activity (biased signaling); also, here aplaviroc switched to a full agonist. Thus, the altered positioning of Trp-248, induced by G286F, led to a constraint of G protein active, but β-arrestin inactive and thus biased, CCR5 conformation. These results provide important information on the molecular interplay and impact of TM6 and TM7 for CCR5 activity, which may be extrapolated to other chemokine receptors and possibly to other 7TM receptors.

  8. 比值-导数光谱法快速测定香草醛%Rapidly Determination of Vanillin by Ratio-derivative Spectrophotometry

    Institute of Scientific and Technical Information of China (English)

    姚丽平; 陈元彩

    2013-01-01

    文章用比值-导数光谱法测定香草醛的含量.实验结果表明,香草醛木素溶液在pH≤7时香草醛在230 nm处有吸收,在pH>7时在248 nm处有吸收.根据不同pH值和不同浓度条件下香草醛木素溶液的比值-导数光谱,说明在230 nm处的光谱信号在pH≤7不受pH值影响,248 nm处的光谱信号在pH>7不受pH值影响.在230 nm和248 nm处的光谱信号对浓度的变化较为敏感,在此两处吸收值可用于香草醛的测定.%Ratio-derivative spectrometry was used for determination of vanillin content. Analysis results indicated that when pH ≤7 vanillin lignin has absorption at 230 nm and when pH>7 vanillin lignin has absorption at 248 nm. Ratio derivative spectrum of vanillin under different pH and different concentrations indicated that when pH ≤ 7 the spectrum at 230 nm would not suffer from pH effect, when pH>7 the spectrum at 248 nm would not suffer from pH effect. The signals at 230 nm and 248 nm in the spectrum are more sensitive to the change of concentrations, thus the two values can be used for the determination of absorption.

  9. Settlement induction of Acropora palmata planulae by a GLW-amide neuropeptide

    Science.gov (United States)

    Erwin, P. M.; Szmant, A. M.

    2010-12-01

    Complex environmental cues dictate the settlement of coral planulae in situ; however, simple artificial cues may be all that is required to induce settlement of ex situ larval cultures for reef re-seeding and restoration projects. Neuropeptides that transmit settlement signals and initiate the metamorphic cascade have been isolated from hydrozoan taxa and shown to induce metamorphosis of reef-building Acropora spp. in the Indo-Pacific, providing a reliable and efficient settlement cue. Here, the metamorphic activity of six GLW-amide cnidarian neuropeptides was tested on larvae of the Caribbean corals Acropora palmata, Montastraea faveolata and Favia fragum. A. palmata planulae were induced to settle by the exogenous application of the neuropeptide Hym-248 (concentrations ≥1 × 10-6 M), achieving 40-80% attachment and 100% metamorphosis of competent planulae (≥6 days post-fertilization) during two spawning seasons; the remaining neuropeptides exhibited no activity. Hym-248 exposure rapidly altered larval swimming behavior (96% metamorphosis after 6 h. In contrast , M. faveolata and F. fragum planulae did not respond to any GLW-amides tested, suggesting a high specificity of neuropeptide activators on lower taxonomic scales in corals. Subsequent experiments for A. palmata revealed that (1) the presence of a biofilm did not enhance attachment efficiency when coupled with Hym-248 treatment, (2) neuropeptide-induced settlement had no negative effects on early life-history developmental processes: zooxanthellae acquisition and skeletal secretion occurred within 12 days, colonial growth occurred within 36 days, and (3) Hym-248 solutions maintained metamorphic activity following storage at room temperature (10 days), indicating its utility in remote field settings. These results corroborate previous studies on Indo-Pacific Acropora spp. and extend the known metamorphic activity of Hym-248 to Caribbean acroporids. Hym-248 allows for directed and reliable settlement of

  10. Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape

    Science.gov (United States)

    Elliott, Debra H.; Rouelle, Julie; Smira, Ashley; Ndabambi, Nonkululeko; Druz, Aliaksandr; Williamson, Carolyn

    2017-01-01

    A comprehensive understanding of the regions on HIV-1 envelope trimers targeted by broadly neutralizing antibodies may contribute to rational design of an HIV-1 vaccine. We previously identified a participant in the CAPRISA cohort, CAP248, who developed trimer-specific antibodies capable of neutralizing 60% of heterologous viruses at three years post-infection. Here, we report the isolation by B cell culture of monoclonal antibody CAP248-2B, which targets a novel membrane proximal epitope including elements of gp120 and gp41. Despite low maximum inhibition plateaus, often below 50% inhibitory concentrations, the breadth of CAP248-2B significantly correlated with donor plasma. Site-directed mutagenesis, X-ray crystallography, and negative-stain electron microscopy 3D reconstructions revealed how CAP248-2B recognizes a cleavage-dependent epitope that includes the gp120 C terminus. While this epitope is distinct, it overlapped in parts of gp41 with the epitopes of broadly neutralizing antibodies PGT151, VRC34, 35O22, 3BC315, and 10E8. CAP248-2B has a conformationally variable paratope with an unusually long 19 amino acid light chain third complementarity determining region. Two phenylalanines at the loop apex were predicted by docking and mutagenesis data to interact with the viral membrane. Neutralization by CAP248-2B is not dependent on any single glycan proximal to its epitope, and low neutralization plateaus could not be completely explained by N- or O-linked glycosylation pathway inhibitors, furin co-transfection, or pre-incubation with soluble CD4. Viral escape from CAP248-2B involved a cluster of rare mutations in the gp120-gp41 cleavage sites. Simultaneous introduction of these mutations into heterologous viruses abrogated neutralization by CAP248-2B, but enhanced neutralization sensitivity to 35O22, 4E10, and 10E8 by 10-100-fold. Altogether, this study expands the region of the HIV-1 gp120-gp41 quaternary interface that is a target for broadly neutralizing

  11. Effects of Nitrogen Fertilization and Soil Inoculation of Sulfur-Oxidizing or Nitrogen-Fixing Bacteria on Onion Plant Growth and Yield

    OpenAIRE

    2011-01-01

    A field experiment was conducted in a newly reclaimed soil at El-Saff region, El-Giza Governorate, Egypt to study the effects of different rates of nitrogen (N: 62 to 248 kg ha-1) with or without soil inoculation of sulfur- (S-) oxidizing bacteria (SoxB) and combined inoculation of SoxB and N-fixing bacteria (NFxB) on yield, quality and nutritional status of onion (Allium cepa L., “Giza 20”). Elemental S at 620 kg ha-1 was applied to all treatments. Application of N at 62, 124, and 248 kg ha...

  12. Alternatives to the Judicially Promulgated Feres Doctrine

    Science.gov (United States)

    2007-04-01

    assaulted an Army sergeant. Lieutenant Locke also allegedly told the team that pepper spray had failed to subdue the "detainee." The evidence suggests that...States, 248 F.3d 863, 869 (9th Cir. 2001) ( Ferguson , J., dissenting). Critics of this line of thought have pointed to the fact that, even though more...2674, 2680 (2004). 274 Costo, 248 F.3d at 871 ( Ferguson , J., dissenting). See Schoemer v. United States, 59 F.3d 26, 28 (5th Cir. 1995); Pringle v

  13. Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape

    Energy Technology Data Exchange (ETDEWEB)

    Wibmer, Constantinos Kurt; Gorman, Jason; Ozorowski, Gabriel; Bhiman, Jinal N.; Sheward, Daniel J.; Elliott, Debra H.; Rouelle, Julie; Smira, Ashley; Joyce, M. Gordon; Ndabambi, Nonkululeko; Druz, Aliaksandr; Asokan, Mangai; Burton, Dennis R.; Connors, Mark; Abdool Karim, Salim S.; Mascola, John R.; Robinson, James E.; Ward, Andrew B.; Williamson, Carolyn; Kwong, Peter D.; Morris, Lynn; Moore, Penny L.; Desrosiers, Ronald C.

    2017-01-11

    A comprehensive understanding of the regions on HIV-1 envelope trimers targeted by broadly neutralizing antibodies may contribute to rational design of an HIV-1 vaccine. We previously identified a participant in the CAPRISA cohort, CAP248, who developed trimer-specific antibodies capable of neutralizing 60% of heterologous viruses at three years post-infection. Here, we report the isolation by B cell culture of monoclonal antibody CAP248-2B, which targets a novel membrane proximal epitope including elements of gp120 and gp41. Despite low maximum inhibition plateaus, often below 50% inhibitory concentrations, the breadth of CAP248-2B significantly correlated with donor plasma. Site-directed mutagenesis, X-ray crystallography, and negative-stain electron microscopy 3D reconstructions revealed how CAP248-2B recognizes a cleavage-dependent epitope that includes the gp120 C terminus. While this epitope is distinct, it overlapped in parts of gp41 with the epitopes of broadly neutralizing antibodies PGT151, VRC34, 35O22, 3BC315, and 10E8. CAP248-2B has a conformationally variable paratope with an unusually long 19 amino acid light chain third complementarity determining region. Two phenylalanines at the loop apex were predicted by docking and mutagenesis data to interact with the viral membrane. Neutralization by CAP248-2B is not dependent on any single glycan proximal to its epitope, and low neutralization plateaus could not be completely explained by N- or O-linked glycosylation pathway inhibitors, furin co-transfection, or pre-incubation with soluble CD4. Viral escape from CAP248-2B involved a cluster of rare mutations in the gp120-gp41 cleavage sites. Simultaneous introduction of these mutations into heterologous viruses abrogated neutralization by CAP248-2B, but enhanced neutralization sensitivity to 35O22, 4E10, and 10E8 by 10-100-fold. Altogether, this study expands the region of the HIV-1 gp120-gp41 quaternary interface that is a target for broadly neutralizing

  14. How to build a sustainable business for rural electrification: A study of business models for rural electrification in India

    OpenAIRE

    Medbø, Eirik Gjelsvik; Eithun, Julie Foyn

    2013-01-01

    More than 1.4 billion people lack access to electricity (The International Energy Agency (IEA) 2010, p.248; World Bank 2008; Legros et.al 2009). With the current electrification policy, the total number of people lacking energy will stay at 1.2 billion people in 2030, due to the high population growth (IEA 2010, p.248). This is especially prominent in Sub-Saharan Africa and India, where population growth exceeds electrification rates (Barnes & Foley 2004).There is a strong correlation bet...

  15. Bright Photoelectron Beams Emitted From Excimer-Laser Illuminated LaB6

    Science.gov (United States)

    Oettinger, Peter E.

    1988-12-01

    Lanthanum hexaboride has traditionally been used as a high-temperature thermionic emitter of electrons. This material, whose work function for a sintered multicrystalline composition is nominally 2.6 eV, appears to be a reasonably good photoemitter when irradiated by UV light. A quantum efficiency of 10-3 was recorded for photoemission at a 193 nm (ArF) incident wavelength. At least 20 A/cm2 were observed at 193 nm, 248 nm (KrF) and 308 (XeC1). Beam brightness appears to be a minimum of 4 x 105 A/cm2-rad2 at 248 nm.

  16. EST Table: FS905878 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available :-1|gene:AGAP006132 10/09/10 n.h 10/09/10 41 %/248 aa gi|91078536|ref|XP_970577.1| PREDICTED: similar to ganglios...FS905878 E_FL_fufe_06H02_F_0 11/12/09 n.h 10/09/28 41 %/248 aa ref|XP_970577.1| PREDICTED: similar to gangli...oside-induced differentiation-associated-protein 1 [Tribolium castaneum] gb|EFA0047

  17. Strangeness -2 studies at KEK

    Energy Technology Data Exchange (ETDEWEB)

    Nakazawa, K. [Gifu Univ. (Japan). Dept. of Physics

    1998-08-24

    Studies of double-strangeness (S=-2) systems at KEK are summarized. At KEK, beam exposures have been completed in three experiments, namely PS-E176, E224, and E248. The first two experiments provide interesting information on the {Xi}-N interaction, which will be discussed. In E248, counter alignment calibrations are in progress. A fourth experiment, PS-E373, is waiting for its first period of beam exposure in February 1998 and should provide at least ten times better statistics on S=-2 systems than did E176 and E224. (orig.) 14 refs.

  18. Strangeness -2 studies at KEK

    Science.gov (United States)

    Nakazawa, Kazuma

    1998-08-01

    Studies of double-strangeness (S=-2) systems at KEK are summarized. At KEK, beam exposures have been completed in three experiments, namely PS-E176, E224, and E248. The first two experiments provide interesting information on the Ξ-N interaction, which will be discussed. In E248, counter alignment calibrations are in progress. A fourth experiment, PS-E373, is waiting for its first period of beam exposure in February 1998 and should provide at least ten times better statistics on S=-2 systems than did E176 and E224.

  19. Photophysical and photochemical processes of riboflavin (vi-tamin B2) by means of the transient absorption spectra in aqueous solution

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Using time-resolved techniques of 337 and 248 nm laser flashphotolysis, the photophysical and photochemical processes of riboflavin (RF, vitamin B2) were studied in detail in aqueous solution. The excited triplet state of riboflavin (3RF*) was produced with 337 nm laser, while under 248 nm irradiation, both 3RF* and hydrated electron () formed from photoionization could be detected. Photobiological implications have been inferred on the basis of reactivity of 3RF* including energy transfer, electron transfer and hydrogen abstraction. The RF·+ was gene- rated by oxidation of SO4·- radical with the aim of confirming the results of photolysis

  20. Possible Way to Synthesize Superheavy Element Z=117

    CERN Document Server

    Zhao-Qing, Feng; Ming-Hui, Huang; Zai-Guo, Gan; Nan, Wang; Jun-Qing, Li

    2007-01-01

    Within the framework of the dinuclear system model, the production of superheavy element Z=117 in possible projectile-target combinations is analyzed systematically. The calculated results show that the production cross sections are strongly dependent on the reaction systems. Optimal combinations, corresponding excitation energies and evaporation channels are proposed in this letter, such as the isotopes ^{248,249}Bk in ^{48}Ca induced reactions in 3n evaporation channels and the reactions ^{45}Sc+^{246,248}Cm in 3n and 4n channels, and the system ^{51}V+^{244}Pu in 3n channel.

  1. Possible Way to Synthesize Superheavy Element Z = 117

    Institute of Scientific and Technical Information of China (English)

    FENG Zhao-Qing; JIN Gen-Ming; HUANG Ming-Hui; GAN Zai-Guo; WANG Nan; LI Jun-Qing

    2007-01-01

    Within the framework of the dinuclear system model, the production of superheavy element Z = 117 in possible projectile-target combinations is analysed systematically. The calculated results show that the production cross sections are strongly dependent on the reaction systems. Optimal combinations, corresponding excitation energies and evaporation channels are proposed, such as the isotopes 248,249Bk in 48Ca induced reactions in 3n evaporation channels and the reactions 45Sc+246,248Cm in 3n and 4n channels, and the system 51V+244pu in 3n channel.

  2. Pulmonary hemorrhage complicating radiofrequency ablation, from mild hemoptysis to life-threatening pattern

    Energy Technology Data Exchange (ETDEWEB)

    Nour-Eldin, Nour-Eldin A.; Naguib, Nagy N.N.; Mack, Martin; Abskharon, John E.; Vogl, Thomas J. [Johann Wolfgang Goethe-University Hospital, Institute for Diagnostic and Interventional Radiology, Frankfurt am Main (Germany)

    2011-01-15

    To assess risk factors and the extent of pulmonary hemorrhage complicating radiofrequency ablation (RFA) of pulmonary neoplasms. This retrospective study involved 248 ablation sessions for lung tumors (20 primary lesions and 228 metastatic lesions) in 164 patients (mean age 59.7 years, SD: 10.2). Both unipolar and bipolar radiofrequency systems were used under CT fluoroscopic guidance. Extent and underlying factors associated with development of pulmonary hemorrhage were analyzed. Incidence of intra-parenchymal pulmonary hemorrhage, pleural effusion, and hemoptysis were 17.7% (44/248 sessions), 4% (8/248 sessions), and 16.1% (40/248 sessions), respectively. Death because of massive bleeding occurred in one session (0.4%). Significant risk factors associated with intra-parenchymal hemorrhage included: lesions of <1.5 cm diameter (P = 0.007); basal and middle lung zone lesions (P = 0.026); increased needle track distance traversing the lung parenchyma >2.5 cm (P = 0.0017); traversing pulmonary vessels in the track of ablation (P < 0.001); and the use of multi-tined electrodes (P = 0.004). Concomitant incidence of pulmonary hemorrhage and pneumothorax was 29.2% (14/48 sessions). While typically safe, RFA of pulmonary neoplasms can result in pulmonary hemorrhage ranging from mild to life-threatening. Management of this complication is mainly preventive through adequate patient selection for ablation therapy and exclusion of technically avoidable risk factors. (orig.)

  3. The Language Growth of Spanish-Speaking English Language Learners

    Science.gov (United States)

    Rojas, Raul; Iglesias, Aquiles

    2013-01-01

    Although the research literature regarding language growth trajectories is burgeoning, the shape and direction of English Language Learners' (ELLs) language growth trajectories are largely not known. This study used growth curve modeling to determine the shape of ELLs' language growth trajectories across 12,248 oral narrative language samples…

  4. Dysfunctional Relationship Beliefs in Parent-Late Adolescent Relationship and Conflict Resolution Behaviors

    Science.gov (United States)

    Hamamci, Zeynep

    2007-01-01

    The purpose of this study is to investigate the role of dysfunctional relationships beliefs on both the perceptions of their relationships with the parents and conflict resolution behaviors of late adolescence. The sample was consisted of 372 Turkish university students (248 women and 124 men). Interpersonal Cognitive Distortions Scale,…

  5. AcEST: BP916470 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 30 6.4 sp|Q00496|BXE_CLOBO Botulinum neurotoxin type E OS=Clostridium b... 30 6.5 >sp|P83006|PAFA2_RAT Plat... ++R L + P +LKT+SS PC+D Sbjct: 204 LIQPEGISEIDTAKKLLEYHRHIIRILPSYPKILKTISSDQPCVD 248 >sp|Q00496|BXE_CLOBO Botulinum neurotoxi

  6. A study on matrix assisted pulsed evaporation (MAPLE) of organic materials

    DEFF Research Database (Denmark)

    Matei, Andreea; Canulescu, Stela; Constantinescu, Catalin;

    2012-01-01

    Organic films can be produced either by MAPLE or directly by PLD (Pulsed laser deposition). For a reasonable deposition rate of ng/cm2 per pulse for film production by MAPLE a fluence of 1-1.5 J/cm2 is required at the laser wavelength of 355 nm, while the fluence can be considerably lower at 248 ...

  7. Endemic Hepatitis E in two Nordic Countries

    DEFF Research Database (Denmark)

    Norder, H.; Sundqvist, L.; Magnusson, L.

    2009-01-01

    Antibodies against hepatitis E virus (anti-HEV) were found in 248 Swedish and Danish patients between 1993 and 2007. Most patients were symptomatic and tested for anti-HEV due to travel abroad. Among patients with known country of infection, most were infected in Asia, mainly on the Indian...

  8. USA Today: Accentuating the Positive: A Study of the Gannett Flagship Newspaper.

    Science.gov (United States)

    Wright, William F.

    To investigate whether "USA Today" emphasizes "good news" over "bad news," a study was conducted using 10 randomly selected adults in State College, Pennsylvania, over an 11-week period in 1985. Subjects were asked to rate 248 stories over 45 pages of main news columns in 10 issues on a scale ranging from 1 (very negative news) to 7 (very positive…

  9. EST Table: FS904141 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available ar to 2-aminoethanethiol (cysteamine) dioxygenase [Tribolium castaneum] gb|EFA09634.1| hypothetical protein ...10 33 %/248 aa gnl|Amel|GB12350-PA 10/09/10 35 %/238 aa gi|91090992|ref|XP_974899.1| PREDICTED: similar to 2-aminoethanethiol (cystea

  10. 24 CFR 982.201 - Eligibility and targeting.

    Science.gov (United States)

    2010-04-01

    ... multifamily units) project. (Section 8(o)(4)(D) of the 1937 Act (42 U.S.C. 1437f(o)(4)(D)); (v) A low-income... residing in a project subject to a resident homeownership program under § 248.173 of this title. (2) Income...) (crime by family members)....

  11. Actores protectores que favorecen la resiliencia de estudiantes para lograr su permanencia en la licenciatura en ciencias de la educacion de la UATX /

    OpenAIRE

    Velazquez Flores, Guadalupe

    2012-01-01

     tesis que para obtener el grado de Doctorado en Pedagogía, presenta Guadalupe Velazquez Flores ; tutora principal de tesis Dora Elena Marin Mendez248 páginas : ilustracionesDoctorado en Pedagogía Universidad Nacional Autónoma de México, 2012 Programa de Posgrado en Pedagogía

  12. Measurement of Hot Electron Spectrum During the Interaction of Ultrashort Pulse UV Laser With Solid Target

    Institute of Scientific and Technical Information of China (English)

    LIYe-jun; SHANYu-sheng; ZHANGJi; ZHANGHai-feng; TANGXiu-zhang; WANGLei-jian

    2003-01-01

    The hot electron spectrum was measured using electron magnetic spectrometer through the irradiation of solid Cu target by an intense, UV (248 nm) femtosecond (440 fs) laser pulse with free pre-pulse, and the intensity of laser is 1017 W/cm2. We find the electron spectrum presents two temperatures Maxwellian distribution.

  13. Exploring Interpersonal Compatibility in Groups.

    Science.gov (United States)

    Keyton, Joann

    This study investigated William Schutz's three-dimensional theory of interpersonal behavior and compatibility (FIRO) to determine its validity as a group measure of compatibility. Data were collected from 248 students enrolled in a multi-section course in small group communications at a large midwestern university. Subjects self-selected…

  14. Petrographic studies on a newly discovered Indo-Arabian stone anchor from the Gulf of Kachchh, Gujarat: Implications for source area

    Digital Repository Service at National Institute of Oceanography (India)

    Tripati, S.; Mudholkar, A.; Khedekar, V.

    of soil properties in agricultural farm and its application in pre- dicting surface map of hydraulic property. Curr. Sci., 2008, 95, 937–945. 21. Davis, B. M., Uses and abuses of cross-validation in geostatistics. Math. Geol., 1987, 19, 241–248. 22...

  15. Inlet Processes at Eel Pond, Falmouth, Massachusetts.

    Science.gov (United States)

    1984-10-01

    MA 02062 AGC Aero- Graphics Corp. Box 248, Bohemia, NY 11716 AMS Aero-Marine Surveys 38 Green Street, New London, CT 06320 AIT Air Image Technology...Transport (Example)0 Bagn old, R. A. , The Phys ics of Blown Sai d an d Dese rt Dun es, Methuen & Co., Ltd. , Lmndon, 1954.p 2/Zbgg, A. W., Whd Tunnel Studies

  16. Measurement of alcohol hangover severity : development of the Alcohol Hangover Severity Scale (AHSS)

    NARCIS (Netherlands)

    Penning, Renske; McKinney, Adele; Bus, Lucien D.; Olivier, Berend; Slot, Karin; Verster, Joris C.

    2013-01-01

    This study aims to develop a new alcohol hangover symptom severity scale and compare its effectiveness with the Hangover Symptoms Scale (HSS), the Acute Hangover Scale (AHS), and a one-item hangover score. Data from 1,410 Dutch students (Penning et al., Alcohol Alcohol 47:248-252, 2012) on the sever

  17. Incidence of osteonecrosis after renal transplantation

    NARCIS (Netherlands)

    H.J. Metselaar (Herold); van Steenberge, J.P. (J. P.); A.B. Bijnen (Bart); J. Jeekel (Hans); B. van Linge (Bert); W. Weimar (Willem)

    1985-01-01

    textabstractThe incidence of osteonecrosis was 24% in 248 patients who had received 262 kidney transplants 1971-1982. However, based only on patients at risk, i.e. alive with functioning transplants, the incidence at 1, 3 and 6 years was found to be 13, 27 and 36%; after six years no new cases were

  18. EV71-IgM胶体金法在手足口病早期诊断的价值

    Institute of Scientific and Technical Information of China (English)

    甘超

    2013-01-01

    目的:评价胶体法检测EV71 IgM抗体与RT-PCR法检测EV71病毒核酸在手足口病诊断的优劣.方法:标本选取248例手足口疑似病例,分别采用血清金标法检测EV71肠道病毒IgM抗体,咽拭RT-PCR法检测EV71-RNA.结果:2012年3月~2012年4月对248例疑似病例进行胶体金法检测,EV71阳性率为16.94%(42/248),RT-PCR法检测阳性率为19.35%(48/248).其中2例金标法检测阳性采用RT-PCR法检测为阴性.EV71胶体金法快速检测试剂的特异度为96.15%,灵敏度为83.33%.结论:EV71胶体金法可作为EV71感染的初筛早期快检,在临床诊治和流感爆发疫情处理上具有重要意义.

  19. Longitudinal Study on Reciprocity between Personality Traits and Parenting Stress

    Science.gov (United States)

    Rantanen, Johanna; Tillemann, Kati; Metsäpelto, Riitta-Leena; Kokko, Katja; Pulkkinen, Lea

    2015-01-01

    Reciprocal associations between the Big Five personality traits and parenting stress--including both parents' feelings of their distress and perception of their incompetence as parents--were studied with 248 participants (49% of which were males). Longitudinal data, collected at ages 33/36, 42 and 50 years, were used. Cross-lagged path…

  20. An Investigation of Big Five Personality Traits and Career Decidedness among Early and Middle Adolescents

    Science.gov (United States)

    Lounsbury, John W.; Hutchens, Teresa; Loveland, James M.

    2005-01-01

    Big Five personality traits were analyzed in relation to career decidedness among adolescents in middle and high school. Participants were 248 7th-grade, 321 10th-grade, and 282 12th-grade students. As hypothesized, Conscientiousness was positively and significantly correlated with career decidedness in all three grades. Openness and Agreeableness…

  1. 30 CFR 77.403-1 - Mobile equipment; rollover protective structures (ROPS).

    Science.gov (United States)

    2010-07-01

    ....1-73, or Military Standard MIL-STD 248, or the equivalent thereof. (g) Seat belts required by § 77... J 397a, “Deflection Limiting Volume for Laboratory Evaluation of Rollover Protective Structures (ROPS) and Falling Object Protective Structures (FOPS) of Construction and Industrial Vehicles” and...

  2. Clinical experience with telemetric intracranial pressure monitoring in a Danish neurosurgical center

    DEFF Research Database (Denmark)

    Lilja, Alexander; Andresen, Morten; Hadi, Amer

    2014-01-01

    kinds of hydrocephalus, seven patients had idiopathic intracranial hypertension (IIH) and three patients had normal pressure hydrocephalus (NPH). Fifteen patients had a shunt prior to implantation. Median duration of implantation was 248 (49-666) days and median duration from implantation to last...

  3. Pattern Definition with DUV-Lithography at DTU Danchip

    DEFF Research Database (Denmark)

    Keil, Matthias; Khomtchenko, Elena; Nyholt, Henrik;

    2014-01-01

    Deep ultra violet (DUV) illumination generated with the help of a KrF laser can be utilized to produce components having sizes of some hundreds of nanometers. This light source with its 248nm wavelength is exploited in the DUV-lithography equipment at DTU Danchip in order to fill the resolution g...

  4. Performance Appraisal Interview: A Review of Research.

    Science.gov (United States)

    1987-01-01

    considering subordinates’ effort as well as the results achieved when evaluating performance ( Dornbusch & Scott, 1975; Landy et al. 1978; Morran & Stockton...Journal of Applied Psychology, 66, 248-251. Dornbusch , S.M. & Scott, W.R. (1975). Evaluation and the exercise of authority. San Francisco: Josey-Bass

  5. 78 FR 42544 - Outer Continental Shelf (OCS), Gulf of Mexico (GOM), Oil and Gas Lease Sale, Western Planning...

    Science.gov (United States)

    2013-07-16

    ... Bureau of Ocean Energy Management Outer Continental Shelf (OCS), Gulf of Mexico (GOM), Oil and Gas Lease Sale, Western Planning Area (WPA) Lease Sales 238, 246, and 248 MMAA104000 AGENCY: Bureau of Ocean... Supplemental EIS for proposed WPA lease sales beginning with Lease Sale 238 (WPA Lease Sales 238, 246, and...

  6. Drug: D04039 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D04039 Drug Eprodisate disodium (USAN) C3H6O6S2. 2Na 247.9401 248.1857 D04039.gif T...reatment of secondary (AA) amyloidosis CAS: 36589-58-9 PubChem: 47206004 LigandBox: D04039 NIKKAJI: J534.156

  7. Supervision Practices and Teachers' Satisfaction in Public Secondary Schools: Malaysia and China

    Science.gov (United States)

    Hamzah, Mohd Izham Mohd; Wei, Yan; Ahmad, Jamil; Hamid, Aida Hanim A.; Mansor, Azlin Norhaini

    2013-01-01

    The purpose of this study is to explore supervision practices among school management teams and teachers' satisfaction in secondary schools in Kuala Lumpur, Malaysia and He Fei, China. The samples consist of 248 managers and 367 teachers in Kuala Lumpur, and 175 managers and 346 teachers in He Fei. The study indicates that the level of supervision…

  8. Gclust Server: 68268 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 68268 CEL_F09E10.3_25147288 Cluster Sequences Related Sequences(625) 248 dhs-25: De...Hydrogenases, Short chain family member (dhs-25) 1 9.98e-01 0.0 0.0 0.0 0.0 0.0 12.5 Show 68268 Cluster ID 68268

  9. Protein cold adaptation : Role of physico-chemical parameters in adaptation of proteins to low temperatures

    NARCIS (Netherlands)

    Shokrollahzade, Soheila; Sharifi, Fatemeh; Vaseghi, Akbar; Faridounnia, Maryam; Jahandideh, Samad

    2015-01-01

    During years 2007 and 2008, we published three papers (Jahandideh, 2007a, JTB, 246, 159-166; Jahandideh, 2007b, JTB, 248, 721-726; Jahandideh, 2008, JTB, 255, 113-118) investigating sequence and structural parameters in adaptation of proteins to low temperatures. Our studies revealed important featu

  10. A Model of Reading Comprehension in Chinese Elementary School Children

    Science.gov (United States)

    Yeung, Pui-sze; Ho, Connie Suk-han; Chan, David Wai-ock; Chung, Kevin Kien-hoa; Wong, Yau-kai

    2013-01-01

    The relationships of reading-related skills (rapid naming, morphological awareness, syntactic skills, discourse skills, and verbal working memory) and word reading to reading comprehension were examined among 248 Chinese fourth graders in Hong Kong. Multiple regression analysis results showed that syntactic skills (word order knowledge,…

  11. Korean and Foreign Students' Perceptions of the Teacher's Role in a Multicultural Online Learning Environment in Korea

    Science.gov (United States)

    Lee, Dong Yub

    2011-01-01

    This study investigated Korean and foreign students' perception of the teacher's role in multicultural online learning environments in Korea. On the basis of a literature review, a survey questionnaire was developed and piloted with 248 university students in Korea. The questionnaire was subsequently modified on the basis of the results of the…

  12. Facial Expressions of Emotion and the Assessment of Performance

    Science.gov (United States)

    2010-07-01

    is associated with energy mobilization, low subjective stress, and enhanced task performance (Tomaka, & Palacios- Esquivel , 1997). Thus, emotional...of Personality and Social Psychology, 66, 248-260. Tomaka, J., & Palacios- Esquivel , R. L. (1997). Motivational systems and stress-related

  13. 75 FR 1697 - Airworthiness Directives; Dassault-Aviation Model Falcon 7X Airplanes

    Science.gov (United States)

    2010-01-13

    ...- altimeter lock-up is in progress. In the meantime, Dassault Aviation has developed an operational procedure... Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2009-1252; Directorate Identifier 2009-NM-248-AD; Amendment 39-16173; AD 2010-02-02] RIN 2120-AA64 Airworthiness Directives;...

  14. Sex Differences in Developmental Trends of Suicide Ideation, Plans, and Attempts among European American Adolescents

    Science.gov (United States)

    Boeninger, Daria K.; Masyn, Katherine E.; Feldman, Betsy J.; Conger, Rand D.

    2010-01-01

    Although suicide ideation, plans, and attempts increase during adolescence, it remains unclear whether boys' and girls' risk for these outcomes peaks at different ages. We used longitudinal categorical data ("never," "once," "2+ times") from the Family Transitions Project (N = 1,248 rural European Americans, ages 11-19) to investigate whether…

  15. Application of Multivariable Control Theory to Aircraft Control Laws. Final Report: Multivariable Control Design Guidelines.

    Science.gov (United States)

    1996-05-01

    assessment of stability is possible using the circle criterion [Safonov 1978], but this method is very conservative. 248 Im Stable -I/N (a) Re Figure B.16...Safonov, M. G. and M. Athans, "A Multiloop Gen- eralization of the Circle Criterion ," Twelfth Asilo- mar Conference on Circuits, Systems, and Comput

  16. Domain Modeling: NP_004724.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available BETP FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND SUBSTRATE p2wita_ chr3/NP_004724.1/NP_004724.1_holo_70-544.pdb swppa 225Y,226F,227L,228G,230V,247F,248Q,321K,411Y,412I,415L BET 0 ...

  17. OSA Trends in Optics and Photonics Series. Volume 13: Ultrafast Electronics and Optoelectronics

    Science.gov (United States)

    1997-01-01

    Ramadas M. R. Pillai in construction of the Er/Yb optical amplifier, and that of David 0. Ca- plan in optically measuring the various fiber lengths...operation of the nonlinear fiber loop mirror," Opt. Lett., 1990, 15, pp. 248-250. [5] D. M. Patrick , A. D. Ellis, and D. M. Spirit, "Bit-rate flexible all

  18. Insight into band positions and inter-particle electron transfer dynamics between CdS nanoclusters and spatially isolated TiO2 dispersed in cubic MCM-48 mesoporous materials: a highly efficient system for photocatalytic hydrogen evolution under visible light illumination

    NARCIS (Netherlands)

    Peng, R.; Lin, C.K.; Baltrusaitis, J.; Wu, C.M.; Dimitrijevic, N.M.; Rajh, T.; May, S.; Koodali, R.T.

    2014-01-01

    CdS incorporated Si-MCM-48 and Ti-MCM-48 cubic phased mesoporous photocatalysts were prepared by a two-step modification synthetic approach under relatively mild conditions. A highly efficient (24.8%, apparent quantum yield (AQY)) photocatalyst for visible light (λ > 400 nm) enabled solar hydrogen e

  19. What is a Spectrum?

    CERN Document Server

    Bolton, Adam S; Brownstein, Joel; Pandey, Parul; Schlegel, David; Shu, Yiping

    2011-01-01

    This contribution describes the "spectro-perfectionism" algorithm of Bolton & Schlegel (2010, PASP, 122, 248) that is being implemented within the Baryon Oscillation Spectroscopic Survey (BOSS) of the Sloan Digital Sky Survey III (SDSS-III), in terms of its potential to deliver Poisson-limited sky subtraction and lossless compression of the input spectrum likelihood functional given raw CCD data.

  20. Computer Generated Hologram and Magneto-Optic Spatial Light Modulator for Optical Pattern Recognition.

    Science.gov (United States)

    1987-12-01

    must become familiar with the C programming language, a C compiler (Computer Innovations C86 is installed on the Zenith 248 which is interfaced with...a library. The - libraries C86S2S and TARGA must also be included since C86S2S contains all the C programming functions and the TARGA library

  1. Synonymical remarks about Mallodon jejunum, Pascoe

    NARCIS (Netherlands)

    Neervoort van de Poll, J.R.H.

    1886-01-01

    Mallodon jejunum Pascoe (Journal of Entomology, II, 1864, p. 248) became some years afterwards the type of the genus Brephilydia Pascoe (Annals and Magazine of Natural History. 4th ser., vol. IV, 1871, pl. 13, fig. 6 & 6a); in the Munich Catalogue the genus Brephilydia is placed as a synonym of the

  2. Final Environmental Impact Statement. Relocation of the 146th Tactical Airlift Wing of the California Air National Guard. Volume 1. EIS Text

    Science.gov (United States)

    1985-08-01

    Chino Airport 45,682 Ontario International Airport 122,813 TOTAL 607,859 AF Plant #4 2 a 44,248 Lancaster/Fox Field 72,131 Edwards AFB 111,000 Agua ...contamination of potable waters. Temporary skimmers or dams shall be constructed in the area of a culvert in one of the main drainage ditches to prevent

  3. An Investigation of Personality Traits in Relation to Adolescent School Absenteeism.

    Science.gov (United States)

    Lounsbury, John W.; Steel, Robert P.; Loveland, James M.; Gibson, Lucy W.

    2004-01-01

    We examined the Big Five personality traits of Agreeableness, Conscientiousness, Emotional Stability, Extraversion, and Openness, as well as four narrower traits of Aggression, Optimism, Tough-Mindedness, and Work Drive in relation to absences from school for middle- and high-school students. Participants were 248 seventh grade students, 321 tenth…

  4. The Soundtrack of Recklessness: Musical Preferences among Adolescents.

    Science.gov (United States)

    Arnett, Jeffrey

    1992-01-01

    Adolescents (n=248) with various musical preferences were compared. Adolescents who preferred hard rock or heavy metal music reported higher rates of reckless behavior and were associated with higher levels of sensation seeking, negative family relationships, and, among girls, lower self-esteem. The relationship between sensation seeking, reckless…

  5. Development of an advanced, continuous mild gasification process for the production of co-products: Topical report

    Energy Technology Data Exchange (ETDEWEB)

    Cha, C.Y.; Merriam, N.W.; Jha, M.C.; Breault, R.W.

    1988-06-01

    Research on mild gasification is discussed. The report is divided into three sections: literature survey of mild gasification processes; literature survey of char, condensibles, and gas upgrading and utilization methods; and industrial market assessment of products of mild gasification. Recommendations are included in each section. (CBS) 248 refs., 58 figs., 62 tabs.

  6. Polar DuaLs of Convex Bodies

    Science.gov (United States)

    1990-01-01

    to Convex Bodies, Geometriae Dedicata 2" (1973) 225-248. 10. H. Guggenheimer, "The Analytic Geometry of the Unsymmetric Minkowski Plane," Lecture...Mathematics, Vol. 58, No. 2, 1975. 19. E. Lutwak, "On Cross-Sectional Measures of Polar Reciprocal Convex Bodies," Geometriae Dedicata 5, (1976) 79-80

  7. QTL Information Table: 228 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available i 63 B C547 C2340 pha Xing, Z., Tan, F., Hua, P., Sun, L., Xu, G., and Zhang, Q. (2002). Characterization of the main effects..., epistatic effects and their environmental interactions of QTLs on the genetic basis of yield traits in rice. Theor Appl Genet 105, 248-257. ...

  8. Parent-Endorsed Sex Differences in Toddlers with and without ASD: Utilizing the M-CHAT

    Science.gov (United States)

    Øien, Roald A.; Hart, Logan; Schjølberg, Synnve; Wall, Carla A.; Kim, Elizabeth S.; Nordahl-Hansen, Anders; Eisemann, Martin R.; Chawarska, Katarzyna; Volkmar, Fred R.; Shic, Frederick

    2017-01-01

    Sex differences in typical development can provide context for understanding ASD. Baron-Cohen ("Trends Cogn Sci" 6(6):248-254, 2002) suggested ASD could be considered an extreme expression of normal male, compared to female, phenotypic profiles. In this paper, sex-specific M-CHAT scores from N = 53,728 18-month-old toddlers, including n…

  9. Dicty_cDB: Contig-U15078-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available e RP23-248L5 from 14, comple... 38 0.46 7 ( AC116960 ) Dictyostelium discoideum chromosome 2 map complem... ...34 0.61 9 ( AC150299 ) Carollia perspicillata clone 309L9, complete sequ... 40 0.68 3 ( AC023765 ) Homo sapi

  10. The Life-of-Type Inventory Decision for Diminishing Manufacturing Sources Items: A Sensitivity Study.

    Science.gov (United States)

    1982-09-01

    34safety level" of stock for these items. The VSL formula used by DESC is based upon "Model IV" of Presutti and Trepp (the reader is referred to 33:248...Richard C. Trepp . "More Ado About Economic Order Quantities (EOQ)," Naval Research Logistics Quarterly, Vol. 17, No. 2 (June 1970), pp. 243-251. 34

  11. Defense Manpower Policy: Presentations from the 1976 Rand Conference on Defense Manpower

    Science.gov (United States)

    1978-12-01

    Retention. Related Variables, U.S.N. Personnel Research Activity, Report No, 248, December 1964. La Rocco, James M., Eric Gunderson, and William M. Pugh...military status sepa- U 304 Thomaa rate from, but not equal to, that of men. This move was motivated by the findings of a study that a million and a half

  12. 77 FR 59829 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

    Science.gov (United States)

    2012-10-01

    ... 1999-2000 397 ..... ..... BMW 3 Series....... 1998 462 ..... ..... BMW 3 Series....... 1999 379 ..... ..... BMW 3 Series....... 2000 356 ..... ..... BMW 3 Series....... 2001 379 ..... ..... BMW 3 Series....... 1995-1997 248 ..... ..... BMW 3 Series....... 2003-2004 487 ..... ..... BMW 318i, 318iA.......

  13. 75 FR 57396 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

    Science.gov (United States)

    2010-09-21

    ...) SB8 1999-2000 397 ...... ...... Bimota (MC) SB6 1994-1999 523 ...... ...... BMW 316 1986 25 ...... ...... BMW 3 Series 1998 462 ...... ...... BMW 3 Series 1999 379 ...... ...... BMW 3 Series 2000 356 ...... ...... BMW 3 Series 2001 379 ...... ...... BMW 3 Series 1995-1997 248 ...... ...... BMW 3 Series...

  14. Long-term influences of body-weight changes, independent of the attained weight, on risk of impaired glucose tolerance and Type 2 diabetes

    DEFF Research Database (Denmark)

    Black, E; Holst, C; Astrup, A

    2005-01-01

    = 248) and one of randomly selected control (n = 320) men, weighed at average ages of 20, 33, 44 and 51 years, respectively. RESULTS: For any given BMI, the risk of IGT was higher the greater the weight gain since age 20 (odds ratio of 1.10 per unit kg/m2 of BMI gain, confidence interval 1.03-1.17, P...

  15. Differential Effects of Women's Child Sexual Abuse and Subsequent Sexual Revictimization.

    Science.gov (United States)

    Wyatt, Gail Elizabeth; And Others

    1992-01-01

    Examined differential effects of sexual revictimization in community sample of 248 African-American and white women, ages 18 to 36. Findings suggest that unintended pregnancies and abortions were significantly associated with sexual revictimization. Women who reported more than one incident in both childhood and adulthood were also likely to have…

  16. An Exploratory Survey of Transition Teaching Practices: Results from a National Sample

    Science.gov (United States)

    Pham, Yen K.

    2013-01-01

    This study used multilevel modeling to examine the extent to which secondary special educators promoted nonacademic behaviors that were positively linked to postschool outcomes for students with disabilities, including self-advocacy, goal setting and attainment, disability awareness, employment, and utilization of supports. Respondents were 248

  17. Refractive microlenses produced by excimer laser machining of poly(methyl methacrylate)

    DEFF Research Database (Denmark)

    Jensen, Martin Frøhling; Krühne, Ulrich; H., L.;

    2005-01-01

    A method has been developed whereby refractive microlenses can be produced in poly (methyl methacrylate) by excimer laser irradiation at λ = 248 nm. The lenses are formed by a combined photochemical and thermal process. The lenses are formed as depressions in the substrate material (negative foca...

  18. A compact refractometric sensor based on grated silicon photonic wires

    NARCIS (Netherlands)

    Kauppinen, L.J.; Hoekstra, H.J.W.M.; Ridder, de R.M.

    2009-01-01

    Grated silicon photonic wires for refractometric applications have been fabricated using a 248-nm deep UV lithography. It is shown experimentally, that a device with length of only 180m has an index sensitivity of $10^{-6}$ assuming a detector power resolution of 1%. It is also demonstrated that the

  19. Clinician’s perceptions of and emotional responses to online infidelity

    NARCIS (Netherlands)

    Dijkstra, Pieternel; de Zeeuw, Heleen; Barelds, Dick P.H.; Buunk, Abraham P.

    2015-01-01

    Aim of the present study was to examine the degree to which mental health workers perceive twelve online partner behaviors as different types of infidelity and to examine the degree to which these behaviors evoke two types of jealousy, that is, fait accompli and anxious jealousy among mental. 248 he

  20. AcEST: BP916703 [AcEST

    Lifescience Database Archive (English)

    Full Text Available .. 31 2.8 sp|P06300|PDYN_RAT Beta-neoendorphin-dynorphin OS=Rattus norvegi... 30 3.5 sp|P18146|EGR1_HUMAN Ea...27 >sp|P06300|PDYN_RAT Beta-neoendorphin-dynorphin OS=Rattus norvegicus GN=Pdyn PE=1 SV=2 Length = 248 Score

  1. Acetylcholinesterase Inhibitors on the Spinal Cord.

    Science.gov (United States)

    1991-11-22

    in vitro. J. Pharmacol. Exp. Ther. 248, 1048-1053. 19. Cheney, P.D., Kasser , R.J., and Holsapple, J. (1987) Effects of DFP on unit activity in rat... Kasser , R.J., and Cheney, P.D. (1987) DFP action on rat superior colliculus: localization and role of cholinergic receptors. Neurotoxicology 8, 607

  2. Low-Noise Operation of All-Fiber Femtosecond Cherenkov Laser

    DEFF Research Database (Denmark)

    Liu, Xiaomin; Villanueva Ibáñez, Guillermo Eduardo; Lægsgaard, Jesper;

    2013-01-01

    We investigate the noise properties of a femtosecond all-fiber Cherenkov radiation source with emission wavelength around 600 nm, based on an Yb-fiber laser and a highly-nonlinear photonic crystal fiber. A relative intensity noise as low as - 103 dBc/Hz, corresponding to 2.48 % pulse-to-pulse flu...

  3. The role of MRI in the diagnosis of acute radiation reaction in breast cancer patient

    Science.gov (United States)

    Startseva, Zh A.; Musabaeva, L. I.; Usova, AV; Frolova, I. G.; Simonov, K. A.; Velikaya, V. V.

    2016-02-01

    A clinical case with acute radiation reaction of the left breast after organ-preserving surgery with 10 Gy IORT (24.8 Gy) conventional radiation therapy has been presented. Comprehensive MRI examination showed signs of radiation- induced damage to skin, soft tissues and vessels of the residual breast.

  4. Synergistic Effects of Exposure of Surfaces of Ionic Crystals to Radiation and Water

    Energy Technology Data Exchange (ETDEWEB)

    Dickinson, J T.; Nwe, Khin H.; Hess, Wayne P.; Langford, S C.

    2003-03-15

    We present studies of the consequences of simultaneous exposure of inorganic single crystals to radiation and water. The first case consists of a biomineral, CaHPO4-2H2O (brushite), which is a wide band gap, hydrated inorganic single crystal. We examine the laser-induced ion and neutral emissions accompanying 248 nm excimer laser radiation.

  5. Asian archaeology. Comment on "Agriculture facilitated permanent human occupation of the Tibetan Plateau after 3600 B.P. ".

    Science.gov (United States)

    Guedes, Jade d'Alpoim; Bocinsky, R Kyle; Butler, Ethan E

    2015-05-22

    Chen et al. (Reports, 16 January 2015, p. 248) argued that early Tibetan agriculturalists pushed the limits of farming up to 4000 meters above sea level. We contend that this argument is incompatible with the growing requirements of barley. It is necessary to clearly define past crop niches to create better models for the complex history of the occupation of the plateau.

  6. Students’ anticipated situational engagement : the roles of teacher behaviour, personal engagement, and gender

    NARCIS (Netherlands)

    Thijs, J.T.; Verkuyten, M.J.A.M.

    2009-01-01

    Among 9th-grade students (248 girls, 255 boys) from a large multiethnic school, the authors examined 2 aspects of anticipated situational engagement in relation to 3 types of hypothetical teacher behavior: authoritarian, authoritative, permissive. Furthermore, the authors investigated the moderating

  7. AcEST: DK960090 [AcEST

    Lifescience Database Archive (English)

    Full Text Available marctos ornatus GN=MT-CYB... 32 1.4 sp|O21366|CYB_NEOFO Cytochrome b OS=Neomys fodiens GN=MT-CYB PE=... 31 2...48 >sp|O21366|CYB_NEOFO Cytochrome b OS=Neomys fodiens GN=MT-CYB PE=3 SV=2 Length = 379 Score = 30.8 bits (6

  8. EST Table: BP120323 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available inding)|GO:0015074(DNA integration) 10/09/28 46 %/248 aa ref|XP_002431503.1| enzymatic polyprotein; Endonucl...ease; Reverse transcriptase, putative [Pediculus humanus corporis] gb|EEB18765.1| enzymatic polyprotein; End

  9. High and Mighty: Implicit Associations between Space and Social Status

    Science.gov (United States)

    2011-10-10

    e.g., Piaget , 1927/1969; Tversky et al., 1991). To date, dozens of experiments across a wide range of disciplines, from psychology to anthropol- ogy...The Psychology of Learn- ing and Motivation, ed. B. H. Ross (Burlington: Academic Press), 217–248. Piaget , J. (1927/1969). The Child’s Con- ception of

  10. Comparison of traditional field retting and Phlebia radiata Cel 26 retting of hemp fibres for fibre-reinforced composites

    DEFF Research Database (Denmark)

    Liu, Ming; Ale, Marcel Tutor; Kołaczkowski, Bartłomiej

    2017-01-01

    Classical field retting and controlled fungal retting of hemp using Phlebia radiata Cel 26 (a mutant with low cellulose degrading ability) were compared with pure pectinase treatment with regard to mechanical properties of the produced fibre/epoxy composites. For field retting a classification...... was obtained using P. radiata Cel 26 compared to 248 MPa with field retting....

  11. Adolescents' Perceptions of Family Connectedness, Intrinsic Religiosity, and Depressed Mood

    Science.gov (United States)

    Houltberg, Benjamin J.; Henry, Carolyn S.; Merten, Michael J.; Robinson, Linda C.

    2011-01-01

    Using a sample of 248 ninth and tenth grade students at public high schools, we examined adolescents' perceptions of family connectedness, intrinsic religiosity, and adolescents' gender in relation to depressed mood and whether intrinsic religiosity and gender moderated the association of aspects of family connectedness to adolescent depressed…

  12. 自由电子激光器

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    TN248.6 2000053181Smith-Purcell型自由电子激光的辐射=Radiation in Smith-Purcell efffect FEL[刊,中]/熊平凡(孝感师范高等专科学校.湖北,孝感(432100))//激光与光电子学进展.—1999,(12).—21-24

  13. Thinking about Applications: Effects on Mental Models and Creative Problem-Solving

    Science.gov (United States)

    Barrett, Jamie D.; Peterson, David R.; Hester, Kimberly S.; Robledo, Issac C.; Day, Eric A.; Hougen, Dean P.; Mumford, Michael D.

    2013-01-01

    Many techniques have been used to train creative problem-solving skills. Although the available techniques have often proven to be effective, creative training often discounts the value of thinking about applications. In this study, 248 undergraduates were asked to develop advertising campaigns for a new high-energy soft drink. Solutions to this…

  14. Does Self-Image Matter? Client's Self-Image, Behaviour and Evaluation of a Career Counselling Session: An Exploratory Study

    Science.gov (United States)

    Schedin, Gunnar; Armelius, Kerstin

    2008-01-01

    This exploratory study addresses differences in self-image as a client characteristic in career counselling by using the Structural Analysis of Social Behaviour (Benjamin, L., "Journal of Consulting and Clinical Psychology," 64(6), 1203-1212, 1996; Benjamin, L., "Journal of Personality Assessment," 66(2), 248-266, 1996) and an adaptation…

  15. Protection against Acute Lethal Viral Infections with the Native Steroid Dehydroepiandrosterone (DHEA)

    Science.gov (United States)

    1988-01-01

    Etiocholanolones in Diabetes (db), viable yellow (AY), and normal mice. Endocrinologia 117:2279-2283. Coleman DL, Leiter EH, Applezweig N (1984b...Therapeutic effects of dchydroepiandrosterone metab- olites in diabetes mutant mice (C57BL/KsJ dbldb). Endocrinologia 115:238-248. Coleman DL, Leiter EA

  16. Use of Complementary and Alternative Medicine (CAM) Treatments by Parents of Children with Autism Spectrum Disorders

    Science.gov (United States)

    Christon, Lillian M.; Mackintosh, Virginia H.; Myers, Barbara J.

    2010-01-01

    Parents of children with autism spectrum disorders (ASDs) may elect to use complementary and alternative medicine (CAM) treatments with their children in place of, or in addition to, conventional treatments. CAM treatments are controversial and understudied and, for most, the efficacy has not been established. The current study (n = 248) examined…

  17. Sublethal Ciprofloxacin Treatment Leads to Rapid Development of High-Level Ciprofloxacin Resistance during Long-Term Experimental Evolution of Pseudomonas aeruginosa

    DEFF Research Database (Denmark)

    Jørgensen, Karin Meinike; Wassermann, Tina; Jensen, Peter Østrup

    2013-01-01

    lineages after 240 generations. The genetic basis of resistance was mutations in gyrA (C248T and G259T) and gyrB (C1397A). Cross-resistance to beta-lactam antibiotics was observed in the bacterial populations that evolved during exposure to sublethal concentrations of ciprofloxacin. Our study shows...

  18. Domain Modeling: NP_005402.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_005402.3 chr10 High resolution crystal structure of an active recombinant fragment of human lung surfacta...nt protein D with maltose c1pwbc_ chr10/NP_005402.3/NP_005402.3_holo_102-248.pdb bl

  19. Domain Modeling: NP_008857.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_008857.2 chr10 High resolution crystal structure of an active recombinant fragment of human lung surfacta...nt protein D with maltose c1pwbc_ chr10/NP_008857.2/NP_008857.2_holo_102-248.pdb bl

  20. Combined effects of prenatal exposures to environmental chemicals on birth weight

    DEFF Research Database (Denmark)

    Govarts, Eva; Remy, Sylvie; Bruckers, Liesbeth

    2016-01-01

    Prenatal chemical exposure has been frequently associated with reduced fetal growth by single pollutant regression models although inconsistent results have been obtained. Our study estimated the effects of exposure to single pollutants and mixtures on birth weight in 248 mother-child pairs. Arse...

  1. Ballistics of the 30-06 Rifle Cartridge

    Science.gov (United States)

    2012-11-30

    www.hodgdon.com/PDF/Youth%20Loads.pdf. 14. Endris, Graham. DETAIL SPECIFICATION CARTRIDGE,.300 WINCHESTER MAGNUM MATCH, MK 248 MOD 1 DODIC AB43...Jason T. Gomez and Arun Shukla November 2001, pp. 965-979. 10, November 2001, International Journal of Impact Engineering, Vol. 25, pp. 965-979

  2. Book Review: F. KONDYLI - V. ANDRIOPOULOU - E. PANOU - M. B. CUNNIGHAM (edd., Sylvester Syropoulos on Politics and Culture in the Fifteenth Century Mediterranean. Themes and Problems in the Memoirs, Section IV, Αshgate 2014

    Directory of Open Access Journals (Sweden)

    Photeine PERRA

    2016-01-01

    Full Text Available Book Review: Fotini KONDYLI - Vera ANDRIOPOULOU - Eirini PANOU - Mary B. CUNNIGHAM (edd., Sylvester Syropoulos on Politics and Culture in the Fifteenth Century Mediterranean. Themes and Problems in the Memoirs, Section IV, [Birmingham Byzantine and Ottoman Studies, volume 16], Ashgate, 2014, pp. 248, ISBN: 978-1-4094-3966-0

  3. Book Review: F. KONDYLI - V. ANDRIOPOULOU - E. PANOU - M. B. CUNNIGHAM (edd.), Sylvester Syropoulos on Politics and Culture in the Fifteenth Century Mediterranean. Themes and Problems in the Memoirs, Section IV, Αshgate 2014

    OpenAIRE

    PERRA, Photeine

    2016-01-01

    Book Review: Fotini KONDYLI - Vera ANDRIOPOULOU - Eirini PANOU - Mary B. CUNNIGHAM (edd.), Sylvester Syropoulos on Politics and Culture in the Fifteenth Century Mediterranean. Themes and Problems in the Memoirs, Section IV, [Birmingham Byzantine and Ottoman Studies, volume 16], Ashgate, 2014, pp. 248, ISBN: 978-1-4094-3966-0

  4. 40 CFR 73.10 - Initial allocations for phase I and phase II.

    Science.gov (United States)

    2010-07-01

    ... Y5BR 9162 248 Y6BR 24108 652 Y7BR 20915 565 Illinois Baldwin 1 46052 1245 2 48695 1316 3 46644 1261... 4158 112 Mississippi Jack Watson 4 17439 471 5 35734 966 Missouri Asbury 1 15764 426 James River 5...

  5. Isolation and genetic characterization of Toxoplasma gondii from the gray wolf Canis lupus

    Science.gov (United States)

    Little is known of the genetic diversity of Toxoplasma gondii circulating in wildlife. In the present study feral gray wolf (Canis lupus) from Minnesota were examined for T. gondii infection. Antibodies to T. gondii were detected in 130 (52.4%) of 248 wolves tested by the modified agglutination test...

  6. Channel Shoaling with Deepening of Houma Navigation Channel at Cat Island Pass, Louisiana

    Science.gov (United States)

    2011-01-01

    islands must be maintained as morphologic features to sustain the low-energy, lower- salinity estuarine characteristics of Timbalier Bay and the...248p. Mayor-Mora, R.; Mortensen, P., and Fredsoe, J., 1976. Sedimentation studies on the Niger River delta. Proceedings, 15th Coastal Engineering

  7. Rethinking US Security Policy for the 1980s. Proceedings of the Annual National Security Affairs Conference (7th) held 21-23 July 1980, Fort McNair, Washington, DC.

    Science.gov (United States)

    1980-01-01

    they revealed American, French, Moroccan , and implicit Saudi (and perhaps Iranian) involvement in the effort to bolster the Mobutu regime in Zaire...de desarmement," Politique Etrangere 44 (1979): 213-248. 8. For recent commentary on European monetary policy, see Benjamin J. Cohen, "Le SME . le

  8. Red Blood Cells Accelerate the Onset of Clot Formation in Polytrauma and Hemorrhagic Shock

    Science.gov (United States)

    2010-11-01

    was produced as described in our previous work.7 A well- validated lethal triad ( acidosis , coagulopathy, and hypother- Submitted for publication...outcome in 466 massively transfused civilian trauma patients. Ann Surg. 2008;248:447–458. 3. Sperry JL, Ochoa JB, Gunn SR, et al; Inflammation the Host

  9. Computation in Networks of Passively Mobile Finite-State Sensors

    Science.gov (United States)

    2004-02-23

    in the case of conjugating automata. The Chemical Abstract Machine of Berry and Boudol [2] is an abstract machine designed to model a situation in...2003. [2] G. Berry and G. Boudol. The Chemical Abstract Machine. Theoretical Computer Science, 96:217–248, 1992. [3] D. Brand and P. Zafiropulo. On

  10. The influence of criminal offending on union formation and union dissolution for disadvantaged individuals

    NARCIS (Netherlands)

    Zoutewelle-Terovan, M.; van der Geest, V.; Liefbroer, A.C.; Bijleveld, C.

    2016-01-01

    Using a sample of 248 males and females from The Netherlands, we study the effect of criminal offending on union formation and union dissolution. Criminal and relational careers of high-risk respondents are analyzed using a long observation period (age 12 to age 36). Findings for men support the hyp

  11. 75 FR 41575 - Notice of Intent To Prepare an Environmental Impact Statement for a Long-Term Landscape...

    Science.gov (United States)

    2010-07-16

    ... Act ( http://www.vallescaldera.gov/about/trust/docs/PL%20106-248.pdf ), the Management Principles.... Management of the VCNP is considered an experiment in public land management. The purposes and goals from... Management Plan To Restore and Manage the Forest, Grassland, and Riparian Ecosystems of the Valles...

  12. Cumulative Reports and Publications through December 31, 1992

    Science.gov (United States)

    1993-04-01

    tip body and time hysteresis camping. ICASE Report No. 89-22, April 18, 1989. 24 pages. Matematica Aplicada e Computacional , Vol. 8, No. 2, pp. 101-118...distributed parameter systems. ICASE Report No. 85-58, November 22, 1985, 102 pages. Mathematica Applicada e Computacional , Vol. 5, No. 3, 1987, pp. 203-248

  13. Spectral and spatial structure of extreme ultraviolet radiation in laser plasma-wall interactions

    NARCIS (Netherlands)

    Kuznetsov, A. S.; Stuik, R.; F. Bijkerk,; Shevelko, A. P.

    2012-01-01

    Intense extreme ultraviolet (XUV) radiation was observed during the interaction of low-temperature laser plasmas and wall materials. Laser plasmas with electron temperature T-e similar to 40 eV were created on massive solid targets (CF2 and Al) by an excimer KrF laser (248 nm/0.5 J/13 ns/1 Hz). The

  14. AcEST: DK959921 [AcEST

    Lifescience Database Archive (English)

    Full Text Available DTR Putative uncharacterized protein OS=Medic... 248 2e-64 tr|B5LWQ7|B5LWQ7_ZIZJJ Ubiquitin extensive-like p...B5LWQ7|B5LWQ7_ZIZJJ Ubiquitin extensive-like protein OS=Ziziphus jujuba GN=UBQ PE=2 SV=1 Length = 156 Score

  15. Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat

    DEFF Research Database (Denmark)

    Maddahi, Aida; Chen, Qingwen; Edvinsson, Lars

    2009-01-01

    of metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1). RESULTS: Here, we found an infarct volume of 24.8 +/- 2% and a reduced neurological function after two hours of middle cerebral artery occlusion (MCAO), followed by 48 hours of recirculation in rat. Immunocytochemistry and confocal...

  16. Preliminary Assessment/Site Investigation: Tooele Army Depot, Utah. Volume 1. North Area and Facilities at Hill Air Force Base. Appendixes

    Science.gov (United States)

    1988-12-01

    2,4 ,6-TRINITROBENZALDENYDE ATNT kLPHA-TRINITROTOLUENE (OBSOLETE; USE 246TNT) ATZ ATRAZ1NE AYLETH ALLYL ETHER AZACN AZACYLONONANE B BORON BA BARIUM ... STYPHNATE PCB016 PCB 1016 PCB221 PCB 1221 PCB232 PCB 1232 PCB242 PCB 1242 PCB248 PCB 1248 PCB254 PCB 1254 PCB260 PCB 1260 PCB262 PCB 1262 PCP

  17. AcEST: BP912749 [AcEST

    Lifescience Database Archive (English)

    Full Text Available utative uncharacterized protein OS=Medic... 164 2e-39 tr|Q8RXA7|Q8RXA7_ARATH Stomatal...CVEYSSLDRGIITGSTDG 247 Query: 9 TVK 1 ++ Sbjct: 248 LLR 250 >tr|Q8RXA7|Q8RXA7_ARATH Stomatal

  18. List of Participating Institutions: Associated Schools Project in Education for International Co-operation and Peace = Liste des establissements participants: Systeme des ecoles associees appliquant un programme d'education pour la cooperation internationale et la paix = Lista de Instituciones Participantes: Plan de Escuelas Asociadas en la Educacion para la Cooperacion Internacional y la Paz.

    Science.gov (United States)

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    A list of participating institutions at the Associated Schools Project in Education for International Co-Operation and Peace, December 31, 1985 is presented. A total of 1,970 institutions in 94 countries participated, including 47 nursery schools, 556 primary schools, 1,123 secondary schools, and 248 teacher training institutions. Addresses of…

  19. 75 FR 18091 - Final Flood Elevation Determinations

    Science.gov (United States)

    2010-04-09

    ....: FEMA-B-1043 Bayou La Nana Approximately 1,246 feet +248 Unincorporated Areas of upstream of the... La Nana Approximately 921 feet +317 Unincorporated Areas of upstream of Loop 224. Nacogdoches County... Nacogdoches County, City confluence with Bayou La of Nacogdoches. Nana. Approximately 727 feet +284...

  20. Quantification of Physical Activity During Basic Combat Training and Associated Injuries

    Science.gov (United States)

    2014-03-31

    Campbell CC: An epidemiologic study of the benefits and risks of running. JAMA 1982, 248:3118-3121. 54. Koplan JP, Rothenberg RB, Jones EL: The natural... YOGA . 1v. High, or 70-95% effort: Jogging/running@ 12- 6min/mile or combatives. v. Maximum, or 96-100% effort: All-out effort, i.e. a sprint Work

  1. Stable periodicity and negative circuits in differential systems.

    Science.gov (United States)

    Richard, Adrien; Comet, Jean-Paul

    2011-09-01

    We provide a counter-example to a conjecture of René Thomas on the relationship between negative feedback circuits and stable periodicity in ordinary differential equation systems (Kaufman et al. in J Theor Biol 248:675-685, 2007). We also prove a weak version of this conjecture by using a theorem of Snoussi.

  2. Language studies in higher education in the Netherlands

    NARCIS (Netherlands)

    Zwarts, Frans; Silkens, B.

    1995-01-01

    Dutch is one of the two official languages of the Netherlands. It is the mother tongue of 15 million Dutchmen and 5,5 million Belgians. The second official language is Frisian, which is spoken by the 500,000 inhabitants of Friesland - a province of the Netherlands, 1,248 square miles in area, in the

  3. Increasing Fleet Readiness Through Improved Distance Support

    Science.gov (United States)

    2013-03-01

    20 III. MILESTONES AND DELI VERABLE...for each of the tasks required to complete all deli verables. 22 248 ID ’’"""" 0 llist<n:e St4lPOrt Clspta’le Project lritiate Project 17days

  4. Studies on the chemistry of element 104 with the centrifuge system SISAK-3

    Energy Technology Data Exchange (ETDEWEB)

    Eberhardt, K.; Kratz, J.V.; Mendel, M.; Naehler, A.; Trautmann, N.; Wiehl, N. [Mainz Univ. (Germany); Alstadt, J.; Omtvedt, J.P. [Oslo Univ. (Norway); Malmbeck, R.; Skarnemark, G.; Wierczinski, B. [Chalmers Univ. of Technology, Goeteborg (Sweden); Eichler, B.; Gaeggeler, H.W.; Jost, D.T.; Tuerler, A. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-09-01

    The centrifuge system SISAK-3 combined with a detector for the measurement of {alpha}-particles and spontaneous fission (SF) fragments in a flowing organic liquid has been applied to study the chemical behaviour of element 104 produced in the reaction {sup 248}Cm({sup 18}O,5n){sup 261}104. (author) 2 figs., 2 refs.

  5. AcEST: DK949606 [AcEST

    Lifescience Database Archive (English)

    Full Text Available . 68 4e-11 sp|Q9BT17|MTG1_HUMAN Mitochondrial GTPase 1 OS=Homo sapiens GN=M... 68 5e-11 sp|Q4PS77|MTG1_BOVIN... + Sbjct: 230 LVGEETMADYLLYTLNKHQ 248 >sp|Q4PS77|MTG1_BOVIN Mitochondrial GTPase

  6. Longitudinal Study on Reciprocity between Personality Traits and Parenting Stress

    Science.gov (United States)

    Rantanen, Johanna; Tillemann, Kati; Metsäpelto, Riitta-Leena; Kokko, Katja; Pulkkinen, Lea

    2015-01-01

    Reciprocal associations between the Big Five personality traits and parenting stress--including both parents' feelings of their distress and perception of their incompetence as parents--were studied with 248 participants (49% of which were males). Longitudinal data, collected at ages 33/36, 42 and 50 years, were used. Cross-lagged path analysis…

  7. The effect of oxfendazole treatment on muscle pathology in pigs infected with Taenia solium cysticercosis

    DEFF Research Database (Denmark)

    Iburg, Tine Moesgaard; Karlsson, Madeleine; Spång, Frederic

    2012-01-01

    The aim of the present study was to test histopathologically the hypothesis that the time for clearing Taenia solium cysts in muscle tissue of pigs following treatment with oxfendazole is cyst density dependant. A total of 248 cyst lesions in the masseter muscle of 28 naturally infected pigs were...

  8. Effects of Self-Perceptions on Self-Learning among Teacher Education Students

    Science.gov (United States)

    Liu, Shih-Hsiung

    2015-01-01

    This study evaluates the multivariate hypothesized model that predicts the significance of, and relationships among, various self-perception factors for being a qualified teacher and their direct and mediated effects on self-learning activities among teacher education students. A total of 248 teacher education students enrolled at an education…

  9. Database for TA (PL) and UTC (PL)

    Science.gov (United States)

    2008-12-01

    Scale Algorithms,” Metrologia , 28, 57-63. [4] C. Thomas, P. Wolf, and P. Tavella, 1994, “Time scales,” BIPM Monographie 94/1. [5] ITU, 1997...Azoubib, J. Nawrocki, and W. Lewandowski, 2003, “Independent atomic time scale in Poland – organization and results,” Metrologia , 40, S245-S248

  10. Urban Principal Leadership Skill Proficiency and Student Achievement

    Science.gov (United States)

    Winn, Pam; Erwin, Sue; Gentry, Jim; Cauble, Mary

    2009-01-01

    Because of the importance of developing highly skilled urban school leaders, statewide assessments of 248 urban Texas public school administrators were analyzed to determine principal confidence levels in leadership skill domains identified by the National Policy Board of Educational Administration (NPBEA). Important findings indicate differences…

  11. A comparative study of via drilling and scribing on PEN and PET substrates for flexible electronic applications using excimer and Nd:YAG laser sources

    NARCIS (Netherlands)

    Mandamparambil, R.; Fledderus, H.; Brand, J. van den; Saalmink, M.; Kusters, R.; Podprocky, T.; Steenberge, G. van; Baets, J. de; Dietzel, A.H.

    2009-01-01

    A study on via drilling and channel scribing on PEN and PET substrates for flexible electronic application is discussed in this paper. For the experiments, both KIF excimer laser (248 nm) and frequency tripled Nd:YAG (355 nm) laser are used. Different measurement techniques like optical microscopy,

  12. Innovation in Business Organizations: Adoption of Japanese Management Principles and Communications Technologies.

    Science.gov (United States)

    Edwards, Renee; And Others

    A survey was completed by 248 North Carolinian companies in a study conducted to determine the extent to which businesses have responded to recent theories on Japanese management principles and communication technologies. The five areas of the survey focused on (1) characteristics of the respondent and organization, (2) communication and decision…

  13. A Canonical Correlation Analysis of the Influence of Social Comparison, Gender, and Grade Level on the Multidimensional Self-Concepts of Gifted Adolescents

    Science.gov (United States)

    Rinn, Anne N.; Jamieson, Kelly M.; Gross, Candace M.; McQueen, Kand S.

    2009-01-01

    This study examines the effects of social comparison, gender, and grade level on gifted adolescents' multidimensional self-concept. Participants include 248 gifted adolescents who had completed the sixth through tenth grade during the previous academic year. Multidimensional self-concept was measured using the Self Description Questionnaire II…

  14. Environmental Assessment for Selected Regions in the Mediterranean Sea

    Science.gov (United States)

    1992-01-01

    shallow sill and travel eastward along the interface between the dissimilar water masses at a speed of 3 to 4 kt. Temperature differences on the order of...the eastern Mediterranean. OceanoL Acta 9(3): 239-248. Arevalo, L. and T. Garcia (1982). Corrientes de la Costa de Malaga, metodos y resultados. Inf

  15. 17 CFR Appendix to Subpart B of... - Model Forms

    Science.gov (United States)

    2010-04-01

    ...) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing Pt. 248, Subpt. B, App. Appendix... such as “the group of companies.” 4. Substituting other types of affiliates covered by the notice for... Initial Opt Out Notice (Joint Notice) A-3—Model Form for Renewal Notice (Single-Affiliate Notice)...

  16. Bibliography

    NARCIS (Netherlands)

    NN,

    1956-01-01

    Adamson, R.S.: The South African species of Aizoaceae. II. Tetragonia. (J. S. Afr. Bot. 21, 1955, 109-154). Key. Akiyama, S.: Carices of the Far Eastern region. Sapporo. 1955. 1-257. t. 1-248. Magnificent monograph; keys & descr. in Jap.; syn. in Engl.

  17. Effects of Nonadecafluorodecanoic Acid on Tissue Fatty Acids of the Rat.

    Science.gov (United States)

    1982-01-01

    solvents ( Lehninger , 1977). Fatty acids are incorporated in complex lipids such as acyl- glycerols, phosphoglycerides, and sphingolipids and as such serve...sition and Osmotic Fragility of Erythrocytes of Hamsters Induced by Heat Exposure, Biochim. Biophys. Acta, 248:300-305, 1971. Lehninger , A. L

  18. Complete genome sequence of Streptomyces sp. strain CFMR 7, a natural rubber degrading actinomycete isolated from Penang, Malaysia.

    Science.gov (United States)

    Nanthini, Jayaram; Chia, Kim-Hou; Thottathil, Gincy P; Taylor, Todd D; Kondo, Shinji; Najimudin, Nazalan; Baybayan, Primo; Singh, Siddharth; Sudesh, Kumar

    2015-11-20

    Streptomyces sp. strain CFMR 7, which naturally degrades rubber, was isolated from a rubber plantation. Whole genome sequencing and assembly resulted in 2 contigs with total genome size of 8.248 Mb. Two latex clearing protein (lcp) genes which are responsible for rubber degrading activities were identified.

  19. Effects of Chemistry and Processing on the Fracture Related Properties of P/M Alloy CT91.

    Science.gov (United States)

    1985-08-01

    p. 245. 141. R.O. Ritchie, mEnvironmentally-Sensitive Fracture of Engineering Materials", Z.A. Foroylis, Ed, TMS-AIME, 1978. 142. J.F. Knott and A.C...AFWAL/ FIB , Personal Communication, 1979. 248. G. Chanani, Northrop Corporation, Personal Communication, 1979. 249. D. R. Holloway, "X-Ray Diffraction

  20. Attitudes of Medical School Faculty toward Gifts from the Pharmaceutical Industry.

    Science.gov (United States)

    Banks, James W., III; Mainous, Arch G., III

    1992-01-01

    A survey of 248 University of Kentucky medical school faculty investigated attitudes toward American Medical Association policy concerning gifts from the pharmaceutical industry. Faculty generally agreed with the guidelines but felt gifts did not influence prescribing behaviors. PhD faculty favored more prescriptive policy than did MD faculty.…

  1. Dicty_cDB: Contig-U09823-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available aattggatttcattattgaaaatccacaaattaaatt 772 Query: 773 ccatantgcatcatatgataatttactattaaaaatcattaaacttttagaaaat...gattt 832 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 773 ccatantgcatcatatgataatttac...ttattttgttgtgatactagaaatattaaattatttttcnaacaattgg 241 Query: 742 atttcattattgaaaatccacaaattaaattccatantgcatc...atatga 790 ||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 242 atttcatta...ttgaaaatccacaaattaaattccatantgcatcatatga 290 Score = 248 bits (125), Expect(2) = 0.0 Identities = 125/125 (1

  2. 76 FR 37979 - Cooperation in USDA Studies and Evaluations, and Full Use of Federal Funds in Nutrition...

    Science.gov (United States)

    2011-06-29

    ... Service 7 CFR Parts 210, 215, 220, 225, 226, 235, 246, and 248 RIN 0584-AE20 Cooperation in USDA Studies... studies and evaluations related to Programs authorized under the NSLA and the CNA. The HHFK Act also... Program; the Summer Food Service Program; the Child and Adult Care Food Program; State...

  3. Data of evolutionary structure change: 1I7KB-2ONUA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1I7KB-2ONUA 1I7K 2ONU B A PVGKRLQQELMTLMMSGDKGISAFPESDNLFKWVGTIHG.../entryChain> 2ONU A 2ONUA LEU CA 387 2ONU A 2ONU...248 THR CA 202 ALA CA 208 PHE CA 291 2ONU... A 2ONUA

  4. Ephedra equisetina Bunge 及び 近縁植物の種分類と多様性に関する研究

    OpenAIRE

    2015-01-01

    博士論文要旨Abstract 以下に掲載予定:The Journal of Japanese Botany 90(3) pp.235-248 2015. 植物研究雑誌編集委員会. 共著者:Hirokazu Ando, Masashi Matsumoto, Maksut Coşkun, Turgut Yilmaz, Nathalie Allain, Yohei Sasaki, Masayuki Mikage

  5. Molecular Targeted Therapies of Childhood Choroid Plexus Carcinoma

    Science.gov (United States)

    2013-10-01

    http://www.broad.mit.edu/igv/) ● Normalization of all data was then performed with SNP 6.0 files created for the third phase of the International... Mitosis (normalized enrichment score=2.61, FDR pɘ.001) o Spindle organization (normalized enrichment score=2.48, FDR pɘ.001) o Kinetochore

  6. EST Table: DC542114 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available DC542114 E_FL_dpe-_14I09_F_0 10/09/28 99 %/248 aa ref|NP_001040153.1| leucine zippe...|DwilGK10601-PA 10/08/28 35 %/272 aa H38K22.2a#CE33527#WBGene00010428#locus:dcn- 1#status:Confirmed#UniProt:

  7. 78 FR 39237 - Endangered and Threatened Wildlife and Plants; Designation of Critical Habitat for the Jaguar

    Science.gov (United States)

    2013-07-01

    ... hear any further appeal from those rulings (Arizona Cattle Growers' Assoc. v. Salazar, 606 F.3d 116... designating critical habitat (New Mexico Cattle Growers Ass'n v. FWS, 248 F.3d 1277 (10th Cir. May 11, 2001... 13563 (Regulatory Planning and Review), E.O. 13132 (Federalism), E.O. 12988 (Civil Justice Reform),...

  8. AcEST: DK949417 [AcEST

    Lifescience Database Archive (English)

    Full Text Available DO1_BRUSI 2-oxoglutarate dehydrogenase E1 component O... 248 1e-65 sp|A5VSQ0|ODO1_BRUO2...VTTPAN 630 E N QV NVTTPAN Sbjct: 803 ----------------EDNMQVANVTTPAN 816 >sp|A5VSQ0|ODO1_BRUO2 2-oxoglutarate

  9. Children and Advertising: A Bibliography. Working Draft.

    Science.gov (United States)

    Council of Better Business Bureaus, Inc., New York, NY.

    Some 248 books, articles, speeches, statements, and testimonies concerning the effects of television advertising on children are listed. Material that relates primarily to the effects of television program content is not included. The listing is alphabetical by author. All items were published between 1945 and 1975, with the majority published in…

  10. 75 FR 30425 - Endangered and Threatened Species Permit Applications

    Science.gov (United States)

    2010-06-01

    ... Chief, Endangered Species Division, Ecological Services, P.O. Box 1306, Room 6034, Albuquerque, NM 87103... Ave., SW., Room 6034, Albuquerque, NM. Please refer to the respective permit number for each... Species Division, P.O. Box 1306, Albuquerque, NM 87103; (505) 248-6920. SUPPLEMENTARY INFORMATION:...

  11. Dicty_cDB: Contig-U12608-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ore = 216 bits (109), Expect = 1e-56 Identities = 248/253 (98%) Strand = Plus / Plus Query: 4 aaaatgctncgagcatgncccagtnaaccnagctaaccn...||||||||||||||||||||||||||||| Sbjct: 4 aaaatgctncgagcatgncccagtnaaccnagctaaccnanaacctgaaagnattgnatt 63 Query...atgatggcgataaaaanananaggatcnaaaatcnactgcttcaaccccccnaggcna 183 ||||||||||||||||||...|||||||||||||||||||||||||||||||||||||||||| Sbjct: 124 ttatgatggcgataaaaanananaggatcnaaaatcnactgcttcaaccccccna...xpect = 2e-05 Identities = 83/105 (79%) Strand = Plus / Plus Query: 150 atcnaaaatcnactgcttcaaccccccnaggcnang

  12. Policy assessment and policy development for physical activity promotion: results of an exploratory intervention study in 15 European Nations

    NARCIS (Netherlands)

    Rütten, A.; Abu-Omar, K.; Gelius, P.; Dinan-Young, S.; Frändin, K.; Hopman-Rock, M.; Young, A.

    2012-01-01

    Background. Purpose of the study was to test a theoretical model to assess and develop policies for the promotion of physical activity among older people as part of an international intervention study. Methods 248 semi-standardized interviews with policy-makers were conducted in 15 European nations.

  13. Functioning of 7-Year-Old Children Born at 32 to 35 Weeks' Gestational Age

    NARCIS (Netherlands)

    Cserjesi, R.; Van Braeckel, K.N.J.A.; Butcher, P.R.; Kerstjens, J.M.; Reijneveld, S.A.; Bouma, A.; Geuze, R.H.; Bos, A.F.

    2012-01-01

    OBJECTIVE: To compare neuropsychological functions in moderately preterm (32-35 weeks' gestation) and full-term children at the age of 7 years and identify gender differences. METHODS: Community-based prospective cohort study of 248 moderately preterm children (138 boys) and 130 full-term children (

  14. 77 FR 73268 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2012-12-10

    ... service information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31... September 11, 2012. (3) For service information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424; fax: 011-44-1332- 245418,...

  15. 78 FR 20505 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2013-04-05

    ... information identified in this proposed AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31... information. (3) For service information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424; fax: 011-44-1332-249936 or...

  16. 78 FR 20507 - Airworthiness Directives; Rolls-Royce plc Turbofan Engines

    Science.gov (United States)

    2013-04-05

    ... information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby... related information. (3) For service information identified in this AD, contact Rolls-Royce plc, Corporate Communications, P.O. Box 31, Derby, England, DE248BJ; phone: 011-44-1332-242424; fax: 011-44-1332- 249936;...

  17. Efficient bragg grating fabrication in Ge-rich fibre by high-intensity femtosecond 264 mm irradation

    DEFF Research Database (Denmark)

    Slattery, S.A.; Nikogasyan, D.N.; Plougmann, Nikolai;

    2004-01-01

    Fibre Bragg gratings (FBGs) are usually fabricated by UV laser light (typically, 248 nm radiation from a KrF* excimer laser), which spectrally coincides with the absorption band of defects in germanosilicate fibre core [1, 2]. Recently, it was demonstrated that the use of highintensity femtosecon...

  18. The spatial thickness distribution of metal films produced by large area pulsed laser deposition

    DEFF Research Database (Denmark)

    Pryds, Nini; Schou, Jørgen; Linderoth, Søren

    2007-01-01

    Thin films of metals have been deposited in the large-area Pulsed Laser Deposition (PLD) Facility at Riso National Laboratory. Thin films of Ag and Ni were deposited with laser pulses from an excimer laser at 248 nm with a rectangular beam spot at a fluence of 10 J/cm(2) on glass substrates of 12...

  19. The Autism Diagnostic Experiences of French Parents

    Science.gov (United States)

    Chamak, Brigitte; Bonniau, Beatrice; Oudaya, Lila; Ehrenberg, Alain

    2011-01-01

    This survey focused on French parents' views of the diagnostic process relating to their child with autism. Data were collected on the age at diagnosis, the time taken to obtain a diagnosis and the difficulties encountered. Questionnaires filled in by the parents (n = 248) and in-depth interviews (n = 43) were analyzed in order to obtain…

  20. 20 CFR 25.100 - How is compensation for disability paid?

    Science.gov (United States)

    2010-04-01

    ... FEDERAL EMPLOYEES' COMPENSATION ACT COMPENSATION FOR DISABILITY AND DEATH OF NONCITIZEN FEDERAL EMPLOYEES... periods: (1) Arm lost: 280 weeks' compensation. (2) Leg lost: 248 weeks' compensation. (3) Hand lost: 212...-half of the compensation for the loss of the entire digit. (15) Amputated arm or leg: Compensation...

  1. Suicide in serial killers.

    Science.gov (United States)

    Lester, David; White, John

    2010-02-01

    In a sample of 248 killers of two victims in America from 1900 to 2005, obtained from an encyclopedia of serial killers by Newton (2006), those completing suicide did not differ in sex, race, or the motive for the killing from those who were arrested.

  2. Science and Technology Teachers' Opinions about Problems Faced While Teaching 8th Grade Science Unit "Force and Motion" and Suggestions for Solutions

    Science.gov (United States)

    Bozdogan, Aykut Emre; Uzoglu, Mustafa

    2015-01-01

    The aim of this study is to explore the problems encountered while teaching force and motion unit in 8th grade science and technology course from teachers' perspectives and offer solutions to eliminate these problems. The study was conducted with 248 science and technology teachers working in 7 regions in Turkey in 2012-2013 academic year.…

  3. AcEST: BP916995 [AcEST

    Lifescience Database Archive (English)

    Full Text Available Value sp|P41273|TNFL9_HUMAN Tumor necrosis factor ligand superfamily m... 33 0.85 sp|Q5RGE5|DCR1C_DANRE Protein artemis...LLHLSAGQRLGVHLHTEARARHAWQLTQGATVLGLFRVTPEIPAGL 248 >sp|Q5RGE5|DCR1C_DANRE Protein artemis OS=Danio rerio GN=

  4. HIV/AIDS Misconceptions among Latinos: Findings from a Population-Based Survey of California Adults

    Science.gov (United States)

    Ritieni, Assunta; Moskowitz, Joel; Tholandi, Maya

    2008-01-01

    Misconceptions about HIV/AIDS among Latino adults (N=454) in California were examined using data from a population-based telephone survey conducted in 2000. Common misconceptions concerning modes of HIV transmission included transmission via mosquito or animal bite (64.1%), public facilities (48.3%), or kissing someone on the cheek (24.8%). A…

  5. AcEST: DK946330 [AcEST

    Lifescience Database Archive (English)

    Full Text Available opu... 32 2.0 sp|P53929|YNK8_YEAST Uncharacterized protein YNL108C OS=Saccharo... 30 5.8 sp|Q06528|CM4T_STRPE Carmin... 482 DK E V + FE +W ++T + T L ++ W ++F Sbjct: 204 DKFELVKGENESIPFEEREW--KLTMNGNTSFLTNGEEMNWTFMNAF 248 >sp|Q06528|CM4T_STRPE Carmin

  6. Therapeutic potential of proteasome inhibitors in congenital erythropoietic porphyria.

    Science.gov (United States)

    Blouin, Jean-Marc; Duchartre, Yann; Costet, Pierre; Lalanne, Magalie; Ged, Cécile; Lain, Ana; Millet, Oscar; de Verneuil, Hubert; Richard, Emmanuel

    2013-11-05

    Congenital erythropoietic porphyria (CEP) is a rare autosomal recessive disorder characterized by uroporphyrinogen III synthase (UROS) deficiency resulting in massive porphyrin accumulation in blood cells, which is responsible for hemolytic anemia and skin photosensitivity. Among the missense mutations actually described up to now in CEP patients, the C73R and the P248Q mutations lead to a profound UROS deficiency and are usually associated with a severe clinical phenotype. We previously demonstrated that the UROS(C73R) mutant protein conserves intrinsic enzymatic activity but triggers premature degradation in cellular systems that could be prevented by proteasome inhibitors. We show evidence that the reduced kinetic stability of the UROS(P248Q) mutant is also responsible for increased protein turnover in human erythroid cells. Through the analysis of EGFP-tagged versions of UROS enzyme, we demonstrate that both UROS(C73R) and UROS(P248Q) are equally destabilized in mammalian cells and targeted to the proteasomal pathway for degradation. We show that a treatment with proteasomal inhibitors, but not with lysosomal inhibitors, could rescue the expression of both EGFP-UROS mutants. Finally, in CEP mice (Uros(P248Q/P248Q)) treated with bortezomib (Velcade), a clinically approved proteasome inhibitor, we observed reduced porphyrin accumulation in circulating RBCs and urine, as well as reversion of skin photosensitivity on bortezomib treatment. These results of medical importance pave the way for pharmacologic treatment of CEP disease by preventing certain enzymatically active UROS mutants from early degradation by using proteasome inhibitors or chemical chaperones.

  7. A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.

    Science.gov (United States)

    Huang, Kai-Fa; Wang, Yu-Ruei; Chang, En-Cheng; Chou, Tsung-Lin; Wang, Andrew H-J

    2008-04-01

    QCs (glutaminyl cyclases; glutaminyl-peptide cyclotransferases, EC 2.3.2.5) catalyse N-terminal pyroglutamate formation in numerous bioactive peptides and proteins. The enzymes were reported to be involved in several pathological conditions such as amyloidotic disease, osteoporosis, rheumatoid arthritis and melanoma. The crystal structure of human QC revealed an unusual H-bond (hydrogen-bond) network in the active site, formed by several highly conserved residues (Ser(160), Glu(201), Asp(248), Asp(305) and His(319)), within which Glu(201) and Asp(248) were found to bind to substrate. In the present study we combined steady-state enzyme kinetic and X-ray structural analyses of 11 single-mutation human QCs to investigate the roles of the H-bond network in catalysis. Our results showed that disrupting one or both of the central H-bonds, i.e., Glu(201)...Asp(305) and Asp(248)...Asp(305), reduced the steady-state catalysis dramatically. The roles of these two COOH...COOH bonds on catalysis could be partly replaced by COOH...water bonds, but not by COOH...CONH(2) bonds, reminiscent of the low-barrier Asp...Asp H-bond in the active site of pepsin-like aspartic peptidases. Mutations on Asp(305), a residue located at the centre of the H-bond network, raised the K(m) value of the enzyme by 4.4-19-fold, but decreased the k(cat) value by 79-2842-fold, indicating that Asp(305) primarily plays a catalytic role. In addition, results from mutational studies on Ser(160) and His(319) suggest that these two residues might help to stabilize the conformations of Asp(248) and Asp(305) respectively. These data allow us to propose an essential proton transfer between Glu(201), Asp(305) and Asp(248) during the catalysis by animal QCs.

  8. Neutron Detector Signal Processing to Calculate the Effective Neutron Multiplication Factor of Subcritical Assemblies

    Energy Technology Data Exchange (ETDEWEB)

    Talamo, Alberto [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Gohar, Yousry [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division

    2016-06-01

    This report describes different methodologies to calculate the effective neutron multiplication factor of subcritical assemblies by processing the neutron detector signals using MATLAB scripts. The subcritical assembly can be driven either by a spontaneous fission neutron source (e.g. californium) or by a neutron source generated from the interactions of accelerated particles with target materials. In the latter case, when the particle accelerator operates in a pulsed mode, the signals are typically stored into two files. One file contains the time when neutron reactions occur and the other contains the times when the neutron pulses start. In both files, the time is given by an integer representing the number of time bins since the start of the counting. These signal files are used to construct the neutron count distribution from a single neutron pulse. The built-in functions of MATLAB are used to calculate the effective neutron multiplication factor through the application of the prompt decay fitting or the area method to the neutron count distribution. If the subcritical assembly is driven by a spontaneous fission neutron source, then the effective multiplication factor can be evaluated either using the prompt neutron decay constant obtained from Rossi or Feynman distributions or the Modified Source Multiplication (MSM) method.

  9. On-line charge breeding using ECRIS and EBIS

    Science.gov (United States)

    Vondrasek, Richard

    2016-06-01

    The efficient and rapid production of a high-quality, pure beam of highly charged ions is at the heart of any radioactive ion beam facility. Whether an electron cyclotron resonance (ECR) ion source or an electron beam ion source (EBIS) is used to produce these highly charged ions, their operating characteristics will set the boundaries on the range of experiments which can be performed. In addition, time structure and duty cycle have to be considered when defining the operating parameters of the accelerator system as a whole. At Argonne National Laboratory (ANL), an ECR charge breeder was developed as part of the Californium Rare Ion Breeder Upgrade (CARIBU) program. The charge breeding efficiency and high charge state production of the source is at the forefront of ECR charge breeders, but its overall performance as part of the accelerator system is limited by pervasive background and relatively long breeding times. As such, an EBIS charge breeder has been developed and is running in an off-line configuration. It has already demonstrated good breeding efficiencies, shorter residence times, and reduced background and is scheduled to replace the ECR charge breeder in late 2015. The resultant change in duty cycle and time structure necessitates changes to the overall operation of the facility. The experiences with these breeders, as well as from several other facilities which already utilize an ECR or EBIS for charge breeding, help to define the operational characteristics of each technology - their strengths, their weaknesses, and the possible paths to improvement.

  10. γ -soft Ba146 and the role of nonaxial shapes at N90

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, A. J.; Lister, C. J.; McCutchan, E. A.; Albers, M.; Ayangeakaa, A. D.; Bertone, P. F.; Carpenter, M. P.; Chiara, C. J.; Chowdhury, P.; Clark, J. A.; Copp, P.; David, H. M.; Deo, A. Y.; DiGiovine, B.; D' Olympia, N.; Dungan, R.; Harding, R. D.; Harker, J.; Hota, S. S.; Janssens, R. V. F.; Kondev, F. G.; Liu, S. H.; Ramayya, A. V.; Rissanen, J.; Savard, G.; Seweryniak, D.; Shearman, R.; Sonzogni, A. A.; Tabor, S. L.; Walters, W. B.; Wang, E.; Zhu, S.

    2016-01-01

    Low-spin states in the neutron-rich, N=90 nuclide Ba146 were populated following β decay of Cs146, with the goal of clarifying the development of deformation in barium isotopes through delineation of their nonyrast structures. Fission fragments of Cs146 were extracted from a 1.7-Ci Cf252 source and mass selected using the CAlifornium Rare Ion Breeder Upgrade (CARIBU) facility. Low-energy ions were deposited at the center of a box of thin β detectors, surrounded by a highly efficient high-purity Ge array. The new Ba146 decay scheme now contains 31 excited levels extending up to ~2.5 MeV excitation energy, double what was previously known. These data are compared to predictions from the interacting boson approximation (IBA) model. It appears that the abrupt shape change found at N=90 in Sm and Gd is much more gradual in Ba and Ce, due to an enhanced role of the γ degree of freedom.

  11. Significant relationships among frost tolerance and net photosynthetic rate, water use efficiency and dehydrin accumulation in cold-treated winter oilseed rapes.

    Science.gov (United States)

    Urban, Milan Oldřich; Klíma, Miroslav; Vítámvás, Pavel; Vašek, Jakub; Hilgert-Delgado, Alois Albert; Kučera, Vratislav

    2013-12-15

    Five winter oilseed rape cultivars (Benefit, Californium, Cortes, Ladoga, Navajo) were subjected to 30 days of cold treatment (4 °C) to examine the effect of cold on acquired frost tolerance (FT), dehydrin (DHN) content, and photosynthesis-related parameters. The main aim of this study was to determine whether there are relationships between FT (expressed as LT50 values) and the other parameters measured in the cultivars. While the cultivar Benefit accumulated two types of DHNs (D45 and D35), the other cultivars accumulated three additional DHNs (D97, D47, and D37). The similar-sized DHNs (D45 and D47) were the most abundant; the others exhibited significantly lower accumulations. The highest correlations were detected between LT50 and DHN accumulation (r=-0.815), intrinsic water use efficiency (WUEi; r=-0.643), net photosynthetic rate (r=-0.628), stomatal conductance (r=0.511), and intracellular/intercellular CO2 concentration (r=0.505). Those cultivars that exhibited higher Pn rate in cold (and further a significant increase in WUEi) had higher levels of DHNs and also higher FT. No significant correlation was observed between LT50 and E, PRI, or NDVI. Overall, we have shown the selected physiological parameters to be able to distinguish different FT cultivars of winter oilseed rape.

  12. Studies of Beta-Delayed Neutron Emission using Trapped Ions

    Science.gov (United States)

    Siegl, Kevin; Aprahamian, A.; Scielzo, N. D.; Savard, G.; Clark, J. A.; Levand, A. F.; Burkey, M.; Caldwell, S.; Czeszumska, A.; Hirsh, T. Y.; Kolos, K.; Marley, S. T.; Morgan, G. E.; Norman, E. B.; Nystrom, A.; Orford, R.; Padgett, S.; Pérez Galván, A.; Sh, K. S.; Strauss, S. Y.; Wang, B. S.

    2017-01-01

    Using a radio-frequency quadrupole ion trap to confine radioactive ions allows indirect measurements of beta-delayed neutron (BDN) emission. By determining the recoil energy of the beta-decay daughter ions it is possible to study BDN emission, as the neutron emission can impart a significantly larger nuclear recoil than from beta-decay alone. This method avoids most of the systematic uncertainties associated with direct neutron detection but introduces dependencies on the specifics of the decay and interactions of the ion with the RF fields. The decays of seven BDN precursors were studied using the Beta-decay Paul Trap (BPT) to confine fission fragments from the Californium Rare Isotope Breeder Upgrade (CARIBU) facility at Argonne National Laboratory. The analysis of these measurements and results for the branching ratios and neutron energy spectra will be presented. Supported by the NSF under grant PHY-1419765, and the U.S. DOE under the NEUP project 13-5485, contracts DE-AC02-06CH11357 (ANL) and DE-AC52-07NA27344 (LLNL), and award DE-NA0000979 (NNSA).

  13. Production of Medical Radioisotopes in the ORNL High Flux Isotope Reactor (HFIR) for Cancer Treatment and Arterial Restenosis Therapy after PTCA

    Science.gov (United States)

    Knapp, F. F. Jr.; Beets, A. L.; Mirzadeh, S.; Alexander, C. W.; Hobbs, R. L.

    1998-06-01

    The High Flux Isotope Reactor (HFIR) at the Oak Ridge National Laboratory (ORNL) represents an important resource for the production of a wide variety of medical radioisotopes. In addition to serving as a key production site for californium-252 and other transuranic elements, important examples of therapeutic radioisotopes which are currently routinely produced in the HFIR for distribution include dysprosium-166 (parent of holmium-166), rhenium-186, tin-117m and tungsten-188 (parent of rhenium-188). The nine hydraulic tube (HT) positions in the central high flux region permit the insertion and removal of targets at any time during the operating cycle and have traditionally represented a major site for production of medical radioisotopes. To increase the irradiation capabilities of the HFIR, special target holders have recently been designed and fabricated which will be installed in the six Peripheral Target Positions (PTP), which are also located in the high flux region. These positions are only accessible during reactor refueling and will be used for long-term irradiations, such as required for the production of tin-117m and tungsten-188. Each of the PTP tubes will be capable of housing a maximum of eight HT targets, thus increasing the total maximum number of HT targets from the current nine, to a total of 57. In this paper the therapeutic use of reactor-produced radioisotopes for bone pain palliation and vascular brachytherapy and the therapeutic medical radioisotope production capabilities of the ORNL HFIR are briefly discussed.

  14. Extraction studies of selected actinide ions from aqueous solutions with 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione and tri-n-octylphosphine oxide

    Energy Technology Data Exchange (ETDEWEB)

    Hannink, N.J.; Hoffman, D.C. [Lawrence Berkeley Lab., CA (United States)]|[California Univ., Berkeley, CA (United States). Dept. of Chemistry; Smith, B.F. [Los Alamos National Lab., NM (United States)

    1991-11-01

    The first measurements of distribution coefficients (K{sub d}) for Cm(III), Bk(III), Cf(III), Es(III), and Fm(III) between aqueous perchlorate solutions and solutions of 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT) and the synergist tri-n-octylphosphine oxide (TOPO) in toluene are reported. Curium-243, berkelium-250, californium-249, einsteinium-254, and fermium-253 were used in these studies. The K{sub d} for {sup 241}Am was also measured and is in agreement with previously published results. Our new results show that the K{sub d}`s decrease gradually with increasing atomic number for the actinides with a dip at Cf. In general, the K{sub d}`s for these actinides are about a factor of 5 to 10 greater than the K{sub d}`s for the homologous lanthanides at a pH of 2.9, a BMPPT concentration of 0.2 M, and a TOPO concentration of 0.04 M. The larger K{sub d}`s for the actinides are consistent with greater covalent bonding between the actinide metal ion and the sulfur bonding site in the ligand.

  15. Extraction studies of selected actinide ions from aqueous solutions with 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione and tri-n-octylphosphine oxide

    Energy Technology Data Exchange (ETDEWEB)

    Hannink, N.J.; Hoffman, D.C. (Lawrence Berkeley Lab., CA (United States) California Univ., Berkeley, CA (United States). Dept. of Chemistry); Smith, B.F. (Los Alamos National Lab., NM (United States))

    1991-11-01

    The first measurements of distribution coefficients (K{sub d}) for Cm(III), Bk(III), Cf(III), Es(III), and Fm(III) between aqueous perchlorate solutions and solutions of 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT) and the synergist tri-n-octylphosphine oxide (TOPO) in toluene are reported. Curium-243, berkelium-250, californium-249, einsteinium-254, and fermium-253 were used in these studies. The K{sub d} for {sup 241}Am was also measured and is in agreement with previously published results. Our new results show that the K{sub d}'s decrease gradually with increasing atomic number for the actinides with a dip at Cf. In general, the K{sub d}'s for these actinides are about a factor of 5 to 10 greater than the K{sub d}'s for the homologous lanthanides at a pH of 2.9, a BMPPT concentration of 0.2 M, and a TOPO concentration of 0.04 M. The larger K{sub d}'s for the actinides are consistent with greater covalent bonding between the actinide metal ion and the sulfur bonding site in the ligand.

  16. Extraction studies of selected actinide ions from aqueous solutions with 4-benzoyl-2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione and Tri-n-octylphosphine oxide

    Energy Technology Data Exchange (ETDEWEB)

    Hannink, N.J.; Hoffman, D.C. [Lawrence Berkeley Lab., CA (United States); Smith, B.F. [Los Alamos National Lab., NM (United States)

    1992-07-01

    The first measurements of distribution coefficients (k{sub d}) for Cm(III), Bk(III), Cf(III), Es(III), and Fm(III) between aqueous perchlorate solutions and solutions of 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT) and the synergist tri-n-octylphosphine oxide (TOPO) in toluene are reported. Curium-243, berkelium-250, californium-249, einsteinium-254, and fermium-253 were used in these studies. The K{sub d} for {sup 241}Am was also measured and is in agreement with previously published results. Our new results show that the K{sub d}`s decrease gradually with increasing atomic number for the actinides with a dip at Cf. In general, the K{sub d}`s for these actinides are about about a factor of 10 greater than the K{sub d}`s for the homologous lanthanides at a pH of 2.9, a BMPPT concentration of 0.2 M, and a TOPO concentration of 0.04 M. The larger K{sub d}`s for the actinides are consistent with greater covalent bonding between the actinide metal ion and the sulfur bonding site in the ligand. 9 refs., 2 figs., 1 tab.

  17. Recovery and chemical purification of actinides at JRC, Karlsruhe

    Science.gov (United States)

    Bokelund, H.; Apostolidis, C.; Glatz, J.-P.

    1989-07-01

    The application of actinide elements in research and in technology is many times subject to rather stringent purity requirements; often a nuclear grade quality is specified. The additional possible demand for a high isotopic purity is a special feature in the handling of these elements. The amount of actinide elements contained in or adhering to materials declared as waste should be low for safety reasons and out of economic considerations. The release of transuranium elements to the environment must be kept negligible. For these and for other reasons a keen interest in the separation of actinides from various materials exists, either for a re-use through recycling, or for their safe confinement in waste packages. This paper gives a short review of the separation methods used for recovery and purification of actinide elements over the past years in the European Institute for Transuranium Elements. The methods described here involve procedures based on precipitation, ion exchange or solvent extraction; often used in a combination. The extraction methods were preferably applied in a Chromatographie column mode. The actinide elements purified and/or separated from each other by the above methods include uranium, neptunium, plutonium, americium, curium, and californium. For the various elements the work was undertaken with different aims, ranging from reprocessing and fabrication of nuclear fuels on a kilogramme scale, over the procurement of alpha-free waste, to the preparation of neutron sources of milligramme size.

  18. Production of medical radioisotopes in the ORNL High Flux Isotope Reactor (HFIR) for cancer treatment and arterial restenosis therapy after PTCA

    Energy Technology Data Exchange (ETDEWEB)

    Knapp, F.F. Jr.; Beets, A.L.; Mirzadeh, S.; Alexander, C.W.; Hobbs, R.L.

    1998-06-01

    The High Flux Isotope Reactor (HFIR) at the Oak Ridge National Laboratory (ORNL) represents an important resource for the production of a wide variety of medical radioisotopes. In addition to serving as a key production site for californium-252 and other transuranic elements, important examples of therapeutic radioisotopes which are currently routinely produced in the HFIR for distribution include dysprosium-166 (parent of holmium-166), rhenium-186, tin-117m and tungsten-188 (parent of rhenium-188). The nine hydraulic tube (HT) positions in the central high flux region permit the insertion and removal of targets at any time during the operating cycle and have traditionally represented a major site for production of medical radioisotopes. To increase the irradiation capabilities of the HFIR, special target holders have recently been designed and fabricated which will be installed in the six Peripheral Target Positions (PTP), which are also located in the high flux region. These positions are only accessible during reactor refueling and will be used for long-term irradiations, such as required for the production of tin-117m and tungsten-188. Each of the PTP tubes will be capable of housing a maximum of eight HT targets, thus increasing the total maximum number of HT targets from the current nine, to a total of 57. In this paper the therapeutic use of reactor-produced radioisotopes for bone pain palliation and vascular brachytherapy and the therapeutic medical radioisotope production capabilities of the ORNL HFIR are briefly discussed.

  19. Compensated bismuth-loaded plastic scintillators for neutron detection using low-energy pseudo-spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Dumazert, Jonathan, E-mail: jonathan.dumazert@cea.fr [CEA, LIST, Laboratoire Capteurs Architectures Electroniques, 91191 Gif-sur-Yvette (France); Coulon, Romain; Bertrand, Guillaume H.V.; Normand, Stéphane [CEA, LIST, Laboratoire Capteurs Architectures Electroniques, 91191 Gif-sur-Yvette (France); Méchin, Laurence [CNRS, UCBN, Groupe de Recherche en Informatique, Image, Automatique et Instrumentation de Caen, 14050 Caen (France); Hamel, Matthieu [CEA, LIST, Laboratoire Capteurs Architectures Electroniques, 91191 Gif-sur-Yvette (France)

    2016-05-21

    Gadolinium-covered modified plastic scintillators show a high potential for the deployment of cost-effective neutron detectors. Taking advantage of the low-energy photon and electron signature of thermal neutron captures in gadolinium-155 and gadolinium-157 however requires a background correction. In order to display a trustable rate, dual compensation schemes appear as an alternative to Pulse Shape Discrimination. This paper presents the application of such a compensation scheme to a two-bismuth loaded plastic scintillator system. A detection scintillator interacts with incident photon and fast neutron radiations and is covered with a gadolinium converter to become thermal neutron-sensitive as well. In the meantime, an identical compensation scintillator, covered with terbium, solely interacts with the photon and fast neutron part of incident radiations. After the acquisition and the treatment of the counting signals from both sensors, a hypothesis test determines whether the resulting count rate after subtraction falls into statistical fluctuations or provides a robust image of neutron activity. A laboratory prototype is tested under both photon and neutron radiations, allowing us to investigate the performance of the overall compensation system. The study reveals satisfactory results in terms of robustness to a cesium-137 background and in terms of sensitivity in presence of a californium-252 source.

  20. Fast neutron tomography with real-time pulse-shape discrimination in organic scintillation detectors

    Science.gov (United States)

    Joyce, Malcolm J.; Agar, Stewart; Aspinall, Michael D.; Beaumont, Jonathan S.; Colley, Edmund; Colling, Miriam; Dykes, Joseph; Kardasopoulos, Phoevos; Mitton, Katie

    2016-10-01

    A fast neutron tomography system based on the use of real-time pulse-shape discrimination in 7 organic liquid scintillation detectors is described. The system has been tested with a californium-252 source of dose rate 163 μSv/h at 1 m and neutron emission rate of 1.5×107 per second into 4π and a maximum acquisition time of 2 h, to characterize two 100×100×100 mm3 concrete samples. The first of these was a solid sample and the second has a vertical, cylindrical void. The experimental data, supported by simulations with both Monte Carlo methods and MATLAB®, indicate that the presence of the internal cylindrical void, corners and inhomogeneities in the samples can be discerned. The potential for fast neutron assay of this type with the capability to probe hydrogenous features in large low-Z samples is discussed. Neutron tomography of bulk porous samples is achieved that combines effective penetration not possible with thermal neutrons in the absence of beam hardening.

  1. A review of neutron scattering correction for the calibration of neutron survey meters using the shadow cone method

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sang In; Kim, Bong Hwan; Kim, Jang Lyul; Lee, Jung Il [Health Physics Team, Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-12-15

    The calibration methods of neutron-measuring devices such as the neutron survey meter have advantages and disadvantages. To compare the calibration factors obtained by the shadow cone method and semi-empirical method, 10 neutron survey meters of five different types were used in this study. This experiment was performed at the Korea Atomic Energy Research Institute (KAERI; Daejeon, South Korea), and the calibration neutron fields were constructed using a {sup 252}Californium ({sup 252}Cf) neutron source, which was positioned in the center of the neutron irradiation room. The neutron spectra of the calibration neutron fields were measured by a europium-activated lithium iodide scintillator in combination with KAERI's Bonner sphere system. When the shadow cone method was used, 10 single moderator-based survey meters exhibited a smaller calibration factor by as much as 3.1 - 9.3% than that of the semi-empirical method. This finding indicates that neutron survey meters underestimated the scattered neutrons and attenuated neutrons (i.e., the total scatter corrections). This underestimation of the calibration factor was attributed to the fact that single moderator-based survey meters have an under-ambient dose equivalent response in the thermal or thermal-dominant neutron field. As a result, when the shadow cone method is used for a single moderator-based survey meter, an additional correction and the International Organization for Standardization standard 8529-2 for room-scattered neutrons should be considered.

  2. Active Neutron Interrogation of Non-Radiological Materials with NMIS

    Energy Technology Data Exchange (ETDEWEB)

    Walker, Mark E [ORNL; Mihalczo, John T [ORNL

    2012-02-01

    The Nuclear Materials Identification System (NMIS) at Oak Ridge National Laboratory (ORNL), although primarily designed for analyzing special nuclear material, is capable of identifying nonradiological materials with a wide range of measurement techniques. This report demonstrates four different measurement methods, complementary to fast-neutron imaging, which can be used for material identification: DT transmission, DT scattering, californium transmission, and active time-tagged gamma spectroscopy. Each of the four techniques was used to evaluate how these methods can be used to identify four materials: aluminum, polyethylene, graphite, and G-10 epoxy. While such measurements have been performed individually in the past, in this project, all four measurements were performed on the same set of materials. The results of these measurements agree well with predicted results. In particular, the results of the active gamma spectroscopy measurements demonstrate the technique's applicability in a future version of NMIS which will incorporate passive and active gamma-ray spectroscopy. This system, designated as a fieldable NMIS (FNMIS), is under development by the US Department of Energy Office of Nuclear Verification.

  3. X-ray Measurements of a Thermo Scientific P385 DD Neutron Generator

    Energy Technology Data Exchange (ETDEWEB)

    E.H. Seabury; D.L. Chichester; A.J. Caffrey; J. Simpson; M. Lemchak; C.J. Wharton

    2001-08-01

    Idaho National Laboratory is experimenting with electrical neutron generators, as potential replacements for californium-252 radioisotopic neutron sources in its PINS prompt gamma-ray neutron activation analysis (PGNAA) system for the identification of military chemical warfare agents and explosives. In addition to neutron output, we have recently measured the x-ray output of the Thermo Scientific P385 deuterium-deuterium neutron generator. X-rays are a normal byproduct from a neutron generator and depending on their intensity and energy they can interfere with gamma rays from the object under test, increase gamma-spectrometer dead time, and reduce PGNAA system throughput. The P385 x-ray energy spectrum was measured with a high-purity germanium (HPGe) detector, and a broad peak is evident at about 70 keV. To identify the source of the x-rays within the neutron generator assembly, it was scanned by collimated scintillation detectors along its long axis. At the strongest x-ray emission points, the generator also was rotated 60° between measurements. The scans show the primary source of x-ray emission from the P385 neutron generator is an area 60 mm from the neutron production target, in the vicinity of the ion source. Rotation of the neutron generator did not significantly alter the x-ray count rate, and the x-ray emission appears to be axially symmetric within the neutron generator.

  4. An Account of Oak Ridge National Laboratory's Thirteen Research Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, Murray Wilford [ORNL

    2009-08-01

    The Oak Ridge National Laboratory has built and operated 13 nuclear reactors in its 66-year history. The first was the graphite reactor, the world's first operational nuclear reactor, which served as a plutonium production pilot plant during World War II. It was followed by two aqueous-homogeneous reactors and two red-hot molten-salt reactors that were parts of power-reactor development programs and by eight others designed for research and radioisotope production. One of the eight was an all-metal fast burst reactor used for health physics studies. All of the others were light-water cooled and moderated, including the famous swimming-pool reactor that was copied dozens of times around the world. Two of the reactors were hoisted 200 feet into the air to study the shielding needs of proposed nuclear-powered aircraft. The final reactor, and the only one still operating today, is the High Flux Isotope Reactor (HFIR) that was built particularly for the production of californium and other heavy elements. With the world's highest flux and recent upgrades that include the addition of a cold neutron source, the 44-year-old HFIR continues to be a valuable tool for research and isotope production, attracting some 500 scientific visitors and guests to Oak Ridge each year. This report describes all of the reactors and their histories.

  5. Test and evaluation results of the /sup 252/Cf shuffler at the Savannah River Plant

    Energy Technology Data Exchange (ETDEWEB)

    Crane, T.W.

    1981-03-01

    The /sup 252/Cf Shuffler, a nondestructive assay instrument employing californium neutron source irradiation and delayed-neutron counting, was developed for measuring /sup 235/U content of scrap and waste items generated at the Savannah River Plant (SRP) reactor fuel fabrication facility. The scrap and waste items include high-purity uranium-aluminum alloy ingots as well as pieces of castings, saw and lathe chips from machining operations, low-purity items such as oxides of uranium or uranium intermixed with flux materials found in recovery operations, and materials not recoverable at SRP such as floor sweepings or residues from the uranium scrap recovery operation. The uranium contains about 60% /sup 235/U with the remaining isotopes being /sup 236/U, /sup 238/U, and /sup 234/U in descending order. The test and evaluation at SRP concluded that the accuracy, safety, reliability, and ease of use made the /sup 252/Cf Shuffler a suitable instrument for routine use in an industrial, production-oriented plant.

  6. Compensated bismuth-loaded plastic scintillators for neutron detection using low-energy pseudo-spectroscopy

    Science.gov (United States)

    Dumazert, Jonathan; Coulon, Romain; Bertrand, Guillaume H. V.; Normand, Stéphane; Méchin, Laurence; Hamel, Matthieu

    2016-05-01

    Gadolinium-covered modified plastic scintillators show a high potential for the deployment of cost-effective neutron detectors. Taking advantage of the low-energy photon and electron signature of thermal neutron captures in gadolinium-155 and gadolinium-157 however requires a background correction. In order to display a trustable rate, dual compensation schemes appear as an alternative to Pulse Shape Discrimination. This paper presents the application of such a compensation scheme to a two-bismuth loaded plastic scintillator system. A detection scintillator interacts with incident photon and fast neutron radiations and is covered with a gadolinium converter to become thermal neutron-sensitive as well. In the meantime, an identical compensation scintillator, covered with terbium, solely interacts with the photon and fast neutron part of incident radiations. After the acquisition and the treatment of the counting signals from both sensors, a hypothesis test determines whether the resulting count rate after subtraction falls into statistical fluctuations or provides a robust image of neutron activity. A laboratory prototype is tested under both photon and neutron radiations, allowing us to investigate the performance of the overall compensation system. The study reveals satisfactory results in terms of robustness to a cesium-137 background and in terms of sensitivity in presence of a californium-252 source.

  7. Measurement of neutron dose and spectra at light-water reactors

    Energy Technology Data Exchange (ETDEWEB)

    Soldat, K.L.; Endres, G.W.R.; Cummings, F.M.

    1982-08-01

    In choosing one dosimeter over another, both sensitivity and precision must be addressed. It has been determined that dosimeters employing NTA film lack adequate sensitivity for use inside containment of nuclear plants. From this study, it is apparent that CR-39 and polycarbonate track etch films used without radiators are also inadequate. The rest of the dosimeters tested displayed adequate sensitivity. The two general types of dosimeters which comprise that group are: (1) TLDs and (2) the polycarbonate track etch which was used in conjunction with (n, ..cap alpha..) radiators. The precision of the TLD dosimeter depends on the calibration technique and response correction technique. TLD dosimeters calibrated to D/sub 2/O-moderated californium-252 or corrected based on 9- to 3-in. sphere response rates seemed to function best inside reactor containment. Polycarbonate track etch film with (n, ..cap alpha..) radiators was found to be sensitive enough for use inside reactor containment; however, the standard deviation for the results was roughly twice the value of the most precise TLD albedo dosimeters. Also, several of the polycarbonate dosimeters saturated, rendering any evaluation impossible.

  8. Report on the workshop "Decay spectroscopy at CARIBU: advanced fuel cycle applications, nuclear structure and astrophysics". 14-16 April 2011, Argonne National Laboratory, USA.

    Energy Technology Data Exchange (ETDEWEB)

    Kondev, F.; Carpenter, M.P.; Chowdhury, P.; Clark, J.A.; Lister, C.J.; Nichols, A.L.; Swewryniak, D. (Nuclear Engineering Division); (Univ. of Massachusetts); (Univ. of Surrey)

    2011-10-06

    A workshop on 'Decay Spectroscopy at CARIBU: Advanced Fuel Cycle Applications, Nuclear Structure and Astrophysics' will be held at Argonne National Laboratory on April 14-16, 2011. The aim of the workshop is to discuss opportunities for decay studies at the Californium Rare Isotope Breeder Upgrade (CARIBU) of the ATLAS facility with emphasis on advanced fuel cycle (AFC) applications, nuclear structure and astrophysics research. The workshop will consist of review and contributed talks. Presentations by members of the local groups, outlining the status of relevant in-house projects and availabile equipment, will also be organized. time will also be set aside to discuss and develop working collaborations for future decay studies at CARIBU. Topics of interest include: (1) Decay data of relevance to AFC applications with emphasis on reactor decay heat; (2) Discrete high-resolution gamma-ray spectroscopy following radioactive decya and related topics; (3) Calorimetric studies of neutron-rich fission framgents using Total ABsorption Gamma-Ray Spectrometry (TAGS) technique; (4) Beta-delayed neutron emissions and related topics; and (5) Decay data needs for nuclear astrophysics.

  9. Neutron activation determination of gold in technogenic raw materials with different mineral composition

    Directory of Open Access Journals (Sweden)

    Yudakov Aleksandr A.

    2015-01-01

    Full Text Available The methods used to determine the gold content in the technogenic objects of gold mining were analyzed regarding their non-homogeneity and complexity of chemical and mineral compositions. A possible application of the neutron activation analysis with the use of the californium source of neutrons for determining the content of fine-grained and extra-fine-grained gold in the technogenic objects, including the bottom-ash waste of energy providers, is considered. It was demonstrated that the chemical composition of the sample affects the neuron flux distribution in the sample, which can essentially distort the results of the neutron activation analysis. In order to eliminate possible systematic errors investigations of the effect of the sample mineral composition on the results of the gold determination using the neutron activation analysis were carried out. Namely, a large mass of rock (3-5 kg was loaded into an activation zone using four matrix types such as silicate, carbon-containing, iron-containing, and titanium magnetite. It was shown that there wereno significant difference between the dispersal of the fluxes of thermal and resonance neutrons emitted from 252Cf during activation of the gold-containing technogenic samples with different mineral compositions.

  10. Preliminary studies for the Development of S.E.T.U.P. : "Experimental and Theoretical Simulations Useful for Planetology"

    Science.gov (United States)

    Arzoumanian, E.; Es-Sebbar, Et.; Romanzin, C.; Perrier, S.; Bénilan, Y.; Gazeau, M.-C.

    2008-09-01

    This paper presents studies performed in the frame of the SETUP program (a French acronym for Experimental and Theoretical Simulations Useful for Planetology). The final goal of this project is to perform representative simulations of Titan's atmosphere and to be able to determine the physicochemical processes involved in its atmosphere. The simulation experiments will be performed in a reactor where an initial gas mixture will be exposed, for the first time, to both major energy sources (electrons and photons) that are responsible for the chemical evolution of Titan's atmosphere. Thus, the complex chemistry between N atoms and CH3, CH2, CH fragments, issued from electron dissociation of N2 and photodissociation of CH4 respectively, will be initiated. For these simulation experiments, we are planning to use a pulsed excimer KrF laser delivering photons at 248 nm to dissociate methane via a multiphotonic process because the Lyman-α radiation, mainly responsible for the dissociation of this compound in the upper atmosphere, cannot be easily reproduced in the laboratory. A first attempt to check for the energetic equivalence of the two processes - 2 photons at 248 nm vs. one single photon at Lyman-α - has already been performed and a more extensive re-examination of the methane photolysis at both wavelengths has been undertaken. The available literature indeed provides contradictory results for the methane's primary photolytic scheme at Lyman-α and no studies at all have been performed yet to establish the different photolytic decomposition pathways at 248 nm. One has to note that the available literature provides contradictory results for methane's primary photolytic scheme at Lyman-α and no studies at all have been performed yet to establish the different photolytic decomposition pathways at 248 nm. Thus, a re-examination of the methane photolysis at both wavelengths has been undertaken. Photolysis of methane has been carried out using a photochemical classic

  11. CD151 promotes proliferation of and eNOS expression in human umbilical endothelial cell%CD151蛋白促内皮细胞增殖和eNOS蛋白表达

    Institute of Scientific and Technical Information of China (English)

    彭丹; 左后娟; 秦瑾; 刘正湘; 汪道文

    2011-01-01

    目的 研究CD151及其突变体CD151-ARSA245-248对人脐静脉内皮细胞(HUVEC)增殖及eNOS 表达的影响,探讨CD151促血管生成的机制.方法 构建pAAV-CD151及其突变体CD151-ARSA245-248(囊泡运输缺陷突变体),并转染HUVEC.CCK-8法测定HUVEC增殖的能力,Western Blot检测CD151及eNOS蛋白的表达.结果 pAAV-CD151组及pAAV- CD151-ARSA245-248组CD151蛋白表达均增加,显著高于正常对照组和pAAV-GFP组(P<0.05),但pAAV-CD151组及pAAV- CD151-ARSA245-248组之间CD151蛋白表达没有统计学意义(P>0.05).CCK-8法测定HUVEC增殖能力亦无统计学意义(P>0.05).正常对照组,pAAV-GFP组,pAAV-CD151组及pAAV-CD151-ARSA245-248突变体组的OD值分别为1.393±1.68、1.498±1.746、2.346±2.52和1.71±1.863,pAAV-CD151组较pAAV-GFP组和正常对照组细胞增殖能力明显增强(P<0.01),pAAV-CD151 -ARSA245-248组较pAAV-CD151组细胞增殖能力减弱(P<0.05).此外,pAAV-CD151组eNOS蛋白表达较pAAV-GFP组和正常对照组明显增加(P<0.01),pAAV-CD151 -ARSA245-248组较pAAV-CD151组eNOS蛋白表达降低(P<0.05).结论 CD151是促细胞增殖的重要蛋白质,CD151影响eNOS信号通路的激活.上述机制可能为CD151促血管生成的重要机制之一.%Objective To investigate the effect of CD151 and CD151- ARSA245-248 mutant on the proliferation of human umbilical vein endothelial cells (HUVEC) and eNOS phosphorylation. Methods We constructed pAAV-CD151 and pAAV-CD151 pAAV_CD151_ARSA245-248 mutant, and transfected HUVECs mediated with Fugene HD. After transfection, the expressions of CD 151 , eNOS and phospho-eNOS were measured by western blot. Proliferation of HUVECs was measured by Cell Counting Kit-8 assay. Results The expression of CD151 protein in pAAV-CD151, pAAV_CD151_ARSAp245-248 groups were significantly higher than in the control group and pAAV-GFP group (P<0. 05). The OD values in control, pAAV-GFP, pAAV-CD151, pAAV-CD151-ARSA245-248 groups were 1. 393 ±1. 685 , 1. 498

  12. A Survey and Analysis on Dietary Behavior of Children Aged 3-6 in a Community of Shanghai%上海市某社区3~6岁儿童饮食行为调查分析

    Institute of Scientific and Technical Information of China (English)

    汤红梅; 何丹丹; 严玉洁; 方红; 周洁

    2012-01-01

    [Objective] To understand the dietary behavior of children aged 3-6 years old and the relevant family factors to provide scientific basis for developing effective intervention programs. [ Methods ] A total of 254 parents of kindergarten children in Minhang district were selected by random cluster sampling, and the information of dietary behavior issues and influencing factors was collected through questionnaire, with 248 questionnaires available. [ Results ] According to the questionnaire, 36.3% of the children (90/248) rendered problematic dietary habits, 4,8% of them (12/248) did not have breakfast every morning, and the top three unhealthy dietary habits were eating snacks (76.6%), being half-hearted during meals (62.1%), and picky eating (48.0%). In addition, 38.7% of them (96/248) took breakfast in poor quality. They mostly consumed traditional cereals for break fast instead of food with high quality protein. There was a significant positive correlation between children's dietary habits and parents'(r=0.262, r = 0.309; P<0.01). [ Conclusion ] Among the children aged 3-6 years old in this community, the overall quality of breakfast was not high, and more than 1/3 of them rendered unhealthy eating habits. The direct factor influencing children's dietary habits is derived from their parents, so the education of dietary behavior delivered to parents is critical and need to be strengthened.%[目的]了解上海市某社区3~6岁儿童的饮食行为及其父母对儿童饮食行为的影响,为制定有效的干预措施提供科学依据.[方法]采用整群抽样方法,抽取闵行区某幼儿园254名儿童家长进行问卷调查,回收合格问卷248份,收集儿童饮食行为及影响因素的信息. [结果] 36.3%( 90/248)的儿童饮食行为习惯差,4.8%( 12/248)的儿童不能坚持每天吃早餐;不良饮食行为占前3位的为喜欢吃零食(76.6%)、不专心吃饭(62.1%)和挑食( 48.0%);38.7%( 96/248)的儿童早餐质量较

  13. UV and RIR matrix assisted pulsed laser deposition of organic MEH-PPV films

    DEFF Research Database (Denmark)

    Christensen, Bo Toftmann; Papantonalis, M.R.; Auyeung, R.C.Y.

    2004-01-01

    A comparative study of thin film production based on gentle laser-ablation techniques has been carried out with the luminescent polymer poly [2-methoxy-5-(2'-ethylhexyloxy)-1,4-phenylene vinylene]. Using a free-electron laser films were made by resonant infrared pulsed laser deposition (RIR......-PLD). For the first time resonant infrared matrix assisted pulsed laser evaporation (RIR-MAPLE) was successfully demonstrated on a luminescent polymer system. In addition to this, an excimer laser has been used for UV-MAPLE depositions at 193 and 248-nm irradiation. Films deposited onto NaCl and quartz substrates...... were analyzed by Fourier transform infrared spectroscopy, UV-visible absorbance and photoluminescence. Photoluminescent material was deposited by RIR-MAPLE and 248-nm MAPLE, while the RIR-PLD and 193-nm-MAPLE depositions displayed the smoothest surfaces but did not show photoluminescence. (C) 2003...

  14. Absolute I(asterisk) quantum yields for the ICN A state by diode laser gain-vs-absorption spectroscopy

    Science.gov (United States)

    Hess, Wayne P.; Leone, Stephen R.

    1987-01-01

    Absolute I(asterisk) quantum yields have been measured as a function of wavelength for room temperature photodissociation of the ICN A state continuum. The yields are obtained by the technique of time-resolved diode laser gain-vs-absorption spectroscopy. Quantum yields are evaluated at seven wavelengths from 248 to 284 nm. The yield at 266 nm is 66.0 + or - 2 percent and it falls off to 53.4 + or - 2 percent and 44.0 + or - 4 percent at 284 and 248 nm, respectively. The latter values are significantly higher than those obtained by previous workers using infrared fluorescence. Estimates of I(asterisk) quantum yields obtained from analysis of CN photofragment rotational distributions, as discussed by other workers, are in good agreement with the I(asterisk) yields reported here. The results are considered in conjunction with recent theoretical and experimental work on the CN rotational distributions and with previous I(asterisk) quantum yield results.

  15. Aurora project: optical design for a kilojoule class KrF laser

    Energy Technology Data Exchange (ETDEWEB)

    Hanlon, J.; McLeod, J.; Sollid, J.E.; Horn, W. III; Carmichael, R.; Kortegaard, B.; Woodfin, G.; Rosocha, L..

    1985-01-01

    Aurora is a 248-nm, 10-kilojoule laser system being built at Los Alamos National Laboratory to demonstrate the feasibility of large KrF laser systems for laser fusion. It was designed as a test bed to demonstrate: (1) efficiet energy extraction at 248 nm; (2) an angularly multiplexed optical system that is scaleable to large system designs; (3) the control of parasitics and ASE (amplified spontaneous emission); (4) long path pulse propagation at uv wavelengths; (5) alignment systems for multibeam systems; and (6) new or novel approaches to optical hardware that can lead to cost reduction on large systems. In this paper only issues pertinent to the optical system are addressed. First, a description of the entire system is given. The design constraints on the optical system are explained, concurrent with a discussion of the final design. This is followed by a very brief discussion of coatings; in particular, the use of sol-gels for antireflection coatings is presented.

  16. Drug: D10106 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D10106 Drug Dalantercept (USAN) H3206H4960N904O976S38 37714.6535 37726.7792 DPVKPSR...VLD SDGPFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGK (dimer; disulfide bridge: 13-30, 15-20, 25-48, 56-68, 69-74, 107-107', 110...-110', 1442-202, 248-306, 13'-30', 15'-20', 25'-48', 56'-68', 69'-74', 142'-202', 248...arget-based classification of drugs [BR:br08310] Cytokine receptors TGF-beta receptors ACVRL1 (ALK1) [HSA:94...] [KO:K13594] Dalantercept D10106 Dalantercept (USAN) CAS: 1186210-24-1 PubChem: 135626824 ...

  17. Epigallocatechin-3-gallate rapidly remodels PAP85-120, SEM1(45-107, and SEM2(49-107 seminal amyloid fibrils

    Directory of Open Access Journals (Sweden)

    Laura M. Castellano

    2015-09-01

    Full Text Available Semen harbors amyloid fibrils formed by proteolytic fragments of prostatic acid phosphatase (PAP248-286 and PAP85-120 and semenogelins (SEM1 and SEM2 that potently enhance HIV infectivity. Amyloid but not soluble forms of these peptides enhance HIV infection. Thus, agents that remodel these amyloid fibrils could prevent HIV transmission. Here, we confirm that the green tea polyphenol, epigallocatechin-3-gallate (EGCG, slowly remodels fibrils formed by PAP248-286 termed SEVI (semen derived enhancer of viral infection and also exerts a direct anti-viral effect. We elucidate for the first time that EGCG remodels PAP85-120, SEM1(45-107, and SEM2(49-107 fibrils more rapidly than SEVI fibrils. We establish EGCG as the first small molecule that can remodel all four classes of seminal amyloid. The combined anti-amyloid and anti-viral properties of EGCG could have utility in preventing HIV transmission.

  18. Ternary Amides Containing Transition Metals for Hydrogen Storage: A Case Study with Alkali Metal Amidozincates.

    Science.gov (United States)

    Cao, Hujun; Richter, Theresia M M; Pistidda, Claudio; Chaudhary, Anna-Lisa; Santoru, Antonio; Gizer, Gökhan; Niewa, Rainer; Chen, Ping; Klassen, Thomas; Dornheim, Martin

    2015-11-01

    The alkali metal amidozincates Li4 [Zn(NH2)4](NH2)2 and K2[Zn(NH2)4] were, to the best of our knowledge, studied for the first time as hydrogen storage media. Compared with the LiNH2-2 LiH system, both Li4 [Zn(NH2)4](NH2)2-12 LiH and K2[Zn(NH2)4]-8 LiH systems showed improved rehydrogenation performance, especially K2[Zn(NH2)4]-8 LiH, which can be fully hydrogenated within 30 s at approximately 230 °C. The absorption properties are stable upon cycling. This work shows that ternary amides containing transition metals have great potential as hydrogen storage materials.

  19. 移动软交换IP承载信令及语音带宽计算研究%The Bandwidth Calculation of Mobile Soft Switch Voice and Signaling Over IP

    Institute of Scientific and Technical Information of China (English)

    李元; 张奎; 蔡超

    2012-01-01

      It briefly describes the difference between mobile soft switch signaling and voice over IP technology and the traditional TDM bearer. Based on the R4 network architecture, it expounds the basic concept of H.248, BICC, MAP, CAP, ISUP and BSSAP, and the protocol stack and bandwidth calculation, as wel as the basic concept of Nb interface and the protocol stack and bandwidth calculation.%  简要说明了移动软交换信令、语音IP化后与传统TDM承载的不同;在给出R4网络架构的基础上,详细阐述了H.248、BICC、MAP、CAP、ISUP、BSSAP信令的基本概念、协议栈、带宽计算方法和Nb接口的基本概念、协议栈、带宽计算方法.

  20. Drug: D04004 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D04004 Drug Enoximone (USAN/INN); Perfan (TN) C12H12N2O2S 248.0619 248.3009 D04004....1CE Phosphodiesterase inhibitors C01CE03 Enoximone D04004 Enoximone (USAN/INN) Target-based classification o...0] [KO:K13296] Enoximone [ATC:C01CE03] D04004 Enoximone (USAN/INN) CAS: 77671-31-9 PubChem: 17397999 DrugBan...k: DB04880 LigandBox: D04004 NIKKAJI: J22.780C ATOM 17 1 C8x C 27.7885 -14.9776 2 C8y C 27.7885 -16.3774 3 C

  1. Differences among isolates of simian hemorrhagic fever (SHF) virus.

    Science.gov (United States)

    Gravell, M; London, W T; Leon, M E; Palmer, A E; Hamilton, R S

    1986-01-01

    Simian hemorrhagic fever (SHF) virus is a member of the Togaviridae family which currently is unclassified to genus. We have studied the relatedness of four different SHF virus isolates obtained from infected macaque or patas monkeys. Differences were found among isolates in type and severity of disease produced in patas monkeys, cell sensitivity to infection, viral antigens, and levels of specific antibody induced in patas monkeys. Based on these criteria, the four isolates have been grouped in two categories: those producing acute infections in patas monkeys (LVR, P-180) and those producing persistent infections (P-248, P-741). The P-180 isolate induced the most severe disease in experimentally infected patas monkeys, but only occasionally were their infections fatal. Persistently infected patas monkeys were viremic over a period of years, but showed no signs or symptoms of infection. All four isolates were found to be antigenically related by use of enzyme-linked immunosorbent assay (ELISA); the P-248 isolate showing the weakest antigenic relationship. However, none of the four isolates induced cross-neutralizing antibodies in infected patas monkeys. High titers of specific IgG antibody (up to 31,250 as determined by ELISA) were induced in acutely infected patas monkeys (LVR, P-180), but antibody was barely detectable (less than or equal to 50) in persistently infected patas monkeys (P-248, P-741). LVR lytically infected USU-104 cells, patas monkey peritoneal macrophages (PMAC), and rhesus monkey PMAC. The P-180 isolate lytically infected both patas monkey PMAC and rhesus monkey PMAC, but not USU-104 cells. The isolates producing persistent infections (P-248, P-741) lytically infected only rhesus monkey PMAC. These results show that marked differences exist among isolates of SHF virus from naturally infected animals. These differences should be useful in categorizing new isolates.

  2. Age and sex correlation of Chlamydia trachomatis infections evaluated by the culture technique and by an enzyme immunosorbent assay, IDEIA

    DEFF Research Database (Denmark)

    Østergaard, Lars; Lundemose, AG; Birkelund, Svend

    1990-01-01

    A total number of 1358 patients were examined for genital infections with Chlamydia trachomatis. 252 urethral smears from men and 1106 cervical smears from women were obtained. The average age of infected patients was 24.8 years (females 24.1, males 27.7). The overall prevalence was 10.6% (female.......8% and a specificity of 95.4% when using a cut-off level of 0.05 mean extinction values (MEV), as described by the manufacturer....

  3. Quantification of Femoral Neck Exposure Through a Minimally Invasive Smith-Petersen Approach

    Science.gov (United States)

    2010-06-01

    2004; 429:248 255. 9. Jacobs MA, Goytia RN, Bhargava T. Hip resurfacing through an anterolateral approach: surgical description and early review. J...neck blood supply than the posterior approach during hip resurfacing . J Bone Joint Surg (Br). 2007;89-B: 1293 1298. 11. Swiontkowski MF, Thorpe M, Seiler...approach to the hip . Methods: Ten fresh frozen hemipelves were dissected using a minimally invasive Smith Petersen approach. Upon completion of the

  4. Computers and Mathematics

    Science.gov (United States)

    1989-01-01

    differently. A small interactive program was written using MATLAB to compute determinants. The entries of the matrices 69 were varied in small loops...1985, A. Lascoux, M.P. Schfitzenberger, Formulaire raisonni de fonctions symitriques, L.1.T.P, U.E.R. MATHS, Paris 7, L.A. 248. [Macdonald), I.G...1979, Symmetric functions and Hall polynomials, Clarendon Press, Oxford. [VII 1897, A. Valibouze, Fonctions symitriques et changements de bases

  5. The 1967 Arab-Israeli Six-Day War: An Analysis Using the Principles of War

    Science.gov (United States)

    2007-11-02

    10 Chaim Herzog, The Arab-Israeli Wars, (New York: Vintage Books, 1984), p. 154. 11 Ibid, p. 154. 12 Nadav Safran , Israel-The Embattled Ally...13 Herzog, p. 156. 14 Herzog, p. 154. 15 Safran , p. 246. 16 Dupuy, p. 1231. 17 Safran , p. 248. 8 The Israeli ground offensive, on this front...236. 22 Herzog, p. 184. 23 Safran , p. 256. 10 principles of war provide a useful template in analyzing a conflict. The definitions and descriptions of

  6. Microcontroller-assisted compensation of adenosine triphosphate levels: instrument and method development.

    Science.gov (United States)

    Hu, Jie-Bi; Chen, Ting-Ru; Chen, Yu-Chie; Urban, Pawel L

    2015-01-30

    In order to ascertain optimum conditions for biocatalytic processes carried out in vitro, we have designed a bio-opto-electronic system which ensures real-time compensation for depletion of adenosine triphosphate (ATP) in reactions involving transfer of phosphate groups. The system covers ATP concentration range of 2-48 μM. The report demonstrates feasibility of the device operation using apyrase as the ATP-depleting enzyme.

  7. Visual Accommodation, the Mandelbaum Effect, and Apparent Size.

    Science.gov (United States)

    1979-11-01

    monkeys were awakened, accommodation immediately went to a far distance, followed by accurate accommodation to the - ambient stimuli. Similarly... ambient stimulation is present. Morgan (1957) proposes - two possible conditions in which visual stimuli are reduced to the minimum--in complete darkness...oj Physiology, 1941, 12, 720-733. Otero, J. M. and Duran, Continuacion del estudio de la miopia nocturna. Anales de i y Quimica , 1942, 38, 236-248

  8. Preparation of a Waveguide Array in Flame Hydrolysis Deposited GeO2-SiO2 Glasses by Excimer Laser Irradiation

    Institute of Scientific and Technical Information of China (English)

    吴远大; 邢华; 张乐天; 李爱武; 于永森; 张玉书

    2002-01-01

    SiO2 glass films doped with GeO2 were prepared by the flame hydrolysis deposition method, then annealed at 1200. C. After exposure to high pressure hydrogen, the as-deposited films were irradiated with excimer laser pulses operated at 248nm. The induced refractive index change (the growth of index change was 0.33%) was measured by a spectroscopic ellipsometer. A waveguide array has been written in the film by irradiation through a phase mask.

  9. Proceedings of the Annual Gaseous Electronics Conference (40th) Held in Atlanta Georgia on 13-16 October 1987

    Science.gov (United States)

    1988-07-01

    between 0.1 Torr and 10 Torr, and gene - rates the pulsed plasma at a rep-rate of 60 Hz. The plasma is studied by a Langmuir double probe and an...parameters. In other gas mixtures ex- cime ; radiation was obtained at 147 nm (Kr;), 248 am (KrF ) and 308 m (XeCl ). Our experiments show that it is

  10. 西利宾胺预防抗结核药所致肝损害的临床观察%Clinical observation of Silymarin in the prevention of hepatic lesion induced by antituberculotic

    Institute of Scientific and Technical Information of China (English)

    王玉彬

    2012-01-01

    目的 探讨西利宾胺预防抗结核药引起肝损害的疗效.方法 在我所接受抗结核治疗的患者486人,分为观察组,238例,对照组248例,两组均给予2RHZE/4RH方案抗结核治疗,观察组同时加服西利宾胺治疗,对照组加服肌苷治疗.结果 观察组发生肝损害21例(21/238)占8.8%,对照组发生肝损害64例(64/248)占25.8%两组比较P<0.05.结论 西利宾胺能较好预防治疗抗结核药引起的肝损害,值得临床推广运用.%Objective To explore the therapeutic effect of Silymarin in the prevention of hepatic lesion induced by antituberculot-ic. Method 486 patients which received anti - TB treaetment were randomly divided into the observation group(238 cases) and the control group(248 cases). The two groups all received anti -TB treaetment of 2RHZE/4RH, meanwhile the observation group plus Silymarin and the control plus inosine. Result 21 cases with hepatic lesion in the observation group(21/238, 8. 8% ) , 64 cases with hepatic lesion in the control group (64/248, 18%), and there was significant difference compared with two groups ( P < 0. 05 ). Conclusion Silymarin can prevent from hepatic lesion induced by antituberculotic, which is worthy of being recommended in clinical practice.

  11. Bragg Gratings Induced in Birefringent Optical Fiber with an Elliptical Stress Cladding

    Directory of Open Access Journals (Sweden)

    I. K. Meshkovskiy

    2013-01-01

    Full Text Available The paper presents the results of writing of type I and high-performance type II fiber Bragg gratings in birefringent optical fiber with an elliptical stress cladding by a single 20 ns pulse of KrF excimer laser (248 nm. The gratings’ efficiency produced by a single pulse was up to 100%. Experimental results on visualization of these gratings are presented.

  12. Domain Modeling: NP_060052.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_060052.3 chr1 Structure of Human Ubiquitin-Conjugating Enzyme (UBCi) Involved in... Embryo Attachment and Implantation p1zuob_ chr1/NP_060052.3/NP_060052.3_apo_248-387.pdb blast 250V,253T,254D,257M,258K,260L,261R,264Y,278L,281D,282S,283L,284Y,322K 351C 0 ...

  13. On the Far Bank: The Effects of Gap Crossing on Operational Reach

    Science.gov (United States)

    2015-05-25

    Operational Arts Studies Fellowship, Advanced Military Studies Program. 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12...across a river. 118 Whiting, 125; Allen, 248. 35 Case Study: Operation Badr Context In October of 1973, Egypt launched a massive assault across...the global stage, the victory caught the attention of the world’s superpowers, with the Soviet Union and America effectively taking sides with Egypt

  14. Role of the Hepatitis C Virus Core+1 Open Reading Frame and Core cis-Acting RNA Elements in Viral RNA Translation and Replication▿ †

    Science.gov (United States)

    Vassilaki, Niki; Friebe, Peter; Meuleman, Philipe; Kallis, Stephanie; Kaul, Artur; Paranhos-Baccalà, Glaucia; Leroux-Roels, Geert; Mavromara, Penelope; Bartenschlager, Ralf

    2008-01-01

    Four conserved RNA stem-loop structures designated SL47, SL87, SL248, and SL443 have been predicted in the hepatitis C virus (HCV) core encoding region. Moreover, alternative translation products have been detected from a reading frame overlapping the core gene (core+1/ARFP/F). To study the importance of the core+1 frame and core-RNA structures for HCV replication in cell culture and in vivo, a panel of core gene silent mutations predicted to abolish core+1 translation and affecting core-RNA stem-loops were introduced into infectious-HCV genomes of the isolate JFH1. A mutation disrupting translation of all known forms of core+1 and affecting SL248 did not alter virus production in Huh7 cells and in mice xenografted with human liver tissue. However, a combination of mutations affecting core+1 at multiple codons and at the same time, SL47, SL87, and SL248, delayed RNA replication kinetics and substantially reduced virus titers. The in vivo infectivity of this mutant was impaired, and in virus genomes recovered from inoculated mice, SL87 was restored by reversion and pseudoreversion. Mutations disrupting the integrity of this stem-loop, as well as that of SL47, were detrimental for virus viability, whereas mutations disrupting SL248 and SL443 had no effect. This phenotype was not due to impaired RNA stability but to reduced RNA translation. Thus, SL47 and SL87 are important RNA elements contributing to HCV genome translation and robust replication in cell culture and in vivo. PMID:18799568

  15. Survey of Software Metrics in the Department of Defense and Industry

    Science.gov (United States)

    1994-04-01

    NAWC-92-SR- 1. [Sackman 1967] Sackman, Harold . 1967. Computers, System Science, and Evolving Society. New York: Wiley. [SAF/AQ 1994] Department of...Reconciliation Between Process and Product Views. Journal of Systems and Software 12: 243-248. 0 Lasky , Jeffrey and Kevin Donaghy. May 1993. Conflict...of Systems and Software 12: 233-241. Sackman, Harold . 1967. Computers, System Science, and Evolving Society. New York: Wiley. SAIC Metrics Working

  16. Aluminum-based water treatment residual use in a constructed wetland for capturing urban runoff phosphorus: Column study

    Science.gov (United States)

    Aluminum-based water treatment residuals (Al-WTR) have a strong affinity to sorb phosphorus. In a proof-of-concept greenhouse column study, Al-WTR was surface-applied at 0, 62, 124, and 248 Mg/ha to 15 cm of soil on top of 46 cm of sand; Al-WTR rates were estimated to capture 0, 10, 20, and 40 year...

  17. TE/TM (Transverse Magnetic/Transverse Electric) Height Profile Measurements of Transpolar VLF (Very Low Frequency) Signals,

    Science.gov (United States)

    1987-10-01

    GQD U.K. 096 3740 [NA]’ 19.6 GBZ Criggion, U.K. 096 3740 10, 20.25 IDO Rome, Italy 086 5260 [NA] 21.4 NSS Annapolis, Md. 190 4180 266 23.4 NPM Haiku ...night no yes yes 23.4 Haiku , Hawaii night no yes yes 24.8 Jim Creek, Wash. night no yes yes 26.1 TACAMO night no no yes 50 TE 40 TM -- 30- M 20- 10

  18. Prevalent Hallucinations during Medical Internships: Phantom Vibration and Ringing Syndromes

    OpenAIRE

    Yu-Hsuan Lin; Sheng-Hsuan Lin; Peng Li; Wei-Lieh Huang; Ching-Yen Chen

    2013-01-01

    BACKGROUND: Phantom vibration syndrome is a type of hallucination reported among mobile phone users in the general population. Another similar perception, phantom ringing syndrome, has not been previously described in the medical literature. METHODS: A prospective longitudinal study of 74 medical interns (46 males, 28 females; mean age, 24.8±1.2 years) was conducted using repeated investigations of the prevalence and associated factors of phantom vibration and ringing. The accompanying sympto...

  19. Fluorinated Silsesquioxanes: Structure, Solubility, and Wetting (Briefing charts)

    Science.gov (United States)

    2015-08-01

    values based on Hansen Solubiliy Parameters (for “liquid” surfaces) γlv (dyn / cm) γdlv (dyn / cm) Fluorodecyl T8 (est. HSP) 34.6 24.8 Fluorohexyl T8 (est...Charts 3. DATES COVERED (From - To) July 2015-July 2015 4. TITLE AND SUBTITLE FLUORINATED SILSESQUIOXANES: STRUCTURE, SOLUBILITY , AND WETTING...FLUORINATED SILSESQUIOXANES: STRUCTURE, SOLUBILITY , AND WETTING Joseph Mabry, Andrew Guenthner, Scott Iacono, Raymond Campos, Sean Ramirez, Brian Moore

  20. Aquatic Plant Control Research Program. Moneoecious hydrilla in the Potomac River.

    Science.gov (United States)

    1985-08-01

    omy 24:29-96. Pulich, W. M., Jr. 1982. Edaphic factors related to shoalgrass ( Halodule Wrightii Aschers.) production. Botanica Marina 25:467-475...dwelling organisms. The best available data concerning the benthic macroinvertebrate fauna of the freshwater tidal portion of the Potomac were...oxygenators in rivers. Water Research 2:243-248. Egglishaw, H. J. 1964. The distributional relationship between the bottom fauna and plant detritus in